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Sample records for fabio claudio ferracchiati

  1. Claudio Katz Claudio Katz

    Directory of Open Access Journals (Sweden)

    2010-10-01

    Full Text Available Claudio Katz nació en Argentina, en 1954. Es economista, integrante del Consejo Nacional de Ciencia y Tecnología de la República Argentina, profesor en la Universidad de Buenos Aires y director de varios proyectos de investigación. Es autor de numerosos textos de interpretación del capitalismo contemporáneo y de la crisis económica global. Participa activamente en los foros continentales de impugnación del libre-comercio, el endeudamiento externo y la militarización. Como integrante del EDI (Economistas de Izquierda ha publicado varios estudios sobre la coyuntura política y social de la Argentina y de América Latina. Entre sus publicaciones, se destacan sus libros El porvenir del socialismo (2004 y Las disyuntivas de la izquierda en América Latina (primera edición, 2008, que recibieron menciones honoríficas del Premio Libertador al Pensamiento Crítico, además de 'El rediseño de América Latina. Alca, Mercosur y Alba' (2006 y 'La economía marxista, hoy. Seis debates teóricos' (2009. En esta entrevista, concedida a la revista Trabalho, Educação e Saúde en junio de 2010, Katz expone algunas reflexiones sobre la realidad latinoamericana contemporánea, destacando la crítica al llamado 'nuevo desarrollismo', la perspectiva socialista del concepto de democracia y la vigencia del marxismo latinoamericano.Claudio Katz was born in Argentina in 1954. He is an economist, a member of the National Council for Science and Technology of Argentina, a professor at the University of Buenos Aires, and the director of several research projects. Katz is the author of numerous interpretation texts of contemporary capitalism and about the global economic crisis. He participates actively in continental forums on free trade disputes, external debt, and militarization. As a member of the of EDI (Leftist Economists, he has published several studies on the political and social situation of both Argentina and of Latin America. Among his publications

  2. FabIO

    DEFF Research Database (Denmark)

    Bergbäck Knudsen, Erik; Sørensen, Henning O.; Wright, Jonathan P.

    2013-01-01

    FabIO is a Python module written for easy and transparent reading of raw two-dimensional data from various X-ray detectors. The module provides a function for reading any image and returning a fabioimage object which contains both metadata (header information) and the raw data. All fabioimage...

  3. Fabio Viola, Gamification, Arduino Viola Editore, 2011

    Directory of Open Access Journals (Sweden)

    Federico Giordano

    2012-05-01

    Full Text Available Il testo di Fabio Viola ha un’impostazione decisamente divulgativa, con intenti definitori e riassuntivi, uno stile molto più prossimo al giornalistico che all’accademico e frequenti incursioni nella dimensione quantitativa.

  4. A-Ha. Drum'n'bassi supernimi FABIO

    Index Scriptorium Estoniae

    2002-01-01

    7.sept. annab norra menukaim popansambel A-Ha Tallinnas Lauluväljakul kontserdi, kus presenteerib ka oma viimast albumit "Lifelines". 14. sept.tuleb drum'n'bassi spetsialist Fabio Tallinna üritusele Circulation

  5. Claudio Baglietto, Kant e l’antifascismo

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2011-07-01

    Full Text Available Depositato nell’Archivio Marini, il documento contiene un saggio incompiuto di Claudio Baglietto, filosofo normalista morto prematuramente nel 1940, che scelse l’esilio a Basilea a causa della sua obiezione di coscienza contro il servizio militare e contro il fascismo. Il saggio è preceduto da una presentazione di Aldo Capitini, suo compagno di studi e d’idee, e [...

  6. Fabio Cleto, Intrigo internazionale. Pop, chic, spie degli anni sessanta.

    Directory of Open Access Journals (Sweden)

    Mariangela Bio

    2013-05-01

    Full Text Available Il testo di Fabio Cleto scorre come un lungo piano sequenza su un caso culturale a lungo dibattuto e sviscerato, il camp. Fenomeno ineffabile e sfuggente, da sempre, a facili classificazioni. Ma, sebbene la letteratura sul camp sia alquanto vasta e i tentativi di definizione talvolta impervi, è possibile riconoscere nel libro di Cleto indubbi elementi di originalità e pregio.

  7. El monumento de Playa Giron. Fabio Penteado y la arquitectura como ejercicio de la libertad

    National Research Council Canada - National Science Library

    Giroto, Ivo Renato

    2012-01-01

    Este articulo pretende establecer los vinculos historico-culturales que influyen en la arquitectura moderna brasilena y, consecuentemente, en la prolifera obra del arquitecto brasileno Fabio Moura Penteado...

  8. Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds.), Les Lectures de Gaston Bachelard. Index bibliographique

    OpenAIRE

    Aurosa Alison

    2012-01-01

    Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds.), Les Lectures de Gaston Bachelard. Index bibliographique (Paris, Presse Universitaire de Franche-Comté, 2011 ISBN: 978-2-84867-392) di     Aurosa Alison

  9. Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds., Les Lectures de Gaston Bachelard. Index bibliographique

    Directory of Open Access Journals (Sweden)

    Aurosa Alison

    2012-10-01

    Full Text Available Jean Libis, Fabio Ferreira, Catherine Gublin, Sarah Mezaguer (eds., Les Lectures de Gaston Bachelard. Index bibliographique (Paris, Presse Universitaire de Franche-Comté, 2011 ISBN: 978-2-84867-392 di  Aurosa Alison

  10. Marco Fabio Quintiliano y la retórica democrática

    National Research Council Canada - National Science Library

    Víctor ALONSO ROCAFORT

    2008-01-01

    ... clásicos, Marco Fabio Quintiliano. Sus propuestas enriquecerán aquellas otras que han ido a contracorriente de las visiones triunfales de la ciencia política moderna, y que desde los años cincuenta ha tenido en autores como Hannah Arendt, Sheldon Wolin, Hans G. Gadamer, Eric Voegelin o Leo Strauss a sus mayores adalides.

  11. Nii kauge, kuid nii omane Brasiilia / Antonio Claudio Carvalho ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Carvalho, Antonio Claudio

    2005-01-01

    Vestlus brasiilia kunstniku Antonio Claudio Carvalhoga 15. X, päeval pärast tema näituse avamist Kunstihoone galeriis. Kunstist, kunstnikest, endast, oma loomingust, kunsti tähendusest praeguses Brasiilias jm.

  12. Nii kauge, kuid nii omane Brasiilia / Antonio Claudio Carvalho ; interv. Reet Varblane

    Index Scriptorium Estoniae

    Carvalho, Antonio Claudio

    2005-01-01

    Vestlus brasiilia kunstniku Antonio Claudio Carvalhoga 15. X, päeval pärast tema näituse avamist Kunstihoone galeriis. Kunstist, kunstnikest, endast, oma loomingust, kunsti tähendusest praeguses Brasiilias jm.

  13. Ursamaior, by Mario Claudio: seven stars, a falling body

    Directory of Open Access Journals (Sweden)

    Mariana Caser da Costa

    2017-06-01

    Full Text Available In the year 2000, Portuguese writer Mario Claudio publishes Ursamaior, a novel that do not escape from his tendency of turning real data into fictional pieces. Together with Orion (2003, and Gemeos (2004, that book composes the “Trilogy of the Constellations”, according to Maria Theresa Abelha Alves. The first element of that triptych exposes several types of violence, among which an exhausting rape scene suffered by Jorge, the last star of Ursamaior constellation. Therefore, we will depart from that scene in order to reflect on the preponderant role of the playful element over the mourning body, basing our text on, for example, Walter Benjamin’s Origin of the German Baroque Drama. We will also focus on the intersemiotic game that establishes a dialogue between literature and other artistic languages, in this novel, notably cinema. Finally, the act of writing will be understood as a means of suturing torn souls and bodies, and also as a way of reorganizing chaos, highlighting the neobaroque characteristic of the pair mourning-game, and the self-reflection and the metalanguage as textual strategies not rarely evidenciated by mauroclaudian works.--- DOI: http://dx.doi.org/10.22409/abriluff.2017n18a411

  14. Medicine Students’ Opinions on the English Discipline. University Polyclinic "Fabio Di Celmo"

    Directory of Open Access Journals (Sweden)

    Maira Pérez Pérez

    2011-02-01

    Full Text Available Background: The present century has been characterized by a predominance of English as the only international language for medicine and science. This statement is supported by the fact that knowledge of this foreign language completes the formation of a well prepared and highly competitive graduate student. Objective: To assess the views of medicine students on the study of English as a subject in their course. Methods: A cross-sectional descriptive study, conducted during the 2009-2010 academic year that included a sample of 26 medicine students of the University Polyclinic "Fabio Di Celmo". Variables that were considered: the actual need to teach English, students’ major motivations and satisfaction level with the educational process. Results: Most students (84.6% considered it necessary to study English as part of the Medicine career. The most important motivation for its study was communication with English speaking patients, followed by the interest to consult technical literature (72.7% and 13.6% respectively. Teaching quality was assessed as excellent by almost all of the students (92.3%. Conclusions: Medical students of the University Polyclinic "Fabio Di Celmo" consider it necessary to study English, since it strongly supports their professional performance.

  15. Developing Student Critical Thinking Skills through Teaching Psychology: An Interview with Claudio S. Hutz.

    Science.gov (United States)

    McCarthy-Tucker, Sherri

    2001-01-01

    Presents an interview with Claudio S. Hutz, who is dean of Instituto de Psicologia at Universidade Federal do Rio Grande do Sul in Porto Alegre, Brazil, where he has been teaching psychology since 1977. Discusses topics such as teaching psychology in Brazil and developing critical thinking skills. (CMK)

  16. Developing Student Critical Thinking Skills through Teaching Psychology: An Interview with Claudio S. Hutz.

    Science.gov (United States)

    McCarthy-Tucker, Sherri

    2001-01-01

    Presents an interview with Claudio S. Hutz, who is dean of Instituto de Psicologia at Universidade Federal do Rio Grande do Sul in Porto Alegre, Brazil, where he has been teaching psychology since 1977. Discusses topics such as teaching psychology in Brazil and developing critical thinking skills. (CMK)

  17. Marco Fabio Quintiliano y la retórica democrática

    Directory of Open Access Journals (Sweden)

    Víctor ALONSO ROCAFORT

    2008-01-01

    Full Text Available Desde finales del siglo veinte estamos asistiendo a un resurgir de la retórica en diversos campos académicos, algo a lo que no resulta ajena la teoría política. Se debe precisar que se habla de diversas retóricas, ya se reivindiquen unos u otros autores, o se haga hincapié en determinados aspectos de la misma. Este trabajo se enmarca en una línea comprometida en revisar fundamentos sustanciales del conocimiento, la filosofía, la ética y la praxis política, en lo que algunos califican ya de retórica democrática. Desde ahí recuperamos a uno de sus grandes autores clásicos, Marco Fabio Quintiliano. Sus propuestas enriquecerán aquellas otras que han ido a contracorriente de las visiones triunfales de la ciencia política moderna, y que desde los años cincuenta ha tenido en autores como Hannah Arendt, Sheldon Wolin, Hans G. Gadamer, Eric Voegelin o Leo Strauss a sus mayores adalides.

  18. Claudio Moraga a passion for multi-valued logic and soft computing

    CERN Document Server

    Allende-Cid, Héctor

    2017-01-01

    The book is an authoritative collection of contributions by leading experts on the topics of fuzzy logic, multi-valued logic and neural network. Originally written as an homage to Claudio Moraga, seen by his colleagues as an example of concentration, discipline and passion for science, the book also represents a timely reference guide for advance students and researchers in the field of soft computing, and multiple-valued logic. .

  19. Gestalt Therapy and the Therapeutic Presence of Fritz Perls: An Interview with Claudio Naranjo

    OpenAIRE

    Ramírez Calderón, Iván; Escuela de Gestalt Claudio Naranjo Transformación Humana Colombia

    2010-01-01

    Como testigo y participe de excepción en el origen y desarrollo de la Terapia Gestalt, en esta entrevista Claudio Naranjo considera las características de esta forma de terapia, y lo hace a partir de su trabajo y de su encuentro personal con el hombre y la figura terapéutica de Fritz Perls. A lo largo de la entrevista se establece la base experiencial y los elementos del cambio terapéutico, junto con la actitud terapéutica, y la concepción holística de la persona; además se destacan los con...

  20. Gestalt Therapy and the Therapeutic Presence of Fritz Perls: An Interview with Claudio Naranjo

    Directory of Open Access Journals (Sweden)

    Iván Ramírez Calderón

    2011-01-01

    Full Text Available As exceptional witness and participant in the origin and development of the Gestalt therapy, Claudio Naranjo considers in this interview the cha- racteristics of this form of therapy, doing so from his work and his personal encounter with the man and the therapeutic figure of Fritz Perls. In the interview the experiential base and the therapeutic change elements are established, along with the therapeutic attitude, and the holistic conception of the person; also, the contrasts among academic psychology, the spiritual dimension of human beings, and the therapist’s intuition in the help rela- tionship are highlighted.

  1. Nuevos dibujos y dos lienzos inéditos de Claudio Coello

    Directory of Open Access Journals (Sweden)

    Zapata Fernández de la Hoz, Teresa

    2014-09-01

    Full Text Available Artist of great resources, always appreciated and cited with praise, Claudio Coello (1642-1693 is undoubtedly the great figure of Spanish painting in the second half of the seventeenth century. In this article a group of drawings preserved in the Madrid Casa de la Moneda (Mint and the Uffizi in Florence are attributed to the painter. Some of them are preparatory studies for secure works. Likewise presented are two unpublished paintings, one of them a splendid portrait of a member of a religious order.Artista de amplísimos recursos, siempre apreciado y citado con elogios, Claudio Coello (1642-1693 es sin duda la gran figura de la pintura española de la segunda mitad del siglo XVII. En este artículo se atribuyen al pintor un grupo de dibujos conservados en la Casa de la Moneda de Madrid y en los Uffizi, algunos preparatorios para obras seguras, a los que se añaden dos pinturas inéditas, entre ellas un espléndido retrato de un religioso.

  2. MADRIGALI GUERRIERI ET AMOROSI: O LIVRO OXÍMORO DE CLAUDIO MONTEVERDI

    Directory of Open Access Journals (Sweden)

    Maya Suemi Lemos

    2014-09-01

    Full Text Available A coletânea musical Madrigali Guerrieri et Amorosi, obra de maturidade do mais influente e revolucionário compositor do seicento, Claudio Monteverdi, se configura como materialização musical de uma poética dos contrários emblemática da estética literária maneirista e barroca. Indícios presentes na coletânea nos permitem identificar alguns dos principais marcos da genealogia desta poética dos contrários, assim como avançar hipóteses quanto ao sentido desta coletânea dentro da extensa obra musical de Monteverdi.                                 The musical collection known as Madrigali Guerrieri et Amorosi, a mature work of Claudio Monteverdi, the most influential and revolutionary composer of the seicento, represents a musical realization of a poetics of opposites which is emblematic of the Baroque and mannerist literary aesthetics. Indications present in the collection allow us to identify some of the principal landmarks of the genealogy of this poetics of opposites, as well as to present hypotheses about the meaning of this collection within the context of the extensive musical oeuvre of Monteverdi.  

  3. Medicine Students’ Opinions on the English Discipline. University Polyclinic "Fabio Di Celmo" Opinión de los estudiantes de Medicina sobre la disciplina Inglés. Policlínico Universitario “Fabio Di Celmo”

    Directory of Open Access Journals (Sweden)

    Ditza Viera Álvarez

    2011-02-01

    Full Text Available Background: The present century has been characterized by a predominance of English as the only international language for medicine and science. This statement is supported by the fact that knowledge of this foreign language completes the formation of a well prepared and highly competitive graduate student. Objective: To assess the views of medicine students on the study of English as a subject in their course. Methods: A cross-sectional descriptive study, conducted during the 2009-2010 academic year that included a sample of 26 medicine students of the University Polyclinic "Fabio Di Celmo". Variables that were considered: the actual need to teach English, students’ major motivations and satisfaction level with the educational process. Results: Most students (84.6% considered it necessary to study English as part of the Medicine career. The most important motivation for its study was communication with English speaking patients, followed by the interest to consult technical literature (72.7% and 13.6% respectively. Teaching quality was assessed as excellent by almost all of the students (92.3%. Conclusions: Medical students of the University Polyclinic "Fabio Di Celmo" consider it necessary to study English, since it strongly supports their professional performance.Fundamento: El presente siglo se ha caracterizado por un predominio de la lengua inglesa como único idioma internacional de la medicina y la ciencia. Esta afirmación se corrobora si se toma en cuenta que hoy es un hecho que el conocimiento de este idioma extranjero completa la formación de un egresado bien preparado y de alta competencia. Objetivo: Evaluar la opinión de los estudiantes de Medicina acerca del estudio del inglés como asignatura en su carrera. Métodos: Estudio descriptivo, transversal, realizado durante el curso 2009-2010 que

  4. Rio de Janeirost Tallinna, 75 kraadi Celsiuse järgi / Antonio Claudio Carvalho ; tõlk. Reet Varblane

    Index Scriptorium Estoniae

    Carvalho, Antonio Claudio

    2006-01-01

    Juhendaja Antonio Claudio Carvalho Eesti Kunstiakadeemia üliõpilastele toimunud maalimeistriklassist "Ava oma silmad" ja lõpunäitusest Eesti Kunstiakadeemia galeriis. Enne näitust näitasid üliõpilased tööd, mida nad ise pidasid parimaks, kunstikriitik Heie Treierile

  5. Rio de Janeirost Tallinna, 75 kraadi Celsiuse järgi / Antonio Claudio Carvalho ; tõlk. Reet Varblane

    Index Scriptorium Estoniae

    Carvalho, Antonio Claudio

    2006-01-01

    Juhendaja Antonio Claudio Carvalho Eesti Kunstiakadeemia üliõpilastele toimunud maalimeistriklassist "Ava oma silmad" ja lõpunäitusest Eesti Kunstiakadeemia galeriis. Enne näitust näitasid üliõpilased tööd, mida nad ise pidasid parimaks, kunstikriitik Heie Treierile

  6. The Argonaut Myth in the Novel Alla cieca by Claudio Magris

    Directory of Open Access Journals (Sweden)

    Irena Prosenc

    2012-12-01

    Full Text Available The paper analyses the disintegration of identity and fragmentation of the narrative voice in the novel Alla cieca (Blindly, 2005 by Claudio Magris. Through the metaphor of sailing, the Trieste writer explores various aspects of narration, focusing on the autobiographical narrative; furthermore, he reflects on the multiple identity of the modern ego and on the destructive force of History, whose oppression has been perpetuated in the recent periods as well. The many issues addressed by the novel are connected by the continuous presence of the Argonaut myth, evoked by numerous intertextual references to the Argonautica by Apollonius Rhodius and to the Argonautica Orphica – a title which is, in contrast to that of the Hellenistic poem, not explicitly cited in the text.

  7. La voz de Claudio Rodríguez: propuesta para una escucha crítica

    Directory of Open Access Journals (Sweden)

    Alessandro Mistrorigo

    2012-05-01

    Full Text Available By starting from Claudio Rodríguez’s recordings, this paper suggests a way of listening voice in poetry pointing out some interesting aspects and problems that arise when establishing a new encounter not just between the poet’s voice and the listener, but also between the poet’s voice and the critic. The physical voice of a poet reading aloud his own poems re-projects and restructures constituting elements of poetic language (i.e. enjambment and caesura making evident variations between published version and vocalized one. Moreover, it always has a specific tone or a particular inflection, an accent or a personal prosody that contrubute to the listener’s comprehention of the text. Through the vocal execution the text is re-evoked always in a different way within a specific time and space as well as re-given a new relationship with the subject who is listening and understanding it.

  8. Violencia y maltrato en la familia romana y sus consecuencias : la adolescencia perdida de Tiberio Claudio

    Directory of Open Access Journals (Sweden)

    Milagros Moro Ipola

    2008-01-01

    Full Text Available El maltrato psicológico es todo aquel que se ejerce contra el normal desarrollo de la personalidad de un niño. Aunque actual, es una situación que niños y adolescentes han venido sufriendo a lo largo de los siglos y cuyas consecuencias se han dejado ver, ya no sólo durante su adolescencia, sino también en la edad adulta. Uno de los casos más significativos de maltrato hacia un menor es el que sufrió el emperador Tiberio ClaudioThe psychological maltreatment is whatever is exercised against the normal development of the personality of a child. Even though it is a current situation, children and teenagers have been suffering it over the centuries and its consequences can be seen not only during the adolescence but in their manhood. One of the most significant cases of maltreatment against a kid is that one Emperor Tiberius Claudius suffered.

  9. Looking through the Myth: the Figure of the Poet in Two Works by Claudio Magris

    Directory of Open Access Journals (Sweden)

    Irena Prosenc

    2015-04-01

    Full Text Available The paper analyses the figure of the poet in two works by the contemporary Italian writer Claudio Magris: in the short prose text Lei dunque capirà (You Will Therefore Understand and the novel Alla cieca (Blindly. In both works the figure of the poet is constructed through the eyes of the other as well as through the prism of mythological narration. In Lei dunque capirà, the image of the poet is shaped by Eurydice's voice, which filters the Orpheus myth, actualising and perhaps banalizing it. The novel, on the other hand, uses the Argonauts myth, intertwined with the Odysseus and Orpheus myths, to reflect on the nature of the narrating voice. The novel questions whether autobiographical narration can at all be reliable or whether it is to be considered – along with mythological narration – as nothing more than “réclame”, representing a deformed view of personal, historical and mythological memory. Magris questions the existence of a stable narrative voice in contemporary fiction, since it appears fragmented and unsure about its own identity. Both works include myth as the central element facilitating reflection on fundamental metaliterary issues. “Looking at the Myth” thus becomes “looking through the myth”, as well as, in Eurydice's narration, looking at a reflection: “I haven't seen myself, I do not know myself. But if you tell me about this, I shall know it and will be able to narrate it”.

  10. [Claudio Costa Casaretto M.D. (1914-1999) in Revista Medica de Chile].

    Science.gov (United States)

    Goic, A

    1999-10-01

    The work of Dr. Claudio Costa Casaretto covers a broad field in the history of Medicine in Chile. He contributed with the historical aspects in the Centennial issue of Revista Médica de Chile in July, 1972. He published 85 papers in this journal in a lapse of 20 years. In his works, he investigated about medical personalities with the highest relevance for Chilean medicine such as Dr. William Blest, graduated in Edinburgh and director of the first Medicine Course in Chile in 1833, the French obstetrician Dr. Lorenzo Sazie, first Dean of the Faculty of Medicine of the University of Chile in 1843 and Dr. Eloisa Díaz, first physician graduated in Chile and South America in 1887. He published the translation from Latin of Juan Ignacio Molina's verses "Elegies to smallpox", Chilean writer and erudite of the XVIII century. He also undertook the origins of Universidad de San Felipe (1737), Universidad de Chile (1842) and Pontificia Universidad Católica de Chile (1889) and the main educational events occurred in the Faculty of Medicine of the University of Chile, during the past century. He also published about the public health situation and sanitary care during the XIX century, about the conflict between private and public teaching and other political events of the past century. The work of Dr. Costa as a whole, is a real history textbook of Chilean Medicine. Dr. Costa and Dr. Enrique Laval are the most important Chilean medical historians of the XX century.

  11. La Terapia Gestalt y la presencia terapéutica de Fritz Perls: una entrevista a Claudio Naranjo.

    OpenAIRE

    Ramírez Calderón, Iván; Escuela de Gestalt Claudio Naranjo Transformación Humana Colombia

    2010-01-01

    Como testigo y participe de excepción en el origen y desarrollo de la Terapia Gestalt, en esta entrevista Claudio Naranjo considera las características de esta forma de terapia, y lo hace a partir de su trabajo y de su encuentro personal con el hombre y la figura terapéutica de Fritz Perls. A lo largo de la entrevista se establece la base experiencial y los elementos del cambio terapéutico, junto con la actitud terapéutica, y la concepción holística de la persona; además se destacan los con...

  12. La Terapia Gestalt y la presencia terapéutica de Fritz Perls: una entrevista a Claudio Naranjo.

    OpenAIRE

    Ramírez Calderón, Iván; Escuela de Gestalt Claudio Naranjo Transformación Humana Colombia

    2010-01-01

    Como testigo y participe de excepción en el origen y desarrollo de la Terapia Gestalt, en esta entrevista Claudio Naranjo considera las características de esta forma de terapia, y lo hace a partir de su trabajo y de su encuentro personal con el hombre y la figura terapéutica de Fritz Perls. A lo largo de la entrevista se establece la base experiencial y los elementos del cambio terapéutico, junto con la actitud terapéutica, y la concepción holística de la persona; además se destacan los con...

  13. Comentario en el aula del poema «Al ruido del Duero» de Claudio Rodríguez

    Directory of Open Access Journals (Sweden)

    María Antonia MEZQUITA FERNÁNDEZ

    2009-11-01

    Full Text Available RESUMEN: En el siguiente artículo se tratará de reflejar la experiencia en un aula de Educación Primaria para acercar a los niños la figura de Claudio Rodríguez y centrarnos en un comentario de su poema «Al ruido del Duero». El colegio elegido es el «Arias Gonzalo», de Zamora. Los niños participaron activamente a la hora de aportar ideas y de comentar el texto. Claudio Rodríguez se sentía fascinado y profesaba un gran amor a su tierra, a sus costumbres y al río Duero. Consideraba que los valores más relevantes del ser humano eran la sencillez, la solidaridad y la fraternidad y deseaba unirse y fundirse, primero, con el entorno natural y, después, con los hombres. En mi opinión, la respuesta de los alumnos fue positiva, ya que captaron la esencia de los versos y demostraron, con su colaboración, que los elementos usados para motivarles habían servido. Lo dejaron patente en las cartas, dibujos y poemas que realizaron posteriormente.ABSTRACT: The following article will try to show a commentary on the poem «Al ruido del Duero» by Claudio Rodríguez, from Zamora. The school which was chosen is called «Arias Gonzalo»; it is in Zamora too. The pupils took part actively and their ideas contributed to comment the text. Claudio Rodríguez was fascinated and professed huge love for the place where he was born, the customs of his province and The Duero River. He believed that the most important human values were simplicity, solidarity and brotherhood. First of all, he wished to be bound to nature. As far as mankind is concerned, he always desired to be joined together. In my opinion, the pupils answered positively and they understood the essence of the verses. They all proved that the elements for motivating them were useful. Then, they showed it clearly by drawing pictures, writing letters and poems.

  14. Don Claudio Sánchez Albornoz. El historiador y su obra

    Directory of Open Access Journals (Sweden)

    Serafín DE TAPIA

    2009-08-01

    Full Text Available Avila fue uno de los primeros lugares de España donde se realizó una manifestación a favor de la República. Corrían los últimos días de junio de 1869 y los sectores más progresistas del país, los republicanos, habían intensificado su movilización a raíz de la Promulgación de la Constitución de 1869, que reconocía que la monarquía era la forma de gobierno de la Nación española (art. 33. En Avila dimiten nueve concejales y los que siguen en sus puestos solicitan infructuosamente armas para los Voluntarios de la Libertad1, con cuyo apoyo pensaban los regidores mantener el espíritu de La Gloriosa. Eran tiempos agitados: los ultraconservadores carlistas se vuelven a alzar en partidas, lo que mueve al Comité Republicano de Avila a solicitar, en agosto de 1869, licencia del Ayuntamiento para «crear una fuerza aparte de su mismo partido, compuesta de cien o más hombres». Se deniega la autorización y además, meses después, el Gobierno central, cada vez más moderado procede a desarmar a los Voluntarios de la Libertad, como se estaba haciendo en todo el país; enterados los regidores del hecho consumado de la disolución de las Milicias urbanas se convoca el 6 de octubre sesión extraordinaria del Ayuntamiento para examinar el asunto. Un regidor lleva la voz cantante proponiendo a sus colegas dimitir en bloque como protesta: es D. Lucio Sánchez Albornoz, ascendiente directo de D. Claudio (era su tío-abuelo. La propuesta no fue secundada y ocho días después se recibe en el Ayuntamiento un oficio del Sr. Gobernador suspendiendo de su cargo de regidor a Sánchez Albornoz e imponiéndole una multa de 20 escudos (el salario mensual de un peón «con motivo de no haberse prestado a jurar la Constitución de 1869

  15. Modelo de valoración administrativa de los recursos enfocados a los estudiantes de la Institución Educativa Fabio Vázquez Botero sede Naranjales del municipio de Dosquebradas

    OpenAIRE

    Peláez Delgado, Dayana

    2016-01-01

    La presente propuesta de investigación es una recopilación de datos e información primaria y secundaria acerca del “Modelo de valoración administrativa de los recursos enfocados a los estudiantes de la Institución Educativa Fabio Vásquez Botero sede naranjales del municipio de Dosquebradas”, donde se hizo un trabajo previo o diagnóstico en la Institución Educativa Fabio Vásquez Botero a través de información primaria y secundaria con formato de encuesta, observación directa y material bibliog...

  16. 'Don Fabio' and the taming of the three lions: the discursive construction of a foreign England manager's identity in the sports online written media

    Directory of Open Access Journals (Sweden)

    Dermot Brendan Heaney

    2013-06-01

    Full Text Available This article considers the appointment of a foreign manager to coach a national football team from the perspective of discursive identity construction. The data is comprised of three corpora of online versions of newspaper articles, each corresponding to a phase in Fabio Capello’s first two years of tenure. Reflecting current trends in Critical Discourse Analysis, qualitative close analysis is carried out on two articles from each corpus while quantitative analysis is extended across each corpus to identify salient and consistent aspects of discursive identity construction. Exploiting the multi-disciplinary basis of CDA, the data is examined in terms of transitivity, lexis (comprising vocabulary, collocation, deixis, and intertextuality, and narrative identity construction. Micro-analysis of grammatical and linguistic patterns is applied to indicate patterns in press coverage in each phase, and a corresponding overview considers how aspects of identity work diffused through each corpus cohere into general storylines.

  17. Geografía y nación. Claudio Gay y la primera representación cartográfica de Chile

    Directory of Open Access Journals (Sweden)

    Sagredo Baeza, Rafael

    2009-06-01

    Full Text Available This work considers the cartographic work that French naturalist Claudio Gay completed after he was hired by the Chilean government in 1830 to explore, recognize and study Chile’s territory and its resources. All of these made the first national cartography of the country possible. Claudio Gay’s cartographic contribution is valued in the context of the relationships between science and power and his maps are interpreted both as essential instruments for state administration and as tools for territorial integration and sovereignty purposes.

    El trabajo aborda la obra cartográfica del naturalista de origen francés Claudio Gay quién, contrado por el gobierno chileno en 1830 para explorar, reconocer y estudiar el territorio chileno y sus recursos, terminó preparando la primera cartografía de carácter nacional del país. El quehacer geográfico de Gay es apreciado en el contexto de las relaciones entre ciencia y poder, y sus mapas interpretados como un instrumento esencial de la administración estatal en cuanto herramienta para la integración territorial y el ejercicio de la soberanía.

  18. Fabio Corbisiero (a cura di, Comunità omosessuali. Le scienze sociali sulla popolazione LGBT, FrancoAngeli Editore, pp. 287

    Directory of Open Access Journals (Sweden)

    Maria Antonietta Selvaggio

    2013-10-01

    Full Text Available The book review shall examine the work Comunità omosessuali. Le scienze sociali sulla popolazione LGBT (Homosexual community. The social sciences on the LGBT population, Fabio Corbisiero (ed., offering a detailed survey of the points of view expressed by various disciplines on issues related to LGBT people’s identity and rights in a heterosexist society. It is highlighted the critical and proactive approach with which the male and female authors of the fifteen essays in the volume analyze homosexuality as a plural condition, spread and mobile of the  human existence. What that is exceeded in the theory and practice is the dichotomous homosexuality/ heterosexuality principle which for long time structured the social knowledge, ensuring an effective instrument of control and social order. Nowadays, the instance that is imposed on the planes of the knowledge and reality is that of a necessary "pluralization", without which it can’t be guaranteed a  true citizenship to people and homosexual communities.

  19. [Review of:] Context: Nature, Impact, and Role; 5th International Conference on Conceptions of Library and Information Science, CoLIS 2005, Glasgow 2005; Proceedings. Eds.: Fabio Crestani, Ian Ruthven. Berlin: Springer, 2005. xiii, 250 S., ISBN 3-540-26178-8

    OpenAIRE

    2006-01-01

    Book review of Context: Nature, Impact, and Role; 5th International Conference on Conceptions of Library and Information Science, CoLIS 2005, Glasgow 2005; Proceedings. Eds.: Fabio Crestani, Ian Ruthven. Berlin: Springer, 2005. xiii+250p., ISBN 3-540-26178-8 (pbk). This is volume 3507 of "Lecture Notes in Computer Science" (LNCS). It contains the papers of the 5th CoLIS meeting, most of them rather sophisticated, and makes an interesting reading.

  20. “Boletum medicatum”. La seta que mató al emperador Claudio / Boletum medicatum. The mushroom that killed the emperor Claudius

    Directory of Open Access Journals (Sweden)

    Joaquín Villalba Álvarez

    2009-06-01

    Full Text Available Resumen: Mucho se ha escrito a lo largo de los siglos sobre las circunstancias que rodearon la muerte del emperador romano Claudio (10 a. C. – 54 d. C.. El consenso general entre los historiadores antiguos que narran el episodio –Tácito, Suetonio y Dion Casio-, así como muchas otras referencias dispersas en la literatura latina nos llevan a pensar que su muerte se debió a una conspiración de su cuarta esposa, su sobrina Agripina, que le sirvió un plato de setas previamente envenenadas. Sin embargo, entre los estudiosos modernos hay quienes, como Grimm-Samuel, han barajado la posibilidad de que su muerte se debió a la ingesta (ya fuese premeditadamente, ya de manera accidental de setas venenosas, en concreto de la especie Amanita phalloides. Partiendo de diversos argumentos, ofrecemos nuestra opinión sobre el tema, que no difiere mucho de la que ofrecen los escritores de la Antigüedad.Summary: In the course of the centuries, many pages have been written on the circumstances surrounding the death of the Roman Emperor Claudius (10 BC – 54 AD. General agreement among ancient historians who relate us the story –Tacitus, Suetonius, Cassius Dio-, as well as the rest of scattered references in Latin literature induce us to think his death was due to his fourth wife’s conspiracy, his niece Agrippina, who served him a dish with previously poisoned mushrooms. Nevertheless, some of the scholars of our time, Grimm-Samuel for example, have considered the hypothesis that Claudius died because he ingested poisonous mushrooms (“either through criminal intent, or by sheer accident”, more specifically Amanita phalloides. Starting from different arguments, we offer our own point of view, which does not differ much from the ancient writers’ opinion.

  1. Mejoramiento de la integración sensorial en niñas y niños con discapacidad auditiva y visual de la Unidad Educativa Especial “Claudio Neira Garzón” Cuenca 2013

    OpenAIRE

    Pacheco Gutiérrez, Lourdes Verónica

    2014-01-01

    Un aula de Integración Sensorial es un espacio adaptado que se utiliza para proporcionar apoyo terapéutico positivo a los niños y niñas con discapacidad, favoreciendo la integración de sus sentidos y mejorando su calidad de vida. El presente proyecto se realizó en la Unidad Educativa Especial “Claudio Neira Garzón”, la población beneficiaria son los niños y niñas con discapacidad auditiva y visual. La propuesta básicamente se compone de tres grandes resultados los mismos que se alcanz...

  2. Incidencia de una secuencia didáctica de enfoque discursivo - interactivo en la comprensión de textos narrativos de los niños y niñas de grado preescolar de la institución educativa Fabio Vásquez Botero

    OpenAIRE

    Arbeláez Hincapié, Diana Marcela; Ramírez Villa, Yeinny Andrea

    2014-01-01

    La presente investigación cuantitativa da cuenta de la incidencia de una secuencia didáctica relacionada con los procesos de comprensión lectora en niños y niñas de la Institución Educativa Fabio Vásquez Botero del municipio de Dosquebradas. Para lograr este propósito se trabaja un diseño cuasi experimental de un grupo intacto con pre test y post test; en primer lugar, se valorar el nivel inicial de la comprensión lectora de textos narrativos, luego se implementa la secuencia didáctica enmarc...

  3. 迪普马与罗升的机电液整合之路——访迪普马全球销售总监Claudio Gazzaniga先生

    Institute of Scientific and Technical Information of China (English)

    张玲玲

    2009-01-01

    1952年以来意大利迪普马公司一直致力于液压领域的元件生产和系统集成的设计与制造。进入中国液压市场是2005年,与其它国外品牌比较起来进入中国市场较晚。但是,迪普马品牌不仅在短期之内扩大了品牌知名度还赢得了市场的认可。为此我们采访了迪普马全球销售总监Claudio Gazzaniga先生。

  4. Study of the musical dramaturgy in L'Orfeo, by Claudio Monteverdi, conducted from the tonal language of the composer : a proposal for a modern orchestration as dramaturgic appeal

    OpenAIRE

    Abel Luis Bernardo da Rocha

    2008-01-01

    Resumo: Este trabalho tem por objetivo apresentar a realização de uma PARTITURA CONTEMPORÂNEA DE EXECUÇÃO da ópera L'Orfeo - Favola in Musica, de Claudio Monteverdi, composta em 1607, apresentada aqui como uma transcrição historicamente informada, sugerindo a utilização de uma mescla de recursos e instrumentos contemporâneos combinados àqueles específicos da prática musical do repertório setecentista. Tal realização embasou-se na teoria e prática musical do século XVII. Num primeiro moment...

  5. PEREIRA, Claudio Corrêa. Minuanos/Guenoas. Os Cerritos da bacia da lagoa Mirim e as origens de uma nação pampiana. Porto Alegre: Fundação Cultural Gaúcha, 2008.

    Directory of Open Access Journals (Sweden)

    Rafael Milheira

    2012-09-01

    Full Text Available O livro publicado pelo Movimento Tradicionalista Gaúcho  –RS, intitulado:  Minuanos/Guenoas. Os Cerritos da bacia da lagoa Mirim e as origens de uma nação pampiana, de autoria de Claudio Corrêa Pereira é o resultado de sua monografia apresentada ao curso de  especialização em História da Formação Social, Política e Cultural do Rio Grande do Sul, da Universidade Católica de Pelotas. Este livro, dividido em duas partes e considerações finais, traz à tona uma temática há bastante tempo “adormecida” na arqueologia do sul do Brasil e que diz respeito às sociedades ameríndias que habitaram a região pampiana que envolve o sul do Estado do Rio Grande do Sul, o território uruguaio e o nordeste argentino. O tema diz respeito à história dos grupos Minuano/Guenoa, como ficaram conhecidos pela documentação etnohistórica e, ainda poderíamos, com a licença das terminologias utilizadas pelo autor, complementar também lembrando os grupos Charrua, que igualmente habitaram esta região, confundindo-se e mesclando-se aos primeiros ao longo da história colonial.

  6. [Claudio Galeno and the lateral ventricles].

    Science.gov (United States)

    Martínez, F; Decuadro-Sáenz, G

    2008-02-01

    Galen of Pergamon is considered one of the fathers of occidental medicine. Because of cultural and religious precepts at his time, many authors hypothesize that the anatomical concepts of Galen were derived from dissection of monkeys. In this paper, the authors analyzed the ventricular system, according to the anatomic and functional concepts described by Galen's early work. Knowing that his work was derived and or influenced from other preceding anatomists and physicians (specially Hipocrates of Cos), we present our investigation in two parts. In the first part, we present the influences of previous religious, philosophic, medical and anatomical theories over the galenic work. The "pregalenic era" can be divided in three periods: 1) the pretecnic era (ending in VI BC) in which the man have only a rudimentary knowledge of human anatomy, 2) the hellenistic science (from VI to III BC) and 3) the period comprised between III BC to Galenic period. In each of the three periods, we analyzed the neuroanatomic knowledge of the most important cultures.

  7. Täppispalkamine / Claudio Fernandez-Araoz

    Index Scriptorium Estoniae

    Fernandez-Araoz, Claudio

    2005-01-01

    10 peamist viga, mis tehakse uute töötajate tööle värbamisel ning vigade võimalikest lahendustest. Kommenteerivad Agu Vaher, Terje Tiiman ja Ille Einmann. Vt. samas: Kas teie firma vajaks uue inimese töölevärbamisel välist abi?; Midagi enamat kui vestlus - struktureeritud intervjuu; Kumba valida - armastusväärne tossike või kurjamist proff?

  8. Täppispalkamine / Claudio Fernandez-Araoz

    Index Scriptorium Estoniae

    Fernandez-Araoz, Claudio

    2005-01-01

    10 peamist viga, mis tehakse uute töötajate tööle värbamisel ning vigade võimalikest lahendustest. Kommenteerivad Agu Vaher, Terje Tiiman ja Ille Einmann. Vt. samas: Kas teie firma vajaks uue inimese töölevärbamisel välist abi?; Midagi enamat kui vestlus - struktureeritud intervjuu; Kumba valida - armastusväärne tossike või kurjamist proff?

  9. 2015年卡纳瓦罗执教时期与斯科拉里执教时期广州恒大中超联赛调研分析%The Survey of Chinese Super League with Guangzhou Evergrande ClubWhen Fabio Cannavaro Charge with Luiz Felipe Scolari Coached Period in 2015

    Institute of Scientific and Technical Information of China (English)

    卢自力

    2016-01-01

    Using literature method, video observation, mathematical statistics and comparative analysis of the 2015 season guangzhou Evergrande taobao cannavaro coaching club with luiz felipe scolari coached pe⁃riod Chinese super league match case study analysis. Results show that when fabio cannavaro charge guang⁃zhou Evergrande injury is more, the squad is weak, the face of strong attack effect is significantly reduced, to concede more is the main reason for the lower wins;Luiz felipe scolari coached period guangzhou heng brigade squad is relatively perfect, play more mature, there is a decrease in the overall offensive ability, though, but defense quality and effect is improved significantly, the team's ability to control the game signifi⁃cantly enhanced is the root cause of the defending team success.%运用文献资料法、录像观察法、数理统计法和比较分析法对2015赛季广州恒大淘宝俱乐部卡纳瓦罗执教时期与斯科拉里执教时期中超联赛比赛情况进行调研分析。结果发现,卡纳瓦罗执教时期广州恒大伤病较多,阵容较为薄弱,面对强队时进攻效果明显降低,失球数较多是其获胜率较低的主要原因;斯科拉里执教时期广州恒大队阵容较为完善,打法更加成熟,整体进攻能力虽有下降,但防守质量和防守效果明显提升,球队对比赛的控制能力明显增强是球队成功卫冕的根本原因。

  10. Fabio Targhetta, Serenant et illuminant. I cento anni della SEI

    Directory of Open Access Journals (Sweden)

    Michel Manson

    2012-11-01

    Full Text Available La SEI, qui édite ce livre consacré à son histoire, est la Società Editrice Internazionale. Il y a six chapitres, qui correspondent à un plan chronologique : les origines de la SEI (Don Bosco et les Salésiens, de 1862 au début du xxe siècle, le passage d’une imprimerie de la Bonne Presse à une entreprise éditoriale, fondée le 31 juillet 1908 (débuts du xxe siècle et première guerre mondiale, l’entre-deux-guerres, les années 1950 et 1960, la SEI et l’école de masse, la SEI dans le nouveau mi...

  11. Reseña: Birocco, Carlos María & Cacciatore, Luis Claudio. El despegue del desarrollo tecnológico en la Provincia de Buenos Aires: industria saladeril, aprovechamiento del agua subterránea y mensuración de la tierra en el siglo XIX.

    Directory of Open Access Journals (Sweden)

    Facundo Roca

    2016-09-01

    Full Text Available El presente trabajo constituye una reseña de la obra El despegue del desarrollo tecnológico en la Provincia de Buenos Aires: industria saladeril, aprovechamiento del agua subterránea y mensuración de la tierra en el siglo XIX, de Carlos María Birocco y Luis Claudio Cacciatore. En esta reseña se realiza una revisión crítica del libro, identificando las fuentes y métodos empleados por los autores, las hipótesis centrales de la obra y los principales aportes y contribuciones al estudio del tema abordado. La obra comentada consiste en una investigación centrada en tres aspectos específicos del desarrollo científico-tecnológico de la segunda mitad del siglo XIX: la regulación de la actividad saladeril, el desarrollo de la hidrología y la mensuración y castración de tierras.

  12. Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report

    OpenAIRE

    Manzon L; Ettorre E; Viscogliosi G; Ippoliti S; Filiaci F; Ungari C; Fratto G; Agrillo A.

    2014-01-01

    Licia Manzon,1 Evaristo Ettorre,1 Giovanni Viscogliosi,1 Stefano Ippoliti,1 Fabio Filiaci,2 Claudio Ungari,2 Giovanni Fratto,1 Alessandro Agrillo2 1Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, 2Department of Odontology and Maxillofacial Surgery, “Sapienza” University, Rome, Italy Abstract: Bisphosphonate-related osteonecrosis of the jaw (BRONJ) is an adverse drug reaction described as the progressive destruction and deat...

  13. Claudio Gigante - Dirk Vanden Berghe (eds., Il romanzo del Risorgimento

    Directory of Open Access Journals (Sweden)

    Marina Polacco

    2014-05-01

    Full Text Available A  lungo il dibattito storiografico sul Risorgimento è stato dominato dalla contrapposizione tra la retorica patriottica (la celebrazione della nascita della patria, il culto dei martiri e degli eroi risorgimentali e la denuncia dei limiti e delle inadempienze del processo di unificazione (la critica del Risorgimento come rivoluzione mancata, il riconoscimento della sostanziale immobilità delle strutture di potere, la questione meridionale. Parallelamente, in campo specificamente letterario il filone d’indagine più praticato è stato quello relativo alla narrativa ‘antirisorgimentale’ – sulla scia della celebre definizione di ‘romanzo antistorico’ coniata da Spinazzola a proposito di tre testi fondamentali nella rappresentazione del periodo storico in questione (e cioè I Vicerè, I vecchi e i giovani e Il gattopardo.

  14. Laenude lõksus / Dag Kirsebom, Claudio Zucchelli

    Index Scriptorium Estoniae

    Kirsebom, Dag

    2008-01-01

    Majandussurutise tingimustes ning olukorras, kus üle saja protsendi Eesti aastasest sisemajanduse kogutoodangust moodustavad laenud, peavad eestlased hakkama säästlikumalt elama, isiklikku finantsolukorda aitab kontrolli all hoida kuueelarve koostamine

  15. Laenude lõksus / Dag Kirsebom, Claudio Zucchelli

    Index Scriptorium Estoniae

    Kirsebom, Dag

    2008-01-01

    Majandussurutise tingimustes ning olukorras, kus üle saja protsendi Eesti aastasest sisemajanduse kogutoodangust moodustavad laenud, peavad eestlased hakkama säästlikumalt elama, isiklikku finantsolukorda aitab kontrolli all hoida kuueelarve koostamine

  16. LHC highlights from ATLAS - FRAPWS2016 conference - Claudio Luci

    CERN Document Server

    Luci, Claudio; The ATLAS collaboration

    2016-01-01

    I am going to give a talk about highlight from ATLAS. The conference is FRAP2016, it is a conference of astrophysics. My talk is the third one oon the first day, after a general talk and one about dark matter search at colliders (given by someone does not working in atlas or cms). There is not a talk given by a colleague from cms, so mine is the only one about lhc. I have prepared my slides thinking about a "general" public and not for a specialized audience like the one we use to give talks. I have 30 minutes, maybe I have too many slides but I can easily keep the ones about dark matter if I am going to run late.

  17. Fabio Vighi, Sexual difference in European Cinema.The curse of Enjoyment

    Directory of Open Access Journals (Sweden)

    Emanuela Patti

    2011-11-01

    Full Text Available Seguendo un approccio critico che, sulla scia del pensiero di Slavoj Zižek, esplora il profondo legame tra finzione cinematografica e psicanalisi, va subito detto che questo saggio aggiunge un fondamentale tassello nel filone dei recenti sviluppi della teoria lacaniana offrendo una radicale rilettura del cinema europeo del Dopoguerra. Intesa come schermo della fantasia, la narrativa filmica è qui assunta come (pretesto per esplorare il tema della differenza sessuale (sexual difference quale paradigma di riferimento alla distanza incolmabile tra uomo e donna e svelare la discrepanza e i legami tra la realtà e il Reale del godimento, da cui deriva la provocatoria tesi lacaniana “non c’è rapporto sessuale”. Rohmer, Fellini, Buñuel, Pasolini, Almodóvar, Antonioni e Bergman sono solo alcuni dei registi attraverso i quali Vighi analizza i diversi modi di concepire il vuoto traumatico che alimenta il desiderio tentando di identificare, con sguardo politico, il nocciolo represso che struttura la nostra esperienza come soggetti immersi in uno specifico contesto socio-simbolico.

  18. http://www.utgjiu.ro/revista/ec/pdf/2009-01/14_MASINI_FABIO.pdf

    Directory of Open Access Journals (Sweden)

    Odzaklieska Dragica

    2009-05-01

    Full Text Available Investment companies are exploring the best opportunities on financial markets for financial instruments transactions in order to optimize the portfolio structure and to diversify the risk. Trading the financial derivatives is assumed to be one of the most efficient methods to increase the returns and minimize the risk while managing the portfolio. Financial derivatives transactions turn into the most popular mechanism aimed at increasing the portfolio performances. Hence, the purpose of this paper is to explore the financial futures characteristics and types, as well as the impact of the futures strategies on the risk and portfolio returns.

  19. ABOUT OGLING: THE SET TABLE IN “MY PORTO”, BY MÁRIO CLAUDIO

    Directory of Open Access Journals (Sweden)

    Mariana Caser da Costa

    2014-04-01

    Full Text Available Mario Claudio’s bibliographic production, which spans varied genders, re­markably plays with literature’s ability of representing. In Meu Porto (My Porto, work published in 2001, the Portuguese writer fosters a walk around the burgh through an intersemiotic trip which invites different artistic lan­guages and ways of expression to the text, in a richly illustrated edition, with images based on the city he was born, that intends to reveal, through the biases of Porto’s landscape, art, mysticism, cultural and culinary tripeira tradition, a kind of a city report. What is interesting about the defended ideas in this article is how the author recreates his Porto by the pathway of the food, of the Portuguese rich table, by matching it with important peo­ple who had been in town. Therefore, literature can be read by a subjective speech which, highlighting traditional aspects of Portuguese culture, espe­cially food, reveals, in this dialog between the letters and the culinary art, images, flavors, and palatable stories to the taste of the text.

  20. Silicon alleviates Cd stress of wheat seedlings (Triticum turgidum L. cv. Claudio) grown in hydroponics.

    Science.gov (United States)

    Rizwan, M; Meunier, J-D; Davidian, J-C; Pokrovsky, O S; Bovet, N; Keller, C

    2016-01-01

    We investigated the potential role of silicon in improving tolerance and decreasing cadmium (Cd) toxicity in durum wheat (Triticum turgidum L. durum) either through a reduced Cd uptake or exclusion/sequestration in non-metabolic tissues. For this, plants were grown in hydroponic conditions for 10 days either in presence or absence of 1 mM Si and for 11 additional days in various Cd concentrations (0, 0.5, 5.0 and 50 μM). After harvesting, morphological and physiological parameters as well as elemental concentrations were recorded. Cadmium caused reduction in growth parameters, photosynthetic pigments and mineral nutrient concentrations both in shoots and roots. Shoot and root contents of malate, citrate and aconitate increased, while contents of phosphate, nitrate and sulphate decreased with increasing Cd concentrations in plants. Addition of Si to the nutrient solution mitigated these adverse effects: Cd concentration in shoots decreased while concentration of Cd adsorbed at the root cell apoplasmic level increased together with Zn uptake by roots. Overall, total Cd uptake decreased in presence of Si. There was no co-localisation of Cd and Si either at the shoot or at the root levels. No Cd was detected in leaf phytoliths. In roots, Cd was mainly detected in the cortical parenchyma and Si at the endodermis level, while analysis of the outer thin root surface of the plants grown in the 50 μM Cd + 1 mM Si treatment highlighted non-homogeneous Cd and Si enrichments. These data strongly suggest the existence of a root localised protection mechanism consisting in armoring the root surface by Si- and Cd-bearing compounds and in limiting root-shoot translocation.

  1. Ergonomic analysis of workplaces in the iron casting industrial pole in Claudio, Minas Gerais--Brazil.

    Science.gov (United States)

    Mottin, Artur Caron; de Miranda, Carlos A Silva; Pagnan, Caroline Salvan; Monken, Olavo Pena

    2012-01-01

    Brazil is currently recognized as the 10th largest producer of castings, and the city of Cláudio, MG is known worldwide as the "Greatest foundry and metallurgical pole in Latin America", with more than 80 companies. However, this large number of enterprises and increasing investments in product development has demanded an increase in manpower and working hours of workers in the sector, proportionally increasing the incidence of occupational related health problems like RSI (repetitive strain injury), WMSDs (work-related musculoskeletal disorders) and industrial accidents. This article aims to characterize the industry from previously conducted case studies to relate the main causes of occupational diseases and outline possible interventions through design, showing how this tool can contribute to improve the working environment, workplace, tools and equipment through ergonomics adjustments.

  2. Anna Maria Lorusso – Claudio Paolucci – Patrizia Violi (eds., Narratività. Problemi, analisi, prospettive

    Directory of Open Access Journals (Sweden)

    Marco Mondino

    2014-05-01

    Full Text Available La semiotica ha condotto la sua ricerca su forme testuali diverse considerando la narratività come il principio organizzatore di qualsiasi tipo di discorso e come vera e propria ipotesi interpretativa della cultura in generale. Un romanzo, una pubblicità, un’immagine, una città, una fotografia, una campagna di marketing, costituiscono vere e proprie configurazioni di senso che si manifestano attraverso diverse sostanze espressive e possono essere studiate come veri e propri testi analizzandone i modi di funzionamento, le stratificazione, le trasformazioni interne e le traduzioni in testi ulteriori. Non si tratta di una mera applicazione di una griglia teorica ad oggetti diversi, con il rischio di leggere indifferentemente le stesse cose ovunque, critica che è stata spesso mossa alla semiotica, piuttosto siamo in presenza di uno sguardo analitico in grado di costruire ipotesi interpretative proprio a partire dalla nozione di narratività che rappresenta il modo attraverso cui la semiotica arriva a concettualizzare il senso. La semiotica è per sua natura comparativa e trasversale e la sua specificità consiste nel guardare ad oggetti diversi facendone emergere di volta in volta le regole di funzionamento. 

  3. RESPUESTA TÉRMICA DEL INVERNADERO DE LA ESTACIÓN EXPERIMENTAL FABIO BAUDRIT MORENO, ALAJUELA, COSTA RICA

    Directory of Open Access Journals (Sweden)

    Alberto Jos\\u00E9 L\\u00F3pez-L\\u00F3pez

    2014-01-01

    Full Text Available El objetivo de este trabajo fue simular la respuesta de la temperatura interna de un invernadero, con el fin de evaluar su comportamiento térmico en función de los requerimientos del cultivo. El modelo se validó con información de un pe - riodo de cuatro meses segregado en dos intervalos (diciembre 2009 y agosto, setiembre y octubre 2010. Este considera la interacción de los cultivos, así como las condiciones ambien - tales externas como radiación, temperatura, humedad relati - va, velocidad y dirección del viento. La temperatura interna se comparó con la óptima recomendada en la literatura para chile dulce ( Capsicum annuum , tomate ( Solanum lycopersi - cum y melón ( Cucumis melo . Los resultados obtenidos pre - sentan un valor de la raíz del error medio cuadrático relativo para la temperatura simulada de 2,99% y 4,69% para cada intervalo estudiado. Esto demuestra que es posible predecir la respuesta térmica del invernadero y si su localización, diseño y aditamentos operativos son adecuados para el o los cultivos deseados. La metodología permitió evaluar las instalaciones para el desarrollo de diferentes cultivos, además, es aplicable para evaluar la factibilidad técnica de implementar mejoras en el diseño y el equipamiento, para alcanzar las condiciones óptimas requeridas por los cultivos específicos. Se concluye que el invernadero, bajo las condiciones actuales de opera - ción, es adecuado para el cultivo del melón, en menor condi - ción para el chile y del todo no es recomendable, en ciertas épocas del año, para el tomate

  4. A note of thanks

    Directory of Open Access Journals (Sweden)

    Stefania Boccia

    2013-12-01

    Full Text Available The editors-in-chief, editors, members of the editorial board and publisher of Epidemiology, Biostatistics and Public Health wish to express their sincere gratitude to the referees of the articles considered for the 2013 volume of the Journal. Giuseppe Arbia Fabio Barbone Joana Bastos Stefania Boccia Anna BossiSilvio BrusaferroChiara CadedduCaterina CaminitiGiovanni CapelliGuido CitoniGianfranco DamianiAntonio De BelvisEmma De FeoElisabetta De VitoChiara de WaureDomitilla Di ThieneAna DuarteBruno Federico Monica Ferraroni Alessandra Frustaci Carlotta Galeone Silvano Gallus Maurizio Genuardi Guglielmo Giraldi Maria Rosaria Gualano Carolina Ianuale Farhad Islami Giuseppe La Torre Patrizia Laurenti Laura Lauria Carlo La Vecchia Emanuele Leoncini Alice Mannocci Walter Mazzucco Silvia Miccoli Cristina Montomoli Eva Negri Nicola Nicolotti Caterina Palazzo GianCarlo Paradisi Patrizio Pasqualetti Claudio Pelucchi Brunella Posteraro Delphine Praud Gianluigi Quaranta Luca Sbrogiò Benedetto Simone Giuliana Solinas Maria Lucia Specchia Annamaria Tortorano Fabio TuroneBrigid UnimMaria Assunta Veneziano Francesco Vitale Antonella Zambon Alessandro Zanetti.

  5. Silicon alleviates Cd stress of wheat seedlings (Triticum turgidum L. cv. Claudio) grown in hydroponics

    DEFF Research Database (Denmark)

    Rizwan, M.; Meunier, J. D.; Davidian, J. C.

    2016-01-01

    days either in presence or absence of 1 mM Si and for 11 additional days in various Cd concentrations (0, 0.5, 5.0 and 50 μM). After harvesting, morphological and physiological parameters as well as elemental concentrations were recorded. Cadmium caused reduction in growth parameters, photosynthetic...... pigments and mineral nutrient concentrations both in shoots and roots. Shoot and root contents of malate, citrate and aconitate increased, while contents of phosphate, nitrate and sulphate decreased with increasing Cd concentrations in plants. Addition of Si to the nutrient solution mitigated these adverse...

  6. Registro sintético de uma vida: entrevista com Fábio Alves dos Santos (Synthetic record of a life - Interview with Fabio Alves dos Santos.

    Directory of Open Access Journals (Sweden)

    Fábio Alves dos Santos

    2013-12-01

    Full Text Available Fábio Alves dos Santos (1954-2013 cursou Pedagogia, Ciências Sociais e Teologia, era Especialista em Filosofia da Religião (PUC Minas, Advogado (PUC Minas e Mestre em Direito Constitucional (UFMG. Lecionou na PUC Minas como professor de Cultura Religiosa e depois como professor no Curso de Direito, atuando principalmente no Serviço de Assistência Judiciária – SAJ, especialmente cuidado de causas populares como as da ASMARE (Associação dos Catadores de Papel, Papelão e Material Reaproveitável de Belo Horizonte, da Pastoral de Rua, da Pastoral Carcerária, de movimentos de “Sem Casa”, de ocupações e tantos outros grupos. Sua primeira publicação foi “Começo de mundo novo: sofrimento, luta e vitória dos posseiros de Santana dos Frades”, Sergipe, numa versão popular em 1981 e outra pela Editora Vozes (1990. Fruto de sua dissertação de mestrado, Fábio publicou o livro “Direito Agrário: política fundiária no Brasil (1995. Em 2001 saiu seu último livro, uma coletânea de artigos publicados em diversos jornais: “Em defesa da vida”. Num artigo em Horizonte (2004, juntamente com o advogado, amigo e colega Prof. Cristiano de Melo Bastos, discutiu “A prática jurídica na missão da PUC Minas”. Fábio sofria de grave problema de visão há mais de 15 anos. Quase ficou cego depois de diversas cirurgias de miopia. Isso, porém, não o impedia de seguir seu constante compromisso com as lutas populares. Na última entrevista que concedeu, menos de um mês antes de sua morte (19 de outubro de 2013, depois de duro sofrimento de quase dois anos, no tratamento de um câncer no pâncreas, conta um pouco de sua vida, sua luta e sua percepção de várias realidades, especialmente da Igreja e da pastoral. Militante formado na Teologia da Libertação, de profunda espiritualidade, marcada por traços da religiosidade popular nordestina e comprometida com a libertação, Fábio Alves também buscou em sua vida abrir-se à teologia do pluralismo religioso, especialmente com o Santo Daime, em cuja tradição religiosa chegou a ser “fardado”, mantendo uma profunda atitude espiritual aberta ao diálogo inter-religioso.

  7. Bisphosphonate therapy and osteonecrosis of the jaw complicated with a temporal abscess in an elderly woman with rheumatoid arthritis: a case report

    Directory of Open Access Journals (Sweden)

    Manzon L

    2014-08-01

    Full Text Available Licia Manzon,1 Evaristo Ettorre,1 Giovanni Viscogliosi,1 Stefano Ippoliti,1 Fabio Filiaci,2 Claudio Ungari,2 Giovanni Fratto,1 Alessandro Agrillo2 1Department of Cardiovascular, Respiratory, Nephrologic, Anesthesiologic and Geriatric Sciences, 2Department of Odontology and Maxillofacial Surgery, “Sapienza” University, Rome, Italy Abstract: Bisphosphonate-related osteonecrosis of the jaw (BRONJ is an adverse drug reaction described as the progressive destruction and death of bone tissue of the mandible or maxilla, in the course of bisphosphonate therapy. Orally administered bisphosphonates, widely used for the treatment of osteoporosis, are rarely associated with BRONJ. Instead, the risk greatly increases whether the patient is concomitantly taking steroid and/or immunosuppressant agents. The aims of this paper are to briefly discuss the evidence of the associations between bisphosphonate therapy and BRONJ, and the effects of co-occurring factors such as the presence of rheumatoid arthritis, dental surgery, and concomitant corticosteroid therapy. In particular, we present the case of an elderly woman with BRONJ suffering from rheumatoid arthritis, with a recent dental extraction and with a very unusual complication: a temporal abscess, who was successfully treated. Keywords: bisphosphonate-related osteonecrosis of the jaw, BRONJ, adverse reaction, steroidsA Letter to Editor has been received and published for this article

  8. LOMNITZ, Claudio. Los orígenes de nuestra supuesta homogeneidad: breve arqueología de la unidad nacional en México, p.17-36.

    OpenAIRE

    Lomnitz, Claudio

    2012-01-01

    Como a ideia de que o mexicano é membro de uma raça tornou-se legítima e popular? Este ensaio encara esta pergunta num marco comparado, observando desde o início, que a racionalização da identidade nacional - isto é, que a naturalização das diferenças nacionais - é uma estratégia comum, especialmente em estados demasiado frágeis para pretender formar uma identidade nacional coletiva a partir da igualização da lei. Contudo, o caso mexicano tem características pouco comuns, já que no México a i...

  9. El proyecto historiografico de Claudio Aquaviva y la construccion de la historia de la compania de Jesus en la nueva Espana a principios del siglo XVII

    National Research Council Canada - National Science Library

    Alcantara Bojorge, Dante A

    2009-01-01

    .... La orden deseaba contar con una historia pormenorizada de los diferentes lugares donde se habia establecido, asi como de sus provincias, con el objeto de elaborar la historia "general" del instituto...

  10. Ancora su Hölderlin e gli scrittori di lingua italiana (da Giosue Carducci a Fabio Pusterla. In appendice: Giosue Carducci: [Achille]. Ms. Casa Carducci, Bologna, Cart. II, 56, 1r.

    Directory of Open Access Journals (Sweden)

    Giovanna Cordibella

    2014-06-01

    Full Text Available A discussion of the long-term “Hölderlinism” of Italian poets, starting from Vigolo’s essay on Hölderlin and the music (1966, moving back to Carducci’s translations, with a critical edition of his version of Hölderlin’s Achill (1874, see the leaf reproduced in the appendix, and concluding with a look at later Italian poets up to Pusterla (2004.

  11. Accelerated ischemic vascular retinopathy after intravitreally injected bevacizumab for central retinal vein occlusion in elderly patients

    Directory of Open Access Journals (Sweden)

    Isola V

    2013-03-01

    Full Text Available Vincenzo Isola,1 Alfredo Pece,1,2 Claudio Massironi,1 Simone Reposi,1 Fabio Dimastrogiovanni11Department of Ophthalmology, Melegnano Hospital, 2Fondazione Retina 3000, Milano, ItalyBackground: Ischemic changes in the retinal circulation are an uncommon but severe adverse vascular reaction to intravitreal bevacizumab (Avastin®, Genentech, San Francisco, CA, USA/Roche, Basel, Switzerland for central retinal vein occlusion (CRVO. In the two cases reported here, ischemic changes in the retina vasculature following intravitreal bevacizumab for CRVO were observed with the aim of describing the clinical and angiographic features of these changes.Methods: Two elderly patients with recent-onset CRVO received one off-label intravitreal injection of bevacizumab 0.05 mL/1.25 mg.Results: In Case 1, the patient's pre-treatment visual acuity was 20/400. At 3 weeks post injection, the patient could count fingers at a distance of 1 ft (30 cm and fluorescein angiography showed reduction in intraretinal hemorrhages and areas of retinal non-perfusion. However, at 6 weeks these were markedly increased compared with those seen in the photograph taken 3 weeks after treatment. In Case 2, the patient's pre-treatment visual acuity was 20/200. At 1 month post injection, vision had decreased to 20/400 and fluorescein angiography showed severe macular ischemia with a remarkable capillary dropout throughout the macula.Conclusion: Ischemic retinal injury may be an uncommon but severe adverse vascular reaction to intravitreal bevacizumab for CRVO. Although progression of retinal ischemia in CRVO could be observed shortly after intravitreal bevacizumab, whether this is a drug- or procedure-related effect or part of the natural history of the condition remains uncertain.Keywords: Avastin, ischemia, macular infarction, intraretinal hemorrhage, retinal non-perfusion

  12. A correspondência de Cláudio Manuel da Costa dirigida aos acadêmicos Renascidos: informes de uma sociedade letrada = The correspondence of Claudio Manuel da Costa to Renascidos academic: information of a scholarly society

    Directory of Open Access Journals (Sweden)

    Moraes, Carlos Eduardo Mendes de

    2014-01-01

    Full Text Available Pretende-se discutir o tipo de correspondência produzida por Cláudio Manuel da Costa, na condição de membro da Academia Brasílica dos Renascidos, e comentá-la à luz da retórica antiga, apropriada pelos letrados entre os séculos XVI e XVIII como expressão modelar. Por intermédio desses documentos, comprovam-se a filiação do poeta à prática do academicismo, apresentam-se indícios de sua biografia e do domínio de dois estilos de escrita: a poética, estilo pelo qual é conhecido; e a acadêmica, empregada no exercício de suas atribuições nas associações letradas, confirmando-se suas ações tanto no quadro político quanto intelectual da época

  13. Estudio crítico-textual del libro III de NA de Claudio Eliano: normativismo y cuestiones de método para la edición de la obra

    Directory of Open Access Journals (Sweden)

    Manuela García Valdés

    2007-12-01

    Full Text Available The authoress of this paper develops a critical study on the main debatable passages of the text of the third book of De natura animalium (NA by Aelian. (III 2. 60.20-24; 3. 60.27; 18. 67.12-13; 21. 68.1; 22. 69.7-10; 23. 69.17-20; 26. 71.23; 26. 71.28-9; 38. 75.29; 42. 77.15; 44. 77.27. In the analysis she attempts to demonstrate, on the one hand, that the language of Aelian is still very poorly known, and how it is necessary to eliminate the conjectures and the alterations which had been arbitrarily made by earlier critics, and to prepare an edition of this work in order to understand well many key passages of his work. On the other hand, she exposes and applies the Textkritisch method, as the koiné literary texts need a rigourous and differenciated treatment that takes into account the period’s literary vogue, the evolution and language uses, namely in the phonetic, morphological and syntactic peculiarities of late Greek prose together with the author’s usage. Despite all those considerations, Aelian’s works has usually been judged and analysed through classical Greek standards. This research is a new contribution to the knowledge of the language of Aelian, of postclassical Greek and of ecdotics for Greek texts of the imperial period.

  14. Compact Solar Combisystem for an Apartment Building

    National Research Council Canada - National Science Library

    Bolonina, Alona; Rochas, Claudio; Kibure, Inese; Rosa, Marika; Blumberga, Dagnija

    2010-01-01

    ... _________________________________________________________________________________ Volume 4 29 Compact Solar Combisystem for an Apartment Building Alona Bolonina, Institute of Energy Systems and Environment, Riga Technical University, Claudio...

  15. Eesti Filharmoonia Kammerkoor esitab Monteverdi muusikat

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas

  16. Laulud armastusest ja sõjast / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas

  17. Eesti Filharmoonia Kammerkoor esitab Monteverdi muusikat

    Index Scriptorium Estoniae

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas

  18. Laulud armastusest ja sõjast / Kersti Inno

    Index Scriptorium Estoniae

    Inno, Kersti, 1954-

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas

  19. Tuning the cytotoxic properties of new ruthenium(III) and ruthenium(II) complexes with a modified bis(arylimino)pyridine Schiff base ligand using bidentate pyridine-based ligands : Topical issue in honor of Ivano Bertini. Guest editors Lucia Banci, Claudio Luchinat

    NARCIS (Netherlands)

    Garza-Ortiz, Ariadna; Maheswari, Palanisamy Uma; Lutz, Martin; Siegler, Maxime A.; Reedijk, Jan

    2014-01-01

    Synthesis, spectroscopy, characterization, structures, and cytotoxicity studies of 2,6-bis(2,6-diisopropylphenyliminomethyl)pyridine (LLL) ruthenium compounds are described. The starting compound [RuCl3(LLL)] has been fully characterized using IR spectroscopy, UV-vis spectroscopy, electrospray

  20. Tuning the cytotoxic properties of new ruthenium(III) and ruthenium(II) complexes with a modified bis(arylimino)pyridine Schiff base ligand using bidentate pyridine-based ligands : Topical issue in honor of Ivano Bertini. Guest editors Lucia Banci, Claudio Luchinat

    NARCIS (Netherlands)

    Garza-Ortiz, Ariadna; Maheswari, Palanisamy Uma; Lutz, Martin; Siegler, Maxime A.; Reedijk, Jan

    2014-01-01

    Synthesis, spectroscopy, characterization, structures, and cytotoxicity studies of 2,6-bis(2,6-diisopropylphenyliminomethyl)pyridine (LLL) ruthenium compounds are described. The starting compound [RuCl3(LLL)] has been fully characterized using IR spectroscopy, UV-vis spectroscopy, electrospray ioniz

  1. Diccionarios dialectales

    Directory of Open Access Journals (Sweden)

    Jaime Jaramillo Escobar

    2007-10-01

    Full Text Available Diccionario enciclopédico afrocolombiano. Afroamericanismos y africanismos. Fabio Teolindo Perea Hinestroza. Edición del autor, Impresión: Alto Vuelo Comunicaciones, Quibdó, 2006, 438 págs., il.

  2. Muusika saab rõivasteks

    Index Scriptorium Estoniae

    2003-01-01

    Itaalia professori Fabio Sartorelli teaduseksperimendist tõlkida muusikalised noodid ja rütmid mustrite, triipude ja värvide keelde ja kanda need kangale. Itaalia firma Paul & Shark rõivakollektsioonist "Kanna muusikat, mis sulle meeldib"

  3. Caracterizacion del desarrollo y absorcion de nutrimentos del hibrido de maiz HC-57

    National Research Council Canada - National Science Library

    Fallas, Roger; Bertsch, Floria; Echandi, Carlos; Henriquez, Carlos

    2011-01-01

    En la Estacion Experimental Agricola Fabio Baudrit Moreno, Alajuela, Costa Rica se realizo un ensayo con el objetivo de determinar la absorcion de nutrimentos por parte del hibrido comercial de maiz HC-57...

  4. Muusika saab rõivasteks

    Index Scriptorium Estoniae

    2003-01-01

    Itaalia professori Fabio Sartorelli teaduseksperimendist tõlkida muusikalised noodid ja rütmid mustrite, triipude ja värvide keelde ja kanda need kangale. Itaalia firma Paul & Shark rõivakollektsioonist "Kanna muusikat, mis sulle meeldib"

  5. Hemicrania continua- building on experience and clinical science

    Science.gov (United States)

    2014-01-01

    This is a reply letter to Letter to the ‘Editor Hemicrania continua: towards a new classification?’ Fabio Antonaci and Ottar Sjaastad The Journal of Headache and Pain Citation: 2014, 15:8. PMID:24524422

  6. Muusikauudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2014-01-01

    Lühisõnumeid maailmast: Claudio Abbado (1933-2014). Kuldne Grammy eesti muusikutele. Moskva Suure Teatri muusikajuhiks sai Tugan Sokhiev. Milwaukees röövitud stradivaarius leitud. "Jaapani Beethoveniks" nimetatud Mamoru Samuragochil oli variautor

  7. Anneli Remme soovitab : Armastuse ja sõja laulud / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas, Euroraadio kontsert 29. jaan. Tallinna Metodisti kirikus

  8. Anneli Remme soovitab : Armastuse ja sõja laulud / Anneli Remme

    Index Scriptorium Estoniae

    Remme, Anneli, 1968-

    2008-01-01

    Eesti Filharmoonia Kammerkoori ja Helsingi Barokkorkestri kontserdist Claudio Monteverdi loominguga 25. jaan. Rakvere Gümnaasiumis, 26. jaan. Tartu Jaani kirikus ja 27. jaan. Tallinnas Mustpeade majas, Euroraadio kontsert 29. jaan. Tallinna Metodisti kirikus

  9. Muusikauudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2014-01-01

    Lühisõnumeid maailmast: Claudio Abbado (1933-2014). Kuldne Grammy eesti muusikutele. Moskva Suure Teatri muusikajuhiks sai Tugan Sokhiev. Milwaukees röövitud stradivaarius leitud. "Jaapani Beethoveniks" nimetatud Mamoru Samuragochil oli variautor

  10. Nanobiotechnology in energy, environment and electronics methods and applications

    CERN Document Server

    Nicolini, Claudio

    2015-01-01

    Introduction: Present Challenges and Future Solutions via Nanotechnology for Electronics, Environment and Energy; Claudio NicoliniPart A: MethodsInfluence of Chromosome Translocation on Yeast Life Span: Implications for Long-Term Industrial Biofermentation; Jason Sims, Dmitri Nikitin, and Carlo V. BruschiPulsed Power Nanotechnologies for Disintegration and Breaking Up of Refractory Precious Metals Ores; Valentin A. Chanturiya and Igor Zh. BuninModeling of Software Sensors in Bioprocess; Luca Belmonte and Claudio NicoliniN

  11. Exhibition

    CERN Multimedia

    Staff Association

    2014-01-01

      Parallels vision Astronomical subjects which evoke extrasensory kinetic visions Alberto Di Fabio From 8 to 10 October, CERN Meyrin, Main Building In the framework of Italy@cern, the Staff Association presents Alberto Di Fabio. Di Fabio’s work is inspired by the fundamental laws of the physical world, as well as organic elements and their interrelation. His paintings and works on paper merge the worlds of art and science, depicting natural forms and biological structures in vivid colour and imaginative detail. For all additional information: staff.association@cern.ch | Tel: 022 767 28 19

  12. La Costituzione Islandese: storia ed evoluzione

    Directory of Open Access Journals (Sweden)

    Fabio Quartino

    2011-03-01

    Full Text Available "La Costituzione Islandese: storia ed evoluzione" is a degree thesis defended on 15th July 2009 by Fabio Quartino under the supervision of Prof. Andrea Canepa of the University of Genoa, Italy. It offers an extensive overview of Icelandic history aimed at finding out the roots of the nation's constitutional order, which is currently in the process of being revised by the first ever elected constitutional assembly in the life of the country. Fabio Quartino's work wishes to be a source of useful information for Italian-speaking scholars who have an interest in Iceland's constitutional history and may not have access to comprehensive overviews in their native tongue.

  13. 5th National Congress of the Italian Society of Physiotherapy

    Directory of Open Access Journals (Sweden)

    Alessandro Aina

    2016-10-01

    knee prosthesis Cislaghi M, Penone G, Marinelli G, Rezzan G, Melegati G, Gatti R P14 The use of Kinesio Taping in the treatment of hematomas: can we distinguish fancy from the effects? Colombo Claudio, Tolosa Francesca, Andrea Moriondo, Vercelli Stefano P15 Who is able to perform explicit motor imagery after stroke? Stefano Doronzio, Matteo Paci P16 Responsiveness of the Bridge tests in Symptomatic Lumbar Spondylolisthesis Silvano Ferrari, Carla Vanti, Marco Monticone P17 The relationship between number of sessions and clinical results in lumbar symptomatic spondylolisthesis Silvano Ferrari, Carla Vanti, Marco Monticone P18 Conservative treatments for upper extremity tendinopathies in occupational medicine: narrative review Garzonio Fabiola, Zanetta Anna, Bargeri Serena, Cerone Giorgia, Sartorio Francesco P19 The time-related effect of roller-massager on extensibility of the hamstring muscles Filippo Ghirlanda, Alessandro Schneebeli, Corrado Cescon, Marco Barbero P20 Effect of two different exercise programs on pain, disability and quality of life in people with subacute and chronic nonspecific neck pain Gioia G, Faccendini S, Aina A, Tettamanti A P21 A bridge between clinical practice and research: how health professionals can study literature and learn on the job Granzotto G, Coppola L, Gava I, Frassinelli M, Gattinoni F P22 Walking capacity improves after neuromotor physiotherapy in stroke patients Lorenzo Guidotti, Marco Postiglione, Bruna Lombardi, Matteo Paci P23 Intra and inter-session reliability of the angle between pain onset and submaximal pain during upper limb neurodynamics test 1: a study in healty individuals Diego Leoni, Davide Storer, Roberto Gatti, Michele Egloff, Marco Barbero P24 Effects of an AO-MI training on balance task in patients affected by multiple sclerosis Magno Tiziano, Tettamanti Andrea P25 Outcomes of treatment with neuromuscular stimulator for chronic anterior knee pain: a clinical case Daniele Maremmani, Sebastiano Cencini, Giuseppe

  14. EPICTETO: TESTEMUNHOS E FRAGMENTOS

    Directory of Open Access Journals (Sweden)

    Alfredo Julien

    2008-01-01

    Full Text Available Traducao bilingue dos fragmentos de Epicteto, com artigos de Alfredo Julien (doutor em historia pela USP, Fabio Duarte Joly (doutor em historia pela USP e Aldo Dinucci (doutor em filosofia pela PUC/RJ. Texto publicado em 2008 pela Editora da Universidade Federal de Sergipe. Os fragmentos sao traduzidos por Dinucci e Julien, e anotados por Dinucci.

  15. 75 FR 53851 - Airworthiness Directives; Bombardier, Inc. Model CL-600-2C10 (Regional Jet Series 700, 701 & 702...

    Science.gov (United States)

    2010-09-02

    ... discovered that when the outflow valve (OFV) manual mode connector is not connected, the manual mode motor... control] backup/safety functions, including OFV manual control, altitude limitation, emergency...., Washington, DC. FOR FURTHER INFORMATION CONTACT: Fabio Buttitta, Aerospace Engineer, Airframe and...

  16. Proceedings of the Third International Symposium on Ground Freezing Held at Hanover, New Hampshire on 22-24 June 1982.

    Science.gov (United States)

    1982-01-01

    but at a soil strong condensation-cementation moisture content equal to the ma- structures are formed. Here, for ximum molecular moisture capaci...RESULTS ON THE FREEZING OF SATURATED SANDS Fabio Gori Fisica Tecnica , Fac. Ingegneria. Via S. Marta 3, Firenze, Italy. Maura Ughi Ist. Matematico, U

  17. Experiments designed to shed light on the mysterious phenomenon of neutrino oscillation

    CERN Multimedia

    2006-01-01

    "The delivery of the neutrino beam (CNGS) from Cern and the beginning of a new generation of experiments were officially celebrated today at Infn (Italian National Institute for Nuclear Physics) national laboratories of Gran Sasso with the participation of Fabio Mussi, Minster of Universities and Research." (2 pages)

  18. Como creció esta vaina

    Directory of Open Access Journals (Sweden)

    Gloria Beatriz Salazar

    1993-09-01

    Full Text Available Ciudad y territorio: El proceso de poblamiento en Colombia. Fabio Zambrano y Olivier Bernard (Presentación de Alberto Saldarriaga Roa Academia de Historia de Bogotá, Instituto Francés de Estudios Andinos, Tercer Mundo Editores, Santafé de Bogotá, 1993, 297 págs.

  19. Download the whole Issue (9Mb

    Directory of Open Access Journals (Sweden)

    Redazione Reti Medievali (a cura di

    2010-12-01

    Full Text Available Peer reviewed by Renato Bordone, Filippo Burgarella, Sandro Carocci, Alexandra Chavarria Arnau, Simone Collavini, Salvatore Cosentino, Cristina La Rocca, Lech Leciejewicz, Jean-Claude Maire Vigueur, Marc Mayer, Eduardo Manzano Moreno, Fabio Saggioro, Chris Wickham, Enrico Zanini, Luca Zavagno.

  20. Análise proteômica das estirpes selvagem, ntrC- e nifA- de Herbaspirillum seropedicae /

    OpenAIRE

    Chaves, Daniela Fojo Seixas

    2004-01-01

    Orientador : Fabio de Oliveira Pedrosa Dissertaçăo (mestrado) - Universidade Federal do Paraná, Setor de Ciencias Biológicas, Programa de Pós-Graduaçao em Bioquímica. Defesa: Curitiba, 2004 Inclui bibliografia

  1. Peidetud köögid / Ketlin Priilinn

    Index Scriptorium Estoniae

    Priilinn, Ketlin, 1982-

    2006-01-01

    Kabinetti suletud köök Tivali (Dante Bonuccelli), köök K11 (Norbert Wangen), köögimööbel Modus (Paola Nava, Fabio Casiraghi), köök Pantos Chef (Antonia Astor), köök Single (AlbertoColonello)

  2. Introduction to multivariate analysis linear and nonlinear modeling

    CERN Document Server

    Konishi, Sadanori

    2014-01-01

    ""The presentation is always clear and several examples and figures facilitate an easy understanding of all the techniques. The book can be used as a textbook in advanced undergraduate courses in multivariate analysis, and can represent a valuable reference manual for biologists and engineers working with multivariate datasets.""-Fabio Rapallo, Zentralblatt MATH 1296

  3. Bagatellid : maailm / Nele-Eva Steinfeld, Harry Liivrand, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2010-01-01

    Uudiseid maailmast: Helilooja Jennifer Higdon pälvis Pulitzeri preemia. Fabio Luisist sai Metropolitan Opera esimene külalisdirigent. "Operalia" võitjad Sonya Yoncheva ja Stefan Pop. Lahkus metsosopran Giulietta Simionato. Kaija Saariaho uus ooper "Emilie" Amsterdamis. Hollandi maineka jazziauhinna noppis Anton Goudsmit. Herbie Hancock tähisats juubelit. Jagati reggae- ja maailmamuusika auhindu. Ilmus Stevie Wonderi biograafia

  4. Genetically Engineered Autologous Cells for Antiangiogenic Therapy of Breast Cancer

    Science.gov (United States)

    2004-07-01

    Separating viral genes on two different plasmids. J. Virol. 62: 1120-1124. 33. Hasler , A.H., and Giger, U. (2000). Polycythemia. In Textbook of...Kenzaburo Toni Reconstitution Carol H, Miao, Qili Zhu, Ling Zhou, Stephanie Humblet- 911 Baron, Datien Lin, Donald B. Kohn, Fabio Candotti, MHC Class

  5. Suur fondijuhtide ülevaade

    Index Scriptorium Estoniae

    2006-01-01

    Küsimustele vastavad Toomas Reisenbuk, Valdur Jaht, Mehis Raud, Siim Valner, Vahur Madisson, Meelis Angerma, Alo Kullamaa, Endriko Võrklaev, Arne Randmaa, Andrei Zaborski, Robert Kitt, Fabio Filipozzi, Martin Hendre, Piotr Chorzewski, Artjom Saia, Aari Stalde ja Märten Kress

  6. A vueltas con Samuel Beckett

    Directory of Open Access Journals (Sweden)

    José María Fernández Cardo

    2010-01-01

    Full Text Available A propósito de la obra de Lourdes Carriedo, Mª Luisa Guerrero, Carmen Méndez y Fabio Vericat(eds.: A vueltas con Beckett. Aproximaciones críticas en su centenario (Madrid, Ediciones de La Discreta,col. «Bártulos», 2009, 362 páginas, ISBN: 978-84-96322-29-5.

  7. Bagatellid : maailm / Nele-Eva Steinfeld, Harry Liivrand, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2010-01-01

    Uudiseid maailmast: Helilooja Jennifer Higdon pälvis Pulitzeri preemia. Fabio Luisist sai Metropolitan Opera esimene külalisdirigent. "Operalia" võitjad Sonya Yoncheva ja Stefan Pop. Lahkus metsosopran Giulietta Simionato. Kaija Saariaho uus ooper "Emilie" Amsterdamis. Hollandi maineka jazziauhinna noppis Anton Goudsmit. Herbie Hancock tähisats juubelit. Jagati reggae- ja maailmamuusika auhindu. Ilmus Stevie Wonderi biograafia

  8. Suur fondijuhtide ülevaade

    Index Scriptorium Estoniae

    2006-01-01

    Küsimustele vastavad Toomas Reisenbuk, Valdur Jaht, Mehis Raud, Siim Valner, Vahur Madisson, Meelis Angerma, Alo Kullamaa, Endriko Võrklaev, Arne Randmaa, Andrei Zaborski, Robert Kitt, Fabio Filipozzi, Martin Hendre, Piotr Chorzewski, Artjom Saia, Aari Stalde ja Märten Kress

  9. Estimación de la radiación solar global incidente en superficies inclinadas (ING

    Directory of Open Access Journals (Sweden)

    Jaime Wright

    2016-03-01

    The curves in this paper will be useful for large scale installations of solar collectors or photovoltaic panels in terrain with variable slopes in the geographic regions of the Central Valley (represented by Fabio Baudrit, North Pacific (represented by Santa Rosa, South Pacific (represented by Palmar Sur and the Atlantic (represented by Limón.

  10. Preparation of tools for lithographically controlled wetting and soft lithography

    OpenAIRE

    2015-01-01

    Authors: Massmiliano Cavallini, Denis Gentili, Pierpaolo Greco, Francesco Valle & Fabio Biscarini ### Abstract This protocol provides the instructions for designing and fabricating stamping tools with features ranging from nanometer to micrometer scale, including the fabrication using commercial tools such as compact disks or digital video disks. In particular the reported procedures are oriented towards the tools fabrication for lithographically controlled wetting and soft lithog...

  11. Decentralized Riemannian Particle Filtering with Applications to Multi-Agent Localization

    Science.gov (United States)

    2012-06-14

    unscented transform [143], and the re- duced UT [142]. Another alternative is based on Gauss -Hermite quadrature rule and was presented in [125...Information Fusion. 1999. 31. Ben Upcroft, Tobias Kaupp Matthew Ridley Lee-Ling Ong Suresh Kumar Tim Bai- ley Fabio Ramos Salah Sukkarieh, Bertrand

  12. Using DInSAR as a tool to detect unstable terrain areas in an Andes region in Ecuador (South America)

    Science.gov (United States)

    Mayorga Torres, Tannia

    2014-05-01

    deeper into vegetation cover than C band (Raucoules et al., 2007). The study processed ERS with descending orbit and ALOS with ascending orbit, due to the availability of data. Ferretti et al. (2007) said that ERS looks to the right and a slope mainly oriented to the west could have foreshortening effect in ascending orbit. Wei & Sandwell (2010) mention that ALOS in ascending orbit identifies vertical mass movements along fault systems; however, descending data has better geometry to measure mass movements. The study has fewer scenes in descending orbit. For further work, ALOS 2 will let to have more data in descending orbit. 4. CENTRAL CONCLUSIONS For mass movement having high-resolution radar is the best option; however, this data is not useful on all due to cover vegetation. Characterizing mass movements in Ecuador in necessary to put monitoring systems to avoid economic and human lost. Processing ERS and ALOS data was very useful because penetration band results were clearly identified in coherence masks. The result of Stacking DInSAR did not show clearly fringes, indeed the amount of interferograms were no enough for this technique. Researching other DInSAR techniques is necessary due to the singular characteristics of Ecuador. 5. REFERENCES Ferretti Alessandro, Monti-Guarnieri Andrea, Prati Claudio, Rocca Fabio, Massonnet Didier (2007). InSAR Principles: Guidelines for SAR Interferometry Processing and Interpretation (TM-19, Febrero 2007). K. Fletcher, Agencia Espacial Europea Publicaciones. ESTEC. Postbus 2009. 2200 AG Noordwijk. The Netherlands. Raucoules Daniel, Colesanti Carlo, Carnec Claudie (2007). "Use of SAR interferometry for detecting and assessing ground subsidence." C. R. Geoscience 339(289-302): 14. Sandwell David T., Price Evelyn J. (1998). "Phase gradient approach to stacking interferograms." Journal of Geophysical Research 103(N. B12): 30, 183-30, 204. Wei Meng, Sandwell David T (2010). "Decorrelation of L-Band and C-Band Interferometry Over

  13. Physics in one dimension

    Science.gov (United States)

    van Houselt, A.; Schäfer, J.; Zandvliet, H. J. W.; Claessen, R.

    2013-01-01

    Pashkin, C A Kuntscher, S G Ebbinghaus, M Hanfland, F Lissner, Th Schleid and M Dressel Photoemission spectroscopy and the unusually robust one-dimensional physics of lithium purple bronzeL Dudy, J D Denlinger, J W Allen, F Wang, J He, D Hitchcock, A Sekiyama and S Suga Luttinger liquid behaviour of Li0.9Mo6O17 studied by scanning tunnelling microscopyT Podlich, M Klinke, B Nansseu, M Waelsch, R Bienert, J He, R Jin, D Mandrus and R Matzdorf Mn-silicide nanostructures aligned on massively parallel silicon nano-ribbonsPaola De Padova, Carlo Ottaviani, Fabio Ronci, Stefano Colonna, Bruno Olivieri, Claudio Quaresima, Antonio Cricenti, Maria E Dávila, Franz Hennies, Annette Pietzsch, Nina Shariati and Guy Le Lay Iridium silicide nanowires on Si(001) surfacesNuri Oncel and Dylan Nicholls Structure and growth of quasi-one-dimensional YSi2 nanophases on Si(100)V Iancu, P R C Kent, S Hus, H Hu, C G Zeng and H H Weitering Metallic rare-earth silicide nanowires on silicon surfacesMario Dähne and Martina Wanke One-dimensional collective excitations in Ag atomic wires grown on Si(557)U Krieg, C Brand, C Tegenkamp and H Pfnür Interfering Bloch waves in a 1D electron systemR Heimbuch, A van Houselt, M Farmanbar, G Brocks and H J W Zandvliet Au-induced quantum chains on Ge(001)—symmetries, long-range order and the conduction pathC Blumenstein, S Meyer, S Mietke, J Schäfer, A Bostwick, E Rotenberg, R Matzdorf and R Claessen

  14. Divine Performance

    DEFF Research Database (Denmark)

    Schneider, Magnus Tessing

    2006-01-01

    Essay on the Orpheus figure as a personification of the transcendent dimension of art, and how this motive has been treated in the philosophy of Marsilio Ficino as well as in four operas: Jacopo Peri's L'Euridice (1600), Claudio Monteverdi's L'Orfeo (1607), C. W. Gluck's Orfeo ed Euridice (1762) ...

  15. Diagnosis of AIDS-Related Intestinal Parasites

    Science.gov (United States)

    1988-01-07

    Peru), Claudio F. Lanata (Instituto de Investigacion Nutricional , Lima, Peru) and Irene Perez-Schael (Instituto de Biomedicina, Caracas, Venezuela) (15...above) and Homero Martinez, M.D., Instituto National de la Nutricion , Mexico City. In this study, 53 children with at least one microscopic stool

  16. Historien er ikke slut

    DEFF Research Database (Denmark)

    Thurah, Thomas

    , Seamus Heaney, Stefan Heym, Peer Hultberg, Per Højholt, Imre Kertész, Jan Kjærstad, Ivan Klíma, Jaan Kross, Siegfried Lenz, Claudio Magris, Antonio Muñoz Molina, Cees Nooteboom, Ljudmila Petrusjevskaja, Christoph Ransmayr, Klaus Rifbjerg, Salman Rushdie, José Saramago, Peter Seeberg, Tage Skou...

  17. Cent’anni dopo: la Grande Guerra e la cultura politica britannica

    Directory of Open Access Journals (Sweden)

    Maria Chiara Pievatolo

    2014-12-01

    Full Text Available Claudio Palazzolo ha scelto di pubblicare ad accesso aperto il suo intervento al convegno L’Italia e l’Europa di fronte alla Grande Guerra, dedicato a La Grande Guerra e la cultura politica britannica. Il suo testo, depositato nell’archivio Marini, è a...

  18. R-matrix Methods with an application to 12C(alpha,gamma)16O

    OpenAIRE

    Brune, Carl R.

    2010-01-01

    Comment: 7 pages. Published in the Proceedings of the Fifth European Summer School on Experimental Nuclear Astrophysics, Santa Tecla, Sicily, Italy, 20-27 September 2009, Editors Claudio Spitaleri, Claus Rolfs, and Rosario Gianluca Pizzone, AIP Conference Proceedings number 1213 (AIP, New York, 2010), pp. 35-41

  19. Il capitale monopolistico di Baran e Sweezy e la teoria marxiana del valore

    Directory of Open Access Journals (Sweden)

    Claudio Napoleoni

    2015-03-01

    Full Text Available The text is the transcript of a lecture given on 12 May 1973 by Claudio Napoleoni, as part of a course on Economic and financial policy at the University of Turin. The lecture, edited by Riccardo Bellofiore, concerns Baran and Sweezy’s Monopoly Capital and its relation to Marx’s theory of value.

  20. Crisi e centralizzazione del capitale finanziario

    Directory of Open Access Journals (Sweden)

    Emiliano Brancaccio

    2015-03-01

    Full Text Available The text is the transcript of a lecture given on 12 May 1973 by Claudio Napoleoni, as part of a course on Economic and financial policy at the University of Turin. The lecture, edited by Riccardo Bellofiore, concerns Baran and Sweezy’s Monopoly Capital and its relation to Marx’s theory of value.

  1. Petras tunge

    DEFF Research Database (Denmark)

    Thurah, Thomas

    hovedstæder, små og store metropoler, hvor historien har sat sig tydelige spor og endnu gør det for magtfuldt og tilsyneladende tvivlløst at bevidne en ny tingenes orden. Litteraturen skrives af bl.a. Martin Amis, Hanif Kureishi, Marcel Beyer, Günter Grass, Milan Kundera, Cees Nooteboom, Aldo Busi, Claudio...

  2. Kaitstud magistritööd, 1. juuni 2012

    Index Scriptorium Estoniae

    2013-01-01

    Oma töid kaitsesid Claudio Julio Rodriguez Higuera, Davi William Ferreira Gomes, Karlina Vaivade, Mohamed Gamal Abdelmeged Elmaayergy, Sigita Tamošauskaite, Eduardo Chávez Herrera, Tyler James Bennett, Felipe Cuervo Restrepo, Julia Popova, Anastasiia Sidielnik, Thomas Mark Boyle, Mirjam Männik, Sandra Preiman, Tamara Stojanovic

  3. Acknowledgements

    NARCIS (Netherlands)

    Hendrix, H.

    In February 2009, the University of Utrecht welcomed Claudio Magris as its first writer-in-residence, in a new and ambitious programme launched in order to bring the Utrecht academic community in close contact with some of the world’s finest and most accomplished poets and writers. While at Utrecht

  4. Davanti alla legge. Letteratura e diritto

    NARCIS (Netherlands)

    Magris, Claudio

    Durante la sua permanenza in quanto scrittore ospite all’Università di Utrecht nel febbraio 2009, Claudio Magris pronunciò – in inglese – la prima ‘Romano Guarnieri Lecture in Italian Studies’, scegliendo come tema il rapporto fra letteratura e diritto. Nella sua prolusione Magris afferma che la

  5. Acknowledgements

    NARCIS (Netherlands)

    Hendrix, H.

    2009-01-01

    In February 2009, the University of Utrecht welcomed Claudio Magris as its first writer-in-residence, in a new and ambitious programme launched in order to bring the Utrecht academic community in close contact with some of the world’s finest and most accomplished poets and writers. While at Utrecht

  6. Davanti alla legge. Letteratura e diritto

    NARCIS (Netherlands)

    Magris, Claudio

    2009-01-01

    Durante la sua permanenza in quanto scrittore ospite all’Università di Utrecht nel febbraio 2009, Claudio Magris pronunciò – in inglese – la prima ‘Romano Guarnieri Lecture in Italian Studies’, scegliendo come tema il rapporto fra letteratura e diritto. Nella sua prolusione Magris afferma che la let

  7. Sisustusgiidi uudised / Mari Masso

    Index Scriptorium Estoniae

    Masso, Mari

    2007-01-01

    Uut elutoa mööblit Eesti poodides - diivan Janno Roosilt ja Andres Labilt, tugitool Patricia Urquiolalt, Zaha Hadidi disainitud laud "Aqua", Mareo Marani pöördjalaga tool "Free" ja erinevate mustritega lauad disainistuudiolt Archivolto (disainerid Claudio Dondoli ja Marco Pocci). Lk. 58 Ell-Maaja Randküla kommentaar

  8. Bagatellid : maailm / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2007-01-01

    Lahkus Luciano Pavarotti. CD-plaat tähistas 25 aasta juubelit. Claudio Abbado on muusikamaailma suuremast saginast pisut tagasi tõmbunud. Robot mängib löökpille. Ooperikardinate taga: läbipõlenud lauljad

  9. Muusikauudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2016-01-01

    Lühisõnumeid maailmast: Suri Nikolaus Harnoncourt. Grammy selleks aastaks jagatud. Claudio Abbado pärand liigub Berliini. Piotr Anderszewski võtab aja maha. Polar Music Prize Cecilia Bartolile. Lahkus USA helilooja Steven Stucky. Händeli kantaadi seni tundmatu versioon

  10. UEFA ametnik laitis staadionide seisukorda / Nils Niitra

    Index Scriptorium Estoniae

    Niitra, Nils, 1975-

    2004-01-01

    UEFA noorte- ja amatöörjalgpalli projektijuht Claudio Negroni andis Tartu ja selle lähiümbruse staadionidele ebarahuldava hinde. Tamme staadionil tehakse 16 miljonit krooni maksev remont, et seal saaks 2007.a. toimuda 19-aastaste noormeeste Euroopa jalgpalli meistrivõistluste finaalturniir

  11. Kunstnikuks pürgija vajab paari õigeaegset impulssi / Kaido Ole, Eva Unt

    Index Scriptorium Estoniae

    Ole, Kaido

    2006-01-01

    Antonia Claudio Carvalho meistriklass "Ava oma silmad/Open Your Eyes" 23.-27. I ja näitus 27. I-9. II Eesti Kunstiakadeemia galeriis. Meistriklassist vestlesid EKA maaliosakonna juhataja Kaido Ole ja maalieriala III kursuse üliõpilane Eva Unt

  12. Uudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2013-01-01

    Claudio Abbado kuulutati eluaegseks senaatoriks. Erkki-Sven Tüüri uudisteos "Peregrinus ecstaticus" Helsingis, Stockholmis renoveeritakse ooperimaja. Minnesota orkestri probleemid jätkuvad. "BBC Promsi" festivali edukas suvi. Titanicu pardal kõlanud viiul läheb näitusele ja oksjonile. Suri Ray Dolby

  13. Estudo do comportamento rotatório induzido por diferentes substancias em ratos com lesão induzida por 6-OHDA no feixe prosencefalico medial (FPM) /

    OpenAIRE

    Gregorio,Michele Lima

    2007-01-01

    Orientador : Claudio da Cunha Co-orientadora : Maria Aparecida B.F. Vidal Dissertação (mestrado) - Universidade Federal do Paraná, Setor de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia. Defesa: Curitiba, 2007 Inclui bibliografia

  14. Uudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2013-01-01

    Claudio Abbado kuulutati eluaegseks senaatoriks. Erkki-Sven Tüüri uudisteos "Peregrinus ecstaticus" Helsingis, Stockholmis renoveeritakse ooperimaja. Minnesota orkestri probleemid jätkuvad. "BBC Promsi" festivali edukas suvi. Titanicu pardal kõlanud viiul läheb näitusele ja oksjonile. Suri Ray Dolby

  15. Kunstnikuks pürgija vajab paari õigeaegset impulssi / Kaido Ole, Eva Unt

    Index Scriptorium Estoniae

    Ole, Kaido

    2006-01-01

    Antonia Claudio Carvalho meistriklass "Ava oma silmad/Open Your Eyes" 23.-27. I ja näitus 27. I-9. II Eesti Kunstiakadeemia galeriis. Meistriklassist vestlesid EKA maaliosakonna juhataja Kaido Ole ja maalieriala III kursuse üliõpilane Eva Unt

  16. Sisustusgiidi uudised / Mari Masso

    Index Scriptorium Estoniae

    Masso, Mari

    2007-01-01

    Uut elutoa mööblit Eesti poodides - diivan Janno Roosilt ja Andres Labilt, tugitool Patricia Urquiolalt, Zaha Hadidi disainitud laud "Aqua", Mareo Marani pöördjalaga tool "Free" ja erinevate mustritega lauad disainistuudiolt Archivolto (disainerid Claudio Dondoli ja Marco Pocci). Lk. 58 Ell-Maaja Randküla kommentaar

  17. UEFA ametnik laitis staadionide seisukorda / Nils Niitra

    Index Scriptorium Estoniae

    Niitra, Nils, 1975-

    2004-01-01

    UEFA noorte- ja amatöörjalgpalli projektijuht Claudio Negroni andis Tartu ja selle lähiümbruse staadionidele ebarahuldava hinde. Tamme staadionil tehakse 16 miljonit krooni maksev remont, et seal saaks 2007.a. toimuda 19-aastaste noormeeste Euroopa jalgpalli meistrivõistluste finaalturniir

  18. Bagatellid : maailm / Mirjam Tally

    Index Scriptorium Estoniae

    Tally, Mirjam, 1976-

    2007-01-01

    Lahkus Luciano Pavarotti. CD-plaat tähistas 25 aasta juubelit. Claudio Abbado on muusikamaailma suuremast saginast pisut tagasi tõmbunud. Robot mängib löökpille. Ooperikardinate taga: läbipõlenud lauljad

  19. Muusikauudiseid maailmast / Nele-Eva Steinfeld

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2016-01-01

    Lühisõnumeid maailmast: Suri Nikolaus Harnoncourt. Grammy selleks aastaks jagatud. Claudio Abbado pärand liigub Berliini. Piotr Anderszewski võtab aja maha. Polar Music Prize Cecilia Bartolile. Lahkus USA helilooja Steven Stucky. Händeli kantaadi seni tundmatu versioon

  20. Kaitstud magistritööd, 1. juuni 2012

    Index Scriptorium Estoniae

    2013-01-01

    Oma töid kaitsesid Claudio Julio Rodriguez Higuera, Davi William Ferreira Gomes, Karlina Vaivade, Mohamed Gamal Abdelmeged Elmaayergy, Sigita Tamošauskaite, Eduardo Chávez Herrera, Tyler James Bennett, Felipe Cuervo Restrepo, Julia Popova, Anastasiia Sidielnik, Thomas Mark Boyle, Mirjam Männik, Sandra Preiman, Tamara Stojanovic

  1. From light to knowledge

    CERN Multimedia

    Globe Info

    2011-01-01

    An evening in two parts with Fabio Barblan. 1/ Light in daily life and what light means for an astronomer (exhibition). 2/ Light in all its states or how to extract information from the heavenly bodies: exploration using telescopes, space probes, spectrometry and imagery. Measuring and modelling using light (physical parameters, distances, etc.) Fabio Barblan is "an external scientific collaborator" and member of the photometry, stellar variability and GAIA group at the Observatoire de Genève. Observatoire de Genève Friday 14 October from 8:30 p.m. to 10:00 p.m. » Suitable for all – Admission free - Lecture in French For further information: +33 (0)4 50 41 96 80

  2. Chemical Stockpile Disposal Program Final Programmatic Environmental Impact Statement Volume 3: Appendices A-S

    Science.gov (United States)

    1988-01-01

    exposures produce behavioral and cardiovascular symptoms in man. Methylene chloride tested positive for carcinogenicity in rats (Fund. Appl. Toxicol... Cardiovascular Effects of Anticholinesterase Medications," Am. J. Med. Sci. 293(l), 18-23. Auerbach, C. H. 1950. "Differences Between Effects of Chemical...1, 1371-74. B-185 Ghiringhelli, L., and Di Fabio, A. 1957. ." Patologia da acido acetico: osservazioni negli animali da esperimento e nell’uomo

  3. I/O-Intensive Embedded Systems: The Infopipe Approach

    Science.gov (United States)

    2004-07-01

    T. Leen, Y. Zhang, A. Chawla, D. Maier, W-Chi Feng, Wu-Chang Feng, J. Walpole, C. Silva and J. Freire , in Proceedings of the International Society...Statistics, and Computing, University of Sao Paulo , “Continual Queries: Intelligent Access to Fresh Information”. Host: Prof. Joao Ferreira. 52...11/28/03, University of Sao Paulo , Sao Paulo , Brazil, “Infosphere: A Midterm Update on Infopipes”. Host: Prof. Fabio Kon and Joao Eduardo Ferreira

  4. MOVIMIENTOS SINFONICOS DE UN ARQUITECTO

    Directory of Open Access Journals (Sweden)

    Guillermo E. Felix Tejera

    1996-01-01

    Full Text Available Compositor, pintor, escultor, administrador, pedagogo, director del Conservatorio e investigador, el Maestro Fabio González Zuleta fue construyendo su vida a golpes de sensibilidad, imaginación y entrega al servicio de la música, de los músicos y de todos los que creen en el desarrollo integral del ser humano a través del arte.

  5. Mobile point-of-care monitors and diagnostic device design

    CERN Document Server

    Karlen, Walter

    2014-01-01

    PrefaceEditorsContributorsSensors and SystemsInterfacing Diagnostics with Consumer ElectronicsPakorn Preechaburana, Anke Suska, and Daniel FilippiniLab on a CellphoneAhmet F. Coskun, Hongying Zhu, Onur Mudanyali, and Aydogan OzcanThe Phone OximeterChristian Leth PetersenCurrent Technology and Advances in Transepidermal Water Loss SensorsPietro Salvo, Bernardo Melai, Nicola Calisi, and Fabio Di FrancescoPortable High-Frequency Ultrasound Imaging System Design and Hardware Considerations

  6. Concursos

    Directory of Open Access Journals (Sweden)

    Boletín Cultural y Bibliográfico Banco de la República

    2000-05-01

    Full Text Available Se presenta la convocatoria, información y bases de los siguientes concursos:  premio Poesía Orippo, Premio Alfred Hitchcock de cuento breve, Premio Charles Baudelaire, I Concurso de cuentos taurinos "El Albero", IV Concurso de relatos "El melocotón mecánico", II Premio Las Luces de biografía, Premio Biblioteca Breve Seix Barral, XVII Premio internacional de cuentos "Max Aub", IX Certamen premios literarios Marco Fabio Quintiliano.

  7. An Evolutionary Algorithm to Generate Ellipsoid Detectors for Negative Selection

    Science.gov (United States)

    2005-03-21

    positive integers to real numbers. Java source code that computes the Γ function has been produced by several groups, including the PAL project [87]. Ωn...Information Assurance Technology Analysis Center, 2001. 23. Dasgupta, Dipankar (editor). Artificial Immune Systems and Their Applications. Springer-Verlag...Berlin, 1999. 24. Dasgupta, Dipankar and Fabio Gonzalez. “An Immunity-Based Technique to Charac- terize Intrusions in Computer Networks”. IEEE

  8. Movimientos sinfónicos de un arquitecto

    Directory of Open Access Journals (Sweden)

    Guillermo E. Felix Tejera

    1996-04-01

    Full Text Available Compositor, pintor, escultor, administrador, pedagogo, director del Conservatorio e investigador, el Maestro Fabio González Zuleta fue construyendo su vida a golpes de sensibilidad, imaginación y entrega al servicio de la música, de los músicos y de todos los que creen en el desarrollo integral del ser humano a través del arte.

  9. Matrix metalloproteinases in impaired wound healing

    OpenAIRE

    auf dem Keller, Ulrich; Sabino,Fabio

    2015-01-01

    Fabio Sabino, Ulrich auf dem Keller Institute of Molecular Health Sciences, Eidgenössische Technische Hochschule (ETH) Zürich, Zürich, Switzerland Abstract: Cutaneous wound healing is a complex tissue response that requires a coordinated interplay of multiple cells in orchestrated biological processes to finally re-establish the skin's barrier function upon injury. Proteolytic enzymes and in particular matrix metalloproteinases (MMPs) contribute to all phas...

  10. Chondroma of the hand with osteoid formation: first case report

    Directory of Open Access Journals (Sweden)

    Arena V

    2011-07-01

    Full Text Available Vincenzo Arena, Ilaria Pennacchia, Fabio Maria Vecchio, Arnaldo CarboneInstitute of Pathology, Catholic University of Sacred Heart, Rome, ItalyAbstract: Chondroma is the most common neoplasia of the hand. Histologically, it consists of lobules of normal-appearing hyaline cartilage showing a lobular arrangement. To the best of our knowledge, this is the first reported case of chondroma of the hand in which, interestingly, osteoid production was observed.Keywords: chondroma, hand, osteoid

  11. Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

    OpenAIRE

    De Sanctis R; Marrari A; Marchetti S; Mussi C; Balzarini L.; Lutman FR; Daolio P; Bastoni S; Bertuzzi AF; Quagliuolo V; Santoro A.

    2015-01-01

    Rita De Sanctis,1 Andrea Marrari,1 Silvia Marchetti,1 Chiara Mussi,2 Luca Balzarini,3 Fabio Romano Lutman,3 Primo Daolio,4 Stefano Bastoni,4 Alexia Francesca Bertuzzi,1,5 Vittorio Quagliuolo,2 Armando Santoro1 1Department of Medical Oncology and Haematology, 2Department of Surgical Oncology, 3Department of Radiology, Humanitas Cancer Center, IRCCS, Rozzano, 4Department of Surgical Oncology, Orthopaedic Institute “G. Pini”, Milan, Italy; 5Department of Medical Onc...

  12. Effect of prophylactic timolol 0.1% gel on intraocular pressure after an intravitreal injection of ranibizumab: a randomized study

    OpenAIRE

    Pece A; Allegrini D; Montesano G; Dimastrogiovanni AF

    2016-01-01

    Alfredo Pece,1 Davide Allegrini,1 Giovanni Montesano,2 Andrea Fabio Dimastrogiovanni1 1Eye Clinic, Melegnano Hospital, Vizzolo Predabissi, 2Eye Clinic, San Paolo Hospital, Università di Milano, Milano, Italy Purpose: The purpose of this study is to make a prospective evaluation of the effect of timolol 0.1% eye gel on short-term intraocular pressure (IOP) after an intravitreal injection (IVI) of ranibizumab. Participants and methods: One hundred and fifty eyes of 150 IVI-na&i...

  13. Potential drug–drug interactions in Alzheimer patients with behavioral symptoms

    OpenAIRE

    2015-01-01

    Giuseppe Pasqualetti, Sara Tognini, Valeria Calsolaro, Antonio Polini, Fabio Monzani Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy Abstract: The use of multi drug regimens among the elderly population has increased tremendously over the last decade although the benefits of medications are always accompanied by potential harm, even when prescribed at recommended doses. The elderly populations are particularly at an increased risk of adverse ...

  14. Postfeminist (Dis)Entanglements: Transgression and Conformism in Contemporary Italian Teen Movies

    OpenAIRE

    Bonifazio, Paola

    2016-01-01

    According to film historian Giampiero Brunetta, the success of Luca Lucini’s Tre metri sopra il cielo (Three Steps Over Heaven, 2004) and Fabio Brizzi’s Notte prima degli esami (Night Before the Exams, 2006) is emblematic of the current “crisis” of Italian cinema. The premise of Brunetta’s negative comments are primarily aesthetics (bad script, bad direction), while other reviewers have blamed the same films for unrealistic portrayals of Italian teenagers, and expressed their concerns about t...

  15. Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2011-01-01

    Muusikasõnumeid maailmast: Hollandi kultuurielu kriis. Toetus Londoni Filharmooniaorkestrist vallandatud muusikutele. Veebilehest: arkivmusic.eu. Lahkus Kurt Sanderling. Hiinas keelustati ajaloolise sisuga ooper. Dirigent Mark Gorenstein vallandati ametist. Beethoveni kvarteti taastatud osa. Värskeid plaadilepinguid. Bostoni sümfooniaorkester otsib muusikalist juhti. Fabio Luisil probleem kodumaiste ooperimajadega. Itaalia jazzi pevad New Yorgis. Värskeid plaate jazzimaailmast. Tony Bennett purustas rekordi. DownBeati aasta jazzmuusik on Jason Moran

  16. Bagatellid : maailm / Nele-Eva Steinfeld, Ivo Heinloo

    Index Scriptorium Estoniae

    Steinfeld, Nele-Eva

    2011-01-01

    Muusikasõnumeid maailmast: Hollandi kultuurielu kriis. Toetus Londoni Filharmooniaorkestrist vallandatud muusikutele. Veebilehest: arkivmusic.eu. Lahkus Kurt Sanderling. Hiinas keelustati ajaloolise sisuga ooper. Dirigent Mark Gorenstein vallandati ametist. Beethoveni kvarteti taastatud osa. Värskeid plaadilepinguid. Bostoni sümfooniaorkester otsib muusikalist juhti. Fabio Luisil probleem kodumaiste ooperimajadega. Itaalia jazzi pevad New Yorgis. Värskeid plaate jazzimaailmast. Tony Bennett purustas rekordi. DownBeati aasta jazzmuusik on Jason Moran

  17. Central serous chorioretinopathy: a pathogenetic model

    OpenAIRE

    Caccavale, Antonio

    2011-01-01

    Antonio Caccavale1, Filippo Romanazzi1, Manuela Imparato1, Angelo Negri2, Anna Morano3, Fabio Ferentini21Department of Ophthalmology, Neuropthalmology and Ocular Immunology Service, 2Department of Ophthalmology, Hospital “C. Cantù”, Abbiategrasso, Milan, Italy; 3University Eye Clinic, Foundation IRCCS San Matteo Hospital, Pavia, ItalyAbstract: Despite numerous studies describing predominantly its demography and clinical course, many aspects of central serous cho...

  18. The External Mind

    DEFF Research Database (Denmark)

    The External Mind: an Introduction by Riccardo Fusaroli, Claudio Paolucci pp. 3-31 The sign of the Hand: Symbolic Practices and the Extended Mind by Massimiliano Cappuccio, Michael Wheeler pp. 33-55 The Overextended Mind by Shaun Gallagher pp. 57-68 The "External Mind": Semiotics, Pragmatism......, Extended Mind and Distributed Cognition by Claudio Paolucci pp. 69-96 The Social Horizon of Embodied Language and Material Symbols by Riccardo Fusaroli pp. 97-123 Semiotics and Theories of Situated/Distributed Action and Cognition: a Dialogue and Many Intersections by Tommaso Granelli pp. 125-167 Building...... Action in Public Environments with Diverse Semiotic Resources by Charles Goodwin pp. 169-182 How Marking in Dance Constitutes Thinking with the Body by David Kirsh pp. 183-214 Ambiguous Coordination: Collaboration in Informal Science Education Research by Ivan Rosero, Robert Lecusay, Michael Cole pp. 215-240...

  19. Botánica médica de los indígenas Cuna de Arquía, Chocó

    Directory of Open Access Journals (Sweden)

    Giraldo Tafur Clara

    1995-11-01

    Full Text Available A medical-botanical study in the indigenous Cuna community of Arquia (Choco with the collaboration of the Inatuledi (botanical doctor Claudio Izquierdo is presented. Different aspects about health, illness and the healing process are discussed. 146 plants are relerenced including indian language and translation, a brief description of uses and applications and the taxonomical name of 53 plants.Se presenta un estudio de botánica médica realizado en la comunidad indígena Cuna de Arquía, Chocó, con la colaboración del lnatuledi (médico-botánico Claudio Izquierdo. Se discuten diferentes aspectos sobre salud y enfermedad y la terapéutica curativa. Se referencian 146 plantas con el uso, nombre en lengua y español, parte a usar y la preparación, de las cuales 53 se identificaron taxonómicamente.

  20. 资讯快递

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>Bellefontaine维美源素入驻北京新光天地7月18日,源自瑞士的护肤品Bellefontaine维美源素在北京新光天地盛大开幕,瑞士驻华大使参赞Claudio Mazzucchelli,驻中国瑞士旅游局局长Simon Bosshart,Bellefontaine瑞士总经理Mr.Peter Yip,新光天地总经理

  1. Romance e realidade na ficção brasileira contemporânea

    Directory of Open Access Journals (Sweden)

    Juliana Santini

    2012-01-01

    Full Text Available This work is a reflection on the representation of real in the novel Inferno provisório, by Luiz Ruffato, considering proposals by Claudio Magris on modern form of novel and its possible transformations in last decades. The aim is questioning the way by which aesthetic project of this novel embodies a deep point of view of real, creating an ethic and critical principle of analysis on contemporary society.

  2. Stemmer i italiensk litteratur

    DEFF Research Database (Denmark)

    omdrejningspunkt kommer danske og udenlandske forskere vidt omkring i den italienske litteratur: stemmen i ordbøgerne, stemmen hos Petrarca og i humanisternes breve, stemmens apostrofer igennem tiden, italienske stemmer hos Montaigne og humor hos Pirandello, Pirandellos stemme hos Svend Åge Madsen og Conrads...... stemme hos Calvino, litterære telefonstemmer, ny italiensk krimi, kvindestemmer før og nu, intertekstualitet hos Claudio Magris, og Magris' eget bidrag om europæiske identiteter....

  3. Highlights and Conclusions of the Chalonge 13th Paris Cosmology Colloquium

    OpenAIRE

    2010-01-01

    The 13th Chalonge Paris Cosmology Colloquium was held at the historic Perrault building of Observatoire de Paris on 23-25 July 2009. The Colloquium was held in the spirit of the Chalonge School, putting together real cosmological and astrophysical data and hard theory predictive approach in the framework of the Standard Model of the Universe. Peter Biermann, James Bullock, Claudio Destri, Hector de Vega, Massimo Giovannini, Sasha Kashlinsky, Eiichiro Komatsu, Anthony Lasenby and Norma G. Sanc...

  4. IEEE Particle Accelerator Conference on Accelerator Science and Technology Held in San Francisco, California on 6-9 May 1991. Volume 5

    Science.gov (United States)

    1991-05-01

    W. Jones, and M. J. Jakobson ...... 893 User control of the proton beam injection trajectories into the AGS booster - T. D’Ottavio, A. Kponou, A...Baird, Heinz-Dieter Nuhn , Roman Tai’chyn, Herman lWinick, Alan S. Fisher, Juan C. Gallardo, and Claudio Pellegrini...LIVERMORE CA 945W50 9700 S CASS AVENUE USA ARGONNE IL 60439 USA ROMAN J. NAWROCKY BROOKHAVEN NATL LAB WILLIAM E. JR. NEXSEN BLDG. 725B LLNL VALERIJ

  5. IEEE Particle Accelerator Conference on Accelerator Science and Technology Held in San Francisco, California on 6-9 May 1991. Volume 2

    Science.gov (United States)

    1991-05-01

    A. Browman, K. W. Jones, and M. J. Jakobson ....... 893 User control of the proton beam injection trajectories into the AGS booster - T. D’Ottavio, A... Roman Tatchyn, Herman IWinick, Alan S. Fisher, Juan C. Gallardo, and Claudio Pellegrini ....................................................... 2748...National Laboratory Los Alamos, NM 87545 M. J. Jakobson University of Montana Missoula, MT 59812 Abstract The results of the upgrade to the 750-keV H

  6. A simplified stock-flow consistent post-Keynesian growth model

    OpenAIRE

    dos Santos, Claudio H.; Zezza, Gennaro

    2005-01-01

    A Simplified Stock-Flow Consistent Post-Keynesian Growth Model Claudio H. Dos Santos* and Gennaro Zezza** Abstract: Despite being arguably the most rigorous form of structuralist/post-Keynesian macroeconomics, stock-flow consistent models are quite often complex and difficult to deal with. This paper presents a model that, despite retaining the methodological advantages of the stock-flow consistent method, is intuitive enough to be taught at an undergraduate level. Moreover, the model can eas...

  7. Research Laboratory of Electronics Progress Report Number 134

    Science.gov (United States)

    1991-12-31

    collaboration with the Dutch group headed by between two subband levels, and the other is the Profesor Horst Rogalla, which is the leading confinement of...m - ... ... ....... .. ...... . Profesor SYIVAI T. Cayer 132 ftLE Progrees Report Number 134 Chapter 3. Chemical Reaction Dynamics at Surfaces Chapter...Herbelot Janet L. Pan Claudio L. Cesar Lori K. Herold Gregory E. Penn Hwa-Ping Chang Bruce N. Ingle Brian M. Perreault Michael S. Chapman Steven H. Isabella

  8. Gravitational Lens: Deep Space Probe Design

    Science.gov (United States)

    2012-03-01

    List of Abbreviations Abbreviation Page FSM Focal Space Mission . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1 CMB Cosmic Microwave...concert with the sun’s gravitational lens to image nearby solar systems and/or other pertinent astronomical objects, e.g. the Cosmic Microwave Background...CMB) radiation. 1.2 Thesis Objective In Deep Space Flight and Communications Claudio Maccone uses the mass, radius , mean density, and Schwarzschild

  9. The role of health technology assessment bodies in shaping drug development

    OpenAIRE

    Ciani O; Jommi C

    2014-01-01

    Oriana Ciani,1,3 Claudio Jommi1,2 1Centre for Research on Health and Social Care Management (CERGAS), Bocconi University, Milan, Italy; 2Department of Pharmaceutical Sciences, Università del Piemonte Orientale, Novara, Italy; 3University of Exeter Medical School, Exeter, UK Abstract: The use of health technology assessment (HTA) to inform policy-making is established in most developed countries. Compared to licensing agencies, HTA agencies have different interests and, t...

  10. Visualization of High-Order Finite Element Methods

    Science.gov (United States)

    2013-03-27

    Peters , Valerio Pascucci, Robert M. Kirby and Claudio T. Silva, "Topology Verification for Isosurface Extraction", IEEE Transactions on Visualization...Visualization of High-Order Methods Professor Robert M. Kirby , Mr. Robert Haimes University of Utah Office of Sponsored Programs University of Utah Salt Lake...ORGANIZATION REPORT NUMBER 19a. NAME OF RESPONSIBLE PERSON 19b. TELEPHONE NUMBER Robert Kirby 801-585-3421 3. DATES COVERED (From - To) 26-Sep-2008

  11. Cláudio Santoro , Doutor Honoris Causa da Universidade de Brasília

    OpenAIRE

    Tacuchian,Ricardo

    2007-01-01

    No contexto do XVI Congresso da ANPPOM realizado em 2006 sob os auspícios do Programa de Pós-graduação Música em Contexto, Ricardo Tacuchian, enquanto membro da Academia Brasileira de Música e relator da atribuição de Doutor Honoris Causa post-mortem, relata as contribuições de Claudio Santoro no cenário da criação musical no Brasil.

  12. Conformity cannot be identified based on population-level signatures

    OpenAIRE

    Alberto Acerbi; van Leeuwen, Edwin J. C.; Haun, Daniel B. M.; Claudio Tennie

    2016-01-01

    The Netherlands Organisation for Scientific Research (NWO VIDI-grant 016.144312) supports the research of Alberto Acerbi. Claudio Tennie would like to thank the Economic and Social Research Council for financial support (ES/K008625/1). Conformist transmission, defined as a disproportionate likelihood to copy the majority, is considered a potent mechanism underlying the emergence and stabilization of cultural diversity. However, ambiguity within and across disciplines remains as to how to i...

  13. Profile of evolocumab and its potential in the treatment of hyperlipidemia

    OpenAIRE

    Cicero AF; Colletti A; Borghi C

    2015-01-01

    Arrigo FG Cicero, Alessandro Colletti, Claudio Borghi Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy Abstract: Despite the proven efficacy of statins, they often fail to achieve low-density lipoprotein (LDL) cholesterol goals, especially in high-risk patients. Moreover, a large number of subjects cannot tolerate statins or full doses of these drugs, in particular patients with familial hypercholesterolemia. Thus, there is a need for additional effective LDL ...

  14. Graafikatriennaali peapreemia läks Lätti / Kadri Karro

    Index Scriptorium Estoniae

    Karro, Kadri

    2011-01-01

    Kumu Kunstimuuseumis avatud 15. Tallinna Graafikatriennaali "Armastuse, mitte raha pärast" Grand Prix saanud Edmunds Jansonsi (Läti) animeeritud dokumentaalfilmist "Väikese linnukese päevik" (2007). Kolm võrdset preemiat pälvinud Antonio Claudio Carvalho (Brasiilia), õde Mary Corita (Corita Kent, 1918-1986, USA) ja Alina Rudnitskaja (Venemaa) töödest. Eripreemiate saajad. Oliver Laas sai ERKF Olev Soansi mälestusfondi stipendiumi

  15. punktum. März 2010

    OpenAIRE

    2010-01-01

    Bänziger, Hans Ulrich: 2010; Dr. Turmes, Luc: Bindung und Empathie. Von wechselseitigem Aufnehmen und spiegelndem Zurückgeben; Dr. Brisch, Karl Heinz: Bindungstheorie. Die Eltern-Kind-Symbiose; Prof. Dr. Gruen, Arno: Evolution. Liebe als entscheidender Entwicklungsfaktor; Dr. Waiblinger, Eva: Altruismus bei Tieren. Das Mitgefühl der Bonobos; Garstick, Egon: Elternschaftstherapie. Psychoanalytisch orientierte Psychotherapie im öffentlichen Bereich; Moro, Claudio: Selektiver M...

  16. Maude Object-Oriented Action Tool

    OpenAIRE

    Maidl, André Murbach; Carvilhe, Cláudio,; Musicante, Martin A.

    2013-01-01

    MAIDL, André Murbach; CARVILHE, Claudio; MUSICANTE, Martin A. Maude Object-Oriented Action Tool. Electronic Notes in Theoretical Computer Science. [S.l:s.n], 2008. Object-Oriented Action Semantics (OOAS) incorporates object-oriented concepts to the Action Semantics formalism. Its main goal is to obtain more readable and reusable semantics specifications. Moreover, it supports syntax-independent specifications, due to the way classes are written. Maude Object-Oriented Action Tool (MOOAT)...

  17. Graafikatriennaali peapreemia läks Lätti / Kadri Karro

    Index Scriptorium Estoniae

    Karro, Kadri

    2011-01-01

    Kumu Kunstimuuseumis avatud 15. Tallinna Graafikatriennaali "Armastuse, mitte raha pärast" Grand Prix saanud Edmunds Jansonsi (Läti) animeeritud dokumentaalfilmist "Väikese linnukese päevik" (2007). Kolm võrdset preemiat pälvinud Antonio Claudio Carvalho (Brasiilia), õde Mary Corita (Corita Kent, 1918-1986, USA) ja Alina Rudnitskaja (Venemaa) töödest. Eripreemiate saajad. Oliver Laas sai ERKF Olev Soansi mälestusfondi stipendiumi

  18. Minutes of the Explosives Safety Seminar (25). Volume 4. Held in Anaheim, California on 18-20 Aug 1992

    Science.gov (United States)

    1992-08-01

    MARTIN MARIETTA ASTRONAUTICS CAPTAIN BARATTA GARY HAWTHORNE ARMY AMMUNITION PLANT MR. BARBERO LUIS CLAUDIO COELLO, 124 MR. BARNETTE JERRY MARINE CORPS...NEW MEXICO INSTITUTE OF MINING MR. TEO KIAN CDC CONSTRUCTION & DEVELOPMENT PTE LTD 640 MR. THOMAS JOSEPH HAWTHORNE ARMY AMMUNITION PLANT MR. THOMPSON...WILLIS RICHARD NORTHORP CORPORATION MR. WILSON NATHANIEL ARMAMENT RESEARCH, DEVELOPMENT AND MR. WINDSOR MARVIN NAVAL AIR WARFARE CENTER MR. WINGATE MARK

  19. Journal of the School of Naval Warfare (Revista da Escola de Guerra Naval)

    Science.gov (United States)

    2008-06-01

    APPROACHES - Captain (Ret) Claudio Rogeriod de Andrade Flor BOOK REVIEW HISTORIA DAS GUERRAS - Captain (Ret) Joaquim Arine Bacelar Rego 14. SUBJECT...reflected in the democratic voting system, i.e., each state is entitle to one vote. Obviously, these two cultural legacies arc inherently controversial...Japan joining the Council. A group of states - called "United for Consensus"- consisting of Pakistan, Argentina, Canada, Italy and Mexico support

  20. Counterinsurgency in Brazil: Lessons of the Fighting from 1968 to 1974

    Science.gov (United States)

    2010-01-01

    1964-1967): The organisms of spying and repression),” Quoted in Vestígios do Passado. Ampuh, RS: Associacao Nacional de Historia, 2008. http...http://www.estadao.com.br/ nacional /not_nac102644,0.htm (accessed January 09, 2010). 57 Lima, Claudio de...Castro. “O Brasil na Operação Condor (Brazil in Condor Operation). Aventuras na Historia,” Abril online, http://historia.abril.com.br/ politica /brasil

  1. Music in Galileo's Time

    Science.gov (United States)

    Petrobelli, P.

    2011-06-01

    Claudio Monteverdi appears as the key personality of the music in Galileo's time. His revolution in format and function of the musical language-from an essentially edonistic creation of purely sonorous images to a musical language consciously "expressive" of the content of the words on which it is based-is similar in character to the influential innovations in scientific thinking operated by Galileo.

  2. Publications 2007

    Directory of Open Access Journals (Sweden)

    2008-04-01

    Full Text Available Acerbi Fabio- Euclide, Tutte le Opere. A cura di F. Acerbi. Milano, Bompiani 2007, 2713 p.- « Una scuola matematica alessandrina ? »,, in C. Bartocci, P. Odifreddi (éds., La Matematica, Vol. 1. I luoghi e i tempi. Torino, Einaudi 2007, pp. 65-89.Comptes-rendus- H.L.L. Busard, Campanus of Novara and Euclid's Elements, Stuttgart, Franz Steiner Verlag 2005, in : Nuncius 22 (2007, pp. 139-140.- J. Evans, J.L. Berggren (éds., Geminos’s Introduction to the Phenomena: A Translation and Study of a...

  3. Publications 2009

    Directory of Open Access Journals (Sweden)

    2011-03-01

    Full Text Available Fabio Acerbi- « The Meaning of plasmatikovn in Diophantus’ Arithmetica », Archive for History of Exact Sciences 63 (2009, p. 5-31.- « Transitivity Cannot Explain Perfect Syllogisms », Rhizai 6 (2009, p. 23-42.- « Osservazioni sulle origini aritmetiche della teoria aristotelica del sillogismo ». In M. Alessandrelli, M. Nasti De Vincentis (éds., La logica nel pensiero antico. Atti del colloquio Roma 28-29 novembre 2000. Napoli, Bibliopolis 2009, p. 77-104.- « Une école mathématique alexandri...

  4. Design and creating model and interactive presentation of GEM for Microcosm Exhibition

    CERN Document Server

    Lakdee, Natthaphop

    2017-01-01

    GEM or Gas Electron Multiplier is the newer and easier way to amplify electron signal than conventional CSS. It was first created by Fabio Sauli at CERN in 1997 and was developed to get better efficiency over time. Right now, it was brought to use in many detector stations at CERN. To make GEM more publicly known, one of the ways is show in Microcosm Exhibition which is always visited by people from around the world everyday, so my main project as summer student is to design and create the model and interactive presentation which make GEM interesting and easy to understand by ordinary people.

  5. 精品赏析

    Institute of Scientific and Technical Information of China (English)

    欧南

    2014-01-01

    <正>瓦格纳《众神的黄昏》Richard Wagner-Gotterdammerung演唱:德波拉·弗艾特(Deborah Voigt)杰·亨特·莫里斯(Jay Hunter Morris)艾恩·帕特森(Lain Paterson)汉斯-彼得·金(Hans-peter Konig)温蒂·布莱恩·哈默(Wendy Bryn Harmer)伴奏:大都会歌剧院管弦乐团(The Metropolitan Opera Orchestra)指挥:法比奥·路易西(Fabio Luisi)编号:0440 073 4842(2DVD)

  6. Publications 2011

    Directory of Open Access Journals (Sweden)

    2012-03-01

    Full Text Available Fabio AcerbiDiofanto, “De polygonis numeris”. Introduzione, testo critico, traduzione italiana e commento di F. Acerbi», Pisa, Roma, Fabrizio Serra Editore, 2011. 252 p. Dany Amiot- [avec Dejan Stosic], « Sautiller, voleter, dansoter : évaluation, pluriactionnalité, aspect », Temps, aspect et classes de mots : études théoriques et didactiques. Actes du septième colloque international de linguistique française et roumaine, E. Arjoca-Ieremia, C. Avezard-Roger, J. Goes, E. Moline & A. Tihu (...

  7. Bellefontaine维美源素 北京新光天地闪亮登场

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    2009年7月18日,源自瑞士皇家殿堂级护肤品-Bellefontaine维美源素在北京新光天地盛大开幕,出席剪裁的矗亮有瑞士驻华大使参赞Claudio Mezzucchelli、驻中国瑞士旅游局局长Simon Bosshert、Bellefontaine瑞士总经理Mr Peter Yip、新光天地总经理甘添信、新光天地营业部部长朱元龙以及彩星赵雅芝等。

  8. La muerte como discurso retórico en algunos textos religiosos novohispanos

    OpenAIRE

    Rubial García, Antonio

    2012-01-01

    El estudio de la muerte como discurso retórico en algunos textos novohispanos diseña un escenario más para la investigación para mostrar cómo los autores religiosos novohispanos percibieron retóricamente la muerte en distintos tipos de narración. El tema se ha estudiado desde la antropología e investigadores como Claudio Lomnitz han encontrado contradicciones entre la visión cristiana y la imposición de una nueva concepción del estado a partir de la conquista.

  9. Network innovation through OpenFlow and SDN principles and design

    CERN Document Server

    Hu, Fei

    2014-01-01

    FUNDAMENTALSSDN /OpenFlow: Concepts and Applications; Ashley Gerrity and Fei HuAn OpenFlow Network Design Cycle; Pedro A. Aranda Gutiřrez and Diego R. LopezDESIGNIP Source Address Validation Solution with OpenFlow Extension and OpenRouter; Jun BiLanguage and Programming in SDN /OpenFlow; Muhammad Farooq and Fei HuControl and Management Software for SDNs; Natalia Castro Fernandes and Luiz Claudio Schara MagalhêsController Architecture and Performance in Software-Defined Networks; Ting Zhang and Fei HuMobile Applications on Global Clouds Using OpenFlow and Software-Defined Networking; Subharth

  10. NX15 science workshop

    CERN Multimedia

    2015-01-01

    Science. For some of us, it's daunting or maybe even terrifying. How to tell a good science story? That's the question we will explore together in this workshop. Conceived and produced by journalist and Scientific News producer Claudio Rosmino of Euronews, and presented by Euronews' Jeremy Wilks, the workshop will look at actual case studies (from Euronews and beyond) where science news proved exciting, inspiring and accessible to audiences around the world. These might include the Rosetta mission and CERN's work on Science for Peace. Together, we'll share ideas and knowledge around how science journalism and science news can increase its visibility in the media and maybe save the planet...!

  11. Reconstrucción Infográfica del Castellum de Tamuda (Tetuán, Marruecos

    Directory of Open Access Journals (Sweden)

    Javier Bermejo Meléndez

    2012-11-01

    Full Text Available The last researches developed in the lot of Tamuda's Roman castellum (Tetuan, Morocco, specially centred on the doors of the military installation, have emphasized different phases or constructive episodes in the life of the same one. This way in this work they present diverse restitutions infographics corresponding to the phases documented in the enclosure, centred of a specific way in the doors of access, offering an image of the evolution of the above mentioned military installation throughout almost four centuries, from the moments of the foundation in epoch of Claudio up to the beginnings of Vst. c. A.D.

  12. The size and shape of Dante's Purgatorio

    Science.gov (United States)

    Magnaghi-Delfino, Paola; Norando, Tullia

    2015-07-01

    Where is Mount Purgatory? How high is it? How large is the island upon which it was situated? In the previous century Rodolfo Benini and Ideale Capasso developed a series of hypothesis and calculations to find answers to these questions. Each used data derived from mathematics, astronomy, history of science and cartography, but they completely disagreed on the location and on the overall size and shape of the island. In this paper we review the main points of these two scholars, then we rework the calculations and estimates, according with a new astronomical hypothesis presented by Giulio Magli and Claudio Facciolo.

  13. Análisis de los flujos de tránsito en una calle peatonal

    OpenAIRE

    Lobos Collantes, Fernando

    2015-01-01

    Resumen: La calle Santiago es la calle más céntrica y una de las más comerciales de Valladolid. En este TFG se analiza el comportamiento del flujo de peatones en la calle Santiago a su paso por el cruce con la calle Claudio Moyano mediante técnicas estadísticas avanzadas basadas en datos funcionales como clustering, Análisis de Componentes Principales (ACP) o Análisis de la Varianza (ANOVA). También se estudiará la efectividad del semáforo inteligente ubicado en el cruce en la reducción del t...

  14. [Gout and its manifestations, description and treatment in ancient times].

    Science.gov (United States)

    Alušík, Tomáš; Alušík, Štefan

    2015-01-01

    Gout is a very old disease, which exists for thousands of years. The first descriptions interpreted as the symptoms of gout can be found already in the Egyptian medical papyri dating to the 3rd mill. BC. In the Ancient world, many physicians dealt with the causes, diagnostics and the treatments of gout, such as Hippocrates of Cos, Diocles of Carystus or Claudios Galenos. A personified gout (as the goddess Podagra) is also to be found in the Ancient mythology and culture. Several human remnants of the people suffering from gout are preserved from the Antiquity as well.

  15. Buenos Aires 1977. Crónica de una fuga.

    Directory of Open Access Journals (Sweden)

    Moira Cristiá

    2007-11-01

    Full Text Available La tragedia de numerosas familias argentinas y la guerra silenciosa que vivió una sociedad palpitante de violencia y plena de sueños que se escurrían entre sus dedos, se hace palpable en una experiencia particular, a la manera de un estudio de microhistoria. El argumento del film, inspirado en un acontecimiento verídico, es la adaptación al cine del libro autobiográfico de Claudio Tamburrini “El pase libre. La fuga de la mansión Seré”. El protagonista es un estudiante y arquero de fútbol que...

  16. Historia de la Cátedra de Terapeútica, Materia Médica y Arte de Recetar de la Facultad de Medicina de la Universidad de Valladolid: Periodo 1857-1905r

    OpenAIRE

    Velasco Sendra, Alfonso

    2012-01-01

    La Facultad de Medicina de la Universidad de Valladolid fue recuperada en 1857 gracias a las gestiones de Don Claudio Moyano Ministro de Fomento. Durante este periodo la cátedra fue desempeñada por Don Cristóbal Dámaso García, Don Eugenio Alau Comas, Don Agustín Morte Gómez, Don Victoriano Díez Martín, Don Silvestre Cantalapiedra Hernández y Don Raimundo García Quintero. Para elaborar este trabajo se han revisado los expedientes y documentos de cada uno de los profesores proced...

  17. TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport

    OpenAIRE

    Schmidts, M.; Hou, Y.; Cortés, CR; Mans, DA; HUBER, C; Boldt, K.; Patel, M.; Van Reeuwijk, J; Plaza, JM; Van Beersum, SEC; Yap, ZM; Letteboer, SJF; Taylor, SP; Herridge, W.; Johnson, CA

    2015-01-01

    ARTICLE Received 1 Oct 2014 | Accepted 31 Mar 2015 | Published 5 June 2015 TCTEX1D2 mutations underlie Jeune asphyxiating thoracic dystrophy with impaired retrograde intraflagellar transport Miriam Schmidts1,2,3,4,*, Yuqing Hou5,*, Claudio R. Corte´s6, Dorus A. Mans2,3, Celine Huber7, Karsten Boldt8, Mitali Patel1, Jeroen van Reeuwijk2,3, Jean-Marc Plaza9, Sylvia E.C. van Beersum2,3, Zhi Min Yap1, Stef J.F. Letteboer2,3, S Paige Taylor10, Warren Herridge11, Colin A. Johns...

  18. Empoderar: nuevo concepto de liderazgo para el administrador educativo

    OpenAIRE

    Luis Enrique González Salazar

    2001-01-01

    En este artículo se realiza un análisis de las dosdirectrices enviadas por el Dr. Claudio Gutierrez cuandofue Ministro de Educación, en las que se empoderaba alas direcciones regionales de educación y se ponía en prác-tica el principio de subsidiaridad, para establecer unanueva manera de relacionar las direcciones regionalescon las oficinas centrales del Ministerio y éstas con las Ins-tituciones Educativas. Se enfatiza en el potencial de esteconcepto de liderazgo con el objeto de analizar el ...

  19. Fronteira, fusão, filme: um toque

    Directory of Open Access Journals (Sweden)

    Tunico Amancio

    2010-12-01

    Full Text Available Considered the first co-production between MERCOSUR countries, "The touch of the Oboe", a film by Claudio MacDowell, suffers from some sort of vagueness that shows off the difficulties of a complete commercial and cultural movie exchange between Brazil's neighbor countries. Even bolstered with powerful traditions, the productive associative project of this cinematic realization emblematizes an economical, symbolical and historical imbalance which still prevails among the countries of the Southern Common Market. The text notes some of these tensions, marked by the relationship between cinema and literature.

  20. ‘‘I think that the small peptides are the best for healthy ageing…’’, an interview with Vladimir Khavinson

    DEFF Research Database (Denmark)

    Rattan, Suresh

    2013-01-01

    Since its inception in 2000, Biogerontology has published interviews with some of the most renowned and intellectually influential biogerontologists, including Len Hayflick, Robin Holliday, Denham Harman,VincentCristofalo, Claudio Franceschi, Leslie Robert, Ken Kitani, Geroge Martin, Zhores...... Medvedev and John Maynard Smith. These interviews have explored the minds of these scientists in all aspects of their lives combining the private and the professional. Together, this series is a remarkable document providing an insight into the history of ideas in modern biogerontology. Here we present...

  1. Edificio de oficinas en Roma

    Directory of Open Access Journals (Sweden)

    Decker, Emilio

    1962-06-01

    Full Text Available El edificio, construido en colaboración por los arquitectos e ingenieros Emilio y Claudio Decker, Giancarlo Nale y Domenico Virgili, está edificado sobre un solar de unos 3.300 m2, con la fachada principal a la calle Lungotevere Arnaldo da Brescia, entre las Vías Mancini y Scialoja, y paralelo a la arteria de mayor tráfico. En su planteamiento se han previsto las más óptimas posibilidades de estacionamiento de automóviles, factor de suma importancia para el mejor servicio de las oficinas.

  2. Acercamientos a la ciencia ficción

    Directory of Open Access Journals (Sweden)

    Diego Vicente Rodríguez Hillón

    2015-01-01

    Full Text Available El presente artículo es un capítulo de la tesis en proceso de la Maestría en Literatura de la Universidad Pedagógica y Tecnológica de Colombia (UPTC, titulada Ciencia ficción colombiana y Modernidad: una lectura de tres obras de la primera mitad del siglo XX . El texto busca en un inicio ofrecer una definición del género como una fantasía plausible para posteriormente estudiar sus características y desarrollo a través de algunas propuestas de Claudio Guillén.

  3. De regreso a Oktubre

    OpenAIRE

    Solari, Carlos Alberto; Beilinson, Eduardo Alberto; Ideal,, E.; Villelisa; Tranquilo Enano; Don Lunfardo y el Señor Otario; López Camelo, Fernanda; Negusa Negast; Crema del Cielo; Mostruo!; Sr. Tomate; Encías Sangrantes; Heguiabere, Hernán

    2007-01-01

    Una producción de FM 107.5 Radio Universidad de La Plata. Grabado, mezclado y masterizado por Alfredo Calvelo en Estudios Hollywoodvvv. Concepto e ilustración de tapa: Juan Soto. Diseño gráfico: Kubilai Medina. Agradecimientos a Rocambole, al Chivo, a Efraín, Gustavo y Patricio de Ultrapop, a Flavio Mamini de Grafikar, Martín Boneto, Gloria Guerrero, Pablo Strozza, Eddie Babenco, Francisco Lagomarsino, Mariel Zabiuk, Alejandro Lingentti, Tom Lupo, Nicolás Miguelez, Claudio Kleima...

  4. "The Anatomy of the Bond Market Turbulence of 1994"

    OpenAIRE

    Claudio E.V. Borio; McCauley, Robert N.

    1996-01-01

    According to Claudio E. V. Borio and Robert N. McCauley, "the bond market sell-off of 1994 has begun to show up on lists of market events against which risk management systems are judged." Examples of other such events are the 1987 stock market crash and the 1995 Kobe earthquake. However, there has been little analysis of the cause of the 1994 decline. Borio and McCauley fill the void by examining a number of factors that might explain the rise in volatility during that year. The authors inve...

  5. Unraveling mulitple translatorship through an e-mail correspondence

    DEFF Research Database (Denmark)

    2017-01-01

    The aim of this study is to shed light on questions of “multiple translatorship” and particularly on translation collaboration processes. The empirical material consists of more than three hundred e-mails exchanged between two co-translators who translated Claudio Magris’s novel Alla cieca (2005......) into Danish. The theoretical framework presents a double perspective through which the e-mail correspondence is studied: on the one hand, as an ethnographic “thick description” (focusing on translation as an event), with the aim of uncovering who the agents involved are, how they interact, and what...

  6. PRÁTICAS MUSICAIS, REDES DE SOCIABILIDADE E CULTURA INTELECTUAL NA CORRESPONDÊNCIA ENTRE FRANCISCO CURT LANGE E CLÁUDIO SANTORO -1940/1946. (Dossiê: Música, Linguagem e Sociedade.

    Directory of Open Access Journals (Sweden)

    Loque Arcanjo Junior

    2016-09-01

    Full Text Available Resumo: São diversos os personagens do nacionalismo musical brasileiro que trocaram cartas com o musicólogo alemão radicado no Uruguai, Francisco Curt Lange, (1903-1997. A proposta da primeira etapa da pesquisa da qual este artigo é resultado se concentrou no estudo das cartas inéditas trocadas entre Curt Lange e o mais renomado modernista brasileiro, Mário de Andrade. O ineditismo destas cartas, ainda não utilizadas como objeto de pesquisa até aquele momento, demonstrou a relevância desta investigação que ainda está em andamento. Apesar do foco da primeira etapa se concentrar nas cartas trocadas entre Lange e Mário de Andrade, durante a pesquisa, diversos outros atores tais como, Villa-Lobos, Camargo Guarnieri, Guerra-Peixe, Koellreuter e Claudio Santoro apareceram dentro de uma rede de sociabilidades tecida pelo projeto musicológico de Curt Lange: o Americanismo Musical. A ampliação do estudo desta rede se concentra agora nas cartas trocadas entre Curt Lange e Cláudio Santoro (1919-1989. O presente artigo trata daquelas cartas trocadas entre os anos nos de 1942 e 1946 e os diálogos estas com esta rede mais ampla. Este é um momento decisivo para a vida musical de Claudio Santoro, pois este procurava se estabelecer como compositor em meio aos nacionalismos que emergiam num contexto político e cultural bastante significativo para a história da música no Brasil. Palavras-chaves: Prática missivista, nacionalismos, governo VargasAbstract: There are several characters from the Brazilian musical nationalism exchanged letters with the German musicologist living in Uruguay, Francisco Curt Lange (1903-1997. The proposal of the first stage of the research on which this article is a result focused on the study of unpublished letters exchanged between Curt Lange and the most renowned Brazilian modernist Mário de Andrade. The novelty of these letters, not yet used as a research object, until that time, demonstrated the relevance of

  7. ALICE presents its first award to Industry

    CERN Multimedia

    Maximilien Brice

    2003-01-01

    Behind from left to right (Derrière de gauche à droite): Bernardo Mota, member of the ALTRO design team, Jurgen Schukraft, ALICE Spokesperson, Luciano Musa, leader of the ALTRO Design Team and Coordinator of the ALICE TPC FEE, Roberto Camapagnolo, member of the ALICE TPC FEE team, Jean-Pierre Coffin, Deputy of the ALICE Collaboration Board Chairman, Hans de Groot ALICE Resource Coordinator, Laurent Degoujon, ST - Data Converter Design Manager, Claude Engster, member of the ALICE TPC FEE team, Alain Delpi, ST - Data Converter Business Unit Manager, Carmen Gonzalez, member of the ALICE TPC FEE team, Yiota Foka, ALICE Outreach Coordinator; Front: Fabio Formenti , EP-ED Group Leader, Juan Antonio Rubio, ETT Division Leader.

  8. Margarita Peña, Juan Ruiz de Alarcón ante la crítica, en las colecciones y en los acervos documentales, Benemérita Universidad Autónoma de Puebla/Universidad Autónoma Metropolitana/Miguel Ángel Porrúa, México, 2000, 324 pp.

    OpenAIRE

    Vallejo Cervantes, Gabriela

    2005-01-01

    Dentro de la larga bibliografía alarconiana, el libro de Margarita Peña hace una verdadera contribución. Figura señera de la historia literaria del teatro del Siglo de Oro, Juan Ruiz de Alarcón ha sido uno de los dramaturgos más estudiados desde el siglo XVIII. A partir de la publicación de sus comedias en 1628 (Madrid, por Juan González) y 1634 (Barcelona, por Sebastián Comellas) hasta los primeros comentarios de Fabio Franchi (siglo XVII, en las Exequias poéticas a la muerte de Lope) y de P...

  9. Central blood pressure assessment using 24-hour brachial pulse wave analysis

    Directory of Open Access Journals (Sweden)

    Muiesan ML

    2014-10-01

    Full Text Available Maria Lorenza Muiesan, Massimo Salvetti, Fabio Bertacchini, Claudia Agabiti-Rosei, Giulia Maruelli, Efrem Colonetti, Anna Paini Clinica Medica, Department of Clinical and Experimental Sciences, University of Brescia, Brescia, Italy Abstract: This review describes the use of central blood pressure (BP measurements during ambulatory monitoring, using noninvasive devices. The principles of measuring central BP by applanation tonometry and by oscillometry are reported, and information on device validation studies is described. The pathophysiological basis for the differences between brachial and aortic pressure is discussed. The currently available methods for central aortic pressure measurement are relatively accurate, and their use has important clinical implications, such as improving diagnostic and prognostic stratification of hypertension and providing a more accurate assessment of the effect of treatment on BP. Keywords: aortic blood pressure measurements, ambulatory monitoring, pulse wave analysis

  10. Academic Training Lecture Regular Programme: Predictive Monte Carlo tools for LHC physics (1/3)

    CERN Multimedia

    2012-01-01

    Predictive Monte Carlo tools for LHC physics (1/3), by Fabio Maltoni (Université Catholique de Louvain (BE)).   Wednesday, May 2, 2012 from 11:00 to 12:00 (Europe/Zurich) at CERN ( 503-1-001 - Council Chamber ) Simulations of events taking place at the LHC play key role in all experimental analyses. Starting from the basics concepts of QCD, we first review how accurate predictions can be obtained via fixed-order calculations at higher orders. Parton showers and event generation are then introduced as a means to achieve fully exclusive predictions. Finally  the recent merging and matching  techniques between fixed-order and fully exclusive simulations are  presented, as well as their implementations via the MLM/CKKW and MC@NLO/POWHEG methods. Organised by Mario Campanelli. More information here.

  11. Discovery Mondays - 'Eureka! Meet the inventors'

    CERN Multimedia

    2006-01-01

    Fabio Sauli, the inventor of the GEM detector. Do you imagine an invention as a spontaneous brainchild emergi from the convoluted mind of some scatterbrained and dishevelled scientist? If so, you are mistaken! Join us at Microcosm for the next Discovery Monday at which inventors will be the guests of honour. There you will meet scientists who, thanks to their creativity, have made technological progress possible. By constantly rising to new scientific and technological challenges, CERN has delivered numerous innovations, particularly in the medical field. Members of the Crystal Clear collaboration and the inventor of the GEM detector will give talks about their innovations and their applications, in particular for medical purposes. You will also be able to speak to members of the Medipix collaboration, which is working on improvements to X-ray and gamma ray imaging techniques. The event will be conducted in French. Come to Microcosm, (Reception Building 33, Meyrin site), on Monday 6 February from 7.30 p...

  12. 17 años de “Tribus urbanas”

    OpenAIRE

    Magallón Martínez, Roberto Carlos

    2013-01-01

    El presente artículo presenta las entrevistas realizadas a los autores del libro “Tribus Urbanas: El ansia de identidad juvenil: entre el culto a la imagen y la autoafirmación a través de la violencia”, los profesores de la Universidad Autónoma de Barcelona, Pere Oriol Costa, José Manuel Pérez Tornero, Fabio Tropea y Charo Lacalle. Resume así las opiniones de éstos sobre una posible evolución en el comportamiento y el ser de las tribus urbanas a 17 años de la publicación del libro. The fol...

  13. I reati culturalmente motivati: la cultural defense in alcune sentenze statunitensi

    Directory of Open Access Journals (Sweden)

    Carlo Sorio

    2011-06-01

    Full Text Available Il contributo è segnalato dal Prof. Fabio Basile.SOMMARIO: 1. Cenni preliminari sulla c.d.cultural defense - 2. Sentenze in cui sidà rilievo allacultural defense - 2.1. Assoluzione - 2.1.1. People v. Metallides (1974 -2.1.2. State v. Kargar (1993 - 2.1.3. State v. Krasniqi (1989-1992 - 2.2. Derubricazionedel reato e/o riduzione della pena - 2.2.1. People v. Kimura (1975 - 2.2.2. People v.Poddar (1969-1974 - 2.2.3. People v. Moua (1985 - 2.2.4. People v. Chen (1987 - 3.Sentenze in cui si nega rilievo allacultural defense - 3.1. People v. Romero (1999 -3.2. People v. Rhines (1982 - 3.3. People v. Aphaylath (1986 - 3.4. Siripongs v.Calderon (1994 - 4. Riflessioni conclusive.

  14. Elections to the Senior Staff Advisory Committee (“The Nine”) 2015

    CERN Multimedia

    Tim Smith, ex-spokesperson of the "Nine"

    2015-01-01

    The electronic voting process for the Senior Staff Advisory Committee (“The Nine”) was closed on Friday 28 August 2015 at 17:30.   Of the 526 Senior Staff members eligible to vote, 275 voted. This represents a participation of 52%, to be compared to 59% in 2014, 63% in 2013, 61% in 2012, 43% in 2011, 44% in 2010, 57% in 2009, 53% in 2008, 63% in 2007, 64% in 2006 and 66% in 2005. The results are:   Electoral group 2 (Applied Physicists, Engineers, Computer Scientists) Candidate Dept Votes Result Sergio CALATRONI TE 50   Marco CATTANEO PH 76 ELECTED Maria DIMOU IT 44   Fabio FORMENTI TE 51   John JOWETT BE 68   Maarten LITMAATH IT 26   John SHADE IT 28   Raymond VENESS BE 103 ELECTED Payol VOITYLA DGS 12   Maurizio VRETENAR DG 100 ELECTED   Electoral group 3 (Administration, Human Resource...

  15. Gestalt psychology in Italy.

    Science.gov (United States)

    Verstegen, I

    2000-01-01

    Graz gestalt psychology was introduced into Italy after World War I with Vittorio Benussi's emigration to Padua. His earliest adherent, Cesare Musatti, defended Graz theory, but after Benussi's premature death became an adherent of the Berlin gestalt psychology of Wertheimer-Köhler-Koffka. He trained his two most important students, Fabio Metelli and Gaetano Kanizsa, in orthodox Berlin theory. They established rigid "schools" in Padua and Trieste. The structure of Italian academics allowed for such strict orthodoxy, quite unlike the situation in America, where scientific objectivity mitigated against schools. In the 1960s, some of the students of Metelli and Kanizsa (above all Bozzi) initiated a realist movement-felt in Kanizsa's late work-that was quite independent of that of J. J. Gibson. Finally, more recently, Benussi and Graz theorizing have been embraced again, sentimentally, as a predecedent to Kanizsa-Bozzi.

  16. Publications 2008

    OpenAIRE

    2009-01-01

    Fabio Acerbi- « Euclid’s Pseudaria », Archive for History of Exact Sciences 62 (2008), pp. 511-551. - « Conjunction and Disjunction in Euclid’s Elements », Histoire, Épistémologie, Langage, 30, 2008, pp., 21-47. - Entrées : « Apollonius of Perga », « Archimedes », « Damianus of Larissa », « Hero of Alexandria », « Hypatia », in : N. Koertge (ed.), New Dictionary of Scientific Biography, Detroit, Ch. Scribner's Sons, 2008, vol. I, pp. 83-85 ; 85-91 ; 233-234 ; 283-286 ; 435-437. - « The meanin...

  17. Publications 2008

    Directory of Open Access Journals (Sweden)

    2009-02-01

    Full Text Available Fabio Acerbi- « Euclid’s Pseudaria », Archive for History of Exact Sciences 62 (2008, pp. 511-551.- « Conjunction and Disjunction in Euclid’s Elements », Histoire, Épistémologie, Langage, 30, 2008, pp., 21-47.- Entrées : « Apollonius of Perga », « Archimedes », « Damianus of Larissa », « Hero of Alexandria », « Hypatia », in : N. Koertge (ed., New Dictionary of Scientific Biography, Detroit, Ch. Scribner's Sons, 2008, vol. I, pp. 83-85 ; 85-91 ; 233-234 ; 283-286 ; 435-437.- « The meaning o...

  18. Staff members with 25 years’ service at CERN in 2009

    CERN Multimedia

    HR Department

    The 62 staff members who are celebrating 25 years' service at CERN in 2009 were invited by the Director-General to a reception in their honour on 17 November. ARNAUDON Luca/BE BEL Jean-François/TE BERTINELLI Francesco/TE BLAND Alastair/BE BLOCH Philippe/PH BORCIER Luc/EN BRUNEL Xavier/PH BURKIMSHER Paul/EN CAMPI Domenico/PH CATTAI Ariella/PH DALIN Jean-Michel/EN DANGOISSE Claude/IT DAVIDS Daniel/EN DI MAIO Franck/BE FERRARI Claude/EN FISCHER Klaus/TE FOLLEY Adrian/PH FORMENTI Fabio/TE GATIGNON Laurentius/EN GIACHINO Rossano/BE GONIDEC Allain/PH GRAFSTROM Per/PH HANCOCK Steven/BE HATCH Mark/PH HEMMER Frederic/IT HOURICAN Michael/TE ...

  19. Publications 2010

    Directory of Open Access Journals (Sweden)

    2011-06-01

    Full Text Available Fabio Acerbi- Il silenzio delle sirene. La matematica greca antica, Roma, Carocci 2010, 448 p.- « Homeomeric Lines in Greek Mathematics », Science in Context 23 (2010, p. 1-37.- « Two Approaches to Foundations in Greek Mathematics: Apollonius and Geminus », Science in Context 23 (2010, p. 151-186.- [avec N. Vinel, B. Vitral], « Les Prolégomènes à l’Almageste. Une édition à partir des manuscrits les plus anciens : Introduction générale, Parties I-III », SCIAMVS 11 (2010, p. 53-210.- « The G...

  20. Cell scientist to watch - Gaia Pigino.

    Science.gov (United States)

    2017-03-15

    Gaia Pigino received her master's degree in natural science followed by a PhD in evolutionary biology - focusing on zoology and ecotoxicology - in the laboratory of Fabio Bernini at the University of Siena, Italy. She then joined the electron microscopy laboratory of Pietro Lupetti for her first postdoctoral position before moving to Zürich. There, supported by an EMBO Long-Term Fellowship, she worked with Takashi Ishikawa at the Swiss Federal Institute of Technology and the Paul Scherrer Institute in Villigen. In 2012, Gaia became an independent group leader at the Max Planck Institute in Dresden. Her laboratory is interested in understanding the assembly of the cilium and mechanisms of ciliary transport in eukaryotic cells, as investigated with cryo-transmission electron microscopy.

  1. IEEE NUCLEAR SCIENCE SYMPOSIUM AND MEDICAL IMAGING CONFERENCE 15-20 OCTOBER 2000 PALAIS DES CONGRES, LYON, FRANCE

    CERN Multimedia

    2000-01-01

    The IEEE NSS & MIC will be held this year in Europe for the first time in its more than 40 year history. Some 280 oral and 400 poster presentations on radiation detectors, instrumentation and imaging will be given over the five days of the conferences. In addition there is a rich programme of keynote talks, topical workshops, short courses and an industrial exhibition with more than 50 exhibitors. SHORT COURSES Following a long and successful tradition, several tutorial short courses, delivered by known experts in the specific fields, are being offered to registered students. There are still places available to attend the courses on Solid State Detectors, Particle Identification and Detectors for Astrophysics. These intensive one-day tutorials will be given on Sunday October 15. Full details and registration information can be found on the conference web site or from the Short Courses Organiser, Fabio Sauli, CERN. A limited amount of financial support is available for motivated scholars who may not ot...

  2. SEXUALITY IN THE OPINION OF ADOLESCENTS LIVING IN THE AREA OF COVERAGE IN DR FÁBIO CUIABÁ CITY, BRAZIL

    Directory of Open Access Journals (Sweden)

    Sebastião Junior Henrique Duarte

    2011-04-01

    Full Text Available Quantitative study aimed to know the understanding of adolescents about their sexuality and how the exercises for further intervention by the health team. We administered a structured questionnaire in a sample of 43 adolescents aged 12 to 19 years living in the area covered by the Family Health Unit Dr. Fabio I and II. The data were tabulated in the spreadsheet program Microsoft Office Excel 2007, allowing for a descriptive treatment, keeping a confidence interval of 95%. The results show that 32.5% of participants had first intercourse between 12 and 16, and 50% of them admit they have used a condom at last intercourse. In addition, 4.6% have had some kind of sexually transmitted disease. The study indicates the need for educational activities in sexual and reproductive health to adolescents facing the neighborhoods studied, with a view to promoting health.

  3. Ramón Cote Baraibar

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    Juan Gustavo Cobo Borda

    2005-05-01

    Full Text Available Hijo de poeta, como María Mercedes Carranza y Santiago Mutis, Ramón Cote nació en Cúcuta el 19 de mayo de 1963- Su primer libro fue publicado en 1984 por ediciones Arnao, de Madrid, donde se graduó en historia del arte en la Universidad Complutense. Al instalarse en Colombia, se dedicó a la publicidad. Ha publicado ensayos sobre poesía colombiana en revistas como ínsula, y en 1992, con el título de  |Diez de ultramar publicó una muestra de joven poesía latinoamericana que abarcaba nombres como José Luis Rivas, Coral Bracho, Raúl Zurita, Fabio Morabito, Yolanda Pantin y Eduardo Chirinos. Entre la nueva poesía colombiana, su voz es una de las más reconocibles. Vale la pena, entonces, repasar la totalidad de su trayectoria.

  4. A encruzilhada entre rua e internet: redes sociais como fator de mobilização de manifestações brasileiras em 2013

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    Mirian Aparecida Meliani Nunes

    2015-06-01

    Full Text Available The crossroads between the streets and the internet: social networks as a mobilizing factor for the Brazilian demonstrations in 2013 - Fabio Malini and Henrique Antoun are researchers and political activists. They wrote a book under the heat of the manifestations that took the streets of major Brazilian cities, in June 2013. They released their book in August, only two months after the heyday of the movement, reaching a speed that set, at the same time, the strength and limits of the work. They begin their narrative summarizing the history of cyberspace and cyberculture, and discover a meeting place between the streets and digital networks, a phenomenon capable of mobilizing and drawing new routes for political action.

  5. Le Mouvement Socialavril –juin 1999, n° 187Périphéries et centres/ Enseignants et syndicalisme

    OpenAIRE

    Soufi, Fouad

    2013-01-01

    Le local et le national, le centre et la périphérie analysés à partir de la question sicilienne (1861-1876) par Jean-Louis Briquet et de l’organisation de l’espace social dans le village de Tepoztàn au Mexique par Claudio Lomnitz, avec une présentation essentielle de Gilles Pécout. La seconde partie de la revue est consacrée au syndicalisme enseignant : la Fédération Unitaire de l’Enseignement entre 1919 et 1929 (Loïc Le Bras) d’une part et d’autre part, la syndicalisation des enseignants du...

  6. Financiamiento para las Micro y Pequeñas Empresas. Algunas Líneas de Acción

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    Janina León Castillo

    1998-06-01

    Full Text Available El presente artículo se basa en un documento más extenso: “The Promotion of Small and MicroEnterprises: A Source Book” preparado para el Banco Interamericano de Desarrollo (BID y la Fundación para el Desarrollo Sostenible (FUNDES, como Relatorio de la Conferencia Internacional “Crédito para la pequeña y la microempresa”, realizada en Washington D.C. en Junio, 1994. Los autores agradecen los comentarios de Douglas Graham y Claudio González Vega (The Ohio State University, Carlos Cuevas (Banco Mundial, Mark Flaming (BID, y Markus Reichmuth (FUNDES. Por supuesto, todo error u omisión es de nuestra entera responsabilidad. Muchas de las ideas planteadas en este artículo emergieron a inicios de la presente década, y su difusión está aún en proceso.

  7. CERN’s policy in the field of knowledge and technology transfer goes global

    CERN Multimedia

    CERN Bulletin

    On 2 November, the Knowledge & Technology Transfer (KTT) Group presented to the Directorate three proposals that aim to enhance KTT activities. One important aspect of the proposals is the direct involvement of all members of CERN, who are strongly encouraged to communicate any ideas for additional applications of their work. KTT is a high-priority activity area because of its potential to demonstrate the role of CERN as a source of innovation, delivering tangible benefits to society. In particular, through its know-how and its leadership, CERN is today generating innovations applicable in domains such as medical sciences, energy and the environment, as well as many others. “The measures endorsed by the Directorate on 2 November include a comprehensive policy for managing the intellectual property related to CERN technologies”, explains Claudio Parrinello, head of the KTT Group in the DG Department. “This includes a proposal to redistribute part of the income generated by ...

  8. Empoderar: nuevo concepto de liderazgo para el administrador educativo

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    Luis Enrique González Salazar

    2001-01-01

    Full Text Available En este artículo se realiza un análisis de las dosdirectrices enviadas por el Dr. Claudio Gutierrez cuandofue Ministro de Educación, en las que se “empoderaba” alas direcciones regionales de educación y se ponía en prác-tica el principio de subsidiaridad, para establecer unanueva manera de relacionar las direcciones regionalescon las oficinas centrales del Ministerio y éstas con las Ins-tituciones Educativas. Se enfatiza en el potencial de esteconcepto de liderazgo con el objeto de analizar el estadoactual del proceso de “empoderamiento” en la DirecciónRegional de Alajuela, visto este como un continuo entre laautonomía y el control en los estilos de liderazgo practica-do por los directores cinco del circuito 01

  9. Science.gov (United States)

    In life and work, Claudio Bunster prefers extreme challenges. Bunster, a physicist who contemplates brain-warping theories of space and time, returned to his native Chile from the United States precisely when most intellectuals would have stayed clear - during the middle of the Pinochet dictatorship. Shut out of the universities by the military government, he broke the conventional mold by founding a research institute that he then moved from Santiago, the capital, to Valdivia in southern Chile, against the flow of minds and money. He led the presidential science advisory committee during the administration of Eduardo Frei, and served on the Dialogue Board of Human Rights to reconcile Chilean military and civil society. For his achievements, Bunster was elected to the National Academy of Sciences in 2005. In his Inaugural Article, which appeared in the July 24, 2007 issue of PNAS [1], he showed that after a black hole swallows a magnetic monopole, the space-time singularity starts rotating.

  10. Reinforced concrete in Catalonia (1898-1929: four companies and their relationship with architecture

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    R. Graus

    2017-06-01

    Full Text Available Between 1898 and 1929 various business initiatives that introduced reinforced concrete in its architecture developed in Catalonia. This article studies the following four companies: Anónima Claudio Duran - Construcciones Monier, Marial Hermanos - Sociedad Colectiva, Construcciones y Pavimentos, S. A. and Material y Obras, S. A. Only thorough knowledge of the production complexities that studies these companies, their technicians and works in all its complexity will allow us to assess how reinforced concrete transformed the construction sector, with new companies of a different productive scale. However, the depressed economic cycle of 1929-1952 weighed down any initiative and artificially lengthened what was left of traditional “Catalan construction”.

  11. Su 1910. L'emancipazione della dissonanza: Per una retorica della gioventù

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    Niccolò Scaffai

    2014-05-01

    Full Text Available Pubblichiamo qui un saggio inedito di Thomas Harrison, Rhetoric of Youth, or Bridges to Nowhere, nel contesto di un numero che proprio alla retorica e ai suoi poteri è dedicato. Nell’articolo, Harrison riprende alcuni concetti e figure del suo volume 1910: The Emancipation of Dissonance, appena tradotto in Italia, dove è stato recensito fra gli altri da Claudio Magris (sul «Corriere della Sera» e da Valerio Magrelli (su «la Repubblica». Se pure con ritardo – in America il volume è apparso nel 1996 – il pubblico italiano ha oggi a disposizione un saggio intorno al quale si è raccolto il consenso di intellettuali e critici di area e formazione diverse.

  12. Technical Directors of Fineland with Experts of Codelco on the Road%与智利国营铜业围炉论道——山东方圆公司技术负责人与智利Codelco专家对话侧记

    Institute of Scientific and Technical Information of China (English)

    聂刚

    2011-01-01

    今年8月底,智利国营制业公司( Codelco)组织的专家考察闭一行,再次来到东营.行程早就定了,然而因为种种原因, 一拖再拖,终于两个月后成行.Claudio·Queirolo,Aquiles Veas,Patricio·Peralta三位实践型技术专家,从地球的另一端赶来了.他们此行目的很明确,就是为了与方圆的同行们坐下来,好好聊一下彼此在多年生产实践中感悟出来、积累下来的“铜理铜道”,相互学习,取长补短.

  13. "I think that the small peptides are the best for healthy ageing...", an interview with Vladimir Khavinson. Interview by Suresh I. S. Rattan.

    Science.gov (United States)

    Khavinson, Vladimir

    2013-02-01

    Since its inception in 2000, Biogerontology has published interviews with some of the most renowned and intellectually influential biogerontologists, including Len Hayflick, Robin Holliday, Denham Harman, Vincent Cristofalo, Claudio Franceschi, Leslie Robert, Ken Kitani, Geroge Martin, Zhores Medvedev and John Maynard Smith. These interviews have explored the minds of these scientists in all aspects of their lives combining the private and the professional. Together, this series is a remarkable document providing an insight into the history of ideas in modern biogerontology. Here we present Vladimir Khavinson talking about his life and work in Russia during and after the Soviet times, his ideas on stress and health, his discoveries of the healthy ageing promoting small peptides, and other anti-ageing interventions.

  14. Nuclear isoscaling and fair sampling

    Science.gov (United States)

    Lopez, Jorge

    2008-10-01

    The isoscaling phenomenon was first observed in nuclear multifragmentation experiments and has become a hot topic as it could provide a probe of the nuclear equation of state to understand nuclear matter at extreme condition of isospin such as in neutron stars. The present work studies isoscaling using 1) classical molecular dynamics simulations, 2) percolation and 3) probabilistic arguments, and determines that isoscaling is a general phenomenon that can exist independent of the nuclear reaction, and it is expected to occur in disassemblying systems with no more than fair sampling. In collaboration with Alan Davila, University of Texas at Austin; Claudio Dorso, Universidad de Buenos Aires; Carlos Hernandez, Universidad de Colima; Christian Escudero, University of Texas at El Paso; and Jorge Muñoz, CalTech.

  15. Margherita Maria Di Nino, I Fiori campestri di Posidippo. Ricerche sulla lingua e lo stile di Posidippo di Pella

    Directory of Open Access Journals (Sweden)

    Yannick Durbec

    2012-07-01

    Full Text Available L’édition du papyrus P. Mil. Vogl. VIII 309 par Guido Bastianini et Claudio Gallazzi fut pour les spécialistes de l’Antiquité un événement majeur. Les centaines de publications qui s’ensuivirent ont ouvert de multiples pistes de réflexion, préparant la voie pour des travaux de synthèse. Le présent ouvrage de Margherita Maria Di Nino, qui est le fruit de la réélaboration de sa thèse soutenue à l’université de Bologne, est plus que cela. En effet, ce volume o...

  16. 听乐

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    <正>钢琴贵族实至名归Claudio Arrau美国Uhiversal与钢琴名牌Stein- way & Sons出版5件双CD.5位都是Steinway artists(即接受该厂赞助的著名钢琴家)。智利出生.受德国学派教育,老师是李斯特学生Martin Krause的Arrau的一款,很值得推荐。他弹的贝多芬与李斯特,布局雄奇,音响灿烂,扣人心弦。有他在1952年录制的《英雄变奏曲》,是首次在CD上发行(原DG录

  17. La Política Municipal de los Flavios en Hispània. El Municipium Irnitanum

    OpenAIRE

    Muñiz Coello, Joaquín

    1984-01-01

    La Hispània del 68 d. C. sólo haba sufrido superficialmente los efectos del caos en que los últimos años de Nerón habían sumido al gobierno de Roma. Los excesos cometidos en la ciudad por el último de los Julio-Claudios, en materia de gasto y despilfarro público, apenas fueron significativos en Hispània, más por la dejación1 que este emperador hizo de sus funciones de gobernante de un imperio, que por deseo expreso de preservar de la ruina a sus subditos de Occidente. En definitiva, ¡por una ...

  18. “Gaucho primero, después hombre, después negro”. Identidad y relaciones en la pieza teatral El gaucho negro

    Directory of Open Access Journals (Sweden)

    Matías Emiliano Casas

    2014-11-01

    Full Text Available The semantic of the word "gaucho" has been attributed with many meanings in different fields of study and artistic productions. The word's new signification and etymology and the gaucho participation in the economic development of Argentina, among other questions, have been the subject of dispute since the first studies about Independence until today. The play The Gaucho Black of Claudio Martínez Payva, premiered in 1927 at the National Theatre in Buenos Aires, revealed a series of problems, such as: the link with foreign settlers, the construction of identity through the gaucho figure and the relationship with black people. This study provides new tools to analyze the Rioplatense society and culture in the early Twentieth Century.

  19. Slow Travel: in viaggio con l’asino

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    Silvia Mantovani

    2015-11-01

    Full Text Available In viaggio con l’asino (A journey with a donkey is a travel book written by Andrea Bocconi e Claudio Visentin, which describes the adventures of hu- mans and animals along an ancient path in the heart of Abruzzo, as well as recalling the legendary travels with a donkey in the Cévennes don by Robert Louis Stevenson, providing useful informa- tions - practical and philosophical suggestions to manage donkeys – but above all promoting re- marks about travelling, territories, identities and landscapes. This is an interesting lesson, wich in- vites to reflect on different readings: behind a simple travel book, that fascinates, amuses and in- trigues, there are many important ideas that emerge in the watermark. They concern some of the most pressing issues about landscape. 

  20. Ultrasound surveillance in endoluminal laser treatment for varicose veins

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    Varetto G

    2013-10-01

    Full Text Available Gianfranco Varetto, Paolo Garneri, Claudio Castagno, Valentina Molinaro, Simone Quaglino, Matteo Ripepi, Emilio Benintende, Lorenzo Gibello, Stefano Zan, Luigi Contessa, Ugo Bertoldo, Pietro Rispoli Vascular Surgery, Department of Surgical Sciences, University of Turin, Turin, Italy Abstract: Venous ultrasonography is an indispensable tool in minimally invasive surgery for the treatment of varicose veins. However, the criteria for defining preoperative imaging parameters, outcome monitoring, and follow up are not well characterized. In this retrospective study, we reviewed the ultrasound periprocedural parameters and the outcomes in 274 patients (280 limbs after endoluminal laser treatment, at early (<30 days and late (1–60 months follow up. Treatment failure was defined as complete recanalization of the saphenous trunk, thigh perforator vein insufficiency, and recanalization of the proximal saphenous trunk. Judicious patient selection correlated with favorable outcome at the follow-up ultrasound examination. Keywords: follow-up, chronic venous disease, intravenous, obliteration

  1. At the Foot of the Volcano - Organ and Counterpoint in Naples around 1600

    Directory of Open Access Journals (Sweden)

    Ring, Johannes

    2006-12-01

    Full Text Available In 1575, Rocco Rodio published a “Fantasia” on the hymnus “Ave maris stella” in Naples in his Libro di ricercate. In the context of the progressive contributions to music for keyboard instruments of his contemporaries Antonio Valente (1575, Claudio Merulo and Andrea Gabrieli, Rodio’s setting of cantus firmus seems nothing short of anachronistic. But Rodio’s intention lies in the implementation of counterpoint. For him, the art of counterpoint was the decisive basis of the composer’s craft. Rodio’s intention is illuminated by the circumstances of his creative activity –the academies in Naples, always eager to dispute,– and by certain events in Rome and Palermo that culminated in the appearance of the Spaniard named Sebastián Raval. The original context regarding the history of music for Rodio’s “Ave maris stella” is in the liturgical organ music by Antonio de Cabezón, Manuel Rodriguez Coelho und Jean Titelouze und perhaps by António Carreira.

    1575 veröffentlichte Rocco Rodio in Neapel in seinem Libro di ricercate eine Fantasia über den Kirchenhymnus “Ave maris stella”. Im Kontext der progressiven Beiträge zur Tastenmusik seiner italienischen Zeitgenossen Antonio Valente (1575, Claudio Merulo und Andrea Gabrieli erscheint Rodios Cantus firmus-Satz geradezu anachronistisch. Doch Rodios Intention ist die des Kontrapunktikers. Für ihn war die kontrapunktische Kunst die entscheidende Basis des kompositorischen Handwerkes. Rodios Intention wird beleuchtet durch das Umfeld seines Wirkens –den diskussionsfreudigen Akademien in Neapel– und durch Ereignisse in Rom und Palermo, die im Auftritt des Spaniers Sebastián Raval gipfeln. Ihren eigentlichen musikhistorischen Kontext findet Rodios „Ave maris stella“ in der (liturgischen Orgelmusik von Antonio de Cabezón, Manuel Rodriguez Coelho und Jean Titelouze und vielleicht sogar von António Carreira.

  2. IMPARARE L’ITALIANO L2 CON LE CANZONI. UN CONTRIBUTO DIDATTICO

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    Elisabetta Mauroni

    2011-07-01

    Full Text Available Il presente contributo si inserisce nel filone degli studi che hanno messo in evidenza la potenziale ricchezza della canzone come strumento di facilitazione dell’apprendimento della L2, e come mezzo per l’approccio al testo letterario per studenti di italiano L1, additandone il carattere di attività particolarmente efficace e ‘consonante’ con una prospettiva umanistico-affettiva, comunicativa, nonché socio-costruttivista. In queste pagine sono presentate alcune attività didattiche (pensate ora per gli apprendenti di italiano L2, ora per gli studenti di italiano L1 formulate a partire da alcuni testi del cantautore Claudio Baglioni (Io sono qui, Le vie dei Colori, Bolero, Fammi andar via tratti dall’album Io sono qui, 1995, edizioni CBS. I testi qui didattizzati sono utilizzabili in diverse prospettive: grammaticale, lessicale, retorica, socio-culturale, ecc.; e per diversi livelli di competenza linguistica (L2: A1-C1; L1.     Learning italian l2 through song.  A didactic contribution   This article is part of a series of studies which focus on the potential richness of songs as tools for facilitating L2 learning, as well as being a way to approach literary texts for L1 Italian students, being a particularly effective activity from a humanistic-affective, communicative and socio-constructivist point of view.  A few didactic activities are presented (designed for L2 Italian learners, or for L1 Italian learners based on songs by Claudio Baglioni (Io sono qui, Le vie dei Colori, Bolero, Fammi andar via from the album Io sono qui, 1995, edizioni CBS.  The texts were adapted for diverse didactic uses: grammatical, lexical, rhetorical, socio-cultural, etc and for different levels of linguistic competence (L2: A1-C1, L1

  3. Is the Dissociative Experiences Scale able to identify detachment and compartmentalization symptoms? Factor structure of the Dissociative Experiences Scale in a large sample of psychiatric and nonpsychiatric subjects

    Directory of Open Access Journals (Sweden)

    Mazzotti E

    2016-06-01

    Full Text Available Eva Mazzotti,1 Benedetto Farina,2 Claudio Imperatori,2 Federica Mansutti,3,4 Elena Prunetti,3,4 Anna Maria Speranza,5 Claudio Barbaranelli1 1Department of Psychology, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy; 2Department of Human Sciences, European University of Rome, Rome, Italy; 3Associazione di Psicologia Cognitiva e Scuola di Psicoterapia Cognitiva, Rome, Italy; 4Casa di Cura Villa Margherita, Arcugagno (Vi Italy, 5Department of Dynamic and Clinical Psychology, Sapienza University, Rome, Italy Background: In this study, we explored the ability of the Dissociative Experiences Scale (DES to catch detachment and compartmentalization symptoms.Participants and methods: The DES factor structure was evaluated in 768 psychiatric patients (546 women and 222 men and in 2,403 subjects enrolled in nonpsychiatric settings (1,857 women and 546 men. All participants were administered the Italian version of DES. Twenty senior psychiatric experts in the treatment of dissociative symptoms independently assessed the DES items and categorized each of them as follows: “C” for compartmentalization, “D” for detachment, and “NC” for noncongruence with either C or D.Results: Confirmatory factor analysis supported the three-factor structure of DES in both clinical and nonclinical samples and its invariance across the two groups. Moreover, factor analyses results overlapped with those from the expert classification procedure.Conclusion: Our results showed that DES can be used as a valid instrument for clinicians to assess the frequency of different types of dissociative experiences including detachment and compartmentalization. Keywords: Dissociative Experiences Scale, confirmatory factor analysis, detachment, compartmentalization, validity

  4. Dos traducciones costarricenses de Guy de Maupassant

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    Alejandro Alvarado Quirós

    2016-09-01

    Full Text Available La historia de la traducción literaria en Costa Rica ya tiene buena documentación académica que corrobora su desarrollo y su persistencia. Desde los años tempranos del siglo xx, no pocos escritores dedicaron su pluma, a modo de oficio paralelo, tanto a su creación literaria como a la traducción. Sin duda alguna, porque las obras que tradujeron significaban, en buena medida, sus verdaderos modelos de escritura, pero también porque como traductores, entendieron desde temprano que misión suya era también verter al español, y para Costa Rica, obras que de otro modo difícilmente se conocerían con prontitud en el medio. Un insigne escritor costarricense de aquella etapa inicial de las letras nacionales fue Alejandro Alvarado Quirós (1876-1945, autor de crónicas, crítica literaria y ensayos de singular interés. Como escritor asociado al modernismo costarricense, fue asiduo lector de las letras francesas de la segunda mitad del siglo xix, y varios de los grandes narradores del realismo y el simbolismo francés fueron sus preferidos. En 1912 reunió en el pequeño tomo titulado Lilas y resedas (Imprenta Alcina, San José varios cuentos franceses, especialmente del ilustre cuentista Guy de Maupassant. De esa colección se han extraído dos, para esta sección de Letras: «Nuestras cartas» y «Adiós», que pulcramente Alvarado Quirós vertió al español; desde luego, un español culto, al modo del discurso modernista, como conscientemente el traductor ejecutó su labor. Como Alvarado Quirós, no pocos modernistas se vieron seducidos por el oficio de traducir: Roberto Brenes Mesén, Ricardo Fernández Guardia, Fabio Baudrit, José Fabio Garnier. Fue una empresa que se fue convirtiendo en tarea obligada y, con el tiempo, en una especie de tradición solapada, que hasta nuestros días se extiende.

  5. Evaluadores de artículos Caldasia Vol. 16 Nros. 76-79

    Directory of Open Access Journals (Sweden)

    Revista Caldasia

    1991-12-01

    Full Text Available Acero, Arturo / Acosta Alfredo / Aguirre, C. Jaime / Álvarez, Humberto / Andrade, Gonzalo / Arévalo, Isabel / Barrera, Eduardo / Barriga, Ernesto / Bernal, Amanda / Bernal, Rodrigo / Bulla, / M. Germán / Cadena, Albert  / Cala, Plutarco / Campos Martha / Cogollo, Álvaro / Cuadros, Tomas Chamorro, Clara / Churchill, Steven Díaz, Santiago / Duarte, Martha / Dueñas;Hernando / Duque, Santiago / Fernandez, Jose L. / Forero, Eduardo / Franco, Esperanza / Franco, Pilar / Fuertes, Javier / Galeano, Gloria / Galvis, Germán / Gaviria, Elizabeth / Gaviria, Santiago / Gómez, Marcela / González, Favio  / Hernández, C. Jorge / Idrobo, Jesús / La Marca, Enrique / Linares, Mauricio / Londoño, Concha / Lynch,John / Lozano, Gustavo / Lozano, Nubia / Mora, O. Luis E. / Muñoz, Paulina / Murillo, María T. / Orozco, Clara I. / Palacio, Pablo / Pineda, Fabio / Pinto, N. María / Rangel, Orlando / Restrepo, Rubén / Reyes, Carmen / Rueda, Vicente / Ruiz, Pedro M. / Samper, Cristian / Smith, Ernesto / Stiles, Gary / Tchecliakova, Nadya / Turbay, Luisa F. / Uribe, Jaime / Zenner, Ingerborg / Zuluaga,  Silvio

  6. Pilot study of oral administration of a curcumin-phospholipid formulation for treatment of central serous chorioretinopathy

    Directory of Open Access Journals (Sweden)

    Mazzolani F

    2012-05-01

    Full Text Available Fabio MazzolaniPrivate Practice, Milan, ItalyBackground: The purpose of this open-label study was to investigate the effect of a curcumin-phospholipid (lecithin, Meriva® formulation (Norflo® tablet on visual acuity and retinal thickness in patients with acute or chronic central serous chorioretinopathy.Methods: Visual acuity was assessed by ophthalmologic evaluation, and optical coherence tomography was used to measure retinal thickness. Norflo tablets were administered twice a day to patients affected by central serous chorioretinopathy. The study included 18 eyes from 12 patients who completed a 6-month follow-up period. Visual acuity before and after Norflo treatment was the primary endpoint. The secondary endpoints were neuroretinal or pigment epithelial detachment, as measured by optical coherence tomography.Results: After 6 months of therapy, 0% of eyes showed reduction in visual acuity, 39% showed stabilization, and 61% showed improvement. The improvement was statistically significant (P = 0.08. After 6 months of therapy, 78% of eyes showed reduction of neuroretinal or retinal pigment epithelium detachment, 11% showed stabilization, and 11% showed an increase.Conclusion: Our results, albeit preliminary, show that curcumin administered as Norflo tablets is efficacious for the management of central serous chorioretinopathy, a relapsing eye disease, and suggest that bioavailable curcumin is worth considering as a therapeutic agent for the management of inflammatory and degenerative eye conditions, including those that activate the retinal microglia.Keywords: curcumin, central serous chorioretinopathy, retinal pigment epithelium detachment, Norflo®, Meriva®

  7. ALICE presents its first award to Industry

    CERN Multimedia

    On 19 June, a French company received the first ALICE award to industry. ST Technologies has provided ALICE with a key device for the design of a very sophisticated chip for the readout of the ALICE Time Projection Chamber. Behind from left to right (Derrière de gauche à droite): Bernardo Mota, member of the ALTRO design team, Jurgen Schukraft, ALICE Spokesperson, Luciano Musa, leader of the ALTRO Design Team and Coordinator of the ALICE TPC FEE, Roberto Camapagnolo, member of the ALICE TPC FEE team, Jean-Pierre Coffin, Deputy of the ALICE Collaboration Board Chairman, Hans de Groot ALICE Resource Coordinator, Laurent Degoujon, ST - Data Converter Design Manager, Claude Engster, member of the ALICE TPC FEE team, Alain Delpi, ST - Data Converter Business Unit Manager, Carmen Gonzalez, member of the ALICE TPC FEE team, Yiota Foka, ALICE Outreach Coordinator; Front: Fabio Formenti , EP-ED Group Leader, Juan Antonio Rubio, ETT Division Leader The ALICE experiment is setting new demands on readout electronics i...

  8. Modifiable Coronary Heart Disease Risk Factors in the Population Aged 20-49 Years

    Directory of Open Access Journals (Sweden)

    Francisco Carlos Valladares Mas

    2014-04-01

    Full Text Available Background: evidence provided by the Framingham Heart Study established the critical role of risk factors in the development of coronary heart disease. Over half a century later, current detection and control are still inadequate. Objective: to identify modifiable risk factors of coronary heart disease in individuals aged 20 to 49 years. Methods: a descriptive, cross-sectional study was conducted in 276 individuals from the doctor’s office No. 1 of the Fabio di Celmo Community Teaching Polyclinic in Cienfuegos. Patients were examined in the clinic visit and/or whole family visit. The studied variables included age, sex, skin color, risk factors (excess weight/obesity, physical inactivity, smoking, hypertension, diabetes, dyslipidemia and psychosocial factors, which were obtained from the medical interview, physical examination, laboratory tests (total cholesterol and triglycerides and review of individual medical records and family history. Results: risk factors most frequently identified were excess weight/obesity (42.4 %, physical inactivity (34.4 % and smoking (20.3 %. Presence of these risk factors increased with age, showing differences in the distribution by sex and was associated with psychosocial factors. Their coexistence and progress with age was significant. Conclusion: prevalence of modifiable risk factors for coronary heart disease in a young population was high, with frequent association, predominating factors related to unhealthy lifestyles.

  9. 视点

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    趣味设计1 LISBOA落地钟(roche bobois)设计师carlo zerbaro将落地钟的支架设计为可以伸缩的形式,高度可任意调整;钟表的外框可以有金、银、铜三种材质可供选择。2 DIVINA人形沙发(driade)设计师Fabio Novembre设计的人形沙发。3青蛙水壶(POTATO&CO)充满童趣的设计,拉近了童话故事与成年人之间的距离。4 FOLD台灯(Established&SONS)由Alexander Taylor设计,采用了一整张附着了铝涂层的薄板弯折而成,有4种颜色可供选择。5 Little Garden小茶几(Moroso)由Tokujin Yoshioka设计,可以用在室外也可放在室内使用。

  10. Neuroprotective compounds and innovative therapeutic strategies for Parkinson’s disease: experimental and clinical studies

    Directory of Open Access Journals (Sweden)

    Fabio Blandini

    2009-09-01

    Full Text Available Fabio BlandiniInterdepartmental Research Center for Parkinson’s Disease (CRIMP, IRCCS Neurological Institute “C. Mondino Foundation”, Pavia, ItalyAbstract: Identifying new therapeutic strategies capable of modifying the course of Parkinson’s disease (PD is currently one of the major goals for the researchers of this field. Various mechanistic definitions have been proposed to describe the hypothetical ability of a therapeutic intervention to prevent, block or reverse the neurodegenerative process underlying PD. The general term “neuroprotection” has been related to the capacity of interfering with the ongoing process of neuronal cell death, in order to slow or halt disease progression, while a term such as “neurorestoration” would apply to any intervention capable of increasing the number of surviving dopaminergic neurons. Although none of the therapeutic approaches tested in PD patients has so far shown the ability to stop or reverse disease progression, a certain degree of neuroprotection can be achieved with compounds that are already available in the pharmacological armamentarium of the neurologist. Treatment with dopamine agonists or MAO-B inhibitors, particularly when started in the very early phases of the disease, may play disease-modifying effects and even L-DOPA, at low doses, may be slightly neuroprotective. For a true neurorestorative intervention, promising perspectives are being provided by neurotrophic factors and stem cells, which, however, still need to unveil their full potential.Keywords: L-DOPA, dopamine agonists, MAO-B inhibitors, trophic factors, stem cells

  11. Simulation, realization and test of veto systems for the NA62 experiment

    CERN Document Server

    Palladino, Vito

    Search Simple Search Advanced Search Latest Additions Browse Browse by Author Browse by Subject Browse by Year Browse by Type Browse by Full text availability Info Policy About FAQ Contact us Palladino, Vito (2010) Simulation, realization and test of veto systems for the NA62 experiment. [Tesi di dottorato] (Unpublished) [img] PDF palladino_vito_23.pdf Download (55MB) | Preview Item Type: Tesi di dottorato Language: English Title: Simulation, realization and test of veto systems for the NA62 experiment Creators: Creators\tEmail Palladino, Vito\tvitopalladino@gmail.com Date: 30 November 2010 Number of Pages: 146 Institution: Università degli Studi di Napoli Federico II Department: Scienze fisiche Doctoral School: Scienze fisiche PHD name: Fisica fondamentale ed applicata PHD cycle: 23 PHD Coordinator: name\temail Marrucci, Lorenzo\tUNSPECIFIED Tutor: name\temail Ambrosino, Fabio\tUNSPECIFIED Date: 30 November 2010 Number of Pages: 146 Uncontrolled Keywords: Kaon NA62 Veto CHANTI LAV MIUR S.S.D...

  12. The epidemiology of premature aging and associated comorbidities

    Directory of Open Access Journals (Sweden)

    Coppedè F

    2013-08-01

    Full Text Available Fabio Coppedè Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy Abstract: Hutchinson–Gilford Progeria Syndrome and Werner syndrome, also known as childhood- and adulthood-progeria, respectively, represent two of the best characterized human progeroid diseases with clinical features mimicking physiological aging at an early age. The discovery of their genetic basis has led to the identification of several gene mutations leading to a spectrum of progeroid phenotypes ranging from moderate and mild–severe to very aggressive forms. In parallel, the creation of disease registers and databases provided available data for the design of relatively large-scale epidemiological studies, thereby allowing a better understanding of the nature and frequency of the premature aging-associated signs and symptoms. The aim of this article is to review the most recent findings concerning the epidemiology of premature aging disorders, their genetic basis, and the most recent reports on the frequency of associated diseases. Keywords: Hutchinson–Gilford Progeria Syndrome, Werner syndrome, premature aging disorders, epidemiology, cardiovascular diseases, cancer, atherosclerosis, genetics, sign and symptoms

  13. Phaseout of nuclear energy in 2011. The 13th amendment to the Atomic Energy Law from the viewpoint of German constitutional law; Kernenergieausstieg 2011. Die 13. AtG-Novelle aus verfassungsrechtlicher Sicht

    Energy Technology Data Exchange (ETDEWEB)

    Di Fabio, Udo; Durner, Wolfgang; Wagner, Gerhard

    2013-07-01

    The present study analyses the framework provided by German constitutional law in regard to the nuclear energy phaseout in 2011, proceeding in three steps. The contribution by Udo di Fabio is dedicated to the question whether this decision, as well as the manner of its implementation, are in accord with the guarantee of ownership provided by Art. 14 of the German Basic Law (GG). Wolfgang Durner discusses implications of the principle of equality as set out in Art. 3 Section 1 GG in the field of nuclear law. The article by Gerhard Wagner departs from the premise that the restrictions on the use of nuclear power plants should not have been imposed without granting the operators due compensation. These findings are used a basis for determining the implications of fundamental rights for a compensation regime that is in accord with the German constitution. All three contributions originate from a legal expertise that was prepared by the three authors on behalf of the RWE stock company.

  14. Real-time tests of multiple genome alterations take the first steps into the clinic: a learning example

    Directory of Open Access Journals (Sweden)

    Gerratana L

    2016-08-01

    Full Text Available Lorenzo Gerratana,1,2 Giovanna De Maglio,3 Alessandro De Pellegrin,3 Alessandro Follador,1 Karim Rihawi,1,2 Stefano Pizzolitto,3 Fabio Puglisi,1,2 Gianpiero Fasola1 1Department of Oncology, University Hospital of Udine, 2Department of Medical and Biological Sciences, University of Udine, 3Department of Pathology, University Hospital of Udine, Udine, Italy Abstract: Molecular characterization is increasingly changing clinical practice, in both diagnosis and treatment. BRAF is a proto-oncogene that is mutated in ~2%–4% of lung cancers, but the incidence rises to 40%–45% among papillary thyroid cancers. Furthermore, BRAF is a promising target in lung cancer treatment. The present case study covers both the challenges of molecular differential diagnosis and the perspectives opened by targeted therapy by discussing the history of a 78-year-old female affected by a papillary histotype carcinoma with BRAF mutation associated with both thyroid and lung localizations. A differential diagnosis was possible as a consequence of a multidisciplinary approach including an in-depth molecular characterization. Based on this molecular feature, the patient was successfully treated with the BRAF inhibitor dabrafenib after the failure of treatment with standard regimen. To the best of our knowledge, this is the first published case of non-small-cell lung cancer with metastasis to thyroid and with BRAF V600E mutation. Keywords: BRAF mutation, molecular diagnosis, target therapy

  15. Comprehensive cognitive and cerebral hemodynamic evaluation after cranioplasty

    Directory of Open Access Journals (Sweden)

    Coelho F

    2014-05-01

    Full Text Available Fernanda Coelho,1 Arthur Maynart Oliveira,2 Wellingson Silva Paiva,2 Fabio Rios Freire,1 Vanessa Tome Calado,1 Robson Luis Amorim,2 Iuri Santana Neville,2 Almir Ferreira de Andrade,2 Edson Bor-Seng-Shu,3 Renato Anghinah,1 Manoel Jacobsen Teixeira21Neurorehabilitation Group, Division of Neurology, 2Division of Neurosurgery, 3Neurosonology and Cerebral Hemodynamics Group, University of São Paulo Medical School, São Paulo, BrazilAbstract: Decompressive craniectomy is an established procedure to lower intracranial pressure and can save patients' lives. However, this procedure is associated with delayed cognitive decline and cerebral hemodynamics complications. Studies show the benefits of cranioplasty beyond cosmetic aspects, including brain protection, and functional and cerebrovascular aspects, but a detailed description of the concrete changes following this procedure are lacking. In this paper, the authors report a patient with trephine syndrome who underwent cranioplasty; comprehensive cognitive and cerebral hemodynamic evaluations were performed prior to and following the cranioplasty. The discussion was based on a critical literature review.Keywords: cranioplasty, decompressive craniotomy, perfusion CT, traumatic brain injury, cognition, neuropsychological test

  16. Prognostic stratification of acute pulmonary embolism: Focus on clinical aspects, imaging, and biomarkers

    Directory of Open Access Journals (Sweden)

    Luca Masotti

    2009-07-01

    Full Text Available Luca Masotti1, Marc Righini2, Nicolas Vuilleumier3, Fabio Antonelli4, Giancarlo Landini5, Roberto Cappelli6, Patrick Ray71Internal Medicine, 4Clinical Chemistry, Cecina Hospital, Cecina, Italy; 2Division of Angiology and Haemostasis, Department of Internal Medicine, Geneva University Hospital, Switzerland; 3Division of Laboratory Medicine, Department of Genetics and Laboratory Medicine, Geneva University Hospitals and University of Geneva, Switzerland; 5Internal Medicine, Santa Maria Nuova Hospital, Florence, Italy; 6Thrombosis Center, University of Siena, Siena, Italy; 7Department of Emergency Medicine, Centre Hospitalo-Universitaire Pitié-Salpêtrière, UPMC Paris 6, Paris, FranceAbstract: Pulmonary embolism (PE represents a common disease in emergency medicine and guidelines for diagnosis and treatment have had wide diffusion. However, PE morbidity and mortality remain high, especially when associated to hemodynamic instability or right ventricular dysfunction. Prognostic stratification to identify high risk patients needing to receive more aggressive pharmacological and closer monitoring is of utmost importance. Modern guidelines for management of acute PE are based on risk stratification using either clinical, radiological, or laboratory findings. This article reviews the modern treatment of acute PE, which is customized upon patient prognosis. Accordingly the current risk stratification tools described in the literature such as clinical scores, echocardiography, helical computer tomography, and biomarkers will be reviewed.Keywords: pulmonary embolism, prognosis, troponin, BNP, NT-proBNP, echocardiography, computer tomography

  17. SERS-based nanobiosensing for ultrasensitive detection of the p53 tumor suppressor

    Directory of Open Access Journals (Sweden)

    Domenici F

    2011-09-01

    Full Text Available Fabio Domenici, Anna Rita Bizzarri, Salvatore Cannistraro Biophysics and Nanoscience Centre, Faculty of Science, Università della Tuscia, Viterbo, Italy Background: One of the main challenges in biomedicine is improvement of detection sensitivity to achieve tumor marker recognition at a very low concentration when the disease is not significantly advanced. A pivotal role in cancer defense is played by the p53 tumor suppressor, therefore its detection with high sensitivity may contribute considerably to early diagnosis of cancer. In this work, we present a new analytical method based on surface-enhanced Raman spectroscopy which could significantly increase the sensitivity of traditional bioaffinity techniques. p53 molecules were anchored to gold nanoparticles by means of the bifunctional linker 4-aminothiophenol (4-ATP. The characteristic vibrational bands of the p53-4-ATP nanoparticle system were then used to identify the p53 molecules when they were captured by a recognition substrate comprising a monolayer of azurin in molecules possessing significant affinity for this tumor suppressor. The Raman signal enhancement achieved by 4-ATP-mediated crosslinking of p53 to 50 nm gold nanoparticles enabled detect of this protein at a concentration down to 5 × 10-13 M. Keywords: surface-enhanced Raman spectroscopy, p53, ultrasensitive detection, atomic force microscopy

  18. Efecto de rastrojos de malezas y herbicidas pre-emergentes en el control de malezas en frijol

    Directory of Open Access Journals (Sweden)

    Franklin Herrera

    2000-01-01

    Full Text Available En la Estación Experimental Fabio Baudrit, Alajuela, Costa Rica de setiembre de 1998 a febrero de 1999, se evaluó el efecto de los rastrojos de Ixophorus unisetus, Digitaria spp., Cynodon dactylon y Rottboellia cochinchinensis sobre: las malezas, la eficacia de los herbicidas pendimetalina, alaclor e imazetapir, y sobre la nodulación por Rhizobium y el crecimiento del frijol. Se encontró que la presencia de rastrojos sobre la superficie del suelo a razón de 4,5 t de materia seca/ha no fue efectiva para reducir el crecimiento de malezas en el cultivo del frijol sembrado en labranza de conservación. La eficacia de los herbicidas pendimetalina, imazetapir y alaclor no fue afectada por la presencia de los rastrojos sobre la superficie del suelo. Los rastrojos de Ixophorus unisetus afectaron negativamente el crecimiento y la producción del frijol, mientras que los rastrojos de Digitaria spp. y Cynodon dactylon tuvieron efectos positivos sobre el cultivo

  19. Looking at our origins

    CERN Multimedia

    Nairucu Arts

    2011-01-01

    Exhibition by Nairucu-Arts, in collaboration with the Anthropology Museum Giuseppe Sergi, Università la Sapienza, Roma, Italy and ECOLINT, Campus des Nations. The exhibition comprises: posters (in English and French) intended for a large audience with text from Prof. Giorgio Manzi, Julia Rizzo, Fabio Di Vincenzo, illustrated with art drawings from Carlo Ranzi, Italy. The exhibition will also present drawings from the students of the Art Classes of Karin Bain and Fabien Bruttin at ECOLINT,Geneva. On 2nd March at 5 p.m. you will be welcomed with a drink before the conference that will be given in English at 6 p.m in the CERN Council Room by Wim De Geest, a retired Professor from KUB (Catholic University of Brussels). Title: There's no language like our language, like no language we know. But how did it evolve? A summary in French will be made available for the public. http://association.web.cern.ch/association/en/OtherActivities/Origins.html

  20. Clinical features, diagnostic challenges, and management strategies in checkpoint inhibitor-related pneumonitis

    Directory of Open Access Journals (Sweden)

    Chuzi S

    2017-06-01

    Full Text Available Sarah Chuzi,1 Fabio Tavora,2 Marcelo Cruz,3 Ricardo Costa,3 Young Kwang Chae,3 Benedito A Carneiro,3 Francis J Giles3 1Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA; 2Argos Laboratory, Messejana Heart and Lung Hospital, Fortaleza, Brazil; 3Developmental Therapeutics Program, Division of Hematology/Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA Abstract: Immune checkpoint inhibitors, including cytotoxic T-lymphocyte antigen 4 (CTLA-4 and programmed cell death-1 (PD-1 inhibitors, represent an effective treatment modality for multiple malignancies. Despite the exciting clinical benefits, checkpoint inhibition is associated with a series of immune-related adverse events (irAEs, many of which can be life-threatening and result in significant treatment delays. Pneumonitis is an adverse event of special interest as it led to treatment-related deaths in early clinical trials. This review summarizes the incidence of pneumonitis during treatment with the different checkpoint inhibitors and discusses the prognostic significance of tumor type. The wide range of clinical, radiographic, and histologic characteristics of checkpoint inhibitor-related pneumonitis is reviewed and followed by guidance on the different management strategies. Keywords: immune checkpoint inhibitors, pneumonitis, anti-PD-1, anti-CTLA-4, immune-related adverse event

  1. Characterization of the Mid Summer Drought in the Central Valley of Costa Rica, Central America

    Science.gov (United States)

    Alfaro, E.

    2013-05-01

    The IAS region is characterized by climate features of unique nature, one of them is the Mid-Summer Drought (MSD) or "veranillo", an atmospheric feature rarely observed in other tropical regions. On the Pacific slope of Central America, the precipitation annual cycle is characterized by two rainfall maxima in June and September-October, an extended dry season from November to May, and a secondary precipitation minima during July-August (MSD). Three daily gauge stations records, e.g. La Argentina, Fabio Baudrit and Juan Santamaria, located in the Central Valley of Costa Rica were studied to characterize the MSD from 1937 to 2010. Among the aspects considered are the MSD duration, intensity, timing and seasonal predictability. The modulation of these aspects by climate variability sources as Equatorial Eastern Pacific and Tropical North Atlantic was lately explored, including their interannual and decadal variability. The MSD signal strongly impact social and economic life in the region like energy and the agriculture sector. Additionally, the Central Valley of Costa Rica hosts most of the Costa Rican population with the higher level of exposure and vulnerability to hydro-meteorological hazards.

  2. Medicinal clays improve the endurance of loaded inspiratory muscles in COPD: a randomized clinical trial of nonpharmacological treatment

    Directory of Open Access Journals (Sweden)

    Baldi S

    2015-10-01

    Full Text Available Simonetta Baldi,1 Gian Domenico Pinna,2 Claudio Bruschi,1 Fabrizio Caldara,3 Roberto Maestri,2 Elena Dacosto,1 Antonella Rezzani,1 Ermanno Popovich,1 Ezio Bellinzona,1 Paola Crotti,1 Silvia Montemartini,1 Claudio Fracchia1 1Department of Pneumology, 2Department of Biomedical Engineering, Scientific Institute of Montescano, Salvatore Maugeri Foundation, Istituto Di Ricovero e Cura a Carattere Scientifico, Montescano (Pavia, 3Center of Thermal Studies Pietro d’Abano, AbanoTerme, Padua, Italy Background: Inspiratory resistive breathing (IRB challenges affect respiratory muscle endurance in healthy individuals, which is considered to be an interleukin 6 (IL-6–dependent mechanism. Whether nonpharmacological thermal therapies promote the endurance of loaded inspiratory muscles in chronic obstructive pulmonary disease (COPD is unclear. The objectives of this study were to compare the effects of two thermal interventions on endurance time (ET and plasma IL-6 concentration following an IRB challenge.Methods: This study was a randomized, parallel-group, unblinded clinical trial in a single-center setting. Forty-two patients (aged 42–76 years suffering from mild to severe COPD participated in this study. Both groups completed 12 sessions of the mud bath therapy (MBT (n=22 or leisure thermal activity (LTA (n=19 in a thermal spa center in Italy. Pre- and postintervention spirometry, maximum inspiratory pressure, and plasma mediators were obtained and ET and endurance oxygen expenditure (VO2Endur were measured following IRB challenge at 40% of maximum inspiratory pressure.Results: There was no difference in ΔIL-6 between the intervention groups. But, IRB challenge increased cytokine IL-6 plasma levels systematically. The effect size was small. A statistically significant treatment by IRB challenge effect existed in ET, which significantly increased in the MBT group (P=0.003. In analysis of covariance treatment by IRB challenge analysis with LnVO2

  3. Comercio mediterráneo en el castro de Montealegre (Pontevedra, Galicia. Siglo II a.C. – inicios del s. I d. C.

    Directory of Open Access Journals (Sweden)

    González-Ruibal, Alfredo

    2007-12-01

    Full Text Available The Iron Age hillfort of Montealegre, in the Atlantic coast of Galicia (NW Spain, has yielded an interesting array of Mediterranean imports during the last excavations (2003-2004. These imports span mainly from the mid-2nd c. BC to the early 1st c. AD. The late Punic and early Roman trade in the northwest of Iberia was until now scarcely known, unlike the Julio- Claudian commercial relations. The artefacts that made their way to this end of the world include late Punic (Mañá C2b, Iberian (Pellicer D and Italic (Dressel 1 amphorae, kalathoi from Catalonia, and common ware, among other things. The Julio-Claudian period is also well represented, especially by numerous amphorae (Dressel 2/4, Haltern 70, Dressel 7/11. The variety and quantity of imports from the mid-2nd c. BC onwards proves the strong integration of the Galician coast in the Mediterranean network before the Roman conquest of the area.El castro de Montealegre, en la costa de Galicia, ha proporcionado en recientes excavaciones un interesante conjunto de importaciones mediterráneas, de mediados del siglo II a.C. a inicios del siglo I d.C. principalmente. El comercio tardopúnico y romano preaugusteo en el noroeste ibérico era hasta hace poco escasamente conocido, frente a las relaciones comerciales del período julio-claudio. Los objetos que llegaron a este finis térrea incluyen ánforas tardopúnicas (Mañá C2b, ibéricas (Pellicer D e itálicas (Dressel 1, kalathoi de Cataluña y cerámica común, entre otras cosas. El período julio-claudio está asimismo bien representado por numerosas ánforas, fundamentalmente de la Bética (Dressel 2/4, Haltern 70, Dressel 7/11. La variedad y cantidad de importaciones desde mediados del siglo II a.C. en adelante demuestra la gran integración de la costa galaica en las redes mediterráneas desde antes de la conquista romana.

  4. Cost-effectiveness analysis on the use of rFSH + rLH for the treatment of anovulation in hypogonadotropic hypogonadal women

    Directory of Open Access Journals (Sweden)

    Papaleo E

    2014-06-01

    Full Text Available Enrico Papaleo,1 Carlo Alviggi,2 Giorgio Lorenzo Colombo,3,4 Claudio Pisanelli,5,6 Claudio Ripellino,7 Salvatore Longobardi,8 Pier Luigi Canonico91Centro Scienze della Natalità, Gynecological-Obstetrics Department, San Raffaele Hospital, Vita-Salute San Raffaele, Milan, Italy; 2Department of Neuroscience, Reproductive Sciences and Odontostomatology, University “Federico II” of Naples, Naples, Italy; 3Department of Drug Sciences, University of Pavia, Pavia, Italy; 4SAVE Studi Analisi Valutazioni Economiche, Milan, Italy; 5ACO San Filippo Neri, Rome, Italy; 6Società Italiana Di Farmacia Ospedaliera, Milan, Italy; 7CSD Medical Research Srl, Milan, Italy; 8Medical Department, Merck Serono SpA, Rome, Italy; 9Department of Pharmaceutical Sciences, University of Piemonte Orientale, Novara, Italy Background: Hypogonadotropic hypogonadal women are characterized by ovarian functionality deficiency, caused by low concentrations of follicle-stimulating hormone (FSH and luteinizing hormone (LH. To recover reproduction functionality, recommended therapies for ovarian induction involve injections of FSH and LH medications. Objective: Since important differences exist between recombinant and urinary gonadotropin therapies in terms of efficacy and cost, the objective of this study was to develop a cost-effectiveness model to compare recombinant FSH (rFSH + recombinant LH (rLH and highly purified human menopausal gonadotropin (HP-HMG. Methods: A Markov model was developed, considering three cycles of therapy; probability of pregnancy and miscarriage were considered, and the efficacy was evaluated in terms of pregnancy occurrence. The perspective of the model was that of the Italian Health Service, so only direct cost (drugs, specialist visits, patient examinations, and hospitalizations were included. Results: rFSH + rLH is associated with a higher total cost (€3,453.50 and higher efficacy (0.87 compared with HP-HMG (€2,719.70 and 0.50. rFSH + r

  5. El Jardín Botánico de Madrid y sus relaciones con Francia

    Directory of Open Access Journals (Sweden)

    Peset, José Luis

    1996-06-01

    Full Text Available The Botanical Garden from Madrid was created in 1755 with the purpose of studying and cultivate the medicinal plants. Its ulterior evolution is characterized for its relationship with the Garden of Plants of Paris, circumstance that retarded the application of the Linnean system in favor of the model of Tournefort. With the transfer of the Garden, in 1774, to its actual location of the Paseo del Prado, the French bond increases. The first professor, Casimiro Gómez Ortega, travels to Paris where he contacts with André Thouin, Duhamel de Monceau, and Buffon, whose botanical guidelines try to introduce at his return. But it will be at the posterior management of Claudio Boutelou, during the reign of José I, when the French presence in the Garden obtains its paramount influence. Influence and collaboration between the two institutions that continues today.

    El madrileño Jardín Botánico fue creado en 1755 con el fin de estudiar y cultivar las plantas medicinales. Su ulterior evolución se caracteriza por su relación con el parisino Jardín de Plantas, circunstancia que retrasó la aplicación del sistema linneano en favor del modelo de Tournefort. Con el traslado en 1774 del Jardín a su actual emplazamiento del Paseo del Prado, el vínculo francés aumenta. El primer catedrático Casimiro Gómez Ortega viaja a París donde contacta con André Thouin, Duhamel de Monceau y Buffon, cuyas directrices botánicas trata de implantar a su regreso. Pero será con la posterior dirección de Claudio Boutelou, durante el reinado de José I, cuando la presencia francesa en el Jardín alcanza su máxima cuota. Influencia y colaboración entre las dos instituciones que llegará hasta hoy.

  6. España y los españoles

    Directory of Open Access Journals (Sweden)

    Caba, Rubén

    2011-10-01

    Full Text Available The author here argues in favour of the historical reality that we call Spain. To recognize the Cadiz Constitution of 1812 as the origin of present Spain, he maintains, does not imply that our country had no national identity before the 19th century. And to this effect he expounds the famous controversy between Americo Castro and Claudio Sánchez-Albornoz. Before the Arab invasion there were no “españoles”, since this word of provençal origin dates back to the 11th century, as Castro points out. However, it is also true that during the Roman as well the Gothic domination, the peninsular inhabitants were known as “hispani”, as Sánchez-Albornoz sarcastically alleges. In addition, this article includes a number of quotations from Latin, Gothic and Spanish writers of the Middle Ages and the Renaissance, references which bear witness to a feeling of belonging to an old country called “Hispania” or “España”.

    El autor aporta argumentos en favor de la realidad histórica que llamamos España. Sostiene que reconocer a la Constitución de Cádiz de 1812 como origen de la España política actual no implica que nuestro país careciera de identidad nacional antes del siglo XIX. Y expone la controversia de Américo Castro y de Claudio Sánchez-Albornoz sobre la génesis histórica de España para concluir que, si bien antes de la invasión árabe no había “españoles”, vocablo provenzal del siglo XI como advierte Castro, también es cierto que durante la dominación romana y goda los peninsulares eran “hispani”, como alega con sorna Sánchez-Albornoz. Además, se recogen citas de autores latinos, godos y españoles tanto medievales como renacentistas que testimonian su sentimiento de pertenecer a un viejo país llamado Hispania o España.

  7. Kikuchi-Fujimoto disease mimicking tuberculous lymphadenitis or lymphoma on fluorine-18 fluorodeoxyglucose positron emission tomography/computed tomography

    Directory of Open Access Journals (Sweden)

    Abdul Rahim N

    2016-07-01

    Full Text Available Noraini Abdul Rahim,1 Abdul Jalil Nordin,2 Chiara Rusconi,3 Cristina Gabutti,3 Erika Ravelli,4 Claudio Rossetti5 1Diagnostic Imaging Department, Serdang Hospital, Selangor, 2Centre for Diagnostic Nuclear Imaging, University Putra Malaysia, Serdang, Malaysia; 3Department of Haematology, Ospedale Niguarda, Milan, 4Unit of Haematology, Valduce Hospital, Como, 5Department of Advance Technology (Nuclear Medicine, Ospedale Niguarda, Milan, Italy Abstract: Kikuchi-Fujimoto disease, also known as histiocytic lymphadenitis is a rare and benign disease characterized by regional cervical lymphadenopathy with fever of unknown origin, affecting mainly young women. We describe a case of a young Asian female who was initially misdiagnosed as having tuberculous lymphadenitis because of multiple lymphadenopathies with 18-fluorodeoxyglucose uptake on positron emission tomography/computed tomography. Final histologic diagnosis of Kikuchi-Fujimoto disease was made after excisional biopsy of the affected lymph node. The cervical lymphadenopathy has reduced in size and lung lesions disappeared after 2 months without specific treatment. Keywords: cervical lymphadenopathy, Kikuchi disease, PET/CT features

  8. REDISCOVERING MISES-HAYEK MONETARY AND BUSINESS CYCLE THEORY IN LIGHT OF THE CURRENT CRISIS: CREDIT EXPANSION AS A SOURCE OF ECONOMIC BOOM AND BUST

    Directory of Open Access Journals (Sweden)

    Marcin Mrowiec

    2013-10-01

    Full Text Available The article starts with a brief description of Mises’ monetary theory, with emphasis on the Misesian differentiation of two kinds of credit: commodity and circulation credit, and with the description of the impact of circulation credit expansion on the business cycle. Further on it is described how Mises’ insights constituted the kernel of Austrian Business Cycle Theory, and how the same observations on the nature of credit constituted the kernel of the Chicago Plan (though Mises’ views on the nature of credit led him to different conculsions than it led the authors of the Chicago Plan, and how this plan is being “rediscovered” now. The following sections deal with observations of one of the preeminent current macroeconomic researches, Mr. Claudio Borio, on the elasticity of credit as the source of the current crisis, and on the importance of the financial cycle in analysing the current economic crisis. The author of this text demonstrates that Austrian Business Cycle Theory gave the same answer regarding the sources of economic crises that now modern macroeconomic theory seems to be approaching, and that the postulates for successful financial cycle modeling are already included in the ABCT. Finally, some observations on the current crisis, as well as proposals of avenues of further research are proposed.

  9. Procedure for obtaining visas for Switzerland and France

    CERN Multimedia

    2006-01-01

    Signature Rights In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization's personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d'accueil. Oliver BRÜNING Philip BRYANT Lyndon EVANS John FERGUSON David JACOBS Catherine JONES Hélène HALLER-MAUGER Michelle MAZERAND Chris ONIONS Claudio PARRINELLO The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), 'the Organization shall not request any legitimisation document (or residence permit) or visa from the Host States for persons registered as EXTERNAL' (p...

  10. Procedure for obtaining visas for Switzerland and France - Signature Rights

    CERN Document Server

    HR Department

    2007-01-01

    In accordance with their Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization's personnel onto their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of these procedures, only the following individuals are authorised to initiate the note verbale procedure, as well as to sign the Official Invitation Letters and the Protocoles d'accueil. Oliver BRÜNING Philip BRYANT Lyndon EVANS John FERGUSON Hélène HALLER-MAUGER David JACOBS Catherine NEDERMAN Chris ONIONS Claudio PARRINELLO Jeanne ROSTANT The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that, in accordance with the memorandum of 7 December 2000 issued by the Director of Administration, (ref. DG/DA/00-119), 'the Organization shall not request any legitimisation document (or residence permit) or visa from the Host States for persons registered as EXTERNAL' (people w...

  11. Procedure for obtaining visas for Switzerland and France

    CERN Multimedia

    2007-01-01

    Signature Rights In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organizations personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles daccueil. Oliver BRÜNING Philip BRYANT Lyndon EVANS John FERGUSON Hélène HALLER-MAUGER David JACOBS Catherine NEDERMAN Chris ONIONS Claudio PARRINELLO Jeanne ROSTANT The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), 'the Organization shall not request any legitimisation document (or residence permit) or visa from the Host States for persons registered as E...

  12. PROCEDURE FOR OBTAINING VISAS FOR SWITZERLAND AND FRANCE

    CERN Multimedia

    2007-01-01

    SIGNATURE RIGHTS In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d’accueil. •\tOliver BRÜNING •\tVinod CHOHAN •\tLyndon EVANS •\tJohn FERGUSON •\tHélène HALLER-MAUGER •\tDavid JACOBS •\tPhilippe LEBRUN •\tCatherine NEDERMAN •\tChris ONIONS •\tClaudio PARRINELLO •\tJeanne ROSTANT The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), "the Organization shall not request any legitimisation d...

  13. Procedure for obtaining visas for Switzerland and France

    CERN Document Server

    Relations with the Host States Service

    2006-01-01

    Signature rights In accordance with their Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization's personnel onto their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of these procedures, only the following individuals are authorised to initiate the note verbale procedure, as well as to sign the Official Invitation Letters and the Protocoles d'accueil. Oliver BRÜNING Philip BRYANT Lyndon EVANS John FERGUSON Catherine JONES Nicolas KOULBERG Hélène HALLER-MAUGER Michelle MAZERAND Chris ONIONS Claudio PARRINELLO The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that, in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration (ref. DG/DA/00-119), 'the Organization shall not request any legitimisation document (or residence permit) or visa from the Host States for persons registered as EXTERNA...

  14. PROCEDURE FOR OBTAINING VISAS FOR SWITZERLAND AND FRANCE

    CERN Multimedia

    2007-01-01

    SIGNATURE RIGHTS In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization’s personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d’accueil. •\tOliver BRÜNING •\tPhilip BRYANT •\tLyndon EVANS •\tJohn FERGUSON •\tHélène HALLER-MAUGER •\tDavid JACOBS •\tPhilippe LEBRUN •\tCatherine NEDERMAN •\tChris ONIONS •\tClaudio PARRINELLO •\tJeanne ROSTANT The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), "the Organization shall not request any legitimisation document (or residence per...

  15. Staging Death, Translating Death, Rehearsing Death: A Photographer’s Apprenticeship in Dying

    Directory of Open Access Journals (Sweden)

    Daniela Fargione

    2010-10-01

    Full Text Available The preponderance of death imagery in the mass media and a recent interest of photography in the practice of death suggest the need to reevaluate our approach to death and dying, especially when violence is involved. This essay is a case study of History of Violence, Claudio Cravero's last photographic project. His collection of "portraits" reproduce apparent dead bodies, mostly attacked in their own domestic spheres, but neither the perpetrator of death (a mysterious murderer?, nor the weapon used (an omnipresent knife, should be considered as main focal points of the artist's inquiry. The undoubtful protagonist of these photographs, instead, is the light, that illuminates fear: not of death itself, rather of the obnoxious indifference to it, as the result of generalized death imagery saturation.     The staged apparent death displayed in Cravero's photographs serve both as a memento mori and as a strategy to come to terms with the idea of death. In short, it is an apprentship in dying through a domesticating translation practice. Eventually, Cravero's History of Violence offers a complex reflection on the interplay between each individual story and macrolevel social History, thus providing some hypotheses of where violence and death fit in that odd geometry of time and space that we call life.

  16. Alfabetización informacional a través de Moodle

    Directory of Open Access Journals (Sweden)

    Gabriela Fernanda Cabrera Rossi

    2015-01-01

    Full Text Available Se describe la experiencia de la Biblioteca “Dr. Claudio Williman” de la Facultad de Educación Física del Instituto Universitario de la Asociación Cristiana de Jóvenes (IUACJ, en el desarrollo de cursos que contribuyen a la mejora de la calidad formal de los trabajos académicos. Se presentan distintos tipos de cursos impartidos por Biblioteca de carácter semipresencial, los cuales generan créditos académicos y son desarrollados bajo la plataforma Moodle. Se describe el proceso de integración del IUACJ a Moodle como herramienta educativa facilitadora para el desarrollo y organización de los cursos. Se analiza la contribución del bibliotecólogo, como gestor de información, evaluando recursos para luego ponerlos a disposición de la comunidad académica de estudiantes, proporcionando acciones que contribuyan a consolidar a la Biblioteca en su rol de alfabetizador, favoreciendo la adquisición de conocimientos y habilidades de los usuarios. También se enumeraran los cursos dictados por la Biblioteca describiendo estructura, metodología aplicada y recursos didácticos.

  17. Staff Members with more than 25 years service at CERN in 2000

    CERN Multimedia

    2000-01-01

    Allegrini Roberto SL Arimatea Claudio SL Baudic Yves SPL Becquet Christian SL Bergamaschi Angelo ST Bourquin Pierre EST Brand Jean-Paul ST Bresciani Pietro EST Brocard Robert EP Cameron Willie EST Carminati Daniel PS Chasseloup De Laubat Jacques ST Chouvelon Alain TIS Cittolin Sergio EP Cochet Evelyne ST Coly Patrick LHC David Eric EP De Jonge Luit Koert SL Delattre André LHC Detraz Claude Charles EP Dreesen Peter PS Dydak Friedrich EP Favini Pierre EST Ferioli Gianfranco SL Fiebiger Heinz PS Fontbonne Andrée HR Fournel Jacques EST Fournier Gérard AS Fromm Daniel EP Gagliardi Fabrizio IT Gaidon Michèle ST Galbraith Peter LHC Gavaggio Richard LHC Genand Roger SL Gendre Francis PS Geoffroy Michel ST Geretschlager Ingrid ETT Grabit Robert EP Grill Manfred ST Heinze Wolfgang PS Hoh Roger PS Hudry Jean SL Jenny Bernard EST Koutchouk Jean-Pierre SL Laffin Michel SL Laurent Jean-Michel LHC Le Gras Marc PS Legrand Patrick LHC Lerho Jean-Marie ST Lewis Ray ETT Liptow Ulr...

  18. “History is not linear … it zigzags”: The Perception of Time in Magris' novel Blindly

    Directory of Open Access Journals (Sweden)

    Irena Prosenc Šegula

    2012-12-01

    Full Text Available In his novel Blindly Claudio Magris develops a complex perception of time. This perception is intertwined with reflections on history, identity and the status of the narrative voice. History, which “is not linear” but “zigzags” is presented as a continuously repetitive phenomenon, while temporal time is impossible to measure. The status of the autodiegetic narrator becomes highly problematic as the narrative voice assumes identities belonging to various historical periods ranging from the late 18th to the 20th centuries. The novel focuses on repressive historical periods which deform the protagonists' identities, thereby conveying an image of history as a blind and violent force. Fragmentation, one of the basic narrative techniques in the novel, concerns time sequences as well as the protagonists' identities and the narrative voice itself. As the protagonists' lives can only be narrated as fragments, there are frequent passages between different time periods. These merge into extratemporality, which is associated with eternal suffering stemming from the repetitive, oppressive nature of history. The historical events depicted in the novel are interpreted through the extratemporal dimension of the Argonaut myth.

  19. Aproximación a la enseñanza secundaria durante el Franquismo (1938-1967

    Directory of Open Access Journals (Sweden)

    Leoncio VEGA GIL

    2010-03-01

    Full Text Available RESUMEN: El trabajo que abordamos en esta monografía se centra cronológicamente en el ciclo histórico conocido como franquismo y a nivel de contenido delimitamos el estudio a la enseñanza secundaria tanto desde su dimensión formal y política, a partir de los pilares legislativos que sobre este nivel se fueron erigiendo (1938, 1953 y 1967, como desde la realidad escolar en términos cuantitativos de la geografía nacional y un estudio interno más profundo de algunas variables para el caso de su articulación en Zamora. Y, si las fuentes nos lo permiten, entraremos en las cuestiones del «tercer nivel», la mentalidad del alumno de segunda enseñanza y su relación con el modelo social y académico real de los alumnos que asisten a cursar estudios en el Instituto «Claudio Moyano» de Zamora o de los que cursan la enseñanza colegiada, tan potenciada esta última ahora por el régimen.

  20. Importance of perforating vessels in nipple-sparing mastectomy: an anatomical description

    Directory of Open Access Journals (Sweden)

    Amanti C

    2015-07-01

    Full Text Available Claudio Amanti,1 Valeria Vitale,1 Augusto Lombardi,1 Stefano Maggi,1 Laura Bersigotti,1 Gianni Lazzarin,1 Emiliano Nuccetelli,1 Camilla Romano,1 Laura Campanella,1 Lara Cristiano,2 Alessandra Bartoloni,2 Giuseppe Argento2 1Breast Surgery Unit, 2Radiology Unit, University of Roma, La Sapienza Sant'Andrea Hospital, Rome, Italy Background: Nipple-sparing mastectomy (NSM, understood as an oncologically valid procedure, is relatively new, and is an evolution of traditional mastectomy, particularly in relation to breast-conserving surgery. The anterior perforating branches are responsible for the cutaneous vascularization of the breast skin, and their preservation is a fundamental step to avoid possible postoperative necrosis. Therefore, evaluating the potential complications of cancer-related reconstructive surgical procedures such as NSM, both the distance of the tumoral lesion from the skin and the surgical incision site should be carefully considered. The preferred site of incision corresponds to the inframammary fold or possibly the periareolar area.Methods: We retrospectively reviewed 113 patients who underwent NSM from January 2005 to October 2012 to evaluate skin complications. The anatomical study was performed by magnetic resonance imaging of the breast.Results: Only one of the 113 women who had undergone a NSM procedure had total necrosis (0.9% and six patients had partial necrosis (5.8% of the nipple-areola complex. Keywords: nipple-sparing mastectomy, breast, magnetic resonance imaging, breast perforating vessels, breast anatomy

  1. The beginnings of dermatopathology and dermatologic microbiology in Spain.

    Science.gov (United States)

    del Río, E

    2014-03-01

    Crisóstomo Martínez from Valencia was a pioneering microscopist in 17th-century Europe. The first microscopic representations of skin in Spain appeared in an 18th-century work by Martín Martínez. Microbiology and histopathology progressed considerably in the late 19th century thanks to anatomists like Maestre de San Juan and surgeons like Federico Rubio Galí. The first Spanish pathologist to specialize in dermatology was Antonio Mendoza, a colleague of José Eugenio de Olavide at the Hospital San Juan de Dios in Madrid. Claudio Sala and Juan de Azúa also made significant contributions, including the description of pseudoepithelioma. Several disciples of Santiago Ramón y Cajal and Jorge FranciscoTello, such as Lorenzo Ruiz de Arcaute and Guillermo de la Rosa King, consolidated the dermatology laboratory, but the Civil War sent many into exile or deprived them of their professional status. Juan Rubió in Barcelona and Julio Rodríguez Puchol in Madrid were the immediate predecessors of today's dermatopathologists. Copyright © 2012 Elsevier España, S.L. y AEDV. All rights reserved.

  2. Targets, attitudes, and goals of psychiatrists treating patients with schizophrenia: key outcome drivers, role of quality of life, and place of long-acting antipsychotics

    Directory of Open Access Journals (Sweden)

    de Bartolomeis A

    2016-01-01

    Full Text Available Andrea de Bartolomeis,1 Andrea Fagiolini,2 Marco Vaggi,3 Claudio Vampini4 1Section of Psychiatry and Treatment Resistant Psychosis, Department of Neuroscience, University of Naples Federico II, Naples, Italy; 2Department of Molecular and Developmental Medicine, School of Medicine, University of Siena, Siena, Italy; 3Mental Health and Drug Addiction Department, Genovese, Genoa, Italy; 4Department of Mental Health, Ospedale Civile Maggiore and ULSS 20, Verona, Italy Purpose: This survey of Italian psychiatrists was conducted to better define drivers of schizophrenia treatment choice in real-life practice, particularly for use of long-acting injectable (LAI antipsychotics.Methods: Between October 15 and December 15, 2014, 1,000 surveys were sent to psychiatrists who treat schizophrenic patients; 709 completed questionnaires were analyzed (71% response rate.Results: The two most important factors determining therapy success were efficacy (75% of responses and tolerability (45% followed by global functioning (24% and quality of life (17%. LAI antipsychotics were most often used to facilitate regular treatment monitoring (49%, and 41% of psychiatrists thought that patients with low adherence who had failed oral therapy were well-suited for LAI antipsychotics. Only 4% of respondents saw LAI antipsychotics as appropriate for patients without other therapeutic options.Conclusion: Although efficacy and tolerability were the most common factors used to evaluate treatment success in schizophrenia, psychiatrists also consider QoL and global functioning to be important. Keywords: quality of life, long-acting injectable antipsychotics, schizophrenia, survey

  3. Pedro de Castañeda: su pintura para el refectorio del Colegio Mayor de San Ildefonso (1553

    Directory of Open Access Journals (Sweden)

    González Ramos, Roberto

    2003-09-01

    Full Text Available El pintor Pedro de Castañeda es un artista poco conocido, activo en la zona de Alcalá de Henares en las décadas centrales del siglo XVI. Se sabe que junto a su hijo Juan fue colaborador del entallador y traductor de Vitruvio Miguel de Urrea. Pedro de Castañeda pintó un cirial que había tallado Urrea para la iglesia parroquial de Camarma de Esteruelas, trabajo por el que ambos cobraron cierta cantidad en 1540, y en 1550 colaboró con ese entallador y con Claudio de Arciniega, ayudado por Juan, en la obra de los retablos colaterales de la iglesia de Daganzo de Arriba (perdidos, realizando su pintura. Parece que se trata del mismo artista el Pedro Castañeda que se documenta trabajando en la zona de Segovia, concretamente en dos retablos para la iglesia de Cascajares del Fresno. Falleció en 1557…

  4. Cryopreservation of chayote (Sechium edule JACQ. SW.) zygotic embryos and shoot-tips from in vitro plantlets.

    Science.gov (United States)

    Abdelnour-Esquivel, Ana; Engelmann, Florent

    2002-01-01

    This paper presents the development of cryopreservation protocols for zygotic embryos and apices of chayote (Sechium edule Jacq. Sw.), a tropical plant species with recalcitrant seeds. Zygotic embryos of two cultivars, Ccocro negro (CN) and Claudio (Cl) could withstand cryopreservation, with survival percentages of 10 and 30 %, after desiccation to 23 and 19 % moisture content (fresh weight basis), respectively. Apices sampled on in vitro plantlets of cultivars Cl, 13 and JM were successfully cryopreserved using a vitrification technique. Optimal conditions included the culture of mother-plants for 22 days on medium containing 0.3 M sucrose, culture of excised apices on the same medium for 1 day, loading of apices for 20 min with 2M glycerol + 0.4M glycerol, treatment with a series of diluted PVS2 solution (60 % PVS2 followed by 80 % PVS2 solution for 15 min (cultivar Cocoro Blanco [CB]) or 30 min (cultivars CN and Cl) at each concentration), rapid freezing and thawing, washing of shoot-tips with a 1.2 M sucrose solution, followed by recovery on media with progressively decreasing sucrose concentrations until the standard concentration of 0.1 M was reached. The highest survival percentages achieved ranged between 17 and 38 %, depending on the cultivar.

  5. Destiny Transform in the Ethical Confusion and Reconstruction of Ethical Order of Measure for Measure%《一报还一报》的伦理混乱与秩序重构中的悲喜命运转向

    Institute of Scientific and Technical Information of China (English)

    刘玉杰; 黄晓洁

    2014-01-01

    莎士比亚《一报还一报》一剧以克劳狄奥与朱丽叶的婚前私通为主要伦理线,展示了维也纳法治下个人私通和公共淫乱两类人的跌宕命运,着重探讨了维也纳城的伦理混乱,以及在主政者的伦理秩序重构中个人私通者由悲而喜和公共淫乱者由喜而悲的命运转向,旨在指出在西方前现代社会中,对基督教伦理规范的认同与否决定着个人的命运转向。%Claudio and Juliet’ s adultery is the main ethical line of William Shakespeare’ s drama Measure for Measure. The drama demonstrates adulterer and whoremonger’ s destiny transform under Vienna’ s nomocracy. This paper focuses on Vienna’ s ethical con-fusion, adulterer’ s tragic fate transform to comedy fate,while whoremonger’ s comedy fate transform to tragic fate. Aims to point out that , in the pre-modern western society, whether identity for Christian ethics determines the fate of the individual.

  6. Life-threatening asthma attack during prolonged fingolimod treatment: case report

    Directory of Open Access Journals (Sweden)

    Zecca C

    2014-07-01

    Full Text Available Chiara Zecca,1,* Matteo Caporro,1,* Sandor Györik,2 Claudio Gobbi11Neurocenter of Southern Switzerland, Department of Neurology, Ospedale Regionale di Lugano, Lugano, Switzerland; 2Department of Internal Medicine, Ospedale Regionale di Bellinzona, Bellinzona, Switzerland*These authors contributed equally to this workBackground: Fingolimod (FTY mediates bronchoconstriction by interacting with sphingosine-1-phosphate receptors. The majority of the reported adverse respiratory events occur during the first weeks of treatment.Case presentation: A 49-year-old woman developed a life-threatening asthma attack after 6 months of continuous FTY treatment. The adverse event required prolonged hospitalization, and the patient recovered without sequelae after FTY interruption. A history of previous airway hyperreactivity and a concurrent viral respiratory infection possibly acted as predisposing factors.Conclusion: This first description of a severe, life-threatening asthma attack during prolonged FTY treatment suggests the need for long-term clinical surveillance, especially in patients with known predisposing factors.Keywords: multiple sclerosis, bronchial hyper-reactivity

  7. Role of Ocrl1 and Inpp5E in primary cilia assembly and maintenance: a phosphatidylinositol phosphatase relay system?

    Directory of Open Access Journals (Sweden)

    Madhivanan K

    2016-02-01

    Full Text Available Kayalvizhi Madhivanan,* Swetha Ramadesikan,* R Claudio Aguilar Department of Biological Sciences, Purdue University, West Lafayette, IN, USA *These authors contributed equally to this work Abstract: The primary cilium (PC is a plasma membrane-derived structure of great importance for cell and organismal physiology. Indeed, abnormalities in assembly or function of the PC trigger the onset of a group of genetic diseases collectively known as ciliopathies. In recent years, it has become evident that the integrity and function of the PC depends substantially on signaling elements such as phosphoinositides (PI and their regulators. Because phospholipids such as PI(4,5P2 constitute recruitment platforms for cytoskeleton, signaling, and trafficking machinery, control over their levels is critical for PC function. Although information about phosphoinositol phosphate (PIP kinases in the PC is scarce, a growing body of evidence supports a role for PIP phosphatases in cilia assembly/maintenance. Indeed, deficiencies in two 5′ PIP phosphatases, Inpp5E and Ocrl1, are clearly linked to ciliopathies like Joubert/MORM syndromes, or ciliopathy-associated diseases like Lowe syndrome. Here, we review the unique roles of these proteins and their specific site of action for ensuring ciliary integrity. Further, we discuss the possibility that a phosphatase relay system able to pass PI control from a preciliary to an intraciliary compartment is in place to ensure PC integrity/function. Keywords: primary cilia, Ocrl1, Inpp5E, Pip2, Pip3

  8. Procedure for obtaining visas for Switzerland and France

    CERN Multimedia

    2006-01-01

    Signature Rights In accordance with the Status Agreements with CERN, Switzerland and France facilitate the entry of members of the Organization's personnel on to their territories. Where relevant, detailed procedures for obtaining visas apply. Within the framework of those procedures, only the following individuals are authorised to initiate the note verbale procedure as well as to sign the Official Invitation Letters and the Protocoles d'accueil. Oliver BRÜNING Philip BRYANT Lyndon EVANS John FERGUSON David JACOBS Catherine JONES Hélène HALLER-MAUGER Michelle MAZERAND Chris ONIONS Claudio PARRINELLO The French and Swiss Authorities will reject any request signed by a person who is not on this list. We would like to remind you that in accordance with the memorandum of 7 December 2000 issued by the Director of the Administration, (ref. DG/DA/00-119), 'the Organization shall not request any legitimisation document (or residence permit) or visa from the Host States for persons registered as EXTERNAL' (p...

  9. Cine Club

    CERN Document Server

    Cine Club

    2012-01-01

    Thursday 10 January 2013 at 20:00 CERN Council Chamber Viridiana Directed by Luis Buñuel (Spain/Mexico, 1961) With: Silvia Pinal, Fernando Rey, Francisco Rabal Original version spanish; english subtitles; 90 minutes Viridiana, a young novice about to take her final vows as a nun, accedes to a request from her widowed uncle to visit him. Moved purely by a sense of obligation, she does so. Her uncle is moved by her resemblance to his late wife to attempt to seduce Viridiana, and tragedy ensues. In the aftermath, Viridiana tries to assuage her guilt by creating a haven for the destitute folk who live around her uncle’s estate. But from these good intentions, too, comes little good. Simon of the Desert Directed by Luis Buñuel (Spain/Mexico, 1965) With: Silvia Pinal, Claudio Brook, Enrique Alvarez Félix Original version spanish; english subtitles; 45 minutes Simon, a deeply religious man living in the 4th century, wants to be nearer to God so he climbs a c...

  10. Technological process for production of persimmon and strawberry vinegars

    Directory of Open Access Journals (Sweden)

    Claudio Hidalgo

    2010-08-01

    Full Text Available Claudio Hidalgo1, Estibaliz Mateo1, Ana Belen Cerezo2, Maria-Jesús Torija1, Albert Mas11Biotecnologia Enològica, Departament de Bioquimica i Biotecnologia, Facultat d’Enologia, Universitat Rovira i Virgili, Marcel-li Domingo, Tarragona; 2Área de Nutrición y Bromatología, Facultad de Farmacia, Universidad de Sevilla, Sevilla, SpainAbstract: Fruit surplus is common in intensive agriculture in many countries. This ecologic and economic problem requires alternative uses to be found for fruit. The aim of this study was to use surplus fruit to produce vinegar by traditional methods (alcoholic fermentation and acetification from persimmon and strawberry. The process was performed with naturally occurring microorganisms and compared with inoculated commercial wine yeast for alcoholic fermentation. Alcoholic fermentation proceeded faster when inoculated due to the length of the lag phases observed in spontaneous fermentations. The alcoholic fermentations of strawberry mash were faster than those of persimmon mash. In contrast, acetifications were much faster in persimmon (30 days than in strawberry (70 days, in the latter some acetifications were not finished. From the technologic point of view, to produce persimmon and strawberry wine and vinegar, it is better to avoid fruit pressing and perform the process with fruit mash. Inoculation is recommended for persimmon and is necessary for strawberry.Keywords: wine, vinegar, fruit seasonings, acetic acid bacteria

  11. Development of oral agent in the treatment of multiple sclerosis: how the first available oral therapy, Fingolimod will change therapeutic paradigm approach

    Directory of Open Access Journals (Sweden)

    Gasperini C

    2012-07-01

    Full Text Available Claudio Gasperini,1 Serena Ruggieri21Department of Neurosciences, S Camillo Forlanini Hospital, 2Department of Neurology and Psychiatry, University of Rome “Sapienza,” Rome, ItalyAbstract: Multiple sclerosis (MS is a chronic inflammatory disorder of the central nervous system, traditionally considered to be an autoimmune, demyelinating disease. Based on this understanding, the initial therapeutic strategies were directed at immune modulation and inflammation control. At present, there are five licensed first-line disease-modifying drugs and two second-line treatments in MS. Currently available MS therapies have shown significant efficacy throughout many trials, but they produce different side-effect profiles in patients. Since they are well known and safe, they require regular and frequent parenteral administration and are associated with limited long-term treatment adherence. Thus, there is an important need for the development of new therapeutic strategies. Several oral compounds are in late-stage development for treating MS. Fingolimod (FTY720; Novartis, Basel, Switzerland is an oral sphingosine-1-phosphase receptor modulator which has demonstrated superior efficacy compared with placebo and interferon β-1a in Phase III studies and has been approved in the treatment of MS. We summarily review the oral compounds in study, focusing on the recent development, approval and the clinical experience with FTY720.Keywords: multiple sclerosis, oral compounds, fingolimod, fty720, sphingosine 1, phosphate, patient satisfaction

  12. Advances in the treatment of relapsing–remitting multiple sclerosis – critical appraisal of fingolimod

    Directory of Open Access Journals (Sweden)

    Gasperini C

    2013-03-01

    Full Text Available Claudio Gasperini,1 Serena Ruggieri,2 Chiara Rosa Mancinelli,2 Carlo Pozzilli2 1Department of Neurosciences, S Camillo Forlanini Hospital, Rome, Italy; 2Department of Neurology and Psychiatry, Sapienza – University of Rome, Rome, Italy Abstract: Multiple sclerosis (MS is a chronic inflammatory disorder of the central nervous system, traditionally considered to be an autoimmune, demyelinating disease. Based on this understanding, initial therapeutic strategies were directed at immune modulation and inflammation control. At present, there are five licensed first-line disease-modifying drugs for MS in Europe, and two second-line treatments. Currently available MS therapies have shown significant efficacy throughout many trials, but they produce different side effects. Despite disease-modifying drugs being well known and safe, they require regular and frequent parenteral administration and are associated with limited long-term treatment adherence. Therefore, the development of new therapeutic strategies is warranted. Several oral compounds are in late stages of development for treating MS. Fingolimod is an oral sphingosine-1-phosphate receptor modulator that has demonstrated superior efficacy compared with placebo and interferon β-1a in phase III studies. It has already been approved in the treatment of MS. This review focuses on advances in current and novel oral treatment approaches in MS. We summarily review the oral compounds in this study, focusing on the recent development, approval, and the clinical experience with fingolimod. Keywords: multiple sclerosis, oral compounds, fingolimod, sphingosine-1-phosphate, patient satisfaction, adherence

  13. From Easter Island to coated coronary stents: a remarkable saga.

    Science.gov (United States)

    Cantwell, John D

    2008-01-01

    Easter Island, even though it's in the middle of nowhere, is indeed a piece of the continent, as John Donne alluded to. In addition to contributing rapamycin to the medical field, the island is an example to the whole world of the consequences of affluent lifestyles, tribal wars, and ignorance of ecology. Jared Diamond expressed these thoughts best in his book, "Collapse:" The parallels between Easter Island and the whole modern world are chillingly obvious... All countries on earth today share resources and affect each other just as did Easter's dozen clans. Polynesian Easter Island was as isolated in the Pacific Ocean as the Earth is today in space. People see the collapse of Easter Island 's society as a metaphor; a worst-case scenario, for what may lie ahead for us in our own future. Some veteran Easter Island archaeologists like Claudio Cristina feel that Diamond's views are overly simplistic, commenting that he only spent a week on the island (versus 30 years for Cristina). Predatory Polynesian rats, earthquakes, tsunamis, variations in rainfall, diseases introduced by European sailing ships, could all have contributed to the near-demise of Easter Island. Tribal wars certainly didn't help, nor did slave-raiding parties from Peru. Only the eyes of the moai (Fig. 5) have seen it all, but the statues remain silent, as they have for over 1,000 years.

  14. España Republicana, una lectura de la Guerra Civil desde Argentina

    Directory of Open Access Journals (Sweden)

    María Teresa Pochat

    2006-11-01

    Full Text Available España Republicana was the organ of press of the Centro Republicano Español de Buenos Aires that, between 1918 and 1964, was essential means for the communication from the news of Spain in political, cultural, economic and social matters. In addition to constitute a scope of information, it gave rise to the dialogue between Spanish organizations of Argentina and it served like vehicle at the time of reuniting material of aid at the hardest moments of the Civil War and the postwar period. In its pages, the most outstanding personalities of the Republic appear like protagonists, mentioned in direct speech, in the heat of decision making and, often, like signers of collaborations dedicated in exclusive right to be published in the newspaper. Given the important as that España Republicana acted during the Civil War, we have believed useful to present in this monographic number the details of a work that comprised of an ample project of investigation of archives that it develops the Spanish Ministry of Culture, in collaboration with the Foundation "Claudio Sánchez-Albornoz". In synthesis, the task consisted of the microshooting and elaboration of an index commented of each one of more than thousand numbers available of the publication, with a detailed registry of contents, names and institutions, among other considered aspects, in order to facilitate to the investigators worldwide the location of the data of its interest.

  15. Behaviour of the Sm-Nd and Rb-Sr systems of the mafic-ultramafic layered sequence from Ribeirao dos Motas (Archaean), meridional craton Sao Francisco: evidences of mantle source enrichment and isotopic fractionation; Comportamento dos sistemas Sm-Nd e Rb-Sr da sequencia acamadada mafico-ultramafico Ribeirao dos Motas (Arqueano), craton Sao Francisco Meridional: evidencias de enriquecimento mantelico e fracionamento isotopico

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Mauricio Antonio; Carvalho Junior, Irneu Mendes de; Oliveira, Arildo Henrique de [Ouro Preto Univ., (UFOP), MG (Brazil). Dept. de Geologia]. E-mail: mauricio@degeo.ufop.br; Teixeira, Wilson [Sao Paulo Univ., SP (Brazil). Inst. de Geociencias. Dept. de Mineralogia e Geotectonica; Pimentel, Marcio Martins [Brasilia Univ., DF (Brazil). Inst. de Geociencias. Lab. de Geocronologia

    2004-10-15

    The Ribeirao dos Motas layered sequence (SARM) crops out in the southern part of the Sao Francisco Craton, Brazil. This sequence comprises phaneritic meta ultramafic and metamafic rocks, which, although slightly deformed and metamorphosed, retain primary igneous layers. Porphyritic rocks with idiomorphic pyroxene crystals and heteradcumulate and adcumulate textures are also present. Eighteen isotopic analyses were performed in the SARM, comprising rocks with primary (relict) textures, as well as rocks in amphibolite facies and retro-metamorphosed to green-schist facies. Seven samples yield a Sm/Nd isochron age of 2.79 +- 0.30 Ga (MSWD=1.2 e epsilon {sub Ndt}=+0.48), constraining the accretion time of the SARM rocks. The positive epsilon {sub Ndt} value coupled with the Rb/Sr evidence is consistent with mantle source relatively enriched in Nd and Sr isotopes. Nevertheless, some SARM samples display isotopic fractionation and disturbance, which can be ascribed to the following processes or their combinations: a) mobilization of the incompatible elements due to regional high grade metamorphism; b) isotopic changes during upper amphibolite facies overprint; c) isotopic resetting by low-grade fluids associated to the Claudio Shear zone, which is located nearby the SARM. (author)

  16. 亚洲艺术:走向全球的契机与可能——专访策展人陆蓉之

    Institute of Scientific and Technical Information of China (English)

    杨涓

    2011-01-01

    由北京今日美术馆,台北晟铭(UNEEC)文化教育基金会,鹿特丹世界艺术馆和台湾美术馆与威尼斯Claudio Buziol(克劳迪欧·布几奥)基金会联手合作,共同推出《未来通行证——从亚洲到全球》国际大展。此次展览呼应了第54届威尼斯国际艺术展的主题"ILLUMInations"(启发、光照与国家),展现了亚洲在艺术发展中,不止超越了国界,同时成为一个新的艺术宇宙中心。该展览分为两个部分,分别于Abbazia di San Gregorio(圣格雷戈斯修道院)以及Palazzo Mangilli-Valma

  17. The Origins of Kaldor Public Art Projects

    Directory of Open Access Journals (Sweden)

    Rebecca Coates

    2015-05-01

    Full Text Available Christo and Jeanne-Claude’s Wrapped Coast – One Million Square Feet, Little Bay, Sydney, Australia (1968-69 remains one of Kaldor Public Art Projects’ (KPAP most significant projects, both artistically and in its impact on the local and international art scene. A private not-for-profit foundation, Kaldor Public Art Projects has presented site-specific temporary art projects by leading international contemporary artists in Australia for over forty years. Some of these projects, such as Christo and Jeanne-Claude’s, were important milestones in the development of contemporary art in Australia. Not-for-profit foundations now play an increasingly important and visible role in the contemporary art world. This essay considers the circumstances that surrounded the inception of one of the earliest of these foundations, Kaldor Public Art Projects. It considers the factors that led to its creation. These include John Kaldor’s upbringing and experience as an émigré in Australia; his mentors, Sir Nicholas Sekers and Claudio Alcorso; and the influences on and of his collecting interests. The essay argues that gallerists such as Ileana Sonnabend played a pivotal role in the development of Kaldor’s collection and artistic interests. Kaldor’s collecting interests also played a key role in the development of the Art Projects. The role of the collector and patron are inextricably linked.

  18. Carlo Rubbia, former CERN Director-General, appointed Senator for life by the President of Italy.

    CERN Multimedia

    Antonella Del Rosso

    2013-01-01

    Today, the President of the Italian Republic Giorgio Napolitano appointed four new senators for life: the music director and conductor “maestro” Claudio Abbado, the neuroscientist Professor Elena Cattaneo, the renowned architect Renzo Piano and Professor Carlo Rubbia, who was CERN Director-General from 1989 to 1993.   Carlo Rubbia during his talk for the discovery of the W particle in 1983. In 1984, Carlo Rubbia, then head of the UA1 collaboration, was awarded the Nobel Prize in Physics, together with Simon van der Meer, for the discovery of the W and Z particles – at that time two important missing components of the Standard Model. During his term of office as Director-General, the Large Electron Positron collider was inaugurated and the four LEP experiments produced their first results. He also mounted the case for the new Large Hadron Collider, which in 2012 led to the discovery of a Higgs boson. In 1993, the last year of his mandate, the World Wide Web proto...

  19. Resistance to Soil-borne cereal mosaic virus in durum wheat is controlled by a major QTL on chromosome arm 2BS and minor loci.

    Science.gov (United States)

    Maccaferri, Marco; Ratti, Claudio; Rubies-Autonell, Concepcion; Vallega, Victor; Demontis, Andrea; Stefanelli, Sandra; Tuberosa, Roberto; Sanguineti, Maria Corinna

    2011-08-01

    Soil-borne cereal mosaic (SBCM) is a viral disease, which seriously affects hexaploid as well as tetraploid wheat crops in Europe. In durum wheat (Triticum durum Desf.), the elite germplasm is characterized by a wide range of responses to SBCMV, from susceptibility to almost complete resistance. In this study, the genetic analysis of SBCMV resistance was carried out using a population of 181 durum wheat recombinant inbred lines (RILs) obtained from Meridiano (resistant) × Claudio (moderately susceptible), which were profiled with SSR and DArT markers. The RILs were characterized for SBCMV response in the field under severe and uniform SBCMV infection during 2007 and 2008. A wide range of disease reactions (as estimated by symptom severity and DAS-ELISA) was observed. A large portion of the variability for SBCMV response was explained by a major QTL (QSbm.ubo-2BS) located in the distal telomeric region of chromosome 2BS near the marker triplet Xbarc35-Xwmc661-Xgwm210, with R(2) values ranging from 51.6 to 91.6%. The favorable allele was contributed by Meridiano. Several QTLs with minor effects on SBCMV response were also detected. Consistently with the observed transgressive segregation, the resistance alleles at minor QTLs were contributed by both parents. The presence and effects of QSbm.ubo-2BS were validated through association mapping in a panel of 111 elite durum wheat accessions.

  20. Thermal and lighting perception in four fully glazed office buildings in Santiago, Chile

    Directory of Open Access Journals (Sweden)

    Claudio Vásquez

    2013-12-01

    Full Text Available Corresponding author: Claudio Vásquez, School of Architecture, Catholic University of Chile. 1916 El Comendador str. Providencia, Santiago, ZIP: 7530091, Chile. Tel.: +56 9 92826305; E-mail: clvasque@uc.cl This paper is part of a general research project whose main objective is to establish a baseline for post-occupancy energy consumption and indoor environmental quality for office buildings in Santiago, Chile. This study aims at understanding how architectonical variables relate to, and can even determine, user comfort perception. Thus, one-year continuous monitoring in several floors at four office buildings was performed and seasonal surveys were completed. Survey participants were asked a series of questions regarding spatial orientation and comfort perception in their workspace. The data from the comfort survey and onsite measurements such as season of the year, case study, type of workspace and possibility of an outdoor view from the workstation were contrasted with the components obtained by a Principal Component Analysis (PCA. Three components were selected from the PCA, and three Maps of Perception (MP were produced. These maps were then analyzed and interpreted so as to obtain information on the general perception of thermal and lighting comfort at workspaces within several office buildings in Santiago.

  1. Highlights and Conclusions of the Chalonge 13th Paris Cosmology Colloquium

    CERN Document Server

    de Vega, H J

    2010-01-01

    The 13th Chalonge Paris Cosmology Colloquium was held at the historic Perrault building of Observatoire de Paris on 23-25 July 2009. The Colloquium was held in the spirit of the Chalonge School, putting together real cosmological and astrophysical data and hard theory predictive approach in the framework of the Standard Model of the Universe. Peter Biermann, James Bullock, Claudio Destri, Hector de Vega, Massimo Giovannini, Sasha Kashlinsky, Eiichiro Komatsu, Anthony Lasenby and Norma G. Sanchez present here their highlights of the Colloquium. The summary and conclusions by H. J. de Vega, M. C. Falvella and N. G. Sanchez stress among other points: (i) the primordial CMB fluctuations are almost gaussian, large primordial non-gaussianity and large running index are strongly disfavored. The primordial graviton ratio r is predicted in the effective theory of inflation to be between 0.021 and 0.053, at reach of the next CMB observations. (ii) Dark energy observations are consistent with the cosmological constant. ...

  2. PREFACE: Young Researcher Meeting, Trieste 2013

    Science.gov (United States)

    Agostini, F.; Antolini, C.; Aversa, R.; Cattani, G.; Martinelli, M.; Mazzaferro, L.; Migliaccio, M.; Paci, F.; Pietrobon, D.; Ricci Pacifici, D.; Stellato, F.; Veneziani, M.

    2013-12-01

    YRM logo The Young Researcher Meeting (www.yrmr.it) has been a rapidly growing event for the last few years. Together with other initiatives which have emerged in several research areas, the young researcher meeting marks the awareness and the desire of PhD students, postdoctoral fellows and young researchers to play a major role in scientific progress. Devoted to the discussion and the interchange of new developments and ideas in physics, the meeting is primarily aimed at graduate students and postdoctoral researchers, who are encouraged to present their work in an informal atmosphere. One of the main purposes of the conference is to create an international network of young researchers, both experimentalists and theorists, and fruitful collaborations across the different branches of physics. Born in Rome in 2009, after three editions that strengthened it, the Young Researcher Meeting 2013 was held in Trieste. Propelled by the past success, the fourth meeting was a two-day conference on 3-4June. It was sponsored by the International School for Advanced Studies - SISSA - and the University of Padova, thus acquiring an even further international drive. In this volume, we collect some of the contributions that were presented at the conference. They cover topics in astrophysics and cosmology, particle and theoretical physics, soft and condensed matter, biophysics and medical physics. YRM Organising and Editorial Committee Fabio Agostini (fabio.agostini@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma, Italy Claudia Antolini (claudia.antolini@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Rossella Aversa (raversa@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Via Bonomea 265, 34136 Trieste, Italy Giordano Cattani (giordano.cattani@gmail.com) Matteo Martinelli (mmartin@sissa.it) SISSA - Scuola Internazionale Superiore di

  3. PREFACE: Young Researcher Meeting in Rome 2012

    Science.gov (United States)

    Agostini, Fabio; Cattani, Giordano; Mazzaferro, Luca; Migliaccio, Marina; Pietrobon, Davide; Ricci Pacifici, Daniel; Stellato, Francesco; Veneziani, Marcella

    2012-10-01

    Conference logo At its third edition, the Young Researcher Meeting in Rome (YRMR) proves to be a growing event in the Italian scientific panorama. The high-quality content of the abstracts submitted to the scientific committee resulted in an exciting conference, held, for the second time, at the University of Rome 'Tor Vergata' on 20 January 2012. A busy schedule covered a large variety of cutting-edge science topics: fundamental interactions, particle physics, cosmology, astrophysics, condensed matter and biomedical physics. The broad range of the subjects discussed is the distinctive feature of the YRMR, a meeting aimed at enhancing the synergy among complementary branches of science by stimulating a fruitful exchange between theoretical, experimental and computational physics. Promoting collaborations between PhD students, postdoctoral fellows and young researchers creates a solid scientific network with an open-minded approach to discovery. In this volume, we collect the contributions that have been presented both in the form of talks and of posters. YRMR Organising and Editorial Committee Fabio Agostini (fabio.agostini@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Giordano Cattani (giordano.cattani@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' INFN sezione di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Luca Mazzaferro (luca.mazzaferro@roma2.infn.it) Dipartimento di Fisica, Università di Roma 'Tor Vergata' INFN sezione di Roma 'Tor Vergata' Via della Ricerca Scientifica 1, 00133 Roma Italy Marina Migliaccio (migliaccio@ifca.unican.es) Instituto de Fisica de Cantabria, Edificio Juan Jorda, Avenida de los Castros, E-39005 Santander, Cantabria Spain Davide Pietrobon (davide.pietrobon@jpl.nasa.gov) Jet Propulsion Laboratory - California Institute of Technology 4800 Oak Grove Drive 169-237 91109 Pasadena, CA USA Daniel Ricci Pacifici

  4. PREFACE: Young Researcher Meeting, Trieste 2014

    Science.gov (United States)

    Agostini, F.; Antolini, C.; Aversa, R.; Cattani, G.; Di Stefano, M.; Longobardi, M.; Martinelli, M.; Miceli, A.; Migliaccio, M.; Paci, F.; Pietrobon, D.; Pusceddu, E.; Stellato, F.

    2014-12-01

    skills. Engaging the public and finding unconventional ways to communicate results turn out to be real assets in improving the quality of presentation of current research to peers, as well as to the general public. In this volume, we collect part of the contributions that have been presented at the conference. They cover topics in astrophysics and cosmology, particle and theoretical physics, soft and condensed matter, medical physics and applied physics. Given the recent experimental achievements in particle physics and cosmology, several contributions were focused on the latest results obtained in these fields, presenting the impact of experiments such as LHC and Planck to the community of young researchers and forecasting the future goals in these areas of research. Particular interest was aroused by the session fully dedicated to applied Physics and conservation of cultural assets. Besides the intrinsic scientific value of the discussed topics, the increasing relative weight of the applied Physics session is a demonstration of the benefits that fundamental science brings to the community. YRM Organising and Editorial Committee Fabio Agostini (fabio.agostini31@gmail.com) Telespazio A Finmeccanica Thales Company Claudia Antolini (claudia.antolini@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati and Fudan University Rossella Aversa (raversa@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Giordano Cattani (giordano.cattani@gmail.com) Marco Di Stefano (distefan@sissa.it) SISSA - Scuola Internazionale Superiore di Studi Avanzati Maria Longobardi (marialongobardi@gmail.com) Department of Condensed Matter Physics, University of Geneva Matteo Martinelli (martinelli@thphys.uni-heidelberg.de) SISSA - Scuola Internazionale Superiore di Studi Avanzati and Institut fur Theoretische Physik Alice Miceli (alice.miceli@uniroma2.it) Physics Department, University of Rome Tor Vergata Marina Migliaccio (mm858@ast.cam.ac.uk) Institute of Astronomy and

  5. Crenças sobre ensino-aprendizagem de Língua Inglesa: o que pensam quatro professores do ensino médio de escolas públicas

    Directory of Open Access Journals (Sweden)

    Janete Strutz

    2012-04-01

    Full Text Available O presente trabalho propõe analisar e discutir possíveis crenças encontradas em quatro profissionais formados em Letras sobre o processo de ensino-aprendizagem de Língua Inglesa. Ao dialogar com autores como Ana Maria Ferreira Barcelos, Fabio Madeira e Almeida Filho, defino crenças como princípios pessoais, declarados ou inferidos pelo discurso ou pela ação,  aceitos como verdades, e que exercem influência sobre o que os indivíduos pensam e o que eles fazem. As crenças são dinamicamente construídas a partir das experiências que estes indivíduos vivenciam durante toda a sua história de vida, a partir de características pessoais, como a idade, o sexo, a formação ou a personalidade. Este trabalho também objetiva contribuir para caminhos de ação e reflexão da prática de ensinar do professor, os recursos e os métodos utilizados levando em consideração que diferentes posturas metodológicas e concepções que podem permear o trabalho docente do professor de língua inglesa, bem como de sua própria formação acadêmica e que as crenças podem servir de barreiras ou auxiliar o processo e podem sofrer alterações pela experiência que as pessoas vivenciam.Palavras-chave: letras; Língua Inglesa; ensino-aprendizagem de Língua Inglesa; professor de línguas estrangeiras; Ana Maria Barcelos. 

  6. 《美容整形外科》(Aesthetic Plastic Surgery)2001年第25卷第4期目录

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Aesthetic Plastic Surgery Volume 25 , Number 4, 2001 249 The Value of a New Filler Material in Corrective and Cosmetic Surgery: DermaLive and DermaDeep Catherine Bergeret-Galley , Xavier Latouche , Yves-Gérard Illouz 256 Fat Transplantation for Soft Tissue Augmentation in the Lower Limbs M. Stampos, P. Xepoulias 262 The Effect of Reduction of the Peripheral Fat Content by Liposuction-Assisted Lipectomy (SAL) on Serum Leptin Levels in the Postoperative Period: A Prospective Study Ran Talisman, Nik Belinson, Dalit Modan-Moses, Hana Canti, Arie Orenstein, Zohar,Barzilai, Gideon Parret 266 Short Columella Nasolabial Complex in Aesthetic Rhinoplasty A. Aldo Mottura 273 Nasal Reconstruction After Epithelioma Salvador Rodriguez-Camps 278 PVP Breast Implants After Two Years: Initial Results of a Prospective Study Henrik Menke , H. GrUbmeyer, E. Biemer, R. R. Olbrisch 283 Mammographic Findings Following Reduction Mammoplasty Dimitrios Danikas, Spero J. V. Theodorou, George Kokkalis, Katerina Vasiou, Konstantina K yriakopoulou 286 Unsatisfactory Results of Periareolar Mastopexy With or Without Augmentation and Reduction Mammoplasty: Enlarged Areola With Flattened Nipple Cihat N. Baran, Fatih Peker , Turgut Ortak , Omer Sensoz , Namik K. Baran 290 Postoperative Compression After Breast Augmentation Bassem Nathan, Shiva Singh 292 Breast Augmentation with Fresh-Frozen Homologous Fat Grafts J. Haik, R. Talisman, J. Tamir, J. Frand, E. Gazit, J. Schibi, A. Glicksman, A. Orenstein 295 Upper Eyelid Mycobacterial Infection Following Oriental Blepharoplasty in a Pulmonary Tuberculosis Patient Samuel H. T. Chen, Chun-Hua Wang, Hung-Chi Chen, George C. J. Weng, Paul-Yann Lin, Fu-Chan Wei 299 Clinical Facial Photography in a Small Office:Lighting Equipment and Technique Fabio Meneghini 307 Specific Requirements for Preoperative and Postoperative Photos Used in Publication Irene Talamas and Luis Pando 311 Announcements

  7. Barrier effect of Esoxx® on esophageal mucosal damage: experimental study on ex-vivo swine model

    Directory of Open Access Journals (Sweden)

    Di Simone MP

    2012-06-01

    Full Text Available Massimo P Di Simone,1 Fabio Baldi,2,3 Valentina Vasina,4 Fabrizio Scorrano,5 Maria Laura Bacci,5 Antonella Ferrieri,6 Gilberto Poggioli11Department of General Surgery and Transplants, 2Centre for the Study and Therapy of the Esophageal Diseases, 3GVM Care and Research, MCH Cotignola (RA, 4Department of Pharmacology, Alma Mater Studiorum, University of Bologna, Bologna, 5Department of Veterinary Medical Science – DMSVET – University of Bologna, Bologna, 6Clinical Research Department, Alfa Wassermann Spa, Bologna, ItalyAbstract: The aim of the present study was to assess the potential barrier effect of Esoxx®, a new nonprescription medication under development for the relief of gastroesophageal reflux symptoms. Esoxx is based on a mixture of hyaluronic acid and chondroitin sulfate in a bioadhesive suspension of Lutrol® F 127 polymer (poloxamer 407 which facilitates the product adhesion on the esophageal mucosa. The mucosal damage was induced by 15 to 90 minutes of perfusion with an acidic solution (HCl, pH 1.47 with or without pepsin (2000 U/mL, acidified to pH 2; Sigma-Aldrich. Mucosal esophageal specimens were histologically evaluated and Evans blue dye solution was used to assess the permeability of the swine mucosa after the chemical injury. The results show that: (1 esophageal mucosal damage is related to the perfusion time and to the presence of pepsin, (2 mucosal damage is associated with an increased permeability, documented by an evident Evans blue staining, (3 perfusion with Esoxx is able to reduce the permeability of the injured mucosa, even after saline washing of the swine esophagus. These preliminary results support further clinical studies of Esoxx in the topical treatment of gastroesophageal reflux symptoms.Keywords: bioadhesion, hyaluronic acid, Evans blue dye, animal model, esophagus, reflux esophagitis

  8. Assessment of Poa annua resistance to clethodim in Costa Rica.

    Directory of Open Access Journals (Sweden)

    Ana María Rodríguez-Ruiz

    2015-06-01

    Full Text Available The objective of this study was to check for the presence of resistance to clethodim in Poa annua populations observed in onion fields in the highlands of Cartago, Costa Rica. Two experiments were conducted; the first one was carried out, in 2007, in a greenhouse at the Fabio Baudrit Moreno Agricultural Experiment Station (EEAFBM, in Spanish, with seeds of plants from a farm where clethodim exercised good control (S population, and from another farm where clethodim showed a deficient control (R population. Both S and R populations were treated with different doses of clethodim (0.5X, 1.0X, 1.5X and 2.0X, being X the recommended commercial dose. In this experiment, control of the R population was 44% and 17% at doses of 1.5X and 2.0X, respectively, whereas control of the S population was 100% at either of those doses. The second experiment was carried out in 2009, seeds of two other P. annua populations were collected in a similar way: one population from an area where weed control was satisfactory (S, and the other population from an area of the farm where control was deficient (R. Seeds were sown, depending on the type, in plastic pots and sprayed with clethodim at doses of: 0. 1X, 2X, 4X, 8X, and 16X. There were significant differences in the reactions to clethodim of both P. annua populations The S population showed a higher percentage of control and less surviving plants than the R population. Several plants of the R population resisted up to 16X commercial doses of clethodim. Results of both experiments suggest the presence of P. annua populations resistant to clethodim.

  9. Catalytically active bovine serum amine oxidase bound to fluorescent and magnetically drivable nanoparticles

    Directory of Open Access Journals (Sweden)

    Bidollari E

    2012-05-01

    Full Text Available Giulietta Sinigaglia1, Massimiliano Magro1, Giovanni Miotto1, Sara Cardillo1, Enzo Agostinelli2,3, Radek Zboril4, Eris Bidollari2,3, Fabio Vianello11Department of Biological Chemistry, University of Padua, Padua, Italy; 2Istituto Pasteur-Fondazione Cenci Bolognetti, Department of Biochemical Sciences "A. Rossi Fanelli", SAPIENZA University of Rome, Rome, Italy; 3CNR, Institute Biology and Molecular Pathology, Rome, Italy; 4Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry, Palacky University, Olomouc, Czech RepublicAbstract: Novel superparamagnetic surface-active maghemite nanoparticles (SAMNs characterized by a diameter of 10 ± 2 nm were modified with bovine serum amine oxidase, which used rhodamine B isothiocyanate (RITC adduct as a fluorescent spacer-arm. A fluorescent and magnetically drivable adduct comprised of bovine serum copper-containing amine oxidase (SAMN–RITC–BSAO that immobilized on the surface of specifically functionalized magnetic nanoparticles was developed. The multifunctional nanomaterial was characterized using transmission electron microscopy, infrared spectroscopy, mass spectrometry, and activity measurements. The results of this study demonstrated that bare magnetic nanoparticles form stable colloidal suspensions in aqueous solutions. The maximum binding capacity of bovine serum amine oxidase was approximately 6.4 mg g-1 nanoparticles. The immobilization procedure reduced the catalytic activity of the native enzyme to 30% ± 10% and the Michaelis constant was increased by a factor of 2. We suggest that the SAMN–RITC–BSAO complex, characterized by a specific activity of 0.81 IU g-1, could be used in the presence of polyamines to create a fluorescent magnetically drivable H2O2 and aldehydes-producing system. Selective tumor cell destruction is suggested as a potential future application of this system.Keywords: amine oxidase, hydrogen peroxide production, superparamagnetic

  10. Cultura, política y modernidad / Cultura, medios y sociedad

    Directory of Open Access Journals (Sweden)

    Claudia Montagut

    1999-01-01

    Full Text Available Jesús Martín Barbero y otros. Cultura, política y modernidad Ces, Universidad Nacional Bogotá. 1998. 427 págs. Los ensayos que se presentan en Cultura, medios y sociedad contienen catorce artículos de diferentes autores: Fabio López de la Roche, Beatriz Sarlo, William Rowe, Ana María Ochoa Gautier, Ana María Lalinde, Jaime Eduardo Jaramillo, Jorge Orlando Melo, Jairo Chaparro Valderrama, Germán Muñoz, José Fernando Serrano, Luz Guillermina Sinning. Este libro presenta un énfasis en los medios de comunicación (en su acepción más amplia desde los libros hasta el internet como corolario de los cambios de lo que se ha llamado las tradiciones culturales, las prácticas de sociabilidad urbana y popular para una aparición de los puntos de vista de lo local, el  multiculturalismo y la globalización. / Gabriel Restrepo y otros. Cultura, medios y sociedad. Ces, Universidad Nacional Bogotá. 1998. 319 págs. Cultura, política y modernidad abre con una interesante discusión sobre "las ciencias naturales y las ciencias del espíritu" como las denomina su autor Hans Ulrich Gumbrecht , en la cual se realiza una reflexión sobre las maneras "posmodernas", "estructuralistas" y" deconstruccionistas" de escribir, empezando con el ya manido chiste de Sokal.

  11. Cultura, política y modernidad / Cultura, medios y sociedad

    Directory of Open Access Journals (Sweden)

    Claudia Montagut

    2010-10-01

    Full Text Available Jesús Martín Barbero y otros. Cultura, política y modernidad Ces, Universidad Nacional Bogotá. 1998. 427 págs. Los ensayos que se presentan en Cultura, medios y sociedad contienen catorce artículos de diferentes autores: Fabio López de la Roche, Beatriz Sarlo, William Rowe, Ana María Ochoa Gautier, Ana María Lalinde, Jaime Eduardo Jaramillo, Jorge Orlando Melo, Jairo Chaparro Valderrama, Germán Muñoz, José Fernando Serrano, Luz Guillermina Sinning. Este libro presenta un énfasis en los medios de comunicación (en su acepción más amplia desde los libros hasta el internet como corolario de los cambios de lo que se ha llamado las tradiciones culturales, las prácticas de sociabilidad urbana y popular para una aparición de los puntos de vista de lo local, el  multiculturalismo y la globalización. / Gabriel Restrepo y otros. Cultura, medios y sociedad. Ces, Universidad Nacional Bogotá. 1998. 319 págs. Cultura, política y modernidad abre con una interesante discusión sobre "las ciencias naturales y las ciencias del espíritu" como las denomina su autor Hans Ulrich Gumbrecht , en la cual se realiza una reflexión sobre las maneras "posmodernas", "estructuralistas" y" deconstruccionistas" de escribir, empezando con el ya manido chiste de Sokal.

  12. Determination of the capability of common bean “amachamiento” (Aphelenchoides besseyi Christie of being seed-transmitted.

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    Néstor Felipe Chaves-Barrantes

    2015-12-01

    Full Text Available The objective of this research was to determine the capability of Aphelenchoides besseyi of being seed-transmitted in common bean. During 2007 and 2008, seeds were collected from nematode-infested common bean plants (cv. Cabécar previously showing characteristic symptoms, in commercial plantations of the Brunca region of Costa Rica (southeastern area of the country. Between September 2008 and September 2009 the seeds were sowed in plastic pots in a greenhouse located in Veracruz, Pérez Zeledón, Costa Rica. Once seeds germinated, plants were observed weekly to determine the appearance of “amachamiento” symptoms and detect the cases of disease transmission by seed. To support the previous work, seeds from “amachamiento” diseased plants (cv. Cabécar were collected in commercial common bean plantations in five localities of the Brunca region of Costa Rica in 2014. The seeds were carried to Estación Experimental Agrícola Fabio Baudrit Moreno of Universidad de Costa Rica located in Alajuela, where they were examined in a laboratory to determine the presence of A. besseyi specimens. Contrary to indicated for A. besseyi in rice and pastures, crops in which this pathogen is seed-transmitted, in common bean it was not possible find specimens of this nematode nor diseased plants from seeds of infested plants. The results obtained indicate that, under these experimental conditions, seeds are not an effective way for the transmission and dissemination of the “amachamiento” disease in common bean.

  13. From the history of the recognitions of the remains to the reconstruction of the face of Dante Alighieri by means of techniques of virtual reality and forensic anthropology

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    Stefano Benazzi

    2007-07-01

    Full Text Available The work consists of the reconstruction of the face of the great poet called Dante Alighieri through a multidisciplinary approach that matches traditional techniques (manual ones, usually used in forensic anthropology, with digital methodologies that take advantage of technologies born in manufacturer-military fields but that are more and more often applied to the field of the cultural heritage. Unable to get the original skull of Dante, the work started from the data and the elements collected by Fabio Frassetto and Giuseppe Sergi, two important anthropologists, respectively at the University of Bologna and Rome, in an investigation carried out in 1921, sixth century anniversary of his death, on the remains of the poet collected in Ravenna. Thanks to this, we have a very accurate description of Dante’s bones, including 297 metric data inherent to the whole skeleton, some photographs in the scale of the skull, the various norms and many other bones, as well as a model of the skull subsequently realized by Frassetto. According to these information, a geometric reconstruction of Dante Alighieri skull including the jaw was carried out through the employment and integration of the instruments and technologies of the virtual reality, and from this the relative physical model through fast prototype was realized. An important aspect of the work regards in a particular manner the methodology of 3D modelling proposed for the new reconstruction of the jaw (not found in the course of the 1921 recognition, starting from a reference model. The model of the skull prototype is then useful as the basis for the successive stage of facial reconstruction through the traditional techniques of forensic art.

  14. Evaluación de sustratos para almácigos de hortalizas

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    Gustavo Quesada Rold\\u00E1n

    2005-01-01

    Full Text Available Se realizó una evaluación agronómica de almácigos de hortalizas (tomate, pepino, lechuga y brócoli establecidos en diferentes sustratos, en la Estación Experimental Fabio BaudritMoreno, Alajuela, Costa Rica, bajo condiciones de invernadero, del 12 de abril al 7 de mayo del 2004. Se utilizaron bandejas plásticas de 128 celdas de forma piramidal invertida. El diseño experimental utilizado fue un irrestricto completamenteal azar con cuatro repeticiones. Ala edad de transplante seevaluaron variables de vigor de germinación, desarrollo deplanta y calidad de adobe. Los sustratos que permitieron elmejor desarrollo de las plantas en los cultivos de brócoli, pepino y tomate fueron abono orgánico Juan Viñas; lombricom-post + abono orgánico Juan Viñas + granza; y abono orgánicoJuan Viñas + granza. Los sustratos aserrín de melina madurado + suelo + granza; y peat moss + perlita fueron los mejoresmedios para almácigos de lechuga. Se observó además en lossustratos abono orgánico Juan Viñas + aserrín de melina ma-durado + granza; bagazo + aserrín de melina madurado + abono orgánico Juan Viñas; y aserrín de melina madurado + fibrade coco + ceniza, una excelente calidad de adobe, aunque undesarrollo de la planta no tan vigoroso. Los sustratos “tierrafermentada”; fibra de coco; sustrato comercial 2; y bagazo +fibra de coco + piedra pómez fueron los que más limitaron elestablecimiento de las plantas de almácigo.

  15. Evaluación agronómica de trece genotipos de camote (Ipomoea batatas L

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    Rolbin Castillo Matamoros

    2014-12-01

    Full Text Available El objetivo del presente trabajo fue caracterizar desde el punto de vista agronómico, 13 genotipos de camote para su cultivo en Costa Rica. Diez fueron introducidos de la Unidad de Micropropagación de la Universidad Estatal de Carolina del Norte, y cultivados por primera vez en Costa Rica, 2 conocidos como “Exportación y Zanahoriaˮ son de introducción reciente, pero se han cultivado en el país por al menos 5 años y el restante Criollo es el que ocupa actualmente la mayor área de siembra. El trabajo se llevó a cabo en la Estación Experimental Fabio Baudrit de la Universidad de Costa Rica, ubicada en la provincia de Alajuela. Los tratamientos se dispusieron en el campo en un diseño de bloques completos al azar, con 13 genotipos y 4 repeticiones. El análisis de varianza mostró que los genotipos difirieron significativamente (p=0,0001 en todas las variables evaluadas: peso fresco y seco foliar; peso fresco y seco de raíz reservante; número de raíces reservantes; peso de raíz reservante/ planta; contenido de materia seca y rendimiento (t.ha -1 . Todos los cultivares evaluados superaron el rendimiento de la variedad Criollo (6 t.ha -1 y el promedio nacional (5 a 7,8 t.ha -1 , con rendimientos entre 12 y 48 t.ha -1 . Algunos de los cultivares son promisorios para su cultivo en Costa Rica, no solo con base en su rendimiento, sino debido a su color de pulpa, amarilla o anaranjada, asociado a un mayor contenido de carotenos.

  16. Lormetazepam addiction: data analysis from an Italian medical unit for addiction

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    Faccini M

    2012-06-01

    Full Text Available Marco Faccini,1 Roberto Leone,2 Benedetta Pajusco,1 Gianluca Quaglio,1 Rebecca Casari,1 Anna Albiero,1 Monia Donati,2 Fabio Lugoboni11Department of Internal Medicine, Addiction Unit, 2Pharmacology Unit, Reference Center for Education and Communication within the World Health Organization Program for International Drug Monitoring, University Hospital of Verona, Verona, ItalyBackground: The purpose of this study was to determine, in the context of a hospital addiction unit, which benzodiazepines were abused and to look for correlations with the characteristics of detoxified patients.Methods: A retrospective study was carried out using the database of hospital admissions to the addiction unit for detoxification from 2003 to 2010.Results: Of 879 admissions to the addiction unit during the seven-year period, 281 were for benzodiazepines. The percentage of patients addicted only to benzodiazepines was higher among females than males. Benzodiazepine consumption had started as a drug addiction behavior in only 10% of cases. The main sources of prescription identified were general practitioners (52% of cases or compliant pharmacists (25%. Overall, 15 different benzodiazepines were abused, with lormetazepam being the most commonly used (by 123 patients, 43.8% of the total.Conclusion: Our data show that, outside the population of multidrug addicts, there is an underestimated group of chronic benzodiazepine consumers who are often not referred to medical institutions for treatment. Even in the group of patients addicted to one substance only, we observed an abnormal number of requests for detoxification from lormetazepam, which appears to be more "popular" than other benzodiazepines. This drug should be prescribed according to stricter criteria and submitted to closer control.Keywords: lormetazepam, benzodiazepines, addiction, inpatient detoxification

  17. Is oxycodone/naloxone effective and safe in managing chronic pain of a fragile elderly patient with multiple skin ulcers of the lower limbs? A case report 

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    Guerriero F

    2015-08-01

    Full Text Available Fabio Guerriero,1,2 Niccolo Maurizi,1 Matthew Francis,1 Carmelo Sgarlata,1 Giovanni Ricevuti,1,2 Mariangela Rondanelli,2,3 Simone Perna,2,3 Marco Rollone21Department of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 2Azienda di Servizi alla Persona, Istituto di Cura Santa Margherita of Pavia, 3Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, University of Pavia, Pavia, Italy Abstract: Skin ulcers are a common issue in the elderly, as physiological loss of skin elasticity, alterations in microcirculation, and concomitant chronic diseases typically occur in advanced age, thereby predisposing to these painful lesions. Wound-related pain is often associated with skin ulcers and negatively impacts both the patient’s quality of life and, indirectly, wound healing. Pain management is an ongoing issue in the elderly, and remains underestimated and undertreated in this fragile population. Recent guidelines suggest the use of opioids as the frontline treatment of moderate and severe pain in nononcological pain in the elderly. However, due to the concerns of adverse reactions, drug interactions, and addiction, clinicians frequently hesitate to prescribe opioids. This case report describes an elderly diabetic patient with multiple ulcers of the lower limbs suffering wound-related pain. In our report, oxycodone/naloxone has proved to be an effective and safe drug, providing pain relief as well as increased compliance when redressing wounds and faster healing compared to that in similar patients. Our case provides anecdotal evidence, supported by other studies, to justify future, larger studies on chronic pain using this therapy. Keywords: chronic pain, skin ulcers, elderly, opioids, oxycodone, naloxone

  18. DEVELOPMENT OF HEARING COMPETENCE

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    Fabio Ernesto Martínez Navas

    2011-05-01

    Full Text Available Es necesario buscar nuevos caminos para motivar a los profesores y a los estudiantes para que el entrenamiento auditivo se convierta en juegos de audición e improvisación, de este modo se desarrolla la competencia auditiva. Se establece la diferencia entre el oír y el escuchar y se presentan unos pasos indispensables para este propósito. Primero se hace un calentamiento, luego un entrenamiento y por último, se llega a la competencia auditiva. El pensamiento, la inteligencia y la memoria musical son indispensables para la formación del oído musical. Se debe pasar de la improvisación al dictado oral, luego al reconocimiento audiovisual para finalmente proceder a tomar dictados escritos. La escritura desarrolla la audiación cuando el sonido físico no está presente, de este modo se afina la escucha consciente representado por el pensamiento musical, es decir las imágenes sonoras, ¿cómo suena un acorde mayor?, ¿cuál es la sonoridad de una quinta justa melódica o armónica?; la audición convierte el oír en escuchar. La metodología FABERMANA[1] es la nueva propuesta, gracias al trabajo de aula en los espacios académicos de Formación Teórico Auditiva y Entrenamiento Auditivo. Actualmente hay algunos centros educativos de Educación Musical que están probando la metodología con un significativo éxito.     [1] FABERMANA: Desarrollo de la competencia auditiva, propuesta metodológica de Fabio E. Martínez N.

  19. Effects of maintenance lithium treatment on serum parathyroid hormone and calcium levels: a retrospective longitudinal naturalistic study

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    Albert U

    2015-07-01

    Full Text Available Umberto Albert,1 David De Cori,1 Andrea Aguglia,1 Francesca Barbaro,1 Fabio Lanfranco,2 Filippo Bogetto,1 Giuseppe Maina3 1Anxiety and Mood Disorders Unit, Rita Levi Montalcini Department of Neuroscience, University of Turin, Torino, Italy; 2Division of Endocrinology, Diabetology and Metabolism, Department of Medical Sciences, University of Turin, Torino, Italy; 3Department of Mental Health, San Luigi-Gonzaga Hospital, University of Turin, Orbassano, Italy Objective: The aim of this retrospective longitudinal naturalistic study was to evaluate the effects of maintenance lithium treatment on parathyroid hormone (PTH and calcium levels. Methods: A retrospective longitudinal naturalistic study design was used. Data were collected from the database of a tertiary psychiatric center covering the years 2010–2014. Included were bipolar patients who had never been exposed to lithium and had lithium started, and who had PTH, and total and ionized calcium levels available before and during lithium treatment. Paired t-tests were used to analyze changes in PTH and calcium levels. Linear regressions were performed, with mean lithium level and duration of lithium exposure as independent variables and change in PTH levels as dependent variable. Results: A total 31 patients were included. The mean duration of lithium treatment was 18.6±11.4 months. PTH levels significantly increased during lithium treatment (+13.55±14.20 pg/mL; the rate of hyperparathyroidism was 12.9%. Neither total nor ionized calcium increased from baseline to follow-up; none of our patients developed hypercalcemia. Linear regressions analyses did not show an effect of duration of lithium exposure or mean lithium level on PTH levels. Conclusion: Lithium-associated stimulation of parathyroid function is more common than assumed to date. Among parameters to be evaluated prior to lithium implementation, calcium and PTH should be added. Keywords: bipolar disorder, follow-up study, lithium

  20. The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction

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    Paolo Verdecchia

    2008-10-01

    Full Text Available Paolo Verdecchia1, Fabio Angeli1, Giovanni Mazzotta1, Giorgio Gentile2, Gianpaolo Reboldi21Department of Cardiology, Clinical Research Unit ‘Preventive Cardiology’, Hospital ‘Santa Maria della Misericordia’, and Fondazione Umbra Cuore e Ipertensione – AUCI Onlus, Perugia, Italy; 2Department of Internal Medicine University of Perugia, ItalyAbstract: An association has been shown between plasma renin activity (PRA and the risk of cardiovascular disease. There is also evidence that angiotensin II exerts detrimental effects on progression and instabilization of atherosclerotic plaque. The renin-angiotensin system (RAS can be inhibited through inhibition of angiotensin I (Ang I generation from angiotensinogen by direct renin inhibitors, inhibition of angiotensin II (Ang II generation from angiotensin I by angiotensin-converting enzyme inhibitors and finally by direct inhibition of the action of Ang II receptor level. Aliskiren, the first direct renin inhibitor to reach the market, is a lowmolecular-weight, orally active, hydrophilic nonpeptide. Aliskiren blocks Ang I generation, while plasma renin concentration increases because the drugs blocks the negative feed-back exerted by Ang II on renin synthesis. Because of its long pharmacological half-life, aliskiren is suitable for once-daily administration. Its through-to-peak ratio approximates 98% for the 300 mg/day dose. Because of its mechanism of action, aliskiren might offer the additional opportunity to inhibit progression of atherosclerosis at tissue level. Hypertension is an approved indication for this drug, which is also promising for the treatment of heart failure. The efficacy of this drug in reducing major clinical events is being tested in large ongoing clinical trials.Keywords: plasma renin activity, renin angiotensin system, aliskiren, angiotensinogen, renin, hypertension, heart failure, diabetes

  1. Frequency-doubling technology perimetry and multifocal visual evoked potential in glaucoma, suspected glaucoma, and control patients

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    Kanadani FN

    2014-07-01

    Full Text Available Fabio N Kanadani,1 Paulo AA Mello,1 Syril K Dorairaj,2 Tereza CM Kanadani31Federal University of Sao Paulo, Sao Paulo, Brazil; 2Mayo Clinic, Department of Ophthalmology, Jacksonville, Florida, USA; 3Sao Jose University Hospital, Belo Horizonte, BrazilIntroduction: The gold standard in functional glaucoma evaluation is standard automated perimetry (SAP. However, SAP depends on the reliability of the patients’ responses and other external factors; therefore, other technologies have been developed for earlier detection of visual field changes in glaucoma patients. The frequency-doubling perimetry (FDT is believed to detect glaucoma earlier than SAP. The multifocal visual evoked potential (mfVEP is an objective test for functional evaluation.Objective: To evaluate the sensitivity and specificity of FDT and mfVEP tests in normal, suspect, and glaucomatous eyes and compare the monocular and interocuar mf VEP.Methods: Ninety-five eyes from 95 individuals (23 controls, 33 glaucoma suspects, 39 glaucomatous were enrolled. All participants underwent a full ophthalmic examination, followed by SAP, FDT, and mfVEP tests. Results: The area under the curve for mean deviation and pattern standard deviation were 0.756 and 0.761, respectively, for FDT, 0.564 and 0.512 for signal and alpha for interocular mfVEP, and 0.568 and 0.538 for signal and alpha for monocular mfVEP. This difference between monocular and interocular mfVEP was not significant. Conclusion: The FDT matrix was superior to mfVEP in glaucoma detection. The difference between monocular and interocular mfVEP in the diagnosis of glaucoma was not significant. Keywords: standard automated perimetry, electrophysiology, glaucomatous eyes

  2. Inflammatory bowel diseases and the general practitioner’s role in a region of Central Italy

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    Paolo Sossai

    2010-04-01

    Full Text Available Paolo Sossai1,2, Fabio Filippetti3, Ali Ahmad Muselmani4, Giambattista Catalini41Department of Medicine, “Enrico Mattei” Hospital, Viale Europa, I-62024 Matelica, Italy; 2Center of Clinical Research, Department of Experimental Medicine, University of Camerino, Via M Scalzino, 3, I-62032 Camerino, Italy; 3Epidemiological Unit, Marche Region, Via Gentile da Fabriano, 3, I-60125 Ancona, Italy; 4Department of Surgery, General Hospital, Via Caselle, I-62032 Camerino, ItalyBackground: Inflammatory bowel diseases (IBD are a serious burden for both patients and health care providers because of the young age at which they occur and their chronic course.Aim: The purpose of this study was to assess how general practitioners (GPs in the area of Camerino-Matelica, Marche (Central Italy manage their patients with IBD.Materials and methods: Before providing an educational course about IBD to GPs, we administered a simple questionnaire containing 10 multiple-choice questions, allowing for only one possible answer, to GPs in the target area. After the educational course we administered a satisfaction questionnaire and evaluated the hospitalization rates for IBD in the catchment area in the year following the course.Results: In our GP sample, 71.8% indicated that they needed better instruction regarding IBD to enable them to diagnose the conditions given the difficulties posed by nonspecific symptoms and the need to use invasive diagnostic methods such as colonoscopy. Early results after the educational course for GPs indicate a reduced rate of hospitalization for IBD but these data must be confirmed by future research.Conclusions: If specialists and GPs managed IBD patients more carefully, their patients would probably suffer from fewer relapses and would have a better quality of life, which would be likely to mean considerable cost savings for the public health care system and society in general.Keywords: inflammatory bowel disease, Crohn’s disease

  3. Evaluation for yield and quality of oil from seven Ricinus communis varieties.

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    Paola Andrea Rivera-Brenes

    2015-12-01

    Full Text Available The objective of this work was to evaluate the yield and quality of oil from seven Ricinus communis varieties. The morphological properties (height of plant, productive branches, length of clusters, yield of seed, and oil quality. The evaluation was conducted at the Fabio Baudrit Moreno Experimental Station of the University of Costa Rica, Alajuela, Costa Rica, from September 2013 to April 2014. A randomized complete block design with a density of 5000 plants/ha was used for the evaluation. The varieties evaluated were ColBio RH 171,09, ColBio HR 205, ColBio HR 268, ColBioHR 157, 401, and NIC. The parameters evaluated showed significant difference (a<0.05. The seven varieties constituted all medium-sized plants. The average was four productive branches for all varieties. ColBio HR 268, ColBio HR 205, and ColBio HR 171 obtained the longer cluster. Stem diameter showed an average between 3 and 4 cm for the seven treatments. In relation toseed yield, variety NIC had the lowest value (860 kg/ha, while ColBio HR 171, 09, ColBio HR 205, and 268 had the highest yield with an average of 2377kg/ha. Oil content was higher for treatments 401 (88% and ColBio HR 171 (87%. The array 09 showed the highest content of ricinoleic acid (80%, followed by ColBio HR 268 (69% placing both also among the varieties with higer seed yield, but with lower oil content.

  4. Obtención de un híbrido de frijol arbustivo para una cosecha mecanizada

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    Carlos Muñoz Ruiz

    2012-08-01

    Full Text Available En el estudio se evaluaron tres variedades de frijol negro (Brunca, Guaymí y Talamanca, obtenidas en la estación experimental Fabio Baudrit de la Universidad de Costa Rica, y una variedad (Negro Chapingo, obtenida en la Universidad Autónoma de Chapingo, México. Estas variedades no presentaron las características genéticas deseadas para ser utilizadas como donadores y aceptores de polen para obtener un híbrido arbustivo y de floración determinada para su cosecha en forma mecánica en la zona norte del país. Sin embargo, se lograron obtener cinco híbridos F1 entre los cruces realizados, ellos son: BCh, ChT, TCh, BT y TB. Todos ellos presentaron en la F2 características genéticas de porte semiarbustivo (TII y TIII y de floración indeterminada, no compatibles para la obtención de un híbrido adecuado para la cosecha de frijol mecanizada. En este proyecto de investigación se utilizó el método de polinización dirigida o artificial y el cruce simple recíproco entre las variedades participantes y se hicieron 341 polinizaciones entre sí, respectivamente.

  5. Efecto del estado de desecación del rastrojo de arroz en las malezas y en el rendimiento del frijol

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    Franklin Herrera

    2003-01-01

    Full Text Available En la Estación Experimental Agrícola Fabio Baudrit Moreno de la Universidad de Costa Rica, ubicada en el distrito San José, provincia de Alajuela, en la zona de vida Bosque Húmedo Premontano y, entre junio del 2000 y enero del 2001, se realizó un experimento con el propósito de medir el efecto de desecar rastrojo de arroz con glifosato en diferentes periodos antes de la siembra directa del frijol, en el combate de malezas y en el rendimiento del frijol. La aplicación de glifosato sobre los rastrojos de arroz y malezas, desde cinco días antes de la siembra del frijol, hasta dos días después de la siembra pero antes de la emergencia, permitió una adecuada cobertura del suelo por los rastrojos durante el periodo crítico de competencia del frijol, con lo cual se redujo la presencia de malezas y se logró obtener altos rendimientos de frijol sin necesidad de aplicar otros herbicidas. Cuando el periodo de espera después de la aplicación del glifosato fue muy prolongado (30-45 días, la cobertura del suelo por el rastrojo fue pobre, debido a su avanzado estado de descomposición, por lo que hubo mayor presencia de malezas y efectos negativos en la producción de frijol, cuando no hubo control oportuno de esas malezas.

  6. Nanostructured systems containing babassu (Orbignya speciosa oil as a potential alternative therapy for benign prostatic hyperplasia

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    de Sousa VP

    2013-08-01

    Full Text Available Valeria Pereira de Sousa,1 Joanne Crean,2 Vinícius Raphael de Almeida Borges,1 Carlos Rangel Rodrigues,1 Lidia Tajber,2 Fabio Boylan,2 Lucio Mendes Cabral1 1Department of Pharmaceutics, Faculty of Pharmacy, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; 2School of Pharmacy and Pharmaceutical Sciences and Trinity Biomedical Sciences Institute, Trinity College Dublin, Dublin, Ireland Abstract: The oil of babassu tree nuts (Orbignya speciosa is a potential alternative for treatment and prophylaxis of benign prostatic hyperplasia. Improved results can be obtained by drug vectorization to the hyperplastic tissue. The main objective of this work was the preparation and characterization of poly(lactic-co-glycolic acid (PLGA nanoparticle and clay nanosystems containing babassu oil (BBS. BBS was extracted from the kernels of babassu tree nuts and characterized by gas chromatography-mass spectrometry as well as 1H and 13C nuclear magnetic resonance. BBS-clay nanosystems were obtained by adding polyvinylpyrrolidone, Viscogel B8®, and BBS at a 2:1:1 mass ratio and characterized by X-ray diffraction, thermogravimetric analysis, infrared spectroscopy, and laser diffraction. The PLGA-BBS nanoparticles were prepared by the precipitation-solvent evaporation method. Mean diameter, polydispersity, zeta potential, and scanning electron microscopic images of the nanosystems were analyzed. Thermogravimetric analysis showed successful formation of the nanocomposite. PLGA nanoparticles containing BBS were obtained, with a suitable size that was confirmed by scanning electron microscopy. Both nanostructured systems showed active incorporation yields exceeding 90%. The two systems obtained represent a new and potentially efficient therapy for benign prostatic hyperplasia. Keywords: babassu oil, nanocomposite, poly(lactic-co-glycolic acid, nanoparticles, benign prostatic hyperplasia, treatment, nanotechnology

  7. Potential drug–drug interactions in Alzheimer patients with behavioral symptoms

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    Pasqualetti G

    2015-09-01

    Full Text Available Giuseppe Pasqualetti, Sara Tognini, Valeria Calsolaro, Antonio Polini, Fabio Monzani Geriatrics Unit, Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy Abstract: The use of multi drug regimens among the elderly population has increased tremendously over the last decade although the benefits of medications are always accompanied by potential harm, even when prescribed at recommended doses. The elderly populations are particularly at an increased risk of adverse drug reactions considering comorbidity, poly-therapy, physiological changes affecting the pharmacokinetics and pharmacodynamics of many drugs and, in some cases, poor compliance due to cognitive impairment and/or depression. In this setting, drug–drug interaction may represent a serious and even life-threatening clinical condition. Moreover, the inability to distinguish drug-induced symptoms from a definitive medical diagnosis often results in addition of yet another drug to treat the symptoms, which in turn increases drug–drug interactions. Cognitive enhancers, including acetylcholinesterase inhibitors and memantine, are the most widely prescribed agents for Alzheimer’s disease (AD patients. Behavioral and psychological symptoms of dementia, including psychotic symptoms and behavioral disorders, represent noncognitive disturbances frequently observed in AD patients. Antipsychotic drugs are at high risk of adverse events, even at modest doses, and may interfere with the progression of cognitive impairment and interact with several drugs including anti-arrhythmics and acetylcholinesterase inhibitors. Other medications often used in AD patients are represented by anxiolytic, like benzodiazepine, or antidepressant agents. These agents also might interfere with other concomitant drugs through both pharmacokinetic and pharmacodynamic mechanisms. In this review we focus on the most frequent drug–drug interactions, potentially harmful, in AD patients with

  8. Cost-effectiveness evaluation of escitalopram in major depressive disorder in Italy

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    Mencacci C

    2013-02-01

    Full Text Available Claudio Mencacci,1 Guido Di Sciascio,2 Pablo Katz,3 Claudio Ripellino31Ospedale Fatebenefratelli, Milan, Italy; 2Azienda Ospedaliera Universitaria Consorziale Policlinico di Bari, Bari, Italy; 3CSD Medical Research Srl, Milan, ItalyBackground: Depression has a lifetime prevalence of 10%–25% among women and 5%–12% among men. Selective serotonin reuptake inhibitors (SSRIs are the most used and the most cost-effective treatment for long-term major depressive disorder. Since the introduction of generic SSRIs, the costs of branded drugs have been questioned. The objective of this study was to assess the cost-effectiveness (€ per quality-adjusted life year [QALY] of escitalopram (which is still covered by a patent compared with paroxetine, sertraline, and citalopram, the patents for which have expired.Methods: A decision analytic model was adapted from the Swedish Dental and Pharmaceutical Benefits agency model to reflect current clinical practice in the treatment of depression in Italy in collaboration with an expert panel of Italian psychiatrists and health economists. The population comprised patients with a first diagnosis of major depressive disorder and receiving for the first time one of the following SSRIs: escitalopram, sertraline, paroxetine, and citalopram. The time frame used was 12 months. Efficacy and utility data for the original model were validated by our expert panel. Local data were considered for resource utilization and for treatment costs based on the Lombardy region health service perspective. Several scenario simulations, one-way sensitivity analyses, and Monte Carlo simulations were performed to test the robustness of the model.Results: The base case scenario showed that escitalopram had an incremental cost-effectiveness ratio (ICER of €4395 and €1080 per QALY compared with sertraline and paroxetine, respectively. Escitalopram was dominant over citalopram, which was confirmed by most one-way sensitivity analyses. The

  9. The mediating role of cytokine IL-6 on the relationship of FEV1 upon 6-minute walk distance in chronic obstructive pulmonary disease

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    Baldi S

    2014-10-01

    Full Text Available Simonetta Baldi,1 Paul E Jose,2 Claudio Bruschi,1 Gian Domenico Pinna,3 Roberto Maestri,3 Antonella Rezzani,1 Ezio Bellinzona,1 Claudio Fracchia,1 Elena Dacosto,1 Paola Crotti,1 Silvia Montemartini1 1Department of Pneumology, Scientific Institute of Montescano, Salvatore Maugeri Foundation IRCCS, Montescano, Pavia, Italy; 2School of Psychology, Victoria University, Wellington, New Zealand; 3Department of Biomedical Engineering, Scientific Institute of Montescano, Salvatore Maugeri Foundation IRCCS, Montescano, Pavia, ItalyObjectives: To explore the mediating role of protein interleukin-6 (IL-6 on the relationship between forced expiratory volume in 1 second (FEV1 and 6-minute walk distance (6MWD and, further, to determine whether status variables (such as age, sex, and body mass index [BMI] operate as moderators of this mediation relationship.Design: Moderated mediation model.Setting: An inpatient pulmonary rehabilitation center in Italy.Participants: All 153 patients involved in the screening of a randomized controlled clinical trial (ClinicalTrials.gov identifier: NCT01253941 were included in this study. All patients were Global initiative for chronic Obstructive Lung Disease (GOLD stages I–IV and were aged 70.1±9.1 years.Measurements: At run-in phase of the protocol, clinical and functional screening included BMI, fasting plasma levels of protein (IL-6, spirometry, and standardized 6-minute walking test, measured at the start of the respiratory rehabilitation program.Methods: The size of the indirect effect of the initial variable (FEV1 upon the outcome variable (6MWD through the intervening variable (IL-6 was computed and tested for statistical significance. Moderated mediation analyses were subsequently conducted with age, sex, and BMI.Results: FEV1 averaged 53.4%±21.2%, and 6MWD 66.4%±41.3% of predicted. Median protein IL-6 was 6.68 pg/mL (interquartile range: 5.96. A bootstrapped mediation test supported the predicted indirect

  10. La classe T "Economia" nella classificazione bibliografica Bliss Class T "Economics" in Bliss Bibliografic Classification

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    Elisabetta Viti

    2010-12-01

    Full Text Available Partendo da alcune considerazioni generali sul rapporto disciplina-fenomeno all'interno della Classificazione Bibliografica Bliss (2. ed., si offre una panoramica relativa all'architettura di uno specifico dominio disciplinare: l'economia. La difficoltà a sistematizzare questa disciplina come soggetto specifico e la rapida diffusione di acronimi e nuovi termini creati per abbreviazione o per combinazione di parole già esistenti, ha portato a una drastica revisione della struttura della tavola T, Economics & Management of economic enterprise, che è attualmente organizzata in categorie, faccette e sottofaccette, le quali, per formazione di classi composte, seguono un rigoroso ordine di citazione. Il sistema prevede un ordine lineare, una notazione per mantenere l'ordine di elencazione e un indice alfabetico di tutti i termini delle tavole. La BC2 è il solo esempio di architettura classificatoria analitico-sintetica completamente faccettata, aggiornata e coerentemente sviluppata, ma è poco usata al di fuori dell’Inghilterra ed è ancora priva di un'interfaccia web che possa rappresentare tutte le complesse relazioni semantiche del sistema. La sua struttura ha esercitato influenze sull'informatica, testimoniate dal progetto FATKS dell’University College London, che ha studiato l’impiego delle classificazioni analitico-sintetiche come base per l’indicizzazione delle risorse digitali. Sono inoltre in atto alcune sperimentazioni che mostrano le potenzialità di conversione di questa classificazione in formato thesaurus (in particolare della classe dedicata alla musica; ed è oggetto di studio lo sviluppo di un software di generare un thesaurus dagli stessi file di input, usati per la visualizzazione della classificazione e dell’indice alfabetico.L'autrice vuole porgere un sentito ringraziamento ad Alberto Cheti, Claudio Gnoli e Anna Lucarelli per la paziente lettura e i preziosi consigli.Starting from some general thoughts on the

  11. Genital impacts Genital impacts

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    Luiz Felipe G Soares

    2008-04-01

    Full Text Available I propose to analyze three images of genitalia from three different films that do not have sex as their central subject: (1 Lígia’s (Leona Cavalli’s vulva in Claudio Assis’s Amarelo Manga (Brazil, 2002, (2 Stoffer’s (Jens Albinus’s erect penis in Lars von Trier’s The Idiots (Denmark, 1998, and (3 transsexual Dil’s (Jaye Davidson’s penis in Neil Jordan’s The Crying Game (USA, 1992. All three images are explicit and surprising enough to provoke impact, both in diegetic and extra-diagetic spaces. intend to compare the three images and investigate the nature of their impacts, not directly in terms of morality, but in their relation with two theoretical assumptions: (1 the intense way in which, according to Linda Nicholson (1999, so many cultures insist in interpreting bodies and genitalia as still capable of defining gender characters, and (2 the notion of image, not as representation, but as image itself, as “what it is”, or as “the place of every transformation in the universe”, as suggested first by Bergson (2005, and then by Deleuze (1983-5, Rancière (2001 and Agamben (1995. The Deleuzean retard may indicate the way in which genitalia, as image, turn into enigma, in the very passage from nature to culture. The three shots give back to those clear images of genitalia the property they have always had: their character of central pieces in the game of such passage. The contrast between such simple and clear images and all those complex games corresponds to the nature of the impact I want to investigate. film; genitalia; narrative. I propose to analyze three images of genitalia from three different films that do not have sex as their central subject: (1 Lígia’s (Leona Cavalli’s vulva in Claudio Assis’s Amarelo Manga (Brazil, 2002, (2 Stoffer’s (Jens Albinus’s erect penis in Lars von Trier’s The Idiots (Denmark, 1998, and (3 transsexual Dil’s (Jaye Davidson’s penis in Neil Jordan’s The Crying Game (USA

  12. Motivado por cirujanos Motivated by Surgeons

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    Carlos Salazar-Vargas

    2010-12-01

    Full Text Available Comenzaba la década de los 60 y nuestro grupo nerviosamente iniciaba lecciones en los hospitales de San José. En aquellos años, el estudiante de medicina empezaba su contacto con pacientes, por lo menos 1 ó 2 años después de iniciada la carrera. El estudio del ser humano normal que ya habíamos concluido, continuaba con el del enfermo, y más adelante aprenderíamos el tratamiento. La enfermedad descrita en el libro, de pronto se convertía en un enfermo, y es a este quien hoy veíamos, cohibido pero inquisidor, en la cama de un hospital. Los profesores nos enseñaban a interrogar y a examinar a los pacientes, y cada gesto suyo, cada pregunta, cada maniobra, eran celosamente guardados en la memoria de los educandos. Con claridad percibíamos, aun a temprana edad, las diferencias entre los especialistas, y casi de manera involuntaria, cada quien iba tomando partido y escogía su futuro camino. Fue durante esos tempranos años, cuando mi vida se cruzó con la de 7 maravillosas personas y excelentes cirujanos, que marcaron para siempre mi destino y, sin quererlo ellos, me hicieron inclinarme por la cirugía. Dos eran serios y profundamente académicos: el Dr. Manuel Aguilar Bonilla y el Dr. Vesalio Guzmán Calleja; 3, decididos, incansables y muy hábiles: el Dr. Longino Soto Pacheco, el Dr. Claudio Orlich Carranza y el Dr. Carlos Prada Díaz, y 2, abordables, prácticos, joviales y amistosos: el Dr. Fernando Valverde Soley y el Dr. Randall Ferris Iglesias….During the early 60´s our class just started clinical lessons in different hospitals of San Jose. In those years the medical student became in contact with patients 1 or 2 years after initiating his or her career. The study of the normal human being continued with that of the diseased and later on we would learn how to treat our patients. The disease described in our textbooks, suddenly was a reality, a person lying in a hospital bed, shy but inquisitive. Our teachers taught us how to

  13. Vida de Carmen Caamaño Díaz : una voz del exilio interior

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    Mercedes Montero Caldera

    1999-01-01

    Full Text Available Este artículo recoge el testimonio oral de Carmen Caamaño Díaz (Madrid, 1911, quien a través de su memoria hace un recorrido autobiográfico en el que manifiesta la evolución de un compromiso ideológico que la convertiría en sujeto activo del exilio interior durante el régimen franquista. En su etapa universitaria, Carmen fue miembro de la junta Directiva de la FUE (Federación Española de Enseñantes y Secretaria General de la UFEH (Unión Federal de estudiantes Hispanoamericanos desde 1930 a 1931. Licenciada en Filosofía y Letras, trabajó en él Centro de estudios tiistohcos formando parte del equipo de investigación que dirigía Claudio Sáncfiez Albornoz. En 1937 ingresó en el P.C.E, desempeñando, entre otros cargos, el de Gobernadora Civil de Cuenca desde enero a marzo de 1939. Al finalizar la guerra, fue detenida y condenada a prisión. En 1941 trató de reorganizar en la clandestinidad el partido comunista en la provincia de Alicante, siendo nuevamente detenida y condenada a muerte, pena que le sería conmutada por la de cárcel. Depurada profesionalmente y bajo control policial durante varios años, su actividad de oposición al régimen de Franco la llevaría a cabo desde la Asociación de Mujeres Universitarias.This article includes the oral statement of Carmen Caamaño Díaz (Madrid, 1911, who covers her autobiography through her memory, expressing an ideogical compromise evolution through which she would become an active subjet of the inner exile throughout Franco's regime. While being a student at university, she was a member of the Board of Directors of the UFEH (Spanish Teachers Union and General Secretary of the UFEH (Latin American Student Union from 1930 to 1931. With a degree in Arts, she worked at the Centre of Historie Studies taking part within the investigation team conducted by Claudio Sánchez Albornoz. In 1937 she joined the Spanish Communist Party, performing the charge, amongst others, of Civil Governor

  14. Genetic aspects of athletic performance: the African runners phenomenon

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    Vancini RL

    2014-05-01

    Full Text Available Rodrigo Luiz Vancini,1 João Bosco Pesquero,2 Rafael Júlio Fachina,3,4 Marília dos Santos Andrade,1 João Paulo Borin,3 Paulo César Montagner,3 Claudio Andre Barbosa de Lira51Centro de Educação Física e Desportos, Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil; 2Departamento de Biofísica, Universidade Federal de São Paulo, São Paulo, Brazil; 3Departamento de Ciência do Esporte, Faculdade de Educação Física, Universidade Estadual de Campinas, Campinas, Brazil; 4Confederação Brasileira de Basquetebol, Rio de Janeiro, Brazil; 5Setor de Fisiologia Humana e do Exercício, Faculdade de Educação Física, Universidade Federal de Goiás, Goiânia, BrazilAbstract: The current dominance of African runners in long-distance running is an intriguing phenomenon that highlights the close relationship between genetics and physical performance. Many factors in the interesting interaction between genotype and phenotype (eg, high cardiorespiratory fitness, higher hemoglobin concentration, good metabolic efficiency, muscle fiber composition, enzyme profile, diet, altitude training, and psychological aspects have been proposed in the attempt to explain the extraordinary success of these runners. Increasing evidence shows that genetics may be a determining factor in physical and athletic performance. But, could this also be true for African long-distance runners? Based on this question, this brief review proposed the role of genetic factors (mitochondrial deoxyribonucleic acid, the Y chromosome, and the angiotensin-converting enzyme and the alpha-actinin-3 genes in the amazing athletic performance observed in African runners, especially the Kenyans and Ethiopians, despite their environmental constraints.Keywords: genes, genotype, physical exercise, endurance runners

  15. Descriptive epidemiology of injuries in a Brazilian premier league soccer team

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    Fachina RJ

    2013-06-01

    Full Text Available Rafael Júlio de Freitas Guina Fachina,1,2 Marília dos Santos Andrade,3 Fernando Roberto Silva,4 Silas Waszczuk-Junior,4 Paulo César Montagner,1 João Paulo Borin,1 Claudio Andre Barbosa de Lira5 1Departamento de Ciência do Esporte, Faculdade de Educação Física, Universidade Estadual de Campinas (UNICAMP, Campinas, Brazil; 2Confederação Brasileira de Basketball (CBB, Rio de Janeiro, Brazil; 3Departamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, Brazil; 4Grêmio Barueri Futebol LTDA, Barueri, Brazil; 5Setor de Fisiologia Humana e do Exercício, Universidade Federal de Goiás, Câmpus Jataí, Jataí, Brazil Abstract: Soccer, which has a large number of participants, has a high injury incidence that causes both financial and time burdens. Therefore, knowledge about the epidemiology of soccer injuries could allow sports-medicine professionals, such as physicians and physiotherapists, to direct their work in specific preventive programs. Thus, our aim was to conduct an epidemiological survey of injuries sustained by professional soccer players from the same team who participated in the Brazilian championship premier league in 2009. To this end, we evaluated retrospectively player medical records from the team, which included name, date of birth, position, date of injury, mechanism of injury, and type of injury. In the period of study, 95 injuries were recorded: 42 (44.2% were recorded during matches, and 53 (55.8% during the training period. Injuries occurred more frequently in midfielders and strikers. All injuries happened in the lower limb, most of the injuries were muscular, and most occurred as the result of collisions with other athletes. In summary, this study demonstrates that there is a need for greater safety awareness in the training environment. Keywords: injuries, epidemiology, soccer players

  16. Cultura y estética popular: lo híbrido, el gusto y la experiencia

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    Élver Chaparro

    2013-09-01

    Full Text Available Este artículo, enmarcado en el proyecto “Cultura y estética popular en Boyacá” (del grupo de investigación XISQUA de la carrera de diseño gráfico de la Universidad de Boyacá, aborda, en primera instancia, algunas nociones de cultura a partir de la relación pensamiento-lenguaje- comunicación, esbozada en Eco y Díaz de Rada, quienes ofrecen elementos conceptuales para abordar la cultura en el ámbito de la comunicación y las prácticas sociales. Posteriormente se hace un rastreo histórico de la categoría cultura popular, tomando como marco de referencia los trabajos de M. Bajtin y Peter Burke, quienes establecen una correspondencia entre la cultura popular y la relación tensionante entre alta y baja cultura. En el marco de los procesos de modernización e hibridación de la cultura popular se revisa el trabajo del profesor Néstor García Canclini junto con algunas características de la experiencia estética y de las nociones de gusto que particularizan lo popular en los trabajos de Pierre Bourdieu, Claudio Malo y Sergio Martínez Luna. Por último, se reflexiona, a partir de los postulados de Martín-Barbero, sobre cómo los procesos mencionados anteriormente están mediados en la actualidad por la globalización, con las consecuentes influencias sobre los procesos de identidad local.

  17. Class T "Economics" in Bliss Bibliografic Classification

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    Elisabetta Viti

    2010-12-01

    Full Text Available Starting from some general thoughts on the relationship discipline-phenomenon within the Bliss bibliographic classification (2. ed., the article offers an overview of the architecture of a specific field: economics. The difficulties in systematizing the discipline, and the quick diffusion of acronyms and new definitions - created by abbreviation or combination of existing words - lead to a full structural revision of the T entry, Economics & Management of economic enterprise, that at the moment is organized into categories, facets, and subfacets, offering a strict citation order. The system has a linear order, a notation to maintain the listing order, and an alphabetic list of the terms. BC2 is the only example of a classifying analytic-concise architecture fully faceted, updated and coherently developed, even though it is few used outside the United Kingdom, and it still lacks a web interface representing the semantic relations of the system. The influence of BC2 structure on computer science is shown by the FATKS project of the University College London, a project that studies the use of analytic-concise classification systems as the basis for digital resources indexing. Moreover, some ongoing experimentations are demonstrating the potential of this classification to be converted into a thesaurus; in addition, a software for supporting the semi-automatic generation of a thesaurus starting from the input files used for producing the classification and the alphabetic list, is under consideration.The author would thank Alberto Cheti, Claudio Gnoli and Anna Lucarelli for the precise reading and valued suggestions.

  18. An evidence-based review on urate-lowering treatments: implications for optimal treatment of chronic hyperuricemia

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    Bove M

    2017-02-01

    Full Text Available Marilisa Bove, Arrigo Francesco Giuseppe Cicero, Maddalena Veronesi, Claudio Borghi Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy Abstract: Several studies suggest that chronic hyperuricemia, the main precursor of gout, is involved in the pathogenesis of different systemic disorders that affect cardiovascular and renal systems, such as hypertension, obesity, hypercholesterolemia, atherosclerosis, metabolic syndrome, chronic heart failure, and chronic kidney disease. Recent epidemiological evidence has shown an increasing trend in the prevalence of hyperuricemia and gout in the Western world: a number of population-based studies estimate a prevalence of up to 21% for hyperuricemia and 1%–4% for gout. As such, early detection and careful management of this pathological condition is required, starting from lifestyle changes (mainly based on a diet low in red meat, sugars, and alcoholic beverages, with increased intake of vegetables, water, and vitamin C sources, adding specific drugs to lead serum uric acid (SUA levels under the target value of 7 mg/dL. In particular, nonselective and selective XO inhibitors (allopurinol, oxypurinol, febuxostat reduce SUA levels and the overproduction of reactive oxygen species, mainly related to XO overactivity that often causes inflammatory damage to the vascular endothelium. The effect of lowering SUA levels via XO inhibition includes an attenuation of oxidative stress and related endothelial dysfunction that largely contribute to the pathophysiology of metabolic syndrome and cardiovascular diseases. Therefore, the inhibition of XO overactivation seems to be an excellent therapeutic option to limit the harmful effects of excess UA and reactive oxygen species. In conclusion, rapid diagnosis and correct therapy for hyperuricemia may also improve the prevention and/or treatment of serious and multifactorial diseases. The available evidence supports the importance of

  19. Comercio e intercambio de cerámicas finas en la Bética (ss. I-II d. C.: reflexiones generales en torno a la economía altoimperial al hilo del análisis del ejemplo isturgitano

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    Pablo RUIZ MONTES

    2013-06-01

    Full Text Available El análisis de un caso concreto, el de la comercialización de la producción de cerámicas finas de los talleres alfareros de Los Villares de Andújar (Jaén, antigua Isturgi, ofrece la oportunidad para reflexionar sobre diversos aspectos relativos al intercambio y circulación de este tipo de bienes coincidiendo con los años de mayor bonanza económica y social en la Bética; el análisis de la naturaleza de la economía romana, de las formas y alcance que adquiere el comercio en cuestión (distribución local-regional y a larga distancia y su caracterización esencial, así como otros elementos colaterales al fenómeno (valor, gusto, consumidores..., han centrado nuestra atención. Todo ello permite dibujar una situación de excepcional dinamismo económico del que la producción y comercio de vajillas cerámicas locales, en especial la sigillata, es parte, pero también consecuencia. El proceso, intensificado desde Claudio I gracias al desarrollo de la red de comunicaciones y los transportes, la mayor demanda de bienes y un moderado crecimiento demográfico, propicia la aparición de nuevos estándares en la producción de cerámicas finas locales béticas, hasta entonces dominada aún por las tradiciones autóctonas y la desestructurada producción de cerámicas tipo Peñaflor.

  20. Moradas de la razón sensible

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    María Eugenia Boito

    2012-03-01

    Full Text Available “Jirones de piel, ágape insumiso” establece relaciones entre la reflexión epistemológica, la estética y la normatividad en catorce apartados que –como jirones– pueden interpretarse como “pequeñas porciones de un todo”; fragmentos de telas (tramas discursivas que recorren y se detienen en la interrogación de la compleja madeja que reúne los tópicos antes referidos. Pero “jirón” tiene otro significado en el campo de la heráldica que en mi lectura, está asociada a las figuras que produce el texto: “jirón” es una forma triangular que desde el borde del escudo, llega hasta el centro o corazón de este. Claudio Martyniuk afirma “no ensancha escribir, no ensancha leer, apenas salva del extravío y de la tristeza vacías”. Sin embargo los jirones de su escritura ensayística (el ensayo como género que pretende “un despliegue que tense los entumecidos polos de la sensibilidad y el pensamiento” se orientan a proteger como escudo –pero a la vez interrogar– lo que se encuentra el corazón de los recorridos de la obra: los ejercicios de violencia cotidiana sobre nuestra piel. Por esto además de salvar del extravío y de la tristeza, la escritura de Martyniuk señala –y asila, da regazo– a la piel como instancia de expresión de nuestra sensibilidad.

  1. Bismuth oxide aqueous colloidal nanoparticles inhibit Candida albicans growth and biofilm formation

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    Hernandez-Delgadillo R

    2013-04-01

    Full Text Available Rene Hernandez-Delgadillo,1 Donaji Velasco-Arias,3 Juan Jose Martinez-Sanmiguel,2 David Diaz,3 Inti Zumeta-Dube,3 Katiushka Arevalo-Niño,1 Claudio Cabral-Romero2 1Facultad de Ciencias Biológicas, Instituto de Biotecnologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Mexico; 2Facultad de Odontología, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, México; 3Facultad de Quimica, Universidad Nacional Autonoma de Mexico, UNAM, Distrito Federal, México Abstract: Multiresistance among microorganisms to common antimicrobials has become one of the most significant concerns in modern medicine. Nanomaterials are a new alternative to successfully treat the multiresistant microorganisms. Nanostructured materials are used in many fields, including biological sciences and medicine. Recently, it was demonstrated that the bactericidal activity of zero-valent bismuth colloidal nanoparticles inhibited the growth of Streptococcus mutans; however the antimycotic potential of bismuth nanostructured derivatives has not yet been studied. The main objective of this investigation was to analyze the fungicidal activity of bismuth oxide nanoparticles against Candida albicans, and their antibiofilm capabilities. Our results showed that aqueous colloidal bismuth oxide nanoparticles displayed antimicrobial activity against C. albicans growth (reducing colony size by 85% and a complete inhibition of biofilm formation. These results are better than those obtained with chlorhexidine, nystatin, and terbinafine, the most effective oral antiseptic and commercial antifungal agents. In this work, we also compared the antimycotic activities of bulk bismuth oxide and bismuth nitrate, the precursor metallic salt. These results suggest that bismuth oxide colloidal nanoparticles could be a very interesting candidate as a fungicidal agent to be incorporated into an oral antiseptic. Additionally, we determined the minimum inhibitory concentration for the synthesized

  2. Chronic fluoxetine treatment increases daytime melatonin synthesis in the rodent

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    Gillian W Reierson

    2009-09-01

    Full Text Available Gillian W Reierson, Claudio A Mastronardi, Julio Licinio, Ma-Li WongCenter on Pharmacogenomics, Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL, USAAbstract: Circadian rhythm disturbances can occur as part of the clinical symptoms of major depressive disorder and have been found to resolve with antidepressant therapy. The pineal gland is relevant to circadian rhythms as it secretes the hormone melatonin following activation of the cyclic adenosine monophosphate (cAMP signaling cascade and of arylalkylamine N-acetyltransferase (AA-NAT, the rate-limiting enzyme for its synthesis. Cyclic AMP is synthesized by adenylate cyclases (AC and degraded by phosphodiesterases (PDEs. Little is known about the contribution of the PDE system to antidepressant-induced alterations in pineal cAMP signaling and melatonin synthesis. In the present study we used enzyme immunoassay to measure plasma melatonin levels and pineal cAMP levels and as well as quantitative real-time polymerase chain reaction to measure pineal expression of PDE, AC, and AA-NAT genes in rats chronically treated with the prototypic antidepressant fluoxetine. We found elevated melatonin synthesis with increased pineal AA-NAT gene expression and daytime plasma melatonin levels and downregulated cAMP signaling with increased PDE and unchanged AC pineal gene expression, and decreased content of pineal cAMP. We conclude that chronic fluoxetine treatment increases daytime plasma melatonin and pineal AA-NAT gene expression despite downregulated pineal cAMP signaling in the rodent.Keywords: antidepressant, melatonin, pineal, nucleotides, cyclic, phosphodiesterase, rat

  3. Profile of evolocumab and its potential in the treatment of hyperlipidemia

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    Cicero AF

    2015-06-01

    Full Text Available Arrigo FG Cicero, Alessandro Colletti, Claudio Borghi Medical and Surgical Sciences Department, University of Bologna, Bologna, Italy Abstract: Despite the proven efficacy of statins, they often fail to achieve low-density lipoprotein (LDL cholesterol goals, especially in high-risk patients. Moreover, a large number of subjects cannot tolerate statins or full doses of these drugs, in particular patients with familial hypercholesterolemia. Thus, there is a need for additional effective LDL cholesterol-reducing agents. Evolocumab (AMG145 is a monoclonal antibody inhibiting proprotein convertase subtilisin/kexin type 9 that binds to the liver LDL receptor and prevents it from normal recycling by targeting it for degradation. Phase I, II, and III trials revealed that, on subcutaneous injection, either alone or in combination with statins, evolocumab is able to reduce high LDL cholesterol levels from 54% to 80%, apolipoprotein B100 from 31% to 61%, and lipoprotein(a from 12% to 36%, in a dose-dependent manner. The incidence of side effects seems to be low and mainly limited to nasopharyngitis, injection site pain, arthralgia, and back pain. Evolocumab is an innovative powerful lipid-lowering drug, additive to statins and/or ezetimibe, with a large therapeutic range associated with a low rate of mild adverse events. If the available data are confirmed in long-term trials with strong outcome measures, evolocumab will become an essential tool in the treatment of a large number of high-risk patients, such as those affected by familial hypercholesterolemia, those who are unable to tolerate an efficacious statin dosage, and those at very high cardiovascular risk and unable to achieve their target LDL cholesterol levels with currently available lipid-lowering therapies. Keywords: hypercholesterolemia, lipid-lowering drugs, proprotein convertase subtilisin/kexin type 9, AMG145

  4. Ultrasound-mediated oncolytic virus delivery and uptake for increased therapeutic efficacy: state of art

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    Nande R

    2015-11-01

    Full Text Available Rounak Nande,1 Candace M Howard,2 Pier Paolo Claudio,3,4 1Department of Biochemistry and Microbiology, Marshall University School of Medicine, Huntington, WV, 2Department of Radiology, University of Mississippi Medical Center, Jackson, MS, 3Department of BioMolecular Sciences and National Center for Natural Products Research, School of Pharmacy, University of Mississippi, MS, 4Department of Radiation Oncology, University of Mississippi Medical Center, Jackson, MS, USA Abstract: The field of ultrasound (US has changed significantly from medical imaging and diagnosis to treatment strategies. US contrast agents or microbubbles (MB are currently being used as potential carriers for chemodrugs, small molecules, nucleic acids, small interfering ribonucleic acid, proteins, adenoviruses, and oncolytic viruses. Oncolytic viruses can selectively replicate within and destroy a cancer cell, thus making them a powerful therapeutic in treating late-stage or metastatic cancer. These viruses have been shown to have robust activity in clinical trials when injected directly into tumor nodules. However limitations in oncolytic virus’ effectiveness and its delivery approach have warranted exploration of ultrasound-mediated delivery. Gene therapy bearing adenoviruses or oncolytic viruses can be coupled with MBs and injected intravenously. Following application of US energy to the target region, the MBs cavitate, and the resulting shock wave enhances drug, gene, or adenovirus uptake. Though the underlying mechanism is yet to be fully understood, there is evidence to suggest that mechanical pore formation of cellular membranes allows for the temporary uptake of drugs. This delivery method circumvents the limitations due to stimulation of the immune system that prevented intravenous administration of viruses. This review provides insight into this intriguing new frontier on the delivery of oncolytic viruses to tumor sites.Keywords: microbubbles, ultrasound

  5. Mithramycin encapsulated in polymeric micelles by microfluidic technology as novel therapeutic protocol for beta-thalassemia

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    Capretto L

    2012-01-01

    Full Text Available Lorenzo Capretto1, Stefania Mazzitelli2, Eleonora Brognara2, Ilaria Lampronti2, Dario Carugo1, Martyn Hill1, Xunli Zhang1, Roberto Gambari2, Claudio Nastruzzi31Engineering Sciences, University of Southampton, Southampton, UK; 2Department of Biochemistry and Molecular Biology, 3Department of Pharmaceutical Sciences, University of Ferrara, Ferrara, ItalyAbstract: This report shows that the DNA-binding drug, mithramycin, can be efficiently encapsulated in polymeric micelles (PM-MTH, based on Pluronic® block copolymers, by a new microfluidic approach. The effect of different production parameters has been investigated for their effect on PM-MTH characteristics. The compared analysis of PM-MTH produced by microfluidic and conventional bulk mixing procedures revealed that microfluidics provides a useful platform for the production of PM-MTH with improved controllability, reproducibility, smaller size, and polydispersity. Finally, an investigation of the effects of PM-MTH, produced by microfluidic and conventional bulk mixing procedures, on the erythroid differentiation of both human erythroleukemia and human erythroid precursor cells is reported. It is demonstrated that PM-MTH exhibited a slightly lower toxicity and more pronounced differentiative activity when compared to the free drug. In addition, PM-MTH were able to upregulate preferentially γ-globin messenger ribonucleic acid production and to increase fetal hemoglobin (HbF accumulation, the percentage of HbF-containing cells, and their HbF content without stimulating α-globin gene expression, which is responsible for the clinical symptoms of ß-thalassemia. These results represent an important first step toward a potential clinical application, since an increase in HbF could alleviate the symptoms underlying ß-thalassemia and sickle cell anemia. In conclusion, this report suggests that PM-MTH produced by microfluidic approach warrants further evaluation as a potential therapeutic protocol

  6. Zerovalent bismuth nanoparticles inhibit Streptococcus mutans growth and formation of biofilm

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    Hernandez-Delgadillo R

    2012-04-01

    Full Text Available Rene Hernandez-Delgadillo1, Donaji Velasco-Arias2, David Diaz2, Katiushka Arevalo-Niño1, Marianela Garza-Enriquez1, Myriam A De la Garza-Ramos1, Claudio Cabral-Romero11Instituto de Biotecnologia, Centro de Investigacion y Desarrollo en Ciencias de la Salud, CIDICS, Facultad de Odontologia, Universidad Autonoma de Nuevo Leon, UANL, Monterrey, Nuevo Leon, 2Facultad de Quimica, Universidad Nacional Autonoma de Mexico, Distrito Federal, MexicoBackground and methods: Despite continuous efforts, the increasing prevalence of resistance among pathogenic bacteria to common antibiotics has become one of the most significant concerns in modern medicine. Nanostructured materials are used in many fields, including biological sciences and medicine. While some bismuth derivatives has been used in medicine to treat vomiting, nausea, diarrhea, and stomach pain, the biocidal activity of zerovalent bismuth nanoparticles has not yet been studied. The objective of this investigation was to analyze the antimicrobial activity of bismuth nanoparticles against oral bacteria and their antibiofilm capabilities.Results: Our results showed that stable colloidal bismuth nanoparticles had 69% antimicrobial activity against Streptococcus mutans growth and achieved complete inhibition of biofilm formation. These results are similar to those obtained with chlorhexidine, the most commonly used oral antiseptic agent. The minimal inhibitory concentration of bismuth nanoparticles that interfered with S. mutans growth was 0.5 mM.Conclusion: These results suggest that zerovalent bismuth nanoparticles could be an interesting antimicrobial agent to be incorporated into an oral antiseptic preparation.Keywords: zerovalent bismuth nanoparticles, antimicrobial agent, biofilm, Streptococcus mutans

  7. Problem-solving strategies in psychiatry: differences between experts and novices in diagnostic accuracy and reasoning

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    Gabriel A

    2013-01-01

    Full Text Available Adel Gabriel,1,2 Claudio Violato21Departments of Psychiatry, University of Calgary, Calgary; 2Medical Education, Community Health Sciences, University of Calgary Calgary, CanadaBackground: The purpose of this study was to examine and compare diagnostic success and its relationship with the diagnostic reasoning process between novices and experts in psychiatry.Methods: Nine volunteers, comprising five expert psychiatrists and four clinical clerks, completed a think-aloud protocol while attempting to make a DSM-IV (Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition diagnosis of a selected case with both Axis I and Axis III diagnoses.Results: Expert psychiatrists made significantly more successful diagnoses for both the primary psychiatric and medical diagnoses than clinical clerks. Expert psychiatrists also gave fewer differential options. Analyzing the think-aloud protocols, expert psychiatrists were much more organized, made fewer mistakes, and utilized significantly less time to access their knowledge than clinical clerks. Both novices and experts seemed to use the hypothetic-deductive and scheme-inductive approaches to diagnosis. However, experts utilized hypothetic-deductive approaches significantly more often than novices.Conclusion: The hypothetic-deductive diagnostic strategy was utilized more than the scheme-inductive approach by both expert psychiatrists and clinical clerks. However, a specific relationship between diagnostic reasoning and diagnostic success could not be identified in this small pilot study. The author recommends a larger study that would include a detailed analysis of the think-aloud protocols.Keywords: diagnostic reasoning, knowledge structure, psychiatric diagnosis, hypothetic-deductive, scheme-inductive

  8. Cystoid macular edema after cataract surgery in a patient with previous severe iritis following argon laser peripheral iridoplasty

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    Bagnis A

    2011-04-01

    Full Text Available Alessandro Bagnis1, Sergio Claudio Saccà2, Michele Iester1, Carlo Enrico Traverso11Centro di Ricerca Clinica e Laboratorio per il Glaucoma e la Cornea, Clinica Oculistica Di NOG, University of Genova, 2Division of Ophthalmology, St. Martino Hospital, Genova, ItalyAbstract: This report describes a patient who had exaggerated responses to different inflammatory stimuli represented by laser and incisional surgery, respectively. These separate episodes should have a common link represented by a genetic predisposition to abnormal release of proinflammatory mediators within the eye. This 51-year old Hispanic woman showed a narrow iridocorneal angle with plateau iris configuration. Nd-YAG laser peripheral iridotomy was successfully performed to both eyes. No substantial changes in the iridotrabecular angle occurred despite patent iridotomies, thus confirming the diagnosis of plateau iris configuration. Argon laser iridoplasty was then performed to the right eye, while the left eye was scheduled for a later session. A severe inflammatory reaction within the anterior chamber developed after tapering of a one-week course of steroid therapy. Phacoemulsification of the lens was performed some months later when no signs of inflammation were detectable; no intraoperative complications occurred during surgery and an intraocular lens was placed. Cystoid macular edema developed four weeks after surgery despite no apparent risk factors, and resolved completely after anti-inflammatory medical therapy. Based on this case report, the unusual occurrence of severe iritis after laser treatment should be regarded as a risk factor for any other incisional or nonincisional procedures because it might indicate that the patient's ocular tissues are prone to release of abnormally elevated proinflammatory mediators. Although further studies are needed to confirm this predisposition, prophylactic adjunctive topical nonsteroidal anti-inflammatory drug administration after

  9. New advances in the treatment of generalized lipodystrophy: role of metreleptin

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    Rodriguez AJ

    2015-09-01

    Full Text Available Alexander J Rodriguez,1 Claudio A Mastronardi,2 Gilberto J Paz-Filho2 1Department of Medicine, Monash Medical Centre, Clayton, VIC, 2Department of Genome Sciences, The John Curtin School of Medical Research, The Australian National University, Canberra, ACT, AustraliaAbstract: Recombinant methionyl human leptin or metreleptin is a synthetic leptin analog that has been trialed in patients with leptin-deficient conditions, such as leptin deficiency due to mutations in the leptin gene, hypothalamic amenorrhea, and lipodystrophy syndromes. These syndromes are characterized by partial or complete absence of adipose tissue and hormones derived from adipose tissue, most importantly leptin. Patients deficient in leptin exhibit a number of severe metabolic abnormalities such as hyperglycemia, hypertriglyceridemia, and hepatic steatosis, which can progress to diabetes mellitus, acute pancreatitis, and hepatic cirrhosis, respectively. For the management of these abnormalities, multiple therapies are usually required, and advanced stages may be progressively difficult to treat. Following many successful trials, the US Food and Drug Administration approved metreleptin for the treatment of non-HIV-related forms of generalized lipodystrophy. Leptin replacement therapy with metreleptin has, in many cases, reversed these metabolic complications, with improvements in glucose-insulin-lipid homeostasis, and regression of fatty liver disease. Besides being effective, a daily subcutaneous administration of metreleptin is generally safe, but the causal association between metreleptin and immune complications (such as lymphoma is still unclear. Moreover, further investigation is needed to elucidate mechanisms by which metreleptin leads to the development of anti-leptin antibodies. Herein, we review clinical aspects of generalized lipodystrophy and the pharmacological profile of metreleptin. Further, we examine studies that assessed the safety and efficacy of

  10. Clinical experience and critical evaluation of the role of everolimus in advanced renal cell carcinoma

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    Sun M

    2011-04-01

    Full Text Available Maxine Sun1, Firas Abdollah2, Jan Schmitges1, Claudio Jeldres1, Shahrokh F Shariat3, Paul Perrotte4, Pierre I Karakiewicz1,4 1Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada; 2Department of Urology, Vita Salute San Raffaele University, Milan, Italy; 3Department of Urology, Weill Medical College of Cornell University, New York, NY, USA; 4Department of Urology, University of Montreal Health Center, Montreal, CanadaAbstract: The efficacy of sequential everolimus, an orally administered inhibitor of mammalian target of rapamycin (mTOR, was proven in a placebo-controlled phase III study, where median progression-free survival was 4.9 vs 1.9 months for placebo (hazard ratio: 0.33, P < 0.001. Placebo crossovers (80% contaminated overall survival data. Adverse event discontinuation rate was of only 10% and health-adjusted quality-of-life was sustained. These data represent the first placebo-controlled evidence of efficacy for a seque ntially used targeted agent. Everolimus resulted in the strongest hazard ratio ever recorded for progression-free survival, despite it being tested in a population with the most aggressive natural history ever recorded in all available phase III metastatic renal cell carcinoma trials. Everolimus use after exclusively one prior antivascular endothelial growth factor f ailure resulted in an even longer progression-free survival time (5.4 months than in the entire population (4.9 months. These benefits should also be considered in the light of sustained and unimpaired health-related quality of life. Use in first line other than second or subsequent lines remains to be validated.Keywords: everolimus, metastatic renal cell carcinoma, targeted therapy, sequential therapy, mTOR

  11. ETNOGRAFIA - As paneleiras de Goiabeiras e a arte de fazer panela de barro: Ensaio etnográfico sobre a cultura do barro

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    Braz Campos Nicole

    2012-07-01

    Full Text Available Reconhecida pelo Instituto do Patrimônio Histórico e Artístico Nacional (IPHAN, 2006 como um Patrimônio Cultural Imaterial do Brasil, a “arte de fazer panela de barro” representa uma das principais referências culturais do Espírito Santo. Objeto de pesquisas e artigos científicos (Perota, 1997; Dias, 2006; Rodrigues, 2012; entre outros, as Paneleiras de Goiabeiras Velha destacam-se pelo modo sui generis de produção das peças cerâmicas, assegurando para si a autenticidade da panela de barro capixaba. Tento em vista sua relevância, este ensaio descreverá o processo de confecção das panelas de barro e os significados que perpassam esse processo. Ademais, analisará a interconexão cultural entre a cultura do barro e a lógica capitalista, buscando entender sua dinâmica cultural. O presente trabalho resulta de pesquisas realizadas entre 2009 e 2011, com as 32 Paneleiras associadas e que trabalham no galpão3 da Associação das Paneleiras de Goiabeiras Velha (APG, Vitória, Espírito Santo. A partir de 2011, as pesquisas foram revisadas e organizadas no Núcleo de Estudos e Pesquisas Indiciárias da Universidade Federal do Espírito Santo (NEI/UFES, sob a orientação do professor Claudio Marcio Coelho. Trata-se de um estudo qualitativo, tendo como instrumentos de coleta de dados: entrevistas, histórias de vida, questionários semiestruturados, pesquisa documental, pesquisa bibliográfica e observação direta.Palavras-Chave: paneleiras; Goiabeiras Velha; panela de barro; interpretativismo cultural.

  12. Agronomic traits and deoxynivalenol contamination of two tetraploid wheat species (Triticum turgidum spp. durum, Triticum turgidum spp. turanicum grown strictly under low input conditions

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    Giovanni Dinelli

    2014-09-01

    Full Text Available An evaluation of the agronomic performance of two tetraploid wheat varieties (Triticum turgidum spp. durum, Claudio; Triticum turgidum spp. turanicum, Kamut® grown strictly under low input conditions was carried out over three consecutive cropping years. The study reported grain yield values ranging from 1.8 to 2.6 t ha-1. Productivity showed to be primarily affected by environmental conditions, while no differences were observed between the two genotypes. The study of the yield components highlighted that the durum wheat variety had a higher plant density than Kamut®, but this discrepancy was offset by a greater number of kernels per spike and the kernel weight of khorasan wheat. The investigated wheat genotypes were also analysed to assess the mycotoxin (DON levels of wholegrain semolina and the efficiency of cleaning treatments to reduce contamination. Results showed that both wheat varieties had a good hygienic and sanitary quality with a DON content ranging from 0.35 to 1.31 mg kg-1, which was lower than the maximum acceptable level set by the European regulation at 1.75 mg kg-1. In addition, our research work investigated the effects of premilling cleaning procedures, such as water washing and brushing, on mycotoxin levels, which yielded interesting results in terms of decontamination efficiency. These methods were particularly efficient with Kamut® semolina (46-93% DON reduction, suggesting that mycotoxins accumulate in this variety at more superficial levels than in the durum wheat variety. On the whole, our study provided additional knowledge on the traits to be further improved to respond to low input requirements and to enhance the potential adaptability of wheat genotypes to organic agriculture. Our results emphasized the need to develop wheat varieties that can provide adequate performance without high levels of nitrogen inputs by selecting specific traits, such as kernel weight, spike length and kernel/spike. This may help

  13. Motivado por cirujanos

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    Carlos Salazar-Vargas

    2010-12-01

    Full Text Available Comenzaba la década de los 60 y nuestro grupo nerviosamente iniciaba lecciones en los hospitales de San José. En aquellos años, el estudiante de medicina empezaba su contacto con pacientes, por lo menos 1 ó 2 años después de iniciada la carrera. El estudio del ser humano normal que ya habíamos concluido, continuaba con el del enfermo, y más adelante aprenderíamos el tratamiento. La enfermedad descrita en el libro, de pronto se convertía en un enfermo, y es a este quien hoy veíamos, cohibido pero inquisidor, en la cama de un hospital. Los profesores nos enseñaban a interrogar y a examinar a los pacientes, y cada gesto suyo, cada pregunta, cada maniobra, eran celosamente guardados en la memoria de los educandos. Con claridad percibíamos, aun a temprana edad, las diferencias entre los especialistas, y casi de manera involuntaria, cada quien iba tomando partido y escogía su futuro camino. Fue durante esos tempranos años, cuando mi vida se cruzó con la de 7 maravillosas personas y excelentes cirujanos, que marcaron para siempre mi destino y, sin quererlo ellos, me hicieron inclinarme por la cirugía. Dos eran serios y profundamente académicos: el Dr. Manuel Aguilar Bonilla y el Dr. Vesalio Guzmán Calleja; 3, decididos, incansables y muy hábiles: el Dr. Longino Soto Pacheco, el Dr. Claudio Orlich Carranza y el Dr. Carlos Prada Díaz, y 2, abordables, prácticos, joviales y amistosos: el Dr. Fernando Valverde Soley y el Dr. Randall Ferris Iglesias….

  14. A study of periodic and aperiodic ferromagnetic antidot lattices

    Science.gov (United States)

    Bhat, Vinayak S.

    This thesis reports our study of the effect of domain wall pinning by ferromagnetic (FM) metamaterials [1] in the form of periodic antidot lattices (ADL) on spin wave spectra in the reversible regime. This study was then extended to artificial quasicrystals in the form of Penrose P2 tilings (P2T). Our DC magnetization study of these metamaterials showed reproducible and temperature dependent knee anomalies in the hysteretic regime that are due to the isolated switching of the FM segments. Our dumbbell model analysis [2] of simulated magnetization maps indicates that FM switching in P2T is nonstochastic . We have also acquired the first direct, two-dimensional images of the magnetization of Permalloy films patterned into P2T using scanning electron microscopy with polarization analysis (SEMPA). Our SEMPA images demonstrate P2T behave as geometrically frustrated networks of narrow ferromagnetic film segments having near-uniform, bipolar (Ising-like) magnetization, similar to artificial spin ices (ASI). We find the unique aperiodic translational symmetry and diverse vertex coordination of multiply-connected P2T induce a more complex spin-ice behavior driven by exchange interactions in vertex domain walls, which differs markedly from the behavior of disconnected ASI governed only by dipolar interactions. Keywords: Ferromagnetic Antidot Lattices, Metamaterials, Ferromagnetic Resonance, Artificial Quasicrystal, Artificial Spin Ice. [1] VV Kruglyak et al. "Magnonic metamaterials". In: Metamaterial, edited by X.-Y. Jiang (InTech, 2012) (2012). [2] Claudio Castelnovo, Roderich Moessner, and Shivaji L Sondhi. "Magnetic monopoles in spin ice". In: Nature 451.7174 (2008), pp. 42--45.

  15. High-throughput SNP discovery and genotyping in durum wheat (Triticum durum Desf.).

    Science.gov (United States)

    Trebbi, Daniele; Maccaferri, Marco; de Heer, Peter; Sørensen, Anker; Giuliani, Silvia; Salvi, Silvio; Sanguineti, Maria Corinna; Massi, Andrea; van der Vossen, Edwin Andries Gerard; Tuberosa, Roberto

    2011-08-01

    We describe the application of complexity reduction of polymorphic sequences (CRoPS(®)) technology for the discovery of SNP markers in tetraploid durum wheat (Triticum durum Desf.). A next-generation sequencing experiment was carried out on reduced representation libraries obtained from four durum cultivars. SNP validation and minor allele frequency (MAF) estimate were carried out on a panel of 12 cultivars, and the feasibility of genotyping these SNPs in segregating populations was tested using the Illumina Golden Gate (GG) technology. A total of 2,659 SNPs were identified on 1,206 consensus sequences. Among the 768 SNPs that were chosen irrespective of their genomic repetitiveness level and assayed on the Illumina BeadExpress genotyping system, 275 (35.8%) SNPs matched the expected genotypes observed in the SNP discovery phase. MAF data indicated that the overall SNP informativeness was high: a total of 196 (71.3%) SNPs had MAF >0.2, of which 76 (27.6%) showed MAF >0.4. Of these SNPs, 157 were mapped in one of two mapping populations (Meridiano × Claudio and Colosseo × Lloyd) and integrated into a common genetic map. Despite the relatively low genotyping efficiency of the GG assay, the validated CRoPS-derived SNPs showed valuable features for genomics and breeding applications such as a uniform distribution across the wheat genome, a prevailing single-locus codominant nature and a high polymorphism. Here, we report a new set of 275 highly robust genome-wide Triticum SNPs that are readily available for breeding purposes.

  16. El Templum Divi Claudii. Decoración y elementos arquitectónicos para su reconstrucción

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    Domingo, Javier Á.

    2011-12-01

    Full Text Available To date, little data of the Templum Divi Claudii has been available. It was dedicated by Agrippina to her deified dead husband. Nothing but a schematic drawing of the FUR of the temple, done in the 16th century, as well as a few fragments of the same marble floor, belonging to the temenos. However, thanks to the discovery of some decorative architectural elements of the temple, we can finally make a volumetric reconstruction of the monument and find out how its construction fully followed the gigantic architectural tradition started by Augustus with the temple of Mars Ultor. Its measurements, virtually identical to those of this temple, also offer the possibility of linking the emperors Claudius and Vespasian, the restorer of the Claudianum, to Augustus.Hasta el momento disponíamos de pocos datos del Templum Divi Claudii, dedicado por Agripina a su difunto esposo divinizado; apenas un esquemático dibujo realizado en el s. XVI de la pieza de la FUR correspondiente al templo, así como algunos escasos fragmentos de esta misma planta marmórea correspondientes al temenos. Sin embargo, gracias a la localización de algunos elementos de la decoración arquitectónica del templo, ahora, finalmente, podemos realizar una reconstrucción volumétrica del edificio y descubrir cómo su construcción participó plenamente de la tradición de la arquitectura gigantesca iniciada por Augusto con el templo de Mars Ultor. Sus medidas, prácticamente idénticas a las de este templo, ofrecen además la posibilidad de vincular a los emperadores Claudio y Vespasiano, restaurador del Claudianum, con Augusto.

  17. In vivo anticancer evaluation of the hyperthermic efficacy of anti-human epidermal growth factor receptor-targeted PEG-based nanocarrier containing magnetic nanoparticles

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    Baldi G

    2014-06-01

    Full Text Available Giovanni Baldi,1 Costanza Ravagli,1 Filippo Mazzantini,1 George Loudos,2 Jaume Adan,3 Marc Masa,3 Dimitrios Psimadas,2 Eirini A Fragogeorgi,2 Erica Locatelli,4 Claudia Innocenti,5,6 Claudio Sangregorio,5,7 Mauro Comes Franchini4 1CERICOL, Sovigliana-Vinci, Italy; 2Technological Educational Institute of Athens, Athens, Greece; 3Leitat Technological Center, Barcelona, Spain; 4Department of Industrial Chemistry Toso Montanari, University of Bologna, Bologna, 5Consorzio Interuniversitario Nazionale per la Scienza e Tecnologia dei Materiali (INSTM, 6Dipartimento di Chimica U Schiff, Università di Firenze, Firenze, 7Centro Nazionale delle Ricerche (ICCOM – CNR, Firenze, Italy Abstract: Polymeric nanoparticles with targeting moieties containing magnetic nanoparticles as theranostic agents have considerable potential for the treatment of cancer. Here we report the chemical synthesis and characterization of a poly(D,L-lactide-co-glycolide-b-poly(ethylene glycol-based nanocarrier containing iron oxide nanoparticles and human epithelial growth factor receptor on the outer shell. The nanocarrier was also radiolabeled with 99mTc and tested as a theranostic nanomedicine, ie, it was investigated for both its diagnostic ability in vivo and its therapeutic hyperthermic effects in a standard A431 human tumor cell line. Following radiolabeling with 99mTc, the biodistribution and therapeutic hyperthermic effects of the nanosystem were studied noninvasively in vivo in tumor-bearing mice. A substantial decrease in tumor size correlated with an increase in both nanoparticle concentration and local temperature was achieved, confirming the possibility of using this multifunctional nanosystem as a therapeutic tool for epidermoid carcinoma. Keywords: magnetic nanoparticles, polymeric nanocarriers, skin cancer, hyperthermia, single-photon emission computed tomography, imaging

  18. Oraciones en plata: estudio de la obra inédita de Jacobo Pecul Montenegro

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    Canedo Barreiro, María

    2015-12-01

    Full Text Available The purpose of this research is the study and attribution of new pieces to Jacobo Pecul Monte negro (1753-1817 a silversmith from Santiago de Compostela. His production reflects an aesthetic clearly influenced by French forms which he learnt from his father Claudio Pecul. But also Galician artists´ work, such as Ferreiro or Simón Rodríguez, had an impact on Montenegro's own creations. Twenty four new pieces have been selected from parish crosses, holy chalices, ciboriums, censers, “navetas” and monstrances, which are referenced in Pecul's manuscript “Libro de Caja”. They were extracted by Couselo Bouzas in his Galicia Artística, and catalogued in the Diocesan Archive of the Catholic Church. These pieces have been studied and attributed to Jacobo Pecul Montenegro by the guidelines set by José Manuel López Vázquez, who has studied the work of this silversmith in depth. This article attempts to make a brief study of both the author and the silversmithing typologies in the shift from the baroque style to the neoclassical style. And at the same time this study also aims to draw attention to Galician silversmithing, which is a patrimony of our popular imagery, and more often than not highly neglected.La presente investigación tiene como objetivo el estudio y atribución de nuevas piezas al orfebre compostelano Jacobo Pecul Montenegro (1753-1817, cuya producción refleja una estética influida por una parte de las formas francesas aprendidas de su padre, Claudio Pecul, y por otra de los artistas gallegos, cómo Ferreiro o Simón Rodríguez. Se han seleccionado veinticuatro nuevas piezas entre cruces parroquiales, cálices, copones, incensarios, navetas y ostensorios, las cuales aparecen referenciadas en el Libro de Caja de Pecul, extractado por Couselo Bouzas en su Galicia Artística, y catalogadas en el Archivo Diocesano de la Iglesia Católica. Dichas obras han sido estudiadas y atribuidas a Jacobo Pecul siguiendo las directrices

  19. Prevalence of acute and chronic viral seropositivity and characteristics of disease in patients with psoriatic arthritis treated with cyclosporine: a post hoc analysis from a sex point of view on the observational study of infectious events in psoriasis complicated by active psoriatic arthritis

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    Colombo D

    2015-12-01

    Full Text Available Delia Colombo,1 Sergio Chimenti,2 Paolo Antonio Grossi,3 Antonio Marchesoni,4 Federico Bardazzi,5 Fabio Ayala,6 Lucia Simoni,7 Donatella Vassellatti,1 Gilberto Bellia1 On behalf of SYNERGY Study Group 1Novartis Farma Italia, Origgio (VA, 2Tor Vergata Polyclinic Rome, 3Macchi Hospital and Foundation, Varese, 4Orthopaedic Institute Pini, Milan, 5S Orsola-Malpighi Polyclinic, Bologna, 6University Federico II Naples, 7MediData srl, Modena, Italy Background: Sex medicine studies have shown that there are sex differences with regard to disease characteristics in immune-mediated inflammatory diseases, including psoriasis, in immune response and susceptibility to viral infections. We performed a post hoc analysis of the Observational Study of infectious events in psoriasis complicated by active psoriatic arthritis (SYNERGY study in patients with psoriatic arthritis (PsA treated with immunosuppressive regimens including cyclosporine, in order to evaluate potential between-sex differences in severity of disease and prevalence of viral infections.Methods: SYNERGY was an observational study conducted in 24 Italian dermatology clinics, which included 238 consecutively enrolled patients with PsA, under treatment with immunosuppressant regimens including cyclosporin A. In this post hoc analysis, patients' demographical data and clinical characteristics of psoriasis, severity and activity of PsA, prevalence of seropositivity for at least one viral infection, and treatments administered for PsA and infections were compared between sexes.Results: A total of 225 patients were evaluated in this post hoc analysis, and 121 (54% were males. Demographic characteristics and concomitant diseases were comparable between sexes. Statistically significant sex differences were observed at baseline in Psoriasis Area and Severity Index score (higher in males, mean number of painful joints, Bath Ankylosing Spondylitis Disease Activity Index, and the global activity of disease

  20. Gender difference in response predictors after 1-year exenatide therapy twice daily in type 2 diabetic patients: a real world experience

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    Anichini R

    2013-04-01

    Full Text Available Roberto Anichini,1 Sabrina Cosimi,2 Alberto Di Carlo,3 Paola Orsini,4 Alessandra De Bellis,1 Giuseppe Seghieri,1 Flavia Franconi,5 Fabio Baccetti6 1Diabetes Unit, Spedali Riuniti, Pistoia, Italy; 2Diabetes Unit, Hospital of Versilia, Camaiore (LU, Italy; 3Diabetes Unit, Hospital of Lucca, Italy; 4Diabetes Unit, Hospital of Livorno, Italy; 5Department of Biochemical Sciences, University of Sassari, Italy; 6Diabetes Unit, Hospital of Massa, Italy Purpose: To investigate whether gender affects therapeutic response by exenatide twice a day (BID in type 2 diabetes by using a database concerning patients monitored by five outpatient clinics in Tuscany, Italy. Patients and methods: We considered a cohort of 315 (154 male/161 female patients experiencing therapeutic failure while on oral therapy (metformin, or combination therapy metformin + sulphonylureas, who were given exenatide (10 µg/BID and who fully completed 4 months, 8 months, and 12 months of follow-ups. Results: Among patients stratified by gender and well matched for age, body mass index, and hemoglobin A1c (HbA1c, it was found that the length of disease was longer in females than in males (12 ± 8 years versus 10 ± 7 years; P = 0.037, and the ratio of patients on metformin to those on combination therapy was higher in men (P = 0.018. Target glycemic response (1-year HbA1c ≤ 7% was achieved in a significantly higher proportion of males than females (38% versus 27%;Χ2 = 4.66; P = 0.03. Target weight loss expressed as 1-year weight percent fall from baseline ≥ 75th percentile (8.5% was significantly higher in females at 8 and 12 months (P < 0.05; for both. One-year glycemic target response was inversely related to baseline HbA1c levels and diabetes duration among males, while metformin therapy (compared to oral combination therapy was a significant predictor of better glycemic targets among females. Homeostasis model assessment-B, measured in 117 patients, predicted hypoglycemic

  1. Correlating Petrophysical Well Logs Using Fractal-based Analysis to Identify Changes in the Signal Complexity Across Neutron, Density, Dipole Sonic, and Gamma Ray Tool Types

    Science.gov (United States)

    Matthews, L.; Gurrola, H.

    2015-12-01

    Typical petrophysical well log correlation is accomplished by manual pattern recognition leading to subjective correlations. The change in character in a well log is dependent upon the change in the response of the tool to lithology. The petrophysical interpreter looks for a change in one log type that would correspond to the way a different tool responds to the same lithology. To develop an objective way to pick changes in well log characteristics, we adapt a method of first arrival picking used in seismic data to analyze changes in the character of well logs. We chose to use the fractal method developed by Boschetti et al[1] (1996). This method worked better than we expected and we found similar changes in the fractal dimension across very different tool types (sonic vs density vs gamma ray). We reason the fractal response of the log is not dependent on the physics of the tool response but rather the change in the complexity of the log data. When a formation changes physical character in time or space the recorded magnitude in tool data changes complexity at the same time even if the original tool response is very different. The relative complexity of the data regardless of the tool used is dependent upon the complexity of the medium relative to tool measurement. The relative complexity of the recorded magnitude data changes as a tool transitions from one character type to another. The character we are measuring is the roughness or complexity of the petrophysical curve. Our method provides a way to directly compare different log types based on a quantitative change in signal complexity. For example, using changes in data complexity allow us to correlate gamma ray suites with sonic logs within a well and then across to an adjacent well with similar signatures. Our method creates reliable and automatic correlations to be made in data sets beyond the reasonable cognitive limits of geoscientists in both speed and consistent pattern recognition. [1] Fabio Boschetti

  2. The impact of age and severity of comorbid illness on outcomes after isolated aortic valve replacement for aortic stenosis

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    Russo MJ

    2015-05-01

    Full Text Available Mark J Russo,1,2 Alexander Iribarne,3 Emily Chen,2 Ashwin Karanam,2 Chris Pettit,2 Fabio Barili,4 Atman P Shah,5 Craig R Saunders1,2 1Barnabas Health Hospital, Newark/Livingston, NJ, USA; 2Barnabas Health Cardiovascular Clinical Research Center, Newark, NJ, USA; 3Duke University, Durham, NC, USA; 4Department of Cardiovascular Surgery, S Croce Hospital, Cuneo, Italy; 5University of Chicago, Chicago, IL, USA Objectives: This study examines outcomes in a national sample of patients undergoing isolated aortic valve replacement (AVR for aortic stenosis, with particular focus on advanced-age patients and those with extreme severity of comorbid illness (SOI. Methods: Data were obtained from the Nationwide Inpatient Sample and included all patients undergoing AVRs performed from January 1, 2006 to December 31, 2008. Patients with major concomitant cardiac procedures, as well as those aged <20 years, and those with infective endocarditis or aortic insufficiency without aortic stenosis, were excluded from analysis. The analysis included 13,497 patients. Patients were stratified by age and further stratified by All Patient Refined Diagnosis Related Group SOI into mild/moderate, major, and extreme subgroups. Results: Overall in-hospital mortality was 2.96% (n=399; in-hospital mortality for the ≥80-year-old group (n=139, 4.78% was significantly higher than the 20- to 49-year-old (n=9, 0.84%, P<0.001 or 50- to 79-year-old (n=251, 2.64%, P<0.001 groups. In-hospital mortality was significantly higher in the extreme SOI group (n=296, 15.33% than in the minor/moderate (n=22, 0.35%, P<0.001 and major SOI groups (n=81, 1.51%, P<0.001. Median in-hospital costs in the mild/moderate, major, and extreme SOI strata were $29,202.08, $36,035.13, and $57,572.92, respectively. Conclusion: In the minor, moderate, and major SOI groups, in-hospital mortality and costs are low regardless of age; these groups represent >85% of patients undergoing isolated AVR for aortic

  3. The impact of internalizing symptoms on autistic traits in adolescents with restrictive anorexia nervosa

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    Calderoni S

    2015-01-01

    Full Text Available Sara Calderoni,1,* Pamela Fantozzi,1,* Giulia Balboni,2 Veronica Pagni,1 Emilio Franzoni,3 Fabio Apicella,1 Antonio Narzisi,1 Sandra Maestro,1 Filippo Muratori1,4 1IRCCS Stella Maris Foundation, 2Department of Surgery, Medical, Molecular and Critical Area Pathology, University of Pisa, Pisa, Italy; 3Child Neuropsychiatric Unit, Women, Children and Adolescents Health Department, University Hospital S Orsola-Malpighi, Bologna, Italy; 4Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy *These authors contributed equally to this work Background: Although previous studies indicated a positive association between restrictive anorexia-nervosa (AN-R and autistic traits, the potential interference of psychiatric internalizing comorbidity on this association is not yet fully investigated.Materials and methods: The aim of this study was to explore autistic traits and internalizing psychopathology in adolescents (age range: 11.7–17.2 years with AN-R. Twenty-five patients referred to two tertiary-care hospitals were compared to a large control group (N=170 with no differences in age and sex. AN-R patients and controls filled out instruments assessing autistic traits (autism spectrum quotient [AQ], psychopathology (youth self-report [YSR] 11–18, and eating patterns (eating attitude test [EAT]. In order to disentangle the possible mediating role of internalizing symptoms on autistic traits, two separate control groups (called True and False healthy control, both composed of 25 eating-problem-free participants were derived from the whole control group on the basis of the presence or absence of internalizing problems in the YSR.Results: AN-R patients scored significantly higher on AQ compared to the whole control group and to controls without internalizing problems (True HC, but these differences disappeared when only controls with internalizing problems (False HC were considered.Conclusion: Autistic traits in AN

  4. 5-grass pollen tablets achieve disease control in patients with seasonal allergic rhinitis unresponsive to drugs: a real-life study

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    Pastorello EA

    2013-12-01

    Full Text Available Elide Anna Pastorello,1 Laura Losappio,1 Stefania Milani,2 Giuseppina Manzotti,3 Valentina Fanelli,4 Valerio Pravettoni,5 Fabio Agostinis,6 Alberto Flores D’Arcais,7 Ilaria Dell'Albani,8 Paola Puccinelli,9 Cristoforo Incorvaia,10 Franco Frati81Allergy and Immunology Department, Niguarda Hospital, Milan, 2Allergy Department, San Marco General Hospital, Bergamo, 3Allergy Department, Treviglio Hospital, Bergamo, 4Allergy Department, Italian Institute for Auxology, Milan, 5Clinical Allergy and Immunology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, 6Department of Pediatrics, Riuniti Hospital, Bergamo, 7Department of Pediatrics, Legnano Hospital, Milan, 8Medical and Scientific Department, Stallergenes Italy, Milan, 9Regulatory Department, Stallergenes Italy, Milan, 10Allergy/Pulmonary Rehabilitation, ICP Hospital, Milan, ItalyBackground: An important subpopulation in allergic rhinitis is represented by patients with severe form of disease that is not responsive to drug treatment. It has been reported that grass pollen subcutaneous immunotherapy is effective in drug-resistant patients. In a real-life study, we evaluated the efficacy of 5-grass pollen tablets in patients with grass pollen-induced allergic rhinitis not responsive to drug therapy.Methods: We carried out this multicenter observational study in adults and adolescents with grass-induced allergic rhinitis not responsive to drug therapy who were treated for a year with 5-grass pollen tablets. Clinical data collected before and after sublingual immunotherapy (SLIT included Allergic Rhinitis and its Impact on Asthma (ARIA classification of allergic rhinitis, response to therapy, and patient satisfaction.Results: Forty-seven patients entered the study. By ARIA classification, three patients had moderate to severe intermittent allergic rhinitis, ten had mild persistent allergic rhinitis, and 34 had moderate to severe persistent allergic rhinitis. There were no cases

  5. Lung and kidney: a dangerous liaison? A population-based cohort study in COPD patients in Italy

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    Fedeli U

    2017-01-01

    Full Text Available Ugo Fedeli,1 Alfredo De Giorgi,2 Nicola Gennaro,1 Eliana Ferroni,1 Massimo Gallerani,3 Dimitri P Mikhailidis,4 Roberto Manfredini,2 Fabio Fabbian2 1Epidemiological Department, Veneto Region, 2Department of Medical Sciences, Clinica Medica Unit, School of Medicine, University of Ferrara, 3Department of Internal Medicine, University Hospital of Ferrara, Ferrara, Italy; 4Department of Clinical Biochemistry (Vascular Disease Prevention Clinic, University College London Medical School, London, UK Background: COPD is among the major causes of death, and it is associated with several comorbid conditions. Chronic kidney disease (CKD is frequently diagnosed in older people living in Western societies and could impact COPD patients’ mortality. We evaluated the relationship between burden of comorbidities, CKD, and mortality in a population-based cohort of patients discharged with a diagnosis of COPD.Methods: A longitudinal cohort study was conducted evaluating 27,272 COPD patients. Recruitment of COPD subjects and identification of CKD and other comorbidities summarized by the Charlson comorbidity index (CCI were based on claims data coded according to the International Classification of Diseases, 9th Revision, Clinical Modification (ICD-9-CM. Severity of COPD was classified by hospital diagnosis or exemption from medical charges due to respiratory failure or previous hospitalizations for COPD. The impact of comorbidities on survival was assessed by Cox regression.Results: Less than 40% of patients were still alive at the end of a median follow-up of 37 months (17 months for patients who died and 56 months for those alive at the end of follow-up. After adjustment for age, gender, and severity score of COPD, CKD (hazard ratio =1.36, 95% confidence interval 1.30–1.42 independently from comorbidities summarized by the CCI was a significant risk factor for mortality.Conclusion: In spite of limitations due to the use of claims data, long-term survival

  6. Negatively charged silver nanoparticles with potent antibacterial activity and reduced toxicity for pharmaceutical preparations

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    Salvioni L

    2017-03-01

    Full Text Available Lucia Salvioni,1 Elisabetta Galbiati,1 Veronica Collico,1 Giulia Alessio,1 Svetlana Avvakumova,1 Fabio Corsi,2,3 Paolo Tortora,1 Davide Prosperi,1 Miriam Colombo1 1Nanobiolab, Department of Biotechnology and Bioscience, University of Milano-Bicocca, 2Biological and Clinical Science Department, University of Milan, Milano, 3Surgery Department, Breast Unit, IRCCS S Maugeri Foundation, Pavia, Italy Background: The discovery of new solutions with antibacterial activity as efficient and safe alternatives to common preservatives (such as parabens and to combat emerging infections and drug-resistant bacterial pathogens is highly expected in cosmetics and pharmaceutics. Colloidal silver nanoparticles (NPs are attracting interest as novel effective antimicrobial agents for the prevention of several infectious diseases.Methods: Water-soluble, negatively charged silver nanoparticles (AgNPs were synthesized by reduction with citric and tannic acid and characterized by transmission electron microscopy, dynamic light scattering, zeta potential, differential centrifuge sedimentation, and ultraviolet–visible spectroscopy. AgNPs were tested with model Gram-negative and Gram-positive bacteria in comparison to two different kinds of commercially available AgNPs.Results: In this work, AgNPs with higher antibacterial activity compared to the commercially available colloidal silver solutions were prepared and investigated. Bacteria were plated and the antibacterial activity was tested at the same concentration of silver ions in all samples. The AgNPs did not show any significant reduction in the antibacterial activity for an acceptable time period. In addition, AgNPs were transferred to organic phase and retained their antibacterial efficacy in both aqueous and nonaqueous media and exhibited no toxicity in eukaryotic cells.Conclusion: We developed AgNPs with a 20 nm diameter and negative zeta potential with powerful antibacterial activity and low toxicity compared

  7. Presentación y contenido

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    Pappenheim Murcia Ruth

    1995-06-01

    Full Text Available

    Este número recoge aportes de profesores de los Departamentos de Lingüística y Literatura de la Universidad Nacional en campos de actual relevancia para el estudio del lenguaje. Se inicia la sección de artículos con un sólido planteamiento teórico de la semántica aplicada al análisis de los prefijos del español. Este escrito se circunscribe en el desarrollo de una larga trayectoria de su autor, Bernardo Morales, y está relacionado con sus artículos "Hacia una visión generativista de la semántica lexical" en el número 6 y "Sobre la estructura semántica de las palabras  autosemánticas" en el número 7 de esta revista. Seguidamente hemos incluido cuatro artículos que muestran un amplio espectro alrededor del tema del "texto", desde diferentes perspectivas y en función de diversos campos de acción; los artículos de Sergio Bolaños, Neyla Pardo y Fabio Jurado giran alrededor de temas pedagógicos. El primero propone un modelo de análisis textual de interés para quienes se dedican a la lingüística del texto y elaboran material didáctico, o forman profesionales en este campo. El segundo es un análisis crítico de las implicaciones de principios de la  etnolingüística y del análisis del discurso en prácticas pedagógicas en cursos de español. El tercero problematiza la enseñanza tradicional de la lectura, por haber impuesto un procedimiento que no le da cabida a la incertidumbre en el proceso de comunicación escrita.

  8. Posterior composite restoration update: focus on factors influencing form and function

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    Bohaty BS

    2013-05-01

    Full Text Available Brenda S Bohaty,1,2 Qiang Ye,3 Anil Misra,3,4 Fabio Sene,6 Paulette Spencer3,51Department of Pediatric Dentistry, University of Missouri-Kansas City School of Dentistry, Kansas City, MO, USA; 2Department of Pediatric Dentistry, Children's Mercy Hospital, Kansas City, MO, USA; 3Bioengineering Research Center, 4Department of Civil, Environmental, and Architectural Engineering, 5Department of Mechanical Engineering, University of Kansas, Lawrence, KS, USA; 6Department of Restorative Dentistry, State University of Londrina, School of Dentistry, Londrina, BrazilAbstract: Restoring posterior teeth with resin-based composite materials continues to gain popularity among clinicians, and the demand for such aesthetic restorations is increasing. Indeed, the most common aesthetic alternative to dental amalgam is resin composite. Moderate to large posterior composite restorations, however, have higher failure rates, more recurrent caries, and increased frequency of replacement. Investigators across the globe are researching new materials and techniques that will improve the clinical performance, handling characteristics, and mechanical and physical properties of composite resin restorative materials. Despite such attention, large to moderate posterior composite restorations continue to have a clinical lifetime that is approximately one-half that of the dental amalgam. While there are numerous recommendations regarding preparation design, restoration placement, and polymerization technique, current research indicates that restoration longevity depends on several variables that may be difficult for the dentist to control. These variables include the patient's caries risk, tooth position, patient habits, number of restored surfaces, the quality of the tooth–restoration bond, and the ability of the restorative material to produce a sealed tooth–restoration interface. Although clinicians tend to focus on tooth form when evaluating the success and failure of

  9. Health Services OutPatient Experience questionnaire: factorial validity and reliability of a patient-centered outcome measure for outpatient settings in Italy

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    Coluccia A

    2014-09-01

    Full Text Available Anna Coluccia, Fabio Ferretti, Andrea PozzaDepartment of Medical Sciences, Surgery and Neurosciences, Santa Maria alle Scotte University Hospital, University of Siena, Siena, ItalyPurpose: The patient-centered approach to health care does not seem to be sufficiently developed in the Italian context, and is still characterized by the biomedical model. In addition, there is a lack of validated outcome measures to assess outpatient experience as an aspect common to a variety of settings. The current study aimed to evaluate the factorial validity, reliability, and invariance across sex of the Health Services OutPatient Experience (HSOPE questionnaire, a short ten-item measure of patient-centeredness for Italian adult outpatients. The rationale for unidimensionality of the measure was that it could cover global patient experience as a process common to patients with a variety of diseases and irrespective of the phase of treatment course.Patients and methods: The HSOPE was compiled by 1,532 adult outpatients (51% females, mean age 59.22 years, standard deviation 16.26 receiving care in ten facilities at the Santa Maria alle Scotte University Hospital of Siena, Italy. The sample represented all the age cohorts. Twelve percent were young adults, 57% were adults, and 32% were older adults. Exploratory and confirmatory factor analyses were conducted to evaluate factor structure. Reliability was evaluated as internal consistency using Cronbach’s α. Factor invariance was assessed through multigroup analyses.Results: Both exploratory and confirmatory analyses suggested a clearly defined unidimensional structure of the measure, with all the ten items having salient loadings on a single factor. Internal consistency was excellent (α=0.95. Indices of model fit supported a single-factor structure for both male and female outpatient groups. Young adult outpatients had significantly lower scores on perceived patient-centeredness relative to older adults. No

  10. Clinical utility of eslicarbazepine: current evidence

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    Zaccara G

    2015-02-01

    Full Text Available Gaetano Zaccara,1 Fabio Giovannelli,1,2 Massimo Cincotta,1 Alessia Carelli,3 Alberto Verrotti31Department of Medicine, Unit of Neurology, Florence Health Authority, Florence, Italy; 2Department of Neuroscience, Psychology, Pharmacology and Child Health (NEUROFARBA, University of Florence, Florence, Italy; 3Department of Pediatrics, University of Perugia, Perugia, ItalyAbstract: Eslicarbazepine acetate (ESL is a new antiepileptic drug whose mechanism of action is blockade of the voltage-gated sodium channel (VGSC. However, in respect to carbamazepine and oxcarbazepine, the active ESL metabolite (eslicarbazepine affects slow inactivation of VGSC and has a similar affinity for the inactivated state and a lower affinity for the resting state of the channel. This new antiepileptic drug has been recently approved in Europe (trade name Zebinix and in the United States (trade name Stedesa for adjunctive treatment in adult subjects with partial-onset seizures, with or without secondary generalization. Following oral administration, ESL is rapidly and extensively metabolized by hepatic esterases to eslicarbazepine. This active metabolite has a linear pharmacokinetic profile, a low binding to plasma proteins (<40%, and a half-life of 20–24 hours and is mainly excreted by kidneys in an unchanged form or as glucuronide conjugates. ESL is administered once a day and has a low potential for drug–drug interactions. Efficacy and safety of this drug in patients with focal seizures have been assessed in four randomized clinical trials, and responder rates (percentage of patients with a ≥50% improvement of their seizures ranged between 17% and 43%. Adverse events were usually mild to moderate, and the most common were dizziness, somnolence, diplopia, abnormal coordination, blurred vision, vertigo, headache, fatigue, nausea, and vomiting. ESL may be considered an interesting alternative to current antiepileptic drugs for the treatment of drug-resistant focal

  11. Preliminary results from Submarine Ring of Fire 2012 - NE Lau: First explorations of hydrothermally active volcanoes across the supra-subduction zone and a return to the West Mata eruption site

    Science.gov (United States)

    Resing, J.; Embley, R. W.

    2012-12-01

    , Fabio Caratori-Tontini, Rick Davis, Kevin Roe, Edward Mitchell, Paula Keener-Chavis Carolyn Sheehan, Peter Crowhurst, Simon Richards,and Volker Ratmeyer along with the Quest-4000 team. .

  12. Sugammadex for reversal of neuromuscular blockade: a retrospective analysis of clinical outcomes and cost-effectiveness in a single center

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    Carron M

    2016-02-01

    Full Text Available Michele Carron, Fabio Baratto, Francesco Zarantonello, Carlo Ori Department of Medicine, Anesthesiology and Intensive Care, University of Padova, Padova, Italy Objective: The aim of the study is to evaluate the clinical and economic impact of introducing a rocuronium–neostigmine–sugammadex strategy into a cisatracurium–neostigmine regimen for neuromuscular block (NMB management. Methods: We conducted a retrospective analysis of clinical outcomes and cost-effectiveness in five operating rooms at University Hospital of Padova. A clinical outcome evaluation after sugammadex administration as first-choice reversal drug in selected patients (rocuronium–sugammadex and as rescue therapy after neostigmine reversal (rocuronium–neostigmine–sugammadex compared to control was performed. A cost-analysis of NMB management accompanying the introduction of a rocuronium–neostigmine–sugammadex strategy into a cisatracurium–neostigmine regimen was carried out. To such purpose, two periods were compared: 2011–2012, without sugammadex available; 2013–2014, with sugammadex available. A subsequent analysis was performed to evaluate if sugammadex replacing neostigmine as first choice reversal drug is cost-effective. Results: The introduction of a rocuronium–neostigmine–sugammadex strategy into a cisatracurium–neostigmine regimen reduced the average cost of NMB management by 36%, from €20.8/case to €13.3/case. Patients receiving sugammadex as a first-choice reversal drug (3% exhibited significantly better train-of-four ratios at extubation (P<0.001 and were discharged to the surgical ward (P<0.001 more rapidly than controls. The cost-saving of sugammadex as first-choice reversal drug has been estimated to be €2.9/case. Patients receiving sugammadex as rescue therapy after neostigmine reversal (3.2% showed no difference in time to discharge to the surgical ward (P=0.44 compared to controls. No unplanned intensive care unit (ICU

  13. Effect of prophylactic timolol 0.1% gel on intraocular pressure after an intravitreal injection of ranibizumab: a randomized study

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    Pece A

    2016-06-01

    Full Text Available Alfredo Pece,1 Davide Allegrini,1 Giovanni Montesano,2 Andrea Fabio Dimastrogiovanni1 1Eye Clinic, Melegnano Hospital, Vizzolo Predabissi, 2Eye Clinic, San Paolo Hospital, Università di Milano, Milano, Italy Purpose: The purpose of this study is to make a prospective evaluation of the effect of timolol 0.1% eye gel on short-term intraocular pressure (IOP after an intravitreal injection (IVI of ranibizumab. Participants and methods: One hundred and fifty eyes of 150 IVI-naïve patients with macular edema caused by various pathological conditions (age-related macular degeneration, central or branch retinal vein occlusion, and diabetic retinopathy were scheduled to undergo an IVI of ranibizumab (0.5 mg/0.05 cc. The patients were randomly divided into three groups: 50 were not treated with timolol before the IVI (group 1; 50 received an instillation of timolol 0.1% eye gel the evening before the IVI (group 2; and 50 received an instillation of timolol 0.1% eye gel 2 hours before the IVI (group 3. The incidence of clinically significant intraocular hypertensive spikes (>25 mmHg and >40 mmHg was then assessed. Results: Our findings showed that mean IOP at baseline was significantly higher than at both 5 and 60 minutes after IVI (P<0.01. Spikes of >25 mmHg were recorded at either time in 27 patients (54% in group 1, 23 patients (44% in group 2, and 24 patients (48% in group 3. None of the between-group differences were significant. Spikes of >40 mmHg (which were only detected 5 minutes after IVI were recorded in nine (18%, eight (16%, and one patient (2% in groups 1, 2, and 3, respectively. The only significant difference was between the control and group 3 (P=0.012. Conclusion: An increase in IOP after antivascular endothelial growth factor IVI is a frequent complication. The prophylactic use of timolol 0.1% gel effectively reduced the mean IOP when administered 2 hours before IVI and was also effective in preventing dangerous IOP spikes of >40 mm

  14. Active home-based cancer treatment

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    Bordonaro S

    2012-06-01

    Full Text Available Sebastiano Bordonaro Fabio Raiti, Annamaria Di Mari, Calogera Lopiano, Fabrizio Romano, Vitalinda Pumo, Sebastiano Rametta Giuliano, Margherita Iacono, Eleonora Lanteri, Elena Puzzo, Sebastiano Spada, Paolo TralongoUOC Medical Oncology, RAO, ASP 8 Siracusa, ItalyBackground: Active home-based treatment represents a new model of health care. Chronic treatment requires continuous access to facilities that provide cancer care, with considerable effort, particularly economic, on the part of patients and caregivers. Oral chemotherapy could be limited as a consequence of poor compliance and adherence, especially by elderly patients.Methods: We selected 30 cancer patients referred to our department and treated with oral therapy (capecitabine, vinorelbine, imatinib, sunitinib, sorafenib, temozolomide, ibandronate. This pilot study of oral therapy in the patient’s home was undertaken by a doctor and two nurses with experience in clinical oncology. The instruments used were clinical diaries recording home visits, hospital visits, need for caregiver support, and a questionnaire specially developed by the European Organization for Research and Treatment of Cancer (EORTC, known as the QLQ-C30 version 2.0, concerning the acceptability of oral treatment from the patient’s perspective.Results: This program decreased the need to access cancer facilities by 98.1%, promoted better quality of life for patients, as reflected in increased EORTC QLQ-C30 scores over time, allowing for greater adherence to oral treatment as a result of control of drug administration outside the hospital. This model has allowed treatment of patients with difficult access to care (elderly, disabled or otherwise needed caregivers that in the project represent the majority (78% of these.Conclusions: This model of active home care improves quality of life and adherence with oral therapy, reduces the need to visit the hospital, and consequently decreases the number of lost hours of work on

  15. PREFACE: DISCRETE 2010: Symposium on Prospects in the Physics of Discrete Symmetries

    Science.gov (United States)

    Di Domenico, Antonio; Bini, Cesare; Bloise, Caterina; Bossi, Fabio; Faccini, Riccardo; Gauzzi, Paolo; Isidori, Gino; Lipari, Paolo; Ludovici, Lucio; Silvestrini, Luca

    2011-12-01

    , Portugal, from 3 to 7 December 2012. Roma, November 2011 The Editors Antonio Di Domenico Cesare Bini Caterina Bloise Fabio Bossi Riccardo Faccini Paolo Gauzzi Gino Isidori Paolo Lipari Lucio Ludovici Luca Silvestrini The PDF file also contains committee, secretariat, sponsor and participant lists, plus the conference poster and photograph.

  16. Advances in diagnosis and treatment of trigeminal neuralgia

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    Montano N

    2015-02-01

    Full Text Available Nicola Montano,1 Giulio Conforti,1 Rina Di Bonaventura,1 Mario Meglio,2 Eduardo Fernandez,1 Fabio Papacci1 1Institute of Neurosurgery, Catholic University, Rome, 2Institute of Neurosurgery, Azienda Ospedaliera Universitaria Integrata, Verona, Italy Abstract: Various drugs and surgical procedures have been utilized for the treatment of trigeminal neuralgia (TN. Despite numerous available approaches, the results are not completely satisfying. The need for more contemporaneous drugs to control the pain attacks is a common experience. Moreover, a number of patients become drug resistant, needing a surgical procedure to treat the neuralgia. Nonetheless, pain recurrence after one or more surgical operations is also frequently seen. These facts reflect the lack of the precise understanding of the TN pathogenesis. Classically, it has been related to a neurovascular compression at the trigeminal nerve root entry-zone in the prepontine cistern. However, it has been evidenced that in the pain onset and recurrence, various neurophysiological mechanisms other than the neurovascular conflict are involved. Recently, the introduction of new magnetic resonance techniques, such as voxel-based morphometry, diffusion tensor imaging, three-dimensional time-of-flight magnetic resonance angiography, and fluid attenuated inversion recovery sequences, has provided new insight about the TN pathogenesis. Some of these new sequences have also been used to better preoperatively evidence the neurovascular conflict in the surgical planning of microvascular decompression. Moreover, the endoscopy (during microvascular decompression and the intraoperative computed tomography with integrated neuronavigation (during percutaneous procedures have been recently introduced in the challenging cases. In the last few years, efforts have been made in order to better define the optimal target when performing the gamma knife radiosurgery. Moreover, some authors have also evidenced that

  17. Global Time Variability in the Thermal Plasma Composition of the Saturnian Magnetosphere

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    Ip, W.

    2013-12-01

    The Saturnian magnetosphere is characterized by strong coupling between the charged particles and the neutral gas cloud emitted from Enceladus and the rings. Besides the mass-loading effect due to ionization of the water-group gas, the charge transfer process leading to the generation of energetic neutral atoms is a key process of particle loss and atmospheric precipitation. Detailed measurements by the plasma instruments like CAPS and MIMI have provided many insights to the magnetospheric composition and dynamics driven by such plasma-gas interaction. For example, a statistical study of the CAPS measurements by Thomsen et al. (2010) has shown the relative abundances and radial profiles of different ion species in the corotating thermal plasma disc. Another interesting result has to do with the seasonal variability of the suprathermal O2+ molecular ions detected by the CHEMS/MIMI experiment (Christon et al., 2013) which might have to do with the extended oxygen atmosphere of the ring system (Tseng et al., 2010). In this work, we will use a time-dependent radial diffusion transport model coupled with ion chemistry calculation (Ip, 2000) to simulate the global distributions of various ions (H+, H2+, O+, OH+, H2O+, H3O+, and O2+ )between the outer edge of the A ring to the orbit of Titan. Our parametric study will examine how the thermal ion composition of the Saturnian magnetosphere would be affected by solar cycle effect, seasonal variation of the ring atmosphere, and the suprathermal electron flux. Christon, S.P., Hamilton, D.C., DiFabio, R.D., Mitchell, D.G., Krimigis, S.M., and Jontof-Hutter, D.S., J. Geophys. Res., 118, 3446-3462, 2013. Ip, W.-H., Planet. Space Sci., 48, 775-783, 2000. Thomsen, M.F., Reisenfeld, D.B., Delapp, D.M., Tokar, R.C., Young, D.T., Crary, F.J., Sittler, E.C., McGraw, M.A., and Williams, J.D., J. Geophys. Res., 115, A10220, 2010. Tseng, W.-L., Ip, W.-H., Johnson, R.E., Cassidy, T.A., and Elrod, M.K., Icarus, 206, 382-389, 2010.

  18. Central serous chorioretinopathy: a pathogenetic model

    Directory of Open Access Journals (Sweden)

    et al

    2011-02-01

    Full Text Available Antonio Caccavale1, Filippo Romanazzi1, Manuela Imparato1, Angelo Negri2, Anna Morano3, Fabio Ferentini21Department of Ophthalmology, Neuropthalmology and Ocular Immunology Service, 2Department of Ophthalmology, Hospital “C. Cantù”, Abbiategrasso, Milan, Italy; 3University Eye Clinic, Foundation IRCCS San Matteo Hospital, Pavia, ItalyAbstract: Despite numerous studies describing predominantly its demography and clinical course, many aspects of central serous chorioretinopathy (CSCR remain unclear. Perhaps the major impediment to finding an effective therapy is the difficulty of performing studies with large enough cohorts, which has meant that clinicians have focused more on therapy than on a deeper understanding of the pathogenesis of the disease. Hypotheses on the pathogenesis of CSCR have ranged from a basic alteration in the choroid to an involvement of the retinal pigment epithelium (RPE. Starting from evidence that affected subjects often present a personality prone to stress with altered pituitary–hypothalamic axis response (HPA and that they have higher levels of serum and urinary cortisol and catecholamines than healthy subjects, we hypothesize a cascade of events that may lead to CSCR through hypercoagulability and augmented platelet aggregation. In particular we investigated the role of tissue plasminogen activator, increasing plasminogen activator inhibitor 1 (PAI-1, and plasmin-α2- plasmin inhibitor complexes. We reviewed the different therapeutic approaches, including adrenergic antagonists, carbonic anhydrase inhibitors, mifepristone, ketoconazole, laser photocoagulation, intravitreal injection of bevacizumab, and photodynamic therapy with verteporfin (PDT and our model of pathogenesis seems to be in agreement with the clinical effects obtained from these treatments. In accord with our thesis, we began to treat a group of patients affected by CSCR with low-dose aspirin (75–100 mg, because of its effectiveness in other

  19. Knowledge among physical education professionals about poliomyelitis and post-poliomyelitis syndrome: a cross-sectional study in Brazil

    Directory of Open Access Journals (Sweden)

    Sousa BS

    2013-08-01

    Full Text Available Claudio Andre Barbosa de Lira,1 Taíza Márcia de Almeida Alves,1 Luiz Fernando Peixinho-Pena,2 Bolivar Saldanha Sousa,3,4 Marcos Gonçalves de Santana,1 Sandra Aparecida Benite-Ribeiro,1 Marilia dos Santos Andrade,2 Rodrigo Luiz Vancini21Setor de Fisiologia Humana e do Exercício, Universidade Federal de Goiás, Câmpus Jataí, Jataí, 2Departamento de Fisiologia, Universidade Federal de São Paulo, São Paulo, Brazil; 3Faculdade de Ciências Médicas da Santa Casa de São Paulo, São Paulo, Brazil; 4Instituto Israelita de Ensino e Pesquisa Albert Einstein, São Paulo, BrazilBackground: Post-poliomyelitis syndrome is a clinical condition that can affect poliomyelitis survivors with the onset of new symptoms several years after the acute disease. These symptoms include new muscular weakness, fatigue, pain, onset or aggravation of muscle atrophy, muscle cramps, onset or aggravation of pre-existing difficulties in accomplishing daily life activities, cold intolerance, sleep disorders, dysphonia or dysphagia, and respiratory deficiency. The treatment of post-poliomyelitis syndrome requires a multiprofessional health team because the rehabilitation procedures include lifestyle changes, physiotherapy, avoidance of secondary complications, and physical exercise. As physical exercise is prescribed by physical education professionals, the assessment of knowledge about post-poliomyelitis syndrome among these professionals is very relevant. The aim of this study was to evaluate poliomyelitis and post-poliomyelitis syndrome knowledge among physical education professionals in Brazil.Methods: We invited participants with an academic degree in physical education (n = 217 to participate in this study. A self-administered survey (30 questions was designed to probe knowledge about poliomyelitis and post-poliomyelitis syndrome. From the survey, we created a questionnaire to evaluate the performance of the professionals. The questionnaire was composed of 20

  20. Development of a core outcome set for medication review in older patients with multimorbidity and polypharmacy: a study protocol

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    Beuscart JB

    2017-08-01

    Full Text Available Jean-Baptiste Beuscart,1 Olivia Dalleur,1 Benoit Boland,2 Stefanie Thevelin,1 Wilma Knol,3 Shane Cullinan,4 Claudio Schneider,5 Denis O’Mahony,6 Nicolas Rodondi,4,7 Anne Spinewine1,8 1Université catholique de Louvain, Louvain Drug Research Institute, Clinical Pharmacy Research Group, Brussels, Belgium; 2Geriatric Medicine, Cliniques universitaires Saint-Luc, Brussels, Université catholique de Louvain, Belgium; 3Department of Geriatric Medicine and Expertise Centre Pharmacotherapy in Old Persons (EPHOR, University Medical Centre Utrecht, Netherlands; 4School of Pharmacy, Royal College of Surgeons in Ireland, Dublin, Ireland; 5Department of General Internal Medicine, Bern University Hospital, Bern, Switzerland; 6Department of Medicine (Geriatrics, University College Cork, Cork, Ireland; 7Institute of Primary Health Care (BIHAM, University of Bern, Bern, Switzerland; 8Université catholique de Louvain, CHU UCL Namur, Pharmacy Department, Yvoir, Belgium Background: Medication review has been advocated to address the challenge of polypharmacy in older patients, yet there is no consensus on how best to evaluate its efficacy. Heterogeneity of outcomes reported in clinical trials can hinder the comparison of clinical trial findings in systematic reviews. Moreover, the outcomes that matter most to older patients might be under-reported or disregarded altogether. A core outcome set can address this issue as it defines a minimum set of outcomes that should be reported in all clinical trials in any particular field of research. As part of the European Commission-funded project, called OPtimising thERapy to prevent Avoidable hospital admissions in the Multimorbid elderly, this paper describes the methods used to develop a core outcome set for clinical trials of medication review in older patients with multimorbidity. Methods/design: The study was designed in several steps. First, a systematic review established which outcomes were measured in published

  1. Reduction of group A beta-hemolytic streptococcus pharyngo-tonsillar infections associated with use of the oral probiotic Streptococcus salivarius K12: a retrospective observational study

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    Gregori G

    2016-01-01

    Full Text Available Giuseppe Gregori,1 Ornella Righi,1 Paolo Risso,2 Goffreda Boiardi,1 Giovanni Demuru,1 Anna Ferzetti,1 Antonio Galli,1 Marco Ghisoni,1 Sonia Lenzini,1 Claudio Marenghi,1 Caterina Mura,1 Roberto Sacchetti,1 Lucia Suzzani1 1Primary Care Department, Local Health Unit (ASL, Piacenza, 2Department of Health Science (DISSAL, University of Genoa, Genoa, Italy Abstract: Recurrent pharyngo-tonsillar infections caused by group A beta-hemolytic streptococci (GABHS occur frequently in young children, and the treatment of these infections contributes substantially to the total current requirement for antibiotic prescribing. Our study goal was to assess through a retrospective observational analysis whether the administration of the oral probiotic, Streptococcus salivarius K12 (SsK12, could reduce the occurrence of GABHS pharyngo-tonsillar infections in children who had a recent history of recurrent episodes of these infections. Twelve primary care pediatricians identified, through their databases, a total of 130 children who had experienced recurrent GABHS pharyngo-tonsillar infections over a period of at least 6–12 months prior to their inclusion in the study. Of these children, 76 then undertook a 90-day program requiring once-a-day dosing with a commercially available (Bactoblis lozenge containing SsK12. No probiotic supplement was given to the remaining 54 (control children. Each subject was monitored for the occurrence of GABHS pharyngo-tonsillitis and also for acute otitis media, bronchitis, sinusitis, and bronchopneumonia for at least 12 months following their entry to the study. Even 9 months after the use of SsK12 had been stopped, the probability of new GABHS infections was significantly lower (P>0.001 when compared to the period before dosing commenced. When compared to the untreated children, those taking SsK12 appear to have had significantly fewer GABHS infections both during the 90-day period of prophylaxis and during the following 9

  2. Observational evaluation of preoperative, intraoperative, and postoperative characteristics in 117 Brazilian women without uterine prolapse undergoing vaginal hysterectomy

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    Osako MT

    2012-09-01

    Full Text Available Claudio Sergio Batista,1 Takasi Osako,2 Eliana Mara Clemente,2 Fernanda Carvalhido Antonio Batista,3 Maurício Takeshi Janiques Osako41Department of Gynecology and Obstetrics of Faculty of Medicine of Petropolis, Petropolis, Rio de Janeiro, Brazil; 2Gynecology and Obstetrics, Casa Providencia Hospital, Petropolis, Rio de Janeiro, Brazil; 3School of Medicine of Technical Educational Foundation Souza Marques, Rio de Janeiro, Brazil; 4School of Medicine of University Gama Filho, Rio de Janeiro, BrazilBackground: Despite the introduction of minimally invasive approaches for various benign uterine problems, hysterectomy is often still performed abdominally, but the vaginal route should be used whenever possible. The aim of this study was to identify the preoperative, intraoperative, and postoperative characteristics of women undergoing vaginal hysterectomy in the absence of uterine prolapse.Methods: A prospective, descriptive, quantitative, noncomparative study was conducted in 117 women between August 2009 and February 2011 in Petropolis, Rio de Janeiro, Brazil. The women included had a uterine indication for hysterectomy, their surgeries were performed by the same team, and they were followed up for 12 months. An adapted Pelvic Organ Prolapse Quantification system was used to check for uterine prolapse.Results: The age range of the women was 33–59 years, uterine volume was 300–900 mL, and 73.50% has undergone prior cesarean section. The main indication for hysterectomy was uterine myoma (64.95%, with a surgery time of 30–60 minutes in 55 (59.82% and 19 (15.98% cases, respectively. Uterine volume reduction was performed in 41 (35.05% cases, salpingectomy was the most common associated surgery (81.19%, and anesthesia was subdural (68.37%. Common intraoperative complications included bladder lesions (8.54%, with conversion to the abdominal route being necessary in one case (1.28%, and the most common postoperative complication being vaginal

  3. Dose-response curve to salbutamol during acute and chronic treatment with formoterol in COPD

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    La Piana GE

    2011-07-01

    Full Text Available Giuseppe Emanuele La Piana¹, Luciano Corda², Enrica Bertella¹, Luigi Taranto Montemurro¹, Laura Pini¹, Claudio Tantucci¹¹Cattedra di Malattie dell'Apparato Respiratorio, Università di Brescia, ²Prima Divisione di Medicina Interna, Spedali Civili, Brescia, ItalyBackground: Use of short-acting ß2-agonists in chronic obstructive pulmonary disease (COPD during treatment with long-acting ß2-agonists is recommended as needed, but its effectiveness is unclear. The purpose of this study was to assess the additional bronchodilating effect of increasing doses of salbutamol during acute and chronic treatment with formoterol in patients with COPD.Methods: Ten patients with COPD underwent a dose-response curve to salbutamol (until 800 µg of cumulative dose after a 1-week washout (baseline, 8 hours after the first administration of formoterol 12 µg (day 1, and after a 12-week and 24-week period of treatment with formoterol (12 µg twice daily by dry powder inhaler. Peak expiratory flow, forced expiratory volume in one second (FEV1, forced vital capacity, and inspiratory capacity were measured at the different periods of treatment and at different steps of the dose-response curve.Results: Despite acute or chronic administration of formoterol, maximal values of peak expiratory flow, FEV1, and forced vital capacity after 800 µg of salbutamol were unchanged compared with baseline. The baseline FEV1 dose-response curve was steeper than that at day 1, week 12, or week 24 (P < 0.0001. Within each dose-response curve, FEV1 was different only at baseline and at day 1 (P < 0.001, when FEV1 was still greater at 800 µg than at 0 µg (P < 0.02. In contrast, the forced vital capacity dose-response curves were similar at the different periods, while within each dose-response curve, forced vital capacity was different in all instances (P < 0.001, always being higher at 800 µg than at 0 µg (P < 0.05.Conclusion: In patients with stable COPD, the maximal effect

  4. CIL, II²/5, 316 (Igabrum y la cronología de los primeros flamines provinciales de la Bética

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    Goffaux, Bertrand

    2013-12-01

    Full Text Available A new reading is given for the CIL, II²/5, 316 inscription, from Igabrum (Cabra, Córdoba, based on a revision of the manuscript tradition. This manuscript gave the curriculum of a knight from Baetica, who had been praefectus fabrum, then military tribune in the legio VI Victrix, and then magistrate in the colonia Patricia, finally reaching the provincial flaminate. Such a career, including local honores after the sequence praefectura fabrum – military tribunate, is typical of the Augustan and Julio-Claudian period, which leads to a revision of the chronology of the document which could date back to the end of the Julio-Claudians, or the very beginning of the Flavian dynasty. Such a chronology raises questions about the origins of the provincial flaminate of Baetica, and about the commonly-accepted assumption that it was a Flavian creation.A partir de una revisión de la tradición manuscrita, se propone una nueva lectura de la inscripción CIL, II²/5, 316, de Igabrum (Cabra, Córdoba, que se refiere a la carrera de un caballero de la Bética. Su cursus hubiera incluido un nivel local, como magistrado de la colonia Patricia, después del ejercicio de la praefectura fabrum y del tribunado militar de la legio VI Victrix, y antes de su elección al flaminado provincial. La presencia de una función a nivel local, después de la sucesión praefectus fabrum – tribuno militar, es típica de los tiempos de Augusto o de los Julio-Claudios, y lleva a una revisión de la fecha del documento que podría colocarse al final de la época Julio-Claudia, o muy temprano en la época Flavia. Esta nueva cronología requiere interrogarse acerca de los orígenes del flaminado provincial de la Bética, y volver a examinar los criterios que llevaron a situar su creación bajo los emperadores Flavios.

  5. Efficacy of CR4056, a first-in-class imidazoline-2 analgesic drug, in comparison with naproxen in two rat models of osteoarthritis

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    Comi E

    2017-05-01

    Full Text Available Eleonora Comi,1,2 Marco Lanza,1 Flora Ferrari,1 Valeria Mauri,1,3 Gianfranco Caselli,1 Lucio Claudio Rovati1 1Department of Pharmacology and Toxicology, Rottapharm Biotech, 2PhD Program in Neuroscience, University of Milan-Bicocca, 3Department of Surgery and Translational Medicine, University of Milan-Bicocca, Monza, Italy Purpose: CR4056, (2-phenyl-6-(1H-imidazol-1yl quinazoline, an imidazoline-2 (I2 receptor ligand, is a promising analgesic drug that has been reported to be effective in several animal models of pain. The aim of this study was to evaluate the effects of CR4056 in two well-established rat models of osteoarthritis (OA, mimicking the painful and structural components of human OA.Methods: Knee OA was induced either by single intra-articular injection of monoiodoacetate (MIA or by medial meniscal tear (MMT in the right knee of male rats. In the MIA model, allodynia and hyperalgesia were measured as paw withdrawal threshold to mechanical stimulation. In the MMT model, pain behavior was analyzed as weight-bearing asymmetry (i.e. difference in hind paw weight distribution, HPWD between the injured and the contralateral limbs.Results: Acute oral administration of CR4056, 14 days after MIA injection, significantly and dose-dependently reduced allodynia and hyperalgesia 90 minutes after treatment, whereas acute naproxen administration significantly reduced allodynia but not hyperalgesia. After 7 days of repeated treatment, both CR4056 and naproxen showed significant anti-allodynic and anti-hyperalgesic effects in the MIA model. Rats undergoing MMT surgery developed a significant and progressive asymmetry in HPWD compared with sham-operated animals. Repeated treatment with CR4056 significantly reduced the progression of the pain behavior, whereas naproxen had no effects.Conclusion: The data presented here show that the I2 ligand CR4056 could be a new effective treatment for OA pain. The compound is currently under Phase II clinical

  6. Surgery in asymptomatic patients with colorectal cancer and unresectable liver metastases: the authors' experience

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    Boselli C

    2013-03-01

    Full Text Available Carlo Boselli,1 Claudio Renzi,2 Alessandro Gemini,1 Elisa Castellani,1 Stefano Trastulli,2 Jacopo Desiderio,2 Alessia Corsi,2 Francesco Barberini,1 Roberto Cirocchi,2 Alberto Santoro,3 Amilcare Parisi,4 Adriano Redler,3 Giuseppe Noya1 1Department of General and Oncologic Surgery, University of Perugia, Perugia, 2Department of General Surgery, University of Perugia, St Maria Hospital, Terni, 3Department of Surgical Sciences, Sapienza University of Rome, Rome, 4Department of Digestive Surgery, St Maria Hospital, Terni, Italy Purpose: In asymptomatic patients with Stage IV colorectal cancer, the debate continues over the efficacy of primary resection compared to chemotherapy alone. The aim of this study was to define the optimal management for asymptomatic patients with colorectal cancer and unresectable liver metastases. Patients and methods: Patients receiving elective surgery (n = 17 were compared to patients receiving chemotherapy only (n = 31. Data concerning patients' demographics, location of primary tumor, comorbidities, performance status, Child–Pugh score, extension of liver metastases, size of primary, and other secondary locations were collected. Results: Thirty-day mortality after chemotherapy was lower than that after surgical resection (19.3% versus 29.4%; not significant. In patients with >75% hepatic involvement, mortality at 1 month was higher after receiving surgical treatment than after chemotherapy alone (50% versus 25%. In patients with <75% hepatic involvement, 30-day mortality was similar in both groups (not significant. Thirty-day mortality in patients with Stage T3 was lower in those receiving chemotherapy (16.7% versus 30%; not significant. Overall survival was similar in both groups. The risk of all-cause death after elective surgery (2.1 was significantly higher than in patients receiving chemotherapy only (P = 0.035. Conclusion: This study demonstrated that in palliative treatment of asymptomatic unresectable Stage

  7. Resistance training associated with the administration of anabolic-androgenic steroids improves insulin sensitivity in ovariectomized rats

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    Urtado CB

    2011-11-01

    Full Text Available Christiano Bertoldo Urtado1,2, Guilherme Borges Pereira3, Marilia Bertoldo Urtado4, Érica Blascovi de Carvalho2, Gerson dos Santos Leite1, Felipe Fedrizzi Donatto1, Claudio de Oliveira Assumpção1, Richard Diego Leite3, Carlos Alberto da Silva1, Marcelo Magalhães de Sales5, Ramires Alsamir Tibana5, Silvia Cristina Crepaldi Alves1, Jonato Prestes51Health Sciences, Methodist University of Piracicaba, Piracicaba, SP, 2Center for Investigation in Pediatrics, Faculty of Medical Sciences, State University of Campinas, Campinas, SP, 3Department of Physiological Sciences, Federal University of São Carlos, São Carlos, SP, 4Laboratory of Orofacial Pain, Division of Oral Physiology, Piracicaba Dental School, State University of Campinas, Campinas, SP, 5Graduation Program in Physical Education, Catholic University of Brasilia, Brasilia, DF, BrazilAbstract: The aim of the present study was to investigate the effects of anabolic-androgenic steroids and resistance training (RT on insulin sensitivity in ovariectomized rats. Adult female Wistar rats were divided into ten experimental groups (n = 5 animals per group: (1 sedentary (Sed-Intact; (2 sedentary ovariectomized (Sed-Ovx; (3 sedentary nandrolone (Sed-Intact-ND; (4 sedentary ovariectomized plus nandrolone (Sed-Ovx-ND; (5 trained (TR-Intact; (6 trained nandrolone (TR-Intact-ND; (7 trained ovariectomized (TR-Ovx; (8 trained ovariectomized plus nandrolone; (9 trained sham; and (10 trained ovariectomized plus sham. Four sessions of RT were used, during which the animals climbed a 1.1 m vertical ladder with weights attached to their tails. The sessions were performed once every 3 days, with between four and nine climbs and with eight to twelve dynamic movements per climb. To test the sensitivity of insulin in the pancreas, glucose and insulin tolerance tests were performed. For insulin sensitivity, there was a statistically significant interaction for the TR-Ovx group, which presented higher sensitivity

  8. Antineoplastic-related cardiotoxicity, morphofunctional aspects in a murine model: contribution of the new tool 2D-speckle tracking

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    Coppola C

    2016-11-01

    Full Text Available Carmela Coppola,1 Gennaro Riccio,1 Antonio Barbieri,2 Maria Gaia Monti,3 Giovanna Piscopo,1 Domenica Rea,2 Claudio Arra,2 Carlo Maurea,1 Claudia De Lorenzo,4,5 Nicola Maurea1 1Division of Cardiology, Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione G. Pascale”, IRCCS, Naples, Italy; 2Animal Facility Unit, Department of Experimental Oncology, Istituto Nazionale per lo Studio e la Cura dei Tumori “Fondazione G. Pascale”, IRCCS, Naples, Italy; 3Department of Translational Medical Sciences, University Federico II, Naples, Italy; 4Department of Molecular Medicine and Medical Biotechnology, University Federico II, Naples, Italy; 5CEINGE Biotecnologie Avanzate, Naples, Italy Objective: Considering that global left ventricular systolic radial strain is a sensitive technique for the early detection of left ventricular dysfunction due to antineoplastics and the analysis of segmental myocardial contractility, we evaluated this technique for early detection of trastuzumab-related cardiotoxicity by comparing it with cardiac structural damage.Methods: Groups of six mice were injected with trastuzumab or doxorubicin, used either as single agents or in combination. Cardiac function was evaluated by transthoracic echocardiography measurements before and after treatment for 2 or 7 days, by using a Vevo 2100 high-resolution imaging system. After echocardiography, mice were euthanized, and hearts were processed for histological evaluations, such as cardiac fibrosis, apoptosis, capillary density, and inflammatory response.Results: Trastuzumab-related cardiotoxicity was detected early by 2D strain imaging. Radial strain was reduced after 2 days in mice treated with trastuzumab alone (21.2%±8.0% vs 40.5%±4.8% sham; P<0.01. Similarly, trastuzumab was found to induce apoptosis, capillary density reduction, and inflammatory response in cardiac tissue after 2 days of treatment, in a fashion similar to doxorubicin. On the contrary, fractional

  9. [The Origin of Scientific Notions in the Circle of the Roman Accademiadella Virt¾ around 1550].

    Science.gov (United States)

    Kulawik, Bernd

    2015-06-01

    The Origin of Scientific Notions in the Circle of the Roman Accademia della Virtù around 1550. Between c. 1537 and 1555 a group of humanists, clerics, architects and philologists known as the so-called Accademia della Virtù got together in Rome to work on a program which was formulated in a letter by the Sienese humanist Claudio Tolomei in 1542 and published in 1547. Starting out with the intention to understand the only surviving antique book on architecture and architectural theory - Vitruvius' De architectura libri decem - the program describes a series of 24 books, eleven containing the classical text and its translation with commentaries, 13 books systematically illustrating and documenting all known and available material remains from Roman antiquity. This program for a scientific classical archaeology in a modern sense was not only intended to serve the intellectual curiosity of some humanist antiquarians but to help architects and their patrons to develop a new architecture of the same high quality as the idealized Roman examples. To achieve this practical as well as theoretical goal it was obviously necessary to re-create the antique vocabulary of architecture and its rules as well as to unify the contemporary usage of notions and norms in a canon. The first results of this project seem to be the In decem Libros M. Vitruvii Pollionis de Architectura Annotationes by Guillaume Philandrier (Rome, 1544) - up to this day a very valuable explanation of ambiguous parts in the Vitruvian text. Until the 1980s, it was believed that this book was the only outcome of the ambitious project; but then two codices of drawings after antique reliefs were identified as preparations for one of the other 23 volumes - and, because of their systematic approach, regarded as the 'first systematic archaeological book'. Now it seems that there are some other corpora of manuscripts and drawings documenting antique artifacts that should be regarded as results of the Accademia's work

  10. Inhalation errors due to device switch in patients with chronic obstructive pulmonary disease and asthma: critical health and economic issues

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    Roggeri A

    2016-03-01

    Full Text Available Alessandro Roggeri,1 Claudio Micheletto,2 Daniela Paola Roggeri1 1ProCure Solutions, Nembro, Bergamo, Italy, 2Respiratory Unit, Mater Salutis Hospital, Legnago, Verona, Italy Background: Different inhalation devices are characterized by different techniques of use. The untrained switching of device in chronic obstructive pulmonary disease (COPD and asthma patients may be associated with inadequate inhalation technique and, consequently, could lead to a reduction in adherence to treatment and limit control of the disease. The aim of this analysis was to estimate the potential economic impact related to errors in inhalation in patients switching device without adequate training. Methods: An Italian real-practice study conducted in patients affected by COPD and asthma has shown an increase in health care resource consumption associated with misuse of inhalers. Particularly, significantly higher rates of hospitalizations, emergency room visits (ER, and pharmacological treatments (steroids and antimicrobials were observed. In this analysis, those differences in resource consumption were monetized considering the Italian National Health Service (INHS perspective. Results: Comparing a hypothetical cohort of 100 COPD patients with at least a critical error in inhalation vs 100 COPD patients without errors in inhalation, a yearly excess of 11.5 hospitalizations, 13 ER visits, 19.5 antimicrobial courses, and 47 corticosteroid courses for the first population were revealed. In the same way, considering 100 asthma patients with at least a critical error in inhalation vs 100 asthma patients without errors in inhalation, the first population is associated with a yearly excess of 19 hospitalizations, 26.5 ER visits, 4.5 antimicrobial courses, and 21.5 corticosteroid courses. These differences in resource consumption could be associated with an increase in health care expenditure for INHS, due to inhalation errors, of €23,444/yr in COPD and €44,104/yr in

  11. The role of health technology assessment bodies in shaping drug development

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    Ciani O

    2014-11-01

    Full Text Available Oriana Ciani,1,3 Claudio Jommi1,2 1Centre for Research on Health and Social Care Management (CERGAS, Bocconi University, Milan, Italy; 2Department of Pharmaceutical Sciences, Università del Piemonte Orientale, Novara, Italy; 3University of Exeter Medical School, Exeter, UK Abstract: The use of health technology assessment (HTA to inform policy-making is established in most developed countries. Compared to licensing agencies, HTA agencies have different interests and, therefore, different evidence requirements. Criteria for coverage or reimbursement decisions on pharmaceutical compounds vary; however, it is common to include, as part of the HTA, a comparative effectiveness evaluation. This type of clinical data might go beyond that required for market authorization, thus creating an additional evidence gap between the regulatory and the reimbursement submission. The relevance of submissions to HTA agencies is consistently increasing in a pharmaceutical company’s perspective, as market prospects are strongly influenced by third-party payers’ coverage. In this study, we aim to describe current HTA activities with a potential impact throughout the drug development process of pharmaceuticals, with a comparative emphasis on the systems in place in Italy and in the UK. Based on an extensive literature and website review, we identified three major classes of HTA activities, beyond mainstream HTA, with the potential to influence the drug development program: 1 horizon scanning and early HTA; 2 bipartite and tripartite early dialogue between manufacturers, regulators, and HTA assessors; and 3 managed market entry agreements. From early stages of clinical research up to postauthorization studies, there is a trend toward increased collaboration between parties, anticipation of market access evidence collection, and postmarketing risk-sharing. Heterogeneity of HTA practices increases the complexity of the market access environment. Overall, there are

  12. Fat-free mass change after nutritional rehabilitation in weight losing COPD: role of insulin, C-reactive protein and tissue hypoxia

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    Simonetta Baldi

    2010-02-01

    Full Text Available Simonetta Baldi, Roberto Aquilani, Gian Domenico Pinna, Paolo Poggi, Angelo De Martini, Claudio BruschiDepartment of Pneumology and Biomedical Engineering, Scientific Institute of Montescano, Salvatore Maugeri Foundation I.R.C.C.S. Pavia, ItalyBackground: Fat-free mass (FFM depletion marks the imbalance between tissue protein synthesis and breakdown in chronic obstructive pulmonary disease (COPD. To date, the role of essential amino acid supplementation (EAAs in FFM repletion has not been fully acknowledged. A pilot study was undertaken in patients attending pulmonary rehabilitation.Methods: 28 COPD patients with dynamic weight loss > 5% over the last 6 months were randomized to receive EAAs embedded in a 12-week rehabilitation program (EAAs group n = 14, or to the same program without supplementation (C group n = 14. Primary outcome measures were changes in body weight and FFM, using dual X-ray absorptiometry (DEXA.Results: At the 12th week, a body weight increment occurred in 92% and 15% of patients in the EAAs and C group, respectively, with an average increase of 3.8 ± 2.6 kg (P = 0.0002 and −0.1 ± 1.1 kg (P = 0.81, respectively. A FFM increment occurred in 69% and 15% of EAAs and C patients, respectively, with an average increase of 1.5 ± 2.6 kg (P = 0.05 and −0.1 ± 2.3 kg (P = 0.94, respectively. In the EAAs group, FFM change was significantly related to fasting insulin (r2 0.68, P < 0.0005, C-reactive protein (C-RP (r2 = 0.46, P < 0.01, and oxygen extraction tension (PaO2x (r2 = 0.46, P < 0.01 at end of treatment. These three variables were highly correlated in both groups (r > 0.7, P < 0.005 in all tests.Conclusions: Changes in FFM promoted by EAAs are related to cellular energy and tissue oxygen availability in depleted COPD. Insulin, C-RP, and PaO2x must be regarded as clinical markers of an amino acid-stimulated signaling to FFM accretion.Keywords: COPD, pulmonary rehabilitation, branched chain amino acids, insulin, systemic

  13. Symptomatic or prophylactic treatment of weekend migraine: an open-label, nonrandomized, comparison study of frovatriptan versus naproxen sodium versus no therapy

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    Guidotti M

    2013-01-01

    Full Text Available Mario Guidotti,1 Caterina Barrilà,1 Serena Leva,1 Claudio De Piazza,1 Stefano Omboni21Department of Neurology, Valduce Hospital, Como, 2Italian Institute of Telemedicine, Varese, ItalyBackground: Migraine often occurs during weekends. The efficacy of frovatriptan, naproxen sodium, or no therapy for the acute or prophylactic treatment of weekend migraineurs was tested in an open-label, nonrandomized pilot study.Methods: Twenty-eight subjects (mean age 36 ± 12 years, including 18 females suffering from migraine without aura were followed up for six consecutive weekends. No treatment was administered during the first two weekends. On the third and fourth weekends, patients were given frovatriptan 2.5 mg and on the fifth and sixth weekends naproxen sodium 500 mg. Treatment was taken on Saturday and Sunday morning, regardless of the occurrence of migraine. Efficacy was evaluated through a diary, where patients reported the severity of migraine on a scale from 0 (no migraine to 10 (severe migraine and use of rescue medication.Results: The migraine severity score was significantly lower with frovatriptan (4.8 [95% confidence interval (CI 3.8–5.9] than with naproxen sodium (5.7 [CI 5.1–6.4], P < 0.05 versus frovatriptan or no therapy (6.6 [6.2–7.0], P < 0.01 versus frovatriptan. The difference in favor of frovatriptan was more striking in patients not taking rescue medication (frovatriptan, 1.9 [1.5–2.3] versus naproxen sodium 3.6 [3.0–4.2], P < 0.001 and versus no therapy (5.1 [4.4–5.8], P < 0.001 and on the second day of treatment. The rate of use of rescue medication was significantly (P < 0.05 lower on frovatriptan (12.5% than on naproxen sodium (31.3% or no therapy (56.3%.Conclusion: This pilot study provides the first evidence of the efficacy of a second-generation triptan as symptomatic or prophylactic treatment for weekend migraine.Keywords: migraine, frovatriptan, naproxen sodium, weekend

  14. Campo Belo Metamorphic Complex: tectonic evolution of an Archean sialic crust of the southern São Francisco Craton in Minas Gerais (Brazil

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    ARILDO H. OLIVEIRA

    2001-09-01

    Full Text Available Systematic geological studies performed in the study area allowed the characterization of six lithodemic units: three gneissic, one amphibolitic, one supracrustal and one fissure mafic. The mineral assemblage and the structural record of these lithodemic units indicate that the study area was affected by five tectonothermal events. The structural pattern of the first and oldest event occurred under granulite facies conditions and reveals essentially a sinistral kinematic pattern. The second event, showing dominant extensional characteristics, is related to the generation of an ensialic basin filled by the volcano-sedimentary sequence of the supracrustal lithodemic unit. The third event, which is the most expressive in the study region, is characterized by a vigorous regional migmatization process and by the generation of the Claudio Shear Zone, presenting dextral kinematic movement. The fourth event is represented by a fissure mafic magmatism (probably two different mafic dike swarms and finally, the fifth event is a regional metamorphic re-equilibration that reached the greenschist facies, closing the main processes of the tectonic evolution of the Campo Belo Metamorphic Complex.Estudos geológicos sistemáticos permitiram a caracterização de seis unidades litodêmicas na área estudada: três gnáissicas, uma anfibolítica, uma supracrustal e uma máfica fissural. A assembléia mineral e os registros estruturais dessas unidades litodêmicas mostraram que a área estudada foi afetada por cinco eventos tectonotermais. O padrão estrutural do primeiro e último evento ocorreu em condições de fácies granulito e revelaram uma cinemática essencialmente sinistral. O segundo evento mostrou uma tectônica extensional relacionado à abertura da bacia ensiálica onde se alojou a seqüência vulcanosedimentar da unidade supracrustal. O terceiro evento, que é o mais expressivo na região estudada, é o responsável por um intenso processo de

  15. The complex of PAMAM-OH dendrimer with Angiotensin (1–7 prevented the disuse-induced skeletal muscle atrophy in mice

    Directory of Open Access Journals (Sweden)

    Márquez-Miranda V

    2017-03-01

    Full Text Available Valeria Márquez-Miranda,1,2,* Johanna Abrigo,3,4,* Juan Carlos Rivera,3,4 Ingrid Araya-Durán,1 Javier Aravena,3,4 Felipe Simon,3,4 Nicolás Pacheco,1 Fernando Danilo González-Nilo,1,2,5 Claudio Cabello-Verrugio3,4 1Center for Bioinformatics and Integrative Biology (CBIB, Facultad de Ciencias Biologicas, Universidad Andres Bello, Santiago, 2Fundación Fraunhofer Chile Research, Las Condes, 3Departamento de Ciencias Biologicas, Facultad de Ciencias Biologicas & Facultad de Medicina, Universidad Andres Bello, 4Millennium Institute on Immunology and Immunotherapy, Santiago, 5Centro Interdisciplinario de Neurociencia de Valparaíso, Facultad de Ciencias, Universidad de Valparaíso, Valparaíso, Chile *These authors contributed equally to this work Abstract: Angiotensin (1–7 (Ang-(1–7 is a bioactive heptapeptide with a short half-life and has beneficial effects in several tissues – among them, skeletal muscle – by preventing muscle atrophy. Dendrimers are promising vehicles for the protection and transport of numerous bioactive molecules. This work explored the use of a neutral, non-cytotoxic hydroxyl-terminated poly(amidoamine (PAMAM-OH dendrimer as an Ang-(1–7 carrier. Bioinformatics analysis showed that the Ang-(1–7-binding capacity of the dendrimer presented a 2:1 molar ratio. Molecular dynamics simulation analysis revealed the capacity of neutral PAMAM-OH to protect Ang-(1–7 and form stable complexes. The peptide coverage ability of the dendrimer was between ~50% and 65%. Furthermore, an electrophoretic mobility shift assay demonstrated that neutral PAMAM-OH effectively bonded peptides. Experimental results showed that the Ang-(1–7/PAMAM-OH complex, but not Ang-(1–7 alone, had an anti-atrophic effect when administered intraperitoneally, as evaluated by muscle strength, fiber diameter, myofibrillar protein levels, and atrogin-1 and MuRF-1 expressions. The results of the Ang-(1–7/PAMAM-OH complex being intraperitoneally

  16. Quantum Structure of Space and Time

    Science.gov (United States)

    Duff, M. J.; Isham, C. J.

    2012-07-01

    Foreword Abdus Salam; Preface; List of participants; Part I. Quantum Gravity, Fields and Topology: 1. Some remarks on gravity and quantum mechanics Roger Penrose; 2. An experimental test of quantum gravity Don N. Page and C. D. Geilker; 3. Quantum mechanical origin of the sandwich theorem in classical gravitation theory Claudio Teitelboim; 4. θ-States induced by the diffeomorphism group in canonically quantized gravity C. J. Isham; 5. Strong coupling quantum gravity: an introduction Martin Pilati; 6. Quantizing fourth order gravity theories S. M. Christensen; 7. Green's functions, states and renormalisation M. R. Brown and A. C. Ottewill; 8. Introduction to quantum regge calculus Martin Roček and Ruth Williams; 9. Spontaneous symmetry breaking in curved space-time D. J. Toms; 10. Spontaneous symmetry breaking near a black hole M. S. Fawcett and B. F. Whiting; 11. Yang-Mills vacua in a general three-space G. Kunstatter; 12. Fermion fractionization in physics R. Jackiw; Part II. Supergravity: 13. The new minimal formulation of N=1 supergravity and its tensor calculus M. F. Sohnius and P. C. West; 14. A new deteriorated energy-momentum tensor M. J. Duff and P. K. Townsend; 15. Off-shell N=2 and N=4 supergravity in five dimensions P. Howe; 16. Supergravity in high dimensions P. van Niewenhuizen; 17. Building linearised extended supergravities J. G. Taylor; 18. (Super)gravity in the complex angular momentum plane M. T. Grisaru; 19. The multiplet structure of solitons in the O(2) supergravity theory G. W. Gibbons; 20. Ultra-violet properties of supersymmetric gauge theory S. Ferrara; 21. Extended supercurrents and the ultra-violet finiteness of N=4 supersymmetric Yang-Mills theories K. S. Stelle; 22. Duality rotations B. Zumino; Part III. Cosmology and the Early Universe: 23. Energy, stability and cosmological constant S. Deser; 24. Phase transitions in the early universe T. W. B. Kibble; 25. Complete cosmological theories L. P. Grishchuk and Ya. B. Zeldovich; 26. The

  17. Pregnancy is associated with psychiatric symptoms in a low-income countryside community of Brazil

    Directory of Open Access Journals (Sweden)

    Dias FMV

    2011-11-01

    Full Text Available Fernando MV Dias1–3, Claudio SD Junior4, Glaura C Franco5, Antônio L Teixeira3, Angela M Ribeiro21Department of Medicine and Nursing, Federal University of Viçosa, Viçosa; 2Graduate Program in Neurosciences, Laboratory of Molecular and Behavioral Neuroscience (LaNeC; 3Graduate Program in Neurosciences, Neuropsychiatric Branch Research; 4Department of Sociology and Anthropology; 5Department of Statistics, Federal University of Minas Gerais, Belo Horrizonte, BrazilBackground: Psychiatric symptoms during pregnancy induce an increase in morbidity and also in the mortality levels among women and children. However, the real association between pregnancy and psychiatric disorders and the peculiarities of the phenomenology of symptoms in underprivileged countryside communities remain uncertain.Objective: To verify the association between psychiatric disorder, symptoms, and pregnancy among women from a low-income countryside community and to determine the specific cutoff points for major depression diagnosis according to Beck Depression Inventory for the different trimesters of pregnancy in this population.Methods: Ninety-four pregnant women and 38 healthy women from the Conceição do Mato Dentro health service, a rural low-income community in Brazil, participated in the present study. Psychiatric examination included a structured clinical interview for psychiatric disorders according to Mini International Neuropsychiatric Interview and psychometric scales such as the Yale–Brown Obsessive Scale, the Beck Depression Inventory, and the Hamilton Anxiety Scale. The cutoff points for Beck Depression Inventory were determined through the application of receiver operating characteristic curves considering the diagnosis of major depression according to Mini International Neuropsychiatric Interview.Results: The pregnant women had a higher frequency of psychiatric disorders and depression and anxiety symptoms. All cutoff points of Beck Depression Inventory

  18. Apariencia y realidad en Hamlet y Las Meninas

    Directory of Open Access Journals (Sweden)

    Antonio PRIETO MARTÍNEZ

    2009-11-01

    Full Text Available La obra de Shakespeare comenzó a ser estudiada en profundidad a finales del siglo XVII y, sobre todo, en el siglo XVIII. Desde ese siglo hasta el momento actual la investigación en torno a la obra shakesperiana se ha desarrollado hasta tal punto que resulta inabordable. De entre la obra de Shakespeare, Hamlet es probablemente la que suscita mayor interés a causa de su compleja estructura y su contenido ambiguo. Del mismo modo, la obra de Velázquez comenzó a estudiarse con rigor en el siglo XVIII, aunque hasta el siglo XX no se investigan sus características e influencias. Como en el caso de Shakespeare, la bibliografía existente en la actualidad sobre su obra resulta inaccesible para el investigador. De entre todas sus pinturas, Las Meninas, del mismo modo que Hamlet, es la que despierta mayor interés y tiene una proyección universal. Haciendo un recorrido por las investigaciones más importantes realizadas sobre ambas obras en los tres últimos siglos, intento encontrar semejanzas entre ellas, basándome fundamentalmente en su estructura. Apoyando mi investigación en la teoría deconstructivista, según la propuesta de J. Derrida, y siguiendo el esquema formal de ambas obras, propongo el tema general de apariencia y realidad como núcleo de sus semejanzas. Los puntos de analogía entre Hamlet y Las Meninas son, en síntesis, los siguientes: - Texto (expresado en el ser o no ser y el reverso del lienzo sobre el que pinta Velázquez. - El personaje del espectro en Hamlet y el personaje invisible en el cuadro (María Teresa de Austria o el espectador. - Velázquez significante representado en el cuadro y la obra dentro de la obra que representan los cómicos. - El personaje de Claudio, como símbolo del tirano y los reyes representados en el espejo. - Finalmente considero la vigencia y proyección que tienen ambas obras en el mundo actual.

  19. Book Reviews

    Directory of Open Access Journals (Sweden)

    Redactie KITLV

    2008-12-01

    Full Text Available Christoph Antons (ed.; Law and development in East and South-East Asia (Adriaan Bedner David B. Dewitt, Carolina G. Hernandez (eds; Development and security in Southeast Asia (vol. 1 & 2 (Freek Colombijn Lily Kong, Brenda S.A. Yeoh; The politics of landscape in Singapore; Constructions of ‘nation’ (Ben Derudder Andrew Hardy; Red hills; Migrants and the state in the highlands of Vietnam (Hans Hägerdal Hanneman Samuel, Henk Schulte Nordholt (eds; Indonesia in transition; Rethinking ‘civil society’, ‘region’, and ‘crisis’ (david Henley S. Margana; Pujangga Jawa dan bayang-bayang kolonial (Mason Hoadley Karel E.M. Bongenaar; De ontwikkeling van het zelfbesturend landschap in Nederlandsch-Indie: 1855-1942 (Gerry van Klinken Pamela J. Stewart, Andrew Strathern; Humors and substances; Ideas of the body in New Guinea (Michael Lieber Wu Xiao An; Chinese business in the making of a Malay state, 1882-1941 (Loh Wei Leng Mikihiro Moriyama; Sundanese print culture and modernity in 19th-century West Java (Julian Millie Yunita T. Winarto; Seeds of knowledge; The beginning of integrated pest management in Java (Simon Platten Jelle Miedema, Ger Reesink; One head, many faces; New perspectives on the Bird’s Head Peninsula of New Guinea (Anton Ploeg Christopher R. Duncan (ed.; Civilizing the margins; Southeast Asian government policies for the development of minorities (Nathan Porath Rosario Mendoza Cortes, Celestina Puyal Boncan, Ricardo Trota Jose; The Filipino saga; History as social change (Portia L. Reyes Stephen Dobbs; The Singapore River; A social history, 1819-2002 (Victor R. Savage Michael Wood; Official history in modern Indonesia; New Order perceptions and counterviews (Henk Schulte Nordholt Claudio O. Delang (ed.; Living at the edge of Thai society; The Karen in the highlands of northern Thailand (Nicholas Tapp Andrew C. Willford, Kenneth M. George (eds; Spirited politics: Religion

  20. A cost-effectiveness evaluation comparing originator follitropin alfa to the biosimilar for the treatment of infertility

    Directory of Open Access Journals (Sweden)

    Gizzo S

    2016-12-01

    Full Text Available Salvatore Gizzo,1 Juan A Garcia-Velasco,2 Franca Heiman,3 Claudio Ripellino,3 Klaus Bühler4 1Department of Woman and Child Health, University of Padua, Padua, Italy; 2Department of Obstetrics and Gynecology, Rey Juan Carlos University Madrid, Madrid, Spain; 3IMS Health Information Solutions Italy Srl, Milan, Italy; 4Centre for Gynaecology, Endocrinology, and Reproductive Medicine, Ulm and Stuttgart, Germany Objectives: To perform a cost-effectiveness evaluation comparing the originator follitropin alfa (Gonal-f® to the biosimilar (Bemfola® in the Italian and Spanish contexts, with an assessment of the German and UK backgrounds. Methods: Starting from the study by Rettenbacher et al, a cost-effectiveness model was developed in the Italian and Spanish contexts. Clinical data on subjects, doses of gonadotropin, pregnancies, live-born children, and ovarian hyperstimulation syndrome were used to feed the model. Costs related to drugs, hospitalizations, specialist visits, and examinations were retrieved from Italian and Spanish tariffs. Gonadotropin acquisition costs for Germany and the UK were also taken into account to expand the economical assessment to the other countries. The evaluation was done based on the National Health Service perspective. Sensitivity analyses, both univariate and probabilistic, as long as scenario analyses, tested the robustness of the model. Results: Originator follicle-stimulating hormone (FSH costs were €3,663 and €6,387 in Italy and Spain, respectively, whereas biosimilar FSH costs were €3,483 and €6,342. The efficacy was found to be 0.52 for the originator and 0.47 for the biosimilar. The average cost per live birth was estimated to be €7,044 and €12,283 for the originator FSH and €7,411 and €13,494 for the biosimilar for Italy and Spain, respectively. Furthermore, the originator FSH generated an incremental cost-effectiveness ratio of €3,600 for Italy and €900 for Spain compared to the

  1. Low-dose modified-release prednisone in axial spondyloarthritis: 3-month efficacy and tolerability

    Directory of Open Access Journals (Sweden)

    Bandinelli F

    2016-11-01

    Full Text Available Francesca Bandinelli,1 Francesco Scazzariello,1 Emanuela Pimenta da Fonseca,2 Mittermayer Barreto Santiago,2 Claudio Marcassa,3 Francesca Nacci,1 Marco Matucci Cerinic1 1Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy; 2Service of Rheumatology, Hospital Santa Isabel, Escola de Medicina e Saúde Pública, Bahia, Brazil; 3Maugeri Clinical and Scientific Institutes, IRCCS, Veruno, Novara, Italy Background: Oral glucocorticoids (GCs have been shown to be effective in reducing the inflammatory symptoms of rheumatoid arthritis, but their use is not supported by evidence in spondyloarthritis (SpA. Modified-release (MR oral prednisone taken at bedtime has been shown to be more effective than immediate-release prednisone taken in the morning. The efficacy of low-dose MR prednisolone in patients with SpA is unknown. Patients and methods: This single-center cohort study retrospectively assessed the effectiveness and safety of 12-week low-dose MR prednisone (5 mg daily, bedtime administration in GC-naïve adult patients with symptomatic axial SpA. A 50% improvement of the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI or a final BASDAI score of <4 according to disease activity at baseline was chosen as the primary outcome parameter after MR prednisone. Results: Fifty-seven patients were evaluated; of them, 41 had an active disease (BASDAI score of ≥4 at baseline. MR prednisone significantly reduced BASDAI (from 5.5±2.6 to 3.0±2.8, P<0.001 as well as inflammatory symptoms, pain, fatigue and morning stiffness. The overall response rate after MR prednisone was 52.6% (53.7% in patients with active SpA and 50.0% in patients with low-active disease; nonsignificant. At multivariable analysis, none of the considered clinical findings independently predicted the response to MR prednisone in subjects with active SpA. Overall, seven patients (11.8% had nonserious adverse drug reactions after MR prednisone

  2. Targeted tumor imaging of anti-CD20-polymeric nanoparticles developed for the diagnosis of B-cell malignancies

    Directory of Open Access Journals (Sweden)

    Capolla S

    2015-06-01

    Full Text Available Sara Capolla,1 Chiara Garrovo,2 Sonia Zorzet,1 Andrea Lorenzon,3 Enrico Rampazzo,4 Ruben Spretz,5 Gabriele Pozzato,6 Luis Núñez,7 Claudio Tripodo,8 Paolo Macor,1,9 Stefania Biffi2 1Department of Life Sciences, University of Trieste, 2Institute for Maternal and Child Health – IRCCS “Burlo Garofolo”, Trieste, 3Animal Care Unit, Cluster in Biomedicine (CBM scrl, Trieste, Italy; 4Department of Chemistry “G. Ciamician”, University of Bologna, Bologna, Italy; 5LNK Chemsolutions LLC, Lincoln, NE, USA; 6Department of Medical, Surgery and Health Sciences, University of Trieste, Trieste, Italy; 7Bio-Target, Inc., University of Chicago, Chicago, IL, USA; 8Department of Human Pathology, University of Palermo, Palermo, Italy; 9Callerio Foundation Onlus, Institutes of Biological Researches, Trieste, Italy Abstract: The expectations of nanoparticle (NP-based targeted drug delivery systems in cancer, when compared with convectional therapeutic methods, are greater efficacy and reduced drug side effects due to specific cellular-level interactions. However, there are conflicting literature reports on enhanced tumor accumulation of targeted NPs, which is essential for translating their applications as improved drug-delivery systems and contrast agents in cancer imaging. In this study, we characterized biodegradable NPs conjugated with an anti-CD20 antibody for in vivo imaging and drug delivery onto tumor cells. NPs’ binding specificity mediated by anti-CD20 antibody was evaluated on MEC1 cells and chronic lymphocytic leukemia patients’ cells. The whole-body distribution of untargeted NPs and anti-CD20 NPs were compared by time-domain optical imaging in a localized human/mouse model of B-cell malignancy. These studies provided evidence that NPs’ functionalization by an anti-CD20 antibody improves tumor pharmacokinetic profiles in vivo after systemic administration and increases in vivo imaging of tumor mass compared to non-targeted NPs. Together

  3. The effect of vagal nerve blockade using electrical impulses on glucose metabolism in nondiabetic subjects

    Directory of Open Access Journals (Sweden)

    Sathananthan M

    2014-07-01

    Full Text Available Matheni Sathananthan,1 Sayeed Ikramuddin,2 James M Swain,3,6 Meera Shah,1 Francesca Piccinini,4 Chiara Dalla Man,4 Claudio Cobelli,4 Robert A Rizza,1 Michael Camilleri,5 Adrian Vella1 1Division of Endocrinology, Diabetes and Metabolism, Mayo Clinic College of Medicine, Rochester, MN, USA; 2Division of General Surgery, University of Minnesota, Minneapolis, MN, USA; 3Division of General Surgery, Mayo Clinic College of Medicine, Rochester, MN, USA; 4Department of Information Engineering, University of Padua, Padua, Italy; 5Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, Rochester, MN, USA; 6Scottsdale Healthcare Bariatric Center, Scottsdale, AZ, USA Purpose: Vagal interruption causes weight loss in humans and decreases endogenous glucose production in animals. However, it is unknown if this is due to a direct effect on glucose metabolism. We sought to determine if vagal blockade using electrical impulses alters glucose metabolism in humans. Patients and methods: We utilized a randomized, cross-over study design where participants were studied after 2 weeks of activation or inactivation of vagal nerve blockade (VNB. Seven obese subjects with impaired fasting glucose previously enrolled in a long-term study to examine the effect of VNB on weight took part. We used a standardized triple-tracer mixed meal to enable measurement of the rate of meal appearance, endogenous glucose production, and glucose disappearance. The 550 kcal meal was also labeled with 111In-diethylene triamine pentaacetic acid (DTPA to measure gastrointestinal transit. Insulin action and ß-cell responsivity indices were estimated using the minimal model. Results: Integrated glucose, insulin, and glucagon concentrations did not differ between study days. This was also reflected in a lack of effect on β-cell responsivity and insulin action. Furthermore, fasting and postprandial endogenous glucose production, integrated meal appearance, and glucose

  4. Analgesic effectiveness and tolerability of oral oxycodone/naloxone and pregabalin in patients with lung cancer and neuropathic pain: an observational analysis

    Directory of Open Access Journals (Sweden)

    De Santis S

    2016-07-01

    Full Text Available Stefano De Santis,1 Cristina Borghesi,1 Serena Ricciardi,2 Daniele Giovannoni,1 Alberto Fulvi,2 Maria Rita Migliorino,2 Claudio Marcassa3 1Palliative Care and Cancer Pain Service, Oncological Pulmonary Unit, 2Oncological Pulmonary Unit, San Camillo-Forlanini Hospitals, Rome, 3Cardiologia Fondazione Maugeri IRCCS, Novara, Italy Introduction: Cancer-related pain has a severe negative impact on quality of life. Combination analgesic therapy with oxycodone and pregabalin is effective for treating neuropathic cancer pain. We investigated the efficacy and tolerability of a dose-escalation combination therapy with prolonged-release oxycodone/naloxone (OXN-PR and pregabalin in patients with non-small-cell lung cancer and severe neuropathic pain. Methods: This was a 4-week, open-label, observational study. Patients were treated with OXN-PR and pregabalin. Average pain intensity ([API] measured on a 0–10 numerical rating scale and neuropathic pain (Douleur Neuropathique 4 were assessed at study entry and at follow-up visits. The primary endpoint was response to treatment, defined as a reduction of API at T28 ≥30% from baseline. Secondary endpoints included other efficacy measures, as well as patient satisfaction and quality of life (Brief Pain Inventory Short Form, Hospital Anxiety and Depression Scale, and Symptom Distress Scale; bowel function was also assessed. Results: A total of 56 patients were enrolled. API at baseline was 8.0±0.9, and decreased after 4 weeks by 48% (4.2±1.9; P<0.0001 vs baseline; 46 (82.1% patients responded to treatment. Significant improvements were also reported in number/severity of breakthrough cancer pain episodes (P=0.001, Brief Pain Inventory Short Form (P=0.0002, Symptom Distress Scale (P<0.0001, Hospital Anxiety and Depression Scale depression (P=0.0006 and anxiety (P<0.0001 subscales, and bowel function (P=0.0003. At study end, 37 (66.0% patients were satisfied/very satisfied with the new analgesic treatment

  5. Heart rate response during a simulated Olympic boxing match is predominantly above ventilatory threshold 2: a cross sectional study

    Directory of Open Access Journals (Sweden)

    de Lira CA

    2013-07-01

    Full Text Available Claudio Andre Barbosa de Lira,1 Luiz Fernando Peixinho-Pena,2 Rodrigo Luiz Vancini1,2 Rafael Júlio de Freitas Guina Fachina,3,4 Alexandre Aparecido de Almeida,2 Marília dos Santos Andrade,2 Antonio Carlos da Silva2 1Setor de Fisiologia Humana e do Exercício, Universidade Federal de Goiás (UFG, Câmpus Jataí, Jataí, GO, Brazil; 2Departamento de Fisiologia, Universidade Federal de São Paulo (UNIFESP, São Paulo, SP, Brazil; 3Departamento de Ciência do Esporte, Faculdade de Educação Física (FEF, Universidade Estadual de Campinas (UNICAMP, Campinas, Brazil; 4Confederação Brasileira de Basketball (CBB, Rio de Janeiro, Brazil Abstract: The present study aimed to describe heart rate (HR responses during a simulated Olympic boxing match and examine physiological parameters of boxing athletes. Ten highly trained Olympic boxing athletes (six men and four women performed a maximal graded exercise test on a motorized treadmill to determine maximal oxygen uptake (52.2 mL · kg-1 · min-1 ± 7.2 mL · kg-1 · min-1 and ventilatory thresholds 1 and 2. Ventilatory thresholds 1 and 2 were used to classify the intensity of exercise based on respective HR during a boxing match. In addition, oxygen uptake (VO2 was estimated during the match based on the HR response and the HR-VO2 relationship obtained from a maximal graded exercise test for each participant. On a separate day, participants performed a boxing match lasting three rounds, 2 minutes each, with a 1-minute recovery period between each round, during which HR was measured. In this context, HR and VO2 were above ventilatory threshold 2 during 219.8 seconds ± 67.4 seconds. There was an increase in HR and VO2 as a function of round (round 3 < round 2 < round 1, P < 0.0001.These findings may direct individual training programs for boxing practitioners and other athletes. Keywords: heart rate, physiological profile, intermittent exercise, combat sports, boxing

  6. Ultra-scale Visualization Climate Data Analysis Tools (UV-CDAT)

    Energy Technology Data Exchange (ETDEWEB)

    Williams, Dean N. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2011-07-20

    This report summarizes work carried out by the Ultra-scale Visualization Climate Data Analysis Tools (UV-CDAT) Team for the period of January 1, 2011 through June 30, 2011. It discusses highlights, overall progress, period goals, and collaborations and lists papers and presentations. To learn more about our project, please visit our UV-CDAT website (URL: http://uv-cdat.org). This report will be forwarded to the program manager for the Department of Energy (DOE) Office of Biological and Environmental Research (BER), national and international collaborators and stakeholders, and to researchers working on a wide range of other climate model, reanalysis, and observation evaluation activities. The UV-CDAT executive committee consists of Dean N. Williams of Lawrence Livermore National Laboratory (LLNL); Dave Bader and Galen Shipman of Oak Ridge National Laboratory (ORNL); Phil Jones and James Ahrens of Los Alamos National Laboratory (LANL), Claudio Silva of Polytechnic Institute of New York University (NYU-Poly); and Berk Geveci of Kitware, Inc. The UV-CDAT team consists of researchers and scientists with diverse domain knowledge whose home institutions also include the National Aeronautics and Space Administration (NASA) and the University of Utah. All work is accomplished under DOE open-source guidelines and in close collaboration with the project's stakeholders, domain researchers, and scientists. Working directly with BER climate science analysis projects, this consortium will develop and deploy data and computational resources useful to a wide variety of stakeholders, including scientists, policymakers, and the general public. Members of this consortium already collaborate with other institutions and universities in researching data discovery, management, visualization, workflow analysis, and provenance. The UV-CDAT team will address the following high-level visualization requirements: (1) Alternative parallel streaming statistics and analysis pipelines - Data

  7. Central airways remodeling in COPD patients

    Directory of Open Access Journals (Sweden)

    Pini L

    2014-09-01

    Full Text Available Laura Pini,1 Valentina Pinelli,2 Denise Modina,1 Michela Bezzi,3 Laura Tiberio,4 Claudio Tantucci1 1Unit of Respiratory Medicine, Department of Clinical and Experimental Sciences, University of Brescia, 2Department of Respiratory Medicine, Spedali Civili di Brescia, 3Department Bronchoscopy, Spedali Civili di Brescia, 4Department of Molecular and Translational Medicine, University of Brescia, Brescia, Italy Background: The contribution to airflow obstruction by the remodeling of the peripheral airways in chronic obstructive pulmonary disease (COPD patients has been well documented, but less is known about the role played by the large airways. Few studies have investigated the presence of histopathological changes due to remodeling in the large airways of COPD patients. Objectives: The aim of this study was to verify the presence of airway remodeling in the central airways of COPD patients, quantifying the airway smooth muscle (ASM area and the extracellular matrix (ECM protein deposition, both in the subepithelial region and in the ASM, and to verify the possible contribution to airflow obstruction by the above mentioned histopathological changes. Methods: Biopsies of segmental bronchi spurs were performed in COPD patients and control smoker subjects and immunostained for collagen type I, versican, decorin, biglycan, and alpha-smooth muscle actin. ECM protein deposition was measured at both subepithelial, and ASM layers. Results: The staining for collagen I and versican was greater in the subepithelial layer of COPD patients than in control subjects. An inverse correlation was found between collagen I in the subepithelial layer and both forced expiratory volume in 1 second and ratio between forced expiratory volume in 1 second and forced vital capacity. A statistically significant increase of the ASM area was observed in the central airways of COPD patients versus controls. Conclusion: These findings indicate that airway remodeling also affects

  8. El espejismo nacional-socialista. La relación entre dos catedráticos de Prehistoria, Oswald Menghin y Julio Martínez Santa-Olalla (1935-1952

    Directory of Open Access Journals (Sweden)

    Mederos Martín, Alfredo

    2014-12-01

    , Claudio Sanchez-Albornoz. Menghin was not permitted to give lectures until 1953, and only consolidated his position when his criminal trial was cancelled in December 1956. In 1957 at the age of 69, he obtained the position of Acting Professor of Prehistory at the National University of La Plata. In 1958, Menghin was appointed Professor in General and Old World Prehistory at the University of Buenos Aires, where he retired in 1968, aged 80.Oswald Menghin, Catedrático de Prehistoria del Hombre de la Universidad de Viena entre 1922-1945, fue partidario de la unidad de Austria con Alemania y simpatizante con ideas del NSDAP sobre la necesidad de evitar una mezcla racial entre arios y judíos. Durante su etapa como Catedrático-Residente en la Universidad de Fouad en El Cairo entre 1930-1933, por contacto con Hermann Junker, radicalizó sus puntos de vista y redactó su libro Espíritu y sangre. Principios básicos de raza, lengua, cultura y nación. Su etapa como Rector en el curso 1935-1936 le catapultó a la política como miembro del consejo directivo del partido fascista austriaco, Vaterländische Front, entre 1936-1937 y su posterior nombramiento como Ministro de Educación entre marzo y mayo de 1938, justo después de la invasión de Hitler de Austria. Siendo Ministro, solicitó su ingreso en el NSDAP, que no se aceptó hasta junio de 1940, por su pertenencia previa a organizaciones católicas secretas. Menghin entró en contacto con Martínez Santa-Olalla, después de la celebración del Jubileo del Instituto de Morfología Cultural de Frankfurt en junio y julio de 1938. A raíz de una estancia de investigación de Almagro Basch en Alemania y Austria en enero y febrero de 1942, y la posterior visita a Barcelona de Menghin en junio de 1942, optó por distanciarse de Martínez Santa-Olalla, no visitando Madrid, cortando la relación epistolar e informando negativamente sobre él a las SS-Ahnenerbe. Prisionero en dos campos de concentración norteamericanos entre mayo de

  9. PREFACE: 5th International Workshop on Top Quark Physics (TOP2012)

    Science.gov (United States)

    Salamanna, G.; Boisvert, V.; Cerrito, L.; Khan, A.; Moretti, S.; Owen, M.; Schwanenberger, C.

    2013-07-01

    resonances in the boosted top regime were also provided. Finally, a set of dedicated talks on the interplay between the top sector and other hot subjects, like the Higgs and SUSY, were given both at the theory and experimental level. Furthermore, ad hoc student sessions were organized to allow younger colleagues to pose questions to the senior experts in the field and contribute with their more recent studies. The conference has been a definitive success, not just scientifically: about 130 participants from all over the world created a collegiate spirit which culminated in the social events at Winchester Hall below King Arthur's table; and in a cosy 16th century barn for the social dinner. The Local Organizing Committee would like to thank all participants, and in particular the speakers, for their high level contributions to TOP 2012 and for making this a very fruitful and pleasant time together. We conclude by wishing the Organizing Committee of TOP 2013 all the best for a successful conference. We look forward to seeing everyone in Germany in 2013. Giuseppe Salamanna Local Organizing Committee London, June 2013 Local Organising Committee Veronique Boisvert (Chair, Royal Holloway, University of London) Lucio Cerrito (Queen Mary, University of London) Akram Khan (Brunel University, London) Stefano Moretti (University of Southampton) Mark Owen (University of Manchester) Giuseppe Salamanna (Queen Mary, University of London) Christian Schwanenberger (University of Manchester) International Advisory Committee Roberto Tenchini (INFN, Pisa) Martine Bosman (IFAE, Barcelona) Michelangelo Mangano (CERN) Scott Willenbrock (University of Illinois, Urbana) Werner Bernreuther (RWTH, Aachen) Jorgen D'Hondt (VUB, Brussels) Antonio Onofre (LIP, University Minho) Fabio Maltoni (UCL, Louvain) Eric Laenen (NIKHEF) Fabrizio Margaroli (INFN, Roma 1) Juan Antonio Aguilar Saavedra (University of Granada) Yvonne Peters (University of Manchester) Roberto Chierici (CERN) Markus Cristinziani

  10. Preface

    Science.gov (United States)

    Andreozzi, Laura; Giordano, Marco; Leporini, Dino; Tosi, Mario

    2003-03-01

    glasses at terahertz frequencies'. The core of the workshop was a set of general lectures followed by more specific presentations on current issues in the main areas of the field. These were covered in sessions devoted sequentially to viscous flow and microscopic relaxation, theoretical aspects, numerical simulation, rheology, glassy materials, confined materials, heterogeneities and energy landscape, polymers, and ageing. Three poster sessions further dealt with the above subjects. The structure of the workshop has been preserved in this publication, in which the set of papers from the plenary lectures is followed by topical contributions in the order in which they were presented. Five contributions to the proceedings come from a selection of the posters. The proceedings end with the round table contributions. We wish here to thank all participants in the workshop, who made it enjoyable and scientifically profitable, and all referees who worked in preparing this special issue of the Journal of Physics: Condensed Matter. We also wish to acknowledge the generous support that we have received from our institutions and the sponsorship and support given by the Istituto Nazionale di Fisica della Materia and by its section Fisica dei Liquidi e Sistemi Disordinati. The Cassa di Risparmio di Pisa hosted the workshop in the splendid location provided by the Convento delle Benedettine. On the behalf of the international scientific community we express our gratitude to all these institutions as well as to those individuals-we mention here in particular Dr Massimo Faetti, Dr Diego Palazzuoli, Dr Fabio Zulli, Ms Beatrice Pistoresi and Ms Patrizia Pucci-who have contributed to organizing and running the workshop.

  11. PREFACE: International Conference "Trends in Spintronics and Nanomagnetism" (TSN-2010)

    Science.gov (United States)

    Maruccio, Giuseppe; Sanvito, Stefano; Hoffmann, Germar; Wiesendanger, Roland; Rowan, Alan

    2011-03-01

    Conference banner The International Conference "Trends in Spintronics and Nanomagnetism" (TSN-2010), was organized by partners of the EU-project SpiDME and held in the historical city of Lecce, Italy from 23-27 May 2010, at the Ecotekne Campus, University of Salento. The conference provided an international forum to discuss recent progress and future trends in the field. In particular, the aim was to bring together the community of more conventional spin-transport, with that of molecular and nano-magnetism. The main topics of TSN-2010 were: MATERIALSSPIN-PHYSICS AND THEORY - Molecular Magnets- Spin injection - Magnetic nanoparticles and nanowires- Domain walls, spin torque and vortex dynamics - Magnetic semiconductors- Numerical modeling of organic nanomagnetism - Multiferroics and transition metal oxides APPLICATIONSADVANCES IN CHARACTERIZATION - Magnetic Multilayers- Magneto-optical characterization and spin manipulation - Spin-photonics- Intrinsic spin transport mechanism in organics - Molecular and nano-spintronics- Organometallic molecules on surfaces - Spin-based quantum computation- Single molecular magnets on surfaces - Magnetism for sensing and nanomedicine- Nanoscale characterization and spin-sensitive SPM The scientific programme started on Monday 24 May and ended on Thursday 27 May. The Nobel Laureate A Fert attended the conference giving a plenary talk and the programme also featured invited presentations by (in alphabetical order): M Aeschlimann, M Affronte, N Atodiresei, P A Bobbert, A Dediu, N Kioussis, L W Molenkamp, J Moodera, V Prigodin, M Ruben, R Sessoli, R Tan, and H Wende. TSN2010 had 150 attendees who came from around the globe to present their latest research in 100 oral presentations. Contributed talks were selected by the program committee, composed of Giuseppe Maruccio, Ross Rinaldi, Valentina Arima, Fabio Della Sala, Maurizio Martino (Universitá del Salento, NNL Institute Nanoscience-CNR, Lecce, Italy), Stefano Sanvito (Trinity College

  12. The association of post-stroke anhedonia with salivary cortisol levels and stroke lesion in hippocampal/parahippocampal region

    Directory of Open Access Journals (Sweden)

    Terroni L

    2015-02-01

    Full Text Available Luisa Terroni,1 Edson Amaro Jr,2 Dan V Iosifescu,3 Patricia Mattos,4 Fabio I Yamamoto,5 Gisela Tinone,5 Adriana B Conforto,5 Matildes FM Sobreiro,1 Valeri D Guajardo,1 Mara Cristina S De Lucia,7 Ayrton C Moreira,6 Milberto Scaff,5 Claudia C Leite,2 Renerio Fraguas1 1Consultation-Liaison Psychiatry Group, Department and Institute of Psychiatry, Clinical Hospital, University of São Paulo School of Medicine, São Paulo, Brazil; 2Department of Radiology, Clinical Hospital, University of São Paulo School of Medicine, São Paulo, Brazil; 3Mood and Anxiety Disorders Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA; 4Department of Psychiatry, Federal University of São Paulo, São Paulo, Brazil; 5Department of Neurology, Clinical Hospital, University of São Paulo School of Medicine, São Paulo, Brazil; 6Department of Medicine, University of São Paulo, School of Medicine, Ribeirão Preto, Brazil; 7Division of Psychology, Central Institute, Clinical Hospital, University of São Paulo School of Medicine, São Paulo, Brazil Background: Anhedonia constitutes a coherent construct, with neural correlates and negative clinical impact, independent of depression. However, little is known about the neural correlates of anhedonia in stroke patients. In this study, we investigated the association of post-stroke anhedonia with salivary cortisol levels and stroke location and volume.Patients and methods: A psychiatrist administered the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition to identify anhedonia in 36 inpatients, without previous depression, consecutively admitted in a neurology clinic in the first month after a first-ever ischemic stroke. Salivary cortisol levels were assessed in the morning, evening, and after a dexamethasone suppression test. We used magnetic resonance imaging and a semi-automated brain morphometry method to assess stroke location, and the MRIcro program

  13. PREFACE: DISCRETE 2012 - Third Symposium on Prospects in the Physics of Discrete Symmetries

    Science.gov (United States)

    Branco, G. C.; Emmanuel-Costa, D.; González Felipe, R.; Joaquim, F. R.; Lavoura, L.; Palomares-Ruiz, S.; Rebelo, M. N.; Romão, J. C.; Silva, J. P.

    2013-07-01

    Romão, J P Silva and J I Silva-Marcos International Advisory CommitteeLocal Organising Committee Francisco del Águila (Granada)From CFTP Jose Bernabéu (Valencia) Francisco Botella (Valencia)G C Branco Andrzej Buras (Munich)D Emmanuel-Costa Marcos Cerrada (Madrid)R González Felipe Pierluigi Campana (CERN)F R Joaquim Antonio Di Domenico (Rome)L Lavoura John Ellis (CERN)S Palomares-Ruiz Fernando Ferroni (Rome)M N Rebelo Luis Garrido (Barcelona)J C Romão Marcello Giorgi (Pisa)J P Silva Neville Harnew (Oxford)J I Silva-Marcos Maria José Herrero (Madrid) David Hitlin (Caltech)From LIP Gino Isidori (Frascati) Guido Martinelli (Rome)G Barreira Antonio Masiero (Padua)J Varela Nickolaos Mavromatos (London) Vasiliki Mitsou (Valencia) Hitoshi Murayama (Berkeley) Tatsuya Nakada (Lausanne) Antonio Pich (Valencia) Apostolos Pilaftsis (Manchester) Stefan Pokorski (Warsaw) Fabio Zwirner (Padua) Secretariat Dulce Conceição Sandra Oliveira Cláudia Romão discrete2012@cftp.ist.utl.pt http://indico.cern.ch/event/discrete2012 Sponsors CFTP - Centro de Física Teórica de Partículas LIP - Laboratório de Instrumentação e Física Experimental de Partículas IST - Instituto Superior Técnico FCT - Fundação para a Ciência e a Tecnologia Group picture The PDF also contains the conference poster and a list of participants.

  14. Testimonies to the L'Aquila earthquake (2009) and to the L'Aquila process

    Science.gov (United States)

    Kalenda, Pavel; Nemec, Vaclav

    2014-05-01

    Lot of confusions, misinformation, false solidarity, efforts to misuse geoethics and other unethical activities in favour of the top Italian seismologists responsible for a bad and superficial evaluation of the situation 6 days prior to the earthquake - that is a general characteristics for the whole period of 5 years separating us from the horrible morning of April 6, 2009 in L'Aquila with 309 human victims. The first author of this presentation as a seismologist had unusual opportunity to visit the unfortunate city in April 2009. He got all "first-hand" information that a real scientifically based prediction did exist already for some shocks in the area on March 29 and 30, 2009. The author of the prediction Gianpaolo Giuliani was obliged to stop any public information diffused by means of internet. A new prediction was known to him on March 31 - in the day when the "Commission of Great Risks" offered a public assurance that any immediate earthquake can be practically excluded. In reality the members of the commission completely ignored such a prediction declaring it as a false alarm of "somebody" (even without using the name of Giuliani). The observations by Giuliani were of high quality from the scientific point of view. G. Giuliani predicted L'Aquila earthquake in the professional way - for the first time during many years of observations. The anomalies, which preceded L'Aquila earthquake were detected on many places in Europe in the same time. The question is, what locality would be signed as potential focal area, if G. Giuliani would know the other observations in Europe. The deformation (and other) anomalies are observable before almost all of global M8 earthquakes. Earthquakes are preceded by deformation and are predictable. The testimony of the second author is based on many unfortunate personal experiences with representatives of the INGV Rome and their supporters from India and even Australia. In July 2010, prosecutor Fabio Picuti charged the Commission

  15. Realistic modeling of seismic input for megacities and large urban areas

    Science.gov (United States)

    Panza, G. F.; Unesco/Iugs/Igcp Project 414 Team

    2003-04-01

    , supply a particularly powerful tool for the prevention aspects of Civil Defense. We present a selection of the main results obtained for the cities of Algiers, Beijing, Bucharest, Cairo, Debrecen, Delhi, Naples, Rome, Russe, Santiago de Cuba, Sofia, Thessaloniki and Zagreb. The UNESCO/IUGS/IGCP PROJECT 414 team members are: Giuliano F. Panza (1,2) (Chairman), Leonardo Alvarez (3), Abdelkrim Aoudia (1,2), Abdelhakim Ayadi (4), Hadj Benhallou (4,5), Djillali Benouar (6), Zoltan Bus (7), Yun-Tai Chen (8), Carmen Cioflan (9), Zhifeng Ding (8), Attia El-Sayed (10), Julio Garcia (3), Bartolomeo Garofalo (11), Alexander Gorshkov (12), Katalin Gribovszki (13), Assia Harbi (4), Panagiotis Hatzidimitriou (14), Marijan Herak (15), Mihaela Kouteva (16), Igor Kuznetzov (12), Ivan Lokmer (15), Said Maouche (4), Gheorghe Marmureanu (9), Margarita Matova (16), Maddalena Natale (11), Concettina Nunziata (11), Imtiyaz Parvez (17,1), Ivanka Paskaleva (16), Ramon Pico (18), Mircea Radulian (9), Fabio Romanelli (2), Alexander Soloviev (12), Peter Suhadolc (2), Gyõzõ Szeidovitz (7), Petros Triantafyllidis (14), Franco Vaccari (2,19). (1) The Abdus Salam International Center for Theoretical Physics, SAND Group, Mirarmar, Trieste, Italy. (2) Department of Earth Sciences, University of Trieste, Via E. Weiss 1, 34127 Trieste, Italy. (3) Centro Nacional de Investigaciones Sismologicas, Cuba. (4) Centre de Recherche en Astronomie, Astrophysique et Geophysique, BP. 63, Bouzaréah, Alger, Algérie. (5) Faculté des Sciences de la Terre de l'Aménagment du Territoire et de la Géographie, USTHB, Alger, Algérie. (6) University of Algiers (USTHB), Civil Engineering Dpt., Alger, Algeria. (7) Hungarian Academy of Sciences, Seismological Observatory of GGRI, H-1112 Budapest, Meredek u. 18, Hungary. (8) Institute of Geophysics, China Seismological Bureau, Beijing, 100081, China. (9) National Institute for Earth Physics, Calugareni 12, P.O.Box: MG 2, 76900 Bucharest-Magurele, Romania. (10) Department of

  16. PREFACE: Strongly Coupled Coulomb Systems Strongly Coupled Coulomb Systems

    Science.gov (United States)

    Neilson, David; Senatore, Gaetano

    2009-05-01

    , condensed matter and ultra-cold plasmas. One hundred and thirty participants came from twenty countries and four continents to participate in the conference. Those giving presentations were asked to contribute to this special issue to make a representative record of an interesting conference. We thank the International Advisory Board and the Programme Committee for their support and suggestions. We thank the Local Organizing Committee (Stefania De Palo, Vittorio Pellegrini, Andrea Perali and Pierbiagio Pieri) for all their efforts. We highlight for special mention the dedication displayed by Andrea Perali, by Rocco di Marco for computer support, and by our tireless conference secretary Fiorella Paino. The knowledgeable guided tour of the historic centre of Camerino given by Fiorella Paino was appreciated by many participants. It is no exaggeration to say that without the extraordinary efforts put in by these three, the conference could not have been the success that it was. For their sustained interest and support we thank Fulvio Esposito, Rector of the University of Camerino, Fabio Beltram, Director of NEST, Scuola Normale Superiore, Pisa, and Daniel Cox, Co-Director of ICAM, University of California at Davis. We thank the Institute of Complex and Adaptive Matter ICAM-I2CAM, USA for providing a video record of the conference on the web (found at http://sccs2008.df.unicam.it/). Finally we thank the conference sponsors for their very generous support: the University of Camerino, the Institute of Complex and Adaptive Matter ICAM-I2CAM, USA, the International Centre for Theoretical Physics ICTP Trieste, and CNR-INFM DEMOCRITOS Modeling Center for Research in Atomistic Simulation, Trieste. Participants at the International Conference on Strongly Coupled Coulomb Systems (SCCS) (University of Camerino, Italy, 29 July-2 August 2008).

  17. Geoethical suggestions for reducing risk of next (not only strong) earthquakes

    Science.gov (United States)

    Nemec, Vaclav

    2013-04-01

    Three relatively recent examples of earthquakes can be used as a background for suggesting geoethical views into any prediction accompanied by a risk analysis. ĹAquila earthquake (Italy - 2009): ĹAquila was largely destroyed by earthquakes in 1315, 1319, 1452, 1461, 1501, 1646, 1703 (until that time altogether about 3000 victims) and 1786 (about 6000 victims of this event only). The city was rebuilt and remained stable until October 2008, when tremors began again. From January 1 through April 5, 2009, additional 304 tremors were reported. When after measuring increased levels of radon emitted from the ground a local citizen (for many years working for the Italian National Institute of Astrophysics) predicted a major earthquake on Italian television, he was accused of being alarmist. Italy's National Commission for Prediction and Prevention of Major Risks met in L'Aquila for one hour on March 31, 2009, without really evaluating and characterising the risks that were present. On April 6 a 6.3 magnitude earthquake struck Aquila and nearby towns, killing 309 people and injuring more than 1,500. The quake also destroyed roughly 20,000 buildings, temporarily displacing another 65,000 people. In July 2010, prosecutor Fabio Picuti charged the Commission members with manslaughter and negligence for failing to warn the public of the impending risk. Many international organizations joined the chorus of criticism wrongly interpreting the accusation and sentence at the first stage as a problem of impossibility to predict earthquakes. - The Eyjafjallajokull volcano eruption (Iceland - 2010) is a reminder that in our globalized, interconnected world because of the increased sensibility of the new technology even a relatively small natural disaster may cause unexpected range of problems. - Earthquake and tsunami (Japan - 2011) - the most powerful known earthquake ever to have hit Japan on March 11. Whereas the proper earthquake with the magnitude of 9.0 has caused minimum of

  18. An innovative intervention for the treatment of cognitive impairment–Emisymmetric bilateral stimulation improves cognitive functions in Alzheimer’s disease and mild cognitive impairment: an open-label study

    Directory of Open Access Journals (Sweden)

    Guerriero F

    2015-09-01

    Full Text Available Fabio Guerriero,1–3 Emanuele Botarelli,3 Gianni Mele,3 Lorenzo Polo,3 Daniele Zoncu,3 Paolo Renati,3,4 Carmelo Sgarlata,1 Marco Rollone,2 Giovanni Ricevuti,1,2 Niccolo Maurizi,1 Matthew Francis,1 Mariangela Rondanelli,5 Simone Perna,5 Davide Guido,2,6 Piero Mannu3 1Department of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, Pavia, Italy; 2Agency for Elderly People Services, Santa Margherita Hospital, Pavia, Italy; 3Ambra Elektron, Italian Association of Biophysics for the Study of Electromagnetic Fields in Medicine, 4Alberto Sorti Research Institute, Medicine and Metamolecular Biology, Turin, Italy; 5Department of Public Health, Experimental and Forensic Medicine, Section of Human Nutrition, Endocrinology and Nutrition Unit, 6Department of Public Health, Experimental and Forensic Medicine, Biostatistics and Clinical Epidemiology Unit, University of Pavia, Pavia, Italy Background and aims: In the last decade, the development of different methods of brain stimulation by electromagnetic fields (EMF provides a promising therapeutic tool for subjects with impaired cognitive functions. Emisymmetric bilateral stimulation (EBS is a novel and innovative EMF brain stimulation, whose working principle is to introduce very weak noise-like stimuli through EMF to trigger self-arrangements in the cortex of treated subjects, thereby improving cognitive faculties. The aim of this pilot study was to investigate in patients with cognitive impairment the effectiveness of EBS treatment with respect to global cognitive function, episodic memory, and executive functions. Methods: Fourteen patients with cognitive decline (six with mild cognitive impairment and eight with Alzheimer’s disease underwent three EBS applications per week to both the cerebral cortex and auricular-specific sites for a total of 5 weeks. At baseline, after 2 weeks and 5 weeks, a neuropsychological assessment was performed through mini–mental state

  19. Combining pain therapy with lifestyle: the role of personalized nutrition and nutritional supplements according to the SIMPAR Feed Your Destiny approach

    Directory of Open Access Journals (Sweden)

    De Gregori M

    2016-12-01

    Full Text Available Manuela De Gregori,1–3 Carolina Muscoli,2,4,5 Michael E Schatman,2,6 Tiziana Stallone,2,7 Fabio Intelligente,2,8 Mariangela Rondanelli,2,9 Francesco Franceschi,2,10 Laura Isabel Arranz,2,11 Silvia Lorente-Cebrián,2,12 Maurizio Salamone,2,13,14 Sara Ilari,2,5 Inna Belfer,2,15 Massimo Allegri2,16,17 1Pain Therapy Service, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy; 2Study in Multidisciplinary Pain Research Group, 3Young Against Pain Group, Parma, Italy; 4Department of Health Sciences, Institute of Research for Food Safety and Health, University “Magna Graecia” of Catanzaro, Parma, Italy; 5IRCCS San Raffaele Pisana, Roccelletta di Borgia, Catanzaro, Italy; 6US Pain Foundation, Bellevue, WA, USA; 7ENPAB, Rome, 8Chronic Pain Service Anestesia Day-Surgery, IRCCS Humanitas Research Hospital, Rozzano, 9Department of Public Health, Section of Human Nutrition and Dietetics, Azienda di Servizi alla Persona di Pavia, University of Pavia, Pavia, 10Institute of Internal Medicine, Catholic University of Rome, Rome, Italy; 11Department of Nutrition, Food Sciences and Gastronomy, University of Barcelona, Barcelona, 12Department of Nutrition, Food Science and Physiology, Center for Nutrition Research, University of Navarra, Pamplona, Spain; 13Metagenics Italia srl, Milano, 14Italian Lifestyle Medicine Association, Bari, Italy; 15Faculty of Dentistry, McGill University, Montreal, QC, Canada; 16Department of Surgical Sciences, University of Parma, 17Anesthesia, Intensive Care and Pain Therapy Service, Azienda Ospedaliero, Universitaria of Parma, Parma, Italy Abstract: Recently, attention to the lifestyle of patients has been rapidly increasing in the field of pain therapy, particularly with regard to the role of nutrition in pain development and its management. In this review, we summarize the latest findings on the role of nutrition and nutraceuticals, microbiome, obesity, soy, omega-3 fatty acids, and curcumin supplementation as key elements in

  20. Increased sugarcane water productivity in Brazil avoids land use change and related environmental impacts

    Science.gov (United States)

    Scarpare, F. V.; Galdos, M. V.; Kolln, O.; Gava, G.; Franco, H.; Trivelin, P.

    2012-12-01

    Fábio V. Scarparea, Marcelo V. Galdosa, Oriel T. Kollna, Glauber J.C. Gavab, Henrique J. Francoa, Paulo C.O. Trivelinc a Laboratório Nacional de Ciência e Tecnologia do Bioetanol - CTBE/CNPEM, C.P. 6170, Campinas, SP, 13083-970, Brazil. E-mail: fabio.scarpare@bioetanol.org.br b APTA - Polo Centro Oeste. Rod. SP 304, km 304, CP 66, Jaú, SP, 17201-970, Brazil. c Laboratório de Isótopos Estáveis, Centro de Energia Nuclear na Agricultura, CENA/USP, C.P. 9, Piracicaba, SP, 13418-900, Brazil. Increasing crop water productivity is a key factor where water is scarce compared with land and other resources. A widespread method for water use assessment is the water productivity (WP) approach which is the ratio between biomass production per unit of water utilized. WP is useful to evaluate water utilization and to identify where and when water can be saved in an irrigation system. Traditionally, field experiments are conducted to quantify and evaluate water management practices in irrigation systems. This field trial was conducted in Jaú - São Paulo State (Lat 22.17° S, Long 48.32° W) during first and second ratoon cycles. Four treatments were appraised; rainfed only (R0); rainfed + 150 kg ha-1 of N (RN); irrigation only (I0) and irrigation + 150 kg ha-1 of N (IN). The subsurface drip irrigation was carried out considering the crop evapotranspiration (ETc) to restore 100% of evapotranspired water. The irrigation frequency was considered the water supply to the soil by precipitation and the atmospheric demand for sugarcane ETc, with a maximum soil storage capacity of 70 mm. Our results point that the WP in irrigated condition was 13% higher than rainfed field whereas for N application, WP reached even higher values, 40%. WP among all treatments showed better results for IN (~28 kg mm-1) followed by RN (~23 kg mm-1); I0 (~16 kg mm-1) and R0 (~15 kg mm-1). Those results are in agreement with some studies which suggest high synergy between water and nitrogen for the

  1. A case study of ethanol water demand during industrial phase in Brazil

    Science.gov (United States)

    Hernandes, T.; Scarpare, F. V.; Guarenghi, M.; Pereira, T.; Galdos, M. V.

    2012-12-01

    Thayse A. D. Hernandesb, Fábio V. Scarparea, Marjorie M. Guarenghib, Tássia P. Pereirab, Marcelo V. Galdosa a Laboratório Nacional de Ciência e Tecnologia do Bioetanol - CTBE/CNPEM, Caixa Postal 6170, 13083-970 Campinas, São Paulo, Brazil, E-mail: fabio.scarpare@bioetanol.org.br b Faculdade de Engenharia Mecânica, Unicamp, Cidade Universitária "Zeferino Vaz", CEP 13083-860, Campinas, SP, Brazil In São Paulo State, the water resources have being used by sugarcane industry responsibly, through high reuse rates that may reach 95% during industrial process. The average amount of catchment water stays around 2.0 m3 Mg 1 of industrial sugarcane stalk. However, in some modern mills which use higher technical level of closed water circuit, the standard goal for sugarcane industry, 1.0 m3 Mg 1 can be reached. In some regions where the uptake water for industrial segment is high as in São Paulo State, water use assessment is desired for sustainable ethanol production. Thus, two regions in São Paulo State with two plants each were taken as a case study aiming to assess ethanol water demand during the industrial phase. Araraquara was the first study region where the water demand was classified as in critical condition in 2010 according to the Water and Electrical Energy Department of São Paulo State (DAEE). The industrial activities were responsible for 50% of the water catchment. Araçatuba was the second study region where water demand was classified as being of concern (DAEE) due to high percentage of catchment water for industrial activities, around 90%. Data regarding the amount of millable cane processed, days of the plant operation, ratio of cane used for ethanol production in 2010/2011 season were used for direct water demand estimation considering different water catchment scenarios of 2.0, 1.0 and 0.7 (technological development prediction scenario) m3 Mg-1 of millable cane. For indirect water demand estimation, data regarding installed capacity of each

  2. Radiological response and survival in locally advanced non-small-cell lung cancer patients treated with three-drug induction chemotherapy followed by radical local treatment

    Directory of Open Access Journals (Sweden)

    Bonanno L

    2016-06-01

    Full Text Available Laura Bonanno,1 Giulia Zago,1 Giuseppe Marulli,2 Paola Del Bianco,3 Marco Schiavon,2 Giulia Pasello,1 Valentina Polo,1,4 Fabio Canova,1 Fabrizio Tonetto,5 Lucio Loreggian,5 Federico Rea,2 PierFranco Conte,1,4 Adolfo Favaretto1 1Medical Oncology Unit 2, Veneto Institute of Oncology IOV-IRCCS, 2Thoracic Surgery Department, University of Padova, 3Clinical Trials and Biostatistics Unit, Veneto Institute of Oncology IOV-IRCCS, 4Department of Surgery, Oncology and Gastroenterology, University of Padova, 5Radiotherapy Unit, Veneto Institute of Oncology IOV-IRCCS, Padova, Italy Objectives: If concurrent chemoradiotherapy cannot be performed, induction chemotherapy followed by radical-intent surgical treatment is an acceptable option for non primarily resectable non-small-cell lung cancers (NSCLCs. No markers are available to predict which patients may benefit from local treatment after induction. This exploratory study aims to assess the feasibility and the activity of multimodality treatment, including triple-agent chemotherapy followed by radical surgery and/or radiotherapy in locally advanced NSCLCs. Methods: We retrospectively collected data from locally advanced NSCLCs treated with induction chemotherapy with carboplatin (area under the curve 6, d [day]1, paclitaxel (200 mg/m2, d1, and gemcitabine (1,000 mg/m2 d1, 8 for three to four courses, followed by radical surgery and/or radiotherapy. We analyzed radiological response and toxicity. Estimated progression-free survival (PFS and overall survival (OS were correlated to response, surgery, and clinical features. Results: In all, 58 NSCLCs were included in the study: 40 staged as IIIA, 18 as IIIB (according to TNM Classification of Malignant Tumors–7th edition staging system. A total of 36 (62% patients achieved partial response (PR, and six (10% progressions were recorded. Grade 3–4 hematological toxicity was observed in 36 (62% cases. After chemotherapy, 37 (64% patients underwent surgery

  3. trash epoch

    Directory of Open Access Journals (Sweden)

    Elena Grigoryeva

    2012-02-01

    . Japan processes 96% of waste, Germany 95%, Poland 16%, Russia only 5%. At this moment the territory of Russia has accumulated 100 billion tons of garbage – there is scarcely any deposit of such a large scale. Waste recycling plants are a vital task for today’s and tomorrow’s architecture (102–105.The architecture itself is no longer designed for centuries. The green standards contain such an essential item as engineering redesign for dismantled or demolished structures. Instead of the philosophical principle “my house is my fortress”, the impermanence is on the agenda today. A house, like a short-life packing or tomorrow’s garbage, is now under the statement of the problem.This issue returns to its regular sections. In the HERITAGE section there is an article by our American contributor Brian Spencer (124–129; and a debut of Fabio Todeschini, Professor from South Africa (130–136. In the LANDSCAPE section we start publishing a series of articles by Olga Smirnova (142–147, a Krasnoyarsk architect, poet and traveler…

  4. Efficacy of trabectedin in advanced soft tissue sarcoma: beyond lipo- and leiomyosarcoma

    Directory of Open Access Journals (Sweden)

    De Sanctis R

    2015-10-01

    Full Text Available Rita De Sanctis,1 Andrea Marrari,1 Silvia Marchetti,1 Chiara Mussi,2 Luca Balzarini,3 Fabio Romano Lutman,3 Primo Daolio,4 Stefano Bastoni,4 Alexia Francesca Bertuzzi,1,5 Vittorio Quagliuolo,2 Armando Santoro1 1Department of Medical Oncology and Haematology, 2Department of Surgical Oncology, 3Department of Radiology, Humanitas Cancer Center, IRCCS, Rozzano, 4Department of Surgical Oncology, Orthopaedic Institute “G. Pini”, Milan, Italy; 5Department of Medical Oncology, Adelaide and Meath Hospital, Incorporating the National Children’s Hospital (AMNCH, Dublin, Ireland Objective: Trabectedin is effective in leiomyosarcoma and liposarcoma, especially the myxoid variant, related to the presence of the FUS-CHOP transcript. We evaluated the efficacy of trabectedin in specific subgroups of patients with soft tissue sarcomas (STS.Methods: Seventy-two patients with advanced anthracycline-pretreated STS, who received trabectedin at a dose of 1.5 mg/m2 every 3 weeks by continuous 24-hour infusion, were retrospectively analyzed. Best response rate according to Response Evaluation Criteria In Solid Tumors (RECIST criteria and severe adverse events (AEs according to National Cancer Institute Common Terminology Criteria for Adverse Events (NCI-CTCAE v4.02 were evaluated. Secondary endpoints included progression-free survival and overall survival (OS.Results: Median age was 48 (range, 20–75 years, with a median Eastern Cooperative Oncology Group performance status of 0. The median number of previous chemotherapy regimens was 1 (range, 0–5. Median number of trabectedin cycles was 3 (range, 1–17. About 69/72 patients (95.8% were evaluable for response: 9 patients (13% achieved partial response and 26 (37.7% stable disease. According to histotype, clinical benefit (partial response + stable disease was reported in synovial sarcoma (n=5, retroperitoneal liposarcoma (n=10, myxoid liposarcoma (n=5, leiomyosarcoma (n=8, high-grade undifferentiated

  5. 3d-modelling workflows for trans-nationally shared geological models - first approaches from the project GeoMol

    Science.gov (United States)

    Rupf, Isabel

    2013-04-01

    framework model are interpreted seismic lines, 3d-models can be generated either in time or in depth domain. Some partners will build their 3d-model in time domain and convert it after finishing to depth. Other participants will transform seismic information first and will model directly in depth domain. To ensure comparability between the different parts transnational velocity models for time-depth conversion are required at an early stage of the project. The exchange of model geometries, topology, and geo-scientific content will be achieved applying an appropriate cyberinfrastructure called GST. It provides functionalities to ensure semantic and technical interoperability. Within the project GeoMol a web server for the dissemination of 3d geological models will be implemented including an administrative interface for the role-based access, real-time transformation of country-specific coordinate systems and a web visualisation features. The project GeoMol is co-funded by the Alpine Space Program as part of the European Territorial Cooperation 2007-2013. The project integrates partners from Austria, France, Germany, Italy, Slovenia and Switzerland and runs from September 2012 to June 2015. Further information on www.geomol.eu. The GeoMol 3D-modelling team: Roland Baumberger (swisstopo), Magdalena Bottig (GBA), Alessandro Cagnoni (RLB), Laure Capar (BRGM), Renaud Couëffé (BRGM), Chiara D'Ambrogi (ISPRA), Chrystel Dezayes (BRGM), Gerold Diepolder (LfU BY), Charlotte Fehn (LGRB), Sunseare Gabalda (BRGM), Gregor Götzl (GBA), Andrej Lapanje (GeoZS), Fabio Carlo Molinari (RER-SGSS), Edgar Nitsch (LGRB), Robert Pamer (LfU BY), Sebastian Pfleiderer (GBA), Marco Pantaloni (ISPRA), Uta Schulz (LfU BY), Günter Sokol (LGRB), Gunther Wirsing (LGRB), Heiko Zumsprekel (LGRB)

  6. Effects of aliskiren- and ramipril-based treatment on central aortic blood pressure in elderly with systolic hypertension: a substudy of AGELESS

    Directory of Open Access Journals (Sweden)

    Baschiera F

    2014-06-01

    Full Text Available Fabio Baschiera,1 William Chang,2 Patrick Brunel1 On behalf of the AGELESS Study Group 1Novartis Pharma AG, Basel, Switzerland; 2Novartis Pharmaceuticals Corporation, East Hanover, NJ, USA Background: Systolic hypertension is the most common form of hypertension in elderly patients. There is increasing evidence that measurement of central aortic pressure (CAP better accounts for cardiovascular risk than brachial blood pressure (BP. The Aliskiren for GEriatric LowEring of SyStolic hypertension (AGELESS study in elderly patients with systolic hypertension showed that aliskiren-based therapy provided greater reductions in peripheral BP than ramipril-based therapy over 12 and 36 weeks of treatment. Here, we present CAP results in a substudy of elderly patients from the AGELESS study. Methods: This was a post hoc analysis of a 36-week, randomized, double-blind, parallel-group, active-controlled, optional-titration study in patients ≥65 years of age with systolic BP ≥140 mmHg. Changes in both central and peripheral BP and pulse pressure (PP and changes in systolic and PP amplification ratios from baseline to the week 36 end point with aliskiren-based versus ramipril-based therapy were analyzed. Results: Of the 901 patients randomized in the overall study, 154 patients (aliskiren, n=78; ramipril, n=76 had CAP data. Numerically comparable reductions were seen for central aortic systolic pressure (CASP in aliskiren-based therapy (baseline: 143.7±15.0; week 36: −20.3±16.2 compared with ramipril-based therapy (baseline: 147.9±11.9; week 36: −20.7±14.6. However, for the change in central aortic diastolic pressure, the least squares mean between-treatment difference (−3.6 mmHg [95% confidence interval, −6.76, −0.43; P=0.0263] was in favor of aliskiren, while the other changes were comparable between the two groups with a trend in favor of aliskiren for CASP as well (−2.6 mmHg [95% confidence interval, −7.38, 2.19; P=0

  7. Mesenchymal stromal cell labeling by new uncoated superparamagnetic maghemite nanoparticles in comparison with commercial Resovist – an initial in vitro study

    Directory of Open Access Journals (Sweden)

    Skopalik J

    2014-11-01

    Full Text Available Josef Skopalik,1 Katerina Polakova,2 Marketa Havrdova,2 Ivan Justan,1 Massimiliano Magro,3 David Milde,2 Lucia Knopfova,4 Jan Smarda,4 Helena Polakova,1 Eva Gabrielova,5 Fabio Vianello,2,3 Jaroslav Michalek,1 Radek Zboril21Department of Pharmacology, Masaryk University, Brno, Czech Republic; 2Regional Centre of Advanced Technologies and Materials, Department of Physical Chemistry and Analytical Chemistry, Faculty of Science, Palacky University, Olomouc, Czech Republic; 3Department of Comparative Biomedicine and Food Science, University of Padua, Padova, Italy; 4Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic; 5Department of Medical Chemistry and Biochemistry, Faculty of Medicine, Palacky University, Olomouc, Czech RepublicObjective: Cell therapies have emerged as a promising approach in medicine. The basis of each therapy is the injection of 1–100×106 cells with regenerative potential into some part of the body. Mesenchymal stromal cells (MSCs are the most used cell type in the cell therapy nowadays, but no gold standard for the labeling of the MSCs for magnetic resonance imaging (MRI is available yet. This work evaluates our newly synthesized uncoated superparamagnetic maghemite nanoparticles (surface-active maghemite nanoparticles – SAMNs as an MRI contrast intracellular probe usable in a clinical 1.5 T MRI system.Methods: MSCs from rat and human donors were isolated, and then incubated at different concentrations (10–200 µg/mL of SAMN maghemite nanoparticles for 48 hours. Viability, proliferation, and nanoparticle uptake efficiency were tested (using fluorescence microscopy, xCELLigence analysis, atomic absorption spectroscopy, and advanced microscopy techniques. Migration capacity, cluster of differentiation markers, effect of nanoparticles on long-term viability, contrast properties in MRI, and cocultivation of labeled cells with myocytes were also studied.Results: SAMNs do not

  8. The nasal delivery of nanoencapsulated statins – an approach for brain delivery

    Directory of Open Access Journals (Sweden)

    Clementino A

    2016-12-01

    Full Text Available Adryana Clementino,1,2 Mellissa Batger,3 Gabriela Garrastazu,2,3 Michele Pozzoli,3 Elena Del Favero,4 Valeria Rondelli,4 Bianca Gutfilen,5 Thiago Barboza,5 Maria B Sukkar,3 Sergio A L Souza,5 Laura Cantù,4 Fabio Sonvico1,3 1Department of Pharmacy, University of Parma, Parma, Italy; 2National Council for Scientific and Technological Development – CNPq, Brasilia, Brazil; 3Graduate School of Health – Pharmacy, University of Technology Sydney, Ultimo, NSW, Australia; 4Department of Medical Biotechnologies and Translational Medicine, LITA, University of Milan, Segrate, Italy; 5Laboratório de Marcação de Células e Moléculas, Department of Radiology, Faculty of Medicine, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil Purpose: Along with their cholesterol-lowering effect, statins have shown a wide range of pleiotropic effects potentially beneficial to neurodegenerative diseases. However, such effects are extremely elusive via the conventional oral administration. The purpose of the present study was to prepare and characterize the physicochemical properties and the in vivo biodistribution of simvastatin-loaded lecithin/chitosan nanoparticles (SVT-LCNs suitable for nasal administration in view of an improved delivery of the statins to the brain. Materials and methods: Chitosan, lecithin, and different oil excipients were used to prepare nanocapsules loaded with simvastatin. Particle size distribution, surface charge, structure, simvastatin loading and release, and interaction with mucus of nanoparticles were determined. The nanoparticle nasal toxicity was evaluated in vitro using RPMI 2651 nasal cell lines. Finally, in vivo biodistribution was assessed by gamma scintigraphy via Tc99m labeling of the particles. Results: Among the different types of nanoparticles produced, the SVT-LCN_MaiLab showed the most ideal physicochemical characteristics, with small diameter (200 nm, positive surface charge (+48 mV and high encapsulation

  9. Precios y oferta para el culantro castilla (Coriandrum sativum L. entre los principales mercados mayoristas de Costa Rica y Panama

    Directory of Open Access Journals (Sweden)

    Alexis Villalobos Monge

    2012-05-01

    Full Text Available Este artículo muestra los resultados del análisis compa- rativo de precios y volúmenes ofertados del culantro de castilla en los principales mercados mayoristas de Costa Rica y Panamá. Como antecedente se tiene la ejecución de una gira de prospección realizada en el 2009 a Ciudad de Panamá por parte de los colaboradores del proyecto “Investigación de mercados agrícolas” de la Estación Ex- perimental Fabio Baudrit de la Universidad de Costa Rica. En esta gira se detectó que el culantro castilla presentaba interesantes oportunidades de mercado gracias al precio y a la calidad del producto ofertado, razón por la cual se definió, como línea de trabajo, profundizar en aspectos de esta índole para determinar las particularidades de los principales mercados mayoristas de cada país en el caso de este alimento. Se llevó a cabo una revisión de series de tiempo para datos de precio y oferta emitidos por las fuentes encargadas de cada mercado, con los que se reali- zaron comparaciones de estadísticos y análisis de tenden- cia por regresión lineal, los cuales permitieron dimensionar las diferencias entre ambos sitios para enmarcar el com- portamiento del culantro castilla como potencial agrone- gocio, relacionado con el consumo a nivel de cada país. Entre los principales hallazgos, se puede mencionar que en Costa Rica históricamente ha existido un mayor con- sumo de esta hortaliza en comparación con Panamá, sin embargo, la tendencia detectada en Panamá, en cuanto a precios y volúmenes ofertados, está creciendo a mayor velocidad en este último mercado. Las diferencias prome- dio de precios pagados en Panamá superan por más del 100% a los pagados en Costa Rica por la misma unidad de comercialización según series mensuales para un periodo de 4 años, razón por la que se afinó la observación y se analizaron las plazas de comercialización para un total de 246 plazas mayoristas, donde se encontró que en el 94% de las veces

  10. Long-term efficacy and safety of oxycodone–naloxone prolonged release in geriatric patients with moderate-to-severe chronic noncancer pain: a 52-week open-label extension phase study

    Directory of Open Access Journals (Sweden)

    Guerriero F

    2016-04-01

    Full Text Available Fabio Guerriero,1,2 Anna Roberto,3 Maria Teresa Greco,4 Carmelo Sgarlata,1 Marco Rollone,2 Oscar Corli3 1Department of Internal Medicine and Medical Therapy, Section of Geriatrics, University of Pavia, 2Department of Geriatrics, Agency for Elderly People of Pavia, Santa Margherita Institute, Pavia, 3Department of Oncology, Pain and Palliative Care Research Unit, IRCCS-Mario Negri Institute for Pharmacological Research, 4Unit of Medical Statistics, Biometry and Epidemiology GA Maccacaro, Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy Background: Two-thirds of older people suffer from chronic pain and finding valid treatment options is essential. In this 1-yearlong investigation, we evaluated the efficacy and safety of prolonged-release oxycodone–naloxone (OXN-PR in patients aged ≥70 (mean 81.7 years.Methods: In this open-label prospective study, patients with moderate-to-severe noncancer chronic pain were prescribed OXN-PR for 1 year. The primary endpoint was the proportion of patients who achieved ≥30% reduction in pain intensity after 52 weeks of treatment, without worsening bowel function. The scheduled visits were at baseline (T0, after 4 weeks (T4, and after 52 weeks (T52.Results: Fifty patients completed the study. The primary endpoint was achieved in 78% of patients at T4 and 96% at T52 (P<0.0001. Pain intensity, measured on a 0–10 numerical rating scale, decreased from 6.0 at T0 to 2.8 at T4 and to 1.7 at T52 (P<0.0001. Mean daily dose of oxycodone increased from 10 to 14.4 mg (T4 and finally to 17.4 mg (T52. Bowel Function Index from 35.1 to 28.7 at T52. No changes were observed in cognitive functions (Mini-Mental State Examination evaluation, while daily functioning improved (Barthel Index from 53.1 to 61.0, P<0.0001. The Screener and Opioid Assessment for Patients with Pain-Revised score at 52 weeks was 2.6 (standard deviation 1.6, indicating a low risk of aberrant medication

  11. Pulmonary embolism in the elderly: a review on clinical, instrumental and laboratory presentation

    Directory of Open Access Journals (Sweden)

    Luca Masotti

    2008-06-01

    Full Text Available Luca Masotti1,8, Patrick Ray2, Marc Righini3, Gregoire Le Gal4, Fabio Antonelli5, Giancarlo Landini1, Roberto Cappelli6, Domenico Prisco7, Paola Rottoli81Internal Medicine, Cecina Hospital, Cecina, Italy; 2Department of Emergency Medicine, Centre Hospitalo-Universitaire Pitié-Salpêtrière, Université Pierre et Marie Curie-Paris 6, Paris, France; 3Division of Angiology and Hemostasis, Geneva University Hospital and Faculty of Medicine, Geneva, Switzerland; 4Department of Internal Medicine and Chest Diseases, Brest University Hospital, Brest, France; 5Clinical Chemistry, Cecina Hospital, Cecina, Italy; 6Department of Internal, Cardiovascular and Geriatric Medicine, University of Siena, Siena, Italy; 7Department of Critical Care Medicine, Thrombosis Centre, Careggi Hospital, Florence, Italy; 8Departiment of Clinical Medicine and Immunological Sciences, Division of Respiratory Diseases, University of Siena, Siena, ItalyObjective: Diagnosis of pulmonary embolism (PE remains difficult and is often missed in the elderly due to nonspecific and atypical presentation. Diagnostic algorithms able to rule out PE and validated in young adult patients may have reduced applicability in elderly patients, which increases the number of diagnostic tools use and costs. The aim of the present study was to analyze the reported clinical presentation of PE in patients aged 65 and more.Materials and Methods: Prospective and retrospective English language studies dealing with the clinical, instrumental and laboratory aspects of PE in patients more than 65 and published after January 1987 and indexed in MEDLINE using keywords as pulmonary embolism, elderly, old, venous thromboembolism (VTE in the title, abstract or text, were reviewed.Results: Dyspnea (range 59%–91.5%, tachypnea (46%–74%, tachycardia (29%–76%, and chest pain (26%–57% represented the most common clinical symptoms and signs. Bed rest was the most frequent risk factor for VTE (15%–67%; deep vein

  12. The Serra de Tramuntana World Heritage Site (Mallorca, Spain). Landslide activity valuation by means of Persistent Scatterers Interferometry

    Science.gov (United States)

    Mateos, Rosa Maria; Bianchini, Silvia; Herrera, Gerardo; Garcia, Inmaculada; Sanabria, Margarita

    2016-04-01

    cultural heritage sites. References: Bianchini S, Herrera G, Mateos RM, Notti D, García-Moreno I, Mora O, Moretti S (2013). Landslide Activity Maps Generation by means of Persistent Scattered Interferometry. Remote Sensing 5:6198-6222. Mateos R.M., García-Moreno I., Herrera G., Mulas J (2013) a. Damage caused by recent mass-movements in Majorca (Spain), a region with a high risk due to tourism. Landslide Science and Practice. Claudio Margottini, Paolo Canuti and Kyoji Sassa (Editors). Volume 7: Social and Economic Impact and Policies. 105-113. Mateos RM, Rodríguez-Peces M, Azañón JM, Rodríguez-Fernández FJ, Roldán FJ, García-Moreno I, Gelabert B, García-Mayordomo J (2013)b. El deslizamiento de Bàlitx (Mallorca) y su posible origen sísmico. Procesos activos desde el Pleistoceno superior. Boletín Geológico y Minero, 124 (1): 41-61

  13. El foro romano de Termes (Hispania Citerior. Síntesis histórica, arqueológica y topográfica. S. I a. C.- s. II d. C.

    Directory of Open Access Journals (Sweden)

    Martínez Caballero, Santiago

    2010-12-01

    progresiva superposición de estructuras en la zona. Durante la etapa Julio Claudia (14-37 d. C. se creó una nueva área pública, junto a la anterior, conformada por un recinto porticado con un templo. Este conjunto formaba parte de un espacio público principal, bien un Foro Julio Claudio, bien simplemente un santuario urbano. Finalmente, en época flavia, a partir de 75 d. C., el sitio del foro augusteo será transformado con la construcción de un gran cuadripórtico monumental y escenográfico, el Foro Flavio, complejo que se constituirá, al mismo tiempo, como un foro y un Augusteum, espacio de representación y santuario de culto dinástico.

  14. Variability of DTM-derived, morphometric parameters versus cell size. An example of application in Calabria (Southern Italy)

    Science.gov (United States)

    Rago, Valeria; Caloiero, Paola; Pellegrino, Annamaria Daniela; Iovine, Giulio G. R.; Terranova, Oreste G.; Pascale, Stefania

    2016-04-01

    , G. Gullà, G. Iovine, O. Petrucci, P. Salvador Sanchis, M. Sorriso-Valvo, O. Terranova, D. Torri, V. Bagarello, C. Di Stefano, V. Ferro, G. Buttafuoco, G. Callegari, P. Porto, B. Betrò, A. Bodini, C. Brambilla (2010) - Relazione Finale Contratto Lotto 2 Pericolosità legata ai fenomeni di intensa erosione idrica areale e lineare- POR Calabria 2000-2006, Azione. 1.4c. Rapporto per Autorità di Bacino Regione Calabria. Iovine G., Greco R., Gariano S.L., Pellegrino A.D., Terranova O.G. (2014) - Shallow-landslide susceptibility in the Costa Viola mountain ridge (southern Calabria, Italy) with considerations on the role of causal factors. Natural Hazards, 73(1), pp.111-136. In: G. Iovine & D. Cohen (Eds.), Advanced methods in landslide modelling. Iovine G., Greco R., Gariano S.L., Iaquinta P., Pellegrino A.D., Terranova O.G. (2013) - Shallow-landslide susceptibility in the Costa Viola mountain ridge (Italia). In: Landslide Science and Practice, Claudio Margottini, Paolo Canuti, Kyoji Sassa (Editors), Volume 3: Spatial Analysis and Modelling, pp.81-87. Proc. Second World Landslide Forum, 3-7 October 2011, Rome.

  15. Seasonal rockfall risk assessment along transportation network: a sample from Mallorca (Spain)

    Science.gov (United States)

    Mateos, Rosa Maria; Garcia, Inmaculada; Reichenbach, Paola; Herrera, Gerardo; Rius, Joan; Aguilo, Raul; Roldan, Francisco J.

    2014-05-01

    section of the road. For the risk analysis, four scenarios depending on the seasonal people exposition have been taken into account, considering the autumn as the season with the highest risk. This methodology can be applied to highly touristy areas such Mallorca, where the safety of the population and its visitors must be the priority of all concerned. References : Guzzetti, F., Crosta G., Detti, R. Agliardi, F., 2002: STONE: A computer program for the three-dimensional simulation of rock-falls. Computers Geosciences 28 (2002) 1079-1093. Mateos, R.M., García-Moreno, I., Azañón, J.M., 2012. Freeze-thaw cycles and rainfall as triggering factors of mass movements in a warm Mediterranean region: the case of the Tramuntana Range (Majorca, Spain). Landslides (2012), 9: 417-432. Mateos, R.M., García- Moreno, I., Herrera, G., Mulas, J., 2013b. Damage caused by recent mass-movements in Majorca (Spain), a region with a high risk due to tourism. Landslide Science and Practice. Claudio Margottini, Paolo Canuti and Kyoji Sassa (Editors). Volume 7: Social and Economic Impact and Policies. 105-113.

  16. Budget impact analysis of sofosbuvir-based regimens for the treatment of HIV/HCV-coinfected patients in northern Italy: a multicenter regional simulation

    Directory of Open Access Journals (Sweden)

    Cenderello G

    2015-12-01

    Full Text Available Giovanni Cenderello,1 Stefania Artioli,2 Claudio Viscoli,3 Ambra Pasa,4 Mauro Giacomini,5 Barbara Giannini,5 Chiara Dentone,6 Laura Ambra Nicolini,3 Giovanni Cassola,1 Antonio Di Biagio31Infectious Diseases Unit EO, Ospedali Galliera, Genoa, 2Infectious Diseases Unit, ASL-5 Spezzina, La Spezia, 3Infectious Diseases Unit, AOU San Martino, IST, Genoa University, Genoa, 4IT Unit, Ospedali Galliera, Genoa, 5Department of Informatics, Bioengineering, Robotics and System Engineering (DIBRIS, University of Genoa, Genova, 6Infectious Diseases Unit, ASL-1 Imperiese, Sanremo, Imperia, ItalyObjectives: Chronic hepatitis C virus (HCV is a leading cause of hospitalization and death in populations coinfected with human immunodeficiency virus (HIV. Sofosbuvir (SOF is a pan-genotypic drug that should be combined with other agents as an oral treatment for HCV. We performed a 5-year horizon budget impact analysis of SOF-based regimens for the management of HIV/HCV-coinfected patients.Methods: A multicenter, prospective evaluation was conducted, involving four Italian Infectious Diseases Departments (Galliera, San Martino, Sanremo, and La Spezia. All 1,005 genotype-coinfected patients (30% cirrhotics under observation were considered (patients in all disease-stages were considered: chronic hepatitis C, cirrhosis, transplant, hepatocellular carcinoma. Disease stage costs per patient were collected; the expected disease progression in the absence of treatment and sustained virological response (SVR success rate for SOF-based regimens were calculated based on the literature and expert opinion. Drug prices were based on what the National Health Service paid for them. The comparison of "no treatment" disease progression costs versus the economic impact of SOF-based regimens was investigated.Results: Over the following 5 years, the disease progression scenario resulted in direct costs of approximately €54 million. Assuming an SVR success rate of 90%, average SOF

  17. Analysis of cardiac autonomic modulation of children with attention deficit hyperactivity disorder

    Directory of Open Access Journals (Sweden)

    de Carvalho TD

    2014-04-01

    Full Text Available Tatiana Dias de Carvalho,1,2 Rubens Wajnsztejn,3 Luiz Carlos de Abreu,2,7 Luiz Carlos Marques Vanderlei,4 Moacir Fernandes Godoy,5 Fernando Adami,2 Vitor E Valenti,6 Carlos B M Monteiro,2,7 Claudio Leone,7 Karen Cristina da Cruz Martins,2 Celso Ferreira11Departamento de Medicina, Disciplina de Cardiologia, Universidade Federal de São Paulo, UNIFESP, São Paulo, Brazil; 2Laboratório de Escrita Científica da Faculdade de Medicina do ABC, FMABC, Santo André, Brazil; 3Núcleo Especializado em Aprendizagem, Programa de pós-graduação em Ciências da Saúde da Faculdade de Medicina do ABC, FMABC, Santo André, Brazil; 4Departamento de Fisioterapia da Faculdade de Ciências e Tecnologia, Universidade Estadual Paulista, UNESP, Presidente Prudente, São Paulo, Brazil; 5Núcleo Transdisciplinar de Estudos do Caos e da Complexidade. Faculdade de Medicina de São José de Rio Preto, FAMERP, São José do Rio Preto, Brazil; 6Departamento de Fonoaudiologia da Faculdade de Filosofia e Ciências, Universidade Estadual Paulista, UNESP, Marília, Brazil; 7Departamento de Saúde Materno-Infantil da Faculdade de Saúde Pública da Universidade de São Paulo, São Paulo, BrazilBackground: Attention deficit hyperactivity disorder (ADHD is characterized by decreased attention span, impulsiveness, and hyperactivity. Autonomic nervous system imbalance was previously described in this population. We aim to compare the autonomic function of children with ADHD and controls by analyzing heart rate variability (HRV.Methods: Children rested in supine position with spontaneous breathing for 20 minutes. Heart rate was recorded beat by beat. HRV analysis was performed in the time and frequency domains and Poincaré plot.Results: Twenty-eight children with ADHD (22 boys, aged 9.964 years and 28 controls (15 boys, age 9.857 years participated in this study. It was determined that the mean and standard deviation of indexes which indicate parasympathetic activity is higher in

  18. PREFACE: EPS Euroconference XIX Nuclear Physics Divisional Conference: New Trends in Nuclear Physics Applications and Technology

    Science.gov (United States)

    2006-06-01

    . Role of Nuclear Techniques in Environment Problems. Applications of Nuclear Techniques relevant for Civil Security (contraband and explosive detection, search for Weapons of Mass Destruction, Nuclear Safeguards). Nuclear Applications in Space Research. Material and Structure Testing in Research and Industry. New contributions of Nuclear Techniques to the solution of the Energy Production problems and Nuclear Waste Transmutation. Emerging experimental techniques, new detectors and new modeling tools. During the Monday morning Session of the Conference, the 2005 IBA-EUROPHYSICS PRIZE for Applied Nuclear Science and Nuclear Methods in Medicine, sponsored by the Belgian company IBA, was awarded to the two laureates Werner Heil (Mainz) and Pierre Jean Nacher (Paris) for the development of spin polarized 3He targets by optical pumping and their applications in nuclear science and medicine. The meeting was a real success, with 18 invited talks, 66 contributed talks and 31 posters and an overall participation, during five full days, of around 150 scientists from different European and non-European countries. It also hosted a three day industrial exhibition of a selection of Companies that sponsored the event. The Organisers take thos opportunity to thank the University of Pavia, the Amministrazione Comunale di Pavia and the Provincia di Pavia, as well as all exhibitors (Ametek, Ansaldo Superconduttori, Caen, Else, Hamamatsu, IBA, Micos, Micron Semiconductor), for their support of the Conference. The Organisers finally wish to thank the Scientific Secretary of the Conference, Dr Andrea Fontana of INFN Pavia, for the huge amount of work done in preparing the Conference, Mr Claudio Casella of the Department of Nuclear and Theoretical Physics of the University of Pavia for technical support and the Conference staff, Dr Gaia Boghen and the graduate students Federica Devecchi and Silvia Franchino, for their invaluable help. The very effective and professional work of the staff of

  19. Editorial v. 4, n. 3

    Directory of Open Access Journals (Sweden)

    Júlio Araujo Carneiro da Cunha

    2016-01-01

    Full Text Available O ano de 2015 foi marcado por avanços e mudanças na PODIUM Sport, Leisure and Tourism Review. Numa retrospectiva dos indicadores da revista ao longo do ano, tivemos 23 artigos publicados em três edições. Houve 67 autores que representaram 21 instituições de ensino do país, além de outras duas universidades estrangeiras. Pudemos contar também com diversos avaliadores ad hoc que atuaram com pareceres aos trabalhos submetidos à revista ao longo deste ano. Aproveito a oportunidade para agradecer mais uma vez o trabalho voluntário desses pareceristas que ajudam a incrementar a qualidade dos trabalhos da revista, o que sustenta o avanço das áreas de Gestão do Esporte, Lazer e Turismo com um conhecimento cada vez mais robusto. A partir de outubro de 2015 a revista PODIUM Sport, Leisure and Tourism Review contou com mudanças da sua equipe editorial. Assumi a chefia editorial da revista juntamente com o suporte do Diego Janes, novo assistente editorial da revista. Trabalhamos juntos com o assistente editorial Altieres de Oliveira Silva que continua a apoiar a Podium. Aproveito a oportunidade para agradecer ao prof. João Manuel Casquinha Malaia Santos pelos serviços prestados até aqui como editor-chefe da revista e também à Camila de Oliveira Prado pelo apoio oferecido como assistente editorial nesse mesmo período. Os trabalhos prestados por eles devem ser enaltecidos porque foram, sem dúvida, fundamentais para a estruturação da revista e pela legitimação dela perante a comunidade acadêmica. Diante desses novos desafios, apresento os sete trabalhos publicados nesse último número de 2015 da Podium. O primeiro artigo leva o título de “O papel do envolvimento e do orgulho nas decisões de consumo de pacotes de preços: um estudo com ingressos de futebol no Brasil” e tem como autoria Claudio Hoffmann Sampaio, Jefferson Dobner Sordi e Marcelo Gattermann Perin. Neste estudo, os autores identificaram o quanto os pacotes de pre

  20. Principals Of Radiation Toxicology: Important Aspects.

    Science.gov (United States)

    Popov, Dmitri; Maliev, Slava; Jones, Jeffrey

    . 1990, 2012] Moderate and high doses of radiation induces necrosis of radiosensitive cells with the subsequent formation of radiation toxins and their induced acute inflammatory processes. Radiation necrosis is the most substantial and most severe form of radiation induced injury, and when widespread, has grave therapeutic implications. [D. Popov et al. 1990, 2012,Claudio A. et al. 2002, Robertson J. et al. 2002, ] Relatively small doses of Radiation Toxins induce apoptosis and high doses of Radiation Toxins induce necrosis. [Rastogi P. et al. 2009, D. Popov et al. 1990, 2012,] Threshold of Toxic Effects occurs and can be defined. [D. Popov et al. 2012, ] Radiation Toxins affects Somatic cells and Germ Cells. Radiation Toxins can induce teratogenic processes. Specific Toxicity of Radiation Toxins can affects developing fetus. Material and Methods, Results: http://www.intechopen.com/books/current-topics-in-ionizing-radiation-research/radiation-toxins-molecular-mechanisms-of-toxicity-and-radiomimetic-properties- Conclusion: Radiation is a physical agent - induce activation of some secretory proteins with high enzymatic activity. This proteins called as Radiation Toxins can produce specific for radiation biological and toxic effects after administration to radiation naive mammals. [V. Maliev et al. 2007, D. Popov et al. 1990, 2012] Radiation Toxins are teratogenic and oncogenic. Radiation Toxins effects depend on Administered Dose and Radiation effects depend on Exposure Dose and Absorbed Dose. The levels of Radiation Toxins correlates with Radiation Exposure.

  1. Roadway management plan based on rockfall modelling calibration and validation. Application along the Ma-10 road in Mallorca (Spain)

    Science.gov (United States)

    Mateos, Rosa Maria; Garcia, Inmaculada; Reichenbach, Paola; Herrera, Gerardo; Sarro, Roberto; Rius, Joan; Aguilo, Raul

    2016-04-01

    taking into account, not only the success, but also the mistakes. We have further validated the calibrated parameters along the Ma-road using the 63 rockfall recorded during the past 18 years along the road. 81.5% of the rockfalls are well represented by STONE modelling. Results have been exploited by the Road Maintenance Service of Mallorca for the design of the following road management plan: (1) Phase 1. Short-term. Design a specific plan for the road- sections where rockfalls were registered and modelling results were obtained. A large investment will be expended for implementation of retention and protection measures. (2) Phase 2. Medium-term. Design a specific plan for the road- sections where rockfalls were registered but no modelling results were obtained. For these cases, new studies at local scale are necessary as well as the application of other modelling software which include higher resolution input data. (3) Phase 3. Long-term. Design a specific plan for the road- sections where no rockfalls were registered but modelling results were obtained. These are potential rockfall areas and local and specific ground studies are necessaries. References Mateos RM (2006) Los movimientos de ladera en la Serra de Tramuntana (Mallorca). Caracterización geomecánica y análisis de peligrosidad. PhD. Servicio de Publicaciones de la Universidad Complutense de Madrid. Madrid, 299 p. Mateos RM, García-Moreno I, Herrera G, Mulas J (2013) Damage caused by recent mass-movements in Majorca (Spain), a region with a high risk due to tourism.Landslide Science and Practice.Claudio Margottini, Paolo Canuti and KyojiSassa (Editors). Volume 7: Social and Economic Impact and Policies. 105-113. Guzzetti F, Crosta G, Detti R, Agliardi F (2002) STONE: A computer program for the three-dimensional simulation of rock-falls. Computers Geosciences. Vol. 28:1079-1093.

  2. PREFACE: VII Brazilian Congress on Metrology (Metrologia 2013)

    Science.gov (United States)

    Costa-Félix, Rodrigo; Bernardes, Americo; Valente de Oliveira, José Carlos; Mauro Granjeiro, José; Epsztejn, Ruth; Ihlenfeld, Waldemar; Smarçaro da Cunha, Valnei

    2015-01-01

    ) Brazilian National Institute of Metrology, Quality and Technology jcoliveira@inmetro.gov.br José Mauro Granjeiro (Editor on Biotechnology) Brazilian National Institute of Metrology, Quality and Technology jmgranjeiro@inmetro.gov.br Ruth Epsztejn (Editor on Conformity Assessment) Brazilian National Institute of Metrology, Quality and Technology repsztejn@inmetro.gov.br Waldemar Ihlenfeld (Editor on Electrical Metrology) Brazilian National Institute of Metrology, Quality and Technology wgihlenfeld-pronametro@inmetro.gov.br Valnei Smarçaro da Cunha (Editor on Chemistry Metrology) Brazilian National Institute of Metrology, Quality and Technology vscunha@inmetro.gov.br Technical and Scientific Committee for Metrologia 2013 Ado Jório (UFMG) Carlos Achete (UFRJ, Inmetro) Flávio Vasconcelos (UFMG) Giorgio Moscati (USP) Hans Peter Grieneisen (Inmetro) Humberto Brandi (Inmetro) José Carlos Valente de Oliveira (Inmetro) José Guilherme Pereira Peixoto (IRD) José Mauro Granjeiro (Inmetro) Luiz Claudio Moreira Paschoal (Petrobras) Luis Fernado Rust (Inmetro) Luiz Silva Mello (PUC RJ) Marcos Nogueira Eberlin (Unicamp) Oleksii Kuznetsov (Inmetro) Regis Landim (Inmetro) Ricardo Carvalho (ON) Rodrigo Costa-Felix (Inmetro) Romeu José Daroda (Inmetro) Ruth Epsztejn (Inmetro) Valnei Smarçaro da Cunha (Inmetro) Valter Aibe (Inmetro) Waldemar Guilherme Kürten Ihlenfeld (PTB) Wanderley de Souza (UFRJ, Inmetro)

  3. Cannabis and intractable chronic pain: an explorative retrospective analysis of Italian cohort of 614 patients

    Directory of Open Access Journals (Sweden)

    Fanelli G

    2017-05-01

    Full Text Available Guido Fanelli,1,2 Giuliano De Carolis,3 Claudio Leonardi,4 Adele Longobardi,5,6 Ennio Sarli,7,8 Massimo Allegri,1,2 Michael E Schatman9 1Anesthesia, Critical Care and Pain Medicine Unit, Division of Surgical Sciences, Department of Medicine and Surgery, University of Parma, 2Anesthesia, Intensive Care and Pain Therapy Service, Azienda Ospedaliero Universitaria Parma, Parma, 3Pain Therapy Service, Azienda Ospedaliero Universitaria Pisana, Pisa, 4Department of Drug Addiction Diseases, Local Public Health of Rome, Rome, 5Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples “Federico II”, Naples, 6Young Against the Pain (YAP Group, Parma, 7Progetti Live Surgery, 8PinHub Group, Florence, Italy; 9Department of Public Health and Community Medicine, Tufts University School of Medicine, Boston, MA, USA Background: Despite growing interest in the therapeutic use of cannabis to manage chronic pain, only limited data that address these issues are available. In recent years, a number of nations have introduced specific laws to allow patients to use cannabis preparations to treat a variety of medical conditions. In 2015, the Italian government authorized the use of cannabis to treat several diseases, including chronic pain generally, spasticity in multiple sclerosis, cachexia and anorexia among AIDS and cancer patients, glaucoma, Tourette syndrome, and certain types of epilepsy. We present the first snapshot of the Italian experience with cannabis use for chronic pain over the initial year of its use.Methods: This is a retrospective case series analysis of all chronic pain patients treated with oral or vaporized cannabis in six hubs during the initial year following the approval of the new Italian law (December 2015 to November 2016. We evaluated routes of administration, types of cannabis products utilized, dosing, and effectiveness and safety of the treatment.Results: As only one of the six centers has

  4. Low-dose oral prolonged-release oxycodone/naloxone for chronic pain in elderly patients with cognitive impairment: an efficacy–tolerability pilot study

    Directory of Open Access Journals (Sweden)

    Petrò E

    2016-03-01

    Full Text Available Emiliano Petrò,1 Elena Ruffini,1 Melania Cappuccio,2 Valeria Guerini,2 Gloria Belotti,3 Sara Fascendini,4 Cristina Licini,4 Claudio Marcassa51Rehabiliation and Alzheimer Unit, San Pietro Polyclinic, Ponte San Pietro, 2Alzheimer Center, P. Gusmini Foundation, Vertova, 3Santa Maria Ausiliatrice Foundation, Bergamo, 4Alzheimer Center, Briolini Hospital FERB ONLUS, Gazzaniga, 5Cardiology, Maugeri Foundation IRCCS, Veruno, ItalyObjective: This pilot study evaluated the efficacy and safety of prolonged-release oxycodone/naloxone (OXN-PR in older subjects with chronic pain and mild-to-moderate cognitive impairment.Methods: This was a prospective, observational, open-label study of 45-day duration. Patients with moderate-to-severe chronic pain and naïve to strong opioids were recruited from nursing homes and Alzheimer’s disease centers. OXN-PR was initiated at low doses (5 mg od or bid and increased to a maximum of 20 mg bid. The primary efficacy endpoint was a pain intensity reduction of ≥30% from baseline (T0 to 15 days after OXN-PR initiation, as assessed by a numerical rating scale or the Pain Assessment in Advanced Dementia scale. Other assessments included the Barthel activities of daily living index, Neuropsychiatric Inventory, Bowel Function Index, and adverse events.Results: The analysis included 53 patients (mean age, 83.0 years; mean Mini-Mental State Examination score, 18.6 with severe pain (median Numerical Rating Scale/Pain Assessment in Advanced Dementia 6 and substantial impairment in daily functioning (mean Barthel index, 32.2. The primary endpoint was achieved by 92.4% of patients. OXN-PR significantly reduced mean pain intensity from baseline to study end (numerical rating scale, 6.6±1.0 vs 2.3±1.1, P<0.0001; Pain Assessment in Advanced Dementia, 6.9±1.6 vs 0.9±0.8, P<0.0001. Substantial improvements from T0 to T45 in daily functioning (mean Barthel index, 32.2±16.8 vs 53.7±23.9, P<0.0001 and neuropsychiatric symptoms

  5. Randomized clinical trial comparing manual suture and different models of mechanical suture in the mimicking of bariatric surgery in swine

    Directory of Open Access Journals (Sweden)

    Fernandes MA

    2014-02-01

    Full Text Available Marcos AP Fernandes,1 Bruno MT Pereira,2 Sandra M Guimarães,1 Aline Paganelli,3 Carlos Manoel CT Pereira,1 Claudio Sergio Batista4 1Institute of Obesity and Advanced Video Laparoscopic Surgery of Petropolis, Rio de Janeiro, Brazil; 2Division of Trauma, University of Campinas, São Paulo, Brazil; 3Laboratório de Patologia Micron Cell Diagnóstico, Rio de Janeiro, Brazil; 4Department of Gynecology and Obstetrics, Faculty of Medicine of Petropolis, Rio de Janeiro, Brazil Context and objective: Variations in the ability of surgeons served as motivation for the development of devices that, overcoming individual differences, allow the techniques to be properly performed, and of which the end result was the best possible. Every technique must be reproduced reliably by the majority of surgeons for their results to be adopted and recognized as effective. The aim of this study was to compare the results, from the point of view of anatomic pathology, of manual sutures versus mechanical sutures using different models of linear mechanical staplers, in the procedure of gastroenteroanastomosis and enteroanastomosis in swine. Methods: Thirty-six healthy, adult, male Sus scrofa domesticus pigs, weighing between 20.7 and 25.5 kg, were used. The swine were randomly divided into four groups of nine pigs, according to the type of suture employed: group A, manual suture with Polysorb® 3-0 wire; group B, 80-shear linear stapler (Covidien® Gia 8038-S; group C, 75-shear linear stapler (Ethicon® Tlc 75; and group D, 75-shear linear stapler (Resource® Yq 75-3. A temporal study was established on the seventh postoperative day for histopathological analysis, and the degree of inflammation, fibrosis, and newly formed vessels, as well as the presence or absence of granulation tissue, foreign body granuloma, and necrosis were all evaluated qualitatively and semiquantitatively. The results were analyzed statistically. Results: Observations during the histopathological

  6. Prognostic value of ferritin, neuron-specific enolase, lactate dehydrogenase, and urinary and plasmatic catecholamine metabolites in children with neuroblastoma

    Directory of Open Access Journals (Sweden)

    Cangemi G

    2012-11-01

    Full Text Available Giuliana Cangemi,1 Giorgio Reggiardo,2 Sebastiano Barco,1 Laura Barbagallo,1 Massimo Conte,3 Paolo D'Angelo,4,# Maurizio Bianchi,5,# Claudio Favre,6,# Barbara Galleni,3 Giovanni Melioli,1 Riccardo Haupt,7 Alberto Garaventa,3 Maria V Corrias81Clinical Pathology Laboratory Unit, Giannina Gaslini Institute, Genoa, Italy; 2Data Management and Biostatistics Unit, Medi Service, Genoa, Italy; 3Department of Hematology-Oncology, Giannina Gaslini Institute, Genoa, Italy; 4Pediatric Oncology Unit, Azienda Civico, Di Cristina e Benfratelli, Palermo, Italy; 5Pediatric Onco-Hematology, Stem Cell Transplantation and Cellular Therapy Division, Regina Margherita Children's Hospital, Turin, Italy; 6Department of Hematology-Oncology, Pisana University Hospital, Pisa, Italy; 7Epidemiology and Biostatistics Unit, Giannina Gaslini Institute, Genoa, Italy; 8Laboratory of Oncology, Giannina Gaslini Institute, Genoa, Italy#On behalf of the Italian Association of Pediatric Hematology and Oncology (AIEOPAbstract: Different plasma and urinary parameters have been tested as valuable prognostic markers for children with neuroblastoma (NB, but conclusive results from multivariate analyses are still lacking. Samples collected at diagnosis from 505 patients diagnosed in Italy between June 1994 and November 2010 were analyzed at the Italian reference laboratory according to standard methodologies. Patient clinical data were retrieved from the Italian NB Registry. For statistical analysis, patients were grouped according to stage, age, MYCN status, and outcome. Cumulative survival was calculated by the Kaplan–Meier procedure using the first quartile of the marker distribution as a cut-off value to stratify the patients. Multivariate analysis was performed by the Cox regression model by considering only the significant variables. When the entire cohort of patients was considered, none of the different parameters had an independent prognostic value. However, in patients with

  7. PREFACE: International Conference on Computing in High Energy and Nuclear Physics (CHEP 2010)

    Science.gov (United States)

    Lin, Simon C.; Shen, Stella; Neufeld, Niko; Gutsche, Oliver; Cattaneo, Marco; Fisk, Ian; Panzer-Steindel, Bernd; Di Meglio, Alberto; Lokajicek, Milos

    2011-12-01

    , as well as two banquets held at the Grand Hotel and Grand Formosa Regent in Taipei. The next CHEP conference will be held in New York, the United States on 21-25 May 2012. We would like to thank the National Science Council of Taiwan, the EU ACEOLE project, commercial sponsors, and the International Advisory Committee and the Programme Committee members for all their support and help. Special thanks to the Programme Committee members for their careful choice of conference contributions and enormous effort in reviewing and editing about 340 post conference proceedings papers. Simon C Lin CHEP 2010 Conference Chair and Proceedings Editor Taipei, Taiwan November 2011 Track Editors/ Programme Committee Chair Simon C Lin, Academia Sinica, Taiwan Online Computing Track Y H Chang, National Central University, Taiwan Harry Cheung, Fermilab, USA Niko Neufeld, CERN, Switzerland Event Processing Track Fabio Cossutti, INFN Trieste, Italy Oliver Gutsche, Fermilab, USA Ryosuke Itoh, KEK, Japan Software Engineering, Data Stores, and Databases Track Marco Cattaneo, CERN, Switzerland Gang Chen, Chinese Academy of Sciences, China Stefan Roiser, CERN, Switzerland Distributed Processing and Analysis Track Kai-Feng Chen, National Taiwan University, Taiwan Ulrik Egede, Imperial College London, UK Ian Fisk, Fermilab, USA Fons Rademakers, CERN, Switzerland Torre Wenaus, BNL, USA Computing Fabrics and Networking Technologies Track Harvey Newman, Caltech, USA Bernd Panzer-Steindel, CERN, Switzerland Antonio Wong, BNL, USA Ian Fisk, Fermilab, USA Niko Neufeld, CERN, Switzerland Grid and Cloud Middleware Track Alberto Di Meglio, CERN, Switzerland Markus Schulz, CERN, Switzerland Collaborative Tools Track Joao Correia Fernandes, CERN, Switzerland Philippe Galvez, Caltech, USA Milos Lokajicek, FZU Prague, Czech Republic International Advisory Committee Chair: Simon C. Lin , Academia Sinica, Taiwan Members: Mohammad Al-Turany , FAIR, Germany Sunanda Banerjee, Fermilab, USA Dario Barberis, CERN

  8. Spinal cord stimulation or prostacyclin in unrevascularizable arteriopathy of lower limbs (SPINAL study: interim analysis results

    Directory of Open Access Journals (Sweden)

    Pedrini L

    2014-04-01

    Full Text Available Luciano Pedrini,1 Maria Sandra Ballestrazzi,1 Fabio Chierichetti,2 Luigi Comandatore,3 Filippo Magnoni,1 Reinhold Perkmann,4 Tommaso Castrucci,5 Domenico Palombo6On behalf of the SPINAL Study Group1Operative Unit of Vascular Surgery, Maggiore Hospital of Bologna, Bologna, Italy; 2Operative Unit of Vascular Surgery, Circle Hospital of Busto Arsizio, Busto Arsizio, Italy; 3Operative Unit of Vascular Surgery, AEO Morelli of Sondalo, Sondalo, Italy; 4Operative Unit of Vascular and Thoracic Surgery, Hospital of Bolzano, Bolzano, Italy; 5Operative Unit of Vascular Surgery of Sant'Eugenio Hospital, Rome, Italy; 6Operative Unit of Vascular and Endovascular Surgery, IRCCS San Martino, Genoa, ItalyObjective: The aim of this study was to compare the clinical efficacy and the safety of spinal cord stimulation (SCS plus medical treatment versus iloprost plus medical treatment in patients with severe unrevascularizable ischemia of the lower limbs due to atherosclerotic disease of the limbs and to identify predictive parameters for a positive outcome of SCS.Methods: A multicenter randomized controlled trial (RCT with central randomization and core laboratory evaluation of angiography, subdivided into two treatment arms (SCS and iloprost and two subgroups (rest pain and ulcer/gangrene. After the 15-day clinical efficacy evaluation, responder patients continued follow-up in their arm, while nonresponders could change arms or decline participation. The primary endpoint was 1-year limb salvage. Principal secondary endpoints were: survival rate; minor amputations and stump healing; ulcer healing; pain relief and analgesic intake; and predictive criteria for SCS treatment.Results: The trial was stopped at 35.6% of the expected sample due to low accrual rate. Fifty-two patients (55 legs entered the study. At the 15-day efficacy evaluation, responders (reduced pain, no increase of ulcer area comprised 74% of the SCS arm and 26% of the iloprost arm, (P=0.003. Nine

  9. Controllable Quantum States Mesoscopic Superconductivity and Spintronics (MS+S2006)

    Science.gov (United States)

    Takayanagi, Hideaki; Nitta, Junsaku; Nakano, Hayato

    2008-10-01

    Mesoscopic effects in superconductors. Tunneling measurements of charge imbalance of non-equilibrium superconductors / R. Yagi. Influence of magnetic impurities on Josephson current in SNS junctions / T. Yokoyama. Nonlinear response and observable signatures of equilibrium entanglement / A. M. Zagoskin. Stimulated Raman adiabatic passage with a Cooper pair box / Giuseppe Falci. Crossed Andreev reflection-induced giant negative magnetoresistance / Francesco Giazotto -- Quantum modulation of superconducting junctions. Adiabatic pumping through a Josephson weak link / Fabio Taddei. Squeezing of superconducting qubits / Kazutomu Shiokawa. Detection of Berrys phases in flux qubits with coherent pulses / D. N. Zheng. Probing entanglement in the system of coupled Josephson qubits / A. S. Kiyko. Josephson junction with tunable damping using quasi-particle injection / Ryuta Yagi. Macroscopic quantum coherence in rf-SQUIDs / Alexey V. Ustinov. Bloch oscillations in a Josephson circuit / D. Esteve. Manipulation of magnetization in nonequilibrium superconducting nanostructures / F. Giazotto -- Superconducting qubits. Decoherence and Rabi oscillations in a qubit coupled to a quantum two-level system / Sahel Ashhab. Phase-coupled flux qubits: CNOT operation, controllable coupling and entanglement / Mun Dae Kim. Characteristics of a switchable superconducting flux transformer with a DC-SQUID / Yoshihiro Shimazu. Characterization of adiabatic noise in charge-based coherent nanodevices / E. Paladino -- Unconventional superconductors. Threshold temperatures of zero-bias conductance peak and zero-bias conductance dip in diffusive normal metal/superconductor junctions / Iduru Shigeta. Tunneling conductance in 2DEG/S junctions in the presence of Rashba spin-orbit coupling / T. Yokoyama. Theory of charge transport in diffusive ferromagnet/p-wave superconductor junctions / T. Yokoyama. Theory of enhanced proximity effect by the exchange field in FS bilayers / T. Yokoyama. Theory of

  10. EMRS Spring Meeting 2014 Symposium D: Phonons and fluctuations in low dimensional structures

    Science.gov (United States)

    2014-11-01

    . Goettingen) poster title ''Phonon blocking in Multilayers produced by Pulsed Laser Deposition'', Jordi Gomis-Bresco et al. (ICN2) poster '' A 1D PhoXonic Crystal'', Barcelona and Benjamin J Robinson et al. (U. Lancaster) poster ''Scanning Thermal microscopy studies of 2D materials''. The symposium organisers are grateful to the Scientific Committee members, Prof. Bahram Djafari-Rouhani (France), Prof. Dr. Thomas Dekorsy (Germany), Prof. Anthony Kent (UK), Prof. Fabio Marchesoni (Italy), Dr. Natalio Mingo (France), Prof. Pascal Ruello, (France) and Prof. Javier Viejo-Rodriguez (Spain), for their help with all aspects of evaluation of the scientific level of the presentations in the symposium. The symposium was sponsored by the FP7 ICT FET Open Coordination Action EUPHONON (GA. 612086) and by the CNRS GDR ''Thermal Nanosciences and NanoEngineering''. The symposium organisers express their sincere thanks to the staff of the E-MRS for continuous support and timely advice in all organisational aspects. We are indebted to Dr. Erwan Guillotel (ICN2) for his assistance with the organisation of the symposium.

  11. XMM-Newton detects X-ray 'solar cycle' in distant star

    Science.gov (United States)

    2004-05-01

    other stars as well. A team of astronomers, led by Fabio Favata, from ESA's European Space Research and Technology Centre, The Netherlands, has monitored a small number of solar-type stars since the beginning of the XMM-Newton mission in 2000. The X-ray brightness of HD 81809, a star located 90 light years away in the constellation Hydra (the water snake), has varied by more than 10 times over the past two and a half years, reaching a well defined peak in mid 2002. The star has shown the characteristic X-ray modulation (brightening and dimming) typical of the solar cycle. "This is the first clear sign of a cyclic pattern in the X-ray emission of stars other than the Sun," said Favata. Furthermore, the data show that these variations are synchronised with the starspot cycle. If HD 81809 behaves like the Sun, its X-ray brightness can vary by a factor of one hundred over a few years. "We might well have caught HD 81809 at the beginning of an X-ray activity cycle," added Favata. The existence of starspot cycles on other stars had already been established long ago, thanks to observations that began in the 1950s. However, scientists did not know whether the X-ray radiation would also vary with the number of starspots. ESA's XMM-Newton has now shown that this is indeed the case and that this cyclic X-ray pattern is not typical of the Sun alone. "This suggests that our Sun's behaviour is probably nothing exceptional," said Favata. Besides its interest for scientists, the Sun's cyclical behaviour can have an influence on everyone on Earth. Our climate is known to be significantly affected by the high-energy radiation emitted by the Sun. For instance, a temporary disappearance of the solar cycle in the 18th century corresponded with an exceptionally cold period on Earth. Similarly, in the early phases of the lifetime of a planet, this high-energy radiation has a strong influence on the conditions of the atmosphere, and thus potentially on the development of life. Finding out

  12. Five-year review of an international clinical research-training program

    Directory of Open Access Journals (Sweden)

    Suemoto CK

    2015-04-01

    Full Text Available Claudia Kimie Suemoto,1,2 Sherine Ismail,1,3 Paulo César Rodrigues Pinto Corrêa,1,4,5 Faiza Khawaja,1,6 Teodoro Jerves,1 Laura Pesantez,1 Ana Claudia Camargo Gonçalves Germani,1,7 Fabio Zaina,1,8 Augusto Cesar Soares dos Santos Junior,1,9,10 Ricardo Jorge de Oliveira Ferreira,1,11 Priyamvada Singh,1,12 Judy Vicente Paulo,1,13 Suely Reiko Matsubayashi,1,14 Liliane Pinto Vidor,1,15 Guilherme Andretta,1,16 Rita Tomás,1,17 Ben MW Illigens,1,18 Felipe Fregni1,18,19 1Collaborative Learning in Clinical Research Program, Principles and Practice of Clinical Research (PPCR, Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital and Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; 2Discipline of Geriatrics, Department of Internal Medicine, University of São Paulo Medical School, São Paulo, Brazil; 3King Abdullah International Medical Research Center, King Saud bin Abdulaziz University for Health Sciences, Pharmaceutical Care Department, King Khalid Hospital, NGHA, Jeddah, Saudi Arabia; 4Discipline of Internal Medicine and Medical Semiology, Department of Internal Medicine, Federal University of Ouro Preto (UFOP Medical School, Ouro Preto, Brazil; 5Discipline of Pneumology, Department of Internal Medicine, Centro Universitário de Belo Horizonte (Uni-BH, Belo Horizonte, Brazil; 6Canadian Centre for Advanced Eye Therapeutics, Mississauga, ON, Canada; 7Department of Preventive Medicine, University of São Paulo Medical School, São Paulo, Brazil; 8Italian Scientific Spine Institute (ISICO, Milan, Italy; 9Hospital Osvaldo Rezende Franco, Betim, Brazil; 10Nucleo de Avaliação de Tecnologia em Saude, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; 11Department of Rheumatology, Centro Hospitalar e Universitário de Coimbra, Coimbra, Portugal; 12Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA; 13Portuguese Institute of Oncology, Coimbra, Portugal; 14Acupuncture

  13. Comentario a la presentación del libro "70 años del Cáncer en Colombia" del Académico Efraim Otero Ruiz

    Directory of Open Access Journals (Sweden)

    Alfonso Latiff Conde

    2002-08-01

    Full Text Available

    Estoy maravillado con el monumental esfuerzo y trabajo de Efraim Otero-Ruiz en la producción de su portentoso libro “Setenta años del cáncer en Colombia”.

    Escrito en una prosa amena y armoniosa, su lectura es verdadero deleite intelectual para quien sigue la apasionante madeja que constituye toda la trama inicial y que envuelve la concepción, el nacimiento y el desarrollo de una institución para el tratamiento del cáncer en Colombia.

    Es apasionante la forma como Efraim toma el hilo de la historia desde sus primeras y más importantes incepciones.

    Es sin duda Claudio Regaud, Jefe del Laboratorio de Radiofisiología del Instituto de Radium de París, la figura clave en la iniciativa de creación de un Instituto de Radium en Colombia. Alfonso Esguerra Gómez, becario de la Institución adquiere una valiosa experiencia en el tratamiento de tumores superficiales de cara y cuello y descubre la famosa pasta Colombia que permite amoldarse sobre la piel mientras en su interior se colocan las agujas de radium.

    En la década de los veinte Regaud se convierte en la figura más prestante en el mundo en el manejo del radium y es invitado universalmente para comunicar no solo sus experiencias sino como consejero y orientador de la creación de institutos de radium en el mundo.

    La invitación a Regaud en 1928 para visitar el Perú es conocida por Alfonso Esguerra y allí por primera vez se organiza un movimiento de influencias que con agudo análisis describe Efraim Otero, para movilizar todas las fuerzas académicas y políticas con el fin de aprovechar esta oportunidad y obtener la visita de Regaud a Colombia.

    En varias ocasiones en el futuro, circunstancias similares harán necesaria la influencia de médicos, no solo eminentes sino dotados de excelentes conexiones sociales y políticas para crear el Instituto Nacional de Radium.

    Efraím se introduce por todos los vericuetos académicos, cient

  14. Apresentação

    Directory of Open Access Journals (Sweden)

    Os Editores

    2013-12-01

    com o movimento cultural e político que faz a revisão da história da criação de Israel. Por fim, o último artigo do dossiê, o de Ignacio Del Valle Dávila e Carolina Amaral de Aguiar, traz as visões complementares sobre o primeiro ano do governo da Unidade Popular (1970-1973 do presidente Salvador Allende presente em Compañero presidente (Miguel Littin, 1971 e El diálogo de América (Álvaro Covacevich, 1972, realçando as tensões ideológicas decorrentes das visões que a esquerda tinha da experiência chilena. Na seção de artigos livres, Arilson Oliveira recupera o sentido histórico da rosa e do riso a propósito de O Nome da Rosa (1986, de Jean-Jacques Annaud. Claudio Coração identifica os aspectos relacionados ao problema da comunicação em Amores Brutos (2000, 21 Gramas (2003 e Babel (2006, de Alejandro González Iñárritu. Roberta Veiga recompõe o desenho do mecanismo fílmico de Jean-Luc Godard, em Passion (1982, a partir da pintura, da discussão sobre o tempo e do político. Rodrigo Carreiro analisa como os falsos documentários de horror codificados como found footage tem sido massivamente realizados nas últimas duas décadas. Por fim, André Brasil se dedica ao exame do conceito de antecampo pensado a partir de dois documentários - Pi’õnhitsi  e  Mokoi Tekoá Petei Jeguatá , vinculados ao cinema indígena da equipe Vídeo das Aldeias.A Revista dá continuidade neste número à seção de resenhas, valorizando o debate em torno da produção acadêmica recente. Boa leitura! Os editores

  15. BAELO CLAUDIA Y POLLENTIA: NUEVAS EVIDENCIAS SOBRE LAS FLUCTUACIONES ECONÓMICAS EN LA HISPANIA ROMANA DE LOS SIGLOS I-II D. C. (Baelo Claudia and Pollentia: new evidence on the economic fluctuations in Roman Spain during the first and second centuries AD

    Directory of Open Access Journals (Sweden)

    Pascual Izquierdo-Egea

    2012-06-01

    Full Text Available La revisión cronológica de la necrópolis sureste de Baelo Claudia (Bolonia-Tarifa, Cádiz y la de Can Fanals, en Pollentia (Alcudia, Mallorca, ha permitido ampliar el conocimiento sobre las fluctuaciones económicas en la Hispania romana de los siglos I y II de nuestra era y los cambios sociales asociados a las mismas. Se ha obtenido una nueva confirmación del impacto de la gran crisis de tiempos de Tiberio en los registros funerarios de Baelo Claudia y Pollentia, detectada previamente en Ampurias o Emporiae (Gerona. La bonanza de la época de Claudio se puede comprobar en Baelo Claudia de forma más elocuente que en Emporiae. Ahora bien, esta coincidencia en el devenir económico se rompe a lo largo de la segunda mitad del siglo I d. C., en concreto durante el periodo comprendido entre Nerón y principios de los Flavios. Es entonces cuando, frente a la decadente Ampurias, una pujante Pollentia sigue los pasos de la opulenta Baelo mostrando su mayor prosperidad. Sin embargo, esas tres ciudades romanas de Hispania mantienen un claro nexo basado en la exhibición durante ese periodo de su máxima complejidad social. Siempre se da una proporción directa entre la acumulación económica amortizada en los ajuares y la diferenciación entre los individuos, salvo en dos casos excepcionales. Uno, ya conocido, se refiere a la Ampurias de la segunda mitad del siglo I d. C., donde el empobrecimiento que la caracteriza se asocia con un incremento de la distancia social. Y, el otro, corresponde al extraño fenómeno documentado en la Pollentia del siglo II d. C. En esta sigue creciendo el gasto funerario, pero la diferenciación social medida desciende durante la primera mitad hasta caer abruptamente a lo largo de la segunda parte de dicha centuria. No obstante, lo más importante es que, por ahora, se detecta la misma evolución de la diferenciación social en Emporiae, Baelo Claudia y Pollentia desde la época de Tiberio hasta la primera mitad del

  16. PREFACE: Workshop Photograph and Program

    Science.gov (United States)

    2011-07-01

    Workshop photograph Workshop Program Sunday 28 March 201019:00-21:00 Reception at Okura Frontier Hotel Tsukuba(Buffet style dinner with drink) Monday 29 March 2010Introduction (Chair: André Rubbia (ETH Zurich))09:00 Welcome address (05') Atsuto Suzuki (KEK)09:05 Message from CERN on neutrino physics (10') Sergio Bertolucci (CERN)09:15 Message from FNAL on neutrino physics (10') Young Kee Kim (FNAL)09:25 Message from KEK on neutrino physics (10') Koichiro Nishikawa (KEK)09:35 Introductory remark on GLA2010 (10') Takuya Hasegawa (KEK) Special session (Chair: Koichiro Nishikawa (KEK))09:45 The ICARUS Liquid Argon TPC (45') Carlo Rubbia (CERN)10:30-11:00 Coffee break Main goals of Giant Liquid Argon Charge Imaging Experiments I (Chair: Takashi Kobayashi (KEK))11:00 Results from massive underground detectors (non accelerator) (30') Takaaki Kajita (ICRR, U. of Tokyo)11:30 Present long baseline neutrino experiments (30') Chang Kee Jung (SUNY Stony Brook)12:00-12:10 Workshop picture12:10-14:00 Lunch break Main goals of Giant Liquid Argon Charge Imaging Experiments II (Chair: Takashi Kobayashi (KEK))14:00 Physics goals of the next generation massive underground experiments (30') David Wark (Imperial College London)14:30 Near detectors for long baseline neutrino experiments (20') Tsuyoshi Nakaya (Kyoto U.) Lessons on Liquid Argon Charge Imaging technology from ongoing developments (Chair: Chang Kee Jung (SUNY Stony Brook))14:50 WARP (30') Claudio Montanari (U. of Pavia)15:20 ArDM (30') Alberto Marchionni (ETH Zurich)15:50 From ArgoNeuT to MicroBooNE (30') Bonnie Fleming (Yale U.)16:20 250L (30') Takasumi Maruyama (KEK)16:50 The DEAP/CLEAN project (20') Mark Boulay (Queen's U.)17:10-17:40 Coffee break Lessons from Xe based Liquids Imaging detectors (Chair: Flavio Cavanna (U. of L'Aquilla))17:30 MEG (20') Satoshi Mihara (KEK)17:50 The XENON project (20') Elena Aprile (Columbia U.)18:10 XMASS (20') Hiroyuki Sekiya (ICRR, U. of Tokyo) Studies on physics performance (Chair

  17. Reseñas de Libros

    Directory of Open Access Journals (Sweden)

    José Miguel Delgado Idarreta

    2009-12-01

    Full Text Available Andrés Cabello, Sergio; Capellán de Miguel, Gonzalo; Fandiño Pérez, Roberto y Orduña Prada, Mónica, La transición a la democracia en La Rioja. Logroño, Gobierno de La Rioja, 2001, 291 pp.Páginas 199-200José Miguel Delgado IdarretaBeneyto, José María; Martín de la Guardia, Ricardo y Pérez Sánchez, Guillermo (dirs., Europa y Estados Unidos. Una historia de la relación atlántica en los últimos cien años. Madrid, Biblioteca Nueva, 2005, 356 pp.Páginas 201-203David Molina RabadánBosworth, Richard J. B., Mussolini’s Italy. Life under the Fascist Dictatorship 1915-1945. New York, Penguin, 2006, 692 pp.Páginas 203-205Jan NelisDávila A., Mireya; Fuentes S., Claudio (eds., Promesas de cambio. Izquierda y derecha en el Chile contemporáneo. Santiago de Chile, Editorial Universitaria, FLACSO, 2003, 189 pp.Páginas 205-208David Oviedo SilvaDelgado Idarreta, José Miguel; Andrés Cabello, Sergio, Actas del V Simposio de Historia Actual: La Rioja, España, Europa. Logroño, Instituto de Estudios Riojanos, 2006, 449 pp.Páginas 208-212Alfonso Pinilla GarcíaEvans, Richard J., La llegada del Tercer Reich. Barcelona, Península, 2005, 672 pp.Páginas 212-214Alejandro Piñero GonzálezFriedman, Thomas L., La Tierra es plana. Breve historia del mundo globalizado del siglo XXI. Madrid, Martínez Roca, 2006, 496 pp.Páginas 214-216David Molina RabadánGil Calvo, Enrique, El miedo es el mensaje. Riesgo, incertidumbre y medios de comunicación. Madrid, Alianza Editorial, 2004, 320 pp.Páginas 216-218Lucía Benítez EyzaguirreGoicovic Donoso, Igor, Entre el dolor y la ira. La venganza de Antonio Ramón Ramón. Chile, 1914. Osorno, Editorial Universidad de los Lagos, 2005, 188 pp.Páginas 218-221Alejandra Brito PeñaGriffin, Roger (ed., Fascism, Totalitarianism and Political Religion. New York, Routledge, 2005, 225 pp.Páginas 221-222Jan NelisMcNeill, John R., Algo nuevo bajo el Sol. Historia medioambiental del mundo en el siglo XX. Alianza

  18. Normas para colaboração

    Directory of Open Access Journals (Sweden)

    Helmut Renders

    2009-10-01

    da ABNT,2002. Seguem alguns exemplos:Livro:SOBRENOME DO/A AUTOR/A, prenome. Título da obra: subtítulo. Númeroda edição se não for a primeira, Local de publicação, estado: editora, data.RIBEIRO, Claudio de Oliveira et all. (orgs.. Teologia e prática na tradição wesleyena: Uma leitura a partir da América Latina e Caribe. São Bernardo do Campo, SP: Editeo, 2005.Artigo:SOBRENOME DO/A AUTOR/A, prenome. “Título do artigo”. In: Título doperiódico, número da edição, páginas (data.PAULA, Blanches de. “Luto e existência”. In: Caminhando, vol. 11, n. 17, p. 105-114 (2006.Coletânea:SOBRENOME DO/A AUTOR/A, prenome. “Título do capítulo”. In: iniciais do nome seguidas do sobrenome do organizador. Título da coletânea. Número da edição quando não for a primeira. Local de publicação, Estado: editora, data.MENDONÇA, Antonio Gouvêa “Ciência(s da Religião: Teoria e pós-graduação no Brasil”. F. Teixeira. A(s ciência(s da religião no Brasil: afirmação de uma área acadêmica. São Paulo, SP: Paulinas, 2001.Referências da Internet:Acresce-se, depois da citação do livro ou do artigo: Disponível em: . Acesso em: dia[s]/mês/ano (somente números.RAUSCHENBUSCH, Walter. For God and the People. Prayers of the SocialAwakening. Boston, New York, Chicago: The Pilgrim Press, 1910. Disponível em: .Acesso em: 20/03/2009.

  19. GUIDELINES FOR THE DIAGNOSIS AND MANAGEMENT OF SYNCOPE (2009

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    Angel Moya

    2010-01-01

    Full Text Available Внешние эксперты: Haruhiko Abe (Япония, David G. Benditt (США, Wyatt W. Decker (США, Blair P. Grubb (США, Horacio Kaufmann9 (США, Carlos Morillo (Канада, Brian Olshansky (США, Steve W. Parry (Великобритания, Robert Sheldon (Канада, Win K. Shen (СШАЧлены Комитета Европейского общества кардиологов по практическим рекомендациям (ESC Committee for Practice Guidelines: CPG: Alec Vahanian (Председатель (Франция, Angelo Auricchio (Швейцария,Jeroen Bax (Нидерланды, Claudio Ceconi (Италия, Veronica Dean (Франция, Gerasimos Filippatos (Греция, Christian Funck-Brentano (Франция, Richard Hobbs (Великобритания, Peter Kearney (Ирландия, Theresa McDonagh (Великобритания, Keith McGregor (Франция, Bogdan A. Popescu (Румыния, Zeljko Reiner (Хорватия, Udo Sechtem (Германия, Per Anton Sirnes (Норвегия, Michal Tendera (Польша, Panos Vardas (Греция, Petr Widimsky (ЧехияРецензенты: Angelo Auricchio (Координатор от CPG (Швейцария, Esmeray Acarturk (Турция, Felicita Andreotti (Италия, Riccardo Asteggiano (Италия, Urs Bauersfeld (Швейцария, Abdelouahab Bellou4 (Франция, Athanase Benetos6 (Франция, Johan Brandt (Швеция, Mina K. Chung3 (США, Pietro Cortelli 8 (Италия, Antoine Da Costa (Франция, Fabrice Extramiana (Франция, Jose´ Ferro7 (Португалия, Bulent Gorenek (Турция, Antti Hedman (Финляндия, Rafael Hirsch (Израиль, Gabriela Kaliska (Словакия, Rose Anne Kenny6 (Ирландия, Keld Per Kjeldsen (Дания, Rachel Lampert 3 (USA, Henning Mølgard (Denmark, Rain Paju (Эстония, Aras Puodziukynas (Литва, Antonio Raviele (

  20. Study on antibacterial alginate-stabilized copper nanoparticles by FT-IR and 2D-IR correlation spectroscopy

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    Díaz-Visurraga J

    2012-07-01

    Full Text Available Judith Díaz-Visurraga,1,2 Carla Daza,2 Claudio Pozo,2 Abraham Becerra,2 Carlos von Plessing,1,2 Apolinaria García31Department of Pharmacy, Faculty of Pharmacy, University of Concepcion; 2Research Center of Advanced Polymers (CIPA, CONICYT REGIONAL/CIPA R08C1002; 3Department of Microbiology, Faculty of Biological Sciences, University of Concepcion, Concepción, ChileBackground: The objective of this study was to clarify the intermolecular interaction between antibacterial copper nanoparticles (Cu NPs and sodium alginate (NaAlg by Fourier transform infrared spectroscopy (FT-IR and to process the spectra applying two-dimensional infrared (2D-IR correlation analysis. To our knowledge, the addition of NaAlg as a stabilizer of copper nanoparticles has not been previously reported. It is expected that the obtained results will provide valuable additional information on: (1 the influence of reducing agent ratio on the formation of copper nanoparticles in order to design functional nanomaterials with increased antibacterial activity, and (2 structural changes related to the incorporation of Cu NPs into the polymer matrix.Methods: Cu NPs were prepared by microwave heating using ascorbic acid as reducing agent and NaAlg as stabilizing agent. The characterization of synthesized Cu NPs by ultraviolet visible spectroscopy, transmission electron microscopy (TEM, electron diffraction analysis, X-ray diffraction (XRD, and semiquantitative analysis of the weight percentage composition indicated that the average particle sizes of Cu NPs are about 3–10 nm, they are spherical in shape, and consist of zerovalent Cu and Cu2O. Also, crystallite size and relative particle size of stabilized Cu NPs were calculated by XRD using Scherrer’s formula and FT from the X-ray diffraction data. Thermogravimetric analysis, differential thermal analysis, differential scanning calorimetry (DSC, FT-IR, second-derivative spectra, and 2D-IR correlation analysis were applied to

  1. РЕКОМЕНДАЦИИ ПО ЛЕЧЕНИЮ ОСТРОГО КОРОНАРНОГО СИНДРОМА БЕЗ СТОЙКОГО ПОДЪЕМА СЕГМЕНТА ST

    Directory of Open Access Journals (Sweden)

    2012-01-01

    Full Text Available Члены комитета по практическим рекомендациям: Jeroen J. Bax (председатель (Нидерланды, Angelo Auricchio (Швейцария, Helmut Baumgartner (Германия, Claudio Ceconi (Италия, Veronica Dean (Франция, Christi Deaton (Великобритания, Robert Fagard (Бельгия, Christian Funck-Brentano (Франция, David Hasdai (Израиль, Arno Hoes (Нидерланды, Juhani Knuuti (Финляндия, Philippe Kolh (Бельгия, Theresa McDonagh (Великобритания,Cyril Moulin (Франция, Don Poldermans (Нидерланды, Bogdan A. Popescu (Румыния, Zeljko Reiner (Хорватия, Udo Sechtem (Германия, Per Anton Sirnes (Норвегия, Adam Torbicki (Польша, Alec Vahanian (Франция, Stephan Windecker (Швейцария Рецензенты: Stephan Windecker (координатор (Швейцария, Stephan Achenbach (Германия, Lina Badimon (Испания, Michel Bertrand (Франция, Hans Erik Bøtker (Дания, Jean-Philippe Collet (Франция, Filippo Crea (Италия, Nicolas Danchin (Франция, Erling Falk (Дания, John Goudevenos (Греция, Dietrich Gulba (Германия, Rainer Hambrecht (Германия, Joerg Herrmann (США, Adnan Kastrati (Германия, Keld Kjeldsen (Дания, Steen Dalby Kristensen(Дания, Patrizio Lancellotti (Бельгия, Julinda Mehilli (Германия, Bela Merkely (Венгрия, Gilles Montalescot (Франция, Franz-Josef Neumann (Германия, Ludwig Neyses (Великобритания, Joep Perk (Швеция, Marco Roffi (Швейцария, Francesco Romeo (Италия, Mikhail Ruda (Россия, Eva Swahn (Швеция, Marco Valgimigli (Италия, Christiaan JM Vrints (Бельгия, Petr Widimsky (Чешская республика

  2. Homenaje al Profesor Académico Juan Di Doménico.

    Directory of Open Access Journals (Sweden)

    Roberto Vergara Támara

    2004-03-01


    Nápoles en 1924 donde completó su bachillerato Académico en el Liceo Umberto 1. Estudió medicina desde 1931 y se graduó en 1937. En 1938 aprobó los exámenes estatales para ejercer la medicina en Italia.

    Casado con Carmen Buraglia Stella (1947-1992. Sus hijos: Juan Francisco, Cirujano y Claudio Maurizio, Arquitecto, constructor. Sus nietos: Stefano, Eric, Claudia y Valeria.
    Viajó a Estados Unidos, se especializó en Cirugía General. Internado Rotatorio en el Merey Hospital Davenport, lowa, 1939-1940. Se matriculó en un Curso de Cirugía General en el Cook County Graduate School of Medicine, 1939-1941 Yen la Mayo Clinic de Rochester, Minnesota. Asistió además al Columbus Hospital de New York y al Charity Hospital de New Orleans...


  3. РЕКОМЕНДАЦИИ ПО РЕВАСКУЛЯРИЗАЦИИ МИОКАРДА

    Directory of Open Access Journals (Sweden)

    2011-01-01

    Full Text Available Комитет ESC по практическим рекомендациям: Alec Vahanian (председатель (Франция, Angelo Auricchio (Швейцария, Jeroen Bax (Нидерланды, Claudio Ceconi (Италия, Veronica Dean (Франция, Gerasimos Filippatos (Греция, Christian Funck-Brentano (Франция, Richard Hobbs (Великобритания, Peter Kearney (Ирландия, Theresa McDonagh (Великобритания, Bogdan A. Popescu (Румыния, Zeljko Reiner (Хорватия, Udo Sechtem (Германия, Per Anton Sirnes (Норвегия, Michal Tendera (польша, Panos E. Vardas (Греция, Petr Widimsky (Чешская республикаКомитет EACTS по клиническим рекомендациям: Philippe Kolh (председатель (Бельгия, Ottavio Alfieri (Италия, Joel Dunning (Великобритания, Stefano Elia (Италия, Pieter Kappetein (Нидпрланды, Ulf Lockowandt (Швеция, George Sarris (Греция, Pascal Vouhe (ФранцияРецензенты: Peter Kearney (координатор от Комитета ЕОК по практическим рекомендациям (Ирландия, Ludwig von Segesser (координатор от EACTS (Швейцария, Stefan Agewall (Норвегия, Alexander Aladashvili (Грузия, Dimitrios Alexopoulos (Греция, Manuel J. Antunes (Португалия, Enver Atalar (Тур-ция, Aart Brutel de la Riviere (Нидерланды, Alexander Doganov (Болгария, Jaan Eha (Эстония, Jean Fajadet (Франция, Rafael Ferreira (Португалия, Jerome Garot (Франция, Julian Halcox (Великобритания, Yonathan Hasin (Израиль, Stefan Janssens (Бельгия, Kari Kervinen (Финляндия, Gunther Laufer (Австрия, Victor Legrand (Бельгия, Samer A.M. Nashef (Великобритания, Franz

  4. PREFACE: XIV International Conference on Calorimetry in High Energy Physics

    Science.gov (United States)

    Wang, Yifang

    2011-03-01

    (Texas Tech University), Weidong Li (IHEP) 3) Readout techniques - Gerald Eigen (University of Bergen), Zheng Wang (IHEP) 4) Operating calorimeters and calibration - Marat Gataullin (CERN), Francesco Lanni (BNL) 5) Future calorimetry - Tohru Takeshita (Shinshu University), Lei Xia (Argonne National Laboratory) 6) Astrophysics and neutrino calorimetry - Giuliana Fiorillo (INFN), Hiro Tajima (SLAC) List of Participants AKCHURIN, NuralTexas Tech University AN, ZhenghuaIHEP AUFFRAY, EtiennetteCERN BANFI, DaniloUniversità degli Studi di Milano, INFN BASHARINA-FRESHVILLE, AnastasiaUniversity College London BEAUCHEMIN, Pierre-HuguesUniversity of Oxford BENAGLIA, Andrea DavideUniversity of Milano - Bicocca and INFN BIAN, JianminIHEP BIINO, CristinaINFN BILKI, BurakUniversity of Iowa BLAHA, JanLAPP BOUDRY, VincentLLR / CNRS-IN2P3 CAI, XiaoIHEP CAPONE, AntonioPhysics Department University "La Sapienza" and INFN CAVALLARI, FrancescaCERN and INFN Rome CECCHI, ClaudiaUniversity di Perugia e INFN CHANG, JinfanIHEP CHEN, HuchengBrookhaven National Laboratory CHILDERS, TaylorUniversität Heidelberg - Kirchhoff-Institut für Physik DAO, ValerioGeneva University - DPNC DE LA TAILLE, ChristopheIN2P3/OMEGA-LAL DIEMOZ, MarcellaINFN Roma DOTTI, AndreaCERN EIGEN, GeraldUniversity of Bergen EPIFANOV, DenisBudker Institute of Nuclear Physics FAIVRE, JulienLPSC Grenoble France FANG, JianIHEP FANG, ShuangshiIHEP FANTONI, AlessandraINFN - LNF FERRI, FedericoCEA/Saclay Irfu/SPP FERRONI, FernandoSapienza University & INFN Roma FISK, Henry EugeneFermilab GABALDON, CarolinaCERN GARUTTI, ErikaDESY GAUDIO, GabriellaIstituto Nazionale di Fisica Nucleare - Sezione di Pavia GILLBERG, DagCarleton University GIOVANNINI, PaolaMax-Planck-Institut für Physik GLAZOV, AlexanderDESY GRACHOV, OlegUniversity of Kansas HAPPACHER, FabioINFN HE, MiaoIHEP HORI, YasutoUniversity of Tokyo, CNS HU, TaoIHEP HULTH, Per-OlofStockholm University JUN, Soon YungCarnegie Mellon University JURK, StefanISEG Spezialelektronik gmb

  5. Editorial

    Directory of Open Access Journals (Sweden)

    Silmara Cimbalista

    2008-01-01

    Full Text Available EDITORIAL   Com temas diversos, unidos por uma perspectiva interdisciplinar comum, apresentamos mais um número da nossa revista eletrônica, relativa ao segundo semestre de 2008. Inicialmente temos um instigante artigo de Fabio di Clemente, Doutor em Filosofia pela Universidade de Urbino (Itália, na qual foi docente de História da Tradição dos Povos e diretor didático do Mestrado em História do Pensamento Filosófico, Político e Pedagógico. O texto procura investigar, sobretudo através da obra de Merleau-Ponty, o significado de uma possível recuperação das noções de fundamento e de subjetividade. Frente às autocríticas, às crises e ao desejo de superação que tais noções produziram em si mesmas através da história, o autor procura aqui requalificá-las tanto em relação à tradição filosófica quanto em relação à reflexão sobre a ciência como tal, defendendo uma superação de um quadro metodológico dualista e reducionista. Nessa perspectiva, a noção de subjetividade, situada dentro da corporeidade e dentro do “plano de ser”, pode ser redescoberta na sua “vocação ontológica”, para além de toda equivocidade. O texto busca, em síntese, apresentar-se como uma releitura das relações entre a filosofia e a ciência a partir do conceito de corpo. A seguir, Antônio Macena Figueiredo, Doutorando do Programa de Pós-Graduação em Ciências da Saúde (UnB/DF, Volnei Garrafa, Doutor em Ciências pela UNESP, orientador do Programa de Pós-Graduação em Ciências da Saúde, Coordenador da Cátedra UNESCO de Bioética da UnB, Coordenador do Programa de Pós-Gradação em Bioética da UnB, e Jorge Alberto Cordón Portillo, Doutor em Ciências da Saúde pela UnB, discutem o ensino da bioética na área das Ciências da Saúde no Brasil. Com base em um estudo exploratório e descritivo, e com dados levantados junto a periódicos científicos e dissertações e teses, o resultado da pesquisa mostrou existirem

  6. Libro de un Médico del Siglo XVI

    Directory of Open Access Journals (Sweden)

    Fernando Serpa Florez

    1986-12-01

    ía esperar un médico de cabecera de quien, como informaba otro embajador, “era cruel y cambiante, gozaba viendo cómo asaban vivas las liebres después de una cacería, y una vez que una tortuga le mordió un dedo, le destrozó la cabeza a mordiscos” En buena hora -y no sabemos cómo—logra salvar estas acechanzas. (“Fabio las ambiciones cortesanas prisiones son do el incauto cae”. Y prefiere alejarse de intrigas, grandes de España y archiduques locos, poniendo de por medio la mayor distancia posible. Irse, en fin, a las Indias, para lo cual pide -y obtiene– el salvoconducto respectivo...

  7. List of Participants

    Science.gov (United States)

    2007-11-01

    Mohab Abou ZeidVrije Universiteit, Brussel Joke AdamKatholieke Universiteit Leuven Nikolas AkerblomMax-Planck-Institut für Physik, München Luis Fernando Alday Utrecht University Stelios Alexandris University of Patras Antonio Amariti Università di Milano-Bicocca Nicola Ambrosetti Université de Neuchâtel Pascal Anastasopoulos Università di Roma Tor Vergata Laura Andrianopoli Enrico Fermi Center Carlo Angelantonj Università di Torino Lilia Anguelova Queen Mary, University of London Daniel AreanUniversidade de Santiago de Compostela Gleb ArutyunovUtrecht University Spyros Avramis NTU Athens—University of Patras Ioannis Bakas University of Patras Subrata Bal Dublin Institute for Advanced Studies Igor Bandos Valencia University Jessica Barrett University of Iceland Marco Baumgartl Eidgenössische Technische Hochschule, Zürich Jacopo Bechi Università di Firenze James Bedford Queen Mary, University of London Jorge Bellorin Universidad Autonoma de Madrid Francesco Benini SISSA, Trieste Eric Bergshoeff Centre for Theoretical Physics, University of Groningen Gaetano BertoldiUniversity of Wales, Swansea Adel Bilal Laboratoire de Physique Théorique, École Normale Superieure, Paris Matthias Blau Université de Neuchâtel Johannes BroedelUniversität Hannover Felix Brümmer Universität Heidelberg Julio Cesar Bueno de Andrade São Paulo State University—UNESP Cliff Burgess McMaster University Agostino Butti Laboratoire de Physique Théorique, École Normale Superieure, Paris Marco Caldarelli Universitat de Barcelona Pablo G Camara Centre de Physique Théorique, École Polytechnique, Palaiseau Joan Camps Universitat de Barcelona Felipe Canoura FernandezUniversidade de Santiago de Compostela Luigi Cappiello Università di Napoli Federico II Luca Carlevaro École Polytechnique, Palaiseau Roberto Casero Centre de Physique Théorique, École Polytechnique, Palaiseau Claudio Caviezel Max-Planck-Institut für Physik, München Alessio Celi Universitat de Barcelona Anna

  8. Editorial

    Directory of Open Access Journals (Sweden)

    Clarice Helena de Miranda Coimbra

    2015-01-01

    de Janeiro, campus Paracambi. O segundo artigo intitulado “Um breve panorama sobre o léxico em linguística cognitiva”, é de autoria de Caio Cesar Castro da Silva, que apresenta uma introdução aos estudos lexicais de base cognitiva. O terceiro artigo intitulado “Estudo teórico do sufixo nominalizador –ura: como descrevê-lo?” é de autoria de Ana Carolina Mrad de Moura Valente, que levou em consideração os diversos estudos em língua portuguesa sobre nominalização e apresentou em seu artigo, um levantamento dos estudos sobre o sufixo –ura em português. O quarto artigo de autoria de Nilton Rodrigues Junior, intitula-se “Pastoras na voz, insubmissas na vida? As mulheres da velha guarda da Portela”, o qual procurou interpretar as relações de gênero entre os integrantes do grupo partindo do entendimento do lugar social das pastoras. O quinto artigo é de autoria de Claudio Alberto Mendes Gomes que tem como título “A importância do conceito de razão na perspectiva de Pascal em breve comparação com o pensamento cartesiano”, procurando o autor demonstrar teoricamente como se construiu o conceito de razão pascalino difundido nos séculos XVI e XVII. Apresentamos o sexto artigo de autoria de Bruno dos Santos Silva, intitulado “O conceito de psicopatia analisado pela criminologia crítica”. Em seu artigo o autor investiga o conceito de psicopatia, ainda no século XIX até os dias atuais, utilizando construções da Criminologia para interpretar a conformação do objeto psicopatia e que repercussões institucionais ela pode trazer. O sétimo artigo “A água como bem jurídico econômico”, é de autoria de Natacha Zanghelini Borba e de Diego Augusto Bayer; aqui, seus autores procuraram apresentar as principais mudanças das leis para a cobrança da água, bem como demonstrar a escassez desse recurso no mundo e no Brasil. No oitavo artigo, Thamyrys Baur Tuffi Alli, apresenta como título “Responsabilização criminal da pessoa

  9. An Analysis of Administrative Corruption (Administrative Organizations of Yazd City

    Directory of Open Access Journals (Sweden)

    Mansour Haghighatian

    2013-02-01

    Matter, social science research network.   Ritzer, George.(2011. Sociological Theory. Eighth edition. New York: mc graw Hill   Rabie, Ali. (2004. Long Live Corruption: Political sociology of Corruption in the Third World Governments. The Ministry of Islamic culture and Guidance   Rafipoor, Faramarz. (1997. Modernization and Conflict: An attempt toward the analysis of the Islamic Revolution and Social Problems o Iran. Tehran: shahid Beheshti University   Robbins, Stephen p. (1991. Organizational Behavior: concepts Controversies, and Applications. Fourth edition, new jersey: prentice-Hall, Inc   Sabatini , Fabio. (2005.”Dose social capital Improve Labor productivity in small and Medium Enterprises/” from : www.socialcapitalgetewat.org (sabatin:2005a   Scott, Richard W.(1992. Organization: rational, natural, and open systems, third edition. New Jersey: prentice-Hall   .Shanon, A. R. (2003. The relationship between organized recreational programs and job satisfaction,” The University Connecticut   Singer, Marc J. (1999. Human Resources Management. Translated by Farideh Ale-agha. Tehran: the Center for Public administration Training   Steers, R.M. (1987. An introduction to organizational behavior". 3 rd ed. scot forsmand and company .   Tresiman, Daniel. 2000. The causes of corruption: a cross-national study, Journal of Public Economics, 76 pp 399 – 457.   www.Ostan yazd.ir   

  10. Programa de Pós-Graduação em Geologia - Dissertações Defendidas 1999 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    1999-01-01

    é então conhecidas. Os taxa identificados são concordantes com a idéia vigente de que as condições climáticas, ambientais e ecológicas eram diferentes dos atualmente reinantes no nordeste brasileiro durante o Pleistoceno final sub-recente, quando prevalecia um ambiente semi-árido mais ameno. Nome: Francisco Crescêncio Júnior Orientador: Claudio Gerhiem Porto Título: Estudomorfológico e Químico dos Grãos de Ouro do Minério Oxidado da Mina de Roça Grande Ii, Mg Resumo: A partir do final da década de 70 e nos anos 80, graças ao aumento do preço do ouro, intensificaram-se as pesquisas relacionadas ao comportamento deste metal em ambientes supergênicos. Várias pesquisas se desenvolveram na Austrália, África e Brasil, voltadas, principalmente, para os depósitos supergênicos lateríticos, onde se verificou que o ouro pode sofrer remobilização, através de processos químicos e físicos. A área do presente estudo, Mina de Roça Grande II, situa-se no Quadrilátero Ferrífero, MG. O depósito encaixa-se nos metassedimentos químicos do Grupo Nova Lima. Tanto o estudo da morfologia dos grãos de ouro com auxílio de lupa binocular e microscópio eletrônico de varredura (MEV acoplado a um analisador de imagem quanto da composição química destes grãos com auxílio da microssonda eletrônica, visou elucidar a atuação de tais processos. Na zona oxidada da mina foram estudados os níveis de saprock e saprolito na formação ferrífera e no metachert, além de um nível de solo coluvionar. Estes horizontes caracterizam um perfil intempérico típico de regiões de altitudes elevadas e de natureza supergênica não-laterítica. O estudo da morfologia dos grãos de ouro revelou que os grãos do solo tendem a ser mais regulares, lisos e arredondados, demonstrando maior desgaste em relação aos grãos encontrados nos outros horizontes. O analisador de imagem, apesar de diferenciar grãos regulares e irregulares, confirmando as observações de lupa

  11. 6th International Symposium on Molecular Allergology (ISMA

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    Christiane Hilger

    2016-10-01

    Full Text Available Table of contents ORAL ABSTRACTS Symposium 1: Biochemistry, structure and environment of the allergen: what makes a protein an allergen? O1 Two cell-membrane peptidases carrying galactose-alpha-1,3-galactose are implicated in delayed anaphylactic reactions upon pork kidney ingestion in patients with IgE-antibodies to alpha-Gal Christiane Hilger, Kyra Swiontek, Jörg Fischer, François Hentges, Christiane Lehners, Martine Morisset, Bernadette Eberlein, Tilo Biedermann, Markus Ollert O2 Structure solution of Pla l 1 suggests similar folding of Ole e 1-like family members but distinct immunological properties Sabrina Wildner, Teresa Stemeseder, Regina Freier, Peter Briza, Roland Lang, Eva Batanero, Mayte Villalba, Jonas Lidholm, Thomas Hawranek, Fatima Ferreira, Hans Brandstetter, Gabriele Gadermaier Symposium 2: New allergen molecules in the spotlight O3 Identification of the cysteine protease Amb a 11 as a novel major allergen from short ragweed (Ambrosia artemisiifolia Philippe Moingeon, Rachel Groeme, Julien Bouley, Véronique Bordas, Maxime Le Mignon, Laetitia Bussières, Aurélie Lautrette, Laurent Mascarell, Vincent Lombardi, Véronique Baron-Bodo, Henri Chabre, Thierry Batard, Emmanuel Nony O4 Production and characterization of polybia paulista recombinant antigen 5: a valuable diagnostic tool Karine Marafigo De Amicis, Alexandra Sayuri Watanabe, Daniele Danella Figo, José Roberto Aparecido Dos Santos-Pinto, Mario Sergio Palma, Fabio Fernandes Morato Castro, Jorge Kalil, Therese Wohlschlager, Peter Briza, Sabrina Wildner, Fatima Ferreira-Briza, Gabriele Gadermaier, Keity Souza Santos Symposium 3: Progress in molecular and cellular diagnosis O5 Basophil activation test with recombinant Pru p 3; identifying genuine peach allergic patients Margaretha Faber, Athina Van Gasse, Vito Sabato, Margo M. Hagendorens, Chris H. Bridts, Luc S. De Clerck, Araceli Diaz Perales, Didier Ebo O6 Nanofluidic technology enables rapid, near

  12. PREFACE: Fourth Meeting on Constrained Dynamics and Quantum Gravity

    Science.gov (United States)

    Cadoni, Mariano; Cavaglia, Marco; Nelson, Jeanette E.

    2006-04-01

    ) Georgi Dvali (NYU, USA) Sergio Ferrara (CERN) Gian Francesco Giudice (CERN) Roman Jackiw (MIT, USA) Edward W. Kolb (Fermilab, USA) Luca Lusanna (INFN Firenze, Italy) Roy Maartens (Univ. Portsmouth, UK) Hermann Nicolai (AEI, Potsdam, Germany) Tullio Regge (Politecnico di Torino, Italy) Augusto Sagnotti (Univ. Roma Tor Vergata, Italy) Kellogg S. Stelle (Imperial College London, UK) Ruth Williams (DAMTP, Cambridge, UK) SPONSORS Istituto Nazionale di Fisica Nucleare Università di Cagliari Università di Torino University of Mississippi Università di Pisa Regione autonoma della Sardegna Tiscali LIST OF PARTICIPANTS Eun-Joo Ahn (University of Chicago, USA) David Alba (Università di Firenze, Italy) Stanislav Alexeyev (Lomonosov Moscow State U., Russia) Damiano Anselmi (Università di Pisa, Italy) Ignatios Antoniadis (CERN, Geneva, Switzerland) Maria Da Conceicao Bento (Instituto Superior Técnico, Lisboa, Portugal) Orfeu Bertolami (Instituto Superior Técnico, Lisboa, Portugal) Massimo Bianchi (Università di Roma Tor Vergata, Italy) Mariam Bouhmadi-Lopez (University of Portsmouth, UK) Raphael Bousso (University of California at Berkeley, USA) Mariano Cadoni (Università di Cagliari, Italy) Steven Carlip (University of California at Davis, USA) Roberto Casadio (Università di Bologna, Italy) Marco Cavaglià (University of Mississippi, USA) Demian Cho (Raman Research Institute, Bangalore, India) Theodosios Christodoulakis (University of Athens, Greece) Chryssomalis Chryssomalakos (Inst. de Ciencias Nucleares - UNAM, Mexico) Diego Julio Cirilo-Lombardo (JINR, Dubna, Russia) Denis Comelli INFN, Sezione di Ferrara, Italy ) Ruben Cordero-Elizalde (Instituto Politecnico Nacional, Mexico) Lorenzo Cornalba (Università di Roma Tor Vergata, Italy) Branislav Cvetkovic (Institute of Physics, Belgrade, Serbia ) Maro Cvitan (University of Zagreb, Croatia) Alessandro D'Adda (Università di Torino, Italy) Claudio Dappiaggi (Università di Pavia, Italy) Roberto De Leo (Università di

  13. Programa de Pós Graduação em Ciências Atmosféricas em Engenharia - 2005 -Teses Defendidas - Doutorado - Instituto de Geociências - UFRJ

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    2005-01-01

    campo. As metodologias para a estimativa da TST são apresentadas e seus resultados discutidos. Os melhores resultados foram obtidos pelas metodologias de França (1994 e de Bastiaanssen (1995 que apresentaram erros médios de estimativa iguais a 0,2oC e 0,6oC, respectivamente. Autor: Audalio Rebelo Torres Junior Orientadores: Claudio Freitas Neves (COPPE e Affonso da Silveira Mascarenhas Junior Título: Estudo numérico sobre tele-conexão atmosférica entre fenômenos oceânicos do Pacífico Equatorial e do Atlântico Sul No de páginas: 147 Resumo Neste trabalho é demonstrado como, nas escalas sazonal e interanual, a Alta Subtropical do Atlântico Sul em resposta às anomalias de temperatura da superfície do mar no Pacífico equatorial e via circulação de Walker e Hadley, influencia a profundidade e conseqüentemente a disponibilidade da Água Central do Atlântico Sul ao bombeamento de Ekman, na bacia sudoeste do Atlântico Sul. Foram utilizados dados das reanálises do National Center for Environmental Prediction e do experimento de assimilação de dados do Geophysical Fluid Dynamics Laboratory, bem como realizadas simulações da atmosfera em escala global, aplicando o Community Climate Model do National Center for Atmopheric Research e, simulações oceânicas em escala de bacia com o Princeton Ocean Model. Os resultados dos modelos mostraram alterações no padrão de circulação das células de Hadley e Walker, implicando no comportamento da Alta Subtropical do Atlântico. O Oceano respondeu com aumento do transporte da Corrente do Brasil e intensificação da corrente das Malvinas. A ACAS ficou mais rasa respondendo à variação do balanço de Sverdrup. Autor: Gevaldo Lisboa de Almeida Orientadores: Renato Machado Cotta e Luiz Cláudio Gomes Pimentel Título: Análise da dispersão de poluentes na atmosfera usando a técnica da transformada integral generalizada No de páginas: 165 215 Programa de Pós Graduação em Ciências Atmosféricas em

  14. Programa de Pós-Graduação em Geologia - Dissertações Defendidas 2001 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    2001-01-01

    Full Text Available 40 Anuário do Instituto de Geociências - UFRJ Volume 24 / 2001 Programa de Pós-Graduação em Geologia Dissertações Defendidas - Mestrado Nome: Aline Theophilo Silva Orientadores: Claudio Limeira Mello, Cláudio Coelho de Lima e Hélio Maurício Ribeiro dos Santos Título: Um estudo da influência do estado de tensões in-situ sobre a estabilidade de poços Resumo: O conhecimento do estado de tensões in-situ é um fator fundamental para diversas atividades da explotação na indústria do petróleo. Tal conhecimento gera subsídios para projetos de poços direcionais e de fraturamento hidráulico, previsão de produção de areia e de várias outras atividades. Com base na premissa de que as bacias da margem atlântica brasileira são tectonicamente relaxadas, o planejamento de atividades de explotação no Brasil é usualmente feito assumindo-se que as tensões horizontais principais são iguais e dependem somente da tensão de sobrecarga. Entretanto, compilações do estado de tensões em escala mundial, feitas no contexto do WORLD STRESS MAP (Zoback, 1992, indicam que esta premissa pode não ser correta, visto que a tensão principal máxima é horizontal em muitas partes do mundo. No Brasil, trabalhos baseados em sismologia e na análise da magnitude de tensões obtidas a partir de fraturamentos hidráulicos e de testes de leak-off disponíveis em várias bacias têm mostrado que usualmente a maior das tensões principais é horizontal. Nesta tese, fezse um estudo do estado de tensões in-situ num campo de petróleo utilizando-se: análise de breakouts, para a determinação da orientação das tensões horizontais in-situ; testes de leak-off obtidos de poços verticais e testes de leak-off obtidos de poços direcionais (usados na inversão de leak-off, para estimar-se as magnitudes das tensões horizontais in-situ. O tensor de tensões calculado pela inversão de leak-off reproduziu a orientação das tensões horizontais obtida atrav

  15. Programa de Pós-Graduação em Geologia - Teses Defendidas 2000 - Doutorado - Instituto de Geociências - UFRJ

    Directory of Open Access Journals (Sweden)

    2000-01-01

    braquiúres foi soterrada após sua morte (posição normal, embora 25% deles represente indivíduos que foram surpreendidos pelo soterramento (posição de escape. A maioria dos cadáveres com o tórax intacto indica que os processos de decomposição foram interrompidos com a formação das concreções. Foram individualizadas quatro morfologias nos carcinólitos, a saber: prolatos, arredondados, bifurcados e cintados. Nos dois primeiros tipos ocorrem apenas um indivíduo em seu interior, enquanto que nos demais são encontradas partes morfológicas de indivíduos diferentes. A espessura da concreção é função direta da duração dos processos de decomposição. As feições diagenéticas sugerem que os carcinólitos se formaram segundo a seguinte seqüência de etapas: dissolução, recristalização, fosfatização, silicificação e compressão. Em algumas concreções os braquiúres estão expostos em sua superfície. Esta feição representa ação erosiva por transporte fluvial ou ação de marés, que causou abrasão e corrosão dos carcinólitos, sendo considerada portanto, uma feição pós-diagenética. A presença de microfósseis marinhos, e de formas jovens e adultas, algumas desarticuladas e fragmentadas, de braquiúres na paleotafocenose, sugerem um evento de mortandade em massa. A ausência de dados faciológicos das rochas encaixantes dos carcinólitos, torna difícil inferir as causas desse evento catastrófico. Entretanto, pode-se sugerir que ondas de tempestade podem ter provocado remoção do fundo lamoso rico em H2S, e causado a morte dos organismos por envenenamen- 36 Anuário do Instituto de Geociências - UFRJ Volume 23 / 2000 to. A posição de soterramento de alguns exemplares de Uca maracoani pode refletir a ação de correntes de lama, que causou soterramento destes, antes de sua morte. Nome: Miguel Armony Orientador: Claudio Bettini Título: Geoestatística paramétrica de campo Resumo: Muitas técnicas foram introduzidas ao longo do

  16. EDITORIAL: Colloidal dispersions in external fields Colloidal dispersions in external fields

    Science.gov (United States)

    Löwen, Hartmut

    2012-11-01

    , Ojeda-Lopez M A and Arauz-Lara J L 2012 J. Phys. Condens. Matter 24 464126 [31]Leferink op Reinink A B G M, van den Pol E, Byelov D V, Petukhov A V and Vroege G J 2012 J. Phys. Condens. Matter 24 464127 [32]Taylor S L, Evans R and Royall C P 2012 J. Phys. Condens. Matter 24 464128 [33]Toner J, Tu Y H and Ramaswamy S 2012 J. Phys. Condens. Matter 24 464110 [34]Schmitz R and Dünweg B 2005 J. Phys. Condens. Matter 318 170 [35]Cates M E 2012 Rep. Prog. Phys. 75 042601 [36]Tarama M and Ohta T 2012 J. Phys. Condens. Matter 24 464129 [37]Wensink H H and Löwen H 2012 J. Phys. Condens. Matter 24 464130 Colloidal dispersions in external fields contents Colloidal dispersions in external fieldsHartmut Löwen Depletion induced clustering in mixtures of colloidal spheres and fd-virusD Guu, J K G Dhont, G A Vliegenthart and M P Lettinga Advanced rheological characterization of soft colloidal model systemsS Gupta, S K Kundu, J Stellbrink, L Willner, J Allgaier and D Richter Conformational and dynamical properties of ultra-soft colloids in semi-dilute solutions under shear flowSunil P Singh, Dmitry A Fedosov, Apratim Chatterji, Roland G Winkler and Gerhard Gompper Transient dynamics in dense colloidal suspensions under shear: shear rate dependenceM Laurati, K J Mutch, N Koumakis, J Zausch, C P Amann, A B Schofield, G Petekidis, J F Brady, J Horbach, M Fuchs and S U Egelhaaf Force-induced diffusion in microrheologyCh J Harrer, D Winter, J Horbach, M Fuchs and Th Voigtmann Micro-macro-discrepancies in nonlinear microrheology: I. Quantifying mechanisms in a suspension of Brownian ellipsoidsRyan J DePuit and Todd M Squires Micro-macro discrepancies in nonlinear microrheology: II. Effect of probe shapeRyan J DePuit and Todd M Squires Viscosity of electrolyte solutions: a mode-coupling theoryClaudio Contreras-Aburto and Gerhard Nägele Electro-kinetics of charged-sphere suspensions explored by integral low-angle super-heterodyne laser Doppler velocimetryThomas Palberg, Tetyana K

  17. List of Participants

    Science.gov (United States)

    2008-11-01

    Davide CassaniLaboratoire de Physique Théorique, École Normale Supérieure, Paris Alejandra CastroUniversity of Michigan Claudio Caviezel Max-Planck-Institut für Physik, München Alessio Celi Universitat de Barcelona Anna Ceresole Istituto Nazionale di Fisica Nucleare, Università di Torino Athanasios ChatzistavrakidisNational Technical University of Athens Wissam ChemissanyCentre for Theoretical Physics, University of Groningen Eugen-Mihaita CioroianuUniversity of Craiova Andres CollinucciTechnische Universität Wien Paul CookUniversità di Roma, Tor Vergata Lorenzo CornalbaUniversità di Milano-Bicocca Aldo CotroneKatholieke Universiteit Leuven Ben Craps Vrije Universiteit, Brussel Stefano Cremonesi SISSA, Trieste Riccardo D'AuriaPolitecnico di Torino Gianguido Dall'AgataUniversity of Padova Jose A de AzcarragaUniversidad de Valencia Jan de BoerInstituut voor Theoretische Fysica, Universiteit van Amsterdam Sophie de BuylInstitut des Hautes Études Scientifiques, Bures-sur-Yvette Marius de LeeuwUtrecht University Frederik De RooVrije Universiteit, Brussel Jan De Rydt Katholieke Universiteit Leuven and CERN, Geneva Bernard de WitInstitute for Theoretical Physics, Utrecht University Stephane DetournayIstituto Nazionale di Fisica Nucleare, Sezione di Milano Paolo Di Vecchia Niels Bohr Institute, København Eugen DiaconuUniversity of Craiova Vladimir Dobrev Institute for Nuclear Research and Nuclear Energy, Bulgarian Academy of Sciences, Sofia Nick DoreyUniversity of Cambridge Hajar Ebrahim NajafabadiIPM, Tehran Federico Elmetti Università di Milano Oleg Evnin Vrije Universiteit, Brussel Francesco Fiamberti Università di Milano Davide Forcella SISSA, Trieste and CERN, Geneva Valentina Forini Humboldt-Universität zu Berlin Angelos Fotopoulos Università di Torino Denis Frank Université de Neuchâtel Marialuisa Frau Università di Torino Matthias Gaberdiel Eidgenössische Technische Hochschule (ETH), Zürich Diego Gallego SISSA/ISAS, Trieste Maria Pilar Garcia del

  18. Undercover Stars Among Exoplanet Candidates

    Science.gov (United States)

    2005-03-01

    is only 16% larger than this giant planet! A Dense Star "Imagine that you add 95 times its own mass to Jupiter and nevertheless end up with a star that is only slightly larger", suggests Claudio Melo from ESO and member of the team of astronomers who made the study. "The object just shrinks to make room for the additional matter, becoming more and more dense." The density of such a star is more than 50 times the density of the Sun. "This result shows the existence of stars that look strikingly like planets, even from close by", emphasizes Frederic Pont of the Geneva Observatory (Switzerland). "Isn't it strange to imagine that even if we were to receive images from a future space probe approaching such an object at close range, it wouldn't be easy to discern whether it is a star or a planet?" As all stars, OGLE-TR-122b produces indeed energy in its interior by means of nuclear reactions. However, because of its low mass, this internal energy production is very small, especially compared to the energy produced by its solar-like companion star. Not less striking is the fact that exoplanets which are orbiting very close to their host star, the so-called "hot Jupiters", have radii which may be larger than the newly found star. The radius of exoplanet HD209458b, for example, is about 30% larger than that of Jupiter. It is thus substantially larger than OGLE-TR-122b! Masqueraders ESO PR Photo 06c/05 ESO PR Photo 06c/05 Comparison Between OGLE-TR-122b, Jupiter and the Sun [Preview - JPEG: 400 x 598 pix - 30k] [Normal - JPEG: 800 x 1196 pix - 350k] [HiRes - JPEG: 5000 x 3344 pix - 2.2M] Caption: ESO PR Photo 06c/05 is a comparison between the newly found low-mass star OGLE-TR-122b and the Sun and Jupiter. OGLE-TR-122b, while still 96 times as massive as Jupiter, is only 16% larger than this giant planet. It weighs 1/11th the mass of the Sun and has 1/8th of its diameter. (credits: Sun image: SOHO/ESA; Jupiter: Cassini/NASA/JPL/University of Arizona/ESA) This discovery also

  19. A Portrait of One Hundred Thousand and One Galaxies

    Science.gov (United States)

    2002-08-01

    new and very accurate distance to NGC 300, making this galaxy a future cornerstone in the calibration of the cosmic distance scale . Moreover, they will also allow to understand in more detail how the brightness of a Cepheid-type star depends on its chemical composition, currently a major uncertainty in the application of the Cepheid method to the calibration of the extragalactic distance scale. Indeed, the effect of the abundance of different elements on the luminosity of a Cepheid can be especially well measured in NGC 300 due to the existence of large variations of these abundances in the stars located in the disk of this galaxy. Gieren and his group, in collaboration with astronomers Fabio Bresolin and Rolf Kudritzki (Institute of Astronomy, Hawaii, USA) are currently measuring the variations of these chemical abundances in stars in the disk of NGC 300, by means of spectra of about 60 blue supergiant stars, obtained with the FORS multi-mode instruments at the ESO Very Large Telescope (VLT) on Paranal. These stars, that are among the optically brightest in NGC 300, were first identified in the WFI images of this galaxy obtained in different colours - the same that were used to produce PR Photo 18a/02 . The nature of those stars was later spectroscopically confirmed at the VLT. As an important byproduct of these measurements, the luminosities of the blue supergiant stars in NGC 300 will themselves be calibrated (as a new cosmic "standard candle"), taking advantage of their stellar wind properties that can be measured from the VLT spectra. The WFI Cepheid observations in NGC 300, as well as the VLT blue supergiant star observations, form part of a large research project recently initiated by Gieren and his group that is concerned with the improvement of various stellar distance indicators in nearby galaxies (the "ARAUCARIA" project ). Clues on star formation history in NGC 300 ESO PR Photo 18c/02 ESO PR Photo 18c/02 [Preview - JPEG: 440 x 400 pix - 63k] [Normal

  20. Programa de Pós-Graduação em Geografia - Dissertações Defendidas 2000 - Mestrado - Instituto de Geociências - UFRJ

    Directory of Open Access Journals (Sweden)

    2000-01-01

    frontais. Nesse contexto, o estudo teve por objetivo geral caracterizar o balanço sedimentar em um trecho do cordão de dunas frontais adjacentes à praia de Massambaba. a metodologia desenvolvida teve por base o monitoramento do campo de dunas frontais durante 22 meses (09.03.1996 a 31.12.1997 onde foram empregadas técnicas de levantamento topográfico, coleta de areia em armadilhas e análise sedimentológica, que associadas ao comportamento climatológico do período, permitiram definir um comportamento sedimentar para as dunas frontais. Nome: Analia Margarita Romanello Orientador: Claudio Antonio Gonçalves Egler Título: Aplicação de sistema de informações geográficas (SIG na avaliação da qualidade de vida 42 Anuário do Instituto de Geociências - UFRJ Volume 23 / 2000 Resumo: Na última década, a tecnologia dos Sistemas de Informação Geográfica (SIGs ganhou prestígio como ferramenta moderna para o manejo da informação espacial aplicável aos estudos do território. As propriedades que caracterizam os SIGs podem contribuir para alcançar novos conhecimentos através da análise de dados e informação sobre o território, quer dizer, sobre a organização e o funcionamento do espaço geográfico. Sem dúvida, a complexidade que estes processos apresentam e as dificuldades ou inconveniências que acarreta o emprego de técnicas computacionais, colocam o debate acerca de sua correta aplicação e das limitações que surgem na implementação da tecnologia dos SIGs como contribuição aos estudos territoriais. O emprego de técnicas de geoprocessamento como ferramenta de avaliação, no entanto é ainda limitado, sobretudo se comparamos com sua potencialidade. Este fato se deve tanto a falta de domínio dos métodos destas ferramentas, como também às dificuldades de obtenção de dados confiáveis para uso em SIG. Assim, em cada novo avanço, a tecnologia oferece maiores possibilidades para atingir e usar o conhecimento sobre o território e para faz

  1. Programa de Pós-Graduação em Geografia - Teses Defendidas 2001- Doutorado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

    Directory of Open Access Journals (Sweden)

    2001-01-01

    Full Text Available 35 Anuário do Instituto de Geociências - UFRJ Volume 24 / 2001 Nome: Cesar Ajara Orientador: Bertha K. Becker Título: Brasil: Espaços incluídos e espaços excluídos na dinâmica da geração de riqueza. Resumo: Esta tese analisa o impacto das forças globalizadoras na reelaboração do espaço geográfico nacional, no período 1980-1996, procurando identificar a existência de uma nova configuração espacial atrelada à dinâmica econômico-espacial do país. Nesse sentido, associa a inclusão/exclusão de espaços mesorregionais à lógica da competitividade e seletividade espacial. Dentre os resultados alcançados, evidencia a emergência de operação de um movimento reconcentrador do crescimento econômico nos espaços hegemônicos da economia e a fragmentação do crescimento nas áreas periféricas a esses espaços. Identifica espaços incluídos, espaços excluídos e espaços de indefinição, como configuração espacial associada aos processos em curso no final do século XX. Conclui, destacando o quadro de acentuação de assimetrias quanto à capacidade mesorregional de produção, num país de dimensões continentais e marcado por grande heterogeneidade social, econômica e espacial. Visando a contribuir para a elaboração de conhecimento acerca da fase atual de reorganização do espaço nacional, o estudo identifica a existência de Brasis e indica uma agenda para pesquisas futuras neste campo de investigação. Nome: Marcelo Vinicius de La Rocha Domingues Orientador: Claudio Antonio Gonçalves Egler Título: Logística e transporte marítimo internacional: Impactos sobre o sistema Programa de Pós-Graduação em Geografia Teses Defendidas - Doutorado 36 Anuário do Instituto de Geociências - UFRJ Volume 24 / 2001 portuário brasileiro Resumo: A finalidade desta tese de doutorado é apresentar um modelo teórico interpretativo, à luz das novas teorias vigentes na Física, Química, Biologia e Matemática, sobre a rela

  2. Programa de Pós-Graduação em Geografia - Dissertações Defendidas 2002 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

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    2002-01-01

    mais parecem um “forno” do que um local de amenidade. Autor: Fabio Bonatto Orientador: Jorge Xavier da Silva Título: Transformações na paisagem natural de Boa Vista, Roraima: umdiagnóstico Ambiental por Geoprocessamento Resumo: O confronto entre a necessidade da informação geográfica e a escassez de dados orientados ao Planejamento Ambiental, em particular para a região amazônica, provocou a elaboração deste estudo, o qual parte da análise histórica do processo de ocupação 200 Anuário do Instituto de Geociências - UFRJ Volume 25 / 2002 humana da região, salientando a contribuição das expedições técnico-científicas, bem como dos estudos contemporâneos, que forneceram a base para o entendimento da evolução da paisagem regional e permitiram a construção do modelo conceitual da dinâmica de transformação da paisagem local. A reunião deste conjunto de dados e informações ancilares, onde a tecnologia do Sensoriamento Remoto possibilitou o registro espacial das diferentes feições de interesse ao trabalho, foi preconizada pela utilização da Metodologia de Geoprocessamento proposta por XAVIER-DA-SILVA (1999, a qual permitiu a organização e manipulação desta vasta massa de dados. Como produtos tem-se a criação de um Modelo Digital do Ambiente e, com a realização das Análises Ambientais, o diagnóstico das transformações da paisagem de Boa Vista, que conduziram à elaboração de um Modelo de Intervenção Ambiental voltado ao Planejamento da Ocupação Urbana e à Gestão dos Recursos Naturais de maneira integrada e indissociável. Autor: Paulo Roberto Russo Orientador: Ana Maria de Paiva Macedo Brandão Título: A Distribuição das Concentrações de Partículas em Suspensão na Atmosfera da Porção Centro-oriental do Município do Rio de Janeiro: Considerações Preliminares sobre s Correlação Saúde Pública e Poluição Atmosférica Resumo: A poluição atmosférica se apresenta neste início de século como um dos

  3. Apresentação - Introduction

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    RHE Asphe

    2015-05-01

    sociedade.Maria João de Carvalho, José Viegas Brás e Maria Neves Gonçalves, autores portugueses, elegem o conceito de self-government para compreender o contributo da obra de António Sérgio para a renovação da Educação na primeira metade do século 20 em Portugal. Uma gama variada de documentos indiciam as idéias deste importante autor: textos de conferências, cartas, textos doutrinários e ensaios. Destacam que no cerne do pensamento do autor encontra-se a concepção de educação baseada no self-government, ou seja, inspirado pela Escola Ativa, propugnava a criação de sujeitos livres, ativos, autónomos, emancipados, participando ativa e solidariamente numa escola-comunidade, regida pelos princípios do self-government.Somos convidados a acompanhar Felismina e Libertina à escola, ou em sua luta pelo acesso à educação na cidade do Rio de Janeiro, no período da abolição e no pós-abolição (1888-1906, discutido no artigo de Alessandra Frota Martinez de Schueler, Irma Rizzini e Jucinato Marques. Os autores se valem desse convite para examinar as tensões e limites da escolarização no contexto do pós-abolição, quando a instrução popular contrasta com expectativas e ações de libertos e livres. Entre outras ricas questões abordadas neste artigo, acerca de um período histórico pouco pesquisado, podemos estabelecer algumas relações com os artigos do dossiê deste número 46, pois os autores também constatam que o poder público valeu-se de malabarismos numéricos, apesar das fragilidades dos levantamentos estatísticos. Indicam que houve disputas para a produção e divulgação de estatísticas e ressaltam que os números podem ser lidos sob distintas perspectivas, por exemplo no que se refere aos índices de instrução pública da população e  às condições de acesso à instrução. O artigo seguinte, de Fabio de Faria Peres e Victor Andrade de Melo, detém-se no século 19, perscruta em três impressos em circulação no Rio de

  4. Programa de Pós-Graduação em Geologia - Dissertações Defendidas 1998 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

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    1998-01-01

    Full Text Available 106 Programa de Pós-Graduação em Geologia Dissertações Defendidas - Mestrado Nome: Cristiane Mendes Coelho Título: Análise Técnica-Econômica-Financeira de Projetos em Rochas Ornamentais no Município do Rio de Janeiro e Região Metropolitana - Estudos de Casos Orientador: Claudio Margueron Resumo: O processo de avaliação técnica-econômica-financeira de projetos em rochas ornamentais, envolve uma série de análises a serem consideradas. A descrição de alguns aspectos sobre a indústria em questão, com reservas e produção de rochas ornamentais, demanda de produtos, mercado interno e externo e programas de incentivo ao setor tentam situar as empresas em análise no seu contexto setorial. Uma descrição geral sobre o processo produtivo de rochas ornamentais, desde a extração de blocos em pedreiras até a fabricação de peças acabadas, mostra os principais métodos de extração e beneficiamento utilizados nessa indústria. Os estudos de casos serviram de base de dados para a avaliação técnicaeconômica- financeira de projetos a serem desenvolvidos no setor. A estrutura organizacional e infra-estrutura das empresas analisadas são descritas com enfoque para a linha de produção de beneficiamento primário (produção de chapas de granito. São destacados os aspectos técnicos de cada empresa durante o processo produtivo de chapas, como eficiência, desdobramento, velocidade de corte e consumo de insumos em cada caso. A implantação de tecnologia de serragem de blocos sugerida pelo SENAI-DN, surge como uma alternativa de diminuir os problemas detectados nas empresas em questão. São analisados em termos comparativos, os resultados obtidos com a aplicação desta nova tecnologia em relação a metodologia aplicada nas empresas. Devido a ausência de sistemas de custeio adequados para a medição dos resultados econômicos do processo de serragem, foi construído um sistema de custeio pleno com o objetivo de avaliar o custo

  5. Programa de Pós-Graduação em Geografia - Dissertações Defendidas 1999 - Mestrado - Instituto de Geociências - Universidade Federal do Rio de Janeiro

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    1999-01-01

    rio Paquequer (l35,18 km2, onde situa-se a cidade de Teresópolis-RJ. Avalia o comportamento da rede fluvial no processo de ocupação da cidade, ao longo de 41 anos (1956 a 1996, considerando o crescimento de áreas impermeáveis e os problemas na rede fluvial decorrentes dessa expansão. Analisa, em detalhe, a rede de drenagem da sub-bacia do rio Meudon (3ª. Ordem, exemplificadora das mudanças na geometria do canal e nas condições de drenagem. O trabalho foi dividido em 3 (três itens. A caracterização do ambiente da bacia, relevante para as mudanças das condições de drenagem, foi realizada através do inventário dos elementos que condicionam, direta e/ou indiretamente, a rede de drenagem (relevo, geologia, solo, clima, vegetação, ocupação e uso do solo. A seguir, foi avaliada rede de drenagem quanto às suas características morfológicas (hierarquia e morfometria quanto ao perfil longitudinal e aos valores de vazão. O terceiro tópico trata dos efeitos do crescimento urbano sobre os canais de terceira ordem, especialmente quanto as mudanças das condições da geometria dos canais na sub-bacia do rio Meudon. Foi avaliado o crescimento espacial da cidade através da comparação entre fotos aéreas de 1956, 1966, 1976 e imagem SPOT, de 1996. Os resultados mostraram que a dinâmica fluvial, na área urbana de Teresópolis, encontra-se bastante modificada, em especial, no que se relaciona à geometria dos canais e ao escoamento das águas, tendo em vista o crescimento da população e as modificações introduzidas. 130 Anuário do Instituto de Geociências - UFRJ Volume 22 / 1999 Nome: Pierre Alves Costa Orientador: Claudio Antonio Gonçalves Egler Título: A Geografia da Indústria de Química Fina da Região Metropolitana do Rio de Janeiro, Um Estudo de Caso: O Pólo de Química Fina de Jacarepaguá (RJ Resumo: A presente dissertação propõe-se a uma reflexão crítica sobre a Geografia da Indústria de Química Fina na Região Metropolitana do