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Sample records for eye fixation patterns

  1. Start Position Strongly Influences Fixation Patterns during Face Processing: Difficulties with Eye Movements as a Measure of Information Use

    Science.gov (United States)

    Arizpe, Joseph; Kravitz, Dwight J.; Yovel, Galit; Baker, Chris I.

    2012-01-01

    Fixation patterns are thought to reflect cognitive processing and, thus, index the most informative stimulus features for task performance. During face recognition, initial fixations to the center of the nose have been taken to indicate this location is optimal for information extraction. However, the use of fixations as a marker for information use rests on the assumption that fixation patterns are predominantly determined by stimulus and task, despite the fact that fixations are also influenced by visuo-motor factors. Here, we tested the effect of starting position on fixation patterns during a face recognition task with upright and inverted faces. While we observed differences in fixations between upright and inverted faces, likely reflecting differences in cognitive processing, there was also a strong effect of start position. Over the first five saccades, fixation patterns across start positions were only coarsely similar, with most fixations around the eyes. Importantly, however, the precise fixation pattern was highly dependent on start position with a strong tendency toward facial features furthest from the start position. For example, the often-reported tendency toward the left over right eye was reversed for the left starting position. Further, delayed initial saccades for central versus peripheral start positions suggest greater information processing prior to the initial saccade, highlighting the experimental bias introduced by the commonly used center start position. Finally, the precise effect of face inversion on fixation patterns was also dependent on start position. These results demonstrate the importance of a non-stimulus, non-task factor in determining fixation patterns. The patterns observed likely reflect a complex combination of visuo-motor effects and simple sampling strategies as well as cognitive factors. These different factors are very difficult to tease apart and therefore great caution must be applied when interpreting absolute

  2. Maxwellian Eye Fixation during Natural Scene Perception

    Directory of Open Access Journals (Sweden)

    Jean Duchesne

    2012-01-01

    Full Text Available When we explore a visual scene, our eyes make saccades to jump rapidly from one area to another and fixate regions of interest to extract useful information. While the role of fixation eye movements in vision has been widely studied, their random nature has been a hitherto neglected issue. Here we conducted two experiments to examine the Maxwellian nature of eye movements during fixation. In Experiment 1, eight participants were asked to perform free viewing of natural scenes displayed on a computer screen while their eye movements were recorded. For each participant, the probability density function (PDF of eye movement amplitude during fixation obeyed the law established by Maxwell for describing molecule velocity in gas. Only the mean amplitude of eye movements varied with expertise, which was lower in experts than novice participants. In Experiment 2, two participants underwent fixed time, free viewing of natural scenes and of their scrambled version while their eye movements were recorded. Again, the PDF of eye movement amplitude during fixation obeyed Maxwell’s law for each participant and for each scene condition (normal or scrambled. The results suggest that eye fixation during natural scene perception describes a random motion regardless of top-down or of bottom-up processes.

  3. Maxwellian Eye Fixation during Natural Scene Perception

    Science.gov (United States)

    Duchesne, Jean; Bouvier, Vincent; Guillemé, Julien; Coubard, Olivier A.

    2012-01-01

    When we explore a visual scene, our eyes make saccades to jump rapidly from one area to another and fixate regions of interest to extract useful information. While the role of fixation eye movements in vision has been widely studied, their random nature has been a hitherto neglected issue. Here we conducted two experiments to examine the Maxwellian nature of eye movements during fixation. In Experiment 1, eight participants were asked to perform free viewing of natural scenes displayed on a computer screen while their eye movements were recorded. For each participant, the probability density function (PDF) of eye movement amplitude during fixation obeyed the law established by Maxwell for describing molecule velocity in gas. Only the mean amplitude of eye movements varied with expertise, which was lower in experts than novice participants. In Experiment 2, two participants underwent fixed time, free viewing of natural scenes and of their scrambled version while their eye movements were recorded. Again, the PDF of eye movement amplitude during fixation obeyed Maxwell's law for each participant and for each scene condition (normal or scrambled). The results suggest that eye fixation during natural scene perception describes a random motion regardless of top-down or of bottom-up processes. PMID:23226987

  4. Predicting Eye Fixations on Complex Visual Stimuli Using Local Symmetry.

    Science.gov (United States)

    Kootstra, Gert; de Boer, Bart; Schomaker, Lambert R B

    2011-03-01

    Most bottom-up models that predict human eye fixations are based on contrast features. The saliency model of Itti, Koch and Niebur is an example of such contrast-saliency models. Although the model has been successfully compared to human eye fixations, we show that it lacks preciseness in the prediction of fixations on mirror-symmetrical forms. The contrast model gives high response at the borders, whereas human observers consistently look at the symmetrical center of these forms. We propose a saliency model that predicts eye fixations using local mirror symmetry. To test the model, we performed an eye-tracking experiment with participants viewing complex photographic images and compared the data with our symmetry model and the contrast model. The results show that our symmetry model predicts human eye fixations significantly better on a wide variety of images including many that are not selected for their symmetrical content. Moreover, our results show that especially early fixations are on highly symmetrical areas of the images. We conclude that symmetry is a strong predictor of human eye fixations and that it can be used as a predictor of the order of fixation.

  5. The Relationship Between Problem Size and Fixation Patterns During Addition, Subtraction, Multiplication, and Division

    Directory of Open Access Journals (Sweden)

    Evan T. Curtis

    2016-08-01

    Full Text Available Eye-tracking methods have only rarely been used to examine the online cognitive processing that occurs during mental arithmetic on simple arithmetic problems, that is, addition and multiplication problems with single-digit operands (e.g., operands 2 through 9; 2 + 3, 6 x 8 and the inverse subtraction and division problems (e.g., 5 – 3; 48 ÷ 6. Participants (N = 109 solved arithmetic problems from one of the four operations while their eye movements were recorded. We found three unique fixation patterns. During addition and multiplication, participants allocated half of their fixations to the operator and one-quarter to each operand, independent of problem size. The pattern was similar on small subtraction and division problems. However, on large subtraction problems, fixations were distributed approximately evenly across the three stimulus components. On large division problems, over half of the fixations occurred on the left operand, with the rest distributed between the operation sign and the right operand. We discuss the relations between these eye tracking patterns and other research on the differences in processing across arithmetic operations.

  6. Taking a(c)count of eye movements: Multiple mechanisms underlie fixations during enumeration.

    Science.gov (United States)

    Paul, Jacob M; Reeve, Robert A; Forte, Jason D

    2017-03-01

    We habitually move our eyes when we enumerate sets of objects. It remains unclear whether saccades are directed for numerosity processing as distinct from object-oriented visual processing (e.g., object saliency, scanning heuristics). Here we investigated the extent to which enumeration eye movements are contingent upon the location of objects in an array, and whether fixation patterns vary with enumeration demands. Twenty adults enumerated random dot arrays twice: first to report the set cardinality and second to judge the perceived number of subsets. We manipulated the spatial location of dots by presenting arrays at 0°, 90°, 180°, and 270° orientations. Participants required a similar time to enumerate the set or the perceived number of subsets in the same array. Fixation patterns were systematically shifted in the direction of array rotation, and distributed across similar locations when the same array was shown on multiple occasions. We modeled fixation patterns and dot saliency using a simple filtering model and show participants judged groups of dots in close proximity (2°-2.5° visual angle) as distinct subsets. Modeling results are consistent with the suggestion that enumeration involves visual grouping mechanisms based on object saliency, and specific enumeration demands affect spatial distribution of fixations. Our findings highlight the importance of set computation, rather than object processing per se, for models of numerosity processing.

  7. Predicting Eye Fixations on Complex Visual Stimuli Using Local Symmetry

    NARCIS (Netherlands)

    Kootstra, Geert; de Boer, Bart; Schomaker, Lambertus

    Most bottom-up models that predict human eye fixations are based on contrast features. The saliency model of Itti, Koch and Niebur is an example of such contrast-saliency models. Although the model has been successfully compared to human eye fixations, we show that it lacks preciseness in the

  8. Predicting eye fixations on complex visual stimuli using local symmetry

    NARCIS (Netherlands)

    Kootstra, G.; de Boer, B.; Schomaker, L.R.B.

    2011-01-01

    Most bottom-up models that predict human eye fixations are based on contrast features. The saliency model of Itti, Koch and Niebur is an example of such contrast-saliency models. Although the model has been successfully compared to human eye fixations, we show that it lacks preciseness in the

  9. The role of eye fixation in memory enhancement under stress - An eye tracking study.

    Science.gov (United States)

    Herten, Nadja; Otto, Tobias; Wolf, Oliver T

    2017-04-01

    In a stressful situation, attention is shifted to potentially relevant stimuli. Recent studies from our laboratory revealed that participants stressed perform superior in a recognition task involving objects of the stressful episode. In order to characterize the role of a stress induced alteration in visual exploration, the present study investigated whether participants experiencing a laboratory social stress situation differ in their fixation from participants of a control group. Further, we aimed at shedding light on the relation of fixation behaviour with obtained memory measures. We randomly assigned 32 male and 31 female participants to a control or a stress condition consisting of the Trier Social Stress Test (TSST), a public speaking paradigm causing social evaluative threat. In an established 'friendly' control condition (f-TSST) participants talk to a friendly committee. During both conditions, the committee members used ten office items (central objects) while another ten objects were present without being used (peripheral objects). Participants wore eye tracking glasses recording their fixations. On the next day, participants performed free recall and recognition tasks involving the objects present the day before. Stressed participants showed enhanced memory for central objects, accompanied by longer fixation times and larger fixation amounts on these objects. Contrasting this, fixation towards the committee faces showed the reversed pattern; here, control participants exhibited longer fixations. Fixation indices and memory measures were, however, not correlated with each other. Psychosocial stress is associated with altered fixation behaviour. Longer fixation on objects related to the stressful situation may reflect enhanced encoding, whereas diminished face fixation suggests gaze avoidance of aversive, socially threatening stimuli. Modified visual exploration should be considered in future stress research, in particular when focussing on memory for a

  10. Decision-making in information seeking on texts: an eye-fixation-related potentials investigation.

    Science.gov (United States)

    Frey, Aline; Ionescu, Gelu; Lemaire, Benoit; López-Orozco, Francisco; Baccino, Thierry; Guérin-Dugué, Anne

    2013-01-01

    Reading on a web page is known to be not linear and people need to make fast decisions about whether they have to stop or not reading. In such context, reading, and decision-making processes are intertwined and this experiment attempts to separate them through electrophysiological patterns provided by the Eye-Fixation-Related Potentials technique (EFRPs). We conducted an experiment in which EFRPs were recorded while participants read blocks of text that were semantically highly related, moderately related, and unrelated to a given goal. Participants had to decide as fast as possible whether the text was related or not to the semantic goal given at a prior stage. Decision making (stopping information search) may occur when the paragraph is highly related to the goal (positive decision) or when it is unrelated to the goal (negative decision). EFRPs were analyzed on and around typical eye fixations: either on words belonging to the goal (target), subjected to a high rate of positive decisions, or on low frequency unrelated words (incongruent), subjected to a high rate of negative decisions. In both cases, we found EFRPs specific patterns (amplitude peaking between 51 to 120 ms after fixation onset) spreading out on the next words following the goal word and the second fixation after an incongruent word, in parietal and occipital areas. We interpreted these results as delayed late components (P3b and N400), reflecting the decision to stop information searching. Indeed, we show a clear spill-over effect showing that the effect on word N spread out on word N + 1 and N + 2.

  11. Fixational eye movement: a negligible source of dynamic aberration.

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    Mecê, Pedro; Jarosz, Jessica; Conan, Jean-Marc; Petit, Cyril; Grieve, Kate; Paques, Michel; Meimon, Serge

    2018-02-01

    To evaluate the contribution of fixational eye movements to dynamic aberration, 50 healthy eyes were examined with an original custom-built Shack-Hartmann aberrometer, running at a temporal frequency of 236Hz, with 22 lenslets across a 5mm pupil, synchronized with a 236Hz pupil tracker. A comparison of the dynamic behavior of the first 21 Zernike modes (starting from defocus) with and without digital pupil stabilization, on a 3.4s sequence between blinks, showed that the contribution of fixational eye movements to dynamic aberration is negligible. Therefore we highlighted the fact that a pupil tracker coupled to an Adaptive Optics Ophthalmoscope is not essential to achieve diffraction-limited resolution.

  12. Covering one eye in fixation-disparity measurement causes slight movement of fellow eye

    NARCIS (Netherlands)

    Simonsz, H. J.; Bour, L. J.

    1991-01-01

    In the subjective measurement of fixation disparity (FD), the subject fuses contours presented in the peripheral macular areas of both eyes (fusion lock). The position of the eyes relative to each other is monitored by means of two haploscopically seen vertical lines presented in the central macular

  13. Decision-making in information seeking on texts: an eye-fixation-related potentials investigation

    Science.gov (United States)

    Frey, Aline; Ionescu, Gelu; Lemaire, Benoit; López-Orozco, Francisco; Baccino, Thierry; Guérin-Dugué, Anne

    2013-01-01

    Reading on a web page is known to be not linear and people need to make fast decisions about whether they have to stop or not reading. In such context, reading, and decision-making processes are intertwined and this experiment attempts to separate them through electrophysiological patterns provided by the Eye-Fixation-Related Potentials technique (EFRPs). We conducted an experiment in which EFRPs were recorded while participants read blocks of text that were semantically highly related, moderately related, and unrelated to a given goal. Participants had to decide as fast as possible whether the text was related or not to the semantic goal given at a prior stage. Decision making (stopping information search) may occur when the paragraph is highly related to the goal (positive decision) or when it is unrelated to the goal (negative decision). EFRPs were analyzed on and around typical eye fixations: either on words belonging to the goal (target), subjected to a high rate of positive decisions, or on low frequency unrelated words (incongruent), subjected to a high rate of negative decisions. In both cases, we found EFRPs specific patterns (amplitude peaking between 51 to 120 ms after fixation onset) spreading out on the next words following the goal word and the second fixation after an incongruent word, in parietal and occipital areas. We interpreted these results as delayed late components (P3b and N400), reflecting the decision to stop information searching. Indeed, we show a clear spill-over effect showing that the effect on word N spread out on word N + 1 and N + 2. PMID:23966913

  14. Extracting information of fixational eye movements through pupil tracking

    Science.gov (United States)

    Xiao, JiangWei; Qiu, Jian; Luo, Kaiqin; Peng, Li; Han, Peng

    2018-01-01

    Human eyes are never completely static even when they are fixing a stationary point. These irregular, small movements, which consist of micro-tremors, micro-saccades and drifts, can prevent the fading of the images that enter our eyes. The importance of researching the fixational eye movements has been experimentally demonstrated recently. However, the characteristics of fixational eye movements and their roles in visual process have not been explained clearly, because these signals can hardly be completely extracted by now. In this paper, we developed a new eye movement detection device with a high-speed camera. This device includes a beam splitter mirror, an infrared light source and a high-speed digital video camera with a frame rate of 200Hz. To avoid the influence of head shaking, we made the device wearable by fixing the camera on a safety helmet. Using this device, the experiments of pupil tracking were conducted. By localizing the pupil center and spectrum analysis, the envelope frequency spectrum of micro-saccades, micro-tremors and drifts are shown obviously. The experimental results show that the device is feasible and effective, so that the device can be applied in further characteristic analysis.

  15. Assessment of Attentional Workload while Driving by Eye-fixation-related Potentials

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    Takeda, Yuji; Yoshitsugu, Noritoshi; Itoh, Kazuya; Kanamori, Nobuhiro

    How do drivers cope with the attentional workload of in-vehicle information technology? In the present study, we propose a new psychophysiological measure for assessing drivers' attention: eye-fixation-related potential (EFRP). EFRP is a kind of event-related brain potential measurable at the eye-movement situation that reflects how closely observers examine visual information at the eye-fixated position. In the experiment, the effects of verbal working memory load and spatial working memory load during simulated driving were examined by measuring the number of saccadic eye-movements and EFRP as the indices of drivers' attention. The results showed that the spatial working memory load affected both the number of saccadic eye-movements and the amplitude of the P100 component of EFRP, whereas the verbal working memory load affected only the number of saccadic eye-movements. This implies that drivers can perform time-sharing processing between driving and the verbal working memory task, but the decline of accuracy of visual processing during driving is inescapable when the spatial working memory load is given. The present study suggests that EFRP can provide a new index of drivers' attention, other than saccadic eye-movements.

  16. Relationship between abstract thinking and eye gaze pattern in patients with schizophrenia

    Science.gov (United States)

    2014-01-01

    Background Effective integration of visual information is necessary to utilize abstract thinking, but patients with schizophrenia have slow eye movement and usually explore limited visual information. This study examines the relationship between abstract thinking ability and the pattern of eye gaze in patients with schizophrenia using a novel theme identification task. Methods Twenty patients with schizophrenia and 22 healthy controls completed the theme identification task, in which subjects selected which word, out of a set of provided words, best described the theme of a picture. Eye gaze while performing the task was recorded by the eye tracker. Results Patients exhibited a significantly lower correct rate for theme identification and lesser fixation and saccade counts than controls. The correct rate was significantly correlated with the fixation count in patients, but not in controls. Conclusions Patients with schizophrenia showed impaired abstract thinking and decreased quality of gaze, which were positively associated with each other. Theme identification and eye gaze appear to be useful as tools for the objective measurement of abstract thinking in patients with schizophrenia. PMID:24739356

  17. Distinct eye movement patterns enhance dynamic visual acuity.

    Science.gov (United States)

    Palidis, Dimitrios J; Wyder-Hodge, Pearson A; Fooken, Jolande; Spering, Miriam

    2017-01-01

    Dynamic visual acuity (DVA) is the ability to resolve fine spatial detail in dynamic objects during head fixation, or in static objects during head or body rotation. This ability is important for many activities such as ball sports, and a close relation has been shown between DVA and sports expertise. DVA tasks involve eye movements, yet, it is unclear which aspects of eye movements contribute to successful performance. Here we examined the relation between DVA and the kinematics of smooth pursuit and saccadic eye movements in a cohort of 23 varsity baseball players. In a computerized dynamic-object DVA test, observers reported the location of the gap in a small Landolt-C ring moving at various speeds while eye movements were recorded. Smooth pursuit kinematics-eye latency, acceleration, velocity gain, position error-and the direction and amplitude of saccadic eye movements were linked to perceptual performance. Results reveal that distinct eye movement patterns-minimizing eye position error, tracking smoothly, and inhibiting reverse saccades-were related to dynamic visual acuity. The close link between eye movement quality and DVA performance has important implications for the development of perceptual training programs to improve DVA.

  18. Brief report: eye-movement patterns during an embedded figures test in children with ASD.

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    Keehn, Brandon; Brenner, Laurie A; Ramos, Aurora I; Lincoln, Alan J; Marshall, Sandra P; Müller, Ralph-Axel

    2009-02-01

    The present study examined fixation frequency and duration during an Embedded Figures Test (EFT) in an effort to better understand the attentional and perceptual processes by which individuals with autism spectrum disorder (ASD) achieve accelerated EFT performance. In particular, we aimed to elucidate differences in the patterns of eye-movement in ASD and typically developing (TD) children, thus providing evidence relevant to the competing theories of weak central coherence (WCC) and enhanced perceptual functioning. Consistent with prior EFT studies, we found accelerated response time (RT) in children with ASD. No group differences were seen for fixation frequency, but the ASD group made significantly shorter fixations compared to the TD group. Eye-movement results indicate that RT advantage in ASD is related to both WCC and enhanced perceptual functioning.

  19. Insights into numerical cognition: considering eye-fixations in number processing and arithmetic.

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    Mock, J; Huber, S; Klein, E; Moeller, K

    2016-05-01

    Considering eye-fixation behavior is standard in reading research to investigate underlying cognitive processes. However, in numerical cognition research eye-tracking is used less often and less systematically. Nevertheless, we identified over 40 studies on this topic from the last 40 years with an increase of eye-tracking studies on numerical cognition during the last decade. Here, we review and discuss these empirical studies to evaluate the added value of eye-tracking for the investigation of number processing. Our literature review revealed that the way eye-fixation behavior is considered in numerical cognition research ranges from investigating basic perceptual aspects of processing non-symbolic and symbolic numbers, over assessing the common representational space of numbers and space, to evaluating the influence of characteristics of the base-10 place-value structure of Arabic numbers and executive control on number processing. Apart from basic results such as reading times of numbers increasing with their magnitude, studies revealed that number processing can influence domain-general processes such as attention shifting-but also the other way round. Domain-general processes such as cognitive control were found to affect number processing. In summary, eye-fixation behavior allows for new insights into both domain-specific and domain-general processes involved in number processing. Based thereon, a processing model of the temporal dynamics of numerical cognition is postulated, which distinguishes an early stage of stimulus-driven bottom-up processing from later more top-down controlled stages. Furthermore, perspectives for eye-tracking research in numerical cognition are discussed to emphasize the potential of this methodology for advancing our understanding of numerical cognition.

  20. Capture of fixation by rotational flow; a deterministic hypothesis regarding scaling and stochasticity in fixational eye movements

    Directory of Open Access Journals (Sweden)

    Nicholas Mansel Wilkinson

    2014-02-01

    Full Text Available Visual scan paths exhibit complex, stochastic dynamics. Even during visual fixation, the eye is in constant motion. Fixational drift and tremor are thought to reflect fluctuations in the persistent neural activity of neural integrators in the oculomotor brainstem, which integrate sequences of transient saccadic velocity signals into a short term memory of eye position. Despite intensive research and much progress, the precise mechanisms by which oculomotor posture is maintained remain elusive. Drift exhibits a stochastic statistical profile which has been modelled using random walk formalisms. Tremor is widely dismissed as noise. Here we focus on the dynamical profile of fixational tremor, and argue that tremor may be a signal which usefully reflects the workings of the oculomotor postural control. We identify signatures reminiscent of a certain flavour of transient neurodynamics; toric travelling waves which rotate around a central phase singularity. Spiral waves play an organisational role in dynamical systems at many scales throughout nature, though their potential functional role in brain activity remains a matter of educated speculation. Spiral waves have a repertoire of functionally interesting dynamical properties, including persistence, which suggest that they could in theory contribute to persistent neural activity in the oculomotor postural control system. Whilst speculative, the singularity hypothesis of oculomotor postural control implies testable predictions, and could provide the beginnings of an integrated dynamical framework for eye movements across scales.

  1. How Hearing Impairment Affects Sentence Comprehension: Using Eye Fixations to Investigate the Duration of Speech Processing

    DEFF Research Database (Denmark)

    Wendt, Dorothea; Kollmeier, Birger; Brand, Thomas

    2015-01-01

    ; this measure uses eye fixations recorded while the participant listens to a sentence. Eye fixations toward a target picture (which matches the aurally presented sentence) were measured in the presence of a competitor picture. Based on the recorded eye fixations, the single target detection amplitude, which...... reflects the tendency of the participant to fixate the target picture, was used as a metric to estimate the duration of sentence processing. The single target detection amplitude was calculated for sentence structures with different levels of linguistic complexity and for different listening conditions......: in quiet and in two different noise conditions. Participants with hearing impairment spent more time processing sentences, even at high levels of speech intelligibility. In addition, the relationship between the proposed online measure and listener-specific factors, such as hearing aid use and cognitive...

  2. 14CO2 fixation pattern of cyanobacteria

    International Nuclear Information System (INIS)

    Erdmann, N.; Schiewer, U.

    1985-01-01

    The 14 CO 2 fixation pattern of three cyanobacteria in the light and dark were studied. Two different chromatographic methods widely used for separating labelled photosynthetic intermediates were compared. After ethanolic extraction, a rather uniform fixation pattern reflecting mainly the β-carboxylation pathway is obtained for all 3 species. Of the intermediates, glucosylglycerol is specific and high citrulline and low malate contents are fairly specific to cyanobacteria. The composition of the 14 CO 2 fixation pattern is hardly affected by changes in temperature or light intensity, but it is severely affected by changes in the water potential of the medium. (author)

  3. A new fixation aid for the radiotherapy of eye tumors

    International Nuclear Information System (INIS)

    Buchgeister, Markus; Grisanti, Salvatore; Suesskind, Daniela; Bamberg, Michael; Paulsen, Frank

    2007-01-01

    A modified swim goggle holding a light spot as an optical guide for actively aligning the eye in a reproducible orientation has been constructed to perform radiotherapy of ocular tumors. This device is compatible with computed tomography (CT) and magnetic resonance imaging systems. Image fusion of these data sets yielded clinically acceptable results. The reproducibility of the eye's positioning is tested by repeated CT. The eye's alignment during radiotherapy is monitored by an infrared TV camera with individual markings of the eye's position on the TV-monitor screen. From 2003-2006, 50 patients were treated with this fixation aid by radiosurgery with good patient compliance

  4. Ad gist : Ad communication in a single eye fixation

    NARCIS (Netherlands)

    Pieters, R.; Wedel, M.

    2012-01-01

    Most ads in practice receive no more than a single eye fixation. This study investigates the limits of what ads can communicate under such adverse exposure conditions. We find that consumers already know at maximum levels of accuracy and with high degree of certainty whether something is an ad or is

  5. The analysis of the influence of fractal structure of stimuli on fractal dynamics in fixational eye movements and EEG signal

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    Namazi, Hamidreza; Kulish, Vladimir V.; Akrami, Amin

    2016-05-01

    One of the major challenges in vision research is to analyze the effect of visual stimuli on human vision. However, no relationship has been yet discovered between the structure of the visual stimulus, and the structure of fixational eye movements. This study reveals the plasticity of human fixational eye movements in relation to the ‘complex’ visual stimulus. We demonstrated that the fractal temporal structure of visual dynamics shifts towards the fractal dynamics of the visual stimulus (image). The results showed that images with higher complexity (higher fractality) cause fixational eye movements with lower fractality. Considering the brain, as the main part of nervous system that is engaged in eye movements, we analyzed the governed Electroencephalogram (EEG) signal during fixation. We have found out that there is a coupling between fractality of image, EEG and fixational eye movements. The capability observed in this research can be further investigated and applied for treatment of different vision disorders.

  6. Right Visual Field Advantage in Parafoveal Processing: Evidence from Eye-Fixation-Related Potentials

    Science.gov (United States)

    Simola, Jaana; Holmqvist, Kenneth; Lindgren, Magnus

    2009-01-01

    Readers acquire information outside the current eye fixation. Previous research indicates that having only the fixated word available slows reading, but when the next word is visible, reading is almost as fast as when the whole line is seen. Parafoveal-on-foveal effects are interpreted to reflect that the characteristics of a parafoveal word can…

  7. Evaluating camouflage design using eye movement data.

    Science.gov (United States)

    Lin, Chiuhsiang Joe; Chang, Chi-Chan; Lee, Yung-Hui

    2014-05-01

    This study investigates the characteristics of eye movements during a camouflaged target search task. Camouflaged targets were randomly presented on two natural landscapes. The performance of each camouflage design was assessed by target detection hit rate, detection time, number of fixations on display, first saccade amplitude to target, number of fixations on target, fixation duration on target, and subjective ratings of search task difficulty. The results showed that the camouflage patterns could significantly affect the eye-movement behavior, especially first saccade amplitude and fixation duration, and the findings could be used to increase the sensitivity of the camouflage assessment. We hypothesized that the assessment could be made with regard to the differences in detectability and discriminability of the camouflage patterns. These could explain less efficient search behavior in eye movements. Overall, data obtained from eye movements can be used to significantly enhance the interpretation of the effects of different camouflage design. Copyright © 2013 Elsevier Ltd and The Ergonomics Society. All rights reserved.

  8. Scene perception in posterior cortical atrophy: categorization, description and fixation patterns.

    Science.gov (United States)

    Shakespeare, Timothy J; Yong, Keir X X; Frost, Chris; Kim, Lois G; Warrington, Elizabeth K; Crutch, Sebastian J

    2013-01-01

    Partial or complete Balint's syndrome is a core feature of the clinico-radiological syndrome of posterior cortical atrophy (PCA), in which individuals experience a progressive deterioration of cortical vision. Although multi-object arrays are frequently used to detect simultanagnosia in the clinical assessment and diagnosis of PCA, to date there have been no group studies of scene perception in patients with the syndrome. The current study involved three linked experiments conducted in PCA patients and healthy controls. Experiment 1 evaluated the accuracy and latency of complex scene perception relative to individual faces and objects (color and grayscale) using a categorization paradigm. PCA patients were both less accurate (faces < scenes < objects) and slower (scenes < objects < faces) than controls on all categories, with performance strongly associated with their level of basic visual processing impairment; patients also showed a small advantage for color over grayscale stimuli. Experiment 2 involved free description of real world scenes. PCA patients generated fewer features and more misperceptions than controls, though perceptual errors were always consistent with the patient's global understanding of the scene (whether correct or not). Experiment 3 used eye tracking measures to compare patient and control eye movements over initial and subsequent fixations of scenes. Patients' fixation patterns were significantly different to those of young and age-matched controls, with comparable group differences for both initial and subsequent fixations. Overall, these findings describe the variability in everyday scene perception exhibited by individuals with PCA, and indicate the importance of exposure duration in the perception of complex scenes.

  9. Scene perception in Posterior Cortical Atrophy: categorisation, description and fixation patterns

    Directory of Open Access Journals (Sweden)

    Timothy J Shakespeare

    2013-10-01

    Full Text Available Partial or complete Balint’s syndrome is a core feature of the clinico-radiological syndrome of posterior cortical atrophy (PCA, in which individuals experience a progressive deterioration of cortical vision. Although multi-object arrays are frequently used to detect simultanagnosia in the clinical assessment and diagnosis of PCA, to date there have been no group studies of scene perception in patients with the syndrome. The current study involved three linked experiments conducted in PCA patients and healthy controls. Experiment 1 evaluated the accuracy and latency of complex scene perception relative to individual faces and objects (colour and greyscale using a categorisation paradigm. PCA patients were both less accurate (faceseye tracking measures to compare patient and control eye movements over initial and subsequent fixations of scenes. Patients’ fixation patterns were significantly different to those of young and age-matched controls, with comparable group differences for both initial and subsequent fixations. Overall, these findings describe the variability in everyday scene perception exhibited by individuals with PCA, and indicate the importance of exposure duration in the perception of complex scenes.

  10. Eye movements and serial memory for visual-spatial information: does time spent fixating contribute to recall?

    Science.gov (United States)

    Saint-Aubin, Jean; Tremblay, Sébastien; Jalbert, Annie

    2007-01-01

    This research investigated the nature of encoding and its contribution to serial recall for visual-spatial information. In order to do so, we examined the relationship between fixation duration and recall performance. Using the dot task--a series of seven dots spatially distributed on a monitor screen is presented sequentially for immediate recall--performance and eye-tracking data were recorded during the presentation of the to-be-remembered items. When participants were free to move their eyes at their will, both fixation durations and probability of correct recall decreased as a function of serial position. Furthermore, imposing constant durations of fixation across all serial positions had a beneficial impact (though relatively small) on item but not order recall. Great care was taken to isolate the effect of fixation duration from that of presentation duration. Although eye movement at encoding contributes to immediate memory, it is not decisive in shaping serial recall performance. Our results also provide further evidence that the distinction between item and order information, well-established in the verbal domain, extends to visual-spatial information.

  11. In vivo retinal imaging for fixational eye motion detection using a high-speed digital micromirror device (DMD)-based ophthalmoscope.

    Science.gov (United States)

    Vienola, Kari V; Damodaran, Mathi; Braaf, Boy; Vermeer, Koenraad A; de Boer, Johannes F

    2018-02-01

    Retinal motion detection with an accuracy of 0.77 arcmin corresponding to 3.7 µm on the retina is demonstrated with a novel digital micromirror device based ophthalmoscope. By generating a confocal image as a reference, eye motion could be measured from consecutively measured subsampled frames. The subsampled frames provide 7.7 millisecond snapshots of the retina without motion artifacts between the image points of the subsampled frame, distributed over the full field of view. An ophthalmoscope pattern projection speed of 130 Hz enabled a motion detection bandwidth of 65 Hz. A model eye with a scanning mirror was built to test the performance of the motion detection algorithm. Furthermore, an in vivo motion trace was obtained from a healthy volunteer. The obtained eye motion trace clearly shows the three main types of fixational eye movements. Lastly, the obtained eye motion trace was used to correct for the eye motion in consecutively obtained subsampled frames to produce an averaged confocal image correct for motion artefacts.

  12. Direct lexical control of eye movements in reading: Evidence from a survival analysis of fixation durations

    Science.gov (United States)

    Reingold, Eyal M.; Reichle, Erik D.; Glaholt, Mackenzie G.; Sheridan, Heather

    2013-01-01

    Participants’ eye movements were monitored in an experiment that manipulated the frequency of target words (high vs. low) as well as their availability for parafoveal processing during fixations on the pre-target word (valid vs. invalid preview). The influence of the word-frequency by preview validity manipulation on the distributions of first fixation duration was examined by using ex-Gaussian fitting as well as a novel survival analysis technique which provided precise estimates of the timing of the first discernible influence of word frequency on first fixation duration. Using this technique, we found a significant influence of word frequency on fixation duration in normal reading (valid preview) as early as 145 ms from the start of fixation. We also demonstrated an equally rapid non-lexical influence on first fixation duration as a function of initial landing position (location) on target words. The time-course of frequency effects, but not location effects was strongly influenced by preview validity, demonstrating the crucial role of parafoveal processing in enabling direct lexical control of reading fixation times. Implications for models of eye-movement control are discussed. PMID:22542804

  13. The right look for the job: decoding cognitive processes involved in the task from spatial eye-movement patterns.

    Science.gov (United States)

    Król, Magdalena Ewa; Król, Michał

    2018-02-20

    The aim of the study was not only to demonstrate whether eye-movement-based task decoding was possible but also to investigate whether eye-movement patterns can be used to identify cognitive processes behind the tasks. We compared eye-movement patterns elicited under different task conditions, with tasks differing systematically with regard to the types of cognitive processes involved in solving them. We used four tasks, differing along two dimensions: spatial (global vs. local) processing (Navon, Cognit Psychol, 9(3):353-383 1977) and semantic (deep vs. shallow) processing (Craik and Lockhart, J Verbal Learn Verbal Behav, 11(6):671-684 1972). We used eye-movement patterns obtained from two time periods: fixation cross preceding the target stimulus and the target stimulus. We found significant effects of both spatial and semantic processing, but in case of the latter, the effect might be an artefact of insufficient task control. We found above chance task classification accuracy for both time periods: 51.4% for the period of stimulus presentation and 34.8% for the period of fixation cross presentation. Therefore, we show that task can be to some extent decoded from the preparatory eye-movements before the stimulus is displayed. This suggests that anticipatory eye-movements reflect the visual scanning strategy employed for the task at hand. Finally, this study also demonstrates that decoding is possible even from very scant eye-movement data similar to Coco and Keller, J Vis 14(3):11-11 (2014). This means that task decoding is not limited to tasks that naturally take longer to perform and yield multi-second eye-movement recordings.

  14. Fixation Characteristics of Severe Amblyopia Subtypes: Which One is Worse?

    Science.gov (United States)

    Koylu, Mehmet Talay; Ozge, Gokhan; Kucukevcilioglu, Murat; Mutlu, Fatih Mehmet; Ceylan, Osman Melih; Akıncıoglu, Dorukcan; Ayyıldız, Onder

    2017-01-01

    To determine differences in macular sensitivity and fixation patterns in different subtypes of severe amblyopia. This case-control study enrolled a total of 73 male adults, including 18 with pure strabismic severe amblyopia, 19 with pure anisometropic severe amblyopia, 18 with mixed (strabismic plus anizometropic) severe amblyopia, and 18 healthy controls. MP-1 microperimetry was used to evaluate macular sensitivity, location of fixation, and stability of fixation. Mean macular sensitivity, stability of fixation, and location of fixation were significantly worse in all amblyopia subtypes when compared with healthy controls. Intergroup comparisons between amblyopia subtypes revealed that mean macular sensitivity, stability of fixation, and location of fixation were significantly worse in pure strabismic and mixed amblyopic eyes when compared with pure anisometropic amblyopic eyes. Strabismus seems to be a worse prognostic factor in severe amblyopia than anisometropia in terms of fixation characteristics and retinal sensitivity.

  15. Intuitive Face Judgments Rely on Holistic Eye Movement Pattern.

    Science.gov (United States)

    Mega, Laura F; Volz, Kirsten G

    2017-01-01

    Non-verbal signals such as facial expressions are of paramount importance for social encounters. Their perception predominantly occurs without conscious awareness and is effortlessly integrated into social interactions. In other words, face perception is intuitive. Contrary to classical intuition tasks, this work investigates intuitive processes in the realm of every-day type social judgments. Two differently instructed groups of participants judged the authenticity of emotional facial expressions, while their eye movements were recorded: an 'intuitive group,' instructed to rely on their "gut feeling" for the authenticity judgments, and a 'deliberative group,' instructed to make their judgments after careful analysis of the face. Pixel-wise statistical maps of the resulting eye movements revealed a differential viewing pattern, wherein the intuitive judgments relied on fewer, longer and more centrally located fixations. These markers have been associated with a global/holistic viewing strategy. The holistic pattern of intuitive face judgments is in line with evidence showing that intuition is related to processing the "gestalt" of an object, rather than focusing on details. Our work thereby provides further evidence that intuitive processes are characterized by holistic perception, in an understudied and real world domain of intuition research.

  16. Eye movement during retrieval of emotional autobiographical memories.

    Science.gov (United States)

    El Haj, Mohamad; Nandrino, Jean-Louis; Antoine, Pascal; Boucart, Muriel; Lenoble, Quentin

    2017-03-01

    This study assessed whether specific eye movement patterns are observed during emotional autobiographical retrieval. Participants were asked to retrieve positive, negative and neutral memories while their scan path was recorded by an eye-tracker. Results showed that positive and negative emotional memories triggered more fixations and saccades but shorter fixation duration than neutral memories. No significant differences were observed between emotional and neutral memories for duration and amplitude of saccades. Positive and negative retrieval triggered similar eye movement (i.e., similar number of fixations and saccades, fixation duration, duration of saccades, and amplitude of saccades). Interestingly, the participants reported higher visual imagery for emotional memories than for neutral memories. The findings demonstrate similarities and differences in eye movement during retrieval of neutral and emotional memories. Eye movement during autobiographical retrieval seems to be triggered by the creation of visual mental images as the latter are indexed by autobiographical reconstruction. Copyright © 2016. Published by Elsevier B.V.

  17. Brief Report: Eye-Movement Patterns during an Embedded Figures Test in Children with ASD

    OpenAIRE

    Keehn, Brandon; Brenner, Laurie A.; Ramos, Aurora I.; Lincoln, Alan J.; Marshall, Sandra P.; Müller, Ralph-Axel

    2008-01-01

    The present study examined fixation frequency and duration during an EFT in an effort to better understand the attentional and perceptual processes by which individuals with ASD achieve accelerated EFT performance. In particular, we aimed to elucidate differences in the patterns of eye-movement in ASD and TD children, thus providing evidence relevant to the competing weak central coherence and enhanced perceptual functioning theories. Consistent with prior EFT studies, we found accelerated RT...

  18. Correlations between psychometric schizotypy, scan path length, fixations on the eyes and face recognition.

    Science.gov (United States)

    Hills, Peter J; Eaton, Elizabeth; Pake, J Michael

    2016-01-01

    Psychometric schizotypy in the general population correlates negatively with face recognition accuracy, potentially due to deficits in inhibition, social withdrawal, or eye-movement abnormalities. We report an eye-tracking face recognition study in which participants were required to match one of two faces (target and distractor) to a cue face presented immediately before. All faces could be presented with or without paraphernalia (e.g., hats, glasses, facial hair). Results showed that paraphernalia distracted participants, and that the most distracting condition was when the cue and the distractor face had paraphernalia but the target face did not, while there was no correlation between distractibility and participants' scores on the Schizotypal Personality Questionnaire (SPQ). Schizotypy was negatively correlated with proportion of time fixating on the eyes and positively correlated with not fixating on a feature. It was negatively correlated with scan path length and this variable correlated with face recognition accuracy. These results are interpreted as schizotypal traits being associated with a restricted scan path leading to face recognition deficits.

  19. EEG Negativity in Fixations Used for Gaze-Based Control: Toward Converting Intentions into Actions with an Eye-Brain-Computer Interface

    Science.gov (United States)

    Shishkin, Sergei L.; Nuzhdin, Yuri O.; Svirin, Evgeny P.; Trofimov, Alexander G.; Fedorova, Anastasia A.; Kozyrskiy, Bogdan L.; Velichkovsky, Boris M.

    2016-01-01

    We usually look at an object when we are going to manipulate it. Thus, eye tracking can be used to communicate intended actions. An effective human-machine interface, however, should be able to differentiate intentional and spontaneous eye movements. We report an electroencephalogram (EEG) marker that differentiates gaze fixations used for control from spontaneous fixations involved in visual exploration. Eight healthy participants played a game with their eye movements only. Their gaze-synchronized EEG data (fixation-related potentials, FRPs) were collected during game's control-on and control-off conditions. A slow negative wave with a maximum in the parietooccipital region was present in each participant's averaged FRPs in the control-on conditions and was absent or had much lower amplitude in the control-off condition. This wave was similar but not identical to stimulus-preceding negativity, a slow negative wave that can be observed during feedback expectation. Classification of intentional vs. spontaneous fixations was based on amplitude features from 13 EEG channels using 300 ms length segments free from electrooculogram contamination (200–500 ms relative to the fixation onset). For the first fixations in the fixation triplets required to make moves in the game, classified against control-off data, a committee of greedy classifiers provided 0.90 ± 0.07 specificity and 0.38 ± 0.14 sensitivity. Similar (slightly lower) results were obtained for the shrinkage Linear Discriminate Analysis (LDA) classifier. The second and third fixations in the triplets were classified at lower rate. We expect that, with improved feature sets and classifiers, a hybrid dwell-based Eye-Brain-Computer Interface (EBCI) can be built using the FRP difference between the intended and spontaneous fixations. If this direction of BCI development will be successful, such a multimodal interface may improve the fluency of interaction and can possibly become the basis for a new input device

  20. EEG Negativity in Fixations Used for Gaze-Based Control: Toward Converting Intentions into Actions with an Eye-Brain-Computer Interface

    Directory of Open Access Journals (Sweden)

    Sergei L. Shishkin

    2016-11-01

    Full Text Available We usually look at an object when we are going to manipulate it. Thus, eye tracking can be used to communicate intended actions. An effective human-machine interface, however, should be able to differentiate intentional and spontaneous eye movements. We report an electroencephalogram (EEG marker that differentiates gaze fixations used for control from spontaneous fixations involved in visual exploration. Eight healthy participants played a game with their eye movements only. Their gaze-synchronized EEG data (fixation-related potentials, FRPs were collected during game’s control-on and control-off conditions. A slow negative wave with a maximum in the parietooccipital region was present in each participant’s averaged FRPs in the control-on conditions and was absent or had much lower amplitude in the control-off condition. This wave was similar but not identical to stimulus-preceding negativity, a slow negative wave that can be observed during feedback expectation. Classification of intentional vs. spontaneous fixations was based on amplitude features from 13 EEG channels using 300 ms length segments free from electrooculogram contamination (200..500 ms relative to the fixation onset. For the first fixations in the fixation triplets required to make moves in the game, classified against control-off data, a committee of greedy classifiers provided 0.90 ± 0.07 specificity and 0.38 ± 0.14 sensitivity. Similar (slightly lower results were obtained for the shrinkage LDA classifier. The second and third fixations in the triplets were classified at lower rate. We expect that, with improved feature sets and classifiers, a hybrid dwell-based Eye-Brain-Computer Interface (EBCI can be built using the FRP difference between the intended and spontaneous fixations. If this direction of BCI development will be successful, such a multimodal interface may improve the fluency of interaction and can possibly become the basis for a new input device for

  1. Transient improvements in fixational stability in strabismic amblyopes following bifoveal fixation and reduced interocular suppression.

    Science.gov (United States)

    Raveendran, Rajkumar Nallour; Babu, Raiju J; Hess, Robert F; Bobier, William R

    2014-03-01

    To test the hypothesis that fixational stability of the amblyopic eye in strabismics will improve when viewing provides both bifoveal fixation and reduced inter-ocular suppression by reducing the contrast to the fellow eye. Seven strabismic amblyopes (Age: 29.2 ± 9 years; five esotropes and two exotropes) showing clinical characteristics of central suppression were recruited. Interocular suppression was measured by a global motion task. For each participant, a balance point was determined which defined contrast levels for each eye where binocular combination was optimal (interocular suppression minimal). When the balance point could not be determined, this participant was excluded. Bifoveal fixation was established by ocular alignment using a haploscope. Participants dichoptically viewed similar targets (a cross of 2.3° surrounded by a square of 11.3°) at 40 cm. Target contrasts presented to each eye were either high contrast (100% to both eyes) or balanced contrast (attenuated contrast in the fellow fixing eye). Fixation stability was measured over a 5 min period and quantified using bivariate contour ellipse areas in four different binocular conditions; unaligned/high contrast, unaligned/balance point, aligned/high contrast and aligned/balance point. Fixation stability was also measured in six control subjects (Age: 25.3 ± 4 years). Bifoveal fixation in the strabismics was transient (58.15 ± 15.7 s). Accordingly, fixational stability was analysed over the first 30 s using repeated measures anova. Post hoc analysis revealed that for the amblyopic subjects, the fixational stability of the amblyopic eye was significantly improved in aligned/high contrast (p = 0.01) and aligned/balance point (p suppression. However, once initiated, bifoveal fixation is transient with the strabismic eye drifting away from foveal alignment, thereby increasing the angle of strabismus. © 2014 The Authors Ophthalmic & Physiological Optics © 2014 The College of Optometrists.

  2. Intuitive Face Judgments Rely on Holistic Eye Movement Pattern

    Directory of Open Access Journals (Sweden)

    Laura F. Mega

    2017-06-01

    Full Text Available Non-verbal signals such as facial expressions are of paramount importance for social encounters. Their perception predominantly occurs without conscious awareness and is effortlessly integrated into social interactions. In other words, face perception is intuitive. Contrary to classical intuition tasks, this work investigates intuitive processes in the realm of every-day type social judgments. Two differently instructed groups of participants judged the authenticity of emotional facial expressions, while their eye movements were recorded: an ‘intuitive group,’ instructed to rely on their “gut feeling” for the authenticity judgments, and a ‘deliberative group,’ instructed to make their judgments after careful analysis of the face. Pixel-wise statistical maps of the resulting eye movements revealed a differential viewing pattern, wherein the intuitive judgments relied on fewer, longer and more centrally located fixations. These markers have been associated with a global/holistic viewing strategy. The holistic pattern of intuitive face judgments is in line with evidence showing that intuition is related to processing the “gestalt” of an object, rather than focusing on details. Our work thereby provides further evidence that intuitive processes are characterized by holistic perception, in an understudied and real world domain of intuition research.

  3. Magnifying visual target information and the role of eye movements in motor sequence learning.

    Science.gov (United States)

    Massing, Matthias; Blandin, Yannick; Panzer, Stefan

    2016-01-01

    An experiment investigated the influence of eye movements on learning a simple motor sequence task when the visual display was magnified. The task was to reproduce a 1300 ms spatial-temporal pattern of elbow flexions and extensions. The spatial-temporal pattern was displayed in front of the participants. Participants were randomly assigned to four groups differing on eye movements (free to use their eyes/instructed to fixate) and the visual display (small/magnified). All participants had to perform a pre-test, an acquisition phase, a delayed retention test, and a transfer test. The results indicated that participants in each practice condition increased their performance during acquisition. The participants who were permitted to use their eyes in the magnified visual display outperformed those who were instructed to fixate on the magnified visual display. When a small visual display was used, the instruction to fixate induced no performance decrements compared to participants who were permitted to use their eyes during acquisition. The findings demonstrated that a spatial-temporal pattern can be learned without eye movements, but being permitting to use eye movements facilitates the response production when the visual angle is increased. Copyright © 2015 Elsevier B.V. All rights reserved.

  4. Simulation of airbag impact on eyes with different axial lengths after transsclerally fixated posterior chamber intraocular lens by using finite element analysis

    Directory of Open Access Journals (Sweden)

    Huang J

    2015-02-01

    Full Text Available Jane Huang,1 Eiichi Uchio,1 Satoru Goto2 1Department of Ophthalmology, Fukuoka University School of Medicine, Fukuoka, 2Nihon ESI KK Technical Division, Tokyo, Japan Purpose: To determine the biomechanical response of an impacting airbag on eyes with different axial lengths with transsclerally fixated posterior chamber intraocular lens (PC IOL.Materials and methods: Simulations in a model human eye were performed with a computer using a finite element analysis program created by Nihon, ESI Group. The airbag was set to be deployed at five different velocities and to impact on eyes with three different axial lengths. These eyes were set to have transsclerally fixated PC IOL by a 10-0 polypropylene possessing a tensile force limit of 0.16 N according to the United States Pharmacopeia XXII.Results: The corneoscleral opening was observed at a speed of 40 m/second or more in all model eyes. Eyes with the longest axial length of 25.85 mm had the greatest extent of deformity at any given impact velocity. The impact force exceeded the tensile force of 10-0 polypropylene at an impact velocity of 60 m/second in all eyes, causing breakage of the suture. Conclusion: Eyes with transsclerally fixated PC IOL could rupture from airbag impact at high velocities. Eyes with long axial lengths experienced a greater deformity upon airbag impact due to a thinner eye wall. Further basic research on the biomechanical response for assessing eye injuries could help in developing a better airbag and in the further understanding of ocular traumas. Keywords: airbag, ocular trauma, computer simulation, transsclerally fixated posterior chamber intraocular lens, finite element analysis

  5. Distinct eye movement patterns enhance dynamic visual acuity

    Science.gov (United States)

    Palidis, Dimitrios J.; Wyder-Hodge, Pearson A.; Fooken, Jolande; Spering, Miriam

    2017-01-01

    Dynamic visual acuity (DVA) is the ability to resolve fine spatial detail in dynamic objects during head fixation, or in static objects during head or body rotation. This ability is important for many activities such as ball sports, and a close relation has been shown between DVA and sports expertise. DVA tasks involve eye movements, yet, it is unclear which aspects of eye movements contribute to successful performance. Here we examined the relation between DVA and the kinematics of smooth pursuit and saccadic eye movements in a cohort of 23 varsity baseball players. In a computerized dynamic-object DVA test, observers reported the location of the gap in a small Landolt-C ring moving at various speeds while eye movements were recorded. Smooth pursuit kinematics—eye latency, acceleration, velocity gain, position error—and the direction and amplitude of saccadic eye movements were linked to perceptual performance. Results reveal that distinct eye movement patterns—minimizing eye position error, tracking smoothly, and inhibiting reverse saccades—were related to dynamic visual acuity. The close link between eye movement quality and DVA performance has important implications for the development of perceptual training programs to improve DVA. PMID:28187157

  6. An eye tracking study of bloodstain pattern analysts during pattern classification.

    Science.gov (United States)

    Arthur, R M; Hoogenboom, J; Green, R D; Taylor, M C; de Bruin, K G

    2018-05-01

    Bloodstain pattern analysis (BPA) is the forensic discipline concerned with the classification and interpretation of bloodstains and bloodstain patterns at the crime scene. At present, it is unclear exactly which stain or pattern properties and their associated values are most relevant to analysts when classifying a bloodstain pattern. Eye tracking technology has been widely used to investigate human perception and cognition. Its application to forensics, however, is limited. This is the first study to use eye tracking as a tool for gaining access to the mindset of the bloodstain pattern expert. An eye tracking method was used to follow the gaze of 24 bloodstain pattern analysts during an assigned task of classifying a laboratory-generated test bloodstain pattern. With the aid of an automated image-processing methodology, the properties of selected features of the pattern were quantified leading to the delineation of areas of interest (AOIs). Eye tracking data were collected for each AOI and combined with verbal statements made by analysts after the classification task to determine the critical range of values for relevant diagnostic features. Eye-tracking data indicated that there were four main regions of the pattern that analysts were most interested in. Within each region, individual elements or groups of elements that exhibited features associated with directionality, size, colour and shape appeared to capture the most interest of analysts during the classification task. The study showed that the eye movements of trained bloodstain pattern experts and their verbal descriptions of a pattern were well correlated.

  7. Eye gaze during comprehension of American Sign Language by native and beginning signers.

    Science.gov (United States)

    Emmorey, Karen; Thompson, Robin; Colvin, Rachael

    2009-01-01

    An eye-tracking experiment investigated where deaf native signers (N = 9) and hearing beginning signers (N = 10) look while comprehending a short narrative and a spatial description in American Sign Language produced live by a fluent signer. Both groups fixated primarily on the signer's face (more than 80% of the time) but differed with respect to fixation location. Beginning signers fixated on or near the signer's mouth, perhaps to better perceive English mouthing, whereas native signers tended to fixate on or near the eyes. Beginning signers shifted gaze away from the signer's face more frequently than native signers, but the pattern of gaze shifts was similar for both groups. When a shift in gaze occurred, the sign narrator was almost always looking at his or her hands and was most often producing a classifier construction. We conclude that joint visual attention and attention to mouthing (for beginning signers), rather than linguistic complexity or processing load, affect gaze fixation patterns during sign language comprehension.

  8. Assessment of a new hydrophilic acrylic supplementary IOL for sulcus fixation in pseudophakic cadaver eyes

    Science.gov (United States)

    Reiter, N; Werner, L; Guan, J; Li, J; Tsaousis, K T; Mamalis, N; Srinivasan, S

    2017-01-01

    Purpose Management of refractive errors after cataract surgery includes spectacles or contact lens, secondary laser vision correction, intraocular lens (IOL) exchange, or piggyback lens implantation. We evaluated for the first time a single-piece hydrophilic acrylic IOL designed for supplementary sulcus fixation in postmortem pseudophakic human eyes. Methods Pseudophakic human cadaver eyes were imaged by anterior segment optical coherence tomography (AS-OCT) to assess position of the primary IOL. Eyes were prepared as per the Miyake-Apple technique. The supplementary IOL (Medicontur A4 Addon IOL family) was then inserted into the ciliary sulcus. AS-OCT and photographs from anterior and posterior views were used to assess IOL centration, tilt, and interlenticular distance from the primary IOL. Results Data were obtained from 12 eyes having primary IOLs of varying materials and designs in the bag and representing different sizes of eyes and severity of Soemmering's ring formation. The A4 Addon IOL was successfully inserted into the ciliary sulcus and was well centered in all cases. Four cases of tilt were observed on AS-OCT: three with mild tilt due to pre-existing zonular dehiscence, and one due to a localized area of Soemmering's ring formation. Interlenticular distance ranged from 0.34 to 1.24 mm and was not dependent on severity of Soemmering's ring or type of primary IOL. Conclusions The A4 Addon IOL was designed for sulcus fixation as a supplementary lens, with a large diameter, a square-shaped optic, four smooth loop haptics, and a convex–concave optical surface. It exhibited appropriate centration and interlenticular distance with different primary in-the-bag IOLs. PMID:28106890

  9. Seasonal patterns of periphyton nitrogen fixation in calcareous wetlands

    Science.gov (United States)

    Liao, X.; Inglett, P.

    2011-12-01

    Periphyton mats are an ecologically important component of the Everglades ecosystem and plays various vital ecological functions. However, nitrogen fixation of periphyton, has received little attention throughout much of the Everglades system. The objective of this study was to characterize the seasonal pattern of periphyton N2 fixation in the Hole-in-the-Donut (HID) of Florida Everglades, where farmed marl prairie wetlands have been restored through complete soil removal (CSR) to reduce nutrient levels. Two restored areas (i.e., cleared in 2000 and 2003) and a reference (natural and unfarmed) marl prairie wetland sites were selected in the HID. Seven times of sampling were performed across the wet and dry season during the 2010 and 2011. The annual fixed nitrogen was approximately 0.4gN m-2 yr-1 in the restored sites which was higher in the reference site (~0.2gN m-2 yr-1). All the three sites showed similar seasonal patterns of N2 fixation that is higher values were observed in the wet season; but the peak value was one month later in reference sits (i.e., September) comparing to the restored areas (i.e., July). The peak of periphyton AR rates in the 2000- and 2003-restored areas appeared in July (i.e., wet season) within the range of 20-79 nmols g-1dw h-1 and 31-53nmols g-1dw h-1, respectively. In contrast, the peak of reference site was observed in September with the range of 2-5 nmols g-1dw h-1. Stable N isotopic ratios (i.e., δ15N) also varied with time but didn't show consistent seasonal pattern as nitrogen fixation. N2 fixation positively correlated with periphyton total phosphorus (TP) and negatively correlated with total nitrogen and phosphorus molar ratios (TN:TP), indicating that N2 fixation would be a indicator of nutrient limitation. In general, δ15N was negatively correlated with nitrogenase activity but the correlation became weakened in the wet season, especially in the flooded July and September, which would be explained by other environmental

  10. Intrascleral IOL Fixation.

    Science.gov (United States)

    Jacob, Soosan

    2017-01-01

    Intrascleral sutureless intraocular lens (IOL) fixation utilizes direct haptic fixation within the sclera in eyes with deficient capsular support. This has advantages of long-term stability, good control of tilt and decentration, and lesser pseudophakodonesis. This review summarizes various techniques for intrascleral haptic fixation, results, complications, adaptations in special situations, modifications of the technique, combination surgeries, and intrascleral capsular bag fixation techniques (glued capsular hook). Copyright 2017 Asia-Pacific Academy of Ophthalmology.

  11. Retropupillary Fixation of Iris-Claw Intraocular Lens for Aphakic Eyes in Children.

    Directory of Open Access Journals (Sweden)

    Martina Brandner

    Full Text Available To report outcome, complications and safety of retropupillary fixated iris-claw intraocular lenses in a pediatric population.Retrospective study.Ten consecutive pediatric patients (15 eyes underwent placement of retropupillary fixated iris-claw intraocular lenses between October 2007 and July 2013 at the Department of Ophthalmology, Medical University Graz and General Hospital Klagenfurt, Austria. Postoperative visual acuity and complications were analyzed.Median final best-corrected visual acuity improved by 0.12 logMAR from preoperative baseline. Mean postoperative spherical equivalent was -0.05 ± 1.76 D. No serious complications were observed intra- or postoperatively during the entire follow-up period of up to 40 months. One patient experienced a haptic disenclavation with IOL subluxation immediately after a car accident.Our study demonstrates that iris-claw intraocular lens implantation behind the iris is safe in children with lack of capsular support and yields excellent visual outcome with low complication rate.

  12. Retropupillary Fixation of Iris-Claw Intraocular Lens for Aphakic Eyes in Children

    Science.gov (United States)

    Brandner, Martina; Thaler-Saliba, Sarah; Plainer, Sophie; Vidic, Bertram; El-Shabrawi, Yosuf; Ardjomand, Navid

    2015-01-01

    Purpose To report outcome, complications and safety of retropupillary fixated iris-claw intraocular lenses in a pediatric population. Design Retrospective study. Patients and Methods Ten consecutive pediatric patients (15 eyes) underwent placement of retropupillary fixated iris-claw intraocular lenses between October 2007 and July 2013 at the Department of Ophthalmology, Medical University Graz and General Hospital Klagenfurt, Austria. Postoperative visual acuity and complications were analyzed. Results Median final best-corrected visual acuity improved by 0.12 logMAR from preoperative baseline. Mean postoperative spherical equivalent was -0.05 ± 1.76 D. No serious complications were observed intra- or postoperatively during the entire follow-up period of up to 40 months. One patient experienced a haptic disenclavation with IOL subluxation immediately after a car accident. Conclusion Our study demonstrates that iris-claw intraocular lens implantation behind the iris is safe in children with lack of capsular support and yields excellent visual outcome with low complication rate. PMID:26110864

  13. Fixation distance and fixation duration to vertical road signs.

    Science.gov (United States)

    Costa, Marco; Simone, Andrea; Vignali, Valeria; Lantieri, Claudio; Palena, Nicola

    2018-05-01

    The distance of first-fixation to vertical road signs was assessed in 22 participants while driving a route of 8.34 km. Fixations to road signs were recorded by a mobile eye-movement-tracking device synchronized to GPS and kinematic data. The route included 75 road signs. First-fixation distance and fixation duration distributions were positively skewed. Median distance of first-fixation was 51 m. Median fixation duration was 137 ms with a modal value of 66 ms. First-fixation distance was linearly related to speed and fixation duration. Road signs were gazed at a much closer distance than their visibility distance. In a second study a staircase procedure was used to test the presentation-time threshold that lead to a 75% accuracy in road sign identification. The threshold was 35 ms, showing that short fixations to a road signs could lead to a correct identification. Copyright © 2018 Elsevier Ltd. All rights reserved.

  14. Rett syndrome: basic features of visual processing-a pilot study of eye-tracking.

    Science.gov (United States)

    Djukic, Aleksandra; Valicenti McDermott, Maria; Mavrommatis, Kathleen; Martins, Cristina L

    2012-07-01

    Consistently observed "strong eye gaze" has not been validated as a means of communication in girls with Rett syndrome, ubiquitously affected by apraxia, unable to reply either verbally or manually to questions during formal psychologic assessment. We examined nonverbal cognitive abilities and basic features of visual processing (visual discrimination attention/memory) by analyzing patterns of visual fixation in 44 girls with Rett syndrome, compared with typical control subjects. To determine features of visual fixation patterns, multiple pictures (with the location of the salient and presence/absence of novel stimuli as variables) were presented on the screen of a TS120 eye-tracker. Of the 44, 35 (80%) calibrated and exhibited meaningful patterns of visual fixation. They looked longer at salient stimuli (cartoon, 2.8 ± 2 seconds S.D., vs shape, 0.9 ± 1.2 seconds S.D.; P = 0.02), regardless of their position on the screen. They recognized novel stimuli, decreasing the fixation time on the central image when another image appeared on the periphery of the slide (2.7 ± 1 seconds S.D. vs 1.8 ± 1 seconds S.D., P = 0.002). Eye-tracking provides a feasible method for cognitive assessment and new insights into the "hidden" abilities of individuals with Rett syndrome. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Identification system by eye retinal pattern

    International Nuclear Information System (INIS)

    Sunagawa, Takahisa; Shibata, Susumu

    1987-01-01

    Identification system by eye retinal pattern is introduced from the view-point of history of R and D, measurement, apparatus, evaluation tests, safety and application. According to our evaluation tests, enrolling time is approximately less than 1 min, verification time is a few seconds and false accept rate is 0 %. Evaluation tests at Sandia National Laboratories in USA show the comparison data of false accept rates such as 0 % for eye retinal pattern, 10.5 % for finger-print, 5.8 % for signature dynamics and 17.7 % for speaker voice. The identification system by eye retinal pattern has only three applications in Japan, but there has been a number of experience in USA. This fact suggests that the system will become an important means for physical protections not only in nuclear field but also in other industrial fields in Japan. (author)

  16. Which Eye Tracker is Right for Your Research Performance Evaluation of Several Cost Variant Eye Trackers

    Science.gov (United States)

    2016-09-19

    utilized to study a diverse number of topics such as the patterns of fixations and saccades while reading text (e.g., Rayner, 1998), the workload of...of their accessibility to our laboratory and because they represent a diverse set of relative price points, from low (Eye Tribe Tracker, Tobii EyeX...see Figure 1 for the layout of those systems). At both workstations, task stimuli were presented to observers on 48.26 cm Samsung SyncMaster 940Bx

  17. Biometric recognition via fixation density maps

    Science.gov (United States)

    Rigas, Ioannis; Komogortsev, Oleg V.

    2014-05-01

    This work introduces and evaluates a novel eye movement-driven biometric approach that employs eye fixation density maps for person identification. The proposed feature offers a dynamic representation of the biometric identity, storing rich information regarding the behavioral and physical eye movement characteristics of the individuals. The innate ability of fixation density maps to capture the spatial layout of the eye movements in conjunction with their probabilistic nature makes them a particularly suitable option as an eye movement biometrical trait in cases when free-viewing stimuli is presented. In order to demonstrate the effectiveness of the proposed approach, the method is evaluated on three different datasets containing a wide gamut of stimuli types, such as static images, video and text segments. The obtained results indicate a minimum EER (Equal Error Rate) of 18.3 %, revealing the perspectives on the utilization of fixation density maps as an enhancing biometrical cue during identification scenarios in dynamic visual environments.

  18. Eying the future: Eye movement in past and future thinking.

    Science.gov (United States)

    El Haj, Mohamad; Lenoble, Quentin

    2017-06-07

    We investigated eye movement during past and future thinking. Participants were invited to retrieve past events and to imagine future events while their scan path was recorded by an eye-tracker. Past thinking triggered more fixation (p thinking. Past and future thinking triggered a similar duration of fixations and saccades, as well as a similar amplitude of saccades. Interestingly, participants rated past thinking as more vivid than future thinking (p thinking seems to be accompanied by an increased number of fixations and saccades. Fixations and saccades in past thinking can be interpreted as an attempt by the visual system to find (through saccades) and activate (through fixations) stored memory representations. The same interpretation can be applied to future thinking as this ability requires activation of past experiences. However, future thinking triggers fewer fixations and saccades than past thinking: this may be due to its decreased demand on visual imagery, but could also be related to a potentially deleterious effect of eye movements on spatial imagery required for future thinking. Copyright © 2017 Elsevier Ltd. All rights reserved.

  19. Smaller Fixation Target Size Is Associated with More Stable Fixation and Less Variance in Threshold Sensitivity.

    Directory of Open Access Journals (Sweden)

    Kazunori Hirasawa

    Full Text Available The aims of this randomized observational case control study were to quantify fixation behavior during standard automated perimetry (SAP with different fixation targets and to evaluate the relationship between fixation behavior and threshold variability at each test point in healthy young participants experienced with perimetry. SAP was performed on the right eyes of 29 participants using the Octopus 900 perimeter, program 32, dynamic strategy. The fixation targets of Point, Cross, and Ring were used for SAP. Fixation behavior was recorded using a wearable eye-tracking glass. All participants underwent SAP twice with each fixation target in a random fashion. Fixation behavior was quantified by calculating the bivariate contour ellipse area (BCEA and the frequency of deviation from the fixation target. The BCEAs (deg2 of Point, Cross, and Ring targets were 1.11, 1.46, and 2.02, respectively. In all cases, BCEA increased significantly with increasing fixation target size (p < 0.05. The logarithmic value of BCEA demonstrated the same tendency (p < 0.05. A positive correlation was identified between fixation behavior and threshold variability for the Point and Cross targets (ρ = 0.413-0.534, p < 0.05. Fixation behavior increased with increasing fixation target size. Moreover, a larger fixation behavior tended to be associated with a higher threshold variability. A small fixation target is recommended during the visual field test.

  20. Eye movements during object recognition in visual agnosia.

    Science.gov (United States)

    Charles Leek, E; Patterson, Candy; Paul, Matthew A; Rafal, Robert; Cristino, Filipe

    2012-07-01

    This paper reports the first ever detailed study about eye movement patterns during single object recognition in visual agnosia. Eye movements were recorded in a patient with an integrative agnosic deficit during two recognition tasks: common object naming and novel object recognition memory. The patient showed normal directional biases in saccades and fixation dwell times in both tasks and was as likely as controls to fixate within object bounding contour regardless of recognition accuracy. In contrast, following initial saccades of similar amplitude to controls, the patient showed a bias for short saccades. In object naming, but not in recognition memory, the similarity of the spatial distributions of patient and control fixations was modulated by recognition accuracy. The study provides new evidence about how eye movements can be used to elucidate the functional impairments underlying object recognition deficits. We argue that the results reflect a breakdown in normal functional processes involved in the integration of shape information across object structure during the visual perception of shape. Copyright © 2012 Elsevier Ltd. All rights reserved.

  1. Prediction of Human Eye Fixations using Symmetry

    OpenAIRE

    Kootstra, Gert; Schomaker, Lambert R. B.

    2009-01-01

    Humans are very sensitive to symmetry in visual patterns. Reaction time experiments show that symmetry is detected and recognized very rapidly. This suggests that symmetry is a highly salient feature. Existing computational models of saliency, however, have mainly focused on contrast as a measure of saliency. In this paper, we discuss local symmetry as a measure of saliency. We propose a number of symmetry models and perform an eye-tracking study with human participants viewing photographic i...

  2. Comparing search patterns in digital breast tomosynthesis and full-field digital mammography: an eye tracking study.

    Science.gov (United States)

    Aizenman, Avi; Drew, Trafton; Ehinger, Krista A; Georgian-Smith, Dianne; Wolfe, Jeremy M

    2017-10-01

    As a promising imaging modality, digital breast tomosynthesis (DBT) leads to better diagnostic performance than traditional full-field digital mammograms (FFDM) alone. DBT allows different planes of the breast to be visualized, reducing occlusion from overlapping tissue. Although DBT is gaining popularity, best practices for search strategies in this medium are unclear. Eye tracking allowed us to describe search patterns adopted by radiologists searching DBT and FFDM images. Eleven radiologists examined eight DBT and FFDM cases. Observers marked suspicious masses with mouse clicks. Eye position was recorded at 1000 Hz and was coregistered with slice/depth plane as the radiologist scrolled through the DBT images, allowing a 3-D representation of eye position. Hit rate for masses was higher for tomography cases than 2-D cases and DBT led to lower false positive rates. However, search duration was much longer for DBT cases than FFDM. DBT was associated with longer fixations but similar saccadic amplitude compared with FFDM. When comparing radiologists' eye movements to a previous study, which tracked eye movements as radiologists read chest CT, we found DBT viewers did not align with previously identified "driller" or "scanner" strategies, although their search strategy most closely aligns with a type of vigorous drilling strategy.

  3. Understanding eye movements in face recognition using hidden Markov models.

    Science.gov (United States)

    Chuk, Tim; Chan, Antoni B; Hsiao, Janet H

    2014-09-16

    We use a hidden Markov model (HMM) based approach to analyze eye movement data in face recognition. HMMs are statistical models that are specialized in handling time-series data. We conducted a face recognition task with Asian participants, and model each participant's eye movement pattern with an HMM, which summarized the participant's scan paths in face recognition with both regions of interest and the transition probabilities among them. By clustering these HMMs, we showed that participants' eye movements could be categorized into holistic or analytic patterns, demonstrating significant individual differences even within the same culture. Participants with the analytic pattern had longer response times, but did not differ significantly in recognition accuracy from those with the holistic pattern. We also found that correct and wrong recognitions were associated with distinctive eye movement patterns; the difference between the two patterns lies in the transitions rather than locations of the fixations alone. © 2014 ARVO.

  4. Immaturity of Visual Fixations in Dyslexic Children.

    Directory of Open Access Journals (Sweden)

    TIADI eBi Kuyami Guy Aimé

    2016-02-01

    Full Text Available To our knowledge, behavioral studies recording visual fixations abilities in dyslexic children are scarce. The object of this paper is to explore further the visual fixation ability in dyslexics compared to chronological age-matched and reading age-matched non-dyslexic children. Fifty-five dyslexic children from 7 to 14 years old, fifty-five chronological age-matched non-dyslexic children and fifty-five reading age-matched non-dyslexic children participated to this study. Eye movements from both eyes were recorded horizontally and vertically by a video-oculography system (EyeBrain® T2. The fixation task consisted in fixating a white-filled circle appearing in the centre of the screen for 30 seconds. Results showed that dyslexic children produced a significantly higher number of unwanted saccades than both groups of non-dyslexic children. Moreover, the number of unwanted saccades significantly decreased with age in both groups of non-dyslexic children, but not in dyslexics. Furthermore, dyslexics made more saccades during the last 15 sec of fixation period with respect to both groups of non-dyslexic children. Such poor visual fixation capability in dyslexic children could be due to impaired attention abilities, as well as to an immaturity of the cortical areas controlling the fixation system.

  5. "Far from the heart far from the eye": evidence from the Capgras delusion.

    Science.gov (United States)

    Brighetti, Gianni; Bonifacci, Paola; Borlimi, Rosita; Ottaviani, Cristina

    2007-05-01

    Capgras syndrome is characterised by the belief that a significant other has been replaced by an identical-looking impostor. These patients have no difficulties with visual recognition but fail to show a skin conductance response (SCR) to the objects of the delusion. A case of Capgras delusion (YY), specifically characterised by the absence of brain lesions, constituted a good opportunity to test the relationship between SCR hyporesponsiveness and eye movement patterns to familiar and unfamiliar faces. Visual scan path and SCR were recorded for YY and 8 controls during the presentation of family members' photographs matched with unfamiliar faces of the same sex, age, and physical likeness. Eye movement patterns were explored by selecting three specific areas of interest (AOI) involving the eyes, the mouth, and the face regions. In contrast with controls, YY showed a reduction in number and sum of fixation durations to the eyes (p.05) to familiar vs. nonfamiliar faces. SCR and fixation duration to family members' eyes were significantly correlated (r=.77) in both YY and controls. Eye region exploration seems to be related to the autonomic reactivity elicited by the affective valence of familiar faces.

  6. Detection of differential viewing patterns to erotic and non-erotic stimuli using eye-tracking methodology.

    Science.gov (United States)

    Lykins, Amy D; Meana, Marta; Kambe, Gretchen

    2006-10-01

    As a first step in the investigation of the role of visual attention in the processing of erotic stimuli, eye-tracking methodology was employed to measure eye movements during erotic scene presentation. Because eye-tracking is a novel methodology in sexuality research, we attempted to determine whether the eye-tracker could detect differences (should they exist) in visual attention to erotic and non-erotic scenes. A total of 20 men and 20 women were presented with a series of erotic and non-erotic images and tracked their eye movements during image presentation. Comparisons between erotic and non-erotic image groups showed significant differences on two of three dependent measures of visual attention (number of fixations and total time) in both men and women. As hypothesized, there was a significant Stimulus x Scene Region interaction, indicating that participants visually attended to the body more in the erotic stimuli than in the non-erotic stimuli, as evidenced by a greater number of fixations and longer total time devoted to that region. These findings provide support for the application of eye-tracking methodology as a measure of visual attentional capture in sexuality research. Future applications of this methodology to expand our knowledge of the role of cognition in sexuality are suggested.

  7. The eye-voice span during reading aloud

    Directory of Open Access Journals (Sweden)

    Jochen eLaubrock

    2015-09-01

    Full Text Available Although eye movements during reading are modulated by cognitive processing demands, they also reflect visual sampling of the input, and possibly preparation of output for speech or the inner voice. By simultaneously recording eye movements and the voice during reading aloud, we obtained an output measure that constrains the length of time spent on cognitive processing. Here we investigate the dynamics of the eye-voice span (EVS, the distance between eye and voice. We show that the EVS is regulated immediately during fixation of a word by either increasing fixation duration or programming a regressive eye movement against the reading direction. EVS size at the beginning of a fixation was positively correlated with the likelihood of regressions and refixations. Regression probability was further increased if the EVS was still large at the end of a fixation: if adjustment of fixation duration did not sufficiently reduce the EVS during a fixation, then a regression rather than a refixation followed with high probability. We further show that the EVS can help understand cognitive influences on fixation duration during reading: in mixed model analyses, the EVS was a stronger predictor of fixation durations than either word frequency or word length. The EVS modulated the influence of several other predictors on single fixation durations. For example, word-N frequency effects were larger with a large EVS, especially when word N-1 frequency was low. Finally, a comparison of single fixation durations during oral and silent reading showed that reading is governed by similar principles in both reading modes, although EVS maintenance and articulatory processing also cause some differences. In summary, the eye-voice span is regulated by adjusting fixation duration and/or by programming a regressive eye movement when the eye-voice span gets too large. Overall, the EVS appears to be directly related to updating of the working memory buffer during reading.

  8. Eye-tracking study of inanimate objects

    Directory of Open Access Journals (Sweden)

    Ković Vanja

    2009-01-01

    Full Text Available Unlike the animate objects, where participants were consistent in their looking patterns, for inanimates it was difficult to identify both consistent areas of fixations and a consistent order of fixations. Furthermore, in comparison to animate objects, in animates received significantly shorter total looking time, shorter longest looks and a smaller number of overall fixations. However, as with animates, looking patterns did not systematically differ between the naming and non-naming conditions. These results suggested that animacy, but not labelling, impacts on looking behavior in this paradigm. In the light of feature-based accounts of semantic memory organization, one could interpret these findings as suggesting that processing of the animate objects is based on the saliency/diagnosticity of their visual features (which is then reflected through participants eye-movements towards those features, whereas processing of the inanimate objects is based more on functional features (which cannot be easily captured by looking behavior in such a paradigm.

  9. Modeling fixation locations using spatial point processes.

    Science.gov (United States)

    Barthelmé, Simon; Trukenbrod, Hans; Engbert, Ralf; Wichmann, Felix

    2013-10-01

    Whenever eye movements are measured, a central part of the analysis has to do with where subjects fixate and why they fixated where they fixated. To a first approximation, a set of fixations can be viewed as a set of points in space; this implies that fixations are spatial data and that the analysis of fixation locations can be beneficially thought of as a spatial statistics problem. We argue that thinking of fixation locations as arising from point processes is a very fruitful framework for eye-movement data, helping turn qualitative questions into quantitative ones. We provide a tutorial introduction to some of the main ideas of the field of spatial statistics, focusing especially on spatial Poisson processes. We show how point processes help relate image properties to fixation locations. In particular we show how point processes naturally express the idea that image features' predictability for fixations may vary from one image to another. We review other methods of analysis used in the literature, show how they relate to point process theory, and argue that thinking in terms of point processes substantially extends the range of analyses that can be performed and clarify their interpretation.

  10. An information maximization model of eye movements

    Science.gov (United States)

    Renninger, Laura Walker; Coughlan, James; Verghese, Preeti; Malik, Jitendra

    2005-01-01

    We propose a sequential information maximization model as a general strategy for programming eye movements. The model reconstructs high-resolution visual information from a sequence of fixations, taking into account the fall-off in resolution from the fovea to the periphery. From this framework we get a simple rule for predicting fixation sequences: after each fixation, fixate next at the location that minimizes uncertainty (maximizes information) about the stimulus. By comparing our model performance to human eye movement data and to predictions from a saliency and random model, we demonstrate that our model is best at predicting fixation locations. Modeling additional biological constraints will improve the prediction of fixation sequences. Our results suggest that information maximization is a useful principle for programming eye movements.

  11. How do children deal with inconsistencies in text? An eye fixation and self-paced reading study in primary school children.

    NARCIS (Netherlands)

    van der Schoot, M.; Reijntjes, A.H.A.; van Lieshout, E.C.D.M.

    2012-01-01

    In two experiments, we investigated comprehension monitoring in 10-12 years old children differing in reading comprehension skill. The children's self-paced reading times (Experiment 1) and eye fixations and regressions (Experiment 2) were measured as they read narrative texts in which an action of

  12. What interests them in the pictures?--differences in eye-tracking between rhesus monkeys and humans.

    Science.gov (United States)

    Hu, Ying-Zhou; Jiang, Hui-Hui; Liu, Ci-Rong; Wang, Jian-Hong; Yu, Cheng-Yang; Carlson, Synnöve; Yang, Shang-Chuan; Saarinen, Veli-Matti; Rizak, Joshua D; Tian, Xiao-Guang; Tan, Hen; Chen, Zhu-Yue; Ma, Yuan-Ye; Hu, Xin-Tian

    2013-10-01

    Studies estimating eye movements have demonstrated that non-human primates have fixation patterns similar to humans at the first sight of a picture. In the current study, three sets of pictures containing monkeys, humans or both were presented to rhesus monkeys and humans. The eye movements on these pictures by the two species were recorded using a Tobii eye-tracking system. We found that monkeys paid more attention to the head and body in pictures containing monkeys, whereas both monkeys and humans paid more attention to the head in pictures containing humans. The humans always concentrated on the eyes and head in all the pictures, indicating the social role of facial cues in society. Although humans paid more attention to the hands than monkeys, both monkeys and humans were interested in the hands and what was being done with them in the pictures. This may suggest the importance and necessity of hands for survival. Finally, monkeys scored lower in eye-tracking when fixating on the pictures, as if they were less interested in looking at the screen than humans. The locations of fixation in monkeys may provide insight into the role of eye movements in an evolutionary context.

  13. Frequent Pattern Mining of Eye-Tracking Records Partitioned into Cognitive Chunks

    Directory of Open Access Journals (Sweden)

    Noriyuki Matsuda

    2014-01-01

    Full Text Available Assuming that scenes would be visually scanned by chunking information, we partitioned fixation sequences of web page viewers into chunks using isolate gaze point(s as the delimiter. Fixations were coded in terms of the segments in a 5×5 mesh imposed on the screen. The identified chunks were mostly short, consisting of one or two fixations. These were analyzed with respect to the within- and between-chunk distances in the overall records and the patterns (i.e., subsequences frequently shared among the records. Although the two types of distances were both dominated by zero- and one-block shifts, the primacy of the modal shifts was less prominent between chunks than within them. The lower primacy was compensated by the longer shifts. The patterns frequently extracted at three threshold levels were mostly simple, consisting of one or two chunks. The patterns revealed interesting properties as to segment differentiation and the directionality of the attentional shifts.

  14. Single-suture scleral fixation of subluxated foldable intraocular lenses.

    Science.gov (United States)

    Yarangumeli, Alper; Alp, Mehmet Numan; Kural, Gulcan

    2012-01-01

    To evaluate the results of single-suture scleral fixation of subluxated foldable intraocular lenses (IOL) in eyes with sufficient residual capsular support. The results of IOL repositioning by single-suture scleral fixation in 6 eyes of 6 patients with IOL subluxation were included. All subluxated IOLs were single-piece hydrophilic acrylic. Subluxation resulted from posterior capsule tears in 3 eyes, zonular dialyses in 2 eyes, and zonular dialysis with a capsulorhexis tear in 1 eye. A similar technique was used in all eyes in which one haptic was externalized through a superior clear corneal incision and tied with a Pair-PAK 10-0 polypropylene suture, and was finally retracted and fixated behind the iris close to the ciliary sulcus at the 12:00 meridian. All patients were followed up for at least 6 months. Best-corrected visual acuities ranged between finger counting and 20/70 (mean logMAR 1.02±0.64) preoperatively, and between 20/100 and 20/20 (mean logMAR 0.22±0.26) at the final postoperative visit. All IOLs remained centered and no significant postoperative complications were encountered except for an IOL tilt which resulted in a considerable oblique astigmatism in one eye. Subluxated foldable IOLs may safely be repositioned and secured with a single scleral fixation suture in selected cases with adequate amount of capsular remnants.

  15. Cross-Coupled Eye Movement Supports Neural Origin of Pattern Strabismus

    Science.gov (United States)

    Ghasia, Fatema F.; Shaikh, Aasef G.; Jacobs, Jonathan; Walker, Mark F.

    2015-01-01

    Purpose. Pattern strabismus describes vertically incomitant horizontal strabismus. Conventional theories emphasized the role of orbital etiologies, such as abnormal fundus torsion and misaligned orbital pulleys as a cause of the pattern strabismus. Experiments in animal models, however, suggested the role of abnormal cross-connections between the neural circuits. We quantitatively assessed eye movements in patients with pattern strabismus with a goal to delineate the role of neural circuits versus orbital etiologies. Methods. We measured saccadic eye movements with high-precision video-oculography in 14 subjects with pattern strabismus, 5 with comitant strabismus, and 15 healthy controls. We assessed change in eye position in the direction orthogonal to that of the desired eye movement (cross-coupled responses). We used fundus photography to quantify the fundus torsion. Results. We found cross-coupling of saccades in all patients with pattern strabismus. The cross-coupled responses were in the same direction in both eyes, but larger in the nonviewing eye. All patients had clinically apparent inferior oblique overaction with abnormal excylotorsion. There was no correlation between the amount of the fundus torsion or the grade of oblique overaction and the severity of cross-coupling. The disconjugacy in the saccade direction and amplitude in pattern strabismics did not have characteristics predicted by clinically apparent inferior oblique overaction. Conclusions. Our results validated primate models of pattern strabismus in human patients. We found no correlation between ocular torsion or oblique overaction and cross-coupling. Therefore, we could not ascribe cross-coupling exclusively to the orbital etiology. Patients with pattern strabismus could have abnormalities in the saccade generators. PMID:26024072

  16. Visual scan-path analysis with feature space transient fixation moments

    Science.gov (United States)

    Dempere-Marco, Laura; Hu, Xiao-Peng; Yang, Guang-Zhong

    2003-05-01

    The study of eye movements provides useful insight into the cognitive processes underlying visual search tasks. The analysis of the dynamics of eye movements has often been approached from a purely spatial perspective. In many cases, however, it may not be possible to define meaningful or consistent dynamics without considering the features underlying the scan paths. In this paper, the definition of the feature space has been attempted through the concept of visual similarity and non-linear low dimensional embedding, which defines a mapping from the image space into a low dimensional feature manifold that preserves the intrinsic similarity of image patterns. This has enabled the definition of perceptually meaningful features without the use of domain specific knowledge. Based on this, this paper introduces a new concept called Feature Space Transient Fixation Moments (TFM). The approach presented tackles the problem of feature space representation of visual search through the use of TFM. We demonstrate the practical values of this concept for characterizing the dynamics of eye movements in goal directed visual search tasks. We also illustrate how this model can be used to elucidate the fundamental steps involved in skilled search tasks through the evolution of transient fixation moments.

  17. Reading strategies in mild to moderate strabismic amblyopia: an eye movement investigation.

    Science.gov (United States)

    Kanonidou, Evgenia; Proudlock, Frank A; Gottlob, Irene

    2010-07-01

    PURPOSE. To investigate oculomotor strategies in strabismic amblyopia and evaluate abnormalities during monocular and binocular reading. METHODS. Eye movements were recorded with a head-mounted infrared video eye-tracker (250 Hz, amblyopia, reading is impaired, not only during monocular viewing with the amblyopic eye, but also with the nonamblyopic eye and binocularly, even though normal visual acuity pertains to the latter two conditions. The impaired reading performance is associated with differences in both the saccadic and fixational patterns, most likely as adaptation strategies to abnormal sensory experiences such as crowding and suppression.

  18. The Relation between Reading Skills and Eye Movement Patterns in Adolescent Readers: Evidence from a Regular Orthography.

    Directory of Open Access Journals (Sweden)

    Magdalena Krieber

    Full Text Available Over the past decades, the relation between reading skills and eye movement behavior has been well documented in English-speaking cohorts. As English and German differ substantially with regard to orthographic complexity (i.e. grapheme-phoneme correspondence, we aimed to delineate specific characteristics of how reading speed and reading comprehension interact with eye movements in typically developing German-speaking (Austrian adolescents. Eye movements of 22 participants (14 females; mean age = 13;6 years;months were tracked while they were performing three tasks, namely silently reading words, texts, and pseudowords. Their reading skills were determined by means of a standardized German reading speed and reading comprehension assessment (Lesegeschwindigkeits- und -verständnistest für Klassen 6-12. We found that (a reading skills were associated with various eye movement parameters in each of the three reading tasks; (b better reading skills were associated with an increased efficiency of eye movements, but were primarily linked to spatial reading parameters, such as the number of fixations per word, the total number of saccades and saccadic amplitudes; (c reading speed was a more reliable predictor for eye movement parameters than reading comprehension; (d eye movements were highly correlated across reading tasks, which indicates consistent reading performances. Contrary to findings in English-speaking cohorts, the reading skills neither consistently correlated with temporal eye movement parameters nor with the number or percentage of regressions made while performing any of the three reading tasks. These results indicate that, although reading skills are associated with eye movement patterns irrespective of language, the temporal and spatial characteristics of this association may vary with orthographic consistency.

  19. Through the Eyes of the Beholder: Simulated Eye-movement Experience ("SEE") Modulates Valence Bias in Response to Emotional Ambiguity.

    Science.gov (United States)

    Neta, Maital; Dodd, Michael D

    2018-02-01

    Although some facial expressions provide clear information about people's emotions and intentions (happy, angry), others (surprise) are ambiguous because they can signal both positive (e.g., surprise party) and negative outcomes (e.g., witnessing an accident). Without a clarifying context, surprise is interpreted as positive by some and negative by others, and this valence bias is stable across time. When compared to fearful expressions, which are consistently rated as negative, surprise and fear share similar morphological features (e.g., widened eyes) primarily in the upper part of the face. Recently, we demonstrated that the valence bias was associated with a specific pattern of eye movements (positive bias associated with faster fixation to the lower part of the face). In this follow-up, we identified two participants from our previous study who had the most positive and most negative valence bias. We used their eye movements to create a moving window such that new participants viewed faces through the eyes of one our previous participants (subjects saw only the areas of the face that were directly fixated by the original participants in the exact order they were fixated; i.e., Simulated Eye-movement Experience). The input provided by these windows modulated the valence ratings of surprise, but not fear faces. These findings suggest there are meaningful individual differences in how people process faces, and that these differences impact our emotional perceptions. Furthermore, this study is unique in its approach to examining individual differences in emotion by creating a new methodology adapted from those used primarily in the vision/attention domain. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

  20. Eye movement perimetry in glaucoma.

    Science.gov (United States)

    Trope, G E; Eizenman, M; Coyle, E

    1989-08-01

    Present-day computerized perimetry is often inaccurate and unreliable owing to the need to maintain central fixation over long periods while repressing the normal response to presentation of peripheral stimuli. We tested a new method of perimetry that does not require prolonged central fixation. During this test eye movements were encouraged on presentation of a peripheral target. Twenty-three eyes were studied with an Octopus perimeter, with a technician monitoring eye movements. The sensitivity was 100% and the specificity 23%. The low specificity was due to the technician's inability to accurately monitor small eye movements in the central 6 degrees field. If small eye movements are monitored accurately with an eye tracker, eye movement perimetry could become an alternative method to standard perimetry.

  1. Eye-movement patterns during nonsymbolic and symbolic numerical magnitude comparison and their relation to math calculation skills.

    Science.gov (United States)

    Price, Gavin R; Wilkey, Eric D; Yeo, Darren J

    2017-05-01

    A growing body of research suggests that the processing of nonsymbolic (e.g. sets of dots) and symbolic (e.g. Arabic digits) numerical magnitudes serves as a foundation for the development of math competence. Performance on magnitude comparison tasks is thought to reflect the precision of a shared cognitive representation, as evidence by the presence of a numerical ratio effect for both formats. However, little is known regarding how visuo-perceptual processes are related to the numerical ratio effect, whether they are shared across numerical formats, and whether they relate to math competence independently of performance outcomes. The present study investigates these questions in a sample of typically developing adults. Our results reveal a pattern of associations between eye-movement measures, but not their ratio effects, across formats. This suggests that ratio-specific visuo-perceptual processing during magnitude processing is different across nonsymbolic and symbolic formats. Furthermore, eye movements are related to math performance only during symbolic comparison, supporting a growing body of literature suggesting symbolic number processing is more strongly related to math outcomes than nonsymbolic magnitude processing. Finally, eye-movement patterns, specifically fixation dwell time, continue to be negatively related to math performance after controlling for task performance (i.e. error rate and reaction time) and domain general cognitive abilities (IQ), suggesting that fluent visual processing of Arabic digits plays a unique and important role in linking symbolic number processing to formal math abilities. Copyright © 2017 Elsevier B.V. All rights reserved.

  2. Keep your eyes on the ball: smooth pursuit eye movements enhance prediction of visual motion.

    Science.gov (United States)

    Spering, Miriam; Schütz, Alexander C; Braun, Doris I; Gegenfurtner, Karl R

    2011-04-01

    Success of motor behavior often depends on the ability to predict the path of moving objects. Here we asked whether tracking a visual object with smooth pursuit eye movements helps to predict its motion direction. We developed a paradigm, "eye soccer," in which observers had to either track or fixate a visual target (ball) and judge whether it would have hit or missed a stationary vertical line segment (goal). Ball and goal were presented briefly for 100-500 ms and disappeared from the screen together before the perceptual judgment was prompted. In pursuit conditions, the ball moved towards the goal; in fixation conditions, the goal moved towards the stationary ball, resulting in similar retinal stimulation during pursuit and fixation. We also tested the condition in which the goal was fixated and the ball moved. Motion direction prediction was significantly better in pursuit than in fixation trials, regardless of whether ball or goal served as fixation target. In both fixation and pursuit trials, prediction performance was better when eye movements were accurate. Performance also increased with shorter ball-goal distance and longer presentation duration. A longer trajectory did not affect performance. During pursuit, an efference copy signal might provide additional motion information, leading to the advantage in motion prediction.

  3. Eye Movement Indices in the Study of Depressive Disorder.

    Science.gov (United States)

    Li, Yu; Xu, Yangyang; Xia, Mengqing; Zhang, Tianhong; Wang, Junjie; Liu, Xu; He, Yongguang; Wang, Jijun

    2016-12-25

    Impaired cognition is one of the most common core symptoms of depressive disorder. Eye movement testing mainly reflects patients' cognitive functions, such as cognition, memory, attention, recognition, and recall. This type of testing has great potential to improve theories related to cognitive functioning in depressive episodes as well as potential in its clinical application. This study investigated whether eye movement indices of patients with unmedicated depressive disorder were abnormal or not, as well as the relationship between these indices and mental symptoms. Sixty patients with depressive disorder and sixty healthy controls (who were matched by gender, age and years of education) were recruited, and completed eye movement tests including three tasks: fixation task, saccade task and free-view task. The EyeLink desktop eye tracking system was employed to collect eye movement information, and analyze the eye movement indices of the three tasks between the two groups. (1) In the fixation task, compared to healthy controls, patients with depressive disorder showed more fixations, shorter fixation durations, more saccades and longer saccadic lengths; (2) In the saccade task, patients with depressive disorder showed longer anti-saccade latencies and smaller anti-saccade peak velocities; (3) In the free-view task, patients with depressive disorder showed fewer saccades and longer mean fixation durations; (4) Correlation analysis showed that there was a negative correlation between the pro-saccade amplitude and anxiety symptoms, and a positive correlation between the anti-saccade latency and anxiety symptoms. The depression symptoms were negatively correlated with fixation times, saccades, and saccadic paths respectively in the free-view task; while the mean fixation duration and depression symptoms showed a positive correlation. Compared to healthy controls, patients with depressive disorder showed significantly abnormal eye movement indices. In addition

  4. Eye Movements in Darkness Modulate Self-Motion Perception.

    Science.gov (United States)

    Clemens, Ivar Adrianus H; Selen, Luc P J; Pomante, Antonella; MacNeilage, Paul R; Medendorp, W Pieter

    2017-01-01

    During self-motion, humans typically move the eyes to maintain fixation on the stationary environment around them. These eye movements could in principle be used to estimate self-motion, but their impact on perception is unknown. We had participants judge self-motion during different eye-movement conditions in the absence of full-field optic flow. In a two-alternative forced choice task, participants indicated whether the second of two successive passive lateral whole-body translations was longer or shorter than the first. This task was used in two experiments. In the first ( n = 8), eye movements were constrained differently in the two translation intervals by presenting either a world-fixed or body-fixed fixation point or no fixation point at all (allowing free gaze). Results show that perceived translations were shorter with a body-fixed than a world-fixed fixation point. A linear model indicated that eye-movement signals received a weight of ∼25% for the self-motion percept. This model was independently validated in the trials without a fixation point (free gaze). In the second experiment ( n = 10), gaze was free during both translation intervals. Results show that the translation with the larger eye-movement excursion was judged more often to be larger than chance, based on an oculomotor choice probability analysis. We conclude that eye-movement signals influence self-motion perception, even in the absence of visual stimulation.

  5. On the relationship between optical variability, visual saliency, and eye fixations: a computational approach.

    Science.gov (United States)

    Garcia-Diaz, Antón; Leborán, Víctor; Fdez-Vidal, Xosé R; Pardo, Xosé M

    2012-06-12

    A hierarchical definition of optical variability is proposed that links physical magnitudes to visual saliency and yields a more reductionist interpretation than previous approaches. This definition is shown to be grounded on the classical efficient coding hypothesis. Moreover, we propose that a major goal of contextual adaptation mechanisms is to ensure the invariance of the behavior that the contribution of an image point to optical variability elicits in the visual system. This hypothesis and the necessary assumptions are tested through the comparison with human fixations and state-of-the-art approaches to saliency in three open access eye-tracking datasets, including one devoted to images with faces, as well as in a novel experiment using hyperspectral representations of surface reflectance. The results on faces yield a significant reduction of the potential strength of semantic influences compared to previous works. The results on hyperspectral images support the assumptions to estimate optical variability. As well, the proposed approach explains quantitative results related to a visual illusion observed for images of corners, which does not involve eye movements.

  6. Modulations of eye movement patterns by spatial filtering during the learning and testing phases of an old/new face recognition task.

    Science.gov (United States)

    Lemieux, Chantal L; Collin, Charles A; Nelson, Elizabeth A

    2015-02-01

    In two experiments, we examined the effects of varying the spatial frequency (SF) content of face images on eye movements during the learning and testing phases of an old/new recognition task. At both learning and testing, participants were presented with face stimuli band-pass filtered to 11 different SF bands, as well as an unfiltered baseline condition. We found that eye movements varied significantly as a function of SF. Specifically, the frequency of transitions between facial features showed a band-pass pattern, with more transitions for middle-band faces (≈5-20 cycles/face) than for low-band (≈20 cpf) ones. These findings were similar for the learning and testing phases. The distributions of transitions across facial features were similar for the middle-band, high-band, and unfiltered faces, showing a concentration on the eyes and mouth; conversely, low-band faces elicited mostly transitions involving the nose and nasion. The eye movement patterns elicited by low, middle, and high bands are similar to those previous researchers have suggested reflect holistic, configural, and featural processing, respectively. More generally, our results are compatible with the hypotheses that eye movements are functional, and that the visual system makes flexible use of visuospatial information in face processing. Finally, our finding that only middle spatial frequencies yielded the same number and distribution of fixations as unfiltered faces adds more evidence to the idea that these frequencies are especially important for face recognition, and reveals a possible mediator for the superior performance that they elicit.

  7. Relationship between eye dominance and pattern electroretinograms in normal human subjects.

    Science.gov (United States)

    Kamis, Umit; Gunduz, Kemal; Okudan, Nilsel; Gokbel, Hakki; Bodur, Sait; Tan, Uner

    2005-02-01

    The authors conducted a study in 100 non-smoker healthy normal human subjects to find a relationship between eye dominance and macular function as tested by using transient stimulus and electroretinography. Eye preference procedure was carried out using two reference points and pattern electroretinograms (PERGs) were recorded using black and white checks, each check subtending 23'. Trace averager was retriggered every 300 milliseconds (ms) with data collection time of 150 ms. The difference in PERG P50 amplitudes between right and left eyes was analyzed using Student's t test. There was no significant difference in PERG P50 amplitudes between the right and left eye dominant subjects as well as no significant differences between the right and left eyes in right eye dominants and left eye dominants, but in the left-eye dominant group the left eye PERG P50 amplitudes were significantly higher in females than males. Although pattern-reversal visual evoked potentials of healthy subjects provide electrophysiological evidence of lateralization in the nervous system, sensory eye dominance seems to have no correlation with macular function.

  8. Sutureless intrascleral intraocular lens fixation with lamellar dissection of scleral tunnel

    Directory of Open Access Journals (Sweden)

    Kawaji T

    2016-01-01

    Full Text Available Takahiro Kawaji,1,2 Tomoki Sato,2 Hidenobu Tanihara11Department of Ophthalmology, Faculty of Life Sciences, Kumamoto University, Chuo-ku, 2Sato Eye & Internal Medicine Clinic, Kumamoto, JapanPurpose: To report the results of sutureless scleral fixation of a posterior chamber intraocular lens (IOL by using our developed simple technique.Methods: We retrospectively reviewed the medical records of 48 eyes of 47 patients who underwent sutureless intrascleral IOL fixation by using our modified technique. A 25-gauge microvitreoretinal knife was used to perform sclerotomies and create limbus-parallel scleral tunnels with lamellar dissection in which the haptics were fixed.Results: The IOLs were fixed and centered well. The mean follow-up period was 26.7 months. Postoperative complications included smooth vitreous hemorrhage in four eyes (8.3%, cystoid macular edema in two eyes (4.2%, and iris capture of the IOL in two eyes (4.2%. No other complications, such as breakage of the IOL, spontaneous IOL dislocation, or retinal detachment, were detected during the follow-up period.Conclusion: The lamellar dissection of the limbus-parallel scleral tunnel can simplify the forceps-assisted introduction of the haptics into the scleral tunnel, and this technique seemed to be safe.Keywords: intraocular lenses, ophthalmologic surgical procedures, intrascleral fixation, sutureless fixation

  9. What checkers actually check: an eye tracking study of inhibitory control and working memory.

    Directory of Open Access Journals (Sweden)

    Ben Harkin

    Full Text Available Not only is compulsive checking the most common symptom in Obsessive Compulsive Disorder (OCD with an estimated prevalence of 50-80% in patients, but approximately ∼15% of the general population reveal subclinical checking tendencies that impact negatively on their performance in daily activities. Therefore, it is critical to understand how checking affects attention and memory in clinical as well as subclinical checkers. Eye fixations are commonly used as indicators for the distribution of attention but research in OCD has revealed mixed results at best.Here we report atypical eye movement patterns in subclinical checkers during an ecologically valid working memory (WM manipulation. Our key manipulation was to present an intermediate probe during the delay period of the memory task, explicitly asking for the location of a letter, which, however, had not been part of the encoding set (i.e., misleading participants. Using eye movement measures we now provide evidence that high checkers' inhibitory impairments for misleading information results in them checking the contents of WM in an atypical manner. Checkers fixate more often and for longer when misleading information is presented than non-checkers. Specifically, checkers spend more time checking stimulus locations as well as locations that had actually been empty during encoding.We conclude that these atypical eye movement patterns directly reflect internal checking of memory contents and we discuss the implications of our findings for the interpretation of behavioural and neuropsychological data. In addition our results highlight the importance of ecologically valid methodology for revealing the impact of detrimental attention and memory checking on eye movement patterns.

  10. E2F4 is required for early eye patterning.

    Science.gov (United States)

    Ruzhynsky, Vladimir A; Furimsky, Marosh; Park, David S; Wallace, Valerie A; Slack, Ruth S

    2009-01-01

    Increasingly, studies reveal novel functions for cell cycle proteins during development. Here, we investigated the role of E2F4 in eye development. E2F4-deficient mouse embryos exhibit severe early eye patterning defects, which are evident from embryonic day 11.5 and characterized by aberrant shape of the optic cup, coloboma as well as abnormal eye pigmentation. Loss of E2F4 is associated with proximal-distal patterning defects in the optic vesicle. These defects are characterized by the expansion of optic stalk marker gene expression to the optic cup and reduced expression of ventral optic cup markers. These defects are associated with a split of Shh expression domain at the ventral midline of the forebrain and expansion of the Shh activity into the ventral optic cup. Despite these patterning defects, early neuronal differentiation and Shh expression in the retina are not affected by E2F4 deletion. Overall, the results of our studies show a novel role of E2F4 in the early eye development. 2009 S. Karger AG, Basel.

  11. Hidden Markov model analysis reveals the advantage of analytic eye movement patterns in face recognition across cultures.

    Science.gov (United States)

    Chuk, Tim; Crookes, Kate; Hayward, William G; Chan, Antoni B; Hsiao, Janet H

    2017-12-01

    It remains controversial whether culture modulates eye movement behavior in face recognition. Inconsistent results have been reported regarding whether cultural differences in eye movement patterns exist, whether these differences affect recognition performance, and whether participants use similar eye movement patterns when viewing faces from different ethnicities. These inconsistencies may be due to substantial individual differences in eye movement patterns within a cultural group. Here we addressed this issue by conducting individual-level eye movement data analysis using hidden Markov models (HMMs). Each individual's eye movements were modeled with an HMM. We clustered the individual HMMs according to their similarities and discovered three common patterns in both Asian and Caucasian participants: holistic (looking mostly at the face center), left-eye-biased analytic (looking mostly at the two individual eyes in addition to the face center with a slight bias to the left eye), and right-eye-based analytic (looking mostly at the right eye in addition to the face center). The frequency of participants adopting the three patterns did not differ significantly between Asians and Caucasians, suggesting little modulation from culture. Significantly more participants (75%) showed similar eye movement patterns when viewing own- and other-race faces than different patterns. Most importantly, participants with left-eye-biased analytic patterns performed significantly better than those using either holistic or right-eye-biased analytic patterns. These results suggest that active retrieval of facial feature information through an analytic eye movement pattern may be optimal for face recognition regardless of culture. Copyright © 2017 Elsevier B.V. All rights reserved.

  12. Computing eye gaze metrics for the automatic assessment of radiographer performance during X-ray image interpretation.

    Science.gov (United States)

    McLaughlin, Laura; Bond, Raymond; Hughes, Ciara; McConnell, Jonathan; McFadden, Sonyia

    2017-09-01

    To investigate image interpretation performance by diagnostic radiography students, diagnostic radiographers and reporting radiographers by computing eye gaze metrics using eye tracking technology. Three groups of participants were studied during their interpretation of 8 digital radiographic images including the axial and appendicular skeleton, and chest (prevalence of normal images was 12.5%). A total of 464 image interpretations were collected. Participants consisted of 21 radiography students, 19 qualified radiographers and 18 qualified reporting radiographers who were further qualified to report on the musculoskeletal (MSK) system. Eye tracking data was collected using the Tobii X60 eye tracker and subsequently eye gaze metrics were computed. Voice recordings, confidence levels and diagnoses provided a clear demonstration of the image interpretation and the cognitive processes undertaken by each participant. A questionnaire afforded the participants an opportunity to offer information on their experience in image interpretation and their opinion on the eye tracking technology. Reporting radiographers demonstrated a 15% greater accuracy rate (p≤0.001), were more confident (p≤0.001) and took a mean of 2.4s longer to clinically decide on all features compared to students. Reporting radiographers also had a 15% greater accuracy rate (p≤0.001), were more confident (p≤0.001) and took longer to clinically decide on an image diagnosis (p=0.02) than radiographers. Reporting radiographers had a greater mean fixation duration (p=0.01), mean fixation count (p=0.04) and mean visit count (p=0.04) within the areas of pathology compared to students. Eye tracking patterns, presented within heat maps, were a good reflection of group expertise and search strategies. Eye gaze metrics such as time to first fixate, fixation count, fixation duration and visit count within the areas of pathology were indicative of the radiographer's competency. The accuracy and confidence of

  13. Pattern of Conjunctival Masses Seen At Guinness Eye Centre Luth ...

    African Journals Online (AJOL)

    Pattern of Conjunctival Masses Seen At Guinness Eye Centre Luth Idi-Araba. ... Open Access DOWNLOAD FULL TEXT Subscription or Fee ... 13.2% of eyes. Our study however did not confirm outdoor occupations as a risk factor for pterygium.

  14. Vertical eye position-dependence of the human vestibuloocular reflex during passive and active yaw head rotations.

    Science.gov (United States)

    Thurtell, M J; Black, R A; Halmagyi, G M; Curthoys, I S; Aw, S T

    1999-05-01

    Vertical eye position-dependence of the human vestibuloocular reflex during passive and active yaw head rotations. The effect of vertical eye-in-head position on the compensatory eye rotation response to passive and active high acceleration yaw head rotations was examined in eight normal human subjects. The stimuli consisted of brief, low amplitude (15-25 degrees ), high acceleration (4,000-6,000 degrees /s2) yaw head rotations with respect to the trunk (peak velocity was 150-350 degrees /s). Eye and head rotations were recorded in three-dimensional space using the magnetic search coil technique. The input-output kinematics of the three-dimensional vestibuloocular reflex (VOR) were assessed by finding the difference between the inverted eye velocity vector and the head velocity vector (both referenced to a head-fixed coordinate system) as a time series. During passive head impulses, the head and eye velocity axes aligned well with each other for the first 47 ms after the onset of the stimulus, regardless of vertical eye-in-head position. After the initial 47-ms period, the degree of alignment of the eye and head velocity axes was modulated by vertical eye-in-head position. When fixation was on a target 20 degrees up, the eye and head velocity axes remained well aligned with each other. However, when fixation was on targets at 0 and 20 degrees down, the eye velocity axis tilted forward relative to the head velocity axis. During active head impulses, the axis tilt became apparent within 5 ms of the onset of the stimulus. When fixation was on a target at 0 degrees, the velocity axes remained well aligned with each other. When fixation was on a target 20 degrees up, the eye velocity axis tilted backward, when fixation was on a target 20 degrees down, the eye velocity axis tilted forward. The findings show that the VOR compensates very well for head motion in the early part of the response to unpredictable high acceleration stimuli-the eye position- dependence of the

  15. Flanged Intrascleral Intraocular Lens Fixation with Double-Needle Technique.

    Science.gov (United States)

    Yamane, Shin; Sato, Shimpei; Maruyama-Inoue, Maiko; Kadonosono, Kazuaki

    2017-08-01

    To report the clinical outcomes of a new technique for transconjunctival intrascleral fixation of an intraocular lens (IOL). Prospective, noncomparative, interventional case series. One hundred eyes of 97 consecutive patients with aphakia, dislocated IOL, or subluxated crystalline lens who underwent posterior chamber sutureless implantation of an IOL were studied. Two angled incisions parallel to the limbus were made by 30-gauge thin-wall needles. Haptics of an IOL were externalized with the needles and cauterized to make a flange of the haptics. The flange of the haptics were pushed back and fixed into the scleral tunnels. Best-corrected visual acuity (VA), corneal endothelial cell density, IOL tilt, and complications were determined. The IOLs were fixed with exact centration and axial stability. The mean preoperative best-corrected VA was 0.25 logarithm of the minimum angle of resolution (logMAR) units; after surgery, it improved significantly to 0.11 logMAR, 0.09 logMAR, 0.12 logMAR, and 0.04 logMAR at 6, 12, 24, and 36 months, respectively (P IOL tilt was 3.4°±2.5°. The postoperative complications included iris capture by the IOL in 8 eyes (8%), vitreous hemorrhage in 5 eyes (5%), and cystoid macular edema in 1 eye (1%). There were no incidents of postoperative retinal detachment, endophthalmitis, or IOL dislocation. We have developed a new technique for intrascleral IOL fixation. The flanged IOL fixation technique is a simple and minimally invasive method for achieving good IOL fixation with firm haptic fixation. Copyright © 2017 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  16. Pattern of Eye Injuries in Children in Benin City, Nigeria ...

    African Journals Online (AJOL)

    Pattern of Eye Injuries in Children in Benin City, Nigeria. ... Open Access DOWNLOAD FULL TEXT ... Majority of the eye injuries were lacerations (50%). ... It is also important to educate parents and caregivers on the likely risk of injury that ...

  17. Eye Tracker Accuracy: Quantitative Evaluation of the Invisible Eye Center Location

    OpenAIRE

    Wyder, Stephan; Cattin, Philippe C.

    2017-01-01

    Purpose. We present a new method to evaluate the accuracy of an eye tracker based eye localization system. Measuring the accuracy of an eye tracker's primary intention, the estimated point of gaze, is usually done with volunteers and a set of fixation points used as ground truth. However, verifying the accuracy of the location estimate of a volunteer's eye center in 3D space is not easily possible. This is because the eye center is an intangible point hidden by the iris. Methods. We evaluate ...

  18. Induced Gamma-Band Activity and Fixational Eye Movements are Differentially Influenced by Low-and High-Level Factors in a Visual Object Classification Task

    Directory of Open Access Journals (Sweden)

    J Martinovic

    2011-04-01

    Full Text Available Until recently induced high frequency oscillatory activity (gamma-band activity; >30 Hz was considered a neural marker of cortical object representation. However, Yuval-Greenberg et al (2008; Neuron demonstrated that induced gamma-band activity (GBA in the elecetroencephalogram (EEG is susceptible to artifacts caused by miniature eye movements, which account for the major part of the signal in the crucial time window of 200-400 ms after stimulus onset. Is there an underlying cortical-induced gamma-band response that is obscured by ocular artifacts but can still be recorded with EEG? Furthermore, if object-specific modulations of induced GBA in previous studies were caused by ocular artifacts, should we instead study fixational eye movements as a response that can reflect higher-level representational processes in vision? In order to investigate this, we conducted an eye tracking experiment and an EEG experiment using the same design. Participants were asked to classify line drawings of objects or non-objects. To introduce low-level differences, their contours were defined along different directions in cardinal colour space: 1 S-cone-isolating (S, or 2 intermediate isoluminant (S and L-M, or 3 a full-colour stimulus, containing an additional achromatic component (S; L-M; L+M+S. In both experiments, behavioural performance was optimal for full-colour stimuli. In the eye tracking experiment, fixational eye movement rates 200-400 ms after stimulus onset depended on low-level factors, with no difference between objects and non-objects. In the EEG experiment, miniature eye movements were identified and removed using the saccadic filter approach. The artifact-free induced GBA exhibited a lateralised distribution, with enhancements at left and right posterior sites. Activity was higher for full-colour objects on the left, with the opposite effect observed on the right. We conclude that induced GBA can be observed in the EEG. While it showed high

  19. Visual Discomfort From Flash Afterimages of Riloid Patterns.

    Science.gov (United States)

    O'Hare, Louise

    2017-06-01

    Op-art-based stimuli have been shown to be uncomfortable, possibly due to a combination of fixational eye movements (microsaccades) and excessive cortical responses. Efforts have been made to measure illusory phenomena arising from these stimuli in the absence of microsaccades, but there has been no attempt thus far to decouple the effects of the cortical response from the effect of fixational eye movements. This study uses flash afterimages to stabilise the image on the retina and thus reduce the systematic effect of eye movements, in order to investigate the role of the brain in discomfort from op-art-based stimuli. There was a relationship between spatial frequency and the magnitude of the P300 response, showing a similar pattern to that of discomfort judgements, which suggests that there might be a role of discomfort and excessive neural responses independently from the effects of microsaccades.

  20. The saccadic flow baseline: Accounting for image-independent biases in fixation behavior.

    Science.gov (United States)

    Clarke, Alasdair D F; Stainer, Matthew J; Tatler, Benjamin W; Hunt, Amelia R

    2017-09-01

    Much effort has been made to explain eye guidance during natural scene viewing. However, a substantial component of fixation placement appears to be a set of consistent biases in eye movement behavior. We introduce the concept of saccadic flow, a generalization of the central bias that describes the image-independent conditional probability of making a saccade to (xi+1, yi+1), given a fixation at (xi, yi). We suggest that saccadic flow can be a useful prior when carrying out analyses of fixation locations, and can be used as a submodule in models of eye movements during scene viewing. We demonstrate the utility of this idea by presenting bias-weighted gaze landscapes, and show that there is a link between the likelihood of a saccade under the flow model, and the salience of the following fixation. We also present a minor improvement to our central bias model (based on using a multivariate truncated Gaussian), and investigate the leftwards and coarse-to-fine biases in scene viewing.

  1. Eye movements characteristics of Chinese dyslexic children in picture searching.

    Science.gov (United States)

    Huang, Xu; Jing, Jin; Zou, Xiao-Bing; Wang, Meng-Long; Li, Xiu-Hong; Lin, Ai-Hua

    2008-09-05

    Reading Chinese, a kind of ideogram, relies more on visual cognition. The visuospatial cognitive deficit of Chinese dyslexia is an interesting topic that has received much attention. The purpose of current research was to explore the visuopatial cognitive characteristics of Chinese dyslexic children by studying their eye movements via a picture searching test. According to the diagnostic criteria defined by ICD-10, twenty-eight dyslexic children (mean age (10.12 +/- 1.42) years) were enrolled from the Clinic of Children Behavioral Disorder in the third affiliated hospital of Sun Yat-sen University. And 28 normally reading children (mean age (10.06 +/- 1.29) years), 1:1 matched by age, sex, grade and family condition were chosen from an elementary school in Guangzhou as a control group. Four groups of pictures (cock, accident, canyon, meditate) from Picture Vocabulary Test were chosen as eye movement experiment targets. All the subjects carried out the picture searching task and their eye movement data were recorded by an Eyelink II High-Speed Eye Tracker. The duration time, average fixation duration, average saccade amplitude, fixation counts and saccade counts were compared between the two groups of children. The dyslexic children had longer total fixation duration and average fixation duration (F = 7.711, P < 0.01; F = 4.520, P < 0.05), more fixation counts and saccade counts (F = 7.498, P < 0.01; F = 11.040, P < 0.01), and a smaller average saccade amplitude (F = 29.743, P < 0.01) compared with controls. But their performance in the picture vocabulary test was the same as those of the control group. The eye movement indexes were affected by the difficulty of the pictures and words, all eye movement indexes, except saccade amplitude, had a significant difference within groups (P < 0.05). Chinese dyslexic children have abnormal eye movements in picture searching, applying slow fixations, more fixations and small and frequent saccades. Their abnormal eye movement

  2. From Covert Processes to Overt Outcomes of Refutation Text Reading: The Interplay of Science Text Structure and Working Memory Capacity through Eye Fixations

    Science.gov (United States)

    Ariasi, Nicola; Mason, Lucia

    2014-01-01

    This study extends current research on the refutation text effect by investigating it in learners with different levels of working memory capacity. The purpose is to outline the link between online processes (revealed by eye fixation indices) and off-line outcomes in these learners. In science education, unlike a standard text, a refutation text…

  3. Cyclooxygenase-2 expression in the normal human eye and its expression pattern in selected eye tumours

    DEFF Research Database (Denmark)

    Wang, Jinmei; Wu, Yazhen; Heegaard, Steffen

    2011-01-01

    Purpose: Cyclooxygenase-2 (COX-2) is an enzyme involved in neoplastic processes. The purpose of the present study is to investigate COX-2 expression in the normal human eye and the expression pattern in selected eye tumours involving COX-2 expressing cells. Methods: Immunohistochemical staining...... using antibodies against COX-2 was performed on paraffin sections of normal human eyes and selected eye tumours arising from cells expressing COX-2. Results: Cyclooxygenase-2 expression was found in various structures of the normal eye. Abundant expression was seen in the cornea, iris, ciliary body...... and retina. The COX-2 expression was less in tumours deriving from the ciliary epithelium and also in retinoblastoma. Conclusion: Cyclooxygenase-2 is constitutively expressed in normal human eyes. The expression of COX-2 is much lower in selected eye tumours involving COX-2 expressing cells....

  4. Comparison of eye imaging pattern recognition using neural network

    Science.gov (United States)

    Bukhari, W. M.; Syed A., M.; Nasir, M. N. M.; Sulaima, M. F.; Yahaya, M. S.

    2015-05-01

    The beauty of eye recognition system that it is used in automatic identifying and verifies a human weather from digital images or video source. There are various behaviors of the eye such as the color of the iris, size of pupil and shape of the eye. This study represents the analysis, design and implementation of a system for recognition of eye imaging. All the eye images that had been captured from the webcam in RGB format must through several techniques before it can be input for the pattern and recognition processes. The result shows that the final value of weight and bias after complete training 6 eye images for one subject is memorized by the neural network system and be the reference value of the weight and bias for the testing part. The target classifies to 5 different types for 5 subjects. The eye images can recognize the subject based on the target that had been set earlier during the training process. When the values between new eye image and the eye image in the database are almost equal, it is considered the eye image is matched.

  5. Capsule-Fixated Intraocular Lens Implantation in Small Pupil Cases.

    Science.gov (United States)

    Schojai, Merita; Schultz, Tim; Burkhard Dick, H

    2017-08-01

    To describe a new technique for implantation of capsule-fixated intraocular lenses (IOLs) (FEMTIS; Oculentis, Berlin, Germany) in patients with small pupils. In 4 eyes with small pupils, an anterior capsule-fixated IOL was implanted into the capsular bag after femtosecond laser treatment. The two large and two small flaps of the IOL were elevated to the front of the iris and the anterior capsule. Finally, the iris was flipped over the flaps to ensure a fixation of the capsule inside of the capsulotomy. In all cases, the implantation of anterior capsule-fixated IOLs was possible. No complications occurred during surgery or within the first months after surgery. With the described technique, capsulefixated IOLs can be implanted in eyes with small pupil easily and safely. This type of IOL has great potential to improve the refractive outcome by better prediction of the postoperative IOL position and eliminating IOL rotation after cataract surgery. [J Refract Surg. 2017;33(8):568-570.]. Copyright 2017, SLACK Incorporated.

  6. Intraocular lens iris fixation. Clinical and macular OCT outcomes

    Science.gov (United States)

    2012-01-01

    Background To assess the efficacy, clinical outcomes, visual acuity (VA), incidence of adverse effects, and complications of peripheral iris fixation of 3-piece acrylic IOLs in eyes lacking capsular support. Thirteen patients who underwent implantation and peripheral iris fixation of a 3-piece foldable acrylic PC IOL for aphakia in the absence of capsular support were followed after surgery. Clinical outcomes and macular SD-OCT (Cirrus OCT; Carl Zeiss Meditec, Germany) were analyzed. Findings The final CDVA was 20/40 or better in 8 eyes (62%), 20/60 or better in 12 eyes (92%), and one case of 20/80 due to corneal astigmatism and mild persistent edema. No intraoperative complications were reported. There were seven cases of medically controlled ocular hypertension after surgery due to the presence of viscoelastic in the AC. There were no cases of cystoid macular edema, chronic iridocyclitis, IOL subluxation, pigment dispersion, or glaucoma. Macular edema did not develop in any case by means of SD-OCT. Conclusions We think that this technique for iris suture fixation provides safe and effective results. Patients had substantial improvements in UDVA and CDVA. This surgical strategy may be individualized however; age, cornea status, angle structures, iris anatomy, and glaucoma are important considerations in selecting candidates for an appropriate IOL fixation method. PMID:23050659

  7. Pattern of Eye Problems of the Elderly in a Nigerian Tertiary Health ...

    African Journals Online (AJOL)

    The pattern of eye problems in 1,964 elderly Nigerians (972 males and 992 females) attending University of Ilorin Teaching Hospital over a 5-year period were reviewed and documented. This is aimed at determining the hospital incidence and pattern of eye problems among elderly Nigerians. retrospective case series ...

  8. Objective measurement of intraocular forward light scatter using Hartmann-Shack spot patterns from clinical aberrometers. Model-eye and human-eye study.

    Science.gov (United States)

    Cerviño, Alejandro; Bansal, Dheeraj; Hosking, Sarah L; Montés-Micó, Robert

    2008-07-01

    To apply software-based image-analysis tools to objectively determine intraocular scatter determined from clinically derived Hartmann-Shack patterns. Aston Academy of Life Sciences, Aston University, Birmingham, United Kingdom, and Department of Optics, University of Valencia, Valencia, Spain. Purpose-designed image-analysis software was used to quantify scatter from centroid patterns obtained using a clinical Hartmann-Shack analyzer (WASCA, Zeiss/Meditec). Three scatter values, as the maximum standard deviation within a lenslet for all lenslets in the pattern, were obtained in 6 model eyes and 10 human eyes. In the model-eye sample, patterns were obtained in 4 sessions: 2 without realigning between measurements, 1 with realignment, and 1 with an angular shift of 6 degrees from the instrument axis. Three measurements were made in the human eyes with the C-Quant straylight meter (Oculus) to obtain psychometric and objective measures of retinal straylight. Analysis of variance, intraclass correlation coefficients, coefficient of repeatability (CoR), and correlations were used to determine intrasession and intersession repeatability and the relationship between measures. No significant differences were found between the sessions in the model eye (P=.234). The mean CoR was less than 10% in all model- and human-eye sessions. After incomplete patterns were removed, good correlation was achieved between psychometric and objective scatter measurements despite the small sample size (n=6; r=-0.831; P=.040). The methodology was repeatable in model and human eyes, strong against realignment and misalignment, and sensitive. Clinical application would benefit from effective use of the sensor's dynamic range.

  9. Incidence and Pattern of Retinal Detachment in a Tertiary Eye ...

    African Journals Online (AJOL)

    Objectives: The aim was to determine the hospital incidence, pattern and clinical presentation of retinal detachment at the Guinness Eye Center, Onitsha, Nigeria. Materials and Methods: Case files of all retinal detachment patients seen at the Guinness Eye Center Onitsha between June 1997 and May 2012 were reviewed.

  10. Measuring vigilance decrement using computer vision assisted eye tracking in dynamic naturalistic environments.

    Science.gov (United States)

    Bodala, Indu P; Abbasi, Nida I; Yu Sun; Bezerianos, Anastasios; Al-Nashash, Hasan; Thakor, Nitish V

    2017-07-01

    Eye tracking offers a practical solution for monitoring cognitive performance in real world tasks. However, eye tracking in dynamic environments is difficult due to high spatial and temporal variation of stimuli, needing further and thorough investigation. In this paper, we study the possibility of developing a novel computer vision assisted eye tracking analysis by using fixations. Eye movement data is obtained from a long duration naturalistic driving experiment. Source invariant feature transform (SIFT) algorithm was implemented using VLFeat toolbox to identify multiple areas of interest (AOIs). A new measure called `fixation score' was defined to understand the dynamics of fixation position between the target AOI and the non target AOIs. Fixation score is maximum when the subjects focus on the target AOI and diminishes when they gaze at the non-target AOIs. Statistically significant negative correlation was found between fixation score and reaction time data (r =-0.2253 and pdecrement, the fixation score decreases due to visual attention shifting away from the target objects resulting in an increase in the reaction time.

  11. Intraocular lens iris fixation. Clinical and macular OCT outcomes

    Directory of Open Access Journals (Sweden)

    Garcia-Rojas Leonardo

    2012-10-01

    Full Text Available Abstract Background To assess the efficacy, clinical outcomes, visual acuity (VA, incidence of adverse effects, and complications of peripheral iris fixation of 3-piece acrylic IOLs in eyes lacking capsular support. Thirteen patients who underwent implantation and peripheral iris fixation of a 3-piece foldable acrylic PC IOL for aphakia in the absence of capsular support were followed after surgery. Clinical outcomes and macular SD-OCT (Cirrus OCT; Carl Zeiss Meditec, Germany were analyzed. Findings The final CDVA was 20/40 or better in 8 eyes (62%, 20/60 or better in 12 eyes (92%, and one case of 20/80 due to corneal astigmatism and mild persistent edema. No intraoperative complications were reported. There were seven cases of medically controlled ocular hypertension after surgery due to the presence of viscoelastic in the AC. There were no cases of cystoid macular edema, chronic iridocyclitis, IOL subluxation, pigment dispersion, or glaucoma. Macular edema did not develop in any case by means of SD-OCT. Conclusions We think that this technique for iris suture fixation provides safe and effective results. Patients had substantial improvements in UDVA and CDVA. This surgical strategy may be individualized however; age, cornea status, angle structures, iris anatomy, and glaucoma are important considerations in selecting candidates for an appropriate IOL fixation method.

  12. Eye tracking to explore attendance in health-state descriptions.

    Directory of Open Access Journals (Sweden)

    Anna Selivanova

    Full Text Available A crucial assumption in health valuation methods is that respondents pay equal attention to all information components presented in the response task. So far, there is no solid evidence that respondents are fulfilling this condition. The aim of our study is to explore the attendance to various information cues presented in the discrete choice (DC response tasks.Eye tracking was used to study the eye movements and fixations on specific information areas. This was done for seven DC response tasks comprising health-state descriptions. A sample of 10 respondents participated in the study. Videos of their eye movements were recorded and are presented graphically. Frequencies were computed for length of fixation and number of fixations, so differences in attendance were demonstrated for particular attributes in the tasks.All respondents completed the survey. Respondents were fixating on the left-sided health-state descriptions slightly longer than on the right-sided. Fatigue was not observed, as the time spent did not decrease in the final response tasks. The time spent on the tasks depended on the difficulty of the task and the amount of information presented.Eye tracking proved to be a feasible method to study the process of paying attention and fixating on health-state descriptions in the DC response tasks. Eye tracking facilitates the investigation of whether respondents fully read the information in health descriptions or whether they ignore particular elements.

  13. Eye size at birth in prosimian primates: life history correlates and growth patterns.

    Directory of Open Access Journals (Sweden)

    Joshua R Cummings

    Full Text Available BACKGROUND: Primates have large eyes relative to head size, which profoundly influence the ontogenetic emergence of facial form. However, growth of the primate eye is only understood in a narrow taxonomic perspective, with information biased toward anthropoids. METHODOLOGY/PRINCIPAL FINDINGS: We measured eye and bony orbit size in perinatal prosimian primates (17 strepsirrhine taxa and Tarsius syrichta to infer the extent of prenatal as compared to postnatal eye growth. In addition, multiple linear regression was used to detect relationships of relative eye and orbit diameter to life history variables. ANOVA was used to determine if eye size differed according to activity pattern. In most of the species, eye diameter at birth measures more than half of that for adults. Two exceptions include Nycticebus and Tarsius, in which more than half of eye diameter growth occurs postnatally. Ratios of neonate/adult eye and orbit diameters indicate prenatal growth of the eye is actually more rapid than that of the orbit. For example, mean neonatal transverse eye diameter is 57.5% of the adult value (excluding Nycticebus and Tarsius, compared to 50.8% for orbital diameter. If Nycticebus is excluded, relative gestation age has a significant positive correlation with relative eye diameter in strepsirrhines, explaining 59% of the variance in relative transverse eye diameter. No significant differences were found among species with different activity patterns. CONCLUSIONS/SIGNIFICANCE: The primate developmental strategy of relatively long gestations is probably tied to an extended period of neural development, and this principle appears to apply to eye growth as well. Our findings indicate that growth rates of the eye and bony orbit are disassociated, with eyes growing faster prenatally, and the growth rate of the bony orbit exceeding that of the eyes after birth. Some well-documented patterns of orbital morphology in adult primates, such as the enlarged orbits

  14. Differences in Sequential Eye Movement Behavior between Taiwanese and American Viewers

    Directory of Open Access Journals (Sweden)

    Yen Ju eLee

    2016-05-01

    Full Text Available Knowledge of how information is sought in the visual world is useful for predicting and simulating human behavior. Taiwanese participants and American participants were instructed to judge the facial expression of a focal face that was flanked horizontally by other faces while their eye movements were monitored. The Taiwanese participants distributed their eye fixations more widely than American participants, started to look away from the focal face earlier than American participants, and spent a higher percentage of time looking at the flanking faces. Eye movement transition matrices also provided evidence that Taiwanese participants continually, and systematically shifted gaze between focal and flanking faces. Eye movement patterns were less systematic and less prevalent in American participants. This suggests that both cultures utilized different attention allocation strategies. The results highlight the importance of determining sequential eye movement statistics in cross-cultural research on the utilization of visual context.

  15. Eye fixations indicate men's preference for female breasts or buttocks.

    Science.gov (United States)

    Dagnino, Bruno; Navajas, Joaquin; Sigman, Mariano

    2012-08-01

    Evolutionary psychologists have been interested in male preferences for particular female traits that are thought to signal health and reproductive potential. While the majority of studies have focused on what makes specific body traits attractive-such as the waist-to-hip ratio, the body mass index, and breasts shape and size-there is little empirical research that has examined individual differences in male preferences for specific traits (e.g., favoring breasts over buttocks). The current study begins to fill this empirical gap. In the first experiment (Study 1), 184 male participants were asked to report their preference between breasts and buttocks on a continuous scale. We found that (1) the distribution of preference was bimodal, indicating that Argentinean males tended to define themselves as favoring breasts or buttocks but rarely thinking that these traits contributed equally to their choice and (2) the distribution was biased towards buttocks. In a second experiment (Study 2), 19 male participants were asked to rate pictures of female breasts and buttocks. This study was necessary to generate three categories of pictures with statistically different ratings (high, medium, and low). In a third experiment (Study 3), we recorded eye-movements of 25 male participants while they chose the more attractive between two women, only seeing their breasts and buttock. We found that the first and last fixations were systematically directed towards the self-reported preferred trait.

  16. Exploratory eye movements to pictures in childhood-onset schizophrenia and attention-deficit/hyperactivity disorder (ADHD).

    Science.gov (United States)

    Karatekin, C; Asarnow, R F

    1999-02-01

    We investigated exploratory eye movements to thematic pictures in schizophrenic, attention-deficit/hyperactivity disorder (ADHD), and normal children. For each picture, children were asked three questions varying in amount of structure. We tested if schizophrenic children would stare or scan extensively and if their scan patterns were differentially affected by the question. Time spent viewing relevant and irrelevant regions, fixation duration (an estimate of processing rate), and distance between fixations (an estimate of breadth of attention) were measured. ADHD children showed a trend toward shorter fixations than normals on the question requiring the most detailed analysis. Schizophrenic children looked at fewer relevant, but not more irrelevant, regions than normals. They showed a tendency to stare more when asked to decide what was happening but not when asked to attend to specific regions. Thus, lower levels of visual attention (e.g., basic control of eye movements) were intact in schizophrenic children. In contrast, they had difficulty with top-down control of selective attention in the service of self-guided behavior.

  17. Methods of fixation of intraocular lenses according to the anatomical structures in trauma eyes.

    Science.gov (United States)

    Fiorentzis, Miltiadis; Viestenz, Anja; Heichel, Jens; Seitz, Berthold; Hammer, Thomas; Viestenz, Arne

    2018-01-01

    Ocular trauma can lead to severe visual impairment and morbidity, depending on the anatomical structures affected. The main causes of ocular trauma include foreign bodies, impact by an object, falls, and chemicals. Most ocular traumas occur in children or young male adults. A meticulous slit lamp examination is crucial for assessing all anatomical structures. Trauma to the crystalline lens can result in dislocation, an intralenticular foreign body, cataract, fragmentation, and capsular breach. An intraocular lens (IOL) can endure subluxation or luxation under the conjunctiva, into the anterior chamber or the vitreous, or can be extruded. The surgical approach depends on the condition and morphology of the lens and the anatomical structures surrounding it. If there is capsular bag support, a secondary IOL can be placed in the sulcus using remnants of the damaged capsule. If there is no capsular bag support, a secondary IOL can be fixated to the anterior chamber angle, to the iris, or to the sclera. A detailed history of injury cannot always be obtained in trauma settings. Proper education, supervision, and certified safety eye protectors could prevent up to 90% of ocular injuries. Lens trauma can be treated with various surgical procedures and fixation techniques, which nevertheless require advanced surgical skills owing to the fine anatomical structure of the anterior segment. A careful surgical strategy should be established for a globe reconstruction after trauma with secondary lens implantation. Clin. Anat. 31:6-15, 2018. © 2017 Wiley Periodicals, Inc. © 2017 Wiley Periodicals, Inc.

  18. Patterning of a compound eye on an extinct dipteran wing

    OpenAIRE

    Dinwiddie, April; Rachootin, Stan

    2010-01-01

    We have discovered unexpected similarities between a novel and characteristic wing organ in an extinct biting midge from Baltic amber, Eohelea petrunkevitchi, and the surface of a dipteran's compound eye. Scanning electron microscope images now reveal vestigial mechanoreceptors between the facets of the organ. We interpret Eohelea's wing organ as the blending of these two developmental systems: the formation and patterning of the cuticle in the eye and of the wing.

  19. Where do neurologists look when viewing brain CT images? An eye-tracking study involving stroke cases.

    Directory of Open Access Journals (Sweden)

    Hideyuki Matsumoto

    Full Text Available The aim of this study was to investigate where neurologists look when they view brain computed tomography (CT images and to evaluate how they deploy their visual attention by comparing their gaze distribution with saliency maps. Brain CT images showing cerebrovascular accidents were presented to 12 neurologists and 12 control subjects. The subjects' ocular fixation positions were recorded using an eye-tracking device (Eyelink 1000. Heat maps were created based on the eye-fixation patterns of each group and compared between the two groups. The heat maps revealed that the areas on which control subjects frequently fixated often coincided with areas identified as outstanding in saliency maps, while the areas on which neurologists frequently fixated often did not. Dwell time in regions of interest (ROI was likewise compared between the two groups, revealing that, although dwell time on large lesions was not different between the two groups, dwell time in clinically important areas with low salience was longer in neurologists than in controls. Therefore it appears that neurologists intentionally scan clinically important areas when reading brain CT images showing cerebrovascular accidents. Both neurologists and control subjects used the "bottom-up salience" form of visual attention, although the neurologists more effectively used the "top-down instruction" form.

  20. Observing eye movements and the influence of cognition during a symbol search task: a comparison across three age groups.

    Science.gov (United States)

    Perrin, Maxine; Robillard, Manon; Roy-Charland, Annie

    2017-12-01

    This study examined eye movements during a visual search task as well as cognitive abilities within three age groups. The aim was to explore scanning patterns across symbol grids and to better understand the impact of symbol location in AAC displays on speed and accuracy of symbol selection. For the study, 60 students were asked to locate a series of symbols on 16 cell grids. The EyeLink 1000 was used to measure eye movements, accuracy, and response time. Accuracy was high across all cells. Participants had faster response times, longer fixations, and more frequent fixations on symbols located in the middle of the grid. Group comparisons revealed significant differences for accuracy and reaction times. The Leiter-R was used to evaluate cognitive abilities. Sustained attention and cognitive flexibility scores predicted the participants' reaction time and accuracy in symbol selection. Findings suggest that symbol location within AAC devices and individuals' cognitive abilities influence the speed and accuracy of retrieving symbols.

  1. Comparative study of fixation density maps

    NARCIS (Netherlands)

    Engelke, U.; Liu, H.; Wang, Junle; Callet, Le P.; Heynderickx, I.E.J.; Zepernick, H.-J.; Maeder, A.

    2013-01-01

    Fixation density maps (FDM) created from eye tracking experiments are widely used in image processing applications. The FDM are assumed to be reliable ground truths of human visual attention and as such, one expects a high similarity between FDM created in different laboratories. So far, no studies

  2. A two-step patterning process increases the robustness of periodic patterning in the fly eye.

    Science.gov (United States)

    Gavish, Avishai; Barkai, Naama

    2016-06-01

    Complex periodic patterns can self-organize through dynamic interactions between diffusible activators and inhibitors. In the biological context, self-organized patterning is challenged by spatial heterogeneities ('noise') inherent to biological systems. How spatial variability impacts the periodic patterning mechanism and how it can be buffered to ensure precise patterning is not well understood. We examine the effect of spatial heterogeneity on the periodic patterning of the fruit fly eye, an organ composed of ∼800 miniature eye units (ommatidia) whose periodic arrangement along a hexagonal lattice self-organizes during early stages of fly development. The patterning follows a two-step process, with an initial formation of evenly spaced clusters of ∼10 cells followed by a subsequent refinement of each cluster into a single selected cell. Using a probabilistic approach, we calculate the rate of patterning errors resulting from spatial heterogeneities in cell size, position and biosynthetic capacity. Notably, error rates were largely independent of the desired cluster size but followed the distributions of signaling speeds. Pre-formation of large clusters therefore greatly increases the reproducibility of the overall periodic arrangement, suggesting that the two-stage patterning process functions to guard the pattern against errors caused by spatial heterogeneities. Our results emphasize the constraints imposed on self-organized patterning mechanisms by the need to buffer stochastic effects. Author summary Complex periodic patterns are common in nature and are observed in physical, chemical and biological systems. Understanding how these patterns are generated in a precise manner is a key challenge. Biological patterns are especially intriguing, as they are generated in a noisy environment; cell position and cell size, for example, are subject to stochastic variations, as are the strengths of the chemical signals mediating cell-to-cell communication. The need

  3. Fixation and its role in the causation, laterality and location of pterygium: a study in amblyopes and non-amblyopes.

    Science.gov (United States)

    Sudhalkar, A

    2012-03-01

    To evaluate the role of fixation in causing pterygium and determining its laterality and location. This is a prospective, observational, case-control study. Cases were defined as patients with primary pterygium who had unilateral amblyopia with eccentric fixation. Controls were age-matched patients with primary pterygium, but without amblyopia and eccentric fixation. All patients underwent complete ocular, orthoptic, and systemic examination and a detailed risk-factor assessment (latitude of residence, exposure to sunlight, sand, and a high-reflectance environment). The role of fixation in the causation, laterality and location of pterygium was evaluated. Fisher's exact test, the unpaired t-test, and odds ratio (OR) were carried out to determine the significance of the observations. The mean age of subjects was 47.1±5.25 years in cases (n=107) and 48.2±4.75 years in controls (n=310; P=0.78). As far as known risk factors were concerned, both groups were evenly matched. Among the cases, 88 (82.2%) patients demonstrated suppression of the amblyopic eye and 19 (17.8%) patients had abnormal retinal correspondence (ARC). Patients with suppression had a unilateral pterygium in the better (fixating) eye, whereas those with ARC had bilateral pterygia. Among the controls, 192 (61.9%) eyes had bilateral pterygia and 118 (38.1%) eyes had unilateral pterygium. In controls, the dominant eye had a higher prevalence of pterygium. All patients in both groups had a nasal pterygium. Pterygium and fixation were strongly associated (P=0.007; Fisher's exact test; OR -15.98; P=0.008). Fixation appears to have an important role in causing pterygium and determining its location and laterality.

  4. Bilateral spontaneous subluxation of scleral-fixated intraocular lenses.

    Science.gov (United States)

    Assia, Ehud I; Nemet, Arie; Sachs, Dani

    2002-12-01

    Two young men with primary ectopic lenses had intracapsular cataract extraction and scleral fixation of posterior chamber intraocular lenses (PC IOLs) using 10-0 polypropylene sutures tied to the IOL eyelets. Three to 9 years after implantation, spontaneous IOL vertical subluxation occurred in all 4 eyes (5 IOL loops), probably because of suture breakage. Late subluxation of a sutured IOL may occur several years after implantation. Double fixation and thicker sutures should be considered, especially in young patients.

  5. Fixation and saliency during search of natural scenes: the case of visual agnosia.

    Science.gov (United States)

    Foulsham, Tom; Barton, Jason J S; Kingstone, Alan; Dewhurst, Richard; Underwood, Geoffrey

    2009-07-01

    Models of eye movement control in natural scenes often distinguish between stimulus-driven processes (which guide the eyes to visually salient regions) and those based on task and object knowledge (which depend on expectations or identification of objects and scene gist). In the present investigation, the eye movements of a patient with visual agnosia were recorded while she searched for objects within photographs of natural scenes and compared to those made by students and age-matched controls. Agnosia is assumed to disrupt the top-down knowledge available in this task, and so may increase the reliance on bottom-up cues. The patient's deficit in object recognition was seen in poor search performance and inefficient scanning. The low-level saliency of target objects had an effect on responses in visual agnosia, and the most salient region in the scene was more likely to be fixated by the patient than by controls. An analysis of model-predicted saliency at fixation locations indicated a closer match between fixations and low-level saliency in agnosia than in controls. These findings are discussed in relation to saliency-map models and the balance between high and low-level factors in eye guidance.

  6. Neurons in the monkey amygdala detect eye-contact during naturalistic social interactions

    Science.gov (United States)

    Mosher, Clayton P.; Zimmerman, Prisca E.; Gothard, Katalin M.

    2014-01-01

    Summary Primates explore the visual world through eye-movement sequences. Saccades bring details of interest into the fovea while fixations stabilize the image [1]. During natural vision, social primates direct their gaze at the eyes of others to communicate their own emotions and intentions and to gather information about the mental states of others [2]. Direct gaze is an integral part of facial expressions that signals cooperation or conflict over resources and social status [3-6]. Despite the great importance of making and breaking eye contact in the behavioral repertoire of primates, little is known about the neural substrates that support these behaviors. Here we show that the monkey amygdala contains neurons that respond selectively to fixations at the eyes of others and to eye contact. These “eye cells” share several features with the canonical, visually responsive neurons in the monkey amygdala, however, they respond to the eyes only when they fall within the fovea of the viewer, either as a result of a deliberate saccade, or as eyes move into the fovea of the viewer during a fixation intended to explore a different feature. The presence of eyes in peripheral vision fails to activate the eye cells. These findings link the primate amygdala to eye-movements involved in the exploration and selection of details in visual scenes that contain socially and emotionally salient features. PMID:25283782

  7. Neurons in the monkey amygdala detect eye contact during naturalistic social interactions.

    Science.gov (United States)

    Mosher, Clayton P; Zimmerman, Prisca E; Gothard, Katalin M

    2014-10-20

    Primates explore the visual world through eye-movement sequences. Saccades bring details of interest into the fovea, while fixations stabilize the image. During natural vision, social primates direct their gaze at the eyes of others to communicate their own emotions and intentions and to gather information about the mental states of others. Direct gaze is an integral part of facial expressions that signals cooperation or conflict over resources and social status. Despite the great importance of making and breaking eye contact in the behavioral repertoire of primates, little is known about the neural substrates that support these behaviors. Here we show that the monkey amygdala contains neurons that respond selectively to fixations on the eyes of others and to eye contact. These "eye cells" share several features with the canonical, visually responsive neurons in the monkey amygdala; however, they respond to the eyes only when they fall within the fovea of the viewer, either as a result of a deliberate saccade or as eyes move into the fovea of the viewer during a fixation intended to explore a different feature. The presence of eyes in peripheral vision fails to activate the eye cells. These findings link the primate amygdala to eye movements involved in the exploration and selection of details in visual scenes that contain socially and emotionally salient features. Copyright © 2014 Elsevier Ltd. All rights reserved.

  8. Retinal image registration for eye movement estimation.

    Science.gov (United States)

    Kolar, Radim; Tornow, Ralf P; Odstrcilik, Jan

    2015-01-01

    This paper describes a novel methodology for eye fixation measurement using a unique videoophthalmoscope setup and advanced image registration approach. The representation of the eye movements via Poincare plot is also introduced. The properties, limitations and perspective of this methodology are finally discussed.

  9. Long-term follow-up after scleral lens fixation in patients with Marfan syndrome.

    Science.gov (United States)

    Luebke, Jan; Reinhard, Thomas; Agostini, Hansjuergen; Boehringer, Daniel; Eberwein, Philipp

    2017-12-06

    The dislocation of the crystalline lens is a common finding in patients with Marfan syndrome (MFS). Scleral intraocular lens (IOL) fixation is an accepted treatment method of this complication. To now, no long-term data on scleral IOL fixation in MFS exist. We present a retrospective study of 27 eyes of 17 MFS patients that underwent scleral lens fixation at our clinic between 1999 and 2012. These patients are compared to an age- and surgeon-matched group of 31 eyes of 27 patients who underwent the same procedure for reasons other than MFS. The median age in the MFS group was 35.4 years versus 35.6 years in the non-MFS group. The median follow-up was 4 years for MFS and 3 years for non-MFS. In the MFS group, significantly more IOL-dislocations occurred than compared to the non-MFS group (30% vs. 6.5%, p = 0.02). Retinal detachment occurred in four MFS-eyes compared to three eyes in the non-MFS group. Biometry prediction error was 1.11 diopters (D) for MFS and 1.33 D for non-MFS (p = 0.11). Median BCVA (best-corrected visual acuity, logMAR) was 0.1 in the MFS group versus 0.3 in non-MFS patients. Scleral lens fixation in MFS patients achieves satisfying visual and refractive outcomes. Our data shows a significantly higher rate of IOL dislocations in patients with MFS. We therefore recommend addressing this complication preoperatively.

  10. Finite element analysis of three patterns of internal fixation of fractures of the mandibular condyle.

    Science.gov (United States)

    Aquilina, Peter; Chamoli, Uphar; Parr, William C H; Clausen, Philip D; Wroe, Stephen

    2013-06-01

    The most stable pattern of internal fixation for fractures of the mandibular condyle is a matter for ongoing discussion. In this study we investigated the stability of three commonly used patterns of plate fixation, and constructed finite element models of a simulated mandibular condylar fracture. The completed models were heterogeneous in the distribution of bony material properties, contained about 1.2 million elements, and incorporated simulated jaw-adducting musculature. Models were run assuming linear elasticity and isotropic material properties for bone. This model was considerably larger and more complex than previous finite element models that have been used to analyse the biomechanical behaviour of differing plating techniques. The use of two parallel 2.0 titanium miniplates gave a more stable configuration with lower mean element stresses and displacements over the use of a single miniplate. In addition, a parallel orientation of two miniplates resulted in lower stresses and displacements than did the use of two miniplates in an offset pattern. The use of two parallel titanium plates resulted in a superior biomechanical result as defined by mean element stresses and relative movement between the fractured fragments in these finite element models. Copyright © 2012 The British Association of Oral and Maxillofacial Surgeons. Published by Elsevier Ltd. All rights reserved.

  11. Visual and linguistic determinants of the eyes' initial fixation position in reading development.

    Science.gov (United States)

    Ducrot, Stéphanie; Pynte, Joël; Ghio, Alain; Lété, Bernard

    2013-03-01

    Two eye-movement experiments with one hundred and seven first- through fifth-grade children were conducted to examine the effects of visuomotor and linguistic factors on the recognition of words and pseudowords presented in central vision (using a variable-viewing-position technique) and in parafoveal vision (shifted to the left or right of a central fixation point). For all groups of children, we found a strong effect of stimulus location, in both central and parafoveal vision. This effect corresponds to the children's apparent tendency, for peripherally located targets, to reach a position located halfway between the middle and the left edge of the stimulus (preferred viewing location, PVL), whether saccading to the right or left. For centrally presented targets, refixation probability and lexical-decision time were the lowest near the word's center, suggesting an optimal viewing position (OVP). The viewing-position effects found here were modulated (1) by print exposure, both in central and parafoveal vision; and (2) by the intrinsic qualities of the stimulus (lexicality and word frequency) for targets in central vision but not for parafoveally presented targets. Copyright © 2013 Elsevier B.V. All rights reserved.

  12. Ocular injuries and eye care seeking patterns following injuries ...

    African Journals Online (AJOL)

    Background: The work environment of cocoa farmers exposes them to several ocular hazards that predispose them to eye diseases and injuries. However, the extent of ocular injuries and health seeking patterns following these injuries are unknown among cocoa farmers in Ghana. Objectives: To determine the prevalence ...

  13. Functional magnetic resonance imaging of the frontal eye fields during saccadic eye movements

    International Nuclear Information System (INIS)

    Miki, Atsushi; Takagi, Mineo; Abe, Haruki; Nakajima, Takashi; Miyauchi, Satoru.

    1996-01-01

    We evaluated activity-induced signal intensity changes in the human cerebral cortex during horizontal saccadic eye movements using functional magnetic resonance imaging (fMRI) based on the blood-oxygenation-level-dependent (BOLD) contrast method. Compared with central fixation, significant signal increases were observed bilaterally in the middle frontal gyrus (Brodmann area 8) during saccadic conditions. The location of the activated area was consistent with that of previously reported frontal eye fields (FEF). These results suggest that fMRI has potential merit for the study of cortical control of eye movements in humans. (author)

  14. Pattern of Eye Diseases among Commercial Intercity Vehicle Drivers ...

    African Journals Online (AJOL)

    Objective: To determine the pattern of eye diseases among commercial intercity vehicle drivers (CIVDs) in Ilorin, Nigeria. Design: A cross-sectional descriptive study. Methodology: Out of the estimated 450 drivers operating in the five major motor parks for CIVDs in Ilorin, 399 consecutive drivers participated in the study.

  15. SR and LR Union Suture for the Treatment of Myopic Strabismus Fixus: Is Scleral Fixation Necessary?

    Directory of Open Access Journals (Sweden)

    Carol P. S. Lam

    2015-01-01

    Full Text Available Purpose. To evaluate and compare the effectiveness of scleral fixation SR and LR union suture and nonscleral fixation union suture for the treatment of myopic strabismus fixus. Methods. Retrospective review of 32 eyes of 22 patients with myopic strabismus fixus who had undergone union suture of superior rectus (SR and lateral rectus (LR with or without scleral fixation, and follow-up longer than 6 months at Hong Kong Eye Hospital from 2006 to 2013. Surgical techniques and outcomes in terms of ocular alignment are analyzed. Results. There is significant overall improvement both in postoperative angle of esodeviation (P0.05. Conclusions. Union suture of SR and LR is an effective procedure in correcting myopic strabismus fixus. Fixation of the union suture to the sclera does not improve surgical outcome.

  16. The role of eye movement driven attention in functional strabismic amblyopia.

    Science.gov (United States)

    Wang, Hao; Crewther, Sheila Gillard; Yin, Zheng Qin

    2015-01-01

    Strabismic amblyopia "blunt vision" is a developmental anomaly that affects binocular vision and results in lowered visual acuity. Strabismus is a term for a misalignment of the visual axes and is usually characterized by impaired ability of the strabismic eye to take up fixation. Such impaired fixation is usually a function of the temporally and spatially impaired binocular eye movements that normally underlie binocular shifts in visual attention. In this review, we discuss how abnormal eye movement function in children with misaligned eyes influences the development of normal binocular visual attention and results in deficits in visual function such as depth perception. We also discuss how eye movement function deficits in adult amblyopia patients can also lead to other abnormalities in visual perception. Finally, we examine how the nonamblyopic eye of an amblyope is also affected in strabismic amblyopia.

  17. The Role of Eye Movement Driven Attention in Functional Strabismic Amblyopia

    Directory of Open Access Journals (Sweden)

    Hao Wang

    2015-01-01

    Full Text Available Strabismic amblyopia “blunt vision” is a developmental anomaly that affects binocular vision and results in lowered visual acuity. Strabismus is a term for a misalignment of the visual axes and is usually characterized by impaired ability of the strabismic eye to take up fixation. Such impaired fixation is usually a function of the temporally and spatially impaired binocular eye movements that normally underlie binocular shifts in visual attention. In this review, we discuss how abnormal eye movement function in children with misaligned eyes influences the development of normal binocular visual attention and results in deficits in visual function such as depth perception. We also discuss how eye movement function deficits in adult amblyopia patients can also lead to other abnormalities in visual perception. Finally, we examine how the nonamblyopic eye of an amblyope is also affected in strabismic amblyopia.

  18. Late dislocation of in-the-bag intraocular lenses in uveitic eyes: An analysis of management and complications

    Directory of Open Access Journals (Sweden)

    Sudha K Ganesh

    2017-01-01

    Full Text Available Aim: An analysis of late in-the-bag dislocation of intraocular lenses (IOL, in uveitic eyes. Setting: Referral uveitis clinic. Design: Retrospective case series. Materials and Methods: All case records of eyes with chronic uveitis that had phacoemulsification with IOL implantation, at a referral uveitis clinic between February 1997 and January 2015 were retrieved and analyzed. Only those eyes with no documented intraoperative complication and no predisposing risks to IOL dislocation, such as pseudoexfoliation, high myopia, trauma, and prior VR surgery were included in this study. Results: A total of 581 eyes with chronic uveitis underwent phacoemulsification with IOL implantation under steroid cover from February 1997 to December 2015. Out of these 581 eyes, 10 patients (11 eyes had experienced late in-the-bag IOL dislocation (1.89%. All 11 eyes had chronic intermediate uveitis. The mean duration from the time of cataract surgery to IOL dislocation was 11.24 years. 5 out of 11 eyes had pars plana vitrectomy (PPV with IOL removal with 4-point sutured scleral fixated IOL. Two out of 11 eyes had PPV with in-the-bag IOL re-fixation. Out of 11, 2 eyes had PPV with IOL removal only. Remaining 2 eyes of 2 patients did not opt for surgery. Out of 11, 8 eyes had improved vision at last follow-up. Conclusions: In-the-bag dislocation of IOL is a rare late complication in uveitic eyes. With tight perioperative inflammatory control, scleral-fixated posterior chamber intraocular lens or IOL re-fixation are good options of restoring vision in these high-risk eyes.

  19. Online webcam-based eye tracking in cognitive science: A first look.

    Science.gov (United States)

    Semmelmann, Kilian; Weigelt, Sarah

    2018-04-01

    Online experimentation is emerging in many areas of cognitive psychology as a viable alternative or supplement to classical in-lab experimentation. While performance- and reaction-time-based paradigms are covered in recent studies, one instrument of cognitive psychology has not received much attention up to now: eye tracking. In this study, we used JavaScript-based eye tracking algorithms recently made available by Papoutsaki et al. (International Joint Conference on Artificial Intelligence, 2016) together with consumer-grade webcams to investigate the potential of online eye tracking to benefit from the common advantages of online data conduction. We compared three in-lab conducted tasks (fixation, pursuit, and free viewing) with online-acquired data to analyze the spatial precision in the first two, and replicability of well-known gazing patterns in the third task. Our results indicate that in-lab data exhibit an offset of about 172 px (15% of screen size, 3.94° visual angle) in the fixation task, while online data is slightly less accurate (18% of screen size, 207 px), and shows higher variance. The same results were found for the pursuit task with a constant offset during the stimulus movement (211 px in-lab, 216 px online). In the free-viewing task, we were able to replicate the high attention attribution to eyes (28.25%) compared to other key regions like the nose (9.71%) and mouth (4.00%). Overall, we found web technology-based eye tracking to be suitable for all three tasks and are confident that the required hard- and software will be improved continuously for even more sophisticated experimental paradigms in all of cognitive psychology.

  20. Eye movement analysis for activity recognition using electrooculography.

    Science.gov (United States)

    Bulling, Andreas; Ward, Jamie A; Gellersen, Hans; Tröster, Gerhard

    2011-04-01

    In this work, we investigate eye movement analysis as a new sensing modality for activity recognition. Eye movement data were recorded using an electrooculography (EOG) system. We first describe and evaluate algorithms for detecting three eye movement characteristics from EOG signals-saccades, fixations, and blinks-and propose a method for assessing repetitive patterns of eye movements. We then devise 90 different features based on these characteristics and select a subset of them using minimum redundancy maximum relevance (mRMR) feature selection. We validate the method using an eight participant study in an office environment using an example set of five activity classes: copying a text, reading a printed paper, taking handwritten notes, watching a video, and browsing the Web. We also include periods with no specific activity (the NULL class). Using a support vector machine (SVM) classifier and person-independent (leave-one-person-out) training, we obtain an average precision of 76.1 percent and recall of 70.5 percent over all classes and participants. The work demonstrates the promise of eye-based activity recognition (EAR) and opens up discussion on the wider applicability of EAR to other activities that are difficult, or even impossible, to detect using common sensing modalities.

  1. Perceptual switching, eye movements, and the bus paradox

    NARCIS (Netherlands)

    Ito, J.; Nikolaev, A.R.; Luman, M.; Aukes, M.F.; Nakatani, C.; Leeuwen, C.

    2003-01-01

    According to a widely cited finding by Ellis and Stark (1978 Perception 7 575-581), the duration of eye fixations is longer at the instant of perceptual reversal of an ambiguous figure than before or after the reversal. However, long fixations are more likely to include samples of an independent

  2. Processing rhythmic pattern during Chinese sentence reading: An eye movement study

    Directory of Open Access Journals (Sweden)

    Yingyi eLuo

    2015-12-01

    Full Text Available Prosodic constraints play a fundamental role during both spoken sentence comprehension and silent reading. In Chinese, the rhythmic pattern of the verb-object (V-O combination has been found to rapidly affect the semantic access/integration process during sentence reading (Luo and Zhou, 2010. Rhythmic pattern refers to the combination of words with different syllabic lengths, with certain combinations disallowed (e.g., [2+1]; numbers standing for the number of syllables of the verb and the noun respectively and certain combinations preferred (e.g., [1+1] or [2+2]. This constraint extends to the situation in which the combination is used to modify other words. A V-O phrase could modify a noun by simply preceding it, forming a V-O-N compound; when the verb is disyllabic, however, the word order has to be O-V-N and the object is preferred to be disyllabic. In this study, we investigated how the reader processes the rhythmic pattern and word order information by recording the reader’s eye-movements. We created four types of sentences by crossing rhythmic pattern and word order in compounding. The compound, embedding a disyllabic verb, could be in the correct O-V-N or the incorrect V-O-N order; the object could be disyllabic or monosyllabic. We found that the reader spent more time and made more regressions on and after the compounds when either type of anomaly was detected during the first pass reading. However, during re-reading (after all the words in the sentence have been viewed, less regressive eye movements were found for the anomalous rhythmic pattern, relative to the correct pattern; moreover, only the abnormal rhythmic pattern, not the violated word order, influenced the regressive eye movements. These results suggest that while the processing of rhythmic pattern and word order information occurs rapidly during the initial reading of the sentence, the process of recovering from the rhythmic pattern anomaly may ease the reanalysis

  3. Processing Rhythmic Pattern during Chinese Sentence Reading: An Eye Movement Study.

    Science.gov (United States)

    Luo, Yingyi; Duan, Yunyan; Zhou, Xiaolin

    2015-01-01

    Prosodic constraints play a fundamental role during both spoken sentence comprehension and silent reading. In Chinese, the rhythmic pattern of the verb-object (V-O) combination has been found to rapidly affect the semantic access/integration process during sentence reading (Luo and Zhou, 2010). Rhythmic pattern refers to the combination of words with different syllabic lengths, with certain combinations disallowed (e.g., [2 + 1]; numbers standing for the number of syllables of the verb and the noun respectively) and certain combinations preferred (e.g., [1 + 1] or [2 + 2]). This constraint extends to the situation in which the combination is used to modify other words. A V-O phrase could modify a noun by simply preceding it, forming a V-O-N compound; when the verb is disyllabic, however, the word order has to be O-V-N and the object is preferred to be disyllabic. In this study, we investigated how the reader processes the rhythmic pattern and word order information by recording the reader's eye-movements. We created four types of sentences by crossing rhythmic pattern and word order in compounding. The compound, embedding a disyllabic verb, could be in the correct O-V-N or the incorrect V-O-N order; the object could be disyllabic or monosyllabic. We found that the reader spent more time and made more regressions on and after the compounds when either type of anomaly was detected during the first pass reading. However, during re-reading (after all the words in the sentence have been viewed), less regressive eye movements were found for the anomalous rhythmic pattern, relative to the correct pattern; moreover, only the abnormal rhythmic pattern, not the violated word order, influenced the regressive eye movements. These results suggest that while the processing of rhythmic pattern and word order information occurs rapidly during the initial reading of the sentence, the process of recovering from the rhythmic pattern anomaly may ease the reanalysis processing at the

  4. The subject-fixated coaxially sighted corneal light reflex: a clinical marker for centration of refractive treatments and devices.

    Science.gov (United States)

    Chang, Daniel H; Waring, George O

    2014-11-01

    To describe the inconsistencies in definition, application, and usage of the ocular reference axes (optical axis, visual axis, line of sight, pupillary axis, and topographic axis) and angles (angle kappa, lambda, and alpha) and to propose a precise, reproducible, clinically defined reference marker and axis for centration of refractive treatments and devices. Perspective. Literature review of papers dealing with ocular reference axes, angles, and centration. The inconsistent definitions and usage of the current ocular axes, as derived from eye models, limit their clinical utility. With a clear understanding of Purkinje images and a defined alignment of the observer, light source/fixation target, and subject eye, the subject-fixated coaxially sighted corneal light reflex can be a clinically useful reference marker. The axis formed by connecting the subject-fixated coaxially sighted corneal light reflex and the fixation point, the subject-fixated coaxially sighted corneal light reflex axis, is independent of pupillary dilation and phakic status of the eye. The relationship of the subject-fixated coaxially sighted corneal light reflex axis to a refined definition of the visual axis without reference to nodal points, the foveal-fixation axis, is discussed. The displacement between the subject-fixated coaxially sighted corneal light reflex and pupil center is described not by an angle, but by a chord, here termed chord mu. The application of the subject-fixated coaxially sighted corneal light reflex to the surgical centration of refractive treatments and devices is discussed. As a clinically defined reference marker, the subject-fixated coaxially sighted corneal light reflex avoids the shortcomings of current ocular axes for clinical application and may contribute to better consensus in the literature and improved patient outcomes. Copyright © 2014 Elsevier Inc. All rights reserved.

  5. Is having similar eye movement patterns during face learning and recognition beneficial for recognition performance? Evidence from hidden Markov modeling.

    Science.gov (United States)

    Chuk, Tim; Chan, Antoni B; Hsiao, Janet H

    2017-12-01

    The hidden Markov model (HMM)-based approach for eye movement analysis is able to reflect individual differences in both spatial and temporal aspects of eye movements. Here we used this approach to understand the relationship between eye movements during face learning and recognition, and its association with recognition performance. We discovered holistic (i.e., mainly looking at the face center) and analytic (i.e., specifically looking at the two eyes in addition to the face center) patterns during both learning and recognition. Although for both learning and recognition, participants who adopted analytic patterns had better recognition performance than those with holistic patterns, a significant positive correlation between the likelihood of participants' patterns being classified as analytic and their recognition performance was only observed during recognition. Significantly more participants adopted holistic patterns during learning than recognition. Interestingly, about 40% of the participants used different patterns between learning and recognition, and among them 90% switched their patterns from holistic at learning to analytic at recognition. In contrast to the scan path theory, which posits that eye movements during learning have to be recapitulated during recognition for the recognition to be successful, participants who used the same or different patterns during learning and recognition did not differ in recognition performance. The similarity between their learning and recognition eye movement patterns also did not correlate with their recognition performance. These findings suggested that perceptuomotor memory elicited by eye movement patterns during learning does not play an important role in recognition. In contrast, the retrieval of diagnostic information for recognition, such as the eyes for face recognition, is a better predictor for recognition performance. Copyright © 2017 Elsevier Ltd. All rights reserved.

  6. Fixation to features and neural processing of facial expressions in a gender discrimination task.

    Science.gov (United States)

    Neath, Karly N; Itier, Roxane J

    2015-10-01

    Early face encoding, as reflected by the N170 ERP component, is sensitive to fixation to the eyes. Whether this sensitivity varies with facial expressions of emotion and can also be seen on other ERP components such as P1 and EPN, was investigated. Using eye-tracking to manipulate fixation on facial features, we found the N170 to be the only eye-sensitive component and this was true for fearful, happy and neutral faces. A different effect of fixation to features was seen for the earlier P1 that likely reflected general sensitivity to face position. An early effect of emotion (∼120 ms) for happy faces was seen at occipital sites and was sustained until ∼350 ms post-stimulus. For fearful faces, an early effect was seen around 80 ms followed by a later effect appearing at ∼150 ms until ∼300 ms at lateral posterior sites. Results suggests that in this emotion-irrelevant gender discrimination task, processing of fearful and happy expressions occurred early and largely independently of the eye-sensitivity indexed by the N170. Processing of the two emotions involved different underlying brain networks active at different times. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Eye movements during the handwriting of words: Individually and within sentences.

    Science.gov (United States)

    Sita, Jodi C; Taylor, Katelyn A

    2015-10-01

    Handwriting, a complex motor process involves the coordination of both the upper limb and visual system. The gaze behavior that occurs during the handwriting process is an area that has been little studied. This study investigated the eye-movements of adults during writing and reading tasks. Eye and handwriting movements were recorded for six different words over three different tasks. The results compared reading and handwriting the same words, a between condition comparison and a comparison between the two handwriting tasks. Compared to reading, participants produced more fixations during handwriting tasks and the average fixation durations were longer. When reading fixations were found to be mostly around the center of word, whereas fixations when writing appear to be made for each letter in a written word and were located around the base of letters and flowed in a left to right direction. Between the two writing tasks more fixations were made when words were written individually compared to within sentences, yet fixation durations were no different. Correlation of the number of fixations made to kinematic variables revealed that horizontal size and road length held a strong correlation with the number of fixations made by participants. Copyright © 2015 Elsevier B.V. All rights reserved.

  8. Recognition of Translator Expertise using Sequences of Fixations and Keystrokes

    DEFF Research Database (Denmark)

    Gómez, Pascual Martínez; Minocha, Akshay; Huang, Jin

    2014-01-01

    Professional human translation is necessary to meet high quality standards in industry and governmental agencies. Translators engage in multiple activities during their task, and there is a need to model their behavior, with the objective to understand and optimize the translation process....... In recent years, user interfaces enabled us to record user events such as eye-movements or keystrokes. Although there have been insightful descriptive analysis of the translation process, there are multiple advantages in enabling quantitative inference. We present methods to classify sequences of fixations...... and keystrokes into activities and model translation sessions with the objective to recognize translator expertise. We show significant error reductions in the task of recognizing certified translators and their years of experience, and analyze the characterizing patterns....

  9. Pigment dispersion glaucoma induced by the chafing effect of intraocular lens haptics in Asian eyes.

    Science.gov (United States)

    Hong, Ying; Sun, Yan-Xiu; Qi, Hong; Zhou, Ji-Chao; Hao, Yan-Sheng

    2013-03-01

    To study the possible mechanism and treatment for pigment dispersion glaucoma (PDG) caused by single-piece acrylic (SPA) intraocular lens (IOL) ciliary sulcus fixation in Asian eyes. Patients referred for PDG caused by SPA IOL ciliary sulcus fixation to our hospital from April 2005 to June 2011 were included. The patients' general information, IOL type, interval between initial surgery and PDG occurrence, examination findings, antiglaucoma medicine regimen and surgical interventions were recorded. In total, six eyes from five Chinese patients were included in this study. The intraocular pressure (IOP) increased 19-30 days after cataract surgery and was not satisfactorily controlled with antiglaucoma medication. Dense pigmentation was deposited on the IOLs and on the anterior chamber angle. IOL haptic chafing was noted on the rear iris surface. IOL repositioning in the capsular bag was performed in three eyes and was combined with trabeculectomy in two eyes with progressive glaucoma. An IOL exchange with three-piece IOL ciliary sulcus fixation was performed in the other three eyes. Scanning electron microscopy of the explanted IOLs demonstrated a rough edge on the IOL haptics. SPA IOLs were not suitable for ciliary sulcus fixation. The chafing effect of the IOL haptics on the posterior iris pigment epithelium could induce PDG in Asian eyes. IOLs should be positioned in the capsular bag or a three-piece IOL should be used instead.

  10. Toward FRP-Based Brain-Machine Interfaces-Single-Trial Classification of Fixation-Related Potentials.

    Directory of Open Access Journals (Sweden)

    Andrea Finke

    Full Text Available The co-registration of eye tracking and electroencephalography provides a holistic measure of ongoing cognitive processes. Recently, fixation-related potentials have been introduced to quantify the neural activity in such bi-modal recordings. Fixation-related potentials are time-locked to fixation onsets, just like event-related potentials are locked to stimulus onsets. Compared to existing electroencephalography-based brain-machine interfaces that depend on visual stimuli, fixation-related potentials have the advantages that they can be used in free, unconstrained viewing conditions and can also be classified on a single-trial level. Thus, fixation-related potentials have the potential to allow for conceptually different brain-machine interfaces that directly interpret cortical activity related to the visual processing of specific objects. However, existing research has investigated fixation-related potentials only with very restricted and highly unnatural stimuli in simple search tasks while participant's body movements were restricted. We present a study where we relieved many of these restrictions while retaining some control by using a gaze-contingent visual search task. In our study, participants had to find a target object out of 12 complex and everyday objects presented on a screen while the electrical activity of the brain and eye movements were recorded simultaneously. Our results show that our proposed method for the classification of fixation-related potentials can clearly discriminate between fixations on relevant, non-relevant and background areas. Furthermore, we show that our classification approach generalizes not only to different test sets from the same participant, but also across participants. These results promise to open novel avenues for exploiting fixation-related potentials in electroencephalography-based brain-machine interfaces and thus providing a novel means for intuitive human-machine interaction.

  11. Eye-hand coupling during closed-loop drawing: evidence of shared motor planning?

    Science.gov (United States)

    Reina, G Anthony; Schwartz, Andrew B

    2003-04-01

    Previous paradigms have used reaching movements to study coupling of eye-hand kinematics. In the present study, we investigated eye-hand kinematics as curved trajectories were drawn at normal speeds. Eye and hand movements were tracked as a monkey traced ellipses and circles with the hand in free space while viewing the hand's position on a computer monitor. The results demonstrate that the movement of the hand was smooth and obeyed the 2/3 power law. Eye position, however, was restricted to 2-3 clusters along the hand's trajectory and fixed approximately 80% of the time in one of these clusters. The eye remained stationary as the hand moved away from the fixation for up to 200 ms and saccaded ahead of the hand position to the next fixation along the trajectory. The movement from one fixation cluster to another consistently occurred just after the tangential hand velocity had reached a local minimum, but before the next segment of the hand's trajectory began. The next fixation point was close to an area of high curvature along the hand's trajectory even though the hand had not reached that point along the path. A visuo-motor illusion of hand movement demonstrated that the eye movement was influenced by hand movement and not simply by visual input. During the task, neural activity of pre-motor cortex (area F4) was recorded using extracellular electrodes and used to construct a population vector of the hand's trajectory. The results suggest that the saccade onset is correlated in time with maximum curvature in the population vector trajectory for the hand movement. We hypothesize that eye and arm movements may have common, or shared, information in forming their motor plans.

  12. CUE: counterfeit-resistant usable eye movement-based authentication via oculomotor plant characteristics and complex eye movement patterns

    Science.gov (United States)

    Komogortsev, Oleg V.; Karpov, Alexey; Holland, Corey D.

    2012-06-01

    The widespread use of computers throughout modern society introduces the necessity for usable and counterfeit-resistant authentication methods to ensure secure access to personal resources such as bank accounts, e-mail, and social media. Current authentication methods require tedious memorization of lengthy pass phrases, are often prone to shouldersurfing, and may be easily replicated (either by counterfeiting parts of the human body or by guessing an authentication token based on readily available information). This paper describes preliminary work toward a counterfeit-resistant usable eye movement-based (CUE) authentication method. CUE does not require any passwords (improving the memorability aspect of the authentication system), and aims to provide high resistance to spoofing and shoulder-surfing by employing the combined biometric capabilities of two behavioral biometric traits: 1) oculomotor plant characteristics (OPC) which represent the internal, non-visible, anatomical structure of the eye; 2) complex eye movement patterns (CEM) which represent the strategies employed by the brain to guide visual attention. Both OPC and CEM are extracted from the eye movement signal provided by an eye tracking system. Preliminary results indicate that the fusion of OPC and CEM traits is capable of providing a 30% reduction in authentication error when compared to the authentication accuracy of individual traits.

  13. Adolescents' attention to responsibility messages in magazine alcohol advertisements: an eye-tracking approach.

    Science.gov (United States)

    Thomsen, Steven R; Fulton, Kristi

    2007-07-01

    To investigate whether adolescent readers attend to responsibility or moderation messages (e.g., "drink responsibly") included in magazine advertisements for alcoholic beverages and to assess the association between attention and the ability to accurately recall the content of these messages. An integrated head-eye tracking system (ASL Eye-TRAC 6000) was used to measure the eye movements, including fixations and fixation duration, of a group of 63 adolescents (ages 12-14 years) as they viewed six print advertisements for alcoholic beverages. Immediately after the eye-tracking sessions, participants completed a masked-recall exercise. Overall, the responsibility or moderation messages were the least frequently viewed textual or visual areas of the advertisements. Participants spent an average of only .35 seconds, or 7% of the total viewing time, fixating on each responsibility message. Beverage bottles, product logos, and cartoon illustrations were the most frequently viewed elements of the advertisements. Among those participants who fixated at least once on an advertisement's warning message, only a relatively small percentage were able to recall its general concept or restate it verbatim in the masked recall test. Voluntary responsibility or moderation messages failed to capture the attention of teenagers who participated in this study and need to be typographically modified to be more effective.

  14. Eye movement analysis of reading from computer displays, eReaders and printed books.

    Science.gov (United States)

    Zambarbieri, Daniela; Carniglia, Elena

    2012-09-01

    To compare eye movements during silent reading of three eBooks and a printed book. The three different eReading tools were a desktop PC, iPad tablet and Kindle eReader. Video-oculographic technology was used for recording eye movements. In the case of reading from the computer display the recordings were made by a video camera placed below the computer screen, whereas for reading from the iPad tablet, eReader and printed book the recording system was worn by the subject and had two cameras: one for recording the movement of the eyes and the other for recording the scene in front of the subject. Data analysis provided quantitative information in terms of number of fixations, their duration, and the direction of the movement, the latter to distinguish between fixations and regressions. Mean fixation duration was different only in reading from the computer display, and was similar for the Tablet, eReader and printed book. The percentage of regressions with respect to the total amount of fixations was comparable for eReading tools and the printed book. The analysis of eye movements during reading an eBook from different eReading tools suggests that subjects' reading behaviour is similar to reading from a printed book. © 2012 The College of Optometrists.

  15. Dogs Evaluate Threatening Facial Expressions by Their Biological Validity--Evidence from Gazing Patterns.

    Directory of Open Access Journals (Sweden)

    Sanni Somppi

    Full Text Available Appropriate response to companions' emotional signals is important for all social creatures. The emotional expressions of humans and non-human animals have analogies in their form and function, suggesting shared evolutionary roots, but very little is known about how animals other than primates view and process facial expressions. In primates, threat-related facial expressions evoke exceptional viewing patterns compared with neutral or positive stimuli. Here, we explore if domestic dogs (Canis familiaris have such an attentional bias toward threatening social stimuli and whether observed emotional expressions affect dogs' gaze fixation distribution among the facial features (eyes, midface and mouth. We recorded the voluntary eye gaze of 31 domestic dogs during viewing of facial photographs of humans and dogs with three emotional expressions (threatening, pleasant and neutral. We found that dogs' gaze fixations spread systematically among facial features. The distribution of fixations was altered by the seen expression, but eyes were the most probable targets of the first fixations and gathered longer looking durations than mouth regardless of the viewed expression. The examination of the inner facial features as a whole revealed more pronounced scanning differences among expressions. This suggests that dogs do not base their perception of facial expressions on the viewing of single structures, but the interpretation of the composition formed by eyes, midface and mouth. Dogs evaluated social threat rapidly and this evaluation led to attentional bias, which was dependent on the depicted species: threatening conspecifics' faces evoked heightened attention but threatening human faces instead an avoidance response. We propose that threatening signals carrying differential biological validity are processed via distinctive neurocognitive pathways. Both of these mechanisms may have an adaptive significance for domestic dogs. The findings provide a novel

  16. Influence of social presence on eye movements in visual search tasks.

    Science.gov (United States)

    Liu, Na; Yu, Ruifeng

    2017-12-01

    This study employed an eye-tracking technique to investigate the influence of social presence on eye movements in visual search tasks. A total of 20 male subjects performed visual search tasks in a 2 (target presence: present vs. absent) × 2 (task complexity: complex vs. simple) × 2 (social presence: alone vs. a human audience) within-subject experiment. Results indicated that the presence of an audience could evoke a social facilitation effect on response time in visual search tasks. Compared with working alone, the participants made fewer and shorter fixations, larger saccades and shorter scan path in simple search tasks and more and longer fixations, smaller saccades and longer scan path in complex search tasks when working with an audience. The saccade velocity and pupil diameter in the audience-present condition were larger than those in the working-alone condition. No significant change in target fixation number was observed between two social presence conditions. Practitioner Summary: This study employed an eye-tracking technique to examine the influence of social presence on eye movements in visual search tasks. Results clarified the variation mechanism and characteristics of oculomotor scanning induced by social presence in visual search.

  17. Survey of Ophthalmologists Regarding Practice Patterns for Dry Eye and Sjogren Syndrome.

    Science.gov (United States)

    Bunya, Vatinee Y; Fernandez, Karen B; Ying, Gui-Shuang; Massaro-Giordano, Mina; Macchi, Ilaria; Sulewski, Michael E; Hammersmith, Kristin M; Nagra, Parveen K; Rapuano, Christopher J; Orlin, Stephen E

    2018-01-15

    To survey ophthalmologists about current practice patterns regarding the evaluation of dry eye patients and referrals for a Sjogren syndrome (SS) workup. An online survey was sent to ophthalmologists affiliated with the Scheie Eye Institute or Wills Eye Hospital using REDCap in August 2015. Descriptive statistics were used to summarize the data. Four hundred seventy-four survey invitations were sent out and 101 (21%) ophthalmologists completed the survey. The common traditional dry eye test performed was corneal fluorescein staining (62%) and the most common newer dry eye test performed was tear osmolarity (18%). Half of respondents (51%) refer fewer than 5% of their dry eye patients for SS workups, with 18% reporting that they never refer any patients. The most common reasons for referrals included positive review of systems (60%), severe dry eye symptoms (51%) or ocular signs (47%), or dry eye that is refractory to treatment (42%). The majority (83%) felt that there is a need for an evidence-based standardized screening tool for dry eye patients to decide who should be referred for evaluation for SS. Ophthalmologists continue to prefer the use of traditional dry eye tests in practice, with the most common test being corneal fluorescein staining. There is an underreferral of dry eye patients for SS workups, which is contributing to the continued underdiagnosis of the disease. Most respondents felt that there was a need for an evidence-based standardized screening tool to decide which dry eye patients should be referred for SS evaluations.

  18. Perception and eye movements in simulated traffic situations.

    Science.gov (United States)

    Luoma, J

    1984-01-01

    In an experiment to simulate the perception task of a driver, subjects were shown uninterrupted series of colour slides of different kinds of highway scenes. The dependent variables were eye fixations, fixation times and conscious perceptions for the part of the traffic signs and roadside advertisements. Perceptions were achieved mostly as a result of fixation, but partly also by using peripheral vision. On the other hand fixation did not always cause perception. The lengthening of fixation time increased the number of correct perceptions. When the traffic sign and the roadside advertisement were in the same slide, the advertisement disturbed the perception of the sign, but in the daylight conditions this effect was not noticed as an alteration of the fixation of the sign, but as prevention of further information processing. The disturbing influence of the advertisement was increased by its bad information ergonomics which caused a long fixation time.

  19. A MATLAB-based eye tracking control system using non-invasive helmet head restraint in the macaque.

    Science.gov (United States)

    De Luna, Paolo; Mohamed Mustafar, Mohamed Faiz Bin; Rainer, Gregor

    2014-09-30

    Tracking eye position is vital for behavioral and neurophysiological investigations in systems and cognitive neuroscience. Infrared camera systems which are now available can be used for eye tracking without the need to surgically implant magnetic search coils. These systems are generally employed using rigid head fixation in monkeys, which maintains the eye in a constant position and facilitates eye tracking. We investigate the use of non-rigid head fixation using a helmet that constrains only general head orientation and allows some freedom of movement. We present a MATLAB software solution to gather and process eye position data, present visual stimuli, interact with various devices, provide experimenter feedback and store data for offline analysis. Our software solution achieves excellent timing performance due to the use of data streaming, instead of the traditionally employed data storage mode for processing analog eye position data. We present behavioral data from two monkeys, demonstrating that adequate performance levels can be achieved on a simple fixation paradigm and show how performance depends on parameters such as fixation window size. Our findings suggest that non-rigid head restraint can be employed for behavioral training and testing on a variety of gaze-dependent visual paradigms, reducing the need for rigid head restraint systems for some applications. While developed for macaque monkey, our system of course can work equally well for applications in human eye tracking where head constraint is undesirable. Copyright © 2014. Published by Elsevier B.V.

  20. Scene perception and memory revealed by eye movements and receiver-operating characteristic analyses: does a cultural difference truly exist?

    Science.gov (United States)

    Evans, Kris; Rotello, Caren M; Li, Xingshan; Rayner, Keith

    2009-02-01

    Cultural differences have been observed in scene perception and memory: Chinese participants purportedly attend to the background information more than did American participants. We investigated the influence of culture by recording eye movements during scene perception and while participants made recognition memory judgements. Real-world pictures with a focal object on a background were shown to both American and Chinese participants while their eye movements were recorded. Later, memory for the focal object in each scene was tested, and the relationship between the focal object (studied, new) and the background context (studied, new) was manipulated. Receiver-operating characteristic (ROC) curves show that both sensitivity and response bias were changed when objects were tested in new contexts. However, neither the decrease in accuracy nor the response bias shift differed with culture. The eye movement patterns were also similar across cultural groups. Both groups made longer and more fixations on the focal objects than on the contexts. The similarity of eye movement patterns and recognition memory behaviour suggests that both Americans and Chinese use the same strategies in scene perception and memory.

  1. Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients

    OpenAIRE

    Stonecipher, Karl G; Chia, Jenny; Onyenwenyi, Ahunna; Villanueva, Linda; Hollander, David A

    2013-01-01

    Karl G Stonecipher,1 Jenny Chia,2 Ahunna Onyenwenyi,2 Linda Villanueva,2 David A Hollander2 1TLC Laser Eye Centers, Greensboro, NC, 2Allergan, Inc., Irvine, CA, USA Background: Dry eye is a multifactorial, symptomatic disease associated with ocular surface inflammation and tear film hyperosmolarity. This study was designed to assess patterns of topical cyclosporine ophthalmic emulsion 0.05% (Restasis®) use in dry eye patients and determine if there were any differences in use based o...

  2. Nonexplicit change detection in complex dynamic settings: what eye movements reveal.

    Science.gov (United States)

    Vachon, François; Vallières, Benoît R; Jones, Dylan M; Tremblay, Sébastien

    2012-12-01

    We employed a computer-controlled command-and-control (C2) simulation and recorded eye movements to examine the extent and nature of the inability to detect critical changes in dynamic displays when change detection is implicit (i.e., requires no explicit report) to the operator's task. Change blindness-the failure to notice significant changes to a visual scene-may have dire consequences on performance in C2 and surveillance operations. Participants performed a radar-based risk-assessment task involving multiple subtasks. Although participants were not required to explicitly report critical changes to the operational display, change detection was critical in informing decision making. Participants' eye movements were used as an index of visual attention across the display. Nonfixated (i.e., unattended) changes were more likely to be missed than were fixated (i.e., attended) changes, supporting the idea that focused attention is necessary for conscious change detection. The finding of significant pupil dilation for changes undetected but fixated suggests that attended changes can nonetheless be missed because of a failure of attentional processes. Change blindness in complex dynamic displays takes the form of failures in establishing task-appropriate patterns of attentional allocation. These findings have implications in the design of change-detection support tools for dynamic displays and work procedure in C2 and surveillance.

  3. Emotion Words Affect Eye Fixations during Reading

    Science.gov (United States)

    Scott, Graham G.; O'Donnell, Patrick J.; Sereno, Sara C.

    2012-01-01

    Emotion words are generally characterized as possessing high arousal and extreme valence and have typically been investigated in paradigms in which they are presented and measured as single words. This study examined whether a word's emotional qualities influenced the time spent viewing that word in the context of normal reading. Eye movements…

  4. The Effects of Body Action and Attentive Anticipation on Oculomotor Fixation Stability

    Directory of Open Access Journals (Sweden)

    Hyosun Choi

    2011-10-01

    Full Text Available Tiny eye movements, such as micro-saccades, ocular tremor, and drifts, occur involuntarily during fixation. We found evidence that involvement of body action and anticipation of visual stimuli modulates them. While eye movements were monitored, subjects performed the working memory task with a touch-screen display in two different conditions. In the passive condition, each number was shown for 400-ms and spaced in time by 500-ms automatically. In the active condition, touching action was required to trigger the appearance of each number. The delay between the touch and stimulus onset was constant within a block as 200, 500, or 800-ms. Subjects were prompted to type in the number sequence after five numbers were shown. As a measure of fixation instability, deviation of eye position was analyzed by comparing eye positions with those during the reference interval (0∼50ms time period after the number onset. We observed two results: first, the deviation was smaller in pre-reference time than in post-reference time. Second, the deviation was smaller in the active condition. These results show that micro eye movements are influenced by attentive anticipation of upcoming events, which becomes more pronounced with bodily interactions. These findings suggest a cross-modal interaction among visual, motor, and oculomotor systems.

  5. Combined 23-gauge transconjunctival vitrectomy and scleral fixation of intraocular lens without conjunctival dissection in managing lens complications.

    Science.gov (United States)

    Yeung, Ling; Wang, Nan-Kai; Wu, Wei-Chi; Chen, Kuan-Jen

    2018-04-23

    To evaluate the safety and efficacy of combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of intraocular lens (IOL) without conjunctival dissection. A retrospective study in Chang Gung Memorial Hospital, Keelung and Taoyuan, Taiwan. Patients receiving combined 23-gauge transconjunctival pars plana vitrectomy and scleral fixation of IOL without conjunctival dissection were enrolled. The ocular findings, causes of lens complication, surgical procedures, type of IOL used, and complications were documented. We included 40 eyes from 39 patients (27 male, 12 female) with a mean age of 59.5 [standard deviation (±) 14.8] years old. The mean follow-up duration was 6.8 ± 5.4 months. The cause of lens complications was ocular trauma in 24 (60%) eyes, cataract surgery complications in 11 (28%) eyes, and spontaneous subluxation of crystalline lens in 5 (13%) eyes. The overall best corrected visual acuity (BCVA) (logMAR) improved from 1.359 ± 0.735 to 0.514 ± 0.582 (p IOL decentration was found in 3 (8%) eyes and 1 (3%) eye respectively. Combined 23-gauge transconjunctival vitrectomy and scleral fixation of IOL without conjunctival dissection is effective and safe in managing a wide variety of lens complications, with good postoperative comfort and visual recovery. Retrospective study, not applicable.

  6. Eye tracking reveals a crucial role for facial motion in recognition of faces by infants.

    Science.gov (United States)

    Xiao, Naiqi G; Quinn, Paul C; Liu, Shaoying; Ge, Liezhong; Pascalis, Olivier; Lee, Kang

    2015-06-01

    Current knowledge about face processing in infancy comes largely from studies using static face stimuli, but faces that infants see in the real world are mostly moving ones. To bridge this gap, 3-, 6-, and 9-month-old Asian infants (N = 118) were familiarized with either moving or static Asian female faces, and then their face recognition was tested with static face images. Eye-tracking methodology was used to record eye movements during the familiarization and test phases. The results showed a developmental change in eye movement patterns, but only for the moving faces. In addition, the more infants shifted their fixations across facial regions, the better their face recognition was, but only for the moving faces. The results suggest that facial movement influences the way faces are encoded from early in development. (c) 2015 APA, all rights reserved).

  7. Biomechanical Evaluation of Standard Versus Extended Proximal Fixation Olecranon Plates for Fixation of Olecranon Fractures.

    Science.gov (United States)

    Boden, Allison L; Daly, Charles A; Dalwadi, Poonam P; Boden, Stephanie A; Hutton, William C; Muppavarapu, Raghuveer C; Gottschalk, Michael B

    2018-01-01

    Small olecranon fractures present a significant challenge for fixation, which has resulted in development of plates with proximal extension. Olecranon-specific plates with proximal extensions are widely thought to offer superior fixation of small proximal fragments but have distinct disadvantages: larger dissection, increased hardware prominence, and the increased possibility of impingement. Previous biomechanical studies of olecranon fracture fixation have compared methods of fracture fixation, but to date there have been no studies defining olecranon plate fixation strength for standard versus extended olecranon plates. The purpose of this study is to evaluate the biomechanical utility of the extended plate for treatment of olecranon fractures. Sixteen matched pairs of fresh-frozen human cadaveric elbows were used. Of the 16, 8 matched pairs received a transverse osteotomy including 25% and 8 including 50% of the articular surface on the proximal fragment. One elbow from each pair was randomly assigned to a standard-length plate, and the other elbow in the pair received the extended-length plate, for fixation of the fracture. The ulnae were cyclically loaded and subsequently loaded to failure, with ultimate load, number of cycles, and gap formation recorded. There was no statistically significant difference between the standard and extended fixation plates in simple transverse fractures at either 25% or 50% from the proximal most portion of the articular surface of the olecranon. Standard fixation plates are sufficient for the fixation of small transverse fractures, but caution should be utilized particularly with comminution and nontransverse fracture patterns.

  8. Eye tracking and the translation process

    DEFF Research Database (Denmark)

    Hvelplund, Kristian Tangsgaard

    2014-01-01

    Eye tracking has become increasingly popular as a quantitative research method in translation research. This paper discusses some of the major methodological issues involved in the use of eye tracking in translation research. It focuses specifically on challenges in the analysis and interpretation...... of eye-tracking data as reflections of cognitive processes during translation. Four types of methodological issues are discussed in the paper. The first part discusses the preparatory steps that precede the actual recording of eye-tracking data. The second part examines critically the general assumptions...... linking eye movements to cognitive processing in the context of translation research. The third part of the paper discusses two popular eye-tracking measures often used in translation research, fixations and pupil size, while the fourth part proposes a method to evaluate the quality of eye-tracking data....

  9. Origins of superior dynamic visual acuity in baseball players: superior eye movements or superior image processing.

    Directory of Open Access Journals (Sweden)

    Yusuke Uchida

    Full Text Available Dynamic visual acuity (DVA is defined as the ability to discriminate the fine parts of a moving object. DVA is generally better in athletes than in non-athletes, and the better DVA of athletes has been attributed to a better ability to track moving objects. In the present study, we hypothesized that the better DVA of athletes is partly derived from better perception of moving images on the retina through some kind of perceptual learning. To test this hypothesis, we quantitatively measured DVA in baseball players and non-athletes using moving Landolt rings in two conditions. In the first experiment, the participants were allowed to move their eyes (free-eye-movement conditions, whereas in the second they were required to fixate on a fixation target (fixation conditions. The athletes displayed significantly better DVA than the non-athletes in the free-eye-movement conditions. However, there was no significant difference between the groups in the fixation conditions. These results suggest that the better DVA of athletes is primarily due to an improved ability to track moving targets with their eyes, rather than to improved perception of moving images on the retina.

  10. Origins of superior dynamic visual acuity in baseball players: superior eye movements or superior image processing.

    Science.gov (United States)

    Uchida, Yusuke; Kudoh, Daisuke; Murakami, Akira; Honda, Masaaki; Kitazawa, Shigeru

    2012-01-01

    Dynamic visual acuity (DVA) is defined as the ability to discriminate the fine parts of a moving object. DVA is generally better in athletes than in non-athletes, and the better DVA of athletes has been attributed to a better ability to track moving objects. In the present study, we hypothesized that the better DVA of athletes is partly derived from better perception of moving images on the retina through some kind of perceptual learning. To test this hypothesis, we quantitatively measured DVA in baseball players and non-athletes using moving Landolt rings in two conditions. In the first experiment, the participants were allowed to move their eyes (free-eye-movement conditions), whereas in the second they were required to fixate on a fixation target (fixation conditions). The athletes displayed significantly better DVA than the non-athletes in the free-eye-movement conditions. However, there was no significant difference between the groups in the fixation conditions. These results suggest that the better DVA of athletes is primarily due to an improved ability to track moving targets with their eyes, rather than to improved perception of moving images on the retina.

  11. Using support vector machines to identify literacy skills: Evidence from eye movements.

    Science.gov (United States)

    Lou, Ya; Liu, Yanping; Kaakinen, Johanna K; Li, Xingshan

    2017-06-01

    Is inferring readers' literacy skills possible by analyzing their eye movements during text reading? This study used Support Vector Machines (SVM) to analyze eye movement data from 61 undergraduate students who read a multiple-paragraph, multiple-topic expository text. Forward fixation time, first-pass rereading time, second-pass fixation time, and regression path reading time on different regions of the text were provided as features. The SVM classification algorithm assisted in distinguishing high-literacy-skilled readers from low-literacy-skilled readers with 80.3 % accuracy. Results demonstrate the effectiveness of combining eye tracking and machine learning techniques to detect readers with low literacy skills, and suggest that such approaches can be potentially used in predicting other cognitive abilities.

  12. Chess players' eye movements reveal rapid recognition of complex visual patterns: Evidence from a chess-related visual search task.

    Science.gov (United States)

    Sheridan, Heather; Reingold, Eyal M

    2017-03-01

    To explore the perceptual component of chess expertise, we monitored the eye movements of expert and novice chess players during a chess-related visual search task that tested anecdotal reports that a key differentiator of chess skill is the ability to visualize the complex moves of the knight piece. Specifically, chess players viewed an array of four minimized chessboards, and they rapidly searched for the target board that allowed a knight piece to reach a target square in three moves. On each trial, there was only one target board (i.e., the "Yes" board), and for the remaining "lure" boards, the knight's path was blocked on either the first move (the "Easy No" board) or the second move (i.e., "the Difficult No" board). As evidence that chess experts can rapidly differentiate complex chess-related visual patterns, the experts (but not the novices) showed longer first-fixation durations on the "Yes" board relative to the "Difficult No" board. Moreover, as hypothesized, the task strongly differentiated chess skill: Reaction times were more than four times faster for the experts relative to novices, and reaction times were correlated with within-group measures of expertise (i.e., official chess ratings, number of hours of practice). These results indicate that a key component of chess expertise is the ability to rapidly recognize complex visual patterns.

  13. Ab-interno scleral suture loop fixation with cow-hitch knot in posterior chamber intraocular lens decentration

    Directory of Open Access Journals (Sweden)

    Ertugrul Can

    2016-01-01

    Full Text Available Aim of Study: To describe a simplified ab-interno cow-hitch suture fixation technique for repositioning decentered posterior chamber intraocular lens (PC IOL. Materials and Methods: Two cases are presented with the surgical correction of decentered and subluxated IOL. Ab-interno scleral suture fixation technique with hitch-cow knot in the eye was performed with a ciliary sulcus guide instrument and 1 year follow-up was completed. Results: Both of the patients had well centered lenses postoperatively. Corrected distant and near visual acuities of the patients were improved. There was no significant postoperative complication. In the follow-up period of 1 year, no evidence of suture erosion was found. Conclusions: Ab-interno scleral suture loop fixation with hitch-cow knot in the eye was effective in repositioning decentered or subluxated PC IOLs with excellent postoperative centered lenses and visual outcomes.

  14. Does consolidation of visuospatial sequence knowledge depend on eye movements?

    Directory of Open Access Journals (Sweden)

    Daphné Coomans

    Full Text Available In the current study, we assessed whether visuospatial sequence knowledge is retained over 24 hours and whether this retention is dependent on the occurrence of eye movements. Participants performed two sessions of a serial reaction time (SRT task in which they had to manually react to the identity of a target letter pair presented in one of four locations around a fixation cross. When the letter pair 'XO' was presented, a left response had to be given, when the letter pair 'OX' was presented, a right response was required. In the Eye Movements (EM condition, eye movements were necessary to perform the task since the fixation cross and the target were separated by at least 9° visual angle. In the No Eye Movements (NEM condition, on the other hand, eye movements were minimized by keeping the distance from the fixation cross to the target below 1° visual angle and by limiting the stimulus presentation to 100 ms. Since the target identity changed randomly in both conditions, no manual response sequence was present in the task. However, target location was structured according to a deterministic sequence in both the EM and NEM condition. Learning of the target location sequence was determined at the end of the first session and 24 hours after initial learning. Results indicated that the sequence learning effect in the SRT task diminished, yet remained significant, over the 24 hour interval in both conditions. Importantly, the difference in eye movements had no impact on the transfer of sequence knowledge. These results suggest that the retention of visuospatial sequence knowledge occurs alike, irrespective of whether this knowledge is supported by eye movements or not.

  15. Head-mounted eye tracking of a chimpanzee under naturalistic conditions.

    Directory of Open Access Journals (Sweden)

    Fumihiro Kano

    Full Text Available This study offers a new method for examining the bodily, manual, and eye movements of a chimpanzee at the micro-level. A female chimpanzee wore a lightweight head-mounted eye tracker (60 Hz on her head while engaging in daily interactions with the human experimenter. The eye tracker recorded her eye movements accurately while the chimpanzee freely moved her head, hands, and body. Three video cameras recorded the bodily and manual movements of the chimpanzee from multiple angles. We examined how the chimpanzee viewed the experimenter in this interactive setting and how the eye movements were related to the ongoing interactive contexts and actions. We prepared two experimentally defined contexts in each session: a face-to-face greeting phase upon the appearance of the experimenter in the experimental room, and a subsequent face-to-face task phase that included manual gestures and fruit rewards. Overall, the general viewing pattern of the chimpanzee, measured in terms of duration of individual fixations, length of individual saccades, and total viewing duration of the experimenter's face/body, was very similar to that observed in previous eye-tracking studies that used non-interactive situations, despite the differences in the experimental settings. However, the chimpanzee viewed the experimenter and the scene objects differently depending on the ongoing context and actions. The chimpanzee viewed the experimenter's face and body during the greeting phase, but viewed the experimenter's face and hands as well as the fruit reward during the task phase. These differences can be explained by the differential bodily/manual actions produced by the chimpanzee and the experimenter during each experimental phase (i.e., greeting gestures, task cueing. Additionally, the chimpanzee's viewing pattern varied depending on the identity of the experimenter (i.e., the chimpanzee's prior experience with the experimenter. These methods and results offer new

  16. The oculomotor system of decapod cephalopods: eye muscles, eye muscle nerves, and the oculomotor neurons in the central nervous system.

    Science.gov (United States)

    Budelmann, B U; Young, J Z

    1993-04-29

    Fourteen extraocular eye muscles are described in the decapods Loligo and Sepioteuthis, and thirteen in Sepia; they are supplied by four eye muscle nerves. The main action of most of the muscles is a linear movement of the eyeball, only three muscles produce strong rotations. The arrangement, innervation and action of the decapod eye muscles are compared with those of the seven eye muscles and seven eye muscle nerves in Octopus. The extra muscles in decapods are attached to the anterior and superior faces of the eyes. At least, the anterior muscles, and presumably also the superior muscles, are concerned with convergent eye movements for binocular vision during fixation and capture of prey by the tentacles. The remaining muscles are rather similar in the two cephalopod groups. In decapods, the anterior muscles include conjunctive muscles; these cross the midline and each presumably moves both eyes at the same time during fixation. In the squids Loligo and Sepioteuthis there is an additional superior conjunctive muscle of perhaps similar function. Some of the anterior muscles are associated with a narrow moveable plate, the trochlear cartilage; it is attached to the eyeball by trochlear membranes. Centripetal cobalt fillings showed that all four eye muscle nerves have fibres that originate from somata in the ipsilateral anterior lateral pedal lobe, which is the oculomotor centre. The somata of the individual nerves show different but overlapping distributions. Bundles of small presumably afferent fibres were seen in two of the four nerves. They do not enter the anterior lateral pedal lobe but run to the ventral magnocellular lobe; some afferent fibres enter the brachio-palliovisceral connective and run perhaps as far as the palliovisceral lobe.

  17. Both lexical and non-lexical characters are processed during saccadic eye movements.

    Directory of Open Access Journals (Sweden)

    Hao Zhang

    Full Text Available On average our eyes make 3-5 saccadic movements per second when we read, although their neural mechanism is still unclear. It is generally thought that saccades help redirect the retinal fovea to specific characters and words but that actual discrimination of information only occurs during periods of fixation. Indeed, it has been proposed that there is active and selective suppression of information processing during saccades to avoid experience of blurring due to the high-speed movement. Here, using a paradigm where a string of either lexical (Chinese or non-lexical (alphabetic characters are triggered by saccadic eye movements, we show that subjects can discriminate both while making saccadic eye movement. Moreover, discrimination accuracy is significantly better for characters scanned during the saccadic movement to a fixation point than those not scanned beyond it. Our results showed that character information can be processed during the saccade, therefore saccades during reading not only function to redirect the fovea to fixate the next character or word but allow pre-processing of information from the ones adjacent to the fixation locations to help target the next most salient one. In this way saccades can not only promote continuity in reading words but also actively facilitate reading comprehension.

  18. Measures and limits of models of fixation selection.

    Directory of Open Access Journals (Sweden)

    Niklas Wilming

    Full Text Available Models of fixation selection are a central tool in the quest to understand how the human mind selects relevant information. Using this tool in the evaluation of competing claims often requires comparing different models' relative performance in predicting eye movements. However, studies use a wide variety of performance measures with markedly different properties, which makes a comparison difficult. We make three main contributions to this line of research: First we argue for a set of desirable properties, review commonly used measures, and conclude that no single measure unites all desirable properties. However the area under the ROC curve (a classification measure and the KL-divergence (a distance measure of probability distributions combine many desirable properties and allow a meaningful comparison of critical model performance. We give an analytical proof of the linearity of the ROC measure with respect to averaging over subjects and demonstrate an appropriate correction of entropy-based measures like KL-divergence for small sample sizes in the context of eye-tracking data. Second, we provide a lower bound and an upper bound of these measures, based on image-independent properties of fixation data and between subject consistency respectively. Based on these bounds it is possible to give a reference frame to judge the predictive power of a model of fixation selection. We provide open-source python code to compute the reference frame. Third, we show that the upper, between subject consistency bound holds only for models that predict averages of subject populations. Departing from this we show that incorporating subject-specific viewing behavior can generate predictions which surpass that upper bound. Taken together, these findings lay out the required information that allow a well-founded judgment of the quality of any model of fixation selection and should therefore be reported when a new model is introduced.

  19. Reading Words or Pictures: Eye Movement Patterns in Adults and Children Differ by Age Group and Receptive Language Ability

    OpenAIRE

    An, Licong; Wang, Yifang; Sun, Yadong

    2017-01-01

    This study was conducted to explore the differences in the degree of attention given to Chinese print and pictures by children and adults when they read picture books with and without Chinese words. We used an eye tracker from SensoMotoric Instruments to record the visual fixations of the subjects. The results showed that the adults paid more attention to Chinese print and looked at the print sooner than the children did. The stronger the children’s receptive language abilities were, the less...

  20. Macular sensitivity and fixation patterns in patients with autosomal dominant optic atrophy

    DEFF Research Database (Denmark)

    Rönnbäck, Cecilia; Larsen, Michael

    2014-01-01

    in the nasal macula (13.6 (± 5.7) dB versus 19.7 (± 0.7) dB) and in the central macula (14.2 (± 5.1) dB versus 19.9 (± 0.3) dB). The average sensitivity decreased with decreasing BCVA in ADOA (p ... fixation was observed in 35% of ADOA patients versus 14% of controls. Unstable fixation was found only in ADOA, where its prevalence was 7%. CONCLUSION: ADOA was associated with unstable fixation and subnormal microperimetric sensitivity, especially in the central and nasal macula where the ganglion cell...

  1. [Study on A White-Eye Pattern in Dielectric Barrier Discharge by Optical Emission Spectrum].

    Science.gov (United States)

    Zhu, Ping; Dong, Li-fang; Yang, Jing; Zhang, Yu; Zhang, Chao

    2015-06-01

    The white-eye pattern was firstly observed and investigated in a dielectric barrier discharge system in the mixture of argon and air whose content can be varied whenever necessary, and the study shows that the white-eye cell is an interleaving of three different hexagonal sub-structures: the center spot, the halo, and the ambient spots. The white-eye pattern is observed at a lower applied voltage. In this experiment, the heat capacity of water is high so that the water in water electrode is good at absorbing heat. In the process of pattern discharging the gas gap didn't increase its temperature, and the discharging phenomenon of this pattern has not changed. The temperature of the water electrodes almost keeps unchanged during the whole experiment, which is advantageous for the long-term stable measurement. Pictures recorded by ordinary camera with long exposure time in the same argon content condition show that the center spot, the halo, and the ambient spots og the white-eye pattern have different brightness, which may prove that their plasma states are different. And, it is worth noting that there are obvious differences of brightness not only on the center spot, the halo, and the ambient spots at the same pressure but also at the different pressure, which shows that its plasma state also changed with the variation of the pressure. Given this, in this experiment plasma temperatures of the central spot, halo, and ambient spots in a white-eye pattern at different gas pressure were studied by using optical emission spectra. The molecular vibration temperature is investigated by the emission spectra of nitrogen band of second positive system ( C3Πu --> B3Πg ). The electron excitation temperature is researched by the relative intensity ratio method of spectral lines of Ar I 763. 51 nm (2P6 --> 1S5) and Ar I 772. 42 nm (2P2 --> 1S3). The electronic density is investigated by the broadening of spectral line 696.5 nm. Through the analysis of experimental results, it

  2. Dissecting patterns of preparatory activity in the frontal eye fields during pursuit target selection.

    Science.gov (United States)

    Raghavan, Ramanujan T; Joshua, Mati

    2017-10-01

    We investigated the composition of preparatory activity of frontal eye field (FEF) neurons in monkeys performing a pursuit target selection task. In response to the orthogonal motion of a large and a small reward target, monkeys initiated pursuit biased toward the direction of large reward target motion. FEF neurons exhibited robust preparatory activity preceding movement initiation in this task. Preparatory activity consisted of two components, ramping activity that was constant across target selection conditions, and a flat offset in firing rates that signaled the target selection condition. Ramping activity accounted for 50% of the variance in the preparatory activity and was linked most strongly, on a trial-by-trial basis, to pursuit eye movement latency rather than to its direction or gain. The offset in firing rates that discriminated target selection conditions accounted for 25% of the variance in the preparatory activity and was commensurate with a winner-take-all representation, signaling the direction of large reward target motion rather than a representation that matched the parameters of the upcoming movement. These offer new insights into the role that the frontal eye fields play in target selection and pursuit control. They show that preparatory activity in the FEF signals more strongly when to move rather than where or how to move and suggest that structures outside the FEF augment its contributions to the target selection process. NEW & NOTEWORTHY We used the smooth eye movement pursuit system to link between patterns of preparatory activity in the frontal eye fields and movement during a target selection task. The dominant pattern was a ramping signal that did not discriminate between selection conditions and was linked, on trial-by-trial basis, to movement latency. A weaker pattern was composed of a constant signal that discriminated between selection conditions but was only weakly linked to the movement parameters. Copyright © 2017 the American

  3. Photonic Crystals with an Eye Pattern Similar to Peacock Tail Feathers

    Directory of Open Access Journals (Sweden)

    Minghui Wang

    2016-08-01

    Full Text Available A facile fabrication of photonic crystals (PCs with an eye pattern similar to peacock tail feathers has been demonstrated by self-assembly of colloidal particles in a sandwich mode. The sandwich mode is formed by superhydrophilic flat substrate sandwiching the poly(styrene-methyl methacrylate-arylic acid (Poly(St-MMA-AA latex suspension (2 wt% by the hydrophobic one. The patterns are characterized by optical microscopy images, reflection spectra, and the relative scanning electronic microscope images. This work will provide beneficial help for the understanding of the self-assembly process of colloidal crystals.

  4. [Reduction of decentration after LASIK using a modified eye tracker ring for the MEL-70 excimer laser].

    Science.gov (United States)

    Schulze, S; Nietgen, G; Sekundo, W

    2004-07-01

    The aim of this study was to determine and compare the rate of eccentric laser ablation after LASIK depending on the eye tracker ring used. All LASIK treatments were carried out using the MEL-70 flying spot excimer laser (Zeiss-Meditec, Jena). The flap was produced using a Corneal Shaper trade mark or Hansatome trade mark Microkeratome (B and L Surgical, Heidelberg). Initially we used an 11 mm eye tracker ring without hinge protector. At the end of February 2001 this ring was replaced by a 10 mm and a 9.5 mm ring with built-in hinge protector. An additional modification was introduced by us: at 1 mm separations little teeth-like spikes were engraved into the eyeward side of the ring, thus stabilising the position of the ring on the globe and allowing free liquid to flow through the spaces between each spike. The built-in calibration system of the corneal topography (TMS 3, Tomey, Erlangen) from patients with a follow-up of one month or longer was used to determine the distance between the centre of the ablation zone from the fixation point. In group I patients (old ring) 42 eyes were treated. In 4 eyes ablation was perfect, in 21 eyes the ablation centre was located 0.1 to 0.49 mm from the fixation point, in 11 eyes 0.51 to 0.99 mm and in 5 eyes 1.1 to 1.49 mm whereas one eye showed a decentred ablation of 1.53 mm. In group II (new ring) 42 eyes were investigated also. In 11 eyes ablation was perfect, in 20 eyes the ablation centre was located 0.1 to 0.49 mm from the fixation point, in 10 eyes 0.5 to 0.99 mm and one eye had an eccentric ablation of 1.28 mm from the fixation point. The further development of our eye tracker ring for the MEL-70 laser considerably reduced the rate of decentred ablations. An enhanced grip of the ring onto the globe reduces a slow slide during the laser procedure.

  5. Evaluation of pars plana sclera fixation of posterior chamber intraocular lens

    Directory of Open Access Journals (Sweden)

    Fangju Han

    2014-01-01

    Full Text Available Purpose: The purpose of this study was to evaluate the clinical efficacy and safety of modified posterior chamber intraocular lens (PCIOL implantation with transscleral fixation. Design and Setting: This is a study, which is conducted at Department of Ophthalmology, Jinan Eye Hospital, Jinan Second People′s Hospital. Materials and Methods: A total of 82 patients who were scheduled for sutured PCIOL were divided randomly into modified and conventional groups. The former underwent PCIOL through pars plana fixation with knot buried and without scleral flap and the latter underwent transscleral fixation of PCIOL in the ciliary sulcus. The main outcome measures included operative time, postoperative visual acuity, and postoperative complications. Results: The mean operative time of the modified group was 39.95 ± 5.87 min, which was significantly less than that of the conventional group (45.77 ± 5.21 min; P < 0.05. No difference was found in postoperative visual acuity between the two groups. There were no significant postoperative complications, including knot exposure, endophthalmitis, and retinal detachment in either group. The optical clamping of PCIOL was prone to occur in the conventional group. Conclusion: Modified sutured PCIOL implantation is a safe, effective, and feasible technique for the correction of aphakia in eyes without adequate posterior capsular support.

  6. Influence of age, spatial memory, and ocular fixation on localization of auditory, visual, and bimodal targets by human subjects.

    Science.gov (United States)

    Dobreva, Marina S; O'Neill, William E; Paige, Gary D

    2012-12-01

    A common complaint of the elderly is difficulty identifying and localizing auditory and visual sources, particularly in competing background noise. Spatial errors in the elderly may pose challenges and even threats to self and others during everyday activities, such as localizing sounds in a crowded room or driving in traffic. In this study, we investigated the influence of aging, spatial memory, and ocular fixation on the localization of auditory, visual, and combined auditory-visual (bimodal) targets. Head-restrained young and elderly subjects localized targets in a dark, echo-attenuated room using a manual laser pointer. Localization accuracy and precision (repeatability) were quantified for both ongoing and transient (remembered) targets at response delays up to 10 s. Because eye movements bias auditory spatial perception, localization was assessed under target fixation (eyes free, pointer guided by foveal vision) and central fixation (eyes fixed straight ahead, pointer guided by peripheral vision) conditions. Spatial localization across the frontal field in young adults demonstrated (1) horizontal overshoot and vertical undershoot for ongoing auditory targets under target fixation conditions, but near-ideal horizontal localization with central fixation; (2) accurate and precise localization of ongoing visual targets guided by foveal vision under target fixation that degraded when guided by peripheral vision during central fixation; (3) overestimation in horizontal central space (±10°) of remembered auditory, visual, and bimodal targets with increasing response delay. In comparison with young adults, elderly subjects showed (1) worse precision in most paradigms, especially when localizing with peripheral vision under central fixation; (2) greatly impaired vertical localization of auditory and bimodal targets; (3) increased horizontal overshoot in the central field for remembered visual and bimodal targets across response delays; (4) greater vulnerability to

  7. Searching for Chaos Evidence in Eye Movement Signals

    Directory of Open Access Journals (Sweden)

    Katarzyna Harezlak

    2018-01-01

    Full Text Available Most naturally-occurring physical phenomena are examples of nonlinear dynamic systems, the functioning of which attracts many researchers seeking to unveil their nature. The research presented in this paper is aimed at exploring eye movement dynamic features in terms of the existence of chaotic nature. Nonlinear time series analysis methods were used for this purpose. Two time series features were studied: fractal dimension and entropy, by utilising the embedding theory. The methods were applied to the data collected during the experiment with “jumping point” stimulus. Eye movements were registered by means of the Jazz-novo eye tracker. One thousand three hundred and ninety two (1392 time series were defined, based on the horizontal velocity of eye movements registered during imposed, prolonged fixations. In order to conduct detailed analysis of the signal and identify differences contributing to the observed patterns of behaviour in time scale, fractal dimension and entropy were evaluated in various time series intervals. The influence of the noise contained in the data and the impact of the utilized filter on the obtained results were also studied. The low pass filter was used for the purpose of noise reduction with a 50 Hz cut-off frequency, estimated by means of the Fourier transform and all concerned methods were applied to time series before and after noise reduction. These studies provided some premises, which allow perceiving eye movements as observed chaotic data: characteristic of a space-time separation plot, low and non-integer time series dimension, and the time series entropy characteristic for chaotic systems.

  8. Visual attention to emotional face in schizophrenia: an eye tracking study.

    Directory of Open Access Journals (Sweden)

    Mania Asgharpour

    2015-03-01

    Full Text Available Deficits in the processing of facial emotions have been reported extensively in patients with schizophrenia. To explore whether restricted attention is the cause of impaired emotion processing in these patients, we examined visual attention through tracking eye movements in response to emotional and neutral face stimuli in a group of patients with schizophrenia and healthy individuals. We also examined the correlation between visual attention allocation and symptoms severity in our patient group.Thirty adult patients with schizophrenia and 30 matched healthy controls participated in this study. Visual attention data were recorded while participants passively viewed emotional-neutral face pairs for 500 ms. The relationship between the visual attention and symptoms severity were assessed by the Positive and Negative Syndrome Scale (PANSS in the schizophrenia group. Repeated Measures ANOVAs were used to compare the groups.Comparing the number of fixations made during face-pairs presentation, we found that patients with schizophrenia made fewer fixations on faces, regardless of the expression of the face. Analysis of the number of fixations on negative-neutral pairs also revealed that the patients made fewer fixations on both neutral and negative faces. Analysis of number of fixations on positive-neutral pairs only showed more fixations on positive relative to neutral expressions in both groups. We found no correlations between visual attention pattern to faces and symptom severity in schizophrenic patients.The results of this study suggest that the facial recognition deficit in schizophrenia is related to decreased attention to face stimuli. Finding of no difference in visual attention for positive-neutral face pairs between the groups is in line with studies that have shown increased ability to positive emotional perception in these patients.

  9. Steady-state pattern electroretinogram and short-duration transient visual evoked potentials in glaucomatous and healthy eyes.

    Science.gov (United States)

    Amarasekera, Dilru C; Resende, Arthur F; Waisbourd, Michael; Puri, Sanjeev; Moster, Marlene R; Hark, Lisa A; Katz, L Jay; Fudemberg, Scott J; Mantravadi, Anand V

    2018-01-01

    This study evaluates two rapid electrophysiological glaucoma diagnostic tests that may add a functional perspective to glaucoma diagnosis. This study aimed to determine the ability of two office-based electrophysiological diagnostic tests, steady-state pattern electroretinogram and short-duration transient visual evoked potentials, to discern between glaucomatous and healthy eyes. This is a cross-sectional study in a hospital setting. Forty-one patients with glaucoma and 41 healthy volunteers participated in the study. Steady-state pattern electroretinogram and short-duration transient visual evoked potential testing was conducted in glaucomatous and healthy eyes. A 64-bar-size stimulus with both a low-contrast and high-contrast setting was used to compare steady-state pattern electroretinogram parameters in both groups. A low-contrast and high-contrast checkerboard stimulus was used to measure short-duration transient visual evoked potential parameters in both groups. Steady-state pattern electroretinogram parameters compared were MagnitudeD, MagnitudeD/Magnitude ratio, and the signal-to-noise ratio. Short-duration transient visual evoked potential parameters compared were amplitude and latency. MagnitudeD was significantly lower in glaucoma patients when using a low-contrast (P = 0.001) and high-contrast (P state pattern electroretinogram stimulus. MagnitudeD/Magnitude ratio and SNR were significantly lower in the glaucoma group when using a high-contrast 64-bar-size stimulus (P state pattern electroretinogram was effectively able to discern between glaucomatous and healthy eyes. Steady-state pattern electroretinogram may thus have a role as a clinically useful electrophysiological diagnostic tool. © 2017 Royal Australian and New Zealand College of Ophthalmologists.

  10. A dual visual-local feedback model of the vergence eye movement system

    NARCIS (Netherlands)

    Erkelens, C.J.

    2011-01-01

    Pure vergence movements are the eye movements that we make when we change our binocular fixation between targets differing in distance but not in direction relative to the head. Pure vergence is slow and controlled by visual feedback. Saccades are the rapid eye movements that we make between targets

  11. Pattern of neuro-opthalmic disorders in a tertiary eye centre in Nigeria

    African Journals Online (AJOL)

    Pattern of neuro-opthalmic disorders in a tertiary eye centre in Nigeria. AE Omoti, MJM Waziri-Erameh. Abstract. No Abstract. Nigrian Journal of Clinical Practice Vol. 10 (2) 2007: pp. 147-151. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT. Article Metrics.

  12. Feasibility of utilizing a commercial eye tracker to assess electronic health record use during patient simulation.

    Science.gov (United States)

    Gold, Jeffrey Allen; Stephenson, Laurel E; Gorsuch, Adriel; Parthasarathy, Keshav; Mohan, Vishnu

    2016-09-01

    Numerous reports describe unintended consequences of electronic health record implementation. Having previously described physicians' failures to recognize patient safety issues within our electronic health record simulation environment, we now report on our use of eye and screen-tracking technology to understand factors associated with poor error recognition during an intensive care unit-based electronic health record simulation. We linked performance on the simulation to standard eye and screen-tracking readouts including number of fixations, saccades, mouse clicks and screens visited. In addition, we developed an overall Composite Eye Tracking score which measured when, where and how often each safety item was viewed. For 39 participants, the Composite Eye Tracking score correlated with performance on the simulation (p = 0.004). Overall, the improved performance was associated with a pattern of rapid scanning of data manifested by increased number of screens visited (p = 0.001), mouse clicks (p = 0.03) and saccades (p = 0.004). Eye tracking can be successfully integrated into electronic health record-based simulation and provides a surrogate measure of cognitive decision making and electronic health record usability. © The Author(s) 2015.

  13. The effect of beat frequency on eye movements during free viewing.

    Science.gov (United States)

    Maróti, Emese; Knakker, Balázs; Vidnyánszky, Zoltán; Weiss, Béla

    2017-02-01

    External periodic stimuli entrain brain oscillations and affect perception and attention. It has been shown that background music can change oculomotor behavior and facilitate detection of visual objects occurring on the musical beat. However, whether musical beats in different tempi modulate information sampling differently during natural viewing remains to be explored. Here we addressed this question by investigating how listening to naturalistic drum grooves in two different tempi affects eye movements of participants viewing natural scenes on a computer screen. We found that the beat frequency of the drum grooves modulated the rate of eye movements: fixation durations were increased at the lower beat frequency (1.7Hz) as compared to the higher beat frequency (2.4Hz) and no music conditions. Correspondingly, estimated visual sampling frequency decreased as fixation durations increased with lower beat frequency. These results imply that slow musical beats can retard sampling of visual information during natural viewing by increasing fixation durations. Copyright © 2016 Elsevier Ltd. All rights reserved.

  14. Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients.

    Science.gov (United States)

    Stonecipher, Karl G; Chia, Jenny; Onyenwenyi, Ahunna; Villanueva, Linda; Hollander, David A

    2013-01-01

    Dry eye is a multifactorial, symptomatic disease associated with ocular surface inflammation and tear film hyperosmolarity. This study was designed to assess patterns of topical cyclosporine ophthalmic emulsion 0.05% (Restasis®) use in dry eye patients and determine if there were any differences in use based on whether dry eye is physician-coded as a primary or nonprimary diagnosis. Records for adult patients with a diagnosis of dry eye at an outpatient visit from January 1, 2008 to December 31, 2009 were selected from Truven Health MarketScan® Research Databases. The primary endpoint was percentage of patients with at least one primary versus no primary dry eye diagnosis who filled a topical cyclosporine prescription. Data analyzed included utilization of topical corticosteroids, oral tetracyclines, and punctal plugs. The analysis included 576,416 patients, accounting for 875,692 dry eye outpatient visits: 74.7% were female, 64.2% were ages 40-69 years, and 84.4% had at least one primary dry eye diagnosis. During 2008-2009, 15.9% of dry eye patients with a primary diagnosis versus 6.5% with no primary diagnosis filled at least one cyclosporine prescription. For patients who filled at least one prescription, the mean months' supply of cyclosporine filled over 12 months was 4.44. Overall, 33.9% of dry eye patients filled a prescription for topical cyclosporine, topical corticosteroid, or oral tetracycline over 2 years. Patients with a primary dry eye diagnosis were more likely to fill a topical cyclosporine prescription. Although inflammation is key to the pathophysiology of dry eye, most patients seeing a physician for dry eye may not receive anti-inflammatory therapies.

  15. Sutureless glueless intrascleral fixation of posterior chamber intraocular lens: Boon for aphakic

    Directory of Open Access Journals (Sweden)

    Nagendra Shekhawat

    2017-01-01

    Full Text Available Purpose: To report results of intrascleral fixation of 3-piece IOL without the help of suture and glue. Methods: Study included intrascleral fixation of haptic in 50 eyes by T-fixation technique. Preoperative and postoperative visual acuity, slit lamp and fundus examination, applanation tonometry, keratometry, biometry, optical coherence tomography, Scheimpflug imaging were done for extensive evaluation. Qualitative and quantitative data were summarized in the form of proportion and mean and standard deviation, respectively. The significance of difference was measured by Chi-square test or unpaired t-test or ANOVA whichever is appropriate. P < 0.05 was considered as statistically significant. Results: There was one case in which haptic broke during handshake maneuver and another IOL was required. Postoperative complications included corneal edema (4%, increased intraocular pressure (6%, cystoid macular edema (2%, decentration (4%, and dislocation (2%, which were all managed to the level of good visual recovery. There was no significant change in corneal astigmatism. There was significant change found in best-corrected visual acuity and uncorrected visual acuity after surgery. Conclusion: This modified technique seems to be a good alternative in IOL implantation in eyes with deficient capsules in view of the decrease in the learning time and surgical time and risk for complications.

  16. Pattern of neuro-opthalmic disorders in a tertiary eye centre in Nigeria

    African Journals Online (AJOL)

    Pattern of neuro-opthalmic disorders in a tertiary eye centre in Nigeria. AE Omoti, MJM Waziri-Erameh. Abstract. No Abstract. Nigrian Journal of Clinical Practice Vol. 10 (2) 2007: pp. 147-151. Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT · AJOL African ...

  17. Legibility difference between e-books and paper books by using an eye tracker.

    Science.gov (United States)

    Kim, Jung-Yong; Min, Seung-Nam; Subramaniyam, Murali; Cho, Young-Jin

    2014-01-01

    The aim of the study was to evaluate the difference in legibility between e-books and paper books by using an eye tracker. Eight male and eight female subjects free of eye disease participated in the experiment. The experiment was conducted using a 2 × 3 within-subject design. The book type (e-book, paper book) and font size (8 pt, 10 pt, 12 pt) were independent variables, and fixation duration time, saccade length, blink rate and subjective discomfort were dependent variables. In the results, all dependent variables showed that reading paper books provided a better experience than reading e-books did. These results indicate that the legibility of e-books needs further improvement, considering fixation duration time, saccade movement, eye fatigue, device and so on. This study evaluated the legibility difference between e-books and paper books from the viewpoint of readability, eye fatigue and subjective discomfort by using an eye tracker. The results showed that paper books provided a better experience than e-books. This indicates that the readability of e-books needs further improvement in relation to paper books.

  18. Patterning of a compound eye on an extinct dipteran wing.

    Science.gov (United States)

    Dinwiddie, April; Rachootin, Stan

    2011-04-23

    We have discovered unexpected similarities between a novel and characteristic wing organ in an extinct biting midge from Baltic amber, Eohelea petrunkevitchi, and the surface of a dipteran's compound eye. Scanning electron microscope images now reveal vestigial mechanoreceptors between the facets of the organ. We interpret Eohelea's wing organ as the blending of these two developmental systems: the formation and patterning of the cuticle in the eye and of the wing. Typically, only females in the genus carry this distinctive, highly organized structure. Two species were studied (E. petrunkevitchi and E. sinuosa), and the structure differs in form between them. We examine Eohelea's wing structures for modes of fabrication, material properties and biological functions, and the effective ecological environment in which these midges lived. We argue that the current view of the wing organ's function in stridulation has been misconstrued since it was described half a century ago.

  19. A geometric method for computing ocular kinematics and classifying gaze events using monocular remote eye tracking in a robotic environment.

    Science.gov (United States)

    Singh, Tarkeshwar; Perry, Christopher M; Herter, Troy M

    2016-01-26

    Robotic and virtual-reality systems offer tremendous potential for improving assessment and rehabilitation of neurological disorders affecting the upper extremity. A key feature of these systems is that visual stimuli are often presented within the same workspace as the hands (i.e., peripersonal space). Integrating video-based remote eye tracking with robotic and virtual-reality systems can provide an additional tool for investigating how cognitive processes influence visuomotor learning and rehabilitation of the upper extremity. However, remote eye tracking systems typically compute ocular kinematics by assuming eye movements are made in a plane with constant depth (e.g. frontal plane). When visual stimuli are presented at variable depths (e.g. transverse plane), eye movements have a vergence component that may influence reliable detection of gaze events (fixations, smooth pursuits and saccades). To our knowledge, there are no available methods to classify gaze events in the transverse plane for monocular remote eye tracking systems. Here we present a geometrical method to compute ocular kinematics from a monocular remote eye tracking system when visual stimuli are presented in the transverse plane. We then use the obtained kinematics to compute velocity-based thresholds that allow us to accurately identify onsets and offsets of fixations, saccades and smooth pursuits. Finally, we validate our algorithm by comparing the gaze events computed by the algorithm with those obtained from the eye-tracking software and manual digitization. Within the transverse plane, our algorithm reliably differentiates saccades from fixations (static visual stimuli) and smooth pursuits from saccades and fixations when visual stimuli are dynamic. The proposed methods provide advancements for examining eye movements in robotic and virtual-reality systems. Our methods can also be used with other video-based or tablet-based systems in which eye movements are performed in a peripersonal

  20. Effect of planting patterns on dinitrogen fixation of alfalfa and transfer of N fixed

    International Nuclear Information System (INIS)

    Yao Yunyin; Chen Ming; Zhang Xizhong

    1993-01-01

    Contribution of symbiotic nitrogen fixation of alfalfa grown with different planting patterns was studied in a field experiment. %Ndfa and Ndfa in alfalfa and N transferred from alfalfa in meadow fescue were examined by 2 kinds of 15 N tracer techniques. The superiority of mixed culture of legumes with grasses to monoculture was influenced by planting patterns. Biomass in a mixed culture was related to proportion of alfalfa in it. The proportion of alfalfa was in close relationship not only with ratio of their seeds, but also with planting patterns. Row seeding in mixed seeds was better than broadcasting or intercropping in hay yield, total N yield and %Ndfa and Ndfa. It was also higher than the average of corresponding item of alfalfa and meadow fescue in monoculture each equal area. There was no significantly difference (P 15 N isotope dilution method and natural 1 '5N abundance method. N in meadow fescue transferred from alfalfa could be accurately determined by 15 N isotope diffusion method, but 15 N abundance method gave underestimates, even could not examined N in grasses transferred from associated legumes

  1. An eye-tracking method to reveal the link between gazing patterns and pragmatic abilities in high functioning autism spectrum disorders

    Directory of Open Access Journals (Sweden)

    Ouriel eGrynszpan

    2015-01-01

    Full Text Available The present study illustrates the potential advantages of an eye-tracking method for exploring the association between visual scanning of faces and inferences of mental states. Participants watched short videos involving social interactions and had to explain what they had seen. The number of cognition verbs (e.g. think, believe, know in their answers were counted. Given the possible use of peripheral vision that could confound eye-tracking measures, we added a condition using a gaze-contingent viewing window: the entire visual display is blurred, expect for an area that moves with the participant’s gaze. Eleven typical adults and eleven high functioning adults with ASD were recruited. The condition employing the viewing window yielded strong correlations between the average duration of fixations, the ratio of cognition verbs and standard measures of social disabilities.

  2. Eye Movements Affect Postural Control in Young and Older Females.

    Science.gov (United States)

    Thomas, Neil M; Bampouras, Theodoros M; Donovan, Tim; Dewhurst, Susan

    2016-01-01

    Visual information is used for postural stabilization in humans. However, little is known about how eye movements prevalent in everyday life interact with the postural control system in older individuals. Therefore, the present study assessed the effects of stationary gaze fixations, smooth pursuits, and saccadic eye movements, with combinations of absent, fixed and oscillating large-field visual backgrounds to generate different forms of retinal flow, on postural control in healthy young and older females. Participants were presented with computer generated visual stimuli, whilst postural sway and gaze fixations were simultaneously assessed with a force platform and eye tracking equipment, respectively. The results showed that fixed backgrounds and stationary gaze fixations attenuated postural sway. In contrast, oscillating backgrounds and smooth pursuits increased postural sway. There were no differences regarding saccades. There were also no differences in postural sway or gaze errors between age groups in any visual condition. The stabilizing effect of the fixed visual stimuli show how retinal flow and extraocular factors guide postural adjustments. The destabilizing effect of oscillating visual backgrounds and smooth pursuits may be related to more challenging conditions for determining body shifts from retinal flow, and more complex extraocular signals, respectively. Because the older participants matched the young group's performance in all conditions, decreases of posture and gaze control during stance may not be a direct consequence of healthy aging. Further research examining extraocular and retinal mechanisms of balance control and the effects of eye movements, during locomotion, is needed to better inform fall prevention interventions.

  3. Seed coat color, weight and eye pattern inheritance in gamma-rays induced cowpea M2-mutant line

    Directory of Open Access Journals (Sweden)

    Reda M. Gaafar

    2016-06-01

    Full Text Available Gamma radiation is a very effective tool for inducing genetic variation in characters of many plants. Black seeds of M2 mutant were obtained after exposure of an Egyptian cowpea cultivar (Kaha 1 to a low dose of gamma rays. Segregation of seed coat color, weight of 100 seeds and seed eye pattern of the black seeds of this mutant line were further examined in this study. Four colors were observed for seed coat in the M3 plants ranging from cream to reddish brown and three eye patterns were distinguished from each other. SDS–PAGE of the seed storage proteins showed 18 protein bands; five of these bands disappeared in the seeds of M3 plants compared to M2 and M0 controls while other 5 protein bands were specifically observed in seeds of M3 plants. PCR analysis using twelve ISSR primers showed 47 polymorphic and 8 unique amplicons. The eight unique amplicons were characteristic of the cream coat color and brown wide eye pattern (M03-G10 while the polymorphic bands were shared by 6 coat-color groups. A PCR fragment of 850 bp was amplified, using primer HB-12, in M3-G04 which showed high-100 seed weight. These results demonstrated the mutagenic effects of gamma rays on seed coat color, weight of 100 seeds and eye pattern of cowpea M3 mutant plants.

  4. Experience with compound words influences their processing: An eye movement investigation with English compound words.

    Science.gov (United States)

    Juhasz, Barbara J

    2016-11-14

    Recording eye movements provides information on the time-course of word recognition during reading. Juhasz and Rayner [Juhasz, B. J., & Rayner, K. (2003). Investigating the effects of a set of intercorrelated variables on eye fixation durations in reading. Journal of Experimental Psychology: Learning, Memory and Cognition, 29, 1312-1318] examined the impact of five word recognition variables, including familiarity and age-of-acquisition (AoA), on fixation durations. All variables impacted fixation durations, but the time-course differed. However, the study focused on relatively short, morphologically simple words. Eye movements are also informative for examining the processing of morphologically complex words such as compound words. The present study further examined the time-course of lexical and semantic variables during morphological processing. A total of 120 English compound words that varied in familiarity, AoA, semantic transparency, lexeme meaning dominance, sensory experience rating (SER), and imageability were selected. The impact of these variables on fixation durations was examined when length, word frequency, and lexeme frequencies were controlled in a regression model. The most robust effects were found for familiarity and AoA, indicating that a reader's experience with compound words significantly impacts compound recognition. These results provide insight into semantic processing of morphologically complex words during reading.

  5. Abnormalities of fixation, saccade and pursuit in posterior cortical atrophy.

    Science.gov (United States)

    Shakespeare, Timothy J; Kaski, Diego; Yong, Keir X X; Paterson, Ross W; Slattery, Catherine F; Ryan, Natalie S; Schott, Jonathan M; Crutch, Sebastian J

    2015-07-01

    The clinico-neuroradiological syndrome posterior cortical atrophy is the cardinal 'visual dementia' and most common atypical Alzheimer's disease phenotype, offering insights into mechanisms underlying clinical heterogeneity, pathological propagation and basic visual phenomena (e.g. visual crowding). Given the extensive attention paid to patients' (higher order) perceptual function, it is surprising that there have been no systematic analyses of basic oculomotor function in this population. Here 20 patients with posterior cortical atrophy, 17 patients with typical Alzheimer's disease and 22 healthy controls completed tests of fixation, saccade (including fixation/target gap and overlap conditions) and smooth pursuit eye movements using an infrared pupil-tracking system. Participants underwent detailed neuropsychological and neurological examinations, with a proportion also undertaking brain imaging and analysis of molecular pathology. In contrast to informal clinical evaluations of oculomotor dysfunction frequency (previous studies: 38%, current clinical examination: 33%), detailed eyetracking investigations revealed eye movement abnormalities in 80% of patients with posterior cortical atrophy (compared to 17% typical Alzheimer's disease, 5% controls). The greatest differences between posterior cortical atrophy and typical Alzheimer's disease were seen in saccadic performance. Patients with posterior cortical atrophy made significantly shorter saccades especially for distant targets. They also exhibited a significant exacerbation of the normal gap/overlap effect, consistent with 'sticky fixation'. Time to reach saccadic targets was significantly associated with parietal and occipital cortical thickness measures. On fixation stability tasks, patients with typical Alzheimer's disease showed more square wave jerks whose frequency was associated with lower cerebellar grey matter volume, while patients with posterior cortical atrophy showed large saccadic intrusions

  6. Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients

    Science.gov (United States)

    Stonecipher, Karl G; Chia, Jenny; Onyenwenyi, Ahunna; Villanueva, Linda; Hollander, David A

    2013-01-01

    Background Dry eye is a multifactorial, symptomatic disease associated with ocular surface inflammation and tear film hyperosmolarity. This study was designed to assess patterns of topical cyclosporine ophthalmic emulsion 0.05% (Restasis®) use in dry eye patients and determine if there were any differences in use based on whether dry eye is physician-coded as a primary or nonprimary diagnosis. Methods Records for adult patients with a diagnosis of dry eye at an outpatient visit from January 1, 2008 to December 31, 2009 were selected from Truven Health MarketScan® Research Databases. The primary endpoint was percentage of patients with at least one primary versus no primary dry eye diagnosis who filled a topical cyclosporine prescription. Data analyzed included utilization of topical corticosteroids, oral tetracyclines, and punctal plugs. Results The analysis included 576,416 patients, accounting for 875,692 dry eye outpatient visits: 74.7% were female, 64.2% were ages 40–69 years, and 84.4% had at least one primary dry eye diagnosis. During 2008–2009, 15.9% of dry eye patients with a primary diagnosis versus 6.5% with no primary diagnosis filled at least one cyclosporine prescription. For patients who filled at least one prescription, the mean months’ supply of cyclosporine filled over 12 months was 4.44. Overall, 33.9% of dry eye patients filled a prescription for topical cyclosporine, topical corticosteroid, or oral tetracycline over 2 years. Conclusion Patients with a primary dry eye diagnosis were more likely to fill a topical cyclosporine prescription. Although inflammation is key to the pathophysiology of dry eye, most patients seeing a physician for dry eye may not receive anti-inflammatory therapies. PMID:24179335

  7. Longitudinal strain bull's eye plot patterns in patients with cardiomyopathy and concentric left ventricular hypertrophy.

    Science.gov (United States)

    Liu, Dan; Hu, Kai; Nordbeck, Peter; Ertl, Georg; Störk, Stefan; Weidemann, Frank

    2016-05-10

    Despite substantial advances in the imaging techniques and pathophysiological understanding over the last decades, identification of the underlying causes of left ventricular hypertrophy by means of echocardiographic examination remains a challenge in current clinical practice. The longitudinal strain bull's eye plot derived from 2D speckle tracking imaging offers an intuitive visual overview of the global and regional left ventricular myocardial function in a single diagram. The bull's eye mapping is clinically feasible and the plot patterns could provide clues to the etiology of cardiomyopathies. The present review summarizes the longitudinal strain, bull's eye plot features in patients with various cardiomyopathies and concentric left ventricular hypertrophy and the bull's eye plot features might serve as one of the cardiac workup steps on evaluating patients with left ventricular hypertrophy.

  8. Eye and hand movements during reconstruction of spatial memory.

    Science.gov (United States)

    Burke, Melanie R; Allen, Richard J; Gonzalez, Claudia

    2012-01-01

    Recent behavioural and biological evidence indicates common mechanisms serving working memory and attention (e.g., Awh et al, 2006 Neuroscience 139 201-208). This study explored the role of spatial attention and visual search in an adapted Corsi spatial memory task. Eye movements and touch responses were recorded from participants who recalled locations (signalled by colour or shape change) from an array presented either simultaneously or sequentially. The time delay between target presentation and recall (0, 5, or 10 s) and the number of locations to be remembered (2-5) were also manipulated. Analysis of the response phase revealed subjects were less accurate (touch data) and fixated longer (eye data) when responding to sequentially presented targets suggesting higher cognitive effort. Fixation duration on target at recall was also influenced by whether spatial location was initially signalled by colour or shape change. Finally, we found that the sequence tasks encouraged longer fixations on the signalled targets than simultaneous viewing during encoding, but no difference was observed during recall. We conclude that the attentional manipulations (colour/shape) mainly affected the eye movement parameters, whereas the memory manipulation (sequential versus simultaneous, number of items) mainly affected the performance of the hand during recall, and thus the latter is more important for ascertaining if an item is remembered or forgotten. In summary, the nature of the stimuli that is used and how it is presented play key roles in determining subject performance and behaviour during spatial memory tasks.

  9. EEG and Eye Tracking Signatures of Target Encoding during Structured Visual Search

    Directory of Open Access Journals (Sweden)

    Anne-Marie Brouwer

    2017-05-01

    Full Text Available EEG and eye tracking variables are potential sources of information about the underlying processes of target detection and storage during visual search. Fixation duration, pupil size and event related potentials (ERPs locked to the onset of fixation or saccade (saccade-related potentials, SRPs have been reported to differ dependent on whether a target or a non-target is currently fixated. Here we focus on the question of whether these variables also differ between targets that are subsequently reported (hits and targets that are not (misses. Observers were asked to scan 15 locations that were consecutively highlighted for 1 s in pseudo-random order. Highlighted locations displayed either a target or a non-target stimulus with two, three or four targets per trial. After scanning, participants indicated which locations had displayed a target. To induce memory encoding failures, participants concurrently performed an aurally presented math task (high load condition. In a low load condition, participants ignored the math task. As expected, more targets were missed in the high compared with the low load condition. For both conditions, eye tracking features distinguished better between hits and misses than between targets and non-targets (with larger pupil size and shorter fixations for missed compared with correctly encoded targets. In contrast, SRP features distinguished better between targets and non-targets than between hits and misses (with average SRPs showing larger P300 waveforms for targets than for non-targets. Single trial classification results were consistent with these averages. This work suggests complementary contributions of eye and EEG measures in potential applications to support search and detect tasks. SRPs may be useful to monitor what objects are relevant to an observer, and eye variables may indicate whether the observer should be reminded of them later.

  10. Health claims database study of cyclosporine ophthalmic emulsion treatment patterns in dry eye patients

    Directory of Open Access Journals (Sweden)

    Stonecipher KG

    2013-10-01

    Full Text Available Karl G Stonecipher,1 Jenny Chia,2 Ahunna Onyenwenyi,2 Linda Villanueva,2 David A Hollander2 1TLC Laser Eye Centers, Greensboro, NC, 2Allergan, Inc., Irvine, CA, USA Background: Dry eye is a multifactorial, symptomatic disease associated with ocular surface inflammation and tear film hyperosmolarity. This study was designed to assess patterns of topical cyclosporine ophthalmic emulsion 0.05% (Restasis® use in dry eye patients and determine if there were any differences in use based on whether dry eye is physician-coded as a primary or nonprimary diagnosis. Methods: Records for adult patients with a diagnosis of dry eye at an outpatient visit from January 1, 2008 to December 31, 2009 were selected from Truven Health MarketScan® Research Databases. The primary endpoint was percentage of patients with at least one primary versus no primary dry eye diagnosis who filled a topical cyclosporine prescription. Data analyzed included utilization of topical corticosteroids, oral tetracyclines, and punctal plugs. Results: The analysis included 576,416 patients, accounting for 875,692 dry eye outpatient visits: 74.7% were female, 64.2% were ages 40-69 years, and 84.4% had at least one primary dry eye diagnosis. During 2008–2009, 15.9% of dry eye patients with a primary diagnosis versus 6.5% with no primary diagnosis filled at least one cyclosporine prescription. For patients who filled at least one prescription, the mean months’ supply of cyclosporine filled over 12 months was 4.44. Overall, 33.9% of dry eye patients filled a prescription for topical cyclosporine, topical corticosteroid, or oral tetracycline over 2 years. Conclusion: Patients with a primary dry eye diagnosis were more likely to fill a topical cyclosporine prescription. Although inflammation is key to the pathophysiology of dry eye, most patients seeing a physician for dry eye may not receive anti-inflammatory therapies. Keywords: corticosteroids, cyclosporine, dry eye syndromes

  11. Long-term outcomes of ciliary sulcus versus capsular bag fixation of intraocular lenses in children: An ultrasound biomicroscopy study.

    Directory of Open Access Journals (Sweden)

    Yun-E Zhao

    Full Text Available To evaluate the long-term outcomes of ciliary sulcus versus capsular bag fixation of intraocular lenses (IOLs in children after pediatric cataract surgery.IOL was implanted in the ciliary sulcus in 21 eyes of 14 children, and in the capsular bag in 19 eyes of 12 children for the treatment of pediatric cataract in an institutional setting. Ultrasound biomicroscopy (UBM was performed. Main outcome measures included IOL decentration, IOL tilt, anterior chamber depth (ACD, angle-opening distance at 500 μm (AOD500, trabecular-iris angle (TIA, best-corrected visual acuity (BCVA, intraocular pressure (IOP, and incidence of postoperative complications.The mean follow-up period was 6.81 ± 1.82 years. Comparing to the capsular bag fixation group, the ciliary sulcus fixation group had higher vertical IOL decentration, horizontal IOL tilt, and vertical IOL tilt (p = 0.02, 0.01,0.01, respectively, higher incidence of iris-IOL contact and peripheral anterior synechia (p = 0.001, 0.03, respectively, smaller ACD, AOD500, and TIA (p = 0.02, 0.03, 0.04, respectively, higher mean IOP (17.10 ±6.06 mmHg vs.14.15± 4.74 mmHg, p = 0.01, and higher incidence of secondary glaucoma (28.57% vs. 10.53%, p = 0.007.There was no significant difference between the two groups with regard to the BCVA, refractive errors, incidence of myopic shift, nystagmus, strabismus, and visual axis opacity.Ciliary sulcus fixation of IOLs in pediatric eyes may increase IOL malposition and crowding of the anterior segment, and may associate with a higher risk of secondary glaucoma compared to capsular bag fixation of IOLs.

  12. Eye Movement Training and Suggested Gaze Strategies in Tunnel Vision - A Randomized and Controlled Pilot Study.

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    Iliya V Ivanov

    Full Text Available Degenerative retinal diseases, especially retinitis pigmentosa (RP, lead to severe peripheral visual field loss (tunnel vision, which impairs mobility. The lack of peripheral information leads to fewer horizontal eye movements and, thus, diminished scanning in RP patients in a natural environment walking task. This randomized controlled study aimed to improve mobility and the dynamic visual field by applying a compensatory Exploratory Saccadic Training (EST.Oculomotor responses during walking and avoiding obstacles in a controlled environment were studied before and after saccade or reading training in 25 RP patients. Eye movements were recorded using a mobile infrared eye tracker (Tobii glasses that measured a range of spatial and temporal variables. Patients were randomly assigned to two training conditions: Saccade (experimental and reading (control training. All subjects who first performed reading training underwent experimental training later (waiting list control group. To assess the effect of training on subjects, we measured performance in the training task and the following outcome variables related to daily life: Response Time (RT during exploratory saccade training, Percent Preferred Walking Speed (PPWS, the number of collisions with obstacles, eye position variability, fixation duration, and the total number of fixations including the ones in the subjects' blind area of the visual field.In the saccade training group, RTs on average decreased, while the PPWS significantly increased. The improvement persisted, as tested 6 weeks after the end of the training. On average, the eye movement range of RP patients before and after training was similar to that of healthy observers. In both, the experimental and reading training groups, we found many fixations outside the subjects' seeing visual field before and after training. The average fixation duration was significantly shorter after the training, but only in the experimental training

  13. Eye Movement Training and Suggested Gaze Strategies in Tunnel Vision - A Randomized and Controlled Pilot Study.

    Science.gov (United States)

    Ivanov, Iliya V; Mackeben, Manfred; Vollmer, Annika; Martus, Peter; Nguyen, Nhung X; Trauzettel-Klosinski, Susanne

    2016-01-01

    Degenerative retinal diseases, especially retinitis pigmentosa (RP), lead to severe peripheral visual field loss (tunnel vision), which impairs mobility. The lack of peripheral information leads to fewer horizontal eye movements and, thus, diminished scanning in RP patients in a natural environment walking task. This randomized controlled study aimed to improve mobility and the dynamic visual field by applying a compensatory Exploratory Saccadic Training (EST). Oculomotor responses during walking and avoiding obstacles in a controlled environment were studied before and after saccade or reading training in 25 RP patients. Eye movements were recorded using a mobile infrared eye tracker (Tobii glasses) that measured a range of spatial and temporal variables. Patients were randomly assigned to two training conditions: Saccade (experimental) and reading (control) training. All subjects who first performed reading training underwent experimental training later (waiting list control group). To assess the effect of training on subjects, we measured performance in the training task and the following outcome variables related to daily life: Response Time (RT) during exploratory saccade training, Percent Preferred Walking Speed (PPWS), the number of collisions with obstacles, eye position variability, fixation duration, and the total number of fixations including the ones in the subjects' blind area of the visual field. In the saccade training group, RTs on average decreased, while the PPWS significantly increased. The improvement persisted, as tested 6 weeks after the end of the training. On average, the eye movement range of RP patients before and after training was similar to that of healthy observers. In both, the experimental and reading training groups, we found many fixations outside the subjects' seeing visual field before and after training. The average fixation duration was significantly shorter after the training, but only in the experimental training condition

  14. Eye movement identification based on accumulated time feature

    Science.gov (United States)

    Guo, Baobao; Wu, Qiang; Sun, Jiande; Yan, Hua

    2017-06-01

    Eye movement is a new kind of feature for biometrical recognition, it has many advantages compared with other features such as fingerprint, face, and iris. It is not only a sort of static characteristics, but also a combination of brain activity and muscle behavior, which makes it effective to prevent spoofing attack. In addition, eye movements can be incorporated with faces, iris and other features recorded from the face region into multimode systems. In this paper, we do an exploring study on eye movement identification based on the eye movement datasets provided by Komogortsev et al. in 2011 with different classification methods. The time of saccade and fixation are extracted from the eye movement data as the eye movement features. Furthermore, the performance analysis was conducted on different classification methods such as the BP, RBF, ELMAN and SVM in order to provide a reference to the future research in this field.

  15. Examining drivers' eye glance patterns during distracted driving: Insights from scanning randomness and glance transition matrix.

    Science.gov (United States)

    Wang, Yuan; Bao, Shan; Du, Wenjun; Ye, Zhirui; Sayer, James R

    2017-12-01

    Visual attention to the driving environment is of great importance for road safety. Eye glance behavior has been used as an indicator of distracted driving. This study examined and quantified drivers' glance patterns and features during distracted driving. Data from an existing naturalistic driving study were used. Entropy rate was calculated and used to assess the randomness associated with drivers' scanning patterns. A glance-transition proportion matrix was defined to quantity visual search patterns transitioning among four main eye glance locations while driving (i.e., forward on-road, phone, mirrors and others). All measurements were calculated within a 5s time window under both cell phone and non-cell phone use conditions. Results of the glance data analyses showed different patterns between distracted and non-distracted driving, featured by a higher entropy rate value and highly biased attention transferring between forward and phone locations during distracted driving. Drivers in general had higher number of glance transitions, and their on-road glance duration was significantly shorter during distracted driving when compared to non-distracted driving. Results suggest that drivers have a higher scanning randomness/disorder level and shift their main attention from surrounding areas towards phone area when engaging in visual-manual tasks. Drivers' visual search patterns during visual-manual distraction with a high scanning randomness and a high proportion of eye glance transitions towards the location of the phone provide insight into driver distraction detection. This will help to inform the design of in-vehicle human-machine interface/systems. Copyright © 2017. Published by Elsevier Ltd.

  16. Altered brain rhythms and functional network disruptions involved in patients with generalized fixation-off epilepsy

    OpenAIRE

    Solana Sánchez, Ana Beatriz; Hernández Tamames, J.A.; Molina, E.; Martínez, K.; Pineda Pardo, José Ángel; Bruña Fernandez, Ricardo; Toledano, Rafael; San Antonio-Arce, Victoria; Garcia Morales, Irene; Gil Nagel, Antonio; Alfayate, E.; Álvarez Linera, Juan; Pozo Guerrero, Francisco del

    2012-01-01

    Fixation-off sensitivity (FOS) denotes the forms of epilepsy elicited by elimination of fixation. FOS-IGE patients are rare cases [1]. In a previous work [2] we showed that two FOS-IGE patients had different altered EEG rhythms when closing eyes; only beta band was altered in patient 1 while theta, alpha and beta were altered in patient 2. In the present work, we explain the relationship between the altered brain rhythms in these patients and the disruption in functional brain net...

  17. Differences of accommodative responses between two eyes under binocular viewing condition mediated by polarizing glasses

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    Rui-Qing Wang

    2016-04-01

    Full Text Available AIM:To study the differences of accommodative responses between the two eyes under 3 different polarized viewing conditions. METHODS:Fifteen volunteers with emmetrope were recruited into this study(aged 18~38, 6 males and 9 females. Three different viewing conditions were set up by using polarizing glasses and liquid crystal display:(1right eye could see the visual target on the screen, but left eye cannot see it;(2left eye could see the visual target on the screen, but right eye cannot see it;(3both eyes could see the target. Accommodative responses were measured by infrared auto-refractor when fixating at the target at 5, 2, 1, 0.5 and 0.33m under the above 3 viewing conditions. The differences of accommodative responses under different viewing conditions were compared by using variance analysis of repeated measuring and t test. RESULTS:Significant differences of accommodative responses between the two eyes were found under condition(1and(2at all the fixating distance. The accommodative responses in used eyes which can see the visual target were higher than in non-used eyes which cannot see the visual target(PP>0.05. CONCLUSION:Ciliary muscles in the used eyes were more relatively tonic than non-used eyes under binocular open viewing condition. The imbalance of accommodative responses between two eyes may be one of the risk factors resulting into the occurrence of myopia.

  18. Designs and Algorithms to Map Eye Tracking Data with Dynamic Multielement Moving Objects

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    Ziho Kang

    2016-01-01

    Full Text Available Design concepts and algorithms were developed to address the eye tracking analysis issues that arise when (1 participants interrogate dynamic multielement objects that can overlap on the display and (2 visual angle error of the eye trackers is incapable of providing exact eye fixation coordinates. These issues were addressed by (1 developing dynamic areas of interests (AOIs in the form of either convex or rectangular shapes to represent the moving and shape-changing multielement objects, (2 introducing the concept of AOI gap tolerance (AGT that controls the size of the AOIs to address the overlapping and visual angle error issues, and (3 finding a near optimal AGT value. The approach was tested in the context of air traffic control (ATC operations where air traffic controller specialists (ATCSs interrogated multiple moving aircraft on a radar display to detect and control the aircraft for the purpose of maintaining safe and expeditious air transportation. In addition, we show how eye tracking analysis results can differ based on how we define dynamic AOIs to determine eye fixations on moving objects. The results serve as a framework to more accurately analyze eye tracking data and to better support the analysis of human performance.

  19. Chronic Organic Solvent Exposure Changes Visual Tracking in Men and Women

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    Ana R. de Oliveira

    2017-11-01

    Full Text Available Organic solvents can change CNS sensory and motor function. Eye-movement analyses can be important tools when investigating the neurotoxic changes that result from chronic organic solvent exposure. The current research measured the eye-movement patterns of men and women with and without histories of chronic organic solvent exposure. A total of 44 volunteers between 18 and 41 years old participated in this study; 22 were men (11 exposed and 11 controls, and 22 were women (11 exposed and 11 controls. Eye movement was evaluated using a 250-Hz High-Speed Video Eye Tracker Toolbox (Cambridge Research Systems via an image of a maze. Specific body indices of exposed and non-exposed men and women were measured with an Inbody 720 to determine whether the differences in eye-movement patterns were associated with body composition. The data were analyzed using IBM SPSS Statistics version 20.0.0. The results indicated that exposed adults showed significantly more fixations (t = 3.82; p = 0.001; r = 0.51 and longer fixations (t = 4.27; p = 0.001, r = 0.54 than their non-exposed counterparts. Comparisons within men (e.g., exposed and non-exposed showed significant differences in the number of fixations (t = 2.21; p = 0.04; r = 0.20 and duration of fixations (t = 3.29; p = 0.001; r = 0.35. The same was true for exposed vs. non-exposed women, who showed significant differences in the number of fixations (t = 3.10; p = 0.001; r = 0.32 and fixation durations (t = 2.76; p = 0.01; r = 0.28. However, the results did not show significant differences between exposed women and men in the number and duration of fixations. No correlations were found between eye-movement pattern and body composition measures (p > 0.05. These results suggest that chronic organic solvent exposure affects eye movements, regardless of sex and body composition, and that eye tracking contributes to the investigation of the visual information processing disorders acquired by workers exposed to

  20. Chronic Organic Solvent Exposure Changes Visual Tracking in Men and Women.

    Science.gov (United States)

    de Oliveira, Ana R; Campos Neto, Armindo de Arruda; Bezerra de Medeiros, Paloma C; de Andrade, Michael J O; Dos Santos, Natanael A

    2017-01-01

    Organic solvents can change CNS sensory and motor function. Eye-movement analyses can be important tools when investigating the neurotoxic changes that result from chronic organic solvent exposure. The current research measured the eye-movement patterns of men and women with and without histories of chronic organic solvent exposure. A total of 44 volunteers between 18 and 41 years old participated in this study; 22 were men (11 exposed and 11 controls), and 22 were women (11 exposed and 11 controls). Eye movement was evaluated using a 250-Hz High-Speed Video Eye Tracker Toolbox (Cambridge Research Systems) via an image of a maze. Specific body indices of exposed and non-exposed men and women were measured with an Inbody 720 to determine whether the differences in eye-movement patterns were associated with body composition. The data were analyzed using IBM SPSS Statistics version 20.0.0. The results indicated that exposed adults showed significantly more fixations ( t = 3.82; p = 0.001; r = 0.51) and longer fixations ( t = 4.27; p = 0.001, r = 0.54) than their non-exposed counterparts. Comparisons within men (e.g., exposed and non-exposed) showed significant differences in the number of fixations ( t = 2.21; p = 0.04; r = 0.20) and duration of fixations ( t = 3.29; p = 0.001; r = 0.35). The same was true for exposed vs. non-exposed women, who showed significant differences in the number of fixations ( t = 3.10; p = 0.001; r = 0.32) and fixation durations ( t = 2.76; p = 0.01; r = 0.28). However, the results did not show significant differences between exposed women and men in the number and duration of fixations. No correlations were found between eye-movement pattern and body composition measures ( p > 0.05). These results suggest that chronic organic solvent exposure affects eye movements, regardless of sex and body composition, and that eye tracking contributes to the investigation of the visual information processing disorders acquired by workers exposed to

  1. A change in strategy: Static emotion recognition in Malaysian Chinese

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    Chrystalle B.Y. Tan

    2015-12-01

    Full Text Available Studies have shown that while East Asians focused on the center of the face to recognize identities, participants adapted their strategy by focusing more on the eyes to identify emotions, suggesting that the eyes may contain salient information pertaining to emotional state in Eastern cultures. However, Western Caucasians employ the same strategy by moving between the eyes and mouth to identify both identities and emotions. Malaysian Chinese have been shown to focus on the eyes and nose more than the mouth during face recognition task, which represents an intermediate between Eastern and Western looking strategies. The current study examined whether Malaysian Chinese continue to employ an intermediate strategy or shift towards an Eastern or Western pattern (by fixating more on the eyes or mouth respectively during an emotion recognition task. Participants focused more on the eyes, followed by the nose then mouth. Directing attention towards the eye region resulted in better recognition of certain own- than other-race emotions. Although the fixation patterns appear similar for both tasks, further analyses showed that fixations on the eyes were reduced whereas fixations on the nose and mouth were increased during emotion recognition, indicating that participants adapt looking strategies based on their aims.

  2. Features of Recent Codon Evolution: A Comparative Polymorphism-Fixation Study

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    Zhongming Zhao

    2010-01-01

    Full Text Available Features of amino-acid and codon changes can provide us important insights on protein evolution. So far, investigators have often examined mutation patterns at either interspecies fixed substitution or intraspecies nucleotide polymorphism level, but not both. Here, we performed a unique analysis of a combined set of intra-species polymorphisms and inter-species substitutions in human codons. Strong difference in mutational pattern was found at codon positions 1, 2, and 3 between the polymorphism and fixation data. Fixation had strong bias towards increasing the rarest codons but decreasing the most frequently used codons, suggesting that codon equilibrium has not been reached yet. We detected strong CpG effect on CG-containing codons and subsequent suppression by fixation. Finally, we detected the signature of purifying selection against A∣U dinucleotides at synonymous dicodon boundaries. Overall, fixation process could effectively and quickly correct the volatile changes introduced by polymorphisms so that codon changes could be gradual and directional and that codon composition could be kept relatively stable during evolution.

  3. Evaluation of the Tobii EyeX Eye tracking controller and Matlab toolkit for research.

    Science.gov (United States)

    Gibaldi, Agostino; Vanegas, Mauricio; Bex, Peter J; Maiello, Guido

    2017-06-01

    The Tobii Eyex Controller is a new low-cost binocular eye tracker marketed for integration in gaming and consumer applications. The manufacturers claim that the system was conceived for natural eye gaze interaction, does not require continuous recalibration, and allows moderate head movements. The Controller is provided with a SDK to foster the development of new eye tracking applications. We review the characteristics of the device for its possible use in scientific research. We develop and evaluate an open source Matlab Toolkit that can be employed to interface with the EyeX device for gaze recording in behavioral experiments. The Toolkit provides calibration procedures tailored to both binocular and monocular experiments, as well as procedures to evaluate other eye tracking devices. The observed performance of the EyeX (i.e. accuracy < 0.6°, precision < 0.25°, latency < 50 ms and sampling frequency ≈55 Hz), is sufficient for some classes of research application. The device can be successfully employed to measure fixation parameters, saccadic, smooth pursuit and vergence eye movements. However, the relatively low sampling rate and moderate precision limit the suitability of the EyeX for monitoring micro-saccadic eye movements or for real-time gaze-contingent stimulus control. For these applications, research grade, high-cost eye tracking technology may still be necessary. Therefore, despite its limitations with respect to high-end devices, the EyeX has the potential to further the dissemination of eye tracking technology to a broad audience, and could be a valuable asset in consumer and gaming applications as well as a subset of basic and clinical research settings.

  4. Saccadic Eye Movement Improves Plantar Sensation and Postural Balance in Elderly Women.

    Science.gov (United States)

    Bae, Youngsook

    2016-06-01

    Vision, proprioception and plantar sensation contribute to the control of postural balance (PB). Reduced plantar sensation alters postural response and is at an increased risk of fall, and eye movements reduce the postural sway. Therefore, the aim of this study was to study the improvement of plantar sensation and PB after saccadic eye movement (SEM) and pursuit eye movement (PEM) in community-dwelling elderly women. Participants (104 females; 75.11 ± 6.25 years) were randomly allocated into the SEM group (n = 52) and PEM groups (n = 52). The SEM group performed eye fixation and SEM for 5 minutes, and the PEM group performed eye fixation and PEM for 5 minutes. The plantar sensation was measured according to the plantar surface area of the feet in contact with the floor surface before and after the intervention. Before and after SEM and PEM with the eyes open and closed, PB was measured as the area (mm(2)), length (cm), and velocity (cm/s) of the fluctuation of the center of pressure (COP). The plantar sensation of both feet improved in both groups (p eye open and close in both groups (p < 0.01). The length and velocity of the COP significantly decreased in the SEM group compared to the PEM group (p < 0.05). In conclusion, SEM and PEM are effective interventions for improving plantar sensation and PB in elderly women, with greater PB improvement after SEM.

  5. Why Do We Move Our Eyes while Trying to Remember? The Relationship between Non-Visual Gaze Patterns and Memory

    Science.gov (United States)

    Micic, Dragana; Ehrlichman, Howard; Chen, Rebecca

    2010-01-01

    Non-visual gaze patterns (NVGPs) involve saccades and fixations that spontaneously occur in cognitive activities that are not ostensibly visual. While reasons for their appearance remain obscure, convergent empirical evidence suggests that NVGPs change according to processing requirements of tasks. We examined NVGPs in tasks with long-term memory…

  6. Reading Words or Pictures: Eye Movement Patterns in Adults and Children Differ by Age Group and Receptive Language Ability.

    Science.gov (United States)

    An, Licong; Wang, Yifang; Sun, Yadong

    2017-01-01

    This study was conducted to explore the differences in the degree of attention given to Chinese print and pictures by children and adults when they read picture books with and without Chinese words. We used an eye tracker from SensoMotoric Instruments to record the visual fixations of the subjects. The results showed that the adults paid more attention to Chinese print and looked at the print sooner than the children did. The stronger the children's receptive language abilities were, the less time it took them to view the pictures. All participants spent the same amount of time looking at the pictures whether Chinese words were present or absent.

  7. Psychopathic traits are associated with reduced attention to the eyes of emotional faces among adult male non-offenders

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    Steven Mark Gillespie

    2015-10-01

    Full Text Available Psychopathic traits are linked with impairments in emotional facial expression recognition. These impairments may, in part, reflect reduced attention to the eyes of emotional faces. Although reduced attention to the eyes has been noted among children with conduct problems and callous-unemotional traits, similar findings are yet to be found in relation to psychopathic traits among adult male participants. Here we investigated the relationship of primary (selfish, uncaring and secondary (impulsive, antisocial psychopathic traits with attention to the eyes among adult male non-offenders during an emotion recognition task. We measured the number of fixations, and overall dwell time, on the eyes and the mouth of male and female faces showing the six basic emotions at varying levels of intensity. We found no relationship of primary or secondary psychopathic traits with recognition accuracy. However, primary psychopathic traits were associated with a reduced number of fixations, and lower overall dwell time, on the eyes relative to the mouth across expressions, intensity, and sex. Furthermore, the relationship of primary psychopathic traits with attention to the eyes of angry and fearful faces was influenced by the sex and intensity of the expression. We also showed that a greater number of fixations on the eyes, relative to the mouth, was associated with increased accuracy for angry and fearful expression recognition. These results are the first to show effects of psychopathic traits on attention to the eyes of emotional faces in an adult male sample, and may support amygdala based accounts of psychopathy. These findings may also have methodological implications for clinical studies of emotion recognition.

  8. Analysis of clinical efficacy and complications of titanium mini plate internal fixation and reconstructive surgery for patients with orbital fracture

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    Yang Liu

    2016-07-01

    Full Text Available AIM: To analyze the clinical efficacy and complications of titanium mini plate internal fixation and reconstructive surgery for patients with orbital fracture. METHODS: Fifty-seven cases(60 eyeswith orbital fracture from March 2013 to April 2014 in our hospital were researched. According to the random number table method, the patients were divided into observation group(29 cases with 30 eyesand control group(28 cases with 30 eyes. The control group was treated with hydroxyapatite artificial bone plate for internal fixation, and the observation group with titanium mini plate internal fixation and reconstructive surgery. The diplopia grading, grading of ocular movement disorder before and at 1, 3mo after treatment and postoperative complications(prolapse, dislocation, infectionwere compared between the two groups. RESULTS: In both group, all the 60 eyes were healed without scar formation. The rate of diplopia grading as grade 0 1mo postoperatively of observation group and the control groups were 63% and 40%(PPPCONCLUSION: The clinical curative effect of titanium mini plate internal fixation and reconstructive surgery has a good effect for orbital fractures, which can improve the therapeutic effect and reduce the incidence of adverse reactions.

  9. Seeing via miniature eye movements: A dynamic hypothesis for vision

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    Ehud eAhissar

    2012-11-01

    Full Text Available During natural viewing, the eyes are never still. Even during fixation, miniature movements of the eyes move the retinal image across tens of foveal photoreceptors. Most theories of vision implicitly assume that the visual system ignores these movements and somehow overcomes the resulting smearing. However, evidence has accumulated to indicate that fixational eye movements cannot be ignored by the visual system if fine spatial details are to be resolved. We argue that the only way the visual system can achieve its high resolution given its fixational movements is by seeing via these movements. Seeing via eye movements also eliminates the instability of the image, which would be induced by them otherwise. Here we present a hypothesis for vision, in which coarse details are spatially-encoded in gaze-related coordinates, and fine spatial details are temporally-encoded in relative retinal coordinates. The temporal encoding presented here achieves its highest resolution by encoding along the elongated axes of simple cell receptive fields and not across these axes as suggested by spatial models of vision. According to our hypothesis, fine details of shape are encoded by inter-receptor temporal phases, texture by instantaneous intra-burst rates of individual receptors, and motion by inter-burst temporal frequencies. We further describe the ability of the visual system to readout the encoded information and recode it internally. We show how reading out of retinal signals can be facilitated by neuronal phase-locked loops (NPLLs, which lock to the retinal jitter; this locking enables recoding of motion information and temporal framing of shape and texture processing. A possible implementation of this locking-and-recoding process by specific thalamocortical loops is suggested. Overall it is suggested that high-acuity vision is based primarily on temporal mechanisms of the sort presented here and low-acuity vision is based primarily on spatial mechanisms.

  10. Isolating Discriminant Neural Activity in the Presence of Eye Movements and Concurrent Task Demands

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    Jon Touryan

    2017-07-01

    Full Text Available A growing number of studies use the combination of eye-tracking and electroencephalographic (EEG measures to explore the neural processes that underlie visual perception. In these studies, fixation-related potentials (FRPs are commonly used to quantify early and late stages of visual processing that follow the onset of each fixation. However, FRPs reflect a mixture of bottom-up (sensory-driven and top-down (goal-directed processes, in addition to eye movement artifacts and unrelated neural activity. At present there is little consensus on how to separate this evoked response into its constituent elements. In this study we sought to isolate the neural sources of target detection in the presence of eye movements and over a range of concurrent task demands. Here, participants were asked to identify visual targets (Ts amongst a grid of distractor stimuli (Ls, while simultaneously performing an auditory N-back task. To identify the discriminant activity, we used independent components analysis (ICA for the separation of EEG into neural and non-neural sources. We then further separated the neural sources, using a modified measure-projection approach, into six regions of interest (ROIs: occipital, fusiform, temporal, parietal, cingulate, and frontal cortices. Using activity from these ROIs, we identified target from non-target fixations in all participants at a level similar to other state-of-the-art classification techniques. Importantly, we isolated the time course and spectral features of this discriminant activity in each ROI. In addition, we were able to quantify the effect of cognitive load on both fixation-locked potential and classification performance across regions. Together, our results show the utility of a measure-projection approach for separating task-relevant neural activity into meaningful ROIs within more complex contexts that include eye movements.

  11. The dependencies of fronto-parietal BOLD responses evoked by covert visual search suggest eye-centred coding.

    Science.gov (United States)

    Atabaki, A; Dicke, P W; Karnath, H-O; Thier, P

    2013-04-01

    Visual scenes explored covertly are initially represented in a retinal frame of reference (FOR). On the other hand, 'later' stages of the cortical network allocating spatial attention most probably use non-retinal or non-eye-centred representations as they may ease the integration of different sensory modalities for the formation of supramodal representations of space. We tested if the cortical areas involved in shifting covert attention are based on eye-centred or non-eye-centred coding by using functional magnetic resonance imaging. Subjects were scanned while detecting a target item (a regularly oriented 'L') amidst a set of distractors (rotated 'L's). The array was centred either 5° right or left of the fixation point, independent of eye-gaze orientation, the latter varied in three steps: straight relative to the head, 10° left or 10° right. A quantitative comparison of the blood-oxygen-level-dependent (BOLD) responses for the three eye-gaze orientations revealed stronger BOLD responses in the right intraparietal sulcus (IPS) and the right frontal eye field (FEF) for search in the contralateral (i.e. left) eye-centred space, independent of whether the array was located in the right or left head-centred hemispace. The left IPS showed the reverse pattern, i.e. an activation by search in the right eye-centred hemispace. In other words, the IPS and the right FEF, members of the cortical network underlying covert search, operate in an eye-centred FOR. © 2013 Federation of European Neuroscience Societies and Blackwell Publishing Ltd.

  12. An eye movement study for identification of suitable font characters for presentation on a computer screen.

    Science.gov (United States)

    Banerjee, Jayeeta; Majumdar, Dhurjati; Majumdar, Deepti; Pal, Madhu Sudan

    2010-06-01

    We are experiencing a shifting of media: from the printed paper to the computer screen. This transition is modifying the process of how we read and understand a text. It is very difficult to conclude on suitability of font characters based upon subjective evaluation method only. Present study evaluates the effect of font type on human cognitive workload during perception of individual alphabets on a computer screen. Twenty six young subjects volunteered for this study. Here, subjects have been shown individual characters of different font types and their eye movements have been recorded. A binocular eye movement recorder was used for eye movement recording. The results showed that different eye movement parameters such as pupil diameter, number of fixations, fixation duration were less for font type Verdana. The present study recommends the use of font type Verdana for presentation of individual alphabets on various electronic displays in order to reduce cognitive workload.

  13. Early visual evoked potentials are modulated by eye position in humans induced by whole body rotations

    Directory of Open Access Journals (Sweden)

    Petit Laurent

    2004-09-01

    Full Text Available Abstract Background To reach and grasp an object in space on the basis of its image cast on the retina requires different coordinate transformations that take into account gaze and limb positioning. Eye position in the orbit influences the image's conversion from retinotopic (eye-centered coordinates to an egocentric frame necessary for guiding action. Neuroimaging studies have revealed eye position-dependent activity in extrastriate visual, parietal and frontal areas that is along the visuo-motor pathway. At the earliest vision stage, the role of the primary visual area (V1 in this process remains unclear. We used an experimental design based on pattern-onset visual evoked potentials (VEP recordings to study the effect of eye position on V1 activity in humans. Results We showed that the amplitude of the initial C1 component of VEP, acknowledged to originate in V1, was modulated by the eye position. We also established that putative spontaneous small saccades related to eccentric fixation, as well as retinal disparity cannot explain the effects of changing C1 amplitude of VEP in the present study. Conclusions The present modulation of the early component of VEP suggests an eye position-dependent activity of the human primary visual area. Our findings also evidence that cortical processes combine information about the position of the stimulus on the retinae with information about the location of the eyes in their orbit as early as the stage of primary visual area.

  14. Scleral fixation of a single-piece multifocal intraocular lens.

    Science.gov (United States)

    Can, Ertugrul; Basaran, M Resat; Gül, Adem

    2013-01-01

    We describe an ab interno technique for injector implantation of a one-piece multifocal intraocular lens (IOL). Transscleral fixation of multifocal posterior chamber IOL implantation using an injector with ab interno technique was performed in an eye of a 9-year-old girl who had undergone pars plana lensectomy 2 years before for bilateral lens subluxation with unknown etiology. No major complications were encountered during a 3-month follow-up of the patient and excellent centration was observed during the follow-up period. Her preoperative best spectacle-corrected distance visual acuity of 20/32 improved to uncorrected distance visual acuity of 20/25. Closed-loop design of IOL served the function of eyelets and position of the IOL was provided using only a 2-point fixation. Intraoperative position adjustment of the IOL provided an excellent centralization of multifocal IOL.

  15. Biome-scale nitrogen fixation strategies selected by climatic constraints on nitrogen cycle.

    Science.gov (United States)

    Sheffer, Efrat; Batterman, Sarah A; Levin, Simon A; Hedin, Lars O

    2015-11-23

    Dinitrogen fixation by plants (in symbiosis with root bacteria) is a major source of new nitrogen for land ecosystems(1). A long-standing puzzle(2) is that trees capable of nitrogen fixation are abundant in nitrogen-rich tropical forests, but absent or restricted to early successional stages in nitrogen-poor extra-tropical forests. This biome-scale pattern presents an evolutionary paradox(3), given that the physiological cost(4) of nitrogen fixation predicts the opposite pattern: fixers should be out-competed by non-fixers in nitrogen-rich conditions, but competitively superior in nitrogen-poor soils. Here we evaluate whether this paradox can be explained by the existence of different fixation strategies in tropical versus extra-tropical trees: facultative fixers (capable of downregulating fixation(5,6) by sanctioning mutualistic bacteria(7)) are common in the tropics, whereas obligate fixers (less able to downregulate fixation) dominate at higher latitudes. Using a game-theoretic approach, we assess the ecological and evolutionary conditions under which these fixation strategies emerge, and examine their dependence on climate-driven differences in the nitrogen cycle. We show that in the tropics, transient soil nitrogen deficits following disturbance and rapid tree growth favour a facultative strategy and the coexistence of fixers and non-fixers. In contrast, sustained nitrogen deficits following disturbance in extra-tropical forests favour an obligate fixation strategy, and cause fixers to be excluded in late successional stages. We conclude that biome-scale differences in the abundance of nitrogen fixers can be explained by the interaction between individual plant strategies and climatic constraints on the nitrogen cycle over evolutionary time.

  16. Herpetic Eye Disease in a Public Eye Hospital in Nigeria | Nwosu ...

    African Journals Online (AJOL)

    Objective: To determine the aetiology, pattern and complications of herpetic eye disease seen at the Guinness Eye Centre, Onitsha, Nigeria. Materials and Methods: The case files of all patients with herpetic eye disease who presented at the centre between January 1998 and December 2003 were reviewed. Information on ...

  17. Hourly laying patterns of the Pearly-eyed Thrasher (Margarops fuscatus) in Puerto Rico

    Science.gov (United States)

    Wayne Arendt

    2011-01-01

    Temporal aspects of egg deposition are important factors governing avian reproductive success. I report hourly egg-laying patterns of the Pearly-eyed Thrasher (Margarops fuscatus) in the Luquillo Experimental Forest in northeastern Puerto Rico during 1979–2000. Initiatory eggs were laid by early morning (median 5 0642 hrs, AST) and almost half of the eggs were laid by...

  18. Adult Age Differences in Eye Movements During Reading: The Evidence From Chinese.

    Science.gov (United States)

    Wang, Jingxin; Li, Lin; Li, Sha; Xie, Fang; Chang, Min; Paterson, Kevin B; White, Sarah J; McGowan, Victoria A

    2018-04-16

    Substantial evidence indicates that older readers of alphabetic languages (e.g., English and German) compensate for age-related reading difficulty by employing a more risky reading strategy in which words are skipped more frequently. The effects of healthy aging on reading behavior for nonalphabetic languages, like Chinese, are largely unknown, although this would reveal the extent to which age-related changes in reading strategy are universal. Accordingly, the present research used measures of eye movements to investigate adult age differences in Chinese reading. The eye movements of young (18-30 years) and older (60+ years) Chinese readers were recorded. The older adults exhibited typical patterns of age-related reading difficulty. But rather than employing a more risky reading strategy compared with the younger readers, the older adults read more carefully by skipping words infrequently, making shorter forward eye movements, and fixating closer to the beginnings of two-character target words in sentences. In contrast with the findings for alphabetic languages, older Chinese readers appear to compensate for age-related reading difficulty by employing a more careful reading strategy. Age-related changes in reading strategy therefore appear to be language specific, rather than universal, and may reflect the specific visual and linguistic requirements of the writing system.

  19. Observation of Eye Pattern on Super-Resolution Near-Field Structure Disk with Write-Strategy Technique

    Science.gov (United States)

    Fuji, Hiroshi; Kikukawa, Takashi; Tominaga, Junji

    2004-07-01

    Pit-edge recording at a density of 150 nm pits and spaces is carried out on a super-resolution near-field structure (super-RENS) disk with a platinum oxide layer. Pits are recorded and read using a 635-nm-wavelength laser and an objective lens with a 0.6 numerical aperture. We arrange laser pulses to correctly record the pits on the disk by a write-strategy technique. The laser-pulse figure includes a unit time of 0.25 T and intensities of Pw1, Pw2 and Pw3. After recording pits of various lengths, the observation of an eye pattern is achieved despite a pit smaller than the resolution limit. Furthermore, the eye pattern maintains its shape even though other pits fill the adjacent tracks at a track density of 600 nm. The disk can be used as a pit-edge recording system through a write-strategy technique.

  20. Dynamic eye tracking based metrics for infant gaze patterns in the face-distractor competition paradigm.

    Directory of Open Access Journals (Sweden)

    Eero Ahtola

    Full Text Available To develop new standardized eye tracking based measures and metrics for infants' gaze dynamics in the face-distractor competition paradigm.Eye tracking data were collected from two samples of healthy 7-month-old (total n = 45, as well as one sample of 5-month-old infants (n = 22 in a paradigm with a picture of a face or a non-face pattern as a central stimulus, and a geometric shape as a lateral stimulus. The data were analyzed by using conventional measures of infants' initial disengagement from the central to the lateral stimulus (i.e., saccadic reaction time and probability and, additionally, novel measures reflecting infants gaze dynamics after the initial disengagement (i.e., cumulative allocation of attention to the central vs. peripheral stimulus.The results showed that the initial saccade away from the centrally presented stimulus is followed by a rapid re-engagement of attention with the central stimulus, leading to cumulative preference for the central stimulus over the lateral stimulus over time. This pattern tended to be stronger for salient facial expressions as compared to non-face patterns, was replicable across two independent samples of 7-month-old infants, and differentiated between 7 and 5 month-old infants.The results suggest that eye tracking based assessments of infants' cumulative preference for faces over time can be readily parameterized and standardized, and may provide valuable techniques for future studies examining normative developmental changes in preference for social signals.Standardized measures of early developing face preferences may have potential to become surrogate biomarkers of neurocognitive and social development.

  1. Studying the role of vision in cycling : critique on restricting research to fixation behaviour.

    NARCIS (Netherlands)

    Schepers, J.P. Brinker, B.P.L.M. den Waard, D. de Twisk, D.A.M. Schwab, D.A.M. & Smeets, J.B.J.

    2013-01-01

    In a recent study published in Accident Analysis & Prevention, Vansteenkiste et al. (2013, http://dx.doi.org/10.1016/j.aap.2012.11.025) – as one of the first in this field – investigated the visual control of bicycle steering. They undertook the interesting task of testing cyclists’ eye fixation

  2. Gaze3DFix: Detecting 3D fixations with an ellipsoidal bounding volume.

    Science.gov (United States)

    Weber, Sascha; Schubert, Rebekka S; Vogt, Stefan; Velichkovsky, Boris M; Pannasch, Sebastian

    2017-10-26

    Nowadays, the use of eyetracking to determine 2-D gaze positions is common practice, and several approaches to the detection of 2-D fixations exist, but ready-to-use algorithms to determine eye movements in three dimensions are still missing. Here we present a dispersion-based algorithm with an ellipsoidal bounding volume that estimates 3D fixations. Therefore, 3D gaze points are obtained using a vector-based approach and are further processed with our algorithm. To evaluate the accuracy of our method, we performed experimental studies with real and virtual stimuli. We obtained good congruence between stimulus position and both the 3D gaze points and the 3D fixation locations within the tested range of 200-600 mm. The mean deviation of the 3D fixations from the stimulus positions was 17 mm for the real as well as for the virtual stimuli, with larger variances at increasing stimulus distances. The described algorithms are implemented in two dynamic linked libraries (Gaze3D.dll and Fixation3D.dll), and we provide a graphical user interface (Gaze3DFixGUI.exe) that is designed for importing 2-D binocular eyetracking data and calculating both 3D gaze points and 3D fixations using the libraries. The Gaze3DFix toolkit, including both libraries and the graphical user interface, is available as open-source software at https://github.com/applied-cognition-research/Gaze3DFix .

  3. Reading Words or Pictures: Eye Movement Patterns in Adults and Children Differ by Age Group and Receptive Language Ability

    Directory of Open Access Journals (Sweden)

    Licong An

    2017-05-01

    Full Text Available This study was conducted to explore the differences in the degree of attention given to Chinese print and pictures by children and adults when they read picture books with and without Chinese words. We used an eye tracker from SensoMotoric Instruments to record the visual fixations of the subjects. The results showed that the adults paid more attention to Chinese print and looked at the print sooner than the children did. The stronger the children’s receptive language abilities were, the less time it took them to view the pictures. All participants spent the same amount of time looking at the pictures whether Chinese words were present or absent.

  4. Stereotactic radiotherapy for choroidal melanoma: analysis of eye movement during treatment

    Energy Technology Data Exchange (ETDEWEB)

    Souza, Felipe Marques Lucas de; Gonçalves, Odair Dias; Cardoso, Simone Coutinho, E-mail: felipemlucas@poli.ufrj.br [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil); Batista, Delano V.S. [Instituto de Radioproteção e Dosimetria (IRD/CNEN-RJ), Rio de Janeiro, RJ (Brazil)

    2017-07-01

    This study aims to analyze the eye’s movement during radiotherapy treatment for choroidal melanoma, as well as the methodology used in the repositioning of the patient between treatments sessions. For this purpose, the procedures used by the hospital staff were analyzed on site and videos were recorded during the treatments. The methodology for the fixation of the eye is correct in its objective. However, the repositioning needs improvements in its reproducibility. It is recommended the study to fix the eye by the healthy eye and the feasibility study for the development of a software that assists in patient repositioning. (author)

  5. Stereotactic radiotherapy for choroidal melanoma: analysis of eye movement during treatment

    International Nuclear Information System (INIS)

    Souza, Felipe Marques Lucas de; Gonçalves, Odair Dias; Cardoso, Simone Coutinho; Batista, Delano V.S.

    2017-01-01

    This study aims to analyze the eye’s movement during radiotherapy treatment for choroidal melanoma, as well as the methodology used in the repositioning of the patient between treatments sessions. For this purpose, the procedures used by the hospital staff were analyzed on site and videos were recorded during the treatments. The methodology for the fixation of the eye is correct in its objective. However, the repositioning needs improvements in its reproducibility. It is recommended the study to fix the eye by the healthy eye and the feasibility study for the development of a software that assists in patient repositioning. (author)

  6. Stereotactic radiotherapy for choroidal melanoma: analysis of eye movement during treatment

    Science.gov (United States)

    Souza, F. M. L.; Gonçalves, O. D.; Batista, D. V. S.; Cardoso, S. C.

    2018-03-01

    This study aims to analyse the eye’s movement during radiotherapy treatment for choroidal melanoma, as well as the methodology used in the repositioning of the patient between treatments sessions. For this purpose, the procedures used by the hospital staff were analysed on site and videos were recorded during the treatments. The methodology for the fixation of the eye is correct in its objective. However, the repositioning needs improvements in its reproducibility. It is recommended the study to fix the eye by the healthy eye and the feasibility study for the development of a software that assists in patient repositioning.

  7. Eye movement instructions modulate motion illusion and body sway with Op Art.

    Science.gov (United States)

    Kapoula, Zoï; Lang, Alexandre; Vernet, Marine; Locher, Paul

    2015-01-01

    Op Art generates illusory visual motion. It has been proposed that eye movements participate in such illusion. This study examined the effect of eye movement instructions (fixation vs. free exploration) on the sensation of motion as well as the body sway of subjects viewing Op Art paintings. Twenty-eight healthy adults in orthostatic stance were successively exposed to three visual stimuli consisting of one figure representing a cross (baseline condition) and two Op Art paintings providing sense of motion in depth-Bridget Riley's Movements in Squares and Akiyoshi Kitaoka's Rollers. Before their exposure to the Op Art images, participants were instructed either to fixate at the center of the image (fixation condition) or to explore the artwork (free viewing condition). Posture was measured for 30 s per condition using a body fixed sensor (accelerometer). The major finding of this study is that the two Op Art paintings induced a larger antero-posterior body sway both in terms of speed and displacement and an increased motion illusion in the free viewing condition as compared to the fixation condition. For body sway, this effect was significant for the Riley painting, while for motion illusion this effect was significant for Kitaoka's image. These results are attributed to macro-saccades presumably occurring under free viewing instructions, and most likely to the small vergence drifts during fixations following the saccades; such movements in interaction with visual properties of each image would increase either the illusory motion sensation or the antero-posterior body sway.

  8. Eye Tracking in the Cockpit: a Review of the Relationships between Eye Movements and the Aviators Cognitive State

    Science.gov (United States)

    2014-12-01

    proportional dwell time OTW in order to assess the impact of novel cockpit instruments on situational awareness in nearby airspace (Cote, Krueger, & Simmons...frequency. In particular, Spady (1978) examined eye movements during simulated landing approach under instrument flight rules ( IFR ). Simulated turbulence...al. (2007) found that NNI varied across phases of simulated IFR flight, showing the least random (most clustered) distribution of fixations during

  9. Motorized injector-assisted intrascleral intraocular lens fixation.

    Science.gov (United States)

    Hung, Jia-Horung; Wang, Shih-Hao; Teng, Yu-Ti; Hsu, Sheng-Min

    2017-03-01

    For eyes with deficient capsular support, intraocular lens (IOL) implantation has long been a technical challenge. Recently, intrascleral fixation of the haptics of a three-piece posterior chamber IOL has become a popular option. In this procedure, externalization of the leading haptic during IOL injection is a stressful step. We present a modified technique to improve the ease and safety of this step. Our modified technique involves IOL injection with a motorized injector with several important modifications described here. With these modifications, a surgeon can easily maintain the correct orientation of the IOL in a well-controlled manner during IOL injection. The records of 13 patients who underwent this technique were retrospectively evaluated. Corrected-distance visual acuity improved significantly after surgery (pIOL decentration, or vitreous hemorrhage was noted during the follow-up period. In conclusion, the motorized injector-assisted intrascleral IOL fixation technique is a safe and effective alternative to the conventional procedure. This technique makes the process of leading haptic externalization easier and more controllable. Copyright © 2017. Published by Elsevier Taiwan.

  10. Motorized injector-assisted intrascleral intraocular lens fixation

    Directory of Open Access Journals (Sweden)

    Jia-Horung Hung

    2017-03-01

    Full Text Available For eyes with deficient capsular support, intraocular lens (IOL implantation has long been a technical challenge. Recently, intrascleral fixation of the haptics of a three-piece posterior chamber IOL has become a popular option. In this procedure, externalization of the leading haptic during IOL injection is a stressful step. We present a modified technique to improve the ease and safety of this step. Our modified technique involves IOL injection with a motorized injector with several important modifications described here. With these modifications, a surgeon can easily maintain the correct orientation of the IOL in a well-controlled manner during IOL injection. The records of 13 patients who underwent this technique were retrospectively evaluated. Corrected-distance visual acuity improved significantly after surgery (p<0.05. No postoperative retinal detachment, endophthalmitis, IOL decentration, or vitreous hemorrhage was noted during the follow-up period. In conclusion, the motorized injector-assisted intrascleral IOL fixation technique is a safe and effective alternative to the conventional procedure. This technique makes the process of leading haptic externalization easier and more controllable.

  11. Gaze shifts and fixations dominate gaze behavior of walking cats

    Science.gov (United States)

    Rivers, Trevor J.; Sirota, Mikhail G.; Guttentag, Andrew I.; Ogorodnikov, Dmitri A.; Shah, Neet A.; Beloozerova, Irina N.

    2014-01-01

    Vision is important for locomotion in complex environments. How it is used to guide stepping is not well understood. We used an eye search coil technique combined with an active marker-based head recording system to characterize the gaze patterns of cats walking over terrains of different complexity: (1) on a flat surface in the dark when no visual information was available, (2) on the flat surface in light when visual information was available but not required, (3) along the highly structured but regular and familiar surface of a horizontal ladder, a task for which visual guidance of stepping was required, and (4) along a pathway cluttered with many small stones, an irregularly structured surface that was new each day. Three cats walked in a 2.5 m corridor, and 958 passages were analyzed. Gaze activity during the time when the gaze was directed at the walking surface was subdivided into four behaviors based on speed of gaze movement along the surface: gaze shift (fast movement), gaze fixation (no movement), constant gaze (movement at the body’s speed), and slow gaze (the remainder). We found that gaze shifts and fixations dominated the cats’ gaze behavior during all locomotor tasks, jointly occupying 62–84% of the time when the gaze was directed at the surface. As visual complexity of the surface and demand on visual guidance of stepping increased, cats spent more time looking at the surface, looked closer to them, and switched between gaze behaviors more often. During both visually guided locomotor tasks, gaze behaviors predominantly followed a repeated cycle of forward gaze shift followed by fixation. We call this behavior “gaze stepping”. Each gaze shift took gaze to a site approximately 75–80 cm in front of the cat, which the cat reached in 0.7–1.2 s and 1.1–1.6 strides. Constant gaze occupied only 5–21% of the time cats spent looking at the walking surface. PMID:24973656

  12. The influence of artificial scotomas on eye movements during visual search

    NARCIS (Netherlands)

    Cornelissen, FW; Bruin, KJ; Kooijman, AC

    Purpose. Fixation durations are normally adapted to the difficulty of the foveal analysis task. We examine to what extent artificial central and peripheral visual field defects interfere with this adaptation process. Methods. Subjects performed a visual search task while their eye movements were

  13. Does conspicuity enhance distraction? Saliency and eye landing position when searching for objects.

    Science.gov (United States)

    Foulsham, Tom; Underwood, Geoffrey

    2009-06-01

    While visual saliency may sometimes capture attention, the guidance of eye movements in search is often dominated by knowledge of the target. How is the search for an object influenced by the saliency of an adjacent distractor? Participants searched for a target amongst an array of objects, with distractor saliency having an effect on response time and on the speed at which targets were found. Saliency did not predict the order in which objects in target-absent trials were fixated. The within-target landing position was distributed around a modal position close to the centre of the object. Saliency did not affect this position, the latency of the initial saccade, or the likelihood of the distractor being fixated, suggesting that saliency affects the allocation of covert attention and not just eye movements.

  14. Eye-gaze patterns as students study worked-out examples in mechanics

    Directory of Open Access Journals (Sweden)

    Brian H. Ross

    2010-10-01

    Full Text Available This study explores what introductory physics students actually look at when studying worked-out examples. Our classroom experiences indicate that introductory physics students neither discuss nor refer to the conceptual information contained in the text of worked-out examples. This study is an effort to determine to what extent students incorporate the textual information into the way they study. Student eye-gaze patterns were recorded as they studied the examples to aid them in solving a target problem. Contrary to our expectations from classroom interactions, students spent 40±3% of their gaze time reading the textual information. Their gaze patterns were also characterized by numerous jumps between corresponding mathematical and textual information, implying that they were combining information from both sources. Despite this large fraction of time spent reading the text, student recall of the conceptual information contained therein remained very poor. We also found that having a particular problem in mind had no significant effects on the gaze-patterns or conceptual information retention.

  15. Eye movement assessment of selective attentional capture by emotional pictures.

    Science.gov (United States)

    Nummenmaa, Lauri; Hyönä, Jukka; Calvo, Manuel G

    2006-05-01

    The eye-tracking method was used to assess attentional orienting to and engagement on emotional visual scenes. In Experiment 1, unpleasant, neutral, or pleasant target pictures were presented simultaneously with neutral control pictures in peripheral vision under instruction to compare pleasantness of the pictures. The probability of first fixating an emotional picture, and the frequency of subsequent fixations, were greater than those for neutral pictures. In Experiment 2, participants were instructed to avoid looking at the emotional pictures, but these were still more likely to be fixated first and gazed longer during the first-pass viewing than neutral pictures. Low-level visual features cannot explain the results. It is concluded that overt visual attention is captured by both unpleasant and pleasant emotional content. 2006 APA, all rights reserved

  16. Fixations on objects in natural scenes: dissociating importance from salience

    Directory of Open Access Journals (Sweden)

    Bernard Marius e’t Hart

    2013-07-01

    Full Text Available The relation of selective attention to understanding of natural scenes has been subject to intense behavioral research and computational modeling, and gaze is often used as a proxy for such attention. The probability of an image region to be fixated typically correlates with its contrast. However, this relation does not imply a causal role of contrast. Rather, contrast may relate to an object’s importance for a scene, which in turn drives attention. Here we operationalize importance by the probability that an observer names the object as characteristic for a scene. We modify luminance contrast of either a frequently named (common/important or a rarely named (rare/unimportant object, track the observers’ eye movements during scene viewing and ask them to provide keywords describing the scene immediately after.When no object is modified relative to the background, important objects draw more fixations than unimportant ones. Increases of contrast make an object more likely to be fixated, irrespective of whether it was important for the original scene, while decreases in contrast have little effect on fixations. Any contrast modification makes originally unimportant objects more important for the scene. Finally, important objects are fixated more centrally than unimportant objects, irrespective of contrast.Our data suggest a dissociation between object importance (relevance for the scene and salience (relevance for attention. If an object obeys natural scene statistics, important objects are also salient. However, when natural scene statistics are violated, importance and salience are differentially affected. Object salience is modulated by the expectation about object properties (e.g., formed by context or gist, and importance by the violation of such expectations. In addition, the dependence of fixated locations within an object on the object’s importance suggests an analogy to the effects of word frequency on landing positions in reading.

  17. Dynamic Eye Tracking Based Metrics for Infant Gaze Patterns in the Face-Distractor Competition Paradigm

    Science.gov (United States)

    Ahtola, Eero; Stjerna, Susanna; Yrttiaho, Santeri; Nelson, Charles A.; Leppänen, Jukka M.; Vanhatalo, Sampsa

    2014-01-01

    Objective To develop new standardized eye tracking based measures and metrics for infants’ gaze dynamics in the face-distractor competition paradigm. Method Eye tracking data were collected from two samples of healthy 7-month-old (total n = 45), as well as one sample of 5-month-old infants (n = 22) in a paradigm with a picture of a face or a non-face pattern as a central stimulus, and a geometric shape as a lateral stimulus. The data were analyzed by using conventional measures of infants’ initial disengagement from the central to the lateral stimulus (i.e., saccadic reaction time and probability) and, additionally, novel measures reflecting infants gaze dynamics after the initial disengagement (i.e., cumulative allocation of attention to the central vs. peripheral stimulus). Results The results showed that the initial saccade away from the centrally presented stimulus is followed by a rapid re-engagement of attention with the central stimulus, leading to cumulative preference for the central stimulus over the lateral stimulus over time. This pattern tended to be stronger for salient facial expressions as compared to non-face patterns, was replicable across two independent samples of 7-month-old infants, and differentiated between 7 and 5 month-old infants. Conclusion The results suggest that eye tracking based assessments of infants’ cumulative preference for faces over time can be readily parameterized and standardized, and may provide valuable techniques for future studies examining normative developmental changes in preference for social signals. Significance Standardized measures of early developing face preferences may have potential to become surrogate biomarkers of neurocognitive and social development. PMID:24845102

  18. Eye shape and the nocturnal bottleneck of mammals.

    Science.gov (United States)

    Hall, Margaret I; Kamilar, Jason M; Kirk, E Christopher

    2012-12-22

    Most vertebrate groups exhibit eye shapes that vary predictably with activity pattern. Nocturnal vertebrates typically have large corneas relative to eye size as an adaptation for increased visual sensitivity. Conversely, diurnal vertebrates generally demonstrate smaller corneas relative to eye size as an adaptation for increased visual acuity. By contrast, several studies have concluded that many mammals exhibit typical nocturnal eye shapes, regardless of activity pattern. However, a recent study has argued that new statistical methods allow eye shape to accurately predict activity patterns of mammals, including cathemeral species (animals that are equally likely to be awake and active at any time of day or night). Here, we conduct a detailed analysis of eye shape and activity pattern in mammals, using a broad comparative sample of 266 species. We find that the eye shapes of cathemeral mammals completely overlap with nocturnal and diurnal species. Additionally, most diurnal and cathemeral mammals have eye shapes that are most similar to those of nocturnal birds and lizards. The only mammalian clade that diverges from this pattern is anthropoids, which have convergently evolved eye shapes similar to those of diurnal birds and lizards. Our results provide additional evidence for a nocturnal 'bottleneck' in the early evolution of crown mammals.

  19. Percepção de expressões faciais em pessoas com esquizofrenia: movimentos oculares, sintomatologia e nível intelectual The perception of facial expressions in people with schizophrenia: eye movements, symptomatology and intelligence

    Directory of Open Access Journals (Sweden)

    Katerina Lukasova

    2007-06-01

    Full Text Available A análise dos padrões dos movimentos oculares em esquizofrênicos mostra que estes apresentam alterações próprias da doença. O objetivo foi avaliar e relacionar as propriedades dos movimentos oculares com o estado clínico e nível intelectual durante observação de faces. Foram avaliados 10 sujeitos com diagnóstico de esquizofrenia e 10 controle, pareados em função de sexo, idade e escolaridade. Foi utilizada a Escala das Síndromes Positiva e Negativa (ESPN, o Teste de Matrizes Progressivas Raven e o Penn Emotion Acuity Test. A busca visual foi registrada com programa EyeGaze®. Resultados mostram que ambos os grupos fixaram mais as faces com conteúdo emocional, sendo o número total de fixações menor entre os pacientes com esquizofrenia. A duração da fixação teve correlação inversa com a pontuação no Raven, PANSS e número de fixação. Parâmetros dos movimentos oculares se correlacionaram com a condição clínica e nível intelectual dos pacientes com esquizofrenia.Analyses of the eye movement patterns of schizophrenics show some specific characteristics underlying the illness. The objective of present study was to evaluate and correlate basic properties of the eye movements with the clinical state and intelligence during the visual scan of faces. 10 outpatient subjects with schizophrenia and 10 controls matched in gender, age and school years were evaluated. The assessment tools were the Positive and Negative Syndrome Scale (PNSS, the Raven's Progressive Matrices Test and the Penn Emotion Acuity Test. The visual scan was registered with the EyeGaze® program. Both groups showed more fixations for stimuli with emotional expression, with significantly smaller overall number of fixations for the schizophrenic subjects group. Duration of fixations was inversely correlated with score in the Raven Test, PANSS and number of fixations. The properties of the eye movements showed correlation with the clinical condition and

  20. The C4-pathway of C-fixation in Spinacea oleracea. Pt. 1

    International Nuclear Information System (INIS)

    Boecher, M.; Kluge, M.

    1977-01-01

    Spinach leaf slices readily fix 14 C supplied from a suspension medium. The pattern of label distribution after 14 C-fixation in the light depends on the pH of the suspension medium. In the range of pH 3.5 leaf slices show labelling patterns of the C 3 type as do intact leaves or leaf slices incubated with 14 CO 2 in a gas cuvette. In contrast, if the tissue slices were suspended at pH 7.5 substantially more label appears in malate and other compounds of the C 4 -pathway. Under these conditions also the malate content of the tissue increases. The addition of NaHCO 3 at pH 3.5 increases the rate of C-fixation and nearly the whole fixed carbon is metabolized in the Calvin-cycle. The C-fixation is also increased, if NaHCO 3 is added at pH 7.5. Here both, the C 3 - and the C 4 -pathway contribute to an enhancement of the C-fixation. It is assumed, that increasing amounts of bicarbonate (substrate of PEP carboxylase) become available to the cells when the pH of the external medium is raised. This could increase an operation of the C 4 -pathway of C-fixation. This view is supported by the finding, that in contrast to low pH, the C-fixation at high pH results in a dominant labelling of the C 4 -atoms of malate. (orig.) [de

  1. Fixation-free assessment of the Hirschberg ratio.

    Science.gov (United States)

    Model, Dmitri; Eizenman, Moshe; Sturm, Veit

    2010-08-01

    To describe a novel methodology by which to measure the Hirschberg ratio (HR) in infants. The methodology does not require fixation on specific points, and measurements are made while infants look naturally at a display. The HR is calculated automatically from measurements of the direction of the optical axis, the position of the pupil center, and corneal reflexes in video images from an advanced two-camera eye-tracking system. The performance of the novel fixation-free procedure (FFP) was evaluated in 43 adults by measuring the average difference and the 95% limits of agreement with the standard fixation-based procedure (FBP). Repeatability of the HR measurements was evaluated by assessing the 95% limits of agreement between two independent measurements. Performance of the FFP was also evaluated in five infants. In adults, the average HR was 12.89 +/- 1.22 degrees/mm for FFP and 12.81 +/- 1.22 degrees/mm for FBP. FFP and FBP measurements were highly correlated (r = 0.95; P limits of agreement between FFP and FBP were +/-0.86 degrees/mm. The 95% limits of agreement of repeated measurements were +/-0.66 degrees/mm for FFP and +/-0.77 degrees/mm for FBP. In infants, the 95% limits of agreement of repeated measurements by FFP were +/-0.63 degrees/mm. In adults, the FFP provides accurate measurements of the HR that are in excellent agreement with measurements by FBP. In infants, measurements of HR by FFP show the same repeatability and consistency.

  2. Improved fixation quality provided by a Bessel beacon in an adaptive optics system.

    Science.gov (United States)

    Lambert, Andrew J; Daly, Elizabeth M; Dainty, Christopher J

    2013-07-01

    We investigate whether a structured probe beam that creates the beacon for use in a retinal imaging adaptive optics system can provide useful side effects. In particular we investigate whether a Bessel beam that is seen by the subject as a set of concentric rings has a dampening effect on fixation variations of the subject under observation. This calming effect would allow longer periods of observation, particularly for patients with abnormal fixation. An experimental adaptive optics system developed for retinal imaging is used to monitor the fluctuations in aberrations for artificial and human subjects. The probe beam is alternated between a traditional beacon and one provided by a Bessel beam created by SLM. Time-frequency analysis is used to indicate the differences in power and time variation during fixation depending on whether the Bessel beam or the traditional beacon is employed. Comparison is made with the response for an artificial eye to discount systemic variations. Significant evidence is accrued to indicate the reduced fluctuations in fixation when the Bessel beam is employed to create the beacon. © 2013 The Authors Ophthalmic & Physiological Optics © 2013 The College of Optometrists.

  3. Oxytocin increases attention to the eyes and selectively enhances self-reported affective empathy for fear.

    Science.gov (United States)

    Hubble, Kelly; Daughters, Katie; Manstead, Antony S R; Rees, Aled; Thapar, Anita; van Goozen, Stephanie H M

    2017-11-01

    Oxytocin (OXT) has previously been implicated in a range of prosocial behaviors such as trust and emotion recognition. Nevertheless, recent studies have questioned the evidence for this link. In addition, there has been relatively little conclusive research on the effect of OXT on empathic ability and such studies as there are have not examined the mechanisms through which OXT might affect empathy, or whether OXT selectively facilitates empathy for specific emotions. In the current study, we used eye-tracking to assess attention to socially relevant information while participants viewed dynamic, empathy-inducing video clips, in which protagonists expressed sadness, happiness, pain or fear. In a double-blind, within-subjects, randomized control trial, 40 healthy male participants received 24 IU intranasal OXT or placebo in two identical experimental sessions, separated by a 2-week interval. OXT led to an increase in time spent fixating upon the eye-region of the protagonist's face across emotions. OXT also selectively enhanced self-reported affective empathy for fear, but did not affect cognitive or affective empathy for other emotions. Nevertheless, there was no positive relationship between eye-gaze patterns and affective empathy, suggesting that although OXT influences eye-gaze and may enhance affective empathy for fear, these two systems are independent. Future studies need to further examine the effect of OXT on eye-gaze to fully ascertain whether this can explain the improvements in emotional behavior. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Adaptation to vestibular disorientation. VII, Special effects of brief periods of visual fixation on nystagmus and sensations of turning.

    Science.gov (United States)

    1967-05-01

    The influences of (a) disorientation experience and (b) brief periods of visual still-fixation were examined in exposing figure skaters and ordinary subjects to various rates of angular acceleration. Both nystagmic eye movements and sensations of tur...

  5. Spontaneous eye movements and trait empathy predict vicarious learning of fear.

    Science.gov (United States)

    Kleberg, Johan L; Selbing, Ida; Lundqvist, Daniel; Hofvander, Björn; Olsson, Andreas

    2015-12-01

    Learning to predict dangerous outcomes is important to survival. In humans, this kind of learning is often transmitted through the observation of others' emotional responses. We analyzed eye movements during an observational/vicarious fear learning procedure, in which healthy participants (N=33) watched another individual ('learning model') receiving aversive treatment (shocks) paired with a predictive conditioned stimulus (CS+), but not a control stimulus (CS-). Participants' gaze pattern towards the model differentiated as a function of whether the CS was predictive or not of a shock to the model. Consistent with our hypothesis that the face of a conspecific in distress can act as an unconditioned stimulus (US), we found that the total fixation time at a learning model's face increased when the CS+ was shown. Furthermore, we found that the total fixation time at the CS+ during learning predicted participants' conditioned responses (CRs) at a later test in the absence of the model. We also demonstrated that trait empathy was associated with stronger CRs, and that autistic traits were positively related to autonomic reactions to watching the model receiving the aversive treatment. Our results have implications for both healthy and dysfunctional socio-emotional learning. Copyright © 2015 Elsevier B.V. All rights reserved.

  6. [Effectiveness comparison of suspension fixation plus hinged external fixator and double plate internal fixation in treatment of type C humeral intercondylar fractures].

    Science.gov (United States)

    Zhang, Jian; Lin, Xu; Zhong, Zeli; Wu, Chao; Tan, Lun

    2017-07-01

    To compare the effectiveness of suspension fixation plus hinged external fixator with double plate internal fixation in the treatment of type C humeral intercondylar fractures. Between January 2014 and April 2016, 30 patients with type C (Association for the Study of Internal Fixation, AO/ASIF) humeral intercondylar fractures were treated. Kirschner wire suspension fixation plus hinged external fixator was used in 14 cases (group A), and double plate internal fixation in 16 cases (group B). There was no significant difference in gender, age, injury cause, disease duration, injury side, and type of fracture between 2 groups ( P >0.05). There was no significant difference in operation time and hospitalization stay between 2 groups ( P >0.05). But the intraoperative blood loss in group A was significantly less than that in group B ( P internal fixation removal, the intraoperative blood loss, and VAS score at 1 day and 3 days after operation in group A were significant better than those in group B ( P external fixator and double plate internal fixation for the treatment of type C humeral intercondylar fractures have ideal outcome in elbow function. But the suspension fixation plus hinged external fixator is better than double plate internal fixation in intraoperative blood loss, postoperative VAS score, and time of internal fixation removal.

  7. Effect of rectus recession combined with the rear suspension scleral fixation in patients with restrictive strabismus caused by thyroid associated ophthalmopathy

    Directory of Open Access Journals (Sweden)

    Hai-Hua Qian

    2016-04-01

    Full Text Available AIM: To investigate the therapeutic effect of rectus recession combined with the rear suspension scleral fixation for patients with restrictive strabismus caused by thyroid associated ophthalmopathy(TAO. METHODS: The clinical data of 48 patients(71 eyeswith severe TAO were retrospective analyzed from January 2013 to January 2015.The patients with severe TAO were divided into the exophthalmos(EMgroup with 25 patients(35 eyes, compressive optic neuropathy(CONgroup with 12 patients(20 eyesand exposure keratopathy(EKgroup with 11 patients(16 eyes.The rectus recession combined with rear suspension scleral fixation treatment was performed in all patients. The visual acuity, clinical activity score(CAS, and diplopia situation of each group were recorded and compared preoperatively and at 6mo postoperatively. RESULTS: The postoperative best corrected visual acuity(BCVAof the three groups were significantly higher than those before operation(PPPPPCONCLUSION: Rectus recession combined with the rear suspension scleral fixation can help improve the restrictive strabismus caused by TAO, visual acuity, eyeballs to roll back, eliminate the diplopia and to improve the life quality of patients.

  8. Impaired eye region search accuracy in children with autistic spectrum disorders.

    Directory of Open Access Journals (Sweden)

    John R Pruett

    Full Text Available To explore mechanisms underlying reduced fixation of eyes in autism, children with autistic spectrum disorders (ASD and typically developing children were tested in five visual search experiments: simple color feature; color-shape conjunction; face in non-face objects; mouth region; and eye region. No group differences were found for reaction time profile shapes in any of the five experiments, suggesting intact basic search mechanics in children with ASD. Contrary to early reports in the literature, but consistent with other more recent findings, we observed no superiority for conjunction search in children with ASD. Importantly, children with ASD did show reduced accuracy for eye region search (p = .005, suggesting that eyes contribute less to high-level face representations in ASD or that there is an eye region-specific disruption to attentional processes engaged by search in ASD.

  9. Impaired eye region search accuracy in children with autistic spectrum disorders.

    Science.gov (United States)

    Pruett, John R; Hoertel, Sarah; Constantino, John N; Moll, Angela LaMacchia; McVey, Kelly; Squire, Emma; Feczko, Eric; Povinelli, Daniel J; Petersen, Steven E

    2013-01-01

    To explore mechanisms underlying reduced fixation of eyes in autism, children with autistic spectrum disorders (ASD) and typically developing children were tested in five visual search experiments: simple color feature; color-shape conjunction; face in non-face objects; mouth region; and eye region. No group differences were found for reaction time profile shapes in any of the five experiments, suggesting intact basic search mechanics in children with ASD. Contrary to early reports in the literature, but consistent with other more recent findings, we observed no superiority for conjunction search in children with ASD. Importantly, children with ASD did show reduced accuracy for eye region search (p = .005), suggesting that eyes contribute less to high-level face representations in ASD or that there is an eye region-specific disruption to attentional processes engaged by search in ASD.

  10. Neural processing of fearful and happy facial expressions during emotion-relevant and emotion-irrelevant tasks: a fixation-to-feature approach

    Science.gov (United States)

    Neath-Tavares, Karly N.; Itier, Roxane J.

    2017-01-01

    Research suggests an important role of the eyes and mouth for discriminating facial expressions of emotion. A gaze-contingent procedure was used to test the impact of fixation to facial features on the neural response to fearful, happy and neutral facial expressions in an emotion discrimination (Exp.1) and an oddball detection (Exp.2) task. The N170 was the only eye-sensitive ERP component, and this sensitivity did not vary across facial expressions. In both tasks, compared to neutral faces, responses to happy expressions were seen as early as 100–120ms occipitally, while responses to fearful expressions started around 150ms, on or after the N170, at both occipital and lateral-posterior sites. Analyses of scalp topographies revealed different distributions of these two emotion effects across most of the epoch. Emotion processing interacted with fixation location at different times between tasks. Results suggest a role of both the eyes and mouth in the neural processing of fearful expressions and of the mouth in the processing of happy expressions, before 350ms. PMID:27430934

  11. The Active Side of Stereopsis: Fixation Strategy and Adaptation to Natural Environments.

    Science.gov (United States)

    Gibaldi, Agostino; Canessa, Andrea; Sabatini, Silvio P

    2017-03-20

    Depth perception in near viewing strongly relies on the interpretation of binocular retinal disparity to obtain stereopsis. Statistical regularities of retinal disparities have been claimed to greatly impact on the neural mechanisms that underlie binocular vision, both to facilitate perceptual decisions and to reduce computational load. In this paper, we designed a novel and unconventional approach in order to assess the role of fixation strategy in conditioning the statistics of retinal disparity. We integrated accurate realistic three-dimensional models of natural scenes with binocular eye movement recording, to obtain accurate ground-truth statistics of retinal disparity experienced by a subject in near viewing. Our results evidence how the organization of human binocular visual system is finely adapted to the disparity statistics characterizing actual fixations, thus revealing a novel role of the active fixation strategy over the binocular visual functionality. This suggests an ecological explanation for the intrinsic preference of stereopsis for a close central object surrounded by a far background, as an early binocular aspect of the figure-ground segregation process.

  12. Dynamic scanpaths: eye movement analysis methods

    Science.gov (United States)

    Blackmon, Theodore T.; Ho, Yeuk F.; Chernyak, Dimitri A.; Azzariti, Michela; Stark, Lawrence W.

    1999-05-01

    An eye movements sequence, or scanpath, during viewing of a stationary stimulus has been described as a set of fixations onto regions-of-interest, ROIs, and the saccades or transitions between them. Such scanpaths have high similarity for the same subject and stimulus both in the spatial loci of the ROIs and their sequence; scanpaths also take place during recollection of a previously viewed stimulus, suggesting that they play a similar role in visual memory and recall.

  13. Development of Text Reading in Japanese: An Eye Movement Study

    Science.gov (United States)

    Jincho, Nobuyuki; Feng, Gary; Mazuka, Reiko

    2014-01-01

    This study examined age-group differences in eye movements among third-grade, fifth-grade, and adult Japanese readers. In Experiment 1, Japanese children, but not adults, showed a longer fixation time on logographic kanji words than on phonologically transparent hiragana words. Further, an age-group difference was found in the first fixation…

  14. The socialization effect on decision making in the Prisoner's Dilemma game: An eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Anastasia G Peshkovskaya

    Full Text Available We used a mobile eye-tracking system (in the form of glasses to study the characteristics of visual perception in decision making in the Prisoner's Dilemma game. In each experiment, one of the 12 participants was equipped with eye-tracking glasses. The experiment was conducted in three stages: an anonymous Individual Game stage against a randomly chosen partner (one of the 12 other participants of the experiment; a Socialization stage, in which the participants were divided into two groups; and a Group Game stage, in which the participants played with partners in the groups. After each round, the respondent received information about his or her personal score in the last round and the overall winner of the game at the moment. The study proves that eye-tracking systems can be used for studying the process of decision making and forecasting. The total viewing time and the time of fixation on areas corresponding to noncooperative decisions is related to the participants' overall level of cooperation. The increase in the total viewing time and the time of fixation on the areas of noncooperative choice is due to a preference for noncooperative decisions and a decrease in the overall level of cooperation. The number of fixations on the group attributes is associated with group identity, but does not necessarily lead to cooperative behavior.

  15. Modeling eye gaze patterns in clinician-patient interaction with lag sequential analysis.

    Science.gov (United States)

    Montague, Enid; Xu, Jie; Chen, Ping-Yu; Asan, Onur; Barrett, Bruce P; Chewning, Betty

    2011-10-01

    The aim of this study was to examine whether lag sequential analysis could be used to describe eye gaze orientation between clinicians and patients in the medical encounter. This topic is particularly important as new technologies are implemented into multiuser health care settings in which trust is critical and nonverbal cues are integral to achieving trust. This analysis method could lead to design guidelines for technologies and more effective assessments of interventions. Nonverbal communication patterns are important aspects of clinician-patient interactions and may affect patient outcomes. The eye gaze behaviors of clinicians and patients in 110 videotaped medical encounters were analyzed using the lag sequential method to identify significant behavior sequences. Lag sequential analysis included both event-based lag and time-based lag. Results from event-based lag analysis showed that the patient's gaze followed that of the clinician, whereas the clinician's gaze did not follow the patient's. Time-based sequential analysis showed that responses from the patient usually occurred within 2 s after the initial behavior of the clinician. Our data suggest that the clinician's gaze significantly affects the medical encounter but that the converse is not true. Findings from this research have implications for the design of clinical work systems and modeling interactions. Similar research methods could be used to identify different behavior patterns in clinical settings (physical layout, technology, etc.) to facilitate and evaluate clinical work system designs.

  16. De-warping of images and improved eye tracking for the scanning laser ophthalmoscope.

    Directory of Open Access Journals (Sweden)

    Phillip Bedggood

    Full Text Available A limitation of scanning laser ophthalmoscopy (SLO is that eye movements during the capture of each frame distort the retinal image. Various sophisticated strategies have been devised to ensure that each acquired frame can be mapped quickly and accurately onto a chosen reference frame, but such methods are blind to distortions in the reference frame itself. Here we explore a method to address this limitation in software, and demonstrate its accuracy. We used high-speed (200 fps, high-resolution (~1 μm, flood-based imaging of the human retina with adaptive optics to obtain "ground truth" information on the retinal image and motion of the eye. This information was used to simulate SLO video sequences at 20 fps, allowing us to compare various methods for eye-motion recovery and subsequent minimization of intra-frame distortion. We show that a a single frame can be near-perfectly recovered with perfect knowledge of intra-frame eye motion; b eye motion at a given time point within a frame can be accurately recovered by tracking the same strip of tissue across many frames, due to the stochastic symmetry of fixational eye movements. This approach is similar to, and easily adapted from, previously suggested strip-registration approaches; c quality of frame recovery decreases with amplitude of eye movements, however, the proposed method is affected less by this than other state-of-the-art methods and so offers even greater advantages when fixation is poor. The new method could easily be integrated into existing image processing software, and we provide an example implementation written in Matlab.

  17. Influence of Vehicle Speed on the Characteristics of Driver's Eye Movement at a Highway Tunnel Entrance during Day and Night Conditions: A Pilot Study.

    Science.gov (United States)

    Qin, Li; Dong, Li-Li; Xu, Wen-Hai; Zhang, Li-Dong; Leon, Arturo S

    2018-04-02

    The aim of this study was to investigate how vehicle speed influences the characteristics of driver's eye movement at highway tunnel entrances during day and night. In this study, six drivers' eye movement data (from 200 m before tunnel entrance to 200 m inside tunnel entrance) under five predetermined vehicle speeds (40, 50, 60, 70 and 80 km/h) in the daytime and three predetermined vehicle speeds (40, 60 and 80 km/h) in the nighttime were recorded using the non-intrusive Dikablis Professional eye-tracking system. Pupil size, the average fixation duration time and the average number of fixation were analyzed and then the influence of the vehicle speed on these parameters was evaluated by means of IBM SPSS Statistics 20.0. The results for pupil size in daytime increased when approaching the tunnel entrance, while as for nighttime, pupil size decreased when approaching the tunnel entrance and then increased after entering the tunnel. The pupil size in daytime has a significant negative correlation with vehicle speed, while the pupil size in nighttime did not show a significant association with vehicle speed. Furthermore, the average fixation duration in daytime increased when entering the tunnel, and had a significant negative correlation with vehicle speed. Also, the average number of fixations in daytime decreased when entering the tunnel and has a significant negative correlation with vehicle speed. However, the average fixation duration and the average number of fixations in nighttime did not show any significant association with vehicle speed. Moreover, limitations and future directions of the study are discussed for the further investigation.

  18. Visual encoding and fixation target selection in free viewing: presaccadic brain potentials

    Directory of Open Access Journals (Sweden)

    Andrey R Nikolaev

    2013-06-01

    Full Text Available In scrutinizing a scene, the eyes alternate between fixations and saccades. During a fixation, two component processes can be distinguished: visual encoding and selection of the next fixation target. We aimed to distinguish the neural correlates of these processes in the electrical brain activity prior to a saccade onset. Participants viewed color photographs of natural scenes, in preparation for a change detection task. Then, for each participant and each scene we computed an image heat map, with temperature representing the duration and density of fixations. The temperature difference between the start and end points of saccades was taken as a measure of the expected task-relevance of the information concentrated in specific regions of a scene. Visual encoding was evaluated according to whether subsequent change was correctly detected. Saccades with larger temperature difference were more likely to be followed by correct detection than ones with smaller temperature differences. The amplitude of presaccadic activity over anterior brain areas was larger for correct detection than for detection failure. This difference was observed for short scrutinizing but not for long explorative saccades, suggesting that presaccadic activity reflects top-down saccade guidance. Thus, successful encoding requires local scanning of scene regions which are expected to be task-relevant. Next, we evaluated fixation target selection. Saccades moving up in temperature were preceded by presaccadic activity of higher amplitude than those moving down. This finding suggests that presaccadic activity reflects attention deployed to the following fixation location. Our findings illustrate how presaccadic activity can elucidate concurrent brain processes related to the immediate goal of planning the next saccade and the larger-scale goal of constructing a robust representation of the visual scene.

  19. The Added Value of Eye-tracking in Diagnosing Dyscalculia: A Case Study

    Directory of Open Access Journals (Sweden)

    Sietske eVan Viersen

    2013-10-01

    Full Text Available The present study compared eye movements and performance of a nine-year-old girl with Developmental Dyscalculia (DD on a series of number line tasks to those of a group of typically developing (TD children (n = 10, in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R2 and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to approximately 10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  20. The added value of eye-tracking in diagnosing dyscalculia: a case study.

    Science.gov (United States)

    van Viersen, Sietske; Slot, Esther M; Kroesbergen, Evelyn H; Van't Noordende, Jaccoline E; Leseman, Paul P M

    2013-01-01

    The present study compared eye movements and performance of a 9-year-old girl with Developmental Dyscalculia (DD) on a series of number line tasks to those of a group of typically developing (TD) children (n = 10), in order to answer the question whether eye-tracking data from number line estimation tasks can be a useful tool to discriminate between TD children and children with a number processing deficit. Quantitative results indicated that the child with dyscalculia performed worse on all symbolic number line tasks compared to the control group, indicated by a low linear fit (R (2)) and a low accuracy measured by mean percent absolute error. In contrast to the control group, her magnitude representations seemed to be better represented by a logarithmic than a linear fit. Furthermore, qualitative analyses on the data of the child with dyscalculia revealed more unidentifiable fixation patterns in the processing of multi-digit numbers and more dysfunctional estimation strategy use in one third of the estimation trials as opposed to ~10% in the control group. In line with her dyscalculia diagnosis, these results confirm the difficulties with spatially representing and manipulating numerosities on a number line, resulting in inflexible and inadequate estimation or processing strategies. It can be concluded from this case study that eye-tracking data can be used to discern different number processing and estimation strategies in TD children and children with a number processing deficit. Hence, eye-tracking data in combination with number line estimation tasks might be a valuable and promising addition to current diagnostic measures.

  1. An analysis of the suitability of a low-cost eye tracker for assessing the cognitive load of drivers.

    Science.gov (United States)

    Čegovnik, Tomaž; Stojmenova, Kristina; Jakus, Grega; Sodnik, Jaka

    2018-04-01

    This paper presents a driving simulator study in which we investigated whether the Eye Tribe eye tracker (ET) is capable of assessing changes in the cognitive load of drivers through oculography and pupillometry. In the study, participants were asked to drive a simulated vehicle and simultaneously perform a set of secondary tasks with different cognitive complexity levels. We measured changes in eye properties, such as the pupil size, blink rate and fixation time. We also performed a measurement with a Detection Response Task (DRT) to validate the results and to prove a steady increase of cognitive load with increasing secondary task difficulty. The results showed that the ET precisely recognizes an increasing pupil diameter with increasing secondary task difficulty. In addition, the ET shows increasing blink rates, decreasing fixation time and narrowing of the attention field with increasing secondary task difficulty. The results were validated with the DRT method and the secondary task performance. We conclude that the Eye Tribe ET is a suitable device for assessing a driver's cognitive load. Copyright © 2017 Elsevier Ltd. All rights reserved.

  2. Keeping Your Eye on the Rail: Gaze Behaviour of Horse Riders Approaching a Jump

    Science.gov (United States)

    Hall, Carol; Varley, Ian; Kay, Rachel; Crundall, David

    2014-01-01

    The gaze behaviour of riders during their approach to a jump was investigated using a mobile eye tracking device (ASL Mobile Eye). The timing, frequency and duration of fixations on the jump and the percentage of time when their point of gaze (POG) was located elsewhere were assessed. Fixations were identified when the POG remained on the jump for 100 ms or longer. The jumping skill of experienced but non-elite riders (n = 10) was assessed by means of a questionnaire. Their gaze behaviour was recorded as they completed a course of three identical jumps five times. The speed and timing of the approach was calculated. Gaze behaviour throughout the overall approach and during the last five strides before take-off was assessed following frame-by-frame analyses. Differences in relation to both round and jump number were found. Significantly longer was spent fixated on the jump during round 2, both during the overall approach and during the last five strides (pJump 1 was fixated on significantly earlier and more frequently than jump 2 or 3 (pjump 3 than with jump 1 (p = 0.01) but there was no difference in errors made between rounds. Although no significant correlations between gaze behaviour and skill scores were found, the riders who scored higher for jumping skill tended to fixate on the jump earlier (p = 0.07), when the horse was further from the jump (p = 0.09) and their first fixation on the jump was of a longer duration (p = 0.06). Trials with elite riders are now needed to further identify sport-specific visual skills and their relationship with performance. Visual training should be included in preparation for equestrian sports participation, the positive impact of which has been clearly demonstrated in other sports. PMID:24846055

  3. Comparing eye tracking with electrooculography for measuring individual sentence comprehension duration

    DEFF Research Database (Denmark)

    Müller, Jana Annina; Wendt, Dorothea; Kollmeier, Birger

    2016-01-01

    The aim of this study was to validate a procedure for performing the audio-visual paradigm introduced by Wendt et al. (2015) with reduced practical challenges. The original paradigm records eye fixations using an eye tracker and calculates the duration of sentence comprehension based on a bootstrap...... procedure. In order to reduce practical challenges, we first reduced the measurement time by evaluating a smaller measurement set with fewer trials. The results of 16 listeners showed effects comparable to those obtained when testing the original full measurement set on a different collective of listeners...

  4. Impaired exploratory eye movements in children with Asperger's syndrome.

    Science.gov (United States)

    Ohya, Takashi; Morita, Kiichiro; Yamashita, Yushiro; Egami, Chiyomi; Ishii, Youhei; Nagamitsu, Shinichiro; Matsuishi, Toyojiro

    2014-03-01

    Previous eye-tracking studies using an eye mark recorder have reported that disturbances in exploratory eye movements in adult schizophrenic patients are associated with social functioning. The current study sought to determine whether exploratory eye-movement disturbances are present in children with Asperger's syndrome (AS) compared with typically developing (TD) children. MATERIALS/PARTICIPANTS: The participants were 23 children with AS and 23 age-matched TD children. We measured exploratory eye movements using an EMR-8B eye mark recorder and an exploratory eye movement-measuring device. Eye movements were recorded while participants freely observed a geometric figure (free viewing task), and while they complied with the instructions of an experimenter (repeat-comparison task). We assessed eye fixation points (EFPs) and total eye scanning length (TESL) in all tasks, and measured the responsive search score (RSS) in the repeat-comparison task. In the free viewing task, children with AS exhibited significantly shorter TESL compared with TD children. In the repeat-comparison task, children with AS exhibited significantly lower RSS. Autism Spectrum Screening Questionnaire scores were negatively correlated with both EFP and TESL, but not RSS. The current results revealed that children with AS exhibited dysfunction in exploratory eye movements. Thus, assessing exploratory eye movements in a repeat-comparison task may be useful for detecting social impairment among children with AS. Copyright © 2013 The Japanese Society of Child Neurology. Published by Elsevier B.V. All rights reserved.

  5. New evidence for strategic differences between static and dynamic search tasks: An individual observer analysis of eye movements

    Directory of Open Access Journals (Sweden)

    Christopher eDickinson

    2013-01-01

    Full Text Available Two experiments are reported that further explore the processes underlying dynamic search. In Experiment 1, observers’ oculomotor behavior was monitored while they searched for a randomly oriented T among oriented L distractors under static and dynamic viewing conditions. Despite similar search slopes, eye movements were less frequent and more spatially constrained under dynamic viewing relative to static, with misses also increasing more with target eccentricity in the dynamic condition. These patterns suggest that dynamic search involves a form of sit-and-wait strategy in which search is restricted to a small group of items surrounding fixation. To evaluate this interpretation, we developed a computational model of a sit-and-wait process hypothesized to underlie dynamic search. In Experiment 2 we tested this model by varying fixation position in the display and found that display positions optimized for a sit-and-wait strategy resulted in higher d' values relative to a less optimal location. We conclude that different strategies, and therefore underlying processes, are used to search static and dynamic displays.

  6. Effect of driving experience on anticipatory look-ahead fixations in real curve driving.

    Science.gov (United States)

    Lehtonen, Esko; Lappi, Otto; Koirikivi, Iivo; Summala, Heikki

    2014-09-01

    Anticipatory skills are a potential factor for novice drivers' curve accidents. Behavioural data show that steering and speed regulation are affected by forward planning of the trajectory. When approaching a curve, the relevant visual information for online steering control and for planning is located at different eccentricities, creating a need to disengage the gaze from the guidance of steering to anticipatory look-ahead fixations over curves. With experience, peripheral vision can be increasingly used in the visual guidance of steering. This could leave experienced drivers more gaze time to invest on look-ahead fixations over curves, facilitating the trajectory planning. Eighteen drivers (nine novices, nine experienced) drove an instrumented vehicle on a rural road four times in both directions. Their eye movements were analyzed in six curves. The trajectory of the car was modelled and divided to approach, entry and exit phases. Experienced drivers spent less time on the road-ahead and more time on the look-ahead fixations over the curves. Look-ahead fixations were also more common in the approach than in the entry phase of the curve. The results suggest that with experience drivers allocate greater part of their visual attention to trajectory planning. Copyright © 2014 Elsevier Ltd. All rights reserved.

  7. [Comparison of external fixation with or without limited internal fixation for open knee fractures].

    Science.gov (United States)

    Li, K N; Lan, H; He, Z Y; Wang, X J; Yuan, J; Zhao, P; Mu, J S

    2018-03-01

    Objective: To explore the characteristics and methods of different fixation methods and prevention of open knee joint fracture. Methods: The data of 86 cases of open knee joint fracture admitted from January 2002 to December 2015 in Department of Orthopaedics, Affiliated Hospital of Chengdu University were analyzed retrospectively.There were 65 males and 21 females aged of 38.6 years. There were 38 cases treated with trans articular external fixation alone, 48 cases were in the trans articular external fixation plus auxiliary limited internal fixation group. All the patients were treated according to the same three stages except for different fixation methods. Observation of external fixation and fracture fixation, fracture healing, wound healing and treatment, treatment and related factors of infection control and knee function recovery. χ(2) test was used to analyze data. Results: Eleven patients had primary wound healing, accounting for 12.8%. Seventy-five patients had two wounds healed, accounting for 87.2%. Only 38 cases of trans articular external fixator group had 31 cases of articular surface reduction, accounting for 81.6%; Five cases of trans articular external fixator assisted limited internal fixation group had 5 cases of poor reduction, accounting for 10.4%; There was significant difference between the two groups (χ(2)=44.132, P external fixation group, a total of 23 cases of patients with infection, accounted for 60.5% of external fixation group; trans articular external fixation assisted limited internal fixation group there were 30 cases of patients with infection, accounting for the assistance of external fixator and limited internal fixation group 62.5%; There was significant difference between the two groups(χ(2)=0.035, P >0.05). Five cases of fracture nonunion cases of serious infection, patients voluntarily underwent amputation. The Lysholm Knee Scale: In the external fixation group, 23 cases were less than 50 points, accounting for 60

  8. Biological nitrogen fixation: rates, patterns and ecological controls in terrestrial ecosystems

    Science.gov (United States)

    Vitousek, Peter M.; Menge, Duncan N.L.; Reed, Sasha C.; Cleveland, Cory C.

    2013-01-01

    New techniques have identified a wide range of organisms with the capacity to carry out biological nitrogen fixation (BNF)—greatly expanding our appreciation of the diversity and ubiquity of N fixers—but our understanding of the rates and controls of BNF at ecosystem and global scales has not advanced at the same pace. Nevertheless, determining rates and controls of BNF is crucial to placing anthropogenic changes to the N cycle in context, and to understanding, predicting and managing many aspects of global environmental change. Here, we estimate terrestrial BNF for a pre-industrial world by combining information on N fluxes with 15N relative abundance data for terrestrial ecosystems. Our estimate is that pre-industrial N fixation was 58 (range of 40–100) Tg N fixed yr−1; adding conservative assumptions for geological N reduces our best estimate to 44 Tg N yr−1. This approach yields substantially lower estimates than most recent calculations; it suggests that the magnitude of human alternation of the N cycle is substantially larger than has been assumed.

  9. Pigment dispersion syndrome and pigmentary glaucoma after secondary sulcus transscleral fixation of single-piece foldable posterior chamber intraocular lenses in Chinese aphakic patients.

    Science.gov (United States)

    Tong, Nianting; Liu, Fuling; Zhang, Ting; Wang, Liangyu; Zhou, Zhanyu; Gong, Huimin; Yuan, Fuxiang

    2017-05-01

    To describe secondary pigment dispersion syndrome (PDS) and pigmentary glaucoma after secondary sulcus transscleral fixation of 1-piece hydrophobic acrylic foldable posterior chamber intraocular lenses (PC IOLs) in aphakic patients in a Chinese population. Department of Ophthalmology, Qingdao Municipal Hospital, Qingdao, China. Retrospective case series. This chart review included eyes that had secondary sulcus transscleral fixation of a 1-piece hydrophobic acrylic foldable PC IOL (Tecnis ZCB00) between March 2011 and March 2014. The patients' demographic data, clinical data, postoperative complications, intervals between initial surgery and the onset of PDS, pigmentary glaucoma occurrences, and findings on slitlamp biomicroscopy, gonioscopy, and ultrasound biomicroscopy (UBM) were recorded. The study comprised 23 consecutive eyes of 21 patients. Seventeen eyes of 16 patients were diagnosed with PDS, and 7 eyes of 6 patients were diagnosed with pigmentary glaucoma. The slitlamp examination and UBM showed that the location between the IOL optic and the posterior surface of the iris was very close. Slitlamp examination of the anterior chamber angle using a gonioscope showed dense pigment deposition on the IOL surfaces. A reverse pupillary block was found in 10 eyes of 9 patients. Other postoperative complications included intraocular hemorrhage, pupillary capture of the IOL optic, IOL tilt, IOL decentration, IOL dislocation, and suture erosion. The 1-piece hydrophobic acrylic foldable PC IOL was not suitable for sulcus transscleral fixation because of a high incidence of PDS and pigmentary glaucoma after surgery in a Chinese population. Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  10. Comparison of two-staged ORIF and limited internal fixation with external fixator for closed tibial plafond fractures.

    Science.gov (United States)

    Wang, Cheng; Li, Ying; Huang, Lei; Wang, Manyi

    2010-10-01

    To compare the results of two-staged open reduction and internal fixation (ORIF) and limited internal fixation with external fixator (LIFEF) for closed tibial plafond fractures. From January 2005 to June 2007, 56 patients with closed type B3 or C Pilon fractures were randomly allocated into groups I and II. Two-staged ORIF was performed in group I and LIFEF in group II. The outcome measures included bone union, nonunion, malunion, pin-tract infection, wound infection, osteomyelitis, ankle joint function, etc. These postoperative data were analyzed with Statistical Package for Social Sciences (SPSS) 13.0. Incidence of superficial soft tissue infection (involved in wound infection or pin-tract infection) in group I was lower than that in group II (P delayed union, and arthritis symptoms, with no statistical significance. Both groups resulted similar ankle joint function. Logistic regression analysis indicated that smoking and fracture pattern were the two factors significantly influencing the final outcomes. In the treatment of closed tibial plafond fractures, both two-staged ORIF and LIFEF offer similar results. Patients undergo LIFEF carry significantly greater radiation exposure and higher superficial soft tissue infection rate (usually occurs on pin tract and does not affect the final outcomes).

  11. Brand Medications and Medicare Part D: How Eye Care Providers' Prescribing Patterns Influence Costs.

    Science.gov (United States)

    Newman-Casey, Paula Anne; Woodward, Maria A; Niziol, Leslie M; Lee, Paul P; De Lott, Lindsey B

    2018-03-01

    To quantify costs of eye care providers' Medicare Part D prescribing patterns for ophthalmic medications and to estimate the potential savings of generic or therapeutic drug substitutions and price negotiation. Retrospective cross-sectional study. Eye care providers prescribing medications through Medicare Part D in 2013. Medicare Part D 2013 prescriber public use file and summary file were used to calculate medication costs by physician specialty and drug. Savings from generic or therapeutic drug substitutions were estimated for brand drugs. The potential savings from price negotiation was estimated using drug prices negotiated by the United States Veterans Administration (USVA). Total cost of brand and generic medications prescribed by eye care providers. Eye care providers accounted for $2.4 billion in total Medicare part D prescription drug costs and generated the highest percentage of brand name medication claims compared with all other providers. Brand medications accounted for a significantly higher proportion of monthly supplies by volume, and therefore, also by total cost for eye care providers compared with all other providers (38% vs. 23% by volume, P total cost, P total cost attributable to eye care providers is driven by glaucoma medications, accounting for $1.2 billion (54% of total cost; 72% of total volume). The second costliest category, dry eye medications, was attributable mostly to a single medication, cyclosporine ophthalmic emulsion (Restasis, Allergan, Irvine, CA), which has no generic alternative, accounting for $371 million (17% of total cost; 4% of total volume). If generic medications were substituted for brand medications when available, $148 million would be saved (7% savings); if generic and therapeutic substitutions were made, $882 million would be saved (42% savings). If Medicare negotiated the prices for ophthalmic medications at USVA rates, $1.09 billion would be saved (53% savings). Eye care providers prescribe more brand

  12. Familial transmission of a body-related attentional bias - An eye-tracking study in a nonclinical sample of female adolescents and their mothers.

    Directory of Open Access Journals (Sweden)

    Anika Bauer

    Full Text Available Previous research indicates that body image disturbance is transmitted from mother to daughter via modeling of maternal body-related behaviors and attitudes (indirect transmission and via maternal body-related feedback (direct transmission. So far, the transmission of body-related attentional biases, which according to cognitive-behavioral theories play a prominent role in the development and maintenance of eating disorders, has not been analyzed. The current eye-tracking study applied the concepts of direct and indirect transmission to body-related attentional biases by examining body-related viewing patterns on self- and other-pictures within mother-daughter dyads.Eye movements of N = 82 participants (n = 41 healthy female adolescents, mean age 15.82 years, SD = 1.80, and their mothers, mean age 47.78 years, SD = 4.52 were recorded while looking at whole-body pictures of themselves and a control peer. Based on fixations on self-defined attractive and unattractive body areas, visual attention bias scores were calculated for mothers and daughters, representing the pattern of body-related attention allocation. Based on mothers' fixations on their own daughter's and the adolescent peer's body, a second visual attention bias score was calculated, reflecting the mothers' viewing pattern on their own daughter.Analysis of variance revealed an attentional bias for self-defined unattractive body areas in adolescents. The girls' visual attention bias score correlated significantly with their mothers' bias score, indicating indirect transmission, and with their mothers' second bias score, indicating direct transmission. Moreover, the girls' bias score correlated significantly with negative body-related feedback from their mothers.Female adolescents show a deficit-oriented attentional bias for one's own and a peer's body. The correlated body-related attention patterns imply that attentional biases might be transmitted directly and indirectly from mothers

  13. Lens artifacts in human fetal eyes - the challenge of interpreting the histomorphology of human fetal lenses.

    Science.gov (United States)

    Herwig, Martina C; Müller, Annette M; Klarmann-Schulz, Ute; Holz, Frank G; Loeffler, Karin U

    2014-01-01

    Evaluation of the lens, including cataractous changes, is often of paramount importance in the classification of fetal syndromes or forensic questions. On histology, the crystalline lens is - especially in fetal and infant eyes - an organ susceptible to numerous artifacts. Thus, the aim of our study was to study various factors (including fixatives) that might have an impact on lens histomorphology. Twenty eyes from ten fetuses (formalin fixation: n = 10, glutaraldehyde fixation: n = 10), matched for gestational age and abortion (spontaneous vs. induced), were investigated macroscopically and by light microscopy. Sections were stained with routine hematoxylin & eosin (H&E), and periodic acid schiff (PAS). The age of the fetal eyes ranged from 15 to 36 weeks of gestation. Lens artifacts were analyzed and compared to fetal and adult lenses with definitive cataractous changes. In addition, 34 eyes from 27 fetuses with trisomy 21 were investigated for lens changes. All lenses showed artifacts of varying extent, in particular globules, vacuoles, clefts, anterior/posterior capsular separation, subcapsular proteinaceous material, fragmentation of the lens capsule/epithelium, and a posterior umbilication. Glutaraldehyde-fixed lenses displayed less artifacts compared to those fixed in formalin. Slight differences in the appearance of artifacts were found dependent on the fixative (formaldehyde vs glutaraldehyde) and the kind of abortion (iatrogenous vs spontaneous). The gestational age did not have a significant influence on the type and extent of lens artifacts. The lenses from fetuses with trisomy 21 displayed similar lens artifacts with no specific findings. Alterations in fetal lens morphology are extremely frequent and variable. These artifacts have to be carefully taken into account when interpreting post-mortem findings. Thus, the postmortem diagnosis of a fetal cataract should be made with great caution, and should include, in adherence to our proposed

  14. The Effects of Campus Bump on Drivers’ Fixation Dispersion and Speed Reduction

    Directory of Open Access Journals (Sweden)

    Qian Xu

    2015-01-01

    Full Text Available To evaluate the effects of campus speed bumps on drivers’ speed and fixation distribution, a quasinaturalistic driving test was conducted on a Chinese campus. Seven randomly selected drivers, wearing the Dikablis eye tracking devices, were required to drive an OPEL SUV passing the speed bumps. The area close to the bump was divided into ten subsegments (15 m for each one. The degree of fixation dispersion within each subsegment was defined as the distance from each subcenter to the whole fixation center. All traffic data were recorded using mounted camera, and the trajectories were extracted in Matlab. The speed and trajectory data was divided into two groups: the before group for bump-free case and the after group for a 5 cm bump case. The observational before-after analysis shows statistical significance between the two cases. The individual vehicular speed analysis reveals that bump reduces nearly 60% of vehicles’ speeds to a certain extent within the distance from 30 m upstream to 15 m downstream. The drivers’ fixation points begin to disperse 30–45 m before they see the bump, and it falls back to normal level 15–30 m downstream of the bump. These findings will help engineers install speed bumps at the most appropriate locations.

  15. Eye and Hand Movements during Reconstruction of Spatial Memory

    Directory of Open Access Journals (Sweden)

    Melanie Rose Burke

    2012-05-01

    Full Text Available Recent behavioural and biological evidence indicates common mechanisms serving working memory and attention (eg, Awh et al 2006, Trends in Cognitive Sciences 10, 124–130. This study explored the role of spatial attention and visual search in an adapted Corsi spatial memory task. Eye movements and touch responses were recorded from participants who recalled locations (signalled by colour or shape change from an array presented either simultaneously or sequentially. The time delay between target presentation and recall (0, 5, or 10s and the number of locations to be remembered (2–5 were also manipulated. Analysis of the response phase revealed subjects were less accurate (touch data and fixated longer (eye data when responding to sequentially presented targets. Fixation duration was also influenced by whether spatial location was initially signalled by colour or shape change. We conclude that attention and temporal delays during retention of a target play a minor role in motor behaviour during a corsi spatial memory task. In contrast, the type of memory required (ie, location and/or memory and number of items plays a key role on subject performance and behaviour.

  16. Prediction of human eye fixations using symmetry

    NARCIS (Netherlands)

    Kootstra, Gert; Schomaker, Lambert

    2009-01-01

    Humans are very sensitive to symmetry in visual patterns. Reaction time experiments show that symmetry is detected and recognized very rapidly. This suggests that symmetry is a highly salient feature. Existing computational models of saliency, however, have mainly focused on contrast as a measure of

  17. Outcomes and Complications of Scleral-Fixated Intraocular Lens Combined with Ahmed Tube Surgery

    Directory of Open Access Journals (Sweden)

    Nikhel Sachdev

    2018-01-01

    Full Text Available Background. To evaluate the outcome and complications of transscleral suture-fixated posterior chamber intraocular lens (PCIOL implantation combined with Ahmed glaucoma valve (AGV surgery in Asian eyes. Design. This was a retrospective study that included 22 eyes from 22 participants. The surgeries were performed at Singapore’s National University Hospital. Participants underwent an Ahmed tube surgery, together with transscleral suture-fixated posterior chamber intraocular lens. Main Outcome Measures. Complete success was defined as 6 ≤ intraocular pressure (IOP ≤ 21 mmHg without medications at the last follow-up visit, with no reoperation required and no progression to no perception of light (NPL. Results. At the last follow-up, there was a significant reduction in mean IOP (22.4 ± 6.5 mmHg versus 13.9 ± 3.9 mmHg; p<0.001 and mean number of intraocular pressure-lowering medications (2.45 ± 1.30 versus 0.05 ± 0.21; p<0.001. There was no significant change in visual acuity [1.43 ± 1.21 (LogMAR versus 1.09 ± 1.31 (p=0.204]. Sixteen eyes (72.7% achieved complete success. The 3 commonest complications were bullous keratopathy, choroidal detachment, and displacement of intraocular lens. Conclusion and Relevance. This technique showed good success for intraocular pressure control and vision preservation. Postoperative complications were relatively common although most were self-limiting. Patients at increased risk of trabeculectomy failure may be suitable for this procedure.

  18. Kinetics of transfemoral amputees with osseointegrated fixation performing common activities of daily living.

    Science.gov (United States)

    Lee, Winson C C; Frossard, Laurent A; Hagberg, Kerstin; Haggstrom, Eva; Brånemark, Rickard; Evans, John H; Pearcy, Mark J

    2007-07-01

    Direct anchorage of a lower-limb prosthesis to the bone through an implanted fixation (osseointegration) has been suggested as an excellent alternative for amputees experiencing complications from use of a conventional socket-type prosthesis. However, an attempt needs to be made to optimize the mechanical design of the fixation and refine the rehabilitation program. Understanding the load applied on the fixation is a crucial step towards this goal. The load applied on the osseointegrated fixation of nine transfemoral amputees was measured using a load transducer, when the amputees performed activities which included straight-line level walking, ascending and descending stairs and a ramp as well as walking around a circle. Force and moment patterns along each gait cycle, magnitudes and time of occurrence of the local extrema of the load, as well as impulses were analysed. Managing a ramp and stairs, and walking around a circle did not produce a significant increase (P>0.05) in load compared to straight-line level walking. The patterns of the moment about the medio-lateral axis were different among the six activities which may reflect the different strategies used in controlling the prosthetic knee joint. This study increases the understanding of biomechanics of bone-anchored osseointegrated prostheses. The loading data provided will be useful in designing the osseointegrated fixation to increase the fatigue life and to refine the rehabilitation protocol.

  19. Viewing-position effects in the Stroop task: Initial fixation position modulates Stroop effects in fully colored words.

    Science.gov (United States)

    Perret, Patrick; Ducrot, Stéphanie

    2010-08-01

    In two experiments that we conducted with adult (Experiment 1) and child (Experiment 2) participants, we experimentally controlled the eyes' first fixation in the word using a variable viewing-position technique in a classical all-letter-coloring Stroop procedure. We explored the impact of initial-fixation position (optimal viewing position [OVP] vs. end of the word) on the magnitude of Stroop effects (both interference and facilitation). The results showed that both interference and facilitation effects were reduced when the first fixation was located at the end of the word rather than at the OVP. These data make a new contribution to the study of the role of low-level processes in Stroop effects and add support to the growing body of research indicating that oculomotor processes can act as moderators of cognitive processes in the determination of Stroop effects.

  20. REVISION ANKLE SYNDESMOSIS FIXATION - FUNCTIONAL OUTCOME AFTER TIGHTROPE ® FIXATION

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    Sendhilvelan Rajagopalan

    2016-07-01

    Full Text Available BACKGROUND Syndesmotic disruptions are often seen in ankle fractures. Malreduction of these fractures can result in arthritis and instability. A proportion of these patients with malreduction require revision fixation. This study presents the results of revision fixation in such patients, using the Ankle TightRope ® (Arthrex system. METHODS Between January 2000 to December 2009, 124 patients who underwent ankle fracture fixations with syndesmotic stabilisation were analysed. Out of 124 patients, 8 patients were diagnosed with failure of primary stabilisation (based on radiological and clinical criteria and subjected to revision fixation using the Ankle TightRope ® (Arthrex system. Followup was done at periodic time intervals of 3, 6 and 12 months. Both clinical and radiological assessment was performed. Complications and duration of hospital stay was recorded. Functional evaluation was performed using the American Orthopaedic Foot and Ankle Society (AOFAS scoring system. RESULTS Five patients had good results, one satisfactory and two had poor outcomes. CONCLUSIONS Ankle TightRope ® fixation is an alternative method of stabilisation in patients who require revision syndesmosis fixation. Further studies are required to evaluate this method of revision stabilisation as compared to screws.

  1. Efference copy failure during smooth pursuit eye movements in schizophrenia.

    Science.gov (United States)

    Spering, Miriam; Dias, Elisa C; Sanchez, Jamie L; Schütz, Alexander C; Javitt, Daniel C

    2013-07-17

    Abnormal smooth pursuit eye movements in patients with schizophrenia are often considered a consequence of impaired motion perception. Here we used a novel motion prediction task to assess the effects of abnormal pursuit on perception in human patients. Schizophrenia patients (n = 15) and healthy controls (n = 16) judged whether a briefly presented moving target ("ball") would hit/miss a stationary vertical line segment ("goal"). To relate prediction performance and pursuit directly, we manipulated eye movements: in half of the trials, observers smoothly tracked the ball; in the other half, they fixated on the goal. Strict quality criteria ensured that pursuit was initiated and that fixation was maintained. Controls were significantly better in trajectory prediction during pursuit than during fixation, their performance increased with presentation duration, and their pursuit gain and perceptual judgments were correlated. Such perceptual benefits during pursuit may be due to the use of extraretinal motion information estimated from an efference copy signal. With an overall lower performance in pursuit and perception, patients showed no such pursuit advantage and no correlation between pursuit gain and perception. Although patients' pursuit showed normal improvement with longer duration, their prediction performance failed to benefit from duration increases. This dissociation indicates relatively intact early visual motion processing, but a failure to use efference copy information. Impaired efference function in the sensory system may represent a general deficit in schizophrenia and thus contribute to symptoms and functional outcome impairments associated with the disorder.

  2. Spatio-temporal dynamics of the white-eye square superlattice pattern in dielectric barrier discharge

    International Nuclear Information System (INIS)

    Wei, Lingyan; Dong, Lifang; Feng, Jianyu; Liu, Weibo; Fan, Weili; Pan, Yuyang

    2016-01-01

    We report on the first investigation of the white-eye square superlattice pattern (WESSP) in a dielectric barrier discharge system. The evolution of patterns with increasing voltage is given. A phase diagram of WESSP as functions of gas pressure p and argon concentration φ is presented. The spatio-temporal dynamics of the WESSP is studied by using an intensified charge-coupled device camera and photomultipliers. Results show that the WESSP consists of four different transient sublattices, whose discharge sequence is small spots—spots on the line—halos—central spots in each half voltage cycle. The discharge moment and position of each sublattice are dependent upon the field of the wall charges produced by all sublattices discharged previously. (paper)

  3. Opacification of the C-flex 570C intraocular lens after sulcus fixation.

    Science.gov (United States)

    Daigle, Patrick; Carbonneau, Marjorie

    2017-09-08

    To report a case of diffuse intraocular lens (IOL) opacification in a patient who started complaining of blurred vision in his left eye over the course of three years after having phacoemulsification surgery combined with capsular bag fixation of a C-flex 570C IOL. The IOL had been repositioned in the ciliary sulcus following its subluxation. An IOL exchange was performed, and the explanted IOL was sent for histopathological analysis. Scanning electron microscopy identified multiple crystalline-like deposits on both sides of the IOL. The optic was more extensively involved than the haptics. Energy-dispersive X-ray spectroscopy confirmed the predominance of calcium within the deposits. The breakdown of the blood-aqueous barrier seems to be a key component of this calcification process. Ciliary sulcus fixation is not a suitable option for C-flex 570C IOLs.

  4. Glued intrascleral fixation of posterior chamber intraocular lens in children.

    Science.gov (United States)

    Kumar, Dhivya Ashok; Agarwal, Amar; Prakash, Dimple; Prakash, Gaurav; Jacob, Soosan; Agarwal, Athiya

    2012-04-01

    To evaluate the short-term results of glued intrascleral fixation of posterior chamber intraocular lens (glued IOL) in children without adequate capsular support. Noncomparative retrospective observational case series. Institutional practice. Forty-one eyes of 33 children who underwent glued IOL implantation were retrospectively evaluated. The indications were postsurgical aphakia, subluxated cataract, ectopia lentis, traumatic subluxation, and decentered IOL. Visual acuity (VA), endothelial cell changes, intraoperative and postoperative complications. The mean age at the time of glued IOL was 10.7±3.6 years (range 5-15). The mean duration of follow-up after surgery was 17.5±8.5 months (range 12-36). The mean postoperative best spectacle-corrected visual acuity (BCVA in decimal equivalent) was 0.43±0.33 and there was significant change noted (P20/60 BCVA was obtained in 17.1% and 46.3% of eyes respectively. BCVA improvement more than 1 line was seen in 22 eyes (53.6%). The mean postoperative refraction was myopic (-1.19±0.7 diopters [D]) in 19 eyes and hyperopic (+1.02±0.7 D) in 22 eyes. The mean endothelial loss was 4.13% (range 1.3%-5.94%). The 3 causes of reduced BCVA were the preexisting corneal, retinal pathology, and amblyopia. Postoperative complications included optic capture in 1 eye (2.4%), macular edema in 2 eyes (4.8%), and clinical decentration in 2 eyes (4.8%). There was no postoperative retinal detachment, IOL dislocation, endophthalmitis, or glaucoma. Short-term results in children after glued IOL were favorable, with a low rate of complications. However, regular follow-ups are required since long-term risks are unknown. Copyright © 2012 Elsevier Inc. All rights reserved.

  5. Eye movements as an index of pathologist visual expertise: a pilot study.

    Directory of Open Access Journals (Sweden)

    Tad T Brunyé

    Full Text Available A pilot study examined the extent to which eye movements occurring during interpretation of digitized breast biopsy whole slide images (WSI can distinguish novice interpreters from experts, informing assessments of competency progression during training and across the physician-learning continuum. A pathologist with fellowship training in breast pathology interpreted digital WSI of breast tissue and marked the region of highest diagnostic relevance (dROI. These same images were then evaluated using computer vision techniques to identify visually salient regions of interest (vROI without diagnostic relevance. A non-invasive eye tracking system recorded pathologists' (N = 7 visual behavior during image interpretation, and we measured differential viewing of vROIs versus dROIs according to their level of expertise. Pathologists with relatively low expertise in interpreting breast pathology were more likely to fixate on, and subsequently return to, diagnostically irrelevant vROIs relative to experts. Repeatedly fixating on the distracting vROI showed limited value in predicting diagnostic failure. These preliminary results suggest that eye movements occurring during digital slide interpretation can characterize expertise development by demonstrating differential attraction to diagnostically relevant versus visually distracting image regions. These results carry both theoretical implications and potential for monitoring and evaluating student progress and providing automated feedback and scanning guidance in educational settings.

  6. Preliminary experience with biodegradable implants for fracture fixation

    Directory of Open Access Journals (Sweden)

    Dhillon Mandeep

    2008-01-01

    Full Text Available Background: Biodegradable implants were designed to overcome the disadvantages of metal-based internal fixation devices. Although they have been in use for four decades internationally, many surgeons in India continue to be skeptical about the mechanical strength of biodegradable implants, hence this study. Materials and Methods: A prospective study was done to assess the feasibility and surgeon confidence level with biodegradable implants over a 12-month period in an Indian hospital. Fifteen fractures (intra-articular, metaphyseal or small bone fractures were fixed with biodegradable implants. The surgeries were randomly scheduled so that different surgeons with different levels of experience could use the implants for fixation. Results: Three fractures (one humeral condyle, two capitulum, were supplemented by additional K-wires fixation. Trans-articular fixator was applied in two distal radius and two pilon fractures where bio-pins alone were used. All fractures united, but in two cases the fracture displaced partially during the healing phase; one fibula due to early walking, and one radius was deemed unstable even after bio-pin and external fixator. Conclusions: Biodegradable -implants are excellent for carefully selected cases of intra-articular fractures and some small bone fractures. However, limitations for use in long bone fractures persist and no great advantage is gained if a "hybrid" composite is employed. The mechanical properties of biopins and screws in isolation are perceived to be inferior to those of conventional metal implants, leading to low confidence levels regarding the stability of reduced fractures; these implants should be used predominantly in fracture patterns in which internal fixation is subjected to minimal stress.

  7. Poly(ADP-ribose) Glycohydrolase and Poly(ADP-ribose)-interacting Protein Hrp38 Regulate Pattern Formation during Drosophila Eye Development

    Science.gov (United States)

    Ji, Yingbiao; Jarnik, Michael; Tulin, Alexei V.

    2013-01-01

    Drosophila Hrp38, a homolog of human hnRNP A1, has been shown to regulate splicing, but its function can be modified by poly(ADP-ribosyl)ation. Notwithstanding such findings, our understanding of the roles of poly(ADP-ribosyl)ated Hrp38 on development is limited. Here, we have demonstrated that Hrp38 is essential for fly eye development based on a rough-eye phenotype with disorganized ommatidia observed in adult escapers of the hrp38 mutant. We also observed that Poly(ADP-ribose) Glycohydrolase (Parg) loss-of-function, which caused increased Hrp38 poly(ADP-ribosyl)ation, also resulted in the rough-eye phenotype with disrupted ommatidial lattice and reduced number of photoreceptor cells. In addition, ectopic expression of DE-cadherin, which is required for retinal morphogenesis, fully rescued the rough-eye phenotype of the hrp38 mutant. Similarly, Parg mutant eye clones had decreased expression level of DE-cadherin with orientation defects, which is reminiscent of DE-cadherin mutant eye phenotype. Therefore, our results suggest that Hrp38 poly(ADP-ribosyl)ation controls eye pattern formation via regulation of DE-cadherin expression, a finding which has implications for understanding the pathogenic mechanisms of Hrp38-related Fragile X syndrome and PARP1-related retinal degeneration diseases. PMID:23711619

  8. Eye tracking social preferences

    NARCIS (Netherlands)

    Jiang, Ting; Potters, Jan; Funaki, Yukihiko

    We hypothesize that if people are motivated by a particular social preference, then choosing in accordance with this preference will lead to an identifiable pattern of eye movements. We track eye movements while subjects make choices in simple three-person distribution experiments. We characterize

  9. Taxonomic identity determines N2 fixation by canopy trees across lowland tropical forests.

    Science.gov (United States)

    Wurzburger, Nina; Hedin, Lars O

    2016-01-01

    Legumes capable of fixing atmospheric N2 are abundant and diverse in many tropical forests, but the factors determining ecological patterns in fixation are unresolved. A long-standing idea is that fixation depends on soil nutrients (N, P or Mo), but recent evidence shows that fixation may also differ among N2-fixing species. We sampled canopy-height trees across five species and one species group of N2-fixers along a landscape P gradient, and manipulated P and Mo to seedlings in a shadehouse. Our results identify taxonomy as the major determinant of fixation, with P (and possibly Mo) only influencing fixation following tree-fall disturbances. While 44% of trees did not fix N2, other trees fixed at high rates, with two species functioning as superfixers across the landscape. Our results raise the possibility that fixation is determined by biodiversity, evolutionary history and species-specific traits (tree growth rate, canopy stature and response to disturbance) in the tropical biome. © 2015 John Wiley & Sons Ltd/CNRS.

  10. Evaluation of the syndesmotic-only fixation for Weber-C ankle fractures with syndesmotic injury.

    Science.gov (United States)

    Mohammed, R; Syed, S; Metikala, S; Ali, Sa

    2011-09-01

    With the length of the fibula restored and the syndesmosis reduced anatomically, internal fixation using a plating device may not be necessary for supra-syndesmotic fibular fractures combined with diastasis of inferior tibio-fibular joint. A retrospective observational study was performed in patients who had this injury pattern treated with syndesmosis-only fixation. 12 patients who had Weber type-C injury pattern were treated with syndesmosis only fixation. The treatment plan was followed only if the fibular length could be restored and if the syndesmosis could be anatomically reduced. Through a percutaneous or mini-open reduction and clamp stabilization of the syndesmosis, all but one patient had a single tricortical screw fixation across the syndesmosis. Patients were kept non-weight-bearing for 6 weeks, followed by screw removal at an average of 8 weeks. Outcomes were assessed using an objective ankle scoring system (Olerud and Molander scale) and by radiographic assessment of the ankle mortise. At a mean follow-up of 13 months, the functional outcome score was 75. Excellent to good outcomes were noted in 83% of the patients. Ankle mortise was reduced in all cases, and all but one fibular fracture united without loss of fixation. Six patients had more than one malleolar injury, needing either screw or anchor fixations. One patient had late diastasis after removal of the syndesmotic screw and underwent revision surgery with bone grafting of the fibula. This was probably due to early screw removal, before union of the fibular fracture had occurred. We recommend syndesmosis-only fixation as an effective treatment option for a combination of syndesmosis disruption and Weber type-C lateral malleolar fractures.

  11. [Computer-assisted measurement of ocular misalignment in infants and young children using the digital Purkinje reflection pattern procedure].

    Science.gov (United States)

    Barry, J C; Effert, R; Kaupp, A; Kleine, M; Reim, M

    1994-02-01

    A digital image recording and processing system is presented that allows a quick diagnosis of microstrabismus in non-cooperative children. It is thus particularly suited for screening purposes. The Purkinje Reflection Pattern Evaluation (RPE) method is used: three small flashes are used to produce the desired Purkinje images. Two horizontal rows of the three 1st Purkinje images (anterior corneal reflections) and of the three 4th Purkinje images (posterior crystalline lens reflections) stemming from the three light sources form the characteristic Purkinje image reflection pattern. Each eye's position is calculated from the shift between the upper and lower rows of reflections by means of two simple formulae. From the angles obtained in binocular fixation and monocular fixation the manifest angle of strabismus corresponding to the angle measured in the simultaneous prism-and-cover test is computed. The measurement is performed at a fixation distance of 50 cm under natural viewing conditions. To obtain a picture one only has to get the child's attention for a short moment. The primary position is triggered with the fixation light, which is operated by a switch. The digital image recording is done with a hand-held device comprising two miniaturized video cameras, three photo flashes and a fixation light that is operated manually. An IBM-compatible PC equipped with a hard disk and two frame grabbers was adapted for the storage and processing of the pictures. The pictures are evaluated interactively in a few minutes on the workstation's monitor immediately after the measurement. To this end specially designed menu-driven software was implemented. Examples of the measuring procedure and clinical results in infants with microtropic highlight the potential of the system as a screening apparatus and for the exact measurement of small and large squint angles. Usually even 1-year-old children can cooperate well enough to get good-quality pictures in binocular fixation. The new

  12. Non-mydriatic video ophthalmoscope to measure fast temporal changes of the human retina

    Science.gov (United States)

    Tornow, Ralf P.; Kolář, Radim; Odstrčilík, Jan

    2015-07-01

    The analysis of fast temporal changes of the human retina can be used to get insight to normal physiological behavior and to detect pathological deviations. This can be important for the early detection of glaucoma and other eye diseases. We developed a small, lightweight, USB powered video ophthalmoscope that allows taking video sequences of the human retina with at least 25 frames per second without dilating the pupil. Short sequences (about 10 s) of the optic nerve head (20° x 15°) are recorded from subjects and registered offline using two-stage process (phase correlation and Lucas-Kanade approach) to compensate for eye movements. From registered video sequences, different parameters can be calculated. Two applications are described here: measurement of (i) cardiac cycle induced pulsatile reflection changes and (ii) eye movements and fixation pattern. Cardiac cycle induced pulsatile reflection changes are caused by changing blood volume in the retina. Waveform and pulse parameters like amplitude and rise time can be measured in any selected areas within the retinal image. Fixation pattern ΔY(ΔX) can be assessed from eye movements during video acquisition. The eye movements ΔX[t], ΔY[t] are derived from image registration results with high temporal (40 ms) and spatial (1,86 arcmin) resolution. Parameters of pulsatile reflection changes and fixation pattern can be affected in beginning glaucoma and the method described here may support early detection of glaucoma and other eye disease.

  13. New pediatric vision screener employing polarization-modulated, retinal-birefringence-scanning-based strabismus detection and bull's eye focus detection with an improved target system: opto-mechanical design and operation

    Science.gov (United States)

    Irsch, Kristina; Gramatikov, Boris I.; Wu, Yi-Kai; Guyton, David L.

    2014-06-01

    Amblyopia ("lazy eye") is a major public health problem, caused by misalignment of the eyes (strabismus) or defocus. If detected early in childhood, there is an excellent response to therapy, yet most children are detected too late to be treated effectively. Commercially available vision screening devices that test for amblyopia's primary causes can detect strabismus only indirectly and inaccurately via assessment of the positions of external light reflections from the cornea, but they cannot detect the anatomical feature of the eyes where fixation actually occurs (the fovea). Our laboratory has been developing technology to detect true foveal fixation, by exploiting the birefringence of the uniquely arranged Henle fibers delineating the fovea using retinal birefringence scanning (RBS), and we recently described a polarization-modulated approach to RBS that enables entirely direct and reliable detection of true foveal fixation, with greatly enhanced signal-to-noise ratio and essentially independent of corneal birefringence (a confounding variable with all polarization-sensitive ophthalmic technology). Here, we describe the design and operation of a new pediatric vision screener that employs polarization-modulated, RBS-based strabismus detection and bull's eye focus detection with an improved target system, and demonstrate the feasibility of this new approach.

  14. New pediatric vision screener employing polarization-modulated, retinal-birefringence-scanning-based strabismus detection and bull's eye focus detection with an improved target system: opto-mechanical design and operation.

    Science.gov (United States)

    Irsch, Kristina; Gramatikov, Boris I; Wu, Yi-Kai; Guyton, David L

    2014-06-01

    Amblyopia ("lazy eye") is a major public health problem, caused by misalignment of the eyes (strabismus) or defocus. If detected early in childhood, there is an excellent response to therapy, yet most children are detected too late to be treated effectively. Commercially available vision screening devices that test for amblyopia's primary causes can detect strabismus only indirectly and inaccurately via assessment of the positions of external light reflections from the cornea, but they cannot detect the anatomical feature of the eyes where fixation actually occurs (the fovea). Our laboratory has been developing technology to detect true foveal fixation, by exploiting the birefringence of the uniquely arranged Henle fibers delineating the fovea using retinal birefringence scanning (RBS), and we recently described a polarization-modulated approach to RBS that enables entirely direct and reliable detection of true foveal fixation, with greatly enhanced signal-to-noise ratio and essentially independent of corneal birefringence (a confounding variable with all polarization-sensitive ophthalmic technology). Here, we describe the design and operation of a new pediatric vision screener that employs polarization-modulated, RBS-based strabismus detection and bull's eye focus detection with an improved target system, and demonstrate the feasibility of this new approach.

  15. Scanning mid-IR laser apparatus with eye tracking for refractive surgery

    Science.gov (United States)

    Telfair, William B.; Yoder, Paul R., Jr.; Bekker, Carsten; Hoffman, Hanna J.; Jensen, Eric F.

    1999-06-01

    A robust, real-time, dynamic eye tracker has been integrated with the short pulse mid-infrared laser scanning delivery system previously described. This system employs a Q- switched Nd:YAG laser pumped optical parametric oscillator operating at 2.94 micrometers. Previous ablation studies on human cadaver eyes and in-vivo cat eyes demonstrated very smooth ablations with extremely low damage levels similar to results with an excimer. A 4-month healing study with cats indicated no adverse healing effects. In order to treat human eyes, the tracker is required because the eyes move during the procedure due to both voluntary and involuntary motions such as breathing, heartbeat, drift, loss of fixation, saccades and microsaccades. Eye tracking techniques from the literature were compared. A limbus tracking system was best for this application. Temporal and spectral filtering techniques were implemented to reduce tracking errors, reject stray light, and increase signal to noise ratio. The expanded-capability system (IRVision AccuScan 2000 Laser System) has been tested in the lab on simulated eye targets, glass eyes, cadaver eyes, and live human subjects. Circular targets ranging from 10-mm to 14-mm diameter were successfully tracked. The tracker performed beyond expectations while the system performed myopic photorefractive keratectomy procedures on several legally blind human subjects.

  16. Gender Classification Based on Eye Movements: A Processing Effect During Passive Face Viewing.

    Science.gov (United States)

    Sammaknejad, Negar; Pouretemad, Hamidreza; Eslahchi, Changiz; Salahirad, Alireza; Alinejad, Ashkan

    2017-01-01

    Studies have revealed superior face recognition skills in females, partially due to their different eye movement strategies when encoding faces. In the current study, we utilized these slight but important differences and proposed a model that estimates the gender of the viewers and classifies them into two subgroups, males and females. An eye tracker recorded participant's eye movements while they viewed images of faces. Regions of interest (ROIs) were defined for each face. Results showed that the gender dissimilarity in eye movements was not due to differences in frequency of fixations in the ROI s per se. Instead, it was caused by dissimilarity in saccade paths between the ROIs. The difference enhanced when saccades were towards the eyes. Females showed significant increase in transitions from other ROI s to the eyes. Consequently, the extraction of temporal transient information of saccade paths through a transition probability matrix, similar to a first order Markov chain model, significantly improved the accuracy of the gender classification results.

  17. Signalling properties of identified deep cerebellar nuclear neurons related to eye and head movements in the alert cat.

    Science.gov (United States)

    Gruart, A; Delgado-García, J M

    1994-07-01

    1. The spike activity of deep cerebellar nuclear neurons was recorded in the alert cat during spontaneous and during vestibularly and visually induced eye movements. 2. Neurons were classified according to their location in the nuclei, their antidromic activation from projection sites, their sensitivity to eye position and velocity during spontaneous eye movements, and their responses to vestibular and optokinetic stimuli. 3. Type I EPV (eye position and velocity) neurons were located mainly in the posterior part of the fastigial nucleus and activated antidromically almost exclusively from the medial longitudinal fasciculus close to the oculomotor complex. These neurons, reported here for the first time, increased their firing rate during saccades and eye fixations towards the contralateral hemifield. Their position sensitivity to eye fixations in the horizontal plane was 5.3 +/- 2.6 spikes s-1 deg-1 (mean +/- S.D.). Eye velocity sensitivity during horizontal saccades was 0.71 +/- 0.52 spikes s-1 deg-1 s-1. Variability of their firing rate during a given eye fixation was higher than that shown by abducens motoneurons. 4. Type I EPV neurons increased their firing rate during ipsilateral head rotations at 0.5 Hz with a mean phase lead over eye position of 95.3 +/- 9.5 deg. They were also activated by contralateral optokinetic stimulation at 30 deg s-1. Their sensitivity to eye position and velocity in the horizontal plane during vestibular and optokinetic stimuli yielded values similar to those obtained for spontaneous eye movements. 5. Type II neurons were located in both fastigial and dentate nuclei and were activated antidromically from the restiform body, the medial longitudinal fasciculus close to the oculomotor complex, the red nucleus and the pontine nuclei. Type II neurons were not related to spontaneous eye movements. These neurons increased their firing rate in response to contralateral head rotation and during ipsilateral optokinetic stimulation, and

  18. Comparison of Outcomes of Operatively Treated Bicondylar Tibial Plateau Fractures by External Fixation and Internal Fixation

    Directory of Open Access Journals (Sweden)

    CC Chan

    2012-03-01

    Full Text Available The outcome of bicondylar tibial plateau fractures treated with either external fixation (35 patients or internal fixation (24 patients was reviewed. Outcome measures included the Rasmussen score, clinical complications, development of osteoarthritis and the requirement for total knee replacement (TKR. Twenty-two (92% anatomical reductions were achieved in the internal fixation group compared to 27 (77% in the external fixation group. Infective complications were more common in the external fixation group (9 patients, 26% due to pin tract infection. There were no deep infections in the internal fixation group. The mean Rasmussen score was not significantly different (mean score 32 in external fixation and 29 in internal fixation between the two groups and the incidence of osteoarthritis was the same in both groups. Four patients in the external fixation group underwent a TKR compared to 5 patients in the internal fixation group. Bicondylar tibial plateau fractures have similar outcomes following external or internal fixation.

  19. Validation of mobile eye tracking as novel and efficient means for differentiating progressive supranuclear palsy from Parkinson’s disease

    Directory of Open Access Journals (Sweden)

    Svenja eMarx

    2012-12-01

    Full Text Available Background: The decreased ability to carry out vertical saccades is a key symptom of Progressive Supranuclear Palsy (PSP. Objective measurement devices can help to reliably detect subtle eye-movement disturbances to improve sensitivity and specificity of the clinical diagnosis. The present study aims at transferring findings from restricted stationary video-oculography to a wearable head-mounted device, which can be readily applied in clinical practice.Methods: We investigated the eye movements in 10 possible or probable PSP patients, 11 Parkinson’s disease (PD patients and 10 age-matched healthy controls (HC using a mobile, gaze-driven video camera setup (EyeSeeCam. Ocular movements were analyzed during a standardized fixation protocol and in an unrestricted real-life scenario while walking along a corridor.Results: The EyeSeeCam detected prominent impairment of both saccade velocity and amplitude in PSP patients, differentiating them from PD and HCs. Differences were particularly evident for saccades in the vertical plane, and stronger for saccades than for other eye movements. Differences were more pronounced during the standardized protocol than in the real-life scenario. Conclusions: Combined analysis of saccade velocity and saccade amplitude during the fixation protocol with the EyeSeeCam provides a simple, rapid (< 20s and reliable tool to differentiate clinically established PSP patients from PD and HCs. As such, our findings prepare the ground for using wearable eye-tracking in patients with uncertain diagnoses.

  20. Eye-movements and ongoing task processing.

    Science.gov (United States)

    Burke, David T; Meleger, Alec; Schneider, Jeffrey C; Snyder, Jim; Dorvlo, Atsu S S; Al-Adawi, Samir

    2003-06-01

    This study tests the relation between eye-movements and thought processing. Subjects were given specific modality tasks (visual, gustatory, kinesthetic) and assessed on whether they responded with distinct eye-movements. Some subjects' eye-movements reflected ongoing thought processing. Instead of a universal pattern, as suggested by the neurolinguistic programming hypothesis, this study yielded subject-specific idiosyncratic eye-movements across all modalities. Included is a discussion of the neurolinguistic programming hypothesis regarding eye-movements and its implications for the eye-movement desensitization and reprocessing theory.

  1. Computerized evaluation of deambulatory pattern before and after visual rehabilitation treatment performed with biofeedback in visually impaired patients suffering from macular degeneration

    Directory of Open Access Journals (Sweden)

    Fernanda Pacella

    2016-09-01

    Full Text Available Aims: The aim of this study was double: the primary endpoint was to evaluate the efficacy of visual rehabilitation of visually impaired patients with macular degeneration (AMD. The secondary endpoint was to assess the effect of rehabilitation treatment on the ambulatory pattern using a computerized evaluation of walking, focusing the attention on space-time parameters that are influenced in patients with visual impairment. Methods: 10 patients with AMD were enrolled, 6 males and 4 females, and examined 15 eyes, at Department of Sense Organs, Faculty of Medicine and Dentistry Sapienza University of Rome, Italy. Visual rehabilitation was carried out with the use of a microperimeter MP1 using the examination of biofeedback. Patients are asked to move their eyes in coordination with an audible feedback that alerts the patient when he is setting properly the fixation target previously selected. All patients were subjected to 10 sessions lasting 15 minutes each for each eye, 1 time per week. The best corrected visual acuity (BCVA was assessed by far with the ETDRS optotype IN LOG MAR, and by close to 25 cm by adding + 4 ball (addition to near to the BCVA. For each eye the PB ( print body on the distance of 25 cm was measured; It fixation stability for 30 seconds was examined by microperimeter. Gait Analysis was performed with system ELITE BTS SpA (Milan, Italy. Results: At the end of the rehabilitation treatment with biofeedback it was found a marked improvement in BCVA. The BCVA before the rehabilitation treatment was ETDRS 12 LETTERS = 0.86 logMAR. At the end of the visual rehabilitation 16 LETTERS = 0.78 logMAR. The near visual acuity presented a decrease of the printer body measurement (PB and a statistically significant improvement in the fixation stability. Analysis of the spatial and temporal parameters of gait cycle, aimed at assessing the global aspects of gait (speed, rhythm, symmetry, fluidity, dynamic balance showed no significant changes

  2. Loneliness and hypervigilance to social cues in females: an eye-tracking study.

    Directory of Open Access Journals (Sweden)

    Gerine M A Lodder

    Full Text Available The goal of the present study was to examine whether lonely individuals differ from nonlonely individuals in their overt visual attention to social cues. Previous studies showed that loneliness was related to biased post-attentive processing of social cues (e.g., negative interpretation bias, but research on whether lonely and nonlonely individuals also show differences in an earlier information processing stage (gazing behavior is very limited. A sample of 25 lonely and 25 nonlonely students took part in an eye-tracking study consisting of four tasks. We measured gazing (duration, number of fixations and first fixation at the eyes, nose and mouth region of faces expressing emotions (Task 1, at emotion quadrants (anger, fear, happiness and neutral expression (Task 2, at quadrants with positive and negative social and nonsocial images (Task 3, and at the facial area of actors in video clips with positive and negative content (Task 4. In general, participants tended to gaze most often and longest at areas that conveyed most social information, such as the eye region of the face (T1, and social images (T3. Participants gazed most often and longest at happy faces (T2 in still images, and more often and longer at the facial area in negative than in positive video clips (T4. No differences occurred between lonely and nonlonely participants in their gazing times and frequencies, nor at first fixations at social cues in the four different tasks. Based on this study, we found no evidence that overt visual attention to social cues differs between lonely and nonlonely individuals. This implies that biases in social information processing of lonely individuals may be limited to other phases of social information processing. Alternatively, biased overt attention to social cues may only occur under specific conditions, for specific stimuli or for specific lonely individuals.

  3. Using the eye fixation speculum as an adjunct to pterygium surgery.

    LENUS (Irish Health Repository)

    Mulhern, M G

    2012-02-03

    A technique is described that overcomes the two biggest problems facing the surgeon when dissecting a pterygium from the cornea-bleeding and eye movement. Our technique however, requires only minimal anesthesia (topical and subconjunctival) and the use of a disposable speculum and suction ring. An added advantage is this particular speculum gives good exposure of the superior bulbar conjunctiva; this facilitates harvesting a conjunctival autograft.

  4. Cephalomedullary fixation for femoral neck/intertrochanteric and ipsilateral shaft fractures: surgical tips and pitfalls

    Directory of Open Access Journals (Sweden)

    Bali Kamal

    2013-02-01

    Full Text Available 【Abstract】Objective: Surgical management op-tions for femoral shaft fracture and ipsilateral proximal fe-mur fracture vary from single-implant to double-implant fixation. Cephalomedullary fixation in such fractures has rela-tive advantages over other techniques especially because of less soft tissue dissection and immediate postoperative weight bearing with accelerated rehabilitation. However, the surgery is technically demanding and there is a paucity of literature describing the surgical techniques for this fixation. The aim of the study was to describe the surgical technique of cephalomedullary fixation for femoral shaft fracture and ipsilateral proximal femur fracture. Methods: Sixteen cases (10 males and 6 females with a mean age of 41.8 years of ipsilateral proximal femur and shaft fractures were treated by single-stage cephalomedullary fixa-tion at tertiary level trauma center in northern India. The fractures were classified according to AO classification. An intraoperative record of duration of surgery as well as tech-nical challenges unique to each fracture pattern was kept for all the patients. Results: The most common proximal femoral pattern was AO B2.1 observed in 9 of our patients. The AO B2.3 fractures were seen in 4 patients while the AO A1.2 fractures in 3 patients. Four of the AO B2.1 and 2 of the AO B2.3 frac-tures required open reduction with Watson-Jones approach. The mean operative time was around 78 minutes, which tended to decrease as the surgical experience increased. There was only one case of malreduction, which required revision surgery. Conclusion: Combination of ipsilateral femoral shaft fracture and neck/intertrochanteric fracture is a difficult frac-ture pattern for trauma surgeons. Cephalomedullary nail is an excellent implant for such fractures but it requires careful insertion to avoid complications. Surgery is technically de-manding with a definite learning curve. Nevertheless, a ma-jority of these

  5. Usability Analysis of Online Bank Login Interface Based on Eye Tracking Experiment

    Directory of Open Access Journals (Sweden)

    Xiaofang YUAN

    2014-02-01

    Full Text Available With the rapid development of information technology and rapid popularization of online banking, it is used by the more and more consumers. Studying on the usability of online banking interface, improving the user-friendliness of web interface, and enhancing attraction of bank website, which have gradually become the basic network marketing strategy of the banks. Therefore, this study took three banks as an example to record subjects’’ eye tracking data of time to first fixation, fixation duration and blink count and so on by using Tobii T60XL Eye Tracking equipment, while they login online banking web interface, and analyzed that the factors of webpage layout, colors, the amount of information presentation which impacts on the usability of online banking login interface. The results shows that the login entry, account login information and other key control buttons should be placed in the upper left corner to quickly lock the target, and the interface should have a moderate amount of information presentation, the appropriate proportion, reasonable font size settings, harmonious, simple, and warmth design style.

  6. Word segmentation by alternating colors facilitates eye guidance in Chinese reading.

    Science.gov (United States)

    Zhou, Wei; Wang, Aiping; Shu, Hua; Kliegl, Reinhold; Yan, Ming

    2018-02-12

    During sentence reading, low spatial frequency information afforded by spaces between words is the primary factor for eye guidance in spaced writing systems, whereas saccade generation for unspaced writing systems is less clear and under debate. In the present study, we investigated whether word-boundary information, provided by alternating colors (consistent or inconsistent with word-boundary information) influences saccade-target selection in Chinese. In Experiment 1, as compared to a baseline (i.e., uniform color) condition, word segmentation with alternating color shifted fixation location towards the center of words. In contrast, incorrect word segmentation shifted fixation location towards the beginning of words. In Experiment 2, we used a gaze-contingent paradigm to restrict the color manipulation only to the upcoming parafoveal words and replicated the results, including fixation location effects, as observed in Experiment 1. These results indicate that Chinese readers are capable of making use of parafoveal word-boundary knowledge for saccade generation, even if such information is unfamiliar to them. The present study provides novel support for the hypothesis that word segmentation is involved in the decision about where to fixate next during Chinese reading.

  7. "Gaze Leading": Initiating Simulated Joint Attention Influences Eye Movements and Choice Behavior

    Science.gov (United States)

    Bayliss, Andrew P.; Murphy, Emily; Naughtin, Claire K.; Kritikos, Ada; Schilbach, Leonhard; Becker, Stefanie I.

    2013-01-01

    Recent research in adults has made great use of the gaze cuing paradigm to understand the behavior of the follower in joint attention episodes. We implemented a gaze leading task to investigate the initiator--the other person in these triadic interactions. In a series of gaze-contingent eye-tracking studies, we show that fixation dwell time upon…

  8. The effect of human engagement depicted in contextual photographs on the visual attention patterns of adults with traumatic brain injury.

    Science.gov (United States)

    Thiessen, Amber; Brown, Jessica; Beukelman, David; Hux, Karen

    2017-09-01

    Photographs are a frequently employed tool for the rehabilitation of adults with traumatic brain injury (TBI). Speech-language pathologists (SLPs) working with these individuals must select photos that are easily identifiable and meaningful to their clients. In this investigation, we examined the visual attention response to camera- (i.e., depicted human figure looking toward camera) and task-engaged (i.e., depicted human figure looking at and touching an object) contextual photographs for a group of adults with TBI and a group of adults without neurological conditions. Eye-tracking technology served to accurately and objectively measure visual fixations. Although differences were hypothesized given the cognitive deficits associated with TBI, study results revealed little difference in the visual fixation patterns of adults with and without TBI. Specifically, both groups of participants tended to fixate rapidly on the depicted human figure and fixate more on objects in which a human figure was task-engaged than when a human figure was camera-engaged. These results indicate that strategic placement of human figures in a contextual photograph may modify the way in which individuals with TBI visually attend to and interpret photographs. In addition, task-engagement appears to have a guiding effect on visual attention that may be of benefit to SLPs hoping to select more effective contextual photographs for their clients with TBI. Finally, the limited differences in visual attention patterns between individuals with TBI and their age and gender matched peers without neurological impairments indicates that these two groups find similar photograph regions to be worthy of visual fixation. Readers will gain knowledge regarding the photograph selection process for individuals with TBI. In addition, readers will be able to identify camera- and task-engaged photographs and to explain why task-engagement may be a beneficial component of contextual photographs. Copyright © 2017

  9. The eye-tracking of social stimuli in patients with Rett syndrome and autism spectrum disorders: a pilot study

    Directory of Open Access Journals (Sweden)

    José Salomão Schwartzman

    2015-05-01

    Full Text Available Objective To compare visual fixation at social stimuli in Rett syndrome (RT and autism spectrum disorders (ASD patients. Method Visual fixation at social stimuli was analyzed in 14 RS female patients (age range 4-30 years, 11 ASD male patients (age range 4-20 years, and 17 children with typical development (TD. Patients were exposed to three different pictures (two of human faces and one with social and non-social stimuli presented for 8 seconds each on the screen of a computer attached to an eye-tracker equipment. Results Percentage of visual fixation at social stimuli was significantly higher in the RS group compared to ASD and even to TD groups. Conclusion Visual fixation at social stimuli seems to be one more endophenotype making RS to be very different from ASD.

  10. Environmental and biogeochemical controls on N2 fixation in ombrotrophic peatlands

    Science.gov (United States)

    Zivkovic, T.; Moore, T. R.

    2017-12-01

    Northern peatlands have low atmospheric nitrogen (N) inputs and acquire N mostly via biological, microbially-driven N2-fixation. Little is known about rates and controls on N2-fixation in ombrotrophic bogs. We conducted two studies to test environmental and biogeochemical controls on N2-fixation. First, we used acetylene reduction assay (ARA) calibrated with 15N2 tracer to measure N2-fixation rates in three species of Sphagnum mosses along a hydrological gradient (beaver pond, hollow and hummock in bog margin and in bog) at Mer Bleue bog from June-October 2013 and May - November 2014. We tested the following controls: moisture availability, temperature, and PAR. The largest ARA rates throughout both seasons occurred in the pond in floating Sphagnum cuspidatum mats (50.3 ± 12.9 μmol m-2 d-1 Mean ± SE), which were up to 2.5 times larger than the rates found in the driest hummock site. There was a significant seasonal peak in both years in July and early August that coincided with the peak of the air temperature. In fact, 45% of the variance of N2 fixation rates over the two field seasons was explained by rain events, water table fluctuations and the surface peat temperature (multiple regression analysis, n = 539). Our results highlight the potential impact of climate change, namely negative effects due to potential droughts and positive effect of warming, on N2 fixation patterns in ombrotrophic peatlands. Secondly, we tested stoichiometric controls (Sphagnum tissue N and phosphorous (P) ratio) of N2-fixation. In a controlled environment, we selected eight study sites along a latitudinal gradient from temperate, boreal to subarctic zone in eastern Canada. We found that decreasing N:P ratio corresponded to increasing N2-fixation. N:P explained 65% of the variance in N2-fixation in hollows but only 20% in hummocks. Changes in neither N or P concentration alone explained the increase in N2-fixation better than N:P ratio. We interpret that the difference between

  11. How Life History Can Sway the Fixation Probability of Mutants

    Science.gov (United States)

    Li, Xiang-Yi; Kurokawa, Shun; Giaimo, Stefano; Traulsen, Arne

    2016-01-01

    In this work, we study the effects of demographic structure on evolutionary dynamics when selection acts on reproduction, survival, or both. In contrast to the previously discovered pattern that the fixation probability of a neutral mutant decreases while the population becomes younger, we show that a mutant with a constant selective advantage may have a maximum or a minimum of the fixation probability in populations with an intermediate fraction of young individuals. This highlights the importance of life history and demographic structure in studying evolutionary dynamics. We also illustrate the fundamental differences between selection on reproduction and selection on survival when age structure is present. In addition, we evaluate the relative importance of size and structure of the population in determining the fixation probability of the mutant. Our work lays the foundation for also studying density- and frequency-dependent effects in populations when demographic structures cannot be neglected. PMID:27129737

  12. An eye movement based reading intervention in lexical and segmental readers with acquired dyslexia.

    Science.gov (United States)

    Ablinger, Irene; von Heyden, Kerstin; Vorstius, Christian; Halm, Katja; Huber, Walter; Radach, Ralph

    2014-01-01

    Due to their brain damage, aphasic patients with acquired dyslexia often rely to a greater extent on lexical or segmental reading procedures. Thus, therapy intervention is mostly targeted on the more impaired reading strategy. In the present work we introduce a novel therapy approach based on real-time measurement of patients' eye movements as they attempt to read words. More specifically, an eye movement contingent technique of stepwise letter de-masking was used to support sequential reading, whereas fixation-dependent initial masking of non-central letters stimulated a lexical (parallel) reading strategy. Four lexical and four segmental readers with acquired central dyslexia received our intensive reading intervention. All participants showed remarkable improvements as evident in reduced total reading time, a reduced number of fixations per word and improved reading accuracy. Both types of intervention led to item-specific training effects in all subjects. A generalisation to untrained items was only found in segmental readers after the lexical training. Eye movement analyses were also used to compare word processing before and after therapy, indicating that all patients, with one exclusion, maintained their preferred reading strategy. However, in several cases the balance between sequential and lexical processing became less extreme, indicating a more effective individual interplay of both word processing routes.

  13. Fetal Eye Movements on Magnetic Resonance Imaging

    Science.gov (United States)

    Woitek, Ramona; Kasprian, Gregor; Lindner, Christian; Stuhr, Fritz; Weber, Michael; Schöpf, Veronika; Brugger, Peter C.; Asenbaum, Ulrika; Furtner, Julia; Bettelheim, Dieter; Seidl, Rainer; Prayer, Daniela

    2013-01-01

    Objectives Eye movements are the physical expression of upper fetal brainstem function. Our aim was to identify and differentiate specific types of fetal eye movement patterns using dynamic MRI sequences. Their occurrence as well as the presence of conjugated eyeball motion and consistently parallel eyeball position was systematically analyzed. Methods Dynamic SSFP sequences were acquired in 72 singleton fetuses (17–40 GW, three age groups [17–23 GW, 24–32 GW, 33–40 GW]). Fetal eye movements were evaluated according to a modified classification originally published by Birnholz (1981): Type 0: no eye movements; Type I: single transient deviations; Type Ia: fast deviation, slower reposition; Type Ib: fast deviation, fast reposition; Type II: single prolonged eye movements; Type III: complex sequences; and Type IV: nystagmoid. Results In 95.8% of fetuses, the evaluation of eye movements was possible using MRI, with a mean acquisition time of 70 seconds. Due to head motion, 4.2% of the fetuses and 20.1% of all dynamic SSFP sequences were excluded. Eye movements were observed in 45 fetuses (65.2%). Significant differences between the age groups were found for Type I (p = 0.03), Type Ia (p = 0.031), and Type IV eye movements (p = 0.033). Consistently parallel bulbs were found in 27.3–45%. Conclusions In human fetuses, different eye movement patterns can be identified and described by MRI in utero. In addition to the originally classified eye movement patterns, a novel subtype has been observed, which apparently characterizes an important step in fetal brainstem development. We evaluated, for the first time, eyeball position in fetuses. Ultimately, the assessment of fetal eye movements by MRI yields the potential to identify early signs of brainstem dysfunction, as encountered in brain malformations such as Chiari II or molar tooth malformations. PMID:24194885

  14. Fetal eye movements on magnetic resonance imaging.

    Science.gov (United States)

    Woitek, Ramona; Kasprian, Gregor; Lindner, Christian; Stuhr, Fritz; Weber, Michael; Schöpf, Veronika; Brugger, Peter C; Asenbaum, Ulrika; Furtner, Julia; Bettelheim, Dieter; Seidl, Rainer; Prayer, Daniela

    2013-01-01

    Eye movements are the physical expression of upper fetal brainstem function. Our aim was to identify and differentiate specific types of fetal eye movement patterns using dynamic MRI sequences. Their occurrence as well as the presence of conjugated eyeball motion and consistently parallel eyeball position was systematically analyzed. Dynamic SSFP sequences were acquired in 72 singleton fetuses (17-40 GW, three age groups [17-23 GW, 24-32 GW, 33-40 GW]). Fetal eye movements were evaluated according to a modified classification originally published by Birnholz (1981): Type 0: no eye movements; Type I: single transient deviations; Type Ia: fast deviation, slower reposition; Type Ib: fast deviation, fast reposition; Type II: single prolonged eye movements; Type III: complex sequences; and Type IV: nystagmoid. In 95.8% of fetuses, the evaluation of eye movements was possible using MRI, with a mean acquisition time of 70 seconds. Due to head motion, 4.2% of the fetuses and 20.1% of all dynamic SSFP sequences were excluded. Eye movements were observed in 45 fetuses (65.2%). Significant differences between the age groups were found for Type I (p = 0.03), Type Ia (p = 0.031), and Type IV eye movements (p = 0.033). Consistently parallel bulbs were found in 27.3-45%. In human fetuses, different eye movement patterns can be identified and described by MRI in utero. In addition to the originally classified eye movement patterns, a novel subtype has been observed, which apparently characterizes an important step in fetal brainstem development. We evaluated, for the first time, eyeball position in fetuses. Ultimately, the assessment of fetal eye movements by MRI yields the potential to identify early signs of brainstem dysfunction, as encountered in brain malformations such as Chiari II or molar tooth malformations.

  15. Eighth international congress on nitrogen fixation

    Energy Technology Data Exchange (ETDEWEB)

    1990-01-01

    This volume contains the proceedings of the Eighth International Congress on Nitrogen Fixation held May 20--26, 1990 in Knoxville, Tennessee. The volume contains abstracts of individual presentations. Sessions were entitled Recent Advances in the Chemistry of Nitrogen Fixation, Plant-microbe Interactions, Limiting Factors of Nitrogen Fixation, Nitrogen Fixation and the Environment, Bacterial Systems, Nitrogen Fixation in Agriculture and Industry, Plant Function, and Nitrogen Fixation and Evolution.

  16. Outcomes of iris-claw anterior chamber versus iris-fixated foldable intraocular lens in subluxated lens secondary to Marfan syndrome.

    Science.gov (United States)

    Hirashima, Denise E; Soriano, Eduardo S; Meirelles, Rodrigo L; Alberti, Gustave N; Nosé, Walton

    2010-08-01

    To compare the outcome of phacoemulsification using 2 different iris-fixation techniques for intraocular lens (IOL) replacement, a foldable posterior chamber IOL (PCIOL; AcrySof MA60AC, Alcon Laboratories Inc, Fort Worth, TX) and an iris-claw anterior chamber IOL (ACIOL; Artisan, Ophtec BV), for treatment of subluxated lenses in patients with Marfan syndrome (MFS). Randomized, controlled trial. A total of 31 eyes of 16 patients with subluxated lenses associated with MFS and a preoperative corrected visual acuity (CVA) IOL type. Preoperative and postoperative ophthalmologic examination, optical coherence tomography, and endothelial cell counts were performed. We recorded CVA results at 3, 6, and 12 months, complications, endothelial cell loss, and central retinal thickness. In the iris-fixated PCIOL group, CVA was significantly improved at 3 (P = 0.011; n = 16), 6 (P = 0.006; n = 16), and 12 months (P = 0.002; n = 16). In the iris-claw ACIOL group, CVA was significantly improved at 3 (P = 0.001; n=15), 6 (P = 0.001; n = 15), and 12 months (P = 0.009; n = 12). The CVA results did not differ significantly between groups. Dislocation of the IOL occurred in 3 of 16 (18.75%) eyes in the PCIOL group. Retinal detachment occurred in 3 eyes (2 in the PCIOL group and 1 in the ACIOL group) and was successfully repaired. Postoperative foveal tomograms in both groups revealed a decrease in the mean foveal thickness (MFT; IOL dislocation tended to occur more frequently in the iris-fixated PCIOL group, the difference was not significant. At 6 months postoperatively, all study patients tended to have a thinner MFT. None of the patients in either group developed cystoid macular edema. Copyright 2010 American Academy of Ophthalmology. Published by Elsevier Inc. All rights reserved.

  17. Attention and Recall of Point-of-sale Tobacco Marketing: A Mobile Eye-Tracking Pilot Study

    Directory of Open Access Journals (Sweden)

    Maansi Bansal-Travers

    2016-01-01

    Full Text Available  Introduction: As tobacco advertising restrictions have increased, the retail ‘power wall’ behind the counter is increasingly invaluable for marketing tobacco products. Objective: The primary objectives of this pilot study were 3-fold: (1 evaluate the attention paid/fixations on the area behind the cash register where tobacco advertising is concentrated and tobacco products are displayed in a real-world setting, (2 evaluate the duration (dwell-time of these fixations, and (3 evaluate the recall of advertising displayed on the tobacco power wall. Methods: Data from 13 Smokers (S and 12 Susceptible or non-daily Smokers (SS aged 180–30 from a mobile eye-tracking study. Mobile-eye tracking technology records the orientation (fixation and duration (dwell-time of visual attention. Participants were randomized to one of three purchase tasks at a convenience store: Candy bar Only (CO; N = 10, Candy bar + Specified cigarette Brand (CSB; N = 6, and Candy bar + cigarette Brand of their Choice (CBC; N = 9. A post-session survey evaluated recall of tobacco marketing. Key outcomes were fixations and dwell-time on the cigarette displays at the point-of-sale. Results: Participants spent a median time of 44 seconds during the standardized time evaluated and nearly three-quarters (72% fixated on the power wall during their purchase, regardless of smoking status (S: 77%, SS: 67% or purchase task (CO: 44%, CSB: 71%, CBC: 100%. In the post session survey, nearly all participants (96% indicated they noticed a cigarette brand and 64% were able to describe a specific part of the tobacco wall or recall a promotional offer. Conclusions: Consumers are exposed to point-of-sale tobacco marketing, regardless of smoking status. FDA should consider regulations that limit exposure to point-of-sale tobacco marketing among consumers.

  18. Attention and Recall of Point-of-sale Tobacco Marketing: A Mobile Eye-Tracking Pilot Study.

    Science.gov (United States)

    Bansal-Travers, Maansi; Adkison, Sarah E; O'Connor, Richard J; Thrasher, James F

    2016-01-01

    As tobacco advertising restrictions have increased, the retail 'power wall' behind the counter is increasingly invaluable for marketing tobacco products. The primary objectives of this pilot study were 3-fold: (1) evaluate the attention paid/fixations on the area behind the cash register where tobacco advertising is concentrated and tobacco products are displayed in a real-world setting, (2) evaluate the duration (dwell-time) of these fixations, and (3) evaluate the recall of advertising displayed on the tobacco power wall. Data from 13 Smokers (S) and 12 Susceptible or non-daily Smokers (SS) aged 180-30 from a mobile eye-tracking study. Mobile-eye tracking technology records the orientation (fixation) and duration (dwell-time) of visual attention. Participants were randomized to one of three purchase tasks at a convenience store: Candy bar Only (CO; N = 10), Candy bar + Specified cigarette Brand (CSB; N = 6), and Candy bar + cigarette Brand of their Choice (CBC; N = 9). A post-session survey evaluated recall of tobacco marketing. Key outcomes were fixations and dwell-time on the cigarette displays at the point-of-sale. Participants spent a median time of 44 seconds during the standardized time evaluated and nearly three-quarters (72%) fixated on the power wall during their purchase, regardless of smoking status (S: 77%, SS: 67%) or purchase task (CO: 44%, CSB: 71%, CBC: 100%). In the post session survey, nearly all participants (96%) indicated they noticed a cigarette brand and 64% were able to describe a specific part of the tobacco wall or recall a promotional offer. Consumers are exposed to point-of-sale tobacco marketing, regardless of smoking status. FDA should consider regulations that limit exposure to point-of-sale tobacco marketing among consumers.

  19. Isotopes in biological dinitrogen fixation

    Energy Technology Data Exchange (ETDEWEB)

    1978-10-01

    Nineteen papers were presented at the conference. Some topics discussed are as follows: biochemistry and genetics of dinitrogen fixation; genetics of the Rhizobium-legume symbiosis and of the nitrogen-fixing bacteria; studies on nonsymbiotic dinitrogen fixation in grass-bacteria associations and blue--green algae; use of /sup 15/N and /sup 13/N for the assay of dinitrogen fixation; effects of management practices on dinitrogen fixation; economy of C and N in nitrogen-fixing legumes; and survey of international and national programs on dinitrogen fixation. (HLW)

  20. Modeling eye movements in visual agnosia with a saliency map approach: bottom-up guidance or top-down strategy?

    Science.gov (United States)

    Foulsham, Tom; Barton, Jason J S; Kingstone, Alan; Dewhurst, Richard; Underwood, Geoffrey

    2011-08-01

    Two recent papers (Foulsham, Barton, Kingstone, Dewhurst, & Underwood, 2009; Mannan, Kennard, & Husain, 2009) report that neuropsychological patients with a profound object recognition problem (visual agnosic subjects) show differences from healthy observers in the way their eye movements are controlled when looking at images. The interpretation of these papers is that eye movements can be modeled as the selection of points on a saliency map, and that agnosic subjects show an increased reliance on visual saliency, i.e., brightness and contrast in low-level stimulus features. Here we review this approach and present new data from our own experiments with an agnosic patient that quantifies the relationship between saliency and fixation location. In addition, we consider whether the perceptual difficulties of individual patients might be modeled by selectively weighting the different features involved in a saliency map. Our data indicate that saliency is not always a good predictor of fixation in agnosia: even for our agnosic subject, as for normal observers, the saliency-fixation relationship varied as a function of the task. This means that top-down processes still have a significant effect on the earliest stages of scanning in the setting of visual agnosia, indicating severe limitations for the saliency map model. Top-down, active strategies-which are the hallmark of our human visual system-play a vital role in eye movement control, whether we know what we are looking at or not. Copyright © 2011 Elsevier Ltd. All rights reserved.

  1. Effect of phenylephrine/ketorolac on iris fixation ring use and surgical times in patients at risk of intraoperative miosis

    Directory of Open Access Journals (Sweden)

    Visco D

    2018-02-01

    Full Text Available Denise Visco Eyes of York Cataract & Laser Center, York, PA, USA Purpose: To evaluate the effect of intracameral phenylephrine/ketorolac (1%/0.3% during cataract surgery on the use of iris fixation ring and surgical time in patients with poor pupil dilation (≤5.0 mm or intraoperative floppy iris syndrome (IFIS. Setting: Private practice outpatient surgical center. Design: This retrospective analysis was conducted from January 1, 2014 to October 7, 2015. Materials and methods: The use of iris fixation rings was evaluated in a retrospective analysis of 46 patients who underwent cataract surgery from January 1, 2014, to October 7, 2015, and who were identified before surgery to be at risk for intraoperative miosis. The qualifying factors were presurgical examination of pupil dilation ≤5.0 mm after being administered topical tropicamide 1% and phenylephrine 2.5% or history of IFIS during surgery in the fellow eye. All patients received a 2-day preoperative course of topical nonsteroidal anti-inflammatory drugs (NSAIDs and day-of-surgery preoperative dilation using topical cyclopentolate 1%, tropicamide 1%, and phenylephrine 10%. Phenylephrine/ketorolac 1%/0.3% (Omidria® or epinephrine 1:1,000 with sulfites was added to the ophthalmic irrigation solution and delivered intracamerally at the start of the procedure and throughout surgery. The use of iris fixation rings and surgical time for each patient were captured for each group. Results: Eighteen (50% of the patients in the epinephrine group and no patients in the phenylephrine/ketorolac group required iris fixation ring insertion to maintain pupil dilation or to control IFIS (p=0.0034. Mean surgical time was significantly shorter in the group of patients who received phenylephrine/ketorolac (p=0.0068. Conclusion: In this retrospective cohort analysis of patients with poorly dilated pupils and/or IFIS, the use of intracameral phenylephrine/ketorolac in patients at risk for intraoperative

  2. The Effects of Fatigue From Overnight Shifts on Radiology Search Patterns and Diagnostic Performance.

    Science.gov (United States)

    Hanna, Tarek N; Zygmont, Matthew E; Peterson, Ryan; Theriot, David; Shekhani, Haris; Johnson, Jamlik-Omari; Krupinski, Elizabeth A

    2018-01-20

    The aim of this study was to assess the effect of overnight shifts (ONS) on radiologist fatigue, visual search pattern, and diagnostic performance. This experimental study was approved by the institutional review board. Twelve radiologists (five faculty members and seven residents) each completed two sessions: one during a normal workday ("not fatigued") and another in the morning after an ONS ("fatigued"). Each radiologist completed the Swedish Occupational Fatigue Inventory. During each session, radiologists viewed 20 bone radiographs consisting of normal and abnormal findings. Viewing time, diagnostic confidence, and eye-tracking data were recorded. Swedish Occupational Fatigue Inventory results demonstrated worsening in all five variables (lack of energy, physical exertion, physical discomfort, lack of motivation, and sleepiness) after ONS (P radiologists were more fatigued with worse diagnostic performance, a 45% increase in view time per case, a 60% increase in total gaze fixations, and a 34% increase in time to fixate on the fracture. The effects of fatigue were more pronounced in residents. Copyright © 2017 American College of Radiology. Published by Elsevier Inc. All rights reserved.

  3. Anxiety symptoms and children's eye gaze during fear learning.

    Science.gov (United States)

    Michalska, Kalina J; Machlin, Laura; Moroney, Elizabeth; Lowet, Daniel S; Hettema, John M; Roberson-Nay, Roxann; Averbeck, Bruno B; Brotman, Melissa A; Nelson, Eric E; Leibenluft, Ellen; Pine, Daniel S

    2017-11-01

    The eye region of the face is particularly relevant for decoding threat-related signals, such as fear. However, it is unclear if gaze patterns to the eyes can be influenced by fear learning. Previous studies examining gaze patterns in adults find an association between anxiety and eye gaze avoidance, although no studies to date examine how associations between anxiety symptoms and eye-viewing patterns manifest in children. The current study examined the effects of learning and trait anxiety on eye gaze using a face-based fear conditioning task developed for use in children. Participants were 82 youth from a general population sample of twins (aged 9-13 years), exhibiting a range of anxiety symptoms. Participants underwent a fear conditioning paradigm where the conditioned stimuli (CS+) were two neutral faces, one of which was randomly selected to be paired with an aversive scream. Eye tracking, physiological, and subjective data were acquired. Children and parents reported their child's anxiety using the Screen for Child Anxiety Related Emotional Disorders. Conditioning influenced eye gaze patterns in that children looked longer and more frequently to the eye region of the CS+ than CS- face; this effect was present only during fear acquisition, not at baseline or extinction. Furthermore, consistent with past work in adults, anxiety symptoms were associated with eye gaze avoidance. Finally, gaze duration to the eye region mediated the effect of anxious traits on self-reported fear during acquisition. Anxiety symptoms in children relate to face-viewing strategies deployed in the context of a fear learning experiment. This relationship may inform attempts to understand the relationship between pediatric anxiety symptoms and learning. © 2017 Association for Child and Adolescent Mental Health.

  4. Eye movement control in reading unspaced text: the case of the Japanese script.

    Science.gov (United States)

    Kajii, N; Nazir, T A; Osaka, N

    2001-09-01

    The present study examines the landing-site distributions of the eyes during natural reading of Japanese script: a script that mixes three different writing systems (Kanji, Hiragana, and Katakana) and that misses regular spacing between words. The results show a clear preference of the eyes to land at the beginning rather than the center of the word. In addition, it was found that the eyes land on Kanji characters more frequently than on Hiragana or Katakana characters. Further analysis for two- and three-character words indicated that the eye's landing-site distribution differs depending on type of the characters in the word: the eyes prefer to land at the word beginning only when the initial character of the word is a Kanji character. For pure Hiragana words, the proportion of initial fixations did not differ between character positions. Thus, as already indicated by Kambe (National Institute of Japanese Language Report 85 (1986) 29), the visual distinctiveness of the three Japanese scripts plays a role in guiding eye movements in reading Japanese.

  5. The amblyopic eye in subjects with anisometropia show increased saccadic latency in the delayed saccade task

    Directory of Open Access Journals (Sweden)

    Maciej ePerdziak

    2014-10-01

    Full Text Available The term amblyopia is used to describe reduced visual function in one eye (or both eyes, though not so often which cannot be fully improved by refractive correction and explained by the organic cause observed during regular eye examination. This developmental disorder of spatial vision affects about 2-5% of the population and is associated with abnormal visual experience (e.g. anisometropia, strabismus during infancy or early childhood. Several studies have shown prolongation of saccadic latency time in amblyopic eye. In our opinion, study of saccadic latency in the context of central vision deficits assessment, should be based on central retina stimulation. For this reason, we proposed saccade delayed task. It requires inhibitory processing for maintaining fixation on the central target until it disappears – what constitutes the GO signal for saccade. The experiment consisted of 100 trials for each eye and was performed under two viewing conditions: monocular amblyopic / non-dominant eye and monocular dominant eye. We examined saccadic latency in 16 subjects (mean age 30±11 years with anisometropic amblyopia (two subjects had also microtropia and in 17 control subjects (mean age 28±8 years. Participants were instructed to look at central (fixation target and when it disappears, to make the saccade toward the periphery (10 deg as fast as possible, either left or the right target. The study results have proved the significant difference in saccadic latency between the amblyopic (mean 262±48 ms and dominant (mean 237±45 ms eye, in anisometropic group. In the control group, the saccadic latency for dominant (mean 226±32ms and non-dominant (mean 230±29 ms eye was not significantly different.By the use of LATER (Linear Approach to the Threshold with Ergodic Rate decision model we interpret our findings as a decrease in accumulation of visual information acquired by means of central (affected retina in subjects with anisometropic amblyopia.

  6. Comparison of skeletal stability after sagittal split ramus osteotomy among mono-cortical plate fixation, bi-cortical plate fixation, and hybrid fixation using absorbable plates and screws.

    Science.gov (United States)

    Ueki, Koichiro; Moroi, Akinori; Yoshizawa, Kunio; Hotta, Asami; Tsutsui, Takamitsu; Fukaya, Kenichi; Hiraide, Ryota; Takayama, Akihiro; Tsunoda, Tatsuta; Saito, Yuki

    2017-02-01

    The purpose of this study was to examine skeletal stability and plate breakage after sagittal split ramus osteotomy (SSRO) with the mono-cortical plate fixation, bi-cortical plate fixation, and hybrid fixation techniques using absorbable plates and screws. A total of 76 Japanese patients diagnosed with mandibular prognathism with and without maxillary deformity were divided into 3 groups randomly. A total of 28 patients underwent SSRO with mono-cortical plate fixation, 23 underwent SSRO with bi-cortical plate fixation, and 25 underwent SSRO with hybrid fixation. Skeletal stability and horizontal condylar angle were analyzed by axial, frontal, and lateral cephalograms from before the operation to 1 year postoperatively. Breakage of the plate and screws was observed by 3-dimensional computed tomography (3DCT) immediately after surgery and after 1 year. Although there was a significant difference between the mono-cortical plate fixation group and hybrid fixation group regarding right MeAg in T1 (P = 0.0488) and occlusal plane in T1 (P = 0.0346), there were no significant differences between the groups for the other measurements in each time interval. In 2 cases, namely, 6 sides in the mono-cortical plate fixation group, breakage of the absorbable plate was found by 3DCT. However, there was no breakage in the bi-cortical plate fixation group and hybrid fixation group. This study results suggested that there were no significant differences in the postoperative skeletal stability among the 3 groups, and bi-cortical fixation as well as hybrid fixation was a reliable and useful method to prevent plate breakage even if an absorbable material was used. Copyright © 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

  7. Pattern of Eye Diseases in Kaduna State – A rural community ...

    African Journals Online (AJOL)

    Senile cataract and anterior segment eye infection were the two eye diseases most frequently seen in Giwa community. The lack of trachoma seems to indicate that the rural water supplies were relatively clean and safe. The majority of eye problems were age-related, and preventable. Objective: The aim of the study was to ...

  8. MODELLING SYNERGISTIC EYE MOVEMENTS IN THE VISUAL FIELD

    Directory of Open Access Journals (Sweden)

    BARITZ Mihaela

    2015-06-01

    Full Text Available Some theoretical and practical considerations about eye movements in visual field are presented in the first part of this paper. These movements are developed into human body to be synergistic and are allowed to obtain the visual perception in 3D space. The theoretical background of the eye movements’ analysis is founded on the establishment of movement equations of the eyeball, as they consider it a solid body with a fixed point. The exterior actions, the order and execution of the movements are ensured by the neural and muscular external system and thus the position, stability and movements of the eye can be quantified through the method of reverse kinematic. The purpose of these researches is the development of a simulation model of human binocular visual system, an acquisition methodology and an experimental setup for data processing and recording regarding the eye movements, presented in the second part of the paper. The modeling system of ocular movements aims to establish the binocular synergy and limits of visual field changes in condition of ocular motor dysfunctions. By biomechanical movements of eyeball is established a modeling strategy for different sort of processes parameters like convergence, fixation and eye lens accommodation to obtain responses from binocular balance. The results of modelling processes and the positions of eye ball and axis in visual field are presented in the final part of the paper.

  9. Visual Processing of Faces in Individuals with Fragile X Syndrome: An Eye Tracking Study

    Science.gov (United States)

    Farzin, Faraz; Rivera, Susan M.; Hessl, David

    2009-01-01

    Gaze avoidance is a hallmark behavioral feature of fragile X syndrome (FXS), but little is known about whether abnormalities in the visual processing of faces, including disrupted autonomic reactivity, may underlie this behavior. Eye tracking was used to record fixations and pupil diameter while adolescents and young adults with FXS and sex- and…

  10. Guide to radiation fixatives

    International Nuclear Information System (INIS)

    Tawil, J.J.; Bold, F.C.

    1983-11-01

    This report identifies and then characterizes a variety of substances available in the market place for potential effectiveness as a fixative on radiologically contaminated surfaces. The substances include both generic chemicals and proprietary products. In selecting a fixative for a particular application, several attributes of the fixative may be relevant to the choice. These attributes include: toxicity, durability, and cleanliness and removability. In addition to the attributes of the fixative, one should also take into account certain characteristics of the site to be treated. These characteristics relate to climate, nature of the surface, use to which the treated surface will be put, subsequent cleanup operations, and type of neighboring surfaces. Finally, costs and potential environmental effects may influence the decision. A variety of fixatives are evaluated with respect to these various attributes and summarized in a reference table

  11. Ocular injuries and eye care seeking patterns following injuries among cocoa farmers in Ghana.

    Science.gov (United States)

    Bert, Boadi-Kusi Samuel; Rekha, Hansraj; Percy, Mashige Khathutshelo

    2016-03-01

    The work environment of cocoa farmers exposes them to several ocular hazards that predispose them to eye diseases and injuries. However, the extent of ocular injuries and health seeking patterns following these injuries are unknown among cocoa farmers in Ghana. To determine the prevalence of ocular injuries and health seeking behaviour following injury among cocoa farmers in Ghana. Five hundred and fifty six participants were recruited through simple random sampling using a multistage approach from four cocoa growing districts in Ghana. A structured questionnaire was used to collect relevant information such as demography, ocular hazards and injuries experienced. An ocular examination was also conducted to assess the eye health of the participants. Descriptive and regression statistics were used to analyze the data. The rate of ocular injuries was calculated by using the number of injuries reported that resulted in lost work time/days divided by the number of worker years at risk of injury (sum of years worked in cocoa farms for all the participants). The rate of ocular injuries was 11.3/1000 worker years (95% CI: 9.4 - 31) which led to lost work time of 37.3/1000 worker years (95% CI: 34.1 - 40.8). The major causes of ocular injury were plants/branches (n=73, 51.1%), chemicals (n=27, 18.9%), cocoa pod/husk (n=14, 9.8%) and occurred mostly during weeding, harvesting and chemical spraying. Few (n=34, 6.1%) participants reported the use of ocular protection. Fifty-five (38.5%) participants visited the local chemical shops, while 37 (25.9%) visited hospitals/clinics for ocular treatment of their injuries. There is a high rate of ocular injuries among cocoa farmers who make insufficient use of appropriate eye care services. There is the need for eye health education among cocoa farmers in Ghana.

  12. Vergence-mediated changes in the axis of eye rotation during the human vestibulo-ocular reflex can occur independent of eye position.

    Science.gov (United States)

    Migliaccio, Americo A; Cremer, Phillip D; Aw, Swee T; Halmagyi, G Michael; Curthoys, Ian S; Minor, Lloyd B; Todd, Michael J

    2003-07-01

    The aim of this study was to determine whether vergence-mediated changes in the axis of eye rotation in the human vestibulo-ocular reflex (VOR) would obey Listing's Law (normally associated with saccadic eye movements) independent of the initial eye position. We devised a paradigm for disassociating the saccadic velocity axis from eye position by presenting near and far targets that were centered with respect to one eye. We measured binocular 3-dimensional eye movements using search coils in ten normal subjects and 3-dimensional linear head acceleration using Optotrak in seven normal subjects. The stimuli consisted of passive, unpredictable, pitch head rotations with peak acceleration of approximately 2000 degrees /s(2 )and amplitude of approximately 20 degrees. During the pitch head rotation, each subject fixated straight ahead with one eye, whereas the other eye was adducted 4 degrees during far viewing (94 cm) and 25 degrees during near viewing (15 cm). Our data showed expected compensatory pitch rotations in both eyes, and a vergence-mediated horizontal rotation only in the adducting eye. In addition, during near viewing we observed torsional eye rotations not only in the adducting eye but also in the eye looking straight ahead. In the straight-ahead eye, the change in torsional eye velocity between near and far viewing, which began approximately 40 ms after the start of head rotation, was 10+/-6 degrees /s (mean +/- SD). This change in torsional eye velocity resulted in a 2.4+/-1.5 degrees axis tilt toward Listing's plane in that eye. In the adducting eye, the change in torsional eye velocity between near and far viewing was 16+/-6 degrees /s (mean +/- SD) and resulted in a 4.1+/-1.4 degrees axis tilt. The torsional eye velocities were conjugate and both eyes partially obeyed Listing's Law. The axis of eye rotation tilted in the direction of the line of sight by approximately one-third of the angle between the line of sight and a line orthogonal to Listing

  13. Determination of the most appropriate stress distribution by Finite Element Analysis in fixation with resorbable screws after Bilateral Sagittal Split Ramus Osteotomy surgery

    Directory of Open Access Journals (Sweden)

    Sarkarat F.

    2009-12-01

    Full Text Available "nBackground and Aim: Due to the complications associated with fixation by Titanium screws and plates in Bilateral Sagittal Split Ramus Osteotomy (BSSRO surgery, the use of resorbable polymers has been increasingly recommended. Since there are not enough studies on this issue, this study aimed to assess the most appropriate stress distribution in fixation with resorbable screws after BSSRO surgery by Fnite Element Analysis (FEA."nMaterials and Methods: This experimental study was performed on simulated human mandible using Ansys and Catia softwares. The osteotomy line was applied to the simulated model and experimental loads of 75, 135 and 600 N were respectively exerted according to the natural direction of occlusal force. The distribution pattern of stress was assessed and compared for fixation with one resorbable screw, two resorbable screws in vertical pattern, two resorbable screws in horizontal pattern, three resorbable screws in L pattern and three resorbable screws in inverted backward L pattern using Ansys software."nResults: Among the four simulated fixations, L pattern showed the highest primary stability. Two screws in vertical pattern were also associated with sufficient primary stability and less trauma and cost for patients. One screw did not provide enough stability under 600 N."nConclusion: Polymer-based resorbable screws (polyglycolic acid and D, L polylactide acid provided satisfactory primary stability in BSSRO surgery.

  14. Response mode, compatibility, and dual-processes in the evaluation of simple gambles: An eye-tracking investigation

    Directory of Open Access Journals (Sweden)

    Paul Slovic

    2012-07-01

    Full Text Available We employed simple gambles to investigate information processing in relation to the compatibility effect. Subjects should be more likely to engage in a deliberative thinking strategy when completing a pricing task rather than a rating task. We used eye-tracking methodology to measure information acquisition and processing in order to test the above hypothesis as well as to show that losses and alternatives with uncertain outcomes are more likely than gains and alternatives with sure outcomes to be processed through a deliberative thinking process. Results showed that pupil dilations, fixation duration and number of fixations increased when subjects evaluated the gambles with a pricing task. Additionally, the number of fixations increased as the gamble outcome became increasingly negative and when the outcome was uncertain (vs. sure. Fixations were also predictive of subjects' final evaluations of the gambles. We discuss our results in light of the cognitive processes underlying different response modes in economic preferences.

  15. Biomechanics of lumbar cortical screw-rod fixation versus pedicle screw-rod fixation with and without interbody support.

    Science.gov (United States)

    Perez-Orribo, Luis; Kalb, Samuel; Reyes, Phillip M; Chang, Steve W; Crawford, Neil R

    2013-04-15

    Seven different combinations of posterior screw fixation, with or without interbody support, were compared in vitro using nondestructive flexibility tests. To study the biomechanical behavior of a new cortical screw (CS) fixation construct relative to the traditional pedicle screw (PS) construct. The CS is an alternative to the PS for posterior fixation of the lumbar spine. The CS trajectory is more sagittally and cranially oriented than the PS, being anchored in the pars interarticularis. Like PS fixation, CS fixation uses interconnecting rods fastened with top-locking connectors. Stability after bilateral CS fixation was compared with stability after bilateral PS fixation in the setting of intact disc and with direct lateral interbody fixation (DLIF) or transforaminal lateral interbody fixation (TLIF) support. Standard nondestructive flexibility tests were performed in cadaveric lumbar specimens, allowing non-paired comparisons of specific conditions from 28 specimens (4 groups of 7) within a larger experiment of multiple hardware configurations. Condition tested and group from which results originated were as follows: (1) intact (all groups); (2) with L3-L4 bilateral PS-rods (group 1); (3) with bilateral CS-rods (group 2); (4) with DLIF (group 3); (5) with DLIF + CS-rods (group 4); (6) with DLIF + PS-rods (group 3); (7) with TLIF + CS-rods (group 2), and (8) with TLIF + PS-rods (group 2). To assess spinal stability, the mean range of motion, lax zone, and stiff zone at L3-L4 were compared during flexion-extension, lateral bending, and axial rotation. With intact disc, stability was equivalent after PS-rod and CS-rod fixation, except that PS-rod fixation was stiffer during axial rotation. With DLIF support, there was no significant difference in stability between PS-rod and CS-rod fixation. With TLIF support, PS-rod fixation was stiffer than CS-rod fixation during lateral bending. Bilateral CS-rod fixation provided about the same stability in cadaveric specimens

  16. One visual search, many memory searches: An eye-tracking investigation of hybrid search.

    Science.gov (United States)

    Drew, Trafton; Boettcher, Sage E P; Wolfe, Jeremy M

    2017-09-01

    Suppose you go to the supermarket with a shopping list of 10 items held in memory. Your shopping expedition can be seen as a combination of visual search and memory search. This is known as "hybrid search." There is a growing interest in understanding how hybrid search tasks are accomplished. We used eye tracking to examine how manipulating the number of possible targets (the memory set size [MSS]) changes how observers (Os) search. We found that dwell time on each distractor increased with MSS, suggesting a memory search was being executed each time a new distractor was fixated. Meanwhile, although the rate of refixation increased with MSS, it was not nearly enough to suggest a strategy that involves repeatedly searching visual space for subgroups of the target set. These data provide a clear demonstration that hybrid search tasks are carried out via a "one visual search, many memory searches" heuristic in which Os examine items in the visual array once with a very low rate of refixations. For each item selected, Os activate a memory search that produces logarithmic response time increases with increased MSS. Furthermore, the percentage of distractors fixated was strongly modulated by the MSS: More items in the MSS led to a higher percentage of fixated distractors. Searching for more potential targets appears to significantly alter how Os approach the task, ultimately resulting in more eye movements and longer response times.

  17. Eye tracking measures of uncertainty during perceptual decision making.

    Science.gov (United States)

    Brunyé, Tad T; Gardony, Aaron L

    2017-10-01

    Perceptual decision making involves gathering and interpreting sensory information to effectively categorize the world and inform behavior. For instance, a radiologist distinguishing the presence versus absence of a tumor, or a luggage screener categorizing objects as threatening or non-threatening. In many cases, sensory information is not sufficient to reliably disambiguate the nature of a stimulus, and resulting decisions are done under conditions of uncertainty. The present study asked whether several oculomotor metrics might prove sensitive to transient states of uncertainty during perceptual decision making. Participants viewed images with varying visual clarity and were asked to categorize them as faces or houses, and rate the certainty of their decisions, while we used eye tracking to monitor fixations, saccades, blinks, and pupil diameter. Results demonstrated that decision certainty influenced several oculomotor variables, including fixation frequency and duration, the frequency, peak velocity, and amplitude of saccades, and phasic pupil diameter. Whereas most measures tended to change linearly along with decision certainty, pupil diameter revealed more nuanced and dynamic information about the time course of perceptual decision making. Together, results demonstrate robust alterations in eye movement behavior as a function of decision certainty and attention demands, and suggest that monitoring oculomotor variables during applied task performance may prove valuable for identifying and remediating transient states of uncertainty. Published by Elsevier B.V.

  18. An Exploration of Eye Movements when Reading Texts with Atypical Spatial Layouts

    Directory of Open Access Journals (Sweden)

    F Hermens

    2012-07-01

    Full Text Available In two experiments we explored eye movements that people make when looking at texts with an atypical spatial layout. In the first experiment, participants repeatedly viewed the same piece of text, containing sections in different languages and printed using different fonts and reading directions, while they answered different questions about what they saw. In agreement with earlier studies showing significant differences in gaze patterns across different tasks, we found that reading was strongly influenced by the questions that participants tried to answer. In the second experiment, we examined gaze patterns for different types of poems while participants performed a single task: To rate their appreciation of the poem. Poems were either in the typical form, with short lines all aligned to the left, or they were in an atypical form (“graphical poem”, with the text dispersed across the page, in different fonts, reading directions, and size. Half of the poems were from an artist known for his graphical poems, the other half were from different authors who posted their poems on a webpage. All these poems were presented in a typical and an atypical form. Participants rated the poems from the web more highly, but took less time to inspect them. Whether the poem was in a typical or an atypical layout did not influence the ratings, even though longer inspection times were found for the atypical forms. Eye movement parameters, such as fixation duration and saccade amplitude, were relatively unaffected by the layout of the poems, although some additional larger amplitude saccades could be observed for the atypical forms.

  19. An ocular biomechanic model for dynamic simulation of different eye movements.

    Science.gov (United States)

    Iskander, J; Hossny, M; Nahavandi, S; Del Porto, L

    2018-04-11

    Simulating and analysing eye movement is useful for assessing visual system contribution to discomfort with respect to body movements, especially in virtual environments where simulation sickness might occur. It can also be used in the design of eye prosthesis or humanoid robot eye. In this paper, we present two biomechanic ocular models that are easily integrated into the available musculoskeletal models. The model was previously used to simulate eye-head coordination. The models are used to simulate and analyse eye movements. The proposed models are based on physiological and kinematic properties of the human eye. They incorporate an eye-globe, orbital suspension tissues and six muscles with their connective tissues (pulleys). Pulleys were incorporated in rectus and inferior oblique muscles. The two proposed models are the passive pulleys and the active pulleys models. Dynamic simulations of different eye movements, including fixation, saccade and smooth pursuit, are performed to validate both models. The resultant force-length curves of the models were similar to the experimental data. The simulation results show that the proposed models are suitable to generate eye movement simulations with results comparable to other musculoskeletal models. The maximum kinematic root mean square error (RMSE) is 5.68° and 4.35° for the passive and active pulley models, respectively. The analysis of the muscle forces showed realistic muscle activation with increased muscle synergy in the active pulley model. Copyright © 2018 Elsevier Ltd. All rights reserved.

  20. Scleral Fixation of Posteriorly Dislocated Intraocular Lenses by 23-Gauge Vitrectomy without Anterior Segment Approach

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    Jeroni Nadal

    2015-01-01

    Full Text Available Background. To evaluate visual outcomes, corneal changes, intraocular lens (IOL stability, and complications after repositioning posteriorly dislocated IOLs and sulcus fixation with polyester sutures. Design. Prospective consecutive case series. Setting. Institut Universitari Barraquer. Participants. 25 eyes of 25 patients with posteriorly dislocated IOL. Methods. The patients underwent 23-gauge vitrectomy via the sulcus to rescue dislocated IOLs and fix them to the scleral wall with a previously looped nonabsorbable polyester suture. Main Outcome Measures. Best corrected visual acuity (BCVA LogMAR, corneal astigmatism, endothelial cell count, IOL stability, and postoperative complications. Results. Mean follow-up time was 18.8 ± 10.9 months. Mean surgery time was 33 ± 2 minutes. Mean BCVA improved from 0.30 ± 0.48 before surgery to 0.18 ± 0.60 (p=0.015 at 1 month, which persisted to 12 months (0.18 ± 0.60. Neither corneal astigmatism nor endothelial cell count showed alterations 1 year after surgery. Complications included IOL subluxation in 1 eye (4%, vitreous hemorrhage in 2 eyes (8%, transient hypotony in 2 eyes (8%, and cystic macular edema in 1 eye (4%. No patients presented retinal detachment. Conclusion. This surgical technique proved successful in the management of dislocated IOL. Functional results were good and the complications were easily resolved.

  1. Scleral Fixation of Posteriorly Dislocated Intraocular Lenses by 23-Gauge Vitrectomy without Anterior Segment Approach.

    Science.gov (United States)

    Nadal, Jeroni; Kudsieh, Bachar; Casaroli-Marano, Ricardo P

    2015-01-01

    Background. To evaluate visual outcomes, corneal changes, intraocular lens (IOL) stability, and complications after repositioning posteriorly dislocated IOLs and sulcus fixation with polyester sutures. Design. Prospective consecutive case series. Setting. Institut Universitari Barraquer. Participants. 25 eyes of 25 patients with posteriorly dislocated IOL. Methods. The patients underwent 23-gauge vitrectomy via the sulcus to rescue dislocated IOLs and fix them to the scleral wall with a previously looped nonabsorbable polyester suture. Main Outcome Measures. Best corrected visual acuity (BCVA) LogMAR, corneal astigmatism, endothelial cell count, IOL stability, and postoperative complications. Results. Mean follow-up time was 18.8 ± 10.9 months. Mean surgery time was 33 ± 2 minutes. Mean BCVA improved from 0.30 ± 0.48 before surgery to 0.18 ± 0.60 (p = 0.015) at 1 month, which persisted to 12 months (0.18 ± 0.60). Neither corneal astigmatism nor endothelial cell count showed alterations 1 year after surgery. Complications included IOL subluxation in 1 eye (4%), vitreous hemorrhage in 2 eyes (8%), transient hypotony in 2 eyes (8%), and cystic macular edema in 1 eye (4%). No patients presented retinal detachment. Conclusion. This surgical technique proved successful in the management of dislocated IOL. Functional results were good and the complications were easily resolved.

  2. Results of application of external fixation with different types of fixators

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    Grubor Predrag

    2012-01-01

    Full Text Available Introduction. Extra-focal or external fixation is the method of fracture fixation through the healthy part of the bone using pins or wires. Objective. The aim was to determine which external splints (Ortofix, Mitković, Charnley and Ilizarov had the best biomechanical properties in primary stabilization of spiral, transverse and commutative bone fractures. Methods. To determine the investigation methodology of biomechanical characteristics of the external fixator we used mathematical and computer simulator (software, juvidur physical model and clinical examination. Results. Values of advancing fragments in millimetres obtained by the study of mathematical and computer simulator (software: Charnley - 0.080 mm, Mitković M 20 - 0.785 mm, Ilizarov - 2.245 mm and Ortofix - 1.400 mm. In testing the juvidur model the following values were obtained: the external fixator Mitković M20 - 1.380 mm, Ortofix - 1.470 mm, Ilizarov - 2.410 mm, and Charnley - 2.510 mm. Clinical research of biomechanical characteristics of the effect of vertical force yielded the following results: Mitković M20 - 0.89 mm, Ortofix - 0.14 mm, Charnley - 0.80 mm and Ilizarov - 1.23 mm. Conclusion. When determining the total number of the stability test splints under the effect of vertical force (compression and force effect in antero-posterior, later-lateral plane of cross, spiral and comminuted long bone fractures, the best unified biomechanical stability was shown by the following external fixators: firstly, Mitković M20 (0.93mm, secondly, Charnley fixator (1.14 mm, thirdly, Ortofix (1.22 mm, and fourthly, Ilizarov (1.60 mm.

  3. Patterns of Eye Diseases in Children Visiting a Tertiary Teaching ...

    African Journals Online (AJOL)

    Background: About 19 million children worldwide live with visual impairments resulting from different ocular morbidities. This study aimed to identify the different causes of eye diseases in children visiting a tertiary eye centre at Jimma University Hospital. Methods: We conducted a retrospective review of charts of patients of ...

  4. Eye-Tracking Study on Facial Emotion Recognition Tasks in Individuals with High-Functioning Autism Spectrum Disorders

    Science.gov (United States)

    Tsang, Vicky

    2018-01-01

    The eye-tracking experiment was carried out to assess fixation duration and scan paths that individuals with and without high-functioning autism spectrum disorders employed when identifying simple and complex emotions. Participants viewed human photos of facial expressions and decided on the identification of emotion, the negative-positive emotion…

  5. Fixation strength of a polyetheretherketone femoral component in total knee arthroplasty.

    Science.gov (United States)

    de Ruiter, Lennert; Janssen, Dennis; Briscoe, Adam; Verdonschot, Nico

    2017-11-01

    Introducing polyetheretherketone (PEEK) polymer as a material for femoral components in total knee arthroplasty (TKA) could potentially lead to a reduction of the cemented fixation strength. A PEEK implant is more likely to deform under high loads, rendering geometrical locking features less effective. Fixation strength may be enhanced by adding more undercuts or specific surface treatments. The aim of this study is to measure the initial fixation strength and investigate the associated failure patterns of three different iterations of PEEK-OPTIMA ® implants compared with a Cobalt-Chromium (CoCr) component. Femoral components were cemented onto trabecular bone analogue foam blocks and preconditioned with 86,400 cycles of compressive loading (2600 N-260 N at 1 Hz). They were then extracted while the force was measured and the initial failure mechanism was recorded. Four groups were compared: CoCr, regular PEEK, PEEK with an enhanced cement-bonding surface and the latter with additional surface primer. The mean pull-off forces for the four groups were 3814 N, 688 N, 2525 N and 2552 N, respectively. The initial failure patterns for groups 1, 3 and 4 were the same; posterior condylar foam fracture and cement-bone debonding. Implants from group 2 failed at the cement-implant interface. This study has shown that a PEEK-OPTIMA ® femoral TKA component with enhanced macro- and microtexture is able to replicate the main failure mechanism of a conventional CoCr femoral implant. The fixation strength is lower than for a CoCr implant, but substantially higher than loads occurring under in-vivo conditions. Copyright © 2017 IPEM. Published by Elsevier Ltd. All rights reserved.

  6. Object detection via eye tracking and fringe restraint

    Science.gov (United States)

    Pan, Fei; Zhang, Hanming; Zeng, Ying; Tong, Li; Yan, Bin

    2017-07-01

    Object detection is a computer vision problem which caught a large amount of attention. But the candidate boundingboxes extracted from only image features may end up with false-detection due to the semantic gap between the top-down and the bottom up information. In this paper, we propose a novel method for generating object bounding-boxes proposals using the combination of eye fixation point, saliency detection and edges. The new method obtains a fixation orientated Gaussian map, optimizes the map through single-layer cellular automata, and derives bounding-boxes from the optimized map on three levels. Then we score the boxes by combining all the information above, and choose the box with the highest score to be the final box. We perform an evaluation of our method by comparing with previous state-ofthe art approaches on the challenging POET datasets, the images of which are chosen from PASCAL VOC 2012. Our method outperforms them on small scale objects while comparable to them in general.

  7. Attentional Modulation of Eye Torsion Responses

    Science.gov (United States)

    Stevenson, Scott B.; Mahadevan, Madhumitha S.; Mulligan, Jeffrey B.

    2016-01-01

    Eye movements generally have both reflexive and voluntary aspects, but torsional eye movements are usually thought of as a reflexive response to image rotation around the line of sight (torsional OKN) or to head roll (torsional VOR). In this study we asked whether torsional responses could be modulated by attention in a case where two stimuli rotated independently, and whether attention would influence the latency of responses. The display consisted of rear-projected radial "pinwheel" gratings, with an inner annulus segment extending from the center to 22 degrees eccentricity, and an outer annulus segment extending from 22 degrees out to 45 degrees eccentricity. The two segments rotated around the center in independent random walks, stepping randomly 4 degrees clockwise or counterclockwise at 60 Hz. Subjects were asked to attend to one or the other while keeping fixation steady at the center of the display. To encourage attention on one or the other segment of the display, subjects were asked to move a joystick in synchrony with the back and forth rotations of one part of the image while ignoring the other. Eye torsion was recorded with the scleral search coil technique, sampled at 500 Hz. All four subjects showed roughly 50% stronger torsion responses to the attended compared to unattended segments. Latency varied from 100 to 150 msec across subjects and was unchanged by attention. These findings suggest that attention can influence eye movement responses that are not typically under voluntary control.

  8. Pattern of eye diseases among welders in a Nigeria community ...

    African Journals Online (AJOL)

    Background: Welders have been identified as a high risk group for eye disorders due to their exposure to ultraviolet radiation. Objective: To determine the prevalence and types of eye diseases amongst welders in Ile-Ife, Osun state. Methods: This is a cross sectional descriptive study of 405 consenting welders. Information ...

  9. Integrating Click-Through and Eye-Tracking Logs for Decision-Making Process Mining

    Directory of Open Access Journals (Sweden)

    Razvan PETRUSEL

    2014-01-01

    Full Text Available In current software every click of the users is logged, therefore a wealth of click-through information exists. Besides, recent technologies have made eye-tracking affordable and an alternative to other human-computer interaction means (e.g. mouse, touchscreens. A big challenge is to make sense of all this data and convert it into useful information. This paper introduces a possible solution placed in the context of decision-making processes. We show how the decision maker's activity can be traced using two means: mouse tracing (i.e. clicks and eye-tracking (i.e. eye fixations. Then, we discuss a mining approach, based on the log, which extracts a Decision Data Model (DDM. We use the DDM to determine, post-hoc, which decision strategy was employed. The paper concludes with a validation based on a controlled experiment.

  10. Management of digital eye strain.

    Science.gov (United States)

    Coles-Brennan, Chantal; Sulley, Anna; Young, Graeme

    2018-05-23

    Digital eye strain, an emerging public health issue, is a condition characterised by visual disturbance and/or ocular discomfort related to the use of digital devices and resulting from a range of stresses on the ocular environment. This review aims to provide an overview of the extensive literature on digital eye strain research with particular reference to the clinical management of symptoms. As many as 90 per cent of digital device users experience symptoms of digital eye strain. Many studies suggest that the following factors are associated with digital eye strain: uncorrected refractive error (including presbyopia), accommodative and vergence anomalies, altered blinking pattern (reduced rate and incomplete blinking), excessive exposure to intense light, closer working distance, and smaller font size. Since a symptom may be caused by one or more factors, a holistic approach should be adopted. The following management strategies have been suggested: (i) appropriate correction of refractive error, including astigmatism and presbyopia; (ii) management of vergence anomalies, with the aim of inducing or leaving a small amount of heterophoria (~1.5 Δ Exo); (iii) blinking exercise/training to maintain normal blinking pattern; (iv) use of lubricating eye drops (artificial tears) to help alleviate dry eye-related symptoms; (v) contact lenses with enhanced comfort, particularly at end-of-day and in challenging environments; (vi) prescription of colour filters in all vision correction options, especially blue light-absorbing filters; and (vii) management of accommodative anomalies. Prevention is the main strategy for management of digital eye strain, which involves: (i) ensuring an ergonomic work environment and practice (through patient education and the implementation of ergonomic workplace policies); and (ii) visual examination and eye care to treat visual disorders. Special consideration is needed for people at a high risk of digital eye strain, such as computer

  11. Time course Analysis of Gene expression patterns in ZebrafIsh Eye during Optic Nerve Regeneration

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    Amy T. Mccurley

    2010-01-01

    Full Text Available It is well-established that neurons in the adult mammalian central nervous system (CNS are terminally differentiated and, if injured, will be unable to regenerate their connections. In contrast to mammals, zebrafish and other teleosts display a robust neuroregenerative response. Following optic nerve crush (ONX, retinal ganglion cells (RGC regrow their axons to synapse with topographically correct targets in the optic tectum, such that vision is restored in ~21 days. What accounts for these differences between teleostean and mammalian responses to neural injury is not fully understood. A time course analysis of global gene expression patterns in the zebrafish eye after ONX can help to elucidate cellular and molecular mechanisms that contribute to a successful neuroregeneration. To define different phases of regeneration after ONX, alpha tubulin 1 ( tuba1 and growth-associated protein 43 ( gap43 , markers previously shown to correspond to morphophological events, were measured by real time quantitative PCR (qPCR. Microarray analysis was then performed at defined intervals (6 hours, 1, 4, 12, and 21 days post-ONX and compared to SHAM. Results show that optic nerve damage induces multiple, phase-related transcriptional programs, with the maximum number of genes changed and highest fold-change occurring at 4 days. Several functional groups affected by optic nerve regeneration, including cell adhesion, apoptosis, cell cycle, energy metabolism, ion channel activity, and calcium signaling, were identified. Utilizing the whole eye allowed us to identify signaling contributions from the vitreous, immune and glial cells as well as the neural cells of the retina. Comparisons between our dataset and transcriptional profiles from other models of regeneration in zebrafish retina, heart and fin revealed a subset of commonly regulated transcripts, indicating shared mechanisms in different regenerating tissues. Knowledge of gene expression patterns in all

  12. Subluxation of suture-fixated posterior chamber intraocular lenses a clinicopathologic study.

    Science.gov (United States)

    Parekh, Parag; Green, W Richard; Stark, Walter J; Akpek, Esen Karamursel

    2007-02-01

    To report the occurrence of subluxation of suture-fixated posterior chamber (PC) intraocular lenses (IOL) and elucidate the mechanisms involved. Prospective clinicopathologic study. A single 10-0 Prolene suture explanted from a patient who experienced subluxation of his PC-IOL, 11.5 years after placement. Furthermore, multiple 10-0 Prolene sutures and PC-IOLs used for iris fixation were studied as controls. Scanning electron microscopy (SEM) was used to analyze the surface of the explanted suture. In addition, randomly selected 10-0 Prolene sutures cut with Vannas scissors and cut with the positioning holes of a randomly selected PC-IOL identical to that implanted in the patient's eye were examined as controls. Finally, the positioning holes of several randomly selected, iris-fixated PC-IOLs were studied using SEM with particular attention to surface quality and edge finish. Presence of any signs of suture degradation, the character of the cut edge of the suture, as well as the characteristics of the positioning holes of the PC-IOLs. Scanning electron microscopy of the explanted suture revealed sharply cut edges, without significant degradation of the suture, and no intact loop. Scanning electron microscopy of the control suture cut with a PC-IOL demonstrated a similarly cut edge. The positioning holes of the examined PC-IOLs had a sharp edge, and some also had an imperfect finish. We conclude that the surface properties of the positioning holes lead to cutting of the suture, and subsequent subluxation of the PC-IOL.

  13. Children’s Empathy and Their Perception and Evaluation of Facial Pain Expression: An Eye Tracking Study

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    Zhiqiang Yan

    2017-12-01

    Full Text Available The function of empathic concern to process pain is a product of evolutionary adaptation. Focusing on 5- to 6-year old children, the current study employed eye-tracking in an odd-one-out task (searching for the emotional facial expression among neutral expressions, N = 47 and a pain evaluation task (evaluating the pain intensity of a facial expression, N = 42 to investigate the relationship between children’s empathy and their behavioral and perceptual response to facial pain expression. We found children detected painful expression faster than others (angry, sad, and happy, children high in empathy performed better on searching facial expression of pain, and gave higher evaluation of pain intensity; and rating for pain in painful expressions was best predicted by a self-reported empathy score. As for eye-tracking in pain detection, children fixated on pain more quickly, less frequently and for shorter times. Of facial clues, children fixated on eyes and mouth more quickly, more frequently and for longer times. These results implied that painful facial expression was different from others in a cognitive sense, and children’s empathy might facilitate their search and make them perceive the intensity of observed pain on the higher side.

  14. Analysis of exploratory eye movements in patients with schizophrenia during visual scanning of projective tests' figures Análise dos movimentos oculares de pacientes com esquizofrenia durante a exploração visual de figuras de testes projetivos

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    Katerina Lukasova

    2010-01-01

    Full Text Available OBJECTIVE: Compare pattern of exploratory eye movements during visual scanning of the Rorschach and TAT test cards in people with schizophrenia and controls. METHOD: 10 participants with schizophrenia and 10 controls matched by age, schooling and intellectual level participated in the study. Severity of symptoms was evaluated with the Positive and Negative Syndrome Scale. Test cards were divided into three groups: TAT cards with scenes content, TAT cards with interaction content (TAT-faces, and Rorschach cards with abstract images. Eye movements were analyzed for: total number, duration and location of fixation; and length of saccadic movements. RESULTS: Different pattern of eye movement was found, with schizophrenia participants showing lower number of fixations but longer fixation duration in Rorschach cards and TAT-faces. The biggest difference was observed in Rorschach, followed by TAT-faces and TAT-scene cards. CONCLUSIONS: Results suggest alteration in visual exploration mechanisms possibly related to integration of abstract visual information.OBJETIVO: Comparar o padrão do movimento ocular durante a inspeção dos cartões dos testes projetivos Rorschach e TAT em pessoas com esquizofrenia e controles. MÉTODO: Participaram 10 sujeitos com esquizofrenia e 10 controles, pareados por idade, escolaridade e nível de inteligência. A severidade dos sintomas foi avaliada com a Escala das Síndromes Positiva e Negativa. Os cartões dos testes foram divididos em três grupos: figuras do TAT representando ambientes, figuras do TAT com faces humanas e figuras abstratas do teste Rorschach. Os movimentos oculares foram analisados para: número total, duração e localização das fixações e comprimento dos movimentos sacádicos. RESULTADOS: Foram encontradas diferenças no padrão do movimento ocular, e pessoas com esquizofrenia apresentaram menos fixações nos cartões do teste Rorschach e TAT-faces. Maiores diferenças foram observadas nos cart

  15. Eye gaze tracking based on the shape of pupil image

    Science.gov (United States)

    Wang, Rui; Qiu, Jian; Luo, Kaiqing; Peng, Li; Han, Peng

    2018-01-01

    Eye tracker is an important instrument for research in psychology, widely used in attention, visual perception, reading and other fields of research. Because of its potential function in human-computer interaction, the eye gaze tracking has already been a topic of research in many fields over the last decades. Nowadays, with the development of technology, non-intrusive methods are more and more welcomed. In this paper, we will present a method based on the shape of pupil image to estimate the gaze point of human eyes without any other intrusive devices such as a hat, a pair of glasses and so on. After using the ellipse fitting algorithm to deal with the pupil image we get, we can determine the direction of the fixation by the shape of the pupil.The innovative aspect of this method is to utilize the new idea of the shape of the pupil so that we can avoid much complicated algorithm. The performance proposed is very helpful for the study of eye gaze tracking, which just needs one camera without infrared light to know the changes in the shape of the pupil to determine the direction of the eye gazing, no additional condition is required.

  16. The geometric preference subtype in ASD: identifying a consistent, early-emerging phenomenon through eye tracking.

    Science.gov (United States)

    Moore, Adrienne; Wozniak, Madeline; Yousef, Andrew; Barnes, Cindy Carter; Cha, Debra; Courchesne, Eric; Pierce, Karen

    2018-01-01

    The wide range of ability and disability in ASD creates a need for tools that parse the phenotypic heterogeneity into meaningful subtypes. Using eye tracking, our past studies revealed that when presented with social and geometric images, a subset of ASD toddlers preferred viewing geometric images, and these toddlers also had greater symptom severity than ASD toddlers with greater social attention. This study tests whether this "GeoPref test" effect would generalize across different social stimuli. Two hundred and twenty-seven toddlers (76 ASD) watched a 90-s video, the Complex Social GeoPref test, of dynamic geometric images paired with social images of children interacting and moving. Proportion of visual fixation time and number of saccades per second to both images were calculated. To allow for cross-paradigm comparisons, a subset of 126 toddlers also participated in the original GeoPref test. Measures of cognitive and social functioning (MSEL, ADOS, VABS) were collected and related to eye tracking data. To examine utility as a diagnostic indicator to detect ASD toddlers, validation statistics (e.g., sensitivity, specificity, ROC, AUC) were calculated for the Complex Social GeoPref test alone and when combined with the original GeoPref test. ASD toddlers spent a significantly greater amount of time viewing geometric images than any other diagnostic group. Fixation patterns from ASD toddlers who participated in both tests revealed a significant correlation, supporting the idea that these tests identify a phenotypically meaningful ASD subgroup. Combined use of both original and Complex Social GeoPref tests identified a subgroup of about 1 in 3 ASD toddlers from the "GeoPref" subtype (sensitivity 35%, specificity 94%, AUC 0.75.) Replicating our previous studies, more time looking at geometric images was associated with significantly greater ADOS symptom severity. Regardless of the complexity of the social images used (low in the original GeoPref test vs high in

  17. [Complications of open reduction and internal fixation versus external fixation for unstable distal radius fractures: a meta-analysis].

    Science.gov (United States)

    Yang, Z; Yuan, Z Z; Ma, J X; Ma, X L

    2016-12-20

    Objective: To make a systematic assessment of the complications of open reduction and internal fixation versus external fixation for unstable distal radius fractures. Method: A computer-based online search of PubMed, ScienceDirect, EMBASE, BIOSIS, Springer and Cochrane Library were performed.The randomized and controlled trials of open reduction and internal fixation versus external fixation for unstable distal radius fractures were collected.The included trials were screened out strictly based on the criterion of inclusion and exclusion.The quality of included trials was evaluated.RevMan 5.0 was used for data analysis. Result: A total of 17 studies involving 1 402 patients were included.There were 687 patients with open reduction and internal fixation and 715 with external fixation.The results of Meta-analysis indicated that there were statistically significant differences with regard to the postoperatively total complications, infection, malunion, tendon rupture ( I 2 =8%, RR =0.77(95% CI 0.65-0.91, Z =3.10, P 0.05). Conclusion: Postoperative complications are present in both open reduction and internal fixation and external fixation.Compared with external fixation, open reduction and internal fixation is lower in total complications postoperatively, infection and malunion, but external fixation has lower tendon rupture incidence.

  18. Effectiveness of external fixator combined with T-plate internal fixation for the treatment of comminuted distal radius fractures.

    Science.gov (United States)

    Han, L R; Jin, C X; Yan, J; Han, S Z; He, X B; Yang, X F

    2015-03-31

    This study compared the efficacy between external fixator combined with palmar T-plate internal fixation and simple plate internal fixation for the treatment of comminuted distal radius fractures. A total of 61 patients classified as type C according to the AO/ASIF classification underwent surgery for comminuted distal radius fractures. There were 54 and 7 cases of closed and open fractures, respectively. Moreover, 19 patients received an external fixator combined with T-plate internal fixation, and 42 received simple plate internal fixation. All patients were treated successfully during 12-month postoperative follow-up. The follow-up results show that the palmar flexion and dorsiflexion of the wrist, radial height, and palmar angle were significantly better in those treated with the external fixator combined with T-plate compared to those treated with the simple plate only (P 0.05). Hence, the effectiveness of external fixator combined with T-plate internal fixation for the treatment of comminuted distal radius fractures was satisfactory. Patients sufficiently recovered wrist, forearm, and hand function. In conclusion, compared to the simple T-plate, the external fixator combined with T-plate internal fixation can reduce the possibility of the postoperative re-shifting of broken bones and keep the distraction of fractures to maintain radial height and prevent radial shortening.

  19. The Nine-Step Minnesota Grading System for Eyebank Eyes With Age Related Macular Degeneration: A Systematic Approach to Study Disease Stages.

    Science.gov (United States)

    Olsen, Timothy W; Liao, Albert; Robinson, Hershonna S; Palejwala, Neal V; Sprehe, Nicholas

    2017-10-01

    To refine the Minnesota Grading System (MGS) using definitions from the Age-Related Eye Disease Studies (AREDS) into a nine-step grading scale (MGS-9). A nine-step grading scale descriptive analysis using three key phenotypic features (total drusen area, increased, and decreased pigmentation) of human eyebank eyes that were graded according to definitions from the AREDS criteria in order to harmonize studies of disease progression for research involving human tissue. From 2005 through February 2017, we have analyzed 1159 human eyes, procured from two eyebanks. Each macula was imaged using high-resolution, stereoscopic color fundus photography with both direct- and transillumination. Fundus images were digitally overlaid with a grading template and triangulated for foveal centration. We documented and stratified risk for each globe by applying the AREDS nine-step grading scale to the key clinical features from the MGS-9. We found a good distribution within the MGS categories (1-9) with few level eight globes. Eyes were processed within 12.1 ± 6.3, hours from the time of death through imaging, dissection, and freezing or fixation. Applying the MGS-9 to 331 pairs (662 eyes were simultaneously graded), 84% were within one-grading step and 93% within two steps of the fellow eye. We also document reticular pseudodrusen, basal laminar drusen, and pattern dystrophy. The MGS nine-step grading scale enables researchers using human tissue to refine the risk assessment of donor tissue. This analysis will harmonize results among researchers when grading human tissue using MGS criteria. Most importantly, the MGS-9 links directly to the known risk for progression from the AREDS.

  20. Eye Movement Control in Scene Viewing and Reading: Evidence from the Stimulus Onset Delay Paradigm

    Science.gov (United States)

    Luke, Steven G.; Nuthmann, Antje; Henderson, John M.

    2013-01-01

    The present study used the stimulus onset delay paradigm to investigate eye movement control in reading and in scene viewing in a within-participants design. Short onset delays (0, 25, 50, 200, and 350 ms) were chosen to simulate the type of natural processing difficulty encountered in reading and scene viewing. Fixation duration increased…

  1. Social exclusion leads to attentional bias to emotional social information: Evidence from eye movement.

    Science.gov (United States)

    Chen, Zhuohao; Du, Jinchen; Xiang, Min; Zhang, Yan; Zhang, Shuyue

    2017-01-01

    Social exclusion has many effects on individuals, including the increased need to belong and elevated sensitivity to social information. Using a self-reporting method, and an eye-tracking technique, this study explored people's need to belong and attentional bias towards the socio-emotional information (pictures of positive and negative facial expressions compared to those of emotionally-neutral expressions) after experiencing a brief episode of social exclusion. We found that: (1) socially-excluded individuals reported higher negative emotions, lower positive emotions, and stronger need to belong than those who were not socially excluded; (2) compared to a control condition, social exclusion caused a longer response time to probe dots after viewing positive or negative face images; (3) social exclusion resulted in a higher frequency ratio of first attentional fixation on both positive and negative emotional facial pictures (but not on the neutral pictures) than the control condition; (4) in the social exclusion condition, participants showed shorter first fixation latency and longer first fixation duration to positive pictures than neutral ones but this effect was not observed for negative pictures; (5) participants who experienced social exclusion also showed longer gazing duration on the positive pictures than those who did not; although group differences also existed for the negative pictures, the gaze duration bias from both groups showed no difference from chance. This study demonstrated the emotional response to social exclusion as well as characterising multiple eye-movement indicators of attentional bias after experiencing social exclusion.

  2. Modeling the impact of iron and phosphorus limitations on nitrogen fixation in the Atlantic Ocean

    Directory of Open Access Journals (Sweden)

    R. R. Hood

    2007-07-01

    Full Text Available The overarching goal of this study is to simulate subsurface N* (sensu, Gruber and Sarmiento, 1997; GS97 anomaly patterns in the North Atlantic Ocean and determine the basin wide rates of N2-fixation that are required to do so. We present results from a new Atlantic implementation of a coupled physical-biogeochemical model that includes an explicit, dynamic representation of N2-fixation with light, nitrogen, phosphorus and iron limitations, and variable stoichiometric ratios. The model is able to reproduce nitrogen, phosphorus and iron concentration variability to first order. The latter is achieved by incorporating iron deposition directly into the model's detrital iron compartment which allows the model to reproduce sharp near surface gradients in dissolved iron concentration off the west coast of Africa and deep dissolved iron concentrations that have been observed in recent observational studies. The model can reproduce the large scale N* anomaly patterns but requires relatively high rates of surface nitrogen fixation to do so (1.8×1012 moles N yr−1 from 10° N–30° N, 3.4×1012 moles N yr−1 from 25° S–65° N. In the model the surface nitrogen fixation rate patterns are not co-located with subsurface gradients in N*. Rather, the fixed nitrogen is advected away from its source prior to generating a subsurface N* anomaly. Changes in the phosphorus remineralization rate (relative to nitrogen linearly determine the surface nitrogen fixation rate because they change the degree of phosphorus limitation, which is the dominant limitation in the Atlantic in the model. Phosphorus remineralization rate must be increased by about a factor of 2 (relative to nitrogen in order to generate subsurface N* anomalies that are comparable to the observations. We conclude that N2-fixation rate estimates for the Atlantic (and globally may need to be revised upward, which

  3. Eye-tracking Reveals Abnormal Visual Preference for Geometric Images as an Early Biomarker of an ASD Subtype Associated with Increased Symptom Severity

    Science.gov (United States)

    Pierce, Karen; Marinero, Steven; Hazin, Roxana; McKenna, Benjamin; Barnes, Cynthia Carter; Malige, Ajith

    2015-01-01

    Background Clinically and biologically, ASD is heterogeneous. Unusual patterns of visual preference as indexed by eye-tracking are hallmarks, yet whether they can be used to define an early biomarker of ASD as a whole, or leveraged to define a subtype is unclear. To begin to examine this issue, large cohorts are required. Methods A sample of 334 toddlers from 6 distinct groups (115 ASD, 20 ASD-Features, 57 DD, 53 Other, 64 TD, and 25 Typ SIB) participated. Toddlers watched a movie containing both geometric and social images. Fixation duration and number of saccades within each AOI and validation statistics for this independent sample computed. Next, to maximize power, data from our previous study (N=110) was added totaling 444 subjects. A subset of toddlers repeated the eye-tracking procedure. Results As in the original study, a subset of toddlers with ASD fixated on geometric images greater than 69%. Using this cutoff, sensitivity for ASD was 21%, specificity 98%, and PPV 86%. Toddlers with ASD who strongly preferred geometric images had (a) worse cognitive, language, and social skills relative to toddlers with ASD who strongly preferred social images and (b) fewer saccades when viewing geometric images. Unaffected siblings of ASD probands did not show evidence of heightened preference for geometric images. Test-retest reliability was good. Examination of age effects suggest that this test may not be appropriate with children > 4 years. Conclusions Enhanced visual preference for geometric repetition may be an early developmental biomarker of an ASD subtype with more severe symptoms. PMID:25981170

  4. Semantic guidance of eye movements in real-world scenes.

    Science.gov (United States)

    Hwang, Alex D; Wang, Hsueh-Cheng; Pomplun, Marc

    2011-05-25

    The perception of objects in our visual world is influenced by not only their low-level visual features such as shape and color, but also their high-level features such as meaning and semantic relations among them. While it has been shown that low-level features in real-world scenes guide eye movements during scene inspection and search, the influence of semantic similarity among scene objects on eye movements in such situations has not been investigated. Here we study guidance of eye movements by semantic similarity among objects during real-world scene inspection and search. By selecting scenes from the LabelMe object-annotated image database and applying latent semantic analysis (LSA) to the object labels, we generated semantic saliency maps of real-world scenes based on the semantic similarity of scene objects to the currently fixated object or the search target. An ROC analysis of these maps as predictors of subjects' gaze transitions between objects during scene inspection revealed a preference for transitions to objects that were semantically similar to the currently inspected one. Furthermore, during the course of a scene search, subjects' eye movements were progressively guided toward objects that were semantically similar to the search target. These findings demonstrate substantial semantic guidance of eye movements in real-world scenes and show its importance for understanding real-world attentional control. Copyright © 2011 Elsevier Ltd. All rights reserved.

  5. Attachment quality is related to the synchrony of mother and infant monitoring patterns.

    Science.gov (United States)

    Biro, Szilvia; Alink, Lenneke R A; Huffmeijer, Renske; Bakermans-Kranenburg, Marian J; Van IJzendoorn, Marinus H

    2017-06-01

    We investigated whether attachment quality is related to infant-mother dyadic patterns in monitoring animated social situations. Sixty 12-month-old infants and their mothers participated in an eye-tracking study in which they watched abstractly depicted distress interactions involving the separation of a "baby" and a "parent" character followed by reunion or further separation of the two characters. We measured infants' and their mothers' relative fixation duration to the two characters in the animations. We found that infant attachment disorganization moderated the correspondence between the monitoring patterns of infant-mother dyads during the final part of the animations resulting in reunion or separation. Organized infants and their mothers showed complementary monitoring patterns: the more the mothers focused their attention on the "baby" character, the more the infants focused their attention on the "parent" character, and vice versa. Disorganized infant-mother dyads showed the opposite pattern although the correlation was nonsignificant: mothers and their infants focused on the same character. The attachment-related differences in the nature of the synchrony in the attentional processes of infants and their mothers suggest that by 12 months the dyads' representations of social situations reflect their shared social-emotional experiences.

  6. Eye size and visual acuity influence vestibular anatomy in mammals.

    Science.gov (United States)

    Kemp, Addison D; Christopher Kirk, E

    2014-04-01

    The semicircular canals of the inner ear detect head rotations and trigger compensatory movements that stabilize gaze and help maintain visual fixation. Mammals with large eyes and high visual acuity require precise gaze stabilization mechanisms because they experience diminished visual functionality at low thresholds of uncompensated motion. Because semicircular canal radius of curvature is a primary determinant of canal sensitivity, species with large canal radii are expected to be capable of more precise gaze stabilization than species with small canal radii. Here, we examine the relationship between mean semicircular canal radius of curvature, eye size, and visual acuity in a large sample of mammals. Our results demonstrate that eye size and visual acuity both explain a significant proportion of the variance in mean canal radius of curvature after statistically controlling for the effects of body mass and phylogeny. These findings suggest that variation in mean semicircular canal radius of curvature among mammals is partly the result of selection for improved gaze stabilization in species with large eyes and acute vision. Our results also provide a possible functional explanation for the small semicircular canal radii of fossorial mammals and plesiadapiforms. Copyright © 2014 Wiley Periodicals, Inc.

  7. Pattern of Eye Disorders in Ogbodo: A Rural Community in Rivers ...

    African Journals Online (AJOL)

    Alasia Datonye

    Department of Internal Medicine * and Opthamology **, University of Port Harcourt Teaching. Hospital, Port ... eye care and prevention of blindness. Methods: The eye .... percent and age related macular degeneration (AMRD) in. 3.7 percent of ...

  8. CSF coccidioides complement fixation

    Science.gov (United States)

    ... this page: //medlineplus.gov/ency/article/003526.htm CSF coccidioides complement fixation test To use the sharing features on this page, please enable JavaScript. CSF coccidioides complement fixation is a test that checks ...

  9. Pattern of Uveitis in a Referral Eye Clinic in North India

    Directory of Open Access Journals (Sweden)

    Singh Ramandeep

    2004-01-01

    Full Text Available Purpose: To report the pattern of uveitis in a north Indian tertiary eye center. Methods: A retrospective study was done to identify the pattern of uveitis in a uveitis clinic population of a major referral center in north India from January 1996 to June 2001. A standard clinical protocol, the "naming and meshing" approach with tailored laboratory investigations, was used for the final diagnosis. Results: 1233 patients were included in the study; 641 (51.98% were males and 592 (48.01% females ranging in age from 1.5 to 75 years. The anterior uveitis was seen in 607 patients (49.23% followed by posterior uveitis (247 patients, 20.23%, intermediate uveitis (198 patients, 16.06% and panuveitis (181 patients, 14.68%. A specific diagnosis could be established in 602 patients (48.82%. The infective aetiology was seen in 179 patients, of which tuberculosis was the commonest cause in 125 patients followed by toxoplasmosis (21 patients, 11.7%. Non-infectious aetiology was seen in 423 patients, of which ankylosing spondylitis was the commonest cause in 80 patients followed by sepigionous choroidopathy (62 patients, 14.65% . Conclusion: Tuberculosis and toxoplasmosis were the commonest form of infective uveitis, while ankylosing spondylitis and serpiginous choroidopathy were commonly seen as the non-infective causes of uveitis in North India.

  10. Complement fixation test to C burnetii

    Science.gov (United States)

    ... complement fixation test; Coxiella burnetii - complement fixation test; C burnetii - complement fixation test ... a specific foreign substance ( antigen ), in this case, C burnetii . Antibodies defend the body against bacteria, viruses, ...

  11. Research on Eye Movement Tracking in ESL Reading

    Directory of Open Access Journals (Sweden)

    Wenlian ZHAN

    2014-06-01

    Full Text Available Eye movement behavior in reading can reflect on-line cognitive process. Through the on-line measure of eye movement, under relatively natural reading condition, data of the reader’ s eye movement in the text can be obtained in processing information, and thus help to reveal the internal cognitive mechanisms in reading. With the development of intelligentization, serialization and portable direction in eye tracker, there exist great number of studies on eye movement tracking, but studies on eye movement features in ESL reading are rare. In such circumstances, this paper mainly illustrates eye movement patterns, the relationship between eye movement and perceptual processing, and eye movement control in ESL reading.

  12. Modeling control of eye orientation in three dimensions. I. Role of muscle pulleys in determining saccadic trajectory.

    Science.gov (United States)

    Raphan, T

    1998-05-01

    This study evaluates the effects of muscle axis shifts on the performance of a vector velocity-position integrator in the CNS. Earlier models of the oculomotor plant assumed that the muscle axes remained fixed relative to the head as the eye rotated into secondary and tertiary eye positions. Under this assumption, the vector integrator model generates torsional transients as the eye moves from secondary to tertiary positions of fixation. The torsional transient represents an eye movement response to a spatial mismatch between the torque axes that remain fixed in the head and the displacement plane that changes by half the angle of the change in eye orientation. When muscle axis shifts were incorporated into the model, the torque axes were closer to the displacement plane at each eye orientation throughout the trajectory, and torsional transients were reduced dramatically. Their size and dynamics were close to reported data. It was also shown that when the muscle torque axes were rotated by 50% of the eye rotation, there was no torsional transient and Listing's law was perfectly obeyed. When muscle torque axes rotated >50%, torsional transients reversed direction compared with what occurred for muscle axis shifts of law is implemented by the oculomotor plant subject to a two-dimensional command signal that is confined to the pitch-yaw plane, having zero torsion. Saccades that bring the eye to orientations outside Listing's plane could easily be corrected by a roll pulse that resets the roll state of the velocity-position integrator to zero. This would be a simple implementation of the corrective controller suggested by Van Opstal and colleagues. The model further indicates that muscle axis shifts together with the torque orientation relationship for tissue surrounding the eye and Newton's laws of motion form a sufficient plant model to explain saccadic trajectories and periods of fixation when driven by a vector command confined to the pitch-yaw plane. This implies

  13. Improvement of design of a surgical interface using an eye tracking device.

    Science.gov (United States)

    Erol Barkana, Duygun; Açık, Alper; Duru, Dilek Goksel; Duru, Adil Deniz

    2014-05-07

    Surgical interfaces are used for helping surgeons in interpretation and quantification of the patient information, and for the presentation of an integrated workflow where all available data are combined to enable optimal treatments. Human factors research provides a systematic approach to design user interfaces with safety, accuracy, satisfaction and comfort. One of the human factors research called user-centered design approach is used to develop a surgical interface for kidney tumor cryoablation. An eye tracking device is used to obtain the best configuration of the developed surgical interface. Surgical interface for kidney tumor cryoablation has been developed considering the four phases of user-centered design approach, which are analysis, design, implementation and deployment. Possible configurations of the surgical interface, which comprise various combinations of menu-based command controls, visual display of multi-modal medical images, 2D and 3D models of the surgical environment, graphical or tabulated information, visual alerts, etc., has been developed. Experiments of a simulated cryoablation of a tumor task have been performed with surgeons to evaluate the proposed surgical interface. Fixation durations and number of fixations at informative regions of the surgical interface have been analyzed, and these data are used to modify the surgical interface. Eye movement data has shown that participants concentrated their attention on informative regions more when the number of displayed Computer Tomography (CT) images has been reduced. Additionally, the time required to complete the kidney tumor cryoablation task by the participants had been decreased with the reduced number of CT images. Furthermore, the fixation durations obtained after the revision of the surgical interface are very close to what is observed in visual search and natural scene perception studies suggesting more efficient and comfortable interaction with the surgical interface. The

  14. Sutureless Intrascleral Fixated Intraocular Lens Implantation.

    Science.gov (United States)

    Karadag, Remzi; Celik, Haci Ugur; Bayramlar, Huseyin; Rapuano, Christopher J

    2016-08-01

    To review sutureless intrascleral intraocular lens (IOL) fixation methods. Review of published literature. Sutureless intrascleral IOL fixation methods are newer and have been developed to eliminate the suture-related complications of sutured scleral fixation methods such as suture-induced inflammation or infection and IOL dislocation or subluxation due to suture degradation or suture breakage. Sutureless intrascleral fixation methods aim for intrascleral haptic fixation to achieve stability of the IOL. Various methods of sutureless scleral fixation have been described. Using a needle, a blade, or a trochar, sclerostomies are created in all techniques for intraocular access. Some surgeons prefer to create scleral tunnels, whereas others use scleral flaps for scleral fixation of haptics. The stability of IOLs is attained by the scar tissue formed around the haptics. Short-term results of these new methods are acceptable; studies including more cases with longer follow-up are needed to determine their long-term success. [J Cataract Refract Surg. 2016;32(9):586-597.]. Copyright 2016, SLACK Incorporated.

  15. Listening to music reduces eye movements.

    Science.gov (United States)

    Schäfer, Thomas; Fachner, Jörg

    2015-02-01

    Listening to music can change the way that people visually experience the environment, probably as a result of an inwardly directed shift of attention. We investigated whether this attentional shift can be demonstrated by reduced eye movement activity, and if so, whether that reduction depends on absorption. Participants listened to their preferred music, to unknown neutral music, or to no music while viewing a visual stimulus (a picture or a film clip). Preference and absorption were significantly higher for the preferred music than for the unknown music. Participants exhibited longer fixations, fewer saccades, and more blinks when they listened to music than when they sat in silence. However, no differences emerged between the preferred music condition and the neutral music condition. Thus, music significantly reduces eye movement activity, but an attentional shift from the outer to the inner world (i.e., to the emotions and memories evoked by the music) emerged as only one potential explanation. Other explanations, such as a shift of attention from visual to auditory input, are discussed.

  16. Blink patterns and lid-contact times in dry-eye and normal subjects

    Directory of Open Access Journals (Sweden)

    Ousler GW 3rd

    2014-05-01

    Full Text Available George W Ousler 3rd,1 Mark B Abelson,1,2 Patrick R Johnston,1 John Rodriguez,1 Keith Lane,1 Lisa M Smith11Ora, Andover, MA, USA; 2Department of Ophthalmology, Harvard Medical School, Boston, MA, USAPurpose: To classify blinks in dry eye and normal subjects into six subtypes, and to define the blink rate and duration within each type of blink, as well as the total lid-contact time/minute.Materials and methods: This was a single-centered, prospective, double-blind study of eleven dry-eye and ten normal subjects. Predefined subjects watched a video while blinks were recorded for 10 minutes. Partial blinks were classified by percentage closure of maximal palpebral fissure opening: 25%, 50%, 75%. Complete blinks were characterized as full (>0 seconds, extended (>0.1 seconds, or superextended (>0.5 seconds. The mean duration of each type of blink was determined and standardized per minute as total lid-contact time.Results: Total blinks observed were 4,990 (1,414 normal, 3,756 dry eye: 1,809 (50.59% partial and 1,767 (49.41% complete blinks among dry-eye subjects versus 741 (52.90% partial and 673 (47.60% complete blinks among normal subjects. Only superextended blinks of ≥0.5-second duration were significantly more frequent in dry-eye subjects than normals (2.3% versus 0.2%, respectively; P=0.023. Total contact time was seven times higher in dry-eye subjects than normals (0.565 versus 0.080 seconds, respectively; P<0.001. Isolating only extended blinks (>0.1 second, the average contact time (seconds was four times longer in dry-eye versus normal subjects (2.459 in dry eye, 0.575 in normals; P=0.003. Isolating only superextended blinks (>0.5 seconds, average contact time was also significantly different (7.134 in dry eye, 1.589 in normals; P<0.001. The contact rate for all full closures was 6.4 times longer in dry-eye (0.045 versus 0.007, P<0.001 than normal subjects.Conclusion: Dry-eye subjects spent 4.5% of a

  17. Eye movements during listening reveal spontaneous grammatical processing.

    Science.gov (United States)

    Huette, Stephanie; Winter, Bodo; Matlock, Teenie; Ardell, David H; Spivey, Michael

    2014-01-01

    Recent research using eye-tracking typically relies on constrained visual contexts in particular goal-oriented contexts, viewing a small array of objects on a computer screen and performing some overt decision or identification. Eyetracking paradigms that use pictures as a measure of word or sentence comprehension are sometimes touted as ecologically invalid because pictures and explicit tasks are not always present during language comprehension. This study compared the comprehension of sentences with two different grammatical forms: the past progressive (e.g., was walking), which emphasizes the ongoing nature of actions, and the simple past (e.g., walked), which emphasizes the end-state of an action. The results showed that the distribution and timing of eye movements mirrors the underlying conceptual structure of this linguistic difference in the absence of any visual stimuli or task constraint: Fixations were shorter and saccades were more dispersed across the screen, as if thinking about more dynamic events when listening to the past progressive stories. Thus, eye movement data suggest that visual inputs or an explicit task are unnecessary to solicit analog representations of features such as movement, that could be a key perceptual component to grammatical comprehension.

  18. Eye movements during listening reveal spontaneous grammatical processing

    Directory of Open Access Journals (Sweden)

    Stephanie eHuette

    2014-05-01

    Full Text Available Recent research using eye-tracking typically relies on constrained visual contexts in particular goal-oriented contexts, viewing a small array of objects on a computer screen and performing some overt decision or identification. Eyetracking paradigms that use pictures as a measure of word or sentence comprehension are sometimes touted as ecologically invalid because pictures and explicit tasks are not always present during language comprehension. This study compared the comprehension of sentences with two different grammatical forms: the past progressive (e.g., was walking, which emphasizes the ongoing nature of actions, and the simple past (e.g., walked, which emphasizes the end-state of an action. The results showed that the distribution and timing of eye movements mirrors the underlying conceptual structure of this linguistic difference in the absence of any visual stimuli or task constraint: Fixations were shorter and saccades were more dispersed across the screen, as if thinking about more dynamic events when listening to the past progressive stories. Thus, eye movement data suggest that visual inputs or an explicit task are unnecessary to solicit analogue representations of features such as movement, that could be a key perceptual component to grammatical comprehension.

  19. [Treatment of pediatric distal femur fractures by external fixator combined with limited internal fixation].

    Science.gov (United States)

    Wei, Sheng-wang; Shi, Zhan-ying; Hu, Ju-zheng; Wu, Hao

    2016-03-01

    To discuss the clinical effects of external fixator combined with limited internal fixation in the treatment of pediatric distal femur fractures. From January 2008 to June 2014, 17 children of distal femur fractures were treated by external fixator combined with limited internal fixation. There were 12 males and 5 females, aged from 6 to 13 years old with an average of 10.2 years, ranged in the course of disease from 1 h to 2 d. Preoperative diagnoses were confirmed by X-ray films in all children. There were 11 patients with supracondylar fracture , and 6 patients with intercondylar comminuted fracture. According to AO/ASIF classification, 9 fractures were type A1, 5 cases were type A2,and 3 cases were type C1. The intraoperative and postoperative complications, postoperative radiological examination, lower limbs length and motion of knee joints were observed. Knee joint function was assessed by KSS score. All the patients were followed up from 6 to 38 months with an average of 24.4 months. No nerve or blood vessel injury was found. One case complicated with the external fixation loosening, 2 cases with the infection of pin hole and 3 cases with the leg length discrepancy. Knee joint mobility and length measurement (compared with the contralateral), the average limited inflexion was 10 degrees (0 degrees to 20 degrees), the average limited straight was 4 degrees (0 degrees to 10), the average varus or valgus angle was 3 degrees (0 degrees to 5 degrees). KSS of the injured side was (96.4 +/- 5.0) points at final follow-up, 16 cases got excellent results and 1 good. All fractures obtained healing and no epiphyseal closed early was found. External fixator combined with limited internal fixation has advantages of simple operation, reliable fixation, early functional exercise in treating pediatric distal femurs fractures.

  20. Comparison of screw fixation with elastic fixation methods in the treatment of syndesmosis injuries in ankle fractures.

    Science.gov (United States)

    Seyhan, Mustafa; Donmez, Ferdi; Mahirogullari, Mahir; Cakmak, Selami; Mutlu, Serhat; Guler, Olcay

    2015-07-01

    17 patients with ankle syndesmosic injury were treated with a 4.5mm single cortical screw fixation (passage of screw 4 cortices) and 15 patients were treated with single-level elastic fixation material. All patients were evaluated according to the AOFAS ankle and posterior foot scale at the third, sixth and twelfth months after the fixation. The ankle range of movement was recorded together with the healthy side. The Student's t test was used for statistical comparisons. No statistical significant difference was observed between the AOFAS scores (p>0.05). The range of dorsiflexion and plantar flexion motion of the elastic fixation group at the 6th and 12th months were significantly better compared to the screw fixation group (pankle syndesmosis injuries. The unnecessary need of a second surgical intervention for removal of the fixation material is another advantageous aspect of this method of fixation. Copyright © 2015. Published by Elsevier Ltd.

  1. Discussion on the planting patterns of alfalfa and meadow fescue in mixed culture and evaluation for their contribution from N2 fixation

    International Nuclear Information System (INIS)

    Yao Yunyin; Zhang Xizhong; Chen Ming

    1996-01-01

    Effects of planting patterns on dry weight, N yield and dinitrogen fixation in alfalfa-meadow fescue pasture are studied by using split plot design in the field for two successive years. The results show that the pattern of row seeding in mixture (RM) is superior to the pattern of broadcasting in mixture (BM) and intercropping (TC), and advantageous to develop the superiority of legume-grass mixed pasture. The annual average of dry weight for RM, BM and TC is 1535.9 g/m 2 , 1208.8 g/m 2 and 1249.3 g/m 2 respectively. The annual average of N yield of them is 50.83 g(N)/m 2 , 36.65 g(N)/m 2 and 36.86 g(N)/m 2 . The annual average Ndfa is 42.37 g(N)/m 2 , 28.21 g(N)/m 2 and 28.42 g(N)/m 2 , and %Ndfa is 83.4%, 77.0% and 77.1% for RM, BM and TC respectively. The comparison of 15 N isotope dilution method, natural 15 N abundance method and total N difference method to measure %Ndfa of herbage for all the treatments are made

  2. High-speed adaptive optics line scan confocal retinal imaging for human eye.

    Science.gov (United States)

    Lu, Jing; Gu, Boyu; Wang, Xiaolin; Zhang, Yuhua

    2017-01-01

    Continuous and rapid eye movement causes significant intraframe distortion in adaptive optics high resolution retinal imaging. To minimize this artifact, we developed a high speed adaptive optics line scan confocal retinal imaging system. A high speed line camera was employed to acquire retinal image and custom adaptive optics was developed to compensate the wave aberration of the human eye's optics. The spatial resolution and signal to noise ratio were assessed in model eye and in living human eye. The improvement of imaging fidelity was estimated by reduction of intra-frame distortion of retinal images acquired in the living human eyes with frame rates at 30 frames/second (FPS), 100 FPS, and 200 FPS. The device produced retinal image with cellular level resolution at 200 FPS with a digitization of 512×512 pixels/frame in the living human eye. Cone photoreceptors in the central fovea and rod photoreceptors near the fovea were resolved in three human subjects in normal chorioretinal health. Compared with retinal images acquired at 30 FPS, the intra-frame distortion in images taken at 200 FPS was reduced by 50.9% to 79.7%. We demonstrated the feasibility of acquiring high resolution retinal images in the living human eye at a speed that minimizes retinal motion artifact. This device may facilitate research involving subjects with nystagmus or unsteady fixation due to central vision loss.

  3. External fixation combined with delayed internal fixation in treatment of tibial plateau fractures with dislocation.

    Science.gov (United States)

    Tao, Xingguang; Chen, Nong; Pan, Fugen; Cheng, Biao

    2017-10-01

    The aim of this study was to evaluate the clinical efficacy of external fixation, delayed open reduction, and internal fixation in treating tibial plateau fracture with dislocation.Clinical data of 34 patients diagnosed with tibial plateau fracture complicated with dislocation between January 2009 and May 2015 were retrospectively analyzed. Fifteen patients in group A underwent early calcaneus traction combined with open reduction and internal fixation and 19 in group B received early external fixation combined with delayed open reduction and internal fixation. Operation time, postoperative complication, bone healing time, knee joint range of motion, initial weight-bearing time, Rasmussen tibial plateau score, and knee function score (HSS) were statistically compared between 2 groups.The mean follow-up time was 18.6 months (range: 5-24 months). The mean operation time in group A was 96 minutes, significantly longer than 71 minutes in group B (P  .05). In group A, initial weight-bearing time in group A was (14.0 ± 3.6) weeks, significantly differing from (12.9 ± 2.8) weeks in group B (P  0.05). Rasmussen tibial plateau score in group A was slightly lower than that in group B (P > .05). The excellent rate of knee joint function in group A was 80% and 84.21% in group B (P > .05).External fixation combined with delayed open reduction and internal fixation is a safer and more efficacious therapy of tibial plateau fracture complicated with dislocation compared with early calcaneus traction and open reduction and internal fixation.

  4. Eye movements discriminate fatigue due to chronotypical factors and time spent on task--a double dissociation.

    Directory of Open Access Journals (Sweden)

    Dario Cazzoli

    Full Text Available Systematic differences in circadian rhythmicity are thought to be a substantial factor determining inter-individual differences in fatigue and cognitive performance. The synchronicity effect (when time of testing coincides with the respective circadian peak period seems to play an important role. Eye movements have been shown to be a reliable indicator of fatigue due to sleep deprivation or time spent on cognitive tasks. However, eye movements have not been used so far to investigate the circadian synchronicity effect and the resulting differences in fatigue. The aim of the present study was to assess how different oculomotor parameters in a free visual exploration task are influenced by: a fatigue due to chronotypical factors (being a 'morning type' or an 'evening type'; b fatigue due to the time spent on task. Eighteen healthy participants performed a free visual exploration task of naturalistic pictures while their eye movements were recorded. The task was performed twice, once at their optimal and once at their non-optimal time of the day. Moreover, participants rated their subjective fatigue. The non-optimal time of the day triggered a significant and stable increase in the mean visual fixation duration during the free visual exploration task for both chronotypes. The increase in the mean visual fixation duration correlated with the difference in subjectively perceived fatigue at optimal and non-optimal times of the day. Conversely, the mean saccadic speed significantly and progressively decreased throughout the duration of the task, but was not influenced by the optimal or non-optimal time of the day for both chronotypes. The results suggest that different oculomotor parameters are discriminative for fatigue due to different sources. A decrease in saccadic speed seems to reflect fatigue due to time spent on task, whereas an increase in mean fixation duration a lack of synchronicity between chronotype and time of the day.

  5. Quiet Eye Duration Is Responsive to Variability of Practice and to the Axis of Target Changes

    Science.gov (United States)

    Horn, Robert R.; Okumura, Michelle S.; Alexander, Melissa G. F.; Gardin, Fredrick A.; Sylvester, Curtis T.

    2012-01-01

    We tested the hypothesis that quiet eye, the final fixation before the initiation of a movement in aiming tasks, is used to scale the movement's parameters. Two groups of 12 participants (N = 24) threw darts to targets in the horizontal and vertical axes under conditions of higher (random) or lower (blocked) target variability. Supporting our…

  6. Nitrogen Fixation Aligns with nifH Abundance and Expression in Two Coral Trophic Functional Groups

    KAUST Repository

    Pogoreutz, Claudia; Radecker, Nils; Cardenas, Anny; Gä rdes, Astrid; Wild, Christian; Voolstra, Christian R.

    2017-01-01

    Microbial nitrogen fixation (diazotrophy) is a functional trait widely associated with tropical reef-building (scleractinian) corals. While the integral role of nitrogen fixation in coral nutrient dynamics is recognized, its ecological significance across different coral functional groups remains yet to be evaluated. Here we set out to compare molecular and physiological patterns of diazotrophy (i.e., nifH gene abundance and expression as well as nitrogen fixation rates) in two coral families with contrasting trophic strategies: highly heterotrophic, free-living members of the family Fungiidae (Pleuractis granulosa, Ctenactis echinata), and mostly autotrophic coral holobionts with low heterotrophic capacity (Pocilloporidae: Pocillopora verrucosa, Stylophora pistillata). The Fungiidae exhibited low diazotroph abundance (based on nifH gene copy numbers) and activity (based on nifH gene expression and the absence of detectable nitrogen fixation rates). In contrast, the mostly autotrophic Pocilloporidae exhibited nifH gene copy numbers and gene expression two orders of magnitude higher than in the Fungiidae, which coincided with detectable nitrogen fixation activity. Based on these data, we suggest that nitrogen fixation compensates for the low heterotrophic nitrogen uptake in autotrophic corals. Consequently, the ecological importance of diazotrophy in coral holobionts may be determined by the trophic functional group of the host.

  7. Nitrogen Fixation Aligns with nifH Abundance and Expression in Two Coral Trophic Functional Groups

    KAUST Repository

    Pogoreutz, Claudia

    2017-06-28

    Microbial nitrogen fixation (diazotrophy) is a functional trait widely associated with tropical reef-building (scleractinian) corals. While the integral role of nitrogen fixation in coral nutrient dynamics is recognized, its ecological significance across different coral functional groups remains yet to be evaluated. Here we set out to compare molecular and physiological patterns of diazotrophy (i.e., nifH gene abundance and expression as well as nitrogen fixation rates) in two coral families with contrasting trophic strategies: highly heterotrophic, free-living members of the family Fungiidae (Pleuractis granulosa, Ctenactis echinata), and mostly autotrophic coral holobionts with low heterotrophic capacity (Pocilloporidae: Pocillopora verrucosa, Stylophora pistillata). The Fungiidae exhibited low diazotroph abundance (based on nifH gene copy numbers) and activity (based on nifH gene expression and the absence of detectable nitrogen fixation rates). In contrast, the mostly autotrophic Pocilloporidae exhibited nifH gene copy numbers and gene expression two orders of magnitude higher than in the Fungiidae, which coincided with detectable nitrogen fixation activity. Based on these data, we suggest that nitrogen fixation compensates for the low heterotrophic nitrogen uptake in autotrophic corals. Consequently, the ecological importance of diazotrophy in coral holobionts may be determined by the trophic functional group of the host.

  8. Individual differences in language ability are related to variation in word recognition, not speech perception: Evidence from eye-movements

    Science.gov (United States)

    McMurray, Bob; Munson, Cheyenne; Tomblin, J. Bruce

    2013-01-01

    Purpose This study examined speech perception deficits associated with individual differences in language ability contrasting auditory, phonological or lexical accounts by asking if lexical competition is differentially sensitive to fine-grained acoustic variation. Methods 74 adolescents with a range of language abilities (including 35 impaired) participated in an experiment based on McMurray, Tanenhaus and Aslin (2002). Participants heard tokens from six 9-step Voice Onset Time (VOT) continua spanning two words (beach/peach, beak/peak, etc), while viewing a screen containing pictures of those words and two unrelated objects. Participants selected the referent while eye-movements to each picture were monitored as a measure of lexical activation. Fixations were examined as a function of both VOT and language ability. Results Eye-movements were sensitive to within-category VOT differences: as VOT approached the boundary, listeners made more fixations to the competing word. This did not interact with language ability, suggesting that language impairment is not associated with differential auditory sensitivity or phonetic categorization. Listeners with poorer language skills showed heightened competitors fixations overall, suggesting a deficit in lexical processes. Conclusions Language impairment may be better characterized by a deficit in lexical competition (inability to suppress competing words), rather than differences phonological categorization or auditory abilities. PMID:24687026

  9. Individual differences in language ability are related to variation in word recognition, not speech perception: evidence from eye movements.

    Science.gov (United States)

    McMurray, Bob; Munson, Cheyenne; Tomblin, J Bruce

    2014-08-01

    The authors examined speech perception deficits associated with individual differences in language ability, contrasting auditory, phonological, or lexical accounts by asking whether lexical competition is differentially sensitive to fine-grained acoustic variation. Adolescents with a range of language abilities (N = 74, including 35 impaired) participated in an experiment based on McMurray, Tanenhaus, and Aslin (2002). Participants heard tokens from six 9-step voice onset time (VOT) continua spanning 2 words (beach/peach, beak/peak, etc.) while viewing a screen containing pictures of those words and 2 unrelated objects. Participants selected the referent while eye movements to each picture were monitored as a measure of lexical activation. Fixations were examined as a function of both VOT and language ability. Eye movements were sensitive to within-category VOT differences: As VOT approached the boundary, listeners made more fixations to the competing word. This did not interact with language ability, suggesting that language impairment is not associated with differential auditory sensitivity or phonetic categorization. Listeners with poorer language skills showed heightened competitors fixations overall, suggesting a deficit in lexical processes. Language impairment may be better characterized by a deficit in lexical competition (inability to suppress competing words), rather than differences in phonological categorization or auditory abilities.

  10. Quiet eye training improves surgical knot tying more than traditional technical training: a randomized controlled study.

    Science.gov (United States)

    Causer, Joe; Harvey, Adrian; Snelgrove, Ryan; Arsenault, Gina; Vickers, Joan N

    2014-08-01

    We examined the effectiveness of technical training (TT) and quiet eye training (QE) on the performance of one-handed square knot tying in surgical residents. Twenty surgical residents were randomly assigned to the 2 groups and completed pretest, training, retention, and transfer tests. Participants wore a mobile eye tracker that simultaneously recorded their gaze and hand movements. Dependent variables were knot tying performance (%), QE duration (%), number of fixations, total movement time (s), and hand movement phase time (s). The QE training group had significantly higher performance scores, a longer QE duration, fewer fixations, faster total knot tying times, and faster movement phase times compared with the TT group. The QE group maintained performance in the transfer test, whereas the TT group significantly decreased performance from retention to transfer. QE training significantly improved learning, retention, and transfer of surgical knot tying compared with a traditional technical approach. Both performance effectiveness (performance outcome) and movement efficiency (hand movement times) were improved using QE modeling, instruction, and feedback. Copyright © 2014 Elsevier Inc. All rights reserved.

  11. Management and follow up of tibial plateau fractures by ′T′ clamp external fixator and limited internal fixation

    Directory of Open Access Journals (Sweden)

    Thimmegowda M

    2005-01-01

    Full Text Available Background: Tibial plateau fractures are difficult to treat especially when soft tissue is compromised by open reduction and internal fixation. Many methods have be1en tried in the past to manage these cases of which external fixation were shown to be effective as they limit the soft tissue and wound complications. Methods: Complex tibial plateau fractures of sixteen patients were treated by closed reduction, fixation of articular fragments by screws and application of unilateral external fixator. The external fixator was kept in place till fracture united clinically and radiologically. The patients were followed up for at least one year to assess the function of the knee joint Results: The average duration of external fixation was 13 weeks. All the fractures healed. Pin track infection (five patients and instability (six patients of the knee were encountered with this procedure. The average duration of follow up was 62 weeks. The mean range of motion was 1250 arc. The IOWA knee score averaged 90.3 points. Conclusions: External fixation with limited internal fixation may be effective in the management of complex tibial plateau fractures which requires further support from studies with large sample size. ′T′ clamp external fixation with limited Internal fixation is the procedure of choice when alignment, stability, early mobilisation is required in a soft tissue compromised tibial plateau fractures.

  12. Characterization of Visual Scanning Patterns in Air Traffic Control.

    Science.gov (United States)

    McClung, Sarah N; Kang, Ziho

    2016-01-01

    Characterization of air traffic controllers' (ATCs') visual scanning strategies is a challenging issue due to the dynamic movement of multiple aircraft and increasing complexity of scanpaths (order of eye fixations and saccades) over time. Additionally, terminologies and methods are lacking to accurately characterize the eye tracking data into simplified visual scanning strategies linguistically expressed by ATCs. As an intermediate step to automate the characterization classification process, we (1) defined and developed new concepts to systematically filter complex visual scanpaths into simpler and more manageable forms and (2) developed procedures to map visual scanpaths with linguistic inputs to reduce the human judgement bias during interrater agreement. The developed concepts and procedures were applied to investigating the visual scanpaths of expert ATCs using scenarios with different aircraft congestion levels. Furthermore, oculomotor trends were analyzed to identify the influence of aircraft congestion on scan time and number of comparisons among aircraft. The findings show that (1) the scanpaths filtered at the highest intensity led to more consistent mapping with the ATCs' linguistic inputs, (2) the pattern classification occurrences differed between scenarios, and (3) increasing aircraft congestion caused increased scan times and aircraft pairwise comparisons. The results provide a foundation for better characterizing complex scanpaths in a dynamic task and automating the analysis process.

  13. Web pages: What can you see in a single fixation?

    Science.gov (United States)

    Jahanian, Ali; Keshvari, Shaiyan; Rosenholtz, Ruth

    2018-01-01

    Research in human vision suggests that in a single fixation, humans can extract a significant amount of information from a natural scene, e.g. the semantic category, spatial layout, and object identities. This ability is useful, for example, for quickly determining location, navigating around obstacles, detecting threats, and guiding eye movements to gather more information. In this paper, we ask a new question: What can we see at a glance at a web page - an artificial yet complex "real world" stimulus? Is it possible to notice the type of website, or where the relevant elements are, with only a glimpse? We find that observers, fixating at the center of a web page shown for only 120 milliseconds, are well above chance at classifying the page into one of ten categories. Furthermore, this ability is supported in part by text that they can read at a glance. Users can also understand the spatial layout well enough to reliably localize the menu bar and to detect ads, even though the latter are often camouflaged among other graphical elements. We discuss the parallels between web page gist and scene gist, and the implications of our findings for both vision science and human-computer interaction.

  14. Magnetoactive elastomer as an element of a magnetic retina fixator

    Science.gov (United States)

    Makarova, L. A.; Nadzharyan, T. A.; Alekhina, Yu A.; Stepanov, G. V.; Kazimirova, E. G.; Perov, N. S.; Kramarenko, E. Yu

    2017-09-01

    We explore the possibility of creating an effective retinal fixator on the basis of magnetoactive elastomers (MAEs) and systems of permanent magnets. MAEs consist of silicone elastomer matrix with embedded magnetic iron microparticles. We study theoretically and experimentally magnetic forces acting between MAE samples and permanent magnets in various configurations. The theoretical model is based around classical magnetostatics and Maxwell equations with different parameters accounting for peculiarities of the material and the setup. Approximation of the experimentally measured magnetization curves for MAE samples was used to find input parameters for the theoretical model. To test the model, we conducted a series of experimental measurements of magnetic forces accompanied by model predictions for the system of one cylindrical magnet and a cuboid MAE sample. Calculated dependences of the average pressure arising from magnetic interactions on the distance between the closest faces of MAE samples and a permanent magnet are in a good agreement with the experimental data. The proof on concept for smaller magnetic systems required for eye surgery includes data for 10 magnets configuration and a thin MAE band. This research demonstrates high prospects of using MAE as an element of a magnetic fixator for treatment of complicated retinal detachments.

  15. A Meta-Analysis for Postoperative Complications in Tibial Plafond Fracture: Open Reduction and Internal Fixation Versus Limited Internal Fixation Combined With External Fixator.

    Science.gov (United States)

    Wang, Dong; Xiang, Jian-Ping; Chen, Xiao-Hu; Zhu, Qing-Tang

    2015-01-01

    The treatment of tibial plafond fractures is challenging to foot and ankle surgeons. Open reduction and internal fixation and limited internal fixation combined with an external fixator are 2 of the most commonly used methods of tibial plafond fracture repair. However, conclusions regarding the superior choice remain controversial. The present meta-analysis aimed to quantitatively compare the postoperative complications between open reduction and internal fixation and limited internal fixation combined with an external fixator for tibial plafond fractures. Nine studies with 498 fractures in 494 patients were included in the present study. The meta-analysis found no significant differences in bone healing complications (risk ratio [RR] 1.17, 95% confidence interval [CI] 0.68 to 2.01, p = .58], nonunion (RR 1.09, 95% CI 0.51 to 2.36, p = .82), malunion or delayed union (RR 1.24, 95% CI 0.57 to 2.69, p = .59), superficial (RR 1.56, 95% CI 0.43 to 5.61, p = .50) and deep (RR 1.89, 95% CI 0.62 to 5.80) infections, arthritis symptoms (RR 1.20, 95% CI 0.92 to 1.58, p = .18), or chronic osteomyelitis (RR 0.31, 95% CI 0.05 to 1.84, p = .20) between the 2 groups. Copyright © 2015 American College of Foot and Ankle Surgeons. Published by Elsevier Inc. All rights reserved.

  16. Enhanced-Depth Imaging Optical Coherence Tomography of the Human Choroid In Vivo Compared With Histology After Enucleation

    DEFF Research Database (Denmark)

    Li, Xiao Qiang; Heegaard, Steffen; Kiilgaard, Jens Folke

    2016-01-01

    PURPOSE: This study compared in vivo enhanced-depth imaging optical coherence tomography (EDI-OCT) with ex vivo histology of the choroid in human eyes. METHODS: Three eyes in three patients with advanced iris melanoma without posterior segment involvement underwent EDI-OCT less than 24 hours prior...... to enucleation and, in one eye, immediately after enucleation. Following fixation in 4% buffered formaldehyde and paraffin embedding, serial sections of the whole eye were cut horizontally, mounted, stained with hematoxylin-eosin and digitized. Alignment between histology and EDI-OCT was made on landmarks...... and subfoveal choroid thickness reduced to 56%, 45%, and 56%, respectively, of its in vivo thickness on EDI-OCT. CONCLUSIONS: There were no identifiable discrepancies in choroidal structural patterns between clinical EDI-OCT and histologic sections except that after enucleation and histologic fixation choroidal...

  17. Prevalence of Eye Disease among Inmates of Ilesa Prison ...

    African Journals Online (AJOL)

    Introduction: In Nigeria, like many other developing countries where prisoners have restricted access to health care including eye health care, severe untreated eye disorders are common causes of ocular morbidity and blindness. This study was carried out to determine the prevalence and pattern of eye disease among ...

  18. Simultaneous recordings of human microsaccades and drifts with a contemporary video eye tracker and the search coil technique.

    Directory of Open Access Journals (Sweden)

    Michael B McCamy

    Full Text Available Human eyes move continuously, even during visual fixation. These "fixational eye movements" (FEMs include microsaccades, intersaccadic drift and oculomotor tremor. Research in human FEMs has grown considerably in the last decade, facilitated by the manufacture of noninvasive, high-resolution/speed video-oculography eye trackers. Due to the small magnitude of FEMs, obtaining reliable data can be challenging, however, and depends critically on the sensitivity and precision of the eye tracking system. Yet, no study has conducted an in-depth comparison of human FEM recordings obtained with the search coil (considered the gold standard for measuring microsaccades and drift and with contemporary, state-of-the art video trackers. Here we measured human microsaccades and drift simultaneously with the search coil and a popular state-of-the-art video tracker. We found that 95% of microsaccades detected with the search coil were also detected with the video tracker, and 95% of microsaccades detected with video tracking were also detected with the search coil, indicating substantial agreement between the two systems. Peak/mean velocities and main sequence slopes of microsaccades detected with video tracking were significantly higher than those of the same microsaccades detected with the search coil, however. Ocular drift was significantly correlated between the two systems, but drift speeds were higher with video tracking than with the search coil. Overall, our combined results suggest that contemporary video tracking now approaches the search coil for measuring FEMs.

  19. Surveillance Tools Emerging From Search Engines and Social Media Data for Determining Eye Disease Patterns.

    Science.gov (United States)

    Deiner, Michael S; Lietman, Thomas M; McLeod, Stephen D; Chodosh, James; Porco, Travis C

    2016-09-01

    Internet-based search engine and social media data may provide a novel complementary source for better understanding the epidemiologic factors of infectious eye diseases, which could better inform eye health care and disease prevention. To assess whether data from internet-based social media and search engines are associated with objective clinic-based diagnoses of conjunctivitis. Data from encounters of 4143 patients diagnosed with conjunctivitis from June 3, 2012, to April 26, 2014, at the University of California San Francisco (UCSF) Medical Center, were analyzed using Spearman rank correlation of each weekly observation to compare demographics and seasonality of nonallergic conjunctivitis with allergic conjunctivitis. Data for patient encounters with diagnoses for glaucoma and influenza were also obtained for the same period and compared with conjunctivitis. Temporal patterns of Twitter and Google web search data, geolocated to the United States and associated with these clinical diagnoses, were compared with the clinical encounters. The a priori hypothesis was that weekly internet-based searches and social media posts about conjunctivitis may reflect the true weekly clinical occurrence of conjunctivitis. Weekly total clinical diagnoses at UCSF of nonallergic conjunctivitis, allergic conjunctivitis, glaucoma, and influenza were compared using Spearman rank correlation with equivalent weekly data on Tweets related to disease or disease-related keyword searches obtained from Google Trends. Seasonality of clinical diagnoses of nonallergic conjunctivitis among the 4143 patients (2364 females [57.1%] and 1776 males [42.9%]) with 5816 conjunctivitis encounters at UCSF correlated strongly with results of Google searches in the United States for the term pink eye (ρ, 0.68 [95% CI, 0.52 to 0.78]; P < .001) and correlated moderately with Twitter results about pink eye (ρ, 0.38 [95% CI, 0.16 to 0.56]; P < .001) and with clinical diagnosis of influenza (ρ, 0

  20. Attentional bias to betel quid cues: An eye tracking study.

    Science.gov (United States)

    Shen, Bin; Chiu, Meng-Chun; Li, Shuo-Heng; Huang, Guo-Joe; Liu, Ling-Jun; Ho, Ming-Chou

    2016-09-01

    The World Health Organization regards betel quid as a human carcinogen, and DSM-IV and ICD-10 dependence symptoms may develop with heavy use. This study, conducted in central Taiwan, investigated whether betel quid chewers can exhibit overt orienting to selectively respond to the betel quid cues. Twenty-four male chewers' and 23 male nonchewers' eye movements to betel-quid-related pictures and matched pictures were assessed during a visual probe task. The eye movement index showed that betel quid chewers were more likely to initially direct their gaze to the betel quid cues, t(23) = 3.70, p betel quid chewers' attentional bias. The results demonstrated that the betel quid chewers (but not the nonchewers) were more likely to initially direct their gaze to the betel quid cues, and spent more time and were more fixated on them. These findings suggested that when attention is directly measured through the eye tracking technique, this methodology may be more sensitive to detecting attentional biases in betel quid chewers. (PsycINFO Database Record (c) 2016 APA, all rights reserved).

  1. Overcoming fixation with repeated memory suppression.

    Science.gov (United States)

    Angello, Genna; Storm, Benjamin C; Smith, Steven M

    2015-01-01

    Fixation (blocks to memories or ideas) can be alleviated not only by encouraging productive work towards a solution, but, as the present experiments show, by reducing counterproductive work. Two experiments examined relief from fixation in a word-fragment completion task. Blockers, orthographically similar negative primes (e.g., ANALOGY), blocked solutions to word fragments (e.g., A_L_ _GY) in both experiments. After priming, but before the fragment completion test, participants repeatedly suppressed half of the blockers using the Think/No-Think paradigm, which results in memory inhibition. Inhibiting blockers did not alleviate fixation in Experiment 1 when conscious recollection of negative primes was not encouraged on the fragment completion test. In Experiment 2, however, when participants were encouraged to remember negative primes at fragment completion, relief from fixation was observed. Repeated suppression may nullify fixation effects, and promote creative thinking, particularly when fixation is caused by conscious recollection of counterproductive information.

  2. Eighth international congress on nitrogen fixation. Final program

    Energy Technology Data Exchange (ETDEWEB)

    1990-12-31

    This volume contains the proceedings of the Eighth International Congress on Nitrogen Fixation held May 20--26, 1990 in Knoxville, Tennessee. The volume contains abstracts of individual presentations. Sessions were entitled Recent Advances in the Chemistry of Nitrogen Fixation, Plant-microbe Interactions, Limiting Factors of Nitrogen Fixation, Nitrogen Fixation and the Environment, Bacterial Systems, Nitrogen Fixation in Agriculture and Industry, Plant Function, and Nitrogen Fixation and Evolution.

  3. Using eye tracking technology to compare the effectiveness of malignant hyperthermia cognitive aid design.

    Science.gov (United States)

    King, Roderick; Hanhan, Jaber; Harrison, T Kyle; Kou, Alex; Howard, Steven K; Borg, Lindsay K; Shum, Cynthia; Udani, Ankeet D; Mariano, Edward R

    2018-05-15

    Malignant hyperthermia is a rare but potentially fatal complication of anesthesia, and several different cognitive aids designed to facilitate a timely and accurate response to this crisis currently exist. Eye tracking technology can measure voluntary and involuntary eye movements, gaze fixation within an area of interest, and speed of visual response and has been used to a limited extent in anesthesiology. With eye tracking technology, we compared the accessibility of five malignant hyperthermia cognitive aids by collecting gaze data from twelve volunteer participants. Recordings were reviewed and annotated to measure the time required for participants to locate objects on the cognitive aid to provide an answer; cumulative time to answer was the primary outcome. For the primary outcome, there were differences detected between cumulative time to answer survival curves (P typescript with minimal use of single color blocking.

  4. Movimentos oculares e padrões de busca visual em tarefas de rotação mental Eye movements and scan patterns in mental rotation tasks

    Directory of Open Access Journals (Sweden)

    Priscila Covre

    2005-06-01

    Full Text Available O objetivo deste estudo é identificar as estratégias utilizadas nas tarefas de rotação mental pela análise dos traçados dos movimentos oculares. Foi analisado o desempenho de 40 participantes na comparação de pares de objetos tridimensionais rotacionados no eixo y, com diferenças de angulação de 0o a 180o. Foi utilizado um sistema computacional de rastreamento dos movimentos oculares (eyetracking durante a visualização de figuras. Os resultados mostram que tempo de julgamento, duração média das fixações do olho, número de fixações nos objetos e número de alternâncias entre os dois objetos aumentam em função da diferença de angulação. Análise dos traçados oculares, com base na inspeção visual, indica o uso de dois tipos de estratégias: rotação mental em torno dos eixos padrões e comparação independente da orientação. O uso dessas estratégias é discutido com relação ao desempenho dos participantes e à memória de trabalho.The purpose of this paper is to identify the strategies used on mental rotation tasks by analyzing ocular movements. The performance of 40 participants on comparison of pairs of three-dimensional objects, rotated on the y-axis, from 0o to 180o was analyzed. An eye-tracking computerized system was used to track eye movements during scene visualization. Results showed that judgment time, fixation duration, number of fixations and number of switches between the objects increased with rotation angle. Analysis by visual inspection indicates the use of two kinds of strategies: Mental rotation around the standard axis and comparison of orientation-free descriptions. The use of the strategies is discussed with regard to performance and working memory.

  5. Relationship between optical coherence tomography, pattern electroretinogram and automated perimetry in eyes with temporal hemianopia from chiasmal compression.

    Science.gov (United States)

    Monteiro, Mário L R; Cunha, Leonardo P; Costa-Cunha, Luciana V F; Maia, Otacílio O; Oyamada, Maria K

    2009-08-01

    To evaluate the relationship between pattern electroretinogram (PERG) amplitude, macular and retinal nerve fiber layer (RNFL) thickness by optical coherence tomography (OCT), and visual field (VF) loss on standard automated perimetry (SAP) in eyes with temporal hemianopia from chiasmal compression. Forty-one eyes from 41 patients with permanent temporal VF defects from chiasmal compression and 41 healthy subjects underwent transient full-field and hemifield (temporal or nasal) stimulation PERG, SAP and time domain-OCT macular and RNFL thickness measurements. Comparisons were made using Student's t-test. Deviation from normal VF sensitivity for the central 18 degrees of VF was expressed in 1/Lambert units. Correlations between measurements were verified by linear regression analysis. PERG and OCT measurements were significantly lower in eyes with temporal hemianopia than in normal eyes. A significant correlation was found between VF sensitivity loss and full-field or nasal, but not temporal, hemifield PERG amplitude. Likewise a significant correlation was found between VF sensitivity loss and most OCT parameters. No significant correlation was observed between OCT and PERG parameters, except for nasal hemifield amplitude. A significant correlation was observed between several macular and RNFL thickness parameters. In patients with chiasmal compression, PERG amplitude and OCT thickness measurements were significant related to VF loss, but not to each other. OCT and PERG quantify neuronal loss differently, but both technologies are useful in understanding structure-function relationship in patients with chiasmal compression. (ClinicalTrials.gov number, NCT00553761).

  6. Biomechanical stability of a supra-acetabular pedicle screw internal fixation device (INFIX) vs external fixation and plates for vertically unstable pelvic fractures.

    Science.gov (United States)

    Vigdorchik, Jonathan M; Esquivel, Amanda O; Jin, Xin; Yang, King H; Onwudiwe, Ndidi A; Vaidya, Rahul

    2012-09-27

    We have recently developed a subcutaneous anterior pelvic fixation technique (INFIX). This internal fixator permits patients to sit, roll over in bed and lie on their sides without the cumbersome external appliances or their complications. The purpose of this study was to evaluate the biomechanical stability of this novel supraacetabular pedicle screw internal fixation construct (INFIX) and compare it to standard internal fixation and external fixation techniques in a single stance pelvic fracture model. Nine synthetic pelves with a simulated anterior posterior compression type III injury were placed into three groups (External Fixator, INFIX and Internal Fixation). Displacement, total axial stiffness, and the stiffness at the pubic symphysis and SI joint were calculated. Displacement and stiffness were compared by ANOVA with a Bonferroni adjustment for multiple comparisons The mean displacement at the pubic symphysis was 20, 9 and 0.8 mm for external fixation, INFIX and internal fixation, respectively. Plate fixation was significantly stiffer than the INFIX and external Fixator (P = 0.01) at the symphysis pubis. The INFIX device was significantly stiffer than external fixation (P = 0.017) at the symphysis pubis. There was no significant difference in SI joint displacement between any of the groups. Anterior plate fixation is stiffer than both the INFIX and external fixation in single stance pelvic fracture model. The INFIX was stiffer than external fixation for both overall axial stiffness, and stiffness at the pubic symphysis. Combined with the presumed benefit of minimizing the complications associated with external fixation, the INFIX may be a more preferable option for temporary anterior pelvic fixation in situations where external fixation may have otherwise been used.

  7. Real-time recording and classification of eye movements in an immersive virtual environment.

    Science.gov (United States)

    Diaz, Gabriel; Cooper, Joseph; Kit, Dmitry; Hayhoe, Mary

    2013-10-10

    Despite the growing popularity of virtual reality environments, few laboratories are equipped to investigate eye movements within these environments. This primer is intended to reduce the time and effort required to incorporate eye-tracking equipment into a virtual reality environment. We discuss issues related to the initial startup and provide algorithms necessary for basic analysis. Algorithms are provided for the calculation of gaze angle within a virtual world using a monocular eye-tracker in a three-dimensional environment. In addition, we provide algorithms for the calculation of the angular distance between the gaze and a relevant virtual object and for the identification of fixations, saccades, and pursuit eye movements. Finally, we provide tools that temporally synchronize gaze data and the visual stimulus and enable real-time assembly of a video-based record of the experiment using the Quicktime MOV format, available at http://sourceforge.net/p/utdvrlibraries/. This record contains the visual stimulus, the gaze cursor, and associated numerical data and can be used for data exportation, visual inspection, and validation of calculated gaze movements.

  8. Surgical removal of eyes in a tertiary institution in North eastern ...

    African Journals Online (AJOL)

    Background Surgical eye removal is performed for various end-stage eye diseases to provide adequate comfort, replace volume and give good functional and cosmetic appearance. The pattern of eye removal is unknown for North Eastern Nigeria. Objective To determine the indications for eye removal in the study ...

  9. [Long-term efficacy of open reduction and internal fixation versus external fixation for unstable distal radius fractures: a meta-analysis].

    Science.gov (United States)

    Yang, Z; Yuan, Z Z; Ma, J X; Ma, X L

    2017-11-07

    Objective: To make a systematic assessment of the Long-term efficacy of open reduction and internal fixation versus external fixation for unstable distal radius fractures. Methods: A computer-based online search of PubMed, ScienceDirect, EMBASE, BIOSIS, Springer and Cochrane Library were performed. The randomized and controlled trials of open reduction and internal fixation versus external fixation for unstable distal radius fractures were collected. The included trials were screened out strictly based on the criterion of inclusion and exclusion. The quality of included trials was evaluated. RevMan 5.0 was used for data analysis. Results: Sixteen studies involving 1 268 patients were included. There were 618 patients with open reduction and internal fixation and 650 with external fixation. The results of meta-analysis indicated that there were statistically significant differences with regard to the complications postoperatively (infection( I (2)=0%, RR =0.27, 95% CI 0.16-0.45, Z =4.92, P internal fixation and external fixation are effective treatment for unstable distal radius fractures. Compared with external fixation, open reduction and internal fixation provides reduced complications postoperatively, lower DASH scores and better restoration of volar tilt for treatment of distal radius fractures.

  10. Dinitrogen fixation in aphotic oxygenated marine environments

    Directory of Open Access Journals (Sweden)

    Eyal eRahav

    2013-08-01

    Full Text Available We measured N2 fixation rates from oceanic zones that have traditionally been ignored as sources of biological N2 fixation; the aphotic, fully oxygenated, nitrate (NO3--rich, waters of the oligotrophic Levantine Basin (LB and the Gulf of Aqaba (GA. N2 fixation rates measured from pelagic aphotic waters to depths up to 720 m, during the mixed and stratified periods, ranged from 0.01 nmol N L-1 d-1 to 0.38 nmol N L-1 d-1. N2 fixation rates correlated significantly with bacterial productivity and heterotrophic diazotrophs were identified from aphotic as well as photic depths. Dissolved free amino acid amendments to whole water from the GA enhanced bacterial productivity by 2to 3.5 and N2 fixation rates by ~ 2 fold in samples collected from aphotic depths while in amendments to water from photic depths bacterial productivity increased 2 to 6 fold while N2 fixation rates increased by a factor of 2 to 4 illustrating that both BP an heterotrophic N2 fixation are carbon limited. Experimental manipulations of aphotic waters from the LB demonstrated a significant positive correlation between transparent exopolymeric particles (TEP concentration and N2 fixation rates. This suggests that sinking organic material and high carbon (C: nitrogen (N micro-environments (such as TEP-based aggregates or marine snow could support high heterotrophic N2 fixation rates in oxygenated surface waters and in the aphotic zones. Indeed, our calculations show that aphotic N2 fixation accounted for 37 to 75 % of the total daily integrated N2 fixation rates at both locations in the Mediterranean and Red Seas with rates equal or greater to those measured from the photic layers. Moreover, our results indicate that that while N2 fixation may be limited in the surface waters, aphotic, pelagic N2 fixation may contribute significantly to new N inputs in other oligotrophic basins, yet it is currently not included in regional or global N budgets.

  11. [Effectiveness comparison of flexible fixation and rigid fixation in treatment of ankle pronation-external rotation fractures with distal tibiofibular syndesmosis].

    Science.gov (United States)

    Li, Yuewei; Zhang, Minghui; Li, Xiaorong; Chen, Xiaoyong; Deng, Jianlong

    2017-07-01

    To compare the effectiveness of flexible fixation and rigid fixation in the treatment of ankle pronation-external rotation fractures with distal tibiofibular syndesmosis. A retrospective analysis was made on the clinical data of 50 patients with ankle pronation-external rotation fractures and distal tibiofibular syndesmosis treated between January 2013 and December 2015. Suture-button fixation was used in 23 patients (flexible fixation group) and cortical screw fixation in 27 patients (rigid fixation group). There was no significant difference in age, gender, weight, side, fracture type, and time from trauma to surgery between 2 groups ( P >0.05). The operation time, medial clear space (MCS), tibiofibular clear space (TFCS), tibiofibular overlap (TFO), American Orthopaedic Foot and Ankle Society (AOFAS) score, and Foot and Ankle Disability Index (FADI) score were compared between 2 groups. The operation time was (83.0±9.1) minutes in the flexible fixation group and was (79.6±13.1) minutes in the rigid fixation group, showing no significant difference ( t =1.052, P =0.265). All patients achieved healing of incision by first intention. The patients were followed up 12-20 months (mean, 14 months). The X-ray films showed good healing of fracture in 2 groups. There was no screw fracture, delayed union or nounion. The fracture healing time was (12.1±2.5) months in the flexible fixation group and was (11.3±3.2) months in the rigid fixation group, showing no significant difference between 2 groups ( t =1.024, P =0.192). Reduction loss occurred after removal of screw in 2 cases of the rigid fixation group. At last follow-up, there was no significant difference in MCS, TFCS, TFO, AOFAS score and FADI score between 2 groups ( P >0.05). Suture-button fixation has similar effectiveness to screw fixation in ankle function and imaging findings, and flexible fixation has lower risk of reduction loss of distal tibiofibular syndesmosis than rigid fixation.

  12. Eye tracking to evaluate evidence recognition in crime scene investigations.

    Science.gov (United States)

    Watalingam, Renuka Devi; Richetelli, Nicole; Pelz, Jeff B; Speir, Jacqueline A

    2017-11-01

    Crime scene analysts are the core of criminal investigations; decisions made at the scene greatly affect the speed of analysis and the quality of conclusions, thereby directly impacting the successful resolution of a case. If an examiner fails to recognize the pertinence of an item on scene, the analyst's theory regarding the crime will be limited. Conversely, unselective evidence collection will most likely include irrelevant material, thus increasing a forensic laboratory's backlog and potentially sending the investigation into an unproductive and costly direction. Therefore, it is critical that analysts recognize and properly evaluate forensic evidence that can assess the relative support of differing hypotheses related to event reconstruction. With this in mind, the aim of this study was to determine if quantitative eye tracking data and qualitative reconstruction accuracy could be used to distinguish investigator expertise. In order to assess this, 32 participants were successfully recruited and categorized as experts or trained novices based on their practical experiences and educational backgrounds. Each volunteer then processed a mock crime scene while wearing a mobile eye tracker, wherein visual fixations, durations, search patterns, and reconstruction accuracy were evaluated. The eye tracking data (dwell time and task percentage on areas of interest or AOIs) were compared using Earth Mover's Distance (EMD) and the Needleman-Wunsch (N-W) algorithm, revealing significant group differences for both search duration (EMD), as well as search sequence (N-W). More specifically, experts exhibited greater dissimilarity in search duration, but greater similarity in search sequences than their novice counterparts. In addition to the quantitative visual assessment of examiner variability, each participant's reconstruction skill was assessed using a 22-point binary scoring system, in which significant group differences were detected as a function of total

  13. Endoscopic forehead lift in patients with male pattern baldness.

    Science.gov (United States)

    Shipchandler, Taha Z; Sultan, Babar; Byrne, Patrick J

    2012-01-01

    The presence of male pattern baldness poses a significant challenge when attempting to optimize treatment of the upper third of the face. The purpose of this study is to demonstrate and discuss results of the endoscopic forehead lift in patients with male pattern baldness. This was a retrospective case series done in an academic medical center. Eleven patients with male pattern baldness (Norwood class IV-VII) underwent endoscopic forehead lift for forehead creases and brow ptosis. All patients achieved smoothing of the forehead and elevation of the brow with no scalp anesthesia at 1 month postoperatively. All patients were pleased with the healing of their incisions in midline, paramedian, and temporal regions. Alloplastic fixation devices used were visible postoperatively in 2 patients initially. The endoscopic forehead lift is a suitable approach for treating the upper third of the face in the presence of male pattern baldness. The use of alloplastic fixation devices may be used in this patient population, but other fixation methods should be considered. Copyright © 2012 Elsevier Inc. All rights reserved.

  14. EyeFrame: Real-time memory aid improves human multitasking via domain-general eye tracking procedures

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    P. eTaylor

    2015-09-01

    Full Text Available OBJECTIVE: We developed an extensively general closed-loop system to improve human interaction in various multitasking scenarios, with semi-autonomous agents, processes, and robots. BACKGROUND: Much technology is converging toward semi-independent processes with intermittent human supervision distributed over multiple computerized agents. Human operators multitask notoriously poorly, in part due to cognitive load and limited working memory. To multitask optimally, users must remember task order, e.g., the most neglected task, since longer times not monitoring an element indicates greater probability of need for user input. The secondary task of monitoring attention history over multiple spatial tasks requires similar cognitive resources as primary tasks themselves. Humans can not reliably make more than ~2 decisions/s. METHODS: Participants managed a range of 4-10 semi-autonomous agents performing rescue tasks. To optimize monitoring and controlling multiple agents, we created an automated short term memory aid, providing visual cues from users' gaze history. Cues indicated when and where to look next, and were derived from an inverse of eye fixation recency. RESULTS: Contingent eye tracking algorithms drastically improved operator performance, increasing multitasking capacity. The gaze aid reduced biases, and reduced cognitive load, measured by smaller pupil dilation. CONCLUSIONS: Our eye aid likely helped by delegating short-term memory to the computer, and by reducing decision making load. Past studies used eye position for gaze-aware control and interactive updating of displays in application-specific scenarios, but ours is the first to successfully implement domain-general algorithms. Procedures should generalize well to: process control, factory operations, robot control, surveillance, aviation, air traffic control, driving, military, mobile search and rescue, and many tasks where probability of utility is predicted by duration since last

  15. The eye movements of dyslexic children during reading and visual search: impact of the visual attention span.

    Science.gov (United States)

    Prado, Chloé; Dubois, Matthieu; Valdois, Sylviane

    2007-09-01

    The eye movements of 14 French dyslexic children having a VA span reduction and 14 normal readers were compared in two tasks of visual search and text reading. The dyslexic participants made a higher number of rightward fixations in reading only. They simultaneously processed the same low number of letters in both tasks whereas normal readers processed far more letters in reading. Importantly, the children's VA span abilities related to the number of letters simultaneously processed in reading. The atypical eye movements of some dyslexic readers in reading thus appear to reflect difficulties to increase their VA span according to the task request.

  16. Investigating the causes of wrap-up effects: evidence from eye movements and E-Z Reader.

    Science.gov (United States)

    Warren, Tessa; White, Sarah J; Reichle, Erik D

    2009-04-01

    Wrap-up effects in reading have traditionally been thought to reflect increased processing associated with intra- and inter-clause integration (Just, M. A. & Carpenter, P. A. (1980). A theory of reading: From eye fixations to comprehension. Psychological Review,87(4), 329-354; Rayner, K., Kambe, G., & Duffy, S. A. (2000). The effect of clause wrap-up on eye movements during reading. The Quarterly Journal of Experimental Psychology,53A(4), 1061-1080; cf. Hirotani, M., Frazier, L., & Rayner, K. (2006). Punctuation and intonation effects on clause and sentence wrap-up: Evidence from eye movements. Journal of Memory and Language,54, 425-443). We report an eye-tracking experiment with a strong manipulation of integrative complexity at a critical word that was either sentence-final, ended a comma-marked clause, or was not comma-marked. Although both complexity and punctuation had reliable effects, they did not interact in any eye-movement measure. These results as well as simulations using the E-Z Reader model of eye-movement control (Reichle, E. D., Warren, T., & McConnell, K. (2009). Using E-Z Reader to model the effects of higher-level language processing on eye movements during reading. Psychonomic Bulletin & Review,16(1), 1-20) suggest that traditional accounts of clause wrap-up are incomplete.

  17. Permanganate Fixation of Plant Cells

    Science.gov (United States)

    Mollenhauer, Hilton H.

    1959-01-01

    In an evaluation of procedures explored to circumvent some of the problems of osmium tetroxide-fixation and methacrylate embedding of plant materials, excised segments of root tips of Zea mays were fixed for electron microscopy in potassium permanganate in the following treatment variations: unbuffered and veronal-acetate buffered solutions of 0.6, 2.0, and 5.0 per cent KMnO4 at pH 5.0, 6.0, 6.7, and 7.5, and temperatures of 2–4°C. and 22°C. After fixation the segments were dehydrated, embedded in epoxy resin, sectioned, and observed or photographed. The cells of the central region of the rootcap are described. The fixation procedures employing unbuffered solutions containing 2.0 to 5.0 per cent KMnO4 at a temperature of 22°C. gave particularly good preservation of cell structure and all membrane systems. Similar results were obtained using a solution containing 2.0 per cent KMnO4, buffered with veronal-acetate to pH 6.0, and a fixation time of 2 hours at 22°C. The fixation procedure utilizing veronal-acetate buffered, 0.6 per cent KMnO4 at 2–4°C. and pH 6.7 also gave relatively good preservation of most cellular constituents. However, preservation of the plasma membrane was not so good, nor was the intensity of staining so great, as that with the group of fixatives containing greater concentrations of KMnO4. The other fixation procedures did not give satisfactory preservation of fine structure. A comparison is made of cell structures as fixed in KMnO4 or OsO4. PMID:14423414

  18. Task-irrelevant expectation violations in sequential manual actions: Evidence for a “check-after-surprise” mode of visual attention and eye-hand decoupling

    Directory of Open Access Journals (Sweden)

    Rebecca Martina Foerster

    2016-11-01

    Full Text Available When performing sequential manual actions (e.g., cooking, visual information is prioritized according to the task determining where and when to attend, look, and act. In well-practiced sequential actions, long-term memory (LTM-based expectations specify which action targets might be found where and when. We have previously demonstrated (Foerster and Schneider, 2015b that violations of such expectations that are task-relevant (e.g., target location change cause a regression from a memory-based mode of attentional selection to visual search. How might task-irrelevant expectation violations in such well-practiced sequential manual actions modify attentional selection? This question was investigated by a computerized version of the number-connection test. Participants clicked on nine spatially-distributed numbered target circles in ascending order while eye movements were recorded as proxy for covert attention. Target’s visual features and locations stayed constant for 65 prechange-trials, allowing practicing the manual action sequence. Consecutively, a task-irrelevant expectation violation occurred and stayed for 20 change-trials. Specifically, action target number 4 appeared in a different font. In 15 reversion-trials, number 4 returned to the original font. During the first task-irrelevant change trial, manual clicking was slower and eye scanpaths were larger and contained more fixations. The additional fixations were mainly checking fixations on the changed target while acting on later targets. Whereas the eyes repeatedly revisited the task-irrelevant change, cursor-paths remained completely unaffected. Effects lasted for 2-3 change trials and did not reappear during reversion. In conclusion, an unexpected task-irrelevant change on a task-defining feature of a well-practiced manual sequence leads to eye-hand decoupling and a check-after-surprise mode of attentional selection.

  19. Fundus autofluorescence patterns in primary intraocular lymphoma.

    Science.gov (United States)

    Casady, Megan; Faia, Lisa; Nazemzadeh, Maryam; Nussenblatt, Robert; Chan, Chi-Chao; Sen, H Nida

    2014-02-01

    To evaluate fundus autofluorescence (FAF) patterns in patients with primary intraocular (vitreoretinal) lymphoma. Records of all patients with primary intraocular lymphoma who underwent FAF imaging at the National Eye Institute were reviewed. Fundus autofluorescence patterns were evaluated with respect to clinical disease status and the findings on fluorescein angiography and spectral-domain optical coherence tomography. There were 18 eyes (10 patients) with primary intraocular lymphoma that underwent FAF imaging. Abnormal autofluorescence in the form of granular hyperautofluorescence and hypoautofluorescence was seen in 11 eyes (61%), and blockage by mass lesion was seen in 2 eyes (11%). All eyes with granular pattern on FAF had active primary intraocular lymphoma at the time of imaging, but there were 5 eyes with unremarkable FAF, which were found to have active lymphoma. The most common pattern on fluorescein angiography was hypofluorescent round spots with a "leopard spot" appearance (43%). These hypofluorescent spots on fluorescein angiography correlated with hyperautofluorescent spots on FAF in 5 eyes (36%) (inversion of FAF). Nodular hyperreflective spots at the level of retinal pigment epithelium on optical coherence tomography were noted in 43% of eyes. The hyperautofluorescent spots on FAF correlated with nodular hyperreflective spots on optical coherence tomography in 6 eyes (43%). Granularity on FAF was associated with active lymphoma in majority of the cases. An inversion of FAF (hyperautofluorescent spots on FAF corresponding to hypofluorescent spots on fluorescein angiography) was observed in less than half of the eyes.

  20. Influence of gap and overlap paradigms on saccade latencies and vergence eye movements in seven-year-old children.

    Science.gov (United States)

    Bucci, Maria Pia; Pouvreau, Nathalie; Yang, Qing; Kapoula, Zoï

    2005-07-01

    The latency of eye movements is influenced by the fixation task; when the fixation stimulus is switched off before the target presentation (gap paradigm) the latency becomes short and express movements occur. In contrast, when the fixation stimulus remains on when the target appears (overlap paradigm), eye movement latency is longer. Several previous studies have shown increased rates of express saccades in children; however the presence of an express type of latency for vergence and combined movements in children has never been explored. The present study examines the effects of the gap and the overlap paradigms on horizontal saccades at far (150 cm) and at close (20 cm) viewing distances, on vergence along the median plane, and on saccades combined with convergence or divergence in 15 normal seven-year-old children. The results show that the gap paradigm produced shorter latency for all eye movements than the overlap paradigm, but the difference was only significant for saccades at close viewing distances, for divergence (pure and combined), and for saccades combined with vergence. The gap paradigm produced significantly higher rates of express latencies for saccades at close viewing distances, for divergence, and for saccades combined with divergence; in contrast, the frequencies of express latencies for saccades at far viewing distances and for convergence (pure or combined) were similar in the gap and the overlap paradigms. Interestingly, the rate of anticipatory latencies (gap paradigm. Our collective findings suggest that the initiation of saccades at close viewing distances and of divergence is more reflexive, particularly in the gap paradigm. The finding of frequent anticipatory divergence that occurs at similar rates for seven-year-old children (this study) and for adults (Coubard et al., 2004, Exp Brain Res 154:368-381) indicates that predictive initiation of divergence is dominant.

  1. How strongly do word reading times and lexical decision times correlate? Combining data from eye movement corpora and megastudies.

    Science.gov (United States)

    Kuperman, Victor; Drieghe, Denis; Keuleers, Emmanuel; Brysbaert, Marc

    2013-01-01

    We assess the amount of shared variance between three measures of visual word recognition latencies: eye movement latencies, lexical decision times, and naming times. After partialling out the effects of word frequency and word length, two well-documented predictors of word recognition latencies, we see that 7-44% of the variance is uniquely shared between lexical decision times and naming times, depending on the frequency range of the words used. A similar analysis of eye movement latencies shows that the percentage of variance they uniquely share either with lexical decision times or with naming times is much lower. It is 5-17% for gaze durations and lexical decision times in studies with target words presented in neutral sentences, but drops to 0.2% for corpus studies in which eye movements to all words are analysed. Correlations between gaze durations and naming latencies are lower still. These findings suggest that processing times in isolated word processing and continuous text reading are affected by specific task demands and presentation format, and that lexical decision times and naming times are not very informative in predicting eye movement latencies in text reading once the effect of word frequency and word length are taken into account. The difference between controlled experiments and natural reading suggests that reading strategies and stimulus materials may determine the degree to which the immediacy-of-processing assumption and the eye-mind assumption apply. Fixation times are more likely to exclusively reflect the lexical processing of the currently fixated word in controlled studies with unpredictable target words rather than in natural reading of sentences or texts.

  2. Strain-stress analysis of lower limb with applied fixator

    Directory of Open Access Journals (Sweden)

    Mrázek M.

    2010-07-01

    Full Text Available This paper compares physiological state of tibia before and after application of an external fixator. The fixator systems’ models but also model of tibia are loaded in the direction of body axis. The paper is focused on the examination of differences in stiffness before and after the application of fixation. Two types of axial external fixators are compared. Both fixators differ in their construction. The first fixator is two-frame and fixation rods are used for fixing the bone tissue (variant I. The second one is fixed into tibia with screws (variant II. We have found out that the two-frame external fixator has much bigger stiffness during limb fixation than the fixator with one body. Much higher deformations compared to physiological state of tibia occur in the variant II.

  3. Comparison of a modified mid-coronal sectioning technique and Wilson's technique when conducting eye and brain examinations in rabbit teratology studies.

    Science.gov (United States)

    Ziejewski, Mary K; Solomon, Howard M; Rendemonti, Joyce; Stanislaus, Dinesh

    2015-02-01

    There are two methods used when examining fetal rabbit eyes and brain in teratology studies. One method employs prior fixation before serial sectioning (Wilson's technique) and the other uses fresh tissue (mid-coronal sectioning). We modified the mid-coronal sectioning technique to include removal of eyes and brain for closer examination and to increase the number of structures that can be evaluated and compared it to the Wilson's technique. We found that external examination of the head, in conjunction with either sectioning method, is equally sensitive in identifying developmental defects. We evaluated 40,401 New Zealand White (NZW) and Dutch-Belted (DB) rabbit fetuses for external head alterations, of which 28,538 fetuses were further examined for eye and brain alterations using the modified mid-coronal sectioning method (16,675 fetuses) or Wilson's technique (11,863 fetuses). The fetuses were from vehicle control or drug-treated pregnant rabbits in embryo-fetal development studies conducted to meet international regulatory requirements for the development of new drugs. Both methods detected the more common alterations (microphthalmia and dilated lateral cerebral ventricles) and other less common findings (changes in size and/or shape of eye and brain structures). While both methods are equally sensitive at detecting common and rare developmental defects, the modified mid-coronal sectioning technique eliminates the use of chemicals and concomitant fixation artifacts that occur with the Wilson's technique and allows for examination of 100% intact fetuses thereby increasing potential for detecting eye and brain alterations as these findings occur infrequently in rabbits. © 2015 Wiley Periodicals, Inc.

  4. The influence of action video game playing on eye movement behaviour during visual search in abstract, in-game and natural scenes.

    Science.gov (United States)

    Azizi, Elham; Abel, Larry A; Stainer, Matthew J

    2017-02-01

    Action game playing has been associated with several improvements in visual attention tasks. However, it is not clear how such changes might influence the way we overtly select information from our visual world (i.e. eye movements). We examined whether action-video-game training changed eye movement behaviour in a series of visual search tasks including conjunctive search (relatively abstracted from natural behaviour), game-related search, and more naturalistic scene search. Forty nongamers were trained in either an action first-person shooter game or a card game (control) for 10 hours. As a further control, we recorded eye movements of 20 experienced action gamers on the same tasks. The results did not show any change in duration of fixations or saccade amplitude either from before to after the training or between all nongamers (pretraining) and experienced action gamers. However, we observed a change in search strategy, reflected by a reduction in the vertical distribution of fixations for the game-related search task in the action-game-trained group. This might suggest learning the likely distribution of targets. In other words, game training only skilled participants to search game images for targets important to the game, with no indication of transfer to the more natural scene search. Taken together, these results suggest no modification in overt allocation of attention. Either the skills that can be trained with action gaming are not powerful enough to influence information selection through eye movements, or action-game-learned skills are not used when deciding where to move the eyes.

  5. Can Operator's Thought Be Inferred from Eye Movement Data?

    International Nuclear Information System (INIS)

    Ha, Jun Su; Seong, Poong Hyun

    2010-01-01

    Correct situation awareness (SA) has been considered a crucial key to improving performance and reducing error in NPPs. There are a lot of information sources that should be monitored in nuclear power plants (NPPs), but operators have only limited capacity of attention and memory. Operators in NPPs selectively attend to important information sources to effectively develop SA when an abnormal or accidental situation occurs. Selective attention to important information sources is continued while maintaining SA as well. The authors have developed measures of attentional resource effectiveness in information searching such as FIR (Fixation to Importance Ratio) and SAE (Selective Attention Effectiveness) which represent how effectively an operator attends to important information sources. The FIR is the ratio of attentional resources (i.e. the number and the duration of eye fixations) spent on an information source to the importance of the information source as follows: Theoretically, the SAE should approach to zero for the best effectiveness. The underlying principle of the measures is that information sources should be selectively attended to according to their informational importance. The importance of information sources depends on the state of a NPP. For example, the importance of the pressurizer level for loss of coolant accident (LOCA) is different from that for steam line break (SLB). Hence, sets of importance for information sources should be evaluated for all possible events. The FIR and the SAE have also been used as performance measures in a HMI evaluation method named 'DEMIS (Difficulty Evaluation Method in Information Searching). In this study, Operator's thought is inferred with the eye movement data during complex diagnostic tasks in NPPs. SAEs are calculated with the eye movement data for all possible events (e.g., accident, incident, or transient) in NPPs. Inference of operator thought is made by analyzing the calculated SAEs. Theoretically, the event

  6. Measurement of the wave-front aberration of the eye by a fast psychophysical procedure

    International Nuclear Information System (INIS)

    He, J.C.; Marcos, S.; Webb, R.H.; Burns, S.A.

    1998-01-01

    We used a fast psychophysical procedure to determine the wave-front aberrations of the human eye in vivo. We measured the angular deviation of light rays entering the eye at different pupillary locations by aligning an image of a point source entering the pupil at different locations to the image of a fixation cross entering the pupil at a fixed location. We fitted the data to a Zernike series to reconstruct the wave-front aberrations of the pupil. With this technique the repeatability of the measurement of the individual coefficients was 0.019 μm. The standard deviation of the overall wave-height estimation across the pupil is less than 0.3 μm. Since this technique does not require the administration of pharmacological agents to dilate the pupil, we were able to measure the changes in the aberrations of the eye during accommodation. We found that administration of even a mild dilating agent causes a change in the aberration structure of the eye. copyright 1998 Optical Society of America

  7. Fixation of displaced subcapital femoral fractures. Compression screw fixation versus double divergent pins.

    Science.gov (United States)

    Christie, J; Howie, C R; Armour, P C

    1988-03-01

    One hundred and twenty-seven consecutive patients with displaced subcapital fractures of the femoral neck (Garden Grade III or IV) all under 80 years of age and independently mobile, were randomly allocated to fixation with either double divergent pins or a single sliding screw-plate device. The incidence of non-union and infection in the sliding screw-plate group was significantly higher, and we believe that when internal fixation is considered appropriate multiple pinning should be used. Mobility after treatment was disappointing in about half of the patients, and we feel that internal fixation can only be justified in patients who are physiologically well preserved and who maintain a high level of activity.

  8. A tropical horde of counterfeit predator eyes.

    Science.gov (United States)

    Janzen, Daniel H; Hallwachs, Winnie; Burns, John M

    2010-06-29

    We propose that the many different, but essentially similar, eye-like and face-like color patterns displayed by hundreds of species of tropical caterpillars and pupae-26 examples of which are displayed here from the dry, cloud, and rain forests of Area de Conservacion Guanacaste (ACG) in northwestern Costa Rica-constitute a huge and pervasive mimicry complex that is evolutionarily generated and sustained by the survival behavior of a large and multispecific array of potential predators: the insect-eating birds. We propose that these predators are variously and innately programmed to flee when abruptly confronted, at close range, with what appears to be an eye of one of their predators. Such a mimetic complex differs from various classical Batesian and Müllerian mimicry complexes of adult butterflies in that (i) the predators sustain it for the most part by innate traits rather than by avoidance behavior learned through disagreeable experiences, (ii) the more or less harmless, sessile, and largely edible mimics vastly outnumber the models, and (iii) there is no particular selection for the eye-like color pattern to closely mimic the eye or face of any particular predator of the insect-eating birds or that of any other member of this mimicry complex. Indeed, selection may not favor exact resemblance among these mimics at all. Such convergence through selection could create a superabundance of one particular false eyespot or face pattern, thereby increasing the likelihood of a bird species or guild learning to associate that pattern with harmless prey.

  9. Grammatical number processing and anticipatory eye movements are not tightly coordinated in English spoken language comprehension

    Directory of Open Access Journals (Sweden)

    Brian eRiordan

    2015-05-01

    Full Text Available Recent studies of eye movements in world-situated language comprehension have demonstrated that rapid processing of morphosyntactic information – e.g., grammatical gender and number marking – can produce anticipatory eye movements to referents in the visual scene. We investigated how type of morphosyntactic information and the goals of language users in comprehension affected eye movements, focusing on the processing of grammatical number morphology in English-speaking adults. Participants’ eye movements were recorded as they listened to simple English declarative (There are the lions. and interrogative (Where are the lions? sentences. In Experiment 1, no differences were observed in speed to fixate target referents when grammatical number information was informative relative to when it was not. The same result was obtained in a speeded task (Experiment 2 and in a task using mixed sentence types (Experiment 3. We conclude that grammatical number processing in English and eye movements to potential referents are not tightly coordinated. These results suggest limits on the role of predictive eye movements in concurrent linguistic and scene processing. We discuss how these results can inform and constrain predictive approaches to language processing.

  10. External fixation using locking plate in distal tibial fracture: a finite element analysis.

    Science.gov (United States)

    Zhang, Jingwei; Ebraheim, Nabil; Li, Ming; He, Xianfeng; Schwind, Joshua; Liu, Jiayong; Zhu, Limei

    2015-08-01

    External fixation of tibial fractures using a locking plate has been reported with favorable results in some selected patients. However, the stability of external plate fixation in this fracture pattern has not been previously demonstrated. We investigated the stability of external plate fixation with different plate-bone distances. In this study, the computational processing model of external fixation of a distal tibial metaphyseal fracture utilizing the contralateral femoral less invasive stabilization system plate was analyzed. The plate was placed on the anteromedial aspect of tibia with different plate-bone distances: 1, 10, 20, and 30 mm. Under axial load, the stiffness of construct in all groups was higher than intact tibia. Under axial load with an internal rotational force, the stiffness of construct with 1 and 10 mm plate-bone distances was similar to that of an intact tibia and the stiffness of the construct with 20 and 30 mm distances was lower than that of an intact tibia. Under axial load with an external rotational force, the stiffness of the construct in all groups was lower than that of an intact tibia. The maximum plate stresses were concentrated at the two most distal screws and were highest in the construct with the 10 mm plate-bone distance, and least in the construct with a 1 mm plate-bone distance. To guarantee a stable external plate fixation in distal tibial fracture, the plate-bone distance should be less than 30 mm.

  11. Owl's eye appearance: a case report

    International Nuclear Information System (INIS)

    Mathur, Mukul; Asha, P.

    2010-01-01

    Full text: Hyper-functioning thyroid nodule may present various scintigraphic appearances on thyroid scans. Autonomously hyper functioning thyroid nodules often show degenerative changes. These changes may give rise to peripheral photopenic areas on a thyroid scan. In this report we present a case of hyper functioning nodule showing appearance of an owl's eye. Although rare, such pattern can be seen in a variety of benign and malignant thyroid conditions. A 42-year-old man presented with a solitary thyroid nodule in the right lobe and weight loss for four months. The thyroid hormone profile confirmed hyperthyroidism. Thyroid function testing revealed T4=136.8 nmol/l (Normal = 66.0-181.0 nmol/L) and Thyroid Stimulating Hormone (TSH) = 0.283 (Normal =0.27- 4.2 μIU/ml). Antithyroglobulin antibodies and antimicrosmal antibodies were negative. The patient was referred for thyroid scan and uptake. A Thyroid scan was obtained after the intravenous injection of 5 mCi (185MBq) of 99m Tc pertechnetate. Anterior view obtained using a parallel hole collimator. The scan showed peripheral photopenic area with a central focal area of increased uptake giving the appearance of 'Owl's eye'. 99m Tc-pertechnetate uptake was increased. A scintigraphic 'Owl's eye' sign has been described in thyroid cyst, benign autonomous nodule and papillary carcinoma of the thyroid gland. This Owl's eye pattern appears to be caused by a focus of functioning tissue overlapping a large cold area in a nodule that has cystic,degenerative and necrotic changes in the middle of a benign and malignant pathology. Hyper functioning nodules may scintigraphically show Owl's eye pattern due to intra nodular degeneration, with residual hyper functioning tissue within or overlapping the degenerative area

  12. Aquaporins 6-12 in the human eye

    DEFF Research Database (Denmark)

    Tran, Thuy Linh; Bek, Toke; Holm, Lars

    2012-01-01

    Purpose: Aquaporins (AQPs) are widely expressed and have diverse distribution patterns in the eye. AQPs 0-5 have been localized at the cellular level in human eyes. We investigated the presence of the more recently discovered AQPs 6-12 in the human eye. Methods: RT-PCR was performed on fresh tissue...... from two human eyes divided into the cornea, corneal limbus, ciliary body and iris, lens, choroid, optic nerve, retina and sclera. Each structure was examined to detect the mRNA of AQPs 6-12. Twenty-one human eyes were examined using immunohistochemical and immunofluorescence techniques to determine...... was detected in the corneal epithelium, corneal endothelium, trabecular meshwork endothelium, ciliary epithelia, lens epithelium, the inner and outer limiting membrane of the retina, the retinal pigment epithelium and the capillary endothelium of all parts of the eye. AQP9 immunolabelling was detected...

  13. Preliminary Experience Using Eye-Tracking Technology to Differentiate Novice and Expert Image Interpretation for Ultrasound-Guided Regional Anesthesia.

    Science.gov (United States)

    Borg, Lindsay K; Harrison, T Kyle; Kou, Alex; Mariano, Edward R; Udani, Ankeet D; Kim, T Edward; Shum, Cynthia; Howard, Steven K

    2018-02-01

    Objective measures are needed to guide the novice's pathway to expertise. Within and outside medicine, eye tracking has been used for both training and assessment. We designed this study to test the hypothesis that eye tracking may differentiate novices from experts in static image interpretation for ultrasound (US)-guided regional anesthesia. We recruited novice anesthesiology residents and regional anesthesiology experts. Participants wore eye-tracking glasses, were shown 5 sonograms of US-guided regional anesthesia, and were asked a series of anatomy-based questions related to each image while their eye movements were recorded. The answer to each question was a location on the sonogram, defined as the area of interest (AOI). The primary outcome was the total gaze time in the AOI (seconds). Secondary outcomes were the total gaze time outside the AOI (seconds), total time to answer (seconds), and time to first fixation on the AOI (seconds). Five novices and 5 experts completed the study. Although the gaze time (mean ± SD) in the AOI was not different between groups (7 ± 4 seconds for novices and 7 ± 3 seconds for experts; P = .150), the gaze time outside the AOI was greater for novices (75 ± 18 versus 44 ± 4 seconds for experts; P = .005). The total time to answer and total time to first fixation in the AOI were both shorter for experts. Experts in US-guided regional anesthesia take less time to identify sonoanatomy and spend less unfocused time away from a target compared to novices. Eye tracking is a potentially useful tool to differentiate novices from experts in the domain of US image interpretation. © 2017 by the American Institute of Ultrasound in Medicine.

  14. Flexible fixation and fracture healing

    DEFF Research Database (Denmark)

    Schmal, Hagen; Strohm, Peter C; Jaeger, Martin

    2011-01-01

    , noncomminuted fractures. External fixation uses external bars for stabilization, whereas internal fixation is realized by subcutaneous placement of locking plates. Both of these "biologic" osteosynthesis methods allow a minimally invasive approach and do not compromise fracture hematoma and periosteal blood...

  15. Photosynthate partitioning and nitrogen fixation of alfalfa and birdsfoot trefoil

    International Nuclear Information System (INIS)

    Shieh, W.J.

    1985-01-01

    Nodule mass and number are usually correlated with rates of nitrogen fixation in legumes. Birdsfoot trefoil (Lotus corniculatus L.) with more than twice the nodule number and mass, however, fixes far less nitrogen than alfalfa (Medicago sativa L.) at the same age. In this research, photosynthesis and photosynthate partitioning and utilization in relation to nitrogen fixation of alfalfa and birdsfoot trefoil were examined in order to determine their relationship to nitrogen fixation potential. Photosynthate to nodules was studied using 14 CO 2 labeling techniques. Partitioning patterns were altered by shading and dark depletion treatments. Efficiency of photosynthate utilization was examined by determining turnover of 14 C photosynthate in nodule metabolites and by studying rates of cyanide-resistant and cyanide-sensitive O 2 uptake. Alfalfa nodule activity was greater than trefoil expressed on a hole pot or nodule dry weight basis. Both shading and dark treatments significantly reduced nodule activity as estimated by the acetylene reduction assay. Shoots of both species were found to be the dominant sinks for photosynthate. Percentage 14 C recovered in alfalfa roots was more than twice that of trefoil at 1,2,3,4 and 24 h after labeling. Greater relative specific radioactivity (RSA) in nodules of both species suggests that they were stronger sinks for current photosynthate than roots

  16. [Extramedullary fixation combined with intramedullary fixation in the surgical reduction of sagittal mandibular condylar fractures].

    Science.gov (United States)

    Chuanjun, Chen; Xiaoyang, Chen; Jing, Chen

    2016-10-01

    This study aimed to evaluate the clinical effect of extramedullary fixation combined with intramedullary fixation during the surgical reduction of sagittal mandibular condylar fractures. Twenty-four sagittal fractures of the mandibular condyle in18 patients were fixed by two appliances: intramedullary with one long-screw osteosynthesis or Kirschner wire and extramedullary with one micro-plate. The radiologically-recorded post-operative stability-associated com-plications included the screw/micro-plate loosening, micro-plate twisting, micro-plate fractures, and fragment rotation. The occluding relations, the maximalinter-incisal distances upon mouth opening, and the mandibular deflection upon mouth opening were evaluated based on follow-up clinical examination. Postoperative panoramic X-ray and CT scans showed good repositioning of the fragment, with no redislocation or rotation, no screw/plate loosening, and no plate-twisting or fracture. Clinical examination showed that all patients regained normal mandibular movements, ideal occlusion, and normal maximal inter-incisal distances upon mouth opening. Extramedullary fixation combined with intramedullary fixation is highly recommended for sagittal condylar fractures because of the anti-rotation effect of the fragment and the reasonable place-ment of the fixation appliances.

  17. Regulation of Development and Nitrogen Fixation in Anabaena

    Energy Technology Data Exchange (ETDEWEB)

    James W. Golden

    2008-10-17

    The regulation of development and cellular differentiation is important for all multicellular organisms. The nitrogen-fixing filamentous cyanobacterium Anabaena (also Nostoc) sp. PCC 7120 (hereafter Anabaena) provides a model of multicellular microbial development and pattern formation. Anabaena reduces N2 to ammonia in specialized terminally differentiated cells called heterocysts. A one-dimensional developmental pattern of single heterocysts regularly spaced along filaments of photosynthetic vegetative cells is established to form a multicellular organism composed of these two interdependent cell types. This multicellular growth pattern, the distinct phylogeny of cyanobacteria, and the suspected antiquity of heterocyst development make this an important model system. Our long-term goal is to understand the regulatory network required for heterocyst development and nitrogen fixation. This project is focused on two key aspects of heterocyst regulation: one, the mechanism by which HetR controls the initiation of differentiation, and two, the cis and trans acting factors required for expression of the nitrogen-fixation (nif) genes. HetR is thought to be a central regulator of heterocyst development but the partners and mechanisms involved in this regulation are unknown. Our recent results indicate that PatS and other signals that regulate heterocyst pattern cannot interact, directly or indirectly, with a R223W mutant of HetR. We plan to use biochemical and genetic approaches to identify proteins that interact with the HetR protein, which will help reveal the mechanisms underlying its regulation of development. Our second goal is to determine how the nif genes are expressed. It is important to understand the mechanisms controlling nif genes since they represent the culmination of the differentiation process and the essence of heterocyst function. The Anabaena genome lacks the genes required for expression of nif genes present in other organisms such as rpoN (sigma 54

  18. Visual Saliency Prediction and Evaluation across Different Perceptual Tasks.

    Directory of Open Access Journals (Sweden)

    Shafin Rahman

    Full Text Available Saliency maps produced by different algorithms are often evaluated by comparing output to fixated image locations appearing in human eye tracking data. There are challenges in evaluation based on fixation data due to bias in the data. Properties of eye movement patterns that are independent of image content may limit the validity of evaluation results, including spatial bias in fixation data. To address this problem, we present modeling and evaluation results for data derived from different perceptual tasks related to the concept of saliency. We also present a novel approach to benchmarking to deal with some of the challenges posed by spatial bias. The results presented establish the value of alternatives to fixation data to drive improvement and development of models. We also demonstrate an approach to approximate the output of alternative perceptual tasks based on computational saliency and/or eye gaze data. As a whole, this work presents novel benchmarking results and methods, establishes a new performance baseline for perceptual tasks that provide an alternative window into visual saliency, and demonstrates the capacity for saliency to serve in approximating human behaviour for one visual task given data from another.

  19. Spectrum Of Eye Diseases At The Ebonyi State University Teaching ...

    African Journals Online (AJOL)

    Objective To determine the pattern of eye disorders presenting at the eye clinic of EBSUTH, Abakaliki. Methodology: This is a prospective, descriptive, total population study. The sample size consists of all consecutive new patients seen at the eye clinic over a 7- month period. A proforma developed for the study was used to ...

  20. Customizable rigid head fixation for infants: technical note.

    Science.gov (United States)

    Udayakumaran, Suhas; Onyia, Chiazor U

    2016-01-01

    The need and advantages of rigid fixation of the head in cranial surgeries are well documented (Berryhill et al., Otolaryngol Head Neck Surg 121:269-273, 1999). Head fixation for neurosurgical procedures in infants and in early years has been a challenge and is fraught with risk. Despite the fact that pediatric pins are designed, rigid head fixation involving direct application of pins to the head of infants and slightly older children is still generally not safe (Agrawal and Steinbok, Childs Nerv Syst 22:1473-1474, 2006). Yet, there are some surgeries in which some form of rigid fixation is required (Agrawal and Steinbok, Childs Nerv Syst 22:1473-1474, 2006). We describe a simple technique to achieve rigid fixation of the head in infants for neurosurgical procedures. This involves applying a head band made of Plaster of Paris (POP) around the head and then applying the fixation pins of the fixation frame directly on to the POP. We have used this technique of head fixation successfully for infants with no complications.

  1. Eye movements when reading sentences with handwritten words.

    Science.gov (United States)

    Perea, Manuel; Marcet, Ana; Uixera, Beatriz; Vergara-Martínez, Marta

    2016-10-17

    The examination of how we read handwritten words (i.e., the original form of writing) has typically been disregarded in the literature on reading. Previous research using word recognition tasks has shown that lexical effects (e.g., the word-frequency effect) are magnified when reading difficult handwritten words. To examine this issue in a more ecological scenario, we registered the participants' eye movements when reading handwritten sentences that varied in the degree of legibility (i.e., sentences composed of words in easy vs. difficult handwritten style). For comparison purposes, we included a condition with printed sentences. Results showed a larger reading cost for sentences with difficult handwritten words than for sentences with easy handwritten words, which in turn showed a reading cost relative to the sentences with printed words. Critically, the effect of word frequency was greater for difficult handwritten words than for easy handwritten words or printed words in the total times on a target word, but not on first-fixation durations or gaze durations. We examine the implications of these findings for models of eye movement control in reading.

  2. Pattern of Eye Diseases among Commercial Intercity Vehicle Drivers ...

    African Journals Online (AJOL)

    BOLA

    with a visual acuity (VA) of less than 3/60 in one eye. Cataract and ... to dry. Those found to require further assessment, refraction and surgery were referred to the UITH. The data .... Symptoms of ocular disease among the CIVDs examined.

  3. Morphology of the eye of the southern right whales (Eubalaena australis).

    Science.gov (United States)

    Buono, Mónica R; Fernández, Marta S; Herrera, Yanina

    2012-02-01

    Recently, there has been a growing interest in the anatomy and optics of the visual system of cetaceans. However, much of the new information has been focused on odontocetes, and relatively little is known about the visual anatomy of baleen whales. The aim of this study was describe the eye anatomy of the southern right whale (Eubalaena australis). Eye samples were collected from 26 calves, four adults with known body length, as well as two specimens of unknown body length that had stranded near their nursery ground at Península Valdés, Argentina, over 6 years. We provide anatomical descriptions of the eyeball and extraocular structures, as well as quantitative data in the form of eyeball, corneal, scleral, and lens measurements. To explore the sensitivity of the eye to light, the f-number was estimated in one specimen. We found that the eyes of the calves differed from those of the adults in having less periorbital fat surrounding the eyeball. We also observed variations in the abundance of periorbital fat among the adult specimens. The regression analysis revealed a correlation between body length and eyeball size. By contrast, the dimensions of the cornea were only weakly correlated with body length. The estimated f-number suggests that the optical sensitivity of the Eubalaena australis eye is relatively low. However, caution had to be taken in interpreting f-number as a proxy of eye sensitivity because it depends on the lens size, which can be affected by the fixation methods used. Copyright © 2011 Wiley Periodicals, Inc.

  4. Does the 'P300' speller depend on eye gaze?

    Science.gov (United States)

    Brunner, P.; Joshi, S.; Briskin, S.; Wolpaw, J. R.; Bischof, H.; Schalk, G.

    2010-10-01

    Many people affected by debilitating neuromuscular disorders such as amyotrophic lateral sclerosis, brainstem stroke or spinal cord injury are impaired in their ability to, or are even unable to, communicate. A brain-computer interface (BCI) uses brain signals, rather than muscles, to re-establish communication with the outside world. One particular BCI approach is the so-called 'P300 matrix speller' that was first described by Farwell and Donchin (1988 Electroencephalogr. Clin. Neurophysiol. 70 510-23). It has been widely assumed that this method does not depend on the ability to focus on the desired character, because it was thought that it relies primarily on the P300-evoked potential and minimally, if at all, on other EEG features such as the visual-evoked potential (VEP). This issue is highly relevant for the clinical application of this BCI method, because eye movements may be impaired or lost in the relevant user population. This study investigated the extent to which the performance in a 'P300' speller BCI depends on eye gaze. We evaluated the performance of 17 healthy subjects using a 'P300' matrix speller under two conditions. Under one condition ('letter'), the subjects focused their eye gaze on the intended letter, while under the second condition ('center'), the subjects focused their eye gaze on a fixation cross that was located in the center of the matrix. The results show that the performance of the 'P300' matrix speller in normal subjects depends in considerable measure on gaze direction. They thereby disprove a widespread assumption in BCI research, and suggest that this BCI might function more effectively for people who retain some eye-movement control. The applicability of these findings to people with severe neuromuscular disabilities (particularly in eye-movements) remains to be determined.

  5. Eye-Head Coordination in 31 Space Shuttle Astronauts during Visual Target Acquisition.

    Science.gov (United States)

    Reschke, Millard F; Kolev, Ognyan I; Clément, Gilles

    2017-10-27

    Between 1989 and 1995, NASA evaluated how increases in flight duration of up to 17 days affected the health and performance of Space Shuttle astronauts. Thirty-one Space Shuttle pilots participating in 17 space missions were tested at 3 different times before flight and 3 different times after flight, starting within a few hours of return to Earth. The astronauts moved their head and eyes as quickly as possible from the central fixation point to a specified target located 20°, 30°, or 60° off center. Eye movements were measured with electro-oculography (EOG). Head movements were measured with a triaxial rate sensor system mounted on a headband. The mean time to visually acquire the targets immediately after landing was 7-10% (30-34 ms) slower than mean preflight values, but results returned to baseline after 48 hours. This increase in gaze latency was due to a decrease in velocity and amplitude of both the eye saccade and head movement toward the target. Results were similar after all space missions, regardless of length.

  6. Applying the decision moving window to risky choice: Comparison of eye-tracking and mousetracing methods

    Directory of Open Access Journals (Sweden)

    Ana M. Franco-Watkins

    2011-12-01

    Full Text Available Currently, a disparity exists between the process-level models decision researchers use to describe and predict decision behavior and the methods implemented and metrics collected to test these models. The current work seeks to remedy this disparity by combining the advantages of work in decision research (mouse-tracing paradigms with contingent information display and cognitive psychology (eye-tracking paradigms from reading and scene perception. In particular, we introduce a new decision moving-window paradigm that presents stimulus information contingent on eye fixations. We provide data from the first application of this method to risky decision making, and show how it compares to basic eye-tracking and mouse-tracing methods. We also enumerate the practical, theoretical, and analytic advantages this method offers above and beyond both mouse-tracing with occlusion and basic eye tracking of information without occlusion. We include the use of new metrics that offer more precision than those typically calculated on mouse-tracing data as well as those not possible or feasible within the mouse-tracing paradigm.

  7. Eye Movement Patterns during Locomotion in Real-World and Simulated Environments

    Directory of Open Access Journals (Sweden)

    Ming Zhao

    2012-05-01

    Full Text Available Eye movements in a search-and-count walking task were compared between a simulated (SE and real-world environment (RE. Eye movements were recorded using the mobile WearCam in either RE or the StroMoHab locomotion simulator, a treadmill-based system for gait mobility rehabilitation. For Experiment 1, a RE was prepared with objects (coloured balls and occluding barriers placed along a 38 m long corridor. A video was captured from a walker's viewpoint at 1.3 km/hr. Fifteen subjects per environment reported the total object count after completing a walk while viewing the video in the SE (at 0, 1.3, or 2.5 km/h and RE (at 1.3 km/h. Examining the number of eye transitions (TotET between objects in relation to walking speed in SE, revealed significant increases between 0 and 2.5 km/h (F3, 56 =20.62, p = .02 and 1.3 and 2.5 km/h (F3, 56 =20.62, p = .039, despite no change in video speed; no significant difference was found between 0 and 1.3 km/h. In Experiment 2, 15 subjects viewed a static checkered screen and were instructed to ‘view the screen’ while walking. TotET decreased significantly, between 1.3 km/h and 5.2 km/h (F2, 27 =3.437, p = .014; no significant differences were observed between 2.6 km/h and either 1.3 km/h or 5.2 km/h. In real-world conditions, walking faster increases the difficulty of search tasks, with a likely correlated increase in eye movements. Apparently, the expectation of increased difficulty carries over to SE, even if the visual task is not more difficult. The findings point to physiological and perceptual correlations between locomotion and eye movements.

  8. Rhythmic Firing of Pedunculopontine Tegmental Nucleus Neurons in Monkeys during Eye Movement Task.

    Directory of Open Access Journals (Sweden)

    Ken-Ichi Okada

    Full Text Available The pedunculopontine tegmental nucleus (PPTN has been thought to be involved in the control of behavioral state. Projections to the entire thalamus and reciprocal connections with the basal ganglia nuclei suggest a potential role for the PPTN in the control of various rhythmic behaviors, including waking/sleeping and locomotion. Recently, rhythmic activity in the local field potentials was recorded from the PPTN of patients with Parkinson's disease who were treated with levodopa, suggesting that rhythmic firing is a feature of the functioning PPTN and might change with the behaving conditions even within waking. However, it remains unclear whether and how single PPTN neurons exhibit rhythmic firing patterns during various behaving conditions, including executing conditioned eye movement behaviors, seeking reward, or during resting. We previously recorded from PPTN neurons in healthy monkeys during visually guided saccade tasks and reported task-related changes in firing rate, and in this paper, we reanalyzed these data and focused on their firing patterns. A population of PPTN neurons demonstrated a regular firing pattern in that the coefficient of variation of interspike intervals was lower than what would be expected of theoretical random and irregular spike trains. Furthermore, a group of PPTN neurons exhibited a clear periodic single spike firing that changed with the context of the behavioral task. Many of these neurons exhibited a periodic firing pattern during highly active conditions, either the fixation condition during the saccade task or the free-viewing condition during the intertrial interval. We speculate that these task context-related changes in rhythmic firing of PPTN neurons might regulate the monkey's attentional and vigilance state to perform the task.

  9. Aphotic N2 fixation along an oligotrophic to ultraoligotrophic transect in the western tropical South Pacific Ocean

    Science.gov (United States)

    Benavides, Mar; Shoemaker, Katyanne M.; Moisander, Pia H.; Niggemann, Jutta; Dittmar, Thorsten; Duhamel, Solange; Grosso, Olivier; Pujo-Pay, Mireille; Hélias-Nunige, Sandra; Fumenia, Alain; Bonnet, Sophie

    2018-05-01

    The western tropical South Pacific (WTSP) Ocean has been recognized as a global hot spot of dinitrogen (N2) fixation. Here, as in other marine environments across the oceans, N2 fixation studies have focused on the sunlit layer. However, studies have confirmed the importance of aphotic N2 fixation activity, although until now only one had been performed in the WTSP. In order to increase our knowledge of aphotic N2 fixation in the WTSP, we measured N2 fixation rates and identified diazotrophic phylotypes in the mesopelagic layer along a transect spanning from New Caledonia to French Polynesia. Because non-cyanobacterial diazotrophs presumably need external dissolved organic matter (DOM) sources for their nutrition, we also identified DOM compounds using Fourier transform ion cyclotron resonance mass spectrometry (FTICRMS) with the aim of searching for relationships between the composition of DOM and non-cyanobacterial N2 fixation in the aphotic ocean. N2 fixation rates were low (average 0.63 ± 0.07 nmol N L-1 d-1) but consistently detected across all depths and stations, representing ˜ 6-88 % of photic N2 fixation. N2 fixation rates were not significantly correlated with DOM compounds. The analysis of nifH gene amplicons revealed a wide diversity of non-cyanobacterial diazotrophs, mostly matching clusters 1 and 3. Interestingly, a distinct phylotype from the major nifH subcluster 1G dominated at 650 dbar, coinciding with the oxygenated Subantarctic Mode Water (SAMW). This consistent pattern suggests that the distribution of aphotic diazotroph communities is to some extent controlled by water mass structure. While the data available are still too scarce to elucidate the distribution and controls of mesopelagic non-cyanobacterial diazotrophs in the WTSP, their prevalence in the mesopelagic layer and the consistent detection of active N2 fixation activity at all depths sampled during our study suggest that aphotic N2 fixation may contribute significantly to fixed

  10. Eye Movement Correlates of Expertise in Visual Arts.

    Science.gov (United States)

    Francuz, Piotr; Zaniewski, Iwo; Augustynowicz, Paweł; Kopiś, Natalia; Jankowski, Tomasz

    2018-01-01

    versions due to dwell time, first and average fixation duration and number of fixations. The familiarity of paintings turned out to be the factor significantly affects both the aesthetic evaluation of paintings and eye movement.

  11. Eye Movement Correlates of Expertise in Visual Arts

    Directory of Open Access Journals (Sweden)

    Piotr Francuz

    2018-03-01

    their altered versions due to dwell time, first and average fixation duration and number of fixations. The familiarity of paintings turned out to be the factor significantly affects both the aesthetic evaluation of paintings and eye movement.

  12. An Infant Development-inspired Approach to Robot Hand-eye Coordination

    Directory of Open Access Journals (Sweden)

    Fei Chao

    2014-02-01

    Full Text Available This paper presents a novel developmental learning approach for hand-eye coordination in an autonomous robotic system. Robotic hand-eye coordination plays an important role in dealing with real-time environments. Under the approach, infant developmental patterns are introduced to build our robot's learning system. The method works by first constructing a brain-like computational structure to control the robot, and then by using infant behavioural patterns to build a hand-eye coordination learning algorithm. This work is supported by an experimental evaluation, which shows that the control system is implemented simply, and that the learning approach provides fast and incremental learning of behavioural competence.

  13. SyntEyes KTC: higher order statistical eye model for developing keratoconus.

    Science.gov (United States)

    Rozema, Jos J; Rodriguez, Pablo; Ruiz Hidalgo, Irene; Navarro, Rafael; Tassignon, Marie-José; Koppen, Carina

    2017-05-01

    To present and validate a stochastic eye model for developing keratoconus to e.g. improve optical corrective strategies. This could be particularly useful for researchers that do not have access to original keratoconic data. The Scheimpflug tomography, ocular biometry and wavefront of 145 keratoconic right eyes were collected. These data were processed using principal component analysis for parameter reduction, followed by a multivariate Gaussian fit that produces a stochastic model for keratoconus (SyntEyes KTC). The output of this model is filtered to remove the occasional incorrect topography patterns by either an automatic or manual procedure. Finally, the output of this keratoconus model is matched to that of the original model for normal eyes using the non-corneal biometry to obtain a description of keratoconus development. The synthetic data generated by the model were found to be significantly equal to the original data (non-parametric Mann-Whitney equivalence test; 145/154 passed). The variability of the synthetic data, however, was often significantly less than that of the original data, especially for the higher order Zernike terms of corneal elevation (non-parametric Levene test; p eyes with incorrect topographies. Interpolation between matched pairs of normal and keratoconic SyntEyes appears to provide an adequate model for keratoconus progression. The synthetic data provided by the proposed keratoconus model closely resembles actual clinical data and may be used for a range of research applications when (sufficient) real data is not available. © 2017 The Authors Ophthalmic & Physiological Optics © 2017 The College of Optometrists.

  14. Developmental visual perception deficits with no indications of prosopagnosia in a child with abnormal eye movements.

    Science.gov (United States)

    Gilaie-Dotan, Sharon; Doron, Ravid

    2017-06-01

    Visual categories are associated with eccentricity biases in high-order visual cortex: Faces and reading with foveally-biased regions, while common objects and space with mid- and peripherally-biased regions. As face perception and reading are among the most challenging human visual skills, and are often regarded as the peak achievements of a distributed neural network supporting common objects perception, it is unclear why objects, which also rely on foveal vision to be processed, are associated with mid-peripheral rather than with a foveal bias. Here, we studied BN, a 9 y.o. boy who has normal basic-level vision, abnormal (limited) oculomotor pursuit and saccades, and shows developmental object and contour integration deficits but with no indication of prosopagnosia. Although we cannot infer causation from the data presented here, we suggest that normal pursuit and saccades could be critical for the development of contour integration and object perception. While faces and perhaps reading, when fixated upon, take up a small portion of central visual field and require only small eye movements to be properly processed, common objects typically prevail in mid-peripheral visual field and rely on longer-distance voluntary eye movements as saccades to be brought to fixation. While retinal information feeds into early visual cortex in an eccentricity orderly manner, we hypothesize that propagation of non-foveal information to mid and high-order visual cortex critically relies on circuitry involving eye movements. Limited or atypical eye movements, as in the case of BN, may hinder normal information flow to mid-eccentricity biased high-order visual cortex, adversely affecting its development and consequently inducing visual perceptual deficits predominantly for categories associated with these regions. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Eye tracking and climate change: How is climate literacy information processed?

    Science.gov (United States)

    Williams, C. C.; McNeal, K. S.

    2011-12-01

    The population of the Southeastern United States is perceived to be resistant to information regarding global climate change. The Climate Literacy Partnership in the Southeast (CLiPSE) project was formed to provide a resource for climate science information. As part of this project, we are evaluating the way that education materials influence the interpretation of climate change related information. At Mississippi State University, a study is being conducted examining how individuals from the Southeastern United States process climate change information and whether or not the interaction with such information impacts the interpretation of subsequent climate change related information. By observing the patterns both before and after an educational intervention, we are able to evaluate the effectiveness of the climate change information on an individual's interpretation of related information. Participants in this study view figures describing various types of climate change related information (CO2 emissions, sea levels, etc.) while their eye movements are tracked to determine a baseline for the way that they process this type of graphical data. Specifically, we are examining time spent viewing and number of fixations on critical portions of the figures prior to exposure to an educational document on climate change. Following the baseline period, we provide participants with portions of a computerized version of Climate Literacy: The Essential Principles of Climate Sciences that the participants read at their own pace while their eye movements are monitored. Participants are told that they will be given a test on the material after reading the resource. After reading the excerpt, participants are presented with a new set of climate change related figures to interpret (with eye tracking) along with a series of questions regarding information contained in the resource. We plan to evaluate changes that occur in the way that climate change related information is

  16. Preferred retinal locus in macular disease: characteristics and clinical implications.

    Science.gov (United States)

    Greenstein, Vivienne C; Santos, Rodrigo A V; Tsang, Stephen H; Smith, R Theodore; Barile, Gaetano R; Seiple, William

    2008-10-01

    To investigate the location and fixation stability of preferred retinal locations (PRLs) in patients with macular disease, and the relationship among areas of abnormal fundus autofluorescence, the PRL and visual sensitivity. Fifteen patients (15 eyes) were studied. Seven had Stargardt disease, 1 bull's eye maculopathy, 5 age-related macular degeneration, 1 Best disease, and 1 pattern dystrophy. All tested eyes had areas of abnormal fundus autofluorescence. The PRL was evaluated with fundus photography and the Nidek microperimeter. Visual field sensitivity was measured with the Nidek microperimeter. Of the 15 eyes, 4 had foveal and 11 had eccentric fixation. Eccentric PRLs were above the atrophic lesion and their stability did not depend on the degree of eccentricity from the fovea. Visual sensitivity was markedly decreased in locations corresponding to hypofluorescent areas. Sensitivity was not decreased in hyperfluorescent areas corresponding to flecks but was decreased if hyperfluorescence was in the form of dense annuli. Eccentric PRLs were in the superior retina in regions of normal fundus autofluorescence. Fixation stability was not correlated with the degree of eccentricity from the fovea. To assess the outcomes of treatment trials it is important to use methods that relate retinal morphology to visual function.

  17. Object based implicit contextual learning: a study of eye movements.

    Science.gov (United States)

    van Asselen, Marieke; Sampaio, Joana; Pina, Ana; Castelo-Branco, Miguel

    2011-02-01

    Implicit contextual cueing refers to a top-down mechanism in which visual search is facilitated by learned contextual features. In the current study we aimed to investigate the mechanism underlying implicit contextual learning using object information as a contextual cue. Therefore, we measured eye movements during an object-based contextual cueing task. We demonstrated that visual search is facilitated by repeated object information and that this reduction in response times is associated with shorter fixation durations. This indicates that by memorizing associations between objects in our environment we can recognize objects faster, thereby facilitating visual search.

  18. Yarbus, Eye Movements, and Vision

    Directory of Open Access Journals (Sweden)

    Benjamin W Tatler

    2010-04-01

    Full Text Available The impact of Yarbus's research on eye movements was enormous following the translation of his book Eye Movements and Vision into English in 1967. In stark contrast, the published material in English concerning his life is scant. We provide a brief biography of Yarbus and assess his impact on contemporary approaches to research on eye movements. While early interest in his work focused on his study of stabilised retinal images, more recently this has been replaced with interest in his work on the cognitive influences on scanning patterns. We extended his experiment on the effect of instructions on viewing a picture using a portrait of Yarbus rather than a painting. The results obtained broadly supported those found by Yarbus.

  19. Fixation probability on clique-based graphs

    Science.gov (United States)

    Choi, Jeong-Ok; Yu, Unjong

    2018-02-01

    The fixation probability of a mutant in the evolutionary dynamics of Moran process is calculated by the Monte-Carlo method on a few families of clique-based graphs. It is shown that the complete suppression of fixation can be realized with the generalized clique-wheel graph in the limit of small wheel-clique ratio and infinite size. The family of clique-star is an amplifier, and clique-arms graph changes from amplifier to suppressor as the fitness of the mutant increases. We demonstrate that the overall structure of a graph can be more important to determine the fixation probability than the degree or the heat heterogeneity. The dependence of the fixation probability on the position of the first mutant is discussed.

  20. Differences in Looking at Own- and Other-Race Faces Are Subtle and Analysis-Dependent: An Account of Discrepant Reports.

    Science.gov (United States)

    Arizpe, Joseph; Kravitz, Dwight J; Walsh, Vincent; Yovel, Galit; Baker, Chris I

    2016-01-01

    The Other-Race Effect (ORE) is the robust and well-established finding that people are generally poorer at facial recognition of individuals of another race than of their own race. Over the past four decades, much research has focused on the ORE because understanding this phenomenon is expected to elucidate fundamental face processing mechanisms and the influence of experience on such mechanisms. Several recent studies of the ORE in which the eye-movements of participants viewing own- and other-race faces were tracked have, however, reported highly conflicting results regarding the presence or absence of differential patterns of eye-movements to own- versus other-race faces. This discrepancy, of course, leads to conflicting theoretical interpretations of the perceptual basis for the ORE. Here we investigate fixation patterns to own- versus other-race (African and Chinese) faces for Caucasian participants using different analysis methods. While we detect statistically significant, though subtle, differences in fixation pattern using an Area of Interest (AOI) approach, we fail to detect significant differences when applying a spatial density map approach. Though there were no significant differences in the spatial density maps, the qualitative patterns matched the results from the AOI analyses reflecting how, in certain contexts, Area of Interest (AOI) analyses can be more sensitive in detecting the differential fixation patterns than spatial density analyses, due to spatial pooling of data with AOIs. AOI analyses, however, also come with the limitation of requiring a priori specification. These findings provide evidence that the conflicting reports in the prior literature may be at least partially accounted for by the differences in the statistical sensitivity associated with the different analysis methods employed across studies. Overall, our results suggest that detection of differences in eye-movement patterns can be analysis-dependent and rests on the

  1. Graft fixation in cruciate ligament reconstruction.

    Science.gov (United States)

    Brand, J; Weiler, A; Caborn, D N; Brown, C H; Johnson, D L

    2000-01-01

    Cruciate ligament reconstruction has progressed dramatically in the last 20 years. Anatomic placement of ligament substitutes has fostered rehabilitation efforts that stress immediate and full range of motion, immediate weightbearing, neuromuscular strength and coordination, and early return to athletic competition (3 months). This has placed extreme importance on secure graft fixation at the time of ligament reconstruction. Current ligament substitutes require a bony or soft tissue component to be fixed within a bone tunnel or on the periosteum at a distance from the normal ligament attachment site. Fixation devices have progressed from metal to biodegradable and from far to near-normal native ligament attachment sites. Ideally, the biomechanical properties of the entire graft construct would approach those of the native ligament and facilitate biologic incorporation of the graft. Fixation should be done at the normal anatomic attachment site of the native ligament (aperture fixation) and, over time, allow the biologic return of the histologic transition zone from ligament to fibrocartilage, to calcified fibrocartilage, to bone. The purpose of this article is to review current fixation devices and techniques in cruciate ligament surgery.

  2. Intratarsal fixation at the same level as the skin incision to reduce asymmetric double eyelids: evaluation of symmetry using photogrammetry.

    Science.gov (United States)

    Han, Kihwan; Yeo, Hyeonjung; Choi, Tae Hyun; Son, Daegu; Kim, Jun Hyung

    2010-03-01

    One of the most common complications of double eyelid operations is asymmetry. To reduce asymmetry, we fixed the dermis to the tarsal plate at the same level as the skin incision, and objectively evaluated the symmetry of the height using photogrammetry.Of 30 patients who had double eyelid operations by the intratarsal fixation technique, 15 patients completed a minimum follow-up of 6 months. After the skin incision and removal of the orbicularis oculi muscle and the orbital fat, the pretarsal fat pad was excised to expose the superior portion of the tarsal plate. The 3 fixation points were marked on the tarsal plate at the same level with the skin incision using a spreading caliper. The dermis was fixed to the marked points of the tarsal plate and the skin was closed.The height of the double eyelid was measured by clinical photography at 4 points when the eyes were opened and at 3 points when the eyes were closed. The height proportional index at each point was obtained by dividing the height of the left double eyelid by that of the right double eyelid. We compared each height proportional index with "1" to evaluate the symmetry of both double eyelids using a paired t test.The follow-up period was an average of 9.0 months. The mean height proportional indices were 0.97 (a), 0.96 (b), 0.98 (c), 1.08 (d), 0.97 (e), 1.02 (f), and 1.13 (g). According to a paired t test, the height of the left double eyelid was not different from that of the right double eyelid.Intratarsal fixation, along with other previously known methods, decreases asymmetric double eyelids.

  3. External fixation of "intertrochanteric" fractures.

    Science.gov (United States)

    Gani, Naseem Ul; Kangoo, Khursheed Ahmed; Bashir, Arshad; Muzaffer, Rahil; Bhat, Mohammad Farooq; Farooq, Munir; Badoo, Abdul Rashid; Dar, Imtiyaz Hussian; Wani, Mudassir Maqbool

    2009-10-10

    In developing countries, due to limited availability of modern anesthesia and overcrowding of the hospitals with patients who need surgery, high-risk patients with "intertrochanteric" fractures remain unsuita ble for open reduction and internal fixation.The aim of this study was to analyze the results of external fixation of "intertrochanteric" fractures in high-risk geriatric patients in a developing country.The results of 62 ambulatory high-risk geriatric patients with a mean age of 70 years (range 58-90 years) with "intertrochanteric" fractures, in whom external fixation was performed, are reported.Eight patients died during follow-up due to medical causes unrelated to the surgical procedure. So only 54 patients were available for final assessment. Procedure is simple, performed under local anesthesia, requires less time for surgery and is associated with less blood loss. Good fixation and early ambulation was achieved in most of the patients. Average time to union was 14 weeks. Thirty-one patients developed superficial pin tract infection and 28 patients had average shortening of 15 mm due to impaction and varus angulation. Functional outcome was assessed using Judet's point system. Good to excellent results were achieved in 44 patients.This study demonstrated that external fixation of "intertrochantric" fractures performed under local anesthesia offers significant advantage in ambulatory high-risk geriatric patients especially in a developing country.

  4. Robust biological nitrogen fixation in a model grass-bacterial association.

    Science.gov (United States)

    Pankievicz, Vânia C S; do Amaral, Fernanda P; Santos, Karina F D N; Agtuca, Beverly; Xu, Youwen; Schueller, Michael J; Arisi, Ana Carolina M; Steffens, Maria B R; de Souza, Emanuel M; Pedrosa, Fábio O; Stacey, Gary; Ferrieri, Richard A

    2015-03-01

    Nitrogen-fixing rhizobacteria can promote plant growth; however, it is controversial whether biological nitrogen fixation (BNF) from associative interaction contributes to growth promotion. The roots of Setaria viridis, a model C4 grass, were effectively colonized by bacterial inoculants resulting in a significant enhancement of growth. Nitrogen-13 tracer studies provided direct evidence for tracer uptake by the host plant and incorporation into protein. Indeed, plants showed robust growth under nitrogen-limiting conditions when inoculated with an ammonium-excreting strain of Azospirillum brasilense. (11)C-labeling experiments showed that patterns in central carbon metabolism and resource allocation exhibited by nitrogen-starved plants were largely reversed by bacterial inoculation, such that they resembled plants grown under nitrogen-sufficient conditions. Adoption of S. viridis as a model should promote research into the mechanisms of associative nitrogen fixation with the ultimate goal of greater adoption of BNF for sustainable crop production. © 2015 The Authors The Plant Journal © 2015 John Wiley & Sons Ltd.

  5. Phase-Contrast Hounsfield Units of Fixated and Non-Fixated Soft-Tissue Samples

    Science.gov (United States)

    Willner, Marian; Fior, Gabriel; Marschner, Mathias; Birnbacher, Lorenz; Schock, Jonathan; Braun, Christian; Fingerle, Alexander A.; Noël, Peter B.; Rummeny, Ernst J.; Pfeiffer, Franz; Herzen, Julia

    2015-01-01

    X-ray phase-contrast imaging is a novel technology that achieves high soft-tissue contrast. Although its clinical impact is still under investigation, the technique may potentially improve clinical diagnostics. In conventional attenuation-based X-ray computed tomography, radiological diagnostics are quantified by Hounsfield units. Corresponding Hounsfield units for phase-contrast imaging have been recently introduced, enabling a setup-independent comparison and standardized interpretation of imaging results. Thus far, the experimental values of few tissue types have been reported; these values have been determined from fixated tissue samples. This study presents phase-contrast Hounsfield units for various types of non-fixated human soft tissues. A large variety of tissue specimens ranging from adipose, muscle and connective tissues to liver, kidney and pancreas tissues were imaged by a grating interferometer with a rotating-anode X-ray tube and a photon-counting detector. Furthermore, we investigated the effects of formalin fixation on the quantitative phase-contrast imaging results. PMID:26322638

  6. Model simulation studies to clarify the effect on saccadic eye movements of initial condition velocities set by the Vestibular Ocular Reflex (VOR)

    Science.gov (United States)

    Nam, M. H.; Winters, J. M.; Stark, L.

    1981-01-01

    Voluntary active head rotations produced vestibulo-ocular reflex eye movements (VOR) with the subject viewing a fixation target. When this target jumped, the size of the refixation saccades were a function of the ongoing initial velocity of the eye. Saccades made against the VOR were larger in magnitude. Simulation of a reciprocally innervated model eye movement provided results comparable to the experimental data. Most of the experimental effect appeared to be due to linear summation for saccades of 5 and 10 degree magnitude. For small saccades of 2.5 degrees, peripheral nonlinear interaction of state variables in the neuromuscular plant also played a role as proven by comparable behavior in the simulated model with known controller signals.

  7. Evidence for a functional subdivision of Premotor Ear-Eye Field (Area 8B.

    Directory of Open Access Journals (Sweden)

    Marco eLanzilotto

    2015-01-01

    Full Text Available The Supplementary Eye Field (SEF and the Frontal Eye Field (FEF have been described as participating in gaze shift control. Recent evidence suggests, however, that other areas of the dorsomedial prefrontal cortex also influence gaze shift. Herein, we have investigated electrically evoked ear- and eye movements from the Premotor Ear-Eye Field, or PEEF (area 8B of macaque monkeys. We stimulated PEEF during spontaneous condition (outside the task performance and during the execution of a visual fixation task (VFT. In the first case, we functionally identified two regions within the PEEF: a core and a belt. In the core region, stimulation elicited forward ear movements; regarding the evoked eye movements, in some penetrations, stimulation elicited contraversive fixed-vectors with a mean amplitude of 5.14°; while in other penetrations, we observed prevalently contralateral goal-directed eye movements having end-points that fell within 15° in respect to the primary eye position. On the contrary, in the belt region, stimulation elicited backward ear movements; regarding the eye movements, in some penetrations stimulation elicited prevalently contralateral goal-directed eye movements having end-points that fell within 15° in respect to the primary eye position, while in the lateral edge of the investigated region, stimulation elicited contralateral goal-directed eye movements having end-points that fell beyond 15° in respect to the primary eye position. Stimulation during VFT either did not elicit eye movements or evoked saccades of only a few degrees. Finally, even though no head rotation movements were observed during the stimulation period, we viewed a relationship between the duration of stimulation and the neck forces exerted by the monkey’s head. We propose an updated vision of the PEEF composed of two functional regions, core and belt, which may be involved in integrating auditory and visual information important to the programming of gaze

  8. Seeing to hear? Patterns of gaze to speaking faces in children with autism spectrum disorders.

    Directory of Open Access Journals (Sweden)

    Julia eIrwin

    2014-05-01

    Full Text Available Using eye-tracking methodology, gaze to a speaking face was compared in a group of children with autism spectrum disorders (ASD and those with typical development (TD. Patterns of gaze were observed under three conditions: audiovisual (AV speech in auditory noise, visual only speech and an AV non-face, non-speech control. Children with ASD looked less to the face of the speaker and fixated less on the speakers’ mouth than TD controls. No differences in gaze were reported for the non-face, non-speech control task. Since the mouth holds much of the articulatory information available on the face, these findings suggest that children with ASD may have reduced access to critical linguistic information. This reduced access to visible articulatory information could be a contributor to the communication and language problems exhibited by children with ASD.

  9. Methanotrophy induces nitrogen fixation during peatland development

    Science.gov (United States)

    Larmola, Tuula; Leppänen, Sanna M.; Tuittila, Eeva-Stiina; Aarva, Maija; Merilä, Päivi; Fritze, Hannu; Tiirola, Marja

    2014-01-01

    Nitrogen (N) accumulation rates in peatland ecosystems indicate significant biological atmospheric N2 fixation associated with Sphagnum mosses. Here, we show that the linkage between methanotrophic carbon cycling and N2 fixation may constitute an important mechanism in the rapid accumulation of N during the primary succession of peatlands. In our experimental stable isotope enrichment study, previously overlooked methane-induced N2 fixation explained more than one-third of the new N input in the younger peatland stages, where the highest N2 fixation rates and highest methane oxidation activities co-occurred in the water-submerged moss vegetation. PMID:24379382

  10. Polymeric media for tritium fixation. Supplement I

    International Nuclear Information System (INIS)

    Franz, J.A.; Burger, L.L.

    1976-01-01

    Procedures for the fixation of tritium as TH or THO in two different polymeric media are described. The complete procedure for THO fixation in a polyureylene-polyurethane polumer, including polymer molding procedures and leach tests is presented. The catalytic tritiation of polystyrene under very mild conditions using a rhodium catalyst is also described. Thermal stabilities and cost estimates for the polymers examined under this program are discussed. Organic polymers were found to have attractive features for the fixation and storage of concentrated tritium wastes due to the convenience of fixation procedures and favorable properties of the resulting media

  11. Fixation of Selenium by Clay Minerals and Iron Oxides

    DEFF Research Database (Denmark)

    Hamdy, A. A.; Nielsen, Gunnar Gissel

    1977-01-01

    In studying Se fixation, soil components capable of retaining Se were investigated. The importance of Fe hydrous oxides in the fixation of Se was established. The clay minerals common to soils, such as kaolinite, montmorillonite and vermiculite, all exhibited Se fixation, but greater fixation occ...

  12. A novel evaluation of two related and two independent algorithms for eye movement classification during reading.

    Science.gov (United States)

    Friedman, Lee; Rigas, Ioannis; Abdulin, Evgeny; Komogortsev, Oleg V

    2018-05-15

    Nystrӧm and Holmqvist have published a method for the classification of eye movements during reading (ONH) (Nyström & Holmqvist, 2010). When we applied this algorithm to our data, the results were not satisfactory, so we modified the algorithm (now the MNH) to better classify our data. The changes included: (1) reducing the amount of signal filtering, (2) excluding a new type of noise, (3) removing several adaptive thresholds and replacing them with fixed thresholds, (4) changing the way that the start and end of each saccade was determined, (5) employing a new algorithm for detecting PSOs, and (6) allowing a fixation period to either begin or end with noise. A new method for the evaluation of classification algorithms is presented. It was designed to provide comprehensive feedback to an algorithm developer, in a time-efficient manner, about the types and numbers of classification errors that an algorithm produces. This evaluation was conducted by three expert raters independently, across 20 randomly chosen recordings, each classified by both algorithms. The MNH made many fewer errors in determining when saccades start and end, and it also detected some fixations and saccades that the ONH did not. The MNH fails to detect very small saccades. We also evaluated two additional algorithms: the EyeLink Parser and a more current, machine-learning-based algorithm. The EyeLink Parser tended to find more saccades that ended too early than did the other methods, and we found numerous problems with the output of the machine-learning-based algorithm.

  13. Pathway of /sup 14/Co/sub 2/ fixation in marine algae

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, G V; Karekar, M D [Shivaji Univ., Kolhapur (India). Dept. of Botany

    1973-08-01

    Marine plants have a different metabolic environment which is likely to affect pathways of CO/sub 2/ fixation. It has been observed that in marine alga, Ulva lactuca, during short term light fixation of /sup 14/CO/sub 2/, besides PGA, an appreciable amount of activity was located in aspartate. This curious observation can now be explained on the basis of Hatch, Slack and Kortschak pathway of CO/sub 2/ fixation. In order to trace pathways of /sup 14/CO/sub 2/ in marine algae, a wide variety of algal specimens were exposed to NaH/sup 14/CO/sub 3/ in light and the products were analyzed. The algae selected were Ulva lactuca, Sargassum ilicifolium, Sphacelaria sp., Padina tetrastromatica, Chaetomorpha media and Enteromorpha tubulosa. It has been found that the pathways of CO/sub 2/ in the above marine algae differ from the conventional pattern recorded in Chlorella. The early labelling of aspartate and its subsequent utilization indicates that HSK pathway is operative in the marine algae. Malate synthesis is inhibited due to the effect of saline environment on the activity of malic dehydrogenase. Appreciable label in PGA is suggestive of the fact that Calvin and Bassham pathway as well as the HSK route are simultaneously operating. (auth)

  14. The perceptual cognitive processes underpinning skilled performance in volleyball: evidence from eye-movements and verbal reports of thinking involving an in situ representative task.

    Science.gov (United States)

    Afonso, José; Garganta, Jêlio; McRobert, Allistair; Williams, Andrew M; Mesquita, Isabel

    2012-01-01

    An extensive body of work has focused on the processes underpinning perceptual-cognitive expertise. The majority of researchers have used film-based simulations to capture superior performance. We combined eye movement recording and verbal reports of thinking to explore the processes underpinning skilled performance in a complex, dynamic, and externally paced representative volleyball task involving in situ data collection. Altogether, 27 female volleyball players performed as centre backcourt defenders in simulated sessions while wearing an eye-tracking device. After each sequence, athletes were questioned concerning their perception of the situation. The visual search strategies employed by the highly-skilled players were more exploratory than those used by skilled players, involving more fixations to a greater number of locations. Highly-skilled participants spent more time fixating on functional spaces between two or more display areas, while the skilled participants fixated on the ball trajectory and specific players. Moreover, highly-skilled players generated more condition concepts with higher levels of sophistication than their skilled counterparts. Findings highlight the value of using representative task designs to capture performance in situ. Key pointsDecision-making in complex sports relies deeply on perceptual-cognitive expertise. In turn, the effect of expertise is highly dependent on the nature and complexity of the task.Nonetheless, most researchers use simple tasks in their research designs, risking not capturing performance in a meaningful way. We proposed to use a live action setting with a complex task design, representative of real world situations.We combined eye movement registration with collection of immediate retrospective verbal reports. Although the two data sets are not directly comparable, they may be used in a complementary manner, providing a deeper and fuller understanding of the processes underpinning superior performance

  15. Evaluation of functional outcome of pilon fractures managed with limited internal fixation and external fixation: A prospective clinical study.

    Science.gov (United States)

    Meena, Umesh Kumar; Bansal, Mahesh Chand; Behera, Prateek; Upadhyay, Rahul; Gothwal, Gyan Chand

    2017-11-01

    The management of pilon fractures is controversial primarily due to the high rate of complications irrespective of the mode of treatment. Limited internal fixation with external fixation is associated with minimal soft tissue handling. This may reduce the chances of wound dehiscence and infection. This study was designed to evaluate the functional and clinical outcomes in patients treated with limited internal fixation combined with external fixation in pilon fractures. This study was conducted as a prospective clinical study on 56 skeletally mature patients with closed fractures with poor skin condition, and with open grade 1 and grade 2 distal tibial intra-articular fractures. All patients were treated with combined limited internal fixation and ankle spanning external fixation. All fractures in this series united with an average time period of union of 18.3weeks (ranging from 13 weeks to 30 weeks). There was no non-union in any case. There was malunion in 4 cases, varus malunion (>5 degree) in 2 cases and recurvatum in another 2 cases). Excellent to good functional results were observed in 88% cases based on the modified Ovadia and Beals score. The mean ankle dorsiflexion and planter flexion movements were 10.2±5.3 degrees and 27.4±7.2 degrees respectively. infections occurred in 6 patients which included 4 pin tract infections and 2 superficial wound infection, all 6 healed after removal of pin tract and with oral antibiotics. The technique of combined external fixation with internal fixation is safe and effective management option for intra-articular distal tibial fractures.

  16. A new surgical technique of intra-scleral tube fixation in Ahmed Glaucoma Valve implantation: ‘Scleral Sleeve Method’

    Directory of Open Access Journals (Sweden)

    Charudutt Kalamkar

    2017-10-01

    Full Text Available Purpose: To present a new surgical technique ‘Scleral Sleeve Method’ which would reduce the risk of Ahmed Glaucoma Valve (AGV tube related complications in patients undergoing AGV FP7 (New World Medical Inc., Rancho Cucamonga, CA for refractory glaucoma. Design: Prospective, Non-Randomized, hospital based interventional case series. Subjects: A total of 16 eyes of adult patients (10 males and 6 females with refractory glaucoma. Methods: Instead of using sutures to fix the AGV tube to sclera, we devised a novel method of intra-scleral tube fixation by creating a scleral tunnel fashioned in form of sleeve. Main outcome measure: Post-operative tube related complications. Result: There were no tube related complications such as exposure, extrusion or retraction in any of the cases. Conclusion: Use of scleral sleeve method for tube fixation, along with graft to cover the tube, will provide additional safety measure and reduce the risks of tube related complications. Keywords: Ahmed Glaucoma Valve, Scleral Sleeve Method, Intra-scleral tube fixation

  17. Towards Diagram Understanding: A Pilot Study Measuring Cognitive Workload Through Eye-Tracking

    DEFF Research Database (Denmark)

    Maier, Anja; Baltsen, Nick; Christoffersen, Henrik

    2014-01-01

    We investigate model understanding, in particular , how the quality of the UML diagram layout impacts cognitive load. We hypothesize that this w ill have a significant impact on the structure and effectiveness of engineers’ communication. In previous work, we have studied task performance...... measurements and subjective assessments; here, we also investigate behavioral indicators such as fixation and pupillary dilation. We use such indicators to explore diagram understanding- and reading strategies and how such strategies are impacted, e.g. by diagram type and expertise level. In the pilot eye...

  18. Tracking without perceiving: a dissociation between eye movements and motion perception.

    Science.gov (United States)

    Spering, Miriam; Pomplun, Marc; Carrasco, Marisa

    2011-02-01

    Can people react to objects in their visual field that they do not consciously perceive? We investigated how visual perception and motor action respond to moving objects whose visibility is reduced, and we found a dissociation between motion processing for perception and for action. We compared motion perception and eye movements evoked by two orthogonally drifting gratings, each presented separately to a different eye. The strength of each monocular grating was manipulated by inducing adaptation to one grating prior to the presentation of both gratings. Reflexive eye movements tracked the vector average of both gratings (pattern motion) even though perceptual responses followed one motion direction exclusively (component motion). Observers almost never perceived pattern motion. This dissociation implies the existence of visual-motion signals that guide eye movements in the absence of a corresponding conscious percept.

  19. Pattern-reversal electroretinograms in unilateral glaucoma.

    Science.gov (United States)

    Wanger, P; Persson, H E

    1983-06-01

    Pattern-reversal and flash electroretinograms (ERG) and oscillatory potentials (OP) were recorded from 11 patients with unilateral glaucoma. All glaucomatous eyes had reduced amplitudes both compared to the opposite eye in the same patient and to reference values. In 10 of the 11 cases this reduction was below the level of normal variation. The difference in pattern-reversal ERG amplitude means from glaucomatous and opposite eyes was statistically significant. No differences were observed in flash ERGs or OPs. The histopathologic correlate to the visual field defects in glaucoma is retinal ganglion cell degeneration. The present electrophysiologic findings support the view, based on results from animal experiments, that the pattern-reversal ERG reflects ganglion cell activity.

  20. Fixation Time for Evolutionary Graphs

    Science.gov (United States)

    Nie, Pu-Yan; Zhang, Pei-Ai

    Evolutionary graph theory (EGT) is recently proposed by Lieberman et al. in 2005. EGT is successful for explaining biological evolution and some social phenomena. It is extremely important to consider the time of fixation for EGT in many practical problems, including evolutionary theory and the evolution of cooperation. This study characterizes the time to asymptotically reach fixation.