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Sample records for extremely small size

  1. Small body size and extreme cortical bone remodeling indicate phyletic dwarfism in Magyarosaurus dacus (Sauropoda: Titanosauria).

    Science.gov (United States)

    Stein, Koen; Csiki, Zoltan; Rogers, Kristina Curry; Weishampel, David B; Redelstorff, Ragna; Carballido, Jose L; Sander, P Martin

    2010-05-18

    Sauropods were the largest terrestrial tetrapods (>10(5) kg) in Earth's history and grew at rates that rival those of extant mammals. Magyarosaurus dacus, a titanosaurian sauropod from the Upper Cretaceous (Maastrichtian) of Romania, is known exclusively from small individuals (dwarfism (phyletic nanism) in dinosaurs, but a recent study suggested that the small Romanian titanosaurs actually represent juveniles of a larger-bodied taxon. Here we present strong histological evidence that M. dacus was indeed a dwarf (phyletic nanoid). Bone histological analysis of an ontogenetic series of Magyarosaurus limb bones indicates that even the smallest Magyarosaurus specimens exhibit a bone microstructure identical to fully mature or old individuals of other sauropod taxa. Comparison of histologies with large-bodied sauropods suggests that Magyarosaurus had an extremely reduced growth rate, but had retained high basal metabolic rates typical for sauropods. The uniquely decreased growth rate and diminutive body size in Magyarosaurus were adaptations to life on a Cretaceous island and show that sauropod dinosaurs were not exempt from general ecological principles limiting body size.

  2. Excessive portal flow causes graft failure in extremely small-for-size liver transplantation in pigs

    Institute of Scientific and Technical Information of China (English)

    Hong-Sheng Wang; Tomohiro Narita; Hideyuki Yamaya; Atsushi Nakamura; Satoshi Sekiguchi; Naoki Kawagishi; Akira Sato; Susumu Satomi; Nobuhiro Ohkohchi; Yoshitaka Enomoto; Masahiro Usuda; Shigehito Miyagi; Takeshi Asakura; Hiroo Masuoka; Takashi Aiso; Keisuke Fukushima

    2005-01-01

    AIM: To evaluate the effects of a portocaval shunt on the decrease of excessive portal flow for the prevention of sinusoidal microcirculatory injury in extremely smallfor-size liver transplantation in pigs.METHODS: The right lateral lobe of pigs, i.e. the 25%of the liver, was transplanted orthotopically. The pigs were divided into two groups: graft without portocaval shunt (n = 11) and graft with portocaval shunt (n=11).Survival rate, portal flow, hepatic arterial flow, and histological findings were investigated.RESULTS: In the group without portocaval shunt, all pigs except one died of liver dysfunction within 24 h after transplantation. In the group with portocaval shunt,eight pigs survived for more than 4 d. The portal flow volumes before and after transplantation in the group without portocaval shunt were 118.2±26.9 mL/min/100 g liver tissue and 270.5±72.9 mL/min/100 g liver tissue,respectively. On the other hand, in the group with portocaval shunt, those volumes were 124.2±27.8 mL/min/100 g liver tissue and 42.7±32.3 mL/min/100 g liver tissue, respectively (P<0.01). As for histological findings in the group without portocaval shunt, destruction of the sinusoidal lining and bleeding in the peri-portal areas were observed after reperfusion, but these findings were not recognized in the group with portocaval shunt.CONCLUSION: These results suggest that excessive portal flow is attributed to post transplant liver dysfunction after extreme small-for-size liver transplantation caused by sinusoidal microcirculatory injury.

  3. Small population size and extremely low levels of genetic diversity in island populations of the platypus, Ornithorhynchus anatinus.

    Science.gov (United States)

    Furlan, Elise; Stoklosa, J; Griffiths, J; Gust, N; Ellis, R; Huggins, R M; Weeks, A R

    2012-04-01

    Genetic diversity generally underpins population resilience and persistence. Reductions in population size and absence of gene flow can lead to reductions in genetic diversity, reproductive fitness, and a limited ability to adapt to environmental change increasing the risk of extinction. Island populations are typically small and isolated, and as a result, inbreeding and reduced genetic diversity elevate their extinction risk. Two island populations of the platypus, Ornithorhynchus anatinus, exist; a naturally occurring population on King Island in Bass Strait and a recently introduced population on Kangaroo Island off the coast of South Australia. Here we assessed the genetic diversity within these two island populations and contrasted these patterns with genetic diversity estimates in areas from which the populations are likely to have been founded. On Kangaroo Island, we also modeled live capture data to determine estimates of population size. Levels of genetic diversity in King Island platypuses are perilously low, with eight of 13 microsatellite loci fixed, likely reflecting their small population size and prolonged isolation. Estimates of heterozygosity detected by microsatellites (H(E)= 0.032) are among the lowest level of genetic diversity recorded by this method in a naturally outbreeding vertebrate population. In contrast, estimates of genetic diversity on Kangaroo Island are somewhat higher. However, estimates of small population size and the limited founders combined with genetic isolation are likely to lead to further losses of genetic diversity through time for the Kangaroo Island platypus population. Implications for the future of these and similarly isolated or genetically depauperate populations are discussed.

  4. X-Ray and Extreme Ultraviolet Emission from Small-Sized Kr Clusters Irradiated by 150-fs Laser Pulses

    Institute of Scientific and Technical Information of China (English)

    王骐; 程元丽; 赵永蓬; 夏元钦; 陈建新; 肖亦凡

    2003-01-01

    x-ray and extreme ultraviolet (EUV) emission from Kr clusters irradiated by 150-fs laser pulses at the peak laser intensity of 5×1015W/cm2 was experimentally investigated. Strong transitions (10nm-13nm) from Kr X and Kr 1X were observed and some spectral lines from Kr ⅩⅢ and Kr ⅩⅣ, which have been predicted to be not produced by optical-field-ionization at the laser intensity used, also appeared. The laser energy absorption and the intensity of x-ray emission started to grow remarkably above the backing pressure of 0.5 MPa and to decrease at the backing pressure of 3 MPa. It is suggested that an optimum backing pressure may exist for Kr clusters heated by 150 fs laser pulses at a certain laser intensity to produce x-ray emission.

  5. Extremal sizes of subspace partitions

    CERN Document Server

    Heden, Olof; Nastase, Esmeralda; Sissokho, Papa

    2011-01-01

    A subspace partition $\\Pi$ of $V=V(n,q)$ is a collection of subspaces of $V$ such that each 1-dimensional subspace of $V$ is in exactly one subspace of $\\Pi$. The size of $\\Pi$ is the number of its subspaces. Let $\\sigma_q(n,t)$ denote the minimum size of a subspace partition of $V$ in which the largest subspace has dimension $t$, and let $\\rho_q(n,t)$ denote the maximum size of a subspace partition of $V$ in which the smallest subspace has dimension $t$. In this paper, we determine the values of $\\sigma_q(n,t)$ and $\\rho_q(n,t)$ for all positive integers $n$ and $t$. Furthermore, we prove that if $n\\geq 2t$, then the minimum size of a maximal partial $t$-spread in $V(n+t-1,q)$ is $\\sigma_q(n,t)$.

  6. Small Business Size Standards

    Data.gov (United States)

    Small Business Administration — Certain government programs, such as SBA loan programs and contracting opportunities, are reserved for small business concerns. In order to qualify, businesses must...

  7. Small size sampling

    Directory of Open Access Journals (Sweden)

    Rakesh R. Pathak

    2012-02-01

    Full Text Available Based on the law of large numbers which is derived from probability theory, we tend to increase the sample size to the maximum. Central limit theorem is another inference from the same probability theory which approves largest possible number as sample size for better validity of measuring central tendencies like mean and median. Sometimes increase in sample-size turns only into negligible betterment or there is no increase at all in statistical relevance due to strong dependence or systematic error. If we can afford a little larger sample, statistically power of 0.90 being taken as acceptable with medium Cohen's d (<0.5 and for that we can take a sample size of 175 very safely and considering problem of attrition 200 samples would suffice. [Int J Basic Clin Pharmacol 2012; 1(1.000: 43-44

  8. Extremely Small Sizes for Faint z ˜ 2-8 Galaxies in the Hubble Frontier Fields: A Key Input for Establishing Their Volume Density and UV Emissivity

    Science.gov (United States)

    Bouwens, R. J.; Illingworth, G. D.; Oesch, P. A.; Atek, H.; Lam, D.; Stefanon, M.

    2017-07-01

    We provide the first observational constraints on the sizes of the faintest galaxies lensed by the Hubble Frontier Fields (HFF) clusters. Ionizing radiation from faint galaxies likely drives cosmic reionization, and the HFF initiative provides a key opportunity to find such galaxies. However, we cannot assess their ionizing emissivity without a robust measurement of their sizes, since this is key to quantifying both their prevalence and the faint-end slope to the UV luminosity function. Here we provide the first size constraints with two new techniques. The first utilizes the fact that the detectability of highly magnified galaxies as a function of shear is very dependent on a galaxy’s size. Only the most compact galaxies remain detectable in high-shear regions (versus a larger detectable size range for low shear), a phenomenon we quantify using simulations. Remarkably, however, no correlation is found between the surface density of faint galaxies and the predicted shear, using 87 high-magnification (μ =10-100) z˜ 2-8 galaxies seen behind the first four HFF clusters. This can only be the case if faint (˜ -15 mag) galaxies have significantly smaller sizes than more luminous galaxies, i.e., ≲ 30 mas or 160-240 pc. As a second size probe, we rotate and stack 26 faint high-magnification sources along the major shear axis. Less elongation is found even for objects with an intrinsic half-light radius of 10 mas. Together, these results indicate that extremely faint z˜ 2-8 galaxies have near point-source profiles (half-light radii <30 mas and perhaps 5-10 mas). These results suggest smaller completeness corrections and hence shallower faint-end slopes for the z˜ 2-8 LFs than derived in some recent studies (by {{Δ }}α ≳ 0.1-0.3).

  9. Evaluation of extremely small horizontal emittance

    Directory of Open Access Journals (Sweden)

    T. Okugi

    1999-02-01

    Full Text Available The KEK Accelerator Test Facility (KEK-ATF was constructed to develop technologies for producing a low-emittance beam which will be required by future linear colliders. The KEK-ATF consists of an injector linac, a damping ring, and a beam extraction line. The basic optical structure of the damping ring is a FOBO lattice, which reduces the horizontal dispersion at the center of the bending magnets and, as a consequence, can produce an extremely small emittance beam. To verify the performance of such a unique, low-emittance lattice, it is crucial to measure the horizontal emittance. The horizontal emittance was measured using wire scanners in the beam extraction line. Since the horizontal beam position was not stable, we established a method to correct the measured beam size for position fluctuation (“jitter” and we succeeded in the observation of the so far smallest horizontal emittance in any accelerator. The measured horizontal emittance was 1.37±0.03nm at a beam energy of 1.285 GeV and a bunch population of \\(3–5\\×10^{9}, in agreement with the design value of 1.27–1.34 nm at the beam energy and the bunch population.

  10. Extremely Small Sizes for Faint z~2-8 Galaxies in the Hubble Frontier Fields: A Key Input For Establishing their Volume Density and UV Emissivity

    CERN Document Server

    Bouwens, R J; Oesch, P A; Atek, H; Lam, D; Stefanon, M

    2016-01-01

    We provide the first observational constraints on the sizes of the faintest galaxies lensed by the Hubble Frontier Fields (HFF) clusters. Ionizing radiation from faint galaxies likely drives cosmic reionization, and the HFF initiative provides a key opportunity to find such galaxies. Yet, we cannot really assess their ionizing emissivity without a robust measurement of their sizes, since this is key to quantifying both their prevalence and the faint-end slope to the UV luminosity function. Here we provide the first such size constraints with 2 new techniques. The first utilizes the fact that the detectability of highly-magnified galaxies as a function of shear is very dependent on a galaxy's size. Only the most compact galaxies will remain detectable in regions of high shear (vs. a larger detectable size range for low shear), a phenomenon we carefully quantify using simulations. Remarkably, however, no correlation is found between the surface density of faint galaxies and the predicted shear, using 87 faint h...

  11. SIZE AND SHAPE FACTOR EXTREMES OF SPHEROIDS

    Directory of Open Access Journals (Sweden)

    Daniel Hlubinka

    2011-05-01

    Full Text Available In the paper we consider random prolate (oblate spheroids and their random profiles. The limiting distribution of the extremal characteristics of the spheroids is related to the limiting distribution of the corresponding extremal characteristics of the profiles. The difference between the analysis of the prolate and oblate spheroids is discussed. We propose the possible application of the theoretical results.

  12. Evolution of extreme body size disparity in monitor lizards (Varanus).

    Science.gov (United States)

    Collar, David C; Schulte, James A; Losos, Jonathan B

    2011-09-01

    Many features of species' biology, including life history, physiology, morphology, and ecology are tightly linked to body size. Investigation into the causes of size divergence is therefore critical to understanding the factors shaping phenotypic diversity within clades. In this study, we examined size evolution in monitor lizards (Varanus), a clade that includes the largest extant lizard species, the Komodo dragon (V. komodoensis), as well as diminutive species that are nearly four orders of magnitude smaller in adult body mass. We demonstrate that the remarkable body size disparity of this clade is a consequence of different selective demands imposed by three major habitat use patterns-arboreality, terrestriality, and rock-dwelling. We reconstructed phylogenetic relationships and ancestral habitat use and applied model selection to determine that the best-fitting evolutionary models for species' adult size are those that infer oppositely directed adaptive evolution associated with terrestriality and rock-dwelling, with terrestrial lineages evolving extremely large size and rock-dwellers becoming very small. We also show that habitat use affects the evolution of several ecologically important morphological traits independently of body size divergence. These results suggest that habitat use exerts a strong, multidimensional influence on the evolution of morphological size and shape disparity in monitor lizards.

  13. Introducing the refined gravity hypothesis of extreme sexual size dimorphism

    Directory of Open Access Journals (Sweden)

    Corcobado Guadalupe

    2010-08-01

    Full Text Available Abstract Background Explanations for the evolution of female-biased, extreme Sexual Size Dimorphism (SSD, which has puzzled researchers since Darwin, are still controversial. Here we propose an extension of the Gravity Hypothesis (i.e., the GH, which postulates a climbing advantage for small males that in conjunction with the fecundity hypothesis appears to have the most general power to explain the evolution of SSD in spiders so far. In this "Bridging GH" we propose that bridging locomotion (i.e., walking upside-down under own-made silk bridges may be behind the evolution of extreme SSD. A biomechanical model shows that there is a physical constraint for large spiders to bridge. This should lead to a trade-off between other traits and dispersal in which bridging would favor smaller sizes and other selective forces (e.g. fecundity selection in females would favor larger sizes. If bridging allows faster dispersal, small males would have a selective advantage by enjoying more mating opportunities. We predicted that both large males and females would show a lower propensity to bridge, and that SSD would be negatively correlated with sexual dimorphism in bridging propensity. To test these hypotheses we experimentally induced bridging in males and females of 13 species of spiders belonging to the two clades in which bridging locomotion has evolved independently and in which most of the cases of extreme SSD in spiders are found. Results We found that 1 as the degree of SSD increased and females became larger, females tended to bridge less relative to males, and that 2 smaller males and females show a higher propensity to bridge. Conclusions Physical constraints make bridging inefficient for large spiders. Thus, in species where bridging is a very common mode of locomotion, small males, by being more efficient at bridging, will be competitively superior and enjoy more mating opportunities. This "Bridging GH" helps to solve the controversial question of

  14. The Estimation of Probability of Extreme Events for Small Samples

    Science.gov (United States)

    Pisarenko, V. F.; Rodkin, M. V.

    2017-02-01

    The most general approach to the study of rare extreme events is based on the extreme value theory. The fundamental General Extreme Value Distribution lies in the basis of this theory serving as the limit distribution for normalized maxima. It depends on three parameters. Usually the method of maximum likelihood (ML) is used for the estimation that possesses well-known optimal asymptotic properties. However, this method works efficiently only when sample size is large enough ( 200-500), whereas in many applications the sample size does not exceed 50-100. For such sizes, the advantage of the ML method in efficiency is not guaranteed. We have found that for this situation the method of statistical moments (SM) works more efficiently over other methods. The details of the estimation for small samples are studied. The SM is applied to the study of extreme earthquakes in three large virtual seismic zones, representing the regime of seismicity in subduction zones, intracontinental regime of seismicity, and the regime in mid-ocean ridge zones. The 68%-confidence domains for pairs of parameter (ξ, σ) and (σ, μ) are derived.

  15. Small Benefit from Country Size

    OpenAIRE

    Kazuto Masuda

    2010-01-01

    Furceri and Karras(2007, 2008) insisted that smaller countries are subject to more volatile business cycles than larger countries and country size really matters using international data from 1960 to 2000. They measure country size with population size. In this paper, we calculate welfare benefit from the less volatile busine! ss cycle, that is the positive effect of country size in Japan, US and OECD average. For calculating welfare benefit, we use “Welfare Cost of Business Cycle†approac...

  16. Small and mid-sized carnivores

    Science.gov (United States)

    Steven W. Buskirk; William J. Zielinski

    2003-01-01

    Small and mid-sized carnivores of western forests represent an ecologically diverse and influential guild of forest vertebrates. They comprise over a dozen species with varied life histories and habitat associations, highly species-specific responses to human-caused habitat change, and varied conservation status across western North America. Forested habitats fulfill...

  17. Wound size measurement of lower extremity ulcers using segmentation algorithms

    Science.gov (United States)

    Dadkhah, Arash; Pang, Xing; Solis, Elizabeth; Fang, Ruogu; Godavarty, Anuradha

    2016-03-01

    Lower extremity ulcers are one of the most common complications that not only affect many people around the world but also have huge impact on economy since a large amount of resources are spent for treatment and prevention of the diseases. Clinical studies have shown that reduction in the wound size of 40% within 4 weeks is an acceptable progress in the healing process. Quantification of the wound size plays a crucial role in assessing the extent of healing and determining the treatment process. To date, wound healing is visually inspected and the wound size is measured from surface images. The extent of wound healing internally may vary from the surface. A near-infrared (NIR) optical imaging approach has been developed for non-contact imaging of wounds internally and differentiating healing from non-healing wounds. Herein, quantitative wound size measurements from NIR and white light images are estimated using a graph cuts and region growing image segmentation algorithms. The extent of the wound healing from NIR imaging of lower extremity ulcers in diabetic subjects are quantified and compared across NIR and white light images. NIR imaging and wound size measurements can play a significant role in potentially predicting the extent of internal healing, thus allowing better treatment plans when implemented for periodic imaging in future.

  18. Genetics of Rapid and Extreme Size Evolution in Island Mice.

    Science.gov (United States)

    Gray, Melissa M; Parmenter, Michelle D; Hogan, Caley A; Ford, Irene; Cuthbert, Richard J; Ryan, Peter G; Broman, Karl W; Payseur, Bret A

    2015-09-01

    Organisms on islands provide a revealing window into the process of adaptation. Populations that colonize islands often evolve substantial differences in body size from their mainland relatives. Although the ecological drivers of this phenomenon have received considerable attention, its genetic basis remains poorly understood. We use house mice (subspecies: Mus musculus domesticus) from remote Gough Island to provide a genetic portrait of rapid and extreme size evolution. In just a few hundred generations, Gough Island mice evolved the largest body size among wild house mice from around the world. Through comparisons with a smaller-bodied wild-derived strain from the same subspecies (WSB/EiJ), we demonstrate that Gough Island mice achieve their exceptional body weight primarily by growing faster during the 6 weeks after birth. We use genetic mapping in large F(2) intercrosses between Gough Island mice and WSB/EiJ to identify 19 quantitative trait loci (QTL) responsible for the evolution of 16-week weight trajectories: 8 QTL for body weight and 11 QTL for growth rate. QTL exhibit modest effects that are mostly additive. We conclude that body size evolution on islands can be genetically complex, even when substantial size changes occur rapidly. In comparisons to published studies of laboratory strains of mice that were artificially selected for divergent body sizes, we discover that the overall genetic profile of size evolution in nature and in the laboratory is similar, but many contributing loci are distinct. Our results underscore the power of genetically characterizing the entire growth trajectory in wild populations and lay the foundation necessary for identifying the mutations responsible for extreme body size evolution in nature. Copyright © 2015 by the Genetics Society of America.

  19. Small domain-size multiblock copolymer electrolytes

    Science.gov (United States)

    Pistorino, Jonathan; Eitouni, Hany Basam

    2016-09-20

    New block polymer electrolytes have been developed which have higher conductivities than previously reported for other block copolymer electrolytes. The new materials are constructed of multiple blocks (>5) of relatively low domain size. The small domain size provides greater protection against formation of dendrites during cycling against lithium in an electrochemical cell, while the large total molecular weight insures poor long range alignment, which leads to higher conductivity. In addition to higher conductivity, these materials can be more easily synthesized because of reduced requirements on the purity level of the reagents.

  20. Small domain-size multiblock copolymer electrolytes

    Energy Technology Data Exchange (ETDEWEB)

    Pistorino, Jonathan; Eitouni, Hany Basam

    2016-09-20

    New block polymer electrolytes have been developed which have higher conductivities than previously reported for other block copolymer electrolytes. The new materials are constructed of multiple blocks (>5) of relatively low domain size. The small domain size provides greater protection against formation of dendrites during cycling against lithium in an electrochemical cell, while the large total molecular weight insures poor long range alignment, which leads to higher conductivity. In addition to higher conductivity, these materials can be more easily synthesized because of reduced requirements on the purity level of the reagents.

  1. 78 FR 11745 - Small Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small...

    Science.gov (United States)

    2013-02-20

    ... / Wednesday, February 20, 2013 / Rules and Regulations#0;#0; ] SMALL BUSINESS ADMINISTRATION 13 CFR Part 121 RIN 3245-AG46 Small Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small Business Technology Transfer (STTR) Program; Correction AGENCY: U.S. Small Business...

  2. Assessing Learning in Small Sized Physics Courses

    CERN Document Server

    Ene, Emanuela

    2015-01-01

    We describe the construction, validation and testing of a concept inventory for an Introduction to Physics of Semiconductors course offered by the department of physics for undergraduate engineering students. By design, this inventory addresses both content knowledge and ability to interpret content via different cognitive processes described in Bloom's taxonomy. The primary challenge comes from the low number of test takers. Since the Rasch Model (aka 1PL IRT model), can be used with small sample sizes, we describe Rasch Modeling analysis and results for this concept inventory.

  3. 76 FR 27935 - Small Business Size Standards: Transportation and Warehousing

    Science.gov (United States)

    2011-05-13

    ... business size standards. In this proposed rule, SBA has applied its methodology that pertains to... on Federal small businesses assistance. Size Standards Methodology SBA has prepared a ``Size... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS...

  4. 78 FR 70847 - Small Business Size Standards; Manufacturing; Correction

    Science.gov (United States)

    2013-11-27

    ... RIN 3245-AG47 Small Business Size Standards; Manufacturing; Correction AGENCY: U.S. Small Business... small business size standards. In FR Doc. 2012-19973 appearing on page 49991 of the August 20,...

  5. Penile size and the 'small penis syndrome'.

    Science.gov (United States)

    Wylie, Kevan R; Eardley, Ian

    2007-06-01

    The male is often troubled by concerns that his penis is not large enough to satisfy his partner or himself. He is ashamed to have others view his penis, especially in the flaccid state. Such concerns might be unfounded in reality and might be a presentation of social anxiety or some other clinical problem, such as erectile dysfunction. Concern over the size of the penis, when such concern becomes excessive, might present as the 'small penis syndrome', an obsessive rumination with compulsive checking rituals, body dysmorphic disorder, or as part of a psychosis. However, it is often a worry that can be described as within the normal experience of many men. Various potential causal factors are considered. A thorough assessment, normalizing the worry and then exploring the treatment options in detail with the man, is essential to allow the matter to be consolidated satisfactorily within the male ego.

  6. The Small Nuclear Genomes of Selaginella Are Associated with a Low Rate of Genome Size Evolution.

    Science.gov (United States)

    Baniaga, Anthony E; Arrigo, Nils; Barker, Michael S

    2016-06-03

    The haploid nuclear genome size (1C DNA) of vascular land plants varies over several orders of magnitude. Much of this observed diversity in genome size is due to the proliferation and deletion of transposable elements. To date, all vascular land plant lineages with extremely small nuclear genomes represent recently derived states, having ancestors with much larger genome sizes. The Selaginellaceae represent an ancient lineage with extremely small genomes. It is unclear how small nuclear genomes evolved in Selaginella We compared the rates of nuclear genome size evolution in Selaginella and major vascular plant clades in a comparative phylogenetic framework. For the analyses, we collected 29 new flow cytometry estimates of haploid genome size in Selaginella to augment publicly available data. Selaginella possess some of the smallest known haploid nuclear genome sizes, as well as the lowest rate of genome size evolution observed across all vascular land plants included in our analyses. Additionally, our analyses provide strong support for a history of haploid nuclear genome size stasis in Selaginella Our results indicate that Selaginella, similar to other early diverging lineages of vascular land plants, has relatively low rates of genome size evolution. Further, our analyses highlight that a rapid transition to a small genome size is only one route to an extremely small genome.

  7. 77 FR 13329 - Information Collection; Small Business Size Representation

    Science.gov (United States)

    2012-03-06

    ...; Small Business Size Representation AGENCIES: Department of Defense (DOD), General Services... representation. DATES: Submit comments on or before: May 7, 2012. ADDRESSES: Submit comments identified by Information Collection 9000- 0163, Small Business Size Representation, by any of the following methods...

  8. Small Black Holes and Near-Extremal CFTs

    CERN Document Server

    Benjamin, Nathan; Fitzpatrick, A Liam; Maloney, Alexander; Perlmutter, Eric

    2016-01-01

    Pure theories of AdS$_3$ quantum gravity are conjectured to be dual to CFTs with sparse spectra of light primary operators. The sparsest possible spectrum consistent with modular invariance includes only black hole states above the vacuum. Witten conjectured the existence of a family of extremal CFTs, which realize this spectrum for all admissible values of the central charge. We consider the quantum corrections to the classical spectrum, and propose a specific modification of Witten's conjecture which takes into account the existence of "small" black hole states. These have zero classical horizon area, with a calculable entropy attributed solely to loop effects. Our conjecture passes various consistency checks, especially when generalized to include theories with supersymmetry. In theories with $\\mathcal{N}=2$ supersymmetry, this "near-extremal CFT" proposal precisely evades the no-go results of Gaberdiel et al.

  9. How to conserve threatened Chinese plant species with extremely small populations?

    Directory of Open Access Journals (Sweden)

    Sergei Volis

    2016-02-01

    Full Text Available The Chinese flora occupies a unique position in global plant diversity, but is severely threatened. Although biodiversity conservation in China has made significant progress over the past decades, many wild plant species have extremely small population sizes and therefore are in extreme danger of extinction. The concept of plant species with extremely small populations (PSESPs, recently adopted and widely accepted in China, lacks a detailed description of the methodology appropriate for conserving PSESPs. Strategies for seed sampling, reintroduction, protecting PSESP locations, managing interactions with the local human population, and other conservation aspects can substantially differ from those commonly applied to non-PSESPs. The present review is an attempt to provide a detailed conservation methodology with realistic and easy-to-follow guidelines for PSESPs in China.

  10. Fake Superpotential for Large and Small Extremal Black Holes

    CERN Document Server

    Andrianopoli, L; Ferrara, S; Trigiante, M

    2010-01-01

    We consider the fist order, gradient-flow, description of the scalar fields coupled to spherically symmetric, asymptotically flat black holes in extended supergravities. Using the identification of the fake superpotential with Hamilton's characteristic function we clarify some of its general properties, showing in particular (besides reviewing the issue of its duality invariance) that W has the properties of a Liapunov's function, which implies that its extrema (associated with the horizon of extremal black holes) are asymptotically stable equilibrium points of the corresponding first order dynamical system (in the sense of Liapunov). Moreover, we show that the fake superpotential W has, along the entire radial flow, the same flat directions which exist at the attractor point. This allows to study properties of the ADM mass also for small black holes where in fact W has no critical points at finite distance in moduli space. In particular the W function for small non-BPS black holes can always be computed anal...

  11. Small and Medium-Sized Enterprises in Concern

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    @@ A common concern The outer environment At present,small and medium-sized enterprises are faced with many serious challenges.Since most of the large-sized enterprises ln China are state-owned ones,small and medium-sized enterprises in this article are referred mainly to those in the private sector.

  12. 76 FR 69154 - Small Business Size and Status Integrity

    Science.gov (United States)

    2011-11-08

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Parts 121, 124, 125, 126, and 127 RIN 3245-AG23 Small Business Size and Status Integrity... Business Jobs Act of 2010 (Jobs Act) pertaining to small business size and status integrity. SBA proposed...

  13. String Theory: Big Problem for Small Size

    Science.gov (United States)

    Sahoo, S.

    2009-01-01

    String theory is the most promising candidate theory for a unified description of all the fundamental forces that exist in nature. It provides a mathematical framework that combines quantum theory with Einstein's general theory of relativity. The typical size of a string is of the order of 10[superscript -33] cm, called the Planck length. But due…

  14. String Theory: Big Problem for Small Size

    Science.gov (United States)

    Sahoo, S.

    2009-01-01

    String theory is the most promising candidate theory for a unified description of all the fundamental forces that exist in nature. It provides a mathematical framework that combines quantum theory with Einstein's general theory of relativity. The typical size of a string is of the order of 10[superscript -33] cm, called the Planck length. But due…

  15. A practical and theoretical definition of very small field size for radiotherapy output factor measurements

    Energy Technology Data Exchange (ETDEWEB)

    Charles, P. H., E-mail: p.charles@qut.edu.au; Crowe, S. B.; Langton, C. M.; Trapp, J. V. [School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001 (Australia); Cranmer-Sargison, G. [Department of Medical Physics, Saskatchewan Cancer Agency, 20 Campus Dr., Saskatoon, Saskatchewan S7L 3P6, Canada and Academic Unit of Medical Physics, Faculty of Medicine and Health, University of Leeds, 8.001 Worsley Building, Leeds LS2 9JT (United Kingdom); Thwaites, D. I. [Institute of Medical Physics, School of Physics, University of Sydney, NSW 2006 (Australia); Kairn, T. [School of Chemistry, Physics and Mechanical Engineering, Queensland University of Technology, GPO Box 2434, Brisbane, QLD 4001, Australia and Premion, The Wesley Medical Centre, Suite 1, 40 Chasely St, Auchenflower, Brisbane, QLD 4066 (Australia); Knight, R. T. [Premion, The Wesley Medical Centre, Suite 1, 40 Chasely St, Auchenflower, Brisbane, QLD 4066 (Australia); Kenny, J. [The Australian Clinical Dosimetry Service, Australian Radiation Protection and Nuclear Safety Agency, 619 Lower Plenty Road, Yallambie, VIC 3085, Australia and Radiation Oncology Queensland, St Andrew' s Toowoomba Hospital, Toowoomba, QLD 4350 (Australia)

    2014-04-15

    Purpose: This work introduces the concept of very small field size. Output factor (OPF) measurements at these field sizes require extremely careful experimental methodology including the measurement of dosimetric field size at the same time as each OPF measurement. Two quantifiable scientific definitions of the threshold of very small field size are presented. Methods: A practical definition was established by quantifying the effect that a 1 mm error in field size or detector position had on OPFs and setting acceptable uncertainties on OPF at 1%. Alternatively, for a theoretical definition of very small field size, the OPFs were separated into additional factors to investigate the specific effects of lateral electronic disequilibrium, photon scatter in the phantom, and source occlusion. The dominant effect was established and formed the basis of a theoretical definition of very small fields. Each factor was obtained using Monte Carlo simulations of a Varian iX linear accelerator for various square field sizes of side length from 4 to 100 mm, using a nominal photon energy of 6 MV. Results: According to the practical definition established in this project, field sizes ≤15 mm were considered to be very small for 6 MV beams for maximal field size uncertainties of 1 mm. If the acceptable uncertainty in the OPF was increased from 1.0% to 2.0%, or field size uncertainties are 0.5 mm, field sizes ≤12 mm were considered to be very small. Lateral electronic disequilibrium in the phantom was the dominant cause of change in OPF at very small field sizes. Thus the theoretical definition of very small field size coincided to the field size at which lateral electronic disequilibrium clearly caused a greater change in OPF than any other effects. This was found to occur at field sizes ≤12 mm. Source occlusion also caused a large change in OPF for field sizes ≤8 mm. Based on the results of this study, field sizes ≤12 mm were considered to be theoretically very small for 6

  16. Brain size and ecology in small mammals and primates.

    OpenAIRE

    1980-01-01

    Comparisons of brain-body size relationships within small mammal and primate families reveal intergeneric differences related to diet and foraging strategy. These same associations between relative brain size and ecology are also evident among interfamily comparisons.

  17. The Gravity and Extreme Magnetism Small Explorer (GEMS)

    Science.gov (United States)

    Kallman, T. R.

    2011-01-01

    The Gravity and Extreme Magnetism Small Explorer (GEMS) was selected by NASA for flight in 2014 to make a sensitive search for X-ray polarization from a wide set of source classes, including stellar black holes, Seyfert galaxies and quasars, blazars, rotation and accretion-powered pulsars, magnetars, shell supernova remnants and pulsar wind nebulae. Among the primary scientific objectives are determining the effects of the spin of black holes and the geometry of supermassive black hole accretion, determining the configurations of the magnetic fields and the X-ray emission of magnetars, and determining the magnetic structure of the supernova shocks in which cosmic rays are accelerated. GEMS will observe 23 targets during a 16 month prime mission, in observations that will be able to reach predicted levels of polarization. The mission can be extended to provide a guest observer phase. The GEMS instrument has time projection chamber polarimeters with high 2-10 keV efficiency at the focus of thin foil mirrors. The 4.5 m focal length mirrors will be deployed on an extended boom. The spacecraft with the instrument is rotated with a period of about 10 minutes to enable measurement and correction of systematic errors. A small Bragg reflection soft X-ray experiment takes advantage of this rotation to obtain a measurement at 0.5 keV. The design of the GEMS instrument and the mission, the expected performance and the planned science program will be discussed.

  18. How big is big and how small is small the sizes of everything and why

    CERN Document Server

    Smith, Timothy Paul

    2013-01-01

    This book is about how big is the universe and how small are quarks, and what are the sizes of dozens of things between these two extremes. It describes the sizes of atoms and planets, quarks and galaxies, cells and sequoias. It is a romp through forty-five orders of magnitude from the smallest sub-nuclear particles we have measured, to the edge of the observed universe. It also looks at time, from the epic age of the cosmos to the fleeting lifetimes of ethereal particles. It is a narrative that trips its way from stellar magnitudes to the clocks on GPS satellites, from the nearly logarithmic scales of a piano keyboard through a system of numbers invented by Archimedes and on to the measurement of the size of an atom. Why do some things happen at certain scales? Why are cells a hundred thousandths of a meter across? Why are stars never smaller than about 100 million meters in diameter? Why are trees limited to about 120 meters in height? Why are planets spherical, but asteroids not? Often the size of an objec...

  19. On bootstrap sample size in extreme value theory

    NARCIS (Netherlands)

    J.L. Geluk (Jaap); L.F.M. de Haan (Laurens)

    2002-01-01

    textabstractIt has been known for a long time that for bootstrapping the probability distribution of the maximum of a sample consistently, the bootstrap sample size needs to be of smaller order than the original sample size. See Jun Shao and Dongsheng Tu (1995), Ex. 3.9,p. 123. We show that the same

  20. 76 FR 8221 - Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status...

    Science.gov (United States)

    2011-02-11

    ... February 11, 2011 Part VII Small Business Administration 13 CFR Parts 121 and 124 Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status Determinations; Final Rule #0;#0... BUSINESS ADMINISTRATION 13 CFR Parts 121 and 124 RIN 3245-AF53 Small Business Size Regulations; 8(a...

  1. Size variation in small-bodied humans from palau, micronesia.

    Directory of Open Access Journals (Sweden)

    Andrew Gallagher

    Full Text Available BACKGROUND: Recent discoveries on Palau are claimed to represent the remains of small-bodied humans that may display evidence insular size reduction. This claim has yet to be statistically validated METHODOLOGY/PRINCIPAL FINDINGS: Published postcranial specimens (n = 16 from Palau were assessed relative to recent small-bodied comparative samples. Resampling statistical approaches were employed to test specific hypotheses relating to body size in the Palau sample. Results confirm that the Palau postcranial sample is indisputably small-bodied. CONCLUSIONS/SIGNIFICANCE: A single, homogenous body size morph is represented in early prehistoric postcrania from Palau. Small body size in early Palauans is an ancestral characteristic and was likely not a consequence of in-situ size reduction. Specimens from Palau have little bearing upon hypothesised insular size reduction in the ancestral lineage of Homo floresiensis.

  2. 76 FR 70667 - Small Business Size Standards: Educational Services

    Science.gov (United States)

    2011-11-15

    ..., SBA establishes small business size definitions (referred to as size standards) for private sector... agencies. SBA also makes periodic inflation adjustments to its monetary based size standards. SBA's latest... Administration's current policies, suggestions from industry groups and Federal agencies, and public comments on...

  3. Laws of small numbers extremes and rare events

    CERN Document Server

    Falk, Michael; Hüsler, Jürg

    2004-01-01

    Since the publication of the first edition of this seminar book in 1994, the theory and applications of extremes and rare events have enjoyed an enormous and still increasing interest. The intention of the book is to give a mathematically oriented development of the theory of rare events underlying various applications. This characteristic of the book was strengthened in the second edition by incorporating various new results on about 130 additional pages. Part II, which has been added in the second edition, discusses recent developments in multivariate extreme value theory. Particularly notable is a new spectral decomposition of multivariate distributions in univariate ones which makes multivariate questions more accessible in theory and practice. One of the most innovative and fruitful topics during the last decades was the introduction of generalized Pareto distributions in the univariate extreme value theory. Such a statistical modelling of extremes is now systematically developed in the multivariate fram...

  4. 75 FR 61597 - Small Business Size Standards: Retail Trade

    Science.gov (United States)

    2010-10-06

    .... Technology, productivity growth, international competition, mergers and acquisitions, and updated industry... of size standards by deleting the last sentence and replacing it with ``Acquisitions for supplies... economic advantage over their larger counterparts, the Small Business Act authorizes the SBA Administrator...

  5. Information Security in Small and Medium-Sized Companies

    OpenAIRE

    David Kral

    2011-01-01

    Information security doesn’t involve only large organizations. Small and medium-sized companies must closely examine this issue too, because they are increasingly threatened by cyber attacks. Many of them mistakenly believe, that security of their valuable data is sufficient, or that the attackers are not interested in them. Existing standards and methodologies for implementation and management of information security are often hard to transfer to the environment of small and medium-sized bus...

  6. 77 FR 28237 - Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status...

    Science.gov (United States)

    2012-05-14

    ... / Monday, May 14, 2012 / Rules and Regulations#0;#0; ] SMALL BUSINESS ADMINISTRATION 13 CFR Part 124 RIN 3245-AF53 Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status Determinations; Correction AGENCY: U.S. Small Business Administration. ACTION: Correcting...

  7. 75 FR 1296 - Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status...

    Science.gov (United States)

    2010-01-11

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Parts 121 and 124 Small Business Size Regulations; 8(a) Business Development/Small Disadvantaged Business Status Determinations AGENCY: U.S. Small Business Administration. ACTION: Notice of...

  8. The causal effect of board size in the performance of small and medium-sized firms

    DEFF Research Database (Denmark)

    Bennedsen, Morten; Kongsted, Hans Christian; Meisner Nielsen, Kasper

    2008-01-01

    correlation between family size and board size and show this correlation to be driven by firms where the CEO's relatives serve on the board. Second, we find empirical evidence of a small adverse board size effect driven by the minority of small and medium-sized firms that are characterized by having......Empirical studies of large publicly traded firms have shown a robust negative relationship between board size and firm performance. The evidence on small and medium-sized firms is less clear; we show that existing work has been incomplete in analyzing the causal relationship due to weak...... identification strategies. Using a rich data set of almost 7000 closely held corporations we provide a causal analysis of board size effects on firm performance: We use a novel instrument given by the number of children of the chief executive officer (CEO) of the firms. First, we find a strong positive...

  9. Small black holes and near-extremal CFTs

    Energy Technology Data Exchange (ETDEWEB)

    Benjamin, Nathan; Dyer, Ethan [Stanford Institute for Theoretical Physics,Via Pueblo, Stanford, CA 94305 (United States); Fitzpatrick, A. Liam [Boston University Physics Department,Commonwealth Avenue, Boston, MA 02215 (United States); Maloney, Alexander [McGill Physics Department,3600 rue University, Montréal, QC H3A 2T8 (Canada); Perlmutter, Eric [Department of Physics, Princeton University,Jadwin Hall, Princeton, NJ 08544 (United States)

    2016-08-02

    Pure theories of AdS{sub 3} quantum gravity are conjectured to be dual to CFTs with sparse spectra of light primary operators. The sparsest possible spectrum consistent with modular invariance includes only black hole states above the vacuum. Witten conjectured the existence of a family of extremal CFTs, which realize this spectrum for all admissible values of the central charge. We consider the quantum corrections to the classical spectrum, and propose a specific modification of Witten’s conjecture which takes into account the existence of “small” black hole states. These have zero classical horizon area, with a calculable entropy attributed solely to loop effects. Our conjecture passes various consistency checks, especially when generalized to include theories with supersymmetry. In theories with N=2 supersymmetry, this “near-extremal CFT” proposal precisely evades the no-go results of Gaberdiel et al.

  10. Holonic Business Process Modeling in Small to Medium Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Nur Budi Mulyono

    2012-01-01

    Full Text Available Holonic modeling analysis which is the application of system thinking in design, manage, and improvement, is used in a novel context for business process modeling. An approach and techniques of holon and holarchies is presented specifically for small and medium sized enterprise process modeling development. The fitness of the approach is compared with well known reductionist or task breakdown approach. The strength and weaknesses of the holonic modeling is discussed with illustrating case example in term of its suitability for an Indonesia’s small and medium sized industry. The novel ideas in this paper have great impact on the way analyst should perceive business process. Future research is applying the approach in supply chain context.Key words: Business process, holonic modeling, operations management, small to medium sized enterprise

  11. New small-size peptides possessing antifungal activity

    NARCIS (Netherlands)

    Garibotto, Francisco M.; Garro, Adriana D.; Masman, Marcelo F.; Rodriguez, Ana M.; Luiten, Paul G. M.; Raimondi, Marcela; Zacchino, Susana A.; Somlai, Csaba; Penke, Botond; Enriz, Ricardo D.

    2010-01-01

    The synthesis, in vitro evaluation, and conformational study of a new series of small-size peptides acting as antifungal agents are reported. In a first step of our study we performed a conformational analysis using Molecular Mechanics calculations. The electronic study was carried out using Molecul

  12. 77 FR 39385 - Receipts-Based, Small Business Size Standard

    Science.gov (United States)

    2012-07-03

    ... Federal Regulations is sold by the Superintendent of Documents. #0;Prices of new books are listed in the...), the NRC conformed its format for size standards to mirror the definitions of small entities in the... reactors, Penalties, Sex discrimination, Source material, Special nuclear material, Waste treatment...

  13. Workplace Health Promotion within Small and Medium-Sized Enterprises

    Science.gov (United States)

    Moore, Ann; Parahoo, Kader; Fleming, Paul

    2010-01-01

    Purpose: The purpose of this study is to explore managers' understanding of workplace health promotion (WHP) and experiences of WHP activity within small and medium-sized enterprises (SMEs) in a Health and Social Care Trust area of Northern Ireland. The paper aims to focus on engagement with activities within the context of prevention of…

  14. Small-scale characteristics of extremely high latitude aurora

    Directory of Open Access Journals (Sweden)

    J. A. Cumnock

    2009-09-01

    Full Text Available We examine 14 cases of an interesting type of extremely high latitude aurora as identified in the precipitating particles measured by the DMSP F13 satellite. In particular we investigate structures within large-scale arcs for which the particle signatures are made up of a group of multiple distinct thin arcs. These cases are chosen without regard to IMF orientation and are part of a group of 87 events where DMSP F13 SSJ/4 measures emissions which occur near the noon-midnight meridian and are spatially separated from both the dawnside and duskside auroral ovals by wide regions with precipitating particles typical of the polar cap. For 73 of these events the high-latitude aurora consists of a continuous region of precipitating particles. We focus on the remaining 14 of these events where the particle signatures show multiple distinct thin arcs. These events occur during northward or weakly southward IMF conditions and follow a change in IMF By. Correlations are seen between the field-aligned currents and plasma flows associated with the arcs, implying local closure of the FACs. Strong correlations are seen only in the sunlit hemisphere. The convection associated with the multiple thin arcs is localized and has little influence on the large-scale convection. This also implies that the sunward flow along the arcs is unrelated to the overall ionospheric convection.

  15. 77 FR 30227 - Small Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small...

    Science.gov (United States)

    2012-05-22

    ... (SBIR) Program and Small Business Technology Transfer (STTR) Program AGENCY: U.S. Small Business... (SBIR) and Small Business Technology Transfer (STTR) Programs. The proposed rule would implement... technological constraints, participation is limited to 125 registrants for the Webinar. If demand...

  16. The Gravity and Extreme Magnetism Small Expolorer Mission

    Science.gov (United States)

    Kallman, Timothy R.; Swank, J.; Jahoda, K.; GEMS Team

    2011-01-01

    Polarization is an inherently geometric quantity and provides information on source geometry inaccessible via spectroscopy or timing. To date, there have been reliable detections of X-ray polarization from only one object outside the solar system (the Crab nebula). Recent development of photoelectric polarimetry makes it possible to perform sensitive X-ray polarimetry with a modest mission. GEMS was recently selected by NASA to be the 13th Small Explorer mission with launch planned for 2014. GEMS will be 100× more sensitive than any previously flown X-ray polarimeter and should provide useful polarization measurements for dozens of sources, to lower than predicted levels. GEMS will lead to new insights into the nature of accreting black holes, highly magnetized neutron stars, and supernova remnants.

  17. Estimation of individual reference intervals in small sample sizes

    DEFF Research Database (Denmark)

    Hansen, Ase Marie; Garde, Anne Helene; Eller, Nanna Hurwitz

    2007-01-01

    of that order of magnitude for all topics in question. Therefore, new methods to estimate reference intervals for small sample sizes are needed. We present an alternative method based on variance component models. The models are based on data from 37 men and 84 women taking into account biological variation...... presented in this study. The presented method enables occupational health researchers to calculate reference intervals for specific groups, i.e. smokers versus non-smokers, etc. In conclusion, the variance component models provide an appropriate tool to estimate reference intervals based on small sample...

  18. Unusual allometry for sexual size dimorphism in a cichlid where males are extremely larger than females

    Indian Academy of Sciences (India)

    Kazutaka Ota; Masanori Kohda; Tetsu Sato

    2010-06-01

    When males are the larger sex, a positive allometric relationship between male and female sizes is often found across populations of a single species (i.e. Rensch’s rule). This pattern is typically explained by a sexual selection pressure on males. Here, we report that the allometric relationship was negative across populations of a shell-brooding cichlid fish Lamprologus callipterus, although males are extremely larger than females. Male L. callipterus collect and defend empty snail shells in each of which a female breeds. We found that, across six populations, male and female sizes are positively correlated with not only sexual and fecundity selection indices, but also with shell sizes. Given their different reproductive behaviours, these correlations mean that males are required to be more powerful, and thus larger, to transport larger shells, while female bodies are reduced to the shell size to enable them to enter the shells. Among the three size selections (sexual selection, fecundity selection and shell size), shell size explained the allometry, suggesting that females are more strongly subject to size selection associated with shell size availability than males. However, the allometry was violated when considering an additional population where size-selection regimes of males differed from that of other populations. Therefore, sexual size allometry will be violated by body size divergence induced by multiple selection regimes.

  19. Sales strategy in small and medium-sized food companies

    DEFF Research Database (Denmark)

    2002-01-01

    All managing teams know that they have to deal with the company's strategy in handling the market. But how do they do it and on the basis of which beleifs and interpretations? A nearly completed PhD project has examined the way in which three small and medium-sized food companies define...... their market, their competitors and customers, and how they create the world they perceive and act in through their own actions....

  20. Holonic Business Process Modeling in Small to Medium Sized Enterprises

    OpenAIRE

    Nur Budi Mulyono; Tezar Yuliansyah Saputra; Nur Arief Rahmatsyah

    2012-01-01

    Holonic modeling analysis which is the application of system thinking in design, manage, and improvement, is used in a novel context for business process modeling. An approach and techniques of holon and holarchies is presented specifically for small and medium sized enterprise process modeling development. The fitness of the approach is compared with well known reductionist or task breakdown approach. The strength and weaknesses of the holonic modeling is discussed with illustrating case exa...

  1. Unions in small and medium-sized enterprises

    DEFF Research Database (Denmark)

    Holten, Ann-Louise; Crouch, Colin

    2014-01-01

    Trade unions are commonly weak in small- and medium-sized enterprises, which constitute a majority of European firms and are often family-owned. We investigate the influence of family ownership on employee membership, perceptions and experience with unions in Danish and Italian firms in the textile...... and clothing sector. Family ownership reduces union membership; and within family firms, the number of family members employed is negatively associated with unionization rates and employee perceptions of unions....

  2. Performance measuring of tourism small medium-sized enterprises

    OpenAIRE

    Anca Borza; Ovidiu Bordean

    2006-01-01

    The article analyzes the performance measurement processes within the small medium-sized enterprises that run businesses in Romania's tourism sector. Related to contemporary approaches to improving business performance in the management literature, performance measurement approaches are analyzed using the balanced scorecard framework. Balanced scorecards proved to be a powerful tool that can inform the managers about the things that are working or not within a company, what is to be improved ...

  3. ERP adoption in small and medium sized enterprises

    OpenAIRE

    Juell-Skielse, Gustaf

    2006-01-01

    Enterprise resource planning (ERP) is established among a majority of small and medium sized companies in Kista Science City and seems to have a positive effect on organizational effectiveness. Kista Science City is Sweden’s largest corporate centre, with more companies and employees in a limited area than anywhere else in Europe. This study looks at the level of adoption of ERP functions, perceived organizational effectiveness and critical success factors. The most common use of ERP is for f...

  4. Small RNA transcriptomes of mangroves evolve adaptively in extreme environments.

    Science.gov (United States)

    Wen, Ming; Lin, Xingqin; Xie, Munan; Wang, Yushuai; Shen, Xu; Liufu, Zhongqi; Wu, Chung-I; Shi, Suhua; Tang, Tian

    2016-01-01

    MicroRNAs (miRNAs) and endogenous small interfering RNAs (siRNAs) are key players in plant stress responses. Here, we present the sRNA transcriptomes of mangroves Bruguiera gymnorrhiza and Kandelia candel. Comparative computational analyses and target predictions revealed that mangroves exhibit distinct sRNA regulatory networks that differ from those of glycophytes. A total of 32 known and three novel miRNA families were identified. Conserved and mangrove-specific miRNA targets were predicted; the latter were widely involved in stress responses. The known miRNAs showed differential expression between the mangroves and glycophytes, reminiscent of the adaptive stress-responsive changes in Arabidopsis. B. gymnorrhiza possessed highly abundant but less conserved TAS3 trans-acting siRNAs (tasiRNAs) in addition to tasiR-ARFs, with expanded potential targets. Our results indicate that the evolutionary alteration of sRNA expression levels and the rewiring of sRNA-regulatory networks are important mechanisms underlying stress adaptation. We also identified sRNAs that are involved in salt and/or drought tolerance and nutrient homeostasis as possible contributors to mangrove success in stressful environments.

  5. Litter size variation in Polish selected small dog breeds

    Directory of Open Access Journals (Sweden)

    Małgorzata Goleman

    2015-08-01

    Full Text Available In breeders’ general opinion small breed females produce less numerous litters. The aim of the study was to analyse the litter size and the frequency of the gender ratio in selected small dog breeds in view of their popularity in Poland. The data set comprised information on 639 litters (in total 2578 puppies of eight breeds, which were born between January 2003 and end December 2014. The results were statistically analysed using statistical program SPSS 20.0. Medium-size litters were observed in the analysed small dog breeds (4.034±0.1. Comparison of the selected breeds of the Fédération Cynologique Internationale (FCI Groups showed that the mean litter size in Group IX was higher (4.36±0.08 than that in Group III (3.87±0.14 and the differences were statistically significant. The study has confirmed the hypothesis that larger females produce more numerous litters, but there are large intra-individual variations in the number of pups born in individual breeds. Additionally, the gender ratio in the puppies born in the analysed breeds was equal, despite the fluctuations in the individual breeds.

  6. Significance assessment of small-medium sized reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kanno, Minoru [Japan Atomic Power Co., Research and Development Dept., Tokyo (Japan)

    2002-12-01

    Preliminary assessment for deployment of small-medium sized reactor (S and M reactor) as a future option has been conducted at the JAPCO (Japan Atomic Power Company) under the cooperation with the CRIERI (Central Research Institute of Electric Power Industry). Significance of the S and M reactor introduction is listed as follows; lower investment cost, possible siting near demand side, enlarged freedom of siting, shorter transmission line, good compatibility with slow increase of demand and plain explanation of safety using simpler system such as integral type vessel without piping, natural convection core cooling and passive safety system. The deployment of simpler plant system, modular shop fabrication, ship-shell structured building and longer operation period can assure economics comparable with that of a large sized reactor, coping with scale-demerit. Also the S and M reactor is preferable in size for the nuclear heat utilization such as hydrogen production. (T. Tanaka)

  7. Significance assessment of small-medium sized reactors

    Energy Technology Data Exchange (ETDEWEB)

    Kanno, Minoru [Japan Atomic Power Co., Research and Development Dept., Tokyo (Japan)

    2002-12-01

    Preliminary assessment for deployment of small-medium sized reactor (S and M reactor) as a future option has been conducted at the JAPCO (Japan Atomic Power Company) under the cooperation with the CRIERI (Central Research Institute of Electric Power Industry). Significance of the S and M reactor introduction is listed as follows; lower investment cost, possible siting near demand side, enlarged freedom of siting, shorter transmission line, good compatibility with slow increase of demand and plain explanation of safety using simpler system such as integral type vessel without piping, natural convection core cooling and passive safety system. The deployment of simpler plant system, modular shop fabrication, ship-shell structured building and longer operation period can assure economics comparable with that of a large sized reactor, coping with scale-demerit. Also the S and M reactor is preferable in size for the nuclear heat utilization such as hydrogen production. (T. Tanaka)

  8. Oligomeric viral proteins: small in size, large in presence

    Science.gov (United States)

    Jayaraman, Bhargavi; Smith, Amber M.; Fernandes, Jason D.; Frankel, Alan D.

    2016-01-01

    Viruses are obligate parasites that rely heavily on host cellular processes for replication. The small number of proteins typically encoded by a virus is faced with selection pressures that lead to the evolution of distinctive structural properties, allowing each protein to maintain its function under constraints such as small genome size, high mutation rate, and rapidly changing fitness conditions. One common strategy for this evolution is to utilize small building blocks to generate protein oligomers that assemble in multiple ways, thereby diversifying protein function and regulation. In this review, we discuss specific cases that illustrate how oligomerization is used to generate a single defined functional state, to modulate activity via different oligomeric states, or to generate multiple functional forms via different oligomeric states. PMID:27685368

  9. Undersampling power-law size distributions: effect on the assessment of extreme natural hazards

    Science.gov (United States)

    Geist, Eric L.; Parsons, Thomas E.

    2014-01-01

    The effect of undersampling on estimating the size of extreme natural hazards from historical data is examined. Tests using synthetic catalogs indicate that the tail of an empirical size distribution sampled from a pure Pareto probability distribution can range from having one-to-several unusually large events to appearing depleted, relative to the parent distribution. Both of these effects are artifacts caused by limited catalog length. It is more difficult to diagnose the artificially depleted empirical distributions, since one expects that a pure Pareto distribution is physically limited in some way. Using maximum likelihood methods and the method of moments, we estimate the power-law exponent and the corner size parameter of tapered Pareto distributions for several natural hazard examples: tsunamis, floods, and earthquakes. Each of these examples has varying catalog lengths and measurement thresholds, relative to the largest event sizes. In many cases where there are only several orders of magnitude between the measurement threshold and the largest events, joint two-parameter estimation techniques are necessary to account for estimation dependence between the power-law scaling exponent and the corner size parameter. Results indicate that whereas the corner size parameter of a tapered Pareto distribution can be estimated, its upper confidence bound cannot be determined and the estimate itself is often unstable with time. Correspondingly, one cannot statistically reject a pure Pareto null hypothesis using natural hazard catalog data. Although physical limits to the hazard source size and by attenuation mechanisms from source to site constrain the maximum hazard size, historical data alone often cannot reliably determine the corner size parameter. Probabilistic assessments incorporating theoretical constraints on source size and propagation effects are preferred over deterministic assessments of extreme natural hazards based on historic data.

  10. Anthropometric Assessment in Children with Small Size at Birth

    Directory of Open Access Journals (Sweden)

    Nurdelkis Figueredo Rodríguez

    2013-07-01

    Full Text Available Background: development of anthropometric techniques and its close relation to diagnostic researches on various non-communicable chronic diseases has allowed predicting, to a certain extent, the progress of those infants with growth retardation due to several factors. Objective: to assess the effect of small size at birth on the evolution of the classic anthropometric variables during the first year of life. Methods: a longitudinal and prospective cohort study was conducted with live-born infants in the Eusebio Hernández Maternity Hospital of the municipality of Playa in January 2011. Variables analyzed included: weight, height, body circumferences and skinfolds. Physical examination was used to measure each individual. Measurements at birth were gathered from medical records. Subsequently, they were followed up in the nutrition consultation of the Juan M. Márquez Pediatric Hospital. Results: the two groups presented similar growth patterns over time. Largest final growth was observed in the group of normal size infants: skinfolds showed greater variation. Only the mid-upper arm circumference showed significantly different patterns of change between the groups. Conclusions: the study group showed no significant influence of small size at birth on the evolution of the classic anthropometric variables during the first year of life.

  11. The Small Size Debris Population at GEO from Optical Observations

    Science.gov (United States)

    Seitzer, Patrick; Barker, Ed; Buckalew, Brent; Burkhardt, Andrew; Cowardin, Heather; Frith, James; Kaleida, Catherine; Lederer, Susan M.; Lee, Chris H.

    2017-01-01

    We have observed the geosynchronous orbit (GEO) debris population at sizes smaller than 10 cm using optical observations with the 6.5-m Magellan telescope 'Walter Baade' at the Las Campanas Observatory in Chile. The IMACS f/2 imaging camera with a 0.5-degree diameter field of view has been used in small area surveys of the GEO regime to study the population of optically faint GEO debris. The goal is to estimate the population of GEO debris that is fainter than can be studied with 1-meter class telescopes. A significant population of objects fainter than R = 19th magnitude has been found. These objects have observed with angular rates consistent with circular orbits and orbital inclinations up to 15 degrees at GEO. A sizeable number of these objects have significant brightness variations ("flashes") during the 5-second exposure, which suggest rapid changes in the albedo-projected size product.

  12. Walking control of small size humanoid robot: HAJIME ROBOT 18

    Science.gov (United States)

    Sakamoto, Hajime; Nakatsu, Ryohei

    2007-12-01

    HAJIME ROBOT 18 is a fully autonomous biped robot. It has been developed for RoboCup which is a worldwide soccer competition of robots. It is necessary for a robot to have high mobility to play soccer. High speed walking and all directional walking are important to approach and to locate in front of a ball. HAJIME ROBOT achieved these walking. This paper describes walking control of a small size humanoid robot 'HAJIME ROBOT 18' and shows the measurement result of ZMP (Zero Moment Point). HAJIME ROBOT won the Robotics Society of Japan Award in RoboCup 2005 and in RoboCup 2006 Japan Open.

  13. Response to recurrent selection under small effective population size

    Directory of Open Access Journals (Sweden)

    Souza Jr. Cláudio Lopes de

    2000-01-01

    Full Text Available A formula was derived for the prediction of the response to recurrent selection when the effective population size (Ne is small. Usually, responses to selection have been estimated by Rs = icsigma²A/sigmaPh, where i, c, sigma²A, and sigmaPh stand for standardized selection differential, parental control, additive variance, and phenotypic standard deviation, respectively. This expression, however, was derived under the assumption of infinite population size. By introducing the effects of finite population size, the expression derived was Rs = [ic(sigma²A + deltaFD1/sigmaPh] - DFID, where deltaF, ID and D1 are the changes in the inbreeding coefficient, the inbreeding depression, and the covariance of additive and homozygous dominance effects, respectively. Thus, the predicted responses to selection based on these expressions will be smaller than those based on the standard procedures for traits with a high level of dominance such as yield. Responses to five cycles of half-sib selection were predicted for maize by both expressions, considering that 100 progenies were evaluated and 10 S1 progenies were recombined, which corresponds to Ne = 10 for each cycle. The accumulated response to selection estimated with the new expression was about 47 and 28% smaller than that based on the standard expression for yield and plant height, respectively. Thus, the expression usually used overestimates the responses to selection, which is in agreement with reported results, because it does not take into account the effective population size that is generally small in recurrent selection programs

  14. 77 FR 76215 - Small Business Size Regulations, Small Business Innovation Research (SBIR) Program and Small...

    Science.gov (United States)

    2012-12-27

    ... that the National Institutes of Health, Department of Energy, and the National Science Foundation may... NAICS 541711, Research and Development in Biotechnology, and NAICS 541712, Research and Development in the Physical, Engineering and Life Sciences (except Biotechnology) have 500 employee size...

  15. The spatial distribution of threats to plant species with extremely small populations

    Science.gov (United States)

    Wang, Chunjing; Zhang, Jing; Wan, Jizhong; Qu, Hong; Mu, Xianyun; Zhang, Zhixiang

    2016-04-01

    Many biological conservationists take actions to conserve plant species with extremely small populations (PSESP) in China; however, there have been few studies on the spatial distribution of threats to PSESP. Hence, we selected distribution data of PSESP and made a map of the spatial distribution of threats to PSESP in China. First, we used the weight assignment method to evaluate the threat risk to PSESP at both country and county scales. Second, we used a geographic information system to map the spatial distribution of threats to PSESP, and explored the threat factors based on linear regression analysis. Finally, we suggested some effective conservation options. We found that the PSESP with high values of protection, such as the plants with high scientific research values and ornamental plants, were threatened by over-exploitation and utilization, habitat fragmentation, and a small sized wild population in broad-leaved forests and bush fallows. We also identified some risk hotspots for PSESP in China. Regions with low elevation should be given priority for ex- and in-situ conservation. Moreover, climate change should be considered for conservation of PSESP. To avoid intensive over-exploitation or utilization and habitat fragmentation, in-situ conservation should be practiced in regions with high temperatures and low temperature seasonality, particularly in the high risk hotspots for PSESP that we proposed. Ex-situ conservation should be applied in these same regions, and over-exploitation and utilization of natural resources should be prevented. It is our goal to apply the concept of PSESP to the global scale in the future.

  16. The spatial distribution of threats to plant species with extremely small populations

    Science.gov (United States)

    Wang, Chunjing; Zhang, Jing; Wan, Jizhong; Qu, Hong; Mu, Xianyun; Zhang, Zhixiang

    2017-03-01

    Many biological conservationists take actions to conserve plant species with extremely small populations (PSESP) in China; however, there have been few studies on the spatial distribution of threats to PSESP. Hence, we selected distribution data of PSESP and made a map of the spatial distribution of threats to PSESP in China. First, we used the weight assignment method to evaluate the threat risk to PSESP at both country and county scales. Second, we used a geographic information system to map the spatial distribution of threats to PSESP, and explored the threat factors based on linear regression analysis. Finally, we suggested some effective conservation options. We found that the PSESP with high values of protection, such as the plants with high scientific research values and ornamental plants, were threatened by over-exploitation and utilization, habitat fragmentation, and a small sized wild population in broad-leaved forests and bush fallows. We also identified some risk hotspots for PSESP in China. Regions with low elevation should be given priority for ex- and in-situ conservation. Moreover, climate change should be considered for conservation of PSESP. To avoid intensive over-exploitation or utilization and habitat fragmentation, in-situ conservation should be practiced in regions with high temperatures and low temperature seasonality, particularly in the high risk hotspots for PSESP that we proposed. Ex-situ conservation should be applied in these same regions, and over-exploitation and utilization of natural resources should be prevented. It is our goal to apply the concept of PSESP to the global scale in the future.

  17. Incident Response Plan for a Small to Medium Sized Hospital

    Directory of Open Access Journals (Sweden)

    Charles DeVoe

    2013-04-01

    Full Text Available Most small to medium health care organizations do not have the capability to address cyber incidents within the organization.Those that do are poorly trained and ill equipped .These health care organizations are subject to various laws that address privacy concerns , proper handling of financial information, and Person ally Identifiable Information. Currently an IT staff handles responses to these incidents in an Ad Hoc manner.A properly trained, staffed,and equipped Cyber Incident Response Team is needed to quickly respond to these incidents to minimize data loss, and provide forensic data for the purpose of notification, disciplinary action, legal action, and to remove the risk vector. This paper 1 will use the proven Incident Command System model used in emergency services to show any sized agency can have an a dequate CIRT.

  18. Entrepreneurial Orientation vs. Innovativeness of Small and Medium Size Enterprises

    Directory of Open Access Journals (Sweden)

    Joanna Ejdys

    2016-01-01

    Full Text Available This study aims to examine the role of entrepreneurial orientation (entrepreneurship orientation in innovation level among Small and Medium Size Enterprises (SMEs. A questionnaire survey was conducted among 137 firms in the Podlaskie Region. Three hypotheses related to entrepreneurial orientation and innovativeness level were examined by Structural Equation Modeling (SEM. The relation between two constructs of entrepreneurial orientation and innovativeness, that is proactiveness and risk taking were analyzed. The research results show that proactiveness has a significant positive total effect on improving innovativeness. The findings suggest, in contrast to the strategic orientation literature, that risk taking deters enterprises from organizational innovation. The results confirmed the significantly higher impact of the risk taking as an intermediate variable on the innovation through the mediator of proactivity. This work examines the relations between entrepreneurial orientation and innovativeness, thus contributes to the strategic orientation literature.

  19. Variability management challenges in small and medium sized enterprises (SMEs

    Directory of Open Access Journals (Sweden)

    Tuomas Ihme

    2015-09-01

    Full Text Available Variability has become important means to provide customer specific products fast to the market. This paper presents findings from a literature study and questionnaire designed to find out the current variability management practices, challenges and needs in small and medium sized companies (SMEs. The literature study was carried out first, and based on its findings questionnaire study was designed and carried out. Transparency of variability and design decisions between R and D and business and customer interfaces and transparency of variability and design decisions within R and D were the most important and challenging variability areas in the studied organisations. The most frequently used architecture design issue was the use of known architectural styles and patterns to handle variability. The findings of the most challenging and important variability management topics, as well as the important improvement goals can be used to direct future research, and efforts to support companies in variability management.

  20. SIMPLIFIED MATHEMATICAL MODEL OF SMALL SIZED UNMANNED AIRCRAFT VEHICLE LAYOUT

    Directory of Open Access Journals (Sweden)

    2016-01-01

    Full Text Available Strong reduction of new aircraft design period using new technology based on artificial intelligence is the key problem mentioned in forecasts of leading aerospace industry research centers. This article covers the approach to devel- opment of quick aerodynamic design methods based on artificial intelligence neural system. The problem is being solved for the classical scheme of small sized unmanned aircraft vehicle (UAV. The principal parts of the method are the mathe- matical model of layout, layout generator of this type of aircraft is built on aircraft neural networks, automatic selection module for cleaning variety of layouts generated in automatic mode, robust direct computational fluid dynamics method, aerodynamic characteristics approximators on artificial neural networks.Methods based on artificial neural networks have intermediate position between computational fluid dynamics methods or experiments and simplified engineering approaches. The use of ANN for estimating aerodynamic characteris-tics put limitations on input data. For this task the layout must be presented as a vector with dimension not exceeding sev-eral hundred. Vector components must include all main parameters conventionally used for layouts description and com- pletely replicate the most important aerodynamics and structural properties.The first stage of the work is presented in the paper. Simplified mathematical model of small sized UAV was developed. To estimate the range of geometrical parameters of layouts the review of existing vehicle was done. The result of the work is the algorithm and computer software for generating the layouts based on ANN technolo-gy. 10000 samples were generated and the dataset containig geometrical and aerodynamic characteristics of layoutwas created.

  1. Metastable structures and size effects in small group dynamics.

    Science.gov (United States)

    Lauro Grotto, Rosapia; Guazzini, Andrea; Bagnoli, Franco

    2014-01-01

    In his seminal works on group dynamics Bion defined a specific therapeutic setting allowing psychoanalytic observations on group phenomena. In describing the setting he proposed that the group was where his voice arrived. This physical limit was later made operative by assuming that the natural dimension of a therapeutic group is around 12 people. Bion introduced a theory of the group aspects of the mind in which proto-mental individual states spontaneously evolve into shared psychological states that are characterized by a series of features: (1) they emerge as a consequence of the natural tendency of (both conscious and unconscious) emotions to combine into structured group patterns; (2) they have a certain degree of stability in time; (3) they tend to alternate so that the dissolution of one is rapidly followed by the emergence of another; (4) they can be described in qualitative terms according to the nature of the emotional mix that dominates the state, in structural terms by a kind of typical "leadership" pattern, and in "cognitive" terms by a set of implicit expectations that are helpful in explaining the group behavior (i.e., the group behaves "as if" it was assuming that). Here we adopt a formal approach derived from Socio-physics in order to explore some of the structural and dynamic properties of this small group dynamics. We will described data from an analytic DS model simulating small group interactions of agents endowed with a very simplified emotional and cognitive dynamic in order to assess the following main points: (1) are metastable collective states allowed to emerge in the model and if so, under which conditions in the parameter space? (2) can these states be differentiated in structural terms? (3) to what extent are the emergent dynamic features of the systems dependent of the system size? We will finally discuss possible future applications of the quantitative descriptions of the interaction structure in the small group clinical setting.

  2. Metastable structures and size effects in small group dynamics

    Directory of Open Access Journals (Sweden)

    Rosapia eLauro Grotto

    2014-07-01

    Full Text Available In his seminal works on group dynamics Bion defined a specific therapeutic setting allowing psychoanalytic observations on group phenomena. In describing the setting he proposed that the group was where his voice arrived. This physical limit was later made operative by assuming that the natural dimension of a therapeutic group is around 12 people. Bion introduced a theory of the group aspects of the mind in which proto-mental individual states spontaneously evolve into shared psychological states that are characterized by a series of features: 1 they emerge as a consequence of the natural tendency of (both conscious and unconscious emotions to combine into structured group patterns; 2 they have a certain degree of stability in time; 3 they tend to alternate so that the dissolution of one is rapidly followed by the emergence of another; 4 they can be described in qualitative terms according to the nature of the emotional mix that dominates the state, in structural terms by a kind of typical 'leadership’ pattern, and in 'cognitive’ terms by a set of implicit expectations that are helpful in explaining the group behavior (i.e. the group behaves 'as if’ it was assuming that…. Here we adopt a formal approach derived from Socio-physics in order to explore some of the structural and dynamic properties of this small group dynamics. We will described data from an analytic DS model simulating small group interactions of agents endowed with a very simplified emotional and cognitive dynamic in order to assess the following main points: 1 are metastable collective states allowed to emerge in the model and if so, under which conditions in the parameter space? 3 can these states be differentiated in structural terms? 3 to what extent are the emergent dynamic features of the systems dependent of the system size? We will finally discuss possible future applications of the quantitative descriptions of the interaction structure in the small group clinical

  3. A Novel Technology for Measurements of Dielectric Properties of Extremely Small Volumes of Liquids

    Directory of Open Access Journals (Sweden)

    Wei-Na Liu

    2016-01-01

    Full Text Available A high sensitivity sensor for measurement radio frequency (RF dielectric permittivity of liquids is described. Interference is used and parasitic effects are cancellation, which makes the sensor can catch weak signals caused by liquids with extremely small volumes. In addition, we present the relationship between transmission coefficient and permittivity of liquids under test (LUT. Using this sensor, quantitative measurements of the dielectric properties at 5.8 GHz are demonstrated of LUTs. Experiments show that the proposed method only requires the volume of 160 nanoliters for liquids. Therefore, the technology can be used for RF spectroscopic analysis of biological samples and extremely precious liquids.

  4. 78 FR 51263 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2013-08-20

    ... set aside for small businesses, Small Disabled Veteran Owned Small Business, Women-Owned Small... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  5. The small size telescope projects for the Cherenkov Telescope Array

    CERN Document Server

    ,

    2015-01-01

    The small size telescopes (SSTs), spread over an area of several square km, dominate the CTA sensitivity in the photon energy range from a few TeV to over 100 TeV, enabling for the detailed exploration of the very high energy gamma-ray sky. The proposed telescopes are innovative designs providing a wide field of view. Two of them, the ASTRI (Astrophysics con Specchi a Tecnologia Replicante Italiana) and the GCT (Gamma-ray Cherenkov Telescope) telescopes, are based on dual mirror Schwarzschild-Couder optics, with primary mirror diameters of 4 m. The third, SST-1M, is a Davies-Cotton design with a 4 m diameter mirror. Progress with the construction and testing of prototypes of these telescopes is presented. The SST cameras use silicon photomultipliers, with preamplifier and readout/trigger electronics designed to optimize the performance of these sensors for (atmospheric) Cherenkov light. The status of the camera developments is discussed. The SST sub-array will consist of about 70 telescopes at the CTA souther...

  6. Larger trinucleotide repeat size in the androgen receptor gene of infertile men with extremely severe oligozoospermia.

    Science.gov (United States)

    Patrizio, P; Leonard, D G; Chen, K L; Hernandez-Ayup, S; Trounson, A O

    2001-01-01

    Androgens are significant regulators of human spermatogenesis. Their action is mediated through the androgen receptor (AR), which binds to the androgen responsive element on DNA and regulates gene transcription. Men become infertile with spinobulbar muscular atrophy (Kennedy disease) caused by a trinucleotide repeat expansion, > or = 40 CAG repeats, in the AR gene located on the X chromosome. In this prospective study, we investigated whether the variable size, larger repeats, of this trinucleotide could alter AR function and result in impaired spermatogenesis. A total of 69 infertile men were studied. Clinical and laboratory analysis showed idiopathic, nonobstructive azoospermia in 16 men, extremely severe oligozoospermia in 27 men (PCR) amplification across the AR repeat region. Accurate size determination of the PCR product using an ABI 373 DNA sequencer allowed precise calculation of CAG repeat sizes. The AR gene was not analyzed for other types of mutations. The difference in CAG repeat size between infertile men and proven fertile controls was statistically significant, P = .03. Patients with extremely severe oligozoospermia had significantly longer CAG repeat tracts (mean, 25.4 +/- 4.0; P = .0005; range 20-39) than controls (mean, 22 +/- 2.8; range 12-30) or patients with severe oligozoospermia (mean, 22.2 +/- 2.3; range 18-26). None of the 26 infertile men with sperm counts CAG repeats compared with 6 out of 45 controls (13%; P = .06). This study suggests that some men with severe impairment of spermatogenesis have longer trinucleotide repeats in the AR gene. Although direct evidence is missing, lower affinity between androgen and the AR protein or decreased AR protein availability with longer repeats could be responsible for a diminished androgen effect on spermatogenesis. Two of the patients in the extremely severe oligozoospermia group had 35 and 39 CAG repeats, respectively (normal range is 11 to 33). Although not yet considered a mutation, longer

  7. 77 FR 56755 - Small Business Size Standards; Adoption of 2012 North American Industry Classification System for...

    Science.gov (United States)

    2012-09-14

    ... modifications of the North American Industry Classification System (NAICS) into its table of small business size... RIN 3245-AG47 Small Business Size Standards; Adoption of 2012 North American Industry Classification System for Size Standards; Correction AGENCY: U.S. Small Business Administration. ACTION: Interim...

  8. Pregnant woman with an extremely small uterus due to pelvic irradiation in childhood.

    Science.gov (United States)

    Watanabe, Takashi; Matsubara, Shigeki; Saito, Yutaka; Usui, Rie; Mugishima, Hideo; Suzuki, Mitsuaki

    2012-03-01

    A female cancer survivor, having suffered malignant lymphoma during childhood and received radio- and chemotherapy, became pregnant. Her uterus was extremely small and in the 22nd week of gestation, acute uterine contractions occurred, leading to preterm delivery and resulting in the death of the infant. Pelvic irradiation in childhood was considered to have caused a small uterus and thus brought on preterm delivery. The younger the patient, the more vulnerable the uterus is to irradiation. The exposure dose to the uterus in pediatric cancer patients should therefore be reduced, especially in younger patients. The cooperation of pediatric cancer specialists and obstetricians is necessary to preserve the future fertility of female cancer survivors.

  9. 77 FR 7489 - Small Business Size Standards: Professional, Technical, and Scientific Services

    Science.gov (United States)

    2012-02-10

    ... contracts, retain or regain small business size eligibility for Federal assistance, and successfully perform... entrepreneurship, perform on larger Federal contracts, and retain or regain their small business size status. These... size standard. In the past, SBA gave considerable weight to public comments on the engineering size...

  10. Extreme size and sequence variation in the ITS rDNA of Bremia lactucae.

    Science.gov (United States)

    Choi, Young-Joon; Hong, Seung-Boem; Shin, Hyeon-Dong

    2007-02-01

    Bremia lactucae Regel (Chromista, Peronosporaceae) is an economically destructive pathogen, which causes downy mildew disease on lettuce (Lactuca sativa L.) worldwide. The ribosomal internal transcribed spacer (ITS) of Bremia lactucae isolates was analyzed for the first time. The ITS region of lettuce downy mildew was observed to have a size of 2458 bp; thereby, having one of the longest ITS sizes recorded to date. The majority of the extremely large sized ITS2 length of 2086 was attributed to the additional presences of nine repetitive elements with lengths of 179-194 bp, which between them shared the low homology of 48-69%. Comparison of the ITS2 sequences with the B. lactucae isolates from other host plants showed that isolates present on Lactuca sativa were distinct from those on L. indica var. laciniata, as well as Hemistepta and Youngia. We suggest the high degree of sequence heterogeneity exhibited in the ITS2 region of B. lactucae may warrant the specific detection and diagnosis of this destructive pathogen or its division into several distinct species.

  11. Application of Nanometer-Size Titanium Dioxide in Extreme-Trace V(Ⅴ) Analysis

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    The adsorption properties of nanometer-size TiO2 for V(Ⅴ) were studied. The adsorption rate could reach above 99% when the pH values were at the range of 4-10. The adsorption balance time was 10 min , the saturation capacity of adsorption of nanometer-size TiO2 to V(Ⅴ) was 6.43 mg per gram. Using 2 mL 1.5 mol·L-1 NaOH as elution, we found the elution rate could reach 95%. A novel method of extreme-trace V(Ⅴ) preconcentration with nanometer-size titanium dioxide and determination by graphite furnace atomic absorption spectroscopy (GFAAS) was advanced. The detection limit(3σ)of the method was 0.61 μg·L-1, and the relative standard deviation was 8.1% (n=6) of 2.5 μg·L-1 V(Ⅴ). Environmental samples experiments were also conducted to test the feasibility of the method, and it came out that the recovery rates were between 91.2% and 102.0%.

  12. Small Scale Yielding Correction of Constraint Loss in Small Sized Fracture Toughness Test Specimens

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Maan Won; Kim, Min Chul; Lee, Bong Sang; Hong, Jun Hwa [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    2005-07-01

    Fracture toughness data in the ductile-brittle transition region of ferritic steels show scatter produced by local sampling effects and specimen geometry dependence which results from relaxation in crack tip constraint. The ASTM E1921 provides a standard test method to define the median toughness temperature curve, so called Master Curve, for the material corresponding to a 1T crack front length and also defines a reference temperature, T{sub 0}, at which median toughness value is 100 MPam for a 1T size specimen. The ASTM E1921 procedures assume that high constraint, small scaling yielding (SSY) conditions prevail at fracture along the crack front. Violation of the SSY assumption occurs most often during tests of smaller specimens. Constraint loss in such cases leads to higher toughness values and thus lower T{sub 0} values. When applied to a structure with low constraint geometry, the standard fracture toughness estimates may lead to strongly over-conservative estimates. A lot of efforts have been made to adjust the constraint effect. In this work, we applied a small-scale yielding correction (SSYC) to adjust the constraint loss of 1/3PCVN and PCVN specimens which are relatively smaller than 1T size specimen at the fracture toughness Master Curve test.

  13. Renormalization-group theory for finite-size scaling in extreme statistics.

    Science.gov (United States)

    Györgyi, G; Moloney, N R; Ozogány, K; Rácz, Z; Droz, M

    2010-04-01

    We present a renormalization-group (RG) approach to explain universal features of extreme statistics applied here to independent identically distributed variables. The outlines of the theory have been described in a previous paper, the main result being that finite-size shape corrections to the limit distribution can be obtained from a linearization of the RG transformation near a fixed point, leading to the computation of stable perturbations as eigenfunctions. Here we show details of the RG theory which exhibit remarkable similarities to the RG known in statistical physics. Besides the fixed points explaining universality, and the least stable eigendirections accounting for convergence rates and shape corrections, the similarities include marginally stable perturbations which turn out to be generic for the Fisher-Tippett-Gumbel class. Distribution functions containing unstable perturbations are also considered. We find that, after a transitory divergence, they return to the universal fixed line at the same or at a different point depending on the type of perturbation.

  14. Influence of Lower Extremity Muscle Size and Quality on Stair-Climb Performance in Career Firefighters.

    Science.gov (United States)

    Kleinberg, Craig R; Ryan, Eric D; Tweedell, Andrew J; Barnette, Timothy J; Wagoner, Chad W

    2016-06-01

    The purpose of this study was to examine the influence of lower extremity muscular size and quality on stair-climb performance (SCP) in career firefighters. Forty-six male career firefighters (age = 37.0 ± 7.2 years; stature = 180.2 ± 6.9 cm; body mass = 108.0 ± 19.8 kg) volunteered for this study. Panoramic ultrasound images of the vastus lateralis and rectus femoris were obtained to determine cross-sectional area (CSA) and echo intensity (EI) of each muscle. The CSA of each muscle was then summed together and normalized to body mass (CSA/BM [QCSA]). Additionally, EI was averaged across both muscles (QEI). Participants then performed a timed and weighted SCP assessment where they ascended and descended 26 stairs 4 times as quickly as possible while wearing a weighted vest (22.73 kg) to simulate the weight of their self-contained breathing apparatus and turnout gear. Bivariate correlations and stepwise regression analyses were used to examine the relationships among variables and the relative contributions of QCSA and QEI to SCP. Partial correlations were used to examine the relationship between QCSA and SCP and QEI and SCP while controlling for age and body mass index (BMI). The results indicated that QCSA and QEI were significantly related to SCP before (r = -0.492, p = 0.001; r = 0.363, p = 0.013, respectively) and after accounting for age and BMI (r = -0.324, p = 0.032; r = 0.413, p = 0.005, respectively). Both QCSA and QEI contributed significantly to the prediction of SCP (r = 0.560, p < 0.001). These findings indicate that lower extremity muscle size and quality are important contributors to critical firefighting tasks, which have been shown to be improved with resistance training.

  15. Implications of extreme sexual size dimorphism for thermoregulation in a freshwater turtle.

    Science.gov (United States)

    Bulté, Grégory; Blouin-Demers, Gabriel

    2010-02-01

    Sexual size dimorphism (SSD) is a common phenomenon in animals. In many species females are substantially larger than males. Because body size plays a central role in modulating the body temperature (T (b)) of ectotherms, intersexual differences in body size may lead to important intersexual differences in thermoregulation. In addition, because SSD is realized by differences in growth rate and because growth rate is strongly temperature dependent in ectotherms, a conflict between male reproductive behaviour and thermoregulation may affect the expression of SSD. In this study, we investigated the thermal implications of SSD in a reptile exhibiting spectacular female-biased SSD: the northern map turtle (Graptemys geographica). Over three seasons, we collected >150,000 measurements of T (b) in free-ranging adult and juvenile northern map turtles using surgically implanted miniature temperature loggers. Northern map turtles exhibited seasonal patterns of thermoregulation typical of reptiles in northern latitudes, but we found that large adult females experienced a lower daily maximum T (b) and a narrower daily range of T (b) than adult males and small juvenile females. In addition, despite more time spent basking, large adult females were not able to thermoregulate as accurately as small turtles. Our findings strongly suggest that body size limits the ability to thermoregulate accurately in large females. By comparing thermoregulatory patterns between adult males and juvenile females of similar body size, we found no evidence that male reproductive behaviours are an impediment to thermoregulation. We also quantified the thermal significance of basking behaviour. We found, contrary to previous findings, that aerial basking allows northern map turtles to raise their T (b) substantially above water temperature, indicating that basking behaviour likely plays an important role in thermoregulation.

  16. Limitations of mRNA amplification from small-size cell samples

    Directory of Open Access Journals (Sweden)

    Myklebost Ola

    2005-10-01

    Full Text Available Abstract Background Global mRNA amplification has become a widely used approach to obtain gene expression profiles from limited material. An important concern is the reliable reflection of the starting material in the results obtained. This is especially important with extremely low quantities of input RNA where stochastic effects due to template dilution may be present. This aspect remains under-documented in the literature, as quantitative measures of data reliability are most often lacking. To address this issue, we examined the sensitivity levels of each transcript in 3 different cell sample sizes. ANOVA analysis was used to estimate the overall effects of reduced input RNA in our experimental design. In order to estimate the validity of decreasing sample sizes, we examined the sensitivity levels of each transcript by applying a novel model-based method, TransCount. Results From expression data, TransCount provided estimates of absolute transcript concentrations in each examined sample. The results from TransCount were used to calculate the Pearson correlation coefficient between transcript concentrations for different sample sizes. The correlations were clearly transcript copy number dependent. A critical level was observed where stochastic fluctuations became significant. The analysis allowed us to pinpoint the gene specific number of transcript templates that defined the limit of reliability with respect to number of cells from that particular source. In the sample amplifying from 1000 cells, transcripts expressed with at least 121 transcripts/cell were statistically reliable and for 250 cells, the limit was 1806 transcripts/cell. Above these thresholds, correlation between our data sets was at acceptable values for reliable interpretation. Conclusion These results imply that the reliability of any amplification experiment must be validated empirically to justify that any gene exists in sufficient quantity in the input material. This

  17. 78 FR 77343 - Small Business Size Standards: Utilities

    Science.gov (United States)

    2013-12-23

    ... years, SBA has received comments that its size standards have not kept up with changes in the economy... environment; whether SBA's applications of anchor size standards are appropriate in the current economy... was based on NAICS 2007. In the NAICS 2012 updates, considering the recent growth of renewable...

  18. 75 FR 61591 - Small Business Size Standards; Other Services.

    Science.gov (United States)

    2010-10-06

    ... four Sector 54 industries and NAICS 811212 have shared a $25 million size standard since SBA last..., establish certain minimum or maximum values for size standards. One commenter suggested that there should be....0 35.5 813211--Grantmaking Foundations......... 7.0 30.0 813212--Voluntary Health Organizations.....

  19. 78 FR 77334 - Small Business Size Standards: Construction

    Science.gov (United States)

    2013-12-23

    ..., representative of the value of a company's entire portfolio of completed work in a given period of time, is a... industry groups to obtain their feedback on its methodology and other size standards issues. In addition... and feedback on the size standards review. Moreover, SBA presented the same information to...

  20. Optical characterization of nano-sized organic carbon particles emitted from a small gasoline engine

    Institute of Scientific and Technical Information of China (English)

    Bireswar Paul; Amitava Datta; Aparna Datta; Abhijit Saha

    2013-01-01

    The nano-sized organic carbon (NOC) particles emitted from a small gasoline engine were characterized using various ex situ optical techniques to assess their hazardous impact.The exhaust gas was sampled iso-kinetically by a quartz probe and passed through de-ionized water to gather the hydrophilic carbonaceous particulates as hydrosol.The hydrodynamic diameter of the particles ranged between 1.7 and 3.6 nm at no load,with a mean diameter of 2.4 nm.The particle size in the engine exhaust was found to increase at higher loads,which is attributed to coagulation of the particles.The chemical structure of the particles was analyzed using UV-vis and infra-red spectroscopy.Both the band gap energy and oscillator strength data evaluated from the UV-vis absorbance showed that the NOC particles contained polyaromatic hydrocarbon structures with three to five aromatic rings.Infra-red spectroscopy analysis further confirmed the presence of aliphatic and carbonyl functionalities in the aromatic structures of the particles.The fine size of the particles,their high number concentration for the type of the engine under study and their structural features,make the particles extremely hazardous for environment and health.

  1. How Small Is Big: Sample Size and Skewness.

    Science.gov (United States)

    Piovesana, Adina; Senior, Graeme

    2016-09-21

    Sample sizes of 50 have been cited as sufficient to obtain stable means and standard deviations in normative test data. The influence of skewness on this minimum number, however, has not been evaluated. Normative test data with varying levels of skewness were compiled for 12 measures from 7 tests collected as part of ongoing normative studies in Brisbane, Australia. Means and standard deviations were computed from sample sizes of 10 to 100 drawn with replacement from larger samples of 272 to 973 cases. The minimum sample size was determined by the number at which both mean and standard deviation estimates remained within the 90% confidence intervals surrounding the population estimates. Sample sizes of greater than 85 were found to generate stable means and standard deviations regardless of the level of skewness, with smaller samples required in skewed distributions. A formula was derived to compute recommended sample size at differing levels of skewness.

  2. Small-sample likelihood inference in extreme-value regression models

    CERN Document Server

    Ferrari, Silvia L P

    2012-01-01

    We deal with a general class of extreme-value regression models introduced by Barreto- Souza and Vasconcellos (2011). Our goal is to derive an adjusted likelihood ratio statistic that is approximately distributed as \\c{hi}2 with a high degree of accuracy. Although the adjusted statistic requires more computational effort than its unadjusted counterpart, it is shown that the adjustment term has a simple compact form that can be easily implemented in standard statistical software. Further, we compare the finite sample performance of the three classical tests (likelihood ratio, Wald, and score), the gradient test that has been recently proposed by Terrell (2002), and the adjusted likelihood ratio test obtained in this paper. Our simulations favor the latter. Applications of our results are presented. Key words: Extreme-value regression; Gradient test; Gumbel distribution; Likelihood ratio test; Nonlinear models; Score test; Small-sample adjustments; Wald test.

  3. Spatial patterns of sediment dynamics within a medium-sized watershed over an extreme storm event

    Science.gov (United States)

    Gao, Peng; Zhang, Zhirou

    2016-08-01

    In this study, we quantified spatial patterns of sediment dynamics in a watershed of 311 km2 over an extreme storm event using watershed modeling and statistical analyses. First, we calibrated a watershed model, Dynamic Watershed Simulation Model (DWSM) by comparing the predicted with calculated hydrograph and sedigraph at the outlet for this event. Then we predicted values of event runoff volume (V), peak flow (Qpeak), and two types of event sediment yields for lumped morphological units that contain 42 overland elements and 21 channel segments within the study watershed. Two overland elements and the connected channel segment form a first-order subwatershed, several of which constitute a larger nested subwatershed. Next we examined (i) the relationships between these variables and area (A), precipitation (P), mean slope (S), soil erodibility factor, and percent of crop and pasture lands for all overland elements (i.e., the small spatial scale, SSS), and (ii) those between sediment yield, Qpeak, A, P, and event runoff depth (h) for the first-order and nested subwatersheds along two main creeks of the study watershed (i.e., the larger spatial scales, LSS). We found that at the SSS, sediment yield was nonlinearly well related to A and P, but not Qpeak and h; whereas at the LSS, linear relationships between sediment yield and Qpeak existed, so did the Qpeak-A, and Qpeak-P relationships. This linearity suggests the increased connectivity from the SSS to LSS, which was caused by ignorance of channel processes within overland elements. It also implies that sediment was transported at capacity during the extreme event. So controlling sediment supply from the most erodible overland elements may not efficiently reduce the downstream sediment load.

  4. Theoretical Investigation of Trust in Small and Medium Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Valentinas Navickas

    2014-06-01

    Full Text Available The hectic pace of competition pushes the sector of small and medium enterprise to adopt sophisticated marketing ideas. In this context, customers are becoming more and more selective. However, expansion possibilities are burdened by the great variety of limitations. The current study paper aims to investigate the academic perception of trust which is treated as competitive advantage for small and medium enterprises. The object of the article is trust in small and medium enterprises. It has three objectives: to analyse small and medium enterprise characteristics through the academic perspective; to consider trust from the theoretical point of view; and to present the models that centre their attention on the trust as a construct that enhances customer satisfaction. Regarding the novelty of the current study, it brings a novel approach on a great variety of collected understandings of trust and puts an important foundation for future theory and practice investigations.

  5. Temporal changes in allele frequencies in a small marble trout Salmo marmoratus population threatened by extreme flood events.

    Science.gov (United States)

    Pujolar, J M; Vincenzi, S; Zane, L; Crivelli, A J

    2016-03-01

    The effect of extreme floods on the genetic composition of marble trout Salmo marmoratus living in Lipovscek, a tributary of the Soca River in Slovenia, which has been affected by multiple destructive flood events for centuries was investigated. By monitoring genetic variability during the period 2004-2011, apparent signatures of genetic erosion including a decline in observed and expected heterozygosities and allelic richness were observed. Contemporary effective population size was estimated between 11 and 55 individuals, which is congruent with census data. The data suggest asymmetric gene flow between the two sections of the river. The existence of substantial downstream migration (15-19%) was confirmed by paternity analysis. A small (1-3%) upstream migration was also suggested, which was confirmed by tagging data. Overall, low genetic diversity has not prevented the survival of the Lipovscek population, which might be a common feature of salmonid freshwater populations.

  6. 76 FR 63509 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

    Science.gov (United States)

    2011-10-12

    ... 121 RIN 3245-AG27 Small Business Size Standards: Administrative and Support, Waste Management and... Small Business Administration 13 CFR Part 121 Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services; Proposed Rule #0;#0;Federal Register / Vol. 76 , No....

  7. Size multipartite Ramsey numbers for small paths versus books

    Directory of Open Access Journals (Sweden)

    Chula J. Jayawardene

    2016-10-01

    Full Text Available Given $j \\ge 2$,  for  graphs $G$ and $H$, the size Ramsey multipartite number $m_j(G, H$ is defined as the smallest natural number $t$ such that any blue red coloring of the edges of the  graph $K_{j \\times t}$, necessarily containes a red $G$ or a blue $H$ as subgraphs. Let the book with $n$ pages is defined as the graph $K_1 + K_{1,n}$ and denoted by $B_n$. In this paper, we  obtain the exact values of the size Ramsey numbers $m_j(P_3, H$ for $j \\ge 3$ where  $H$ is a book $B_n$. We also derive some upper and lower bounds for the size Ramsey numbers $m_j(P_4, H$ where  $H$ is a book $B_n$.

  8. 76 FR 63216 - Small Business Size Standards: Information

    Science.gov (United States)

    2011-10-12

    ... employees as the size standard for all industries in the Wholesale Trade Sector for SBA financial assistance... based on commissions (such as real estate brokers and travel agents), $5 million include those... for 15 industries in North American Industry Classification System (NAICS) Sector 51, Information. As...

  9. 77 FR 72702 - Small Business Size Standards: Information

    Science.gov (United States)

    2012-12-06

    .... Technological changes, productivity growth, international competition, mergers and acquisitions and updated....103). The fourth issue the commenter raised related to mergers and acquisitions (M&A) activities. The... considered small. SBA disagrees with this comment. Mergers create affiliation (see 13 CFR 121.103) between or...

  10. 76 FR 62313 - Small Business Size and Status Integrity

    Science.gov (United States)

    2011-10-07

    ... Federal electronic database for the purpose of being considered for award of a Federal grant, contract... award to a small business concern. (3) Registration on any Federal electronic database for the purpose.... (3) Registration on any Federal electronic database for the purpose of being considered for award...

  11. Silent, indirect strategic processes in small and medium sized enterprises

    DEFF Research Database (Denmark)

    Larsen, Mette Vinther; Madsen, Charlotte Øland; Rasmussen, Jørgen Gulddahl

    Based on empirical data we in this paper explore day-to-day strategising with an emphasis on phronesis. This way we shed some light on the nearly silent, quiet, indirect strategic change processes as they are practiced and reflected upon by leaders in small companies in their daily practice...

  12. Does Market Size Structure Affect Competition? The Case of Small Business Lending

    OpenAIRE

    Allen N. Berger; Richard J. Rosen; Udell, Gregory F.

    2005-01-01

    Market size structure refers to the distribution of shares of different size classes of local market participants, where the sizes are inclusive of assets both within and outside the local market. We apply this new measure of market structure in two empirical analyses of the U.S. banking industry to address concerns regarding the effects of the consolidation in banking. Our quantity analysis of the likelihood that small businesses borrow from large versus small banks and our small business lo...

  13. 77 FR 72766 - Small Business Size Standards: Support Activities for Mining

    Science.gov (United States)

    2012-12-06

    ... business assistance, SBA establishes small business size definitions (referred to as size standards) for... inflation on its size standards and makes necessary adjustments to its monetary based size standards. SBA's... conditions, its mission and program objectives, the Administration's current policies, suggestions from...

  14. Management of small and medium size enterprises as a carrier of economic growth

    Directory of Open Access Journals (Sweden)

    Ožegović Lazar

    2012-01-01

    Full Text Available Numerous studies in the world of market economy show that the share of small and medium size enterprises is constantly increasing compared to large enterprises. This does not decrease the significance of large enterprises, but the dependence between them gets larger every day. National economies which manage to find the optimal combination between small, medium size and large enterprises are more successful than the others. Management of small and medium size enterprises (SMEs in conceptual terms is similar to the process of management of large enterprises. An organization must be managed in order to function and this rule applies to small and medium size enterprises.

  15. 76 FR 42157 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2011-07-18

    ... businesses, Participants in SBA's 8(a) Business Development (BD) Program, or Women-Owned Small Business (WOSB... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  16. 78 FR 76886 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2013-12-19

    ...) Business Development (BD) Program, or Women-Owned Small Business (WOSB) concerns. DATES: Effective Date... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  17. 76 FR 32257 - Small Business Size Standards; Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2011-06-03

    ..., women-owned small businesses, or Participants in the SBA's 8(a) BD Program provide the product of a... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards; Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  18. 78 FR 42817 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2013-07-17

    ..., Women- Owned Small Businesses, or Participants in SBA's 8(a) Business Development Program provide the... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  19. 75 FR 68394 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-11-05

    ... (BD) Program, or Women-Owned Small Business (WOSB) concerns. DATES: This waiver is effective November... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  20. 76 FR 42157 - Small Business Size Standards; Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2011-07-18

    ...-Owned (SDVO) small businesses, Participants in SBA's 8(a) Business Development (BD) Program, or Women... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards; Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  1. 76 FR 27372 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2011-05-11

    ...) Business Development (BD) Program, or Women-Owned Small Business (WOSB) concerns. DATES: This waiver is... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  2. 75 FR 28077 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-05-19

    ... ``class of products'' for which there are no small business manufacturers or processors available to... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  3. 75 FR 38156 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-07-01

    .... SUMMARY: The U.S. Small Business Administration (SBA) is considering granting a class waiver of the... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  4. 75 FR 47036 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-08-04

    ...-Portable). SUMMARY: The U.S. Small Business Administration (SBA) is granting a class waiver of the... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  5. 75 FR 40857 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-07-14

    ... sources of small business manufacturers of this class of products. No comments were received in response... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION Small Business Size Standards: Waiver of the Nonmanufacturer Rule AGENCY: U.S. Small...

  6. Effects of sample size on estimation of rainfall extremes at high temperatures

    Directory of Open Access Journals (Sweden)

    B. Boessenkool

    2017-09-01

    Full Text Available High precipitation quantiles tend to rise with temperature, following the so-called Clausius–Clapeyron (CC scaling. It is often reported that the CC-scaling relation breaks down and even reverts for very high temperatures. In our study, we investigate this reversal using observational climate data from 142 stations across Germany. One of the suggested meteorological explanations for the breakdown is limited moisture supply. Here we argue that, instead, it could simply originate from undersampling. As rainfall frequency generally decreases with higher temperatures, rainfall intensities as dictated by CC scaling are less likely to be recorded than for moderate temperatures. Empirical quantiles are conventionally estimated from order statistics via various forms of plotting position formulas. They have in common that their largest representable return period is given by the sample size. In small samples, high quantiles are underestimated accordingly. The small-sample effect is weaker, or disappears completely, when using parametric quantile estimates from a generalized Pareto distribution (GPD fitted with L moments. For those, we obtain quantiles of rainfall intensities that continue to rise with temperature.

  7. Research Note: Networking Among Small and Medium-sized Enterprises

    DEFF Research Database (Denmark)

    Limborg, Hans Jørgen; Grøn, Sisse; Flensborg Jensen, Maya

    2014-01-01

    Researchers and regulatory bodies lack an in-depth understanding of how small and mediumsized enterprises (SMEs) make decisions about workplace health and safety improvements and the role played by business networks in these decisions. To improve regulation and support there is a need to understand...... differences between external and internal mechanisms driving SME workplace safety decisions within each network were found: External - pressures from labour inspectors (D - active, B - limited), professional support (D - active, B - partly); Internal - horizontal relations/shared identity (D - very active, B...... that both external pressures and internal motivations must be present to drive SMEs within a network to improve health and safety conditions....

  8. Reducing Size, Weight, and Power (SWaP) of Perception Systems in Small Autonomous Aerial Systems

    Science.gov (United States)

    Jones, Kennie H.; Gross, Jason

    2014-01-01

    The objectives are to examine recent trends in the reduction of size, weight, and power (SWaP) requirements of sensor systems for environmental perception and to explore new technology that may overcome limitations in current systems. Improving perception systems to facilitate situation awareness is critical in the move to introduce increasing autonomy in aerial systems. Whether the autonomy is in the current state-of-the-art of increasing automation or is enabling cognitive decisions that facilitate adaptive behavior, collection of environmental information and fusion of that information into knowledge that can direct actuation is imperative to decisions resulting in appropriate behavior. Artificial sensory systems such as cameras, radar, LIDAR, and acoustic sensors have been in use on aircraft for many years but, due to the large size and weight of the airplane and electrical power made available through powerful engines, the SWaP requirements of these sensors was inconsequential. With the proliferation of Remote Piloted Vehicles (RPV), the trend is in significant reduction in SWaP of the vehicles. This requires at least an equivalent reduction in SWaP for the sensory systems. A survey of some currently available sensor systems and changing technology will reveal the trend toward reduction of SWaP of these systems and will predict future reductions. A new technology will be introduced that provides an example of a desirable new trend. A new device replaces multiple conventional sensory devices facilitating synchronization, localization, altimetry, collision avoidance, terrain mapping, and data communication in a single integrated, small form-factor, extremely lightweight, and low power device that it is practical for integration into small autonomous vehicles and can facilitate cooperative behavior. The technology is based on Ultra WideBand (UWB) radio using short pulses of energy rather than continuous sine waves. The characteristics of UWB yield several

  9. Spontaneous formation of small sized albumin/acacia coacervate particles.

    Science.gov (United States)

    Burgess, D J; Singh, O N

    1993-07-01

    Microgel coacervate particles form spontaneously on mixing aqueous solutions of oppositely charged albumin and acacia, under specific conditions of pH, ionic strength, and polyion concentration, close to but not at the optimum conditions for maximum coacervate yield. The mean particle diameter of these coacervate particles is approximately 6 microns when suspended in aqueous media, as determined by HIAC/Royco particle analysis. The geometric standard deviation of the particles falls in the range 1.2-1.9 microns. The particle size was not dependent on the method of emulsification of the coacervate in the equilibrium phase, or on the stirring speed applied during the manufacturing process. The microgel particles were stable on storage, for periods up to forty-six days, without the addition of a chemical cross-linking agent, or the application of heat. Stability was measured with respect to the change in particle size of samples stored at different temperatures. The non-cross-linked microcapsules were also shown to be stable on pH change, to pH values outside the coacervation pH range. At the optimum conditions for maximum coacervate yield the albumin/acacia system formed a very viscous coacervate phase, which was unsuitable for microcapsule preparation. The rheological properties of albumin/acacia and gelatin/acacia complex coacervates optimized for maximum coacervate yield were compared. The albumin/acacia coacervate was shown to be three orders of magnitude more viscous than the gelatin/acacia system.

  10. Sizing aspects of a small scale grid connected PV system

    Energy Technology Data Exchange (ETDEWEB)

    Bartha, S.; Teodoreanu, D.I.; Teodoreanu, M.; Negreanu, C. [I.C.P.E.-New Energy Sources Laboratory (NESL), Bucharest (Romania); Farkas, I.; Seres, I. [Szent Istvan University, Goedoelloe (Hungary). Department of Physics and Process Control

    2008-07-01

    Photovoltaics can be used in grid connected mode in two ways: as array installed at the end use site, such as on rooftops, or as utility-scale generating stations. The present paper describes a small-scale grid connected Photovoltaic system. The paper starts with the structure and characterization of the system. The principal technical parameter data are also presented. The used monitoring parameters indicate the principal meteorological data, air temperature and solar radiation data for the location sited at Agigea, at the Black Sea and the produced energy by the PV modules. The present application is made by 1 subsystem with 1200 Wp power and with the panel inclination possibility, using different type of PV modules. The paper presents a simulation model for this system realized with commercial software packages and with a one self made Matlab model that evaluates the energy balance of the PV system. All the simulation and measurements data are presented. (orig.)

  11. Progressive prediction method for failure data with small sample size

    Institute of Scientific and Technical Information of China (English)

    WANG Zhi-hua; FU Hui-min; LIU Cheng-rui

    2011-01-01

    The small sample prediction problem which commonly exists in reliability analysis was discussed with the progressive prediction method in this paper.The modeling and estimation procedure,as well as the forecast and confidence limits formula of the progressive auto regressive(PAR) method were discussed in great detail.PAR model not only inherits the simple linear features of auto regressive(AR) model,but also has applicability for nonlinear systems.An application was illustrated for predicting the future fatigue failure for Tantalum electrolytic capacitors.Forecasting results of PAR model were compared with auto regressive moving average(ARMA) model,and it can be seen that the PAR method can be considered good and shows a promise for future applications.

  12. 77 FR 55755 - Small Business Size Standards: Agriculture, Forestry, Fishing, and Hunting

    Science.gov (United States)

    2012-09-11

    ... Federal small business assistance, SBA establishes small business size definitions (referred to as size... industries in response to requests from the public and Federal agencies. SBA also adjusts all monetary based..., its mission and program objectives, the Administration's current policies, suggestions from industry...

  13. Managers' Understanding of Workplace Health Promotion within Small and Medium-Sized Enterprises: A Phenomenological Study

    Science.gov (United States)

    Moore, Ann; Parahoo, Kader; Fleming, Paul

    2011-01-01

    Objective: This study aimed at exploring managers' understanding of workplace health promotion and experiences of workplace health promotion activity within small and medium-sized enterprises. Design: A Heideggerian interpretive phenomenological methodology was adopted. Setting: This study was undertaken with small and medium-sized enterprise…

  14. Managers' Understanding of Workplace Health Promotion within Small and Medium-Sized Enterprises: A Phenomenological Study

    Science.gov (United States)

    Moore, Ann; Parahoo, Kader; Fleming, Paul

    2011-01-01

    Objective: This study aimed at exploring managers' understanding of workplace health promotion and experiences of workplace health promotion activity within small and medium-sized enterprises. Design: A Heideggerian interpretive phenomenological methodology was adopted. Setting: This study was undertaken with small and medium-sized enterprise…

  15. Design and implementation of web server soft load balancing in small and medium-sized enterprise

    Science.gov (United States)

    Yan, Liu

    2011-12-01

    With the expansion of business scale, small and medium-sized enterprises began to use information platform to improve their management and competition ability, the server becomes the core factor which restricts the enterprise's infomationization construction. This paper puts forward a suitable design scheme for small and medium-sized enterprise web server soft load balancing, and proved it effective through experiment.

  16. 77 FR 30265 - Submission for OMB Review; Small Business Size Representation

    Science.gov (United States)

    2012-05-22

    ...; Small Business Size Representation AGENCY: Department of Defense (DOD), General Services Administration... representation. A notice was published in the Federal Register at 77 FR 13329, on March 6, 2012. No comments were... Information Collection 9000- 0163, Small Business Size Representation, by any of the following methods...

  17. 76 FR 27952 - Small Business Size Standards: Professional, Scientific and Technical Services.

    Science.gov (United States)

    2011-05-13

    ... ADMINISTRATION 13 CFR Part 121 RIN 3245-AG07 Small Business Size Standards: Professional, Scientific and...) proposed to increase small business size standards for 35 industries and one sub-industry in North American Industry Classification System (NAICS) Sector 54, Professional, Scientific and Technical Services and...

  18. An Extremely Rare Case of Advanced Metastatic Small Cell Neuroendocrine Carcinoma of Sinonasal Tract

    Directory of Open Access Journals (Sweden)

    Yu Yu Thar

    2016-01-01

    Full Text Available Small cell neuroendocrine carcinoma (SNEC is a rare form of malignancy. It mainly presents as bronchogenic neoplasm, and the extrapulmonary form accounts for only 0.1% to 0.4% of all cancers. These extrapulmonary tumors have been described most frequently in the urinary bladder, prostate, esophagus, stomach, colon and rectum, gall bladder, head and neck, cervix, and skin. Primary SNEC of the sinonasal tract is extremely rare with only less than 100 cases reported in the literature. Because of extreme rarity and aggressiveness of the tumor, the management for this entity varies considerably mandating multimodality approach. In this paper, we report a patient presented with left-sided facial swelling, and the histopathologic examination confirmed primary SNEC of left sinonasal tract. The tumor involved multiple paranasal sinuses with invasion into the left orbit and left infratemporal fossa and metastasized to cervical lymph nodes and bone. The patient encountered devastating outcome in spite of optimal medical management and treatment with palliative chemotherapy highlighting the necessity for further research of primary SNEC of head and neck.

  19. Thermoeconomic optimization of small size central air conditioner

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, G.Q.; Wang, L.; Liu, L.; Wang, Z. [Hunan University (China). College of Civil Engineering

    2004-03-01

    The application of thermoeconomic optimization design in an air-conditioning system is important in achieving economical life cycle cost. Previous work on thermoeconomic optimization mainly focused on directly calculating exergy input into the system. However, it is usually difficult to do so because of the uncertainty of input power of fan on the air side of the heat-exchanger and that of pump in the system. This paper introduces a new concept that exergy input into the system can be substituted for the sum of exergy destruction and exergy output from the system according to conservation of exergy. Although it is also difficult for a large-scale system to calculate exergy destruction, it is feasible to do so for a small-scale system, for instance, villa air conditioner (VAC). In order to perform thermoeconomic optimization, a program is firstly developed to evaluate the thermodynamic property of HFC 134a on the basis of Martin-Hou state equation. Authors develop thermodynamic and thermoeconomic objective functions based on second law and thermoeconomic analysis of VAC system. Two optimization results are obtained. The design of VAC only aimed at decreasing the energy consumption is not comprehensive. Life cycle cost at thermoeconomic optimization is lower than that at thermodynamic optimization. (author)

  20. Digital marketing in relation to business factors in small and mid-sized companies in Finland

    OpenAIRE

    Schelling, Axel

    2014-01-01

    This research takes look at how small and mid-sized companies in Finland use digital me-dia resources to promote their business and products. It investigates the use of different marketing methods and how those businesses make use the available tools with regards to the company size, annual revenue and other significant parameter. Since small and mid-sized companies have the some of the greatest problems to represent themselves online because of limited resources, it is therefore the idea for...

  1. 76 FR 70680 - Small Business Size Standards: Real Estate and Rental and Leasing

    Science.gov (United States)

    2011-11-15

    ... ADMINISTRATION 13 CFR Part 121 RIN 3245-AG28 Small Business Size Standards: Real Estate and Rental and Leasing... Leasing. As part of its ongoing comprehensive review of all size standards, SBA has evaluated all size... industry and Federal contracting factors for ``Leasing of Building Space to Federal Government by...

  2. Comparing Server Energy Use and Efficiency Using Small Sample Sizes

    Energy Technology Data Exchange (ETDEWEB)

    Coles, Henry C.; Qin, Yong; Price, Phillip N.

    2014-11-01

    This report documents a demonstration that compared the energy consumption and efficiency of a limited sample size of server-type IT equipment from different manufacturers by measuring power at the server power supply power cords. The results are specific to the equipment and methods used. However, it is hoped that those responsible for IT equipment selection can used the methods described to choose models that optimize energy use efficiency. The demonstration was conducted in a data center at Lawrence Berkeley National Laboratory in Berkeley, California. It was performed with five servers of similar mechanical and electronic specifications; three from Intel and one each from Dell and Supermicro. Server IT equipment is constructed using commodity components, server manufacturer-designed assemblies, and control systems. Server compute efficiency is constrained by the commodity component specifications and integration requirements. The design freedom, outside of the commodity component constraints, provides room for the manufacturer to offer a product with competitive efficiency that meets market needs at a compelling price. A goal of the demonstration was to compare and quantify the server efficiency for three different brands. The efficiency is defined as the average compute rate (computations per unit of time) divided by the average energy consumption rate. The research team used an industry standard benchmark software package to provide a repeatable software load to obtain the compute rate and provide a variety of power consumption levels. Energy use when the servers were in an idle state (not providing computing work) were also measured. At high server compute loads, all brands, using the same key components (processors and memory), had similar results; therefore, from these results, it could not be concluded that one brand is more efficient than the other brands. The test results show that the power consumption variability caused by the key components as a

  3. 75 FR 61604 - Small Business Size Standards; Accommodation and Food Services Industries

    Science.gov (United States)

    2010-10-06

    ... Historically Underutilized Business Zones (HUBZone), women owned small businesses and service disabled veteran... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Part 121 RIN: 3245-AF71 Small Business Size Standards; Accommodation and Food...

  4. 77 FR 72691 - Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services

    Science.gov (United States)

    2012-12-06

    ... From the Federal Register Online via the Government Publishing Office SMALL BUSINESS ADMINISTRATION 13 CFR Part 121 RIN 3245-AG27 Small Business Size Standards: Administrative and Support, Waste Management and Remediation Services AGENCY: U.S. Small Business Administration. ACTION: Final rule....

  5. A ten-year review of lower extremity burns in diabetics: small burns that lead to major problems.

    Science.gov (United States)

    Barsun, Alura; Sen, Soman; Palmieri, Tina L; Greenhalgh, David G

    2013-01-01

    Diabetes mellitus with its resulting neurovascular changes may lead to an increased risk of burns and impaired wound healing. The purpose of this article is to review 10 years of experience with foot and lower leg burns in patients with diabetes at a single adult burn center. Patients with lower extremity burns and diabetes mellitus, between May 1999 and December 2009, were identified in the Trauma Registry of the American College of Surgeons database, and their charts were reviewed for data related to their outcomes. Sixty-eight diabetic patients, 87% male, with a mean age of 54 years, sustained foot or lower extremity burns with 37 having burns resulting from insensate feet. The pathogenesis included walking on a hot or very cold surface (8), soaking feet in hot water (22), warming feet on or near something hot such as a heater (13), or spilling hot water (7). The majority of patients were taking insulin (59.6%) or oral hyperglycemic medications (34.6%). Blood sugar levels were not well controlled (mean glucose, 215.8 mg/dl; mean hemoglobin A1c, 9.08%). Renal disease was common with admission serum blood urea nitrogen (27.5 mg/dl) and creatinine (2.21 mg/dl), and 13 were on dialysis preinjury. Cardiovascular problems were common with 39 (57%) having hypertension or cardiac disease, 3 having peripheral vascular disease, and 9, previous amputations. The mean burn size was 4.2% TBSA (range, 0.5-15%) with 57% being full thickness. Despite the small burn, the mean length of stay was 15.2 days (range, 1-95), with 5.65 days per 1% TBSA. Inability to heal these wounds was evident in 19 patients requiring readmission (one required 10 operative procedures). At least one patient sustained more than one burn. There were 62 complications with 30 episodes of infection (cellulitis, 28; osteomyelitis, 4; deep plantar infections, 2; ruptured Achilles tendon, 1) and 3 deaths. Eleven patients needed amputations (7 below-knee amputations, 4 transmetatarsal amputations, and 20 toe

  6. Development of Small-sized Fluid Control Valve with Self-holding Function Using Permanent Magnet

    Science.gov (United States)

    Akagi, Tetsuya; Dohta, Shujiro; Ueda, Hirofumi

    Recently, force feedback devices in virtual reality and power assisted nursing care systems have received much attention and active research. In such a control system, an actuator and a driving device such as a control valve are mounted on the human body. In this condition, the size and weight of the control valve become serious problems. At the same time, the valve should be operated with lower energy consumption because of using a limited electrical power. The typical electro magnetic solenoid valve drives its spool using a larger solenoid to open the valve. The complex construction of the valve for sealing makes its miniaturization and the fabrication of a low cost valve more difficult. In addition, the solenoid in the valve consumes more electrical power while the valve is kept opening. The purpose of our study is to develop a small-sized, lightweight, lower energy consumption and flexible control valve that can be safe enough to mount on the human body at a lower cost. In our pervious study, we proposed and tested the control valve that can open using a vibration motor. In this study, we propose and test a new type of fluid control valve with a self-holding function. The new valve uses a permanent magnet ball. It has a cylindrical magnet and two solenoids. The self-holding function of the valve is done as follows. When one side of the solenoid is stimulated by the current momentarily, the solenoid gives a repulsive force to the cylindrical magnet. The magnet moves toward the opposite side of the solenoid and is attracted to the iron core. Then, the magnet ball moves toward the cylindrical magnet and opens the orifice. The valve can keep open without electrical energy. As a result, the valve with the extremely lower energy consumption can be developed.

  7. Evaluation research of small and medium-sized enterprise informatization on big data

    Science.gov (United States)

    Yang, Na

    2017-09-01

    Under the background of big data, key construction of small and medium-sized enterprise informationization level was needed, but information construction cost was large, while information cost of inputs can bring benefit to small and medium-sized enterprises. This paper established small and medium-sized enterprise informatization evaluation system from hardware and software security level, information organization level, information technology application and the profit level, and information ability level. The rough set theory was used to brief indexes, and then carry out evaluation by support vector machine (SVM) model. At last, examples were used to verify the theory in order to prove the effectiveness of the method.

  8. Mechanism of Interaction between Entrepreneurial Spirit and Growth of Small and Medium Sized Private Enterprises

    Institute of Scientific and Technical Information of China (English)

    Peng XIE

    2016-01-01

    In the context of government appeal of " mass entrepreneurship and innovation",all areas launched the movement of " mass entrepreneurship" and " grassroots entrepreneurship". As parts of vitality of China’s market economy,small and medium sized private enterprises become grassroots of market competition in talents,funds,and technologies. This paper combined three levels of entrepreneurial spirit and small and medium sized private enterprises,studied acting mechanism of entrepreneurial spirit,discussed competitive power of small and medium sized private enterprises,and recommended that small and medium sized private enterprises should cultivate core competitive power,adapt to external environment,and create external environment support,to realize sound development.

  9. Study on Electronic Commerce Maturity of Small and Medium-sized Agricultural Enterprises

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    This article advances the concept of electronic commerce maturity of small and medium-sized agricultural enterprises,and establishes the indicator system of electronic commerce maturity of small and medium-sized agricultural enterprises.This indicator system includes 4 first-level indicators(infrastructure,transaction process,operation management,and transaction safety),which are divided into 11 second-level indicators(hardware equipment,computer network,e-procurement,logistics distribution,supply chain management,customer relationship management,and payment security).We use analytic hierarchy process(AHP) to determine the weight of indicator at all levels,and establish fuzzy comprehensive evaluation mathematical model of electronic commerce maturity of small and medium-sized agricultural enterprises.Finally,through examples,we verify the rationality and reliability of evaluation method of electronic commerce maturity of small and medium-sized agricultural enterprises combining analytic hierarchy process(AHP) and fuzzy comprehensive evaluation.

  10. Large- and small-size advantages in sneaking behaviour in the dusky frillgoby Bathygobius fuscus

    Science.gov (United States)

    Takegaki, Takeshi; Kaneko, Takashi; Matsumoto, Yukio

    2012-04-01

    Sneaking tactic, a male alternative reproductive tactic involving sperm competition, is generally adopted by small individuals because of its inconspicuousness. However, large size has an advantage when competition occurs between sneakers for fertilization of eggs. Here, we suggest that both large- and small-size advantages of sneaker males are present within the same species. Large sneaker males of the dusky frillgoby Bathygobius fuscus showed a high success rate in intruding into spawning nests because of their advantage in competition among sneaker males in keeping a suitable position to sneak, whereas small sneakers had few chances to sneak. However, small sneaker males were able to stay in the nests longer than large sneaker males when they succeeded in sneak intrusion. This suggests the possibility of an increase in their paternity. The findings of these size-specific behavioural advantages may be important in considering the evolution of size-related reproductive traits.

  11. Contribution of small and medium sized enterprises in development of agribusiness of Serbian Republic

    Directory of Open Access Journals (Sweden)

    Popović Blaženka

    2009-01-01

    Full Text Available The economic development of Serbian republic is more and more connected with development of small and medium sized enterprises, which represent one of the main bases of Serbian economy. The economic potential of agriculture imposes the need of analyzing the condition in area of small and medium sized entrepreneurship which should be the carrier of future development of agribusiness. By ranging and grouping of Serbian republic municipalities (by discrimination and cluster analysis according to level of development of small and medium sized entrepreneurship in agriculture, the clear view is got in current state of regional development of this agricultural sector as the possibilities of future development. By development of small and medium sized enterprises in agriculture it is possible to achieve strategic goals of Serbian republic agro development and for realization of these goals it is necessary to ensure the stable economic ambient, appropriate pre conditions as measures of support which will be stimulating for development of agribusiness.

  12. Plant species with extremely small populations (PSESP in China: A seed and spore biology perspective

    Directory of Open Access Journals (Sweden)

    Ellie Merrett Wade

    2016-10-01

    Full Text Available Approximately one fifth of the world's plants are at risk of extinction. Of these, a significant number exist as populations of few individuals, with limited distribution ranges and under enormous pressure due to habitat destruction. In China, these most-at-risk species are described as ‘plant species with extremely small populations’ (PSESP. Implementing conservation action for such listed species is urgent. Storing seeds is one of the main means of ex situ conservation for flowering plants. Spore storage could provide a simple and economical method for fern ex situ conservation. Seed and spore germination in nature is a critical step in species regeneration and thus in situ conservation. But what is known about the seed and spore biology (storage and germination of at-risk species? We have used China's PSESP (the first group listing as a case study to understand the gaps in knowledge on propagule biology of threatened plant species. We found that whilst germination information is available for 28 species (23% of PSESP, storage characteristics are only known for 8% of PSESP (10 species. Moreover, we estimate that 60% of the listed species may require cryopreservation for long-term storage. We conclude that comparative biology studies are urgently needed on the world's most threatened taxa so that conservation action can progress beyond species listing.

  13. Performance Verification of the Gravity and Extreme Magnetism Small Explorer GEMS X-Ray Polarimeter

    Science.gov (United States)

    Enoto, Teruaki; Black, J. Kevin; Kitaguchi, Takao; Hayato, Asami; Hill, Joanne E.; Jahoda, Keith; Tamagawa, Toru; Kanako, Kenta; Takeuchi, Yoko; Yoshikawa, Akifumi; Kenward, David

    2014-01-01

    olarimetry is a powerful tool for astrophysical observations that has yet to be exploited in the X-ray band. For satellite-borne and sounding rocket experiments, we have developed a photoelectric gas polarimeter to measure X-ray polarization in the 2-10 keV range utilizing a time projection chamber (TPC) and advanced micro-pattern gas electron multiplier (GEM) techniques. We carried out performance verification of a flight equivalent unit (1/4 model) which was planned to be launched on the NASA Gravity and Extreme Magnetism Small Explorer (GEMS) satellite. The test was performed at Brookhaven National Laboratory, National Synchrotron Light Source (NSLS) facility in April 2013. The polarimeter was irradiated with linearly-polarized monochromatic X-rays between 2.3 and 10.0 keV and scanned with a collimated beam at 5 different detector positions. After a systematic investigation of the detector response, a modulation factor greater than or equal to 35% above 4 keV was obtained with the expected polarization angle. At energies below 4 keV where the photoelectron track becomes short, diffusion in the region between the GEM and readout strips leaves an asymmetric photoelectron image. A correction method retrieves an expected modulation angle, and the expected modulation factor, approximately 20% at 2.7 keV. Folding the measured values of modulation through an instrument model gives sensitivity, parameterized by minimum detectable polarization (MDP), nearly identical to that assumed at the preliminary design review (PDR).

  14. Transformational and transactional leadership: does it work in small to medium-sized enterprises?

    OpenAIRE

    Mesu, J.K.

    2013-01-01

    Using a sample of 755 employees who rated 121 supervisors within 50 Dutch small and medium-sized enterprises (SMEs), this dissertation intends to fill in some of the existing gaps in the literature. Firstly, by investigating whether the impact of transformational and transactional leadership extends from large to small and medium-sized companies. Secondly, by studying potential mediating and moderating effects to obtain a better understanding of the mechanisms by which transformational and tr...

  15. The application of the boundary element method in BEM++ to small extreme Chebyshev ice particles and the remote detection of the ice crystal number concentration of small atmospheric ice particles

    Science.gov (United States)

    Baran, Anthony J.; Groth, Samuel P.

    2017-09-01

    The measurement of the shape and size distributions of small atmospheric ice particles (i.e. less than about 100 μm in size) is still an unresolved problem in atmospheric physics. This paper is composed of two parts, each addressing one of these measurements. In the first part, we report on an application of a new open-source electromagnetic boundary element method (BEM) called ;BEM++; to characterise the shape of small ice particles through the simulation of the two-dimensional (2D) light scattering patterns of extreme Chebyshev ice particles. Previous electromagnetic studies of Chebyshev particles have concentrated upon high Chebyshev orders, but with low Chebyshev deformation parameters. Here, we extend such studies by concentrating on the 2D light scattering properties of Chebyshev particles with extreme deformation parameters, up to 0.5, and with Chebyshev orders up to 16, at a size parameter of 15, in a fixed orientation. The results demonstrate the applicability of BEM++ to the study of the electromagnetic scattering properties of extreme particles and the usefulness of measuring the light scattering patterns of particles in 2D to mimic the scattering behaviours of highly irregular particles, such as dendritic atmospheric ice or hazardous biological and/or aerosol particles. In the second part, we demonstrate the potential application of remotely sensed very-high-resolution brightness temperature measurements of optically thin cirrus between wavelengths of about 8.0 and 12.0 μm to resolve the current atmospheric physics issue of determining the number concentration of small ice particles with size less than about 100 μm.

  16. Development of a measuring system for vapor-jet forms of small-sized fuel injectors; Kogata injector funmu keijo sokutei system no kaihatsu

    Energy Technology Data Exchange (ETDEWEB)

    Hibino, H.; Komatsubara, H.; Kawashima, O.; Fujita, A. [Aisan Industry Co. Ltd., Aichi (Japan)

    1997-10-01

    In the small-sized fuel injectors adapted to the United States` exhaust-gas regulation or the like, the vapor jet is extremely atomized and the jet form as one of the performances of the product has become more important than before. Accordingly, we have developed a measuring system in which the vapor jet of the small-sized fuel injector is irradiated with a flat laser light, the sectional form of the jet that is shining due to diffusion is sampled, and the distribution and the form of the sampled sections are determined by the image processing. 2 refs., 15 figs., 4 tabs.

  17. Effects of YORP-induced rotational fission on the small size end of the Main Belt asteroid size distribution

    Science.gov (United States)

    Rossi, Alessandro; Jacobson, S.; Marzari, F.; Scheeres, D.; Davis, D. R.

    2013-10-01

    From the results of a comprehensive asteroid population evolution model, we conclude that the YORP-induced rotational fission hypothesis has strong repercussions for the small size end of the Main Belt asteroid size frequency distribution. These results are consistent with observed asteroid population statistics. The foundation of this model is the asteroid rotation model of Marzari et al. (2011), which incorporates both the YORP effect and collisional evolution. This work adds to that model the rotational fission hypothesis (i.e. when the rotation rate exceeds a critical value, erosion and binary formation occur). The YORP effect timescale for large asteroids with diameters D > ~6 km is longer than the collision timescale in the Main Belt, thus the frequency of large asteroids is determined by a collisional equilibrium (e.g. Bottke 2005), but for small asteroids with diameters D Morbidelli 2009).

  18. Predictors of organisational performance in small and medium-sized professional service firms

    NARCIS (Netherlands)

    Glunk, Ursula; Wilderom, Celeste P.M.

    1998-01-01

    The paper sets out our theoretical and empirical approach to delineating predictors of stakeholder performance in medium-sized computer service firms. It combines a resource-based approach with recent insights from the literature on small and medium-sized firms, professional service, and computer-se

  19. Small-for-Size Liver Transplantation Increases Pulmonary Injury in Rats: Prevention by NIM811

    Directory of Open Access Journals (Sweden)

    Qinlong Liu

    2012-01-01

    Full Text Available Pulmonary complications after liver transplantation (LT often cause mortality. This study investigated whether small-for-size LT increases acute pulmonary injury and whether NIM811 which improves small-for-size liver graft survival attenuates LT-associated lung injury. Rat livers were reduced to 50% of original size, stored in UW-solution with and without NIM811 (5 μM for 6 h, and implanted into recipients of the same or about twice the donor weight, resulting in half-size (HSG and quarter-size grafts (QSG, respectively. Liver injury increased and regeneration was suppressed after QSG transplantation as expected. NIM811 blunted these alterations >75%. Pulmonary histological alterations were minimal at 5–18 h after LT. At 38 h, neutrophils and monocytes/macrophage infiltration, alveolar space exudation, alveolar septal thickening, oxidative/nitrosative protein adduct formation, and alveolar epithelial cell/capillary endothelial apoptosis became overt in the lungs of QSG recipients, but these alterations were mild in full-size and HSG recipients. Liver pretreatment with NIM811 markedly decreased pulmonary injury in QSG recipients. Hepatic TNFα and IL-1β mRNAs and pulmonary ICAM-1 expression were markedly higher after QSG transplantation, which were all decreased by NIM811. Together, dysfunctional small-for-size grafts produce toxic cytokines, leading to lung inflammation and injury. NIM811 decreased toxic cytokine formation, thus attenuating pulmonary injury after small-for-size LT.

  20. Use of large bulls to improve the body weight of local small sized buffalo

    Directory of Open Access Journals (Sweden)

    M. Van Sanh

    2010-02-01

    Full Text Available Eight Swamp buffalo bulls (4 large and 4 local small sized and 240 buffalo cows (120 selected and 120 non-selected were used to evaluate the effects of bull size and selected cows on body weight of calves. Experimental animals were allocated into 4 groups: T1- large sized bulls x selected cows (BSB+SC; T2 - large sized bulls x non-selected cows (BSB+NSC; T3 – local small sized bulls x selected cows (SSB+SC and CT – local small sized bulls x non-selected cows (SSB+NSC as a control group. Each bull was mated with 15 selected cows and 15 non-selected cows. Body weight of calves at birth, 3, 6, 12 and 24 months of ages was highest in calves of T1, then T2 and then T3 while the lowest weight was found in the CT group. Calf weight in the large sized bulls and selected cows group was higher by 10-15% than that of calves in the local small bulls and non-selected cows group at all ages. It is concluded that the use of large sized bulls for breeding increased body weight of calves. Using large bulls and selected buffalo cows was the best solution for improving the body weight of the local buffalo.

  1. Head shape evolution in monitor lizards (Varanus): interactions between extreme size disparity, phylogeny and ecology.

    Science.gov (United States)

    Openshaw, G H; Keogh, J S

    2014-02-01

    Characterizing patterns of observed current variation, and testing hypotheses concerning the potential drivers of this variation, is fundamental to understanding how morphology evolves. Phylogenetic history, size and ecology are all central components driving the evolution of morphological variation, but only recently have methods become available to tease these aspects apart for particular body structures. Extant monitor lizards (Varanus) have radiated into an incredible range of habitats and display the largest body size range of any terrestrial vertebrate genus. Although their body morphology remains remarkably conservative, they have obvious head shape variation. We use two-dimensional geometric morphometric techniques to characterize the patterns of dorsal head shape variation in 36 species (375 specimens) of varanid, and test how this variation relates to size, phylogenetic history and ecology as represented by habitat. Interspecific head shape disparity is strongly allometric. Once size effects are removed, principal component analysis shows that most shape variation relates to changes in the snout and head width. Size-corrected head shape variation has strong phylogenetic signal at a broad level, but habitat use is predictive of shape disparity within phylogenetic lineages. Size often explains shape disparity among organisms; however, the ability to separate size and shape variation using geometric morphometrics has enabled the identification of phylogenetic history and habitat as additional key factors contributing to the evolution of head shape disparity among varanid lizards.

  2. Simultaneous analysis of small organic acids and humic acids using high performance size exclusion chromatography

    NARCIS (Netherlands)

    Qin, X.P.; Liu, F.; Wang, G.C.; Weng, L.P.

    2012-01-01

    An accurate and fast method for simultaneous determination of small organic acids and much larger humic acids was developed using high performance size exclusion chromatography. Two small organic acids, i.e. salicylic acid and 2,3-dihydroxybenzoic acid, and one purified humic acid material were used

  3. Predictable variation of range-sizes across an extreme environmental gradient in a lizard adaptive radiation: evolutionary and ecological inferences.

    Directory of Open Access Journals (Sweden)

    Daniel Pincheira-Donoso

    Full Text Available Large-scale patterns of current species geographic range-size variation reflect historical dynamics of dispersal and provide insights into future consequences under changing environments. Evidence suggests that climate warming exerts major damage on high latitude and elevation organisms, where changes are more severe and available space to disperse tracking historical niches is more limited. Species with longer generations (slower adaptive responses, such as vertebrates, and with restricted distributions (lower genetic diversity, higher inbreeding in these environments are expected to be particularly threatened by warming crises. However, a well-known macroecological generalization (Rapoport's rule predicts that species range-sizes increase with increasing latitude-elevation, thus counterbalancing the impact of climate change. Here, I investigate geographic range-size variation across an extreme environmental gradient and as a function of body size, in the prominent Liolaemus lizard adaptive radiation. Conventional and phylogenetic analyses revealed that latitudinal (but not elevational ranges significantly decrease with increasing latitude-elevation, while body size was unrelated to range-size. Evolutionarily, these results are insightful as they suggest a link between spatial environmental gradients and range-size evolution. However, ecologically, these results suggest that Liolaemus might be increasingly threatened if, as predicted by theory, ranges retract and contract continuously under persisting climate warming, potentially increasing extinction risks at high latitudes and elevations.

  4. The employment of graduates within small and medium sized firms in England

    OpenAIRE

    Hart, Trevor; BARRATT, Paul

    2009-01-01

    This paper reports a research study prompted by the uneven distribution of graduates between small and large businesses. In particular, it sought to understand the main drivers or impediments to recruitment of graduates by small and medium sized enterprises (SMEs) through an in-depth study of a matched sample of small firms employing and not employing graduates. It also sought to understand the nature of the benefits which might accrue to an SME from employing graduates. While some of the bar...

  5. Role of Relationship Marketing in Small and Medium-Sized Entreprises

    OpenAIRE

    Ružica Butigan; Ivana Mahnić

    2011-01-01

    Along with marketing, small and medium enterprises (SMEs) are commonly associated in literature with relationship marketing which results in marketing networks. This paper examines the specific characteristics that differentiate large companies from small and medium-sized enterprises, and the reasons that prevent SMEs from engaging in traditional marketing within the scope of marketing mix. The paper also shows that the key characteristic which distinguishes small from large companies is a pr...

  6. Small, medium, large or supersize? The development and evaluation of interventions targeted at portion size.

    Science.gov (United States)

    Vermeer, W M; Steenhuis, I H M; Poelman, M P

    2014-07-01

    In the past decades, portion sizes of high-caloric foods and drinks have increased and can be considered an important environmental obesogenic factor. This paper describes a research project in which the feasibility and effectiveness of environmental interventions targeted at portion size was evaluated. The studies that we conducted revealed that portion size labeling, offering a larger variety of portion sizes, and proportional pricing (that is, a comparable price per unit regardless of the size) were considered feasible to implement according to both consumers and point-of-purchase representatives. Studies into the effectiveness of these interventions demonstrated that the impact of portion size labeling on the (intended) consumption of soft drinks was, at most, modest. Furthermore, the introduction of smaller portion sizes of hot meals in worksite cafeterias in addition to the existing size stimulated a moderate number of consumers to replace their large meals by a small meal. Elaborating on these findings, we advocate further research into communication and marketing strategies related to portion size interventions; the development of environmental portion size interventions as well as educational interventions that improve people's ability to deal with a 'super-sized' environment; the implementation of regulation with respect to portion size labeling, and the use of nudges to stimulate consumers to select healthier portion sizes.

  7. Prognostic Importance of Small Prostate Size in Men Receiving Definitive Prostate Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Taira, Al V. [Western Radiation Oncology, Mountain View, California (United States); Merrick, Gregory S., E-mail: gmerrick@urologicresearchinstitute.org [Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, West Virginia (United States); Galbreath, Robert W.; Butler, Wayne M. [Schiffler Cancer Center, Wheeling Jesuit University, Wheeling, West Virginia (United States); Adamovich, Edward [Department of Pathology, Wheeling Hospital, Wheeling, West Virginia (United States); Wallner, Kent E. [Puget Sound Healthcare Corporation, Group Health Cooperative, University of Washington, Seattle, Washington (United States)

    2012-10-01

    Purpose: To assess whether small prostate size is an adverse prognostic factor in men undergoing brachytherapy in the same manner in which it seems to be for men undergoing radical prostatectomy. Methods and Materials: From April 1995 to June 2008, 2024 patients underwent brachytherapy by a single brachytherapist. Median follow-up was 7.4 years. The role of small prostate size ({<=}20 cm{sup 3}) as a prognostic factor for biochemical progression-free survival, cause-specific survival, and all-cause mortality was investigated. The differences in survival between men with small and larger prostates were compared using Kaplan-Meier curves and log-rank tests. Results: Median prostate size for the entire cohort was 32.7 cm{sup 3}. For the 167 men with small prostates, median prostate size was 17.4 cm{sup 3}. There was no difference in biochemical progression-free survival (95.2% vs 96.2%, P=.603), cause-specific survival (97.7% vs 98.3%, P=.546), or all-cause mortality (78.0% vs 77.2%, P=.838) at 10 years for men with small prostates compared with men with larger prostates. On univariate and multivariate analysis, small prostate size was not associated with any of the primary outcome measures. Conclusion: Men with small prostates treated with brachytherapy have excellent outcomes and are at no higher risk of treatment failure than men with larger glands. High-quality implants with adequate margins seem sufficient to address the increased adverse risk factors associated with small prostate size.

  8. Using plate mapping to examine portion size and plate composition for large and small divided plates.

    Science.gov (United States)

    Sharp, David E; Sobal, Jeffery; Wansink, Brian

    2014-12-01

    Does the size of a plate influence the serving of all items equally, or does it influence the serving of some foods - such as meat versus vegetables - differently? To examine this question, we used the new method of plate mapping, where people drew a meal on a paper plate to examine sensitivity to small versus large three-compartment divided plates in portion size and meal composition in a sample of 109 university students. The total drawn meal area was 37% bigger on large plates than small plates, which showed that the portion of plate coverage did not differ by plate size. Men and women drew bigger vegetable portions and men drew bigger meat portions on large plates when compared to small plates. These results suggest that men and women are differentially sensitive to plate size for overall meal size and for meal composition. Implications for decreasing portion size and improving meal balance are that plate size may influence portion size and change the proportions of foods served.

  9. Effect of grid size in RCMs on the representation of floods in small and medium sized catchments in Austria: added value of convection-permitting simulations

    Science.gov (United States)

    Reszler, Christian; Truhetz, Heimo; Switanek, Matthew

    2016-04-01

    This paper presents a small multi-model ensemble study of coupling two different ERA-Interim driven RCMs (WRF and COSMO-CLM) using different grid sizes (0.44°, 0.11°, 0.03°) with a hydrological model for representing floods in small to medium sized catchments in South-eastern Austria. The aim is to evaluate the benefit of grid size reduction and in particular, the added value of convection-permitting simulations with 0.03° (~ 3 km) resolution. The hydrological model is a spatially distributed model (1 km² grid), which was previously developed for operational flood forecasting and calibrated against data of more than 20 stream gauges with corresponding catchment sizes between 30 and 1000 km². The hindcast simulations (1989-2010) are evaluated in terms of accurately representing flood frequency, seasonality, as well as other flood event characteristics, such as weather type, antecedent soil moisture, etc. The results show, that for small catchments (frequency and seasonality is represented well in all catchments. In the larger catchments a resolution of 0.11° (~ 12.5 km) already yields statistically satisfying results. Also, due to the short response times in the small sub-catchments a time step of 1 hour is required. However, in all setups a bias still exists in precipitation and temperature, which sometimes leads to unrealistic hydrological conditions. Ongoing work comprises the test a of novel statistical error correction method, which is expected to improve results particularly for higher quantiles. Also, a future run ("time-slice" experiment) is planned with the coupled model setup using the RCP8.5 emission scenario, the GCM of the Max-Planck-Institute Hamburg (MPI-ESM-LR), dynamically downscaled to 3 km by COSMO-CLM, and the novel error correction method. The study is funded by the Austrian Klima- und Energiefonds through the Austrian Climate Research Programme (ACRP) by means of the project CHC-FloodS (id KR13AC6K11102). Further support is also received

  10. Assessing future climatic changes of rainfall extremes at small spatio-temporal scales

    DEFF Research Database (Denmark)

    Gregersen, Ida Bülow; Sørup, Hjalte Jomo Danielsen; Madsen, Henrik;

    2013-01-01

    in relation to urban flooding. The present study focuses on high-resolution regional climate model (RCM) skill in simulating sub-daily rainfall extremes. Temporal and spatial characteristics of output from three different RCM simulations with 25 km resolution are compared to point rainfall extremes estimated......Climate change is expected to influence the occurrence and magnitude of rainfall extremes and hence the flood risks in cities. Major impacts of an increased pluvial flood risk are expected to occur at hourly and sub-hourly resolutions. This makes convective storms the dominant rainfall type...

  11. Sinusoidal microcirculatory changes after small-for-size liver transplantation in rats.

    Science.gov (United States)

    Li, Junjian; Liang, Liang; Ma, Tao; Yu, Xiazhen; Chen, Wei; Xu, Guodong; Liang, Tingbo

    2010-09-01

    Small-for-size graft injury is characterized by portal venous hypertension and loss of intracellular homeostasis early after transplant. The long-term alteration of sinusoidal microcirculatory hemodynamic state remains unknown. A syngeneic rat orthotopic liver transplantation model was developed using small-for-size grafts (35% of recipient liver weight) or whole grafts (100% of recipient liver weight). Graft survival, portal pressure, liver function, hepatocellular apoptosis as well as morphological changes (by light microscopy and electron microscopy) were assessed. Sinusoidal microcirculatory hemodynamics was examined by intravital fluorescence microscopy. Although portal hypertension lasted only for 1 h after performance of small-for-size liver transplantation, a sustained microcirculatory disturbance was accompanied by dramatic reduction of sinusoidal perfusion rate, elevation of sinusoidal diameter as well as increase in the number of apoptotic hepatocytes during the first 7 days. These resulted in lower survival rate (50% vs. 100%, P = 0.012), higher level of liver function, and more severe morphological changes, which could induce small-for-size syndrome. In conclusion, persistent microcirculatory hemodynamic derangement during the first 7 days after reperfusion as well as transient portal hypertension is significant manifestation after small-for-size liver transplantation. Long-term microcirculation disturbance displayed as decrease of sinusoidal reperfusion area and increase of spread in functional liver mass seems to be the key factor for graft injuries.

  12. Human resources management within the process management in small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Marie Duspivová

    2013-01-01

    Full Text Available Sector of small and medium-sized enterprises is regarded as the backbone of the economy and a driving force of innovation, employment and social integration. Development of the sector of small and medium-sized enterprises in the Czech Republic has a substantial impact on economic and social development of the country and its various regions. This article deals with the human resources management in small and medium-sized enterprises, because it is more than obvious recently that the prosperity of the organization is depended on human resources and management of them can determine not only whether the organizations succeed, but whether it will be able to survive in turbulent conditions in the present world. The main aim of this paper is to analytical describe the monitoring the process of human resources management in selected categories of enterprises by business activity and number of employees including statistical analysis of causal effects. Further to analytical describe the evaluation the process of human resources management and indicators of this process, which are monitored by small and medium-sized enterprises. To achieve this aim were used selected primary data collected in the project GAJU 068/2010/S titled “Process management and its possible implementation in small and medium-sized enterprises”.

  13. 40 CFR 141.81 - Applicability of corrosion control treatment steps to small, medium-size and large water systems.

    Science.gov (United States)

    2010-07-01

    ... treatment steps to small, medium-size and large water systems. 141.81 Section 141.81 Protection of... to small, medium-size and large water systems. (a) Systems shall complete the applicable corrosion...) or (b)(3) of this section. (2) A small system (serving ≤3300 persons) and a medium-size system...

  14. The challenges and utilization of e-commerce : use of Internet by small to medium-sized enterprises in the United Kingdom

    OpenAIRE

    Lawrence, Japhet Eke

    2008-01-01

    The Internet is portrayed by the media, academia and IT professionals as a new frontier that will transform and revolutionise the way business is conducted globally. The contribution of small to medium-sized enterprises (SMEs) is extremely important to the economy of many countries and their contribution cannot be over-emphasised. SMEs account for more than 50% of private-sector employment in the UK and currently are contributing most of the private sector employment growth. Information techn...

  15. Small-Sized, Flat-Type Invasive Branch Duct Intraductal Papillary Mucinous Neoplasm: A Case Report

    Directory of Open Access Journals (Sweden)

    Koji Shindo

    2013-10-01

    Full Text Available Recent improvements in diagnostic modalities are increasing the frequency of detection of small-sized branch duct intraductal papillary mucinous neoplasms (BD-IPMNs. International consensus guidelines for IPMN recommend surveillance without immediate resection for small-sized (<3 cm BD-IPMNs without malignant features on imaging. Our patient is the first to have undergone resection of a small-sized BD-IPMN containing invasive cancer, but without malignant features on imaging. We herein report a case involving a 70-year-old man with a small cystic lesion in the pancreas head detected by health screening ultrasonography. Detailed examination revealed that the cystic lesion was a BD-IPMN measuring about 2 cm, with no malignant features. However, cytological examination of the pancreatic juice showed atypical cells with high-grade dysplasia storing intracytoplasmic mucin, indicating malignant BD-IPMN. Pathological examination of the resected specimen showed a BD-IPMN measuring 16 mm with an associated invasive carcinoma that invaded the pancreatic parenchyma over a distance of 11 mm. In this patient, invasive cancer was present within a small BD-IPMN with no high-risk stigmata on imaging. Cytological examination of the pancreatic juice allowed for the detection of pancreatic cancer in such a small-sized IPMN. Although routine endoscopic retrograde cholangiopancreatography (ERCP with cytology is not recommended in all patients with BD-IPMNs, ERCP may contribute to the detection of small pancreatic cancers in select cases. Accumulation of cases of pancreatic cancer within small BD-IPMNs may help establish the indications for ERCP with cytological examination for the purpose of early detection of small pancreatic cancer.

  16. Influence of fruit ripening acceleration measures on flowering and fruiting of small-sized tomato

    Directory of Open Access Journals (Sweden)

    Renata Dobromilska

    2012-12-01

    Full Text Available The investigations were carried out in 2001-2003 at the Horticulture Experimental Station, University of Agriculture in Szczecin. The influence of truss cutting and application of Ethrel preparation on the flowering and acceleration of ripening of small-sized tomato fruit was studied. The experiment focused on the following factors: methods of acceleration of tomato fruit ripening (truss cutting, Ethrel preparation, truss cutting + Ethrel preparation and tomato cultivars ('Cheresita F1', 'Favorita F1'. The applied methods had no influence on the number of flowers and germs of the small-sized tomato. The truss cutting increased the percentage of set fruits compared to the number of flowers. The application of Ethrel preparation along with truss cutting significantly increased the early yield of tomato fruits. The Ethrel and truss cutting accelerated the small-sized tomato harvesting by 12 days. Cv. 'Cheresita F1' produced a larger number of flowers, germs and fruits than 'Favorita F1'.

  17. SMALL AND MEDIUM-SIZE ENTERPRISES AS A FORM OF ENTREPRENEURSHIP IN RURAL AREAS

    Directory of Open Access Journals (Sweden)

    Maria Bucka

    2014-06-01

    Full Text Available In rural areas, we are now dealing with a surplus of labour in agriculture and lack of jobs for the population without land. The decreasing role of agriculture and the benefits of agricultural production as a primary source of income of the rural population makes it necessary to supplement income from other activities. Making activities in the sector of small and medium-sized enterprises can significantly be replenished. Small and medium-sized enterprises can be regarded as a manifestation of entrepreneurship in rural areas. The aim of the study is to identify the role and importance of small and medium-sized enterprises in rural activation. In this study, the statistical material available from GUS contained in the publications concerning rural areas in Poland and literature.

  18. The Cherenkov Telescope Array single-mirror small size telescope project: status and prospects

    Science.gov (United States)

    Aguilar, J. A.; Bilnik, W.; Bogacz, L.; Bulik, T.; Christov, A.; della Volpe, D.; Dyrda, M.; Frankowski, A.; Grudzińska, M.; Grygorczuk, J.; Heller, M.; Idźkowski, B.; Janiak, M.; Jamrozy, M.; Karczewski, M.; Kasperek, J.; Lyard, E.; Marszalek, A.; Michalowski, J.; Rameez, M.; Moderski, R.; Montaruli, T.; Neronov, A.; Nicolau-Kukliński, J.; Niemiec, J.; Ostrowski, M.; Paśko, P.; Płatos, Ł.; Prandini, E.; Rafalski, J.; Rajda, P. J.; Rataj, M.; Rupiński, M.; Rutkowskai, K.; Seweryn, K.; Sidz, M.; Stawarz, Ł.; Stodulska, M.; Stodulski, M.; Tokarz, M.; Toscano, S.; Troyano Pujadas, I.; Walter, R.; Wawer, P.; Wawrzaszek, R.; Wiśniewski, L.; Winiarski, K.; Zietara, K.; Ziółkowski, P.; Źychowski, P.

    2014-07-01

    The Cherenkov Telescope Array (CTA), the next generation very high energy gamma-ray observatory, will consist of three types of telescopes: large (LST), medium (MST) and small (SST) size telescopes. The small size telescopes are dedicated to the observation of gamma-rays with energy between a few TeV and few hundreds of TeV. The single-mirror small size telescope (SST-1M) is one of several SST designs. It will be equipped with a 4 m-diameter segmented mirror dish and a fully digital camera based on Geiger-mode avalanche photodiodes. Currently, the first prototype of the mechanical structure is under assembly in Poland. In 2014 it will be equipped with 18 mirror facets and a prototype of the camera.

  19. Improvement of environmental management incentives for small and medium-sized enterprises

    Energy Technology Data Exchange (ETDEWEB)

    Chang, Kee Bok; Lee, Seung Kyu; Lim, Chae Woon; Chung, Ho Sun [Korea Environment Institute, Seoul (Korea)

    1998-12-01

    The developed countries have been prepared the national innovation for sustainable development for a long time. The international advanced enterprises, such as multinational enterprises, are enhancing the active and strategic environmental management. However, in spite of such changes in the world, small and middle-sized enterprises do not show any substantial changes. It is true that most of enterprises do not recognize the need of environmental management. Although they have intention for environmental improvement, it is also true that they do not have any strength to maintain effective management. Moreover, with over 99% of small and middle-sized enterprises among entire enterprises in Korea, it is hardly possible to establish an effective regulation system. The purpose of this study is to make a policy plan to induce the development of environmental friendly small and middle-sized enterprises under the recognition of such problems. 138 refs., 4 figs., 195 tabs.

  20. Highly Directional Small-Size Antenna Designed with Homogeneous Transformation Optics

    Directory of Open Access Journals (Sweden)

    Zuojia Wang

    2014-01-01

    Full Text Available Achieving high directivity antenna usually requires a large size antenna aperture in traditional antenna design. Previous work shows that, with the help of metamaterials and transformation optics, a small size antenna can perform as high directivity as a large size antenna, but the material parameters are inhomogeneous and difficult to realize. In this paper, we propose a linear homogeneous coordinate transformation to design the small size antenna. Distinguishing from inhomogeneous transformation, we construct a regular polygon in virtual space and then divide it into several triangle segments. By applying linear homogeneous coordinate transformation, the antenna devices can be greatly compressed without disturbing the radiation patterns by using homogeneous metamaterial substrates. The material parameters of the antenna designed from this method are homogeneous and easy to fabricate. Square and hexagonal antenna structures are numerically demonstrated to illustrate the validity of our methodology.

  1. Body size and walking cadence affect lower extremity joint power in children's gait.

    Science.gov (United States)

    Shultz, Sarah P; Hills, Andrew P; Sitler, Michael R; Hillstrom, Howard J

    2010-06-01

    Obese children move less and with greater difficulty than normal-weight counterparts but expend comparable energy. Increased metabolic costs have been attributed to poor biomechanics but few studies have investigated the influence of obesity on mechanical demands of gait. This study sought to assess three-dimensional lower extremity joint powers in two walking cadences in 28 obese and normal-weight children. 3D-motion analysis was conducted for five trials of barefoot walking at self-selected and 30% greater than self-selected cadences. Mechanical power was calculated at the hip, knee, and ankle in sagittal, frontal and transverse planes. Significant group differences were seen for all power phases in the sagittal plane, hip and knee power at weight acceptance and hip power at propulsion in the frontal plane, and knee power during mid-stance in the transverse plane. After adjusting for body weight, group differences existed in hip and knee power phases at weight acceptance in sagittal and frontal planes, respectively. Differences in cadence existed for all hip joint powers in the sagittal plane and frontal plane hip power at propulsion. Frontal plane knee power at weight acceptance and sagittal plane knee power at propulsion were significantly different between cadences. Larger joint powers in obese children contribute to difficulty performing locomotor tasks, potentially decreasing motivation to exercise.

  2. Development of an Autonomous Flight Control System for Small Size Unmanned Helicopter Based on Dynamical Model

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    It is devoted to the development of an autonomous flight control system for small size unmanned helicopter based on dynamical model. At first, the mathematical model of a small size helicopter is described. After that simple but effective MTCV control algorithm was proposed. The whole flight control algorithm is composed of two parts:orientation controller based on the model for rotation dynamics and a robust position controller for a double integrator. The MTCV block is also used to achieve translation velocity control. To demonstrate the performance of the presented algorithm, simulation results and results achieved in real flight experiments were presented.

  3. The bat genome: GC-biased small chromosomes associated with reduction in genome size.

    Science.gov (United States)

    Kasai, Fumio; O'Brien, Patricia C M; Ferguson-Smith, Malcolm A

    2013-12-01

    Bats are distinct from other mammals in their small genome size as well as their high metabolic rate, possibly related to flight ability. Although the genome sequence has been published in two species, the data lack cytogenetic information. In this study, the size and GC content of each chromosome are measured from the flow karyotype of the mouse-eared bat, Myotis myotis (MMY). The smaller chromosomes are GC-rich compared to the larger chromosomes, and the relative proportions of homologous segments between MMY and human differ among the MMY chromosomes. The MMY genome size calculated from the sum of the chromosome sizes is 2.25 Gb, and the total GC content is 42.3%, compared to human and dog with 41.0 and 41.2%, respectively. The GC-rich small MMY genome is characterised by GC-biased smaller chromosomes resulting from preferential loss of AT-rich sequences. Although the association between GC-rich small chromosomes and small genome size has been reported only in birds so far, we show in this paper, for the first time, that the same phenomenon is observed in at least one group of mammals, implying that this may be a mechanism common to genome evolution in general.

  4. Small Business Failure Rates: Choice of Definition and the Size Effect

    OpenAIRE

    1996-01-01

    Results of many previous studies on the rate of small business failure suggest an inverse relationship between size of business and propensity to fail. However, it has been suggested that this inverse relationship, between firm size and the rate of discontinuance, may more accurately be characterized as an inverse relationship between age of business and the rate of discontinuance. While some studies have confirmed the positive association between failure and age, they have generally found th...

  5. PERFORMANCE-DRIVEN BUSINESS PROCESS MANAGEMENT METHODOLOGY FOR SMALL AND MEDIUM SIZED-ENTERPRISES

    Institute of Scientific and Technical Information of China (English)

    Tang Hongtao; Tang Renzhong

    2004-01-01

    Based on the analysis of the common limitations of business process management (BPM) methodologies and the requirements of small and medium sized-enterprises (SMEs), the importance of a "performance construct" of BPM methodologies is identified, a six-phase performance-driven BPM methodology for the production and operation processes of Chinese SMEs is developed. A case study on the process management of a medium-sized enterprise shows a successful example of running the methodology.

  6. LDA measurements on the turbulent flow characteristics of a small-sized axial fan

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang Kweon [Kunsan National Univ., Kunsan (Korea, Republic of)

    2001-07-01

    The operating point of a small-sized axial fan for refrigerator is strongly dependent upon the system resistance. Therefore, the turbulent flow characteristics around a small-sized axial fan may change significantly according to the operating point. This study represents three-dimensional turbulent flow characteristics around a small-sized axial fan measured at the four operating points such as {phi}=0.1, 0.18, 0.25 and 0.32 by using fiber-optic type LDA system. This LDA system is composed of a 5 W Argon-ion laser, two optics in back-scatter mode, three BSA's, a PC, and a three-dimensional automatic traversing system. A kind of paraffin fluid is utilized for supplying particles by means of fog generator. Mean velocity profiles downstream of a small--sized axial fan along the radial distance show that both the streamwise and the tangential components exist predominantly in downstream except {phi}=0.1 and have a maximum value at the radial distance ratio of about 0.8, but the radial component, which its velocity is relatively small, is acting role that only turns flow direction to the outside or the central part of axial fan. Moreover, all of the velocity components downstream at {phi}=0.1 show much smaller than those upstream due to the static pressure rise at the low-flowrate region.

  7. Development of Harvesting Machines for Willow Small-Sizes Plantations in East-Central Europe

    OpenAIRE

    Trzepieciński, Tomasz; Stachowicz, Feliks; Niemiec, Witold; Kępa, Leszek; Dziurka, Marek

    2016-01-01

    The production of plant biomass in small farms within the Central and Eastern European countries requires the application of agricultural machines adjusted to the scale of production. In the article, new machines for small-sized plantations of energy crops have been presented. Furthermore, the results of strength analysis of three-point linkage mower frame are presented by finite element method. The advantage of the proposed solutions is their simple construction, which is connected with low ...

  8. Deep learning in the small sample size setting: cascaded feed forward neural networks for medical image segmentation

    Science.gov (United States)

    Gaonkar, Bilwaj; Hovda, David; Martin, Neil; Macyszyn, Luke

    2016-03-01

    Deep Learning, refers to large set of neural network based algorithms, have emerged as promising machine- learning tools in the general imaging and computer vision domains. Convolutional neural networks (CNNs), a specific class of deep learning algorithms, have been extremely effective in object recognition and localization in natural images. A characteristic feature of CNNs, is the use of a locally connected multi layer topology that is inspired by the animal visual cortex (the most powerful vision system in existence). While CNNs, perform admirably in object identification and localization tasks, typically require training on extremely large datasets. Unfortunately, in medical image analysis, large datasets are either unavailable or are extremely expensive to obtain. Further, the primary tasks in medical imaging are organ identification and segmentation from 3D scans, which are different from the standard computer vision tasks of object recognition. Thus, in order to translate the advantages of deep learning to medical image analysis, there is a need to develop deep network topologies and training methodologies, that are geared towards medical imaging related tasks and can work in a setting where dataset sizes are relatively small. In this paper, we present a technique for stacked supervised training of deep feed forward neural networks for segmenting organs from medical scans. Each `neural network layer' in the stack is trained to identify a sub region of the original image, that contains the organ of interest. By layering several such stacks together a very deep neural network is constructed. Such a network can be used to identify extremely small regions of interest in extremely large images, inspite of a lack of clear contrast in the signal or easily identifiable shape characteristics. What is even more intriguing is that the network stack achieves accurate segmentation even when it is trained on a single image with manually labelled ground truth. We validate

  9. Gluconeogenesis differs in developing chick embryos derived from small compared with typical size broiler breeder eggs.

    Science.gov (United States)

    Sunny, N E; Bequette, B J

    2010-03-01

    We hypothesized that, as the supply of preformed glucose diminishes during development, the embryo would transition to a greater rate of gluconeogenesis (GNG) and that GNG would be greater in embryos from small vs. typical size eggs. Gluconeogenesis by embryos from small (51.1 +/- 3.46 g) and typical size (65 +/- 4.35 g) broiler breeder eggs was measured by dosing [(13)C(6)]glucose (15 mgxegg(-1)) into the chorio-allantoic fluid for 3 consecutive days to achieve isotopic steady-state before blood collection on embryonic day (e) 12, e14, e16, and e18 (4 to 5 eggsxsize(-1)xd(-1)). The (13)C-Mass isotopomer enrichment of blood glucose was determined by gas chromatography-mass spectrometry. On e14, e16, and e18, but not on e12, embryos from small eggs weighed less (P Cori cycling and glucose (13)C-recycling (% of entry rate) increased (P Cori cycle flux were greater (P Cori and non-Cori cycle fluxes were greater for embryos from small eggs. From e12 through e18, blood concentrations of gluconeogenic AA (threonine, glutamine, arginine, proline, isoleucine, and valine) were 25 to 48% less (P < 0.01) in embryos from small eggs. In conclusion, embryos from small eggs exhibit greater rates of GNG earlier in development compared with typical size eggs and, perhaps as a consequence, their reduced embryonic growth may result from diverting greater supplies of AA toward GNG.

  10. Identifying neutrino mass hierarchy at extremely small theta13 through earth matter effects in a supernova signal.

    Science.gov (United States)

    Dasgupta, Basudeb; Dighe, Amol; Mirizzi, Alessandro

    2008-10-24

    Collective neutrino flavor transformations deep inside a supernova are sensitive to the neutrino mass hierarchy even at extremely small values of theta_(13). Exploiting this effect, we show that comparison of the antineutrino signals from a galactic supernova in two megaton class water Cherenkov detectors, one of which is shadowed by Earth, will enable us to distinguish between the hierarchies if sin(2)theta_(13) < or approximately 10(-5), where long baseline neutrino experiments would be ineffectual.

  11. A dearth of small particles in debris disks: An energy-constrained smallest fragment size

    CERN Document Server

    Krijt, Sebastiaan

    2014-01-01

    A prescription for the fragment size distribution resulting from dust grain collisions is essential when modelling a range of astrophysical systems, such as debris disks and planetary rings. While the slope of the fragment size distribution and the size of the largest fragment are well known, the behaviour of the distribution at the small size end is theoretically and experimentally poorly understood. This leads debris disk codes to generally assume a limit equal to, or below, the radiation blow-out size. We use energy conservation to analytically derive a lower boundary of the fragment size distribution for a range of collider mass ratios. Focussing on collisions between equal-sized bodies, we apply the method to debris disks. For a given collider mass, the size of the smallest fragments is found to depend on collision velocity, material parameters, and the size of the largest fragment. We provide a physically motivated recipe for the calculation of the smallest fragment, which can be easily implemented in c...

  12. The prediction of bankruptcy of small- and medium-sized industrial firms

    NARCIS (Netherlands)

    Pompe, P.P.M.; Bilderbeek, J.

    2005-01-01

    Using large amounts of data from small- and medium-sized industrial firms, this study examines several aspects of bankruptcy prediction. We have tested a hypothesis on the predictive power of different ratio categories during the successive phases before bankruptcy, and one on the relationship

  13. New Balancing Equipment for Mass Production of Small and Medium-Sized Electrical Machines

    DEFF Research Database (Denmark)

    Argeseanu, Alin; Ritchie, Ewen; Leban, Krisztina Monika

    2010-01-01

    The level of vibration and noise is an important feature. It is good practice to explain the significance of the indicators of the quality of electrical machines. The mass production of small and medium-sized electrical machines demands speed (short typical measurement time), reliability...

  14. The prediction of bankruptcy of small- and medium-sized industrial firms

    NARCIS (Netherlands)

    Pompe, Paul P.M.; Bilderbeek, Jan

    2005-01-01

    Using large amounts of data from small- and medium-sized industrial firms, this study examines several aspects of bankruptcy prediction. We have tested a hypothesis on the predictive power of different ratio categories during the successive phases before bankruptcy, and one on the relationship betwe

  15. Small sized high-gain PHEMT high-power amplifiers for X-band applications

    NARCIS (Netherlands)

    Hek, A.P. de; Hunneman, P.A.H.

    2000-01-01

    The development of two small sized broadband X-band high-power amplifiers is discussed. The amplifiers are realised with the help of the pseudomorphic HEMT technology of the Fraunhofer Institute for Applied Solid State Physics (FhG-IAF). With the help of this technology the feasibility of

  16. Continuing Education for Managers from Small and Medium Sized German Companies.

    Science.gov (United States)

    Fub, Jorg

    1995-01-01

    An international trade school in southern Germany, which is a highly export-oriented environment, has established a vocational and professional continuing education program for personnel of small- and medium-size companies. Offerings include a graduate course in international marketing, seminars for export companies, distance education in…

  17. Analyses of transverse vibrations of axially pretensioned viscoelastic nanobeams with small size and surface effects

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Yongqiang [College of Civil Engineering and Architecture, Zhejiang University, Hangzhou 310058 (China); State Key Laboratory of Mechanical Structural Strength and Vibration, Xi' an Jiaotong University, Xi' an 710049 (China); Pang, Miao, E-mail: ppmmzju@163.com [College of Civil Engineering and Architecture, Zhejiang University, Hangzhou 310058 (China); Fan, Lifeng [College of Civil Engineering and Architecture, Zhejiang University, Hangzhou 310058 (China)

    2016-07-01

    The general governing equation for transverse vibration of an axially pretensioned viscoelastic nanobeam embedded in elastic substrate medium is formulated on the basis of the Bernoulli–Euler beam theory and the Kelvin model. The factors of structural damping, initial axial tension, surrounding medium, small size, surface elasticity and residual surface tension are incorporated in the formulation. The explicit expression is obtained for the vibrational frequency of a simply supported nanobeam. The impacts of these factors on the properties of transverse vibration of the nanobeam are discussed. It is demonstrated that the dependences of natural frequency on the structural damping, surrounding medium, small size, surface elasticity and residual surface tension are significant, whereas the effect of initial axial tension on the natural frequency is limited. In addition, it can be concluded that the energy dissipation of transverse vibration of the viscoelastic nanobeam is related to the small size effect and structural damping. - Highlights: • The properties of transverse vibration of a pretensioned embedded viscoelastic nanobeam is investigated. • The vibrational equation is formulated based on Bernoulli–Euler beam theory and Kelvin model. • Explicit expression for the complex vibrational frequency is obtained. • Small size and surface effects on vibrational frequency are discussed. • Influences of structural damping, initial axial tension and surrounding medium are analyzed.

  18. Transformational and transactional leadership: does it work in small to medium-sized enterprises?

    NARCIS (Netherlands)

    Mesu, J.K.

    2013-01-01

    Using a sample of 755 employees who rated 121 supervisors within 50 Dutch small and medium-sized enterprises (SMEs), this dissertation intends to fill in some of the existing gaps in the literature. Firstly, by investigating whether the impact of transformational and transactional leadership extends

  19. The Dynamics of Small-Sized Ensembles of the Phase-Locked Loops with Unidirectional Couplings

    Science.gov (United States)

    Aleshin, K. N.; V. Matrosov, V.; Shalfeev, V. D.

    2016-06-01

    We study collective dynamics of a small-sized chain of the unidirectionally coupled phase-locked loop. The conditions for the synchronous-regime existence are found, the asynchronous selfoscillation regimes and the transitions among them are studied, and the property of inheriting the structure of the parameter space of the chain when a new element is added to it is established.

  20. A compentence-based approach for small and medium-sized enterprises

    NARCIS (Netherlands)

    Brancatisano, Germano; Jurriëns, Jan; Verburg, Robert

    2012-01-01

    On the basis of empirical research, a competence-based model of the internationalization process of Small and Medium-sized Enterprises (SMEs) is developed. The model focuses on so-called International Market-Entry Core Competencies (IMECC), which are global management competences considered crucial

  1. Small and Medium-Sized Information Technology Firms: Assessment of Non-Local Partnership Facilitators

    Science.gov (United States)

    Findikoglu, Melike Nur

    2012-01-01

    A two-phased qualitative study was conducted to explore the facilitators of non-local (i.e. domestic or international) partnerships formed by small- and medium-sized firms (SME). Rooted in trust, proximity and dynamic capabilities lenses, the study focused on behaviors of SMEs performing in dynamic, competitive and highly interlinked industry, the…

  2. Identification of Financial Strategy in Small and Medium‑sized Entrepreneurship

    Directory of Open Access Journals (Sweden)

    Veronika Svatošová

    2017-01-01

    Full Text Available This paper deals with the importance of financial strategy development of small and medium‑sized enterprises (SMEs in the winery industry. The main objective of the paper is to identify the current financial strategy of small and medium‑sized enterprises and afterwards to propose changes that lead to new financial strategy. The research methods are the selected methods of financial analysis, collecting data about the research sample of SMEs, modelling the financial strategy with the help of Vensim program and further simulation of this model in business practice. The model derives from the previous research activities. The purpose of this paper is also to verify the usage of theoretically created model in small and medium‑sized entrepreneurship and find the optimal financial strategy in the area examined. The results of this paper show the selected area of small and medium‑sized entrepreneurship uses mainly the financial strategy of maximum liquidity (conservative strategy in all observed years (2010–2014. This means the selected research sample of SMEs do not use progressive investment strategy with a further development. This result could highlight that SMEs in agricultural sector do not meet the financial strategy with corporate strategy focused on other business development. It is recommended to change this strategy into balancedfinancial strategy focused on higher profitability that could be used for the other expansion and development of the company.

  3. A compentence-based approach for small and medium-sized enterprises

    NARCIS (Netherlands)

    Germano Brancatisano; Jan Jurriëns; Robert Verburg

    2012-01-01

    On the basis of empirical research, a competence-based model of the internationalization process of Small and Medium-sized Enterprises (SMEs) is developed. The model focuses on so-called International Market-Entry Core Competencies (IMECC), which are global management competences considered crucial

  4. Energetic Communities: Planning support for sustainable energy transition in small- and medium-sized communities

    NARCIS (Netherlands)

    Sager-Klauß, C.V.

    2016-01-01

    Small- and medium-sized communities might prove to be game-changers in the overall energy transition because many problems have to be solved within their ambit. Urban planning is dealing with the numerous processes of urban change. Energy is a fairly new task to be addressed and many stakeholders la

  5. An Agile Methodology for Implementing Service-Oriented Architecture in Small and Medium Sized Organizations

    Science.gov (United States)

    Laidlaw, Gregory

    2013-01-01

    The purpose of this study is to evaluate the use of Lean/Agile principles, using action research to develop and deploy new technology for Small and Medium sized enterprises. The research case was conducted at the Lapeer County Sheriff's Department and involves the initial deployment of a Service Oriented Architecture to alleviate the data…

  6. Leadership and Organizational Learning: Accounting for Variances in Small-Size Business Enterprises

    Science.gov (United States)

    Graham, Carroll M.; Nafukho, Fredrick M.

    2007-01-01

    This study's primary purpose was to determine the relationship between leadership and the dependent variable organizational learning readiness at three locations of a small-size business enterprise in the Mid-Western United States. Surveys were acquired within an exploratory correlational research design and the results indicated leadership…

  7. Based on the AHP Small and Medium-Sized Enterprise Supply Chain Supplier Evaluation Research

    Directory of Open Access Journals (Sweden)

    Xianwu Hu

    2013-05-01

    Full Text Available In this study, we establish the evaluation index system based on the AHP small and medium-sized enterprise and then use AHP decide the weight of each evaluation index. Moreover, we use Linear Weighting Method to study supplier performance from perspective of quantitative research and give the measurement process. The empirical research, to validate the method is scientific and feasible.

  8. 77 FR 58755 - Small Business Size Standards: Health Care and Social Assistance

    Science.gov (United States)

    2012-09-24

    ... ADMINISTRATION 13 CFR Part 121 RIN 3245-AG30 Small Business Size Standards: Health Care and Social Assistance... Classification System (NAICS) Sector 62, Health Care and Social Assistance, and retaining the current standards... up with changes in the economy, in particular the changes in the Federal contracting marketplace and...

  9. Supporting the E-Business Readiness of Small and Medium-Sized Enterprises: Approaches and Metrics.

    Science.gov (United States)

    Jutla, Dawn; Bodorik, Peter; Dhaliwal, Jasbir

    2002-01-01

    Presents a conceptual model for governments in creating a climate that facilitates the national adoption of e-business. Focuses on the needs of small and medium-sized enterprises, suggests measures to assess how a country is performing in providing a positive e-business climate, and provides examples from Canada, The Netherlands, Norway, and…

  10. Hedging Behavior in Small and Medium-sized Enterprises: The Role of Unobserved Heterogeneity

    NARCIS (Netherlands)

    Pennings, J.M.E.; Garcia, P.

    2004-01-01

    Abstract We investigate factors that drive derivative usage in small and medium-sized enterprises (SMEs). The influence of these factors on hedging behavior cannot a priori be assumed equal for all SMEs. To address this heterogeneity, a generalized mixture regression model is used which classifies f

  11. An Agile Methodology for Implementing Service-Oriented Architecture in Small and Medium Sized Organizations

    Science.gov (United States)

    Laidlaw, Gregory

    2013-01-01

    The purpose of this study is to evaluate the use of Lean/Agile principles, using action research to develop and deploy new technology for Small and Medium sized enterprises. The research case was conducted at the Lapeer County Sheriff's Department and involves the initial deployment of a Service Oriented Architecture to alleviate the data…

  12. The internationalization process of small and medium-sized enterprises : An evaluation of stage theory

    NARCIS (Netherlands)

    Gankema, H.G.J.; Snuif, H.R.; Zwart, P.S.

    2000-01-01

    The aim of this study is to provide better insight into the internationalization process of small and medium-sized enterprises (SMEs). Using a five-year panel dataset and a relatively new technique, DEL analysis, the predictive validity of the export stage concept of Cavusgil's innovation-related

  13. Implementation of Lean Six Sigma in small- and medium-sized manufacturing enterprises in the Netherlands

    NARCIS (Netherlands)

    Timans, W.; Antony, J.; Ahaus, K.; van Solingen, R.

    In this paper we provide an exploration and analysis of Lean Six Sigma (LSS) implementation in Dutch manufacturing/engineering small- and medium-sized enterprises (SMEs). Critical success factors (CSFs) and impeding factors are identified and analysed. Exploratory empirical evidence about LSS

  14. Culture, Organizational Learning and Selected Employee Background Variables in Small-Size Business Enterprises

    Science.gov (United States)

    Graham, Carroll M.; Nafukho, Fredrick Muyia

    2007-01-01

    Purpose: The purpose of this study is to determine the relationship between four independent variables educational level, longevity, type of enterprise, and gender and the dependent variable culture, as a dimension that explains organizational learning readiness in seven small-size business enterprises. Design/methodology/approach: An exploratory…

  15. Accounting for logistics’ costs at small and middle-sized commercial enterprises

    OpenAIRE

    Kowalak, Robert

    2016-01-01

    Possibilities of using accounting for logistics’ costs at small and middle-sized commercial enterprises have been presented in the article. These enterprises have to compete with large-scale commercial networks, which causes the necessity of optimization of transport and storage costs.

  16. Transformational and transactional leadership: does it work in small to medium-sized enterprises?

    NARCIS (Netherlands)

    Mesu, J.K.

    2013-01-01

    Using a sample of 755 employees who rated 121 supervisors within 50 Dutch small and medium-sized enterprises (SMEs), this dissertation intends to fill in some of the existing gaps in the literature. Firstly, by investigating whether the impact of transformational and transactional leadership extends

  17. An Agile Methodology for Implementing Service-Oriented Architecture in Small and Medium Sized Organizations

    Science.gov (United States)

    Laidlaw, Gregory

    2013-01-01

    The purpose of this study is to evaluate the use of Lean/Agile principles, using action research to develop and deploy new technology for Small and Medium sized enterprises. The research case was conducted at the Lapeer County Sheriff's Department and involves the initial deployment of a Service Oriented Architecture to alleviate the data…

  18. Regularization Methods for Fitting Linear Models with Small Sample Sizes: Fitting the Lasso Estimator Using R

    Science.gov (United States)

    Finch, W. Holmes; Finch, Maria E. Hernandez

    2016-01-01

    Researchers and data analysts are sometimes faced with the problem of very small samples, where the number of variables approaches or exceeds the overall sample size; i.e. high dimensional data. In such cases, standard statistical models such as regression or analysis of variance cannot be used, either because the resulting parameter estimates…

  19. Implementation of Lean Six Sigma in small- and medium-sized manufacturing enterprises in the Netherlands

    NARCIS (Netherlands)

    Timans, W.; Antony, J.; Ahaus, K.; van Solingen, R.

    2012-01-01

    In this paper we provide an exploration and analysis of Lean Six Sigma (LSS) implementation in Dutch manufacturing/engineering small- and medium-sized enterprises (SMEs). Critical success factors (CSFs) and impeding factors are identified and analysed. Exploratory empirical evidence about LSS implem

  20. Organizational learning capability, innovation and performance: study in small and medium-sized enterprises (SMES

    Directory of Open Access Journals (Sweden)

    Giancarlo Gomes

    Full Text Available Abstract Although the relation between the organizational learning capability, organizational innovation and performance has often been studied, there is little empirical evidence to support this perspective in small and medium-sized enterprises. This study aims at analyzing the influence of organizational learning capability in innovative performance and organizational performance of small and medium-sized enterprises. The research was conducted under the quantitative approach, descriptive and causal, and cross-sectional survey. The sample was composed of 92 enterprises in the textile industry. The data were analyzed through the technique of Structural Equation Modeling. The results show that the organizational learning capability influences the innovative performance of small and medium-sized enterprises, however, the influence of the learning capability in organizational performance was not significant. The study provides evidence for these relations and shows that they are significant and positive in the context of small and medium-sized textile enterprises, context in which the empirical literature is particularly scarce. For future research it is suggested to evaluate contingency factors for innovative and organizational performance. Other studies could analyze the differences in innovation between manufacturing and service sector.

  1. Barriers to Employee Training in Small and Medium Sized Enterprises: Insights and Evidences from Mauritius

    Science.gov (United States)

    Padachi, Kesseven; Bhiwajee, Soolakshna Lukea

    2016-01-01

    Purpose: Training is an important component of successful business concerns. However, although there is growing acceptance amongst scholars that small- and medium-sized enterprises (SMEs) are engines that drive economies across nations, through their contribution in terms of job creation and poverty reduction; extant research portray that these…

  2. Greening Small and Medium-Sized Enterprises: Evaluating Environmental Policy in Vietnam

    NARCIS (Netherlands)

    Van Khoa, Le

    2006-01-01

    Small and Medium-sized Enterprises (SMEs) contribute considerably to the economic and social development of bothViet Namand Ho Chi Minh City (HCMC). But at the same time this sector causes severe environmental proble

  3. Small sized high-gain PHEMT high-power amplifiers for X-band applications

    NARCIS (Netherlands)

    Hek, A.P. de; Hunneman, P.A.H.

    2000-01-01

    The development of two small sized broadband X-band high-power amplifiers is discussed. The amplifiers are realised with the help of the pseudomorphic HEMT technology of the Fraunhofer Institute for Applied Solid State Physics (FhG-IAF). With the help of this technology the feasibility of integratin

  4. 77 FR 53769 - Receipts-Based, Small Business Size Standard; Confirmation of Effective Date

    Science.gov (United States)

    2012-09-04

    ... and 171 RIN 3150-AJ14 Receipts-Based, Small Business Size Standard; Confirmation of Effective Date AGENCY: Nuclear Regulatory Commission. ACTION: Direct final rule; confirmation of effective date. SUMMARY: The U.S. Nuclear Regulatory Commission (NRC) is confirming the effective date of August 22, 2012,...

  5. Electron Emitter for small-size Electrodynamic Space Tether using MEMS Technology

    DEFF Research Database (Denmark)

    Fleron, René A. W.; Blanke, Mogens

    2004-01-01

    system with focus on electron emitter design and manufacture using micro-electro-mechanical- system (MEMS) technology. The paper addresses the system concepts of a small size electrodynamic tether mission and shows a novel electron emitter for the 1-2 mA range where altitude can be effectively affected...

  6. Supply Chain adoption in Small and Medium-Sized Enterprises (SMEs)

    DEFF Research Database (Denmark)

    Juhl, Mathias Thim; Bernon, Mike

    2016-01-01

    and customer needs. Research Approach: An exploratory case study of five small and medium sized manufacturing companies was undertaken using in-depth interviews and business reports. Combined with relevant literature, the case study interviews provide basis for a discussion on the current adoption of supply...

  7. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wipple, C.; Vosti, E.

    1997-11-01

    This report documents recent efforts of the American Textile Partnership (AMTEX) Demand Activated Manufacturing Architecture (DAMA) Project to address needs that are characterized of small to medium sized apparel manufactures and contractors. Background on the AMTEX/DAMA project and objectives for this specific efforts are discussed.

  8. Forty-Seven Milky Way-Sized, Extremely Diffuse Galaxies in the Coma Cluster

    CERN Document Server

    van Dokkum, Pieter; Merritt, Allison; Zhang, Jielai; Geha, Marla; Conroy, Charlie

    2014-01-01

    We report the discovery of 47 low surface brightness objects in deep images of a 3 x 3 degree field centered on the Coma cluster, obtained with the Dragonfly Telephoto Array. The objects have central surface brightness mu(g,0) ranging from 24 - 26 mag/arcsec^2 and effective radii r_e = 3"-10", as measured from archival Canada France Hawaii Telescope images. From their spatial distribution we infer that most or all of the objects are galaxies in the Coma cluster. This relatively large distance is surprising as it implies that the galaxies are very large: with r_e = 1.5 - 4.6 kpc their sizes are similar to those of L* galaxies even though their median stellar mass is only ~6 x 10^7 Solar masses. The galaxies are relatively red and round, with = 0.8 and = 0.74. One of the 47 galaxies is fortuitously covered by a deep Hubble Space Telescope ACS observation. The ACS imaging shows a large spheroidal object with a central surface brightness mu(g,0) = 25.8 mag/arcsec^2, a Sersic index n=0.6, and an effective radius...

  9. The Size Distribution of the Small Near Earth Asteroids from Spacewatch

    Science.gov (United States)

    Haskell, Halford; Larsen, J.

    2009-01-01

    We are currently in the process of analyzing five years of near earth asteroid detections from the Spacewatch 0.9 meter mosaic camera. These data represent images of approximately 80,000 square degrees which have been surveyed to a limiting magnitude of 21.5 using 20 second integrations. Over 1800 detections of NEAs have been made in a consistent automated fashion with attention to observing conditions. In this poster, we present a careful debiasing of the Spacewatch pointing history following the methods outlined in Jedicke, Larsen and Spahr (2003) and use the data from the survey to calculate the size distribution of small (H > 22) near earth asteroids. For these small sizes we have needed to expand the size of our survey simulations by approximately 100 orders of magnitude in order to represent very small, very hard to detect NEAs. We use the simulations to model the biases of our survey and use the actual detections to explore the size distribution. We present a detailed examination of the "dip" in the size distribution first noticed by Harris (2008) between H=19 and H= 26. Spacewatch is funded by grants from NASA's Near Earth Object Observation and Planetary Astronomy Programs, The Brinson Foundation, the estates of Richard S. Vail and Robert L. Waland and other private individuals.

  10. Species-genetic diversity correlations in habitat fragmentation can be biased by small sample sizes.

    Science.gov (United States)

    Nazareno, Alison G; Jump, Alistair S

    2012-06-01

    Predicted parallel impacts of habitat fragmentation on genes and species lie at the core of conservation biology, yet tests of this rule are rare. In a recent article in Ecology Letters, Struebig et al. (2011) report that declining genetic diversity accompanies declining species diversity in tropical forest fragments. However, this study estimates diversity in many populations through extrapolation from very small sample sizes. Using the data of this recent work, we show that results estimated from the smallest sample sizes drive the species-genetic diversity correlation (SGDC), owing to a false-positive association between habitat fragmentation and loss of genetic diversity. Small sample sizes are a persistent problem in habitat fragmentation studies, the results of which often do not fit simple theoretical models. It is essential, therefore, that data assessing the proposed SGDC are sufficient in order that conclusions be robust.

  11. Benefits of Lean transformation efforts in small- and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Urs Buehlmann

    2016-01-01

    Full Text Available This study examines the awareness, the implementation status, and the results from implementing Lean among small- and medium-sized enterprises (SMEs in two segments of Virginia’s manufacturing industry. One hundred and eighty responses from a census mail survey (population size 1033 were analyzed and the results confirm previous research that smaller enterprises in these industries are marginally aware of Lean and its potential benefits. Smaller enterprises also have implemented Lean to a lesser degree than have medium or large enterprises. Also, fewer respondents working in small enterprises reported improvements in ‘lead-time,’ ‘on-time delivery,’ ‘inventory turnover,’ ‘cost per unit,’ and ‘sales per employee’ due to the implementation of Lean than respondents from medium and large enterprises. Small enterprises also indicated a lower need for Lean implementation support from third parties than did medium or large enterprises.

  12. Regulation of Small and Medium-Sized Business Development in Russia: Problems and Solutions

    Directory of Open Access Journals (Sweden)

    Lyudmila Yuryevna Bogachkova

    2015-12-01

    Full Text Available The authors prove that despite the active state policy carried out since the second half of the 2000s and aimed at supporting small and medium-sized business in the Russian Federation, the current level of development of this economic sector is insufficient. The present paper characterizes the modern structure of small and medium-sized business. The authors show that the main problems hindering its growth are conditioned by low market demand, large tax deductions, numerous administrative barriers, lack of funding and state support. On the basis of the official data of Russian Federal State Statistics Service on theresults of annual surveys of entrepreneurs, the authors revealed the factors that prevented innovation situation in the country have stable negative impact on MSB, while the impact of such factors as imperfect legal and regulatory framework, investment risks, low profitability and inadequate state of technological infrastructure is relatively nonsignificant. The authors describe systemwide and resource measures of state regulation of small and medium-sized business. The system-wide measures include preferential access to production facilities and equipment, special tax regimes, administrative control. The measures of resource support to entrepreneurs consist in subsidizing the lease payments and interest rates on loans for the modernization of production; grant support, the establishment of microfinance organizations and guarantee funds, the development of business support infrastructure. The authors describe the forms of these measures implementation in 2013 and the main directions of improving the state regulation of small and medium-sized business, including the reduction of tax burden and facilitation of taxation procedures, the reduction of administrative barriers and ensuring access of small and medium-sized enterprises to government orders and technological infrastructure.

  13. Pen size and parity effects on maternal behaviour of Small-Tail Han sheep.

    Science.gov (United States)

    Lv, S-J; Yang, Y; Dwyer, C M; Li, F-K

    2015-07-01

    The aim of this experiment was to study the effects of pen size and parity on maternal behaviour of twin-bearing Small-Tail Han ewes. A total of 24 ewes were allocated to a 2×2 design (six per pen), with parity (primiparous or multiparous) and pen size (large: 6.0×3.0 m; small: 6.0×1.5 m) as main effects at Linyi University, Shandong Province, China. Behaviour was observed from after parturition until weaning. All ewes were observed for 6 h every 5 days from 0700 to1000 h and from 1400 to 1700 h. Continuous focal animal sampling was used to quantify the duration of maternal behaviours: sucking, grooming and following as well as the frequency of udder accepting, udder refusing and low-pitched bleating. Oestradiol and cortisol concentrations in the faeces (collected in the morning every 5 days) were detected using EIA kits. All lambs were weighed 24 h after parturition and again at weaning at 35 days of age. The small pen size significantly reduced following (Pprimiparous ewes (Pprimiparous ewes (P<0.001), and ewes in small pens had higher faecal cortisol levels compared with ewes in larger pens (P<0.001). As lambs increased in age, the duration of maternal grooming, following and suckling as well as frequency of udder acceptance and low-pitched bleating all declined, and the frequency of udder refusing increased (P<0.001 for all). Ewe parity, but not pen size, affected lamb weight gain during the period of observation (P<0.001). This is the first study to show that pen size, interacting with parity, can affect the expression of maternal behaviour in sheep during lactation. The study is also the first to report on the maternal behaviour of Chinese native sheep breeds (Small-Tail Han sheep), with implications for the production of sheep in China.

  14. Statistical modelling of wildfire size and intensity: a step toward meteorological forecasting of summer extreme fire risk

    Science.gov (United States)

    Hernandez, C.; Keribin, C.; Drobinski, P.; Turquety, S.

    2015-12-01

    In this article we investigate the use of statistical methods for wildfire risk assessment in the Mediterranean Basin using three meteorological covariates, the 2 m temperature anomaly, the 10 m wind speed and the January-June rainfall occurrence anomaly. We focus on two remotely sensed characteristic fire variables, the burnt area (BA) and the fire radiative power (FRP), which are good proxies for fire size and intensity respectively. Using the fire data we determine an adequate parametric distribution function which fits best the logarithm of BA and FRP. We reconstruct the conditional density function of both variables with respect to the chosen meteorological covariates. These conditional density functions for the size and intensity of a single event give information on fire risk and can be used for the estimation of conditional probabilities of exceeding certain thresholds. By analysing these probabilities we find two fire risk regimes different from each other at the 90 % confidence level: a "background" summer fire risk regime and an "extreme" additional fire risk regime, which corresponds to higher probability of occurrence of larger fire size or intensity associated with specific weather conditions. Such a statistical approach may be the ground for a future fire risk alert system.

  15. Growth rates, seed size, and physiology: do small-seeded species really grow faster?

    Science.gov (United States)

    Turnbull, Lindsay A; Paul-Victor, Cloé; Schmid, Bernhard; Purves, Drew W

    2008-05-01

    Relative growth rate (RGR) is currently the most commonly used method for measuring and comparing species' intrinsic growth potential. Comparative studies have, for example, revealed that small-seeded species have higher RGR, leading to the common belief that small-seeded species possess physiological adaptations for rapid growth that would allow them to outgrow large-seeded species, given sufficient time. We show that, because RGR declines as individual plants grow, it is heavily biased by initial size and does not measure the size-corrected growth potential that determines the outcome of competition in the long-term. We develop a daily growth model that includes a simple mechanistic representation of aboveground and belowground growth and its dependency on plant size and environmental factors. Intrinsic growth potential is encapsulated by the size-independent growth coefficient, G. We parameterized the model using repeated-harvest data from 1724 plants of nine species growing in contrasting nutrient and temperature regimes. Using information-theoretic criteria, we found evidence for interspecific differences in only three of nine model parameters: G, aboveground allocation, and frost damage. With other parameters shared between species, the model accurately reproduced above- and belowground biomass trajectories for all nine species in each set of environmental conditions. In contrast to conventional wisdom, the relationship between G and seed size was positive, despite a strong negative correlation between seed size and average RGR, meaning that large-seeded rather than small-seeded species have higher size-corrected growth potential. Further, we found a significant positive correlation between G and frost damage that, according to simulations, causes rank reversals in final biomass under daily temperature changes of +/- 5 degrees C. We recommend the wider use of this new kind of plant growth analysis as a better way of understanding underlying differences in

  16. Small Size at Birth or Abnormal Intrauterine Growth Trajectory: Which Matters More for Child Growth?

    Science.gov (United States)

    Hutcheon, Jennifer A; Jacobsen, Geir W; Kramer, Michael S; Martinussen, Marit; Platt, Robert W

    2016-06-15

    Small size at birth is linked with lifelong adverse health implications. However, small size is only a proxy for the pathological process of interest, intrauterine growth restriction. We examined the extent to which information on intrauterine growth patterns improved prediction of childhood anthropometry, above and beyond birth weight alone. We obtained fetal weights estimated via serial ultrasound for 478 children in the Scandinavian Successive Small-for-Gestational-Age Births Study (1986-1988). Size at birth was classified using birth weight-for-gestational-age z scores and conditional fetal growth z scores (reflecting growth between 25 weeks' gestation and birth) using internal references. Conditional z scores were also expressed as residuals of birth weight z scores. Growth measures were linked with age-5-years anthropometric characteristics using linear regression. In univariable analyses, conditional fetal growth z scores were positively associated with z scores for child height, body mass index, total skinfold thickness, and head circumference (β = 0.24 (95% confidence interval (CI): 0.18, 0.31), β = 0.16 (95% CI: 0.09, 0.23), β = 0.08 (95% CI: 0.01, 0.16), and β = 0.37 (95% CI: 0.22, 0.52), respectively). However, conditional z scores were highly correlated with birth weight z scores (r = 0.9), and residuals explained minimal additional variation in anthropometric factors (null coefficients; adjusted R(2) increases child growth beyond that obtained from absolute size at birth.

  17. Small- and Medium-Sized Commercial Building Monitoring and Controls Needs: A Scoping Study

    Energy Technology Data Exchange (ETDEWEB)

    Katipamula, Srinivas; Underhill, Ronald M.; Goddard, James K.; Taasevigen, Danny J.; Piette, M. A.; Granderson, J.; Brown, Rich E.; Lanzisera, Steven M.; Kuruganti, T.

    2012-10-31

    Buildings consume over 40% of the total energy consumption in the U.S. A significant portion of the energy consumed in buildings is wasted because of the lack of controls or the inability to use existing building automation systems (BASs) properly. Much of the waste occurs because of our inability to manage and controls buildings efficiently. Over 90% of the buildings are either small-size (<5,000 sf) or medium-size (between 5,000 sf and 50,000 sf); these buildings currently do not use BASs to monitor and control their building systems from a central location. According to Commercial Building Energy Consumption Survey (CBECS), about 10% of the buildings in the U.S. use BASs or central controls to manage their building system operations. Buildings that use BASs are typically large (>100,000 sf). Lawrence Berkeley National Laboratory (LBNL), Oak Ridge National Laboratory (ORNL) and Pacific Northwest National Laboratory (PNNL) were asked by the U.S. Department of Energy’s (DOE’s) Building Technologies Program (BTP) to identify monitoring and control needs for small- and medium-sized commercial buildings and recommend possible solutions. This study documents the needs and solutions for small- and medium-sized buildings.

  18. Deformation twinning in small-sized face-centred cubic single crystals: Experiments and modelling

    Science.gov (United States)

    Liang, Z. Y.; Huang, M. X.

    2015-12-01

    Small-sized crystals generally show deformation behaviour distinct from their bulk counterparts. In addition to dislocation slip, deformation twinning in small-sized face-centred cubic (FCC) single crystals has been reported to follow a different mechanism which involves coherent emission of partial dislocations on successive { 111 } planes from free surface. The present work employed a twinning-induced plasticity (TWIP) steel with a low stacking fault energy to systematically investigate the twin evolution in small-sized FCC single crystals. Micrometre-sized single crystal pillars of TWIP steel were fabricated by focus ion beam and then strained to different levels by compression experiments. Detailed transmission electron microscopy characterization was carried out to obtain a quantitative evaluation of the deformation twins, which contribute to most of the plastic strain. Emissions of partial dislocations from free surface (surface sources) and pre-existing perfect dislocations inside the pillar (inner sources) are found as the essential processes for the formation of deformation twins. Accordingly, a physically-based model, which integrates source introduction methods and source activation criterions for partial dislocation emission, is developed to quantitatively predict the twin evolution. The model is able to reproduce the experimental twin evolution, in terms of the total twin formation, the twin morphology and the occurrence of twinning burst.

  19. CONSIDERATIONS REGARDING THE USE OF MODERN MANAGEMENT METHODS IN PLANNING THE MARKETING ACTIVITY WITHIN THE SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Olteanu Valerica

    2012-07-01

    Full Text Available This paper aims to highlight, from a marketing perspective, the manner and conditions in which small and medium-sized enterprises can use modern management methods in planning the marketing activity. Using modern methods of management are particularly important for managers of these organizations and especially for marketers. Thus, the following methods play a significant role within the marketing activitiesn#8217; development for marketing specialists, namely: management by objectives, management by budgets, management by projects, and management by product. The high degree of understanding and using the above methods is, in the current economic environment, one of the determinants of the market success of small and medium-sized enterprises. In the current context, the adoption of the management by objectives is not a facultative option for the small and medium-sized enterprises, but rather a binding one in the context of adopting and practicing an efficient marketing with significant results on the development of marketing programs comprised within them. Similarly to the management by objectives, the use of the management by budgets within the small and medium-sized enterprises has a series of features required by their smaller size, features that should be considered by marketers. Regarding the use of management by projects, this method has to constitute the foundation for the elaboration of marketing programs developed within the small and medium-sized enterprises, thereby allowing shaping an action that can be accompanied by success in achieving the goals comprised within the marketing programs. Finally, the role of the management by product is extremely important in the marketing activity within the small and medium-sized enterprises, especially in the operationalization of concepts such as strategic marketing and tactical marketing. This paper thus outlines from a marketing point of view the main issues aiming at understanding and using

  20. Arthroscopic repair of small and medium-sized bony Bankart lesions.

    Science.gov (United States)

    Kim, Young-Kyu; Cho, Seung-Hyun; Son, Won-Su; Moon, Sung-Hoon

    2014-01-01

    There has been no study about treatment guidelines for arthroscopic repair according to the size of bony Bankart lesions of less than 25% of the glenoid width. To evaluate the results of arthroscopic repair for bony Bankart lesions managed with different repair techniques based on their size. Case series; Level of evidence, 4. Between March 2005 and February 2009, 44 of 52 consecutive patients with bony Bankart lesions with a size of less than 25% of the entire glenoid were managed with an arthroscopic approach. Of those patients, 34 (77%) were available for outcome analysis at a minimum 24 months' follow-up (mean, 34 months; range, 24-60 months). The size of the fragment was measured by computed tomography (CT) and classified as small (lesions were classified as small (small group), and 18 were classified as medium (medium group). For small lesions, capsulolabral repair using suture anchors without excision of the bony fragment was performed. For medium lesions, anatomic reduction and fixation using suture anchors was performed, and the adequacy of reduction was assessed by CT postoperatively. The visual analog scale (VAS) for pain score and modified Rowe score for bony Bankart repair were compared and the postoperative recurrence rate investigated. One patient from the small group (6.3%) and 1 patient without anatomic reduction of the bony fragment in the medium group (5.6%) experienced traumatic redislocations. The mean VAS score improved from 1.7 preoperatively to 0.5 at final follow-up, and the mean Rowe score improved from 59 to 91 (both P Bankart lesions, restoration of capsulolabral soft tissue tension alone may be enough, whereas in medium lesions, the osseous architecture of the glenoid should be reconstructed for more functional improvement and less pain.

  1. Prognostic Factors Affecting Rotator Cuff Healing After Arthroscopic Repair in Small to Medium-sized Tears.

    Science.gov (United States)

    Park, Ji Soon; Park, Hyung Jun; Kim, Sae Hoon; Oh, Joo Han

    2015-10-01

    Small and medium-sized rotator cuff tears usually have good clinical and anatomic outcomes. However, healing failure still occurs in some cases. To evaluate prognostic factors for rotator cuff healing in patients with only small to medium-sized rotator cuff tears. Case-control study; Level of evidence, 3. Data were prospectively collected from 339 patients with small to medium-sized rotator cuff tears who underwent arthroscopic repair by a single surgeon between March 2004 and August 2012 and who underwent magnetic resonance imaging or computed tomographic arthrography at least 1 year after surgery. The mean age of the patients was 59.8 years (range, 39-80 years), and the mean follow-up time was 20.8 months (range, 12-66 months). The functional evaluation included the visual analog scale (VAS) for pain, American Shoulder and Elbow Surgeons score, Constant-Murley score, and Simple Shoulder Test. Postoperative VAS for pain and functional scores improved significantly compared with preoperative values (P infraspinatus muscle, tear size (anteroposterior dimension), and age were significant factors affecting rotator cuff healing (P infraspinatus fatty degeneration correlated with a higher failure rate. The failure rate was also significantly higher in patients with a tear >2 cm in size (34.2%) compared with patients with a tear ≤2 cm (10.6%) (P infraspinatus muscle according to the Goutallier classification could be a reference point for successful healing, and anatomic outcomes might be better if repair is performed before the patient is 69 years old and the tear size exceeds 2 cm. © 2015 The Author(s).

  2. A Survey on Small Size Diodes For Microwave And Millimeter Wave Frequency Region

    Directory of Open Access Journals (Sweden)

    Rahul Ranjan, Prashant Kumar, Neha Singh

    2014-06-01

    Full Text Available This paper attempts to present a collection of microwave and millimetre wave semiconductor diodes. These semiconductor diodes are operates at microwave frequencies and millimetre frequencies. The invention of these semiconductor diodes led to almost complete replacement of vacuum devices which are bulky and large in size. Because of small size a large number of diodes can integrate on a single chip and this arrangement forms very large-scale integrated circuits which led to solid-state replacement on computer switching circuits. This paper surveys characteristics, applications, advantages and disadvantages of microwave and millimetre wave semiconductor devices.

  3. Communication: Kirkwood-Buff integrals in the thermodynamic limit from small-sized molecular dynamics simulations

    Science.gov (United States)

    Cortes-Huerto, R.; Kremer, K.; Potestio, R.

    2016-10-01

    We present an accurate and efficient method to obtain Kirkwood-Buff (KB) integrals in the thermodynamic limit from small-sized molecular dynamics simulations. By introducing finite size effects into integral equations of statistical mechanics, we derive an analytical expression connecting the KB integrals of the bulk system with the fluctuations of the number of molecules in the corresponding closed system. We validate the method by calculating the activity coefficients of aqueous urea mixtures and the KB integrals of Lennard-Jones fluids. Moreover, our results demonstrate how to identify simulation conditions under which computer simulations reach the thermodynamic limit.

  4. Design and construction of small sized pencil probe to measure bio-impedance.

    Science.gov (United States)

    Keshtkar, Ahmad

    2007-11-01

    Currently, bio-impedance measurements are performed with relatively large probes which are not suitable for all in vivo studies. These are typically designed and constructed for different uses, such as for cervical and oesophagus tissues and are too large for many investigations, including those involving the bladder. Therefore, it was decided to design and construct a small sized pencil probe, using a microscope to solder very small wires to a tiny tip (about 2mm in diameter). In addition, different approaches were used to construct, treat, and perform the safety tests and calibration procedure on the probe before taking impedance measurements of the urinary bladder.

  5. Research on Dynamic Distributed Computing System for Small and Medium-Sized Computer Clusters

    Institute of Scientific and Technical Information of China (English)

    Le Kang; Jianliang Xu; Feng Liu

    2012-01-01

      Distributed computing system is a science by which a complex task that need for large amount of computation can be divided into small pieces and calculated by more than one computer,and we can get the final result according to results from each computer.This paper considers a distributed computing system running in the small and medium-sized computer clusters to solve the problem that single computer has a low efficiency,and improve the efficiency of large-scale computing.The experiments show that the system can effectively improve the efficiency and it is a viable program.

  6. Design of an interdisciplinary engineering elective scoped around collaboration with Small Medium Sized enterprises (SME)

    DEFF Research Database (Denmark)

    Christiansen, Nynne Budtz; Ulrich, Mai-Mai; Pontoppidan, Maja Lund

    2014-01-01

    to the European economy comes from the SME’s and around half of all employees work in micro or small businesses with less than 50 employees5. At the same time the barriers for university collaboration with SMEs are somewhat steeper than working with larger organizations6. The paper will focus on the SME...... of a compulsory 10 ECTS element with focus on interdisciplinary and industry collaboration for all Bachelors of Engineering at The Technical University of Denmark in 2016. As collaboration partner the elective has chosen to work with small and medium sized enterprises (SME) as more than half of the value added...

  7. Confirmation of Small Dynamical and Stellar Masses for Extreme Emission Line Galaxies at z~2

    CERN Document Server

    Maseda, Michael V; da Cunha, Elisabete; Rix, Hans-Walter; Pacifici, Camilla; Momcheva, Ivelina; Brammer, Gabriel B; Franx, Marijn; van Dokkum, Pieter; Bell, Eric F; Fumagalli, Mattia; Grogin, Norman A; Kocevski, Dale D; Koekemoer, Anton M; Lundgren, Britt F; Marchesini, Danilo; Nelson, Erica J; Patel, Shannon G; Skelton, Rosalind E; Straughn, Amber N; Trump, Jonathan R; Weiner, Benjamin J; Whitaker, Katherine E; Wuyts, Stijn

    2013-01-01

    Spectroscopic observations from the Large Binocular Telescope and the Very Large Telescope reveal kinematically narrow lines (~50 km/s) for a sample of 14 Extreme Emission Line Galaxies (EELGs) at redshifts 1.4 1. The stellar mass formed in this vigorous starburst phase represents a large fraction of the total (dynamical) mass, without a significantly massive underlying population of older stars. The occurrence of such intense events in shallow potentials strongly suggests that supernova-driven winds must be of critical importance in the subsequent evolution of these systems.

  8. Novel π-type vortex in a nanoscale extreme type-II superconductor: Induced by quantum-size effect

    Science.gov (United States)

    Huang, Haiyan; Liu, Qing; Zhang, Wenhui; Chen, Yajiang

    2016-11-01

    By numerically solving the Bogoliubov-de Gennes equations, we report a novel π-type vortex state whose order parameter near the core undergoes an extraordinary π-phase change for a quantum-confined extreme type-II s-wave superconductor. Its supercurrent behaves as the cube of the radial coordinate near the core, and its local density of states spectrum exhibits a significant negative-shifted zero-bias peak. Such π-type vortex state is induced by quantum-size effect, and can survive thermal smearing at temperatures up to a critical value Tτ. The Anderson's approximation indicates that the π-type vortex may remain stable under sufficiently week magnetic field in the case less deep in the type-II limit. Moreover, we find that its appearance is governed by the sample size and kFξ0 with kF the Fermi wave number and ξ0 the zero-temperature coherence length. Similar effects may be expected in quantum-confined ultracold superfluid Fermi gasses, or even high-Tc superconductors with proper kFξ0 value.

  9. The Importance Of Angel Investors In Financing The Growth Of Small And Medium Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Veland Ramadani

    2012-07-01

    Full Text Available Angel investors are very important for small and medium sized enterprises because they provide more than money. They are hands-on investors and contribute their skills, expertise, knowledge and contacts in the businesses they invest in. They are wealthy persons with great business experience. They are willing to invest and offer their wealth and knowledge to owners of small and medium sized enterprises and to entrepreneurs to start or develop their businesses. One of the attributes of angel investors is that they like to remain anonymus. Due to this attribute, a lot of ideas can not be accomplished. To eliminate this, many countries establish angel investor syndicates (groups and networks. These syndicates (groups and networks facilitate the process of matching entrepreneurs and angel investors.

  10. Synthesis and characterization of small size fluorescent LEEH caped blue emission ZnTe quantum dots

    Directory of Open Access Journals (Sweden)

    Patnaik Sumanta Kumar

    2017-04-01

    Full Text Available We report here for the first time the synthesis of LEEH caped very small size (2 nm ZnTe quantum dots at low temperature (less than 100 °C using a simple chemical route. The effects of aging and stirring time on the absorption spectra of the quantum dots were investigated. The synthesized nanocrystal (NC was characterized by PL, TEM, XRD and the formation of very small size quantum dots having FCC structure was confirmed. Further, blue emission from the prepared sample was observed during exposure to monochromatic UV radiation. ZnTe NCs obtained in this study were found to be more stable compared to those presented in literature reports. ZnTe NCs may be considered as a new material in place of CdTe for optoelectronics devices.

  11. Parity and litter size effects on maternal behavior of Small Tail Han sheep in China.

    Science.gov (United States)

    Lv, Shen-Jin; Yang, Yan; Li, Fu-Kuan

    2016-03-01

    The effects of parity and litter size on maternal behavior of Small Tail Han sheep was investigated at Linyi University, China. Sixty-eight ewes were observed from parturition to weaning. Continuous focal animal sampling was used to quantify the duration of maternal behaviors. Ewe feces were collected every 2 days and estradiol concentration was measured with an enzyme immunoassay kit. All lambs were weighed 24 h after parturition and again at 35 days of age. Parity increased sucking, following, grooming, low-pitched bleat, head-up and udder-refusal behavior and decreased aggressive behavior (P primiparous ewes at birth (P primiparous ewes. Parity and litter size may have effects on maternal behavior during lactation. Ewes that have 2-3 lambs may be more suitable for production of Small Tail Han sheep in China.

  12. Low Temperature Characteristics of FBG Temperature Sensors with Small-size Packaging

    Institute of Scientific and Technical Information of China (English)

    GUO Ming-jin; JIANG De-sheng

    2006-01-01

    Two small-size package methods, thin stainless steel tube based package method and plating gold based package method for fiber Bragg grating(FBG) temperature sensors, are designed. The characteristics of the FBG temperature sensors in the environment temperature between 203K and 243K are investigated. The wavelengths of the FBG temperature sensors as a function of the temperature are examined experimentally. The experiment results of the two different small-size package sensors in identical conditions are compared with each other. The transmission spectrum of the sensors is analyzed at the temperature of 273K and 213K. The temperature sensitive factors of the sensors are derived analytically and are verified by experiments. Linear fitting to the wavelength-temperature curve is carried out.

  13. Resilient campuses: leveraging resources among small- and moderate-sized institutions of higher education.

    Science.gov (United States)

    Green, Rebekah

    2014-01-01

    Universities and colleges provide students with an opportunity to grow personally and professionally through a structured series of learning experiences. Yet disasters can interrupt traditional place-based education and prove to be intractable policy problems. The challenges of developing robust plans and drilling them extensively are most pronounced among smaller public colleges and universities. This article describes how three small- to moderate-sized higher education institutions formed a consortium to better prepare for emergencies, despite limited resources. Together the institutions built common templates, hired joint staff, and created a suit of joint exercises appropriate for their small size and campus-specific needs. In the process, they shared unique perspectives that improved resilience across the institutions.

  14. THE RELATIONSHIP MARKETING APPLICATION IN SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    SABOU FELICIA

    2016-12-01

    Full Text Available The paper presents the importance of relationship marketing, the communication between customers and romanian small and medium-sized enterprises, analyzing also how are investigated and resolved the complaints received from the customers. In the paper, I made a study through I analyzed if the small and medium-sized enterprises undertake investigations about the reasons which they have lost customers. The study was conducted during january - february 2016, the main research methods used in the study were observation, documentation, analysis and market survey. Also, I chose the study questionnaire as research tool. From this study resulted that 79,31% of companies surveyed, were concerned and investigated the reasons they lost customers. Customer satisfaction is very important to business success, so it is recommended that companies must pay attention to the customers reactions and customers dissatisfaction consequences.

  15. A Sustainable Financing Credit Rating Model for China’s Small- and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Yu Cao

    2014-01-01

    Full Text Available This paper builds a sustainable financing credit rating index system for small- and medium-sized enterprises in China from the perspective of sustainability. Then, a quantitative model for credit rating evaluation based on our index system is proposed by using fuzzy analytic hierarchy process (FAHP, which has the advantage of considering both quantitative and qualitative factors. Our numerical example shows that the index system is effective and practical. Our system improves the existing credit rating system to a certain extent. The evaluation method proposed can play an important guiding role for China's small- and medium-sized enterprises in the current transformation age. In particular, interested stakeholders can use this model to evaluate the investment risk of companies, especially with a focus on sustainability.

  16. The role of independent intermediaries. The case of small and medium-sized exporters

    DEFF Research Database (Denmark)

    Madsen, Tage Koed; Moen, Øystein; Hammervold, Randi

    2012-01-01

    The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control and parti......The article examines how small and medium-sized exporters collaborate with intermediaries in foreign markets by studying the level of control, i.e. the delegation of decisions rights and task solution. It goes one step further than previous research, since it examines degrees of control...... export firms are analysed by a structural equation modelling approach. The article provides empirical evidence that managers keep control of decision making to an extent that may have a negative impact on export performance. The empirical study indicates that firms should participate more in task...

  17. The Role of Branding in Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Franc Vidic

    2013-12-01

    Full Text Available The purpose of this article is to show the relationship between branding and brand management in small and medium-sized enterprises (SMEs. Traditionally, branding was associated with large and global corporations. However, we often forget that small and medium-sized enterprises also deal with their own names (brands in their own way. The study identified four types of businesses, regardless of their association with brands. We named these four types, as follows: Ignorant; User; Low-Cost Producer; and Differentiation Producer. If the first two types (i.e. Ignorant and User differ primarily in the extent to which they use simple branding activities, and are used mainly in the local market where the enterprises tend to operate, we found that the last two types (i.e. low-cost producers and differentiation producers design their branding strategies in accordance with their generic strategies and mode of growth.

  18. Batched Triangular Dense Linear Algebra Kernels for Very Small Matrix Sizes on GPUs

    KAUST Repository

    Charara, Ali

    2017-03-06

    Batched dense linear algebra kernels are becoming ubiquitous in scientific applications, ranging from tensor contractions in deep learning to data compression in hierarchical low-rank matrix approximation. Within a single API call, these kernels are capable of simultaneously launching up to thousands of similar matrix computations, removing the expensive overhead of multiple API calls while increasing the occupancy of the underlying hardware. A challenge is that for the existing hardware landscape (x86, GPUs, etc.), only a subset of the required batched operations is implemented by the vendors, with limited support for very small problem sizes. We describe the design and performance of a new class of batched triangular dense linear algebra kernels on very small data sizes using single and multiple GPUs. By deploying two-sided recursive formulations, stressing the register usage, maintaining data locality, reducing threads synchronization and fusing successive kernel calls, the new batched kernels outperform existing state-of-the-art implementations.

  19. Pulsed Laser Ablation-Induced Green Synthesis of TiO2 Nanoparticles and Application of Novel Small Angle X-Ray Scattering Technique for Nanoparticle Size and Size Distribution Analysis

    Science.gov (United States)

    Singh, Amandeep; Vihinen, Jorma; Frankberg, Erkka; Hyvärinen, Leo; Honkanen, Mari; Levänen, Erkki

    2016-10-01

    This paper aims to introduce small angle X-ray scattering (SAXS) as a promising technique for measuring size and size distribution of TiO2 nanoparticles. In this manuscript, pulsed laser ablation in liquids (PLAL) has been demonstrated as a quick and simple technique for synthesizing TiO2 nanoparticles directly into deionized water as a suspension from titanium targets. Spherical TiO2 nanoparticles with diameters in the range 4-35 nm were observed with transmission electron microscopy (TEM). X-ray diffraction (XRD) showed highly crystalline nanoparticles that comprised of two main photoactive phases of TiO2: anatase and rutile. However, presence of minor amounts of brookite was also reported. The traditional methods for nanoparticle size and size distribution analysis such as electron microscopy-based methods are time-consuming. In this study, we have proposed and validated SAXS as a promising method for characterization of laser-ablated TiO2 nanoparticles for their size and size distribution by comparing SAXS- and TEM-measured nanoparticle size and size distribution. SAXS- and TEM-measured size distributions closely followed each other for each sample, and size distributions in both showed maxima at the same nanoparticle size. The SAXS-measured nanoparticle diameters were slightly larger than the respective diameters measured by TEM. This was because SAXS measures an agglomerate consisting of several particles as one big particle which slightly increased the mean diameter. TEM- and SAXS-measured mean diameters when plotted together showed similar trend in the variation in the size as the laser power was changed which along with extremely similar size distributions for TEM and SAXS validated the application of SAXS for size distribution measurement of the synthesized TiO2 nanoparticles.

  20. Pulsed Laser Ablation-Induced Green Synthesis of TiO2 Nanoparticles and Application of Novel Small Angle X-Ray Scattering Technique for Nanoparticle Size and Size Distribution Analysis.

    Science.gov (United States)

    Singh, Amandeep; Vihinen, Jorma; Frankberg, Erkka; Hyvärinen, Leo; Honkanen, Mari; Levänen, Erkki

    2016-12-01

    This paper aims to introduce small angle X-ray scattering (SAXS) as a promising technique for measuring size and size distribution of TiO2 nanoparticles. In this manuscript, pulsed laser ablation in liquids (PLAL) has been demonstrated as a quick and simple technique for synthesizing TiO2 nanoparticles directly into deionized water as a suspension from titanium targets. Spherical TiO2 nanoparticles with diameters in the range 4-35 nm were observed with transmission electron microscopy (TEM). X-ray diffraction (XRD) showed highly crystalline nanoparticles that comprised of two main photoactive phases of TiO2: anatase and rutile. However, presence of minor amounts of brookite was also reported. The traditional methods for nanoparticle size and size distribution analysis such as electron microscopy-based methods are time-consuming. In this study, we have proposed and validated SAXS as a promising method for characterization of laser-ablated TiO2 nanoparticles for their size and size distribution by comparing SAXS- and TEM-measured nanoparticle size and size distribution. SAXS- and TEM-measured size distributions closely followed each other for each sample, and size distributions in both showed maxima at the same nanoparticle size. The SAXS-measured nanoparticle diameters were slightly larger than the respective diameters measured by TEM. This was because SAXS measures an agglomerate consisting of several particles as one big particle which slightly increased the mean diameter. TEM- and SAXS-measured mean diameters when plotted together showed similar trend in the variation in the size as the laser power was changed which along with extremely similar size distributions for TEM and SAXS validated the application of SAXS for size distribution measurement of the synthesized TiO2 nanoparticles.

  1. The economic and social impacts of site accidents on the small and medium sized construction companies in Nigeria

    OpenAIRE

    Okorie, V.N.; Aigbavboa, C.O.

    2016-01-01

    Abstract: Small and medium sized contractors represent the large number of construction companies in Nigeria. They play an important role in the construction industry. However, site fatalities and injuries cases among the small and medium sized construction companies still remain the most health and safety (H&S) issues around the world. This study seeks to examine the economic and social impacts of site accidents on the small and medium sized construction companies in Nigeria. Questionnaire s...

  2. Small and medium sized enterprise marketing to foreign consumers in Seoul, South Korea

    OpenAIRE

    David A. English

    2015-01-01

    A qualitative case study was used to examine the experiences and perceptions of foreigners during interactions with small- and medium-sized enterprises in the Seoul Metropolitan Area. Two constructs, intercultural communications and consumer language, were used to identify difficulties that foreigners experienced during service encounters. In-depth interviews were conducted with 10 participants based on a purposive sampling frame of 62 foreign professors. The transcripts were entered into MAX...

  3. Case Study of Loaned Employee Utilization in Small & Medium Sized Company (Article)

    OpenAIRE

    那須, 一貴

    2012-01-01

     It is essential to hire skillful workers for small and medium sized company to realize sustainable growth and solve insufficiency of talented person. Utilization of loaned skillful employee from large company is one of the solutions for this issue. Such loaned employee can bring not only technical knowledge that has been developed through long working experience but also personal connections to the host company. But loaned employee faces difficulties under the new working environment because...

  4. Modelling of the costs of decision support for small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Viera Tomišová

    2017-01-01

    Full Text Available The support of decision-making activities in small and medium-sized enterprises (SME has its specific features. When suggesting steps for the implementation of decision-support tools in the enterprise, we identified two main ways of decision-making support based on the data analysis: ERP (Enterprise Resource Planning without BI (Business Intelligence and ERP with BI. In our contribution, we present costs models of both mentioned decision support systems and their practical interpretation.

  5. THE ROLE OF ENTREPRENEURSIHP IN PROMOTING SMALL AND MEDIUM - SIZED ENTERPRISES IN AGRO-BUSINESS

    OpenAIRE

    Dalibor Paniæ

    2014-01-01

    Contemporary markets that are distinguished by high degree of instability have prompted the necessity for correction of development models in all economies that are market-orientated and aspiring to be competitive on a global level. As a response to the challenge, many countries have ’turned’ to the sector of small and medium-size companies that have the necessary degree of business flexibility and adaptability in response to external influences. The fundamental development resource of the „s...

  6. Factors preceding CRM readiness in small- and medium-sized tourism enterprises

    OpenAIRE

    Dinesh Vallabh; Laetitia Radder; Danie Venter

    2015-01-01

    Orientation: Customer relationship management (CRM) is important to organisations striving for competitive advantage through building relationships with their customers.Research purpose: This study identified the factors preceding CRM and assessed selected South African small- and medium-sized tourism enterprises’ (SMTEs) readiness for CRM.Motivation: CRM is likely to enhance SMTEs’ competitiveness. However, successful adoption and implementation of CRM is unlikely unless the organisation is ...

  7. Based on the AHP Small and Medium-Sized Enterprise Supply Chain Supplier Evaluation Research

    Directory of Open Access Journals (Sweden)

    Xianwu Hu

    2013-05-01

    Full Text Available In this study, we have a research of the small and medium-sized enterprise supply chain supplier based on the AHP. For supply chain management issues in the supplier evaluation establishes the evaluation index system and then uses AHP decide the weight of each evaluation index. Moreover, it uses Linear Weighting Method to study supplier performance from perspective of quantitative research and gives the measurement process. In our empirical research, the applied method is scientific and feasible.

  8. BPM Adoption in Small and Medium-sized Companies in Bavaria

    OpenAIRE

    Braunnagel, Daniel; Falk, Thomas; Wehner, Benjamin; Leist, Susanne

    2016-01-01

    Small and medium sized (SMEs) companies are a pillar of the Bavarian economy. With business process management (BPM) providing an important competitive advantage in the globalized economy, the adap-tion of BPM by SMEs has societal relevance. However, the reasons why, or why not, SMEs implement BPM measures are still not fully understood. Previous research addressed this topic either breadthwise as surveys or in depth as case studies, and thus only has a limited perspective. Therefore, in our ...

  9. Work organization and job quality of small and medium-sized enterprises (SMEs) in Japan

    OpenAIRE

    サトウ, ヨシオ

    1995-01-01

    During the last three decades of economic growth in Japan, gaps existing between large and small firms in terms of wages, benefits, etc. have grown smaller and less significant. The amount and quality of human resources available will become more limited after the size of the Japanese population peaks somewhere around the year 2010. Satisfaction expressed by both employers and employees at Japanese SMEs is now better than it was in the past, being accentuated by growing popularity of new mana...

  10. Size selective recognition of small esters by a negative allosteric hemicarcerand

    OpenAIRE

    Holger Staats; Arne Lützen

    2010-01-01

    A bis(resorcinarene) substituted 2,2′-bipyridine was found to bind weakly to small esters like ethyl acetate whereas more bulky esters were not recognized by this hemicarcerand. This size selective molecular recognition could be controlled by a negative cooperative allosteric effect: coordination of a triscarbonyl rhenium chloride fragment to the bipyridine causes a conformational rearrangement that orientates the resorcinarene moieties in different directions so that they cannot act co...

  11. European Health Claims for Small and Medium-Sized Companies – Utopian Dream or Future Reality?

    OpenAIRE

    Sonja Brandenburger; Marc Birringer

    2015-01-01

    Background: In December 2007, the European Regulation (EC) 1924/2006 on nutrition and health claims came into force. The European Union wanted to regulate the use of health claims on products. An online survey was carried out to evaluate the situation, particularly of small and medium-sized companies, dealing with the new regulation. Methods: The online survey on health claims was conducted with 16 enterprises. To underline the findings a SWOT (Strength, Weaknesses, Opportunities, Thr...

  12. Cooperative Strategies: evaluating network strategy management of small and medium-sized enterprises

    OpenAIRE

    Bortolaso,Ingridi; Verschoore,Jorge Renato; Antunes Júnior,José Antônio Valle

    2012-01-01

    Network formation aiming the development of cooperation among small and medium-sized companies has received increasing interest from the organizational field. Recent studies have been devoted to understand the management of those networks, deepening the collective aspects of the structure, the coordination, and the processes, among others. This article lies within the context of network strategy management progress and tries to understand how cooperative strategies are developed and executed....

  13. European Health Claims for Small and Medium-Sized Companies – Utopian Dream or Future Reality?

    Directory of Open Access Journals (Sweden)

    Sonja Brandenburger

    2015-02-01

    Full Text Available Background: In December 2007, the European Regulation (EC 1924/2006 on nutrition and health claims came into force. The European Union wanted to regulate the use of health claims on products. An online survey was carried out to evaluate the situation, particularly of small and medium-sized companies, dealing with the new regulation. Methods: The online survey on health claims was conducted with 16 enterprises. To underline the findings a SWOT (Strength, Weaknesses, Opportunities, Threats analysis was made of the nutrition and health claims regulation regarding small and medium-sized companies in the European food and drink market. Results: The findings of this study indicated that the European Union did a step in the right direction. Most companies defined the decent competition, the simplified trade within the inner-European market, and the consumer protection as positive aspects. The biggest threat is seen in false investment conditioned by the limited research and development budgets, especially of small and medium-sized enterprises, and the cost intensive scientific evaluation to reach an authorized health claim. Conclusions: Overall, there are several strengths and opportunities speaking for SMEs and health claims in the near future. The most promising ones are the publishing of the new European Union Register of Nutrition and Health Claims and the learning effects that will occur. The biggest threat is, and will remain to be, false investment and the possible loss of a lot of money. Nevertheless, health claims for small and medium-sized enterprises will inevitably be the future to keep the European food and drink market competitive.

  14. Small-for-size syndrome in adult-to-adult living-related liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Salvatore; Gruttadauria; Duilio; Pagano; Angelo; Luca; Bruno; Gridelli

    2010-01-01

    Small-for-size syndrome (SFSS) in adult-to-adult living-related donor liver transplantation (LRLT) remains the greatest limiting factor for the expansion of segmental liver transplantation from either cadaveric or living donors. Portal hyperperfusion, venous pathology, and the arterial buffer response signif icantly contribute to clinical and histopathological manifestations of SFSS. Here, we review the technical aspects of surgical and radiological procedures developed to treat SFSS in LRLT, along with the...

  15. Construction and Performance of Small-Sized Coated Conductor Pancake Coils for Surgical Applications

    Science.gov (United States)

    Ge, Y.; Lewin, R.; Cahill, R.; Mortensen, N.; Jones, H.

    With a view to applying small-sized superconducting coils for magnetic manipulation in surgery, three pancake coils have been built with commercially available (RE)BCO coated conductor using different impregnation methods and tested in liquid nitrogen and liquid helium. This paper presents the design and construction procedures of these pancake coils and subsequent test results including transport current characteristics in background fields are discussed.

  16. Use of sales and operations planning in small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Michał Adamczak

    2013-03-01

    Full Text Available Background: Increasing competitiveness in the market, customer expectations related to the shortening of the deadlines and the reduction of prices of products and services force companies to improve the efficiency of internal processes. The integration of planning process is one of possible ways to achieve this aim. The integration of planning processes by the use of SOP model (Sales and Operations Planning is a method to implement this idea. The study allowed to identify ways to implement the process of sales and operations planning in small and medium-sized enterprises. Material and methods: The study was conducted in companies from different industries. The research method was in-depth interviews conducted with managers of companies or persons occupying management positions in the organizational process of implementing sales and operations planning. Results: During the survey, 10 companies were asked about the use of sales and operations planning, its elements and organizational aspects of its development, by the company. Conclusions: The use of sales and operations plan is closely dependent on the size of the company and its localization in the supply chain. Small enterprises are not interested in the integration of the planning process due to the small scale of operations and the centralization of decision-making process. Medium-sized enterprises, due to the increased complexity of the processes of planning, see the benefits of their integration in the SOP model.

  17. The Creation of Small and Medium-Sized Sport Enterprises and the Environmental Factors Affecting It

    Directory of Open Access Journals (Sweden)

    Seyed Morteza Azimzadeh

    2013-05-01

    Full Text Available Small and medium-sized enterprises are very basic solutions for the development of a country; therefore, it is important to understand the factors involved in their creation. Hence, this study sought to examine the relationship between environmental factors and creation of Small and medium-sized sport enterprises. The research population was small and medium-sized sport enterprises (1500 companies; their owners / managers were selected as the research sample (n = 258 by simple random sampling. Data were gathered using environmental factors (α=0.77 and enterprises creation qualification (α=0.81 questionnaires. Descriptive and inferential statistics (Pearson correlation coefficient, Kolmogrof - Smirnov test, and multivariate regression analysis with SPSS16 software was used for data analysis. The results showed that in addition to positive and significant relationship with business, environmental factors could predict 6% of the creation variance; Also, except for the political dimension, all environmental aspects established a significant relationship with enterprise creation( p<0.01. Regression analysis showed that of environmental dimensions, economics and technology dimensions could explain 7 percent of Sports enterprise creation variance. According to path analysis method, this prediction ability is presented in a model. The findings suggested a diminished role of environment and its dimensions in explaining the process of SMEs creation.

  18. Consultation for Small-Sized Penis in the Egyptian Males: A Case Control Study.

    Science.gov (United States)

    Salama, Nader

    2016-05-01

    This study aimed to report penile dimensions in adult Egyptian males consulting for small-sized penis (SSP) and describe their demographics and andrological profile. A case control study was designed through retrospective data analysis of patients (n = 239) seeking advice for SSP and a control group (n = 59). This included sociodemographics, other andrological complaints, and penile dimensions (pendulous length [PL], penopubic or total length [TL], and circumference [CF]) at flaccid and erect states and the size of the prepubic fatty pad. The results reported that most patients were single, students, and smokers and had not completed a university education. Several patients reported falsely premature ejaculation (PE), penile curvature (PC), and small-sized testes. Most penile dimensions of the patients (mean, cm) were significantly lower than those of the controls, whether in flaccid (PL: 7.4 vs. 8.05, p = .008; CF: 8.7 vs. 8.98, p = .026) or erect state (PL: 11.8 vs. 13, p = .000; TL: 14.2 vs. 15, p = .000; CF: 11.3 vs. 11.8, p = .003). However, no patient presented with a pendulous penile length <4 cm in flaccid or <7 cm in erect state. In conclusion, Egyptian men consulting for SSP did not have true small organs, but their penile dimensions were slightly smaller than those of men without such complaint. The proper sexual education program is highly advisable in these situations to avoid the myths and misconceptions about sexuality.

  19. [Health management in small and medium-sized enterprises: results of a representative survey].

    Science.gov (United States)

    Zelfel, R C; Alles, T; Weber, A

    2011-08-01

    The prevalence of workplace health promotion in small and medium-sized enterprises (SME) in Germany as well as age management were investigated. Representative data were collected by computer assisted telephone interviews in 1 441 SME (1-250 employees) in 7 regions of Germany. One-third of the SME have a system of health promotion. Disability management is known only in one third of the enterprises, another third of them knew the legal obligations. About half of the enterprises have a system to collect data about health-related absenteeism in business. Effects caused by the demographic change in Germany are feared by nearly 50% of the enterprises, but only 20% have taken action against it. The implementation of work health promotion is higher in enterprises with more employees. The study shows that workplace health promotion (WHP) in German small and medium-sized enterprises is not yet installed to a wide extent. The smaller the enterprises the less WHP is found. The results are verified by similar studies. Small and medium-sized enterprises have a need for consultation in cases of illness or health prevention. But there is not yet an organised structure available for getting advice. The study is the basis for a national project "Gesunde Arbeit", which will establish these consulting structures. © Georg Thieme Verlag KG Stuttgart · New York.

  20. UNICS - An Unified Instrument Control System for Small/Medium Sized Astronomical Observatories

    CERN Document Server

    Srivastava, Mudit K; Burse, Mahesh P; Chordia, Pravin A; Chillal, Kalpesh S; Mestry, Vilas B; Das, Hillol K; Kohok, Abhay A

    2009-01-01

    Although the astronomy community is witnessing an era of large telescopes, smaller and medium sized telescopes still maintain their utility being larger in numbers. In order to obtain better scientific outputs it is necessary to incorporate modern and advanced technologies to the back-end instruments and to their interfaces with the telescopes through various control processes. However often tight financial constraints on the smaller and medium size observatories limit the scope and utility of these systems. Most of the time for every new development on the telescope the back-end control systems are required to be built from scratch leading to high costs and efforts. Therefore a simple, low cost control system for small and medium size observatory needs to be developed to minimize the cost and efforts while going for the expansion of the observatory. Here we report on the development of a modern, multipurpose instrument control system UNICS (Unified Instrument Control System) to integrate the controls of vari...

  1. Small Angle Neutron Scattering Study of Nano Sized Precipitates in Ferrous Alloys.

    Science.gov (United States)

    Han, Young-Soo; Park, Duck-Gun; Kobayashi, Satoru

    2015-11-01

    Nano-sized precipitates in a Fe-1 wt% Cu alloy were studied by SANS (Small Angle Neutron Scattering). The SANS experiments were performed with the 40 m SANS instrument at HANARO. Due to the ferromagnetic nature of the ferrous alloys, a horizontal magnetic field of 1 Tesla was applied during the SANS experiment. The nano-sized Cu precipitates were quantitatively analyzed by SANS in the Fe-1 wt% Cu alloy. The size of the precipitates increased from 2 nm to 4 nm with increasing aging time from 20 min. to 1800 min. at 753 K. The measured A-ratio obtained from SANS data increased from 2.2 to 6.6 with increasing aging time. It is surmised that Cu clusters containing a large amount of Fe are initiated at the early stage of aging and the Fe content in the Cu precipitate decreases with increasing aging time and eventually an almost pure BCC Cu precipitate is formed.

  2. Synthesis and characterization of mesoporous ZnS with narrow size distribution of small pores

    Science.gov (United States)

    Nistor, L. C.; Mateescu, C. D.; Birjega, R.; Nistor, S. V.

    2008-08-01

    Pure, nanocrystalline cubic ZnS forming a stable mesoporous structure was synthesized at room temperature by a non-toxic surfactant-assisted liquid liquid reaction, in the 9.5 10.5 pH range of values. The appearance of an X-ray diffraction (XRD) peak in the region of very small angles (˜ 2°) reveals the presence of a porous material with a narrow pore size distribution, but with an irregular arrangement of the pores, a so-called worm hole or sponge-like material. The analysis of the wide angle XRD diffractograms shows the building blocks to be ZnS nanocrystals with cubic structure and average diameter of 2 nm. Transmission electron microscopy (TEM) investigations confirm the XRD results; ZnS crystallites of 2.5 nm with cubic (blende) structure are the building blocks of the pore walls with pore sizes from 1.9 to 2.5 nm, and a broader size distribution for samples with smaller pores. Textural measurements (N2 adsorption desorption isotherms) confirm the presence of mesoporous ZnS with a narrow range of small pore sizes. The relatively lower surface area of around 100 m2/g is attributed to some remaining organic molecules, which are filling the smallest pores. Their presence, confirmed by IR spectroscopy, seems to be responsible for the high stability of the resulting mesoporous ZnS as well.

  3. Born small, die young: Intrinsic, size-selective mortality in marine larval fish

    KAUST Repository

    Garrido, S.

    2015-11-24

    Mortality during the early stages is a major cause of the natural variations in the size and recruitment strength of marine fish populations. In this study, the relation between the size-at-hatch and early survival was assessed using laboratory experiments and on field-caught larvae of the European sardine (Sardina pilchardus). Larval size-at-hatch was not related to the egg size but was significantly, positively related to the diameter of the otolith-at-hatch. Otolith diameter-at-hatch was also significantly correlated with survival-at-age in fed and unfed larvae in the laboratory. For sardine larvae collected in the Bay of Biscay during the spring of 2008, otolith radius-at-hatch was also significantly related to viability. Larval mortality has frequently been related to adverse environmental conditions and intrinsic factors affecting feeding ability and vulnerability to predators. Our study offers evidence indicating that a significant portion of fish mortality occurs during the endogenous (yolk) and mixed (yolk /prey) feeding period in the absence of predators, revealing that marine fish with high fecundity, such as small pelagics, can spawn a relatively large amount of eggs resulting in small larvae with no chances to survive. Our findings help to better understand the mass mortalities occurring at early stages of marine fish.

  4. Enhanced Z-LDA for Small Sample Size Training in Brain-Computer Interface Systems

    Directory of Open Access Journals (Sweden)

    Dongrui Gao

    2015-01-01

    Full Text Available Background. Usually the training set of online brain-computer interface (BCI experiment is small. For the small training set, it lacks enough information to deeply train the classifier, resulting in the poor classification performance during online testing. Methods. In this paper, on the basis of Z-LDA, we further calculate the classification probability of Z-LDA and then use it to select the reliable samples from the testing set to enlarge the training set, aiming to mine the additional information from testing set to adjust the biased classification boundary obtained from the small training set. The proposed approach is an extension of previous Z-LDA and is named enhanced Z-LDA (EZ-LDA. Results. We evaluated the classification performance of LDA, Z-LDA, and EZ-LDA on simulation and real BCI datasets with different sizes of training samples, and classification results showed EZ-LDA achieved the best classification performance. Conclusions. EZ-LDA is promising to deal with the small sample size training problem usually existing in online BCI system.

  5. Experimental Laboratory Research and Evaluation of Periodic Operation Small Size Bioreactors

    Directory of Open Access Journals (Sweden)

    Vitalij Kolodynskij

    2016-10-01

    Full Text Available The investigation device – small size periodic operation bioreactors, which are developed for the production of biogas from different organic, vegetable waste. The device operates by maintaining optimum operating temperature and oxygen concentration required for anaerobic treatment process inside the bioreactor. Under favorable conditions, organic substance is being degradated because of anaerobic processess, colonies of microorganisms grow, and methane bacteria produce CH4 – useful flammable gases, which can be used as natural gas analogue. The gas is stored in special tanks of gas – gas holders. A study was implemented by analizing five different loads, according to the mixing ratio of vegetables (potatoes and chicken manure waste. The quality and quantity of biogas was analized as well. It was found that the highest concentration of methane (67.8% was achieved by using a load consisting only of chicken manure, but after evaluation of biogas yield, it was found that the best result (according to the quantity of biogas, a high concentration of CH4 and time of load degradation is achieved using chicken manure and potato waste mix (relatively 70 and 30%. Mesophilic process temperature during the experiment was 33–35 °C, and oxygen concentration – 0.0–0.1%. After research implementation there will be an opportunity to create small size periodic operation bioreactors, which can be used in small farms or private houses, where the small amount of organic waste and manure are formed.

  6. AIUB Efforts to Survey, Track, and Characterize Small-Size Objects at High Altitudes

    Science.gov (United States)

    Schildknecht, T.; Früh, C.; Herzog, J.; Hinze, A.; Vananti, A.

    2010-09-01

    Since more than a decade the Astronomical Institute of the University of Bern (AIUB) is investigating the small-size space debris environment in high-altitude orbit regions. Originally the efforts concentrated on statistical optical surveys with the primary goal to derive fluxes as input data for statistical environment models. It became, however, obvious that important characteristics of the debris population could not be determined by this technique. The sparse surveys did not yield orbital elements for the debris objects, and it was very difficult to assess the total number of objects for a given region. One essential task of the space debris research is to find and understand the sources of debris, which in turn will enable to devise efficient mitigation measures - a prerequisite for the sustainable use of outer space. In order to understand the nature and eventually the origin of small-size debris objects, observations allowing to derive orbital parameters and physical characteristics like size, shape and material are required. This paper discusses the AIUB activities to build-up and maintain an orbit catalogue of small-size debris. AIUB uses its dedicated 0.3m robotic telescope ZimSMART-2 to constantly survey the GEO, the GTO and the MEO region. The data from this telescope is fused with observations from AIUB's 1-meter ZIMLAT telescope and ESA's 1-meter telescope in Tenerife and shared with international partners. The resulting catalogue of orbital elements enables physical characterization of the debris objects trough photometry, light curve and reflectance spectroscopy observations.

  7. Off like a shot: scaling of ballistic tongue projection reveals extremely high performance in small chameleons.

    Science.gov (United States)

    Anderson, Christopher V

    2016-01-04

    Stretching elastic tissues and using their recoil to power movement allows organisms to release energy more rapidly than by muscle contraction directly, thus amplifying power output. Chameleons employ such a mechanism to ballistically project their tongue up to two body lengths, achieving power outputs nearly three times greater than those possible via muscle contraction. Additionally, small organisms tend to be capable of greater performance than larger species performing similar movements. To test the hypothesis that small chameleon species outperform larger species during ballistic tongue projection, performance was examined during feeding among 20 chameleon species in nine genera. This revealed that small species project their tongues proportionately further than large species, achieving projection distances of 2.5 body lengths. Furthermore, feedings with peak accelerations of 2,590 m s(-2), or 264 g, and peak power output values of 14,040 W kg(-1) are reported. These values represent the highest accelerations and power outputs reported for any amniote movement, highlighting the previously underestimated performance capability of the family. These findings show that examining movements in smaller animals may expose movements harbouring cryptic power amplification mechanisms and illustrate how varying metabolic demands may help drive morphological evolution.

  8. Preparation of Small Particle Sized ZnAl-Hydrotalcite-Like Compounds by Ultrasonic Crystallization

    Institute of Scientific and Technical Information of China (English)

    Xianmei Xie; Xiurong Ren; Jinping Li; Xiaojun Hu; Zhizhong Wang

    2006-01-01

    Ultrasonic technology has been intensively studied recently due to its special features. In this paper, an ultrasonic crystallization method was introduced for the preparation of ZnAl-Hydrotalcite-Like compounds (ZnAl-HTLcs). Samples with high crystallinity, small particle size and narrow particle size distribution were obtained and fully characterized using conventional techniques of XRD, FT-IR and TG-DTA. The results prove that both ultrasonic frequency and ultrasonic power have effects on the sizes of the product particles. By varying the ultrasonic power from 250 W to 88 W, with the ultrasonic frequency fixed at 59 kHz, the median particle size of the samples increased from 0.37μm to 0.82μm. By altering the hydrothermal treatment time from 1 h to 5 h at 110 ℃, the median particle size of ZnAl-HTLcs synthesized via ultrasonic crystallization increased from 0.88 μm to 1.11 μm.

  9. Relationship between tumor size and disease stage in non-small cell lung cancer

    Directory of Open Access Journals (Sweden)

    Yang Fu

    2010-09-01

    Full Text Available Abstract Background Whether tumor size and stage distribution are correlated remains controversial. The objective is to assess the relationship between tumor size and disease stage distribution in non-small cell lung cancer (NSCLC. Methods We conducted a retrospective analysis of 917 cases of NSCLC that were resected in the Cancer Hospital of Fudan University and Shanghai Sixth Hospital between January 2000 and February 2009. Tumor sizes were grouped into five categories: ≤20 mm, 21 to 30 mm, 31 to 50 mm, 51 to 70 mm and ≥71 mm. Results Age and tumor size affected stage distribution: patients 60 years or older had a higher percentage of N0M0 disease than patients younger than 60 years (61.67% vs. 44.85%, p Conclusions There is a statistically significant relationship between tumor size and distribution of disease stage of primary NSCLC tumors: the smaller the tumor, the more likely the disease is N0M0 status.

  10. SU-E-T-611: Effective Treatment Volume of the Small Size IORT Applicators

    Energy Technology Data Exchange (ETDEWEB)

    Krechetov, A.S. [Intraop Medical Corp, Sunnyvale, CA (United States); ASK Physics, Mountain View, CA (United States); Goer, D.A. [Intraop Medical Corp, Sunnyvale, CA (United States)

    2014-06-01

    Purpose Mobile electron linear accelerators are gaining more attention recently, providing a lower cost and simpler way to perform intraoperative treatment. However, the simplicity of the treatment process does not eliminate the need for proper attention to the technical aspects of the treatment. One of the potential pitfalls is incorrect selection of the appropriate applicator size to adequately cover the tumor bed to the prescription dose. When treating tumor beds in the pelvis, the largest applicator that fits into the pelvis is usually selected as there is concern about microscopic extension of the disease along the sidewalls of the pelvis. But when treating early stage breast tumors, there is a natural tendency to select an applicator as small as possible so as not to jeopardize cosmesis. Methods This investigation questions how much of the typical breast treatment volume gets adequate exposure and what is the correct strategy in selecting the proper applicator size. Actual data from isodose scans were analyzed. Results We found that typical treatment dose prescriptions can cover as much as 80% and as little as 20% of the nominal treatment volume depending on the applicator size and energy of the beam and whether the dose is prescribed to the 80 or 90% isodose level. Treatment volume is defined as a cylinder with diameter equal to applicator and height equal to the corresponding D80 or D90 depth. Conclusion If mobile linear accelerators are used, there can be significant amount of “cold volume” depending on the applicator size and this should be taken into account when selecting the applicator that is needed. Using too small of an applicator could result in significant under-dosing to the tissue at risk. Long-term clinical data demonstrates that selecting an adequate field size results in good ontological control as well as excellent cosmesis. Intraop Medical Corp was providing facilities and equipment for this research.

  11. Condensation on surface energy gradient shifts drop size distribution toward small drops.

    Science.gov (United States)

    Macner, Ashley M; Daniel, Susan; Steen, Paul H

    2014-02-25

    During dropwise condensation from vapor onto a cooled surface, distributions of drops evolve by nucleation, growth, and coalescence. Drop surface coverage dictates the heat transfer characteristics and depends on both drop size and number of drops present on the surface at any given time. Thus, manipulating drop distributions is crucial to maximizing heat transfer. On earth, manipulation is achieved with gravity. However, in applications with small length scales or in low gravity environments, other methods of removal, such as a surface energy gradient, are required. This study examines how chemical modification of a cooled surface affects drop growth and coalescence, which in turn influences how a population of drops evolves. Steam is condensed onto a horizontally oriented surface that has been treated by silanization to deliver either a spatially uniform contact angle (hydrophilic, hydrophobic) or a continuous radial gradient of contact angles (hydrophobic to hydrophilic). The time evolution of number density and associated drop size distributions are measured. For a uniform surface, the shape of the drop size distribution is unique and can be used to identify the progress of condensation. In contrast, the drop size distribution for a gradient surface, relative to a uniform surface, shifts toward a population of small drops. The frequent sweeping of drops truncates maturation of the first generation of large drops and locks the distribution shape at the initial distribution. The absence of a shape change indicates that dropwise condensation has reached a steady state. Previous reports of heat transfer enhancement on chemical gradient surfaces can be explained by this shift toward smaller drops, from which the high heat transfer coefficients in dropwise condensation are attributed to. Terrestrial applications using gravity as the primary removal mechanism also stand to benefit from inclusion of gradient surfaces because the critical threshold size required for

  12. SMALL SAMPLE SIZE IN 2X2 CROSS OVER DESIGNS: CONDITIONS OF DETERMINATION

    Directory of Open Access Journals (Sweden)

    B SOLEYMANI

    2001-09-01

    Full Text Available Introduction. Determination of small sample size in some clinical trials is a matter of importance. In cross-over studies which are one types of clinical trials, the matter is more significant. In this article, the conditions in which determination of small sample size in cross-over studies are possible were considered, and the effect of deviation from normality on the matter has been shown. Methods. The present study has been done on such 2x2 cross-over studies that variable of interest is quantitative one and is measurable by ratio or interval scale. The method of consideration is based on use of variable and sample mean"s distributions, central limit theorem, method of sample size determination in two groups, and cumulant or moment generating function. Results. In normal variables or transferable to normal variables, there is no restricting factors other than significant level and power of the test for determination of sample size, but in the case of non-normal variables, it should be determined such large that guarantee the normality of sample mean"s distribution. Discussion. In such cross over studies that because of existence of theoretical base, few samples can be computed, one should not do it without taking applied worth of results into consideration. While determining sample size, in addition to variance, it is necessary to consider distribution of variable, particularly through its skewness and kurtosis coefficients. the more deviation from normality, the more need of samples. Since in medical studies most of the continuous variables are closed to normal distribution, a few number of samples often seems to be adequate for convergence of sample mean to normal distribution.

  13. Extreme patterns of variance in small populations: placing limits on human Y-chromosome diversity through time in the Vanuatu Archipelago.

    Science.gov (United States)

    Cox, M

    2007-05-01

    Small populations are dominated by unique patterns of variance, largely characterized by rapid drift of allele frequencies. Although the variance components of genetic datasets have long been recognized, most population genetic studies still treat all sampling locations equally despite differences in sampling and effective population sizes. Because excluding the effects of variance can lead to significant biases in historical reconstruction, variance components should be incorporated explicitly into population genetic analyses. The possible magnitude of variance effects in small populations is illustrated here via a case study of Y-chromosome haplogroup diversity in the Vanuatu Archipelago. Deme-based modelling is used to simulate allele frequencies through time, and conservative confidence bounds are placed on the accumulation of stochastic variance effects, including diachronic genetic drift and contemporary sampling error. When the information content of the dataset has been ascertained, demographic models with parameters falling outside the confidence bounds of the variance components can then be accepted with some statistical confidence. Here I emphasize how aspects of the demographic history of a population can be disentangled from stochastic variance effects, and I illustrate the extreme roles of genetic drift and sampling error for many small human population datasets.

  14. High-speed atomic force microscopy for large scan sizes using small cantilevers

    Science.gov (United States)

    Braunsmann, Christoph; Schäffer, Tilman E.

    2010-06-01

    We present a high-speed atomic force microscope that exhibits a number of practical advantages over previous designs. Its central component is a high-speed scanner with a maximum scan size of 23 µm × 23 µm and a conveniently large sample stage area (6.5 mm × 6.5 mm). In combination with small cantilevers, image rates of up to 46 images s - 1 in air and 13 images s - 1 in liquid are reached under z-feedback control. By large scan size imaging of collagen fibrils in air, sample velocities of 8.8 mm s - 1 in the xy-direction and 11 mm s - 1 in the z-direction are reached. To provide optimized imaging conditions for both large and small scan sizes, a modular scanner design allows easily exchanging the x- and y-piezos. The scanner is therefore also suited for investigations on the molecular and atomic scale, which is demonstrated by imaging the step dynamics of a calcite surface during dissolution and the hexagonal lattice of a mica surface in liquid.

  15. The Single Mirror Small Sized Telescope For The Cherenkov Telescope Array

    CERN Document Server

    Heller, M; Porcelli, A; Pujadas, I Troyano; Zietara, K; della Volpe, D; Montaruli, T; Cadoux, F; Favre, Y; Aguilar, J A; Christov, A; Prandini, E; Rajda, P; Rameez, M; Bilnik, W; Blocki, J; Bogacz, L; Borkowski, J; Bulik, T; Frankowski, A; Grudzinska, M; Idzkowski, B; Jamrozy, M; Janiak, M; Kasperek, J; Lalik, K; Lyard, E; Mach, E; Mandat, D; Marszalek, A; Miranda, L D Medina; Michalowski, J; Moderski, R; Neronov, A; Niemiec, J; Ostrowski, M; Pasko, P; Pech, M; Schovanek, P; Seweryn, K; Sliusar, V; Skowron, K; Stawarz, L; Stodulska, M; Stodulski, M; Walter, R; Wiecek, M; Zagdanski, A

    2016-01-01

    The Small Size Telescope with Single Mirror (SST-1M) is one of the proposed types of Small Size Telescopes (SST) for the Cherenkov Telescope Array (CTA). About 70 SST telescopes will be part the CTA southern array which will also include Medium Sized Telescopes (MST) in its threshold configuration. Optimized for the detection of gamma rays in the energy range from 5 TeV to 300 TeV, the SST-1M uses a Davies-Cotton optics with a 4 m dish diameter with a field of view of 9 degrees. The Cherenkov light resulting from the interaction of the gamma-rays in the atmosphere is focused onto a 88 cm side-to-side hexagonal photo-detection plane. The latter is composed of 1296 hollow light guides coupled to large area hexagonal silicon photomultipliers (SiPM). The SiPM readout is fully digital readout as for the trigger system. The compact and lightweight design of the SST-1M camera offers very high performance ideal for gamma-ray observation requirement. In this contribution, the concept, design, performance and status of...

  16. Butterfly cartilage tympanoplasty: An alternative approach for management of small- and medium-sized perforations

    Directory of Open Access Journals (Sweden)

    Ashish Kumar Maurya

    2016-01-01

    Full Text Available Objective: To evaluate the efficacy of butterfly cartilage tympanoplasty for small- and medium-sized central perforations and compare it with temporalis fascia tympanoplasty. Materials and Methods: A prospective, comparative study was conducted on 110 patients, divided into two groups. Patients of tubotympanic type of chronic suppurative otitis media with 2–6 mm size perforation were included in the study. Fifty-five patients were operated by temporalis fascia Type I tympanoplasty and rest 55 by butterfly cartilage tympanoplasty (transcanal technique under local anesthesia. Results were compared in terms of pre- and post-operative air-bone gap improvement and success rates. Results: In our study, in terms of outcomes, both techniques had similar results. The success rate was 93.7% in butterfly cartilage tympanoplasty and 96.3% in temporalis fascia group. However, in terms of time taken, butterfly cartilage tympanoplasty took less time (about 30 min than temporalis fascia (about 55 min. Conclusion: Transcanal butterfly cartilage tympanoplasty is a very good alternative in small- and medium-sized perforations for conventional temporalis fascia tympanoplasty as it is simple, takes less time, day care procedure, on table hearing improvement, cosmetically no postoperative scar, no need of post aural preparation, and patient can go home within hours.

  17. Penetration of small and medium sized food companies on foreign markets

    Directory of Open Access Journals (Sweden)

    Ladislav Mura

    2010-01-01

    Full Text Available In the world the interconnection of national economies and internationalization of economic processes occur. In turbulent changing business environment only those companies that understand the current trends in global economy may survive, develop and prosper. Therefore, the issue of internationalization for most companies becomes to be more important and the process of in­ter­na­tio­na­li­za­tion is the way how to stand this increasingly competitive environment. In presented contribution, the attention is paid to issues of internationalization of Slovak food industry enterprises such as their way of business internationalization, percentage share of foreign - trading activities on overall business activity, company evaluation of business internationalization or barriers of foreign markets pe­ne­tra­tion that researched companies have to deal with. Small and medium-sized enterprises (SMEs are the engine of the Slovak economy, generator of development, innovation, growth and they employ more than 60% of employees. Almost all businesses operating in agri-food complex have character of small and medium enterprises. The results of carried research have shown that small and medium-sized companies are considered to be successful in operation on foreign markets in surrounding European countries.

  18. A meta-analysis of different HR-enhancing practices and performance of small and medium sized firms

    NARCIS (Netherlands)

    Rauch, Andreas; Hatak, Isabella

    2016-01-01

    The role of human capital has received considerable attention in research on small and medium sized firms. However, much uncertainty remains as to how practices that enhance human resources (HR) affect the performance of small and medium sized firms, whether some practices have stronger effects than

  19. 75 FR 9431 - Small and Medium-Sized Enterprises: U.S. and EU Export Activities, and Barriers and Opportunities...

    Science.gov (United States)

    2010-03-02

    ... From the Federal Register Online via the Government Publishing Office INTERNATIONAL TRADE COMMISSION Small and Medium-Sized Enterprises: U.S. and EU Export Activities, and Barriers and Opportunities... investigations, investigation No. 332-509, Small and Medium-Sized Enterprises: U.S. and EU Export Activities,...

  20. A meta-analysis of different HR-enhancing practices and performance of small and medium sized firms

    NARCIS (Netherlands)

    Rauch, Andreas; Hatak, Isabella

    2016-01-01

    The role of human capital has received considerable attention in research on small and medium sized firms. However, much uncertainty remains as to how practices that enhance human resources (HR) affect the performance of small and medium sized firms, whether some practices have stronger effects than

  1. 40 CFR 428.50 - Applicability; description of the small-sized general molded, extruded, and fabricated rubber...

    Science.gov (United States)

    2010-07-01

    ... small-sized general molded, extruded, and fabricated rubber plants subcategory. 428.50 Section 428.50... RUBBER MANUFACTURING POINT SOURCE CATEGORY Small-Sized General Molded, Extruded, and Fabricated Rubber... fabricated rubber plants subcategory. The following provisions of this subpart are applicable to...

  2. Requirement analysis to promote small-sized E-waste collection from consumers.

    Science.gov (United States)

    Mishima, Kuniko; Nishimura, Hidekazu

    2016-02-01

    The collection and recycling of small-sized waste electrical and electronic equipment is an emerging problem, since these products contain certain amounts of critical metals and rare earths. Even if the amount is not large, having a few supply routes for such recycled resources could be a good strategy to be competitive in a world of finite resources. The small-sized e-waste sometimes contains personal information, therefore, consumers are often reluctant to put them into recycling bins. In order to promote the recycling of E-waste, collection of used products from the consumer becomes important. Effective methods involving incentives for consumers might be necessary. Without such methods, it will be difficult to achieve the critical amounts necessary for an efficient recycling system. This article focused on used mobile phones among information appliances as the first case study, since it contains relatively large amounts of valuable metals compared with other small-sized waste electrical and electronic equipment and there are a large number of products existing in the market. The article carried out surveys to determine what kind of recycled material collection services are preferred by consumers. The results clarify that incentive or reward money alone is not a driving force for recycling behaviour. The article discusses the types of effective services required to promote recycling behaviour. The article concludes that securing information, transferring data and providing proper information about resources and environment can be an effective tool to encourage a recycling behaviour strategy to promote recycling, plus the potential discount service on purchasing new products associated with the return of recycled mobile phones.

  3. A framework for effective implementation of lean production in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Amine Belhadi

    2016-09-01

    Full Text Available Purpose: The present paper aims at developing an effective framework including all the components necessary for implementing lean production properly in Small and Medium-sized Enterprises. Design/methodology/approach: The paper begins with the review of the main existing framework of lean implementation in order to highlight shortcomings in the literature through a lack of suitable framework for small companies. To overcome this literature gap, data of successful initiatives of lean implementation were collected based on a multiple case study approach. These initiatives has been juxtaposed in order to develop a new, practical and effective framework that includes all the components (process, tools, success factors that are necessary to implement lean in Small and Medium-sized Enterprises. Findings: The proposed framework presents many significant contributions: First, it provides an overcoming for the limitations of the existing frameworks by proposing for consultants, researchers and organizations an effective framework for lean implementation in SMEs that allows SMEs to benefit from competitive advantages  gained by lean. Second, it brings together a set of the more essential and critical elements of lean implementation commonly used by SMEs and derived from the practical experiences of them in lean implementation. Finally, it highlights the successful experiences of small companies in implementing lean programs and then proves that lean can give a relevant results even for SMEs. Research limitations/implications: The proposed framework presents a number of limitations and still evokes extension for further researches: Although it was derived from practical experiences of SMEs, the proposed framework is not supported by practical implementation. On the other hand and even though the elements in the proposed framework from the practical experiences of four SMEs, the identified elements need to be generalized and enriching by conducting

  4. Stochastic spatial disaggregation of extreme precipitation to validate a Regional Climate Model and to evaluate climate change impacts over a small watershed

    Directory of Open Access Journals (Sweden)

    P. Gagnon

    2013-06-01

    Full Text Available Regional Climate Models (RCMs are valuable tools to evaluate impacts of climate change (CC at regional scale. However, as the size of the area of interest decreases, the ability of a RCM to simulate extreme precipitation events decreases due to the spatial resolution. Thus, it is difficult to evaluate whether a RCM bias on localized extreme precipitation is caused by the spatial resolution or by a misrepresentation of the physical processes in the model. Thereby, it is difficult to trust the CC impact projections for localized extreme precipitation. Stochastic spatial disaggregation models can bring the RCM precipitation data at a finer scale and reduce the bias caused by spatial resolution. In addition, disaggregation models can generate an ensemble of outputs, producing an interval of possible values instead of a unique discrete value. The objective of this work is to evaluate whether a stochastic spatial disaggregation model applied on annual maximum daily precipitation: (i enables the validation of a RCM for a period of reference, and (ii modifies the evaluation of CC impacts over a small area. Three simulations of the Canadian RCM (CRCM covering the period 1961–2099 are used over a small watershed (130 km2 located in southern Québec, Canada. The disaggregation model applied is based on Gibbs sampling and accounts for physical properties of the event (wind speed, wind direction, and convective available potential energy (CAPE, leading to realistic spatial distributions of precipitation. The results indicate that disaggregation has a significant impact on the validation. However it does not provide a precise estimate of the simulation bias because of the difference in resolution between disaggregated values (4 km and observations, and because of the underestimation of the spatial variability by the disaggregation model for the most convective events. Nevertheless, disaggregation permits to determine that the simulations used mostly

  5. Characterization and optimization of Silicon Photomultipliers and small size scintillator tiles for future calorimeter applications

    CERN Document Server

    AUTHOR|(CDS)2095312; Horváth, Ákos

    For the active layers of highly granular sampling calorimeters, small scintillator tiles read out by Silicon Photomultipliers (SiPM) can be an interesting and cost effective alternative to silicon sensors. At CERN a test setup was realized for the development of new generations of calorimeters to characterize new types of Silicon Photomultipliers in terms of gain, noise, afterpulses and crosstalk and to study the impact of scintillator wrappings and the tile size on the measured light yield and uniformity. In this thesis work, the experimental setup is described and the steps for commissioning the equipment are discussed. Then, the temperature dependence of the Silicon Photomultiplier response will be investigated, including the dependence of bare Silicon Photomultipliers as well as Silicon Photomultipliers coupled to scintillator tiles. Finally, the tile-photomultiplier response for different tile sizes and coating options will be evaluated. The experimental setup will be extended to allow for the characteri...

  6. Subnanometer Control of Mean Core Size during Mesofluidic Synthesis of Small (D(core) Nanoparticles.

    Science.gov (United States)

    Elliott, Edward W; Haben, Patrick M; Hutchison, James E

    2015-11-03

    A convenient, single-step synthesis is reported that produces ligand-stabilized, water-soluble gold nanoparticles (AuNPs) with subnanometer-level precision of the mean core diameter over a range of 2-9 nm for a series of desired surface chemistries. The synthesis involves the reduction of a Au(III) species with sodium borohydride in the presence of a functionalized alkyl thiosulfate (Bunte salt) to yield thiolate-protected AuNPs. A key advantage of this synthesis is that simply adjusting the pH of the gold salt solution leads to control over the AuNP core size. The speciation of Au(III), and therefore the kinetics for its reduction and the core size produced, depends upon pH. The use of pH as the sole variable to control core size is a more reliable and convenient method than traditional approaches that rely on adjusting the concentrations and ratios of ligand, metal salt, and reducing agent. The average core size increased as the pH was raised for each ligand studied. Because the influence of pH was different for each of the ligands, working curves were plotted for each ligand to identify conditions to synthesize particles with specific, targeted core diameters. Using this approach, reaction conditions can be rapidly optimized using a combination of a mesofluidic reactor and small-angle X-ray scattering (SAXS) size analysis. The use of the mesofluidic reactor was needed to ensure fast mixing given the rapid kinetics for core formation. Using the reactor, it is possible to obtain reproducible sizes across multiple syntheses (size variation) and subnanometer control of the mean core dimensions. The synthetic method demonstrated here provides an attractive alternative to two-step syntheses involving ligand exchange because it is more efficient and eliminates the possibility of nanoparticle core size changes during exchange steps. This approach enables the development of "size ladders" of particles with the same surface chemistry for investigations of structure

  7. Seasonal occurrence of extreme events on example of long-term hydrometeorological observations from small catchment

    Science.gov (United States)

    Kaznowska, Ewa; Hejduk, Agnieszka; Hejduk, Leszek

    2014-05-01

    Periodical occurrence of floods and droughts is one of disadvantageous phenomenon of Polish climate. Forecasting of climate change for Poland in first half of the 21th century indicate a probability of more frequent occurrence of droughts, which will have the consequences in water deficits in significant areas of the country. Runoff characteristics are important indicators of water resources. Long-term observations carried out in small catchments are an important source of informations of water regime. The aim of the study was to analyze trends of occurrence floods and droughts in small, agricultural catchment of Zagożdżonka River, which is one of the few in Poland, with long-term records of rainfall and runoff. The catchment is located in central Poland, Mazovian Lowlands, about 100 km south form Warsaw. The area of the catchment till Płachty Stare station is 82 km2 and 23.4 km2 till Czarna station . The data used for statistical analysis of floods and droughts included 50 years (1963-2012) for Płachty Stare gauging station and the period of 22 years (1991-2012) for Czarna station. Based on daily hydrograph, floods and droughts were identified. In most cases the duration of floods and droughts is short (few days). Long-term floods occur in winter season and long-term drought occur in summer and autumn. In Płachty Stare decreased trend was indicated for number of days with flood discharge and increased trend was found for number of days with droughts. In Czarna gauging station opposite trends were found. Acknowledgment The paper has been prepared with financial support by grants NN 305 1445 40, NN 305 3168 40 both funded by National Science Center

  8. An analytical solution for determination of small contact angles from sessile drops of arbitrary size.

    Science.gov (United States)

    Allen, Jeffrey S

    2003-05-15

    An analytical solution to the capillary equation of Young and Laplace is derived that allows determination of the static contact angle based on the volume of a sessile drop and the wetted area of the substrate. This solution does not require numerical integration to determine the drop profile and accounts for surface deformation due to gravitational effects. Calculation of the static contact angle by this method is remarkably simple and accurate when the contact angle is less than 30 degrees. A natural scaling arises in the solution, which provides indication of when a drop is small enough so as to neglect gravitational influences on the surface shape which, for small contact angles, is generally less than 1 microl. The technique described has the simplicity of the spherical cap approximation but remains accurate for any size of sessile drop.

  9. Current information technology needs of small to medium sized apparel manufacturers and contractors

    Energy Technology Data Exchange (ETDEWEB)

    Wimple, C., LLNL

    1998-04-01

    This report documents recent efforts of the American Textile Partnership (AMTEX{sup TM}) Demand Activated Manufacturing Architecture (DAMA) Project to identify opportunities for cost effective enhanced information technology use by small to medium sized apparel manufacturers and contractors. Background on the AMTEX/DAMA project and objectives for the specific DAMA Small and Medium Enterprise (SME) effort are discussed in this section. The approach used to gather information about current opportunities or needs is outlined in Section 2 Approach, and relevant findings are identified and a brief analysis of the information gathered is presented in Section 3 Findings. Recommendations based on the analysis, are offered in Section 4 Recommendations, and plans are suggested for DAMA follow-on in Section 5 Future Plans. Trip reports for each of the companies visited are contained in Appendix E - Company Trip Reports. These individual reports contain the data upon which the analysis presented in Section 3 Findings is based.

  10. Attitude angle anti-windup control of small size unmanned helicopter

    Science.gov (United States)

    Shao, Taizhou; Long, Haihui; Zhao, Jiankang; Xia, Xuan; Yang, Guang

    2017-01-01

    This paper researches the small-size unmanned helicopter attitude control problem with actuator saturation limit. Traditional approach for this problem is often based on an accurate dynamic model which is complicated and difficult to achieve in engineering. In this paper, we propose an anti-windup PID approach which does not rely on sophicated helicopter dynamic model. The anti-windup PID controller is established by adding a phase-lead compensator to the conventional PID controller. The performance and merits of this proposed controller are exemplified by the simulations between the conventional PID controller and the anti-windup PID controller.

  11. A 10-step safety management framework for construction small and medium-sized enterprises.

    Science.gov (United States)

    Gunduz, Murat; Laitinen, Heikki

    2016-07-20

    It is of great importance to develop an occupational health and safety management system (OHS MS) to form a systemized approach to improve health and safety. It is a known fact that thousands of accidents and injuries occur in the construction industry. Most of these accidents occur in small and medium-sized enterprises (SMEs). This article provides a 10-step user-friendly OHS MS for the construction industry. A quantitative OHS MS indexing method is also introduced in the article. The practical application of the system to real SMEs and its promising results are also presented.

  12. IMPACT OF INNOVATION UPON THE DYNAMICS OF ROMANIAN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    JEANINA CIUREA

    2013-10-01

    Full Text Available Innovation is central to economic growth, as the area in which it develops takes the whole sphere of economic activities: product, process, service, organization, marketing, hence the economic effects they may cause. Creating "innovative enterprises", giving tax cuts to certain periods of time, preferential loans, creating funds 'risk capital' are just some of the measures that European countries which already apply and Romania, willing to encourage innovation. The present paper presents two ways of exposing this issue, using theoretical sources but also real official data concerning the concept of innovation and also the ways of applying it within small and medium sized enterprises.

  13. WAYS TO IMPROVE THE RELIABILITY AND OPERATING LIFE OF SMALL-SIZE ELECTROMAGNETIC VALVE

    Directory of Open Access Journals (Sweden)

    Gennadii Zaionchkovskyi

    2015-04-01

    Full Text Available This article considers the main ways of improving the reliability and durability of small-size electromagnetic valves. Major changes in the technical state of the valve components under dynamic operating loads were revealed using the results of resource tests of two-position valves with polarized electromagnetic actuator. Aneffective way for reducing the dynamic loads has proved to be the introduction of the damping element into the kinematic scheme of the electromagnetic valve actuator. Damping elements efficiency in reducing dynamic loads has been confirmed experimentally.

  14. Amino acid substitution at the Adh locus of Drosophila is facilitated by small population size.

    Science.gov (United States)

    Ohta, T

    1993-01-01

    The number of amino acid replacement substitutions and that of synonymous substitutions are examined by using DNA sequences of the Adh locus of Drosophila. The ratio of replacement to synonymous substitutions is higher in sequence comparisons between species than in polymorphisms within species. The ratio for the between-species comparisons is highest in the Hawaiian group and lowest in the obscura group. These observations suggest that amino acid substitutions are facilitated by small population size. The result is in accord with the nearly neutral theory of molecular evolution. PMID:8506297

  15. Financial Management Challenges In Small And Medium-Sized Enterprises: A Strategic Management Approach

    Directory of Open Access Journals (Sweden)

    Hande Karadag

    2015-02-01

    Full Text Available Abstract :Due to their significant role in creation of new jobs, rise in GDP, entrepreneurship and innovation, small and medium-sized enterprises (SMEs are recognized as the the drivers of socio-economic growth, both in developed and developing economies. In Turkey, 99.9 % of all enterprises fall into SME category. Therefore, the significance of SMEs for Turkish economy and society is much higher in Turkey, compared to other emerging and developed countries. Small and medium-sized companies are faced with a number of challenges whereas the problems arising from “poor financial management” are reported as the major causes of business failures in SMEs. Strategic financial management (SFM which is a research area that has attracted the interest of researchers after 2010, is one of the key managerial areas of SMEs, due to its vital role on the survival, growth and performance of SMEs. The purpose of this paper is to analyze the central role of financial management and identify the financial management challenges and practices that influence the organizational performance in Turkish SMEs, from a strategic management perspective. Within the course of this paper, the importance and challenges of SMEs in Turkey are presented in the first section, while the literature on strategic and financial management in SMEs are reviewed in the second part. In the third section, the recent strategic financial management concept, the implications of strategic financial management practices for SMEs in Turkey and the relationships between strategic financial management practices and SME performance, are discussed. Small and medium sized enterprise finance in Turkey is a developing research area, therefore this paper aims to make a significant contribution to the existing literature by analyzing the major challenges at the conduct of financial management in Turkish SMEs and the influence of strategic financial management practices on the performances of small and

  16. Origin of sample size effect: Stochastic dislocation formation in crystalline metals at small scales

    Science.gov (United States)

    Huang, Guan-Rong; Huang, J. C.; Tsai, W. Y.

    2016-12-01

    In crystalline metals at small scales, the dislocation density will be increased by stochastic events of dislocation network, leading to a universal power law for various material structures. In this work, we develop a model obeyed by a probability distribution of dislocation density to describe the dislocation formation in terms of a chain reaction. The leading order terms of steady-state of probability distribution gives physical and quantitative insight to the scaling exponent n values in the power law of sample size effect. This approach is found to be consistent with experimental n values in a wide range.

  17. Numerical and experimental studies of resonators with reduced resonant frequencies and small electrical sizes

    CERN Document Server

    Hao, T; Edwards, D J; Stevens, C J

    2008-01-01

    Methods on reducing resonant frequencies and electrical sizes of resonators are reported in this paper. Theoreti-cal and numerical analysis has been used and the results for the broadside-coupled resonators from both studies exhibit good agreement. Initial fabrication techniques are proposed and measurement results are compared with simulations. Further high resolution techniques have been envisaged to enhance the performance of the resona-tors. This class of small resonators with low resonant frequencies indicates a variety of applications in the design of microwave devices.

  18. Eco-modernizing small en medium-sized agro-industries in Vietnam

    OpenAIRE

    Pham Hong Nhat

    2007-01-01

    Following ‘Doi Moi’ (Renovation), which started in 1986, the former centrally planned economy in Vietnam is shifting to an economy where production is linked to market demand and consumption. As a result, the nation has been enjoying an unprecedentedly fast economic growth, especially in recent years: 8.4% in 2005 and 8.17% in 2006. The economic renovation also brought an expansion of the private sector, which consists mainly of small- and medium-sized enterprises, SMEs. The reform process ha...

  19. Visual SLAM and Moving-object Detection for a Small-size Humanoid Robot

    Directory of Open Access Journals (Sweden)

    Yin-Tien Wang

    2010-09-01

    Full Text Available In the paper, a novel moving object detection (MOD algorithm is developed and integrated with robot visual Simultaneous Localization and Mapping (vSLAM. The moving object is assumed to be a rigid body and its coordinate system in space is represented by a position vector and a rotation matrix. The MOD algorithm is composed of detection of image features, initialization of image features, and calculation of object coordinates. Experimentation is implemented on a small-size humanoid robot and the results show that the performance of the proposed algorithm is efficient for robot visual SLAM and moving object detection.

  20. Detection of small-size planetary candidates with CoRoT data

    Directory of Open Access Journals (Sweden)

    Moutou C.

    2011-02-01

    Full Text Available With the discovery of CoRoT-7b, the first transiting super-Earth, the CoRoT space mission has shown the capability to detect short-period rocky planets around solar-like stars. By performing a blind test with real CoRoT light curves, we want to establish the detection threshold of small-size planets in CoRoT data. We investigate the main obstacles to the detection of transiting super-Earths in CoRoT data, notably the presence of short-time scale variability and hot pixels.

  1. Small particle size lipid emulsions, satiety and energy intake in lean men.

    Science.gov (United States)

    Chan, Y K; Budgett, S C; MacGibbon, A K; Quek, S Y; Kindleysides, S; Poppitt, S D

    2017-02-01

    Lipid emulsions have been proposed to suppress hunger and food intake. Whilst there is no consensus on optimal structural properties or mechanism of action, small particle size (small-PS) stable emulsions may have greatest efficacy. Fabuless®, a commercial lipid emulsion reported in some studies to decrease energy intake (EI), is a small-PS, 'hard' fat emulsion comprising highly saturated palm oil base (PS, 82nm). To determine whether small-PS dairy lipid emulsions can enhance satiety, firstly, we investigated 2 'soft' fat dairy emulsions generated using dairy and soy emulsifying agents (PS, 114nm and 121nm) and a non-emulsified dairy control. Secondly, we investigated a small-PS palmolein based 'hard' fat emulsion (fractionated palm oil, PS, 104nm) and non-emulsified control. This was a 6 arm, randomized, cross-over study in 18 lean men, with test lipids delivered in a breakfast meal: (i) Fabuless® emulsion (FEM); (ii) dairy emulsion with dairy emulsifier (DEDE); (iii) dairy emulsion with soy lecithin emulsifier (DESE); (iv) dairy control (DCON); (v) palmolein emulsion with dairy emulsifier (PEDE); (vi) palmolein control (PCON). Participants rated postprandial appetite sensations using visual analogue scales (VAS), and ad libitum energy intake (EI) was measured at a lunch meal 3.5h later. Dairy lipid emulsions did not significantly alter satiety ratings or change EI relative to dairy control (DEDE, 4035kJ; DESE, 3904kJ; DCON, 3985kJ; P>0.05) nor did palm oil based emulsion relative to non-emulsified control (PEDE, 3902 kJ; PCON, 3973kJ; P>0.05). There was no evidence that small-PS dairy lipid emulsions or commercial Fabuless altered short-term appetite or food intake in lean adults. Copyright © 2016. Published by Elsevier Inc.

  2. Performance evaluation of a mouse-sized camera for dynamic studies in small animals

    Science.gov (United States)

    Loudos, George; Majewski, Stan; Wojcik, Randy; Weisenberger, Andrew; Sakellios, Nicolas; Nikita, Konstantina; Uzunoglu, Nikolaos; Bouziotis, Penelope; Varvarigou, Alexandra

    2007-02-01

    A mouse sized camera has been built in terms of collaboration between the presenting institutions. The system is used for the performance of dynamic studies in small animals, in order to evaluate novel radiopharmaceuticals. The active area of the detector is approximately 48×96 mm allowing depiction of the entire mouse in a single view. The system is based on two flat-panel Hamamatsu H8500 position sensitive photomultiplier tubes (PSPMT), a pixellated NaI(Tl) scintillator and a copper-beryllium (CuBe) parallel-hole collimator. In this work, the evaluation results of the system are presented, using phantoms and small animals injected with conventional radiophrmaceuticals. Average resolution was ˜1.6 mm on the collimator surface and increased to ˜4.1 mm in 12 cm distance from the detector. The average energy resolution was measured and found to be ˜15.6% for Tc 99m. Results from imaging thin capillaries demonstrated system's high resolution and sensitivity in activity variations was shown. Initial dynamic studies have been carried out in small animals injected with Tc 99m-DTPA and Tc 99m-MDP. The results show system's ability to perform kinetic imaging in small animals.

  3. Operational Risk Assessment and Management in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Viktorija Stasytytė

    2015-07-01

    Full Text Available Modern organizations have raised a need to actively and quickly react to the changes in external business environment, as well as in internal processes considering not only the present situation, but also evaluating possible changes and forecasting the future. Enterprise risk assessment and management, which is strongly related with foreseeing the uncertain future, becomes topical not only scientifically, but also practically seeking to reveal new and unique solutions. Operational risk management in small and medium enterprises, creating the largest part of value added in the whole European Union, demands a separate attention and coordinated decisions and means. The objective of the paper – to analyse the process of enterprise risk management in small and medium-sized enterprises, as well as to propose adequate risk management solutions for these companies. After performing a research, it was found out that small and medium enterprises more than big organizations require a risk management strategy and methodology, need to distinguish activity objectives and events influencing them, and they can efficiently apply a risk portfolio method to manage risk. In small and medium enterprises it is recommended to incorporate a risk management system based on COSO ERM model that can be modified depending on company needs and possibilities, turning it into less formal and structured and easily applicable.

  4. Simplified product value measurement framework for small and medium sized enterprises

    Directory of Open Access Journals (Sweden)

    S Parkash

    2013-09-01

    Full Text Available Background: The emergences of global markets have increased competition worldwide. For Small Medium Sized Enterprises with limited resources to sustain in what is already a very competitive market there is a need for strong and continuously increasing Product Value to reduce business risks and revenue losses and to increase market share and customer satisfaction. To fulfill this need, Product Value Measurement is necessary to characterize the current status and further improvement. It is not easy to obtain the measures about the Product Value because its many features have qualitative characteristics. We need simplified but result oriented systematic framework to measure it while considering the measurement purpose and how to measure and why do it. Methods: How to design this is the main aim of this research paper. In this paper, GQM (Goal-Question-Metric method as a measurement framework is introduced to measure the Product Value for Small Medium Sized Enterprises along with case study to represent that this framework was effective. Results and conclusions: The proposed Model was effective for focusing on the essence of measurement and for avoiding extra excessive data not necessary for doing the effective measurement.

  5. A Small-Sized HTGR System Design for Multiple Heat Applications for Developing Countries

    Directory of Open Access Journals (Sweden)

    Hirofumi Ohashi

    2013-01-01

    Full Text Available Japan Atomic Energy Agency has conducted a conceptual design of a 50 MWt small-sized high temperature gas cooled reactor (HTGR for multiple heat applications, named HTR50S, with the reactor outlet coolant temperature of 750°C and 900°C. It is first-of-a-kind of the commercial plant or a demonstration plant of a small-sized HTGR system to be deployed in developing countries in the 2020s. The design concept of HTR50S is to satisfy the user requirements for multipurpose heat applications such as the district heating and process heat supply based on the steam turbine system and the demonstration of the power generation by helium gas turbine and the hydrogen production using the water splitting iodine-sulfur process, to upgrade its performance compared to that of HTTR without significant R&D utilizing the knowledge obtained by the HTTR design and operation, and to fulfill the high level of safety by utilizing the inherent features of HTGR and a passive decay heat removal system. The evaluation of technical feasibility shows that all design targets were satisfied by the design of each system and the preliminary safety analysis. This paper describes the conceptual design and the preliminary safety analysis of HTR50S.

  6. Barriers to development of the innovation potential in the small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Jakub Tabas

    2011-01-01

    Full Text Available It is a common fact, that innovations are the necessary prerequisite of economic development. With regard to the gradual globalization of the world economy, it is obvious that the strategic objectives of every country are directed to own economic wealth which is lead especially by the small and medium-sized enterprises. Due to the fact that these business entities are creating the most of economic growth of every country, the necessity of research, support and development of their innovation potential is obvious. The last and also the least that one could starve for is the building up the barriers to innovativeness of domestic companies, and to decrease competitiveness of the country.In the paper, the authors are focused on the determination of barriers to innovation potential of small and medium-sized enterprises. For this reason, the secondary research of recent studies on innovation barriers has been elaborated. Subsequently, the primary research has been realized on the statistical sample of 173 SMEs. Based on the data analyses, the authors have proved four statistical interactions between innovation potential and factors which stand as barriers to innovation potential development. This paper is based on the confrontation of outcomes of primary research with the secondary research on world-wide perceived barriers to innovations. Data obtained from the primary research had mostly the qualitative and categorical character. Due to this fact, especially Chi-square Test, normalized Pearson coefficient of contingence and Chuprov’s coefficient have been applied.

  7. Determinants of Supply and Demand for Trade Credit by Micro, Small and Medium-Sized Enterprises

    Directory of Open Access Journals (Sweden)

    Claudinê Jordão de Carvalho

    2015-08-01

    Full Text Available This article investigates the determinant factors of supply and demand for trade credit by micro, small and medium-sized enterprises (MSMEs, using data collected in a survey of managers from 481 firms in 32 cities in the states of São Paulo and Minas Gerais (Brazil between 2008 and 2010. The multivariate relationship model proposed here is grounded in trade credit, agency and transaction costs theories. This study is based on a technique known as path analysis that uses a system of simple regressions estimated by simultaneous equations. The main results show the following: (i trade credit and short-term bank loans are supplementary (and not substitute sources of funds for MSMEs, which demonstrates that trade credit can be used by financial institutions as an indicator of the creditworthiness of the company; (ii the proportion of credit sales, the days sales outstanding measure and sales growth are positively related to the amount of trade credit demanded, which suggests that trade credit is transferred along the supply chain; and (iii the supply of trade credit is positively related to the importance that management ascribes to both internal capital and bank credit, which illustrates the strategic use of the supply of trade credit to increase sales. These results have important implications for companies' managers, financial institutions and the government agencies responsible for formulating policies that support and promote the development of small and medium-sized enterprises.

  8. Evolution Balancing of the Small-Sized Wheel Loader Assembly Line

    Directory of Open Access Journals (Sweden)

    Rongshen Lai

    2015-01-01

    Full Text Available Assembly line balancing not only directly determines production efficiency but also influences precision and quality of key assemblies or even the overall performance of final products. Driven by market demand and development of science and technology, product family must evolve constantly, which necessitates frequent adjustment and rebalancing of product family assembly line (PFAL. In order to maintain production efficiency, improve assembly quality and precision, and reduce costs for adjustment, the evolution balancing problem of PFAL for small-sized wheel loader is solved in this paper. Firstly, the evolution balancing model of PFAL is put forward. Then, with minimizing the number of workstations, the in-station and between-station load indexes and adjustment costs, and maximizing relevancy between activities as optimization objectives, meanwhile regarding product platform planning, modularity design and the critical chain technology in concurrent engineering as constraint conditions, the evolution balancing problem of PFAL is optimized using improved genetic algorithm (IGA. Finally, the whole analysis procedure is demonstrated by the small-sized wheel loader PFAL case study and the effectiveness of the proposed method is verified.

  9. A small-size pulsed lidar designed for obstacles detection in natural underwater environment

    Science.gov (United States)

    Zeng, Xianjiang; Xia, Min; Cheng, Zao; Li, Lei; Chen, Junyao; Du, Peng; Yang, Kecheng

    2015-10-01

    In this paper, we designed a pint-sized underwater pulsed lidar system for underwater obstacles detection based on a 532nm Nd-YAG pulsed laser as a source and a Hamamatsu photomultiplier tube (PMT) as a detector. In order to acquire the location of the obstacles, an algorithm was devised to handle the echo signal. Through this algorithm, the background noise was suppressed and the accurate range information of the target was obtained. A high-capacity lithium battery was employed to support this lidar system operating as long as eight hours continuously. To ensure our lidar system working steady in the natural underwater environment, a stable waterproof housing was designed for the system which has good water-tightness at 40m depth underwater. This system is small, compact and hand-held. An experiment was conducted in laboratory which proof that the system can achieve target detection within 25m. At last, this lidar system was tested in natural underwater environment of Fuxian Lake in Yunnan Province. There are lots of organic particles and other impurity particles in Fuxian Lake and the attenuation coefficient of the lake is about 0.67m-1. The results showed that this small-size lidar system was able to catch sight of the target within 20 meters and perform smoothly in the natural underwater environment.

  10. Techno-economical method for the capacity sizing of a small hydropower plant

    Energy Technology Data Exchange (ETDEWEB)

    Santolin, A., E-mail: alberto.santolin@unipd.i [Department of Mechanical Engineering, University of Padova, Via Venezia 1, 35131 Padova (Italy); Cavazzini, G., E-mail: giovanna.cavazzini@unipd.i [Department of Mechanical Engineering, University of Padova, Via Venezia 1, 35131 Padova (Italy); Pavesi, G., E-mail: giorgio.pavesi@unipd.i [Department of Mechanical Engineering, University of Padova, Via Venezia 1, 35131 Padova (Italy); Ardizzon, G., E-mail: guido.ardizzon@unipd.i [Department of Mechanical Engineering, University of Padova, Via Venezia 1, 35131 Padova (Italy); Rossetti, A., E-mail: antonio.rossetti@unipd.i [Department of Mechanical Engineering, University of Padova, Via Venezia 1, 35131 Padova (Italy)

    2011-07-15

    Research highlights: {yields} A method for the capacity sizing of a small hydropower plant was developed. {yields} The model was developed on the basis of the flow duration curve of the site. {yields} Seven techno-economical parameters were considered in the analysis. {yields} The influence of the design operating conditions on the parameters was analysed. {yields} The method allowed a proper choice of the optimal design operating conditions. -- Abstract: This paper presents a method for the capacity sizing of a small hydropower plant on the basis of techno-economical analyses of the flow duration curve. Seven technical and economical parameters were considered: the turbine type, the turbine dimensions, the annual energy production, the maximum installation height to avoid cavitation inception, the machine cost, the Net Present Value (NPV) and the Internal Rate of Return (IRR). A proper model was proposed to study the effects of the design operating conditions on these parameters. The model, applied to the flow duration curve, allowed to analyse the feasibility, the profitability and the performance of the plant in the available flowing range of the site. To verify the effectiveness of the proposed method, three sites having different flow duration curves were analysed.

  11. The Relative Efficiency of Container Terminals in Small and Medium-Sized Ports in China

    Directory of Open Access Journals (Sweden)

    Zi-Yao Ding

    2015-06-01

    Full Text Available The promotion of domestic consumption in China will gradually ramp up the small and medium-sized port container industry, and this will require greater port efficiency and an updated development strategy. The aim of this paper is to evaluate operational and productivity efficiency change in 21 coastal small and medium sized-port container terminals in China. The first step was carried out using data envelopment analysis (DEA and the Malmquist productivity index (MPI, and the factors affecting productivity efficiency change were then estimated and quantified using Tobit regression. The empirical results indicate that the most efficient terminals are the Rizhao and Lianyungang port terminals. Furthermore, the terminals that hold a share of more than 50% of Chinese state-owned shipping line show the highest increase in productivity efficiency change. Lastly, the results indicate manpower structure; Chinese state-owned shipping line shareholding; registered capital; and shipping routes have positive effect and the factor, number of terminal operators, have a negative correlation.

  12. In situ detection of small-size insect pests sampled on traps using multifractal analysis

    Science.gov (United States)

    Xia, Chunlei; Lee, Jang-Myung; Li, Yan; Chung, Bu-Keun; Chon, Tae-Soo

    2012-02-01

    We introduce a multifractal analysis for detecting the small-size pest (e.g., whitefly) images from a sticky trap in situ. An automatic attraction system is utilized for collecting pests from greenhouse plants. We applied multifractal analysis to segment action of whitefly images based on the local singularity and global image characteristics. According to the theory of multifractal dimension, the candidate blobs of whiteflies are initially defined from the sticky-trap image. Two schemes, fixed thresholding and regional minima obtainment, were utilized for feature extraction of candidate whitefly image areas. The experiment was conducted with the field images in a greenhouse. Detection results were compared with other adaptive segmentation algorithms. Values of F measuring precision and recall score were higher for the proposed multifractal analysis (96.5%) compared with conventional methods such as Watershed (92.2%) and Otsu (73.1%). The true positive rate of multifractal analysis was 94.3% and the false positive rate minimal level at 1.3%. Detection performance was further tested via human observation. The degree of scattering between manual and automatic counting was remarkably higher with multifractal analysis (R2=0.992) compared with Watershed (R2=0.895) and Otsu (R2=0.353), ensuring overall detection of the small-size pests is most feasible with multifractal analysis in field conditions.

  13. An end pumped all internal reflection small-sized slab picosecond laser amplifier

    Science.gov (United States)

    Chen, Junchi; Peng, Yujie; Su, Hongpeng; Leng, Yuxin

    2017-05-01

    An end pumped all internal reflection small-sized slab picosecond laser system amplifier is proposed and demonstrated based on the common Nd:YAG crystal. A cylinder lens is introduced to pre-compensate for the one-dimensional thermal effect caused by the high power pumping laser. The maximum output powers of 6.6 and 6.3 W are obtained at the absorbed pumping power of 25 W without and with a cylinder mirror, and the corresponding optical conversion efficiencies are about 10.4% and 9.3% respectively. The measured M 2 factors along the slow and fast axes are 1.71 and 2.47 respectively. The instability of the maximum output laser is below 0.8% (RMS) within measuring time up to 15 min. It is demonstrated that the all internal reflection slab can support long enough optical gain distance to realize the signal laser amplification for the newly developed crystal even with small size and low doped concentration.

  14. Fast synthesis and bioconjugation of (68) Ga core-doped extremely small iron oxide nanoparticles for PET/MR imaging.

    Science.gov (United States)

    Pellico, Juan; Ruiz-Cabello, Jesús; Saiz-Alía, Marina; Del Rosario, Gilberto; Caja, Sergio; Montoya, María; Fernández de Manuel, Laura; Morales, M Puerto; Gutiérrez, Lucia; Galiana, Beatriz; Enríquez, Jose A; Herranz, Fernando

    2016-05-01

    Combination of complementary imaging techniques, like hybrid PET/MRI, allows protocols to be developed that exploit the best features of both. In order to get the best of these combinations the use of dual probes is highly desirable. On this sense the combination of biocompatible iron oxide nanoparticles and 68Ga isotope is a powerful development for the new generation of hybrid systems and multimodality approaches. Our objective was the synthesis and application of a chelator-free 68Ga-iron oxide nanotracer with improved stability, radiolabeling yield and in vivo performance in dual PET/MRI. We carried out the core doping of iron oxide nanoparticles, without the use of any chelator, by a microwave-driven protocol. The synthesis allowed the production of extremely small (2.5 nm) 68Ga core-doped iron oxide nanoparticles. The microwave approach allowed an extremely fast synthesis with a 90% radiolabeling yield and T1 contrast in MRI. With the same microwave approach the nano-radiotracer was functionalized in a fast and efficient way. We finally evaluated these dual targeting nanoparticles in an angiogenesis murine model by PET/MR imaging. Copyright © 2016 John Wiley & Sons, Ltd. Copyright © 2016 John Wiley & Sons, Ltd.

  15. SU-E-T-299: Small Fields Profiles Correction Through Detectors Spatial Response Functions and Field Size Dependence Analysis

    Energy Technology Data Exchange (ETDEWEB)

    Filipuzzi, M; Garrigo, E; Venencia, C [Instituto de Radioterapia - Fundacion Marie Curie, Cordoba, Cordoba (Spain); Germanier, A [CEPROCOR, Cordoba, Cordoba (Spain)

    2014-06-01

    Purpose: To calculate the spatial response function of various radiation detectors, to evaluate the dependence on the field size and to analyze the small fields profiles corrections by deconvolution techniques. Methods: Crossline profiles were measured on a Novalis Tx 6MV beam with a HDMLC. The configuration setup was SSD=100cm and depth=5cm. Five fields were studied (200×200mm2,100×100mm2, 20×20mm2, 10×10mm2and 5×5mm2) and measured were made with passive detectors (EBT3 radiochromic films and TLD700 thermoluminescent detectors), ionization chambers (PTW30013, PTW31003, CC04 and PTW31016) and diodes (PTW60012 and IBA SFD). The results of passive detectors were adopted as the actual beam profile. To calculate the detectors kernels, modeled by Gaussian functions, an iterative process based on a least squares criterion was used. The deconvolutions of the measured profiles were calculated with the Richardson-Lucy method. Results: The profiles of the passive detectors corresponded with a difference in the penumbra less than 0.1mm. Both diodes resolve the profiles with an overestimation of the penumbra smaller than 0.2mm. For the other detectors, response functions were calculated and resulted in Gaussian functions with a standard deviation approximate to the radius of the detector in study (with a variation less than 3%). The corrected profiles resolve the penumbra with less than 1% error. Major discrepancies were observed for cases in extreme conditions (PTW31003 and 5×5mm2 field size). Conclusion: This work concludes that the response function of a radiation detector is independent on the field size, even for small radiation beams. The profiles correction, using deconvolution techniques and response functions of standard deviation equal to the radius of the detector, gives penumbra values with less than 1% difference to the real profile. The implementation of this technique allows estimating the real profile, freeing from the effects of the detector used for the

  16. State-of-art methodology of marine natural products chemistry: structure determination with extremely small sample amounts.

    Science.gov (United States)

    Murata, M; Oishi, T; Yoshida, M

    2006-01-01

    Structure elucidation studies on natural products are reviewed emphasizing extremely small sample amounts. Previous studies on insect pheromones, periplanones, and bean-originating kairomones, glycinoeclepins, are described briefly. Recent examples are selected from marine natural products such as ciguatoxin, dolastatin-3, and aurisides. A more detailed description is given of a sperm-activating and attracting factor (SAAF), which may be the smallest sample amount used in the structure elucidation of novel non-peptidic natural products. SAAF was isolated from the eggs of the ascidian, Ciona intestinalis, and its structure was deduced with only approximately 4 microg (6 nmol) of sample. Based upon the proposed structure, two epimers were synthesized from chenodeoxycholic acid in 17 steps, leading to the identification of SAAF as a novel sterol sulfate.

  17. THE RELATIONSHIP BETWEEN SMALL AND MEDIUM-SIZED ENTERPRISES, TOURISM AND ECONOMIC DEVELOPMENT

    Directory of Open Access Journals (Sweden)

    Tatjana Dimoska

    2015-01-01

    Full Text Available Tourism is the world’s largest industry and makes a major contribution to the economies of most developed and developing countries. Tourism as an important socio-economical phenomenon is characterized with distinctly largeness and dynamic development that results with many positive direct as well as indirect economical effects. That is a measure for increasing of possibilities of encouragement of the total economical development through tourism development. Tourism generates income from consumption of goods and services by tourists as well as taxes on businesses in the tourism industry, provides employment in services related to tourism, but also creates jobs in the tertiary sector, generates growth of primary and secondary sectors of the industry as result of multiplicative effect. In this context especially are important small and medium tourism enterprises which dominate in the tourism destinations according to their number, originating a variety of benefits for the tourism destinations by providing direct contact with tourists and by encouraging tourist for spending in a local community. The aim of this paper is to point out the importance of small and medium –sized enterprises in general and especially in the field of tourism for increasing economic development in the national economy with particular reference on the territory of the Republic of Macedonia. In this paper, first will be analyzed the term small and medium - sized enterprises in general and then will be explained their application in the field of tourism with highlighting of their strategic advantages for the tourism destinations and overall economic development of the entire national economy. Finally, will be analyzed the role played by SMEs for the economic development of the Republic of Macedonia with a special emphasis on the measures and actions which have to be taken in the future by the competent authorities for further stimulation of their development.

  18. Role of Relationship Marketing in Small and Medium-Sized Entreprises

    Directory of Open Access Journals (Sweden)

    Ružica Butigan

    2011-06-01

    Full Text Available Along with marketing, small and medium enterprises (SMEs are commonly associated in literature with relationship marketing which results in marketing networks. This paper examines the specific characteristics that differentiate large companies from small and medium-sized enterprises, and the reasons that prevent SMEs from engaging in traditional marketing within the scope of marketing mix. The paper also shows that the key characteristic which distinguishes small from large companies is a prominent role of owner/managers. The owner/manager affects marketing of SMEs by creating his or her own personal networks with stakeholders in the environment, and considers it an important strategic focus and a factor that increases the performance of marketing decision-making. After a thorough review of secondary data sources this paper examines relationship marketing as a marketing framework for SMEs and, finally, proves that relationship marketing is more appropriate for SMEs than are traditional marketing concepts, that relationship marketing and network marketing create an important framework for SMEs and that there is a link between relationship marketing, personal networks and SMEs.

  19. Correlates of Tax Compliance of Small and Medium Size Businesses in Cameroon

    Directory of Open Access Journals (Sweden)

    Oludele Akinloye Akinboade

    2015-12-01

    Full Text Available Taxation provides a predictable and stable flow of revenue to finance development objectives. This is important in a country like Cameroon that has serious challenges with meeting its development objectives. Small and medium enterprises (SMEs are significant for economic growth in the country, contributing as much as about 22 percent of the gross domestic product. SMEs generate taxable incomes. They also collect employment and value added taxes on behalf of the government. Taxation, however, imposes high cost to small businesses. SMEs are less tax compliant in comparison to large businesses. SMEs are considered the ‘hard to tax group from the informal sector.’ As such, the literature suggests that only a fraction of their taxable incomes is reported to tax authorities. Against this background, factors that correlate with tax compliance of 575 small and medium size companies in Cameroon are discussed from a survey of companies in the manufacturing and wholesale sectors. High registration cost and time-consuming processes promote tax non-compliance. The perception that tax system is corrupt discourages registration and filing compliance. When there are too many compliance hurdles, the probability of filing compliance is reduced. However, a fair and static system encourages filing and registration compliance. A clear and consistent tax system promotes filing compliance. Authorities that understand their responsibilities and are willing to respond to enquiries during the registration process promote tax compliance in general.

  20. Variation of IUH shapes with size of rainfall-runoff events in a small agricultural catchment

    Science.gov (United States)

    Banasik, Kazimierz; Hejduk, Leszek; Banasik, Jerzy

    2013-04-01

    Instantaneous unit hydrograph (IUH) is one of the key components in many procedures for design flood estimation. The IUH defined by gamma pdf, called also Nash model, has been estimated for each of the over 30 recorded rainfall-runoff events, in a small (A=82.4 km2), lowland, agricultural catchment located in central Poland, in the period 1980-2010 (Banasik et al., 2011). Variability of the IUH characteristics (such as lag time, time to peak, maximum ordinate) vs. rainfall-runoff parameters (such as peak discharge and runoff depth) will be presented. A larger variability of the IUH characteristics for smaller events was noted. Two methods for estimating, empirically based, representative IUH, for the catchment and for the design flood estimation, are presented. The first one is based on mean values of time to peak and peak ordinate of all individual IUHs, and the other one is taking into account only the largest events when the lag time has tendency to decrease with runoff depth increasing. The empirically estimated representative IUHs are compared with unit hydrograph of FSSR and ReFH (Kjeldsen 2007). Results of single event model application, with the IUH incorporated in it, are compared with results of FFA for this catchment. Banasik K., Hejduk L. and Oygarden L., 2011. Prediction and reduction of diffuse pollution, solid emission and extreme flows from rural areas - case study of small agricultural catchments. Warsaw University of Life Sciences Press, Warsaw. Kjeldsen T.R., 2007. Flood Estimation Handbook, Supplementary Report No. 1. The revitalized FSR/FEH rainfall-runoff method. Centre for Ecology & Hydrology, Wallingford, UK. ACKNOWLEDGMENTS The investigation described in the paper is part of the research project KORANET founded by PL-National Center for Research and Development.

  1. The fate of small-size pericardial heart valve prostheses in an older patient population.

    Science.gov (United States)

    De Paulis, Ruggero; D'Aleo, Salvatore; Bellisario, Alessandro; Salica, Andrea; Weltert, Luca P; Scaffa, Raffaele; Wolf, Lorenzo Guerrieri; Maselli, Daniele; Di Mauro, Michele

    2017-01-01

    Structural valve deterioration (SVD) is the Achilles' heel of bioprostheses. Its correlation with younger age is well known. In recent years we exclusively reserved use of small-size Mitroflow valve prostheses (LivaNova, London, United Kingdom) to an older patient population with small aortic annuli. This study aimed to assess the incidence of SVD and its effect on patient survival and need for reoperation. Two hundred five patients (aged 75.9 ± 5.3 years; range, 62-92 years) underwent aortic valve replacement with a 19-mm or 21-mm Mitroflow valve prosthesis between 2005 and 2011. The great majority was female (n = 170; 83%). In half of patients it was an isolated procedure. All valve prostheses were implanted in a supra-annular position using pledgeted sutures. A 19-mm valve was implanted in 93 patients (45.3%), whereas in 112 patients (54.6%) a 21-mm valve was used. Twenty-three patients (11.2%) were diagnosed with early SVD by echocardiography. Average time from surgery to diagnosis of SVD was 64.3 ± 26.8 months. Ten patients needed a reoperation for SVD. Average time from surgery to a second operation was 45.7 ± 35.7 months. Overall survival was 64.5% and 42.3% at 5 and 9 years, respectively. Cumulative freedom from SVD at 5 and 9 years was 94.8% ± 1.6% and 77.4% ± 5.4%, respectively. In 4 patients death was linked to the presence of SVD. There were no differences in mortality, reoperation, or SVD between the 2 Mitroflow valve sizes. Small-size Mitroflow pericardial valve prostheses have shown a worrisome incidence of SVD even in patients aged >70 years. Based on this experience we have discontinued their use. Copyright © 2016 The American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.

  2. Challenges in Improving Customer Focus in Small-Sized House-building Companies in Brazil

    Directory of Open Access Journals (Sweden)

    Carlos T. Formoso

    2006-12-01

    Full Text Available Some important changes in the business environment in several countries are forcing house-building companies to change their competitive strategies. This paper discusses a set of customer servicing practices, which have been adopted by small-sized house-building companies in Brazil that have been involved in quality management improvement programs, emphasizing customer satisfaction measurement. Such practices are referred to a model of the customer servicing process that integrates the main customer-interaction functions from product inception to building operation. Based on multiple case studies and also on a literature review, the main difficulties faced by this sector in terms of improving customer satisfaction are discussed and some improvement opportunities are pointed out.

  3. Knowledge management in small and medium-sized companies; Wissensmanagement bei kleinen und mittleren Unternehmen

    Energy Technology Data Exchange (ETDEWEB)

    Basu, M. [Netzwirtschaft, EWR Netz GmbH, Worms (Germany); Neises, C. [Regulierungsmanagement, regionetz GmbH, Dueren (Germany)

    2008-12-15

    Knowledge management has now also reached the energy economy, as first branch-specific seminars show. This awakening interest is very much to be welcomed, although until now it has been more the representatives of large energy companies who have made themselves heard. Public utilities, which as a rule are subsumed under the category ''small and medium sized company'', have other possibilities as well as limitations than large corporations when it comes to knowledge management. The present article explains what knowledge management is and how public utilities and regional supply companies can identify and make practical use of opportunities available to them through knowledge management while giving due consideration to their structural characteristics.

  4. Accelerating Innovation in Small and Medium-Sized Enterprises in the ICT Services Sector

    Directory of Open Access Journals (Sweden)

    Juan Vicente García Manjón

    2016-09-01

    Full Text Available This work is aimed at establishing key organizational strategies that push small and medium-sized enterprises (SMEs in the information and communication technologies (ICT services sector to be more innovative. Following an input and output approach, a theoretical model is built that helps determine such key factors. Then the model is validated with fieldwork carried out on a representative sample in Castile-Leon region (Spain. According to this model, the decision to innovate (and the trigger for research and development [R&D] activities in SMEs in the ICT services sector is the result of needs that are presented by customers (public or private sector in tailored projects. All the same, the factors leading to innovation are in order of importance, the technological level of the company, the effort made by the company in R&D, and finally, systems of incentives.

  5. Single-Mirror Small-Size Telescope structure for the Cherenkov Telescope Array

    CERN Document Server

    Niemiec, Jacek; Dyrda, Michał; Kochański, Wojciech; Ludwin, Jaromir; Stodulski, Marek; Ziółkowski, Paweł

    2013-01-01

    A single-mirror small-size (1M-SST) Davies-Cotton telescope has been proposed for the southern observatory of the Cherenkov Telescope Array (CTA) by a consortium of scientific institutions from Poland, Switzerland, and Germany. The telescope has a 4 m diameter reflector and will be equipped with a fully digital camera based on Geiger avalanche photodiodes (APDs). Such a design is particularly interesting for CTA because it represents a very simple, reliable, and cheap solution for a SST. Here we present the design and the characteristics of the mechanical structure of the 1M-SST telescope and its drive system. We also discuss the results of a finite element method analysis in order to demonstrate the conformance of the design with the CTA specifications and scientific objectives. In addition, we report on the current status of the construction of a prototype telescope structure at the Institute of Nuclear Physics PAS in Krakow.

  6. Adoption of an information systems security policy in small and medium sized enterprises.

    Directory of Open Access Journals (Sweden)

    Isabel Maria Lopes

    2017-03-01

    Full Text Available Information Systems Security (ISS is a relevant fact for current organizations. This paper focuses on Small and Medium Sized Enterprises (SMEs. This article aims to constitute an empirical study on the applicability of the Action Research (AR method in information systems, more specifically by assessing the adoption of an ISS policy in six SMEs, and identifying the critical success factors in adopting an ISS policy. The research question we intend to answer is to what extent this research method is adequate to reach the proposed goal. The results of the study suggest that AR is a promising means for the evaluation of ISS policies adoption. It can both act as a research method that improves the understanding about the reasons why the policy has been abandoned, and as a change method, assisting practitioners to overcome barriers and suggesting measures to be implemented.

  7. Supply Chain adoption in Small and Medium-Sized Enterprises (SMEs)

    DEFF Research Database (Denmark)

    Juhl, Mathias Thim; Bernon, Mike

    2016-01-01

    management within SMEs and to further develop frameworks, models and mechanisms that will lead to higher adoption of supply chain capabilities within the SME community. Practical Impact: While this research was exploratory in nature, due to the importance of the SME sector on economic development......Purpose: The importance of having a competitive supply chain strategy is not to be underestimated (Underwood & Agg 2012; Aronow et al. 2014). Despite the importance of creating strong supply chain capabilities, small and medium-sized enterprises (SMEs) find it difficult to implement supply chain...... management (Vaaland & Heide 2007). The aim of this research was to explore supply chain adoption in SMEs. The research was based upon investigating the extent to which supply chain management is adopted by SMEs, and what factors support companies in achieving consistency between supply chain capabilities...

  8. Tax-saving, Innovative Incentives for Small and Medium - Sized Enterprises in Hungary

    Directory of Open Access Journals (Sweden)

    Rita Ambrus

    2012-06-01

    Full Text Available The small-and medium-sized enterprises in the Hungarian economy have been playing a decisive role. Among the difficulties they face during their activities one of the most serious is to raise funds for their labour costs. They try to reduce their tax wedge burden, which is regarded one of the highest in Europe, in various ways. In order to keep the adequate workforce they can provide fringe benefits supplementing to wages and salaries. The cautious application of the referring acts enables companies to motivate workforce and reduce the tax and contribution burdens at the same time. Our research aimed to find an answer how SMEs take these advantages and what factors support or hinder the use of the system.

  9. Energy management assistance for small and medium-size manufacturers, 1989--1990

    Energy Technology Data Exchange (ETDEWEB)

    Law, C.J.; Kirsch, F.W.

    1991-01-01

    Small and medium-size manufacturers continue to express strong confidence in and satisfaction with the energy-conserving and cost-saving services provided by the Energy Analysis and Diagnostic Centers. That conclusion is based upon in-depth interviews with 210 of the 330 manufacturers served by 11 of the EADCs during 1989-90. These interviews were conducted at the manufacturing plants by engineers from the Industrial Technology and Energy Management (ITEM) division of University City Science Center, which manages the EADC program under agreement with the Office of Industrial Technologies, U.S. Department of Energy. University engineering faculty and a mix of graduate and undergraduate students who make up the staff of each EADC perform energy audits under subcontract to the Science Center at manufacturing plants which are located within about 150 miles of the university.

  10. Development of CAPP System for Small and Medium Size Apparel Enterprises

    Institute of Scientific and Technical Information of China (English)

    YIN Ling; ZHANG Wen-bin

    2006-01-01

    Existing computer-aided process planning (CAPP) systems for garment manufacturing emphasize all-purpose ones, lack of specialism and availability. So, few developed is popular in the garment industries. This study is intended for developing a CAPP system, which aims at the actual condition of process planning in the small and medium size apparel enterprises (SMAs). It enables the technologists of process planning to be quicker in generating suitable plans that are similar to existing styles or new. It also automatically provides labor cost by considering the shop-flocr conditions. Process planning is achieved by adopting the Hybrid Interactive-variant process planning method. The proposed system has been realized in Borland Delphi 7 and Oracle 8. For validation of the system,the software has been implemented successfully in a firm named Jingchen in China.

  11. Design of an interdisciplinary engineering elective scoped around collaboration with Small Medium Sized enterprises (SME)

    DEFF Research Database (Denmark)

    Christiansen, Nynne Budtz; Ulrich, Mai-Mai; Pontoppidan, Maja Lund

    2014-01-01

    solving? Do the interdisciplinary teams add value for the SME? The elective SME Innovation and Intrapreneurship has been developed by DTU Diplom a department of the Technical University of Denmark. The department is mainly responsible for the education of the degree Bachelor of Engineering which is a 3......To acquire the right competences as an engineer in the 21st century1 ((King, 2007), you need to be able to work inter-disciplinary and learn the necessary innovation methods and tools2. This paper will strive to answer some of questions identified in the progress of developing and implementing...... of a compulsory 10 ECTS element with focus on interdisciplinary and industry collaboration for all Bachelors of Engineering at The Technical University of Denmark in 2016. As collaboration partner the elective has chosen to work with small and medium sized enterprises (SME) as more than half of the value added...

  12. FINANCING OF FIXED ASSET INVESTMENT IN THE SMALL AND MEDIUM-SIZED ENTERPRISES IN POLAND

    Directory of Open Access Journals (Sweden)

    Beata Geruzel-Dudzińska

    2016-03-01

    Full Text Available Small and medium-sized enterprises play an important role in the economy, creates, because a significant part of GDP, provides employment to many millions of people. One of the main barriers to the development of these enterprises, not only in Poland but also in EU countries, is the scarcity of equity and the difficulty in obtaining external sources of financing. It is not just about lack of funds to finance current operations, but also, and perhaps above all, lack of investment in fixed assets. This paper aims to present available sources of financing of fixed assets for enterprises from the SME sector and the assessment of their use by these companies.

  13. Comparative study of a small size wind generation system efficiency for battery charging

    Directory of Open Access Journals (Sweden)

    Mayouf Messaoud

    2013-01-01

    Full Text Available This paper presents an energetic comparison between two control strategies of a small size wind generation system for battery charging. The output voltage of the direct drive PMSG is connected to the battery through a switch mode rectifier. A DC-DC boost converter is used to regulate the battery bank current in order to achieve maximum power from the wind. A maximum powertracking algorithm calculates the current command that corresponds to maximum power output of the turbine. The DC-DC converter uses this current to calculate the duty cycle witch is necessary to control the pulse width modulated (PWM active switching device (IGPT. The system overview and modeling are presented including characteristics of wind turbine, generator, batteries, power converter, control system, and supervisory system. A simulation of the system is performed using MATLAB/SIMULINK.

  14. Towards „intelligent” financial analysis in the management of small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Bartłomiej Nita

    2015-12-01

    Full Text Available The aim of the paper is to present the possibilities of extending the „intelligence” of financial analysissystems designed for managers of small and medium-sized enterprises (SMEs. The paper first presentsthe question of obtaining analytical information which is essential for supporting managerial decisions,particularly with regard to SMEs. Next, the nature and use of ontologies as well as eye-tracking in modelingmanagerial knowledge in respect of financial analysis are discussed. In the last section the authorsdepict a research experiment that was conducted using eye-tracking, focusing on technical terms, contentand knowledge that can be obtained thanks to this study. In the research experimental methodology wasapplied based on actual financial data, using the Bilander’s BINOCLE and eye-tracking software TobiiStudioTM by Tobii.

  15. Selecting Sustainability Indicators for Small to Medium Sized Urban Water Systems Using Fuzzy-ELECTRE.

    Science.gov (United States)

    Chhipi-Shrestha, Gyan; Hewage, Kasun; Sadiq, Rehan

    2017-03-01

      Urban water systems (UWSs) are challenged by the sustainability perspective. Certain limitations of the sustainability of centralized UWSs and decentralized household level wastewater treatments can be overcome by managing UWSs at an intermediate scale, referred to as small to medium sized UWSs (SMUWSs). SMUWSs are different from large UWSs, mainly in terms of smaller infrastructure, data limitation, smaller service area, and institutional limitations. Moreover, sustainability assessment systems to evaluate the sustainability of an entire UWS are very limited and confined only to large UWSs. This research addressed the gap and has developed a set of 38 applied sustainability performance indicators (SPIs) by using fuzzy-Elimination and Choice Translating Reality (ELECTRE) I outranking method to assess the sustainability of SMUWSs. The developed set of SPIs can be applied to existing and new SMUWSs and also provides a flexibility to include additional SPIs in the future based on the same selection criteria.

  16. Meaningfullness for creation of growth in Small- and Medium-sized enterprises (SMEs)

    DEFF Research Database (Denmark)

    Brink, Tove; Neville, Mette

    2016-01-01

    The research in this paper reveals how meaningfulness of growth can be created in Small- and Medium-sized Enterprises (SMEs). The research is conducted in a four-year period with 24 SMEs participating from different industry branches. The research is now in the late part of the 3rd. year starting...... in 2013 and finished January 2017. Preliminary findings are revealed and have been discussed with the participating SMEs. Important antecedent tensions are present in all SMEs on historical capabilities and the freedom to pursue new ideas as very important for the creation of meaningfulness for utilizing...... create tensions to overcome, which takes time. Additionally the daily operations tend to get more awareness on behalf on the more long-term development of innovation and growth. The meaningfulness created therefore has to be robust to get enough prioritisation to pursue the new ideas for innovation...

  17. HRM implications for network collaboration of small and medium sized companies

    DEFF Research Database (Denmark)

    Kesting, Peter; Müller, Sabine; Jørgensen, Frances

    , we propose that Human Resource Management (HRM) may provide a means by which SMEs can increase their capacity for deriving value from innovation networks, which is a rather unexplored area of the literature. To begin, we present a brief review of the relevant literature on networks, and innovation......Collaboration in innovation networks is particularly important for small and medium enterprises (SMEs) to remain competitive in a rapidly changing environment. Collaboration may however be particularly challenging for SMEs, due to their size and their inherent shortage of resources. In this paper...... in networks in particular, and HRM. We then analyze current models and empirical studies aimed at identifying specific HRM practices that support innovation and evaluate their applicability to SMEs in innovation networks. We argue that the HRM implications for network collaboration of SMEs are considerable...

  18. Documentation of New Promotion Approaches in Small and Medium Sized Businesses of the Textile Industry

    Directory of Open Access Journals (Sweden)

    Mehran Rezvani

    2012-01-01

    Full Text Available The most important marketing activity of the owner/manager of SMEs is to concentrate on entrepreneurial promotion methods of their businesses. New and entrepreneurial promotion plays a leading role in progress and development of SMEs. There has been an emerging concentration on the concept of promotion and the role of its elements in progress of SMEs in marketing research. The purpose of this paper is to identify and document promotion methods in small and medium sized businesses of the textile industry, particularly in Iran. In order to identify the concepts and methods of promotion and to present practical results in this context, a quality research has been conducted by interviewing the owners/managers of SMEs.

  19. Documentation of New Promotion Approaches in Small and Medium Sized Businesses of the Textile Industry

    Directory of Open Access Journals (Sweden)

    Mehran Rezavani

    2012-06-01

    Full Text Available The most important marketing activity of the owner/manager of SMEs is to concentrate on entrepreneurial promotion methods of their businesses. New and entrepreneurial promotion plays a leading role in progress and development of SMEs. There has been an emerging concentration on the concept of promotion and the role of its elements in progress of SMEs in marketing research. The purpose of this paper is to identify and document promotion methods in small and medium sized businesses of the textile industry, particularly in Iran. In order to identify the concepts and methods of promotion and to present practical results in this context, a quality research has been conducted by interviewing the owners/managers of SMEs.

  20. Improved Cost Management at Small and Medium Sized Road Transport Companies: Case Hungary

    Directory of Open Access Journals (Sweden)

    Zoltan Bokor

    2015-10-01

    Full Text Available Small and medium sized road freight transport companies located in Hungary are facing strong competition on the logistics market. An advanced cost management system supporting decisions on capacity allocations or pricing may be a competitive advantage for them and indirectly for the whole economy as well. Still, they generally apply simple, traditional cost calculation regimes, potentially sufficient in case of a homogeneous service portfolio. Nevertheless, road haulage companies with heterogeneous service structures may witness information distortions when using traditional costing methods. So it might be recommended for them to introduce better costing principles. To support an improved transport costing, a multi-level full cost allocation model has been set up and tested in this paper. The research results have pointed out that such a methodological development accompanied by the extension of the data collection mechanism can contribute to making the cost management systems of road freight transport companies more effective.

  1. Estimating survival rates in ecological studies with small unbalanced sample sizes: an alternative Bayesian point estimator

    Directory of Open Access Journals (Sweden)

    Christian Damgaard

    2011-12-01

    Full Text Available Increasingly, the survival rates in experimental ecology are presented using odds ratios or log response ratios, but the use of ratio metrics has a problem when all the individuals have either died or survived in only one replicate. In the empirical ecological literature, the problem often has been ignored or circumvented by different, more or less ad hoc approaches. Here, it is argued that the best summary statistic for communicating ecological results of frequency data in studies with small unbalanced samples may be the mean of the posterior distribution of the survival rate. The developed approach may be particularly useful when effect size indexes, such as odds ratios, are needed to compare frequency data between treatments, sites or studies.

  2. Bank Finance For Small And Medium-Sized Enterprises In Sri Lanka: Issues And Policy Reforms

    Directory of Open Access Journals (Sweden)

    Gamage Pandula

    2015-08-01

    Full Text Available Access to bank finance is necessary to create an economic environment that enables Small and Medium-sized enterprises (SMEs to grow and prosper. The SMEs in Sri Lanka, however, face significant constraints to access bank finance. The purpose of this paper is to investigate the access to bank finance and related issues in the SME sector of Sri Lanka. The paper is exploratory in nature and reviews the bank financing situation for SMEs in Sri Lanka, as well as provides an overview of constraints faced by the banks (supply-side and SMEs (demand-side. The paper also highlights some good practices in SME lending from international experience and outlines some recommendations to help overcome the constraints faced by the banks and SMEs. The recommendations discussed in this paper may be of importance to policymakers, not only in Sri Lanka, but in many other developing countries in a similar stage of economic growth.

  3. Synthesis and characterization of extremely small gold nanoshells, and comparison of their photothermal conversion capacity with gold nanorods

    Science.gov (United States)

    Durán-Meza, A. L.; Moreno-Gutiérrez, D. S.; Ruiz-Robles, J. F.; Bañuelos-Frías, A.; Segovia-González, X. F.; Longoria-Hernández, A. M.; Gomez, E.; Ruiz-García, J.

    2016-05-01

    The current methods for preparing gold nanoshells (AuNSs) produce shells with a diameter of approximately 40 nm or larger, with a relatively large polydispersity. However, AuNSs with smaller diameters and more monodispersity are better suited for biomedical applications. In this work, we present a modified method for the preparation of AuNSs, based on the use of sacrificial silver nanoparticles (AgNPs). We customized the Lee-Meisel method to prepare small and monodisperse AgNPs that were used as sacrificial nanoparticles to prepare extremely small monodispersed AuNSs with an average diameter from 17 to 25 +/- 4 nm. We found that these AuNSs are faceted, and that the oxidized silver likely dissolves out of the nanoparticles through some of the facets on the AuNSs. This leads to a silver oxide plug on the surface of the AuNSs, which has not been reported before. The smaller AuNSs, prepared under the best conditions, absorb in the near infrared region (NIR) that is appropriate for applications, such as photothermal therapy or medical imaging. The AuNSs showed absorption peaks in the NIR similar to those of gold nanorods (AuNRs) but with better photothermal capacity. In addition, because of their negative charge, these AuNSs are more biocompatible than the positively charged AuNRs. The synthesis of small, monodisperse, stable and biocompatible nanoparticles, like the ones presented in this work, is of prime importance in biomedical applications.The current methods for preparing gold nanoshells (AuNSs) produce shells with a diameter of approximately 40 nm or larger, with a relatively large polydispersity. However, AuNSs with smaller diameters and more monodispersity are better suited for biomedical applications. In this work, we present a modified method for the preparation of AuNSs, based on the use of sacrificial silver nanoparticles (AgNPs). We customized the Lee-Meisel method to prepare small and monodisperse AgNPs that were used as sacrificial nanoparticles to

  4. Survey of food safety practices on small to medium-sized farms and in farmers markets.

    Science.gov (United States)

    Harrison, Judy A; Gaskin, Julia W; Harrison, Mark A; Cannon, Jennifer L; Boyer, Renee R; Zehnder, Geoffrey W

    2013-11-01

    As produce consumption has increased, so have foodborne disease outbreaks associated with fresh produce. Little research has addressed food safety practices used on small to medium-sized farms selling locally or in farmers markets. This study evaluated current food safety practices used by farmers on small to medium-sized farms and managers of farmers markets in Georgia, Virginia, and South Carolina based on responses to surveys. Surveys were developed, pretested, and revised before implementation with target audiences and were implemented via mail and the Web to maximize participation, with reminders sent to nonrespondents. Data were collected from 226 farmers and 45 market managers. Frequencies and percentages were calculated for all response variables. Responses from farmers indicated that more than 56% of them use manures. Of those who use manures, 34% use raw or mixtures of raw and composted manure, and over 26% wait fewer than 90 days between application of raw manure and harvest. Over 27% use water sources that have not been tested for safety for irrigation, and 16% use such water sources for washing produce. Over 43% do not sanitize surfaces that touch produce at the farm. Only 33% of farmers always clean transport containers between uses. Responses from market managers indicated that over 42% have no food safety standards in place for the market. Only 2 to 11% ask farmers specific questions about conditions on the farm that could affect product safety. Less than 25% of managers sanitize market surfaces. Only 11% always clean market containers between uses. Over 75% of markets offer no sanitation training to workers or vendors. While farmers and market managers are using many good practices, the results indicate that some practices being used may put consumers at risk of foodborne illness. Consequently, there is a need for training for both farmers and market managers.

  5. EXTERNAL FORCES DRIVING CHANGE IN THE ROMANIAN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Roiban Roxana Nadina

    2012-07-01

    Full Text Available Change is a constant in everyday life confronting organizations to continuously adapt their strategy, structure, processes, and culture in order to survive and stay competitive on the market. Implementing organizational change is one of the most important skills required for managers and in the meantime the most difficult one. The forces driving change within an organization, that can be either external or internal, are those that propel a company forward towards change and in order to identify the need for change and make the proper changes, managers have to develop a tool that allows them to analyze how does the environment influence their business activities. A vision for change will clarify the directions in which the organization needs to move, starting from its current state and taking in consideration the existing opportunities and threats from the environment that allow to move to a future desired state. The purpose of this paper is to identify the concern for change in the Romanian small and medium sized enterprises by presenting and explaining the past and present influences of the main external forces that have determined the need for change in the last 3-5 years and to make recommendations about future possible changes that have to be performed by managers for a better harmonization with the environment. The research method used for this study is the interview on a sample that contains some of the most relevant SME’s from the western side of Romania, from different industries. We analyzed the main external forces that had an impact on the small and medium sized enterprises and how were they generating the need for organizational change, in order to see which present and future changes are required.

  6. Traditional Small-Size Citrus from Taiwan: Essential Oils, Bioactive Compounds and Antioxidant Capacity

    Directory of Open Access Journals (Sweden)

    Min-Hung Chen

    2017-05-01

    Full Text Available Background: The calamondin (Citrus microcarpa Bunge and the kumquat (Fortunella crassifolia Swingle are two small-size citrus fruits that have traditionally been consumed in Taiwan; however, there has been a lack of scientific research regarding the active compounds and functionalities of these fruits. Methods: Analysis of volatile composition of essential oil and phytosterol was carried out using Gas Chromatography–Mass Spectrometry (GC-MS. Flavonoid and limonoid were analyzed by High Performance Liquid Chromatography (HPLC. Moreover, antioxidant capacity from their essential oils and extracts were assessed in vitro. Results: The compositions of the essential oils of both fruits were identified, with the results showing that the calamondin and kumquat contain identified 43 and 44 volatile compounds, respectively. In addition, oxygenated compounds of volatiles accounted for 4.25% and 2.04%, respectively, consistent with the fact that oxygenated compounds are generally found in high content in citrus fruits. In terms of flavonoids, the calamondin exhibited higher content than the kumquat, with disomin-based flavonoids being predominant; on the other hand, phytosterol content of kumquat was higher than that of calamondin, with amyrin being the dominant phytosterol. Both of them contain high amounts of limonoids. The ethanol extracts and essential oils of small-sized citrus fruits have been shown to have antioxidant effects, with those effects being closely related to the flavonoid content of the fruit in question. Conclusions: The present study also reviewed antioxidant activity in terms of specific bioactive compounds in order to find the underlying biological activity of both fruits. The calamondin and kumquat have antioxidant effects, which are in turn very important for the prevention of chronic diseases.

  7. Fish population size and movement patterns in a small intermittently open South African estuary

    Science.gov (United States)

    Lukey, J. R.; Booth, A. J.; Froneman, P. W.

    2006-03-01

    The population size and movement patterns of small fish (>50 mm SL) in a small intermittently open estuary (Grant's Valley estuary: 33°40'12.1″S, 26°42'12.6″E) situated on the south-east Cape coast of South Africa were examined during the closed phase over the period May and August 2004. The estuary was subdivided into four discrete areas and the fish within each area sampled using a 30 m seine net (15 mm mesh). Fish captured were marked by fin clipping according to the area of capture. Fish population size was estimated by using three methods: the Schnabel estimator, the Hilborn estimator, and a derived estimator. A total of 12 species was captured and marked during the study. The total number of fish in the estuary was estimated at ca. 12 000 individuals (11 219-13 311). Marine-breeding species ( Rhabdosargus holubi, Monodactylus falciformis, and two mullet species) numerically dominated the ichthyofauna, possibly as a result of their effective use of overtopping events, when seawater washes over the sandbar, to enter the estuary during the closed mouth phase. The two mullet species, Myxus capensis and Liza richardsonii, and the Cape stumpnose, R. holubi moved extensively throughout the estuary, while the remaining species exhibited restricted movement patterns possibly due to the preference for refuge and foraging areas associated with reed beds. The observed movement patterns of individual fish species appeared to be associated with both foraging behaviour and habitat selection.

  8. Mechanical weed control on small-size dry bean and its response to cross-flaming

    Energy Technology Data Exchange (ETDEWEB)

    Martelloni, L.; Frasconi, C.; Fontanelli, M.; Raffaelli, M.; Peruzzi, A.

    2016-11-01

    Dry bean (Phaseolus vulgaris L.) can be a profitable crop for farmers; however controlling weeds effectively without a decrease in yield remains a problem. An example where mechanical weed control is difficult to conduct is dry bean ‘Toscanello’, which is a small sized high-income niche product growing low to the ground. Concerning intra-row weed control, also flame weeding could be an opportunity but the dry bean heat tolerance needs to be studied. The aims of this research were to study the weed control efficacy of a spring-tine harrow and an inter-row cultivator in this bean variety, and to test the tolerance of dry bean cultivated under weed-free conditions to cross-flaming applied with different liquefied petroleum gas (LPG) doses. Flame weeding was applied at BBCH 13 and BBCH 14 bean growth stages by pairs of burners producing direct double flame acting into the intra-row space, with bean plants placed in the middle. The results suggest that the spring-tine harrow used two times at BBCH 13 and 14, respectively, lead to a yield similar to that of the weedy control. The inter-row cultivator could be an opportunity for small-sized dry bean crops producers, enabling them to obtain a similar yield compared to the hand-weeded control. Concerning the bean tolerance to cross-flaming the results showed that bean flamed at BBCH 13 stage had little tolerance to cross-flaming. Bean flamed at BBCH 14 stage was tolerant until an LPG dose of 39 kg/ha, giving yield responses similar to those observed in the non-flamed control. (Author)

  9. Adoption of the International Accounting Standard by Small and Medium-Sized Entities and its Effects on Credit Granting

    National Research Council Canada - National Science Library

    Enrico Dalla Riva; Bruno Meirelles Salotti

    2015-01-01

    This research examines the relationship between the adoption of the international accounting standard by small and medium-sized entities in Brazil and the cost of credit granted by financial institutions...

  10. Innovation Gateways for SMEs: Finding the Formula for Successful Interaction between Universities and Small and Medium-Size Firms.

    Science.gov (United States)

    Davies, Peter T.

    1995-01-01

    The University of Warwick's Breakthrough Technologies program links with small and medium-sized businesses to stimulate awareness of innovations. The Manufacturing Excellence Initiative provides postgraduate training for company staff that focuses on best practices and change management. (SK)

  11. Exploring the SME Quandary: Data Governance in Practise in the Small to Medium-Sized Enterprise Sector

    National Research Council Canada - National Science Library

    Carolyn Begg; Tom Caira

    2012-01-01

    The purpose of this paper is to explore how small to medium-sized enterprises (SMEs) perceive data and data governance and investigates whether current data governance frameworks are applicable to SMEs...

  12. Using multi-theory model to predict initiation and sustenance of small portion size consumption among college students

    Directory of Open Access Journals (Sweden)

    Manoj Sharma

    2016-08-01

    Conclusion: Based on this study’s findings, MTM appears to be a robust theoretical framework for predicting small portion size consumption behavior change. Interventions in this regard need to be designed.

  13. Credit Rationing and the Simulation of Bank-Small and Medium Sized Firm Artificial Credit Market

    Institute of Scientific and Technical Information of China (English)

    LIU Xuefeng; ZHANG Wei; XIONG Xiong; SHEN Dehua; ZHANG Yongjie

    2016-01-01

    By analyzing the financing difficulties faced by the small and medium-sized firms,the paper built an artificial credit markets with the agent-based computational modeling to simulate the real world credit transactions.There are firms,banks,different risk-type projects as well as legal and supervision environments in which debt contracts constitute the financial instruments.The simulation results show that the number of collateral,average success probability of projects,and the prime interest rate have materially impact on bank's average profit,bank's capital,the overall interest rate,the number of borrowing firms,loan size,and the degree of credit rationing.These results in line with those of the classical S-W model in the sense that the relationship between bank profits and interest rates is non-monotonic as well as the relationship between credit rationing and interest rates.And thus there is an adverse selection effect in credit rationing theory.

  14. Williamson-Hall analysis and optical properties of small sized ZnO nanocrystals

    Science.gov (United States)

    Kalita, Amarjyoti; Kalita, Manos P. C.

    2017-08-01

    We apply Williamson-Hall (WH) method of X-ray diffraction (XRD) line profile analysis for lattice strain estimation of small sized ZnO nanocrystals (crystallite size≈4 nm). The ZnO nanocrystals are synthesized by room temperature chemical co-precipitation followed by heating at 40 °C. Zinc acetate, sodium hydroxide and 2-mercaptoethanol (ME) are used for the synthesis of the nanocrystals. {100}, {002}, {101} and {200}, {112}, {201} line profiles in the XRD pattern are significantly merged, therefore determination of the full width at half maximum values and peak positions of the line profiles required for WH analysis has been carried out by executing Rietveld refinement of the XRD pattern. Lattice strain of the 4 nm sized ZnO nanocrystals is found to be 5.8×10-3 which is significantly higher as compared to the literature reported values for larger ones (crystallite size≈17-47 nm). Role of ME as capping agent is confirmed by Fourier transform infrared spectroscopy. The band gap of the nanocrystals is determined from the UV-Visible absorption spectrum and is found to be 3.68 eV. The photoluminescence spectrum exhibits emissions in the visible (408 nm-violet, 467 nm-blue and 538 nm-green) regions showing presence of zinc interstitial and oxygen vacancy in the ZnO nanocrystals.

  15. The dual-mirror Small Size Telescope for the Cherenkov Telescope Array

    CERN Document Server

    Pareschi, G; Antonelli, L A; Bastieri, D; Bellassai, G; Belluso, M; Bigongiari, C; Billotta, S; Biondo, B; Bonanno, G; Bonnoli, G; Bruno, P; Bulgarelli, A; Canestrari, R; Capalbi, M; Caraveo, P; Carosi, A; Cascone, E; Catalano, O; Cereda, M; Conconi, P; Conforti, V; Cusumano, G; De Caprio, V; De Luca, A; Di Paola, A; Di Pierro, F; Fantinel, D; Fiorini, M; Fugazza, D; Gardiol, D; Ghigo, M; Gianotti, F; Giarrusso, S; Giro, E; Grillo, A; Impiombato, D; Incorvaia, S; La Barbera, A; La Palombara, N; La Parola, V; La Rosa, G; Lessio, L; Leto, G; Lombardi, S; Lucarelli, F; Maccarone, M C; Malaguti, G; Malaspina, G; Mangano, V; Marano, D; Martinetti, E; Millul, R; Mineo, T; MistÒ, A; Morello, C; Morlino, G; Panzera, M R; Rodeghiero, G; Romano, P; Russo, F; Sacco, B; Sartore, N; Schwarz, J; Segreto, A; Sironi, G; Sottile, G; Stamerra, A; Strazzeri, E; Stringhetti, L; Tagliaferri, G; Testa, V; Timpanaro, M C; Toso, G; Tosti, G; Trifoglio, M; Vallania, P; Vercellone, S; Zitelli, V; Amans, J P; Boisson, C; Costille, C; Dournaux, J L; Dumas, D; Fasola, G; Hervet, O; Huet, J M; Laporte, P; Rulten, C; Sol, H; Zech, A; White, R; Hinton, J; Ross, D; Sykes, J; Ohm, S; Schmoll, J; Chadwick, P; Greenshaw, T; Daniel, M; Cotter, G; Varner, G S; Funk, S; Vandenbroucke, J; Sapozhnikov, L; Buckley, J; Moore, P; Williams, D; Markoff, S; Vink, J; Berge, D; Hidaka, N; Okumura, A; Tajima, H

    2013-01-01

    In this paper, the development of the dual mirror Small Size Telescopes (SST) for the Cherenkov Telescope Array (CTA) is reviewed. Up to 70 SST, with a primary mirror diameter of 4 m, will be produced and installed at the CTA southern site. These will allow investigation of the gamma-ray sky at the highest energies accessible to CTA, in the range from about 1 TeV to 300 TeV. The telescope presented in this contribution is characterized by two major innovations: the use of a dual mirror Schwarzschild-Couder configuration and of an innovative camera using as sensors either multi-anode photomultipliers (MAPM) or silicon photomultipliers (SiPM). The reduced plate-scale of the telescope, achieved with the dual-mirror optics, allows the camera to be compact (40 cm in diameter), and low-cost. The camera, which has about 2000 pixels of size 6x6 mm^2, covers a field of view of 10{\\deg}. The dual mirror telescopes and their cameras are being developed by three consortia, ASTRI (Astrofisica con Specchi a Tecnologia Repl...

  16. Evaluating shock absorption behavior of small-sized systems under programmable electric field.

    Science.gov (United States)

    Jagtap, Piyush; Kumar, Praveen

    2014-11-01

    A simple ball-drop impact tester is developed for studying the dynamic response of hierarchical, complex, small-sized systems and materials. The developed algorithm and set-up have provisions for applying programmable potential difference along the height of a test specimen during an impact loading; this enables us to conduct experiments on various materials and smart structures whose mechanical behavior is sensitive to electric field. The software-hardware system allows not only acquisition of dynamic force-time data at very fast sampling rate (up to 2 × 10(6) samples/s), but also application of a pre-set potential difference (up to ±10 V) across a test specimen for a duration determined by feedback from the force-time data. We illustrate the functioning of the set-up by studying the effect of electric field on the energy absorption capability of carbon nanotube foams of 5 × 5 × 1.2 mm(3) size under impact conditions.

  17. Autoregressive Prediction with Rolling Mechanism for Time Series Forecasting with Small Sample Size

    Directory of Open Access Journals (Sweden)

    Zhihua Wang

    2014-01-01

    Full Text Available Reasonable prediction makes significant practical sense to stochastic and unstable time series analysis with small or limited sample size. Motivated by the rolling idea in grey theory and the practical relevance of very short-term forecasting or 1-step-ahead prediction, a novel autoregressive (AR prediction approach with rolling mechanism is proposed. In the modeling procedure, a new developed AR equation, which can be used to model nonstationary time series, is constructed in each prediction step. Meanwhile, the data window, for the next step ahead forecasting, rolls on by adding the most recent derived prediction result while deleting the first value of the former used sample data set. This rolling mechanism is an efficient technique for its advantages of improved forecasting accuracy, applicability in the case of limited and unstable data situations, and requirement of little computational effort. The general performance, influence of sample size, nonlinearity dynamic mechanism, and significance of the observed trends, as well as innovation variance, are illustrated and verified with Monte Carlo simulations. The proposed methodology is then applied to several practical data sets, including multiple building settlement sequences and two economic series.

  18. Encapsulated multicellular tumor spheroids as a novel in vitro model to study small size tumors

    Directory of Open Access Journals (Sweden)

    Markvicheva Elena

    2003-01-01

    Full Text Available Presently multicellular tumor spheroids (MTS are being widely used in various aspects of tumor biology, including studies in biology and photodynamic therapy. The cellular organization of spheroids allows the recreation of in vivo small tumors much better than all common two-dimensional in vitro models. The cell encapsulation method could be proposed as a novel technique to quickly and easily prepare a large number of spheroids with narrow size distribution within a desirable diameter range. Moreover, the proposed technique for spheroid generation using encapsulated growing tumor cells could provide entirely new avenues to develop a novel spheroid co-culture model (for instance, the in vitro co-cultvation of tumor cells and monocytes, or epithelial cells, or fibroblasts etc. The current research was aimed at developing a simple and reliable method to encapsulate tumor cells and to cultivate them in vitro. In order to generate spheroids, MCF-7 cells were encapsulated and cultivated in 200 ml T-flasks in a 5% CO2 atmosphere at 37°C for 4-5 weeks. The cell proliferation was easily observed using a light microscope. The cells grew in aggregates increasing in size with time. The cell growth resulted in the formation of large cell clusters (spheroids which filled the whole microcapsule volume in 4-5 weeks.

  19. Hybrid neural intelligent system to predict business failure in small-to-medium-size enterprises.

    Science.gov (United States)

    Borrajo, M Lourdes; Baruque, Bruno; Corchado, Emilio; Bajo, Javier; Corchado, Juan M

    2011-08-01

    During the last years there has been a growing need of developing innovative tools that can help small to medium sized enterprises to predict business failure as well as financial crisis. In this study we present a novel hybrid intelligent system aimed at monitoring the modus operandi of the companies and predicting possible failures. This system is implemented by means of a neural-based multi-agent system that models the different actors of the companies as agents. The core of the multi-agent system is a type of agent that incorporates a case-based reasoning system and automates the business control process and failure prediction. The stages of the case-based reasoning system are implemented by means of web services: the retrieval stage uses an innovative weighted voting summarization of self-organizing maps ensembles-based method and the reuse stage is implemented by means of a radial basis function neural network. An initial prototype was developed and the results obtained related to small and medium enterprises in a real scenario are presented.

  20. Knowledge, attitude, and practice of quality standards in small-sized public hospitals, Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Fahad Khamis Alomari

    2015-01-01

    Full Text Available Objectives: The aim of this study was to assess current situations in small size hospitals regarding knowledge of staff, their attitude and practice of quality standards, in order to set a plan to improve the current situations and overcome barriers of quality practice. Materials and Methods: A descriptive cross-sectional research was conducted by a validated self-administered questionnaire using systematic random technique. Results: The study included about 37.7% Physicians followed by 28.3% nurses, and 18.8% administrators. Median percentage of participants′ knowledge and attitude scores regarding healthcare quality was 48% and 80% respectively. Meanwhile, the median percentage of participants′ perception toward hospital support and implementation of healthcare quality was 54% and 50% respectively. The main barriers for quality standards implementation and practicing were; staff resistance (84.8% followed by deficient knowledge (81.1%. Knowledge showed significant positive correlation with hospital application of quality standards (P = 0.001. Conclusion: The researcher concluded that improvement of knowledge and attitude toward implementation of quality standards as well as leadership commitment to quality and change management were a critical element for organisational shifting transformation to implementing quality of care. Focusing on small hospital and providing more support with all resources for implementation of quality standards through proper education and training for all staff categories are highly recommended.

  1. Business Benefits from Enterprise Systems Implementation in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Sanjay Mathrani

    2009-08-01

    Full Text Available The market for enterprise systems (ESs continues to grow as business becomes increasingly global and competitive. Increasingly, the market focus for ES vendors is on small businesses. The purpose of this study is to provide a unique ES vendor/consultant perspective on (a the business benefits small and medium-sized enterprises (SMEs expect from their ES investment and (b to examine current practices of ES implementation in SMEs through a conceptual framework that considers the organisational, process and strategic context of the implementation. This study does so with interview data collected from ES vendors, ES consultants and IT research firms, who are the key players in the New Zealand ES industry. A distinctive contribution of this research is the vendor/consultant perspective as the unit of analysis, rather than the SME perspective commonly used in similar research. The vendor/consultant perspective offers a comprehensive viewpoint that extends across numerous SMEs in a variety of industries. Findings from interviews with these professionals indicate that although many ES implementations are several years old now, SMEs have only recently started tracking benefits through analytical processes in expectation to realise business value from their ES investment. The results also identify how ES implementation practices are adapting to be more suitable to the SME sector, an important market for ES vendors given the saturation of the large enterprise market for ES implementation.

  2. Resource efficiency and culture--workplace training for small and medium-sized enterprises.

    Science.gov (United States)

    Bliesner, Anna; Liedtke, Christa; Rohn, Holger

    2014-05-15

    Although there are already some qualification offers available for enterprises to support resource efficiency innovations, the high potentials that can be identified especially for small and medium sized enterprises (SMEs) have not been activated until now. As successful change lies in the hands of humans, the main aim of vocational education has to be the promotion of organisational and cultural changes in the enterprises. As there is already a small but increasing number of enterprises that perform very well in resource efficiency innovations one question arises: What are typical characteristics of those enterprises? Leaning on a good-practice approach, the project "ResourceCulture" is going to prove or falsify the hypothesis that enterprises being successful with resource efficiency innovations have a specific culture of trust, which substantially contributes to innovation processes, or even initially enables them. Detailed empirical field research will light up which correlations between resource efficiency, innovation and cultures of trust can be found and will offer important aspects for the improvement of management instruments and qualification concepts for workplace training. The project seizes qualification needs that were likewise mentioned by enterprises and consultants, regarding the implementation of resource efficiency. This article - based on first empirical field research results - derives preliminary indications for the design of the qualification module for the target groups resource efficiency consultants and managers. On this basis and in order to implement "ResourceCulture" conceptual and methodological starting points for workplace training are outlined. Copyright © 2013 Elsevier B.V. All rights reserved.

  3. PROSPECTS OF DEVELOPMENT OF SMALL AND MEDIUM-SIZED ENTERPRISES IN UKRAINIAN AGRICULTURE

    Directory of Open Access Journals (Sweden)

    O. Pimenova

    2016-06-01

    Full Text Available Main directions of development of small and medium-sized enterprises in Ukrainian agriculture are examined. It is determined that entrepreneurship in agrarian sector is a driving force behind the development of agriculture, as these activities contributes to the production of quality agricultural products that satisfies the needs of society, food security, independence and improves the living standards of rural population. Potential customers of small parties of harvest in Ukrainian grain market are analyzed. The ways of mutually beneficial cooperation between Ukrainian farmers and entrepreneurs are proved. The study of foreign experience has proven that strengthening the competitiveness of Ukrainian agricultural products in the context of globalization is possible on the basis of mutually beneficial cooperation of Ukrainian farmers and entrepreneurs, where recent purchase of output at market prices for the purpose of resale or creation of agricultural cooperatives, such form of economy in agrarian relations that combines a balanced economic, social and environmental components. In particular in paper is shown that sustainable economic management provide only forms of economy that take into account the socioeconomic and geophysical specifics of agriculture, particularities of agricultural labor and methods of management. The most common among these forms are farmers.

  4. ADVANTAGES OF CROWDFUNDING AS AN ALTERNATIVE SOURCE OF FINANCING OF SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Zorica Golić

    2014-08-01

    Full Text Available The lack of funding, and limited access to it are the basic problems faced by small and medium-sized enterprises (SMEs. Given the great role and importance of SMEs in every national economy, any progress in solving these problems in terms of creating and finding alternative sources of funding should attract great attention in both professional and scientific and the wider socio-political communities. Crowdfunding is an innovative and relatively new concept that connects entrepreneurs and investors through the Internet. This method allows the entrepreneurs to collect funds through the Internet by "open invitation" to finance their projects/ventures and thus raise the necessary funds by relatively small contributions of a relatively large number of investors. As such, crowdfunding is a fast-growing model increasingly debated of in academic circles and the European institutions. This paper will consider crowdfunding as an alternative means of financing SMEs and try to give different aspects of crowdfunding - and explain how it works, what are the advantages of using it for SMEs and thus expand the knowledge on the topic.

  5. Controlled emission and coupling of small-size YAG:Ce3+ nanocrystals to gold nanowire

    CERN Document Server

    Birowosuto, M D; Donega, C de Mello; Meijerink, A

    2015-01-01

    We report a controlled emission of Ce3+ ions inside single Yttrium Aluminum Gar- net Y3Al5O12 (YAG:Ce3+) nanocrystals with a diameter of 22 +- 10 nm as a result of a coupling of a surface plasmon mode propagating along single gold nanowire (NW). From the PL images, the intensity for single YAG:Ce3+ nanocrystals in the proximity of the single gold NW increases by a factor of two in comparison with that without the NW. Also, we observe a maximum of 3.8-fold emission rate en- hancements for the single nanocrystal close to the single gold NW. The emission rate enhancements of YAG:Ce3+ nanocrystals are two folds the enhancements of 100-nm fluorescent nanospheres. This value is in agreement with the calculation of a combi- nation from the analytical scattering model and boundary element method (BEM). We also confirm that the small size light sources are more efficient for the emission rate enhancements. Thus, the controlled emission of small YAG:Ce3+ nanocrystals with the perfect photostabilities will pave the way ...

  6. Specificities of the small and medium-sized enterprises in the Czech Republic and EU

    Directory of Open Access Journals (Sweden)

    Helena Chládková

    2010-01-01

    Full Text Available Small and medium enterprises (SME are the engine of the European economy. They are an essential source of jobs, create entrepreneurial spirit and innovation in the EU and are thus crucial for fostering competitiveness and employment. In the enlarged European Union of 27 countries, some 20 million SMEs provide around 75 million jobs and represent 99 % of all enterprises. However, they are often confronted with market imperfections. SMEs frequently have difficulties in obtaining capital or credit, particularly in the early start–up phase. Their limited resources may also restrict access to new technology or innovation. It is therefore necessary to monitor the development of SMEs in individual EU countries and highlighting their problems and mainly to their importance.During the recent period of time there have been many researchers from the FBE Mendel University in Brno, who focused on the analysis of the small and medium-sized enterprise, e.g. Bohušová (2007; Chládková (2009; Nerudová a Bohušová (2008; Kubíčková a Peprný (2006; Zrůst a Pyšný (2008. This paper is the part of the Research proposal MSM 6215648904 being solved at the FBE Mendel University in Brno.

  7. Creativity, creations and innovations in the management of small and medium-sized business

    Directory of Open Access Journals (Sweden)

    Usheva M.

    2015-05-01

    Full Text Available Creativity is a process of development and expression of new ideas interwoven in the company mission and vision to lead not only to financial success but also to real loyalty and involvement of the employees with the company problems and achievements. The main objective of this paper is through the research among contemporary managers and entrepreneurs, representatives of small and medium-sized business in the region of Blagoevgrad to prove that creativity skills are deployed in each person, to identify the specific characteristics of the creative thinking of the manager and the tools that stimulate them to increase competitiveness in the context of the sustainable development of the small and medium business in international and domestic tourism market. The main result to be achieved is evidence that when there is adequate (positive self-evaluation, intrinsic motivation or chiefly necessity of creativity manifestation, emotivity in the sense of creative enthusiasm, personal professional effectiveness and appropriate situational factors, the modern manager is able to model conditions for the manifestation of creativity (creative self-expression, both in themselves and in their subordinates. This in turn leads to increased competitiveness and intensive implementation of innovations in the company management and operation. The main research methods used in the study are literature review on the subject, survey, analysis of processes, intuitive and systematic approach, systematic observation, data classification and interpretation.

  8. Thermal utilization opportunities with a small-to-medium sized BWR

    Energy Technology Data Exchange (ETDEWEB)

    Konkin, D.; Simonson, C.J.; Dalai, A.K.; Tanino, K.; Guo, H., E-mail: doug.konkin@usask.ca [Univ. of Saskatchewan, Saskatchewan (Canada); Nishida, K.; Mochida, T. [Hitachi-GE Nuclear Energy, Ltd., Ibaraki (Japan); Ikegawa, T.; Kito, K. [Hitachi, Ltd., Ibaraki (Japan); Knudsen, R. [LeanOptions Consulting, Inc., Regina, Saskatchewan (Canada); Aikman, A. [SNC-Lavalin, Saskatoon, Saskatchewan (Canada); Humphries, R. [AMEC, Toronto, Ontario (Canada)

    2014-07-01

    Hitachi-GE Nuclear Energy Ltd. (Hitachi-GE) has developed a conceptual design for a Double MS: Modular Simplified & Medium Small Reactor (DMS) under the sponsorship of The Japan Atomic Power Company. Recent efforts have yielded enhancements for improved safety and reactor core performance. The DMS is an innovative small-to-medium sized Boiling Water Reactor (BWR), which, based only on electricity generation, has been estimated to almost overcome economy of scale concerns when compared to proven conventional Advanced Boiling Water Reactor (ABWR) technologies. In order to make the DMS more attractive, the University of Saskatchewan (U of S), Hitachi-GE and Hitachi Ltd. (Hitachi) have collaborated on a joint research and development (R&D) initiative to study the utilization of heat and steam from the Balance of Plant (BOP) associated with the DMS for thermal utilization (TU) applications. In this paper, the advanced features of the DMS and the individual projects of the R&D program will be described. (author)

  9. Change in genetic size of small-closed populations: lessons from a domestic mammal population

    Directory of Open Access Journals (Sweden)

    Farhad Ghafouri-Kesbi

    2010-01-01

    Full Text Available The aim of this study was to monitor changes in genetic size of a small-closed population of Iranian Zandi sheep, by using pedigree information from animals born between 1991 and 2005. The genetic size was assessed by using measures based on the probability of identity-by-descend of genes (coancestry, f, and effective population size, Ne, as well as measures based on probability of gene origin (effective number of founders, f e, effective number of founder genomes, f g, and effective number of non-founder genomes, f ne. Average coancestry, or the degree of genetic similarity of individuals, increased from 0.81% to 1.44% during the period 1993 to 2005, at the same time that Ne decreased from 263 to 93. The observed trend for f e was irregular throughout the experiment in a way that f e was 68, 87, 77, 92, and 80 in 1993, 1996, 1999, 2002, and 2005, respectively. Simultaneously, f g, the most informative effective number, decreased from 61 to 35. The index of genetic diversity (GD which was obtained from estimates of f g,decreased about 2% throughout the period studied. In addition, a noticeable reduction was observed in the estimates of f ne from 595 in 1993 to 61 in 2005. The higher than 1 ratio of f e to f g indicated the presence of bottlenecks and genetic drift in the development of this population of Zandi sheep. From 1993 to 1999, f ne was much higher than f e, thereby indicating that with respect to loss of genetic diversity, the unequal contribution of founders was more important than the random genetic drift in non-founder generations. Subsequently, random genetic drift in non-founder generations was the major reason for f e> f ne. The minimization of average coancestry in new reproductive individuals was recommended as a means of preserving the population against a further loss in genetic diversity.

  10. Hybrid Guidance Control for a Hypervelocity Small Size Asteroid Interceptor Vehicle

    Science.gov (United States)

    Zebenay, Melak M.; Lyzhoft, Joshua R.; Barbee, Brent W.

    2017-01-01

    Near-Earth Objects (NEOs) are comets and/or asteroids that have orbits in proximity with Earth's own orbit. NEOs have collided with the Earth in the past, which can be seen at such places as Chicxulub crater, Barringer crater, and Manson crater, and will continue in the future with potentially significant and devastating results. Fortunately such NEO collisions with Earth are infrequent, but can happen at any time. Therefore it is necessary to develop and validate techniques as well as technologies necessary to prevent them. One approach to mitigate future NEO impacts is the concept of high-speed interceptor. This concept is to alter the NEO's trajectory via momentum exchange by using kinetic impactors as well as nuclear penetration devices. The interceptor has to hit a target NEO at relative velocity which imparts a sufficient change in NEO velocity. NASA's Deep Impact mission has demonstrated this scenario by intercepting Comet Temple 1, 5 km in diameter, with an impact relative speed of approximately 10 km/s. This paper focuses on the development of hybrid guidance navigation and control (GNC) algorithms for precision hypervelocity intercept of small sized NEOs. The spacecraft's hypervelocity and the NEO's small size are critical challenges for a successful mission as the NEO will not fill the field of view until a few seconds before intercept. The investigation needs to consider the error sources modeled in the navigation simulation such as spacecraft initial state uncertainties in position and velocity. Furthermore, the paper presents three selected spacecraft guidance algorithms for asteroid intercept and rendezvous missions. The selected algorithms are classical Proportional Navigation (PN) based guidance that use a first order difference to compute the derivatives, Three Plane Proportional Navigation (TPPN), and the Kinematic Impulse (KI). A manipulated Bennu orbit that has been changed to impact Earth will be used as a demonstrative example to compare the

  11. Extracting magnetic cluster size and its distributions in advanced perpendicular recording media with shrinking grain size using small angle x-ray scattering

    Energy Technology Data Exchange (ETDEWEB)

    Mehta, Virat; Ikeda, Yoshihiro; Takano, Ken; Terris, Bruce D.; Hellwig, Olav [San Jose Research Center, HGST a Western Digital company, 3403 Yerba Buena Rd., San Jose, California 95135 (United States); Wang, Tianhan [Department of Materials Science and Engineering, Stanford University, Stanford, California 94035 (United States); Stanford Institute for Materials and Energy Science (SIMES), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); Wu, Benny; Graves, Catherine [Stanford Institute for Materials and Energy Science (SIMES), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States); Department of Applied Physics, Stanford University, Stanford, California 94035 (United States); Dürr, Hermann A.; Scherz, Andreas; Stöhr, Jo [Stanford Institute for Materials and Energy Science (SIMES), SLAC National Accelerator Laboratory, 2575 Sand Hill Road, Menlo Park, California 94025 (United States)

    2015-05-18

    We analyze the magnetic cluster size (MCS) and magnetic cluster size distribution (MCSD) in a variety of perpendicular magnetic recording (PMR) media designs using resonant small angle x-ray scattering at the Co L{sub 3} absorption edge. The different PMR media flavors considered here vary in grain size between 7.5 and 9.5 nm as well as in lateral inter-granular exchange strength, which is controlled via the segregant amount. While for high inter-granular exchange, the MCS increases rapidly for grain sizes below 8.5 nm, we show that for increased amount of segregant with less exchange the MCS remains relatively small, even for grain sizes of 7.5 and 8 nm. However, the MCSD still increases sharply when shrinking grains from 8 to 7.5 nm. We show evidence that recording performance such as signal-to-noise-ratio on the spin stand correlates well with the product of magnetic cluster size and magnetic cluster size distribution.

  12. Presenting a Framework to Analyze Local Climate Policy and Action in Small and Medium-Sized Cities

    NARCIS (Netherlands)

    Hoppe, Thomas; van der Vegt, Arjen; Stegmaier, Peter

    2016-01-01

    Academic attention to local climate policy usually focuses on large-sized cities. Given the climate challenges ahead this seems unjustified. Small and medium-sized cities (SMCs) deserve scholarly attention as well. The main question is: What factors influence climate change policy and local climate

  13. What can we learn from studies based on small sample sizes? Comment on Regan, Lakhanpal, and Anguiano (2012).

    Science.gov (United States)

    Johnson, David R; Bachan, Lauren K

    2013-08-01

    In a recent article, Regan, Lakhanpal, and Anguiano (2012) highlighted the lack of evidence for different relationship outcomes between arranged and love-based marriages. Yet the sample size (n = 58) used in the study is insufficient for making such inferences. This reply discusses and demonstrates how small sample sizes reduce the utility of this research.

  14. Development of efficient, small particle size luminescent oxides using combustion synthesis

    Science.gov (United States)

    Shea, Lauren Elizabeth

    Luminescent materials (phosphors) find application in cathode-ray tubes (CRTs), medical and industrial equipment monitors, fluorescent lamps, xerography, and many types of flat panel displays. Many commercially available phosphors were optimized in the 1960s for high voltage (>10 kV) CRT applications. Recently, a great deal of emphasis has been placed on the development and improvement of phosphors for flat panel displays that operate at low voltages (displays demand high resolution phosphor screens which can only be realized using phosphors with smaller particle size (displays. This technique exploits the exothermic redox reaction of metal nitrates (oxidizers) with an organic fuel (reducing agent). Typical fuels include urea (CHsb4Nsb2O), carbohydrazide (CHsb6Nsb4O), or glycine (Csb2Hsb5NOsb2). Resulting powders were well-crystallized, with a large surface area and small particle size. Phosphor powders were exposed to photoluminescence excitation by high energy (254 nm, E = 4.88 eV) and low energy photons (365 nm, E = 3.4 eV and 435 nm, E = 2.85 eV) and cathodoluminescence excitation by a low-voltage (100-1000 V) electron beam. Photoluminescence (PL) techniques resulted in the measurement of spectral energy distribution and relative intensities. Phosphor efficiencies in lumens per watt (lm/W) were obtained by low-voltage cathodoluminescence measurements. The effects of processing parameters such as type of fuel, fuel to oxidizer ratio, and heating rate were studied. The combustion process was optimized based on these processing parameters in order to maximize the luminescence of the phosphor powders in the as-synthesized condition. An increase in PL intensity with increasing flame temperature of reaction was observed. Post-reaction annealing (1000-1600sp°C) increased the PL intensity and CL efficiency of the as-synthesized powders. Diffusion of the activator ions, particle growth, reduction of residual carbon impurities, disorder surrounding the activator ions

  15. Early outcome in renal transplantation from large donors to small and size-matched recipients - a porcine experimental model

    DEFF Research Database (Denmark)

    Ravlo, Kristian; Chhoden, Tashi; Søndergaard, Peter

    2012-01-01

    Kidney transplantation from a large donor to a small recipient, as in pediatric transplantation, is associated with an increased risk of thrombosis and DGF. We established a porcine model for renal transplantation from an adult donor to a small or size-matched recipient with a high risk of DGF...... and studied GFR, RPP using MRI, and markers of kidney injury within 10 h after transplantation. After induction of BD, kidneys were removed from ∼63-kg donors and kept in cold storage for ∼22 h until transplanted into small (∼15 kg, n = 8) or size-matched (n = 8) recipients. A reduction in GFR was observed...

  16. Why Do Farmers Choose to Harvest Small-Sized Timber? A Survey in YenBai Province, Northern Vietnam

    OpenAIRE

    Nguyen Nghia Bien

    2006-01-01

    Market for timber in YenBai province is quite clearly defined with two major products: small timber for pulp and wood-chips and large-sized timber for furniture to be consumed either domestically or internationally. A financial analysis shows the obvious economic advantage of growing large-sized timber over small one. However, most of private forest growers have chosen to grow small timber. The study identifies a number of factors affecting forest growers' decision to cut early their trees wh...

  17. Asymbiotic seed germination and in vitro seedling development of Paphiopedilum spicerianum: An orchid with an extremely small population in China

    Directory of Open Access Journals (Sweden)

    Ying Chen

    2015-01-01

    Full Text Available Paphiopedilum spicerianum  is listed as one of the country’s Wild Plants with Extremely Small Populations (PSESP. Procedures were developed for asymbiotic seed germination and seedling development aimed at producing seedlings for reintroduction. The highest germination was achieved in RECW with a 24 h dark cycle after pretreatment with 1% NaOCl for 40 min after 30 days from germination. However, these protocorms remained white and did not develop further. Although germination was lower under the same conditions in MSCW, it resulted in healthier and greener protocorms. Of four suitable media tested to promote seedling formation, Hyponex No 1 medium with 1.0mgl−1α-naphthalene acetic acid, 0.5gl−1 activated charcoal and 10% banana homogenate was the most effective. Advanced seedling development was seen in all six tested media during a 4 month growing period, with the highest leaf growth rate seen in the same media used for seedling formation, supplemented with 1.0mgl−16-benzyladenine added to promote leaf growth. Fluorescein diacetate (FDA tests on seeds showed that higher salt concentrations in the medium and longer duration of exposure to NaOCl reduce germination because of damaging effects on the testa and the embryo cells.

  18. A connection between extremely strong Damped Lyman-alpha Systems and Lyman-alpha Emitting Galaxies at small impact parameters

    CERN Document Server

    Noterdaeme, P; Paris, I; Cai, Z; Finley, H; Ge, J; Pieri, M M; York, D G

    2014-01-01

    We present a study of ~100 high redshift (z~2-4) extremely strong damped Lyman-alpha systems (ESDLA, with N(HI)>0.5x10^22 cm^-2) detected in quasar spectra from the Baryon Oscillation Spectroscopic Survey SDSS-III DR11. We study the neutral hydrogen, metal, and dust content of this elusive population of absorbers and confirm our previous finding that the high column density end of the N(HI) frequency distribution has a relatively shallow slope with power-law index -3.6, similar to what is seen from 21-cm maps in nearby galaxies. The stacked absorption spectrum indicates a typical metallicity ~1/20th solar, similar to the mean metallicity of the overall DLA population. The relatively small velocity extent of the low-ionisation lines suggests that ESDLAs do not arise from large-scale flows of neutral gas. The high column densities involved are in turn more similar to what is seen in DLAs associated with gamma-ray burst afterglows (GRB-DLAs), which are known to occur close to star forming regions. This indicates...

  19. The role of ejecta in the small crater populations on the mid-sized saturnian satellites

    Science.gov (United States)

    Bierhaus, Edward B.; Dones, Luke; Alvarellos, José Luis; Zahnle, Kevin

    2012-03-01

    We find evidence, by both observation and analysis, that primary crater ejecta play an important role in the small crater (less than a few km) populations on the saturnian satellites, and more broadly, on cratered surfaces throughout the Solar System. We measure crater populations in Cassini images of Enceladus, Rhea, and Mimas, focusing on image data with scales less than 500 m/pixel. We use recent updates to crater scaling laws and their constants (Housen, K.R., Holsapple, K.A. [2011]. Icarus 211, 856-875) to estimate the amount of mass ejected in three different velocity ranges: (i) greater than escape velocity, (ii) less than escape velocity and faster than the minimum velocity required to make a secondary crater (vmin), and (iii) velocities less than vmin. Although the vast majority of mass on each satellite is ejected at speeds less than vmin, our calculations demonstrate that the differences in mass available in the other two categories should lead to observable differences in the small crater populations; the predictions are borne out by the measurements we have made to date. In particular, Rhea, Tethys, and Dione have sufficient surface gravities to retain ejecta moving fast enough to make secondary crater populations. The smaller satellites, such as Enceladus but especially Mimas, are expected to have little or no traditional secondary populations because their escape velocities are near the threshold velocity necessary to make a secondary crater. Our work clarifies why the Galilean satellites have extensive secondary crater populations relative to the saturnian satellites. The presence, extent, and sizes of sesquinary craters (craters formed by ejecta that escape into temporary orbits around Saturn before re-impacting the surface, see Dobrovolskis, A.R., Lissauer, J.J. [2004]. Icarus 169, 462-473; Alvarellos, J.L., Zahnle, K.J., Dobrovolskis, A.R., Hamill, P. [2005]. Icarus 178, 104-123; Zahnle, K., Alvarellos, J.L., Dobrovolskis, A.R., Hamill, P. [2008

  20. Hypofractionated Radiotherapy for Small-sized Hepatocellular Carcinoma as Salvage Therapy: Sustained Local Control and Safety

    Energy Technology Data Exchange (ETDEWEB)

    Bae, Sun Hyun; Park, Hee Chul; Lim, Do Hoon; Lee, Jung Ae; Choi, Moon Seok; Lee, Joon Hyoek; Koh, Kwang Cheol; Paik, Seung Woon; Yoo, Byung Chul [Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul (Korea, Republic of)

    2010-11-15

    To evaluate the rate of tumor response, local control, and treatment-related complications after hypofractionated radiotherapy for recurrent hepatocelluar carcinoma (HCC) less than 5 cm in size. Among the HCC patients who were treated by radiotherapy (RT) between 2006 and 2007 after the failure of previous treatment, a total of 12 patients were treated with hypofractionated RT. The criteria for hypofractionated RT was as follows: 1) HCC less than 5 cm, 2) HCC not adjacent to a critical organ, 3) HCC without portal vein tumor thrombosis, and 4) less than 15% of normal liver volume that irradiated 50% of the prescribed dose. Hypofractionated RT was performed with 50 Gy delivered in 10 fractions, at a rate of 5 fractions per week. The evaluation of tumor response was determined by CT scans performed at 3 months after the cessation of RT, followed by the evaluation of toxicity by Common Terminology Criteria for Adverse Events version 3.0. The median follow-up period after radiotherapy was 18 months. A complete response (CR) was achieved in 5 of 12 lesions (41.7%) at CT performed at 3 months after the cessation, whereas the overall complete response was observed in 7 of 12 cases (58.3%). In-field local control rate was sustained in 83.3% of patients. All patients developed intra-hepatic metastases except for 2 patients. The overall survival rate was 90.0% at 1 year and 67.5% at 2 years, respectively. Three patients developed Grade 1 nausea during RT and 1 patient showed a progression of ascites after RT. There was no grade 3 or greater treatment-related toxicities. Hypofractionated RT for small-sized HCC as a salvage therapy showed a 58.3% CR rate and 83.3% of local control. Fifty Gy administered in 10 fractions of partial liver irradiation is considered as a tolerable dose that does not cause severe complications.

  1. Predictability in a highly stochastic system: final size of measles epidemics in small populations.

    Science.gov (United States)

    Caudron, Q; Mahmud, A S; Metcalf, C J E; Gottfreðsson, M; Viboud, C; Cliff, A D; Grenfell, B T

    2015-01-06

    A standard assumption in the modelling of epidemic dynamics is that the population of interest is well mixed, and that no clusters of metapopulations exist. The well-known and oft-used SIR model, arguably the most important compartmental model in theoretical epidemiology, assumes that the disease being modelled is strongly immunizing, directly transmitted and has a well-defined period of infection, in addition to these population mixing assumptions. Childhood infections, such as measles, are prime examples of diseases that fit the SIR-like mechanism. These infections have been well studied for many systems with large, well-mixed populations with endemic infection. Here, we consider a setting where populations are small and isolated. The dynamics of infection are driven by stochastic extinction-recolonization events, producing large, sudden and short-lived epidemics before rapidly dying out from a lack of susceptible hosts. Using a TSIR model, we fit prevaccination measles incidence and demographic data in Bornholm, the Faroe Islands and four districts of Iceland, between 1901 and 1965. The datasets for each of these countries suffer from different levels of data heterogeneity and sparsity. We explore the potential for prediction of this model: given historical incidence data and up-to-date demographic information, and knowing that a new epidemic has just begun, can we predict how large it will be? We show that, despite a lack of significant seasonality in the incidence of measles cases, and potentially severe heterogeneity at the population level, we are able to estimate the size of upcoming epidemics, conditioned on the first time step, to within reasonable confidence. Our results have potential implications for possible control measures for the early stages of new epidemics in small populations.

  2. Effects of manganese doping on the structure evolution of small-sized boron clusters

    Science.gov (United States)

    Zhao, Lingquan; Qu, Xin; Wang, Yanchao; Lv, Jian; Zhang, Lijun; Hu, Ziyu; Gu, Guangrui; Ma, Yanming

    2017-07-01

    Atomic doping of clusters is known as an effective approach to stabilize or modify the structures and properties of resulting doped clusters. We herein report the effect of manganese (Mn) doping on the structure evolution of small-sized boron (B) clusters. The global minimum structures of both neutral and charged Mn doped B cluster \\text{MnB}nQ (n  =  10-20 and Q  =  0, ±1) have been proposed through extensive first-principles swarm-intelligence based structure searches. It is found that Mn doping has significantly modified the grow behaviors of B clusters, leading to two novel structural transitions from planar to tubular and then to cage-like B structures in both neutral and charged species. Half-sandwich-type structures are most favorable for small \\text{MnB}n-/0/+ (n  ⩽  13) clusters and gradually transform to Mn-centered double-ring tubular structures at \\text{MnB}16-/0/+ clusters with superior thermodynamic stabilities compared with their neighbors. Most strikingly, endohedral cages become the ground-state structures for larger \\text{MnB}n-/0/+ (n  ⩾  19) clusters, among which \\text{MnB}20+ adopts a highly symmetric structure with superior thermodynamic stability and a large HOMO-LUMO gap of 4.53 eV. The unique stability of the endohedral \\text{MnB}\\text{20}+ cage is attributed to the geometric fit and formation of 18-electron closed-shell configuration. The results significantly advance our understanding about the structure and bonding of B-based clusters and strongly suggest transition-metal doping as a viable route to synthesize intriguing B-based nanomaterials.

  3. Variable size small targets detection using density-based clustering combined with backtracking strategy

    Science.gov (United States)

    Zhang, Haiying; Lin, Yonggui; Xiao, Fangxiong

    2016-10-01

    The series problem of infrared small target detection in heavy clutter is a challenging work in active vision. During different imaging environments the size and gray intensity of target will keep changing which lead to unstable detection. Focus on mining more robust feature of small targets and following the sequential detection framework, we propose a novel research scheme based on density-based clustering and backtracking strategy in this paper. First, point of interest is extracted by the speeded up robust feature (SURF) detector for its better performance in digging features invariant to uniform scaling, orientation and illumination changes. Second, due to the local aggregation property of target trajectory in space, a new proposed density-based clustering method is introduced to segment the target trajectory, so that the target detection problem is transformed into the extract the target trajectory. Then, In order to keep the integral and independence of the trace as much as possible, two factors: percent and are exploited to help deciding the clustering granularity. Later, the backtracking strategy is adopted to search for the target trajectory with pruning function on the basis of the consistence and continuity of the short-time target trajectory in temporal-spatial. Extended experiments show the validity of our method. Compared with the data association methods executed on the huge candidate trajectory space, the time-consuming is reduced obviously. Additional, the feature detection is more stable for the use of SURF and the false alarm suppression rate is superior to most baseline and state-of-arts methods.

  4. Are Small Classes Better? Understanding Relationships between Class Size, Classroom Processes and Pupils' Learning

    Science.gov (United States)

    Pedder, David

    2006-01-01

    Twelve years ago Blatchford and Mortimore's authoritative review of class size research appeared in this journal. They concluded that a major problem with class size research was the lack of detailed studies of complex classroom processes that might mediate class size effects on pupils' learning. This article reviews two UK class size reviews and…

  5. Determinants of the Capital Structure of Small and Medium Sized Brazilian Enterprises

    Directory of Open Access Journals (Sweden)

    Wilson Toshiro Nakamura

    2013-07-01

    Full Text Available This research investigates the determinants of the capital structure of small and medium enterprises (SMEs using a unique database that includes over 19,000 Brazilian firms and spans 13 years of data. The econometric analysis employs the System Generalized Method of Moments estimator (GMM-Sys and two strong results emerge: (a profitability is negatively related to leverage, and (b asset growth is positively related to leverage. Both results are consistent with the pecking order theory of capital structure and suggest that SMEs tend to finance their expansion with debt only after exhausting their internal resources. Additionally, we find weaker evidence for the following: (a size is positively related to leverage, which can be interpreted as evidence that larger firms have more access to credit markets; (b riskier SMEs tend to be less financially leveraged, consistent with the bankruptcy cost arguments from trade-off theories; and (c the age of the firm is negatively related to financial leverage, suggesting that older SMEs may be slightly more conservative in their financing choices. Finally, the magnitude of the coefficient of lagged leverage shows the high persistence of this variable and is compatible with the hypothesis that SMEs adjust their debt/equity ratio towards a target value, although at a low speed.

  6. TELICS—A Telescope Instrument Control System for Small/Medium Sized Astronomical Observatories

    Science.gov (United States)

    Srivastava, Mudit K.; Ramaprakash, A. N.; Burse, Mahesh P.; Chordia, Pravin A.; Chillal, Kalpesh S.; Mestry, Vilas B.; Das, Hillol K.; Kohok, Abhay A.

    2009-10-01

    For any modern astronomical observatory, it is essential to have an efficient interface between the telescope and its back-end instruments. However, for small and medium-sized observatories, this requirement is often limited by tight financial constraints. Therefore a simple yet versatile and low-cost control system is required for such observatories to minimize cost and effort. Here we report the development of a modern, multipurpose instrument control system TELICS (Telescope Instrument Control System) to integrate the controls of various instruments and devices mounted on the telescope. TELICS consists of an embedded hardware unit known as a common control unit (CCU) in combination with Linux-based data acquisition and user interface. The hardware of the CCU is built around the ATmega 128 microcontroller (Atmel Corp.) and is designed with a backplane, master-slave architecture. A Qt-based graphical user interface (GUI) has been developed and the back-end application software is based on C/C++. TELICS provides feedback mechanisms that give the operator good visibility and a quick-look display of the status and modes of instruments as well as data. TELICS has been used for regular science observations since 2008 March on the 2 m, f/10 IUCAA Telescope located at Girawali in Pune, India.

  7. Quantitative evaluation of waste prevention on the level of small and medium sized enterprises (SMEs).

    Science.gov (United States)

    Laner, David; Rechberger, Helmut

    2009-02-01

    Waste prevention is a principle means of achieving the goals of waste management and a key element for developing sustainable economies. Small and medium sized enterprises (SMEs) contribute substantially to environmental degradation, often not even being aware of their environmental effects. Therefore, several initiatives have been launched in Austria aimed at supporting waste prevention measures on the level of SMEs. To promote the most efficient projects, they have to be evaluated with respect to their contribution to the goals of waste management. It is the aim of this paper to develop a methodology for evaluating waste prevention measures in SMEs based on their goal orientation. At first, conceptual problems of defining and delineating waste prevention activities are briefly discussed. Then an approach to evaluate waste prevention activities with respect to their environmental performance is presented and benchmarks which allow for an efficient use of the available funds are developed. Finally the evaluation method is applied to a number of former projects and the calculated results are analysed with respect to shortcomings and limitations of the model. It is found that the developed methodology can provide a tool for a more objective and comprehensible evaluation of waste prevention measures.

  8. IMPORTANCE OF SMALL AND MEDIUM-SIZED ENTERPRISES IN ROMANIAN ECONOMY

    Directory of Open Access Journals (Sweden)

    BĂLĂNESCU MĂDĂLINA

    2013-08-01

    Full Text Available The market economy has reduced the number of large enterprises and has determinated the emergence ofa special class like small and medium-sized enterprises. Those companies play a special role in the nationaleconomy, especially through the fact that attract about 65% of employees in Romania, makes significantinvestments, takes approximately 30% of gross value added in the national economy, operates mainly in servicesactivity, are flexible, concerned with development and have the ability to adopt new technologies. The SMEsector has been affected by the crisis, but not in the same measure as large enterprises. This fact is demonstratedby the economic and financial indicators that I have analised, in 2011 SME beeing able to overcome the crisisand to achieve higher performance than in the years before crisis. The SME sector is considered the most activesector of the modern economy, plays a important role in the economic structure of our country, helping to ensureeconomic and social development as it is shown by the strong bond that exist between the GVA in SME sectorand total GVA added to the national economy, demonstrated in the calculations that I have made in this study.

  9. Strategies for Successful Information Technology Adoption in Small and Medium-sized Enterprises

    Directory of Open Access Journals (Sweden)

    Morteza Ghobakhloo

    2012-02-01

    Full Text Available Information Technology (IT adoption is an important field of study in a number of areas, which include small and medium-sized enterprises (SMEs. Due to the numerous advantages of IT, SMEs are trying to adopt IT applications to support their businesses. IT adoption by SMEs differs from larger organizations because of their specific characteristics, such as resources constraints. Therefore, this research aims to provide a better and clearer understanding of IT adoption within SMEs by reviewing and analyzing current IT literature. In this research, the review of literature includes theories, perspectives, empirical research and case studies related to IT adoption, in particular within SMEs from various databases such as Business Premier, Science Direct, JStor, Emerald Insight and Springer Link. The proposed model of effective IT adoption is believed to provide managers, vendors, consultants and governments with a practical synopsis of the IT adoption process in SMEs, which will in turn assist them to be successful with IT institutionalization within these businesses.

  10. Towards a Smart Encapsulation System for Small-Sized Electronic Devices: A New Approach

    Directory of Open Access Journals (Sweden)

    Sebastian-Tim Schmitz-Hertzberg

    2014-01-01

    Full Text Available Miniaturized analytical chip devices like biosensors nowadays provide assistance in highly diverse fields of application such as point-of-care diagnostics and industrial bioprocess engineering. However, upon contact with fluids, the sensor requires a protective shell for its electrical components that simultaneously offers controlled access for the target analytes to the measuring units. We therefore developed a capsule that comprises a permeable and a sealed compartment consisting of variable polymers such as biocompatible and biodegradable polylactic acid (PLA for medical applications or more economical polyvinyl chloride (PVC and polystyrene (PS polymers for bioengineering applications. Production of the sealed capsule compartments was performed by heat pressing of polymer pellets placed in individually designable molds. Controlled permeability of the opposite compartments was achieved by inclusion of NaCl inside the polymer matrix during heat pressing, followed by its subsequent release in aqueous solution. Correlating diffusion rates through the so made permeable capsule compartments were quantified for preselected model analytes: glucose, peroxidase, and polystyrene beads of three different diameters (1.4 μm, 4.2 μm, and 20.0 μm. In summary, the presented capsule system turned out to provide sufficient shelter for small-sized electronic devices and gives insight into its potential permeability for defined substances of analytical interest.

  11. Construction and Test of Full-Size Micromegas Modules for the ATLAS New Small Wheel Upgrade

    CERN Document Server

    Bortfeldt, Jonathan; The ATLAS collaboration

    2015-01-01

    In 2015 the first full size resistive-strip MicroMegas operational modules for the ATLAS New Small Wheel upgrade will be realized. The goal is to provide precision muon tracking with spatial resolution below 100 μm on trapezoidal detector areas between 2 and 3 m^2. The overall thickness of each detector modules is about 70 mm and the total number of read-out channels is of the order of 10^4. Each module consists of a quadruplet of four MicroMegas with 5 mm drift gaps intervaled with 2 read-out panels with anodes on both sides and 3 drift panels. The panels are realized as 11 mm thick stiffening sandwiches made of 10 mm thick honeycomb, 0.5 mm thick FR4 pcb material sheets as surfaces and aluminium frames. The active part of the read-out anodes consists of horizontal strips with 0.45 mm pitch. Two out of the four anode planes are built with stereo strips of identical pitch and stereo angles of ±1.5 degrees. A sequence of 128 μm height insulating pillars on the read-out planes allows the pretensioned microme...

  12. Using the IAT to predict ethnic and racial discrimination: small effect sizes of unknown societal significance.

    Science.gov (United States)

    Oswald, Frederick L; Mitchell, Gregory; Blanton, Hart; Jaccard, James; Tetlock, Philip E

    2015-04-01

    Greenwald, Banaji, and Nosek (2015) present a reanalysis of the meta-analysis by Oswald, Mitchell, Blanton, Jaccard, and Tetlock (2013) that examined the effect sizes of Implicit Association Tests (IATs) designed to predict racial and ethnic discrimination. We discuss points of agreement and disagreement with respect to methods used to synthesize the IAT studies, and we correct an error by Greenwald et al. that obscures a key contribution of our meta-analysis. In the end, all of the meta-analyses converge on the conclusion that, across diverse methods of coding and analyzing the data, IAT scores are not good predictors of ethnic or racial discrimination, and explain, at most, small fractions of the variance in discriminatory behavior in controlled laboratory settings. The thought experiments presented by Greenwald et al. go well beyond the lab to claim systematic IAT effects in noisy real-world settings, but these hypothetical exercises depend crucially on untested and, arguably, untenable assumptions. (c) 2015 APA, all rights reserved).

  13. A combimachine for harvesting of small sized trees; Pienpuun keraeilykaatoon perustuvan harvennuskoneen kehittaeminen

    Energy Technology Data Exchange (ETDEWEB)

    Lilleberg, R. [Metsaeteho, Helsinki (Finland)

    1996-12-31

    The goal of the project was to develop a combimachine suitable for the harvesting of small sized trees in first thinning. The use of such a machine could considerably decrease harvesting costs in first thinning. The basic idea with the combimachine is, that the same machine both fells the trees and transports the timber to roadside storages. A forwarder was equipped with a lightweight felling device, which also can do the crosscutting and loading. When harvesting undelimbed timber the forwarder could be equipped with a load-compressing device. During the spring 1995 a trial was made with a combimachine in a first thinning stand of pine. An ordinary forwarder was equipped with the `Naarva-grapple` a device for felling, crosscutting and loading. The aim was to test how the felling device is working, to examine time expenditure for two different working methods and to collect data for the further development of the machine. The trial showed a need to add a delimbing feature to the Naarva-grapple. The need for delimbing is based on the fact, obtained during the trial, that productivity in transport of delimbed timber was over 30 % higher than in transport of undelimbed pieces. A device capable of delimbing was designed, and it was ready for a prototype test in December 1995. The idea worked, but also showed a lot of details which have to be redesigned, before the device is ready for manufacturing and marketing

  14. Subspace Leakage Analysis and Improved DOA Estimation With Small Sample Size

    Science.gov (United States)

    Shaghaghi, Mahdi; Vorobyov, Sergiy A.

    2015-06-01

    Classical methods of DOA estimation such as the MUSIC algorithm are based on estimating the signal and noise subspaces from the sample covariance matrix. For a small number of samples, such methods are exposed to performance breakdown, as the sample covariance matrix can largely deviate from the true covariance matrix. In this paper, the problem of DOA estimation performance breakdown is investigated. We consider the structure of the sample covariance matrix and the dynamics of the root-MUSIC algorithm. The performance breakdown in the threshold region is associated with the subspace leakage where some portion of the true signal subspace resides in the estimated noise subspace. In this paper, the subspace leakage is theoretically derived. We also propose a two-step method which improves the performance by modifying the sample covariance matrix such that the amount of the subspace leakage is reduced. Furthermore, we introduce a phenomenon named as root-swap which occurs in the root-MUSIC algorithm in the low sample size region and degrades the performance of the DOA estimation. A new method is then proposed to alleviate this problem. Numerical examples and simulation results are given for uncorrelated and correlated sources to illustrate the improvement achieved by the proposed methods. Moreover, the proposed algorithms are combined with the pseudo-noise resampling method to further improve the performance.

  15. Gastrointestinal nematodes in grazing dairy cattle from small and medium-sized farms in southern Poland.

    Science.gov (United States)

    Piekarska, J; Płoneczka-Janeczko, K; Kantyka, M; Kuczaj, M; Gorczykowski, M; Janeczko, K

    2013-11-15

    This study aimed to estimate the prevalence of gastrointestinal nematodes and the intensity of infection in grazing dairy cattle from small and medium-sized farms in southern Poland. The level of antibodies against Ostertagia ostertagi in the bulk tank milk (BTM) from the animals was also assessed. Rectal fecal samples collected from 361 cows on 20 farms were examined using Willis-Schlaaf flotation and the McMaster method. BTM samples were tested for the presence of O. ostertagi antibodies using ELISA. Multiplex PCR was used to identify the third-stage larvae (L3) of gastrointestinal nematodes derived from the culture of pooled fecal samples from sampled farms. Gastrointestinal nematode eggs were found in the samples from 18 of the 20 herds with a prevalence range from 20.4 to 94.5%. The average number of eggs excreted in the feces of the herds was 200 eggs per gram (EPG). Antibodies to O. ostertagi were found in 20 of the examined herds (100%), of which 6 had optical density ratios (ODR) greater than 0.5. PCR results showed the presence of three nematode species: Ostertagia ostertagi, Cooperia oncophora and Oesophagostomum radiatum.

  16. The Sustainable Strategy for Small and Medium Sized Enterprises: The Relationship between Mission Statements and Performance

    Directory of Open Access Journals (Sweden)

    Ethem Duygulu

    2016-07-01

    Full Text Available The study aims to contribute to the literature by empirically examining the relationship between small and medium sized enterprises’ (SMEs mission statements and their performance in sustainable strategy formulation. Although it seems that there is a relatively vast amount of research with regard to mission statements of companies, very few studies have focused on the relationship between mission statements and performance. When these few studies are taken into consideration, it is difficult to reach any overall conclusion since their findings are mixed and inconclusive. To achieve this aim, 3034 SMEs operating in organized industrial zones in Turkey were examined via a survey approach. In order to investigate the relationships among the variables, nine categories of mission statements as independent variables and four performance indicators (financial, market, production, and overall as dependent variables were analyzed through logistic regression. This study identified three mission components, (1 survival, growth, and profit; (2 philosophy and values; and (3 public image, as the common independent variables in explaining the performance of SMEs. Survival, growth, and profit is the most frequently observed mission component regardless of the subsector differentiation in the entire sample, which reflects the significance of business sustainability for SMEs in the Turkish manufacturing context. Besides, among all performance indicators, SMEs’ market performance was found to be the lowest when compared to other performance indicators (financial, production, overall. Although the firms were placed in different manufacturing subsectors, similar mission statements were highlighted so that the discourse similarity might be considered as evidence of isomorphism characteristics for SMEs.

  17. Service Pyramid Concept of Knowledge Intensive Business Services in the Small and Medium Sized Enterprises Sector

    Directory of Open Access Journals (Sweden)

    Sándor Nagy

    2013-12-01

    Full Text Available The activity of service companies is more complex today than before the use of Information and Communication Technology (ICT became widespread in business. Fewer service companies can be found on the market based solely on physical customer interaction; however, they have been replaced with standardized and automated services. This structural change can be observed particularly among Knowledge Intensive Business Services (KIBS companies where the use of ICT is not simply a market requirement, but a competition tool, as well. Without the application of any ICT instrument, a KIBS company could not meet market expectations, and furthermore, business developments are mainly ICT-based. On the other hand, companies need to develop their businesses more and more, as KIBS companies which are not able to differentiate themselves as trustworthy on the business services market will disappear. ‘Just another business service company’ cannot really sell today. This is applicable to a greater extent to Small and Medium Sized Enterprises (SME, where ICT has opened market opportunities that have never existed for them before. The aim of this paper is to highlight the new features of KIBS business activities in the SME sector and the related research questions.

  18. Outcomes of robot-assisted versus laparoscopic repair of small-sized ventral hernias.

    Science.gov (United States)

    Chen, Y Julia; Huynh, Desmond; Nguyen, Scott; Chin, Edward; Divino, Celia; Zhang, Linda

    2017-03-01

    The aim of the study is to investigate the outcomes of the da Vinci robot-assisted laparoscopic hernia repair of small-sized ventral hernias with circumferential suturing of the mesh compared to the traditional laparoscopic repair with trans-fascial suturing. A retrospective review was conducted of all robot-assisted umbilical, epigastric and incisional hernia repairs performed at our institution between 2013 and 2015 compared to laparoscopic umbilical or epigastric hernia repairs. Patient characteristics, operative details and postoperative complications were collected and analyzed using univariate analysis. Three primary minimally invasive fellowship trained surgeons performed all of the procedures included in the analysis. 72 patients were identified during the study period. 39 patients underwent robot- assisted repair (21 umbilical, 14 epigastric, 4 incisional), and 33 patients laparoscopic repair (27 umbilical, 6 epigastric). Seven had recurrent hernias (robot: 4, laparoscopic: 3). There were no significant differences in preoperative characteristics between the two groups. Average operative time was 156 min for robot-assisted repair and 65 min for laparoscopic repair (p robot group [3.07 cm (1-9 cm)] than that for the laparoscopic group [2.02 cm (0.5-5 cm)] (p robot-assisted technique versus the standard laparoscopic repair.

  19. Construction and Test of Full-Size Micromegas Modules for the ATLAS New Small Wheel Upgrade

    CERN Document Server

    Bortfeldt, Jonathan; The ATLAS collaboration

    2015-01-01

    In 2015 the first full size resistive-strip Micromegas operational modules for the ATLAS New Small Wheel upgrade will be realized. The goal is to provide precision muon tracking with spatial resolution below 100$\\mu$m on trapezoidal four-layer detector modules with areas between 2 and 3m$^2$. This poses stringent limits on the overall accuracy of the modules with respect to strip positioning and planarity. The overall thickness of each modules is about 70mm and the total number of readout channels is on the order of $1.5\\cdot10^4$ per module. Each module is a quadruplet of four resistive strip Micromegas layers with 5mm drift gap. It is constructed from two readout panels with readout anodes on both sides and three drift panels, that carry the cathode structure. The panels are realized as sandwich structures of aluminum honeycomb, framed by aluminum bars and faced by printed circuit boards, carrying readout or cathode structures. The readout structure consists of strips with 0.43mm pitch and up to 2m length. ...

  20. Downstream passage of fish larvae and eggs through a small-sized reservoir, Mucuri river, Brazil

    Directory of Open Access Journals (Sweden)

    Paulo S. Pompeu

    2011-12-01

    Full Text Available In South America, one important symptom of the failure of fish passages to sustain fish migratory recruitment is the inability of eggs and larvae to reach the nurseries. This is especially so when the breeding areas are located upstream of a reservoir, and the floodplain is downstream of the dam. Therefore, the transport of fish larvae and eggs across reservoir barriers is a key factor in the development of effective conservation strategies. In this paper, we evaluate the potential for migratory fish larvae and egg transportation across a small size reservoir in eastern Brazil. We sampled fish daily between 15th October 2002 and 15th February 2003 (spawning period in the Mucuri River, immediately upstream of the reservoir and downstream of the Santa Clara Power Plant dam. Our study was the first to indicate the possibility of successful larval passage through the reservoir of a hydroelectric reservoir and dam in South America, and showed that the passage of migratory fish larvae was associated significantly with residence time of water in the reservoir. The relatively short water residence time and elevated turbidity of the Santa Clara's reservoir waters during the rainy season certainly contributed to the successful passage, and can be considered as key factors for a priori evaluations of the feasibility of a downstream larval passage.

  1. A Framework for Integrating Usability Practices into Small-Sized Software Development Organizations

    Directory of Open Access Journals (Sweden)

    Lulwa Alyahyan

    2016-09-01

    Full Text Available Usability now appears to be a highly important attribute for software quality; it is a critical factor that needs to be considered by every software-development organization when developing software to improve customer satisfaction and increase competition in the market. There exists a lack of a reference model or framework for small-sized software-development organizations to indicate which usability practices should be implemented, and where in the system-development life cycle they need to be considered. We offer developers who have the objective of integrating usability practices into their development life cycle a framework that characterizes 10 selected user-centered design (UCD methods in relation to five relevant criteria based on some ISO factors that have an effect on the selection of methods (ISO/TR16982. The selection of the methods for inclusion in the framework responds to these organizations’ needs; and we selected basic methods that are recommended, cost-effective, simple to plan and apply, and easy to learn by developers; and which can be applied when time, resources, skills, and expertise are limited. We favor methods that are generally applicable across a wide range of development environments. The selected methods are organized in the framework according to the stages in the development process where they might be applied. The only requirement for the existing development life cycle is that it to be based on an iterative approach.

  2. Bayesian forecasting of the recurrent earthquakes and its predictive performance for a small sample size

    Science.gov (United States)

    Nomura, S.; Ogata, Y.

    2010-12-01

    This study is concerned with the probability forecast by the Brownian Passage Time (BPT) model especially in case where only a few records of recurrent earthquakes from an active fault are available. We adopt the Bayesian predictive distribution that takes the relevant prior information and all possibilities for model parameters into account. We utilize the size of single-event displacements U and the slip rate V across the segment to calculate the mean recurrence time T=U/V that the past recurrence intervals are distributed around as Figure 1. We then make use of the best fitted prior distribution for the BPT variation coefficient (the shape parameter, α) selected by the Akaike Bayesian information criterion (ABIC), while the ERC uses the same common estimate α=0.24. Applying this prior distribution, we can see that α takes various values among the faults but has some locational tendencies from Figure 2. For example, α values tend to be higher in the center of Honshu island where the faults are densely populated. We compare the goodness of fit and probability forecasts between the conventional models and our proposed model by historical or simulated datasets. The Bayesian predictor shows very stable and superior performance for small samples or variant recurrence times. Figure 1: The relation between mean recurrence time from slip data and past recurrence intervals with error bars. Figure 2: The map of active faults in land and subduction-zones in Japan, whose colors show the Bayes estimates of variation coefficient α.

  3. Use of recycling through medium size granular filters to treat small food processing industry effluents.

    Science.gov (United States)

    Ménoret, C; Boutin, C; Liénard, A; Brissaud, F

    2002-01-01

    Currently there are no suitable wastewater treatment systems for effluents from small food processing industries (dairy, cheese, wine production). Such raw sewages are characterized by high organic matter concentrations (about 10 g COD L-1) and relatively low daily volumes (about 2 m3). An adaptation of attached-growth cultures on fine media processes, known to be easy and inexpensive to use, could fit both the technical and economical context of those industries. Coarser filter particle size distributions than those normally used allow a better aeration and reduce clogging risk. The transit time of the effluent through the porous filter materials is shortened and requires recycling to increase the contact time between the biomass and the substrate. A pilot plant was built to compare the efficiency of two kinds of filter materials, gravel (2-5 mm) and pozzolana (3-7 mm). Two measurement campaigns were undertaken on a full-scale unit dealing with cheese dairy effluents. Both pilot-scale and full-scale plants show high COD removal rates (> 95%). Pilot-scale experiments show that accumulation of organic matter leads to the clogging of the recycling filter. To prevent early clogging, a better definition of feeding cycles is needed.

  4. Energy conserved and costs saved by small and medium-size manufacturers, 1988--1989

    Energy Technology Data Exchange (ETDEWEB)

    Kirsch, F.W.

    1991-05-01

    Energy Analysis and Diagnostic Centers (EADCs) provided energy-conserving and cost saving assistance in 339 small and medium-size manufacturing plants nationwide during 1988-89. This report presents the results of what was recommended to those manufacturers, the record of what was implemented by them, and an analysis of the financial rewards gained by them. It also includes an accounting of the financial returns to the federal government, derived from taxes upon the cost savings, or incremental income, of the manufacturers who implement the EADCs` recommendations. EADCs collect implementation data within a year of the energy audit, and for these results that time period extended through 1990. The EADCs are located at accredited engineering departments of universities and staffed by faculty and students. At present there are 18 EADCs serving manufacturers in 37 states; of these, two were established as a result of the 1989 competition, and five more were chosen competitively in 1990. Most of the results in this report were generated by 11 EADCs (named in the Appendix); two others withdrew voluntarily after completing only 10 energy audits during 1988-89. Primary responsibility for selecting, training, evaluating, and managing the EADCs belongs to the Industrial Technology and Energy Management (ITEM) division of University City Science Center (UCSC). The Department of Energy`s Office of Industrial Technologies sponsors the EADC program through an agreement with UCSC.

  5. CRITICAL FACTORS IN OUTSOURCING OF ACCOUNTING FUNCTIONS IN MALAYSIAN SMALL MEDIUM-SIZED ENTERPRISES (SMEs

    Directory of Open Access Journals (Sweden)

    Magiswary Dorasamy

    2010-01-01

    Full Text Available The challenges that business face in sustaining competitive advantage in the corporate world have become a major concern. Businesses are adopting cutting-edge technologies and best practices to cope with rapid, global changes. Various business functions are being reengineered for this purpose. Accounting functions play an important role in helping businesses to maintain competitive advantage. However, some small and medium-sized enterprises (SMEs face problems handling fundamental accounting functions. This is predominantly because of their lack of expertise; accounting functions require not only knowledge of generally accepted accounting rules or tax regulations but also the expertise needed to apply the rules in a given business environment (Everaert, Sarens and Rommel, 2006. This paper offers some insight on the outsourcing of accounting functions as there is paucity of data in this area in the context of Malaysia. Essentially, it presents empirical evidence regarding Malaysian SMEs' accounting outsourcing practices. A survey of SMEs was conducted to identify the overall outsourcing landscape as it relates to accounting and third-party organisations. The factors that contribute to the decision to outsource accounting functions are analysed. The study reveals a significant relationship between outsourcing accounting functions and two contributing factors, risks and operation management.

  6. Regularization Methods for Fitting Linear Models with Small Sample Sizes: Fitting the Lasso Estimator Using R

    Directory of Open Access Journals (Sweden)

    W. Holmes Finch

    2016-05-01

    Full Text Available Researchers and data analysts are sometimes faced with the problem of very small samples, where the number of variables approaches or exceeds the overall sample size; i.e. high dimensional data. In such cases, standard statistical models such as regression or analysis of variance cannot be used, either because the resulting parameter estimates exhibit very high variance and can therefore not be trusted, or because the statistical algorithm cannot converge on parameter estimates at all. There exist an alternative set of model estimation procedures, known collectively as regularization methods, which can be used in such circumstances, and which have been shown through simulation research to yield accurate parameter estimates. The purpose of this paper is to describe, for those unfamiliar with them, the most popular of these regularization methods, the lasso, and to demonstrate its use on an actual high dimensional dataset involving adults with autism, using the R software language. Results of analyses involving relating measures of executive functioning with a full scale intelligence test score are presented, and implications of using these models are discussed.

  7. Weighted piecewise LDA for solving the small sample size problem in face verification.

    Science.gov (United States)

    Kyperountas, Marios; Tefas, Anastasios; Pitas, Ioannis

    2007-03-01

    A novel algorithm that can be used to boost the performance of face-verification methods that utilize Fisher's criterion is presented and evaluated. The algorithm is applied to similarity, or matching error, data and provides a general solution for overcoming the "small sample size" (SSS) problem, where the lack of sufficient training samples causes improper estimation of a linear separation hyperplane between the classes. Two independent phases constitute the proposed method. Initially, a set of weighted piecewise discriminant hyperplanes are used in order to provide a more accurate discriminant decision than the one produced by the traditional linear discriminant analysis (LDA) methodology. The expected classification ability of this method is investigated throughout a series of simulations. The second phase defines proper combinations for person-specific similarity scores and describes an outlier removal process that further enhances the classification ability. The proposed technique has been tested on the M2VTS and XM2VTS frontal face databases. Experimental results indicate that the proposed framework greatly improves the face-verification performance.

  8. Barriers to energy efficiency improvement. Empirical evidence from small-and-medium-sized enterprises in China

    Energy Technology Data Exchange (ETDEWEB)

    Kostka, Genia; Moslener, Ulf; Andreas, Jan G.

    2012-07-01

    This paper analyzes barriers for energy efficiency investments for small-and medium-sized enterprises (SMEs) in China. Based on a survey of 480 SMEs in Zhejiang Province, this study assesses financial, informational, and organizational barriers for energy efficiency investments in the SME sector. The conventional view has been that the lack of appropriate financing mechanisms particularly hinders SMEs to adopt cost-effective energy efficiency measures. As such, closing the financing gap for SMEs is seen as a prerequisite in order to promote energy efficiency in the sector. The econometric estimates of this study, however, suggest that access to information is an important determinant of investment outcomes, while this is less clear with respect to financial and organizational factors. More than 40 percent of enterprises in the sample declared that that they are not aware of energy saving equipments or practices in their respective business area, indicating that there are high transaction costs for SMEs to gather, assess, and apply information about energy saving potentials and relevant technologies. One implication is that the Chinese government may assume an active role in fostering the dissemination of energy-efficiency related information in the SME sector. (orig.)

  9. 78 FR 61443 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2013-10-03

    ...-Disabled Veteran-Owned small businesses, Participants in SBA's 8(a) Business Development Program, or Women...-Disabled Veteran-Owned small businesses, Women-Owned Small Businesses, or Participants in the SBA's 8(a... From the Federal Register Online via the Government Publishing Office SMALL...

  10. Repair of Small and Medium Size Umbilical Hernias with the "Proceed Ventral Patch" in the Preperitoneal Position.

    Science.gov (United States)

    Zarmpis, Nikolaos; Wassenberg, Dirk; Ambe, Peter C

    2015-11-01

    Small- and medium-sized ventral hernias including umbilical hernias can be repaired using prosthetic patches placed in the peritoneum. However, bowel-associated complications secondary to intraperitoneally placed hernia patches have been reported. Herein, we report the outcome of small and medium umbilical hernia closure with prosthetic hernia patches in the preperitoneal space. Prospectively collected data of patients undergoing repair of small- and medium-sized umbilical hernias with the proceed ventral patch in a primary care hospital in Germany was retrospectively analyzed. A total of 39 cases, including 11 female and 28 male patients, were managed with prosthetic patches in the preperitoneal position. Small-sized patches were implantated in 16 cases, whereas medium-sized patches were used in 23 cases. The median duration of surgery was 40 minutes. The median length of hospital stay was four days. Four minor complications were recorded (10.3%) and the rate of recurrence was 2.6 per cent within a follow-up period of up to 30 months. Small and medium size umbilical hernias can be effectively closed with prosthetic patches placed in the preperitoneal space without risk of serious bowel associated complications.

  11. Organisational culture as a part in the development of open innovation - the perspective of small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Szymańska Katarzyna

    2016-05-01

    Full Text Available The ability to introduce various concepts and business models is nowadays a prerequisite of creating a competitive advantage. This is to a large extent closely linked to the ability of enterprises to create, implement and disseminate a variety of innovative solutions. Today the use of open innovation is a necessity. This applies not only to large organisations, but also to small and medium-sized enterprises. In order to implement open innovation, small and medium-sized enterprises need to effectively manage their own growth through the preparation of appropriate strategies and the development of a model that encompasses all changes, taking into account a number of factors related to the growth dynamics of this sector. It is understood that an appropriate organisational culture plays an important role in the implementation of innovation in the sector of small and medium-sized enterprises. There are many indications that a cultural mismatch and misunderstanding are the main reasons for major problems related to the low level of implementation of innovation by small and medium-sized enterprises. The aim of the paper is to outline the issue of the impact of organisational culture on the development of the concept of open innovation in the sector of small and medium-sized enterprises.

  12. On the small and medium-sized enterprise development strategy%论中小企业发展战略

    Institute of Scientific and Technical Information of China (English)

    陈少华; 吴丹洁

    2013-01-01

    中小企业是是我国国民经济建设一支重要的战略力量,是构建市场经济的主题。研究国家对促进中小企业发展制定的政策措施,对中小企业在新的历史发展阶段、在世界经济环境激烈的竞争中加快发展步伐具有重大的意义。本文以中小企业为研究对象,结合中小企业发展环境、发展现状,对中小企业发展现状进行研究与探讨。阐述了中小企业发展理论、历史进程、中小企业的作用以及存在的问题,阐释了政府支持中小企业发展的理论依据,及近期国内促进中小企业发展的优惠政策措施,分析中小企业现阶段的环境,提出促进中小企业发展的政策措施以及改善的建议。%The small and medium-sized enterprise is our country national economy construction is an important strategic forces, is the construction of market economy subject. Study on promoting the development of SMEs policy measures, to the small and medium-sized enterprise in the new historical stage of development, in the fierce competition in the world economic environment to speed up the pace of development is of great significance. In this paper, small and medium-sized enterprises as the research object, combining with the current situation of small and medium-sized enterprise development environment, development, research and discussion on the development of small and medium enterprises. The small and medium-sized enterprise development theory, historical process, the role of small and medium-sized enterprises and the existing problems, explains the theoretical basis for the government to support the development of SMEs, and promote the development of small and medium-sized enterprises in China's preferential policies and measures, the analysis of small and medium enterprises at the present stage of environment, put forward to promote the development of small and medium enterprises policy measures and suggestions for

  13. Extreme secular excitation of eccentricity inside mean motion resonance. Small bodies driven into star-grazing orbits by planetary perturbations

    Science.gov (United States)

    Pichierri, Gabriele; Morbidelli, Alessandro; Lai, Dong

    2017-09-01

    Context. It is well known that asteroids and comets fall into the Sun. Metal pollution of white dwarfs and transient spectroscopic signatures of young stars like β-Pic provide growing evidence that extra solar planetesimals can attain extreme orbital eccentricities and fall into their parent stars. Aims: We aim to develop a general, implementable, semi-analytical theory of secular eccentricity excitation of small bodies (planetesimals) in mean motion resonances with an eccentric planet valid for arbitrary values of the eccentricities and including the short-range force due to General Relativity. Methods: Our semi-analytic model for the restricted planar three-body problem does not make use of series expansion and therefore is valid for any eccentricity value and semi-major axis ratio. The model is based on the application of the adiabatic principle, which is valid when the precession period of the longitude of pericentre of the planetesimal is much longer than the libration period in the mean motion resonance. In resonances of order larger than 1 this is true except for vanishingly small eccentricities. We provide prospective users with a Mathematica notebook with implementation of the model allowing direct use. Results: We confirm that the 4:1 mean motion resonance with a moderately eccentric (e' ≲ 0.1) planet is the most powerful one to lift the eccentricity of planetesimals from nearly circular orbits to star-grazing ones. However, if the planet is too eccentric, we find that this resonance is unable to pump the planetesimal's eccentricity to a very high value. The inclusion of the General Relativity effect imposes a condition on the mass of the planet to drive the planetesimals into star-grazing orbits. For a planetesimal at 1 AU around a solar mass star (or white dwarf), we find a threshold planetary mass of about 17 Earth masses. We finally derive an analytical formula for this critical mass. Conclusions: Planetesimals can easily fall into the central star

  14. Prey size spectra and prey availability of larval and small juvenile cod

    DEFF Research Database (Denmark)

    Munk, Peter

    1997-01-01

    The aim of the present study is to describe the prey preference characteristics of cod larvae and assess preference variability in relation to species and size composition of copepod prey. A further aim is to examine the hypothesis that dietary prey size spectra remain the same during the larval...... stage when viewed on a relative predator/prey size scale. The study is based on stomach analysis of larval/juvenile cod in the size range 10-35 mm from nursery grounds in the North Sea. Stomach contents (species, size) were compared to environmental composition and preference indices were calculated....... Prey size spectra had the expected relationship to larval cod size, and preference for given copepod species could be ascribed to their relative size; Additional species-specific preferences were evident, for example the larger Pseudocalanus and the larger Calanus spp. were highly preferred. Available...

  15. 78 FR 37409 - Small Business Size Standards: Finance and Insurance and Management of Companies and Enterprises

    Science.gov (United States)

    2013-06-20

    ... Exchanges $7.0 $35.5. 523910 Miscellaneous Intermediation $7.0 $35.5. 523920 Portfolio Management $7.0 $35.5... feedback on its methodology and other size standards issues. In addition, SBA presented its size standards... how interested parties can provide SBA with input and feedback on size standards review. Moreover,...

  16. Why "Small" Can Be Better: An Exploration of the Relationships between Class Size and Pedagogical Practices

    Science.gov (United States)

    Harfitt, Gary James

    2013-01-01

    A central issue in the class size debate is that while cutting class size might lead to improved teaching and learning, it is also possible that it may not if teachers do not seek to exploit the advantages of a smaller class size through an alternative pedagogy. Research suggests that teachers do not change their pedagogy when moving from large…

  17. Analysing a method for small and medium sized companies to rate oil quality during immersion frying

    Directory of Open Access Journals (Sweden)

    Efraín Hisnardo Rojas Uribe

    2011-01-01

    Full Text Available  This work studied the deterioration of commercial Frytol oil in controlled frying conditions using the anisidine index (AI as standard evaluation method. The effect of temperature and time was studied at 170°C for up to 10 hours and at 200°C for up to 6 hours in the presence of factors which speeded up oil deterioration: 1% and 8% water based on the mass of oil and non-lipid material, 1% and 6% based on the mass of oil. Air flow rate was kept constant at 25 L h-1. The relationship between AI, colour and viscosity was studied to evaluate the technical viability of measuring these variables as a function of time to be used as a method for rating oil deterioration by small and medium sized enterprises (SME. Oil deterioration was higher and faster at maximum study interval values for each experimental factor, although only the effect of temperature was significant (p2=0.558 and R2=0.526, respectively, colour depending on frying temperature. Viscosity measured at 30°C had the highest coefficient of determination (R2=0.809 and was independent of frying temperature. Viscosity is thus a variable which can be used for determining frying oil deterioration in SME as a consequence of a significant change from 10 cP to 45 cP which is closer to frying oil deterioration limit (AI 156. It can facilitate determination and lower associated costs, thereby improving product quality and customer confidence in them. 

  18. THE PREMISES OF STRATEGIC MARKETING PLANNING IMPLEMENTATION WITHIN SMALL AND MEDIUM SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Popescu Andrei

    2011-07-01

    Full Text Available The main purpose of the present paper is to identify the framework and the necessary conditions for the small and medium sized enterprises (SMEs to be able to adopt the strategic marketing planning. Also, the paper aims to underline the importance of the strategic marketing planning and the manner in which the SMEs can adopt, implement and operationalize the strategic marketing planning instruments, whose correct understanding and usage ensure the capacity to generate competitive advantage, the key element both from the perspective of the fierce competition and the perspective of the future development of the SMEs. Within SMEs the implementation of marketing becomes an evident requirment, mostly due to the relationship that these have with the market, thus, leading towards market orientation of the activities, a new approach developed by the marketing vision on managing the activities from these types of organizations. Regarded upon, from the marketing perspective, the activities from the SMEs, especially the marketing activities, cannot take place randomly. Resource allocation, a characteristic of these types of organizations, and the objectives with regards to superior customer needs satisfaction and economic efficiency maximization, claim thorough plannification and deployment of the activities in a sequence that represents the implementation of a strategy previously assumed. Within this framework, the strategic marketing planning appears as a complex process employing all scientific instruments that comprise segmentation, positioning and marketing mix. Utilizing the strategic marketing planning within SMEs depends to further extend on marketing integration; process directly related with a series of factors such as the nature of the market, development stage, product type, management quality and the influences of the marketing department of the SME. The implications onto the marketing activities from SMEs are reflected upon each strategic

  19. [Problems of implementing integration management at company level in small and medium-sized enterprises].

    Science.gov (United States)

    Hetzel, C; Flach, T; Weber, A; Schian, H-M

    2006-05-01

    At company level responsibility increases for the employment of workers with health-related problems or disabilities, but realisation in small and medium-sized enterprises (SME) is lacking. Therefore a model is developed based on theory and a survey. Minimum requirements for "betriebliches Eingliederungsmanagement" (integration management at company level) according to section 84 (2) SGB IX Book 9 of the German Social Code, the main products of the international movement "disability management", a description of roles for realisation and the main sources of employers' support are described. Although external supporting of SMEs is unquestioned, it is expensive and retards own initiative and own activity counting solely on this. Only by developing a minimum of SME's awareness, acceptance and competence, this will open up to (currently suboptimal) external support. Goal is identifying SME managers' attitudes, activities, proposals and expectations referring integration management at company level to derive concepts of SME's support. 13 interviews are analysed by qualitative content analysis identifying the following barriers: information deficit, absence of priority, limited possibilities for transitional work, cost, partially limited workers' self-responsibility, illness as a "tabes" subject. Possibilities overcoming these barriers are delineated. On that basis a model is presented: pragmatically for realisation, a company contact person with minimum competence, uniform external support, institutional partners' integration and quality assurance according to disability management. Interlocking SME world and social insurance world means first to support SME's awareness, acceptance and competence, second to create for SME a central contact in the "rehabilitation jungle" and third to develop SME-suitable premiums according to section 84 (3) SGB IX, Book 9 of the German social code.

  20. Size And Shape of Detergent Micelles Determined By Small-Angle X-Ray Scattering

    Energy Technology Data Exchange (ETDEWEB)

    Lipfert, Jan; Columbus, Linda; Chu, Vincent B.; Lesley, Scott A.; Doniach, Sebastian; /Stanford U., Phys. Dept. /Stanford U., Appl. Phys. Dept. /SLAC, SSRL /Pasteur Inst., Paris /Scripps Res. Inst. /Novartis Res. Found.

    2009-04-29

    We present a systematic analysis of the aggregation number and shape of micelles formed by nine detergents commonly used in the study of membrane proteins. Small-angle X-ray scattering measurements are reported for glucosides with 8 and 9 alkyl carbons (OG/NG), maltosides and phosphocholines with 10 and 12 alkyl carbons (DM/DDM and FC-10/FC-12), 1,2-dihexanoyl-sn-glycero-phosphocholine (DHPC), 1-palmitoyl-2-hydroxy-sn-glycero-3-[phospho-rac-(1-glycerol)] (LPPG), and 3-[(3-cholamidopropyl)dimethylammonio]-1-propane sulfonate (CHAPS). The SAXS intensities are well described by two-component ellipsoid models, with a dense outer shell corresponding to the detergent head groups and a less electron dense hydrophobic core. These models provide an intermediate resolution view of micelle size and shape. In addition, we show that Guinier analysis of the forward scattering intensity can be used to obtain an independent and model-free measurement of the micelle aggregation number and radius of gyration. This approach has the advantage of being easily generalizable to protein-detergent complexes, where simple geometric models are inapplicable. Furthermore, we have discovered that the position of the second maximum in the scattering intensity provides a direct measurement of the characteristic head group-head group spacing across the micelle core. Our results for the micellar aggregation numbers and dimensions agree favorably with literature values as far as they are available. We de novo determine the shape of FC-10, FC-12, DM, LPPG, and CHAPS micelles and the aggregation numbers of FC-10 and OG to be ca. 50 and 250, respectively. Combined, these data provide a comprehensive view of the determinants of micelle formation and serve as a starting point to correlate detergent properties with detergent-protein interactions.

  1. Reliable calculation in probabilistic logic: Accounting for small sample size and model uncertainty

    Energy Technology Data Exchange (ETDEWEB)

    Ferson, S. [Applied Biomathematics, Setauket, NY (United States)

    1996-12-31

    A variety of practical computational problems arise in risk and safety assessments, forensic statistics and decision analyses in which the probability of some event or proposition E is to be estimated from the probabilities of a finite list of related subevents or propositions F,G,H,.... In practice, the analyst`s knowledge may be incomplete in two ways. First, the probabilities of the subevents may be imprecisely known from statistical estimations, perhaps based on very small sample sizes. Second, relationships among the subevents may be known imprecisely. For instance, there may be only limited information about their stochastic dependencies. Representing probability estimates as interval ranges on has been suggested as a way to address the first source of imprecision. A suite of AND, OR and NOT operators defined with reference to the classical Frochet inequalities permit these probability intervals to be used in calculations that address the second source of imprecision, in many cases, in a best possible way. Using statistical confidence intervals as inputs unravels the closure properties of this approach however, requiring that probability estimates be characterized by a nested stack of intervals for all possible levels of statistical confidence, from a point estimate (0% confidence) to the entire unit interval (100% confidence). The corresponding logical operations implied by convolutive application of the logical operators for every possible pair of confidence intervals reduces by symmetry to a manageably simple level-wise iteration. The resulting calculus can be implemented in software that allows users to compute comprehensive and often level-wise best possible bounds on probabilities for logical functions of events.

  2. The Effective Use of Facebook by Small and Medium-Sized Enterprises Operating in Slovakia

    Directory of Open Access Journals (Sweden)

    František Pollák

    2016-06-01

    Full Text Available Purpose – The aim of this study was to identify and then interpret the basic preconditions for effective use of the social networking site Facebook as a marketing communication platform for small and medium-sized enterprises (SMEs operating in a selected Central European market. Design/Methodology/Approach – In order to achieve the objective, as well as partial targets, this contribution can be seen as a summary of two autonomous and extensive analyses. The context necessary for the fulfillment of the main objective was analyzed based on secondary data on hundreds of company profiles (of local SMEs, operating predominantly in the service sector and conducting their business activities in a business-to-consumer (B2C environment managed by a specific marketing agency operating on the Slovak market. The collected data were subsequently subjected to a thorough statistical testing based on monitored parameters. Findings and implications – From the perspective of the main findings, basic recommendations for the efficient use of selected marketing communication tools on the social networking site Facebook are described in terms of improving the expected user interactions. Limitations – We consider the mainly local nature of the data sources to be the biggest limitation in the research process. Due to the local nature of this study, however, this limitation has no significant effect on the quality of the research. Originality – The findings and information presented in this contribution can help improve our understanding of issues related to the effective implementation of resources (time and finances by entities using selected marketing tools, particularly marketing communication in the context of the social networking site Facebook for the purpose of promotion and branding.

  3. Factors preceding CRM readiness in small- and medium-sized tourism enterprises

    Directory of Open Access Journals (Sweden)

    Dinesh Vallabh

    2015-02-01

    Full Text Available Orientation: Customer relationship management (CRM is important to organisations striving for competitive advantage through building relationships with their customers.Research purpose: This study identified the factors preceding CRM and assessed selected South African small- and medium-sized tourism enterprises’ (SMTEs readiness for CRM.Motivation: CRM is likely to enhance SMTEs’ competitiveness. However, successful adoption and implementation of CRM is unlikely unless the organisation is ready for it.Research design, approach and method: A quantitative research approach and survey questionnaire yielded primary data from 332 respondent organisations selected by systematic sampling. Exploratory factor analysis was used to identify the latent factors preceding CRM readiness. Organisational CRM readiness was assessed based on CRM maturity in terms of data collection, use and sharing throughout the organisation.Main findings: Respondent-organisations performed well on the four factors preceding CRM readiness − business strategy, customer strategy, touch points and competencies, skills and technology and also on data collections and use, but not on data sharing.Practical/Managerial implications: CRM practice is believed to assist organisations in tailoring products and services to customers’ needs, providing customer satisfaction, enhancing customer retention and ultimately improving the organisation’s competitiveness and profitability. CRM might fail if SMTEs do not have CRM-enabling conditions in place and a CRM readiness audit should therefore be performed.Contribution: The study contributes to a largely under-researched area concerning CRM in SMTEs by providing an improved understanding of the factors that will enable SMTEs to engage in CRM activities.

  4. Small grain size zirconium-based coatings deposited by magnetron sputtering at low temperatures

    Energy Technology Data Exchange (ETDEWEB)

    Jimenez, O., E-mail: omar.jimenez.udg@gmail.com [Departamento de Ingeniería de Proyectos, CUCEI, Universidad de Guadalajara, AP 307, CP 45101 Zapopan, Jal (Mexico); Department of Materials Science and Engineering, The University of Sheffield, Sheffield S1 3JD (United Kingdom); Audronis, M.; Leyland, A. [Department of Materials Science and Engineering, The University of Sheffield, Sheffield S1 3JD (United Kingdom); Flores, M.; Rodriguez, E. [Departamento de Ingeniería de Proyectos, CUCEI, Universidad de Guadalajara, AP 307, CP 45101 Zapopan, Jal (Mexico); Kanakis, K.; Matthews, A. [Department of Materials Science and Engineering, The University of Sheffield, Sheffield S1 3JD (United Kingdom)

    2015-09-30

    Hard, partly amorphous, ZrTiB(N) coatings were deposited by Physical Vapour Deposition (PVD) onto (111) silicon wafers at low substrate temperatures of 85 and 110 °C using Closed Field Unbalanced Magnetron Sputtering. A segmented rectangular sputter target composed of three pieces (Zr/TiB{sub 2}/Zr) was used as the source of evaporation of coating components. Two different substrate biases (i.e. floating potential and − 50 V) and N{sub 2} reactive-gas flow rates of 2, 4 and 6 sccm were employed as the main deposition parameter variables. The chemical composition, structure, morphology and mechanical properties were investigated using a variety of analytical techniques such as Glow-Discharge Optical Emission Spectroscopy, cross-sectional Scanning Electron Microscopy (SEM), Glancing Angle X-ray Diffraction (GAXRD) and nanoindentation. With other parameters fixed, coating properties were found to be dependent on the substrate negative bias and nitrogen flow rate. Linear scan profiles and SEM imaging revealed that all coatings were smooth, dense and featureless (in fracture cross section) with no apparent columnar morphology or macro-defects. GAXRD structural analysis revealed that mostly metallic phases were formed for coatings containing no nitrogen, whereas a solid solution (Zr,Ti)N single phase nitride was found in most of the reactively deposited coatings — exhibiting a very small grain size due to nitrogen and boron grain refinement effects. Hardness values from as low as 8.6 GPa up to a maximum of 25.9 GPa are related mainly to solid solution strengthening effects. The measured elastic moduli correlated with the trends in hardness behaviour; values in the range of 120–200 GPa were observed depending on the selected deposition parameters. Also, high H/E values (> 0.1) were achieved with several of the coatings.

  5. PicoBots -A small-sized exploration rover standard for universities

    Science.gov (United States)

    Weiß, André

    This paper will introduce a pico-class robotic platform primarily intended for future lunar exploration. Inspired by the Cubesat standard, an affordable and easy to fabricate design will be introduced allowing universities to develop and perform own rover-based missions. As all major space agencies have set the goal to go to Earths natural satellite in the near future, several opportunities will arise to piggyback to the moon. With a maximum weight of 1 kg, one or multiple PicoBots, plus an eventually needed base station, could easily fill mass budget margins. By utilizing the alternating tripod gait, adapted from simple insects like the cockroach, locomotion can be realized with only two actuators. In comparison to most exploration rovers, the chosen propulsion system leads to a lower number in `degrees of freedom' and therefore a much higher demand for a simple environment. Main advantage, on the other hand, is that it minimizes the complexity of the control-algorithm and reduces the mass as well as the cost. Thanks to the progress in the field of MEMS-based technologies, subsystem components and instruments are available in small sizes, are lightweight and with low power requirements. PicoBots could either be specifically designed for a single mechanical task, e.g. sampling and analysis of rocks, or numerous sensoric payloads, like the seismo-or gravimeter. Swarm intelligence and behavior could also be an interesting field of research. To protect the electronics from radiation, a complementary, multi-layered `spacesuit' will be offered. If needed the suit can also be pressurized thus allowing the use of components not functioning in the vacuum environment.

  6. Job Stress in the United Kingdom: Are Small and Medium-Sized Enterprises and Large Enterprises Different?

    Science.gov (United States)

    Lai, Yanqing; Saridakis, George; Blackburn, Robert

    2015-08-01

    This paper examines the relationships between firm size and employees' experience of work stress. We used a matched employer-employee dataset (Workplace Employment Relations Survey 2011) that comprises of 7182 employees from 1210 private organizations in the United Kingdom. Initially, we find that employees in small and medium-sized enterprises experience lower level of overall job stress than those in large enterprises, although the effect disappears when we control for individual and organizational characteristics in the model. We also find that quantitative work overload, job insecurity and poor promotion opportunities, good work relationships and poor communication are strongly associated with job stress in the small and medium-sized enterprises, whereas qualitative work overload, poor job autonomy and employee engagements are more related with larger enterprises. Hence, our estimates show that the association and magnitude of estimated effects differ significantly by enterprise size. Copyright © 2013 John Wiley & Sons, Ltd.

  7. Effects of Strain Energy and Grain Size on Corrosion Resistance of Ultrafine Grained Fe-20%Cr Steels with Extremely low C and N Fabricated by ECAP

    Directory of Open Access Journals (Sweden)

    Muhammad Rifai

    2015-01-01

    Full Text Available Effect of strain energy and grain size on corrosion resistance of ultrafine grained (UFG Fe-20%Cr steels with extremely low C and N fabricated by equal channel angular pressing (ECAP was investigated. UFG structures of initial grain size of 144 nm exhibited the typical three-stage softening comprising recovery, recrystallization, and grain growth. Potentiodynamic polarization measurements were carried out with a conventional three-electrode cell to evaluate pitting potential. Pitting potential in 1000 mol·m−3 NaCl solution was nobler in UFG state, but pitting potential started to decrease monotonously at lower temperature compared to hardness. The degradation of corrosion resistance in the early stage of annealing is attributed to stability change of passivation by recovery of dislocation structures inside grains and in nonequilibrium grain boundaries. We therefore conclude that nobler potentials of UFG states were realized by not only grain size reduction but also defective deformation-induced UFG.

  8. Market size structure and small business lending : Are crisis times different from normal times?

    NARCIS (Netherlands)

    Berger, Allen N.; Cerqueiro, G.M.; Penas, Maria

    2015-01-01

    Conventional wisdom holds that small banks have comparative advantages vis-à-vis large banks in serving small firms, while recent literature suggests this may not be the case. Using a panel of recent US start-ups, we investigate how small bank presence affects these firms in normal times (2004–06) a

  9. 78 FR 30384 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2013-05-22

    ..., and ranges. SUMMARY: The U.S. Small Business Administration (SBA) is considering granting a class...). According to the waiver request, no small business manufacturers supply this class of products to the... considered available to participate in the Federal market for a class of products, a small...

  10. 76 FR 23640 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2011-04-27

    .... Small Business Administration (SBA) is considering granting a class waiver of the Nonmanufacturer Rule... Manufacturing). According to the request, no small business manufacturers supply this class of products to the... considered available to participate in the Federal market for a class of products, a small...

  11. 75 FR 1662 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-01-12

    ... Classification (NAICS) code 325120. According to a request, no small business manufacturers supply this class of... considered available to participate in the Federal market for a class of products, a small business... From the Federal Register Online via the Government Publishing Office ] SMALL...

  12. 75 FR 32231 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-06-07

    ... equipment. SUMMARY: The U.S. Small Business Administration (SBA) is considering granting a class waiver of... class of products, a small business manufacturer must have submitted a proposal for a contract... From the Federal Register Online via the Government Publishing Office SMALL...

  13. 75 FR 52790 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-08-27

    ... Intensifier Tubes. SUMMARY: The U.S. Small Business Administration (SBA) is considering granting a class... considered available to participate in the Federal market for a class of products, a small business... From the Federal Register Online via the Government Publishing Office SMALL...

  14. 75 FR 13802 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-03-23

    ...: The U.S. Small Business Administration (SBA) is considering granting a class waiver of the... Manufacturing). According to the request, no small business manufacturers supply these class of products to the... From the Federal Register Online via the Government Publishing Office SMALL...

  15. 75 FR 42173 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-07-20

    ... Equipment. SUMMARY: The U.S. Small Business Administration (SBA) is granting a class waiver of the... considered available to participate in the Federal market for a class of products, a small business... From the Federal Register Online via the Government Publishing Office SMALL...

  16. 75 FR 52789 - Small Business Size Standards: Waiver of the Nonmanufacturer Rule

    Science.gov (United States)

    2010-08-27

    ... and Mitten Manufacturing). According to the request, no small business manufacturers supply this class... Nonmanufacturer Rule for any ``class of products'' for which there are no small business manufacturers or... in the Federal market for a class of products, a small business manufacturer must have submitted...

  17. Methotrexate and etanercept-induced primary cutaneous CD4 positive small/medium-sized pleomorphic T-cell lymphoma*

    Science.gov (United States)

    MA, Han; Qiu, Shu; Lu, Rongbiao; Feng, Peiying; Lu, Chun

    2016-01-01

    Immunosuppressive drugs and biological agents may represent a potential risk of lymphoma development in patients with rheumatoid arthritis. But most cases are diffuse, large B-cell lymphomas. Primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma, a provisional entity in the 2005 WHO-EORTC classification of cutaneous lymphomas, is only described in a limited number of reports. To our knowledge, our case is a rare instance of primary cutaneous CD4+ small/medium-sized pleomorphic T-cell lymphoma, after associated treatment with methotrexate and etanercept, in a patient with moderate rheumatoid arthritis who had undergone an orchidectomy incorrectly. PMID:27438209

  18. Simulation and optimization of pyramidal AlGaAs probe with ultra-small spot size and high throughput

    Institute of Scientific and Technical Information of China (English)

    王晓秋; 吴世法; 简国树; 潘石

    2005-01-01

    In this paper, the light-emitting spot sizes and throughputs of the four types of probes are studied using the finitedifference time-domain method, and these probes are also compared in performance. Among these probes, a pyramidal AlGaAs tip coated entirely with a thin Ag film can provide the highest throughput and a single near-field spot size.Probe coated with a 3nm Ag film and incident light with a wavelength of 800nm seems to offer the optimum condition for high throughput and ultra-small spot size, which enables the realization of ultra-high density storage.

  19. Environmental significance of foraminiferal assemblages dominated by small-sized Ammodiscus and Trochammina in Triassic and Jurassic delta-influenced deposits

    Science.gov (United States)

    Nagy, Jenö; Hess, Silvia; Alve, Elisabeth

    2010-04-01

    The sediment packages analyzed for benthic foraminifera consist of mudstones with interbedded sandstones deposited in shallow delta-influenced shelf to deltaic environments. The sections are located in Spitsbergen, the Barents Sea, northern North Sea and Yorkshire, and range in age from Late Triassic to Middle Jurassic. Salient features of the foraminiferal successions are: (1) The assemblages consist entirely or dominantly of agglutinated taxa. (2) The faunal diversities are extremely low. (3) The dominant genera are Ammodiscus and Trochammina. (4) The species are generally of small size compared to usual dimensions within the genera. The features listed above suggest that the assemblages were adapted to restricted conditions (clearly divergent from those of a normal marine shelf), where the main limiting factors were low salinity and reduced amount of dissolved oxygen in unstable, storm-influenced environments. Evidence for environmental conditions is obtained from modern analogues, although the large evolutionary changes in foraminifera during post-Jurassic time make it difficult to find such analogues. Additional information is derived from functional morphology, sedimentary features and paleogeography. The analyzed sediment packages show close faunal similarities suggesting opening of a marine pathway, which connected the paleo-Arctic Ocean with the western European shelf seas in Early Jurassic. A depositional biofacies model of the small-sized Ammodiscus- Trochammina assemblages envisages a delta-influenced shelf environment, where high freshwater influx would have created a density-stratified water column with a tendency to develop hypoxic conditions in its deeper parts. The depth interval between fair-weather and storm wave base (the offshore-transition zone) is indicated as the habitat of the small-sized Ammodiscus- Trochammina assemblages. In this zone, benthic biota would have been stressed by intermittent periods with moderate hypoxia combined with

  20. Dolphin social intelligence: complex alliance relationships in bottlenose dolphins and a consideration of selective environments for extreme brain size evolution in mammals.

    Science.gov (United States)

    Connor, Richard C

    2007-04-29

    Bottlenose dolphins in Shark Bay, Australia, live in a large, unbounded society with a fission-fusion grouping pattern. Potential cognitive demands include the need to develop social strategies involving the recognition of a large number of individuals and their relationships with others. Patterns of alliance affiliation among males may be more complex than are currently known for any non-human, with individuals participating in 2-3 levels of shifting alliances. Males mediate alliance relationships with gentle contact behaviours such as petting, but synchrony also plays an important role in affiliative interactions. In general, selection for social intelligence in the context of shifting alliances will depend on the extent to which there are strategic options and risk. Extreme brain size evolution may have occurred more than once in the toothed whales, reaching peaks in the dolphin family and the sperm whale. All three 'peaks' of large brain size evolution in mammals (odontocetes, humans and elephants) shared a common selective environment: extreme mutual dependence based on external threats from predators or conspecific groups. In this context, social competition, and consequently selection for greater cognitive abilities and large brain size, was intense.

  1. K2-66b and K2-106b: Two Extremely Hot Sub-Neptune-size Planets with High Densities

    Science.gov (United States)

    Sinukoff, Evan; Howard, Andrew W.; Petigura, Erik A.; Fulton, Benjamin J.; Crossfield, Ian J. M.; Isaacson, Howard; Gonzales, Erica; Crepp, Justin R.; Brewer, John M.; Hirsch, Lea; Weiss, Lauren M.; Ciardi, David R.; Schlieder, Joshua E.; Benneke, Bjoern; Christiansen, Jessie L.; Dressing, Courtney D.; Hansen, Brad M. S.; Knutson, Heather A.; Kosiarek, Molly; Livingston, John H.; Greene, Thomas P.; Rogers, Leslie A.; Lépine, Sébastien

    2017-06-01

    We report precise mass and density measurements of two extremely hot sub-Neptune-size planets from the K2 mission using radial velocities, K2 photometry, and adaptive optics imaging. K2-66 harbors a close-in sub-Neptune-sized ({2.49}-0.24+0.34 {R}\\oplus ) planet (K2-66b) with a mass of 21.3+/- 3.6 {M}\\oplus . Because the star is evolving up the subgiant branch, K2-66b receives a high level of irradiation, roughly twice the main-sequence value. K2-66b may reside within the so-called “photoevaporation desert,” a domain of planet size and incident flux that is almost completely devoid of planets. Its mass and radius imply that K2-66b has, at most, a meager envelope fraction (radiation environments. Their high densities reflect the challenge of retaining a substantial gas envelope in such extreme environments.

  2. Effects of a novel forced intensive strengthening technique on muscle size and upper extremity function in a patient with chronic stroke.

    Science.gov (United States)

    Jeong, Hee-Won; Chon, Seung-Chul

    2015-11-01

    [Purpose] This research demonstrated a forced intensive strength technique as a novel treatment for muscle power and function in the affected upper extremity muscle to determine the clinical feasibility with respect to upper extremity performance in a stroke hemiparesis. [Subject and Methods] The subject was a patient with chronic stroke who was dependent on others for performing the functional activities of his affected upper extremity. The technique incorporates a comprehensive approach of forced, intensive, and strength-inducing activities to enhance morphological changes associated with motor learning of the upper extremity. The forced intensive strength technique consisted of a 6-week course of sessions lasting 60 minutes per day, five times a week. [Results] After the 6-week intervention, the difference between relaxation and contraction of the affected extensor carpi radialis muscle increased from 0.28 to 0.63 cm(2), and that of the affected triceps brachii muscle increased from 0.30 to 0.90 cm(2). The results of clinical tests including the modified Ashworth scale (MAS; from 1+ to 1), muscle strength (from 15 to 32 kg), the manual function test (MFT; scores of 16/32 to 27/32 score), the Fugl-Meyer assessment (FMA; scores of 29/66 to 49/66 score), and the Jebsen-Taylor hand function test (JTHFT; from 38/60 to 19/60 sec) were improved. [Conclusion] Our results suggest that the forced intensive strength technique may have a beneficial effect on the muscle size of the upper extremity and motor function in patients with chronic stroke.

  3. Prey size spectra and prey availability of larval and small juvenile cod

    DEFF Research Database (Denmark)

    Munk, Peter

    1997-01-01

    stage when viewed on a relative predator/prey size scale. The study is based on stomach analysis of larval/juvenile cod in the size range 10-35 mm from nursery grounds in the North Sea. Stomach contents (species, size) were compared to environmental composition and preference indices were calculated...... prey biomass was highest in the areas of a hydrographic front, where larvae have been shown to concentrate. Changes in prey availability with larval growth depend strongly on specific prey biomass spectra at a given location. Both increasing and decreasing prey availability al increasing larval size...

  4. Extreme sexual brain size dimorphism in sticklebacks: a consequence of the cognitive challenges of sex and parenting?

    Directory of Open Access Journals (Sweden)

    Alexander Kotrschal

    Full Text Available Selection pressures that act differently on males and females produce numerous differences between the sexes in morphology and behaviour. However, apart from the controversial report that males have slightly heavier brains than females in humans, evidence for substantial sexual dimorphism in brain size is scarce. This apparent sexual uniformity is surprising given that sexually distinct selection pressures are ubiquitous and that brains are one of the most plastic vertebrate organs. Here we demonstrate the highest level of sexual brain size dimorphism ever reported in any vertebrate: male three-spined stickleback of two morphs in an Icelandic lake have 23% heavier brains than females. We suggest that this dramatic sexual size dimorphism is generated by the many cognitively demanding challenges that males are faced in this species, such as an elaborate courtship display, the construction of an ornate nest and a male-only parental care system. However, we consider also alternative explanations for smaller brains in females, such as life-history trade-offs. Our demonstration of unprecedented levels of sexual dimorphism in brain size in the three-spined stickleback implies that behavioural and life-history differences among the sexes can have strong effects also on neural development and proposes new fields of research for understanding brain evolution.

  5. NEW APPROACHES TO CUSTOMER BASE SEGMENTATION FOR SMALL AND MEDIUM-SIZED ENTERPRISES

    Directory of Open Access Journals (Sweden)

    Meleancă Raluca-Cristina

    2012-12-01

    Full Text Available The primary purpose of this paper is to explore current praxis and theory related to customer segmentation and to offer an approach which is best suited for small and medium sized enterprises. The proposed solution is the result of an exploratory research aiming to recognize the main variables which influence the practice of segmenting the customer base and to study the most applied alternatives available for all types of enterprises. The research has been performed by studying a large set of secondary data, scientific literature and case studies regarding smaller companies from the European Union. The result of the research consists in an original approach to customer base segmentation, which combines aspects belonging to different well spread practices and applies them to the specific needs of a small or medium company, which typically has limited marketing resources in general and targeted marketing resources in particular. The significance of the proposed customer base segmentation approach lies in the fact that, even though smaller enterprises are in most economies the greatest in number compared to large companies, most of the literature on targeting practices has focused primarily on big companies dealing with a very large clientele, while the case of the smaller companies has been to some extent unfairly neglected. Targeted marketing is becoming more and more important for all types of companies nowadays, as a result of technology advances which make targeted communication easier and less expensive than in the past and also due to the fact that broad-based media have decreased their impact over the years. For a very large proportion of smaller companies, directing their marketing budgets towards targeted campaigns is a clever initiative, as broad based approaches are in many cases less effective and much more expensive. Targeted marketing stratagems are generally related to high tech domains such as artificial intelligence, data mining

  6. The Small- and Medium-sized Enterprises Office (SME Office) at the European Medicines Agency.

    Science.gov (United States)

    Carr, M

    2010-01-01

    On 15 December 2005, the European Medicines Agency (EMEA) launched an "SME Office" to provide financial and administrative assistance to micro-, small- and medium-sized enterprises (SMEs), with the aim of promoting innovation and the development of new human and veterinary medicinal products by SMEs. According to current EU definition of an SME, companies with fewer than 250 employees, and an annual turnover of not more than 50 million euro or an annual balance sheet total of not more than 43 million euro, are eligible for assistance from the SME Office. Incentives available from the EMEA for SMEs, include: Administrative and procedural assistance from SME Office within the Agency; Fee reductions (90%) for scientific advice and inspections; Fee exemptions for certain administrative services (excluding parallel distribution); Deferral of the fee payable for an application for marketing authorisation or related inspection until after the grant of the marketing authorisation; Conditional fee exemption where scientific advice followed and marketing application is unsuccessful; Assistance with translations of the product information documents. At the end of May 2009, more than 380 companies from 21 countries across the European Economic Area (EEA) had SME status assigned by the EMEA. The large majority of companies are developing medicinal products for human use, 16 are veterinary companies, 15 companies are developing products for both human and veterinary use and 38 are regulatory consultants. Since the SME initiative started the Agency has processed more than 130 requests for scientific advice with fee reductions totalling of 6.9 million euro. Regulatory assistance has been provided to more than 170 companies and 12 companies have benefited from the SME translation service. Stakeholders have acknowledged the significant role the SME Office now plays as a service provider. In the period between January 2006 and June 2009, 34 applications for marketing authorization

  7. Method of evaluating the success of the small and medium-sized enterprises

    Directory of Open Access Journals (Sweden)

    Aleš Peprný

    2010-01-01

    Full Text Available At the time of increasing globalization and homogenization of the global markets, the development of information infrastructure technology and world market becomes accessible not only to large multinational companies but also for small and medium-sized enterprises (SMEs. This has resulted in increasing competition in the domestic market which domestic firms have to face. Therefore the pro­cess of internationalization of business is a step that allows businesses performing their activities in the domestic market to enter foreign markets and to exploit the opportunities and potential which these markets offer. The paper is focused on the draft of the method for quantification of the factors, which determine the success of the SMEs in foreign markets. In the proposed method the multidimensional assessment of indicators of success of SMEs in foreign markets are used, ie. not only the proportion of sales from exports is observed, but also the profitability of international activities in an absolute and in a relative rate. Other indicators of success are the satisfaction of the company management with international activities and the success of achieving defined targets for business activities in foreign markets. Evaluation is made up of both the objective and the subjective indicators of success. Among the objective indicators of success is included the intensity of international activities of SMEs, which is detected as the sum of revenues generated from international activities in relation to total sales company, the profitability of international activities, (ie. whether the foreign activities are profitable or not, and the relative profitability of international activities, where it is ascertained whether the foreign activities generate higher profit than the activities at the domestic market. The next subjective indicator of success is the success of objectives - it was found how many objectives related to operations in foreign markets has been

  8. Improving HVAC operational efficiency in small-and medium-size commercial buildings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woohyun; Katipamula, Srinivas; Lutes, Robert

    2017-08-01

    Small- and medium-size (<100,000 sf) commercial buildings (SMBs) represent over 95% of the U.S. commercial building stock and consume over 60% of total site energy consumption. Many of these buildings use rudimentary controls that are mostly manual, with limited scheduling capability, no monitoring, or failure management. Therefore, many of these buildings are operated inefficiently and consume excess energy. SMBs typically use packaged rooftop units (RTUs) that are controlled by an individual thermostat. There is increased urgency to improve the operating efficiency of existing commercial building stock in the United States for many reasons, chief among them being to mitigate the climate change impacts. Studies have shown that managing set points and schedules of the RTUs will result in up to 20% energy and cost savings. Another problem associated with RTUs is short cycling, when an RTU goes through ON and OFF cycles too frequently. Excessive cycling can lead to excessive wear and to premature failure of the compressor or its components. Also, short cycling can result in a significantly decreased average efficiency (up to 10%), even if there are no physical failures in the equipment. Ensuring correct use of the zone set points and eliminating frequent cycling of RTUs thereby leading to persistent building operations can significantly increase the operational efficiency of the SMBs. A growing trend is to use low-cost control infrastructure that can enable scalable and cost-effective intelligent building operations. The work reported in this paper describes two algorithms for detecting the zone set point temperature and RTU cycling rate that can be deployed on the low-cost infrastructure. These algorithms only require the zone temperature data for detection. The algorithms have been tested and validated using field data from a number of RTUs from six buildings in different climate locations. Overall, the algorithms were successful in detecting the set points and ON

  9. Tacrolimus dosage requirements in living donor liver transplant recipients with small-for-size grafts

    Institute of Scientific and Technical Information of China (English)

    Fei Liu; Ya Li; Xiang Lan; Yong-Gang Wei; Bo Li; Lv-Nan Yan; Tian-Fu Wen; Ji-Chun Zhao; Ming-Qing Xu; Wen-Tao Wang; Jia-Yin Yang

    2009-01-01

    AIM: To investigate the tacrolimus dosage requirements and blood concentrations in adult-to-adult right lobe living donor liver transplantation (AALDLT) recipients with small-for-size (SFS) grafts.METHODS: During January 2007 and October 2008, a total of 54 cases of AALDLT with an observation period of 6 mo were enrolled in this study. The 54 patients were divided into two groups according to graftrecipient body weight ratio (GRBW): SFS grafts group (Group S, GRBW < 0.8%, n = 8) and non-SFS grafts group (Group N, GRBW ≥ 0.8%, n = 46). Tacrolimus 12-hour blood levels and doses were recorded during weeks 1, 2, 3 and 4 and months 2, 3, 4, 5 and 6 in group S and group N. Meanwhile, acute rejection rates,liver and renal function test results, and the number of potentially interacting medications were determined at each interval in the two groups. A comparison of tacrolimus dosage requirements and blood levels were made weekly in the first month post-surgery, and monthly from months 2 to 6.RESULTS: There were no differences in the demographic Demographic characteristics, acute rejection rates, liver and renal function test results, or the number of potentially interacting medications administered between the two groups. The tacrolimus dosage requirements in group S were significantly lower than group N at 2 wk (2.8 ± 0.4 mg/d vs 3.6 ± 0.7 mg/d, P = 0.006), 3 wk (2.9 ± 0.7 mg/d vs 3.9 ± 0.8 mg/d, P = 0.008), 4 wk (2.9 ± 0.8 mg/d vs 3.9 ± 1.0 mg/d, P = 0.023) and 2 mo (2.8 ± 0.7 mg/d vs 3.8 ± 1.1 mg/d, P = 0.033). Tacrolimus 12-h trough concentrations were similar between the two groups at all times except for 2 wk post-transplantation,when the concentrations were significantly greater in group S recipients than in group N recipients (11.3 ± 4.8 ng/mL vs 7.0 ± 3.8 ng/mL, P = 0.026).CONCLUSION: SFS grafts recipients have significantly decreased tacrolimus dosage requirements compared with non-SFS grafts recipients in AALDLT during the first 2 mo post-surgery.

  10. Knowledge Management Acceptance: Success Factors amongst Small and Medium-Size Enterprises

    Directory of Open Access Journals (Sweden)

    Christine N.L.  TAN

    2011-01-01

    Full Text Available Problem statement: The value and importance of knowledge, as seen by numerous organisations today, does without a doubt play a crucial role in the current ever-challenging and aggressive business environment. As a result, businesses that aspire to be labelled as being successful and competitive need to seek and find better ways to improve their firms’ performance. Hence, Knowledge Management (KM, which is viewed as a source of sustainable competitive advantage, has attracted the attention of various companies all over the business world, including Small and Medium-Size Enterprises (SMEs in Malaysia. With the realisation of KM, the systematic management of organisation knowledge - a strategic corporate asset not to be taken lightly; can thus be created, transferred, shared and, utilised, in pushing for greater organisational competitiveness, innovativeness and, productivity. This research examined the success factors that help to increase the business performance of SMEs in Malaysia. Besides, it also highlighted the importance and contribution of KM amongst SMEs. Therefore, the reason behind this study is to understand and recognised the acceptance of KM and therefore further classified the success factors that contributed to the business performance outcome amongst SMEs in Malaysia. With this, the success factors observed in this research; culture; leadership; employee participation; Information and Communications Technology (ICT; organisational structure; are thoroughly investigated to explore on whether these factors have an impact on knowledge creation; knowledge transfer; knowledge sharing and knowledge utilisation; of KM processes among SMEs in Malaysia. Approach: This study aids to determined and examined the success factors; culture; leadership; employee participation; Information and Communications Technology (ICT; organisational structure; of SMEs that further influences KM processes; knowledge creation, transfer, sharing, utilisation

  11. Comparison of Turbulence Models in Simulation of Flow in Small-Size Centrifugal Compressor

    Directory of Open Access Journals (Sweden)

    B. B. Novickii

    2015-01-01

    Full Text Available The aim of the work is the choice of turbulence model for the closure of the Reynoldsaveraged Navier-Stokes equations for calculation of the characteristics of small-size centrifugal compressor. To this were built three-dimensional sectors (as the compressor axisymmetric blade impeller and the diffuser of the centrifugal compressor on the basis of which they were created two grid models. The dimension of the grid model for the calculation models of turbulence komega and SST was 1.4 million. Elements and the dimensionless parameter y + does not exceed 2. turbulence model family k-epsilon model grid was also 1.4 million. Elements, and the dimensionless parameter y + was greater than 20, which corresponds to recommended values. The next part of the work was the task of boundary conditions required for the correct ca lculation. When the impeller inlet pawned pressure working fluid and the total temperature at the outlet and the gas flow rate through the stage. On the side faces sectors pawned boundary cond ition «Periodic», allowing everything except the wheel, but only axisymmetric part, which significantly reduces the required computational time and resources. Accounting clearance in addition to the meridional geometry construction additionally taken into account boundary condition «Counter Rotating Wall», which allows you to leave the domain in the rotating disc fixed coa ting.The next step was to analyze the results of these calculations, which showed that the turbulence model k-epsilon and RNG does not show the velocity vectors in the boundary layer, and "pushes" the flow from the blade using wall functions. At the core of the flow turbulence model k-omega shown for the undisturbed flow, which is not typical for the compressor working on predpompazhnom mode. For viscous gas diffuser vane for turbulence models SST, k-omega, RNG k-epsilon and has a similar character.The paper compares the characteristics of pressure centrifugal compressor

  12. Perceived impediments to export involvement among small and medium sized firms : non-exporters perspective

    Directory of Open Access Journals (Sweden)

    Mercy Mpinganjira

    2011-12-01

    Full Text Available Purpose: The main purpose of this paper is to examine perceived impediments to export involvement among non-exporting small and medium sized firms (SME's in Malawi. The study also examines levels of interest in exporting among the firms. Problem investigated: Many countries have programs aimed at promoting export involvement among SME's. Despite this, most SME's continue to ignore exporting as a viable business strategy. Information on perceived impediments to export involvement especially from the non-exporters' perspective is often lacking hence the need for this study. Methodology: Data was collected from 80 owner managers of non-exporting SME's. A structured questionnaire was the main instrument used to collect data. Personal interviews were also held with managers for the purposes of probing their answers to the questions in the questionnaire. Statistical Package for Social Science (SPSS version 18 was used to analyse the quantitative data obtained from use of the structured questionnaire. Qualitative data obtained through personal interviews was analysed used thematic analysis. Findings: The findings of the study showed significant levels of interest in exporting among the firms. The majority of the owner managers indicated willingness to exploit export opportunities that may be readily available to them. The findings however showed that just over half of the respondents had discussed or investigated the possibility of exporting before. On impediments to exporting, the findings showed that managers perceive many factors as important impediments to their firm's involvement in exporting. The top two most important impediments were internal to the firm and related to human resource issues. They included insufficient knowledge about export opportunities and lack of personnel knowledgeable in exporting. Originality and value of the research: A review of literature shows that most export promotion studies tend to focus more on issues relating to

  13. Empirical development taxanomy of micro, small and medium-sized enterprises in South Moravian Region

    Directory of Open Access Journals (Sweden)

    Veronika Bumberová

    2013-01-01

    Full Text Available This paper represents a pilot study examining entrepreneurial behavior patterns within the area of development of micro, small and medium-sized market active enterprises in South Moravian Region from the perspective of strategic management. The main aim of this article is to classify the enterprises by the character of development activities into relatively homogeneous groups and identify those activities that contribute to considerable differences between the individual groups. Empirical evidence is based on a quantitative survey in terms of a random choice of respondents obtained by means of an e-mail questionnaire. The major analytic procedure applied within this research comprises methods of Cluster Analysis and validation technique based on chi-square and G-square nonparametric tests for testing differences (independence of variables between the clusters. By means of Cluster Analysis three relatively homogenous SME groups were identified. The first cluster, called “global”, (approximately 6% of the respondents prevails in most of the strategic development aspects of the researched enterprises. Global SMEs rely on development activities in the area of product innovations and risk diversification into other activities. In terms of changes in functional strategies this involves primarily the area of new technology and human resources development, and the ability to benefit from participation in networks of cooperating organizations. The second cluster, called “transition”, (approximately 59% of the respondents is developed mainly by means of investments in business specific knowledge, and/or in technical skills of their employees. They are more conservative in the area of product innovations and risk diversification into other activities, which is then reflected in a lower level of investments in technologies and marketing. In comparison with global enterprises the major difference lies in a much lower number of activities in the area

  14. Development and Evaluation of Algorithms to Improve Small- and Medium-Size Commercial Building Operations

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Woohyun [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Katipamula, Srinivas [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Lutes, Robert G. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States); Underhill, Ronald M. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States)

    2016-10-31

    Small- and medium-sized (<100,000 sf) commercial buildings (SMBs) represent over 95% of the U.S. commercial building stock and consume over 60% of total site energy consumption. Many of these buildings use rudimentary controls that are mostly manual, with limited scheduling capability, no monitoring or failure management. Therefore, many of these buildings are operated inefficiently and consume excess energy. SMBs typically utilize packaged rooftop units (RTUs) that are controlled by an individual thermostat. There is increased urgency to improve the operating efficiency of existing commercial building stock in the U.S. for many reasons, chief among them is to mitigate the climate change impacts. Studies have shown that managing set points and schedules of the RTUs will result in up to 20% energy and cost savings. Another problem associated with RTUs is short-cycling, where an RTU goes through ON and OFF cycles too frequently. Excessive cycling can lead to excessive wear and lead to premature failure of the compressor or its components. The short cycling can result in a significantly decreased average efficiency (up to 10%), even if there are no physical failures in the equipment. Also, SMBs use a time-of-day scheduling is to start the RTUs before the building will be occupied and shut it off when unoccupied. Ensuring correct use of the zone set points and eliminating frequent cycling of RTUs thereby leading to persistent building operations can significantly increase the operational efficiency of the SMBs. A growing trend is to use low-cost control infrastructure that can enable scalable and cost-effective intelligent building operations. The work reported in this report describes three algorithms for detecting the zone set point temperature, RTU cycling rate and occupancy schedule detection that can be deployed on the low-cost infrastructure. These algorithms only require the zone temperature data for detection. The algorithms have been tested and validated using

  15. Energetic Communities: Planning support for sustainable energy transition in small- and medium-sized communities

    Directory of Open Access Journals (Sweden)

    Christina Valeska Sager-Klauss

    2016-04-01

    Full Text Available The necessity for transition in the energy sector is beyond dispute and high on the political agendas. Climate change, the depletion of fossil fuels and the vulnerability of economies to resource speculation and unreliable political systems in the producing countries lay path for a broad implementation of smart alternative solutions. This means the integration of more sustainable renewable energy sources in the existing supply structures or the displacement of existing systems by new ones. Cities and communities are central players in the energy transition process. Energy demand is determined by the built environment. Renewable energy production needs space. The conflicts between different interest groups often break out in the context of local implementation measures that affect urban planning and the appearance of landscapes.Small- and medium-sized communities might prove to be game-changers in the overall energy transition because many problems have to be solved within their ambit. Urban planning is dealing with the numerous processes of urban change. Energy is a fairly new task to be addressed and many stakeholders lack experience and criteria for strategic decision making. After a period of fierce determination to turn the wheel against climate change, it seems that there is a growing resignation among politicians, planners and the public because some things have not turned out the way we’d expected and the hope for quick solutions fades. Rebound-effects seem to eat up the savings to a good extent, and alternative ideas of how sustainable energy systems may be put into place have not yet been persuasive in many cases. Energy systems have proved to be complex. They are still perceived to be important but in practice there is a growing uneasiness about the right steps to take. The overarching research question of this thesis is: What do decision makers in smalland medium-sized communities need to become more successful in implementing

  16. The -G1245A IGF1 polymorphism is related with small head size and less brain sparing in small for gestational age born children.

    Science.gov (United States)

    Ester, Wietske A; van Meurs, Joyce B; Arends, Nicolette J; Uitterlinden, André G; de Ridder, Maria A; Hokken-Koelega, Anita C

    2009-04-01

    Small for gestational age (SGA) subjects experience pre- and postnatal growth restriction, which might be influenced by polymorphisms in the IGF1 gene. The well-known -841(CA)(n)/192 bp polymorphism has been associated with birth size, cardiovascular disease, and IGF-1 levels, and is in linkage disequilibrium with the -G1245A single nucleotide polymorphism (SNP; rs35767). To associate the -G1245A SNP with head circumference (HC) and brain sparing (a greater head compared with height SDS) in short SGA and SGA catch-up subjects. Gene association study. We studied 635 SGA subjects out of which 439 remained short and 196 had a postnatal height >-2.00 SDS. The -G1245A SNP IGF1 gene polymorphism and head size. All SGA subjects had a postnatal head size below the population mean (-1.01 SDS, P<0.001). Whereas SGA catch-up subjects had a head size that was in proportion with their height, short SGA subjects displayed extensive brain sparing (HC - height: SGA CU: 0.01 versus short SGA: 1.75 SDS, P<0.001). The most severely SGA born subjects had a 0.4 SDS smaller postnatal head size and 0.6 SDS less brain sparing when carrying the -1245 A-allele in contrast to G-allele carriers (P=0.03). The association between the -G1245A SNP and head size remained significant after correction for birth weight and postnatal height SDS (P=0.03). Birth weight, birth length and postnatal height SDS were not related with the - G1245A SNP. The -1245 A-allele of the IGF1 promoter SNP is associated with a small head size and less brain sparing in SGA born subjects and particularly those with the lowest birth weight.

  17. Performance Measurement in Small and Medium-Sized Enterprises - Literature Review and Results from a German Case Study

    DEFF Research Database (Denmark)

    Brem, Alexander; Kreusel, N.; Neusser, N.

    2008-01-01

    A literature review of Performance Measurement Systems (PMS) in Small- and Medium-sized Enterprises (SMEs) shows that the main contributions focus on the development of theoretical models, but not on guidelines for practical implementation. In this context, an important neglected aspect...

  18. Virtual Class: Distance Learning for Small and Medium Sized Enterprises in the Spanish Region of Castilla y Leon.

    Science.gov (United States)

    Rodriguez, Blanca; Perez, Maria Angeles; Verdu, Maria Jesus; Navazo, Maria Agustina; Lopez, Ricardo; Mompo, Rafael; Garcia, Joaquin

    Lifelong learning is becoming a necessity in the new Information Society where everyone, particularly small and medium sized enterprises (SMEs), must keep up with new technologies. Education and training are of the most importance in this updating. An interdisciplinary and inter-university work group called "Canalejas" (Spain) has developed a…

  19. The relationship between employee initiatives and professional expertise throughout the career in small and medium-sized enterprises

    NARCIS (Netherlands)

    van der Heijden, Beatrice

    2002-01-01

    The present study describes the relationship between three individual predictor variables and the degree of occupational expertise of middle and higher-level employees in three different career stages working in small and medium-sized enterprises (SMEs). Occupational expertise is operationalised by

  20. Attitudes about OCLC in Small and Medium-Sized Libraries. Illinois Valley Library System OCLC Experimental Project. Report No. 4.

    Science.gov (United States)

    Bills, Linda G.; Wilford, Valerie

    A project was conducted from 1980 to 1982 to determine the costs and benefits of OCLC use in 29 small and medium-sized member libraries of the Illinois Valley Library System (IVLS). Academic, school, public, and special libraries participated in the project. Based on written attitude surveys of and interviews with library directors, staff,…

  1. Science Parks and the Co-location of High-tech Small- and Medium Sized Firms in China's Shenzhen

    NARCIS (Netherlands)

    Cheng, F.; van Oort, F.G.; Geertman, S.C.M.; Hooimeijer, P.

    2014-01-01

    Science parks (SPs) have received special attention as a policy tool to facilitate localised economic growth by attracting high-tech firms, especially small- and medium-sized enterprises (SMEs). The effectiveness of this strategy has been called into question. Empirical studies suggest that the

  2. Deriving Default Dermal Exposure Values for Use in a Risk Assessment Toolkit for Small and Medium-sized Enterprises

    NARCIS (Netherlands)

    Warren, N.; Goede, H.A.; Tijssen, S.C.H.A.; Oppl, R.; Schipper, H.J.; Hemmen, J.J. van

    2003-01-01

    This paper describes the derivation of default task-based dermal exposure values for use in a risk assessment toolkit for small and medium-sized enterprises (SMEs). A set of separately determined dermal exposure modifiers have been applied to published studies of dermal exposure to obtain 'normalize

  3. Encouraging professional development in small and medium-sized firms. The influence of career history and job content

    NARCIS (Netherlands)

    Heijden, van der Beatrice

    2001-01-01

    The present study describes the relationship between three job-related predictor variables and the degree of professional expertise of middle and higher level employees, working in small and medium-sized firms, in three different career stages. The factors in question are: total number of jobs that

  4. Energy conservation of small and medium-sized businesses in the Netherlands; MKB houdt niet van energiebesparen

    Energy Technology Data Exchange (ETDEWEB)

    Mulder, A. [ed.

    2001-05-17

    According to a report of the Energy research Centre of the Netherlands (ECN) in Petten, Netherlands, knowledge and attitudes of small and medium-sized businesses (SME's) with respect to energy conservation should change. Contrary to what SME-representatives believe there are profitable options for them to save energy, to be stimulated by branch organizations for SME's.

  5. UCD4SME: Small to Medium-sized Enterprises involving their users and clients for product innovation

    NARCIS (Netherlands)

    De Lille, C.S.H.

    2014-01-01

    An increasing number of Small to Medium-sized Enterprises (SMEs) starts to realize the opportunities offered by User-centred Design (UCD). The issue is that our understanding of UCD either comes from large companies or is developed in an academic setting, without taking SMEs into account. This resea

  6. The influence of CEO gender on market orientation and performance in service small and medium-sized service businesses

    NARCIS (Netherlands)

    Davis, Peter S.; Babakus, Emin; Danskin Englis, Paula; Pett, Tim

    2010-01-01

    This study examines the effects of CEO gender on market orientation and performance (growth and profitability) among a sample of small and medium-sized service businesses. Gender was found to have significant indirect effects (via market orientation) on both market performance (growth) and financial

  7. Optimizing the design of small-sized nucleus breeding programs for dairy cattle with minimal performance recording

    NARCIS (Netherlands)

    Kariuki, C.M.; Komen, J.; Kahi, A.K.; Arendonk, van J.A.M.

    2014-01-01

    Dairy cattle breeding programs in developing countries are constrained by minimal and erratic pedigree and performance recording on cows on commercial farms. Small-sized nucleus breeding programs offer a viable alternative. Deterministic simulations using selection index theory were performed to

  8. Encouraging professional development in small and medium-sized firms. The influence of career history and job content

    NARCIS (Netherlands)

    van der Heijden, Beatrice

    2001-01-01

    The present study describes the relationship between three job-related predictor variables and the degree of professional expertise of middle and higher level employees, working in small and medium-sized firms, in three different career stages. The factors in question are: total number of jobs that

  9. A Bayesian Approach to International Distributor Selection for Small and Medium-Sized Enterprises in the Software Industry

    Science.gov (United States)

    Lui, Joseph P.

    2013-01-01

    Identifying appropriate international distributors for small and medium-sized enterprises (SMEs) in the software industry for overseas markets can determine a firm's future endeavors in international expansion. SMEs lack the complex skills in market research and decision analysis to identify suitable partners to engage in global market entry.…

  10. UCD4SME: Small to Medium-sized Enterprises involving their users and clients for product innovation

    NARCIS (Netherlands)

    De Lille, C.S.H.

    2014-01-01

    An increasing number of Small to Medium-sized Enterprises (SMEs) starts to realize the opportunities offered by User-centred Design (UCD). The issue is that our understanding of UCD either comes from large companies or is developed in an academic setting, without taking SMEs into account. This

  11. The Cooperation of Small and Middle-Sized Companies with Universities in Turkey: Acquiring Enterprising Skills Project

    Science.gov (United States)

    Dalyan, Figen

    2004-01-01

    Higher education institutions are the places from where the societies base the information, deliver and apply it. Moreover, it is the place where the people who are required to bring innovations with required abilities, skills and attitudes are trained. Forming a network between the small and middle sized companies (SMSC) and higher education…

  12. Using Computer-Based Continuing Professional Education of Training Staff to Develop Small- and Medium-Sized Enterprises in Thailand

    Science.gov (United States)

    Sooraksa, Nanta

    2012-01-01

    This paper describes a career development program for staff involved in providing training for small- and medium-sized enterprises (SMEs) in Thailand. Most of these staff were professional vocational teachers in schools. The program uses information communication technology (ICT), and its main objective is to teach Moodle software as a tool for…

  13. Entrepreneurial Training for the Growth of Small and Medium-Sized Enterprises: Lessons from Central and Eastern Europe. Report.

    Science.gov (United States)

    European Training Foundation, Turin (Italy).

    This report brings together a number of principles as to best practice in supporting, through training, growth of small and medium-sized enterprises (SMEs) in Central and Eastern Europe. Chapter 2 identifies key principles to be drawn from the West through a literature review. Chapter 3 reviews the "practice" of entrepreneurial training…

  14. Why do people buy dogs with potential welfare problems related to extreme conformation and inherited disease? A representative study of Danish owners of four small dog breeds

    DEFF Research Database (Denmark)

    Sandøe, Peter; Kondrup, Sara Vincentzen; Bennett, P.C.

    2017-01-01

    number of dog breeds suffer from welfare problems due to extreme phenotypes and high levels of inherited diseases but the popularity of such breeds is not declining. Using a survey of owners of two popular breeds with extreme physical features (French Bulldog and Chihuahua), one with a high load...... of inherited diseases not directly related to conformation (Cavalier King Charles Spaniel), and one representing the same size range but without extreme conformation and with the same level of disease as the overall dog population (Cairn Terrier), we investigated this seeming paradox. We examined planning...... and motivational factors behind acquisition of the dogs, and whether levels of experienced health and behavior problems were associated with the quality of the owner-dog relationship and the intention to re-procure a dog of the same breed. Owners of each of the four breeds (750/breed) were randomly drawn from...

  15. Small portion sizes in worksite cafeterias: do they help consumers to reduce their food intake?

    National Research Council Canada - National Science Library

    Vermeer, W M; Steenhuis, I H M; Leeuwis, F H; Heymans, M W; Seidell, J C

    2011-01-01

    ... consumers (that is, health education) or at altering the food environment in such a way that the healthy choice is made more easily available. This could be achieved by for instance offering smaller portion sizes or by keeping the prices per unit stable (that is, proportional pricing). Two studies have shown that decreasing portion sizes can decrease pe...

  16. 78 FR 37397 - Small Business Size Standards: Agriculture, Forestry, Fishing and Hunting

    Science.gov (United States)

    2013-06-20

    ... Investment Company (SBIC), 7(a), and the Certified Development Company (CDC or 504) Loan Programs determine... standards during every 18-month period from the date of its enactment and review all size standards not less... changes to size standards on its loan programs, SBA examined data on its own guaranteed loan programs for...

  17. Multifractal Analysis of the Small Time-Scale Boundary-Layer Characteristics of the Wind: the Anisotropy and Extremes

    Science.gov (United States)

    Fitton, G. F.; Tchiguirinskaia, I.; Schertzer, D. J.; Lovejoy, S.

    2012-12-01

    anisotropic over high frequencies, where u1 most scales as Bolgiano-Obukhov and u2 scales as Kolmogorov. The scaling law of the vertical shears of the horizontal wind in the array varied from Kolmogorov to Bolgiano-Obukhov with height depending on the condition of stability. We interpret the results with the UM anisotropic model that greatly enhances our understanding of the ABL structure. Comparing the two case studies we found in both cases the multifractality parameter of about 1.6, which remains close to the estimates obtained for the free atmosphere. From the UM parameters, the exponent of the power law of the distribution of the extremes can be predicted. Over small scales, this exponent is of about 7.5 for the wind velocity, which is a crucial result for applications within the field of wind energy.

  18. Expression of iNOS in early injury in a rat model of small-for-size liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Wei-Wei Jiang; Lian-Bao Kong; Guo-Qiang Li; Xue-Hao Wang

    2009-01-01

    BACKGROUND: Living donor liver transplantation has been widely accepted as the treatment of choice for end-stage liver disease. Large amounts of nitric oxide generated by inducible nitric oxide synthase (iNOS) have been shown to play an important role in many inlfammatory and immune reactions, but expression of iNOS in small-for-size liver transplantation is unknown. The aims of this study were to determine the time course of iNOS mRNA and protein as well as the redox state of liver biopsies in a rat model of small-for-size liver transplantation. METHODS: Male Sprague-Dawley rats were divided into a control group, a warm ischemia-reperfusion (IR) group, and a small-for-size liver graft group. Real-time RT-PCR and Western blotting were used to characterize the time course of the expression of iNOS mRNA and protein, respectively. Malondialdehyde (MDA) and superoxide dismutase (SOD) were used as markers to characterize the redox state of liver tissues, and the time courses of MDA and SOD levels were also measured. RESULTS: The expression of iNOS mRNA and protein levels in the warm IR and small-for-size graft groups both signiifcantly increased after reperfusion, and peaked at 3 hours. Moreover, the increase in MDA was accompanied by increased iNOS in the period of 1-24 hours after reperfusion. The MDA levels in the warm IR and small-for-size graft groups signiifcantly increased after reperfusion, peaked at 3 hours, and decreased thereafter. The direction of change in SOD was opposite that of the change in MDA.CONCLUSIONS: The expression of iNOS mRNA and protein is activated after reperfusion both in hepatic warm IR injury and small-for-size liver graft. Furthermore, the results of this study suggest that iNOS contributes to the damage in warm IR injury and small-for-size grafts via free oxygen radicals.

  19. One man's tall is another man's small: how the framing of portion size influences food choice.

    Science.gov (United States)

    Just, David R; Wansink, Brian

    2014-07-01

    Labels such as 'Large' or 'Super-size' are often used to describe portion sizes. How do these normative labels influence consumer choice and how much they ultimately either consume or waste? Although one might believe that firms use normative labels to impact choice behavior through loss aversion, a field experiment shows consumer's willingness to pay is inconsistent with a loss aversion explanation. Although portions were clearly visible, individuals appeared to use the labels as objective information about their size. Importantly, a second study showed these labels also led people to eat less when food was given a larger sounding name than a smaller name (double vs. regular; regular vs. half-size). If labels are used as size information, policies governing normative names could help reduce food consumption or reduce waste.

  20. Statistical modelling of wildfire size and intensity: a step toward meteorological forecasting of summer extreme fire risk

    OpenAIRE

    Hernandez, C; Keribin, C.; Drobinski, P.; Turquety, S.

    2015-01-01

    International audience; In this article we investigate the use of statistical methods for wildfire risk assessment in the Mediterranean Basin using three meteorological covariates, the 2 m temperature anomaly, the 10 m wind speed and the January– June rainfall occurrence anomaly. We focus on two remotely sensed characteristic fire variables, the burnt area (BA) and the fire radiative power (FRP), which are good proxies for fire size and intensity respectively. Using the fire data we determine...