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Sample records for facial seborrheic dermatitis

  1. Seborrheic dermatitis

    Science.gov (United States)

    Dandruff; Seborrheic eczema; Cradle cap ... The exact cause of seborrheic dermatitis is unknown. Doctors think it may be due to a combination hormone levels, weakened immune system, lack of certain nutrients, or ...

  2. Comparison of different regimens of pimecrolimus 1% cream in the treatment of facial seborrheic dermatitis.

    Science.gov (United States)

    Zhao, Juemin; Sun, Wenjia; Zhang, Chengfeng; Wu, Jiaqiang; Le, Yan; Huang, Chunyun; Liu, Ye; Xiang, Leihong

    2017-06-07

    Pimecrolimus 1% cream has already been proved to be an effective and safe alternative to treat seborrheic dermatitis. However, the treatment periods were inconstant in previous studies. To evaluate the comparative efficacy of pimecrolimus 1% cream with different regimens for the treatment of facial seborrheic dermatitis. Thirty patients with facial seborrheic dermatitis were enrolled and randomly distributed to three groups. Patients of Group 1 were treated with topical pimecrolimus cream 1% twice daily for 2 weeks and then a moisturizer cream twice daily for 2 weeks. Patients of Group 2 were treated with pimecrolimus cream 1% twice daily for 2 weeks and then once daily for another 2 weeks. Patients of Group 3 had a consecutive course of pimecrolimus cream 1% twice daily for 4 weeks. Objective symptoms, subjective symptoms, and dermatology life quality index (DLQI) were measured at weeks 0, 2, 4, and 6. At week 4, the clinical severity scores of all three regimens significantly decreased (Peffect was maintained until the end of the study in Group 3. Life quality of all three groups was significantly improved at week 4 (Pcream could be applied twice a day for 4 weeks to treat seborrheic dermatitis. © 2017 Wiley Periodicals, Inc.

  3. Seborrheic dermatitis and homeopathy

    Directory of Open Access Journals (Sweden)

    Lawrence Chukwudi Nwabudike

    2011-10-01

    Full Text Available Introduction: Seborrheic dermatitis is a common, usually mild skin condition affecting both sexes. Infants as well as adults may be afflicted. It may cause discomfort when not properly treated. Seborrheic dermatitis is in the spectrum of diseases found frequently in HIV infected patients and in people with AIDS. Various treatment modalities exist, all aimed at control and not cure of the disease. Homeopathy is a system of treatment that is cheap, apparently free of side-effects, does not interact with regular medications and is widely applicable in many fields of medicine, including dermatology. Any new, but efficacious, treatment modality is always welcome in dermatology. Materials and methods: Two patients with seborrheic dermatitis of varying severity and duration were treated with homeopathy and the results documented. Results: The patients recovered fully and are still in remission years later. Conclusions: Homeopathy may be of use in the treatment of acute and chronic seborrheic dermatitis. Since it is cheap, free of side-effects and does not interfere with regular medication, it may become an attractive option in the treatment of this disorder, especially in patients with multiple pathologies.

  4. Facial seborrheic dermatitis: a report on current status and therapeutic horizons.

    Science.gov (United States)

    Bikowski, Joseph

    2009-02-01

    Seborrheic dermatitis, characterized by erythema and/or flaking or scaling in areas of high sebaceous activity, affects up to 5% of the US population and often appears in conjunction with other common skin disorders, such as rosacea and acne. Despite ongoing research, its etiology is puzzling. Increased sebaceous and hormonal (androgenic) activity is thought to play a part. Recent evidence suggests an important role for individual susceptibility to irritant metabolites of the skin commensal Malassezia, most probably M globosa. Current approaches thus include agents with antifungal as well as antikeratinizing, and anti-inflammatory activity. Azelaic acid, which has all 3 properties, may be a useful addition to first-line management, which now comprises of topical steroids, the immunosuppressant agents tacrolimus and pimecrolimus, azoles and other antifungals, and keratolytic agents. A recent exploratory study supports the efficacy and safety of azelaic acid 15% gel in seborrheic dermatitis. Azelaic acid may be especially valuable in this application because of its efficacy in treating concomitant rosacea and acne.

  5. Hydrocortisone 1% cream and sertaconazole 2% cream to treat facial seborrheic dermatitis: A double-blind, randomized clinical trial.

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    Balighi, K; Ghodsi, S Z; Daneshpazhooh, M; Ghale-Baghi, S; Nasimi, M; Azizpour, A

    2017-06-01

    Seborrheic dermatitis (SD) is a chronic dermatitis with periods of remission and relapse that requires long-term treatment. We compared the efficacy and safety of treatment with sertaconazole with standard corticosteroid medications in adults with facial SD. In this double-blind, randomized controlled trial, 60 patients with a diagnosis of SD were enrolled. Patients were instructed to apply either sertaconazole 2% cream (30 patients) or hydrocortisone 1% cream (30 patients) twice daily to the affected area of the face. The severity of facial SD was assessed at 0, 2, and 4 weeks of treatment. Secondary efficacy measures included patient assessment of seborrhea, adverse events, and improvement percentage (IP). SD lesions cleared significantly (p .05). Both treatments resulted in significant improvement of SD lesions and the rate of adverse events was similar in both groups. The IP was higher for treatment with hydrocortisone in Week 2 and similar in both groups at the end of the study. Limitations include the small number of patients who were recruited for this study and the lack of evaluation of time to relapse. Treatment with topical sertaconazole may be regarded as a substitute for topical corticosteroid medications due to the fewer adverse events and similar efficacy.

  6. Ciclopirox shampoo for treating seborrheic dermatitis.

    Science.gov (United States)

    Gupta, A K; Bluhm, R

    2004-01-01

    Seborrheic dermatitis is a common inflammatory skin disease, affecting between 1% and 3% of immunocompetent adults. While its cause is unknown, a number of predisposing factors have been reported, including the implications of Malassezia yeasts. Various treatment options are available, such as ciclopirox shampoo, which combines anti-Malassezia activity with an anti-inflammatory action. This agent has been shown to be an effective and safe treatment for seborrheic dermatitis of the scalp.

  7. Management of seborrheic dermatitis and pityriasis versicolor.

    Science.gov (United States)

    Faergemann, J

    2000-01-01

    Pityriasis (tinea) versicolor and seborrheic dermatitis are two very common skin diseases. Pityriasis versicolor is a chronic superficial fungal disease usually located on the upper trunk, neck, or upper arms. In pityriasis versicolor, the lipophilic yeast Malassezia (also know as Pityrosporum ovale or P. orbiculare) changes from the blastospore form to the mycelial form under the influence of predisposing factors. The most important exogenous factors are high temperatures and a high relative humidity which probably explain why pityriasis versicolor is more common in the tropics. The most important endogenous factors are greasy skin, hyperhidrosis, hereditary factors, corticosteroid treatment and immunodeficiency. There are many ways of treating pityriasis versicolor topically. Options include propylene glycol, ketoconazole shampoo, zinc pyrithione shampoo, ciclopiroxamine, selenium sulfide, and topical antifungals. In difficult cases, short term treatment with fluconazole or itraconazole is effective and well tolerated. To avoid recurrence a prophylactic treatment regimen is mandatory. Seborrheic dermatitis is characterized by red scaly lesions predominantly located on the scalp, face and upper trunk. There are now many studies indicating that Malassezia plays an important role in this condition. Even a normal number of Malassezia will start an inflammatory reaction. Mild corticosteroids are effective in the treatment of seborrheic dermatitis. However, the disease recurs quickly, often within just a few days. Antifungal therapy is effective in the treatment of seborrheic dermatitis and, because it reduces the number of Malassezia, the time to recurrence is increased compared with treatment with corticosteroids. Antifungal therapy should be the primary treatment of this disease.

  8. Ciclopirox 1% shampoo for the treatment of seborrheic dermatitis.

    Science.gov (United States)

    Gupta, Aditya K; Nicol, Karyn A

    2006-01-01

    Seborrheic dermatitis is a chronic superficial fungal infection of the skin, particularly affecting sites rich in sebaceous glands. Although the precise etiology of seborrheic dermatitis is uncertain, yeasts of the genus Malassezia are known to play a causative role. Ciclopirox is a broad-spectrum, hydroxypyridone-derived, synthetic antifungal agent, which also has anti-inflammatory properties. Ciclopirox is effective both in vitro and in vivo against Malassezia yeasts, making it a valuable option for the treatment of seborrheic dermatitis. Varying frequencies and concentrations of ciclopirox shampoo have been shown to be effective and safe in the treatment of seborrheic dermatitis of the scalp.

  9. Scalp Psoriasis vs. Seborrheic Dermatitis: What's the Difference?

    Science.gov (United States)

    ... does a doctor tell the difference between scalp psoriasis and seborrheic dermatitis of the scalp? Answers from ... such as pitting. Compare signs and symptoms Scalp psoriasis Red skin covered with flakes and silvery scales ...

  10. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study

    Science.gov (United States)

    Youn, Hae Jeong; Kim, Soo Young; Park, Minji; Jung, Won Hee; Choe, Yong Beom; Ahn, Kyu Joong

    2016-01-01

    Background Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. Objective We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms. Methods We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks. The casual sebum level (measured with Sebumeter®; Courage & Khazaka Electronic GmbH, Germany) and the extent of erythema (measured with Mexameter®; Courage & Khazaka Electronic GmbH) on the face were measured at baseline and after 4 weeks. The minimal inhibitory concentration (MIC) was determined to demonstrate the antifungal activity of the C/P cream. Results The casual sebum level and erythema were measured at week 4, and the median values demonstrated a quantitative improvement on the C/P cream-treated right side of the face compared to the emollient cream-treated left side. For the C/P cream, the MICs were 0.625, 5, 0.625, and 2.5 mg/ml for Malassezia restricta, M. globosa, M. sympodialis, and M. slooffiae, respectively. Conclusion Based on the reduced casual sebum level and extent of erythema, the antifungal activity of C/P cream against Malassezia species seems useful for the treatment of mild to moderate SD. PMID:27904273

  11. Efficacy and Safety of Cream Containing Climbazole/Piroctone Olamine for Facial Seborrheic Dermatitis: A Single-Center, Open-Label Split-Face Clinical Study.

    Science.gov (United States)

    Youn, Hae Jeong; Kim, Soo Young; Park, Minji; Jung, Won Hee; Lee, Yang Won; Choe, Yong Beom; Ahn, Kyu Joong

    2016-12-01

    Seborrheic dermatitis (SD) is a multifactorial disease; Malassezia species play an important role in its pathogenesis. We aimed to determine whether a cream containing climbazole/piroctone olamine (C/P cream), antifungal agents with expected efficacy against Malassezia species, could improve SD symptoms. We instructed 24 patients with mild-to-moderate SD to apply the C/P cream and emollient cream on the right and left sides of the face, respectively, every morning and evening for 4 weeks. The casual sebum level (measured with Sebumeter®; Courage & Khazaka Electronic GmbH, Germany) and the extent of erythema (measured with Mexameter®; Courage & Khazaka Electronic GmbH) on the face were measured at baseline and after 4 weeks. The minimal inhibitory concentration (MIC) was determined to demonstrate the antifungal activity of the C/P cream. The casual sebum level and erythema were measured at week 4, and the median values demonstrated a quantitative improvement on the C/P cream-treated right side of the face compared to the emollient cream-treated left side. For the C/P cream, the MICs were 0.625, 5, 0.625, and 2.5 mg/ml for Malassezia restricta, M. globosa, M. sympodialis, and M. slooffiae, respectively. Based on the reduced casual sebum level and extent of erythema, the antifungal activity of C/P cream against Malassezia species seems useful for the treatment of mild to moderate SD.

  12. Investigations of seborrheic dermatitis. Part I. The role of selected cytokines in the pathogenesis of seborrheic dermatitis 

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    Ewa Trznadel-Grodzka

    2012-11-01

    Full Text Available Introduction:The etiology of seborrheic dermatitis is not fully understood. It has been observed that a number of anascogenic yeasts of Malassezia spp. is related to the intensity of the symptoms. The aim of the study is to measure the concentration of selected inflammatory factors IL-2, IL-4, IFN-γ and TNF-α in the serum by an immunoenzymatic method, as well as to confirm the relationship between the studied factors and the clinical condition of the patients (sex, the intensity of skin lesions according to the Scaparro scale and, finally, to compare the results with the control group.Material/Methods:The total number of subjects who participated in the study was 66. The control group (C consisted of 30 volunteers (23 females and 7 males, with no clinical disorders, aged 24–65 (37.41±6.08 years. Thirty-six patients with seborrheic dermatitis (16 females and 20 males, aged 19–76 (38.61±13.77, made up the study group. The determination of IL-2, IL-4, IFN-γ and TNF-α was performed by ELISA using a Human High Sensitivity kit (Diaclone, France. Clinically, the intensity of the disease process was evaluated on the Scaparro et al. scale, as modified by Kaszuba.Results:We observed statistically significantly higher levels of IL-2 and IFN-γ in patients with seborrheic dermatitis compared to the control group.Conclusions:We conclude that seborrheic dermatitis is a dermatosis characterized by a cell type immune response with an important role of IFN-γ and IL-2. 

  13. 21 CFR 358.710 - Active ingredients for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Science.gov (United States)

    2010-04-01

    ..., seborrheic dermatitis, or psoriasis. 358.710 Section 358.710 Food and Drugs FOOD AND DRUG ADMINISTRATION... Psoriasis § 358.710 Active ingredients for the control of dandruff, seborrheic dermatitis, or psoriasis. The... psoriasis. (1) Coal tar, 0.5 to 5 percent. When a coal tar solution, derivative, or fraction is used as...

  14. Seborrheic dermatitis due to Malassezia species in Ahvaz, Iran.

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    Ali Zarei-Mahmoudabadi

    2013-09-01

    Full Text Available Seborrheic dermatitis (SD is a frequent disorder of the skin that is distinguished by the development of erythematous patches and yellow-gray scales. It is a multifactor disease that requires predisposing factors for its progress. Presence of these factors leads to reproduction of opportunistic yeast Malassezia spp. The aim of the present study was to isolate and identify distribution of Malassezia species on the scalp of SD patients in Ahvaz using modified Dixons agar.A total of 110 patients diagnosed with SD were sampled. The sampling was carried out by brushing the hair and collecting the dandruff in paper pockets. For identification of Malassezia species, the scalp scales were cultured in Dixons agar. A combination of different characteristics including yeast cell morphology, ability to grow on Sabouraud dextrose agar, catalase test and ability to utilize individual Tweens (20, 40, 60 & 80 were used for identification of species.Twenty-seven of 110 (24.5% SD patients had positive cultures for Malassezia species of which 17 (63% were male and 10 (37% were female. The most commonly identified Malassezia species was M. globosa (40.7% followed by M. pachydermatis (22.2%, M. furfur (11.1% and M. restricta(7.4% and Malassezia species (18.5%.Malassezia globosa was considered to be the most important orgaism involved in cases with Seborrheic dermatitisin this study.

  15. 21 CFR 358.750 - Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis.

    Science.gov (United States)

    2010-04-01

    ... dandruff, seborrheic dermatitis, or psoriasis. 358.750 Section 358.750 Food and Drugs FOOD AND DRUG... Dermatitis, and Psoriasis § 358.750 Labeling of drug products for the control of dandruff, seborrheic dermatitis, or psoriasis. (a) Statement of identity. The labeling of the product contains the...

  16. 脂溢性皮炎治疗进展%Research progress in the treatment of seborrheic dermatitis

    Institute of Scientific and Technical Information of China (English)

    于越; 王国江

    2016-01-01

    脂溢性皮炎的药物治疗主要集中在抗真菌药及钙调神经磷酸酶抑制剂,外用糖皮质激素、烟酰胺及透明质酸钠等也有报告。因长期外用糖皮质激素有诱发激素依赖性皮炎的风险,已经逐渐少用,烟酰胺及透明质酸钠治疗脂溢性皮炎还有待更多文献支持。脂溢性皮炎的物理治疗主要集中在强脉冲光及光动力治疗,这些治疗可以减少皮脂腺的分泌、减轻皮肤红斑,值得深入探索。窄谱中波紫外线治疗面部脂溢性皮炎因有色素再生风险受到一定限制。射频治疗脂溢性皮炎的疗效还处于试用阶段。%The treatment of seborrheic dermatitis by medicine, mainly focused on antifungal agents and calcineurin inhibitors. The applications of topical corticosteroids, nicotinamide and sodium hyaluronate have also been reported. Since long-term topical treatment with glucocorticoid steroid may induce hormone dependent dermatitis, the method is less adopted now. The application of nicotinamide and hyaluronic acid sodium in the treatment of seborrheic dermatitis remains to be studied. The physical treatment of seborrheic dermatitis mainly concentrates in the intense pulse light and photodynamic therapy, which can reduce sebaceous gland secretion of oils and fats, relieve the skin erythema, and worthy exploring. Narrow spectrum ultraviolet treatment of facial seborrheic dermatitis may induce homogeneous repigmentation, which limits its application. Treating seborrheic dermatitis with radiofrequency is still in the trial stage.

  17. 脂溢性皮炎治疗心得%Experience of treating seborrheic dermatitis

    Institute of Scientific and Technical Information of China (English)

    张先雷; 孟胜利

    2016-01-01

    The incidence of seborrheic dermatitis was high and the clinical effect of western medicine was not good.In this paper, the author summarized the experience of traditional Chinese medicine in the treatment of seborrheic dermatitis and pointed out that traditional Chinese medicine combined with good habits could treat seborrheic dermatitis effectively.%目的:脂溢性皮炎发病率较高,西医治疗效果不佳。本文总结中医治疗脂溢性皮炎的经验,指出中医治疗联合良好的生活习惯可有效治疗脂溢性皮炎。

  18. Dermoscopic findings in scalp psoriasis and seborrheic dermatitis; Two new signs; Signet ring vessel and hidden hair

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    Melike Kibar

    2015-01-01

    Full Text Available Background: Psoriasis and seborrheic dermatitis are both chronic erythemato-squamous dermatoses that can involve the scalp. It may be difficult to differentiate these two diseases when there is isolated scalp involvement. Recently, trichoscopy is commonly used to differentiate noncicatricial alopecias including psoriasis and seborrheic dermatitis that can lead to telogen effluvium (TE. Objectives: The objective of this study is to evaluate the trichoscopic figures that may help to differentiate scalp psoriasis and seborrheic dermatitis. Materials and Methods: Thirty one with scalp psoriasis and 112 patients with seborrheic dermatitis were enrolled. Trichoscopic examinations were performed using a videodermatoscope (MoleMax 3 ® . Trichoscopic findings of scalp psoriasis and seborrheic dermatitis were compared with each other, with 100 healthy individuals and with other noncicatricial alopecias including female androgenetic alopecia (FAGA (n: 138, male androgenetic alopecia (n: 63, FAGA of male pattern (FAGA.M (n: 5, alopecia areata (39, TE (n: 22 and trichotillomania (n: 4. Results: Atypical red vessels, red dots and globules (RDG, signet ring vessels (SRV, structureless red areas and hidden hairs (HH were statistically more common in psoriasis while twisted red loops and comma vessels (CV in seborrheic dermatitis. RDG were considered as the characteristic videodermatoscopic figure for psoriasis and arborizing red lines and CV for seborrheic dermatitis. In comparison with previous reports, our study yielded two new trichoscopic structures supporting the diagnosis of psoriasis; HH and SRV. Besides, according to our study, CV were described for the first time in seborrheic dermatitis and considered to be specific for seborrheic dermatitis. Conclusion: This study confirmed that trichoscopy might be useful in differentiating scalp psoriasis and seborrheic dermatitis from each other and from other noncicatricial alopecia with three trichoscopic

  19. Fluconazole and its place in the treatment of seborrheic dermatitis--new therapeutic possibilities.

    Science.gov (United States)

    Zisova, Lilija G

    2006-01-01

    Seborrheic dermatitis is a subacute or chronic disease of the skin, affecting the seborrhea afflicted areas and presenting with erythema and desquamation. The inflammatory reaction towards the fungi Malassezia spp. is considered to have a basic etiologic connection with this disease. Taking into consideration the pathogenesis, treatment of the dermatitis should be directed towards eradication of Malassezia spp., reduction of the skin lipids, and suppression of the inflammatory response. A wide variety of agents presented in different forms--ointments, shampoos and drugs--can offer quick, safe and effective treatment alternatives. The purpose of the present study was to monitor the therapeutic effects of the anti-fungal drug fluconazole in patients with seborrheic dermatitis. We compared two study groups of patients: Group I--27 patients with seborrheic dermatitis stage I, II and III, treated with fluconazole, 50 mg/day for two weeks. As topical therapy we applied clobetasol propionate 0.05% ointment. After the completion of the therapeutic course, 85% of the patients in this group were clinically cured and their symptoms faded away. Fifteen percent of the subjects in this group--mainly stage III seborrheic dermatitis patients, showed partial but significant clinical improvement. The specific fungal test for Malassezia spp. on Dixon agar was negative in 93% of the cases in this group. Group II--eleven patients with similar clinical indexes were treated with fluconazole 50 mg/day only, for the same time period. The therapeutic results in this group were also satisfactory--31.5% of the patients were cured and 68.5% showed clinical improvement. In 74% of the patients the specific test for Malassezia spp. was negative after treatment. Fluconazole treatment in patients with seborrheic dermatitis proves to be successful, effective and safe.

  20. A Comprehensive Pathophysiology of Dandruff and Seborrheic Dermatitis - Towards a More Precise Definition of Scalp Health

    DEFF Research Database (Denmark)

    Schwartz, James R; Messenger, Andrew G; Tosti, Antonella

    2012-01-01

    Despite an increasing knowledge of dandruff and seborrheic dermatitis (D/SD), the pathophysiological understanding is still incomplete but suggests a role of Malassezia yeasts in triggering inflammatory and hyper-proliferative epidermal responses. The objective of this report is to review published...

  1. Clinical Characteristics and Quality of Life of Seborrheic Dermatitis Patients in a Tropical Country.

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    Araya, Manapajon; Kulthanan, Kanokvalai; Jiamton, Sukhum

    2015-01-01

    Seborrheic dermatitis is a common chronic inflammatory skin condition that can have a negative impact on a patient's quality of life. Few studies have been conducted to assess the clinical characteristics of the disease and quality of life of the patients, especially in tropical countries. The aim of this study was to demonstrate the clinical characteristics and quality of life of patients with seborrheic dermatitis in Thailand. A cross-sectional study was performed at a university-based hospital and tertiary referral center in Bangkok, Thailand. The validated Thai version of the dermatology life quality index (DLQI) was used to evaluate patients' quality of life. A total of 166 participants were included. One hundred and forty-seven patients (88.6%) experienced multiple episodes of the eruption. The mean of outbreaks was 7.8 times per years, ranging from once every 4 years to weekly eruption. The most common factor reported to aggravate seborrheic dermatitis was seasonality (34.9%), especially hot climate. The mean (SD) of the total DLQI score was 8.1 (6.0) with a range of 0 to 27. There was no statistically significant difference between the two DLQI categories regarding duration of disease, extent of involvement, symptoms or course of the disease. Although mild and asymptomatic, seborrheic dermatitis can have a great impact on the quality of life. Youth, female gender, and scalp lesions were significantly associated with higher DLQI scores.

  2. Study on the Relationship between Seborrheic Dermatitis and Psoriasis%脂溢性皮炎和银屑病关系的研究

    Institute of Scientific and Technical Information of China (English)

    王菲丽

    2015-01-01

    By understanding seborrheic dermatitis and psoriasis patients with head and facial features and skin rash in patients with a history of psoriasis,sebor heic dermatitis,incidence,histopathological changes,etc.to explore the relationship between the two.%通过了解脂溢性皮炎和银屑病患者头面部皮疹的特征以及银屑病患者脂溢性皮炎的病史,发病情况,组织病理学改变等情况,探讨二者之间的关系。

  3. Clinical efficacy of a new ciclopiroxolamine/zinc pyrithione shampoo in scalp seborrheic dermatitis treatment.

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    Lorette, Gérard; Ermosilla, Valérie

    2006-01-01

    Ciclopiroxolamine (CPO) and Zinc Pirythione (ZP) antifungals are efficient at treating scalp seborrheic dermatitis. This multicentre, single-blind, clinical study was conducted to evaluate the efficacy of a shampoo containing the 1.5% CPO/1% ZP association compared to the vehicle shampoo and to 2% ketoconazole foaming gel in the treatment of seborrheic dermatitis. In 189 patients randomised to apply 1 of the 3 products twice a week for 28 days, the global lesional score, erythema, pruritus, global efficacy, quality of life (SF12 and DLQI questionnaires) and tolerance were measured at 0, 7, 14 and 28 days. The 3 products reduced lesional score, erythema and pruritus from day 7 (p shampoo was more efficient in reducing pruritus than ketoconazole gel and vehicle (p = 0.032 and p shampoo improved all DLQI questionnaire dimensions. The CPO/ZP shampoo was as rapid and efficient as ketoconazole gel in SD treatment.

  4. Humoral immunity to Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrheic dermatitis and controls.

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    Ashbee, H R; Fruin, A; Holland, K T; Cunliffe, W J; Ingham, E

    1994-10-01

    This study examined the humoral immune responses to Malassezia furfur serovars A, B and C of 10 patients with pityriasis versicolor, 10 patients with seborrheic dermatitis and 20 age- and sex-matched controls. A transferable solid-phase ELISA was used to determine titres of total Igs, IgM, IgA and IgG specific to M. furfur serovars A, B and C. The results demonstrated that patients with seborrheic dermatitis had a significantly higher titre of total Igs to serovar A than patients with pityriasis versicolor; and that patients with seborrheic dermatitis had a significantly higher titre of IgA to serovar C than patients with pityriasis versicolor. The titres of total Igs for controls and patients with seborrheic dermatitis were significantly lower to serovar B than to serovar C. A modified TSP ELISA was used to determine the titres of the IgG subclasses. Titres of IgG1,3,4 to serovar B were significantly higher in seborrheic dermatitis patients than pityriasis versicolor patients and titres of IgG3 to serovar A were significantly higher in seborrheic dermatitis patients than pityriasis versicolor patients. However, despite the differences between the patient groups, none of these results was significantly different to those of controls. Thus, this study did not demonstrate any differences in humoral immunity of patients suffering from Malassezia-associated dermatoses when compared to normal controls. These results may suggest that the humoral immune response to M. furfur is not related to the pathogenesis of Malassezia-associated dermatoses, but simply to the carriage of M. furfur on the skin.

  5. Identification of Malassezia Species Isolated from Patients with Seborrheic Dermatitis Using PCR-RFLP Method in Arak, Iran

    Directory of Open Access Journals (Sweden)

    Mohajerani, HR. (PhD

    2015-01-01

    Full Text Available Background and Objective: Malassezia that is a part of normal flora is lipophilic yeast involved in a variety of skin diseases such as seborrheic dermatitis, pityriasis versicolor, atopic dermatitis and psoriasis. Seborrheic dermatitis affects most often the sebaceous-gland-rich areas of skin such as face, scalp, and parts of the upper trunk. Dandruff is a mild variant of seborrheic dermatitis characterized by scaling. In this study, Malassezia species causing dandruff were identified. Material and Methods: In this descriptive study, the samples (n= 60 from participants with dandruff were examined under a microscope using 10% KOH solution and cultured in Leeming and Notman ager medium. DNA Extraction was performed from colonies by glass bead and the Malassezia genus, and species were detected by CfoI enzyme using PCR-RFLP method Results: Of 60, 40 (66.6% were positive for Malassezia yeast. The positive samples in direct examination grew in culture medium. Malassezia species isolated were Malassezia globosa (25 cases, Malassezia restricta (10 cases, Malassezia furfur (3 cases and Malassezia sympodialis (2 cases. Conclusions: In most studies, the Malassezia species were identified as the agents causing seborrheic dermatitis. In our study, Malassezia globosa was isolated as a dominant species.

  6. Environmental exogenous factors and facial dermatitis: A case control study

    Directory of Open Access Journals (Sweden)

    Wen-Hui Wang

    2017-03-01

    Conclusions: Contact factors play an important role in facial dermatitis. Aggravation by sunlight exposure, ingestion of spicy food, or alcohol are more reported in facial dermatitis compared with nonfacial dermatitis.

  7. Detection of Malassezia Species Isolated From Patients With Pityriasis Versicolor and Seborrheic Dermatitis Using Nested-PCR

    Directory of Open Access Journals (Sweden)

    Zarei Mahmoudabadi

    2014-12-01

    Full Text Available Background The species of the genus Malassezia are lipophilic and dimorphic yeasts that are regarded as part of the normal flora of the skin of humans and warm-blooded animals. These organisms are the cause of superficial mycosis in humans and other animals, and are common in pityriasis versicolor and seborrheic dermatitis. Objectives The purpose of this study was to determine the frequency of common Malassezia species in patients affected by pityriasis versicolor and seborrheic dermatitis using of the nested PCR method, in the city of Ahvaz. Patients and Methods In the present study, 85 samples from patients with pityriasis versicolor and seborrheic dermatitis were analyzed by the nested-PCR method. During the first stage, the internal transcribed spacer (ITS region from the ribosomal DNA was reproduced using primers ITS4-R and ITS1F-N. During the second stage, the product of the first step was used as DNA and using three special primer pairs, including Mf-F, 5.8SR and M.gl-F, 5.8SR and M.rt-F and M.rt-R, the inner part of the first phase was detected. Results The most common isolate was Malassezia furfur (51.3% followed by M. globosa (35.2% and M. restricta (13.5%. Amongst the 30 patients with seborrheic dermatitis, in 15 cases (65.2% M. restricta, in six cases (26.1% M. globosa and in two cases (8.7% M. furfur was detected and in seven patients no isolate was detected. Conclusions The nested-PCR is a rapid and repeatable method for identification of important Malassezia species and this method is recommended for use on more patients. In addition the most common agents of pityriasis versicolor and seborrheic dermatitis were M. furfur and M. restricta, respectively.

  8. Nursing experience of patients with seborrheic dermatitis%脂溢性皮炎患者的护理体会

    Institute of Scientific and Technical Information of China (English)

    及跃男

    2014-01-01

    目的:探讨脂溢性皮炎患者在门诊诊治过程中的护理方法和体会。方法根据脂溢性皮炎患者的特点,进行个性化护理。结果161例患者中,治愈73例,好转79例,无效9例。结论宣教、健康指导和护理是对门诊脂溢性皮炎患者提高自我保健、正确面对疾病、积极配合医生治疗的有效方法。%Objective To explore the nursing approaches and experience during the diagnosis and treatment of seborrheic dermatitis patients in outpatient. Methods Individualized nursing was implemented according to the characteristics of the patients with seborrheic dermatitis. Results The patients’ awareness of prevention and treatment of disease is enhanced by our health guidance and care. Thus, a good therapeutic effect is obtained. Conclusion Education, health guidance and care are effective approaches to improve self-care, face the disease correctly and cooperate with medical treatment actively for outpatient seborrheic dermatitis.

  9. Parasympathetic nervous system and chronic facial dermatitis.

    Science.gov (United States)

    Koehler, Irmgard Kilb

    2009-01-01

    Recognizing the focal role of the CNS and stress in the pathogenesis of chronic facial dermatitis, the author hypothesized that the main responsibility for the persistence of CFD lies in the parasympathetic portion of the CNS. The validity of this hypothesis is challenged with organ specific treatments, leading to the resolution of parasympathetic stress and CFD.

  10. Formulation and Evaluation of Hair Gel for the Treatment of Chronic Inflammatory Disorder Seborrheic Dermatitis

    Directory of Open Access Journals (Sweden)

    Sharma M

    2013-10-01

    Full Text Available Dandruff is a condition in which dead skin cells from the scalp come off in scales that are visible on the hair. The scales are dry, white or greyish and appear as small patches, especially at the top of the head. Dandruff may be a symptom of a more serious problem, such as seborrheic dermatitis. Various Antifungal agents are widely used in hair shampoos for the treatment of dandruff. These products show temporary effect for span of hours in a day on the scalp. Therefore, an attempt has been made for formulation of Ketoconazole Anti-dandruff hair gels which may give antidandruff action for number of hours. All the formulations were evaluated Active Content, Physical appearance, PH, Viscosity, Extrudability, Antifungal activity, Drug release Profile and Stability study. The formulation HG3 shows superior drug release than other formulations. In carbopol gel formulations, the drug release was decrease with increase in carbopol concentration Antimicrobial activity shows that formulation HG3 shows higher efficacy without any dermal irritancy. Moreover the optimized formulation showed no signs of irritation or inflammation.

  11. Sympathetic skin responses from the scalp evoked by electrical stimulation in seborrheic dermatitis.

    Science.gov (United States)

    Altunrende, Burcu; Yildiz, Serpil; Kandi, Basak; Yildiz, Nebil

    2013-06-01

    Although the role of autonomic nervous system in seborrheic dermatitis (SD) is still unclear, seborrhea is sometimes accepted as a sign of autonomic dysfunction in several nervous system diseases. Therefore, we aimed to investigate the sympathetic nervous system (SNS) activity in SD by recording sympathetic skin responses (SSR) from the scalp (S-SSR). Thirty-one control subjects and 22 SD patients were studied by evoking right and left S-SSR with electrical stimulation of the right median nerve at the wrist. Mean latencies and maximum amplitudes were calculated for both sides in each group. In seven out of 31 control subjects and in 13 out of 22 patients, the S-SSR could not be elicited on either side. There were four subjects with unilateral response in the patient group. There were significantly more non-responders among the patients with SD (P < 0.000). This study suggests that in SD, the autonomic nervous system may be involved. The S-SSR is a new site for recording SSR. The responses are relatively symmetrical and can be evoked easily by electrical stimulation, and may be used to evaluate the SNS function in SD patients and also in healthy subjects.

  12. Investigation of hair shaft in seborrheic dermatitis using atomic force microscopy.

    Science.gov (United States)

    Kim, Kyung Sook; Shin, Min Kyung; Ahn, Jae-Jun; Haw, Choong-Rim; Park, Hun-Kuk

    2011-08-01

    We have investigated the changes of seborrheic dermatitis (SD) on the hair shaft in the morphological and physical properties using atomic force microscopy (AFM). Hair samples were obtained from the lesional and perilesional regions in 15 patients with SD. Fifteen healthy adults were included as the control group. From the topography of hair obtained by AFM, the height of the scale, step height, roughness, diameter, and pit were determined. The scale thickness of the SD-affected hair was sevenfold more than in the control hair showing statistically significance. The lesional hair showed greater roughness parameters of Sa, Sq, and Sz than the perilesional and the control hair, but this difference was not significant. The cuticle of the lesional hair was significantly damaged while perilesional hair showed a very distinct cuticle structure with smooth edges and a regular interval between the cuticles. The diameter of the lesional hair was significantly lesser by 10-35% than that of the perilesional hair. The pit was rarely observed in the SD-affected hair collected from both the lesional and perilesional regions. The changes in the hair shaft affected SD was measured using AFM non-invasively. AFM could be a useful tool in monitoring the treatment response and the severity of SD. © 2011 John Wiley & Sons A/S.

  13. Irritant contact facial dermatitis due to nebulizer therapy.

    OpenAIRE

    Eedy, D. J.; Barton, K; Stanford, C. F.

    1988-01-01

    A case is reported of a patient with long-standing, severe airflow obstruction requiring long-term nebulizer therapy developing a facial dermatitis in the area bounded by the nebulizer mask. The facial dermatitis seems to be the result of the combined irritancy of the nebulizer solutions and moisture, and prophylactic measures are suggested for patients requiring long-term nebulizer therapy.

  14. Irritant contact facial dermatitis due to nebulizer therapy.

    Science.gov (United States)

    Eedy, D. J.; Barton, K.; Stanford, C. F.

    1988-01-01

    A case is reported of a patient with long-standing, severe airflow obstruction requiring long-term nebulizer therapy developing a facial dermatitis in the area bounded by the nebulizer mask. The facial dermatitis seems to be the result of the combined irritancy of the nebulizer solutions and moisture, and prophylactic measures are suggested for patients requiring long-term nebulizer therapy. Images Figure 1 PMID:2973007

  15. Cell-mediated immune responses to Malassezia furfur serovars A, B and C in patients with pityriasis versicolor, seborrheic dermatitis and controls.

    Science.gov (United States)

    Ashbee, H R; Ingham, E; Holland, K T; Cunliffe, W J

    1994-06-01

    It has been postulated that patients with Malassezia furfur-associated dermatoses have a deficient cell-mediated immune response to M. furfur. This study examined the cell-mediated immune responses to M. furfur serovars A, B and C of 10 patients with pityriasis versicolor and 10 age- and sex-matched controls; and 10 patients with seborrheic dermatitis and 10 age- and sex-matched controls. The responses to each serovar of M. furfur were assessed using the lymphocyte transformation assay and the leukocyte migration inhibition assay. The lymphocyte transformation responses of the patients with pityriasis versicolor to M. furfur serovars A, B and C (0/10, 6/10 and 5/10 respectively) were not significantly different from those of controls (0/10, 2/10 and 1/10). However, for patients with seborrheic dermatitis, significantly more patients' lymphocytes responded to serovars B and C (6/10 and 6/10 respectively) than those of controls (1/10 and 1/10). No patient or control responded to serovar A. In the leukocyte migration inhibition assay, the leukocytes from a greater proportion of patients with pityriasis versicolor (5/7) responded to serovar B than controls (2/10); and the leukocytes from a greater proportion of patients with seborrheic dermatitis (4/10) responded to serovar C than controls (0/9). Thus, this data did not indicate the presence of any cell-mediated immune deficiency to M. furfur in patients with pityriasis versicolor or seborrheic dermatitis, as measured by the lymphocyte transformation assay or the leukocyte migration inhibition assay. The greater responsiveness of T lymphocytes from patients may indicate that T lymphocytes might be involved in the pathogenesis of these diseases.

  16. 脂溢性皮炎与马拉色菌的关系及相关治疗研究进展%Relationship of Malassezia Furfur and Seborrheic Dermatitis and Related Researches

    Institute of Scientific and Technical Information of China (English)

    刘中华; 张慧敏

    2012-01-01

    脂溢性皮炎好发于皮脂腺丰富区,是一种慢性炎症性皮肤病.症状包括出现鳞屑,片状皮屑,瘙痒,以及湖红或红斑.普通人群中发病率为3%,虽然病因尚未完全清楚,但已知马拉色菌( Malassezia)是其主要致病因素之一.因此,文章将针对性地对脂溢性皮炎与马拉色菌的关系进行综述,并且在分析过去对马拉色菌性脂溢性皮炎的治疗方法的利弊基础上,提出新的治疗思路.%Seborrheic dermatitis often occurs on the skin where has rich sebaceous glands.It is a chronic and inflammatory skin disease and its symptoms include scales, scurf, pruritus, flushing or erythema. Morbidity of Seborrheic Dermatitis is 3% for general people. Malassezja is the main nosogenesis for Seborrheic dermatitis although the reason has not been explained completely. Trierefore, this thesis will discuss the relationship of malassezia furfur and seborrheic dermatitis. Furthermore, 晇ie will come up with a new point after thinking about trade off for treating seborrheic dermatitis resulting from malassezia furfur.

  17. Clobetasol propionate shampoo 0.05% in the treatment of seborrheic dermatitis of the scalp: results of a pilot study.

    Science.gov (United States)

    Reygagne, Pascal; Poncet, Michel; Sidou, Farzaneh; Soto, Pascale

    2007-05-01

    Seborrheic dermatitis (SD), a common dermatosis associating hyperseborrhea, erythema, itching, and dandruff, has frequent scalp involvement. Malassezia furfur infection seems to play an important role in the condition's etiopathology. Treatment of SD usually consists of corticosteroids or antifungals, such as ketoconazole. The aim of this multicenter, randomized, investigator-blinded, parallel-group pilot study was to evaluate the efficacy and safety of clobetasol propionate shampoo 0.05% after different short-contact application times compared with its vehicle and ketoconazole foaming gel 2% in the treatment of SD of the scalp. For 4 weeks, 55 subjects received one of the following treatments twice weekly: clobetasol propionate shampoo for 2.5, 5, or 10 minutes; clobetasol propionate vehicle for 10 minutes; or ketoconazole foaming gel for 5 minutes before rinsing off. Efficacy criteria included total severity score (TSS) and individual scores of signs such as itching and global improvement. Safety included reporting of burning, overall tolerance, and adverse events. Results showed that an application of clobetasol propionate for 5 and 10 minutes provided a similar mean percentage decrease of TSS, and the mean percentage decrease of TSS for all active groups was significantly superior to that of the vehicle (P shampoo is effective and safe in the treatment of SD of the scalp.

  18. Dandruff, seborrheic dermatitis, and psoriasis drug products containing coal tar and menthol for over-the-counter human use; amendment to the monograph. Final rule

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-03-15

    The Food and Drug Administration (FDA) is issuing a final rule amending the final monograph (FM) for over-the-counter (OTC) dandruff, seborrheic dermatitis, and psoriasis drug products to include the combination of 1.8 percent coal tar solution and 1.5 percent menthol in a shampoo drug product to control dandruff. FDA did not receive any comments or data in response to its previously proposed rule to include this combination. This final rule is part of FDA's ongoing review of OTC drug products.

  19. Seborrheic Dermatitis and Rosacea

    Science.gov (United States)

    ... to main content Menu For Patients All About Rosacea Faces of Rosacea Treatment Photos Rosacea FAQ Management Options What to Tell Your Physician Medical Therapy Rosacea Triggers Skin Care & Cosmetics Medical Therapy When to ...

  20. Seborrheic Dermatitis Overview

    Science.gov (United States)

    ... Boards study tools Online Learning Center Meetings and events Make a difference Career planning Media Relations Toolkit AAD apps Academy meeting Chronic urticaria—for members Chronic urticaria—for public Dermatology World Dialogues in Dermatology JAAD Mohs AUC ...

  1. Malassezia intra-specific diversity and potentially new species in the skin microbiota from Brazilian healthy subjects and seborrheic dermatitis patients.

    Directory of Open Access Journals (Sweden)

    Renan Cardoso Soares

    Full Text Available Malassezia yeasts are part of the resident cutaneous microbiota, and are also associated with skin diseases such as seborrheic dermatitis (SD. The role these fungi play in skin diseases and why they are pathogenic for only some individuals remain unclear. This study aimed to characterize Malassezia microbiota from different body sites in healthy and SD subjects from Brazil. Scalp and forehead samples from healthy, mild SD and severe SD subjects were collected. Non-scalp lesions from severe SD patients were also sampled. 5.8S rDNA/ITS2 amplicons from Malassezia sp. were analyzed by RFLP and sequencing. Results indicate that Malassezia microbiota did not group according to health condition or body area. Phylogenetic analysis revealed that three groups of sequences did not cluster together with any formally described species, suggesting that they might belong to potential new species. One of them was found in high proportions in scalp samples. A large variety of Malassezia subtypes were detected, indicating intra-specific diversity. Higher M. globosa proportions were found in non-scalp lesions from severe SD subjects compared with other areas, suggesting closer association of this species with SD lesions from areas other than scalp. Our results show the first panorama of Malassezia microbiota in Brazilian subjects using molecular techniques and provide new perspectives for further studies to elucidate the association between Malassezia microbiota and skin diseases.

  2. Possible photoactivated dermatitis with features of post-inflammatory pigmentary alteration (PIPA) and rosacea.

    Science.gov (United States)

    Orme, Charisse M; Shvartsbeyn, Marianna; Meehan, Shane A; Kornreich, Craig; Ramachandran, Sarika; Soter, Nicholas A

    2015-12-16

    Cutaneous flushing and facial erythema are common dermatologic conditions that elicit a wide differential diagnosis that includes rosacea, seborrheic dermatitis, photodermatitis, connective-tissue diseases, carcinoid syndrome, and mastocytosis. Herein we present an usual case of a mask-like rosacea-PIPA overlap that occurred in a patient with prior history of rectal carcinoid tumor and a negative systemic evaluation.

  3. Biofilm production and antifungal susceptibility of co-cultured Malassezia pachydermatis and Candida parapsilosis isolated from canine seborrheic dermatitis.

    Science.gov (United States)

    Bumroongthai, K; Chetanachan, P; Niyomtham, W; Yurayart, C; Prapasarakul, N

    2016-07-01

    The yeasts Malassezia (M.) pachydermatis and Candida (C.) parapsilosis are often co-isolated in case of canine seborrhea dermatitis (SD) and also are emerging as opportunistic pathogens of immunocompromised human beings. Increased information about how their relationship results in biofilm production and an antifungal response would be useful to inform treatment and control. This study was designed to investigate biofilm production derived from co-culture of M. pachydermatis and C. parapsilosis from dog skin and to determine their in vitro antifungal susceptibility. We demonstrated that regardless of yeast strain or origin all single and dual cultures produced biofilms within 24 hours, and the greatest amount was present after 72 hours. Biofilm production from mixed cultures was greater than for single strains (P < .05). All sessile forms of the single and dual cultures were resistant to the tested antifungals itraconazole and ketoconazole, whereas planktonic forms were susceptible. The study suggests that dual cultures produce stronger biofilms that are likely to enhance persistence in skin lesions in dogs and result in greater resistance to antifungal treatment.

  4. Seborrheic Dermatitis: Signs and Symptoms

    Science.gov (United States)

    ... K, Goldsmith LA, Katz SI, et al. editors. Fitzpatrick’s Dermatology in General Medicine, 7th ed . United States ... K, Goldsmith LA, Katz SI, et al . editors. Fitzpatrick’s Dermatology in General Medicine , 7th ed. United States ...

  5. Efficacy observation and nursing experience on treating lactating women head seborrheic dermatitis in TCM outside governance%中药外治哺乳期妇女头部脂溢性皮炎的疗效观察及护理体会

    Institute of Scientific and Technical Information of China (English)

    胥华

    2012-01-01

      Objective:To evaluate the efficacy and nursing experience of treating lactating women head seborrheic dermatitis in TCM outside governance. Methods:Treating 120 patients with lactating women head seborrheic dermatitis in TCM outside governance. Results: 120 patients were all cured. Conclusion: Treating lactating women head seborrheic dermatitis in TCM outside governance, the effect was good, safe and non-toxic side effects, and the recurrence rate is low.%  目的:探讨中药外洗治疗哺乳期妇女头部脂溢性皮炎的疗效及护理体会。方法:对120例哺乳期妇女效脂溢性皮炎患者应用中药外洗治疗。结果:120例患者全部治愈。结论:中药外洗治疗疗哺乳期妇女效脂溢性皮炎疗效好,安全无毒副作用,复发率低。

  6. Clinical observation of Xiangbai Shampoo in treating 71 cases of seborrheic dermatitis of scalp%香柏波治疗头部脂溢性皮炎71例临床观察

    Institute of Scientific and Technical Information of China (English)

    陈雪燕; 蔡玲玲; 张历元; 贾苑凝; 姜晓媛; 李元文

    2016-01-01

    Objective: To observe the curative effect and security of Xiangbai Shampoo in treating seborrheic dermatitis of scalp (SDS). Method: The patients with SDS (n=71) were chosen in accord with diagnostic and inclusion criteria, and then they were divided randomly into the treatment group (n=36) and the control group (n=35). The treatment group was treated with Xiangbai Shampoo while the control group was treated with 2 % of ketoconazolelotion (Triatop Lotion produced by Xi`an Janssen Pharmaceutica Ltd.). The treatment and observation lasted 4 weeks and the curative effect was compared and summed up. Results: The treatment group (77.8%) and the control group (62.9%) had no significant difference in the total effective rate, but the treatment group (41.7%) had much better markedly effective and cure rate than the control group (17.1%). In the treatment group, the curative effects of erythema, dandruff, seborrhea, itching and lesion area were almost similar to those in the control group. Conclusion:Xiangbai Shampoo was an effective and safe preparation fin treating seborrheic dermatitis of scalp.%目的:观察香柏波治疗脂溢性皮炎的临床疗效和安全性。方法:选取符合诊断标准及纳入标准的头皮脂溢性皮炎患者71例,采用阳性药物随机对照的研究方法,治疗组(36例)使用自制香柏波,对照组(35例)使用2%酮康唑洗剂(采乐,西安杨森公司生产),治疗观察4周,总结比较疗效。结果:治疗组总有效率77.8%,愈显率41.7%,对照组总有效率62.9%,愈显率为17.1%,两组总有效率经统计无明显差异,而治疗组愈显率显著高于对照组,治疗组在红斑、鳞屑、脂溢、瘙痒症状及皮损面积改善方面的疗效基本上与对照组相仿。结论:香柏波治疗头部脂溢性皮炎安全有效。

  7. Feline herpesvirus 1-associated facial and nasal dermatitis and stomatitis in domestic cats.

    Science.gov (United States)

    Hargis, A M; Ginn, P E

    1999-11-01

    Feline herpesvirus-associated dermatitis has rarely been reported. Recently we documented a unique ulcerative and often persistent facial dermatitis or stomatitis syndrome associated with feline herpesvirus 1. We believe this syndrome is relatively common, with the 10 cases in our series diagnosed between 1996 and 1997. The syndrome is associated with epithelial cell necrosis, eosinophilic inflammation, and intraepithelial herpesvirus inclusion bodies. The prevalence of eosinophilic inflammation and low number of inclusion bodies may lead to the misdiagnosis of allergic dermatitis or a lesion within the eosinophilic granuloma complex group of disorders. Feline herpesvirus 1 can be identified in lesional tissue by PCR methodology. Most of our cases developed under circumstances suggesting reactivation of latent herpesvirus infection, and previous glucocorticoid therapy or stress from overcrowding may have played a role in lesion development. Cats with ulcerative dermatitis, especially of the face and nose, and cats with stomatitis should be evaluated for the presence of feline herpesvirus. Treatment options include surgical excision, topical or systemic antibiotic therapy to treat secondary bacterial infection, and oral alpha interferon.

  8. Studying of a wave activity condition and cellular metabolism of tissues in patients with perioral dermatitis

    Directory of Open Access Journals (Sweden)

    Grashkin V.A.

    2012-06-01

    Full Text Available

    Perioral dermatitis is a facial skin disease with insuffciently studied ethiology and pathogenetic mechanisms, being one of actual problems of dermatology. It is a chronic relapsing facial skin disease mainly in women of young and middle age (in men and children meets less often. The disease has an independent clinical picture which is different from rosacea, demodecosis, seborrheic dermatitis, etc. The standard diagnostic criterion is a visual estimation of expression of an infammation on the basis of signs of exudative reaction which has a subjective character. Possibilities of a radiometric method for an objective estimation of a facial skin functional condition and indicators of an intracellular metabolism in patients with a perioral dermatitis were frst studied.

  9. Demodex dermatitis: a retrospective analysis of clinical diagnosis and successful treatment with topical crotamiton.

    Science.gov (United States)

    Bikowski, Joseph B; Del Rosso, James Q

    2009-01-01

    Given the reported common occurrence of Demodex dermatitis in the general population, Demodex dermatitis-considered as a separate condition from rosacea and seborrheic dermatitis-was evaluated in a retrospective case analysis.

  10. 维胺酯胶囊治疗脂溢性皮炎安全性及可行性分析%The safety and feasibility analysis of viaminate capsule in the treatment of seborrheic dermatitis

    Institute of Scientific and Technical Information of China (English)

    李艳伟

    2014-01-01

    目的:探讨维胺酯胶囊治疗脂溢性皮炎及可行性分析安全性。方法根据数字表法将84例脂溢性皮炎患者随机分为观察组和对照组,各42例,对照组患者给予1%吡美莫司乳膏外涂,2次/d;观察组在对照组基础上口服维胺酯胶囊50 mg/次,2次/d,2周为1个疗程,连续用药2个疗程。观察两组患者疗效和不良反应。结果观察组治疗4周、8周后红斑、鳞屑、皮脂溢、瘙痒等症状积分及总积分显著低于对照组(红斑t=5.865、5.786,鳞屑t=6.112、5.886,皮脂溢t=5.963、5.629,瘙痒t=6.123、6.072,均P<0.05)。观察组治疗1周、4周、8周总有效率分别为57.14%、85.71%、95.24%,对照组分别为42.86%、59.52%、80.95%,差异均有统计学意义(χ2=5.632、6.986、5.252,均P<0.05)。观察组复发率为2.38%,低于对照组的19.05%;满意率100.00%,高于对照组的76.19%,差异均有统计学意义(χ2=5.986、6.123,均P<0.05)。而两组不良反应发生率差异无统计学意义(χ2=0.589,P>0.05)。结论维胺酯胶囊能在较短的时间内改善脂溢性皮炎患者临床症状,效果显著,复发率低,安全有效。%Objective To investigate the safety and feasibility of viaminate capsule in the treatment of sebor-rheic dermatitis.Methods According to the digital table, 84 patients with seborrheic dermatitis were randomly divided into the observation group(n=42) and the control group(n=42).The control group were treated with 1%pimecrolimus cream coated, 2 times/d.The observation group were treated with capsule viaminate, 50mg/times, 2 times/d,2 weeks for a course of treatment.The clinical efficacy of the two groups were observed.Results The ery thema,scaling,seborrhea,itching and other symptoms score and total score after treatment to 4 weeks,8 weeks of the two groups were compared

  11. Childhood granulomatous periorificial dermatitis in children with extra-facial involvement

    Directory of Open Access Journals (Sweden)

    Rameshwar Gutte

    2011-01-01

    Full Text Available Childhood granulomatous periorificial dermatitis (CGPD is a self-limiting and well-recognized entity. A six-year-old male child, a known case of juvenile rheumatoid arthritis (JRA presented with multiple red raised and yellowish lesions over the face, neck, trunk and upper extremities since one month with occasional itching. Cutaneous examination revealed multiple erythematous scaly papules of size up to 5 mm around the mouth, nose and periorbital areas, neck, trunk and upper extremities with few excoriations. Lesional skin biopsy was pathognomic of CGPD. We report a six-year-old Indian male child with extra-facial involvement and healing with small atrophic pigmented scars in a known case of JRA.

  12. Facial dermatosis associated with Demodex: a case-control study

    Institute of Scientific and Technical Information of China (English)

    Ya-e ZHAO; Yah PENG; Xiang-lan WANG; Li-ping WU; Mei WANG; Hu-ling YAN; Sheng-xiang XIAO

    2011-01-01

    Demodex has been considered to be related with multiple skin disorders,but controversy persists.In this case-control study,a survey was conducted with 860 dermatosis patients aged 12 to 84 years in Xi'an,China to identify the association between facial dermatosis and Demodex.Amongst the patients,539 suffered from facial dermatosis and 321 suffered from non-facial dermatosis.Demodex mites were sampled and examined using the skin pressurization method.Multivariate regression analysis was applied to analyze the association between facial dermatosis and Demodex infestation,and to identify the risk factors of Demodex infestation.The results showed that total detection rate of Demodex was 43.0%.Patients aged above 30 years had higher odds of Demodex infestation than those under 30 years.Compared to patients with neutral skin,patients with mixed,oily,or dry skin were more likely to be infested with Demodex (odds ratios (ORs) were 2.5,2.4,and 1.6,respectively).Moreover,Demodex infestation was found to be statistically associated with rosacea (OR=8.1),steroid-induced dermatitis (OR=2.7),seborrheic dermatitis (OR=2.2),and primary irritation dermatitis (OR=2.1).In particular,ORs calculated from the severe infestation (≥5 mites/cm2) rate were significantly higher than those of the total rate.Therefore,we concluded that Demodex is associated with rosacea,steroid-induced dermatitis,seborrheic dermatitis,and primary irritation dermatitis.The rate of severe infestation is found to be more correlated with various dermatosis than the total infestation rate.The risk factors of Demodex infestation,age,and skin types were identified.Our study also suggested that good hygiene practice might reduce the chances of demodicosis and Demodex infestation.

  13. Facial dermatosis associated with Demodex: a case-control study.

    Science.gov (United States)

    Zhao, Ya-e; Peng, Yan; Wang, Xiang-lan; Wu, Li-ping; Wang, Mei; Yan, Hu-ling; Xiao, Sheng-xiang

    2011-12-01

    Demodex has been considered to be related with multiple skin disorders, but controversy persists. In this case-control study, a survey was conducted with 860 dermatosis patients aged 12 to 84 years in Xi'an, China to identify the association between facial dermatosis and Demodex. Amongst the patients, 539 suffered from facial dermatosis and 321 suffered from non-facial dermatosis. Demodex mites were sampled and examined using the skin pressurization method. Multivariate regression analysis was applied to analyze the association between facial dermatosis and Demodex infestation, and to identify the risk factors of Demodex infestation. The results showed that total detection rate of Demodex was 43.0%. Patients aged above 30 years had higher odds of Demodex infestation than those under 30 years. Compared to patients with neutral skin, patients with mixed, oily, or dry skin were more likely to be infested with Demodex (odds ratios (ORs) were 2.5, 2.4, and 1.6, respectively). Moreover, Demodex infestation was found to be statistically associated with rosacea (OR=8.1), steroid-induced dermatitis (OR=2.7), seborrheic dermatitis (OR=2.2), and primary irritation dermatitis (OR=2.1). In particular, ORs calculated from the severe infestation (≥5 mites/cm(2)) rate were significantly higher than those of the total rate. Therefore, we concluded that Demodex is associated with rosacea, steroid-induced dermatitis, seborrheic dermatitis, and primary irritation dermatitis. The rate of severe infestation is found to be more correlated with various dermatosis than the total infestation rate. The risk factors of Demodex infestation, age, and skin types were identified. Our study also suggested that good hygiene practice might reduce the chances of demodicosis and Demodex infestation.

  14. Bacillus cereus strain isolated from Demodex folliculorum in patients with topical steroid-induced rosaceiform facial dermatitis.

    Science.gov (United States)

    Tatu, Alin Laurentiu; Ionescu, Marius Anton; Clatici, Victor Gabriel; Cristea, Violeta Corina

    2016-01-01

    The aim of the study was to identify Bacillus species from the Demodex folliculorum of patients with topical steroidinduced facial rosaceiform dermatitis. Of the 75 patients examined, 20% had clinical spinulosis, while 18.66% had dermoscopic features of Demodex: follicular plugs and tails. Of the 17.33% positive patients identified upon microscopy for Demodex, samples for bacterial culture were plated on trypticase soy Colombia agar. Identification was performed by microorganisms grown method mass spectrometry. We identified a strain of Bacillus cereus.

  15. [Clinical effectiveness and tolerance of climbazole containing dandruff shampoo in patients with seborrheic scalp eczema].

    Science.gov (United States)

    Wigger-Alberti, W; Kluge, K; Elsner, P

    2001-08-16

    Pityrosporum ovale appears to play an important role in the pathogenesis of dandruff as a symptom of seborrheic dermatitis. Climbazole is an antimycotic agent with a high in vitro and in vivo efficacy against P. ovale. In the presented work we investigated the efficacy and safety of a climbazole 0.65% shampoo on seborrheic dermatitis of 30 volunteers. Subjects were diagnosed as having moderate to severe seborrheic dermatitis of the scalp. After a 1-week washout and a 4-week treatment the clinical evaluation showed a successful reduction of dandruff, skin redness and itching in 80% of the volunteers and a mild improvement in 20% of the volunteers. The cosmetic acceptability was very good by the majority. It is concluded that the formulation tested is effective in the treatment of moderate to severe dandruff.

  16. 自制槿柏洗剂治疗头皮脂溢性皮炎的研究%Study on treatment of seborrheic dermatitis of scalp by homemade Jin Bai Lotion

    Institute of Scientific and Technical Information of China (English)

    付蓉; 李元文; 周志强; 张丰川; 赵凤珠

    2015-01-01

    Objective It is to observe the clinical curative effect of homemade Jin Bai lotion ( JBL) in treatment of sebor-rheic dermatitis of scalp ( SDS) .Methods 210 patients with SDS by clinical diagnosis were selected and randomly divided into experimental group with 106 cases and control group with 104 cases.The patients were treated with JBL in the experimental group and 2%Ketoconazole Lotion in the control group.The symptom score before the treatment and after 2 weeks, 4 weeks of treatment were evaluated, and the clinical curative effect were observed.Results The symptom scores of erythema, scales, itching, seborrhea and skin lesions after treatment for 2 weeks and 4 weeks were markedly improved than before treatment in the both groups ( all P<0.05) , and the improvement in the experimental group were significantly better than that in the con-trol group (all P<0.05).The total effective rates of symptom improvement for erythema, scales, itching, seborrhea and skin lesions after treatment for 2 weeks and 4 weeks in the experimental group were markedly higher than those in the control group ( all P<0.05).The comprehensive effect rate of the experimental group were significantly higher than that of the control group (P<0.05).There were no serious adverse reactions in the both groups.Conclusion JBL is a topical Chinese medicine prep-aration for treating SDS with higher effect and safety, so it is worthy of further clinical application.%目的:观察槿柏洗剂治疗头皮脂溢性皮炎的临床疗效。方法将头皮脂溢性皮炎患者随机分为试验组和对照组,试验组使用自制槿柏洗剂治疗,对照组使用2%酮康唑洗剂治疗。观察2组治疗前及治疗2周、4周时的症状积分及临床疗效。结果2组治疗2周、4周时红斑、脂溢、鳞屑、瘙痒及皮损面积症状评分均较治疗前明显改善(P均<0.05),且试验组改善情况明显优于对照组(P均<0.05);治疗2周、4周时试验组红斑

  17. Bacillus cereus strain isolated from Demodex folliculorum in patients with topical steroid-induced rosaceiform facial dermatitis*

    Science.gov (United States)

    Tatu, Alin Laurentiu; Ionescu, Marius Anton; Clatici, Victor Gabriel; Cristea, Violeta Corina

    2016-01-01

    The aim of the study was to identify Bacillus species from the Demodex folliculorum of patients with topical steroidinduced facial rosaceiform dermatitis. Of the 75 patients examined, 20% had clinical spinulosis, while 18.66% had dermoscopic features of Demodex: follicular plugs and tails. Of the 17.33% positive patients identified upon microscopy for Demodex, samples for bacterial culture were plated on trypticase soy Colombia agar. Identification was performed by microorganisms grown method mass spectrometry. We identified a strain of Bacillus cereus. PMID:27828651

  18. Severe facial dermatitis as a late complication of aesthetic rhinoplasty; a case report

    Directory of Open Access Journals (Sweden)

    Sodaify Manoochehr

    2004-03-01

    Full Text Available Abstract Background Contact dermatitis, as a cutaneous complication after rhinoplasty, is of early onset, limited and transient. The cause of this dermatitis is irritant or allergic. Late onset skin complications are rare and non-inflammatory. Case presentation We are reporting an unexpected, severe allergic contact dermatitis of the face, in a young female, appearing one month following aesthetic rhinoplasty. She failed to respond to ordinary treatments for dermatitis. We did standard battery – including nitrofurazone, tincture of benzoin and hydrocortisone – patch test for the patient that showed sensitivity to benzoin and corticosteroid. Conclusions In summary we report a case of a severe allergic contact dermatitis of the face, in a 21-year-old girl who underwent corrective aesthetic rhinoplasty, appearing one month following surgical operation. We were unable to find a similar report in the medical literature.

  19. Facial contact dermatitis and the irritant potential of mobile phone screens.

    Science.gov (United States)

    Valdivieso, Rommel; Heras-Mendaza, Felipe; Conde-Salazar, Luis

    2013-01-01

    A teenager with atopic dermatitis presented with a 12-month history of recurrent, pruritic, round and polygonal patches on her face. Patch tests using the European standard series (including nickel, chromium, and cobalt chloride), a plastic and glue series of allergens, polyester components, and personal and environmental products in contact with the patient were conducted. For the patient and 3 of 14 healthy volunteers, positive reactions were observed to the patient's mobile phone touchscreen (TS), an extract solution from the TS, and a non-TS phone of another brand. Accordingly, the patient's dermatitis disappeared when contact with mobile phone screens was avoided.

  20. Analysis on the triggering factors of pityriasis versicolor, Malassezia folliculitis and seborrheic dermatitis%花斑癣、马拉色菌毛囊炎、脂溢性皮炎马拉色菌诱发因素分析

    Institute of Scientific and Technical Information of China (English)

    许雪; 李红宾; 黄云丽; 李玉叶; 董天祥; 林松发; 程露

    2014-01-01

    Objective To investigate the triggering factors of pityriasis versicolor , Malassezia folliculitis and seb-orrheic dermatitis.Methods Survey among the patients with pityriasis versicolor, Malassezia folliculitis or seborrheic dermatitis was performed by questionnaire.Results Of the 158 patients, there were 104 males and 54 females, aged 29.4 years.The proportion of patients with hyperidrosis and oily skin is more than 60%.Systemic or topical applica-tion of corticosteroids was the main risk factor of Malassezia folliculitis.Conclusion Malassezia infection was com-mon in young adults.Pityriasis vesicolor was common in patient with hyperidrosis.The oily skin and application of corticosteroids were the main triggering factor of Malassezia folliculitis.%目的调查昆明地区花斑癣、马拉色菌毛囊炎、脂溢性皮炎马拉色菌诱发因素,并比较三种疾病的诱发因素有无差异。方法收集花斑癣、马拉色菌毛囊炎、脂溢性皮炎(头皮屑)的病例,用自制的调查表对入选病例进行诱发因素调查,比较诱发因素在三种疾病间有无差异。结果共收集158例病例,男104例,女54例,平均年龄29.4岁,多汗、油性皮肤患者所占比例均超过60%,系统或局部使用糖皮质激素是马拉色菌毛囊炎的危险因素。结论马拉色菌感染好发于男性青壮年,多汗者易发生花斑癣,油性皮肤及使用糖皮质激素易发生马拉色菌毛囊炎。

  1. Dermatofibroma simulating seborrheic keratosis dermoscopically*

    Science.gov (United States)

    Barroso, Daniel Holanda; Leite, Camila Pinon Zoby; Araujo, Gabriela Diniz de Souza; Teixeira, Márcia Almeida Galvão; Alencar, Eliane Ruth Barbosa; Cavalcanti, Silvana Maria de Morais

    2016-01-01

    Dermatofibroma is a frequent benign tumor of easy clinical diagnosis in most cases, but that can mimic other dermatoses. Dermoscopy may help to define the diagnosis and its classical pattern is a central white area, similar to a scar, surrounded by a discrete pigment network. However, dermoscopic findings are not always typical. We describe here a case of dermatofibroma exhibiting ridges, furrows and pseudocomedos, a pattern which is typical of seborrheic keratosis, in dermoscopy. PMID:27438205

  2. Demodex Dermatitis: A Retrospective Analysis of Clinical Diagnosis and Successful Treatment with Topical Crotamiton

    OpenAIRE

    Bikowski, Joseph B.; Del Rosso, James Q.

    2009-01-01

    Given the reported common occurrence of Demodex dermatitis in the general population, Demodex dermatitis—considered as a separate condition from rosacea and seborrheic dermatitis—was evaluated in a retrospective case analysis.

  3. Demodex Dermatitis: A Retrospective Analysis of Clinical Diagnosis and Successful Treatment with Topical Crotamiton

    OpenAIRE

    Bikowski, Joseph B.; Del Rosso, James Q.

    2009-01-01

    Given the reported common occurrence of Demodex dermatitis in the general population, Demodex dermatitis—considered as a separate condition from rosacea and seborrheic dermatitis—was evaluated in a retrospective case analysis.

  4. Contact dermatitis

    Science.gov (United States)

    Dermatitis - contact; Allergic dermatitis; Dermatitis - allergic; Irritant contact dermatitis; Skin rash - contact dermatitis ... There are 2 types of contact dermatitis. Irritant dermatitis: This ... with acids, alkaline materials such as soaps and detergents , ...

  5. Eruptive seborrheic keratoses associated with adalimumab use.

    Science.gov (United States)

    Eastman, Kristin L; Knezevich, Stevan R; Raugi, Gregory J

    2013-06-30

    Seborrheic keratoses are common, benign cutaneous growths, however in rare situations they can acutely erupt in large numbers. Eruptive seborrheic keratoses can be associated with internal malignancy (sign of Leser-Trelat), but may also appear in conjunction with inflammatory dermatoses and adverse drug reactions. A 71-year-old Caucasian man presented with acute onset of a pruritic, burning papular erythematous rash on his chest, upper extremities and lower extremities after a routine adalimumab injection for rheumatoid arthritis. Two skin biopsies obtained showed findings diagnostic of seborrheic keratoses. Spontaneous resolution of the diffuse eruptive seborrheic keratoses was achieved within 3 months of discontinuing adalimumab therapy. We believe the development of eruptive seborrheic keratoses due to adalimumab therapy is rare, and because our patient responded promptly to discontinuation of the drug we suggest this should be the preferred course of action in future cases.

  6. Facial hormone-dependent dermatitis: a clinical analysis of 68 cases%面部激素依赖性皮炎临床分析及其治疗效果

    Institute of Scientific and Technical Information of China (English)

    黄静

    2010-01-01

    Objective To explore the incidence of facial hormone-dependent dermatitis, and to raise the healing rate of it. Methods We applied non-steroid drug topically, cold compress combined with anti-histamine agents to treat facial hormone-dependent dermatitis in 68 cases. The results were compared before and after the treatment. Results There were significantly clinical effects of non-steroid drug topically, cold compress combined with antihistamine agents on facial hormone-dependent dermatitis, with healing rate of 82. 4 % , and effective rate of 100 %. Conclusions In order to reduce the incidence of facial hormone-dependent dermatitis, we should follow the principal of applying steroid agent strictly to treat facial dermatitis. Meanwhile, there is significantly clinical effects of non-steroid drug with topical use and cold compress combined with antihistamine agents on facial steroid-dependent dermatitis.%目的 探讨减少面部激素依赖性皮炎的发生率和提高治愈率.方法 对68例面部激素依赖性皮炎治疗采用外用冷敷收敛联合内服抗组胺药,并对治疗效果进行对比分析.结果 采用外用、冷敷收敛联合抗组胺药取得满意疗效,痊愈率82.4%,有效率100%.结论 在使用糖皮质激素时,应严格掌握外用药物使用原则,减少面部激素依赖性皮炎的发生.采取内服、外用药物的综合治疗方法 ,对面部激素依赖性皮炎可以取得较好的临床疗效.

  7. Clinical efficacy of collagen posted dressing in treatment of facial dermatitis%胶原贴敷料治疗面部皮炎疗效观察

    Institute of Scientific and Technical Information of China (English)

    华伟; 米新陵; 李凡; 严霞

    2011-01-01

    目的:观察胶原贴敷料在治疗面部皮炎中的安全性和临床疗效.方法:160例患者分为两组,治疗组89例,胶原贴敷料每天1次湿敷,氦氖激光照射每天1次;对照组71例,仅氦氖激光照射每日1次.两组均给予口服依巴斯汀10mg/天,赛庚啶片2mg/次,3次/天.2周为1个疗程,1个疗程后观察两组治疗效果和不良反应.结果:2周后治疗组和对照组有效率分别为88.76%和66.20%,两组差异有统计学意义(x2=12.01,P<0.05).结论:联合胶原贴敷料治疗面部皮炎疗效好,无明显不良反应,值得临床选择应用.%Objective To evaluate the efficacy and safety of the posted collagen dressing in the treatment of facial dermatitis. Methods 160 patients with facial dermatitis were divided into two groups. All patients applied cyproheptadine Take three doses a day and Ebastine once a day.The treatment group 89 cases were treated with helium neon laser once a day. In addition treated with Collagen posted dressing once a day. The control group 71 cases were treated with helium neon laser once a day. The follow-up was 2 weeks from the end of the treatment. The clinical response to therapy and adverse effects were recorded. Results The effective rate was 88.76% in the treatment group. The effective rate was 66.20% in the control group.The comparison in two groups showed significant differences (x2=12.01,P<0.05). Conclusion Collagen posted dressing in treatment of facial dermatitis is effective, safe and suggest new therapeutic opportunities for treating this disease

  8. Effect of microscopic XL-radiofrequency ablation on head-facial papulosa nigra and lichenoid seborrheic keratosis%手术显微镜下XL-射频皮肤治疗仪祛除头面部黑色丘疹及苔藓样脂溢性角化

    Institute of Scientific and Technical Information of China (English)

    王兴林; 孙玉萍; 蒋天裕; 张立宁; 高月明; 黄丽萍; 肖红雨; 张茜

    2013-01-01

    Objective To observe the effect of microscopic XL-radiofrequency ablation on head-facial papulosa nigra and lichenoid seborrheic keratosis (LSK). Methods Sixty-three patients with head-facial papulosa nigra and LSK (32 males, 31 females) at the age of 35-81 years who visited our outpatient department from April 2008 to October 2011 were included in this study. The course of their disease was 6 months-40 years. The number of lesions was 274 with a minimal size of 4 mm×3 mm and a maximal size of 30 mm×25 mm. The diameter of 42 lesions was > 10 mm. Five lesions were located in the vertex and temple while the rest were located on the face. The lesions were treated once with microscopic XL-radiofrequency ablation. The patients were followed up for 6 months-2 years. Results Of the 274 lesions in 63 patients, 268 were cured with an excellent effect for 6 lesions and mild depigmentation in 1 lesion. No scar formation was found. Conclusion Microscopic XL-radiofrequency ablation shows a high curative rate for papulosa nigra and LSK with no scar formation.%  目的观察手术显微镜下XL-射频皮肤治疗仪消融祛除头面部黑色丘疹样及苔藓样脂溢性角化的疗效。方法2008年4月-2011年10月我院门诊黑色丘疹样及苔藓样病变明显高于周围皮肤患者63例,男32例,女31例,年龄35~81岁,病程6月~40年,病变274个,最小4 mm×3 mm,最大30 mm×25 mm,>10 mm以上42个,位于头顶及颞部毛发处5个,其余位于面部。采用XL-射频皮肤治疗仪治疗1次,随访观察6个月~2年。结果63例274个病变,治愈268个,显效6个,1个有轻微色素脱失,未出现肉眼可见的疤痕。结论显微镜下XL-射频皮肤治疗仪祛除黑色丘疹样及苔藓样脂溢性角化治愈率高,无疤痕。

  9. Expression of T Lymphocyte Subsets in Lesions of Facial Steroid-dependent Dermatitis%面部激素依赖性皮炎皮损中T淋巴细胞亚群的分析

    Institute of Scientific and Technical Information of China (English)

    吴景良; 徐西红; 张理涛

    2013-01-01

    Objective To observe the expression of T lymphocyte subsets in lesions of facial steroid-dependent dermatitis and to explore the pathogenesis.Methods Twenty-five patients with facial steroid-dependent dermatitis and ten patients with facial subacute eczema were diagnosed clinically.Ten healthy skin specimens were taken as controls.The distribution and intensity of expression of T lymphocyte subsets in the specimens were detected by immunohistochemical SP method.Results There was not or little CD4+and CD8+T were detected cell in the superficial dermis of normal skin tissue,but a large number of CD4+and CD8+T cell were expressed at the dermal papilla,superficial dermis in facial subacute eczema and facial steroid-dependent dermatitis.The level of CD8+T cell in facial steroid-dependent dermatitis were higher than that of controls,and there had a significant statistical difference(P<0.017);The level of C D8+T cell in facial subacute eczema were higher than that of controls,and there had a significant statistical difference(P<0.017).The level of CD4+T cell in facial steroid-dependent dermatitis and facial subacute eczema were higher than that of controls,but they hadn't statistically significant difference(P>0.05).Although the CD4+/CD8+ratio in facial steroid-dependent dermatitis increased,compared with controls,there was no statistical difference(P>0.05).Conclusion The change of T lymphocyte subsets in the lesion of facial steroid dependence dermatitis,which maybe participated in immunopathogenesis of facial steroid dependence dermatitis.%目的 探讨T淋巴细胞亚群在面部激素依赖性皮炎发病机制中的作用.方法 应用免疫组织化学SP法检测25例面部激素依赖性皮炎患者皮损、10例面部亚急性湿疹患者皮损、10例外科手术切取的面部外观正常皮肤T淋巴细胞亚群分布特点.结果 正常皮肤组织CD4+,CD8+T细胞在真皮浅层呈阴性或少量表达,面部亚急性湿疹皮损和面部激

  10. Atopic dermatitis

    DEFF Research Database (Denmark)

    Thomsen, Simon Francis

    2014-01-01

    Atopic dermatitis is an inflammatory skin disease with early onset and with a lifetime prevalence of approximately 20%. The aetiology of atopic dermatitis is unknown, but the recent discovery of filaggrin mutations holds promise that the progression of atopic dermatitis to asthma in later childhood...... may be halted. Atopic dermatitis is not always easily manageable and every physician should be familiar with the fundamental aspects of treatment. This paper gives an overview of the natural history, clinical features, and treatment of atopic dermatitis....

  11. 面部不明原因皮炎接触过敏原分析%Analysis of Contact Allergic Substances in 106 Facial Dermatitis Patients with Unconfirmed Reason

    Institute of Scientific and Technical Information of China (English)

    刘蔚; 胡白; 张兰芳; 姚秀华

    2013-01-01

    目的 对面部不明原因皮炎患者的接触过敏物质进行分析.方法 对106例面部不明原因皮炎患者进行中国筛查系列斑贴试验,对其中20例可疑的化妆品致敏患者进行化妆品系列斑贴试验,按照国际接触性皮炎研究组推荐的标准为依据.结果 中国筛查系列斑贴试验总阳性率54.72%,阳性率较高的前5位变应原是硫酸镍(18.87%)、甲醛(13.21%)、5-氯-2-甲基-4-异噻唑啉-3-酮(CL+Me-异噻唑)(12.26%)、氯化钴(9.43%)和芳香混合物(8.49%).化妆品系列斑贴试验总阳性率100%,阳性率较高的前3位变应原是山梨糖醇酐倍半油酸酯(司盘-83)(40.00%)、月桂醇葡萄苷(30%)和十二烷酸盐(25%).结论 面部不明原因皮炎患者多数存在接触过敏原,中国筛查系列的斑贴试验结果反映该类群体普遍存在体质敏感的现象;化妆品相关变应原的斑贴试验结果显示此类患者主要对乳化剂、表面活性剂、抗氧化剂原料过敏.%Objective To analyze the contact allergic substances in unconfirmed facial dermatitis patients.Methods Patch tests with Chinese standardized patch test technique was used to investigate 106 patients with unknown cause of facial dermatitis.Among them,20 patients with suspicious cosmetic contact dermatitis were further tested with cosmetic related allergens,following the recommended standard of the International Contact Dermatitis Research Group.Results The positive rate of Chinese standardized patch test technique was 54.72%.The top five allergens were nickel sulphate (18.87%),formaldehyde (13.21%),CL+Me-isothiazole (12.26%),cobalt chloride (9.43%) and aromatic compounds (8.49%).The positive rate of standardized patch test technique cosmetic patch tests was 100%.The top three allergens were Span-83 (40.00%),lauryl monophosphate grapes(30%) and lauric acid salt(25%).Conclusion The results of patch tests in unconfirmed facial dermatitis patients are

  12. 季节性接触性面部皮炎的变应原皮试及免疫疗效分析%Analysis on allergen skin test and immunotherapy efficacy of seasonal contact facial dermatitis

    Institute of Scientific and Technical Information of China (English)

    许卫华

    2014-01-01

    Objective To explore the allergen skin test and immunotherapy efficacy of seasonal contact facial dermati-tis. Methods A retrospective analysis was conducted on the clinical data of 87 patients with facial dermatitis admitted and treated at the Department of Dermatology in our hospital from December 2009 to December 2011.Experimental al-lergen extract prepared by the allergic reaction lab of the Department of Dermatology was selected as the antigen,in-cluding 16 inhalants in total.All the patients stopped application of cortical hormone and antihistamine drug 3 d before the skin test.All the patients were prepared for the allergen skin test and the immunotherapy efficacy was observed. Re-sults In 87 patients,65 patients had positive reaction to one or multiple allergens.Positive allergen was consistent with the onset season among 58 patients.Immunotherapy resulted in 33 cases of cure,27 cases of significant therapeutic ef-fect,17 cases of therapeutic effect and 10 cases without therapeutic effect,with total significant effective rate of 68.96%and total effective rate of 88.50%. Conclusion Pollen antigen is the main pathogenic factor of seasonal facial dermatitis in spring and autumn.The incidence of facial dermatitis is consistent with the positive rate of seasonal allergen.Im-munotherapy has significant efficacy,which is worthy of widespread clinical application and promotion.%目的:探究季节性接触性面部皮炎的变应原皮试及免疫疗效。方法对本院2009年12月~2011年12月皮肤科收治的87例面部皮炎患者的临床资料进行回顾性分析,选择本院皮肤科变态反应室制备实验变应原浸液为抗原,共有16种吸入物,于皮试前3 d,所有患者均停用皮质激素以及抗组胺药物,予以患者变应原皮试处理,观察患者的免疫效果。结果87例患者,65例患者均对同一种或者多种变应原呈阳性反应,其中阳性致敏变应原与发病季节吻合患者58例,

  13. 166例面部皮炎患者临床及致病因素分析%Preliminary analysis of the clinical features and etiological factors of facial dermatitis

    Institute of Scientific and Technical Information of China (English)

    曲燕; 孟现广; 杨秀莉

    2016-01-01

    对166例面部皮炎患者进行问卷调查,部分患者行皮肤斑贴试验与点刺试验。其中,女性(138例)多于男性(28例),年龄2~89岁,平均(30±12)岁;春季发病率为3.85%,高于夏季(0.56%)、秋季(0.84%)和冬季(3.33%);接触性皮炎与激素依赖性皮炎是面部皮炎最常见的类型,分别占30.7%和21.1%;皮肤斑贴试验和点刺试验的阳性率分别为69.05%、72.22%,是寻找致敏原的有效方法。%Questionnaire survey of clinical features and the etiological factors was performed in 166 pa-tients with facial dermatitis (FD). 130 patients were female, and 28 patients were male. The patients aged from 2 to 89 years old and the average age was ( 30 ± 12) years old. The incidence rate in the spring was 3.85%, which was higher than that in summer ( 0. 56%) , autumn ( 0. 84%) and winter ( 3. 33%) . Contact dermatitis (30.7%) and hormone dependent dermatitis (21.1%) were common types. Positive rates of PT and SPT were 69.05% and 72.22%, which were effective methods to find the allergens.

  14. 疑似面部化妆品变应性接触性皮炎58例斑贴试验%The Patch Test Results of 58 Cases of Suspected Facial Cosmetic Allergic Contact Dermatitis

    Institute of Scientific and Technical Information of China (English)

    郑结成; 徐宁; 张杰; 周静; 窦侠; 于波

    2016-01-01

    Objective To investigate cosmetic products related allergens and provide clinical guidance for suspected facial cosmetic allergic contact dermatitis patients.Methods Patch test of cosmetic series allergens was performed on 58 patients with suspected cosmetic allergic contact dermatitis.Thirty-seven patients were also tested by European standard series allergens at the same time.The positive reactions were determined according to the international contact dermatitis research group recommendation.Results Of the 58 patients patch test with cosmetic series, 34 (58.62%) patients showed at least one positive reaction.The most common allergen was Kathon CG (31.03%), which belonged to preservative allergens.Of the 37 patients patch test by European standard series allergens, 24 (64.86%) showed positive reactions.Conclusion Preservatives including Kathon CG, Methylisothiazolinone are the most common allergens inducing the cosmetic allergic contact dermatitis.%目的 调查化妆品相关变应原,为疑诊化妆品变应性接触性皮炎的患者进行临床治疗指导及预防.方法 对来自本科门诊的58例疑诊化妆品接触性皮炎患者进行化妆品系列变应原斑贴试验,部分患者同时进行欧洲标准系列变应原斑贴试验,按国际接触性皮炎研究组推荐标准判读结果.结果 58例患者中,化妆品系列斑贴试验阳性率58.62%,最常见的化妆品变应原为卡松CG(31.03%)及甲基异噻唑啉酮(29.31%),在所有的阳性反应中,防腐剂类变应原所占比例最高,为77.59%;欧洲标准系列的化妆品相关变应原中阳性率最高的为卡松CG(21.62%),标准系列中化妆品相关变应原与化妆品系列变应原阳性结果呈中等一致性.结论 防腐剂类是化妆品变应性接触性皮炎患者最主要的过敏原.

  15. Dr. Yu Wenqiu's Experience in Treating Seborrheic Alopecia

    Institute of Scientific and Technical Information of China (English)

    Ding Xiongfei

    2007-01-01

    @@ In China, the occurrence of seborrheic alopecia is on the rise. Chief physician Yu Wenqiu, by combining the rich experience obtained by physicians at all times with his own long-term clinical practice, has developed Shenying Yihao Shengfa Tang and Shenying Erhao Shengfa Tang(神应Ⅰ号生发汤Decoction for Hair Growth No.Ⅰand 神应Ⅱ号生发汤 Decoction for Hair Growth No. Ⅱ), which have yielded very good therapeutic effects for seborrheic alopecia. Following is an introduction to his experience in this aspect.

  16. Detection of feline herpes virus 1 via polymerase chain reaction and immunohistochemistry in cats with ulcerative facial dermatitis, eosinophilic granuloma complex reaction patterns and mosquito bite hypersensitivity.

    Science.gov (United States)

    Persico, Paola; Roccabianca, Paola; Corona, Antonio; Vercelli, Antonella; Cornegliani, Luisa

    2011-12-01

    Ulcerative dermatitis caused by feline herpes virus 1 (FHV-1) is an uncommon disease characterized by cutaneous ulcers secondary to epidermal, adnexal and dermal necrosis. Differential diagnoses for FHV-1 lesions include, but are not limited to, mosquito bite hypersensitivity and eosinophilic granuloma complex. Histopathological diagnosis of FHV-1 dermatitis is based on the detection of the intranuclear inclusion bodies. In cases where intranuclear inclusions are missing but clinical and histological findings are compatible with FHV-1 dermatitis, immunohistochemistry (IHC) and PCRs have been used. In this retrospective study, we evaluated the presence of FHV-1 by IHC and PCR in skin biopsies and compared the results of the two tests. Sixty-four skin biopsy specimens from cats with compatible lesions were reviewed and tested via PCR and IHC for evidence of FHV-1. Polymerase chain reaction was positive in 12 of 64 biopsies; PCR and IHC were positive only in two of 64 biopsies, and these cases were considered true positive cases. The higher number of PCR-positive cases was possibly attributed to amplification of viral DNA from a live attenuated vaccination, but a previous FHV-1 infection with subsequent amplification of latently inserted FHV-1 could not be excluded. If clinical signs and histopathology suggest FHV-1 infection in the absence of typical inclusion bodies, IHC is the preferred diagnostic test; PCR may be useful for initial screening, but due to false positives is not sufficient for a definitive diagnosis.

  17. 医用皮肤胶原修复再生功能敷料治疗面部皮炎的疗效观察%Effect of medical skin collagen regeneration functional dressing on facial dermatitis

    Institute of Scientific and Technical Information of China (English)

    刘宏业; 郭书萍; 白莉

    2015-01-01

    目的:观察医用皮肤胶原修复再生功能敷料治疗面部皮炎的疗效。方法选取面部皮炎湿疹患者40例,采用随机数字表法分为两组,每组20例;A 组为试验组,给予口服酮替芬片治疗及外用医用皮肤胶原修复再生功能敷料;B 组为对照组,仅给口服酮替芬片治疗。治疗前及治疗开始后每3天随访1次,疗程15 d。观察两组临床疗效。结果试验组12 d、15 d 痊愈率分别为63.2%、65.0%,高于对照组的5.0%、5.0%,两组治疗后12 d、15 d 痊愈率差异均有统计学意义(χ2=14.83、15.82,均 P <0.01)。结论医用皮肤胶原修复再生功能敷料联合酮替芬片治疗面部皮炎湿疹安全有效。%Objective To observe and evaluate the healing effect of medical skin collagen regeneration func-tional dressing on facial dermatitis.Methods 40 facial dermatitis patients who met the inclusion criteria were ran-domly divided into the observation group(group A)and control group(group B)averagely.Patients of group A were administrated with ketotifen tablets orally and with medical skin collagen regeneration functional dressing externally,while patients of group B were only orally administrated with ketotifen tablets.The total observation period last 15 days with a follow -up once after 2 days for both of the groups.Results The cure rates of group A after 12 day and 15 day were 63.2% and 65%,higher than the cure rates of group B(5.0% and 5.0%).The 12 day and 15 day cure rates of group A were significantly higher than those of group B(χ2 =14.83,15.82,all P <0.01).Conclusion Medical skin collagen regeneration dressing in combination with fexofenadine tablets provide a safe and effective healing func-tion to facial dermatitis.

  18. Q开关Nd:YAG激光治疗面部激素依赖性皮炎临床分析%Clinical efficacy of Q-switched Nd:YAG laser in treatment of facial hor-mone-dependent dermatitis

    Institute of Scientific and Technical Information of China (English)

    莫惠芳; 储开宇; 崔瑞莹; 王键旋; 何嘉超; 岑焕群

    2015-01-01

    目的:观察Q开关Nd:YAG激光治疗面部激素依赖性皮炎的临床疗效。方法将120例患者随机分为两组,对照组予以抗组胺药物、维生素B6口服治疗;治疗组在对照组的基础上加用Q开关Nd:YAG激光照射治疗。结果治疗组患者瘙痒程度、总积分治疗后均低于对照组,治疗组总有效率为86.67%,对照组总有效率为66.67%,两组比较,差异有统计学意义(P<0.05)。结论采用大光斑低能量Q开关Nd:YAG激光1064 nm照射治疗面部激素依赖性皮炎安全有效,是一种值得推荐和尝试的方法。%Objective To observe the clinical curative effect of Q-switch Nd YAG laser on the treatment of facial hormone-dependent dermatitis. Methods Attal of 120 patients were randomly divided into two groups. The control group was orally administered antihistaminic drugs and Vitamin B6. Based on drugs applied to the control group, additional Q-switch NdYAG laser radiation therapy was introduced into the treatment group. Results After the treatment,pru-ritus and total scores of skin lesion in the treatment group were less than the control group. A total effective rate of 86.67 % was achieved in the treatment group, while that was 66.67 % in the control group. The difference between the two groups was statistical significant(P<0.05). Conclusion The treatment of facial hormone-dependent dermatitis with large light-spot and low-energy Q-switch Nd YAG laser 1064 nm radiation therapy is safe and effective. There-fore,it is well worth popularizing and trying.

  19. Observation on Effect of levocetirizine combination with Virgin olive oil on Facial Recurring Dermatitis%左西替利嗪联合初榨橄榄油治疗颜面再发性皮炎疗效观察

    Institute of Scientific and Technical Information of China (English)

    周艳; 牟宽厚; 韩丹; 王莉; 冯利

    2011-01-01

    Objective To study the effect of levocetirizine combined with Virgin olive oil in the treatment of facial recurring dermatitis. Methods All 67 cases were randomized into experimental and control groups, using Virgin olive oil and heparin sodium cream to spread on lesions respectively. All cases were treated with the levocetirizine orally. Results The erythema, dry, itchy, burning in the treatment group alleviated obviously or even disappeared on the 7th day and 14th day compared with the control group, but there were no statistically significant differences between the two groups in terms of effective rates (P>0.05). But the effective rates on the 14th day was significantly higher than that on the 7th day in treatment group (P<0.05). Conclusion Levocetirizine combined with Virgin olive oil in the treatment of facial recurring dermatitis is safe and effective. And two weeks curative effect is better.%目的:评价左西替利嗪联合初榨橄榄油对女性颜面再发性皮炎的疗效。方法:选取67例女性颜面再发性皮炎患者,并随机分组,分别外用初榨橄榄油(实验组)和肝素钠软膏(对照组)治疗,同时口服左西替利嗪胶囊5mg,每日1次。于使用前、首次使用后第1周、第2周进行临床症状及体征评分比较。结果:实验组患者治疗后自觉红斑、干燥、瘙痒、灼痛明显减轻或消失,治疗后第1周、第2周两组比较有效率差异无统计学意义(P>0.05),但实验组第2周有效率明显高于第1周(P<0.05)。结论:左西替利嗪联合初榨橄榄油治疗女性颜面再发性皮炎安全、有效,且2周疗效较好.

  20. Atopic dermatitis

    DEFF Research Database (Denmark)

    Haagerup, Annette; Bjerke, Torbjørn; Schiøtz, Peter Oluf

    2004-01-01

    Atopic dermatitis is one of the most common chronic diseases of childhood and closely related to other clinical manifestations of allergy. The incidence is high and still increasing. The genetic contribution to disease development is substantial and complex. Only recently genetic research has begun...... to focus on this phenotype, and specific susceptibility genes remain to be found. To identify candidate regions holding genes for atopic dermatitis we performed a genome-scan in Danish affected sib-pair families containing sib-pairs matching a phenotype definition of both clinical atopic dermatitis...

  1. Atopic dermatitis

    Science.gov (United States)

    ... Coulson I, eds. Treatment of Skin Disease: Comprehensive Therapeutic Strategies . 4th ed. Philadelphia, PA: Elsevier Saunders; 2014:chap 17. American Academy of Dermatology. Guidelines of care for the management of atopic dermatitis. ...

  2. A Closer Look at Seborrheic Keratoses: Patient Perspectives, Clinical Relevance, Medical Necessity, and Implications for Management.

    Science.gov (United States)

    Del Rosso, James Q

    2017-03-01

    The author sought to discover why seborrheic keratoses that are not symptomatic or clinically suspicious are not considered therapeutically important to most clinicians. The author conducted an office-based, observational study examining how the diagnosis of asymptomatic seborrheic keratoses personally affects patients and what these patients think concerning treatment. Many patients reported being bothered by the diagnosis of seborrheic keratoses, even when told it's not cancerous, and indicated an interest in its treatment. Lack of insurance coverage for the treatment of non-symptomatic seborrheic keratoses may be the primary reason clinicians do not consider seborrheic keratoses therapeutically important, as clinicians often find the discussion of "self payment" with their patients to be awkward. Furthermore, patients may not understand the implications that "lack of medical necessity" may have on their treatment options. The author describes a clinical approach that may better serve patients and clinicians through the compartmentalization of asymptomatic seborrheic keratoses treatment as a cosmetic procedure within the clinical practice model.

  3. Atopic dermatitis: allergic dermatitis or neuroimmune dermatitis?*

    Science.gov (United States)

    Gaspar, Neide Kalil; Aidé, Márcia Kalil

    2016-01-01

    Advances in knowledge of neurocellulars relations have provided new directions in the understanding and treatment of numerous conditions, including atopic dermatitis. It is known that emotional, physical, chemical or biological stimuli can generate more accentuated responses in atopic patients than in non-atopic individuals; however, the complex network of control covered by these influences, especially by neuropeptides and neurotrophins, and their genetic relations, still keep secrets to be revealed. Itching and airway hyperresponsiveness, the main aspects of atopy, are associated with disruption of the neurosensory network activity. Increased epidermal innervation and production of neurotrophins, neuropeptides, cytokines and proteases, in addition to their relations with the sensory receptors in an epidermis with poor lipid mantle, are the aspects currently covered for understanding atopic dermatitis. PMID:27579744

  4. 欧洲标准变应原联合化妆品筛选变应原对女性面部皮炎患者的斑贴试验%Patch testing for selection of cosmetic allergens in female facial dermatitis by European standard of cosmetic allergens

    Institute of Scientific and Technical Information of China (English)

    周成霞; 李薇; 李利

    2009-01-01

    Objective To identify the common allergens of the female patients with facial dermatitis with European standard of cosmetic allergens.Methods Female patients with facial dermatitis were tested with European standard of cosmetic allergens.The reactions to allergens were documented by following the International Contact Dermatitis Research Group recommendations.Results Total 41female patients with facial dermatitis were tested with European standard of cosmetic allergens,themain cosmetic allergens were hexamine(12.20),thimerosal(9.76%),diazolidinyl urea(7.32%)and DMDM hydantoin(7.32%);the main European standard allergens were nickel sulfate(22.20%),formaldehyde(14.63%),4-phenylencdiamine base(9.76%)and fragrance mix (9.76%).Conclusions NickeJ sulfate,formaldehyde,hexamine,thimerosal,4-phenylenediamine base,fragrance mix,diazolidinyl urea and DMDM hydantoin are the main allergens of female patients with facial dermatitis.%目的 采用欧洲标准变应原联合化妆品筛选变应原对女性面部皮炎患者进行斑贴试验,筛查主要致敏原.方法 对门诊女性面部皮炎患者采用化妆品筛选变应原联合欧洲标准变应原进行斑贴试验,按国际接触性皮炎研究组推荐标准判读结果.结果 41例女性患者进行了38种化妆品筛选变应原和26种欧洲标准变应原的斑贴试验.其中阳性率最高的化妆品筛选变应原计有乌洛托品(12.20%)、硫柳汞(9.76%)、双咪唑烷基脲(7.32%)及DMDM海因(7.32%),阳性率最高的欧洲标准变应原计有硫酸镍(22.20%)、甲醛(14.63%)、对苯二胺(9.76%)及香料混合物(9.76%).结论 硫酸镍,甲醛、乌洛托品、硫柳汞、对苯二胺、香料混合物、双咪唑烷基脲、DMDM海因等是女性面部皮炎患者主要致敏原.

  5. Evaluation of skin barrier function in patients with facial acne, eczema, melasma and solar dermatitis and its clinical significance%面部痤疮、湿疹、黄褐斑及日光皮炎皮肤屏障功能评价及其临床意义

    Institute of Scientific and Technical Information of China (English)

    邹菥; 何黎; 杨成; 庞勤

    2013-01-01

    Objective To compare skin barrier function among patients with facial acne,subacute eczema,melasma and solar dermatitis.Methods Three hundred patients,including 80 patients with facial acne,60 subacute facial eczema,80 facial melasma and 60 facial solar dermatitis,as well as 60 healthy controls were recruited in this study.Skin sebum content and transepidermal water loss (TEWL) were measured by a sebmeter and Tewameter TM 210 (Courage and Khazaka,Germany),respectively.Stratum comeum hydration was measured with a Scalar Moisture Checker (Scalar Corporation,Japan).Statistical analysis was carried out using analysis of variance and t test.Results Compared with the healthy controls,patients with facial acne showed increased skin sebum content and TEWL value but decreased stratum corneum hydration (all P < 0.01),and patients with subacute eczema,solar dermatitis and melasma displayed lower sebum content and stratum corneum hydration but higher TEWL value (all P < 0.01).Skin sebum content was significantly higher in patients with facial acne than in patients with subacute eczema,solar dermatitis and melasma ((184.65 ± 83.07) vs.(21.86 ± 18.94),(25.10 ±14.22) and (36.05 ± 32.84) μg/cm2,all P < 0.01),but was similar between the patients with subacute eczema,solar dermatitis and melasma (P > 0.05).In terms of stratum corneum hydration,patients with subacute eczema and solar dermatitis were statistically lower than those with acne and melasma (18.66% ± 7.85% and 20.91% ± 8.05% vs.24.32% ± 8.16% and 28.02% ± 4.67%,all P < 0.01),patients with facial subacute eczema were similar to those with solar dermatitis (P > 0.05),and patients with facial acne were statistically lower than those with melasma (P <0.01).TEWL value was significantly higher in patients with melasma than in patients with acne,solar dermatitis and subacute eczema ((13.80 ± 4.t 3) vs.(20.86 ± 8.78),(22.85 ± 9.84) and (22.48 ± 10.37) μg/m2 h,all P < 0.01),but similar

  6. Dermatitis artefacta

    DEFF Research Database (Denmark)

    Økland, Camilla; Petersen, Niels Erik; Bygum, Anette

    2016-01-01

    Dermatitis artefacta is a self-inflicted skin disease with a multifactorial aetiology. The condition can be a symptom of an underlying psychiatric condition or a sign of psycho-social stressors. This paper gives an updated view on dermatitis artefacta. The majority of the patients have some form...... of psychiatric co-morbidity including depression and anxiety. Many have experienced negative life events such as diseases or deaths. Personality disorders were reported in only two studies. Treatment options besides the acute treatment of the skin were psychotherapy and psychotropic drugs....

  7. A clinical observation of 107 cases of collagen dressing in treatment of facial hormone dependent dermatitis%107例胶原帖敷料治疗面部激素依赖性皮炎的疗效观察

    Institute of Scientific and Technical Information of China (English)

    何小亮; 王晓霞

    2015-01-01

    Objective To investigate clinical effect of collagen dressing in treatment of facial hormone dependent dermatitis.Methods 107 patients were divided randomly into treatment group and control group.53 cases of control group were given citrate desloratadine,ompound glycyrrhizin tablets, 0.3% tacrolimus ointment, cod liver oil ointment for 4 weeks.54 cases of treatment group were given collagen dressing 25 minutesper night, based on control group.After 4 weeks of drug treatment,treatment group continued to be given collagen dressing once every other night, control group were given cod liver oil ointment twice a day, morning and night.Both groups continued to observe for 12 weeks, at the same time, 0.3% tacrolimus ointment was given once every other day.Compared effect of two groups in the short-term and long-term.Results There were no significant differences in symptom scores between the two groups pre-treatment; compared with pre-treatment,the symptom scores were decreased(P<0.05).Compared with control group, the symptoms of treatment group were lower than that of treatment group(P<0.05).Compared with control group, the clinical total effective rate was higher than treatment group ( P<0.05 ) .Conclusion The collagen dressing can improve the facial treatment of hormone-dependent dermatitis.%目的:观察胶原帖敷料治疗面部激素依赖性皮炎的临床疗效。方法将107例患者随机分为2组。53例对照组予枸地氯雷他定、复方甘草酸苷片、0.3%他克莫司软膏、鱼肝油软膏外用治疗4周。54例治疗组在对照组基础上每晚使用胶原帖敷料25 min。4周药物治疗后治疗组每2晚继续使用1次胶原帖敷料,对照组早晚使用鱼肝油软膏,继续观察12周,2组均继续隔天使用0.3%他克莫司软膏1次。对比2组患者短期和长期疗效。结果2组患者治疗前症状评分比较,差异无统计学意义;与治疗前比较,2组治疗后2周、4周与3月症

  8. [Blister beetle dermatitis: Dermatitis linearis].

    Science.gov (United States)

    Dieterle, R; Faulde, M; Erkens, K

    2015-05-01

    Several families of beetles cause toxic reactions on exposed human skin. Cantharidin provokes nearly asymptomatic vesicles and blisters, while pederin leads to itching and burning erythema with vesicles and small pustules, later crusts. Paederi are attracted by fluorescent light especially after rain showers and cause outbreaks in regions with moderate climate. Clinical findings and patient history lead to the diagnosis: dermatitis linearis.

  9. Dermatitis herpetiformis bodies and autoantibodies to noncutaneous organs and mitochondria in dermatitis herpetiformis

    Directory of Open Access Journals (Sweden)

    Ana Maria Abreu Velez

    2012-10-01

    Full Text Available Introduction: The precise nature of the previously described dermatitis herpetiformis bodies remains unknown.Aims: Our study was conducted to investigate the nature of dermatitis herpetiformis bodies in the skin in 7 cases of dermatitis herpetiformis, and to search for the presence of autoantibodies in other organsMethods: We utilized clinical, histopathologic, and immunologic methods to evaluate these patients.Results: Dermatitis herpetiformis bodies were found to be comprised of an amalgamation of immunoglobulins A and M, as well as molecules reactive with antibodies to armadillo repeat gene deleted in velo-cardio-facial syndrome, desmoplakins 1 and 2, and plakophilin 4. In addition, we found immunologic colocalization with selected autoantibodies associated with mitochondria in the skin, heart, kidney, and peripheral nerves. The dermatitis herpetiformis bodies did not demonstrate immunologic colocalization with tissue/epidermal transglutaminase.Conclusion: The complete biochemical nature of dermatitis herpetiformis bodies requires further characterization. Dermatitis herpetiformis bodies in these patients appear to be distinctly different than cytoid bodies. Further studies are required to determine if the antibodies to noncutaneous organs are pathogenic, and/or contribute to systemic morbility in dermatitis herpetiformis patients.

  10. Dermatitis Artefacta

    Directory of Open Access Journals (Sweden)

    Hamdan Al-Habsi

    2015-05-01

    Full Text Available Dermatitis artefacta (DA is an intentional self-inflicted dermatitis produced by patients for unconscious psychological gain. Characteristically, patients deny the responsibility for their creation. It is a poorly understood condition and, in most cases, goes on for a long period of time before a diagnosis is made. This condition creates a lot of anxiety for physicians due to a lack of awareness of the disorder and involves a considerable amount of time and resources to deal with. Suspicion usually arises when there is an unconvincing history of the evolution and recurrence of these lesions, their locations on the body, and their bizarre shapes. Here we report a typical case of DA in a 33-year-old male who repeatedly presented with oddly shaped recurrent skin lesions in the left lower leg for nine years. He had numerous doctors’ visits and tests, and was admitted to a number of different hospitals without reaching a diagnosis or a cure.

  11. Superficial Mycoses Associated with Diaper Dermatitis.

    Science.gov (United States)

    Bonifaz, Alexandro; Rojas, Rubí; Tirado-Sánchez, Andrés; Chávez-López, Dinora; Mena, Carlos; Calderón, Luz; María, Ponce-Olivera Rosa

    2016-10-01

    Diapers create particular conditions of moisture and friction, and with urine and feces come increased pH and irritating enzymes (lipases and proteases). Fungi can take advantage of all these factors. Candida yeasts, especially C. albicans, are responsible for the most frequent secondary infections and are isolated in more than 80 % of cases. Correct diagnosis is important for ensuring the correct prescription of topical antimycotics. Nystatin, imidazoles and ciclopirox are effective. It is important to realize there are resistant strains. Dermatophytes can infect the diaper area, with the most common agent being Epidermophyton floccosum. The clinical characteristics of dermatophytosis are different from those of candidiasis, and it can be diagnosed and treated simply. Malassezia yeasts can aggravate conditions affecting the diaper area, such as seborrheic dermatitis, atopic dermatitis, and inverse psoriasis. Additional treatment is recommended in this case, because they usually involve complement activation and increased specific IgE levels. Erythrasma is a pseudomycosis that is indistinguishable from candidiasis and may also occur in large skin folds. It is treated with topical antibacterial products and some antimycotics.

  12. [Rosacea, acne and other diseases of the seborrheic spectrum].

    Science.gov (United States)

    Böni, R

    2000-03-30

    Diseases of seborrhoic origin include rosacea, acne, gram-negative folliculitis, demodex-folliculorum, perioral dermatitis as well as seborrhoic dermatitis. An important prerequisite for adequate therapy is the knowledge of these different diseases. Unfortunately, topic steroids are often applied, resulting in well known corticosteroid side-effects like skin atrophy and teleangiectasias. The different clinical diseases of seborrhoic origin are reviewed here and a treatment guide is presented.

  13. Interface dermatitis

    Directory of Open Access Journals (Sweden)

    Rajiv Joshi

    2013-01-01

    Full Text Available Interface dermatitis includes diseases in which the primary pathology involves the dermo-epidermal junction. The salient histological findings include basal cell vacuolization, apoptotic keratinocytes (colloid or Civatte bodies, and obscuring of the dermo-epidermal junction by inflammatory cells. Secondary changes of the epidermis and papillary dermis along with type, distribution and density of inflammatory cells are used for the differential diagnoses of the various diseases that exhibit interface changes. Lupus erythematosus, dermatomyositis, lichen planus, graft versus host disease, erythema multiforme, fixed drug eruptions, lichen striatus, and pityriasis lichenoides are considered major interface diseases. Several other diseases (inflammatory, infective, and neoplastic may show interface changes.

  14. Effects of scalp dermatitis on chemical property of hair keratin

    Science.gov (United States)

    Kim, Kyung Sook; Shin, Min Kyung; Park, Hun-Kuk

    2013-05-01

    The effects of scalp dermatitis (seborrheic dermatitis (SD), psoriasis, and atopic dermatitis (AD)) on chemical properties of hair keratin were investigated by Fourier transform infrared (FT-IR) spectroscopy. Hairs were collected from lesional regions affected by SD, psoriasis, and AD and non-lesional regions separately. The hairs with SD were taken from patients with ages of 16-80 years. The ages of patients with psoriasis ranged from 8 to 67 years, and all patients exhibited moderate disease. Hairs with AD were taken from the patients with ages of 24-45 years and the average SCORing atopic dermatitis (SCORAD) was 48.75. Hairs from 20 normal adults were collected as a control. The FT-IR absorbance bands were analyzed by the Gaussian model to obtain the center frequency, half width, height, and area of each band. The height and area of all bands in the spectra were normalized to the amide I centered at 1652 cm-1 to quantitatively analyze the chemical composition of keratin. The spectra of hair with scalp dermatitis were different with that of control, the amide A components centered at 3278 cm-1 were smaller than those of the control. The psoriasis hair showed a large difference in the IR absorbance band between lesional and non-lesional hairs indicating good agreement with the morphological changes. The hairs with diseases did not show differences in the content of cystine, which was centered at 1054 cm-1, from the control. The chemical properties of keratin were not significantly different between the hairs affected by SD, psoriasis, and AD. However, the changes induced by scalp dermatitis were different with weathering. Therefore, FT-IR analysis could be used to screen differences between the physiological and pathological conditions of scalp hair.

  15. Clinical observation of Traditional Chinese Medicine mask combined with cold spray on facial corticosteroid dependent dermatitis%中药倒膜联合冷喷治疗面部激素依赖性皮炎疗效观察与分析

    Institute of Scientific and Technical Information of China (English)

    刘排; 李娟; 李光; 秦丽娜; 朱永军

    2015-01-01

    Objective To investigate the efficacy and safety of Traditional Chinese Medicine mask and cold spray in the treatment of facial corticosteroid dependent dermatitis. Methods Total 130 facial corticosteroid dependent dermatitis patients were randomly divided into two groups.Both of the two groups were applied Epinastine 10mg once daily and Vitamin E cream twice daily.At the same time, the treatment group were guided traditional Chinese medicine mask coordination with cold spray.The efficacy was evaluated after 8 weeks of treatment. Results The total effective rate of the treatment group was 69.23%,significantly higher than the control group(P<0.05).Patients were followed up for 2 months,they were well- tolerated and had no obvious adverse reaction and recurrence in the treatment group. Conclusion Traditional Chinese Medicine mask combined with cold spray is an effective and safe method in treatment of facial corticosteroid dependent dermatitis.%目的:评价中药倒膜联合离子喷雾仪冷喷治疗面部激素依赖性皮炎的临床疗效和安全性.方法:将入选的130例面部激素依赖性皮炎患者随机分成治疗组和对照组.所有患者均口服盐酸依匹斯汀胶囊并外用维生素E乳膏,治疗组还予外用离子喷雾仪冷喷和中药倒膜治疗,治疗8周后判定临床疗效.结果:治疗组有效率69.23%,对照组23.08%,疗效比较差异具有统计学意义(P<0.05),两组均无明显不良反应.结论:中药倒膜联合冷喷治疗面部激素依赖性皮炎疗效好,安全性高.

  16. Dermatitis, contact (image)

    Science.gov (United States)

    This picture shows a skin inflammation (dermatitis) caused by contact with a material that causes an allergic reaction in this person. Contact dermatitis is a relatively common condition, and can be caused ...

  17. Atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Watson Wade

    2011-11-01

    Full Text Available Abstract Atopic dermatitis (AD is a common, chronic skin disorder that can significantly impact the quality of life of affected individuals as well as their families. Although the pathogenesis of the disorder is not completely understood, it appears to result from the complex interplay between defects in skin barrier function, environmental and infectious agents, and immune abnormalities. There are no specific diagnostic tests for AD; therefore, the diagnosis is based on specific clinical criteria that take into account the patient’s history and clinical manifestations. Successful management of the disorder requires a multifaceted approach that involves education, optimal skin care practices, anti-inflammatory treatment with topical corticosteroids and/or topical calcineurin inhibitors (TCIs, the use of first-generation antihistamines to help manage sleep disturbances, and the treatment of skin infections. Systemic corticosteroids may also be used, but are generally reserved for the acute treatment of severe flare-ups. Topical corticosteroids are the first-line pharmacologic treatments for AD, and evidence suggests that these agents may also be beneficial for the prophylaxis of disease flare-ups. Although the prognosis for patients with AD is generally favourable, those patients with severe, widespread disease and concomitant atopic conditions, such as asthma and allergic rhinitis, are likely to experience poorer outcomes.

  18. Dermatitis artefacta?

    Science.gov (United States)

    Conde-Salazar, Luis; Valks, Ruud; Pastor, María Antonia; Gatica, María Elena; Núñez, Rodrigo; Perez Tato, Berta; Iglesias, Clara; Cuevas, Manuela

    2003-06-01

    A 35-year-old man presented with a 2-month history of intensely pruritic excoriated and crusted linear lesions on the dorsa of the left hand and left forearm (Fig 1). The patient had worked in construction for 2 years, and his job consisted mainly in covering the facades of buildings with cement. The patient was right-handed and used a black rubber glove as a protective measure only on his left hand (Fig 2). He reported that the lesions resolved partially during holidays and weekends and clearly flared in association with his work. There was no history of atopic dermatitis, drug use, or intolerance to metals, rubber, or fruits. On physical examination, linear excoriations with crusts were observed on the dorsa of the left hand, extending to the ventral and dorsal aspects of the forearm, involving the whole area that was in contact with the glove. Lichenified erythematous plaques and excoriations on the dorsal surface of the metacarpophalangeal joints and scaly lesions on the dorsal surfaces of the fingers were also present. On the palm, only discrete hyperkeratosis was seen. The right hand and forearm were free of lesions. He complained of intense pruritus when wearing the rubber glove and admitted to continuous scratching to relieve his discomfort, inducing the linear and excoriated lesions. Treatment with topical corticosteroids was initiated, with progressive resolution of the lesions.

  19. Allergic Contact Dermatitis

    OpenAIRE

    Meltem Önder

    2009-01-01

    Allergic contact dermatitis is the delayed type hypersensitivity reaction to exogenous agents. Allergic contact dermatitis may clinically present acutely after allergen exposure and initial sensitization in a previously sensitized individual. Acute phase is characterized by erythematous, scaly plaques. In severe cases vesiculation and bullae in exposed areas are very characteristic. Repeated or continuous exposure of sensitized individual with allergen result in chronic dermatitis. Lichenific...

  20. Behandlingseffekt af Digital Dermatitis

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    af klovlidelser herunder især Digital Dermatitis. Klovregistreringerne viser, at der er stor dynamik og mange nyinfektioner af Digital Dermatitis svarende til problematikken ved mastitis. Behandlingseffekten ved Digital Dermatitis er høj (omkring 90 %) ved den udførte behandling. Behandlingen bestod...

  1. Behandlingseffekt af Digital Dermatitis

    DEFF Research Database (Denmark)

    Krogh, Kenneth; Thomsen, Peter

    2008-01-01

    af klovlidelser herunder især Digital Dermatitis. Klovregistreringerne viser, at der er stor dynamik og mange nyinfektioner af Digital Dermatitis svarende til problematikken ved mastitis. Behandlingseffekten ved Digital Dermatitis er høj (omkring 90 %) ved den udførte behandling. Behandlingen bestod...

  2. Approach to atopic dermatitis in children by the Family Physician

    Directory of Open Access Journals (Sweden)

    Alysson Quitério Guilherme

    2014-05-01

    Full Text Available Atopic dermatitis (AD is a chronic and inflammatory disease that affects the skin of children in their early stages of life. Its aetiology remains little understood, but it is known that there is a dysfunction of the skin barrier, which facilitates the penetration of allergens/irritants into the epidermis, causing an inflammatory response with a predominance of Th2 response relative to Th1. The diagnosis is clinical and may be associated with previous and family medical history of atopies such as rhinitis and asthma. AD manifests itself through eczematous, pruritic injuries with the presence of erythema, papules, vesicles, and scales. The main differential diagnoses of AD are seborrheic dermatitis, contact dermatitis, psoriasis and scabies. The treatment is based on the education of patients and their families, plus the control of pruritus with antihistamines and of inflammation with corticosteroids or calcineurin inhibitors. Given the high prevalence and impact of AD on the quality of life of paediatric patients, early diagnosis and an individualized approach are paramount.

  3. Oral itraconazole for the treatment of severe seborrhoeic dermatitis

    Directory of Open Access Journals (Sweden)

    Jayasri Das

    2011-01-01

    Full Text Available Background : Seborrheic dermatitis (SD is an inflammatory skin disorder in which colonies of Malassezia furfur have been found in affected areas. Aim: The aim of this study was to evaluate the efficacy of itraconazole in the treatment of severe SD. Materials and Methods: Itraconazole was given to 30 patients of SD in a dose of 100 mg twice daily for 1 week followed by 200 mg/day for first 2 days of the following 2 months. The response was noted on day 15, 30, 60, and 90. The clinical response was graded as markedly effective, effective, or ineffective. Results: Clinical improvement (evaluated as markedly effective or effective was observed in 83.3% cases. Conclusion : The anti-inflammatory activity of oral itraconazole suggests that it should be the first-line therapy in severe SD.

  4. A Comparative Study of Two Techniques of Cryotherapy in the Treatment of Seborrheic Kreatosis

    Directory of Open Access Journals (Sweden)

    Meltem Uslu

    2008-09-01

    Full Text Available Objective: Seborrheic keratosis is a benign epidermal tumour that is generally pigmented and develop from the proliferation of epidermal keratinocytes. In this study, two different techniques, spray or probe applications used cryotherapy during the treatment of seborrheic keratosis were compared in terms of efficiency and undesired effects. By this way, it is aimed to find the most suitable technique in seborrheic keratosis treatment. Method: Eighty lesions were included in the study with the diagnosis of seborrheic keratosis. These 80 lesions were divided randomly into two groups of 40; to one of which spray cryotherapy to the second cryotherapy with probe were applied. If clinical improvement were seen treatment was accepted as successful. The patiens were evaluated 2 and 4 months after the therapy for the comparison of two treatment. The patients in both groups scored their pain from 1 to 10 during the cryotherapy.Results: In the study, great success was achieved in the treatment of seborrheic keratosis by using different cryotherapy methods. All the patients in both groups were diagnosed with hipopigmentation. They were found to continue hipopigmentation in the second and fourth months. It was found that the intensity of the pain which those in the probe cryotherapy group suffered was significantly greater statistically.Conclusion: It was concluded that spray cryotherapy should be preferred since it was less painful and required less equipment than probe cryotherapy.

  5. Contact Dermatitis in Pediatrics.

    Science.gov (United States)

    Pelletier, Janice L; Perez, Caroline; Jacob, Sharon E

    2016-08-01

    Contact dermatitis is an umbrella term that describes the skin's reaction to contacted noxious or allergenic substances. The two main categories of contact dermatitis are irritant type and allergic type. This review discusses the signs, symptoms, causes, and complications of contact dermatitis. It addresses the testing, treatment, and prevention of contact dermatitis. Proper management of contact dermatitis includes avoidance measures for susceptible children. Implementation of a nickel directive (regulating the use of nickel in jewelry and other products that come into contact with the skin) could further reduce exposure to the most common allergens in the pediatric population. [Pediatr Ann. 2016;45(8):e287-e292.].

  6. Flexural eczema versus atopic dermatitis.

    Science.gov (United States)

    Jacob, Sharon E; Goldenberg, Alina; Nedorost, Susan; Thyssen, Jacob P; Fonacier, Luz; Spiewak, Radoslaw

    2015-01-01

    Flexural eczema and atopic dermatitis are frequently synonymized. As respiratory atopy is rarely tested for and found in these patients, systematically equating a flexural distribution of dermatitis with atopic dermatitis may too frequently result in misclassified diagnoses and potentially missed opportunity for intervention toward improving patients' symptoms and quality of life. We present a critical review of the available evidence for the atopic dermatitis diagnosis and discuss the similarities between atopic dermatitis and allergic contact dermatitis. Because neither flexural predilection nor atopy is specific for atopic dermatitis, we conclude that the term atopic dermatitis is a misnomer and propose an etymologic reclassification of atopic dermatitis to "atopy-related" dermatitis. Allergic contact dermatitis can induce an atopic dermatitis-like phenotype, and thus, flexural dermatitis cannot be assumed as atopic without further testing. Patch testing should at least be considered in cases of chronic or recurrent eczema regardless of the working diagnosis.

  7. Hubungan Dermatitis Atopik dengan Kejadian Dermatitis Kontak Alergi

    OpenAIRE

    Nelly

    2015-01-01

    Background :Allergic contact dermatitis is an acquired sensitivity to various sub-stances that produce inflammatory reactions in those, and only those, who have been previously sensitized to the allergen. Atopic dermatitis is known as risk factor in the development of allergic contact dermatitis. Some studies in association between atopic dermatitis and allergic contact dermatitis incidence have found variety results. Objective :To investigate the association between atopic dermatitis and ...

  8. Flexural eczema versus atopic dermatitis

    DEFF Research Database (Denmark)

    Jacob, Sharon E; Goldenberg, Alina; Nedorost, Susan

    2015-01-01

    Flexural eczema and atopic dermatitis are frequently synonymized. As respiratory atopy is rarely tested for and found in these patients, systematically equating a flexural distribution of dermatitis with atopic dermatitis may too frequently result in misclassified diagnoses and potentially missed...

  9. Epidemiological Study of Periocular Dermatitis in a Specialised Hospital Department

    Directory of Open Access Journals (Sweden)

    Rafael Rojo-España

    2011-09-01

    Full Text Available Contact dermatitis is frequent skin pathology and eyelids are one of the more frequent locations of this pathology. The objective of the present work was to study the population distribution of periocular dermatitis, determine the allergens which most frequently indicate positive in patch tests and in provocative use tests, and analyse the clinical relevance of the positive tests.Patients with periocular dermatitis (N=93 underwent a thorough physical examination and a patch test with standard series. According to clinical suspicions, 76 patients underwent a patch test with specific series. Finally a provocative use test was done for 36 patients with suspected  products  that  the  patients  brought.  The  tests  were classified according their relevance.The most  frequently observed allergen in the  patch tests (with standard and specific series was nickel followed by mercury, and anti-glaucoma drops in the provocative use tests with patients products.Patients’ sex, age, occupation, clinical status, presence of associated periocular symptoms, and presence of atopic or seborrheic dermatitis and/or rosacea did not relate with relevance.We conclude that  a clinical diagnosis may not  always be made with patch tests with standard and specific series due to lack of relevance. It is important to do provocative use tests with the products suspected as allergens in those cases where patch tests with standard and specific series indicated positive for more than one allergen.

  10. Allergic Contact Dermatitis

    Directory of Open Access Journals (Sweden)

    Meltem Önder

    2009-03-01

    Full Text Available Allergic contact dermatitis is the delayed type hypersensitivity reaction to exogenous agents. Allergic contact dermatitis may clinically present acutely after allergen exposure and initial sensitization in a previously sensitized individual. Acute phase is characterized by erythematous, scaly plaques. In severe cases vesiculation and bullae in exposed areas are very characteristic. Repeated or continuous exposure of sensitized individual with allergen result in chronic dermatitis. Lichenification, erythematous plaques, hyperkeratosis and fissuring may develop in chronic patients. Allergic contact dermatitis is very common dermatologic problem in dermatology daily practice. A diagnosis of contact dermatitis requires the careful consideration of patient history, physical examination and patch testing. The knowledge of the clinical features of the skin reactions to various contactans is important to make a correct diagnosis of contact dermatitis. It can be seen in every age, in children textile product, accessories and touch products are common allergens, while in adults allergic contact dermatitis may be related with topical medicaments. The contact pattern of contact dermatitis depends on fashion and local traditions as well. The localization of allergic reaction should be evaluated and patients’ occupation and hobbies should be asked. The purpose of this review is to introduce to our collaques up dated allergic contact dermatitis literatures both in Turkey and in the World.

  11. Facial paralysis

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003028.htm Facial paralysis To use the sharing features on this page, please enable JavaScript. Facial paralysis occurs when a person is no longer able ...

  12. Clinical Research on Mechanism of "Jia-Jian Xiao-Yao Powder" Improving Facial Skin Barrier Function of Hormone-dependent Dermatitis Patients%加减逍遥散改善面部激素依赖性皮炎患者皮肤屏障功能的临床研究*

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    This study was aimed to observe the mechanism of "Jia-Jian Xiao-Yao (JJXY) Powder" improving facial skin barrier function of the hormone-dependent dermatitis patients. A total of 100 patients were randomly divided into two groups. In the treatment group, 50 cases were orally administered with JJXY Powder. In the control group, loratadine and vitamin EC particles were orally administered to the 50 cases. Thirty days is one treatment course. Changes of transepidermal water loss (TEWL), skin erythema amount and IL-4 were detected in patients of both groups before and after the treatment. The results showed that the clinical efficiency of treatment group and control group was 82.0% and 58.0%, respectively. In the treatment group, the TEWL and skin erythema amount were obviously decreased after the treatment (P < 0.05). In the treatment group, the decreasing range of serum IL-4 was significant compared to control group (P < 0.05). It was concluded that JJXY Powder is one of the effective methods for the treatment of facial hormone-dependent dermatitis. It is able to repair facial hormone-dependent dermatitis in patients with impaired skin barrier function and reduce the amount of skin erythema. The therapeutic mechanism may be related to the regulation of serum IL-4.%  目的:观察加减逍遥散治疗面部糖皮质激素依赖性皮炎的临床疗效,探讨其改善面部皮肤屏障功能的作用机制。方法:将100例患者随机分为两组,50例治疗组内服加减逍遥散;50例对照组内服氯雷他定、维生素 EC 颗粒。30天为1个疗程。测定两组患者治疗前后经皮水分丢失量(TEWL)和皮肤红斑量,并同时检测血清IL-4变化情况。结果:治疗组与对照组临床有效率分别是82.0%、58.0%。治疗组治疗后TEWL、皮肤红斑量均显著降低(P约0.05)。治疗组血清IL-4水平降低幅度明显大于对照组(P约0.05)。结论:加减逍遥散可修复面部激素依赖性皮炎

  13. Facial asymmetry: a case report of localized linear scleroderma patient with muscular strain and spasm

    OpenAIRE

    Kim, Jae-Hyung; Lee, Suck-Chul; Kim, Chul-Hoon; Kim, Bok-Joo

    2015-01-01

    Facial asymmetry is found in patients with or without cosmetic facial alterations. Some patients have facial asymmetry that manifests underlying skeletal problems, while others have only limited soft-tissue facial asymmetry. Orthognathic surgery brings about a dermatic change, as soft tissue covers underlying bones. Limited soft-tissue asymmetry, meanwhile, is difficult to correct. The treatment modalities for the creation or restoration of an esthetically pleasing appearance were autogenous ...

  14. 面部糖皮质激素依赖性皮炎中西医综合疗法进展%Research Progress on integrated Chinese and western medicine therapy on facial corticosteroid deperdent dermatitis

    Institute of Scientific and Technical Information of China (English)

    蒋玲钰

    2015-01-01

    面部激素依赖性皮炎(hormone dependence dermatitis,HDD),它是由面部长期使用激素制剂而造成的一种常见病,其表现为皮肤潮红脱屑并伴灼热、瘙痒的皮肤病,该病发病率日益增多,病程反复难愈,目前对该病的治疗以中西医并重、内外治相结合为最佳.

  15. Contact dermatitis. A review

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner; Benezra, C; Burrows, D;

    1987-01-01

    In recent years, there has been a dramatic rise in our understanding of contact dermatitis. This paper is a review of our knowledge of the mechanisms involved in contact dermatitis and related phenomena, the investigation of these events and the emergence of significant new allergens during...

  16. Paederus dermatitis featuring chronic contact dermatitis.

    Science.gov (United States)

    Stanimirović, Andrija; Skerlev, Mihael; Culav-Košćak, Ivana; Kovačević, Maja

    2013-01-01

    Paederus dermatitis is a distinct variant of acute irritant contact dermatitis caused by mucocutaneous contact with the specific toxin of an insect belonging to the genus Paederus. It is characterized by the sudden onset of erythema and vesiculobullous lesions on exposed skin, with special predilection for the periorbital region. Paederus species have been mostly identified in Africa, Asia, Australia, and Central/South America. We report a 51-year-old woman who experienced 4 recurrences of periorbital erythema and edema in the previous year. No consistent etiology could be established at the beginning. Only after taking a detailed medical history was it discovered that 1 year before our examination, the patient had traveled to Kenya, where she had experienced contact with the insect. This fact led us to the diagnosis of Paederus dermatitis. After appropriate treatment, a complete regression was observed over a 3-week period.

  17. [Facial palsy].

    Science.gov (United States)

    Cavoy, R

    2013-09-01

    Facial palsy is a daily challenge for the clinicians. Determining whether facial nerve palsy is peripheral or central is a key step in the diagnosis. Central nervous lesions can give facial palsy which may be easily differentiated from peripheral palsy. The next question is the peripheral facial paralysis idiopathic or symptomatic. A good knowledge of anatomy of facial nerve is helpful. A structure approach is given to identify additional features that distinguish symptomatic facial palsy from idiopathic one. The main cause of peripheral facial palsies is idiopathic one, or Bell's palsy, which remains a diagnosis of exclusion. The most common cause of symptomatic peripheral facial palsy is Ramsay-Hunt syndrome. Early identification of symptomatic facial palsy is important because of often worst outcome and different management. The prognosis of Bell's palsy is on the whole favorable and is improved with a prompt tapering course of prednisone. In Ramsay-Hunt syndrome, an antiviral therapy is added along with prednisone. We also discussed of current treatment recommendations. We will review short and long term complications of peripheral facial palsy.

  18. Contact dermatitis in Alstroemeria workers.

    Science.gov (United States)

    van der Mei, I A; de Boer, E M; Bruynzeel, D P

    1998-09-01

    Hand dermatitis is common in workers in the horticultural industry. This study determined the prevalence of hand dermatitis in workers of Alstroemeria cultivation, investigated how many workers had been sensitized by tulipalin A (the allergen in Alstroemeria) and took stock of a wide range of determinants of hand dermatitis. The 12-month period prevalence of major hand dermatitis amounted to 29.5% whereas 7.4% had minor dermatitis. Of these workers, 52.1% were sensitized for tulipalin A. Several personal and work-related determinants played a role in the multifactorial aetiology of hand dermatitis. Factors which showed a significant relationship with major hand dermatitis were: female sex, atopic dermatitis, chapped hands and the frequency of washing hands. It may be concluded that the Alstroemeria workers are a population at risk of developing contact dermatitis and it might be useful to carry out an educational campaign to lower the high prevalence.

  19. Acrylate Systemic Contact Dermatitis.

    Science.gov (United States)

    Sauder, Maxwell B; Pratt, Melanie D

    2015-01-01

    Acrylates, the 2012 American Contact Dermatitis Society allergen of the year, are found in a range of products including the absorbent materials within feminine hygiene pads. When fully polymerized, acrylates are nonimmunogenic; however, if not completely cured, the monomers can be potent allergens.A 28-year-old woman is presented, who had her teeth varnished with Isodan (Septodont, Saint-Maur-des-Fossés, France) containing HEMA (2-hydroxyethyl methacrylate) with no initial reaction. Approximately 1 month later, the patient developed a genital dermatitis secondary to her feminine hygiene pads. The initial reaction resolved, but 5 months later, the patient developed a systemic contact dermatitis after receiving a second varnishing.The patient was dramatically patch test positive to many acrylates. This case demonstrates a reaction to likely unpolymerized acrylates within a feminine hygiene pad, as well as broad cross-reactivity or cosensitivity to acrylates, and possibly a systemic contact dermatitis with systemic re-exposure to unpolymerized acrylates.

  20. Shoe allergic contact dermatitis.

    Science.gov (United States)

    Matthys, Erin; Zahir, Amir; Ehrlich, Alison

    2014-01-01

    Foot dermatitis is a widespread condition, affecting men and women of all ages. Because of the location, this condition may present as a debilitating problem to those who have it. Allergic contact dermatitis involving the feet is frequently due to shoes or socks. The allergens that cause shoe dermatitis can be found in any constituent of footwear, including rubber, adhesives, leather, dyes, metals, and medicaments. The goal of treatment is to identify and minimize contact with the offending allergen(s). The lack of product information released from shoe manufacturers and the continually changing trends in footwear present a challenge in treating this condition. The aim of this study is to review the current literature on allergic contact shoe dermatitis; clinical presentation, allergens, patch testing, and management will be discussed. PubMed and MEDLINE databases were used for the search, with a focus on literature updates from the last 15 years.

  1. Poison Ivy Dermatitis

    Science.gov (United States)

    ... Favorite Name: Category: Share: Yes No, Keep Private Poison Ivy Dermatitis Share | "Leaves of three - let it ... has a longer stem than the other two. Poison ivy clings to tree trunks and other vertical ...

  2. Airborne contact dermatitis and asthma in a nail art operator

    Directory of Open Access Journals (Sweden)

    Mario Vaccaro

    2014-02-01

    Full Text Available Nail art (creation and decoration of artificial nails is a growing fashion trend. Proportionally to its popularity, the number of allergic reactions to the materials used has recently increased. We report the case of a nail art operator who developed occupational allergy to acrylates, manifested with the unusual simultaneous presence of asthma and dermatitis. Cutaneous lesions only affected areas not covered by individual protection devices or clothes, even if such areas were not in direct contact with acrylates, suggesting airborne allergic contact dermatitis. While respiratory problems were solved with the correct use of a mask at the workplace, facial dermatitis proved impossible to avoid or control and, for this reason, the patient had to change her work.

  3. Oral Steroids for Dermatitis.

    Science.gov (United States)

    Fisher, Andrew D; Clarke, Jesse; Williams, Timothy K

    2015-01-01

    Contact/allergic dermatitis is frequently treated inappropriately with lower-than-recommended doses or inadequate duration of treatment with oral and intramuscular glucocorticoids. This article highlights a case of dermatitis in a Ranger Assessment and Selection Program student who was improperly treated over 2 weeks with oral steroids after being bit by Cimex lectularius, commonly known as bed bugs. The article also highlights the pitfalls of improper oral steroid dosing and provides reasoning for longer-duration oral steroid treatment.

  4. Stinging nettle dermatitis.

    Science.gov (United States)

    Anderson, Bryan E; Miller, Christopher J; Adams, David R

    2003-03-01

    The stinging nettle (Urtica dioica) is a common weed that can cause a wide range of cutaneous reactions. Contact with the hairs or spines on the stems and leaves of the stinging nettle causes the release of several biologically active substances. The released chemicals act to cause itching, dermatitis, and urticaria within moments of contact. Extracts from the stinging nettle may provide therapeutic value for some inflammatory medical conditions. There is no standard treatment for stinging nettle dermatitis.

  5. Purpuric agave dermatitis.

    Science.gov (United States)

    Ricks, M R; Vogel, P S; Elston, D M; Hivnor, C

    1999-02-01

    Agave americana is a low growing, thick, long-leaved, subtropical plant used for medicinal, commercial, and ornamental purposes. The plant's sap contains calcium oxalate crystals, acrid oils, saponins, and other compounds. Despite these known irritants, Agave-induced irritant dermatitis has rarely been reported. Previous case reports have noted a papulovesicular eruption consistent with an irritant contact dermatitis. We report a case of Agave-induced purpura in an otherwise healthy patient. Histopathology was consistent with an evolving leukocytoclastic vasculitis.

  6. Facial swelling

    Science.gov (United States)

    ... help reduce facial swelling. When to Contact a Medical Professional Call your health care provider if you have: Sudden, painful, or severe facial ... or if you have breathing problems. The health care provider will ask about your medical and personal history. This helps determine treatment or ...

  7. Allergic contact dermatitis in children.

    Science.gov (United States)

    Fontana, E; Belloni Fortina, A

    2014-12-01

    Allergic contact dermatitis is an inflammatory skin disease (delayed type hypersensitivity reaction) that accounts for up to 20% of all childhood dermatitis. Allergic contact dermatitis represents a clinical manifestation of contact sensitization and usually occurs at skin sites that have come into contact with the allergen. The clinical features of allergic contact dermatitis are itchy eczematous lesions. Prevalence of contact sensitization varies between 27% and 96% of children with suspected contact dermatitis. The relationship between contact sensitization and atopic dermatitis has been widely discussed but only conflicting data have been reported. Epicutaneous patch testing is the gold standard for the diagnosis of allergic contact dermatitis. The most common allergens detected in children are: metals, topical medicaments, fragrances, and preservatives. The first line management of allergic contact dermatitis in children is to avoid the offending allergens identified with the patch test and a topical corticosteroid therapy.

  8. Protein Linked to Atopic Dermatitis

    Science.gov (United States)

    ... Research Matters NIH Research Matters January 14, 2013 Protein Linked to Atopic Dermatitis Normal skin from a ... in mice suggests that lack of a certain protein may trigger atopic dermatitis, the most common type ...

  9. Atopic Dermatitis - A Clinical Profile

    Directory of Open Access Journals (Sweden)

    Kumar Pramod

    1998-01-01

    Full Text Available A total of 80 atopic dermatitis cases were studied. The incidence was 4.2 per 1000 among OPD patients. The overall crude M : F ratio was 1.4:1 which after standardization was 0.9:1, 32.5% had the disease for the first time, 48.75% of patients had observed itching preceding rash, 26% of patients gave history of food allergy. The incidence of personal history of atopy and family history of atopy was 56.25% and 63.75% respectively. Facial involvement was common in infant and flexural involvement in adolescent and adult. Vesiculation, papules, erythema were common in all. Lichenification was seen in chronic cases, 18% of the patients had ichtyosis vulgaris and 93% of infantile, 55% of childhood and 57% of adult cases had xerotic skin. Hyperlinear palms were seen in 38% and keratosis pilaris in 34%. Dennie-Morgan line was seen in 50% of the cases. White dermographism was demonstrated in 50% of 66 cases tested. Secondary cutaneous infections were common.

  10. Management of Atopic Hand Dermatitis

    DEFF Research Database (Denmark)

    Halling-Overgaard, Anne-Sofie; Zachariae, Claus; Thyssen, Jacob P

    2017-01-01

    This article provides an overview of clinical aspects of hand eczema in patients with atopic dermatitis. Hand eczema can be a part of atopic dermatitis itself or a comorbidity, for example, as irritant or allergic contact dermatitis. When managing hand eczema, it is important to first categorize...

  11. Tomato contact dermatitis

    DEFF Research Database (Denmark)

    Paulsen, Evy; Christensen, Lars P; Andersen, Klaus Ejner

    2012-01-01

    The tomato plant (Solanum lycopersicum) is an important crop worldwide. Whereas immediate-type reactions to tomato fruits are well known, contact dermatitis caused by tomatoes or tomato plants is rarely reported. The aims of this study were to present new data on contact sensitization to tomato...... plants and review the literature on contact dermatitis caused by both plants and fruits. An ether extract of tomato plants made as the original oleoresin plant extracts, was used in aimed patch testing, and between 2005 and 2011. 8 of 93 patients (9%) tested positive to the oleoresin extracts....... This prevalence is in accordance with the older literature that reports tomato plants as occasional sensitizers. The same applies to tomato fruits, which, in addition, may cause protein contact dermatitis. The allergens of the plant are unknown, but both heat-stable and heat-labile constituents seem...

  12. ALLERGIC CONTACT DERMATITIS

    Directory of Open Access Journals (Sweden)

    Trisna Yuliharti Tersinanda

    2013-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Allergic contact dermatitis is an immunologic reaction that tends to involve the surrounding skin and may even spread beyond affected sites. This skin disease is one of the more frequent, and costly dermatologic problems. Recent data from United Kingdom and United States suggest that the percentage of occupational contact dermatitis due to allergy may be much higher, thus raising the economic impact of occupational allergic contact dermatitis. There is not enough data about the epidemiology of allergic contact dermatitis in Indonesia, however based on research that include beautician in Denpasar, about 27,6 percent had side effect of cosmetics, which is 25,4 percent of it manifested as allergic contact dermatitis. Diagnosis of allergic contact dermatitis is based on anamnesis, physical examination, patch test, and this disease should be distinguished from other eczematous skin disease. The management is prevention of allergen exposure, symptomatic treatment, and physicochemical barrier /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  13. Allergic contact dermatitis.

    Science.gov (United States)

    Gober, Michael D; Gaspari, Anthony A

    2008-01-01

    Allergic contact dermatitis is a classic example of a cell mediated hypersensitivity reaction in the skin. This occurs as a result of xenobiotic chemicals penetrating into the skin, chemically reacting with self proteins, eventually resulting in a hapten-specific immune response. It is precisely because of this localized immune response that allergic signs and symptoms occur (redness, edema, warmth and pruritus). It has been known for years that conventional T-cells (CD4+ or CD8+ T-cells that express a T-cell receptor alpha/Beta) are critical effectors for this reaction. There is emerging evidence that innate immune lymphocytes such as invariant Natural killer T-cells and even Natural killer cells may play important role. Other T-cell types such as Tregulatory cells and the IL-10 secreting Tregulatory cells type I are likely to be important in the control (resolution) of allergic contact dermatitis. Other cell types that may contribute include B-cells and hapten-specific IgM. Additionally, epidermal Langerhans cells have been ascribed an indispensable role as an antigen presenting cell to educate T-cells of the skin immune system. Studies of mice that lack this cell type suggest that Langerhans cells may be dispensible, and may even play a regulatory role in allergic contact dermatitis. The identity of the antigen presenting cells that complement Langerhans cells has yet to be identified. Lastly, Keratinocytes play a role in all phases of allergic contact dermatitis, from the early initiation phase with the elaboration of inflammatory cytokines, that plays a role in Langerhans cell migration, and T-cell trafficking, through the height of the inflammatory phase with direct interactions with epidermotrophic T-cells, through the resolution phase of allergic contact dermatitis with the production of anti-inflammatory cytokines and tolerogenic antigen presentation to effector T-cells. As the understanding of allergic contact dermatitis continues to improve, this will

  14. Facial anatomy.

    Science.gov (United States)

    Marur, Tania; Tuna, Yakup; Demirci, Selman

    2014-01-01

    Dermatologic problems of the face affect both function and aesthetics, which are based on complex anatomical features. Treating dermatologic problems while preserving the aesthetics and functions of the face requires knowledge of normal anatomy. When performing successfully invasive procedures of the face, it is essential to understand its underlying topographic anatomy. This chapter presents the anatomy of the facial musculature and neurovascular structures in a systematic way with some clinically important aspects. We describe the attachments of the mimetic and masticatory muscles and emphasize their functions and nerve supply. We highlight clinically relevant facial topographic anatomy by explaining the course and location of the sensory and motor nerves of the face and facial vasculature with their relations. Additionally, this chapter reviews the recent nomenclature of the branching pattern of the facial artery.

  15. Facial tics

    Science.gov (United States)

    Tic - facial; Mimic spasm ... Tics may involve repeated, uncontrolled spasm-like muscle movements, such as: Eye blinking Grimacing Mouth twitching Nose wrinkling Squinting Repeated throat clearing or grunting may also be ...

  16. Facial Recognition

    National Research Council Canada - National Science Library

    Mihalache Sergiu; Stoica Mihaela-Zoica

    2014-01-01

    .... From birth, faces are important in the individual's social interaction. Face perceptions are very complex as the recognition of facial expressions involves extensive and diverse areas in the brain...

  17. Contact dermatitis in Nigeria.

    Science.gov (United States)

    Olumide, Y M

    1985-05-01

    Nickel is the most important sensitizer in Lagos, with an incidence of 12.3% of 453 patients tested. There was no sex difference, as the wearing of necklaces and bracelets was equally fashionable among both sexes. Housewife eczema is not common, probably because of hardening. Dermatitis from additives in the processing of leather and rubber footwear was the next most common. Chromate sensitivity comes usually from leather or cement. Cultural and climatic factors are mainly responsible for differences in the incidence of contact dermatitis found in Lagos from other countries.

  18. Colors and contact dermatitis.

    Science.gov (United States)

    Bonamonte, Domenico; Foti, Caterina; Romita, Paolo; Vestita, Michelangelo; Angelini, Gianni

    2014-01-01

    The diagnosis of skin diseases relies on several clinical signs, among which color is of paramount importance. In this review, we consider certain clinical presentations of both eczematous and noneczematous contact dermatitis in which color plays a peculiar role orientating toward the right diagnosis. The conditions that will be discussed include specific clinical-morphologic subtypes of eczematous contact dermatitis, primary melanocytic, and nonmelanocytic contact hyperchromia, black dermographism, contact chemical leukoderma, and others. Based on the physical, chemical, and biologic factors underlying a healthy skin color, the various skin shades drawing a disease picture are thoroughly debated, stressing their etiopathogenic origins and histopathologic aspects.

  19. Granulomatøs perioral dermatitis i barnealderen hos et adoptivbarn fra Madagaskar

    DEFF Research Database (Denmark)

    Mørtz, Charlotte Gotthard; Deleuran, Mette Søndergaard

    2008-01-01

    A case of childhood granulomatous perioral dermatitis (CGPD)/facial Afro-Caribbean childhood eruption (FACE) in a three year old boy from Madagascar is described. This disorder occurs predominantly in black children until puberty. It is a relatively uncommon condition of unknown aetiology...

  20. Irritant contact dermatitis.

    Science.gov (United States)

    Ale, Iris S; Maibach, Howard I

    2014-01-01

    Irritant contact dermatitis (ICD) is the most common form of contact dermatitis. It represents the cutaneous response to the toxic/physical effects of a wide variety of environmental agents. Nowadays, it is recognized that irritancy does not represent a single monomorphous entity but rather a complex biologic syndrome with diverse pathophysiology and clinical manifestations. The clinical presentation is highly variable depending on several factors, including properties and strength of the irritant, dose, duration and frequency of exposure, environmental factors, and skin susceptibility. The pathophysiological mechanism depends on activation of the innate immune system and involves skin barrier disruption, cellular changes, and release of proinflammatory mediators that directly recruit and activate T lymphocytes. The diagnosis of irritant contact dermatitis is often clinical, and involves a comprehensive history and examination, as well as the exclusion of allergic contact dermatitis with patch testing. Recent advances in understanding the pathogenesis as well as better awareness of the clinical significance of ICD will lead to a improved care for our patients.

  1. Coral contact dermatitis

    OpenAIRE

    Jefferson, Julie; Thompson, Curtis; Hinshaw, Molly; Rich, Phoebe

    2015-01-01

    Corals can elicit both toxic and allergic reactions upon contact with the skin. Clinical presentations vary depending on whether the reaction is acute, delayed, or chronic. Literature concerning cutaneous reactions to corals and other Cnidarians is scarce. Herein we report a case of delayed contact hypersensitivity reaction to coral and review the clinical and histopathological features of coral contact dermatitis.

  2. Coral contact dermatitis.

    Science.gov (United States)

    Jefferson, Julie; Thompson, Curtis; Hinshaw, Molly; Rich, Phoebe

    2015-04-16

    Corals can elicit both toxic and allergic reactions upon contact with the skin. Clinical presentations vary depending on whether the reaction is acute, delayed, or chronic. Literature concerning cutaneous reactions to corals and other Cnidarians is scarce. Herein we report a case of delayed contact hypersensitivity reaction to coral and review the clinical and histopathological features of coral contact dermatitis.

  3. Allergic contact dermatitis.

    Science.gov (United States)

    Becker, Detlef

    2013-07-01

    Allergic contact dermatitis is a frequent inflammatory skin disease. The suspected diagnosis is based on clinical symptoms, a plausible contact to allergens and a suitable history of dermatitis. Differential diagnoses should be considered only after careful exclusion of any causal contact sensitization. Hence, careful diagnosis by patch testing is of great importance. Modifications of the standardized test procedure are the strip patch test and the repeated open application test. The interpretation of the SLS (sodium lauryl sulfate) patch test as well as testing with the patients' own products and working materials are potential sources of error. Accurate patch test reading is affected in particular by the experience and individual factors of the examiner. Therefore, a high degree of standardization and continuous quality control is necessary and may be supported by use of an online patch test reading course made available by the German Contact Dermatitis Research Group. A critical relevance assessment of allergic patch test reactions helps to avoid relapses and the consideration of differential diagnoses. Any allergic test reaction should be documented in an allergy ID card including the INCI name, if appropriate. The diagnostics of allergic contact dermatitis is endangered by a seriously reduced financing of patch testing by the German statutory health insurances. Restrictive regulations by the German Drug Law block the approval of new contact allergens for routine patch testing. Beside the consistent avoidance of allergen contact, temporary use of systemic and topical corticosteroids is the therapy of first choice.

  4. Fabrics for atopic dermatitis.

    Science.gov (United States)

    Mason, Rupert

    2008-01-01

    The type of fabric worn by sufferers from atopic dermatitis should not exacerbate the condition but, if possible, help to control it. Synthetic fabrics and wool tend to produce itching and irritate the skin. Cotton is traditionally recommended but its structure contains short fibres which expand and contract, causing a rubbing movement that can irritate delicate skin. Dyes used in cotton garments can increase the potential of a sensitivity reaction. Cotton is also prone to bacterial and fungal attack. Silk garments are often closely woven which impedes the flow of air, and some people are allergic to the sericin protein in silk. Published studies suggest that a specially treated silk material (DermaSilk), which is loosely knitted, has had the sericin removed and has a microbial agent (AEM 5772/5) permanently bonded to it, is well tolerated and has beneficial effects on the skin of children and adults with atopic dermatitis. Atopic dermatitis often becomes infected, commonly with Staphylococcus aureus. Some studies have investigated the use of clothing materials impregnated with substances such as silver, which has antimicrobial properties. However, these are still unproven and there are concerns about bacterial resistance and the local and environmental effects of silver. The use of the antimicrobial AEM 5772/5, which does not transfer to the skin of the patient, is a new development in the control of atopic dermatitis. Further studies are needed to determine whether an antimicrobial shield bonded to clothing material will reduce the colonisation of atopic skin by S. aureus.

  5. Facial Sports Injuries

    Science.gov (United States)

    ... Find an ENT Doctor Near You Facial Sports Injuries Facial Sports Injuries Patient Health Information News media interested in ... should receive immediate medical attention. Prevention Of Facial Sports Injuries The best way to treat facial sports injuries ...

  6. Children and Facial Trauma

    Science.gov (United States)

    ... an ENT Doctor Near You Children and Facial Trauma Children and Facial Trauma Patient Health Information News ... staff at newsroom@entnet.org . What is facial trauma? The term facial trauma means any injury to ...

  7. Facial Cosmetic Surgery

    Science.gov (United States)

    ... to find out more. Facial Cosmetic Surgery Facial Cosmetic Surgery Extensive education and training in surgical procedures ... to find out more. Facial Cosmetic Surgery Facial Cosmetic Surgery Extensive education and training in surgical procedures ...

  8. Facial Scar Revision: Understanding Facial Scar Treatment

    Science.gov (United States)

    ... a facial plastic surgeon Facial Scar Revision Understanding Facial Scar Treatment When the skin is injured from a cut or tear the body heals by forming scar tissue. The appearance of the scar can range from ...

  9. Facial blindsight

    Directory of Open Access Journals (Sweden)

    Marco eSolcà

    2015-09-01

    Full Text Available Blindsight denotes unconscious residual visual capacities in the context of an inability to consciously recollect or identify visual information. It has been described for color and shape discrimination, movement or facial emotion recognition. The present study investigates a patient suffering from cortical blindness whilst maintaining select residual abilities in face detection. Our patient presented the capacity to distinguish between jumbled/normal faces, known/unknown faces or famous people’s categories although he failed to explicitly recognize or describe them. Conversely, performance was at chance level when asked to categorize non-facial stimuli. Our results provide clinical evidence for the notion that some aspects of facial processing can occur without perceptual awareness, possibly using direct tracts from the thalamus to associative visual cortex, bypassing the primary visual cortex.

  10. Seborrheic inclusion cyst of the skin positive for cytoplasmic inclusion bodies and HPV antigen.

    Science.gov (United States)

    Terada, Tadashi

    2012-01-01

    Seborrheic inclusion cyst (SIC) is a very rare variant of epidermal cyst of the skin. SIC shows seborrheic keratosis (SK)-like lesion in epidermal cyst. SIC is extremely rare; only 6 case reports have been published in the English literature. However, no immunohistochemical study of SIC has been reported. A 41-year-old Japanese man noticed a subcutaneous tumor in the neck. Physical examination showed slightly mobile tumor in the subcutaneous tissue, and total excision was performed. Grossly, the tumor (1 x 1 x 0.8 cm) was cyst containing atheromatous keratin. Microscopically, the lesion is a cyst containing keratins. About one half of the cyst showed features of epidermal cyst consisting of mature squamous epithelium with granular layers. The other one half showed SK-like epidermal proliferation. The SK-like area showed basaloid cell proliferation with pseudohorn cysts. No significant atypia was noted. Many eosinophilic cytoplasmic inclusion bodies were noted in the SK-like area. Immunohistochemically, the SK-like area was positive for pancytokeratin AE1/3, pancytokeratin CAM5.2, p63, and Ki-67 (labeling=8%) and HPV, but negative for p53. The pathological diagnosis was SIC.

  11. Rejuvenecimiento facial

    Directory of Open Access Journals (Sweden)

    L. Daniel Jacubovsky, Dr.

    2010-01-01

    Full Text Available El envejecimiento facial es un proceso único y particular a cada individuo y está regido en especial por su carga genética. El lifting facial es una compleja técnica desarrollada en nuestra especialidad desde principios de siglo, para revertir los principales signos de este proceso. Los factores secundarios que gravitan en el envejecimiento facial son múltiples y por ello las ritidectomías o lifting cérvico faciales descritas han buscado corregir los cambios fisonómicos del envejecimiento excursionando, como se describe, en todos los planos tisulares involucrados. Esta cirugía por lo tanto, exige conocimiento cabal de la anatomía quirúrgica, pericia y experiencia para reducir las complicaciones, estigmas quirúrgicos y revisiones secundarias. La ridectomía facial ha evolucionado hacia un procedimiento más simple, de incisiones más cortas y disecciones menos extensas. Las suspensiones musculares han variado en su ejecución y los vectores de montaje y resección cutánea son cruciales en los resultados estéticos de la cirugía cérvico facial. Hoy estos vectores son de tracción más vertical. La corrección de la flaccidez va acompañada de un interés en reponer el volumen de la superficie del rostro, en especial el tercio medio. Las técnicas quirúrgicas de rejuvenecimiento, en especial el lifting facial, exigen una planificación para cada paciente. Las técnicas adjuntas al lifting, como blefaroplastias, mentoplastía, lipoaspiración de cuello, implantes faciales y otras, también han tenido una positiva evolución hacia la reducción de riesgos y mejor éxito estético.

  12. Ultraviolet Type B-Radiation-Induced Hyperplasia and Seborrheic Keratosis is Reduced by Application of Commercial Sunscreens

    Directory of Open Access Journals (Sweden)

    Azad K Saeed1*, Snur MA Hassan1 and Nali A Maaruf2

    2016-11-01

    Full Text Available Fifty-six mice were classified into four groups; Group A (control group, n=8, Group B (exposure group, n=16, Group C (n=16 treated with sunscreen 15 minutes before UVB irradiations and group D (n=16 sunscreen treated 60 minutes before UVB exposure. Mice were irradiated 30 minutes 5days/week (12 weeks, and group C-D treated five days/week (12 weeks. Skin samples were taken in the mid and end of the experiment. The result of this study revealed that, epidermal thickness in group A was 7.155µm. At the mid-period of the experiment, severe epidermal hyperplasia was observed in group B with epidermal thickness 118.712µm, while in group C and D mild to moderate epidermal hyperplasia were noted with decreasing epidermal thickness to 64.154 and 90.042µm respectively. At the end of the experiment in Group B epidermal thickness reached to 281.35µm with seborrheic keratosis development, whereas in group C and D totally inhibited the development of seborrheic keratosis and epidermal thickness decreased again into 42.347 and 55.915µm. In conclusion, chronic UVB radiation-led to epidermal hyperplasia and seborrheic keratosis, sunscreen prevented the development of seborrheic keratosis and decreased the UVB-induced epidermal hyperplasia.

  13. DERMATITIS KONTAK AKIBAT KERJA PADA PEKERJA GARMEN

    OpenAIRE

    I Made Stepanus Biondi Pramantara; I Made Brathiarta

    2014-01-01

    Occupational contact dermatitis is a dermatitis that occurs due to contact with thematerials that exist in the workplace, and this is not the case if the person does not work.In the textile workers, the incidence of occupational contact dermatitis ranks fourth ofall occupational skin diseases annually in Finland. Contact dermatitis is of two kinds,namely contact dermatitis (DKI) arising through non-immunologic mechanisms andallergic contact dermatitis (DKA)as a result of specific immunologic ...

  14. [Contact dermatitis from Agave americana].

    Science.gov (United States)

    de la Cueva, Pablo; González-Carrascosa, Mateo; Campos, Minia; Leis, Vicente; Suárez, Ricardo; Lázaro, Pablo

    2005-10-01

    Numerous plant species and their derivatives can cause skin reactions through a variety of mechanisms: irritative contact dermatitis, allergic contact dermatitis, contact urticaria and photodermatitis. We present a case of irritative contact dermatitis after exposure to the sap of Agave americana. The skin symptoms in this case have only been described on rare occasions; although this condition usually presents with a papulovesicular rash, in this patient it appeared as purpuric lesions in the contact area.

  15. Fragrance allergic contact dermatitis.

    Science.gov (United States)

    Cheng, Judy; Zug, Kathryn A

    2014-01-01

    Fragrances are a common cause of allergic contact dermatitis in Europe and in North America. They can affect individuals at any age and elicit a spectrum of reactions from contact urticaria to systemic contact dermatitis. Growing recognition of the widespread use of fragrances in modern society has fueled attempts to prevent sensitization through improved allergen identification, labeling, and consumer education. This review provides an overview and update on fragrance allergy. Part 1 discusses the epidemiology and evaluation of suspected fragrance allergy. Part 2 reviews screening methods, emerging fragrance allergens, and management of patients with fragrance contact allergy. This review concludes by examining recent legislation on fragrances and suggesting potential additions to screening series to help prevent and detect fragrance allergy.

  16. Cobalt sensitization and dermatitis

    DEFF Research Database (Denmark)

    Thyssen, Jacob P

    2012-01-01

    : This clinical review article presents clinical and scientific data on cobalt sensitization and dermatitis. It is concluded that cobalt despite being a strong sensitizer and a prevalent contact allergen to come up on patch testing should be regarded as a very complex metal to test with. Exposure...... data together with clinical data from metal workers heavily exposed to cobalt suggest that patch-test reactions are sometimes false positive and that patch testers should carefully evaluate their clinical relevance....

  17. Occupational protein contact dermatitis.

    Science.gov (United States)

    Barbaud, Annick; Poreaux, Claire; Penven, Emmanuelle; Waton, Julie

    2015-01-01

    Occupational contact dermatitis is generally caused by haptens but can also be induced by proteins causing mainly immunological contact urticaria (ICU); chronic hand eczema in the context of protein contact dermatitis (PCD). In a monocentric retrospective study, from our database, only 31 (0.41%) of patients with contact dermatitis had positive skin tests with proteins: 22 had occupational PCD, 3 had non-occupational PCD, 5 occupational ICU and 1 cook had a neutrophilic fixed food eruption (NFFE) due to fish. From these results and analysis of literature, the characteristics of PCD can be summarized as follows. It is a chronic eczematous dermatitis, possibly exacerbated by work, suggestive if associated with inflammatory perionyxix and immediate erythema with pruritis, to be investigated when the patient resumes work after a period of interruption. Prick tests with the suspected protein-containing material are essential, as patch tests have negative results. In case of multisensitisation revealed by prick tests, it is advisable to analyse IgE against recombinant allergens. A history of atopy, found in 56 to 68% of the patients, has to be checked for. Most of the cases are observed among food-handlers but PCD can also be due to non-edible plants, latex, hydrolysed proteins or animal proteins. Occupational exposure to proteins can thus lead to the development of ICU. Reflecting hypersensitivity to very low concentrations of allergens, investigating ICU therefore requires caution and prick tests should be performed with a diluted form of the causative protein-containing product. Causes are food, especially fruit peel, non-edible plants, cosmetic products, latex, animals.

  18. Pediatric contact dermatitis

    OpenAIRE

    Sharma Vinod; Asati Dinesh

    2010-01-01

    Allergic contact dermatitis (ACD) in children, until recently, was considered rare. ACD was considered as a disorder of the adult population and children were thought to be spared due to a lack of exposure to potential allergens and an immature immune system. Prevalence of ACD to even the most common allergens in children, like poison ivy and parthenium, is relatively rare as compared to adults. However, there is now growing evidence of contact sensitization of the pediatric population, and i...

  19. Pediatric contact dermatitis.

    Science.gov (United States)

    Sharma, Vinod K; Asati, Dinesh P

    2010-01-01

    Allergic contact dermatitis (ACD) in children, until recently, was considered rare. ACD was considered as a disorder of the adult population and children were thought to be spared due to a lack of exposure to potential allergens and an immature immune system. Prevalence of ACD to even the most common allergens in children, like poison ivy and parthenium, is relatively rare as compared to adults. However, there is now growing evidence of contact sensitization of the pediatric population, and it begins right from early childhood, including 1-week-old neonates. Vaccinations, piercing, topical medicaments and cosmetics in younger patients are potential exposures for sensitization. Nickel is the most common sensitizer in almost all studies pertaining to pediatric contact dermatitis. Other common allergens reported are cobalt, fragrance mix, rubber, lanolin, thiomersol, neomycin, gold, mercapto mix, balsum of Peru and colophony. Different factors like age, sex, atopy, social and cultural practices, habit of parents and caregivers and geographic changes affect the patterns of ACD and their variable clinical presentation. Patch testing should be considered not only in children with lesions of a morphology suggestive of ACD, but in any child with dermatitis that is difficult to control.

  20. Interstitial Granulomatous Dermatitis (IGD

    Directory of Open Access Journals (Sweden)

    Tiberiu Tebeica

    2017-07-01

    Full Text Available We report the case of a 42 years old male patient suffering from skin changes , which appeared in the last 7-8 years.  Two biopsies were performed during the evolution of the lesion. Both showed similar findings that consisted in a busy dermis with interstitial, superficial and deep infiltrates of lymphocytes and histiocytes dispersed among collagen bundles, with variable numbers of neutrophils scattered throughout. Some histiocytes were clustered in poorly formed granuloma that included rare giant cells, with discrete Palisades and piecemeal collagen degeneration, but without mucin deposition or frank necrobiosis of collagen. The clinical and histologic findings were supportive for interstitial granulomatous dermatitis. Interstitial granulomatous dermatitis (IGD is a poorly understood entity that was regarded by many as belonging to the same spectrum of disease or even synonym with palisaded and neutrophilic granulomatous dermatitis (PNGD. Although IGD and PNGD were usually related to connective tissue disease, mostly rheumatoid arthritis, some patients with typical histologic findings of IGD never develop autoimmune disorders, but they have different underlying conditions, such as metabolic diseases, lymphoproliferative disorders or other malignant tumours. These observations indicate that IGD and PNGD are different disorders with similar manifestations.

  1. Pediatric contact dermatitis

    Directory of Open Access Journals (Sweden)

    Sharma Vinod

    2010-01-01

    Full Text Available Allergic contact dermatitis (ACD in children, until recently, was considered rare. ACD was considered as a disorder of the adult population and children were thought to be spared due to a lack of exposure to potential allergens and an immature immune system. Prevalence of ACD to even the most common allergens in children, like poison ivy and parthenium, is relatively rare as compared to adults. However, there is now growing evidence of contact sensitization of the pediatric population, and it begins right from early childhood, including 1-week-old neonates. Vaccinations, piercing, topical medicaments and cosmetics in younger patients are potential exposures for sensitization. Nickel is the most common sensitizer in almost all studies pertaining to pediatric contact dermatitis. Other common allergens reported are cobalt, fragrance mix, rubber, lanolin, thiomersol, neomycin, gold, mercapto mix, balsum of Peru and colophony. Different factors like age, sex, atopy, social and cultural practices, habit of parents and caregivers and geographic changes affect the patterns of ACD and their variable clinical presentation. Patch testing should be considered not only in children with lesions of a morphology suggestive of ACD, but in any child with dermatitis that is difficult to control.

  2. Cheyletiella Blakei Dermatitis

    Directory of Open Access Journals (Sweden)

    Selma

    2011-12-01

    Full Text Available Cheyletiellosis (cheyletiella dermatitis is a dermatitis caused by cheyletiella mites that are seen more commonly in cats, dogs and rabbits all over the world. Cheyletiella blakei, which is naturally hosted by cats, causes infestations in people, especially who are in close contact with infested cats. The diagnosis of cheyletiellosis in humans is established by the suspicion of physician or veterinarian and demonstration of the mites in cats. If not suspected, cheyletiellosis may be thought as delusions of parasitosis and may be undiagnosed. A 48-year-old woman presented to our clinic with red, pruritic papules on the chest, abdomen, arms and anterior thighs. There was no remission of the complaints of the patient after 3 days of topical corticosteroid treatment. Following more detailed examination and medical history, cheyletiellosis was suspected. The diagnosis was confirmed by a veterinary control of the cat that the women had started feeding at home about 15 days ago. Although cheyletiella dermatitis is not uncommon, most cases are undiagnosed because it is not a well-known dermatosis by dermatologists. As far as we know, there is no previously reported cheyletiella case in our country. (Turk­derm 2011; 45: 213-5

  3. Allergic contact dermatitis from ethyl chloride and benzocaine.

    Science.gov (United States)

    Carazo, Juan Luis Anguita; Morera, Blanca Sáenz de San Pedro; Colom, Luis Palacios; Gálvez Lozano, José Manuel

    2009-01-01

    Ethyl chloride (EC) or chloroethane (C2H5Cl) is a volatile halogenated hydrocarbon. Reports of contact sensitivity to this gas are infrequent considering its widespread use as a local anesthetic, and it may have a relatively low sensitization potential. Benzocaine is another local anesthetic derivative of the ethyl ester of para-aminobenzoic acid, previously reported as a causative agent of delayed hypersensitivity reactions. We present a patient who developed a generalized itching dermatitis after the application of a medical aerosol containing EC, as well as facial angioedema and tongue swelling after the local application of benzocaine. Patch-test results were positive for EC "as is" (++), benzocaine 5% in petrolatum (++), and caine mix (+++) at 96 hours (day 4). The possibility of cross-sensitization between both drugs would not have been chemically plausible. We report the first published clinical case of contact allergic dermatitis from two chemically unrelated local anesthetics (EC and benzocaine) in the same patient.

  4. Sofa dermatitis presenting as a chronic treatment resistant dermatitis.

    LENUS (Irish Health Repository)

    Lynch, M

    2010-04-01

    There is now a well publicised increase in cases of sofa dermatitis since 2007. These have been linked to allergic contact sensitization to dimethlylfumarate, a novel contact allergen. We report on a case associated with a two year history of a treatment resistant dermatitis.

  5. Clinical comparison of human and canine atopic dermatitis using human diagnostic criteria (Japanese Dermatological Association, 2009): proposal of provisional diagnostic criteria for canine atopic dermatitis.

    Science.gov (United States)

    Terada, Yuri; Nagata, Masahiko; Murayama, Nobuo; Nanko, Hiroko; Furue, Masutaka

    2011-08-01

    Atopic dermatitis (AD) is a common skin disease encountered in both humans and dogs. Canine AD can be used in the analysis of naturally occurring AD; however, details of clinical comparison have been lacking. The purpose of this study is to compare those clinical features using the human diagnostic criteria (Japanese Dermatological Association, 2009). Fifty-one dogs with canine AD were evaluated by the human criteria. Prior to this study, canine AD was basically diagnosed by the fulfillment of two authentic canine AD criteria and a positive reaction against Dermatophagoides farinae in serum immunoglobulin E levels and/or in intradermal tests. Among the human AD criteria items, behavior corresponding to pruritus was observed in all 51 dogs. Skin lesions corresponding to eczematous dermatitis were seen in 50 dogs, and symmetrical distribution of skin lesions was noted in all 51 dogs. A chronic or chronically relapsing course was observed in 50 dogs. Based on these results, the concordance rate for the criteria was 96% (49/51). Differential diagnoses of AD were also investigated in the same manner. The concordance rate for the criteria was 0% (0/69) in scabies, 2% (1/50) in pyoderma, 0% (0/50) in demodicosis, 0% (0/9) in cutaneous lymphoma, 0% (0/2) in ichthyosis, 25% (2/7) in flea allergy, 48% (24/50) in seborrheic dermatitis and 75% (3/4) in food allergy. Canine AD is thus indicated as a valuable counterpart to human AD in clinical aspects. In addition, the human AD criteria could be applicable, with some modification, as provisional diagnostic criteria for canine AD.

  6. 复方甘草酸苷片联合胶原蛋白面膜治疗面部激素依赖性皮炎80例疗效观察%Efficacy observation on glycyrrhizin tablets joint collagen facial mask treatment of 80 ca-ses Hormone-Dependent Dermatitis

    Institute of Scientific and Technical Information of China (English)

    张红明; 李静; 孙嘉俊; 王雪松

    2014-01-01

    AIM:To observe treatment effect of facial glycyrrhi-zin tablets joint collagen mask on Hormone-Dependent Dermatitis and to provide clinical help and guidance.METHODS:The 80 cases of our hospital from June 2013 to June 2014 with Hormone-Dependent Dermatitis were randomly divided into treatment group and control group.The control group received collagen mask treat-ment,20 ~30 min /time,one time /day,continuously use of two weeks;treatment group received collagen mask treatment based on the use of glycyrrhizin tablets (named Paiganneng,Lijun Pharmaceutical)2 tablets/time,3 times/day,orally.After 6 weeks' treatment efficacy of the two groups were observed.RE-SULTS:In the control group,the total effective rate was 45%, while the treatment group was up to 87.5%,the difference was statistically significant (P<0.05).Two groups of patients' cured rate,valid rate,invalid rate,had statistically significant differ-ence (χ2 =16.1565,P<0.01).The control group and the treat-ment group each had three cases of patients with symptoms of a slight decrease in serum potassium,oral potassium remission. CONCLUSION:Glycyrrhizin tablets joint collagen dressings mask for the treatment of Hormone-Dependent Dermatitis,can not only improve the skin symptoms,but also increase the anti-in-flammatory and anti-allergic effects,two drugs used in combina-tion can improve the therapeutic effect,and reduce the incidence of adverse reactions.%目的:观察复方甘草酸苷片联合胶原蛋白面膜治疗面部激素依赖性皮炎的效果,为临床提供帮助和指导.方法:将我院2013-06/2014-06皮肤科门诊收治的80例面部激素依赖性皮炎患者随机分为治疗组和对照组,对照组给予胶原蛋白面膜治疗,20~30 min/次,1次/d,连续使用两周;治疗组在对照组胶原蛋白面膜治疗基础上加用复方甘草酸苷片(商品名派甘能、丽君制药)2片/次、3次/d,口服.治疗6周后,观察两组

  7. Canadian hand dermatitis management guidelines

    DEFF Research Database (Denmark)

    Lynde, Charles; Guenther, Lyn; Diepgen, Thomas L;

    2010-01-01

    Hand dermatitis (HD) is one of the most common skin conditions; however, it is not a homogeneous disease entity. The severity of HD may range from very mild cases to severe chronic forms, which may result in prolonged disability and, occasionally, refractory HD. Chronic hand dermatitis (CHD...

  8. Livedoid Dermatitis Treated With Nifedipine

    Directory of Open Access Journals (Sweden)

    Lee Wheless MD, PhD

    2016-02-01

    Full Text Available Intravenous injection of buprenorphine as a cause of livedoid dermatitis is a recently described phenomenon. This report reviews the brief literature of this finding, and presents a case of livedoid dermatitis of both heels following injection more than one day prior, and thesuccessful treatment with nifedipine monotherapy.

  9. Atopic dermatitis and ichthyosis vulgaris.

    Science.gov (United States)

    Rabinowitz, L G; Esterly, N B

    1994-06-01

    Atopic dermatitis remains a common skin problem in the pediatric age group. General approaches to management focus on reducing inflammation and pruritus as well as preventing xerosis. Ichthyosis vulgaris is the most common form of the ichthyoses and often is associated with atopic dermatitis. Recognition of these conditions is necessary to institute therapy that will alleviate the discomfort experienced by affected individuals.

  10. Canadian hand dermatitis management guidelines

    DEFF Research Database (Denmark)

    Lynde, Charles; Guenther, Lyn; Diepgen, Thomas L

    2010-01-01

    Hand dermatitis (HD) is one of the most common skin conditions; however, it is not a homogeneous disease entity. The severity of HD may range from very mild cases to severe chronic forms, which may result in prolonged disability and, occasionally, refractory HD. Chronic hand dermatitis (CHD) is a...

  11. Recurrent dermatitis from jellyfish envenomation.

    OpenAIRE

    Menahem, S; Shvartzman, P.

    1994-01-01

    Jellyfish envenomation can cause an immediate local skin reaction, which is usually a painful linear vesiculourticarial eruption. Persistent, delayed, or recurrent dermatitis is less common. Because jellyfish sting reactions and their management are unfamiliar to family physicians, we describe a case of recurrent local dermatitis after jellyfish envenomation and suggest appropriate treatment.

  12. Nodulocystic basal cell carcinoma arising directly from a seborrheic keratosis: A rare case report

    Directory of Open Access Journals (Sweden)

    Kana Shibao

    2016-01-01

    Full Text Available Seborrheic keratoses (SKs are common epidermal tumors composed of benign keratinocytes. Malignant skin tumors including basal cell carcinoma (BCC rarely arise within SKs. We report a rare case of an 82-year-old man with nodulocystic BCC that appeared at the center of a scaly hyperpigmented SK that had been presented for more than 10 years. It was histologically confirmed that CK19-positive BCC arose directly from the wall of the pseudohorn cyst, a part of the SK. Nodular and/or cystic BCC also rarely arise within SKs while the most common histologic type of BCC within SKs is the superficial type. Careful observation of SKs is important even though it is rarely a background condition for malignant transformation.

  13. Contact dermatitis in military personnel.

    Science.gov (United States)

    Dever, Tara T; Walters, Michelle; Jacob, Sharon

    2011-01-01

    Military personnel encounter the same allergens and irritants as their civilian counterparts and are just as likely to develop contact dermatitis from common exposures encountered in everyday life. In addition, they face some unique exposures that can be difficult to avoid owing to their occupational duties. Contact dermatitis can be detrimental to a military member's career if he or she is unable to perform core duties or avoid the inciting substances. An uncontrolled contact dermatitis can result in the member's being placed on limited-duty (ie, nondeployable) status, needing a job or rate change, or separation from military service. We present some common causes of contact dermatitis in military personnel worldwide and some novel sources of contact dermatitis in this population that may not be intuitive.

  14. [Intraepidermal mass of M. leprae in a case of seborrheic keratosis due to Hansen's disease (LLs)].

    Science.gov (United States)

    Yajima, M; Suzuki, K; Wen, M; Yamada, N; Asano, G

    1995-11-01

    A 67-year-old patient has had exanthema in the lower right limb since 51 years ago (16 years old at onset), which underwent repeated remission and recurrence. At present, he has bilateral symmetrical widespread infiltrating exanthema and asymmetrical marked neuralhypertrophy, and has been diagnosed typical LLs (His father had the same disease). The exanthema recurred several years ago, and the patient is being treated for Hansen's disease. He had a dark brown flat elevation with a rough surface and the size of a small finger tip in his right abdominal skin for approximately 20 years. A biopsy was performed, and the specimen was fixed in 10% formalin and paraffin sections were prepared for histopathologic examination. A part of the specimen was processed forscanning electron microscopic examination. Seborrheic keratosis was diagnosed by H & E staining. Acid-fast (FITE) staining, immunohistochemical staining (keratin, S-100 protein, anti-PGL antibody and anti-BCG antibody) and scanning electron microscopy revealed the presence of bacteria (M. leprae) in the dermal foam cells, the matrix with a banded structure and the squamous epithelial cells which normally lack phagocytosis function. Compared to the basal cells of normal epidermis, the basal cells located adjacent to the dermis affected with seborrheic keratosis showed increased proliferation and more marked characteristics of a germinative cell. The degree of differentiation of the basal cells appeared regressed, and they probably possessed augmented phagocytic activity. The phagocytosed bacteria were probably carried by the epidermal cell cycle toward the surface layer. However, bacteria could not be found in the stratum corneum, probably due to an association with the lysosome.

  15. EFFECTIVENESS AND SAFETY OF PIMECROLIMUS IN TREATMENT OF ATOPIC DERMATITIS IN CHILDREN AND ADOLESCENTS

    Directory of Open Access Journals (Sweden)

    K.N. Monakhov

    2008-01-01

    Full Text Available The results of treatment of 57 patients with atopic dermatitis (ATD in age 7–18 years old with elidel cream are described. Cream was drifted on facial skin 2 times daily. Apparent effect was marked on 7–14 day. There was no any case of serious adverse events. Thus, taking to account safety and effectiveness profile, pimecrolimus can be used as a medication of first line of therapy in treatment of ATD, while lesion is located on sensitive sectors of skin.Key words: children, atopic dermatitis, pimecrolimus.

  16. Ectodermal dysplasias associated with clefting: significance of scalp dermatitis.

    Science.gov (United States)

    Fosko, S W; Stenn, K S; Bolognia, J L

    1992-08-01

    Several clinical syndromes are characterized by ectodermal dysplasia (ED) in association with clefting of the lip and/or palate. The three most commonly recognized entities are (1) the EEC syndrome (ectodermal dysplasia, ectrodactyly, cleft lip/palate); (2) the Rapp-Hodgkin syndrome with ectodermal dysplasia, cleft lip/palate, and mid facial hypoplasia; and (3) the Hay-Wells or AEC syndrome (ankyloblepharon, ectodermal defects, cleft lip/palate). The clinical characteristics of these entities as well as several less common syndromes are reviewed and summarized. The presence of scalp dermatitis in patients with the AEC syndrome and less often the Rapp-Hodgkin syndrome is emphasized.

  17. Contact dermatitis to methylisothiazolinone*

    Science.gov (United States)

    Scherrer, Maria Antonieta Rios; Rocha, Vanessa Barreto; Andrade, Ana Regina Coelho

    2015-01-01

    Methylisothiazolinone (MI) is a preservative found in cosmetic and industrial products. Contact dermatitis caused by either methylchloroisothiazolinone/methylisothiazolinone (MCI/MI or Kathon CG) or MI has shown increasing frequency. The latter is preferably detected through epicutaneous testing with aqueous MI 2000 ppm, which is not included in the Brazilian standard tray. We describe a series of 23 patients tested using it and our standard tray. A case with negative reaction to MCI/MI and positive to MI is emphasized. PMID:26734880

  18. Pediatric facial nerve rehabilitation.

    Science.gov (United States)

    Banks, Caroline A; Hadlock, Tessa A

    2014-11-01

    Facial paralysis is a rare but severe condition in the pediatric population. Impaired facial movement has multiple causes and varied presentations, therefore individualized treatment plans are essential for optimal results. Advances in facial reanimation over the past 4 decades have given rise to new treatments designed to restore balance and function in pediatric patients with facial paralysis. This article provides a comprehensive review of pediatric facial rehabilitation and describes a zone-based approach to assessment and treatment of impaired facial movement.

  19. Dermatitis artefacta: a review.

    Science.gov (United States)

    Rodríguez Pichardo, A; García Bravo, B

    2013-12-01

    Dermatitis artefacta is a rarely diagnosed disorder that is often a source of perplexity and anxiety for dermatologists because they know less about the cause of this self-inflicted condition than the patients themselves. It differs from other skin disorders in that diagnosis is made by exclusion rather than on the basis of histologic and biochemical findings and therefore involves a considerable investment of time and resources. Based on the findings of a study of 201 patients diagnosed with dermatitis artefacta between 1976 and 2006, we review the different clinical presentations of this skin disorder and discuss its diagnosis and treatment. The series analyzed comprised 152 women and 49 men (female to male ratio of 3.1:1) with a mean age of 31.2 years. The patients were mostly single and had a low educational level and few or no job qualifications or skills. Copyright © 2011 Elsevier España, S.L. and AEDV. All rights reserved.

  20. Dermoscopic Features of Facial Pigmented Skin Lesions

    Science.gov (United States)

    Goncharova, Yana; Attia, Enas A. S.; Souid, Khawla; Vasilenko, Inna V.

    2013-01-01

    Four types of facial pigmented skin lesions (FPSLs) constitute diagnostic challenge to dermatologists; early seborrheic keratosis (SK), pigmented actinic keratosis (AK), lentigo maligna (LM), and solar lentigo (SL). A retrospective analysis of dermoscopic images of histopathologically diagnosed clinically-challenging 64 flat FPSLs was conducted to establish the dermoscopic findings corresponding to each of SK, pigmented AK, LM, and SL. Four main dermoscopic features were evaluated: sharp demarcation, pigment pattern, follicular/epidermal pattern, and vascular pattern. In SK, the most specific dermoscopic features are follicular/epidermal pattern (cerebriform pattern; 100% of lesions, milia-like cysts; 50%, and comedo-like openings; 37.50%), and sharp demarcation (54.17%). AK and LM showed a composite characteristic pattern named “strawberry pattern” in 41.18% and 25% of lesions respectively, characterized by a background erythema and red pseudo-network, associated with prominent follicular openings surrounded by a white halo. However, in LM “strawberry pattern” is widely covered by psewdonetwork (87.5%), homogenous structureless pigmentation (75%) and other vascular patterns. In SL, structureless homogenous pigmentation was recognized in all lesions (100%). From the above mentioned data, we developed an algorithm to guide in dermoscopic features of FPSLs. PMID:23431466

  1. Facial Scar Revision: Understanding Facial Scar Treatment

    Science.gov (United States)

    ... more to fully heal and achieve maximum improved appearance. Facial plastic surgery makes it possible to correct facial flaws that can undermine self-confidence. Changing how your scar looks can help change ...

  2. Facial attractiveness: General patterns of facial preferences

    National Research Council Canada - National Science Library

    Kościński, Krzysztof

    2007-01-01

    This review covers universal patterns in facial preferences. Facial attractiveness has fascinated thinkers since antiquity, but has been the subject of intense scientific study for only the last quarter of a century...

  3. [Surgical facial reanimation after persisting facial paralysis].

    Science.gov (United States)

    Pasche, Philippe

    2011-10-01

    Facial reanimation following persistent facial paralysis can be managed with surgical procedures of varying complexity. The choice of the technique is mainly determined by the cause of facial paralysis, the age and desires of the patient. The techniques most commonly used are the nerve grafts (VII-VII, XII-VII, cross facial graft), dynamic muscle transfers (temporal myoplasty, free muscle transfert) and static suspensions. An intensive rehabilitation through specific exercises after all procedures is essential to archieve good results.

  4. Facial porokeratosis.

    Science.gov (United States)

    Carranza, Dafnis C; Haley, Jennifer C; Chiu, Melvin

    2008-01-01

    A 34-year-old man from El Salvador was referred to our clinic with a 10-year history of a pruritic erythematous facial eruption. He reported increased pruritus and scaling of lesions when exposed to the sun. He worked as a construction worker and admitted to frequent sun exposure. Physical examination revealed well-circumscribed erythematous to violaceous papules with raised borders and atrophic centers localized to the nose (Figure 1). He did not have lesions on the arms or legs. He did not report a family history of similar lesions. A biopsy specimen was obtained from the edge of a lesion on the right ala. Histologic examination of the biopsy specimen showed acanthosis of the epidermis with focal invagination of the corneal layer and a homogeneous column of parakeratosis in the center of that layer consistent with a cornoid lamella (Figure 2). Furthermore, the granular layer was absent at the cornoid lamella base. The superficial dermis contained a sparse, perivascular lymphocytic infiltrate. No evidence of dysplasia or malignancy was seen. These findings supported a diagnosis of porokeratosis. The patient underwent a trial of cryotherapy with moderate improvement of the facial lesions.

  5. Dermatitis recall during disulfiram therapy

    Directory of Open Access Journals (Sweden)

    Zawar Vijay

    2004-01-01

    Full Text Available We report an alcoholic Indian man, a known case of contact dermatitis to nickel, who presented with recurrence at the same site, without having recent contact with nickel, following disulfiram therapy for his alcohol addiction.

  6. Dermatitis herpetiformis and rheumatoid arthritis

    Directory of Open Access Journals (Sweden)

    Singal Archana

    2002-01-01

    Full Text Available A 35- year-old deaf and dumb woman with clinical and histopothological diagnosis of dermatitis herpetiforrnis (DH is reported for its rare association with rheumatoid arthritis (PA.

  7. Occupational contact dermatitis in hairdressers

    DEFF Research Database (Denmark)

    Schwensen, Jakob F; Johansen, Jeanne Duus; Veien, Niels K

    2013-01-01

    BACKGROUND: Occupational contact dermatitis among hairdressers is frequent, owing to daily exposure to irritants and allergens. OBJECTIVES: To identify sensitization to the most common allergens associated with the occupation of hairdressing. METHODS: Patch test results of 399 hairdressers and 19...

  8. Genetics Home Reference: atopic dermatitis

    Science.gov (United States)

    ... KidsHealth from Nemours: Eczema MalaCards: atopic dermatitis Merck Manual Consumer Version The University of Chicago Medicine World Allergy Organization: The Allergic March Patient Support and Advocacy Resources ( ...

  9. Dendritic cells and contact dermatitis.

    Science.gov (United States)

    Sasaki, Yoshinori; Aiba, Setsuya

    2007-10-01

    Contact dermatitis is a biological response to simple chemicals in the skin. Although it is well known that allergic contact dermatitis is mediated by the immune system, it is still uncertain whether it is a kind of protective response or it is simply an unnecessary response. We have demonstrated the following: (1) haptens activate Langerhans cells in the initiation phase of murine allergic contact dermatitis in vivo, (2) haptens activate human monocyte-derived dendritic cells in vitro, (3) the activation of dendritic cells by haptens is primarily mediated by the activation of p38 mitogen-activated protein kinase (MAPK), and (4) the activation of p38 MAPK is mediated by stimulation related to an imbalance of intracellular redox. Based on these observations, we will discuss the biological significance of contact dermatitis. In addition, we will review some up-to-date findings on Langerhans cell biology.

  10. New insights into atopic dermatitis

    National Research Council Canada - National Science Library

    Leung, Donald Y M; Boguniewicz, Mark; Howell, Michael D; Nomura, Ichiro; Hamid, Qutayba A

    2004-01-01

    Atopic dermatitis is a chronic inflammatory skin disease associated with cutaneous hyperreactivity to environmental triggers and is often the first step in the atopic march that results in asthma and allergic rhinitis...

  11. Contact dermatitis in a woodworker.

    Science.gov (United States)

    Correale, Christine E; Marks, James G

    2002-03-01

    Woods are capable of causing allergic or irritant contact dermatitis which typically occurs on the exposed areas of the arms, face, and neck. The allergens found in woods include quinones, stilbenes, phenols, and terpenes. We report an 84-year-old woodworker who developed allergic contact dermatitis from Bolivian rosewood and Cocobolo wood. The patient was patch-tested using the North American Contact Dermatitis Group Standard Tray; 2,6 dimethoxyl 1,4 benzoquinone; and wood that he had been exposed to on a regular basis. Positive patch test reactions occurred to methyldibromo glutaronitrile phenoxyethanol, sodium gold thiosulfate, Bolivian rosewood, and Cocobolo wood. Allergens found in Bolivian rosewood and Cocobolo wood caused this patient's chronic dermatitis, which cleared when he avoided these woods. Copyright 2002, Elsevier Science (USA). All rights reserved.

  12. [Occupational contact dermatitis in hairdressers].

    Science.gov (United States)

    Kieć-Swierczyńska, Marta; Krycisz, Beata; Chomiczewska, Dorota

    2009-01-01

    Numerous data from the medical literature show that working as a hairdresser is associated with the highest risk of occupational contact dermatitis. In Europe, hairdressers rank first of all occupation groups with the highest prevalence of occupational dermatitis. It is estimated that 10-20% and even 50% of hairdressers are affected with skin disorders. Skin problems occur soon after commencing hairdressing, in the first 2 years of work, sometimes during vocational training. The most common factors contributing to skin damage include water, shampoos, detergents, conditioners, hair dyes, bleaches, permanent wave solutions and components of gloves. Water and wet work are prime skin irritants - causal factors of irritant contact dermatitis while p-phenylenediamine, glyceryl monothioglycolate, ammonium persulfate and also fragrances, preservatives, disinfectants and metals are the most important allergens, which induce allergic contact dermatitis.

  13. Contact dermatitis to Alstroemeria.

    Science.gov (United States)

    Santucci, B; Picardo, M; Iavarone, C; Trogolo, C

    1985-04-01

    A study was carried out on 50 workers in a floriculture centre to evaluate the incidence of contact dermatitis to Alstroemeria. 3 subjects gave positive reactions to aqueous and ethanolic extracts of cut flowers, stems and leaves. By column chromatography, the allergen was isolated and its chemical structure identified as 6-tuliposide A by proton magnetic resonance and carbon-13 magnetic resonance. Only 6-tuliposide A was isolated from cut flowers, and this gave positive reactions when patch tested at 0.01%; a-methylene-gamma-butyrolactone at 10(-5) (v/v) was positive in the same 3 subjects. Other lactones (gamma-methylene-gamma-butyrolactone, alantolactone, isoalantolactone) were negative at all concentrations used.

  14. Allergic contact dermatitis to Alstroemeria.

    Science.gov (United States)

    Marks, J G

    1988-06-01

    Two female florists developed dermatitis of the fingertips. Patch testing revealed allergic contact dermatitis to the flower, Alstroemeria, used in floral arrangements. They had positive patch tests to portions of Alstroemeria, and to tuliposide A, the allergen in this plant. Vinyl gloves were not helpful since tuliposide A readily penetrates through these gloves. Nitrile gloves may be protective since they prevented positive patch test to tuliposide A.

  15. Contact dermatitis to botanical extracts.

    Science.gov (United States)

    Kiken, David A; Cohen, David E

    2002-09-01

    A review of the literature of reported cases of contact dermatitis to a variety of natural herbal extracts is Presented. Natural extracts are commonly used ingredients in many cosmetic preparations and homeopathic remedies. Although the term natural botanical extracts inherently purports to have beneficial and benign properties, these extracts can cause adverse reactions in individuals. As such, dermatologists should be cognizant of these agents as possible sources of allergenicity in patients presenting with contact dermatitis.

  16. Ezcema herpeticatum and dermatitis atopica

    Directory of Open Access Journals (Sweden)

    I. Drljević

    2005-02-01

    Full Text Available This paper shows a case of eczema herpeticatum associated with dermatitis atopica in a two-year-old boy. Eczema herpeticatum was developed as a complication due to irregular topical treatment of atopic dermatitis for a longer period of time (up to 5 months. The boy was initially treated with a few types of topical steroids, and then with topical immune suppressant (pimecrolimus 1% cream. The diagnosis has been confirmed by family history of allergic disorders, clinical and laboratory findings.

  17. Measuring Facial Movement

    Science.gov (United States)

    Ekman, Paul; Friesen, Wallace V.

    1976-01-01

    The Facial Action Code (FAC) was derived from an analysis of the anatomical basis of facial movement. The development of the method is explained, contrasting it to other methods of measuring facial behavior. An example of how facial behavior is measured is provided, and ideas about research applications are discussed. (Author)

  18. Facial Recognition

    Directory of Open Access Journals (Sweden)

    Mihalache Sergiu

    2014-05-01

    Full Text Available During their lifetime, people learn to recognize thousands of faces that they interact with. Face perception refers to an individual's understanding and interpretation of the face, particularly the human face, especially in relation to the associated information processing in the brain. The proportions and expressions of the human face are important to identify origin, emotional tendencies, health qualities, and some social information. From birth, faces are important in the individual's social interaction. Face perceptions are very complex as the recognition of facial expressions involves extensive and diverse areas in the brain. Our main goal is to put emphasis on presenting human faces specialized studies, and also to highlight the importance of attractiviness in their retention. We will see that there are many factors that influence face recognition.

  19. Contact Dermatitis, Patch Testing, and Allergen Avoidance.

    Science.gov (United States)

    Burkemper, Nicole M

    2015-01-01

    In patients presenting with a complaint of rash, contact dermatitis is often the underlying diagnosis making it an entity with which health care providers should be familiar. Contact dermatitis can be divided into irritant contact dermatitis and allergic contact dermatitis. In a patient suspected of having allergic contact dermatitis, patch testing can be done to identify specific allergens. Education focused on allergen avoidance and safe products is an integral part of treatment for the contact dermatitis patient. Knowledge of the most common allergens is helpful for clinicians to be able to provide this education.

  20. [Peripheral facial nerve palsy].

    Science.gov (United States)

    Pons, Y; Ukkola-Pons, E; Ballivet de Régloix, S; Champagne, C; Raynal, M; Lepage, P; Kossowski, M

    2013-06-01

    Facial palsy can be defined as a decrease in function of the facial nerve, the primary motor nerve of the facial muscles. When the facial palsy is peripheral, it affects both the superior and inferior areas of the face as opposed to central palsies, which affect only the inferior portion. The main cause of peripheral facial palsies is Bell's palsy, which remains a diagnosis of exclusion. The prognosis is good in most cases. In cases with significant cosmetic sequelae, a variety of surgical procedures are available (such as hypoglossal-facial anastomosis, temporalis myoplasty and Tenzel external canthopexy) to rehabilitate facial aesthetics and function.

  1. 薏苡仁为主治疗脂溢性痤疮%Investigation of Yiyiren as Remedium Cardinale in the Treat of Seborrheic Ache

    Institute of Scientific and Technical Information of China (English)

    候小亮; 崔应珉

    2012-01-01

    Objective:Investigate the effect of Yiyiren as remedium cardinale in the treat of seborrheic acne. Methods;Use Yiyiren as re-medium cardinal in the treatment of seborrheic acne according to TCM differentiation - treatment. Results: Seborrheic acne is mainly because of splenogastric hygropyrexia and hair follicle blocking by moisture blocking. Yiyiren as remedium cardinal in the treatment of seborrheic acne has evident effect. Conclusion; YiyiRen has satisfied curative effect for seborrheic acne so that the mechanism needs further study.%目的:探讨以薏苡仁为主药治疗脂溢性痤疮的效果.方法:采用中医辨证论治的方法,重用薏苡仁,治疗典型脂溢性痤疮症.结果:脂溢性痤疮主要是由于脾胃湿热上炎,湿气排出不畅堵塞毛囊引起,通过重用薏苡仁能使患者的临床病症得到改善,疗效显著.结论:薏苡仁治疗脂溢性痤疮疗效满意,其机理有待进一步研究.

  2. Traditional Smallpox Vaccines and Atopic Dermatitis

    Science.gov (United States)

    ... Trials 2016 Research Grant Request DONATE Traditional Smallpox Vaccines and Atopic Dermatitis Frequently Asked Questions Eczema Living ... Involved Eczema Products News Research Donate Traditional Smallpox Vaccines and Atopic Dermatitis Frequently Asked Questions What is ...

  3. Atopic dermatitis: tacrolimus vs. topical corticosteroid use

    African Journals Online (AJOL)

    Atopic dermatitis (AD) is an inflammatory skin disease that is characterised by extreme ..... extreme cases, Cushing syndrome.5,12,16,17 However, there is no conclusive .... The diagnosis and management of atopic dermatitis. S Afr. Fam Pract.

  4. Neuropeptides in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    M. Cholis

    2001-09-01

    Full Text Available The nervous system, the immune system, and the cutaneous system are not independent systems, but are closely associated and use the same language of cytokines and neurotransmitters. Atopic dermatitis (AD is exacerbated by several factors, such as emotional stress, scratching and sweating. This review presents the role of neuropeptides (NP in AD. In AD, abnormalities occur in distribution of some types of neural filaments and in the associated active NP. Nerve fibre increases. Nerve fibres for substance-P (SP and calcitonin gene-related peptide (CGRP are positive, The cutaneous concentration of SP decreases while vasoactive-intestinal polypeptide (VIP increases. Immunohistochemical examination has revealed neuropeptide-Y (NPY-positive dendritic epidermal cells in AD lesions but no somatostatin (SOM fibres. Neuromediators modulate functions of all cutaneous cellular types, which are all part of the neuroimmunocutaneous system (NCIS: endothelial cells, glandular cells, fibroblasts, epidermal cells and immune cells. Conclusion: during the course of AD, the NICS is destabilized. Evidence show that NP can also be responsible for the induction and maintenance of the cutaneous inflammation process and confirm an involvement in the pathogenesis of AD. Release of the NP by cutaneous nerve potentially explains the role of emotional stress, scratching and sweating in exacerbation of AD. (Med J Indones 2001; 10: 197-200Keywords : neuroimmunocutaneous system, neurotransmitter, neurogenic inflammation

  5. Systemic contact dermatitis

    Directory of Open Access Journals (Sweden)

    Daria Nowak

    2016-02-01

    Full Text Available Systemic contact dermatitis (SCD is a skin inflammation occurring in a patient after systemic administration of a hapten, which previously caused an allergic contact skin reaction in the same person. Most frequently, hypersensitivity reactions typical for SCD occur after absorption of haptens with food or inhalation. Haptens occur mainly in the forms of metals and compounds present in natural resins, preservatives, food thickeners, flavorings and medicines. For many years, several studies have been conducted on understanding the pathogenesis of SCD in which both delayed type hypersensitivity (type IV and immediate type I are observed. Components of the complement system are also suspected to attend there. Helper T cells (Th (Th1 and Th2, cytotoxic T lymphocytes (Tc, and NK cells play a crucial role in the pathogenesis of SCD. They secrete a number of pro-inflammatory cytokines. In addition, regulatory T cells (Tregs have an important role. They control and inhibit activity of the immune system during inflammation. Tregs release suppressor cytokines and interact directly with a target cell through presentation of immunosuppressive particles at the cell surface. Diagnostic methods are generally the patch test, oral provocation test, elimination diet and lymphocyte stimulation test. There are many kinds of inflammatory skin reactions caused by systemic haptens’ distribution. They are manifested in a variety of clinical phenotypes of the disease.

  6. [Systemic contact dermatitis].

    Science.gov (United States)

    Nowak, Daria; Gomułka, Krzysztof; Dziemieszonek, Paulina; Panaszek, Bernard

    2016-02-25

    Systemic contact dermatitis (SCD) is a skin inflammation occurring in a patient after systemic administration of a hapten, which previously caused an allergic contact skin reaction in the same person. Most frequently, hypersensitivity reactions typical for SCD occur after absorption of haptens with food or inhalation. Haptens occur mainly in the forms of metals and compounds present in natural resins, preservatives, food thickeners, flavorings and medicines. For many years, several studies have been conducted on understanding the pathogenesis of SCD in which both delayed type hypersensitivity (type IV) and immediate type I are observed. Components of the complement system are also suspected to attend there. Helper T cells (Th) (Th1 and Th2), cytotoxic T lymphocytes (Tc), and NK cells play a crucial role in the pathogenesis of SCD. They secrete a number of pro-inflammatory cytokines. In addition, regulatory T cells (Tregs) have an important role. They control and inhibit activity of the immune system during inflammation. Tregs release suppressor cytokines and interact directly with a target cell through presentation of immunosuppressive particles at the cell surface. Diagnostic methods are generally the patch test, oral provocation test, elimination diet and lymphocyte stimulation test. There are many kinds of inflammatory skin reactions caused by systemic haptens' distribution. They are manifested in a variety of clinical phenotypes of the disease.

  7. Atopic dermatitis in adolescence

    Directory of Open Access Journals (Sweden)

    Giampaolo Ricci

    2011-12-01

    Full Text Available Atopic dermatitis (AD is a chronic inflammatory skin disorder that typically occurs during childhood especially in the first year of life, with a variable frequency from 10% to 30%. Recent studies have shown that in Europe among 10-20% of children with AD suffer from this disorder also in adolescence. AD is a chronic inflammatory skin disease with a typical onset in the first years of life and with a 10- 30% prevalence among young children. AD prevalence in adolescence has been estimated around 5-15% in European countries. AD persists from childhood through adolescence in around 40% of cases and some risk factors have been identified: female sex, sensitization to inhalant and food allergens, allergic asthma and/or rhinoconjunctivitis, the practice of certain jobs. During adolescence, AD mainly appears on the face and neck, often associated with overinfection by Malassezia, and on the palms and soles. AD persistence during adolescence is correlated with psychological diseases such as anxiety; moreover, adolescents affected by AD might have problems in the relationship with their peers. Stress and the psychological problems represent a serious burden for adolescents with AD and cause a significant worsening of the patients’ quality of life (QoL. The pharmacological treatment is similar to other age groups. Educational and psychological approaches should be considered in the most severe cases.

  8. Dermatitis Herpetiformis and Vitiligo

    Directory of Open Access Journals (Sweden)

    Ozlem Karabudak

    2007-11-01

    Full Text Available Dermatitis herpetiformis (DH is a rare immunobullous disorder of the skin that is associated with gluten hypersensitivity. Subepidermal IgA-type antibody deposition against tissue transglutaminase leads to dense neutrophilic microabscess and eventually into vesicles in dermal papillae, which may occasionally merge into bullae. Being a subepidermal vesiculobullous disorder, DH is frequently associated with postinflammatory pigmentary changes, particularly hypopigmentation. However, the association of DH with true vitiligo is extremely rare. Here, we report a 21-year-old male with vitiligo and comorbid DH, and review the literature. This new case had severely pruritic, papular and papulovesicular lesions that were localized symmetrically and partly confined to the pre-existing vitiliginous areas. The skin biopsy specimen taken from an erythematous papule on the elbow showed characteristic findings of DH and vitiligo. Direct immunofluorescence microscopy of the perilesional skin revealed granular IgA deposition of dermal papillae. There are only 10 reports in the literature of DH and vitiligo comorbidity.

  9. Systemic contact dermatitis

    Directory of Open Access Journals (Sweden)

    Daria Nowak

    2016-02-01

    Full Text Available Systemic contact dermatitis (SCD is a skin inflammation occurring in a patient after systemic administration of a hapten, which previously caused an allergic contact skin reaction in the same person. Most frequently, hypersensitivity reactions typical for SCD occur after absorption of haptens with food or inhalation. Haptens occur mainly in the forms of metals and compounds present in natural resins, preservatives, food thickeners, flavorings and medicines. For many years, several studies have been conducted on understanding the pathogenesis of SCD in which both delayed type hypersensitivity (type IV and immediate type I are observed. Components of the complement system are also suspected to attend there. Helper T cells (Th (Th1 and Th2, cytotoxic T lymphocytes (Tc, and NK cells play a crucial role in the pathogenesis of SCD. They secrete a number of pro-inflammatory cytokines. In addition, regulatory T cells (Tregs have an important role. They control and inhibit activity of the immune system during inflammation. Tregs release suppressor cytokines and interact directly with a target cell through presentation of immunosuppressive particles at the cell surface. Diagnostic methods are generally the patch test, oral provocation test, elimination diet and lymphocyte stimulation test. There are many kinds of inflammatory skin reactions caused by systemic haptens’ distribution. They are manifested in a variety of clinical phenotypes of the disease.

  10. Surgical-Allogeneic Facial Reconstruction: Facial Transplants

    OpenAIRE

    Marcelo Coelho Goiato; Daniela Micheline Dos Santos; Lisiane Cristina Bannwart; Marcela Filié Haddad; Leonardo Viana Pereira; Aljomar José Vechiato Filho

    2014-01-01

    Several factors including cancer, malformations and traumas may cause large facial mutilation. These functional and aesthetic deformities negatively affect the psychological perspectives and quality of life of the mutilated patient. Conventional treatments are prone to fail aesthetically and functionally. The recent introduction of the composite tissue allotransplantation (CTA), which uses transplanted facial tissues of healthy donors to recover the damaged or non-existent facial tissue of mu...

  11. Overexpression of linker for activated T cells, cyclooxygenase-2, CD1a, CD68 and myeloid/histiocyte antigen in an inflamed seborrheic keratosis

    Directory of Open Access Journals (Sweden)

    Ana Maria Abreu-Velez

    2011-01-01

    Full Text Available Context: Inflamed seborrheic keratoses are generally associated with the accumulation of variable numbers of lymphocytes and histiocytes in the superficial dermis. The precise immunologic mechanism of this histologic phenomenon is not known Case Report: A 62-year-old male presented with a patch on the right neck with additional features of inflammation. Skin biopsies for hematoxylin and eosin examination, as well as for immunohistochemistry analysis were performed. Results: H&E staining demonstrated classic features of an inflamed seborrheic keratosis. Overexpression of LAT, COX-2, CD1a, and CD68 was noticed in the inflammatory infiltrate. A strong presence of CD1a was also seen in the epidermis suprajacent to the inflammation. Myeloid/histiocyte antigen was strongly expressed by the keratinocytes . Conclusion : A complex immune response seems to be involved in the pathophysiology of an inflamed seborrheic keratosis.

  12. Medical management of contact dermatitis.

    Science.gov (United States)

    Alexandroff, A B; Johnston, G A

    2009-10-01

    Allergic and irritant contact dermatitis are important dermatological problems. Although the frequencies of positive reactions to a number of allergens have decreased during last 30 years because of better avoidance (and at least in part due to improved legislation), contact allergy to other agents is rising. The medical treatment starts from a correct identification of triggers of contact dermatitis which could allow patients to reduce or avoid exposure to these agents in future. A good clinical history, examination and immunological tests including patch testing are of crucial importance at this stage. Further management includes emollients, topical and oral corticosteroids, topical calcineurin inhibitors, azathioprine and ciclosporin. Methotrexate and alitretinoin are recent additions to the armamentarium of dermatologists who manage contact dermatitis.

  13. Can atopic dermatitis be prevented?

    Science.gov (United States)

    Gómez-de la Fuente, E

    2015-05-01

    Atopic dermatitis has become a health problem in our setting due to its rising prevalence, impact on quality of life, associated costs, and role in the progression to other atopic diseases. Furthermore, atopic dermatitis has no definitive cure and therefore preventive measures are important. In this article, we review the latest advances in both primary prevention (reduction of the incidence of atopic dermatitis) and secondary prevention (reduction of associated morbidity and reduction of the atopic march). We analyze the different preventive strategies available, including modification of the immune system through microbial exposure, induction of immune tolerance through antigen exposure, and restoration of skin barrier function to halt the atopic march. Dermatologists need to be familiar with these strategies in order to apply them where necessary and to accurately inform patients and their relatives to prevent misguided or inappropriate actions. Copyright © 2014 Elsevier España, S.L.U. and AEDV. All rights reserved.

  14. Paederus dermatitis: A case series

    Directory of Open Access Journals (Sweden)

    Sahana Srihari

    2017-01-01

    Full Text Available Vorderman (1901 was the first to record blisters caused by beetles in medical literature. Blister beetle dermatitis is a cutaneous condition caused by the toxins released by blister beetles. The vesicant chemical in the body fluids of these insects causes an acute irritant contact dermatitis characterized by erythematovesicular lesions associated with burning sensation on exposed parts of the body. The aim of this study was to investigate the morphological patterns of blister beetle dermatitis. We conducted a 1-year (January–December 2014 prospective study of the clinical presentation of Paederus dermatitis noticed in urban and semiurban areas close to paddy fields in the Cauvery Basin, Mysuru, Karnataka. All patients with Paederus dermatitis attending the outpatient department of Department of Dermatology were recruited in the study with a total of 37 patients. Diagnosis was made on detailed history regarding onset of lesions, symptoms, as well as thorough clinical examination of the lesions. The peak time of presentation was June–September, the monsoon season in this part of India. The average duration of lesions at the time of presentation was 2–5 days. All patients had a history of burning and itchy sensation at night followed by full blown lesions the next morning, with the face, neck, and arms being the most common sites. Patients were predominantly males with the age range of 13–55 years. The most common presentations were linear erythematous plaques and erythematovesicles with a “burnt” appearance and a gray necrotic centre. “Kissing” lesions and periorbital involvement were seen in 5 and 6 patients, respectively. Species identification of the Paederus beetles was not done. Paederus dermatitis occurs in tropical regions. Awareness about the morphological patterns of the condition will prevent misdiagnosis. Simple preventive measures can be undertaken based on the behavioral pattern of this nocturnal beetle.

  15. [Atopic dermatitis and domestic animals].

    Science.gov (United States)

    Song, M

    2000-09-01

    Several arguments are raised attributing to aeroallergens an important role in atopic dermatitis. The aeroallergens that penetrate the epidermis could be fixed by IgE on the Langerhans cells and then induce a cellular mediator reaction comparable to that of allergic contact eczema. Patch tests have been developed to evaluate the role of aeroallergens (dust mites, animal dander, etc.). Preventive anti-dust mites measures in the home of atopic patients are recommended. Eviction of domestic animals (cat, dog, etc.) or avoidance measures for animal dander in the home can produce improvement in atopic dermatitis. Oral specific immunotherapy is being validated as a treatment for this disease.

  16. CONTACT DERMATITIS AMONG CONSTRUCTION WORKERS

    Directory of Open Access Journals (Sweden)

    Ida Ayu Diah Purnama Sari

    2013-02-01

    Full Text Available Contact dermatitis is a form of skin inflammation with spongiosis or intercellular edema of the epidermis due to the interaction of irritants and allergens. While occupational contact dermatitis is an inflammation of the skin due to exposure to irritants or allergens in the workplace. One of the jobs that have a high risk of the disease are construction workers. Although the disease is rarely-threatening but can cause high morbidity and suffering for workers, so it can affect the economy and quality of life of patients.

  17. Facial Injuries and Disorders

    Science.gov (United States)

    Face injuries and disorders can cause pain and affect how you look. In severe cases, they can affect sight, ... your nose, cheekbone and jaw, are common facial injuries. Certain diseases also lead to facial disorders. For ...

  18. Stoma dermatitis: prevalent but often overlooked.

    Science.gov (United States)

    Agarwal, Shilpa; Ehrlich, Alison

    2010-01-01

    Peristomal dermatoses commonly afflict the area around stoma openings in ostomy patients. These complications, however, are often unreported by patients and remain untreated for years, thus affecting maintenance and recovery from the surgery. These dermatoses can have chemical, mechanical, irritant, bacterial, immunologic, or disease-related etiologies. Examples of common forms of dermatitis that occur peristomally include fecal or urine irritant contact dermatitis, chronic papillomatous dermatitis, mechanical dermatitis, and allergic contact dermatitis. This article summarizes various skin irritations that can occur after an ostomy and also reviews previously published reports of peristomal allergic contact dermatitis. In addition, the clinical importance of identifying these dermatoses (most important, their effects on the patient's quality of life), risk factors for the skin irritations, the importance of patch testing, treatment of stoma dermatitis, and the importance of patient education and patient-doctor communication are also discussed.

  19. Facial Expression Analysis

    NARCIS (Netherlands)

    Pantic, Maja; Li, S.; Jain, A.

    2009-01-01

    Facial expression recognition is a process performed by humans or computers, which consists of: 1. Locating faces in the scene (e.g., in an image; this step is also referred to as face detection), 2. Extracting facial features from the detected face region (e.g., detecting the shape of facial compon

  20. Facial Expression Recognition

    NARCIS (Netherlands)

    Pantic, Maja; Li, S.; Jain, A.

    2009-01-01

    Facial expression recognition is a process performed by humans or computers, which consists of: 1. Locating faces in the scene (e.g., in an image; this step is also referred to as face detection), 2. Extracting facial features from the detected face region (e.g., detecting the shape of facial

  1. Facial paralysis in children.

    Science.gov (United States)

    Reddy, Sashank; Redett, Richard

    2015-04-01

    Facial paralysis can have devastating physical and psychosocial consequences. These are particularly severe in children in whom loss of emotional expressiveness can impair social development and integration. The etiologies of facial paralysis, prospects for spontaneous recovery, and functions requiring restoration differ in children as compared with adults. Here we review contemporary management of facial paralysis with a focus on special considerations for pediatric patients.

  2. Surgical-allogeneic facial reconstruction: facial transplants.

    Directory of Open Access Journals (Sweden)

    Marcelo Coelho Goiato

    2014-12-01

    Full Text Available Several factors including cancer, malformations and traumas may cause large facial mutilation. These functional and aesthetic deformities negatively affect the psychological perspectives and quality of life of the mutilated patient. Conventional treatments are prone to fail aesthetically and functionally. The recent introduction of the composite tissue allotransplantation (CTA, which uses transplanted facial tissues of healthy donors to recover the damaged or non-existent facial tissue of mutilated patients, resulted in greater clinical results. Therefore, the present study aims to conduct a literature review on the relevance and effectiveness of facial transplants in mutilated subjects. It was observed that the facial transplants recovered both the aesthetics and function of these patients and consequently improved their quality of life.

  3. Allergic and irritant contact dermatitis.

    Science.gov (United States)

    Nosbaum, Audrey; Vocanson, Marc; Rozieres, Aurore; Hennino, Anca; Nicolas, Jean-François

    2009-01-01

    Irritant and allergic contact dermatitis are common inflammatory skin diseases induced by repeated skin contact with low molecular weight chemicals, called xenobiotics or haptens. Although both diseases may have similar clinical presentations, they can be differentiated on pathophysiological grounds. Irritant contact dermatitis (ICD) is a non-specific inflammatory dermatitis brought about by activation of the innate immune system by the pro-inflammatory properties of chemicals. Allergic contact dermatitis (ACD) corresponds to a delayed-type hypersensitivity response with a skin inflammation mediated by hapten-specific T cells. Recent progress in the pathophysiology of chemical-induced skin inflammation has shown that ICD and ACD are closely associated and that the best way to prevent ACD is to develop strategies to avoid ICD. The immunological diagnosis of ICD or ACD requires investigation of the presence (ACD) or absence (ICD) of antigen-specific T cells. The detection of T cells can be performed in the skin (collected from ACD lesions or positive patch tests) and/or in the blood, particularly by using the enzyme-linked immunospot assay (ELISPOT). This method, recently developed in ACD to metals, offers a new biological tool enabling the immunobiological diagnosis of ACD.

  4. Clinicopathological study of exfoliative dermatitis

    Directory of Open Access Journals (Sweden)

    Sudho R

    2003-01-01

    Full Text Available A clinicopathological study of exfoliative dermatitis involving 25 fresh cases was carried out. Males were predominantly affected with a peak incidence between 21-30 years. Pruritus, shivering, erythema and scaling were the common clinical manifestations. Psoriasis and eczema were the most common aetiological factors and the histopathological findings were correlating with the same.

  5. Pyemotes ventricosus Dermatitis, Southeastern France

    OpenAIRE

    Del Giudice, Pascal; Blanc-Amrane, V?ronique; Bahadoran, Philippe; Caumes, Eric; Marty, Pierre; Lazar, Maril?na; Boissy, Christian; Desruelles, Fran?ois; Izri, Arezki; Ortonne, Jean-Paul; Counillon, Evelyne; Chosidow, Olivier; Delaunay, Pascal

    2008-01-01

    We investigated 42 patients who had unusual pruritic dermatitis associated with a specific clinical sign (comet sign) in 23 houses in southeastern France from May through September 2007. Pyemotes ventricosus, a parasite of the furniture beetle Anobium punctatum, was the cause of this condition.

  6. Pyemotes ventricosus dermatitis, southeastern France.

    Science.gov (United States)

    Del Giudice, Pascal; Blanc-Amrane, Véronique; Bahadoran, Philippe; Caumes, Eric; Marty, Pierre; Lazar, Mariléna; Boissy, Christian; Desruelles, François; Izri, Arezki; Ortonne, Jean-Paul; Counillon, Evelyne; Chosidow, Olivier; Delaunay, Pascal

    2008-11-01

    We investigated 42 patients who had unusual pruritic dermatitis associated with a specific clinical sign (comet sign) in 23 houses in southeastern France from May through September 2007. Pyemotes ventricosus, a parasite of the furniture beetle Anobium punctatum, was the cause of this condition.

  7. Diagnosis and management of contact dermatitis.

    Science.gov (United States)

    Usatine, Richard P; Riojas, Marcela

    2010-08-01

    Contact dermatitis is a common inflammatory skin condition characterized by erythematous and pruritic skin lesions that occur after contact with a foreign substance. There are two forms of contact dermatitis: irritant and allergic. Irritant contact dermatitis is caused by the non-immune-modulated irritation of the skin by a substance, leading to skin changes. Allergic contact dermatitis is a delayed hypersensitivity reaction in which a foreign substance comes into contact with the skin; skin changes occur after reexposure to the substance. The most common substances that cause contact dermatitis include poison ivy, nickel, and fragrances. Contact dermatitis usually leads to erythema and scaling with visible borders. Itching and discomfort may also occur. Acute cases may involve a dramatic flare with erythema, vesicles, and bullae; chronic cases may involve lichen with cracks and fissures. When a possible causative substance is known, the first step in confirming the diagnosis is determining whether the problem resolves with avoidance of the substance. Localized acute allergic contact dermatitis lesions are successfully treated with mid- or high-potency topical steroids, such as triamcinolone 0.1% or clobetasol 0.05%. If allergic contact dermatitis involves an extensive area of skin (greater than 20 percent), systemic steroid therapy is often required and offers relief within 12 to 24 hours. In patients with severe rhus dermatitis, oral prednisone should be tapered over two to three weeks because rapid discontinuation of steroids can cause rebound dermatitis. If treatment fails and the diagnosis or specific allergen remains unknown, patch testing should be performed.

  8. DERMATITIS KONTAK AKIBAT KERJA PADA PEKERJA GARMEN

    Directory of Open Access Journals (Sweden)

    I Made Stepanus Biondi Pramantara

    2014-01-01

    Full Text Available Occupational contact dermatitis is a dermatitis that occurs due to contact with thematerials that exist in the workplace, and this is not the case if the person does not work.In the textile workers, the incidence of occupational contact dermatitis ranks fourth ofall occupational skin diseases annually in Finland. Contact dermatitis is of two kinds,namely contact dermatitis (DKI arising through non-immunologic mechanisms andallergic contact dermatitis (DKAas a result of specific immunologic mechanism (slowtype hypersensitivity reaction (type IV. To assign a material cause of contactdermatitis required a careful history taking about, a complete medical history, physicalexamination and patch test and is also required investigation into the workplace toobserve the work and what materials are usually in contact with the patient when thepatient works. Some of the materials most commonly cause dermatitis due to work ingarment workers are resins, formaldehyde and dyes. Handling contact dermatitis can bedivided into non-pharmacological therapy and pharmacology. The best way toovercome work-related contact dermatitis is prevention by avoiding contact of thematerial causes. Long-term prognosis of occupational contact dermatitis is very bad,despite the best efforts of treatment and change the type of work has been done.

  9. A double-blind, placebo-controlled pilot study to estimate the efficacy and tolerability of a nonsteroidal cream for the treatment of cradle cap (seborrheic dermatitis).

    Science.gov (United States)

    David, Elmer; Tanuos, Hanan; Sullivan, Timothy; Yan, Albert; Kircik, Leon H

    2013-04-01

    This study was a multicenter, double-blind, placebo-controlled, parallel-group pilot study of efficacy and tolerability of a nonsteroidal cream (Promiseb® Topical Cream; Promius Pharma, LLC, Bridgewater, NJ) for treatment of cradle cap when applied topically twice daily for up to 14 days in 42 pediatric subjects. Both treatments were similarly effective in reducing disease severity, as measured by success with Investigator's Global Assessment scores at day 7 or end of treatment, with 96% of subjects achieving success in the nonsteroidal cream group and 92% of subjects achieving success in the placebo cream group. Both treatments resulted in significant reductions from baseline in terms of erythema, crusting, scaling, and oiliness (P<.05), with no significant difference between treatments. There was a significant difference (P=.03) between treatment groups for percent reduction in scaling at the end of treatment, with a 90% reduction in the nonsteroidal cream group compared with a 58% reduction in the placebo cream group. All subjects in both groups had an overall safety score of excellent, and there were no adverse events related to treatment for either group.

  10. Molecular diagnostics of psoriasis, atopic dermatitis, allergic contact dermatitis and irritant contact dermatitis.

    NARCIS (Netherlands)

    Kamsteeg, M.; Jansen, P.A.M.; Vlijmen-Willems, I.M.J.J. van; Erp, P.E.J. van; Rodijk-Olthuis, D.; Valk, P.G.M. van der; Feuth, T.; Zeeuwen, P.L.J.M.; Schalkwijk, J.

    2010-01-01

    BACKGROUND: Microarray studies on the epidermal transcriptome in psoriasis and atopic dermatitis (AD) have revealed genes with disease-specific expression in keratinocytes of lesional epidermis. These genes are possible candidates for disease-specific pathogenetic changes, but could also provide a t

  11. Milia after allergic contact dermatitis from poison ivy: two cases.

    Science.gov (United States)

    Berk, David R; Hurt, Mark A; Reese, Lester T; Wagner, Laura; Bayliss, Susan J

    2010-01-01

    Milia have rarely been reported as a complication of severe allergic contact dermatitis. To our knowledge, milia have not previously been associated with poison ivy dermatitis. We present two cases of milia after allergic contact dermatitis to poison ivy.

  12. Occupational allergic contact dermatitis from epoxy resin in a golf club repairman.

    Science.gov (United States)

    Isaksson, Marléne; Möller, Halvor; Pontén, Ann

    2008-01-01

    A golfer presented with facial and hand eczema. He had exacerbations of his hand eczema prior to golf tournaments. Being an authorized golf club repairman, he had been working with a two-part glue containing an epoxy resin (ER) based on diglycidyl ether of bisphenol A (DGEBA) and the hardener diethylenetriamine (DETA) for approximately 4 years before he developed any skin problems. He was patch-tested with the standard, which contains an ER based on DGEBA (DGEBA-R), epoxy (containing DETA), and rubber glove series and had positive reactions to DGEBA-R only. Other work materials (a latex glove, a golf glove made of leather, and part of the handle of his own golf club "as is" and in a methyl tert-butyl ether extract) were tested, with negative results. Allergic contact dermatitis from ER affects the skin by direct contact; the dermatitis is usually localized to the hands and forearms. If the face and eyelids are involved, the dermatitis may be due to exposure to airborne hardeners or reactive diluents, exposure to airborne dust from residual monomers, or ectopic allergic reactions. Our repairman had sandpapered an old glued surface, which may have led to possible airborne dust formation, thus explaining the facial eczema. Therefore, a worker with contact allergy to ER may continue working provided the skin is protected from contamination.

  13. The role of contact dermatitis in patients with atopic dermatitis.

    Science.gov (United States)

    Aquino, Marcella; Fonacier, Luz

    2014-01-01

    Because both atopic dermatitis (AD) and contact dermatitis (CD) are characterized by a similar morphologic appearance and similar distribution of skin involvement, the diagnosis of CD in AD has been difficult. Historically, it was thought that patients with AD were unable or less likely to develop CD due to various studies in which patients with AD stimulated with strong allergens failed to develop sensitization at rates similar to patients without AD. However, more recent evidence from the United States and Europe has shown that patients with AD have similar if not higher rates of positive patch test results to common contact allergens, including metals and fragrance, than those patients without AD. In this review, we highlight evidence for and against the role of contact allergy in patients with AD and seek to give clinically relevant management recommendations for the evaluation of CD in the patient with AD.

  14. Contact allergy in children with atopic dermatitis

    DEFF Research Database (Denmark)

    Simonsen, A B; Johansen, J D; Deleuran, M.

    2017-01-01

    The importance of contact allergy in children with atopic dermatitis is frequently debated. Previously, patients with atopic dermatitis were believed to have a reduced ability to produce a type IV immunological response. However, this belief has been challenged and authors have highlighted the risk...... of underestimating and overlooking allergic contact dermatitis in children with atopic dermatitis. Several studies have been published aiming to shed light on this important question but results are contradictory. To provide an overview of the existing knowledge, we systematically reviewed studies that report...... frequencies of positive patch test reactions in children with atopic dermatitis. We identified 436 manuscripts of which 31 met the inclusion criteria. Although the literature is conflicting, it is evident that contact allergy is a common problem in children with atopic dermatitis....

  15. Surgical treatment of facial paralysis.

    Science.gov (United States)

    Mehta, Ritvik P

    2009-03-01

    The management of facial paralysis is one of the most complex areas of reconstructive surgery. Given the wide variety of functional and cosmetic deficits in the facial paralysis patient, the reconstructive surgeon requires a thorough understanding of the surgical techniques available to treat this condition. This review article will focus on surgical management of facial paralysis and the treatment options available for acute facial paralysis (facial paralysis (3 weeks to 2 yr) and chronic facial paralysis (>2 yr). For acute facial paralysis, the main surgical therapies are facial nerve decompression and facial nerve repair. For facial paralysis of intermediate duration, nerve transfer procedures are appropriate. For chronic facial paralysis, treatment typically requires regional or free muscle transfer. Static techniques of facial reanimation can be used for acute, intermediate, or chronic facial paralysis as these techniques are often important adjuncts to the overall management strategy.

  16. Dermat - the dermoscopy management system

    Directory of Open Access Journals (Sweden)

    Grzegorz Surówka

    2013-04-01

    Full Text Available In order to recognize early symptoms of melanoma, the lethal cancer of the skin, our group is developing pattern recognition and machine learning tools that may help medical doctors in the melanoma diagnosis. Since in the machine learning approach data from diversified sources are required, in this article we present the Java-based Dermat 1.0 application, a medical software system for management of dermoscopy data and the patients follow-up documentation. The chief objective for this system is to integrate all the management activities (image acquisition, anamneses, medical documentation and annotations into a self-content optimal data base system. Such an integrated approach to digital dermoscopy and management of the patient data between the visits is crucial in comparing the results, storing/retrieving/transmitting dermoscopic images and making a proper and early diagnosis. The Dermat application is distributed among dermatological clinics and private practitioners in accordance to the 'tool-for-the-data' model.

  17. Contact dermatitis caused by preservatives.

    Science.gov (United States)

    Yim, Elizabeth; Baquerizo Nole, Katherine L; Tosti, Antonella

    2014-01-01

    Preservatives are biocidal chemicals added to food, cosmetics, and industrial products to prevent the growth of microorganisms. They are usually nontoxic and inexpensive and have a long shelf life. Unfortunately, they commonly cause contact dermatitis. This article reviews the most important classes of preservatives physicians are most likely to encounter in their daily practice, specifically isothiazolinones, formaldehyde and formaldehyde-releasers, iodopropynyl butylcarbamate, methyldibromoglutaronitrile, and parabens. For each preservative mentioned, the prevalence of sensitization, clinical presentation of contact dermatitis, patch testing concentrations, cross reactions, and related legislation will be discussed. Mandatory labeling of preservatives is required in some countries, but not required in others. Until policies are made, physicians and patients must be proactive in identifying potential sensitizers and removing their use. We hope that this article will serve as a guide for policy makers in creating legislation and future regulations on the use and concentration of certain preservatives in cosmetics and industrial products.

  18. Esomeprazole-induced photoallergic dermatitis

    Directory of Open Access Journals (Sweden)

    Shukla A

    2010-01-01

    Full Text Available There are no published case reports of esomeprazole-induced photoallergic dermatitis. We report here a 58-year-old lady with prior history of propylthiouracil and carbimazole-induced photoallergy, who presented with heartburn and dysphagia. She was diagnosed to have erosive esophagitis and was treated with esomeprazole, following which she developed photoallergic dermatitis. It improved on cessation of the drug and did not recur on subsequent treatment with ranitidine. Naranjo score for this adverse drug event was 8, thereby making it a probable adverse drug reaction. This reaction may be due to sulphur moiety, which is common to all these drugs. Physicians must be aware of this possible side-effect, especially in patients with prior history of photoallergy to other drugs.

  19. Allergic contact dermatitis from carmine.

    Science.gov (United States)

    Shaw, Daniel W

    2009-01-01

    A 28-year-old woman developed allergic contact dermatitis within 6 to 24 hours exclusively after using carmine-containing eyeshadows and lipsticks. She had both a positive patch test result and a positive antecubital repeated open application test result with carmine 2.5% in petrolatum. Thirty other patients had negative patch test results. Carmine is a widely used pigment derived from gravid cochineal insects. Carminic acid is the source of its color. Only two previous publications describing allergic contact dermatitis from carmine could be found. The ingredient in carmine causing these delayed hypersensitivity reactions has not been studied. In contrast, there are numerous reports of immediate hypersensitivity reactions from carmine, mostly from its use in foods and beverages but also from cosmetics and pharmaceuticals. These are immunoglobulin E-mediated reactions directed against cochineal proteins.

  20. Japanese guidelines for atopic dermatitis 2017

    Directory of Open Access Journals (Sweden)

    Ichiro Katayama

    2017-04-01

    The basics of treatment discussed in this guideline are based on the “Guidelines for the Treatment of Atopic Dermatitis 2008” prepared by the Health and Labour Sciences Research and the “Guidelines for the Management of Atopic Dermatitis 2015 (ADGL2015” prepared by the Atopic Dermatitis Guidelines Advisory Committee, Japanese Society of Allergology in principle. The guidelines for the treatment of atopic dermatitis are summarized in the “Japanese Guideline for the Diagnosis and Treatment of Allergic Disease 2016” together with those for other allergic diseases.

  1. Allergic contact dermatitis: Patient management and education.

    Science.gov (United States)

    Mowad, Christen M; Anderson, Bryan; Scheinman, Pamela; Pootongkam, Suwimon; Nedorost, Susan; Brod, Bruce

    2016-06-01

    Allergic contact dermatitis is a common diagnosis resulting from exposure to a chemical or chemicals in a patient's personal care products, home, or work environment. Once patch testing has been performed, the education and management process begins. After the causative allergens have been identified, patient education is critical to the proper treatment and management of the patient. This must occur if the dermatitis is to resolve. Detailed education is imperative, and several resources are highlighted. Photoallergic contact dermatitis and occupational contact dermatitis are other considerations a clinician must keep in mind. Copyright © 2015 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.

  2. Allergic contact dermatitis caused by dorzolamide eyedrops

    Directory of Open Access Journals (Sweden)

    Lee SJ

    2015-04-01

    Full Text Available Seung-Jun Lee, Moosang KimDepartment of Ophthalmology, School of Medicine, Kangwon National University, Chuncheon, KoreaAbstract: The side effects of topical dorzolamide hydrochloride, such as conjunctivitis, eyelid edema, and eye lid irritation, are well known. However, allergic contact dermatitis due to dorzolamide is rare, although the product has been commonly used worldwide in patients with glaucoma. To the best of our knowledge, this is the first report of allergic contact dermatitis caused by topical dorzolamide hydrochloride in Korea. Herein we report a case of allergic contact dermatitis due to topical dorzolamide eyedrops.Keywords: allergic contact dermatitis, dorzolamide, side effects

  3. Japanese Guideline for Atopic Dermatitis 2014

    Directory of Open Access Journals (Sweden)

    Ichiro Katayama

    2014-01-01

    The basics of treatment discussed in this guideline are based on the "Guidelines for the Treatment of Atopic Dermatitis 2008" prepared by the Health and Labour Sciences Research and the "Guidelines for the Management of Atopic Dermatitis 2012 (ADGL2012" prepared by the Atopic Dermatitis Guidelines Advisory Committee, Japanese Society of Allergology in principle. The guidelines for the treatment of atopic dermatitis are summarized in the "Japanese Guideline for the Diagnosis and Treatment of Allergic Disease 2013" together with those for other allergic diseases.

  4. Identification and treatment of poison ivy dermatitis.

    Science.gov (United States)

    Briant, D; Brouder, G

    1983-01-01

    Poison ivy dermatitis is an acute self-limiting problem of two or three weeks' duration that can cause significant discomfort. Poison ivy, poison oak and poison sumac cause more cases of allergic contact dermatitis than all the other contact allergens combined. Treatment of poison ivy dermatitis depends on the severity of the reaction. The nurse practitioner can manage the majority of poison ivy cases. However, if there is systemic involvement, a physician consultation is necessary. The patient can best be assisted by assessing the severity of the dermatitis, prescribing an appropriate supportive therapy and teaching preventive measures.

  5. Contemporary facial reanimation.

    Science.gov (United States)

    Bhama, Prabhat K; Hadlock, Tessa A

    2014-04-01

    The facial nerve is the most commonly paralyzed nerve in the human body. Facial paralysis affects aesthetic appearance, and it has a profound effect on function and quality of life. Management of patients with facial paralysis requires a multidisciplinary approach, including otolaryngologists, plastic surgeons, ophthalmologists, and physical therapists. Regardless of etiology, patients with facial paralysis should be evaluated systematically, with initial efforts focused upon establishing proper diagnosis. Management should proceed with attention to facial zones, including the brow and periocular region, the midface and oral commissure, the lower lip and chin, and the neck. To effectively compare contemporary facial reanimation strategies, it is essential to employ objective intake assessment methods, and standard reassessment schemas during the entire management period.

  6. Dermat - the dermoscopy management system

    OpenAIRE

    Grzegorz Surówka; Paweł Janik; Maciej Ogorzałek; Piotr Kanas

    2013-01-01

    In order to recognize early symptoms of melanoma, the lethal cancer of the skin, our group is developing pattern recognition and machine learning tools that may help medical doctors in the melanoma diagnosis. Since in the machine learning approach data from diversified sources are required, in this article we present the Java-based Dermat 1.0 application, a medical software system for management of dermoscopy data and the patients follow-up documentation. The chief objective for this system i...

  7. Therapeutic perspectives in atopic dermatitis.

    Science.gov (United States)

    Misery, Laurent

    2011-12-01

    Therapy of atopic dermatitis should comprise emollients, topical glucocorticosteroids, or calcineurin inhibitors, phototherapies, immunosuppressants like cyclosporin A, and other treatments. All these treatments should be improved, thanks to research. But new therapeutic perspectives should be given by topical anti-inflammatory substances, selective glucocorticoid receptor agonists, probiotics, interferon γ, TNFα inhibitors, inhibition of T cells or B cells, inhibition of IgE binding, and many other possibilities.

  8. Histopathological spectrum of Psoriasiform dermatitis

    Directory of Open Access Journals (Sweden)

    PL Jayalakshmy

    2016-09-01

    Full Text Available Background: Psoriasiform dermatitis is a frequently encountered terminology in a wide variety of inflammatory dermatoses. It often poses challenges to both dermatologists and pathologists alike. Clinical features when considered alone may not be reliable, as they vary with both disease duration and treatment. On the contrary, histopathological material constitutes definite hard evidence, which can be preserved and will continue to be available for future review. The objective of the study is to study the histopathological findings in Psoriasiform dermatitis.Materials and Methods: This is a retrospective study in a tertiary care centre in Kerala, South India. All cases diagnosed as Psoriasis or mentioned as one of the differential diagnosis were included. The material included 66 skin biopsies. Patients with a previous diagnosis of the same were excluded from the study.Results: The lesions comprised 9% of the total number of skin biopsies. The age distribution pattern revealed that the highest percentage was in the 41-60 year age group (50% with a male preponderance of 65%. Psoriasis was the most common lesion (60.60% and Lichen simplex chronicus was the second most common lesion (10.60 %, encountered in the study.Conclusion: Some of the histopathological features are specific and characteristic for each entity like Psoriasis, Pityriasis rubra pilaris, Pityriasis rosea and Inflammatory linear verrucous epidermal nevus whereas some overlap in lesions like Prurigo nodularis, Lichen simplex chronicus and Allergic contact dermatitis. Hence, combination of proper clinical observation and histopathological study will give a conclusive diagnosis.

  9. Facial Reconstruction and Rehabilitation.

    Science.gov (United States)

    Guntinas-Lichius, Orlando; Genther, Dane J; Byrne, Patrick J

    2016-01-01

    Extracranial infiltration of the facial nerve by salivary gland tumors is the most frequent cause of facial palsy secondary to malignancy. Nevertheless, facial palsy related to salivary gland cancer is uncommon. Therefore, reconstructive facial reanimation surgery is not a routine undertaking for most head and neck surgeons. The primary aims of facial reanimation are to restore tone, symmetry, and movement to the paralyzed face. Such restoration should improve the patient's objective motor function and subjective quality of life. The surgical procedures for facial reanimation rely heavily on long-established techniques, but many advances and improvements have been made in recent years. In the past, published experiences on strategies for optimizing functional outcomes in facial paralysis patients were primarily based on small case series and described a wide variety of surgical techniques. However, in the recent years, larger series have been published from high-volume centers with significant and specialized experience in surgical and nonsurgical reanimation of the paralyzed face that have informed modern treatment. This chapter reviews the most important diagnostic methods used for the evaluation of facial paralysis to optimize the planning of each individual's treatment and discusses surgical and nonsurgical techniques for facial rehabilitation based on the contemporary literature.

  10. [Facial tics and spasms].

    Science.gov (United States)

    Potgieser, Adriaan R E; van Dijk, J Marc C; Elting, Jan Willem J; de Koning-Tijssen, Marina A J

    2014-01-01

    Facial tics and spasms are socially incapacitating, but effective treatment is often available. The clinical picture is sufficient for distinguishing between the different diseases that cause this affliction.We describe three cases of patients with facial tics or spasms: one case of tics, which are familiar to many physicians; one case of blepharospasms; and one case of hemifacial spasms. We discuss the differential diagnosis and the treatment possibilities for facial tics and spasms. Early diagnosis and treatment is important, because of the associated social incapacitation. Botulin toxin should be considered as a treatment option for facial tics and a curative neurosurgical intervention should be considered for hemifacial spasms.

  11. History of facial pain diagnosis

    DEFF Research Database (Denmark)

    Zakrzewska, Joanna M; Jensen, Troels S

    2017-01-01

    Premise Facial pain refers to a heterogeneous group of clinically and etiologically different conditions with the common clinical feature of pain in the facial area. Among these conditions, trigeminal neuralgia (TN), persistent idiopathic facial pain, temporomandibular joint pain, and trigeminal...

  12. Dermatitis herpetiformis and neurological dysfunction.

    Science.gov (United States)

    Wills, A J; Turner, B; Lock, R J; Johnston, S L; Unsworth, D J; Fry, L

    2002-02-01

    Dermatitis herpetiformis and coeliac disease are gluten sensitive diseases, which have common immunopathological and genetic mechanisms. Neuropsychiatric complications have been reported in up to 26% of patients with coeliac disease. This is probably an overestimate, because of the chance associations with some common neurological conditions such as epilepsy. The pathogenesis is speculative but it has been postulated that gluten is neurotoxic possibly via immune mechanisms. The frequency of neurological dysfunction in patients with dermatitis herpetiformis has not been characterised. Patients with dermatitis herpetiformis might be expected to be particularly susceptible to neuronal damage as some continue to consume gluten when their dermatological symptoms are controlled by dapsone. Thirty five patients were recruited with dermatitis herpetiformis from dermatology clinics at St Mary's Hospital, London and Queen's Medical Centre, Nottingham and investigated for evidence of neurological abnormality. All patients underwent a full neurological examination and were asked about their neurological and general medical history by means of a structured questionnaire. Serum samples were taken and screened for the presence of anti-neuronal antibodies (anti-Hu and Yo) as well as anti-gliadin (IgA and G) anti-endomysial (IgA), and anti-tissue transglutaminase (IgA) antibodies. Neurophysiological tests were carried out where appropriate. Only two patients were identified with unexplained neurological abnormalities (one essential tremor, and one chorea). Two other patients had a history of migraine. The patient with chorea also had borderline/equivocally positive anti-Hu antibodies by immunofluorescence assay. All other samples were negative for anti-neuronal antibodies. Fifteen patients were positive for anti-gliadin antibodies (IgA and/or IgG), four for anti-endomysial antibodies (monkey oesophagus or umbilical cord), and six for anti-tissue transglutaminase antibodies. The

  13. Facial asymmetry: a case report of localized linear scleroderma patient with muscular strain and spasm.

    Science.gov (United States)

    Kim, Jae-Hyung; Lee, Suck-Chul; Kim, Chul-Hoon; Kim, Bok-Joo

    2015-12-01

    Facial asymmetry is found in patients with or without cosmetic facial alterations. Some patients have facial asymmetry that manifests underlying skeletal problems, while others have only limited soft-tissue facial asymmetry. Orthognathic surgery brings about a dermatic change, as soft tissue covers underlying bones. Limited soft-tissue asymmetry, meanwhile, is difficult to correct. The treatment modalities for the creation or restoration of an esthetically pleasing appearance were autogenous fat grafts, cartilage graft, and silicon injections. A young female patient had right-side facial asymmetry. The clinical assessment involved visual inspection of the face and palpation to differentiate soft tissue and bone. Although the extra-oral examination found facial asymmetry with skin atrophy, the radiographic findings revealed no mandibular atrophy or deviation. She was diagnosed as localized scleroderma with muscle spasm. In conclusion, facial asymmetry patients with skeletal asymmetry can be esthetically satisfied by orthognathic surgery; however, facial atrophy patients with skin or subdermal tissue contraction need treatment by cosmetic dermatological surgery and orthodontic correction.

  14. Association between atopic dermatitis and contact sensitization

    DEFF Research Database (Denmark)

    Hamann, Carsten R; Hamann, Dathan; Egeberg, Alexander

    2017-01-01

    BACKGROUND: It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower...... contact dermatitis is suspected....

  15. Occupational poison ivy and oak dermatitis.

    Science.gov (United States)

    Epstein, W L

    1994-07-01

    Among the growing and diverse groups of outdoor and environmental workers, poison ivy and poison oak continue to be the major cause of occupational contact dermatitis. This article reviews the practical and theoretic means to prevent poison ivy and poison oak dermatitis in workers occupationally exposed to these weeds.

  16. Occupational allergic contact dermatitis to nitromethane.

    Science.gov (United States)

    Webb, Kelli G; Fowler, Joseph F

    2002-12-01

    Nitromethane has wide industrial and commercial application as a polar solvent for adhesives and acrylics as well as explosive fuel. Allergic contact dermatitis to this chemical has not been described previously. The authors documented allergic contact hand dermatitis in 4 coworkers who similarly handled an adhesive solvent containing nitromethane. All 4 cases were confirmed by patch testing and resolved after allergen avoidance.

  17. Facial expression and sarcasm.

    Science.gov (United States)

    Rockwell, P

    2001-08-01

    This study examined facial expression in the presentation of sarcasm. 60 responses (sarcastic responses = 30, nonsarcastic responses = 30) from 40 different speakers were coded by two trained coders. Expressions in three facial areas--eyebrow, eyes, and mouth--were evaluated. Only movement in the mouth area significantly differentiated ratings of sarcasm from nonsarcasm.

  18. Holistic facial expression classification

    Science.gov (United States)

    Ghent, John; McDonald, J.

    2005-06-01

    This paper details a procedure for classifying facial expressions. This is a growing and relatively new type of problem within computer vision. One of the fundamental problems when classifying facial expressions in previous approaches is the lack of a consistent method of measuring expression. This paper solves this problem by the computation of the Facial Expression Shape Model (FESM). This statistical model of facial expression is based on an anatomical analysis of facial expression called the Facial Action Coding System (FACS). We use the term Action Unit (AU) to describe a movement of one or more muscles of the face and all expressions can be described using the AU's described by FACS. The shape model is calculated by marking the face with 122 landmark points. We use Principal Component Analysis (PCA) to analyse how the landmark points move with respect to each other and to lower the dimensionality of the problem. Using the FESM in conjunction with Support Vector Machines (SVM) we classify facial expressions. SVMs are a powerful machine learning technique based on optimisation theory. This project is largely concerned with statistical models, machine learning techniques and psychological tools used in the classification of facial expression. This holistic approach to expression classification provides a means for a level of interaction with a computer that is a significant step forward in human-computer interaction.

  19. Facial talon cusps.

    LENUS (Irish Health Repository)

    McNamara, T

    1997-12-01

    This is a report of two patients with isolated facial talon cusps. One occurred on a permanent mandibular central incisor; the other on a permanent maxillary canine. The locations of these talon cusps suggests that the definition of a talon cusp include teeth in addition to the incisor group and be extended to include the facial aspect of teeth.

  20. Contact Dermatitis for the Practicing Allergist.

    Science.gov (United States)

    Bernstein, David I

    2015-01-01

    This article provides an overview of important practice recommendations from the recently updated Contact Dermatitis Practice Parameter. This updated parameter provides essential recommendations pertaining to clinical history, physical examination, and patch testing evaluation of patients suspected of allergic contact dermatitis. In addition to providing guidance for performing and interpreting closed patch testing, the updated parameter provides concrete recommendations for assessing metal hypersensitivity in patients receiving prosthetic devices, for evaluating workers with occupational contact dermatitis, and also for addressing allergic contact dermatitis in children. Finally, the document provides practical recommendations useful for educating patients regarding avoidance of exposure to known contact sensitizers in the home and at work. The Contact Dermatitis Parameter is designed as a practical, evidence-based clinical tool to be used by allergists and dermatologists who routinely are called upon to evaluate patients with skin disorders.

  1. Skin absorption through atopic dermatitis skin

    DEFF Research Database (Denmark)

    Halling-Overgaard, A-S; Kezic, S; Jakasa, I

    2017-01-01

    Patients with atopic dermatitis have skin barrier impairment in both lesional and non-lesional skin. They are typically exposed to emollients daily and topical anti-inflammatory medicaments intermittently, hereby increasing the risk of developing contact allergy and systemic exposed to chemicals...... ingredients found in these topical preparations. We systematically searched for studies that investigated skin absorption of various penetrants, including medicaments, in atopic dermatitis patients, but also animals with experimentally induced dermatitis. We identified 40 articles, i.e. 11 human studies...... examining model penetrants, 26 human studies examining atopic dermatitis drugs and 3 animal studies. We conclude that atopic dermatitis patients have nearly two-fold increased skin absorption when compared to healthy controls. There is a need for well-designed epidemiological and dermato...

  2. OCCUPATIONAL CONTACT DERMATITIS IN HAIRDRESSERS

    Directory of Open Access Journals (Sweden)

    Komang Ayu Kristiana Dewi K

    2013-07-01

    Full Text Available Occupational skin disease is a skin disease caused or aggravated by work. Occupational skin disease experienced by most hairdressers are contact dermatitis, both irritant and allergic. Some examples of materials that can cause contact dermatitis in hairdressers are nickel, formaldehyde, ammonium thioglycolate, and p-phenylenediaminz. Diagnosis of contact dermatitis in hairdressers enforced through anamnesa, physical examination, and additional tests that are relevant include patch test. The most important treatment is to avoid exposure to irritants and eliminate factors that aggravate. Where appropriate, to address the inflammation can be given topical corticosteroids, such as hydrocortisone. Normal 0 false false false EN-US X-NONE X-NONE /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  3. Spontaneous Facial Mimicry in Response to Dynamic Facial Expressions

    Science.gov (United States)

    Sato, Wataru; Yoshikawa, Sakiko

    2007-01-01

    Based on previous neuroscientific evidence indicating activation of the mirror neuron system in response to dynamic facial actions, we hypothesized that facial mimicry would occur while subjects viewed dynamic facial expressions. To test this hypothesis, dynamic/static facial expressions of anger/happiness were presented using computer-morphing…

  4. Sound-induced facial synkinesis following facial nerve paralysis

    NARCIS (Netherlands)

    Ma, Ming-San; van der Hoeven, Johannes H.; Nicolai, Jean-Philippe A.; Meek, Marcel F.

    2009-01-01

    Facial synkinesis (or synkinesia) (FS) occurs frequently after paresis or paralysis of the facial nerve and is in most cases due to aberrant regeneration of (branches of) the facial nerve. Patients suffer from inappropriate and involuntary synchronous facial muscle contractions. Here we describe two

  5. Dermatitis artefacta: Three case reports

    Directory of Open Access Journals (Sweden)

    Walia N

    2006-01-01

    Full Text Available Three cases of dermatitis artefacta are reported for their varied presentation, diagnostic indicators and complex management. A 21-year-old soldier had multiple painful erosions on dorsum of both forearms of three weeks duration normal with inbetween skin. By occlusive bandaging dressing lesions healed without recurrence. A 28-year-old mechanic had recurrent blisters with non healing wounds on the right knee without surrounding inflammation. Histopathology was nonspecific. A young soldier had multiple asymphomatic nodular lesion in linear distribution on right forearm of two years induration. Biopsy showed features of scar. Psychiatric evaluation and follow-up was essential in all cases.

  6. [Asteatotic dermatitis: etiology and pathogenesis].

    Science.gov (United States)

    Zhou, Li-juan; Lyu, Zhong-fa

    2015-07-01

    Asteatotic dermatitis (AsD) is a common skin disease characterized by dry skin, itching, erythema, peeling and other skin lesions. It results from the damage in cutaneous barrier related to age, seasonal climate and bathing habits, and presents dysfunction of sebaceous, sweat glands and the increase of transepidermal water loss. The pathogenesis of AsD is not clear. Previous studies mainly focused on the relationship between skin barrier damage and bathing habits, age or gender. Recently, more studies focus on its relationship with other systematic diseases and drugs. This paper reviews etiology and pathogenesis of AsD to provide new ideas for the diagnosis and treatment of AsD.

  7. Contact dermatitis due to minoxidil

    Directory of Open Access Journals (Sweden)

    Pasricha J

    1991-01-01

    Full Text Available A 25-year old girl having androgenetic alopecia developed itching and erythema on the scalp one month after she started applying a commercial preparation containing 2% minoxidil. The dermatitis disappeared on discontinuing minoxidil but recurred when she applied minoxidil again after a gap of 1 month. Patch tests revealed a papulo-vesicular reaction with the commercial minoxidil lotion and also with a minoxidil tablet powdered and made into a paste with distilled water. Patch tests with ethyl alcohol were negative.

  8. Bibliometrics, dermatology and contact dermatitis.

    Science.gov (United States)

    Smith, Derek R

    2008-09-01

    Although the fields of bibliometrics and citation analysis have existed for many years, relatively few studies have specifically focused on the dermatological literature. This article reviews citation-based research in the dermatology journals, with a particular interest in manuscripts that have included Contact Dermatitis as part of their analysis. Overall, it can be seen that the rise of bibliometrics during the mid-20th century and its subsequent application to dermatology has provided an interesting insight into the progression of research within our discipline. Further investigation of citation trends and top-cited papers in skin research periodicals would certainly help complement the current body of knowledge.

  9. Allergic contact dermatitis and cosmetics.

    Science.gov (United States)

    Watkins, Shannon; Zippin, Jonathan

    2012-10-01

    Contact dermatitis is a common dermatologic condition that can result from exposure to allergens at home or at work. Cosmetics represent a large diverse group of products that Americans apply to their skin to treat disease or enhance beauty. With increased use of cosmetics, the rate of sensitization to many allergenic components has increased. We review the more common allergens present in cosmetics as well as the types of cosmetics that are known to contain them. With proper education and patch testing, dermatologists will be able to identify contact allergies to cosmetic ingredients and help patients avoid the offending products.

  10. Live facial feature extraction

    Institute of Scientific and Technical Information of China (English)

    ZHAO JieYu

    2008-01-01

    Precise facial feature extraction is essential to the high-level face recognition and expression analysis. This paper presents a novel method for the real-time geomet-ric facial feature extraction from live video. In this paper, the input image is viewed as a weighted graph. The segmentation of the pixels corresponding to the edges of facial components of the mouth, eyes, brows, and nose is implemented by means of random walks on the weighted graph. The graph has an 8-connected lattice structure and the weight value associated with each edge reflects the likelihood that a random walker will cross that edge. The random walks simulate an anisot-ropic diffusion process that filters out the noise while preserving the facial expres-sion pixels. The seeds for the segmentation are obtained from a color and motion detector. The segmented facial pixels are represented with linked lists in the origi-nal geometric form and grouped into different parts corresponding to facial com-ponents. For the convenience of implementing high-level vision, the geometric description of facial component pixels is further decomposed into shape and reg-istration information. Shape is defined as the geometric information that is invari-ant under the registration transformation, such as translation, rotation, and iso-tropic scale. Statistical shape analysis is carried out to capture global facial fea-tures where the Procrustes shape distance measure is adopted. A Bayesian ap-proach is used to incorporate high-level prior knowledge of face structure. Ex-perimental results show that the proposed method is capable of real-time extraction of precise geometric facial features from live video. The feature extraction is robust against the illumination changes, scale variation, head rotations, and hand inter-ference.

  11. PCA facial expression recognition

    Science.gov (United States)

    El-Hori, Inas H.; El-Momen, Zahraa K.; Ganoun, Ali

    2013-12-01

    This paper explores and compares techniques for automatically recognizing facial actions in sequences of images. The comparative study of Facial Expression Recognition (FER) techniques namely Principal Component's analysis (PCA) and PCA with Gabor filters (GF) is done. The objective of this research is to show that PCA with Gabor filters is superior to the first technique in terms of recognition rate. To test and evaluates their performance, experiments are performed using real database by both techniques. The universally accepted five principal emotions to be recognized are: Happy, Sad, Disgust and Angry along with Neutral. The recognition rates are obtained on all the facial expressions.

  12. Cow cleanliness and digital dermatitis

    DEFF Research Database (Denmark)

    Nielsen, Bodil Højlund

    2012-01-01

    Digital dermatitis (DD) is an infectious cattle disease presumably caused by Treponema spp. It results in painful, ulcerative lesions in the skin of the distal extremities and can be associated with lameness in affected animals. Today, DD is a very prevalent disease in the dairy industry and ther......Digital dermatitis (DD) is an infectious cattle disease presumably caused by Treponema spp. It results in painful, ulcerative lesions in the skin of the distal extremities and can be associated with lameness in affected animals. Today, DD is a very prevalent disease in the dairy industry...... cleanliness. More knowledge on these aspects will increase our understanding of the disease epidemiology and is essential to improve the success of controlling DD at the herd level. Therefore, the objectives of the present PhD thesis were 1) To investigate the relationship between cow leg cleanliness and DD......; 2) To identify potential risk factors for poor cow leg cleanliness; and 3) To gain more knowledge about potential means of controlling DD. Data was obtained from three studies conducted in commercial Danish dairy herds and the results are presented in four scientific papers. In the first study, cow...

  13. Cow cleanliness and digital dermatitis

    DEFF Research Database (Denmark)

    Nielsen, Bodil Højlund

    2012-01-01

    Digital dermatitis (DD) is an infectious cattle disease presumably caused by Treponema spp. It results in painful, ulcerative lesions in the skin of the distal extremities and can be associated with lameness in affected animals. Today, DD is a very prevalent disease in the dairy industry and ther......Digital dermatitis (DD) is an infectious cattle disease presumably caused by Treponema spp. It results in painful, ulcerative lesions in the skin of the distal extremities and can be associated with lameness in affected animals. Today, DD is a very prevalent disease in the dairy industry...... and therefore has a major impact on economics and cow welfare. Moist and unhygienic conditions in the cows’ surroundings are considered as important risk factors for DD partly because this can disturb the skin barrier and make the animals more susceptible to infection and partly because the environment might...... act as an infection reservoir. Measures of cow leg cleanliness can be used as a proxy of the hygienic conditions on the floors. Nonetheless, only few studies have used direct measures of cleanliness in association with the risk of DD. Also, little is known about what factors can influence the cow leg...

  14. Surgical Treatment of Facial Paralysis

    OpenAIRE

    Mehta, Ritvik P.

    2009-01-01

    The management of facial paralysis is one of the most complex areas of reconstructive surgery. Given the wide variety of functional and cosmetic deficits in the facial paralysis patient, the reconstructive surgeon requires a thorough understanding of the surgical techniques available to treat this condition. This review article will focus on surgical management of facial paralysis and the treatment options available for acute facial paralysis (2 yr). For acute facial paralysis, the main surgi...

  15. Toxicodendron dermatitis: poison ivy, oak, and sumac.

    Science.gov (United States)

    Gladman, Aaron C

    2006-01-01

    Allergic contact dermatitis caused by the Toxicodendron (formerly Rhus) species-poison ivy, poison oak, and poison sumac-affects millions of North Americans every year. In certain outdoor occupations, for example, agriculture and forestry, as well as among many outdoor enthusiasts, Toxicodendron dermatitis presents a significant hazard. This review considers the epidemiology, identification, immunochemistry, pathophysiology, clinical features, treatment, and prevention of this common dermatologic problem. Recent research in prevention is emphasized, and resources to help in the identification of plants are provided in the bibliography. The literature was searched using a MEDLINE query for "Toxicodendron dermatitis", and the identified article bibliographies were searched as well.

  16. [Epoxy resin systems and contact dermatitis].

    Science.gov (United States)

    Pietranek, Jolanta Eliza

    2007-01-01

    Contact dermatitis is the major chronic skin disease that represents a global health problem. Its prevalence has been significant increasing in the latest decades. Contact dermatitis substantially alters the social life of patients and affects their work productivity. Epoxy resin systems are a frequent cause of occupational allergic contact dermatitis. Epoxy resins have an extremely wide range of commercial applications. Epoxy resin systems include combinations of epoxy monomers, hardeners, reactive diluents, and/or a vast array of other additives. In occupational settings, sensitization occurs not only to resins, but also to hardeners and reactive diluents. In this article adverse effects of epoxy resin systems are discussed.

  17. [Dermatitis from contact with Agave americana].

    Science.gov (United States)

    Golan, H; Landau, M; Goldberg, I; Brenner, S

    2000-10-01

    Various plants induce dermatitis in man. There have been only a few published cases of contact dermatitis caused by Agave americana (AA). We report intentional exposure to AA in a soldier seeking sick leave, and review our previously reported cases. Treatment with oral antihistamines and topical saline compresses resulted in subsidence of the systemic symptoms within 24 h and regression of cutaneous manifestations in 7-10 days. Physicians should be alert to the possibility of self-inflicted contact dermatitis induced by exposure to plants, especially to A. americana. Systemic signs may accompany the cutaneous lesions.

  18. Persistent facial pain conditions

    DEFF Research Database (Denmark)

    Forssell, Heli; Alstergren, Per; Bakke, Merete

    2016-01-01

    , clinical features, consequences, central and peripheral mechanisms, diagnostic criteria (DC/TMD), and principles of management. For each of the neuropathic facial pain entities, the definitions, prevalence, clinical features, and diagnostics are described. The current understanding of the pathophysiology......Persistent facial pains, especially temporomandibular disorders (TMD), are common conditions. As dentists are responsible for the treatment of most of these disorders, up-to date knowledge on the latest advances in the field is essential for successful diagnosis and management. The review covers...... TMD, and different neuropathic or putative neuropathic facial pains such as persistent idiopathic facial pain and atypical odontalgia, trigeminal neuralgia and painful posttraumatic trigeminal neuropathy. The article presents an overview of TMD pain as a biopsychosocial condition, its prevalence...

  19. Persistent facial pain conditions

    DEFF Research Database (Denmark)

    Forssell, Heli; Alstergren, Per; Bakke, Merete

    2016-01-01

    TMD, and different neuropathic or putative neuropathic facial pains such as persistent idiopathic facial pain and atypical odontalgia, trigeminal neuralgia and painful posttraumatic trigeminal neuropathy. The article presents an overview of TMD pain as a biopsychosocial condition, its prevalence......Persistent facial pains, especially temporomandibular disorders (TMD), are common conditions. As dentists are responsible for the treatment of most of these disorders, up-to date knowledge on the latest advances in the field is essential for successful diagnosis and management. The review covers......, clinical features, consequences, central and peripheral mechanisms, diagnostic criteria (DC/TMD), and principles of management. For each of the neuropathic facial pain entities, the definitions, prevalence, clinical features, and diagnostics are described. The current understanding of the pathophysiology...

  20. Persistent facial pain conditions

    DEFF Research Database (Denmark)

    Forssell, Heli; Alstergren, Per; Bakke, Merete;

    2016-01-01

    , clinical features, consequences, central and peripheral mechanisms, diagnostic criteria (DC/TMD), and principles of management. For each of the neuropathic facial pain entities, the definitions, prevalence, clinical features, and diagnostics are described. The current understanding of the pathophysiology...

  1. Management of facial blushing

    DEFF Research Database (Denmark)

    Licht, Peter B; Pilegaard, Hans K

    2008-01-01

    people. Side effects are frequent, but most patients are satisfied with the operation. In the short term, the key to success in sympathetic surgery for facial blushing lies in a meticulous and critical patient selection and in ensuring that the patient is thoroughly informed about the high risk of side...... effects. In the long term, the key to success in sympathetic surgery for facial blushing lies in more quality research comparing surgical, pharmacologic, and psychotherapeutic treatments....

  2. Simultaneous facial feature tracking and facial expression recognition.

    Science.gov (United States)

    Li, Yongqiang; Wang, Shangfei; Zhao, Yongping; Ji, Qiang

    2013-07-01

    The tracking and recognition of facial activities from images or videos have attracted great attention in computer vision field. Facial activities are characterized by three levels. First, in the bottom level, facial feature points around each facial component, i.e., eyebrow, mouth, etc., capture the detailed face shape information. Second, in the middle level, facial action units, defined in the facial action coding system, represent the contraction of a specific set of facial muscles, i.e., lid tightener, eyebrow raiser, etc. Finally, in the top level, six prototypical facial expressions represent the global facial muscle movement and are commonly used to describe the human emotion states. In contrast to the mainstream approaches, which usually only focus on one or two levels of facial activities, and track (or recognize) them separately, this paper introduces a unified probabilistic framework based on the dynamic Bayesian network to simultaneously and coherently represent the facial evolvement in different levels, their interactions and their observations. Advanced machine learning methods are introduced to learn the model based on both training data and subjective prior knowledge. Given the model and the measurements of facial motions, all three levels of facial activities are simultaneously recognized through a probabilistic inference. Extensive experiments are performed to illustrate the feasibility and effectiveness of the proposed model on all three level facial activities.

  3. Classifying Facial Actions

    Science.gov (United States)

    Donato, Gianluca; Bartlett, Marian Stewart; Hager, Joseph C.; Ekman, Paul; Sejnowski, Terrence J.

    2010-01-01

    The Facial Action Coding System (FACS) [23] is an objective method for quantifying facial movement in terms of component actions. This system is widely used in behavioral investigations of emotion, cognitive processes, and social interaction. The coding is presently performed by highly trained human experts. This paper explores and compares techniques for automatically recognizing facial actions in sequences of images. These techniques include analysis of facial motion through estimation of optical flow; holistic spatial analysis, such as principal component analysis, independent component analysis, local feature analysis, and linear discriminant analysis; and methods based on the outputs of local filters, such as Gabor wavelet representations and local principal components. Performance of these systems is compared to naive and expert human subjects. Best performances were obtained using the Gabor wavelet representation and the independent component representation, both of which achieved 96 percent accuracy for classifying 12 facial actions of the upper and lower face. The results provide converging evidence for the importance of using local filters, high spatial frequencies, and statistical independence for classifying facial actions. PMID:21188284

  4. The Role of Textiles in Dermatitis: An Update.

    Science.gov (United States)

    Mobolaji-Lawal, Motunrayo; Nedorost, Susan

    2015-04-01

    Dermatitis has important implications for individuals who are affected. It can significantly impair function and quality of life. Dermatitis is multi-factorial and often includes elements of atopic dermatitis, allergic contact dermatitis, and irritant contact dermatitis in a co-existent manner. Textiles are in contact with the human skin for extended periods of time and as a result, they are an important part of the cutaneous environment. Thus, it is not surprising that textiles play a major role in both the etiology and the treatment of various types of dermatitis. This review discusses the role of textiles in dermatitis with an emphasis on interesting and recent advances, trends, perspectives, gaps, and conflicts in the field. In addition, we mention other disease processes to be aware of as they can often mimic textile pattern dermatitis. Lastly, we provide a diagnostic approach for patients presenting with textile pattern dermatitis.

  5. Protein contact dermatitis: allergens, pathogenesis, and management.

    Science.gov (United States)

    Levin, Cheryl; Warshaw, Erin

    2008-01-01

    Protein contact dermatitis is an allergic skin reaction induced principally by proteins of either animal or plant origin. The clinical presentation is that of a chronic dermatitis, and it is often difficult to differentiate between allergic contact dermatitis and other eczematous dermatoses. One distinguishing clinical feature is that acute flares of pruritus, urticaria, edema, or vesiculation are noted minutes after contact with the causative substances. Additionally, the patch-test result is typically negative, and the scratch- or prick-test result is positive. The pathogenesis of protein contact dermatitis is unclear but may involve a type I (immunoglobulin E [IgE], immediate) hypersensitivity reaction, type IV (cell-mediated delayed) hypersensitivity reaction, and/or a delayed reaction due to IgE-bearing Langerhans' cells. Management involves avoidance of the allergen.

  6. Atopic dermatitis : risk factors, interventions and costs

    NARCIS (Netherlands)

    Schuttelaar, Maria Louisa Anna

    2012-01-01

    Dit proefschrift beschrijft een aantal patientgebonden onderzoeken op het gebied van constitutioneel eczeem (atopisch eczeem, 'atopic dermatitis'). In hoofdstuk 1 wordt een algemene inleiding over constitutioneel eczeem gegeven. Constitutioneel eczeem is een ontstekingsreactie van de huid die vooral

  7. Bathing and Associated Treatments in Atopic Dermatitis.

    Science.gov (United States)

    Gittler, Julia K; Wang, Jason F; Orlow, Seth J

    2017-02-01

    Atopic dermatitis is one of the most common complaints presenting to dermatologists, and patients typically inquire as to appropriate bathing recommendations. Although many dermatologists, allergists, and primary-care practitioners provide explicit bathing instructions, recommendations regarding frequency of bathing, duration of bathing, and timing related to emollient and medication application relative to bathing vary widely. Conflicting and vague guidelines stem from knowledge related to the disparate effects of water on skin, as well as a dearth of studies, especially randomized controlled trials, evaluating the effects of water and bathing on the skin of patients with atopic dermatitis. We critically review the literature related to bathing and associated atopic dermatitis treatments, such as wet wraps, bleach baths, bath additives, and balneotherapy. We aim to provide readers with a comprehensive understanding of the impact of water and related therapies on atopic dermatitis as well as recommendations based upon the published data.

  8. Hot Tub Rash (Pseudomonas Dermatitis/Folliculitis)

    Science.gov (United States)

    ... Español [PDF - 1 page] "Hot Tub Rash" ( Pseudomonas Dermatitis / Folliculitis) If contaminated water comes in contact ... is often caused by infection with the germ Pseudomonas aeruginosa . This germ is common in the environment ( ...

  9. Compositae dermatitis from airborne parthenolide

    DEFF Research Database (Denmark)

    Paulsen, E.; Christensen, Lars Porskjær; Andersen, K.E.

    2007-01-01

    -allergic patients and (ii) re-assess the role of PHL and other SQLs in airborne contact allergy. PATIENTS AND METHODS: Feverfew-allergic patients were patch tested with extracts and fractions containing volatile monoterpenes and sesquiterpenes as well as extracts of airborne particles from flowering feverfew plants......, whether they were oxidized or not. CONCLUSIONS: The clinical results have proved that some feverfew-allergic patients are sensitive to airborne particles released from the plant, and isolation of PHL from the particle-containing HIVAS extract in allergenic amounts is strong evidence of PHL......BACKGROUND: Compositae dermatitis confined to exposed skin has often been considered on clinical grounds to be airborne. Although anecdotal clinical and plant chemical reports suggest true airborne allergy, no proof has been procured. Feverfew (Tanacetum parthenium) is a European Compositae plant...

  10. OCULAR COMPLICATIONS IN ATOPIC DERMATITIS

    Institute of Scientific and Technical Information of China (English)

    SHEN Xi; XU Ge-zhi; JIAO Qin; LI Xia; SHI Ruo-fei

    2008-01-01

    Objective To describe the ocular complications of 62 patients with active atopic dermatitis( AD) during the period of 2003 2006. Methods Routine ophthalmic examinations, including slit-lamp microscope, indirect ophthalmoscope or Goldmann three-mirror lens, A-scan and B-scan ultrasound, ultrasound biomicroscope (UBM) and corneal topography, as well as tear film break-up time (BUT) and Schirmer tests were carried out. Results Cataract (28 eyes), keratoconjunctivitis (42 eyes), superficial punctate keratopathy (45 eyes) and tear function abnormality ( 76 eyes) were major ocular complications in AD patients. Retinal detachment (6 eyes) was the most severe ocular complication in the AD patients. Conclusion Ocular complications are common in AD patients and a very careful examination of eyes is essential in treating AD patients. If the eyes can be examed carefully and in time, some operations and severe complications can be avoidable, especially for the patients with retinal breaks or retinal detachment.

  11. Contact dermatitis in cement workers in Isfahan

    Directory of Open Access Journals (Sweden)

    Iraji Fariba

    2006-01-01

    Full Text Available BACKGROUND: Due to recent industrialization and inadequately protected workers or in other words poor supervision on constructive workers habits in our large city of Isfahan cement contact dermatitis is relatively high especially among cement factory workers and constructive personnel. PURPOSES: To investigate the prevalence rate of cement contact dermatitis in cement factory workers in Isfahan. METHODS: A case-control clinical study was carried out by randomly selecing 150 factory workders and 150 official clerks in a cement factory in Isfahan in 2001. After a complete physical examination, data was recorded in observational checklists. FINDINGS: The percentages of contact dermatitis prevalences in the first and the second groups were 22% and 5.3% respectively. About 60% of cement workers with contact dermatitis were between 30-40 years of age. There was a direct relationship with age in both groups of the workers. In the high-exposure group, the hand eczema along was 70% but in the other group the percentage of involvement was the same in exposed and unexposed anatomical areas. CONCLUSIONS: There was a direct relationship between occurrence and the severity of involvement and duration of contact in the first group. Cent percent of cement workers had contact dermatitis after 10 or less years, but the percentage among the other group was 35%. LIMITATION: Irritant contact dermatitis to cement has not been detected.

  12. ATOPIC DERMATITIS: NEW ASPECTS OF TREATMENT

    Directory of Open Access Journals (Sweden)

    D. Sh. Macharadze

    2013-01-01

    Full Text Available Atopic dermatitis is a chronic inflammatory cutaneous disease, which demands a prolonged treatment. A modern views on the main approaches to treatment of atopic dermatitis in children and adults are analyzed in this article. The treatment is based on the permanent use of emollients in order to achieve an anti-inflammatory effect — topical calcineurin inhibitors (tacrolimus and pimecrolimus, and short courses (5 days of topical corticosteroids during relapses. For the 10-year period of topical calcineurin inhibitors usage in treatment of atopic dermatitis a great amount of experimental and clinical data have been accumulated. Two the most important changes and additions in the treatment of atopic dermatitis in recent times were related to a new hypothesis of proactive therapy with the use of topical tacrolimus and closing of «black box» warnings, associated to malignization risk due to the long-term usage of topical calcineurin inhibitors. Since atopic dermatitis is characterized by relapsing course, nowadays topical tacrolimus should be considered the most appropriate treatment approach, both in adults and children. The results of investigations confirmed more than 6-times decrease in relapse rate, as well as the significant improvement of quality of life, when the above-mentioned treatment scheme is used, both in children and adults.Key words: children, atopic dermatitis, emollients, treatment, tacrolimus.

  13. A novel topical agent in the treatment of seborrheic keratoses: A proof of concept study by clinical and dermoscopic evaluation.

    Science.gov (United States)

    Lacarrubba, Francesco; Nasca, Maria Rita; Verzì, Anna Elisa; Micali, Giuseppe

    2017-08-10

    In this proof of concept study, 50 lesions from 15 patients with multiple seborrheic keratoses (SKs) were treated with a novel aqueous solution containing nitric acid, zinc and copper salts, and organic acids (acetic, lactic, and oxalic acid). Treatment consisted in the application of an amount of the solution sufficient to obtain a whitening/yellowish reaction. Application of the nitric-zinc solution was performed every other week until clinical and dermoscopic clearance or crust formation, for a maximum of 4 applications. Efficacy evaluation was performed at 8 weeks (T1) and 6 months (T2). All subjects, who reported no or minimal discomfort during and after the application of the solution, completed the study. At T1, a complete clinical and dermoscopic resolution was observed in 37 lesions after an average of 3 applications/lesion (range 2-4). A partial response, with minimal persistent residual spots, was detected in the remaining 13 lesions. All patients with complete clearance showed no relapses at a 6-month follow-up (T2). The positive preliminary results indicate that this novel solution may represent a promising alternative option for SKs especially in patients not keen or eligible to undergo invasive tissue-destructive procedures. © 2017 Wiley Periodicals, Inc.

  14. Intraepidermal proliferation of Merkel cells within a seborrheic keratosis: Merkel cell carcinoma in situ or Merkel cell hyperplasia?

    Science.gov (United States)

    McFalls, Jeanne; Okon, Lauren; Cannon, Sarah; Lee, Jason B

    2017-05-01

    Intradepidermal proliferation of Merkel cells without any dermal component has been interpreted as either a hyperplastic process secondary to chronic ultraviolet radiation or a neoplastic process, namely Merkel cell carcinoma (MCC) in situ. The recent criteria that have been proffered to diagnose MCC in situ, unfortunately, are identical to those that have been applied to Merkel cell hyperplasia in the past, posing a diagnostic quandary when faced with an intraepidermal proliferation of Merkel cells. Most previously reported cases of MCC in situ have occurred within associated epithelial lesion that includes solar (actinic) keratosis and squamous-cell carcinoma in situ. Similarly, Merkel cell hyperplasia has been reported to occur in association with a variety of epithelial lesions as well as on chronically sun-damaged skin. Herein, a case of an intraepidermal proliferation of Merkel cells within a seborrheic keratosis is presented accompanied by a discussion on whether the proliferation represents another case of Merkel cell carcinoma in situ or an incidental hyperplastic process on chronically sun-damaged skin. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  15. Adolescents with HIV and facial lipoatrophy: response to facial stimulation

    OpenAIRE

    Jesus Claudio Gabana-Silveira; Laura Davison Mangilli; Sassi, Fernanda C.; Arnaldo Feitosa Braga; Claudia Regina Furquim de Andrade

    2014-01-01

    OBJECTIVES: This study evaluated the effects of facial stimulation over the superficial muscles of the face in individuals with facial lipoatrophy associated with human immunodeficiency virus (HIV) and with no indication for treatment with polymethyl methacrylate. METHOD: The study sample comprised four adolescents of both genders ranging from 13 to 17 years in age. To participate in the study, the participants had to score six or less points on the Facial Lipoatrophy Index. The facial stim...

  16. Assessing Pain by Facial Expression: Facial Expression as Nexus

    OpenAIRE

    Prkachin, Kenneth M.

    2009-01-01

    The experience of pain is often represented by changes in facial expression. Evidence of pain that is available from facial expression has been the subject of considerable scientific investigation. The present paper reviews the history of pain assessment via facial expression in the context of a model of pain expression as a nexus connecting internal experience with social influence. Evidence about the structure of facial expressions of pain across the lifespan is reviewed. Applications of fa...

  17. Neuromuscular retraining for facial paralysis.

    Science.gov (United States)

    Diels, H J; Combs, D

    1997-10-01

    Neuromuscular retraining is an effective method for rehabilitating facial musculature in patients with facial paralysis. This nonsurgical therapy has demonstrated improved functional outcomes and is an important adjunct to surgical treatment for restoring facial movement. Treatment begins with an intensive clinical evaluation and incorporates appropriate sensory feedback techniques into a patient-specific, comprehensive, home therapy program. This article discusses appropriate patients, timelines for referral, and basic treatment practices of facial neuromuscular retraining for restoring function and expression to the highest level possible.

  18. Topical ketoconazole therapy in a recalcitrant case of seborrhoeic dermatitis

    Directory of Open Access Journals (Sweden)

    Baishya B

    1996-01-01

    Full Text Available Ketoconazole 2% cream and 2% shampoo were found to be effective in controlling seborrhoeic dermatitis in a recalcitrant case. This topical ketoconazole therapy seems to be better than other conventional topical preparations prescribed in seborrhoeic dermatitis.

  19. Computer facial animation

    CERN Document Server

    Parke, Frederic I

    2008-01-01

    This comprehensive work provides the fundamentals of computer facial animation and brings into sharper focus techniques that are becoming mainstream in the industry. Over the past decade, since the publication of the first edition, there have been significant developments by academic research groups and in the film and games industries leading to the development of morphable face models, performance driven animation, as well as increasingly detailed lip-synchronization and hair modeling techniques. These topics are described in the context of existing facial animation principles. The second ed

  20. Facial Data Field

    Institute of Scientific and Technical Information of China (English)

    WANG Shuliang; YUAN Hanning; CAO Baohua; WANG Dakui

    2015-01-01

    Expressional face recognition is a challenge in computer vision for complex expressions. Facial data field is proposed to recognize expression. Fundamentals are presented in the methodology of face recognition upon data field and subsequently, technical algorithms including normalizing faces, generating facial data field, extracting feature points in partitions, assigning weights and recog-nizing faces. A case is studied with JAFFE database for its verification. Result indicates that the proposed method is suitable and eff ective in expressional face recognition con-sidering the whole average recognition rate is up to 94.3%. In conclusion, data field is considered as a valuable alter-native to pattern recognition.

  1. Facial palsy after blunt trauma and without facial bone fracture.

    Science.gov (United States)

    Coltro, Pedro Soler; Goldenberg, Dov Charles; Aldunate, Johnny Leandro Conduta Borda; Alessi, Mariana Sisto; Chang, Alexandre Jin Bok Audi; Alonso, Nivaldo; Ferreira, Marcus Castro

    2010-07-01

    A 14-year-old patient had a low-energy facial blunt trauma that evolved to right facial paralysis caused by parotid hematoma with parotid salivary gland lesion. Computed tomography and angiography demonstrated intraparotid collection without pseudoaneurysm and without radiologic signs of fracture in the face. The patient was treated with serial punctures for hematoma deflation, resolving with regression and complete remission of facial paralysis, with no late sequela. The authors discuss the relationship between facial nerve traumatic injuries associated or not with the presence of facial fractures, emphasizing the importance of early recognition and appropriate treatment of such cases.

  2. Allergic contact dermatitis: immune system involvement and distinctive clinical cases.

    Science.gov (United States)

    Imbesi, S; Minciullo, P L; Isola, S; Gangemi, S

    2011-01-01

    The aim of this review is drawing the attention to the contact dermatitis, an inflammatory skin condition due to pro-inflammatory and toxic factors able to activate the skin innate immunity (irritant contact dermatitis) or caused by a T-cell- mediated hypersensitivity reaction (allergic contact dermatitis). The immune system involvement and a variety of clinical pictures are described in order to better diagnose, prevent and treat allergic contact dermatitis.

  3. Metal Allergy and Systemic Contact Dermatitis: An Overview

    OpenAIRE

    Yoko Yoshihisa; Tadamichi Shimizu

    2012-01-01

    Contact dermatitis is produced by external skin exposure to an allergen, but sometimes a systemically administered allergen may reach the skin and remain concentrated there with the aid of the circulatory system, leading to the production of systemic contact dermatitis (SCD). Metals such as nickel, cobalt, chromium, and zinc are ubiquitous in our environment. Metal allergy may result in allergic contact dermatitis and also SCD. Systemic reactions, such as hand dermatitis or generalized eczema...

  4. Effects on Nursing Intervention for the Treatment of Seborrheic Alopecia%护理干预对脂溢性脱发治疗的影晌

    Institute of Scientific and Technical Information of China (English)

    邝瑞明; 黄春容

    2011-01-01

    目的:探讨护理干预对脂溢性脱发治疗的影响.方法:将80例脂溢性脱发患者随机分为2组.常规组(31例)予自拟脱发方治疗,干预组(49例)在脱发方治疗的基础上对患者的心理、饮食和生活进行护理干预,观察2组疗效的差异性.结果:干预组的治疗效果优于常规组(P<0.01).结论:护理干预对脂溢性脱发的治疗有着积极的作用,能够提高脂溢性脱发的疗效.%Objective:To explore the effects on nursing intervention for the treatment of seborrheic alopecia. Method:80 patients with seborrheic alopecia were randomly divided into 2 groups.Conventional group (31 cases) received self-made TuoFaFang of TCM. Intervention group (49 cases) received the nursing intervention of psychology, dietary and life on the basis of self-made TuoFaFang.The treatment differences were observed. ResultThe therapeutic effect in the intervention group is better than in the conventional treatment group (P<0.01).Conclusion:Nursing intervention had a positive effect and can improve treatment outcome for the treatment of seborrheic alopecia.

  5. A Rare Comorbidity: Dermatitis Herpetiformis and Sarcoidosis - A Case Report

    Directory of Open Access Journals (Sweden)

    Ivanov Pavlov Stoyan

    2016-09-01

    Full Text Available Sarcoidosis is an enigmatic, multisystem granulomatous disease of unknown etiology and wide range of clinical presentations. Case report: A 54-year-old female presented with facial rash: polymorphic, round, infiltrated erythematous plaques, 1 - 3 cm in size, disseminated on several areas of the face. The medical history was consistent with dermatitis herpetiformis and persistent intrahepatic cholestasis. The laboratory test results suggested celiac disease (strong positivity of IgA anti-tissue transglutaminase antibodies but upper endoscopy was not performed to confirm it. The skin biopsy revealed noncaseating epithelioid-cell granulomas, and negative direct immunofluorescence showed IgA deposits in the dermis. Sarcoidosis with cutaneous and hepatic involvement was established based on compatible clinical findings and supportive histology. The period between manifestations of Duhring disease and skin manifestations of sarcoidosis was 20 years. Conclusion: Our clinical case supports the hypothesis for common immune pathogenic factors in gluten-sensitive diseases and sarcoidosis. The simultaneous occurrence of celiac disease and sarcoidosis is rare, but should not be under recognized.

  6. Black-spot poison ivy dermatitis. An acute irritant contact dermatitis superimposed upon an allergic contact dermatitis.

    Science.gov (United States)

    Hurwitz, R M; Rivera, H P; Guin, J D

    1984-08-01

    A black spot in the epidermis over a blister of poison ivy dermatitis is an uncommon finding. Four patients with the phenomenon are described. Histologic and histochemical studies were made on biopsy material and the blackish deposit on the skin surface was compared with black deposits in and on leaves of the species of poison ivy. This examination revealed a yellow, amorphous substance on the stratum corneum of the lesions and a similar substance in and on leaves of the poison ivy plant, Toxicodendron radicans ssp. negundo. Associated with the pigmentary deposits there were distinct changes of acute irritant contact dermatitis superimposed upon allergic contact dermatitis. Our findings support the view that the black material is the oleoresin of the plant, and that this substance behaves both as an irritant and an allergen.

  7. Occupational contact dermatitis in painters - an analysis of patch test data from the Danish Contact Dermatitis Group

    DEFF Research Database (Denmark)

    Mose, Anja P; Lundov, Michael Dyrgaard; Zachariae, Claus

    2012-01-01

    Background. Painters are among the occupational groups that most commonly experience occupational contact dermatitis, but few investigations exist concerning this occupation. Objectives. To characterize painters with contact dermatitis and identify the most common allergens associated with the oc...

  8. Paederus fuscipes dermatitis. A histopathological study.

    Science.gov (United States)

    Borroni, G; Brazzelli, V; Rosso, R; Pavan, M

    1991-10-01

    Paederus fuscipes (PF) dermatitis is a self-healing blistering disorder of the skin caused by a small insect belonging to genus Paederus, family Staphylinidae, order Coleoptera. Crushing PF on the skin causes acute dermatitis within 24 hours, corresponding in shape and dimensions to the area affected by the substance released (pederin). The acute vesicular lesions become crusted and scaly within a few days and heal completely in 10-12 days, with a transitory postinflammatory hypercromic patch. Twenty consecutive cases of PF dermatitis at different stages were studied histologically by routine light microscopy. The pederin causes a spectrum of histopathologic changes ranging from acute epidermal necrosis and blistering in acute stages, to marked acanthosis with mitotic figures in the late stages. PF dermatitis is an entomological model of irritant contact dermatitis, having histopathologic features of intraepidermal and subepidermal blistering, epidermal necrosis and acantholysis. The presence of some acantholytic foci, relatively far from the foci of clinically involved skin, in four of the cases considered suggests a possible role of pederin in inducing acantholysis indirectly. Acantholysis is probably caused by the release of epidermal proteases.

  9. DERMATITIS PELAGROSA. REPORTE DE CASO.

    Directory of Open Access Journals (Sweden)

    Frank C. Alvarez-Li

    2010-01-01

    Full Text Available La pelagra es una enfermedad cada vez menos frecuente. Debida a una deficiencia de niacina en la dieta, principalmente, en áreas donde la alimentación es muy deficiente y/o el consumo de alcohol es importante. La pelagra o síndrome de las tres D, se caracteriza por demencia, dermatitis y diarrea.Se reporta un caso donde predominaron las lesiones localizadas en la piel de la cara, región anterior del cuello, brazos, antebrazos, dorso de las manos, tercio distal de las piernas y dorso de los pies, de tipo eritematoescamosas, con zonas agrietadas y descamación de la piel y despigmentación en otras áreas bien delimitadas en relación con la piel normal.El tratamiento con Nicotinamida produjo notable mejoría de las lesiones en piel. En evaluación posterior al alta las lesiones en piel habían desaparecidos.

  10. Allergic contact dermatitis from oleyl alcohol in Elidel cream

    DEFF Research Database (Denmark)

    Andersen, Klaus Ejner; Broesby-Olsen, Sigurd

    2006-01-01

    We report an atopic dermatitis patient with recurrent hand dermatitis who developed a severe allergic contact dermatitis from the use of Elidel cream. Diagnostic patch tests showed an isolated contact allergy to the emulsifier oleyl alcohol present in the product. Pimecrolimus appeared to have had...

  11. Recalcitrant atopic dermatitis due to allergy to Compositae.

    NARCIS (Netherlands)

    Wintzen, M.; Donker, AS; Zuuren, van EJ

    2003-01-01

    Atopic dermatitis is often complicated by allergic contact dermatitis, although patch testing may reveal positive reactions of uncertain relevance. We report a case of a 35-year-old woman with recalcitrant atopic dermatitis, with a positive patch-test reaction to Compositae mix (CM). Initially, sens

  12. Dermatitis neglecta -- A dirty dermatosis: Report of three cases

    Directory of Open Access Journals (Sweden)

    Abhijit Saha

    2015-01-01

    Full Text Available Dermatitis neglecta is a condition that results from inadequate frictional cleansing leading to accumulation of corneocytes, sebum and sweat ultimately resulting in hyper-pigmented patch or verrucous plaque. Recognizing this condition avoids unnecessary, aggressive diagnostic and therapeutic procedures. Here we report three cases of dermatitis neglecta in whom the dermatitis developed as a result of intentional neglect of personal hygiene.

  13. Anatomical patterns of dermatitis in adult filaggrin mutation carriers

    DEFF Research Database (Denmark)

    Heede, Nina G; Thyssen, Jacob Pontoppidan; Thuesen, Betina H;

    2015-01-01

    BACKGROUND: Common filaggrin (FLG) null mutations are associated with severe and early onset of atopic dermatitis (AD). To date, few studies have investigated anatomical patterns of dermatitis and none has been conducted in the general population. OBJECTIVE: We evaluated patterns of dermatitis in...

  14. Multiracial Facial Golden Ratio and Evaluation of Facial Appearance.

    Science.gov (United States)

    Alam, Mohammad Khursheed; Mohd Noor, Nor Farid; Basri, Rehana; Yew, Tan Fo; Wen, Tay Hui

    2015-01-01

    This study aimed to investigate the association of facial proportion and its relation to the golden ratio with the evaluation of facial appearance among Malaysian population. This was a cross-sectional study with 286 randomly selected from Universiti Sains Malaysia (USM) Health Campus students (150 females and 136 males; 100 Malaysian Chinese, 100 Malaysian Malay and 86 Malaysian Indian), with the mean age of 21.54 ± 1.56 (Age range, 18-25). Facial indices obtained from direct facial measurements were used for the classification of facial shape into short, ideal and long. A validated structured questionnaire was used to assess subjects' evaluation of their own facial appearance. The mean facial indices of Malaysian Indian (MI), Malaysian Chinese (MC) and Malaysian Malay (MM) were 1.59 ± 0.19, 1.57 ± 0.25 and 1.54 ± 0.23 respectively. Only MC showed significant sexual dimorphism in facial index (P = 0.047; Pmean score of 2.18 ± 0.97 for overall impression and 2.15 ± 1.04 for facial parts, compared to MM and MI, with mean score of 1.80 ± 0.97 and 1.64 ± 0.74 respectively for overall impression; 1.75 ± 0.95 and 1.70 ± 0.83 respectively for facial parts. 1) Only 17.1% of Malaysian facial proportion conformed to the golden ratio, with majority of the population having short face (54.5%); 2) Facial index did not depend significantly on races; 3) Significant sexual dimorphism was shown among Malaysian Chinese; 4) All three races are generally satisfied with their own facial appearance; 5) No significant association was found between golden ratio and facial evaluation score among Malaysian population.

  15. Diplegia facial traumatica

    Directory of Open Access Journals (Sweden)

    J. Fortes-Rego

    1975-12-01

    Full Text Available É relatado um caso de paralisia facial bilateral, incompleta, associada a hipoacusia esquerda, após traumatismo cranioencefálico, com fraturas evidenciadas radiológicamente. Algumas considerações são formuladas tentando relacionar ditas manifestações com fraturas do osso temporal.

  16. Management of facial blushing

    DEFF Research Database (Denmark)

    Licht, Peter B; Pilegaard, Hans K

    2008-01-01

    an indication for treatment, facial blushing may be treated effectively by thoracoscopic sympathectomy. The type of blushing likely to benefit from sympathectomy is mediated by the sympathetic nerves and is the uncontrollable, rapidly developing blush typically elicited when one receives attention from other...

  17. Facial Paralysis Reconstruction.

    Science.gov (United States)

    Razfar, Ali; Lee, Matthew K; Massry, Guy G; Azizzadeh, Babak

    2016-04-01

    Facial nerve paralysis is a devastating condition arising from several causes with severe functional and psychological consequences. Given the complexity of the disease process, management involves a multispecialty, team-oriented approach. This article provides a systematic approach in addressing each specific sequela of this complex problem.

  18. Paralisia facial bilateral

    Directory of Open Access Journals (Sweden)

    J. Fortes-Rego

    1976-03-01

    Full Text Available É apresentado um caso de diplegia facial surgida após meningite meningocócica e infecção por herpes simples. Depois de discutir as diversas condições que o fenômeno pode apresentar-se, o autor inclina-se por uma etiologia herpética.

  19. Novel Facial Features Segmentation Algorithm

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    An efficient algorithm for facial features extractions is proposed. The facial features we segment are the two eyes, nose and mouth. The algorithm is based on an improved Gabor wavelets edge detector, morphological approach to detect the face region and facial features regions, and an improved T-shape face mask to locate the extract location of facial features. The experimental results show that the proposed method is robust against facial expression, illumination, and can be also effective if the person wearing glasses, and so on.

  20. Radiation recall dermatitis induced by trastuzumab.

    Science.gov (United States)

    Moon, Dochang; Koo, Ja Seung; Suh, Chang-Ok; Yoon, Chang Yun; Bae, Jaehyun; Lee, Soohyeon

    2016-01-01

    We report a case of radiation recall dermatitis caused by trastuzumab. A 55-year-old woman with metastatic breast cancer received palliative first-line trastuzumab/paclitaxel and a salvage partial mastectomy with lymph node dissection was subsequently performed. In spite of the palliative setting, the pathology report indicated that no residual carcinoma was present, and then she underwent locoregional radiotherapy to ensure a definitive response. After radiotherapy, she has maintained trastuzumab monotherapy. Nine days after the fifth cycle of trastuzumab monotherapy, dermatitis in previously irradiated skin developed, with fever. Radiation recall dermatitis triggered by trastuzumab is extremely rare. A high fever developed abruptly with a skin rash. This may be the first case of this sort to be reported.

  1. Recent Trends in Occupational Contact Dermatitis.

    Science.gov (United States)

    Wiszniewska, Marta; Walusiak-Skorupa, Jolanta

    2015-07-01

    Occupational contact dermatitis (OCD) remains prevalent among workers and impacts quality of life and workability. The purpose of this review is to summarize the recent advances in occupational contact dermatitis as well as potential hazardous agents in the workplaces causing OCD. The review covers new developments in the epidemiology, etiology, diagnosis, and management of occupational contact dermatitis. This article also provides updated information on the prevalence of work-related skin symptoms and on new contact allergens among working population. It is emphasized that in the context of prevention of OCD, special attention should be focused on the identified high-risk occupational groups, especially healthcare workers and hairdressers starting with the apprentices. Current approaches include working out the standards and guidelines to improve the education, knowledge, diagnosis, and management of OCD based on a multidisciplinary team of medical specialists and an employer.

  2. Allergic Contact Dermatitis Induced by Textile Necklace

    Directory of Open Access Journals (Sweden)

    Uffe Nygaard

    2013-11-01

    Full Text Available Allergic contact dermatitis to textile dyes is considered to be a rare phenomenon. A recent review reported a prevalence of contact allergy to disperse dyes between 0.4 and 6.7%. The relevance of positive patch testing was not reported in all studies. Textile dye allergy is easily overlooked and is furthermore challenging to investigate as textile dyes are not labelled on clothing. In this report, we present a case of allergic contact dermatitis to a textile necklace. The patch test showed strong reactions to the necklace and the azo dyes Disperse Orange 1 and Disperse Yellow 3. Despite the European legislation and the reduced use of disperse dyes in Third World countries, disperse azo dyes still induce new cases of allergic contact dermatitis.

  3. Interstitial granulomatous dermatitis secondary to soy.

    Science.gov (United States)

    Dyson, Senait W; Hirsch, Ann; Jaworsky, Christine

    2004-08-01

    A healthy 58-year-old woman developed an asymptomatic papular eruption of the neck, cheek, abdomen, arms, and flexures. There was an 8-year history of the lesions, which had erupted when the patient started a strict vegetarian diet. Lesions lasted 3 to 5 days, cleared without scarring, and were associated with burning and increased tearing of the eyes. The biopsy specimen showed an interstitial granulomatous dermatitis without vascular injury, collagen alteration, or mononuclear atypia. The eruption cleared when the patient omitted soy products from her diet. It subsequently recurred with intake of even minimal amounts of soy. Interstitial granulomatous dermatitis is a histologic pattern of inflammation that generates a broad differential diagnosis. No previous reports of interstitial granulomatous dermatitis related to soy products are available in the literature.

  4. Contact dermatitis to a limb prosthesis.

    Science.gov (United States)

    Sood, Apra; Taylor, James S; Billock, John N

    2003-09-01

    PROSTHESIS USERS commonly develop various skin problems on the residual limb, directly under the prosthetic device when the device is in direct contact with the skin. Prolonged occlusion and humidity increase the likelihood of developing contact sensitivity to moisturizing creams, medicaments, and materials in the prosthesis itself.1 Allergic contact dermatitis to various prosthetic design materials is uncommon, and the relevance of positive patch-test results to chemicals present in prostheses may be difficult to establish. Most reports of allergic contact dermatitis to prostheses have been concerned with surgical amputees and not congenital amputees. We report a 5-year-old boy with a transverse partial hemimelia who developed allergic contact dermatitis to an adhesive used in his myoelectric prosthesis. Unlike most prostheses, myoelectric prostheses are worn directly against the skin, for surface electromyography electrode contact.

  5. Allergic contact dermatitis in children and adolescents

    DEFF Research Database (Denmark)

    Mørtz, Charlotte G; Andersen, Klaus Ejner

    1999-01-01

    From a clinical point of view, the prevalence of allergic contact dermatitis (ACD) among children and adolescents seems to be low. However, many children have dermatitis, most often atopic dermatitis. In selected cases, ACD is suspected, and the child is tested. The question remains, whether...... the prevalence of ACD in children really is low or whether the possibility of ACD is not sufficiently considered. During the last decade, reports have appeared on series of children and adolescents with contact allergy and ACD. Few cases have been reported in infants, but the development of contact allergy...... and ACD increases with age. Most studies include selected groups of children and adolescents with suspected ACD. Few studies have examined unselected populations, and most consider only the prevalence of contact allergy without evaluating the clinical relevance, e.g., the prevalence of ACD. Furthermore...

  6. Dermatite esfoliativa: estudo clínico-etiológico de 58 casos Exfoliative dermatitis: clinical and etiologic study of 58 cases

    Directory of Open Access Journals (Sweden)

    Rogério Nabor Kondo

    2006-06-01

    exfoliative dermatitis seen at the Hospital Universitário Regional do Norte do Paraná were reviewed over a ten-year period. RESULTS - A total of 58 patients with diagnosis of exfoliative dermatitis was assessed. Mean age was 56.89 years. The underlying disorder in 33 patients was a skin disease (psoriasis, 11 cases; contact dermatitis, 9 cases; congenital ichthyosiform erythroderma, 3 cases; seborrheic dermatitis, 5 cases; atopic dermatitis, 3 cases; pityriasis rubra pilaris, 2 cases. Drug reactions were observed in 11 patients. Etiology could not be determined in 14 cases (24%. CONCLUSIONS - In a sample of patients attending a reference dermatology center, exfoliative dermatitis was a rare condition, and in most cases it was related to skin diseases.

  7. Identifying the causes of contact dermatitis.

    Science.gov (United States)

    Jones, Ruth; Horn, Helen M

    2014-06-01

    Contact dermatitis results from skin contact with an exogenous substance. It can be caused by direct contact, airborne particles, vapours or light. Individuals of any age can be affected. The two most common variants are irritant contact dermatitis (ICD) and allergic contact dermatitis (ACD). ICD is more common and has a worse prognosis. Other less common forms of contact dermatitis include photocontact allergy and, in food handlers, protein contact dermatitis. ICD is a form of eczema and is induced by direct inflammatory pathways without prior sensitisation. Classical ACD is mediated by type 4 cell-mediated immunity. Sensitisation occurs within 5 to 16 days of skin contact with a potential allergen but at this first exposure there is no inflammation. Frequent exposure and high concentrations of potential allergens increase the risk of sensitisation. If eczema is recurrent/persistent, or occurs in an individual with no previous history of eczema, contact dermatitis should be considered. Dorsal aspects of the hands are most often affected by ICD, usually with involvement of the finger webs. Cumulative effects of water, soaps and detergents are the most common cause of ICD which affects the hands more often than any other site. Nickel, fragrances, rubber accelerators and biocides are the most common sensitisers in ACD. Patients with leg ulcers and stasis eczema are at especially high risk of developing allergies to ingredients of their topical treatments, dressings and bandages. If ACD is suspected the patient should be referred to secondary care for patch testing. Age should not be a deterrent to patch testing. Accurate diagnosis, avoidance of identified allergens and protection from irritants are the key to successful treatment.

  8. DERMATITIS KONTAK AKIBAT KERJA PADA PENATA RAMBUT

    Directory of Open Access Journals (Sweden)

    Shirley M. Oslan

    2013-12-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE MicrosoftInternetExplorer4 Reports from dermatologist, there is an increasing rate of occupational contact dermatitis from years to years. Occupational contact dermatitis, based on its pathophysiology, can be divided into allergic contact dermatitis and irritant contact dermatitis. Unfortunately both have a similar clinical presentation that sometimes difficult to differentiate, but a precise diagnosis is needed to give the most effective treatment. Hairdressers placed in the third rank in the most highly risk occupation for occupational contact dermatitis. Proper identification on tools and materials used in each occupation, method of working, and other risk factors is needed in order to prevent occupational contact dermatitis, for hairdressers in particular. /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin:0in; mso-para-margin-bottom:.0001pt; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  9. Interaction between facial expression and color

    OpenAIRE

    Kae Nakajima; Tetsuto Minami; Shigeki Nakauchi

    2017-01-01

    Facial color varies depending on emotional state, and emotions are often described in relation to facial color. In this study, we investigated whether the recognition of facial expressions was affected by facial color and vice versa. In the facial expression task, expression morph continua were employed: fear-anger and sadness-happiness. The morphed faces were presented in three different facial colors (bluish, neutral, and reddish color). Participants identified a facial expression between t...

  10. Contact dermatitis caused by ethyl alcohol

    Directory of Open Access Journals (Sweden)

    Pasricha J

    1990-01-01

    Full Text Available A 45-year-old lady developed itching and burning sensation in the right cubital fossa, 10 minutes after local application of blue spirit, for withdrawing blood. Erythematous papulo-vesicular lesion appeared in the area after about 8 hours and the dermatitis subsided completely in 5 days with topical fluocinolone acetonide. Two weeks later, she noticed itching and a mild dermatitis on the finger-tips on holding a spirit swab between her fingers. Patch tests resulted in severe papulo-vesicular reactions with blue spirit and absolute ethyl alcohol, but negative reaction with copper sulphate.

  11. Poison ivy dermatitis. Nuances in treatment.

    Science.gov (United States)

    Williford, P M; Sheretz, E F

    1994-02-01

    Acute allergic contact dermatitis due to poison ivy or poison oak is a common presenting complaint in the practices of many primary care physicians. While the clinical features are well described, reported treatment regimens vary in both topical and systemic therapies. We review herein the variability of presenting morphologic features of the disease and common treatment regimens, with attention given to complications of therapy. We also comment on the correct botanical designation, incidence, and immune mechanisms of the disease state and review measures to avoid allergic contact dermatitis due to poison ivy and poison oak.

  12. Current clinical practice in atopic dermatitis.

    Science.gov (United States)

    Odedra, Katy Mara

    2014-08-12

    Atopic dermatitis affects both children and adults, and often presents in early life as itchy, dry skin primarily located on the face, trunk and limbs. There is usually a history of family or personal atopic disease and an increased blood level of the allergic antibody immunoglobulin E. The mainstays of treatment are emollients and corticosteroid ointments and/or creams. Other therapies include immunomodulators and management of any associated infections. Caring for a patient with atopic dermatitis requires skilled assessment, effective education and the ability to involve and support patients and carers in the management of this condition.

  13. Atopic dermatitis and the nervous system.

    Science.gov (United States)

    Misery, Laurent

    2011-12-01

    Due to the narrow associations between the skin, immune system, and nervous system, nerve endings are very important in the pathophysiology of inflammatory dermatoses and especially in atopic dermatitis. Many neurotransmitters and nerve growth factors that are released in blood or skin are involved in neurogenic inflammation, which dramatically enhance the inflammation induced by immune cells. During times of stress, their release is highly enhanced. In atopic dermatitis lesions, there are many specific changes in skin neurobiology and neurophysiology. These interesting data suggest that novel therapeutic possibilities can be imagined.

  14. Atopic dermatitis from adolescence to adulthood in the TOACS cohort

    DEFF Research Database (Denmark)

    Mørtz, Charlotte G; Andersen, K E; Dellgren, C

    2015-01-01

    BACKGROUND: While much is known about childhood atopic dermatitis, little is known about persistence of atopic dermatitis into adult life. We report, to our knowledge for the first time, the clinical course of atopic dermatitis in an unselected cohort of adolescents followed into adulthood. METHODS......: The course of atopic dermatitis from adolescence to adulthood was studied prospectively in a cohort of unselected 8th-grade schoolchildren established in 1995 and followed up in 2010 with questionnaire and clinical examination. RESULTS: The lifetime prevalence of atopic dermatitis was high (34...

  15. Immunology of allergic contact dermatitis.

    Science.gov (United States)

    Tončić, Ružica Jurakić; Lipozenčić, Jasna; Martinac, Ivana; Gregurić, Sanja

    2011-01-01

    Allergic contact dermatitis (ACD) is a T-cell mediated skin inflammation caused by repeated skin exposure to contact allergens. This review summarizes current knowledge on the immunology of ACD. Different phases in ACD are distinguished, i.e. sensitization, elicitation and resolution phases. We discuss contact allergen presentation and the central role of antigen presenting cells during sensitization phase. There is an extremely complex interaction of different kinds of immune cells, such as antigen presenting cells, T, B, NK lymphocytes, keratinocytes (KCs), endothelium, mast cells (MCs) and platelets, and this complex interaction is guided through orchestration of numerous cytokines and chemokines. The role of adaptive immunity has been recognized in contact hypersensitivity but we also discuss the important role of some parts of innate immunity such as natural killer T lymphocytes (NKT) and complement system. Cooperation of innate and adaptive immunity, in this case NK cells and B cells, initiates elicitation phase by complement cascade activation, vasoactive substance release and endothelial activation. KCs are not only innocent bystanders, on the contrary, they are involved in all phases of ACD, from the early phase of initiation through sending "danger" signals and activation of innate immunity, through their role in Langerhans cells (LCs) migration, T-cell trafficking, through the height of the inflammatory phase with direct interactions with epidermotropic T-cells, and finally through the resolution phase with the production of anti-inflammatory cytokines and tolerogenic presentation to effector T-cells. Th-1 and Th-17 cells are the main effector cells responsible for tissue damage. At the end, we point out several subsets of T regulatory cells, which exert down-regulatory function and regulate the magnitude and duration of inflammatory reaction.

  16. Sites of dermatitis in a patch test population: hand dermatitis is associated with polysensitization

    DEFF Research Database (Denmark)

    Carlsen, B C; Andersen, K E; Menné, T

    2009-01-01

    . METHODS: A matched case-control study was carried out including 394 polysensitized and 726 single/double-sensitized patients who responded to a postal questionnaire. All subjects were recruited from a hospital patch test population. RESULTS: The hands were the most frequent and the anogenital region...... was the least frequent skin area affected with dermatitis. Dermatitis on the hands/wrists [odds ratio (OR) 1.58], in the armpits (OR 1.56) and on the back (OR 1.91) was positively associated with polysensitization. The hands were the only skin area with dermatitis which maintained the association...... compared with single/double-sensitized patients. CONCLUSIONS: Special awareness in patients with hand dermatitis seems justified either to prevent development of multiple contact allergies or to document polysensitization as an aetiological factor....

  17. Retinotopy of facial expression adaptation.

    Science.gov (United States)

    Matsumiya, Kazumichi

    2014-01-01

    The face aftereffect (FAE; the illusion of faces after adaptation to a face) has been reported to occur without retinal overlap between adaptor and test, but recent studies revealed that the FAE is not constant across all test locations, which suggests that the FAE is also retinotopic. However, it remains unclear whether the characteristic of the retinotopy of the FAE for one facial aspect is the same as that of the FAE for another facial aspect. In the research reported here, an examination of the retinotopy of the FAE for facial expression indicated that the facial expression aftereffect occurs without retinal overlap between adaptor and test, and depends on the retinal distance between them. Furthermore, the results indicate that, although dependence of the FAE on adaptation-test distance is similar between facial expression and facial identity, the FAE for facial identity is larger than that for facial expression when a test face is presented in the opposite hemifield. On the basis of these results, I discuss adaptation mechanisms underlying facial expression processing and facial identity processing for the retinotopy of the FAE.

  18. Realistic facial animation generation based on facial expression mapping

    Science.gov (United States)

    Yu, Hui; Garrod, Oliver; Jack, Rachael; Schyns, Philippe

    2014-01-01

    Facial expressions reflect internal emotional states of a character or in response to social communications. Though much effort has been taken to generate realistic facial expressions, it still remains a challenging topic due to human being's sensitivity to subtle facial movements. In this paper, we present a method for facial animation generation, which reflects true facial muscle movements with high fidelity. An intermediate model space is introduced to transfer captured static AU peak frames based on FACS to the conformed target face. And then dynamic parameters derived using a psychophysics method is integrated to generate facial animation, which is assumed to represent natural correlation of multiple AUs. Finally, the animation sequence in the intermediate model space is mapped to the target face to produce final animation.

  19. Other facial neuralgias.

    Science.gov (United States)

    O'Neill, Francis; Nurmikko, Turo; Sommer, Claudia

    2017-01-01

    Premise In this article we review some lesser known cranial neuralgias that are distinct from trigeminal neuralgia, trigeminal autonomic cephalalgias, or trigeminal neuropathies. Included are occipital neuralgia, superior laryngeal neuralgia, auriculotemporal neuralgia, glossopharyngeal and nervus intermedius neuralgia, and pain from acute herpes zoster and postherpetic neuralgia of the trigeminal and intermedius nerves. Problem Facial neuralgias are rare and many physicians do not see such cases in their lifetime, so patients with a suspected diagnosis within this group should be referred to a specialized center where multidisciplinary team diagnosis may be available. Potential solution Each facial neuralgia can be identified on the basis of clinical presentation, allowing for precision diagnosis and planning of treatment. Treatment remains conservative with oral or topical medication recommended for neuropathic pain to be tried before more invasive procedures are undertaken. However, evidence for efficacy of current treatments remains weak.

  20. Facial resemblance enhances trust.

    Science.gov (United States)

    DeBruine, Lisa M

    2002-07-07

    Organisms are expected to be sensitive to cues of genetic relatedness when making decisions about social behaviour. Relatedness can be assessed in several ways, one of which is phenotype matching: the assessment of similarity between others' traits and either one's own traits or those of known relatives. One candidate cue of relatedness in humans is facial resemblance. Here, I report the effects of an experimental manipulation of facial resemblance in a two-person sequential trust game. Subjects were shown faces of ostensible playing partners manipulated to resemble either themselves or an unknown person. Resemblance to the subject's own face raised the incidence of trusting a partner, but had no effect on the incidence of selfish betrayals of the partner's trust. Control subjects playing with identical pictures failed to show such an effect. In a second experiment, resemblance of the playing partner to a familiar (famous) person had no effect on either trusting or betrayals of trust.

  1. Congenital Facial Teratoma

    OpenAIRE

    Rai, Manjunath; Hegde, Padmaraj; Devaraju, Umesh M.

    2011-01-01

    Teratomas are neoplasm composed of three germinal layers of the embryo that form tissues not normally found in the organ in which they arise. These are most common in the sacrococcygeal region and are rare in the head and neck, which account for less than 6%. An unusual case of facial teratoma in a new born, managed successfully is described here with postoperative follow up of 2 years without any recurrence.

  2. Multiracial Facial Golden Ratio and Evaluation of Facial Appearance.

    Directory of Open Access Journals (Sweden)

    Mohammad Khursheed Alam

    Full Text Available This study aimed to investigate the association of facial proportion and its relation to the golden ratio with the evaluation of facial appearance among Malaysian population. This was a cross-sectional study with 286 randomly selected from Universiti Sains Malaysia (USM Health Campus students (150 females and 136 males; 100 Malaysian Chinese, 100 Malaysian Malay and 86 Malaysian Indian, with the mean age of 21.54 ± 1.56 (Age range, 18-25. Facial indices obtained from direct facial measurements were used for the classification of facial shape into short, ideal and long. A validated structured questionnaire was used to assess subjects' evaluation of their own facial appearance. The mean facial indices of Malaysian Indian (MI, Malaysian Chinese (MC and Malaysian Malay (MM were 1.59 ± 0.19, 1.57 ± 0.25 and 1.54 ± 0.23 respectively. Only MC showed significant sexual dimorphism in facial index (P = 0.047; P<0.05 but no significant difference was found between races. Out of the 286 subjects, 49 (17.1% were of ideal facial shape, 156 (54.5% short and 81 (28.3% long. The facial evaluation questionnaire showed that MC had the lowest satisfaction with mean score of 2.18 ± 0.97 for overall impression and 2.15 ± 1.04 for facial parts, compared to MM and MI, with mean score of 1.80 ± 0.97 and 1.64 ± 0.74 respectively for overall impression; 1.75 ± 0.95 and 1.70 ± 0.83 respectively for facial parts.1 Only 17.1% of Malaysian facial proportion conformed to the golden ratio, with majority of the population having short face (54.5%; 2 Facial index did not depend significantly on races; 3 Significant sexual dimorphism was shown among Malaysian Chinese; 4 All three races are generally satisfied with their own facial appearance; 5 No significant association was found between golden ratio and facial evaluation score among Malaysian population.

  3. New Developments in Biomarkers for Atopic Dermatitis

    NARCIS (Netherlands)

    Thijs, Judith L.; Seggelen, Wouter van; Bruijnzeel-Koomen, Carla; Bruin-Weller, Marjolein de; Hijnen, DirkJan

    2015-01-01

    The application of biomarkers in medicine is evolving. Biomarkers do not only give us a better understanding of pathogenesis, but also increase treatment efficacy and safety, further enabling more precise clinical care. This paper focuses on the current use of biomarkers in atopic dermatitis, new

  4. Interventions for preventing occupational irritant hand dermatitis

    NARCIS (Netherlands)

    Bauer, Andrea; Schmitt, Jochen; Bennett, Cathy; Coenraads, Pieter-Jan; Elsner, Peter; English, John; Williams, Hywel C.

    2010-01-01

    Background Occupational irritant hand dermatitis (OIHD) is an important cause of discomfort in the working population. Different preventive measures are in place but it is not clear how effective these are. Objectives To assess the effect of interventions for preventing OIHD in healthy people who wo

  5. Contact Dermatitis From Topical Application Of Mercurochrome

    Directory of Open Access Journals (Sweden)

    Saha Sib Shankar

    1995-01-01

    Full Text Available Mercury in its metallic from and its other salts may cause contact dermatitis and eczema; but contact allergy due to them is rather uncommon. A case of eczematous reaction due to topical application of mercurochrome developing within one day is being reported.

  6. Contact Dermatitis From Topical Application Of Mercurochrome

    OpenAIRE

    Saha Sib Shankar; Manjumdar Sabyasachi

    1995-01-01

    Mercury in its metallic from and its other salts may cause contact dermatitis and eczema; but contact allergy due to them is rather uncommon. A case of eczematous reaction due to topical application of mercurochrome developing within one day is being reported.

  7. Nosocomial dermatitis caused by Dermanyssus gallinae.

    Science.gov (United States)

    Bellanger, A P; Bories, C; Foulet, F; Bretagne, S; Botterel, F

    2008-03-01

    The mite Dermanyssus gallinae may cause pruritic dermatitis in humans. We describe a case of nosocomial infestation with D. gallinae from an abandoned pigeon nest suspended on the front wall of the Hôpital Henri Mondor near a window. Close surveillance and regular destruction of pigeon nests could prevent these incidents of infection in humans.

  8. Association of atopic dermatitis with smoking

    DEFF Research Database (Denmark)

    Kantor, Robert; Kim, Ashley; Thyssen, Jacob P

    2016-01-01

    BACKGROUND: Tobacco exposure might be a modifiable risk factor for atopic dermatitis (AD). OBJECTIVE: We examine the association between AD and exposure to tobacco smoke. METHODS: We performed a systematic review and meta-analysis of observational studies (n = 86) in MEDLINE, EMBASE, Scopus...

  9. Novel investigational therapies for atopic dermatitis

    DEFF Research Database (Denmark)

    Ibler, Kristina Sophie; Jemec, Gregor Be

    2015-01-01

    Introduction: Atopic dermatitis (AD) is a common skin disease. Although most patients are well served by existing therapies, a subset of patients with severe AD are still not adequately treated. An improved understanding of the pathogenic mechanisms behind the disease has led to the development...

  10. PREVALENCE OF HAND DERMATITIS IN DIFFERENT OCCUPATIONS

    NARCIS (Netherlands)

    SMIT, HA; COENRAADS, PJ

    The prevalence of hand dermatitis in different occupational groups was estimated using a standardized questionnaire in a series of surveys among workers of a chemical company, a municipal electricity company, municipal public works, nurses and surgical assistants. A survey in a sample of the general

  11. Interventions for preventing occupational irritant hand dermatitis

    NARCIS (Netherlands)

    Bauer, Andrea; Schmitt, Jochen; Bennett, Cathy; Coenraads, Pieter-Jan; Elsner, Peter; English, John; Williams, Hywel C.

    2010-01-01

    Background Occupational irritant hand dermatitis (OIHD) is an important cause of discomfort in the working population. Different preventive measures are in place but it is not clear how effective these are. Objectives To assess the effect of interventions for preventing OIHD in healthy people who

  12. Contact dermatitis caused by ECG electrode paste.

    Science.gov (United States)

    Cochran, R J; Rosen, T

    1980-12-01

    A case of contact dermatitis caused by ECG electrode cream is presented and the pertinent literature is reviewed. Our patient was found to be allergic to propylene glycol. Patch-testing remains an invaluable tool in the evaluation of patients suspected of being allergic to ECG paste, creams, and gels.

  13. Contact dermatitis due to Alstroemeria (Peruvian lily).

    Science.gov (United States)

    Apted, J H

    1990-01-01

    Two cases of hand dermatitis due to contact with the plant Alstroemeria (Peruvian Lily) are recorded. This plant has been increasingly used for making floral decorations during the last decade. As it is available throughout the year in Victoria more cases are likely to be discovered in the community.

  14. Occupational issues of allergic contact dermatitis

    DEFF Research Database (Denmark)

    Andersen, Klaus E

    2003-01-01

    -effect relationships to be established with increased certainty. For prevention of allergic contact dermatitis it was a major step forward, with mandatory ingredient labelling of cosmetic products. However, improved labelling of the presence of contact allergens in household and industrial products is needed...

  15. Dermatitis herpetiformis intolerant to dapsone in Aids

    Directory of Open Access Journals (Sweden)

    Krishna K

    1999-01-01

    Full Text Available A 35-year-old man with AIDS and pulmonary tuberculosis presented with lesions suggestive of dermatitis herpetiformis and intolerance to dapsone. He was managed successfully with a combination of nicotinamide 200 mg/day and indomethacin 75 mg/day, topical steroids and gluten free diet.

  16. Consort contact dermatitis due to oak moss.

    Science.gov (United States)

    Held, J L; Ruszkowski, A M; Deleo, V A

    1988-02-01

    An allergic contact dermatitis in a woman was found to be due to oak moss in her husband's after-shave lotion. When routine patch testing reveals a positive reaction, the dermatologist should consider exposure to the antigen not only in the patient but also through contact with the patient's consort.

  17. Contact dermatitis caused by dimethylfumarate in Argentina.

    Science.gov (United States)

    Lo Balbo, A; Gotelli, M J; Mac Cormack, W P; Kogan, N; Gotelli, C

    2011-07-01

    For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.

  18. Radiation recall dermatitis induced by trastuzumab

    Directory of Open Access Journals (Sweden)

    Emre Kaynak

    2014-12-01

    Full Text Available Radiation recall phenomenon is an acute, egzematous reaction that develops throughout a previously irradiated area, precipitated by the administration of docetaxel, doxorubicin, gemcitabine and paclitaxel. We report a 52-year-old woman with breast cancer who received locoregional radiotherapy followed by trastuzumab monotherapy. Three day after the first cycle of trastuzumab monotherapy, dermatitis developed in the previously irradiated skin.

  19. Exacerbating factors of itch in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Hiroyuki Murota

    2017-01-01

    Full Text Available Atopic dermatitis (AD displays different clinical symptoms, progress, and response to treatment during early infancy and after childhood. After the childhood period, itch appears first, followed by formation of well-circumscribed plaque or polymorphous dermatoses at the same site. When accompanied with dermatitis and dry skin, treatment of skin lesions should be prioritized. When itch appears first, disease history, such as causes and time of appearance of itch should be obtained by history taking. In many cases, itch increases in the evening when the sympathetic nerve activity decreased. Treatment is provided considering that hypersensitivity to various external stimulations can cause itch. Heat and sweating are thought to especially exacerbate itch. Factors causing itch, such as cytokines and chemical messengers, also induce itch mainly by stimulating the nerve. Scratching further aggravates dermatitis. Skin hypersensibility, where other non-itch senses, such as pain and heat, are felt as itch, sometimes occurs in AD. Abnormal elongation of the sensory nerve into the epidermis, as well as sensitizing of the peripheral/central nerve, are possible causes of hypersensitivity, leading to itch. To control itch induced by environmental factors such as heat, treatment for dermatitis is given priority. In the background of itch exacerbated by sweating, attention should be given to the negative impact of sweat on skin homeostasis due to 1 leaving excess sweat on the skin, and 2 heat retention due to insufficient sweating. Excess sweat on the skin should be properly wiped off, and dermatitis should be controlled so that appropriate amount of sweat can be produced. Not only stimulation from the skin surface, but also visual and auditory stimulation can induce new itch. This “contagious itch” can be notably observed in patients with AD. This article reviews and introduces causes of aggravation of itch and information regarding how to cope with such

  20. Tea tree oil attenuates experimental contact dermatitis.

    Science.gov (United States)

    Wallengren, Joanna

    2011-07-01

    Herbs and minerals have been used in clinical dermatology for hundreds of years and herbal ingredients are becoming increasingly popular with the public in treatment of various dermatological conditions characterised by inflammation and pruritus. The aim of this study was to compare the efficacy of traditional topical therapeutic agents with a moderate potency topical glucocorticoid on experimental contact dermatitis and contact urticaria. The effects of ichthammol 10% pet, zinc oxide 20% pet, camphor 20% pet, levomenthol 10% pet, tea tree oil 20 or 50% and clobetason butyrate 0.05% ointment were studied in the following experimental models: elicitation of allergic contact dermatitis to nickel, irritant contact dermatitis to benzalkonium chloride, and in immediate reactions to histamine and benzoic acid (non-immunological contact utricaria) respectively. Delayed reactions were evaluated using a clinical scoring system and immediate reactions were estimated by planimetry. Histamine-induced pruritus was evaluated using VAS. Tea tree oil reduced allergic contact dermatitis by 40.5% (p = 0.003), zinc oxide by 17.4% (p = 0.04) and clobetason butyrate by 23.5% (p = 0.01). Zinc oxide reduced histamine induced flare by 18.5% (p = 0.01), ichthammol by 19.2% (p = 0.02) and clobetason butyrate by 44.1% (p = 0.02). Irritant contact dermatitis and non-immunological contact urticaria were not influenced by the pre-treatments. Pruritus induced by histamine also remained unchanged. In conclusion, tea tree oil seems to be a more effective anti-eczematic agent than zinc oxide and clobetasone butyrate, while clobetasone butyrate is superior to both ichthammol and zinc oxide in topical treatment of urticarial reactions.

  1. Facial pain and temporomandibular disorders

    OpenAIRE

    2002-01-01

    Abstract The study was undertaken to determine the prevalence of facial pain and the association of facial pain with temporomandibular disorders (TMD) as well as with other factors, in a geographically defined population-based sample consisting of subjects born in 1966 in northern Finland, and in a case-control study including subjects with facial pain and their healthy controls. In addition, the influence of conservative stomatognathic and necessary prosthetic treatme...

  2. [Prosopagnosia and facial expression recognition].

    Science.gov (United States)

    Koyama, Shinichi

    2014-04-01

    This paper reviews clinical neuropsychological studies that have indicated that the recognition of a person's identity and the recognition of facial expressions are processed by different cortical and subcortical areas of the brain. The fusiform gyrus, especially the right fusiform gyrus, plays an important role in the recognition of identity. The superior temporal sulcus, amygdala, and medial frontal cortex play important roles in facial-expression recognition. Both facial recognition and facial-expression recognition are highly intellectual processes that involve several regions of the brain.

  3. Virtual 3-D Facial Reconstruction

    Directory of Open Access Journals (Sweden)

    Martin Paul Evison

    2000-06-01

    Full Text Available Facial reconstructions in archaeology allow empathy with people who lived in the past and enjoy considerable popularity with the public. It is a common misconception that facial reconstruction will produce an exact likeness; a resemblance is the best that can be hoped for. Research at Sheffield University is aimed at the development of a computer system for facial reconstruction that will be accurate, rapid, repeatable, accessible and flexible. This research is described and prototypical 3-D facial reconstructions are presented. Interpolation models simulating obesity, ageing and ethnic affiliation are also described. Some strengths and weaknesses in the models, and their potential for application in archaeology are discussed.

  4. History of facial pain diagnosis

    Science.gov (United States)

    Jensen, Troels S

    2017-01-01

    Premise Facial pain refers to a heterogeneous group of clinically and etiologically different conditions with the common clinical feature of pain in the facial area. Among these conditions, trigeminal neuralgia (TN), persistent idiopathic facial pain, temporomandibular joint pain, and trigeminal autonomic cephalalgias (TAC) are the most well described conditions. Conclusion TN has been known for centuries, and is recognised by its characteristic and almost pathognomonic clinical features. The other facial pain conditions are less well defined, and over the years there has been confusion about their classification. PMID:28181442

  5. Atopic dermatitis and allergic reactions to individual fragrance chemicals.

    Science.gov (United States)

    White, J M L; White, I R; Kimber, I; Basketter, D A; Buckley, D A; McFadden, J P

    2009-02-01

    Allergic contact dermatitis prevalence is reported as equal in atopic and nonatopic dermatitis. Atopic dermatitis is under-represented in those with allergic contact dermatitis to agents having cutaneous and dietary exposure. We compared rates of atopic dermatitis between patients with allergic contact dermatitis arising out of individual fragrance chemicals with known oral/cutaneous exposure against exclusively cutaneous exposure. Between 1982 and 2007, 37 065 dermatitis patients were tested with Fragrance mix I. Those who were positive were tested for individual fragrance allergy. Chemicals were categorized according to whether their exposure pattern was solely cutaneous, oral or mixed. Current and past atopic dermatitis rates were compared between the whole population and groups allergic to individual fragrances. Age and gender were controlled. Cinnamic alcohol and cinnamal allergy groups had reduced rates of both 'current' [24/266 (9.0%) P = 0.0008, 38/364 (10.4%) P = 0.0005] and 'past' atopic dermatitis [44/266 (16.5%) P = 0.009, 70/346 (19.2%) P = 0.037]. Atopic dermatitis rates in groups allergic to Evernia prunastri and hydroxycitronellal (cutaneous exposure only) were not reduced [120/597 (20.1%) and 41/153 (26.8%)]. Groups allergic to cinnamic alcohol (P Evernia prunastri. Patients allergic to individual fragrances with dietary exposure have reduced rates of atopic dermatitis. This suggests that patients with atopic dermatitis have heightened oral tolerance to dietary haptens, in contrast to the known close association of atopic dermatitis with food-protein allergy. Haptens may interfere with food protein tolerance by binding to soluble protein to alter its configuration and immunogenic profile.

  6. Botulinum Toxin (Botox) for Facial Wrinkles

    Science.gov (United States)

    ... Stories Español Eye Health / Eye Health A-Z Botulinum Toxin (Botox) for Facial Wrinkles Sections Botulinum Toxin (Botox) ... Facial Wrinkles How Does Botulinum Toxin (Botox) Work? Botulinum Toxin (Botox) for Facial Wrinkles Written by: Kierstan Boyd ...

  7. Facial nerve palsy due to birth trauma

    Science.gov (United States)

    Seventh cranial nerve palsy due to birth trauma; Facial palsy - birth trauma; Facial palsy - neonate; Facial palsy - infant ... this condition. Some factors that can cause birth trauma (injury) include: Large baby size (may be seen ...

  8. iFace: Facial Expression Training System

    OpenAIRE

    Ito, Kyoko; Kurose, Hiroyuki; Takami, Ai; Nishida, Shogo

    2008-01-01

    In this study, a target facial expression selection interface for a facial expression training system and a facial expression training system were both proposed and developed. Twelve female dentists used the facial expression training system, and evaluations and opinions about the facial expression training system were obtained from these participants. In the future, we will attempt to improve both the target facial expression selection interface and the comparison of a current and a target f...

  9. Cephalometric soft tissue facial analysis.

    Science.gov (United States)

    Bergman, R T

    1999-10-01

    My objective is to present a cephalometric-based facial analysis to correlate with an article that was published previously in the American Journal of Orthodontic and Dentofacial Orthopedics. Eighteen facial or soft tissue traits are discussed in this article. All of them are significant in successful orthodontic outcome, and none of them depend on skeletal landmarks for measurement. Orthodontic analysis most commonly relies on skeletal and dental measurement, placing far less emphasis on facial feature measurement, particularly their relationship to each other. Yet, a thorough examination of the face is critical for understanding the changes in facial appearance that result from orthodontic treatment. A cephalometric approach to facial examination can also benefit the diagnosis and treatment plan. Individual facial traits and their balance with one another should be identified before treatment. Relying solely on skeletal analysis, assuming that the face will balance if the skeletal/dental cephalometric values are normalized, may not yield the desired outcome. Good occlusion does not necessarily mean good facial balance. Orthodontic norms for facial traits can permit their measurement. Further, with a knowledge of standard facial traits and the patient's soft tissue features, an individualized norm can be established for each patient to optimize facial attractiveness. Four questions should be asked regarding each facial trait before treatment: (1) What is the quality and quantity of the trait? (2) How will future growth affect the trait? (3) How will orthodontic tooth movement affect the existing trait (positively or negatively)? (4) How will surgical bone movement to correct the bite affect the trait (positively or negatively)?

  10. A Mouse Model of Anaphylaxis and Atopic Dermatitis to Salt-Soluble Wheat Protein Extract.

    Science.gov (United States)

    Jin, Yining; Ebaugh, Sarah; Martens, Anna; Gao, Haoran; Olson, Eric; Ng, Perry K W; Gangur, Venu

    2017-09-27

    Wheat allergy and other immune-mediated disorders triggered by wheat proteins are growing at an alarming rate for reasons not well understood. A mouse model to study hypersensitivity responses to salt-soluble wheat protein (SSWP) extract is currently unavailable. Here we tested the hypothesis that SSWP extract from wheat will induce sensitization as well as allergic disease in mice. Female BALB/cJ mice were weaned onto a plant protein-free diet. The mice were injected a total of 4 times with an SSWP (0.01 mg/mouse) fraction extracted from durum wheat along with alum as an adjuvant. Blood was collected biweekly and SSWP-specific IgE (SIgE) and total IgE (TIgE) levels were measured using ELISA. Systemic anaphylaxis upon intraperitoneal injection with SSWP was quantified by hypothermia shock response (HSR). Mucosal mast cell degranulation was measured by the elevation of mMCP-1 in the blood. The mice were monitored for dermatitis. Skin tissues were used in histopathology and for measuring cytokine/chemokine/adhesion molecule levels using a protein microarray system. Injection with SSWP resulted in time-dependent SIgE antibody responses associated with the elevation of TIgE concentration. Challenge with SSWP elicited severe HSR that correlated with a significant elevation of plasma mMCP-1 levels. Sensitized mice developed facial dermatitis associated with mast cell degranulation. Lesions expressed significant elevation of Th2/Th17/Th1 cytokines and chemokines and E-selectin adhesion molecule. Here we report a mouse model of anaphylaxis and atopic dermatitis to SSWP extract that may be used for further basic and applied research on wheat allergy. © 2017 S. Karger AG, Basel.

  11. Plastic Changes of Synapses and Excitatory Neurotransmitter Receptors in Facial Nucleus Following Facial-facial Anastomosis

    Institute of Scientific and Technical Information of China (English)

    Pei CHEN; Jun SONG; Linghui LUO; Shusheng GONG

    2008-01-01

    The remodeling process of synapses and eurotransmitter receptors of facial nucleus were observed. Models were set up by facial-facial anastomosis in rat. At post-surgery day (PSD) 0, 7, 21 and 60, synaptophysin (p38), NMDA receptor subunit 2A and AMPA receptor subunit 2 (GIuR2) were observed by immunohistochemical method and emi-quantitative RT-PCR, respectively. Meanwhile, the synaptic structure of the facial motorneurons was observed under a transmission electron microscope (TEM). The intensity of p38 immunoreactivity was decreased, reaching the lowest value at PSD day 7, and then increased slightly at PSD 21. Ultrastructurally, the number of synapses in nucleus of the operational side decreased, which was consistent with the change in P38 immhnoreactivity. NMDAR2A mRNA was down-regulated significantly in facial nucleus after the operation (P000.05). The synapses innervation and the expression of NMDAR2A and AMPAR2 mRNA in facial nucleus might be modified to suit for the new motor tasks following facial-facial anastomosis, and influenced facial nerve regeneration and recovery.

  12. Children's Facial Trustworthiness Judgments: Agreement and Relationship with Facial Attractiveness.

    Science.gov (United States)

    Ma, Fengling; Xu, Fen; Luo, Xianming

    2016-01-01

    This study examined developmental changes in children's abilities to make trustworthiness judgments based on faces and the relationship between a child's perception of trustworthiness and facial attractiveness. One hundred and one 8-, 10-, and 12-year-olds, along with 37 undergraduates, were asked to judge the trustworthiness of 200 faces. Next, they issued facial attractiveness judgments. The results indicated that children made consistent trustworthiness and attractiveness judgments based on facial appearance, but with-adult and within-age agreement levels of facial judgments increased with age. Additionally, the agreement levels of judgments made by girls were higher than those by boys. Furthermore, the relationship between trustworthiness and attractiveness judgments increased with age, and the relationship between two judgments made by girls was closer than those by boys. These findings suggest that face-based trait judgment ability develops throughout childhood and that, like adults, children may use facial attractiveness as a heuristic cue that signals a stranger's trustworthiness.

  13. Clinico-Epidemiological Profile And Factors Affecting Severity Of Atopic Dermatitis In North Indian Chilldren

    Directory of Open Access Journals (Sweden)

    Sarkar Rashmi

    2004-01-01

    Full Text Available Atopic dermatitis (AD is a chronic, relapsing dermatitis commonly affecting children. Various epidemiologic factors and clinical patterns of the same were evaluated in 125 patients out of 418 attending the pediatric dermatology clinic over a period of 11/2 years. Of these, 26 were infants (upto 1 year of age and 99 were children. Mean duration of the disease in the infantile group was 3 months while in the childhood group it was 6 years. In the infantile group, family history of atopy was found in 11 patients (42.3%, while in the childhood group 35 (35.35% had family history of atopy, 7 (7.07% had personal history of atopy and 2 (2.02% had both personal and family history of atopy. The infantile group had more frequent facial involvement and acute type of eczema, while in the childhood type, site involvement was less specific and chronic type of eczema was more frequent. Most of the patients had mild to moderate degree of severity of the disease.

  14. [Rehabilitation of facial paralysis].

    Science.gov (United States)

    Martin, F

    2015-10-01

    Rehabilitation takes an important part in the treatment of facial paralysis, especially when these are severe. It aims to lead the recovery of motor activity and prevent or reduce sequelae like synkinesis or spasms. It is preferable that it be proposed early in order to set up a treatment plan based on the results of the assessment, sometimes coupled with an electromyography. In case of surgery, preoperative work is recommended, especially in case of hypoglossofacial anastomosis or lengthening temporalis myoplasty (LTM). Our proposal is to present an original technique to enhance the sensorimotor loop and the cortical control of movement, especially when using botulinum toxin and after surgery.

  15. One thousand cases of severe occupational contact dermatitis

    DEFF Research Database (Denmark)

    Schwensen, Jakob Ferløv; Friis, Ulrik Fischer; Menné, Torkil;

    2013-01-01

    Background. Occupational contact dermatitis is frequent, and further understanding of the epidemiology will improve the basis of its prevention. Objectives. To identify occupations at risk for severe occupational contact dermatitis. Methods. The last 1000 cases of severe occupational contact...... dermatitis seen at our department were identified. Results. The study population comprised 618 females and 382 males. The mean age at onset of irritant contact dermatitis was significantly lower than the mean age at onset of allergic contact dermatitis for both sexes, irrespective of the presence of atopic....... Occupational contact dermatitis remains frequent, even if only severe cases are considered. It is a concern that no effective, systematic interventions and prevention schemes have been launched in Europe, despite documentation of a significant problem overmany years, and knowledge of risk occupations and risk...

  16. [Contact dermatitis: an approach used by a medical officer].

    Science.gov (United States)

    Vologzhanin, D A; Bozhchenko, A A; Bala, A M

    2012-01-01

    The article deals with contact dermatitis issues, that are of interest not only for dermatologists and specialists in professional pathology, but as well as for general practitioners. Issues of contact dermatitis classification, pathogenic peculiarities of the disease main forms and their basic causes are discussed. Clinical manifestations of irritative and allergic contact dermatitis are described in detail, aspects of differential diagnostics analysed. A detailed consideration is given to allergic diagnostics of contact dermatitis using application test-systems with the most common contact allergens. Main principles of contact dermatitis treatment are outlined in the article. The necessity of a complex approach to this disease therapy that requires not only external therapy, but the compliance with an appropriate treatment regimen, diet as well as application of a particular system therapy is shown. Recommendations for contact dermatitis prophylaxis are given.

  17. Hand eczema, atopic dermatitis and filaggrin mutations in adult Danes

    DEFF Research Database (Denmark)

    Heede, Nina G; Thuesen, Betina H; Thyssen, Jacob P

    2017-01-01

    BACKGROUND: Atopic dermatitis and hand eczema often impair the ability of people to work. Only a few studies have investigated whether individuals with loss-of-function filaggrin gene (FLG) mutations, who often have severe and early onset of dermatitis, experience occupational consequences....... OBJECTIVE: To investigate the personal consequences of having atopic dermatitis and/or hand eczema and FLG mutations. METHOD: Adult Danes from the general population (n = 3247) and patients with atopic dermatitis and/or hand eczema (n = 496) were genotyped for common FLG mutations, and completed...... in the general population, especially among individuals with a history of atopic dermatitis. Moreover, self-reported hand eczema and atopic dermatitis were associated with particularly high risk of disability pension among FLG mutation carriers [odds ratio (OR) 4.02 and 95% confidence interval (CI): 1...

  18. [Clinical symptomps, diagnosis and therapy of feline allergic dermatitis].

    Science.gov (United States)

    Favrot, C; Rostaher, A; Fischer, N

    2014-07-01

    Allergies are often suspected in cats and they are mainly hypersensitivity reactions against insect bites, food- or environmental allergens. Cats, with non flea induced atopic dermatitis, normally present with one oft he following reaction patterns: miliary dermatitis, eosinophilic dermatitis, selfinduced alopecia or head and neck excoriations. None of these reaction patterns is nevertheless pathognomonic for allergic dermatitis, therefore the diagnosis is based on the one hand on the exclusion of similar diseases on the other hand on the successful response on a certain therapy. Recently a study on the clinical presentation of cats with non flea induced atopic dermatitis was published. In this study certain criteria for diagnosing atopy in cats were proposed. For therapy of allergic cats cyclosporin, glucocorticoids, antihistamines, hypoallergenic diets and allergen specific immunotherapy are used. This article should provide a recent overview on the clinical symptoms, diagnosis and therapy of feline allergic dermatitis.

  19. Parthenium dermatitis severity score to assess clinical severity of disease

    OpenAIRE

    Kaushal K Verma; Arika Bansal; Neetu Bhari; Gomathy Sethuraman

    2017-01-01

    Background: Parthenium dermatitis is the most common type of airborne contact dermatitis in India. It is a chronic disease of a remitting and relapsing course with significant morbidity and distress, but there is no scoring system to assess its severity. Aim: To design a scoring system for the assessment of clinical severity of disease in Parthenium dermatitis and to use this scoring system in various studies to determine its sensitivity, specificity, and reproducibility. Methods and Results:...

  20. [Contact Paederus dermatitis in a 12 years old boy].

    Science.gov (United States)

    Pagotto, Betina; Plafnik, Romina; Castillo, Andrea; Cionci, Jimena; Abad, María Eugenia; Cabanilas, María Silvina; Larralde, Margarita

    2013-06-01

    Paederus dermatitis is a peculiar contact dermatitis caused by pederine contained in the hemolimph of a small insect of the genus Paederus. It is characterized by vesico-pustulous eruption arising over an erythematous background, of sudden onset, over exposed areas of the body, and the history of outdoor activities. Diagnosis is based on the typical clinical features and the epidemiological context. The aim of this publication is to report a case and evaluate the epidemiological and clinical characteristics of Paederus dermatitis.

  1. Allergic contact dermatitis from falcarinol isolated from Schefflera arboricola.

    Science.gov (United States)

    Hansen, L; Hammershøy, O; Boll, P M

    1986-02-01

    From the plant Schefflera arboricola, which has been reported to cause allergic contact dermatitis, we have isolated and determined the elicitor of allergic contact dermatitis as falcarinol, heptadeca-1,9(Z)-diene-4,6-diyne-3-ol. Three polyacetylenes closely related to falcarinol, namely falcarindiol, falcarinone and dehydrofalcarinone were tested simultaneously. Falcarinol, but not falcarindiol, falcarinone and dehydrofalcarinone, elicited allergic contact dermatitis in a 38-year-old female plant-nursery worker.

  2. Processing faces and facial expressions.

    Science.gov (United States)

    Posamentier, Mette T; Abdi, Hervé

    2003-09-01

    This paper reviews processing of facial identity and expressions. The issue of independence of these two systems for these tasks has been addressed from different approaches over the past 25 years. More recently, neuroimaging techniques have provided researchers with new tools to investigate how facial information is processed in the brain. First, findings from "traditional" approaches to identity and expression processing are summarized. The review then covers findings from neuroimaging studies on face perception, recognition, and encoding. Processing of the basic facial expressions is detailed in light of behavioral and neuroimaging data. Whereas data from experimental and neuropsychological studies support the existence of two systems, the neuroimaging literature yields a less clear picture because it shows considerable overlap in activation patterns in response to the different face-processing tasks. Further, activation patterns in response to facial expressions support the notion of involved neural substrates for processing different facial expressions.

  3. Tracking facial features with occlusions

    Institute of Scientific and Technical Information of China (English)

    MARKIN Evgeny; PRAKASH Edmond C.

    2006-01-01

    Facial expression recognition consists of determining what kind of emotional content is presented in a human face.The problem presents a complex area for exploration, since it encompasses face acquisition, facial feature tracking, facial expression classification. Facial feature tracking is of the most interest. Active Appearance Model (AAM) enables accurate tracking of facial features in real-time, but lacks occlusions and self-occlusions. In this paper we propose a solution to improve the accuracy of fitting technique. The idea is to include occluded images into AAM training data. We demonstrate the results by running ex periments using gradient descent algorithm for fitting the AAM. Our experiments show that using fitting algorithm with occluded training data improves the fitting quality of the algorithm.

  4. Facial Asymmetry and Emotional Expression

    CERN Document Server

    Pickin, Andrew

    2011-01-01

    This report is about facial asymmetry, its connection to emotional expression, and methods of measuring facial asymmetry in videos of faces. The research was motivated by two factors: firstly, there was a real opportunity to develop a novel measure of asymmetry that required minimal human involvement and that improved on earlier measures in the literature; and secondly, the study of the relationship between facial asymmetry and emotional expression is both interesting in its own right, and important because it can inform neuropsychological theory and answer open questions concerning emotional processing in the brain. The two aims of the research were: first, to develop an automatic frame-by-frame measure of facial asymmetry in videos of faces that improved on previous measures; and second, to use the measure to analyse the relationship between facial asymmetry and emotional expression, and connect our findings with previous research of the relationship.

  5. Vascularization of the facial bones by facial artery: implications for full face allotransplantation

    OpenAIRE

    Rampazzo, Antonio

    2014-01-01

    Background-The maxillary artery is recognized as the main vascular supply of the facial bones; nonetheless clinical evidence supports a co-dominant role for the facial artery. This study explores the extent of the facial skeleton within a facial allograft that can be harvested based on the facial artery. Methods-Twenty-three cadaver heads were used in this study. In 12 heads, the right facial, superficial temporal and maxillary arteries were injected. In 1 head, facial artery angiography w...

  6. Odontogenic Facial Cellulitis

    Directory of Open Access Journals (Sweden)

    Yordany Boza Mejias

    2012-11-01

    Full Text Available Background: odontogenic facial cellulitis is an acute inflammatory process manifested in very different ways, with a variable scale in clinical presentation ranging from harmless well defined processes, to diffuse and progressive that may develop complications leading the patient to a critical condition, even risking their lives. Objective: To characterize the behavior of odontogenic facial cellulitis. Methods: A descriptive case series study was conducted at the dental clinic of Aguada de Pasajeros, Cienfuegos, from September 2010 to March 2011. It included 56 patients who met the inclusion criteria. Variables analyzed included: sex, age, teeth and regions affected, causes of cellulite and prescribed treatment. Results: no sex predilection was observed, lower molars and submandibular anatomical region were the most affected (50% and 30 4% respectively being tooth decay the main cause for this condition (51, 7%. The opening access was not performed to all the patients in the emergency service. The causal tooth extraction was not commonly done early, according to the prescribed antibiotic group. Thermotherapy with warm fomentation and saline mouthwash was the most prescribed and the most widely used group of antibiotics was the penicillin. Conclusions: dental caries were the major cause of odontogenic cellulite. There are still difficulties with the implementation of opening access.

  7. Contact dermatitis due to xanthium strumarium

    Directory of Open Access Journals (Sweden)

    Pasricha J

    1990-01-01

    Full Text Available A 50-year-old mining engineer at Dhanbad was having air bome contact Dermatitis suspected to be caused by Xanthium strumarium. Patch tests with a 15% aqueous extract of air dried leaves showed a severe positive reaction, but the patient also had positive patch tests with Parthenium hysterphorus and a few other weeds and trees known to cause air-borne contact dermatitis. The titre of contact hypersensitivity with the extract of Xanthium struma′rium was more than 1:100,000 and for Parthenium hysterophrous it was 1:10 indicating a high degree of hypersensitivity to Xanthium strumarium. Further tests in 14 other patients revealed a high prevalence of cross sensitivity between these two plants both of which belong to the compositae family.

  8. Contact dermatitis to hair dye: An update

    Directory of Open Access Journals (Sweden)

    Sanjeev Handa

    2012-01-01

    Full Text Available Exposure to hair dyes has long been known as a significant risk factor for development of allergic contact dermatitis among the exposed population as these lead to severe eczema of face and upper trunk in the consumer and hand eczema in hair-dressers. Currently, para-phenylenediamine (PPD is the main ingredient used in permanent hair color products in the market and is the most important allergen. Prevalence of PPD sensitization is high in patients with contact dermatitis across all continents, with hair dye use being the commonest cause. In order to decrease the burden of disease, use of alternative natural dyeing agents among consumers and use of barrier neoprene gloves among hairdressers should be encouraged apart from stringent legislation to reduce the amount of PPD reaching the consumer.

  9. Fingertip dermatitis in a retail florist.

    Science.gov (United States)

    Guin, J D; Franks, H

    2001-04-01

    Prevalence of plant contact dermatitis in retail florists varies with exposure, and the number of reports of contact allergy to cut tulips is rather small. Alpha-methylene-gamma-butyrolactone is better known as the cause of both Alstroemeria dermatitis in retail florists and tulip finger in wholesale floral workers who handle the bulbs. Our patient presented with prominent erythema, scaling, and peeling of the skin of the thumb, index, and middle fingers of his right hand. Results of a patch test to alpha-methylene-gamma-butyrolactone were strongly positive, and the patient determined that the exposure had occurred when he stripped leaves from the tulip stems to arrange cut flowers. Other natural sources of the antigen include Alstroemeria; Bomarea; Dioscorea hispida; Erythronium; Gagea; Fritillaria; and at least one species of onion, Allium triquetrum.

  10. ATOPIC DERMATITIS: NEW TARGETS OF THERAPY

    Directory of Open Access Journals (Sweden)

    D. Sh. Macharadze

    2014-01-01

    Full Text Available Treatment of atopic dermatitis (AD is most often based on the relief of symptoms. Two fundamental basis of AD — dry skin and itching — determine the main objectives of treatment of this chronic inflammatory diseases of the skin. With this purpose, the patients are recommended to use moisturizers (emollients and topical anti-inflammatory drugs — corticosteroids, and/or calcineurin inhibitors. However, there are studies conclusively proving the existence of subclinical inflammation associated with impaired barrier function ofthe skin, production of cytokines and infiltration of lymphocytes. The new strategy of treatment — proactive therapy aimed at achieving control and maintenance of remission of atopic dermatitis. This will allow you to achieve faster control the symptoms of AD and to reduce the risk of recurrence of the disease.

  11. Contact Dermatitis In Automobile Repair workers

    Directory of Open Access Journals (Sweden)

    Joshi M P

    1997-01-01

    Full Text Available Automobile repair workers are at risk of developing skin morbidity including occupational dermatoses because of their exposure to mineral oils, petroleum products and its derivatives and lubricating oil. This cross- sectional study was carried out at Maharashtra State Road Transport Corporation workshops in Nagpur city to investigate prevalence of skin morbidity including contact dermatitis in automobile repair workers. The study included 288 (49.9% automobile repair workers 180 (31.3% workshop office staff and 109 (18.8% divisional office employees. Dermatitis was the commonest skin morbidity in all the study subjects and it was significantly more prevalent in automobile repair workers. Folliculitis was detected in 13.2% of auto â€" repair workers and was not seen in the other two groups. Increasing trend of skin morbidity was correlated with the length of service of employees. Proper protective measures along with suitable washing facilities should be provided

  12. Skin barrier in atopic dermatitis: beyond filaggrin*

    Science.gov (United States)

    Zaniboni, Mariana Colombini; Samorano, Luciana Paula; Orfali, Raquel Leão; Aoki, Valéria

    2016-01-01

    Atopic dermatitis is a chronic inflammatory skin disease with a complex pathogenesis, where changes in skin barrier and imbalance of the immune system are relevant factors. The skin forms a mechanic and immune barrier, regulating water loss from the internal to the external environment, and protecting the individual from external aggressions, such as microorganisms, ultraviolet radiation and physical trauma. Main components of the skin barrier are located in the outer layers of the epidermis (such as filaggrin), the proteins that form the tight junction (TJ) and components of the innate immune system. Recent data involving skin barrier reveal new information regarding its structure and its role in the mechanic-immunological defense; atopic dermatitis (AD) is an example of a disease related to dysfunctions associated with this complex. PMID:27579743

  13. Genetic variation of contact dermatitis in broilers

    DEFF Research Database (Denmark)

    Ask, Birgitte

    2010-01-01

    This study aimed to investigate the presence of genetic variation in footpad dermatitis (FPD) and hock burns (HB) and the possibility to genetically select against these. A field trial including 10 commercial broiler lines (n = 102 to 265) was carried out at 2 Dutch farms. Footpad dermatitis and HB...... to welfare. Genetic variation between and within lines was present for both FPD and HB as indicated by between-line differences and heritabilities, and selection against FPD and HB is, therefore, possible. It is important that selection is done against both FPD and HB, and such selection should not have...... were subjectively scored at ~4, 5, and 7 wk on a scale from 0 through 5. Genetic parameters were estimated in 2 lines based on a larger data set. The overall agreement of repeated FPD and HB scores was high (0.66 to 0.86) and the scoring system was, therefore, considered reliable. Kendall's tau between...

  14. Autoimmune Progesterone Dermatitis: A Case Report

    Directory of Open Access Journals (Sweden)

    Rachana George

    2012-01-01

    Full Text Available Background. Autoimmune progesterone dermatitis is a rare cyclic premenstrual allergic reaction to progesterone produced during the luteal phase of a woman's menstrual cycle. Patients present with a variety of conditions including erythema multiforme, eczema, urticaria, angioedema, and progesterone-induced anaphylaxis. Case. Thirty-eight-year-old woman G2P2002 presents with erythema multiforme and urticarial rash one week prior to her menses starting one year after menarche. She was treated with oral contraceptive pills and the symptoms resolved. Conclusion. This is a typical case of progesterone autoimmunity. The diagnosis is based on cyclic nature of the dermatitis. This differentiates the condition from other allergies or systemic diseases with skin manifestations. Inhibition of ovulation in such cases results in decrease in progesterone secretion and prevention of symptoms.

  15. The survey of cement dermatitis among construction industry workers

    Directory of Open Access Journals (Sweden)

    Faride Sadeghian

    2007-01-01

    Full Text Available Introduction: Cement has long been known as a cause of both irritant and allergic contact dermatitis. However, there are little data relating to occupational skin diseases (OSD in the Iranian construction industry. The aim of this study is to evaluate the epidemiology of cement dermatitis among terrazzo and cement manufactory workers. Methods: This is cross-sectional descriptive study. In this study 50 cement manufact-ory workers in Shahroud and 150 terrazzo workers in Lordegan were interviewed through questionnaire. Questionnaire includes demographic characteristics and questions about present dermatitis, background eczema, daily work hours, exposed chemical agents, using of gloves. Patients examined and patch tested by dermatologist. Data analyzed with SPSS software and c2, Mann Whitney and logistic regression statistical test. Results: The findings of the study showed that 8 workers (16% in cement factories and 52 workers (34.7% in Lordegan terrazzo enterprises had reported dermatitis at the time of review. Of which 15.5% in terrazzo workers had allergic contact dermatitis. In this study the prevalence of cement dermatitis increased with increasing age and there was significantly differences between dermatitis and background of dermatitis in terrazzo workers (P<0.05. Conclusion: Cement should be treated as hazardous materials, wearing of suitable gloves, early diagnosis and treatment of contact dermatitis and health education to workers is suggested.

  16. Allergic contact dermatitis from carvone in hair conditioners.

    Science.gov (United States)

    Quertermous, James; Fowler, Joseph F

    2010-01-01

    Carvone has occasionally been reported as an allergen, usually in flavorings. Isomers of carvone have been either a mint or a rye flavor and aroma. We report a woman with positive patch-test reactions to carvone (newly added to the North American Contact Dermatitis Group standard series) and dermatitis on the head. She had used a hair conditioner with a "mint" scent, and the dermatitis resolved when she discontinued using this product. While the manufacturer would not confirm carvone as an ingredient, the clinical course, patch-test results, and ingredient list strongly suggest that this was a relevant allergen in this case of allergic contact dermatitis.

  17. Mobile Phone Dermatitis in Children and Adults

    DEFF Research Database (Denmark)

    Richardson, Clare; Hamann, Carsten R; Hamann, Dathan

    2014-01-01

    Background: Mobile phones have been reported to cause allergic contact dermatitis (ACD). Methods: A comprehensive online literature review was conducted through the National Library of Medicine (Pubmed MEDLINE) using appropriate medical subject headings and keywords. Results: Thirty-seven cases o....... Metal allergens, notably nickel and chromium, were frequently implicated in mobile phone associated ACD. Nickel release from mobile phones appears to be common and has been reported in both cheap and expensive mobile phones, including phones covered under the EU Nickel Directive....

  18. Dermatitis Kontak Alergi Karena Pemakaian Tato Temporer

    OpenAIRE

    Carolina, Novriwanty; Nababan, Kristo A.; Mahadi, Irma D. Roesyanto

    2010-01-01

    Background: Recently, temporary paint in tattoo has increasingly become popular as safe as alternative permanent tattoos. Allergic contact dermatitis due to paraphenylenediamine (PPD) is frequently among the users of temporary tattoos containing PPD. Case: Reported a case of 34 years old female with erythematous papules, itchy and raised eruption along design of the black tattoo on her lower back that had been done one week earlier. She was cured after the treatment with topical corticoste...

  19. Colesteatoma causando paralisia facial Cholesteatoma causing facial paralysis

    Directory of Open Access Journals (Sweden)

    José Ricardo Gurgel Testa

    2003-10-01

    Full Text Available A paralisia facial causada pelo colesteatoma é pouco freqüente. As porções do nervo mais acometidas são a timpânica e a região do 2º joelho. Nos casos de disseminação da lesão colesteatomatosa para o epitímpano anterior, o gânglio geniculado é o segmento do nervo facial mais sujeito à injúria. A etiopatogenia pode estar ligada à compressão do nervo pelo colesteatoma seguida de diminuição do seu suprimento vascular como também pela possível ação de substâncias neurotóxicas produzidas pela matriz do tumor ou pelas bactérias nele contidas. OBJETIVO: Avaliar a incidência, as características clínicas e o tratamento da paralisia facial decorrente da lesão colesteatomatosa. FORMA DE ESTUDO: Clínico retrospectivo. MATERIAL E MÉTODO: Estudo retrospectivo envolvendo dez casos de paralisia facial por colesteatoma selecionados através de levantamento de 206 descompressões do nervo facial com diferentes etiologias, realizadas na UNIFESP-EPM nos últimos dez anos. RESULTADOS: A incidência de paralisia facial por colesteatoma neste estudo foi de 4,85%,com predominância do sexo feminino (60%. A idade média dos pacientes foi de 39 anos. A duração e o grau da paralisia (inicial juntamente com a extensão da lesão foram importantes em relação à recuperação funcional do nervo facial. CONCLUSÃO: O tratamento cirúrgico precoce é fundamental para que ocorra um resultado funcional mais adequado. Nos casos de ruptura ou intensa fibrose do tecido nervoso, o enxerto de nervo (auricular magno/sural e/ou a anastomose hipoglosso-facial podem ser sugeridas.Facial paralysis caused by cholesteatoma is uncommon. The portions most frequently involved are horizontal (tympanic and second genu segments. When cholesteatomas extend over the anterior epitympanic space, the facial nerve is placed in jeopardy in the region of the geniculate ganglion. The aetiology can be related to compression of the nerve followed by impairment of its

  20. Allergic contact dermatitis in patients with atopic dermatitis: A clinical study

    Directory of Open Access Journals (Sweden)

    Sharma A

    2005-03-01

    Full Text Available BACKGROUND: Atopic dermatitis (AD is a chronically relapsing dermatitis with no known cure. Due to the chronic nature of the condition, frequent and long term topical therapy is used. This may lead to sensitization, resulting in allergic contact dermatitis (ACD. AIMS: The aim of the study was to observe the frequency of ACD in atopic patients in this part of the country using Indian standard battery. METHODS: A total number of 30 cases of AD were taken for the study. Diagnosis of AD cases was based on the criteria of Hannifin and Rajka (1980. All the selected cases of AD had mild to moderate grade of severity. All these cases were treated and patch tested during the remission period. The duration of the study was 12 months. RESULTS: Out of the 30 AD cases, 7 cases showed positive ACD with patch test allergens. CONCLUSION: This study shows that ACD is not uncommon amongst atopic individuals.

  1. MRI of the facial nerve in idiopathic facial palsy

    Energy Technology Data Exchange (ETDEWEB)

    Saatci, I. [Dept. of Radiology, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey); Sahintuerk, F. [Dept. of Radiology, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey); Sennaroglu, L. [Dept. of Otolaryngology, Head and Neck Surgery, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey); Boyvat, F. [Dept. of Radiology, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey); Guersel, B. [Dept. of Otolaryngology, Head and Neck Surgery, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey); Besim, A. [Dept. of Radiology, Hacettepe Univ., Hospital Sihhiye, Ankara (Turkey)

    1996-10-01

    The purpose of this prospective study was to define the enhancement pattern of the facial nerve in idiopathic facial paralysis (Bell`s palsy) on magnetic resonance (MR) imaging with routine doses of gadolinium-DTPA (0.1 mmol/kg). Using 0.5 T imager, 24 patients were examined with a mean interval time of 13.7 days between the onset of symptoms and the MR examination. Contralateral asymptomatic facial nerves constituted the control group and five of the normal facial nerves (20.8%) showed enhancement confined to the geniculate ganglion. Hence, contrast enhancement limited to the geniculate ganglion in the abnormal facial nerve (3 of 24) was referred to a equivocal. Not encountered in any of the normal facial nerves, enhancement of other segments alone or associated with geniculate ganglion enhancement was considered to be abnormal and noted in 70.8% of the symptomatic facial nerves. The most frequently enhancing segments were the geniculate ganglion and the distal intracanalicular segment. (orig.)

  2. New Developments in Biomarkers for Atopic Dermatitis

    Directory of Open Access Journals (Sweden)

    Judith L. Thijs

    2015-03-01

    Full Text Available The application of biomarkers in medicine is evolving. Biomarkers do not only give us a better understanding of pathogenesis, but also increase treatment efficacy and safety, further enabling more precise clinical care. This paper focuses on the current use of biomarkers in atopic dermatitis, new developments and future perspectives. Biomarkers can be used for many different purposes, including the objective determination of disease severity, confirmation of clinical diagnosis, and to predict response to treatment. In atopic dermatitis, many biomarkers have been investigated as a marker for disease severity. Currently serum thymus and activation-regulated chemokine (TARC is the superior biomarker for assessing disease severity. However, we have recently shown that the use of a panel of serum biomarkers is more suitable for assessing disease severity than an individual biomarker. In this overview, we will discuss alternative sources for biomarkers, such as saliva and capillary blood, which can increase the user friendliness of biomarkers in atopic dermatitis (AD. Both methods offer simple, non-invasive and cost effective alternatives to venous blood. This provides great translational and clinical potential. Biomarkers will play an increasingly important role in AD research and personalized medicine. The use of biomarkers will enhance the efficacy of AD treatment by facilitating the individualization of therapy targeting the patients’ specific biological signature and also by providing tools for predicting and monitoring of therapeutic response.

  3. Occupational contact allergic dermatitis in dentistry

    Directory of Open Access Journals (Sweden)

    Mikov Ivan

    2011-01-01

    Full Text Available Introduction. Dental professionals may be at increased risk of developing occupational allergic diseases specially to methacrylates that can permeate protective disposable gloves. Case report. We presented a case of occupational allergic contact dermatitis in a 28-year-old dental technician. The patient had complained of itching and cracking of fingers for 6 months. The dermatitis improved over weekends. Skin erythema and scaling were present with primarily involvement of the fingertips. Patch testing with dental series gave positive vesicular reaction to methyl methacrylate. Follow-up after 6 months of allergen avoidance showed a complete regression of dermatitis. Conclusion. Methacrylates serve as bases for acrylic resins which are used in prosthetics. Methyl methacrylate as a small molecular acrylate can permeate thin protective disposable gloves. Using adequate personal protective equipment, like nitrile rubber gloves, is the most important preventive measure in this occupation. Health practitioners should recognize possible occupational hazards in dentistry and implement appropriate preventive measures to protect health of workers.

  4. The Facial Profile in the Context of Facial Aesthetics.

    Science.gov (United States)

    Heppt, Werner J; Vent, Julia

    2015-10-01

    Beauty has been an intriguing issue since the evolving of a culture in mankind. Even the Neanderthals are believed to have applied makeover to enhance facial structures and thus underline beauty. The determinants of beauty and aesthetics have been defined by artists and scientists alike. This article will give an overview of the evolvement of a beauty concept and the significance of the facial profile. It aims at sharpening the senses of the facial plastic surgeon for analyzing the patient's face, consulting the patient on feasible options, planning, and conducting surgery in the most individualized way.

  5. Diplegia facial traumatica Traumatic facial diplegia: a case report

    Directory of Open Access Journals (Sweden)

    J. Fortes-Rego

    1975-12-01

    Full Text Available É relatado um caso de paralisia facial bilateral, incompleta, associada a hipoacusia esquerda, após traumatismo cranioencefálico, com fraturas evidenciadas radiológicamente. Algumas considerações são formuladas tentando relacionar ditas manifestações com fraturas do osso temporal.A case of traumatic facial diplegia with left partial loss of hearing following head injury is reported. X-rays showed fractures on the occipital and left temporal bones. A review of traumatic facial paralysis is made.

  6. Paralisia facial bilateral Bilateral facial paralysis: a case report

    Directory of Open Access Journals (Sweden)

    J. Fortes-Rego

    1976-03-01

    Full Text Available É apresentado um caso de diplegia facial surgida após meningite meningocócica e infecção por herpes simples. Depois de discutir as diversas condições que o fenômeno pode apresentar-se, o autor inclina-se por uma etiologia herpética.A case of bilateral facial paralysis following meningococcal meningitis and herpes simplex infection is reported. The author discusses the differential diagnosis of bilateral facial nerve paralysis which includes several diseases and syndromes and concludes by herpetic aetiology.

  7. Case for diagnosis. Infective dermatitis associated with HTLV-1: differential diagnosis of atopic dermatitis.

    Science.gov (United States)

    Oliveira, Lorena Maria Lima de; Souza, Marcos Vilela de; Guedes, Antonio Carlos Martins; Araújo, Marcelo Grossi

    2017-01-01

    Infective dermatitis associated with HTLV-1 (IDH) is the main cutaneous marker of HTLV-1 infection. This disease occurs primarily in children and should be differentiated from other eczemas, especially from atopic dermatitis. The largest series of IDH are from Jamaica and Brazil. There are an estimated 15 to 20 million infected people in the world, and Brazil is one of the endemic regions. Studies suggest that IDH in children may be a marker for the development of T-cell leukemia/lymphoma (ATL) or myelopathy associated with HTLV-1/tropical spastic paraparesis (HAM / TSP) in adulthood.

  8. The Dehiscent Facial Nerve Canal

    Directory of Open Access Journals (Sweden)

    Sertac Yetiser

    2012-01-01

    Full Text Available Accidental injury to the facial nerve where the bony canal defects are present may result with facial nerve dysfunction during otological surgery. Therefore, it is critical to know the incidence and the type of facial nerve dehiscences in the presence of normal development of the facial canal. The aim of this study is to review the site and the type of such bony defects in 144 patients operated for facial paralysis, myringoplasty, stapedotomy, middle ear exploration for sudden hearing loss, and so forth, other than chronic suppurative otitis media with or without cholesteatoma, middle ear tumors, and anomaly. Correlation of intraoperative findings with preoperative computerized tomography was also analyzed in 35 patients. Conclusively, one out of every 10 surgical cases may have dehiscence of the facial canal which has to be always borne in mind during surgical manipulation of the middle ear. Computerized tomography has some limitations to evaluate the dehiscent facial canal due to high false negative and positive rates.

  9. Does facial resemblance enhance cooperation?

    Directory of Open Access Journals (Sweden)

    Trang Giang

    Full Text Available Facial self-resemblance has been proposed to serve as a kinship cue that facilitates cooperation between kin. In the present study, facial resemblance was manipulated by morphing stimulus faces with the participants' own faces or control faces (resulting in self-resemblant or other-resemblant composite faces. A norming study showed that the perceived degree of kinship was higher for the participants and the self-resemblant composite faces than for actual first-degree relatives. Effects of facial self-resemblance on trust and cooperation were tested in a paradigm that has proven to be sensitive to facial trustworthiness, facial likability, and facial expression. First, participants played a cooperation game in which the composite faces were shown. Then, likability ratings were assessed. In a source memory test, participants were required to identify old and new faces, and were asked to remember whether the faces belonged to cooperators or cheaters in the cooperation game. Old-new recognition was enhanced for self-resemblant faces in comparison to other-resemblant faces. However, facial self-resemblance had no effects on the degree of cooperation in the cooperation game, on the emotional evaluation of the faces as reflected in the likability judgments, and on the expectation that a face belonged to a cooperator rather than to a cheater. Therefore, the present results are clearly inconsistent with the assumption of an evolved kin recognition module built into the human face recognition system.

  10. Analysis methods for facial motion

    Directory of Open Access Journals (Sweden)

    Katsuaki Mishima

    2009-05-01

    Full Text Available Objective techniques to evaluate a facial movement are indispensable for the contemporary treatment of patients with motor disorders such as facial paralysis, cleft lip, postoperative head and neck cancer, and so on. Recently, computer-assisted, video-based techniques have been devised and reported as measuring systems in which facial movements can be evaluated quantitatively. Commercially available motion analysis systems, in which a stereo-measuring technique with multiple cameras and markers to facilitate search of matching among images through all cameras, also are utilized, and are used in many measuring systems such as video-based systems. The key is how the problems of facial movement can be extracted precisely, and how useful information for the diagnosis and decision-making process can be derived from analyses of facial movement. Therefore, it is important to discuss which facial animations should be examined, and whether fixation of the head and markers attached to the face can hamper natural facial movement.

  11. Acupuncture Treatment of Facial Spasm

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    @@ Case History Ms. Zheng from Singapore, aged 51 years, paid her first visit on Aug.30, 2006, with the chief complaint of left facial paralysis accompanied with facial spasm for 5 years. The patient got left facial paralysis in 2001, which was not completely cured, and developed into facial spasm one year later. Although she had received various treatments including surgical operation, the disease was not cured. At the moment she had discomfort and dull sensation in the left facial area, mainly accompanied with twitching of the peripheral nerve of the eye. She was also accompanied with posterior auricular muscle tension and discomfort. She had fairly good sleep and appetite, but slightly quick temper. Physical examination at the moment showed that the patient had a slightly thin body figure, flushing face, and good mental state. The blood pressure was 110/75mmHg and the heart rate was 85 beats/min. No abnormal signs were found in the heart and lungs. The facial examination showed mild swelling of the left side of the face, incomplete closing of the eye lids, disappearance of wrinkles on the forehead, shallow nasolabial groove, and obvious muscle tension and tenderness in the left opisthotic region. Careful observation could find slight facial muscular twitching. The tongue proper was red with little coating, and the pulse thready-wiry.

  12. Facial Action Units Recognition: A Comparative Study

    NARCIS (Netherlands)

    Popa, M.C.; Rothkrantz, L.J.M.; Wiggers, P.; Braspenning, R.A.C.; Shan, C.

    2011-01-01

    Many approaches to facial expression recognition focus on assessing the six basic emotions (anger, disgust, happiness, fear, sadness, and surprise). Real-life situations proved to produce many more subtle facial expressions. A reliable way of analyzing the facial behavior is the Facial Action Coding

  13. Microbial biofilms on silicone facial prostheses

    NARCIS (Netherlands)

    Ariani, Nina

    2015-01-01

    Facial disfigurements can result from oncologic surgery, trauma and congenital deformities. These disfigurements can be rehabilitated with facial prostheses. Facial prostheses are usually made of silicones. A problem of facial prostheses is that microorganisms can colonize their surface. It is hard

  14. Improving outcomes in aesthetic facial reconstruction.

    Science.gov (United States)

    Hofer, Stefan O P; Mureau, Marc A M

    2009-07-01

    Aesthetic facial reconstruction is a challenging art. Improving outcomes in aesthetic facial reconstruction requires a thorough understanding of the basic principles of the functional and aesthetic requirements for facial reconstruction. From there, further refinement and attention to detail can be provided. This paper discusses basic principles of aesthetic facial reconstruction.

  15. Facial Action Units Recognition: A Comparative Study

    NARCIS (Netherlands)

    Popa, M.C.; Rothkrantz, L.J.M.; Wiggers, P.; Braspenning, R.A.C.; Shan, C.

    2011-01-01

    Many approaches to facial expression recognition focus on assessing the six basic emotions (anger, disgust, happiness, fear, sadness, and surprise). Real-life situations proved to produce many more subtle facial expressions. A reliable way of analyzing the facial behavior is the Facial Action Coding

  16. Facial melanoses: Indian perspective

    Directory of Open Access Journals (Sweden)

    Neena Khanna

    2011-01-01

    Full Text Available Facial melanoses (FM are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma, Riehl′s melanosis, Lichen planus pigmentosus, erythema dyschromicum perstans (EDP, erythrosis, and poikiloderma of Civatte. But there is considerable overlap in features amongst the clinical entities. Etiology in most of the causes is unknown, but some factors such as UV radiation in melasma, exposure to chemicals in EDP, exposure to allergens in Riehl′s melanosis are implicated. Diagnosis is generally based on clinical features. The treatment of FM includes removal of aggravating factors, vigorous photoprotection, and some form of active pigment reduction either with topical agents or physical modes of treatment. Topical agents include hydroquinone (HQ, which is the most commonly used agent, often in combination with retinoic acid, corticosteroids, azelaic acid, kojic acid, and glycolic acid. Chemical peels are important modalities of physical therapy, other forms include lasers and dermabrasion.

  17. Cradle Cap (For Parents)

    Science.gov (United States)

    ... Kids to Be Smart About Social Media Cradle Cap (Infantile Seborrheic Dermatitis) KidsHealth > For Parents > Cradle Cap ( ... many babies develop called cradle cap. About Cradle Cap Cradle cap is the common term for seborrheic ...

  18. Simple technique for facial dimple

    Directory of Open Access Journals (Sweden)

    Ahmed Hassan El-Sabbagh

    2015-01-01

    Full Text Available Background: Subjects seeking aesthetic surgery for facial dimples are increasing in number. Literature on dimple creation surgery are sparse. Various techniques have been used with their own merits and disadvantages. Materials and Methods: Facial dimples were created in 23 cases. All the subjects were females. Five cases were bilateral and the rest were unilateral. Results: Minor complications such as swelling and hematoma were observed in four cases. Infection occurred in two cases. Most of the subjects were satisfied with the results. Conclusions: Suturing technique is safe, reliable and an easily reproducible way to create facial dimple. Level of Evidence: IV: Case series.

  19. Sleep Wrinkles: Facial Aging and Facial Distortion During Sleep.

    Science.gov (United States)

    Anson, Goesel; Kane, Michael A C; Lambros, Val

    2016-09-01

    Wrinkles are just one indicator of facial aging, but an indicator that is of prime importance in our world of facial aesthetics. Wrinkles occur where fault lines develop in aging skin. Those fault lines may be due to skin distortion resulting from facial expression or may be due to skin distortion from mechanical compression during sleep. Expression wrinkles and sleep wrinkles differ in etiology, location, and anatomical pattern. Compression, shear, and stress forces act on the face in lateral or prone sleep positions. We review the literature relating to the development of wrinkles and the biomechanical changes that occur in response to intrinsic and extrinsic influences. We explore the possibility that compression during sleep not only results in wrinkles but may also contribute to facial skin expansion.

  20. Dynamic Facial Prosthetics for Sufferers of Facial Paralysis

    Directory of Open Access Journals (Sweden)

    Fergal Coulter

    2011-10-01

    Full Text Available BackgroundThis paper discusses the various methods and the materialsfor the fabrication of active artificial facial muscles. Theprimary use for these will be the reanimation of paralysedor atrophied muscles in sufferers of non-recoverableunilateral facial paralysis.MethodThe prosthetic solution described in this paper is based onsensing muscle motion of the contralateral healthy musclesand replicating that motion across a patient’s paralysed sideof the face, via solid state and thin film actuators. Thedevelopment of this facial prosthetic device focused onrecreating a varying intensity smile, with emphasis ontiming, displacement and the appearance of the wrinklesand folds that commonly appear around the nose and eyesduring the expression.An animatronic face was constructed with actuations beingmade to a silicone representation musculature, usingmultiple shape-memory alloy cascades. Alongside theartificial muscle physical prototype, a facial expressionrecognition software system was constructed. This formsthe basis of an automated calibration and reconfigurationsystem for the artificial muscles following implantation, soas to suit the implantee’s unique physiognomy.ResultsAn animatronic model face with silicone musculature wasdesigned and built to evaluate the performance of ShapeMemory Alloy artificial muscles, their power controlcircuitry and software control systems. A dual facial motionsensing system was designed to allow real time control overmodel – a piezoresistive flex sensor to measure physicalmotion, and a computer vision system to evaluate real toartificial muscle performance.Analysis of various facial expressions in real subjects wasmade, which give useful data upon which to base thesystems parameter limits.ConclusionThe system performed well, and the various strengths andshortcomings of the materials and methods are reviewedand considered for the next research phase, when newpolymer based artificial muscles are constructed

  1. Prevalence of atopic dermatitis, asthma, allergic rhinitis, and hand and contact dermatitis in adolescents. The Odense Adolescence Cohort Study on Atopic Diseases and Dermatitis

    DEFF Research Database (Denmark)

    Mørtz, Charlotte G; Lauritsen, J M; Bindslev-Jensen, C

    2001-01-01

    BACKGROUND: Atopic diseases are common in children and adolescents. However, epidemiological knowledge is sparse for hand eczema and allergic contact dermatitis in this age group. Furthermore, no population-based studies have evaluated the prevalence of atopic diseases and hand and contact...... or past allergic contact dermatitis was found in 7.2% (girls 11.3% vs. boys 2.5%). Contact allergy was most common to nickel (8.6%) and fragrance mix (1.8%). CONCLUSIONS: High prevalence figures were found for atopic diseases, hand eczema and allergic contact dermatitis, and the diseases were closely...

  2. Pediatric facial burns: Is facial transplantation the new reconstructive psychosurgery?

    Science.gov (United States)

    Hanson, Mark D; Zuker, Ronald M; Shaul, Randi Zlotnik

    2008-01-01

    INTRODUCTION: Current pediatric burn care has resulted in survival being the expectation for most children. Composite tissue allotransplantation in the form of face or hand transplantation may present opportunities for reconstructive surgery of patients with burns. The present paper addresses the question “Could facial transplantation be of therapeutic benefit in the treatment of pediatric burns associated with facial disfigurement?” METHODS: Therapeutic benefit of facial transplantation was defined in terms of psychiatric adjustment and quality of life (QOL). To ascertain therapeutic benefit, studies of pediatric burn injury and associated psychiatric adjustment and QOL in children, adolescents and adults with pediatric burns, were reviewed. RESULTS: Pediatric burn injury is associated with anxiety disorders, including post-traumatic stress disorder and depressive disorders. Many patients with pediatric burns do not routinely access psychiatric care for these disorders, including those for psychiatric assessment of suicidal risk. A range of QOL outcomes were reported; four were predominantly satisfactory and one was predominantly unsatisfactory. DISCUSSION: Facial transplantation may reduce the risk of depressive and anxiety disorders other than post-traumatic stress disorder. Facial transplantation promises to be the new reconstructive psychosurgery, because it may be a surgical intervention with the potential to reduce the psychiatric suffering associated with pediatric burns. Furthermore, patients with pediatric burns may experience the stigma of disfigurement and psychiatric conditions. The potential for improved appearance with facial transplantation may reduce this ‘dual stigmata’. Studies combining surgical and psychiatric research are warranted. PMID:19949498

  3. Allergic contact dermatitis from ethylhexyl salicylate and other salicylates

    DEFF Research Database (Denmark)

    Mortz, Charlotte G; Thormann, Henrik; Goossens, An;

    2010-01-01

    Allergic contact dermatitis (ACD) from salicylates present in topical products is uncommon. Most publications about ACD from salicylates are case reports describing only a few patients. Cross-reactivity between salicylates is not commonly reported. This article describes allergic contact dermatitis...... from ethylhexyl salicylate used as an ultraviolet filter and fragrance compound and reviews the published literature on contact allergy to salicylates....

  4. The course of life of patients with Childhood Atopic Dermatitis

    NARCIS (Netherlands)

    E.E.A. Brenninkmeijer; C.M. Legierse; J.H. Sillevis Smitt; B.F. Last; M.A. Grootenhuis; J.D. Bos

    2009-01-01

    Atopic dermatitis mainly covers the period of infancy to adulthood, an important period in the development of an individual. The impairment of quality of life and the psychological wellbeing of children with atopic dermatitis have been well documented but so far no data exist about the impact of ato

  5. Prevention and treatment of incontinence-associated dermatitis: literature review.

    NARCIS (Netherlands)

    Beeckman, D.; Schoonhoven, L.J.; Verhaeghe, S.; Heyneman, A.; Defloor, T.

    2009-01-01

    AIM: This paper is a report of a review conducted to describe the current evidence about the prevention and treatment of incontinence-associated dermatitis and to formulate recommendations for clinical practice and research. BACKGROUND: Incontinence-associated dermatitis is a common problem in

  6. Methyldibromoglutaronitrile in rinse-off products causes allergic contact dermatitis

    DEFF Research Database (Denmark)

    Jensen, Charlotte Devantier; Johansen, Jeanne Duus; Menné, T

    2004-01-01

    BACKGROUND: The frequency of sensitivity to the cosmetic preservative methyldibromoglutaronitrile (MDBGN) has increased significantly in Europe. Most cases of allergic contact dermatitis from MDBGN are caused by leave-on cosmetic products. The risk of developing allergic contact dermatitis from r...

  7. Work-related hand dermatitis : epidemiological studies in occupational dermatology

    NARCIS (Netherlands)

    Smit, Henriette Anita

    1993-01-01

    Hand eczema or hand dermatitis is a well-known problem in occupations with regular exposure to water and irritating agents ("wet work"). It is experienced frequently by nurses, hairdressers, housewives, food handlers and metal workers. Although hand dermatitis is a relatively infrequent cause of

  8. Work-related hand dermatitis epiemiological studies in occupational dermatology

    NARCIS (Netherlands)

    Smit, H.A.

    1993-01-01

    Hand eczema or hand dermatitis is a well-known problem in occupations with regular exposure to water and irritating agents ("wet work"). It is experienced frequently by nurses, hairdressers, housewives, food handlers and metal workers. Although hand dermatitis is a relatively infrequent cause of

  9. Investigations on the immunopathogenesis of atopic dermatitis in cats

    NARCIS (Netherlands)

    Roosje, Pieternella Janna

    2002-01-01

    The term atopic dermatitis (AD) is commonly used in cats. At present, however, there is little known about the pathogenesis of feline AD. The aim was to investigate various aspects of the immunopathogenesis in a defined group of cats with signs and symptoms of atopic dermatitis and compare our findi

  10. Irritant nail dermatitis of chemical depilatory product presenting with koilonychia.

    Science.gov (United States)

    Pancar, Gunseli Sefika; Kalkan, Goknur

    2014-03-01

    Chemical hair removal products are available as creams, gels, powders, aerosols and roll-ons and all of these forms work in the same way by breaking chemical bonds between sulfur atoms in the protein. Currently, the common active ingredients of these products are calcium thioglycolate, potassium thioglycolate, arsenic and sulfur minerals. Sulfur and arsenic containing products are important toxic chemicals which are mainly used for removing hair in developing countries. Irritant contact dermatitis accounts for 80% of all contact dermatitis reactions which are often occupation-related. Toluene sulfonamide, formaldehyde resin, acrylates and ethylcyanoacrylate are the most common irritants. Irritant nail dermatitis with plants has been well defined with Lobelia richardii flower, Compositae family and garlic. Although allergic dermatitis, irritant dermatitis and irritant nail dermatitis have been well demonstrated with chemicals, koilonychia is unusual presentation of irritant dermatitis. Here we describe a case of nail irritant dermatitis due to application of chemical depilatory product for hair removal presented with koilonychias. To our knowledge this is the first case of such presentation with koilonychia in the English literature.

  11. Topical treatment of contact dermatitis by pine processionary caterpillar

    Science.gov (United States)

    Cuevas, Pedro; Angulo, Javier; Giménez-Gallego, Guillermo

    2011-01-01

    Skin contact dermatitis by pine processionary (Thaumetopoea pityocampa) is a public health problem of increasing significance. The authors present here the case of a 65-year-old man who was diagnosed with processionary caterpillar dermatitis. Patient was treated with topical potassium dobesilate 5% cream twice a day for 2 days. An improvement occurred soon after treatment. PMID:22688482

  12. Host and environmental contribution to atopic dermatitis in dogs

    NARCIS (Netherlands)

    Looringh van Beeck, F.A.

    2014-01-01

    The research presented in this thesis is focussed on atopic dermatitis in dogs. Atopic dermatitis is a genetically predisposed, inflammatory and pruritic allergic skin disease with characteristic clinical features associated with IgE antibodies most commonly directed against environmental allergens.

  13. Allergic Contact Dermatitis to Benzoyl Peroxide Resembling Impetigo.

    Science.gov (United States)

    Kim, Changhyun; Craiglow, Brittany G; Watsky, Kalman L; Antaya, Richard J

    2015-01-01

    A 17-year-old boy presented with recurring severe dermatitis of the face of 5-months duration that resembled impetigo. He had been treated with several courses of antibiotics without improvement. Biopsy showed changes consistent with allergic contact dermatitis and patch testing later revealed sensitization to benzoyl peroxide, which the patient had been using for the treatment of acne vulgaris.

  14. Investigations on the immunopathogenesis of atopic dermatitis in cats

    NARCIS (Netherlands)

    Roosje, Pieternella Janna

    2002-01-01

    The term atopic dermatitis (AD) is commonly used in cats. At present, however, there is little known about the pathogenesis of feline AD. The aim was to investigate various aspects of the immunopathogenesis in a defined group of cats with signs and symptoms of atopic dermatitis and compare our

  15. Investigations on the immunopathogenesis of atopic dermatitis in cats

    NARCIS (Netherlands)

    Roosje, Pieternella Janna

    2003-01-01

    The term atopic dermatitis (AD) is commonly used in cats. At present, however, there is little known about the pathogenesis of feline AD. The aim was to investigate various aspects of the immunopathogenesis in a defined group of cats with signs and symptoms of atopic dermatitis and compare our findi

  16. A Case of Apparent Contact Dermatitis Caused by Toxocara Infection

    Directory of Open Access Journals (Sweden)

    Rosanna Qualizza

    2014-01-01

    Full Text Available Infection from Toxocara species may give rise to a large array of clinical symptoms, including apparent manifestations of allergy such as asthma, urticaria/angioedema, and dermatitis. We report a case, thus far not described, of contact dermatitis attributed to nickel allergy but caused by Toxocara infection. The patient was a 53-year-old woman presenting from 10 years a dermatitis affecting head, neck, and thorax. Patch tests initially performed gave a positive result to nickel, but avoidance of contact with nickel did not result in recovery. The patient referred to our Allergy Service in 2010 because of dermatitis to feet. Patch testing confirmed the positive result for nickel, but expanding the investigation a positive result for IgG antibodies to Toxocara was detected by Western blotting and ELISA. Treatment with mebendazole achieved immediate efficacy on feet dermatitis. Then, two courses of treatment with albendazole resulted in complete regression of dermatitis accompanied by development of negative ELISA and Western blotting for Toxocara antibodies. This report adds another misleading presentation of Toxocara infection as apparent contact dermatitis caused by nickel and suggests bearing in mind, in cases of contact dermatitis not responding to avoidance of the responsible hapten and to medical treatment, the possible causative role of Toxocara.

  17. Nablus mask-like facial syndrome

    DEFF Research Database (Denmark)

    Allanson, Judith; Smith, Amanda; Hare, Heather

    2012-01-01

    Nablus mask-like facial syndrome (NMLFS) has many distinctive phenotypic features, particularly tight glistening skin with reduced facial expression, blepharophimosis, telecanthus, bulky nasal tip, abnormal external ear architecture, upswept frontal hairline, and sparse eyebrows. Over the last few...... heterozygous deletions significantly overlapping the region associated with NMLFS. Notably, while one mother and child were said to have mild tightening of facial skin, none of these individuals exhibited reduced facial expression or the classical facial phenotype of NMLFS. These findings indicate...

  18. Facial Expression Recognition Using SVM Classifier

    OpenAIRE

    2015-01-01

    Facial feature tracking and facial actions recognition from image sequence attracted great attention in computer vision field. Computational facial expression analysis is a challenging research topic in computer vision. It is required by many applications such as human-computer interaction, computer graphic animation and automatic facial expression recognition. In recent years, plenty of computer vision techniques have been developed to track or recognize the facial activities in three levels...

  19. Sympathicotomy for isolated facial blushing

    DEFF Research Database (Denmark)

    Licht, Peter Bjørn; Pilegaard, Hans K; Ladegaard, Lars

    2012-01-01

    Background. Facial blushing is one of the most peculiar of human expressions. The pathophysiology is unclear, and the prevalence is unknown. Thoracoscopic sympathectomy may cure the symptom and is increasingly used in patients with isolated facial blushing. The evidence base for the optimal level...... of targeting the sympathetic chain is limited to retrospective case studies. We present a randomized clinical trial. Methods. 100 patients were randomized (web-based, single-blinded) to rib-oriented (R2 or R2-R3) sympathicotomy for isolated facial blushing at two university hospitals during a 6-year period...... in all social and mental domains in both groups. Overall, 85% of the patients had an excellent or satisfactory result, with no significant difference between the R2 procedure and the R2-R3 procedure. Mild recurrence of facial blushing occurred in 30% of patients within the first year. One patient...

  20. Facial nerve paralysis in children.

    Science.gov (United States)

    Ciorba, Andrea; Corazzi, Virginia; Conz, Veronica; Bianchini, Chiara; Aimoni, Claudia

    2015-12-16

    Facial nerve palsy is a condition with several implications, particularly when occurring in childhood. It represents a serious clinical problem as it causes significant concerns in doctors because of its etiology, its treatment options and its outcome, as well as in little patients and their parents, because of functional and aesthetic outcomes. There are several described causes of facial nerve paralysis in children, as it can be congenital (due to delivery traumas and genetic or malformative diseases) or acquired (due to infective, inflammatory, neoplastic, traumatic or iatrogenic causes). Nonetheless, in approximately 40%-75% of the cases, the cause of unilateral facial paralysis still remains idiopathic. A careful diagnostic workout and differential diagnosis are particularly recommended in case of pediatric facial nerve palsy, in order to establish the most appropriate treatment, as the therapeutic approach differs in relation to the etiology.

  1. Spontaneous Emotional Facial Expression Detection

    Directory of Open Access Journals (Sweden)

    Zhihong Zeng

    2006-08-01

    Full Text Available Change in a speaker’s emotion is a fundamental component in human communication. Automatic recognition of spontaneous emotion would significantly impact human-computer interaction and emotion-related studies in education, psychology and psychiatry. In this paper, we explore methods for detecting emotional facial expressions occurring in a realistic human conversation setting—the Adult Attachment Interview (AAI. Because non-emotional facial expressions have no distinct description and are expensive to model, we treat emotional facial expression detection as a one- class classification problem, which is to describe target objects (i.e., emotional facial expressions and distinguish them from outliers (i.e., non-emotional ones. Our preliminary experiments on AAI data suggest that one-class classification methods can reach a good balance between cost (labeling and computing and recognition performance by avoiding non-emotional expression labeling and modeling.

  2. Imaging of the facial nerve

    Energy Technology Data Exchange (ETDEWEB)

    Veillon, F. [Service de Radiologie I, Hopital de Hautepierre, 67098 Strasbourg Cedex (France)], E-mail: Francis.Veillon@chru-strasbourg.fr; Ramos-Taboada, L.; Abu-Eid, M. [Service de Radiologie I, Hopital de Hautepierre, 67098 Strasbourg Cedex (France); Charpiot, A. [Service d' ORL, Hopital de Hautepierre, 67098 Strasbourg Cedex (France); Riehm, S. [Service de Radiologie I, Hopital de Hautepierre, 67098 Strasbourg Cedex (France)

    2010-05-15

    The facial nerve is responsible for the motor innervation of the face. It has a visceral motor function (lacrimal, submandibular, sublingual glands and secretion of the nose); it conveys a great part of the taste fibers, participates to the general sensory of the auricle (skin of the concha) and the wall of the external auditory meatus. The facial mimic, production of tears, nasal flow and salivation all depend on the facial nerve. In order to image the facial nerve it is mandatory to be knowledgeable about its normal anatomy including the course of its efferent and afferent fibers and about relevant technical considerations regarding CT and MR to be able to achieve high-resolution images of the nerve.

  3. Facial Areas and Emotional Information

    Science.gov (United States)

    Boucher, Jerry D.; Ekman, Paul

    1975-01-01

    Provides strong support for the view that there is no one area of the face which best reveals emotion, but that the value of the different facial areas in distinguishing emotions depends upon the emotion being judged. (Author)

  4. Facial Areas and Emotional Information

    Science.gov (United States)

    Boucher, Jerry D.; Ekman, Paul

    1975-01-01

    Provides strong support for the view that there is no one area of the face which best reveals emotion, but that the value of the different facial areas in distinguishing emotions depends upon the emotion being judged. (Author)

  5. Contact sensitivity in patients with recalcitrant atopic dermatitis.

    Science.gov (United States)

    Tamagawa-Mineoka, Risa; Masuda, Koji; Ueda, Sachiko; Nakamura, Naomi; Hotta, Eri; Hattori, Junko; Minamiyama, Rina; Yamazaki, Akiko; Katoh, Norito

    2015-07-01

    Patients with atopic dermatitis are usually responsive to conventional treatment such as topical steroids; however, they are sometimes refractory to the treatment. The influence of contact sensitivities on the course of patients with recalcitrant atopic dermatitis is not known. The aim of this study was to investigate whether contact sensitivities affect the course of patients with recalcitrant atopic dermatitis. We evaluated 45 patients with atopic dermatitis who had failed conventional therapy. Patch testing was performed with the Japanese standard series, metal series and/or suspected items. A total of 15 patients had a positive patch test reaction to at least one allergen. The most common allergens were nickel, topical drugs and rubber accelerators. Avoidance of products or food containing allergic substances greatly or partially improved skin symptoms in nine patients. These results suggest that contact allergens and metals may be critical factors causing eczematous lesions in patients with recalcitrant atopic dermatitis.

  6. Occupational contact dermatitis in blue-collar workers

    DEFF Research Database (Denmark)

    Schwensen, Jakob F; Menné, Torkil; Veien, Niels K

    2014-01-01

    BACKGROUND: Blue-collar workers have a high risk of occupational contact dermatitis, but epidemiological studies are scarce. OBJECTIVES: To investigate allergic contact dermatitis in blue-collar workers with dermatitis registered by the Danish Contact Dermatitis Group. METHODS: A retrospective...... analysis of patch test data from 1471 blue-collar workers and 1471 matched controls tested between 2003 and 2012 was performed. A logistic regression was used to test for associations. RESULTS: The blue-collar workers often had occupational hand dermatitis (p ... observed among blue-collar workers (19.6%) than among controls (23.9%) (p = 0.005). Allergens with a statistically significant association with the occupational group of blue-collar workers were epoxy resins, methyldibromo glutaronitrile, 2-bromo-2-nitro-1,3-propanediol, potassium dichromate...

  7. Association between cobalt allergy and dermatitis caused by leather articles

    DEFF Research Database (Denmark)

    Bregnbak, David; Thyssen, Jacob P; Zachariae, Claus

    2015-01-01

    BACKGROUND: Cobalt is a strong skin sensitizer and a prevalent contact allergen. Recent studies have recognized exposure to leather articles as a potential cause of cobalt allergy. OBJECTIVES: To examine the association between contact allergy to cobalt and a history of dermatitis resulting from ....... CONCLUSIONS: Our study suggests a positive association between cobalt allergy and a history of dermatitis caused by non-occupational exposure to leather articles.......BACKGROUND: Cobalt is a strong skin sensitizer and a prevalent contact allergen. Recent studies have recognized exposure to leather articles as a potential cause of cobalt allergy. OBJECTIVES: To examine the association between contact allergy to cobalt and a history of dermatitis resulting from...... as the most frequent exposure source causing dermatitis in the case group. Although the case group significantly more often reported non-occupational dermatitis caused by leather exposure (p

  8. A REVIEW ON FACIAL NEURALGIAS

    OpenAIRE

    Solanki, Gaurav

    2010-01-01

    Facial neuralgias are produced by a change in neurological structure or function. This type of neuropathic pain affects the mental health as well as quality of life of patients. There are different types of neuralgias affecting the oral and maxillofacial region. These unusual pains are linked to some possible mechanisms. Various diagnostic tests are done to diagnose the proper cause of facial neuralgia and according to it the medical and surgical treatment is done to provide relief to patient.

  9. Animating facial images with drawings

    OpenAIRE

    Tunali, Gamze Dilek

    1996-01-01

    Ankara : Bilkent Univ., 1996. Thesis (Master's) -- Bilkent University, 1996. Includes bibliographical references leaves 54-56. The work presented here describes the power of 2D animation with texture mai^ping controlled by line drawings. Animation is specifically intended for facial animation and not restricted by the human face. We initially have a sequence of facial images which are taken from a video sequence of the same face and an image of another face to be animated...

  10. Pediatric facial injuries: It's management

    Science.gov (United States)

    Singh, Geeta; Mohammad, Shadab; Pal, U. S.; Hariram; Malkunje, Laxman R.; Singh, Nimisha

    2011-01-01

    Background: Facial injuries in children always present a challenge in respect of their diagnosis and management. Since these children are of a growing age every care should be taken so that later the overall growth pattern of the facial skeleton in these children is not jeopardized. Purpose: To access the most feasible method for the management of facial injuries in children without hampering the facial growth. Materials and Methods: Sixty child patients with facial trauma were selected randomly for this study. On the basis of examination and investigations a suitable management approach involving rest and observation, open or closed reduction and immobilization, trans-osseous (TO) wiring, mini bone plate fixation, splinting and replantation, elevation and fixation of zygoma, etc. were carried out. Results and Conclusion: In our study fall was the predominant cause for most of the facial injuries in children. There was a 1.09% incidence of facial injuries in children up to 16 years of age amongst the total patients. The age-wise distribution of the fracture amongst groups (I, II and III) was found to be 26.67%, 51.67% and 21.67% respectively. Male to female patient ratio was 3:1. The majority of the cases of facial injuries were seen in Group II patients (6-11 years) i.e. 51.67%. The mandibular fracture was found to be the most common fracture (0.60%) followed by dentoalveolar (0.27%), mandibular + midface (0.07) and midface (0.02%) fractures. Most of the mandibular fractures were found in the parasymphysis region. Simple fracture seems to be commonest in the mandible. Most of the mandibular and midface fractures in children were amenable to conservative therapies except a few which required surgical intervention. PMID:22639504

  11. Is frictional lichenoid dermatitis a minor variant of atopic dermatitis or a photodermatosis

    Directory of Open Access Journals (Sweden)

    Kabir Sardana

    2015-01-01

    Full Text Available Context: Frictional lichenoid dermatitis. Background: Frictional lichenoid dermatitis (FLE is an entity that is probably under diagnosed and has been variably associated with either friction and/or atopy with a distinctive seasonal variation. Aims and Objectives : To study correlation of FLE with UV index and to assess its association with atopic dermatitis. Materials and Methods: A cross sectional analysis of children with FLE was done, over a period of 6 years in two tertiary hospitals. A detailed history and examination was done to assess the features of atopic dermatitis. The number of cases seen per month was compared with the mean monthly UV index. Two-tailed significance tests using Pearson′s coefficient of correlation and T-test were used to interpret the data. (P < 0.05. Results: One hundred seventy-four patients were studied using the UKC criterion 17.2% of the patients had AD while xerosis (40.3% was the predominant cutaneous finding. The number of patients seen in summer was more than in winter (P < 0.05 but there was no statistical difference between the cases in winter and spring. There was a significant correlation of the number of cases per month with UV index (P = 0.019. Almost 42% of patients gave a history of recurrence. Conclusions : FLE is probably not associated with atopic dermatitis and is likely to be related to the ambient UV index though a larger cohort with meticulous follow up may be needed to draw a final conclusion. Statistical Analysis Used: The Pearson′s coefficient of correlation was used for comparing the cases per month with the UV index. The tests of hypothesis used included the paired T-tests. F-test of variance, Welch test, Wilcoxon rank sum test and the Kolmogorov-Smirnov Test. P < 0.05 was considered significant.

  12. Rosmarinus officinalis L. as cause of contact dermatitis.

    Science.gov (United States)

    Miroddi, M; Calapai, G; Isola, S; Minciullo, P L; Gangemi, S

    2014-01-01

    Because of the widespread use of botanicals, it has become crucial for health professionals to improve their knowledge about safety problems. Several herbal medicines contain chemicals with allergenic properties responsible for contact dermatitis. Among these, one is Rosmarinus officinalis L. (rosemary), a plant used since ancient times in folk medicine; at the present time it is used worldwide as a spice and flavouring agent, as a preservative and for medicinal and cosmetic purposes. The present article aims to revise and summarise scientific literature reporting cases of contact dermatitis caused by the use of R. officinalis as a raw material or as herbal preparations. Published case reports were researched on the following databases and search engines: PUBMED, MEDLINE, EMBASE, Google Scholar, Scopus. The used keywords were: R. officinalis and rosemary each alone or combined with the words allergy, contact dermatitis, allergic contact dermatitis, sensitisation and occupational dermatitis. The published case reports show that both rosemary extracts and raw material can be responsible for allergic contact dermatitis. Two cases related to contact dermatitis caused by cross-reactivity between rosemary and thyme were also commented. The diterpene carnosol, a chemical constituent of this plant, has been imputed as a common cause for this reaction. The incidence of contact dermatitis caused by rosemary is not common, but it could be more frequent with respect to the supposed occurrence. It seems plausible that cases of contact dermatitis caused by rosemary are more frequent with respect to the supposed occurrence, because they could be misdiagnosed. For this reason, this possibility should be carefully considered in dermatitis differential diagnosis.

  13. Developmental facial paralysis: a review.

    Science.gov (United States)

    Terzis, Julia K; Anesti, Katerina

    2011-10-01

    The purpose of this study is to clarify the confusing nomenclature and pathogenesis of Developmental Facial Paralysis, and how it can be differentiated from other causes of facial paralysis present at birth. Differentiating developmental from traumatic facial paralysis noted at birth is important for determining prognosis, but also for medicolegal reasons. Given the dramatic presentation of this condition, accurate and reliable guidelines are necessary in order to facilitate early diagnosis and initiate appropriate therapy, while providing support and counselling to the family. The 30 years experience of our center in the management of developmental facial paralysis is dependent upon a thorough understanding of facial nerve embryology, anatomy, nerve physiology, and an appreciation of well-recognized mishaps during fetal development. It is hoped that a better understanding of this condition will in the future lead to early targeted screening, accurate diagnosis and prompt treatment in this population of facially disfigured patients, which will facilitate their emotional and social rehabilitation, and their reintegration among their peers.

  14. Qualitative vs. quantitative atopic dermatitis criteria

    DEFF Research Database (Denmark)

    Andersen, R M; Thyssen, J P; Maibach, H I

    2016-01-01

    on the importance of atopic features - subjective, objective, and those derived from laboratory tests - the new partly promising AD biomarkers. 'Atopy', introduced in 1923, denoted 'the sense of a strange disease without a precise place in the body'. A decade later, Sulzberger and Hill, first defined 'atopic...... to well embrace various atopic phenotypes. Pruritus, xerosis, typical morphology/distribution of dermatitis and tendency to a relapsing/chronic course are common basic features in AD criteria, whereas skin sensitivity, heredity and various ill-defined atopic stigmata also seem to comprise the atopic...

  15. Topical therapy in atopic dermatitis in children

    Directory of Open Access Journals (Sweden)

    Dharshini Sathishkumar

    2016-01-01

    Full Text Available Atopic dermatitis (AD is a common, chronic childhood skin disorder caused by complex genetic, immunological, and environmental interactions. It significantly impairs quality of life for both child and family. Treatment is complex and must be tailored to the individual taking into account personal, social, and emotional factors, as well as disease severity. This review covers the management of AD in children with topical treatments, focusing on: education and empowerment of patients and caregivers, avoidance of trigger factors, repair and maintenance of the skin barrier by correct use of emollients, control of inflammation with topical corticosteroids and calcineurin inhibitors, minimizing infection, and the use of bandages and body suits.

  16. Oscar Wilde's skin disease: allergic contact dermatitis?

    Science.gov (United States)

    Nater, J P

    1992-07-01

    During the last years of his life, Oscar Wilde (1856-1900) suffered from a suppurating otitis media as well as from an unidentified skin disease. The eruption was localized to his face, arms, chest and back and itched severely. A new theory is suggested, based on the fact that Wilde almost certainly used a dye to conceal his rapidly graying hair. He sensitized himself to p-phenylenediamine and developed a stubborn allergic contact dermatitis. Patch testing, the only proof of such a diagnosis, had not yet been devised.

  17. Atopic Dermatitis: Racial and Ethnic Differences.

    Science.gov (United States)

    Mei-Yen Yong, Adeline; Tay, Yong-Kwang

    2017-07-01

    Atopic dermatitis (AD) is a common, chronic inflammatory skin condition affecting up to 20% of children and 3% of adults worldwide. There is wide variation in the prevalence of AD among different countries. Although the frequency of AD is increasing in developing countries, it seems to have stabilized in developed countries, affecting approximately 1 in 5 schoolchildren. Adult-onset AD is not uncommon and is significantly higher, affecting between 11% and 13% of adults in some countries, for example, Singapore, Malaysia, and Sweden. AD is thus associated with significant health care economic burden in all age groups. Copyright © 2017 Elsevier Inc. All rights reserved.

  18. Seventy Five Cases Of Exfoliative Dermatitis

    Directory of Open Access Journals (Sweden)

    Bandyaopadhyay Debabrata

    1999-01-01

    Full Text Available A study of 75 cases of exfoliative dermatitis showed a male preponderance (M:F=4.77:1 with highest frequency of occurrence in the fifth and sixth decades. Cutaneous ailments were responsible for 64% of cases, among which psoriasis was the commonest disease followed by various types of eczema. The syndrome was caused by drugs in 12% of the cases and malignancy in 2.67%. In 21.33% of patients the cause remained undetermined. The systemic changes and the laboratory findings are described.

  19. [New pets, allergens and allergic dermatitis].

    Science.gov (United States)

    Brajon, D; Waton, J; Schmutz, J-L; Barbaud, A

    2014-10-01

    The number of household pets increased greatly during the twentieth century, with the numbers of new pets (NP, i.e. any pet other than cats and dogs) rising especially sharply over the last decade. Contact with such animals, whose owners do not always know how to look after them properly, expose the population to new risks such as trauma, infection and allergy. While the most common allergies are respiratory, allergic skin reactions, both immediate and delayed, may also result from contact with these new allergens. The animal itself or its environment may be the cause. Herein, we review NPs and reports of allergic dermatitis associated with them.

  20. Remote Cutaneous Breast Carcinoma Metastasis Mimicking Dermatitis

    Directory of Open Access Journals (Sweden)

    Annakan V Navaratnam

    2015-01-01

    Full Text Available Cutaneous metastases from primary internal malignancies are an uncommon presentation. Cutaneous metastases are more frequently seen in breast cancer than in any other visceral malignancy in women. Medical practitioners should be vigilant of the possibility of unusual presentations of metastatic disease in breast cancer patients with lobular carcinoma presenting as cutaneous lesions mimicking benign dermatological conditions. Herein, we present a case of a 75-year-old woman presenting with cutaneous lobular breast carcinoma metastases on her anterior right leg, which had previously been misdiagnosed as dermatitis for 9 years.

  1. Occupational allergic contact dermatitis caused by isocyanates.

    Science.gov (United States)

    Goossens, A; Detienne, T; Bruze, M

    2002-11-01

    Between 1978 and 2001, 22 patients were diagnosed with occupation-related allergic contact dermatitis from isocyanates and/or polyurethanes in our clinic. 13 had a positive reaction to the isocyanates, of whom 10 also reacted to diaminodiphenylmethane (MDA), which is used in the production or processing of isocyanates and polyurethanes; 9 reacted only to MDA. The object of the present study was to identify the trades and industries responsible for the development of contact allergy to these resins. Such patients must be patch tested with the isocyanates contacted at work, and account must be taken of positive reactions to MDA as a marker for isocyanate sensitivity.

  2. Contact Dermatitis Associated with Mandragora Plant

    Directory of Open Access Journals (Sweden)

    Yavuz Katırcı

    2014-01-01

    Full Text Available Mandragora plant contains 80 different substances including alkoloids such as mandragorine, hiyosiyamine, and skapolamine. It presents sedative, aphrodisiac, emetic, analgesic, and anesthetic effects. In our presentation, we studied the case of a 58-year-old female patient who developed allergic contact dermatitis following the application of Mandragora roots to the skin for the treatment of leg pains. Plants such as Mandragora, which contain many chemicals, must be used carefully. Further, emergency physicians must be aware of the side effects of plants used in traditional medicine and show great accuracy at the diagnosis-treatment point.

  3. The facial expression of schizophrenic patients applied with infrared thermal facial image sequence

    National Research Council Canada - National Science Library

    Bo-Lin Jian; Chieh-Li Chen; Wen-Lin Chu; Min-Wei Huang

    2017-01-01

    .... Thus, this study used non-contact infrared thermal facial images (ITFIs) to analyze facial temperature changes evoked by different emotions in moderately and markedly ill schizophrenia patients...

  4. The pH of water from various sources: an overview for recommendation for patients with atopic dermatitis.

    Science.gov (United States)

    Kulthanan, Kanokvalai; Nuchkull, Piyavadee; Varothai, Supenya

    2013-07-01

    Patients with atopic dermatitis (AD) have increased susceptibility to irritants. Some patients have questions about types of water for bathing or skin cleansing. We studied the pH of water from various sources to give an overview for physicians to recommend patients with AD. Water from various sources was collected for measurement of the pH using a pH meter and pH-indicator strips. Bottled drinking still water had pH between 6.9 and 7.5 while the sparkling type had pH between 4.9 and 5.5. Water derived from home water filters had an approximate pH of 7.5 as same as tap water. Swimming pool water had had pH between 7.2 and 7.5 while seawater had a pH of 8. Normal saline and distilled water had pH of 5.4 and 5.7, respectively. Facial mineral water had pH between 7.5 and 8, while facial makeup removing water had an acidic pH. Normal saline, distilled water, bottled sparkling water and facial makeup removing water had similar pH to that of normal skin of normal people. However, other factors including benefits of mineral substances in the water in terms of bacteriostatic and anti-inflammation should be considered in the selection of cleansing water.

  5. Effects of facial hard tissue surgery on facial aesthetics: changes in facial content and frames.

    Science.gov (United States)

    Choi, Jin-Young; Lee, Sang-Hoon; Baek, Seung-Hak

    2012-11-01

    Aesthetic units of the face can be divided into facial content (FC; eyes, nose, lips, and mouth), anterior facial frame (AFF; a contour line from the trichion, the temporal line of the frontal bone, the lateral orbital rim, the most lateral line of the anterior part of the zygomatic body, the anterior border of the masseter muscle, to the inferior border of the chin), and posterior facial frame (PFF; a contour line from the hairline, the zygomatic arch, to the ramus and gonial angle area of the mandible). The size and shape of each FC and the balance and proportion between FCs create a unique appearance for each person. The facial form can be determined through the combination of AFF and PFF. In the Asian population, clinicians frequently encounter problems of FC (eg, acute nasolabial angle, protrusive and everted lips, nonconsonant lip line, or lip canting), AFF (eg, midface hypoplasia, protrusive and asymmetric chin, vertical deficiency/excess of the anterior maxilla and symphysis, or prominent zygoma), and PFF (eg, square mandibular angle). These problems can be efficiently and effectively corrected through the combination of hard tissue surgery such as anterior segmental osteotomy, genioplasty, mandibular angle reduction, malarplasty, and orthognathic surgery. Therefore, the purposes of this article were to introduce the concepts of FC, AFF, and PFF, and to explain the effects of facial hard tissue surgery on facial aesthetics.

  6. An Unusually Severe Case of Dermatosis Neglecta: A Diagnostic Challenge

    Directory of Open Access Journals (Sweden)

    Irma Margarita Pérez-Rodríguez

    2014-08-01

    Full Text Available Dermatosis neglecta is a condition secondary to lack of cleanliness, characterized by the formation of hyperkeratotic plaques located in a particular region of the body, usually due to a disability, and it is considered a diagnostic challenge because it can mimic other entities. We present the case of an 18-year-old woman with a 2-month history of progressive brown verrucous plaque in her face. Our first impression was seborrheic dermatitis and she was treated with facial cleanser soap and topic hydrocortisone 1%. One month later, she arrived with new lesions. Because of this our diagnosis changed to Darier's disease versus seborrheic pemphigus versus foliaceus pemphigus. Histopathology and immunofluorescence studies were compatible with seborrheic dermatitis. The patient complained of depression and social withdrawal and denied facial cleansing. Facial cleansing was performed during consultation presenting resolution of the lesions, which confirmed the diagnosis of dermatosis neglecta. Dermatosis neglecta is a disease that can be frequently misdiagnosed, since it has many differential diagnoses, such as hyperkeratotic syndromes. It should be recognized early and aggressive diagnostic and therapeutic methods should be avoided.

  7. Lichenoid tissue reaction/interface dermatitis: recognition, classification, etiology, and clinicopathological overtones.

    Science.gov (United States)

    Sehgal, Virendra N; Srivastava, Govind; Sharma, Sonal; Sehgal, Shruti; Verma, Prashant

    2011-01-01

    Lichenoid tissue reaction or interface dermatitis embrace several clinical conditions, the prototype of which is lichen planus and its variants, drug induced lichenoid dermatitis, special forms of lichenoid dermatitis, lichenoid dermatitis in lupus erythematosus, and miscellaneous disorders showing lichenoid dermatitis, the salient clinical and histological features of which are described to facilitate their diagnosis. Background of lichenoid reaction pattern has been briefly outlined to enlighten those interested in this entity.

  8. Lichenoid tissue reaction/interface dermatitis: Recognition, classification, etiology, and clinicopathological overtones

    OpenAIRE

    Sehgal, Virendra N; Govind Srivastava; Sonal Sharma; Shruti Sehgal; Prashant Verma

    2011-01-01

    Lichenoid tissue reaction or interface dermatitis embrace several clinical conditions, the prototype of which is lichen planus and its variants, drug induced lichenoid dermatitis, special forms of lichenoid dermatitis, lichenoid dermatitis in lupus erythematosus, and miscellaneous disorders showing lichenoid dermatitis, the salient clinical and histological features of which are described to facilitate their diagnosis. Background of lichenoid reaction pattern has been briefly outlined to enli...

  9. Lichenoid tissue reaction/interface dermatitis: Recognition, classification, etiology, and clinicopathological overtones

    Directory of Open Access Journals (Sweden)

    Virendra N Sehgal

    2011-01-01

    Full Text Available Lichenoid tissue reaction or interface dermatitis embrace several clinical conditions, the prototype of which is lichen planus and its variants, drug induced lichenoid dermatitis, special forms of lichenoid dermatitis, lichenoid dermatitis in lupus erythematosus, and miscellaneous disorders showing lichenoid dermatitis, the salient clinical and histological features of which are described to facilitate their diagnosis. Background of lichenoid reaction pattern has been briefly outlined to enlighten those interested in this entity.

  10. A Contemporary Approach to Facial Reanimation.

    Science.gov (United States)

    Jowett, Nate; Hadlock, Tessa A

    2015-01-01

    The management of acute facial nerve insult may entail medical therapy, surgical exploration, decompression, or repair depending on the etiology. When recovery is not complete, facial mimetic function lies on a spectrum ranging from flaccid paralysis to hyperkinesis resulting in facial immobility. Through systematic assessment of the face at rest and with movement, one may tailor the management to the particular pattern of dysfunction. Interventions for long-standing facial palsy include physical therapy, injectables, and surgical reanimation procedures. The goal of the management is to restore facial balance and movement. This article summarizes a contemporary approach to the management of facial nerve insults.

  11. Computer Aided Facial Prosthetics Manufacturing System

    Directory of Open Access Journals (Sweden)

    Peng H.K.

    2016-01-01

    Full Text Available Facial deformities can impose burden to the patient. There are many solutions for facial deformities such as plastic surgery and facial prosthetics. However, current fabrication method of facial prosthetics is high-cost and time consuming. This study aimed to identify a new method to construct a customized facial prosthetic. A 3D scanner, computer software and 3D printer were used in this study. Results showed that the new developed method can be used to produce a customized facial prosthetics. The advantages of the developed method over the conventional process are low cost, reduce waste of material and pollution in order to meet the green concept.

  12. Topical steroid addiction in atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Fukaya M

    2014-10-01

    Full Text Available Mototsugu Fukaya,1 Kenji Sato,2 Mitsuko Sato,3 Hajime Kimata,4 Shigeki Fujisawa,5 Haruhiko Dozono,6 Jun Yoshizawa,7 Satoko Minaguchi8 1Tsurumai Kouen Clinic, Nagoya, 2Department of Dermatology, Hannan Chuo Hospital, Osaka, 3Sato Pediatric Clinic, Osaka, 4Kimata Hajime Clinic, Osaka, 5Fujisawa Dermatology Clinic, Tokyo, 6Dozono Medical House, Kagoshima, 7Yoshizawa Dermatology Clinic, Yokohama, 8Department of Dermatology, Kounosu Kyousei Hospital, Saitama, Japan Abstract: The American Academy of Dermatology published a new guideline regarding topical therapy in atopic dermatitis in May 2014. Although topical steroid addiction or red burning skin syndrome had been mentioned as possible side effects of topical steroids in a 2006 review article in the Journal of the American Academy of Dermatology, no statement was made regarding this illness in the new guidelines. This suggests that there are still controversies regarding this illness. Here, we describe the clinical features of topical steroid addiction or red burning skin syndrome, based on the treatment of many cases of the illness. Because there have been few articles in the medical literature regarding this illness, the description in this article will be of some benefit to better understand the illness and to spur discussion regarding topical steroid addiction or red burning skin syndrome. Keywords: topical steroid addiction, atopic dermatitis, red burning skin syndrome, rebound, corticosteroid, eczema

  13. Genetic variation of contact dermatitis in broilers.

    Science.gov (United States)

    Ask, B

    2010-05-01

    This study aimed to investigate the presence of genetic variation in footpad dermatitis (FPD) and hock burns (HB) and the possibility to genetically select against these. A field trial including 10 commercial broiler lines (n = 102 to 265) was carried out at 2 Dutch farms. Footpad dermatitis and HB were subjectively scored at approximately 4, 5, and 7 wk on a scale from 0 through 5. Genetic parameters were estimated in 2 lines based on a larger data set. The overall agreement of repeated FPD and HB scores was high (0.66 to 0.86) and the scoring system was, therefore, considered reliable. Kendall's tau between left and right scores was lower than 1 (FPD: 0.73 and HB: 0.57), and both left and right FPD and HB must, therefore, be evaluated. High prevalences of FPD, but also HB, were achieved in the field trial, but lower prevalences may be sufficient for genetic evaluations and would be less detrimental to welfare. Genetic variation between and within lines was present for both FPD and HB as indicated by between-line differences and heritabilities, and selection against FPD and HB is, therefore, possible. It is important that selection is done against both FPD and HB, and such selection should not have a negative influence on the genetic improvement in BW. In contrast, continued selection for increased BW while ignoring FPD in the breeding goal is likely to lead to an increased propensity to develop FPD in broilers.

  14. Hand dermatitis in beauticians in India

    Directory of Open Access Journals (Sweden)

    Khanna Neena

    1997-01-01

    Full Text Available One hundred and sixty-one beauticians and hairdressers (146 women and 15 men were examined for the presence of hand dermatitis and those with hand eczema were patch tested with a battery of antigens standardised for beauticians. Forty-two (26.1% subjects were found to have hand dermatitis and of these, in 31 (69.3% the patch tests were positive; the following antigens elicited a positive response; paraphenylene diamine (35.5%, rubber antigens (22.6%, nickel (22.6%, shampoos (12.9%, ammonium thioglycollate (9.7%, ammonium persulphate (3.2%, henna mixture (3.2% and detergents (6.5%. In addition, irritant reaction was seen in 7; in 5 patients it was to shampoos and in 2 to ammonium persulphate. Of the 8 patients who, on questioning, had a history of atopy, 7 (87.5% had hand eczema, while 1 (12.5% did not, and this difference was statistically significant (p < 0.001, suggesting that beauticians with a history of atopy were more likely to develop hand eczema.

  15. The diagnosis and treatment of dermatitis herpetiformis

    Directory of Open Access Journals (Sweden)

    Antiga E

    2015-05-01

    Full Text Available Emiliano Antiga, Marzia Caproni Department of Surgery and Translational Medicine, Section of Dermatology, University of Florence, Florence, Italy Abstract: Dermatitis herpetiformis (DH is an inflammatory cutaneous disease with a chronic relapsing course, pruritic polymorphic lesions, and typical histopathological and immunopathological findings. According to several evidences, DH is considered the specific cutaneous manifestation of celiac disease, and the most recent guidelines of celiac disease have stated that, in celiac patients with a proven DH, a duodenal biopsy is unnecessary for the diagnosis. In this review, the most recent data about the diagnosis and the management of DH have been reported and discussed. In particular, in patients with clinical and/or histopathological findings suggestive for DH, the finding of granular IgA deposits along the dermal–epidermal junction or at the papillary tips by direct immunofluorescence (DIF assay, together with positive results for anti-tissue transglutaminase antibody testing, allows the diagnosis. Thereafter, a gluten-free diet should be started in association with drugs, such as dapsone, that are able to control the skin manifestations during the first phases of the diet. In conclusion, although DH is a rare autoimmune disease with specific immunopathological alterations at the skin level, its importance goes beyond the skin itself and may have a big impact on the general health status and the quality of life of the patients. Keywords: dermatitis herpetiformis, celiac disease, diagnosis, treatment, autoimmune disease, inflammatory cutaneous disease 

  16. Treating pediatric atopic dermatitis: current perspectives

    Directory of Open Access Journals (Sweden)

    Dimitriades VR

    2015-06-01

    Full Text Available Victoria R Dimitriades, Elizabeth Wisner Division of Allergy/Immunology, Department of Pediatrics, Louisiana State University Health Sciences Center, Children's Hospital of New Orleans, New Orleans, LA, USAAbstract: Atopic dermatitis (AD is a chronic, inflammatory skin condition which affects millions of people worldwide. It is most commonly seen in children but may also progress into adulthood. Management of this complex disease requires a multi-pronged approach which can address the myriad of issues which underscore its development. Avoidance of triggering factors is imperative in establishing consistent control of skin irritation while daily moisturization can be very effective in skin barrier repair and maintenance. Judicious use of anti-inflammatory medications has been shown to make a significant impact on both treatment as well as prevention of disease. Unfortunately, pruritus, a key feature of AD, has proven much harder to control. Finally, awareness of the risks of colonization and infection in patients with AD should be incorporated into their surveillance and management plans. While our understanding has progressed greatly regarding this disease, further research is still needed regarding future directions for both treatment and prevention. Keywords: atopic dermatitis, eczema, treatment, corticosteroids, antipruritic

  17. Probiotics and Atopic Dermatitis in Children

    Directory of Open Access Journals (Sweden)

    Gian Vincenzo Zuccotti

    2012-07-01

    Full Text Available There is increasing interest in the potential beneficial role of probiotic supplementation in the prevention and treatment of atopic diseases in children. Probiotics are defined as ingested live microorganisms that, when administered in an adequate amount, confer a health benefit to the host. They are mainly represented by Lactobacilli and Bifidobacteria. Several epidemiological data demonstrate that intestinal microflora of atopic children is different from the one of healthy children. Many literature data show that probiotics may modulate the intestinal microflora composition and may have immunomodulatory effect. Based on this hypothesis, probiotics are supposed to confer benefits to allergic diseases. Administration of probiotics when a natural population of indigenous intestinal bacteria is still developing could theoretically influence immune development by favoring the balance between Th1 and Th2 inflammatory responses. For this reason, some studies have evaluated the potential impact of probiotics supplementation in the prevention of atopic dermatitis, with contrasting results. Clinical improvement in immunoglobulin (IgE-sensitized (atopic eczema following probiotic supplementation has been reported in some published studies and the therapeutic effects of probiotics on atopic dermatitis seemed to be encouraging. However, as far as the usefulness of probiotics as a prevention strategy is concerned, results are still inconclusive. In fact, the clinical benefits of probiotic therapy depend upon numerous factors, such as the type of bacteria, dosing regimen, delivery method and other underlying host factors, such as age and diet. More studies are still needed to definitively prove the role of probiotics in the treatment of allergic eczema.

  18. New and emerging trends in the treatment of atopic dermatitis

    Directory of Open Access Journals (Sweden)

    Christina M Gelbard

    2009-01-01

    Full Text Available Christina M Gelbard1, Adelaide A Hebert1,21Departments of Dermatology; 2Pediatrics, University of Texas-Houston, Houston, TX, USAAbstract: Atopic dermatitis is a chronic, inflammatory skin condition that affects 10% to 20% of children and 1% to 3% of adults in the US. Symptoms often result in sleeplessness, psychological stress, poor self-esteem, anxiety, and poor school or work performance. The cost of atopic dermatitis is estimated to be US$0.9 to 3.8 billion every year. Topical steroids are first-line treatment for atopic dermatitis, and recent advances in vehicle technologies have resulted in improved patient tolerability and compliance. Topical calcineurin inhibitors are also safe and effective topical treatments for atopic dermatitis, and provide an additional therapeutic option for patients with this disease. Systemic immunomodulators are used in the treatment of severe refractory disease. Cyclosporine, methotrexate, azathioprine, mycophenolate mofetil, and interferon gamma have been used in the management of severe atopic dermatitis. This review highlights the current and emerging trends in the treatment of atopic dermatitis.Keywords: atopic dermatitis, topical corticosteroids, calcineurin inhibitors, methotrexate, cyclosporine, mycophenolate mofetil, IFN-γ

  19. Photopatch and UV-irradiated patch testing in photosensitive dermatitis

    Directory of Open Access Journals (Sweden)

    Reena Rai

    2016-01-01

    Full Text Available Background: The photopatch test is used to detect photoallergic reactions to various antigens such as sunscreens and drugs. Photosensitive dermatitis can be caused due to antigens like parthenium, fragrances, rubbers and metals. The photopatch test does not contain these antigens. Therefore, the Indian Standard Series (ISS along with the Standard photopatch series from Chemotechnique Diagnostics, Sweden was used to detect light induced antigens. Aim: To detect light induced antigens in patients with photosensitive dermatitis. Methods: This study was done in a descriptive, observer blinded manner. Photopatch test and ISS were applied in duplicate on the patient's back by the standard method. After 24 hours, readings were recorded according to ICDRG criteria. One side was closed and other side irradiated with 14 J/cm2 of UVA and a second set of readings were recorded after 48 hrs. Result: The highest positivity was obtained with parthenium, with 18 out of 35 (51% patients showing a positive patch test reaction with both photoallergic contact dermatitis and photoaggravation. Four patients (11% showed positive patch test reaction suggestive of contact dermatitis to potassium dichromate and fragrance mix. Six patients had contact dermatitis to numerous antigens such as nickel, cobalt, chinoform and para-phenylenediamine. None of these patients showed photoaggravation on patch testing. Conclusion: Parthenium was found to cause photoallergy, contact dermatitis with photoaggravation and contact allergy. Hence, photopatch test and UV irradiated patch test can be an important tool to detect light induced antigens in patients with photosensitive dermatitis.

  20. Diagnostic criteria for atopic dermatitis in adult Thai population

    Directory of Open Access Journals (Sweden)

    Wanitphakdeedecha Rungsima

    2007-01-01

    Full Text Available Context: Atopic dermatitis is a common disease that is diagnosed by use of Hanifin, Lobitz and Rajka′s criteria based on patient history and clinical features. However these criteria are not suitable for population-based studies. Aims: The purpose of this study is to develop a minimum list of diagnostic criteria for atopic dermatitis that is sensitive, specific, reproducible, noninvasive, applicable to adult Thai population and easy to perform in population-based studies. Settings and Design: This study was conducted at Department of Dermatology, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand. Materials and Methods: The new cases of typical mild to moderate atopic dermatitis and exactly age-matched and sex-matched controls presenting with an inflammatory skin disease other than atopic dermatitis were selected from Department of Dermatology, Faculty of Medicine Siriraj Hospital. Each subject was examined with reference to 31 clinically diagnostic features of atopic dermatitis proposed by Hanifin and Rajka. One hundred and forty patients (70 cases and 70 controls were studied. Statistical Analysis Used: Sensitivity and specificity of each criterion was calculated using the dermatologist′s diagnosis as the standard. Regression techniques were then used to derive a minimum set of diagnostic criteria. Results: Using multiple logistic regression techniques, a minimum set of diagnostic criteria for atopic dermatitis was derived: visible flexural dermatitis, history of flexural dermatitis, duration of rash> 6 months and visible dry skin. Conclusions: A minimum list of diagnostic criteria for atopic dermatitis was derived that should be of use in Thai population-based studies.

  1. Clinical observation on tretinoin cream to treat seborrheic dermatitis and acne patients%维A酸霜治疗脂溢性皮炎和痤疮的临床观察

    Institute of Scientific and Technical Information of China (English)

    武晓华

    2007-01-01

    @@ 脂溢性皮炎、痤疮好发于头面部、胸背等皮脂溢出部位,主要与病人皮脂分泌过多有关[1].我科采用维A酸霜治疗脂溢性皮炎及痤疮取得了满意效果.现报道如下.

  2. Female Facial Appearance and Health

    Directory of Open Access Journals (Sweden)

    Alan W. Gray

    2012-01-01

    Full Text Available The current study addressed whether rated femininity, attractiveness, and health in female faces are associated with numerous indices of self-reported health history (number of colds/stomach bugs/frequency of antibiotic use in a sample of 105 females. It was predicted that all three rating variables would correlate negatively with bouts of illness (with the exception of rates of stomach infections, on the assumption that aspects of facial appearance signal mate quality. The results showed partial support for this prediction, in that there was a general trend for both facial femininity and attractiveness to correlate negatively with the reported number of colds in the preceding twelve months and with the frequency of antibiotic use in the last three years and the last twelve months. Rated facial femininity (as documented in September was also associated with days of flu experienced in the period spanning the November-December months. However, rated health did not correlate with any of the health indices (albeit one marginal result with antibiotic use in the last twelve months. The results lend support to previous findings linking facial femininity to health and suggest that facial femininity may be linked to some aspects of disease resistance but not others.

  3. Cortical control of facial expression.

    Science.gov (United States)

    Müri, René M

    2016-06-01

    The present Review deals with the motor control of facial expressions in humans. Facial expressions are a central part of human communication. Emotional face expressions have a crucial role in human nonverbal behavior, allowing a rapid transfer of information between individuals. Facial expressions can be either voluntarily or emotionally controlled. Recent studies in nonhuman primates and humans have revealed that the motor control of facial expressions has a distributed neural representation. At least five cortical regions on the medial and lateral aspects of each hemisphere are involved: the primary motor cortex, the ventral lateral premotor cortex, the supplementary motor area on the medial wall, and the rostral and caudal cingulate cortex. The results of studies in humans and nonhuman primates suggest that the innervation of the face is bilaterally controlled for the upper part and mainly contralaterally controlled for the lower part. Furthermore, the primary motor cortex, the ventral lateral premotor cortex, and the supplementary motor area are essential for the voluntary control of facial expressions. In contrast, the cingulate cortical areas are important for emotional expression, because they receive input from different structures of the limbic system.

  4. Peripheral facial weakness (Bell's palsy).

    Science.gov (United States)

    Basić-Kes, Vanja; Dobrota, Vesna Dermanović; Cesarik, Marijan; Matovina, Lucija Zadro; Madzar, Zrinko; Zavoreo, Iris; Demarin, Vida

    2013-06-01

    Peripheral facial weakness is a facial nerve damage that results in muscle weakness on one side of the face. It may be idiopathic (Bell's palsy) or may have a detectable cause. Almost 80% of peripheral facial weakness cases are primary and the rest of them are secondary. The most frequent causes of secondary peripheral facial weakness are systemic viral infections, trauma, surgery, diabetes, local infections, tumor, immune disorders, drugs, degenerative diseases of the central nervous system, etc. The diagnosis relies upon the presence of typical signs and symptoms, blood chemistry tests, cerebrospinal fluid investigations, nerve conduction studies and neuroimaging methods (cerebral MRI, x-ray of the skull and mastoid). Treatment of secondary peripheral facial weakness is based on therapy for the underlying disorder, unlike the treatment of Bell's palsy that is controversial due to the lack of large, randomized, controlled, prospective studies. There are some indications that steroids or antiviral agents are beneficial but there are also studies that show no beneficial effect. Additional treatments include eye protection, physiotherapy, acupuncture, botulinum toxin, or surgery. Bell's palsy has a benign prognosis with complete recovery in about 80% of patients, 15% experience some mode of permanent nerve damage and severe consequences remain in 5% of patients.

  5. Compound facial expressions of emotion.

    Science.gov (United States)

    Du, Shichuan; Tao, Yong; Martinez, Aleix M

    2014-04-15

    Understanding the different categories of facial expressions of emotion regularly used by us is essential to gain insights into human cognition and affect as well as for the design of computational models and perceptual interfaces. Past research on facial expressions of emotion has focused on the study of six basic categories--happiness, surprise, anger, sadness, fear, and disgust. However, many more facial expressions of emotion exist and are used regularly by humans. This paper describes an important group of expressions, which we call compound emotion categories. Compound emotions are those that can be constructed by combining basic component categories to create new ones. For instance, happily surprised and angrily surprised are two distinct compound emotion categories. The present work defines 21 distinct emotion categories. Sample images of their facial expressions were collected from 230 human subjects. A Facial Action Coding System analysis shows the production of these 21 categories is different but consistent with the subordinate categories they represent (e.g., a happily surprised expression combines muscle movements observed in happiness and surprised). We show that these differences are sufficient to distinguish between the 21 defined categories. We then use a computational model of face perception to demonstrate that most of these categories are also visually discriminable from one another.

  6. [The history of facial paralysis].

    Science.gov (United States)

    Glicenstein, J

    2015-10-01

    Facial paralysis has been a recognized condition since Antiquity, and was mentionned by Hippocratus. In the 17th century, in 1687, the Dutch physician Stalpart Van der Wiel rendered a detailed observation. It was, however, Charles Bell who, in 1821, provided the description that specified the role of the facial nerve. Facial nerve surgery began at the end of the 19th century. Three different techniques were used successively: nerve anastomosis, (XI-VII Balance 1895, XII-VII, Korte 1903), myoplasties (Lexer 1908), and suspensions (Stein 1913). Bunnell successfully accomplished the first direct facial nerve repair in the temporal bone, in 1927, and in 1932 Balance and Duel experimented with nerve grafts. Thanks to progress in microsurgical techniques, the first faciofacial anastomosis was realized in 1970 (Smith, Scaramella), and an account of the first microneurovascular muscle transfer published in 1976 by Harii. Treatment of the eyelid paralysis was at the origin of numerous operations beginning in the 1960s; including palpebral spring (Morel Fatio 1962) silicone sling (Arion 1972), upperlid loading with gold plate (Illig 1968), magnets (Muhlbauer 1973) and transfacial nerve grafts (Anderl 1973). By the end of the 20th century, surgeons had at their disposal a wide range of valid techniques for facial nerve surgery, including modernized versions of older techniques.

  7. Occupational Airborne Contact Dermatitis From Proton Pump Inhibitors.

    Science.gov (United States)

    DeKoven, Joel G; Yu, Ashley M

    2015-01-01

    Few published reports have described occupational contact dermatitis from proton pump inhibitor (PPI) exposure in the literature. We present an additional case of a 58-year-old male pharmaceutical worker with an occupational airborne allergic contact dermatitis to PPIs confirmed by patch testing. This is a novel report of workplace exposure to dexlansoprazole and esomeprazole PPIs with resultant clinical contact allergy and relevant positive patch test results to these 2 agents. A literature review of all previously reported cases of occupational contact dermatitis to PPI is summarized. The case also emphasizes the importance of even minute exposures when considering workplace accommodation.

  8. Foot-pad dermatitis in broilers and turkeys

    OpenAIRE

    Berg, Charlotte C.

    1998-01-01

    Foot-pad dermatitis is a condition characterised by lesions on the ventral foot-pads of poultry. It is a type of contact dermatitis, which in an early stage results in hyperkeratosis, erosions and discoloration of the skin. The erosions can develop into ulcers. In severe cases, the foot-pad lesions may cause pain which together with a deteriorated state of health constitutes a welfare issue. It has also been indicated that broilers with severe foot-pad dermatitis show slower weight gain. The ...

  9. Development of atopic dermatitis in the DARC birth cohort

    DEFF Research Database (Denmark)

    Eller, Esben; Kjaer, Henrik Fomsgaard; Høst, Arne

    2009-01-01

    Eller E, Kjaer HF, Høst A, Andersen KE, Bindslev-Jensen C. Development of Atopic Dermatitis in the DARC birth cohort. Pediatr Allergy Immunol 2009. (c) 2009 John Wiley & Sons A/SThe aim was to describe the relapsing pattern, sensitization and prognosis of atopic dermatitis (AD) in the first 6 yr...... was measured by objective SCORing Atopic Dermatitis (SCORAD). Point-prevalence of AD peaked at 18 months of age (10%) and decreased at 36 and 72 months to slightly below 7%. The 6-yr cumulative incidence was 22.8% and sensitization was found in 43% of children with AD. It was predominately sensitization...

  10. PATHOGENETIC THERAPY FOR ATOPIC DERMATITIS IN CHILDREN: CURRENT ISSUES

    Directory of Open Access Journals (Sweden)

    G.I. Smirnova

    2006-01-01

    Full Text Available The lecture presents current opinions on the problem of topical treatment of atopic dermatitis in children discussing different topical antiainflamatory drugs with and without corticosteroids. pimecrolimus 1% cream (elidel, novartis pharma, Germany is specially emphasized among the latter. Pimecrolimus is shown to provide symptom relief and control in mild and moderate cases of atopic dermatitis, so it could become essential in preventing exacerbations and elongation of remission periods of the disease.Key words: atopic dermatitis, topical treatment, pimecrolimus 1% cream.

  11. Allergic contact dermatitis: pathophysiology applied to future therapy.

    Science.gov (United States)

    Li, Lily Y; Cruz, Ponciano D

    2004-01-01

    Contact dermatitis is a common reason for patient visits to primary-care clinics and represents up to 7% of all dermatologic consultations in the US. Substantial progress has been made in elucidating the pathophysiology of contact dermatitis, particularly the allergic form. A better understanding of pathologic mechanisms has led to improved management of cases and will continue to advance treatment modalities. The present paper reviews the pathogenesis and current treatment of allergic contact dermatitis and speculates on the prospects for improved future therapy.

  12. [Allergic contact dermatitis to diethylthiourea in a neoprene wader].

    Science.gov (United States)

    Martínez-González, M C; Goday-Buján, J J; Almagro, M; Fonseca, E

    2009-05-01

    Diethylthiourea, like other thioureas, is often used by the rubber industry and in the manufacture of neoprene. We present a patient who suffered allergic contact dermatitis to diethylthiourea in a neoprene wader and who required admission to hospital and systemic treatment. We review the literature on allergy to diethylthiourea. Thioureas are not included in the standard GEIDAC (Spanish Contact Dermatitis Research Group) battery of patch tests. In these cases, it is necessary to use a special battery of rubber allergens, which includes thiourea compounds, for diagnosis of the disease and to ensure that cases of contact allergic dermatitis to thioureas do not go undiagnosed.

  13. Investigations on the immunopathogenesis of atopic dermatitis in cats

    OpenAIRE

    Roosje, Pieternella Janna

    2003-01-01

    The term atopic dermatitis (AD) is commonly used in cats. At present, however, there is little known about the pathogenesis of feline AD. The aim was to investigate various aspects of the immunopathogenesis in a defined group of cats with signs and symptoms of atopic dermatitis and compare our findings with the immunoregulation of atopic dermatitis in humans. The presence of antigen-specific IgE in serum of AD cats was investigated by means of the Prausnitz-Küstner (PK) test and the passive c...

  14. Excipients in Oral Antihistamines Can Perpetuate Allergic Contact Dermatitis.

    Science.gov (United States)

    Tocci, Elizabeth M; Robinson, Amanda; Belazarian, Leah; Foley, Elizabeth; Wiss, Karen; Silvestri, Dianne L

    2015-01-01

    Propylene glycol is a well-documented causative agent of allergic contact dermatitis (ACD). It is also reported to cause systemic dermatitis after ingestion of foods or medicines containing it and after intravenous injection of a medicine with propylene glycol in its base. We describe two adolescents with sensitivity to propylene glycol confirmed by patch testing whose dermatitis improved dramatically after cessation of oral antihistamines containing propylene glycol. We report these cases to alert providers to the potential for worsening of ACD due to systemic exposure to propylene glycol in patients with a cutaneous sensitivity to the allergen.

  15. Autosensitisation (Autoeczematisation reactions in a case of diaper dermatitis candidiasis

    Directory of Open Access Journals (Sweden)

    Anca Chirac

    2014-01-01

    Full Text Available Diaper dermatitis is the most common cutaneous diagnosis in infants. Most cases are associated with the yeast colonisation of Candida or diaper dermatitis candidiasis (DDC. It is an irritating and inflammatory acute dermatitis in the perineal and perianal areas resulting from the occlusion and irritation caused by diapers. Autoeczematization to a distant focus of dermatophyte infection very rarely presents as DDC. We present a 1-month-old boy with lesion on diaper area (gluteal area, perineum, groin and genitalia and with clusters of pustules and vesicles on a large erythematous base over the dorsal area of both hands.

  16. RESULTS OF APPLYING POLYVITAMIN COMPLEX FOR CHILDREN WITH ATOPIC DERMATITIS

    Directory of Open Access Journals (Sweden)

    N.A. Ivanova

    2007-01-01

    Full Text Available The article presents findings of applying vitamin-and-mineral complex (VMC for children frequently suffering from diseases and children with atopic dermatitis. It shows that usage of VMC within a complex therapy promotes regression of subnormal vitamin provision symptoms, as well as symptoms of the core disease. This happens against heightened vitamin content in child's organism — which was proven with the test of A and E vitamins content in blood. The research has demonstrated a quite good tolerance of VMC by children suffering from atopic dermatitis.Key words: children frequently suffering from diseases, atopic dermatitis, vitamins, treatment.

  17. Slowing down facial movements and vocal sounds enhances facial expression recognition and facial-vocal imitation in children with autism

    OpenAIRE

    Tardif, Carole; Lainé, France; Rodriguez, Mélissa; Gepner, Bruno

    2007-01-01

    International audience; This study examined the effects of slowing down presentation of facial expressions and their corresponding vocal sounds on facial expression recognition and facial and/or vocal imitation in children with autism. Twelve autistic children and twenty-four normal control children were presented with emotional and non-emotional facial expressions on CD-Rom, under audio or silent conditions, and under dynamic visual conditions (slowly, very slowly, at normal speed) plus a st...

  18. Vitamin D in atopic dermatitis, chronic urticaria and allergic contact dermatitis.

    Science.gov (United States)

    Quirk, Shannon K; Rainwater, Ellecia; Shure, Anna K; Agrawal, Devendra K

    2016-08-01

    Vitamin D influences allergen-induced pathways in the innate and adaptive immune system, and its potential immunomodulatory role in allergic skin disorders has been explored. This comprehensive review article provides an overview of the role of vitamin D in three common dermatologic conditions: atopic dermatitis (AD), chronic urticaria, and allergic contact dermatitis (ACD). Whereas the literature regarding vitamin D and AD has resulted in mixed findings, several studies have described an inverse relationship between vitamin D levels and AD severity, and improvement in AD with vitamin D supplementation. Similarly, several studies report an inverse relationship between vitamin D levels and severity of chronic urticaria. Although current research in humans remains limited, an increased likelihood of ACD has been demonstrated in vitamin D-deficient mice. Additional well-designed clinical trials will be necessary to determine whether vitamin D supplementation should be recommended for prevention or adjuvant treatment of these common dermatologic conditions.

  19. Live bee acupuncture (Bong-Chim) dermatitis: dermatitis due to live bee acupuncture therapy in Korea.

    Science.gov (United States)

    Park, Joon Soo; Lee, Min Jung; Chung, Ki Hun; Ko, Dong Kyun; Chung, Hyun

    2013-12-01

    Live bee acupuncture (Bong-Chim) dermatitis is an iatrogenic disease induced by so-called live bee acupuncture therapy, which applies the honeybee (Apis cerana) stinger directly into the lesion to treat various diseases in Korea. We present two cases of live bee acupuncture dermatitis and review previously published articles about this disease. We classify this entity into three stages: acute, subacute, and chronic. The acute stage is an inflammatory reaction, such as anaphylaxis or urticaria. In the chronic stage, a foreign body granuloma may develop from the remaining stingers, similar to that of a bee sting reaction. However, in the subacute stage, unlike bee stings, we see the characteristic histological "flame" figures resulting from eosinophilic stimulation induced by excessive bee venom exposure. We consider this stage to be different from the adverse skin reaction of accidental bee sting.

  20. Overview of facial paralysis: current concepts.

    Science.gov (United States)

    Melvin, Thuy-Anh N; Limb, Charles J

    2008-05-01

    Facial paralysis represents the end result of a wide array of disorders and heterogeneous etiologies, including congenital, traumatic, infectious, neoplastic, and metabolic causes. Thus, facial palsy has a diverse range of presentations, from transient unilateral paresis to devastating permanent bilateral paralysis. Although not life-threatening, facial paralysis remains relatively common and can have truly severe effects on one's quality of life, with important ramifications in terms of psychological impact and physiologic burden. Prognosis and outcomes for patients with facial paralysis are highly dependent on the etiologic nature of the weakness as well as the treatment offered to the patient. Facial plastic surgeons are often asked to manage the sequelae of long-standing facial paralysis. It is important, however, for any practitioner who assists this population to have a sophisticated understanding of the common etiologies and initial management of facial paralysis. This article reviews the more common causes of facial paralysis and discusses relevant early treatment strategies.