Save our inboxes! Use e-mail wisely

CERN Multimedia

Achintya Rao

2013-01-01

At CERN, with collaborators all over the world, e-mail is inevitably the primary means of communication: we use it for everything from coordinating projects to organising lunches. But e-mail can also be one of the most inefficient means of communication we have! Here's how to fix it.   Let’s get straight to the point: we receive too many e-mails. Think about all the e-mails that you deleted without a second thought. Think about the times you’ve unnecessarily been in CC. Take a look at the unread e-mails sitting in your inbox at this very moment, ones that you have no intention of ever looking at. You can, however, tame this overload with a few simple measures and turn e-mail into an important communication and productivity tool. Many recommendations for improving e-mail etiquette suggest an abrasive approach riddled with bullet points. In a vastly multi-cultural setting such as CERN, however this approach may fail. So, here are a few dos and don’ts based o...

Visuelle Analyse von E-mail-Verkehr

OpenAIRE

Mansmann, Florian

2003-01-01

Diese Arbeit beschreibt Methoden zur visuellen geographischen Analyse von E-mail Verkehr.Aus dem Header einer E-mail können Hostadressen und IP-Adressen herausgefiltert werden. Anhand einer Datenbank werden diesen Host- und IP-Adressen geographische Koordinaten zugeordnet.Durch eine Visualisierung werden in übersichtlicher Art und Weise mehrere tausend E-mail Routen dargestellt. Zusätzlich dazu wurden interktive Manipulationsmöglichkeiten vorgestellt, welche eine visuelle Exploration der Date...

Compulsory registration of mail servers in order to accept e-mail from the Internet

CERN Multimedia

IT Department

2008-01-01

This announcement is intended only for administrators of a mail server (sendmail, postfix, etc.). It concerns e-mails sent from the Internet to addresses of the following type: somemailbox@somehost.cern.ch. Mail server managers are requested to register their servers so that they can accept e-mail from outside CERN. In future the CERN mail infrastructure will relay messages from outside CERN only to officially registered mail servers. This rule applies only to messages sent from the Internet. There will be NO change with respect to messages sent from inside CERN. If you are responsible for a mail server that accepts e-mails from outside CERN, please read the following page: http://cern.ch/mail/Help/?kbid=191090, where you can find information about the new rule and check if your host is already registered in the system. If you wish to register a mail server please send a message to: mailto:mail.support@cern.ch. This rule will be gradually enforced from 20 February 2008 onwards. Thank you for your cooperation...

Application for automatic e-mail forwarding

OpenAIRE

Skupek, Rok

2010-01-01

The diploma thesis has two main goals: the first objective is to develop a dynamic library, which will contain methods able to download e-mail messages from mail server using POP3 protocol. The second objective involves development of application for processing and distribution of e-mail messages. Introduction cointains presentation of a practical application example in real time situation. Here are described procedures used for development of server - client communication library, which u...

E-mail to SMS service change

CERN Multimedia

IT Department

2010-01-01

If you have a CERN e-mail account, you have probably already used one of the popular services that CERN’s IT Department offers to CERN users: the mail2SMS service. It allows any CERN e-mail account holder to send short messages (SMS) free of charge to CERN GSM phone numbers. Further to recent negotiations with our GSM operator, this service has been extended. It is now possible to send short messages free of charge to any Swiss mobile number. This extension of service aims at replacing the similar service that was made available by SWITCH(1) to CERN users (address: mobilenumber@sms.switch.ch). Because of repeated abuse, this service will be definitively stopped for CERN users on 15th January 2010. Please keep in mind that CERN’s e-mail to SMS service still has some restrictions: messages can only be sent from CERN mail accounts, and not from personal ones, such as GMAIL, MSN, Yahoo; the maximum length of the message is 160 characters (standard maximum SMS length); and only Swiss mobile...

Discovery and analysis of e-mail-driven business processes

NARCIS (Netherlands)

Stuit, Marco; Wortmann, Hans

E-mail is used as the primary tool for business communication and collaboration. This paper presents a novel e-mail interaction mining method to discover and analyze e-mail-driven business processes. An e-mail-driven business process is perceived as a human collaboration process that consists of

Teleradiology with DICOM e-mail: recommendations of rate at GIT; Teleradiologie mit DICOM E-mail: Empfehlungen der rate at GIT

Energy Technology Data Exchange (ETDEWEB)

Mildenberger, P.; Kaemmerer, M.; Klos, G.; Schuetze, B. [Klinik und Poliklinik fuer Radiologie, Johannes Gutenberg-Univ. Mainz (Germany); Engelmann, U. [Deutsches Krebsforschungszentrum, Abt. Medizinische und Biologische Informatik, Heidelberg (Germany); Ruggiero, S.; Runa, A.; Weisser, G. [Inst. fuer Klinische Radiologie, Universitaetsklinikum Mannheim (Germany); Schroeter, A. [CHILI GmbH, Heidelberg (Germany); Walz, M. [TUeV Industrie Service GmbH, TUeV-SUeD-Gruppe, Aerztliche Stelle fuer Qualitaetssicherung in der Radiologie, Eschborn (Germany)

2005-05-01

E-mail is ideal for ad-hoc connections in teleradiology. The DICOM standard offers the possibility to append DICOM data types as a MIME attachment to any e-mail, thus ensuring the transmission of the original DICOM data. Nevertheless, there are additional requirements (e.g. protection of data privacy) which must be obeyed. Because of the lack of given standards which would grant interoperability as well as manufacturer independence, teleradiology has not been established in Germany until today. Therefore, the IT-Team (Arbeitsgemeinschaft fuer Informationstechnologie, rate at GIT) of the Radiological Society of Germany (Deutsche Roentgengesellschaft, DRG) set up an initiative to standardise telemedicine by using e-mail. Its members agreed that an e-mail-based variant would be the most practicable way to a communication solution - as easy to implement as to use. In their opinion, e-mail represents the smallest common denominator for a safe data interchange that would fulfill the legal advantages for telemedicine in Germany. (orig.)

Technology Corner: Analysing E-mail Headers For Forensic Investigation

Directory of Open Access Journals (Sweden)

M. Tariq Banday

2011-06-01

Full Text Available Electronic Mail (E-Mail, which is one of the most widely used applications of Internet, has become a global communication infrastructure service.  However, security loopholes in it enable cybercriminals to misuse it by forging its headers or by sending it anonymously for illegitimate purposes, leading to e-mail forgeries. E-mail messages include transit handling envelope and trace information in the form of structured fields which are not stripped after messages are delivered, leaving a detailed record of e-mail transactions.  A detailed header analysis can be used to map the networks traversed by messages, including information on the messaging software and patching policies of clients and gateways, etc. Cyber forensic e-mail analysis is employed to collect credible evidence to bring criminals to justice. This paper projects the need for e-mail forensic investigation and lists various methods and tools used for its realization. A detailed header analysis of a multiple tactic spoofed e-mail message is carried out in this paper. It also discusses various possibilities for detection of spoofed headers and identification of its originator. Further, difficulties that may be faced by investigators during forensic investigation of an e-mail message have been discussed along with their possible solutions.

The Educational Impact of E-Mail: Extraverted versus Introverted Students.

Science.gov (United States)

Kunderewicz, Larisa; Michener, Stacey; Chambliss, Catherine

College students (N=151) completed surveys assessing the relationship between e-mail use and extraversion. The variables studied included time spent on e-mail; the frequency of e-mail usage; and the purposes e-mail served for each student. The results suggest that extraverts use e-mail as a form of procrastination more than introverts, and that…

PENGIRIMAN E-MAIL SPAM SEBAGAI KEJAHATAN CYBER DI INDONESIA

Directory of Open Access Journals (Sweden)

Eka Nugraha Putra

2018-01-01

Full Text Available The Internet is part of the development of technology, where the internet provides many impacts, both positive and negative. Currently, privacy issues on the internet have also become a complicated legal issue, this is due to quite a number of privacy-related issues, but not all countries in the world manage privacy issues on the internet. As a means of communicating the Internet has introduced e-mail that provides convenience and practicality. But in its development e-mail has an adverse impact on its users in the form of e-mail spam. In terms of its actions, sending spam e-mail is quite a disadvantage, even violate the privacy. Some countries have also set it to one type of cybercrime (cybercrime. This research will discuss e-mail spam in Indonesia, how the legislation in Indonesia see the action of this spam e-mail, is there any possibility of spam e-mail is criminalized as a cybercrime. The research will also look at how spam e-mails violate privacy and review and analyze internet privacy settings in Indonesia in relation to the criminalization of spam email.

Analysis of E-mail Transactions in Virtual Reference Services

Directory of Open Access Journals (Sweden)

Astutik Nur Qomariyah

2018-01-01

Full Text Available Today, the use of traditional reference desk in the academic libraries has been rarely used, thus expanding or even move to a virtual reference service. A minimum level of virtual reference services are provided in the academic library is currently in general is the electronic mail (e-mail. One of the academic library specifically provide virtual reference services via e-mail is a Petra Christian University (PCU Library (refdesk@petra.ac.id.. In such services librarians provide assistance to users in finding information and answer questions. This study aimed to analyze the transaction reference services virtually through e-mail at the PCU Library, with a view of the types of questions based on user background, the writing style of language communication interaction used based on user background, and cultural values are revealed behind the user in virtual reference services (e-mail. This study uses content analysis (content analysis of the transcript e-mail received librarians of reference services began March 10 until June 16, 2015. The results showed that the types of questions asked in reference service virtual (e-mail in the Library UK Petra include: specific search, access online resources, operation of online resources, policies and procedures for services, and library holdings with background the student (PCU and non-PCU, faculty, and librarians. Based on the background of users found that overall more types of questions asked in virtual reference services (e-mail is a problem of access to online resources, and generally submitted by the students. Then, the writing style of the user's language in interaction reference service virtual (e-mail tends to be formal, which includes the word greeting, the message will be delivered, and regards cover, either by the student (PCU and non-PCU, lecturer, or librarians. While cultural values that revealed the background behind the user in virtual reference services (e-mail is obedience, courtesy and

The impact of e-mail in acquiring and retaining whole-blood donors: a comparative analysis of the Puget Sound Blood Center donor e-mail communication program.

Science.gov (United States)

Geyer, Maria Elena

2005-12-01

With the emergence of e-mail as a common form of communication, it is important to understand the role and impact e-mail can have on acquiring and retaining whole-blood donors. Whole-blood donors who opted in to receive e-mail communications (n = 43,232) from the Puget Sound Blood Center (PSBC) and as a result participated in one or more of five e-mail marketing campaigns between July 2002 and March 2003 were studied. New donors with e-mail addresses grew by 74 percent over the measurement period compared with 2 percent growth of those without e-mail addresses. Nearly 15,000 prospective donors were reached as a result of donors passing along e-mails they received from PSBC to friends and family. Nearly 5 percent of PSBC e-mail campaign recipients registered to donate online. PSBC e-mail campaigns have outperformed e-mail marketing industry mean open rates by 44 percent and click-through rates by 36 percent. E-mail is now a mainstream communication medium. It has proven to be an effective method of reaching new donors and generating new donation registrations. Donors respond more favorably to e-mail communications from PSBC compared with e-mail they receive from other organizations. Deeper understanding of how different segments of blood donors use e-mail may help blood centers adjust their donor acquisition and retention programs. New recruitment methods are needed to grow the overall donor base, and e-mail appears to have the potential to make a significant contribution to meeting this objective.

Direct e-mail marketing: Case of Serbia

Directory of Open Access Journals (Sweden)

Končar Jelena A.

2005-01-01

Full Text Available Direct e-mail marketing refers to approaching customers directly, without employing intermediaries. It represents a direct mode of communication with the target population, which affects the creation of stronger and more loyal relationships with prospective customers, compared to traditional direct marketing resources (TV, radio, print and advertising panels, etc. The main goal of direct e-mail marketing is building long-term "one to one" relationships with current and prospective customers. Direct e-mail marketing is not aimed at momentary sale, but at boosting certain product preferences due to the engagement of numerous electronic media.

Fusion special: E.ON/Ruhrgas, EDF/Gaz de France? Trends. Interview. Inquiry. Portrait

International Nuclear Information System (INIS)

Schneid, O.; Carbier, M.Ch.

2003-01-01

This issue of 'Energies news' newsletter comprises 6 articles dealing with: the E.ON/Ruhrgas fusion and the birth of a leader of the gas-electric power convergence in Europe (the serial story of the fusion, the compromise with the adverse parties); the key economical data of RWE; the proposal of fusion between EdF (Electricite de France) and Gaz de France (interview of M. Boiteux, honorary president of EdF); the reorganization of RWE activities in France (interview of R. Felgentreff, head of RWE Solutions France); travel inside the French power market (part.2: opening of the power market to all professionals); portrait of J. Masdeu-Arus, co-president of a study group at the French house of commons, who made a report about the economical and financial situation of EdF. (J.S.)

EdF-Gaz de France. No merger without dismembering

International Nuclear Information System (INIS)

Lepetit, V.

2007-01-01

Gathering together the two historical French energy monopolies, Electricite de France (EdF) and Gaz de France (GdF), and warranting low electricity and gas prices is still an attractive idea for some political and syndicate representatives. However, such a merger would create a dominating position which is forbidden with respect to Brussels criteria. (J.S.)

SPAM: Beware of e-mails asking for passwords

CERN Multimedia

IT Department

2008-01-01

CERN’s Computing Rules (Operational Circular No. 5) require that passwords remain confidential and never be given to anyone, not even helpdesk or other support personnel. If you think that your password could have been exposed then you must immediately change it. Cybercriminals are making growing use of fake e-mail messages and Web sites to steal account and identity information from users. This technique is called ‘phishing’. The fake e-mails often look real and try to trick you into giving your password or other personal data. CERN has recently been targeted by a fake e-mail message which requested users to send their username, password and date of birth. This case was promptly blocked by the CERN Mail Service, but future cases may still occur. Users need to be vigilant regarding any requests for passwords or personal data. Fake e-mails should be immediately deleted. In case of questions on this topic, you may contact mailto:helpdesk@cern.ch. CERN IT Department

Publication’s e-mail marketing procedure

OpenAIRE

Ebrahim, Nader Ale

2016-01-01

Your research findings and publications have to reach thousands of your peers and colleagues by sending an email. If you have recently published a study that would be of interest to others in your field, market it through email. “E-mail marketing” allow the researchers to increase the research impact and citations for their publications. This workshop will provide various techniques to increase the visibility and enhance the impact of researcher’s output by employing the publications E-mail m...

Analysis of E-mail Transactions in Virtual Reference Services

Directory of Open Access Journals (Sweden)

Astutik Nur Qomariyah

2016-01-01

Full Text Available Today, the use of traditional reference desk in the academic libraries has been rarely used, thus expanding or even move to a virtual reference service. A minimum level of virtual reference services are provided in the academic library is currently in general is the electronic mail (e-mail. One of the academic library specifically provide virtual reference services via e-mail is a Petra Christian University (PCU Library (ref-desk@petra.ac.id.. In such services librarians provide assistance to users in finding information and answer questions. This study aimed to analyze the transaction reference services virtually through e-mail at the PCU Library, with a view of the types of questions based on user background, the writing style of language communication interaction used based on user background, and cultural values are revealed behind the user in virtual reference services (e-mail. This study uses content analysis (content analysis of the transcript e-mail received librarians of reference services began March 10 until June 16, 2015. The results showed that the types of questions asked in reference service virtual (e-mail in the Library UK Petra include: specific search, access online resources, operation of online resources, policies and procedures for services, and library holdings with background the student (PCU and non-PCU, faculty, and librarians. Based on the background of users found that overall more types of questions asked in virtual reference services (e-mail is a problem of access to online resources, and generally submitted by the students. Then, the writing style of the user's language in interaction reference service virtual (e-mail tends to be formal, which includes the word greeting, the message will be delivered, and regards cover, either by the student (PCU and non-PCU, lecturer, or librarians. While cultural values that revealed the background behind the user in virtual reference services (e-mail is obedience, courtesy and

PHS terminal 'TEGACKY' dedicated to e-mailing; Mail senyo PHS tanmatsu 'TEGACKY

Energy Technology Data Exchange (ETDEWEB)

NONE

2000-03-01

The e-mail utilization rate at mobile communication terminals is increasing at a remarkable rate, as if to grow above the rate of communication by voice. Under the circumstances, a PHS (Personal Handyphone System) terminal 'TEGACKY' (type name: PM-T101) has been developed, designed exclusively for use for e-mailing. 'TEGACKY' is characterized in that its icons may be activated with pen, that input may be made by handwriting, and that its large screen allows a 48-character message consisting of 4 lines of 12 characters to be displayed at one time despite its compact size. It can also perform communication directly with other terminals or e-mail via center, and is provided with an information service function. 'TEGACKY' having such distinguished features has created a new category of terminals which are at once e-mailing tools. (translated by NEDO)

Direct e-mail marketing: Case of Serbia

OpenAIRE

Končar Jelena A.; Vukmirović Goran; Katai Žita

2005-01-01

Direct e-mail marketing refers to approaching customers directly, without employing intermediaries. It represents a direct mode of communication with the target population, which affects the creation of stronger and more loyal relationships with prospective customers, compared to traditional direct marketing resources (TV, radio, print and advertising panels, etc). The main goal of direct e-mail marketing is building long-term "one to one" relationships with current and prospective customers....

Securing E-mail Communication Using Hybrid Cryptosystem on Android-based Mobile Devices

Directory of Open Access Journals (Sweden)

Andri Zakariya

2012-12-01

Full Text Available One of the most popular internet services is electronic mail (e-mail. By using mobile devices with internet connection, e-mail can be widely used by anyone to exchange information anywhere and anytime whether public or confidential. Unfortunately, there are some security issues with email communication; e-mail is sent in over open networks and e-mail is stored on potentially insecure mail servers. Moreover, e-mail has no integrity protection so the body can be undectected altered in transit or on the e-mail server. E-mail also has no data origin authentication, so people cannot be sure that the emails they receive are from the e-mail address owner. In order to solve this problem, this study proposes a secure method of e-mail communication on Android-based mobile devices using a hybrid cryptosystem which combines symmetric encryption, asymmetric encryption and hash function. The experimental results show that the proposed method succeeded in meeting those aspects of information security including confidentiality, data integrity, authentication, and non-repudiation.

Open-Rate Controlled Experiment in E-Mail Marketing Campaigns

OpenAIRE

Biloš, Antun; Turkalj, Davorin; Kelić, Ivan

2016-01-01

Purpose – The main purpose of this paper is to test the controlled experiment (A/B split) methodology in B2C oriented e-mail marketing campaigns. Design/Methodology/Approach – E-mail marketing techniques have been a substantial part of e-marketing methodology since the early Internet days of the mid-1990s. From the very beginning of Internet utilization for business purposes, e-mail was one of the most widely used communication techniques in B2B and B2C markets alike. Due to high volumes o...

Open-Rate Controlled Experiment in E-Mail Marketing Campaigns

Directory of Open Access Journals (Sweden)

Antun Biloš

2016-06-01

Full Text Available Purpose – The main purpose of this paper is to test the controlled experiment (A/B split methodology in B2C oriented e-mail marketing campaigns. Design/Methodology/Approach – E-mail marketing techniques have been a substantial part of e-marketing methodology since the early Internet days of the mid-1990s. From the very beginning of Internet utilization for business purposes, e-mail was one of the most widely used communication techniques in B2B and B2C markets alike. Due to high volumes of spamming and progression of online communication clutter, some practitioners began to question the usability of e-mail as a marketing communication channel, while others embarked on working on improving the message itself. Efforts were invested into improving message quality, as well as into better understanding user expectations. One of the most commonly used techniques to test specific e-mail message elements is the controlled experiment. Findings and implications – This paper explores several types of controlled experiments in a specific Croatian B2C market. Tests were run to determine subscriber behavior towards several newsletter components, including sending time, sending day, sender’s name, and subject line. Open and click rates for tested campaigns, and several other metrics were investigated using MailChimp software. An N − 1 two-proportion test using an adjusted Wald confidence interval around the difference in the proportions was used for comparing the open-rate measure in the controlled experiments between subjects. Limitation – Controlled experiments (A/B split tests showed a lot of potential as a way of measuring behavior and preferences of subscribers, although several apparent limitations (the data-set scope, comparability issues indicated a clear need for standardization on a managerial and scientific level. Originality – This paper provides an up-to-date e-mail marketing effectiveness literature review, describes and tests the

Mael-e(st-France

Directory of Open Access Journals (Sweden)

Le Mée, Mael

2016-09-01

Full Text Available A performance of Mael Le Mée and France Geoffroy Photos and videos (France: Denis Louis Photo (Montreal: Alexandre Cv France Geoffroy’s assistant: Rosalie Chrétien Production: Espace Projet and Dorsa Barlow Performance co-developed within the project BIOGRAPHIES, with the support of CNC – DICRéAM, Aquitaine Regional Council and the City of Bordeaux.

Mortal waiting for EdF and Gaz de France

International Nuclear Information System (INIS)

Jemain, A.

2003-01-01

Electricite de France (EdF) and Gaz de France (GdF) utilities have announced important investment programs for the forthcoming opening of gas and electricity markets to 2.5 millions of professionals by July 1, 2004. However, nothing can be done before the approval of the French government has been given for the change of their statuses (from the industrial and commercial public company status to the anonymous company status) and for the opening of their capital. Short paper. (J.S.)

E-Mail at Work: Is it Really Private?

Science.gov (United States)

Rosenblum, Cindy

This paper examines the controversy of e-mail privacy in the workplace. Once an employee uses an e-mail system that belongs to the employer, according to recent case law, their privacy rights are forfeited. Employers will now have to start creating policies to safeguard themselves from expensive litigation, and employees will have to be more…

Teleradiology with DICOM e-mail: recommendations of rate at GIT

International Nuclear Information System (INIS)

Mildenberger, P.; Kaemmerer, M.; Klos, G.; Schuetze, B.; Engelmann, U.; Ruggiero, S.; Runa, A.; Weisser, G.; Schroeter, A.; Walz, M.

2005-01-01

E-mail is ideal for ad-hoc connections in teleradiology. The DICOM standard offers the possibility to append DICOM data types as a MIME attachment to any e-mail, thus ensuring the transmission of the original DICOM data. Nevertheless, there are additional requirements (e.g. protection of data privacy) which must be obeyed. Because of the lack of given standards which would grant interoperability as well as manufacturer independence, teleradiology has not been established in Germany until today. Therefore, the IT-Team (Arbeitsgemeinschaft fuer Informationstechnologie, rate at GIT) of the Radiological Society of Germany (Deutsche Roentgengesellschaft, DRG) set up an initiative to standardise telemedicine by using e-mail. Its members agreed that an e-mail-based variant would be the most practicable way to a communication solution - as easy to implement as to use. In their opinion, e-mail represents the smallest common denominator for a safe data interchange that would fulfill the legal advantages for telemedicine in Germany. (orig.)

Legal and policy issues associated with monitoring employee E-mail

Energy Technology Data Exchange (ETDEWEB)

Segura, M.A.; Rither, A.C.

1997-01-01

This paper examines the legal issues involved with employer monitoring of employee e-mail. In addition to identifying pertinent legal issues, the paper provides guidelines that will help the Pacific Northwest National Laboratory (PNNL) establish a program for monitoring outgoing e-mail to insure compliance with company policies, particularly those regarding protection of trade secrets and proprietary information, and to comply with the Department of Energy`s (DOE) procedures for protecting Export Controlled Information (ECI). Electronic communication has allowed companies to enhance efficiency, responsiveness and effectiveness. E-mail allows employees to transmit all types of data to other individuals inside and outside of their companies. The ease with which information can be transmitted by e-mail has placed trade secrets, proprietary information, and other sensitive data at risk from inadvertent disclosure by employees. As employers attempt to protect their interests through measures such as monitoring e-mail, they may expose themselves to liability under federal and state laws for violating employee privacy. Business use of e-mail has proliferated so rapidly that the federal and state legal systems have not been able to adequately address the issues arising out of its use in the workplace.

Discourse strategies in professional e-mail negotiation

DEFF Research Database (Denmark)

Jensen, Astrid

2009-01-01

The purpose of this article is to report on some of the preliminary results of an on-going study on the use of discourse strategies in e-mail negotiation. The analysis aims at showing how relations between the participants develop through the use of specific discourse strategies in their e......-mail communication which covers a period of three months, during which the relationship progresses from initial contact to on-going business. Drawing on Hyland's (2005) concept of metadiscourse combined with Charles' (1996) categories of ‘old and new relationship negotiations', this study provides insights...

Private E-Mail Requests and the Diffusion of Responsibility.

Science.gov (United States)

Barron, Greg; Yechiam, Eldad

2002-01-01

Discussion of e-mail technology and requesting information from multiple sources simultaneously focuses on an experiment demonstrating that addressing e-mails simultaneously to multiple recipients may actually reduce the number of helpful responses. Discusses diffusion of responsibility and implications for the application of social cueing theory…

Using E-mail in a Math/Computer Core Course.

Science.gov (United States)

Gurwitz, Chaya

This paper notes the advantages of using e-mail in computer literacy classes, and discusses the results of incorporating an e-mail assignment in the "Introduction to Mathematical Reasoning and Computer Programming" core course at Brooklyn College (New York). The assignment consisted of several steps. The students first read and responded…

The Application of E-Mail to College English Teaching in China

Science.gov (United States)

Wang, Guofeng

2010-01-01

With the development of information technology in the past 10 years, e-mail has been widely used in the field of English teaching. This paper, based on an analysis of the ways of using e-mail in college English teaching in China, probes the feasibility and the benefits of application of e-mail to college English teaching.

A Discourse Analysis of School Counseling Supervisory E-Mail

Science.gov (United States)

Luke, Melissa; Gordon, Cynthia

2011-01-01

This article is a discourse analysis of weekly computer-mediated communications between 8 school counseling interns and their e-mail supervisor over a 16-week semester. Course-required e-mail supervision was provided as an adjunct to traditional face-to-face individual and group supervision. School counselor supervisees and supervisor enacted 3…

A survey to evaluate patients' perspective concerning e-mail in an oncology practice

International Nuclear Information System (INIS)

Katzen, C.S.; Dicker, A.P.

2001-01-01

Purpose: Use of e-mail to improve physician-patient communication is becoming increasingly widespread, however, little research has been done to evaluate patients' interest and concerns regarding this technology. The goals of this study were to (1) evaluate the effectiveness of e-mail for communication between patients and their oncologist and (2) assess from the perspective of the patient the accessibility and usefulness of e-mail to facilitate medical treatment and advice as compared to conventional mail and telephone. E-mail as a clinical tool is a new trend in medicine that is growing quickly, however, there are few reports to date that evaluate the patients' perspective concerning e-mail usage. The use of e-mail in doctor-patient communication is potentially faster and more efficient than conventional mail and may reduce 'telephone tag'. E-mail initiated by the physician also allows for potential follow-up after treatment. Our study evaluated the types of transactions (personal medical questions, referrals, etc.) for which patients' preferred using e-mail in place of conventional communication methods. Materials and Methods: A self-administered survey (8 pages; 50 items) was mailed to 65 patients who were treated within the previous three years for prostate cancer in a radiation oncology practice. This survey explored the opinions and behaviors of patients with regard to online communication about general healthcare issues. The items included: patients' interest in e-mail, comfort in using e-mail, concerns about confidentiality, and access to e-mail. Patients' interest in using e-mail for specific situations were also evaluated, such as, making appointments, following up on treatment, or asking general health related questions. Patients' concerns about using email to communicate with healthcare organizations also were assessed. Results: The response rate to the survey was 63%, with a median age of 68 years (range 53-82), and the majority of respondents were

BEWARE OF OPENING ATTACHMENTS IN E-MAIL

CERN Multimedia

2000-01-01

Following the recent e-mail viruses you are asked to be cautious when opening e-mail attachments on your PC. Attachments that are apparently harmless might hide active content producing nasty effects as soon as they are opened. Some of these so called 'Trojan horses' can conceal themselves in very attractive pictures and funny slide shows.On the PC Windows infrastructure, CERN runs software to protect users from known viruses, but new ones can sometimes arrive before our software recognises them. They can enter your system when you open an attachment. To remove them it may be necessary to re-install the Windows software on your PC.

Analyzing E-mail communication of prospective learners

Directory of Open Access Journals (Sweden)

Anurag SAXENA

2005-10-01

Full Text Available Analyzing E-mail communication of prospective learners Vibha JOSHIAnurag SAXENA Reader School of Management IGNOU, New Delhi, INDIA ABSTRACT Today, computer has replaced all means of communication significantly. E-mail is the most popular means of communication through computers. It has vanished the boundaries between the cities, countries and continents. Earlier Studies that used this medium, had shown evidence of higher quality of responses and also significant cost savings feature of this method (mainly for convenience of dispatch for research purposes. In this communication, an attempt has been made to utilize email responses of prospective learners in education discipline based programs offered through open learning system. The inception of this study is linked to the creation of website (http://www.ignou.ac.in/ and availability of information related to all activated and prospective programs of studies, various school of studies, faculty email addresses and faculty vis-à-vis program coordinator in the University. The present study analyzed 65 email responses received from July 2002 to till date by the researcher on her email ID. These respondents got the email ID from the University website and due to their eagerness to attain qualifications in the field of education/guidance/educational management, sent an e-mail to the program coordinator(s. These email responses were analyzed in order to visualize the learner profiles and viability of the ongoing as well as prospective programs of studies. This paper tries to analyze the e-mail responses of the people who either by surfing IGNOU’s website or from other sources came to know about the various programs of studies offered by the School of Education. The study validates that there is an amount of hidden information even in the curiosity of the learners.

Unraveling mulitple translatorship through an e-mail correspondence

DEFF Research Database (Denmark)

Jansen, Hanne

2017-01-01

The aim of this study is to shed light on questions of “multiple translatorship” and particularly on translation collaboration processes. The empirical material consists of more than three hundred e-mails exchanged between two co-translators who translated Claudio Magris’s novel Alla cieca (2005......) into Danish. The theoretical framework presents a double perspective through which the e-mail correspondence is studied: on the one hand, as an ethnographic “thick description” (focusing on translation as an event), with the aim of uncovering who the agents involved are, how they interact, and what...

E-mail security a pocket guide

CERN Document Server

Furnell, Steven

2010-01-01

This pocket guide will help businesses to address the most important issues. Its comprehensive approach covers both the technical and the managerial aspects of the subject, offering valuable insights for IT professionals, managers and executives, as well as for individual users of e-mail.

Secure e-mail and Web browsing

CERN Multimedia

CERN. Geneva

2009-01-01

This is an entry-level 1.5-hour training course aimed to show how to detect and avoid typical security pitfalls encountered when e-mailing and browsing the Web. It is designed for non-technical users of Internet Explorer and Outlook. Register at CTA

21ST International Symposium on Rarefied Gas Dynamics. Marseille (France) 26-31 July 1998. Book of Abstracts: Volume III, Special Session; Molecular Beams.

Science.gov (United States)

1998-07-30

Tejeda, J. M. Fernandez, and A. Ramos Instituto de Estructura de la Materia, CSIC. Serrano 121, 28006 Madrid, Spain Introduction vantages over other...Gaulle, 91400 Orsay, France T61. : 01 69 28 01 05 - Fax : 01 69 28 00 78 - E-mail : Tchnscfr@aol.com S A R L au capital de 210 000 F - R.C.S. Corbeil B...Tchnscfr@aol.com S A R L au capital de 210 000 F - R.C.S. Corbell B 339 966 152 - Siret 339 966 152 00029

Promotion and communication through e-mail marketing campaigns

Directory of Open Access Journals (Sweden)

Raluca Dania TODOR

2017-07-01

Full Text Available The main purpose of this article is to try to emphasize the e-mail marketing campaigns importance and efficiency and the way they increase the interaction between a company and potential customers and to increase their interest in a company’s products and services and finally trigger the buying decision. Also the present paper’s aim is to exemplify how business can gain benefits by using marketing automation tools like e-mail marketing campaigns which is considered nowadays a form of direct marketing which is less expensive than the traditional direct marketing alternatives.

Perceptions and use of e-mail among Universiti Utara Malaysia staff: A pilot study

Science.gov (United States)

Mohamed, Shafinah Farvin Packeer; Ku-Mahamud, Ku Ruhana; Ramli, Razamin; Abdullah, Kamarudin

2017-10-01

The use of e-mail has become common either for work purposes or personal usage. Despite its usefulness, complain about the overwhelming messages received which cause the users to have problem in managing those messages. Similar situation occurred among Universiti Utara Malaysia (UUM) staff. Thus, a pilot study was conducted to investigate its staff's perception and use of e-mail in order to improve the e-mail service provided to them. This paper discusses the findings from the pilot study, which involves 41 UUM staff. Self-administered questionnaires were used to gather the data, while descriptive statistical analysis was used for data analysis. The findings of the study reveal that UUM staff appreciate the e-mail service. However they faced problems like limited storage size and overwhelming e-mails. They think that UUM e-mail is being abused by the repeating advertisements and news sent to them. The output of this study can be used as a guideline by the UUM management in revising its e-mail policy to serve better quality of e-mail service.

Con Artists Attack Colleges with Fake Help-Desk E-Mail

Science.gov (United States)

Young, Jeffrey R.

2008-01-01

An e-mail scam has hit tens of thousands of users at dozens of colleges over the past few weeks, leaving network administrators scrambling to respond before campus computer accounts are taken over by spammers. Students, professors, and staff members at the affected colleges received e-mail messages that purported to come from the colleges' help…

The STRENGTH Ezine: an application of e-mail for health promotion in adolescent girls.

Science.gov (United States)

Abroms, Lorien C; Fagan, Pebbles; Eisenberg, Marla E; Lee, Hye-Seung H; Remba, Natania; Sorensen, Glorian

2004-01-01

Few studies have investigated the efficacy of e-mail for promoting behavior change. This study evaluates the participation in and outcomes associated with an e-mail-based health promotion program. Adolescent girls aged 15 to 17 years were recruited at a shopping mall. Participants with an e-mail address were assigned to the interactive e-mail magazine (Ezine) group (n = 37), whereas those not reporting an e-mail address were assigned to the non-Ezine group (n = 33). Participants in the Ezine group received the health Ezine, which included a quiz and an advice column, on a weekly basis. Results indicate that among the Ezine group, there was a high recall of the Ezine (81.1%), and more than one third of the participants replied to Ezine volumes with quiz answers or an advice question (36.6%). Differences in health behavior change between the Ezine and non-Ezine groups were not significant. E-mails on health-related matters can generate moderate levels of involvement in adolescent girls. Given the widespread use of e-mail, more studies are needed on the effective application of e-mail for health behavior change.

THE DEVELOPMENT OF E-MAIL LITERACY: FROM WRITING TO PEERS TO WRITING TO AUTHORITY FIGURES

Directory of Open Access Journals (Sweden)

Chi-Fen Emily Chen

2006-05-01

Full Text Available Though e-mail has become a common interpersonal communication medium, it does not mean that this medium is used without difficulty. While people can write e-mails to peers in any manner they like, writing e-mails to authority figures requires higher pragmatic competence and critical language awareness of how discourse shapes and reflects power asymmetry in an institutional context. For L2 learners, the challenge of composing this type of e-mail can be greater due not only to their limited linguistic ability but also their unfamiliarity with the target culture's norms and values. To provide a deeper understanding of how an L2 learner develops e-mail literacy in the target language environment, this paper presents a longitudinal case study of a Taiwanese graduate student’s e-mail practice in English during her studies at a U.S. university for two and a half years. Using a critical discourse analysis approach, the study reveals the complexity of an L2 learner’s evolving e-mail practice and struggle for appropriateness, particularly in her e-mail communication with professors. Her development of e-mail literacy is discussed in relation to her evolving understanding of the e-mail medium, changing performance of student identity, increasing knowledge of student-professor interaction and realization of culture-specific politeness.

E-mail Writing: Providing Background Information in the Core of Computer Assisted Instruction

Directory of Open Access Journals (Sweden)

Behzad NAZARI

2015-01-01

Full Text Available The present study highly supported the effective role of providing background information via e-mail by the teacher to write e-mail by the students in learners’ writing ability. A total number of 50 EFL advanced male students aged between 25 and 40 at different branches of Iran Language Institute in Tehran, Tehran. Through the placement test of Oxford English Language Placement Test (OELPT the students' proficiency level seems to be nearly the same. Participants were randomly assign into two groups of experimental and control, each consisting of 25 students. After the administration of the proficiency test, all groups were assigned to write topic 1 as the pre-test. Next, the teacher involved the learners in the new instruction (treatment. During writing topics 2, 3, 4, 5, 6, and 7 experimental group’s background knowledge was activated through e-mail before writing and e-mailing topics while the control group received no background knowledge activation through e-mail. After the treatment was given to the experimental group, the students in both groups were required to write another composition about the last topic, topic 8. Again, in this phase, none of the groups received any background information. The results indicated that providing background information via e-mail by the teacher to write e-mail by the students significantly improved learners’ writing ability.

Suspecting Neurological Dysfunction From E Mail Messages ...

African Journals Online (AJOL)

A non medical person suspected and confirmed neurological dysfunction in an individual, based only on e mail messages sent by the individual. With email communication becoming rampant “peculiar” email messages may raise the suspicion of neurological dysfunction. Organic pathology explaining the abnormal email ...

Location Is Everything: The Use and Marketing of Reference E-Mail

Science.gov (United States)

Collins, Susan L.

2006-01-01

Reference e-mail continues to be a vital reference service. This article studies the trends in reference e-mail use over an eight year period. Usage statistics are analyzed particularly in light of the marketing of the service via changes in the location of the service on the official university libraries' Web pages. Included are recommendations…

Computer Security: e-mail is broken and there is nothing we can do

CERN Multimedia

Stefan Lueders, Computer Security Team

2016-01-01

Have you ever received an e-mail from a friend or someone you know and been surprised or appalled by its contents? Or, worse, have you have received a response to an e-mail that wasn’t written by you? Maybe with similarly surprising or appalling contents? If yes, welcome to the insecurity of the mail protocol, where nothing is as it seems…   No, this time we are not talking about “phishing” or malicious attachments but the very basics of the e-mail protocol. “SMTP” aka the “Simple Mail Transfer Protocol” is exactly what it says: very simple! In many respects, e-mails are identical to physical hand-written letters: you cannot deduce from the sender’s address nor from the message text whether it has really been sent by that person. Impersonation has never been as easy as with the SMTP protocol. Due to its simple design, I can pretend to be Mickey Mouse, Harry Potter or anyone else, and send you text messages...

Kajian Kesantunan dalam E-Mail Permohonan yang Ditulis oleh Penutur Jepang dan Pembelajar Indonesia

Directory of Open Access Journals (Sweden)

Hani Wahyuningtias

2014-05-01

Full Text Available Nowadays electronic mail (e-mail is a communication tool that is often used in everyday life. One of the utilizations of e-mail is used in practical purposes such as making a request. This paper provided views on linguistic politeness in submitting an e-mail containing the request based on e-mail data written by native speakers of Japanese (J and the Indonesian Japanese language learners (IJL. The data was analyzed using the theory of politeness expressed by Brown and Levinson. This paper focused on the strategy that what more likely was to be used by J and IJL in the expression of request. In the final part, it concluded the view about what should be considered in connection with the linguistic politeness in Japanese e-mail containing request. It was intended for learners of foreign language, especially Indonesian people, to know the limitation of politeness, so that IJL will not repeat the same mistakes in the future.

Does E.D.F. export at a loss

International Nuclear Information System (INIS)

Laramee, V.

1996-01-01

As European Energy markets should progressively open themselves to the free competition, Electricite de France (E.D.F.) is suspected by an energy research institute to sell abroad its kilowatts at a price inferior to the production cost. The situation and the different parameters to calculate the production cost are explained here. (N.C.)

COMMUNICATION TOPICS AND STRATEGIES IN E-MAIL CONSULTATION: COMPARISON BETWEEN AMERICAN AND INTERNATIONAL UNIVERSITY STUDENTS

Directory of Open Access Journals (Sweden)

Sigrun Biesenbach-Lucas

2005-05-01

Full Text Available On today's "wired" college campuses, students avail themselves in increasing numbers of electronic channels, most notably e-mail, as a means to consult with their professors. While some research has investigated the purposes for which university students communicate with their instructors via e-mail, little research has examined differences in e-mail use between American and international students. In the present study, e-mail messages sent by American and international students enrolled in a teacher-preparation program to their professor were collected over the course of one semester. The messages were examined for three major communication topics (facilitative, substantive, relational and communication strategies (requesting, negotiating, reporting. Results indicate quantitative and qualitative differences in American and international students' e-mail topics and strategies, suggesting, similar to findings for face-to-face academic advising sessions, that American students demonstrate greater initiative and ability to adapt to the spatial and temporal remoteness between interlocutors in e-mail interaction, especially when using e-mail to solicit face-to-face appointments and input on projects. Findings also show that messages from both groups of students contained substantial relational communication, perhaps in an attempt to compensate for the lack of visual and paralinguistic clues in the e-mail medium.

Development of an E-mail Application Seemit and its Utilization in an Information Literacy Course

Science.gov (United States)

Kita, Toshihiro; Miyazaki, Makoto; Nakano, Hiroshi; Sugitani, Kenichi; Akiyama, Hidenori

We have developed a simple e-mail application named Seemit which is designed for being used in information literacy courses. It has necessary and sufficient functionality of an e-mail application, and it has been developed for the purpose of learning basic operations and mechanisms of e-mail transfer easily. It is equipped with the function to automatically set the configuration of user's SMTP/POP servers and e-mail address, etc. The process of transferring e-mail via SMTP and POP can be demonstrated step by step showing actual messages passed during the client-server interaction. We have utilized Seemit in a university-wide information literacy course which holds about 1800 students.

Communicative In-Betweens of E-mail Communication

DEFF Research Database (Denmark)

Hansen, Ejvind

2009-01-01

In this paper I seek to deconstruct internet-based communication. I highlight Derrida’s focus on the margins and in-betweens of communication, and relate it to the genre of e-mail. I argue (i) that the silence between the dialogic turns becomes more marked, while (ii) the separation of present an...

Impact of predictive scoring model and e-mail messages on African American blood donors.

Science.gov (United States)

Bachegowda, Lohith S; Timm, Brad; Dasgupta, Pinaki; Hillyer, Christopher D; Kessler, Debra; Rebosa, Mark; France, Christopher R; Shaz, Beth H

2017-06-01

Expanding the African American (AA) donor pool is critical to sustain transfusion support for sickle cell disease patients. The aims were to: 1) apply cognitive computing on donation related metrics to develop a predictive model that effectively identifies repeat AA donors, 2) determine whether a single e-mail communication could improve AA donor retention and compare retention results on higher versus lower predictive score donors, and 3) evaluate the effect of e-mail marketing on AA donor retention with culturally versus nonculturally tailored message. Between 2011 and 2012, 30,786 AA donors donated blood at least once on whom predictive repeat donor scores (PRDSs) was generated from donor-related metrics (frequency of donations, duration between donations, age, blood type, and sex). In 2013, 28% (8657/30,786) of 2011 to 2012 donors returned to donate on whom PRDS was validated. Returning blood donors had a higher mean PRDS compared to nonreturning donors (0.649 vs. 0.268; p e-mail pilot, high PRDS (≥0.6) compared to low PRDS (e-mail opening rate (p e-mail, 159% higher presentation rate (p e-mail communication has the potential to increase the efficiency of donor marketing. © 2017 AABB.

Teleradiology applications with DICOM-e-mail

International Nuclear Information System (INIS)

Weisser, G.; Ruggiero, S.; Runa, A.; Engelmann, U.; Schroeter, A.; Baur, S.; Walz, M.

2007-01-01

For the connection of several partners to a Dicom-e-mail based teleradiology network concepts were developed to allow the integration of different teleradiology applications. The organisational and technical needs for such an integration were analysed. More than 60 institutions including 23 hospitals in the Rhein-Neckar-Region, Germany were connected. The needed functionality was grouped in six teleradiology applications (emergency consultation, tele-guided examinations, expert consultations, cooperative work, scientific cooperations and homework with on call services) and their technical and organisational needs according to availability, speed of transfer, workflow definitions and data security needs was analysed. For the local integration of teleradiology services the setup and workflow is presented for a standalone teleradiology workstation and a server based teleradiology gateway. The line type needed for different groups of applications and users is defined. The security concept and fallback strategies are laid out, potential security problems and sources of errors are discussed. The specialties for the emergency teleradiology application are presented. The DICOM-e-mail protocol is a flexible and powerful protocol that can be used for a variety of teleradiology applications. It can meet the conditions for emergency applications but is limited if synchronous applications like teleconferences are needed. (orig.)

An E-mail Service in a Military Adolescent Medicine Clinic: will teens ...

African Journals Online (AJOL)

The goal of this study was to determine utilization patterns of an Adolescent Medicine Clinic e-mail service. An e-mail service was offered to 6134 patients presenting for care to a military Adolescent Medicine Clinic in San Antonio, Texas over a 6-month period. Families had to complete an authorization form acknowledging ...

Colleges Get out of E-Mail Business

Science.gov (United States)

Carnevale, Dan

2008-01-01

Frantic troubleshooting by an overworked staff versus someone else fixing problems smoothly. A sliver of server space per person versus a five-gigabyte chunk. Half a million dollars versus free. That's what colleges are faced with as they decide whether to continue running their own e-mail services or outsource them to a professional service like…

Using viral e-mails to distribute tobacco control advertisements: an experimental investigation.

Science.gov (United States)

Carter, Owen B J; Donovan, Robert; Jalleh, Geoffrey

2011-08-01

The authors' objective was to conduct a trial of viral e-mail marketing as a distribution method for tobacco control advertisements. University students (n = 200) in the state of Western Australia were randomly allocated to receive 1 of 2 e-mails with hyperlinks to tobacco control advertisements ("Toilet" and "Rubbish") emphasizing the disgusting nature of smoking. Recipients followed a hyperlink to a Web page playing Toilet or Rubbish on endless loop. Viewers were encouraged to forward the e-mail to their friends and invited to complete an online survey about the advertisement. Unique downloads for each advertisement were identified by internet provider (IP) location and tallied by date and geographical location to assess subsequent dissemination beyond the initial 200 students. There were 826 unique viewings of the advertisements averaging 26.9 viewings per day for the first fortnight, followed by a lower average of 4.1 hits per day for the next 3.5 months. IP addresses identified hits from 3 other Australian states and 7 other countries. Online surveys were completed by 103 respondents (12.5% of total hits) but included few smokers (n = 9). Significantly more respondents rated Toilet as "funny" compared with Rubbish (40% vs. 11%; p e-mail sent but daily hits rapidly deteriorated over time. Entertainment appears to facilitate viral e-mails being forwarded onwards but only exceptionally compelling tobacco control materials are ever likely to become self-perpetuating.

Cycle e-business: the e-business of Gaz De France; Cycle e-business: l'e-business de Gaz de France

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

This paper deals with the Gaz De France Group position in the e-business context. In terms of e-business, all is done to put Internet at the marketing service. Three examples of Internet sites realization and the future policy are presented. (A.L.B.)

E-mail et Web : pour une navigation sans risque

CERN Multimedia

CERN. Geneva

2010-01-01

Présentation orale en français, support visuel en anglais. À travers des exemples concrets, vous consoliderez vos connaissances et pourrez ainsi réajuster vos habitudes concernant l’utilisation sécurisée de votre boîte e-mail et de votre navigateur Web.

Effect of Media Usage Selection on Social Mobilization Speed: Facebook vs E-Mail.

Science.gov (United States)

Wang, Jing; Madnick, Stuart; Li, Xitong; Alstott, Jeff; Velu, Chander

2015-01-01

Social mobilization is a process that enlists a large number of people to achieve a goal within a limited time, especially through the use of social media. There is increasing interest in understanding the factors that affect the speed of social mobilization. Based on the Langley Knights competition data set, we analyzed the differences in mobilization speed between users of Facebook and e-mail. We include other factors that may influence mobilization speed (gender, age, timing, and homophily of information source) in our model as control variables in order to isolate the effect of such factors. We show that, in this experiment, although more people used e-mail to recruit, the mobilization speed of Facebook users was faster than that of those that used e-mail. We were also able to measure and show that the mobilization speed for Facebook users was on average seven times faster compared to e-mail before controlling for other factors. After controlling for other factors, we show that Facebook users were 1.84 times more likely to register compared to e-mail users in the next period if they have not done so at any point in time. This finding could provide useful insights for future social mobilization efforts.

Effect of Media Usage Selection on Social Mobilization Speed: Facebook vs E-Mail.

Directory of Open Access Journals (Sweden)

Jing Wang

Full Text Available Social mobilization is a process that enlists a large number of people to achieve a goal within a limited time, especially through the use of social media. There is increasing interest in understanding the factors that affect the speed of social mobilization. Based on the Langley Knights competition data set, we analyzed the differences in mobilization speed between users of Facebook and e-mail. We include other factors that may influence mobilization speed (gender, age, timing, and homophily of information source in our model as control variables in order to isolate the effect of such factors. We show that, in this experiment, although more people used e-mail to recruit, the mobilization speed of Facebook users was faster than that of those that used e-mail. We were also able to measure and show that the mobilization speed for Facebook users was on average seven times faster compared to e-mail before controlling for other factors. After controlling for other factors, we show that Facebook users were 1.84 times more likely to register compared to e-mail users in the next period if they have not done so at any point in time. This finding could provide useful insights for future social mobilization efforts.

E-mail marketing grows up: a primer for the managed care industry.

Science.gov (United States)

Dysart, J

2000-02-01

Managed care plans are jumping onto the electronic marketing bandwagon in a big way, taking advantage of not only the basic E-mail system but also expanding on that medium and developing creative vehicles to send the health plan's message. In this article, the author describes how E-mail technology is being used to hone the marketing edge in MCOs.

Factors That Impact Nurses’ Utilization of Electronic Mail (E-Mail).

Science.gov (United States)

1998-05-21

of a system but did little to influence behavior. A study by Golden, Beauclair , & Sussman (1992) surveyed 200 electronic mail account holders at an...Aldine Publishing. Golden, P. A., Beauclair , R., & Sussman, L. (1992). Factors affecting electronic mail use. Computers in Human Behavior, 8, 297-311

Ombuds' corner: Code of Conduct and e-mails

CERN Multimedia

Vincent Vuillemin

2011-01-01

In this series, the Bulletin aims to explain the role of the Ombuds at CERN by presenting practical examples of misunderstandings that could have been resolved by the Ombuds if he had been contacted earlier. Please note that, in all the situations we present, the names are fictitious and used only to improve clarity.   Luke* holds a key position in the coordination of a large project. He is also a recognized expert in modeling complicated structures. Because of his expertise in the field, he receives a considerable number of e-mails every day which he has trouble responding to in addition to his responsibilities of management and development. Constantly interrupted, he tends to answer his emails quickly, sometimes even in an instinctive way, which leads to somewhat laconic messages. One day he receives an e-mail from Dave* challenging some of the decisions taken by the project’s management. Luke agrees with Dave’s remarks, which seem justified given his own expertise of the su...

Suez-Gaz de France merger, E.ON's public takeover bid on Endesa... The new energy fight

International Nuclear Information System (INIS)

Lepetit, V.; Rouaud, P.O.; Mairet, C.

2006-01-01

The energy sector is in fever. In less than a week (February 21 to 26, 2006), the Europe of energy has fallen into a frenzy of mergers and acquisitions: the German E.ON offered 29.1 billion euros to get the Spanish Endesa, Electricite de France (EdF), who already got the Italian Edison in 2005, is ready for more major acquisitions, the Italian Enel is candidate for the repurchasing of Suez, while Gaz de France (GdF) and Suez have started a surprise merger. The stake of this match between giants is their growing up and the penetration of foreign markets before their complete liberalization in July 2007. The potential victims of these actions are the competition and the clients, the industrial ones first. (J.S.)

The style of academic e-mails and conventional letters: contrastive analysis of four conversational routines

Directory of Open Access Journals (Sweden)

Clyde Ancarno

2005-04-01

Full Text Available This paper presents the results of a corpus-based study which investigates the genre of academic email and more specifically its pragmatic dimension. Four conversational routines (thank yous, apologies, requests, offers are analysed and compared in two channels: academic e-mails and conventional print letters. In addition, data from both native and non-native speakers of English is considered, which sheds light on some of the differences found in the academic e-mail writing of learners of English. The findings indicate that academic e-mail is a relatively formal type of correspondence which is still largely influenced, as is to be expected, by the genre of the academic letter, and that as a genre, academic e-mail is in the process of formation or semi-formation. Finally, native speakers of English are found to be more informal than non-native speakers of English in academic e-mails.

Use of F.M.E.A. for reliability analysis of safety systems in nuclear power plants

International Nuclear Information System (INIS)

Barbet, J.F.; Llory, M.; Villemeur, A.

1982-01-01

In the framework of the French nuclear power plant program, reliability studies of safety systems have been carried out at the Electricite de France since 1975. The main results of the studies are examined; about the methodological aspects it appears useful to develop an inductive approach such as the Failure Modes and Effects Analysis (F.M.E.A.). The method is described with its advantages and limitations; the possibilities of use of F.M.E.A. to solve specific safety problems are investigated. To conclude, the future trends of research and development in this field at Electricite de France are pointed out [fr

A Comparative Analysis of E-Mail and Face-to-Face Communication in an Educational Environment

Science.gov (United States)

Lightfoot, Jay M.

2006-01-01

Electronic mail (e-mail) is an extremely important medium for Internet-based education. Due to its unique characteristics, there is reason to be concerned that students do not put appropriate care into writing messages that are sent via e-mail. This has significant implications for the effectiveness of online learning environments. This paper…

Is it too early to move to full electronic PROM data collection?: A randomized controlled trial comparing PROM's after hallux valgus captured by e-mail, traditional mail and telephone.

Science.gov (United States)

Palmen, Leonieke N; Schrier, Joost C M; Scholten, Ruben; Jansen, Justus H W; Koëter, Sander

2016-03-01

Patient reported outcome measures (PROM's) after hallux valgus surgery are used to rate the effectiveness as perceived by the patient. The interpretability of these PROM's is highly dependent on participation rate. Data capture method may be an important factor contributing to the response rate. We investigated the effect on response rate of traditional paper mail, telephone and e-mail PROM's after hallux valgus surgery. All consecutive patients operated between January and September 2013, were identified. Included patients were randomized by envelope in three groups: traditional pen and paper mail, e-mail and telephone. They were asked to fill in a FFI and EQ-5D. Two weeks later non-responders were sent a reminder. Of the 73 included patients, 25 were approached by mail, 24 by e-mail and 24 patients by telephone. The response rate on traditional mail was highest (88%), while response on e-mail was lowest (33%). Response rate on telephone was also high (79%). Response rate on traditional mail and telephone was significantly higher (pmail. Though electronic data collection has enormous potential, this study shows that e-mail yields unacceptable low response rates. It is too early to replace traditional pen-and-paper PROM's by electronic questionnaires. Copyright © 2015 European Foot and Ankle Society. Published by Elsevier Ltd. All rights reserved.

Bragg Gratings, Photosensitivity, and Poling in Glass Fibers and Waveguides: Applications and Fundamentals. Technical Digest Series, Volume 17

Science.gov (United States)

1998-05-26

Figure 2 shows LE spectra in preform B which is composed uniquely by cladding material. The excitation of luminescence has been achieved by...Ge02 concentration, i.e. larger than 20 mol%. Figure 3 shows LE spectra for various luminescence wavelengths collected from preform C. In that...doped fluoride glasses, F. Smektala, R. Sramek, J. Lucas, Laboratoire des Verres et Ceramiques, Universite de Rennes I, 35000 Rennes, France; W. Xie, P

Mapping network development of international new ventures with the use of company e-mails

NARCIS (Netherlands)

Wakkee, I.A.M.

2006-01-01

International new ventures use e-mail frequently to communicate with globally dispersed contacts. In this paper we present and discuss a qualitative research method to map international network development based on company e-mails. Our approach also allows for combinations of inductive and deductive

Shared Semantics and the Use of Organizational Memories for E-Mail Communications.

Science.gov (United States)

Schwartz, David G.

1998-01-01

Examines the use of shared semantics information to link concepts in an organizational memory to e-mail communications. Presents a framework for determining shared semantics based on organizational and personal user profiles. Illustrates how shared semantics are used by the HyperMail system to help link organizational memories (OM) content to…

The Communicative Functions of Emoticons in Workplace E-Mails :-)

DEFF Research Database (Denmark)

Skovholt, Karianne; Grønning, Anette; Kankaanranta, Anne

2014-01-01

CMC research presents emoticons as visual representations of writers' emotions. We argue that the emoticons in authentic workplace e-mails do not primarily indicate writers' emotions. Rather, they provide information about how an utterance is supposed to be interpreted. We show that emoticons...

Mail Office

CERN Multimedia

GS Department

2009-01-01

The Mail Office wishes to remind users that the CERN mail service is exclusively reserved for official CERN mail. All external official mail must be sent to the Mail Office in an unstamped envelope on which your name and Department must be clearly indicated below the official CERN address (see example) to help us to find you in the event that it cannot be delivered. If you wish to send private mail from the CERN site you must use the post offices at Meyrin (63-R-011) or Prévessin (866-R-C02). Please use "PRIORITY" envelopes only in the case of urgent mail. Any mail containing merchandise (i.e. anything other than documents) must be sent using an EDH shipping request form. INTERNAL MAIL Please remember to include the recipient’s MAILBOX number on the internal mail envelopes, either in the relevant box (new envelopes) or next to the name (old envelopes). This information, which can be found in the CERN PHONEBOOK, simplifies our t...

O e-mail como ferramenta de marketing: uma revisão da literatura

OpenAIRE

Fortes, Nuno; Rita, Paulo

2004-01-01

Este artigo, assente exclusivamente em revisão bibliográfica, pretende apresentar as potencialidades do e-mail como uma ferramenta de comunicação de marketing. Em virtude do universo do e-mail marketing estar ensombrado por um crescente fenómeno de spam, são apresentadas duas abordagens alternativas, mas complementares - o marketing de permissão e o marketing viral-, capazes de manterem em níveis elevados os indicadores de eficácia das campanhas.

E-mail security: new restriction on attachments

CERN Multimedia

The Mail Team

2006-01-01

In order to further protect CERN mail users against viruses that spread using malicious files, from 1st March onwards dangerous file types already forbidden as mail attachments will also be forbidden as contents of an archive attachment (.zip and .rar compressed files). More details, including a list of blocked file types, can be found at http://cern.ch/mmmservices/Help/?kbid=171010 The Mail Team

E-mail security: new restriction on attachments

CERN Multimedia

The Mail Team

2006-01-01

In order to further protect CERN mail users against viruses that spread using malicious files, from 1st March onwards dangerous file types already forbidden as mail attachments will also be forbidden as contents of an archive attachment (.zip and .rar compressed files). More details, including a list of blocked file types, can be found at http://cern.ch/mmmservices/Help/?kbid=171010. The Mail Team

Hesitative introduction of E-mail consultations in general practice.

NARCIS (Netherlands)

Verheij, R.; Ton, C.; Tates, K.

2008-01-01

Introduction: The Dutch Council for Public Health and Health Care reported in 2005 that 70% of internet users would want to have the opportunity to consult their own general practitioner by e-mail [1]. Since January 1, 2006, general practitioners in the Netherlands are reimbursed 4.50 euro for

Health Literacy and Global Cognitive Function Predict E-Mail but Not Internet Use in Heart Failure Patients

Directory of Open Access Journals (Sweden)

Jared P. Schprechman

2013-01-01

Full Text Available Background. The internet offers a potential for improving patient knowledge, and e-mail may be used in patient communication with providers. However, barriers to internet and e-mail use, such as low health literacy and cognitive impairment, may prevent patients from using technological resources. Purpose. We investigated whether health literacy, heart failure knowledge, and cognitive function were related to internet and e-mail use in older adults with heart failure (HF. Methods. Older adults (N=119 with heart failure (69.84±9.09 years completed measures of health literacy, heart failure knowledge, cognitive functioning, and internet use in a cross-sectional study. Results. Internet and e-mail use were reported in 78.2% and 71.4% of this sample of patients with HF, respectively. Controlling for age and education, logistic regression analyses indicated that higher health literacy predicted e-mail (P<.05 but not internet use. Global cognitive function predicted e-mail (P<.05 but not internet use. Only 45% used the Internet to obtain information on HF and internet use was not associated with greater HF knowledge. Conclusions. The majority of HF patients use the internet and e-mail, but poor health literacy and cognitive impairment may prevent some patients from accessing these resources. Future studies that examine specific internet and email interventions to increase HF knowledge are needed.

E-mail communication in pain practice: The importance of being earnest.

Science.gov (United States)

Ruiz, Irene Solera; García, Guadalupe Población; Riquelme, Irene

2014-07-01

Information technology can play a vital role in meeting patient needs and reinforcing the relationship among patients and their pain physicians. However, strong resistance remains on the medical side to this type of non-frontal care. The primary objective of this study was to assess the effectiveness of an E-mail intervention on customers' satisfaction. The secondary goals were to analyze the messages from patients to their clinician (not only the volume but also the content) and the impact on client, professional and health services outcomes. A prospective, non-randomized evaluation of patients undergoing treatment for chronic pain from September 2011 to May 2012. A private, specialty referral center in Spain. Participants were users visiting the Pain Management Unit evaluated by one physician. The E-mail address of the facility was written in every medical report provided. Patient satisfaction at the end of the 8-month trial period was assessed and outcomes recorded. Patients reported better communication with their therapist and greater satisfaction with overall care. 780 E-mails were read. Specialists received an average of 5 messages per day (standard deviation 0,3). None of them was unsuitable. This is a prospective, single center evaluation performed by one doctor. There was no control group due to ethical considerations. Electronic communication is a cheap, easy and feasible way to address a wide range of concerns, thus enhancing patients' satisfaction. More efforts are needed to implement routinely usage of this tool. If used appropriately, E-mail can facilitate physician-dependent interactions, promote access to care, save time and reduce costs. Concerns about billing, improper utilization, privacy and confidentiality might complicate its introduction and acceptance. Internet access remains a significant barrier to online patient-provider transference.

E-mail communication in pain practice: The importance of being earnest

Directory of Open Access Journals (Sweden)

Irene Solera Ruiz

2014-01-01

Full Text Available Background: Information technology can play a vital role in meeting patient needs and reinforcing the relationship among patients and their pain physicians. However, strong resistance remains on the medical side to this type of non-frontal care. Objectives: The primary objective of this study was to assess the effectiveness of an E-mail intervention on customers′ satisfaction. The secondary goals were to analyze the messages from patients to their clinician (not only the volume but also the content and the impact on client, professional and health services outcomes. Study Design: A prospective, non-randomized evaluation of patients undergoing treatment for chronic pain from September 2011 to May 2012. Setting: A private, specialty referral center in Spain. Materials and Methods: Participants were users visiting the Pain Management Unit evaluated by one physician. The E-mail address of the facility was written in every medical report provided. Patient satisfaction at the end of the 8-month trial period was assessed and outcomes recorded. Results: Patients reported better communication with their therapist and greater satisfaction with overall care. 780 E-mails were read. Specialists received an average of 5 messages per day (standard deviation 0,3. None of them was unsuitable. Limitations: This is a prospective, single center evaluation performed by one doctor. There was no control group due to ethical considerations. Conclusion s : Electronic communication is a cheap, easy and feasible way to address a wide range of concerns, thus enhancing patients′ satisfaction. More efforts are needed to implement routinely usage of this tool. If used appropriately, E-mail can facilitate physician-dependent interactions, promote access to care, save time and reduce costs. Concerns about billing, improper utilization, privacy and confidentiality might complicate its introduction and acceptance. Internet access remains a significant barrier to online

Changing a Course of Action: Teachers' E-mail Discussion.

Science.gov (United States)

Serafin, Ana Gil

This study examined the e-mail interactions of teachers who were graduate students in an educational leadership program at a commuter university. Participants attended a 3-hour-per-week course. The instructor inserted into the course syllabus an assessment plan that required computer use, making the students responsible for accessing the…

Technical Perspective on Using Information Demand Pattern in a Collaborative Recommendation System for Improving E-Mail Communication

Directory of Open Access Journals (Sweden)

Dirk Stamer

2015-04-01

Full Text Available Today e-mail communication information is widely used in organizations to distribute information. The increasing volume of received e-mails hinders an efficient work. It becomes more and more difficult to identify relevant e-mails inside this enormous volume of information. This work presents a solution in a multi-user environment by improving an established e-mail client extension based on information demand pattern with a recommendation system. The contributions of this work are (1 the concept and implementation of the solution for a single-user environment using information demand pattern, (2 the concept and architecture to use the solution in a multi-user environment (3 a detailed technical description about the proposed solutions.

Behavior change through automated e-mails: mediation analysis of self-help strategy use for depressive symptoms.

Science.gov (United States)

Morgan, Amy J; Mackinnon, Andrew J; Jorm, Anthony F

2013-02-01

To evaluate whether automated e-mails promoting effective self-help strategies for depressive symptoms were effective in changing self-help behavior, and whether this improved depression outcomes. 568 adults with sub-threshold depression participated in a randomized controlled trial and provided complete data. A series of 12 e-mails promoting the use of evidence-based self-help strategies was compared with e-mails providing non-directive depression information. Depression symptoms were assessed with the Patient Health Questionnaire depression scale (PHQ-9) and use of self-help strategies was assessed at baseline and post-intervention. We hypothesized that those receiving the self-help e-mails would increase their use of evidence-based self-help and this would be associated with improvements in depression. Mediation analyses were conducted using a non-parametric bootstrapping procedure. Total use of the self-help strategies promoted in the e-mails significantly mediated the effect of the intervention on depressive symptoms (B = -0.75, SE = 0.16, 95% CI: -1.06 to -0.48). The direct effect of the intervention on depressive symptoms was much smaller and not significant when the mediation path was included. The majority of the individual strategies also had a significant indirect effect on depressive symptoms. In adults with sub-threshold depression, automated e-mails based on behavior change principles can successfully increase use of self-help strategies, leading to a reduction in depressive symptoms. Copyright © 2012 Elsevier Ltd. All rights reserved.

"While you still think, I already type": experienced social power reduces deliberation during e-mail communication.

Science.gov (United States)

Scholl, Annika; Sassenberg, Kai

2014-11-01

E-mail allows individuals to deliberate on their communication before sending it off. For instance, communication partners can easily take their time to ponder how best to frame a request before they actually send a message. Individuals at times strategically exploit this opportunity to deliberate in order to tailor messages to their communication partner, such as when communicating with a relatively more powerful person. As social power reduces concerns about impression management, we predicted that individuals deliberate more while composing e-mail messages under low (vs. high) power. This assumption was tested with well-established power priming. As such, we expected that experienced power in one context would diminish deliberation times during a subsequent e-mail communication. An experiment manipulating the experience of (low vs. high) power and measuring deliberation times during e-mail composition supported this hypothesis. The findings thus indicate how social power alters deliberation times. More importantly, the results show that individuals not only strategically deliberate during e-mail communication in line with their current situation, but also in line with their social standing in a previous situation (here, their experience of power).

New Secure E-mail System Based on Bio-Chaos Key Generation and Modified AES Algorithm

Science.gov (United States)

Hoomod, Haider K.; Radi, A. M.

2018-05-01

The E-mail messages exchanged between sender’s Mailbox and recipient’s Mailbox over the open systems and insecure Networks. These messages may be vulnerable to eavesdropping and itself poses a real threat to the privacy and data integrity from unauthorized persons. The E-mail Security includes the following properties (Confidentiality, Authentication, Message integrity). We need a safe encryption algorithm to encrypt Email messages such as the algorithm Advanced Encryption Standard (AES) or Data Encryption Standard DES, as well as biometric recognition and chaotic system. The proposed E-mail system security uses modified AES algorithm and uses secret key-bio-chaos that consist of biometric (Fingerprint) and chaotic system (Lu and Lorenz). This modification makes the proposed system more sensitive and random. The execution time for both encryption and decryption of the proposed system is much less from original AES, in addition to being compatible with all Mail Servers.

E-Mail from Professor Enhances Student Motivation and Attitudes

Science.gov (United States)

Legg, Angela M.; Wilson, Janie H.

2009-01-01

Traditionally, professors use the first day of class to build rapport. However, current technology allows professors to contact students prior to the first day of class. This study assessed how the receipt of a welcoming e-mail from a female professor 1 week before the first day of class affected student motivation and attitudes toward the…

MAIL OFFICE Outgoing mail

CERN Multimedia

1999-01-01

The Mail Office once again wishes to remind users that the Organisation's mail service is exclusively reserved for official mail._\tAll outgoing official mail must arrive at the Mail Office unfranked and with the sender's name and Division clearly marked under the Organsation's address (see example below).Private mail must be taken to the Post Offices at Meyrin (63-R-011) or Prévessin (866-R-C02)._\tPlease only use 'PRIORITY' envelopes for mail requiring priority handling. Internal mail_\tPlease do not forget to indicate your correspondent's 'MAILBOX' number on the internal mail envelopes either in the specific box provided (new envelopes) or next to his or her name (old envelopes). This will facilitate and accelerate the handling of your mail. Mailbox numbers can be found on: Macintosh\tin the 'Mailbox' field in 'VIPER'PC\tin the 'Mailbox' field of 'Phone book'Web: http://www.cern.ch/CERN/Phone.htmlin the 'MailBox' fieldonce you have selected your correspondent's name...

Test of the Behavioral Perspective Model in the Context of an E-Mail Marketing Experiment

Science.gov (United States)

Sigurdsson, Valdimar; Menon, R. G. Vishnu; Sigurdarson, Johannes Pall; Kristjansson, Jon Skafti; Foxall, Gordon R.

2013-01-01

An e-mail marketing experiment based on the behavioral perspective model was conducted to investigate consumer choice. Conversion e-mails were sent to two groups from the same marketing database of registered consumers interested in children's books. The experiment was based on A-B-A-C-A and A-C-A-B-A withdrawal designs and consisted of sending B…

The use of electronic mail in biomedical communication.

Science.gov (United States)

Costello, R; Shaw, A; Cheetham, R; Moots, R J

2000-01-01

To determine whether there are statistically significant differences in the content of electronic mail (e-mail) and conventional mail sent to authors of papers published in medical journals. Prospective study by postal questionnaire. Over two one-month periods, corresponding authors of papers published in medical journals were asked to record details of the correspondence prompted by their publications. Conventional and e-mail correspondence received. Reprint requests. Content of correspondence. Quality of correspondence. Eighty-two of 96 authors replied. Fifty received e-mail (mean, 5.7+/-8.8 e-mails per author) and 72 received conventional mail (15.5+/-32.8 letters per author) (p mails and only 53% of correspondence sent by conventional mail (p electronic mail. However, the content of e-mail may be of greater scientific relevance. Electronic mail can be encouraged without fear of diminishing the quality of the communications received.

O impacto do e-mail marketing no processo de decisão do consumidor final

OpenAIRE

Mouro, Ana Catarina Ruas

2015-01-01

Mestrado em Comunicação Cultura e Tecnologias da Informação Esta dissertação recai sobre o tema do E-mail Marketing e sobretudo sobre o impacto que tem junto do consumidor final. Nesta dissertação abordou-se primeiramente o impacto que a internet e o mundo digital teve no marketing. Esta perceção é fundamental para que possamos entender a importância que tem o E-mail Marketing nos dias de hoje e a utilidade que esta ferramenta pode vir a ter se bem utilizada. Foi realizado um estudo ...

No Need for Black Chambers: Testing TLS in the E-mail Ecosystem at Large

OpenAIRE

Mayer, Wilfried; Zauner, Aaron; Schmiedecker, Martin; Huber, Markus

2015-01-01

TLS is the most widely used cryptographic protocol on the Internet. While many recent studies focused on its use in HTTPS, none so far analyzed TLS usage in e-mail related protocols, which often carry highly sensitive information. Since end-to-end encryption mechanisms like PGP are seldomly used, today confidentiality in the e-mail ecosystem is mainly based on the encryption of the transport layer. A well-positioned attacker may be able to intercept plaintext passively and at global scale. In...

Responsiveness to a Prospective Student E-Mail Inquiry by Community Colleges in the Nine Mega-States

Science.gov (United States)

Shadinger, David A.

2014-01-01

This quantitative study investigated e-mail responsiveness by community colleges in the nine mega-states to an inquiry from a prospective student. Noel-Levitz (2006b) reported that prospective students want to receive an e-mail with information about an institution prior to applying for admission. Specifically, high school juniors and seniors want…

Self-esteem, interpersonal risk, and preference for e-mail to face-to-face communication.

Science.gov (United States)

Joinson, Adam N

2004-08-01

The media choices made by high and low self-esteem Internet users were studied using web-based methodology (n = 265). Participants were asked to rank four media (face-to-face, e-mail, letter, and telephone) in order of preference across four different communication scenarios designed to pose an interpersonal risk. The level of interpersonal risk posed by two of the scenarios (asking for a pay rise and asking for a date) were also experimentally manipulated by randomly allocating participants to a 25%, 50%, or 75% chance of rejection. Low self-esteem users (LSE) showed a significant preference toward e-mail communication compared to high self-esteem users (HSE). This pattern was reversed for face-to-face preferences. Similarly, a greater chance of rejection in a scenario led to e-mail being preferred to face-to-face communication. The results are discussed in light of both the strategic use of different media and the motivated Internet user.

Comparison of e-mail communication skills among first- and fourth-year dental students.

Science.gov (United States)

Oakley, Marnie; Horvath, Zsuzsa; Weinberg, Seth M; Bhatt, Jaya; Spallek, Heiko

2013-11-01

As e-mail and other forms of electronic communication increase in popularity, it is important for dental schools to consider a curriculum that prepares their graduates to understand and apply effective electronic communication strategies to their patients. Reflecting this shift in communication behavior, the American Medical Association has developed specific e-mail communication guidelines. Some behavioral examples in these guidelines include protecting patients' protected health information (PHI), ensuring proper record keeping, and using professional, courteous, and understandable language. In this study, a sample of first- and fourth-year dental students (n=160) at the University of Pittsburgh School of Dental Medicine participated in an assignment assessing their patient-provider e-mail communication skills. A rubric was used to evaluate and compare the data between dental student classes. The results reveal a generalized lack of compliance with several of these guidelines by both classes (e.g., failure to protect PHI), despite efforts to expose students to these concepts in the curriculum. In an effort to train emerging dentists to function in a rapidly changing technological environment, these findings suggest a need for growth and development of curricula and perhaps guidelines/recommendations for behavioral competencies regarding dental students' use of electronic communication in the patient care environment.

Providing cell phone numbers and e-mail addresses to patients: The patient’s perspective, a cross sectional study

Science.gov (United States)

2012-01-01

Background Today patients can consult with their treating physician by cell phone or e-mail. These means of communication enhance the quality of medical care and increase patient satisfaction, but they can also impinge on physicians’ free time and their patient schedule while at work. The objective of this study is to assess the attitudes and practice of patients on obtaining the cell phone number or e-mail address of their physician for the purpose of medical consultation. Methods Personal interviews with patients, 18 years of age or above, selected by random sampling from the roster of adults insured by Clalit Health Services, Southern Division. The total response rate was 41%. The questionnaire included questions on the attitude and practice of patients towards obtaining their physician’s cell phone number or e-mail address. Comparisons were performed using Chi-square tests to analyze statistically significant differences of categorical variables. Two-tailed p values less than 0.05 were considered statistically significant, with a power of 0.8. Results The study sample included 200 patients with a mean age of 46.6 ± 17.1, of whom 110 were women (55%). Ninety-three (46.5%) responded that they would be very interested in obtaining their physician’s cell phone number, and an additional 83 (41.5%) would not object to obtaining it. Of the 171 patients (85.5%) who had e-mail addresses, 25 (14.6%) said they would be very interested in obtaining their physician’s e-mail address, 85 (49.7%) said they would not object to getting it, and 61 (35.7%) were not interested. In practice only one patient had requested the physician’s e-mail address and none actually had it. Conclusions Patients favored cell phones over e-mail for consulting with their treating physicians. With new technologies such as cell phones and e-mail in common use, it is important to determine how they can be best used and how they should be integrated into the flow of clinical practice

Providing cell phone numbers and e-mail addresses to patients: The patient’s perspective, a cross sectional study

Directory of Open Access Journals (Sweden)

Peleg Roni

2012-08-01

Full Text Available Abstract Background Today patients can consult with their treating physician by cell phone or e-mail. These means of communication enhance the quality of medical care and increase patient satisfaction, but they can also impinge on physicians’ free time and their patient schedule while at work. The objective of this study is to assess the attitudes and practice of patients on obtaining the cell phone number or e-mail address of their physician for the purpose of medical consultation. Methods Personal interviews with patients, 18 years of age or above, selected by random sampling from the roster of adults insured by Clalit Health Services, Southern Division. The total response rate was 41%. The questionnaire included questions on the attitude and practice of patients towards obtaining their physician’s cell phone number or e-mail address. Comparisons were performed using Chi-square tests to analyze statistically significant differences of categorical variables. Two-tailed p values less than 0.05 were considered statistically significant, with a power of 0.8. Results The study sample included 200 patients with a mean age of 46.6 ± 17.1, of whom 110 were women (55%. Ninety-three (46.5% responded that they would be very interested in obtaining their physician’s cell phone number, and an additional 83 (41.5% would not object to obtaining it. Of the 171 patients (85.5% who had e-mail addresses, 25 (14.6% said they would be very interested in obtaining their physician’s e-mail address, 85 (49.7% said they would not object to getting it, and 61 (35.7% were not interested. In practice only one patient had requested the physician’s e-mail address and none actually had it. Conclusions Patients favored cell phones over e-mail for consulting with their treating physicians. With new technologies such as cell phones and e-mail in common use, it is important to determine how they can be best used and how they should be integrated into the flow

Changes in the e-mail policy for people without CERN affiliation

CERN Multimedia

2012-01-01

When affiliated with CERN, every computing account owner is entitled to have a CERN mail address (e.g. “John.Doe@cern.ch”). However, up to now, this mail address was still valid even after the end of a person's affiliation if the owner declared an external email address (e.g. “John.Doe@gmail.com”) to which all personal CERN emails (i.e. those sent to “John.Doe@cern.ch”) could be forwarded.*   As a result, to use our John Doe analogy, John could continue to write and receive emails ostensibly on behalf of CERN despite the fact that he is no longer a member of the personnel or subject to the CERN Staff Rules and Regulations and the Computing Rules. It is doubtful whether this makes sense. Therefore, in agreement with departments and LHC experiments at the last ITSRM meeting, all CERN email addresses of people whose affiliation has been terminated more than six months ago will be deactivated on 15 October 2012. For all others, incl...

Kurumsal Bilgi Kaynağı Olarak E-posta Yönetim Sistemleri = E-mail Management Systems as an Enterprise Information Resource

Directory of Open Access Journals (Sweden)

Külcü, Özgür

2012-01-01

Full Text Available Çalışmada, e-posta kullanımı ve yönetimine ilişkin uluslararası koşullar incelenmekte, bu çerçevede Türkiye’de 28 kurum örneğinde gerçekleştirilen anket verileri değerlendirilmektedir. Betimleme yönteminin kullanıldığı çalışmada literatür incelemesi ve anket tekniklerine dayanarak gerekli veriler elde edilmiştir. Araştırmada e-posta kullanımına ilişkin elde edilen verilerin, ilgili alanda sistemler geliştirmeye çalışan araştırmacılara yardımcı olması beklenmektedir. Kurumsal e-posta yönetimine ilişkin temel sorunlar arasında mesajların üretimi, düzenlenmesi, ayıklanması ve uzun süre korunmasını içeren e-posta yönetim sistemlerinin geliştirilmesi yer almaktadır. Ayrıca insan kaynakları, mali ve idari konuların yönetimi ile belge ve arşiv yönetimi çalışmalarını kapsamına alan, içerisine e-posta yönetiminin de dâhil olduğu sistemlerin bütünleştirilmesi güncel araştırma konuları arasındadır. / This study examines the universal usage and management of e-mail communication and compares with the data, gathered from 28 Turkish institutions. This is a descriptive research in nature and the quantitative data were collected through surveys. It is expected that the results one-mail communication and its usage styles will shed a ligth into researcher who are working on system development. One of the basic problems of organizational e-mail management systems are lack of e-mail systems including message creation, maintenance, disposition, and long term preservation. Furthermore, the results indicate that integration of human resources management, financial and administrative management systems and archival management systems with e-mail managment system is another major problem.

An explanatory study of the use of e-mail investor communication by South African listed companies

Directory of Open Access Journals (Sweden)

Roelof Baard

2016-12-01

Objectives: The objectives of the study were to measure the responsiveness, timeliness and relevance of companies’ responses to e-mail requests, and to test for the determinants (size, market-to-book ratio, profitability, leverage and liquidity thereof. Method: The mystery investor approach and a content analysis were used to study the e-mail handling performance of companies. The associations between company-specific characteristics were statistically tested. Results: It was found that the e-mail handling performance of companies in this study was poor compared with previous studies. Significant relationships between company size and responsiveness and relevance, and between market-to-book ratio and relevance were reported, as well as between the contact method used to request information and relevance and the use of social media and timeliness. Conclusion: Specific areas where companies could improve their investor communications were identified. The need for further research was discussed to explain some of the relationships found, as well as those not found, in contrast to what was expected. Future research is warranted to examine the relationship between the e-mail handling performance of companies and information asymmetry and the cost of equity of companies.

E-mail support as an adjunct to cognitive-behavioral group therapy for social anxiety disorder: Impact on dropout and outcome.

Science.gov (United States)

Delsignore, Aba; Rufer, Michael; Emmerich, Juliane; Weidt, Steffi; Brühl, Annette Beatrix; Moergeli, Hanspeter

2016-10-30

The present study evaluates the impact of semi-individualized e-mail support as an adjunct to cognitive behavioral group therapy (CBGT) for social anxiety disorder (SAD) on dropout and outcome. The effectiveness of additional semi-individualized e-mail support was evaluated for the whole sample and for a subsample of patients at risk of dropping out of therapy. A total of 91 patients with SAD were allocated either to the intervention condition (CBGT with e-mail support), or to the control condition (CBGT without e-mail support). Anxiety symptoms, depression, global symptomatology and life satisfaction were assessed at pretreatment, post-treatment and follow-up (3, 6 and 12 months). From pre-treatment to post-treatment, both groups improved significantly on all symptom measures. Therapy gains were maintained at the 1-year follow-up. Subsample analyses showed that CBGT+e-mail was more effective than CGBT alone in reducing symptom severity among patients missing at least two therapy sessions. Additionally, in this subgroup, those receiving additional e-mail support showed a tendency towards lower dropout rates. Based on the results of this study, semi-individualized e-mail support between sessions seems to enhance the effectiveness of CBGT for SAD patients at risk of dropping out of treatment and should be considered as an additional tool in clinical practice. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

INVESTIGATION OF E-MAIL TRAFFIC BY USING ZERO-INFLATED REGRESSION MODELS

Directory of Open Access Journals (Sweden)

Yılmaz KAYA

2012-06-01

Full Text Available Based on count data obtained with a value of zero may be greater than anticipated. These types of data sets should be used to analyze by regression methods taking into account zero values. Zero- Inflated Poisson (ZIP, Zero-Inflated negative binomial (ZINB, Poisson Hurdle (PH, negative binomial Hurdle (NBH are more common approaches in modeling more zero value possessing dependent variables than expected. In the present study, the e-mail traffic of Yüzüncü Yıl University in 2009 spring semester was investigated. ZIP and ZINB, PH and NBH regression methods were applied on the data set because more zeros counting (78.9% were found in data set than expected. ZINB and NBH regression considered zero dispersion and overdispersion were found to be more accurate results due to overdispersion and zero dispersion in sending e-mail. ZINB is determined to be best model accordingto Vuong statistics and information criteria.

Potential Limitations of E-mail and Text Messaging in Improving Adherence in Glaucoma and Ocular Hypertension.

Science.gov (United States)

Saeedi, Osamah J; Luzuriaga, Christine; Ellish, Nancy; Robin, Alan

2015-01-01

To determine how receptive patients are to the use of e-mail and text message reminders for appointments and medications. We conducted a consecutive cross-sectional survey of eligible patients with glaucoma or ocular hypertension at a private glaucoma subspecialty practice with 3 locations from February 2011 to January 2012. Main outcome measures were answers to survey questions regarding how receptive patients are to e-mail and text messaging reminders for appointments and medications. Of 989 patients, 404 (40.8%) patients reported that e-mail reminders would help remember appointments and 185 (18.7%) reported that they would help for medications. Among those with access to text messaging, 280 (68.9%) reported text messaging would help them remember appointments and 193 (47.5%) reported it would help with medications. Patients who reported e-mail would help them remember medications were more likely to live in an urban location [P=0.05, odds ratio (OR)=1.84], check the internet at least daily (P≤0.001, OR=1.04), check e-mail when not at home or the office (P=0.02, OR=1.62), and know how to open attachments (P=0.03, OR=1.87). Patients who reported that text messaging would help them remember their medications were more likely to be 40 or less (P≤0.001, OR=8.54) and African American (Ptext messaging reminders currently may have a limited utility in improving adherence in the general glaucoma population but may be useful in younger patients with glaucoma.

Computer-Mediated Communication in Psychology Teaching: Influence of Cultural Background on E-Mail Content and on Appraisal

Science.gov (United States)

Hansen, Miriam; Jucks, Regina

2014-01-01

A significant amount of communication between lecturers and students takes place via e-mail. This study provides evidence that two types of cultural cues contained in the e-mail impacts lecturers' linguistic adaptation to, and appraisal of, the student. A total of 186 psychology lecturers from universities in Germany answered a fictitious…

Faculty and Student Expectations and Perceptions of E-mail Communication in a Campus and Distance Doctor of Pharmacy Program

Science.gov (United States)

Turner, Paul D.; Monaghan, Michael S.; Walters, Ryan W.; Merkel, Jennifer J.; Lipschultz, Jeremy H.; Lenz, Thomas L.

2010-01-01

Objective To examine faculty members' and students' expectations and perceptions of e-mail communication in a dual pathway pharmacy program. Methods Three parallel survey instruments were administered to campus students, distance students, and faculty members, respectively. Focus groups with students and faculty were conducted. Results Faculty members perceived themselves as more accessible and approachable by e-mail than either group of students did. Campus students expected a shorter faculty response time to e-mail and for faculty members to be more available than did distance students. Conclusion E-mail is an effective means of computer-mediated communication between faculty members and students and can be used to promote a sense of community and inclusiveness (ie, immediacy), especially with distant students. PMID:21436932

The Role of E-Mail Communications in Determining Response Rates and Mode of Participation in a Mixed-Mode Design

Science.gov (United States)

Cernat, Alexandru; Lynn, Peter

2018-01-01

This article is concerned with the extent to which the propensity to participate in a web face-to-face sequential mixed-mode survey is influenced by the ability to communicate with sample members by e-mail in addition to mail. Researchers may be able to collect e-mail addresses for sample members and to use them subsequently to send survey…

Internet/E-Mail Usage and Well-Being among 65-84 Year Olds in New Zealand: Policy Implications

Science.gov (United States)

Koopman-Boyden, Peggy G.; Reid, Sarah L.

2009-01-01

Research indicates that significant groups of older people are using Internet/e-mail technology. Using data from a 2007 random sample of 1,680 New Zealanders aged 65-84, predictors of Internet/e-mail usage and the impact of usage on well-being were investigated. Gender, age, education, household composition, income, and work were significant…

Colbert's shadow: trade liberalisation and France's energy giants

International Nuclear Information System (INIS)

Anon.

1999-01-01

The slow pace of liberalisation in France's state-owned Electricite de France (EdF) and Gaz de France (GdF) companies are examined, and complaints from the British, Austrian, and Spanish power companies that France has failed to implement the EU directives while EdF has not been slow to expand overseas are considered. The climate of change in France illustrated by the hostile takeover battles, and suspicion of spot and futures trading as speculation rather than offsetting risks are noted. (UK)

[Mobile-phone e-mail use, social networks, and loneliness among Japanese high school students].

Science.gov (United States)

Ogata, Yasuko; Izumi, Yukiko; Kitaike, Tadashi

2006-07-01

The purposes of this study were to assess the loneliness of Japanese high school students who own and use a mobile phone, to clarify the relationships between students' loneliness and their social network and frequency of use of e-mail feature, and to demonstrate relationships with a student's social network and recognition of the benefits and drawbacks of mobile phone use. The participants were 227 students from two classes in each grade of a high school in the Kanto region of Japan. Participants answered a questionnaire covering the UCLA Loneliness Scale as well as questions pertaining to the circumstances of use of their mobile phones, their social networks (e.g., number of friends), and their perceptions of the benefits and drawbacks of mobile phone use. The questionnaires of students owning a mobile phone were analyzed. Total scores for the UCLA Loneliness Scale were calculated, and factor analysis was performed for the benefits and drawbacks. A total of 220 questionnaires were returned, for which 94.1 percent of respondents owned a mobile phone. The percentages of male and female respondents were 58% and 42%. Chronbach's alpha for the UCLA Loneliness Scale (total score) was 0.87, a result similar to previous studies with high school and university students. Factor analysis revealed five factors associated with the benefits and drawbacks of mobile phone use. Multiple-regression analysis showed that 42.9% of the variance in "frequency of e-mail use" was explained by grade level, frequency of mobile phone use, and two of the five factors from the benefits and drawbacks ("difficulty of communication," and "possible sleep loss due to nighttime e-mailing"). Stepwise multiple-regression analysis revealed that 24.4% of the variance in UCLA Loneliness Score was explained by gender, the frequency of e-mail use, the number of friends and the presence/absence of a girlfriend or boyfriend. Presence of an active social network and frequent e-mailing by mobile phone reduced

E-mail support as an adjunct to cognitive-behavioral group therapy for social anxiety disorder: Impact on dropout and outcome

OpenAIRE

Delsignore, Aba; Rufer, Michael; Emmerich, Juliane; Weidt, Steffi; Brühl, Annette Beatrix; Moergeli, Hanspeter

2016-01-01

The present study evaluates the impact of semi-individualized e-mail support as an adjunct to cognitive behavioral group therapy (CBGT) for social anxiety disorder (SAD) on dropout and outcome. The effectiveness of additional semi-individualized e-mail support was evaluated for the whole sample and for a subsample of patients at risk of dropping out of therapy. A total of 91 patients with SAD were allocated either to the intervention condition (CBGT with e-mail support), or to the control con...

E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription

DEFF Research Database (Denmark)

Cartwright, P; Müller, H; Wagener, C

1998-01-01

with E2Fs 1-5, especially within the DNA binding, heterodimerization and marked box domains. Unlike E2Fs 1-5, E2F-6 lacks a transactivation and a pocket protein binding domain, hence, forms a unique third group within the E2F family. E2F-6 is a nuclear protein that can form heterodimers with the DP......The E2F family of transcription factors are essential for the regulation of genes required for appropriate progression through the cell cycle. Five members of the E2F family have been previously reported, namely E2F1-5. All five are key elements in transcriptional regulation of essential genes......, and they can be divided into two functional groups, those that induce S-phase progression when overexpressed in quiescent cells (E2Fs 1-3), and those that do not (E2Fs 4-5). Here, we describe the identification of a novel member of this family, which we refer to as E2F-6. E2F-6 shares significant homology...

Hydrothermal alteration studies of gabbros from northern central Indian ridge and their geodynamic implications

Digital Repository Service at National Institute of Oceanography (India)

Ray, Dwijesh; Mevel, C.; Banerjee, R.

, IPGP, 4 Place Jussieu, F-75252 Paris Cedex 5, France. 3 National Institute of Oceanography, Goa 403 004, India. ∗ e-mail: dwijesh@rediffmail.com Mylonitic gabbro and altered gabbro were recovered from off-axis high and corner high loca- tions at ridge... microprobe analyzer at the CAMPARIS service of the IPG-Paris (University of Paris 6, France). Analytical conditions used were 15 kV accelerating voltage, 20 nA beam current and 20–40 s count- ing times. All analyses were performed in a point mode. A 2–3 µm...

The relationship between the external environment and physician e-mail communication: The mediating role of health information technology availability.

Science.gov (United States)

Mazurenko, Olena; Hearld, Larry R; Menachemi, Nir

Physician e-mail communication, with patients and other providers, is one of the cornerstones of effective care coordination but varies significantly across physicians. A physician's external environment may contribute to such variations by enabling or constraining a physician's ability to adopt innovations such as health information technology (HIT) that can be used to support e-mail communication. The aim of the study was to examine whether the relationship of the external environment and physician e-mail communication with patients and other providers is mediated by the practice's HIT availability. The data were obtained from the Health Tracking Physician Survey (2008) and the Area Resource File (2008). Cross-sectional multivariable subgroup path analysis was used to investigate the mediating role of HIT availability across 2,850 U.S. physicians. Solo physicians' perceptions about malpractice were associated with 0.97 lower odds (p communication with patients and other providers, as compared to group and hospital practices, even when mediated by HIT availability. Subgroup analyses indicated that different types of practices are responsive to the different dimensions of the external environment. Specifically, solo practitioners were more responsive to the availability of resources in their environment, with per capita income associated with lower likelihood of physician e-mail communication (OR = 0.99, p information technology availability, which in turn was associated with a greater likelihood of communicating via e-mail with patients (OR = 1.02, p communication and the external environment is mediated by the practice's HIT availability. Efforts to improve physician e-mail communication and HIT adoption may need to reflect the varied perceptions of different types of practices.

Additional mailing phase for FIT after a medical offer phase: The best way to improve compliance with colorectal cancer screening in France.

Science.gov (United States)

Piette, Christine; Durand, Gérard; Bretagne, Jean-François; Faivre, Jean

2017-03-01

Compliance with colorectal cancer screening is critical to its effectiveness. The organisation of the mass screening programme in France has recently been modified with no evaluation of the consequences. To evaluate the impact of the way the screening test is delivered on compliance. During the first six months of the screening campaign (Ille-Vilaine, Brittany), general practitioners were asked to propose a faecal immunochemical test (FIT), OC-Sensor, to individuals at average risk for colorectal cancer (n=152,097). A subset of non-participants in the medical phase (n=13,071) was randomly chosen to receive a reminder that included the screening test or a simple postal reminder without the screening test. Compliance was 31% if the screening test was proposed during a medical consultation. In non-participants during the medical phase, it was 45% in those receiving both a reminder and the screening test and 28% amongst those receiving a simple reminder. An estimated overall participation rate of 54% can be expected if non-participants in the medical phase are sent a reminder together with the screening test. In France, a compliance rate above the minimum uptake rate of 45% recommended by European Union experts can be achieved if the FIT is mailed to non-participants after the medical free-offer phase. Copyright © 2016. Published by Elsevier Ltd.

Mail2Print online tutorial

CERN Multimedia

CERN. Geneva

2016-01-01

Mail2print is a feature which allows you to send documents to a printer by mail. This tutorial (text attached to the event page) explains how to use this service. Content owner: Vincent Nicolas Bippus Presenter: Pedro Augusto de Freitas Batista Tell us what you think via e-learning.support at cern.ch More tutorials in the e-learning collection of the CERN Document Server (CDS) https://cds.cern.ch/collection/E-learning%20modules?ln=en All info about the CERN rapid e-learning project is linked from http://twiki.cern.ch/ELearning  

Electronic mail : attitudes, self-efficacy, and effective communication

OpenAIRE

Kandies, Jerry T.

1994-01-01

The purpose of this study was (a) to investigate the functional use of e-mail in a university setting and the relationship of attitudes toward and self-efficacy with email technology, and (b) to evaluate writing effectiveness in an electronic medium. The study also sought to determine if certain personal characteristics could serve as predictor variables for explaining e-mail use, attitudes toward email, and self-efficacy with e-mail technology. The population of inter...

The Use of Electronic Mail in Biomedical Communication

OpenAIRE

Costello, Richard; Shaw, Anthony; Cheetham, Roz; Moots, Robert J.

2000-01-01

Objectives: To determine whether there are statistically significant differences in the content of electronic mail (e-mail) and conventional mail sent to authors of papers published in medical journals.

The Uses of E-mail as a Medium on the Contante Justitie Proceedings on the Courts in Indonesia

Directory of Open Access Journals (Sweden)

Yasser S. Wahab

2015-10-01

Full Text Available This research aims to know how the contante justitie principle may be applied into the enforced legislation in Indonesia, and to investigate the synergy of proceedings by means of e-mail in realizing contante justitie. The research employed in this paper is normative research, using both primary and secondary legal sources. Primary sources obtained from compiling relevant rules on the research concerned, in addition to secondary sources taken from books, court decisions, newspapers, internet materials and others relevant with the issue; that is to oversee the contradictions of humanist and mechanical processes when utilizing the internet e-mail for the court proceedings. The use of internet media e-mail in the correspondence process is expected to cut down the time, cost and potential instability. Thus strongly supports the realization of the principle of contante justitie in court proceedings more effectively and efficiently.

E-mail Communities--A Story of Collaboration between Students in Australia and Indonesia.

Science.gov (United States)

Lelong, Peter; Fearnley-Sander, Mary

1999-01-01

Describes two projects: the first linked teacher-education students in Australia and Indonesia through e-mail and then grew into a link between primary students; the second project was a prize-winning publication by the primary students on the Internet. Gives a list of different materials and guidelines for teachers. (CMK)

AstroMail: Electronic mail for the astrophysics community

Science.gov (United States)

Scherrer, Phillip H.; Bogart, Richard S.

1993-01-01

As part of the NASA Science Internet User Support Services program, NASA Goddard was interested in R&D which could extend the SolarMail system developed by members of the Wilcox Space Observatory at Stanford University to support a larger astrophysics user community. Specific objectives of the R&D effort were to include: a clone of the existing SolarMail system with additional documentation, enabling a parallel mail system to be established by populating the database; a cloned version of SolarMail functioning with a user database similar to that of the High Energy Astrophysics Division (HEAD) of the American Astronomical Society; a report on the status and surveyed usage of SolarMail and its clones into an extendable distributed mail system to serve as the basis for AstroMail, including a draft declaration of policy; a prototype AstroMail system based on the above specifications and including at least SolarMail and one of its clones supporting a set of astronomy user databases as subsets; and a report on the status of the prototype AstroMail with recommendations for future modifications to AstroMail.

A produção escrita do gênero e-mail nos livros didáticos de língua inglesa

Directory of Open Access Journals (Sweden)

Sílvia Mônica Moura Lima

2015-07-01

Full Text Available Resumo: As interações sociais vêm proporcionando novas formas de comunicação impulsionadas pelas novas tecnologias. Gêneros como o e-mail tem nos proporcionados variações criativas na língua, sobretudo em sua escrita (CRYSTAL, 2006. Considerando o livro didático (LD como um gênero do discurso, e refletindo sobre essa conjuntura digital que incidem em nossas interações, objetivamos nesse trabalho analisar as atividades de escrita de e-mails em duas coleções didáticas de inglês para o ensino médio, no intuito de verificar nesses gêneros evidências sobre a relação de seus elementos regularizadores como propósitos, estilos, temas, papeis sociais, estrutura composicional e evento deflagrador, ou seja, propõe-se, em linhas gerais, verificar o comportamento do gênero e-mail nas atividades propostas pelos livros, refletindo sobre suas influências. Para dar sustentação a essa pesquisa, fundamentamo-nos nas leituras de Bakhtin (1997[1979], Miller (2012[1984], Swales (2004, Bazerman(2009, Devitt (2004, Bunzen (2008, dentre outros. Os resultados das analises evidenciaram que as atividades de escrita do e-mail são influenciadas pelos propósitos comunicativos do livro didático, os quais se regularizam em aspectos linguísticos e temáticos, refletindo sobremaneira nos demais elementos como estilos, papeis sociais, estrutura composicional e outros, dessa maneira, pouco espelhando a natureza sociorretórica do e-mail na vida social.

Uptake and adherence of a self-directed internet-based mental health intervention with tailored e-mail reminders in senior high schools in Norway.

Science.gov (United States)

Lillevoll, Kjersti R; Vangberg, Hans Christian B; Griffiths, Kathleen M; Waterloo, Knut; Eisemann, Martin R

2014-01-21

Internet-based cognitive behavioural therapy (ICBT) is a promising approach to the prevention and reduction of depressive symptoms among adolescents. This study aimed to evaluate the feasibility and efficacy of disseminating a self-directed internet-based mental health intervention (MoodGYM) in senior high schools. It also sought to investigate possible effects of tailored and weekly e-mail reminders on initial uptake and adherence to the intervention. A baseline survey was conducted in four senior high schools in two Norwegian municipalities (n = 1337). 52.8% (707/1337) of the students consented to further participation in the trial and were randomly allocated to one of three MoodGYM intervention groups (tailored weekly e-mail reminder (n = 175), standardized weekly e-mail reminder (n = 176 ) or no e-mail reminder (n = 175)) or a waitlist control group (n = 180). We tested for effects of the intervention on depression and self-esteem using multivariate analysis of variance, effects of tailored e-mail and self-reported current need of help on initial uptake of the intervention using logistic regression and the effect of weekly e-mails on adherence using ordinal regression. There was substantial non-participation from the intervention, with only 8.5% (45/527) participants logging on to MoodGYM, and few proceeding beyond the first part of the programme. No significant effect on depression or self-esteem was found among the sample as a whole or among participants with elevated depression scores at baseline. Having a higher average grade in senior high school predicted initial uptake of the intervention, but tailored e-mail and self-reported current need of help did not. Weekly e-mail prompts did not predict adherence. The main reasons for non-use reported were lack of time/forgetting about it and doubt about the usefulness of the program. Overall, disseminating a self-directed internet-based intervention to a school population proved difficult despite steps taken to

Characterization of E2F8, a novel E2F-like cell-cycle regulated repressor of E2F-activated transcription

DEFF Research Database (Denmark)

Christensen, Jesper; Cloos, Paul; Toftegaard, Ulla

2005-01-01

The E2F family of transcription factors are downstream effectors of the retinoblastoma protein, pRB, pathway and are essential for the timely regulation of genes necessary for cell-cycle progression. Here we describe the characterization of human and murine E2F8, a new member of the E2F family...

Resident use of the Internet, e-mail, and personal electronics in the care of surgical patients.

Science.gov (United States)

Plant, Mathew A; Fish, Joel S

2015-01-01

The use of smartphones, e-mail, and the Internet has affected virtually all areas of patient care. Current university and hospital policies concerning the use of devices may be incongruent with day-to-day patient care. The goal was to assess the current usage patterns of the Internet, e-mail, and personal electronics for clinical purposes by surgical residents as well as their communication habits and preferences. Also assessed was residents' knowledge regarding the institutional policies surrounding these issues. Surgical residents (n = 294) at a large teaching institution were surveyed regarding their knowledge of university policies as well as daily use of various communication technologies. Communication preferences were determined using theoretical clinical scenarios. Our survey with a response rate of 54.7% (n = 161) revealed that 93.8% of participants indicated daily Internet use for clinical duties. Most respondents (72%) were either completely unaware of the existence of guidelines for its use or aware but had no familiarity with their content. Use of e-mail for clinical duties was common (85%), and 74% of the respondents rated e-mail as "very important" or "extremely important" for patient care. Everyone who responded had a mobile phone with 98.7% being "smartphones," which the majority (82.9%) stated was "very important" or "extremely important" for patient care. Text messaging was the primary communication method for 57.8% of respondents. The traditional paging system was the primary communication method for only 1.3% of respondents and the preferred method for none. Daily use of technology is the norm among residents; however, knowledge of university guidelines was exceedingly low. Residents need better education regarding current guidelines. Current guidelines do not reflect current clinical practice. Hospitals should consider abandoning the traditional paging system and consider facilitating better use of residents' mobile phones.

New Snail Mail Scanning Service

CERN Multimedia

2012-01-01

Modernisation does not stop at the CERN postal service (GS/PS). “With more and more digitisation and the prevalence of e-mail throughout the site, we were hoping to provide more timely delivery of letters and make further saving in resources”, said Tueri Datta, head of GS/PS.   Instead of the standard delivery to your P.O. box, the CERN postal service will digitally scan all letters and books up to 100 pages on reception. These scans will subsequently be sent via e-mail to the corresponding recipient as PDF (Portable Data Format - you will need to install “Acrobat Reader” on your PC). Express mail will be handled with priority. Users without a valid CERN mailbox can register at mail.scan.service@cern.ch in order to have their letters read to them via the phone line (we are currently investigating whether we can use the voices of the last five DGs).   This service will start on 1st April 2012 on the Meyrin site and will gradually replace th...

Increased demand for E-mail health consultation service: analysis of a Web survey.

Science.gov (United States)

Klinar, Ivana; Balazin, Ana; Basić, Martina; Plantas, Igor; Biskupić, Kresimir

2010-06-01

The aim of the study was to explore characteristics of the users of the Interactive Service "Your Questions" that is based on E-mail health consultations. We wanted to find out what motivated users to use it, were they satisfied with it and what were its impacts on their health behavior. Therefore, we developed a Web survey and invited 2,747 users to take part in it. 919 (33.5%) of users responded. Results showed that the majority of respondents were women (79.1%) and that most hold at least a college degree (52.4%). The Service was mostly used for obtaining information about certain medical symptoms or medical conditions (50.1%), for a second opinion on a diagnosis (18.6%) and for more information about medical treatment (14.4%). In terms of Service features, it was used because of its convenience with regard to time (38.7%) and a sense of privacy (25.7%). Before posting a question to the Service, 93.2% of the respondents searched for health articles on the PLIVAzdravlje portal while 90% of them read the Questions and Answers database. Over half of them (61.8%) posted their question after they already visited their physicians on that particular issue. Nevertheless, 48% of them were encouraged to visit their physicians after they received the answer. The results show an important trend of increased demand for e-mail health consultation and the need for reliable medical information, with one thousand questions submitted to the Service in the observed period of 40 days. If the source of medical information is reliable, as in case of our Service as well as other forms of e-mail health consultations, it can have positive impact on valuable physician-patient communication based on knowledge and mutual understanding.

E-mail survey with an attached Form: an off-line data collection alternative via the internet

Directory of Open Access Journals (Sweden)

Alexandre Reis Graeml

2008-09-01

Full Text Available As people start incorporating the Internet in their daily routine, using its resources to carry out their usual activities, it becomes easier to use the Web's environment also to collect data by means of electronic surveys. This paper reports the use of a quantitative research survey, which used an "intelligent" MS Word form, which was sent through e-mail to industrial manufacturers in the state of Sao Paulo - Brazil. The response speed was much better than usually achieved using the conventional procedure of sending the survey through regular mail. The return rate was satisfactory and the cost was much lower than usually incurred, due to the virtualization of the contact with the respondent. The initiative was so successful that the authors decided to share their experience with the academic community, contributing to the maturing of the e-mail survey methodology. Although the focus of this study was strictly academic, the authors believe that the adopted procedures are also suitable for market research, feedback gathering and other entrepreneurial needs.

The project for virus mails and junk mails

International Nuclear Information System (INIS)

Qi Fazhi; Shou Xuejian

2003-01-01

Along with the application of network, Email is becoming more and more important for people's communication. But like other net work applications, Email is being infracted by Virus Mails and Junk mails. Sendmail and Procmail are used to deal with Virus Mails and Junk mails in this paper. It is effective to prevent the IHCP (Institute of High Energy Physics Academia Sinica) mail server from attacks now

E-Mail Writing: Providing Background Information in the Core of Computer Assisted Instruction

Science.gov (United States)

Nazari, Behzad; Ninknejad, Sahar

2015-01-01

The present study highly supported the effective role of providing background information via email by the teacher to write e-mail by the students in learners' writing ability. A total number of 50 EFL advanced male students aged between 25 and 40 at different branches of Iran Language Institute in Tehran, Tehran. Through the placement test of…

Private mail

CERN Multimedia

GS Unit

2008-01-01

The internal mail service deals exclusively with the Organization’s official mail. Non-official mail with no stamp on the envelope will not be sent. Please write systematically your name and Department beneath CERN’s address so that the Mail Office can notify you in case of doubt. Anyone who has recently mailed goods is requested to call 75353 in order to make arrangements to recover them. Mail Office

E-mail as the Appropriate Method of Communication for the Decision-Maker When Soliciting Advice for an Intellective Decision Task.

Science.gov (United States)

Prahl, Andrew; Dexter, Franklin; Swol, Lyn Van; Braun, Michael T; Epstein, Richard H

2015-09-01

For many problems in operating room and anesthesia group management, there are tasks with optimal decisions, and yet experienced personnel tend to make decisions that are worse or no better than random chance. Such decisions include staff scheduling, case scheduling, moving cases among operating rooms, and choosing patient arrival times. In such settings, operating room management leadership decision-making should typically be autocratic rather than participative. Autocratic-style decision-making calls for managers to solicit and consider feedback from stakeholders in the decision outcome but to make the decision themselves using their expert knowledge and the facts received. For this to be effective, often the manager will obtain expert advice from outside the organization (e.g., health system). In this narrative review, we evaluate the advantages and disadvantages of using prompt asynchronous written communication (i.e., e-mail) as a communication channel for such interaction between a decision-maker (manager) and advisor. A detailed Appendix (Supplemental Digital Content, http://links.lww.com/AA/B72) lists each observational and experimental result. We find that the current ubiquitous role of e-mail for such communication is appropriate. Its benefits include improved time management via asynchronicity, low cognitive load (e.g., relative to Web conferencing), the ability to hide undesirable and irrelevant cues (e.g., physical appearance), the appropriateness of adding desirable cues (e.g., titles and degrees), the opportunity to provide written expression of confidence, and the ability for the advisor to demonstrate the answer for the decision-maker. Given that the manager is e-mailing an advisor whose competence the manager trusts, it is unnecessary to use a richer communication channel to develop trust. Finally, many of the limitations of e-mail can be rectified through training. We expect that decades from now, e-mail (i.e., asynchronous writing) between an

Assessment of the PCDD/F fate from MSWI residue used in road construction in France.

Science.gov (United States)

Badreddine, R; François, D

2009-01-01

MSWI fly ash is susceptible to contain high amount of polychlorinated dibenzo-dioxins and polychlorinated dibenzo-furans. However, the use of MSWI residue for road construction started in France at a period when MSWI Bottom Ash and MSWI fly ash were not separated. From four old road sites, MSWI residue, road soils, reference soils and geo-textiles were sampled and their PCDD/F contents were analyzed. MSWI residue show a great heterogeneity but also high amounts of PCDD/F (14-2960 ng I-TEQ kg(-1)dm). Soils underlying the road show less heterogeneity and PCDD/F contents between 0.57 and 7.23 ng I-TEQ kg(-1)dm, lower than ordinary soils. Moreover, the specific analysis of the 17 toxic PCDD/F congeners (notably the 2,3,7,8-TetraCDD) indicates the very low harmfulness of road soils. The study also allows to assert the relation between the MSWI residue particle size and the PCDD/F content.

E2F6: a member of the E2F family that does not modulate squamous differentiation

International Nuclear Information System (INIS)

Wong, C.F.; Barnes, Liam M.; Smith, Louise; Popa, Claudia; Serewko-Auret, Magdalena M.; Saunders, Nicholas A.

2004-01-01

The inhibition of E2F has been demonstrated to be important in the initiation of squamous differentiation by two independent manners: promotion of growth arrest and the relief of the differentiation-suppressive properties of E2Fs. E2F6 is reported to behave as a transcriptional repressor of the E2F family. In this study, we examined the ability of E2F6 to act as the molecular switch required for E2F inhibition in order for keratinocytes to enter a terminal differentiation programme. Results demonstrated that whilst E2F6 was able to suppress E2F activity in proliferating keratinocytes, it did not modulate squamous differentiation in a differentiated keratinocyte. Furthermore, inhibition of E2F, by overexpressing E2F6, was not sufficient to sensitise either proliferating keratinocytes or the squamous cell carcinoma cell line, KJD-1/SV40, to differentiation-inducing agents. Significantly, although E2F6 could suppress E2F activity in proliferating cells, it could not inhibit proliferation of KJD-1/SV40 cells. These results demonstrate that E2F6 does not contain the domains required for modulation of squamous differentiation and imply isoform-specific functions for individual E2F family members

Pouvoir et sexualité. Le discours féministe sur la prostitution en France (1968-1986.

Directory of Open Access Journals (Sweden)

Damien Simonin

2010-07-01

Full Text Available Cette recherche porte sur les discours sur la prostitution dans la presse féministe, entre 1968 et 1986 en France. Durant cette période, le mouvement féministe est composé de courants conflictuels (courants réformistes et révolutionnaires, différentialistes et universalistes et il porte des discours hétérogènes (informations sur la prostitution, analyses théoriques et politiques, témoignages de prostituées. Pourtant, ces discours s'accordent sur la revendication d'une libération des rapport...

Non-official mail

CERN Multimedia

2006-01-01

The Mail Office wishes to remind users of the mail service that the latter is reserved exclusively for the Organization's official mail. Private mail, even if stamped, does not fall into this category, and any mail of this nature found in the 'Outgoing Mail' or 'Départ Courrier' boxes will no longer be collected or accepted by the Meyrin or Prévessin Mail Offices. The Mail Office declines all responsibility in the event of losses, delays or any other problems arising as a result of private mail being placed in these boxes. Thank you for your understanding. The Mail Office

Diabetes and exocrine pancreatic insufficiency in E2F1/E2F2 double-mutant mice.

Science.gov (United States)

Iglesias, Ainhoa; Murga, Matilde; Laresgoiti, Usua; Skoudy, Anouchka; Bernales, Irantzu; Fullaondo, Asier; Moreno, Bernardino; Lloreta, José; Field, Seth J; Real, Francisco X; Zubiaga, Ana M

2004-05-01

E2F transcription factors are thought to be key regulators of cell growth control. Here we use mutant mouse strains to investigate the function of E2F1 and E2F2 in vivo. E2F1/E2F2 compound-mutant mice develop nonautoimmune insulin-deficient diabetes and exocrine pancreatic dysfunction characterized by endocrine and exocrine cell dysplasia, a reduction in the number and size of acini and islets, and their replacement by ductal structures and adipose tissue. Mutant pancreatic cells exhibit increased rates of DNA replication but also of apoptosis, resulting in severe pancreatic atrophy. The expression of genes involved in DNA replication and cell cycle control was upregulated in the E2F1/E2F2 compound-mutant pancreas, suggesting that their expression is repressed by E2F1/E2F2 activities and that the inappropriate cell cycle found in the mutant pancreas is likely the result of the deregulated expression of these genes. Interestingly, the expression of ductal cell and adipocyte differentiation marker genes was also upregulated, whereas expression of pancreatic cell marker genes were downregulated. These results suggest that E2F1/E2F2 activity negatively controls growth of mature pancreatic cells and is necessary for the maintenance of differentiated pancreatic phenotypes in the adult.

Assessing the Factors Affecting the Amount of E-Mail Spam Delivery in a Public School District

Science.gov (United States)

Yasenchock, David A.

2013-01-01

Eighty to ninety percent of e-mail is considered unsolicited commercial communication, or spam. Not only does spam violate the privacy of users, but it also incurs societal costs associated with time-related losses, serves as a vehicle for cyber-crime, and threatens the success of e-commerce by lowering consumer confidence. This quantitative…

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma.

Science.gov (United States)

Kent, Lindsey N; Bae, Sooin; Tsai, Shih-Yin; Tang, Xing; Srivastava, Arunima; Koivisto, Christopher; Martin, Chelsea K; Ridolfi, Elisa; Miller, Grace C; Zorko, Sarah M; Plevris, Emilia; Hadjiyannis, Yannis; Perez, Miguel; Nolan, Eric; Kladney, Raleigh; Westendorp, Bart; de Bruin, Alain; Fernandez, Soledad; Rosol, Thomas J; Pohar, Kamal S; Pipas, James M; Leone, Gustavo

2017-03-01

Disruption of the retinoblastoma (RB) tumor suppressor pathway, either through genetic mutation of upstream regulatory components or mutation of RB1 itself, is believed to be a required event in cancer. However, genetic alterations in the RB-regulated E2F family of transcription factors are infrequent, casting doubt on a direct role for E2Fs in driving cancer. In this work, a mutation analysis of human cancer revealed subtle but impactful copy number gains in E2F1 and E2F3 in hepatocellular carcinoma (HCC). Using a series of loss- and gain-of-function alleles to dial E2F transcriptional output, we have shown that copy number gains in E2f1 or E2f3b resulted in dosage-dependent spontaneous HCC in mice without the involvement of additional organs. Conversely, germ-line loss of E2f1 or E2f3b, but not E2f3a, protected mice against HCC. Combinatorial mapping of chromatin occupancy and transcriptome profiling identified an E2F1- and E2F3B-driven transcriptional program that was associated with development and progression of HCC. These findings demonstrate a direct and cell-autonomous role for E2F activators in human cancer.

E2F1 is crucial for E2F-dependent apoptosis

DEFF Research Database (Denmark)

Lazzerini Denchi, Eros; Helin, Kristian

2005-01-01

Loss of the retinoblastoma protein, pRB, leads to apoptosis, and several results have suggested that this is dependent on the E2F transcription factors. However, so far, the ability of the different E2F family members to contribute to apoptosis is controversial. Here, we show that ectopic...

76 FR 7114 - International Mail: Mailing Services Price Change

Science.gov (United States)

2011-02-09

... POSTAL SERVICE 39 CFR Part 20 International Mail: Mailing Services Price Change AGENCY: Postal... States Postal Service, International Mail Manual (IMM[supreg]) for Mailing Services. This price change correlates to the Postal Service's January 13, 2011 filing of Docket No. R2011-2, Notice of Price Adjustment...

Self-Help for Depression via E-mail: A Randomised Controlled Trial of Effects on Depression and Self-Help Behaviour.

Directory of Open Access Journals (Sweden)

Amy J Morgan

Full Text Available Self-help or self-management strategies are commonly used to deal with depression, but not all are thought to be helpful. A previous study found that sub-threshold depression symptoms were improved by an e-mail intervention that encouraged the use of evidence-based self-help strategies.To investigate whether these e-mails were effective for adults with a range of depression symptomatology including major depression.The study was a parallel-group randomised controlled trial. Adult participants with any level of depressive symptoms were recruited over the internet from the United Kingdom, Australia, Canada, Ireland, New Zealand and the United States. Participants were randomised to receive a series of e-mails either promoting the use of evidence-based self-help strategies or containing depression information as a control. E-mails were sent automatically twice a week for six weeks. Depression symptoms were assessed with the self-rated Patient Health Questionnaire depression scale (PHQ-9.1736 participants with a wide range of symptom severity were recruited and assigned to active (n = 862 and control (n = 874 groups. However, there was a significant attrition rate, with 66.9% lost to follow-up at post-intervention. Both groups showed large improvements in depression symptoms overall, with no significant difference in improvement at the end of the study (mean difference in improvement 0.35 points, 95% CI: -0.57 to 1.28, d = 0.11, 95% CI: -0.06 to 0.27, although there was a small effect at the study mid-point. Results were similar for the sub-group of participants with major depression. The active group showed small to moderate improvements in self-help behaviour (d = 0.40, 95% CI: 0.23 to 0.56.These results suggest that the e-mails were able to increase participants' use of evidence-based self-help, but that this did not improve depression more than an attention control.NCT01399502.

Novel functions for atypical E2Fs, E2F7 and E2F8, in polyploidization and liver cancer

NARCIS (Netherlands)

Pandit, Shusil Kumar

2014-01-01

Atypical E2F transcription factors, E2F7 and E2F8, function as transcriptional repressors of E2F target genes and are crucial for controlling the cell proliferation. In this thesis, we reveal that these two factors are crucial for liver cell polyploidization, embryonic development and prevention of

Do e-mail alerts of new research increase knowledge translation? A "Nephrology Now" randomized control trial.

Science.gov (United States)

Tanna, Gemini V; Sood, Manish M; Schiff, Jeffrey; Schwartz, Daniel; Naimark, David M

2011-01-01

As the volume of medical literature increases exponentially, maintaining current clinical practice is becoming more difficult. Multiple, Internet-based journal clubs and alert services have recently emerged. The purpose of this study is to determine whether the use of the e-mail alert service, Nephrology Now, increases knowledge translation regarding current nephrology literature. Nephrology Now is a nonprofit, monthly e-mail alert service that highlights clinically relevant articles in nephrology. In 2007-2008, the authors randomized 1,683 subscribers into two different groups receiving select intervention articles, and then they used an online survey to assess both groups on their familiarity with the articles and their acquisition of knowledge. Of the randomized subscribers, 803 (47.7%) completed surveys, and the two groups had a similar number of responses (401 and 402, respectively). The authors noted no differences in baseline characteristics between the two groups. Familiarity increased as a result of the Nephrology Now alerts (0.23 ± 0.087 units on a familiarity scale; 95% confidence interval [CI]: 0.06-0.41; P = .007) especially in physicians (multivariate odds ratio 1.83; P = .0002). No detectable improvement in knowledge occurred (0.03 ± 0.083 units on a knowledge scale; 95% CI: -0.13 to 0.20; P = .687). An e-mail alert service of new literature improved a component of knowledge translation--familiarity--but not knowledge acquisition in a large, randomized, international population.

E2F-5, a new E2F family member that interacts with p130 in vivo

NARCIS (Netherlands)

Hijmans, E.M.; Voorhoeve, P.M.; Beijersbergen, R.L.; Veer, L.J. van 't; Bernards, R.A.

1995-01-01

E2F DNA binding sites are found in a number of genes whose expression is tightly regulated during the cell cycle. The activity of E2F transcription factors is regulated by association with specific repressor molecules that can bind and inhibit the E2F transactivation domain. For E2F-1, E2F-2, and

Endorsement of the New Ecological Paradigm in Systematic and E-Mail Samples of College Students

Science.gov (United States)

Rideout, Bruce E.; Hushen, Katherine; McGinty, Dawn; Perkins, Stephanie; Tate, Jennifer

2005-01-01

As the initial phase of a longitudinal study of environmental perspective in college students, resident student opinion was sampled using the New Ecological Paradigm (NEP) scale administered through systematic alphabetical sampling. Sampling was also carried out by a blanket e-mail distribution of surveys for voluntary response. Results showed…

Identification and Disidentification in Organizational Discourse: A Metaphor Analysis of E-Mail Communication at Enron

Science.gov (United States)

Turnage, Anna K.

2010-01-01

This project is situated within the interpretive tradition in organizational communication research, focusing on organizational discourse. It goes further by bringing the discussion into the 21st century through examining how communication technology--specifically e-mail--plays a role in the linguistic practices that help create, maintain and…

76 FR 46853 - International Business Machines Corporation, ITD Business Unit, Division 7, E-mail and...

Science.gov (United States)

2011-08-03

... DEPARTMENT OF LABOR Employment and Training Administration [TA-W-73,218; TA-W-73,218A] International Business Machines Corporation, ITD Business Unit, Division 7, E-mail and Collaboration Group, Including Workers Off-Site From Various States in the United States Reporting to Armonk, NY; International Business Machines Corporation, Web Strategy...

CORPORATE E-MAIL SERVICE GOOGLE APPS AS AN INSTRUMENT OF ACTIVITY OF ORGANIZATIONAL-EDUCATIONAL UNITS OF THE HIGHER EDUCATIONAL INSTITUTION

Directory of Open Access Journals (Sweden)

Кarpenko А.

2017-03-01

Full Text Available The advantages of usage of cloud technologies, particularly, of Gmail service Google Apps in work of organizational-educational units of higher educational institutions are analyzed in this work. The main accents are put concerning usage of corporate e-mail Gmail service Google Apps, with the help of which informational-analytical support of activity of organizational-educational units of the University is provided. The author of the publication underlines key advantages of Gmail and analyses its opportunities. Main characteristics of corporate e-mail Gmail service Google Apps are described. It is identified that implementation of corporate e-mail Gmail service Google Apps is a part of creation of certain information system, that will ensure united information space of a modern higher educational institution. Effective organization of educational process, that was used by methodist of organizational-educational units (Scientific-methodological centre of research, scientific projects and programs of Borys Grinchenko Kyiv University in the work of corporate mail Gmail service Google Aps is analyzed and presented. It is identified, that creation and improvement of mechanisms of building corporate content with the help of Gmail service Google Apps will allow the collaborators of organizational-educational units of the higher educational institution to plan and organize educational process. Such organization of educational process optimizes the activity of organizational-educational units of higher educational institutions.

France intends to raise electricity exports

International Nuclear Information System (INIS)

Grotelueschen, M.; Boiteux.

1986-01-01

In this interview with the Chairman of the Supervisory Board of Electricite de France (EdF), the promotion of nuclear power in France, the chances on the export sector, and the structure of electric power supply are discussed and compared with the situation in West Germany. (UA) [de

Mail Office

CERN Multimedia

GS Department

2011-01-01

On the occasion of the annual closure of CERN, no mail will be distributed on Wednesday, 21 December 2011 but mail will be collected in the morning. Nevertheless, it will be possible for you to bring your outgoing mail to building 555-R-002 until 12:00 noon.

Performances de reproduction dans l’espèce féline en élevage en France

OpenAIRE

Masson, Marine

2016-01-01

Notre étude a pour objectif d’établir des données de référence aux performances de reproduction des chats de race. Cette thèse s’appuie sur l’analyse d’une base de données issue d’un logiciel d’aide à la gestion des élevages félins (Breeding Management System®, BMS, Royal Canin, Aimargues, France). Les informations ont été récoltées de façon anonyme auprès de 1537 éleveurs et portent sur 9327 périodes de chaleurs de 5415 reproductrices de 45 races différentes, 7293 portées et 28966 chatons. L...

Desempenho de cordeiros Santa Inês puros e cruzas Santa Inês com Texel, Ile de France e Bergamácia Performance of Santa Inês lambs and its crosses with Texel, Ile de France e Bergamacia lambs

Directory of Open Access Journals (Sweden)

Iraides Ferreira Furusho-Garcia

2004-12-01

Full Text Available O trabalho foi desenvolvido com o objetivo de estudar o efeito do sexo dos animais, do grupo genético e do peso de abate no desempenho de animais confinados. Foram utilizados 103 cordeiros, machos e fêmeas, Santa Inês puros (SS e cruzas Santa Inês com Texel (TS, Ile de France (FS e Bergamácia (BS, confinados em gaiolas individuais. Mediram-se a dieta fornecida e as sobras diárias, para cálculo do consumo de matéria seca (MS, energia metabolizável (EM, proteína digestível (PD e fibra em detergente neutro (FDN. Os cordeiros foram abatidos em quatro pesos: 15, 25, 35 e 45 kg de peso vivo. Avaliaram-se o ganho de peso diário (GPD, o número de dias no confinamento (ND, a conversão alimentar (CA e o consumo de MS, PD, EM e FDN, nas três fases de crescimento: 15 a 25 kg (1, 25 a 35 kg (2 e 35 a 45 kg (3. Também foram avaliados as idades de abate (IA, o peso do corpo vazio (PCVZ e rendimento de carcaça (RC. Aos 35 e 45 kg, os cordeiros TS e FS apresentaram IA inferiores e as cordeiras SS, IA superiores. O ND dos cordeiros BS de 35 a 45 kg foi maior que dos TS. Aos 35 e 45 kg, o PCVZ dos cordeiros TS e FS foram menores. Os melhores GPD foram dos cordeiros TS, seguidos do FS e SS. Os consumos de MS, PD, EM e FDN foram semelhantes entre os grupos genéticos, nas fases 1 e 2 de crescimento. Verificou-se que os cordeiros TS tenderam a aumentar o consumo, com o incremento de peso, enquanto os outros grupos tenderam a diminuir. A CA elevou-se com o aumento de peso, com exceção dos machos FS. Os machos não apresentaram diferenças na CA entre os grupos genéticos, entretanto, as fêmeas TS e FS apresentaram valores melhores. Aos 35 e 45 kg, as fêmeas apresentaram maiores RC que os machos. Aos 35 kg, os melhores RC foram dos machos TS.The work was carried out to evaluate the effect of animal sex, genetic group and slaugher weight on fedlot lambs performance. One hundred and three male and female lambs, purebred Santa Inês (SS and crosses

Mail office

CERN Multimedia

2012-01-01

In connection with CERN's annual closure, there will be no mail distributed on Friday 21 December 2012 but mail will be collected in the morning. Nevertheless, it will be possible for you to bring us your mail for it to be delivered until 12:00 noon at building 555-R-002.

Composição físico-química do vinho Cabernet Franc proveniente de videiras conduzidas no sistema lira aberta Physico-chemical composition of Cabernet Franc wine from vineyards conducted in the lyre system

Directory of Open Access Journals (Sweden)

Luciano Manfroi

2006-06-01

Full Text Available O objetivo do trabalho foi avaliar as características físico-químicas do vinho Cabernet Franc proveniente de videiras conduzidas no sistema lira aberta durante o ciclo vegetativo de 1995/1996. O experimento foi realizado em oito vinhedos localizados nos municípios de Bento Gonçalves e Monte Belo do Sul, Estado do Rio Grande do Sul. Os vinhos foram elaborados por microvinificação, com duas repetições para cada vinhedo, os quais foram analisados por processos físico-químicos, espectrofotometria de absorção atômica e cromatografia líquida e gasosa. Os parâmetros das variáveis mais significativas foram os seguintes: álcool 9,65%, acidez total 69 meq L-1, pH 3,46, extrato seco reduzido 16,0 g L-1, K nas cinzas 49,4%, ácido tartárico 33 meq L-1, glicerol 9,3 g L-1, prolina 669 mg L-1, antocianinas 330 mg L-1, taninos 1,19 g L-1, intensidade de cor 0,286, K 1.078 mg L-1, metanol 101,7 mg L-1 e soma dos álcoois superiores 450 mg L-1. Os resultados dos vinhos avaliados foram relativamente similares aos encontrados em vinhos Cabernet Franc da mesma região elaborados com uvas provenientes de videiras conduzidas em latada. Eles evidenciam que o sistema de condução da videira em lira aberta constitui-se como alternativa para a produção de vinho tinto fino na Serra Gaúcha.The objective of the work was to evaluate the physico-chemical characteristics of the Cabernet Franc wine from the 1995/1996 vegetative cycle. It was conducted in eight vineyards in the communes of Bento Gonçalves and Monte Belo do Sul, State of Rio Grande do Sul, Brazil. From each vineyard, two microvinifications were elaborated and wines were analysed by physicochemical, atomic absorption spetrophotometry, and liquid and gas chromatography processes. The parameters of the most significant variables were the following: alcohol 9.65%, total titratable acidity 69 meq L-1, pH 3.46, reduced dry extract 16.0 g L-1, K in the ashes 49.4%, tartaric acid 33 meq L-1

Charbonnages de France. 1998 annual report; Charbonnages de France. Rapport Annuel 1998

Energy Technology Data Exchange (ETDEWEB)

NONE

1998-07-01

This annual report of the Charbonnages de France (CdF) group presents the financial results of the group for 1998: coal market, CdF's financial results (turnover, exploitation result, financial result, debt); power production (Snet, Cerchar, Surschiste, Sidec, and CdF Ingenierie activities); coal industry activities (coal mines, coke factories, coal products, environment); progressive ceasing of coal extraction (safety, manpower, reduction of working time, training, management of abandoned sites, rehabilitation, cleansing); management of industrialization and patrimony. (J.S.)

The Aryl Hydrocarbon Receptor Binds to E2F1 and Inhibits E2F1-induced Apoptosis

Science.gov (United States)

Marlowe, Jennifer L.; Fan, Yunxia; Chang, Xiaoqing; Peng, Li; Knudsen, Erik S.; Xia, Ying

2008-01-01

Cellular stress by DNA damage induces checkpoint kinase-2 (CHK2)-mediated phosphorylation and stabilization of the E2F1 transcription factor, leading to induction of apoptosis by activation of a subset of proapoptotic E2F1 target genes, including Apaf1 and p73. This report characterizes an interaction between the aryl hydrocarbon (Ah) receptor (AHR), a ligand-activated transcription factor, and E2F1 that results in the attenuation of E2F1-mediated apoptosis. In Ahr−/− fibroblasts stably transfected with a doxycycline-regulated AHR expression vector, inhibition of AHR expression causes a significant elevation of oxidative stress, γH2A.X histone phosphorylation, and E2F1-dependent apoptosis, which can be blocked by small interfering RNA-mediated knockdown of E2F1 expression. In contrast, ligand-dependent AHR activation protects these cells from etoposide-induced cell death. In cells expressing both proteins, AHR and E2F1 interact independently of the retinoblastoma protein (RB), because AHR and E2F1 coimmunoprecipitate from extracts of RB-negative cells. Additionally, chromatin immunoprecipitation assays indicate that AHR and E2F1 bind to the Apaf1 promoter at a region containing a consensus E2F1 binding site but no AHR binding sites. AHR activation represses Apaf1 and TAp73 mRNA induction by a constitutively active CHK2 expression vector. Furthermore, AHR overexpression blocks the transcriptional induction of Apaf1 and p73 and the accumulation of sub-G0/G1 cells resulting from ectopic overexpression of E2F1. These results point to a proproliferative, antiapoptotic function of the Ah receptor that likely plays a role in tumor progression. PMID:18524851

76 FR 13063 - Airworthiness Directives; EUROCOPTER FRANCE Model SA330F, SA330G, and SA330J Helicopters

Science.gov (United States)

2011-03-10

... Airworthiness Directives; EUROCOPTER FRANCE Model SA330F, SA330G, and SA330J Helicopters AGENCY: Federal... system and the pedals rocking forward. After investigation, it was determined that the Loctite bond on the ``tall pilot'' stop nut was damaged, most likely due to aging of the adhesive. The nut came loose...

Mailing lists are preferred to newsgroups as teaching tools for undergraduate biology classes.

Science.gov (United States)

Machart, J M; Silverthorn, D U

2000-06-01

Effective communication between instructors and students is a challenge regardless of the instructor-to-student ratio. Instructors of large classes, in particular, have resorted to various forms of Internet communication, such as mailing lists and newsgroups, to supplement class time and office hours. Mailing lists are closed discussions among subscribers who receive and send messages via an electronic mail program (e.g., Eudora). Newsgroups are public discussions to which anyone can gain access and respond via a newsreader program (e.g., Nuntius). Newsgroup messages are posted to a bulletin board that the subscriber must visit to read. Mailing lists and newsgroups share many advantages (convenience, greater anonymity, and speed of communication) and disadvantages (computer access required, impersonal nature, junk mail, and lack of graphics in older programs). However, surveys of both faculty and students in biology indicate that mailing lists are generally favored over newsgroups. Reasons given for mailing list popularity included greater familiarity with the E-mail format and ease of access.

E2F1 and E2F2 induction in response to DNA damage preserves genomic stability in neuronal cells.

Science.gov (United States)

Castillo, Daniela S; Campalans, Anna; Belluscio, Laura M; Carcagno, Abel L; Radicella, J Pablo; Cánepa, Eduardo T; Pregi, Nicolás

2015-01-01

E2F transcription factors regulate a wide range of biological processes, including the cellular response to DNA damage. In the present study, we examined whether E2F family members are transcriptionally induced following treatment with several genotoxic agents, and have a role on the cell DNA damage response. We show a novel mechanism, conserved among diverse species, in which E2F1 and E2F2, the latter specifically in neuronal cells, are transcriptionally induced after DNA damage. This upregulation leads to increased E2F1 and E2F2 protein levels as a consequence of de novo protein synthesis. Ectopic expression of these E2Fs in neuronal cells reduces the level of DNA damage following genotoxic treatment, while ablation of E2F1 and E2F2 leads to the accumulation of DNA lesions and increased apoptotic response. Cell viability and DNA repair capability in response to DNA damage induction are also reduced by the E2F1 and E2F2 deficiencies. Finally, E2F1 and E2F2 accumulate at sites of oxidative and UV-induced DNA damage, and interact with γH2AX DNA repair factor. As previously reported for E2F1, E2F2 promotes Rad51 foci formation, interacts with GCN5 acetyltransferase and induces histone acetylation following genotoxic insult. The results presented here unveil a new mechanism involving E2F1 and E2F2 in the maintenance of genomic stability in response to DNA damage in neuronal cells.

Characterization of Clostridium Baratii Type F Strains Responsible for an Outbreak of Botulism Linked to Beef Meat Consumption in France.

Science.gov (United States)

Mazuet, Christelle; Legeay, Christine; Sautereau, Jean; Bouchier, Christiane; Criscuolo, Alexis; Bouvet, Philippe; Trehard, Hélène; Jourdan Da Silva, Nathalie; Popoff, Michel

2017-02-01

A second botulism outbreak due to Clostridium baratii occurred in France in August 2015 and included three patients who had their meal in a restaurant the same day. We report the characterization of C. baratii isolates including whole genome sequencing (WGS). Four C. baratii isolates collected in August 2015 from the outbreak 2 were analysed for toxin production and typing as well as for genetic characterization. WGS was done using using the NEBNext Ultra DNA Library Prep kit for Illumina (New England Biolabs) and sequenced on MiSeq machine (Illumina) in paired-end reads of 250 bases. The phylogenetic tree was generated based on the UPGMA method with genetic distances computed by using the Kimura two-parameter model. Evolutionary analyses were conducted in Bionumerics (V.6.6 Applied Maths). Three C. baratii isolates for patient's stools and one isolate from meat produced botulinum neurotoxin (BoNT) type F and retained a bont/F7 gene in OrfX cluster. All isolates were identical according to the WGS. However, phylogeny of the core genome showed that the four C. baratii strains were distantly related to that of the previous C. baratii outbreak in France in 2014 and from the other C. baratii strains reported in databanks. The fact that the strains isolated from the patients and meat samples were genetically identical supports that the meat used for the Bolognese sauce was responsible for this second botulism outbreak in France. These isolates were unrelated to that from the first C. baratii outbreak in France in 2014 indicating a distinct source of contamination. WGS provided robust determination of genetic relatedness and information regarding BoNT typing and toxin gene locus genomic localization.

Don’t let your mail leak

CERN Multimedia

Computer Security Team

2012-01-01

At CERN, data privacy is of paramount importance, and we are currently developing a comprehensive data protection policy. For example, your CERN mailbox and your “private” folders on AFS and DFS are considered yours...   You might feel like you have nothing to hide, but we are not only talking about personal e-mail: data privacy also pertains to financial mail (acquisitions, tenders), mail related to HR (contracts, assessments), medical information, etc.  As this is considered “private” even if it is work-related, the data cannot normally be accessed by your supervisor, the AFS/DFS/mail service administrators or even the Computer Security Team. Tight procedures have been established for the rare cases where such access is necessary, and these require the prior approval of the CERN Computer Security Officer or the IT Department Head, the Legal Service and the DG (see here for more details). Data privacy is not only the responsibility of the O...

76 FR 16588 - Combined Mailings of Standard Mail and Periodicals Flats

Science.gov (United States)

2011-03-24

... Standard Mail. These mailings must also be identified as Standard Mail when scheduling dropship... pending permit number), issue date, and advertising percentage. b. A consolidated postage statement...

76 FR 10757 - Combined Mailings of Standard Mail and Periodicals Flats

Science.gov (United States)

2011-02-28

... to Standard Mail. These mailings must also be identified as Standard Mail when scheduling dropship... advertising percentage. b. A consolidated postage statement register and postage statement for each...

Estudo alométrico dos tecidos da carcaça de cordeiros Santa Inês puros ou mestiços com Texel, Ile de France e Bergamácia Allometric study on carcass tissues from purebred Santa Inês lambs or crossbred with Texel, Ile de France and Bergamácia

Directory of Open Access Journals (Sweden)

Iraides Ferreira Furusho Garcia

2009-03-01

Full Text Available Utilizaram-se 103 cordeiros, machos e fêmeas, Santa Inês puros (SS e mestiços com Texel (TS, Ile de France (FS e Bergamácia (BS confinados individualmente e abatidos aos 15, 25, 35 ou 45 kg de peso vivo. Após abate e resfriamento da carcaça, foram separados os cortes comerciais pescoço, costela/fralda, costeleta, lombo, paleta e perna, os quais foram dissecados em músculo, osso e gordura. O crescimento alométrico de cada tecido da meia-carcaça foi avaliado em relação ao peso da carcaça fria e os tecidos da perna, do lombo e da paleta em relação ao peso do corte. O desenvolvimento do músculo na meia-carcaça nos machos Santa Inês, Santa Inês × Texel e Santa Inês × Ile de France e nas fêmeas Santa Inês e Santa Inês × Texel foi semelhante ao do peso vivo vazio (coeficiente alométrico (b = 1, enquanto, nos machos Bergamácia e nas fêmeas Ile de France e Bergamácia, foi precoce (b1 em todos os grupos, com exceção da gordura da paleta nos machos BS, cujo desenvolvimento foi semelhante ao do corte (b=1.This study was conducted using 103 male and female lambs from the following genetic groups: Santa Inês (SS purebred and Santa Inês × Texel (TS, Santa Inês × Ile de France (FS, and Santa Inês × Bergamacia (BS crossbred. The animals were slaughtered at the following body weights: 15, 25, 35 or 45 kg. After slaughter and cooling of the carcasses, the following cuts were made: neck, rib/flank, short ribs, loin, blade, and hind limb. The composition in muscle, bone and fat of cuts and ½ carcass were evaluated. The alometric growth of each tissue of the loin, shoulder and leg in relation to the cut weight, and of each tissue of the ½ carcass in relation to the cold carcass weight, was measured. The allometric growth of muscles in the ½ carcass, for BS males and FS and BS females, was early (b1, except shoulder fat in BS males, with isogonic growth (b=1. The growth rate of shoulder muscles in SS and FS males, SS and TS

UNSOLICITED ELECTRONIC MAIL

CERN Multimedia

Judy RICHARDS

1999-01-01

Since November 1997 we have been actively trying to reduce the amount of unsolicited electronic mail, commonly known as SPAM mail that arrives in CERN mailboxes. Unfortunately this is not an easy job since the spammers are constantly finding new ways of breaking our defences! Today spammers are 'forging' addresses in the headers and envelopes of mail in such a way that it is difficult to distinguish between legitimate mail and spams. An additional problem, that does not directly affect most CERN users but does use CERN resources and affects the reputation of CERN, is caused by the spammers who try to make mail look as if it comes from a CERN machine.They either try to route the mail via a CERN machine or simply forge the mail headers to a CERN address so it will have less chance of being blocked by the recipient's anti-spam defences.Although some anti-spam measures can be automated, for many someone has to look at the system logs and spam reports from users and make a human judgement as to what should be bloc...

Efeito de adição de diferentes sais de cálcio nas características da massa e na elaboração de pão francês

Directory of Open Access Journals (Sweden)

Kajishima Shizuko

2003-01-01

Full Text Available O objetivo deste trabalho foi estudar os efeitos da adição do sulfato de cálcio, carbonato de cálcio e fosfato de cálcio dibásico nas características físicas e reológicas da farinha de trigo e na qualidade de pão francês. Utilizou-se a quantidade de sais de cálcio que correspondesse a 100% da IDR de adulto por 100g de pão. Na farinha foram realizadas análises de cor, teor de glúten, farinografia, alveografia e extensigrafia. O pão francês elaborado foi analisado quanto a seu volume específico e conceito global. O enriquecimento com cálcio melhorou a cor da farinha e os resultados satisfatórios obtidos na reologia das massas e com os pães mostraram que se pode utilizar qualquer uma das três fontes para se elaborar pão enriquecido com cálcio.

76 FR 4820 - New Mailing Standards for Domestic Mailing Services

Science.gov (United States)

2011-01-27

.... The parcels do not bear a GS1-128 or Intelligent Mail package barcode. b. The parcels weigh less than... pieces in a mailing must be paid with the same method unless otherwise authorized by Business Mailer... pieces only if authorized by Business Mailer Support. 2.2 Affixed Postage for Presorted First-Class Mail...

Just-in-Time Evidence-Based E-mail “Reminders” in Home Health Care: Impact on Nurse Practices

Science.gov (United States)

Murtaugh, Christopher M; Pezzin, Liliana E; McDonald, Margaret V; Feldman, Penny H; Peng, Timothy R

2005-01-01

Objective To test the effectiveness of two interventions designed to improve the adoption of evidence-based practices by home health nurses caring for heart failure (HF) patients. Data Sources/Study Setting Information on nurse practices was abstracted from the clinical records of patients admitted between June 2000 and November 2001 to the care of 354 study nurses at a large, urban, nonprofit home care agency. Study Design The study employed a randomized design with nurses assigned to usual care or one of two intervention groups upon identification of an eligible patient. The basic intervention was a one-time e-mail reminder highlighting six HF-specific clinical recommendations. The augmented intervention consisted of the initial e-mail reminder supplemented by provider prompts, patient education material, and clinical nurse specialist outreach. Data Collection At each home health visit provided by a study nurse to an eligible HF patient during the 45-day follow-up period, a structured chart abstraction tool was used to collect information on whether the nurse provided the care practices highlighted in the e-mail reminder. Principal Findings Both the basic and the augmented interventions greatly increased the practice of evidence-based care, according to patient records, in the areas of patient assessment and instructions about HF disease management. While not all results were statistically significant at conventional levels, intervention effects were positive in virtually all cases and effect magnitudes frequently were large. Conclusions The results of this randomized trial strongly support the efficacy of just-in-time evidence-based reminders as a means of changing clinical practice among home health nurses who are geographically dispersed and spend much of their time in the field. PMID:15960694

Ecrivains français de Page classique proposés pour l'enseignement du F.LE. en Espagne aux 18e et 19e siècles

OpenAIRE

Fischer Hubert, Denise

2015-01-01

L'étude de la littérature dans les manuels de FLE est assez tardive. L'accent est surtout mis, aux 17e et 18° siècles, sur les règles de grammaire, de prononciation et aussi sur le «français fonctionnel» (dialogues utiles aux marchands et voyageurs qui se déplacent en France et ont besoin d'une phraséologie courante). A la fin du 18e et au 19e siècle, on commence à penser que la lecture des grands classiques est un point important dans l'étude de la langue. Le grammairien se réfère sans cesse...

Review of 5.5 Years' Experience Using E-mail-Based Telemedicine to Deliver Orthopedic Care to Remote Communities.

Science.gov (United States)

Cota, Adam; Tarchala, Magdalena; Parent-Harvey, Caroline; Engel, Victor; Berry, Greg; Reindl, Rudy; Harvey, Edward J

2017-01-01

The use of e-mail-based telemedicine has been demonstrated as an effective and low-cost way of delivering healthcare to patients in remote areas who have limited access to medical services. We established a novel teleorthopedic service for a catchment area encompassing 972,000 km 2 using a commercial off-the-shelf e-mail application. Before the implementation of this program, patients with acute orthopedic injuries were required to travel by air up to 1,900 km for evaluation by an orthopedic surgeon. In the present study, we examined the patient demographics and consultation characteristics and calculated the cost savings associated with patient travel for this teleorthopedic service. We retrospectively reviewed 1,000 consecutive e-mail-based consults and radiographic images received for new patients with acute orthopedic injuries from January 2008 to June 2013. Seventy-nine consults were excluded due to incomplete documentation, leaving 921 available for analysis. The service records were examined to identify patient demographics, orthopedic diagnosis, the percentage of patients managed locally, and the medical indications for patients requiring transfer. As the travel costs for patients requiring transport to the university hospital center are borne by governmental health agencies, the savings accrued from treating patients in their home communities were also calculated. For the 921 consultations, the mean age of patients was 27 years (range, 3 months-88 years), with 40.7% of all patients being younger than 18 years. The most common diagnoses were ankle fractures (15.2%), clavicle fractures (11.2%), distal radius fractures (11.2%), and fractures of the foot (10.2%). One hundred ninety patients (20.6%) required transfer, whereas 731 patients (79.4%) were treated in their home communities. Of the patients who were transferred, 123 (64.7%) required surgery, 55 (28.9%) required clinical evaluation by an orthopedic surgeon, and 12 (6.4%) required CT or MRI. Cost

32 CFR 806b.29 - Sending personal information over electronic mail.

Science.gov (United States)

2010-07-01

... information over electronic mail. (a) Exercise caution before transmitting personal information over e-mail to... 32 National Defense 6 2010-07-01 2010-07-01 false Sending personal information over electronic mail. 806b.29 Section 806b.29 National Defense Department of Defense (Continued) DEPARTMENT OF THE AIR...

Hauts-de-France. A pioneer in the French energy transition; Hauts-de-France. Vorreiter in der franzoesischen Energiewende

Energy Technology Data Exchange (ETDEWEB)

Falk, Thomas

2016-08-15

France had established in advance of last year's climate summit in Paris on ambitious energy policy goals. Especially the 2016 newly formed Region Hauts-de-France stands out as a pioneer here. There one drives innovation and investments with the objective of fulfilling by 2050 their own needs completely by renewable sources. The orientation to supplies Jeremy Rifkin idea of the third industrial revolution. If successful, the region would be on climate protection well ahead of the national targets, the 2050 ''only'' provide a CO{sub 2} emission reduction of 75%. In addition to the Research and development (R and D) to many future ideas in Hauts-de-France but also some major projects for Security of European energy supplies are realized that show the local agility. [German] Frankreich hatte sich im Vorfeld des letztjaehrigen Pariser-Klimagipfels auf ambitionierte Energiewendeziele festgelegt. Insbesondere die 2016 neu gebildete Region Hauts-de-France sticht dabei als Vorreiter heraus. Dort treibt man Innovationen und Investitionen mit dem Ziel an, bis 2050 den Eigenbedarf vollstaendig mittels erneuerbarer Quellen zu decken. Die Orientierung dazu liefert Jeremy Rifkins Idee der dritten industriellen Revolution. Im Erfolgsfall laege die Region beim Klimaschutz deutlich vor den nationalen Zielen, die bis 2050 ''nur'' eine CO{sub 2}-Emissionsreduktion von 75 % vorsehen. Neben der Forschung und Entwicklung (F and E) zu vielen Zukunftsideen werden in Hauts-de-France aber auch einige Grossprojekte zur Absicherung der europaeischen Energieversorgung realisiert, die Ausweis der dortigen Agilitaet sind.

The Additional Value of an E-Mail to Inform Healthcare Professionals of a Drug Safety Issue: A Randomized Controlled Trial in the Netherlands.

Science.gov (United States)

Piening, Sigrid; de Graeff, Pieter A; Straus, Sabine M J M; Haaijer-Ruskamp, Flora M; Mol, Peter G M

2013-09-01

The usefulness and the impact of Direct Healthcare Professional Communications (DHPCs, or 'Dear Doctor letters') in changing the clinical behaviour of physicians have been debated. Changes in the current risk communication methods should preferably be based on the preferences of the healthcare professionals, to optimize the uptake of the message. The aim of this study was to assess whether safety issues are communicated more effectively with an additional e-mail sent by the Dutch Medicines Evaluation Board (MEB) than with the DHPC only. A randomized controlled trial was conducted amongst ophthalmologists and hospital pharmacists in the Netherlands, who were the target group of a DHPC that was issued for pegaptanib, a drug that is administered intra-ocularly in patients with macular degeneration. The intervention group (N = 110) received the pegaptanib DHPC, as well as the MEB e-mail. The control group (N = 105) received the traditional paper-based DHPC only. Two weeks later, the study population received an invitation to fill out an online questionnaire. Questions were asked about the respondents' knowledge and attitude regarding the pegaptanib issue, and any action they had consequently taken. Additional questions were asked about their satisfaction with the DHPC and the e-mail, and their preferred source of such information. Forty respondents (18.6%) completed the questionnaire. Eighty-one percent of the respondents in the intervention group (N = 21) and 47% of the control group (N = 19) correctly indicated that a serious increase in intra-ocular pressure could be caused by pegaptanib injections (Fishers' exact test, p = 0.046). Nine respondents in the intervention group versus none of the control group respondents indicated that they had taken action in response to the pegaptanib safety issue (Fishers' exact test, p = 0.01). The majority of both the intervention group and the control group confirmed that they would like to receive an MEB e-mail with safety

Gas de France, a major player in Europe

International Nuclear Information System (INIS)

Mandil, C.

1999-01-01

Present in approximately 20 countries, the Gaz de France group has, for several years now, committed itself to a major program for international development. This trend should speed up as the European gas market opens. Nowadays, GdF has nearly twelve million customers, including two million outside France. (author)

A New Method of Viewing Attachment Document of eMail on Various Mobile Devices

Science.gov (United States)

Ko, Heeae; Seo, Changwoo; Lim, Yonghwan

As the computing power of the mobile devices is improving rapidly, many kinds of web services are also available in mobile devices just as Email service. Mobile Mail Service began early, but this service is mostly limited in some specified mobile devices such as Smart Phone. That is a limitation that users have to purchase specified phone to be benefited from Mobile Mail Service. In this paper, it uses DIDL (digital item declaration language) markup type defined in MPEG-21 and MobileGate Server, and solved this problem. DIDL could be converted to other markup types which are displayed by mobile devices. By transforming PC Web Mail contents including attachment document to DIDL markup through MobileGate Server, the Mobile Mail Service could be available for all kinds of mobile devices.

Acidez na vinificação em tinto das uvas Isabel, Cabernet Sauvignon e Cabernet Franc

Directory of Open Access Journals (Sweden)

Rizzon Luiz Antenor

2002-01-01

Full Text Available A acidez é uma das características gustativas mais importantes dos vinhos e influencia sua estabilidade e coloração. Devido à insolubilização do ácido tartárico sob a forma de sais, a acidez titulável e o pH podem ser alterados durante a vinificação de acordo com o teor de potássio da uva. Este trabalho avaliou a evolução da acidez durante a vinificação de três cultivares de uvas tintas (Isabel - Vitis labrusca -, Cabernet Sauvignon e Cabernet Franc - Vitis vinifera da Serra Gaúcha. Os vinhos foram elaborados por microvinificação na safra de 1995, sendo avaliados a evolução da acidez titulável, pH, ácido tartárico e potássio imediatamente após o esmagamento da uva, na descuba e após a fermentação alcoólica, a fermentação malolática e a estabilização tartárica, totalizando análises em cinco fases da vinificação. Os resultados mostraram uma evolução diferente da acidez, avaliados através do pH, da acidez titulável, do ácido tartárico e do potássio, na vinificação em tinto da uva Isabel em relação à Cabernet Sauvignon e à Cabernet Franc, nas fases compreendidas entre o esmagamento da uva e a descuba. O vinho Isabel se caracterizou por apresentar teores mais elevados de acidez titulável e ácido tartárico e mais baixos de potássio e pH, em relação aos vinhos Cabernet Sauvignon e Cabernet Franc.

Analysis list: E2f4 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available E2f4 Blood,Embryonic fibroblast,Liver,Muscle,Pluripotent stem cell + mm9 http://dba...rchive.biosciencedbc.jp/kyushu-u/mm9/target/E2f4.1.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/E2f4....5.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/E2f4.10.tsv http://dbarchive.biosciencedbc....jp/kyushu-u/mm9/colo/E2f4.Blood.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/E2f4....Embryonic_fibroblast.tsv,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/E2f4.Liver.tsv,htt

Training and training simulators for emergency situations in France

International Nuclear Information System (INIS)

Petit, G.

1990-01-01

The aim of this paper is to present principles and means set up by Electricite de France (E.D.F.) to provide the required tailor-made training. Today, recent advantages in computing capacities and software engineering along with the completion of Research and Development Training Division programs in the reactor safety (R+D) field (CATHARE, BETHSY..) give E.D.F. the opportunity to conceive and operate new tools for training which are described in the paper: RTGV-SEPIA: a simulator devoted to self training in SGTR field, thanks to a powerful expert system. SIPA: a 'generator of simulators' aiming at control and engineering studies and training, provided with a software able to give in real time a relevant description of complex topologies with diphasic flow patterns (up to a 12'' break in the primary coolant system of a reactor). (orig./DG) [de

SMS text pre-notification and delivery of reminder e-mails to increase response rates to postal questionnaires in the SUSPEND trial: a factorial design, randomised controlled trial.

Science.gov (United States)

Starr, Kathryn; McPherson, Gladys; Forrest, Mark; Cotton, Seonaidh C

2015-07-08

Patient-reported outcomes are vital in informing randomised controlled trials (RCTs) and health-care interventions and policies from the patient's perspective. However, participant non-response may introduce bias and can affect the generalisability of the trial. This study evaluates two interventions aimed at increasing response rates to postal questionnaires within a large, UK-wide RCT: pre-notification via short messenger service (SMS) text prior to sending the initial mailing of trial questionnaires versus no pre-notification; for non-responders to the initial mailing of the questionnaires, an e-mail reminder (containing a hyperlink to complete the questionnaire online) versus a postal reminder. This study is a 2 × 2 partial factorial design RCT nested within an RCT of medical expulsive therapy for ureteric stone disease. Participants who supplied a mobile telephone number were randomly assigned to receive an SMS text pre-notification of questionnaire delivery or no pre-notification. Those who supplied an e-mail address were randomly assigned to receive a questionnaire reminder by e-mail or post. Participants could be randomly assigned to the pre-notification comparison or the reminder comparison or both. The primary outcome measure was response rate at each questionnaire time point. Four hundred eighteen participants were randomly assigned to the SMS pre-notification comparison (80% were male, and the mean age was 41 years with a standard deviation (SD) of 11.1). The intervention had no effect on response rate at either questionnaire time point. In subgroup analyses, SMS pre-notification increased response rates in women but only at the first questionnaire time point. One hundred nineteen participants were randomly assigned to the reminder comparison (80% were male, and the mean age was 42 years with an SD of 12.1). There was no difference in response rate in those who received an e-mail reminder compared with those who received a postal reminder. SMS text pre

PubMed Informer: Monitoring MEDLINE/PubMed through E-mail Alerts, SMS, PDA downloads and RSS feeds

Science.gov (United States)

Muin, Michael; Fontelo, Paul; Ackerman, Michael

2005-01-01

Summary PubMed Informer is a Web-based monitoring tool for topics of interest from MEDLINE/PubMed primarily designed for healthcare professionals. Five tracking methods are available: Web access, e-mail, Short Message Service (SMS), PDA downloads and RSS feeds. PubMed Informer delivers focused search updates and specific information to users with varying information-seeking practices. PMID:16779344

Analysis of the Spanish-speaking mailing list RADIOLOGIA

International Nuclear Information System (INIS)

Rodriguez-Recio, Francisco Javier; Sendra-Portero, Francisco

2007-01-01

The objective of this study was to analyse the mailing list RADIOLOGIA during its first 5 years of operation (from 1998 to 2003). A survey questionnaire was sent to evaluate the characteristics of subscribers and to score (from 0 to 9) the functionality, usefulness and quality of the mailing list. All messages sent to the list during the evaluated period were classified and quantified. A social network analysis was performed from all messages replied to during 2001 and 2002 with the option 'reply to' included in the subject. One hundred and forty (36.8%) responses were collected from 380 subscribers, mainly radiologists (90.0%). 80% of responders were located in Spain, 16% in Latin America, and 4% in other places. The obtained scores (mean ± standard deviation) were: functionality 7.4 ± 1.3; usefulness 7.0 ± 1.4; and quality of e-mail contents 6.0 ± 1.4. During the evaluated period 2700 e-mail messages were sent to the list, with a monthly distribution of 44.3 ± 26.0. The list functioning has been based on an active minority of subscribers that provided information and responses to the rest of the subscribers, a ring of active members that participated in discussions, and about 50% of passive members

A Cost-Effective Approach for Migrating Enterprise Electronic Mail Systems

Directory of Open Access Journals (Sweden)

Emmanuel Omojokun

2008-02-01

Full Text Available Electronic mail (E-mail is one of the most utilized application software systems in modern-day organizations. The major messaging application programs used in the enterprise are IBM Lotus Notes also known as Domino, Microsoft Exchange Servers, and Novel GroupWise. For various reasons – such as high cost of maintenance, undeliverable e-mail issue and loss of attachments, companies find it necessary to either migrate to newer versions of their messaging software or to an entirely different software. In either case, the process must be carefully planned, well designed and properly implemented to avoid disaster. In this paper, we present a cost-effective approach for migrating a particular messaging software. The approach was implemented and tested for the migration of GroupWise 5.5 to Exchange Server 2003. We present our success story and lessons learned from the case. A six-week and one-year post migration system-audits indicated that the organization derived several benefits including significant cost savings as a result of this particular approach. Chief information/technology officers and e-mail administrators will benefit immensely from the "best practice" strategy hereby presented.

Federal Mail Expenditures

Data.gov (United States)

General Services Administration — Agencies annually report mail data using the Simplified Mail Accountability Reporting Tool (SMART), a web-based reporting tool cosponsored by GSA and the Department...

Analysis list: E2f1 [Chip-atlas[Archive

Lifescience Database Archive (English)

Full Text Available E2f1 Blood,Liver + mm9 http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/E2f1.1....tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/target/E2f1.5.tsv http://dbarchive.biosciencedbc.jp/kyus...hu-u/mm9/target/E2f1.10.tsv http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/E2f1.Blood.tsv,http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/E2f1.Liver.tsv http://dbarchive.bioscience...dbc.jp/kyushu-u/mm9/colo/Blood.gml,http://dbarchive.biosciencedbc.jp/kyushu-u/mm9/colo/Liver.gml ...

E-mail og/eller SMS: 22 husholdningers erfaringer på baggrund af et års feedback om elforbruget

DEFF Research Database (Denmark)

Larsen, Anders

Hovedresultatet er, at husholdningerne værdsætter on-line information (via sms og e-mail) om udviklingen i deres elforbrug. Husholdningerne værdsætter dette uafhængigt af deres holdninger i øvrigt til energibesparelser. Informationen giver husholdningerne en ønsket oplevelse af kontrol. Rapporten...

An Internet treatment with weekly e-mail contacts used in a tobacco unit: clinical utility and predictors of outcome

NARCIS (Netherlands)

Gallego, M.J.; Modesto, M.; Muñoz, M.A.; Almajano, M.J.; Modolell, E.; Peris, C.P.; Emmelkamp, P.M.G.

2014-01-01

This work presents preliminary data on the clinical utility and outcome predictors of The San Francisco Stop Smoking Internet Site (SFSSIS) (Lenert et al., 2003) used with weekly e-mail contacts and the usual pharmacological treatment. Fifty smokers participated in the current series of cases, 24

Charbonnages de France. 1998 annual report

International Nuclear Information System (INIS)

1998-01-01

This annual report of the Charbonnages de France (CdF) group presents the financial results of the group for 1998: coal market, CdF's financial results (turnover, exploitation result, financial result, debt); power production (Snet, Cerchar, Surschiste, Sidec, and CdF Ingenierie activities); coal industry activities (coal mines, coke factories, coal products, environment); progressive ceasing of coal extraction (safety, manpower, reduction of working time, training, management of abandoned sites, rehabilitation, cleansing); management of industrialization and patrimony. (J.S.)

Mail Delivery | 19 December

CERN Multimedia

Mail Office

2014-01-01

Due to the annual closure of CERN, no mail will be distributed on Friday, 19 December but mail will still be collected in the morning. Nevertheless, it will be possible for you to bring outgoing mail to building 555-R-002 until 12 noon.

Electronic Computer Originated Mail Service

Science.gov (United States)

Seto, Takao

Electronic mail originated by computer is exactly a new communication media which is a product of combining traditional mailing with electrical communication. Experimental service of this type of mailing started in June 10, 1985 at Ministry of Posts and Telecommunications. Its location in various communication media, its comparison with facsimile type electronic mailing, and status quo of electronic mailing in foreign countries are described. Then, this mailing is briefed centering around the system organization and the services. Additional services to be executed in near future are also mentioned.

Serviço de orientação via e-mail: novas considerações

Directory of Open Access Journals (Sweden)

Ivelise Fortim

Full Text Available Este artigo se propõe a analisar o aumento crescente da demanda do serviço de orientação psicológica via e-mail, desenvolvido pelo Núcleo de Pesquisa de Psicologia e Informática da Clínica Psicológica Ana Maria Poppovic, da Pontifícia Universidade Católica de São Paulo. Partindo de uma breve retrospectiva dos serviços do núcleo, do perfil dos usuários, dos tipos de pedidos e dos temas centrais das mensagens nos anos 2003 e 2004, este texto apresenta novas reflexões sobre uma área de pesquisa muito proeminente dentro da Psicologia, incluindo elementos atuais às hipóteses anteriormente formuladas. As recentes transformações e atualizações tecnológicas pedem constantes análises, que são necessárias à promoção de qualidade e ética no exercício da profissão mediado pelo computador.

Mail Office annual closure

CERN Multimedia

2013-01-01

On the occasion of the annual closure of CERN, there will be no mail distributed on Friday 20 December 2013 but mail will be collected in the morning. Nevertheless, you will still be able to bring your outgoing mail to Building 555-R-002 until 12 noon.  

Molecular and functional characterisation of E2F-5, a new member of the E2F family

NARCIS (Netherlands)

Buck, V.; Allen, K.E.; Sørensen, T.; Bybee, A.; Hijmans, E.M.; Voorhoeve, P.M.; Bernards, R.A.; Thangue, N.B. La

1995-01-01

The transcription factor DRTF1/E2F is implicated in the control of cellular proliferation due to its interaction with key regulators of cell cycle progression, such as the retinoblastoma tumour suppressor gene product and related pocket proteins, cyclins and cyclin-dependent kinases. DRTF1/E2F DNA

Global surveillance of emerging diseases: the ProMED-mail perspective Vigilância global de doenças emergentes: a perspectiva da ProMED-mail

Directory of Open Access Journals (Sweden)

John P. Woodall

2001-01-01

Full Text Available The Internet is changing the way global disease surveillance is conducted. Countries and international organizations are increasingly placing their outbreak reports on the Internet, which speeds up distribution and therefore prevention and control. The World Health Organization (WHO has recognized the value of nongovernmental organizations and the media in reporting outbreaks, which it then attempts to verify through its country offices. However, WHO and other official sources are constrained in their reporting by the need for bureaucratic clearance. ProMED-mail has no such constraints, and posts outbreak reports 7 days a week. It is moderated by infectious disease specialists who add relevant comments. Thus, ProMED-mail complements official sources and provides early warning of outbreaks. Its network is more than 20,000 people in over 150 countries, who place their computers and time at the network's disposal and report on outbreaks of which they have knowledge. Regions and countries could benefit from adopting the ProMED-mail approach to complement their own disease surveillance systems.A Internet está mudando a condução da vigilância global de doenças. Cada vez mais, os países e as organizações internacionais estão divulgando seus informes na Internet, o que acelera não apenas a distribuição desta informação, como também, consequentemente, a prevenção e controle das doenças. A Organização Mundial da Saúde (OMS já reconheceu a importância das ONGs e da imprensa na notificação de surtos, que procura verificar posteriormente através de suas agências locais. Entretanto, a OMS e outras fontes oficiais sofrem restrições em seus relatórios pela obrigatoriedade da autorização burocrática, além de só publicarem informes nos dias úteis. A ProMED-mail não está sujeita a tais restrições. A rede é moderada por especialistas em doenças infecciosas, que acrescentam comentários relevantes. Assim, a ProMED-mail

Carcaça de borregos Ile de France inteiros ou castrados e Hampshire down castrados abatidos aos doze meses de idade Carcass of intact or castrated Ile de France and castrated Hampshire down lambs slaughtered at twelve months of age

Directory of Open Access Journals (Sweden)

Edson Luis de Azambuja Ribeiro

2001-06-01

Full Text Available Um total de 24 borregos, sendo oito Ile de France inteiros, oito Ile de France castrados e oito Hampshire Down castrados, foram utilizados com o objetivo de avaliar características qualitativas e quantitativas da carcaça. Os animais foram mantidos exclusivamente em pastagem de grama Coast-Cross, sendo abatidos aos 12 meses de idade. As carcaças provenientes de animais inteiros da raça Ile de France apresentaram significativamente maior percentagem de pescoço do que as de animais castrados da mesma raça, sendo essa a única diferença encontrada entre esses dois grupos. Porém, foram observadas diferenças na composição tecidual da paleta entre as raças, sendo que os animais da raça Ile de France (inteiros ou castrados apresentaram maior percentual de músculo e maior relação músculo/osso do que os animais da raça Hampshire Down. Os resultados indicam que, por não haver diferenças importantes entre carcaças e carnes de animais inteiros e castrados abatidos aos 12 meses de idade, o uso da castração pode ser dispensado em sistemas intensivos de produção de carne ovinaA total of 24 lambs, eight intact Ile de France, eight castrated Ile de France and eight castrated Hampshire Down, were used in this experiment with the main objective of evaluating quantitative and qualitative carcass traits. The animals were raised on a Coast-Cross pasture and slaughtered at 12 months of age. Carcasses from intact Ile de France lambs had significantly more neck than carcasses from castrated Ile de France lambs. No other differences were observed between carcasses from intact or castrated Ile de France. However, differences between breeds were observed for tissue composition of the shoulder. Shoulders from Ile de France carcasses (intact or castrated presented greater percentage of muscles and greater relation of muscles/bones than shoulders from Hampshire Down lambs. Results indicate that intact males can be recommended for sheep meat production

Politeness Accommodation in E-Mail Requests among Iranian Postgraduate Students of EFL

Directory of Open Access Journals (Sweden)

Muhammed Parviz

2012-11-01

Full Text Available Computer-mediated communication (CMC offers us a chance to understand how social relationships are built and maintained in an environment in which interlocutors not only lack the paralinguistic features that are vital to face-to- face conversation, but are participating in a medium which has had little time to develop rules of conduct. The present study was an attempt to determine politeness accommodation in e-mail messages among Iranian postgraduate students of EFL. One hundred EFL learners, aged 22-26, participated in this study. Four different message types were constructed and sent to the participants, i.e. messages with verbal politeness markers; messages with structural politeness elements (e. g., salutation and closing remarks; messages with both verbal and structural politeness indicators; finally messages with neither verbal nor structural politeness indicators. Further, the messages varied in their degree of politeness; however, their content was the same. Results showed that the participants accommodated significantly to verbal politeness indicators in the body of a message, and to structural politeness indicators of greeting/salutation. When such indicators were included in messages, the participants responded with significantly more polite messages (greeting and body than when the indicators were absent. The results boost our understanding of CMC with reference to politeness markers, and how they are used by Iranian EFL learners.

LHCb: F.E.C. for DAQ networks

CERN Multimedia

Floros, G; Neufeld, N

2014-01-01

The demand for faster and more reliable networks is growing day by day both in commercial and scientific applications, driving many innovations in network protocols, fiber optics and network-controllers. Operating fast links on relatively inexpensive hardware is a very important challenging aspect of this. One important way to enable this is to provide the network with an existing mechanism of error correction, called Forward Error Correction (F.E.C.). Although error-correcting codes exist for over six decades and F.E.C. is applied in various projects, it is still not widespread in Ethernet networks. F.E.C. introduces a very cost effective way to expand the limits of any network based on micro-controllers synthesized on FPGAs, but it is provided only for specific applications, such as backplane systems. Most of the FPGA and/or IP core vendors either do not provide this feature on their Ethernet implementations or their F.E.C. implementations are based on Ethernet micro-controllers that have a different struct...

A User Authentication Based on Personal History- A User Authentication System Using E-mail History -

Directory of Open Access Journals (Sweden)

Masakatsu Nishigaki

2007-04-01

Full Text Available This paper proposes a user authentication using personal history of each user. Here, authentication is done by giving answers to questions about the history of user's daily life. Users do not have to memorize any password, since the passwords are what users already know by experience. In addition, everyday-life experience increases day by day, and thus the question could change on every authentication trial. In this paper, a user authentication system using user's e-mail history is shown as a prototype of our proposal, and some basic experiments to evaluate the availability of the system are carried out.

CONFERENCING VIA E-MAIL: AN ALTERNATIVE WAY TO RESPOND TO STUDENT WRITING (LA CONFERENCIA VÍA E-MAIL: UNA MANERA ALTERNATIVA PARA RESPONDER A LOS ESCRITOS DE LOS ESTUDIANTES

Directory of Open Access Journals (Sweden)

Zúñiga Vargas Juan Pablo

2010-04-01

Full Text Available Resumen:El presente artículo reporta las conclusiones obtenidas en un proyecto de investigación cuyo objetivo fue determinar la eficacia de responder a los escritos de los estudiantes por medio de la conferencia vía correo electrónico. Dicho proyecto de investigación se realizó con nueve profesores de la facultad de ingeniería y un estudiante avanzado de ingeniería de una universidad pública de Costa Rica durante el segundo semestre del año 2008. Para reunir información para tal proyecto se utilizaron dos cuestionarios, formularios para conferencia, reflexiones del instructor y reflexiones de los estudiantes. Un número reducido de los estudiantes completó los instrumentos y participó en la interacción por medio de conferencias que se esperaba de ellos. Aún así, los estudiantes encuestados y el instructor consideraron que el método de la conferencia fue eficaz. No obstante, es necesario realizar más investigación con el fin de obtener resultados concluyentes sobre la efectividad de la conferencia vía correo electrónico para responder a los escritos de los estudiantes. Se ofrecen sugerencias para investigaciones futuras.Abstract:This article reports the findings obtained in a research project that aimed at determining the efficiency of responding to student writing by means of conferencing via e-mail. Such research project was carried out with nine professors from the faculty of engineering and one advanced engineering student at a public university in Costa Rica during the second semester in the year 2008. To collect information for this project, two questionnaires, conferencing forms, instructors’ reflections, and student reflections were used. A reduced number of the students completed the instruments and took part in the conferencing exchanges expected of them, yet both the surveyed students and the instructor found conferencing efficient. Still, more research is needed in order obtain conclusive results about the

EdF competing in the European electricity market. Interview with Francois Ailleret, Electricite de France, Paris

International Nuclear Information System (INIS)

Anon.

1996-01-01

The French nuclear power program was pushed through in order to reduce the country's dependence on imported fossil sources of energy. Nuclear power and hydro power have achieved a level of self-sufficiency in the energy sector of more than 50%. It should be emphasized that the French nuclear power program was largely self-financed. Electricite de France (EdF) considers itself well prepared for the European market, provided the creation of the single market implies that electricity rates are taken as a yardstick of competitiveness. Negotiations about a European directive on deregulating the electricity market were for the government to hold. EdF pleaded in favor of preserving for each country a certain leeway for shaping its own policy. The road to deregulation was to be opened, but the specific situation of each country was to be taken electricity to be passed through imposes narrow constraints upon an expansion of exchanges of electricity, and public acceptance is not very likely to be achieved for the construction of new international high voltage transmission lines. (orig.) [de

Mail distribution

CERN Multimedia

2007-01-01

Please note that starting from 1 March 2007, the mail distribution and collection times will be modified for the following buildings: 6, 8, 9, 10, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 29, 69, 40, 70, 101, 102, 109, 118, 152, 153, 154, 155, 166, 167, 169, 171, 174, 261, 354, 358, 576, 579 and 580. Complementary Information on the new times will be posted on the entry doors and left in the mail boxes of each building. TS/FM Group

PreciseMail anti-spam gateway allows users more control over spam definitions; unwanted email is eliminated with no false positives

CERN Multimedia

ten Bruggencate, J

2003-01-01

"PreciseMail Anti-Spam Gateway uses a combination of proven heuristic (rules-based) and artificial intelligence technologies that eliminates unwanted spam e-mail at an Internet gateway without filtering critical e-mail messages. Its highly effective filtering engine identifies spam and allows multiple levels of tuning and customization to meet each user's personal e-mail spam filtering requirements" (1 page).

78 FR 63915 - New Mailing Standards for Domestic Mailing Services Products

Science.gov (United States)

2013-10-25

... action, regardless of the class of mail or the extra service being purchased. This has resulted in... accountable mail, including a Return Receipt (Form 3811) purchased with the applicable extra service. Although... require a Form 1508 submission with the claim. Also, gift cards, most of which are replaceable, are being...

76 FR 37655 - Combined Mailings of Standard Mail and Periodicals Flats

Science.gov (United States)

2011-06-28

... Periodicals flats to be made using a minimum of six (6) pieces, as is currently permitted for Periodicals... Regulations to reflect that the Standard Mail service standards apply to all Periodicals flats pieces entered... for Standard Mail of 200 pieces or 50 pounds. Periodicals publications must be authorized or have a...

Analysis of E2F factors during epidermal differentiation.

Science.gov (United States)

Chang, Wing Y; Dagnino, Lina

2005-01-01

The multigene E2F family of transcription factors is central in the control of cell cycle progression. The expression and activity of E2F proteins is tightly regulated transcriptionally and posttranslationally as a function of the proliferation and differentiation status of the cell. In this chapter, we review protocols designed to determine E2F mRNA abundance in tissues by in situ hybridization techniques. The ability to culture primary epidermal keratinocytes and maintain them as either undifferentiated or terminally differentiated cells allows the biochemical and molecular characterization of changes in E2F expression and activity. Thus, we also discuss in detail methods to analyze E2F protein abundance by immunoblot and their ability to bind DNA in cultured cells using electrophoretic mobility shift assays.

Multiple metamorphoses for EdF and GdF

International Nuclear Information System (INIS)

Jemain, A.

2004-01-01

The draft of law, modifying the statute of the French electric and gas utilities, Electricite de France (EdF) and Gaz de France (GdF), that the French government has presented to the Council of State, mixes some European and French preoccupations. The reason is the urgency of the planning and the date line of July 1, 2004 with the opening of the gas and power markets to 3.5 millions of professionals. The draft includes the obligations and missions of public utility of both companies, the transposition of the European directives, the conclusions of the negotiation of retirement pensions with the syndicate organizations, and the transformation of both public companies into anonymous companies. Short paper. (J.S.)

Regulation of cell proliferation by the E2F transcription factors

DEFF Research Database (Denmark)

Helin, K

1998-01-01

Experimental data generated in the past year have further emphasized the essential role for the E2F transcription factors in the regulation of cell proliferation. Genetic studies have shown that E2F activity is required for normal development in fruitflies, and the generation of E2F-1(-/-) mice h......Fs in the proteasomes. Novel target genes for the E2F transcription factors have been identified that link the E2Fs directly to the initiation of DNA replication.......Experimental data generated in the past year have further emphasized the essential role for the E2F transcription factors in the regulation of cell proliferation. Genetic studies have shown that E2F activity is required for normal development in fruitflies, and the generation of E2F-1(-/-) mice has...... demonstrated that individual members of the E2F transcription factor family are likely to have distinct roles in mammalian development and homeostasis. Additional mechanisms regulating the activity of the E2F transcription factors have been reported, including subcellular localization and proteolysis of the E2...

PENGARUH PENERAPAN PERIKLANAN DI INTERNET DAN PEMASARAN MELALUI E-MAIL PRODUK UMKM DI WILAYAH DEPOK

Directory of Open Access Journals (Sweden)

Mujiyana Mujiyana

2013-03-01

Full Text Available Dewasa ini peran internet bukan hanya sebagai sarana mencari informasi, tapi juga mempunyai potensi besar sebagai media pemasaran dan perdagangan, khususnya periklanan. Bagi usaha mikro kecil dan menengah (UMKM, media periklanan melalui internet di Indonesia belum dimanfaatkan secara maksimal bahkan masih relatif kecil dan cenderung jauh dari sentuhan teknologi informasi yang mendukung kegiatan dan operasional perusahaan. Metode penelitian yang digunakan adalah deskriptif dan verifikatif. Konsep model penelitian ini adalah menguji kebenaran daru suatu hipotesis. Dalam penelitian ini telah dilakukan tiga tahapan selama tiga tahun berturut-turut, tahun pertama menguji manfaat penggunaan internet untuk periklanan bagi UMKM, tahun kedua membangun dan  mengembangkan portal situs web untuk periklanan produk UMKM, dan tahun ketiga mengukur pengaruh periklanan melalui internet bagi UMKM. Hasil penetilian dan kajian ini adalah produk teknologi infomasi yang dapat dimanfaatkan dalam pengelolaan usaha kecil, baik dari sisi kepentingan pelaku usaha maupun pihak terkait dalam pemberdayaan usaha kecil, dalam bentuk portal E-marketing yang dikelola oleh instansi pemerintah dan pihak asosiasi usaha kecil di wilayah kota Depok. Portal yang telah dibangun dapat diakses melalui http://www.gunadarma.ukmdepok.com Kata kunci : periklanan, e-commerce dan e-marketing, pemasaran melalui e-mail   Abstract Today the role of the Internet not only as a means of finding information, but it also has great potential as a medium of marketing and trade, particularly advertising. For micro small and medium enterprises (MSMEs, media advertising over the internet in Indonesia is not fully utilized even still relatively small and likely to be far from the touch of the information technology that supports the activities and operations of the company. The research method used is descriptive and verification. The concept model of this study was to test the truth of a hypothesis

76 FR 16460 - Mail Classification Change for Priority Mail Flat Mail

Science.gov (United States)

2011-03-23

... online model and the retail model. The online model will allow customers to purchase packs from a Web... offer those packs in their stores directly to their customers. The Postal Service includes five... noticing a recently-filed Postal Service request to provide Forever postage on Priority Mail Flat Rate...

Search for high mass photon pairs in e +e - → f overlinefγγ ( f= e, μ, τ, v, q) at LEP

Science.gov (United States)

Buskulic, D.; de Bonis, I.; Decamp, D.; Ghez, P.; Goy, C.; Lees, J.-P.; Minard, M.-N.; Pietrzyk, B.; Alemany, R.; Ariztizabal, F.; Comas, P.; Crespo, J. M.; Delfino, M.; Fernandez, E.; Fernandez-Bosman, M.; Gaitan, V.; Garrido, Ll.; Mattison, T.; Pacheco, A.; Padilla, C.; Pascual, A.; Creanza, D.; de Palma, M.; Farilla, A.; Iaselli, G.; Maggi, G.; Natali, S.; Nuzzo, S.; Quattromini, M.; Ranieri, A.; Raso, G.; Romano, F.; Ruggieri, F.; Selvaggi, G.; Silvestris, L.; Tempesta, P.; Zito, G.; Chai, Y.; Hu, H.; Huang, D.; Huang, X.; Lin, J.; Wang, T.; Xie, Y.; Xu, D.; Xu, R.; Zhang, J.; Zhang, L.; Zhao, W.; Blucher, E.; Bonvicini, G.; Boudreau, J.; Casper, D.; Drevermann, H.; Forty, R. W.; Ganis, G.; Gay, C.; Hagelberg, R.; Harvey, J.; Haywood, S.; Hilgart, J.; Jacobsen, R.; Jost, B.; Knobloch, J.; Lehraus, I.; Lohse, T.; Maggi, M.; Markou, C.; Martinez, M.; Mato, P.; Meinhard, H.; Minten, A.; Miotto, A.; Miquel, R.; Moser, H.-G.; Palazzi, P.; Pater, J. R.; Perlas, J. A.; Pusztaszeri, J.-F.; Ranjard, F.; Redlinger, G.; Rolandi, L.; Rothberg, J.; Ruan, T.; Saich, M.; Schlatter, D.; Schmelling, M.; Sefkow, F.; Tejessy, W.; Veenhof, R.; Wachsmuth, H.; Wiedenmann, W.; Wildish, T.; Witzeling, W.; Wotschack, J.; Ajaltouni, Z.; Badaud, F.; Bardadin-Otwinowska, M.; El Fellous, R.; Falvard, A.; Gay, P.; Guicheney, C.; Henrard, P.; Jousset, J.; Michel, B.; Montret, J.-C.; Pallin, D.; Perret, P.; Podlyski, F.; Proriol, J.; Prulhière, F.; Saadi, F.; Fearnley, T.; Hansen, J. D.; Hansen, J. R.; Hansen, P. H.; Møllerud, R.; Nilsson, B. S.; Efthymiopoulos, I.; Kyriakis, A.; Simopoulou, E.; Vayaki, A.; Zachariadou, K.; Badier, J.; Blondel, A.; Bonneaud, G.; Brient, J. C.; Fouque, G.; Orteu, S.; Rougé, A.; Rumpf, M.; Tanaka, R.; Verderi, M.; Videau, H.; Candlin, D. J.; Parsons, M. I.; Veitch, E.; Focardi, E.; Moneta, L.; Parrini, G.; Corden, M.; Georgiopoulos, C.; Ikeda, M.; Lannutti, J.; Levinthal, D.; Sawyer, L.; Wasserbaech, S.; Antonelli, A.; Baldini, R.; Bencivenni, G.; Bologna, G.; Bossi, F.; Campana, P.; Capon, G.; Cerutti, F.; Chiarella, V.; D'Ettorre-Piazzoli, B.; Felici, G.; Laurelli, P.; Mannocchi, G.; Murtas, F.; Murtas, G. P.; Passalacqua, L.; Pepe-Altarelli, M.; Picchi, P.; Colrain, P.; Ten Have, I.; Lynch, J. G.; Maitland, W.; Morton, W. T.; Raine, C.; Reeves, P.; Scarr, J. M.; Smith, K.; Smith, M. G.; Thompson, A. S.; Turnbull, R. M.; Brandl, B.; Braun, O.; Geweniger, C.; Hanke, P.; Hepp, V.; Kluge, E. E.; Maumary, Y.; Putzer, A.; Rensch, B.; Stahl, A.; Tittel, K.; Wunsch, M.; Beuselinck, R.; Binnie, D. M.; Cameron, W.; Cattaneo, M.; Colling, D. J.; Dornan, P. J.; Greene, A. M.; Hassard, J. F.; Lieske, N. M.; Moutoussi, A.; Nash, J.; Patton, S.; Payne, D. G.; Phillips, M. J.; San Martin, G.; Sedgbeer, J. K.; Tomalin, I. R.; Wright, A. G.; Girtler, P.; Kneringer, E.; Kuhn, D.; Rudolph, G.; Bowdery, C. K.; Brodbeck, T. J.; Finch, A. J.; Foster, F.; Hughes, G.; Jackson, D.; Keemer, N. R.; Nuttall, M.; Patel, A.; Sloan, T.; Snow, S. W.; Whelan, E. P.; Kleinknecht, K.; Raab, J.; Renk, B.; Sander, H.-G.; Schmidt, H.; Steeg, F.; Walther, S. M.; Wanke, R.; Wolf, B.; Bencheikh, A. M.; Benchouk, C.; Bonissent, A.; Carr, J.; Coyle, P.; Drinkard, J.; Etienne, F.; Nicod, D.; Paplexiou, S.; Payre, P.; Roos, L.; Rousseau, D.; Schwemling, P.; Talby, M.; Adlung, S.; Assmann, R.; Bauer, C.; Blum, W.; Brown, D.; Cattaneo, P.; Dehning, B.; Dietl, H.; Dydak, F.; Frank, M.; Halley, A. W.; Jacobs, K.; Lauber, J.; Lütjens, G.; Lutz, G.; Männer, W.; Richter, R.; Schröder, J.; Schwarz, A. S.; Settles, R.; Seywerd, H.; Stierlin, U.; Stiegler, U.; St. Denis, R.; Wolf, G.; Boucrot, J.; Callot, O.; Cordier, A.; Davier, M.; Duflot, L.; Grivaz, J.-F.; Heusse, Ph.; Jaffe, D. E.; Janot, P.; Kim, D. W.; Le Diberder, F.; Lefrançois, J.; Lutz, A.-M.; Schune, M.-H.; Veillet, J.-J.; Videau, I.; Zhang, Z.; Abbaneo, D.; Bagliesi, G.; Batignani, G.; Bottigli, U.; Bozzi, C.; Calderini, G.; Carpinelli, M.; Ciocci, M. A.; Dell'Orso, R.; Ferrante, I.; Fidecaro, F.; Foà, L.; Forti, F.; Giassi, A.; Giorgi, M. A.; Gregorio, A.; Ligabue, F.; Lusiani, A.; Mannelli, E. B.; Marrocchesi, P. S.; Messineo, A.; Palla, F.; Rizzo, G.; Sanguinetti, G.; Spagnolo, P.; Steinberger, J.; Tenchini, R.; Tonelli, G.; Triggiani, G.; Vannini, C.; Venturi, A.; Verdini, P. G.; Walsh, J.; Betteridge, A. P.; Carter, J. M.; Gao, Y.; Green, M. G.; March, P. V.; Mir, Ll. M.; Medcalf, T.; Quazi, I. S.; Strong, J. A.; West, L. R.; Botterill, D. R.; Clifft, R. W.; Edgecock, T. R.; Edwards, M.; Fisher, S. M.; Jones, T. J.; Norton, P. R.; Salmon, D. P.; Thompson, J. C.; Bloch-Devaux, B.; Colas, P.; Duarte, H.; Emery, S.; Kozanecki, W.; Lançon, E.; Lemaire, M. C.; Locci, E.; Marx, B.; Perez, P.; Rander, J.; Renardy, J.-F.; Rosowsky, A.; Roussarie, A.; Schuller, J.-P.; Schwindling, J.; Si Mohand, D.; Vallage, B.; Johnson, R. P.; Litke, A. M.; Taylor, G.; Wear, J.; Ashman, J. G.; Babbage, W.; Booth, C. N.; Buttar, C.; Cartwright, S.; Combley, F.; Dawson, I.; Thompson, L. F.; Barberio, E.; Böhrer, A.; Brandt, S.; Cowan, G.; Grupen, C.; Lutters, G.; Rivera, F.; Schäfer, U.; Smolik, L.; Bosisio, L.; Della Marina, R.; Giannini, G.; Gobbo, B.; Ragusa, F.; Bellantoni, L.; Chen, W.; Cinabro, D.; Conway, J. S.; Cowen, D. F.; Ferguson, D. P. S.; Gao, Y. S.; Grahl, J.; Harton, J. L.; Jared, R. C.; Leclaire, B. W.; Lishka, C.; Pan, Y. B.; Saadi, Y.; Schmitt, M.; Sharma, V.; Shi, Z. H.; Walsh, A. M.; Weber, F. V.; Wu, Sau Lan; Wu, X.; Zheng, M.; Zobernig, G.; Aleph Collaboration

1993-07-01

The result of a search for high mass photon pairs from the processes e +e - → f overlinefγγ (f = e, μ, τ, v and q) with the ALEPH detector is reported. The result for f = e, μ and τ is to be compared with the observation of 4 events by the L3 Collaboration with invariant masses, Mγγ, of the two photons near 60 GeV. From a data sample approximately twice as large taken from 1990 to 1992, 6 events are found with Mγγ distributed between 50 GeV and 72 GeV, while 4.9 events are expected from a QED calculation. There is no evidence for a mass peak; only one event ( μ+μ-γγ) at Mγγ = 59.4 ± 0.2 GeV is compatible with the L3 observation. In addition, for Mγγ > 50 GeV, no event is found for e +e - → q overlineqγγ and only one event is found consistent with e +e - → v overlinevγγ ; this event has Mγγ = 58.5 ± 1.9 GeV. High mass photon pair events have also been searched for in γγ collisions. This allows one to set an upper limit of 50 MeV for the width of an assumed resonance decaying to photon pairs.

Proceedings of the second workshop of LHC Computing Grid, LCG-France; ACTES, 2e colloque LCG-France

Energy Technology Data Exchange (ETDEWEB)

Chollet, Frederique; Hernandez, Fabio; Malek, Fairouz; Gaelle, Shifrin (eds.) [Laboratoire de Physique Corpusculaire Clermont-Ferrand, Campus des Cezeaux, 24, avenue des Landais, Clermont-Ferrand (France)

2007-03-15

The second LCG-France Workshop was held in Clermont-Ferrand on 14-15 March 2007. These sessions organized by IN2P3 and DAPNIA were attended by around 70 participants working with the Computing Grid of LHC in France. The workshop was a opportunity of exchanges of information between the French and foreign site representatives on one side and delegates of experiments on the other side. The event allowed enlightening the place of LHC Computing Task within the frame of W-LCG world project, the undergoing actions and the prospects in 2007 and beyond. The following communications were presented: 1. The current status of the LHC computation in France; 2.The LHC Grid infrastructure in France and associated resources; 3.Commissioning of Tier 1; 4.The sites of Tier-2s and Tier-3s; 5.Computing in ALICE experiment; 6.Computing in ATLAS experiment; 7.Computing in the CMS experiments; 8.Computing in the LHCb experiments; 9.Management and operation of computing grids; 10.'The VOs talk to sites'; 11.Peculiarities of ATLAS; 12.Peculiarities of CMS and ALICE; 13.Peculiarities of LHCb; 14.'The sites talk to VOs'; 15. Worldwide operation of Grid; 16.Following-up the Grid jobs; 17.Surveillance and managing the failures; 18. Job scheduling and tuning; 19.Managing the site infrastructure; 20.LCG-France communications; 21.Managing the Grid data; 22.Pointing the net infrastructure and site storage. 23.ALICE bulk transfers; 24.ATLAS bulk transfers; 25.CMS bulk transfers; 26. LHCb bulk transfers; 27.Access to LHCb data; 28.Access to CMS data; 29.Access to ATLAS data; 30.Access to ALICE data; 31.Data analysis centers; 32.D0 Analysis Farm; 33.Some CMS grid analyses; 34.PROOF; 35.Distributed analysis using GANGA; 36.T2 set-up for end-users. In their concluding remarks Fairouz Malek and Dominique Pallin stressed that the current workshop was more close to users while the tasks for tightening the links between the sites and the experiments were definitely achieved. The IN2P3

Social Studies by Electronic Mail.

Science.gov (United States)

Barr, Hugh

1994-01-01

Asserts that electronic mail provides opportunities to engage students actively in cross-cultural contact with students in other nations. Discusses advantages and problems with using electronic mail in the social studies classroom. Describes electronic mail projects that link students in New Zealand, England, and the United States. (CFR)

Proposal for the award of an industrial service contract for stores operations and relatedlogistics, in-house mail distribution and transport services on the CERN site

CERN Document Server

2006-01-01

This document concerns the award of an industrial support contract for stores operations and related logistics, in-house mail distribution and transport services on the CERN site. The Finance Committee is invited to agree to the negotiation of a contract with the consortium ISS (CH) - ISS (ES), for stores operations and related logistics, in-house mail distribution and transport services on the CERN site for a period of three years for a total amount not exceeding 10 312 028 Swiss francs not subject to revision. The contract will include options for two one-year extensions beyond the initial three-year period.

76 FR 76619 - International Mail: New Prices and Fee Changes-Mailing Services

Science.gov (United States)

2011-12-08

... fraction thereof)......... 0.80 Duplicate copy of PS Form 3606 1.15 * * * * * International Business Reply Service (382) [For each country that offers International Business Reply Service, revise the fees to read... POSTAL SERVICE 39 CFR Part 20 International Mail: New Prices and Fee Changes--Mailing Services...

39 CFR 121.3 - Standard Mail.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Standard Mail. 121.3 Section 121.3 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] SERVICE STANDARDS FOR MARKET-DOMINANT MAIL PRODUCTS § 121.3 Standard Mail. (a) End-to-End. (1) The service standard for Sectional Center...

Directly e-mailing authors of newly published papers encourages community curation

Science.gov (United States)

Bunt, Stephanie M.; Grumbling, Gary B.; Field, Helen I.; Marygold, Steven J.; Brown, Nicholas H.; Millburn, Gillian H.

2012-01-01

Much of the data within Model Organism Databases (MODs) comes from manual curation of the primary research literature. Given limited funding and an increasing density of published material, a significant challenge facing all MODs is how to efficiently and effectively prioritize the most relevant research papers for detailed curation. Here, we report recent improvements to the triaging process used by FlyBase. We describe an automated method to directly e-mail corresponding authors of new papers, requesting that they list the genes studied and indicate (‘flag’) the types of data described in the paper using an online tool. Based on the author-assigned flags, papers are then prioritized for detailed curation and channelled to appropriate curator teams for full data extraction. The overall response rate has been 44% and the flagging of data types by authors is sufficiently accurate for effective prioritization of papers. In summary, we have established a sustainable community curation program, with the result that FlyBase curators now spend less time triaging and can devote more effort to the specialized task of detailed data extraction. Database URL: http://flybase.org/ PMID:22554788

Aims and first assessments of the French hydrogen pathways project HyFrance3

Energy Technology Data Exchange (ETDEWEB)

Le Duigou, Alain [CEA/DEN/DANS/I-Tese, Gif-sur-Yvette (France); Quemere, Marie-Marguerite [EDF R et D, Moret sur Loing (France). Dept. EPI; Marion, Pierre [IFP, Rueil Malmaison (FR)] (and others)

2010-07-01

The HyFrance Group was originally formed in France to support the European project HyWays, by providing (former projects HyFrance1 and HyFrance2) the French data and possible hydrogen pathways according to national specificities. HyFrance3 is a new project that focuses on the economic competitiveness of different steps of the hydrogen chain, from the production to end usage, at the time horizon of 2030 in France. The project is coordinated by CEA with the other partners being: ADEME (co-funding), AFH2, CNRS, IFP, Air Liquide, EdF, GdF Suez, TOTAL, ALPHEA. The project is divided into 4 sub-projects, that address present and future French hydrogen industrial markets for chemical and refinery uses, the analysis of the interplay between wind energy production and storage of hydrogen for different automotive requirements (refuelling stations, BtL plants, H2/NG mix), massive hydrogen storage to balance various offer and demand characteristics, and the supply network (pipeline option competitiveness vs. trucked in supply) to distribute hydrogen in a French region for automotive applications. Technical and economical issues, as well as GHG emissions, are addressed. (orig.)

FLUXUS E ARTE POSTAL COMO ARTE RELACIONAL: BREVE ESTUDO

OpenAIRE

Amizo, Isadora Banducci

2014-01-01

Este artigo tem como objetivo a análise das questões que envolvem a produção da Arte postal ou Mail art, e do grupo Fluxus, difundidas ao redor do mundo a partir da década de 1960. Procura-se investigar sua aproximação com o conceito de arte relacional, exposto pelo crítico e filósofo francês Nicolas Bourriaud no livro “Estética relacional”. Para isso, são revisadas algumas das temáticas que envolvem as duas expressões artísticas destacando–se a produção de alguns de seus principais expoentes...

Enterovirus Migration Patterns between France and Tunisia.

Science.gov (United States)

Othman, Ines; Mirand, Audrey; Slama, Ichrak; Mastouri, Maha; Peigue-Lafeuille, Hélène; Aouni, Mahjoub; Bailly, Jean-Luc

2015-01-01

The enterovirus (EV) types echovirus (E-) 5, E-9, and E-18, and coxsackievirus (CV-) A9 are infrequently reported in human diseases and their epidemiologic features are poorly defined. Virus transmission patterns between countries have been estimated with phylogenetic data derived from the 1D/VP1 and 3CD gene sequences of a sample of 74 strains obtained in France (2000-2012) and Tunisia (2011-2013) and from the publicly available sequences. The EV types (E-5, E-9, and E-18) exhibited a lower worldwide genetic diversity (respective number of genogroups: 4, 5, and 3) in comparison to CV-A9 (n = 10). The phylogenetic trees estimated with both 1D/VP1 and 3CD sequence data showed variations in the number of co-circulating lineages over the last 20 years among the four EV types. Despite the low number of genogroups in E-18, the virus exhibited the highest number of recombinant 3CD lineages (n = 10) versus 4 (E-5) to 8 (E-9). The phylogenies provided evidence of multiple transportation events between France and Tunisia involving E-5, E-9, E-18, and CV-A9 strains. Virus spread events between France and 17 other countries in five continents had high probabilities of occurrence as those between Tunisia and two European countries other than France. All transportation events were supported by BF values > 10. Inferring the source of virus transmission from phylogenetic data may provide insights into the patterns of sporadic and epidemic diseases caused by EVs.

E2F8 is essential for polyploidization in mammalian cells.

Science.gov (United States)

Pandit, Shusil K; Westendorp, Bart; Nantasanti, Sathidpak; van Liere, Elsbeth; Tooten, Peter C J; Cornelissen, Peter W A; Toussaint, Mathilda J M; Lamers, Wouter H; de Bruin, Alain

2012-11-01

Polyploidization is observed in all mammalian species and is a characteristic feature of hepatocytes, but its molecular mechanism and biological significance are unknown. Hepatocyte polyploidization in rodents occurs through incomplete cytokinesis, starts after weaning and increases with age. Here, we show in mice that atypical E2F8 is induced after weaning and required for hepatocyte binucleation and polyploidization. A deficiency in E2f8 led to an increase in the expression level of E2F target genes promoting cytokinesis and thereby preventing polyploidization. In contrast, loss of E2f1 enhanced polyploidization and suppressed the polyploidization defect of hepatocytes deficient for atypical E2Fs. In addition, E2F8 and E2F1 were found on the same subset of target promoters. Contrary to the long-standing hypothesis that polyploidization indicates terminal differentiation and senescence, we show that prevention of polyploidization through inactivation of atypical E2Fs has, surprisingly, no impact on liver differentiation, zonation, metabolism and regeneration. Together, these results identify E2F8 as a repressor and E2F1 as an activator of a transcriptional network controlling polyploidization in mammalian cells.

Internet versus mail

DEFF Research Database (Denmark)

Olsen, Søren Bøye

In a choice experiment setup, this paper suggests that internet surveys can be a viable alternative to traditional mail surveys when gathering feedback from a sample of respondents. In a study concerning preferences for avoiding encroachment of nature areas in future motorway planning in Denmark......, two samples of respondents are surveyed – one by internet and one by mail. Results suggest that additional self-selection mechanisms in the internet survey mode lead to the internet sample being less representative of the survey population than is the case for the mail sample. Similar response rates...... are obtained in the two samples, but the internet sample is apparently less prone to protest bidding. A thorough parametric analysis cannot reject that stated preferences elicited by use of the two different modes of sampling are identical. This suggests that the fear of a potential survey mode effect...

Coding for Electronic Mail

Science.gov (United States)

Rice, R. F.; Lee, J. J.

1986-01-01

Scheme for coding facsimile messages promises to reduce data transmission requirements to one-tenth current level. Coding scheme paves way for true electronic mail in which handwritten, typed, or printed messages or diagrams sent virtually instantaneously - between buildings or between continents. Scheme, called Universal System for Efficient Electronic Mail (USEEM), uses unsupervised character recognition and adaptive noiseless coding of text. Image quality of resulting delivered messages improved over messages transmitted by conventional coding. Coding scheme compatible with direct-entry electronic mail as well as facsimile reproduction. Text transmitted in this scheme automatically translated to word-processor form.

Christine Bard, Sylvie Chaperon (dirs), Dictionnaire des féministes. France xviiie-

OpenAIRE

Rouch, Marine

2017-01-01

Dix années auront été nécessaires pour la réalisation de cet ouvrage, véritable événement éditorial de l’année 2017 pour celles et ceux qui s’intéressent de près ou de loin au féminisme, à ses figures, à ses groupes. Comme l’indiquent Christine Bard et Sylvie Chaperon, les directrices de publication, il est désormais le premier du genre à alimenter l’« espace mémoriel immatériel du féminisme » (p. IX) et à inviter au « voyage dans le temps et l’espace du féminisme » (p. X). Il faut souligner ...

Lif Spectroscopy of ThF and the Preparation of ThF^{+} for the Jila eEDM Experiment

Science.gov (United States)

Ng, Kia Boon; Zhou, Yan; Gresh, Dan; Cairncross, William; Roussy, Tanya; Shagam, Yuval; Cheng, Lan; Ye, Jun; Cornell, Eric

2017-06-01

ThF^{+} is a promising candidate for a second-generation molecular ion-based measurement of the permanent electric dipole moment of the electron (eEDM). Compared to the current HfF^{+} eEDM experiment, ThF^{+} has several advantages: (i) the eEDM-sensitive ^{3}Δ_1 electronic state is the ground state, which facilitates a long measurement coherence time; (ii) its effective electric field (38 GV/cm) is 50% larger than that of HfF+, which promises a direct increase of the eEDM sensitivity; and (iii) the ionization energy of neutral ThF is lower than its dissociation energy, which introduces a greater flexibility for rotational state-selective photoionization via core-nonpenetrating Rydberg states. We use laser-induced fluorescence (LIF) spectroscopy to find suitable intermediate states required for the state selective ionization process. We present the results of our LIF spectroscopy of ThF, and our current progress on efficient ThF ionization and on ThF^{+} dissociation.

Training at Electricite de France

International Nuclear Information System (INIS)

Rippon, S.

1985-01-01

With 41 nuclear power units operating and another 21 units under construction, France is serious about improving personnel training for the 3000 new employees each year. Electricite de France (EdF) takes a paternalistic approach to personnel training and to recruitment and advancement from within the organization. Courses in the training program range from one day to one year in length, and may take place either on or off the site. The author describes the training centers and schedule, but emphasizes the training is an ongoing process. Most instructors come from operating power stations. The courses use simulators to train operators in the use of fault analysis during an emergency. Computer-aided teaching systems are also widely used. 1 figure

FOREIGN DRIVING LICENCES IN FRANCE

CERN Multimedia

Service des relations avec les Pays Hôtes

2000-01-01

1. PERSONS RESIDING IN FRANCE1.1 National driving licences from countries belonging to the EEAa) ValidityCurrent national driving licences issued by a country belonging to the European Economic Area (here inafter called EEA) are, in principle, valid in France. N.B. : The countries belonging to the EEA are Austria, Belgium, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Italy, Liechtenstein, Luxembourg, Netherlands, Norway, Portugal, Spain, Sweden and the United Kingdom.b)\tRegistrationTo ensure that all the conditions of validity in France have been met, holders of driving licences issued by a country belonging to the EEA, who reside in France (i.e. hold a residence permit issued by a Préfecture, or a carte spéciale issued by the French Ministry of Foreign Affairs, which is equivalent to a residence permit), can have their licences registered with the Préfecture of the department where they live (for Ain, call 04 74 32 30 00, for Haute Savoie call 04 50 33 ...

The retinoblastoma protein binds to a family of E2F transcription factors

DEFF Research Database (Denmark)

Lees, J A; Saito, M; Vidal, M

1993-01-01

E2F is a transcription factor that helps regulate the expression of a number of genes that are important in cell proliferation. Recently, several laboratories have isolated a cDNA clone that encodes an E2F-like protein, known as E2F-1. Subsequent characterization of this protein showed that it had...... the properties of E2F, but it was difficult to account for all of the suggested E2F activities through the function of this one protein. Using low-stringency hybridization, we have isolated cDNA clones that encode two additional E2F-like proteins, called E2F-2 and E2F-3. The chromosomal locations of the genes...... protein in vivo. Finally, E2F-2 and E2F-3 were able to activate transcription of E2F-responsive genes in a manner that was dependent upon the presence of at least one functional E2F binding site. These observations suggest that the E2F activities described previously result from the combined action...

The Impact of Gender on the Quality and Content of E-Mail Advice Professors Give to Students Applying to Graduate School

Science.gov (United States)

Steinpreis, Rhea E.; Anders, Katie A.; Riley, Monica G.; Ritzke, Dawn M.; McDonald, Theodore W.

The purpose of this study was to determine if gender plays a role in the quality and quantity of the advice given to undergraduates about applying to graduate school. Four hundred male and female psychologists who listed a university address and e-mail address in the 1997 Directory of the American Psychological Association were sent an e-mail inquiry from a pseudostudent (either Theresa or Brian Miller). In the first e-mail, the pseudostudent asked if the subjects would be willing to look at his or her GRE scores and grade point average (GPA) for the purpose of providing advice about his or her chances of getting into the graduate program at the subject's school. Two hundred forty subjects consented to examine the figures, nearly equally split between males and females. Subjects were then sent the GPA and scores of an outstanding, average, or poor applicant. The results indicated that female faculty were significantly more likely to consent to examine the data of a female pseudostudent and male faculty were significantly more likely to consent to examine the data of a male pseudostudent. However, once the faculty member agreed to offer advice, gender had no impact on the length or quality of advice given to the pseudostudent, and advice became a function of the pseudostudent's academic credentials. Furthermore, while male and female subjects were equally likely to encourage, discourage, or recant on their offer to give feedback, male subjects were more likely to refuse to review the data and female subjects were more likely to offer a neutral response to the data. The results are discussed in terms of the difficulty students face in finding adequate information about pursuing a graduate education. These problems may be magnified for female students because there are fewer female faculty available to serve as mentors.

1994 - a vintage year for safety in France

International Nuclear Information System (INIS)

Frantzen, C.

1995-01-01

With 54 operating PWR units (plus one fast reactor) in its ''nuclear fleet'', EdF (Electricite de France) has now logged more than 584 reactor years of operation. The value of this experience was demonstrated again in 1994 when no incident at or above level 3 on the International Nuclear Event Scale (INES) occurred. EdF has been free of level 3 incidents since 1989. (author)

How new subscribers use cancer-related online mailing lists.

Science.gov (United States)

Rimer, Barbara K; Lyons, Elizabeth J; Ribisl, Kurt M; Bowling, J Michael; Golin, Carol E; Forlenza, Michael J; Meier, Andrea

2005-07-01

Online cancer-related support is an under-studied resource that may serve an important function in the information seeking, care, and support of cancer patients and their families. With over 9.8 million cancer survivors (defined as anyone living with cancer) in the United States alone and the number growing worldwide, it is important to understand how they seek and use online resources to obtain the information they need, when they need it, and in a form and manner appropriate to them. These are stated cancer communication goals of the US National Cancer Institute. Our purposes are to (1) present background information about online mailing lists and electronic support groups, (2) describe the rationale and methodology for the Health eCommunities (HeC) study, and (3) present preliminary baseline data on new subscribers to cancer-related mailing lists. In particular, we describe subscribers' use of mailing lists, their reasons for using them, and their reactions to participating shortly after joining the lists. From April to August 2004, we invited all new subscribers to 10 Association of Cancer Online Resources mailing lists to complete Web-based surveys. We analyzed baseline data from the respondents to examine their perceptions about cancer-related mailing lists and to describe how cancer patients and survivors used these lists in the period shortly after joining them. Cumulative email invitations were sent to 1368 new mailing list subscribers; 293 Web surveys were completed within the allotted time frame (21.4% response rate). Most respondents were over age 50 (n = 203, 72%), white (n = 286, 98%), college graduates (n = 161, 55%), and had health insurance (n = 283, 97%). About 41% (n = 116) of new subscribers reported spending 1 to 3 hours per day reading and responding to list messages. They used the mailing lists for several reasons. Among the most frequently reported, 62% (n = 179) strongly agreed they used mailing lists to obtain information on how to deal

Echinococcus ortleppi Infections in Humans and Cattle, France

Science.gov (United States)

Umhang, Gérald; Arbez-Gindre, Francine; Mantion, Georges; Delabrousse, Eric; Millon, Laurence; Boué, Franck

2014-01-01

In 2011 and 2012, liver infections caused by Echinococcus ortleppi tapeworms were diagnosed in 2 humans in France. In 2012, a nationwide slaughterhouse survey identified 7 E. ortleppi infections in cattle. The foci for these infections were spatially distinct. The prevalence of E. ortleppi infections in France may be underestimated. PMID:25417697

The international development of Electricite de France; Le developpement international d'Electricite de France

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

In 2001, Electricite de France (EdF) has pursued and increased its international development with a portfolio of participations in foreign electricity companies (Germany, Italy, UK, Brazil, Argentina etc..) that reached 6 billions of euros. This development has been tainted with poor results in South America and has led to some hostile reactions from the Italian and Spanish governments. (J.S.)

E2F1 regulates cellular growth by mTORC1 signaling.

Directory of Open Access Journals (Sweden)

Sebastian Real

2011-01-01

Full Text Available During cell proliferation, growth must occur to maintain homeostatic cell size. Here we show that E2F1 is capable of inducing growth by regulating mTORC1 activity. The activation of cell growth and mTORC1 by E2F1 is dependent on both E2F1's ability to bind DNA and to regulate gene transcription, demonstrating that a gene induction expression program is required in this process. Unlike E2F1, E2F3 is unable to activate mTORC1, suggesting that growth activity could be restricted to individual E2F members. The effect of E2F1 on the activation of mTORC1 does not depend on Akt. Furthermore, over-expression of TSC2 does not interfere with the effect of E2F1, indicating that the E2F1-induced signal pathway can compensate for the inhibitory effect of TSC2 on Rheb. Immunolocalization studies demonstrate that E2F1 induces the translocation of mTORC1 to the late endosome vesicles, in a mechanism dependent of leucine. E2F1 and leucine, or insulin, together affect the activation of S6K stronger than alone suggesting that they are complementary in activating the signal pathway. From these studies, E2F1 emerges as a key protein that integrates cell division and growth, both of which are essential for cell proliferation.

Electronic Mail and the Writing Instructor.

Science.gov (United States)

Hawisher, Gail E.; Moran, Charles

1993-01-01

Discusses the growing importance of electronic mail among academicians. Offers a rhetoric and a pedagogy that include electronic mail in their fields of vision. Argues that writing instructors should continue to do research into the issues inherent in electronic mail. (HB)

Contrast enhancement of mail piece images

Science.gov (United States)

Shin, Yong-Chul; Sridhar, Ramalingam; Demjanenko, Victor; Palumbo, Paul W.; Hull, Jonathan J.

1992-08-01

A New approach to contrast enhancement of mail piece images is presented. The contrast enhancement is used as a preprocessing step in the real-time address block location (RT-ABL) system. The RT-ABL system processes a stream of mail piece images and locates destination address blocks. Most of the mail pieces (classified into letters) show high contrast between background and foreground. As an extreme case, however, the seasonal greeting cards usually use colored envelopes which results in reduced contrast osured by an error rate by using a linear distributed associative memory (DAM). The DAM is trained to recognize the spectra of three classes of images: with high, medium, and low OCR error rates. The DAM is not forced to make a classification every time. It is allowed to reject as unknown a spectrum presented that does not closely resemble any that has been stored in the DAM. The DAM was fairly accurate with noisy images but conservative (i.e., rejected several text images as unknowns) when there was little ground and foreground degradations without affecting the nondegraded images. This approach provides local enhancement which adapts to local features. In order to simplify the computation of A and (sigma) , dynamic programming technique is used. Implementation details, performance, and the results on test images are presented in this paper.

Cosmologia e física

Directory of Open Access Journals (Sweden)

Halton Arp

2000-05-01

Full Text Available Observações de objetos extragaláticos mostram que seus desvios para o vermelho são uma função de suas idades ao invés de suas velocidades de recessão. Para tanto não é necessária uma solução do tipo "Big Bang" para compreender o comportamento do Universo. Tratamentos distintos da teoria da relatividade (TR, as novas soluções requerem um espaço plano (Euclideano, um sistema de referência primário e, ambos, um tempo universal como também tempos de objetos individuais. Recentes análises da física local indicam que estas mesmas propriedades podem ser usadas para satisfazer experiências clássicas de TR.. É discutido que um raciocínio simples e não matemático requer estas propriedades para as novas soluções e regras fora das suposições habituais da TR. A extensa dominação, através do século, de uma física fundamentalmente inadequada parece que se deveu a uma avaliação não crítica da relação entre a Academia e a mídia.

75 FR 10529 - Mail Classification Change

Science.gov (United States)

2010-03-08

... POSTAL REGULATORY COMMISSION [Docket Nos. MC2010-19; Order No. 415] Mail Classification Change...-filed Postal Service request to make a minor modification to the Mail Classification Schedule. The.... concerning a change in classification which reflects a change in terminology from Bulk Mailing Center (BMC...

CFD Analysis of a Maneuvering F/A-18E Super Hornet

Science.gov (United States)

2016-10-12

tools for aircraft, ships, and radio - frequency antenna design and analysis. The resulting program is called the Computational Research and Engineering...accurately predicting the forces and moments on the F/A-18E Super Hornet while performing several complicated maneuvers. Past F/A-18E computational studies... predicting the forces and moments on the F/A-18E Super Hornet while performing several complicated maneuvers. Past F/A-18E computational studies have

2003 annual results of EdF group

International Nuclear Information System (INIS)

2004-03-01

The Electricite de France (EdF) group Board of Directors, meeting on March 11, 2004, under the Chairmanship of Francois Roussely, reviewed the audited consolidated financial statements for the year ended 12/31/2003. This document presents the consolidated results of EdF group for 2003: consolidated financial statements, highlights of the year, focus on 2003 events, commercial results, EDF in Europe and worldwide, EDF France highlights, key figures. (J.S.)

Le probleme du controle de la liquidité en France. (The problem of controlling liquidity in France

Directory of Open Access Journals (Sweden)

H. FOURNIER

2014-07-01

Full Text Available The idea of liquidity in France finds expression in more or less the same way as in the other western countries. It is normal practice to distinguish between the “liquidity of the economy” on the one hand, and the “liquidity of the banking system” on the other. The former corresponds to the money supply, while the latter comprises the banks’ holdings of notes and coin and their balances on sight accounts with the Bank of France, together with the total amount of the items which they can put into the Bank of France. The methods of influencing liquidity are also similar to those employed in other countries. However, to make them easier to understand, the present article first recalls certain special features of France’s monetary institutions, namely the banks, the specialised institutions and the Treasury. The author then examines the duel problems of controlling the liquidity of the economy and bank liquidity.JEL: E51, E52, E58, G21

Migração e telecomunicações: tecnologias e famílias transnacionais na França e África Ocidental Migration and telecommunications: technologies and transnational families in France and West Africa

Directory of Open Access Journals (Sweden)

Carolyn Sargent

2007-12-01

Full Text Available Através da comparação de conexões e interações entre França e África Ocidental e do uso das telecomunicações por imigrantes chegando à França em períodos diversos entre 1965 e 2005, este artigo demonstra a relevância dessas tecnologias de comunicação na (redefinição da distância social e na facilitação do envolvimento continuado de migrantes na tomada de decisões familiares nas suas comunidades de origem.Through the comparison of social connections and interactions between France and West Africa and the use of telecommunications by migrants arriving in France at differing periods between 1965 and 2005, this article demonstrates the significance of these communication technologies in (redefining social distance and facilitating the continued involvement of migrants in family decision making in the original communities.

Electronic Mail for Personal Computers: Development Issues.

Science.gov (United States)

Tomer, Christinger

1994-01-01

Examines competing, commercially developed electronic mail programs and how these technologies will affect the functionality and quality of electronic mail. How new standards for client-server mail systems are likely to enhance messaging capabilities and the use of electronic mail for information retrieval are considered. (Contains eight…

Evaluation of E.M.F. exposure from medical electrical equipment

Energy Technology Data Exchange (ETDEWEB)

Aniolczyk, H.; Mamrot, P.; Politanski, P. [Nofer Institute of Occupational Medicine, Lodz (Poland)

2006-07-01

he medical electric and electronic equipment, including electro surgical devices, short- and microwave diathermy units, and magnetic resonance imaging (MRI) systems, belong to the most hazardous sources of electromagnetic emissions. The electromagnetic emissions can interfere with emissions from other medical equipment located in the same facility (e.g. operation rooms) thus having impact on their work, but more importantly, they can be dangerous to patients, medical personnel operating them and other persons. In the present project, an assessment of E.M.F. intensity was performed for more than 2 000 electro surgical devices (330 khz, 440 khz and 1.76 MHz frequency ranges), 1 200 diathermy units and 45 MRI 0.2 - 1.5 T systems. E.M.F. exposure of medical staff was assessed based on respective national hygienic standards. The actual exposure levels were found to exceed the admissible values in Poland. The recorded E.M.F. intensities were compared with relevant Who and U E recommendations (e.g. I.C.N.I.R.P. guidelines, 1998, Directive 2004/40/E.C.). The findings revealed that for 18% of the devices examined, the E.M.F. was higher than the E.M.F. intensity values recommended by U E. (authors)

Evaluation of E.M.F. exposure from medical electrical equipment

International Nuclear Information System (INIS)

Aniolczyk, H.; Mamrot, P.; Politanski, P.

2006-01-01

he medical electric and electronic equipment, including electro surgical devices, short- and microwave diathermy units, and magnetic resonance imaging (MRI) systems, belong to the most hazardous sources of electromagnetic emissions. The electromagnetic emissions can interfere with emissions from other medical equipment located in the same facility (e.g. operation rooms) thus having impact on their work, but more importantly, they can be dangerous to patients, medical personnel operating them and other persons. In the present project, an assessment of E.M.F. intensity was performed for more than 2 000 electro surgical devices (330 khz, 440 khz and 1.76 MHz frequency ranges), 1 200 diathermy units and 45 MRI 0.2 - 1.5 T systems. E.M.F. exposure of medical staff was assessed based on respective national hygienic standards. The actual exposure levels were found to exceed the admissible values in Poland. The recorded E.M.F. intensities were compared with relevant Who and U E recommendations (e.g. I.C.N.I.R.P. guidelines, 1998, Directive 2004/40/E.C.). The findings revealed that for 18% of the devices examined, the E.M.F. was higher than the E.M.F. intensity values recommended by U E. (authors)

21 CFR 1321.01 - DEA mailing addresses.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 9 2010-04-01 2010-04-01 false DEA mailing addresses. 1321.01 Section 1321.01 Food and Drugs DRUG ENFORCEMENT ADMINISTRATION, DEPARTMENT OF JUSTICE DEA MAILING ADDRESSES § 1321.01 DEA mailing addresses. The following table provides information regarding mailing addresses to be used...

34 CFR 300.505 - Electronic mail.

Science.gov (United States)

2010-07-01

... 34 Education 2 2010-07-01 2010-07-01 false Electronic mail. 300.505 Section 300.505 Education... DISABILITIES Procedural Safeguards Due Process Procedures for Parents and Children § 300.505 Electronic mail. A....508 by an electronic mail communication, if the public agency makes that option available. (Authority...

Perfil da aspartato aminotransferase e alanina aminotransferase e biometria do fígado de codornas japonesas

OpenAIRE

Barbosa,Anderson de Almeida; Müller,Elisa Sialino; Moraes,George Henrique Kling de; Umigi,Regina Tie; Barreto,Sergio Luiz de Toledo; Ferreira,Ronaldo Martins

2010-01-01

Objetivou-se determinar o perfil da aspartato aminotransferase e alanina aminotransferase e a biometria do fígado de codornas poedeiras (Coturnix coturnix japonica) de 1 a 25 dias de idade. Avaliaram-se o peso vivo e o peso do fígado e as atividades das aspartato e alanina aminotransferases no fígado utilizando-se 90 codornas de 1 dia de idade. O delineamento experimental foi inteiramente casualizado com seis idades e cinco repetições, considerando cada animal uma unidade experimental. Aos 1,...

Atypical E2f functions are critical for pancreas polyploidization.

Science.gov (United States)

Matondo, Ramadhan B; Moreno, Eva; Toussaint, Mathilda J M; Tooten, Peter C J; van Essen, Saskia C; van Liere, Elsbeth A; Youssef, Sameh A; Bongiovanni, Laura; de Bruin, Alain

2018-01-01

The presence of polyploid cells in the endocrine and exocrine pancreas has been reported for four decades. In rodents, pancreatic polyploidization is initiated after weaning and the number of polyploid cells increases with age. Surprisingly the molecular regulators and biological functions of polyploidization in the pancreas are still unknown. We discovered that atypical E2f activity is essential for polyploidization in the pancreas, using an inducible Cre/LoxP approach in new-born mice to delete ubiquitously the atypical E2f transcription factors, E2f7 and E2f8. In contrast to its critical role in embryonic survival, conditional deletion of both of both atypical E2fs in newborn mice had no impact on postnatal survival and mice lived until old age. However, deficiency of E2f7 or E2f8 alone was sufficient to suppress polyploidization in the pancreas and associated with only a minor decrease in blood serum levels of glucose, insulin, amylase and lipase under 4 hours starvation condition compared to wildtype littermates. In mice with fewer pancreatic polyploid cells that were fed ad libitum, no major impact on hormones or enzymes levels was observed. In summary, we identified atypical E2fs to be essential for polyploidization in the pancreas and discovered that postnatal induced loss of both atypical E2fs in many organs is compatible with life until old age.

Atypical E2f functions are critical for pancreas polyploidization.

Directory of Open Access Journals (Sweden)

Ramadhan B Matondo

Full Text Available The presence of polyploid cells in the endocrine and exocrine pancreas has been reported for four decades. In rodents, pancreatic polyploidization is initiated after weaning and the number of polyploid cells increases with age. Surprisingly the molecular regulators and biological functions of polyploidization in the pancreas are still unknown. We discovered that atypical E2f activity is essential for polyploidization in the pancreas, using an inducible Cre/LoxP approach in new-born mice to delete ubiquitously the atypical E2f transcription factors, E2f7 and E2f8. In contrast to its critical role in embryonic survival, conditional deletion of both of both atypical E2fs in newborn mice had no impact on postnatal survival and mice lived until old age. However, deficiency of E2f7 or E2f8 alone was sufficient to suppress polyploidization in the pancreas and associated with only a minor decrease in blood serum levels of glucose, insulin, amylase and lipase under 4 hours starvation condition compared to wildtype littermates. In mice with fewer pancreatic polyploid cells that were fed ad libitum, no major impact on hormones or enzymes levels was observed. In summary, we identified atypical E2fs to be essential for polyploidization in the pancreas and discovered that postnatal induced loss of both atypical E2fs in many organs is compatible with life until old age.

E2F family members are differentially regulated by reversible acetylation

DEFF Research Database (Denmark)

Marzio, G; Wagener, C; Gutierrez, M I

2000-01-01

of the other E2F family members. Here we report that E2F-1, -2, and -3, but not E2F-4, -5, and -6, associate with and are acetylated by p300 and cAMP-response element-binding protein acetyltransferases. Acetylation occurs at three conserved lysine residues located at the N-terminal boundary of their DNA......The six members of the E2F family of transcription factors play a key role in the control of cell cycle progression by regulating the expression of genes involved in DNA replication and cell proliferation. E2F-1, -2, and -3 belong to a structural and functional subfamily distinct from those...

Taxation in France

CERN Document Server

HR Department

2016-01-01

Information regarding income tax in France. Request for additional information: social security number and personal details.   Some members of the personnel living in France have received a letter from the French tax authorities accompanied by a form, to be returned by 31 March 2016 at the latest, asking them to indicate their social security number and to confirm their personal details. As employed members of the CERN personnel are members of the Organization’s own health insurance scheme and do not participate in the French social security system, we recommend that you tick the box indicating that you do not have a social security number. We also advise you to specify in writing that, as an employed member of the CERN personnel, you do not participate in the French social security system especially by virtue of the 1970 agreement on social security between France and CERN: “Je ne suis pas soumis(e), en tant que fonctionnaire du CERN, à la sécurit&...

Sporadic-E and spread-F in high latitude region

International Nuclear Information System (INIS)

Tao, Kazuhiko

1974-01-01

The heretofore made morphological studies of sporadic-E and spread-F as the typical irregularities of electron density are reviewed. These phenomena have close correlation with other geophysical phenomena which occur in the atmosphere of superhigh altitude in high latitude region. Many of these phenomena occur from same causes. Although the quantitative data are insufficient, the sporadic-E and spread-F in high latitude region are supposed to be caused by the precipitating charged particles falling from magnetosphere. A system, which can observe such phenomena simultaneously using the measuring instruments carried by satellites in the atmosphere of high altitude over high latitude region, is desirable to solve such problems. In detail, the morphological study on sporadic-E obtained from the observation of vertically projected ionosphere and the morphological study on sporadic-E from the observation of forward scattering and slanting entrance are reviewed. The correlation of the occurrence frequency of sporadic-E with solar activity, geomagnetic activity and other phenomena was studied. The morphological study on spread-F occurrence is reviewed. The observation of the spread-F in high latitude region by the application of top side sounding is reviewed. The correlation of the sporadic-E and spread-F in high latitude region with other geophysical phenomena is discussed. Finally, the discrete phenomenon and the diffuse phenomenon are discussed too. (Iwakiri, K.)

39 CFR 121.1 - First-Class Mail.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false First-Class Mail. 121.1 Section 121.1 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] SERVICE STANDARDS FOR MARKET-DOMINANT MAIL PRODUCTS § 121.1 First-Class Mail. (a) For all intra-Sectional Center Facility (SCF) domestic...

Electronic Mail, a New Written-Language Register: A Study with French-Speaking Adolescents

Science.gov (United States)

Volckaert-Legrier, Olga; Bernicot, Josie; Bert-Erboul, Alain

2009-01-01

The aim of this study was to determine the extent to which the linguistic forms used by adolescents in electronic mail (e-mail) differ from those used in standard written language. The study was conducted in French, a language with a deep orthography that has strict, addressee-dependent rules for using second person personal pronouns (unfamiliar…

39 CFR 111.1 - Mailing Standards of the United States Postal Service, Domestic Mail Manual; incorporated by...

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Mailing Standards of the United States Postal Service, Domestic Mail Manual; incorporated by reference of regulations governing domestic mail services... the approval of the Director of the Federal Register.” In conformity with that provision, and with 39...

Electronic Mail, Privacy, and the Electronic Communications Privacy Act of 1986: Technology in Search of Law.

Science.gov (United States)

Samoriski, Jan H.; And Others

1996-01-01

Attempts to clarify the status of e-mail privacy under the Electronic Communications Privacy Act of 1986 (ECPA). Examines current law and the paucity of definitive case law. A review of cases and literature suggests there is a gap in the existing ECPA that allows for potentially abusive electronic monitoring and interception of e-mail,…

E-branding og e-marketing af 3F - et casestudie

OpenAIRE

Brødsgaard, Astrid Isabella; Celik, Nagihan; Johansen, Michelle Lyager

2014-01-01

This project is a case study of the e-branding and e-marketing of 3F, a worker’s union, with a focus on which effect their e-brand has on current and potential members, as well as how successful this e-brand is at attract-ing and keeping members. Some of the aspects explored are the importance of the e-brand’s appearance, the increasing expectations of the members as well as the union’s apparent quality and availability according to its members. This project is a case study of the e-brandi...

AVALIAÇÃO DA CV. CABERNET FRANC PARA ELABORAÇÃO DE VINHO TINTO EVALUATION OF CV. CABERNET FRANC TO ELABORATE RED WINE

Directory of Open Access Journals (Sweden)

Luiz Antenor RIZZON

2001-08-01

Full Text Available A uva Cabernet Franc, originária da região de Bordeaux, França, foi introduzida no Rio Grande do Sul através da Estação Agronômica de Porto Alegre. É utilizada para a elaboração de vinho tinto para ser consumido jovem, embora apresente aptidão para envelhecer. Face a sua importância, conduziu-se este trabalho com o objetivo de determinar as características agronômicas e enológicas da uva Cabernet Franc para elaboração de vinho tinto. Para isso, realizaram-se estudos para caracterizar o cacho, o mosto e o vinho tinto nas safras de 1987 a 1994. Os resultados obtidos evidenciaram que a cv. Cabernet Franc tem cacho médio, formado por bagas pequenas. O mosto possui teores de açúcar e de acidez adequados para vinificação. O vinho apresenta elevado teor de K e de álcoois superiores. No aspecto sensorial, apresenta cor vermelho-rubi, com reflexos violáceos quando jovem, e de intensidade variável em função das safras vitícolas. No olfato, apresenta aroma com notas vegetais e frutadas, que lembram pimentão e frutas vermelhas, respectivamente. Gustativamente, o vinho apresenta boa estrutura, equilíbrio e personalidade marcante.Cabernet Franc grape is originated from Bordeaux, France. It was introduced in the Serra Gaúcha region in the south of Brazil, by the Estação Agronômica the Porto Alegre, RS. It is used to elaborate young red wine, but it can be aged too. Due to the importance of Cabernet Franc, this work had the objective to determine its agronomic and winemaking characteristics. To achieve this purpose, variables related to the berries, clusters, must, and wine were performed from 1987 to 1994. The results showed that Cabernet Franc grapes have clusters of medium size and small berries. The must has adequate sugar and titratable acidity levels for vinification. The Cabernet Franc wine has a high concentration of K and higher alcohols. The sensory evaluation showed that it has a ruby color with violet reflexes when

Acidez na vinificação em tinto das uvas Isabel, Cabernet Sauvignon e Cabernet Franc

OpenAIRE

Rizzon Luiz Antenor; Miele Alberto

2002-01-01

A acidez é uma das características gustativas mais importantes dos vinhos e influencia sua estabilidade e coloração. Devido à insolubilização do ácido tartárico sob a forma de sais, a acidez titulável e o pH podem ser alterados durante a vinificação de acordo com o teor de potássio da uva. Este trabalho avaliou a evolução da acidez durante a vinificação de três cultivares de uvas tintas (Isabel - Vitis labrusca -, Cabernet Sauvignon e Cabernet Franc - Vitis vinifera) da Serra Gaúcha. Os vinho...

Transmission of F4+ E. coli in groups of early weaned piglets

NARCIS (Netherlands)

Geenen, P.L.; Döpfer, D.; Meulen, van der J.; Jong, de M.C.M.

2005-01-01

The aim of this study was to estimate transmission parameters of enterotoxigenic F4+ Escherichia coli F4 (F4+ E. coli) in groups of early weaned piglets with F4-receptor-positive (F4R+) and F4-receptor-negative piglets (F4R[minus sign]). Transmission of F4+ E. coli was quantified in four

A brain-computer interface controlled mail client.

Science.gov (United States)

Yu, Tianyou; Li, Yuanqing; Long, Jinyi; Wang, Cong

2013-01-01

In this paper, we propose a brain-computer interface (BCI) based mail client. This system is controlled by hybrid features extracted from scalp-recorded electroencephalographic (EEG). We emulate the computer mouse by the motor imagery-based mu rhythm and the P300 potential. Furthermore, an adaptive P300 speller is included to provide text input function. With this BCI mail client, users can receive, read, write mails, as well as attach files in mail writing. The system has been tested on 3 subjects. Experimental results show that mail communication with this system is feasible.

CORPORATE E-MAIL SERVICE GOOGLE APPS AS AN INSTRUMENT OF ACTIVITY OF ORGANIZATIONAL-EDUCATIONAL UNITS OF THE HIGHER EDUCATIONAL INSTITUTION

OpenAIRE

Кarpenko А.

2017-01-01

The advantages of usage of cloud technologies, particularly, of Gmail service Google Apps in work of organizational-educational units of higher educational institutions are analyzed in this work. The main accents are put concerning usage of corporate e-mail Gmail service Google Apps, with the help of which informational-analytical support of activity of organizational-educational units of the University is provided. The author of the publication underlines key advantages of Gmail and analyses...

E2F-1-Induced p53-independent apoptosis in transgenic mice

DEFF Research Database (Denmark)

Holmberg, Christian Henrik; Helin, K.; Sehested, M.

1998-01-01

The E2F transcription factors are key targets for the retinoblastoma protein, pRB. By inactivation of E2Fs, pRB prevents progression to the S phase. To test proliferative functions of E2F, we generated transgenic mice expressing human E2F-1 and/or human DP-1. When the hydroxymethyl glutaryl...... involving increased apoptosis in the germinal epithelium. This effect was potentiated by simultaneous overexpression of DP-1. Testicular atrophy as a result of overexpression of E2F-1 and DP-1 is independent of functional p53, since p53-nullizygous transgenic mice overexpressing E2F-1 and DP-1 also suffered...

E2F4 is required for early eye patterning.

Science.gov (United States)

Ruzhynsky, Vladimir A; Furimsky, Marosh; Park, David S; Wallace, Valerie A; Slack, Ruth S

2009-01-01

Increasingly, studies reveal novel functions for cell cycle proteins during development. Here, we investigated the role of E2F4 in eye development. E2F4-deficient mouse embryos exhibit severe early eye patterning defects, which are evident from embryonic day 11.5 and characterized by aberrant shape of the optic cup, coloboma as well as abnormal eye pigmentation. Loss of E2F4 is associated with proximal-distal patterning defects in the optic vesicle. These defects are characterized by the expansion of optic stalk marker gene expression to the optic cup and reduced expression of ventral optic cup markers. These defects are associated with a split of Shh expression domain at the ventral midline of the forebrain and expansion of the Shh activity into the ventral optic cup. Despite these patterning defects, early neuronal differentiation and Shh expression in the retina are not affected by E2F4 deletion. Overall, the results of our studies show a novel role of E2F4 in the early eye development. 2009 S. Karger AG, Basel.

Quaternary climate modulation of Pb isotopes in the deep Indian Ocean linked to the Himalayan chemical weathering

Digital Repository Service at National Institute of Oceanography (India)

Wilson, D.J.; Galy, A.; Piotrowski, A.M.; Banakar, V.K.

-lès-Nancy, France d C a Ar Re Re Ac Av Ed Ke In Ga Hi bo lea m 1. th sp ev in w Ri th * ria ht 00SIR-National Institute of Oceanography, Dona Paula, Goa, 403 004, India r t i c l e i n f o a b s t r a c t ticle history: ceived 23 December 2014 ceived in revised... orogen, via e Ganges and Brahmaputra rivers, provides a significant source of Corresponding author at: Department of Earth Science and Engineering, Impe- l College London, London SW7 2AZ, United Kingdom. Tel.: +44 20 7594 6463. E-mail address: david...

The globalization of big French firms: the case of Electricite de France; L'internationalisation des grandes entreprises francaises: le cas d'Electricite de France

Energy Technology Data Exchange (ETDEWEB)

Ailleret, F. [Electricite de France (EDF), 75 - Paris (France)

1999-11-01

A national monopoly created more than 50 years ago, Electricite de France has become so international that it is a major player in the world electricity market. In mid-1999, EdF had already invested about 4,5 billion euro in approximately 20 countries in Europe, Latin America, Africa and Asia. The electric utility is becoming even more involved in globalization, its objective being to make 30-35 % of sales outside France by 2005. (authors)

E1A-dependent trans-activation of the human MYC promoter is mediated by the E2F factor

International Nuclear Information System (INIS)

Hiebert, S.W.; Lipp, M.; Nevins, J.R.

1989-01-01

E2F is a cellular transcription factor that binds to two sites in the adenovirus E2 promoter. Previous experiments have implicated E2F in the E1A-dependent transactivation of the E2 gene since levels of active E2F increase markedly during adenovirus infection in parallel with the increase in E2 transcription, and an E2F binding site can confer E1A inducibility to a heterologous promoter. Here the authors show that E2F binds to two sequence elements within the P2 promoter of the human MYC gene which are within a region that is critical for promoter activity. The MYC promoter can be trans-activated in an E1A-dependent manner and site-directed mutagenesis demonstrates that these E2F elements are essential for trans-activation. Finally, they also find that adenovirus infection of quiescent cells results in a stimulation of the endogenous MYC gene. They conclude that the activation of the E2F factor, which is likely responsible for the activation of viral E2 transcription, is also responsible for the E1A-dependent induction of MYC transcription

Gaz de France and cogeneration: a story which goes on; Gaz de France et la cogeneration: une histoire qui se poursuit

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-09-15

This document presents the principle of natural gas cogeneration (gas turbine and gas engine) and gives a general overview of the cogeneration market in France since 1991 and up to 2001 (development factors, results). The perspectives and opportunities of cogeneration are analyzed with respect to the development of new technologies like fuel cells (principle, advantages and future) and to the future energy markets. Follows a compilation and an analysis of French regulation texts about cogeneration systems, their connection to the power grid, and the tariffs of electricity re-purchase by Electricite de France (EdF). (J.S.)

France under a microscope - Nuclear power in France

International Nuclear Information System (INIS)

2008-01-01

The first French nuclear power plant was built in 1956, but it was only after the 1970's oil shock that nuclear power gained an important place in the French energy sector. Planning Act 2005-781 of 13 July 2005 laying down French energy policy orientations confirmed that nuclear energy was to remain the primary source of electricity supply in France. The Act also encourages diversification of sources of electricity production through renewable energies (wind power, biomass) and the security of electricity supply from oil, gas and coal. Nuclear energy accounted for 78.4% of electricity production in France in 2006. French nuclear capacity includes 58 pressurized water reactors (PWRs) that produced 450 billion nuclear kilowatt-hours (kWh) in 2006, i.e. 78.4% of total electricity production which is of 574 billion kWh. The lifetime of a third of currently operating nuclear plants will end in around 2020 and, with a view to the renewal of its nuclear capacity, France is about to deploy new-generation reactors that meet requirements in terms of production, environmental protection and enhanced nuclear safety. In April 2007, France started building a third-generation EPR reactor at Flamanville in the Manche Department. The EPR is to be operational by 2012. France is also devoting research programmes to fourth generation reactor technology with a view to those reactors being operational by 2040. There are a number of reasons for choosing nuclear power: it enables France to ensure its national energy independence (France imports less than 50% of its energy resources) and environmental protection (France is one of the European countries which emits the least greenhouse gases) at a stable and competitive price. Decree 2008-378 of 21 April 2008 instituted a council on nuclear policy presided by the President of the Republic. The council will define the broad lines of nuclear policy and monitor their implementation, particularly with regard to exports and international

Filmer le travail dans un train postal. À propos de Night Mail Filming work in a mail train. A study of Night Mail Filmar el trabajo en un tren de correos. Acerca de Night Mail

Directory of Open Access Journals (Sweden)

Pierre Maillot

2013-03-01

telecommunications at a time (1936 when the field was going through a great deal of change. Because of this, the film can be analysed as a reflection on one institution, on several institutions, on their organisation and on employees, without which work would be impossible. The main goal of the present article is to offer sociologists interested in the sociology of film a number of elements allowing them to grasp the conceptual possibilities associated with film writing.Night Mail, documental de cortometraje producido en 1936 por la Unidad de filmes de GPO (General Post Office, Oficina general de correos del ministerio de Correos del Reino Unido, describe el trabajo de clasificación del correo en los transportes ferroviarios nocturnos. Para el organismo gubernamental que lo produjo, se trataba ante todo de una película sobre el Correo y sus trabajadores, incluidos quienes laboraban en el terreno, a bordo de los trenes o en las oficinas. La película, por necesidad, tuvo que abordar también la labor de la compañía de ferrocarriles que transportaba el correo, y por lo tanto el trabajo de los ferrocarrileros; de todos los ferrocarrileros: los que manejaban las máquinas, los que trabajaban en las vías, en las estaciones a lo largo del trayecto, los de las oficinas que se encargaban de los enlaces por teléfono, vía morse y a través de todas las telecomunicaciones, que en esa época estaban en pleno desarrollo (recordemos que la acción se sitúa en 1936. De tal forma que esa película se convirtió en una reflexión sobre la institución, las instituciones, su organización y su colaboración, sin la cual no hay trabajo posible. Este artículo tiene como objetivo central proponer a los sociólogos interesados en la sociología fílmica algunos elementos para comprender las posibilidades conceptuales de la escritura fílmica.

Automatic EEG-assisted retrospective motion correction for fMRI (aE-REMCOR).

Science.gov (United States)

Wong, Chung-Ki; Zotev, Vadim; Misaki, Masaya; Phillips, Raquel; Luo, Qingfei; Bodurka, Jerzy

2016-04-01

Head motions during functional magnetic resonance imaging (fMRI) impair fMRI data quality and introduce systematic artifacts that can affect interpretation of fMRI results. Electroencephalography (EEG) recordings performed simultaneously with fMRI provide high-temporal-resolution information about ongoing brain activity as well as head movements. Recently, an EEG-assisted retrospective motion correction (E-REMCOR) method was introduced. E-REMCOR utilizes EEG motion artifacts to correct the effects of head movements in simultaneously acquired fMRI data on a slice-by-slice basis. While E-REMCOR is an efficient motion correction approach, it involves an independent component analysis (ICA) of the EEG data and identification of motion-related ICs. Here we report an automated implementation of E-REMCOR, referred to as aE-REMCOR, which we developed to facilitate the application of E-REMCOR in large-scale EEG-fMRI studies. The aE-REMCOR algorithm, implemented in MATLAB, enables an automated preprocessing of the EEG data, an ICA decomposition, and, importantly, an automatic identification of motion-related ICs. aE-REMCOR has been used to perform retrospective motion correction for 305 fMRI datasets from 16 subjects, who participated in EEG-fMRI experiments conducted on a 3T MRI scanner. Performance of aE-REMCOR has been evaluated based on improvement in temporal signal-to-noise ratio (TSNR) of the fMRI data, as well as correction efficiency defined in terms of spike reduction in fMRI motion parameters. The results show that aE-REMCOR is capable of substantially reducing head motion artifacts in fMRI data. In particular, when there are significant rapid head movements during the scan, a large TSNR improvement and high correction efficiency can be achieved. Depending on a subject's motion, an average TSNR improvement over the brain upon the application of aE-REMCOR can be as high as 27%, with top ten percent of the TSNR improvement values exceeding 55%. The average

The E2F2 transcription factor sustains hepatic glycerophospholipid homeostasis in mice.

Directory of Open Access Journals (Sweden)

Eduardo N Maldonado

Full Text Available Increasing evidence links metabolic signals to cell proliferation, but the molecular wiring that connects the two core machineries remains largely unknown. E2Fs are master regulators of cellular proliferation. We have recently shown that E2F2 activity facilitates the completion of liver regeneration after partial hepatectomy (PH by regulating the expression of genes required for S-phase entry. Our study also revealed that E2F2 determines the duration of hepatectomy-induced hepatic steatosis. A transcriptomic analysis of normal adult liver identified "lipid metabolism regulation" as a major E2F2 functional target, suggesting that E2F2 has a role in lipid homeostasis. Here we use wild-type (E2F2+/+ and E2F2 deficient (E2F2-/- mice to investigate the in vivo role of E2F2 in the composition of liver lipids and fatty acids in two metabolically different contexts: quiescence and 48-h post-PH, when cellular proliferation and anabolic demands are maximal. We show that liver regeneration is accompanied by large triglyceride and protein increases without changes in total phospholipids both in E2F2+/+ and E2F2-/- mice. Remarkably, we found that the phenotype of quiescent liver tissue from E2F2-/- mice resembles the phenotype of proliferating E2F2+/+ liver tissue, characterized by a decreased phosphatidylcholine to phosphatidylethanolamine ratio and a reprogramming of genes involved in generation of choline and ethanolamine derivatives. The diversity of fatty acids in total lipid, triglycerides and phospholipids was essentially preserved on E2F2 loss both in proliferating and non-proliferating liver tissue, although notable exceptions in inflammation-related fatty acids of defined phospholipid classes were detected. Overall, our results indicate that E2F2 activity sustains the hepatic homeostasis of major membrane glycerolipid components while it is dispensable for storage glycerolipid balance.

A comparative analysis of mail and internet surveys

Science.gov (United States)

Benjamin D. Poole; David K. Loomis

2010-01-01

Th e field of survey research is constantly evolving with the introduction of new technologies. Each new mini-revolution brings criticism about the accuracy of the new survey method. The latest development in the survey research field has been increased reliance on Internet surveys. This paper compares data collected through a mixed-mode (mail and Internet) survey of...

39 CFR 111.2 - Availability of the Mailing Standards of the United States Postal Service, Domestic Mail Manual.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Availability of the Mailing Standards of the United States Postal Service, Domestic Mail Manual. 111.2 Section 111.2 Postal Service UNITED STATES POSTAL SERVICE POST OFFICE SERVICES [DOMESTIC MAIL] GENERAL INFORMATION ON POSTAL SERVICE § 111.2...

EdF: high tension(s) metamorphosis

International Nuclear Information System (INIS)

Roussely, F.; Arnoux, P.; Baritault, A.; Alto, P.; Castets, C.; Secondi, J.

2003-01-01

Electricite de France, the French electric utility, has to face a formidable mutation. The deregulation of the power market will lead to a social, commercial, judicial, financial and international 'big-bang'. The company has been weakened by disappointing results and by an embarrassing running into debts. This dossier analyzes the consequences of the deregulation of the French power market on the future evolution of EdF. It includes the analysis made by a French economist, E. Cohen, an interview and a portrait of F. Roussely, head of EdF, a presentation of Easenergy, a start-up of EdF which makes partnerships with US energy-related companies, the worries of EdF's employees and the redistribution of the syndicates power inside the company, the controversy around EdF's 2002 results and the points that remained in the shade, EdF's European competitors and the progressive opening of the French power market, EDF's production tool and its availability (58 nuclear reactors, 538 hydroelectric power plants and 26 thermal power plants), the costly foreign markets strategy of EdF and the under-capitalization of the company. (J.S.)

78 FR 12234 - Promotions and Incentive Programs for First-Class Mail and Standard Mail

Science.gov (United States)

2013-02-22

... No. R2013-1) on October 11, 2012 to offer six new promotions in 2013 and the PRC approved the 2013... Promotional Programs The six promotional programs, in calendar order are: 1. Direct Mail Mobile Coupon and... preparer in the by/for fields. Full-service mailings are limited to 9,999 pieces if submitted via Postal...

Continuous A.E. monitoring of nuclear systems: some feasibility studies now in-progress in France

International Nuclear Information System (INIS)

Roget, J.; Germain, J.L.

1986-01-01

Continuous A.E. monitoring of Nuclear systems can give some unique information about abnormal behaviour (leak appearance...) or crack initiation or propagation. Some feasibility studies have been undertaken in France in this field and this paper presents the results we have got in two cases. The study showed that an A.E. surveillance of pressurized safety valves indicates the appearance or the presence of a leak. Functioning noise is not a problem in this case. Secondly a large study have been undertaken to test the resistance of the pipe inner sleeve to thermal fatigue. An A.E. monitoring showed that it is possible to separate A.E. due to Crack extension from other signals by a location method in spite of high noise level. A.E. seems applicable for continuous monitoring. So, complementary tests are in progress to confirm and improve these results

The Development and Implementation of a Global Network for Eurasia Educational Service Using Electronic Mail.

Science.gov (United States)

Algee, Alan

The purpose of this study was to choose an appropriate network provider for educational consultants and to develop and implement the network at Eurasia Educational Services (EES) using electronic mail (e-mail). The following eight steps were undertaken: literature review, scanning and selecting of provider criteria, decision-making, participant…

Using Electronic Mail to Conduct Survey Research.

Science.gov (United States)

Thach, Liz

1995-01-01

Describes public and private online networks and the characteristics of electronic mail. Reviews the literature on survey research conducted via electronic mail, and examines the issues of design, implementation, and response. A table displays advantages and disadvantages of electronic mail surveys. (AEF)

Electronic Mail in the Library: A Perspective.

Science.gov (United States)

Whitaker, Becki

1989-01-01

Provides an overview of electronic mail in libraries. Topics discussed include general business applications; interlibrary loan; acquisition and claims systems; document delivery; complete text journal databases; reference requests and answers; obstacles to electronic mail usage; telecommunications; cost factors; and the impact of voice mail and…

Impact of Performance Feedback Delivered via Electronic Mail on Preschool Teachers' Use of Descriptive Praise

Science.gov (United States)

Hemmeter, Mary Louise; Snyder, Patricia; Kinder, Kiersten; Artman, Kathleen

2011-01-01

We examined the effects of a professional development intervention that included data-based performance feedback delivered via electronic mail (e-mail) on preschool teachers' use of descriptive praise and whether increased use of descriptive praise was associated with changes in classroom-wide measures of child engagement and challenging behavior.…

77 FR 28259 - Mailings of Lithium Batteries

Science.gov (United States)

2012-05-14

... POSTAL SERVICE 39 CFR Part 111 Mailings of Lithium Batteries AGENCY: Postal Service TM . ACTION... international mailing of lithium batteries and devices containing lithium batteries. This prohibition also extends to the mailing of lithium batteries to and from an APO, FPO, or DPO location. However, this...

Simulating Policy Processes through Electronic Mail.

Science.gov (United States)

Flynn, John P.

1987-01-01

Focuses on the use of electronic mail for teaching and learning about social welfare policy processes and compares electronic mail as a simulation medium to more structured computer applications. (Author)

Assessment of the use level of direct mail in the V4 countries

Directory of Open Access Journals (Sweden)

Ľudmila Nagyová

2009-01-01

Full Text Available The aim is to assess the possibilities of future developments of Direct Marketing in the Visegrad group. Particular attention is paid to the fact that even when there is a single political grouping of states, which between them reported psychological closeness, there are differences between them, to be taken into account. Significant differences are primarily in consumer attitudes and preferences, their purchasing decisions as well as acceptance of the various tools of communication mix.Direct Marketing is form of marketing communication aimed on exact selection of target group and its effective addressing. Contrary to the Mass Marketing, each customer is addressed individually and directly, and databases of potential or regular customers are used. One form of Direct Marketing is Direct Mail. It is the oldest and most advanced tool of Direct Marketing. Also called mailing, it is the most important tool of Direct Marketing.The country with the highest amount of delivered mailings is Czech Republic. Up to 82% of respondents indicated that Direct Mail receives often or very often. In Slovak Republic, Poland and the Czech Republic, more than half of respondents read the received mailings only occasionally. Significantly overwhelming majority of Slovaks, Czechs and Poles responds to the delivered mailings by checking out the sender’s web site firstly, or establishing the contact via e-mail. Hungarian respondents prefer answer sheet the most.

Transcriptional regulation of human RANK ligand gene expression by E2F1

International Nuclear Information System (INIS)

Hu Yan; Sun Meng; Nadiminty, Nagalakshmi; Lou Wei; Pinder, Elaine; Gao, Allen C.

2008-01-01

Receptor activator of nuclear factor kappa B ligand (RANKL) is a critical osteoclastogenic factor involved in the regulation of bone resorption, immune function, the development of mammary gland and cardiovascular system. To understand the transcriptional regulation of RANKL, we amplified and characterized a 1890 bp 5'-flanking sequence of human RANKL gene (-1782 bp to +108 bp relative to the transcription start site). Using a series of deletion mutations of the 1890 bp RANKL promoter, we identified a 72 bp region (-172 to -100 bp) mediating RANKL basal transcriptional activity. Sequence analysis revealed a putative E2F binding site within this 72 bp region in the human RANKL promoter. Overexpression of E2F1 increased RANKL promoter activity, while down-regulation of E2F1 expression by small interfering RNA decreased RANKL promoter activity. RT-PCR and enzyme linked immunosorbent assays (ELISA) further demonstrated that E2F1 induced the expression of RANKL. Electrophoretic gel mobility shift assays (EMSA) and antibody competition assays confirmed that E2F1 proteins bind to the consensus E2F binding site in the RANKL promoter. Mutation of the E2F consensus binding site in the RANKL promoter profoundly reduced the basal promoter activity and abolished the transcriptional modulation of RANKL by E2F1. These results suggest that E2F1 plays an important role in regulating RANKL transcription through binding to the E2F consensus binding site

E2F1 transcription is induced by genotoxic stress through ATM/ATR activation.

Science.gov (United States)

Carcagno, Abel L; Ogara, María F; Sonzogni, Silvina V; Marazita, Mariela C; Sirkin, Pablo F; Ceruti, Julieta M; Cánepa, Eduardo T

2009-05-01

E2F1, a member of the E2F family of transcription factors, plays a critical role in controlling both cell cycle progression and apoptotic cell death in response to DNA damage and oncogene activation. Following genotoxic stresses, E2F1 protein is stabilized by phosphorylation and acetylation driven to its accumulation. The aim of the present work was to examine whether the increase in E2F1 protein levels observed after DNA damage is only a reflection of an increase in E2F1 protein stability or is also the consequence of enhanced transcription of the E2F1 gene. The data presented here demonstrates that UV light and other genotoxics induce the transcription of E2F1 gene in an ATM/ATR dependent manner, which results in increasing E2F1 mRNA and protein levels. After genotoxic stress, transcription of cyclin E, an E2F1 target gene, was significantly induced. This induction was the result of two well-differentiated effects, one of them dependent on de novo protein synthesis and the other on the protein stabilization. Our results strongly support a transcriptional effect of DNA damaging agents on E2F1 expression. The results presented herein uncover a new mechanism involving E2F1 in response to genotoxic stress.

A proposed evolution for the Italian certified electronic mail system

OpenAIRE

Buzzi, Marina; Ferrucci, Luca; Francesco, Gennai; Petrucci, Claudio

2016-01-01

One the main objective of the European Commission is to innovate and bring ICT to its full potential in any sector, including eGovernment, eCommerce, and eHealth services. Certified Electronic Mail (CEM) systems of Member States are currently not interoperable, thus impacting on economic growth and competitiveness. The paper investigates the use of the DNSSec technology as a technological evolution of the Italian CEM System and the first step towards interoperability and adherence to internat...

垃圾邮件防止法之探讨%An Analysis of the Draft of Protection in Spam E-mails and Filters

Institute of Scientific and Technical Information of China (English)

曾胜珍

2013-01-01

Modern people use e-mail to connect a majority of life , even busi-ness, including customer and vendor communication , marketing, and filing official documents .The most recent development , mass electronic mailing-known in the computer industry vernacular as “spam”—allows businesses to contact millions of potential customers , large numbers of them can be extremely inconvenient , with al-most no cost per message .When we discover that our most recent e-mails were not delivered to recipients by using a major Internet Service Provider (“ISP”) , be-cause we were recently listed on an automated block list as a sender of unwanted bulk commercial e-mail (“spam”) .The most efficient approach for a sender im-properly included on a block list or a spam filter is to request removal directly from that list or filter .The paper will provide the suggestions of proposed amendments in the future legislature .%因特网的发展与便利形成现代社会中不可或缺的存在，电子邮件的便利跨越时空的限制，使得人与人之间的联系紧密维护，然而垃圾邮件（ Junk E－mails）却同时造成使用人相当的困扰，不但增加层层过滤信件的时间，也引发部分正常信件经过封锁名单（ Block Lists ）及垃圾邮件清除器（ Spam Filters ）的使用，反而被归类到垃圾邮件的分类。本文建议应考虑垃圾邮件发信人查缉不易与变换位置迅速的缺点，参考美国经验并检视美国法规制度与实务判决等方面，再衡量既有法制解决此类问题将面临的困难与障碍，从而提出设立新法的建议与内容，希冀能为垃圾邮件防止法提供省思与依据。

Induction of DNA synthesis and apoptosis are separable functions of E2F-1

DEFF Research Database (Denmark)

Phillips, A C; Bates, S; Ryan, K M

1997-01-01

The family of E2F transcription factors have an essential role in mediating cell cycle progression, and recently, one of the E2F protein family, E2F-1, has been shown to participate in the induction of apoptosis. Cooperation between E2F and the p53 tumor suppressor protein in this apoptotic...... response had led to the suggestion that cell cycle progression induced by E2F-1 expression provides an apoptotic signal when placed in conflict with an arrest to cell cycle progression, such as provided by p53. We show here that although apoptosis is clearly enhanced by p53, E2F-1 can induce significant...... apoptosis in the absence of p53. Furthermore, this apoptotic function of E2F-1 is separable from the ability to accelerate entry into DNA synthesis. Analysis of E2F-1 mutants indicates that although DNA-binding is required, transcriptional transactivation is not necessary for the induction of apoptosis by E...

The globalization of big French firms: the case of Electricite de France

International Nuclear Information System (INIS)

Ailleret, F.

1999-01-01

A national monopoly created more than 50 years ago, Electricite de France has become so international that it is a major player in the world electricity market. In mid-1999, EdF had already invested about 4,5 billion euro in approximately 20 countries in Europe, Latin America, Africa and Asia. The electric utility is becoming even more involved in globalization, its objective being to make 30-35 % of sales outside France by 2005. (authors)

Estimating transmission parameters of F4 + E. coli for F4-receptor-positive and -negative piglets: one-to-one transmission experiment

NARCIS (Netherlands)

Geenen, P.L.; Meulen, van der J.; Bouma, A.; Jong, de M.C.M.

2004-01-01

F4+ Escherichia coli is an important agent of post-weaning diarrhoea in piglets. Piglets that express an adhesion site for F4+ E. coli in their small intestine (F4R+) shed higher numbers of F4+ E. coli than piglets lacking this site (F4R[minus sign]). We hypothesized that F4R+ piglets are more

Estudo de usuários de web e-mail: a busca pela informação através dos portais eletrônicos

Directory of Open Access Journals (Sweden)

Gabrielle Francinne de Souza Carvalho

2009-04-01

Full Text Available Este trabalho tem como objetivo analisar dois tipos de abordagem – tradicional e alternativa – utilizadas nos estudos de usuário. Para isso, adotou-se os instrumentos de coleta de dados adequados a cada tipo de abordagem: o questionário, na abordagem tradicional, e a entrevista, na abordagem alternativa. Percebeu-se que o primeiro não permite estabelecer um diálogo mais estreito com o usuário, devido à limitação das respostas, uma vez que já estavam definidas. Já a entrevista possibilitou conhecer com mais detalhes as necessidades informacionais de cada usuário e como se efetiva seu processo de busca e uso. Assim, verificou-se através de quais portais eletrônicos os usuários buscam essa informação, procurando entender se esses portais são os mesmos que possuem vinculados os provedores de seus e-mails, visto que esses portais eletrônicos deveriam possibilitar também o suprimento de suas necessidades informacionais. Concluiu-se que a maioria dos sujeitos desta pesquisa não utiliza, por diversos motivos, seus provedores de e-mail principal para buscar informação. A partir dos resultados, observou-se que a primeira abordagem não reconhece as necessidades individuais de cada usuário, limitando-se à objetividade de um tratamento estatístico. Em contrapartida, a segunda abordagem reconhece a subjetividade e as necessidades desses usuários.

The history of tidal power in France

International Nuclear Information System (INIS)

Banal, M.

1997-01-01

The first known use of tidal power in France concerns the tidal mills in general use during the Middle Age along the French coasts. The first research studies of tidal power plants started at the end of the first world war but it is only in 1940 with the stimulus of Robert Gibrat that was created the Research Society for the use of Tides and the Rance plant project. In 1946, Electricite de France (EdF) started again the studies of this company for a greater size project in the Chausey archipelago which was abandoned for the benefit of the Rance project in the 1960's. The start up of the plant took place in 1967 but the other projects were abandoned during the 1980's. This short paper recalls the historical aspects of the development of tidal power in France and focusses on the research and development studies and on the economical, political and legal factors that led to retain the Rance project among others proposed. (J.S.)

Take control of Apple Mail in Leopard

CERN Document Server

Kissell, Joe

2009-01-01

Go under the hood with new (and old) features in Apple Mail in Leopard! Are you using Apple Mail in Leopard effectively? In this book, completely updated from its previous Panther and Tiger editions, author Joe Kissell provides comprehensive guidance, with a focus on new and updated features. You'll learn how to use and customize the Mail window, control the size and styling of incoming messages, and make rules to move messages into different mailboxes automatically. The book covers outgoing mail, showing you smart ways to address messages, send attachments, and send HTML-based messages. Bu

You've got mail! An examination of a statewide direct-mail marketing campaign to promote deceased organ donor registrations.

Science.gov (United States)

Quick, Brian L; LaVoie, Nicole R; Morgan, Susan E; Bosch, Dave

2015-11-01

This study extends previous direct-mail campaigns by evaluating the effectiveness of a marketing campaign promoting organ donation message strategies from the vantage point of organ donors, organ recipients, individuals on the waiting list, or a combination of these three frames. Illinois residents were randomly assigned to one of four organ donation brochures disseminated via U.S. postal mail. Registrations occurred via the Internet and U.S. postal mail. Individuals register at a greater rate following exposure to the combination framed message compared to organ donor, organ recipient, and waiting list narratives. The campaign revealed that individuals are more likely to register via U.S. postal mail than the Internet. Direct-mail marketing efforts were shown to be an effective approach to promote organ and tissue donation registrations. The results demonstrated a preference for the combination framed brochure. The results are discussed with an emphasis on the practical implications of utilizing direct-mail marketing efforts to promote organ donation among young adults. © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Une activité politique féminine conservatrice avant le droit de suffrage en France et en Italie. Sociohistoire de la politisation des femmes catholiques au sein de la Ligue patriotique des Françaises (1902-1933 et de l’Unione fra le donne cattoliche d’Italia (1909-1919.

Directory of Open Access Journals (Sweden)

Magali Della Sudda

2010-01-01

Full Text Available Cette recherche historique qui croise les apports des études de genre, de la science politique et de la sociologie religieuse met en lumière la façon singulière dont les militantes d’action féminine catholique sont venues à la politique en France et en Italie durant les premières décennies du XXe siècle. Deux associations catholiques féminines de masse ont fait l’objet de cette analyse comparée : la Ligue patriotique des Françaises active de 1902 à 1933 et l’Unione fra le donne cattoliche d’I...

CONSUMER DEMAND FOR AND ATTITUDES TOWARD ALTERNATIVE BEEF LABELING STRATEGIES IN FRANCE, GERMANY, AND THE UK

OpenAIRE

Roosen, Jutta; Lusk, Jayson L.; Fox, John A.

2001-01-01

A wide array of food safety scares and breakdowns have led to loss of consumer confidence in the quality and safety of beef products. To counteract such concerns, firms and regulators have the ability to utilize brands or labels to signal quality. Utilizing a mail survey in France, Germany, and the United Kingdom, we analyzed consumer preferences for alternative beef labeling strategies. Using an ordered probit model and a double bounded logit model, we estimate consumer preferences for alter...

The RB/E2F pathway and regulation of RNA processing

Energy Technology Data Exchange (ETDEWEB)

Ahlander, Joseph [Department of Molecular and Cellular Biology, 1007 East Lowell Street, University of Arizona, Tucson, AZ 85721 (United States); Bosco, Giovanni, E-mail: gbosco@email.arizona.edu [Department of Molecular and Cellular Biology, 1007 East Lowell Street, University of Arizona, Tucson, AZ 85721 (United States)

2009-07-03

The retinoblastoma tumor suppressor protein (RB) is inactivated in a majority of cancers. RB restricts cell proliferation by inhibiting the E2F family of transcription factors. The current model for RB/E2F function describes its role in regulating transcription at gene promoters. Whether the RB or E2F proteins might play a role in gene expression beyond transcription initiation is not well known. This review describes evidence that points to a novel role for the RB/E2F network in the regulation of RNA processing, and we propose a model as a framework for future research. The elucidation of a novel role of RB in RNA processing will have a profound impact on our understanding of the role of this tumor suppressor family in cell and developmental biology.

New information technology and communication in health care: using e-mail for marketing services

Directory of Open Access Journals (Sweden)

Jorge Iván Martínez Espitia

2015-01-01

Full Text Available Research that was conducted was aimed to determine their use of e-mail independent health professionals. Email is one of the tools of information and communication that has shown great versatility and efciency as a means to improve the relationship between those who provide services or sell products users. Good communication is essential to keep current customers and attract new business prospects. To achieve the objective of the research a survey that measured the perception and use of email marketing by independent health professionals was conducted in Colombia. Four variables, including tenure email account, receiving these email accounts marketing of products or services, read marketing emails and use by marketing professionals were measured with email. The result of this study showed that independent health professionals in Colombia are familiar with this type of marketing. Generally interested incorporate it as one of your marketing tools, but do not know how to do this activity, which is described in a simple way how to do a marketing campaign with the use of emails to the users of health services.

New information technology and communication in health care: using e-mail for marketing services

Directory of Open Access Journals (Sweden)

Jorge Iván Martínez Espitia

2014-07-01

Full Text Available Research that was conducted was aimed to determine their use of e-mail independent health professionals. Email is one of the tools of information and communication that has shown great versatility and efciency as a means to improve the relationship between those who provide services or sell products users. Good communication is essential to keep current customers and attract new business prospects. To achieve the objective of the research a survey that measured the perception and use of email marketing by independent health professionals was conducted in Colombia. Four variables, including tenure email account, receiving these email accounts marketing of products or services, read marketing emails and use by marketing professionals were measured with email. The result of this study showed that independent health professionals in Colombia are familiar with this type of marketing. Generally interested incorporate it as one of your marketing tools, but do not know how to do this activity, which is described in a simple way how to do a marketing campaign with the use of emails to the users of health services.

76 FR 17787 - Market Dominant Negotiated Service Agreement (NSA) for First-Class Mail and Standard Mail

Science.gov (United States)

2011-03-31

... POSTAL SERVICE 39 CFR Part 111 Market Dominant Negotiated Service Agreement (NSA) for First- Class....1, to establish a new Negotiated Service Agreement (NSA) Market Dominant product for First-Class... Gifford at 202-268-8082. SUPPLEMENTARY INFORMATION: This new NSA for First-Class Mail and Standard Mail is...

Data Leakage Prevention: E-Mail Protection via Gateway

Science.gov (United States)

Kaur, Kamaljeet; Gupta, Ishu; Singh, Ashutosh Kumar

2018-01-01

Protection of digital assets and intellectual property is becoming a challenge for most of the companies. Due to increasing availability of database services on internet, data may be insecure after passing through precarious networks. To protect intellectual property (IP) is a major concern for today's organizations, because a leakage that compromises IP means, sensitive information of a company is in the hands of biggest competitors. Electronic information processing and communication is replacing paper in many applications increasingly. Instead of paper, an email is being used for communication at workplace and from social media logins to bank accounts. Nowadays an email is becoming a mainstream business tool. An email can be misused to leave company’s sensitive data open to compromise. So, it may be of little surprise that attacks on emails are common. So, here we need an email protection system (EPS) that will protect information to leave organization via mail. In this paper, we developed an algorithm that will offer email protection via gateway during data transfer. This algorithm matches the patterns with the keywords stored in the database and then takes the actions accordingly to protect the data. This paper describes why email protection is important? How companies can protect their confidential information from being leaked by insiders.

Mail Service

CERN Multimedia

TS-FM Group

2004-01-01

Tuesday 19 October 2004 Please note that the distribution and collection of mail are likely to be disrupted on Tuesday, October 19, 2004, because of traffic and other restrictions enforced on that day in connection with CERN's fiftieth anniversary celebrations. The service may be completely interrupted in certain areas. Group TS-FM, Tel. 77551

Soviet-France cooperative study of the solar corona

International Nuclear Information System (INIS)

Vsekhvsyatskij, S.K.; Dzyubenko, N.I.; Ivanchuk, V.I.; Popov, O.S.; Rubo, G.A.; Kuchmij, S.; Kuchmij, O.; Shtel'makher, G.

1981-01-01

The study continues the investigations on the solar corona performed according to the program of the Soviet-France experiment ''The white corona dynamics'' during total solar eclipses on July 10 1972 and June 30, 1973 by the expeditions of Kiev University and Paris Astrophysical Institute. The results of the study of eclipse negatives obtained on June 30 1973 in Africa are given. On the basis of new methods of photometry and colorimetry using star images up to 8.5sup(m) as the photometry standards it has been found with high accuracy the distribution of the total corona brightness up to r approximately equal to 4.5 Rsub(S) and its K- and F-corona components for E and N directions. Neither color effect nor flattening is found in the dust component (r -6 Esub(S)

NmF2 and hmF2 measurements at 95° E and 127° E around the EIA northern crest during 2010-2014

Science.gov (United States)

Kalita, Bitap Raj; Bhuyan, Pradip Kumar; Yoshikawa, Akimasa

2015-11-01

The characteristics of the F2 layer parameters NmF2 and hmF2 over Dibrugarh (27.5° N, 95° E, 17° N geomagnetic, 43° dip) measured by a Canadian Advanced Digital Ionosonde (CADI) for the period of August 2010 to July 2014 are reported for the first time from this low mid-latitude station lying within the daytime peak of the longitudinal wave number 4 structure of equatorial anomaly (EIA) around the northern edge of anomaly crest. Equinoctial asymmetry is clearly observed at all solar activity levels whereas the midday winter anomaly is observed only during high solar activity years and disappears during the temporary dip in solar activity in 2013 but forenoon winter anomaly can be observed even at moderate solar activity. The NmF2/hmF2 variations over Dibrugarh are compared with that of Okinawa (26.5° N, 127° E, 17° N geomagnetic), and the eastward propagation speed of the wave number 4 longitudinal structure from 95° E to 127° E is estimated. The speed is found to be close to the theoretical speed of the wave number 4 (WN4) structure. The correlation of daily NmF2 over Dibrugarh and Okinawa with solar activity exhibits diurnal and seasonal variations. The highest correlation in daytime is observed during the forenoon hours in equinox. The correlation of daily NmF2 (linear or non-linear) with solar activity exhibits diurnal variation. A tendency for amplification with solar activity is observed in the forenoon and late evening period of March equinox and the postsunset period of December solstice. NmF2 saturation effect is observed only in the midday period of equinox. Non-linear variation of neutral composition at higher altitudes and variation of recombination rates with solar activity via temperature dependence may be related to the non-linear trend. The noon time maximum NmF2 over Dibrugarh exhibits better correlation with equatorial electrojet (EEJ) than with solar activity and, therefore, new low-latitude NmF2 index is proposed taking both solar

Satisfaction Data Collected by E-mail and Smartphone for Emergency Department Patients: How Do Responders Compare With Nonresponders?

Science.gov (United States)

Strickler, Jeffery C; Lopiano, Kenneth K

2016-11-01

This study profiles an innovative approach to capture patient satisfaction data from emergency department (ED) patients by implementing an electronic survey method. This study compares responders to nonresponders. Our hypothesis is that the cohort of survey respondents will be similar to nonresponders in terms of the key characteristics of age, gender, race, ethnicity, ED disposition, and payor status. This study is a cross-sectional design using secondary data from the database and provides an opportunity for univariate analysis of the key characteristics for each group. The data elements will be abstracted from the database and compared with the same key characteristics from a similar sample from the database on nonresponders to the ED satisfaction survey. Age showed a statistically significant difference between responders and nonresponders. Comparison by disposition status showed no substantial difference between responders and nonresponders. Gender distribution showed a greater number of female than male responders. Race distribution showed a greater number and response by white and Asian patients as compared with African Americans. A review of ethnicity showed fewer Hispanics responded. An evaluation by payor classification showed greater number and response rate by those with a commercial or Workers Comp payor source. The response rate by Medicare recipients was stronger than expected; however, the response rate by Medicaid recipients and self-pay could be a concern for underrepresentation by lower socioeconomic groups. Finally, the evaluation of the method of notification showed that notification by both e-mail and text substantially improved response rates. The evaluation of key characteristics showed no difference related to disposition, but differences related to age, gender, race, ethnicity, and payor classification. These results point to a potential concern for underrepresentation by lower socioeconomic groups. The results showed that notification by

77 FR 71643 - Standard Mail Pricing

Science.gov (United States)

2012-12-03

... POSTAL REGULATORY COMMISSION [Docket No. R2013-1; Order No.1556] Standard Mail Pricing AGENCY: Postal Regulatory Commission. ACTION: Notice. SUMMARY: The Commission is noticing a recent Postal Service filing concerning Standard Mail pricing and related matters. This notice informs the public of the filing...

L’émergence de l’âge adulte : de l’impact des référentiels institutionnels en France et au Québec 

Directory of Open Access Journals (Sweden)

Stéphane Moulin

2012-01-01

Full Text Available La théorie de l’âge adulte émergeant soutient que la période de 18 à 25 ans constitue un nouvel âge des parcours de vie qui n’est pas structurée par les institutions. Cet article vise à mettre cette affirmation à l’épreuve de la comparaison internationale à travers une analyse qualitative comparée de l’entrée des étudiants dans l’âge adulte au Québec et en France. Un contraste important est observé dans le processus d’émergence du sentiment d’être adulte : les étudiants se déclarent adultes dès le début du post-secondaire au Québec mais seulement à la fin de leurs études en France. Ce contraste est expliqué par des référentiels institutionnels nationaux qui structurent des conceptions différenciées de l’être adulte, du rôle des parents ainsi que du travail rémunéré.Emerging Adulthood: differential impacts of institutional referentials in France and QuébecThe theory of ‘Emerging Adulthood’ argues that the period between 18 and 25 years of age constitutes a new stage of the life-course that is unstructured by institutions. This article seeks to put this statement to the test of international comparison by a qualitative comparison of student entry to adulthood in France and Québec. A gap is observed between the two processes of emerging adulthood: Quebec students tend to identify themselves as adults at the very beginning of their postsecondary studies while French students declare themselves adults only after their postsecondary studies. We suggest that this gap is explained by national institutional referentials that shape differential conceptions of adulthood, role of parents and remunerative work.La accesión a la edad adulta. Impacto de los elementos de referencia institucionales en Francia y en Quebec (CanadaLa teoría de la “adultez emergente” afirma que el periodo comprendido entre los 18 y los 25 años no está estructurado por las instituciones. Este artículo intenta poner a

1172-IJBCS-Article-Kadidia Sanon

African Journals Online (AJOL)

DR GATSING

2 Laboratoire de Biologie et Physiologie Végétales, Université Antilles-Guyane, BP. 592, 97159 Pointe-à-. Pitre, Guadeloupe, France. E-mail : Amadou.Ba@ird.fr . 3 Laboratoire Commun de Microbiologie (UCAD-IRD-ISRA), BP 1386 Bel Air, Dakar, Sénégal. *Auteur correspondant, E-mail : sbkady@gmail.com; Tél : 226 50 ...

75 FR 39477 - New Standards for Domestic Mailing Services

Science.gov (United States)

2010-07-09

... markets, test new mailpieces, and increase the frequency of their mailings at reduced net postage prices... growth of automation letter-size mail, particularly pieces that are part of full-service Intelligent Mail[supreg] automation mailings entered at PostalOne![supreg] acceptance facilities. Accordingly, we propose...

Genetic Diversity of Blumeria graminis f. sp hordei in Central Europe and Its Comparison with Australian Population

Czech Academy of Sciences Publication Activity Database

Komínková, Eva; Dreiseitl, A.; Malečková, Eva; Doležel, Jaroslav; Valárik, Miroslav

2016-01-01

Roč. 11, č. 11 (2016), č. článku e0167099. E-ISSN 1932-6203 R&D Projects: GA MŠk(CZ) LO1204; GA MŠk(CZ) LD14105 Institutional support: RVO:61389030 Keywords : barley powdery mildew * f.sp hordei * isozyme variation * ssr markers * virulence * pathogen * complexity * france * frequencies * resistance Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.806, year: 2016

Periodic diffeomorphisms on homotopy E(4) surfaces

Indian Academy of Sciences (India)

College of Arts and Sciences, Shanghai Maritime University, Shanghai 201306, China. E-mail: lihongxia_2002@163.com. MS received 16 February 2013. Abstract. In this paper, we .... restriction of F0 onto Uλ ⊕ Vλ, we obtain a map. Fλ : Uλ ⊕ Vλ → Uλ ⊕ Vλ. Note that Fλ is a S1-equivariant map, where S1 acts on i trivially ...

PCDD/F and PCB multi-media ambient concentrations, congener patterns and occurrence in a Mediterranean coastal lagoon (Etang de Thau, France)

Energy Technology Data Exchange (ETDEWEB)

Castro-Jimenez, J. [European Commission-DG Joint Research Centre, Institute for Environment and Sustainability(IES), TP 290, Via Enrico Fermi, 1. 21020 Ispra (Vatican City State, Holy See,) (Italy)], E-mail: javier.castro-jimenez@jrc.it; Deviller, G.; Ghiani, M.; Loos, R.; Mariani, G.; Skejo, H.; Umlauf, G.; Wollgast, J. [European Commission-DG Joint Research Centre, Institute for Environment and Sustainability(IES), TP 290, Via Enrico Fermi, 1. 21020 Ispra (Vatican City State, Holy See,) (Italy); Laugier, T. [Ifremer, Laboratory of Environmental Resources, Bd Jean Monnet, BP 171, 34203 Sete Cedex (France); Heas-Moisan, K.; Leaute, F.; Munschy, C.; Tixier, C.; Tronczynski, J. [Ifremer, Laboratory of Biogeochemistry of Organic Contaminants, BP 21105, 44311 Nantes Cedex 3 (France)

2008-11-15

Ambient concentrations, congener patterns and multi-media distribution of PCDD/Fs and PCBs were determined in air, water, sediment and mussels in a semi-enclosed marine ecosystem (Thau lagoon, France). {sigma}2,3,7,8-PCDD/F and {sigma}7ICES PCB air concentrations (0.2-1.4 and 31-57 pg m{sup -3}, respectively) were typical of rural areas. Concentrations in the water column were very low for PCDD/Fs (163-476 fg L{sup -1}) and low for PCBs (138-708 pg L{sup -1}). PCDD/F and PCB concentrations found in surface sediment (0.15-1.6 and 2.5-33 ng g{sup -1} d.w., respectively) and mussel (13-21 pg g{sup -1} d.w. and 10-39 ng g{sup -1} d.w., respectively) were medium levels. PCDD/F congener patterns observed in air, water particulate phase and sediments were similar suggesting direct coupling among these compartments and atmospheric inputs of PCDD/Fs into the lagoon. Conversely, for the same set of samples, similar patterns were not observed for PCBs in the mentioned compartments. - Multi-media ambient concentrations and distribution of PCDD/Fs and PCBs in Thau Lagoon provide insight into the POPs behavior in semi-enclosed marine ecosystems.

Evaluation of a Tailored Direct-Mail Marketing Strategy for Recruiting the 19- to 23-Year-Old Market.

Science.gov (United States)

1983-05-01

17AD-A12.9 860 EVALUATION OF A TAILORED DIRECT-MAIL MARKETING STRATEGY 1/ FOR RECRUITNG TH.U) WESAT INC ROCKVILLE MD K FERNANDES ET AL MAY 83 NPRDC...STANDARDS-1963-A EVALUATION OF A TAILORED DIRECT-MAIL MARKETING STRATEGY FOR RECRUITING THE 19- TO 23-YEAR-OLD MARKET APPRVEDFORPUBLIC RELE AnE [B...EVALUATION OF A TAILORED DIRECT-MAIL MARKETING STRATEGY FOR RECRUITING THE 19- TO 23-YEAR-OLD MARKET Kathleen Fernandes Navy Personnel Research and

77 FR 70849 - International Mail Contract

Science.gov (United States)

2012-11-27

... POSTAL REGULATORY COMMISSION [Docket No. R2013-2; Order No.1550] International Mail Contract... Service filing concerning a Type 2 rate adjustment in conjunction with a mail contract with China Post... Equivalent Agreement, November 15, 2012 (Notice). Contract history and scope. The Agreement is a successor to...

France

International Nuclear Information System (INIS)

Hourcade, J.C.

1990-01-01

The French energy system, like that of most energy-importing nations, was profoundly transformed by the first oil shock. But France was more vulnerable than any other industrialized country besides Japan to oil supply disruption: in 1973, the nation imported 77 percent of total primary energy requirements of 7.6 EJ, and 98 percent of its petroleum. Two imperatives have since formed the 'French response' to the threat of external energy supply disruptions: augmentation of the rate of energy self-sufficiency, and minimization of major macroeconomic dislocations. These two objectives displaced a high priority in France in the early 1970s - protection of the natural environment. Because France has embraced nuclear power, it is often viewed by its European neighbors as having feeble ecological sensibility. At that time, France had a rather advanced policy in this field: sulfur emissions laws were enacted in 1967 and a Ministry of Environment was created in January 1971. Now that environmental concerns have re-emerged as an important force, France finds itself with a plausible greenhouse response in a mix of policies - without environmental protection having been the objective envisioned

Electronic Mail in Academic Settings: A Multipurpose Communications Tool.

Science.gov (United States)

D'Souza, Patricia Veasey

1992-01-01

Explores possible uses of electronic mail in three areas of the academic setting: instruction, research, and administration. Electronic mail is defined, the components needed to get started with electronic mail are discussed, and uses and benefits of electronic mail in diverse educational environments are suggested. (12 references) (DB)

14 CFR 1212.603 - Mailing lists.

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Mailing lists. 1212.603 Section 1212.603 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION PRIVACY ACT-NASA REGULATIONS Instructions for NASA Employees § 1212.603 Mailing lists. NASA will not sell, rent, or otherwise disclose an...

Smooth Mailing

Science.gov (United States)

Palmer, Tracey

2010-01-01

In fundraising today, a wealth of communications tools makes it increasingly easier to contact prospective donors--but is it getting harder to really connect with them? Do the new tools work as well as the old ones? In the second decade of online marketing, all the tools of the trade are subject to scrutiny. Direct mail has been a mainstay of the…

CDH1 regulates E2F1 degradation in response to differentiation signals in keratinocytes.

Science.gov (United States)

Singh, Randeep K; Dagnino, Lina

2017-01-17

The E2F1 transcription factor plays key roles in skin homeostasis. In the epidermis, E2F1 expression is essential for normal proliferation of undifferentiated keratinocytes, regeneration after injury and DNA repair following UV radiation-induced photodamage. Abnormal E2F1 expression promotes nonmelanoma skin carcinoma. In addition, E2F1 must be downregulated for proper keratinocyte differentiation, but the relevant mechanisms involved remain poorly understood. We show that differentiation signals induce a series of post-translational modifications in E2F1 that are jointly required for its downregulation. Analysis of the structural determinants that govern these processes revealed a central role for S403 and T433. In particular, substitution of these two amino acid residues with non-phosphorylatable alanine (E2F1 ST/A) interferes with E2F1 nuclear export, K11- and K48-linked polyubiquitylation and degradation in differentiated keratinocytes. In contrast, replacement of S403 and T433 with phosphomimetic aspartic acid to generate a pseudophosphorylated E2F1 mutant protein (E2F1 ST/D) generates a protein that is regulated in a manner indistinguishable from that of wild type E2F1. Cdh1 is an activating cofactor that interacts with the anaphase-promoting complex/cyclosome (APC/C) ubiquitin E3 ligase, promoting proteasomal degradation of various substrates. We found that Cdh1 associates with E2F1 in keratinocytes. Inhibition or RNAi-mediated silencing of Cdh1 prevents E2F1 degradation in response to differentiation signals. Our results reveal novel regulatory mechanisms that jointly modulate post-translational modifications and downregulation of E2F1, which are necessary for proper epidermal keratinocyte differentiation.

76 FR 27952 - Airworthiness Directives; Eurocopter France Model EC 120B Helicopters

Science.gov (United States)

2011-05-13

... aviation authority for France, has issued French AD No. F-2005-175, dated October 26, 2005, on behalf of... .Issued in Fort Worth, Texas, on April 27, 2011. Scott A. Horn, Acting Manager, Rotorcraft Directorate...

Mobilização política por e-mail: uma análise da Avaaz como ator-rede

Directory of Open Access Journals (Sweden)

Marcelo Castañeda

2015-04-01

Full Text Available The article analyzes the Avaaz (an organization that uses the internet intensively, their practices and operating flows in light of the actor-network theory developed by Bruno Latour. To do this, the paper begins by presenting this theoretical model that seeks to insert material objects in sociological analysis in order to characterize the organization of campaigns as a heterogeneous group composed of human and non-human that are configured to each campaign launched. The article focuses on the characterization of Avaaz members, their distribution around the world, e-mail alerts that are sent to members, the participation opportunities offered, the different themes and targets built each campaign.

Probióticos e prebióticos na prevenção e no tratamento de doenças em lactentes e crianças

OpenAIRE

Vandenplas,Yvan; Veereman-Wauters,Genevieve; Greef,Elisabeth De; Peeters,Stefaan; Casteels,Ann; Mahler,Tania; Devreker,Thierry; Hauser,Bruno

2011-01-01

OBJETIVO: Avaliar o impacto do uso de probióticos e prebióticos na saúde das crianças. FONTES DOS DADOS: Foram pesquisados os bancos de dados MEDLINE e LILACS, selecionando-se artigos relevantes em inglês e francês. SÍNTESE DOS DADOS: O leite humano é rico em oligossacarídeos prebióticos e pode conter probióticos. Não existem dados sugerindo que a adição de probióticos a fórmulas para lactentes possa ser prejudicial, mas as evidências de sua eficácia são insuficientes para que seja recomendad...

Les Arméniens communistes en France, une histoire oubliée

Directory of Open Access Journals (Sweden)

Astrig Atamian

2007-09-01

Full Text Available Si le nom de Manouchian, immortalisé par l’Affiche rouge, résonne bien au delà de la communauté arménienne, rares sont ceux parmi les Arméniens à connaître son parcours et celui de ses camarades dans la France de l’entre-deux-guerres. Dans un ouvrage récent sur les Arméniens de Vienne (dans l’Isère, Anahide Ter Minassian affirme que « dans le milieu ouvrier viennois […], les communistes arméniens ont été influents avant, pendant, et après la Seconde Guerre mondiale »1. Comment expliquer alors que parmi les travaux sur les Arméniens en France, aucun ne s’appesantit sur eux ? Il semblerait en effet que la communauté arménienne ait souvent été envisagée comme un tout homogène ne portant pas de dissensions politiques ou sociales. Les Arméniens eux-mêmes, soucieux de ne pas raviver les querelles d’hier, et cherchant à offrir un interlocuteur unique aux élus de la République, ont cédé au « mythe de l’unité ». Mais ne serait-on pas tenté de voir, dans cet oubli du rôle des communistes, le sort réservé au groupe des « vaincus », eux qui pendant des décennies s’étaient montrés hostiles à l’idée d’une Arménie indépendante ?Si bien el nombre de Manouchian, inmortalizado por «el Afiche Rojo», resuena bastante mas allá que en la sola comunidad de los armenios, son escasos en cambio los armenios que conocen su trayectoria así como la de sus camaradas en la Francia del periodo situado entre las dos guerras mundiales. En un texto reciente sobre los armenios de Viena (Isère-Francia, Anahide Ter Minassian afirma que «en los medios obreros de Viena […] los comunistas armenios fueron influyentes, antes, durante y después de la Segunda Guerra Mundial». Entonces, ¿cómo explicar que entre los trabajos sobre los armenios de Francia nadie lo mencione? La comunidad armenia parece haber sido considerada como un todo homogéneo en el que no hay lugar para disenciones políticas o

7 CFR 319.55-7 - Importations by mail.

Science.gov (United States)

2010-01-01

... foreign mailing point by a special mailing tag directing the package to a Plant Protection and Quarantine... 7 Agriculture 5 2010-01-01 2010-01-01 false Importations by mail. 319.55-7 Section 319.55-7 Agriculture Regulations of the Department of Agriculture (Continued) ANIMAL AND PLANT HEALTH INSPECTION...

The C.E.F.R.I

International Nuclear Information System (INIS)

Canipelle, A.D.

1999-01-01

The C.E.F.R.I. (French Committee of Enterprises certification for the training and Follow up of personnel working under Ionizing Radiations) has for aim to create a frame of mind, a culture of prevention and optimization in the field of radiation protection by the brought into operation in intervening enterprises and training organisms. (N.C.)

A regência dos verbos falar, sonhar, agradecer, pensar, colaborar e protestar do português e do francês sob a ótica da linguística contrastiva

OpenAIRE

Edson José Gomes

2004-01-01

A presente pesquisa contrasta a regência verbal do Português Língua Materna (PLM) e o ?complément d?object indirect (COI)? do Francês Língua Estrangeiro (FLE) a fim de identificar o tipo de transferência, negativa ou positiva, que a primeira exerce sob a segunda. Para tal, foram escolhidos os verbos ?falar?, ?sonhar?, ?agradecer?, ?pensar? ?colaborar? e ?protestar? (?parler?, ?rêver?, ?remercier?, ?penser?, ?collaborer? e ?protester?, respectivamente). A escolha dos verbos acima deveu-se por ...

A potential oncogenic role of the commonly observed E2F5 overexpression in hepatocellular carcinoma

Institute of Scientific and Technical Information of China (English)

Yuzhu Jiang; Seon-Hee Yim; Hai-Dong Xu; Seung-Hyun Jung; So Young Yang; Hae-Jin Hu; Chan-Kwon Jung; Yeun-Jun Chung

2011-01-01

AIM: To explore the expression pattern of E2F5 in primary hepatocellular carcinomas (HCCs) and elucidate the roles of E2F5 in hepatocarcinogenesis. METHODS: E2F5 expression was analyzed in 120 primary HCCs and 29 normal liver tissues by immunohistochemistry analysis. E2F5-small interfering RNA was transfected into HepG2, an E2F5-overexpressed HCC cell line. After E2F5 knockdown, cell growth capacity and migrating potential were examined. RESULTS: E2F5 was significantly overexpressed in primary HCCs compared with normal liver tissues (P = 0.008). The E2F5-silenced cells showed significantly reduced proliferation (P = 0.004). On the colony formation and soft agar assays, the number of colonies was significantly reduced in E2F5-silenced cells (P = 0.004 and P = 0.009, respectively). E2F5 knockdown resulted in the accumulation of G0/G1 phase cells and a reduction of S phase cells. The number of migrating/invading cells was also reduced after E2F5 knockdown (P = 0.021). CONCLUSION: To our knowledge, this is the first evidence that E2F5 is commonly overexpressed in primary HCC and that E2F5 knockdown significantly repressed the growth of HCC cells.

Knockdown of E2f1 by RNA interference impairs proliferation of rat cells in vitro

Directory of Open Access Journals (Sweden)

Luciana dos Reis Vasques

2010-01-01

Full Text Available E2F1 plays a key role in cell-cycle regulation in mammals, since its transcription factor activity controls genes required for DNA synthesis and apoptosis. E2F1 deregulation is a common feature among different tumor types and can be a major cause of cell proliferation. Thus, blocking E2F1 expression by RNA interference represents a promising therapeutic approach. In this study, the introduction of specific short hairpin RNAs (shRNAs reduced E2f1 expression by up to 77%, and impaired rat glioma cell proliferation by approximately 70%, as compared to control cells. Furthermore, we investigated the expression of E2f1 target genes, Cyclin A and Cyclin E. Cyclin A was found to be down-regulated, whereas Cyclin E had similar expression to control cells, indicating that gene(s other than E2f1 control its transcription. Other E2f family members, E2f2 and E2f3, which have been classified in the same subgroup of transcriptional activators, were also analyzed. Expression of both E2f2 and E2f3 was similar to control cells, showing no cross-inactivation or up-regulation to compensate for the absence of E2f1. Nevertheless, their expression was insufficient to maintain the initial proliferation potential. Taken together, our results suggest that shE2f1 is a promising therapy to control tumor cell proliferation.

The Role of the E2F Transcription Factor Family in UV-Induced Apoptosis

Directory of Open Access Journals (Sweden)

Orla Gannon

2011-12-01

Full Text Available The E2F transcription factor family is traditionally associated with cell cycle control. However, recent data has shown that activating E2Fs (E2F1-3a are potent activators of apoptosis. In contrast, the recently cloned inhibitory E2Fs (E2F7 and 8 appear to antagonize E2F-induced cell death. In this review we will discuss (i the potential role of E2Fs in UV-induced cell death and (ii the implications of this to the development of UV-induced cutaneous malignancies.

Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma

NARCIS (Netherlands)

Kent, Lindsey N.; Bae, Sooin; Tsai, Shih-Yin; Tang, Xing; Srivastava, Arunima; Koivisto, Christopher; Martin, Chelsea K.; Ridolfi, Elisa; Miller, Grace C.; Zorko, Sarah M.; Plevris, Emilia; Hadjiyannis, Yannis; Perez, Miguel; Nolan, Eric; Kladney, Raleigh; Westendorp, Bart; de Bruin, Alain; Fernandez, Soledad; Rosol, Thomas J.; Pohar, Kamal S.; Pipas, James M.; Leone, Gustavo

2017-01-01

Disruption of the retinoblastoma (RB) tumor suppressor pathway, either through genetic mutation of upstream regulatory components or mutation of RB1 itself, is believed to be a required event in cancer. However, genetic alterations in the RB-regulated E2F family of transcription factors are

What can EU policy do to support renewable electricity in France?

International Nuclear Information System (INIS)

Sartor, Oliver

2016-04-01

Under the 2030 Climate and Energy Package, the European Union has set itself a target of increasing the share of renewable energy from to 27%. Electricity will play a key role in achieving these goals, with the share of renewable power projected to increase to around 47% of the electricity mix by 2030. While electricity is only one part of the energy system, electricity is therefore a vital sub-sector of the EU's renewable energy strategy to 2030. As the second largest energy consumer in Europe, and with relatively ambitious national goals of achieving 32% renewable energy and 40% renewable electricity (RES-E) by 2030, France will be critical to achieving the EU's objectives. As the most interconnected electricity market in Europe, France's approach to renewable electricity will also influence the redesign of electricity markets to cope with higher shares of variable RES-E in its region. Facilitating the efficient deployment and integration of renewable electricity in France is therefore an important sub-chapter of European renewable energy policy going forward. The integration of higher shares of renewable electricity in France is a significant domestic policy challenge. But EU can take a number steps to facilitate the achievement of France's goals. One area where the EU has value added is by ensuring that EU rules for state aid to renewables do not inadvertently become a barrier to cost-efficient deployment of renewables in France. The EU should also push France (and all Member States) to develop a coherent and comprehensive RES-E market integration strategy for 2030 to facilitate national and regional market development. In addition, the EU should push France to improve the quality of its enabling environment for renewable electricity projects, so that it is in line with EU benchmarks

Targeting Synthetic Lethal Interactions between Myc and the eIF4F Complex Impedes Tumorigenesis

Directory of Open Access Journals (Sweden)

Chen-Ju Lin

2012-04-01

Full Text Available The energetically demanding process of translation is linked to multiple signaling events through mTOR-mediated regulation of eukaryotic initiation factor (eIF4F complex assembly. Disrupting mTOR constraints on eIF4F activity can be oncogenic and alter chemotherapy response, making eIF4F an attractive antineoplastic target. Here, we combine a newly developed inducible RNAi platform and pharmacological targeting of eIF4F activity to define a critical role for endogenous eIF4F in Myc-dependent tumor initiation. We find elevated Myc levels are associated with deregulated eIF4F activity in the prelymphomatous stage of the Eμ-Myc lymphoma model. Inhibition of eIF4F is synthetic lethal with elevated Myc in premalignant pre-B/B cells resulting in reduced numbers of cycling pre-B/B cells and delayed tumor onset. At the organismal level, eIF4F suppression affected a subset of normal regenerating cells, but this was well tolerated and rapidly and completely reversible. Therefore, eIF4F is a key Myc client that represents a tumor-specific vulnerability.

E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation

International Nuclear Information System (INIS)

Hao, Hongying; Dong, Yanbin; Bowling, Maria T; Gomez-Gutierrez, Jorge G; Zhou, H Sam; McMasters, Kelly M

2007-01-01

PUMA is a pro-apoptotic Bcl-2 family member that has been shown to be involved in apoptosis in many cell types. We sought to ascertain whether induction of PUMA plays a crucial role in E2F-1-induced apoptosis in melanoma cells. PUMA gene and protein expression levels were detected by real-time PCR and Western blot in SK-MEL-2 and HCT116 cell lines after Ad-E2F-1 infection. Activation of the PUMA promoter by E2F-1 overexpression was detected by dual luciferase reporter assay. E2F-1-induced Bax translocation was shown by immunocytochemistry. The induction of caspase-9 activity was measured by caspase-9 colorimetric assay kit. Up-regulation of the PUMA gene and protein by E2F-1 overexpression was detected by real-time PCR and Western blot analysis in the SK-MEL-2 melanoma cell line. In support of this finding, we found six putative E2F-1 binding sites within the PUMA promoter. Subsequent dual luciferase reporter assay showed that E2F-1 expression could increase the PUMA gene promoter activity 9.3 fold in SK-MEL-2 cells. The role of PUMA in E2F-1-induced apoptosis was further investigated in a PUMA knockout cell line. Cell viability assay showed that the HCT116 PUMA-/- cell line was more resistant to Ad-E2F-1-mediated cell death than the HCT116 PUMA+/+ cell line. Moreover, a 2.2-fold induction of the PUMA promoter was also noted in the HCT116 PUMA+/+ colon cancer cell line after Ad-E2F-1 infection. Overexpression of a truncated E2F-1 protein that lacks the transactivation domain failed to up-regulate PUMA promoter, suggesting that PUMA may be a transcriptional target of E2F-1. E2F-1-induced cancer cell apoptosis was accompanied by Bax translocation from the cytosol to mitochondria and the induction of caspase-9 activity, suggesting that E2F-1-induced apoptosis is mediated by PUMA through the cytochrome C/Apaf-1-dependent pathway. Our studies strongly demonstrated that E2F-1 induces melanoma cell apoptosis via PUMA up-regulation and Bax translocation. The signaling

Effective atomic numbers (Z_e_f_f) of based calcium phosphate biomaterials: a comparative study

International Nuclear Information System (INIS)

Fernandes Zenobio, Madelon Aparecida; Gonçalves Zenobio, Elton; Silva, Teógenes Augusto da; Socorro Nogueira, Maria do

2016-01-01

This study determined the interaction of radiation parameters of four biomaterials as attenuators to measure the transmitted X-rays spectra, the mass attenuation coefficient and the effective atomic number by spectrometric system comprising the CdTe detector. The biomaterial BioOss"® presented smaller mean energy than the other biomaterials. The μ/ρ and Z_e_f_f of the biomaterials showed their dependence on photon energy. The data obtained from analytical methods of x-ray spectra, µ/ρ and Z_e_f_f_, using biomaterials as attenuators, demonstrated that these materials could be used as substitutes for dentin, enamel and bone. Further, they are determinants for the characterization of the radiation in tissues or equivalent materials. - Highlights: • Measure of the transmitted x-rays spectra using based calcium phosphate biomaterials as attenuators. • Determination effective atomic number using four dental biomaterials. • Determination of the mass attenuation coefficient (µ/ρ) of the biomaterials samples calculated by the WinXCOM software. • Determination of the chemical composition of calcium phosphate biomaterials.

39 CFR 233.3 - Mail covers.

Science.gov (United States)

2010-07-01

.... For purpose of these regulations, the following terms are hereby defined. (1) Mail cover is the... criminal law. (3) When time is of the essence, the Chief Postal Inspector, or designee, may act upon an... furnish information as defined in § 233.3(c)(1) to any person, except as authorized by a mail cover order...

75 FR 76282 - Domestic Shipping Services Pricing and Mailing Standards Changes

Science.gov (United States)

2010-12-08

... United States Postal Service, Domestic Mail Manual (DMM[reg]), to reflect changes to prices and mailing standards for the following Shipping Services: Express Mail[reg], Priority Mail[reg], Parcel Select[reg... following changes to Mailing Standards of the United States Postal Service, Domestic Mail Manual (DMM...

E2F transcription factors and digestive system malignancies: how much do we know?

Science.gov (United States)

Xanthoulis, Athanasios; Tiniakos, Dina G

2013-06-07

E2F family of transcription factors regulates various cellular functions related to cell cycle and apoptosis. Its individual members have traditionally been classified into activators and repressors, based on in vitro studies. However their contribution in human cancer is more complicated and difficult to predict. We review current knowledge on the expression of E2Fs in digestive system malignancies and its clinical implications for patient prognosis and treatment. E2F1, the most extensively studied member and the only one with prognostic value, exhibits a tumor-suppressing activity in esophageal, gastric and colorectal adenocarcinoma, and in hepatocellular carcinoma (HCC), whereas in pancreatic ductal adenocarcinoma and esophageal squamous cell carcinoma may function as a tumor-promoter. In the latter malignancies, E2F1 immunohistochemical expression has been correlated with higher tumor grade and worse patient survival, whereas in esophageal, gastric and colorectal adenocarcinomas is a marker of increased patient survival. E2F2 has only been studied in colorectal cancer, where its role is not considered significant. E2F4's role in colorectal, gastric and hepatic carcinogenesis is tumor-promoting. E2F8 is strongly upregulated in human HCC, thus possibly contributing to hepatocarcinogenesis. Adenoviral transfer of E2F as gene therapy to sensitize pancreatic cancer cells for chemotherapeutic agents has been used in experimental studies. Other therapeutic strategies are yet to be developed, but it appears that targeted approaches using E2F-agonists or antagonists should take into account the tissue-dependent function of each E2F member. Further understanding of E2Fs' contribution in cellular functions in vivo would help clarify their role in carcinogenesis.

Efficacy of a single oral dose of a live bivalent E. coli vaccine against post-weaning diarrhea due to F4 and F18-positive enterotoxigenic E. coli.

Science.gov (United States)

Nadeau, É; Fairbrother, J M; Zentek, J; Bélanger, L; Tremblay, D; Tremblay, C-L; Röhe, I; Vahjen, W; Brunelle, M; Hellmann, K; Cvejić, D; Brunner, B; Schneider, C; Bauer, K; Wolf, R; Hidalgo, Á

2017-08-01

F4- and F18-positive enterotoxigenic E. coli strains (F4-ETEC and F18-ETEC) are important causes of post-weaning diarrhea (PWD) in pigs. F4 (antigenic variant ac) and F18 (ab and ac) fimbriae are major antigens that play an important role in the early stages of infection. Herein, the efficacy of a live oral vaccine consisting of two non-pathogenic E. coli strains, one F4ac- and one F18ac-positive, was evaluated using F4ac-ETEC and F18ab-ETEC challenge models. A randomized, masked, placebo-controlled, block design, parallel-group confirmatory study with two different vaccination-challenge intervals (7 and 21 days) was conducted for each challenge model. The vaccine was administered in one dose, to ≥18-day-old piglets via drinking water. Efficacy was assessed by evaluating diarrhea, clinical observations, weight gain and fecal shedding of F4-ETEC or F18-ETEC. Anti-F4 and anti-F18 immunoglobulins in blood were measured. The vaccination resulted in significant reductions in clinical PWD and fecal shedding of F4-ETEC and F18-ETEC after the 7- and 21-day-post-vaccination heterologous challenges, except for after the 21-day-post-vaccination F4-ETEC challenge, when the clinical PWD was too mild to demonstrate efficacy. A significant reduction of mortality and weight loss by vaccination were observed following the F18-ETEC challenge. The 7-day protection was associated with induction of anti-F4 and anti-F18 IgM, whereas the 21-day protection was mainly associated with anti-F4 and anti-F18 IgA. The 7-day onset and 21-day duration of protection induced by this vaccine administered once in drinking water to pigs of at least 18days of age were confirmed by protection against F4-ETEC and F18-ETEC, and induction of F4 and F18-specific immunity. Cross protection of the vaccine against F18ab-E. coli was demonstrated for both the 7- and 21-day F18-ETEC challenges. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

Distinct mechanisms of nuclear accumulation regulate the functional consequence of E2F transcription factors

NARCIS (Netherlands)

Allen, K.E.; Luna, S. de la; Kerkhoven, R.M.; Bernards, R.A.; Thangue, N.B. La

1997-01-01

Transcription factor E2F plays an important role in coordinating and integrating early cell cycle progression with the transcription apparatus. It is known that physiological E2F arises when a member of two families of proteins, E2F and DP, interact as E2F/DP heterodimers and that transcriptional

Põhiseadus ja Eesti rahvuslikud huvid vs. Euroopa föderalism / Jüri Raidla

Index Scriptorium Estoniae

Raidla, Jüri, 1957-

2013-01-01

Eesti rahvuslikest huvidest, mis ei ole Euroopa Liidu föderaliseerumisega vastuolus, pigem vastupidi. Artikkel põhineb autori ja vabariigi presidendi vahel toimunud debatil 9. mail 2013 ning Juridica lugejakonverentsil peetud ettekandel 30. mail 2013 Tartus

The effects of mailing design characteristics on direct mail campaign performance

NARCIS (Netherlands)

Feld, S.; Frenzen, H.; Krafft, Manfred; Peters, K.; Verhoef, P.C.

Designing effective direct mail pieces is considered a key success factor in direct marketing. However, related published empirical research is scarce while design recommendations are manifold and often conflicting. Compared with prior work, our study aims to provide more elaborate and empirically

Modulation of the E2F1-driven cancer cell fate by the DNA damage response machinery and potential novel E2F1 targets in osteosarcomas

DEFF Research Database (Denmark)

Liontos, Michalis; Niforou, Katerina; Velimezi, Georgia

2009-01-01

Osteosarcoma is the most common primary bone cancer. Mutations of the RB gene represent the most frequent molecular defect in this malignancy. A major consequence of this alteration is that the activity of the key cell cycle regulator E2F1 is unleashed from the inhibitory effects of pRb. Studies...... in a clinical setting of human primary osteosarcomas and in E2F1-inducible osteosarcoma cell line models that are wild-type and deficient for p53. Collectively, our data demonstrated that high E2F1 levels exerted a growth-suppressing effect that relied on the integrity of the DNA damage response network...

Detection of the F meson production in the e+e--annihilation at a c.m. energy at 4.4 GeV

International Nuclear Information System (INIS)

Brandelik, R.

1981-01-01

The aim of this thesis had been to detect the F mesons via their decay into eta mesons. For this the eta rate between 4 and 5 GeV c.m. energy had been determined via the decay of the eta mesons into two photons. Energy and direction of the decay photons had been measured in the interior detector of DASP. As result of the analysis three c.m. energy intervals resulted with eta rates different from zero. An exceptionally evident eta signal of sigmasub(eta) = (5.15 +- 1.65)nb+-40% syst. error was measured for c.m. energies around 4.42 GeV and yielded thereby a first evidence for the F production. The detection of the F production resulted finally also in this energy interval from the measurement of the exclusive decay Fsup(+-)->πsup(+-)eta. From the additional detection of a correlation between produced eta mesons and low energy photons γsub(L) (Eγ + e - ->F + Fsup(-*) respectively e + e - ->Fsup(+*)Fsup(-*) was concluded. Thereby finally via a kinematic fit the detection of 6 events succeeded over a background of 0.2 events from e + e - ->F + Fsup(-*) respectively e + e - ->Fsup(+*)Fsup(-*) and Fsup(*)->γsub(L)F, Fsup(+-)->πsup(+-)eta,eta->2γ. Thereby the mass of F and Fsup(*) was determined to msub(F) = (2.04 +- 0.06)GeV and msub(F*) = (2.15 +- 0.06)MeV. The cross section for the 6 signal events was estimated to sigma(e + e - ->F + Fsup(-*))xB.R. (Fsup(+-)->πsup(+-)eta) = (0.41 +- 0.18)nb +-40% syst. error. (orig./HSI) [de

Manda quem pode e obedece quem tem juízo? Uma reflexão antropológica sobre disputas e conflitos nos espaços públicos brasileiro e francês

Directory of Open Access Journals (Sweden)

Fabio Reis Mota

2009-04-01

Full Text Available O objetivo deste texto é contribuir para uma compreensão antropológica acerca do significado da categoria confl ito nos espaços públicos brasileiro e francês, buscando ressaltar de que modo os regimes de ação dos atores são acionados de acordo com as gramáticas ou sensibilidades jurídicas que informam as suas tomadas de posição, focalizando a maneira como as disputas são conduzidas pelos atores em interação. Toma-se como ponto de partida duas situações vivenciadas no Brasil e na França, com o propósito de contrastá-las. The aim of this paper is to contribute to an anthropological understanding regarding the meaning of conflict in Brazilian and French public domains, underlining the way in which the regimes of action adopted by the actors involved are driven by the legal grammars or sensibilities which determine their stances, focusing on the way such disputes are carried out by the interacting actors. Two situations in Brazil and France are taken as the starting point and duly contrasted.

Differential expression of members of the E2F family of transcription factors in rodent testes

Directory of Open Access Journals (Sweden)

Toppari Jorma

2006-12-01

Full Text Available Abstract Background The E2F family of transcription factors is required for the activation or repression of differentially expressed gene programs during the cell cycle in normal and abnormal development of tissues. We previously determined that members of the retinoblastoma protein family that interacts with the E2F family are differentially expressed and localized in almost all the different cell types and tissues of the testis and in response to known endocrine disruptors. In this study, the cell-specific and stage-specific expression of members of the E2F proteins has been elucidated. Methods We used immunohistochemical (IHC analysis of tissue sections and Western blot analysis of proteins, from whole testis and microdissected stages of seminiferous tubules to study the differential expression of the E2F proteins. Results For most of the five E2F family members studied, the localizations appear conserved in the two most commonly studied rodent models, mice and rats, with some notable differences. Comparisons between wild type and E2F-1 knockout mice revealed that the level of E2F-1 protein is stage-specific and most abundant in leptotene to early pachytene spermatocytes of stages IX to XI of mouse while strong staining of E2F-1 in some cells close to the basal lamina of rat tubules suggest that it may also be expressed in undifferentiated spermatogonia. The age-dependent development of a Sertoli-cell-only phenotype in seminiferous tubules of E2F-1 knockout males corroborates this, and indicates that E2F-1 is required for spermatogonial stem cell renewal. Interestingly, E2F-3 appears in both terminally differentiated Sertoli cells, as well as spermatogonial cells in the differentiative pathway, while the remaining member of the activating E2Fs, E2F-2 is most concentrated in spermatocytes of mid to late prophase of meiosis. Comparisons between wildtype and E2F-4 knockout mice demonstrated that the level of E2F-4 protein displays a distinct

Disruption of Mouse Cytochrome P450 4f14 (Cyp4f14 Gene) Causes Severe Perturbations in Vitamin E Metabolism*

Science.gov (United States)

Bardowell, Sabrina A.; Duan, Faping; Manor, Danny; Swanson, Joy E.; Parker, Robert S.

2012-01-01

Vitamin E is a family of naturally occurring and structurally related lipophilic antioxidants, one of which, α-tocopherol (α-TOH), selectively accumulates in vertebrate tissues. The ω-hydroxylase cytochrome P450–4F2 (CYP4F2) is the only human enzyme shown to metabolize vitamin E. Using cDNA cloning, cell culture expression, and activity assays, we identified Cyp4f14 as a functional murine ortholog of CYP4F2. We then investigated the effect of Cyp4f14 deletion on vitamin E metabolism and status in vivo. Cyp4f14-null mice exhibited substrate-specific reductions in liver microsomal vitamin E-ω-hydroxylase activity ranging from 93% (γ-TOH) to 48% (γ-tocotrienol). In vivo data obtained from metabolic cage studies showed whole-body reductions in metabolism of γ-TOH of 90% and of 68% for δ- and α-TOH. This metabolic deficit in Cyp4f14−/− mice was partially offset by increased fecal excretion of nonmetabolized tocopherols and of novel ω-1- and ω-2-hydroxytocopherols. 12′-OH-γ-TOH represented 41% of whole-body production of γ-TOH metabolites in Cyp4f14−/− mice fed a soybean oil diet. Despite these counterbalancing mechanisms, Cyp4f14-null mice fed this diet for 6 weeks hyper-accumulated γ-TOH (2-fold increase over wild-type littermates) in all tissues and appeared normal. We conclude that CYP4F14 is the major but not the only vitamin E-ω-hydroxylase in mice. Its disruption significantly impairs whole-body vitamin E metabolism and alters the widely conserved phenotype of preferential tissue deposition of α-TOH. This model animal and its derivatives will be valuable in determining the biological actions of specific tocopherols and tocotrienols in vivo. PMID:22665481

Nível de atividade física, comorbidades e idade de pacientes hipertensos

Directory of Open Access Journals (Sweden)

Denise Rodrigues Bueno

2013-09-01

Full Text Available No envelhecimento, hábito inativo está associado a doenças crônicas. Existem diferentes domínios da atividade física, tais como: tempo livre e locomoção. O objetivo foi analisar associações entre diferentes domínios de atividade física, comorbidades e idade em hipertensos. Foram entrevistados 192 hipertensos. Classificados em menos ativos e mais ativos para atividades no lazer, locomoção, ocupação e total e estratificados em grupos etários. A circunferência de cintura foi avaliada e comorbidades auto referidas. O teste Qui-quadrado analisou as associações e o teste ANOVA one way comparou os grupos etários, adotando significância estatística quando p<0,05. As médias de atividade física ocupacional e total foram menores para idade igual ou acima dos 60 e 70 anos, respectivamente. A atividade ocupacional esteve associada à idade em mulheres e, ao colesterol e diabetes em homens, que também tiveram atividade física de locomoção associada à circunferência de cintura. Em síntese a atividade física de hipertensos associa-se a comorbidades para diferentes grupos etários e sexos.

E2F1-mediated human POMC expression in ectopic Cushing's syndrome.

Science.gov (United States)

Araki, Takako; Liu, Ning-Ai; Tone, Yukiko; Cuevas-Ramos, Daniel; Heltsley, Roy; Tone, Masahide; Melmed, Shlomo

2016-11-01

Cushing's syndrome is caused by excessive adrenocorticotropic hormone (ACTH) secretion derived from pituitary corticotroph tumors (Cushing disease) or from non-pituitary tumors (ectopic Cushing's syndrome). Hypercortisolemic features of ectopic Cushing's syndrome are severe, and no definitive treatment for paraneoplastic ACTH excess is available. We aimed to identify subcellular therapeutic targets by elucidating transcriptional regulation of the human ACTH precursor POMC (proopiomelanocortin) and ACTH production in non-pituitary tumor cells and in cell lines derived from patients with ectopic Cushing's syndrome. We show that ectopic hPOMC transcription proceeds independently of pituitary-specific Tpit/Pitx1 and demonstrate a novel E2F1-mediated transcriptional mechanism regulating hPOMC We identify an E2F1 cluster binding to the proximal hPOMC promoter region (-42 to +68), with DNA-binding activity determined by the phosphorylation at Ser-337. hPOMC mRNA expression in cancer cells was upregulated (up to 40-fold) by the co-expression of E2F1 and its heterodimer partner DP1. Direct and indirect inhibitors of E2F1 activity suppressed hPOMC gene expression and ACTH by modifying E2F1 DNA-binding activity in ectopic Cushing's cell lines and primary tumor cells, and also suppressed paraneoplastic ACTH and cortisol levels in xenografted mice. E2F1-mediated hPOMC transcription is a potential target for suppressing ACTH production in ectopic Cushing's syndrome. © 2016 Society for Endocrinology.

Optimization of territory control of the mail carrier by using Hungarian methods

Science.gov (United States)

Supian, S.; Wahyuni, S.; Nahar, J.; Subiyanto

2018-03-01

In this paper, the territory control of the mail carrier from the central post office Bandung in delivering the package to the destination location was optimized by using Hungarian method. Sensitivity analysis against data changes that may occur was also conducted. The sampled data in this study are the territory control of 10 mail carriers who will be assigned to deliver mail package to 10 post office delivery centers in Bandung. The result of this research is the combination of territory control optimal from 10 mail carriers as follows: mail carrier 1 to Cikutra, mail carrier 2 to Ujung Berung, mail carrier 3 to Dayeuh Kolot, mail carrier 4 to Padalarang, mail carrier 5 to Situ Saeur, mail carrier 6 to Cipedes, mail carrier 7 to Cimahi, mail carrier 8 to Soreang, mail carrier 9 to Asia-Afrika, mail carrier 10 to Cikeruh. Based on this result, manager of the central post office Bandung can make optimal decisions to assign tasks to their mail carriers.

Community pharmacy and mail order cost and utilization for 90-day maintenance medication prescriptions.

Science.gov (United States)

Khandelwal, Nikhil; Duncan, Ian; Rubinstein, Elan; Ahmed, Tamim; Pegus, Cheryl

2012-04-01

Pharmacy benefit management (PBM) companies promote mail order programs that typically dispense 90-day quantities of maintenance medications, marketing this feature as a key cost containment strategy to address plan sponsors' rising prescription drug expenditures. In recent years, community pharmacies have introduced 90-day programs that provide similar cost advantages, while allowing these prescriptions to be dispensed at the same pharmacies that patients frequent for 30-day quantities. To compare utilization rates and corresponding costs associated with obtaining 90-day prescriptions at community and mail order pharmacies for payers that offer equivalent benefits in different 90-day dispensing channels. We performed a retrospective, cross-sectional investigation using pharmacy claims and eligibility data from employer group clients of a large PBM between January 2008 and September 2010. We excluded the following client types: government, third-party administrators, schools, hospitals, 340B (federal drug pricing), employers in Puerto Rico, and miscellaneous clients for which the PBM provided billing services (e.g., the pharmacy's loyalty card program members). All employer groups in the sample offered 90-day community pharmacy and mail order dispensing and received benefits management services, such as formulary management and mail order pharmacy, from the PBM. We further limited the sample to employer groups that offered equivalent benefits for community pharmacy and mail order, defined as groups in which the mean and median copayments per claim for community and mail order pharmacy, by tier, differed by no more than 5%. Enrollees in the sample were required to have a minimum of 6 months of eligibility in each calendar year but were not required to have filled a prescription in any year. We evaluated pharmacy costs and utilization for a market basket of 14 frequently dispensed therapeutic classes of maintenance medications. The proportional share of claims for

Research helps EdF improve operating practices and control rooms [at nuclear power plants in France

International Nuclear Information System (INIS)

Leckner, J.-M.

1989-01-01

In September 1982, EdF set up a team to analyse incidents occurring in nuclear plants in France and elsewhere. This team consists of two groups of analysts: one for studying technical factors and one for investigating human factors. Medium-term objectives for the team involve work on the principal causes of malfunction and the extent to which significant incidents recur. Experience feedback, training and multifactor events, are the group's prime concerns. Information is gathered from two sources: simulators provide an analysis of operator behaviour in incident and accident situations; and plants themselves provide in-service data. The malfunctions which are examined are significant incidents listed according to ten criteria, the main ones being scrams, safety injection, events relating to technical specifications, malicious acts, discharge of radioactive substances and exposure of staff to ionizing radiation. Every week, all incidents are examined and communicated to the relevant analysts. The analyst must then draw up a summary, to include: a description of the facts; an analysis of the causes; and ideas for preventive actions. Many of the recommendations have now been carried out, with the result that recent years have seen a decline in human errors at French plants. (author)

Cranberry extract inhibits in vitro adhesion of F4 and F18+Escherichia coli to pig intestinal epithelium and reduces in vivo excretion of pigs orally challenged with F18+ verotoxigenic E. coli.

Science.gov (United States)

Coddens, Annelies; Loos, Michaela; Vanrompay, Daisy; Remon, Jean Paul; Cox, Eric

2017-04-01

F4 + E. coli and F18 + E. coli infections are an important threat for pig industry worldwide. Antibiotics are commonly used to treat infected piglets, but the emerging development of resistance against antibiotics raises major concerns. Hence, alternative therapies to prevent pigs from F4 + E. coli and F18 + E. coli infections need to be developed. Since cranberry previously showed anti-adhesive activity against uropathogenic E. coli, we aimed to investigate whether cranberry extract could also inhibit binding of F4 + E. coli and F18 + E. coli to pig intestinal epithelium. Using the in vitro villus adhesion assay, we found that low concentrations of cranberry extract (20μg or 100μg/ml) have strong inhibitory activity on F4 + E. coli (75.3%, S.D.=9.31 or 95.8%, S.D.=2.56, respectively) and F18 + E. coli adherence (100% inhibition). This effect was not due to antimicrobial activity. Moreover, cranberry extract (10mg or 100mg) could also abolish in vivo binding of F4 and F18 fimbriae to the pig intestinal epithelium in ligated loop experiments. Finally, two challenge experiments with F18 + E. coli were performed to address the efficacy of in-feed or water supplemented cranberry extract. No effect could be observed in piglets that received cranberry extract only in feed (1g/kg or 10g/kg). However, supplementation of feed (10g/kg) and drinking water (1g/L) significantly decreased excretion and diarrhea. The decreased infection resulted in a decreased serum antibody response indicating reduced exposure to F18 + E. coli. Copyright © 2017 Elsevier B.V. All rights reserved.

An additional DNS feature for different routing of electronic mail inside and outside of a campus network

International Nuclear Information System (INIS)

Bobyshev, A.; Ernst, M.

2001-01-01

Several years ago DESY faced the need to change the Electronic Mail Service to support it on a central cluster of servers. The centralized architecture was necessary for deployment of unified internal E-Mail standards, better quality of service and security. To implement a new policy for Electronic Mail Service and avoid huge modifications to a few hundreds network nodes, an additional DNS feature has been added to ISC's (Internet Software Consortium) software bind-4.9.7. The DNS servers running at DESY are capable of distinguishing between DNS queries coming from inside and outside of the campus network and reply with different list of MX (Mail Exchanger) records. The external hosts always get a list of MX records pointing to the central mail servers while the internal hosts may use different paths for mail exchange within the campus network. A modified version of DNS software has been used at DESY since 1997. It is fully compliant with the original goal of the project and shows good operational performance and reliability

Thermal analysis and phase diagrams of the LiF BiF{sub 3} e NaF BiF{sub 3} systems; Analise termica e diagramas de fase dos sistemas LiF-BiF{sub 3} e NaF-BiF{sub 3}

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Gerson Hiroshi de Godoy

2013-07-01

Investigations of the binary systems LiF-BiF{sub 3} and NaF-BiF{sub 3} were performed with the objective of clarifying the thermal behavior and phase equilibria of these systems and their intermediary phases, an important requisite for high-quality crystal growth. Several samples in the entire range of compositions (0 to 100 mol% BiF{sub 3}) of both systems were subjected to experiments of differential thermal analysis (DTA) and thermogravimetry (TG), and also of differential scanning calorimetry (DSC). A few specific compositions were selected for X-ray diffraction to supplement the experimental data. Due to the high vulnerability of BiF{sub 3} to oxygen contamination, its volatility and propensity to destroy metal parts upon heating, it was necessary to determine the optimal conditions for thermal analysis before investigating the systems themselves. Phase relations in the system LiF-BiF{sub 3} were completely clarified and a phase diagram was calculated and evaluated via the commercial software Factsage. The diagram itself consists in a simple peritectic system in which the only intermediary compound, LiBiF{sub 4}, decomposes into LiF and a liquid phase. The NaF-BiF{sub 3} system could not be completely elucidated and the phase relations in the NaF poor side (> 50% BiF{sub 3}) are still unknown. In the NaF rich side, however, the possible peritectoid decomposition of the compound NaBiF{sub 4} was identified. In both systems X-ray diffraction yielded crystal structures discrepant with the literature for the intermediary phases, LiBiF{sub 4}, NaBiF{sub 4} and a solid solution of NaF and BiF{sub 3} called {sup I.} The observed structures remain unknown and explanations for the discrepancies were proposed. (author)

Promoting walking among office employees ― evaluation of a randomized controlled intervention with pedometers and e-mail messages

Directory of Open Access Journals (Sweden)

Aittasalo Minna

2012-06-01

Full Text Available Abstract Background The purpose of the study was to evaluate a 6-month intervention to promote office-employees’ walking with pedometers and e-mail messages. Methods Participants were recruited by 10 occupational health care units (OHC from 20 worksites with 2,230 employees. Voluntary and insufficiently physically active employees (N = 241 were randomized to a pedometer (STEP, N = 123 and a comparison group (COMP, N = 118. STEP included one group meeting, log-monitored pedometer-use and six e-mail messages from OHC. COMP participated in data collection. Reach, effectiveness, adoption, implementation, maintenance (RE-AIM and costs were assessed with questionnaires (0, 2, 6, 12 months, process evaluation and interviews (12 months. Results The intervention reached 29% (N = 646 of employees in terms of participation willingness. Logistic regression showed that the proportion of walkers tended to increase more in STEP than in COMP at 2 months in “walking for transportation” (Odds ratio 2.12, 95%CI 0.94 to 4.81 and at 6 months in “walking for leisure” (1.86, 95%CI 0.94 to 3.69. Linear model revealed a modest increase in the mean duration of “walking stairs” at 2 and 6 months (Geometric mean ratio 1.26, 95%CI 0.98 to 1.61; 1.27, 0.98 to 1.64. Adoption and implementation succeeded as intended. At 12 months, some traces of the intervention were sustained in 15 worksites, and a slightly higher number of walkers in STEP in comparison with COMP was observed in “walking stairs” (OR 2.24, 95%CI 0.94 to 5.31 and in “walking for leisure” (2.07, 95%CI 0.99 to 4.34. The direct costs of the intervention were 43 Euros per participant. Conclusions The findings indicate only modest impact on some indicators of walking. Future studies should invest in reaching the employees, minimizing attrition rate and using objective walking assessment. Trial registeration ISRCTN79432107

39 CFR 20.3 - Availability of the International Mail Manual.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Availability of the International Mail Manual. 20.3 Section 20.3 Postal Service UNITED STATES POSTAL SERVICE INTERNATIONAL MAIL INTERNATIONAL POSTAL SERVICE § 20.3 Availability of the International Mail Manual. Copies of the International Mail Manual may...

Interconnection France-England; Interconnexion France-Angleterre

Energy Technology Data Exchange (ETDEWEB)

NONE

2001-07-01

These documents defines the interconnection France-England rules for the 2000 MW DC submarine cable directly linking the transmission networks of England and Wales and France. Rights to use Interconnector capacity from 1 April 2001 are to be offered through competitive tenders and auctions, full details of which are set out in the Rules. The contract and a guide to the application form are provided. (A.L.B.)

39 CFR 20.4 - Amendments to the International Mail Manual.

Science.gov (United States)

2010-07-01

... 39 Postal Service 1 2010-07-01 2010-07-01 false Amendments to the International Mail Manual. 20.4 Section 20.4 Postal Service UNITED STATES POSTAL SERVICE INTERNATIONAL MAIL INTERNATIONAL POSTAL SERVICE § 20.4 Amendments to the International Mail Manual. New issues of the International Mail Manual will be...

Immigration et affirmation : le cas des Africains en France

Directory of Open Access Journals (Sweden)

Claude Zesseu

2011-04-01

Full Text Available Cet article est un tour d’horizon des questions reliées à l’immigration et à l’intégration des Africains en France, de la période coloniale à nos jours. Il retrace les dates marquantes et les réseaux du flux migratoire Afrique-France et présente une synthèse ciblée des politiques d’immigration françaises. Il engage une réflexion sur les facteurs susceptibles d’entraver ou de favoriser l’intégration et l’affirmation socio-économique et politique des immigrants africains en France.

Utilization of radioisotopes in France, present and future

International Nuclear Information System (INIS)

Gauvenet, A.J.

1976-01-01

France is one of the countries having used radioisotopes very early. The first research reactor went critical in 1948, and has been used right from the start mainly to produce the radioisotopes for research and medicine. The growth in production was extremely fast, and the net receipts (excluding tax) amounted to F.52.3 million during 1974, of which F.20.9 million from export. The increase as compared with 1973 is 33%. The research and production facilities, which are concerned with medical applications, are in full expansion, Finally, the increasing use of trans-uranic elements, particularly of Pu-238 pacemakers, is noted. The uses of Cm-244 and Cf-252 are also growing. The problem at user level that undoubtedly requires the greatest attention is the regulations. The regulations on radioelements in France are reviewed in details on the following matters; poisonous substances, radioactive transport, waste, license for using artificial radioactive substances, etc. As the conclusion, the extremely ripid growth in the use of radioisotopes - mainly artificial ones - brought about the problems of adaptation with respect to the control and training regulations. One of the problems is obviously due to the fact that the personnel using such substances does not possess the specialization, training and managerial staff which marks the nuclear industry proper. It is therefore of prime significance to give unfailing attention to this use which is becoming the matter of major importance in France. The stress now placed on everything that concerns radiation has the great interest of forcing renewed awareness, thereby avoiding the degradation that the routine might bring. (Kobatake, H.)

A comparison of nonresponse in mail, telephone, and face-to-face surveys

NARCIS (Netherlands)

Hox, J.J.; Leeuw, E.D. de

1994-01-01

This article reports a meta-analysis of 45 studies that explicitly compare the response obtained using a mail, telephone or face-to-face survey. The data analysis uses a generalized hierarchical linear model. Sampling procedure (e.g., local convenience sample, random general sample), saliency of

Don't LOL at virtual visits. Technology is allowing more doctors and patients to consult via e-mail, and insurance companies are reimbursing for it.

Science.gov (United States)

Robeznieks, Andis

2007-10-15

In today's "I-gotta-know-now" society, many patients turn to e-mail to contact doctors on matters, as opposed to waiting for an in-person office visit. Now, some insurers are actually reimbursing doctors for their electronic time, which is also known as a "virtual visit." Internist Paul Tang, left, doesn't consider the practice mainstream yet. "No one is reimbursing us," he says.

75 FR 29893 - Business Reply Mail Online Application Option

Science.gov (United States)

2010-05-28

... POSTAL SERVICE 39 CFR Part 111 Business Reply Mail Online Application Option AGENCY: Postal Service TM . ACTION: Final rule. SUMMARY: The Postal Service TM will revise the Mailing Standards of the... option to obtain a Business Reply Mail[supreg] (BRM) permit online. Additionally, the electronic version...

Building mail server on distributed computing system

International Nuclear Information System (INIS)

Akihiro Shibata; Osamu Hamada; Tomoko Oshikubo; Takashi Sasaki

2001-01-01

The electronic mail has become the indispensable function in daily job, and the server stability and performance are required. Using DCE and DFS we have built the distributed electronic mail sever, that is, servers such as SMTP, IMAP are distributed symmetrically, and provides the seamless access

Tiger Rag na interpretação do Le Quintette du Hot Club de France: história, análise e práticas de performance Tiger Rag as performed by the Quintet of the Hot Club of France: history, analysis and performance practices

Directory of Open Access Journals (Sweden)

Adriana Costa

2011-06-01

Full Text Available Estudo sobre a assimilação do jazz na cultura popular francesa dos anos de 1930 e criação de uma sociedade de entusiastas desse estilo, especialmente em torno do Le Quintette du Hot Club de France. A transcrição e análise de Tiger Rag, música dos membros da Original Dixieland Jazz Band (Nick La Rocca, Eddie Edwards, Tony Sbarbaro, Larry Shields e Harry da Costa na interpretação do Le Quintette (LE QUINTETTE DU HOT CLUB DE FRANCE, 1934, remasterizado em 1993 revela suas práticas de performance, especialmente de seus solistas: Django Reinhardt, no violão, e Stephane Grappelli, no violino.Study about the assimilation of jazz into French popular culture of the 1930s and the emergence of a society of jazz enthusiasts, especially around Le Quintette du Hot Club de France. The transcription and analysis of Tiger Rag, composed by the members of the Original Dixieland Jazz Band (Nick La Rocca, Eddie Edwards, Tony Sbarbaro, Larry Shields and Harry da Costa and performed by Le Quintette reveal performance practices of its main soloists: Django Reinhardt on the guitar and Stephane Grappelli on the violin.

Management of outpatients in France with stable coronary artery disease. Findings from the prospeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease (CLARIFY) registry.

Science.gov (United States)

Danchin, Nicolas; Ferrieres, Jean; Guenoun, Maxime; Cattan, Simon; Rushton-Smith, Sophie K; Greenlaw, Nicola; Ferrari, Roberto; Steg, Philippe Gabriel

2014-01-01

Improvements in the treatment of coronary artery disease mean that an increasing number of patients survive acute cardiovascular events and live as outpatients with or without anginal symptoms. To determine the characteristics and management of contemporary outpatients with stable coronary artery disease in Western Europe, and to compare France with the other Western European countries. CLARIFY (prospeCtive observational LongitudinAl RegIstry oF patients with stable coronary arterY disease) is an international, prospective, observational, longitudinal study. Between November 2009 and July 2010, 32,954 adult outpatients with stable coronary artery disease (defined as a history of documented myocardial infarction [of >3 months], prior coronary revascularization, chest pain with myocardial ischaemia, or coronary stenosis of>50% proven by angiography) were enrolled in 45 countries. The demographics and management of CLARIFY patients enrolled in France were compared with those enrolled in other Western European countries (Austria, Belgium, Denmark, Germany, Greece, Ireland, Italy, Netherlands, Portugal, Spain, Switzerland and the UK). Of the 14,726 patients enrolled in Western Europe (mean age 66.2 [10.2] years; 79.6% male), 2432 (16.5%) were from France. The use of aspirin was lower in France than in other Western European countries (74.5% vs. 86.9%, respectively), whereas use of thienopyridines (48.5% vs. 21.7%), oral anticoagulants (12.3% vs. 9.0%) and lipid-lowering drugs (95.8% vs. 92.5%) was higher. Beta-blockers were used in 73% of both groups. Angina was less prevalent in France (6.3% vs. 15.5%) and French patients showed higher levels of physical activity than their counterparts in Western Europe. The management of patients with stable CAD in France appears favourable, with good adherence to guideline-based therapies, but there remains room for improvement in terms of symptom and risk factor control. Copyright © 2014. Published by Elsevier Masson SAS.

77 FR 64775 - New Mailing Standards for Domestic Mailing Services Products

Science.gov (United States)

2012-10-23

...'s Web site at www.prc.gov . The Postal Service's proposed rule includes several mail classification... Tracing \\TM\\ We are removing language concerning the old Confirm[supreg] service from DMM 503.15.0, because all Confirm subscriptions will end by January of 2013. IMb Tracing now provides a service similar...

31 CFR 560.508 - Telecommunications and mail transactions authorized.

Science.gov (United States)

2010-07-01

... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Telecommunications and mail... REGULATIONS Licenses, Authorizations and Statements of Licensing Policy § 560.508 Telecommunications and mail... telecommunications and mail between the United States and Iran are authorized. For purposes of this section, the term...

19 CFR 145.2 - Mail subject to Customs examination.

Science.gov (United States)

2010-04-01

... 19 Customs Duties 2 2010-04-01 2010-04-01 false Mail subject to Customs examination. 145.2 Section 145.2 Customs Duties U.S. CUSTOMS AND BORDER PROTECTION, DEPARTMENT OF HOMELAND SECURITY; DEPARTMENT OF THE TREASURY (CONTINUED) MAIL IMPORTATIONS General Provisions § 145.2 Mail subject to Customs...

Energy in France

International Nuclear Information System (INIS)

Benard, M.

1992-01-01

Geography and clear political leadership have combined to put France in the forefront of both nuclear and hydro-electric generation and energy efficiency so that about 90% of France's electricity is generated by non-fossil fuels. This article explains how and why France has developed its energy mix. (Author)

Cell cycle-regulated expression of mammalian CDC6 is dependent on E2F

DEFF Research Database (Denmark)

Hateboer, G; Wobst, A; Petersen, B O

1998-01-01

The E2F transcription factors are essential regulators of cell growth in multicellular organisms, controlling the expression of a number of genes whose products are involved in DNA replication and cell proliferation. In Saccharomyces cerevisiae, the MBF and SBF transcription complexes have...... of this gene is dependent on E2F. In vivo footprinting data demonstrate that the identified E2F sites are occupied in resting cells and in exponentially growing cells, suggesting that E2F is responsible for downregulating the promoter in early phases of the cell cycle and the subsequent upregulation when cells...

Pressure-induced magnetic collapse and metallization of TlF e1.6S e2

Science.gov (United States)

Naumov, P. G.; Filsinger, K.; Shylin, S. I.; Barkalov, O. I.; Ksenofontov, V.; Qi, Y.; Palasyuk, T.; Schnelle, W.; Medvedev, S. A.; Greenblatt, M.; Felser, C.

2017-08-01

The crystal structure, magnetic ordering, and electrical resistivity of TlF e1.6S e2 were studied at high pressures. Below ˜7 GPa , TlF e1.6S e2 is an antiferromagnetically ordered semiconductor with a ThC r2S i2 -type structure. The insulator-to-metal transformation observed at a pressure of ˜7 GPa is accompanied by a loss of magnetic ordering and an isostructural phase transition. In the pressure range ˜7.5 -11 GPa a remarkable downturn in resistivity, which resembles a superconducting transition, is observed below 15 K. We discuss this feature as the possible onset of superconductivity originating from a phase separation in a small fraction of the sample in the vicinity of the magnetic transition.

Um depoimento francês sobre a Inquisição em Portugal no século XVIII

Directory of Open Access Journals (Sweden)

Vitor Ramos

1963-06-01

Full Text Available Em 1762 foi publicado em Londres um veemente panfleto de ataque à Inquisição escrito em francês por um português exilado, que o Santo Ofício, no ano anterior, queimara em estátua, no último Auto da Fé realizado em Portugal. Trata-se de Le Chevalier d'Oliveyra brulé en effigie comine Hérétique. Comment et pourquoi? (1 obra de Francisco Xavier de Oliveira. Êste autor, cujo afastamento de Portugal, durante 51 anos, constitui o caso de mais longo exílio de escritor lusitano, nunca abdicou da sua nacionalidade, nem da língua materna, nem do interêsse pelos problemas do seu país, e se utilizou o francês na maior parte da sua obra fê-lo por razões estratégi-cas, dada a difusão que esta língua permitia na época aos ideais que pretendia espalhar.

2003 annual results of EdF group; Resultats annuels 2003 du groupe EDF

Energy Technology Data Exchange (ETDEWEB)

NONE

2004-03-01

The Electricite de France (EdF) group Board of Directors, meeting on March 11, 2004, under the Chairmanship of Francois Roussely, reviewed the audited consolidated financial statements for the year ended 12/31/2003. This document presents the consolidated results of EdF group for 2003: consolidated financial statements, highlights of the year, focus on 2003 events, commercial results, EDF in Europe and worldwide, EDF France highlights, key figures. (J.S.)

Tobacco industry marketing: an analysis of direct mail coupons and giveaways.

Science.gov (United States)

Brock, Betsy; Schillo, Barbara A; Moilanen, Molly

2015-09-01

Despite marketing prohibitions, tobacco company marketing expenditures in the USA have continued to grow with tobacco companies shifting focus towards point-of-sale-marketing and direct marketing to consumers through the mail and on the web. The purpose of this observational study was to investigate the content of direct marketing sent in response to registrations on select industry websites. An analysis of 659 tobacco company direct mail marketing pieces received between July 2011 and June 2012 was conducted. Mailings were coded for type and value of tobacco coupons, type of tobacco products promoted with coupons and number and type of giveaways offered. The most common type of mailing was tobacco coupon distribution; 86.5% of the mailings contained at least one coupon. Mailings with coupons had an average estimated coupon value of $4.17. The total coupon value of each mailing varied by the type of coupon offer and product promoted. The Camel and Marlboro coupon mailings heavily promoted snus, with over half of Camel coupon mailings (60.9%) and nearly half (44.8%) of Marlboro coupon mailings promoting snus alone. In addition, 47.9% of Marlboro coupon mailings and 11.4% of Camel mailings promoted snus alongside cigarettes. Tobacco companies use direct mail marketing to communicate with consumers and provide valuable tobacco coupons. More research is needed to understand the content of these mailings and how they are used by tobacco consumers in order to develop effective policy solutions. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

Comparison of foE and M(3000)F2 variability at Ibadan, Singapore and Slough

Science.gov (United States)

Somoye, E. O.; Onori, E. O.; Akala, A. O.

2013-01-01

The variability, VR, of critical frequency of E-layer, foE, and ionospheric propagation factor, M(3000)F2 at Ibadan (7.4°N, 3.9°E, 6°S dip) is investigated for local time, seasonal and solar cycle variations. Latitudinal influence of these characteristics is sought by comparison with foE VR and M(3000)F2 VR of Slough ( 51.5°N, 359.4°E, 66.5°N dip) in the European sector, and Singapore (1.3°N,103.8°E, 17.6°S dip) in the Asian sector. While the pattern of foE VR is similar to those of other F2 characteristics with characteristic peaks around dawn and dusk, M(3000)F2 VR shows no clear diurnal trend.A lower bound of foE VR is usually 3% while the maximum VR ranges between 8% and13% at post-sunrise and pre-sunset hours at all the epochs, M(3000)F2 VR is however lower during MSA (about 9%) than during LSA and HSA when it is 4% to about 12-14%. Generally, daytime M(3000)F2 VR is greater than that of foE VR by between 5% and 10%. Furthermore, no latitudinal difference is observed in both characteristics during both HSA and MSA. While nighttime M(3000)F2 VR is about half that of nighttime foF2 VR (the critical frequency of F2-layer ) VR, daytime VR of both characteristics are about equal during the three epochs at Ibadan. For Slough, nighttime M(3000)F2 VR and nighttime foF2 VR as well as the daytime VR of both characteristics are about equal. This difference is most likely due to latitudinal effect.

78 FR 76533 - New Mailing Standards for Domestic Mailing Services Products

Science.gov (United States)

2013-12-18

... accountable mail, including a Return Receipt (Form 3811) purchased with the applicable extra service. Although..., and for firearms to require a Form 1508 submission with the claim. Also, gift cards, most of which are... delivery record by purchasing a return receipt. Bulk proof of delivery service (6.0) is also available if...

Oct3/4 directly regulates expression of E2F3a in mouse embryonic stem cells

International Nuclear Information System (INIS)

Kanai, Dai; Ueda, Atsushi; Akagi, Tadayuki; Yokota, Takashi; Koide, Hiroshi

2015-01-01

Embryonic stem (ES) cells, derived from the inner cell mass of blastocysts, have a characteristic cell cycle with truncated G1 and G2 phases. Recent findings that suppression of Oct3/4 expression results in a reduced proliferation rate of ES cells suggest the involvement of Oct3/4 in the regulation of ES cell growth, although the underlying molecular mechanism remains unclear. In the present study, we identified E2F3a as a direct target gene of Oct3/4 in ES cells. Oct3/4 directly bound to the promoter region of the E2F3a gene and positively regulated expression of E2F3a in mouse ES cells. Suppression of E2F3a activity by E2F6 overexpression led to the reduced proliferation in ES cells, which was relieved by co-expression of E2F3a. Furthermore, cell growth retardation caused by loss of Oct3/4 was rescued by E2F3a expression. These results suggest that Oct3/4 upregulates E2F3a expression to promote ES cell growth. - Highlights: • Oct3/4 positively regulates E2F3a expression in ES cells. • Oct3/4 binds to the promoter region of the E2F3a gene. • Overexpression of E2F6, an inhibitor of E2F3a, reduces ES cell growth. • E2F3a recovers growth retardation of ES cells caused by Oct3/4 reduction

Oct3/4 directly regulates expression of E2F3a in mouse embryonic stem cells

Energy Technology Data Exchange (ETDEWEB)

Kanai, Dai; Ueda, Atsushi; Akagi, Tadayuki; Yokota, Takashi; Koide, Hiroshi, E-mail: hkoide@med.kanazawa-u.ac.jp

2015-04-10

Embryonic stem (ES) cells, derived from the inner cell mass of blastocysts, have a characteristic cell cycle with truncated G1 and G2 phases. Recent findings that suppression of Oct3/4 expression results in a reduced proliferation rate of ES cells suggest the involvement of Oct3/4 in the regulation of ES cell growth, although the underlying molecular mechanism remains unclear. In the present study, we identified E2F3a as a direct target gene of Oct3/4 in ES cells. Oct3/4 directly bound to the promoter region of the E2F3a gene and positively regulated expression of E2F3a in mouse ES cells. Suppression of E2F3a activity by E2F6 overexpression led to the reduced proliferation in ES cells, which was relieved by co-expression of E2F3a. Furthermore, cell growth retardation caused by loss of Oct3/4 was rescued by E2F3a expression. These results suggest that Oct3/4 upregulates E2F3a expression to promote ES cell growth. - Highlights: • Oct3/4 positively regulates E2F3a expression in ES cells. • Oct3/4 binds to the promoter region of the E2F3a gene. • Overexpression of E2F6, an inhibitor of E2F3a, reduces ES cell growth. • E2F3a recovers growth retardation of ES cells caused by Oct3/4 reduction.

BEBAN JARINGAN SAAT MENGAKSES EMAIL DARI BEBERAPA MAIL SERVER

Directory of Open Access Journals (Sweden)

Husni Thamrin

2017-01-01

Full Text Available Expensive internet facilities require prudent in its use both as a source of information and communication media. This paper discusses observations of the perceived burden of network bandwidth when accessing some of the mail server using a webmail application. Mail server in question consists of three commercial server and 2 non-commercial server. Data when it download home page, while logged in, open the email, and during idle logout recorded with sniffer Wireshark. Observations in various situations and scenarios indicate that access Yahoo email gives the network load is very high while the SquirrelMail gives the network load is very low than 5 other mail servers. For an institution, use a local mail server (institutional is highly recommended in the context of banddwidth savings.

The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1

DEFF Research Database (Denmark)

Jenal, Mathias; Trinh, Emmanuelle; Britschgi, Christian

2009-01-01

to the HIC1 promoter was shown by chromatin immunoprecipitation assays in human TIG3 fibroblasts expressing tamoxifen-activated E2F1. In agreement, activation of E2F1 in TIG3-E2F1 cells markedly increased HIC1 expression. Interestingly, expression of E2F1 in the p53(-/-) hepatocellular carcinoma cell line...

1 CFR 5.7 - Delivery and mailing.

Science.gov (United States)

2010-01-01

... 1 General Provisions 1 2010-01-01 2010-01-01 false Delivery and mailing. 5.7 Section 5.7 General Provisions ADMINISTRATIVE COMMITTEE OF THE FEDERAL REGISTER THE FEDERAL REGISTER GENERAL § 5.7 Delivery and mailing. The Government Printing Office shall distribute the Federal Register by delivery or by deposit at...

Trabalhador com deficiência física: fragilidades e agravos autorreferidos

Directory of Open Access Journals (Sweden)

Débora Ribas Leal

2013-02-01

Full Text Available Este estudo teve como objetivo investigar fragilidades e agravos vivenciados por trabalhadores com deficiência física no seu ambiente de trabalho. Trata-se de um estudo de caso, de caráter descritivo, de abordagem qualitativa. Os dados foram coletados junto a oito trabalhadores com deficiência física e analisados mediante análise temática. A maioria dos sujeitos pesquisados refere ter encontrado dificuldades na busca do emprego e mencionam o preconceito e a acessibilidade como obstáculos. A maioria não identifica riscos para adoecimento no ambiente de trabalho. As pessoas com deficiência física devem ter conhecimentos acerca de seus direitos e sobre os riscos ocupacionais a que estão expostos, a fim de facilitar meios para a consolidação de uma sociedade cada vez mais inclusiva e promotora de ambiências saudáveis. Os profissionais de saúde devem fazer uma profunda reflexão a fim de que sejam colaboradores para a inclusão saudável de pessoas com deficiência em seus ambientes de trabalho.

77 FR 65279 - Domestic Competitive Products Pricing and Mailing Standards Changes

Science.gov (United States)

2012-10-26

... POSTAL SERVICE 39 CFR Part 111 Domestic Competitive Products Pricing and Mailing Standards Changes... and mailing standards for the following competitive products: Express Mail[supreg], Priority Mail.... SUPPLEMENTARY INFORMATION: This final rule describes new prices and product features for competitive products...

(e,e'f) coincidence experiments for fission decay of giant resonances in 235,238U

International Nuclear Information System (INIS)

Weber, T.; Heil, R.D.; Kneissl, U.; Pecho, W.; Wilke, W.; Emrich, H.J.; Kihm, T.; Knoepfle, K.T.

1988-01-01

Extending previous work on 238 U, 235 U(e,e'f) coincidence data were taken at 4 momentum transfers yielding both E1, E2/E0 and E3 form factors and the respective multipole strength distributions in the giant resonance region of 238 U (4 x x /Γ a is obtained as a function of excitation energy for separated multipoles. The giant E2 resonance exhibits an increased symmetric fission contribution compared to E1 and E3 resonances. (orig.)

9. mail Moskvasse minna ei tohi / Heiki Suurkask

Index Scriptorium Estoniae

Suurkask, Heiki, 1972-

2004-01-01

Autori arvates tähendaks Eesti Vabariigi presidendi visiit 9. mail Moskvasse sõjaroimarite õigeksmõistmist. Lisa: Kas Eesti president peaks minema 9. mail Moskvasse? Küsimusele vastavad: Heiki Ahonen, Dimitri Klenski, Karmo Tüür

Caliciviruses differ in their functional requirements for eIF4F components

DEFF Research Database (Denmark)

Chaudhry, Y.; Nayak, A.; Bordeleau, M-E.

2006-01-01

proteins can interact directly with the initiation factors eIF4E and eIF3. Translation initiation on feline calicivirus (FCV) RNA requires eIF4E because it is inhibited by recombinant 4E-BP1. However, to date, there have been no functional studies carried out with respect to norovirus translation...... translation require the RNA helicase component of the eIF4F complex, namely eIF4A, because translation was sensitive (albeit to different degrees) to a dominant negative form and to a small molecule inhibitor of eIF4A (hippuristanol). These results suggest that calicivirus RNAs differ with respect...... to their requirements for the components of the eIF4F translation initiation complex....

Effects of a conducting E layer on classical F region cross-field plasma diffusion

International Nuclear Information System (INIS)

Vickrey, J.F.; Kelley, M.C.

1982-01-01

The rate of cross-field plasma diffusion in the F region ionosphere is significantly increased when the magnetic field lines thread a highly conducting E region below. This reduces the lifetime of small-scale F region electron density irregularities in the polar ionosphere where the presence of a highly conducting E region is comonplace. A simple mmodel is developed to describe the effects of a conducting E layer on classical F region plasma diffusion. In the absence of an E region, the difference in ion and electron diffusion rates leads to a charge separation and, hence, to an electrostatic field that retards ion diffusion. When the highly conducting magnetic field lines are tied to a conducting E region, however, electrons can flow along B to reduce the ambipolar diffusion electric field, and ions can proceed perpendicular to B at a rate approaching their own (higher) diffusion velocity. It is shown that the enhanced total diffusion rate that results depends strongly on the height of the F layer and on the ratio of the E to F region Pedersen conductivities

Induction of S-phase entry by E2F transcription factors depends on their nuclear localization

DEFF Research Database (Denmark)

Müller, H; Moroni, M C; Vigo, E

1997-01-01

The E2F transcription factors are essential for regulating the correct timing of activation of several genes whose products are implicated in cell proliferation and DNA replication. The E2Fs are targets for negative regulation by the retinoblastoma protein family, which includes pRB, p107, and p130......, and they are in a pathway that is frequently found altered in human cancers. There are five members of the E2F family, and they can be divided into two functional subgroups. Whereas, upon overexpression, E2F-1, -2, and -3 induce S phase in quiescent fibroblasts and override G1 arrests mediated by the p16INK4A tumor...... suppressor protein or neutralizing antibodies to cyclin D1, E2F-4 and -5 do not. Using E2F-1 and E2F-4 as representatives of the two subgroups, we showed here, by constructing a set of chimeric proteins, that the amino terminus of E2F-1 is sufficient to confer S-phase-inducing potential as well...

Biologia e tabela de vida de fertilidade do pulgão-preto em cultivares de videira

Directory of Open Access Journals (Sweden)

Cléber Antonio Baronio

2014-09-01

Full Text Available O objetivo deste trabalho foi avaliar a biologia e a tabela de vida de fertilidade do pulgão-preto da videira [Aphis illinoisensis (Hemiptera: Aphididae], em mudas das cultivares de Vitis labrusca Bordô, e de V. vinifera Cabernet Franc, Itália e Moscato Bianco. O experimento foi conduzido em 50 minigaiolas de confinamento, com um inseto em cada gaiola por tratamento, fixadas em mudas de videira mantidas em câmara de crescimento do tipo fitotron (a 25±1°C, umidade relativa de 75±10% e fotófase de 14 horas. Avaliaram-se diariamente a duração e a viabilidade ninfal, a fecundidade e a longevidade do período reprodutivo da espécie. O pulgão-preto da videira completou o ciclo biológico nas mudas das mencionadas cultivares, com duração da fase de ninfa de 7,9±0,3, 6,8±0,2, 6,2±0,2 e 6,7±0,2 dias, e viabilidade de 58, 82, 98 e 80% para 'Bordô', 'Cabernet Franc', 'Itália' e 'Moscato Bianco', respectivamente. 'Cabernet Franc' e 'Moscato Bianco' foram mais favoráveis ao desenvolvimento do pulgão-preto, com base na tabela de vida de fertilidade, com 51,3 e 55,6 descendentes por fêmea, por geração, respectivamente. 'Bordô' foi a menos adequada ao desenvolvimento do afídeo, com 12,55 descendentes por fêmea, por geração, o que indica resistência do tipo antibiose ou não preferência do inseto pela cultivar.

Memória Auditiva-Verbal e Funções Executivas em Crianças Bilingues (Português Europeu/Francês) e Monolingues (Português Europeu) dos 10 aos 11 anos de idade

OpenAIRE

Spínola, Jennifer Gomes

2011-01-01

O principal objectivo deste estudo foi verificar se o desempenho de crianças bilingues difere das monolingues no que concerne à memória auditiva-verbal e funções executivas. Neste estudo de carácter descritivo-comparativo participaram 70 estudantes do 5º ano de escolaridade, com idades compreendidas entre os 10 e 11 anos de idade. (M= 10,24; DP= 0,43). Dos 70 estudantes, 30 são bilingues (Português Europeu/ Francês) e frequentam o ensino bilingue e 40 são monolingues (Português Europeu) e fre...

Controle postural e atividade física em crianças eutróficas, com sobrepeso e obesas

Directory of Open Access Journals (Sweden)

Jessica Caroliny de Jesus Neves

Full Text Available RESUMO Introdução: A obesidade infantil vem crescendo nos últimos anos e ocorre, provavelmente, em função da modificação dos hábitos de vida, como sedentarismo e consumo de alimentos inadequados. Na população com excesso de peso, o controle postural, que é um pré-requisito para diversas posturas e atividades, pode ser modificado. Objetivos: Avaliar e comparar o controle postural e a atividade física em crianças eutróficas, com sobrepeso e obesas com oito anos de idade da Rede Municipal de Ensino de Londrina, PR. Além disso, verificar associação entre atividade física e classificação nutricional. Métodos: A amostra foi composta por 346 crianças, divididas em três grupos: eutróficas (n = 205, com sobrepeso (n = 69 e obesas (n = 72, que responderam ao questionário de atividade física para crianças (PAQ-C. A avaliação do controle postural foi realizada na plataforma de força, de preferência, em posição unipodal. Resultados: A prevalência de crianças acima do peso foi de 40,7% e de sedentárias, 82,9%, com mediana de três horas diárias em frente à TV. As crianças apresentaram, na posição unipodal, área de COP de 13,41 ± 6,77 cm2, o grupo eutrófico apresentou área de COP de 13,97 ± 6,67 cm2, o grupo com sobrepeso, 12,34 ± 5,71 cm2 e os obesos 13,59 ± 7,94 cm2 (p = 0,785. As meninas tiveram melhor desempenho no controle postural do que os meninos (p = 0,000. A frequência AP (Hz e a velocidade ML (cm/s apresentaram diferença estatisticamente significante (p = 0,033 e p = 0,016, respectivamente. Também foi identificada associação entre crianças eutróficas e com sobrepeso e atividade física (p = 0,013 ; X2 = 6,186; Odds Ratio = 0,308; p = 0,020; X2 = 5,38, Odds Ratio = 0,293, respectivamente. Conclusão: Há alta prevalência de excesso de peso e sedentarismo. O excesso de peso não afetou a área de COP (cm2, mas interferiu na frequência AP e na velocidade ML. A atividade física mostrou-se fator

Dissociative scattering of low-energy SiF{sub 3}{sup +} and SiF{sup +} ions (5-200 eV) on Cu(100) surface

Energy Technology Data Exchange (ETDEWEB)

Yamamoto, Hiroyuki; Baba, Yuji; Sasaki, T A [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

1997-03-01

Dissociative scattering of molecular SiF{sub 3}{sup +} and SiF{sup +} ions from a Cu(100) single crystal surface has been investigated in the incident energy range from 5 eV to 200 eV with a scattering angle of 77deg. The scattered ion intensity of dissociative ions and parent molecular ions were measured as a function of incident ion energy. The observed data show that onset energies of dissociation for SiF{sub 3}{sup +} and SiF{sup +} ions are 30 eV and 40 eV, respectively. The obtained threshold energies are consistent with a impulsive collision model where the dissociation of incident ion is caused by vibrational excitation during collision. (author)

Sibling rivalry in the E2F family.

Science.gov (United States)

Trimarchi, Jeffrey M; Lees, Jacqueline A

2002-01-01

The E2F transcription factor family determines whether or not a cell will divide by controlling the expression of key cell-cycle regulators. The individual E2Fs can be divided into distinct subgroups that act in direct opposition to one another to promote either cellular proliferation or cell-cycle exit and terminal differentiation. What is the underlying molecular basis of this 'push-me-pull-you' regulation, and what are its biological consequences?

E2F3a gene expression has prognostic significance in childhood acute lymphoblastic leukemia.

Science.gov (United States)

Wang, Kai-Ling; Mei, Yan-Yan; Cui, Lei; Zhao, Xiao-Xi; Li, Wei-Jing; Gao, Chao; Liu, Shu-Guang; Jiao, Ying; Liu, Fei-Fei; Wu, Min-Yuan; Ding, Wei; Li, Zhi-Gang

2014-10-01

To study E2F3a expression and its clinical significance in children with acute lymphoblastic leukemia (ALL). We quantified E2F3a expression at diagnosis in 148 children with ALL by real-time PCR. In the test cohort (n = 48), receiver operating characteristic (ROC) curve was used to find the best cut-off point to divide the patients into E2F3a low- and high-expression groups. The prognostic significance of E2F3a expression was investigated in the test cohort and confirmed in the validation cohort (n = 100). The correlations of E2F3a expression with the clinical features and treatment outcome of these patients were analyzed. ROC curve analysis indicated that the best cut-off point of E2F3a expression was 0.3780. In the test cohort, leukemia-free survival (LFS) and event-free survival (EFS) of the low-expression group were lower than those of the high-expression group (log rank: P = 0.026 for both). This finding was verified in the validation cohort. LFS, EFS, and overall survival were also lower in the low-expression group than in the high-expression group (log rank, P = 0.015, 0.008, and 0.002 respectively). E2F3a low expression was correlated with the existence of BCR-ABL fusion. An algorithm composed of E2F3a expression and minimal residual disease (MRD) could predict relapse or induction failure more precisely than current risk stratification. These results were still significant in the ALL patients without BCR-ABL fusion. Low expression of E2F3a was associated with inferior prognosis in childhood ALL. An algorithm composed of E2F3a expression and MRD could predict relapse or induction failure more precisely than that of the current risk stratification. © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Identification of an ovine atadenovirus gene whose product activates the viral E2 promoter: possible involvement of E2F-1

International Nuclear Information System (INIS)

Kuemin, Daniel; Hofmann, Christian; Uckert, Wolfgang; Both, Gerald W.; Loeser, Peter

2004-01-01

Activation of the adenoviral E2 promoter is an early step in adenovirus gene expression. For members of the mast- and aviadenoviruses, this requires induction of the cellular transcription factor E2F by virally encoded gene products such as E1A, E4orf6/7 and orf22/GAM-1. The newly recognized genus atadenovirus, of which the ovine isolate OAdV is the prototype, lacks any sequence homology to those genes. To find a possible link between E2 promoter activation and OAdV gene expression, we utilized a screening method to search for genes within the OAdV genome that were capable of stimulating the viral E2 promoter. One such gene, E43, was identified within the proposed E4 region toward the right-hand end of the OAdV genome. The E43 gene product was also found to be capable of stimulating E2F-1-dependent gene expression. A closer inspection of the E2 promoter revealed the presence of a non-palindromic E2F binding site within the OAdV E2 promoter. Mutation of this site markedly reduced both E2F-1- and E43-dependent promoter activation. Moreover, a direct protein-protein interaction of the E43 gene product with E2F, but not with the retinoblastoma protein pRb, suggested a possible cooperation between these two proteins in activating the E2 promoter. The importance of the E43 gene product for virus replication is also underlined by the finding that an OAdV recombinant with a functionally inactivated E43 gene showed severely inhibited virus growth

Stochastic E2F activation and reconciliation of phenomenological cell-cycle models.

Science.gov (United States)

Lee, Tae J; Yao, Guang; Bennett, Dorothy C; Nevins, Joseph R; You, Lingchong

2010-09-21

The transition of the mammalian cell from quiescence to proliferation is a highly variable process. Over the last four decades, two lines of apparently contradictory, phenomenological models have been proposed to account for such temporal variability. These include various forms of the transition probability (TP) model and the growth control (GC) model, which lack mechanistic details. The GC model was further proposed as an alternative explanation for the concept of the restriction point, which we recently demonstrated as being controlled by a bistable Rb-E2F switch. Here, through a combination of modeling and experiments, we show that these different lines of models in essence reflect different aspects of stochastic dynamics in cell cycle entry. In particular, we show that the variable activation of E2F can be described by stochastic activation of the bistable Rb-E2F switch, which in turn may account for the temporal variability in cell cycle entry. Moreover, we show that temporal dynamics of E2F activation can be recast into the frameworks of both the TP model and the GC model via parameter mapping. This mapping suggests that the two lines of phenomenological models can be reconciled through the stochastic dynamics of the Rb-E2F switch. It also suggests a potential utility of the TP or GC models in defining concise, quantitative phenotypes of cell physiology. This may have implications in classifying cell types or states.

Introducing the C.E.P.N. (Center for the assessment of protection in the nuclear field)

International Nuclear Information System (INIS)

Jammet, H.P.

1981-01-01

The center for the assessment of protection in the nuclear field (C.E.P.N.) was set up by Electricite de France (E.D.F.) and the Commissariat a l'Energie Atomique (C.E.A.) in May 1976. Dr JAMMET, one of its promoters, relates the circumstances and motivations of its creation and presents the general lines of the purposes and programmes presently developed by the center [fr