Kinetic characterization of glucose aerodehydrogenase from Aspergillus niger EMS-150-F after optimizing the dose of mutagen for enhanced production of enzyme

Directory of Open Access Journals (Sweden)

Huma Umbreen

2013-12-01

Full Text Available In the present study enhanced production of glucose aerodehydrogenase from Aspergillus niger has been achieved after optimizing the dose of chemical mutagen ethyl methane sulfonate (EMS that has not been reported earlier. Different doses of mutagen were applied and a strain was developed basing upon the best production. The selected strain Aspergillus niger EMS-150-F was optimized for nutrient requirements in order to produce enzyme through fermentation and the results showed the best yield at 2% corn steep liquor (CSL, 36 hours fermentation time, pH 5, 30°C temperature, 0.3% KH2PO4, 0.3% urea and 0.06% CaCO3. The enzyme was then purified and resulted in 57.88 fold purification with 52.12% recovery. On kinetic characterization, the enzyme showed optimum activity at pH 6 and temperature 30°C. The Michaelis-Menton constants (Km, Vmax, Kcat and Kcat/Km were 20 mM, 45.87 U mL-1, 1118.81 s-1 and 55.94 s-1 mM-1, respectively. The enzyme was found to be thermaly stable and the enthalpy and free energy showed an increase with increase in temperature and ΔS* was highly negative proving the enzyme from A. niger EMS-150-F resistant to temperature and showing a very little disorderliness.

Weasel works SA-150: Design study of a 100 to 150 passenger transport aircraft

Science.gov (United States)

Alkema, Kevin; Comeaux, Michael; Gilbert, Timothy; Para, Victor; Toepfer, George

1993-01-01

As the year 2000 rapidly approaches, the airlines are faced with an extremely competitive and environmentally restrictive marketplace. In order to survive, commercial air carriers will need to find new ways to lower their direct operating costs, increase load factors and comply with tightening federal and international constraints. The SA-150 has been designed to meet these demands by focusing on the areas of aerodynamic efficiency, an improved level of passenger comfort, and a limited application of advanced technology. The SA-150 has been optimized for a 500 nmi. mission to help the airlines meet the challenges of the short haul, quick turnaround flight. With a maximum capacity of 124 passengers, and full baggage, the SA-150 is also capable of covering a range of 1500 nmi. This additional range capability will provide the airlines with flexibility when scheduling their routes. The aircraft features a 'V' tail, fly-by-wire system and is powered by two turbofans mounted under a twelve aspect ratio wing. The SA-150 will have an initial production run of 800 units and have a purchase price of $37.7 million in 1993 dollars.

Operational Readiness Review Final Report For F-Canyon Restart. Phase 1

Energy Technology Data Exchange (ETDEWEB)

McFarlane, A.F.; Spangler, J.B.

1995-04-05

An independent WSRC Operational Readiness Review was performed for the restart of Phase 1 processing in F-Canyon, Building 221-F. Readiness to restart the Second Plutonium Cycle process and solvent recovery was assessed. The ORR was conducted by an ORR board of ten members with the support of a subject matter expert. The chairman and four members were drawn from the Operational Safety Evaluation Department, ESH& QA Division; additional members were drawn from other WSRC divisions, independent of the F-Canyon operating division (NMPD). Based on the results of the readiness verification assessments performed according to the ORR plan and the validation of pre-restart corrective actions, the WSRC independent ORR Board has concluded that the facility has achieved the state of readiness committed to in the Restart Plan. Also, based on the scope of the ORR, it is the opinion of the board that F-Canyon Phase 1 processes can be restarted without undue risk to the safety of the public and onsite workers and without undue risk to the environment.

Operational Readiness Review Final Report For F-Canyon Restart. Phase 1

International Nuclear Information System (INIS)

McFarlane, A.F.; Spangler, J.B.

1995-01-01

An independent WSRC Operational Readiness Review was performed for the restart of Phase 1 processing in F-Canyon, Building 221-F. Readiness to restart the Second Plutonium Cycle process and solvent recovery was assessed. The ORR was conducted by an ORR board of ten members with the support of a subject matter expert. The chairman and four members were drawn from the Operational Safety Evaluation Department, ESH ampersand QA Division; additional members were drawn from other WSRC divisions, independent of the F-Canyon operating division (NMPD). Based on the results of the readiness verification assessments performed according to the ORR plan and the validation of pre-restart corrective actions, the WSRC independent ORR Board has concluded that the facility has achieved the state of readiness committed to in the Restart Plan. Also, based on the scope of the ORR, it is the opinion of the board that F-Canyon Phase 1 processes can be restarted without undue risk to the safety of the public and onsite workers and without undue risk to the environment

45 CFR 150.313 - Market conduct examinations.

Science.gov (United States)

2010-10-01

..., or the operation of a non-Federal governmental plan, involving the review of one or more (or a combination) of a responsible entity's business or operational affairs, or both, to verify compliance with... Non-Federal Governmental Plans-Civil Money Penalties § 150.313 Market conduct examinations. (a...

40 CFR 68.150 - Submission.

Science.gov (United States)

2010-07-01

... Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) AIR PROGRAMS (CONTINUED) CHEMICAL ACCIDENT PREVENTION PROVISIONS Risk Management Plan § 68.150 Submission. (a) The owner or operator shall... processes. The RMP shall be submitted in the method and format to the central point specified by EPA as of...

RCV-150 remotely operated vehicle and its operation in the hostile undersea environment

International Nuclear Information System (INIS)

Billet, A.B.

1984-01-01

The past decade has shown a dramatic increase in the use of unmanned tethered vehicles in worldwide marine fields. These are used for inspection, debris removal and object retrieval. The RCV-150/sup chemical bond/ system is an example of these advanced technology vehicles. With the requirements of high maneuverability and unusual inspection a responsive, high performance, compact hydraulic system was developed. The hydraulic system is powered by an electric motor-driven pump which provides hydraulic power to the four thruster motors and to the five-function manipulator work arm

Safety analysis -- 200 Area Savannah River Plant, F-Canyon Operations. Supplement 4

Energy Technology Data Exchange (ETDEWEB)

Beary, M.M.; Collier, C.D.; Fairobent, L.A.; Graham, R.F.; Mason, C.L.; McDuffee, W.T.; Owen, T.L.; Walker, D.H.

1986-02-01

The F-Canyon facility is located in the 200 Separations Area and uses the Purex process to recover plutonium from reactor-irradiated uranium. The irradiated uranium is normally in the form of solid or hollow cylinders called slugs. These slugs are encased in aluminum cladding and are sent to the F-Canyon from the Savannah River Plant (SRP) reactor areas or from the Receiving Basin for Offsite Fuels (RBOF). This Safety Analysis Report (SAR) documents an analysis of the F-Canyon operations and is an update to a section of a previous SAR. The previous SAR documented an analysis of the entire 200 Separations Area operations. This SAR documents an analysis of the F-Canyon and is one of a series of documents for the Separations Area as specified in the Savannah River Implementation Plans. A substantial amount of the information supporting the conclusions of this SAR is found in the Systems Analysis. Some F-Canyon equipment has been updated during the time between the Systems Analysis and this SAR and a complete description of this equipment is included in this report. The primary purpose of the analysis was to demonstrate that the F-Canyon can be operated without undue risk to onsite or offsite populations and to the environment. In this report, risk is defined as the expected frequency of an accident, multiplied by the resulting radiological consequence in person-rem. The units of risk for radiological dose are person-rem/year. Maximum individual exposure values have also been calculated and reported.

33 CFR 150.815 - How must casualties be reported?

Science.gov (United States)

2010-07-01

..., gas freeing, dry-docking, or demurrage of the port, vessel, or aircraft. (b) The notice under... (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Reports and Records Reports § 150.815 How must..., operator, or person in charge of a deepwater port must notify the nearest Sector, Marine Safety Unit, or...

Fission product poisoning in KS-150 reactor operation

International Nuclear Information System (INIS)

Rana, S.B.

1978-01-01

A three-dimensional model of the KS-150 reactor was used to study reactivity changes induced by reactor poisoning with fission products Xe 135 and Sm 149 . A comparison of transients caused by the poisoning showed the following differences: (1) the duration of the transient Xe poisoning (2 days) is shorter by one order of magnitude than the duration of Sm poisoning (20 days); however, the level of Xe poisoning is greater approximately by one order than the level of the Sm poisoning; (2) the level of steady-state Xe poisoning depends on the output level of the reactor; steady-state Sm poisoning does not depend on this level; (3) following reactor shutdown Xe poisoning may increase to the maximum value of up to Δrhosub(Xe)=20% and will then gradually decrease; Sm poisoning may reach maximum values of up to Δrhosub(Sm)=2% and does not decrease. (J.B.)

33 CFR 150.705 - What are the requirements for maintaining and inspecting aids to navigation?

Science.gov (United States)

2010-07-01

... maintaining and inspecting aids to navigation? 150.705 Section 150.705 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) DEEPWATER PORTS DEEPWATER PORTS: OPERATIONS Aids to Navigation § 150.705 What are the requirements for maintaining and inspecting aids to navigation? (a) All...

The O({alpha}{sup 3}{sub s}n{sub f}T{sup 2}{sub F}C{sub A,F}) contributions to the gluonic massive operator matrix elements

Energy Technology Data Exchange (ETDEWEB)

Bluemlein, Johannes; Hasselhuhn, Alexander [Deutsches Elektronen-Synchrotron (DESY), Zeuthen (Germany); Klein, Sebastian [Technische Hochschule Aachen (Germany). Inst. fuer Theoretische Physik E; Schneider, Carsten [Johannes Kepler Univ., Linz (Austria). Research Inst. for Symbolic Computation

2012-05-15

The O({alpha}{sub s}{sup 3}n{sub f}T{sub F}{sup 2}C{sub A,F}) terms to the massive gluonic operator matrix elements are calculated for general values of the Mellin variable N. These twist-2 matrix elements occur as transition functions in the variable flavor number scheme at NNLO. The calculation uses sum-representations in generalized hypergeometric series turning into harmonic sums. The analytic continuation to complex values of N is provided.

40 CFR 265.150 - State assumption of responsibility.

Science.gov (United States)

2010-07-01

..., STORAGE, AND DISPOSAL FACILITIES Financial Requirements § 265.150 State assumption of responsibility. (a) If a State either assumes legal responsibility for an owner's or operator's compliance with the... 40 Protection of Environment 25 2010-07-01 2010-07-01 false State assumption of responsibility...

Kurokawa 150-kW wind turbine generator demonstration; 150 kW Kurokawa furyoku hatsudensho ni tsuite

Energy Technology Data Exchange (ETDEWEB)

Okamoto, M; Shinohara, M; Sugiyama, T [Kansai Electric Power Co. Inc., Osaka (Japan)

1996-10-27

This paper presents the 150kW wind turbine generator erected at a site near Kurokawa dam lake of Kansai Electric Power Co. in Hyogo prefecture. This generator is composed of a horizontal-axis propeller with 3 blades of 27m in diameter and 36/27rpm, and a tower of 30m high. Harmony with the environment was also considered because of the site in a natural park area. Its demonstration test started in Oct. 1996 at annual mean wind velocity of 2m/s. Soft start was realized by controlling inrush current and preventing voltage drop in system interconnection by use of a thyristor circuit. The dual operation system was adopted of a 30kW small generator at lower wind velocity and a 150kW large one at higher velocity. Two kinds of brakes are used, and rotor revolution was reduced by air brake (blade tip spoiler). Mechanical disk brake works for the stopped rotor or emergency stopping. Even if the wind turbine was stopped by exterior factor, if no anomaly of the turbine is found, it automatically re-starts after removal of the factor. The generator is controlled from a remote control station 150km apart through NTT communication line. 6 figs., 2 tabs.

Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI

Science.gov (United States)

Fox, Michael D.; Qian, Tianyi; Madsen, Joseph R.; Wang, Danhong; Li, Meiling; Ge, Manling; Zuo, Huan-cong; Groppe, David M.; Mehta, Ashesh D.; Hong, Bo; Liu, Hesheng

2016-01-01

Noninvasive localization of brain function is used to understand and treat neurological disease, exemplified by pre-operative fMRI mapping prior to neurosurgical intervention. The principal approach for generating these maps relies on brain responses evoked by a task and, despite known limitations, has dominated clinical practice for over 20 years. Recently, pre-operative fMRI mapping based on correlations in spontaneous brain activity has been demonstrated, however this approach has its own limitations and has not seen widespread clinical use. Here we show that spontaneous and task-based mapping can be performed together using the same pre-operative fMRI data, provide complimentary information relevant for functional localization, and can be combined to improve identification of eloquent motor cortex. Accuracy, sensitivity, and specificity of our approach are quantified through comparison with electrical cortical stimulation mapping in eight patients with intractable epilepsy. Broad applicability and reproducibility of our approach is demonstrated through prospective replication in an independent dataset of six patients from a different center. In both cohorts and every individual patient, we see a significant improvement in signal to noise and mapping accuracy independent of threshold, quantified using receiver operating characteristic curves. Collectively, our results suggest that modifying the processing of fMRI data to incorporate both task-based and spontaneous activity significantly improves functional localization in pre-operative patients. Because this method requires no additional scan time or modification to conventional pre-operative data acquisition protocols it could have widespread utility. PMID:26408860

The O({alpha}{sub s}{sup 3}n{sub f}T{sub F}{sup 2}C{sub A,F}) contributions to the gluonic massive operator matrix elements

Energy Technology Data Exchange (ETDEWEB)

Bluemlein, Johannes, E-mail: johannes.bluemlein@desy.de [Deutsches Elektronen-Synchrotron, DESY, Platanenallee 6, D-15738 Zeuthen (Germany); Hasselhuhn, Alexander [Deutsches Elektronen-Synchrotron, DESY, Platanenallee 6, D-15738 Zeuthen (Germany); Klein, Sebastian [Institute for Theoretical Physics E, RWTH Aachen University, D-52056 Aachen (Germany); Schneider, Carsten [Research Institute for Symbolic Computation (RISC), Johannes Kepler University, Altenbergerstrasse 69, A-4040 Linz (Austria)

2013-01-11

The O({alpha}{sub s}{sup 3}n{sub f}T{sub F}{sup 2}C{sub A,F}) terms to the massive gluonic operator matrix elements are calculated for general values of the Mellin variable N using a new summation technique. These twist-2 matrix elements occur as transition functions in the variable flavor number scheme at NNLO. The calculation uses sum-representations in generalized hypergeometric series turning into harmonic sums. The analytic continuation to complex values of N is provided.

40 CFR 264.150 - State assumption of responsibility.

Science.gov (United States)

2010-07-01

... FACILITIES Financial Requirements § 264.150 State assumption of responsibility. (a) If a State either assumes legal responsibility for an owner's or operator's compliance with the closure, post-closure care, or... 40 Protection of Environment 25 2010-07-01 2010-07-01 false State assumption of responsibility...

40 CFR 261.150 - State assumption of responsibility.

Science.gov (United States)

2010-07-01

... Excluded Hazardous Secondary Materials § 261.150 State assumption of responsibility. (a) If a State either assumes legal responsibility for an owner's or operator's compliance with the closure or liability... 40 Protection of Environment 25 2010-07-01 2010-07-01 false State assumption of responsibility...

40 CFR 267.150 - State assumption of responsibility.

Science.gov (United States)

2010-07-01

... STANDARDIZED PERMIT Financial Requirements § 267.150 State assumption of responsibility. (a) If a State either assumes legal responsibility for an owner's or operator's compliance with the closure care or liability... 40 Protection of Environment 26 2010-07-01 2010-07-01 false State assumption of responsibility...

Operational stability of a compact 600-W KrF laser

International Nuclear Information System (INIS)

Borisov, V M; Vinokhodov, A Yu; Vodchits, V A; El'tsov, A V; Basting, D; Stamm, U; Voss, F

1998-01-01

The problem of the operational stability of a KrF laser with an average output power of at least 600 W was investigated. An experimental study was made of the dependences of the rms deviation σ of the output energy on the charging voltage, on the pulse repetition rate, and on the operating time. The value of σ varied from 1.2% to 6.0%, depending on the experimental conditions. For an average power of ∼ 600 W, the deviation σ did not exceed 3.2%. (lasers and amplifiers)

Equatorial 150 km echoes and daytime F region vertical plasma drifts in the Brazilian longitude sector

Directory of Open Access Journals (Sweden)

F. S. Rodrigues

2013-10-01

Full Text Available Previous studies showed that conventional coherent backscatter radar measurements of the Doppler velocity of the so-called 150 km echoes can provide an alternative way of estimating ionospheric vertical plasma drifts during daytime hours (Kudeki and Fawcett, 1993; Chau and Woodman, 2004. Using observations made by a small, low-power 30 MHz coherent backscatter radar located in the equatorial site of São Luís (2.59° S, 44.21° W; −2.35° dip lat, we were able to detect and monitor the occurrence of 150 km echoes in the Brazilian sector. Using these measurements we estimated the local time variation of daytime vertical ionospheric drifts in the eastern American sector. Here, we present a few interesting cases of 150 km-echoes observations made by the São Luís radar and estimates of the diurnal variation of vertical drifts. These cases exemplify the variability of the vertical drifts in the Brazilian sector. Using same-day 150 km-echoes measurements made at the Jicamarca Radio Observatory in Peru, we also demonstrate the variability of the equatorial vertical drifts across the American sector. In addition to first estimates of the absolute vertical plasma drifts in the eastern American (Brazilian sector, we also present observations of abnormal drifts detected by the São Luís radar associated with the 2009 major sudden stratospheric warming event.

Combining task-evoked and spontaneous activity to improve pre-operative brain mapping with fMRI.

Science.gov (United States)

Fox, Michael D; Qian, Tianyi; Madsen, Joseph R; Wang, Danhong; Li, Meiling; Ge, Manling; Zuo, Huan-Cong; Groppe, David M; Mehta, Ashesh D; Hong, Bo; Liu, Hesheng

2016-01-01

Noninvasive localization of brain function is used to understand and treat neurological disease, exemplified by pre-operative fMRI mapping prior to neurosurgical intervention. The principal approach for generating these maps relies on brain responses evoked by a task and, despite known limitations, has dominated clinical practice for over 20years. Recently, pre-operative fMRI mapping based on correlations in spontaneous brain activity has been demonstrated, however this approach has its own limitations and has not seen widespread clinical use. Here we show that spontaneous and task-based mapping can be performed together using the same pre-operative fMRI data, provide complimentary information relevant for functional localization, and can be combined to improve identification of eloquent motor cortex. Accuracy, sensitivity, and specificity of our approach are quantified through comparison with electrical cortical stimulation mapping in eight patients with intractable epilepsy. Broad applicability and reproducibility of our approach are demonstrated through prospective replication in an independent dataset of six patients from a different center. In both cohorts and every individual patient, we see a significant improvement in signal to noise and mapping accuracy independent of threshold, quantified using receiver operating characteristic curves. Collectively, our results suggest that modifying the processing of fMRI data to incorporate both task-based and spontaneous activity significantly improves functional localization in pre-operative patients. Because this method requires no additional scan time or modification to conventional pre-operative data acquisition protocols it could have widespread utility. Copyright © 2015. Published by Elsevier Inc.

33 CFR 150.612 - What footwear is required?

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false What footwear is required? 150... footwear is required? The deepwater port operator must ensure that while personnel are working in an area... footwear that complies with 29 CFR 1910.136, except for when environmental conditions exist that present a...

Progress report and technology status development of an EG and G Berthold LB-150 alpha/beta particulate monitor for use on the East Tennessee Technology Park Toxic Substances Control Act Incinerator

Energy Technology Data Exchange (ETDEWEB)

Shor, J.T.; Singh, S.P.N. [Oak Ridge National Lab., TN (United States). Chemical Technology Div.; Gibson, L.V. Jr. [East Tennessee Technology Park, Oak Ridge, TN (United States). ASO Customer Services Div.

1998-06-01

The purpose of this project was to modify and evaluate a commercially available EG and G Berthold LB-150 alpha-beta radionuclide particulate monitor for the high-temperature and moisture-saturation conditions of the East Tennessee Technology Park (formerly K-25 Site) Toxic Substances Control Act (TSCA) Incinerator stack. The monitor was originally outfitted for operation at gas temperatures of 150 F on the defunct Los Alamos National Laboratory (LANL) controlled air incinerator, and the objective was to widen its operating envelope. A laboratory apparatus was constructed that simulated the effects of water-saturated air at the TSCA Incinerator stack-gas temperatures, 183 F. An instrumented set of heat exchangers was constructed to then condition the gas so that the radionuclide monitor could be operated without condensation. Data were collected under the conditions of the elevated temperatures and humidities and are reported herein, and design considerations of the apparatus are provided. The heat exchangers and humidification equipment performed as designed, the Mylar film held, and the instrument suffered no ill effects. However, for reasons as yet undetermined, the sensitivity of the radionuclide detection diminishes as the gas temperature is elevated, whether the gas is humidified or not. The manufacturer has had no experience with (a) the operation of the monitor under these conditions and (b) any commercial market that might exist for an instrument that operates under these conditions. The monitor was not installed into the radiologically contaminated environment of the TSCA Incinerator stack pending resolution of this technical issue.

Progress report and technology status development of an EG and G Berthold LB-150 alpha/beta particulate monitor for use on the East Tennessee Technology Park Toxic Substances Control Act Incinerator

International Nuclear Information System (INIS)

Shor, J.T.; Singh, S.P.N.; Gibson, L.V. Jr.

1998-06-01

The purpose of this project was to modify and evaluate a commercially available EG and G Berthold LB-150 alpha-beta radionuclide particulate monitor for the high-temperature and moisture-saturation conditions of the East Tennessee Technology Park (formerly K-25 Site) Toxic Substances Control Act (TSCA) Incinerator stack. The monitor was originally outfitted for operation at gas temperatures of 150 F on the defunct Los Alamos National Laboratory (LANL) controlled air incinerator, and the objective was to widen its operating envelope. A laboratory apparatus was constructed that simulated the effects of water-saturated air at the TSCA Incinerator stack-gas temperatures, 183 F. An instrumented set of heat exchangers was constructed to then condition the gas so that the radionuclide monitor could be operated without condensation. Data were collected under the conditions of the elevated temperatures and humidities and are reported herein, and design considerations of the apparatus are provided. The heat exchangers and humidification equipment performed as designed, the Mylar film held, and the instrument suffered no ill effects. However, for reasons as yet undetermined, the sensitivity of the radionuclide detection diminishes as the gas temperature is elevated, whether the gas is humidified or not. The manufacturer has had no experience with (a) the operation of the monitor under these conditions and (b) any commercial market that might exist for an instrument that operates under these conditions. The monitor was not installed into the radiologically contaminated environment of the TSCA Incinerator stack pending resolution of this technical issue

A novel ToF-SIMS operation mode for sub 100 nm lateral resolution: Application and performance

International Nuclear Information System (INIS)

Kubicek, Markus; Holzlechner, Gerald; Opitz, Alexander K.; Larisegger, Silvia; Hutter, Herbert; Fleig, Jürgen

2014-01-01

A novel operation mode for time of flight-secondary ion mass spectrometry (ToF-SIMS) is described for a TOF.SIMS 5 instrument with a Bi-ion gun. It features sub 100 nm lateral resolution, adjustable primary ion currents and the possibility to measure with high lateral resolution as well as high mass resolution. The adjustment and performance of the novel operation mode are described and compared to established ToF-SIMS operation modes. Several examples of application featuring novel scientific results show the capabilities of the operation mode in terms of lateral resolution, accuracy of isotope analysis of oxygen, and combination of high lateral and mass resolution. The relationship between high lateral resolution and operation of SIMS in static mode is discussed.

Performance of a 150-MW S-band klystron

International Nuclear Information System (INIS)

Sprehn, D.; Phillips, R.M.; Caryotakis, G.

1994-09-01

As part of an international collaboration, the Stanford Linear Accelerator Center (SLAC) klystron group has designed, fabricated, and tested a 60-Hz, 3-μs, 150-MW S-band klystron built for Deutsches Elektronen Synchrotron (DESY). A test diode with a 535-kV, 700-A electron beam was constructed to verify the gun operation. The first klystron was built and successfully met design specifications. The 375-MW electron beam represents a new record for SLAC accelerator klystrons in terms of voltage, current, energy, and ruggedness of design. The rf output power is a 150% increase over the S-band tubes currently used in the two-mile-long linear accelerator at SLAC. This paper discusses design issues and experimental results of the diode and klystron

Potential Hazards Relating to Pyrolysis of c-C4F8O, n-C4F10 and c-C4F8 in selected gaseous diffusion plant operations

International Nuclear Information System (INIS)

Trowbridge, L.D.

2000-01-01

As part of a program intended to replace the present evaporative coolant at the gaseous diffusion plants (GDPs) with a non-ozone-depleting alternate, a series of investigations of the suitability of candidate substitutes is under way. This report summarizes studies directed at estimating the chemical and thermal stability of three candidate coolants, c-C 4 F 8 O, n-C 4 F 10 and c-C 4 4F 8 , in a few specific environments to be found in gaseous diffusion plant operations

37 CFR 150.4 - Evaluation.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Evaluation. 150.4 Section 150...(a)(2) § 150.4 Evaluation. (a) Upon submission of a request by a foreign government for the issuance... Director to initiate independently an evaluation pursuant to § 150.2(a) of this part, a notice will be...

CRITICAL ASSUMPTIONS IN THE F-TANK FARM CLOSURE OPERATIONAL DOCUMENTATION REGARDING WASTE TANK INTERNAL CONFIGURATIONS

Energy Technology Data Exchange (ETDEWEB)

Hommel, S.; Fountain, D.

2012-03-28

The intent of this document is to provide clarification of critical assumptions regarding the internal configurations of liquid waste tanks at operational closure, with respect to F-Tank Farm (FTF) closure documentation. For the purposes of this document, FTF closure documentation includes: (1) Performance Assessment for the F-Tank Farm at the Savannah River Site (hereafter referred to as the FTF PA) (SRS-REG-2007-00002), (2) Basis for Section 3116 Determination for Closure of F-Tank Farm at the Savannah River Site (DOE/SRS-WD-2012-001), (3) Tier 1 Closure Plan for the F-Area Waste Tank Systems at the Savannah River Site (SRR-CWDA-2010-00147), (4) F-Tank Farm Tanks 18 and 19 DOE Manual 435.1-1 Tier 2 Closure Plan Savannah River Site (SRR-CWDA-2011-00015), (5) Industrial Wastewater Closure Module for the Liquid Waste Tanks 18 and 19 (SRRCWDA-2010-00003), and (6) Tank 18/Tank 19 Special Analysis for the Performance Assessment for the F-Tank Farm at the Savannah River Site (hereafter referred to as the Tank 18/Tank 19 Special Analysis) (SRR-CWDA-2010-00124). Note that the first three FTF closure documents listed apply to the entire FTF, whereas the last three FTF closure documents listed are specific to Tanks 18 and 19. These two waste tanks are expected to be the first two tanks to be grouted and operationally closed under the current suite of FTF closure documents and many of the assumptions and approaches that apply to these two tanks are also applicable to the other FTF waste tanks and operational closure processes.

The 150 kV cp microfocus X-ray unit

NARCIS (Netherlands)

Fontijn, L.A.

1979-01-01

Development of microfocus X-ray technique is defined. Advantages on other methods, principle of operation and the material comprising an intense electron source imaged on an X-ray target by means of a double magnetic lense system, are described. Resolution value at 150 kV is the imaging of a 0.1 mm

33 CFR 150.531 - How many fire pumps must be kept ready for use at all times?

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false How many fire pumps must be kept ready for use at all times? 150.531 Section 150.531 Navigation and Navigable Waters COAST GUARD... Specialty Equipment Miscellaneous Operations § 150.531 How many fire pumps must be kept ready for use at all...

A novel ToF-SIMS operation mode for sub 100 nm lateral resolution: Application and performance.

Science.gov (United States)

Kubicek, Markus; Holzlechner, Gerald; Opitz, Alexander K; Larisegger, Silvia; Hutter, Herbert; Fleig, Jürgen

2014-01-15

A novel operation mode for time of flight-secondary ion mass spectrometry (ToF-SIMS) is described for a TOF.SIMS 5 instrument with a Bi-ion gun. It features sub 100 nm lateral resolution, adjustable primary ion currents and the possibility to measure with high lateral resolution as well as high mass resolution. The adjustment and performance of the novel operation mode are described and compared to established ToF-SIMS operation modes. Several examples of application featuring novel scientific results show the capabilities of the operation mode in terms of lateral resolution, accuracy of isotope analysis of oxygen, and combination of high lateral and mass resolution. The relationship between high lateral resolution and operation of SIMS in static mode is discussed.

Thermoluminescent properties of LiF:NaF multilayers thin films

International Nuclear Information System (INIS)

Mauricio, Claudia Lucia P.; Mauricio, Marcos H.P.; Nunes, Raul A.

1996-01-01

LiF and NaF and LiF:NaF multilayer films were grown by the assisted physical deposition method of beam evaporation. All films were grown by the assisted physical deposition method of e-beam evaporation. All films were made with a deposition rate of 10 A/s on aluminium and stainless steel substrates. Both substrates were kept at room temperature, 150 deg C and 300 deg C. The films were irradiated with 10 Gy in a 60 Co source. The thermoluminescence (TL) glow curves are similar for both substrates, with only a small dislocation in temperature of about 10 deg C. This dislocation in temperature are supposed to be related with its different thermal conductivity. The TL glow curves of films grown on aluminium substrates are more intense. TL of LiF films are similar of the TL of LiF crystals. The TL glow curves of multilayer LiF:NaF films can not be explained as a simple superposition of the glow curves of individual LiF and NaF layers. Thin layers of NaF seems not change very much the glow peaks structure of LiF films. (author)

7 CFR 65.150 - Goat.

Science.gov (United States)

2010-01-01

..., PORK, LAMB, CHICKEN, GOAT MEAT, PERISHABLE AGRICULTURAL COMMODITIES, MACADAMIA NUTS, PECANS, PEANUTS, AND GINSENG General Provisions Definitions § 65.150 Goat. Goat means meat produced from goats. ... 7 Agriculture 3 2010-01-01 2010-01-01 false Goat. 65.150 Section 65.150 Agriculture Regulations of...

Streamer free operation of a 2 mm gap resistive plate chamber with $C_{2}F_{5}H$

CERN Document Server

Cerron-Zeballos, E; Hatzifotiadou, D; Lamas-Valverde, J; Williams, M C S; Zichichi, A

1999-01-01

It is necessary to operate the resistive plate chamber (RPC) in avalanche mode to obtain high efficiency at elevated particle fluxes. We examine this mode of operation with a 2 mm gap RPC using gas mixtures containing C/sub 2/F/sub 4/H/sub 2/ and C/sub 2/F/sub 5/H. In order to explain the data we propose that the avalanche growth is strongly limited by space charge effects. (10 refs).

7 CFR 58.150 - Containers.

Science.gov (United States)

2010-01-01

... 7 Agriculture 3 2010-01-01 2010-01-01 false Containers. 58.150 Section 58.150 Agriculture... Identification § 58.150 Containers. (a) The size, style, and type of packaging used for dairy products shall be commercially acceptable containers and packaging materials which will satisfactorily cover and protect the...

45 CFR 150.413 - Settlement.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Settlement. 150.413 Section 150.413 Public Welfare DEPARTMENT OF HEALTH AND HUMAN SERVICES REQUIREMENTS RELATING TO HEALTH CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS Administrative Hearings § 150.413 Settlement. CMS has exclusive...

10 CFR 60.150 - Scope.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Scope. 60.150 Section 60.150 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) DISPOSAL OF HIGH-LEVEL RADIOACTIVE WASTES IN GEOLOGIC REPOSITORIES Quality Assurance § 60.150 Scope. As used in this part, quality assurance comprises all those planned and systematic...

β- decay of 150Ce to odd-odd 150Pr

International Nuclear Information System (INIS)

Kojima, Yasuaki; Shibata, Michihiro; Kosuga, Kazuto; Shima, Yosuke; Taniguchi, Akihiro; Hayashi, Hiroaki

2015-01-01

The β - decay of 150 Ce having a half-life of 6.05(7) s produced by the thermal-neutron-induced fission of 235 U has been studied using the on-line isotope separator at the Kyoto University Research Reactor. A decay scheme containing 18 excited levels and 55 γ-rays was constructed from γ-ray singles and γ-γ coincidence measurements. Of these, 9 levels and 37 γ-rays were newly placed. The dominant β-feeding observed at the 110 keV level of 150 Pr was found to be an allowed unhindered spin-flip transition. On the basis of the systematics of the neighboring nuclides, the Gallagher-Moszkowski coupling rules, and the selection rules for the β-decay of deformed nuclei, the Nilsson configurations of the ground and 110 keV states in 150 Pr were newly proposed to be π5/2 + [413]-ν3/2 - [521] and π5/2 - [532]-ν3/2 - [532], respectively. (author)

21 CFR 812.150 - Reports.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Reports. 812.150 Section 812.150 Food and Drugs... INVESTIGATIONAL DEVICE EXEMPTIONS Records and Reports § 812.150 Reports. (a) Investigator reports. An investigator shall prepare and submit the following complete, accurate, and timely reports: (1) Unanticipated adverse...

45 CFR 150.435 - Discovery.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Discovery. 150.435 Section 150.435 Public Welfare... AND INDIVIDUAL INSURANCE MARKETS Administrative Hearings § 150.435 Discovery. (a) The parties must identify any need for discovery from the opposing party as soon as possible, but no later than the time for...

Diagnostic utility of PET/CT with {sup 18}F-DOPA and {sup 18}F-FDG in persistent or recurrent medullary thyroid carcinoma: the importance of calcitonin and carcinoembryonic antigen cutoff

Energy Technology Data Exchange (ETDEWEB)

Romero-Lluch, Ana Reyes; Guerrero-Vazquez, Raquel; Martinez-Ortega, Antonio Jesus; Navarro-Gonzalez, Elena [Hospital Universitario Virgen del Rocio, Unidad de Gestion Clinica de Endocrinologia y Nutricion, Seville (Spain); Cuenca-Cuenca, Juan Ignacio; Tirado-Hospital, Juan Luis; Borrego-Dorado, Isabel [Hospital Universitario Virgen del Rocio, Unidad de Medicina Nuclear, Seville (Spain)

2017-11-15

This study sought to evaluate and compare the utility of 18-F-fluorodihydroxyphenylalanine ({sup 18}F-DOPA) and 18-F-fluorodeoxyglucose ({sup 18}F-FDG) positron emission tomography/computed tomography (PET/CT) for identification of lesions in patients with recurrent medullary thyroid carcinoma (MTC). In addition, we analyzed the correlation between the calcitonin (Ct), carcinoembryonic antigen (CEA) levels, each doubling time (DT), and PET positivity. We evaluated the reliability of the 150 pg/mL Ct cutoff set by the American Thyroid Association guidelines for further imaging (including {sup 18}F-DOPA PET/CT). We prospectively recruited 18 patients with recurrent MTC, identified by elevation of Ct or CEA. Each patient underwent a {sup 18}F-FDG PET/CT and a {sup 18}F-DOPA PET/CT. Abnormal uptakes were detected with {sup 18}F-DOPA (n=12) and {sup 18}F-FDG (n=9), (sensitivity of 66.7% vs. 50%; p<0.01). Twenty-eight lesions were detected with {sup 18}F-DOPA vs. 16 lesions with {sup 18}F-FDG (1.56±1.5 vs. 0.89±1.18 lesions per patient; p=0.01). None of our patients showed additional lesions with {sup 18}F-FDG in comparison to {sup 18}F-DOPA. Patient-based detection rate increased significantly with Ct levels ≥150 pg/mL vs. Ct<150 pg/mL for both {sup 18}F-DOPA (sensitivity 90.9% vs. 28.6%; p=0.013) and {sup 18}F-FDG PET/CT (sensitivity 72.7% vs. 14.3%; p=0.025). Using a CEA cutoff of ≥5 ng/mL, detection rates of {sup 18}F-DOPA and {sup 18}F-FDG PET/CT were 81.1% and 72.7%, respectively. No correlation between Ct-DT or CEA-DT and PET positivity was found. Histological confirmation was obtained in eight patients. {sup 18}F-DOPA PET/CT appears to be superior to {sup 18}F-FDG PET/CT in detecting and locating lesions in patients with recurrent MTC. This technique tends to be especially useful in patients with negative results in other imaging modalities and Ct≥150 pg/mL or CEA≥5 ng/mL. (orig.)

Design study of shaft face seal with self-acting lift augmentation. 5: Performance in simulated gas turbine engine operation

Science.gov (United States)

Ludwig, L. P.; Johnson, R. L.

1971-01-01

The feasibility and the noncontact operation of the self-acting seal was demonstrated over a range of simulated gas turbine engine conditions from 200 to 500 ft/sec sliding speed. Sealed pressure differentials were 50 to 300 psi and sealed temperatures were 150 to 1200 F. Low leakage (about 1/10 that of conventional labyrinth seals) was exhibited in two endurance runs (200 and 338 hr) at 400 ft/sec, 200 psi and 1000 F (gas temperature). For these endurance runs, the self-acting pad wear was less than 3.8 micrometers (0.00015 in.); this low wear was attributed to the noncontact operation of the primary seal. Operating problems identified were fretting wear of the secondary seal and erosion of the primary seal by hard particles.

33 CFR 150.515 - What are the requirements for weight testing of newly installed or relocated craft?

Science.gov (United States)

2010-07-01

... weight testing of newly installed or relocated craft? 150.515 Section 150.515 Navigation and Navigable... testing of newly installed or relocated craft? (a) The operator must perform installation weight testing... (a) of this section, when survival crafts are relocated to another deepwater port. ...

Process pump operating problems and equipment failures, F-Canyon Reprocessing Facility, Savannah River Plant

International Nuclear Information System (INIS)

Durant, W.S.; Starks, J.B.; Galloway, W.D.

1987-02-01

A compilation of operating problems and equipment failures associated with the process pumps in the Savannah River Plant F-Canyon Fuel Reprocessing Facility is presented. These data have been collected over the 30-year operation of the facility. An analysis of the failure rates of the pumps is also presented. A brief description of the pumps and the data bank from which the information was sorted is also included

ORNL 150 keV neutral beam test facility

International Nuclear Information System (INIS)

Gardner, W.L.; Kim, J.; Menon, M.M.; Schilling, G.

1977-01-01

The 150 keV neutral beam test facility provides for the testing and development of neutral beam injectors and beam systems of the class that will be needed for the Tokamak Fusion Test Reactor (TFTR) and The Next Step (TNS). The test facility can simulate a complete beam line injection system and can provide a wide range of experimental operating conditions. Herein is offered a general description of the facility's capabilities and a discussion of present system performance

A-150 plastic radiometric calorimeter for charged particles and other radiations

International Nuclear Information System (INIS)

McDonald, J.C.; Domen, S.R.

1986-01-01

A local absorbed dose calorimeter with certain novel features has been designed and constructed of A-150 tissue-equivalent (TE) plastic. The radiation absorption properties of this material and the relative absence of core impurities make the calorimeter suitable for use in a wide variety of radiation beams. The low thermal diffusivity of A-150 plastic led to the development of a unique spiral electrical calibration heater that has a mass of only 0.1% that of the core. The calorimeter can be calibrated in the quasiadiabatic or the heat-loss-compensated mode to test for possible effects caused by temperature gradients. The details of construction and operation are described. (orig.)

Synthesis of [18F]-(S)-fluoxetine: a selective serotonine uptake inhibitor

International Nuclear Information System (INIS)

Hammadi, A.; Crouzel, C.

1993-01-01

The (S)-N-methyl-γ-[4-(trifluoromethyl)phenoxy] benzenepropanamine, an antidepressant with potential applications in the treatment of other illnesses was labelled with fluorine-18 for Positron Emission Tomography studies. The synthesis was accomplished from the [ 18 F]-4-chlorobenzotrifluoride where [ 18 F]-label was introduced via a nucleophilic aliphatic substitution reaction. [ 18 F]-(S)-Fluoxetine was obtained with a radiochemical yield of 9-10% (decay corrected) and a specific radioactivity of 100-150 mCi/μmol (3.70-5.55 GBq/μmol) in a total synthesis time of 150 min. A facile isotopic exchange reaction was demonstrated; it is expected to reduce the specific activity of the final [ 18 F]-product. The experimental parameters play an important role, which is discussed. (Author)

Karyotype analysis in Machaerium lunatum (Linn. f.) Ducke ...

African Journals Online (AJOL)

ADOWIE PERE

2017-12-11

Dec 11, 2017 ... Ducke (syn. Drepanocarpus lunatus (Linn. f.) G.F.W. Mey) belongs to the family Fabaceae-Papilionaceae. (Hutchinson and Dalziel 1954). It has about 130 species distributed from Mexico to Argentina which are difficult to delimit taxonomically (Rudd 1987) and 150 species distributed from Mexico to South.

7 CFR 1726.150 - Headquarters buildings.

Science.gov (United States)

2010-01-01

... 7 Agriculture 11 2010-01-01 2010-01-01 false Headquarters buildings. 1726.150 Section 1726.150... AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Buildings § 1726.150 Headquarters buildings. This section includes headquarters buildings such as warehouses and equipment service type buildings...

33 CFR 150.606 - After learning of a possible violation, what does the Officer in Charge of Marine Inspection do?

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false After learning of a possible violation, what does the Officer in Charge of Marine Inspection do? 150.606 Section 150.606 Navigation and...: OPERATIONS Workplace Safety and Health Safety and Health (general) § 150.606 After learning of a possible...

21 CFR 211.150 - Distribution procedures.

Science.gov (United States)

2010-04-01

...: GENERAL CURRENT GOOD MANUFACTURING PRACTICE FOR FINISHED PHARMACEUTICALS Holding and Distribution § 211.150 Distribution procedures. Written procedures shall be established, and followed, describing the... 21 Food and Drugs 4 2010-04-01 2010-04-01 false Distribution procedures. 211.150 Section 211.150...

45 CFR 150.217 - Preliminary determination.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Preliminary determination. 150.217 Section 150.217... Are Failing To Substantially Enforce HIPAA Requirements § 150.217 Preliminary determination. If, at... designees). (b) Notifies the State of CMS's preliminary determination that the State has failed to...

45 CFR 150.219 - Final determination.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Final determination. 150.219 Section 150.219... Are Failing To Substantially Enforce HIPAA Requirements § 150.219 Final determination. If, after... the State a written notice of its final determination. The notice includes the following: (a...

The improved syntheses of 5-substituted 2'-[18F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([18F]FAU, [18F]FEAU, [18F]FFAU, [18F]FCAU, [18F]FBAU and [18F]FIAU) using a multistep one-pot strategy

International Nuclear Information System (INIS)

Cai Hancheng; Li Zibo; Conti, Peter S.

2011-01-01

Introduction: We and others have previously reported a four-step radiosynthesis of a series of 2'-deoxy-2'-[ 18 F]fluoro-5-substituted-1-β-D-arabinofuranosyluracil derivatives including [ 18 F]FAU, [ 18 F]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU as thymidine derivatives for tumor proliferation and/or reporter gene expression imaging with positron emission tomography (PET). Although the radiosynthesis has been proven to be reproducible and efficient, this complicated multistep reaction is difficult to incorporate into an automated cGMP-compliant radiosynthesis module for routine production. Recently, we have developed a simple and efficient one-pot method for routine production of [ 18 F]FMAU. In this study, we studied the feasibility of radiosynthesizing [ 18 F]FAU, [ 18 F]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU using this newly developed method. Methods: Similar to the radiosynthesis of [ 18 F]FMAU, 5-substituted 2'-[ 18 F]fluoro-2'-deoxy-arabinofuranosyluracil derivatives ([ 18 F]FAU, [ 18 F]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU) were synthesized in one-pot radiosynthesis module in the presence of Friedel-Crafts catalyst TMSOTf and HMDS. Results: This one-pot radiosynthesis method could be used to produce [ 18 F]FAU, [ 18 F]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU. The overall radiochemical yields of these tracers varied from 4.1%±0.8% to 10.1%±1.9% (decay-corrected, n=4). The overall reaction time was reduced from 210 min to 150 min from the end of bombardment, and the radiochemical purity was >99%. Conclusions: The improved radiosyntheses of [ 18 F]FAU, [ 18 F]FEAU, [ 18 F]FFAU, [ 18 F]FCAU, [ 18 F]FBAU and [ 18 F]FIAU have been achieved with reasonable yields and high purity using a multistep one-pot method. The synthetic time has been reduced, and the reaction procedures have been significantly simplified. The success of this approach may make PET tracers [ 18 F]FAU, [ 18 F

Study of gamma-ray induced variability on F1M1-F3M3 distant tomato hybrids

International Nuclear Information System (INIS)

Siromeatnicov, Iulia; Cotenco, Eugenia; Ciobanu, Renata

2013-01-01

The outcome of the evaluation of the gamma radiation's action, the growth and development tomato plant has shown that the coefficient of variation of plant height character is on the rise with increasing doses of gamma radiation. The hybrid combination F 1 M 1 (L.hpriz.1998) irradiated with dose 150 Gy variant presented superior value a towards scrutiny for plant height of the characters, number of flowers and fruits per bunch, number of fruits per plant and fruit mass of. The character F 2 M 2 generation plant height registered diminished value compared to F 1 M 1 generation. The highest value was recorded at the hybrid combination F 2 M 2 L.hpriz.1998 200 Gy treated dose. The evaluation research has highlighted that at the doses 100 Gy, 150 Gy, 200 Gy, have confirmed an increase in characters of reproductive system: the number of flowers and fruits per bunch, number of fruits per plant, fruit mass and reduction of the characters waist and height of placing of the first inflorescences plant. Similar aspects with some differences as low as hybrid combination Lhpi1998 in relation to the radiation doses used under study were confirmed in the case F 3 M 3 . (authors)

41 CFR 105-1.150 - Citation.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Citation. 105-1.150 Section 105-1.150 Public Contracts and Property Management Federal Property Management Regulations System (Continued) GENERAL SERVICES ADMINISTRATION 1-INTRODUCTION 1.1-Regulations System § 105-1.150 Citation. (a...

29 CFR 1926.150 - Fire protection.

Science.gov (United States)

2010-07-01

... 29 Labor 8 2010-07-01 2010-07-01 false Fire protection. 1926.150 Section 1926.150 Labor... (CONTINUED) SAFETY AND HEALTH REGULATIONS FOR CONSTRUCTION Fire Protection and Prevention § 1926.150 Fire protection. (a) General requirements. (1) The employer shall be responsible for the development of a fire...

Operational experience with the Fermilab 150 GeV injection kicker

International Nuclear Information System (INIS)

Trendler, R.C.

1985-01-01

The Fermilab E17 injection kicker has been in operation for more than 12000 filament hours and has logged almost 350,000 pulses since commissioning without major failure. The kicker system uses EEV 1193B and 1193C double-ended thyratrons in the MAIN, CLIP and DUMP configuration. In typical operation, the pulser produces 4800 A, 20 μs pulses at a charging voltage of 60kV and is capable of operating at a 80kV charging voltage. Any failure of the injection process can cause the Tevatron cryogenic magnets to quench. This includes any misfires of the injection kicker. Considerable effort was made to maximize reliability and provide interlocks to limit the problems that could happen from injection kicker misfires. The operating experience and reliability of the EEV thyratron will be discussed. Also, the use of the fiber optics, unique charging power supplies, and unusual digital interlocks and the role they play in improved reliability will be discussed

Useful effectiveness of plastic pipes for gas pipelines operating at low pressure

Energy Technology Data Exchange (ETDEWEB)

Zayutsev, K I

1976-06-01

Because a significant portion of the feeder lines in the Soviet union operate at relatively low pressures up to 75 to 150 psi, it is economically feasible to replace the conventional pipeline material (steel) with plastic. Cost savings result from lower material costs and ease of laying plastic pipe. Because of stiffness and corrosion requirements, the steel pipe used for these low-pressure pipelines is much thicker than needed to withstand the pressure used. Data are tabulated on the comparative costs and manpower requirements for the construction of 1 km of steel, polyvinyl chloride, and polyethylene gas pipelines ranging in diameter from 3 to 14 in. Generally, the plastic pipelines required 15 to 30% less man-days and were 20 to 35% lower in cost to build. The plastic pipelines can operate at 150 to 175 psi pressure and at temperatures up to 100 to 140/sup 0/F. In research conducted at VNIIST (All-Union Research Institute for the Construction of Trunk Pipelines) on plastic pipelines, a 2.5-mile test section has been operating successfully for 2 years, and new techniques and equipment for joining plastic pipe up to 25-in. diameter are being developed.

150 Passenger Commercial Aircraft

Science.gov (United States)

Bucovsky, Adrian; Romli, Fairuz I.; Rupp, Jessica

2002-01-01

It has been projected that the need for a short-range mid-sized, aircraft is increasing. The future strategy to decrease long-haul flights will increase the demand for short-haul flights. Since passengers prefer to meet their destinations quickly, airlines will increase the frequency of flights, which will reduce the passenger load on the aircraft. If a point-to-point flight is not possible, passengers will prefer only a one-stop short connecting flight to their final destination. A 150-passenger aircraft is an ideal vehicle for these situations. It is mid-sized aircraft and has a range of 3000 nautical miles. This type of aircraft would market U.S. domestic flights or inter-European flight routes. The objective of the design of the 150-passenger aircraft is to minimize fuel consumption. The configuration of the aircraft must be optimized. This aircraft must meet CO2 and NOx emissions standards with minimal acquisition price and operating costs. This report contains all the work that has been performed for the completion of the design of a 150 passenger commercial aircraft. The methodology used is the Technology Identification, Evaluation, and Selection (TIES) developed at Georgia Tech Aerospace Systems Design laboratory (ASDL). This is an eight-step conceptual design process to evaluate the probability of meeting the design constraints. This methodology also allows for the evaluation of new technologies to be implemented into the design. The TIES process begins with defining the problem with a need established and a market targeted. With the customer requirements set and the target values established, a baseline concept is created. Next, the design space is explored to determine the feasibility and viability of the baseline aircraft configuration. If the design is neither feasible nor viable, new technologies can be implemented to open up the feasible design space and allow for a plausible solution. After the new technologies are identified, they must be evaluated

42 CFR 423.150 - Scope.

Science.gov (United States)

2010-10-01

... 42 Public Health 3 2010-10-01 2010-10-01 false Scope. 423.150 Section 423.150 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICARE PROGRAM VOLUNTARY MEDICARE PRESCRIPTION DRUG BENEFIT Cost Control and Quality Improvement Requirements...

26 CFR 1.50B-4 - Partnerships.

Science.gov (United States)

2010-04-01

... § 1.50A-3, or if the partnership fails to pay comparable wages and such failure is subject to the... 26 Internal Revenue 1 2010-04-01 2010-04-01 true Partnerships. 1.50B-4 Section 1.50B-4 Internal... Credit for Expenses of Work Incentive Programs § 1.50B-4 Partnerships. (a) General rule—(1) In general...

Advanced operation strategy for feed-and-bleed operation in an OPR1000

International Nuclear Information System (INIS)

Kim, Bo Gyung; Yoon, Ho Joon; Kim, Jaewhan; Kang, Hyun Gook

2016-01-01

Highlights: • Advanced operating strategy covers all necessary conditions for F&B operation. • Advanced operating strategy identifies the urgency of F&B operation. • An advanced operating strategy for F&B operation is developed using a decision tree. • Human error probability is re-estimated based on a thermohydraulic analysis and K-HRA method. • An advanced operation strategy provides indications under various plant situations. - Abstract: When the secondary side is unavailable in a pressurized water reactor (PWR), heat from the core will accumulate in the primary side causing core damage. In this situation a heat removal mechanism called feed-and-bleed operation (F&B operation) must be used, which is a process of directly cooling the primary reactor cooling system (RCS). However, conventional operation strategy in emergency operating procedures (EOPs) does not cover all possible conditions to initiate F&B operation. If the EOP informs on the urgency of F&B operation, operators will be able to more clearly make decisions regarding F&B operation initiation. In order to cover all possible scenarios for F&B operation and systematically inform its urgency, an advanced operating strategy using a decision tree is developed in this study. The plant condition can be classified according to failure of secondary side, RCS pressure condition, injectable inventory to RCS, and remaining core inventory. RCS pressure, core level, and RCS temperature are representative indicators which provide information regarding the initiation of F&B operation. Indicators can be selected based on their detectability and quantification, and a decision tree is developed according to combinations of indicators. To estimate the effects of the advanced operation strategy, human error probability (HEP) of F&B operation is re-estimated based on a thermohydraulic analysis. The available time for operators to initiate F&B operation is also re-estimated to obtain more realistic data. This

High-spin states in the transitional odd-odd nuclei 150Eu and 152Tb

International Nuclear Information System (INIS)

Barneoud, D.; Foin, C.; Pinston, J.A.; Monnand, E.

1983-06-01

The ( 7 Li, 5n) and ( 11 B, 5n) reactions have been used to study the high-spin states in the two odd-odd nuclei 150 Eu and 152 Tb. Three decoupled bands have been evidenced in each nucleus belonging to the same configurations [f 7/2]sub(n) [h 11/2]sub(p), [h 9/2]sub(n) [h 11/2 ]sub(p) and [i 13/2]sub(n) [h 11/2]sub(p). The latter one is well developped and improves our knowledge of this system between the spherical and deformed region. The analysis of the collective moment of inertia and transition ratios strongly suggests an increase of the deformation when the rotational frequency increases in these two transitional nuclei 150 Eu and 152 Tb

Reedsport PB150 Deployment and Ocean Test Project

Energy Technology Data Exchange (ETDEWEB)

Hart, Phil [Ocean Power Technologies Inc., Pennington, NJ (United States)

2016-06-03

As the first utility scale wave power project in the US, the Wave Power Demonstration Project at Reedsport (OR) was planned to consist of 10 PowerBuoys (Phase II)1, located 2.5 miles off the coast. U.S. Department of Energy (DOE) funding under a prior DOE Grant (DE-FG36-08GO88017) along with funding from PNGC Power, an Oregon-based electric power cooperative, was utilized for the design completion, fabrication, assembly and factory testing of the first PowerBuoy for the Reedsport project. The design and fabrication of the first PowerBuoy and factory testing of the power take-off subsystem were completed, and the power take-off subsystem was successfully integrated into the spar at the fabricator’s facility in Oregon. The objectives of this follow-on grant were: advance PB150B design from TRL 5/6 to TRL 7/8; deploy a single PB150 and operate autonomously for 2 years; establish O&M costs; collect environmental information; and establish manufacturing methodologies.

21 CFR 820.150 - Storage.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Storage. 820.150 Section 820.150 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED) MEDICAL DEVICES... product to prevent mixups, damage, deterioration, contamination, or other adverse effects pending use or...

Synthesis of [[sup 18]F]-(S)-fluoxetine: a selective serotonine uptake inhibitor

Energy Technology Data Exchange (ETDEWEB)

Hammadi, A.; Crouzel, C. (CEA, 91 - Orsay (France). Service Hospitalier Frederic Joliot)

1993-01-01

The (S)-N-methyl-[gamma]-[4-(trifluoromethyl)phenoxy] benzenepropanamine, an antidepressant with potential applications in the treatment of other illnesses was labelled with fluorine-18 for Positron Emission Tomography studies. The synthesis was accomplished from the [[sup 18]F]-4-chlorobenzotrifluoride where [[sup 18]F]-label was introduced via a nucleophilic aliphatic substitution reaction. [[sup 18]F]-(S)-Fluoxetine was obtained with a radiochemical yield of 9-10% (decay corrected) and a specific radioactivity of 100-150 mCi/[mu]mol (3.70-5.55 GBq/[mu]mol) in a total synthesis time of 150 min. A facile isotopic exchange reaction was demonstrated; it is expected to reduce the specific activity of the final [[sup 18]F]-product. The experimental parameters play an important role, which is discussed. (Author).

37 CFR 41.150 - Discovery.

Science.gov (United States)

2010-07-01

... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Discovery. 41.150 Section 41... COMMERCE PRACTICE BEFORE THE BOARD OF PATENT APPEALS AND INTERFERENCES Contested Cases § 41.150 Discovery. (a) Limited discovery. A party is not entitled to discovery except as authorized in this subpart. The...

A Study on the Operator Decision Support for Feed-and-Bleed Operation

International Nuclear Information System (INIS)

Kim, Bo Gyung; Kim, Sang Ho; Kang, Hyun Gook; Yoon, Ho Joon

2014-01-01

In the case of a combined accident that includes a failure of the secondary cooling system, it is difficult for operators to recognize the necessity of an feed and bleed (F and B) operation because a lot of parameters and alarms should be checked before a decision, and operators may spend a considerable amount of time arriving at the entry for a proper emergency operating procedure that contains the procedure for an F and B operation. Therefore, a clear identification of the success boundary of an F and B operation would help operators in their decision-making when a combined accident that includes a secondary cooling system failure occurs. This study will provide a useful guideline for the initiation of an F and B operation for operators. Cooling the RCS after a scram is one of the most important safety functions for preventing core damage. To support the operator in decision making whether to initiate the F and B operation, plant conditions requiring the initiation of an F and B operation were identified. Plant conditions are affected by the steam generator inventory, RCS inventory, core inventory, and safety injection availability. The combination of accident types, component availabilities, and the initiation time of an F and B operation affect the success of the F and B operation. Operators need clear information about the RCS condition when the steam generators, the RCS's main residual heat removal mechanism, become unavailable. When this happens, the initiation of an F and B operation becomes necessary. As the number of the state increases, the necessity of an F and B operation increases. Especially, the operator should initiate an F and B operation when the RCS condition enters State 3 for Type 1 incidents or State 3-2 for Type 2 incidents. The results of this study may be useful in providing information regarding the necessity and effects of an F and B operation in a quantitative manner. In particular, in the case of a combined accident including a

Radiation exposure to surgical staff during F-18-FDG-guided cancer surgery

International Nuclear Information System (INIS)

Andersen, P.A.; Hesse, B.; Chakera, A.H.; Schmidt, G.; Klausen, T.L.; Binderup, T.; Grossjohann, H.S.; Friis, E.; Hansen, C.P.; Kjaer, A.

2008-01-01

High-energy gamma probes have recently become commercially available, developed for 18 F-FDG probe-guided surgery. The radiation received by the staff in the operating room might limit the use of it, but has never been determined. We therefore wanted to measure the absorbed staff doses at operations where patients had received a preoperative injection of 18 F-FDG. Thirty-four patients with different cancers (breast cancer, melanoma, gastrointestinal cancers, respectively) were operated. At every operation the surgeon was monitored with a TLD tablet on his finger of the operating hand and a TLD tablet on the abdomen. The surgeon and anaesthesiologist were also monitored using electronic dosimeters placed in the trousers lining at 25 operations. The dose rate to the surgeon's abdominal wall varied between 7.5-13.2 μSv/h, depending on tumour location. The doses to the anaesthesiologists and the finger doses to the surgeon were much lower. About 350-400 MBq, i.e. ca. eight times higher activities than those used in the present study are supposed to be necessary for guiding surgery. It can be calculated from the body doses measured that a surgeon can perform between 150-260 h of surgery without exceeding permissible limits for professional workers. The radiation load to the operating staff will generally be so small that it does not present any limitation for FDG-guided surgery. However, it is recommended to monitor the surgical staff considering that the surgeon may be exposed to other radiation sources, and since the staff often includes women of child-bearing age. (orig.)

A Double Inverted F-Shape Patch Antenna for Dual-Band Operation

Directory of Open Access Journals (Sweden)

M. M. Islam

2014-01-01

Full Text Available A double inverted F-shape patch antenna is presented for dual-band operation. The proposed antenna is comprised of circular and rectangular slots on a printed circuit board of 40 mm × 40 mm × 1.6 mm with a 50 Ω microstrip transmission line. Commercially available high frequency structural simulator (HFSS based on the finite element method (FEM has been adopted in this investigation. It has a measured impedance bandwidths (2 : 1 VSWR of 18.53% on the lower band and 7.8% on the upper band, respectively. It has achieved stable radiation efficiencies of 79.76% and 80.36% with average gains of 7.82 dBi and 5.66 dBi in the operating frequency bands. Moreover, numerical simulations have been indicated as an important uniformity with measured results.

Generating an AC amplitude magnetic flux density value up to 150 μT at a frequency up to 100 kHz

Science.gov (United States)

Ulvr, Michal; Polonský, Jakub

2017-05-01

AC magnetic field analyzers with a triaxial coil probe are widely used by health and safety professionals, in manufacturing, and in service industries. For traceable calibration of these analyzers, it is important to be able to generate a stable, homogeneous reference AC magnetic flux density (MFD). In this paper, the generating of AC amplitude MFD value of 150 μT by single-layer Helmholtz type solenoid, described in previous work, was expanded up to a frequency of 100 kHz using the effect of serial resonance. A programmable capacitor array has been developed with a range of adjustable values from 50 pF to 51225 pF. In addition, the multi-layer search coil with a nominal area turns value of 1.3m2, used for adjusting AC MFD in the solenoid, has been modified by a transimpedance amplifier for use in a wider frequency range than up to 3 kHz. The possibility of using the programmable capacitor array up to 150 kHz has also been tested. An AC amplitude MFD value of 150 μT can be generated with expanded uncertainty better than 0.6% up to 100 kHz.

Impact of JAK2V617F Mutation Burden on Disease Phenotype in Chinese Patients with JAK2V617F-positive Polycythemia Vera (PV) and Essential thrombocythemia (ET).

Science.gov (United States)

Zhao, Shixiang; Zhang, Xiang; Xu, Yang; Feng, Yufeng; Sheng, Wenhong; Cen, Jiannong; Wu, Depei; Han, Yue

2016-01-01

Most patients with polycythemia vera (PV) and half of essential thrombocythemia (ET) possess an activating JAK2V617F mutation. The objective of this study was to better define the effect of JAK2V617F mutant allele burden on clinical phenotypes in Chinese patients, especially thrombosis. By real-time polymerase chain reaction (RT-PCR), the JAK2V617F mutation burden was detected in 170 JAK2V617F-positive patients, including 54 PV and 116 ET. The results showed that JAK2V617F allele burden was higher in PV than in ET (PET (68.5% VS 26.7%) (PET patients showed increased JAK2V617F allele burden in the group with higher hemoglobin (HGB above 150 g/L) (PET. In PV patients, JAK2V617F mutation burden had influence on WBC counts. And the clinical characteristics of ET patients, such as WBC counts, hemoglobin level, splenomegaly and thrombosis, were influenced by JAK2V617F mutation burden. Male, high hemoglobin (HGB above 150 g/L), and increased JAK2V617F mutation burden (JAK2V617F allele burden ≥ 16.5%) were risks of thrombosis (PET patients by Logistic Regression.

The 150 ns detector project: Prototype preamplifier results

Science.gov (United States)

Warburton, W. K.; Russell, S. R.; Kleinfelder, Stuart A.

1994-08-01

The long-term goal of the 150 ns detector project is to develop a pixel area detector capable of 6 MHz frame rates (150 ns/frame). Our milestones toward this goal are: a single pixel, 1×256 1D and 8×8 2D detectors, 256×256 2D detectors and, finally, 1024 × 1024 2D detectors. The design strategy is to supply a complete electronics chain (resetting preamp, selectable gain amplifier, analog-to-digital converter (ADC), and memory) for each pixel. In the final detectors these will all be custom integrated circuits. The front-end preamplifiers are integrated first, since their design and performance are the most unusual and also critical to the project's success. Similarly, our early work is concentrated on devising and perfecting detector structures. In this paper we demonstrate the performance of prototypes of our integrated preamplifiers. While the final design will have 64 preamps to a chip, including a switchable gain stage, the prototypes were integrated 8 channels to a "Tiny Chip" and tested in 4 configurations (feedback capacitor Cf equal 2.5 or 4.0 pF, output directly or through a source follower). These devices have been tested thoroughly for reset settling times, gain, linearity, and electronic noise. They generally work as designed, being fast enough to easily integrate detector charge, settle, and reset in 150 ns. Gain and linearity appear to be acceptable. Current values of electronic noise, in double-sampling mode, are about twice the design goal of {2}/{3} of a single photon at 6 keV. We expect this figure to improve with the addition of the onboard amplifier stage and improved packaging. Our next test chip will include these improvements and allow testing with our first detector samples, which will be 1×256 (50 μm wide pixels) and 8×8 (1 mm 2 pixels) element detector on 1 mm thick silicon.

The ArF laser for the next-generation multiple-patterning immersion lithography supporting green operations

Science.gov (United States)

Ishida, Keisuke; Ohta, Takeshi; Miyamoto, Hirotaka; Kumazaki, Takahito; Tsushima, Hiroaki; Kurosu, Akihiko; Matsunaga, Takashi; Mizoguchi, Hakaru

2016-03-01

Multiple patterning ArF immersion lithography has been expected as the promising technology to satisfy tighter leading edge device requirements. One of the most important features of the next generation lasers will be the ability to support green operations while further improving cost of ownership and performance. Especially, the dependence on rare gases, such as Neon and Helium, is becoming a critical issue for high volume manufacturing process. The new ArF excimer laser, GT64A has been developed to cope with the reduction of operational costs, the prevention against rare resource shortage and the improvement of device yield in multiple-patterning lithography. GT64A has advantages in efficiency and stability based on the field-proven injection-lock twin-chamber platform (GigaTwin platform). By the combination of GigaTwin platform and the advanced gas control algorithm, the consumption of rare gases such as Neon is reduced to a half. And newly designed Line Narrowing Module can realize completely Helium free operation. For the device yield improvement, spectral bandwidth stability is important to increase image contrast and contribute to the further reduction of CD variation. The new spectral bandwidth control algorithm and high response actuator has been developed to compensate the offset due to thermal change during the interval such as the period of wafer exchange operation. And REDeeM Cloud™, new monitoring system for managing light source performance and operations, is on-board and provides detailed light source information such as wavelength, energy, E95, etc.

32 CFR 150.6 - Signing of papers.

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Signing of papers. 150.6 Section 150.6 National... JUSTICE COURTS OF CRIMINAL APPEALS RULES OF PRACTICE AND PROCEDURE § 150.6 Signing of papers. All formal papers shall be signed and shall show, typewritten or printed, the signer's name, address, military grade...

21 CFR 160.150 - Frozen egg whites.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Frozen egg whites. 160.150 Section 160.150 Food... HUMAN CONSUMPTION EGGS AND EGG PRODUCTS Requirements for Specific Standardized Eggs and Egg Products § 160.150 Frozen egg whites. (a) Frozen egg whites, frozen egg albumen is the food prepared by freezing...

Operations Between Functions

DEFF Research Database (Denmark)

Gardner, Richard J.; Kiderlen, Markus

A structural theory of operations between real-valued (or extended-real-valued) functions on a nonempty subset A of Rn is initiated. It is shown, for example, that any operation ∗ on a cone of functions containing the constant functions, which is pointwise, positively homogeneous, monotonic......, and associative, must be one of 40 explicitly given types. In particular, this is the case for operations between pairs of arbitrary, or continuous, or differentiable functions. The term pointwise means that (f ∗g)(x) = F(f(x), g(x)), for all x ∈ A and some function F of two variables. Several results in the same...... spirit are obtained for operations between convex functions or between support functions. For example, it is shown that ordinary addition is the unique pointwise operation between convex functions satisfying the identity property, i.e., f ∗ 0 = 0 ∗ f = f, for all convex f, while other results classify Lp...

Pre- and post-irradiation fading effect for LiF:Mg,Ti and LiF:Mg,Cu,P materials used in routine monitoring

International Nuclear Information System (INIS)

Carinou, E.; Askounis, P.; Dimitropoulou, F.; Kiranos, G.; Kyrgiakou, H.; Nirgianaki, E.; Papadomarkaki, E.; Kamenopoulou, V.

2011-01-01

LiF is a well-known thermoluminescent (TL) material used in individual monitoring, and its fading characteristics have been studied for years. In the present study, the fading characteristics (for a period of 150 d) of various commercial LiF materials with different dopants have been evaluated. The materials used in the study are those used in routine procedures by the Personal Dosimetry Dept. of Greek Atomic Energy Commission and in particular, LiF:Mg,Ti (MTS-N, TL Poland), LiF:Mg,Cu,P (MCP-N, TL Poland), LiF:Mg,Cu,P (MCP-Ns, thin active layer detector, TL Poland) and LiF:Mg,Cu,P (TLD100H, Harshaw). The study showed that there is a sensitivity loss in signal of up to 20 % for the MTS-N material for a 150-d period in the pre-irradiation fading phase. The MCP-N has a stable behaviour in the pre-irradiation fading phase, but this also depends on the readout system. As far as the post-irradiation fading effect is concerned, a decrease of up to 20 % for the MTS-N material is observed for the same time period. On the other hand, the LiF:Mg,Cu,P material presents a stable behaviour within ±5 %. These results show that the fading effect is different for each material and should be taken into account when estimating doses from dosemeters that are in use for >2 months. (authors)

Two-neutrino double-β decay of 150Nd to excited final states in 150Sm

Science.gov (United States)

Kidd, M. F.; Esterline, J. H.; Finch, S. W.; Tornow, W.

2014-11-01

Background: Double-β decay is a rare nuclear process in which two neutrons in the nucleus are converted to two protons with the emission of two electrons and two electron antineutrinos. Purpose: We measured the half-life of the two-neutrino double-β decay of 150Nd to excited final states of 150Sm by detecting the deexcitation γ rays of the daughter nucleus. Method: This study yields the first detection of the coincidence γ rays from the 0 1+ excited state of 150Sm. These γ rays have energies of 333.97 and 406.52 keV and are emitted in coincidence through a 01+→21+→0gs+ transition. Results: The enriched Nd2O3 sample consisted of 40.13 g 150Nd and was observed for 642.8 days at the Kimballton Underground Research Facility, producing 21.6 net events in the region of interest. This count rate gives a half-life of T1 /2=[1 .07-0.25+0.45(stat ) ±0.07 (syst ) ] ×1020 yr. The effective nuclear matrix element was found to be 0.0465 -0.0054+0.0098. Finally, lower limits were obtained for decays to higher excited final states. Conclusions: Our half-life measurement agrees within uncertainties with another recent measurement in which no coincidence was employed. Our nuclear matrix element calculation may have an impact on a recent neutrinoless double-β decay nuclear matrix element calculation which implies that the decay to the first excited state in 150Sm is favored over that to the ground state.

44 CFR 150.3 - Nomination process.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Nomination process. 150.3 Section 150.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Nomination process. (a) The Nominating Officials nominating Firefighters and Civil Defense Officers shall...

40 CFR 1065.150 - Continuous sampling.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 32 2010-07-01 2010-07-01 false Continuous sampling. 1065.150 Section... ENGINE-TESTING PROCEDURES Equipment Specifications § 1065.150 Continuous sampling. You may use continuous sampling techniques for measurements that involve raw or dilute sampling. Make sure continuous sampling...

44 CFR 150.7 - Selection process.

Science.gov (United States)

2010-10-01

... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Selection process. 150.7 Section 150.7 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF... Selection process. (a) President's Award. Nominations for the President's Award shall be reviewed, and...

B 150 civil engineering futures

DEFF Research Database (Denmark)

Foreword B150 –Civil Engineering Futures consists of interviews made, articles written, and projects presented in connection with the 150th anniversary celebrations of the study of civil engineering in Denmark. Instead of a historical retrospect, it was decided to look into the future. What...... challenges will the next 150 years bring civil engineers? Researchers and lecturers at DTU’s Department of Civil Engineering (known as DTU Byg) suggested possible events, and we also consulted civil engineers and their business partners in the building industry. In this way, a programme was put together...... theme in twentieth century architecture. Together, civil engineer Peter Rice and architect Ian Ritchie created a paradigm shift with their revolutionary ideas for glass facades supported by cables. Glued and bolted constructions made entirely of glass are now a reality in small-scale projects, yet...

Fibered F-Algebra

OpenAIRE

Kleyn, Aleks

2007-01-01

The concept of F-algebra and its representation can be extended to an arbitrary bundle. We define operations of fibered F-algebra in fiber. The paper presents the representation theory of of fibered F-algebra as well as a comparison of representation of F-algebra and of representation of fibered F-algebra.

The design and performance of 150-MW S-band klystrons

International Nuclear Information System (INIS)

Sprehn, D.; Phillips, R.M.; Caryotakis, G.

1994-09-01

As part of an international collaboration, the Stanford Linear Accelerator Center (SLAC) klystron group has designed, fabricated and tested a 60 Hz, 3 μs, 150 MW klystron built for Deutsches Elektronen Synchrotron (DESY). A test diode with a 535 kV, 700 A electron beam was constructed to verify the gun operation. The first klystron was built and successfully met design specifications. This paper discusses design issues and experimental results of the diode and klystron including the suppression of gun oscillations

The KFKI 150 kV ion-implanter

International Nuclear Information System (INIS)

Pasztor, E.

1976-09-01

The description of the ion-implanter of 150 keV maximum energy designed and built in the Central Research Institute for Physics, Budapest is given. The implanter fulfils all technological and safety requirements of the industry. In addition to B,P and As other elements up to mass-number 76 can also be implanted by help of the Danfysik 911 type ion source. The 3x10 -6 Torr operational pressure is provided by three turbomolecular pumps. The maximum dose is 1 μCb/cm 2 min and to ensure uniformity of the implantation on the 100x105 mm 2 target area the ion beam is swept electrostatically. According to the testing experiments the inhomogenity can be taken to be +-1.3%. (Sz.N.Z.)

38 CFR 17.150 - Prosthetic and similar appliances.

Science.gov (United States)

2010-07-01

... appliances. 17.150 Section 17.150 Pensions, Bonuses, and Veterans' Relief DEPARTMENT OF VETERANS AFFAIRS MEDICAL Prosthetic, Sensory, and Rehabilitative Aids § 17.150 Prosthetic and similar appliances... appliances including invalid lifts and therapeutic and rehabilitative devices, and special clothing made...

B 150 civil engineering futures

DEFF Research Database (Denmark)

specific climatic challenge or clean the air. With nanotechnology, the artificial and the natural move closer together; this is the perspective for civil engineer Chris McCarthy’s work all over the world. And what is new is not just the way the construction materials are put together; they also require......Foreword B150 –Civil Engineering Futures consists of interviews made, articles written, and projects presented in connection with the 150th anniversary celebrations of the study of civil engineering in Denmark. Instead of a historical retrospect, it was decided to look into the future. What...... challenges will the next 150 years bring civil engineers? Researchers and lecturers at DTU’s Department of Civil Engineering (known as DTU Byg) suggested possible events, and we also consulted civil engineers and their business partners in the building industry. In this way, a programme was put together...

45 CFR 2490.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 4 2010-10-01 2010-10-01 false Program accessibility: Existing facilities. 2490.150 Section 2490.150 Public Welfare Regulations Relating to Public Welfare (Continued) JAMES MADISON... ACTIVITIES CONDUCTED BY THE JAMES MADISON MEMORIAL FELLOWSHIP FOUNDATION § 2490.150 Program accessibility...

Study of 150 cases of acute appendicitis in children

Directory of Open Access Journals (Sweden)

Fallahi Gh

1998-06-01

Full Text Available Acute appendicitis is the most common condidition, requiring emergency operation in children. Late appendicitis is still a major sours of morbidity and potential mortality. The charts of all pediatric appendectomy patients (150 cases treated between 1367-1373 (Iranian calender in Amir Kabir Medical Center were reviewed. Mean hospital stay was 4.7 days. Mean ages of patients was 8.5 years. Male to female ratio was 1.2/1. Most common symptom was abdominal pain (100% and deep tenderness in right lower quadrant in 94.6%. Mean temprature was 37.2 and leucocytosis (more than 10000 were in the 76.3%. 14 patients had perforated appendicitis and most common pathology was acut supporative appendicitis. Accuracy of diagnosis was 96.6% and post operative pelvic abccess was 2%. Mortality occurred in one case (0.6%

Experimental adaptation of wild-type canine distemper virus (CDV to the human entry receptor CD150.

Directory of Open Access Journals (Sweden)

Maria Bieringer

Full Text Available Canine distemper virus (CDV, a close relative of measles virus (MV, is widespread and well known for its broad host range. When the goal of measles eradication may be achieved, and when measles vaccination will be stopped, CDV might eventually cross the species barrier to humans and emerge as a new human pathogen. In order to get an impression how fast such alterations may occur, we characterized required adaptive mutations to the human entry receptors CD150 (SLAM and nectin-4 as first step to infect human target cells. Recombinant wild-type CDV-A75/17(red adapted quickly to growth in human H358 epithelial cells expressing human nectin-4. Sequencing of the viral attachment proteins (hemagglutinin, H, and fusion protein, F genes revealed that no adaptive alteration was required to utilize human nectin-4. In contrast, the virus replicated only to low titres (10(2 pfu/ml in Vero cells expressing human CD150 (Vero-hSLAM. After three passages using these cells virus was adapted to human CD150 and replicated to high titres (10(5 pfu/ml. Sequence analyses revealed that only one amino acid exchange in the H-protein at position 540 Asp→Gly (D540G was required for functional adaptation to human CD150. Structural modelling suggests that the adaptive mutation D540G in H reflects the sequence alteration from canine to human CD150 at position 70 and 71 from Pro to Leu (P70L and Gly to Glu (G71E, and compensates for the gain of a negative charge in the human CD150 molecule. Using this model system our data indicate that only a minimal alteration, in this case one adaptive mutation, is required for adaptation of CDV to the human entry receptors, and help to understand the molecular basis why this adaptive mutation occurs.

10 CFR 455.150 - Right to administrative review.

Science.gov (United States)

2010-01-01

... 10 Energy 3 2010-01-01 2010-01-01 false Right to administrative review. 455.150 Section 455.150 Energy DEPARTMENT OF ENERGY ENERGY CONSERVATION GRANT PROGRAMS FOR SCHOOLS AND HOSPITALS AND BUILDINGS OWNED BY UNITS OF LOCAL GOVERNMENT AND PUBLIC CARE INSTITUTIONS Administrative Review § 455.150 Right to...

Double-β decay Q value of 150Nd

International Nuclear Information System (INIS)

Kolhinen, V. S.; Eronen, T.; Gorelov, D.; Hakala, J.; Jokinen, A.; Kankainen, A.; Moore, I. D.; Rissanen, J.; Saastamoinen, A.; Suhonen, J.; Aeystoe, J.

2010-01-01

The double-β decay Q value of 150 Nd was determined by using the JYFLTRAP Penning trap mass spectrometer. The measured mass difference between 150 Nd and 150 Sm is 3371.38(20) keV. This new value deviates by 3.7 keV from the previously adopted value of 3367.7(22) keV and is a factor of 10 more precise. Accurate knowledge of this Q value is important because 150 Nd is a primary candidate to be used in the search for neutrinoless double-β decay modes in several experiments.

Preparation of A-150 tissue-equivalent plastic films

International Nuclear Information System (INIS)

Saion, E.B.; Shaari, A.H.; Watt, D.E.

1992-01-01

A-150 tissue-equivalent (TE) plastic is widely used as a wall material for tissue-equivalent proportional counters (TEPCS) used in experimental microdosimetry. The objective of this note is to give a technical account of how A-150 TE plastic film can be fabricated in the laboratory from commercially available A-150 TE plastic. (author)

CAREM project 15 to 150 MWe

International Nuclear Information System (INIS)

1992-05-01

The main goal of the Carem Project is the introduction of a Inherent Safe Nuclear Power Reactor in the range of low power (15 to 150 MWe). For this low-power application, light-water and low enriched uranium was selected, since using those concepts permits to take full advantage of the special characteristics of low power reactors. INVAP has been involved in the last years in the design and construction of a Carem Reactor, which could cover a range up to 150 MWe, using a multiple-unit approach. It would furnished the 150 MWe, using six Carem Reactors, of proper power, which would share most of the services. INVAP is a reliable supplier of not only the nuclear reactor but also of the fuel

A 35fJ/Step differential successive approximation capacitive sensor readout circuit with quasi-dynamic operation

KAUST Repository

Omran, Hesham

2016-10-06

We propose a successive-approximation capacitive sensor readout circuit that achieves 35fJ/Step energy efficiency FoM, which represents 4× improvement over the state-of-the-art. A fully differential architecture is employed to provide robustness against common mode noise and errors. An inverter-based amplifier with near-threshold biasing provides robust, fast, and energy-efficient operation. Quasi-dynamic operation is used to maintain the energy efficiency for a scalable sample rate. A hybrid coarse-fine capacitive DAC achieves 11.7bit effective resolution in a compact area. © 2016 IEEE.

32 CFR 150.5 - Place for filing papers.

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Place for filing papers. 150.5 Section 150.5... MILITARY JUSTICE COURTS OF CRIMINAL APPEALS RULES OF PRACTICE AND PROCEDURE § 150.5 Place for filing papers. When the filing of a notice of appearance, brief, or other paper in the office of a Judge Advocate...

High operating temperature interband cascade focal plane arrays

Energy Technology Data Exchange (ETDEWEB)

Tian, Z.-B.; Godoy, S. E.; Kim, H. S.; Schuler-Sandy, T.; Montoya, J. A.; Krishna, S. [Center for High Technology Materials, Department of Electrical and Computer Engineering, University of New Mexico, Albuquerque, New Mexico 87106 (United States)

2014-08-04

In this paper, we report the initial demonstration of mid-infrared interband cascade (IC) photodetector focal plane arrays with multiple-stage/junction design. The merits of IC photodetectors include low noise and efficient photocarrier extraction, even for zero-bias operation. By adopting enhanced electron barrier design and a total absorber thickness of 0.7 μm, the 5-stage IC detectors show very low dark current (1.10 × 10{sup −7} A/cm{sup 2} at −5 mV and 150 K). Even with un-optimized fabrication and standard commercial (mis-matched) read-out circuit technology, infrared images are obtained by the 320 × 256 IC focal plane array up to 180 K with f/2.3 optics. The minimum noise equivalent temperature difference of 28 mK is obtained at 120 K. These initial results indicate great potential of IC photodetectors, particularly for high operating temperature applications.

High operating temperature interband cascade focal plane arrays

International Nuclear Information System (INIS)

Tian, Z.-B.; Godoy, S. E.; Kim, H. S.; Schuler-Sandy, T.; Montoya, J. A.; Krishna, S.

2014-01-01

In this paper, we report the initial demonstration of mid-infrared interband cascade (IC) photodetector focal plane arrays with multiple-stage/junction design. The merits of IC photodetectors include low noise and efficient photocarrier extraction, even for zero-bias operation. By adopting enhanced electron barrier design and a total absorber thickness of 0.7 μm, the 5-stage IC detectors show very low dark current (1.10 × 10 −7 A/cm 2 at −5 mV and 150 K). Even with un-optimized fabrication and standard commercial (mis-matched) read-out circuit technology, infrared images are obtained by the 320 × 256 IC focal plane array up to 180 K with f/2.3 optics. The minimum noise equivalent temperature difference of 28 mK is obtained at 120 K. These initial results indicate great potential of IC photodetectors, particularly for high operating temperature applications

Syntheses, Raman spectra, and X-ray crystal structures of [XeF(5)][mu-F(OsO(3)F(2))(2)] and [M][OsO(3)F(3)] (M = XeF(5)(+), Xe(2)F(11)(+)).

Science.gov (United States)

Hughes, Michael J; Mercier, Hélène P A; Schrobilgen, Gary J

2010-04-05

the ion pairs, [Xe(2)F(11)][OsO(3)F(3)], [XeF(5)][OsO(3)F(3)], and [XeF(5)][mu-F(OsO(3)F(2))(2)], as well as those of the free ions, Xe(2)F(11)(+), XeF(5)(+), OsO(3)F(3)(-), and mu-F(OsO(3)F(2))(2)(-). The Raman spectra (-150 degrees C) of the salts have been assigned based on the ion pairs observed in the crystal structures and the calculated vibrational frequencies and intensities of the gas-phase ion pairs.

Evaluation of in-core neutron flux and temperature field measurements during the second period of power commissioning of the KS-150 reactor

International Nuclear Information System (INIS)

Rana, S.B.; Pecho, J.

1975-01-01

The in-core flux mapping system in the KS-150 reactor using mapping fuel elements with self-powered detectors is described. Experimental data evaluation using the Fourier analysis and determination of important operation parameters from the detectors and temperature field distribution using thermocouples for measuring coolant outlet temperatures and fuel temperatures are given. The DPZ-1 detectors used, mapping fuel elements and the method of signal registration are described. The results of operation of mapping fuel elements during the 2nd period of the KS-150 reactor commissioning are given. (author)

40 CFR 46.150 - Request for applications.

Science.gov (United States)

2010-07-01

... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Request for applications. 46.150 Section 46.150 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GRANTS AND OTHER FEDERAL... fellowship applications through electronic and printed announcements or other means designed to inform...

The Barley Magnesium Chelatase 150-kD Subunit Is Not an Abscisic Acid Receptor1[OA

Science.gov (United States)

Müller, André H.; Hansson, Mats

2009-01-01

Magnesium chelatase is the first unique enzyme of the chlorophyll biosynthetic pathway. It is composed of three gene products of which the largest is 150 kD. This protein was recently identified as an abscisic acid receptor in Arabidopsis (Arabidopsis thaliana). We have evaluated whether the barley (Hordeum vulgare) magnesium chelatase large subunit, XanF, could be a receptor for the phytohormone. The study involved analysis of recombinant magnesium chelatase protein as well as several induced chlorophyll-deficient magnesium chelatase mutants with defects identified at the gene and protein levels. Abscisic acid had no effect on magnesium chelatase activity and binding to the barley 150-kD protein could not be shown. Magnesium chelatase mutants showed a wild-type response in respect to postgermination growth and stomatal aperture. Our results question the function of the large magnesium chelatase subunit as an abscisic acid receptor. PMID:19176716

Reactions UF4 - ClO2F and UF5 - ClO2F

International Nuclear Information System (INIS)

Benoit, Raymond; Besnard, Ginette; Hartmanshenn, Olivier; Luce, Michel; Mougin, Jacques; Pelissie, Jean

1970-02-01

The study of the reaction UF 4 - ClO 2 F between 0 deg. and 100 deg. C, by various techniques (micro-sublimation, isopiestic method, IR and UV spectrography, thermogravimetry and X-ray diffraction) shows that intermediate steps are possible before the production of UF 5 . The whole reaction may be schematised by two equations: (1) n UF 4 + ClO 2 F → n UF x + ClO 2 (4 4 + ClO 2 F → UF x + 1/2 Cl 2 + O 2 . The more the temperature rises, the more the second equation becomes experimentally verified. The reaction at 0 deg. C between UF 5 and ClO 2 F may be represented by: UF 5 + ClO 2 F → UF 6 ClO 2 . The reactions: UF 5 + ClO 2 F → UF 6 + ClO 2 , UF 5 + ClO 2 F → UF 6 + 1/2 Cl 2 + O 2 are verified, the first and the second at 25 deg. C., the second from 50 deg. to 150 deg. C. From the results of AGRON it is possible to predict the residual solids before complete volatilization as UF 6 . The IR spectra of ClO 2 F adsorbed on UF 4 and UF x at 60 deg. C have been compared with those of gaseous ClO 2 F and UF 6 adsorbed on UF 4 . (authors) [fr

150 aastat papa Jannsenist

Index Scriptorium Estoniae

2007-01-01

2007. a. möödub 150 aastat Johann Voldemar Jannseni asutatud Pärnu Postimehe 1. numbri ilmumisest. Selle tähistamiseks avatakse Pärnus Rüütli tänava muulil 5. juunil 2007 Jannseni kuju (skulptor Mati Karmin)

The future of A-150 TE plastic

International Nuclear Information System (INIS)

Goodman, L.J.

1985-01-01

For the past 26 years a large number of laboratories have constructed or purchased ionization chambers, proportional counters, and phantoms made of A-150 tissue-equivalent plastic, and they have amassed a considerable amount of data and experience in its properties and uses. The United States National Bureau of Standards is now considering the desirability of supplying A-150 plastic as a research material with a certified homogeneity. We are, however, faced with a problem since the nylon used in A-150 has been discontinued by the manufacturer and the current stock of A-150 has been estimated to be adequate to supply the demand for only the next 2 or 3 years. Thus, it will be necessary to reformulate the plastic mixture we will be using in the future. This situation offers us the opportunity to change the composition of tissue-equivalent plastic to better conform to present-day requirements. To elucidate just what these requirements are, we have conducted a postal survey of the opinions of neutron dosimetrists and the results are presented and discussed. It is concluded that the present A-150 plastic and a future tissue-equivalent plastic formulation should be made research materials, and that a future tissue-equivalent plastic should be made to conform as closely as possible to the soft tissue composition given in ICRU Report 33

33 CFR 138.150 - Service of process.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Service of process. 138.150... Pollution (Vessels) § 138.150 Service of process. (a) When executing the forms required by this subpart... as its agent for service of process for purposes of this subpart and for receipt of notices of...

40 CFR 82.150 - Purpose and scope.

Science.gov (United States)

2010-07-01

...) PROTECTION OF STRATOSPHERIC OZONE Recycling and Emissions Reduction § 82.150 Purpose and scope. (a) The purpose of this subpart is to reduce emissions of class I and class II refrigerants and their substitutes... 40 Protection of Environment 17 2010-07-01 2010-07-01 false Purpose and scope. 82.150 Section 82...

Operation of a T63 Turbine Engine Using F24 Contaminated Skydrol 5 Hydraulic Fluid

Science.gov (United States)

2016-09-01

hydraulic fluids were originally developed by the Douglas Aircraft Company during the 1940s to reduce fire risk from leaking high pressure mineral oil...thermal load demands in modern hydraulic systems and reduced density to lower weight impact on the aircraft. Eastman Chemical is the current producer of...AFRL-RQ-WP-TM-2016-0155 OPERATION OF A T63 TURBINE ENGINE USING F24 CONTAMINATED SKYDROL 5 HYDRAULIC FLUID Matthew J. Wagner (AFRL/RQTM) James

41 CFR 105-8.150-2 - Methods.

Science.gov (United States)

2010-07-01

... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Methods. 105-8.150-2... HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY GENERAL SERVICES ADMINISTRATION § 105-8.150-2 Methods. (a... construction of new facilities, use of accessible rolling stock, or any other methods that result in making its...

42 CFR 456.150 - Scope.

Science.gov (United States)

2010-10-01

... ASSISTANCE PROGRAMS UTILIZATION CONTROL Utilization Control: Mental Hospitals § 456.150 Scope. This subpart prescribes requirements for control of utilization of inpatient services in mental hospitals, including...

Common brain regions underlying different arithmetic operations as revealed by conjunct fMRI-BOLD activation.

Science.gov (United States)

Fehr, Thorsten; Code, Chris; Herrmann, Manfred

2007-10-03

The issue of how and where arithmetic operations are represented in the brain has been addressed in numerous studies. Lesion studies suggest that a network of different brain areas are involved in mental calculation. Neuroimaging studies have reported inferior parietal and lateral frontal activations during mental arithmetic using tasks of different complexities and using different operators (addition, subtraction, etc.). Indeed, it has been difficult to compare brain activation across studies because of the variety of different operators and different presentation modalities used. The present experiment examined fMRI-BOLD activity in participants during calculation tasks entailing different arithmetic operations -- addition, subtraction, multiplication and division -- of different complexities. Functional imaging data revealed a common activation pattern comprising right precuneus, left and right middle and superior frontal regions during all arithmetic operations. All other regional activations were operation specific and distributed in prominently frontal, parietal and central regions when contrasting complex and simple calculation tasks. The present results largely confirm former studies suggesting that activation patterns due to mental arithmetic appear to reflect a basic anatomical substrate of working memory, numerical knowledge and processing based on finger counting, and derived from a network originally related to finger movement. We emphasize that in mental arithmetic research different arithmetic operations should always be examined and discussed independently of each other in order to avoid invalid generalizations on arithmetics and involved brain areas.

Characteristics of A-150 plastic equivalent gas in A-150 plastic ionization chambers for p(66)Be(49) neutrons

International Nuclear Information System (INIS)

Awschalom, M.; Rosenberg, I.; Ten Haken, R.K.; Pearson, D.W.; DeLuca, P.M. Jr.; Attix, F.H.

1982-01-01

The average energy necessary to produce an electron-ion pair (anti W) of a gas mixture having an atomic composition very close to that of A-150 plastic has been studied through use in different size ionization chambers made of that plastic in a p(66)Be(49) neutron therapy beam. A tentative value for anti W(A-150-gas) of 27.3 +/ -0.5 J C -1 was derived. The anti W value of the A-150 equivalent gas mixture is compared to those of methane-based tissue-equivalent gas and of air for the p(66)Be(49) neutron beam as well as to corresponding values found in similar experiments using 14.8 MeV monoenergetic neutrons

Magnetic activity effect on equatorial spread-F under high and low solar activity conditions

Energy Technology Data Exchange (ETDEWEB)

Subbarao, K S.V.; Somayajulu, V V; Krishna Murthy, B V

1986-08-01

The effect of magnetic activity on spread-F at two equatorial stations, Trivandrum and Huancayo, separated in longitude by about 150 deg, under high and low solar activity conditions has been investigated. Magnetic activity produces strong inhibition effect on spread-F at Huancayo compared to that at Trivandrum especially during high solar activity period. This results in a decrease of spread-F with solar activity at Huancayo in contrast to Trivandrum. These findings are explained in terms of F-region electrodynamics and Rayleigh-Taylor instability mechanism for spread-F.

Nuclear facilities of EdF's operational hot base of Tricastin. 2009 annual report

International Nuclear Information System (INIS)

2010-01-01

This annual report is established on account of article 21 of the 2006-686 French law from June 13, 2006, relative to the transparency and safety in the nuclear domain. It describes, first, the nuclear facilities of the EdF operational hot base of Tricastin, then, the measures taken to ensure their safety (personnel radioprotection, actions implemented for nuclear safety improvement, organisation in crisis situation, external and internal controls, technical assessment of the facilities), and finally the procedures of management of radioactive wastes. A glossary and the viewpoint of the Committee of Hygiene, safety and working conditions about the content of the document conclude the report. (J.S.)

NiF2/NaF:CaF2/Ca Solid-State High-Temperature Battery Cells

Science.gov (United States)

West, William; Whitacre, Jay; DelCastillo, Linda

2009-01-01

Experiments and theoretical study have demonstrated the promise of all-solid-state, high-temperature electrochemical battery cells based on NiF2 as the active cathode material, CaF2 doped with NaF as the electrolyte material, and Ca as the active anode material. These and other all-solid-state cells have been investigated in a continuing effort to develop batteries for instruments that must operate in environments much hotter than can be withstood by ordinary commercially available batteries. Batteries of this type are needed for exploration of Venus (where the mean surface temperature is about 450 C), and could be used on Earth for such applications as measuring physical and chemical conditions in geothermal wells and oil wells. All-solid-state high-temperature power cells are sought as alternatives to other high-temperature power cells based, variously, on molten anodes and cathodes or molten eutectic salt electrolytes. Among the all-solid-state predecessors of the present NiF2/NaF:CaF2/Ca cells are those described in "Solid-State High-Temperature Power Cells" (NPO-44396), NASA Tech Briefs, Vol. 32, No. 5 (May 2008), page 40. In those cells, the active cathode material is FeS2, the electrolyte material is a crystalline solid solution of equimolar amounts of Li3PO4 and LiSiO4, and the active anode material is Li contained within an alloy that remains solid in the intended high operational temperature range.

Production and characterization of anti-human IgG F(ab')2 antibody fragment.

Science.gov (United States)

Valedkarimi, Zahra; Nasiri, Hadi; Aghebati-Maleki, Leili; Abdolalizadeh, Jalal; Esparvarinha, Mojghan; Majidi, Jafar

2018-04-10

In present study an optimized protocol for the separation of antibodies into antigen-binding fragments F(ab')2 using pepsin digestion was investigated. The production of these fragments is a consequential step in the development of medical research, treatment and diagnosis. For production of polyclonal antibody rabbit received antigen in four steps. The rabbit serum at 1/128000 dilution showed high absorbance in reaction with human IgG at the designed ELISA method. Rabbit IgG was purified by Ion-Exchange Chromatography (IEC) method. Purity was assessed by SDS-PAGE method. In non-reduced condition only one band was seen in about 150 kDa MW position and in reduced form, two bands were seen in 50 and 25 kDa MW positions. Rabbit IgG was digested by pepsin enzyme. The antibody fragments solution was applied to Gel filtration column to isolate the F(ab')2. Non-reduced SDS-PAGE for determining the purity of F(ab')2 fragment resulted in one band in 100 kDa corresponds to F(ab')2 fragment and a band in 150 kDa MW position corresponds to undigested IgG antibodies. The activities of FITC conjugated F(ab')2 fragment and commercial ones were compared using flowcytometry method. The activity results implied that the FITC conjugated- anti human F(ab')2 fragment worked as efficiently as the commercial one.

22 CFR 711.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-04-01

... result in a fundamental alteration in the nature of a program or activity or in undue financial and....150 Section 711.150 Foreign Relations OVERSEAS PRIVATE INVESTMENT CORPORATION ADMINISTRATIVE PROVISIONS ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY...

46 CFR 180.150 - Survival craft embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 7 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 180.150 Section... (UNDER 100 GROSS TONS) LIFESAVING EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 180.150 Survival craft embarkation arrangements. (a) A launching appliance approved under approval...

150 years of science

Directory of Open Access Journals (Sweden)

Francesca Messina

2011-08-01

Full Text Available This preview of the Festival della Scienza 2011 focuses on a major initiative celebrating 150 years of Italian scientific research. Run jointly by the Italian Research Council (CNR and the Associazione Festival della Scienza, the project presents outstanding achievements in various fields including neuroscience, web technologies, genetics, chemistry and much more.

5 CFR 1636.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-01-01

... fundamental alteration in the nature of a program or activity or in undue financial and administrative burdens... facilities. 1636.150 Section 1636.150 Administrative Personnel FEDERAL RETIREMENT THRIFT INVESTMENT BOARD ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE FEDERAL...

21 CFR 150.141 - Artificially sweetened fruit jelly.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Artificially sweetened fruit jelly. 150.141 Section 150.141 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES... locust bean gum), guar gum, gum karaya, gum tragacanth, algin (sodium alginate), sodium...

49 CFR 28.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-10-01

... 49 Transportation 1 2010-10-01 2010-10-01 false Program accessibility: Existing facilities. 28.150 Section 28.150 Transportation Office of the Secretary of Transportation ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY THE DEPARTMENT OF TRANSPORTATION § 28...

Addendum 2 to CSER 79-002: Extension of the 150 gram fissile limit used in room 187 of PFP

International Nuclear Information System (INIS)

Friar, D.E.

1994-01-01

The PFP operating organization requests that the limit set permitting 150 grams fissile be extended to the Hoods 4 and 5 of Room 187. The request for the limit change is explained in the attached request for analysis

10 CFR 72.150 - Instructions, procedures, and drawings.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Instructions, procedures, and drawings. 72.150 Section 72... WASTE Quality Assurance § 72.150 Instructions, procedures, and drawings. The licensee, applicant for a... documented instructions, procedures, or drawings of a type appropriate to the circumstances and shall require...

Dose rate and total dose dependence of the 1/f noise performance of a GaAs operational amplifier during irradiation

International Nuclear Information System (INIS)

Hiemstra, D.M.

1995-01-01

A pictorial of a sectioned view of the torus of the International Thermonuclear Experimental Reactor (ITER) is shown. Maintenance and inspection of the reactor are required to be performed remotely. This is due to the high gamma radiation environment in vessel during inspection and maintenance activities. The custom GaAs operational amplifier is to be used to readout sensors on the in-vessel manipulator and inspection equipment. The gamma dose rate during maintenance and inspection is anticipated to be 3 Mrad(GaAs)/hour. Here, dose rate and total dose dependence of the 1/f noise performance of a custom GaAs MESFET operational amplifier during irradiation are presented. Dose rate dependent 1/f noise degradation during irradiation is believed to be due to electron trapping in deep levels, enhanced by backgating and shallow traps excited during irradiation. The reduction of this affect with accumulated total dose is believed to be due a reduction of deep level site concentration associated with substitutional oxygen. Post irradiation 1/f noise degradation is also presented.The generation-recombination noise observed post irradiation can be attributed to the production of shallow traps due to ionizing radiation

12 CFR 410.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-01-01

... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Program accessibility: Existing facilities. 410.150 Section 410.150 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES ENFORCEMENT OF NONDISCRIMINATION ON THE BASIS OF HANDICAP IN PROGRAMS OR ACTIVITIES CONDUCTED BY EXPORT-IMPORT BANK OF THE UNITED...

46 CFR 117.150 - Survival craft embarkation arrangements.

Science.gov (United States)

2010-10-01

... 46 Shipping 4 2010-10-01 2010-10-01 false Survival craft embarkation arrangements. 117.150 Section... EQUIPMENT AND ARRANGEMENTS Survival Craft Arrangements and Equipment § 117.150 Survival craft embarkation... apparatus when either— (1) The embarkation station for the survival craft is on a deck more than 4.5 meters...

Measurement of solubility of plutonium trifluoride and rare-earth fluorides in molten LiF-BeF2-ZrF4

International Nuclear Information System (INIS)

Naumov, V.S.; Bychkov, A.V.; Kormilitsyn, M.V.

1996-12-01

Data on behavior of plutonium fluoride and fission products (FP) dissolved in fuel composition are needed to calculate the duration of an operating cycle of the ADTT facility (Accelerator-Driver Transmutation Technologies) and to determine the effect of their equilibrium concentrations on nuclear-physical characteristics of reactor operation. The data on the FP fluoride solubility in the molten salts are of great important for some industrial processes (electrolytical metal deposition, development of physical-chemical mean for processes of chemical technology, etc.) As noted above, some information on this question is given in monography and articles. Data concerning fluoride salts are given in reports. However, it was impossible to make the substantial analysis of mutual solubility of fluoride melts. The primary investigation of CeF 3 and neodymium, samarium and lanthanum fluorides showed that the solubility of the melt LiF-BeF 2 and LiF-BeF 2 -ThF 4 was a linear function of reverse temperature and increases from lanthanum to samarium in the row of rare-earth elements. Disagreement in estimation of plutonium trifluoride solubility and incomplete data on the solubility of rare-earth elements prompted this study

150-MW S-Band klystron program at the Stanford Linear Accelerator Center

Energy Technology Data Exchange (ETDEWEB)

Sprehn, D.; Caryotakis, G.; Phillips, R.M. [Stanford Linear Accelerator Center, Stanford Univ., Stanford, CA (United States)

1997-04-01

Two S-Band klystrons operating at 150 MW have been designed, fabricated and tested at the Stanford Linear Accelerator Center (SLAC) during the past two years for use in an experimental accelerator at Deutsches Elektronen Synchrotron (DESY) in Hamburg, Germany. Both klystrons operate at the design power, 60 Hz repetition rate, 3 {mu}s pulsewidth, with an efficiency > 40%, and agreement between the experimental results and simulations is excellent. The 535 kV, 700 A electron gun was tested by constructing a solenoidal focused beam-stick which identified a source of oscillation, subsequently engineered out of the klystron guns. Design of the beam-stick and the two klystrons is discussed, along with observation and suppression of spurious oscillations. Differences in design and the resulting performance of the klystrons is emphasized. (author)

Numerical Investigation for the Plasma Coal Gasifier of 150kW and 1400kW

Energy Technology Data Exchange (ETDEWEB)

Choi, Hyeong Yeong; Suh, Jae Seung [Hannam University, Daejeon (Korea, Republic of); Lho, Tai Hyeop [National Fusion Research Institute, Daejeon (Korea, Republic of)

2016-05-15

This study has verification of simulation for the gasifier of 150kWe and focuses on prediction of performance for the gasifier of 1.4MWe with a computational fluid dynamics (CFD) method. It is possible to predict flow patterns, tracks of particles, combustion characteristics, temperature distributions and chemical distributions using the commercial CFD solver ANSYS/FLUENT. Integrated coal gasification combined cycle (IGCC) has gained a lot of interest because they can produce cleaner gaseous fuels such as hydrogen, carbon monoxide and methane. Therefore, the National Fusion Research Institute (NFRI) plant has been investigating the application of their plasma technology to gasify coal. It is a fusion plasma technology for better efficiency of low-carbon fuels. They recently completed experiment for the gasifier of 150kwe, and are currently trying experiment for the gasifier of 1.4MWe. They have tried to design the gasifier that has cold gases of a higher efficiency. However it is considerably complicated and expensive that performance of gasifier is experimentally studied, because it is difficult to measure or control gases of very high temperature. This study has numerical investigation for the phenomena of coal gasification for coal gasifier of 150kWe and 1.4MWe at experiment operating conditions. This study has verification of simulation for the gasifier of 150kWe, and predicts performance for the gasifier of 1.4MWe. The gasifier of 1.4MWe will have a cold gas of higher efficiency than gasifier of 150kWe because can generate many hydrogen gas. So this gasification has the potential to become cornerstone technology in many hydrogen industries.

21 CFR 146.150 - Canned concentrated orange juice.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Canned concentrated orange juice. 146.150 Section... Fruit Juices and Beverages § 146.150 Canned concentrated orange juice. (a) Canned concentrated orange... labeling of ingredients prescribed for frozen concentrated orange juice by § 146.146, except that it is not...

10 CFR 150.7 - Persons in offshore waters not exempt.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Persons in offshore waters not exempt. 150.7 Section 150.7... AGREEMENT STATES AND IN OFFSHORE WATERS UNDER SECTION 274 Continued Commission Regulatory Authority in Offshore Waters § 150.7 Persons in offshore waters not exempt. Persons in offshore waters are not exempt...

Design, fabrication, test, and evaluation of a prototype 150-foot long composite wind turbine blade

Science.gov (United States)

Gewehr, H. W.

1979-01-01

The design, fabrication, testing, and evaluation of a prototype 150 foot long composite wind turbine blade is described. The design approach and material selection, compatible with low cost fabrication methods and objectives, are highlighted. The operating characteristics of the blade during rotating and nonrotating conditions are presented. The tensile, compression, and shear properties of the blade are reported. The blade fabrication, tooling, and quality assurance are discussed.

Synthesis, radiofluorination, and preliminary evaluation of the potential 5-HT2A receptor agonists [18 F]Cimbi-92 and [18 F]Cimbi-150

DEFF Research Database (Denmark)

Edgar, Fraser Graeme; Hansen, Hanne D; Leth-Petersen, Sebastian

2017-01-01

An agonist PET tracer is of key interest for the imaging of the 5-HT2A receptor, as exemplified by the previously reported success of [11 C]Cimbi-36. Fluorine-18 holds several advantages over carbon-11, making it the radionuclide of choice for clinical purposes. In this respect, an 18 F-labelled ......An agonist PET tracer is of key interest for the imaging of the 5-HT2A receptor, as exemplified by the previously reported success of [11 C]Cimbi-36. Fluorine-18 holds several advantages over carbon-11, making it the radionuclide of choice for clinical purposes. In this respect, an 18 F......-labelled agonist 5-HT2A receptor (5-HT2A R) tracer is highly sought after. Herein, we report a 2-step, 1-pot labelling methodology of 2 tracer candidates. Both ligands display high in vitro affinities for the 5-HT2A R. The compounds were synthesised from easily accessible labelling precursors, and radiolabelled...

Combined 18F-NaF and 18F-FDG PET/CT in the Evaluation of Sarcoma Patients.

Science.gov (United States)

Jackson, Tatianie; Mosci, Camila; von Eyben, Rie; Mittra, Erik; Ganjoo, Kristen; Biswal, Sandip; Gambhir, Sanjiv Sam; Iagaru, Andrei

2015-09-01

The combined administration of F-NaF and F-FDG in a single PET/CT scan has the potential to improve patient convenience and cancer detection. Here we report the use of this approach for patients with sarcomas. This is a retrospective review of 21 patients (12 men, 9 women; age, 19-66 years) with biopsy-proven sarcomas who had separate F-NaF PET/CT, F-FDG PET/CT, and combined F-NaF/F-FDG PET/CT scans for evaluation of malignancy. Two board-certified nuclear medicine physicians and 1 board-certified musculoskeletal radiologist were randomly assigned to review the scans. Results were analyzed for sensitivity and specificity, using linear regression and receiver operating characteristics. A total of 13 patients had metastatic disease on F-NaF PET/CT, F-FDG PET/CT, and combined F-NaF/F-FDG PET/CT. Skeletal disease was more extensive on the F-NaF PET/CT scan than on the F-FDG PET/CT in 3 patients, whereas in 1 patient, F-FDG PET/CT showed skeletal disease and the F-NaF PET/CT was negative. Extraskeletal lesions were detected on both F-FDG and combined F-NaF/F-FDG PET/CT in 20 patients, with 1 discordant finding in the lung. The combined F-NaF/F-FDG PET/CT scan allows for accurate evaluation of sarcoma patients. Further evaluation of this proposed imaging modality is warranted to identify the most suitable clinical scenarios, including initial treatment strategy and evaluation of response to therapy.

Determination of tea fluorine concentration with 19F(p, αγ)16O prompt nuclear reaction analysis

International Nuclear Information System (INIS)

Liang Daihua; Shen Guantao; Li Deyi; Wu Junheng

1987-01-01

Experiments of 19 F(p, αγ) 16 O prompt nuclear reaction analyses of tea F contents were performed on a Cockroft-Walton accelerator. The principle and apparatus are described. More than 150 varieties tea samples were examined. Results show that for the same variety of tea samples, the higher the grade of the tea, the higher the F concentration it contains, and for different varieties, the better the tea, the lower the F concentration of the tea

Cleanup Verification Package for the 118-F-7, 100-F Miscellaneous Hardware Storage Vault

International Nuclear Information System (INIS)

Appel, M.J.

2006-01-01

This cleanup verification package documents completion of remedial action for the 118-F-7, 100-F Miscellaneous Hardware Storage Vault. The site consisted of an inactive solid waste storage vault used for temporary storage of slightly contaminated reactor parts that could be recovered and reused for the 100-F Area reactor operations

Cleanup Verification Package for the 118-F-7, 100-F Miscellaneous Hardware Storage Vault

Energy Technology Data Exchange (ETDEWEB)

M. J. Appel

2006-11-02

This cleanup verification package documents completion of remedial action for the 118-F-7, 100-F Miscellaneous Hardware Storage Vault. The site consisted of an inactive solid waste storage vault used for temporary storage of slightly contaminated reactor parts that could be recovered and reused for the 100-F Area reactor operations.

7 CFR 915.150 - Reports.

Science.gov (United States)

2010-01-01

... inspected for the fresh avocado market. In addition, each handler shall provide the number of avocados... and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE AVOCADOS GROWN IN SOUTH FLORIDA Rules and Regulations § 915.150 Reports. (a) Each handler shall file with the Avocado Administrative...

21 CFR 556.150 - Chlortetracycline.

Science.gov (United States)

2010-04-01

... DRUGS, FEEDS, AND RELATED PRODUCTS TOLERANCES FOR RESIDUES OF NEW ANIMAL DRUGS IN FOOD Specific Tolerances for Residues of New Animal Drugs § 556.150 Chlortetracycline. (a) Acceptable daily intake (ADI... established for the sum of tetracycline residues in tissues of beef cattle, nonlactating dairy cows, calves...

40 CFR 161.150 - General.

Science.gov (United States)

2010-07-01

... FOR REGISTRATION OF ANTIMICROBIAL PESTICIDES Product Chemistry Data Requirements § 161.150 General. (a) Applicability. This subpart describes the product chemistry data that are required to support the registration... characteristics must be considered. (iv) Certain data are needed as basic or supportive evidence in initiating or...

Report of the reactor Operators Service - Annex F

International Nuclear Information System (INIS)

Zivotic, Z.

1990-01-01

RA reactor operators service is organized in two groups: permanent staff (chief operator, chief shift operators and operators) and changeable group which is formed according to the particular operation needs for working in shifts. During 1989 the operators service staff participated in the following activities: reconstruction of the existing reactor systems, control of the emergency cooling system, construction of the experimental loop 'Vinca-1'. Education of the staff was organized through routine courses, practical training is foreseen for 1991 [sr

Application of A150-plastic equivalent gases in microdosimetric measurements

International Nuclear Information System (INIS)

DeLuca, P.M. Jr.; Higgins, P.D.; Pearson, D.W.; Schell, M.; Attix, F.H.

1981-01-01

Neutron dosimetry measurements with ionization chambers, for the most part, employ tissue equivalent plastic-walled cavities (Shonka A150) filled with either air or a methane-base tissue-like gas. The atomic composition of TE-gas and A150 plastic are not matched and are quite dissimilar from muscle. Awschalom and Attix (1980) have partially resolved the problem by formulating a novel A150-plastic equivalent gas. This establishes a homogeneous wall-gas cavity dosimeter for neutron measurements and confines the necessary corrections to the applications of kerma ratios. In this report, we present measurements of applications of two A150-plastic equivalent gases in a low pressure spherical proportional counter. Gas gains and alpha-particle resolutions were determined. For these A150-mixtures as well as a methane-based TE-gas and an Ar-CO 2 mixture, we report measurements of event size distributions from exposure to a beam of 14.8 MeV neutrons

Operational trial of ParaSight-F (dipstick) in the diagnosis of falciparum malaria at the primary health care level.

Science.gov (United States)

Banchongaksorn, T; Prajakwong, S; Rooney, W; Vickers, P

1997-06-01

The rapid manual ParaSight-F test of Plasmodium falciparum malaria, an antigen capture test for detecting trophozoite-derived histidine rich protein-2 (PF HRP-2), is simple to perform and provides a definite diagnosis within 10 minutes. During an operational trial at health centers and mobile malaria units where microscopical diagnosis is not available and using defined symptom screening criteria, 3,361 subjects were tested yielding 618 positives (18.4%) for PF-HRP-2 by ParaSight-F. Microscopic examination of the same subjects by thick blood film examined 7 days later at a malaria clinic showed 578 falciparum, and 349 vivax and mixed infection (F+V) 41. The technology proved highly effective in detecting falciparum malaria at the peripheral levels where access to malaria laboratory services are difficult, thus allowing immediate administration of a complete course of treatment in the absence of a microscopic examination.

Report of the reactor Operators Service - Annex F

International Nuclear Information System (INIS)

Zivotic, Z.

1992-01-01

RA reactor operators service is organized in two groups: permanent staff (chief operator, chief shift operators and operators) and changeable group which is formed according to the particular operation needs for working in shifts. For continuous training of the existing operator staff the Service has prepared and published eleven booklets: Nuclear reactor; RA reactor primary coolant loop; System for purification of heavy water; reactor helium system; system for technical water; electric power system; control and operation; ventilation system in the reactor building; special sewage system; construction properties of the reactor core; reactor building and installations. During the reporting period there have been no accidents nor incidents that could affect the reactor personnel [sr

10 CFR 600.150 - Purpose of reports and records.

Science.gov (United States)

2010-01-01

... recipient's financial and program performance and the necessary standard reporting forms. They also set... 10 Energy 4 2010-01-01 2010-01-01 false Purpose of reports and records. 600.150 Section 600.150 Energy DEPARTMENT OF ENERGY (CONTINUED) ASSISTANCE REGULATIONS FINANCIAL ASSISTANCE RULES Uniform...

Fluoride production in RPCs operated with F-compound gases

International Nuclear Information System (INIS)

Aielli, G.; Camarri, P.; Cardarelli, R.; Di Ciaccio, A.; Di Simone, A.; Liberti, B.; Palummo, L.; Santonico, R.

2006-01-01

The Resistive Plate Chambers (RPC) are gaseous detectors widely used in LCH experiments for muon trigger systems and time of flight measurement due to their very good time resolution. Gas mixtures with a prevalence of HFC components are generally adjoint used to achieve a lower charge per count an consequently an higher rate capability. The decomposition of HFC under electrical discharge produces a significant concentration of fluorine ions F - that can be detected in the RPC exhausted gas. Due to the high chemical reactivity, this pollutant represents a possible cause of the inner surface damaging if it not quickly removed by the gas flow. In this paper various aspects of this phenomenology are investigated. We measured the F - production rate as a function of the detector counting rate and the working point (both in streamer and avalanche mode). The effect of the addition of 0.5% of SF 6 to the test mixture is also shown. We also extensively investigated the ratio between the F - production associated to a the time integral of the working current

Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells

Energy Technology Data Exchange (ETDEWEB)

Wang, Guanyu [Department of General Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou (China); Liu, Luying [Department of Radiotherapy, Zhejiang Cancer Hospital, Hangzhou (China); Sharma, Sherven [David Geffen School of Medicine at UCLA, and the Department of Veterans Affairs, Los Angeles, CA (United States); Liu, Hai; Yang, Weifang; Sun, Xiaonan [Department of Radiotherapy, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou (China); Dong, Qinghua, E-mail: dongqinghua@zju.edu.cn [Biomedical Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou (China)

2012-08-24

Highlights: Black-Right-Pointing-Pointer Adaptive radioresistant KYSE-150R cells expressed high level of Bmi-1. Black-Right-Pointing-Pointer Bmi-1 depletion sensitized KYSE-150R cells to RT. Black-Right-Pointing-Pointer Bmi-1 depletion increased the generation of ROS in KYSE-150R cells exposed to radiation. Black-Right-Pointing-Pointer Bmi-1 depletion impaired DNA repair capacities in KYSE-150R cells exposed to radiation. -- Abstract: Radiotherapy (RT) is a major modality of cancer treatment. However, tumors often acquire radioresistance, which causes RT to fail. The exact mechanisms by which tumor cells subjected to fractionated irradiation (FIR) develop an adaptive radioresistance are largely unknown. Using the radioresistant KYSE-150R esophageal squamous cell carcinoma (ESCC) model, which was derived from KYSE-150 parental cells using FIR, the role of Bmi-1 in mediating the radioadaptive response of ESCC cells to RT was investigated. The results showed that the level of Bmi-1 expression was significantly higher in KYSE-150R cells than in the KYSE-150 parental cells. Bmi-1 depletion sensitized the KYSE-150R cells to RT mainly through the induction of apoptosis, partly through the induction of senescence. A clonogenic cell survival assay showed that Bmi-1 depletion significantly decreased the radiation survival fraction in KYSE-150R cells. Furthermore, Bmi-1 depletion increased the generation of reactive oxygen species (ROS) and the expression of oxidase genes (Lpo, Noxo1 and Alox15) in KYSE-150R cells exposed to irradiation. DNA repair capacities assessed by {gamma}-H2AX foci formation were also impaired in the Bmi-1 down-regulated KYSE-150R cells. These results suggest that Bmi-1 plays an important role in tumor radioadaptive resistance under FIR and may be a potent molecular target for enhancing the efficacy of fractionated RT.

CW and femtosecond operation of a diode-pumped Yb:BaY(2)F(8) laser.

Science.gov (United States)

Galzerano, G; Coluccelli, N; Gatti, D; Di Lieto, A; Tonelli, M; Laporta, P

2010-03-15

We report for the first time on laser action of a diode-pumped Yb:BaY(2)F(8) crystal. Both CW and femtosecond operations have been demonstrated at room-temperature conditions. A maximum output power of 0.56 W, a slope efficiency of 34%, and a tunability range from 1013 to 1067 nm have been obtained in CW regime. Transform-limited pulse trains with a minimum duration of 275 fs, an average power of 40 mW, and a repetition rate of 83 MHz have been achieved in a passive mode-locked regime using a semiconductor saturable absorber mirror.

10 CFR 150.20 - Recognition of Agreement State licenses.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Recognition of Agreement State licenses. 150.20 Section 150.20 Energy NUCLEAR REGULATORY COMMISSION (CONTINUED) EXEMPTIONS AND CONTINUED REGULATORY AUTHORITY... the activities authorized, for an unlimited period of time. (5) Shall comply with all terms and...

Development and operation of a 6LiF:ZnS(Ag)-scintillating plastic capture-gated detector

Science.gov (United States)

Wilhelm, K.; Nattress, J.; Jovanovic, I.

2017-01-01

We report on the design, construction, and operation of a capture-gated neutron detector based on a heterogeneous scintillating structure comprising two scintillator types. A flat, 500 μm thick sheet composed of a mixture of lithium-6-fluoride capture agent, 6LiF, and zinc sulfide phosphor, ZnS(Ag), is wrapped around scintillating polyvinyl toluene (PVT) in a form of cylinder. The 6LiF: ZnS(Ag) sheet uses an aluminum foil backing as a support for the scintillating material and as an optical reflector, and its optical properties have been characterized independently. The composite scintillator was tested using 252Cf, DD fusion, 137Cs, and 60Co sources. The intrinsic detection efficiency for neutrons from an unmoderated 252Cf source and rejection of gammas from 137Cs were measured to be 3.6 % and 10-6, respectively. A figure of merit for pulse shape discrimination of 4.6 was achieved, and capture-gated spectroscopic analysis is demonstrated.

The Rijksherbarium, 150 years old

NARCIS (Netherlands)

NN,

1979-01-01

On March 29 and 30, 1979, the Rijksherbarium at Leiden commemorated in a modest way its foundation by King William I, 150 years ago. On the first day of the celebration a large company, including several distinguished foreign botanists, gathered in the old central building of the University for a

Annual report of STACY operation in F.Y. 1997. 280mm thickness slab core {center_dot} 10% enriched uranyl nitrate solution

Energy Technology Data Exchange (ETDEWEB)

Onodera, Seiji; Sono, Hiroki; Hirose, Hideyuki [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment] [and others

1998-06-01

Fifty-three times critical experiments (run number R0104 to R0156) with STACY in NUCEF, were performed in F.Y. 1997. During these experiments, 10% enriched uranyl nitrate solution was used as fuel, and core configuration was 280mm thickness and 1.5m height slab core tank with various rectangular solid reflectors; ordinary or borated concrete, polyethylene and so on, to measure mainly reactivity worth by changes of reflecting material and its thickness. Operation data of STACY in F.Y. 1997 are summarized in this report. (author)

A Search for Lost Planets in the Kepler Multi-Planet Systems and the Discovery of the Long-Period, Neptune-Sized Exoplanet Kepler-150 f

Science.gov (United States)

Schmitt, Joseph R.; Jenkins, Jon M.; Fischer, Debra A.

2017-01-01

The vast majority of the 4700 confirmed planets and planet candidates discovered by the Kepler space telescope were first found by the Kepler pipeline. In the pipeline, after a transit signal is found, all data points associated with those transits are removed, creating a Swiss cheese-like light curve full of holes, which is then used for subsequent transit searches. These holes could render an additional planet undetectable (or lost). We examine a sample of 114 stars with 3+ confirmed planets to see the effect that this Swiss cheesing may have. A simulation determined that the probability that a transiting planet is lost due to the transit masking is low, but non-neglible, reaching a plateau at approximately 3.3% lost in the period range of P = 400 - 500 days. We then model the transits in all quarters of each star and subtract out the transit signals, restoring the in-transit data points, and use the Kepler pipeline to search the transit-subtracted (i.e., transit-cleaned) light curves. However, the pipeline did not discover any credible new transit signals. This demonstrates the validity and robustness of the Kepler pipelines choice to use transit masking over transit subtraction. However, a follow-up visual search through all the transit-subtracted data, which allows for easier visual identification of new transits, revealed the existence of a new, Neptune-sized exoplanet. Kepler-150 f (P = 637.2 days, RP = 3.86 R earth) is confirmed using a combination of false positive probability analysis, transit duration analysis, and the planet multiplicity argument.

A SEARCH FOR LOST PLANETS IN THE KEPLER MULTI-PLANET SYSTEMS AND THE DISCOVERY OF A LONG PERIOD, NEPTUNE-SIZED EXOPLANET KEPLER-150 F.

Science.gov (United States)

Schmitt, Joseph R; Jenkins, Jon M; Fischer, Debra A

2017-04-01

The vast majority of the 4700 confirmed planets and planet candidates discovered by the Kepler space telescope were first found by the Kepler pipeline. In the pipeline, after a transit signal is found, all data points associated with those transits are removed, creating a "Swiss cheese"-like light curve full of holes, which is then used for subsequent transit searches. These holes could render an additional planet undetectable (or "lost"). We examine a sample of 114 stars with 3+ confirmed planets to see the effect that this "Swiss cheesing" may have. A simulation determined that the probability that a transiting planet is lost due to the transit masking is low, but non-neglible, reaching a plateau at ~3.3% lost in the period range of P = 400 - 500 days. We then model the transits in all quarters of each star and subtract out the transit signals, restoring the in-transit data points, and use the Kepler pipeline to search the transit-subtracted (i.e., transit-cleaned) light curves. However, the pipeline did not discover any credible new transit signals. This demonstrates the validity and robustness of the Kepler pipeline's choice to use transit masking over transit subtraction. However, a follow-up visual search through all the transit-subtracted data, which allows for easier visual identification of new transits, revealed the existence of a new, Neptune-sized exoplanet. Kepler-150 f ( P = 637.2 days, R P = 3.86 R ⊕ ) is confirmed using a combination of false positive probability analysis, transit duration analysis, and the planet multiplicity argument.

Concept Design of Trailor Ferry Service to Carry 150 Trailers Between Jacksonville, FL and Bridgeport, CT of USA

Science.gov (United States)

Sindagi, S. C.; Sandhu, B. S.

2015-04-01

With the increased load on highways, today there is a need to develop alternate ways to transport goods within the sovereignty. The use of ships to transport goods has always been the primary method of transporting goods across the seas but it can also be used to transport goods within the country. This way we can reduce the load on highways which at this point of time serve as the primary method of transportation. Worldwide very few ferries are in operation which transports 100-150 Trailers between two ports. Catching on this opportunity for design, construction and operation of vessels, a survey for possible routes in United States of America which will transport 150 Trailers has been conducted by various authorities and organizations. The challenge here is to determine the parameters of the vessel and design a fleet of vessels that could carry trailers along with their tractors within the least possible time and in with least possible freight between Jacksonville, FL and Bridgeport, CT of United States of America. The primary aim of the work presented here is to propose a design with fleet in such a way that each day 150 trailers could be loaded and unloaded at each of the two mentioned ports. An analysis of the route between the ports brought out various primary parameters like the distance, weather, different load lines to be encountered and also several size constraints that the vessel needs to adhere to, in order to ply smoothly on this route. The vessel is designed as per the Guidelines for ships operating in international waters. The economic analysis of the project was performed spanning over 20 years and the best freight was found out which would be most profitable for the company as well as be a good value for money for the customers.

Highly-efficient mid-infrared CW laser operation in a lightly-doped 3 at.% Er:SrF2 single crystal.

Science.gov (United States)

Su, Liangbi; Guo, Xinsheng; Jiang, Dapeng; Wu, Qinghui; Qin, Zhipeng; Xie, Guoqiang

2018-03-05

3 at.% Er:SrF 2 laser crystals with high optical quality were successfully grown using the temperature gradient technique (TGT). The intense mid-infrared emission was observed around 2.7 μm with excitation by a 970 nm LD. Based on the Judd-Ofelt theory, the emission cross-sections of the 4 I 13/2 - 4 I 11/2 transition were calculated by using the Fuchtbauer-Ladenburg (FL) method. Efficient continuous-wave laser operation at 2.8 µm was achieved with the lightly-doped 3 at.% Er:SrF 2 crystal pumped by a 970 nm laser diode. The laser output power reached up to 1.06 W with a maximum slope efficiency of 26%.

Fully automated synthesis system of 3'-deoxy-3'-[18F]fluorothymidine

International Nuclear Information System (INIS)

Oh, Seung Jun; Mosdzianowski, Christoph; Chi, Dae Yoon; Kim, Jung Young; Kang, Se Hun; Ryu, Jin Sook; Yeo, Jeong Seok; Moon, Dae Hyuk

2004-01-01

We developed a new fully automated method for the synthesis of 3'-deoxy-3'-[ 18 F]fluorothymidine ([ 18 F]FLT), by modifying a commercial FDG synthesizer and its disposable fluid pathway. Optimal labeling condition was that 40 mg of precursor in acetonitrile (2 mL) was heated at 150 degree sign C for 100 sec, followed by heating at 85 degree sign C for 450 sec and hydrolysis with 1 N HCl at 105 degree sign C for 300 sec. Using 3.7 GBq of [ 18 F]F - as starting activity, [ 18 F]FLT was obtained with a yield of 50.5±5.2% (n=28, decay corrected) within 60.0±5.4 min including HPLC purification. With 37.0 GBq, we obtained 48.7±5.6% (n=10). The [ 18 F]FLT showed the good stability for 6 h. This new automated synthesis procedure combines high and reproducible yields with the benefits of a disposable cassette system

Noncommutative analysis, operator theory and applications

CERN Document Server

Cipriani, Fabio; Colombo, Fabrizio; Guido, Daniele; Sabadini, Irene; Sauvageot, Jean-Luc

2016-01-01

This book illustrates several aspects of the current research activity in operator theory, operator algebras and applications in various areas of mathematics and mathematical physics. It is addressed to specialists but also to graduate students in several fields including global analysis, Schur analysis, complex analysis, C*-algebras, noncommutative geometry, operator algebras, operator theory and their applications. Contributors: F. Arici, S. Bernstein, V. Bolotnikov, J. Bourgain, P. Cerejeiras, F. Cipriani, F. Colombo, F. D'Andrea, G. Dell'Antonio, M. Elin, U. Franz, D. Guido, T. Isola, A. Kula, L.E. Labuschagne, G. Landi, W.A. Majewski, I. Sabadini, J.-L. Sauvageot, D. Shoikhet, A. Skalski, H. de Snoo, D. C. Struppa, N. Vieira, D.V. Voiculescu, and H. Woracek.

Prognostic role of microRNA-150 in various carcinomas: a meta-analysis

Directory of Open Access Journals (Sweden)

Wang W

2016-03-01

Full Text Available Wei Wang, Xinshuai Wang, Yali Zhang, Dan Wang, Hui Gao, Lijuan Wang, Shegan Gao Henan Key Laboratory of Cancer Epigenetics, Cancer Institute, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan, People’s Republic of China Objective: MicroRNA-150 (miR-150 was revealed to be an attractive prognostic biomarker in recent studies. However, the prognostic significance of miR-150 expression in cancer remains inconclusive. The aim of this study was to summarize the global predicting role of miR-150 in survival in patients with various carcinomas.Methods: Eligible studies were identified through multiple search strategies. Data were extracted from the studies by investigating the relationship between miR-150 expression and survival in patients with cancer. A meta-analysis of the hazard ratio (HR was then performed to evaluate the prognostic role of miR-150 in different tumors. Pooled HRs of miR-150 for overall survival and progression-free survival were calculated to measure the effect of miR-150 expression on prognosis.Results: This meta-analysis included nine published studies concerning various carcinomas. Our results indicate that an elevated miR-150 expression is associated with an enhanced overall survival in the digestive tract cancer subgroup (HR =0.57, 95% confidence interval [CI]: 0.37–0.90 and a poor progression-free survival in various cancers (HR =3.08, 95% CI: 2.00–4.75.Conclusion: miR-150 may have the potential to become a new useful prognostic factor to monitor cancer prognosis and progression. However, given the current insufficient relevant data, further clinical studies are needed. Keywords: microRNA-150, carcinomas, prognosis, meta-analysis

32 CFR 150.21 - Appeals by the United States.

Science.gov (United States)

2010-07-01

... 32 National Defense 1 2010-07-01 2010-07-01 false Appeals by the United States. 150.21 Section 150... the United States. (a) Restricted filing. Only a representative of the government designated by the Judge Advocate General of the respective service may file an appeal by the United States under Article...

African American Accounting Majors and the 150-hr Requirement

Science.gov (United States)

Booker, Quinton; Hill, Cecil L.; Wright, Carl

2010-01-01

The study provides information on African American accounting majors' views regarding 150-hr issues. The authors collected data from 152 students at two schools. Students at one school supported the requirement while those at the other school did not. However, students believed that the 150-hr requirement enhances the quality of certified public…

Measurement of F_2^ccbar and F_2^bbbar at High Q^2 using the H1 Vertex Detector at HERA

CERN Document Server

Aktas, A.; Anthonis, T.; Aplin, S.; Asmone, A.; Babaev, A.; Backovic, S.; Bahr, J.; Baghdasaryan, A.; Baranov, P.; Barrelet, E.; Bartel, W.; Baudrand, S.; Baumgartner, S.; Becker, J.; Beckingham, M.; Behnke, O.; Behrendt, O.; Belousov, A.; Berger, Ch.; Berger, N.; Berndt, T.; Bizot, J.C.; Bohme, J.; Boenig, M.-O.; Boudry, V.; Bracinik, J.; Brandt, G.; Brisson, V.; Broker, H.-B.; Brown, D.P.; Bruncko, D.; Busser, F.W.; Bunyatyan, A.; Buschhorn, G.; Bystritskaya, L.; Campbell, A.J.; Caron, S.; Cassol-Brunner, F.; Cerny, K.; Chekelian, V.; Contreras, J.G.; Coppens, Y.R.; Coughlan, J.A.; Cox, B.E.; Cozzika, G.; Cvach, J.; Dainton, J.B.; Dau, W.D.; Daum, K.; Delcourt, B.; Demirchyan, R.; De Roeck, A.; Desch, K.; De Wolf, E.A.; Diaconu, C.; Dingfelder, J.; Dodonov, V.; Dubak, A.; Duprel, C.; Eckerlin, Guenter; Efremenko, V.; Egli, S.; Eichler, R.; Eisele, F.; Ellerbrock, M.; Elsen, E.; Erdmann, W.; Essenov, S.; Faulkner, P.J.W.; Favart, L.; Fedotov, A.; Felst, R.; Ferencei, J.; Finke, L.; Fleischer, M.; Fleischmann, P.; Fleming, Y.H.; Flucke, G.; Flugge, G.; Fomenko, A.; Foresti, I.; Formanek, J.; Franke, G.; Frising, G.; Frisson, T.; Gabathuler, E.; Gabathuler, K.; Garutti, E.; Garvey, J.; Gayler, J.; Gerhards, R.; Gerlich, C.; Ghazaryan, Samvel; Ginzburgskaya, S.; Glazov, A.; Glushkov, I.; Goerlich, L.; Goettlich, M.; Gogitidze, N.; Gorbounov, S.; Goyon, C.; Grab, C.; Grassler, H.; Greenshaw, T.; Gregori, M.; Grindhammer, Guenter; Gwilliam, C.; Haidt, D.; Hajduk, L.; Haller, J.; Hansson, M.; Heinzelmann, G.; Henderson, R.C.W.; Henschel, H.; Henshaw, O.; Herrera, G.; Herynek, I.; Heuer, R.-D.; Hildebrandt, M.; Hiller, K.H.; Hoting, P.; Hoffmann, D.; Horisberger, R.; Hovhannisyan, A.; Ibbotson, M.; Ismail, M.; Jacquet, M.; Janauschek, L.; Janssen, X.; Jemanov, V.; Jonsson, L.; Johnson, D.P.; Jung, H.; Kant, D.; Kapichine, M.; Karlsson, M.; Katzy, J.; Keller, N.; Kenyon, I.R.; Kiesling, Christian M.; Klein, M.; Kleinwort, C.; Klimkovich, T.; Kluge, T.; Knies, G.; Knutsson, A.; Korbel, V.; Kostka, P.; Koutouev, R.; Kropivnitskaya, A.; Kruger, K.; Kuckens, J.; Landon, M.P.J.; Lange, W.; Lastovicka, T.; Laycock, P.; Lebedev, A.; Leiner, B.; Lemrani, R.; Lendermann, V.; Levonian, S.; Lindfeld, L.; Lipka, K.; List, B.; Lobodzinska, E.; Loktionova, N.; Lopez-Fernandez, R.; Lubimov, V.; Lueders, H.; Luke, D.; Lux, T.; Lytkin, L.; Makankine, A.; Malden, N.; Malinovski, E.; Mangano, S.; Marage, P.; Marks, J.; Marshall, R.; Martisikova, M.; Martyn, H.-U.; Maxeld, S.J.; Meer, D.; Mehta, A.; Meier, K.; Meyer, A.B.; Meyer, H.; Meyer, J.; Mikocki, S.; Milcewicz-Mika, I.; Milstead, D.; Mohamed, A.; Moreau, F.; Morozov, A.; Morris, J.V.; Mozer, Matthias Ulrich; Muller, K.; Murin, P.; Nagovizin, V.; Nankov, K.; Naroska, B.; Naumann, J.; Naumann, Th.; Newman, Paul R.; Niebuhr, C.; Nikiforov, A.; Nikitin, D.; Nowak, G.; Nozicka, M.; Oganezov, R.; Olivier, B.; Olsson, J.E.; Ozerov, D.; Pascaud, C.; Patel, G.D.; Peez, M.; Perez, E.; Perez-Astudillo, D.; Perieanu, A.; Petrukhin, A.; Pitzl, D.; Placakyte, R.; Poschl, R.; Portheault, B.; Povh, B.; Prideaux, P.; Raicevic, N.; Reimer, P.; Rimmer, A.; Risler, C.; Rizvi, E.; Robmann, P.; Roland, B.; Roosen, R.; Rostovtsev, A.; Rurikova, Z.; Rusakov, S.; Salvaire, F.; Sankey, D.P.C.; Sauvan, E.; Schatzel, S.; Scheins, J.; Schilling, F.-P.; Schmidt, S.; Schmitt, S.; Schmitz, C.; Schneider, M.; Schoeffel, L.; Schoning, A.; Schroder, V.; Schultz-Coulon, H.-C.; Schwanenberger, C.; Sedlak, K.; Sefkow, F.; Sheviakov, I.; Shtarkov, L.N.; Sirois, Y.; Sloan, T.; Smirnov, P.; Soloviev, Y.; South, D.; Spaskov, V.; Specka, Arnd E.; Stella, B.; Stiewe, J.; Strauch, I.; Straumann, U.; Tchoulakov, V.; Thompson, Graham; Thompson, P.D.; Tomasz, F.; Traynor, D.; Truoel, Peter; Tsipolitis, G.; Tsurin, I.; Turnau, J.; Tzamariudaki, E.; Uraev, A.; Urban, Marcel; Usik, A.; Utkin, D.; Valkar, S.; Valkarova, A.; Vallee, C.; Van Mechelen, P.; Van Remortel, N.; Vargas Trevino, A.; Vazdik, Y.; Veelken, C.; Vest, A.; Vinokurova, S.; Volchinski, V.; Vujicic, B.; Wacker, K.; Wagner, J.; Weber, G.; Weber, R.; Wegener, D.; Werner, C.; Werner, N.; Wessels, M.; Wessling, B.; Wigmore, C.; Winter, G.-G.; Wissing, Ch.; Woehrling, E.-E.; Wolf, R.; Wunsch, E.; Xella, S.; Yan, W.; Yeganov, V.; Zacek, J.; Zalesak, J.; Zhang, Z.; Zhelezov, A.; Zhokin, A.; Zimmermann, J.; Zohrabyan, H.; Zomer, F.

2004-01-01

Measurements are presented of inclusive charm and beauty cross sections in e^+p collisions at HERA for values of photon virtuality Q^2 > 150 GeV^2 and of inelasticity 0.1 < y < 0.7. The charm and beauty fractions are determined using a method based on the impact parameter, in the transverse plane, of tracks to the primary vertex, as measured by the H1 vertex detector. The data are divided into four regions in Q^2 and Bjorken x, and values for the structure functions F_2^{c\\bar{c}} and F_2^{b\\bar{b}} are obtained. The results are found to be compatible with the predictions of perturbative quantum chromodynamics.

Test facility for the development of 150-keV, multi-megawatt neutral beam systems

International Nuclear Information System (INIS)

Haughian, W.; Baker, W.R.; Biagi, L.A.; Hopkins, D.B.

1975-11-01

The next generation of CTR experiments, such as the Tokamak Fusion Test Reactor (TFTR), will require neutral-beam injection systems that produce multi-megawatt, 120-keV deuterium-beam pulses of 0.5-second duration. Since present injection systems are operating in the 10- to 40-keV range, an intensive development effort is in progress to meet a 150-keV requirement. The vacuum system and power supplies that make up a test facility to be used in the development of these injectors are described

Electrochemical studies on the redox behavior of zirconium in the LiF-NaF eutectic melt

Energy Technology Data Exchange (ETDEWEB)

Xu, Liang [School of Metallurgy, Northeastern University, Shenyang 110004 (China); Xiao, Yanping [School of Metallurgical Engineering, Anhui University of Technology, Ma' anshan 243002 (China); Zr-Hf-Ti Metallurgie B.V., Den Haag 2582 SB (Netherlands); Xu, Qian, E-mail: qianxu@shu.edu.cn [State Key Laboratory of Advanced Special Steel, Shanghai University, Shanghai 200072 (China); Sandwijk, Anthonie van [Zr-Hf-Ti Metallurgie B.V., Den Haag 2582 SB (Netherlands); Zhao, Zhuo [School of Metallurgical Engineering, Anhui University of Technology, Ma' anshan 243002 (China); Song, Qiushi; Cai, Yanqing [School of Metallurgy, Northeastern University, Shenyang 110004 (China); Yang, Yongxiang [School of Metallurgical Engineering, Anhui University of Technology, Ma' anshan 243002 (China); Department of Materials Science and Engineering, Delft University of Technology, 2628 CD Delft (Netherlands)

2017-05-15

In the present paper, a detailed study of the redox behavior of zirconium in the eutectic LiF-NaF system was carried out on an inert molybdenum electrode at 750 °C. Several transient electrochemical methods were used such as cyclic voltammetry, square wave voltammetry, chronopotentiometry, and open circuit voltammetry. The reduction of Zr (IV) was found to follow a two-step mechanism of Zr (IV)/Zr (II) and Zr (II)/Zr at the potentials of about −1.10 and −1.50 V versus Pt, respectively. The theoretical evaluations of the number of transferred electrons according to both cyclic voltammetry and square wave voltammetry further confirmed the Zr reduction mechanism. The estimations of Zr (IV) diffusion coefficient in the LiF-NaF eutectic melt at 750 °C through cyclic voltammetry and chronopotentiometry are in fair agreement, as to be approximately 1.13E-5 and 2.42E-5 cm{sup 2}/s, respectively. - Highlights: •The redox mechanism of zirconium in a fluoride salt system was investigated. •A multi-step redox process of Zr was found with various electrochemical methods. •Perspectives on zirconium electro-refining process were proposed.

R-parity violation in F-theory

Energy Technology Data Exchange (ETDEWEB)

Romão, Miguel Crispim [Physics and Astronomy, University of Southampton,SO17 1BJ Southampton (United Kingdom); Karozas, Athanasios [Physics Department, Theory Division, Ioannina University,GR-45110 Ioannina (Greece); King, Stephen F. [Physics and Astronomy, University of Southampton,SO17 1BJ Southampton (United Kingdom); Leontaris, George K. [Physics Department, Theory Division, Ioannina University,GR-45110 Ioannina (Greece); Meadowcroft, Andrew K. [Physics and Astronomy, University of Southampton,SO17 1BJ Southampton (United Kingdom)

2016-11-14

We discuss R-parity violation (RPV) in semi-local and local F-theory constructions. We first present a detailed analysis of all possible combinations of RPV operators arising from semi-local F-theory spectral cover constructions, assuming an SU(5) GUT. We provide a classification of all possible allowed combinations of RPV operators originating from operators of the form 10⋅5̄⋅5̄, including the effect of U(1) fluxes with global restrictions. We then relax the global constraints and perform explicit computations of the bottom/tau and RPV Yukawa couplings, at an SO(12) local point of enhancement in the presence of general fluxes subject only to local flux restrictions. We compare our results to the experimental limits on each allowed RPV operator, and show that operators such as LLe{sup c}, LQd{sup c} and u{sup c}d{sup c}d{sup c} may be present separately within current bounds, possibly on the edge of observability, suggesting lepton number violation or neutron-antineutron oscillations could constrain F-theory models.

Recurrent surgical site infection of the spine diagnosed by dual 18F-NaF-bone PET/CT with early-phase scan

International Nuclear Information System (INIS)

Shim, Jai-Joon; Lee, Jeong Won; Jeon, Min Hyok; Lee, Sang Mi

2016-01-01

We report a case of a 31-year-old man who showed recurrently elevated level of the serum inflammatory marker C-reactive protein (CRP) after spinal operation. He underwent 18 F-flurodeoxyglucose ( 18 F-FDG) positron emission tomography/computed tomography (PET/CT) and dual 18 F-sodium-fluoride ( 18 F-NaF) PET/CT with an additional early-phase scan to find a hidden inflammation focus. Only mildly increased 18 F-FDG was found at the surgical site of T11 spine on 18 F-FDG PET/CT. In contrast, dual 18 F-NaF bone PET/CT with early-phase scan demonstrated focal active inflammation at the surgical site of T11 spine. After a revision operation of the T11 spine, serum CRP level decreased to the normal range without any symptom or sign of inflammation. Inflammatory focus in the surgical site of the spine can be detected with using dual 18 F-NaF bone PET/CT scan with early-phase scan. (orig.)

Effect of high-energy electron irradiation in an electron microscope column on fluorides of alkaline earth elements (CaF2, SrF2, and BaF2)

International Nuclear Information System (INIS)

Nikolaichik, V. I.; Sobolev, B. P.; Zaporozhets, M. A.; Avilov, A. S.

2012-01-01

The effect of high-energy (150 eV) electron irradiation in an electron microscope column on crystals of fluorides of alkaline earth elements CaF 2 , SrF 2 , and BaF 2 is studied. During structural investigations by electron diffraction and electron microscopy, the electron irradiation causes chemical changes in MF 2 crystals such as the desorption of fluorine and the accumulation of oxygen in the irradiated area with the formation of oxide MO. The fluorine desorption rate increases significantly when the electron-beam density exceeds the threshold value of ∼2 × 10 3 pA/cm 2 ). In BaF 2 samples, the transformation of BaO into Ba(OH) 2 was observed when irradiation stopped. The renewal of irradiation is accompanied by the inverse transformation of Ba(OH) 2 into BaO. In the initial stage of irradiation of all MF 2 compounds, the oxide phase is in the single-crystal state with a lattice highly matched with the MF 2 matrix. When the irradiation dose is increased, the oxide phase passes to the polycrystalline phase. Gaseous products of MF 2 destruction (in the form of bubbles several nanometers in diameter) form a rectangular array with a period of ∼20 nm in the sample.

MIV-150-containing intravaginal rings protect macaque vaginal explants against SHIV-RT infection.

Science.gov (United States)

Ouattara, Louise A; Barnable, Patrick; Mawson, Paul; Seidor, Samantha; Zydowsky, Thomas M; Kizima, Larisa; Rodriguez, Aixa; Fernández-Romero, José A; Cooney, Michael L; Roberts, Kevin D; Gettie, Agegnehu; Blanchard, James; Robbiani, Melissa; Teleshova, Natalia

2014-05-01

Recent studies demonstrated that intravaginal rings (IVRs) containing 100 mg of the nonnucleoside reverse transcriptase inhibitor (NNRTI) MIV-150 significantly protect macaques against a chimeric simian-human immunodeficiency virus that expresses the HIV-1 HxB2 reverse transcriptase (SHIV-RT) when present before and after vaginal challenge. The objectives of this study were to (i) evaluate the pharmacodynamics (PD) of MIV-150 in vaginal fluids (VF) and in ectocervical and vaginal tissues following 100-mg MIV-150 IVR exposure and to (ii) gain more insight whether pharmacokinetics (PK) of MIV-150 can predict PD. MIV-150 in VF collected at 1 day and 14 days post-MIV-150 IVR insertion inhibited ex vivo SHIV-RT infection in vaginal biopsy specimens from untreated animals (not carrying IVRs) in a dose-dependent manner. Previous PK studies demonstrated a significant increase of ectocervical and vaginal tissue MIV-150 concentrations 14 days versus 1 day post-IVR insertion, with the highest increase in vaginal tissue. Therefore, we tested PD of MIV-150 in tissues 14 days post-MIV-150 IVR insertion. Ex vivo SHIV-RT infection of vaginal, but not ectocervical, tissues collected 14 days post-MIV-150 IVR insertion was significantly inhibited compared to infection at the baseline (prior to MIV-150 IVR exposure). No changes in vaginal and ectocervical tissue infection were observed after placebo IVR exposure. Overall, these data underscore the use of the ex vivo macaque explant challenge models to evaluate tissue and VF PK/PD of candidate microbicides before in vivo animal efficacy studies. The data support further development of MIV-150-containing IVRs.

Zantac® 150 y ranitidina de producción nacional: liberación in vitro ZantacÒ150 and ranitidine of national production: in vitro release

Directory of Open Access Journals (Sweden)

Lisette Martínez Miranda

2004-08-01

Full Text Available Dentro del proceso global de la liberación de un fármaco, la disolución constituye el paso más importante pues se encuentra íntimamente relacionada con los procesos de absorción, determinantes en la biodisponibilidad de un medicamento administrado por vía oral. En el presente trabajo se realizaron los perfiles de disolución de 3 lotes de Zantac® (GlaxoWellcome, medicamento líder del principio activo ranitidina (DCI y de 3 lotes de ranitidina 150 mg de producción nacional. Para el estudio de disolución se utilizó el método descrito en la USP 23. Los datos de porcentaje de principio activo liberado contra tiempo fueron sometidos a un estudio de ajuste a 4 modelos comunes a perfiles de disolución mediante el programa CurveExpert. Todos los lotes estudiados cumplen con los criterios de la Food and Drug Administration (FDA para los estudios de bioequivalencia in vitro.Dissolution is the most important step in the global release process of a drug , since it is closely related to the absorption processes, which are determinant in the bioavailability of a drug administered by oral route. The dissolution profiles of 3 batches of Zantac® (Glaxo Wellcome, a leading drug of the ranitidine active principle (DCI, and of 3 batches of ranitidine 150 mg of national production were performed. The method described in the USP 23 was used for the dissolution test. The percentage data of the active principle released against time were subjected to a study of adjustment of 4 models to common disssolution profiles by the CurveExpert program. All the studied batches fulfilled the criteria of the Food and Drug Administration (FDA for the in vitro bioequivalence studies.

Diffusion and the dynamics of displacive phase transitions in cryolite (Na3AlF6) and chiolite (Na5Al3F14): Multi-nuclear NMR studies

Science.gov (United States)

Spearing, Dane R.; Stebbins, Jonathan F.; Farnan, Ian

1994-10-01

Cryolite is a mixed-cation perovskite (Na2(NaAl)F6) which undergoes a monoclinic to orthorhombic displacive phase transition at ˜550° C. Chiolite (Na5Al3F14) is associated with cryolite in natural deposits, and consists of sheets of corner sharing [AlF6] octahedra interlayered with edge-sharing [NaF6] octahedra. Multi-nuclear NMR line shape and relaxation time (T1) studies were performed on cryolite and chiolite in order to gain a better understanding of the atomic motions associated with the phase transition in cryolite, and Na diffusion in cryolite and chiolite. 27Al, 23Na, and 19F static NMR spectra and T1's in cryolite suggest that oscillatory motions of the [AlF6] octahedra among four micro-twin and anti-phase domains in α-cryolite begin at least 150° C below the transition temperature and persist above it. Variable temperature 23Na MAS NMR further indicates diffusional exchange at a rate of at least 13 kHz between the Na sites by the time the transition temperature is reached. 27Al and 23Na T1's show the same behavior with increasing temperature, indicating the same relaxation mechanisms are responsible for both. The first order nature of the cryolite transition is apparent as a jump in the 23Na and 27Al T1's. Above the transition temperature, the T1's decrease slightly indicating that the motions responsible for the drop in T1, are still present above the transition, further supporting the dynamic nature of the high temperature phase of cryolite. Chiolite 23Na static spectra decrease in linewidth with increasing temperature, indicating increased Na diffusion, which is interpreted as occurring within the [NaF6] sheets in the chiolite structure, but not between the two different Na sites. 27Al and 23Na T1's show similar behavior as in cryolite, but there is no discontinuity due to a phase transition. 19F T1's are constant from room temperature to 150° C indicating no oscillatory motion of the [AlF6] octahedra in chiolite.

21 CFR 150.161 - Artificially sweetened fruit preserves and jams.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Artificially sweetened fruit preserves and jams. 150.161 Section 150.161 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN... karaya, gum tragacanth, algin (sodium alginate), sodium carboxymethylcellulose (cellulose gum...

Oncology pharma costs to exceed $150 billion by 2020.

Science.gov (United States)

2016-10-01

Worldwide costs of oncology drugs will rise above $150 billion by 2020, according to a report by the IMS Institute for Healthcare Informatics. Many factors are in play, according to IMS, including the new wave of expensive immunotherapies. Pembrolizumab (Keytruda), priced at $150,000 per year per patient, and nivolumab (Opdivo), priced at $165,000, may be harbingers of the market for cancer immunotherapies.

Properties of singular integral operators

Indian Academy of Sciences (India)

Amit Samanta

2018-03-22

Mar 22, 2018 ... the Toeplitz operator. Tφ on H2 is defined by Tφ( f ) = P(φf ) for all f ∈ H2. The following mentioned properties of the Topelitz operator are well-known and can be found in Chapter 3 and. Chapter 1 of [3]. •Tφ = spectral radius of Tφ =φ ∞. • The commutant of the unilateral shift acting on H2 is Tφ such that φ ...

Antimicrobial activity of ozone and NaF-chlorhexidine on early childhood caries

Directory of Open Access Journals (Sweden)

Marcos XIMENES

Full Text Available Abstract An early childhood carie (ECC is an extremely destructive form of tooth decay. The aim of this study was to investigate the action of ozone (O3, and the association of sodium fluoride (NaF with chlorhexidine (CHX on bacteria related to ECC. Overnight culture of the bacteria was performed. On exponential phase the suspension was adjusted (101-108 CFU/mL. A drop (10μL of each concentration of bacteria was applied on sheep blood agar plates and treated with O3 (2, 20, 200, and 2,000 ppm; after 18 hours, recovery analysis of CFU verified the reduction of bacterial activity. For NaF-CHX, sterile 96-well plates were prepared and divided into groups: G1 (150 µL TSB; G2 (20 µL of bacteria + 25 µL CHX + 25 µL NaF; and G3 (150 µL TSB + 20 µL of bacteria + 50 µL water. The plates were verified by analysis of the optical density (0, 12, 14, 16, and 18 hours. The data from O3 test were submitted to ANOVA and Tukey’s test (p 3log10 (99.9% for all bacteria (ozone ≥ 20ppm, while the combination of NaF-CHX was more effective (p < 0.001 compared to each substance tested alone and the control group. The antimicrobial agents tested were able to inhibit all bacteria tested; O3 seemed to be a good alternative for controlling progression of carious lesions, while the association of NaF-CHX showed to be a good antimicrobial with easy and inexpensive application.

33 CFR 110.150 - Block Island Sound, N.Y.

Science.gov (United States)

2010-07-01

... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Block Island Sound, N.Y. 110.150... ANCHORAGE REGULATIONS Anchorage Grounds § 110.150 Block Island Sound, N.Y. (a) The anchorage ground. A 3/4... following coordinates: latitude 41°06′12″ N., longitude 72°00′05″ W., latitude 41°07′40″ N., longitude 72°01...

10 CFR 150.19 - Submission to Commission of tritium reports.

Science.gov (United States)

2010-01-01

... 10 Energy 2 2010-01-01 2010-01-01 false Submission to Commission of tritium reports. 150.19... Agreement States § 150.19 Submission to Commission of tritium reports. (a)-(b) [Reserved] (c) Except as... authorized to possess tritium shall report promptly to the appropriate NRC Regional Office as shown in...

46 CFR Appendix II to Part 150 - Explanation of Figure 1

Science.gov (United States)

2010-10-01

... COMPATIBILITY OF CARGOES Pt. 150, App. II Appendix II to Part 150—Explanation of Figure 1 Definition of a..., aromatic hydrocarbons or paraffins. Others will form hazardous combinations with many groups: For example...

Free electron laser facilities employing a 150-MeV linac injector for Saga synchrotron light source

International Nuclear Information System (INIS)

Tomimasu, T.; Yasumoto, M.; Ochiai, Y.; Ishibashi, M.; Murayama, T.

1999-01-01

Free electron laser (FEL) facilities as the FELI FEL Facility are proposed, for which a 150-MeV linac type injector for a Saga synchrotron light source (SLS) is employed in FEL mode. The linac has two operating modes; short macropulse mode a 1 μs at 150 MeV for injection to a 1 - 1.3-GeV third generation type storage ring and long macropulse mode of 12 μs at 100 MeV for four FEL Facilities. The macropulse beam consists of a train of several ps, 0.6 nC microbunches (peak current 100 A) repeating at 89.25 MHz. We are aiming to supply high power level photon beams covering an attractive wavelength range from 0.05 nm (25 keV) to 200 μm (0.006 eV) for scientific researches, bio-medical and industrial applications, using the Saga third generation type SLS with a superconducting wiggler and the proposed four FEL Facilities. (author)

Rearing and gamma radiation effects on mature pupae of pink bollworm and their F1 progeny

International Nuclear Information System (INIS)

Qureshi, Z.A.; Ahmed, N.; Hussain, T.

1993-01-01

Pink bollworm larvae were successfully reared in captivity on a casein wheat germ diet. The substitution of casein with soyflour, corn-cob grit and wheat germ, and casein for peanut flour, resulted in delayed development, reduced pupal recovery and fecundity of the adult moths. This reduction was more drastic in corn-cob grit and peanut flour diets. The irradiation of mature pupae at 50-200 Gy resulted in decreased adult emergence with increased gamma radiation doses, and more deformed moths were recorded at a dose of 200 Gy. Adults following irradiation of mature pupae when crossed with untreated males or females or treated individuals crossed to treated exhibited reduced fecundity and fertility with the increasing doses. This reduction was more pronounced when treated males were crossed with treated females. Females were relatively more sensitive to gamma radiation, as a reduced number of eggs was obtained when treated females were crossed with untreated males. At 200 Gy, no F 1 progeny were obtained from any cross involving treated parents. The fecundity and fertility were reduced significantly when F 1 males or F 1 females from male parents irradiated as mature pupae were mated with untreated insects at both 100 and 150 Gy. However, inherited sterility was more pronounced when F 1 males were crossed with untreated females than when F 1 females were crossed with untreated males. Similarly reduced fecundity and fertility in F 1 progeny from female parents irradiated as mature pupae, both at 100 and 150 Gy, were also recorded in crosses as described for male F 1 progeny. The fecundity and fertility were the lowest in F 1 progeny of both male and female parents irradiated as mature pupae when compared with the F 1 progeny of male or female irradiated parents separately. (author). 28 refs, 7 tabs

2011 Special Operations Forces Industry Conference

Science.gov (United States)

2011-05-19

Fixed Operators Wateen : First nationwide WiMAX 4G deployment in the world (Nov 2008) UNCLASSIFIED UNCLASSIFIED 13 Mobile WiMax Phones Samsung (Korea...Currently 582 operators in 150 countries • $1.2 B investment planned for 2011 (China, US, Taiwan, Korea, Malaysia ) • Coverage of 823 mil persons end of 2010...Steam! • January 2010 – First public LTE network operational in Stockholm/Oslo – Uses Samsung devices, Ericsson network core – 50 Mbps download, 20

Herpes simplex virus thymidine kinase imaging in mice with (1-(2'-deoxy-2'-[{sup 18}F]fluoro-1-{beta}-D-arabinofuranosyl)-5-iodouracil) and metabolite (1-(2'-deoxy-2'-[{sup 18}F]fluoro-1-{beta}-D-arabinofuranosyl)-5-uracil)

Energy Technology Data Exchange (ETDEWEB)

Nimmagadda, Sridhar; Lawhorn-Crews, Jawana M.; Shields, Anthony F. [Wayne State University, Karmanos Cancer Institute, Detroit, MI (United States); Wayne State University, Department of Medicine, Detroit, MI (United States); Mangner, Thomas J. [Wayne State University, Karmanos Cancer Institute, Detroit, MI (United States); Wayne State University, Department of Radiology, Detroit, MI (United States); Haberkorn, Uwe [University of Heidelberg, Department of Nuclear Medicine, Heidelberg (Germany)

2009-12-15

FIAU, (1-(2{sup '}-deoxy-2{sup '}-fluoro-1-{beta}-D-arabinofuranosyl)-5-iodouracil) has been used as a substrate for herpes simplex virus thymidine kinases (HSV-TK and HSV-tk, for protein and gene expression, respectively) and other bacterial and viral thymidine kinases for noninvasive imaging applications. Previous studies have reported the formation of a de-iodinated metabolite of {sup 18}F-FIAU. This study reports the dynamic tumor uptake, biodistribution, and metabolite contribution to the activity of {sup 18}F-FIAU seen in HSV-tk gene expressing tumors and compares the distribution properties with its de-iodinated metabolite {sup 18}F-FAU. CD-1 nu/nu mice with subcutaneous MH3924A and MH3924A-stb-tk+ xenografts on opposite flanks were used for the biodistribution and imaging studies. Mice were injected IV with either {sup 18}F-FIAU or {sup 18}F-FAU. Mice underwent dynamic imaging with each tracer for 65 min followed by additional static imaging up to 150 min post-injection for some animals. Animals were sacrificed at 60 or 150 min post-injection. Samples of blood and tissue were collected for biodistribution and metabolite analysis. Regions of interest were drawn over the images obtained from both tumors to calculate the time-activity curves. Biodistribution and imaging studies showed the highest uptake of {sup 18}F-FIAU in the MH3924A-stb-tk+ tumors. Dynamic imaging studies revealed a continuous accumulation of {sup 18}F-FIAU in HSV-TK expressing tumors over 60 min. The mean biodistribution values (SUV {+-} SE) for MH3924A-stb-tk+ were 2.07 {+-} 0.40 and 6.15 {+-} 1.58 and that of MH3924A tumors were 0.19 {+-} 0.07 and 0.47 {+-} 0.06 at 60 and 150 min, respectively. In {sup 18}F-FIAU injected mice, at 60 min nearly 63% of blood activity was present as its metabolite {sup 18}F-FAU. Imaging and biodistribution studies with {sup 18}F-FAU demonstrated no specific accumulation in MH3924A-stb-tk+ tumors and SUVs for both the tumors were similar to those

21 CFR 801.150 - Medical devices; processing, labeling, or repacking.

Science.gov (United States)

2010-04-01

... originally processed or packed, shall be exempt, during the time of introduction into and movement in... otherwise accounting for the number of units in each shipment to insure that the number of units shipped is... repacking. 801.150 Section 801.150 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND...

42 CFR 457.150 - CMS review of State plan material.

Science.gov (United States)

2010-10-01

... 42 Public Health 4 2010-10-01 2010-10-01 false CMS review of State plan material. 457.150 Section... Introduction; State Plans for Child Health Insurance Programs and Outreach Strategies § 457.150 CMS review of State plan material. (a) Basis for action. CMS reviews each State plan and plan amendment to determine...

14 CFR Appendix A to Part 150 - Noise Exposure Maps

Science.gov (United States)

2010-01-01

... 150 under § 150.11. For purposes of this part, the tolerances allowed for general purpose, type 2... Y Y Y Y Recreational Outdoor sports arenas and spectator sports Y Y(5) Y(5) N N N Outdoor music... average-daily-basis, the number of aircraft, by type of aircraft, which utilize each flight track, in both...

Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua

OpenAIRE

Di Stefano, Giuseppe

2016-01-01

Reseña de Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua, Commissione per i testi di lingua (Collezione di opere inedite o rare, 169), Bologna, 2012, x + 320 pp. ISBN: 9788898096152.

Plasticity of 150-loop in influenza neuraminidase explored by Hamiltonian replica exchange molecular dynamics simulations.

Directory of Open Access Journals (Sweden)

Nanyu Han

Full Text Available Neuraminidase (NA of influenza is a key target for antiviral inhibitors, and the 150-cavity in group-1 NA provides new insight in treating this disease. However, NA of 2009 pandemic influenza (09N1 was found lacking this cavity in a crystal structure. To address the issue of flexibility of the 150-loop, Hamiltonian replica exchange molecular dynamics simulations were performed on different groups of NAs. Free energy landscape calculated based on the volume of 150-cavity indicates that 09N1 prefers open forms of 150-loop. The turn A (residues 147-150 of the 150-loop is discovered as the most dynamical motif which induces the inter-conversion of this loop among different conformations. In the turn A, the backbone dynamic of residue 149 is highly related with the shape of 150-loop, thus can function as a marker for the conformation of 150-loop. As a contrast, the closed conformation of 150-loop is more energetically favorable in N2, one of group-2 NAs. The D147-H150 salt bridge is found having no correlation with the conformation of 150-loop. Instead the intimate salt bridge interaction between the 150 and 430 loops in N2 variant contributes the stabilizing factor for the closed form of 150-loop. The clustering analysis elaborates the structural plasticity of the loop. This enhanced sampling simulation provides more information in further structural-based drug discovery on influenza virus.

26 CFR 1.150-1 - Definitions.

Science.gov (United States)

2010-04-01

... is the purpose investment). (B) Recycling of certain payments under purpose investments. A conduit... for all purposes of sections 103 and 141 through 150. (2) Effective date—(i) In general. Except as... obligor on a purpose investment (as defined in § 1.148-1). For example, if an issuer invests proceeds in a...

Pursuit of excellence in F/H operator performance

International Nuclear Information System (INIS)

Keelan, B.; Curle, B.

1996-01-01

Performance of any fuel handling system is heavily dependent on the performance of the system operators. Sadly, this topic often receives little attention until incidents occur. Darlington has taken a proactive approach designed to reach and maintain excellent operator performance. Expectations and Standards are generated and published. A detailed, goal-oriented, auditable training program, which includes hands-on training modules, ensures operators reach the standards before qualifications are granted. Refresher courses maintain current skills. A depersonalized, computerized reporting system ensures training and standards are updated to match current situations. (author). 1 fig

Pursuit of excellence in F/H operator performance

Energy Technology Data Exchange (ETDEWEB)

Keelan, B; Curle, B [Ontario Hydro, Bowmanville (Canada). Darlington Nuclear Generating Station

1997-12-31

Performance of any fuel handling system is heavily dependent on the performance of the system operators. Sadly, this topic often receives little attention until incidents occur. Darlington has taken a proactive approach designed to reach and maintain excellent operator performance. Expectations and Standards are generated and published. A detailed, goal-oriented, auditable training program, which includes hands-on training modules, ensures operators reach the standards before qualifications are granted. Refresher courses maintain current skills. A depersonalized, computerized reporting system ensures training and standards are updated to match current situations. (author). 1 fig.

miR-150-Mediated Foxo1 Regulation Programs CD8+ T Cell Differentiation.

Science.gov (United States)

Ban, Young Ho; Oh, Se-Chan; Seo, Sang-Hwan; Kim, Seok-Min; Choi, In-Pyo; Greenberg, Philip D; Chang, Jun; Kim, Tae-Don; Ha, Sang-Jun

2017-09-12

MicroRNA (miR)-150 is a developmental regulator of several immune-cell types, but its role in CD8 + T cells is largely unexplored. Here, we show that miR-150 regulates the generation of memory CD8 + T cells. After acute virus infection, miR-150 knockout (KO) mice exhibited an accelerated differentiation of CD8 + T cells into memory cells and improved production of effector cytokines. Additionally, miR-150 KO CD8 + T cells displayed an enhanced recall response and improved protection against infections with another virus and bacteria. We found that forkhead box O1 (Foxo1) and T cell-specific transcription factor 1 (TCF1) are upregulated during the early activation phase in miR-150 KO CD8 + T cells and that miR-150 directly targets and suppresses Foxo1. These results suggest that miR-150-mediated suppression of Foxo1 regulates the balance between effector and memory cell differentiation, which might aid in the development of improved vaccines and T cell therapeutics. Copyright © 2017 The Authors. Published by Elsevier Inc. All rights reserved.

150 years of electrical engineering. A review and future prospects for power plant construction; 150 Jahre Elektrotechnik. Rueckblick und Vision im Kraftwerksbau

Energy Technology Data Exchange (ETDEWEB)

Boehm, H. [Siemens AG Unternehmensbereich KWU, Erlangen (Germany). Bereich Energieerzeugung

1997-12-01

The development of power plant construction both in the last 150 years and also relative to the deduced major trends for the future is illustrated by the important milestones. In this respect, the important role of modern power stations is very prominent in ensuring enduring economic development. (orig.) [Deutsch] Anhand von wichtigen Meilensteinen wird die Entwicklung im Kraftwerksbau sowohl in den letzten 150 Jahren als auch entsprechend den sich abzeichnenden grossen Trends fuer die Zukunft beleuchtet. Dabei steht die wichtige Rolle moderner Kraftwerke fuer eine nachhaltige Entwicklung im Vordergrund. (orig.)

A calibration-free ammonia breath sensor using a quantum cascade laser with WMS 2f/1f

KAUST Repository

Owen, Kyle; Farooq, Aamir

2013-01-01

modulation spectroscopy with second harmonic normalized by the first harmonic (WMS 2f/1f) is a sensitive technique used in the development of calibration-free sensors. An ammonia gas sensor is designed and developed that uses a quantum cascade laser operating

Simple model for deriving sdg interacting boson model Hamiltonians: 150Nd example

Science.gov (United States)

Devi, Y. D.; Kota, V. K. B.

1993-07-01

A simple and yet useful model for deriving sdg interacting boson model (IBM) Hamiltonians is to assume that single-boson energies derive from identical particle (pp and nn) interactions and proton, neutron single-particle energies, and that the two-body matrix elements for bosons derive from pn interaction, with an IBM-2 to IBM-1 projection of the resulting p-n sdg IBM Hamiltonian. The applicability of this model in generating sdg IBM Hamiltonians is demonstrated, using a single-j-shell Otsuka-Arima-Iachello mapping of the quadrupole and hexadecupole operators in proton and neutron spaces separately and constructing a quadrupole-quadrupole plus hexadecupole-hexadecupole Hamiltonian in the analysis of the spectra, B(E2)'s, and E4 strength distribution in the example of 150Nd.

Simple model for deriving sdg interacting boson model Hamiltonians: 150Nd example

International Nuclear Information System (INIS)

Devi, Y.D.; Kota, V.K.B.

1993-01-01

A simple and yet useful model for deriving sdg interacting boson model (IBM) Hamiltonians is to assume that single-boson energies derive from identical particle (pp and nn) interactions and proton, neutron single-particle energies, and that the two-body matrix elements for bosons derive from pn interaction, with an IBM-2 to IBM-1 projection of the resulting p-n sdg IBM Hamiltonian. The applicability of this model in generating sdg IBM Hamiltonians is demonstrated, using a single-j-shell Otsuka-Arima-Iachello mapping of the quadrupole and hexadecupole operators in proton and neutron spaces separately and constructing a quadrupole-quadrupole plus hexadecupole-hexadecupole Hamiltonian in the analysis of the spectra, B(E2)'s, and E4 strength distribution in the example of 150 Nd

Fluoride ion donor properties of cis-OsO(2)F(4): synthesis, raman spectroscopic study, and X-ray crystal structure of [OsO(2)F(3)][Sb(2)F(11)].

Science.gov (United States)

Hughes, Michael J; Mercier, Hélène P A; Schrobilgen, Gary J

2010-01-04

The salt, [OsO(2)F(3)][Sb(2)F(11)], has been synthesized by dissolution of cis-OsO(2)F(4) in liquid SbF(5), followed by removal of excess SbF(5) at 0 degrees C to yield orange, crystalline [OsO(2)F(3)][Sb(2)F(11)]. The X-ray crystal structure (-173 degrees C) consists of an OsO(2)F(3)(+) cation fluorine bridged to an Sb(2)F(11)(-) anion. The light atoms of OsO(2)F(3)(+) and the bridging fluorine atom form a distorted octahedron around osmium in which the osmium atom is displaced from its center toward an oxygen atom and away from the trans-fluorine bridge atom. As in other transition metal dioxofluorides, the oxygen ligands are cis to one another and the fluorine bridge atom is trans to an oxygen ligand and cis to the remaining oxygen ligand. The Raman spectrum (-150 degrees C) of solid [OsO(2)F(3)][Sb(2)F(11)] was assigned on the basis of the ion pair observed in the low-temperature crystal structure. Under dynamic vacuum, [OsO(2)F(3)][Sb(2)F(11)] loses SbF(5), yielding the known [mu-F(OsO(2)F(3))(2)][Sb(2)F(11)] salt with no evidence for [OsO(2)F(3)][SbF(6)] formation. Attempts to synthesize [OsO(2)F(3)][SbF(6)] by the reaction of [OsO(2)F(3)][Sb(2)F(11)] with an equimolar amount of cis-OsO(2)F(4) or by a 1:1 stoichiometric reaction of cis-OsO(2)F(4) with SbF(5) in anhydrous HF yielded only [mu-F(OsO(2)F(3))(2)][Sb(2)F(11)]. Quantum-chemical calculations at the SVWN and B3LYP levels of theory and natural bond orbital analyses were used to calculate the gas-phase geometries, vibrational frequencies, natural population analysis charges, bond orders, and valencies of OsO(2)F(3)(+), [OsO(2)F(3)][Sb(2)F(11)], [OsO(2)F(3)][SbF(6)], and Sb(2)F(11)(-). The relative thermochemical stabilities of [OsO(2)F(3)][SbF(6)], [OsO(2)F(3)][Sb(2)F(11)], [OsO(2)F(3)][AsF(6)], [mu-F(OsO(2)F(3))(2)][SbF(6)], [mu-F(OsO(2)F(3))(2)][Sb(2)F(11)], and [mu-F(OsO(2)F(3))(2)][AsF(6)] were assessed using the appropriate Born-Haber cycles to account for the preference for [mu-F(OsO(2)F(3

Neutron flux stabilization in the NG-150 neutron generators

International Nuclear Information System (INIS)

Kuz'min, L.E.; Makarov, S.A.; Pronman, I.M.

1986-01-01

Problem of metal tritium target lifetime increase and neutron flux stabilization in the NG-150 neutron generators is studied. Possibility on neutron flux stabilization using the mass analyzer for low-angle (4 deg and 41 deg) mass separation of a beam in thre components, which fall on a target simultaneously, is confirmed experimentally. Basic generator parameters are: accelerating voltage of 150 kV, total beam current on a target of 1.5 mA, beam current density of 0.3-1.6 mA/cm 2 , beam diameter of 8 mm. The initial neutron flux on the targets of 0.73 mg/cm 2 thick constituted 1.1x10 11 ssup(-1). The neutron flux monitoring was accomplished from recoil proton recording by a plastic scintillator. Flux decrease by more than 5% served as a signel for measuring mass analyzer magnetic field providing beam displacement on a target and restoration of the given flux. The NG-150 generator neutron flux stabilization was attained during 2h

Completion of the Kernel of the Differentiation Operator

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Anatoly N. Morozov

2017-01-01

Full Text Available When investigating piecewise polynomial approximations in spaces \\(L_p, \\; 0~<~p~<~1,\\ the author considered the spreading of k-th derivative (of the operator from Sobolev spaces \\(W_1 ^ k\\ on spaces that are, in a sense, their successors with a low index less than one. In this article, we continue the study of the properties acquired by the differentiation operator \\(\\Lambda\\ with spreading beyond the space \\(W_1^1\\ $$\\Lambda~:~W_1^1~\\mapsto~L_1,\\; \\Lambda f = f^{\\;'} $$.The study is conducted by introducing the family of spaces \\(Y_p^1, \\; 0

operator: $$ \\bigcup_{n=1}^{m} \\Lambda (f_n = \\Lambda (\\bigcup_{n=1}^{m} f_n.$$Here, for a function \\(f_n\\ defined on \\([x_{n-1}; x_n], \\; a~=~x_0 < x_1 < \\cdots f_n\\ was defined. One of the most important characteristics of a linear operator is the composition of the kernel.During the spreading of the differentiation operator from the space \\( C ^ 1 \\ on the space \\( W_p ^ 1 \\ the kernel does not change. In the article, it is constructively shown that jump functions and singular functions \\(f\\ belong to all spaces \\( Y_p ^ 1 \\ and \\(\\Lambda f = 0.\\ Consequently, the space of the functions of the bounded variation \\(H_1 ^ 1 \\ is contained in each \\( Y_p ^ 1 ,\\ and the differentiation operator on \\(H_1^1\\ satisfies the relation \\(\\Lambda f = f^{\\; '}.\\Also, we come to the conclusion that every function from the added part of the kernel can be logically named singular.

75 FR 34347 - Airworthiness Directives; Honeywell International Inc. Auxiliary Power Unit Models GTCP36-150(R...

Science.gov (United States)

2010-06-17

... Airworthiness Directives; Honeywell International Inc. Auxiliary Power Unit Models GTCP36-150(R) and GTCP36-150...) models GTCP36- 150(R) and GTCP36-150(RR). This AD requires inspecting the fuel control unit (FCU...-150(R) and GTCP36-150(RR). We published the proposed AD in the Federal Register on December 23, 2009...

Spin structure of exchange biased heterostructures. Fe/MnF{sub 2} and Fe/FeF{sub 2}

Energy Technology Data Exchange (ETDEWEB)

Sahoo, B

2006-12-18

In this work, the {sup 57}Fe probe layer technique is used in order to investigate the depth- and temperature-dependent Fe-layer spin structure of exchange biased Fe/MnF{sub 2} and Fe/FeF{sub 2} (pseudo-twinned) antiferromagnetic (AFM) systems by conversion electron Moessbauer spectroscopy (CEMS) and nuclear resonant scattering (NRS) of synchrotron radiation. Two kinds of samples with a 10 A {sup 57}Fe probe layer directly at or 35 A away from the interface, labeled as interface and center sample, respectively, were studied in this work. The results obtained by CEMS for Fe/MnF{sub 2} suggests that, at 80 K, i.e., above T{sub N}=67 K of MnF{sub 2}, the remanent state Fe-layer spin structure of the two studied samples are slightly different due to their different microstructure. In the temperature range from 300 K to 80 K, the Fe-layer spin structure does not change just by zero-field cooling the sample in remanence. For Fe/FeF{sub 2}, a continuous non-monotonic change of the remanent-state Fe spin structure was observed by cooling from 300 K to 18 K. NRS of synchrotron radiation was used to investigate the temperature- and depth-dependent Fe-layer spin structure during magnetization reversal in pseudo-twinned Fe/MnF{sub 2}. A depthdependent Fe spin structure in an applied magnetic field (applied along the bisector of the twin domains) was observed at 10 K, where the Fe spins closer to the interface are not aligned along the field direction. The depth-dependence disappears at 150 K. (orig.)

F.F.F.F. ehetega Soomes

Index Scriptorium Estoniae

2001-01-01

Põhjamaades toimuva Baltimaade kultuurifestivali raames rühmituse F.F.F.F. ehtenäitus "Igapäeva leib" Porvoos kuni 30. IX, Turus 5.-28. X. Eksponeeritakse kunstnike viimasel aastal valminud töid leivaküpsetamisele viitavates ahjuvormides.

miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb

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Zeyu Chen

2017-09-01

Full Text Available MicroRNAs play an important role in T cell responses. However, how microRNAs regulate CD8 T cell memory remains poorly defined. Here, we found that miR-150 negatively regulates CD8 T cell memory in vivo. Genetic deletion of miR-150 disrupted the balance between memory precursor and terminal effector CD8 T cells following acute viral infection. Moreover, miR-150-deficient memory CD8 T cells were more protective upon rechallenge. A key circuit whereby miR-150 repressed memory CD8 T cell development through the transcription factor c-Myb was identified. Without miR-150, c-Myb was upregulated and anti-apoptotic targets of c-Myb, such as Bcl-2 and Bcl-xL, were also increased, suggesting a miR-150-c-Myb survival circuit during memory CD8 T cell development. Indeed, overexpression of non-repressible c-Myb rescued the memory CD8 T cell defects caused by overexpression of miR-150. Overall, these results identify a key role for miR-150 in memory CD8 T cells through a c-Myb-controlled enhanced survival circuit.

Nuclear safety and radiation protection report of EdF's Tricastin operational hot base nuclear facilities (BCOT) - 2010

International Nuclear Information System (INIS)

2011-06-01

This safety report was established under the article 21 of the French law no. 2006-686 of June 13, 2006 relative to nuclear safety and information transparency. It presents, first, the Tricastin operational hot base facility (INB no. 157, Bollene, Vaucluse (FR)), a nuclear workshop for storage and maintenance and qualification operations on some EdF equipments. Then, the nuclear safety and radiation protection measures taken regarding the facility are reviewed: nuclear safety definition, radiation protection of intervening parties, safety and radiation protection improvement paths, crisis management, external and internal controls, technical situation of facilities, administrative procedures in progress. The incidents and accidents which occurred in 2010, if some, are reported as well as the effluents discharge in the environment. Finally, The radioactive materials and wastes generated by the facility is presented and sorted by type of waste, quantities and type of conditioning. The document concludes with a glossary and a list of recommendations from the Committees for health, safety and working conditions. (J.S.)

Nonlocal Operational Calculi for Dunkl Operators

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Ivan H. Dimovski

2009-03-01

Full Text Available The one-dimensional Dunkl operator $D_k$ with a non-negative parameter $k$, is considered under an arbitrary nonlocal boundary value condition. The right inverse operator of $D_k$, satisfying this condition is studied. An operational calculus of Mikusinski type is developed. In the frames of this operational calculi an extension of the Heaviside algorithm for solution of nonlocal Cauchy boundary value problems for Dunkl functional-differential equations $P(D_ku = f$ with a given polynomial $P$ is proposed. The solution of these equations in mean-periodic functions reduces to such problems. Necessary and sufficient condition for existence of unique solution in mean-periodic functions is found.

Inherited effects in F1 progeny of partially sterile male phthorimaea operculella (Lepidoptera: Gelechiidae)

International Nuclear Information System (INIS)

Makee, H.; Saour, G.

1998-01-01

Adult male phthorimaea operculella (Zeller), were exposed to sub sterilizing doses of gamma irradiation: 100, 150 and 200 Gy. Inherited effects in the F 1 , progeny of irradiated male parents were examined. Mean developmental time and the percentage mortality of the F 1 progeny, of each examined dose, were higher than that of the control group. Moreover, the sex ratio of the F 1 , progeny was skewed in favor of the males. Mean longevity, fecundity, and the percentage fertility of the F 1 progeny were lower than those of their parents and the control group. Mating ability and the frequency of mating of F 1 adults were similar to those of their partially sterile male parents and the control. The genetic basis of the F 1 characteristics has been discussed. The use of sub sterilizing doses of irradiation could be considered as an important component in a potato tuber moth control strategy. (author). 17 refs., 3 tabs

Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua

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Giuseppe Di Stefano

2016-01-01

Full Text Available Reseña de Emilio Pasquini, ed., Studi e problemi di critica testuale: 1960-2010. Per i 150 anni della Commissione per i testi di lingua, Commissione per i testi di lingua (Collezione di opere inedite o rare, 169, Bologna, 2012, x + 320 pp. ISBN: 9788898096152.

Receiver operating characteristic (ROC) curve for classification of {sup 18}F-NaF uptake on PET/CT

Energy Technology Data Exchange (ETDEWEB)

Valadares, Agnes Araujo, E-mail: agnesvaladares@me.com [Universidade de Sao Paulo (HC/FM/USP), SP (Brazil). Hospital das Clinicas. Fac. de Mediciana; Duarte, Paulo Schiavom; Ono, Carla Rachel; Coura-Filho, George Barberio; Sado, Heitor Naoki; Carvalho, Giovanna [Instituto do Cancer do Estado de Sao Paulo Octavio Frias de Oliveira (ICESP), Sao Paulo, SP (Brazil). Servico de Medicina Nuclear; Sapienza, Marcelo Tatit; Buchpiguel, Carlos Alberto [Universidade de Sao Paulo (FM/USP), Sao Paulo, SP (Brazil). Fac. de Medicina. Dept. de Radiologia e Oncologia

2016-01-15

Objective: To assess the cutoff values established by ROC curves to classify {sup 18}F-NaF uptake as normal or malignant. Materials and Methods: PET/CT images were acquired 1 hour after administration of 185 MBq of {sup 18}F-NaF. Volumes of interest (VOIs) were drawn on three regions of the skeleton as follows: proximal right humerus diaphysis (HD), proximal right femoral diaphysis (FD) and first vertebral body (VB1), in a total of 254 patients, totalling 762 VOIs. The uptake in the VOIs was classified as normal or malignant on the basis of the radiopharmaceutical distribution pattern and of the CT images. A total of 675 volumes were classified as normal and 52 were classified as malignant. Thirty-five VOIs classified as indeterminate or nonmalignant lesions were excluded from analysis. The standardized uptake value (SUV) measured on the VOIs were plotted on an ROC curve for each one of the three regions. The area under the ROC (AUC) as well as the best cutoff SUVs to classify the VOIs were calculated. The best cutoff values were established as the ones with higher result of the sum of sensitivity and specificity. Results: The AUCs were 0.933, 0.889 and 0.975 for UD, FD and VB1, respectively. The best SUV cutoffs were 9.0 (sensitivity: 73%; specificity: 99%), 8.4 (sensitivity: 79%; specificity: 94%) and 21.0 (sensitivity: 93%; specificity: 95%) for UD, FD and VB1, respectively. Conclusion: The best cutoff value varies according to bone region of analysis and it is not possible to establish one value for the whole body. (author)

Defect-induced wetting on BaF 2(111) and CaF 2(111) at ambient conditions

Science.gov (United States)

Cardellach, M.; Verdaguer, A.; Fraxedas, J.

2011-12-01

The interaction of water with freshly cleaved (111) surfaces of isostructural BaF2 and CaF2 single crystals at ambient conditions (room temperature and under controlled humidity) has been studied using scanning force microscopy in different operation modes and optical microscopy. Such surfaces exhibit contrasting behaviors for both materials: while on BaF2(111) two-dimensional water layers are formed after accumulation at step edges, CaF2(111) does not promote the formation of such layers. We attribute such opposed behavior to lattice match (mismatch) between hexagonal water ice and the hexagonal (111) surfaces of BaF2(CaF2). Optical microscope images reveal that this behavior also determines the way the surfaces become wetted at a macroscopic level.

Quantum statistical properties of orthonormalized eigenstates of the operator (a-circumflex f (n-circumflex))k

International Nuclear Information System (INIS)

Wang Jisuo; Jian Feng; Liu Tangkun

2002-01-01

The completeness of the k orthonormalized eigenstates of the operator (a-circumflex f (n-circumflex)) k (k≥3) is investigated. We introduce a new kind of higher-order squeezing and an antibunching. The properties of the Mth-order squeezing and the antibunching effect of the k states are studied. The result shows that these states may form a complete Hilbert space, and the Mth-order (M=(n+1/2)k; n=0,1,...) squeezing effects exist in all of the k states when k is even. There is an antibunching effect in all of the states. An alternative method for constructing the k states is proposed, and the result shows that all of them can be generated by linear superposition of the time-dependent nonlinear coherent states at different instants. (author)

Radiosynthesis of [F-18]fluoxetine as a potential radiotracer for serotonin reuptake sites

International Nuclear Information System (INIS)

Das, M.K.; Mukherjee, Jogeshwar

1993-01-01

Synthesis of 4-nitro-α-bromo-α,α-difluorotoluene was accomplished in two steps starting from 4-nitrobenzaldehyde, with a 30% overall yield. Radiolabeling of 4-nitro-α-bromo-α, α-difluorotoluene with no-carrier-added [ 18 F]fluoride provided 4-nitro-α,α-difluoro-α-[ 18 F] fluorotoluene in 2-4% yields with a specific activity of 2590 GBq/mmol (70 Ci/mmol). The effect of the reaction temperature on the radiochemical yield and specific activity of the radiolabeling reaction was studied. Radiochemical yields increased, whereas specific activity decreased, with increasing temperature. Radiosynthesis of [ 18 F] fluoxetine involved coupling of 4-nitro-α,α-difluoro-α-[ 18 F]fluorotoluene with the sodium alkoxide of (S)-3-(methylamino)-1-phenyl-1-propanol. The overall yield of HPLC purified [ 18 F]fluoxetine was 1-2% (decay-corrected; total radiosynthesis time, 150-180 min). The specific activity of the product was 1480 GBq/mmol (40 Ci/mmol). (Author)

Radiosynthesis of [F-18]fluoxetine as a potential radiotracer for serotonin reuptake sites

Energy Technology Data Exchange (ETDEWEB)

Das, M.K.; Mukherjee, Jogeshwar (Chicago Univ., IL (United States). Dept. of Radiology)

1993-05-01

Synthesis of 4-nitro-[alpha]-bromo-[alpha],[alpha]-difluorotoluene was accomplished in two steps starting from 4-nitrobenzaldehyde, with a 30% overall yield. Radiolabeling of 4-nitro-[alpha]-bromo-[alpha], [alpha]-difluorotoluene with no-carrier-added [[sup 18]F]fluoride provided 4-nitro-[alpha],[alpha]-difluoro-[alpha]-[[sup 18]F] fluorotoluene in 2-4% yields with a specific activity of 2590 GBq/mmol (70 Ci/mmol). The effect of the reaction temperature on the radiochemical yield and specific activity of the radiolabeling reaction was studied. Radiochemical yields increased, whereas specific activity decreased, with increasing temperature. Radiosynthesis of [[sup 18]F] fluoxetine involved coupling of 4-nitro-[alpha],[alpha]-difluoro-[alpha]-[[sup 18]F]fluorotoluene with the sodium alkoxide of (S)-3-(methylamino)-1-phenyl-1-propanol. The overall yield of HPLC purified [[sup 18]F]fluoxetine was 1-2% (decay-corrected; total radiosynthesis time, 150-180 min). The specific activity of the product was 1480 GBq/mmol (40 Ci/mmol). (Author).

Magnetic properties of lithium rare-earth fluorides: Ferromagnetism in LiErF4 and LiHoF4 and crystal-field parameters at the rare-earth and Li sites

DEFF Research Database (Denmark)

Hansen, P. E.; Johansson, Torben; Nevald, Rolf

1975-01-01

Single crystals of LiErF4 and LiHoF4 have been grown and their magnetic properties measured from 1.3 K to 300 K. LiHoF4 turned out to be a nearly ideal Ising ferromagnet with TC=1.30±0.05 K and a saturation magnetization along the crystalline c axis of (6.98±0.02)μB. In LiErF4 no ordering...... was observed, but extrapolation indicates that below 0.5 K it will be ferromagnetic with the magnetic moments in the crytalline ab plane. From the susceptibilities the crystal-field parameters Bnm with (n, m)=(2, 0), (4, 0), (4, 4), (6, 0), (6, 4) have been extracted giving for Er3+ in LiErF4: 430., -985......., 1185., -5., 740.+i135. (cm-1) and for Ho3+ in LiHoF4: 470., -825., 1050., -10., 760.+i150 (cm-1). The exchange constants were found to be small compared to the dipole interactions. Furthermore the 7Li NMR spectra have been obtained in these materials as well as in LiTbF4 thereby determining the second...

21 CFR 139.150 - Noodle products.

Science.gov (United States)

2010-04-01

... § 139.150 Noodle products. (a) Noodle products are the class of food each of which is prepared by drying... leaf, or any two or more of these, in a quantity which seasons the food. (2) Salt, in a quantity which... in with the common name of the ingredient; or in the case of bay leaves, the statement “Spiced...

microRNA-150 inhibits the formation of macrophage foam cells through targeting adiponectin receptor 2

Energy Technology Data Exchange (ETDEWEB)

Li, Jing [Department of Geratory, Linzi District People’s Hospital of Zibo City, Zibo, Shandong (China); Zhang, Suhua, E-mail: drsuhuangzhang@qq.com [Department of HealthCare, Qilu Hospital of Shandong University (Qingdao), Qingdao City, Qingdao (China)

2016-08-05

Transformation of macrophages into foam cells plays a critical role in the pathogenesis of atherosclerosis. The aim of this study was to determine the expression and biological roles of microRNA (miR)-150 in the formation of macrophage foam cells and to identify its functional target(s). Exposure to 50 μg/ml oxidized low-density lipoprotein (oxLDL) led to a significant upregulation of miR-150 in THP-1 macrophages. Overexpression of miR-150 inhibited oxLDL-induced lipid accumulation in THP-1 macrophages, while knockdown of miR-150 enhanced lipid accumulation. apoA-I- and HDL-mediated cholesterol efflux was increased by 66% and 43%, respectively, in miR-150-overexpressing macrophages relative to control cells. In contrast, downregulation of miR-150 significantly reduced cholesterol efflux from oxLDL-laden macrophages. Bioinformatic analysis and luciferase reporter assay revealed adiponectin receptor 2 (AdipoR2) as a direct target of miR-150. Small interfering RNA-mediated downregulation of AdipoR2 phenocopied the effects of miR-150 overexpression, reducing lipid accumulation and facilitating cholesterol efflux in oxLDL-treated THP-1 macrophages. Knockdown of AdipoR2 induced the expression of proliferator-activated receptor gamma (PPARγ), liver X receptor alpha (LXRα), ABCA1, and ABCG1. Moreover, pharmacological inhibition of PPARγ or LXRα impaired AdipoR2 silencing-induced upregulation of ABCA1 and ABCG1. Taken together, our results indicate that miR-150 can attenuate oxLDL-induced lipid accumulation in macrophages via promotion of cholesterol efflux. The suppressive effects of miR-150 on macrophage foam cell formation are mediated through targeting of AdipoR2. Delivery of miR-150 may represent a potential approach to prevent macrophage foam cell formation in atherosclerosis. -- Highlights: •miR-150 inhibits macrophage foam cell formation. •miR-150 accelerates cholesterol efflux from oxLDL-laden macrophages. •miR-150 suppresses macrophage foam cell

Role of 18F-F.D.G. PET/CT in management of patients with differentiated thyroid cancer

International Nuclear Information System (INIS)

Sibille, L.; Guillemard, S.; Eberle-Pouzeratte, M.C.; Espitalier-Riviere, C.; Faurous, P.; Artus, J.C.; Thezenas, S.; Lamy, P.J.; Rossi, M.

2010-01-01

18 F-F.D.G. PET/CT by combining both metabolic and anatomical information has proven to be an effective modality for detecting many types of cancer. Some differentiated forms of cancer like differentiated thyroid carcinoma (D.T.C.) are less F.D.G. avid and thus less easily detectable. Nevertheless 18 F-F.D.G. PET/CT has been proved useful in D.T.C. especially in case of suspected recurrent disease with negative whole-body radioiodine scintigraphy ( 131 I W.B.S.) and elevated thyroglobulin (Tg) or thyroglobulin autoantibodies (AbTg) levels. Impact on clinical management after 18 F-F.D.G. PET/CT examinations has been analyzed in patients with suspected recurrent D.T.C. in this retrospective study. Methodology. Fifty-five 18 F-F.D.G. PET/CT were performed in 45 patients with suspected recurrent or residual disease either because of elevated Tg/AbTg levels (n 45) or uncertain conventional imaging (n = 10) including 131 I W.B.S., cervical echography and CT scan if necessary. 18 F-F.D.G. PET/CT results were compared with histopathology and/or clinical follow-up with evaluation of impact on clinical management. Results. Twenty-nine exams were positive (53 %). There were 20 true-positive (T.P.) (14 locoregional relapses and six with distant metastases) and nine false-positive (F.P.) (all cervical). SUV max median values of hyper-metabolic foci were significantly higher in T.P. (5.1) than in F.P. (2.8). Overall, 20 (36 %) 18 F-F.D.G. PET/CT directly affected clinical management resulting in 13 (65 %) new surgical operations. Sensitivity, specificity, predictive positive value, predictive negative value and accuracy of 18 F-F.D.G. PET/CT were estimated for the whole group (respectively 83 %, 71 %, 69 %, 85 % and 76 %) and for two subgroups depending on Tg level (less or more than 1.2 ng/ml). Discussion and conclusion. 18 F-F.D.G. PET/CT is a powerful and useful tool in patients with suspected D.T.C. recurrence or residual disease and should be systematically performed when

F.F.F.F. / Pille Väljataga

Index Scriptorium Estoniae

Väljataga, Pille

2001-01-01

Rühmituse F.F.F.F. (Berit Teeäär, Maria Valdma, Ketli Tiitsar, Kaire Rannik, Kristi Paap) esinemisest 2000. a. suvel Leedus Niida kunstnike majas. Ehteid eksponeeriti kõrvuti nende 20-kordse suurendusega fotodega.

Parametric Analysis of the Exergoeconomic Operation Costs, Environmental and Human Toxicity Indexes of the MF501F3 Gas Turbine

Directory of Open Access Journals (Sweden)

Edgar Vicente Torres-González

2016-08-01

Full Text Available This work presents an energetic, exergoeconomic, environmental, and toxicity analysis of the simple gas turbine M501F3 based on a parametric analysis of energetic (thermal efficiency, fuel and air flow rates, and specific work output, exergoeconomic (exergetic efficiency and exergoeconomic operation costs, environmental (global warming, smog formation, acid rain indexes, and human toxicity indexes, by taking the compressor pressure ratio and the turbine inlet temperature as the operating parameters. The aim of this paper is to provide an integral, systematic, and powerful diagnostic tool to establish possible operation and maintenance actions to improve the gas turbine’s exergoeconomic, environmental, and human toxicity indexes. Despite the continuous changes in the price of natural gas, the compressor, combustion chamber, and turbine always contribute 18.96%, 53.02%, and 28%, respectively, to the gas turbine’s exergoeconomic operation costs. The application of this methodology can be extended to other simple gas turbines using the pressure drops and isentropic efficiencies, among others, as the degradation parameters, as well as to other energetic systems, without loss of generality.

Frame approximation of pseudo-inverse operators

DEFF Research Database (Denmark)

Christensen, Ole

2001-01-01

Let T denote an operator on a Hilbert space (H, [.,.]), and let {f(i)}(i=1)(infinity) be a frame for the orthogonal complement of the kernel NT. We construct a sequence of operators {Phi (n)} of the form Phi (n) (.) = Sigma (n)(i=1) [., g(t)(n)]f(i) which converges to the psuedo-inverse T+ of T i...... in the strong operator topology as n --> infinity. The operators {Phi (n)} can be found using finite-dimensional methods. We also prove an adaptive iterative version of the result. (C) 2001 Academic Press....

Expression of CD150 in tumors of the central nervous system: identification of a novel isoform.

Directory of Open Access Journals (Sweden)

Olga Romanets-Korbut

Full Text Available CD150 (IPO3/SLAM belongs to the SLAM family of receptors and serves as a major entry receptor for measles virus. CD150 is expressed on normal and malignant cells of the immune system. However, little is known about its expression outside the hematopoietic system, especially tumors of the central nervous system (CNS. Although CD150 was not found in different regions of normal brain tissues, our immunohistochemical study revealed its expression in 77.6% of human CNS tumors, including glioblastoma, anaplastic astrocytoma, diffuse astrocytoma, ependymoma, and others. CD150 was detected in the cytoplasm, but not on the cell surface of glioma cell lines, and it was colocalized with the endoplasmic reticulum and Golgi complex markers. In addition to the full length mRNA of the mCD150 splice isoform, in glioma cells we found a highly expressed novel CD150 transcript (nCD150, containing an 83 bp insert. The insert is derived from a previously unrecognized exon designated Cyt-new, which is located 510 bp downstream of the transmembrane region exon, and is a specific feature of primate SLAMF1. Both mCD150 and nCD150 cDNA variants did not contain any mutations and had the leader sequence. The nCD150 transcript was also detected in normal and malignant B lymphocytes, primary T cells, dendritic cells and macrophages; however, in glioma cells nCD150 was found to be the predominant CD150 isoform. Similarly to mCD150, cell surface expression of nCD150 allows wild type measles virus entry to the cell. Our data indicate that CD150 expression in CNS tumors can be considered a new diagnostic marker and potential target for novel therapeutic approaches.

40 CFR 417.150 - Applicability; description of the manufacture of spray dried detergents subcategory.

Science.gov (United States)

2010-07-01

... detergents, including but not limited to assembly and storage of raw materials, crutching, spray drying... manufacture of spray dried detergents subcategory. 417.150 Section 417.150 Protection of Environment... POINT SOURCE CATEGORY Manufacture of Spray Dried Detergents Subcategory § 417.150 Applicability...

Vida y muerte de un fármaco en el siglo XXI. Del libro Mediator® 150mg. Combien de morts? (I. Franchon, 2010 a la película La fille de Brest (E. Bercort, 2016

Directory of Open Access Journals (Sweden)

María Teresa ICART ISERN

2018-01-01

Full Text Available La fille de Brest, basada en hechos reales, relata los sucesos vividos por la Dra Irène Franchon y su equipo durantelos cautro años en los que se enfrentan al gigante farmacéutico francés Servier y a la Agencia de Seguridad Sanitariade Productos para la Salud. Su objetivo era conseguir la retirada del fármaco Mediator® 150mg, administrado comocoadyuvante en pacientes diabéticos y también como anorexígeno, causante de graves valvulopatías. Este artículosigue el curso del film La doctora de Brest (título de la versión española y presenta las diferentes actividades propiasde la investigación iniciada en el hospital de Brest (Bretaña, Francia en 2006, y que culminó con la retirada del fármacoen 2009. A Mediator® se le imputan al menos 500 muertes durante los treinta y tres años en los que estuvoen el mercado francés. El análisis de la película puede servir para la docencia ya que permite observar la labor dediferentes profesionales asistenciales (cardiólogos, neumólogos, enfermeras de investigación, estadísticos, etc. yde la administración sanitaria (farmacólogos. También ilustra problemas clínicos y éticos de interés para diferentesespecialidades (cardiología, endocrinología, etc..

Validade de indicadores de atividade física e comportamento sedentário da Pesquisa Nacional de Saúde do Escolar entre adolescentes do Rio de Janeiro, Brasil

Directory of Open Access Journals (Sweden)

Letícia Ferreira Tavares

2014-09-01

Full Text Available Analisou-se a validade relativa dos indicadores de atividade física do questionário utilizado na Pesquisa Nacional de Saúde do Escolar (PeNSE entre adolescentes da cidade do Rio de Janeiro, Brasil. Foram estudados 174 alunos. Avaliaram-se os seguintes indicadores referentes ao tempo semanal acumulado com a prática de atividade física: ATIVO-300MIN (acumulou 300 minutos ou mais; ATIVO-150MIN (acumulou 150 minutos ou mais; INATIVO (não praticou atividade física. Também foram estudados os indicadores de comportamento sedentário referentes ao tempo diário despendido assistindo TV, jogando videogame e usando computador. Foram comparados os resultados do questionário e dos três recordatórios de 24 horas. Os resultados de ATIVO-300MIN, ATIVO-150MIN e INATIVO gerados pela PeNSE apresentaram alta acurácia. Esses indicadores tiveram melhor desempenho que os de comportamento sedentário, tanto em relação às estimativas de frequência quanto em relação à sensibilidade, especificidade e índice de acurácia. Os indicadores de atividade física da PeNSE apresentaram validade relativa satisfatória.

Multi-kiloampere, electron-beam generation from bare aluminum photo-cathodes driven by an ArF laser

International Nuclear Information System (INIS)

Carlson, R.L.; Ridlon, R.N.; Seitz, G.J.; Hughes, T.P.

1997-01-01

An electron-beam-pumped laser operating at ArF (193 nm) producing up to 5.0 joules in a 150-ns pulse has been used to illuminate micro-machined aluminum cathodes. The cathode was pulsed from 2.25- up to 2.95-MV across a 20-cm-AK gap producing fields up to 145 kV/cm using REX (a 4-MeV, 5-kA, 100-ns pulsed diode). Extracted current versus laser power gives a quantum efficiency increasing with power density from 0.07 to 0.11%. The present work is significant in that the cathode operates in the presence of out-gassing materials with a background vacuum pressure in the mid 10 -6 torr region and 100-ns-long electron beams of up to 3 kA have been produced. Both emission limited (current follows laser pulse) and space-charge-limited (current follows pulsed power) regimes have been studied up to ∼ 50 A/cm 2 by varying the cathode diameter. The beam temperature has been measured to be < 5 eV and directly compared in the same experimental setup to velvet based cathodes that measure ∼ 100 eV

Department of the Navy Justification of Estimates for Fiscal Years 1988 and 1989 Submitted to Congress January 1987. Operation & Maintenance, Navy. Book 1. Budget Activity 1. Strategic Forces Budget Activity 2. General Purpose Forces Budget Activity 4. Airlift and Sealift.

Science.gov (United States)

1987-01-01

166 174 170 167 Config Change Rqsts 45 54 53 52 Config Audits 20 26 26 25 Manual Change Rqsts 516 500 489 477 Work Years 91 90 90 90 7) Noise Reduction... manual methods. 771 ’ 1 1-50 3442f/7 Activity Group: Space Systems Operations (cont’d) AMOUNT C. Other Program Growth in FY 1989 (878) 1) Space...P+WS htp ~ h Na vy lr,(j Ma? itf’ to a nri rt. r 1’r f 1, Pri y t, i lu, iwe, a t ion, t a t H % ;, i rndi t 04 l I r k 4, PMfi , . j(I l j ,’Ř

24 CFR 943.150 - What procurement standards apply to a PHA's joint venture partner?

Science.gov (United States)

2010-04-01

... a PHA's joint venture partner? 943.150 Section 943.150 Housing and Urban Development Regulations... HOUSING, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT PUBLIC HOUSING AGENCY CONSORTIA AND JOINT VENTURES Subsidiaries, Affiliates, Joint Ventures in Public Housing § 943.150 What procurement standards apply to a PHA...

Clinical role of 18F-fluorodeoxyglucose positron emission tomography/computed tomography in post-operative follow up of gastric cancer: Initial results

Institute of Scientific and Technical Information of China (English)

Long Sun; Xin-Hui Su; Yong-Song Guan; Wei-Ming Pan; Zuo-Ming Luo; Ji-Hong Wei; Hua Wu

2008-01-01

AIM: To evaluate the clinical role of 18F-fluorodeo-xyglucose positron emission and computed tomography(18F-FDG PET/CT) in detection of gastric cancer recur rence after initial surgical resection.METHODS: In the period from January 2007 to May 2008, 23 patients who had previous surgical resection of histopathologically diagnosed gastric cancer underwent a total of 25 18F-FDG PET/CT scans as follow-up visits in our center. The standard of reference for tumor recurrence consisted of histopathologic confirmation or clinical follow-up information for at least 5 mo after PET/CT examinations.RESULTS: PET/Cr was positive in 14 patients (61%)and negative in 9 (39%). When correlated with final diagnosis, which was confirmed by histopathologic evidence of tumor recurrence in 8 of the 23 patients(35%) and by clinical follow-up in 15 (65%), PET/CT was true positive in 12 patients, false positive in 2,true negative in 8 and false negative in 2. Overall,the accuracy of PET/CT was 82.6%, the negative predictive value (NPV) was 77.7%, and the positive predictive value (PPV) was 85.7%. The 2 false positive PET/CT findings were actually chronic inflammatory tissue lesions. For the two patients with false negative PET/CT, the final diagnosis was recurrence of mucinous adenocarcinoma in the anastomosis in one patient and abdominal wall metastasis in the other. Importantly,PET/CT revealed true-positive findings in 11 (47.8%)patients who had negative or no definite findings by CT. PET/CT revealed extra-abdominal metastases in 7 patients and additional esophageal carcinoma in onepatient. Clinical treatment decisions were changed in 7 (30.4%) patients after introducing PET/CT into theirconventional post-operative follow-up program.CONCLUSION: Whole body 18F-FDG PET/CT was highly effective in discriminating true recurrence in post-operative patients with gastric cancer and had important impacts on clinical decisions in a considerable portion of patients.

Development of Long-term Cooling Operation Strategy with H-SIT

International Nuclear Information System (INIS)

Jeon, In Seop; Kang, Hyun Gook

2016-01-01

In the current nuclear power plants (NPPs), most of the critical safety functions are provided by many active safety systems. Long-term cooling of core is an ultimate goal of all mitigation actions for plant safety and feed and bleed (F and B) operation strategy is one of long-term cooling strategies in conventional pressurized water reactor (PWR). The important point of F and B operation is that, in conventional mitigation strategy, injection for feed operation is performed by only high pressure injection (HPSI) pump. Low pressure injection (LPSI) pump such as shut down cooling pump (SCP) cannot be used for F and B operation. Thus, when F and B operation is needed, if high-pressure injection pump fails, core should be damaged. In this study, F and B operation strategy with LPSI and H-SIT is developed. This is a new concept for the long-term cooling operation. If this strategy is applied, low pressure injection pump can be successfully used for F and B operation thus operator has the additional mitigation way. As this strategy make plant safe even though HPSI and PAFS are both failed, it can effectively enhance the plant safety. For this strategy two RCGVSs and two POSRVs are needed as a depressurization system for bleed operation and only one LPSI is enough for feed operation. H-SIT operation is also needed to make up core inventory during bleed operation. For this operation, four H-SITs have to be used to make up core safely. Based on the risk analysis using PSA method, if this strategy is applied, core damage frequency is 1.868e-6 which declined 7 percent from original model.

Underground trials on a newly developed EDW 150-2 L unit

Energy Technology Data Exchange (ETDEWEB)

Wille, G.; Klimek, K.H.

1982-01-01

Coal-getting from medium thick coalbeds (> 1.7 m) requires high-performance shearer-loaders. Machine length and adjustability have to be such as to permit smooth cutting through geological faults. Furthermore they should be suitable to cut out niches for the AFC drives so that gateroads can be driven along with the face line. The newly developed EDW 150-2 L shearer-loader meets these expectations after various mechanical and electrical improvements. The unit proved its usefulness from the beginning and in the most difficult geological conditions where other shearer-loaders normally available for the range of coalbed thickness would mostly have failed. The multiple requirements and disturbances have led to a number of separate improvements and disturbances have led to a number of separate improvements which together contribute to a basic improvement of the machine concept as far as applications, operational flexibility and safety are concerned.

Production of LiF films for dosimetric thermoluminescence application; Producao de filmes de LiF para aplicacao em dosimetria termoluminescente

Energy Technology Data Exchange (ETDEWEB)

Mauricio, Claudia Lucia de Pinho

2000-12-01

This work studies the LiF monolayer and multilayer polycrystalline film's dosimetric properties. The films were produced by electron beam evaporation technique in aluminium and stainless steel substrates maintained at several temperatures. As dosimetric variable, the intensity of the thermoluminescent (TL) glow curve of the films was used. effects of the substrate type and temperature; of the addition of layers of Mg F{sub 2} NaF and Cu F{sub 2} to the LiF films; and of thermal treatments in the TL response of the produced films were studied. The microstructural characterization of the films was accomplished through measures of scanning electronic microscopy and grazing incidence X-rays diffraction analysis. The dosimetric characterization was made of gamma radiation exposure in a {sup 60} Co source, with kerma from 0,1 to 500 Gy. Studies of reproducibility, homogeneity, stability and other environmental effects were also made. LiF and Cu F{sub 2}: LiF; Mg F{sub 2} films were the only ones that presented mechanical stability and reproducibility of the TL emission. There is a strong indication of some correlation between the residual tension fields inside the films and the intensity of its TL emission peaks. LiF monolayer films present supralinear behaviour from 0,2 to 100 Gy. These films present a main TL glow peak around 150 deg C, whose half-time is about 30 days. Its volumetric sensitivity can reach about 60 times that of LiF powder and about 0,25 that of TLD100 (LiF:Mg, Ti commercial dosimeter from Harshaw Chemical Co.) The homogeneity and reproducibility inside a same film batch is better than 12% for 95% confidence level. Cu F{sub 2} : LiF: Mg F{sub 2} films present linear behaviour from 3 to 500 Gy and its main TL glow peak around 200 deg C did not present any fading for a a period of 30 days, in laboratory conditions. This glow peak is characteristic of the Mg doping of LiF, which confirms the diffusion of Mg ions from the Mg F{sub 2} layer to the LiF

Extending the performance of KrF laser for microlithography by using novel F2 control technology

Science.gov (United States)

Zambon, Paolo; Gong, Mengxiong; Carlesi, Jason; Padmabandu, Gunasiri G.; Binder, Mike; Swanson, Ken; Das, Palash P.

2000-07-01

Exposure tools for 248nm lithography have reached a level of maturity comparable to those based on i-line. With this increase in maturity, there is a concomitant requirement for greater flexibility from the laser by the process engineers. Usually, these requirements pertain to energy, spectral width and repetition rate. By utilizing a combination of laser parameters, the process engineers are often able to optimize throughput, reduce cost-of-operation or achieve greater process margin. Hitherto, such flexibility of laser operation was possible only via significant changes to various laser modules. During our investigation, we found that the key measure of the laser that impacts the aforementioned parameters is its F2 concentration. By monitoring and controlling its slope efficiency, the laser's F2 concentration may be precisely controlled. Thus a laser may tune to operate under specifications as diverse as 7mJ, (Delta) (lambda) FWHM < 0.3 pm and 10mJ, (Delta) (lambda) FWHM < 0.6pm and still meet the host of requirements necessary for lithography. We discus this new F2 control technique and highlight some laser performance parameters.

Performance evaluation of a fully depleted monolithic pixel detector chip in 150 nm CMOS technology

International Nuclear Information System (INIS)

Obermann, Theresa

2017-06-01

The depleted monolithic active pixel sensor (DMAPS) is a new concept integrating full CMOS circuitry onto a (fully) depletable silicon substrate wafer. The realization of prototypes of the DMAPS concept relies on the availability of multiple well CMOS processes and highly resistive substrates. The CMOS foundry ESPROS Photonics offers both and was chosen for prototyping. Two prototypes, EPCB01 and EPCB02, developed in a 150 nm process on a highly resistive n-type wafer of 50 μm thickness, were characterized. The prototypes have 352 square pixels of 40 μm pitch and a small n-well charge collection node with very low capacitance of 5 fF (n + -implantation size: 5 μm x 5 μm) and about 150 transistors per pixel (CSA and discriminator plus a small digital part). The characterization of the prototypes demonstrates the proof of principle of the concept. Prior to irradiation the prototypes show a signal from a minimum ionizing particle ranging from 2400 e - to 3000 e - while the noise is 30 e - due to the low capacitance. After the irradiation of the prototypes with neutrons up to a fluence of 5 x 10 14 neutrons/cm 2 the performance suffers from the radiation damage leading to a signal of 1000 e - and a higher noise of 60 e - due to the increase of the leakage current. The detection efficiency of the prototypes reduces from 94 % to 26 % after the fluence of 5 x 10 14 particles/cm 2 . Due to the small fill factor the detection efficiency shows are strong dependence on the position within the pixel after irradiation. Thus the DMAPS concept with low fill factor can be used for precise vertex reconstruction in High Energy Physics experiments without severe performance loss up to moderate fluences (< 1 x 10 14 particles/cm 2 ). The expected particle fluences inside of the volume of the upgrade of the ATLAS pixel detector exceed this limit. However, possible applications could be at future linear collider (ILC or CLIC) experiments and B-factories where the low material budget

miR-150-5p inhibits hepatoma cell migration and invasion by targeting MMP14.

Directory of Open Access Journals (Sweden)

Tao Li

Full Text Available Hepatocellular carcinoma (HCC is one of the leading causes of cancer-related mortality worldwide. Despite progress in diagnostics and treatment of HCC, its prognosis remains poor because the molecular mechanisms underlying hepatocarcinogenesis are not well understood. In the study, we focused on identifying the role of miRNAs in HCC progression. miRNA microarray was used to analyze the differentially expressed miRNAs, and the results were validated by qPCR. We found that the miR-150-5p expression is down-regulated in HCC tissues compared with pair non-tumor tissues. miR-150-5p expression is also decreased in metastatic cancer tissues compared with pair primary tissues, indicating that miR-150-5p may be involved in HCC metastasis. Functionally, miR-150-5p inhibition significantly promotes hepatoma cell migration and invasion, whereas miR-150-5p overexpression suppresses cancer cell migration and invasion in vitro. The matrix metalloproteinase 14 (MMP14 is identified as a new target gene of miR-150-5p. miR-150-5p markedly inhibits MMP14 expression in hepatoma cells, and miR-150-5p expression is negative correlation with MMP14 expression in vivo. More important, re-expression of MMP14 in hepatoma cells partially reverses the effect of miR-150-5p in inhibiting cell invasion.

Summary of breakout Session F2: F2, decision support systems: Knowledge systems

International Nuclear Information System (INIS)

Anon.

1992-01-01

The discussions in breakout session F2 are summarized. The topics discussed include contingency planning, environmental sensitivity, countermeasures planning tools, cleanup operations management, and logistics support systems. General comments, concerns and major research issues are summarized

The generalized heavy free gas thermalization operator

International Nuclear Information System (INIS)

Pitcher, H.H.W.

1963-05-01

This paper gives an introduction to the generalized heavy free gas (Horowitz) thermalization operator, which is a device for simplifying thermalization calculations. Analytical, experimental,and numerical methods for determining the energy-dependent function f in the operator are discussed. The dependence of f on the nature of the moderator, its temperature, and the absorption of the system are investigated, using a program FOCS which derives f's from DSN (multigroup) thermal spectra; it is found that for most purposes the dependence on absorption is negligible except when Pu240 is present. The sensitivity of calculated spectra and reaction rate to changes in f is considered. f is given for graphite at 300 and 600 deg. K. (author)

PET/CT studies of multiple myeloma using {sup 18}F-FDG and {sup 18}F-NaF: comparison of distribution patterns and tracers' pharmacokinetics

Energy Technology Data Exchange (ETDEWEB)

Sachpekidis, Christos [Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg (Germany); German Cancer Research Center, Medical PET Group - Biological Imaging Clinical Cooperation Unit Nuclear Medicine, Heidelberg (Germany); Goldschmidt, Hartmut; Hose, Dirk [University of Heidelberg, Medical Clinic V, Heidelberg (Germany); National Center for Tumor Diseases Heidelberg, Heidelberg (Germany); Pan, Leyun; Cheng, Caixia; Dimitrakopoulou-Strauss, Antonia [Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg (Germany); Kopka, Klaus [German Cancer Research Center, Division of Radiopharmaceutical Chemistry, Heidelberg (Germany); Haberkorn, Uwe [Clinical Cooperation Unit Nuclear Medicine, German Cancer Research Center, Heidelberg (Germany); University of Heidelberg, Division of Nuclear Medicine, Heidelberg (Germany)

2014-07-15

The aim of this prospective study is to evaluate the combined use of fluorine-18 fluorodeoxyglucose ({sup 18}F-FDG) and fluorine-18 sodium fluoride ({sup 18}F-NaF) PET/CT in the skeletal assessment of patients with multiple myeloma (MM) and to compare the efficacy of these two PET tracers regarding detection of myeloma-indicative osseous lesions. The study includes 60 patients with multiple myeloma (MM) diagnosed according to standard criteria. All patients underwent dynamic (dPET/CT) scanning of the pelvis as well as whole body PET/CT studies with both tracers. The interval between the two exams was one day. Sites of focal increased {sup 18}F-FDG uptake were considered as highly suspicious of myelomatous involvement. The lesions detected on the {sup 18}F-NaF PET/CT scans were then correlated with those detected on {sup 18}F-FDG PET/CT, which served as a reference. Moreover, the {sup 18}F-FDG PET/CT results were also correlated with the low-dose CT findings. The evaluation of dPET/CT studies was based on qualitative evaluation, SUV calculation, and quantitative analysis based on a 2-tissue compartment model and a non-compartmental approach. Whole body {sup 18}F-FDG PET/CT revealed approximately 343 focal lesions while {sup 18}F-NaF PET/CT revealed 135 MM-indicative lesions (39 % correlation). CT demonstrated 150 lesions that correlated with those in {sup 18}F-FDG PET/CT (44 % correlation). Six patients demonstrated a diffuse pattern of disease with {sup 18}F-FDG, while 15 of them had a mixed (diffuse and focal) pattern of skeletal {sup 18}F-FDG uptake. A high number of degenerative, traumatic and arthritic disease lesions were detected with {sup 18}F-NaF PET/CT. In three patients with multiple focal {sup 18}F-FDG-uptake, {sup 18}F-NaF PET/CT failed to demonstrate any bone lesion. The dPET/CT scanning of the pelvic area with {sup 18}F-FDG and {sup 18}F-NaF revealed 77 and 24 MM-indicative lesions, respectively. Kinetic analysis of {sup 18}F-FDG revealed the

Changes of Dielectric Properties induced by Fast neutrons in Tissue Equivalent Plastic A-150

International Nuclear Information System (INIS)

Abdou, M.S.

2000-01-01

Tissue equivalent plastic A-150 (TEP A-150) samples are exposed to fast neutrons. Dielectric studies for TEP A-150 are carried out in the frequency range from 40 Hz to 4 MHz in the temperature range 295-343 K. The obtained data revealed that, both the dielectric properties and conductivity sigma ac (omega) of TEP A-150 are altered when irradiated by a relatively high fast neutron dose (15 Sv). The values of dielectric constant and conductivity are increased for the irradiated samples to about 24% than the blank samples

MicroRNA-150 protects the mouse heart from ischaemic injury by regulating cell death

Science.gov (United States)

Tang, Yaoping; Wang, Yongchao; Park, Kyoung-mi; Hu, Qiuping; Teoh, Jian-peng; Broskova, Zuzana; Ranganathan, Punithavathi; Jayakumar, Calpurnia; Li, Jie; Su, Huabo; Tang, Yaoliang; Ramesh, Ganesan; Kim, Il-man

2015-01-01

Aims Cardiac injury is accompanied by dynamic changes in the expression of microRNAs (miRs). For example, miR-150 is down-regulated in patients with acute myocardial infarction, atrial fibrillation, dilated and ischaemic cardiomyopathy as well as in various mouse heart failure (HF) models. Circulating miR-150 has been recently proposed as a better biomarker of HF than traditional clinical markers such as brain natriuretic peptide. We recently showed using the β-arrestin-biased β-blocker, carvedilol that β-arrestin1-biased β1-adrenergic receptor cardioprotective signalling stimulates the processing of miR-150 in the heart. However, the potential role of miR-150 in ischaemic injury and HF is unknown. Methods and results Here, we show that genetic deletion of miR-150 in mice causes abnormalities in cardiac structural and functional remodelling after MI. The cardioprotective roles of miR-150 during ischaemic injury were in part attributed to direct repression of the pro-apoptotic genes egr2 (zinc-binding transcription factor induced by ischaemia) and p2x7r (pro-inflammatory ATP receptor) in cardiomyocytes. Conclusion These findings reveal a pivotal role for miR-150 as a regulator of cardiomyocyte survival during cardiac injury. PMID:25824147

IlOTI-OPERATION AL INSTRtJCTION .f\\.I... SYSTEMS MODEL

African Journals Online (AJOL)

Navy and. R. F. Mager's. Criteria. Referenced. Instruction. Model for Analysis. Design and ... Naval educational pol icy of the U.S Navy and of .... skills or abilities which are required as the entry .... development provides for a self correcting, self.

Synthesis and X-ray crystal structure of (OsO(3)F(2))(2)2XeOF(4) and the Raman spectra of (OsO(3)F(2))(infinity), (OsO(3)F(2))(2), and (OsO(3)F(2))(2)2XeOF(4).

Science.gov (United States)

Hughes, Michael J; Mercier, Hélène P A; Schrobilgen, Gary J

2009-05-18

The adduct, (OsO(3)F(2))(2)2XeOF(4), was synthesized by dissolution of the infinite chain polymer, (OsO(3)F(2))(infinity), in XeOF(4) solvent at room temperature followed by removal of excess XeOF(4) under dynamic vacuum at 0 degrees C. Continued pumping at 0 degrees C resulted in removal of associated XeOF(4), yielding (OsO(3)F(2))(2), a new low-temperature phase of OsO(3)F(2). Upon standing at 25 degrees C for 1(1)/(2) h, (OsO(3)F(2))(2) underwent a phase transition to the known monoclinic phase, (OsO(3)F(2))(infinity). The title compounds, (OsO(3)F(2))(infinity), (OsO(3)F(2))(2), and (OsO(3)F(2))(2)2XeOF(4) have been characterized by low-temperature (-150 degrees C) Raman spectroscopy. Crystallization of (OsO(3)F(2))(2)2XeOF(4) from XeOF(4) solution at 0 degrees C yielded crystals suitable for X-ray structure determination. The structural unit contains the (OsO(3)F(2))(2) dimer in which the OsO(3)F(3) units are joined by two Os---F---Os bridges having fluorine bridge atoms that are equidistant from the osmium centers (2.117(5) and 2.107(4) A). The dimer coordinates to two XeOF(4) molecules through Os-F...Xe bridges in which the Xe...F distances (2.757(5) A) are significantly less than the sum of the Xe and F van der Waals radii (3.63 A). The (OsO(3)F(2))(2) dimer has C(i) symmetry in which each pseudo-octahedral OsO(3)F(3) unit has a facial arrangement of oxygen ligands with XeOF(4) molecules that are only slightly distorted from their gas-phase C(4v) symmetry. Quantum-chemical calculations using SVWN and B3LYP methods were employed to calculate the gas-phase geometries, natural bond orbital analyses, and vibrational frequencies of (OsO(3)F(2))(2), (OsO(3)F(2))(2)2XeOF(4), XeOF(4), OsO(2)F(4), and (mu-FOsO(3)F(2))(2)OsO(3)F(-) to aid in the assignment of the experimental vibrational frequencies of (OsO(3)F(2))(2), (OsO(3)F(2))(2)2XeOF(4), and (OsO(3)F(2))(infinity). The vibrational modes of the low-temperature polymeric phase, (OsO(3)F(2))(infinity), have been

Electrospark Deposition for Depot- and Field-Level Component Repair and Replacement of Hard Chromium Plating

Science.gov (United States)

2006-09-07

ducted away and removed by scrubbers . Wastes generated from plating operations must be disposed of as hazardous waste and plating operations must...specimens were austentized at 1875o F, held for approximately 45 minutes, quenched in dissociated ammonia to approximately 150o F, and tempered for two...Lab analysis labor no change Estimated based on previous plating CBAs Scrubber maintenance captured elsewhere Captured in total scrubber costs

Actividad física y su relación con la incidencia de demencia y mortalidad en la cohorte NEDICES

OpenAIRE

Llamas Velasco, Sara

2017-01-01

La falta de actividad física es considerada uno de los principales factores de riesgo de las enfermedades no transmisibles, contribuyendo sustancialmente a la carga mundial de morbilidad, mortalidad y discapacidad. En este contexto la OMS ha realizado una serie de recomendaciones, siendo en el caso de los adultos mayores de 65 años recomendable dedicar al menos 150 minutos por semana a realizar actividades físicas moderadas aeróbicas, o bien algún tipo de actividad física vigorosa aeróbica du...

A “dose on demand” Biomarker Generator for automated production of [18F]F− and [18F]FDG

International Nuclear Information System (INIS)

Awasthi, V.; Watson, J.; Gali, H.; Matlock, G.; McFarland, A.; Bailey, J.; Anzellotti, A.

2014-01-01

The University of Oklahoma—College of Pharmacy has installed the first Biomarker Generator (BG75) comprising a self-shielded 7.5-MeV proton beam positive ion cyclotron and an aseptic automated chemistry production and quality control module for production of [ 18 F]F − and clinical [ 18 F]FDG. Performance, reliability, and safety of the system for the production of “dose on demand” were tested over several months. No-carrier-added [ 18 F]F − was obtained through the 18 O(p,n) 18 F nuclear reaction by irradiation (20–40 min) of a >95% enriched [ 18 O]H 2 O target (280 μl) with a 7.5-MeV proton beam (3.5–5.0 μA). Automated quality control tests were performed on each dose. The HPLC-based analytical methods were validated against USP methods of quality control. [ 18 F]FDG produced by BG75 was tested in a mouse tumor model implanted with H441 human lung adenocarcinoma cells. After initial installment and optimization, the [ 18 F]F − production has been consistent since March 2011 with a maximum production of 400 to 450 mCi in a day. The average yield is 0.61 mCi/min and 0.92 mCi/min at 3.8 µA and 5 µA, respectively. The current target window has held up for over 25 weeks against >400 bombardment cycles. [ 18 F]FDG production has been consistent since June 2012 with an average of six doses/day in an automated synthesis mode (RCY≈50%). The release criteria included USP-specified limits for pH, residual solvents (acetonitrile/ethanol), kryptofix, radiochemical purity/identity, and filter integrity test. The entire automated operation generated minimal radiation exposure hazard to the operator and environment. As expected, [ 18 F]FDG produced by BG75 was found to delineate tumor volume in a mouse model of xenograft tumor. In summary, production and quality control of “[ 18 F]FDG dose on demand” have been accomplished in an automated and safe manner by the first Biomarker Generator. The implementation of a cGMP quality system is under way towards

Quantification of [18F]FDOPA and [18F]-3-OMFD in pig serum - a new TLC method in comparison with HPLC

International Nuclear Information System (INIS)

Pawelke, B.; Fuechtner, F.; Bergmann, R.; Brust, P.

2002-01-01

A novel TLC method for convenient quantification of [ 18 F]FDOPA and [ 18 F]-3-OMFD in routine operation was developed and the results assessed in comparison with an HPLC analysis. The two methods were found to correlate well. [ 18 F]fluoride which resisted determination on HPLC RP-18 columns was also quantified by TLC. (orig.)

A Study on the Operation Strategy for Combined Accident including TLOFW accident

International Nuclear Information System (INIS)

Kim, Bo Gyung; Kang, Gook Young; Yoon, Ho Joon

2014-01-01

It is difficult for operators to recognize the necessity of a feed-and-bleed (F-B) operation when the loss of coolant accident and failure of secondary side occur. An F-B operation directly cools down the reactor coolant system (RCS) using the primary cooling system when residual heat removal by the secondary cooling system is not available. The plant is not always necessary the F-B operation when the secondary side is failed. It is not necessary to initiate an F-B operation in the case of a medium or large break because these cases correspond to low RCS pressure sequences when the secondary side is failed. If the break size is too small to sufficiently decrease the RCS pressure, the F-B operation is necessary. Therefore, in the case of a combined accident including a secondary cooling system failure, the provision of clear information will play a critical role in the operators' decision to initiate an F-B operation. This study focuses on the how we establish the operation strategy for combined accident including the failure of secondary side in consideration of plant and operating conditions. Previous studies have usually focused on accidents involving a TLOFW accident. The plant conditions to make the operators confused seriously are usually the combined accident because the ORP only focuses on a single accident and FRP is less familiar with operators. The relationship between CET and PCT under various plant conditions is important to decide the limitation of initiating the F-B operation to prevent core damage

Linear attenuation coefficients of tissues from 1 keV to 150 keV

Science.gov (United States)

Böke, Aysun

2014-09-01

The linear attenuation coefficients and three interaction processes have been computed for liver, kidney, muscle, fat and for a range of x-ray energies from 1 keV to 150 keV. Molecular photoelectric absorption cross sections were calculated from atomic cross section data. Total coherent (Rayleigh) and incoherent (Compton) scattering cross sections were obtained by numerical integration over combinations of F2m(x) with the Thomson formula and Sm(x) with the Klein-Nishina formula, respectively. For the coherent (Rayleigh) scattering cross section calculations, molecular form factors were obtained from recent experimental data in the literature for values of xelements involved in tissue composition is 5 for liver, 47 for kidney, 44 for muscle and 3 for fat. The results are compared with previously published experimental and theoretical linear attenuation coefficients. In general, good agreement is obtained. The molecular form factors and scattering functions and cross sections are incorporated into a Monte Carlo program. The energy distributions of x-ray photons scattered from tissues have been simulated and the results are presented.

Oxygen influence on luminescence properties of rare-earth doped NaLaF{sub 4}

Energy Technology Data Exchange (ETDEWEB)

Tuomela, A., E-mail: anu.tuomela@oulu.fi [Research Center of Molecular Materials, University of Oulu, P.O. Box 3000, FIN-90014 (Finland); Pankratov, V., E-mail: vladimirs.pankratovs@oulu.fi [Research Center of Molecular Materials, University of Oulu, P.O. Box 3000, FIN-90014 (Finland); Sarakovskis, A.; Doke, G.; Grinberga, L. [Institute of Solid State Physics, University of Latvia, 8 Kengaraga, LV-1063 Riga (Latvia); Vielhauer, S. [Institute of Physics, University of Tartu, Riia 142, Tartu 51014 (Estonia); Huttula, M. [Research Center of Molecular Materials, University of Oulu, P.O. Box 3000, FIN-90014 (Finland)

2016-11-15

Luminescence properties of erbium and europium doped NaLaF{sub 4} with different oxygen content have been studied. Vacuum ultraviolet (VUV) excitation luminescence spectroscopy technique has been applied by using synchrotron radiation excitation. It was found that oxygen impurity leads to significant degradation of Er{sup 3+} or Eu{sup 3+} emission under VUV excitation. The intensive O{sup 2−}–Er{sup 3+} charge transfer excitation band has been detected from oxygen abundant NaLaF{sub 4} in the 150–165 nm spectral range. This band reveals a competing absorption mechanism in oxygen containing NaLaF{sub 4}. It is clearly demonstrated that one reason for the Er{sup 3+} emission degradation in oxygen abundant NaLaF{sub 4} is strong suppression of 4f–5d transitions in Er{sup 3+} ion. The degradation of the Eu{sup 3+} emission under VUV excitation was explained by diminishing of F{sup −}–Eu{sup 3+} charge transfer absorption band as well as by competing relaxation centers in the oxygen abundant NaLaF{sub 4}.

Pionic decays of phi (1020) and f' (1514)

International Nuclear Information System (INIS)

Pasupathy, J.; Singh, C.A.

1978-01-01

The decay amplitudes phi (1020) → 3π and f' (1514) → ππ are calculated using unitarity corrections to the Okubo-Zweig-Iizuka rule. We use dispersion relations for the amplitudes phi → rhoπ and f' → ππ and evaluate the contributions arising from intermediate states such as KK-bar, K*K-bar, etc. The KK-bar intermediate state contributes to the absorptive part of the amplitude phi → rhoπ a value which corresponds to a partial width GAMMA (phi → 3π) of 150 keV. The contribution of the KK-bar and K*K-bar + K-barK* to the dispersive part of the amplitude phi → rhoπ within the context of approximations employed by us is somewhat larger and corresponds to a partial width of 900 keV for phi → 3π. For the f' → ππ amplitude we have evaluated the contributions of the KK-bar, etaeta, and K*K-bar + K-bar*K intermediate states using the dual model for the amplitudes KK-bar → ππ, etaeta → ππ, and K*K-bar → ππ. The effective strength of the amplitude f' → ππ arising from such unitarity corrections to the Okubo-Zweig-Iizuka rule corresponds to a partial width GAMMA (f' → ππ) of 170 keV via the absorptive part and a value of 500 keV via the dispersive part

The low-temperature structures of Hgsub(3-delta)SbF6 and Hgsub(3-delta)TaF6

International Nuclear Information System (INIS)

Tun, Z.; Brown, I.D.

1986-01-01

The Hg chains in both Hgsub(3-delta)SbF 6 and Hgsub(3-delta)TaF 6 order below room temperature. Down to about 190 K the ordering results from the interaction between parallel chains. It is short range and is different for the two compounds. Below 190 K both compounds transform to an isostructural long-range-ordered phase which is driven by the interaction between perpendicular chains. The structure of this phase in both compounds has been determined. Hgsub(3-delta)SbF 6 at 173 K, delta=0.134(1), Msub(r)=810.6(2). It is monoclinic but pseudotetragonal with I4 1 /amd, a=7.655(1), c=12.558(1) A, V=735.9(2) A 3 , Z=4, Dsub(x)=7.314(3) Mg m -3 , graphite-monochromated Mo Kα radiation, lambda=0.71069 A, μ=64.8 mm -1 , F(000)=1337.1(3). Hgsub(3-delta)TaF 6 at 150 K is isostructural but has delta=0.142(1), Msub(r)=868.2(2), a=7.634(1), c=12.610(2) A, V=734.9(2) A, Dsub(x)=7.844(3) Mg m -3 , μ=76.4 mm -1 , F(000)=1422.6(3). Comparison of the low-temperature structures with those at room temperature shows that the thermal contraction results from the shortening of interatomic distances associated with the weak bonds, with the result that the MF 6 (M=Sb, Ta) host lattice shrinks more than the Hg chains. Variation of the atomic displacement parameters with temperature indicates that the large librational displacements of the MF 6 ion result from thermal motion rather than static disorder. (orig.)

Identification of Key Residues in Virulent Canine Distemper Virus Hemagglutinin That Control CD150/SLAM-Binding Activity▿

Science.gov (United States)

Zipperle, Ljerka; Langedijk, Johannes P. M.; Örvell, Claes; Vandevelde, Marc; Zurbriggen, Andreas; Plattet, Philippe

2010-01-01

Morbillivirus cell entry is controlled by hemagglutinin (H), an envelope-anchored viral glycoprotein determining interaction with multiple host cell surface receptors. Subsequent to virus-receptor attachment, H is thought to transduce a signal triggering the viral fusion glycoprotein, which in turn drives virus-cell fusion activity. Cell entry through the universal morbillivirus receptor CD150/SLAM was reported to depend on two nearby microdomains located within the hemagglutinin. Here, we provide evidence that three key residues in the virulent canine distemper virus A75/17 H protein (Y525, D526, and R529), clustering at the rim of a large recessed groove created by β-propeller blades 4 and 5, control SLAM-binding activity without drastically modulating protein surface expression or SLAM-independent F triggering. PMID:20631152

33 CFR 165.150 - New Haven Harbor, Quinnipiac River, Mill River.

Science.gov (United States)

2010-07-01

... River, Mill River. 165.150 Section 165.150 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF... New Haven Harbor, Quinnipiac River, Mill River. (a) The following is a regulated navigation area: The... 303°T to point D at the west bank of the mouth of the Mill River 41°18′05″ N, 72°54′23″ W thence south...

Sandvik's HM 150 roller in action on the world's largest conveyor bridge in the Lusatia region; Sandvik HM 150 auf der weltgroessten Foerderbruecke in der Lausitz im Einsatz

Energy Technology Data Exchange (ETDEWEB)

Waliczek, Sven; Raddatz, Ulrich [Sandvik Mining and Construction Central Europe GmbH, Essen (Germany)

2010-09-15

Prince Herrmann Ludwig Heinrich von Pueckler-Muskau, a landscape gardening genius, built the Muskau Park in the Lusatia region in 1817 - it is part of a UNESCO world heritage site today. In the same era, 1850, the first lignite was mined in the region and still today, Vattenfall, the Swedish company, extracts lignite without subsidies - in Jaenschwalde among other places, one out of the five opencast mines currently in operation. As one of the largest employers and apprenticing companies in East Germany, Vattenfall currently employs almost 8000 employees and about 800 apprentices. Sandvik Mining and Construction also plays a leading role - in the literal sense. At the Jaenschwalde location there are 320 sets of 5-roller garlands of HM150 formed rollers in action on the overburden conveyor bridge AFB 60m (Figure 1) - on belt five, the main belt conveyor (belt type 3000 ST3000-18:8, idler spacing approx. 800 mm) and on belt eight, the stockpile belt conveyor (belt type 2750 ST2500-18:8, idler spacing approx. 800 mm). It all began in the spring of 2004. Bernhard Hofmayer, Production Manager at Sandvik, introduced the HM150 formed roller to Vattenfall. The engineers were impressed by the completely new design and the innovative assembly technique. The discussion about the advantages and disadvantages of the component optimised formed roller were ready to begin. (orig.)

Development of in-core measurements in the reactor KS-150

International Nuclear Information System (INIS)

Rana, S.B.

1977-01-01

Mapping of the neutron flux density distribution and of the neutron fluence distribution in the KS-150 reactor core was carried out using an in-core measuring system. The system allows the in-service monitoring of important operating properties of the reactor core and fuel elements and consists of a mapping fuel element assembly with built-in SPN detectors, of transmission paths and a computer facility. The measurement of the neutron flux, neutron fluence and temperature fields in the reactor core was carried out during the power start-up of the reactor using self-powered DPZ-1 detectors. The obtained data are given and the axial distribution of neutron flux is graphically represented for different values of burnup at the same configuration of regulating rods, as is the axial distribution of neutron fluence for different configurations of the regulating rods during operation, and the in-service neutron fluence distribution. The maximal fuel temperature of 500.2 degC was found at a distance of 291.2 cm from the upper boundary of the reactor core, at a neutron flux of 1.46x10 14 n/cm 2 s. In comparison with other methods, this method proved easy and quick, the results reliable, reactivity perturbance negligible and the fuel element cost increase a negligible 4%. Neutron flux mapping using in-core self-powered detectors will be performed on a wider scale. (J.P./J.O.)

Laser plasma instability experiments with KrF lasers

International Nuclear Information System (INIS)

Weaver, J. L.; Karasik, M.; Serlin, V.; Obenschain, S.; Chan, L-Y.; Kehne, D.; Schmitt, A. J.; Colombant, D.; Velikovich, A.; Oh, J.; Lehmberg, R. H.; Afeyan, B.; Phillips, L.; Seely, J.; Brown, C.; Feldman, U.; Aglitskiy, Y.; Mostovych, A. N.; Holland, G.

2007-01-01

Deleterious effects of laser-plasma instability (LPI) may limit the maximum laser irradiation that can be used for inertial confinement fusion. The short wavelength (248 nm), large bandwidth, and very uniform illumination available with krypton-fluoride (KrF) lasers should increase the maximum usable intensity by suppressing LPI. The concomitant increase in ablation pressure would allow implosion of low-aspect-ratio pellets to ignition with substantial gain (>20) at much reduced laser energy. The proposed KrF-laser-based Fusion Test Facility (FTF) would exploit this strategy to achieve significant fusion power (150 MW) with a rep-rate system that has a per pulse laser energy well below 1 MJ. Measurements of LPI using the Nike KrF laser are presented at and above intensities needed for the FTF (I∼2x10 15 W/cm 2 ). The results to date indicate that LPI is indeed suppressed. With overlapped beam intensity above the planar, single beam intensity threshold for the two-plasmon decay instability, no evidence of instability was observed via measurements of (3/2)ω o and (1/2)ω o harmonic emissions

Uji Performansi Getaran Mekanis dan Kebisingan Mist Blower Yanmar MK 150-B

Directory of Open Access Journals (Sweden)

Ahmad Noval Irvani

2012-10-01

Full Text Available Mist blower is one of the mechanization tool of agriculture considered as a tool that can assist humans in fertilizer and pesticides spreading activities. Levels of motor speed in the used mist blower were 1915, 4009, and 7227 rpm. Vibration measurements were conducted on the engine and handlebar control mist blower with the three-dimensional axes namely X, Y, and Z. Mist blower noise measurements were performed on the engine, operator's right ear and left ear. Based on the analysis of vibration and noise from the mist blower of type MK 150-B was obtained the safe limit values from the use of these tools. The safe limit of the use of mist blower in motor rotation speed of 1915, 4009, and 7227 rpm after being compared with the vibration and noise were 1 hour, 1 hour and 24 minutes respectively. The farther the distance from noise source, the lower the noise level too. Moreover objectivity study of operator was conducted. The first farmer was tired faster than the second farmer. In terms of age of farmer, the second farmer (60 years older than the first farmers (40 years, but this should not affect significantly. Activity on the previous day greatly affects the level of fatigue when operating the mist blower. This was because the first farmers did more activities and had rest periods that less than second farmer.

Mixer pump long term operations plan for Tank 241-SY-101 mitigation

International Nuclear Information System (INIS)

Irwin, J.J.

1994-01-01

This document provides the general Operations Plan for performance of the mixer pump long term operations for Tank 241-SY-101 mitigation of gas retention and periodic release in Tank 101-SY. This operations plan will utilize a 112 kW (150 hp) mixing pump to agitate/suspend the particulates in the tank

Avaliação funcional e histológica da tireoide de ovinos suplementados com fluoreto de sódio por um período de 150 dias Functional and histological evaluations of thyroid of sheep submitted to sodium fluoride administration

Directory of Open Access Journals (Sweden)

D.S. Prestes

2009-04-01

Full Text Available Avaliou-se o efeito da administração de fluoreto de sódio sobre a tireoide de 12 ovinos, distribuídos em dois grupos: o grupo controle (n=6 recebeu somente sal iodado (5g de NaCl/animal + 0,2ppm I/kg MS e o grupo tratado (n=6, sal iodado (5g de NaCl/animal + 0,2ppm I/kg MS adicionado de fluoreto de sódio (4,7mg F/kg de peso corporal, durante 150 dias. Amostras de sangue foram coletadas para análise sérica de I e F, triiodotironina (T3 e tetraiodotironina (T4 nos dias zero, 60, 90 e 150 de tratamento. Também se coletou urina, correspondente às 24 horas, para análise da excreção urinária de I e F. Após a eutanásia dos animais, a tireoide foi removida para posterior exame. Quanto ao I urinário, não foi observada diferença estatística entre os grupos controle e tratado e dentro de cada grupo, entre os tempos. As concentrações de T3 e T4 não diferiram entre os grupos e dentro de cada grupo nos diferentes tempos. Quanto à avaliação histopatológica da tireoide, não foram observadas alterações na integridade estrutural. Conclui-se que a administração crônica de fluoreto de sódio não interfere na função e na integridade histológica da glândula tireoide de ovinos com dieta não restritiva de iodo.The effect of sodium fluoride administration on thyroid function and morphology in sheep was evaluated using 12 lambs. Animals were allotted in two groups: control that received 5g NaCl + 0.2ppm I/kg DM and treated which received the same treatment plus sodium fluoride (4.7mg F/kg BW, daily, for 150 days. Blood samples were collected for determination of F, I, T3, and T4. Urine production was collected for measurement of F and I. After euthanasia at 150 days of treatment, thyroid glands were removed for analysis. No differences were found between or within groups for urinary I. Also, no differences were found for T3 and T4 on serum I between groups or among time points. No histological alterations were found in the thyroids

Clinical study of 18F-FDG PET/CT whole-body imaging in disseminated carcinoma of unknown primary site

International Nuclear Information System (INIS)

Wang Guohui; Liang Peiyan; Cai Yanjun; Zhang Weiguang; Xie Chuanmiao; Wu Peihong

2008-01-01

Objective: Carcinoma of unknown primary (CUP) is not uncommon in usual clinical settings. They are, by definition, those cases with clinically suspected primary malignancy but not revealed by conventional investigation. The aim of this study was to investigate the efficacy of whole-body 18 F-fluoro- deoxyglucose (FDG) PET/CT in detecting a primary neoplasm for these patients. Methods: A totle of 150 patients with retrievable records from 169 CUP patients were selected within a group of consecutive 2589 patients from Jan. 2006 to Jun. 2007. All cases underwent whole-body FDG PET/CT scan. The final diagnoses were confirmed by pathologic results, other imaging modalities or clinical follow-up. Results: Among 150 patients, primary tumor sites were successfully detected by whole-body 18 F-FDG PET/CT scan in 70 cases (46.7%), of which 52 were pathologically confirmed and 18 by clinical follow-up. And 38 cases (54.3%) were lung cancer, 8 (11.4%) were nasopharyngeal carcinoma, 13 (18.6%) in digestive sys- tem, and 11 (15.7%) in other systems. Three clinically suspected CUP cases with negative 18 F-FDG PET/ CT were subsequently confirmed of benign processes by clinical follow-up. Six patients were wrongly diagnosed by 18 F-FDG PET/CT, and 15 patients did not have a confirmed diagnosis by the end of research. The primary cause of malignancy after 18 F-FDG PET/CT remained obscure in 56 patients, only 3 of whom be- came known during the course of clinical follow-up (nasopharyngeal bladder and esophageal carcinoma). Conclusion: 18 F-FDG PET/CT whole-body imaging plays an important role in patients with metastatic CUP. (authors)

Radiation dose to construction workers at operating nuclear power plant sites. Volume 2. Appendices A--F. Final report, September 1975--September 1978

International Nuclear Information System (INIS)

Endres, G.W.R.; Shipler, D.B.

1978-12-01

These appendices contain the dosimetry procedures and details of the personnel and environmental dosimeters used for the Radiation Dose to Construction Workers at Operating Nuclear Power Plant Sites Study. A printout of the computer codes used to analyze dosimeter data is included along with all the raw data obtained. Appendices C through F contain computer output and log-normal plots of dosimetry data for environmental location and construction worker groups

Automated synthesis of n.c.a. [18F]FDOPA via nucleophilic aromatic substitution with [18F]fluoride

International Nuclear Information System (INIS)

Shen, B.; Ehrlichmann, W.; Uebele, M.; Machulla, H.-J.; Reischl, G.

2009-01-01

An improved, automated synthesis of [ 18 F]FDOPA including four synthetic steps (fluorination, reductive iodination, alkylation and hydrolysis) is reported with each step optimized individually. In a home-made automatic synthesizer, 9064±3076 MBq of [ 18 F]FDOPA were produced within 120 min from EOB (n=5). Radiochemical purity and enantiomeric excess were both ≥95%. Specific activity was ca. 50 GBq/μmol at EOS. This automatically operable synthesis is well suited for the multi-patient-dose routine production of n.c.a. [ 18 F]FDOPA.

7 CFR 1260.150 - Duties of the Board.

Science.gov (United States)

2010-01-01

... Agriculture Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE (MARKETING AGREEMENTS AND ORDERS; MISCELLANEOUS COMMODITIES), DEPARTMENT OF AGRICULTURE BEEF PROMOTION AND RESEARCH Beef Promotion and Research Order Cattlemen's Beef Promotion and Research Board § 1260.150 Duties of the Board...

GENETIC FACTORS INFLUENCING HEMOGLOBIN F LEVEL IN β-THALASSEMIA/HB E DISEASE.

Science.gov (United States)

Ruangrai, Waraporn; Jindadamrongwech, Sumalee

2016-01-01

Genetic factors influencing Hb F content in adult red blood cells include β-thalassemia genotypes, co-inheritance of α-thalassemia traits and single nucleotide polymorphisms (SNPs). Genotyping of α- and β-thalassemia and five SNPs in β-globin gene cluster previously identified in genome-wide association studies as being markers of elevated Hb F in β-thalassemia were performed in 81 subjects diagnosed with β-thalassemia/Hb E. Hb F levels are higher (0.9-7.1 g/dl) in subjects (n = 57) with the severe compared to mild β-thalassemia (0.8-2.5 g/ dl) (n = 4) genotypes, and are similarly low (0.7-3.5 g/dl) in those (n = 15) with α-thalassemia co-inheritance. Hb F levels in non-thalassemia controls (n = 150) range from 0 to 0.15 g/dl. The presence of homozygous minor alleles of the 5 SNPs are significant indicators of β-thalassemia/Hb E individuals with high Hb F (> 4 g/dl), independent of their thalassemia genotypes. Given that re-activation of γ-globin genes leads to amelioration of β-thalassemia severity, understanding how genetic factors up-regulate Hb F production may lead to possible therapeutic interventions, genetically or pharmacologically, of this debilitating disease in the not too distant future.

[150 years of medical mycology].

Science.gov (United States)

Gemeinhardt, H

1990-04-01

A short survey concerning the development of the medical mycology is presented covering the last 150 years (1839-1989). According to the interpretation of most of the distinguished authors, the year of Schönlein's publication, i.e. 1839, is to be considered as the origin of the medical mycology. Therefore, mycoses were the first infectious diseases the etiology of which were scientifically explained. Monographs and articles in manuals written in the most important world languages represent milestones in the historical development. Over large periods connected to and promoted by dermatology, increasingly this special field has developed to an important and autonomous part of medical microbiology.

A Study on the Deriving Requirements of ARGO Operation System

Directory of Open Access Journals (Sweden)

Yoon-Kyung Seo

2009-12-01

Full Text Available Korea Astronomy and Space Science Institute (KASI has been developing one mobile and one stationary SLR system since 2008 named as ARGO-M and ARGO-F, respectively. KASI finished the step of deriving the system requirements of ARGO. The requirements include definitions and scopes of various software and hardware components which are necessary for developing the ARGO-M operation system. And the requirements define function, performance, and interface requirements. The operation system consisting of ARGO-M site, ARGO-F site, and Remote Operation Center (ROC inside KASI is designed for remote access and the automatic tracking and control system which are the main operation concept of ARGO system. To accomplish remote operation, we are considering remote access to ARGO-F and ARGO-M from ROC. The mobile-phone service allows us to access the ARGO-F remotely and to control the system in an emergency. To implement fully automatic tracking and control function in ARGO-F, we have investigated and described the requirements about the automatic aircraft detection system and the various meteorological sensors. This paper addresses the requirements of ARGO Operation System.

Dispersion of UO2F2 aerosol and HF vapor in the operating floor during winter ventilation at the Paducah Gaseous Diffusion Plant

International Nuclear Information System (INIS)

Kim, S.H.; Chen, N.C.J.; Taleyarkhan, R.P.; Keith, K.D.; Schmidt, R.W.; Carter, J.C.

1996-01-01

The gaseous diffusion process is currently employed at two plants in the US: the Paducah Gaseous Diffusion Plant and the Portsmouth Gaseous Diffusion Plant. As part of a facility-wide safety evaluation, a postulated design basis accident involving large line-rupture induced releases of uranium hexafluoride (UF 6 ) into the process building of a gaseous diffusion plant (GDP) is evaluated. When UF 6 is released into the atmosphere, it undergoes an exothermic chemical reaction with moisture (H 2 O) in the air to form vaporized hydrogen fluoride (HF) and aerosolized uranyl fluoride (UO 2 F 2 ). These reactants disperse in the process building and transport through the building ventilation system. The ventilation system draws outside air into the process building, distributes it evenly throughout the building, and discharges it to the atmosphere at an elevated temperature. Since air is recirculated from the cell floor area to the operating floor, issues concerning in-building worker safety and evacuation need to be addressed. Therefore, the objective of this study is to evaluate the transport of HF vapor and UO 2 F 2 aerosols throughout the operating floor area following B-line break accident in the cell floor area

Pre-operative irradiation with rectal carcinoma - clinical practices and results

International Nuclear Information System (INIS)

Rendl, H.

1986-01-01

The goal of this work is to portray the effect of a high-dosed short-timed pre-irradiation on intra- and post-operative therapy of rectal carcinoma and the appearance of recidivistic tumors, respectively distant metastasis. This intermediate balance should help make the decision easier as to whether to continue to use this combined treatment form. The subjects consisted of 65 rectal carcinoma patients - pre-irradiated and operated - and 95 only operated patients. The irradiation was completed using a 8 MeV linear accelerator with ultra hard x-radiation. Dosing - (more than 80%) as short-timed irradiation with 16 Gy (4 x 4 Gy in 2 days) - 25 Gy (10 x 2,5 Gy in 12 days); average field size 150 mm x 150 mm. There were no significant differences with regard to intra- and post-operative complications, late complications or distant metastasis, but there was with tumor recidivision reduced with pre-irradiated. Regarding the survival rate, there was a slight tendency in favor of the pre-irradiated. (orig./MG) [de

The Art and Science of Operational Maneuver,

Science.gov (United States)

1988-05-04

Classification) The Art and Science of Operational Maneuver (U) 12. PERSONAL AUTHOR(S) MAJ Joseph Schroedel 13a. TYPE OF REPORT 13b. TIME COVERED 14...CLASSIFICATION OF THIS PAGE VA) CL LA S F1 EP {fJE ART ANQ SCIENCE OlF OPERAIl NAL MANUVER By6 Mal or Josepi~ Schroeci, L U. S. Arm~y H Aciv -darILC Ced M ili t...Studies ,nIgz’raph ApprovwA. Name of Student: Major Jonevh Schroedel. U.S. Army Title ot Monograph: The Art and Science of Operational Maneuver Approved By

Operant Conditioning for Special Educators.

Science.gov (United States)

Pedrini, Bonnie C.; Pedrini, D. T.

The paper briefly explains operant conditioning as it pertains to special educators. Operant conditioning is thought to be an efficient method for modifying student behavior. Using the B. F. Skinner frame of reference, operant conditioning is said to include behavior modification and therapy, programed instruction, and computer assisted and…

An assessment of the thermodynamic behaviour of neptunium in water and model groundwaters from 25 to 150 degrees C

International Nuclear Information System (INIS)

Lemire, R.J.

1984-03-01

Standard molal Gibbs energy of formation and entropy data for simple neptunium solids and aqueous neptunium complexes with OH - , Cl - , F - , CO 3 2- , PO 4 3- , SO-4 2- and Na + have been critically reviewed. Selected values are used with estimated heat capacity values to derive self-consistent analytical expressions for the temperature dependence of the standard molal Gibbs energies of formation of the species from 25 to 150 degrees C. The Gibbs energies have been used to evaluate the effect of different concentrations of ligands on the solubility of neptunium solids as a function of temperature. Potential-pH diagrams are given for neptunium in pure water and in two model groundwaters. Important deficiencies in the available thermodynamic data for neptunium species are discussed

Preparing Specialized Undergraduate Pilot Training Graduates for F-35A Training

Science.gov (United States)

2010-06-11

the two sides of this argument and analyze the new data acquired from an F-22A lead-in program and the fact that the F-35A has started flying with...flight operations under Instrument or Visual Flight Rules to include day / night IFR operations in the terminal and enroute environment. Have limited

Production of LiF films for dosimetric thermoluminescence application

International Nuclear Information System (INIS)

Mauricio, Claudia Lucia de Pinho

2000-12-01

This work studies the LiF monolayer and multilayer polycrystalline film's dosimetric properties. The films were produced by electron beam evaporation technique in aluminium and stainless steel substrates maintained at several temperatures. As dosimetric variable, the intensity of the thermoluminescent (TL) glow curve of the films was used. effects of the substrate type and temperature; of the addition of layers of Mg F 2 NaF and Cu F 2 to the LiF films; and of thermal treatments in the TL response of the produced films were studied. The microstructural characterization of the films was accomplished through measures of scanning electronic microscopy and grazing incidence X-rays diffraction analysis. The dosimetric characterization was made of gamma radiation exposure in a 60 Co source, with kerma from 0,1 to 500 Gy. Studies of reproducibility, homogeneity, stability and other environmental effects were also made. LiF and Cu F 2 : LiF; Mg F 2 films were the only ones that presented mechanical stability and reproducibility of the TL emission. There is a strong indication of some correlation between the residual tension fields inside the films and the intensity of its TL emission peaks. LiF monolayer films present supralinear behaviour from 0,2 to 100 Gy. These films present a main TL glow peak around 150 deg C, whose half-time is about 30 days. Its volumetric sensitivity can reach about 60 times that of LiF powder and about 0,25 that of TLD100 (LiF:Mg, Ti commercial dosimeter from Harshaw Chemical Co.) The homogeneity and reproducibility inside a same film batch is better than 12% for 95% confidence level. Cu F 2 : LiF: Mg F 2 films present linear behaviour from 3 to 500 Gy and its main TL glow peak around 200 deg C did not present any fading for a a period of 30 days, in laboratory conditions. This glow peak is characteristic of the Mg doping of LiF, which confirms the diffusion of Mg ions from the Mg F 2 layer to the LiF layer. The TL volumetric sensitivity of these

45 CFR 150.203 - Circumstances requiring CMS enforcement.

Science.gov (United States)

2010-10-01

... 45 Public Welfare 1 2010-10-01 2010-10-01 false Circumstances requiring CMS enforcement. 150.203... CARE ACCESS CMS ENFORCEMENT IN GROUP AND INDIVIDUAL INSURANCE MARKETS CMS Enforcement Processes for... requiring CMS enforcement. CMS enforces HIPAA requirements to the extent warranted (as determined by CMS) in...

F.F.F.F. armastab mõtestada ennast / Reet Varblane

Index Scriptorium Estoniae

Varblane, Reet, 1952-

2002-01-01

Rühmituse F.F.F.F. (Kristi Paap, Kaire Rannik, Berit Teeäär, Ketli Tiitsar, Maria Valdma) näitus "Meie igapäevane leib" 9. novembrini Hansapanga galeriis ja näitus "Pentagramm" 26. X-1. XII Tarbekunstimuuseumis

Pilot-scale ultrafiltration testing for the F and H area effluent treatment facility

International Nuclear Information System (INIS)

Kessler, J.L.

1984-01-01

An F and H Area Effluent Treatment Facility (F/H ETF) is being designed to treat low activity aqueous effluents which are produced from F and H Area daily operations. The treatment scheme for the F/H ETF will include pretreatment (pH adjustment and filtration) followed by Reverse Osmosis and/or Ion Exchange to remove dissolved species. Several alternative treatment processes are being considered for the F/H ETF. One of the alternatives in the pretreatment step is tubular Ultrafiltration (UF), using a dynamically formed zirconium oxide membrane supported on a porous stainless steel backing. Pilot-scale testing with a single membrane module (13 ft 2 area) and 200-Area effluent simulant has demonstrated that UF is a viable filtration option for the F/H ETF. UF testing at TNX has defined the operating conditions necessary for extended operation and also demonstrated excellent filtration performance (filtrate SDI 2 /day) flux and will provide excellent pretreatment for both reverse osmosis and ion exchange. 2 refs

Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study

International Nuclear Information System (INIS)

Chen, Yu-An; Huang, Wen-Sheng; Lin, Yaoh-Shiang; Cheng, Cheng-Yi; Liu, Ren-Shyan; Wang, Shyh-Jen; Li, I-Hsun; Huang, San-Yuan; Shiue, Chyng-Yann; Chen, Cheng-Yu; Ma, Kuo-Hsing

2012-01-01

Introduction: Serotonin transporter (SERT) has been associated with many psychiatric diseases. This study investigated the biodistribution of a serotonin transporter imaging agent, N,N-dimethyl-2-(2-amino-4- 18 F-fluorophenylthio)benzylamine (4-[ 18 F]-ADAM), in nonhuman primate brain using positron emission tomography (PET). Methods: Six and four Macaca cyclopis monkeys were used to determine the transit time (i.e., time necessary to reach biodistribution equilibrium) and the reproducibility of 4-[ 18 F]-ADAM biodistribution in the brain, respectively. The sensitivity and specificity of 4-[ 18 F]-ADAM binding to SERT were evaluated in one monkey challenged with different doses of fluoxetine and one monkey treated with 3,4-methylendioxymethamphetamine (MDMA). Dynamic PET imaging was performed for 3 h after 4-[ 18 F]-ADAM intravenous bolus injection. The specific uptake ratios (SURs) in the midbrain (MB), thalamus (TH), striatum (ST) and frontal cortex (FC) were calculated. Results: The distribution of 4-[ 18 F]-ADAM reached equilibrium 120–150 min after injection. The mean SURs were 2.49±0.13 in MB, 1.59±0.17 in TH, 1.35±0.06 in ST and 0.34±0.03 in FC, and the minimum variability was shown 120–150 min after 4-[ 18 F]-ADAM injection. Using SURs and intraclass coefficient of correlation, the test/retest variability was under 8% and above 0.8, respectively, in SERT-rich areas. Challenge with fluoxetin (0.75–2 mg) dose-dependently inhibited the SURs in various brain regions. 4-[ 18 F]-ADAM binding was markedly reduced in the brain of an MDMA-treated monkey compared to that in brains of normal controls. Conclusion: 4-[ 18 F]-ADAM appears to be a highly selective radioligand for imaging SERT in monkey brain.

F F Sun

Indian Academy of Sciences (India)

Home; Journals; Bulletin of Materials Science. F F Sun. Articles written in Bulletin of Materials Science. Volume 37 Issue 1 February 2014 pp 71-76. Study of electroless copper plating on ABS resin surface modified by heterocyclic organosilane self-assembled film · H N Zhang J Wang F F Sun D Liu H Y Wang F Wang.

29 CFR 2205.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-07-01

...; (3) Specify the schedule for taking the steps necessary to achieve compliance with this section and, if the time period of the transition plan is longer than one year, identify steps that will be taken... Section 2205.150 Labor Regulations Relating to Labor (Continued) OCCUPATIONAL SAFETY AND HEALTH REVIEW...

Investigation into the MgF2-NiF2, CaF2-NiF2, SrF2-NiF2 systems

International Nuclear Information System (INIS)

Ikrami, D.D.; Petrov, S.V.; Fedorov, P.P.; Ol'khovaya, L.A.; Luginina, A.A.; AN SSSR, Moscow. Inst. Fizicheskikh Problem; AN SSSR, Moscow. Inst. Kristallografii)

1984-01-01

Using the methods of differential thermal and X-ray phase analyses the systems MgF 2 -NiF 2 , CaF 2 -NiF 2 , SrF 2 -NiF 2 have been studied. In the system SrF 2 -NiF 2 the only orthorhombic compounds SrNiF 4 (a=14.43; b=3.93; c=5.66 (+-0.01 A)) is formed. SrNiF 4 density constitutes: dsub(X-ray)=4.60+-0.01 g/cm 3 , dsub(exp.)=4.60+-0.03 g/cm 3 . Refraction indices are as follows SrNiF 4 :Ng=1.500; Nsub(m)=1.497; Nsub(p)=1.479. SrNiF 4 magnetic ordering temperature Tsub(N) approximately 100 K

Performance evaluation of a fully depleted monolithic pixel detector chip in 150 nm CMOS technology

Energy Technology Data Exchange (ETDEWEB)

Obermann, Theresa

2017-06-15

The depleted monolithic active pixel sensor (DMAPS) is a new concept integrating full CMOS circuitry onto a (fully) depletable silicon substrate wafer. The realization of prototypes of the DMAPS concept relies on the availability of multiple well CMOS processes and highly resistive substrates. The CMOS foundry ESPROS Photonics offers both and was chosen for prototyping. Two prototypes, EPCB01 and EPCB02, developed in a 150 nm process on a highly resistive n-type wafer of 50 μm thickness, were characterized. The prototypes have 352 square pixels of 40 μm pitch and a small n-well charge collection node with very low capacitance of 5 fF (n{sup +}-implantation size: 5 μm x 5 μm) and about 150 transistors per pixel (CSA and discriminator plus a small digital part). The characterization of the prototypes demonstrates the proof of principle of the concept. Prior to irradiation the prototypes show a signal from a minimum ionizing particle ranging from 2400 e{sup -} to 3000 e{sup -} while the noise is 30 e{sup -} due to the low capacitance. After the irradiation of the prototypes with neutrons up to a fluence of 5 x 10{sup 14} neutrons/cm{sup 2} the performance suffers from the radiation damage leading to a signal of 1000 e{sup -} and a higher noise of 60 e{sup -} due to the increase of the leakage current. The detection efficiency of the prototypes reduces from 94 % to 26 % after the fluence of 5 x 10{sup 14} particles/cm{sup 2}. Due to the small fill factor the detection efficiency shows are strong dependence on the position within the pixel after irradiation. Thus the DMAPS concept with low fill factor can be used for precise vertex reconstruction in High Energy Physics experiments without severe performance loss up to moderate fluences (< 1 x 10{sup 14} particles/cm{sup 2}). The expected particle fluences inside of the volume of the upgrade of the ATLAS pixel detector exceed this limit. However, possible applications could be at future linear collider (ILC or CLIC

47 CFR 90.233 - Base/mobile non-voice operations.

Science.gov (United States)

2010-10-01

... 47 Telecommunication 5 2010-10-01 2010-10-01 false Base/mobile non-voice operations. 90.233... SERVICES PRIVATE LAND MOBILE RADIO SERVICES Non-Voice and Other Specialized Operations § 90.233 Base/mobile non-voice operations. The use of A1D, A2D, F1D, F2D, G1D, or G2D emission may be authorized to base...

Advanced operator interface design for CANDU-3 fuel handling system

Energy Technology Data Exchange (ETDEWEB)

Arapakota, D [Atomic Energy of Canada Ltd., Saskatoon, SK (Canada)

1996-12-31

The Operator Interface for the CANDU 3 Fuel Handling (F/H) System incorporates several improvements over the existing designs. A functionally independent sit-down CRT (cathode-ray tube) based Control Console is provided for the Fuel Handling Operator in the Main Control Room. The Display System makes use of current technology and provides a user friendly operator interface. Regular and emergency control operations can be carried out from this control console. A stand-up control panel is provided as a back-up with limited functionality adequate to put the F/H System in a safe state in case of an unlikely non-availability of the Plant Display System or the F/H Control System`. The system design philosophy, hardware configuration and the advanced display system features are described in this paper The F/H Operator Interface System developed for CANDU 3 can be adapted to CANDU 9 as well as to the existing stations. (author).

Advanced operator interface design for CANDU-3 fuel handling system

International Nuclear Information System (INIS)

Arapakota, D.

1995-01-01

The Operator Interface for the CANDU 3 Fuel Handling (F/H) System incorporates several improvements over the existing designs. A functionally independent sit-down CRT (cathode-ray tube) based Control Console is provided for the Fuel Handling Operator in the Main Control Room. The Display System makes use of current technology and provides a user friendly operator interface. Regular and emergency control operations can be carried out from this control console. A stand-up control panel is provided as a back-up with limited functionality adequate to put the F/H System in a safe state in case of an unlikely non-availability of the Plant Display System or the F/H Control System'. The system design philosophy, hardware configuration and the advanced display system features are described in this paper The F/H Operator Interface System developed for CANDU 3 can be adapted to CANDU 9 as well as to the existing stations. (author)

Full-F gyrofluid model

DEFF Research Database (Denmark)

Madsen, Jens

2013-01-01

variables. The fluid moment hierarchy is closed by approximating the gyrokinetic distribution function as a finite order Hermite-Laguerre polynomial and by determining closure approximations for terms involving the gyrokinetic gyro-averaging operator. The model exactly conserves the gyrokinetic full......A global electromagnetic gyrofluid model based on the full-F gyrokinetic model is derived. The gyrofluid moment variables are not split into fluctuating and equilibrium parts. Profiles are evolved freely, and gyro-averaging operators are not parametrized, but are functions of the gyrofluid moment...

Studies on the properties of poly(ethylene oxide) R-150 water-swollen hydrogel formed by irradiation

International Nuclear Information System (INIS)

Yang Zhanshan; Zhu Nankang; Yang Shuqin; Qiang Yizhong

2000-01-01

The physical and chemical properties of PEO R-150 water-swollen hydrogel films formed by electron beam irradiation are studied and compared with PEO R-150 hydrogel films. The experimental results show that the irradiation dose and mass fraction of the polymer do not produce a significant effect on the gel fraction, of the PEO R-150 water-swollen hydrogel films (P>0.05). The degrees of swelling of the PEO R-150 water-swollen hydrogel films decrease as the irradiation dose increasing (P 0.05). The results indicate that the saturant crosslinking density, the lowest degree of swelling of the PEO R-150 water-swollen hydrogel films produce and unfavorable effect on their machinery strength

Multiband Planar Inverted-F Antenna with Independent Operating Bands Control for Mobile Handset Applications

Directory of Open Access Journals (Sweden)

Mustapha El Halaoui

2017-01-01

Full Text Available A new compact multiband PIFA (Planar Inverted-F Antenna for mobile handset is proposed in this article. The proposed PIFA has a simple geometry with four slots integrated in the radiating patch and ground plane. The PIFA occupies a small volume of 51 × 14 × 7.2 mm3 and is placed on the top portion of mobile phone. The optimized PIFA is worked in the 790 MHz band (737–831 MHz, the 1870 MHz band (1794–1977 MHz, the 2550 MHz band (2507–2615 MHz, and the 3400 MHz band (3341–3545 MHz, to cover LTE700, LTE800, DCS1800, PCS1900, LTE1800, LTE1900, LTE2500, and WIMAX3400 bands. Each of the four operating bands can be controlled independently by the variation of a single parameter of the proposed design, with a wide control range. An omnidirectional radiation pattern to each resonant frequency is obtained with a maximum gain of 2.15 dBi at 790 MHz, 3.99 dBi at 1870 MHz, 4.57 dBi at 2550 MHz, and 6.43 dBi at 3400 MHz. The proposed PIFA is studied in the free space and in the presence of other mobile phone components such as the battery, LCD (liquid crystal display, camera, microphone, speaker, buttons, and a plastic housing. The distribution of specific absorption rate for both European and American standards for each operating band and at various distances between the antenna and the human head is also studied.

17 CFR 150.6 - Responsibility of contract markets.

Science.gov (United States)

2010-04-01

... LIMITS ON POSITIONS § 150.6 Responsibility of contract markets. Nothing in this part shall be construed to affect any provisions of the Act relating to manipulation or corners nor to relieve any contract... 17 Commodity and Securities Exchanges 1 2010-04-01 2010-04-01 false Responsibility of contract...

29 CFR 2706.150 - Program accessibility: Existing facilities.

Science.gov (United States)

2010-07-01

...; (3) Specify the schedule for taking the steps necessary to achieve compliance with this section and, if the time period of the transition plan is longer than one year, identify steps that will be taken... Section 2706.150 Labor Regulations Relating to Labor (Continued) FEDERAL MINE SAFETY AND HEALTH REVIEW...

Labelling of leucocytes with 18 F-FDG

International Nuclear Information System (INIS)

Tomas, M.B.; Tronco, G.G.; Palestro, C.J.

2003-01-01

Full text: Objective: To investigate the effect of blood glucose levels on in-vitro 18 F-FDG labeling of autologous leucocytes. Methods: Seventeen volunteers, 11 men and 6 women, 20 - 54 years old, participated in this study. Using standard techniques, a mixed leucocyte suspension was prepared from 40 ml of blood withdrawn from each volunteer. Blood glucose levels were also measured for each blood sample. After resuspension in 3 ml heparinized saline, the leucocytes were incubated with 11.03 (± 4.48) mCi 18 F-FDG for 30 minutes at 370 C. The labeled cell suspension was then centrifuged for 5 min (150 g). Activity in the cell pellet and supernatant were measured and labelling efficiency calculated. Results: Blood glucose levels ranged from 80 to 178 mg% with a mean of 113 mg%. The overall labelling efficiency was 61.2% (±7.3%). The mean labelling efficiency for blood glucose levels 100 mg%. There is no statistically significant difference between the labeling efficiencies obtained at blood glucose levels 100 mg% (p =0.72). Blood Glucose Level (mg%) Labelling Efficiency (%) 100 61. Conclusion: In summary, no correlation between blood glucose levels and labeling efficiency was observed. Blood glucose levels up to 178 mg% do not affect 18 F-FDG in-vitro labelling of autologous leucocytes. (author)

The effect of HCV Core protein on the expression of miR-150

Directory of Open Access Journals (Sweden)

Sayad Khanizadeh

2016-09-01

Full Text Available Background : Hepatitis C virus (HCV is considered as one of the major pathogenic agents of chronic liver diseases. Previous studies have shown that HCV proteins can interaction with gene regulatory networks such as microRNAs. The aim of this study was to investigate the effect of HCV core protein on the expression of miR-150 in a cell culture model. Materials and Methods: Plasmids expressing full HCV core protein was transfected into Huh7 cell lines while a GFP expressing plasmid employed as negative control. Subsequently, total RNA extracted and Real-Time PCR performed to measure the expression level of miR-150 expression. Moreover, trypan blue exclusion assay was performed to investigate the effect of core protein on cell viability. Results: The gene expression analysis of miR-150 in Huh7 cells showed that endogenous HCV core protein could significantly down regulation of miR-150 when compared to GFP control plasmid and normal cells (P<0.01. Beside, core protein induced no significant proliferative or cytotoxic effects on hepatic cells as determined by trypan blue exclusion assay (P<0.05. Conclusion: Our study suggests that HCV core protein can led to down regulation of miR-150 expression. This data revealed that HCV protein interactions with cell regulatory machinery may contribute to pathogenesis of chronic liver diseases.

Field dispersal ability and taxis to sex pheromone of irradiated F-1 male Asian corn borer

International Nuclear Information System (INIS)

Wang Huasong; Liu Qiongru; Lu Daguang; Wang Endong; Kang Wen; Li Yongjun; He Qiulan; Hu Jianguo

1998-01-01

The dispersal ability of F-1 male Asian corn borer, Ostrinia furnacalis (Guenee), irradiated with 100, 150 and 200 Gy Separately in parental generation were tested by marking (with Calco oil red or Sudan blue internally)-releasing-recapturing (with synthesized sex pheromone) method in the field where the farthest distance from release point to pheromone trap was 550 m. The results showed that, as compared with the normal male moths, despite of the fact that a part of the irradiated F-1 males had lost dispersal ability or taxis to sex pheromone, there was no significant difference between the captured rates of irradiated F-1 males and normal males in the trap 550 m from release point, indicated that the dispersal ability or taxis to sex pheromone of irradiated F-1 males arrived at 550 m from release point are still well matched with the normal ones

ROS (Robot Operating System) für Automotive

OpenAIRE

Bubeck, Alexander

2014-01-01

- Introduction into the Robot Operating System - Open Source in the automotive industries - Application of ROS in the automotive industry - ROS navigation - ROS with real time control - ROS in the embedded world - Outlook: ROS 2.0 - Summary

On the L-characteristic of nonlinear superposition operators in lp-spaces

International Nuclear Information System (INIS)

Dedagic, F.

1995-04-01

In this paper we describe the L-characteristic of the nonlinear superposition operator F(x) f(s,x(s)) between two Banach spaces of functions x from N to R. It was shown that L-characteristic of the nonlinear superposition operator which acts between two Lebesgue spaces has so-called Σ-convexity property. In this paper we show that L-characteristic of the operator F (between two Banach spaces) has the convexity property. It means that the classical interpolation theorem of Reisz-Thorin for a linear operator holds for the nonlinear operator superposition which acts between two Banach spaces of sequences. Moreover, we consider the growth function of the operator superposition in mentioned spaces and we show that one has the logarithmically convexity property. (author). 7 refs

Naturally enhanced ion-line spectra around the equatorial 150-km region

Directory of Open Access Journals (Sweden)

J. L. Chau

2009-03-01

Full Text Available For many years strong radar echoes coming from 140–170 km altitudes at low latitudes have been associated to the existence of field-aligned irregularities (FAIs (the so called 150-km echoes. In this work, we present frequency spectra as well as angular distribution of 150-km echoes. When the 150-km region is observed with beams perpendicular to the magnetic field (B the observed radar spectra are very narrow with spectral widths between 3–12 m/s. On the other hand, when few-degrees off-perpendicular beams are used, the radar spectra are wide with spectral widths comparable to those expected from ion-acoustic waves at these altitudes (>1000 m/s. Moreover the off-perpendicular spectral width increases with increasing altitude. The strength of the received echoes is one to two orders of magnitude stronger than the expected level of waves in thermal equilibrium at these altitudes. Such enhancement is not due to an increase in electron density. Except for the enhancement in power, the spectra characteristics of off-perpendicular and perpendicular echoes are in reasonable agreement with expected incoherent scatter spectra at these angles and altitudes. 150-km echoes are usually observed in narrow layers (2 to 5. Bistatic common volume observations as well as observations made few kilometers apart show that, for most of the layers, there is very high correlation on power fluctuations without a noticeable time separation between simultaneous echoes observed with Off-perpendicular and Perpendicular beams. However, in one of the central layers, the echoes are the strongest in the perpendicular beam and absent or very weak in the off-perpendicular beams, suggesting that they are generated by a plasma instability. Our results indicate that most echoes around 150-km region are not as aspect sensitive as originally thought, and they come from waves that have been enhanced above waves in thermal equilibrium.

Naturally enhanced ion-line spectra around the equatorial 150-km region

Directory of Open Access Journals (Sweden)

J. L. Chau

2009-03-01

Full Text Available For many years strong radar echoes coming from 140–170 km altitudes at low latitudes have been associated to the existence of field-aligned irregularities (FAIs (the so called 150-km echoes. In this work, we present frequency spectra as well as angular distribution of 150-km echoes. When the 150-km region is observed with beams perpendicular to the magnetic field (B the observed radar spectra are very narrow with spectral widths between 3–12 m/s. On the other hand, when few-degrees off-perpendicular beams are used, the radar spectra are wide with spectral widths comparable to those expected from ion-acoustic waves at these altitudes (>1000 m/s. Moreover the off-perpendicular spectral width increases with increasing altitude. The strength of the received echoes is one to two orders of magnitude stronger than the expected level of waves in thermal equilibrium at these altitudes. Such enhancement is not due to an increase in electron density. Except for the enhancement in power, the spectra characteristics of off-perpendicular and perpendicular echoes are in reasonable agreement with expected incoherent scatter spectra at these angles and altitudes. 150-km echoes are usually observed in narrow layers (2 to 5. Bistatic common volume observations as well as observations made few kilometers apart show that, for most of the layers, there is very high correlation on power fluctuations without a noticeable time separation between simultaneous echoes observed with Off-perpendicular and Perpendicular beams. However, in one of the central layers, the echoes are the strongest in the perpendicular beam and absent or very weak in the off-perpendicular beams, suggesting that they are generated by a plasma instability. Our results indicate that most echoes around 150-km region are not as aspect sensitive as originally thought, and they come from waves that have been enhanced above waves in thermal equilibrium.

A new generation of high performance engines for spacecraft propulsion

Science.gov (United States)

Rosenberg, Sanders D.; Schoenman, Leonard

1991-01-01

Experimental data validating advanced engine designs at three thrust levels (5, 15, and 100 lbF) is presented. All of the three engine designs considered employ a Moog bipropellant torque motor valve, platelet injector design, and iridium-lined rhenium combustion chamber. Attention is focused on the performance, robustness, duration, and flexibility characteristics of the engines. It is noted that the 5- and 15-lbF thrust engines can deliver a steady state specific impulse in excess of 310 lbF-sec/lbm at an area ratio of 150:1, while the 150-lbF thrust engines deliver a steady state specific impulse of 320 lbF-sec/lbm at an area ratio of 250:1. The hot-fire test results reveal specific impulse improvements of 15 to 25 sec over conventional fuel film cooled columbium chamber designs while operating at maximum chamber temperatures.

WE-H-207A-04: Impact of Lesion Location On the Repeatability of 18F-NaF PET/CT

Energy Technology Data Exchange (ETDEWEB)

Lin, C; Perk, T; Harmon, S; Perlman, S; Liu, G; Jeraj, R [University of Wisconsin, Madison, WI (United States)

2016-06-15

Purpose: Quantifying the repeatability of imaging biomarkers is critical for assessing therapeutic response. While {sup 18}F-NaF PET/CT has shown to be a repeatable imaging method, research has not shown which factors may influence its repeatability. The purpose of this study was to evaluate whether the location of the lesion impacts the repeatability of quantitative {sup 18}F-NaF PET-derived SUV metrics. Methods: Metastatic castrate-resistant prostate cancer patients with multiple bone lesions received whole-body test-retest NaF PET/CT scans. Malignant bone lesions of PET-defined volume greater than 1.5 cm{sup 3} were identified by a nuclear medicine physician and automatically delineated using a SUV>15 threshold. The maximum (SUVmax), average (SUVmean), and total (SUVtotal) SUV were extracted from each lesion. Atlas-based segmentation was used to divide each patient skeleton into 25 skeletal regions. Test-retest repeatability of each SUV metric was assessed with coefficient of variation (CV). Results: A total of 265 malignant bone lesions from 18 patients were identified by nuclear medicine physician. The largest proportion of bone lesions were localized to the spine (41%), with 41% of those lesions localized to the thoracic spine. One-way ANOVA showed that measurement differences differed significantly for all three metrics across locations (p<0.01 for each metrics). Overall, CV was smallest for SUVmean at 5.3%, followed by SUVmax at 11.5% and SUVtotal at 20.4%. Lesions in the pubis were consistently the most repeatable (CV(SUVmax)= 5.6%, CV(SUVmean)= 0.6%, CV(SUVtotal)= 2.9%). According to SUVmean, repeatability was poorest in the cervical spine (CV = 6.2%), whereas according to SUVmax and SUVtotal, repeatability was poorest in the ribs (CV(SUVmax)= 15.0%, CV(SUVtotal)= 29.8%). Conclusion: Location of the lesion affects the repeatability of {sup 18}F-NaF PET/CT, with the ribs and cervical spine having the lowest repeatability and the pubis having the highest

Railgun accelerators for launching 0.1-g payloads at velocities greater than 150 km/s

International Nuclear Information System (INIS)

Hawke, R.S.

1979-01-01

The promise of an abundant energy supply has inspired many approaches to controlling thermal nuclear fusion. One approach to initiating fusion is to use a hypervelocity projectile to impact a deuterium--tritium (DT) pellet. For this purpose, magnetic accelerators have been propsed for accelerating macroparticles to velocities greater than 100 km/s. This paper summarizes a portion of a study that assesses the feasibility of accelerating a 0.1-g payload to a velocity of 150 km/s or more. In that study it was concluded that magnetic-gradient and railgun accelerators could achieve the goal. The critical factors that limit the design and operation of railgun accelerators are discussed. These factors are combined with a simulation code to assess potential railgun performance in this regime

Laparoscopic Cholecystectomy Under Spinal Anesthesia with Low-Pressure Pneumoperitoneum - Prospective Study of 150 Cases

Directory of Open Access Journals (Sweden)

Sunder Goyal

2012-08-01

Materials and Methods: In a private rural medical college, 150 patients were selected prospectively for laparoscopic cholecystectomy, under low-pressure (8mmHg pneumoperitoneum and under spinal anesthesia over a span of one and a half years. Injection bupivacaine (0.5% was used for spinal anesthesia. All ports were made in a head-down position to avoid hypotension. Shoulder pain was managed by reassurance as well as by diverting the attention and sedation in a few cases. Results: We successfully performed the operations in 145 patients without major complications. Spinal anesthesia was converted to general anesthesia in five patients due to severe shoulder pain. Age varied between 21 and 75 years. Duration of operation time (skin to skin was between 40 and 80 minutes. Twenty-nine patients complained of right shoulder pain. Most of them were managed by reassurance from the anesthetist and a few needed an injection of fentanyl along with midazolam. Conclusion: Laparoscopic cholecystectomy with low-pressure CO2 pneumoperitoneum is feasible and safe under spinal anesthesia. Incidence of postoperative shoulder pain and complications are comparable with laparoscopic cholecystectomy under general anesthesia. [Arch Clin Exp Surg 2012; 1(4.000: 224-228

Eugen Bleuler 150: Bleuler's reception of Freud.

Science.gov (United States)

Dalzell, Thomas G

2007-12-01

On the 150th anniversary of Eugen Bleuler's birth, this article examines his reception of Sigmund Freud and his use of Freudian theory to understand the symptoms of schizophrenia. In addition, in contrast to earlier interpretations of Bleuler's relationship with Freud in terms of an eventual personal and theoretical incompatibility, the article demonstrates that, although Bleuler did distance himself from the psychoanalytic movement, he remained consistent in his views on Freud's theories.

Operator dependent choice of prostate cancer biopsy has limited impact on a gene signature analysis for the highly expressed genes IGFBP3 and F3 in prostate cancer epithelial cells.

Directory of Open Access Journals (Sweden)

Zhuochun Peng

Full Text Available BACKGROUND: Predicting the prognosis of prostate cancer disease through gene expression analysis is receiving increasing interest. In many cases, such analyses are based on formalin-fixed, paraffin embedded (FFPE core needle biopsy material on which Gleason grading for diagnosis has been conducted. Since each patient typically has multiple biopsy samples, and since Gleason grading is an operator dependent procedure known to be difficult, the impact of the operator's choice of biopsy was evaluated. METHODS: Multiple biopsy samples from 43 patients were evaluated using a previously reported gene signature of IGFBP3, F3 and VGLL3 with potential prognostic value in estimating overall survival at diagnosis of prostate cancer. A four multiplex one-step qRT-PCR test kit, designed and optimized for measuring the signature in FFPE core needle biopsy samples was used. Concordance of gene expression levels between primary and secondary Gleason tumor patterns, as well as benign tissue specimens, was analyzed. RESULTS: The gene expression levels of IGFBP3 and F3 in prostate cancer epithelial cell-containing tissue representing the primary and secondary Gleason patterns were high and consistent, while the low expressed VGLL3 showed more variation in its expression levels. CONCLUSION: The assessment of IGFBP3 and F3 gene expression levels in prostate cancer tissue is independent of Gleason patterns, meaning that the impact of operator's choice of biopsy is low.

29 CFR 780.150 - Scope and limits of “preparation for market.”

Science.gov (United States)

2010-07-01

... 29 Labor 3 2010-07-01 2010-07-01 false Scope and limits of âpreparation for market.â 780.150... STANDARDS ACT General Scope of Agriculture Preparation for Market § 780.150 Scope and limits of “preparation for market.” “Preparation for market” is also named as one of the practices which may be included in...

Tartu füüsikud põrgatavad ilmapalli ehk Õhupallid koolifüüsikas / Piia Post, Kristel Uiboupin

Index Scriptorium Estoniae

Post, Piia, 1963-

2016-01-01

Möödunud aastal tähistati 150 aasta möödumist professionaalse ilmavaatluse algusest Eestis. Selle tähistamiseks avati uus ilmajaam Tartu ülikooli füüsikahoone ehk Physicumi katusel. Selle heeliumiga täidetud õhupalliga võeti osa rahvusvahelisest õhupallide lennutamise võistlusest „Global Space Balloon Challenge”

An intravaginal ring that releases the NNRTI MIV-150 reduces SHIV transmission in macaques.

Science.gov (United States)

Singer, Rachel; Mawson, Paul; Derby, Nina; Rodriguez, Aixa; Kizima, Larisa; Menon, Radhika; Goldman, Daniel; Kenney, Jessica; Aravantinou, Meropi; Seidor, Samantha; Gettie, Agegnehu; Blanchard, James; Piatak, Michael; Lifson, Jeffrey D; Fernández-Romero, José A; Robbiani, Melissa; Zydowsky, Thomas M

2012-09-05

Microbicides may prevent HIV and sexually transmitted infections (STIs) in women; however, determining the optimal means of delivery of active pharmaceutical ingredients remains a major challenge. We previously demonstrated that a vaginal gel containing the non-nucleoside reverse transcriptase inhibitor MIV-150 partially protected macaques from SHIV-RT (simian/HIV reverse transcriptase) infection, and the addition of zinc acetate rendered the gel significantly protective. We test the activity of MIV-150 without the addition of zinc acetate when delivered from either ethylene vinyl acetate (EVA) or silicone intravaginal rings (IVRs). MIV-150 was successfully delivered, because it was detected in vaginal fluids and tissues by radioimmunoassay in pharmacokinetic studies. Moreover, EVA IVRs significantly protected macaques from SHIV-RT infection. Our results demonstrate that MIV-150-containing IVRs have the potential to prevent HIV infection and highlight the possible use of IVRs for delivering drugs that block HIV and other STIs.

The O(αs3) massive operator matrix elements of O(nf) for the structure function F2(x,Q2) and transversity

International Nuclear Information System (INIS)

Ablinger, J.; Bluemlein, J.; Klein, S.; Schneider, C.; Wissbrock, F.

2011-01-01

The contributions ∝n f to the O(α s 3 ) massive operator matrix elements describing the heavy flavor Wilson coefficients in the limit Q 2 >>m 2 are computed for the structure function F 2 (x,Q 2 ) and transversity for general values of the Mellin variable N. Here, for two matrix elements, A qq,Q PS (N) and A qg,Q (N), the complete result is obtained. A first independent computation of the contributions to the 3-loop anomalous dimensions γ qg (N), γ qq PS (N), and γ qq NS,(TR) (N) is given. In the computation advanced summation technologies for nested sums over products of hypergeometric terms with harmonic sums have been used. For intermediary results generalized harmonic sums occur, while the final results can be expressed by nested harmonic sums only.

Bioequivalence of fixed-dose combination RIN®-150 to each reference drug in loose combination.

Science.gov (United States)

Wang, H F; Wang, R; O'Gorman, M; Crownover, P; Damle, B

2015-03-01

RIN(®)-150 is a fixed-dose combination (FDC) tablet containing rifampicin (RMP, 150 mg) and isoniazid (INH, 75 mg) developed for the treatment of tuberculosis. This study was conducted at a single center: the Pfizer Clinical Research Unit in Singapore. To demonstrate bioequivalence of each drug component between RIN-150 and individual products in a loose combination. This was a randomized, open-label, single-dose, two-way crossover study. Subjects received single doses of RIN-150 or two individual reference products under fasting conditions in a crossover fashion, with at least 7 days washout between doses. The primary measures for comparison were peak plasma concentration (Cmax) and the area under plasma concentration-time curve (AUC). Of 28 subjects enrolled, 26 completed the study. The adjusted geometric mean ratios of Cmax and AUClast between the FDC and single-drug references and 90% confidence intervals were respectively 91.63% (90%CI 83.13-101.01) and 95.45% (90%CI 92.07-98.94) for RMP, and 107.58% (90%CI 96.07-120.47) and 103.45% (90%CI 99.33-107.75) for INH. Both formulations were generally well tolerated in this study. The RIN-150 FDC tablet formulation is bioequivalent to the two single-drug references for RMP and INH at equivalent doses.

Computing the forgotten topological index of four operations on graphs

Directory of Open Access Journals (Sweden)

Shehnaz Akhter

2017-04-01

The first and second Zagreb indices for the four operations on graphs were studied by Deng et al. (2016. In this paper, we extend this study to the F-index of graphs and determine the closed formulas for the F-index of four operations on graphs.

ADS based on NaF-PbF2 molten salt

International Nuclear Information System (INIS)

Volk, V.I.; Vakhrushin, A.Yu.; Kwaratzkheli, A.Yu.; Konev, V.N.; Kochurov, B.P.; Shvedov, O.V.

1999-01-01

The neutron-physical parameters of an accelerator driven system (ADS) with a proton accelerator feeding a sub-critical molten salt blanket are investigated. The installation is designed for the production of electric power, involving thorium in a fuel cycle, transmutation of fission products and actinides. It is supposed to use fluoride salt composition 66PbF 2 -34NaF with addition of heavy elements (Th, Np, Pu and minor actinides) as the material of fuel, coolant and target. The thermal power of this ADS is 2000 MW. The current of the 1 GeV proton beam is 29 mA. The investigations are carried out for the following fuel cycles: the plutonium one, the burning of Np and minor actinides and the plutonium-thorium cycle. The balances of nuclides systems under supposition of its continuous operation during 20 years are presented [ru

Carter : Iisraelil on 150 või enam tuumapommi / Kaivo Kopli

Index Scriptorium Estoniae

Kopli, Kaivo

2008-01-01

USA endine president Jimmy Carter väitis, et Iisraelil on 150 tuumapommi või rohkemgi. Eri hinnangutest Iisraeli tuumapommide arvu kohta, n.-ö. tunnustatud tuumariigid maailmas. Lisa: Tuumakatsetus 1979. aastal?

Exact coefficients for higher dimensional operators with sixteen supersymmetries

Energy Technology Data Exchange (ETDEWEB)

Chen, Wei-Ming [Department of Physics and Astronomy, National Taiwan University,Taipei 10617, Taiwan, R.O.C. (China); Huang, Yu-tin [Department of Physics and Astronomy, National Taiwan University,Taipei 10617, Taiwan, R.O.C. (China); School of Natural Sciences, Institute for Advanced Study,Princeton, NJ 08540 (United States); Wen, Congkao [INFN Sezione di Roma “Tor Vergata' ,Via della Ricerca Scientifica, 00133 Roma (Italy)

2015-09-15

We consider constraints on higher-dimensional operators for supersymmetric effective field theories. In four dimensions with maximal supersymmetry and SU(4) R-symmetry, we demonstrate that the coefficients of abelian operators F{sup n} with MHV helicity configurations must satisfy a recursion relation, and are completely determined by that of F{sup 4}. As the F{sup 4} coefficient is known to be one-loop exact, this allows us to derive exact coefficients for all such operators. We also argue that the results are consistent with the SL(2,Z) duality symmetry. Breaking SU(4) to Sp(4), in anticipation for the Coulomb branch effective action, we again find an infinite class of operators whose coefficients are determined exactly. We also consider three-dimensional N=8 as well as six-dimensional N=(2,0),(1,0) and (1,1) theories. In all cases, we demonstrate that the coefficient of dimension-six operator must be proportional to the square of that of dimension-four.

Pulsed and cw laser oscillations in LiF:F-2 color center crystal under laser diode pumping.

Science.gov (United States)

Basiev, Tasoltan T; Vassiliev, Sergey V; Konjushkin, Vasily A; Gapontsev, Valentin P

2006-07-15

Continuous-wave laser oscillations in LiF:F-2 crystal optically pumped by a laser diode at 970 nm were demonstrated for what is believed to be the first time. The slope efficiency of 14% and conversion efficiency of 5.5% were achieved for 80 micros pump pulse duration and 5 Hz pulse repetition rate. An efficiency twice as low was measured at a 6.25 kHz pulse repetition rate (50% off-duty factor) and in cw mode of laser operation.

Removal design report for the 108-F Biological Laboratory

Energy Technology Data Exchange (ETDEWEB)

NONE

1997-09-01

Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m{sup 2} (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal.

Removal design report for the 108-F Biological Laboratory

International Nuclear Information System (INIS)

1997-09-01

Most of the 100-F facilities were deactivated with the reactor and have since been demolished. Of the dozen or so reactor-related structures, only the 105-F Reactor Building and the 108-F Biology Laboratory remain standing today. The 108-F Biology Laboratory was intended to be used as a facility for the mixing and addition of chemicals used in the treatment of the reactor cooling water. Shortly after F Reactor began operation, it was determined that the facility was not needed for this purpose. In 1949, the building was converted for use as a biological laboratory. In 1962, the lab was expanded by adding a three-story annex to the original four-story structure. The resulting lab had a floor area of approximately 2,883 m 2 (main building and annex) that operated until 1973. The building contained 47 laboratories, a number of small offices, a conference room, administrative section, lunch and locker rooms, and a heavily shielded, high-energy exposure cell. The purpose of this removal design report is to establish the methods of decontamination and decommissioning and the supporting functions associated with facility removal and disposal

Superresolution beams

CSIR Research Space (South Africa)

Ngcobo, S

2012-07-01

Full Text Available Tested the concept on an Nd:YAG system ? CSIR 2011 www.csir.co.za r = ? R = 98% DOE r = 300 mm HR Nd:YAG C C D Pump f = 150 mm f = 150 mm f = 25 mm f = 150 mm Aperture Slide 9 Tested the concept on an Nd... mode? ? Test: Fourier Transform of LGB is a LGB ? CSIR 2011 www.csir.co.za r = ? R = 98%DOE r = 300 mm HR Nd:YAG CC D Pump f = 150 mm f = 150 mm f = 25 mm f = 150 mm CC D r = ? R = 98%DOE r = 300 mm HR Nd...

Multi-kiloampere, electron-beam generation using metal photo-cathodes driven by ArF and KrF lasers

Energy Technology Data Exchange (ETDEWEB)

Carlson, R L; Moya, S S; Ridlon, R N; Seitz, G J; Shurter, R P [Los Alamos Natl. Lab., Los Alamos, NM (United States)

1997-12-31

An electron-beam-pumped laser operating at ArF (193 nm) or KrF (248 nm) producing 35 MW (3.5 J in 100 ns) has been used to illuminate a micro-machined aluminum cathode. The cathode was pulsed to 2.75 MV at fields of 185 kV/cm (15-cm AK gap) using REX (a 4-MV, 5-kA, 85-ns) pulsed-diode machine. The extracted current versus incident laser power (the quantum efficiency) was measured for KrF at 5x10{sup -5} and for ArF which was significantly higher at 1x10{sup -3}. Current densities of 100 A/cm{sup 2} and total currents of 2 kA have been achieved, the latter by increasing the cathode area in proportion to the laser power. (author). 8 figs., 14 refs.

Post-void residual urine under 150 ml does not exclude voiding dysfunction in women

DEFF Research Database (Denmark)

Khayyami, Yasmine; Klarskov, Niels; Lose, Gunnar

2016-01-01

INTRODUCTION AND HYPOTHESIS: It has been claimed that post-void residual urine (PVR) below 150 ml rules out voiding dysfunction in women with stress urinary incontinence (SUI) and provides license to perform sling surgery. The cut-off of 150 ml seems arbitrary, not evidence-based, and so we sough...

Effects of tramadol or morphine in dogs undergoing castration on intra-operative electroencephalogram responses and post-operative pain.

Science.gov (United States)

Kongara, K; Chambers, J P; Johnson, C B; Dukkipati, V S R

2013-11-01

To compare the effects of pre-operatively administered tramadol with those of morphine on electroencephalographic responses to surgery and post-operative pain in dogs undergoing castration. Dogs undergoing castration were treated with either pre-operative morphine (0.5 mg/kg S/C, n = 8) or tramadol (3 mg/kg S/C, n = 8). All dogs also received 0.05 mg/kg acepromazine and 0.04 mg/kg atropine S/C in addition to the test analgesic. Anaesthesia was induced with thiopentone administered I/V to effect and maintained with halothane in oxygen. Respiratory rate, heart rate, end-tidal halothane tension (EtHal) and end-tidal CO2 tension (EtCO2) were monitored throughout surgery. Electroencephalograms (EEG) were recorded continuously using a three electrode montage. Median frequency (F50), total power (Ptot) and 95% spectral edge frequency (F95) derived from EEG power spectra recorded before skin incision (baseline) were compared with those recorded during ligation of the spermatic cords of both testicles. Post-operatively, pain was assessed after 1, 3, 6 and 9 h using the short form of the Glasgow composite measure pain scale (CMPS-SF). Dogs premedicated with tramadol had higher mean F50 (12.2 (SD 0.2) Hz) and lower Ptot (130.39 (SD 12.1) µv(2)) compared with those premedicated with morphine (11.5 (SD 0.2) Hz and 161.8 (SD 15.1) µv(2), respectively; p0.05). The F95 of the EEG did not differ between the two groups during the ligation of either testicle (p > 0.05). Post-operatively, no significant differences in the CMPS-SF score were found between animals premedicated with tramadol and morphine at any time during the post-operative period. No dog required rescue analgesia. Tramadol and morphine administered pre-operatively provided a similar degree of post-operative analgesia in male dogs at the doses tested.

Evaluation of gross tumor size using CT, 18F-FDG PET, integrated 18F-FDG PET/CT and pathological analysis in non-small cell lung cancer

International Nuclear Information System (INIS)

Yu Huiming; Liu Yunfang; Hou Ming; Liu Jie; Li Xiaonan; Yu Jinming

2009-01-01

Purpose: The correlation of gross tumor sizes between combined 18 F-FDG PET/CT images and macroscopic surgical samples has not yet been studied in detail. In the present study, we compared CT, 18 F-FDG PET and combined 18 F-FDG PET/CT for the delineation of gross tumor volume (GTV) and validated the results through examination of the macroscopic surgical specimen. Methods: Fifty-two operable non-small cell lung cancer (NSCLC) patients had integrated 18 F-FDG PET/CT scans preoperatively and pathological examination post-operation. Four separate maximal tumor sizes at X (lateral direction), Y (ventro-dorsal direction) and Z (cranio-caudal direction) axis were measured on 18 F-FDG PET, CT, combined 18 F-FDG PET/CT and surgical specimen, respectively. Linear regression was calculated for each of the three imaging measurements versus pathological measurement. Results: No significant differences were observed among the tumor sizes measured by three images and pathological method. Compared with pathological measurement, CT size at X, Y, Z axis was larger, whereas combined 18 F-FDG PET/CT and 18 F-FDG PET size were smaller. Combined 18 F-FDG PET/CT size was more similar to the pathological size than that of 18 F-FDG PET or CT. Results of linear regressions showed that integrated 18 F-FDG PET/CT was the most accurate modality in measuring the size of cancer. Conclusions: 18 F-FDG PET/CT correlates more faithfully with pathological findings than 18 F-FDG PET or CT. Integrated 18 F-FDG PET/CT is an effective tool to define the target of GTV in radiotherapy.

Preliminary results from a study of the double beta decay of 150Nd

International Nuclear Information System (INIS)

Perillo, I.M.C.; Chan, Y.D.; Hurley, D.; Lesko, K.T.; McDonald, R.J.; Moorhead, M.E.; Norman, E.B.; Smith, A.R.; Stokstad, R.G.

1996-01-01

We report the preliminary results from a study of the double beta decay of 150 Nd to the first 0 + excited state of 150 Sm. Our data consists of 50 days of counting 5 kg of natural Nd 2 O 3 at the LBNL-Oroville low background facility. The deduced lower limit for the half life of this decay mode is 4.9.10 19 years. (orig.)

An Evaluation of Theraphy with Fluconazole 150 mg Tablets Compared to Fluconazole 150 mg Tablets Plus Dermoxen Lenitiva Cream in The Time to Reduce Simptomatology in Women with Vulvovaginal Candidiasis

Directory of Open Access Journals (Sweden)

Davide Carati

2014-06-01

Full Text Available Aim of the study. Authors investigated first of all the time to onset of first relief of symptoms. Secondary measures included the time to overall relief of symptoms and the reoccurrence rate over the first 45 days after the first visit. Methods. A randomized, open-label, parallel study evaluated 47 women with moderate to severe symptoms of Vulvo Vaginal Candidiasis (VVC. Patients were divided into two groups of treatment: group 1 followed a therapy with Fluconazole 150 mg tablets, while group 2 had a therapy based on Fluconazole 150 mg tablets coadjuvated by Dermoxen Lenitiva cream. Results. The time at which 50% of patients experienced first relief of symptoms was 24.6 hours for Group 1, while for Group 2 it was 12.4 hours (P<0.05. There were significant differences between the two groups in respect to the time of first relief of symptoms and reoccurrence of infection within 45 days of treatment. Conclusions. Combined treatment with Fluconazole 150 mg tablets and by Dermoxen Lenitiva cream provides statistically significant improvement in the time of first relief of symptoms, complete relief of symptoms and relapse time in the treatment of VVC compared to fluconazole 150 mg tablets only.

13 CFR 108.150 - Management and ownership diversity requirement.

Science.gov (United States)

2010-01-01

... VENTURE CAPITAL (âNMVCâ) PROGRAM Qualifications for the NMVC Program Organizing A Nmvc Company § 108.150... 70 percent of your Regulatory Capital or your Leverageable Capital. (c) Non-affiliation requirement. At least 30 percent of your Regulatory Capital and Leverageable Capital must be owned and controlled...

Study of the hadronic production of J/psi and T resonances from 150 to 280 GeV

International Nuclear Information System (INIS)

Charpentier, P.

1984-02-01

We have studied in a very high statistics experiment the production of the J/psi resonance by hadron beams (π +- , K +- , p, anti-p) of 150, 200 and 280 GeV. By comparison of the differential cross-sections dσ/dxsub(F) between our two targets (H 2 and platinum). We have shown that about 20% of the J/psi's are produced by a diffractive mechanism. The study of the 80% produced through a hard process has been done in the framework of a parton fusion model in order to extract the gluon structure functions in both the nucleon and the pion. We have also made a comparison between different hadrons for the production cross-section as well as for the differential cross-section. Finally, the production cross-section of T by pions has been measured at our three energies. Pions are found to be about 30 times more efficient than protons in producing T's [fr

miR-150 suppresses the proliferation and tumorigenicity of leukemia stem cells by targeting the Nanog signaling pathway

Directory of Open Access Journals (Sweden)

Dan-dan Xu

2016-11-01

Full Text Available Proliferation, a key feature of cancer cells, accounts for the majority of cancer-related diseases resulting in mortality. MicroRNAs (miRNAs plays important post-transcriptional modulation roles by acting on multiple signaling pathways, but the underlying mechanism in proliferation and tumorigenicity is unclear. Here, we identified the role of miR-150 in proliferation and tumorigenicity in leukemia stem cells (LSCs (CD34+CD38- cells. miR-150 expression was significantly down-regulated in LSCs from leukemia cell lines and clinical samples. Functional assays demonstrated that increased miR-150 expression inhibited proliferation and clonal and clonogenic growth, enhanced chemosensitivity, and attenuated tumorigenic activity of LSCs in vitro. Transplantation animal studies revealed that miR-150 overexpression progressively abrogates tumour growth. Immunohistochemistry assays demonstrated that miR-150 overexpression enhanced caspase-3 level and reduced Ki-67 level. Moreover, luciferase reporter assays indicated Nanog is a direct and functional target of miR-150. Nanog silencing using small interfering RNA recapitulated anti-proliferation and tumorigenicity inhibition effects. Furthermore, miR-150 directly down-regulated the expression of other cancer stem cell factors including Notch2 and CTNNB1. These results provide insights into the specific biological behaviour of miR-150 in regulating LSC proliferation and tumorigenicity. Targeting this miR-150/Nanog axis would be a helpful therapeutic strategy to treat acute myeloid leukemia.

Cleanup Verification Package for the 118-F-6 Burial Ground

International Nuclear Information System (INIS)

Sulloway, H.M.

2008-01-01

This cleanup verification package documents completion of remedial action for the 118-F-6 Burial Ground located in the 100-FR-2 Operable Unit of the 100-F Area on the Hanford Site. The trenches received waste from the 100-F Experimental Animal Farm, including animal manure, animal carcasses, laboratory waste, plastic, cardboard, metal, and concrete debris as well as a railroad tank car

CD150 is a member of a family of genes that encode glycoproteins on the surface of hematopoietic cells.

Science.gov (United States)

Wang, N; Morra, M; Wu, C; Gullo, C; Howie, D; Coyle, T; Engel, P; Terhorst, C

2001-07-01

Human CD150 (SLAM) is a glycoprotein expressed on the surface of T, B, natural killer, and dendritic cells. The extracellular domain of CD150 is the receptor for measles virus and CD150 acts as a co-activator on T and B cells. We characterized the mouse and human CD150 genes, each of which comprises seven exons spanning approximately 32 kb. Mouse CD150 mRNA was detected in T cells and in most thymocyte subsets, except CD4-8- cells. Surprisingly, the CD4-8- thymocytes of CD3gammadeltanull mice, but not of Ragnull or severe combined immunodeficiency mice, expressed CD150. Whereas high levels of CD150 were found in Th1 cells, only small amounts were detectable in Th2 cells. CD150 expression was up-regulated upon in vitro activation of mouse T cells by anti-CD3. The complete mouse CD150 gene is highly homologous to its human orthologue in terms of nucleotide sequences and intron/exon organization. The human genomic sequences indicate that all isoforms detected so far have arisen from alternative splicing events. As judged by fluorescence in situ hybridization, mouse CD150 mapped to Chromosome (Chr) 1, band 1H2.2-2.3, and human CD150 was found on Chr 1q22. Human and mouse CD150 share sequence homologies with six other genes, five of which - CD84, CD229 (Ly-9), CD244 (2B4), CD48, and 19A - are localized in a 250-kb segment in close proximity to the human gene. Their location and their sequence similarities strongly suggest that the CD150 family of cell surface receptors arose via successive duplications of a common ancestral gene.

12 CFR 551.150 - How do my officers and employees file reports of personal securities trading transactions?

Science.gov (United States)

2010-01-01

... of personal securities trading transactions? 551.150 Section 551.150 Banks and Banking OFFICE OF... TRANSACTIONS Securities Trading Policies and Procedures § 551.150 How do my officers and employees file reports of personal securities trading transactions? An officer or employee described in § 551.140(d) must...

The p150 subunit of CAF-1 causes association of SUMO2/3 with the DNA replication foci

International Nuclear Information System (INIS)

Uwada, Junsuke; Tanaka, Niina; Yamaguchi, Yutaro; Uchimura, Yasuhiro; Shibahara, Kei-ichi; Nakao, Mitsuyoshi; Saitoh, Hisato

2010-01-01

The small ubiquitin-related modifier 2/3 (SUMO2/3) can be post-translationally conjugated to a wide variety of proteins constituting chromatin, the platform for genetic and epigenetic regulation. Nevertheless, it is unclear how SUMO2/3 and SUMO2/3-modified proteins are delivered to the chromatin fibers. Here we report that the largest subunit of chromatin assembly factor 1 (CAF-1), human p150, interacts directly and preferentially with SUMO2/3. Amino acid residue of 98-105 in p150 is essential and sufficient for SUMO2/3 interaction. p150-SUMO2/3 interaction coincided with regions that replicate chromatin fibers, because accumulation of the proliferating cell nuclear antigen (PCNA), and incorporation of bromodeoxyuridine (BrdU) were detected at foci co-localized with both p150 and SUMO2/3 during the S-phase in a cell line expressing epitope-tagged p150. Although inhibition of SUMO2/3 expression had only a small effect on p150 deposition on the replication sites, depletion of p150 led to delocalization of SUMO2/3 from the replication foci. Furthermore, p150 mutants deficient in SUMO2/3 interaction, caused a major reduction of SUMO2/3 at the replication foci. Thus, our findings suggest an expanded role of p150 as a SUMO2/3-interacting factor, and raise the intriguing possibility that p150 plays a role in promoting delivery of SUMO2/3 or SUMO2/3-modified proteins (or both) on chromatin fibers during replication.

150 years of Freud-Kraepelin dualism.

Science.gov (United States)

Trede, Katharina

2007-09-01

The year 2006 marked the 150th Birthday of Emil Kraepelin and Sigmund Freud. Kraepelin and Freud were two very different yet very similar men. The comparison between their biographies shows many parallels in their lives and personalities. They were, in their time, the two most influential individuals in psychiatry. They wrote and thought about similar topics in the field yet came to quite different conclusions. Both did not show public respect for each other but wrote about the importance of integrating their respective approaches into the study of the mind/brain problem. Psychiatry today continues to struggle with the integration of the biological and psychodynamic approach.

Design and operation of gas-heated thermal pumping units

Energy Technology Data Exchange (ETDEWEB)

Rostek, H A [Ruhrgas A.G., Essen (Germany, F.R.)

1979-03-01

The first gas heat pump systems have been operated since spring 1977. These are applied in living houses, school, swimming pools, and sport places and administration buildings. The heating performance of these systems is 150-3800 kW. Two of these systems, one in a swimming pool and one in a house for several families are operating, each of them for one heating period. The operational experiences with these gas heat pumps are reported on, basing on measurement results. The experience gathered from the operation of gas heat pumps systems is applied to the planning of other plants. The development of a standardized gas heat pump-series is emphasized.

Superdeformation studies in {sup 150}Tb and {sup 153}Ho

Energy Technology Data Exchange (ETDEWEB)

Nisius, D.; Janssens, R.V.F.; Crowell, B. [and others

1995-08-01

There are now over 40 superdeformed (SD) bands known in the A {approximately} 150 region and in most cases the properties of these bands are understood in terms of single-particle excitations in the absence of pairing. By continuing the search for new SD bands we hope to gain insight into (1) the ordering of the proton and neutron orbitals near the Fermi surface in the SD well, (2) the effects that the alignment of those orbitals has on the moments of inertia, and (3) the collective excitations in the SD well. For {sup 150}Tb, which is one proton and one neutron away from the SD doubly-magic nucleus {sup 152}Dy, it should be possible to study SD bands based on both proton and neutron hole excitations. By adding one proton to the {sup 152}Dy nucleus (i.e. {sup 153}Ho) proton excitations above the Z = 66 shell gap can be studied. These excitations are important as calculations suggested that the proton intruder orbital N = 7 might become occupied. Interactions between this orbital and a N = 5 level may result in softness towards octupole vibrations. High spin states in {sup 150}Th and {sup 153}Ho were populated using the {sup 124}Sn({sup 31}P,5n) and {sup 120}Sn({sup 37}Cl,4n) reactions, respectively. In both cases the early implementation phase of Gammasphere was used to detect the decay gamma rays and over 1 x 10{sup 9} triple and higher fold coincidence events were recorded. In {sup 150}Tb, the data analysis is complete and two new SD bands were identified. The fact that Im{sup (2)} moments of inertia are sensitive to the specific high-N intruder content of the SD bands was used to suggest configurations for the two new bands. A paper reporting these results is being prepared. For {sup 153}Ho, data analysis is still in its early stages.

Assessment of the thermodynamic behavior of neptunium in water and model groundwaters from 25 to 150/sup 0/C

Energy Technology Data Exchange (ETDEWEB)

Lemire, R J

1984-03-15

Standard molal Gibbs energy of formation and entropy data for simple neptunium solids and aqueous neptunium complexes with OH/sup -/, Cl/sup -/, F/sup -/, CO/sub 3//sup 2 -/, PO/sub 4//sup 3 -/, SO/sub 4//sup 2 -/ and Na/sup +/ have been critically reviewed. Selected values are used with estimated heat capacity values to derive self-consistent analytical expressions for the temperature dependence of the standard molal Gibbs energies of formation of the species from 25 to 150/sup 0/C. The Gibbs energies have been used to evaluate the effect of different concentrations of ligands on the solubility of neptunium solids as a function of temperature. Potential-pH diagrams are given for neptunium in pure water and in two model groundwaters. Important deficiencies in the available thermodynamic data for neptunium species are discussed. 90 references, 12 figures, 6 tables.

Analysis And Simulation Of Low Profile Planar Inverted - F Antenna Design For WLAN Operation In Portable Devices

Directory of Open Access Journals (Sweden)

Zaw Htet Lwin

2015-08-01

Full Text Available This paper presents a compact planar invertedF antenna PIFA design for WLAN operation in portable devices. The proposed design has size of 8 x 21 mm and provides peak directive gain of 5.78dBi with the peak return loss of -33.89dB and input impedance of 50.28amp8486. It covers a 10dB return loss bandwidth of 410MHz 2.37GHz 2.789GHz. Its VSWR varies from 1.96 to 1.93 within the antenna return loss bandwidth. As the dimension of the proposed antenna is very small the antenna is promising to be embedded within the different portable devices employing WiFi applications. This paper includes the return loss as a function of frequency with varying the different parameters VSWR input resistance radiation pattern and current distribution of the proposed antenna.

Study of mixed programming gamma spectrum acquisition method based on MSP430F4618

International Nuclear Information System (INIS)

Li Yuezhong; Tang Bin; Zhang Zhongliang; Xie Xiaolin

2012-01-01

In order to reduce the hand-held gamma spectrometer measurements dead time and to complete the low-voltage and low-power design, the spectrum signal acquisition circuit is constituted by the ultra-low power microcontroller MSP430F4618 and its external signal conditioning circuit, anti-coincidence circuit interface and its on-chip sample hold and A/D converter. C language programming and assembly one have been used together. The sample hold and A/D conversion and spectrum acquisition programming is accomplished by assembly language, and the system monitoring and task scheduler designing is accomplished by C language programming. The handhold gamma spectrometer power supply, which just uses two No.5 rechargeable batteries, is designed by high-efficiency DC-DC circuit. The prototype gamma spectrometer is developed by the method, and its testing shows that the implementation of spectrum acquisition time is shorten by twice to 3 times, that is, the dead measurement can be reduced; and the machine operating current does not exceed 150 mA. By using two 2400 mAh No.5 rechargeable battery, the machine can work continuously more than 10 hours, and it can meet the application requirements. (authors)

Low carbohydrate diet before 18F-FDG tumor imaging contributes to reduce myocardial 18F-FDG uptake

International Nuclear Information System (INIS)

Miao Weibing; Chen Shaoming; Zheng Shan; Wu Jing; Peng Jiequan; Jiang Zhihong

2014-01-01

Objective: To evaluate whether low carbohydrate diet before 18 F-FDG tumor imaging could reduce myocardial 18 F-FDG uptake. Methods: From April 2011 to January 2012, 70 patients were enrolled in this study.They were randomly divided into control group (34 cases) and test group (36 cases). Patients in control group were on regular diet, while those in test group had low carbohydrate diet in the evening before imaging. Blood samples were taken before injection of 18 F-FDG for the measurement of serum glucose, free fatty acid,insulin and ketone body. Whole body 18 F-FDG tomography was performed with dual-head coincidence SPECT. The myocardial uptake of FDG was assessed visually and scored as 0 for no uptake, 1 for uptake lower than liver, 2 for uptake similar to liver, 3 for uptake higher than liver, and 4 for remarkable uptake.The ratio of myocardium to liver (H/L) was calculated. Two-sample t test, Wilcoxon rank sum test and linear correlation analysis were performed. Results: The myocardial uptake in test group was significantly lower than that in control group with H/L ratios of 0.94±0.57 and 1.50±1.04, respectively (t=-2.75, P<0.05). The concentrations of serum free fatty acid and ketone body in test group were significantly higher than those in control group: (0.671±0.229) mmol/L vs (0.547±0.207) mmol/L and (0.88±0.60) mmol/L vs (0.57±0.32) mmol/L, t=2.38 and 2.67, both P<0.05. The concentrations of glucose and insulin were (5.28±1.06) mmol/L and (35.16±33.70) pmol/L in test group, which showed no significant difference with those in control group ((5.19±0.78) mmol/L and (41.64±35.13) pmol/L, t=0.39 and-0.79, both P>0.05). A negative correlation was found between the myocardial uptake of 18 F-FDG and serum free fatty acid/ketone body concentration (r=-0.40, -0.33, both P<0.01), respectively. There was no correlation between the myocardial uptake of 18 F-FDG and glucose/insulin (r=-0.02, 0.13, both P>0.05), respectively. Conclusion: Low carbohydrate

14 CFR 1260.150 - Purpose of reports and records.

Science.gov (United States)

2010-01-01

... Purpose of reports and records. Sections 1260.151 through 1260.153 set forth the procedures for monitoring and reporting on the recipient's financial and program performance and the necessary standard... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Purpose of reports and records. 1260.150...

A multi-centre phase 3 study comparing efficacy and safety of Bemfola® versus Gonal-f® in women undergoing ovarian stimulation for IVF

DEFF Research Database (Denmark)

Rettenbacher, M; Andersen, A N; Garcia-Velasco, J A

2015-01-01

injection (n = 372) showed Bemfola yielding similar efficacy and safety profiles to Gonal-f. Women aged 20-38 years of age were randomized 2:1 to receive a single, daily, subcutaneous 150 IU dose of either Bemfola or Gonal-f. This study tested equivalence in the number of retrieved oocytes using a pre......Bemfola (follitropin alfa) (Finox AG, Switzerland), a new recombinant FSH, has a comparable pharmacological profile to that of Gonal-f (Merck Serono, Germany), the current standard for ovarian stimulation. A randomized, multi-centre, Phase 3 study in women undergoing IVF or intracytoplasmic sperm...

Reactor operation method

International Nuclear Information System (INIS)

Osumi, Katsumi; Miki, Minoru.

1979-01-01

Purpose: To prevent stress corrosion cracks by decreasing the dissolved oxygen and hydrogen peroxide concentrations in the coolants within a reactor container upon transient operation such as at the start-up or shutdown of bwr type reactors. Method: After a condensate has been evacuated, deaeration operation is conducted while opening a main steam drain line, as well as a main steam separation valve and a by-pass valve in a turbine by-pass line connecting the main steam line and the condenser without by way of a turbine, and the reactor is started-up by the extraction of control rods after the concentration of dissolved oxygen in the cooling water within a pressure vessel has been decreased below a predetermined value. Nuclear heating is started after the reactor water has been increased to about 150 0 C by pump heating after the end of the deaeration operation for preventing the concentration of hydrogen peroxide and oxygen in the reactor water from temporarily increasing immediately after the start-up. The corrosive atmosphere in the reactor vessel can thus be moderated. (Horiuchi, T.)

The 150 Credit-Hour Requirement and CPA Examination Pass Rates--A Four Year Study

Science.gov (United States)

Briggs, Gary P.; He, Lerong

2012-01-01

Debate concerning the minimum educational requirements of certified public accountant (CPA) candidates in the USA has been taking place for decades. This paper compares the sectional pass rates of CPA candidates from jurisdictions requiring 150 credit hours of college study with the pass rates of candidates from jurisdictions not requiring 150…

Fast neutron responses of CaF2:Tm Teflon TLD discs of different thicknesses

International Nuclear Information System (INIS)

Pradhan, A.S.; Hoffmann, W.

1986-01-01

The fact that in CaF 2 :Tm (TLD-300) the ratio of the heights of thermoluminescence (TL) glow peaks at 240 0 C and 150 0 C is greater for irradiations by high LET radiations than by gamma rays has been found useful for the simultaneous and separate measurement of fast neutron and gamma ray absorbed doses. A recent study has indicated that the mixed field dosimetric characteristics of CaF 2 :Tm could be significantly improved by using thin TLDs. In the present study, CaF 2 :Tm Teflon TLD discs of thickness as low as 0.05 mm were evaluated. The thin discs could be read out by using normal planchette heating if a 400 0 C heat treatment is given to the discs prior to irradiation and TL readout. Influence of encapsulation of thin dosemeters was studied and their utility in situations such as interface dosimetry is discussed. (author)

Operational and biological effects zones from base stations of cellular telephony

Energy Technology Data Exchange (ETDEWEB)

Geronikolou, St. A., E-mail: sgeronik@bioacademy.gr [Biomedical Research Foundation Academy of Athens, Athens (Greece); Zimeras, S., E-mail: zimste@aegean.gr [University of the Aegean, Karlovassi, Samos (Greece); Tsitomeneas, S. Th., E-mail: stsit@teipir.gr [Piraeus University of Applied Sciences, Aigaleo (Greece)

2016-03-25

The possible environmental impacts of cellular base stations are operational and biological. The operational effects comprise Εlectro-Μagnetic Interference (EMI), lightning alterations and aesthetic degradation. Both thermal and non-thermal biological effects depend on the absorption of UHF radiofrequencies used. We measured, calculated and estimated the impact zones. The results are: (a) The lightning lethal zone equal to the antenna height, (b) the EMI impact in a zone up to 40m and (c) the ICNIRP’s limits exceed to a zone of 8∼20m into the antenna’s radiation pattern (for 2G GSM and 3G UMTS station). Finally we conclude the adverse effects must not expected in a zone of more than 150m from the radiated antenna, whereas, there is possibility of stochastic effects in intermediate distances (20/40-150m).

LANL continuity of operations plan

Energy Technology Data Exchange (ETDEWEB)

Senutovitch, Diane M [Los Alamos National Laboratory

2010-12-22

The Los Alamos National Laboratory (LANL) is a premier national security research institution, delivering scientific and engineering solutions for the nation's most crucial and complex problems. Our primary responsibility is to ensure the safety, security, and reliability of the nation's nuclear stockpile. LANL emphasizes worker safety, effective operational safeguards and security, and environmental stewardship, outstanding science remains the foundation of work at the Laboratory. In addition to supporting the Laboratory's core national security mission, our work advances bioscience, chemistry, computer science, earth and environmental sciences, materials science, and physics disciplines. To accomplish LANL's mission, we must ensure that the Laboratory EFs continue to be performed during a continuity event, including localized acts of nature, accidents, technological or attack-related emergencies, and pandemic or epidemic events. The LANL Continuity of Operations (COOP) Plan documents the overall LANL COOP Program and provides the operational framework to implement continuity policies, requirements, and responsibilities at LANL, as required by DOE 0 150.1, Continuity Programs, May 2008. LANL must maintain its ability to perform the nation's PMEFs, which are: (1) maintain the safety and security of nuclear materials in the DOE Complex at fixed sites and in transit; (2) respond to a nuclear incident, both domestically and internationally, caused by terrorist activity, natural disaster, or accident, including mobilizing the resources to support these efforts; and (3) support the nation's energy infrastructure. This plan supports Continuity of Operations for Los Alamos National Laboratory (LANL). This plan issues LANL policy as directed by the DOE 0 150.1, Continuity Programs, and provides direction for the orderly continuation of LANL EFs for 30 days of closure or 60 days for a pandemic/epidemic event. Initiation of COOP operations may

F-doped SnO2 thin films grown on flexible substrates at low temperatures by pulsed laser deposition

International Nuclear Information System (INIS)

Kim, H.; Auyeung, R.C.Y.; Pique, A.

2011-01-01

Fluorine-doped tin oxide (SnO 2 :F) films were deposited on polyethersulfone plastic substrates by pulsed laser deposition. The electrical and optical properties of the SnO 2 :F films were investigated as a function of deposition conditions such as substrate temperature and oxygen partial pressure during deposition. High quality SnO 2 :F films were achieved under an optimum oxygen pressure range (7.4-8 Pa) at relatively low growth temperatures (25-150 deg. C). As-deposited films exhibited low electrical resistivities of 1-7 mΩ-cm, high optical transmittance of 80-90% in the visible range, and optical band-gap energies of 3.87-3.96 eV. Atomic force microscopy measurements revealed a reduced root mean square surface roughness of the SnO 2 :F films compared to that of the bare substrates indicating planarization of the underlying substrate.

The Operations Process

Science.gov (United States)

2010-03-26

important events receive the most attention. Ensures that absentees and flank units receive changes to the operation order. Transmits changes to them...York: Vintage Books, 1991. Fuller, J. F. C. Generalship: Its Diseases and Their Cure . Harrisburg, PA: Military Service Publishing Co., 1936

Dedekind σ-complete vector lattice of b-AM-compact operators ...

African Journals Online (AJOL)

We give several equivalent conditions characterizing the case when Krb-AM(E,F) is Dedekind σ-complete. Moreover, we describe the case when the space of all regular b-AM-compact operators from E to F is complete under the b-AM-norm. Keywords: Banach lattices, b-AM-compact operator, discrete space ...

Constraining N=1 supergravity inflation with non-minimal Kähler operators using δN formalism

International Nuclear Information System (INIS)

Choudhury, Sayantan

2014-01-01

In this paper I provide a general framework based on δN formalism to study the features of unavoidable higher dimensional non-renormalizable Kähler operators for N=1 supergravity (SUGRA) during primordial inflation from the combined constraint on non-Gaussianity, sound speed and CMB dipolar asymmetry as obtained from the recent Planck data. In particular I study the nonlinear evolution of cosmological perturbations on large scales which enables us to compute the curvature perturbation, ζ, without solving the exact perturbed field equations. Further I compute the non-Gaussian parameters f NL , τ NL and g NL for local type of non-Gaussianities and CMB dipolar asymmetry parameter, A CMB , using the δN formalism for a generic class of sub-Planckian models induced by the Hubble-induced corrections for a minimal supersymmetric D-flat direction where inflation occurs at the point of inflection within the visible sector. Hence by using multi parameter scan I constrain the non-minimal couplings appearing in non-renormalizable Kähler operators within, O(1), for the speed of sound, 0.02≤c s ≤1, and tensor to scalar, 10 −22 ≤r ⋆ ≤0.12. Finally applying all of these constraints I will fix the lower as well as the upper bound of the non-Gaussian parameters within, O(1−5)≤f NL ≤8.5, O(75−150)≤τ NL ≤2800 and O(17.4−34.7)≤g NL ≤648.2, and CMB dipolar asymmetry parameter within the range, 0.05≤A CMB ≤0.09

Constraining N=1 supergravity inflation with non-minimal Kähler operators using δN formalism

Energy Technology Data Exchange (ETDEWEB)

Choudhury, Sayantan [Physics and Applied Mathematics Unit, Indian Statistical Institute, 203 B.T. Road, Kolkata 700 108 (India)

2014-04-15

In this paper I provide a general framework based on δN formalism to study the features of unavoidable higher dimensional non-renormalizable Kähler operators for N=1 supergravity (SUGRA) during primordial inflation from the combined constraint on non-Gaussianity, sound speed and CMB dipolar asymmetry as obtained from the recent Planck data. In particular I study the nonlinear evolution of cosmological perturbations on large scales which enables us to compute the curvature perturbation, ζ, without solving the exact perturbed field equations. Further I compute the non-Gaussian parameters f{sub NL} , τ{sub NL} and g{sub NL} for local type of non-Gaussianities and CMB dipolar asymmetry parameter, A{sub CMB}, using the δN formalism for a generic class of sub-Planckian models induced by the Hubble-induced corrections for a minimal supersymmetric D-flat direction where inflation occurs at the point of inflection within the visible sector. Hence by using multi parameter scan I constrain the non-minimal couplings appearing in non-renormalizable Kähler operators within, O(1), for the speed of sound, 0.02≤c{sub s}≤1, and tensor to scalar, 10{sup −22}≤r{sub ⋆}≤0.12. Finally applying all of these constraints I will fix the lower as well as the upper bound of the non-Gaussian parameters within, O(1−5)≤f{sub NL}≤8.5, O(75−150)≤τ{sub NL}≤2800 and O(17.4−34.7)≤g{sub NL}≤648.2, and CMB dipolar asymmetry parameter within the range, 0.05≤A{sub CMB}≤0.09.

BDML Metadata: 150 [SSBD[Archive

Lifescience Database Archive (English)

Full Text Available Ce_KK_P002 BDML file for quantitative information about nuclear division dynamics o...f R08D7.1(RNAi) embryo quantitative information about nuclear division dynamics in R08D7.1(RNAi) embryo C. e

Análisis de flexibilidad y tasa de servicio de los proveedores de materias primas y artículos de acondicionamiento del departamento de logística de una fábrica L'Oréal

OpenAIRE

Oumakhlouf, Yasmina

2009-01-01

El Grupo L’Oreal es el Líder mundial de la industria cosmética. Está presente en más de 150 países y la cifra de su negocio consolidada en 2008 es de 14.300 millones de euros. En todo el mundo tiene más de 49.150 empleados. El grupo L’Oreal posee 44 fábricas, 39 de Productos Terminados (PT), y 5 de Materias Primas (MP), así como 18 centrales de distribución, nacionales e internacionales. Esas fábricas se ubican en las tres grandes zonas de actividad del grupo: Europa, Asia, y América del N...

12 CFR 5.34 - Operating subsidiaries.

Science.gov (United States)

2010-01-01

... services between financial institutions; (F) Providing management consulting, operational advice, and... rating (which rates risk management, operational controls, compliance, and asset quality) of 1 or 2 at..., the business of banking, as determined by the OCC, or otherwise under other statutory authority...

Siemens meelitab Eestisse 150 töökohta / Raigo Neudorf

Index Scriptorium Estoniae

Neudorf, Raigo

2002-01-01

Saksamaa elektroonikafirma Siemens tütarfirma Eestis võistleb selle eest, et tuua Eestisse emafirma 150 pakutavat töökohta majandustarkvara koostavatele spetsialistidele. Tabelid: Siemens Grupp Eesti tähtsamad majandusnäitajad. Siemensi kontsern

21 CFR 1271.150 - Current good tissue practice requirements.

Science.gov (United States)

2010-04-01

... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Current good tissue practice requirements. 1271... HUMAN CELLS, TISSUES, AND CELLULAR AND TISSUE-BASED PRODUCTS Current Good Tissue Practice § 1271.150 Current good tissue practice requirements. (a) General. This subpart D and subpart C of this part set...

47 CFR 90.355 - LMS operations below 512 MHz.

Science.gov (United States)

2010-10-01

... PRIVATE LAND MOBILE RADIO SERVICES Intelligent Transportation Systems Radio Service § 90.355 LMS... LMS station and the nearest co-channel base station of another licensee operating a voice system is 75... MHz, 150-170 MHz, and 450-512 MHz bands may use either base-mobile frequencies currently assigned the...

40 CFR 60.663 - Monitoring of emissions and operations.

Science.gov (United States)

2010-07-01

... 44 MW (150 million Btu/hr) heat input design capacity. (d) Monitor and record the periods of operation of the boiler or process heater if the design heat input capacity of the boiler or process heater... thermal conductivity, each equipped with a continuous recorder. (2) Where a condenser is the final...

Implications for Primordial Non-Gaussianity ($f_{NL}$) from weak lensing masses of high-z galaxy clusters

CERN Document Server

Jimenez, Raul

2009-01-01

The recent weak lensing measurement of the dark matter mass of the high-redshift galaxy cluster XMMUJ2235.3-2557 of (8.5 +- 1.7) x 10^{14} Msun at z=1.4, indicates that, if the cluster is assumed to be the result of the collapse of dark matter in a primordial gaussian field in the standard LCDM model, then its abundance should be 3-10 if the non-Gaussianity parameter f^local_NL is in the range 150-200. This value is comparable to the limit for f_NL obtained by current constraints from the CMB. We conclude that mass determination of high-redshift, massive clusters can offer a complementary probe of primordial non-gaussianity.

14 CFR Appendix F to Part 135 - Airplane Flight Recorder Specification

Science.gov (United States)

2010-01-01

... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Airplane Flight Recorder Specification F.... F Appendix F to Part 135—Airplane Flight Recorder Specification The recorded values must meet the....125 0.004g 6. Pitch Attitude ±75% ±2° 1 or 0.25 for airplanes operated under § 135.152(j) 0.5° A...

Milestones in 150 years of the chemical industry

International Nuclear Information System (INIS)

Morris, P.J.T.; Campbell, W.A.; Roberts, H.L.

1991-01-01

Milestones in 150 years of the Chemical Industry charts the history of the industry in its crucial role of meetings basic human needs. The book provides on overview of developments in the industry in the fields of health, clothing, energy, materials and information technology and sets the information in an historical context. It will be of interest to chemists in industry, academic, business and to the lay public. (author)

D ampersand D Characterization of the 232-F Old Tritium Facility at the Savannah River Site

International Nuclear Information System (INIS)

Scallon, K.L.; England, J.L.

1995-01-01

The 232-F ''Old Tritium Facility'' operated in the 1950s as the first tritium production facility at the Savannah River Site (SRS). In 1957, the 232-F operation ceased with tritium production turned over to a larger, technologically improved facility at SRS. The 232-F Facility was abandoned in 1958 and the process areas have remained contaminated with radiological, hazardous and mixed constituents. Decontamination and decommissioning (D ampersand D) of the 232-F Facility is scheduled to occur in the years 1995-1996. This paper presents the D ampersand D characterization efforts for the 232-F Facility

13 CFR 120.150 - What are SBA's lending criteria?

Science.gov (United States)

2010-01-01

... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false What are SBA's lending criteria... Policies Applying to All Business Loans Credit Criteria for Sba Loans § 120.150 What are SBA's lending... depth of management; (c) Strength of the business; (d) Past earnings, projected cash flow, and future...

Reduction of hydrogen desorption temperature of ball-milled MgH2 by NbF5 addition

International Nuclear Information System (INIS)

Recham, N.; Bhat, V.V.; Kandavel, M.; Aymard, L.; Tarascon, J.-M.; Rougier, A.

2008-01-01

Enhanced sorption properties of ball-milled MgH 2 are reported by adding NbF 5 . Among various catalyst amounts, 2 mol% of NbF 5 reveals to be the optimum concentration leading to significant reduction of the desorption temperature as well as faster kinetics of ball-milled MgH 2 . At 200 deg. C, temperature at which MgH 2 does not show any activity, MgH 2NbF 5 /2mol% composite desorbs 3.2 wt.% of H 2 in 50 mins. Interestingly, the addition of NbF 5 is also associated with an increase in the desorption pressure. At 300 deg. C, MgH 2NbF 5 /2mol% composite starts to desorb hydrogen at 600 mbar in comparison with 1 mbar for MgH 2 . Further improvements were successfully achieved by pre-grinding NbF 5 prior to ball-milling the catalyst with MgH 2 . Such pre-ground NbF 5 catalyzed MgH 2 composite desorbs 3 wt.% of H 2 at 150 deg. C. Improved properties are associated with smaller activation energies down to values close to the enthalpy of formation of MgH 2 . Finally, the mechanism at the origin of the enhancement is discussed in terms of catalyst stability, MgF 2 formation and electronic density localization

History of 232-F, tritium extraction processing

International Nuclear Information System (INIS)

Blackburn, G.W.

1994-08-01

In 1950 the Atomic Energy Commission authorized the Savannah River Project principally for the production of tritium and plutonium-239 for use in thermonuclear weapons. 232-F was built as an interim facility in 1953--1954, at a cost of $3.9M. Tritium extraction operations began in October, 1955, after the reactor and separations startups. In July, 1957 a larger tritium facility began operation in 232-H. In 1958 the capacity of 232-H was doubled. Also, in 1957 a new task was assigned to Savannah River, the loading of tritium into reservoirs that would be actual components of thermonuclear weapons. This report describes the history of 232-F, the process for tritium extraction, and the lessons learned over the years that were eventually incorporated into the new Replacement Tritium Facility

Advances on Polymer Optical Fiber Gratings Using a KrF Pulsed Laser System Operating at 248 nm

Directory of Open Access Journals (Sweden)

Carlos A. F. Marques

2018-03-01

Full Text Available This paper presents the achievements and progress made on the polymer optical fiber (POF gratings inscription in different types of Fiber Bragg Gratings (FBGs and long period gratings (LPGs. Since the first demonstration of POFBGs in 1999, significant progress has been made where the inscription times that were higher than 1 h have been reduced to 15 ns with the application of the krypton fluoride (KrF pulsed laser operating at 248 nm and thermal treatments such as the pre-annealing of fibers. In addition, the application of dopants such as benzyl dimethyl ketal (BDK has provided a significant decrease of the fiber inscription time. Furthermore, such improvements lead to the possibility of inscribing POF gratings in 850 nm and 600 nm, instead of only the 1550 nm region. The progress on the inscription of different types of polymer optical fiber Bragg gratings (POFBGs such as chirped POFBGs and phase-shifted POFBGs are also reported in this review.

CERTAIN PROPERTIES OF AN OPERATOR INVOLVING SUBORDINATION

Directory of Open Access Journals (Sweden)

Ajai P. Terwase

2015-12-01

Full Text Available The concept of subordination can be traced back to LindelÄof since 1909, but other mathematicians like Littlewood (1925 and Rogosinski (1939 introduced the term and developed the basic theories. Subordination now plays an important role in complex analysis. The idea of univalent subordination can be stated as follows: Let f and g be analytic in E. Then f is said to be subordinate to g, if g is univalent in E, f(0 = g(0 and every element of f(E is also an element of g(E. We denote the subordination by f≺ g. Here, we apply a lemma of Miller and Mocanu to obtain a series of best possible subordination theorems. We also make use of an operator studied by Cho and Srivastava, and by Cho and Kim in this particular work. Thus, in this research work, we consider properties of an operator aforementioned involving subordinations with new results briefly highlighted.

Two years of experience with the [ 18F]FDG production module

Science.gov (United States)

Kim, Sang Wook; Hur, Min Goo; Chai, Jong-Seo; Park, Jeong Hoon; Yu, Kook Hyun; Jeong, Cheol Ki; Lee, Goung Jin; Min, Young Don; Yang, Seung Dae

2007-08-01

Chemistry module for a conventional [18F]FDG production by using tetrabutylammonium bicarbonate (TBA) and an acidic hydrolysis has been manufactured and evaluated. In this experiment, 75 mM (pH 7.5-7.8) of TBA solution and a ca. 2-curies order of [18F]-fluoride have been used for the evaluation. The commercial acidic purification cartridge was purchased from GE or UKE. The operation system (OS) was programmed with Lab-View which was selected because of its easy customization of the OS. Small sized solenoid valves (Burkert; type 6124) were selected to reduce the module dimensions (W 350 × D 270 × H 250). The total time for the synthesis of [18F]FDG was 30 ± 3 min. The production yield of [18F]FDG was 60 ± 2% on an average at EOS, with the decay uncorrected. This experimental data show that the traditional chemistry module can provide a good [18F]FDG production yield by optimizing the operational conditions. The radiochemical purity, radionuclidic purity, acidity, residual solvent, osmolality and endotoxin were determined to assess the quality of [18F]FDG. The examined contents for the quality control of [18F]FDG were found to be suitable for a clinical application.

Correlations of Behavioral Deficits with Brain Pathology Assessed through Longitudinal MRI and Histopathology in the HdhQ150/Q150 Mouse Model of Huntington's Disease.

Directory of Open Access Journals (Sweden)

Ivan Rattray

Full Text Available A variety of mouse models have been developed that express mutant huntingtin (mHTT leading to aggregates and inclusions that model the molecular pathology observed in Huntington's disease. Here we show that although homozygous HdhQ150 knock-in mice developed motor impairments (rotarod, locomotor activity, grip strength by 36 weeks of age, cognitive dysfunction (swimming T maze, fear conditioning, odor discrimination, social interaction was not evident by 94 weeks. Concomitant to behavioral assessments, T2-weighted MRI volume measurements indicated a slower striatal growth with a significant difference between wild type (WT and HdhQ150 mice being present even at 15 weeks. Indeed, MRI indicated significant volumetric changes prior to the emergence of the "clinical horizon" of motor impairments at 36 weeks of age. A striatal decrease of 27% was observed over 94 weeks with cortex (12% and hippocampus (21% also indicating significant atrophy. A hypothesis-free analysis using tensor-based morphometry highlighted further regions undergoing atrophy by contrasting brain growth and regional neurodegeneration. Histology revealed the widespread presence of mHTT aggregates and cellular inclusions. However, there was little evidence of correlations between these outcome measures, potentially indicating that other factors are important in the causal cascade linking the molecular pathology to the emergence of behavioral impairments. In conclusion, the HdhQ150 mouse model replicates many aspects of the human condition, including an extended pre-manifest period prior to the emergence of motor impairments.

Los Alamos KrF laser program

International Nuclear Information System (INIS)

Jensen, R.J.; Cartwright, D.C.

1985-01-01

Los Alamos is currently developing the krypton fluoride (KrF) laser - a highly efficient laser able to emit very intense bursts of short-wavelength photons - as a research tool for the general study of high-density matter, as well as for use in laser fusion. The KrF laser operates at 1/4 μm, close to the short-wavelength limit for conventional optical material, but still in the region where standard optical techniques can be used. The excited-state lifetime of the KrF lasing medium is short - as a result of both spontaneous emission and deactivation from collisions - making it impossible to store energy within the lasing medium for times significant to electrical pumping. However, an optical multiplexing scheme is being developed that will generate short, intense pulses of 1/4-μm light by overcoming the short storage time of the laser and taking advantage of the high gain of the KrF medium

Licensing of nuclear reactor operators

International Nuclear Information System (INIS)

1979-09-01

Recommendations are presented for the licensing of nuclear reactor operators in units licensed according to the legislation in effect. They apply to all physical persons designated by the Operating Organization of the nuclear reactor or reactors to execute any of the following functional activities: a) to manipulate the controls of a definite reactor b) to direct the authorized activities of the reactor operators licesed according to the present recommendations. (F.E.) [pt

150 Bulgarian students visit CERN

CERN Multimedia

Alizée Dauvergne

2010-01-01

Between 27 March and 8 April 2010, 150 Bulgarian students from the Astronomical Observatory in Varna visited CERN as part of the “From Galileo to CERN” programme. Bulgarian students participating in the "From Galileo to CERN" educational programme. “It’s interesting to combine astronomy and particle physics”, explains Svejina Dimitrova, organiser of the programme and Director of Varna Astronomical Observatory. The three groups, each one comprising 50 students, first visited Pisa, Padua and other places in Italy  related to Galileo’s life. “Thanks to the visit, students understood telescopes and why Galileo is such an important scientist”, says Svejina. After Italy, they came to CERN for three days and visited several sites: Linac, the Computer Centre CCC, etc. Another group of Bulgarian students in their visit to CERN. “They became aware that particle physics is not only the...

Adsorption gas chromatography with 150-ms {sup 216}Po

Energy Technology Data Exchange (ETDEWEB)

Vogt, A [Bern Univ. (Switzerland); Gaeggeler, H W; Tuerler, A [Paul Scherrer Inst. (PSI), Villigen (Switzerland)

1997-09-01

A gas chromatography apparatus was developed, which allows experiments with volatile radionuclides having shorter half-lives than one second. This apparatus was tested with the 150-ms isotope {sup 216}Po. Experimental data were compared with a Monte Carlo model to determine the adsorption enthalpy {Delta}H{sub a}. (author) 2 figs., 2 refs.

20 CFR 655.150 - Interstate clearance of job order.

Science.gov (United States)

2010-04-01

... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Interstate clearance of job order. 655.150... job order. (a) SWA posts in interstate clearance system. The SWA must promptly place the job order in... transmit a copy of its active job order to all States listed in the job order as anticipated worksites...

On building superpotentials in F-GUTs

International Nuclear Information System (INIS)

Saidi, E. H.

2016-01-01

Using characters of finite group representations, we construct the fusion algebras of operators of the spectrum of F-theory grand unified theories (GUTs). These fusion relations are used in building monodromy-invariant superpotentials of the low-energy effective 4D N=1 supersymmetric GUT models

Gyroaveraging operations using adaptive matrix operators

Science.gov (United States)

Dominski, Julien; Ku, Seung-Hoe; Chang, Choong-Seock

2018-05-01

A new adaptive scheme to be used in particle-in-cell codes for carrying out gyroaveraging operations with matrices is presented. This new scheme uses an intermediate velocity grid whose resolution is adapted to the local thermal Larmor radius. The charge density is computed by projecting marker weights in a field-line following manner while preserving the adiabatic magnetic moment μ. These choices permit to improve the accuracy of the gyroaveraging operations performed with matrices even when strong spatial variation of temperature and magnetic field is present. Accuracy of the scheme in different geometries from simple 2D slab geometry to realistic 3D toroidal equilibrium has been studied. A successful implementation in the gyrokinetic code XGC is presented in the delta-f limit.

19 CFR 12.150 - Merchandise prohibited by economic sanctions; detention; seizure or other disposition; blocked...

Science.gov (United States)

2010-04-01

...; detention; seizure or other disposition; blocked property. 12.150 Section 12.150 Customs Duties U.S. CUSTOMS...; detention; seizure or other disposition; blocked property. (a) Generally. Merchandise from certain countries... the United States shall be detained until the question of its release, seizure, or other disposition...

Ion conductivities of ZrF4-BaF2-CsF glasses

International Nuclear Information System (INIS)

Kawamoto, Yoji; Nohara, Ichiro

1987-01-01

The glass-forming region in the ZrF 4 -BaF 2 -CsF glass system has been determined and the ac conductivity and the transport number of fluoride ions have been measured. The conductivities of compounds β-Cs 2 ZrF 6 , α-SrZrF 6 , α-BaZrF 6 , β-BaZrF 6 and α-PbZrF 6 have also been measured. These results and a previous study of ZrF 4 -BaF 2 -MF n (M: the groups I-IV metals) glasses revealed the following: (1) the ZrF 4 -BaF 2 -CsF glasses are exclusively fluoride-ion conductors; (2) the ionic conductivities of ZrF 4 -based glasses are predominantly determined by the activation energies for conduction; (3) the activation energy for conduction decreases with an increase in the average polarizability of glass-constituting cations; (4) a decrease in average Zr-F bond length and a lowering of the average F coordination number of Zr are presumed to increase the activation energy for conduction. Principles of developing ZrF 4 -based glasses with higher conductivities have also been proposed. (Auth.)

The Perforation-Operation time Interval; An Important Mortality Indicator in Peptic Ulcer Perforation.

Science.gov (United States)

Surapaneni, Sushama; S, Rajkumar; Reddy A, Vijaya Bhaskar

2013-05-01

To find out the significance of the Perforation-Operation Interval (POI) with respect to an early prognosis, in patients with peritonitis which is caused by peptic ulcer perforation. Case series. Place and Duration of the Study: Department of General Surgery, Konaseema Institute of Medical Sciences and RF Amalapuram, Andhra Pradesh, India from 2008-2011. This study included 150 patients with generalized peritonitis, who were diagnosed to have Perforated Peptic Ulcers (PPUs). The diagnosis of the PPUs was established on the basis of the history , the clinical examination and the radiological findings. The perforation-operation interval was calculated from the time of onset of the symptoms like severe abdominal pain or vomiting till the time the patient was operated. Out of the 150 patients 134 were males and 16 were females, with a male : female ratio of 9:1. Their ages ranged between 25-70 years. Out of the 150 patients, 65 patients (43.3%) presented within 24 hours of the onset of severe abdominal pain (Group A), 27 patients (18%) presented between 24-48 hours of the onset of severe abdominal pain (Group B) and 58 patients (38.6%) presented after 48 hours. There was no mortality in Group A and the morbidity was more in Group B and Group C. There were 15 deaths in Group C. The problem of peptic ulcer perforation with its complication, can be decreased by decreasing the perforation -operation time interval, which as per our study, appeared to be the single most important mortality and morbidity indicator in peptic ulcer perforation.

Development of advanced Czochralski Growth Process to produce low cost 150 KG silicon ingots from a single crucible for technology readiness

Science.gov (United States)

1981-01-01

The goals in this program for advanced czochralski growth process to produce low cost 150 kg silicon ingots from a single crucible for technology readiness are outlined. To provide a modified CG2000 crystal power capable of pulling a minimum of five crystals, each of approximately 30 kg in weight, 150 mm diameter from a single crucible with periodic melt replenishment. Crystals to have: resistivity of 1 to 3 ohm cm, p-type; dislocation density below 1- to the 6th power per cm; orientation (100); after growth yield of greater than 90%. Growth throughput of greater than 2.5 kg per hour of machine operation using a radiation shield. Prototype equipment suitable for use as a production facility. The overall cost goal is $.70 per peak watt by 1986. To accomplish these goals, the modified CG2000 grower and development program includes: (1) increased automation with a microprocessor based control system; (2) sensors development which will increase the capability of the automatic controls system, and provide technology transfer of the developed systems.

Recent experiments at Brookhaven: level structure of N = 86 isotones 156Yb and 150Gd

International Nuclear Information System (INIS)

Sunyar, A.W.

1980-01-01

States of the N = 86 isotones 156 Yb and 150 Gd have been studied by means of the 144 Sm( 16 O,4n) 156 Yb, 113 In( 46 Ti,p2n) 156 Yb, and 124 Sn( 30 Si,4n) 150 Gd reactions. Levels have been established to spin 36 h-bar and over 12.5 MeV in excitation in 150 Gd and to beyond spin 25 h-bar in 156 Yb. The systematics of levels in the N = 86 isotones from 150 Gd to 156 Yb are described, and the near-spherical shell model description for states in this region to near spin 30 h-bar is discussed. A T/sub 1/2/ = 6 ns, 72-keV isomeric transition in 156 Yb has been discovered, and an E1 multipolarity is assigned to this transition. The spin-parity of the isomeric state is established as 11 - . 6 figures

Thermal evolution of low-temperature manganese centers in X-irradiated CaF2:Mn

International Nuclear Information System (INIS)

Jahan, M.S.; Cooke, D.W.

1984-01-01

Thermal evolution of the radiation-induced defects in CaF 2 :Mn (0.1% by weight) are investigated by ESR techniques. The Mn + resonance is found to decay at 200 K with an activation energy of 0.44 eV and frequency factor 2.8 x 10 8 s -1 which agree with previous luminescence and optical absorption measurements. This activation energy and decay temperature also agree with that of the previously described H center. It is concluded that the luminescence in CaF 2 :Mn results from thermal release of holes at H centers with ultimate recombination at Mn + ions producing excited state Mn 2+ (*). Relaxation yields the observed 500 nm emission characteristic of Mn 2+ . A second defect which decays at 150 K is observed but not identified. (author)

Tank 18-F And 19-F Tank Fill Grout Scale Up Test Summary

International Nuclear Information System (INIS)

Stefanko, D.; Langton, C.

2012-01-01

High-level waste (HLW) tanks 18-F and 19-F have been isolated from FTF facilities. To complete operational closure the tanks will be filled with grout for the purpose of: (1) physically stabilizing the tanks, (2) limiting/eliminating vertical pathways to residual waste, (3) entombing waste removal equipment, (4) discouraging future intrusion, and (5) providing an alkaline, chemical reducing environment within the closure boundary to control speciation and solubility of select radionuclides. This report documents the results of a four cubic yard bulk fill scale up test on the grout formulation recommended for filling Tanks 18-F and 19-F. Details of the scale up test are provided in a Test Plan. The work was authorized under a Technical Task Request (TTR), HLE-TTR-2011-008, and was performed according to Task Technical and Quality Assurance Plan (TTQAP), SRNL-RP-2011-00587. The bulk fill scale up test described in this report was intended to demonstrate proportioning, mixing, and transportation, of material produced in a full scale ready mix concrete batch plant. In addition, the material produced for the scale up test was characterized with respect to fresh properties, thermal properties, and compressive strength as a function of curing time.

TANK 18-F AND 19-F TANK FILL GROUT SCALE UP TEST SUMMARY

Energy Technology Data Exchange (ETDEWEB)

Stefanko, D.; Langton, C.

2012-01-03

High-level waste (HLW) tanks 18-F and 19-F have been isolated from FTF facilities. To complete operational closure the tanks will be filled with grout for the purpose of: (1) physically stabilizing the tanks, (2) limiting/eliminating vertical pathways to residual waste, (3) entombing waste removal equipment, (4) discouraging future intrusion, and (5) providing an alkaline, chemical reducing environment within the closure boundary to control speciation and solubility of select radionuclides. This report documents the results of a four cubic yard bulk fill scale up test on the grout formulation recommended for filling Tanks 18-F and 19-F. Details of the scale up test are provided in a Test Plan. The work was authorized under a Technical Task Request (TTR), HLE-TTR-2011-008, and was performed according to Task Technical and Quality Assurance Plan (TTQAP), SRNL-RP-2011-00587. The bulk fill scale up test described in this report was intended to demonstrate proportioning, mixing, and transportation, of material produced in a full scale ready mix concrete batch plant. In addition, the material produced for the scale up test was characterized with respect to fresh properties, thermal properties, and compressive strength as a function of curing time.

13.-20. VI võtab ehtekunstnike rühmitus F.F.F.F....

Index Scriptorium Estoniae

2004-01-01

Rühmitus F.F.F.F. (Ketli Tiitsar, Kristi Paap, Kaire Rannik, Berit Teeäär, Maria Valdma) võtab osa Bostonis toimuvast rahvusvahelisest ehtekunstinäitusest ja konverentsist "ContacT 2004", juhendab Massachusetts College of Art üliõpilastele ja kunstnikele korraldatud workshop'i "SWOP". Bakalar Gallerys esineb rühmitus näitusega "Igapäevaleib", osalejate individuaalset loomingut eksponeerib galerii Mobilia

33 CFR 117.791 - Hudson River.

Science.gov (United States)

2010-07-01

... least 24 hours notice is given. (d) The draw of the state highway bridge, mile 150.2 between Troy and... between Troy and Green Island, operates as follows: (1) From April 1 through December 15, the draw shall... opened. (f) The draws of the 112th Street bridge, mile 155.4 between Troy and Cohoes operate as follows...

Spectral classification of medium-scale high-latitude F region plasma density irregularities

International Nuclear Information System (INIS)

Singh, M.; Rodriguez, P.; Szuszczewicz, E.P.; Sachs Freeman Associates, Bowie, MD)

1985-01-01

The high-latitude ionosphere represents a highly structured plasma. Rodriguez and Szuszczewicz (1984) reported a wide range of plasma density irregularities (150 km to 75 m) at high latitudes near 200 km. They have shown that the small-scale irregularities (7.5 km to 75 m) populated the dayside oval more often than the other phenomenological regions. It was suggested that in the lower F region the chemical recombination is fast enough to remove small-scale irregularities before convection can transport them large distances, leaving structured particle precipitation as the dominant source term for irregularities. The present paper provides the results of spectral analyses of pulsed plasma probe data collected in situ aboard the STP/S3-4 satellite during the period March-September 1978. A quantitative description of irregularity spectra in the high-latitude lower F region plasma density is given. 22 references

150 Years of Italian CO2 Emissions and Economic Growth

DEFF Research Database (Denmark)

Annicchiarico, Barbara; Bennato, Anna Rita; Chini, Emilio Zanetti

This paper examines the relationship between economic growth and carbon dioxide emissions in Italy considering the developments in a 150-year time span. Using several statistical techniques, we find that GDP growth and carbon dioxide emissions are strongly interrelated, with a dramatic change...

Mixed Estimates for Degenerate Multilinear Operators Associated to Simplexes

OpenAIRE

Kesler, Robert

2013-01-01

We prove that the degenerate trilinear operator $C_3^{-1,1,1}$ given by the formula \\begin{eqnarray*} C_3^{-1,1,1}(f_1, f_2, f_3)(x)=\\int_{x_1 < x_2 < x_3} \\hat{f_1}(x_1) \\hat{f_2}(x_2) \\hat{f_3}(x_3) e^{2\\pi i x (-x_1 + x_2 + x_3)} dx_1dx_2 dx_3 \\end{eqnarray*} satisfies the new estimates \\begin{eqnarray*} ||C_3^{-1,1,1}(f_1, f_2, f_3)||_{\\frac{1}{\\frac{1}{p_1}+\\frac{1}{p_2}+\\frac{1}{p_3}}} \\lesssim_{p_1, p_2, p_3} ||\\hat{f}_1||_{p^\\prime_1} ||f_2||_{p_2}||f_3||_{p_3} \\end{eqnarray*} for all...

On the convergence of nonlinear Beltrami type operators

Directory of Open Access Journals (Sweden)

Riccardo De Arcangelis

1986-11-01

Full Text Available One of the results proved is the following: if (fh is a sequence of K-quasiregular mappings, converging to f  in L1loc , whose jacobians verify a weak integrability condition, then the solutions of Dirichlet problems for the nonlinear Laplace-Beltrami operator associated to each fh converge to the solution of the Dirichlet problem for the nonlinear Laplace-Beltrami operator associated to f. Such result is deduced as a particular case of a more general theorem concerning nonlinear operators. The case of K-quasiconformal functions fh is also treated. A class of weighted Sobolev spaces associated to quasiconformal mappings is studied.

Validation of an HPLC method for determination of chemical purity of [18F]fluoromisonidazole ([18F]FMISO)

International Nuclear Information System (INIS)

Nascimento, Natalia C.E.S.; Oliveira, Mércia L.; Lima, Fernando R.A.; Silveira, Marina B.; Ferreira, Soraya Z.; Silva, Juliana B.

2017-01-01

[ 18 F]Fluoromisonidazole ([ 18 F]FMISO) is a nitroimidazole derivative labelled with fluorine-18 that selectively binds to hypoxic cells. It has been shown to be a suitable PET tracer for imaging hypoxia in tumors as well as in noncancerous tissues. [ 18 F]FMISO was prepared using a TRACERlabMX FDG ® module (GE) with cassettes, software sequence and reagents kits from ABX. In this work, we aimed to develop and to validate a new high performance liquid chromatography (HPLC) method for determination of chemical purity of [ 18 F]FMISO. Analyses were performed with an Agilent chromatograph equipped with radioactivity and UV detectors. [ 18 F]FMISO and impurities were separated on a C18 column by gradient elution with water and acetonitrile. Selectivity, linearity, detection limit (DL), quantification limit (LQ), precision, accuracy and robustness were assessed to demonstrate that the HPLC method is adequate for its intended purpose. The HPLC method showed a good precision, as all RSD values were lower than 5%. Robustness was evaluated considering a variation on parameters such mobile phase gradient and flow rate. Results evidenced that the HPLC method is validated and is suitable for radiochemical purity evaluation of [ 18 F]FMISO, considering operational conditions of our laboratory. As an extension of this work, other analytical methods used for [ 18 F]FMISO quality control should be evaluated, in compliance with good manufacture practice. (author)

PC data station for Hitachi F-2000 spectrofluorimeter

International Nuclear Information System (INIS)

Yakub Ali, Mohd; Dhoble, A.R.; Jadhav, R.T.; Godbole, S.V.

2004-01-01

The paper describes the PC based data station for stand-alone HIT ACHI F-2000 Spectrofluorimeter, for data acquisition, storage and analysis. The hardware link between the instrument and PC is made through RS232 serial port. The state of art software for control and data management is designed, developed and implemented in Visual Basic (Version 6). The software features on-screen editing of all operation parameters of the instrument and the operational control is achieved by Visual Basic command words communicated through serial port. Using this system, in addition to acquiring and storage of spectral data, it was possible to obtain the normalized absorption spectra of the samples. PC adapted Hitachi F-2000 Spectrofluorimeter can be successfully used for various operations such as photometric detection of UO22+ ions, recording of emission and excitation spectra and time evolution of fluorescence intensity on continuous UV irradiation. The data storage achieved through PC adaptation has also enabled recording of absorption spectra. (author)

Comparison of coronary artery calcium screening image quality between C-150 and e-Speed electron beam scanners.

Science.gov (United States)

Budoff, Matthew J; Shinbane, Jerold S; Oudiz, Ronald J; Child, Janis; Carson, Sivi; Chau, Alex; Tseng, Philip; Gao, Yanlin; Mao, Songshou

2005-03-01

The newest generation of electron beam tomographic scanner (e-Speed) has increased spatial and temporal resolution compared with the C-150 XP scanner. The aim of this study was to evaluate coronary artery calcium screening image quality between the e-Speed and C-150 scanners (GE Imatron, San Francisco, CA). Studies from 41 patients (14 women and 27 men) who underwent serial coronary artery calcium screening with the C-150 (first study) and the e-Speed (second study) were analyzed. Individual computed tomography (CT) slices were assessed for coronary artery motion artifacts, and CT Hounsfield units (HU) and noise values (CT HU standard deviation) at 16 discrete cardiac sites were measured and averaged. With the e-Speed scanner, there were significant decreases in right coronary artery motion artifacts compared with the C-150 scanner (0.3% versus 1.8%, P Image quality is significantly improved with use of the e-Speed scanner, due to its improved temporal and spatial resolution, compared with the C-150 scanner.

46 CFR Table II to Part 150 - Grouping of Cargoes

Science.gov (United States)

2010-10-01

... solution Potassium oleate Potassium salt of polyolefin acid Propyl acetate Propylene carbonate Propylene... lignosulfonate solution Sodium polyacrylate solution 2 Sodium salt of Ferric hydroxyethylethylenediamine... 46 Shipping 5 2010-10-01 2010-10-01 false Grouping of Cargoes II Table II to Part 150 Shipping...

Anisotropic p-f mixing mechanism explaining anomalous magnetic properties in Ce monopnictides

International Nuclear Information System (INIS)

Takahashi, H.; Kasuya, T.

1985-01-01

The indirect f-f-interaction derived from fourth-order perturbation theory with respect to the p-f mixing is calculated using the valence bands obtained by the APW band calculations. The type of the f-f-interactions is described as the coupling through the symmetry exchange under the cubic crystal field, which cannot be written as a simple bilinear type of 4f spin operator. It is necessary to consider the short-range-ordering effect as well as the non-linear effect of the p-f mixing to explain the fact that a type-I antiferromagnetic ordering is established by the second-order transition in CeBi. (author)

33 CFR 150.518 - What are the inspection requirements for work vests and immersion suits?

Science.gov (United States)

2010-07-01

... requirements for work vests and immersion suits? 150.518 Section 150.518 Navigation and Navigable Waters COAST... vests and immersion suits? (a) All work vests and immersion suits must be inspected by the owner or... a work vest or immersion suit is inspected and is in serviceable condition, then it may remain in...

TFTR initial operations

International Nuclear Information System (INIS)

Young, K.M.; Bell, M.; Blanchard, W.R.

1984-01-01

TFTR (Tokamak Fusion Test Reactor) has operated since December 1982 with ohmically heated plasmas. Routine operation with feedback control of plasma current, position and density has been obtained for plasmas with Isub(p) approx.= 800 kA, a = 68 cm, R = 250 cm, and Bsub(t) = 27 kG. A maximum plasma current of 1 MA was achieved with q approx.= 2.5. Energy confinement times of approx. 150 msec were measured for hydrogen and deuterium plasmas with n-barsub(e) approx.= 2 x 10 13 cm -3 , Tsub(e)(O) approx.= 1.5 keV, Tsub(i)(O) approx.= 1.5 keV and Zsub(eff) approx.= 3. The preliminary results suggest a size-cubed scaling from PLT, and are consistent with Alcator C scaling where tau approx. nR 2 a. Initial measurements of plasma disruption characteristics indicate current decay rates of approx. 800 kA in 8 ms which is within the TFTR design requirement of 3 MA in 3 ms. (author)

7 CFR 929.150 - Transfer or assignment of sales history.

Science.gov (United States)

2010-01-01

... 7 Agriculture 8 2010-01-01 2010-01-01 false Transfer or assignment of sales history. 929.150... MARKETING SERVICE (Marketing Agreements and Orders; Fruits, Vegetables, Nuts), DEPARTMENT OF AGRICULTURE... Transfer or assignment of sales history. (a) If indebtedness is incurred with regard to the acreage to...

‘Praise beyond Words’: Psalm 150 as grand finale of the crescendo in the Psalter

Directory of Open Access Journals (Sweden)

Dirk J. Human

2011-04-01

Full Text Available Without doubt the final hymn of the Psalter can be described as the climax, or grand finale, of the Israelite faith’s most known hymnbook. In this psalm, sound and action are blended into a picture of ecstatic joy. The whole universe is called upon to magnify Yah(weh, the God of Israel. The text poses various exegetical challenges. In the past, Psalm 150 was traditionally analysed as a single text; but with the advent of the canonical and redactionhistorical approaches to the interpretation of the Book of Psalms, Psalm 150 can be interpreted as part of the final Hallel (Pss 146–150, or Book V (Pss 107–150 of the Psalter. This view opens up new possibilities for reading the psalm in broader contexts and its broader literary context(s illuminate its theological significance. This article is an attempt at reflecting on the psalm’s context(s, structure, Gattung and dates of origin, tradition-historical relations to the Pentateuch, Psalms and other Old Testament texts. Ultimately some reflections on the psalm’s theological significance will be suggested.

Fluorine uptake into the human tooth from a thin layer of F-releasing material

International Nuclear Information System (INIS)

Yamamoto, H.; Nomachi, M.; Yasuda, K.; Iwami, Y.; Ebisu, S.; Komatsu, H.; Sakai, T.; Kamiya, T.

2007-01-01

Using the proton induced gamma-ray emission (PIGE) method (TIARA, Japan), we have studied fluorine (F) distribution in the human tooth under various conditions. Here, we report F uptake into the human tooth from a thin layer of F-releasing low viscous resin (FLVR). Crowns of human teeth were horizontally cut and the dentin of the cut surface was first covered with four kinds of FLVR (FL-Bond, Reactmer Bond, Xeno Bond, and Protect Liner F; thickness, 50-150 μm) according to the manufacturers' instructions. Non-F-releasing and F-releasing filling resins were also hardened, on the cut surfaces of crowns covered with four kinds of FLVR thin layers. The type of the non-F-releasing filling materials used was LITE FIL IIP: G1-A (FL-Bond and LITE FIL IIP), G2-A (Reactmer Bond and LITE FIL IIP), G3-A (Xeno Bond and LITE FIL IIP), and G4-A (Protect Liner F and LITE FIL IIP). The types of F-releasing filling materials used were G1-B (FL-Bond and Beautifil), G2-B (Reactmer Bond and Reactmer Paste), G3-B (Xeno Bond and Xeno CF Paste), and G4-B (Protect Liner F and Teethmate F-1). Treatment and measurements of specimens were the same as previously reported [H. Yamamoto, M. Nomahci, K. Yasuda, Y. Iwami, S. Ebisu, N. Yamamoto, T. Sakai, T. Kamiya, Nucl. Instr. and Meth. B 210 (2003) 388]. F uptake from specimens following one month of application was estimated from 2-D maps. F penetration was observed in all teeth of G1-A-G4-A groups. The maximum values of F concentration in each tooth and F penetration depth were larger for larger F concentrations in FLVR. FLVR was useful for the F uptake into the tooth, and the F distribution near the thin layer of FLVR depended on the materials used. Between G1-A and G1-B or G4-A and G4-B, the F uptake was significantly different. We were able to obtain fundamental data, which were useful for the analysis of F transportation relating to prevention of caries

Fluorine uptake into the human tooth from a thin layer of F-releasing material

Energy Technology Data Exchange (ETDEWEB)

Yamamoto, H. [Department of Restorative Dentistry and Endodontology, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita, Osaka, 565-0871 (Japan)]. E-mail: yhiroko@dent.osaka-u.ac.jp; Nomachi, M. [Graduate School of Science, Osaka University, Toyonaka, Osaka, 560-0043 (Japan); Yasuda, K. [Wakasa Wan Energy Research Center, Tsuruga, Fukui, 914-0192 (Japan); Iwami, Y. [Department of Restorative Dentistry and Endodontology, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Ebisu, S. [Department of Restorative Dentistry and Endodontology, Graduate School of Dentistry, Osaka University, 1-8 Yamadaoka, Suita, Osaka, 565-0871 (Japan); Komatsu, H. [Graduate School of Dental Medicine, Hokkaido University, Sapporo, Hokkaido, 060-8585 (Japan); Sakai, T. [Advanced Radiation Technology Center, JAERI, Takasaki, Gunma, 370-1292 (Japan); Kamiya, T. [Advanced Radiation Technology Center, JAERI, Takasaki, Gunma, 370-1292 (Japan)

2007-07-15

Using the proton induced gamma-ray emission (PIGE) method (TIARA, Japan), we have studied fluorine (F) distribution in the human tooth under various conditions. Here, we report F uptake into the human tooth from a thin layer of F-releasing low viscous resin (FLVR). Crowns of human teeth were horizontally cut and the dentin of the cut surface was first covered with four kinds of FLVR (FL-Bond, Reactmer Bond, Xeno Bond, and Protect Liner F; thickness, 50-150 {mu}m) according to the manufacturers' instructions. Non-F-releasing and F-releasing filling resins were also hardened, on the cut surfaces of crowns covered with four kinds of FLVR thin layers. The type of the non-F-releasing filling materials used was LITE FIL IIP: G1-A (FL-Bond and LITE FIL IIP), G2-A (Reactmer Bond and LITE FIL IIP), G3-A (Xeno Bond and LITE FIL IIP), and G4-A (Protect Liner F and LITE FIL IIP). The types of F-releasing filling materials used were G1-B (FL-Bond and Beautifil), G2-B (Reactmer Bond and Reactmer Paste), G3-B (Xeno Bond and Xeno CF Paste), and G4-B (Protect Liner F and Teethmate F-1). Treatment and measurements of specimens were the same as previously reported [H. Yamamoto, M. Nomahci, K. Yasuda, Y. Iwami, S. Ebisu, N. Yamamoto, T. Sakai, T. Kamiya, Nucl. Instr. and Meth. B 210 (2003) 388]. F uptake from specimens following one month of application was estimated from 2-D maps. F penetration was observed in all teeth of G1-A-G4-A groups. The maximum values of F concentration in each tooth and F penetration depth were larger for larger F concentrations in FLVR. FLVR was useful for the F uptake into the tooth, and the F distribution near the thin layer of FLVR depended on the materials used. Between G1-A and G1-B or G4-A and G4-B, the F uptake was significantly different. We were able to obtain fundamental data, which were useful for the analysis of F transportation relating to prevention of caries.

Myofilament Calcium Sensitivity: Mechanistic Insight into TnI Ser-23/24 and Ser-150 Phosphorylation Integration

Directory of Open Access Journals (Sweden)

Hussam E Salhi

2016-12-01

Full Text Available Troponin I (TnI is a major regulator of cardiac muscle contraction and relaxation. During physiological and pathological stress, TnI is differentially phosphorylated at multiple residues through different signaling pathways to match cardiac function to demand. The combination of these TnI phosphorylations can exhibit an expected or unexpected functional integration, whereby the function of two phosphorylations are different than that predicted from the combined function of each individual phosphorylation alone. We have shown that TnI Ser-23/24 and Ser-150 phosphorylation exhibit functional integration and are simultaneously increased in response to cardiac stress. In the current study, we investigated the functional integration of TnI Ser-23/24 and Ser-150 to alter cardiac contraction. We hypothesized that Ser-23/24 and Ser-150 phosphorylation each utilize distinct molecular mechanisms to alter the TnI binding affinity within the thin filament. Mathematical modeling predicts that Ser-23/24 and Ser-150 phosphorylation affect different TnI affinities within the thin filament to distinctly alter the Ca2+-binding properties of troponin. Protein binding experiments validate this assertion by demonstrating pseudo-phosphorylated Ser-150 decreases the affinity of isolated TnI for actin, whereas Ser-23/24 pseudo-phosphorylation is not different from unphosphorylated. Thus, our data supports that TnI Ser-23/24 affects TnI-TnC binding, while Ser-150 phosphorylation alters TnI-actin binding. By measuring force development in troponin-exchanged skinned myocytes, we demonstrate that the Ca2+ sensitivity of force is directly related to the amount of phosphate present on TnI. Furthermore, we demonstrate that Ser-150 pseudo-phosphorylation blunts Ser-23/24-mediated decreased Ca2+-sensitive force development whether on the same or different TnI molecule. Therefore, TnI phosphorylations can integrate across troponins along the myofilament. These data demonstrate

The OsO(3)F(+) and mu-F(OsO(3)F)(2)(+) cations: their syntheses and study by Raman and (19)F NMR spectroscopy and electron structure calculations and X-ray crystal structures of [OsO(3)F][PnF(6)] (Pn = As, Sb), [OsO(3)F][HF](2)[AsF(6)], [OsO(3)F][HF][SbF(6)], and [OsO(3)F][Sb(3)F(16)].

Science.gov (United States)

Gerken, Michael; Dixon, David A; Schrobilgen, Gary J

2002-01-28

The fluoride ion donor properties of OsO(3)F(2) have been investigated. The salts [OsO(3)F][AsF(6)], [OsO(3)F][HF](2)[AsF(6)], mu-F(OsO(3)F)(2)[AsF(6)], [OsO(3)F][HF](2)[SbF(6)], and [OsO(3)F][HF][SbF(6)] have been prepared by reaction of OsO(3)F(2) with AsF(5) and SbF(5) in HF solvent and have been characterized in the solid state by Raman spectroscopy. The single-crystal X-ray diffraction studies of [OsO(3)F][AsF(6)] (P2(1)/n, a = 7.0001(11) A, c = 8.8629(13) A, beta = 92.270(7) degrees, Z = 4, and R(1) = 0.0401 at -126 degrees C), [OsO(3)F][SbF(6)] (P2(1)/c, a = 5.4772(14) A, b = 10.115(3) A, c = 12.234(3) A, beta = 99.321(5) degrees, Z = 4, and R(1) = 0.0325 at -173 degrees C), [OsO(3)F][HF](2)[AsF(6)] (P2(1)/n, a = 5.1491(9) A, b = 8.129(2) A, c = 19.636(7) A, beta = 95.099(7) degrees, Z = 4, and R(1) = 0.0348 at -117 degrees C), and [OsO(3)F][HF][SbF(6)] (Pc, a = 5.244(4) A, b = 9.646(6) A, c = 15.269(10) A, beta = 97.154(13) degrees, Z = 4, and R(1) = 0.0558 at -133 degrees C) have shown that the OsO(3)F(+) cations exhibit strong contacts to the anions and HF solvent molecules giving rise to cyclic, dimeric structures in which the osmium atoms have coordination numbers of 6. The reaction of OsO(3)F(2) with neat SbF(5) yielded [OsO(3)F][Sb(3)F(16)], which has been characterized by (19)F NMR spectroscopy in SbF(5) and SO(2)ClF solvents and by Raman spectroscopy and single-crystal X-ray diffraction in the solid state (P4(1)m, a = 10.076(6) A, c = 7.585(8) A, Z = 2, and R(1) = 0.0858 at -113 degrees C). The weak fluoride ion basicity of the Sb(3)F(16)(-) anion resulted in an OsO(3)F(+) cation (C(3)(v) point symmetry) that is well isolated from the anion and in which the osmium is four-coordinate. The geometrical parameters and vibrational frequencies of OsO(3)F(+), ReO(3)F, mu-F(OsO(3)F)(2)(+), (FO(3)Os--FPnF(5))(2), and (FO(3)Os--(HF)(2)--FPnF(5))(2) (Pn = As, Sb) have been calculated using density functional theory methods.

Linear representation of algebras with non-associative operations which are satisfy in the balanced functional equations

International Nuclear Information System (INIS)

Ehsani, Amir

2015-01-01

Algebras with a pair of non-associative binary operations (f, g) which are satisfy in the balanced quadratic functional equations with four object variables considered. First, we obtain a linear representation for the operations, of this kind of binary algebras (A,f,g), over an abelian group (A, +) and then we generalize the linear representation of operations, to an algebra (A,F) with non-associative binary operations which are satisfy in the balanced quadratic functional equations with four object variables. (paper)

Increasing the flexibility of base-load generating units in operation on fossil fuel

Energy Technology Data Exchange (ETDEWEB)

Girshfel' d, V Ya; Khanaev, V A; Volkova, E D; Gorelov, V A; Gershenkroi, M L

1979-01-01

Increasing the flexibility of base-load generating units operating on fossil fuel by modifying them is a necessary measure. The highest economic effect is attained with modification of gas- and oil-fired generating units in the Western United Power Systems of the European part of the SPSS. On the basis of available experience, 150- and 200-MW units can be extensively used to regulate the power in the European part of the SPSS through putting them into reserve for the hours of the load dip at night. The change under favorable conditions of 150- and 200-MW units operating on coal to a district-heating operating mode does not reduce the possibilities for flexible operation of these units because it is possible greatly to unload the turbines while the minimum load level of the pulverized fuel fired boiler is retained through transferring a part of the heat load to the desuperheater. It is necessary to accumulate and analyze experience with operation of generating units (especially of supercritical units) with regular shutdowns and starts of groups of units and to solve the problems of modification of generating units, with differentiation with respect to types of fuel and to the united power supply system.

Hybrid Ti:Sapphire / KrF laser facility GARPUN for combined subpicosecond/nanosecond laser-matter interaction studies

International Nuclear Information System (INIS)

Zvorykin, V.D.; Ionin, A.A.; Konyashcenko, A.V.; Levchenko, A.O.; Krokhin, O.N.; Mesyats, G.A.; Molchanov, A.G.; Rorulev, M.A.

2006-01-01

Complete test of publication follows. Hybrid laser facility consisting of Ti:Sapphire front end, 3ω converter, and e-beam-pumped large-aperture KrF amplifiers is under construction to generate combined sub-picosecond/nanosecond pulses in UV spectral range at 248-nm wavelength. This is a part of the Petawatt excimer laser project started at P.N. Lebedev Physical Institute. In comparison with commonly used solid-state chirped-pulse amplifiers (CPA), KrF amplifiers have following advantages: (i) low-density gaseous matter with three orders of magnitude lower non-linear refraction index has a small value of B-integral and negligible pulse distortion; (ii) short radiation lifetime τ r = 6 ns of the upper laser level of KrF(B-X) transition (with accounting for collisions τ c ∼ 2 ns), that means the population inversion is recovered each 2 ns during the pumping time, which is typically τ p ≥ 100 ns for technical reasons. Thus, it might be possible eliminating of very costly large-aperture compressor gratings and to amplify both short τ sh c and long τ long ≥ τ c pulses in the same amplifiers, as a short pulse does not affect the gain during the most of pumping. This gives a unique opportunity for realization of fast-ignition scheme in Inertial Confinement Fusion using large-scale KrF drivers. The Ti:Sapphire front end 'Start 248M' currently operates with the following parameters: rep rate 10 Hz, pulse energy and duration at fundamental wavelength (744 nm) > 8 mJ and 0.5 mJ and 0.4 mJ, 740 nm) and multi-pass amplifier (10 Hz, > 15 mJ, 740 nm), both pumped by 2ω pulsed Lotis LS-2134 Nd:YAG laser (10 Hz, 10 ns, 532 nm) with distributed energies of 5 and 70 mJ, two-gratings compressor, and 3ω converter with two BBO crystals and total efficiency 8%. EMG 150MSC Lambda Physik KrF laser is used afterwards to generate ns pulses and to amplify fs pulses in its two separate discharge chambers. Two e-beam pumped KrF amplifiers Berdysh and GARPUN with active volumes 10

77 FR 38375 - Advisory Circular (AC) 150/5345-53D, Airport Lighting Equipment Certification Program; Proposed...

Science.gov (United States)

2012-06-27

... DEPARTMENT OF TRANSPORTATION Federal Aviation Administration Advisory Circular (AC) 150/5345-53D... Advisory Circular (AC) 150/5345-53D, Airport Lighting Equipment Certification Program, is being circulated... on a separate document and not embedded in the draft AC. Additionally, please provide justification...

Design of the free-air ionization chamber, FAC-IR-150, for X-ray dosimetry

Science.gov (United States)

Mohammadi, Seyed Mostafa; Tavakoli-Anbaran, Hossein

2018-03-01

The primary standard for X-ray dosimetry is based on the free-air ionization chamber (FAC). Therefore, the Atomic Energy Organization of Iran (AEOI) designed the free-air ionization chamber, FAC-IR-150, for low and medium energy X-ray dosimetry. The purpose of this work is the study of the free-air ionization chamber characteristics and the design of the FAC-IR-150. The FAC-IR-150 dosimeter has two parallel plates, a high voltage plate and a collector plate. A guard electrode surrounds the collector and is separated by an air gap. A group of guard strips is used between up and down electrodes to produce a uniform electric field in all the ion chamber volume. This design involves introducing the correction factors and determining the exact dimensions of the ionization chamber by using Monte Carlo simulation.

The safety approach in the operation of EDF power plants

International Nuclear Information System (INIS)

Bertron, L.; Mira, J.J.

1988-01-01

To get a view on what is involved in maintaining a high level of safety in the operation of EdF nuclear power plants, it may be recalled that in 1987, 76 % of the EdF production was nuclear. The nuclear plants include thirty-four standard PWR 900 plants, fourteen PWR 1300 plants, the 305 MW SENA PWR, the four 500 MW GCR: CHINON A3 plant, St-LAURENT A1 (390 MW), A2 (450 MW) and BUGEY 1 (540 MW), the 233 MW PHENIX fast breeder reactor and the CREYS-MALVILLE 1200 MW fast breeder reactor, now being prepared for a new startup after the 1987 incident. So the importance of a safe operation of this investment is considerable for EdF, which is the designer, owner, industrial architect and operator. According to the French regulations, EdF is responsible for the safe operation of its power plants. A considerable human component is also at stake, as the safe operation of plants implies all the personnel to varying degrees. There are 15,000 such employees, all of whom have to be trained, competent and motivated. The operation of this system for 340 reactor-years has to-date resulted in no incident of any significant impact on the environment. Right from the start, safety in operation has always been an essential and clearly stated priority. Among other lessons the Three-Mile Island and Chernobyl accidents have reinforced the conviction that the human factors, the man-machine interface, and the safety culture were determining elements. With forty-eigh PWR plants in service, the problem is to maintain safe operation of a system now running at cruising speed, but also including some units (particularly the GCRs) that must be prepared for decommissioning. In addition EDF has to demonstrate the safe operations of CREYS MALVILLE, fast breeder reactor

Oxidation of UO2 at 150 to 3500C

International Nuclear Information System (INIS)

White, G.D.; Knox, C.A.; Gilbert, E.R.; Johnson, A.B. Jr.

1983-07-01

Oxidation of UO 2 through breached LWR spent fuel rods during interim storage in air atmospheres is a potential mechanism for degradation of cladding integrity. The temperature-time range of published data are inadequate to establish long term behavior under dry storage conditions. Consequently, tests are being conducted in the temperature range of 150 to 350 0 C on unirradiated pellets to evaluate fuel oxidation behavior. The tests have revealed significant-to-minor oxidation at temperatures down to 200 0 C and no measurable oxidation at 150 0 C for times up to 3000 hours. Oxidation at 200 0 C for 2000 hours led to formation of low density particulate U 3 O 8 which destroys pellet integrity. Oxidation of UO 2 pellets at 215 and 250 0 C was signifcantly accelerated by the presence of 1 volume percent NO 2 in the air. NO 2 is a potential constituent of the air, forming by radiolysis in the gamma radiation field associated with spent fuel assemblies. NO 2 reaction with UO 2 pellets leads to accelerated formation of UO 3 and pellet disintegration. 11 references, 15 figures

A novel decomposition technique of friable asbestos by CHClF2-decomposed acidic gas

International Nuclear Information System (INIS)

Yanagisawa, Kazumichi; Kozawa, Takahiro; Onda, Ayumu; Kanazawa, Masazumi; Shinohara, Junichi; Takanami, Tetsuro; Shiraishi, Masatsugu

2009-01-01

Asbestos was widely used in numerous materials and building products due to their desirable properties. It is, however, well known that asbestos inhalation causes health damage and its inexpensive decomposition technique is necessary to be developed for pollution prevention. We report here an innovative decomposition technique of friable asbestos by acidic gas (HF and HCl) generated from the decomposition of CHClF 2 by the reaction with superheated steam at 800 deg. C. Chrysotile-asbestos fibers were completely decomposed to sellaite and magnesium silicofluoride hexahydrate by the reaction with CHClF 2 -decomposed acidic gas at 150 deg. C for 30 min. At high temperatures beyond 400 deg. C, sellaite and hematite were detected in the decomposed product. In addition, crocidolite containing wastes and amosite containing wastes were decomposed at 500 deg. C and 600 deg. C for 30 min, respectively, by CHClF 2 -decomposed acidic gas. The observation of the reaction products by phase-contrast microscopy (PCM) and scanning electron microscopy (SEM) confirmed that the resulting products did not contain any asbestos

Operational reliability of high pressure steam lines of pearlitic steels after 150-200 thousand h service

International Nuclear Information System (INIS)

Veksler, E.Ya.; Chajkovskij, V.M.; Osasyuk, V.V.

1980-01-01

Usage of both calculational and physical methods is recommended to estimate a service operating life of long-term working steam line materials. Application of these methods is demonstrated when studying steam line bends made of 12MKh and 12Kh1MF pearlitic steels. Good coincidence of results for the determination of residual durability of steam lines is obtained using these two methods [ru

Evaluation of E.M.F. exposure from medical electrical equipment

Energy Technology Data Exchange (ETDEWEB)

Aniolczyk, H.; Mamrot, P.; Politanski, P. [Nofer Institute of Occupational Medicine, Lodz (Poland)

2006-07-01

he medical electric and electronic equipment, including electro surgical devices, short- and microwave diathermy units, and magnetic resonance imaging (MRI) systems, belong to the most hazardous sources of electromagnetic emissions. The electromagnetic emissions can interfere with emissions from other medical equipment located in the same facility (e.g. operation rooms) thus having impact on their work, but more importantly, they can be dangerous to patients, medical personnel operating them and other persons. In the present project, an assessment of E.M.F. intensity was performed for more than 2 000 electro surgical devices (330 khz, 440 khz and 1.76 MHz frequency ranges), 1 200 diathermy units and 45 MRI 0.2 - 1.5 T systems. E.M.F. exposure of medical staff was assessed based on respective national hygienic standards. The actual exposure levels were found to exceed the admissible values in Poland. The recorded E.M.F. intensities were compared with relevant Who and U E recommendations (e.g. I.C.N.I.R.P. guidelines, 1998, Directive 2004/40/E.C.). The findings revealed that for 18% of the devices examined, the E.M.F. was higher than the E.M.F. intensity values recommended by U E. (authors)

Evaluation of E.M.F. exposure from medical electrical equipment

International Nuclear Information System (INIS)

Aniolczyk, H.; Mamrot, P.; Politanski, P.

2006-01-01

he medical electric and electronic equipment, including electro surgical devices, short- and microwave diathermy units, and magnetic resonance imaging (MRI) systems, belong to the most hazardous sources of electromagnetic emissions. The electromagnetic emissions can interfere with emissions from other medical equipment located in the same facility (e.g. operation rooms) thus having impact on their work, but more importantly, they can be dangerous to patients, medical personnel operating them and other persons. In the present project, an assessment of E.M.F. intensity was performed for more than 2 000 electro surgical devices (330 khz, 440 khz and 1.76 MHz frequency ranges), 1 200 diathermy units and 45 MRI 0.2 - 1.5 T systems. E.M.F. exposure of medical staff was assessed based on respective national hygienic standards. The actual exposure levels were found to exceed the admissible values in Poland. The recorded E.M.F. intensities were compared with relevant Who and U E recommendations (e.g. I.C.N.I.R.P. guidelines, 1998, Directive 2004/40/E.C.). The findings revealed that for 18% of the devices examined, the E.M.F. was higher than the E.M.F. intensity values recommended by U E. (authors)

Renormalizations and operator expansion in sigma model

International Nuclear Information System (INIS)

Terentyev, M.V.

1988-01-01

The operator expansion (OPE) is studied for the Green function at x 2 → 0 (n(x) is the dynamical field ofσ-model) in the framework of the two-dimensional σ-model with the O(N) symmetry group at large N. As a preliminary step we formulate the renormalization scheme which permits introduction of an arbitrary intermediate scale μ 2 in the framework of 1/N expansion and discuss factorization (separation) of small (p μ) momentum region. It is shown that definition of composite local operators and coefficient functions figuring in OPE is unambiguous only in the leading order in 1/N expansion when dominant are the solutions with extremum of action. Corrections of order f(μ 2 )/N (here f(μ 2 ) is the effective interaction constant at the point μ 2 ) in composite operators and coefficient functions essentially depend on factorization method of high and low momentum regions. It is shown also that contributions to the power corrections of order m 2 x 2 f(μ 2 )/N in the Green function (here m is the dynamical mass-scale factor in σ-model) arise simultaneously from two sources: from the mean vacuum value of the composite operator n ∂ 2 n and from the hard particle contributions in the coefficient function of unite operator. Due to the analogy between σ-model and QCD the obtained result indicates theoretical limitations to the sum rule method in QCD. (author)

Research helps EdF improve operating practices and control rooms [at nuclear power plants in France

International Nuclear Information System (INIS)

Leckner, J.-M.

1989-01-01

In September 1982, EdF set up a team to analyse incidents occurring in nuclear plants in France and elsewhere. This team consists of two groups of analysts: one for studying technical factors and one for investigating human factors. Medium-term objectives for the team involve work on the principal causes of malfunction and the extent to which significant incidents recur. Experience feedback, training and multifactor events, are the group's prime concerns. Information is gathered from two sources: simulators provide an analysis of operator behaviour in incident and accident situations; and plants themselves provide in-service data. The malfunctions which are examined are significant incidents listed according to ten criteria, the main ones being scrams, safety injection, events relating to technical specifications, malicious acts, discharge of radioactive substances and exposure of staff to ionizing radiation. Every week, all incidents are examined and communicated to the relevant analysts. The analyst must then draw up a summary, to include: a description of the facts; an analysis of the causes; and ideas for preventive actions. Many of the recommendations have now been carried out, with the result that recent years have seen a decline in human errors at French plants. (author)

Thermal analysis and phase diagrams of the LiF BiF{sub 3} e NaF BiF{sub 3} systems; Analise termica e diagramas de fase dos sistemas LiF-BiF{sub 3} e NaF-BiF{sub 3}

Energy Technology Data Exchange (ETDEWEB)

Nakamura, Gerson Hiroshi de Godoy

2013-07-01

Investigations of the binary systems LiF-BiF{sub 3} and NaF-BiF{sub 3} were performed with the objective of clarifying the thermal behavior and phase equilibria of these systems and their intermediary phases, an important requisite for high-quality crystal growth. Several samples in the entire range of compositions (0 to 100 mol% BiF{sub 3}) of both systems were subjected to experiments of differential thermal analysis (DTA) and thermogravimetry (TG), and also of differential scanning calorimetry (DSC). A few specific compositions were selected for X-ray diffraction to supplement the experimental data. Due to the high vulnerability of BiF{sub 3} to oxygen contamination, its volatility and propensity to destroy metal parts upon heating, it was necessary to determine the optimal conditions for thermal analysis before investigating the systems themselves. Phase relations in the system LiF-BiF{sub 3} were completely clarified and a phase diagram was calculated and evaluated via the commercial software Factsage. The diagram itself consists in a simple peritectic system in which the only intermediary compound, LiBiF{sub 4}, decomposes into LiF and a liquid phase. The NaF-BiF{sub 3} system could not be completely elucidated and the phase relations in the NaF poor side (> 50% BiF{sub 3}) are still unknown. In the NaF rich side, however, the possible peritectoid decomposition of the compound NaBiF{sub 4} was identified. In both systems X-ray diffraction yielded crystal structures discrepant with the literature for the intermediary phases, LiBiF{sub 4}, NaBiF{sub 4} and a solid solution of NaF and BiF{sub 3} called {sup I.} The observed structures remain unknown and explanations for the discrepancies were proposed. (author)

PROJECTIZING AN OPERATING NUCLEAR FACILITY

International Nuclear Information System (INIS)

Adams, N

2007-01-01

This paper will discuss the evolution of an operations-based organization to a project-based organization to facilitate successful deactivation of a major nuclear facility. It will describe the plan used for scope definition, staff reorganization, method estimation, baseline schedule development, project management training, and results of this transformation. It is a story of leadership and teamwork, pride and success. Workers at the Savannah River Site's (SRS) F Canyon Complex (FCC) started with a challenge--take all the hazardous byproducts from nearly 50 years of operations in a major, first-of-its-kind nuclear complex and safely get rid of them, leaving the facility cold, dark, dry and ready for whatever end state is ultimately determined by the United States Department of Energy (DOE). And do it in four years, with a constantly changing workforce and steadily declining funding. The goal was to reduce the overall operating staff by 93% and budget by 94%. The facilities, F Canyon and its adjoined sister, FB Line, are located at SRS, a 310-square-mile nuclear reservation near Aiken, S.C., owned by DOE and managed by Washington Group International subsidiary Washington Savannah River Company (WSRC). These facilities were supported by more than 50 surrounding buildings, whose purpose was to provide support services during operations. The radiological, chemical and industrial hazards inventory in the old buildings was significant. The historical mission at F Canyon was to extract plutonium-239 and uranium-238 from irradiated spent nuclear fuel through chemical processing. FB Line's mission included conversion of plutonium solutions into metal, characterization, stabilization and packaging, and storage of both metal and oxide forms. The plutonium metal was sent to another DOE site for use in weapons. Deactivation in F Canyon began when chemical separations activities were completed in 2002, and a cross-functional project team concept was implemented to successfully

Quasi-continuous wave and continuous wave laser operation of Eu:KGd(WO4)2 crystal on a 5D0 → 7F4 transition

International Nuclear Information System (INIS)

Dashkevich, V I; Orlovich, V A; Bui, A A; Bagayev, S N; Vatnik, S M; Loiko, P A; Yumashev, K V; Kuleshov, N V; Pavlyuk, A A

2015-01-01

We report on the first demonstration of quasi-continuous wave (quasi-CW) and real CW room-temperature lasing on the 5 D 0  →  7 F 4 transition of Eu 3+ -doped material using a 25 at.%Eu 3+  : KGd(WO 4 ) 2 crystal pumped into the 7 F 1  →  5 D 1 transition by a diode-end-pumped Nd 3+  : KGd(WO 4 ) 2 /KTP green laser at 533.6 nm. The maximum CW output power of this laser at 702.3 nm is 5.3 mW with 1.4% green-to-red conversion efficiency. In quasi-CW operation mode with a 10% duty cycle, the peak power of ms long pulses reaches ∼54 mW, which corresponds to the optical conversion efficiency of 3.5%. (letter)

Effect of gamma irradiation in the pupal stage on the fall armyworm parent and F1 generations reproduction

International Nuclear Information System (INIS)

Arthur, V.; Wiendl, F.M.; Duarte-Aguilar, J.A.; Wiendl, J.A.

1994-01-01

To induce sterilization into F 1 generation, pupae of the fall armyworm Spodoptera frugiperda (Smith, 1797) (Lepidoptera, Noctuidae) were irradiated at the age of five days. The radiation source was a Cobalt-60 panoramic irradiator. The pupae were irradiated at the dose-rate of 2.60 kGy/h with doses of 0 (control), 50, 75, 100 and 125 Gy. The hatching of the eggs laid by the adults originated from the irradiated pupae with dose of 125 Gy were 15.0 and 10.0 percent for males and females respectively. Crossing this irradiated parent generation, it could be found that the F 1 generation reached 93.0 percent of hatching for both sexes

Desenvolvimento de porta-enxertos de umbuzeiro em resposta à adubação com nitrogênio e fósforo ‘Umbuzeiro’ rootstocks development as a answer for fertilization with nitrogen and phosphorous

Directory of Open Access Journals (Sweden)

Alberto Soares de Melo

2005-04-01

Full Text Available A adubação, notadamente com nitrogênio e fósforo, é fundamental no estádio de desenvolvimento inicial de mudas de frutíferas. Porém, existem poucas informações científicas com respeito do umbuzeiro. Assim, objetivou-se avaliar o efeito de doses de nitrogênio e fósforo no desenvolvimento de porta-enxertos de umbuzeiro (Spondias tuberosa Arr. Câm.. O experimento foi conduzido sob telado, na Universidade Federal de Sergipe, em um delineamento em blocos ao acaso, em esquema fatorial 4 x 4, sendo quatro níveis de nitrogênio e quatro de fósforo (0, 50, 100 e 150kg ha-1 de N e P2O5, respectivamente na forma de uréia e superfosfato simples, em quatro repetições. O maior ganho em altura (12,52cm foi obtido com as doses de 97,58kg ha-1 de N, enquanto o maior incremento no diâmetro do colo (2,18mm foi obtido com as doses de 150kg ha-1 de N e 150kg ha-1 de P2O5. O maior número de folhas foi observado na presença de 126,03kg ha-1 de N e 150kg ha-1 de P2O5. A maior produção de massa seca da parte aérea total foi constatada na dose de 98,71kg ha-1 de N e 150kg ha-1 de P2O5. A área foliar cresceu linearmente para ambos fatores As adubações estudadas contribuem de forma positiva para a formação de mudas de umbuzeiro, podendo antecipar a formação de porta-enxertos para algumas fruteiras do gênero Spondias. Doses de fósforo a partir de 150kg ha-1 não são recomendadas quando se pretende produzir picles, a partir do xilopódio do umbuzeiro.The fertilization, notable with nitrogen and phosphorous, is fundamental on initial development stadium on fruits nursery trees. However, there is little scientific information about ‘umbuzeiro’. This work had as objective to evaluate the effect of nitrogen and phosphorous’ doses on ‘umbuzeiro’ rootstocks (Spondias tuberosa Arr. Câm.. The experiment was carried out under nursery at ‘Universidade Federal de Sergipe’ being used experimental design of randomized blocks in factorial

Luminescent emission of LiF: Mg, Ti exposed to UV radiation; Emision luminiscente del LiF: Mg, Ti expuesto a la radiacion UV

Energy Technology Data Exchange (ETDEWEB)

Estrada G, A. [Estudiante de Facultad de Ciencias, UNAM, Circuito Exterior, 04500 Mexico D.F. (Mexico); Castano M, V.M. [Centro de Fisica Aplicada y Tecnologia Avanzada, UNAM, Campus Juriquilla, Queretaro (Mexico); Cruz Z, E.; Garcia F, F. [Instituto de Ciencias Nucleares UNAM, A.P. 70-543 Mexico D.F. (Mexico)

2002-07-01

It was investigated the luminescent emission stimulated by heat (Tl) of LiF: Mg, Ti crystals which were exposed to UV radiation coming from a mercury lamp. Since this crystal depends on the thermal history, it has been used a thermal treatment consisting of a baking at 380 C during one hour for each reading and they were irradiated with UV. The brilliance curves between 5 and 840 minutes of exposure in the face of UV light were obtained. An important loss in the response, starting from 150 minutes of irradiation was observed. Also the relative intensity of the brilliance curve decay when the crystals being stored in darkness and room temperature conditions, which is according to the results in the literature about. (Author)

Ethylenediammonium fluorotrioxophosphate at 150 K

Czech Academy of Sciences Publication Activity Database

Fábry, Jan; Dušek, Michal; Krupková, Radmila; Vaněk, Přemysl

E62, - (2006), o3217-o3219 ISSN 1600-5368 R&D Projects: GA ČR GA202/05/0421 Grant - others:UK(CZ) 158/2004/B-CH/PrF Institutional research plan: CEZ:AV0Z10100520 Keywords : x-ray structure determination * hydrogen bonds * conformation of ethylenediammonium Subject RIV: BM - Solid Matter Physics ; Magnetism Impact factor: 0.567, year: 2006

Hypersensitive transition spectrum of f-element and coordination structure

International Nuclear Information System (INIS)

Cao Xuan; Song Chongli; Zhu Youngjun

1992-10-01

Some f-f transitions of Ln(An) metallic ions have particular super-sensitivity to the change of coordination environments. This is called super-sensitive transitions. Based on the irreducible tensor operator method, a computation model and corresponding computer program for calculating the hypersensitive transition spectrum of f-element were developed. By comparing the theoretical spectra of all possible coordination structures with experimental one, the possible coordination structures of complex can be determined. The coordination structures of Nd 3+ , Er 3 + hydrate and their extraction complex with H(DEHP) were successfully determined by this method, and the experimental spectra were also assigned

De la mutualisation à la coopération. : Élaboration d’un référentiel de connaissances en santé au travail.

OpenAIRE

Masse , Max; Madec , Laurent

2015-01-01

International audience; Dans le cadre de la rationalisation de l’appareil de formation initiale de ses 150 écoles de service public, le Ministère de la fonction publique française a mobilisé des professionnels issus de ces écoles pour engager des travaux de mutualisation pédagogique à travers la conception de référentiels de compétences-formation. Nous montrerons que cette mutualisation n’a permis de ne constituer que des référentiels de connaissances potentiellement actionnables (Penalva) po...

Thermal analysis and phase diagrams of the LiF BiF3 e NaF BiF3 systems

International Nuclear Information System (INIS)

Nakamura, Gerson Hiroshi de Godoy

2013-01-01

Investigations of the binary systems LiF-BiF 3 and NaF-BiF 3 were performed with the objective of clarifying the thermal behavior and phase equilibria of these systems and their intermediary phases, an important requisite for high-quality crystal growth. Several samples in the entire range of compositions (0 to 100 mol% BiF 3 ) of both systems were subjected to experiments of differential thermal analysis (DTA) and thermogravimetry (TG), and also of differential scanning calorimetry (DSC). A few specific compositions were selected for X-ray diffraction to supplement the experimental data. Due to the high vulnerability of BiF 3 to oxygen contamination, its volatility and propensity to destroy metal parts upon heating, it was necessary to determine the optimal conditions for thermal analysis before investigating the systems themselves. Phase relations in the system LiF-BiF 3 were completely clarified and a phase diagram was calculated and evaluated via the commercial software Factsage. The diagram itself consists in a simple peritectic system in which the only intermediary compound, LiBiF 4 , decomposes into LiF and a liquid phase. The NaF-BiF 3 system could not be completely elucidated and the phase relations in the NaF poor side (> 50% BiF 3 ) are still unknown. In the NaF rich side, however, the possible peritectoid decomposition of the compound NaBiF 4 was identified. In both systems X-ray diffraction yielded crystal structures discrepant with the literature for the intermediary phases, LiBiF 4 , NaBiF 4 and a solid solution of NaF and BiF 3 called I. The observed structures remain unknown and explanations for the discrepancies were proposed. (author)

LHCb: F.E.C. for DAQ networks

CERN Multimedia

Floros, G; Neufeld, N

2014-01-01

The demand for faster and more reliable networks is growing day by day both in commercial and scientific applications, driving many innovations in network protocols, fiber optics and network-controllers. Operating fast links on relatively inexpensive hardware is a very important challenging aspect of this. One important way to enable this is to provide the network with an existing mechanism of error correction, called Forward Error Correction (F.E.C.). Although error-correcting codes exist for over six decades and F.E.C. is applied in various projects, it is still not widespread in Ethernet networks. F.E.C. introduces a very cost effective way to expand the limits of any network based on micro-controllers synthesized on FPGAs, but it is provided only for specific applications, such as backplane systems. Most of the FPGA and/or IP core vendors either do not provide this feature on their Ethernet implementations or their F.E.C. implementations are based on Ethernet micro-controllers that have a different struct...

77 FR 16928 - Drawbridge Operation Regulation; Miami River, Miami, FL

Science.gov (United States)

2012-03-23

...,'' and then click on the balloon shape in the ``Actions'' column. If you submit your comments [[Page... N.W. 12th Avenue Bridge provides a vertical clearance of 22 feet above mean high water in the closed position, and a horizontal clearance of 150 feet. The normal operating schedule for the bridge is set forth...

41 CFR 102-192.150 - What are your general responsibilities as a program level mail manager?

Science.gov (United States)

2010-07-01

... responsibilities as a program level mail manager? 102-192.150 Section 102-192.150 Public Contracts and Property... general responsibilities as a program level mail manager? Your responsibilities at the program level include— (a) Working closely with the agency mail manager and mail center managers who handle significant...

Innovative Telemonitoring System for Cardiology: From Science to Routine Operation

Science.gov (United States)

Kastner, P.; Morak, J.; Modre, R.; Kollmann, A.; Ebner, C.; Fruhwald, FM.; Schreier, G.

2010-01-01

Objective Results of the Austrian MOBITEL (MOBIle phone based TELemonitoring for heart failure patients) trial indicate that home-based telemonitoring improves outcome of chronic heart failure (CHF) patients and reduces both frequency and duration of hospitalizations. Based on lessons learned, we assessed the weak points to clear the way for routine operations. Methods We analyzed the system with respect to recommendations of the ESC Guidelines and experiences gained throughout the trial to identify potential improvements. The following components have been identified: a patient terminal with highest usability, integrated way to document drug-intake and well-being, and automated event detection for worsening of CHF. As a consequence the system was extended by Near Field Communication (NFC) technology and by an event management tool. Results Usability evaluation with 30 adults (14f, median 51y. IQR[45-65]) showed that 21 (8f) were able to immediately operate the system after reading a step-by-step manual. Eight (6f) needed one time demonstration and one man (80y) failed to operate the blood pressure meter. Routine operation of the revised system started in March 2009. Within 9 months, 15 patients (4f, median 74y. IQR[71-83], all NYHA-III) transmitted 17,149 items. 43 events were detected because of body weight gain of more then 2kg within 2 days. 49 therapy adjustments were documented. Three patients stopped using the system, two (1f) because of non-compliance and one (m, 82y) because of death. Overall, the rate of adherence to daily data transfer was 78%. Conclusion First results confirm the applicability of the revised telemonitoring system in routine operation. PMID:23616835

Nicotinic α4β2 receptor imaging agents. Part III. Synthesis and biological evaluation of 3-(2-(S)-azetidinylmethoxy)-5-(3′-18F-fluoropropyl)pyridine (18F-nifzetidine)

International Nuclear Information System (INIS)

Pichika, Rama; Easwaramoorthy, Balu; Christian, Bradley T.; Shi, Bingzhi; Narayanan, Tanjore K.; Collins, Daphne; Mukherjee, Jogeshwar

2011-01-01

Thalamic and extrathalamic nicotinic α4β2 receptors found in the brain have been implicated in Alzheimer's disease, Parkinson's disease, substance abuse and other disorders. We report here the development of 3-(2-(S)-azetidinylmethoxy)-5-(3′-fluoropropyl)pyridine (nifzetidine) as a new putative high-affinity antagonist for nicotinic α4β2 receptors. Nifzetidine in rat brain homogenate assays containing α4β2 sites labeled with 3 H-cytisine exhibited a binding affinity: Ki=0.67 nM. The fluorine-18 analog, 3-(2-(S)-azetidinylmethoxy)-5-(3′- 18 F-fluoropropyl)pyridine ( 18 F-nifzetidine), was synthesized in 20%–40% yield, and apparent specific activity was estimated to be above 2 Ci/μmol. Rat brain slices indicated selective binding of 18 F-nifzetidine to thalamus, subiculum, striata, cortex and other regions consistent with α4β2 receptor distribution. This selective binding was displaced >85% by 150 μM nicotine. Positron emission tomography (PET) imaging studies of 18 F-nifzetidine in anesthetized rhesus monkey showed slow uptake in the various brain regions. Retention of 18 F-nifzetidine was maximal in the thalamus and lateral geniculate followed by regions of the temporal and frontal cortex. Cerebellum showed the least uptake. Thalamus to cerebellum ratio was about 2.3 at 180 min postinjection and continued to rise. 18 F-Nifzetidine shows promise as a new PET imaging agent for α4β2 nAChR. However, the slow kinetics suggests a need for >3-h PET scans for quantitative studies of the α4β2 nAChRs.

GdF-Suez. The challenges of a merger

International Nuclear Information System (INIS)

Lepetit, V.

2007-01-01

After 18 months of stamping, the GdF-Suez merger is finally started. This operation will lead to the creation of a major actor of the European energy scene in particular for natural gas and LNG. This paper reviews the stakes of this merger in terms of employment and its impacts on energy prices and markets. One goal of this merger is to gain market shares in electricity and to compete with EdF (Electricite de France), the French electric utility. (J.S.)

TS-05: 150 lines of java with high architectural complexity

DEFF Research Database (Denmark)

Christensen, Henrik Bærbak

2005-01-01

In the short time span available in a software architecture course, it is difficult to find a software system that is both interesting from an architectural perspective and so small that it does not overwhelm the students.We present TS-05 which is a bare 150 line Java "toy-system" that never...

21 CFR 163.150 - Sweet cocoa and vegetable fat coating.

Science.gov (United States)

2010-04-01

... preparation of the product, cocoa or a mixture of cocoa and chocolate liquor is used in such quantity that the... 21 Food and Drugs 2 2010-04-01 2010-04-01 false Sweet cocoa and vegetable fat coating. 163.150... (CONTINUED) FOOD FOR HUMAN CONSUMPTION CACAO PRODUCTS Requirements for Specific Standardized Cacao Products...

Weighted Composition Operators from Hardy Spaces into Logarithmic Bloch Spaces

Directory of Open Access Journals (Sweden)

Flavia Colonna

2012-01-01

Full Text Available The logarithmic Bloch space Blog⁡ is the Banach space of analytic functions on the open unit disk 𝔻 whose elements f satisfy the condition ∥f∥=sup⁡z∈𝔻(1-|z|2log⁡  (2/(1-|z|2|f'(z|<∞. In this work we characterize the bounded and the compact weighted composition operators from the Hardy space Hp (with 1≤p≤∞ into the logarithmic Bloch space. We also provide boundedness and compactness criteria for the weighted composition operator mapping Hp into the little logarithmic Bloch space defined as the subspace of Blog⁡ consisting of the functions f such that lim⁡|z|→1(1-|z|2log⁡  (2/(1-|z|2|f'(z|=0.

Effect of gamma radiation at pupal stage on fall army worm parent and F1 generation reproduction

International Nuclear Information System (INIS)

Arthur, V.; Maximiliano Wiendl, F.M.; Duarte Aguilar, J.A.; Domarco, R.E.

1993-01-01

To induce sterility in the F 1 generation, pupae of the fall army worm, Spodoptera frugiperda (J.E. Smith), were irradiated at the age of five days. The radiation source was a 60 Co panoramic irradiator. The pupae were irradiated at the dose rate of 2.60 kGy/h with doses of 0 (control), 50, 75, 100 and 125 Gy. The percentage hatch of eggs laid by adults that originated from pupae irradiated with 125 Gy was 15.0 and 10.0% for males and females, respectively. By crossing this irradiated parent generation, it was found that the egg hatch in the F 1 generation was 4% for descendants of treated males and 10% for descendants of treated females. (author). 12 refs, 2 figs, 2 tabs

Identification of Success Criteria for Automated Function Using Feed and Bleed Operation

International Nuclear Information System (INIS)

Kim, Bo Gyung; Kim, Sang Ho; Kang, Hyun Gook; Yoon, Ho Joon

2013-01-01

Since NPP has lots of functions and systems, operated procedure is much complicated and the chance of human error to operate the safety systems is quite high. In the case of large break loss of coolant accident (LBLOCA) and station black out (SBO), the dependency of operator is very low. However, when many mitigation systems are still available, operators have several choices to mitigate the accident and the human error can be increased more. To reduce the operator's workload and perform the operation accurate after the accident, automated function for safe cooldown based on the feed and bleed (F and B) operation was suggested. The automated function can predict whether the plant will be safe after the automated function is initiated, and perform the safety functions automatically. To expect the success of cooldown, success criteria should be identified. To perform the operation accurately after the accident, the automated function for safe cooldown based on the F and B operation is suggested. To expect the success of cooldown, sequence of RCS situation when heat removal by secondary system fails is identified. Based on the sequence of RCS situation, four levels of necessity of F and B operation are classified. To obtain the boundary of levels, the TH analysis will be performed

F4 symmetric ϕ3 theory at four loops

Science.gov (United States)

Gracey, J. A.

2017-03-01

The renormalization group functions for six dimensional scalar ϕ3 theory with an F4 symmetry are provided at four loops in the modified minimal subtraction (MS ¯ ) scheme. Aside from the anomalous dimension of ϕ and the β -function this includes the mass operator and a ϕ2-type operator. The anomalous dimension of the latter is computed explicitly at four loops for the 26 and 324 representations of F4. The ɛ expansion of all the related critical exponents are determined to O (ɛ4). For instance the value for Δϕ agrees with recent conformal bootstrap estimates in 5 and 5.95 dimensions. The renormalization group functions are also provided at four loops for the group E6.

Etude des paramètres opératoires de pressage mécanique des amandes de Vitellaria paradoxa Gaertn C.F. (karité

Directory of Open Access Journals (Sweden)

Destain MF.

2007-01-01

Full Text Available Study of the operational parameters of mechanical pressing of almonds of Vitellaria paradoxa Gaertn C.F. (shea tree. Sheabutter is one of the most difficult oleaginous resources to extract by traditional way. In Burkina Faso, where production of sheanuts is estimated at 70000 tons per year, presses manufactured locally are used to improve the production. In order to optimize the handcraft process of sheabutter production, extraction parameters of Vitellaria paradoxa Gaertn C.F. were studied under laboratory controlled conditions on 3 g samples of ground almonds using a uni-axial compression test machine specifically instrumented for this purpose. The studied operational parameters were the grinding (unsieved sample 0.5 mm<Ø<5 mm ; sieved samples 0.5 mm<Ø<1 mm ; 1 mm<Ø<2 mm ; 2 mm<Ø<4 mm ; 4 mm<Ø<5 mm, the heating temperature (30; 50; 70; 90; 110; 130; 150°C and the extraction pressure (7; 10; 13.4; 15; 16.17; 17.44; 20; 22.43 and 25 MPa. The grinding has favourably influenced the extraction rate. The finest sieved fraction (0.5 mm<Ø<1 mm presented the highest extraction rate, 84%. When using unsieved samples, the best results were obtained with a heating temperature of 90°C and an extraction pressure of 20 MPa. In these conditions, the extraction rate reached 78% and the chemical characteristics of the sheabutter were not altered. As a result, a significant increase of the handcrafted presses efficiency could be reached by simple and inexpensive modifications as an increase of the pressure applied to the product, by a decrease of the pressing chamber diameter.

Charge-state related effects in sputtering of LiF by swift heavy ions