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Sample records for eye institute nei

  1. 77 FR 63845 - National Eye Institute; Notice of Closed Meetings

    Science.gov (United States)

    2012-10-17

    ... personal privacy. Name of Committee: National Eye Institute Special Emphasis Panel; NEI-RFA Stem Cell... Extramural Research, National Eye Institute, National Institutes of Health, 5635 Fishers Lane, Suite 1300... Research, National Eye Institute, National Institutes of Health, 5635 Fishers Lane, Suite 1300, MSC 9300...

  2. Comparison of the NEI-VFQ and OSDI questionnaires in patients with Sjögren's syndrome-related dry eye

    Directory of Open Access Journals (Sweden)

    Smith Janine A

    2004-09-01

    Full Text Available Abstract Background To examine the associations between vision-targeted health-related quality of life (VT-HRQ and ocular surface parameters in patients with Sjögren's syndrome, a systemic autoimmune disease characterized by dry eye and dry mouth. Methods Forty-two patients fulfilling European / American diagnostic criteria for Sjögren's syndrome underwent Schirmer testing without anesthesia, ocular surface vital dye staining; and measurement of tear film breakup time (TBUT. Subjects were administered the Ocular Surface Disease Index (OSDI and the 25-item National Eye Institute Vision Functioning Questionnaire (NEI-VFQ. Main outcome measures included ocular surface parameters, OSDI subscales describing ocular discomfort (OSDI-symptoms, vision-related function (OSDI-function, and environmental triggers, and NEI-VFQ subscales. Results Participants (aged 31–81 y; 95% female all had moderate to severe dry eye. Associations of OSDI subscales with the ocular parameters were modest (Spearman r (ρ Conclusions Associations between conventional objective measures of dry eye and VT-HRQ were modest. The generic NEI-VFQ was similar to the disease-specific OSDI in its ability to measure the impact of Sjögren's syndrome-related dry eye on VT-HRQ.

  3. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us ... government’s National Institutes of Health (NIH), the National Eye Institute’s mission is to “conduct and support research, ...

  4. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us Visiting the NIH Campus Mission Statement As part ...

  5. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  6. Dry Eye

    Science.gov (United States)

    ... Eye » Facts About Dry Eye Listen Facts About Dry Eye Fact Sheet Blurb The National Eye Institute (NEI) ... and their families search for general information about dry eye. An eye care professional who has examined the ...

  7. Nuclear Energy Institute (NEI) summary

    International Nuclear Information System (INIS)

    2001-01-01

    The Nuclear Energy Institute (NEI) provided a brief discussion on the benefits of establishing a new regulatory framework. He suggested that a new paradigm in regulatory thinking is needed and stated that the reactor oversight process (ROP) serves as the appropriate basis for starting these discussions. He suggested that the ROP cornerstones of safety be used as the starting point for developing a new set of General Design Criteria (10 CFR Part 50, Appendix A). It is suggested that new operating criteria, generic risk- informed and performance-based regulations be developed with associated design-specific and regulation-specific regulatory guides

  8. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L ... (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ...

  9. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia Embedded ...

  10. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube ...

  11. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... the special health problems and requirements of the blind.” News & Events Events Calendar NEI Press Releases News ... Videos Home Age-Related Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye ...

  12. Nuclear Energy Institute (NEI) summary

    International Nuclear Information System (INIS)

    2001-01-01

    The Nuclear Energy Institute (NEI) provided a brief presentation on the state of energy demand in the United States and discussed the improving economics for new nuclear power plants. He discussed the consolidation of companies under deregulation and the ability of these larger companies to undertake large capital projects such as nuclear power plant construction. He discussed efforts under way to support a new generation of plants but noted that there needs to be greater certainty in the licensing process. He discussed infrastructure challenges in terms of people, hardware, and services to support new and current plants. He stated that there needs to be fair and equitable licensing fees and decommissioning funding assurance for innovative modular designs such as the PBMR. He concluded that NRC challenges will include resolving 10 CFR Part 52 implementation issues, establishing an efficient and predictable process for siting, COL permits and inspection, and an increasing regulatory workload

  13. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... from NEI Grantees Spokesperson bios Statistics and Data ... to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  14. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  15. About the Eye

    Medline Plus

    Full Text Available ... The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips ... addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  16. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  17. About the Eye

    Medline Plus

    Full Text Available ... Contact Us Visiting the NIH Campus Mission Statement As part of the federal government’s National Institutes of ... Did You Know? Vision depends on your brain as much as it does on your eyes. NEI ...

  18. Is the NEI-VFQ-25 a useful tool in identifying visual impairment in an elderly population?

    Directory of Open Access Journals (Sweden)

    Wormald Richard PL

    2006-06-01

    Full Text Available Abstract Background The use of self-report questionnaires to substitute for visual acuity measurement has been limited. We examined the association between visual impairment and self reported visual function in a population sample of older people in the UK. Methods Cross sectional study of people aged more than 75 years who initially participated in a trial of health screening. The association between 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ scores and visual impairment (defined as an acuity of less than 6/18 in the better eye was examined using logistic regression. Results Visual acuity and NEI-VFQ scores were obtained from 1807 participants (aged 77 to 101 years, 36% male, from 20 general practices throughout the UK. After adjustment for age, gender, practice and NEI-VFQ sub-scale scores, those complaining of poor vision in general were 4.77 times (95% CI 3.03 to 7.53 more likely to be visually impaired compared to those who did not report difficulty. Self-reported limitations with social functioning and dependency on others due to poor vision were also associated with visual impairment (odds ratios, 2.52, 95% CI 1.55 to 4.11; 1.73, 95% CI 1.05 to 2.86 respectively. Those reporting difficulties with near vision and colour vision were more likely to be visually impaired (odds ratios, 2.32, 95% CI 1.30 to 4.15; 2.25, 95% CI 1.35 to 3.73 respectively. Other NEI-VFQ sub-scale scores were unrelated to measures of acuity. Similar but weaker odds ratios were found with reduced visual acuity (defined as less than 6/12 in the better eye. Although differences in NEI-VFQ scores were small, scores were strongly associated with visual acuity, binocular status, and difference in acuity between eyes. Conclusion NEI-VFQ questions regarding the quality of general vision, social functioning, visual dependency, near vision and colour vision are strongly and independently associated with an objective measure of visual impairment in an

  19. About the Eye

    Medline Plus

    Full Text Available ... search for current job openings visit HHS USAJobs Home >> NEI for Kids >> About the Eye Listen All ... much as it does on your eyes. NEI Home Contact Us A-Z Site Map NEI on ...

  20. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for ...

  1. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ...

  2. About the Eye

    Medline Plus

    Full Text Available ... search for current job openings visit HHS USAJobs Home » NEI for Kids » About the Eye Listen All ... much as it does on your eyes. NEI Home Contact Us A-Z Site Map NEI on ...

  3. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  4. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is ...

  5. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  6. Vision-related quality of life assessment using the NEI-VFQ-25 in adolescents and young adults with a history of congenital cataract.

    LENUS (Irish Health Repository)

    Kirwan, Caitriona

    2013-07-22

    To assess vision-specific health-related quality of life in adolescents and young adults with a history of congenital cataract using the National Eye Institute 25-item Visual Function Questionnaire (NEI-VFQ-25).

  7. Impact of First Eye versus Second Eye Cataract Surgery on Visual Function and Quality of Life.

    Science.gov (United States)

    Shekhawat, Nakul S; Stock, Michael V; Baze, Elizabeth F; Daly, Mary K; Vollman, David E; Lawrence, Mary G; Chomsky, Amy S

    2017-10-01

    To compare the impact of first eye versus second eye cataract surgery on visual function and quality of life. Cohort study. A total of 328 patients undergoing separate first eye and second eye phacoemulsification cataract surgeries at 5 veterans affairs centers in the United States. Patients with previous ocular surgery, postoperative endophthalmitis, postoperative retinal detachment, reoperation within 30 days, dementia, anxiety disorder, hearing difficulty, or history of drug abuse were excluded. Patients received complete preoperative and postoperative ophthalmic examinations for first eye and second eye cataract surgeries. Best-corrected visual acuity (BCVA) was measured 30 to 90 days preoperatively and postoperatively. Patients completed the National Eye Institute Visual Functioning Questionnaire (NEI-VFQ) 30 to 90 days preoperatively and postoperatively. The NEI-VFQ scores were calculated using a traditional subscale scoring algorithm and a Rasch-refined approach producing visual function and socioemotional subscale scores. Postoperative NEI-VFQ scores and improvement in NEI-VFQ scores comparing first eye versus second eye cataract surgery. Mean age was 70.4 years (±9.6 standard deviation [SD]). Compared with second eyes, first eyes had worse mean preoperative BCVA (0.55 vs. 0.36 logarithm of the minimum angle of resolution (logMAR), P < 0.001), greater mean BCVA improvement after surgery (-0.50 vs. -0.32 logMAR, P < 0.001), and slightly worse postoperative BCVA (0.06 vs. 0.03 logMAR, P = 0.039). Compared with first eye surgery, second eye surgery resulted in higher postoperative NEI-VFQ scores for nearly all traditional subscales (P < 0.001), visual function subscale (-3.85 vs. -2.91 logits, P < 0.001), and socioemotional subscale (-2.63 vs. -2.10 logits, P < 0.001). First eye surgery improved visual function scores more than second eye surgery (-2.99 vs. -2.67 logits, P = 0.021), but both first and second eye surgeries resulted in similar

  8. About the Eye

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us Visiting the NIH Campus Mission Statement As part ...

  9. Development of an Arabic version of the National Eye Institute Visual Function Questionnaire as a tool to study eye diseases patients in Egypt

    Directory of Open Access Journals (Sweden)

    Nizar Saleh Abdelfattah

    2014-10-01

    Full Text Available AIM:To develop and test an Arabic version of the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25.METHODS:NEI-VFQ-25 was translated into Arabic according to WHO translation guidelines. We enrolled adult consenting patients with bilateral chronic eye diseases who presented to 14 hospitals across Egypt from October to December 2012, and documented their clinical findings. Psychometric properties were then tested using STATA.RESULTS:We recruited 379 patients, whose mean age was (54.5±15y. Of 46.2% were males, 227 had cataract, 31 had glaucoma, 23 had retinal detachment, 37 had diabetic retinopathy, and 61 had miscellaneous visual defects. Non-response rate and the floor and ceiling numbers of the Arabic version (ARB-VFQ-25 were calculated. Internal consistency was high in all subscales (except general health, with Cronbach-α ranging from 0.702-0.911. Test-retest reliability was high (intraclass correlation coefficient 0.79.CONCLUSION:ARB-VFQ-25 is a reliable and valid tool for assessing visual functions of Arabic speaking patients. However, some questions had high non-response rates and should be substituted by available alternatives. Our results support the importance of including self-reported visual functions as part of routine ophthalmologic examination.

  10. National Eye Institute

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  11. About the Eye

    Medline Plus

    Full Text Available ... History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  12. About the Eye

    Medline Plus

    Full Text Available ... Learn how the different parts of your eye work together so you can see and make sense of the world around you. Did You Know? Vision depends on your brain as much as it does on your eyes. NEI Home Contact Us A-Z Site Map NEI on ...

  13. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Search the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ...

  14. About the Eye

    Medline Plus

    Full Text Available ... the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L ... (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ...

  15. About the Eye

    Medline Plus

    Full Text Available ... System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear ... Social Media Policies and Other Important Links NEI Employee Emergency Information NEI Intranet (Employees Only) *PDF files ...

  16. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... visual function, preservation of sight, and the special health problems and requirements of the blind.” News & Events Events ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. ... of Health and Human Services | The National Institutes of Health | ...

  17. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National ...

  18. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ...

  19. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available Skip to main content Search Search: Search Search Search the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research Accomplishments ...

  20. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... YouTube Videos » NEI YouTube Videos: Amblyopia Listen NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration ... Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia Embedded video for NEI YouTube Videos: ...

  1. Assessing the test-retest repeatability of the Vietnamese version of the National Eye Institute 25-item Visual Function Questionnaire among bilateral cataract patients for a Vietnamese population.

    Science.gov (United States)

    To, Kien Gia; Meuleners, Lynn; Chen, Huei-Yang; Lee, Andy; Do, Dung Van; Duong, Dat Van; Phi, Tien Duy; Tran, Hoang Huy; Nguyen, Nguyen Do

    2014-06-01

    To determine the test-retest repeatability of the National Eye Institute 25-item Visual Function Questionnaire (NEI VFQ-25) for use with older Vietnamese adults with bilateral cataract. The questionnaire was translated into Vietnamese and back-translated into English by two independent translators. Patients with bilateral cataract aged 50 and older completed the questionnaire on two separate occasions, one to two weeks after first administration of the questionnaire. Test-retest repeatability was assessed using the Cronbach's α and intraclass correlation coefficients. The average age of participants was 67 ± 8 years and most participants were female (73%). Internal consistency was acceptable with the α coefficient above 0.7 for all subscales and intraclass correlation coefficients were 0.6 or greater in all subscales. The Vietnamese NEI VFQ-25 is reliable for use in studies assessing vision-related quality of life in older adults with bilateral cataract in Vietnam. We propose some modifications to the NEI-VFQ questions to reflect activities of older people in Vietnam. © 2013 ACOTA.

  2. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube Videos: Amblyopia Embedded video for NEI YouTube Videos: Amblyopia NEI Home Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  3. About the Eye

    Medline Plus

    Full Text Available ... First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about ...

  4. About the Eye

    Medline Plus

    Full Text Available ... the special health problems and requirements of the blind.” News & Events Events Calendar NEI Press Releases News ... First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks ...

  5. About the Eye

    Medline Plus

    Full Text Available ... Home » NEI for Kids » About the Eye Listen All About Vision About the Eye Ask a Scientist ... you can see and make sense of the world around you. Did You Know? Vision depends on ...

  6. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... search for current job openings visit HHS USAJobs Home >> NEI YouTube Videos >> NEI YouTube Videos: Amblyopia Listen NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration Amblyopia Animations Blindness Cataract ...

  7. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... search for current job openings visit HHS USAJobs Home » NEI YouTube Videos » NEI YouTube Videos: Amblyopia Listen NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration Amblyopia Animations Blindness Cataract ...

  8. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Search Search the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  9. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... NEI on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research ... on Social Media Information in Spanish (Información en español) Website, Social Media Policies and Other Important Links ...

  10. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Search Search the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, Social ...

  11. National Emission Inventory (NEI)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This data exchange allows states to submit data to the US Environmental Protection Agency's National Emissions Inventory (NEI). NEI is a national database of air...

  12. NEI for Kids: Glossary

    Science.gov (United States)

    ... a cornea that is curved more like a football, with some areas that are steeper or more ... Media Policies and Other Important Links NEI Employee Emergency Information NEI Intranet (Employees Only) *PDF files require ...

  13. About the Eye

    Medline Plus

    Full Text Available ... from NEI Grantees Spokesperson bios Statistics and Data ... to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  14. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... blind.” News & Events Events Calendar NEI Press Releases News from NEI Grantees Spokesperson bios Statistics and Data Resources for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin. ...

  15. Comparison of scoring approaches for the NEI VFQ-25 in low vision.

    Science.gov (United States)

    Dougherty, Bradley E; Bullimore, Mark A

    2010-08-01

    The aim of this study was to evaluate different approaches to scoring the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25) in patients with low vision including scoring by the standard method, by Rasch analysis, and by use of an algorithm created by Massof to approximate Rasch person measure. Subscale validity and use of a 7-item short form instrument proposed by Ryan et al. were also investigated. NEI VFQ-25 data from 50 patients with low vision were analyzed using the standard method of summing Likert-type scores and calculating an overall average, Rasch analysis using Winsteps software, and the Massof algorithm in Excel. Correlations between scores were calculated. Rasch person separation reliability and other indicators were calculated to determine the validity of the subscales and of the 7-item instrument. Scores calculated using all three methods were highly correlated, but evidence of floor and ceiling effects was found with the standard scoring method. None of the subscales investigated proved valid. The 7-item instrument showed acceptable person separation reliability and good targeting and item performance. Although standard scores and Rasch scores are highly correlated, Rasch analysis has the advantages of eliminating floor and ceiling effects and producing interval-scaled data. The Massof algorithm for approximation of the Rasch person measure performed well in this group of low-vision patients. The validity of the subscales VFQ-25 should be reconsidered.

  16. About the Eye

    Medline Plus

    Full Text Available ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  17. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision ... DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home >> NEI YouTube Videos >> ...

  18. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website ...

  19. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Amblyopia Listen NEI YouTube Videos YouTube Videos Home Age-Related Macular Degeneration Amblyopia Animations Blindness Cataract Convergence ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this ...

  20. NEI You Tube Videos: Amblyopia

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  1. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision ... DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home » NEI YouTube Videos » ...

  2. About the Eye

    Medline Plus

    Full Text Available ... Learn how the different parts of your eye work together so you can see and make sense of the world around you. ... Social Media Policies and Other Important Links NEI Employee Emergency Information ...

  3. About the Eye

    Medline Plus

    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  4. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  5. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ... This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website ...

  6. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Program Vision and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home >> NEI YouTube Videos >> ...

  7. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Program Vision and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home » NEI YouTube Videos » ...

  8. About the Eye

    Medline Plus

    Full Text Available ... NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ... for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media ...

  9. About the Eye

    Medline Plus

    Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ... Employee Emergency Information NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. ...

  10. About the Eye

    Medline Plus

    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for ...

  11. About the Eye

    Medline Plus

    Full Text Available ... blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ...

  12. About the Eye

    Medline Plus

    Full Text Available ... with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  13. About the Eye

    Medline Plus

    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is ...

  14. About the Eye

    Medline Plus

    Full Text Available ... the white outer coating of the eye. Vitreous humor (VIT-ree-us HYOO-mer) is the clear ... in Spanish (Información en español) Website, Social Media Policies and Other Important Links NEI Employee Emergency Information ...

  15. About the Eye

    Medline Plus

    Full Text Available ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  16. Punctal Plug Retention Rates for the Treatment of Moderate to Severe Dry Eye: A Randomized, Double-Masked, Controlled Clinical Trial.

    Science.gov (United States)

    Brissette, Ashley R; Mednick, Zale D; Schweitzer, Kelly D; Bona, Mark D; Baxter, Stephanie A

    2015-08-01

    To compare retention rates of Super Flex (Eagle Vision, Memphis, Tennessee, USA; Softplug-Oasis Medical Inc, Glendora, California, USA) vs Parasol (Odyssey Medical, Memphis, Tennessee, USA; Beaver Visitec International, Waltham, Massachusetts, USA) punctal plugs. Randomized, double-masked, interventional controlled clinical trial. Institutional study at Hotel Dieu Hospital (Queen's University) of 50 eyes, from patients with moderate to severe dry eye. Each eye from eligible patients was separately randomized to receive Super Flex or Parasol punctal plugs. The main outcome measure was plug retention at 6 months. Secondary outcome measures included objective tests of Schirmer I (mm), tear meniscus height (mm), tear break-up time (s), inferior fluorescein corneal staining (National Eye Institute [NEI] scale), and average lissamine green conjunctival staining (NEI scale). Punctal plug retention was significantly different at 6 months (P = .011). Sixty-eight percent of Parasol plugs were retained compared to 32% of Super Flex plugs. Parasol plugs required less frequent artificial tear use at 6 months (P = .024). There was a statistically significant improvement in all secondary outcome measures (Schirmer, tear meniscus height, tear break-up time, fluorescein corneal staining) at 6 months within plug groups except conjunctival staining. There were no additional significant differences between groups and no plug complications reported. Punctal plugs improve symptoms of moderate to severe dry eye; however, retention rates differ significantly. These data will allow us to guide patient decision making for the safe and effective treatment of punctal plugs for moderate to severe dry eye. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Neuropeptide glutamic acid-isoleucine (NEI)-induced paradoxical sleep in rats.

    Science.gov (United States)

    Fujimoto, Moe; Fukuda, Satoru; Sakamoto, Hidetoshi; Takata, Junko; Sawamura, Shigehito

    2017-01-01

    Neuropeptideglutamic acid-isoleucine (NEI) as well as melanin concentrating hormone (MCH) is cleaved from the 165 amino acid protein, prepro-melanin concentrating hormone (prepro-MCH). Among many physiological roles of MCH, we demonstrated that intracerebroventricular (icv) injection of MCH induced increases in REM sleep episodes as well as in non REM sleep episodes. However, there are no studies on the effect of NEI on the sleep-wake cycle. As for the sites of action of MCH for induction of REM sleep, the ventrolateral periaqueductal gray (vlPAG) has been reported to be one of its site of action. Although MCH neurons contain NEI, GABA, MCH, and other neuropeptides, we do not know which transmitter(s) might induce REM sleep by acting on the vlPAG. Thus, we first examined the effect of icv injection of NEI on the sleep-wake cycle, and investigated how microinjection of either NEI, MCH, or GABA into the vlPAG affected REM sleep in rats. Icv injection of NEI (0.61μg/5μl: n=7) significantly increased the time spent in REM episodes compared to control (saline: 5μl; n=6). Microinjection of either NEI (61ng/0.2μl: n=7), MCH (100ng/0.2μl: n=6) or GABA (250mM/0.2μl: n=7) into the vlPAG significantly increased the time spent in REM episodes and the AUC. Precise hourly analysis of REM sleep also revealed that after those microinjections, NEI and MCH increased REM episodes at the latter phase, compared to GABA which increased REM episodes at the earlier phase. This result suggests that NEI and MCH may induce sustained REM sleep, while GABA may initiate REM sleep. In conclusion, our findings demonstrate that NEI, a cleaved peptide from the same precursor, prepro-MCH, as MCH, induce REM sleep at least in part through acting on the vlPAG. Copyright © 2016 Elsevier Inc. All rights reserved.

  18. Low Vision Research at the Schepens Eye Research Institute

    National Research Council Canada - National Science Library

    D'Amore, Patricia

    2003-01-01

    This research proposal, Low Vision at the Schepens Eye Research Institute, is a collaborative effort on the part of four Investigators at the Institute whose goal is to advance the studies on low vision...

  19. Impact of Dry Eye Syndrome on Vision-Related Quality of Life in a Non-Clinic-Based General Population

    Directory of Open Access Journals (Sweden)

    Le Qihua

    2012-07-01

    Full Text Available Abstract Background Dry eye syndrome (DES is a common ocular disorder occurring in general population. The purpose of this study is to evaluate the impact of DES on vision-related quality of life (QoL in a non-clinic-based general population. Methods This population-based cross-sectional study enrolled subjects older than 40 years, who took part in an epidemiological study on dry eye in Sanle Community, Shanghai. Apart from the collection of sociodemographics, dry eye symptoms, and other clinical data, a Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25 was administered to all subjects. Comparisons of the NEI VFQ-25 subscale item scores and composite score were made among subgroups divided according to the presence of dry eye symptoms or signs. Multivariate regression analysis was performed to investigate the relationship between the clinical variables and the VFQ-25 composite score. Results A total of 229 participants were enrolled in the study, with an average age of (60.7 ±10.1 years old. Majority of these participants were female (59.8 %, 137/229. The total DES symptom scores (TDSS in subjects either with definite DES or only with dry eye symptoms were significantly higher (F = 60.331, P  Conclusions The symptoms of dry eye are associated with an adverse impact on vision-related QoL in non-clinic-based general population, which is mainly represented as more ocular pain and discomfort, and impaired mental health as well. Apart from clinical examination, it is also important to refer to subjective symptoms and QoL scores when assessing the severity of DES.

  20. NEI You Tube Videos: Amblyopia

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  1. NEI You Tube Videos: Amblyopia

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    Full Text Available ... Studies Publications Catalog Photos and Images Spanish Language Information Grants and Funding Extramural Research Division of Extramural Science Programs Division of Extramural Activities Extramural Contacts NEI ...

  2. NEI You Tube Videos: Amblyopia

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    Full Text Available ... Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino ... To search for current job openings visit HHS USAJobs Home » NEI YouTube ...

  3. 78 FR 28233 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2013-05-14

    ..., National Eye Institute, Bethesda, MD 20892, (301) 451-6763. In the interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and...

  4. Eye Care Professionals' Perspectives on Eye Donation and an Eye Donation Registry for Research: A Single-Institution, Cross-Sectional Study.

    Science.gov (United States)

    Williams, Andrew M; Allingham, R Rand; Stamer, W Daniel; Muir, Kelly W

    2016-06-01

    A centralized eye donation registry for research could help to bridge the gap between patients interested in donating their eyes to science and scientists who conduct research on human eye tissue. Previous research has demonstrated patient and family support for such a registry. In this study, we assessed the views that eye care professionals have toward an eye donation registry for research. Surveys were distributed to all 46 clinical faculty members of the Duke University Eye Center. In addition to collecting demographic information, the surveys assessed clinicians' experience with discussing eye donation with patients, described the proposed eye donation registry for research and asked how the registry would affect the clinicians' practice. A total of 21 eye care professionals returned the survey. Thirty-three percent reported discussing eye donation with patients, and 43% reported that a patient has asked about donating their eyes for research on their disease. Eighty-six percent of eye care professionals reported that a centralized registry would improve the way they work with patients who express a desire to donate their eyes for research. The majority of eye care professionals at our academic institution indicated that an eye donation registry for research would improve how they work with patients who are interested in donating their eyes for research on their disease. Future research should examine how best to communicate this registry to ophthalmic patients.

  5. NEI You Tube Videos: Amblyopia

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  6. NEI You Tube Videos: Amblyopia

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  7. NEI You Tube Videos: Amblyopia

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  8. NEI You Tube Videos: Amblyopia

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  9. About the Eye

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    Full Text Available ... Lane, MSC 9300 Bethesda, MD 20892-9300 (Courier services use: Rockville, MD 20852) 301-451-2020 Research ... NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH… ...

  10. NEI You Tube Videos: Amblyopia

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  11. Functional Visual Improvement After Cataract Surgery in Eyes With Age-Related Macular Degeneration: Results of the Ophthalmic Surgical Outcomes Data Project.

    Science.gov (United States)

    Stock, Michael V; Vollman, David E; Baze, Elizabeth F; Chomsky, Amy S; Daly, Mary K; Lawrence, Mary G

    2015-04-01

    To determine if cataract surgery on eyes with AMD confers as much functional visual improvement as surgery on eyes without retinal pathology. This is a retrospective analysis of 4924 cataract surgeries from the Veterans Healthcare Administration Ophthalmic Surgical Outcomes Data Project (OSOD). We included cases of eyes with AMD that had both preoperative and postoperative NEI-VFQ-25 questionnaires submitted and compared their outcomes with controls without retinal pathology. We excluded patients with other retinal pathologies (740 patients). The analyses compared changes in visual acuity and overall functional visual improvement and its subscales using t-tests, multivariate logistic regressions, and linear regression modeling. Preoperative and postoperative questionnaires were submitted by 58.3% of AMD and 63.8% of no retinal pathology cases (controls). Analysis of overall score showed that cataract surgery on eyes with AMD led to increased visual function (13.8 ± 2.4 NEI-VFQ units, P < 0.0001); however, increases were significantly less when compared with controls (-6.4 ± 2.9 NEI-VFQ units, P < 0.0001). Preoperative best-corrected visual acuity (preBCVA) in AMD was predictive of postoperative visual function (r = -0.38, P < 0.0001). In controls, postoperative visual function was only weakly associated with preBCVA (r = -0.075, P = 0.0002). Patients with AMD with vision of 20/40 or better had overall outcomes similar to controls (-2.2 ± 4.7 NEI-VFQ units, P = 0.37). Cataract surgery on eyes with AMD offers an increase in functional visual improvement; however, the amount of benefit is associated with the eye's preBCVA. For eyes with preBCVA of 20/40 or greater, the improvement is similar to that of patients without retinal pathology. However, if preBCVA is less than 20/40, the amount of improvement was shown to be significantly less and decreased with decreasing preBCVA.

  12. The contribution of Nth and Nei DNA glycosylases to mutagenesis in Mycobacterium smegmatis.

    Science.gov (United States)

    Moolla, Nabiela; Goosens, Vivianne J; Kana, Bavesh D; Gordhan, Bhavna G

    2014-01-01

    The increased prevalence of drug resistant strains of Mycobacterium tuberculosis (Mtb) indicates that significant mutagenesis occurs during tuberculosis disease in humans. DNA damage by host-derived reactive oxygen/nitrogen species is hypothesized to be critical for the mutagenic process in Mtb thus, highlighting an important role for DNA repair enzymes in maintenance of genome fidelity. Formamidopyrimidine (Fpg/MutM/Fapy) and EndonucleaseVIII (Nei) constitute the Fpg/Nei family of DNA glycosylases and together with EndonucleaseIII (Nth) are central to the base excision repair pathway in bacteria. In this study we assess the contribution of Nei and Nth DNA repair enzymes in Mycobacterium smegmatis (Msm), which retains a single nth homologue and duplications of the Fpg (fpg1 and fpg2) and Nei (nei1 and nei2) homologues. Using an Escherichia coli nth deletion mutant, we confirm the functionality of the mycobacterial nth gene in the base excision repair pathway. Msm mutants lacking nei1, nei2 and nth individually or in combination did not display aberrant growth in broth culture. Deletion of nth individually results in increased UV-induced mutagenesis and combinatorial deletion with the nei homologues results in reduced survival under oxidative stress conditions and an increase in spontaneous mutagenesis to rifampicin. Deletion of nth together with the fpg homolgues did not result in any growth/survival defects or changes in mutation rate. Furthermore, no differential emergence of the common rifampicin resistance conferring genotypes were noted. Collectively, these data confirm a role for Nth in base excision repair in mycobacteria and further highlight a novel interplay between the Nth and Nei homologues in spontaneous mutagenesis. Copyright © 2013 Elsevier B.V. All rights reserved.

  13. NEI You Tube Videos: Amblyopia

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    Full Text Available ... the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications (301)496-5248 Health Information Frequently asked questions ...

  14. NEI You Tube Videos: Amblyopia

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  15. NEI You Tube Videos: Amblyopia

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    Full Text Available ... is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding ... NEI Office of Communications (301)496-5248 Health Information Frequently asked questions Clinical Studies Publications Catalog Photos ...

  16. NEI You Tube Videos: Amblyopia

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    Full Text Available ... for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media ... Grants and Funding Extramural Research Division of Extramural Science Programs Division of Extramural Activities Extramural Contacts NEI ...

  17. About the Eye

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    Full Text Available ... Search the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ...

  18. Dry eye in the beaver dam offspring study: prevalence, risk factors, and health-related quality of life.

    Science.gov (United States)

    Paulsen, Adam J; Cruickshanks, Karen J; Fischer, Mary E; Huang, Guan-Hua; Klein, Barbara E K; Klein, Ronald; Dalton, Dayna S

    2014-04-01

    To estimate dry eye prevalence in the Beaver Dam Offspring Study (BOSS), including a young adult population, and investigate associated risk factors and impact on health-related quality of life. Cohort study. The BOSS (2005-2008) is a study of aging in the adult offspring of the population-based Epidemiology of Hearing Loss Study cohort. Questionnaire data on health history, medication use, risk factors, and quality of life were available for 3275 participants. Dry eye was determined by self-report of frequency of symptoms and the intensity of those symptoms. Associations between dry eye and risk factors were analyzed using logistic regression. The prevalence of dry eye in the BOSS was 14.5%: 17.9% of women and 10.5% of men. In a multivariate model, statistically significant associations were found with female sex (odds ratio [OR], 1.68; 95% confidence interval [CI], 1.33-2.11), current contact lens use (OR, 2.01; 95% CI, 1.53-2.64), allergies (OR, 1.59; 95% CI, 1.22-2.08), arthritis (OR, 1.44; 95% CI, 1.12-1.85), thyroid disease (OR, 1.43; 95% CI, 1.02-1.99), antihistamine use (OR, 1.54; 95% CI, 1.18-2.02), and steroid use (OR, 1.54; 95% CI, 1.16-2.06). Dry eye was also associated with lower scores on the Medical Outcomes Study Short Form 36 (β = -3.9, P < .0001) as well as on the National Eye Institute 25-Item Visual Function Questionnaire (NEI VFQ-25) (β = -3.4, P < .0001) when controlling for age, sex, and comorbid conditions. The prevalence of dry eye and its associated risk factors in the BOSS were similar to previous studies. In this study, dry eye was associated with lower quality of life on a health-related quality-of-life instrument and the vision-specific NEI VFQ-25. Copyright © 2014 Elsevier Inc. All rights reserved.

  19. NEI You Tube Videos: Amblyopia

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  20. NEI You Tube Videos: Amblyopia

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    Full Text Available ... for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this ...

  1. NEI You Tube Videos: Amblyopia

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    Full Text Available ... part of the federal government’s National Institutes of Health (NIH), the National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to ...

  2. NEI You Tube Videos: Amblyopia

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    Full Text Available ... Campus Mission Statement As part of the federal government’s National Institutes of Health (NIH), the National Eye ... Publications Catalog Photos and Images Spanish Language Information Grants and Funding Extramural Research Division of Extramural Science ...

  3. About the Eye

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    Full Text Available ... visual function, preservation of sight, and the special health problems and requirements of the blind.” News & Events Events ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. ... of Health and Human Services | The National Institutes of Health | ...

  4. About the Eye

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    Full Text Available ... on Social Media | Search A-Z | en español | Text size S M L About NEI NEI Research Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National ...

  5. Knowledge, Attitude, and Practice of Dry Eye Treatment by Institutional Chinese Physicians in Singapore

    Science.gov (United States)

    Lan, Wanwen; Lee, Sze Yee; Lee, Man Xin; Tong, Louis

    2012-01-01

    Dry eye is a common health problem worldwide, causing significant discomfort and inconvenience to sufferers. The conventional treatment of dry eye via topical administration of eye drops is deemed palliative and unsatisfactory to many. Traditional Chinese medicine (TCM) has shown some promise in dry eye treatment; however, the extent of its use and acceptance is uncertain. We evaluated the knowledge, attitude, and practice of institutional TCM practitioners in the treatment of dry eye in Singapore. A questionnaire was generated to address the study aims and sent to TCM practitioners listed in the Singapore TCM practitioners' board database. About three quarters of respondents thought that dry eye was not severe enough to be a public health burden but most thought that TCM was effective in the treatment of dry eye. Acupuncture and herbal medicine were most commonly used TCM modalities in dry eye treatment, and a single TCM treatment session would be charged S$20–50 by the practitioner. The majority of surveyed institutional TCM practitioners in Singapore believe that TCM is relevant in dry eye treatment. Public awareness should be raised regarding the availability of TCM as alternative medicine for dry eye. PMID:23213306

  6. Knowledge, Attitude, and Practice of Dry Eye Treatment by Institutional Chinese Physicians in Singapore

    OpenAIRE

    Lan, Wanwen; Lee, Sze Yee; Lee, Man Xin; Tong, Louis

    2012-01-01

    Dry eye is a common health problem worldwide, causing significant discomfort and inconvenience to sufferers. The conventional treatment of dry eye via topical administration of eye drops is deemed palliative and unsatisfactory to many. Traditional Chinese medicine (TCM) has shown some promise in dry eye treatment; however, the extent of its use and acceptance is uncertain. We evaluated the knowledge, attitude, and practice of institutional TCM practitioners in the treatment of dry eye in Sing...

  7. About the Eye

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    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ...

  8. About the Eye

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  9. Counter-Democratic Surveillance: The Watchful Eye of a Local Institution

    DEFF Research Database (Denmark)

    Hjelholt, Morten

    2014-01-01

    mechanisms similar to those described by Foucault, but in the service of society. From this perspective democracy is seen as a composite of two realms – a sphere of electoral representation and a constellation of counter-democratic organizations – in constant tension with each other (Rosanvallon 2008......). The watchful eyes of counter-democratic organizations are particularly made powerful by the rise of the Internet with its spontaneous adaption of watchful functions. However increased awareness and mistrust have led not to broader participation in traditional liberal institutions but to a greater social...... in the interest of the national overseers but correspondingly given as responds to fulfill legal requirements or more loosely defined public concerns. Consequently the watchful eye of a local institution form a counter-democratic sight aimed at the strategic intentions of the Government. The paper introduces...

  10. Glaucoma

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    Full Text Available ... Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us ... government’s National Institutes of Health (NIH), the National Eye Institute’s mission is to “conduct and support research, ...

  11. Prime note sulla tutela penale dei culti nei Paesi dell’Est Europa

    Directory of Open Access Journals (Sweden)

    Giovanni Cimbalo

    2011-05-01

    Full Text Available Testo della relazione tenuta al Convegno “La Carta e la Corte” (Ferrara, 27 ottobre 2007 destinata alla pubblicazione negli Atti. SOMMARIO: 1. Alcune considerazioni preliminari sullo status delle Confessioni religiose nei paesi dell’Est Europa - 2. I nuovi orientamenti del diritto penale nell’Est Europa - 3. Le norme statali in materia di tutela penale dei culti e del sentimento religioso. 3. Le norme penali relative ai culti e a al sentimento religioso prima del 1992 nei Paesi dell’Est Europa - 4. Tipologie e tecniche legislative di tutela penale dei culti dopo il 1992 nei Paesi dell’Est Europa - 5. Alcune sommarie considerazioni.

  12. Resources for eye care at secondary and tertiary level government institutions in Saudi Arabia.

    Science.gov (United States)

    Al Motowa, Saeed; Khandekar, Rajiv; Al-Towerki, Abdulelah

    2014-01-01

    To evaluate the number of healthcare personnel and equipment resources for eye care at government institutions in different administrative zones of the Kingdom of Saudi Arabia (KSA) and to recommend measures for increasing resources to address deficiencies. Data on resources (personnel and equipment) for eye care were collected from all governmental eye units in 2012. The data was regrouped by zones and administrative areas. The mid-2012 population projections were used to calculate the ophthalmologist to population ratio and optometrist to population ratio. The equipment available for eye care was reviewed. All 60 institutions in 13 administrative areas and five zones of KSA participated in this study. There were 407 ophthalmologists and 147 optometrists. The ophthalmologist to population ratio was 1:43,000 (1:12,900 in the northern zone to 1:80,300 in the western zone). By 2015, 700 ophthalmologists will be required, and by 2020, 1,100 ophthalmologists will be required. The optometrist to population ratio was 1:95,000 (1:34,100 in the northern zone to 1:146,700 in the western zone). Nearly 2,800 and 4,400 allied eye care personnel will be needed by 2015 and 2020. Diagnostic and treatment equipment such as lasers, electrophysiologic and ultrasound equipment, and fundus cameras were not available at all institutions. Data from the private sector need to be included to draw conclusions on the human resource index for eye care in the Kingdom. An unequal distribution of resources in different zones and administrative areas requires attention. Better utilization of available resources is recommended before fulfilling the demand for additional resources.

  13. Talking to Your Doctor

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    Full Text Available ... to Your Doctor , National Eye Institute (NEI) Español Aging Planning Your Doctor Visit , NIHSeniorHealth.gov Videos: Talking ... A Guide for Older People , National Institute on Aging (NIA) Talking With Your Doctor Presentation Toolkit , National ...

  14. Residencies at The Eye Institute of the Pennsylvania College of Optometry.

    Science.gov (United States)

    Alexander, Arthur H.; Klopfer, Joann

    1983-01-01

    An optometric residency program at The Eye Institute of the Pennsylvania College of Optometry that focuses on clinical training in the areas of low vision rehabilitation, pediatric optometry, visual training, behavioral vision, primary care optometry and hospital based optometry is discussed. (MSW)

  15. Ask a Scientist: What is Color Blindness?

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  16. About the Eye

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  17. About the Eye

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  18. About the Eye

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  19. Vision-Related Quality of Life in Patients with Ocular Graft-versus-Host Disease.

    Science.gov (United States)

    Saboo, Ujwala S; Amparo, Francisco; Abud, Tulio B; Schaumberg, Debra A; Dana, Reza

    2015-08-01

    To assess the vision-related quality of life (QOL) in a cohort of patients with ocular graft-versus-host disease (GVHD). Prospective study. Eighty-four patients diagnosed with chronic ocular GVHD. We assessed the vision-related QOL with the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25). The symptoms of ocular GVHD were assessed using the Ocular Surface Disease Index (OSDI) and Symptom Assessment in Dry Eye (SANDE) questionnaires. We assessed vision-related QOL with the NEI-VFQ-25 and compared the scores obtained from patients with ocular GVHD with those from a healthy population. In the ocular GVHD population, we also evaluated the associations between the NEI-VFQ-25 and the dry eye symptoms measured by the OSDI and SANDE questionnaires, age, duration of disease, best-corrected visual acuity (BCVA), corneal fluorescein staining (CFS), tear break-up time, and Schirmer test. The mean composite NEI-VFQ-25 score in patients with ocular GVHD was 76.5±17. Compared with healthy subjects, patients with ocular GVHD reported reduced scores on all NEI-VFQ-25 subscales (each P vision (P = 0.11). The NEI-VFQ-25 composite scores significantly correlated with OSDI (R = -0.81, P vision-related QOL. This study highlights the impact of ocular GVHD on the vision-related QOL, and thus the importance of comprehensive diagnosis and treatment of this condition. Copyright © 2015 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  20. Healthy Eyes

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    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  1. The Visual System

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    Full Text Available ... The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips ... addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  2. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips ... addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  3. Review of UCN 3,4 PSA model based on NEI PRA peer review process guidance, rev.0

    International Nuclear Information System (INIS)

    Yang, Joon Eon; Kang, D. I.; Kim, K. Y.; Lee, Y. H.; Jang, S. C.; Ha, J. J.; Han, S. H.; Han, S. J.; Hwang, M. J.

    2003-05-01

    Recently, under the de-regulation environment, nuclear industry has attempted various approaches to improve the economics of Nuclear Power Plants (NPP). One of these efforts is the Risk Informed/Performance-Based Operation (RIPBO). This approach uses the risk and performance information to manage the resources effectively and efficiently that are used in the operation of NPP. In RIPBO, PSA quality is one of the most important things. The nuclear industry and regulatory body of U.S.A have developed a measure to evaluate the quality of PSA. NEI (Nuclear Energy Institute) has developed a guidance called 'NEI PRA Peer Review Guidance,' and NRC (Nuclear Regulatory Committee) and ASME have developed the 'PRA Standard.' In Korea, several projects are on going now, such as the extension of AOT/STI of RPS/ESFAS, Risk-Informed In-Service Inspection (RI-ISI). However, in Korea, there have been no attempts to evaluate the quality of PSA model itself. Therefore, we cannot be sure about the quality of PSA whether or not the present PSA model can be used for the risk-informed applications such as mentioned above. We can say that the evaluation of PSA model quality is the basis for the RIPBO. In this report, we have evaluated the quality of PSA model for Ulchin 3 and 4 units based on the NEI guidance. We, also, have derived what items are to be improved to upgrade the quality of PSA model and how it can be improved. This report can be used as the base of RIPBO work in Korea. The review result based on ASME Standard is published as the separated technical report of KAERI

  4. Cataract Surgery Visual Outcomes and Associated Risk Factors in Secondary Level Eye Care Centers of L V Prasad Eye Institute, India.

    Science.gov (United States)

    Matta, Sumathi; Park, Jiwon; Palamaner Subash Shantha, Ghanshyam; Khanna, Rohit C; Rao, Gullapalli N

    2016-01-01

    To evaluate cataract surgery visual outcomes and associated risk factors in rural secondary level eye care centers of L V Prasad Eye Institute (LVPEI), India. The Eye Health pyramid of LVPEI has a network of rural secondary care centres (SCs) and attached vision centres (VCs) that provide high quality comprehensive eye care with permanent infrastructure to the most disadvantaged sections of society. The most common procedure performed at SCs is cataract surgery. We audited the outcome of a random sample of 2,049 cataract surgeries done from October 2009-March 2010 at eight rural SCs. All patients received a comprehensive ophthalmic examination, both before and after surgery. The World Health Organization recommended cataract surgical record was used for data entry. Visual outcomes were measured at discharge, 1-3 weeks and 4-11 weeks follow up visits. Poor outcome was defined as best corrected visual acuity gender discrimination in terms of outcome continues to be an issue and needs further investigation.

  5. About the Eye

    Medline Plus

    Full Text Available ... blind.” News & Events Events Calendar NEI Press Releases News from NEI Grantees Spokesperson bios Statistics and Data Resources for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin. ...

  6. Incidenza di meningiti nell'ASL di Brescia nei primi mesi del 2003

    Directory of Open Access Journals (Sweden)

    M. Magoni

    2003-05-01

    Full Text Available

    Obiettivi: nell’ASLdi Brescia durante i mesi di gennaiomaggio 2003 si è verificato un consistente aumento di casi di meningite che ha allarmato oltre agli operatori sanitari anche l’opinione pubblica locale.

    Metodi: i dati riguardanti i casi di meningite verificatisi dal gennaio 1999 al maggio 2003 sono stati raccolti dal Servizio Igiene Pubblica dell’ASLdi Brescia.

    Tenuto conto della omogeneità dei dati nel quadriennio 1999- 2002 e della stagionalità che le meningiti possono avere, sono stati calcolati i tassi di incidenza per i primi cinque mesi dell’anno per tutte le meningiti in generale e per agente eziologico, durante il quadriennio 1999-2002. Tali tassi sono stati confrontati con i tassi corrispondenti nei primi mesi del 2003.

    Risultati: nel primi 5 mesi del 2003 si sono registrati in tutto 48 casi, di cui 9 da meningocco, 13 da pneumococco, 14 virali, 3 da altri agenti batterici e 8 senza agente microbico identificato. Nei 4 anni precedenti erano stati notificati 66 casi di meningite nei primi 5 mesi dell’anno, con una media annua di 16.5. Il tasso di incidenza di meningite in gennaio-maggio è stato quindi il triplo nel 2003 (rischio relativo = 2.9 rispetto ai 4 anni precedenti (p=0.0001. L’eccesso di incidenza si è riscontrato per tutti i tipi di meningite considerati in base all’agente eziologico.

    L’analisi per diverse età ha mostrato un aumento di incidenza sia nei bambini che nei giovani adulti e negli anziani. Non si è riscontrata alcuna differenza statisticamente significativa tra l’incidenza nel comune di Brescia (area urbana rispetto all’intera ASL nel periodo in studio.

    Conclusioni: l’aumento di incidenza per meningiti
    osservato nel 2003 non sembra spiegabile in termini di variabilità casuale del fenomeno da un anno all’altro e riguarda tutti i tipi di meningite e tutte le categorie d

  7. Talking to Your Doctor

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    Full Text Available ... NIH Website NIH Employee Intranet Staff Directory En Español Site Menu Home Health Information Health Info Lines ... Talking With Your Doctor , NIH News in Health Español Talking to Your Doctor , National Eye Institute (NEI) ...

  8. About the Eye

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    Full Text Available ... and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision ... DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home >> NEI for Kids >> ...

  9. Fra tradizione e sperimentazione: tecniche narrative nei racconti di ...

    African Journals Online (AJOL)

    Fra tradizione e sperimentazione: tecniche narrative nei racconti di Paola Capriolo. R Wilson, V Gerrand. Abstract. Contemporary novelists have responded in different ways to the challenge of living and writing in the latter half of the twentieth century, a historical moment in which the paper and ink with which they have ...

  10. About the Eye

    Medline Plus

    Full Text Available ... Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website ...

  11. About the Eye

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    Full Text Available ... and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision ... DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home » NEI for Kids » ...

  12. The Aging Eye

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  13. Diabetic Eye Disease

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  14. Eye Disease Simulations

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  15. About the Eye

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  16. About the Eye

    Medline Plus

    Full Text Available ... Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website ...

  17. About the Eye

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    Full Text Available ... Program Vision and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home >> NEI for Kids >> ...

  18. About the Eye

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    Full Text Available ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  19. About the Eye

    Medline Plus

    Full Text Available ... Program Vision and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit HHS USAJobs Home » NEI for Kids » ...

  20. Review on the NEI Methodology of Debris Transport Analysis in Sump Blockage Issue for APR1400

    International Nuclear Information System (INIS)

    Kim, Jong Uk; Lee, Jeong Ik; Hong, Soon Joon; Lee, Byung Chul; Bang, Young Seok

    2007-01-01

    Since USNRC (United State Nuclear Regulatory Committee) initially addressed post-accident sump performance under Unresolved Safety Issue USI A-43, sump blockage issue has gone through GSI-191, Regulation Guide 1.82, Rev. 3 (RG. 1.82 Rev.3), and generic Letter 2004-02 for PWRs (Pressurized Water Reactors). As a response of these USNRC's activities, NEI 04-07 was issued in order to evaluate the post-accident performance of a plant's recirculation sump. The baseline methodology of NEI 04-07 is composed of break selection, debris generation, latent debris, debris transport, and head loss. In analytical refinement of NEI 04-07, computational fluid dynamic (CFD) is suggested for the evaluation of debris transport in emergency core cooling (ECC) recirculation mode as guided by RG. 1.82 Rev.3. In Korea nuclear industry also keeps step with international activities of this safety issue, with Kori 1 plant as a pioneering edge. Korean nuclear industry has been also pursuing development of an advanced PWR of APR1400, which incorporates several improved safety features. One of the key features, considering sump blockage issue, is the adoption of IRWST (In-containment Refueling Water Storage Tank). This device, as the acronym implies, changes the emergency core cooling water injection pattern. This fact makes us to review the applicability of NEI 04-07's methodology. In this paper we discuss the applicability of NEI 04- 07's methodology, and more over, new methodology is proposed. And finally the preliminary debris transport is analyzed

  1. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Education Programs National Eye Health Education Program (NEHEP) Diabetic Eye Disease Education Program Glaucoma Education Program Low ... Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye Exam Dry Eye For ...

  2. Effects of thyroid status on NEI concentration in specific brain areas related to reproduction during the estrous cycle.

    Science.gov (United States)

    Ayala, Carolina; Pennacchio, Gisela Erika; Soaje, Marta; Carreño, Norma Beatriz; Bittencourt, Jakson Cioni; Jahn, Graciela Alma; Celis, María Ester; Valdez, Susana Ruth

    2013-11-01

    We previously showed that short-term hypo- and hyperthyroidism induce changes in neuropeptide glutamic-acid-isoleucine-amide (NEI) concentrations in discrete brain areas in male rats. To investigate the possible effects of hypo- and hyperthyroidism on NEI concentrations mainly in hypothalamic areas related to reproduction and behavior, female rats were sacrificed at different days of the estrous cycle. Circulating luteinizing hormone (LH), estradiol and progesterone concentrations were measured in control, hypothyroid (hypoT, treated with PTU during 7-9 days) and hyperthyroid (hyperT, l-T4 during 4-7 days) animals. Both treatments blunted the LH surge. Hypo- and hyperthyroidism increased estradiol concentrations during proestrus afternoon (P-PM), although hypoT rats showed lower values compared to control during proestrus morning (P-AM). Progesterone levels were higher in all groups at P-PM and in the hyperT during diestrus morning (D2). NEI concentrations were lower in hypoT rats during the estrous cycle except in estrus (E) in the peduncular part of the lateral hypothalamus (PLH). They were also reduced by both treatments in the perifornical part of the lateral hypothalamus (PeFLH) during P-PM. Hypothyroidism led to higher NEI concentrations during P-PM in the organum vasculosum of the lamina terminalis and anteroventral periventricular nucleus (OVLT+AVPV). The present results indicate that NEI concentration is regulated in a complex manner by hypo- and hyperthyroidism in the different areas studied, suggesting a correlation between NEI values and the variations of gonadal steroid levels during estrous cycle. These changes could be, in part, responsible for the alterations observed in the hypothalamic-pituitary-gonadal axis in these pathologies. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. 76 FR 28192 - Petition for Rulemaking Submitted by the Nuclear Energy Institute

    Science.gov (United States)

    2011-05-16

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 26 [Docket No. PRM-26-5; NRC-2010-0304] Petition for Rulemaking Submitted by the Nuclear Energy Institute AGENCY: Nuclear Regulatory Commission. ACTION: Petition... Anthony R. Pietrangelo, on behalf of the Nuclear Energy Institute (NEI), the petitioner, in the planned...

  4. Sports and Your Eyes

    Science.gov (United States)

    ... Hockey Paintball Racquetball Softball Squash Fencing Lacrosse Wrestling Football Golf Badminton Soccer Tennis Fishing Bicycling Gymnastics Track ... Media Policies and Other Important Links NEI Employee Emergency Information NEI Intranet (Employees Only) *PDF files require ...

  5. About the Eye

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    Full Text Available ... on Social Media Information in Spanish (Información en español) Website, Social Media Policies and Other Important Links NEI Employee Emergency Information NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the ...

  6. DFID-IDRC Program in Support of the African Institute for ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    ... for AIMS-NEI to offer enhanced training in applied mathematics to top African students, ... The ultimate objective is to create future leaders who will contribute to the ... The African Institute for Mathematical Sciences - Next Einstein Initiative ...

  7. Integrated model of primary and secondary eye care for underserved rural areas: The L V Prasad Eye Institute experience

    Directory of Open Access Journals (Sweden)

    Gullapalli N Rao

    2012-01-01

    Full Text Available Blindness is a major global public health problem and recent estimates from World Health Organization (WHO showed that in India there were 62 million visually impaired, of whom 8 million are blind. The Andhra Pradesh Eye Disease Study (APEDS provided a comprehensive estimate for prevalence and causes of blindness for the state of Andhra Pradesh (AP. It also highlighted that uptake of services was also an issue, predominantly among lower socio-economic groups, women, and rural populations. On the basis of this analysis, L V Prasad Eye Institute (LVPEI developed a pyramidal model of eye care delivery. This article describes the LVPEI eye care delivery model. The article discusses infrastructure development, human resource development, and service delivery (including prevention and promotion in the context of primary and secondary care service delivery in rural areas. The article also alludes to opportunities for research at these levels of service delivery and the amenability of the evidence generated at these levels of the LVPEI eye health pyramid for advocacy and policy planning. In addition, management issues related to the sustainability of service delivery in rural areas are discussed. The article highlights the key factors required for the success of the LVPEI rural service delivery model and discusses challenges that need to be overcome to replicate the model. The article concludes by noting the potential to convert these challenges into opportunities by integrating certain aspects of the existing healthcare system into the model. Examples include screening of diabetes and diabetic retinopathy in order to promote higher community participation. The results of such integration can serve as evidence for advocacy and policy.

  8. Diagram of the Eye

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  9. Facts About Pink Eye

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  10. National Emissions Inventory (NEI) 2011 Point Facility Data for the US (US EPA)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This map service displays 2011 USEPA National Emissions Inventory (NEI) point facility information for the United States. The map service was created for inclusion...

  11. National Emissions Inventory (NEI) 2005 Point Facility Data for the US (US EPA)

    Data.gov (United States)

    U.S. Environmental Protection Agency — This map service displays 2005 USEPA National Emissions Inventory (NEI) point facility information for the United States. The map service was created for inclusion...

  12. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity ...

  13. The Visual System

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us Visiting the NIH Campus Mission Statement As part ...

  14. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us Visiting the NIH Campus Mission Statement As part ...

  15. Glaucoma

    Medline Plus

    Full Text Available ... Accomplishments Budget and Congress About the NEI Director History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to the NEI Contact Us Visiting the NIH Campus Mission Statement As part ...

  16. NEI You Tube Videos: Amblyopia

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    Full Text Available ... Education Program (NEHEP) Diabetic Eye Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino ... Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision ...

  17. Evoluzione dell' abitudine al fumo nei locali dellíAzienda Ospedaliera Universitaria Senese dal 1998 al 2003

    Directory of Open Access Journals (Sweden)

    B. Bianconi

    2003-05-01

    Full Text Available

    Obiettivi: l’ospedale dovrebbe rappresentare un modello per la promozione della salute, tuttavia, nonostante i divieti di legge, l’abitudine di fumare in ospedale è ancora diffusa. Obiettivo dello studio è rilevare l’abitudine al fumo di personale sanitario, pazienti e visitatori, nei locali dell’AOUS.

    Metodi: alcuni studenti universitari, durante le loro attività curricolari, hanno percorso i locali del policlinico in orari diversi, contando il numero di persone incontrate, operatori sanitari e pazienti/visitatori, e indicando il numero di coloro che stavano fumando, in entrambe le categorie. Questo studio è stato ripetuto negli anni 1998, 1999 e 2003.

    Risultati: la prevalenza di persone che stavano fumando è risultata del 6,4% nel 1998, del 3,8% nel 1999 e dell’1,1% nel 2003. La prevalenza di operatori sanitari che fumavano rispetto al totale dei fumatori è risultata rispettivamente del 25%, del 26% e del 23,8%. Nei due anni passati, nell’atrio, nel bar e nelle zone antistanti i reparti c’era una maggiore presenza di persone che fumavano; mentre nell’ultima indagine sono stati riscontrati più fumatori, oltre che nell’atrio, nei corridoi del piano didattico, zona non indagata in precedenza. Nell’ultima rilevazione, non sono stati individuati fumatori nei due bar del policlinico; mentre sono sempre stati rilevati, in numero esiguo, operatori sanitari che fumano all’interno delle corsie di degenza.

    Conclusioni: la diminuzione costante del numero di fumatori in ospedale, mostra come ci sia stato negli ultimi anni un rispetto sempre maggiore del divieto di fumo nei luoghi di cura. Il coinvolgimento di futuri medici permette di promuovere il problema fumo in ospedale.

  18. Vision Related Quality of Life in Patients with Keratoconus

    Directory of Open Access Journals (Sweden)

    Sevda Aydin Kurna

    2014-01-01

    Full Text Available Purpose. The purpose of this study is to evaluate the vision related quality of life in patients with keratoconus by using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25. Methods. Thirty patients presented with keratoconus (keratoconus group and 30 healthy patients (control group were included in this study. Twenty patients were using rigid gas permeable and 10 patients were not using contact lenses in keratoconus group. High and low contrast visual acuity and mean K values of the patients were recorded. Each subject completed the 25-item NEI-VFQ-25. Results. All subscales of NEI-VFQ-25 were lower in the keratoconus patients. The difference was more evident in the subscales of general vision, ocular pain, near vision, vision-specific mental health, vision-specific role difficulties, and peripheral vision P 0.4 in the better eye had lower distance vision, social functioning, mental health, and role difficulties. Meanwhile, patients with low visual acuity (logMAR > 0.4 in the worse eye had lower general health scores P<0.05. Conclusions. Vision related quality of life was worse in keratoconus patients. Success in the contact lens usage and maintaining higher visual acuity may improve vision related quality of life.

  19. Principles of diet therapy in ancient Chinese medicine: 'Huang Di Nei Jing'.

    Science.gov (United States)

    Ho, Z C

    1993-06-01

    Huang Di Nei Jing, the first systematic Chinese medical book, was compiled from the observations of imperial herbal doctors in the Qin and Han periods (221 BC - 220 AD). From this classic traditional source may be derived the concept of a balanced and complete diet and probably the world's first dietary guidelines. Basic to the tradition are han, re, wen and bu foods, respectively 'cold', 'hot', 'neutral', 'strengthening'. Basic to Chinese cuisine are jan and tsai- 'cereal' (the rice staple and main meal) and 'dishes' to accompany the rice. Chinese traditional medicine, as in Huang Di Nei Jing, considers the nourishment of body and mind. It also emphasises that herbal medicine and food have the same origin. Diet was essential to the prevention of disease which a glossary of Chinese terms is given at the end of the paper in the Chinese tradition, was superior to treatment.

  20. Petrografía del neis de bucaramanga en cercanías a cepitá, berlín y vetas – santander.

    OpenAIRE

    Urueña Suarez, Cindy Lizeth; Zuluaga Castrillon, Carlos Augusto

    2011-01-01

    El Neis de Bucaramanga es la unidad litodémica más antigua del basamento ígneo-metamórfico del Macizo de Santander, las tres grandes fajas (occidental o faja Bucaramanga, central y oriental) que han sido descritas comprenden una sucesión de neises pelíticos y semipelíticos intercalados con capas delgadas de rocas calcosilicatadas, mármoles, neis hornbléndico y anfibolita. El neis fue estudiado en un área que abarca los alrededores de Cepitá, Bucaramanga, Vetas y el páramo de Berlín con el fin...

  1. The history of keratoprosthetics in the S. Fyodorov Eye Microsurgery Federal State Institution

    OpenAIRE

    Z.I. Moroz; V.A. Vlasova; E.V. Kovshun

    2013-01-01

    ABSTRACT The article highlights a 45-year experience in keratoprosthetics at the S. Fyodorov Eye Microsurgery Federal State Institution. During this period, more than 1,000 keratoprostheses of different types has been implanted. The design features, advantages and disadvantages of foreign keratoprosthesis – Choyce-1, Choyce-2, H. Cardona «bolt-nut», which were used in the clinic in the first stages of prosthetics of the cornea, are described. There are presented the...

  2. Changes in Quality of Life in Visually Impaired Patients after Low-Vision Rehabilitation

    Science.gov (United States)

    Renieri, Giulia; Pitz, Susanne; Pfeiffer, Norbert; Beutel, Manfred E.; Zwerenz, Rudiger

    2013-01-01

    The objective of the study was to assess the impact of low-vision aids on quality of life. Interviews included a modified version of the National Eye Institute Visual Functioning Questionnaire (Modified German NEI VFQ-25), the Hospital Anxiety and Depression Scale, the Mini-Mental State Examination Blind, and Indicators of the Rehabilitation…

  3. Psychometric properties of the national eye institute refractive error correction quality-of-life questionnaire among Iranian patients

    Directory of Open Access Journals (Sweden)

    Amir H Pakpour

    2013-01-01

    Conclusions: The Iranian version of the NEI-RQL-42 is a valid and reliable instrument to assess refractive error correction quality-of-life in Iranian patients. Moreover this questionnaire can be used to evaluate the effectiveness of interventions in patients with refractive errors.

  4. Il diritto alla salute dei migranti nei Paesi Bassi

    OpenAIRE

    Romeo, Graziella; Palazzo, Nausica

    2017-01-01

    L’articolo affronta il tema del diritto alla salute del migrante nei Paesi Bassi. Nel far ciò si propone innanzitutto di fornire un inquadramento riguardante la condizione dello straniero dal punto di vista lato sensu costituzionale, e le politiche di assimilazione dello straniero poste in essere dal governo in anni recenti. L’articolo intende in seguito di ricostruire le peculiarità del sistema sanitario olandese e le tipologie di migranti riconosciute a livello domestico, al fine di incroc...

  5. 75 FR 10444 - Nuclear Energy Institute; Denial of Petition for Rulemaking

    Science.gov (United States)

    2010-03-08

    ... NUCLEAR REGULATORY COMMISSION 10 CFR Part 73 [Docket No. PRM-73-14; NRC-2009-0493] Nuclear Energy... (PRM) submitted by the Nuclear Energy Institute (NEI) (the petitioner). The petitioner requested that... rulemaking. The petitioner states that the nuclear energy industry has fully implemented numerous new...

  6. Dwarf Eye Disorder

    Science.gov (United States)

    Science Teacher, 2005

    2005-01-01

    Johns Hopkins researchers at the Wilmer Eye Institute have discovered what appears to be the first human gene mutation that causes extreme farsightedness. The researchers report that nanophthalmos, Greek for "dwarf eye," is a rare, potentially blinding disorder caused by an alteration in a gene called MFRP that helps control eye growth and…

  7. Eye Injuries at Work

    Science.gov (United States)

    ... National Standards Institute (ANSI) to meet their eye protection standards. If an eye injury occurs, see an ophthalmologist or go to the emergency room immediately, even if the eye injury appears minor. Delaying medical attention can result in permanent vision ...

  8. The Visual System

    Medline Plus

    Full Text Available ... Fun Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables The Visual System Ever wonder how your eyes work? Watch this ... Policies and Other Important Links NEI Employee Emergency Information NEI ... | USA.gov NIH…Turning Discovery Into Health ®

  9. The Visual System

    Medline Plus

    Full Text Available ... History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  10. Glaucoma

    Medline Plus

    Full Text Available ... History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  11. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... History of the NEI NEI 50th Anniversary NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  12. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, ...

  13. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Vision Education Program Hispanic/Latino Program Vision and Aging Program African American Program Training and Jobs Fellowships ... Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive ...

  14. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... NIH), the National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of ...

  15. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... Clinical Director Laboratories, Sections and Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office ... Diabetic Eye Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino Program Vision and ...

  16. Determination of Risk Factors and Treatment of Dry Eye Disease in Type 1 Diabetes Before Corneal Complications at Sindh Institute of Ophthalmology And Visual Sciences.

    Science.gov (United States)

    Shujaat, Shehnilla; Jawed, Muhammad; Memon, Shahzad; Talpur, Khalid Iqbal

    2017-01-01

    The objective of this study was to assess and determine the risk factors and treatment of dry eye disease in type 1 diabetes before any ocular surface or corneal complication occurs. This study was conducted at Sindh Institute of Ophthalmology And Visual Sciences, Hyderabad, Pakistan. Subjects and methods for observational study were undertaken at the Department of Ophthalmology Sindh Institute Of Ophthalmology And Visual Sciences, Hyderabad, Pakistan. Hundred confirmed cases of type 1 diabetes were included in the study by non probability convenience sampling. Tear film breakup time and schrimer test were carried out to determine dry eye disease. Data was collected by self-prepared questionnaire and entered and analyzed by using Statistical Program for Social Sciences (SPSS, version 20.0). The frequencies and percentage were recorded and any associations with predisposing factors were statistically analyzed by t test. Out of hundred patients, 71 (71%) were found to have dry eyes (Pdry eye disease (Pdry eyes in males and females. Long duration was found to be related with increased occurrence of dry eyes (Pdry eyes. There is marked increase in frequency/ risk of developing dry eye disease in type 1 diabetes patients. Therefore, it is recommended to have periodic ophthalmic examination for type 1 diabetic patients.

  17. What Is a Comprehensive Dilated Eye Exam?

    Science.gov (United States)

    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  18. [A Study on the quotations in the Wu xing da yi (The Gist of Five Phases) cited from Nei jing (Inner Canon)].

    Science.gov (United States)

    Wang, Zheng-Shan; Zhang, Qi-Cheng

    2013-07-01

    In the Wu xing da yi (The Gist of Five Phases), written by Xiao Ji of the Sui Dynasty, there were 9 quotations cited from Huang di nei jing (Inner Canon of Huangdi). By comparison with current version of Huang di nei jing, most of the descriptions are similar, yet still with some differences, such as yin-yang nature of the five zang visceras, the liver being the root of "pi ji", the spleen being the root of "cang lin" etc. Wu xing da yi epitomizes the books about yin-yang and five phases before the Sui Dynasty, while Xiao Ji's quotations from Huang di nei jing interpreted from the views of yin-yang and five phases, are different from the annotations of later ages.

  19. Surgical removal of eyes in a tertiary institution in North eastern ...

    African Journals Online (AJOL)

    Background Surgical eye removal is performed for various end-stage eye diseases to provide adequate comfort, replace volume and give good functional and cosmetic appearance. The pattern of eye removal is unknown for North Eastern Nigeria. Objective To determine the indications for eye removal in the study ...

  20. The King-Devick (K-D) test of rapid eye movements: a bedside correlate of disability and quality of life in MS.

    Science.gov (United States)

    Moster, Stephen; Wilson, James A; Galetta, Steven L; Balcer, Laura J

    2014-08-15

    We investigated the King-Devick (K-D) test of rapid number naming as a visual performance measure in a cohort of patients with multiple sclerosis (MS). In this cross-sectional study, 81 patients with MS and 20 disease-free controls from an ongoing study of visual outcomes underwent K-D testing. A test of rapid number naming, K-D requires saccadic eye movements as well as intact vision, attention and concentration. To perform the K-D test, participants are asked to read numbers aloud as quickly as possible from three test cards; the sum of the three test card times in seconds constitutes the summary score. High-contrast visual acuity (VA), low-contrast letter acuity (1.25% and 2.5% levels), retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT), MS Functional Composite (MSFC) and vision-specific quality of life (QOL) measures (25-Item NEI Visual Functioning Questionnaire [NEI-VFQ-25] and 10-Item Neuro-Ophthalmic Supplement) were also assessed. K-D time scores in the MS cohort (total time to read the three test cards) were significantly higher (worse) compared to those for disease-free controls (P=0.003, linear regression, accounting for age). Within the MS cohort, higher K-D scores were associated with worse scores for the NEI-VFQ-25 composite (Paccounting for age and within-patient, inter-eye correlations). Patients with a history of optic neuritis (ON) had increased (worse) K-D scores. Patients who classified their work disability status as disabled (receiving disability pension) did worse on K-D testing compared to those working full-time (P=0.001, accounting for age). The K-D test, a work disability as well as structural changes as measured by OCT imaging. History of ON and abnormal binocular acuities were associated with worse K-D scores, suggesting that abnormalities detected by K-D may go along with afferent dysfunction in MS patients. A brief test that requires saccadic eye movements, K-D should be considered for future MS trials as

  1. About the Eye

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  2. Cataract Surgery Visual Outcomes and Associated Risk Factors in Secondary Level Eye Care Centers of L V Prasad Eye Institute, India.

    Directory of Open Access Journals (Sweden)

    Sumathi Matta

    Full Text Available To evaluate cataract surgery visual outcomes and associated risk factors in rural secondary level eye care centers of L V Prasad Eye Institute (LVPEI, India.The Eye Health pyramid of LVPEI has a network of rural secondary care centres (SCs and attached vision centres (VCs that provide high quality comprehensive eye care with permanent infrastructure to the most disadvantaged sections of society. The most common procedure performed at SCs is cataract surgery. We audited the outcome of a random sample of 2,049 cataract surgeries done from October 2009-March 2010 at eight rural SCs. All patients received a comprehensive ophthalmic examination, both before and after surgery. The World Health Organization recommended cataract surgical record was used for data entry. Visual outcomes were measured at discharge, 1-3 weeks and 4-11 weeks follow up visits. Poor outcome was defined as best corrected visual acuity <6/18.Mean age was 61.8 years (SD: 8.9 years and 1,133 (55.3% surgeries were performed on female patients. Pre-existing ocular co-morbidity was present in 165 patients (8.1%. The most common procedure was small incision cataract surgery (SICS with intraocular lens (IOL implantation (91.8%. Intraoperative complications were seen in 29 eyes (1.4%. At the 4-11 weeks follow-up visit, based on presenting visual acuity (PVA, 61.8% had a good outcome and based on best-corrected visual acuity (BCVA, 91.7% had a good outcome. Based on PVA and BCVA, those with less than 6/60 were only 2.9% and 1.6% respectively. Using multivariable analysis, poor visual outcomes were significantly higher in patients aged ≥70 (OR 4.63; 95% CI 1.61, 13.30, in females (OR 1.58; 95% CI 1.04, 2.41, those with preoperative comorbidities (odds ratio 4.68; 95% CI 2.90, 7.57, with intraoperative complications (OR 8.01; 95% CI 2.91, 22.04, eyes that underwent no IOL or anterior chamber-IOL (OR 12.63; 95% CI 2.65, 60.25 and those undergoing extracapsular cataract extraction (OR 9

  3. Biochemical Characterization of Mycobacterium tuberculosis DNA Repair Enzymes – Nfo, XthA and Nei2

    Directory of Open Access Journals (Sweden)

    Sailau Abeldenov

    2014-01-01

    Full Text Available Introduction: Tuberculosis (TB is a human disease caused by Mycobacterium tuberculosis (Mtb. Treatment of TB requires long-term courses of multi-drug therapies to eliminate subpopulations of bacteria, which sometimes persist against antibiotics. Therefore, understanding of the mechanism of Mtb antibiotic-resistance is extremely important. During infection, Mtb overcomes a variety of body defense mechanisms, including treatment with the reactive species of oxygen and nitrogen. The bases in DNA molecule are susceptible to the damages caused by reactive forms of intermediate compounds of oxygen and nitrogen. Most of this damage is repaired by the base excision repair (BER pathway. In this study, we aimed to biochemically characterize three Mtb DNA repair enzymes of BER pathway. Methods: XthA, nfo, and nei genes were identified in mycobacteria by homology search of genomic sequences available in the GenBank database. We used standard methods of genetic engineering  to clone and sequence Mtb genes, which coded Nfo, XthA and Nei2 repair enzymes. The protein products of Mtb genes were expressed and purified in Escherichia coli using affinity tags. The enzymatic activity of purified Nfo, XthA, and Nei2 proteins were measured using radioactively labeled DNA substrates containing various modified residues. Results: The genes end (Rv0670, xthA (Rv0427c, and nei (Rv3297 were PCR amplified using genomic DNA of Mtb H37Rv with primers that contain specific restriction sites. The amplified products were inserted into pET28c(+ expression vector in such a way that the recombinant proteins contain C-terminal histidine tags. The plasmid constructs were verified by sequencing and then transformed into the Escherichia coli BL21 (DE3 strain. Purification of recombinant proteins was performed using Ni2+ ions immobilized affinity column, coupled with the fast performance liquid chromatography machine AKTA. Identification of the isolated proteins was performed by

  4. About the Eye

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  5. About the Eye

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    Full Text Available ... Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino Program ... To search for current job openings visit HHS USAJobs Home » NEI for ...

  6. Quality of life and visual acuity outcomes in the Registry in Glaucoma Outcomes Research study.

    Science.gov (United States)

    Coleman, Anne L; Lum, Flora C; Gliklich, Richard E; Velentgas, Priscilla; Su, Zhaohui

    2016-01-01

    The RiGOR study evaluated the association of treatment and patient-reported outcomes for open-angle glaucoma patients. The Glaucoma Symptom Scale (National Eye Institute-Visual Function Questionnaire (NEI-VFQ) and visual acuity (VA) were collected as quality of life measures. The proportion of patients with improvement of at least two lines of vision was highest in the incisional surgery group (14.2% compared with 9.9% for laser surgery and 10.9% for additional medication). No clinically relevant differences were seen in benefit for the laser surgery or incisional surgery groups compared with additional medications for the Glaucoma Symptom Scale or NEI-VFQ measures or subscales. Differences in quality of life by race need to be explored in further studies.

  7. Ask a Scientist: What is Color Blindness?

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  8. The Visual System

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    Full Text Available ... the NEI Website search NEI on Social Media | Search A-Z | en español | Text size S M L ... (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ...

  9. About the Eye

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    Full Text Available ... News from NEI Grantees Spokesperson bios Statistics and Data Resources for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media ...

  10. About the Eye

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  11. Fish eye optics

    Czech Academy of Sciences Publication Activity Database

    Hudec, René; Michalová, S.

    2017-01-01

    Roč. 47, č. 2 (2017), s. 94-99 ISSN 1335-1842. [INTEGRAL/BART Workshop /14./. Karlovy Vary, 03.04.2017-07.04.2017] Grant - others:GA ČR(CZ) GA13-33324S Institutional support: RVO:67985815 Keywords : fish eye optics * lobster eye optics * X-ray monitoring Subject RIV: BN - Astronomy, Celestial Mechanics, Astrophysics OBOR OECD: Astronomy (including astrophysics,space science) Impact factor: 0.336, year: 2016

  12. Ask a Scientist: What is Color Blindness?

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  13. The Visual System

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  14. Impact of strabismus on the quality of life of Chinese Han teenagers

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    Tu CS

    2016-06-01

    Full Text Available Changsen Tu, Liang Ye, Longfei Jiang, Yuwen Wang, Yingzi Li The Eye Hospital of Wenzhou Medical University, School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, People’s Republic of China Background: Although much research has been conducted on the impact of strabismus on the quality of life (QoL of adults, the effect of this condition on teenagers has not been extensively studied. This study therefore aimed to assess the effect of strabismus on the vision-related QoL of Chinese teenagers.Methods: The Chinese version of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25 was self-administered by 1,040 teenagers with strabismus and 1,002 individuals with normal vision. All the participants were from the Chinese Han population. The independent samples t-test was used to compare QoL between teenagers with and without strabismus.Results: The majority of scores on the NEI-VFQ-25 domains were significantly different between the two groups. QoL was significantly lower in individuals with strabismus compared with teenagers with normal vision on all domains, with the exception of social functioning.Conclusion: Statistically significantly lower vision-related QoL scores were found in Chinese Han teenagers with strabismus compared with those without strabismus. Keywords: quality of life, strabismus, NEI-VFQ-25, teenager, HRQoL

  15. About the Eye

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  16. Fluid Mixing in the Eye Under Rapid Eye Movement

    Science.gov (United States)

    Huang, Jinglin; Gharib, Morteza

    2017-11-01

    Drug injection is an important technique in certain treatments of eye diseases. The efficacy of chemical mixing plays an important role in determining pharmacokinetics of injected drugs. In this study, we build a device to study the chemical mixing behavior in a spherical structure. The mixing process is visualized and analyzed qualitatively. We hope to understand the chemical convection and diffusion behaviors in correlation with controlled rapid mechanical movements. The results will have potential applications in treatment of eye diseases. Resnick Institute at Caltech.

  17. Emanuele KANCEFF, "L’immagine della Sicilia nei resoconti di viaggio del Settecento. Tra classicità ed emozione romantica", 2015

    Directory of Open Access Journals (Sweden)

    Pino Menzio

    2015-06-01

    Full Text Available Emanuele KANCEFF, "L’immagine della Sicilia nei resoconti di viaggio del Settecento. Tra classicità ed emozione romantica", Scicli, Edizioni di storia e studi sociali, 2015 [Book Review

  18. Application of the NEI 95-10 methodology in the Rcic system of the Unit-1, to implement the criterions of the license renovation rule; (10 Cfr-54); Aplicacion de la metodologia del NEI 95-10 en el sistema RCIC de la U-1, para implementar los criterios de la regla de renovacion de licencia; (10 CFR54)

    Energy Technology Data Exchange (ETDEWEB)

    Diaz, A.; Mendoza, G.; Arganis, C.; Viais, J.; Contreras, A. [ININ, Carretera Mexico-Toluca s/n, 52750 Ocoyoacac, Estado de Mexico (Mexico); Fernandez, G.; Medina, G., E-mail: angeles.diaz@inin.gob.mx [Comision Federal de Electricidad, Central Nucleoelectrica Laguna Verde, Carretera Cardel-Nautla Km 42.5, Alto Lucero, Veracruz (Mexico)

    2012-10-15

    In December of 1991, the US National Regulatory Commission (US NRC) published the 10 Cfr-54, to establish the procedures, criterions and necessary requirements for the license renovation of a nuclear power station. In 1994 the US NRC proposed an amendment to these requirements that basically were centered in the effects of the aging in structures and passive components of long life and in the inclusion of Time Limited Aging Analyses (TLAAs). In a general way, is established that the requester should show to the regulator body that the effects of the aging in structures, systems and components are and will be appropriately negotiated or that the TLAAs has been evaluated for the operation extended period. The NEI 95-10 is a guide document developed by the Nuclear Energy Institute (NEI), to provide a focus accepted to cover the requirements of 10 Cfr-54, offering an efficient process that allows to any requester to complete in a practical way the requirements of the License Renovation Rule and to supplement their solicitude. This work presents the application of this guide to the Reactor Core Insulation Cooling (Rcic) of the Unit 1 of the nuclear power plant of Laguna Verde, elect as pilot system to carry out the application of the 10 Cfr-54 following the recommended methodology by the Industrial Guide for the implementation of the License Renovation Rule. (Author)

  19. About the Eye

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    Full Text Available ... Program Vision and Aging Program African American Program Training and Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit ...

  20. Indications and Visual Outcome of Penetrating Keratoplasty in Tertiary Eye Care Institute in Uttarakhand

    Science.gov (United States)

    Gupta, Neeti; Dhasmana, Renu; Nagpal, Ramesh Chander; Bahadur, Harsh; Maitreya, Amit

    2016-01-01

    Introduction Corneal blindness forms significant proportion of visual blindness in developing countries and penetrating keratoplasty (PK) can restore vision for this. The prognosis of PK is dependent on the corneal diseases responsible for corneal blindness. Aim To evaluate the indications and visual outcome of PK in tertiary eye care institute in Uttarakhand. Materials and Methods Data was reviewed from the medical records of 145 PK done in Department of Ophthalmology, Himalayan Institute of Medical Sciences from January 2012 to October 2014. Analysis of data was done for evaluation of the indications and visual outcome by Paired student’s t-test for hypothesis testing of grouped values of preoperative and last follow-up best corrected visual acuity in cases of optical and therapeutic grafts. A p-value < 0.05 was considered statistically significant. Results In this study data of 145 eyes of 138 patients was reviewed. The most common indication for keratoplasty was corneal scarring including adherent leucoma 48 (33.10%). Therapeutic keratoplasty was done for 33 cases with maximum 30(20.68%) cases of infectious keratitis. One case of tectonic graft was included in therapeutic keratoplasty group for analysis. There was statistically significant difference (p=.0001) in best corrected visual acuity improvement from 1.39 logMAR+ 0.022(SD) preoperatively to 0.367 logMAR+0.44(SD) postoperatively and 1.4 logMAR+.000(SD) preoperatively to 0.16 logMAR+0.57(SD) postoperatively for optical and therapeutic grafts respectively. Conclusion Infective keratitis either active or healed was the major indication for keratoplasty. Poor prognosis indications were most common in this part of the country. The visual outcome following corneal transplantation was encouraging particularly in cases of optical keratoplasty. PMID:27504319

  1. About the Eye

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    Full Text Available ... where your vision is sharpest. Optic nerve (OP-tic nurv) is the bundle of more than 1 ... NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  3. Polimorfismi nei geni metabolici come fattori dirischio per il carcinoma gastrico (GC: risultati preliminari di uno studio caso-controllo

    Directory of Open Access Journals (Sweden)

    S. Boccia

    2003-05-01

    Full Text Available

    Obiettivi: valutare le frequenze dei principali geni metabolici in un campione di casi di GC (Carcinoma Gastrico e di controlli, per determinare se esiste un’associazione con il rischio di GC, e considerare le possibili associazioni tra i genotipi studiati ed alcuni parametri clinico-patologici.

    Metodi: è stato condotto uno studio caso-controllo ospedaliero, tra novembre 1999 e maggio 2003 reclutando 48 pazienti con diagnosi di adenocarcinoma gastrico sottoposti a gastrectomia, e 48 controlli appaiati per sesso ed età presso il Policlinico Universitario “A. Gemelli” in Roma. Per genotipizzare gli individui rispetto ai geni GSTM1, NAT2, SULT1A1, CYP1A1, CYP2E1 (5’ flanking e introne 6, è stata usata la tecnica della PCR con analisi del profilo dei frammenti di restrizione (PCR-RFLP. L’analisi statistica ha previsto l’impiego di test non parametrici e della regressione logistica.

    Risultati: le frequenze dei polimorfismi nei geni metabolici sono risultate in alcuni casi differenti nei casi rispetto ai controlli sebbene non si evidenzi una differenza statisticamente significativa. In particolare il genotipo GSMT1 null è più elevato nei pazienti rispetto ai controlli (63.8% vs. 51% e gli individui NAT2 acetilatori lenti risultano più frequenti nei casi rispetto ai controlli (69.6% vs. 57.45%. L’istotipo diffuso di GC è associato significativamente ai pazienti eterozigoti per l’allele SULT1A1 (c_= 8.216; p= 0.018, ed i pazienti NAT2 acetilatori lenti tendono ad avere un grading tumorale alto (c_= 7.425; p= 0.006.

    Conclusioni: i risultati preliminari di questo studio evidenziano associazioni tra alcuni genotipi metabolici e parametri clinico-patologici, che se confermati potrebbero permettere di identificare sottogruppi con prognosi più sfavorevole di GC da indirizzare preventivamente verso trattamenti specifici.

  4. NEI You Tube Videos: Amblyopia

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    Full Text Available ... is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding ... NEI Office of Communications (301)496-5248 Health Information Frequently asked questions Clinical Studies Publications Catalog Photos ...

  7. About the Eye

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  8. NEI You Tube Videos: Amblyopia

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  9. About the Eye

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    Full Text Available ... Extramural Science Programs Division of Extramural Activities Extramural Contacts NEI Division of Extramural Research Suite 1300 5635 Fishers Lane, MSC ... Macula (MACK-yoo-luh) is the small, sensitive area of the retina needed for central vision. It ...

  10. About the Eye

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  11. About the Eye

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  12. About the Eye

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  13. Application of the NEI 95-10 methodology in the Rcic system of the Unit-1, to implement the criterions of the license renovation rule; (10 Cfr-54)

    International Nuclear Information System (INIS)

    Diaz, A.; Mendoza, G.; Arganis, C.; Viais, J.; Contreras, A.; Fernandez, G.; Medina, G.

    2012-10-01

    In December of 1991, the US National Regulatory Commission (US NRC) published the 10 Cfr-54, to establish the procedures, criterions and necessary requirements for the license renovation of a nuclear power station. In 1994 the US NRC proposed an amendment to these requirements that basically were centered in the effects of the aging in structures and passive components of long life and in the inclusion of Time Limited Aging Analyses (TLAAs). In a general way, is established that the requester should show to the regulator body that the effects of the aging in structures, systems and components are and will be appropriately negotiated or that the TLAAs has been evaluated for the operation extended period. The NEI 95-10 is a guide document developed by the Nuclear Energy Institute (NEI), to provide a focus accepted to cover the requirements of 10 Cfr-54, offering an efficient process that allows to any requester to complete in a practical way the requirements of the License Renovation Rule and to supplement their solicitude. This work presents the application of this guide to the Reactor Core Insulation Cooling (Rcic) of the Unit 1 of the nuclear power plant of Laguna Verde, elect as pilot system to carry out the application of the 10 Cfr-54 following the recommended methodology by the Industrial Guide for the implementation of the License Renovation Rule. (Author)

  14. L'espressione del passato nei quotidiani delle lungue balcaniche*

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    Momčilo D. Savić

    1974-12-01

    Full Text Available È inutile sottolineare che le lingue parlate dai popoli della Penisola balca­ nica vanno d'accordo in molti punti, pur non avendo la stessa origine. Le affinita in questione sono dovute tanto alla simbiosi quanto alia convivenza prolungatasi a un periodo plurisecolare. Però se non è sempre possibile de­ terminare i confini etnici di un popolo balcanico (cosa che trova riscontro anche altrove, non è neanche meno facile segnarne i rispettivi limiti linguistici. Senza dubbio, possi.amo supporre chela situazione in questo campo fosse molto piu complicata nei secoli scorSii, essendosi costituite le nazioni vere e proplie appena con le rivoluzioni borghesi, e specialmente se ricordiamo che in certe zone dei Balcani continuano ad essere applicate più lingue e che vi incontriamo oggi stesso un numero non insignificante di persone bilingui ovvero plurilingui.

  15. NEI You Tube Videos: Amblyopia

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  16. Eye Wear: MedlinePlus Health Topic

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    ... When You Exercise (National Institute on Aging) - PDF Topic Image MedlinePlus Email Updates Get Eye Wear updates by email What's this? GO Related Health Topics Refractive Errors National Institutes of Health The primary ...

  17. NEI You Tube Videos: Amblyopia

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    Full Text Available ... to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... Clinical Studies Publications Catalog Photos ...

  18. Glaucoma

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  19. What the Age-Related Eye Disease Studies Mean for You (AREDS2)

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  20. Prevalence of Adult Vision Impairment and Age-Related Eye Diseases in America

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  1. For Parents, Teachers and Coaches: About Sports Eye Injury and Protective Eyewear

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    ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed ...

  2. Emerging Technologies Look Deeper into the Eyes to Catch Signs of Disease

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  3. About the Eye

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  4. NEI You Tube Videos: Amblyopia

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  5. NEI You Tube Videos: Amblyopia

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  6. NEI You Tube Videos: Amblyopia

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    Full Text Available ... of visual function, preservation of sight, and the special health problems and requirements of the blind.” News & ... Emily Y. Chew, M.D., Deputy Clinical Director Education Programs National Eye Health Education Program (NEHEP) Diabetic ...

  7. Five years of proton therapy of tumours of the eye at Hahn-Meitner Institute, Berlin

    International Nuclear Information System (INIS)

    Heufelder, J.; Cordini, D.; Heese, J.; Homeyer, H.; Kluge, H.; Morgenstern, H.; Fuchs, H.; Hoecht, S.; Nausner, M.; Hinkelbein, W.; Bechrakis, N.E.; Foerster, M.H.

    2004-01-01

    Eye tumors (choroidal melanomas, iris melanomas, and choroidal hemangiomas) are being treated with 68 MeV protons since 1998 at the Ion Beam Laboratory of the Hahn-Meitner Institute of Berlin (Germany's first proton therapy center), in cooperation with the Charite University Hospital in Berlin, Campus Benjamin Franklin. The proton beam, generated via a combination of Van de Graaff accelerator and cyclotron, is prepared by passive shaping for conformal tumor irradiation. A digital X-ray verification of the tumor location with the patient in sitting position limits the position uncertainties to a maximum of 0,3 mm. The treatment planning is performed using the program EYEPLAN. OCTOPUS, a CT-based planning program developed in cooperation with the German Cancer Research Center of Heidelberg, is under pre-clinical testing. Thus far, more than 400 patients have been irradiated. The first results are comparable to those obtained in other proton therapy centers. At the end of 2002, the University Hospital of Essen has also become a cooperation partner of the Hahn-Meitner Institute. (orig.) [de

  8. NEI You Tube Videos: Amblyopia

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  9. NEI You Tube Videos: Amblyopia

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    Full Text Available ... Diabetic Eye Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino Program Vision and Aging ... Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos ...

  10. Absolute transition probabilities in the NeI 3p-3s fine structure by beam-gas-dye laser spectroscopy

    International Nuclear Information System (INIS)

    Hartmetz, P.; Schmoranzer, H.

    1983-01-01

    The beam-gas-dye laser two-step excitation technique is further developed and applied to the direct measurement of absolute atomic transition probabilities in the NeI 3p-3s fine-structure transition array with a maximum experimental error of 5%. (orig.)

  11. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. Miller, Ph.D., ... David M. Schneeweis, Ph.D., Deputy Scientific Director Office of the Clinical Director Brian P. Brooks, M. ...

  12. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of ... Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations ...

  13. NEI You Tube Videos: Amblyopia

    Medline Plus

    Full Text Available ... programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and ... Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media Relations ...

  14. Tempi che cambiano, luoghi che si trasformano: i mutamenti nei nuraghi fra l’età del Bronzo ed il Primo Ferro

    Directory of Open Access Journals (Sweden)

    Mauro Perra

    2017-01-01

    Full Text Available Riassunto: Il lungo percorso della Civiltà Nuragica, compreso fra XVII e X-IX secolo a.C., si caratterizza come un’epoca di grandi trasformazioni che si susseguono nel tempo e lasciano visibili tracce in un paesaggio mutevole, come in un succedersi di macroscopiche unità stratigrafiche. Si trasformano profondamente così non solo i monumenti ed il paesaggio, ma anche le stesse strutture sociali e politiche delle comunità nuragiche fino alla trasfigurazione del ricordo in mito nei centri cerimoniali o santuari. Abstract: The long trajectory of the Nuragic civilisation (17th - 10th/9th centuries B.C. is characterised by a succession of dramatic changes leaving visible traces in a varying landscape, like stratigraphy on a regional scale. These changes affect not only the Nuragic monuments and landscape but also the social and political institutions of Nuragic communities, culminating in a transfiguration of memory and a new mythology apparent in ceremonial centres and sanctuaries.

  15. Eye and orbit ultrasound

    Science.gov (United States)

    ... Images Head and eye echoencephalogram References Coleman DJ, Silverman RH, Lloyd HO, Daly S. Evaluation of the posterior ... Vision Institute, La Jolla, CA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial ...

  16. EDITORIAL: Special issue containing contributions from the Sixth Biennial Research Congress of The Eye and the Chip Special issue containing contributions from the Sixth Biennial Research Congress of The Eye and the Chip

    Science.gov (United States)

    Hessburg, Philip C.

    2011-06-01

    same spirit.' A letter to us from our co-organizer of The Eye and the Chip, Joseph Rizzo MD, Harvard Medical School, furthers the point that the Research Congress Model is productive. This model is based on a belief that collegiality enhances collaboration and that collaboration accelerates progress. 'At the time of our first The Eye and the Chip meeting, now many years ago, the field of visual prosthetics was still in its infancy. The research community generally held a very skeptical attitude about the possible use of a bio-electronic implant to restore vision, despite the great success of cochlear implants. Over the last two decades our field has matured dramatically, and now there is widespread optimism about the potential for visual implants to help patients who are blind. 'The marked improvement in our status as a field is the result of excellent research from a large critical mass of scientists from throughout the world. It is the general opinion of researchers in our field that The Eye and the Chip meeting has provided the most vibrant source of scientific exchange for our field. The reasons for the success of this meeting relate to the fact that the meeting is devoted to a single topic, it is all-inclusive (anyone who is performing credible research in the field is invited to participate) and it provides a very substantial amount of time for open group discussions. These attributes expand the length of the meeting, which I understand increases the cost of the meeting, but the benefits have been remarkable for our field. Simply stated, The Eye and the Chip meeting provides the best venue for scientific and academic exchange in the world for the field of visual prosthetics.' And, furthermore, following a rather spirited discussion on the end points to be used in evaluating these devices on the third and final day of The Eye and the Chip last September, the Food and Drug Administration (FDA), under the leadership of the US National Eye Institute (NEI), held a

  17. Glaucoma

    Medline Plus

    Full Text Available ... Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye Exam Dry Eye For Kids Glaucoma Healthy Vision Tips Leber Congenital Amaurosis Low Vision Refractive Errors Retinopathy of Prematurity Science Spanish Videos Webinars NEI YouTube ...

  18. Human eye localization using the modified Hough transform

    Czech Academy of Sciences Publication Activity Database

    Dobeš, M.; Martínek, J.; Skoupil, D.; Dobešová, Z.; Pospíšil, Jaroslav

    2006-01-01

    Roč. 117, - (2006), s. 468-473 ISSN 0030-4026 Institutional research plan: CEZ:AV0Z10100522 Keywords : human eye localization * modified Hough transform * eye iris and eyelid shape determination Subject RIV: BH - Optics, Masers, Lasers Impact factor: 0.585, year: 2006

  19. [Quality of life in patients with age-related macular degeneration - medical and social problem].

    Science.gov (United States)

    Muzyka-Woźniak, Maria; Misiuk-Hojło, Marta; Wesolowska, Alicja

    2011-01-01

    Age-related macular degeneration (AMD) is a leading cause of blindness over the age of 50 in western countries. People with AMD are suffering from serious vision-related disability and their social life is compromised. The aim of our study was to assess quality of life (QoL) in patients with exudative AMD. The study group was 100 patients treated for AMD, the control group were 30 age and sex matched subjects without ophthalmic disorders. Patients were treated with anti-VEGF therapy, by means of National Eye Institute Visual Function Questionnaire (NEI VFQ-25). As well as visual function, the NEI-VFQ investigates social functioning, mental health and dependency. There was statistically significant difference in QoL overall score between study group and control group. Patients with AMD obtained 51.1 (+/- 20.5 ) overall score, control group reached 83.7 (+/- 11.7) overall score, p = 0.001. Detailed analysis of study group revealed low acceptance of the disease and strong dependency. QoL in patients with AMD assessed with NEI VFQ-25, is significantly impaired. Low quality of life and difficulties in performing daily activities point at the need of formal psychological and social care.

  20. Development of a preference-based index from the National Eye Institute Visual Function Questionnaire-25.

    Science.gov (United States)

    Rentz, Anne M; Kowalski, Jonathan W; Walt, John G; Hays, Ron D; Brazier, John E; Yu, Ren; Lee, Paul; Bressler, Neil; Revicki, Dennis A

    2014-03-01

    Understanding how individuals value health states is central to patient-centered care and to health policy decision making. Generic preference-based measures of health may not effectively capture the impact of ocular diseases. Recently, 6 items from the National Eye Institute Visual Function Questionnaire-25 were used to develop the Visual Function Questionnaire-Utility Index health state classification, which defines visual function health states. To describe elicitation of preferences for health states generated from the Visual Function Questionnaire-Utility Index health state classification and development of an algorithm to estimate health preference scores for any health state. Nonintervention, cross-sectional study of the general community in 4 countries (Australia, Canada, United Kingdom, and United States). A total of 607 adult participants were recruited from local newspaper advertisements. In the United Kingdom, an existing database of participants from previous studies was used for recruitment. Eight of 15,625 possible health states from the Visual Function Questionnaire-Utility Index were valued using time trade-off technique. A θ severity score was calculated for Visual Function Questionnaire-Utility Index-defined health states using item response theory analysis. Regression models were then used to develop an algorithm to assign health state preference values for all potential health states defined by the Visual Function Questionnaire-Utility Index. Health state preference values for the 8 states ranged from a mean (SD) of 0.343 (0.395) to 0.956 (0.124). As expected, preference values declined with worsening visual function. Results indicate that the Visual Function Questionnaire-Utility Index describes states that participants view as spanning most of the continuum from full health to dead. Visual Function Questionnaire-Utility Index health state classification produces health preference scores that can be estimated in vision-related studies that

  1. Ruolo delle nuove tecnologie basate sugli ultrasuoni nella valutazione dell'ipertensione portale nei pazienti con epatopatia cronica

    OpenAIRE

    Allegretti, Giulia

    2017-01-01

    Introduzione – Nei pazienti con epatopatia cronica, l'ipertensione portale rappresenta la causa delle principali complicanze (sanguinamento da varici, ascite, encefalopatia epatica) che, insieme all’epatocarcinoma, costituiscono la causa più importante di ospedalizzazione e mortalità. Le metodiche gold-standard per la valutazione dell’ipertensione portale sono la misurazione del gradiente di pressione venosa epatica (HVPG) mediante cateterismo delle vene sovraepatiche e l’esofagogastroduodeno...

  2. Eyes on the Solar System

    Data.gov (United States)

    National Aeronautics and Space Administration — Eyes on the Solar System is a software package developed by NASA Jet Propulsion Laboratory and the California Institute of Technology using data provided by NASA's...

  3. The Visual System

    Medline Plus

    Full Text Available ... First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about ...

  4. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about ...

  5. Glaucoma

    Medline Plus

    Full Text Available ... the special health problems and requirements of the blind.” News & Events Events Calendar NEI Press Releases News ... Videos Home Age-Related Macular Degeneration Amblyopia Animations Blindness Cataract Convergence Insufficiency Diabetic Eye Disease Dilated Eye ...

  6. The Visual System

    Medline Plus

    Full Text Available ... the special health problems and requirements of the blind.” News & Events Events Calendar NEI Press Releases News ... First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks ...

  7. Treatment outcomes in the DRy Eye Amniotic Membrane (DREAM study

    Directory of Open Access Journals (Sweden)

    McDonald MB

    2018-04-01

    Full Text Available Marguerite B McDonald,1 Hosam Sheha,2–5 Sean Tighe,2,3 Susan B Janik,6 Frank W Bowden,7 Amit R Chokshi,8 Michael A Singer,9 Seema Nanda,10 Mujtaba A Qazi,11 Damon Dierker,12 Adam T Shupe,13 Brittany J McMurren14 1Ophthalmic Consultants of Long Island, Lynbrook, NY, USA; 2Ocular Surface Center and TissueTech, Inc., Miami, FL, USA; 3Florida International University Herbert Wertheim College of Medicine, Miami, FL, USA; 4Hofstra University School of Medicine, Hempstead, NY, USA; 5Research Institute of Ophthalmology, Cairo, Egypt; 6Solinsky Eye Care, Kensington, CT, USA; 7Bowden Eye & Associates, Jacksonville, FL, USA; 8Florida Eye Specialists, Jacksonville, FL, USA; 9Medical Center Ophthalmology Associates, San Antonio, TX, USA; 10TX Eye Institute, Houston, TX, USA; 11Pepose Vision Institute, Chesterfield, MO, USA; 12Eye Surgeons of Indiana, Indianapolis, IN, USA; 13Royo Eye Care, Marysville, CA, USA; 14Gordon and Weiss Vision Institute, San Diego, CA, USA Purpose: To evaluate the efficacy of cryopreserved amniotic membrane (CAM in reducing signs and symptoms of dry eye disease (DED in a large patient population. Methods: A retrospective chart review at 10 clinical sites was done of patients with refractory DED who received CAM and completed at least 3 months of follow-up. Data collected were demographics; medical history including previous and current ocular treatment, diagnosis, clinical presentations, comorbidity, duration and frequency of treatment with CAM; and concomitant medications. The primary outcome was the change in dry eye workshop (DEWS score after treatment. Results: A total of 97 eyes of 84 patients exhibited severe dry eye despite maximal medical treatments including topical artificial tears, cyclosporine-A, serum, antibiotics, and steroids. Patients manifested with superficial punctate keratitis (86%, filamentary keratitis (13%, exposure keratitis (19%, neurotrophic keratitis (2%, and corneal epithelial defect (7%. After CAM

  8. The Visual System

    Medline Plus

    Full Text Available ... The Visual System Ever wonder how your eyes work? Watch this video to learn how you’re able to see the world around you. Did You Know? On average, you blink about 15 to 20 times every minute. That’s up to 28,800 times a day! NEI Home Contact Us A-Z Site Map NEI on ...

  9. Intravitreal injection analysis at the Bascom Palmer Eye Institute: evaluation of clinical indications for the treatment and incidence rates of endophthalmitis

    Directory of Open Access Journals (Sweden)

    Ludimila L Cavalcante

    2010-05-01

    Full Text Available Ludimila L Cavalcante, Milena L Cavalcante, Timothy G Murray, Michael M Vigoda, Yolanda Piña, Christina L Decatur, R Prince Davis, Lisa C Olmos, Amy C Schefler, Michael B Parrott, Kyle J Alliman, Harry W Flynn, Andrew A MoshfeghiBascom Palmer Eye Institute, Department of Ophthalmology, University of Miami Miller School of Medicine, Miami, FL, USAObjective: To report the incidence of endophthalmitis, in addition to its clinical and microbiological aspects, after intravitreal injection of vascular-targeting agents.Methods: A retrospective review of a consecutive series of 10,142 intravitreal injections of vascular targeting agents (bevacizumab, ranibizumab, triamcinolone acetonide, and preservative-free triamcinolone acetonide between June 1, 2007 and January 31, 2010, performed by a single service (TGM at the Bascom Palmer Eye Institute.Results: One case of clinically-suspected endophthalmitis was identified out of a total of 10,142 injections (0.009%, presenting within three days of injection of bevacizumab. The case was culture-positive for Staphylococcus epidermidis. Final visual acuity was 20/40 after pars plana vitrectomy surgery.Conclusions: In this series, the incidence of culture-positive endophthalmitis after intravitreal injection of vascular agents in an outpatient setting was very low. We believe that following a standardized injection protocol, adherence to sterile techniques and proper patient follow-up are determining factors for low incidence rates.Keywords: endophthalmitis, intravitreal injections, vascular targeting agents 

  10. The effect of intravitreal injections on dry eye, and proposed management strategies

    Directory of Open Access Journals (Sweden)

    Laude A

    2017-08-01

    Full Text Available Augustinus Laude,1–3 Jimmy WK Lim,1,2 Vishwanath Srinagesh,4 Louis Tong2,5–7 1National Healthcare Group Eye Institute, Tan Tock Seng Hospital, 2Singapore Eye Research Institute, 3Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore; 4Krieger Eye Institute, Baltimore, MD, USA; 5Singapore National Eye Centre, 6Duke NUS Medical School, 7Yong Loo Lin School of Medicine, National University of Singapore, Singapore Abstract: Intravitreal injection of anti-vascular endothelial growth factor (anti-VEGF agents has become a commonly used treatment method for a number of ophthalmic conditions, including age-related macular degeneration. Although anti-VEGF therapy has shown promising results for many patients, there are several aspects of its application that have not been thoroughly investigated. One of these is the development and/or escalation of concurrent dry eye syndrome. Many patients undergoing treatment are already predisposed to dry eye disease due to their age and overall ocular health. As dry eye can have a substantial impact on quality of life, it has become increasingly apparent that the clinical signs and symptoms should be closely monitored and aggressively managed. This will allow for the optimization of patient comfort and visual potential. Here, we discuss the reasons why dry eye may develop during the course of repeated ocular anti-VEGF therapy, highlighting the key concerns about current practices and proposing possible solutions to improve the outcome for the patients. Keywords: age-related macular degeneration, povidone–iodine, toxicity, ocular health, chronic ophthalmic treatment

  11. Collie eye anomaly: a review

    Czech Academy of Sciences Publication Activity Database

    Palánová, Anna

    2015-01-01

    Roč. 60, č. 7 (2015), s. 345-350 ISSN 0375-8427 R&D Projects: GA MŠk ED2.1.00/03.0124 Institutional support: RVO:67985904 Keywords : hereditary * eye * disease * dog Subject RIV: GJ - Animal Vermins ; Diseases, Veterinary Medicine Impact factor: 0.560, year: 2015

  12. 75 FR 64359 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

    Science.gov (United States)

    2010-10-19

    ... environmental impact statement or environmental assessment need be prepared for these amendments. If the... authorization to upgrade selected Emergency Action Levels based on Nuclear Energy Institute (NEI) 99-01... of NRC Regulatory Issue Summary 2003-18, Supplement 2, ``Use of Nuclear Energy Institute (NEI) 99-01...

  13. 78 FR 1267 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses and Combined Licenses...

    Science.gov (United States)

    2013-01-08

    ... CFR 51.22(b), no environmental impact statement or environmental assessment need be prepared for these.... The operational and management controls, as described in Nuclear Energy Institute (NEI) 08-09... in Nuclear Energy Institute (NEI) 08-09, Revision 6, would be implemented concurrent with the full...

  14. 77 FR 38094 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses and Combined Licenses...

    Science.gov (United States)

    2012-06-26

    ... 10 CFR 51.22. Therefore, pursuant to 10 CFR 51.22(b), no environmental impact statement or... DAEC Emergency Action Levels based on Nuclear Energy Institute (NEI) 99-01, Revision 5, ``Methodology...-18, Supplement 2, ``Use of Nuclear Energy Institute (NEI) 99-01, ``Methodology for Development of...

  15. Coping with dry eyes: a qualitative approach.

    Science.gov (United States)

    Yeo, Sharon; Tong, Louis

    2018-01-16

    Dry eye is a common problem that affects many people worldwide, reducing quality of life and impacting daily activities. A qualitative approach often used in medicine and other disciplines is used to evaluate how people with dry eye cope with this impact. Six focus group sessions were conducted at the Singapore National Eye Centre (SNEC), premises of an eye research institute. These focus groups consist of a spectrum of dry eye sufferers (30 women, 8 men, aged 61 ± 11.8 years). Standard methods of coding followed by determination of themes were adhered to. Where classification was difficult, consensus was made between 3 assessors. Audio-recorded transcripts were coded in 10 themes by 3 assessors independently. Four of the themes involved traditional measures such as lid warming, cleansing, lubrication and oral dietary supplements. The other themes discovered were Traditional Chinese Medicine, modification of eye-care habits (e.g. wearing sunglasses), environmental humidity, lifestyle (e.g. sleeping habits), psychological attitude, and lastly sharing and communication. Holistic coping strategies were found to be prominent in dry eye sufferers from these focus groups, and people tend to find personalised ways of coping with the impact of dry eye on daily living.

  16. EVALUATION OF DRY EYES IN DIABETES MELLITUS

    Directory of Open Access Journals (Sweden)

    Anshu Sharma

    2017-12-01

    Full Text Available BACKGROUND According to the National Eye Institute, dry eye is a condition in which the eye does not produce tears properly. It can also involve tears not having the right consistency or evaporating too quickly. Tears are necessary to help maintain moisture on the surface of the eye and for clear vision. Diabetes is often associated with several significant ocular conditions such as retinopathy, refractive changes, cataracts, glaucoma and macular oedema. However, one of the most common ocular complications associated with diabetes is dry eye. The aim of the study is to study the prevalence of dry eyes in diabetes mellitus and to evaluate ocular and other risk factors relevant to diabetic dry eyes. MATERIALS AND METHODS A hospital-based cross-sectional clinical study of 100 diabetic patients who presented to the Department of Ophthalmology, Santosh Medical College and Hospital, Ghaziabad, between January 2016 to June 2017 was conducted. Detailed diabetic history was recorded. Assessment of anterior segment via slit-lamp biomicroscopy was done. The examinations for dry eyes included Schirmer's test, tear breakup time, fluorescein and rose Bengal staining. RESULTS Sixty two (62% diabetic patients had dry eye. The prevalence in type I was 3% and prevalence in type II was 59%. Dry eye prevalence was maximum in those above 40 years of age. Symptoms like reduced corneal sensation (44% and meibomitis (20% were major attributable risk factors. Ocular surface damage was predominantly superficial punctate keratitis. Retinopathy was not statistically associated with the prevalence of dry eyes. CONCLUSION Diabetes and dry eye appears to be a common association. Reduction in the modifiable risk factors of dry eye is essential to reduce its prevalence. No significant statistical correlation was found between retinopathy and dry eyes. However, examination for dry eyes should be an integral part of the assessment of diabetic eye disease.

  17. Impact of dry eye on work productivity

    Directory of Open Access Journals (Sweden)

    Yamada M

    2012-10-01

    Full Text Available Masakazu Yamada, Yoshinobu Mizuno, Chika ShigeyasuNational Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center, Tokyo, JapanBackground: The purpose of this study was to evaluate the impact of dry eye on work productivity of office workers, especially in terms of presenteeism.Methods: A total of 396 individuals aged ≥20 years (258 men and 138 women, mean age 43.4 ± 13.0 years were recruited through an online survey. Data from 355 responders who did not have missing values were included in the analysis. They were classified into the following four groups according to the diagnostic status and subjective symptoms of dry eye: a definite dry eye group; a marginal dry eye group; a self-reported dry eye group; and a control group. The impact of dry eye on work productivity was evaluated using the Japanese version of the Work Limitations Questionnaire. The cost of work productivity loss associated with dry eye and the economic benefits of providing treatment for dry eye were also assessed.Results: The degree of work performance loss was 5.65% in the definite dry eye group, 4.37% in the marginal dry eye group, 6.06% in the self-reported dry eye group, and 4.27% in the control group. Productivity in the self-reported dry eye group was significantly lower than that in the control group (P < 0.05. The annual cost of work productivity loss associated with dry eye was estimated to be USD 741 per person.Conclusion: Dry eye impairs work performance among office workers, which may lead to a substantial loss to industry. Management of symptoms of dry eye by providing treatment may contribute to improvement in work productivity.Keywords: burden of disease, dry eye, presenteeism, quality of life

  18. Laser Eye Surgery: MedlinePlus Health Topic

    Science.gov (United States)

    ... corneal surgery - discharge (Medical Encyclopedia) Also in Spanish Topic Image MedlinePlus Email Updates Get Laser Eye Surgery ... surgery - what to ask your doctor Related Health Topics Refractive Errors National Institutes of Health The primary ...

  19. Longitudinal Vision-Related Quality of Life for Patients with Noninfectious Uveitis Treated with Fluocinolone Acetonide Implant or Systemic Corticosteroid Therapy.

    Science.gov (United States)

    Sugar, Elizabeth A; Venugopal, Vidya; Thorne, Jennifer E; Frick, Kevin D; Holland, Gary N; Wang, Robert C; Almanzor, Robert; Jabs, Douglas A; Holbrook, Janet T

    2017-11-01

    To evaluate longitudinal vision-related quality of life (VRQoL) in patients with noninfectious uveitis. Cohort study using randomized controlled trial data. Patients with active or recently active intermediate uveitis, posterior uveitis, or panuveitis enrolled in the Multicenter Steroid Treatment Trial and Follow-up Study. Data from the 25-item National Eye Institute Visual Functioning Questionnaire (NEI-VFQ-25) for the first 3 years after randomization were evaluated semiannually. Analyses were stratified by assigned treatment (129 implants vs. 126 systemic therapies) because of substantial differences in the trajectories of VRQoL. The impact of baseline measurements of visual function (visual acuity and visual field), demographics, and disease characteristics was assessed using generalized estimating equations. Primary outcome was the NEI-VFQ-25 composite score over 3 years after randomization. Individuals in both treatment groups showed similar improvement in NEI-VFQ-25 scores after 3 years of follow-up (implant: 11.9 points; 95% confidence interval [CI], 8.6-15.2; P treatment groups. In the systemic group, these differences were maintained throughout follow-up. In the implant group, individuals with initial visual acuity worse than 20/40 showed additional improvement in NEI-VFQ-25 score to come within -7 points (95% CI, -15.0 to 0.9) of those with visual acuity 20/40 or better initially, a clinically meaningful but not statistically significant difference (P = 0.081). Results based on sensitivity analyses showed similar patterns. Both treatment groups demonstrated significant improvements in NEI-VFQ-25 scores; however, the improvement was immediate for the implant group as opposed to gradual for the systemic group. Poorer visual function was associated significantly with initial differences in NEI-VFQ-25 scores. However, only individuals in the implant group with poor visual acuity were able to overcome their initial deficits by the end of 3 years

  20. Health-related quality of life and binocular vision in patients with diplopia in acute-onset comitant esotropia with press-on prism improves

    Directory of Open Access Journals (Sweden)

    Qian Wang

    2017-11-01

    Full Text Available AIM: To assess the effect of press-on prisms in patients with acute-onset comitant esotropia and diplopia, focusing primarily on vision-related quality of life and binocular vision. METHODS: Retrospective case-series study. Totally 16 acute-onset comitant esotropia patients with diplopia who received treatment in the Huzhou Central Hospital were included in this study from March 2014 to March 2017. Vision-related quality of life before press-on prism correction and 1mo after press-on prism correction were performed with the Chinese version of the 25-item National Eye Institute Visual Functioning Questionnaire(CHI-NEI-VFQ-25. In each time of follow-up, we made a minute examination, includes worth four dot test and stereo tests. Data was statistically analyzed with paired sample t test, Chi-square test and Fisher's exact test. RESULTS: Except the degree of eye pain, color vision and perimetry, the indicators from CHI-NEI-VFQ-25 table including general health status, overall vision, mental health, social role difficulties, social functional, near activities, distant activities, independency and driving of acute-onset comitant esotropia patients with diplopia were obviously significant improved 1mo after press-on prism correction(PPCONCLUSION: Press-on prism correction may be helpful for binocular vision recovery in acute-onset comitant esotropia patients with diplopia, so as improve the vision-related quality of life.

  1. Glaucoma

    Medline Plus

    Full Text Available ... from NEI Grantees Spokesperson bios Statistics and Data ... to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  2. The Visual System

    Medline Plus

    Full Text Available ... from NEI Grantees Spokesperson bios Statistics and Data ... addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  3. 78 FR 25458 - National Eye Institute; Notice of Meeting

    Science.gov (United States)

    2013-05-01

    ... public as indicated below, with attendance limited to space available. Individuals who plan to attend and... secrets or commercial property such as patentable material, and personal information concerning... be presentations by the staff of the Institute and discussions concerning Institute programs. Place...

  4. Are vision-specific quality of life questionnaires important in assessing rehabilitation for patients with hemianopia post stroke?

    Science.gov (United States)

    George, Stacey; Hayes, Allison; Chen, Celia; Crotty, Maria

    2011-01-01

    To explore the relationship between disability and functional measures with vision-specific quality of life (QoL) measures for people with hemianopia and stroke. The Behavioral Inattention Test (BIT) and the Mayo-Portland Adaptability Inventory (MPAI) were compared with scores on 2 vision-specific QoL measures, the National Eye Institute Visual Function Questionnaire (NEI VFQ-25) and Veteran Low Vision Visual Function Questionnaire (VA LV VFQ-48). Rehabilitation hospitals in Adelaide, South Australia. Stroke patients (n = 24) with homonymous hemianopia. Most of the BIT and MPAI scores were significantly associated with the NEI VFQ-25 and VA LV VFQ-48 scores. Behavioral test scores of the BIT and the MPAI total score correlated with more aspects of the QoL measures than the other components of the BIT and the MPAI. BIT and MPAI measure constructs associated with QoL for people with hemianopia following stroke. Vision-specific QoL questionnaires can complement the functional instruments by identifying the domains of difficulty, based on the instrument's subscale, that can guide rehabilitation therapists to address the person's deficit.

  5. 78 FR 73867 - National Eye Institute; Notice of Meeting

    Science.gov (United States)

    2013-12-09

    ... open to the public as indicated below, with attendance limited to space available. Individuals who plan... discussions could disclose confidential trade secrets or commercial property such as patentable material, and... concerning Institute programs. Place: National Institutes of Health, Rockledge II Building, Room 9100/9104...

  6. Eye scanning activity influenced by temperament traits

    Czech Academy of Sciences Publication Activity Database

    Lukavský, Jiří

    2005-01-01

    Roč. 34, - (2005), s. 121 ISSN 0301-0066. [European Conference on Visual Perception 2005. 22.08.2005-26.08.2005] Institutional research plan: CEZ:AV0Z70250504 Keywords : Eye movements * scanning * temperament * TCI-R * Rorschach test Subject RIV: AN - Psychology

  7. Five years of proton therapy of tumours of the eye at Hahn-Meitner Institute, Berlin; Fuenf Jahre Protonentherapie von Augentumoren am Hahn-Meitner-Institut Berlin

    Energy Technology Data Exchange (ETDEWEB)

    Heufelder, J.; Cordini, D.; Heese, J.; Homeyer, H.; Kluge, H.; Morgenstern, H. [Hahn-Meitner-Inst. Berlin, Augentumortherapie (Germany); Fuchs, H. [Hahn-Meitner-Inst. Berlin, Augentumortherapie (Germany); Augenklinik, Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin (Germany); Hoecht, S.; Nausner, M.; Hinkelbein, W. [Klinik fuer Radioonkologie und Strahlentherapie, Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin (Germany); Bechrakis, N.E.; Foerster, M.H. [Augenklinik, Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin (Germany)

    2004-07-01

    Eye tumors (choroidal melanomas, iris melanomas, and choroidal hemangiomas) are being treated with 68 MeV protons since 1998 at the Ion Beam Laboratory of the Hahn-Meitner Institute of Berlin (Germany's first proton therapy center), in cooperation with the Charite University Hospital in Berlin, Campus Benjamin Franklin. The proton beam, generated via a combination of Van de Graaff accelerator and cyclotron, is prepared by passive shaping for conformal tumor irradiation. A digital X-ray verification of the tumor location with the patient in sitting position limits the position uncertainties to a maximum of 0,3 mm. The treatment planning is performed using the program EYEPLAN. OCTOPUS, a CT-based planning program developed in cooperation with the German Cancer Research Center of Heidelberg, is under pre-clinical testing. Thus far, more than 400 patients have been irradiated. The first results are comparable to those obtained in other proton therapy centers. At the end of 2002, the University Hospital of Essen has also become a cooperation partner of the Hahn-Meitner Institute. (orig.) [German] Seit 1998 werden am Ionenstrahllabor des Hahn-Meitner-Instituts Berlin (Deutschlands erster Einrichtung zur Protonentherapie) im Rahmen eines Kooperationsvertrages mit der Charite - Universitaetsmedizin Berlin, Campus Benjamin Franklin, Augentumoren (Aderhautmelanome, Irismelanome und Aderhauthaemangiome) mit 68-MeV-Protonen bestrahlt. Der mittels einer Kombination aus Van de Graaff-Beschleuniger und Zyklotron erzeugte Protonenstrahl wird passiv fuer eine konformale Bestrahlung des Tumors aufbereitet. Eine digitale Roentgenkontrolle der Lagerung des sitzenden Patienten beschraenkt die Lagerungsunsicherheit auf maximal 0,3 mm. Fuer die Bestrahlungsplanung wird das modellbasierte Planungsprogramm EYEPLAN verwendet. In vorklinischer Erprobung befindet sich das mit dem Deutschen Krebsforschungszentrum Heidelberg entwickelte CT-basierte Planungsprogramm OCTOPUS. Bisher wurden

  8. Exploring interoperability: The advancements and challenges of improving data discovery, access, and visualization of scientific data through the NOAA Earth Information System (NEIS). (Invited)

    Science.gov (United States)

    Stewart, J.; Lynge, J.; Hackathorn, E.; MacDermaid, C.; Pierce, R.; Smith, J.

    2013-12-01

    Interoperability is a complex subject and often leads to different definitions in different environments. An interoperable framework of web services can improve the user experience by providing an interface for interaction with data regardless of it's format or physical location. This in itself improves accessibility to data, fosters data exploration and use, and provides a framework for new tools and applications. With an interoperable system you have: -- Data ready for action. Services model facilitates agile response to events. Services can be combined or reused quickly, upgraded or modified independently. -- Any data available through an interoperable framework can be operated on or combined with other data. Integrating standardized formats and access. -- New and existing systems have access to wide variety of data. Any new data added is easily incorporated with minimal changes required. The possibilities are limitless. The NOAA Earth Information System (NEIS) at the Earth System Research Laboratory (ESRL) is continuing research into an interoperable framework of layered services designed to facilitate the discovery, access, integration, visualization, and understanding of all NOAA (past, present, and future) data. An underlying philosophy of NEIS is to take advantage of existing off-the-shelf technologies and standards to minimize development of custom code allowing everyone to take advantage of the framework to meet these goals above. This framework, while built by NOAA are not limited to NOAA data or applications. Any other data available through similar services or applications that understand these standards can work interchangeably. Two major challenges are under active research at ESRL are data discoverability and fast access to big data. This presentation will provide an update on development of NEIS, including these challenges, the findings, and recommendations on what is needed for an interoperable system, as well as ongoing research activities

  9. EyeMusic: Making Music with the Eyes

    OpenAIRE

    Hornof, Anthony J.; Sato, Linda

    2004-01-01

    Though musical performers routinely use eye movements to communicate with each other during musical performances, very few performers or composers have used eye tracking devices to direct musical compositions and performances. EyeMusic is a system that uses eye movements as an input to electronic music compositions. The eye movements can directly control the music, or the music can respond to the eyes moving around a visual scene. EyeMusic is implemented so that any composer using established...

  10. Evaluation of vision-specific quality-of-life in albinism.

    Science.gov (United States)

    Kutzbach, Beth R; Merrill, Kimberly S; Hogue, Kathy M; Downes, Sara J; Holleschau, Ann M; MacDonald, John T; Summers, C Gail

    2009-04-01

    Human albinism is a genetic condition associated with visual impairment that affects many aspects of daily life. Office measurements of visual acuity do not necessarily reflect daily visual function and health status. This study used the National Eye Institute Visual Function Questionnaire (NEI-VFQ) to determine the effect of albinism-associated ophthalmopathy on quality of life (QOL). We administered the NEI-VFQ, which consists of 25 questions about QOL (VFQ-25) and 14 questions about well-being (VFQ-39), to 44 consenting participants with albinism older than the age of 18 years. Nineteen male and 25 female subjects completed the study. Median age was 30.5 years (range, 18-79 years). Mean best-corrected visual acuity was 20/83 (range, 20/20 to 20/320). Forty-eight percent reported that they were currently able to drive with their condition. Participants perceived midscale problems with their general vision (median subscale score 60.0). Visual acuity correlated moderately with overall NEI-VFQ composite scores (r(s) = 0.40, p = 0.01 for VFQ-25 and r(s) = 0.36, p = 0.02 for VFQ-39). Most notable impairment was recorded for distance acuity, vision-specific mental health, and vision-specific role difficulties (VFQ-39 median subscale scores 66.7, 70.0, and 75.0, respectively). Differences by sex were insignificant. Greater ceiling effects were noted for the VFQ-25 than for the VFQ-39. The NEI-VFQ-39 is a method to evaluate self-reported effects of vision-related QOL in albinism and may be used as a baseline for evaluating outcomes in interventional studies in these patients.

  11. Treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop: Prospective double-blind randomized study.

    Science.gov (United States)

    Moscovici, Bernardo Kaplan; Holzchuh, Ricardo; Sakassegawa-Naves, Fernando Eiji; Hoshino-Ruiz, Diego Ricardo; Albers, Marcos Bottene Villa; Santo, Ruth Miyuki; Hida, Richard Yudi

    2015-10-01

    To describe the clinical efficacy of the treatment of Sjögren's syndrome dry eye using 0.03% tacrolimus eye drop. Prospective double-blind randomized study. Institutional outpatient clinic. Forty-eight eyes of twenty-four patients with dry eye related to Sjögren syndrome were enrolled in this study. The patients were randomized in 2 groups: tacrolimus (n=14) and vehicle (n=10) group. The tacrolimus group received a vial containing tacrolimus 0.03% (almond oil as vehicle) and the other group received the almond oil vehicle. All patients were instructed to use the eye drops every 12h in the lower conjunctival sac. Schirmer I test, break-up-time (BUT), corneal fluorescein and Rose Bengal staining scores were evaluated in all patients one day before the treatment (baseline), 7, 14, 28 and 90 days after treatment with the eye drops. The average fluorescein and Rose Bengal scores improved statistically after 7 days of treatment and even more after 90 days. The average Schirmer I and BUT values were unchanged after 7, 14 and 21 days but did show an improvement relative to baseline after 28 days of treatment. Schirmer I, BUT, fluorescein and Rose Bengal did not show any statistical significance in the vehicle group. Topical 0.03% tacrolimus eye drop improved tear stability and ocular surface status in cases of inflammatory or SS-related dry eye. ClinicalTrials.gov Identifier: NCT01850979. Copyright © 2015 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  12. Connecting eye to eye

    DEFF Research Database (Denmark)

    Dau, Susanne; Rask, Anders Bindslev

    2017-01-01

    Computer Supported Collaborative Learning (CSCL) is used a frame for supporting online and blended learning in educations. The online communication and collaboration are afforded by the social collaboration. However, the social collaboration is based on the establishment of direct eye contact...... (Khalid, Deska & Hugenberg, 2016), but direct eye contact is challenged by the position of the digital devices and thus CSCL. Lack of eye contact is the chief contributor to the negative effects of online disinhibition (Lapidot-Lefler & Barak, 2012) and the problem is the location of the web camera...... at the computer. Eye contact is challenged by the displacement between the senders´ and receivers´ focus on the screen picture and the camera's location at the top or bottom of screens on all digital devices. The aim of this paper is accordingly to investigate the influence of the displacement in eye contact...

  13. Eye Allergies

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Eye Allergies Sections What Are Eye Allergies? Eye Allergy Symptoms ... allergy diagnosis Eye allergy treatment What Are Eye Allergies? Leer en Español: ¿Qué son las alergias de ...

  14. Addendum report of the JHPS expert committee on radiation protection of the lens of the eye (1). Eye lens dosimetry R and D, and radiation management and estimated eye-lens exposure for workers in Japanese nuclear power plants

    International Nuclear Information System (INIS)

    Akahane, Keiichi; Tatsuzaki, Hideo; Iimoto, Takeshi; Ichiji, Takeshi; Hamada, Nobuyuki; Iwai, Satoshi; Ohguchi, Hiroyuki; Ohno, Kazuko; Katoh, Masahiro; Kurosawa, Tadahiro; Kawaura, Chiyo; Tsujimura, Norio; Hayashida, Toshiyuki; Hotta, Yutaka; Yamasaki, Tadashi; Yokoyama, Sumi

    2015-01-01

    The Expert Committee on Radiation Protection of the Lens of the Eye was established under the Japan Health Physics Society in April, 2013 (completed, March, 2015). The Committee looked at new/revised documents and standards related to the eye lens published by international organizations such as the International Commission on Radiological Protection (ICRP) and the International Commission on Radiation Units and Measurements (ICRU). The Committee also examined recent and previous studies related to eye-lens radiation exposure and dosimetry in Japan. These findings were published in this journal as the Interim Report of the Committee. Since then, the Committee expanded its activity to give an overview the current progress of eye-lens dosimetry R and D at the National Institute of Advanced Industrial Science and Technology, along with research related to radiation management and estimated eye-lens exposure of Japanese nuclear-power-plant workers (including those at Fukushima Daiichi Nuclear Power Plant) for publishing an addendum Committee report. These additional findings are reported here. (author)

  15. Assessing quality of life in the treatment of patients with age-related macular degeneration: clinical research findings and recommendations for clinical practice.

    Science.gov (United States)

    Yuzawa, Mitsuko; Fujita, Kyoko; Tanaka, Erika; Wang, Edward C Y

    2013-01-01

    The importance of incorporating quality-of-life (QoL) assessments into medical practice is growing as health care practice shifts from a "disease-based" to a "patient-centered" model. The prevalence of age-related macular degeneration (AMD) is increasing in today's aging population. The purpose of this paper is: (1) to discuss, by reviewing the current literature, the impact of AMD on patients' QoL and the utility of QoL assessments in evaluating the impact of AMD and its treatment; and (2) to make a recommendation for incorporating QoL into clinical practice. We conducted a PubMed and an open Internet search to identify publications on the measurement of QoL in AMD, as well as the impact of AMD and the effect of treatment on QoL. A total of 28 articles were selected. AMD has been found to cause a severity-dependent decrement in QoL that is comparable to systemic diseases such as cancer, ischemic heart disease, and stroke. QoL impairment manifests as greater social dependence, difficulty with daily living, higher rates of clinical depression, increased risk of falls, premature admission to nursing homes, and suicide. The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25) is the most widely used eye disease-specific QoL instrument in AMD. It has been shown to correlate significantly with visual acuity (VA). QoL reflects aspects of AMD including psychological well-being, functional capacity, and the ability to perform patients' valued activities, which are not captured by a single, numerical VA score. The literature shows that the adverse impact of AMD on QoL is comparable to serious systemic disease. Eye disease-specific instruments for measuring QoL, such as the NEI VFQ-25, have shown a significant correlation of QoL decrement with measures of disease severity, as well as significant QoL improvement with treatment. The NEI VFQ-25 and other validated instruments provide a wide-ranging assessment of vision-related functioning that is important to

  16. How to Keep Your Sight for Life

    Science.gov (United States)

    ... vision), eye coordination, depth perception, focusing ability, and color vision. Common impairments to vision include near-sightedness, ... NEI). Vision loss ranks ahead of loss of memory, speech, arm or leg, and hearing. After all, ...

  17. Assessing quality of life in the treatment of patients with age-related macular degeneration: clinical research findings and recommendations for clinical practice

    Directory of Open Access Journals (Sweden)

    Yuzawa M

    2013-07-01

    Full Text Available Mitsuko Yuzawa,1 Kyoko Fujita,1 Erika Tanaka,2 Edward C Y Wang21Department of Ophthalmology, Nihon University School of Medicine, Surugadai, Kanda, Chiyoda-ku, Tokyo, Japan; 2Health Economics and Outcomes Research, Bayer Yakuhin Ltd, Marunouchi, Chiyoda-ku, Tokyo, JapanBackground: The importance of incorporating quality-of-life (QoL assessments into medical practice is growing as health care practice shifts from a “disease-based” to a “patient-centered” model. The prevalence of age-related macular degeneration (AMD is increasing in today’s aging population. The purpose of this paper is: (1 to discuss, by reviewing the current literature, the impact of AMD on patients’ QoL and the utility of QoL assessments in evaluating the impact of AMD and its treatment; and (2 to make a recommendation for incorporating QoL into clinical practice.Methods: We conducted a PubMed and an open Internet search to identify publications on the measurement of QoL in AMD, as well as the impact of AMD and the effect of treatment on QoL. A total of 28 articles were selected.Results: AMD has been found to cause a severity-dependent decrement in QoL that is comparable to systemic diseases such as cancer, ischemic heart disease, and stroke. QoL impairment manifests as greater social dependence, difficulty with daily living, higher rates of clinical depression, increased risk of falls, premature admission to nursing homes, and suicide. The National Eye Institute Visual Functioning Questionnaire (NEI VFQ-25 is the most widely used eye disease-specific QoL instrument in AMD. It has been shown to correlate significantly with visual acuity (VA. QoL reflects aspects of AMD including psychological well-being, functional capacity, and the ability to perform patients’ valued activities, which are not captured by a single, numerical VA score.Conclusion: The literature shows that the adverse impact of AMD on QoL is comparable to serious systemic disease. Eye disease

  18. Glaucoma

    Medline Plus

    Full Text Available ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  19. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  20. The Visual System

    Medline Plus

    Full Text Available ... maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | ...

  1. Staphylococcus aureus eye infections in two Indian hospitals: emergence of ST772 as a major clone

    Directory of Open Access Journals (Sweden)

    Nadig S

    2012-01-01

    Full Text Available Savitha Nadig1, Nithya Velusamy2, Prajna Lalitha2, Sarita Kar3, Savitri Sharma3, Gayathri Arakere11Society for Innovation and Development, Indian Institute of Science, Bengaluru, Karnataka, 2Aravind Eye Hospital, Madurai, Tamil Nadu, 3LV Prasad Eye Institute, Bhubaneswar, Odisha, IndiaPurpose: The purpose of this study was to perform molecular characterization of Staphylococcus aureus isolates causing a variety of eye infections from two major eye care hospitals in India.Methods: Twenty-four isolates from Aravind Eye Hospital, Madurai, India, and nine isolates from LV Prasad Eye Institute, Bhubaneswar, India, representing severe to nonsevere eye infections like microbial keratitis to lacrimal sac abscess, were characterized. Staphylococcal cassette chromosome mec typing, multilocus sequence typing, accessory gene regulator typing, staphylococcal protein A typing, and pulsed field gel electrophoresis were used, along with determination of the presence of Panton–Valentine leucocidin toxin and endotoxin gene cluster among each sequence type.Results: The majority of eye infections, both severe and nonsevere, were caused by sequence type (ST772, positive for the Panton–Valentine leucocidin gene, and carrying methicillin-resistant staphylococcal cassette chromosome mec type V cassette (22/33, 67%. Some of the other sequence types that caused severe eye infections were ST1 (9%, 5 (3%, 72 (6%, 88 (3%, 121 (3%, and 672 (3%. This is the first report of the presence of ST1 and 88 in India.Conclusion: Although the number of isolates included in this study was small, most of the eye infections were caused by community-associated S. aureus where patients had no history of hospitalization or treatment in the past year. In the case of six severe infections, patients were admitted for surgeries and there is probability of hospital infection. In addition, only methicillin-resistant S. aureus isolates carrying staphylococcal cassette chromosome mec type V were

  2. 76 FR 24499 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-05-02

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... discussions concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace...

  3. 77 FR 31032 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-05-24

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  4. 77 FR 73037 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-12-07

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... discussions concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace...

  5. 77 FR 55852 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-09-11

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  6. 75 FR 76474 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-12-08

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  7. 76 FR 53687 - National Eye Institute Notice of Closed Meeting

    Science.gov (United States)

    2011-08-29

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  8. 77 FR 2076 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-01-13

    ... the public as indicated below, with attendance limited to space available. Individuals who plan to... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: National Institutes of Health, 5635 Fishers Lane, Terrace Level...

  9. Análise da qualidade de vida de portadores de uveítes de causas infecciosas e não infecciosas pelo questionário NEI-VFQ-25 Analysis of the life quality of infectious and non-infectious patients with uveitis using the NEI-VFQ-25 questionnaire

    Directory of Open Access Journals (Sweden)

    Paula Resende Aquino de Assis Pereira Mello

    2008-12-01

    Full Text Available OBJETIVO: Avaliar a qualidade de vida dos pacientes portadores de uveítes infecciosas e não infecciosas avaliados no setor de uveíte do serviço de oftalmologia do Hospital Universitário Clementino Fraga Filho - UFRJ, por meio da aplicação do questionário NEI-VFQ-25, de modo a esclarecer melhor a importância do diagnóstico e tratamento das uveítes, assim como suas conseqüências na função visual e social dos pacientes. MÉTODOS: Estudo prospectivo composto de 30 pacientes com uveítes que foram divididos em dois grupos conforme a etiologia, infecciosa e não infecciosa, tendo sido aplicado duas vezes em cada paciente o questionário NEI-VFQ-25 que avalia a qualidade de vida relacionada à saúde geral e visual. RESULTADOS: A toxoplasmose foi a principal causa de uveíte infecciosa, enquanto a não infecciosa foi a síndrome de Vogt-Koyanagi-Harada. Quanto à qualidade de vida, a saúde geral é melhor no grupo de causa infecciosa, sendo que a saúde ocular é regular nos dois grupos. Apesar do déficit visual não provocar grandes distúrbios e restrições sociais, ambos os grupos apresentam comprometimento emocional importante, sendo que no grupo de causa não infecciosa, esse comprometimento gera grau maior de dependência para a realização de tarefas do cotidiano. CONCLUSÃO: A maior dependência social e na realização de atividades do dia-a-dia no grupo de uveítes de causa não infecciosas, se explica pelo modo crônico e recidivante dessas afecções, o que leva à qualidade de vida inferior se comparada ao outro grupo.PURPOSE: To evaluate the life quality of patients with infectious and non-infectious uveitis evaluated at the uveitis service of the Hospital Universitário Clementino Fraga Filho-UFRJ, using the NEI-VFQ-25 questionnaire in order to clarify the importance of uveitis diagnosis and treatment as well as its consequences to visual and social functions of the patients. METHODS: Prospective study of 30 patients

  10. Economics of institutions and transaction costs: implementation of some elements of the analysis of small-scale agribusiness.

    Directory of Open Access Journals (Sweden)

    Marcio Gazolla

    2009-12-01

    Full Text Available The purpose of this paper is to demonstrate how family agribusiness reproduces in rural areas of the country (with emphasis in Southern Brazil, even in some cases, under conditions of social and economic difficulties. Thus, this paper discusses the main issues related to maintaining social and economic developments of small agro-industrial by addressing them under the theoretical framework of institutionalism (The New Institutional Economics - NEI and Cost Economics Transaction (ECT. The research methodology included the use of a structured questionnaire with closed questions, search through the CAAF (CAAF, 2006 and semi-structured interviews with owners of families agribusinesses, applied both in Northern Rio Grande do Sul (Upper East Region of Uruguay. The findings show that the ECT and institutionalism are theoretical approaches that are consistent and provide good support in understanding the processes of reproduction and social maintenance of small-scale agro-industrial family, even in the face of production problems, market, organization, legislation.

  11. Use of computerized tomography in the Multibrauch Research and Technology Complex ''Eye microsurgery''

    International Nuclear Information System (INIS)

    Fedorov, S.N.; Ivashina, A.I.; Anisimov, S.I.; Prokopenko, L.N.; Moskvichev, A.L.

    1989-01-01

    The paper is devoted to analysis of the results of computerized tomography (CT) in 1000 patients examined in te Multibranch Research and Technology Complex ''Eye Microsurgery''. The specific feature of CT in this institution is that 52% of all investigations of ophthalmological patients fall to the share of eyeball abnormality and 40% - to a study of the other parts of the organ of vision. CT indications are extended for low tension glaucoma, complicated high myopia, and for monitoring the position of microsurgical implants. The use of CT is such a highly specialized medical institution as the MRTC ''Eye Microsurgery'' is considered indispensable

  12. The Visual System

    Medline Plus

    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  13. Glaucoma

    Medline Plus

    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  14. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov ...

  15. «Peripezia» ed «estasi della catastrofe»: figure della tragedia nei romanzi di Proust e Joyce

    Directory of Open Access Journals (Sweden)

    Raffaello Rossi

    2017-12-01

    Full Text Available L’articolo prende in esame la presenza di tematiche e strutture assimilabili all’estetica del tragico nelle opere di Marcel Proust e James Joyce,. Vengono in primo luogo confrontate le riflessioni sulla tragedia e sul concetto di tragico degli autori; successivamente viene considerato l’influsso esercitato da opere come la Phèdre di Racine e l’Hamlet shakespeariano, sia al livello di rimandi intertestuali nelle opere, che le loro effettive risonanze nei caratteri e trame della Recherche e di Ulysses. Si cerca infine di comprendere come il significato tragico degli eventi venga rielaborato al di là delle sue implicazioni estetiche.

  16. Energy and telecommunications public services; Servizi pubblici nei settori dell'energia e delle telecomunicazioni

    Energy Technology Data Exchange (ETDEWEB)

    Salini, M. P. [Ente Nazionale Idrocarburi SpA, Rapporti Istituzionali per l' Italia e l' Unione Europea, Milan (Italy)

    2001-03-01

    The aim of this work is the evolution of the energy and telecommunication public services. The article runs through the main stages in the public services' history and shows how open market rules may cause the future dissolution of public service notion. The conclusion wishes the hastening of public services privatisation and a Corporate Governance reform as a mean to pursue general interest. [Italian] Oggetto di questo lavoro e' l'evoluzione dei servizi pubblici nei settori dell'energia e delle telecomunicazioni. Se ne ripercorrono le principali tappe storiche e si evidenzia come le regole di apertura dei mercati possano causare la dissoluzione del concetto di servizio pubblico. Le conclusioni sottolineano la necessita' di accelerare la privatizzazione dei servizi pubblici e la riforma della Corporate Governance come strumento per il raggiungimento dell'interesse generale.

  17. Six Smart Things College Students Should Do for Their Eyes

    Science.gov (United States)

    ... Eye Institute Log In Forgot password | Forgot email Shop the Academy Store Focal Points 2018 Module: Neuro-Ophthalmic Disorders Caused By Medications Basic and Clinical Science Course Self-Assessment Program 2018-2019 Basic and ...

  18. Inter-eye comparison of retinal oximetry and vessel caliber between eyes with asymmetrical glaucoma severity in different glaucoma subtypes

    Directory of Open Access Journals (Sweden)

    Cheng CS

    2016-07-01

    Full Text Available Clarissa Shu Ming Cheng,1,2 Yi Fang Lee,2 Charles Ong,3 Zhu Li Yap,2 Andrew Tsai,2 Aditi Mohla,2 Monisha E Nongpiur,4 Tin Aung,2,4 Shamira A Perera2,4 1Department of Ophthalmology, Tan Tock Seng Hospital, 2Department of Ophthalmology, Singapore National Eye Centre, 3Yong Loo Lin School of Medicine, National University of Singapore, 4Singapore Eye Research Institute, Singapore National Eye Centre, Singapore Background: To compare retinal vessel oxygenation and vessel caliber in primary angle-closure glaucoma (PACG, primary open-angle glaucoma (POAG, normal-tension glaucoma (NTG, and normal controls, as well as between eyes of asymmetrical glaucoma severity.Methods: This was a prospective, cross-sectional study. The 159 subjects (PACG, n=39; POAG, n=41; NTG, n=41; normal controls, n=38 underwent retinal oxygen saturation measurements using the Oxymap T1 Retinal Oximeter, optical coherence tomography, and Humphrey visual field testing. Retinal oxygen saturation and vessel diameter were compared between the glaucoma groups and normal controls, as well as between eyes of asymmetrical glaucoma severity. Kruskal–Wallis test was performed for comparison among different subtypes of glaucoma. Wilcoxon signed-rank test was used to compare the inter-eye differences.Results: Compared to normal controls, arteriolar oxygen saturation was increased in PACG eyes (P=0.048 but not in POAG or NTG eyes. There were no significant differences in oxygen saturation in venules or arteriovenous (AV difference in all three glaucoma groups. Venular diameter was significantly reduced in all glaucoma groups compared to normal controls (P<0.001, but no such change was observed in arteriolar diameter (P=0.10. When comparing between eyes of asymmetrical glaucoma severity, arteriolar oxygen saturation (P=0.03 and AV difference (P=0.04 were significantly higher, while arteriolar diameter was significantly lower (P=0.001 in the worse eye in PACG group. There were no significant

  19. Effect of Autologous Serum Eye Drops in Patients with Sjögren Syndrome-related Dry Eye: Clinical and In Vivo Confocal Microscopy Evaluation of the Ocular Surface.

    Science.gov (United States)

    Semeraro, Francesco; Forbice, Eliana; Nascimbeni, Giuseppe; Taglietti, Marco; Romano, Vito; Guerra, Germano; Costagliola, Ciro

    To evaluate in vivo changes after therapy using autologous serum (AS) eye drops in Sjögren's syndrome (SS)-related dry eyes by confocal microscopy. In this study, 24 patients with SS-related dry eyes [12 in AS eye drop therapy and 12 in artificial tear (AT) therapy] and 24 healthy volunteers were recruited. Ocular Surface Disease Index (OSDI), central corneal thickness, tear film, break-up time, corneal and conjunctival staining, Schirmer's test and corneal confocal microscopy were investigated. Tear production, tear stability, corneal staining, inflammation, and central corneal thickness, Langherans cells, activated keratocytes, intermediate epithelial cell density, nerve tortuosity, number of sub-basal nerve branches, and number of bead-like formations differed between patients and controls (peye drops improve symptoms and confocal microscopy findings in SS-related dry eyes. Copyright © 2016 International Institute of Anticancer Research (Dr. John G. Delinassios), All rights reserved.

  20. Gene Profiling Technique to Accelerate Stem Cell Therapies for Eye Diseases

    Science.gov (United States)

    ... volumes. Dr. Bharti and colleagues at NEI are collaborating with the New York Stem Cell Foundation to ... from the NIH Common Fund, Dr. Bharti is leading efforts toward a clinical trial of iPS-derived ...

  1. The Visual System

    Medline Plus

    Full Text Available ... NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  2. Pax genes in eye development and evolution

    Czech Academy of Sciences Publication Activity Database

    Kozmik, Zbyněk

    2005-01-01

    Roč. 15, č. 4 (2005), s. 430-438 ISSN 0959-437X R&D Projects: GA MŠk(CZ) 1M0520; GA ČR(CZ) GA204/04/1358 Institutional research plan: CEZ:AV0Z5052915 Keywords : paxpax * eye development * evolution Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 9.361, year: 2005

  3. The Visual System

    Medline Plus

    Full Text Available ... NEI Women Scientists Advisory Committee (WSAC) Board of Scientific Counselors National Advisory Eye Council (NAEC) Donating to ... for the media Pressroom Contacts Dustin Hays - Chief, Science Communication dustin.hays@nih.gov Kathryn DeMott, Media ...

  4. 75 FR 18252 - Culturally Significant Object Imported for Exhibition Determinations: “Through African Eyes: The...

    Science.gov (United States)

    2010-04-09

    ... Determinations: ``Through African Eyes: The European in African Art, 1500--Present'' SUMMARY: Notice is hereby... object to be included in the exhibition ``Through African Eyes: The European in African Art, 1500... determine that the exhibition or display of the exhibit object at the Detroit Institute of Arts, Detroit...

  5. Impact of Glaucoma and Dry Eye on Text-Based Searching

    Science.gov (United States)

    Sun, Michelle J.; Rubin, Gary S.; Akpek, Esen K.; Ramulu, Pradeep Y.

    2017-01-01

    Purpose We determine if visual field loss from glaucoma and/or measures of dry eye severity are associated with difficulty searching, as judged by slower search times on a text-based search task. Methods Glaucoma patients with bilateral visual field (VF) loss, patients with clinically significant dry eye, and normally-sighted controls were enrolled from the Wilmer Eye Institute clinics. Subjects searched three Yellow Pages excerpts for a specific phone number, and search time was recorded. Results A total of 50 glaucoma subjects, 40 dry eye subjects, and 45 controls completed study procedures. On average, glaucoma patients exhibited 57% longer search times compared to controls (95% confidence interval [CI], 26%–96%, P Dry eye subjects demonstrated similar search times compared to controls, though worse Ocular Surface Disease Index (OSDI) vision-related subscores were associated with longer search times (P dry eye (P > 0.08 for Schirmer's testing without anesthesia, corneal fluorescein staining, and tear film breakup time). Conclusions Text-based visual search is slower for glaucoma patients with greater levels of VF loss and dry eye patients with greater self-reported visual difficulty, and these difficulties may contribute to decreased quality of life in these groups. Translational Relevance Visual search is impaired in glaucoma and dry eye groups compared to controls, highlighting the need for compensatory strategies and tools to assist individuals in overcoming their deficiencies. PMID:28670502

  6. Domains of health-related quality of life in age-related macular degeneration: a qualitative study in the Chinese cultural context

    Science.gov (United States)

    Bian, Wei; Wan, Junli; Smith, Graeme; Li, Shiying; Tan, Mingqiong; Zhou, Fengjiao

    2018-01-01

    Objective To explore which areas of health-related quality of life were affected in Chinese patients, and to identify whether the areas are well covered by validated questionnaires. Design A qualitative study based on semistructured interviews was conducted. A qualitative thematic analysis following the approach of Colaizzi was used to analyse the interview data for significant statements and phrases. The themes and subthemes organised from the analysis were then compared by using the following current instruments: National Eye Institute Visual Function Questionnaire (NEI-VFQ-25), Macular Disease Quality of life Questionnaire (MacDQoL) and Low-Luminance Questionnaire (LLD). Participants and setting Twenty-one patients with age-related macular degeneration were recruited from the eye clinic of Southwest Eye Hospital in Chongqing, mainland China. Results The mean age of the participants was 69.8 years (range 57–82 years) and the duration of the disease ranged from 3 months to 6 years. The qualitative analysis revealed nine important domains including symptoms, difficulties with daily activities, depending on others, depression and uncertainty, optimism and hope, social isolation, role change, family support and financial burden. However, all the three questionnaires were insufficient to capture the full extent of quality of life issues of Chinese patients with AMD, and MacDQoL covered more domains when compared with NEI-VFQ-25 and LLD. Conclusion The domains of concepts important to people with AMD in the Chinese culture are not fully represented in the three widely used questionnaires. Nine important domains were identified for the assessment of quality of life and should be considered when assessing the impact of AMD on Chinese individuals. Further studies are needed to develop an AMD quality of life questionnaire, better tailored to the needs and culture of Chinese patients. PMID:29666126

  7. 77 FR 47121 - Calvert Cliffs Nuclear Power Plant, LLC; Calvert Cliffs Nuclear Power Plant, Units 1 and 2...

    Science.gov (United States)

    2012-08-07

    ... for Nuclear Power Plant Personnel,'' endorses the Nuclear Energy Institute (NEI) report NEI 06-11...(c)(25). Pursuant to 10 CFR 51.22(b), no environmental impact statement or environmental assessment... hereafter in effect. The facility consists of two pressurized-water reactors (PWRs) located in Calvert...

  8. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ... Employee Emergency Information NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. ...

  9. Glaucoma

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for ...

  10. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for ...

  11. The Visual System

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for ...

  12. Watch Out for Glaucoma | NIH MedlinePlus the Magazine

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Glaucoma Watch Out for Glaucoma Past Issues / Spring 2015 Table of Contents A ... used to check eye pressure for signs of glaucoma. Photo courtesy of NEI Glaucoma is a group ...

  13. The Visual System

    Medline Plus

    Full Text Available ... Home » NEI for Kids » The Visual System Listen All About Vision About the Eye Ask a Scientist ... learn how you’re able to see the world around you. Did You Know? On average, you ...

  14. Glaucoma

    Medline Plus

    Full Text Available ... blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ...

  15. The Visual System

    Medline Plus

    Full Text Available ... blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ...

  16. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind.” ... DeMott, Media Relations Kathryn.DeMott@nih.gov NEI Office of Communications ( ...

  17. The role of Pax genes in eye evolution

    Czech Academy of Sciences Publication Activity Database

    Kozmik, Zbyněk

    2008-01-01

    Roč. 75, 2-4 (2008), s. 335-339 ISSN 0361-9230 R&D Projects: GA AV ČR IAA500520604; GA MŠk(CZ) 1M0520 Institutional research plan: CEZ:AV0Z50520514 Keywords : eye * Pax * evolution Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 2.281, year: 2008

  18. [Emphasis on standardization and refinement in the diagnosis and treatment of dry eye].

    Science.gov (United States)

    Liu, Z G

    2017-09-11

    Dry eye is the second most common ocular disease. In China, the incidence rate of dry eye has reached 21% to 30%, and dry eye patients have accounted for more than 30% of the total ophthalmology outpatients. Dry eye has become a common health problem that affects the working efficiency and life quality of Chinese people. Over the past decade, due to the rapid development of diagnostic equipments and new treatments for dry eye, dry eye has become one of the areas with greatest concerns in ophthalmology, and many eye institutions have set up their dry eye clinics. Although the diagnosis and treatment of dry eye has been improved in recent years, the awareness of dry eye in Chinese ophthalmologists is still too simple. In the diagnosis, the interrogation and basic examination are not given enough attention, and we are over-relying on equipments. Clinical examination and instrument operation also have not been standardized. This article emphasizes that we should pay attention to the interrogation, basic examination and standardization of clinical examination and equipment operation in diagnosing dry eye. The treatment regimen should be mostly refined and optimized to be individualized and comprehensive based on the causes, types and severity of dry eye. In addition, the physical and adjuvant therapy of dry eye should be given sufficient attention and applied reasonably. (Chin J Ophthalmol, 2017, 53: 641-644) .

  19. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... Are these common eye-related myths true or false? Click to Watch Why did you become a ... A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, Social Media ...

  20. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  1. Glaucoma

    Medline Plus

    Full Text Available ... with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  2. The Visual System

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    Full Text Available ... with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ... Contact Us A-Z Site Map NEI on Social Media Information in Spanish (Información en español) Website, ...

  3. Glaucoma

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is ...

  4. The Visual System

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is ...

  5. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office of the Scientific Director Sheldon S. ... NEI Intranet (Employees Only) *PDF files require the free Adobe® Reader® software for viewing. This website is ...

  6. Glaucoma

    Medline Plus

    Full Text Available ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  7. Ask a Scientist: What is Color Blindness?

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    Full Text Available ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  8. The Visual System

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    Full Text Available ... website is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  9. The Visual System

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    Full Text Available ... is maintained by the NEI Office of Science Communications, Public Liaison, and Education. Technical questions about this website can be addressed to the NEI Website Manager . Department of Health and Human Services | The National Institutes of Health | USA.gov NIH…Turning Discovery Into Health ®

  10. Eye Protection

    OpenAIRE

    Pashby, Tom

    1986-01-01

    Eye injuries frequently occur in the home, at work and at play. Many result in legally blind eyes, and most are preventable. Awareness of potential hazards is essential to preventing eye injuries, particularly in children. In addition, protective devices must be used appropriately. We have developed eye protectors that have proved effective in reducing both the overall incidence and the severity of sports eye injuries.

  11. Diabetes eye exams

    Science.gov (United States)

    Diabetic retinopathy - eye exams; Diabetes - eye exams; Glaucoma - diabetic eye exam; Macular edema - diabetic eye exam ... if the doctor who takes care of your diabetes checks your eyes, you need an eye exam ...

  12. Eye Absence Does Not Regulate Planarian Stem Cells during Eye Regeneration.

    Science.gov (United States)

    LoCascio, Samuel A; Lapan, Sylvain W; Reddien, Peter W

    2017-02-27

    Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm regeneration from diverse injuries. A long-standing question is whether neoblasts directly sense and respond to the identity of missing tissues during regeneration. We used the eye to investigate this question. Surprisingly, eye removal was neither sufficient nor necessary for neoblasts to increase eye progenitor production. Neoblasts normally increase eye progenitor production following decapitation, facilitating regeneration. Eye removal alone, however, did not induce this response. Eye regeneration following eye-specific resection resulted from homeostatic rates of eye progenitor production and less cell death in the regenerating eye. Conversely, large head injuries that left eyes intact increased eye progenitor production. Large injuries also non-specifically increased progenitor production for multiple uninjured tissues. We propose a model for eye regeneration in which eye tissue production by planarian stem cells is not directly regulated by the absence of the eye itself. Copyright © 2017 Elsevier Inc. All rights reserved.

  13. The Barrie Jones Lecture-Eye care for the neglected population: challenges and solutions.

    Science.gov (United States)

    Rao, G N

    2015-01-01

    Globally, pockets of 'neglected populations' do not have access to basic health-care services and carry a much greater risk of blindness and visual impairment. While large-scale public health approaches to control blindness due to vitamin A deficiency, onchocerciasis, and trachoma are successful, other causes of blindness still take a heavy toll in the population. High-quality comprehensive eye care that is equitable is the approach that needs wide-scale application to alleviate this inequity. L V Prasad Eye Institute of India developed a multi-tier pyramidal model of eye care delivery that encompasses all levels from primary to advanced tertiary (quaternary). This has demonstrated the feasibility of 'Universal Eye Health Coverage' covering promotive, preventive, corrective, and rehabilitative aspects of eye care. Using human resources with competency-based training, effective and cost-effective care could be provided to many disadvantaged people.

  14. 76 FR 34763 - Biweekly Notice; Applications and Amendments to Facility Operating Licenses Involving No...

    Science.gov (United States)

    2011-06-14

    ... approved [Nuclear Energy Institute (NEI)] 04-10, Rev. 1 in accordance with the TS SFCP. NEI 04-10, Rev. 1... environmental impact statement or environmental assessment need be prepared for these amendments. If the...'s property, financial, or other interest in the proceeding; and (4) the possible effect of any...

  15. Ask a Scientist: What is Color Blindness?

    Medline Plus

    Full Text Available ... Eye Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino Program Vision and Aging Program ... Jobs Fellowships NEI Summer Intern Program Diversity In Vision Research & Ophthalmology (DIVRO) Student Training Programs To search for current job openings visit ...

  16. Relationships Between Measures of the Ability to Perform Vision-Related Activities, Vision-Related Quality of Life, and Clinical Findings in Patients With Glaucoma.

    Science.gov (United States)

    Ekici, Feyzahan; Loh, Rebecca; Waisbourd, Michael; Sun, Yi; Martinez, Patricia; Nayak, Natasha; Wizov, Sheryl S; Hegarty, Sarah; Hark, Lisa A; Spaeth, George L

    2015-12-01

    To our knowledge, few studies have combined an objective measure of vision-related performance (VRP) and subjective measures of vision-related quality of life (VRQoL) with clinically related visual parameters, particularly in a large, prospective, cohort study setting. To examine the relationships between clinical visual assessments and both a VRP and 2 self-reported VRQoL measurements. Patients (N = 161) with moderate-stage glaucoma recruited from the Glaucoma Service at Wills Eye Hospital, Philadelphia, Pennsylvania, were enrolled from May 2012 to May 2014 in an ongoing prospective, 4-year longitudinal observational study. This report includes cross-sectional results from the baseline visit. Patients received a complete ocular examination, automated visual field (VF) test and Cirrus optical coherence tomographic scan. Contrast sensitivity was measured with the Pelli-Robson and the Spaeth-Richman Contrast Sensitivity (SPARCS) tests. Vision-related performance was assessed by the Compressed Assessment of Ability Related to Vision (CAARV) test. Vision-related QoL was assessed by the National Eye Institute Visual Function Questionnaire 25 (NEI-VFQ-25) and a modified Glaucoma Symptom Scale (MGSS). Correlations between clinical measures and CAARV, NEI-VFQ-25, and MGSS scores. A total of 161 patients were enrolled in the study. The strongest correlation was found between SPARCS score in the better eye and total CAARV score (r = 0.398; 95% CI, 0.235-0.537; P better eye. There were more statistically significant correlations between contrast sensitivity tests and VF mean deviation with VRQoL measurements than with other clinical measures (visual acuity, intraocular pressure, Disc Damage Likelihood Scale, and mean retinal nerve fiber layer thickness). The MGSS scores were lower (worse) in women compared with men (P = .03 for binocular, P = .01 for better eye, and P = .05 for the worse eye). Structural measures (eg, Disc Damage Likelihood Scale, and

  17. Eyes Wide Open

    Directory of Open Access Journals (Sweden)

    Zoi Manesi

    2016-04-01

    Full Text Available Research from evolutionary psychology suggests that the mere presence of eye images can promote prosocial behavior. However, the “eye images effect” is a source of considerable debate, and findings across studies have yielded somewhat inconsistent support. We suggest that one critical factor may be whether the eyes really need to be watching to effectively enhance prosocial behavior. In three experiments, we investigated the impact of eye images on prosocial behavior, assessed in a laboratory setting. Participants were randomly assigned to view an image of watching eyes (eyes with direct gaze, an image of nonwatching eyes (i.e., eyes closed for Study 1 and averted eyes for Studies 2 and 3, or an image of flowers (control condition. Upon exposure to the stimuli, participants decided whether or not to help another participant by completing a dull cognitive task. Three independent studies produced somewhat mixed results. However, combined analysis of all three studies, with a total of 612 participants, showed that the watching component of the eyes is important for decision-making in this context. Images of watching eyes led to significantly greater inclination to offer help as compared to images of nonwatching eyes (i.e., eyes closed and averted eyes or images of flowers. These findings suggest that eyes gazing at an individual, rather than any proxy to social presence (e.g., just the eyes, serve as a reminder of reputation. Taken together, we conclude that it is “eyes that pay attention” that can lift the veil of anonymity and potentially facilitate prosocial behavior.

  18. Survey of Ophthalmologists Regarding Practice Patterns for Dry Eye and Sjogren Syndrome.

    Science.gov (United States)

    Bunya, Vatinee Y; Fernandez, Karen B; Ying, Gui-Shuang; Massaro-Giordano, Mina; Macchi, Ilaria; Sulewski, Michael E; Hammersmith, Kristin M; Nagra, Parveen K; Rapuano, Christopher J; Orlin, Stephen E

    2018-01-15

    To survey ophthalmologists about current practice patterns regarding the evaluation of dry eye patients and referrals for a Sjogren syndrome (SS) workup. An online survey was sent to ophthalmologists affiliated with the Scheie Eye Institute or Wills Eye Hospital using REDCap in August 2015. Descriptive statistics were used to summarize the data. Four hundred seventy-four survey invitations were sent out and 101 (21%) ophthalmologists completed the survey. The common traditional dry eye test performed was corneal fluorescein staining (62%) and the most common newer dry eye test performed was tear osmolarity (18%). Half of respondents (51%) refer fewer than 5% of their dry eye patients for SS workups, with 18% reporting that they never refer any patients. The most common reasons for referrals included positive review of systems (60%), severe dry eye symptoms (51%) or ocular signs (47%), or dry eye that is refractory to treatment (42%). The majority (83%) felt that there is a need for an evidence-based standardized screening tool for dry eye patients to decide who should be referred for evaluation for SS. Ophthalmologists continue to prefer the use of traditional dry eye tests in practice, with the most common test being corneal fluorescein staining. There is an underreferral of dry eye patients for SS workups, which is contributing to the continued underdiagnosis of the disease. Most respondents felt that there was a need for an evidence-based standardized screening tool to decide which dry eye patients should be referred for SS evaluations.

  19. Saccadic eye movement applications for psychiatric disorders

    Directory of Open Access Journals (Sweden)

    Bittencourt J

    2013-09-01

    Full Text Available Juliana Bittencourt,1–4 Bruna Velasques,1–3,5 Silmar Teixeira,1,2,4 Luis F Basile,6,7 José Inácio Salles,5,8 Antonio Egídio Nardi,9 Henning Budde,10 Mauricio Cagy,11 Roberto Piedade,1 Pedro Ribeiro1,2,12 1Brain Mapping and Sensory Motor Integration Laboratory, Institute of Psychiatry, Federal University of Rio de Janeiro, 2Institute of Applied Neuroscience, Rio de Janeiro, 3Neurophysiology and Neuropsychology of Attention, Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, 4Laboratory of Physical Therapy, Veiga de Almeida University, Rio de Janeiro, 5Neuromuscular Research Laboratory, National Institute of Traumatology and Orthopaedics, Rio de Janeiro, 6Division of Neurosurgery, University of São Paulo Medical School, São Paulo, 7Laboratory of Psychophysiology, Department of Psychology and Phonoaudiology, Universidade Metodista do Estado de São Paulo (UMESP, São Paulo, 8Brazilian Volleyball Confederation, Rio de Janeiro, 9Panic and Respiration Laboratory, Federal University of Rio de Janeiro, Instituto Nacional de Ciência e Tecnologia (INCT e Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq, Rio de Janeiro, Brazil; 10Department of Sport Science and Physical Education, School of Science and Engineering, Reykjavik University, Reykjavik, Iceland; 11Biomedical Engineering Program, Coordenação dos Programas de Pós-Graduação em Engenharia (COPPE, Federal University of Rio de Janeiro, Rio de Janeiro; 12School of Physical Education, Bioscience Department Escola de Educação Física e Desportos da Universidade Federal do Rio de Janeiro (EEFD/UFRJ, Rio de Janeiro, Brazil Objective: The study presented here analyzed the patterns of relationship between oculomotor performance and psychopathology, focusing on depression, bipolar disorder, schizophrenia, attention-deficit hyperactivity disorder, and anxiety disorder. Methods: Scientific articles published from 1967 to 2013 in the Pub

  20. 77 FR 66484 - PSEG Nuclear LLC; Hope Creek Generating Station and Salem Generating Station, Units 1 and 2...

    Science.gov (United States)

    2012-11-05

    ... Power Plant Personnel,'' endorses the Nuclear Energy Institute (NEI) report, NEI 06-11, Revision 1... exclusion, set forth in 10 CFR 51.22(c)(25). Pursuant to 10 CFR 51.22(b), no environmental impact statement... Commission (NRC or the Commission) now or hereafter in effect. The facilities consist of one boiling-water...

  1. The Barrie Jones Lecture—Eye care for the neglected population: challenges and solutions

    Science.gov (United States)

    Rao, G N

    2015-01-01

    Globally, pockets of ‘neglected populations' do not have access to basic health-care services and carry a much greater risk of blindness and visual impairment. While large-scale public health approaches to control blindness due to vitamin A deficiency, onchocerciasis, and trachoma are successful, other causes of blindness still take a heavy toll in the population. High-quality comprehensive eye care that is equitable is the approach that needs wide-scale application to alleviate this inequity. L V Prasad Eye Institute of India developed a multi-tier pyramidal model of eye care delivery that encompasses all levels from primary to advanced tertiary (quaternary). This has demonstrated the feasibility of ‘Universal Eye Health Coverage' covering promotive, preventive, corrective, and rehabilitative aspects of eye care. Using human resources with competency-based training, effective and cost-effective care could be provided to many disadvantaged people. PMID:25567375

  2. 75 FR 54642 - National Eye Institute; Notice of Meeting

    Science.gov (United States)

    2010-09-08

    ... public as indicated below, with attendance limited to space available. Individuals who plan to attend and... disclose confidential trade secrets or commercial property such as patentable material, and personal... concerning Institute programs. Place: Melrose Hotel, 2430 Pennsylvania Ave., NW., Washington, DC 20037...

  3. Pseudoexfoliation syndrome at a Singapore eye clinic

    Directory of Open Access Journals (Sweden)

    Lee JK

    2015-09-01

    Full Text Available Jason Kian Seng Lee, Elizabeth Poh Ying Wong, Su Ling HoNational Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore Background: The purpose of this study was to investigate the demographics of pseudoexfoliation syndrome (PXF and pseudoexfoliative glaucoma (PXG in a Singapore hospital eye outpatient clinic.Methods: A retrospective study of 93 consecutive patients (146 eyes with PXF was undertaken by a single ophthalmologist over a period of 37 months (July 1, 2006, to July 31, 2009.Results: Ninety-three (2.8% of 3,297 patients seen during the study period were diagnosed with PXF. Forty-three (46.2% of the 93 PXF patients were male. Indians were 5.04 times more likely to develop PXF than Chinese (P<0.001, 95% confidence interval 3.05–8.33, while Malays were 2.22 times more likely to develop PXF as compared with Chinese (P=0.029, 95% CI 1.08–4.55. Twenty-two (23.7% of the 93 PXF patients had PXG at the time of diagnosis. There was no statistically significant difference in mean age between PXF and PXG patients. There was a larger proportion of males with PXG than females (P<0.001.Conclusion: PXF is not infrequent in elderly Singapore eye clinic patients, and is more likely to occur in Indians than in Chinese. In the Singapore eye clinic setting, males may be more likely to develop PXG, although larger studies will be required to confirm this.Keywords: exfoliation syndrome, pseudoexfoliation syndrome, exfoliation glaucoma, glaucoma capsulare

  4. EyeGENE

    Data.gov (United States)

    U.S. Department of Health & Human Services — The eyeGENE® Biorepository and corresponding Database contain family history and clinical eye exam data from subjects enrolled in eyeGENE® Program coupled to...

  5. Bags Under Eyes

    Science.gov (United States)

    Bags under eyes Overview Bags under eyes — mild swelling or puffiness under the eyes — are common as you age. With aging, the tissues around your ... space below your eyes, adding to the swelling. Bags under eyes are usually a cosmetic concern and ...

  6. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Español Eye Health / Eye Health A-Z Dry Eye Sections What Is Dry Eye? Dry Eye Symptoms ... Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué es el ojo seco? ...

  7. The Mozart effect in biofeedback visual rehabilitation: a case report.

    Science.gov (United States)

    Salvatore, Serena; Librando, Aloisa; Esposito, Mariacristina; Vingolo, Enzo M

    2011-01-01

    To evaluate the usefulness of acoustic biofeedback by means of Mozart's Sonata for Two Pianos in D Major K. 448 to maintain and/or restore visual performance in a patient with macular pucker and glaucoma. A 74-year-old patient with open angle glaucoma in both eyes and macular pucker in the right eye (RE) underwent visual rehabilitation with acoustic biofeedback by means of the MAIA™ Vision Training Module (Centervue, Padova, Italy) 10 minutes each eye once a week for 5 weeks. The patient was asked to move his eyes according to a sound which changed into Mozart's Sonata for Two Pianos when the patient locked the fixation target. Best-corrected visual acuity improved in his right eye (RE) and was stable in the left eye (LE). Fixation stability improved in both eyes, and retinal sensitivity decreased in the RE and improved in the LE. The characteristic of the macular pucker did not change during the training as demonstrated with optical coherence tomography. The patient was very satisfied with the training, as demonstrated by a 25-item questionnaire (National Eye Institute - Visual Functioning Questionnaire, NEI-VFQ-25). The patient's reading speed and the character size which he was able to read improved in his RE. Music could enhance synaptic plasticity and affect neural learning and fixation training by means of MAIA vision training. Therefore it can improve visual performance in patients with macular pucker, postpone the surgical time, and assure a better quality of life for the patient.

  8. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Stories Español Eye Health / Eye Health A-Z Dry Eye Sections What Is Dry Eye? Dry Eye Symptoms ... of Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué es el ojo seco? ...

  9. About the Eye

    Medline Plus

    Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun Stuff Cool Eye Tricks Links to More Information Optical Illusions Printables About the Eye Your eyes ...

  10. Eye movement control in reading unspaced text: the case of the Japanese script.

    Science.gov (United States)

    Kajii, N; Nazir, T A; Osaka, N

    2001-09-01

    The present study examines the landing-site distributions of the eyes during natural reading of Japanese script: a script that mixes three different writing systems (Kanji, Hiragana, and Katakana) and that misses regular spacing between words. The results show a clear preference of the eyes to land at the beginning rather than the center of the word. In addition, it was found that the eyes land on Kanji characters more frequently than on Hiragana or Katakana characters. Further analysis for two- and three-character words indicated that the eye's landing-site distribution differs depending on type of the characters in the word: the eyes prefer to land at the word beginning only when the initial character of the word is a Kanji character. For pure Hiragana words, the proportion of initial fixations did not differ between character positions. Thus, as already indicated by Kambe (National Institute of Japanese Language Report 85 (1986) 29), the visual distinctiveness of the three Japanese scripts plays a role in guiding eye movements in reading Japanese.

  11. Annual direct cost of dry eye in Japan

    Directory of Open Access Journals (Sweden)

    Mizuno Y

    2012-05-01

    Full Text Available Yoshinobu Mizuno, Masakazu Yamada, Chika ShigeyasuDivision for Vision Research, National Institute of Sensory Organs, National Tokyo Medical Center, Tokyo, JapanOn behalf of The Dry Eye Survey Group, National Hospital Organization of JapanBackground: This study was performed to estimate the annual direct cost incurred by dry eye patients, which includes expenses for treatment and drugs, as well as the cost of punctal plugs.Methods: The study group consisted of 118 dry eye patients aged 20 years or older who visited any of the 15 medical care facilities that participated in this prospective cohort dry eye study. We estimated annual direct costs from outpatient medical records and survey questionnaires obtained from patients. Results: Of the total patients enrolled, 10 were men and 108 women, and their average age was 64.1 ± 11.2 years. The number of hospital visits made by patients was 5.8 ± 3.6 per year. Among those who used ophthalmic solutions, the numbers of bottles used per year were as follows: 32.1 ± 20.8 bottles of hyaluronic acid ophthalmic solution (87 patients, 53.1 ± 42.2 bottles of artificial tears (40 patients, and 33.2 ± 23.2 bottles of over-the-counter eyedrops (15 patients. In patients with punctal plugs, 4.1 ± 3.9 plugs were used annually. The annual drug cost was 32,000 ± 21,675 Japanese yen (323 ± 219 US dollars. The clinical cost was 16,318 ± 9961 Japanese yen (165 ± 101 US dollars. The total direct costs including punctal plug treatment amounted to 52,467 ± 38,052 Japanese yen (530 ± 384 US dollars. Conclusion: Although treatment modalities for dry eye in Japan were different from those in the US and in European countries, the direct cost of dry eye patients in Japan was comparable with that reported in those countries. Considering the high prevalence of dry eye, the direct cost of this chronic condition may be significant.Keywords: burden of disease, cost, dry eye, eyedrops, quality of life

  12. Eye Movement Disorders

    Science.gov (United States)

    ... work properly. There are many kinds of eye movement disorders. Two common ones are Strabismus - a disorder ... in "crossed eyes" or "walleye." Nystagmus - fast, uncontrollable movements of the eyes, sometimes called "dancing eyes" Some ...

  13. Severe structural and functional visual system damage leads to profound loss of vision-related quality of life in patients with neuromyelitis optica spectrum disorders.

    Science.gov (United States)

    Schmidt, Felix; Zimmermann, Hanna; Mikolajczak, Janine; Oertel, Frederike C; Pache, Florence; Weinhold, Maria; Schinzel, Johann; Bellmann-Strobl, Judith; Ruprecht, Klemens; Paul, Friedemann; Brandt, Alexander U

    2017-01-01

    Neuromyelitis optica spectrum disorders (NMOSD) are characterized by devastating optic neuritis attacks causing more structural damage and visual impairment than in multiple sclerosis (MS). The objective of this study was to compare vision-related quality of life in NMOSD and MS patients and correlate it to structural retinal damage and visual function. Thirty-one NMOSD and 31 matched MS patients were included. Vision-related quality of life was assessed with the 39-item National Eye Institute Visual Function Questionnaire (NEI-VFQ). All patients underwent retinal optical coherence tomography and visual acuity and contrast sensitivity measurements. Vision-related quality of life was reduced in NMOSD compared to MS patients. This difference was driven by a higher incidence of bilateral and more severe optic neuritis in the NMOSD group. Retinal thinning and visual impairment were significantly greater in the NMOSD cohort. Lower vision-related quality of life was associated with more retinal damage and reduced visual function as assessed by visual acuity and contrast sensitivity. NMOSD-related bilateral ON-attacks cause severe structural damage and visual impairment that lead to severe loss of vision-related quality of life. The NEI-VFQ is a helpful tool to monitor vision-related quality of life in NMOSD patients. Copyright © 2016 Elsevier B.V. All rights reserved.

  14. Health-related quality of life following blind rehabilitation.

    Science.gov (United States)

    Kuyk, Thomas; Liu, Lei; Elliott, Jeffry L; Grubbs, Hartley E; Owsley, Cynthia; McGwin, Gerald; Griffin, Russell L; Fuhr, Patti S

    2008-05-01

    The purpose of this study was to investigate the effect of residential blind rehabilitation on patients' vision-targeted health-related quality of life (HRQOL) and general physical and mental function. The National Eye Institute 25-item Visual Function Questionnaire (NEI VFQ) plus appendix questions, the 12-item Short-Form Health Survey (SF-12), Hope Scale and Coopersmith self-esteem inventory were administered to 206 legally blind veterans prior to their entering a residential (in-patient) blind rehabilitation program and again to 185 and 176 of the original cohort at 2 and 6 months after completion of the rehabilitation program, respectively. Data on visual acuity, visual field extent, contrast sensitivity and scanning ability were also collected. The duration of the in-patient rehabilitation programs ranged from 11 to 109 days. Questionnaire scores were compared pre-rehabilitation and post-rehabilitation. Following rehabilitation there was a significant improvement in nine of 11 NEI VFQ subscales and in a composite score at both the 2- and 6-month post-rehabilitation intervals. Mental health (SF-12) and self esteem also improved significantly although physical health ratings declined over the course of the study (approximately 10 months). Residential blind rehabilitation appears to improve patients' self-reported vision-targeted HRQOL, self-esteem and mental health aspects of generic HRQOL.

  15. The interblink interval in normal and dry eye subjects

    Directory of Open Access Journals (Sweden)

    Johnston PR

    2013-02-01

    Full Text Available Patrick R Johnston,1 John Rodriguez,1 Keith J Lane,1 George Ousler,1 Mark B Abelson1,21Ora, Inc, Andover, MA, USA; 2Schepens Eye Research Institute and Harvard Medical School, Boston, MA, USAPurpose: Our aim was to extend the concept of blink patterns from average interblink interval (IBI to other aspects of the distribution of IBI. We hypothesized that this more comprehensive approach would better discriminate between normal and dry eye subjects.Methods: Blinks were captured over 10 minutes for ten normal and ten dry eye subjects while viewing a standardized televised documentary. Fifty-five blinks were analyzed for each of the 20 subjects. Means, standard deviations, and autocorrelation coefficients were calculated utilizing a single random effects model fit to all data points and a diagnostic model was subsequently fit to predict probability of a subject having dry eye based on these parameters.Results: Mean IBI was 5.97 seconds for normal versus 2.56 seconds for dry eye subjects (ratio: 2.33, P = 0.004. IBI variability was 1.56 times higher in normal subjects (P < 0.001, and the autocorrelation was 1.79 times higher in normal subjects (P = 0.044. With regard to the diagnostic power of these measures, mean IBI was the best dry eye versus normal classifier using receiver operating characteristics (0.85 area under curve (AUC, followed by the standard deviation (0.75 AUC, and lastly, the autocorrelation (0.63 AUC. All three predictors combined had an AUC of 0.89. Based on this analysis, cutoffs of ≤3.05 seconds for median IBI, and ≤0.73 for the coefficient of variation were chosen to classify dry eye subjects.Conclusion: (1 IBI was significantly shorter for dry eye patients performing a visual task compared to normals; (2 there was a greater variability of interblink intervals in normal subjects; and (3 these parameters were useful as diagnostic predictors of dry eye disease. The results of this pilot study merit investigation of IBI

  16. About the Eye

    Medline Plus

    Full Text Available ... for Kids >> About the Eye Listen All About Vision About the Eye Ask a Scientist Video Series ... Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes Fun ...

  17. About the Eye

    Medline Plus

    Full Text Available ... eye behind the iris that helps to focus light on the retina. It allows the eye to ... of the eye. It regulates the amount of light entering the eye through the pupil. Pupil (PYOO- ...

  18. Diabetic Eye Disease

    Science.gov (United States)

    ... Disease, & Other Dental Problems Diabetes & Sexual & Urologic Problems Diabetic Eye Disease What is diabetic eye disease? Diabetic eye disease is a group ... eye diseases that can threaten your sight are Diabetic retinopathy The retina is the inner lining at ...

  19. Updating OSHA Standards Based on National Consensus Standards; Eye and Face Protection. Final rule.

    Science.gov (United States)

    2016-03-25

    On March 13, 2015, OSHA published in the Federal Register a notice of proposed rulemaking (NPRM) to revise its eye and face protection standards for general industry, shipyard employment, marine terminals, longshoring, and construction by updating the references to national consensus standards approved by the American National Standards Institute (ANSI). OSHA received no significant objections from commenters and therefore is adopting the amendments as proposed. This final rule updates the references in OSHA's eye and face standards to reflect the most recent edition of the ANSI/International Safety Equipment Association (ISEA) eye and face protection standard. It removes the oldest-referenced edition of the same ANSI standard. It also amends other provisions of the construction eye and face protection standard to bring them into alignment with OSHA's general industry and maritime standards.

  20. What Is Dry Eye?

    Science.gov (United States)

    ... Eye? Dry Eye Symptoms Causes of Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué ... Inside of Your Eyelid Nov 29, 2017 New Dry Eye Treatment is a Tear-Jerker Jul 21, 2017 Three ...

  1. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Eye Health A-Z Symptoms Glasses & Contacts Tips & Prevention News Ask an Ophthalmologist Patient Stories Español Eye ... Eye Symptoms Causes of Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué ...

  2. 77 FR 8266 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-02-14

    ... interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus...

  3. 76 FR 2914 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2011-01-18

    ... interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus...

  4. 75 FR 57968 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2010-09-23

    ... interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus...

  5. 77 FR 55852 - National Eye Institute; Notice of Closed Meeting

    Science.gov (United States)

    2012-09-11

    ... interest of security, NIH has instituted stringent procedures for entrance onto the NIH campus. All visitor vehicles, including taxicabs, hotel, and airport shuttles will be inspected before being allowed on campus...

  6. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Eye? Dry Eye Symptoms Causes of Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué ... Inside of Your Eyelid Nov 29, 2017 New Dry Eye Treatment is a Tear-Jerker Jul 21, 2017 Three ...

  7. Presence or absence of ocular surface inflammation directs clinical and therapeutic management of dry eye

    OpenAIRE

    Sambursky, Robert

    2016-01-01

    Robert Sambursky Coastal Eye Institute, Cornea and Comprehensive Ophthalmology, Bradenton, FL, USA Background: The presence of clinically significant inflammation has been confirmed in the tears of 40%–65% of patients with symptoms of dry eye. Ocular surface inflammation may lead to tear film instability, epithelial cell irregularities, and permeability, resulting in chronic symptomatic pain and fluctuating vision as well as negative surgical outcomes.Patients and methods: A retro...

  8. Your Eyes

    Science.gov (United States)

    ... away? If you guessed the eye, you're right! Your eyes are at work from the moment you wake up to the ... the eye is seeing. A Muscle Makes It Work The lens is suspended in ... of the lens. That's right — the lens actually changes shape right inside your ...

  9. Greek mythology: the eye, ophthalmology, eye disease, and blindness.

    Science.gov (United States)

    Trompoukis, Constantinos; Kourkoutas, Dimitrios

    2007-06-01

    In distant eras, mythology was a form of expression used by many peoples. A study of the Greek myths reveals concealed medical knowledge, in many cases relating to the eye. An analysis was made of the ancient Greek texts for mythological references relating to an understanding of vision, visual abilities, the eye, its congenital and acquired abnormalities, blindness, and eye injuries and their treatment. The Homeric epics contain anatomical descriptions of the eyes and the orbits, and an elementary knowledge of physiology is also apparent. The concept of the visual field can be seen in the myth of Argos Panoptes. Many myths describe external eye disease ("knyzosis"), visual disorders (amaurosis), and cases of blinding that, depending on the story, are ascribed to various causes. In addition, ocular motility abnormalities, congenital anomalies (cyclopia), injuries, and special treatments, such as the "licking" method, are mentioned. The study of mythological references to the eye reveals reliable medical observations of the ancient Greeks, which are concealed within the myths.

  10. Impact of dry eye on work productivity

    OpenAIRE

    Yamada, Masakazu; Mizuno,Yoshinobu; Shigeyasu,Chika

    2012-01-01

    Masakazu Yamada, Yoshinobu Mizuno, Chika ShigeyasuNational Institute of Sensory Organs, National Hospital Organization Tokyo Medical Center, Tokyo, JapanBackground: The purpose of this study was to evaluate the impact of dry eye on work productivity of office workers, especially in terms of presenteeism.Methods: A total of 396 individuals aged ≥20 years (258 men and 138 women, mean age 43.4 ± 13.0 years) were recruited through an online survey. Data from 355 responders who d...

  11. Wavefront Derived Refraction and Full Eye Biometry in Pseudophakic Eyes.

    Directory of Open Access Journals (Sweden)

    Xinjie Mao

    Full Text Available To assess wavefront derived refraction and full eye biometry including ciliary muscle dimension and full eye axial geometry in pseudophakic eyes using spectral domain OCT equipped with a Shack-Hartmann wavefront sensor.Twenty-eight adult subjects (32 pseudophakic eyes having recently undergone cataract surgery were enrolled in this study. A custom system combining two optical coherence tomography systems with a Shack-Hartmann wavefront sensor was constructed to image and monitor changes in whole eye biometry, the ciliary muscle and ocular aberration in the pseudophakic eye. A Badal optical channel and a visual target aligning with the wavefront sensor were incorporated into the system for measuring the wavefront-derived refraction. The imaging acquisition was performed twice. The coefficients of repeatability (CoR and intraclass correlation coefficient (ICC were calculated.Images were acquired and processed successfully in all patients. No significant difference was detected between repeated measurements of ciliary muscle dimension, full-eye biometry or defocus aberration. The CoR of full-eye biometry ranged from 0.36% to 3.04% and the ICC ranged from 0.981 to 0.999. The CoR for ciliary muscle dimensions ranged from 12.2% to 41.6% and the ICC ranged from 0.767 to 0.919. The defocus aberrations of the two measurements were 0.443 ± 0.534 D and 0.447 ± 0.586 D and the ICC was 0.951.The combined system is capable of measuring full eye biometry and refraction with good repeatability. The system is suitable for future investigation of pseudoaccommodation in the pseudophakic eye.

  12. Quality of life at 6 months in the Idiopathic Intracranial Hypertension Treatment Trial.

    Science.gov (United States)

    Bruce, Beau B; Digre, Kathleen B; McDermott, Michael P; Schron, Eleanor B; Wall, Michael

    2016-11-01

    To examine the changes in vision-specific and overall health-related quality of life (QOL) at 6 months in participants with idiopathic intracranial hypertension (IIH) and mild visual loss enrolled in the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT) and to determine the signs and symptoms of IIH that mediate the effect of acetazolamide on QOL. We assessed QOL using the National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25), the 10-Item NEI-VFQ-25 Neuro-Ophthalmic Supplement, and the 36-Item Short Form Health Survey (SF-36). We examined associations among changes in QOL measures over 6 months, treatment status, and changes in signs and symptoms using linear and structural equation models. Among the 165 participants with IIH (86 randomized to acetazolamide, 79 to placebo), beneficial effects of acetazolamide were seen on all QOL scales evaluated, as well as on the Near Activities (5.60 points, p = 0.03), Social Functioning (3.85 points, p = 0.04), and Mental Health (9.82, p = 0.04) subscales of the NEI-VFQ-25. Positive acetazolamide-related effects on QOL appeared to be primarily mediated by improvements in visual field, neck pain, pulsatile tinnitus, and dizziness/vertigo that outweighed the side effects of acetazolamide. The marked reductions in baseline QOL seen among patients with mild visual loss from IIH are improved by treatment with acetazolamide. When combined with acetazolamide-associated improvements in visual field and other aspects of IIH, our findings with respect to QOL provide further support from the IIHTT in favor of acetazolamide to augment a dietary intervention in the treatment of IIH with mild visual loss (clinicaltrials.gov: NCT01003639). © 2016 American Academy of Neurology.

  13. Nanomedicine for glaucoma: liposomes provide sustained release of latanoprost in the eye

    Directory of Open Access Journals (Sweden)

    Natarajan JV

    2012-01-01

    Full Text Available Jayaganesh V Natarajan1*, Marcus Ang2*, Anastasia Darwitan1, Sujay Chattopadhyay3, Tina T Wong2, Subbu S Venkatraman1 1Materials Science and Engineering, Nanyang Technological University, Singapore; 2Singapore Eye Research Institute, Singapore; 3Polymer Division, Indian Institute of Technology Roorkee, India*These authors contributed equally to this workPurpose: To report the development and therapeutic evaluation of a liposomal nanocarrier for sustained release of latanoprost, in the rabbit eye.Methods: We fabricated latanoprost-loaded egg-phosphatidylcholine (EggPC liposomes using the film hydration technique. The delivery vehicles were nano-sized (Z avg = 109 ± 18 nm, had a narrow poly dispersity index (PDI = 0.19 ± 0.04, and a very high loading efficiency (94% ± 5%. Based on in vitro data, we evaluated this formulation for lowering intraocular pressure (IOP in rabbit eyes. Following a single subconjunctival injection of the latanoprost loaded formulation, the eyes were clinically monitored and the IOP recorded.Results: Latanoprost-loaded EggPC liposomes demonstrated a high drug/lipid mole ratio of 0.181, remained stable for at least 6 months on storage (4°C, and at least 1 month at 25°C. A slow and sustained release of 60% of latanoprost was achieved by 14 days in the in vitro release study. The same formulation demonstrated a greater sustained IOP lowering effect compared with daily administration of topical latanoprost beyond 90 days (4.8 ± 1.5 vs 2.5 ± 0.9 mmHg; P < 0.001. No signs of inflammation were evident in the eyes from slit-lamp examination analysis.Conclusion: The loading required for a long-term sustained delivery of latanoprost for up to 90 days in the rabbit eyes was achieved with EggPC liposomes. A single injection of latanoprost-loaded EggPC liposomes can lower the IOP for up to 90 days, with a greater IOP lowering effect than daily topical administration of latanoprost.Keywords: nanomedicine, nanoliposomes, Egg

  14. Eye Irritation Test of Bovis Calculus Pharmacopuncture Solutions for Eye Drop

    Directory of Open Access Journals (Sweden)

    Hyeong-sik Seo

    2008-06-01

    Full Text Available Objective : This study was done to investigate the safety of Bovis Calculus pharmacopuncture solution manufactured with freezing dryness method to use eye drop. Methods : The eye irritation test of this material was performed according to the Regulation of Korea Food & Drug Administration (2005. 10. 21, KFDA 2005-60. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, the auther observed eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Results : 1. After Bovis Calculus pharmacopuncture solution was medicated in the left eye of the rabbits, there wasn’t physical problem at 9 rabbits. 2. After Bovis Calculus pharmacopuncture solutionwas medicated in the left eye of the rabbits, there wasn’t eye irritation of the cornea, iris, conjunctiva at 1, 2, 3, 4 & 7day. Conclusions : I suggested that Bovis Calculus pharmacopuncture solution didn’t induced eye irritation in rabbits.

  15. The role of eye protection in work-related eye injuries.

    Science.gov (United States)

    Fong, L P; Taouk, Y

    1995-05-01

    A recent survey of general hospitals by the Victorian Injury Surveillance System found that ocular trauma represented 15% of work-related injuries. As circumstances surrounding occupational eye injuries have been poorly documented previously, their associations to occupation, industry and work-safety practices, including safety eyewear use, need to be identified to develop appropriate preventive strategies for high-risk groups. From a prospective cross-sectional survey of all eye injuries treated at the Royal Victorian Eye and Ear Hospital, work-related cases were analysed for demographic, occupational and safety eye-wear information. Hospital-based data were supplemented by information from WorkCover Authorities and Labour Force statistics to derive incidence and cost estimates. There were 9390 eye injuries during the 18-month survey period; 42% (n=3923) of total and 29% (n=52) of penetrating ocular injuries occurred at work. The most frequently injured were metal, automotive and building trades workers grinding and drilling (41% of outpatients) and hammering (53% of penetrating eye injuries). Automotive workers had the highest frequency for penetrating injuries, and most were exposed to hammering and were also the least likely to wear safety eye-wear. Eye injuries are frequent (10% of work-related injuries) and highly preventable by the correct use of safety eye-wear, a cost-effective intervention that may result in cost savings of $59 million for work-type activities in the occupational and domestic settings in Australia each year.

  16. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Eye Symptoms Causes of Dry Eye Dry Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué ... Your Eyelid Nov 29, 2017 New Dry Eye Treatment is a Tear-Jerker Jul 21, 2017 Three ...

  17. Paired-eye comparison of medical therapies for glaucoma

    Directory of Open Access Journals (Sweden)

    Alfred M Solish

    2010-09-01

    Full Text Available Alfred M Solish1,2, Friedericke James1, John G Walt3, Tina H Chiang31Southern California Glaucoma Consultants, Pasadena CA, USA; 2Jules Stein Eye Institute, University of California Los Angeles, Los Angeles, 3Allergan Inc., Irvine, CA, USA Objective: To evaluate efficacy and patient preference retrospectively among intraocular pressure (IOP-lowering prostamide and prostaglandin medications in a real-world clinical setting.Methods: Chart review of patients with uncontrolled glaucoma or ocular hypertension seen at a private practice clinic (n = 55 who received bimatoprost 0.03% once daily in one eye and either travoprost 0.004% or latanoprost 0.005% once daily in the fellow eye. IOP was evaluated at the initial visit and at a follow-up visit scheduled 4–6 weeks later. At the follow-up visit, each patient discussed the clinical results with their physician, chose which medication they preferred to continue using, and were queried regarding the reason for their choice. This paired-eye comparison method is used routinely in clinical practice to assess clinical response and involve patients in decisions regarding treatment. Change in mean IOP from baseline and patient medication choice were the outcome measures.Results: Bimatoprost-treated eyes (n = 52 had a mean IOP reduction of 2.7 mmHg and travoprost-treated eyes (n = 47 had an average decrease of 1.7 mmHg (P = 0.230. Bimatoprost significantly reduced mean IOP (from 19.8 mmHg at baseline to 17.1 mmHg at follow-up, P < 0.0001, as did travoprost (from 19.4 mmHg at baseline to 17.7 mmHg at follow-up, P = 0.009. Latanoprost-treated eyes were excluded from the efficacy analysis due to small sample size (n = 5. For continued therapy, patients chose bimatoprost over travoprost by a factor of 2.4 to 1. Of the 15 patients who gave a reason for their choice, 80% said their decision was based primarily on IOP change.Conclusions: Bimatoprost and travoprost were efficacious in reducing IOP among patients with

  18. EYE GAZE TRACKING

    DEFF Research Database (Denmark)

    2017-01-01

    This invention relates to a method of performing eye gaze tracking of at least one eye of a user, by determining the position of the center of the eye, said method comprising the steps of: detecting the position of at least three reflections on said eye, transforming said positions to spanning...... a normalized coordinate system spanning a frame of reference, wherein said transformation is performed based on a bilinear transformation or a non linear transformation e.g. a möbius transformation or a homographic transformation, detecting the position of said center of the eye relative to the position...... of said reflections and transforming this position to said normalized coordinate system, tracking the eye gaze by tracking the movement of said eye in said normalized coordinate system. Thereby calibration of a camera, such as knowledge of the exact position and zoom level of the camera, is avoided...

  19. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Tips & Prevention News Ask an Ophthalmologist Patient Stories Español Eye Health / Eye Health A-Z Dry Eye ... Eye Treatment What Is Dry Eye? Leer en Español: ¿Qué es el ojo seco? Written By: Kierstan ...

  20. Does reproduction accelerate the growth of eye lens mass in female voles?

    Czech Academy of Sciences Publication Activity Database

    Jánová, Eva; Havelková, Dana; Tkadlec, Emil

    2007-01-01

    Roč. 137, č. 1 (2007), s. 85-88 ISSN 0777-6276 R&D Projects: GA ČR GA206/04/2003; GA ČR(CZ) GD524/05/H536 Institutional research plan: CEZ:AV0Z60930519 Keywords : age estimation * eye lens mass * reproduction Subject RIV: EH - Ecology, Behaviour Impact factor: 0.433, year: 2007 http://www.naturalsciences.be/institute/associations/rbzs_website/bjz/back/pdf/BJZ%20137(1)/Volume%20137(1),%20pp.%2085-88.pdf

  1. Dry eyes : a commonly missed eye condition

    OpenAIRE

    Vella, Mario;

    2014-01-01

    Tears are an important component in providing moisture and lubrication for the eyes, thereby maintaining vision and comfort. Dry eyes (keratoconjunctivitis sicca) result when there is either decreased production of tears or by poor tear quality which in turn lead to more rapid evaporation.

  2. Eye Tracker Accuracy: Quantitative Evaluation of the Invisible Eye Center Location

    OpenAIRE

    Wyder, Stephan; Cattin, Philippe C.

    2017-01-01

    Purpose. We present a new method to evaluate the accuracy of an eye tracker based eye localization system. Measuring the accuracy of an eye tracker's primary intention, the estimated point of gaze, is usually done with volunteers and a set of fixation points used as ground truth. However, verifying the accuracy of the location estimate of a volunteer's eye center in 3D space is not easily possible. This is because the eye center is an intangible point hidden by the iris. Methods. We evaluate ...

  3. Efficacy of topical cyclosporine 0.05% eye drops in the treatment of dry eyes

    OpenAIRE

    Haitham Y Al-Nashar

    2015-01-01

    Purpose The aim of the present study was to evaluate the effectiveness of cyclosporine 0.05% in the treatment of dry-eye disease. Patients and methods A total of 35 eyes of 20 patients with dry-eye disease were included in the present study. Ten patients (20 eyes) had dry eyes associated with systemic rheumatologic disease (Sjögren′s syndrome), five patients (10 eyes) had dry eyes after undergoing laser in-situ keratomileusis, and five patients (five eyes) had dry eyes after cataract...

  4. Premotor neurons encode torsional eye velocity during smooth-pursuit eye movements

    Science.gov (United States)

    Angelaki, Dora E.; Dickman, J. David

    2003-01-01

    Responses to horizontal and vertical ocular pursuit and head and body rotation in multiple planes were recorded in eye movement-sensitive neurons in the rostral vestibular nuclei (VN) of two rhesus monkeys. When tested during pursuit through primary eye position, the majority of the cells preferred either horizontal or vertical target motion. During pursuit of targets that moved horizontally at different vertical eccentricities or vertically at different horizontal eccentricities, eye angular velocity has been shown to include a torsional component the amplitude of which is proportional to half the gaze angle ("half-angle rule" of Listing's law). Approximately half of the neurons, the majority of which were characterized as "vertical" during pursuit through primary position, exhibited significant changes in their response gain and/or phase as a function of gaze eccentricity during pursuit, as if they were also sensitive to torsional eye velocity. Multiple linear regression analysis revealed a significant contribution of torsional eye movement sensitivity to the responsiveness of the cells. These findings suggest that many VN neurons encode three-dimensional angular velocity, rather than the two-dimensional derivative of eye position, during smooth-pursuit eye movements. Although no clear clustering of pursuit preferred-direction vectors along the semicircular canal axes was observed, the sensitivity of VN neurons to torsional eye movements might reflect a preservation of similar premotor coding of visual and vestibular-driven slow eye movements for both lateral-eyed and foveate species.

  5. Burning Eye Syndrome: Do Neuropathic Pain Mechanisms Underlie Chronic Dry Eye?

    Science.gov (United States)

    Kalangara, Jerry P; Galor, Anat; Levitt, Roy C; Felix, Elizabeth R; Alegret, Ramon; Sarantopoulos, Constantine D

    2016-04-01

    Dry eye is a multi-factorial disorder that manifests with painful ocular symptoms and visual disturbances, which can only be partly attributed to tear dysfunction. This disorder may also involve neuroplasticity in response to neuronal injury. This review will emphasize the key characteristics of dry eye pain and its pathologic mechanisms, making the argument that a subset of dry eye represents a neuropathic pain disorder of the eye, more appropriately called "burning eye syndrome." A literature review was conducted using a PubMed search focusing on dry eye, corneal nociception, and neuropathic pain. Articles were reviewed and those discussing clinical course, pathophysiology, and neuronal regulation of chronic ocular pain as related to dry eye were summarized. We found that there is a discordance between ocular pain and dryness on the ocular surface. Although tear dysfunction may be one of the initial insults, its persistence may be associated with repeated ocular sensory nerve injury leading to an acute-to-chronic pain transition associated with neuropathologic changes (peripheral and central sensitization), neuronal dysfunction, and spontaneous ocular pain. Dry eye is becoming a major health concern due to its increasing incidence, significant morbidity, and economic burden. Recent evidence suggests that a subset of dry eye may be better represented as a chronic neuropathic pain disorder due to its features of dysesthesia, spontaneous pain, allodynia, and hyperalgesia. Future therapies targeted at the underlying neuroplasticity may yield improved efficacy for patients with this subset of dry eye, which we term "burning eye syndrome." © 2015 American Academy of Pain Medicine. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  6. Fluorescein eye stain

    Science.gov (United States)

    Abnormal results may point to: Abnormal tear production (dry eye) Blocked tear duct Corneal abrasion (a scratch on ... object in eye ) Infection Injury or trauma Severe dry eye associated with arthritis (keratoconjunctivitis sicca)

  7. Effects of Punctal Occlusion on Clinical Signs and Symptoms and on Tear Cytokine Levels in Patients with Dry Eye.

    Science.gov (United States)

    Tong, Louis; Beuerman, Roger; Simonyi, Susan; Hollander, David A; Stern, Michael E

    2016-04-01

    To investigate changes in signs, symptoms, and tear cytokines following punctal plug occlusion in patients with dry eye. A single-center study was conducted at Singapore Eye Research Institute. Nonabsorbable punctal plugs were inserted in the lower punctum of both eyes in patients with moderate dry eye. Over 3 weeks, in the more severe eye, dry eye symptoms, fluorescein corneal staining, Schirmer I (without topical anesthesia) test, tear film breakup time (TFBUT), and safety were assessed. Cytokine and matrix metalloproteinase-9 (MMP-9) levels in tear samples were measured. Twenty-nine patients (mean age 49.8 years) with moderate dry eye were evaluated. At baseline, mean (standard deviation) global symptoms score was 53.8 (26.5), Schirmer I test score was 5.1 (2.8) mm, and TFBUT was 2.2 (0.6) seconds. After 3 weeks, punctal occlusion significantly reduced global irritation symptoms score (Pdry eye disease. Copyright © 2016 The Authors. Published by Elsevier Inc. All rights reserved.

  8. A scalable and deformable stylized model of the adult human eye for radiation dose assessment.

    Science.gov (United States)

    El Basha, Daniel; Furuta, Takuya; Iyer, Siva S R; Bolch, Wesley E

    2018-03-23

    With recent changes in the recommended annual limit on eye lens exposures to ionizing radiation, there is considerable interest in predictive computational dosimetry models of the human eye and its various ocular structures including the crystalline lens, ciliary body, cornea, retina, optic nerve, and central retinal artery. Computational eye models to date have been constructed as stylized models, high-resolution voxel models, and polygon mesh models. Their common feature, however, is that they are typically constructed of nominal size and of a roughly spherical shape associated with the emmetropic eye. In this study, we present a geometric eye model that is both scalable (allowing for changes in eye size) and deformable (allowing for changes in eye shape), and that is suitable for use in radiation transport studies of ocular exposures and radiation treatments of eye disease. The model allows continuous and variable changes in eye size (axial lengths from 20 to 26 mm) and eye shape (diopters from -12 to +6). As an explanatory example of its use, five models (emmetropic eyes of small, average, and large size, as well as average size eyes of -12D and +6D) were constructed and subjected to normally incident beams of monoenergetic electrons and photons, with resultant energy-dependent dose coefficients presented for both anterior and posterior eye structures. Electron dose coefficients were found to vary with changes to both eye size and shape for the posterior eye structures, while their values for the eye crystalline lens were found to be sensitive to changes in only eye size. No dependence upon eye size or eye shape was found for photon dose coefficients at energies below 2 MeV. Future applications of the model can include more extensive tabulations of dose coefficients to all ocular structures (not only the lens) as a function of eye size and shape, as well as the assessment of x-ray therapies for ocular disease for patients with non-emmetropic eyes. © 2018

  9. Glaucoma: Eye-to-Eye with Dr. Rachel Bishop

    Science.gov (United States)

    ... of this page please turn JavaScript on. Feature: Glaucoma Eye-to-Eye with Dr. Rachel Bishop Past ... nerves are pale and cupped—signs of advanced glaucoma. Yet the patient wasn't aware of any ...

  10. Using an eye tracker for accurate eye movement artifact correction

    NARCIS (Netherlands)

    Kierkels, J.J.M.; Riani, J.; Bergmans, J.W.M.; Boxtel, van G.J.M.

    2007-01-01

    We present a new method to correct eye movement artifacts in electroencephalogram (EEG) data. By using an eye tracker, whose data cannot be corrupted by any electrophysiological signals, an accurate method for correction is developed. The eye-tracker data is used in a Kalman filter to estimate which

  11. Tribal Odisha Eye Disease Study (TOES # 2 Rayagada school screening program: efficacy of multistage screening of school teachers in detection of impaired vision and other ocular anomalies

    Directory of Open Access Journals (Sweden)

    Panda L

    2018-06-01

    Full Text Available Lapam Panda,1 Taraprasad Das,1 Suryasmita Nayak,1 Umasankar Barik,2 Bikash C Mohanta,1 Jachin Williams,3 Vivekanand Warkad,4 Guha Poonam Tapas Kumar,5 Rohit C Khanna3 1Indian Oil Center for Rural Eye Health, GPR ICARE, L V Prasad Eye Institute, MTC Campus, Bhubaneswar, India; 2Naraindas Morbai Budhrani Eye Centre, L V Prasad Eye Institute, Rayagada, India; 3Gullapalli Pratibha Rao International Center for Advancement of Rural Eye Care, L V Prasad Eye Institute, KAR Campus, Hyderabad, India; 4Miriam Hyman Children Eye Care Center, L V Prasad Eye Institute, MTC Campus, Bhubaneswar, India; 5District Administration, Government of Odisha, Rayagada, India Purpose: To describe program planning and effectiveness of multistage school eye screening and assess accuracy of teachers in vision screening and detection of other ocular anomalies in Rayagada District School Sight Program, Odisha, India.Methods: This multistage screening of students included as follows: stage I: screening for vision and other ocular anomalies by school teachers in the school; stage II: photorefraction, subjective correction and other ocular anomaly confirmation by optometrists in the school; stage III: comprehensive ophthalmologist examination in secondary eye center; and stage IV: pediatric ophthalmologist examination in tertiary eye center. Sensitivity, specificity, positive predictive value (PPV and negative predictive value (NPV of teachers for vision screening and other ocular anomaly detection were calculated vis-à-vis optometrist (gold standard.Results: In the study, 216 teachers examined 153,107 (95.7% of enrolled students aged 5–15 years. Teachers referred 8,363 (5.4% of examined students and 5,990 (71.6% of referred were examined in stage II. After prescribing spectacles to 443, optometrists referred 883 students to stage III. The sensitivity (80.51% and PPV (93.05% of teachers for vision screening were high, but specificity (53.29% and NPV (26.02% were low. The

  12. About the Eye

    Medline Plus

    Full Text Available ... Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid Tips Healthy Vision ... to More Information Optical Illusions Printables About the Eye Your eyes are made up of many different ...

  13. About the Eye

    Medline Plus

    Full Text Available ... your eye. It helps your eye focus light so things look sharp and clear. Sclera (SKLEH-ruh) ... the different parts of your eye work together so you can see and make sense of the ...

  14. Use of preservative-free hyaluronic acid (Hylabak® for a range of patients with dry eye syndrome: experience in Russia

    Directory of Open Access Journals (Sweden)

    Brzhesky VV

    2014-06-01

    Full Text Available Vladimir Vsevolodovich Brjesky,1 Yury Fedorovich Maychuk,2 Alexey Vladimirovich Petrayevsky,3 Peter Gerrievich Nagorsky41Department of Ophthalmology, Pediatric State Medical Academy, Saint Petersburg, 2Moscow Research Institute of Eye Diseases, Moscow, 3Department of Ophthalmology, Volgograd State Medical University, Volgograd, 4Novosibirsk Branch of the Federal State Institute MNTK Eye Microsurgery, Novosibirsk, Russian Federation, RussiaAbstract: Artificial tear preparations are important in the management of dry eye syndrome. We present the findings from four recently published studies conducted in Russia assessing Hylabak® (marketed as Hyabak® in Europe, a preservative-free hyaluronic acid preparation, for the treatment of dry eye syndrome. All studies had an open, noncomparative design, but one compared the findings with those from 25 patients treated with Tear Naturale® in previous studies. A total of 134 children and adults were enrolled, and the etiologies of dry eye syndrome included contact lens use, intensive office work, adenovirus eye infection, postmenopausal status, persistent meibomian blepharitis, Sjögren's syndrome, phacoemulsification with intraocular lens implantation, and refractive surgery. The patients were treated with Hylabak for 2 weeks to 2 months. All studies showed that Hylabak resulted in marked improvement as assessed by subjective sensations/complaints, Schirmer's test, Norn’s test, impression cytology and biomicroscopy, staining, and tear osmolarity. Greater benefits were also reported compared with Tear Naturale, including a faster onset of action. Hylabak was well tolerated. In conclusion, Hylabak provided rapid and safe relief from the signs and symptoms of dry eye syndrome, as well as improvement in objective measures, in a wide range of patients.Keywords: dry eye, eye drops, artificial tears, hyaluronic acid, Hylabak®, preservative-free

  15. Eye absence does not regulate planarian stem cells during eye regeneration

    OpenAIRE

    LoCascio, Samuel A.; Lapan, Sylvain W.; Reddien, Peter W.

    2017-01-01

    Dividing cells called neoblasts contain pluripotent stem cells and drive planarian flatworm regeneration from diverse injuries. A long-standing question is whether neoblasts directly sense and respond to the identity of missing tissues during regeneration. We used the eye to investigate this question. Surprisingly, eye removal was neither sufficient nor necessary for neoblasts to increase eye progenitor production. Neoblasts normally increase eye progenitor production following decapitation, ...

  16. Consistency of eye movements in MOT using horizontally flipped trials

    Czech Academy of Sciences Publication Activity Database

    Děchtěrenko, F.; Lukavský, Jiří

    2013-01-01

    Roč. 42, Suppl (2013), s. 42-42 ISSN 0301-0066. [36th European Conference on Visual Perception. 25.08.2013.-29.08.2013, Brémy] R&D Projects: GA ČR GA13-28709S Institutional support: RVO:68081740 Keywords : eye movements * symmetry * consistency Subject RIV: AN - Psychology http://www.ecvp.uni-bremen.de/~ecvpprog/abstract164.html

  17. About the Eye

    Medline Plus

    Full Text Available ... other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health ... Eye Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and ...

  18. Valutazione del carico di stress nei Vigili del Fuoco: correlazione con il profilo psicologico ed alcuni indicatori biologici di rischio

    Directory of Open Access Journals (Sweden)

    P. Giacobazzi

    2003-05-01

    Full Text Available

    Obiettivo: approfondire i rapporti tra carico lavorativo, personalità ed alcuni indicatori biochimici di risposta allo stress le cui modificazioni possono contribuire a spiegare la suscettibilità/resistenza al rischio di malattie.

     Materiali e metodi: l’indagine è stata effettuata su un gruppo di Vigili del Fuoco (n°61 confrontati con un gruppo di controllo (ricercatori universitari; entrambi hanno aderito tramite consenso informato e fornito un campione di saliva per la misura del cortisolo e delle IgA in condizioni di base. Un sottogruppo di vigili ha fornito anche un campione di saliva dopo un turno lavorativo notturno (condizione di stress. Parallelamente si è effettuato un assessment psicologico tramite la somministrazione di questionari quali: lo State-Trait Anxiety Inventory, il Big Five Observer, il Locus of Control ed il Sensation Seeking Scale. Risultati: in condizioni basali i Vigili del Fuoco mostrano un livello di cortisolo salivare più elevato dei controlli (24,9 ± 11,3 vs 20,0 ± 8,6 nmol/l, p=0,091, mentre il livello di IgA è simile nei due gruppi. Nei vigili, dopo lo stress lavorativo, si è evidenziato un calo significativo delle IgA (296,5 ± 160,5 vs 191,9 ± 95,3 Bg/ml, p=0,014 ed una correlazione positiva tra il cortisolo salivare e l’ansietà di stato e di tratto.

    Conclusioni: i Vigili del Fuoco sono risultati meno ansiosi, più predisposti al rischio e con un profilo di personalità di tipo realistico in linea con la scelta professionale. Lo stress lavorativo si associa ad una riduzione significativa dell’ escrezione salivare di IgA, assunta come indice di attività del sistema immunitario, mentre il cortisolo salivare, che rappresenta un indicatore sensibile di attività neuroendocrina sotto stress, pur non modificandosi in termini assoluti si associa con il livello di ansietà dei vigili allo studio.

  19. Why Do Eyes Water?

    Science.gov (United States)

    ... for Educators Search English Español Why Do Eyes Water? KidsHealth / For Kids / Why Do Eyes Water? What's ... coming out of your nose. Why Do Eyes Water? Eyes water for lots of different reasons besides ...

  20. Perceptions of Eye Health and Eye Health Services among Adults Attending Outreach Eye Care Clinics in Papua New Guinea.

    Science.gov (United States)

    Burnett, Anthea; Yu, Mitasha; Paudel, Prakash; Naduvilath, Thomas; Fricke, Tim R; Hani, Yvonne; Garap, Jambi

    2015-01-01

    To determine how people attending outreach eye care clinics in Papua New Guinea (PNG) perceive eye health and eye health services. An interview-based questionnaire was administrated to a convenience sample of 614 adult participants across four provinces and perceptions of eye health and eye health services were recorded. Presenting and near visual acuity were measured and cause of visual impairment (VI) determined. In this sample, 113/614 participants (18.4%) presented with distance VI, 16 (2.6%) with distance blindness, and 221 (47.6%) with near VI. Older participants and those with near VI were more likely to indicate that it is hard to have an eye examination due to travel time, lack of transport and transport costs. Female participants and those from underserved areas were more likely to report shame and fear of jealousy from others when asked about their attitudes towards spectacles. Participants reporting that they were willing to pay higher amounts for testing and spectacles/treatment also reported higher education levels, higher household incomes and were more likely to be male. A quarter of participants (25.9%) indicated that they did not like having an eye examination because their reading and writing was poor. People attending outreach eye care clinics in PNG reported finding it difficult to attend eye health services due to transport difficulties and anticipated high costs. Negative attitudes towards spectacles were also prevalent, and negative perceptions appeared more frequently among older participants and those with less education.

  1. Black Eye

    Science.gov (United States)

    ... Your Eyes Sep 20, 2017 Eye Injuries from Laundry Packets On the Rise Jun 30, 2017 ... Medical Disclaimer Privacy Policy Terms of Service For Advertisers For Media Ophthalmology Job Center © American ...

  2. A Clinical Study of Subtype-based Prevalence of Dry Eye.

    Science.gov (United States)

    Rege, Aditya; Kulkarni, Varsha; Puthran, Neelam; Khandgave, Tejaswini

    2013-10-01

    Dry Eye is a multifactorial disease of the tearfilm and the ocular surface which may be due to reduced tear production or excessive tear evaporation resulting in discomfort, visual disturbance, and tear film instability with a potential damage to the ocular surface. Various population-based studies have been done to find out the prevalence and the magnitude of the problem. Women Health Study reported prevalence of 7.8% after screening 36995 subjects above 49 years by interview. The prevalence reported by Blue Mountain Study was 15.3% .The Beaver Dam Study and Shiphai Eye studies are other studies reporting prevalence of 14.5% and 33.7% respectively. McMonnies questionnaire is a widely used screening instrument for Dry-Eye syndromes with sensitivity reportedly varying between 87% and 98% and specificity between 87% and 97%. Prevalence studies use McMonnie's questionnaire for screening individuals for Dry Eye, whereafter tests like Schirmer's test, Tear Film Break Up Time test, Rose Bengal test, Lissamine Green test and Meibomian Gland Dysfunction test are useful for further evaluation. While these tests help to differentiate the subtypes of Dry Eye such as Lipid Anomaly Dry Eye, Aqueous Tear Deficiency and Mucin Layer Deficiency, however, their sensitivity and specificity has not been widely studied. Additionally, very few studies have reported the prevalence of the various subtypes of Dry Eye. To determine the subtype-based prevalence of Dry Eye, to study the specificity and sensitivity of clinical tests for Dry Eye and to correlate McMonnies questionnaire with Dry Eye tests results. A prospective, cross-sectional, observational study, duly approved by the Institutional Ethics Committee, was conducted from October 2010 to April 2012. A total of 4750 subjects above 18 yrs of age were screened by the McMonnies questionnaire. Respondents having a score greater than 14.5 were subjected to clinical Dry Eye tests. The data obtained was analyzed using chi-square test. p

  3. Fish eye optics

    Science.gov (United States)

    Hudec, R.; Michalova, S.

    2017-07-01

    We report on small student (high—school) project of the Czech Academy of Sciences dealing with animal (fish) eyes and possible application in science and technology. Albeit most fishes have refractive eyes, the recent discoveries confirm that some fishes have reflective eyes with strange arrangements as well.

  4. The eye amputated - consequences of eye amputation with emphasis on clinical aspects, phantom eye syndrome and quality of life

    DEFF Research Database (Denmark)

    Rasmussen, Marie Louise Roed

    2010-01-01

    In this thesis the term eye amputation (EA) covers the removing of an eye by: evisceration, enucleation and exenteration. Amputation of an eye is most frequently the end-stage in a complicated disease, or the primary treatment in trauma and neoplasm. In 2010 the literature is extensive due...... to knowledge about types of surgery, implants and surgical technique. However, not much is known about the time past surgery. THE PURPOSE OF THE PHD THESIS WAS: To identify the number of EA, the causative diagnosis and the indication for surgical removal of the eye, the chosen surgical technique...... and to evaluate a possible change in surgical technique in Denmark from 1996 until 2003 (paper I); To describe the phantom eye syndrome and its prevalence of visual hallucinations, phantom pain and phantom sensations (paper II); To characterise the quality of phantom eye pain, including its intensity...

  5. Design, Sensing and Control of a Robotic Prosthetic Eye for Natural Eye Movement

    Directory of Open Access Journals (Sweden)

    J. J. Gu

    2006-01-01

    Full Text Available Loss of an eye is a tragedy for a person, who may suffer psychologically and physically. This paper is concerned with the design, sensing and control of a robotic prosthetic eye that moves horizontally in synchronization with the movement of the natural eye. Two generations of robotic prosthetic eye models have been developed. The first generation model uses an external infrared sensor array mounted on the frame of a pair of eyeglasses to detect the natural eye movement and to feed the control system to drive the artificial eye to move with the natural eye. The second generation model removes the impractical usage of the eye glass frame and uses the human brain EOG (electro-ocular-graph signal picked up by electrodes placed on the sides of a person's temple to carry out the same eye movement detection and control tasks as mentioned above. Theoretical issues on sensor failure detection and recovery, and signal processing techniques used in sensor data fusion, are studied using statistical methods and artificial neural network based techniques. In addition, practical control system design and implementation using micro-controllers are studied and implemented to carry out the natural eye movement detection and artificial robotic eye control tasks. Simulation and experimental studies are performed, and the results are included to demonstrate the effectiveness of the research project reported in this paper.

  6. Eye Anatomy

    Science.gov (United States)

    ... News About Us Donate In This Section Eye Anatomy en Español email Send this article to a ... You at Risk For Glaucoma? Childhood Glaucoma Eye Anatomy Five Common Glaucoma Tests Glaucoma Facts and Stats ...

  7. Eye Emergencies

    Science.gov (United States)

    ... The Marfan Foundation Marfan & Related Disorders What is Marfan Syndrome? What are Related Disorders? What are the Signs? ... Emergencies Eye Emergencies Lung Emergencies Surgeries Eye Emergencies Marfan syndrome significantly increases your risk of retinal detachment, a ...

  8. Persistent visual impairment in multiple sclerosis: prevalence, mechanisms and resulting disability.

    Science.gov (United States)

    Jasse, Laurence; Vukusic, Sandra; Durand-Dubief, Françoise; Vartin, Cristina; Piras, Carolina; Bernard, Martine; Pélisson, Denis; Confavreux, Christian; Vighetto, Alain; Tilikete, Caroline

    2013-10-01

    The objective of this article is to evaluate in multiple sclerosis (MS) patients the prevalence of persistent complaints of visual disturbances and the mechanisms and resulting functional disability of persistent visual complaints (PVCs). Firstly, the prevalence of PVCs was calculated in 303 MS patients. MS-related data of patients with or without PVCs were compared. Secondly, 70 patients with PVCs performed an extensive neuro-ophthalmologic assessment and a vision-related quality of life questionnaire, the National Eye Institute Visual Functionary Questionnaire (NEI-VFQ-25). PVCs were reported in 105 MS patients (34.6%). Patients with PVCs had more frequently primary progressive MS (30.5% vs 13.6%) and more neuro-ophthalmologic relapses (1.97 vs 1.36) than patients without PVCs. In the mechanisms/disability study, an afferent visual and an ocular-motor pathways dysfunction were respectively diagnosed in 41 and 59 patients, mostly related to bilateral optic neuropathy and bilateral internuclear ophthalmoplegia. The NEI-VFQ 25 score was poor and significantly correlated with the number of impaired neuro-ophthalmologic tests. Our study emphasizes the high prevalence of PVC in MS patients. Regarding the nature of neuro-ophthalmologic deficit, our results suggest that persistent optic neuropathy, as part of the progressive evolution of the disease, is not rare. We also demonstrate that isolated ocular motor dysfunctions induce visual disability in daily life.

  9. Eye evolution: lens and cornea as an upgrade of animal visual system

    Czech Academy of Sciences Publication Activity Database

    Jonášová, Kristýna; Kozmik, Zbyněk

    2008-01-01

    Roč. 19, č. 2 (2008), s. 71-81 ISSN 1084-9521 R&D Projects: GA AV ČR IAA500520604; GA MŠk(CZ) 1M0520 Institutional research plan: CEZ:AV0Z50520514 Keywords : eye * lens * cornea Subject RIV: EB - Genetics ; Molecular Biology Impact factor: 4.528, year: 2008

  10. A HOSPITAL-BASED STUDY ON THE PREVALENCE OF DRY EYES IN A TERTIARY CARE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Prashant V. Solanke

    2017-06-01

    Full Text Available BACKGROUND Dry eye syndrome is a common eye disease. Dry Eye Syndrome (DES, also known as Keratoconjunctivitis Sicca (KCS, is the condition of having dry eyes. Other associated symptoms include irritation, redness, discharge and easily fatigued eyes. Blurred vision may also occur. The symptoms can range from mild and occasional to severe and continuous. Scarring of the cornea may occur in some cases without treatment. Dry eye occurs when either the eye does not produce enough tears or when the tears evaporate too quickly. Tobacco smoke exposure or infection may also lead to the condition. Diagnosis is mostly based on the symptoms, though a number of other tests may be used. Prevalence of dry eyes are commoner in females than males. There is a positive relationship between glaucoma and ocular dryness as well as diabetic retinopathy and ocular dryness. Dry eye is a multifactorial disease of the tears and ocular surface. Ocular symptoms such as pain, irritation and poor vision can result from dry eye. The aim of the study is to study the prevalence, symptomatology and distribution of dry eyes. MATERIALS AND METHODS A cross-sectional study was conducted during July 2016 to March 2017. Study place was Outpatient Department of Ophthalmology at Sree Mookambika Institute of Medical Sciences, Kulasekharam. Sample size was calculated by 4PQ/d², which was 132. Systemic random sampling was used for the study. RESULTS Prevalence of dry eyes - 17.8%. Dry eyes in males - 16.8% and in females - 24.6%. Dry eyes in age 40 yrs. - 21.8%. Prevalence of dry eyes in contact lens wearers - 36.5%. Prevalence of dry eyes in glaucoma cases - 38.2%. Prevalence of dry eyes in farmers - 27.3%, in smokers - 36.7%. Dry eyes in emmetropes - 12.8% in myopes - 17.2% in hypermetropes - 28.6%. CONCLUSION Dry eyes prevalence obtained was 17.8%. Dry eyes were seen more in females. As age increases, prevalence of dry eyes increases. Ocular surface dryness was observed more in contact

  11. DFID-IDRC Program in Support of the African Institute for ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    A large number of these graduates enter advanced master's and doctoral programs in fields such as computer science, environmental science, and nuclear physics. This project will provide funding for AIMS-NEI to offer enhanced training in applied mathematics to top African students, allowing them to pursue high quality ...

  12. Herpetic Eye Disease in a Public Eye Hospital in Nigeria | Nwosu ...

    African Journals Online (AJOL)

    Objective: To determine the aetiology, pattern and complications of herpetic eye disease seen at the Guinness Eye Centre, Onitsha, Nigeria. Materials and Methods: The case files of all patients with herpetic eye disease who presented at the centre between January 1998 and December 2003 were reviewed. Information on ...

  13. Contact Lens-Related Eye Infections

    Science.gov (United States)

    ... Español Eye Health / Eye Health A-Z Contact Lens-Related Eye Infections Sections Contact Lens-Related Eye ... Six Steps to Avoid Contact Lens Infections Contact Lens-Related Eye Infections Leer en Español: Infecciones relacionadas ...

  14. Jakartans, Institutionally Volatile

    Directory of Open Access Journals (Sweden)

    Masaaki OKAMOTO

    2014-01-01

    Full Text Available Jakarta recently has gained even more central political attention in Indonesia since Joko Widodo (Jokowi and Basuki Purnama (Ahok became, respectively, the province’s governor and vice-governor in 2012. They started a series of eye-catching and populist programmes, drawing popular support from not only the people of Jakarta, but also among Indonesians in general. Jokowi is now even the most popular candidate for the presidential election in 2014. Their rise is phenomenal in this sense, but it is understandable if we look at Jakartan voters’ behaviour and the institutional arrangement that leads to it. Jakarta, as the national capital, has a unique arrangement in that the province has no autonomous regency or city. This paper argues that this arrangement causes Jakartans to be more politically volatile and describes how this institutional arrangement was created by analysing the minutes of the meeting to discuss the laws concerning Jakarta Province.

  15. Vision-Related Quality of Life in Patients with Inactive HLA-B27-Associated-Spectrum Anterior Uveitis.

    Directory of Open Access Journals (Sweden)

    Lisette Hoeksema

    Full Text Available We investigated the vision-related quality of life (VR-QOL in patients with HLA-B27 associated anterior uveitis (AU. The study was conducted in 2012 at the ophthalmology department of the University Medical Center of Groningen. We included AU patients who were HLA-B27 positive and/or were diagnosed by a rheumatologist with an HLA-B27 associated systemic disease. Sixty-one of 123 (50% adult patients participated. All patients filled-out the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25, Beck Depression Inventory (BDI-II, social support lists and an additional questionnaire for gathering general information. Medical records were reviewed for clinical characteristics. Analyses were conducted on various patient and ocular characteristics. We compared our NEI VFQ-25 scores with those previously found in the literature. Our main outcome measures were VR-QOL scores and their associations with various general patient and ocular characteristics. We found that the NEI VFQ-25 mean overall composite score was 88.9±8.8, which is relatively high, but lower than that found in a normal working population. The mean general health score was 47.4±20.8, which is lower than in patients with other ocular diseases. Patients with a systemic disease scored significantly lower on general health and VR-QOL, compared to patients without a systemic disease. Patients with a depression (6/59 (10% frequently had ankylosing spondylitis (5/6 patients and they scored significantly worse on VR-QOL. We concluded that patients with HLA-B27 associated AU have a relatively high VR-QOL. However, the presence of a systemic disease is associated with lower VR-QOL and general health scores. In addition, depression is associated with a lower VR-QOL.

  16. Vision-Related Quality of Life in Patients with Inactive HLA-B27–Associated-Spectrum Anterior Uveitis

    Science.gov (United States)

    Hoeksema, Lisette; Los, Leonoor I.

    2016-01-01

    We investigated the vision-related quality of life (VR-QOL) in patients with HLA-B27 associated anterior uveitis (AU). The study was conducted in 2012 at the ophthalmology department of the University Medical Center of Groningen. We included AU patients who were HLA-B27 positive and/or were diagnosed by a rheumatologist with an HLA-B27 associated systemic disease. Sixty-one of 123 (50%) adult patients participated. All patients filled-out the National Eye Institute Visual Functioning Questionnaire-25 (NEI VFQ-25), Beck Depression Inventory (BDI-II), social support lists and an additional questionnaire for gathering general information. Medical records were reviewed for clinical characteristics. Analyses were conducted on various patient and ocular characteristics. We compared our NEI VFQ-25 scores with those previously found in the literature. Our main outcome measures were VR-QOL scores and their associations with various general patient and ocular characteristics. We found that the NEI VFQ-25 mean overall composite score was 88.9±8.8, which is relatively high, but lower than that found in a normal working population. The mean general health score was 47.4±20.8, which is lower than in patients with other ocular diseases. Patients with a systemic disease scored significantly lower on general health and VR-QOL, compared to patients without a systemic disease. Patients with a depression (6/59 (10%)) frequently had ankylosing spondylitis (5/6 patients) and they scored significantly worse on VR-QOL. We concluded that patients with HLA-B27 associated AU have a relatively high VR-QOL. However, the presence of a systemic disease is associated with lower VR-QOL and general health scores. In addition, depression is associated with a lower VR-QOL. PMID:26808922

  17. Degeneration of rapid eye movement sleep circuitry underlies rapid eye movement sleep behavior disorder.

    Science.gov (United States)

    McKenna, Dillon; Peever, John

    2017-05-01

    During healthy rapid eye movement sleep, skeletal muscles are actively forced into a state of motor paralysis. However, in rapid eye movement sleep behavior disorder-a relatively common neurological disorder-this natural process is lost. A lack of motor paralysis (atonia) in rapid eye movement sleep behavior disorder allows individuals to actively move, which at times can be excessive and violent. At first glance this may sound harmless, but it is not because rapid eye movement sleep behavior disorder patients frequently injure themselves or the person they sleep with. It is hypothesized that the degeneration or dysfunction of the brain stem circuits that control rapid eye movement sleep paralysis is an underlying cause of rapid eye movement sleep behavior disorder. The link between brain stem degeneration and rapid eye movement sleep behavior disorder stems from the fact that rapid eye movement sleep behavior disorder precedes, in the majority (∼80%) of cases, the development of synucleinopathies such as Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy, which are known to initially cause degeneration in the caudal brain stem structures where rapid eye movement sleep circuits are located. Furthermore, basic science and clinical evidence demonstrate that lesions within the rapid eye movement sleep circuits can induce rapid eye movement sleep-specific motor deficits that are virtually identical to those observed in rapid eye movement sleep behavior disorder. This review examines the evidence that rapid eye movement sleep behavior disorder is caused by synucleinopathic neurodegeneration of the core brain stem circuits that control healthy rapid eye movement sleep and concludes that rapid eye movement sleep behavior disorder is not a separate clinical entity from synucleinopathies but, rather, it is the earliest symptom of these disorders. © 2017 International Parkinson and Movement Disorder Society. © 2017 International Parkinson and

  18. Eye Cancer

    Science.gov (United States)

    Cancer of the eye is uncommon. It can affect the outer parts of the eye, such as the eyelid, which are made up ... and nerves. If the cancer starts inside the eyeball it's called intraocular cancer. The most common intraocular ...

  19. Choosing Wisely When It Comes to Eye Care: Antibiotics for Eye Injections

    Science.gov (United States)

    ... Antibiotics for eye injections; and Punctal plugs for dry eye . This is the fourth in a series of ... why patients and their ophthalmologists should discuss treating dry eye with punctal plugs only after other treatment options ...

  20. Spectacle-related eye injuries, spectacle-impact performance and eye protection.

    Science.gov (United States)

    Hoskin, Annette K; Philip, Swetha; Dain, Stephen J; Mackey, David A

    2015-05-01

    The aim was to review the prevalence of spectacle-related ocular trauma and the performance of currently available spectacle materials and to identify the risk factors associated with spectacle-related ocular trauma. A literature review was conducted using Medline, Embase and Google with the keywords 'eyeglasses' OR 'spectacles' AND 'ocular injury' / 'eye injury'/ 'eye trauma' / 'ocular trauma'. Articles published prior to 1975 were excluded from this review because of advances in spectacle lens technology and Food and Drug Administration legislative changes requiring impact resistance of all prescription spectacle lenses in the United States. Six hundred and ninety-five individual ocular traumas, for which spectacles contributed to or were the main cause of injury, were identified in the literature. Eye injuries occurred when spectacles were worn in sports, in which medium- to high-impact energies were exerted from balls, racquets or bats and/or as a result of a collision with another player. Frame, lens design and product material choice were found to be associated with ocular injury, with polycarbonate lenses cited as the material of choice in the literature. International, regional and national standards for spectacle lenses had a wide range of impact requirements for prescription spectacle lenses, sports eye protection and occupational eye protection. Spectacle-related injury represents a small but preventable cause of ocular injury. With the increasing numbers of spectacle wearers and calls to spend more time outdoors to reduce myopia, spectacle wearers need to be made aware of the potential risks associated with wearing spectacles during medium- to high-risk activities. At particular risk are those prone to falls, the functionally one-eyed, those who have corneal thinning or have had previous eye surgery or injury. With increased understanding of specific risk factors, performance guidelines can be developed for prescription spectacle eye

  1. Design, Sensing and Control of a Robotic Prosthetic Eye for Natural Eye Movement

    OpenAIRE

    J. J. Gu; M. Meng; A. Cook; P. X. Liu

    2006-01-01

    Loss of an eye is a tragedy for a person, who may suffer psychologically and physically. This paper is concerned with the design, sensing and control of a robotic prosthetic eye that moves horizontally in synchronization with the movement of the natural eye. Two generations of robotic prosthetic eye models have been developed. The first generation model uses an external infrared sensor array mounted on the frame of a pair of eyeglasses to detect the natural eye movement and to feed the contro...

  2. System and Method for Eye Tracking

    DEFF Research Database (Denmark)

    2017-01-01

    A method and system for monitoring the motion of one or both eyes, includes capturing a sequence of overlapping images of a subject's face including an eye and the corresponding non-eye region; identifying a plurality of keypoints in each image; mapping corresponding keypoints in two or more images...... of the sequence; assigning the keypoints to the eye and to the corresponding non-eye region; calculating individual velocities of the corresponding keypoints in the eye and the corresponding non-eye region to obtain a distribution of velocities; extracting at least one velocity measured for the eye and at least...... one velocity measured for the corresponding non-eye region; calculating the eye-in-head velocity for the eye based upon the measured velocity for the eye and the measured velocity for the corresponding non-eye region; and calculating the eye-in-head position based upon the eye- in-head velocity....

  3. Organization of eye bank

    International Nuclear Information System (INIS)

    Reddy, S.C.

    1999-01-01

    Comeal transplantation is the only method of combating the blindness due to corneal opacity caused by infections, malnutrition, trauma and hereditary diseases. Comeal blindness is more prevalent in the developing countries. The availability of the donor cornea, trained ophthalmic surgeons and microsurgery facilities are the key factors in restoring vision in-patients with comeal blindness. The eye bank organization is somewhat similar to that of blood bank. The eye bank should be located in a hospital or a medical centre in which a laboratory may be established for the evaluation and storage of donor tissue. The medical director (Ophthalmologist), technician, secretary and public relation officer are the persons who play an important role in the successful organization of eye bank. The function of the eye bank are procurement, assessment, processing, distribution of donor eyes/corneas, training of technicians/doctors, and conducting research related to storage of donor tissue and corneal transplantation. The necessary infrastructure required for the organization of an eye bank include separate accommodation area for the personnel and the laboratory, telephone, computer, refrigerator, laminar air flow hood. Slitlamp, specular microscope, storage media and equipment, instrument for enucleation of donor eyes, and a motor vehicle. The details of responsibilities of the staff of eye bank, source of donor eyes, suitability of donor material, procurement of the donor cornea, tissue assessment, storage and preservation, distribution of donor tissue, and limitation of eye bank will be discussed at the time of presentation

  4. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Ophthalmology/Strabismus Ocular Pathology/Oncology Oculoplastics/Orbit Refractive Management/Intervention Retina/Vitreous Uveitis Focus On ... Dry Eye Sections What Is Dry Eye? Dry Eye Symptoms Causes of ...

  5. Eye-based head gestures

    DEFF Research Database (Denmark)

    Mardanbegi, Diako; Witzner Hansen, Dan; Pederson, Thomas

    2012-01-01

    A novel method for video-based head gesture recognition using eye information by an eye tracker has been proposed. The method uses a combination of gaze and eye movement to infer head gestures. Compared to other gesture-based methods a major advantage of the method is that the user keeps the gaze...... mobile phone screens. The user study shows that the method detects a set of defined gestures reliably.......A novel method for video-based head gesture recognition using eye information by an eye tracker has been proposed. The method uses a combination of gaze and eye movement to infer head gestures. Compared to other gesture-based methods a major advantage of the method is that the user keeps the gaze...

  6. iDEAS: A web-based system for dry eye assessment.

    Science.gov (United States)

    Remeseiro, Beatriz; Barreira, Noelia; García-Resúa, Carlos; Lira, Madalena; Giráldez, María J; Yebra-Pimentel, Eva; Penedo, Manuel G

    2016-07-01

    Dry eye disease is a public health problem, whose multifactorial etiology challenges clinicians and researchers making necessary the collaboration between different experts and centers. The evaluation of the interference patterns observed in the tear film lipid layer is a common clinical test used for dry eye diagnosis. However, it is a time-consuming task with a high degree of intra- as well as inter-observer variability, which makes the use of a computer-based analysis system highly desirable. This work introduces iDEAS (Dry Eye Assessment System), a web-based application to support dry eye diagnosis. iDEAS provides a framework for eye care experts to collaboratively work using image-based services in a distributed environment. It is composed of three main components: the web client for user interaction, the web application server for request processing, and the service module for image analysis. Specifically, this manuscript presents two automatic services: tear film classification, which classifies an image into one interference pattern; and tear film map, which illustrates the distribution of the patterns over the entire tear film. iDEAS has been evaluated by specialists from different institutions to test its performance. Both services have been evaluated in terms of a set of performance metrics using the annotations of different experts. Note that the processing time of both services has been also measured for efficiency purposes. iDEAS is a web-based application which provides a fast, reliable environment for dry eye assessment. The system allows practitioners to share images, clinical information and automatic assessments between remote computers. Additionally, it save time for experts, diminish the inter-expert variability and can be used in both clinical and research settings. Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

  7. The Mozart effect in biofeedback visual rehabilitation: a case report

    Directory of Open Access Journals (Sweden)

    Salvatore S

    2011-09-01

    Full Text Available Serena Salvatore, Aloisa Librando, Mariacristina Esposito, Enzo M VingoloDepartment of Ophthalmology, University La Sapienza, Polo Pontino, Alfredo Fiorini Hospital, Terracina, ItalyPurpose: To evaluate the usefulness of acoustic biofeedback by means of Mozart’s Sonata for Two Pianos in D Major K. 448 to maintain and/or restore visual performance in a patient with macular pucker and glaucoma.Methods: A 74-year-old patient with open angle glaucoma in both eyes and macular pucker in the right eye (RE underwent visual rehabilitation with acoustic biofeedback by means of the MAIA™ Vision Training Module (Centervue, Padova, Italy 10 minutes each eye once a week for 5 weeks. The patient was asked to move his eyes according to a sound which changed into Mozart’s Sonata for Two Pianos when the patient locked the fixation target.Results: Best-corrected visual acuity improved in his right eye (RE and was stable in the left eye (LE. Fixation stability improved in both eyes, and retinal sensitivity decreased in the RE and improved in the LE. The characteristic of the macular pucker did not change during the training as demonstrated with optical coherence tomography. The patient was very satisfied with the training, as demonstrated by a 25-item questionnaire (National Eye Institute – Visual Functioning Questionnaire, NEI-VFQ-25. The patient’s reading speed and the character size which he was able to read improved in his RE.Conclusion: Music could enhance synaptic plasticity and affect neural learning and fixation training by means of MAIA vision training. Therefore it can improve visual performance in patients with macular pucker, postpone the surgical time, and assure a better quality of life for the patient.Keywords: glaucoma, macular cellophane, music, vision training

  8. In the eye of the beholder: eye contact increases resistance to persuasion.

    Science.gov (United States)

    Chen, Frances S; Minson, Julia A; Schöne, Maren; Heinrichs, Markus

    2013-11-01

    Popular belief holds that eye contact increases the success of persuasive communication, and prior research suggests that speakers who direct their gaze more toward their listeners are perceived as more persuasive. In contrast, we demonstrate that more eye contact between the listener and speaker during persuasive communication predicts less attitude change in the direction advocated. In Study 1, participants freely watched videos of speakers expressing various views on controversial sociopolitical issues. Greater direct gaze at the speaker's eyes was associated with less attitude change in the direction advocated by the speaker. In Study 2, we instructed participants to look at either the eyes or the mouths of speakers presenting arguments counter to participants' own attitudes. Intentionally maintaining direct eye contact led to less persuasion than did gazing at the mouth. These findings suggest that efforts at increasing eye contact may be counterproductive across a variety of persuasion contexts.

  9. Creation of nano eye-drops and effective drug delivery to the interior of the eye

    Science.gov (United States)

    Ikuta, Yoshikazu; Aoyagi, Shigenobu; Tanaka, Yuji; Sato, Kota; Inada, Satoshi; Koseki, Yoshitaka; Onodera, Tsunenobu; Oikawa, Hidetoshi; Kasai, Hitoshi

    2017-03-01

    Nano eye-drops are a new type of ophthalmic treatment with increased potency and reduced side effects. Compounds in conventional eye-drops barely penetrate into the eye because the cornea, located at the surface of eye, has a strong barrier function for preventing invasion of hydrophilic or large-sized materials from the outside. In this work, we describe the utility of nano eye-drops utilising brinzolamide, a commercially available glaucoma treatment drug, as a target compound. Fabrication of the nanoparticles of brinzolamide prodrug increases the eye penetration rate and results in high drug efficacy, compared with that of commercially available brinzolamide eye-drops formulated as micro-sized structures. In addition, the resulting nano eye-drops were not toxic to the corneal epithelium after repeated administration for 1 week. The nano eye-drops may have applications as a next-generation ophthalmic treatment.

  10. BullsEye

    DEFF Research Database (Denmark)

    Klokmose, Clemens Nylandsted; Kristensen, Janus Bager; Bagge, Rolf

    2014-01-01

    implemented primarily in shaders on the GPU. The techniques are realized in the BullsEye computer vision software. We demonstrate experimentally that BullsEye provides sub-pixel accuracy down to a tenth of a pixel, which is a significant improvement compared to the commonly used reacTIVision software....

  11. Registration of eye reflection and scene images using an aspherical eye model.

    Science.gov (United States)

    Nakazawa, Atsushi; Nitschke, Christian; Nishida, Toyoaki

    2016-11-01

    This paper introduces an image registration algorithm between an eye reflection and a scene image. Although there are currently a large number of image registration algorithms, this task remains difficult due to nonlinear distortions at the eye surface and large amounts of noise, such as iris texture, eyelids, eyelashes, and their shadows. To overcome this issue, we developed an image registration method combining an aspherical eye model that simulates nonlinear distortions considering eye geometry and a two-step iterative registration strategy that obtains dense correspondence of the feature points to achieve accurate image registrations for the entire image region. We obtained a database of eye reflection and scene images featuring four subjects in indoor and outdoor scenes and compared the registration performance with different asphericity conditions. Results showed that the proposed approach can perform accurate registration with an average accuracy of 1.05 deg by using the aspherical cornea model. This work is relevant for eye image analysis in general, enabling novel applications and scenarios.

  12. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Member Services Advocacy Foundation About Subspecialties & More Eye Health Home Annual Meeting Clinical Education Practice Management Member ... Center Redmond Ethics Center Global Ophthalmology Guide Eye Health Find an Ophthalmologist Academy Store Eye Health A- ...

  13. What Is Dry Eye?

    Medline Plus

    Full Text Available ... Dry Eye Symptoms Related Ask an Ophthalmologist Answers Can a six-month dissolvable punctal plug be removed ... my eyes dry after LASIK? Jun 19, 2016 Can I be tested whether I close my eyes ...

  14. Recognizing and Treating Eye Injuries

    Science.gov (United States)

    ... Eye Injuries First Aid for Eye Scratches Protective Eyewear Children’s Eye Injuries: Prevention and Care Eye Injuries ... Academy Jobs at the Academy Financial Relationships with Industry Medical Disclaimer Privacy Policy Terms of Service For ...

  15. Comparison of novel lipid-based eye drops with aqueous eye drops for dry eye: a multicenter, randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Simmons PA

    2015-04-01

    Full Text Available Peter A Simmons, Cindy Carlisle-Wilcox, Joseph G Vehige Ophthalmology Research and Development, Allergan, Inc., Irvine, CA, USA Background: Dry eye may be caused or exacerbated by deficient lipid secretion. Recently, lipid-containing artificial tears have been developed to alleviate this deficiency. Our study compared the efficacy, safety, and acceptability of lipid-containing eye drops with that of aqueous eye drops.Methods: A non-inferiority, randomized, parallel-group, investigator-masked multicenter trial was conducted. Subjects with signs and symptoms of dry eye were randomized to use one of two lipid-containing artificial tears, or one of two aqueous artificial tears. Subjects instilled assigned drops in each eye at least twice daily for 30 days. The primary efficacy analysis tested non-inferiority of a preservative-free lipid tear formulation (LT UD to a preservative-free aqueous tear formulation (AqT UD for change in Ocular Surface Disease Index (OSDI score from baseline at day 30. Secondary measures included OSDI at day 7, tear break-up time (TBUT, corneal and conjunctival staining, Schirmer’s test, acceptability and usage questionnaires, and safety assessments.Results: A total of 315 subjects were randomized and included in the analyses. Subjects reported instilling a median of three doses of study eye drops per day in all groups. At days 7 and 30, all groups showed statistically significant improvements from baseline in OSDI (P<0.001 and TBUT (P≤0.005. LT UD was non-inferior to AqT UD for mean change from baseline in OSDI score at day 30. No consistent or clinically relevant differences for the other efficacy variables were observed. Acceptability was generally similar across the groups and there was a low incidence of adverse events.Conclusion: In this heterogeneous population of dry eye subjects, there were no clinically significant differences in safety, effectiveness, and acceptability between lipid-containing artificial tears

  16. Plasma rich in growth factors eye drops to treat secondary ocular surface disorders in patients with glaucoma

    Directory of Open Access Journals (Sweden)

    Sánchez-Avila RM

    2018-05-01

    Full Text Available Ronald M Sánchez-Avila,1 Jesus Merayo-Lloves,1 Maria Laura Fernández,1,2 Luis Alberto Rodríguez-Gutiérrez,1 Pedro Pablo Rodríguez-Calvo,1 Andres Fernández-Vega Cueto,1 Francisco Muruzabal,3,4 Gorka Orive,3–6 Eduardo Anitua3,4 1University Institute Fernández-Vega, Ophthalmological Research Foundation, University of Oviedo, Oviedo, Spain; 2Quilmes Eye Center, Buenos Aires, Argentina; 3University Institute for Regenerative Medicine and Oral Implantology (UIRMI, University of the Basque Country, Eduardo Anitua Foundation, Vitoria, Spain; 4Biotechnology Institute (BTI, Vitoria, Spain; 5Laboratory of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, University of the Basque Country, Vitoria, Spain; 6Networking Biomedical Research Center on Bioengineering, Biomaterials and Nanomedicine, CIBER-BBN, Vitoria, Spain Purpose: To evaluate the efficacy and safety of plasma rich in growth factors (PRGF eye drops in patients with glaucoma with secondary ocular surface disorders (OSDs due to surgeries and topical hypotensive drugs use. Materials and methods: A retrospective case-series study design was used including six patients (eight eyes diagnosed with glaucoma who received surgical (nonpenetrating deep sclerectomy and/or trabeculectomy and medical treatments (hypotensive eye drops to control intraocular pressure (IOP and who developed secondary OSDs, unresponsive to conventional treatments. Patients were treated with PRGF eye drops (four times a day. Outcome measures were ocular surface disease index (OSDI, best-corrected visual acuity (BCVA, in logarithm of the minimum angle of resolution, visual analog scale (VAS, frequency and severity of symptoms, and IOP. The safety of the treatment was also evaluated. Results: Six patients (seven eyes with open-angle glaucoma and one eye with uveitic glaucoma treated with PRGF eye drops were evaluated. Mean age was 71 years (SD=7.2, range 58–79 years. Five were female and one was male. The mean

  17. Evaluation of the Tobii EyeX Eye tracking controller and Matlab toolkit for research.

    Science.gov (United States)

    Gibaldi, Agostino; Vanegas, Mauricio; Bex, Peter J; Maiello, Guido

    2017-06-01

    The Tobii Eyex Controller is a new low-cost binocular eye tracker marketed for integration in gaming and consumer applications. The manufacturers claim that the system was conceived for natural eye gaze interaction, does not require continuous recalibration, and allows moderate head movements. The Controller is provided with a SDK to foster the development of new eye tracking applications. We review the characteristics of the device for its possible use in scientific research. We develop and evaluate an open source Matlab Toolkit that can be employed to interface with the EyeX device for gaze recording in behavioral experiments. The Toolkit provides calibration procedures tailored to both binocular and monocular experiments, as well as procedures to evaluate other eye tracking devices. The observed performance of the EyeX (i.e. accuracy < 0.6°, precision < 0.25°, latency < 50 ms and sampling frequency ≈55 Hz), is sufficient for some classes of research application. The device can be successfully employed to measure fixation parameters, saccadic, smooth pursuit and vergence eye movements. However, the relatively low sampling rate and moderate precision limit the suitability of the EyeX for monitoring micro-saccadic eye movements or for real-time gaze-contingent stimulus control. For these applications, research grade, high-cost eye tracking technology may still be necessary. Therefore, despite its limitations with respect to high-end devices, the EyeX has the potential to further the dissemination of eye tracking technology to a broad audience, and could be a valuable asset in consumer and gaming applications as well as a subset of basic and clinical research settings.

  18. Immunology of the eye

    OpenAIRE

    Weronika Ratajczak; Beata Tokarz-Deptuła; Wiesław Deptuła

    2018-01-01

    The eye is an organ of sight characterized by unusual immunological properties, resulting from its anatomical structure and physiology, as well as the presence of specific elements that, through the mechanisms of innate and adaptive immunity, provide homeostasis of the eyeball. This article reviews the defensive elements of individual eye structures: conjunctiva, cornea, lacrimal gland, anterior chamber of the eye, uvea, retina and eye-associated lymphoid tissue (EALT), where we distinguish a...

  19. First International Conference between West and East—Leonardo and Lao-Tze. Western Science Meets Eastern Wisdom. Experiences of Scientists and Intellectuals for the Creation of a New Paradigm of Modern Science

    Directory of Open Access Journals (Sweden)

    Flavio Daniele

    2008-01-01

    Full Text Available The Conference was organized and supported by: Nei Dan School (European School of Internal Martial Arts, NIB (Laboratory of Molecular Biology and Stem Cell Bioengineering, National Institute of Biostructures and Biosystems, Institute of Cardiology, S.Orsola-Malpighi Hospital, Bologna, WACIMA (Worldwide Association Chinese Internal Martial Arts, Arti D’Oriente (Magazine of Eastern culture and traditions, Nuovo Orizzonte (Taiji Quan School in Florence, Samurai (Journal on Martial Arts, and Pinus (First National Institute for the Unification of Medical Strategies. Nei Dan School (www.taichineidan.com, neidan@libero.it was in charge of the organization. Future meetings of the Centro studi ‘Tao and Science’ will take place in spring 2007 in Firenze and in October 2007 in Bologna. For information: E-mail: neidan@libero.it; web site: www.taichineidan.com, www.taoandscience.com.

  20. Choosing Wisely When It Comes to Eye Care: Punctal Plugs for Dry Eye

    Science.gov (United States)

    ... of Our 5-Part Series: Punctal Plugs for Dry Eye Making healthy lifestyle choices can help you protect ... discuss each item in detail. Punctal Plugs for Dry Eye Dry eye is a condition that millions of ...

  1. Transcriptome Analysis of the Planarian Eye Identifies ovo as a Specific Regulator of Eye Regeneration

    Directory of Open Access Journals (Sweden)

    Sylvain W. Lapan

    2012-08-01

    Full Text Available Among the millions of invertebrate species with visual systems, the genetic basis of eye development and function is well understood only in Drosophila melanogaster. We describe an eye transcriptome for the planarian Schmidtea mediterranea. Planarian photoreceptors expressed orthologs of genes required for phototransduction and microvillus structure in Drosophila and vertebrates, and optic pigment cells expressed solute transporters and melanin synthesis enzymes similar to those active in the vertebrate retinal pigment epithelium. Orthologs of several planarian eye genes, such as bestrophin-1 and Usher syndrome genes, cause eye defects in mammals when perturbed and were not previously described to have roles in invertebrate eyes. Five previously undescribed planarian eye transcription factors were required for normal eye formation during head regeneration. In particular, a conserved, transcription-factor-encoding ovo gene was expressed from the earliest stages of eye regeneration and was required for regeneration of all cell types of the eye.

  2. Transcriptome analysis of the planarian eye identifies ovo as a specific regulator of eye regeneration.

    Science.gov (United States)

    Lapan, Sylvain W; Reddien, Peter W

    2012-08-30

    Among the millions of invertebrate species with visual systems, the genetic basis of eye development and function is well understood only in Drosophila melanogaster. We describe an eye transcriptome for the planarian Schmidtea mediterranea. Planarian photoreceptors expressed orthologs of genes required for phototransduction and microvillus structure in Drosophila and vertebrates, and optic pigment cells expressed solute transporters and melanin synthesis enzymes similar to those active in the vertebrate retinal pigment epithelium. Orthologs of several planarian eye genes, such as bestrophin-1 and Usher syndrome genes, cause eye defects in mammals when perturbed and were not previously described to have roles in invertebrate eyes. Five previously undescribed planarian eye transcription factors were required for normal eye formation during head regeneration. In particular, a conserved, transcription-factor-encoding ovo gene was expressed from the earliest stages of eye regeneration and was required for regeneration of all cell types of the eye. Copyright © 2012 The Authors. Published by Elsevier Inc. All rights reserved.

  3. A laser-based eye-tracking system.

    Science.gov (United States)

    Irie, Kenji; Wilson, Bruce A; Jones, Richard D; Bones, Philip J; Anderson, Tim J

    2002-11-01

    This paper reports on the development of a new eye-tracking system for noninvasive recording of eye movements. The eye tracker uses a flying-spot laser to selectively image landmarks on the eye and, subsequently, measure horizontal, vertical, and torsional eye movements. Considerable work was required to overcome the adverse effects of specular reflection of the flying-spot from the surface of the eye onto the sensing elements of the eye tracker. These effects have been largely overcome, and the eye-tracker has been used to document eye movement abnormalities, such as abnormal torsional pulsion of saccades, in the clinical setting.

  4. Setting up a child eye care centre: the Mercy Eye Hospital, Abak ...

    African Journals Online (AJOL)

    Aim: To document and share our experience in setting up a Child Eye Care Centre within a rural mission eye hospital and document subsequent development of services. Method: The location of the project was Mercy Eye Hospital (MEH) Abak, Akwa Ibom State in the South South zone of Nigeria). Consent to commence ...

  5. Trustworthy-looking face meets brown eyes.

    Directory of Open Access Journals (Sweden)

    Karel Kleisner

    Full Text Available We tested whether eye color influences perception of trustworthiness. Facial photographs of 40 female and 40 male students were rated for perceived trustworthiness. Eye color had a significant effect, the brown-eyed faces being perceived as more trustworthy than the blue-eyed ones. Geometric morphometrics, however, revealed significant correlations between eye color and face shape. Thus, face shape likewise had a significant effect on perceived trustworthiness but only for male faces, the effect for female faces not being significant. To determine whether perception of trustworthiness was being influenced primarily by eye color or by face shape, we recolored the eyes on the same male facial photos and repeated the test procedure. Eye color now had no effect on perceived trustworthiness. We concluded that although the brown-eyed faces were perceived as more trustworthy than the blue-eyed ones, it was not brown eye color per se that caused the stronger perception of trustworthiness but rather the facial features associated with brown eyes.

  6. Understanding Zora Neale Hurston's Their Eyes Were Watching God

    Directory of Open Access Journals (Sweden)

    Tatjana Vukelić

    2007-12-01

    Full Text Available The work of Zora Neale Hurston, in particular, the novel Their Eyes Were Watching God, has been the object of more than a decade of critical attention. But, in addition to the critical consideration of Hurston's writings, her work has received the level of institutional support necessary for Hurston to enter the American literary mainstream. The article addresses the issue of black women literary tradition and the search for freedom and identity in the white American social and cultural environment.

  7. Eye movement perimetry in glaucoma.

    Science.gov (United States)

    Trope, G E; Eizenman, M; Coyle, E

    1989-08-01

    Present-day computerized perimetry is often inaccurate and unreliable owing to the need to maintain central fixation over long periods while repressing the normal response to presentation of peripheral stimuli. We tested a new method of perimetry that does not require prolonged central fixation. During this test eye movements were encouraged on presentation of a peripheral target. Twenty-three eyes were studied with an Octopus perimeter, with a technician monitoring eye movements. The sensitivity was 100% and the specificity 23%. The low specificity was due to the technician's inability to accurately monitor small eye movements in the central 6 degrees field. If small eye movements are monitored accurately with an eye tracker, eye movement perimetry could become an alternative method to standard perimetry.

  8. Eye movements in Multiple Object Tracking systematically lagging behind the scene content

    Czech Academy of Sciences Publication Activity Database

    Lukavský, Jiří

    2013-01-01

    Roč. 42, Suppl (2013), s. 42-43 ISSN 0301-0066. [36th European Conference on Visual Perception . 25.08.2013.-29.08.2013, Brémy] R&D Projects: GA ČR GA13-28709S Institutional support: RVO:68081740 Keywords : eye movements * attention * multiple object tracking Subject RIV: AN - Psychology http://www. perception web.com/abstract.cgi?id=v130146

  9. African Institute for Mathematical Sciences | CRDI - Centre de ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    Le succès que connaît l'AIMS-NEI a motivé le Department for International Development du Royaume-Uni à engager dans l'initiative une somme équivalant à 29 millions CAD sur cinq ans en 2012. Cette somme, administrée par le CRDI, a servi à l'établissement de trois autres centres et à l'octroi de fonds regroupés aux ...

  10. Advocacy for eye care

    Directory of Open Access Journals (Sweden)

    Thulasiraj D Ravilla

    2012-01-01

    Full Text Available The effectiveness of eye care service delivery is often dependant on how the different stakeholders are aligned. These stakeholders range from the ministries of health who have the capacity to grant government subsidies for eye care, down to the primary healthcare workers who can be enrolled to screen for basic eye diseases. Advocacy is a tool that can help service providers draw the attention of key stakeholders to a particular area of concern. By enlisting the support, endorsement and participation of a wider circle of players, advocacy can help to improve the penetration and effectiveness of the services provided. There are several factors in the external environmental that influence the eye care services - such as the availability of trained manpower, supply of eye care consumables, government rules and regulations. There are several instances where successful advocacy has helped to create an enabling environment for eye care service delivery. Providing eye care services in developing countries requires the support - either for direct patient care or for support services such as producing trained manpower or for research and dissemination. Such support, in the form of financial or other resources, can be garnered through advocacy.

  11. Prevention of Eye Injuries

    OpenAIRE

    Pashby, Tom

    1981-01-01

    In Canada 30,000 people are registered as blind; in one third of these, blindness might have been avoided. Prevention is the key to reducing the number of eye injuries and blind eyes. The role of the family physician in early identification of treatable conditions and in the education of patients is discussed, but responsibility for prevention belongs to all physicians. The success of prevention is seen in the great reduction in eye injuries in industry and sports since eye protectors have be...

  12. About the Eye

    Medline Plus

    Full Text Available ... Disease Education Program Glaucoma Education Program Low Vision Education Program ... Eye Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ...

  13. Outcomes of Thermal Pulsation Treatment for Dry Eye Syndrome in Patients With Sjogren Disease.

    Science.gov (United States)

    Godin, Morgan R; Stinnett, Sandra S; Gupta, Preeya K

    2018-04-26

    To evaluate the clinical outcomes of thermal pulsation treatment in patients with meibomian gland dysfunction (MGD) and dry eye secondary to Sjogren disease. Twenty-four eyes from 13 patients with previously diagnosed Sjogren disease who presented to our institution with dry eye symptoms and had thermal pulsation treatment were prospectively followed up. Patients underwent comprehensive slit-lamp examination, including MGD grading, gland oil flow, corneal and conjunctival staining scores, and tear break-up time (TBUT). Tear osmolarity was tested before and after treatment. The average patient age was 62.4 years (range, 31-78 yrs); 12 were women and 1 a man. The average meibomian gland oil flow score showed an increase from pretreatment 0.71 to 1.75 at 1 year posttreatment (range 9-15 months) (P = 0.001). The average corneal staining score decreased from a pretreatment grade of 1.04 to a posttreatment grade of 0.36 (P dry eye disease in patients with Sjogren disease and should not be overlooked when considering treatment options. Thermal pulsation is a therapeutic option for patients with Sjogren disease who have MGD and dry eye symptoms. After a single treatment, patients exhibited increased oil flow and tear break-up time with an associated decrease in corneal and conjunctival staining.

  14. Penetrating eye injury in war.

    Science.gov (United States)

    Biehl, J W; Valdez, J; Hemady, R K; Steidl, S M; Bourke, D L

    1999-11-01

    The percentage of penetrating eye injuries in war has increased significantly in this century compared with the total number of combat injuries. With the increasing use of fragmentation weapons and possibly laser weapons on the battle-field in the future, the rate of eye injuries may exceed the 13% of the total military injuries found in Operations Desert Storm/Shield. During the Iran-Iraq War (1980-1988), eye injuries revealed that retained foreign bodies and posterior segment injuries have an improved prognosis in future military ophthalmic surgery as a result of modern diagnostic and treatment modalities. Compared with the increasing penetrating eye injuries on the battlefield, advances in ophthalmic surgery are insignificant. Eye armor, such as visors that flip up and down and protect the eyes from laser injury, needs to be developed. Similar eye protection is being developed in civilian sportswear. Penetrating eye injury in the civilian sector is becoming much closer to the military model and is now comparable for several reasons.

  15. Danish Rural Eye Study

    DEFF Research Database (Denmark)

    Høeg, Tracy Beth; Ellervik, Christina; Buch, Helena

    2016-01-01

    , Danish Rural Eye Study (DRES). All DRES participants received a comprehensive general health examination preceding their eye examination, including measurement of best-corrected visual acuity (BCVA) for each eye, bilateral 45° retinal fundus photographs and further ophthalmological examination where...... indicated. RESULTS: Overall, 3826 of 3843 participants (99.6%) had bilateral visual acuity measurements. The overall frequency of VI (BCVA eye) was 0.4% (95% confidence interval, CI, 0.2-0.7%; n = 15) among all DRES participants, 0.6% (95% CI 0.3-1.0%; n = 15) among participants...... >50 years and 3.7% (95% CI 2.1-6.5%; n = 11) in participants >80 years. The primary causes of VI in the better-seeing eye were age-related macular degeneration (AMD) in 46.7% (7/15) and cataract in 26.7% (4/15). A total of 43.3% (n = 115) of participants >80 years were pseudophakic in one or both eyes...

  16. Clinical observation of Qiming granule combined with Dextran and Hypromellose eye drops for dry eye

    Directory of Open Access Journals (Sweden)

    Jin-Lan Wan

    2013-09-01

    Full Text Available AIM: To observe the efficacy of Qiming granule combined with Dextran and Hypromellose eye drops in treatment of dry eye.METHODS: A randomized, parallel-control approach was adopted, 100 cases of dry eye patients were divided into treatment group and control group equally, observation on the treatment of 3 months. The treatment group was applied Dextran and Hypromellose eye drops combined with oral Qiming granule, simply Dextran and Hypromellose eye drops for control group. Before and after treatment, tear secretion volume, break-up time, corneal fluorescein staining and symptom were observed.RESULTS: After treatment, there was statistical significance for the break-up time, SⅠt and corneal fluorescein staining in both groups when compared with before treatment(PPCONCLUSION: The combined Dextran and Hypromellose eye drops and Qiming granule perform better than Dextran and Hypromellose eye drops only in treatment of dry eye.

  17. Preventing Eye Injuries

    Science.gov (United States)

    ... Your Eyes Sep 20, 2017 Eye Injuries from Laundry Packets On the Rise Jun 30, 2017 ... Medical Disclaimer Privacy Policy Terms of Service For Advertisers For Media Ophthalmology Job Center © American ...

  18. Simultaneous measurement of eye stiffness and contact area for living human eyes.

    Science.gov (United States)

    Kurita, Yuichi; Iida, Yoshichika; Kaneko, Makoto; Mishima, Hiromu K; Katakura, Seiki; Kiuchi, Yoshiaki

    2007-01-01

    Goldmann applanation tonometry is commonly used for measuring IOP (IntraOcular Pressure) to diagnose glaucoma. However, the measured IOP by the applanation tonometry is valid only under the assumption that all the subjects have the same structural eye stiffness. Abnormal eye stiffness makes abnormal corneal deformation and thus the current applanation tonometer misestimates the IOP. This study challenges to measure the eye stiffness in vivo with a non-invasive approach for detecting the abnormal deformation. The deformation of the cornea and the contact area between the probe and the cornea are simultaneously captured by cameras during the experiment. Experimental results show that some subjects have different relationship among the force, the displacement and the contact area even with same IOP. The proposed eye stiffness measurement can help detecting the abnormal deformation and the eyes with misestimated IOP.

  19. Ganglion cell loss in relation to visual disability in multiple sclerosis.

    Science.gov (United States)

    Walter, Scott D; Ishikawa, Hiroshi; Galetta, Kristin M; Sakai, Reiko E; Feller, Daniel J; Henderson, Sam B; Wilson, James A; Maguire, Maureen G; Galetta, Steven L; Frohman, Elliot; Calabresi, Peter A; Schuman, Joel S; Balcer, Laura J

    2012-06-01

    We used high-resolution spectral-domain optical coherence tomography (SD-OCT) with retinal segmentation to determine how ganglion cell loss relates to history of acute optic neuritis (ON), retinal nerve fiber layer (RNFL) thinning, visual function, and vision-related quality of life (QOL) in multiple sclerosis (MS). Cross-sectional study. A convenience sample of patients with MS (n = 122; 239 eyes) and disease-free controls (n = 31; 61 eyes). Among MS eyes, 87 had a history of ON before enrollment. The SD-OCT images were captured using Macular Cube (200×200 or 512×128) and ONH Cube 200×200 protocols. Retinal layer segmentation was performed using algorithms established for glaucoma studies. Thicknesses of the ganglion cell layer/inner plexiform layer (GCL+IPL), RNFL, outer plexiform/inner nuclear layers (OPL+INL), and outer nuclear/photoreceptor layers (ONL+PRL) were measured and compared in MS versus control eyes and MS ON versus non-ON eyes. The relation between changes in macular thickness and visual disability was also examined. The OCT measurements of GCL+IPL and RNFL thickness; high contrast visual acuity (VA); low-contrast letter acuity (LCLA) at 2.5% and 1.25% contrast; on the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and 10-Item Neuro-Ophthalmic Supplement composite score. Macular RNFL and GCL+IPL were significantly decreased in MS versus control eyes (Pvisual function and vision-specific QOL in MS, and may serve as a useful structural marker of disease. Our findings parallel those of magnetic resonance imaging studies that show gray matter disease is a marker of neurologic disability in MS. Proprietary or commercial disclosure may be found after the references. Copyright © 2012 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  20. Pink Eye: What To Do

    Centers for Disease Control (CDC) Podcasts

    In this podcast, CDC's Adam Cohen, MD, a pediatrician and parent, discusses conjunctivitis (pink eye), a common eye condition in children and adults. He reviews pink eye causes and treatment, suggestions on when to call or visit a doctor, and practical tips to prevent pink eye from spreading.

  1. In the Eye of the Beholder-  A Survey of Models for Eyes and Gaze

    DEFF Research Database (Denmark)

    Witzner Hansen, Dan; Ji, Qiang

    2010-01-01

    Despite active research and significant progress in the last 30 years, eye detection and tracking remains challenging due to the individuality of eyes, occlusion, variability in scale, location, and light conditions. Data on eye location and details of eye movements have numerous applications and...

  2. NASA's "Eyes" Focus on Education

    Science.gov (United States)

    Hussey, K.

    2016-12-01

    NASA's "Eyes on…" suite of products continues to grow in capability and popularity. The "Eyes on the Earth", "Eyes on the Solar System" and "Eyes on Exoplanets" real-time, 3D interactive visualization products have proven themselves as highly effective demonstration and communication tools for NASA's Earth and Space Science missions. This presentation will give a quick look at the latest updates to the "Eyes" suite plus what is being done to make them tools for STEM Education.

  3. Dry Eye Disease Incidence Associated with Chronic Graft-Host Disease: Nonconcurrent Cohort Study (An American Ophthalmological Society Thesis)

    Science.gov (United States)

    Mian, Shahzad I.; De la Parra-Colín, Paola; De Melo-Franco, Rafael; Johnson, Christopher; Barrientos-Gutierrez, Tonatiuh

    2015-01-01

    Purpose: To determine if chronic graft-versus-host disease (cGVHD) after allogeneic hematopoietic stem cell transplantation (HSCT) is associated with stable or progressive dry eye disease and to determine the true incidence in patients with no prior history of dry eye disease. Methods: A nonconcurrent cohort study at a single institution with 136 patients who had no previous history of dry eye disease before HSCT. Survival analysis was used to estimate dry eye disease incidence. The incidence rate was calculated using life tables as the number of observed dry eye disease cases divided by the person-time at risk accumulated by the cohort. Transition probabilities were calculated from time of transplant to time of diagnosis, and then to last recorded visit. Results: Incidence rate was 0.8 cases of dry eye disease per person-year, and half of the population at risk developed dry eye disease during the first 10 months post transplant. Time to develop dry eye disease was 2.5 months for mild dry eye disease, 9.6 months for moderate dry eye disease, and 13.2 months for severe dry eye disease. In terms of cumulative incidence, 73% of subjects developed dry eye disease (50% mild, 16% moderate, and 7% severe) at the time of diagnosis. Conclusions: Our findings suggest that dry eye disease associated with cGVHD is an extremely frequent event and shows a wide spectrum of severity, with a mild form presenting early and a moderate to severe form presenting later after HSCT. These findings need to be studied further to elucidate if these are two different pathophysiological entities or just different expressions of the same pathology. PMID:27507907

  4. Eye Pull, Eye Push: Moving Objects between Large Screens and Personal Devices with Gaze and Touch

    OpenAIRE

    Turner , Jayson; Alexander , Jason; Bulling , Andreas; Schmidt , Dominik; Gellersen , Hans

    2013-01-01

    Part 4: Gaze-Enabled Interaction Design; International audience; Previous work has validated the eyes and mobile input as a viable approach for pointing at, and selecting out of reach objects. This work presents Eye Pull, Eye Push, a novel interaction concept for content transfer between public and personal devices using gaze and touch. We present three techniques that enable this interaction: Eye Cut & Paste, Eye Drag & Drop, and Eye Summon & Cast. We outline and discuss several scenarios in...

  5. Post-destructive eye surgery, associated depression at Sekuru Kaguvi Hospital Eye Unit, Zimbabwe: Pilot Study

    Directory of Open Access Journals (Sweden)

    M. M. Kawome

    2013-12-01

    Full Text Available Destructive eye surgery is associated with more complications than just loss of visual functions of the eye and aesthetics. Currently there is very little published literature on post-destructive eye surgery associated depression. Zimbabwe has been experiencing a surge in the rate of destructive eye surgery done at the National Tertiary Eye Unit. This situation could be churning out lots of unrecognized depressed clients into the community who require assistance in one form or another. Objectives: To determine the prevalence of post-destructive eye surgery associated depression among patients attending Sekuru Kaguvi Hospital Eye Unit and assess if the current management protocol of patients undergoing destructive eye surgery at the Eye Unit addresses the problem adequately. Methods: A cross-sectional study of 28 randomly selected patients who had destructive eye surgeries at Sekuru Kaguvi Hospital was conducted over five months from 1st March 2012 to end of July 2012. A structured questionnaire containing 15 questions on the following items: gender, age, diagnosis, surgical procedure done, expectations before and after surgery, adequacy of counseling given and involvement of family was used to collect data. Nine questions to assess depression were adapted from the Patient Health Questionnaire (PHQ-9. Setting:  The study was conducted at SekuruKaguvi Hospital Eye Unit, Parirenyatwa Group of Hospitals in Harare. Results:  Twenty-eight patients who underwent destructive eye surgery during the study period were selected using systematic random sampling. The gender ratio was 1:1 and the mean age was 38.7 years with a range from 24 to 65 years. Fifty percent of the patients in the study had orbital exenteration while the rest had enucleation (14% and evisceration (36%. Twenty-eight percent of the study population had depression. Conclusion: Destructive eye surgery is frequently associated with depression and our current management protocol of

  6. About the Eye

    Medline Plus

    Full Text Available ... The Visual System Your Eyes’ Natural Defenses Eye Health and Safety First Aid ... Your eyes are made up of many different parts that work together to help you see. Check out the ...

  7. Effect of rb-bFGF eye drops and hydroxyl indican eye drops on tear film stability and dry eye symptoms after age-related cataract surgery

    Directory of Open Access Journals (Sweden)

    Jing Chen

    2017-10-01

    Full Text Available AIM: To compare and analyze the effect of recombinant bovine basic fibroblast growth factor(bFGFeye drops and hydroxyl indican eye drops on the tear film stability and dry eye symptoms after age-related cataract surgery. METHODS: A total of 115 patients(115 affected eyeswith dry eyes after age-related cataract surgery were divided into the bFGF group, the hydroxyl indican group and the blank control group by the random number table method. The blank control group was only given routine anti-inflammatory treatment, and on the basis, the bFGF group and the hydroxyl indican group were treated with bFGF eye drops and hydroxyl indican eye drops respectively. The clinical efficacy, adverse reactions, changes in scores of dry eye symptoms, Schirmer test(SⅠt, tear film break-up time(BUTand corneal fluorescein staining(CFSscores at different time points were compared among the three groups. RESULTS: The total markedly effective rates in the bFGF group(89.5%was higher than that in the hydroxyl indican group(70.3%or the blank control group(47.5%(PPPCONCLUSION: The tear film is unstable in early stage after age-related cataract surgery, and there are dry eye symptoms. The intervention with bFGF eye drops and hydroxyl indican eye drops can effectively restore the tear film stability and significantly relieve dry eye symptoms, and the effect of bFGF eye drops is more significant.

  8. New Cricetid Rodents from Strata near the Eocene-Oligocene Boundary in Erden Obo Section (Nei Mongol, China).

    Science.gov (United States)

    Li, Qian; Meng, Jin; Wang, Yuanqing

    2016-01-01

    New cricetids (Eucricetodon wangae sp. nov., Eucricetodon sp. and Pappocricetodon siziwangqiensis sp. nov.) are reported from the lower and middle parts of the "Upper Red" beds of the Erden Obo section in Nei Mongol, China. Eucricetodon wangae is more primitive than other known species of the genus from lower Oligocene of Asia and Europe in having a single anterocone on M1, a single connection between the protocone and the paracone, the anterior metalophule connection in M1-2 and weaker anteroconid and ectomesolophid in lower molars. Pappocricetodon siziwangqiensis is more advanced than other species of the genus in permanently missing P4 and having posterior protolophule connection. These fossils suggest that the age of the "Upper Red" of the Erden Obo section is younger than the age of the Upper Eocene Houldjin and Caijiachong formations, but older than those containing the Shandgolian faunas; the "Upper Red" is most closely correlative to the Ergilian beds in age, and probably close to the Eocene/Oligocene boundary. Given the age estimate, Eucricetodon wangae provides the new evidence to support that cricetid dispersal from Asia to Europe occurred prior to the Eocene-Oligocene boundary.

  9. Eye Disease and Development

    DEFF Research Database (Denmark)

    Andersen, Thomas Barnebeck; Dalgaard, Carl-Johan Lars; Selaya, Pablo

    This research advances the hypothesis that cross-country variation in the historical incidence of eye disease has influenced the current global distribution of per capita income. The theory is that pervasive eye disease diminished the incentive to accumulate skills, thereby delaying the fertility...... transition and the take-off to sustained economic growth. In order to estimate the influence from eye disease incidence empirically, we draw on an important fact from the field of epidemiology: Exposure to solar ultraviolet B radiation (UVB-R) is an underlying determinant of several forms of eye disease...

  10. Post-LASIK dry eye

    Science.gov (United States)

    Shtein, Roni M

    2011-01-01

    Laser-assisted in situ keratomileusis (LASIK) is a frequently performed corneal refractive surgery with excellent refractive outcomes. The most common complication of LASIK is dry eyes, with virtually all patients developing some degree of dryness in the immediate postoperative period. Identifying preoperative dry eyes, and conscientious attention and treatment in the perioperative time period, can lead to enhanced patient satisfaction and more accurate visual outcomes. Improved understanding of the development of dry eyes after LASIK will advance our understanding of the complex pathophysiology of dry eye disease. PMID:22174730

  11. Clinical observation of Qiming granule combined with Dextran and Hypromellose eye drops for dry eye

    OpenAIRE

    Jin-Lan Wan; Ming-Chang Zhang

    2013-01-01

    AIM: To observe the efficacy of Qiming granule combined with Dextran and Hypromellose eye drops in treatment of dry eye.METHODS: A randomized, parallel-control approach was adopted, 100 cases of dry eye patients were divided into treatment group and control group equally, observation on the treatment of 3 months. The treatment group was applied Dextran and Hypromellose eye drops combined with oral Qiming granule, simply Dextran and Hypromellose eye drops for control group. Before and after tr...

  12. Eye and orbital cavity

    International Nuclear Information System (INIS)

    Panfilova, G.V.; Koval', G.Yu.

    1984-01-01

    Radioanatomy of eyes and orbit is described. Diseases of the orbit (developmental anomalies, inflammatory diseases, lacrimal apparatus deseases, toxoplasmosis, tumors and cysts et al.), methods of foreign body localization in the eye are considered. Roentgenograms of the orbit and calculation table for foreign body localization in spherical eyes of dissimilar diameter are presented

  13. About the Eye

    Medline Plus

    Full Text Available ... National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, ...

  14. About the Eye

    Medline Plus

    Full Text Available ... Ask a Scientist Video Series Glossary The Visual System Your Eyes’ Natural Defenses Eye Health and Safety ... much as it does on your eyes. ... of Health | USA.gov NIH…Turning Discovery Into Health ®

  15. About the Eye

    Medline Plus

    Full Text Available ... Vision Education Program Hispanic/Latino Program Vision and Aging Program African American Program Training and Jobs Fellowships ... Defenses Eye Health and Safety First Aid Tips Healthy Vision Tips Protective Eyewear Sports and Your Eyes ...

  16. simEye: computer-based simulation of visual perception under various eye defects using Zernike polynomials

    OpenAIRE

    Fink, Wolfgang; Micol, Daniel

    2006-01-01

    We describe a computer eye model that allows for aspheric surfaces and a three-dimensional computer-based ray-tracing technique to simulate optical properties of the human eye and visual perception under various eye defects. Eye surfaces, such as the cornea, eye lens, and retina, are modeled or approximated by a set of Zernike polynomials that are fitted to input data for the respective surfaces. A ray-tracing procedure propagates light rays using Snell’s law of refraction from an input objec...

  17. Investigation of extended blinks and interblink intervals in subjects with and without dry eye

    Directory of Open Access Journals (Sweden)

    Rodriguez JD

    2013-02-01

    Full Text Available John D Rodriguez,1 George W Ousler III,1 Patrick R Johnston,1 Keith Lane,1 Mark B Abelson1,21Ora, Inc, Andover, MA, 2Schepens Eye Research Institute and Harvard Medical School, Boston, MA, USABackground: The purpose of this study was to investigate the occurrence and duration of extended blinks ≥ 70 msec and their associated interblink intervals in normal subjects and in subjects with mild to moderate dry eye.Methods: This single-center, prospective, double-blind study included 11 subjects with dry eye and eight subjects with normal eyes. Extended blinks were defined as lid closure in at least two successive video frames (≥ 70 msec. Digital video imaging of each subject's eyes was recorded while the subject viewed a 10-minute documentary. The subjects did not know that blink was the outcome being measured. Following capture, the videos were manually analyzed in a masked fashion for the occurrence of extended blinks. The length of the interblink interval (ie, time between blinks before and after these extended blinks (the interblink interval ratio was calculated, as well as differences in lid contact times.Results: The dry eye group had a median extended blink duration which was 2.53 times longer than that of the normal group. For subjects with dry eye, interblink intervals post-extended blink were significantly longer than interblink intervals pre-extended blink (P < 0.001. Interblink intervals did not lengthen significantly in normal subjects. In both groups, the duration of the extended blink was significantly (P = 0.001 and positively correlated with interblink interval ratio (post-extended to pre-extended blink interblink interval, such that for each doubling of extended blink duration, the interblink interval ratio increased by 10%. Blinks longer than one second in duration occurred almost exclusively in subjects with dry eye.Conclusion: This study reports three central findings: blink duration tended to be longer in subjects with dry

  18. About the Eye

    Medline Plus

    Full Text Available ... NIH), the National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of ...

  19. About the Eye

    Medline Plus

    Full Text Available ... Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the ...

  20. About the Eye

    Medline Plus

    Full Text Available ... Clinical Director Laboratories, Sections and Units Division of Epidemiology and Clinical Applications eyeGENE Research Directors Office Office ... Diabetic Eye Disease Education Program Glaucoma Education Program Low Vision Education Program Hispanic/Latino Program Vision and ...

  1. Pink Eye (Conjunctivitis)

    Science.gov (United States)

    ... or child care if you're not able to take time off — just stay consistent in practicing good hygiene. Preventing pink eye in newborns Newborns' eyes are susceptible to bacteria normally present in the mother's birth canal. ...

  2. The all seeing eye?

    NARCIS (Netherlands)

    Koenderink, Jan J.

    2014-01-01

    The All Seeing Eye? Did you know that you are probably a believer in the All Seeing Eye? The odds are that I’m right—why? Well, the bulk of mainstream vision literature blindly relies on the All Seeing Eye. It is written all over papers, albeit between the lines. Understandably so, for scientists

  3. Inflammation in dry eye.

    Science.gov (United States)

    Stern, Michael E; Pflugfelder, Stephen C

    2004-04-01

    Dry eye is a condition of altered tear composition that results from a diseased or dysfunctional lacrimal functional unit. Evidence suggests that inflammation causes structural alterations and/or functional paralysis of the tear-secreting glands. Changes in tear composition resulting from lacrimal dysfunction, increased evaporation and/or poor clearance have pro-inflammatory effects on the ocular surface. This inflammation is responsible in part for the irritation symptoms, ocular surface epithelial disease, and altered corneal epithelial barrier function in dry eye. Anti-inflammatory therapies for dry eye target one or more of the inflammatory mediators/pathways that have been identified in dry eye.

  4. About the Eye

    Medline Plus

    Full Text Available ... NIH), the National Eye Institute’s mission is to “conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and ...

  5. 'An eye, for eyes - mission' - From dream to reality

    Directory of Open Access Journals (Sweden)

    Parikumar P

    2013-10-01

    Full Text Available Corneal transplantation has been in routine practice to treat corneal endothelial diseases like Bullous Keratopathy, in which either the whole cornea or the partial cornea (the endothelium alone is transplanted from the cadaver donor to the recipient with the endothelial disease [1]. In whole corneal or partial corneal transplant one cadaver donor's cornea can be used to treat one recipient cornea only, which leads to a huge global shortage of donor corneas [2]. At this juncture Yokoo et al isolated and expanded corneal endothelial precursors using the sphere forming assay in vitro [3] and demonstrated the in vivo transplantation of these corneal endothelial precursors in a rabbit model of bullous keratopathy [4]. Following this, we studied the transportation of cadaver donor derived corneal endothelial tissue (CET from human cadaver donors in a thermoreversible gelation polymer (TGP (4 based transportation cocktail without cool preservation and demonstrated the viability of human corneal endothelial precursor (HCEP cells isolated from these CETs even after 72 hours of transportation without cool preservation [5]. This was done to suit the conditions existing in developing nations like India where hospitals might be located far from eye banks and maintaining cold chain preservation is relatively difficult. Further, these HCEPs were expanded in vitro using a polymer based expansion protocol [5]. This was the first step in the realisation of the dream of 'Eye for eyes' in a manner suitable for Indian conditions. Corneal transplantation has been in routine practice to treat corneal endothelial diseases like Bullous Keratopathy, in which either the whole cornea or the partial cornea (the endothelium alone is transplanted from the cadaver donor to the recipient with the endothelial disease [1]. In whole corneal or partial corneal transplant one cadaver donor's cornea can be used to treat one recipient cornea only, which leads to a huge global

  6. In vitro eye corrosion study of agrochemicals on isolated chicken eye.

    Science.gov (United States)

    Buda, I; Budai, P; Szabó, R; Lehel, J

    2013-01-01

    Agrochemicals must undergo numberless toxicological tests before marketing. The eye irritation test is part of this test packet. Nowadays, OECD 405 can be used to classify the irritation potential of substances, the base of the OECD 405 guideline is the Draize test, which is one of the most criticized in vivo methods because of the injuries of the test animals and subjective nature of the test in recording the results. Therefore, several in vitro tests have been developed to replace totally or partly the in vivo eye irritation testing. The isolated chicken eye test method (OECD 438), which was used, is one of these alternative methods. Five different agrochemicals were examined in the following way: All test compounds were applied in a single dose onto the cornea of isolated chicken eyes in order to potentially classify the test compounds as ocular corrosive and/or severe irritant. The damages caused by the test substances were assessed by the determination of corneal swelling, opacity, fluorescein retention and morphological effects. These parameters were evaluated pre-treatment and starting at approximately 30, 75, 120, 180, and 240 minutes after the post-treatment rinse. The endpoints evaluated were corneal opacity, swelling, fluorescein retention and morphological effects. All of the endpoints, with the exception of fluorescein retention (which was determined only at pre-treatment and 30 minutes after test substance exposure) were determined at each of the above time points. Positive and negative controls were used and they showed the expected results in each study. In these in vitro eye corrosives and severe irritants studies, using the Isolated Chicken Eye model with five different products, no ocular corrosion or severe irritation potential were observed. These results correspond to the available information about the tested agrochemicals, so these studies with isolated chicken eye are considered to be successful.

  7. The eye amputated - consequences of eye amputation with emphasis on clinical aspects, phantom eye syndrome and quality of life.

    Science.gov (United States)

    Rasmussen, Marie Louise Roed

    2010-12-01

    In this thesis the term eye amputation (EA) covers the removing of an eye by: evisceration, enucleation and exenteration. Amputation of an eye is most frequently the end-stage in a complicated disease, or the primary treatment in trauma and neoplasm. In 2010 the literature is extensive due to knowledge about types of surgery, implants and surgical technique. However, not much is known about the time past surgery. To identify the number of EA, the causative diagnosis and the indication for surgical removal of the eye, the chosen surgical technique and to evaluate a possible change in surgical technique in Denmark from 1996 until 2003 (paper I); To describe the phantom eye syndrome and its prevalence of visual hallucinations, phantom pain and phantom sensations (paper II); To characterise the quality of phantom eye pain, including its intensity and frequency among EA patients. We attempted to identify patients with increased risk of developing pain after EA and investigated if preoperative pain is a risk factor for a later development of phantom pain (paper III); In addition we wanted to investigate the health related quality of life, perceived stress, self rated health, job separation due to illness or disability and socio-economic position of the EA in comparison with the general Danish population (paper IV). Records on 431 EA patients, clinical ophthalmological examination and an interview study of 173 EA patients and a questionnaire answered by 120 EA patients. The most frequent indications for EA in Denmark were painful blind eye (37%) and neoplasm (34%). During the study period 1996-2003, the annual number of eye amputations was stable, but an increase in bulbar eviscerations was noticed. Orbital implants were used with an increasing tendency until 2003. The Phantom eye syndrome is frequent among EA patients. Visual hallucinations were described by 42% of the patients. The content were mainly elementary visual hallucinations, with white or colored light as a

  8. Effect of rb-bFGF eye drops and hydroxyl indican eye drops on tear film stability and dry eye symptoms after age-related cataract surgery

    Directory of Open Access Journals (Sweden)

    Yu Ling

    2018-01-01

    Full Text Available AIM: To investigate the effect of recombinant bovine basic fibroblast growth factor(rb-bFGFeye drops and hydroxyl indican eye drops on tear film stability and dry eye symptoms after age-related cataract surgery. METHODS: Totally 80 patients with 80 affected eyes undergoing age-related cataract surgery in our hospital from January 2015 to October 2016 were selected as study subjects, and they were randomly divided into control group and experimental group with 40 patients(40 affected eyesin each group. The two groups were treated with hydroxyl indican eye drops and rb-bFGF eye drops, respectively. The clinical curative effect, inflammation related factors \\〖interleukin 6(IL-6, tumor necrosis factor α(TNF-α\\〗, Schirmer test(SⅠt, break-up time(BUTof tear film, corneal sodium fluorescein staining(FLand scores of dry eye symptoms in the two groups were observed. RESULTS: The total treatment effective rate of experimental group after treatment was significantly higher than that of the control group(90.0% vs 72.5%; χ2=4.021, PP>0.05. After treatment, IL-6, TNF-α, SⅠt, FL score and scores of dry eye symptoms in two groups significantly decreased while BUT significantly increased(PPCONCLUSION: In the treatment of patients after age-related cataract after surgery, rb-bFGF eye drops has more advantages over hydroxyl indican eye drops in regulating the expression of inflammatory factors, improving the tear film stability and relieving dry eye symptoms.

  9. Managing Sjögren’s Syndrome and non-Sjögren Syndrome dry eye with anti-inflammatory therapy

    Directory of Open Access Journals (Sweden)

    Coursey TG

    2014-08-01

    Full Text Available Terry G Coursey, Cintia S de PaivaCullen Eye Institute, Baylor College of Medicine, Houston, TX, USAAbstract: Dry eye from Sjögren’s syndrome is a multifactorial disease that results in dysfunction of the lacrimal functional unit. Studies have shown changes in tear composition, including inflammatory cytokines, chemokines, and metalloproteinase. T-lymphocytes have been shown to increase in the conjunctiva and lacrimal glands in patient and animal models. This inflammation is in part responsible for the pathogenesis of the disease, which results in symptoms of eye irritation, ocular surface epithelial disease, and loss of corneal barrier function. There are a number of anti-inflammatory approaches for treating this disease. The current study reviews details of immune response and anti–inflammatory therapies used to control this disease.Keywords: keratoconjunctivitis sicca, SS, cyclosporin A, steroids, dry eye, Sjögren’s Syndrome

  10. Dry eye syndrome

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/000426.htm Dry eye syndrome To use the sharing features on this page, ... second-hand smoke exposure Cold or allergy medicines Dry eye can also be caused by: Heat or ... Symptoms may include: Blurred vision Burning, itching, ...

  11. The Tromsø Eye Study

    DEFF Research Database (Denmark)

    Bertelsen, Geir; Erke, Maja G; von Hanno, Therese

    2013-01-01

    Purpose:  To describe the study design and methodology of the Tromsø Eye Study (TES), and to describe visual acuity and refractive error in the study population. Methods:  The Tromsø Eye Study is a sub-study of the Tromsø Study, a population-based multipurpose longitudinal study in the municipality...... of Tromsø, Norway. The Tromsø Eye Study was a part of the sixth survey of the Tromsø Study, conducted from October 2007 through December 2008. The eye examination included information on self-reported eye diseases, assessment of visual acuity and refractive errors, retinal photography and optical coherence...

  12. Dry Eyes and Glaucoma: Double Trouble

    Science.gov (United States)

    ... Involved News About Us Donate In This Section Dry Eyes and Glaucoma: Double Trouble email Send this article ... eye disease bothers the patient more. What Causes Dry Eye Syndrome? Dry eye can be caused by many ...

  13. Eye-movements and ongoing task processing.

    Science.gov (United States)

    Burke, David T; Meleger, Alec; Schneider, Jeffrey C; Snyder, Jim; Dorvlo, Atsu S S; Al-Adawi, Samir

    2003-06-01

    This study tests the relation between eye-movements and thought processing. Subjects were given specific modality tasks (visual, gustatory, kinesthetic) and assessed on whether they responded with distinct eye-movements. Some subjects' eye-movements reflected ongoing thought processing. Instead of a universal pattern, as suggested by the neurolinguistic programming hypothesis, this study yielded subject-specific idiosyncratic eye-movements across all modalities. Included is a discussion of the neurolinguistic programming hypothesis regarding eye-movements and its implications for the eye-movement desensitization and reprocessing theory.

  14. Pink Eye: What To Do

    Centers for Disease Control (CDC) Podcasts

    2010-10-12

    In this podcast, CDC's Adam Cohen, MD, a pediatrician and parent, discusses conjunctivitis (pink eye), a common eye condition in children and adults. He reviews pink eye causes and treatment, suggestions on when to call or visit a doctor, and practical tips to prevent pink eye from spreading.  Created: 10/12/2010 by National Center for Immunization and Respiratory Diseases (NCIRD).   Date Released: 10/13/2010.

  15. Neuropathic pain and dry eye.

    Science.gov (United States)

    Galor, Anat; Moein, Hamid-Reza; Lee, Charity; Rodriguez, Adriana; Felix, Elizabeth R; Sarantopoulos, Konstantinos D; Levitt, Roy C

    2018-01-01

    Dry eye is a common, multifactorial disease currently diagnosed by a combination of symptoms and signs. Its epidemiology and clinical presentation have many similarities with neuropathic pain outside the eye. This review highlights the similarities between dry eye and neuropathic pain, focusing on clinical features, somatosensory function, and underlying pathophysiology. Implications of these similarities on the diagnosis and treatment of dry eye are discussed. Published by Elsevier Inc.

  16. The top 100 papers in dry eye - A bibliometric analysis.

    Science.gov (United States)

    Schargus, Marc; Kromer, Robert; Druchkiv, Vasily; Frings, Andreas

    2018-01-01

    Citation analysis represents one of the best currently available methods for quantifying the impact of articles. Bibliometric studies list the ''best sellers'' in a single field of interest. The purpose of the present study was to identify and analyze the most frequently cited papers in dry eye research that may be of high interest for researchers and clinicians. We reviewed the database of the Institute for Scientific Information to identify articles published from 1900 to September 2016. All dry eye articles published in 59 ophthalmology journals were identified. The top 100 articles were selected for further analysis of authorship, source journal, number of citations, citation rate, geographic origin, article type, and level of evidence. The 100 most-cited articles were published between 1983 and 2011, with most of them in the 2000s. The number of citations per article ranged from 96 to 610, and was greatest for articles published in the 2000s. Each of these articles was published in one of 15 journals. Most articles represented Level-III evidence, followed by Levels II and I. The present study focusing on dry eye research revealed that 55% of the most-cited articles came from the U.S. and 18% from Japan. Diagnostics and therapy were the areas of focus of most of the clinical articles; 13% of the most cited papers were review articles. This analysis provides researchers and clinicians with a detailed overview on the most cited dry eye papers over the past decades. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. The Eyes Are the Windows to the Mind: Direct Eye Gaze Triggers the Ascription of Others' Minds.

    Science.gov (United States)

    Khalid, Saara; Deska, Jason C; Hugenberg, Kurt

    2016-12-01

    Eye gaze is a potent source of social information with direct eye gaze signaling the desire to approach and averted eye gaze signaling avoidance. In the current work, we proposed that eye gaze signals whether or not to impute minds into others. Across four studies, we manipulated targets' eye gaze (i.e., direct vs. averted eye gaze) and measured explicit mind ascriptions (Study 1a, Study 1b, and Study 2) and beliefs about the likelihood of targets having mind (Study 3). In all four studies, we find novel evidence that the ascription of sophisticated humanlike minds to others is signaled by the display of direct eye gaze relative to averted eye gaze. Moreover, we provide evidence suggesting that this differential mentalization is due, at least in part, to beliefs that direct gaze targets are more likely to instigate social interaction. In short, eye contact triggers mind perception. © 2016 by the Society for Personality and Social Psychology, Inc.

  18. About the Eye

    Medline Plus

    Full Text Available ... luh) is the small, sensitive area of the retina needed for central vision. It contains the fovea. Lens is the clear part of the eye behind the iris that helps to focus light on the retina. It allows the eye to focus on both ...

  19. LASIK Eye Surgery

    Science.gov (United States)

    ... at the front of your eye — to improve vision. Normally, images are clearly focused on the retina in the back of your eye because the ... sharply, light rays focus in front of the retina and blur distant vision. You can see objects that are close fairly ...

  20. SyntEyes KTC: higher order statistical eye model for developing keratoconus.

    Science.gov (United States)

    Rozema, Jos J; Rodriguez, Pablo; Ruiz Hidalgo, Irene; Navarro, Rafael; Tassignon, Marie-José; Koppen, Carina

    2017-05-01

    To present and validate a stochastic eye model for developing keratoconus to e.g. improve optical corrective strategies. This could be particularly useful for researchers that do not have access to original keratoconic data. The Scheimpflug tomography, ocular biometry and wavefront of 145 keratoconic right eyes were collected. These data were processed using principal component analysis for parameter reduction, followed by a multivariate Gaussian fit that produces a stochastic model for keratoconus (SyntEyes KTC). The output of this model is filtered to remove the occasional incorrect topography patterns by either an automatic or manual procedure. Finally, the output of this keratoconus model is matched to that of the original model for normal eyes using the non-corneal biometry to obtain a description of keratoconus development. The synthetic data generated by the model were found to be significantly equal to the original data (non-parametric Mann-Whitney equivalence test; 145/154 passed). The variability of the synthetic data, however, was often significantly less than that of the original data, especially for the higher order Zernike terms of corneal elevation (non-parametric Levene test; p eyes with incorrect topographies. Interpolation between matched pairs of normal and keratoconic SyntEyes appears to provide an adequate model for keratoconus progression. The synthetic data provided by the proposed keratoconus model closely resembles actual clinical data and may be used for a range of research applications when (sufficient) real data is not available. © 2017 The Authors Ophthalmic & Physiological Optics © 2017 The College of Optometrists.