WorldWideScience

Sample records for extremely mild conditions

  1. Extreme meteorological conditions

    International Nuclear Information System (INIS)

    Altinger de Schwarzkopf, M.L.

    1983-01-01

    Different meteorological variables which may reach significant extreme values, such as the windspeed and, in particular, its occurrence through tornadoes and hurricanes that necesarily incide and wich must be taken into account at the time of nuclear power plants' installation, are analyzed. For this kind of study, it is necessary to determine the basic phenomenum of design. Two criteria are applied to define the basic values of design for extreme meteorological variables. The first one determines the expected extreme value: it is obtained from analyzing the recurence of the phenomenum in a convened period of time, wich may be generally of 50 years. The second one determines the extreme value of low probability, taking into account the nuclear power plant's operating life -f.ex. 25 years- and considering, during said lapse, the occurrence probabilities of extreme meteorological phenomena. The values may be determined either by the deterministic method, which is based on the acknowledgement of the fundamental physical characteristics of the phenomena or by the probabilistic method, that aims to the analysis of historical statistical data. Brief comments are made on the subject in relation to the Argentine Republic area. (R.J.S.) [es

  2. Hygienic diagnosis in extreme conditions

    International Nuclear Information System (INIS)

    Sofronov, G.A.

    1997-01-01

    Review for book by M.P. Zakharchenko, S.A. Lopatin, G.N. Novozhilov, V.I. Zakharov Hygienic diagnosis in extreme conditions is presented discussing the problem of people health preservation under extreme conditions. Hygienic diagnosis is considered illustrated by cases of hostilities (Afghan War), earthquake response in Armenia (1988) and Chernobyl accident response. Attention is paid to the estimation of radiation doses to people and characteristics of main types of dosimeters. The high scientific level of the book is marked

  3. Extreme Conditions Modeling Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Coe, R. G.; Neary, V. S.; Lawson, M. J.; Yu, Y.; Weber, J.

    2014-07-01

    Sandia National Laboratories (SNL) and the National Renewable Energy Laboratory (NREL) hosted the Wave Energy Converter (WEC) Extreme Conditions Modeling (ECM) Workshop in Albuquerque, NM on May 13th-14th, 2014. The objective of the workshop was to review the current state of knowledge on how to model WECs in extreme conditions (e.g. hurricanes and other large storms) and to suggest how U.S. Department of Energy (DOE) and national laboratory resources could be used to improve ECM methods for the benefit of the wave energy industry.

  4. Extreme conditions (p, T, H)

    Energy Technology Data Exchange (ETDEWEB)

    Mesot, J [Lab. for Neutron Scattering ETH Zurich, Zurich (Switzerland) and Paul Scherrer Institute, Villigen (Switzerland)

    1996-11-01

    The aim of this paper is to summarize the sample environment which will be accessible at the SINQ. In order to illustrate the type of experiments which will be feasible under extreme conditions of temperature, magnetic field and pressure at the SINQ a few selected examples are also given. (author) 7 figs., 14 refs.

  5. Extreme Conditions Modeling Workshop Report

    Energy Technology Data Exchange (ETDEWEB)

    Coe, Ryan Geoffrey [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Neary, Vincent Sinclair [Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States); Lawon, Michael J. [National Renewable Energy Lab. (NREL), Golden, CO (United States); Yu, Yi-Hsiang [National Renewable Energy Lab. (NREL), Golden, CO (United States); Weber, Jochem [National Renewable Energy Lab. (NREL), Golden, CO (United States)

    2014-07-01

    Sandia National Laboratories (SNL) and the National Renewable Energy Laboratory (NREL) hosted the Wave Energy Converter (WEC) Extreme Conditions Modeling (ECM) Workshop in Albuquerque, New Mexico on May 13–14, 2014. The objective of the workshop was to review the current state of knowledge on how to numerically and experimentally model WECs in extreme conditions (e.g. large ocean storms) and to suggest how national laboratory resources could be used to improve ECM methods for the benefit of the wave energy industry. More than 30 U.S. and European WEC experts from industry, academia, and national research institutes attended the workshop, which consisted of presentations from W EC developers, invited keynote presentations from subject matter experts, breakout sessions, and a final plenary session .

  6. Shocking matter to extreme conditions

    International Nuclear Information System (INIS)

    Gupta, Y.M.; Sharma, S.M.

    1997-01-01

    A good understanding of the thermodynamic response of matter at high compression and high energy densities is important to several areas of physics. Shock-wave experiments are uniquely suited for obtaining data at extreme conditions, and a shock-compressed matter can be viewed as a condensed system with or without dissociation or as a strongly coupled plasma. This article reviews work by Da Silva et al. in which irradiances ranging from 5x10 superscript 12 to 2x10 superscript 14 W/cm 2 were used to generate 8- to 10-ns square pulses in liquid deuterium. The authors demonstrated negligible pre-heating of the sample, steady propagation of the shock wave, and direct determination of the shock wave velocity along with particle velocity and density in the shocked state. Da Silva et al. results are compared with models and other experimental information, and the usefulness of the data in other areas is assessed. 11 refs., 1 fig

  7. Heavy fermions and extreme conditions

    International Nuclear Information System (INIS)

    Cheikine, Ilia

    2000-01-01

    Three heavy electron systems, CeCu 2 Si 2 , CePd 2 Si 2 and UGe 2 , were investigated by transport, quantum oscillations (CePd 2 Si 2 ) and neutron diffraction (UGe 2 ) measurements. The experiments were performed under extreme conditions of very low temperature, high magnetic field and hydrostatic pressure. In the case of CeCu 2 Si 2 , we followed the evolution of the magnetic A-phase that is found to collapse rapidly under pressure. We found evidence for a relation between the A-phase and the presence of a maximum in the temperature dependence of H c2 . Our analysis showed that at low pressure, the sign of the exchange integral should be negative, thus superconductivity is enhanced by an increase in the paramagnetic susceptibility as in the Jaccarino-Peter effect. The anisotropy of the initial slope of H c2 and therefore that of the effective mass was found to change under pressure. For CePd 2 Si 2 , both the de Haas-van Alphen effect at ambient pressure and the electrical resistivity under pressure were studied. The latter reveals a non-Fermi liquid behavior in the vicinity of the antiferromagnetic quantum critical point, P c ∼ kbar. The analysis of H c2 at P c shows that the superconducting state is well described by a weak coupling, clean limit model with a slightly anisotropic orbital limit and a strongly anisotropic paramagnetic one. UGe 2 is shown to demonstrate the coexistence of ferromagnetism and superconductivity that develops just below the ferromagnetic quantum critical point, P c ∼16 kbar. The measurements of the resistivity under pressure point to a possible existence of another phase boundary and thus another quantum critical point, P x ∼ 12 kbar, within the ferromagnetic state. The P-T phase diagram containing both P c and P x was sketched, and a possible relation between P x and the development of superconductivity was discussed. The temperature dependence of H c2 demonstrates a variety of novel behaviors, which cannot be understood within

  8. Complex Plasma Research Under Extreme Conditions

    International Nuclear Information System (INIS)

    Ishihara, Osamu

    2008-01-01

    Complex plasma research under extreme conditions is described. The extreme conditions include low-dimensionality for self-organized structures of dust particles, dust magnetization in high magnetic field, criticality in phase transition, and cryogenic environment for Coulomb crystals and dust dynamics.

  9. Injuries in an Extreme Conditioning Program

    OpenAIRE

    Aune, Kyle T.; Powers, Joseph M.

    2016-01-01

    Background: Extreme conditioning programs (ECPs) are fitness training regimens relying on aerobic, plyometric, and resistance training exercises, often with high levels of intensity for a short duration of time. These programs have grown rapidly in popularity in recent years, but science describing the safety profile of these programs is lacking. Hypothesis: The rate of injury in the extreme conditioning program is greater than the injury rate of weightlifting and the majority of injuries occ...

  10. Lower extremity function in normal cognitive aging, mild cognitive impairment, and Alzheimer’s disease

    NARCIS (Netherlands)

    Eggermont, L.H.P.; Gavett, B.E.; Volkers, K.M.; Blankevoort, C.G.; Scherder, E.J.A.; Jefferson, A.L.; Steinberg, E.; Nair, A.; Green, R.C.; Stern, R.A.

    2010-01-01

    Eggermont LH, Gavett BE, Volkers KM, Blankevoort CG, Scherder EJ, Jefferson AL, Steinberg E, Nair A, Green RC, Stern RA. Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer's disease. Objective: To examine differences in lower-extremity function in

  11. Atomic collisions under extreme conditions in space

    International Nuclear Information System (INIS)

    Itikawa, Yukikazu

    1987-01-01

    In space, atoms and molecules are often placed under the extreme conditions which are very difficult to be realized on Earth. For instance, extremely hot and dense plasmas are found in and around various stellar objects (e.g., neutron stars) on one hand and extremely cold and diffuse gases prevail in interstellar space on the other. There is so strong a magnetic field that electron clouds in atoms and molecules are distorted. The study of atomic collisions under the extreme conditions is not only helpful in understanding the astrophysical environment but also reveals new aspects of the physics of atoms and molecules. This paper is an invitation to the study. (References are not exhaustive but only provide a clue with which more details can be found.) (author)

  12. QCD under extreme conditions: an informal discussion

    CERN Document Server

    Fraga, E.S.

    2015-05-22

    We present an informal discussion of some aspects of strong interactions un- der extreme conditions of temperature and density at an elementary level. This summarizes lectures delivered at the 2013 and 2015 CERN – Latin-American Schools of High-Energy Physics and is aimed at students working in experi- mental high-energy physics.

  13. Lower-Extremity Function in Cognitively Healthy Aging, Mild Cognitive Impairment, and Alzheimer's Disease

    NARCIS (Netherlands)

    Eggermont, Laura H.; Gavett, Brandon E.; Volkers, Karin M.; Blankevoort, Christiaan G.; Scherder, Erik J.; Jefferson, Angela L.; Steinberg, Eric; Nair, Anil; Green, Robert C.; Stern, Robert A.

    Eggermont LH, Gavett BE, Volkers KM, Blankevoort CG, Scherder EJ, Jefferson AL, Steinberg E, Nair A, Green RC, Stern RA. Lower-extremity function in cognitively healthy aging, mild cognitive impairment, and Alzheimer's disease. Arch Phys Med Rehabil 2010;91:584-8. Objective: To examine differences

  14. Physics of condensed matter at extreme conditions

    International Nuclear Information System (INIS)

    Ross, M.

    1988-01-01

    The study of matter under extreme conditions is a highly interdisciplinary subject with broad applications to materials science, geophysics and astrophysics. High-pressure properties are studied in the laboratory using static and dynamic techniques. The two differ drastically in the methods of generating and measuring pressure and in the fundamentally different nature of the final compressed state. This article covers a very broad range of conditions, intended to present an overview of important recent developments and to emphasize the behavior of materials and the kinds of properties now being studied

  15. Behavior under Extreme Conditions: The Titanic Disaster

    OpenAIRE

    Bruno S. Frey; David A. Savage; Benno Torgler

    2011-01-01

    During the night of April 14, 1912, the RMS Titanic collided with an iceberg on her maiden voyage. Two hours and 40 minutes later she sank, resulting in the loss of 1,501 lives—more than two-thirds of her 2,207 passengers and crew. This remains one of the deadliest peacetime maritime disasters in history and by far the most famous. For social scientists, evidence about how people behaved as the Titanic sunk offers a quasi-natural field experiment to explore behavior under extreme conditions o...

  16. Methane synthesis under mild conditions for decentralized applications

    International Nuclear Information System (INIS)

    Schlueter, Michael; Roensch, Stefan

    2016-01-01

    It is a central aim of the German government to significantly reduce the emission of greenhouse gases in the next years. One possibility to reach this aim is the substitution of fossil fuels, especially natural gas, by fuels from biogenic sources (Bio-SNG). However, it is a drawback of Bio-SNG that the production costs are considerably higher than those of fossil natural gas. This work provides an approach to reduce the production costs of Bio-SNG. It is the aim to reduce the process parameters of the methane synthesis. At the same time, it has to be ensured that high methane yields are achieved even at those mild conditions. A procedure for the optimization of the methanation catalyst activity will be presented. If the catalyst is as active as possible even at mild conditions, it will be possible to produce Bio-SNG cost efficient even in small, decentralized scale.

  17. Injuries in an Extreme Conditioning Program.

    Science.gov (United States)

    Aune, Kyle T; Powers, Joseph M

    2016-10-19

    Extreme conditioning programs (ECPs) are fitness training regimens relying on aerobic, plyometric, and resistance training exercises, often with high levels of intensity for a short duration of time. These programs have grown rapidly in popularity in recent years, but science describing the safety profile of these programs is lacking. The rate of injury in the extreme conditioning program is greater than the injury rate of weightlifting and the majority of injuries occur to the shoulder and back. Cross-sectional study. Level 4. This is a retrospective survey of injuries reported by athletes participating in an ECP. An injury survey was sent to 1100 members of Iron Tribe Fitness, a gym franchise with 5 locations across Birmingham, Alabama, that employs exercises consistent with an ECP in this study. An injury was defined as a physical condition resulting from ECP participation that caused the athlete to either seek medical treatment, take time off from exercising, or make modifications to his or her technique to continue. A total of 247 athletes (22%) completed the survey. The majority (57%) of athletes were male (n = 139), and 94% of athletes were white (n = 227). The mean age of athletes was 38.9 years (±8.9 years). Athletes reported participation in the ECP for, on average, 3.6 hours per week (± 1.2 hours). Eighty-five athletes (34%) reported that they had sustained an injury while participating in the ECP. A total of 132 injuries were recorded, yielding an estimated incidence of 2.71 per 1000 hours. The shoulder or upper arm was the most commonly injured body site, accounting for 38 injuries (15% of athletes). Athletes with a previous shoulder injury were 8.1 times as likely to injure their shoulder in the ECP compared with athletes with healthy shoulders. The trunk, back, head, or neck (n = 29, 12%) and the leg or knee (n = 29, 12%) were the second most commonly injured sites. The injury incidence rate among athletes with study estimates the incidence of

  18. Tolerances of microorganisms to extreme environmental conditions

    International Nuclear Information System (INIS)

    West, J.M.; Arme, S.C.

    1985-03-01

    Microbial isolates from sites relevant to the disposal of radioactive wastes have been subjected to extreme environmental conditions in order to ascertain their tolerance ability. Two groups were chosen, sulphate reducing bacteria and sulphur oxidising bacteria, because of their potential effects on waste containment. They have been subjected to high temperatures, pressures and radiation (delta-emissions) in optimal media conditions and their ability to tolerate the conditions has been ascertained by epifluorescence microscopy and adenosine tri-phosphate (ATP) analysis followed by 'culture-on' to assess post experimental viability. Results indicate that the sulphate reducers in general, are more tolerant to these conditions than the sulphur oxidisers, some proving to be thermophilic. The sulphate reducer showed increased growth rates, as determined by population numbers, at 50 0 C and survived at 80 0 C, 4,500 psig (310 bar) with no subsequent loss in viability. Gamma irradiation of this group and an isolate of 10 5 rad over 4 hours had no effect on population numbers or viability. Such resistances are not apparent with the sulphur oxidisers whose numbers decreased with increasing radiation dose and are destroyed with pressure. (author)

  19. Injuries in an Extreme Conditioning Program

    Science.gov (United States)

    Aune, Kyle T.; Powers, Joseph M.

    2016-01-01

    Background: Extreme conditioning programs (ECPs) are fitness training regimens relying on aerobic, plyometric, and resistance training exercises, often with high levels of intensity for a short duration of time. These programs have grown rapidly in popularity in recent years, but science describing the safety profile of these programs is lacking. Hypothesis: The rate of injury in the extreme conditioning program is greater than the injury rate of weightlifting and the majority of injuries occur to the shoulder and back. Study Design: Cross-sectional study. Level of Evidence: Level 4. Methods: This is a retrospective survey of injuries reported by athletes participating in an ECP. An injury survey was sent to 1100 members of Iron Tribe Fitness, a gym franchise with 5 locations across Birmingham, Alabama, that employs exercises consistent with an ECP in this study. An injury was defined as a physical condition resulting from ECP participation that caused the athlete to either seek medical treatment, take time off from exercising, or make modifications to his or her technique to continue. Results: A total of 247 athletes (22%) completed the survey. The majority (57%) of athletes were male (n = 139), and 94% of athletes were white (n = 227). The mean age of athletes was 38.9 years (±8.9 years). Athletes reported participation in the ECP for, on average, 3.6 hours per week (± 1.2 hours). Eighty-five athletes (34%) reported that they had sustained an injury while participating in the ECP. A total of 132 injuries were recorded, yielding an estimated incidence of 2.71 per 1000 hours. The shoulder or upper arm was the most commonly injured body site, accounting for 38 injuries (15% of athletes). Athletes with a previous shoulder injury were 8.1 times as likely to injure their shoulder in the ECP compared with athletes with healthy shoulders. The trunk, back, head, or neck (n = 29, 12%) and the leg or knee (n = 29, 12%) were the second most commonly injured sites. The

  20. Renewable Aromatics from the Degradation of Polystyrene under Mild Conditions

    KAUST Repository

    Al Jabri, Nouf M.

    2017-08-01

    Polystyrene (PS) is one of the most important polymers in the plastic sector due to its inexpensive cost as well as many preferred properties. Its international market is expected to achieve $28.2 billion by 2019. Although PS has a high calorific value of 87 GJ tonne-1, there is no a practical method to manage its waste but landfill. As a result, the PS debris in the oceans has reached 70% of the total plastic debris. This issue is considered as the main economical and environmental drivers of converting polystyrene waste into renewable chemical feedstocks. The aim of this work is to develop a catalyst for converting PS into renewable chemicals under mild conditions. We introduce FeCu/Alumina with excellent catalytic activity to fully degrade polystyrene with 66% liquid yield at 250 °C. The GC/MS confirmed that the primary products are in the gasoline range. Next, we present the bimetallic FeCo/Alumina and successfully we have obtained 100% PS conversion and 90% liquid yield with maintaining the products selectivity. Later, the tri-metallic FeCuCo/Alumina was synthesized and showed 100% PS conversion and 91% liquid yield. Surprisingly, ethylbenzene was the major product in which 80 wt. % was achieved with excellent reproducibility. Furthermore, the real waste Styrofoam was thermally and catalytically degraded at 250 °C. Interestingly, a high styrene content of 78 wt. % was recovered after 30 minutes of the reaction under mild conditions. Keeping in mind that a good balance between acidity and basicity is required to convert PS into aromatic under mild reaction conditions catalytically. Finally, the performance of the catalysts was compared to literature reports and showed novel liquid yields. In conclusion, we have synthesized cheap, easy to scale up, and efficient catalysts to fully degrade PS into high liquid yields of aromatics with excellent selectivity.

  1. Performance of blueberry cultivars under mild winter conditions

    Directory of Open Access Journals (Sweden)

    José Gilberto Sousa Medeiros

    2017-08-01

    Full Text Available ABSTRACT: Evaluation of yield performance is important to find the most adapted blueberry cultivars in a particular region. This research aimed to evaluate the flowering and hasvesting periods, the production per plant, and fruit quality of eight rabbiteye blueberry cultivars (Aliceblue, Bluebelle, Bluegem, Briteblue, Climax, Delite, Powderblue, and Woodard and two highbush blueberries (Georgiagem and O’Neal, in mild winter conditions in Pinhais-PR. Flowering and harvesting periods, production, berry weight, size, pH, soluble solids, titratable acidity, ratio and color of the fruits were evaluated in the 2013/2014 and 2014/2015 growing seasons, when the plants had two and three years old, respectively. Cultivars flowered from August to September, and harvest was concentrated in November and December. Berry weight, size, pH, soluble solids and acidity varied among the cultivars. The average ratios of 14.97 and 13.39 for each crop proved that the cultivars have good fruit quality. There was little variation in fruit color in the two years evaluated. Blueberry cultivars showed the staining characteristics and physical and chemical attributes of quality compatible to blueberry from other traditional regions. Under mild winter conditions, young plants of rabbiteye blueberry cultivars, Climax, Delite, Bluegem and Powderblue, are the most productive, while the highbusch cultivars bear few fruits.

  2. Matter Under Extreme Conditions: The Early Years

    Science.gov (United States)

    Keeler, R. Norris; Gibson, Carl H.

    2012-03-01

    Extreme conditions in natural flows are examined, starting with a turbulent big bang. A hydro-gravitational-dynamics cosmology model is adopted. Planck-Kerr turbulence instability causes Planck-particle turbulent combustion. Inertial-vortex forces induce a non-turbulent ki- netic energy cascade to Planck-Kolmogorov scales where vorticity is produced, overcoming 10113 Pa Planck-Fortov pressures. The spinning, expanding fireball has a slight deficit of Planck antiparticles. Space and mass-energy powered by gluon viscous stresses expand exponentially at speeds >1025 c. Turbulent temperature and spin fluctuations fossilize at scales larger than ct, where c is light speed and t is time. Because "dark-energy" antigravity forces vanish when infla- tion ceases, and because turbulence produces entropy, the universe is closed and will collapse and rebound. Density and spin fossils of big bang turbulent mixing trigger structure formation in the plasma epoch. Fragmenting protosuperclustervoids and protoclustervoids produce weak tur- bulence until the plasma-gas transition give chains of protogalaxies with the morphology of tur- bulence. Chain galaxy clusters observed at large redshifts ~8.6 support this interpretation. Pro- togalaxies fragment into clumps, each with a trillion Earth-mass H-He gas planets. These make stars, supernovae, the first chemicals, the first oceans and the first life soon after the cosmologi- cal event.

  3. Ecological and biological systems under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Zlobin, V S; Nenishkiene, V B

    1989-01-01

    The behaviour of biological and ecological systems under extreme conditions (high and low temperatures, electromagnetic fields of different frequencies, ultraviolet. X-ray and gamma radiation) is analyzed. The ecosystems of macro- and microalgae living in salt, brackinsh and fresh waters are considered in the evolutional aspect basing on their chemical and biochemical composition taking into account the mechanism of radionuclide uptake by water plant cells, osmotic regulation, water and ice structures, combined water in a living organism. The problems of life-support in cosmic flights and of mastering the planets of the Solar system, for instance Mars and Venus, utilizing some microalgae and bacteria with high adaptive properties are discussed. Abnormal water points and their role in the metabolism of a water plant cell are estimated. The 'life niches' are determined at the temperatures exceeding 100 deg C and the possibility of existence for living organisms in high pressure and temperature is grounded. Attempts are made to change the metabolism of the plant and animal cell by subjecting it to the action of electromagnetic and thermal fields, heavy water, chemical and pharmocological substances changing the structure of bound water. 333 refs.; 79 tabs.

  4. Community responses to extreme climatic conditions

    Directory of Open Access Journals (Sweden)

    Frédéric JIGUET, Lluis BROTONS, Vincent DEVICTOR

    2011-06-01

    Full Text Available Species assemblages and natural communities are increasingly impacted by changes in the frequency and severity of extreme climatic events. Here we propose a brief overview of expected and demonstrated direct and indirect impacts of extreme events on animal communities. We show that differential impacts on basic biological parameters of individual species can lead to strong changes in community composition and structure with the potential to considerably modify the functional traits of the community. Sudden disequilibria have even been shown to induce irreversible shifts in marine ecosystems, while cascade effects on various taxonomic groups have been highlighted in Mediterranean forests. Indirect effects of extreme climatic events are expected when event-induced habitat changes (e.g. soil stability, vegetation composition, water flows altered by droughts, floods or hurricanes have differential consequences on species assembled within the communities. Moreover, in increasing the amplitude of trophic mismatches, extreme events are likely to turn many systems into ecological traps under climate change. Finally, we propose a focus on the potential impacts of an extreme heat wave on local assemblages as an empirical case study, analysing monitoring data on breeding birds collected in France. In this example, we show that despite specific populations were differently affected by local temperature anomalies, communities seem to be unaffected by a sudden heat wave. These results suggest that communities are tracking climate change at the highest possible rate [Current Zoology 57 (3: 406–413, 2011].

  5. Crenarchaeal biofilm formation under extreme conditions.

    Directory of Open Access Journals (Sweden)

    Andrea Koerdt

    Full Text Available BACKGROUND: Biofilm formation has been studied in much detail for a variety of bacterial species, as it plays a major role in the pathogenicity of bacteria. However, only limited information is available for the development of archaeal communities that are frequently found in many natural environments. METHODOLOGY: We have analyzed biofilm formation in three closely related hyperthermophilic crenarchaeotes: Sulfolobus acidocaldarius, S. solfataricus and S. tokodaii. We established a microtitre plate assay adapted to high temperatures to determine how pH and temperature influence biofilm formation in these organisms. Biofilm analysis by confocal laser scanning microscopy demonstrated that the three strains form very different communities ranging from simple carpet-like structures in S. solfataricus to high density tower-like structures in S. acidocaldarius in static systems. Lectin staining indicated that all three strains produced extracellular polysaccharides containing glucose, galactose, mannose and N-acetylglucosamine once biofilm formation was initiated. While flagella mutants had no phenotype in two days old static biofilms of S. solfataricus, a UV-induced pili deletion mutant showed decreased attachment of cells. CONCLUSION: The study gives first insights into formation and development of crenarchaeal biofilms in extreme environments.

  6. DISAL glycosyl donors for the synthesis of a linear hexasaccharide under mild conditions

    DEFF Research Database (Denmark)

    Petersen, Lars; Laursen, Jane B.; Larsen, K.

    2003-01-01

    The new class of glycosyl donors with a methyl 3,5-dinitrosalicylate (DISAL) anomeric leaving group has proved efficient for glycosylation under strictly neutral, mildly basic, or mildly acidic conditions. Here, we report the synthesis of novel DISAL disaccharide glycosyl donors prepared by easy...... nucleophilic aromatic substitution. These DISAL donors proved efficient in the synthesis of a starch-related hexasaccharide under very mild conditions. Glycosylations proceeded with alpha-selectivity and were compatible with Trt protecting groups....

  7. Baryon number nonconservation in extreme conditions

    International Nuclear Information System (INIS)

    Matveev, V.A.; Rubakov, V.A.; Tavkhelidze, A.N.; Shaposhnikov, M.E.

    1988-01-01

    In gauge theories with the left-right asymmetric fermionic content (e.g. in standard electroweak theory) fermion number F is not conserved due to the anomaly. It is shown that anomalous processes, while being exponentially suppressed, under normal conditions, are in fact rapid. The mechanism of fermionic number nonconservation connected with a level crossing phenomenon in external gauge fields is described. The theory and experimental consequences of monopole catalysis of a proton decay is reviewed. It is shown that cold dense fermionic matter is stable only up to some limiting density. It is demonstrated that there is no exponential suppression of the rate F nonconservation at high temperatures. The cosmological implications of this fact are discussed. The strong anomalous fermionic number violation in decays of superheavy fermions technibaryons is considered

  8. Effective interactions for extreme isospin conditions; Interactions effectives pour des conditions extremes d`isospin

    Energy Technology Data Exchange (ETDEWEB)

    Chabanat, E.

    1995-01-01

    One of the main goal in nuclear physics research is the study of nuclei in extreme conditions of spin and isospin. The more performing tools for theoretical predictions in this field are microscopic methods such as the Hartree-Fock one based on independent particle approximation. The main ingredient for such an approach is the effective nucleon-nucleon interaction. The actual trend being the study of nuclei more and more far from the stability valley, it is necessary to cast doubt over the validity of usual effective interaction. This work constitute a study on the way one can construct a new interaction allowing some theoretical predictions on nuclei far from the stability. We have thus made a complete study of symmetric infinite nuclear matter and asymmetric one up to pure neutron matter. One shows that the asymmetry coefficient, which was considered until now as fixing isospin properties, is not sufficient to have a correct description of very exotic isospin states. A new type of constraint is shown for fixing this degree of freedom: the neutron matter equation of state. One include this equation of state, taken from a theoretical model giving a good description of radii and masses of neutron stars. One can thus expect to build up new Skyrme interaction with realistic properties of ground state of very neutron-rich nuclei. (author). 63 refs., 68 figs., 15 tabs.

  9. Thermal properties of bentonite under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Vasicek, R. [Czech Technical Univ., Centre of Experimental Geotechnics, Faculty of Civil Engineering, Prague (Czech Republic)

    2005-07-01

    Centre of Experimental Geotechnics (CEG) deals with the research of the behaviour of bentonite and clays. The measurement of thermal properties is not so frequent test in geotechnical laboratory but in relation to deep repository it is a part which should not be overlooked. The reason is the heat generated by canister with spent nuclear fuel and possible influence of the heat on the materials of the engineered barrier. In the initial stages following the burial of canister with the waste the barrier materials will be exposed to elevated temperature. According to existing information, these temperatures should not exceed 90 C. That heat can induce a creation of cracks and opening of joint between highly compacted blocks. It will predispose the bentonite barrier to penetration of water from surrounding towards to canister. Therefore easy removal of heat through the barrier is required. It is essential that the tests aimed at determining the real values of measured parameters are carried out in conditions identical with those anticipated in a future disposal system. These relatively complicated thermophysical tests are logical continuation of the simple ones, carried out under laboratory temperature and on not fully saturated samples without possibility to measure the swelling pressure. Thermophysical properties and swelling pressure are dominantly influenced by water content (which is influenced by temperature). Therefore is important to realize the tests under different moisture and thermal conditions. These tests are running at the APT-PO1 Analyser, designed to fulfill mentioned requirements - it allows measurement of thermal properties under temperature up to 200 C and swelling pressure up to 20 MPa. The device is capable to register the evolution of temperature, swelling and vapor pressure. The measurement of thermal conductivity and volume heat capacity is realized by the dynamic impulse method with point source of heat. Four types of tests are possible: at

  10. [Guidelines on asthma in extreme environmental conditions].

    Science.gov (United States)

    Drobnic, Franchek; Borderías Clau, Luis

    2009-01-01

    Asthma is a highly prevalent chronic disease which, if not properly controlled, can limit the patient's activities and lifestyle. In recent decades, owing to the diffusion of educational materials, the application of clinical guidelines and, most importantly, the availability of effective pharmacological treatment, most patients with asthma are now able to lead normal lives. Significant social changes have also taken place during the same period, including more widespread pursuit of sporting activities and tourism. As a result of these changes, individuals with asthma can now participate in certain activities that were inconceivable for these patients only a few years ago, including winter sports, underwater activities, air flight, and travel to remote places with unusual environmental conditions (deserts, high mountain environments, and tropical regions). In spite of the publication of several studies on this subject, our understanding of the effects of these situations on patients with asthma is still limited. The Spanish Society of Pulmonology and Thoracic Surgery (SEPAR) has decided to publish these recommendations based on the available evidence and expert opinion in order to provide information on this topic to both doctors and patients and to avert potentially dangerous situations that could endanger the lives of these patients.

  11. Emissions of NO and CO from counterflow combustion of CH4 under MILD and oxyfuel conditions

    International Nuclear Information System (INIS)

    Cheong, Kin-Pang; Li, Pengfei; Wang, Feifei; Mi, Jianchun

    2017-01-01

    This paper reports on the NO and CO emission characteristics of counterflow combustion of methane simulated under MILD or/and oxyfuel conditions. Simulations using CHEMKIN are conducted for various injection conditions of fuel and oxidizer. Note that the terms “oxyfuel”, “MILD-N 2 ” and “MILD-CO 2 ” combustion adopted hereafter represent the conventional oxy-combustion and those MILD combustions diluted by N 2 and CO 2 , respectively. It is observed that the NO emission of MILD-CO 2 combustion is ultra-low for all cases of investigation, even when increasing the combustion temperature up to 2000 K or adding more N 2 (up to 20%) to either the fuel stream (to simulate nitrogen-containing fuels like biomass) or the oxidizer stream (to simulate the air-ingress). A higher temperature allowed under MILD-CO 2 combustion suggests the improvement of energy efficiency for the MILD combustion technology. Moreover, the presence of steam in the oxidant reduces both NO and CO emissions of combustion for all cases. The relative importance analysis reveals that the N 2 O-intermediate mechanism for producing NO prevails in MILD-CO 2 combustion while the prompt and thermal mechanisms predominate MILD-N 2 and oxyfuel combustion, respectively. In addition, the sensitivity analysis identifies those main reactions that play important roles for the NO emission under these combustion conditions. - Highlights: • Assessing the NO and CO emissions from MILD combustion diluted by CO 2 . • Examining the possibility of higher combustion intensity in MILD-CO 2 combustion than in MILD-N 2 combustion. • Differentiating the contributions from each NO mechanism to the total NO emission. • Revealing major NO mechanisms under different combustion conditions. • Better understanding the NO formation mechanisms under MILD combustion.

  12. Response of Simple, Model Systems to Extreme Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Ewing, Rodney C. [Univ. of Michigan, Ann Arbor, MI (United States); Lang, Maik [Univ. of Michigan, Ann Arbor, MI (United States)

    2015-07-30

    The focus of the research was on the application of high-pressure/high-temperature techniques, together with intense energetic ion beams, to the study of the behavior of simple oxide systems (e.g., SiO2, GeO2, CeO2, TiO2, HfO2, SnO2, ZnO and ZrO2) under extreme conditions. These simple stoichiometries provide unique model systems for the analysis of structural responses to pressure up to and above 1 Mbar, temperatures of up to several thousands of kelvin, and the extreme energy density generated by energetic heavy ions (tens of keV/atom). The investigations included systematic studies of radiation- and pressure-induced amorphization of high P-T polymorphs. By studying the response of simple stoichiometries that have multiple structural “outcomes”, we have established the basic knowledge required for the prediction of the response of more complex structures to extreme conditions. We especially focused on the amorphous state and characterized the different non-crystalline structure-types that result from the interplay of radiation and pressure. For such experiments, we made use of recent technological developments, such as the perforated diamond-anvil cell and in situ investigation using synchrotron x-ray sources. We have been particularly interested in using extreme pressures to alter the electronic structure of a solid prior to irradiation. We expected that the effects of modified band structure would be evident in the track structure and morphology, information which is much needed to describe theoretically the fundamental physics of track-formation. Finally, we investigated the behavior of different simple-oxide, composite nanomaterials (e.g., uncoated nanoparticles vs. core/shell systems) under coupled, extreme conditions. This provided insight into surface and boundary effects on phase stability under extreme conditions.

  13. Renewable Aromatics from the Degradation of Polystyrene under Mild Conditions

    KAUST Repository

    Jabri, Nouf M; Lai, Zhiping; Hadjichristidis, Nikolaos; Huang, Kuo-Wei

    2017-01-01

    reactor without distillation. A liquid yield of 66% in an inert environment was achieved without the formation of coke and gas by-products. An exposure time of 90 min. and a catalyst loading of 200 mg were considered as an optimum condition to minimize

  14. Sales down due to particularly mild climatic conditions

    International Nuclear Information System (INIS)

    2007-01-01

    Paris, 27 July 2007 - For the six months to 30 June 2007, Gaz de France's consolidated sales amounted to euro 13,778 million, down 11 per cent compared to the same period in 2006. This performance continues the trend seen over the first quarter of 2007 and in particular reflects the continuation into the second quarter of the climatic factors that affected the start of the year: an exceptionally warm 2006/2007 winter, followed by a spring season with particularly high temperatures. The average temperature of the first half of 2007 corresponds to a heat risk of less than one per cent, meaning that the probability of such a temperature taking place is less than one per cent. Over the first half of the year, volumes distributed in France were down by 25 TWh compared to a comparable period with average weather conditions, whereas in 2006 they were 15 TWh above average. The impact of the weather had similar effects outside of France. Under average weather conditions, the downturn in Group sales was limited to only 0.8 per cent mainly due to market conditions made difficult by the climate, leading to a lower level of gas production and arbitrage activities. Over the first six months of 2007, the Group sought to: - Continue to strengthen its international presence, currently with euro 5,602 million in sales outside of France. The percentage of sales generated outside of France represented 41 per cent of the Group total at the end of June 2007 and increased by 4 percentage points between the first half of 2006 and the first half of 2007. - Prepare for the deregulation of the markets on 1 July 2007 and a new commercial policy for retail customers that has been built around multi-energy and multi-service market offerings. - Create a new subsidiary for the distribution, a process which will be effective at the end of the year as announced. In spite of this unfavourable context, the Group maintains the financial objective for 2007 presented with the 2006 accounts: '2007 will

  15. Sales down due to particularly mild climatic conditions

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2007-07-01

    Paris, 27 July 2007 - For the six months to 30 June 2007, Gaz de France's consolidated sales amounted to euro 13,778 million, down 11 per cent compared to the same period in 2006. This performance continues the trend seen over the first quarter of 2007 and in particular reflects the continuation into the second quarter of the climatic factors that affected the start of the year: an exceptionally warm 2006/2007 winter, followed by a spring season with particularly high temperatures. The average temperature of the first half of 2007 corresponds to a heat risk of less than one per cent, meaning that the probability of such a temperature taking place is less than one per cent. Over the first half of the year, volumes distributed in France were down by 25 TWh compared to a comparable period with average weather conditions, whereas in 2006 they were 15 TWh above average. The impact of the weather had similar effects outside of France. Under average weather conditions, the downturn in Group sales was limited to only 0.8 per cent mainly due to market conditions made difficult by the climate, leading to a lower level of gas production and arbitrage activities. Over the first six months of 2007, the Group sought to: - Continue to strengthen its international presence, currently with euro 5,602 million in sales outside of France. The percentage of sales generated outside of France represented 41 per cent of the Group total at the end of June 2007 and increased by 4 percentage points between the first half of 2006 and the first half of 2007. - Prepare for the deregulation of the markets on 1 July 2007 and a new commercial policy for retail customers that has been built around multi-energy and multi-service market offerings. - Create a new subsidiary for the distribution, a process which will be effective at the end of the year as announced. In spite of this unfavourable context, the Group maintains the financial objective for 2007 presented with the 2006 accounts: &apos

  16. Existence of mild solutions of a semilinear evolution differential inclusions with nonlocal conditions

    Directory of Open Access Journals (Sweden)

    Reem A. Al-Omair

    2009-03-01

    Full Text Available In this paper we prove the existence of a mild solution for a semilinear evolution differential inclusion with nonlocal condition and governed by a family of linear operators, not necessarily bounded or closed, in a Banach space. No compactness assumption is assumed on the evolution operator generated by the family operators. Also, we prove that the set of mild solutions is compact.

  17. Renewable Aromatics from the Degradation of Polystyrene under Mild Conditions

    KAUST Repository

    Jabri, Nouf M

    2017-05-25

    A bimetallic FeCu/alumina catalyst was prepared and characterized. It showed excellent catalytic activity to quantitatively convert polystyrene (PS) into aromatics at low temperatures. A clear goldish yellow liquid was produced at 250 °C in a batch reactor without distillation. A liquid yield of 66% in an inert environment was achieved without the formation of coke and gas by-products. An exposure time of 90 min. and a catalyst loading of 200 mg were considered as an optimum condition to minimize the styrene re-polymerization. The gas chromatography/ mass spectrometry (GC/MS) analysis confirms that the primary products are styrene, ethylbenzene, cumene, toluene and α-methylstyrene.

  18. Renewable aromatics from the degradation of polystyrene under mild conditions

    Directory of Open Access Journals (Sweden)

    Nouf M. Aljabri

    2017-12-01

    Full Text Available A bimetallic FeCu/alumina catalyst was prepared and characterized. It showed excellent catalytic activity to quantitatively convert polystyrene (PS into aromatics at low temperatures. A clear goldish yellow liquid was produced at 250 °C in a batch reactor without distillation. A liquid yield of 66% in an inert environment was achieved without the formation of coke and gas by-products. An exposure time of 90 min. and a catalyst loading of 200 mg were considered as an optimum conditions to minimize the styrene re-polymerization. The gas chromatography/mass spectrometry (GC/MS analysis confirms that the primary products are styrene, ethylbenzene, cumene, toluene and α-methylstyrene. Keywords: Polystyrene, Bimetallic, Low-temperature, Catalytic degradation

  19. The Formation of Fe/Mg Smectite Under Mildly Acidic Conditions on Early Mars

    Science.gov (United States)

    Sutter, B.; Golden, D. C.; Ming, Douglas W.; Niles, P. B.

    2011-01-01

    The detection of Fe/Mg smectites and carbonate in Noachian and early Hesperian terrain of Mars suggests that neutral to mildly alkaline conditions prevailed during the early history of Mars. If early Mars surface geochemical conditions were neutral to moderately alkaline with a denser CO2 atmosphere than today, then large carbonates deposits should be more widely detected in Noachian terrain. Why have so few carbonate deposits been detected compared to Fe/Mg smectites? Fe/Mg smectites on early Mars formed under mildly acidic conditions, which would preclude the extensive formation of carbonate deposits. The goal of the proposed work is to evaluate the formation of Fe/Mg smectites under mildly acidic conditions.

  20. Ultrasonic Technique for Density Measurement of Liquids in Extreme Conditions

    Directory of Open Access Journals (Sweden)

    Rymantas Kazys

    2015-08-01

    Full Text Available An ultrasonic technique, invariant to temperature changes, for a density measurement of different liquids under in situ extreme conditions is presented. The influence of geometry and material parameters of the measurement system (transducer, waveguide, matching layer on measurement accuracy and reliability is analyzed theoretically along with experimental results. The proposed method is based on measurement of the amplitude of the ultrasonic wave, reflected from the interface of the solid/liquid medium under investigation. In order to enhance sensitivity, the use of a quarter wavelength acoustic matching layer is proposed. Therefore, the sensitivity of the measurement system increases significantly. Density measurements quite often must be performed in extreme conditions at high temperature (up to 220 °C and high pressure. In this case, metal waveguides between piezoelectric transducer and the measured liquid are used in order to protect the conventional transducer from the influence of high temperature and to avoid depolarization. The presented ultrasonic density measurement technique is suitable for density measurement in different materials, including liquids and polymer melts in extreme conditions. A new calibration algorithm was proposed. The metrological evaluation of the measurement method was performed. The expanded measurement uncertainty Uρ = 7.4 × 10−3 g/cm3 (1%.

  1. Ultrasonic Technique for Density Measurement of Liquids in Extreme Conditions

    Science.gov (United States)

    Kazys, Rymantas; Sliteris, Reimondas; Rekuviene, Regina; Zukauskas, Egidijus; Mazeika, Liudas

    2015-01-01

    An ultrasonic technique, invariant to temperature changes, for a density measurement of different liquids under in situ extreme conditions is presented. The influence of geometry and material parameters of the measurement system (transducer, waveguide, matching layer) on measurement accuracy and reliability is analyzed theoretically along with experimental results. The proposed method is based on measurement of the amplitude of the ultrasonic wave, reflected from the interface of the solid/liquid medium under investigation. In order to enhance sensitivity, the use of a quarter wavelength acoustic matching layer is proposed. Therefore, the sensitivity of the measurement system increases significantly. Density measurements quite often must be performed in extreme conditions at high temperature (up to 220 °C) and high pressure. In this case, metal waveguides between piezoelectric transducer and the measured liquid are used in order to protect the conventional transducer from the influence of high temperature and to avoid depolarization. The presented ultrasonic density measurement technique is suitable for density measurement in different materials, including liquids and polymer melts in extreme conditions. A new calibration algorithm was proposed. The metrological evaluation of the measurement method was performed. The expanded measurement uncertainty Uρ = 7.4 × 10−3 g/cm3 (1%). PMID:26262619

  2. Ultrasonic Technique for Density Measurement of Liquids in Extreme Conditions.

    Science.gov (United States)

    Kazys, Rymantas; Sliteris, Reimondas; Rekuviene, Regina; Zukauskas, Egidijus; Mazeika, Liudas

    2015-08-07

    An ultrasonic technique, invariant to temperature changes, for a density measurement of different liquids under in situ extreme conditions is presented. The influence of geometry and material parameters of the measurement system (transducer, waveguide, matching layer) on measurement accuracy and reliability is analyzed theoretically along with experimental results. The proposed method is based on measurement of the amplitude of the ultrasonic wave, reflected from the interface of the solid/liquid medium under investigation. In order to enhance sensitivity, the use of a quarter wavelength acoustic matching layer is proposed. Therefore, the sensitivity of the measurement system increases significantly. Density measurements quite often must be performed in extreme conditions at high temperature (up to 220 °C) and high pressure. In this case, metal waveguides between piezoelectric transducer and the measured liquid are used in order to protect the conventional transducer from the influence of high temperature and to avoid depolarization. The presented ultrasonic density measurement technique is suitable for density measurement in different materials, including liquids and polymer melts in extreme conditions. A new calibration algorithm was proposed. The metrological evaluation of the measurement method was performed. The expanded measurement uncertainty Uρ = 7.4 × 10(-3) g/cm(3) (1%).

  3. Wireless pilot monitoring system for extreme race conditions.

    Science.gov (United States)

    Pino, Esteban J; Arias, Diego E; Aqueveque, Pablo; Melin, Pedro; Curtis, Dorothy W

    2012-01-01

    This paper presents the design and implementation of an assistive device to monitor car drivers under extreme conditions. In particular, this system is designed in preparation for the 2012 Atacama Solar Challenge to be held in the Chilean desert. Actual preliminary results show the feasibility of such a project including physiological and ambient sensors, real-time processing algorithms, wireless data transmission and a remote monitoring station. Implementation details and field results are shown along with a discussion of the main problems found in real-life telemetry monitoring.

  4. Formation of the Imidazolinone Ring Under Mild Conditions in the Presence of Sodium Hydride

    Directory of Open Access Journals (Sweden)

    Anibal J. Mocchi

    2004-06-01

    Full Text Available Substituted imidazolinones containing heterocyclic carboxylic acids as substituents and possessing herbicidal properties were synthesized by cyclization of 2-amino-2,3-dimethylbutyramide with heterocyclic ethyl dicarboxylates under mild conditions. The use of NaH as base leads to a significant increase in the reaction rate and allows the preparation of the target compounds in high yields.

  5. Proceedings of the workshop on scattering experiments under extreme conditions

    International Nuclear Information System (INIS)

    Sakai, N.; Ikeda, H.; Ando, M.

    1991-10-01

    In the National Laboratory for High Energy Physics (KEK), as the research facilities, there are Photon Factory, the facility for utilizing the booster and University of Tokyo Meson Science Research Center. For the research on physical properties, it is very important to do structural analysis in a broad sense and to observe the behavior of quasiparticles in solids. The X-ray and pulsed neutrons required for these researches can be obtained in a single laboratory in KEK, and it is rare in the world. At this opportunity of the workshop on scattering experiments under extreme conditions, it is hoped that the positive interchange between both PF and booster groups will be carried out. The research on magnetic substances using X-ray is a most noteworthy utilization of synchrotron radiation. The discovery of X-ray resonance magnetic scattering by K. Namikawa is one of the remarkable researches using synchrotron radiation in the world. When the extreme conditions around samples are prepared, the quality of signals for the research on physical properties is to be heightened. In this report, the researches on physical properties under ultrahigh pressure and ultralow temperature are reported. (K.I.)

  6. Triticale in the years with extreme weather conditions

    Directory of Open Access Journals (Sweden)

    Nožinić Miloš

    2009-01-01

    Full Text Available Unlike other grain crops, the area under triticale in the Republic of Srpska has been expanding every year. Since the introduction of this plant species in the broad production began a few years ago, the finding of the optimal variety agrotechnique in different environmental conditions has great importance. This paper deals with the results of the trials from seven locations in two very extreme vegetation seasons (2002/03, 2006/07. High yield of triticale on the location Banja Luka (150 m alt. with five triticale varieties in four sowing rates in the replication trial in very unfavorable weather conditions in 2003, points to emphasized triticale tolerance to high temperatures and drought. High grain yield of triticale in the trials on the locations Banja Luka, Butmir (460 m alt. and Živince (230 m alt. was obtained in 2007 too, when all vegetation months had higher mean temperature than long term average, what is a unique appearance in the entire 'meteorological history'. In the paper the appearance of the earliest triticale heading is described and explained. It happened at one production trial on Manjača (250 m alt. in the first decade of March in 2007. On the another location on Manjača (450 m alt., in the macrotrial, rye showed much higher tolerance to extreme soil acidity, than triticale. Obtained results and unusual appearances on triticale are helpful for the further research of the stability and adaptability of more important triticale traits. .

  7. Acupuncture Combined with Hydrotherapy in Diabetes Patients with Mild Lower-Extremity Arterial Disease: A Prospective, Randomized, Nonblinded Clinical Study.

    Science.gov (United States)

    Qi, Zhengqin; Pang, Yan; Lin, Lin; Zhang, Bing; Shao, Juntao; Liu, Xiaodong; Zhang, Xin

    2018-05-08

    BACKGROUND The aim of this pragmatic study was to explore the intervention of acupuncture combined with hydrotherapy and perceived effects in type 2 diabetic patients with recently diagnosed, mild, lower-extremity arterial disease (LEAD) in comparison with a control group. MATERIAL AND METHODS One hundred twenty-six diabetes patients who were diagnosed mild LEAD according to ankle-brachial blood pressure index (ABPI) and peripheral neuropathy symptom were randomly assigned to either an experimental (n=64) or control group (n=62). The experimental group attended and completed (1) a 30-min session of acupuncture in certain selected points, and (2) a 30-min hydrotherapy exercise every 2 days for 15 weeks. The outcome parameters were assessed at baseline, after intervention, and at 6-week follow-up. RESULTS The intervention was associated with an improvement in leg flow conductance and partial physical capacities, including chair-sit-and-reach, the walking impairment questionnaire (WIQ), and physical component summary score (PCS), compared to the control group. The treatment benefits were sustained throughout the 6-week follow-up endpoint. There was no difference in fasting glucose levels, Hb1Ac, blood pressure, or BMI after the intervention. At the endpoint of 6-week follow-up, acupuncture plus hydrotherapy appeared to reduce inflammatory response by decreasing IL-6, TNF-α, malondialdehyde, and SOD, and increasing glutathione. CONCLUSIONS Acupuncture plus hydrotherapy, without significant glycemic-controlling effects in the type 2 diabetic patients with mild LEAD, exerts a measurable benefit in disease-specific physical functions and health-related quality of life. Our results suggest that the combined therapy regulates the inflammatory process and oxidative stress and contributes to immune protection.

  8. Molecular Mechanisms of Survival Strategies in Extreme Conditions

    Directory of Open Access Journals (Sweden)

    Federica Migliardo

    2012-12-01

    Full Text Available Today, one of the major challenges in biophysics is to disclose the molecular mechanisms underlying biological processes. In such a frame, the understanding of the survival strategies in extreme conditions received a lot of attention both from the scientific and applicative points of view. Since nature provides precious suggestions to be applied for improving the quality of life, extremophiles are considered as useful model-systems. The main goal of this review is to present an overview of some systems, with a particular emphasis on trehalose playing a key role in several extremophile organisms. The attention is focused on the relation among the structural and dynamic properties of biomolecules and bioprotective mechanisms, as investigated by complementary spectroscopic techniques at low- and high-temperature values.

  9. Methane synthesis under mild conditions for decentralized applications; Methansynthese unter milden Bedingungen fuer dezentrale Anwendungen

    Energy Technology Data Exchange (ETDEWEB)

    Schlueter, Michael [DBFZ Deutsches Biomasseforschungszentrum gGmbH, Leipzig (Germany); Roensch, Stefan

    2016-08-01

    It is a central aim of the German government to significantly reduce the emission of greenhouse gases in the next years. One possibility to reach this aim is the substitution of fossil fuels, especially natural gas, by fuels from biogenic sources (Bio-SNG). However, it is a drawback of Bio-SNG that the production costs are considerably higher than those of fossil natural gas. This work provides an approach to reduce the production costs of Bio-SNG. It is the aim to reduce the process parameters of the methane synthesis. At the same time, it has to be ensured that high methane yields are achieved even at those mild conditions. A procedure for the optimization of the methanation catalyst activity will be presented. If the catalyst is as active as possible even at mild conditions, it will be possible to produce Bio-SNG cost efficient even in small, decentralized scale.

  10. Exertional Rhabdomyolysis after an Extreme Conditioning Competition: A Case Report

    Directory of Open Access Journals (Sweden)

    Ramires Alsamir Tibana

    2018-04-01

    Full Text Available This case report describes an instance of exercise-induced rhabdomyolysis caused by an extreme conditioning program (ECP competition. A 35-year-old female presented with abdominal pain and soreness, which began one day after she completed two days of ECPcompetition composed of five workouts. Three days after competition, creatine kinase (CK was 77,590 U/L accompanied by myalgia and abnormal liver function tests, while renal function was normal and this resulted in a diagnosis of rhabdomyolysis. A follow-up examination revealed that her serum level of CK was still elevated to 3034 U/L on day 10 and 1257 U/L on day 25 following the ECP competition. The subject reported myalgia even up to 25 days after the ECP competition. Exertional rhabdomyolysis can be observed in ECP athletes following competition and highlights a dangerous condition, which may be increasing in recent years due to the massive expansion of ECP popularity and a growing number of competitions. Future research should investigate the causes of rhabdomyolysis that occur as a result of ECP, especially training methods and/or tasks developed specifically for these competitions.

  11. Safety analysis of casks under extreme impact conditions

    International Nuclear Information System (INIS)

    Wieser, G.; Qiao, L.; Voelzke, H.; Wolff, D.; Droste, B.

    2004-01-01

    The determination of the inherent safety of casks under extreme impact conditions has been of increasing interest since the terrorist attacks of 11 September 2001. For nearly three decades BAM has been investigating cask safety under severe accident conditions like drop tests from more than 9 m onto different targets and without impact limiters as well as artificially damaged prototype casks. One of the most critical scenarios for a cask is the centric impact of a dynamic load onto the lid-seal system. This can be caused, for example, by a direct aircraft crash (or just its engine) as well as by an impact due to the collapse of a building, e.g. a nuclear facility storage hall. In this context BAM is developing methods to calculate the deformation of cask components and-with respect to leak-tightness-relative displacements between the metallic seals and their counterparts. This paper presents reflections on modelling of cask structures for finite-element analyses and discusses calculated results of stresses and deformations. Another important aspect is the behaviour of a cask under a lateral impact by aircraft or fragments of a building. Examples of the kinetic reaction (cask acceleration due to the fragments, subsequent contact with neighbouring structures like the ground, buildings or casks) are shown and discussed in correlation to cask stresses which are to be expected. (author)

  12. Safety analysis of casks under extreme impact conditions

    International Nuclear Information System (INIS)

    Wieser, G.; Qiao Linan; Voelzke, H.; Wolff, D.; Droste, B.

    2004-01-01

    The determination of the inherent safety of casks also under extreme impact conditions has been of increasing interest since the terrorist attacks from 11th September 2001. For nearly three decades BAM has been investigating cask safety under severe accident conditions like drop tests from more than 9 m onto different targets and without impact limiters as well as artificially damaged prototype casks. One of the most critical scenarios for a cask is the centric impact of a dynamic load onto the lid seal system. This can be caused e.g. by direct aircraft crash or its engine as well as by an impact due to the collapse of a building e.g. a nuclear facility storage hall. In this context BAM is developing methods to calculate the deformation of cask components and - with respect to leak tightness - relative displacements between the metallic seals and their counterparts. This paper presents reflections on modelling of cask structures for Finite Element analyses and discusses calculated results of stresses and deformations. Another important aspect is the behaviour of a cask under a lateral impact by aircraft and fragments of a building. Examples of the kinetic reaction (cask acceleration due to the fragments, subsequent contact with neighbouring structures like ground, buildings or casks) are shown and discussed in correlation to cask stresses which are to be expected

  13. Convenient and General Zinc‐Catalyzed Borylation of Aryl Diazonium Salts and Aryltriazenes under Mild Conditions

    Science.gov (United States)

    Qi, Xinxin; Jiang, Li‐Bing; Zhou, Chao; Peng, Jin‐Bao

    2017-01-01

    Abstract A convenient and general zinc‐catalyzed borylation of aryl diazonium salts and aryltriazenes has been developed. With bis‐ (pinacolato)diboron as the borylation reagent, aryldiazonium tetrafluoroborate salts and aryltriazenes were transformed into the corresponding arylboronates in moderate to excellent yields under mild conditions. As a convenient and practical methodology, no additional ligands, base, or any other additives are required here. PMID:28638765

  14. Fast Curing Bio-Based Phenolic Resins via Lignin Demethylated under Mild Reaction Condition

    OpenAIRE

    Jiongjiong Li; Jizhi Zhang; Shifeng Zhang; Qiang Gao; Jianzhang Li; Wei Zhang

    2017-01-01

    Demethylation technique has been used to enhance lignin reactivity for preparation of phenolic resins. However, the demethylation efficiency and the demethylated lignin (DL) reactivity were still unsatisfactory. To improve the demethylation efficiency, alkali lignin was demethylated under different mild conditions using sodium sulfite as a catalyst. Lignin and DL were characterized by 1H-NMR (nuclear magnetic resonance) and Fourier transform infrared (FT-IR) spectroscopy to determine the deme...

  15. Extreme hydrothermal conditions at an active plate-bounding fault

    Science.gov (United States)

    Sutherland, Rupert; Townend, John; Toy, Virginia; Upton, Phaedra; Coussens, Jamie; Allen, Michael; Baratin, Laura-May; Barth, Nicolas; Becroft, Leeza; Boese, Carolin; Boles, Austin; Boulton, Carolyn; Broderick, Neil G. R.; Janku-Capova, Lucie; Carpenter, Brett M.; Célérier, Bernard; Chamberlain, Calum; Cooper, Alan; Coutts, Ashley; Cox, Simon; Craw, Lisa; Doan, Mai-Linh; Eccles, Jennifer; Faulkner, Dan; Grieve, Jason; Grochowski, Julia; Gulley, Anton; Hartog, Arthur; Howarth, Jamie; Jacobs, Katrina; Jeppson, Tamara; Kato, Naoki; Keys, Steven; Kirilova, Martina; Kometani, Yusuke; Langridge, Rob; Lin, Weiren; Little, Timothy; Lukacs, Adrienn; Mallyon, Deirdre; Mariani, Elisabetta; Massiot, Cécile; Mathewson, Loren; Melosh, Ben; Menzies, Catriona; Moore, Jo; Morales, Luiz; Morgan, Chance; Mori, Hiroshi; Niemeijer, Andre; Nishikawa, Osamu; Prior, David; Sauer, Katrina; Savage, Martha; Schleicher, Anja; Schmitt, Douglas R.; Shigematsu, Norio; Taylor-Offord, Sam; Teagle, Damon; Tobin, Harold; Valdez, Robert; Weaver, Konrad; Wiersberg, Thomas; Williams, Jack; Woodman, Nick; Zimmer, Martin

    2017-06-01

    Temperature and fluid pressure conditions control rock deformation and mineralization on geological faults, and hence the distribution of earthquakes. Typical intraplate continental crust has hydrostatic fluid pressure and a near-surface thermal gradient of 31 ± 15 degrees Celsius per kilometre. At temperatures above 300-450 degrees Celsius, usually found at depths greater than 10-15 kilometres, the intra-crystalline plasticity of quartz and feldspar relieves stress by aseismic creep and earthquakes are infrequent. Hydrothermal conditions control the stability of mineral phases and hence frictional-mechanical processes associated with earthquake rupture cycles, but there are few temperature and fluid pressure data from active plate-bounding faults. Here we report results from a borehole drilled into the upper part of the Alpine Fault, which is late in its cycle of stress accumulation and expected to rupture in a magnitude 8 earthquake in the coming decades. The borehole (depth 893 metres) revealed a pore fluid pressure gradient exceeding 9 ± 1 per cent above hydrostatic levels and an average geothermal gradient of 125 ± 55 degrees Celsius per kilometre within the hanging wall of the fault. These extreme hydrothermal conditions result from rapid fault movement, which transports rock and heat from depth, and topographically driven fluid movement that concentrates heat into valleys. Shear heating may occur within the fault but is not required to explain our observations. Our data and models show that highly anomalous fluid pressure and temperature gradients in the upper part of the seismogenic zone can be created by positive feedbacks between processes of fault slip, rock fracturing and alteration, and landscape development at plate-bounding faults.

  16. Extreme hydrothermal conditions at an active plate-bounding fault.

    Science.gov (United States)

    Sutherland, Rupert; Townend, John; Toy, Virginia; Upton, Phaedra; Coussens, Jamie; Allen, Michael; Baratin, Laura-May; Barth, Nicolas; Becroft, Leeza; Boese, Carolin; Boles, Austin; Boulton, Carolyn; Broderick, Neil G R; Janku-Capova, Lucie; Carpenter, Brett M; Célérier, Bernard; Chamberlain, Calum; Cooper, Alan; Coutts, Ashley; Cox, Simon; Craw, Lisa; Doan, Mai-Linh; Eccles, Jennifer; Faulkner, Dan; Grieve, Jason; Grochowski, Julia; Gulley, Anton; Hartog, Arthur; Howarth, Jamie; Jacobs, Katrina; Jeppson, Tamara; Kato, Naoki; Keys, Steven; Kirilova, Martina; Kometani, Yusuke; Langridge, Rob; Lin, Weiren; Little, Timothy; Lukacs, Adrienn; Mallyon, Deirdre; Mariani, Elisabetta; Massiot, Cécile; Mathewson, Loren; Melosh, Ben; Menzies, Catriona; Moore, Jo; Morales, Luiz; Morgan, Chance; Mori, Hiroshi; Niemeijer, Andre; Nishikawa, Osamu; Prior, David; Sauer, Katrina; Savage, Martha; Schleicher, Anja; Schmitt, Douglas R; Shigematsu, Norio; Taylor-Offord, Sam; Teagle, Damon; Tobin, Harold; Valdez, Robert; Weaver, Konrad; Wiersberg, Thomas; Williams, Jack; Woodman, Nick; Zimmer, Martin

    2017-06-01

    Temperature and fluid pressure conditions control rock deformation and mineralization on geological faults, and hence the distribution of earthquakes. Typical intraplate continental crust has hydrostatic fluid pressure and a near-surface thermal gradient of 31 ± 15 degrees Celsius per kilometre. At temperatures above 300-450 degrees Celsius, usually found at depths greater than 10-15 kilometres, the intra-crystalline plasticity of quartz and feldspar relieves stress by aseismic creep and earthquakes are infrequent. Hydrothermal conditions control the stability of mineral phases and hence frictional-mechanical processes associated with earthquake rupture cycles, but there are few temperature and fluid pressure data from active plate-bounding faults. Here we report results from a borehole drilled into the upper part of the Alpine Fault, which is late in its cycle of stress accumulation and expected to rupture in a magnitude 8 earthquake in the coming decades. The borehole (depth 893 metres) revealed a pore fluid pressure gradient exceeding 9 ± 1 per cent above hydrostatic levels and an average geothermal gradient of 125 ± 55 degrees Celsius per kilometre within the hanging wall of the fault. These extreme hydrothermal conditions result from rapid fault movement, which transports rock and heat from depth, and topographically driven fluid movement that concentrates heat into valleys. Shear heating may occur within the fault but is not required to explain our observations. Our data and models show that highly anomalous fluid pressure and temperature gradients in the upper part of the seismogenic zone can be created by positive feedbacks between processes of fault slip, rock fracturing and alteration, and landscape development at plate-bounding faults.

  17. Extreme wind conditions for a Danish offshore site

    DEFF Research Database (Denmark)

    Hansen, Kurt S.

    2000-01-01

    This paper presents an analysis of extreme wind speed gust values measured at a shallow water offshore site and at a coastal onshore site in Denmark. An estimate of 50-year extreme values has been evaluated using a new statistical method. In addition a mean gust shape is determined, based on a la...

  18. Extreme Conditioning Programs: Potential Benefits and Potential Risks.

    Science.gov (United States)

    Knapik, Joseph J

    2015-01-01

    CrossFit, Insanity, Gym Jones, and P90X are examples of extreme conditioning programs (ECPs). ECPs typically involve high-volume and high-intensity physical activities with short rest periods between movements and use of multiple joint exercises. Data on changes in fitness with ECPs are limited to CrossFit investigations that demonstrated improvements in muscle strength, muscular endurance, aerobic fitness, and body composition. However, no study has directly compared CrossFit or other ECPs to other more traditional forms of aerobic and resistance training within the same investigation. These direct comparisons are needed to more adequately evaluate the effectiveness of ECPs. Until these studies emerge, the comparisons with available literature suggest that improvements in CrossFit, in terms of muscular endurance (push-ups, sit-ups), strength, and aerobic capacity, appear to be similar to those seen in more traditional training programs. Investigations of injuries in ECPs are limited to two observational studies that suggest that the overall injury rate is similar to that seen in other exercise programs. Several cases of rhabdomyolysis and cervical carotid artery dissections have been reported during CrossFit training. The symptoms, diagnosis, and treatment of these are reviewed here. Until more data on ECPs emerge, physical training should be aligned with US Army doctrine. If ECPs are included in exercise programs, trainers should (1) have appropriate training certifications, (2) inspect exercise equipment regularly to assure safety, (3) introduce ECPs to new participants, (4) ensure medical clearance of Soldiers with special health problems before participation in ECPs, (4) tailor ECPs to the individual Soldier, (5) adjust rest periods to optimize recovery and reduce fatigue, (6) monitor Soldiers for signs of overtraining, rhabdomyolysis, and other problems, and (7) coordinate exercise programs with other unit training activities to eliminate redundant activities

  19. Final Report for Project. Quark matter under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Incera, Vivian [Univ. of Texas, El Paso, TX (United States); Ferrer, Efrain [Univ. of Texas, El Paso, TX (United States)

    2015-12-31

    The results obtained in the two years of the grant have served to shine new light on several important questions about the phases of quantum chromodynamics (QCD) under extreme conditions that include quark matter at high density, as well quark-gluon plasma at high temperatures, both in the presence of strong magnetic fields. The interest in including an external magnetic field on these studies is motivated by the generation of large magnetic fields in off-central heavy-ion collisions and by their common presence in astrophysical compact objects, the two scenarios where the physics of quark matter becomes relevant. The tasks carried out in this DOE project led us, among other things, to discover the first connection between the physics of very dense quark matter and novel materials as for instance topological insulators and Weyl semimetals; they allowed us to find a physical explanation for and a solution to a standing puzzle in the apparent effect of a magnetic field on the critical temperature of the QCD chiral transition; and they led us to establish by the first time that the core of the observed two-solar-mass neutron stars could be made up of quark matter in certain inhomogeneous chiral phases in a magnetic field and that this was consistent with current astrophysical observations. A major goal established by the Nuclear Science Advisory committee in its most recent report “Reaching for the Horizon” has been “to truly understand how nuclei and strongly interacting matter in all its forms behave and can predict their behavior in new settings.” The results found in this DOE project have all contributed to address this goal, and thus they are important for advancing fundamental knowledge in the area of nuclear physics and for enhancing our understanding of the role of strong magnetic fields in the two settings where they are most relevant, neutron stars and heavy-ion collisions.

  20. Final Report for Project. Quark matter under extreme conditions

    International Nuclear Information System (INIS)

    Incera, Vivian; Ferrer, Efrain

    2015-01-01

    The results obtained in the two years of the grant have served to shine new light on several important questions about the phases of quantum chromodynamics (QCD) under extreme conditions that include quark matter at high density, as well quark-gluon plasma at high temperatures, both in the presence of strong magnetic fields. The interest in including an external magnetic field on these studies is motivated by the generation of large magnetic fields in off-central heavy-ion collisions and by their common presence in astrophysical compact objects, the two scenarios where the physics of quark matter becomes relevant. The tasks carried out in this DOE project led us, among other things, to discover the first connection between the physics of very dense quark matter and novel materials as for instance topological insulators and Weyl semimetals; they allowed us to find a physical explanation for and a solution to a standing puzzle in the apparent effect of a magnetic field on the critical temperature of the QCD chiral transition; and they led us to establish by the first time that the core of the observed two-solar-mass neutron stars could be made up of quark matter in certain inhomogeneous chiral phases in a magnetic field and that this was consistent with current astrophysical observations. A major goal established by the Nuclear Science Advisory committee in its most recent report 'Reaching for the Horizon' has been 'to truly understand how nuclei and strongly interacting matter in all its forms behave and can predict their behavior in new settings.' The results found in this DOE project have all contributed to address this goal, and thus they are important for advancing fundamental knowledge in the area of nuclear physics and for enhancing our understanding of the role of strong magnetic fields in the two settings where they are most relevant, neutron stars and heavy-ion collisions.

  1. Directional analysis of extreme winds under mixed climate conditions

    CSIR Research Space (South Africa)

    Kruger, A

    2013-07-01

    Full Text Available Directional statistics provide design engineers with the opportunity to realise considerable cost savings, but these are not yet provided for in the South African standard for wind loading. The development of the directional statistics of extreme...

  2. Near-extreme system condition and near-extreme remaining useful time for a group of products

    International Nuclear Information System (INIS)

    Wang, Hai-Kun; Li, Yan-Feng; Huang, Hong-Zhong; Jin, Tongdan

    2017-01-01

    When a group of identical products is operating in field, the aggregation of failures is a catastrophe to engineers and customers who strive to develop reliable and safe products. In order to avoid a swarm of failures in a short time, it is essential to measure the degree of dispersion from different failure times in a group of products to the first failure time. This phenomenon is relevant to the crowding of system conditions near the worst one among a group of products. The group size in this paper represents a finite number of products, instead of infinite number or a single product. We evaluate the reliability of the product fleet from two aspects. First, we define near-extreme system condition and near-extreme failure time for offline solutions, which means no online observations. Second, we apply them to a continuous degradation system that breaks down when it reaches a soft failure threshold. By using particle filtering in the framework of prognostics and health management for a group of products, we aim to estimate near-extreme system condition and further predict the remaining useful life (RUL) using online solutions. Numerical examples are provided to demonstrate the effectiveness of the proposed method. - Highlights: • The aggregation of failures is measured for a group of identical products. • The crowding of failures is quantitated by the near-extreme evaluations. • Near-extreme system condition are given for offline solutions. • Near-extreme remaining useful time are provided for online solutions.

  3. Matter in Extreme Conditions Instrument - Conceptual Design Report

    Energy Technology Data Exchange (ETDEWEB)

    Boyce, R.F.; Boyce, R.M.; Haller, G.; Hastings, J.B.; Hays, G.; Lee, H.J.; /SLAC; Lee, R.W.; /LLNL, Livermore; Nagler, B.; /Rutherford; Scharfenstein, M.; Marsh, D.; White, W.E.; /SLAC

    2009-12-09

    The SLAC National Accelerator Laboratory (SLAC), in collaboration with Argonne National Laboratory (ANL), Lawrence Livermore National Laboratory (LLNL), and the University of California at Los Angeles (UCLA), is constructing a Free-Electron Laser (FEL) research facility. The FEL has already met its performance goals in the wavelength range 1.5 nm - 0.15 nm. This facility, the Linac Coherent Light Source (LCLS), utilizes the SLAC 2-Mile Linear Accelerator (linac) and will produce sub-picosecond pulses of short wavelength X-rays with very high peak brightness and almost complete transverse coherence. The final one-third of the SLAC linac is used as the source of electrons for the LCLS. The high energy electrons are transported across the SLAC Research Yard, into a tunnel which houses a long undulator. In passing through the undulator, the electrons are bunched by the force of their own synchrotron radiation and produce an intense, monochromatic, spatially coherent beam of X-rays. By varying the electron energy, the FEL X-ray wavelength is tunable from 1.5 nm to 0.15 nm. The LCLS includes two experimental halls as well as X-ray optics and infrastructure necessary to create a facility that can be developed for research in a variety of disciplines such as atomic physics, materials science, plasma physics and biosciences. This Conceptual Design Report, the authors believe, confirms the feasibility of designing and constructing an X-ray instrument in order to exploit the unique scientific capability of LCLS by creating extreme conditions and study the behavior of plasma under those controlled conditions. This instrument will address the Office of Science, Fusion Energy Sciences, mission objective related to study of Plasma and Warm Dense Matter as described in the report titled LCLS, the First Experiments, prepared by the LCLS Scientific Advisory Committee (SAC) in September 2000. The technical objective of the LCLS Matter in Extreme Conditions (MEC) Instrument project is

  4. Degradation of textile dyes using immobilized lignin peroxidase-like metalloporphines under mild experimental conditions

    Directory of Open Access Journals (Sweden)

    Zucca Paolo

    2012-12-01

    Full Text Available Abstract Background Synthetic dyes represent a broad and heterogeneous class of durable pollutants, that are released in large amounts by the textile industry. The ability of two immobilized metalloporphines (structurally emulating the ligninolytic peroxidases to bleach six chosen dyes (alizarin red S, phenosafranine, xylenol orange, methylene blue, methyl green, and methyl orange was compared to enzymatic catalysts. To achieve a green and sustainable process, very mild conditions were chosen. Results IPS/MnTSPP was the most promising biomimetic catalyst as it was able to effectively and quickly bleach all tested dyes. Biomimetic catalysis was fully characterized: maximum activity was centered at neutral pH, in the absence of any organic solvent, using hydrogen peroxide as the oxidant. The immobilized metalloporphine kept a large part of its activity during multi-cycle use; however, well-known redox mediators were not able to increase its catalytic activity. IPS/MnTSPP was also more promising for use in industrial applications than its enzymatic counterparts (lignin peroxidase, laccase, manganese peroxidase, and horseradish peroxidase. Conclusions On the whole, the conditions were very mild (standard pressure, room temperature and neutral pH, using no organic solvents, and the most environmental-friendly oxidant and a significant bleaching and partial mineralization of the dyes was achieved in approximately 1 h. Therefore, the process was consistent with large-scale applications. The biomimetic catalyst also had more promising features than the enzymatic catalysts.

  5. Biological effects of extreme environmental conditions. [considering limits of biosphere

    Science.gov (United States)

    Imshenetskiy, A. A.

    1975-01-01

    Actions of extreme physical and chemical space factors on microorganisms and plants are elaborated in order to establish limits for the biosphere. Considered are effects of low and high temperatures; ionizing and ultraviolet radiation; various gases; and effects of vibration, desiccation and acceleration.

  6. An Efficient Synthesis of Nitriles from Aldoximes Using Diethyl Phosphorocyanidate under Mild Conditions

    International Nuclear Information System (INIS)

    Lee, Kieseung; An, Hyeonseong; Hwang, Chanyeon

    2012-01-01

    Nitriles are valuable intermediates in organic synthesis not only because they serve as the appropriate precursors to various functional groups, but also because they are widely used as the key intermediates for pharmaceuticals, agrochemicals and various N-heterocyclic compounds. The cyano group itself is also frequently found in many biologically important molecules. Therefore, a variety of synthetic routes to nitriles from diverse chemical precursors have been developed. Among these routes, nitrile synthesis from aldoximes using an appropriate dehydrating agent has been a general and clean method. For this purpose, numerous reagents such as chlorosulfonyl isocyanate, di-2-pyridyl sulfite, Burgess reagent, [RuCl 2 (p-cymene)] 2 /MS, 4A, BOP, Pd(OAc) 2 /PPh 3 , Cu(OAc) 2 /ultrasound have been developed. These reagents, however, may have limitations in some respects such as harsh reaction conditions, use of expensive or less readily available reagents, low yields, and lack of generality. Therefore, there is still a need to develop mild and general method for this conversion. Diethyl phosphorocyanidate (DEPC) was initially introduced as an efficient peptide coupling reagent, and has been utilized for useful organic reactions. Previously, we reported that 2-chloro-1-methylpyridinium iodide is an efficient and mild reagent for the dehydration of aldoximes to nitriles under mild conditions. In continuation of our interest in developing mild method for the conversion of aldoximes to nitriles, we herein wish to report the first application of DEPC to the efficient synthesis of nitriles from aldoximes under mild conditions (Scheme 1). In order to obtain the information regarding the optimum reaction conditions, 4-pyridine aldoxime (1a) was reacted with DEPC without base, and in presence of various base in CH 2 Cl 2 at rt for a prolonged reaction time (20 h) (Table 1). CH 2 CI 2 was chosen as reaction medium in this reaction due to the good solubility for both 1 and 3 in CH

  7. An Efficient Synthesis of Nitriles from Aldoximes Using Diethyl Phosphorocyanidate under Mild Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kieseung; An, Hyeonseong; Hwang, Chanyeon [Woosuk Univ.,Wanju (Korea, Republic of)

    2012-10-15

    Nitriles are valuable intermediates in organic synthesis not only because they serve as the appropriate precursors to various functional groups, but also because they are widely used as the key intermediates for pharmaceuticals, agrochemicals and various N-heterocyclic compounds. The cyano group itself is also frequently found in many biologically important molecules. Therefore, a variety of synthetic routes to nitriles from diverse chemical precursors have been developed. Among these routes, nitrile synthesis from aldoximes using an appropriate dehydrating agent has been a general and clean method. For this purpose, numerous reagents such as chlorosulfonyl isocyanate, di-2-pyridyl sulfite, Burgess reagent, [RuCl{sub 2}(p-cymene)]{sub 2}/MS, 4A, BOP, Pd(OAc){sub 2}/PPh{sub 3}, Cu(OAc){sub 2}/ultrasound have been developed. These reagents, however, may have limitations in some respects such as harsh reaction conditions, use of expensive or less readily available reagents, low yields, and lack of generality. Therefore, there is still a need to develop mild and general method for this conversion. Diethyl phosphorocyanidate (DEPC) was initially introduced as an efficient peptide coupling reagent, and has been utilized for useful organic reactions. Previously, we reported that 2-chloro-1-methylpyridinium iodide is an efficient and mild reagent for the dehydration of aldoximes to nitriles under mild conditions. In continuation of our interest in developing mild method for the conversion of aldoximes to nitriles, we herein wish to report the first application of DEPC to the efficient synthesis of nitriles from aldoximes under mild conditions (Scheme 1). In order to obtain the information regarding the optimum reaction conditions, 4-pyridine aldoxime (1a) was reacted with DEPC without base, and in presence of various base in CH{sub 2}Cl{sub 2} at rt for a prolonged reaction time (20 h) (Table 1). CH{sub 2}CI{sub 2} was chosen as reaction medium in this reaction due to the

  8. Pretreatment combining ultrasound and sodium percarbonate under mild conditions for efficient degradation of corn stover.

    Science.gov (United States)

    Nakashima, Kazunori; Ebi, Yuuki; Kubo, Masaki; Shibasaki-Kitakawa, Naomi; Yonemoto, Toshikuni

    2016-03-01

    Ultrasound (US) can be used to disrupt microcrystalline cellulose to give nanofibers via ultrasonic cavitation. Sodium percarbonate (SP), consisting of sodium carbonate and hydrogen peroxide, generates highly reactive radicals, which cause oxidative delignification. Here, we describe a novel pretreatment technique using a combination of US and SP (US-SP) for the efficient saccharification of cellulose and hemicellulose in lignocellulosic corn stover. Although US-SP pretreatment was conducted under mild condition (i.e., at room temperature and atmospheric pressure), the pretreatment greatly increased lignin removal and cellulose digestibility. We also determined the optimum US-SP treatment conditions, such as ultrasonic power output, pretreatment time, pretreatment temperature, and SP concentration for an efficient cellulose saccharification. Moreover, xylose could be effectively recovered from US-SP pretreated biomass without the formation of microbial inhibitor furfural. Copyright © 2015 Elsevier B.V. All rights reserved.

  9. Transition-Metal-Free Highly Efficient Aerobic Oxidation of Sulfides to Sulfoxides under Mild Conditions

    Directory of Open Access Journals (Sweden)

    Hua Zhang

    2009-12-01

    Full Text Available A highly efficient transition-metal-free catalytic system Br2/NaNO2/H2O has been developed for a robust and economic acid-free aerobic oxidation of sulfides. It is noteworthy that the sulfide function reacts under mild conditions without over-oxidation to sulfone. The role of NaNO2as an efficient NO equivalent for the activation of molecular oxygen was identified. Under the optimal conditions, a broad range of sulfide substrates were converted into their corresponding sulfoxides in high yields by molecular oxygen. The present catalytic system utilizes cheap and readily available agents as the catalysts, exhibits high selectivity for sulfoxide products and releases only innocuous water as the by-products.

  10. Rational Calibration of Four IEC 61400-1 Extreme External Conditions

    DEFF Research Database (Denmark)

    Larsen, Gunner Chr.; Hansen, Kurt Schaldemose

    2008-01-01

    Based on a set of asymptotic statistical models on closed form this paper presents a rational and consistent calibration of four extreme external conditions defined in the International Electrotechnical Commission (IEC) 61400-1 standard: extreme operating gust, extreme wind shear, extreme coheren...... and proposed specifications of the magnitudes of the extreme external wind conditions are highlighted and discussed using an illustrative example based on two selected terrain types. Copyright © 2008 John Wiley & Sons, Ltd....... gust with direction change and extreme wind direction change. These four extreme external conditions are used in the definition of six of the IEC 61400-1 ultimate load cases. The statistical models are based on simple and easily accessible mean wind speed and turbulence characteristics...

  11. Effect of hydrogen on hydrogen-methane turbulent non-premixed flame under MILD condition

    Energy Technology Data Exchange (ETDEWEB)

    Mardani, Amir; Tabejamaat, Sadegh [Department of Aerospace engineering, Amirkabir university of technology (Tehran polytechnic), Hafez Ave., PO. Box: 15875-4413, Tehran (Iran)

    2010-10-15

    Energy crises and the preservation of the global environment are placed man in a dilemma. To deal with these problems, finding new sources of fuel and developing efficient and environmentally friendly energy utilization technologies are essential. Hydrogen containing fuels and combustion under condition of the moderate or intense low-oxygen dilution (MILD) are good choices to replace the traditional ones. In this numerical study, the turbulent non-premixed CH{sub 4}+H{sub 2} jet flame issuing into a hot and diluted co-flow air is considered to emulate the combustion of hydrogen containing fuels under MILD conditions. This flame is related to the experimental condition of Dally et al. [Proc. Combust. Inst. 29 (2002) 1147-1154]. In general, the modelling is carried out using the EDC model, to describe turbulence-chemistry interaction, and the DRM-22 reduced mechanism and the GRI2.11 full mechanism to represent the chemical reactions of H{sub 2}/methane jet flame. The effect of hydrogen content of fuel on flame structure for two co-flow oxygen levels is studied by considering three fuel mixtures, 5%H{sub 2}+95%CH{sub 4}, 10%H{sub 2}+90%CH{sub 4} and 20% H{sub 2}+80%CH{sub 4}(by mass). In this study, distribution of species concentrations, mixture fraction, strain rate, flame entrainment, turbulent kinetic energy decay and temperature are investigated. Results show that the hydrogen addition to methane leads to improve mixing, increase in turbulent kinetic energy decay along the flame axis, increase in flame entrainment, higher reaction intensities and increase in mixture ignitability and rate of heat release. (author)

  12. Stable pelagic vertebrate community structure through extreme Paleogene greenhouse conditions

    Science.gov (United States)

    Sibert, E. C.; Friedman, M.; Hull, P. M.; Hunt, G.; Norris, R. D.

    2016-02-01

    The species composition (structure) and energy transfer (function) of an ecosystem is reflected by the presence and type of consumers that it supports. Here we use ichthyoliths, microfossil fish teeth and shark denticles, to assess the ecological variability of the pelagic fish community structure and composition from the Late Cretaceous to the middle Eocene from a drill core in the South Pacific gyre (DSDP Site 596). We find that the overall vertebrate community structure, as measured by the relative abundance of sharks to ray-finned fishes, has a punctuated change at the Cretaceous/Paleogene mass extinction. The vertebrate community structure remained stable throughout the Paleogene despite a five-fold increase in overall abundance of ichthyoliths during the extreme greenhouse of the Early Eocene. Further, we use a novel system to quantify the morphological variation in fish teeth. We find that the morphospace occupied by the tooth assemblage is conserved throughout the interval, with a slight expansion following the Cretaceous-Paleogene mass extinction, and the evolution of a distinct morphotype-group around the Paleocene-Eocene boundary. While there are elevated rates of morphotype origination and extinction following the Cretaceous-Paleogene mass extinction, the extreme greenhouse warming of the Early Eocene and associated increase in fish production produce near-zero origination and extinction rates. The relative stability in composition of the pelagic vertebrate community during intervals of extreme climate change and across large ranges of total fish accumulation, suggests that pelagic ecosystem structure is robust to climate events, and that the overall structure of the pelagic fish community may be decoupled from both climate and ecosystem function.

  13. Condensed Matter NMR under Extreme Conditions: Challenges and Opportunities

    Science.gov (United States)

    Reyes, Arneil

    2006-11-01

    Advances in resistive magnet and power supply technology have made available extremely high magnetic fields suitable for condensed matter broadline NMR experiments. This capability expands the available phase space for investigating a wide variety of materials using magnetic resonance; utilizing the strength of the field to expose or induce new physical phenomena resulting in better understanding of the physics. Continuous fields up to 45T in NHMFL Hybrid magnet have brought new challenges in designing NMR instrumentation. Field strengths and sample space limitations put constraints on RF pulse power, tuning range, bandwidth, and temperature control. The inclusion of other capabilities, including high pressure, optics, and sample rotation requires intricate probe design and construction, while extremely low milliKelvin temperatures are desired in order to explore energy scales where thermal fluctuations are suppressed. Optimization of these devices has been of paramount consideration in NHMFL Condensed Matter NMR user program. Science achieved at high fields, the new initiatives to develop resistively-detected NMR in 2D electron gas and similar systems, and the current new generation Series-Connected Hybrid magnets for NMR work will be discussed. The NHMFL is supported by the National Science Foundation and the State of Florida.

  14. Uncertainties in extreme precipitation under climate change conditions

    DEFF Research Database (Denmark)

    Sunyer Pinya, Maria Antonia

    of adaptation strategies, but these changes are subject to uncertainties. The focus of this PhD thesis is the quantification of uncertainties in changes in extreme precipitation. It addresses two of the main sources of uncertainty in climate change impact studies: regional climate models (RCMs) and statistical...... downscaling methods (SDMs). RCMs provide information on climate change at the regional scale. SDMs are used to bias-correct and downscale the outputs of the RCMs to the local scale of interest in adaptation strategies. In the first part of the study, a multi-model ensemble of RCMs from the European ENSEMBLES...... project was used to quantify the uncertainty in RCM projections over Denmark. Three aspects of the RCMs relevant for the uncertainty quantification were first identified and investigated. These are: the interdependency of the RCMs; the performance in current climate; and the change in the performance...

  15. A Novel Glycinate-based Body Wash: Clinical Investigation Into Ultra-mildness, Effective Conditioning, and Improved Consumer Benefits.

    Science.gov (United States)

    Regan, Jamie; Mollica, Leonel-Maximo; Ananthapadmanabhan, K P

    2013-06-01

    To assess the properties of a novel body wash containing the mild surfactant glycinate. Biochemical and clinical assays. Research laboratories and clinical sites in the United States and Canada. Women 18 to 65 years of age (cleansing efficacy); male and female subjects 26 to 63 years of age with mild or moderate dryness and erythema (leg-controlled application test); subjects 5 to 65 years of age with mild-to-moderate eczema (eczema compatibility); and women 18 to 64 years of age (home use). Assessments across studies included colorimetric dye exclusion to assess skin damage potential (corneosurfametry), efficacy of cosmetic product removal from skin, change from baseline in visual dryness, change from baseline in Eczema Area and Severity Index, and self-perceived eczema attributes and self-reported product preference. The glycinate-based cleanser demonstrated mildness to skin components when evaluated in a corneosurfametry assay. Short-term use under exaggerated wash conditions in subjects with dryness scores benefits.

  16. 49 CFR 392.14 - Hazardous conditions; extreme caution.

    Science.gov (United States)

    2010-10-01

    ... CARRIER SAFETY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION FEDERAL MOTOR CARRIER SAFETY REGULATIONS DRIVING OF COMMERCIAL MOTOR VEHICLES Driving of Commercial Motor Vehicles § 392.14 Hazardous conditions... nearest point at which the safety of passengers is assured. [33 FR 19732, Dec. 25, 1968, as amended at 60...

  17. Extremal and Degree Conditions for Path Extendability in Digraphs

    NARCIS (Netherlands)

    Zhang, Zan-Bo; Zhang, Xiaoyan; Broersma, Hajo; Lou, Dingjun

    2017-01-01

    In the study of cycles and paths, the meta-conjecture of Bondy that sufficient conditions for Hamiltonicity often imply pancyclicity has motivated research on the existence of cycles and paths of many lengths. Hendry further introduced the stronger concepts of cycle extendability and path

  18. Behavior of whey protein concentrates under extreme storage conditions

    Science.gov (United States)

    The overseas demand for whey protein concentrates (WPC) has increased steadily in recent years. Emergency aid foods often include WPC, but shelf-life studies of whey proteins under different shipment and storage conditions have not been conducted in the last 50 yr. Microbial quality, compound form...

  19. Extreme hydrothermal conditions at an active plate-bounding fault

    NARCIS (Netherlands)

    Sutherland, Rupert; Townend, John; Toy, Virginia; Upton, Phaedra; Coussens, Jamie; Allen, Michael; Baratin, Laura May; Barth, Nicolas; Becroft, Leeza; Boese, Carolin; Boles, Austin; Boulton, Carolyn; Broderick, Neil G.R.; Janku-Capova, Lucie; Carpenter, Brett M.; Célérier, Bernard; Chamberlain, Calum; Cooper, Alan; Coutts, Ashley; Cox, Simon; Craw, Lisa; Doan, Mai Linh; Eccles, Jennifer; Faulkner, Dan; Grieve, Jason; Grochowski, Julia; Gulley, Anton; Hartog, Arthur; Howarth, Jamie; Jacobs, Katrina; Jeppson, Tamara; Kato, Naoki; Keys, Steven; Kirilova, Martina; Kometani, Yusuke; Langridge, Rob; Lin, Weiren; Little, Timothy; Lukacs, Adrienn; Mallyon, Deirdre; Mariani, Elisabetta; Massiot, Cécile; Mathewson, Loren; Melosh, Ben; Menzies, Catriona; Moore, Jo; Morales, Luiz; Morgan, Chance; Mori, Hiroshi; Niemeijer, Andre|info:eu-repo/dai/nl/370832132; Nishikawa, Osamu; Prior, David; Sauer, Katrina; Savage, Martha; Schleicher, Anja; Schmitt, Douglas R.; Shigematsu, Norio; Taylor-Offord, Sam; Teagle, Damon; Tobin, Harold; Valdez, Robert; Weaver, Konrad; Wiersberg, Thomas; Williams, Jack; Woodman, Nick; Zimmer, Martin

    2017-01-01

    Temperature and fluid pressure conditions control rock deformation and mineralization on geological faults, and hence the distribution of earthquakes. Typical intraplate continental crust has hydrostatic fluid pressure and a near-surface thermal gradient of 31 ± 15 degrees Celsius per kilometre. At

  20. Performance of Chlorella sorokiniana under simulated extreme winter conditions

    NARCIS (Netherlands)

    Cuaresma, M.; Buffing, M.F.; Janssen, M.G.J.; Lobato, C.V.; Wijffels, R.H.

    2012-01-01

    High annual microalgae productivities can only be achieved if solar light is efficiently used through the different seasons. During winter the productivity is low because of the light and temperature conditions. The productivity and photosynthetic efficiency of Chlorella sorokiniana were assessed

  1. Fast Curing Bio-Based Phenolic Resins via Lignin Demethylated under Mild Reaction Condition

    Directory of Open Access Journals (Sweden)

    Jiongjiong Li

    2017-09-01

    Full Text Available Demethylation technique has been used to enhance lignin reactivity for preparation of phenolic resins. However, the demethylation efficiency and the demethylated lignin (DL reactivity were still unsatisfactory. To improve the demethylation efficiency, alkali lignin was demethylated under different mild conditions using sodium sulfite as a catalyst. Lignin and DL were characterized by 1H-NMR (nuclear magnetic resonance and Fourier transform infrared (FT-IR spectroscopy to determine the demethylation mechanism. With the demethylation of lignin, the methoxyl group content decreased from 1.93 m mol/g to 1.09 m mol/g, and the phenolic hydroxyl group content increased from 0.56 m mol/g to 0.82 m mol/g. These results revealed that methoxyl groups were attacked by SO32−, and some methoxyl groups were converted to phenolic hydroxyl groups by a nucleophilic substitution reaction, generating DL with high reactivity. The chemical properties of lignin-based phenolic resins were studied by 13C-NMR and FT-IR spectroscopy, and their physical properties were also investigated. The results indicated that lignin-based phenolic resins exhibited faster curing rate and shorter gel time. In addition, the bonding strength increased from 0.92 MPa to 1.07 MPa, and the formaldehyde emission decreased from 0.58 mg/L to 0.22 mg/L after lignin demethylated at the optimum condition.

  2. Mathematical modelling of unglazed solar collectors under extreme operating conditions

    DEFF Research Database (Denmark)

    Bunea, M.; Perers, Bengt; Eicher, S.

    2015-01-01

    average temperature levels at the evaporator. Simulation of these systems requires a collector model that can take into account operation at very low temperatures (below freezing) and under various weather conditions, particularly operation without solar irradiation.A solar collector mathematical model......Combined heat pumps and solar collectors got a renewed interest on the heating system market worldwide. Connected to the heat pump evaporator, unglazed solar collectors can considerably increase their efficiency, but they also raise the coefficient of performance of the heat pump with higher...... was found due to the condensation phenomenon and up to 40% due to frost under no solar irradiation. This work also points out the influence of the operating conditions on the collector's characteristics.Based on experiments carried out at a test facility, every heat flux on the absorber was separately...

  3. TRISO-Coated Fuel Durability Under Extreme Conditions

    International Nuclear Information System (INIS)

    2014-01-01

    The PIs propose to examine TRISO-coated particles (SiC and ZrC coatings) in an integrated two-part study. In the first part, experiments will be performed to assess the reaction kinetics of the carbides under CO-CO2 environments at temperatures up to 1800 degree C. Kinetic model will be applied to describe the degradation. Scanning and transmission electron microscopy will be employed to establish the chemical and microstructure evolution under the imposed environmental conditions. The second part of the proposed work focuses on establishing the role of the high temperature, environmental exposure described above on the mechanical behavior of TRISO-coated particles. Electron microscopy and other advanced techniques will be subsequently performed to evaluate failure mechanisms. The work is expected to reveal relationships between corrosion reactions, starting material characteristics (polytype of SiC, impurity concentration, flaw distribution), flaw healing behavior, and crack growth.

  4. The Sphagnum microbiome supports bog ecosystem functioning under extreme conditions.

    Science.gov (United States)

    Bragina, Anastasia; Oberauner-Wappis, Lisa; Zachow, Christin; Halwachs, Bettina; Thallinger, Gerhard G; Müller, Henry; Berg, Gabriele

    2014-09-01

    Sphagnum-dominated bogs represent a unique yet widely distributed type of terrestrial ecosystem and strongly contribute to global biosphere functioning. Sphagnum is colonized by highly diverse microbial communities, but less is known about their function. We identified a high functional diversity within the Sphagnum microbiome applying an Illumina-based metagenomic approach followed by de novo assembly and MG-RAST annotation. An interenvironmental comparison revealed that the Sphagnum microbiome harbours specific genetic features that distinguish it significantly from microbiomes of higher plants and peat soils. The differential traits especially support ecosystem functioning by a symbiotic lifestyle under poikilohydric and ombrotrophic conditions. To realise a plasticity-stability balance, we found abundant subsystems responsible to cope with oxidative and drought stresses, to exchange (mobile) genetic elements, and genes that encode for resistance to detrimental environmental factors, repair and self-controlling mechanisms. Multiple microbe-microbe and plant-microbe interactions were also found to play a crucial role as indicated by diverse genes necessary for biofilm formation, interaction via quorum sensing and nutrient exchange. A high proportion of genes involved in nitrogen cycle and recycling of organic material supported the role of bacteria for nutrient supply. 16S rDNA analysis indicated a higher structural diversity than that which had been previously detected using PCR-dependent techniques. Altogether, the diverse Sphagnum microbiome has the ability to support the life of the host plant and the entire ecosystem under changing environmental conditions. Beyond this, the moss microbiome presents a promising bio-resource for environmental biotechnology - with respect to novel enzymes or stress-protecting bacteria. © 2014 John Wiley & Sons Ltd.

  5. Beryllium armoured target for extreme heat and neutron loading conditions

    International Nuclear Information System (INIS)

    Mazul, I.; Gervash, A.; Giniyatulin, R.

    2004-01-01

    Beryllium is a primary candidate as a target material for high-energy protons conversion into neutrons used for different applications. In order to get higher neutron flux the conversion area has to be minimized - in our case the target is limited by 1-2 liter volume. This target generates about 5·10 13 fast neutrons per second and removes of 150 kW thermal power deposited by proton beam (30 mA, 5 MeV), coming from linac. The operational condition of the converter is close to the condition of Be-armored components in fusion reactors: high thermal and neutron fluxes and active cooling. Therefore achievements in development of water-cooled high heat flux components for fusion application can be used for design of Be converter and vice versa. However for medical application the using of high-activated heat sink materials such as Cu and SS is strongly limited. So, new materials (Be, Al, Zr) and new joining technologies in comparison with the achievements in fusion area have to be used for construction of such Be converter. In order to reduce amount of heat sink materials in the target saddle-block geometry for Be armor is suggested and developed. Results of R and D works on the development of water cooled Be target for converter are presented, including data on selected materials, technological trials and mockups high heat flux testing. Preliminary design of Be neutron converter for medical applications based on R and D results is presented. (author)

  6. Enzymatic formulation capable of degrading scrapie prion under mild digestion conditions.

    Directory of Open Access Journals (Sweden)

    Emeka A Okoroma

    Full Text Available The prion agent is notoriously resistant to common proteases and conventional sterilisation procedures. The current methods known to destroy prion infectivity such as incineration, alkaline and thermal hydrolysis are harsh, destructive, environmentally polluting and potentially hazardous, thus limit their applications for decontamination of delicate medical and laboratory devices, remediation of prion contaminated environment and for processing animal by-products including specified risk materials and carcases. Therefore, an environmentally friendly, non-destructive enzymatic degradation approach is highly desirable. A feather-degrading Bacillus licheniformis N22 keratinase has been isolated which degraded scrapie prion to undetectable level of PrP(Sc signals as determined by Western Blot analysis. Prion infectivity was verified by ex vivo cell-based assay. An enzymatic formulation combining N22 keratinase and biosurfactant derived from Pseudomonas aeruginosa degraded PrP(Sc at 65 °C in 10 min to undetectable level -. A time-course degradation analysis carried out at 50 °C over 2 h revealed the progressive attenuation of PrP(Sc intensity. Test of residual infectivity by standard cell culture assay confirmed that the enzymatic formulation reduced PrP(Sc infectivity to undetectable levels as compared to cells challenged with untreated standard scrapie sheep prion (SSBP/1 (p-value = 0.008 at 95% confidence interval. This novel enzymatic formulation has significant potential application for prion decontamination in various environmentally friendly systems under mild treatment conditions.

  7. The photochemical reaction of hydrocarbons under extreme thermobaric conditions

    Science.gov (United States)

    Serovaiskii, Aleksandr; Kolesnikov, Anton; Mukhina, Elena; Kutcherov, Vladimir

    2017-10-01

    The photochemical reaction of hydrocarbons was found to play an important role in the experiments with the synthetic petroleum conducted in Diamond Anvil Cell (DAC). Raman spectroscopy with a green laser (514.5 nm) was used for in situ sample analysis. This photochemical effect was investigated in the pressure range of 0.7-5 GPa, in the temperature interval from the ambient conditions to 450°C. The power of laser used in these experiment series was from 0.05 W to 0.6 W. The chemical transformation was observed when the necessary threshold pressure (~2.8 GPa) was reached. This transformation correlated with the luminescence appearance on the Raman spectra and a black opaque spot in the sample was observed in the place where the laser focus was forwarded. The exposure time and laser power (at least in the 0.1-0.5 W range) did not play a role in the 0.1-0.5 GPa range.

  8. Study of the pluronic-silica interaction in synthesis of mesoporous silica under mild acidic conditions.

    Science.gov (United States)

    Sundblom, Andreas; Palmqvist, Anders E C; Holmberg, Krister

    2010-02-02

    The interaction between silica and poly(ethylene oxide) (PEO) in water may appear trivial and it is generally stated that hydrogen bonding is responsible for the attraction. However, a literature search shows that there is not a consensus with respect to the mechanism behind the attractive interaction. Several papers claim that only hydrogen bonding is not sufficient to explain the binding. The silica-PEO interaction is interesting from an academic perspective and it is also exploited in the preparation of mesoporous silica, a material of considerable current interest. This study concerns the very early stage of synthesis of mesoporous silica under mild acidic conditions, pH 2-5, and the aim is to shed light on the interaction between silica and the PEO-containing structure directing agent. The synthesis comprises two steps. An organic silica source, tetraethylorthosilicate (TEOS), is first hydrolyzed and Pluronic P123, a poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO) block copolymer, is subsequently added at different time periods following the hydrolysis of TEOS. It is shown that the interaction between the silica and the Pluronic is dependent both on the temperature and on the time between onset of TEOS hydrolysis and addition of the copolymer. The results show that the interaction is mainly driven by entropy. The effect of the synthesis temperature and of the time between hydrolysis and addition of the copolymer on the final material is also studied. The material with the highest degree of mesoorder was obtained when the reaction was performed at 20 degrees C and the copolymer was added 40 h after the start of TEOS hydrolysis. It is claimed that the reason for the good ordering of the silica is that whereas particle formation under these conditions is fast, the rate of silica condensation is relatively low.

  9. Control of Lower Extremity Edema in Patients with Diabetes: Double Blind Randomized Controlled Trial Assessing the Efficacy of Mild Compression Diabetic Socks

    Science.gov (United States)

    Wu, Stephanie C.; Crews, Ryan T.; Skratsky, Melissa; Overstreet, Julia; Yalla, Sai V.; Winder, Michelle; Ortiz, Jacquelyn; Andersen, Charles A.

    2017-01-01

    Aims Persons with diabetes frequently present with lower extremity (LE) edema; however, compression therapy is generally avoided for fear of compromising arterial circulation in a population with a high prevalence of peripheral arterial disease. This double blind randomized controlled trial (RCT) assessed whether diabetic socks with mild compression could reduce LE edema in patients with diabetes without negatively impacting vascularity. Methods Eighty subjects with LE edema and diabetes were randomized to receive either mild-compression knee high diabetic socks (18–25mmHg) or non-compression knee high diabetic socks. Subjects were instructed to wear the socks during all waking hours. Follow-up visits occurred weekly for four consecutive weeks. Edema was quantified through midfoot, ankle, and calf circumferences and cutaneous fluid measurements. Vascular status was tracked via ankle brachial index (ABI), toe brachial index (TBI), and skin perfusion pressure (SPP). Results Seventy-seven subjects (39 controls and 38 mild-compression subjects) successfully completed the study. No statistical differences between the two groups in terms of age, body mass index, gender, and ethnicity. Repeated measures analysis of variance and Sidak corrections for multiple comparisons were used for data analyses. Subjects randomized to mild-compression diabetic socks demonstrated significant decreases in calf and ankle circumferences at the end of treatment as compared to baseline. LE circulation did not diminish throughout the study with no significant decreases in ABI, TBI or SPP for either group. Conclusions Results of this RCT suggest that mild compression diabetic sock may be effectively and safely used in patients with diabetes and LE edema. PMID:28315576

  10. Application of Electro Chemical Machining for materials used in extreme conditions

    Science.gov (United States)

    Pandilov, Z.

    2018-03-01

    Electro-Chemical Machining (ECM) is the generic term for a variety of electrochemical processes. ECM is used to machine work pieces from metal and metal alloys irrespective of their hardness, strength or thermal properties, through the anodic dissolution, in aerospace, automotive, construction, medical equipment, micro-systems and power supply industries. The Electro Chemical Machining is extremely suitable for machining of materials used in extreme conditions. General overview of the Electro-Chemical Machining and its application for different materials used in extreme conditions is presented.

  11. Force Myography for Monitoring Grasping in Individuals with Stroke with Mild to Moderate Upper-Extremity Impairments: A Preliminary Investigation in a Controlled Environment

    Directory of Open Access Journals (Sweden)

    Gautam P. Sadarangani

    2017-07-01

    Full Text Available There is increasing research interest in technologies that can detect grasping, to encourage functional use of the hand as part of daily living, and thus promote upper-extremity motor recovery in individuals with stroke. Force myography (FMG has been shown to be effective for providing biofeedback to improve fine motor function in structured rehabilitation settings, involving isolated repetitions of a single grasp type, elicited at a predictable time, without upper-extremity movements. The use of FMG, with machine learning techniques, to detect and distinguish between grasping and no grasping, continues to be an active area of research, in healthy individuals. The feasibility of classifying FMG for grasp detection in populations with upper-extremity impairments, in the presence of upper-extremity movements, as would be expected in daily living, has yet to be established. We explore the feasibility of FMG for this application by establishing and comparing (1 FMG-based grasp detection accuracy and (2 the amount of training data necessary for accurate grasp classification, in individuals with stroke and healthy individuals. FMG data were collected using a flexible forearm band, embedded with six force-sensitive resistors (FSRs. Eight participants with stroke, with mild to moderate upper-extremity impairments, and eight healthy participants performed 20 repetitions of three tasks that involved reaching, grasping, and moving an object in different planes of movement. A validation sensor was placed on the object to label data as corresponding to a grasp or no grasp. Grasp detection performance was evaluated using linear and non-linear classifiers. The effect of training set size on classification accuracy was also determined. FMG-based grasp detection demonstrated high accuracy of 92.2% (σ = 3.5% for participants with stroke and 96.0% (σ = 1.6% for healthy volunteers using a support vector machine (SVM. The use of a training set that was 50

  12. Numerical Modeling of MILD Combustion at High Pressure to Predict the Optimal Operating Conditions

    KAUST Repository

    Vanteru, Mahendra Reddy; Roberts, William L.

    2017-01-01

    This Chapter presents numerical simulation on MILD combustion operating at high pressure. Influence of preheat and dilution of oxidizer and operating pressure on stabilization of MILD combustion are presented. Three different preheat temperatures (1100, 1300 and 1500 K) and three different dilution levels (3, 6 and 9% O2) are simulated over an operating pressure variation from 1 atm to 16 atm. A classical jet in hot coflow burner is considered for this study. Total of 45 cases are simulated and analyzed. Essential characteristics of MILD combustion, i.e., maximum temperature (Tmax), temperature rise (ΔT) and temperature distributions, are analyzed. The distribution of emissions OH and CO are also studied and presented. Well-stabilized MILD combustion is observed for all cases except for two cases with high preheated (1500 K). Peak temperature is observed to decrease with increasing operating pressure for a given level of preheat and dilution. OH mass faction is reduced with increasing pressure. The CO emissions show little sensitivity to operating pressure. However, CO mass fraction is slightly higher at 1 atm operating pressure as compared to 4 to 16 atm. Since the residence time of reactants increases as the operating pressure increases, well-stabilized MILD combustion is observed for all highly diluted and low temperature preheat cases (3% O2 and 1100 K).

  13. Numerical Modeling of MILD Combustion at High Pressure to Predict the Optimal Operating Conditions

    KAUST Repository

    Vanteru, Mahendra Reddy

    2017-02-01

    This Chapter presents numerical simulation on MILD combustion operating at high pressure. Influence of preheat and dilution of oxidizer and operating pressure on stabilization of MILD combustion are presented. Three different preheat temperatures (1100, 1300 and 1500 K) and three different dilution levels (3, 6 and 9% O2) are simulated over an operating pressure variation from 1 atm to 16 atm. A classical jet in hot coflow burner is considered for this study. Total of 45 cases are simulated and analyzed. Essential characteristics of MILD combustion, i.e., maximum temperature (Tmax), temperature rise (ΔT) and temperature distributions, are analyzed. The distribution of emissions OH and CO are also studied and presented. Well-stabilized MILD combustion is observed for all cases except for two cases with high preheated (1500 K). Peak temperature is observed to decrease with increasing operating pressure for a given level of preheat and dilution. OH mass faction is reduced with increasing pressure. The CO emissions show little sensitivity to operating pressure. However, CO mass fraction is slightly higher at 1 atm operating pressure as compared to 4 to 16 atm. Since the residence time of reactants increases as the operating pressure increases, well-stabilized MILD combustion is observed for all highly diluted and low temperature preheat cases (3% O2 and 1100 K).

  14. Palladium(II-catalyzed Heck reaction of aryl halides and arylboronic acids with olefins under mild conditions

    Directory of Open Access Journals (Sweden)

    Tanveer Mahamadali Shaikh

    2013-08-01

    Full Text Available A series of general and selective Pd(II-catalyzed Heck reactions were investigated under mild reaction conditions. The first protocol has been developed employing an imidazole-based secondary phosphine oxide (SPO ligated palladium complex (6 as a precatalyst. The catalytic coupling of aryl halides and olefins led to the formation of the corresponding coupled products in excellent yields. A variety of substrates, both electron-rich and electron-poor olefins, were converted smoothly to the targeted products in high yields. Compared with the existing approaches employing SPO–Pd complexes in a Heck reaction, the current strategy features mild reaction conditions and broad substrate scope. Furthermore, we described the coupling of arylboronic acids with olefins, which were catalyzed by Pd(OAc2 and employed N-bromosuccinimide as an additive under ambient conditions. The resulted biaryls have been obtained in moderate to good yields.

  15. Mean versus extreme climate in the Mediterranean region and its sensitivity to future global warming conditions

    Energy Technology Data Exchange (ETDEWEB)

    Paeth, H.; Hense, A. [Meteorological Inst., Univ. Bonn (Germany)

    2005-06-01

    The Mediterranean region (MTR) has been supposed to be very sensitive to changes in land surface and atmospheric greenhouse-gas (GHG) concentrations. Particularly, an intensification of climate extremes may be associated with severe socio-economic implications. Here, we present an analysis of climate mean and extreme conditions in this subtropical area based on regional climate model experiments, simulating the present-day and possible future climate. The analysis of extreme values (EVs) is based on the assumption that the extremes of daily precipitation and near-surface temperature are well fitted by the Generalized Pareto distribution (GPD). Return values of extreme daily events are determined using the method of L-moments. Particular emphasis is laid on the evaluation of the return values with respect to the uncertainty range of the estimate as derived from a Monte Carlo sampling approach. During the most recent 25 years the MTR has become dryer in spring but more humid especially in the western part in autumn and winter. At the same time, the whole region has been subject to a substantial warming. The strongest rainfall extremes are simulated in autumn over the Mediterranean Sea around Italy. Temperature extremes are most pronounced over the land masses, especially over northern Africa. Given the large uncertainty of the EV estimate, only 1-year return values are further analysed. During recent decades, statistically significant changes in extremes are only found for temperature. Future climate conditions may come along with a decrease in mean and extreme precipitation during the cold season, whereas an intensification of the hydrological cycle is predicted in summer and autumn. Temperature is predominantly affected over the Iberian Peninsula and the eastern part of the MTR. In many grid boxes, the signals are blurred out due to the large amount of uncertainty in the EV estimate. Thus, a careful analysis is required when making inferences about the future

  16. User-Defined Meteorological (MET) Profiles from Climatological and Extreme Condition Data

    Science.gov (United States)

    2018-04-01

    ARL-TN-0876 ● MAR 2018 US Army Research Laboratory User-Defined Meteorological (MET) Profiles from Climatological and Extreme...needed. Do not return it to the originator. ARL-TN-0876 ● MAR 2018 US Army Research Laboratory User-Defined Meteorological (MET...User-Defined Meteorological (MET) Profiles from Climatological and Extreme Condition Data 5a. CONTRACT NUMBER 5b. GRANT NUMBER 5c. PROGRAM

  17. Mild solutions to a measure-valued mass evolution problem with flux boundary conditions

    NARCIS (Netherlands)

    Evers, J.H.M.; Hille, S.C.; Muntean, A.

    2015-01-01

    We investigate the well-posedness and approximation of mild solutions to a class of linear transport equations on the unit interval [0,1][0,1] endowed with a linear discontinuous production term, formulated in the space M([0,1])M([0,1]) of finite Borel measures. Our working technique includes a

  18. A recessive form of extreme macrocephaly and mild intellectual disability complements the spectrum of PTEN hamartoma tumour syndrome.

    Science.gov (United States)

    Schwerd, Tobias; Khaled, Andrea V; Schürmann, Manfred; Chen, Hannah; Händel, Norman; Reis, André; Gillessen-Kaesbach, Gabriele; Uhlig, Holm H; Abou Jamra, Rami

    2016-06-01

    PTEN hamartoma tumour syndrome (PHTS) is caused by heterozygous variants in PTEN and is characterised by tumour predisposition, macrocephaly, and cognition impairment. Bi-allelic loss of PTEN activity has not been reported so far and animal models suggest that bi-allelic loss of PTEN activity is embryonically lethal. Here, we report the identification of a novel homozygous variant in PTEN, NM_000314.4; c.545T>C; p.Leu182Ser, in two adolescent siblings with severe macrocephaly and mild intellectual disability. The variant is predicted to be damaging and is associated with significantly increased phospho-S6 downstream of PTEN. The absence of tumours in the two homozygous siblings as well as lack of symptoms of PHTS in the heterozygous carriers of the family suggest that this particular variant is functionally hypomorphic rather than deleterious.

  19. Resistance of Microorganisms to Extreme Environmental Conditions and Its Contribution to Astrobiology

    Directory of Open Access Journals (Sweden)

    Pabulo Henrique Rampelotto

    2010-06-01

    Full Text Available In the last decades, substantial changes have occurred regarding what scientists consider the limits of habitable environmental conditions. For every extreme environmental condition investigated, a variety of microorganisms have shown that not only can they tolerate these conditions, but that they also often require these extreme conditions for survival. Microbes can return to life even after hundreds of millions of years. Furthermore, a variety of studies demonstrate that microorganisms can survive under extreme conditions, such as ultracentrifugation, hypervelocity, shock pressure, high temperature variations, vacuums, and different ultraviolet and ionizing radiation intensities, which simulate the conditions that microbes could experience during the ejection from one planet, the journey through space, as well as the impact in another planet. With these discoveries, our knowledge about the biosphere has grown and the putative boundaries of life have expanded. The present work examines the recent discoveries and the principal advances concerning the resistance of microorganisms to extreme environmental conditions, and analyzes its contributions to the development of the main themes of astrobiology: the origins of life, the search for extraterrestrial life, and the dispersion of life in the Universe.

  20. CO Cleavage and CO2 Functionalization under Mild Conditions by a Multimetallic CsU2 Nitride Complex.

    Science.gov (United States)

    Falcone, Marta; Chatelain, Lucile; Scopelliti, Rosario; Mazzanti, Marinella

    2017-04-26

    Novel efficient chemical processes involving cheap and widely accessible carbon dioxide or carbon monoxide under mild conditions for the production of valuable chemical products are highly desirable in the current energetic context. Uranium nitride materials act as high activity catalysts in the Haber-Bosch process but the reactivity of molecular nitride compounds remains unexplored. Here we review recent results obtained in our group showing that a multimetallic nitride complex [Cs{[U(OSi(OtBu)3)3]2(μ-N)}] (1) with a CsUIV-N-UIV core, is able to promote N-C bond formation due to its strong nucleophile behaviour. In particular, complex 1, in the presence of excess CO2 leads to a remarkable dicarbamate product. The multimetallic CsUIV-N-UIV nitride also readily cleaves the C≡O bond under mild conditions.

  1. Extreme groundwater levels caused by extreme weather conditions - the highest ever measured groundwater levels in Middle Germany and their management

    Science.gov (United States)

    Reinstorf, F.; Kramer, S.; Koch, T.; Pfützner, B.

    2017-12-01

    Extreme weather conditions during the years 2009 - 2011 in combination with changes in the regional water management led to maximum groundwater levels in large areas of Germany in 2011. This resulted in extensive water logging, with problems especially in urban areas near rivers, where water logging produced huge problems for buildings and infrastructure. The acute situation still exists in many areas and requires the development of solution concepts. Taken the example of the Elbe-Saale-Region in the Federal State of Saxony-Anhalt, were a pilot research project was carried out, the analytical situation, the development of a management tool and the implementation of a groundwater management concept are shown. The central tool is a coupled water budget - groundwater flow model. In combination with sophisticated multi-scale parameter estimation, a high-resolution groundwater level simulation was carried out. A decision support process with an intensive stakeholder interaction combined with high-resolution simulations enables the development of a management concept for extreme groundwater situations in consideration of sustainable and environmentally sound solutions mainly on the base of passive measures.

  2. Rh(III) -Catalyzed C-H Olefination of Benzoic Acids under Mild Conditions using Oxygen as the Sole Oxidant.

    Science.gov (United States)

    Jiang, Quandi; Zhu, Changlei; Zhao, Huaiqing; Su, Weiping

    2016-02-04

    Phthalide skeletons have been synthesized for the first time through a Rh(III) -catalyzed C-H olefination of benzoic acids under mild conditions using oxygen as the sole oxidant. Aromatic acids bearing a variety of functional groups could react with diverse alkenes to afford the desired cyclized lactones or uncyclized alkenylarenes in moderate-to-excellent yields. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  3. Proceedings of the second symposium on science of hadrons under extreme conditions

    International Nuclear Information System (INIS)

    Chiba, Satoshi

    2000-08-01

    The second symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on January 24 to 26, 2000. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as nuclear matter, high-energy nuclear reactions, quantum chromodynamics, supernovae and nucleosynthesis to understand various aspects of hadrons under extreme conditions. The 26 of the presented papers are indexed individually. (J.P.N.)

  4. "On-off-on" switchable sensor: a fluorescent spiropyran responds to extreme pH conditions and its bioimaging applications.

    Science.gov (United States)

    Wan, Shulin; Zheng, Yang; Shen, Jie; Yang, Wantai; Yin, Meizhen

    2014-11-26

    A novel spiropyran that responds to both extreme acid and extreme alkali and has an "on-off-on" switch is reported. Benzoic acid at the indole N-position and carboxyl group at the indole 6-position contribute to the extreme acid response. The ionizations of carboxyl and phenolic hydroxyl groups cause the extreme alkali response. Moreover, the fluorescent imaging in bacterial cells under extreme pH conditions supports the mechanism of pH response.

  5. Mild neonatal hyperthyrotrophinaemia: 10-year experience suggests the condition is increasingly common but often transient.

    Science.gov (United States)

    Oren, Asaf; Wang, Michael K; Brnjac, Lori; Mahmud, Farid H; Palmert, Mark R

    2013-12-01

    To examine a large population of infants with mild neonatal hyperthyrotrophinaemia (MNH) and determine prevalence, clinical characteristics and treatment history. Retrospective study of infants with MNH followed at The Hospital for Sick Children between 2000 and 2011. MNH was defined by an abnormal newborn screen followed by thyroid-stimulating hormone (TSH) between 5 and 30 mU/l and normal free T4 (FT4) on confirmatory tests. Mild neonatal hyperthyrotrophinaemia represented 22·3% of patients (103/462; 60 boys, 43 girls) within our clinic. Incidence increased from two of 20 in 2000 to 31 of 74 cases in 2010. Seventy eight percent of patients started L-thyroxine (initial dose: 8·3 ± 2·5 mcg/kg). The treated group had higher confirmatory TSH levels (P = 0·001) and had undergone thyroid scintigraphy more often (P = 0·0001) compared with the nontreated group. Evidence of overtreatment was detected in 45% of thyroid function tests obtained during treatment. Among the treated infants who had reached 3 years of age, 45% (N = 14) underwent a trial-off medication. Compared with those not trialled-off therapy, these infants were less likely to have had dose escalations during treatment (P = 0·001). The trial-off treatment was successful in 50% of cases. In the subset of infants with confirmatory TSH >10 mU/l, trial-off therapy was successful in 40%. None of the assessed variables predicted success of trial-off therapy. Mild neonatal hyperthyrotrophinaemia is an increasingly common diagnosis. It is more common in males and is often transient, but predictors of success of trial-off therapy were not identified. Further studies are needed to determine optimum L-thyroxine dosing and to determine whether treatment improves neurocognitive outcomes. © 2013 John Wiley & Sons Ltd.

  6. Examination of the interaction of different lighting conditions and chronic mild stress in animal model.

    Science.gov (United States)

    Muller, A; Gal, N; Betlehem, J; Fuller, N; Acs, P; Kovacs, G L; Fusz, K; Jozsa, R; Olah, A

    2015-09-01

    We examined the effects of different shift work schedules and chronic mild stress (CMS) on mood using animal model. The most common international shift work schedules in nursing were applied by three groups of Wistar-rats and a control group with normal light-dark cycle. One subgroup from each group was subjected to CMS. Levels of anxiety and emotional life were evaluated in light-dark box. Differences between the groups according to independent and dependent variables were examined with one- and two-way analysis of variance, with a significance level defined at p animals.

  7. The Extreme Male Brain Theory and Gender Role Behaviour in Persons with an Autism Spectrum Condition

    Science.gov (United States)

    Stauder, J. E. A.; Cornet, L. J. M.; Ponds, R. W. H. M.

    2011-01-01

    According to the Extreme Male Brain theory persons with autism possess masculinised cognitive traits. In this study masculinisation of gender role behaviour is evaluated in 25 persons with an autism spectrum condition (ASC) and matched controls with gender role behaviour as part of a shortened version of the Minnesota Multiphasic Personality…

  8. Probing the local, electronic and magnetic structure of matter under extreme conditions of temperature and pressure

    DEFF Research Database (Denmark)

    Torchio, R.; Boccato, S.; Cerantola, V.

    2016-01-01

    In this paper we present recent achievements in the field of investigation of the local, electronic and magnetic structure of the matter under extreme conditions of pressure and temperature. These results were obtained thanks to the coupling of a compact laser heating system to the energy-dispersive...

  9. Atmospheric conditions and weather regimes associated with extreme winter dry spells over the Mediterranean basin

    Science.gov (United States)

    Raymond, Florian; Ullmann, Albin; Camberlin, Pierre; Oueslati, Boutheina; Drobinski, Philippe

    2018-06-01

    Very long dry spell events occurring during winter are natural hazards to which the Mediterranean region is extremely vulnerable, because they can lead numerous impacts for environment and society. Four dry spell patterns have been identified in a previous work. Identifying the main associated atmospheric conditions controlling the dry spell patterns is key to better understand their dynamics and their evolution in a changing climate. Except for the Levant region, the dry spells are generally associated with anticyclonic blocking conditions located about 1000 km to the Northwest of the affected area. These anticyclonic conditions are favourable to dry spell occurrence as they are associated with subsidence of cold and dry air coming from boreal latitudes which bring low amount of water vapour and non saturated air masses, leading to clear sky and absence of precipitation. These extreme dry spells are also partly related to the classical four Euro-Atlantic weather regimes are: the two phases of the North Atlantic Oscillation, the Scandinavian "blocking" or "East-Atlantic", and the "Atlantic ridge". Only the The "East-Atlantic", "Atlantic ridge" and the positive phase of the North Atlantic Oscillation are frequently associated with extremes dry spells over the Mediterranean basin but they do not impact the four dry spell patterns equally. Finally long sequences of those weather regimes are more favourable to extreme dry spells than short sequences. These long sequences are associated with the favourable prolonged and reinforced anticyclonic conditions

  10. On the Performance of Carbon Nanotubes in Extreme Conditions and in the Presence of Microwaves

    Science.gov (United States)

    2013-01-01

    been considered for use as transparent conductors include: transparent conducting oxides (TCOs), intrinsically conducting polymers (ICPs), graphene ...optical transmission properties, but are extremely sensitive to environmental conditions (such as temperature and humidity). Graphene has recently...during the dicing procedure, silver paint was applied to the sample to serve as improvised contact/probe-landing points. Figure 1 shows the CNT thin

  11. Numerical tools to predict the environmental loads for offshore structures under extreme weather conditions

    Science.gov (United States)

    Wu, Yanling

    2018-05-01

    In this paper, the extreme waves were generated using the open source computational fluid dynamic (CFD) tools — OpenFOAM and Waves2FOAM — using linear and nonlinear NewWave input. They were used to conduct the numerical simulation of the wave impact process. Numerical tools based on first-order (with and without stretching) and second-order NewWave are investigated. The simulation to predict force loading for the offshore platform under the extreme weather condition is implemented and compared.

  12. Influence of the emotional state on behavior in extreme conditions of competitive sports activities

    Directory of Open Access Journals (Sweden)

    V.A. Malakhov

    2014-04-01

    Full Text Available Purpose : establish a communication pattern of emotional intensity and level of extreme environment in which activity is performed. Materials : in the study involved 600 men aged 18-22 years. Results : the effect of the emotional state on the efficiency of the motor activity that flowed under extreme conditions. Set individual characteristics flow sports activities in extreme conditions. First used in the special semantic space for the orderly presentation of research results parachute jumps. The monogram built in semantic fields allows to establish the frequency response range of individual heartbeats and the optimal frequency for maximum performance. On the basis of established regularities of the "reflex of readiness" assessment methodology given emotional stress, which reflects the readiness of an individual to perform a parachute jump. An objective indicator of preparedness measures is a violation of the symmetry of the flow and haptic reflex and serial dynamometry. Conclusions : in using semantic spaces reflects the flowing of reflex of biological caution and accompaniment reflex. In the basis of constructing estimates of emotional stress are the regularities of mean arterial pressure as nonspecific reactions. Measure of extent of confused is estimated by variability of accompaniment reflex. Breach of symmetry in mean arterial pressure and the amplitude - frequency response accompaniment reflex, determine the validity of staying in extreme conditions. Introduction of the measure in using semantic spaces allows by selective data to establish the overall structure of the studied process.

  13. Influence of the emotional state on behavior in extreme conditions of competitive sports activities

    Directory of Open Access Journals (Sweden)

    Malakhov V.A.

    2014-03-01

    Full Text Available Purpose : establish a communication pattern of emotional intensity and level of extreme environment in which activity is performed. Materials : in the study involved 600 men aged 18-22 years. Results : the effect of the emotional state on the efficiency of the motor activity that flowed under extreme conditions. Set individual characteristics flow sports activities in extreme conditions. First used in the special semantic space for the orderly presentation of research results parachute jumps. The monogram built in semantic fields allows to establish the frequency response range of individual heartbeats and the optimal frequency for maximum performance. On the basis of established regularities of the "reflex of readiness" assessment methodology given emotional stress, which reflects the readiness of an individual to perform a parachute jump. An objective indicator of preparedness measures is a violation of the symmetry of the flow and haptic reflex and serial dynamometry. Conclusions : in using semantic spaces reflects the flowing of reflex of biological caution and accompaniment reflex. In the basis of constructing estimates of emotional stress are the regularities of mean arterial pressure as nonspecific reactions. Measure of extent of confused is estimated by variability of accompaniment reflex. Breach of symmetry in mean arterial pressure and the amplitude - frequency response accompaniment reflex, determine the validity of staying in extreme conditions. Introduction of the measure in using semantic spaces allows by selective data to establish the overall structure of the studied process.

  14. Mechanical characterization of alloys in extreme conditions of high strain rates and high temperature

    Science.gov (United States)

    Cadoni, Ezio

    2018-03-01

    The aim of this paper is the description of the mechanical characterization of alloys under extreme conditions of temperature and loading. In fact, in the frame of the Cost Action CA15102 “Solutions for Critical Raw Materials Under Extreme Conditions (CRM-EXTREME)” this aspect is crucial and many industrial applications have to consider the dynamic response of materials. Indeed, for a reduction and substitution of CRMs in alloys is necessary to design the materials and understand if the new materials behave better or if the substitution or reduction badly affect their performance. For this reason, a deep knowledge of the mechanical behaviour at high strain-rates of considered materials is required. In general, machinery manufacturing industry or transport industry as well as energy industry have important dynamic phenomena that are simultaneously affected by extended strain, high strain-rate, damage and pressure, as well as conspicuous temperature gradients. The experimental results in extreme conditions of high strain rate and high temperature of an austenitic stainless steel as well as a high-chromium tempered martensitic reduced activation steel Eurofer97 are presented.

  15. Improving multisensor estimation of heavy-to-extreme precipitation via conditional bias-penalized optimal estimation

    Science.gov (United States)

    Kim, Beomgeun; Seo, Dong-Jun; Noh, Seong Jin; Prat, Olivier P.; Nelson, Brian R.

    2018-01-01

    A new technique for merging radar precipitation estimates and rain gauge data is developed and evaluated to improve multisensor quantitative precipitation estimation (QPE), in particular, of heavy-to-extreme precipitation. Unlike the conventional cokriging methods which are susceptible to conditional bias (CB), the proposed technique, referred to herein as conditional bias-penalized cokriging (CBPCK), explicitly minimizes Type-II CB for improved quantitative estimation of heavy-to-extreme precipitation. CBPCK is a bivariate version of extended conditional bias-penalized kriging (ECBPK) developed for gauge-only analysis. To evaluate CBPCK, cross validation and visual examination are carried out using multi-year hourly radar and gauge data in the North Central Texas region in which CBPCK is compared with the variant of the ordinary cokriging (OCK) algorithm used operationally in the National Weather Service Multisensor Precipitation Estimator. The results show that CBPCK significantly reduces Type-II CB for estimation of heavy-to-extreme precipitation, and that the margin of improvement over OCK is larger in areas of higher fractional coverage (FC) of precipitation. When FC > 0.9 and hourly gauge precipitation is > 60 mm, the reduction in root mean squared error (RMSE) by CBPCK over radar-only (RO) is about 12 mm while the reduction in RMSE by OCK over RO is about 7 mm. CBPCK may be used in real-time analysis or in reanalysis of multisensor precipitation for which accurate estimation of heavy-to-extreme precipitation is of particular importance.

  16. What are extreme environmental conditions and how do organisms cope with them?

    Directory of Open Access Journals (Sweden)

    John C. WINGFIELD, J. Patrick KELLEY, Frédéric ANGELIER

    2011-06-01

    Full Text Available Severe environmental conditions affect organisms in two major ways. The environment may be predictably severe such as in deserts, polar and alpine regions, or individuals may be exposed to temporarily extreme conditions through weather, presence of predators, lack of food, social status etc. Existence in an extreme environment may be possible, but then to breed or molt in addition can present major bottlenecks that have resulted in the evolution of hormone-behavior adaptations to cope with unpredictable events. Examples of hormone-behavior adaptations in extreme conditions include attenuated testosterone secretion because territoriality and excess courtship may be too costly when there is one opportunity to reproduce. The individual may even become insensitive to testosterone when target areas of the brain regulating reproductive behavior no longer respond to the hormone. A second example is reduced sensitivity to glucocorticoids following acute stress during the breeding season or molt that allows successful reproduction and/or a vital renewal of the integument to endure extreme conditions during the rest of the year. Reduced sensitivity could involve: (a modulated response of the hypothalamo-pituitary-adrenal axis, (b reduced sensitivity to high glucocorticoid levels, or (c a combination of (a and (b. Moreover, corticosteroid binding proteins (CBP buffer responses to stress by reducing the movement of glucocorticoids into target cells. Finally, intracellular enzymes (11b-hydroxysteroid dehydrogenase and variants can deactivate glucocorticoids entering cells thus reducing interaction with receptors. These mechanisms have important implications for climate change and increasing extremes of weather [Current Zoology 57 (3: 363–374, 2011].

  17. High-energy synchrotron x-ray diffraction studies on disordered materials. From ambient condition to an extreme condition

    International Nuclear Information System (INIS)

    Kohara, Shinji; Ohishi, Yasuo; Suzuya, Kentaro; Takata, Masaki

    2007-01-01

    High-energy x-rays from synchrotron radiation source allow us to measure high-quality diffraction data of the disordered materials from under ambient condition to an extreme condition, which is necessary to reveal the detailed structure of glass, liquid, and amorphous materials. We introduce the high-energy x-ray diffraction beamline and dedicated diffractometer for glass, liquid, and amorphous materials with the recent developments of ancillary equipments. Furthermore our recent studies on the structures of disordered materials reviewed. (author)

  18. Mild hypothermic culture conditions affect residual host cell protein composition post-Protein A chromatography.

    Science.gov (United States)

    Goey, Cher Hui; Bell, David; Kontoravdi, Cleo

    2018-04-01

    Host cell proteins (HCPs) are endogenous impurities, and their proteolytic and binding properties can compromise the integrity, and, hence, the stability and efficacy of recombinant therapeutic proteins such as monoclonal antibodies (mAbs). Nonetheless, purification of mAbs currently presents a challenge because they often co-elute with certain HCP species during the capture step of protein A affinity chromatography. A Quality-by-Design (QbD) strategy to overcome this challenge involves identifying residual HCPs and tracing their source to the harvested cell culture fluid (HCCF) and the corresponding cell culture operating parameters. Then, problematic HCPs in HCCF may be reduced by cell engineering or culture process optimization. Here, we present experimental results linking cell culture temperature and post-protein A residual HCP profile. We had previously reported that Chinese hamster ovary cell cultures conducted at standard physiological temperature and with a shift to mild hypothermia on day 5 produced HCCF of comparable product titer and HCP concentration, but with considerably different HCP composition. In this study, we show that differences in HCP variety at harvest cascaded to downstream purification where different residual HCPs were present in the two sets of samples post-protein A purification. To detect low-abundant residual HCPs, we designed a looping liquid chromatography-mass spectrometry method with continuous expansion of a preferred, exclude, and targeted peptide list. Mild hypothermic cultures produced 20% more residual HCP species, especially cell membrane proteins, distinct from the control. Critically, we identified that half of the potentially immunogenic residual HCP species were different between the two sets of samples.

  19. Corrosion behavior of mild steel and SS 304L in presence of dissolved nickel under aerated and deaerated conditions

    Directory of Open Access Journals (Sweden)

    Mohd Mobin

    2011-12-01

    Full Text Available In dual purpose water/power co-generation plants, the presence of high concentration of Cu and Ni in the re-circulating brine/condensate as a result of condenser tubes corrosion has been attributed as one of the several causes of corrosion damage of flash chamber materials and water touched parts of the boilers. The present investigation deals with the effect of dissolved nickel in the concentration range of 10 ppb to 100 ppm on the corrosion behavior of mild steel and SS 304L in two aqueous medium namely, distilled water and artificial seawater. The effect of pH, dissolved oxygen and flow condition of aqueous medium on the corrosion behavior was also monitored. The experimental techniques include immersion test and electrochemical tests which include free corrosion potential measurements and potentiodynamic polarization measurements. The corrosion rate of mild steel and SS 304L under different experimental conditions was determined by weight loss method and spectrophotometric determination of iron ion entered into the test solution during the period of immersion. The pH of the test solution was also monitored during the entire period of immersion. The left over nickel ions present in the test solution after completion of immersion was also estimated using Atomic Absorption Spectrophotometer. The surface morphology of the corroded steel surface was also examined using scanning electron microscopy (SEM. The results of the studies show that SS 304L largely remains unaffected in both distilled water and artificial seawater under different experimental conditions. However, the effect of nickel on the corrosion behavior of mild steel is quite pronounced and follows interesting trends.

  20. Efficient and facile one pot carboxylation of multiwalled carbon nanotubes by using oxidation with ozone under mild conditions

    International Nuclear Information System (INIS)

    Naeimi, Hossein; Mohajeri, Ali; Moradi, Leila; Rashidi, Ali Morad

    2009-01-01

    Graphical abstract: In this work, oxidation of carbon nanotubes with ozone in the presence of hydrogen peroxide was studied. The reactions were performed under clean and mild conditions and oxidized products with high concentration of oxygenated groups were yielded. The reaction products were characterized with attenuated total reflectance (ATR), Raman spectroscopy, scanning electron microscopy (SEM), X-ray diffractometry (XRD), back titration, X-ray photoelectron spectroscopy (XPS) and the dispersion behavior of the oxidized multiwalled carbon nanotubes (MWCNTs) was also studied. The results confirmed the presence of high concentrations of oxidative groups on the carbon nanotubes (CNTs) treated by the method of the present work.

  1. Mild Conditions for Deuteration of Primary and Secondary Arylamines for the Synthesis of Deuterated Optoelectronic Organic Molecules

    Directory of Open Access Journals (Sweden)

    Anwen M. Krause-Heuer

    2014-11-01

    Full Text Available Deuterated arylamines demonstrate great potential for use in optoelectronic devices, but their widespread utility requires a method for large-scale synthesis. The incorporation of these deuterated materials into optoelectronic devices also provides the opportunity for studies of the functioning device using neutron reflectometry based on the difference in the scattering length density between protonated and deuterated compounds. Here we report mild deuteration conditions utilising standard laboratory glassware for the deuteration of: diphenylamine, N-phenylnaphthylamine, N-phenyl-o-phenylenediamine and 1-naphthylamine (via H/D exchange in D2O at 80 °C, catalysed by Pt/C and Pd/C. These conditions were not successful in the deuteration of triphenylamine or N,N-dimethylaniline, suggesting that these mild conditions are not suitable for the deuteration of tertiary arylamines, but are likely to be applicable for the deuteration of other primary and secondary arylamines. The deuterated arylamines can then be used for synthesis of larger organic molecules or polymers with optoelectronic applications.

  2. EMA beamline at SIRIUS: extreme condition X-ray methods of analysis

    International Nuclear Information System (INIS)

    Souza Neto, Narcizo

    2016-01-01

    Full text: The EMA beamline (Extreme condition X-ray Methods of Analysis) is one of the hard x-ray undulator beamlines within the first phase of the new synchrotron source in Brazil (Sirius project). This beamline is thought to make a difference where a high brilliance (high flux of up to 2 x 10 14 photons/sec with beam size down to 0.5 x 0.5 μm 2 ) is essential, which is the case for extreme pressures that require small focus and time-resolved that require high photon flux. With that in mind we propose the beamline to have two experimental hutches to cover most of the extreme condition techniques today employed at synchrotron laboratories worldwide. These two stations are thought to provide the general infrastructure for magnets and lasers experiments, which may evolve as new scientific problems appear. In addition to the hutches, support laboratories will be strongly linked and supportive to the experiments at the beamline, covering high pressure instrumentations using diamond anvil cells and pump-and-probe requirements for ultrafast and high power lasers. Along these lines, we will describe the following techniques covered at this beamline: magnetic spectroscopy (XMCD) and scattering (XRMS) under high pressure and very low temperature in order to fully probe both ferromagnetic and antiferromagnetic materials and the dependence with pressure; extreme pressure and temperature XRD and XAS experiments using very small diamond culet anvils and high power lasers. (author)

  3. EMA beamline at SIRIUS: extreme condition X-ray methods of analysis

    Energy Technology Data Exchange (ETDEWEB)

    Souza Neto, Narcizo, E-mail: narcizo.souza@lnls.br [Centro Nacional de Pesquisa em Energia e Materiais (CNPEM), Campinas, SP (Brazil)

    2016-07-01

    Full text: The EMA beamline (Extreme condition X-ray Methods of Analysis) is one of the hard x-ray undulator beamlines within the first phase of the new synchrotron source in Brazil (Sirius project). This beamline is thought to make a difference where a high brilliance (high flux of up to 2 x 10{sup 14} photons/sec with beam size down to 0.5 x 0.5 μm{sup 2}) is essential, which is the case for extreme pressures that require small focus and time-resolved that require high photon flux. With that in mind we propose the beamline to have two experimental hutches to cover most of the extreme condition techniques today employed at synchrotron laboratories worldwide. These two stations are thought to provide the general infrastructure for magnets and lasers experiments, which may evolve as new scientific problems appear. In addition to the hutches, support laboratories will be strongly linked and supportive to the experiments at the beamline, covering high pressure instrumentations using diamond anvil cells and pump-and-probe requirements for ultrafast and high power lasers. Along these lines, we will describe the following techniques covered at this beamline: magnetic spectroscopy (XMCD) and scattering (XRMS) under high pressure and very low temperature in order to fully probe both ferromagnetic and antiferromagnetic materials and the dependence with pressure; extreme pressure and temperature XRD and XAS experiments using very small diamond culet anvils and high power lasers. (author)

  4. Distribution patterns of terricolous and saxicolous lichens in extreme desert conditions

    Science.gov (United States)

    Temina, M.

    2012-04-01

    The investigation of biodiversity in stressful habitats is of great interest because it elucidates relationships between organisms and their environment, as well as revealing the mechanisms of their survival and adaptation to extreme conditions. Deserts represent such stressful habitats where harsh climate and limited resources greatly influence the formation of biota. In order to understand the link between microscale environmental variability in extreme arid conditions and lichen biodiversity patterns, we conducted the present study. For this purpose, the structure and distribution of lichen communities on soil and cobbles at six stations at "Evolution Canyon" III (EC III), Nahal Shaharut, in the extreme southern Negev, Israel, were examined. The opposite slopes of the canyon represented specific ecological niches characterized by sharply different microclimatic conditions. The following characteristics of lichen communities were studied: species richness, systematic diversity, biogeographical elements, frequencies and distribution of species, their morphological and anatomical characteristics, reproductive strategy, and ecological peculiarities. In the research site three environmental variables were evaluated: soil moisture, and temperatures of soil and cobbles. The Canonical Correspondence Analysis was used to study the influence of these ecological variables on the distribution of lichen species. The lichen diversity of EC III was very poor and comprised 12 species (3 cyanoliches on soil vs. 9 phycolichens on cobbles). Most of them belong to a specific group of arid endemic elements, adapted to survive in extreme arid conditions in the deserts of the Levant. The harsh desert conditions of the canyon negatively influence the reproductive ability of lichens. This influence is expressed in the decreased sizes of fruit bodies in some species, and the frequent occurrence of sterile specimens among lichens found in the canyon. A comparative analysis of structure

  5. Thermoregulatory value of cracking-clay soil shelters for small vertebrates during extreme desert conditions.

    Science.gov (United States)

    Waudby, Helen P; Petit, Sophie

    2017-05-01

    Deserts exhibit extreme climatic conditions. Small desert-dwelling vertebrates have physiological and behavioral adaptations to cope with these conditions, including the ability to seek shelter. We investigated the temperature (T) and relative humidity (RH) regulating properties of the soil cracks that characterize the extensive cracking-clay landscapes of arid Australia, and the extent of their use by 2 small marsupial species: fat-tailed and stripe-faced dunnarts (Sminthopsis crassicaudata and Sminthopsis macroura). We measured hourly (over 24-h periods) the T and RH of randomly-selected soil cracks compared to outside conditions, during 2 summers and 2 winters. We tracked 17 dunnarts (8 Sminthopsis crassicaudata and 9 Sminthopsis macroura) to quantify their use of cracks. Cracks consistently moderated microclimate, providing more stable conditions than available from non-crack points, which often displayed comparatively dramatic fluctuations in T and RH. Both dunnart species used crack shelters extensively. Cracks constitute important shelter for small animals during extreme conditions by providing a stable microclimate, which is typically cooler than outside conditions in summer and warmer in winter. Cracks likely play a fundamental sheltering role by sustaining the physiological needs of small mammal populations. Globally, cracking-clay areas are dominated by agricultural land uses, including livestock grazing. Management of these systems should focus not only on vegetation condition, but also on soil integrity, to maintain shelter resources for ground-dwelling fauna. © 2016 International Society of Zoological Sciences, Institute of Zoology/Chinese Academy of Sciences and John Wiley & Sons Australia, Ltd.

  6. Inelastic X-ray scattering experiments at extreme conditions: high temperatures and high pressures

    Directory of Open Access Journals (Sweden)

    S.Hosokawa

    2008-03-01

    Full Text Available In this article, we review the present status of experimental techniques under extreme conditions of high temperature and high pressure used for inelastic X-ray scattering (IXS experiments of liquid metals, semiconductors, molten salts, molecular liquids, and supercritical water and methanol. For high temperature experiments, some types of single-crystal sapphire cells were designed depending on the temperature of interest and the sample thickness for the X-ray transmission. Single-crystal diamond X-ray windows attached to the externally heated high-pressure vessel were used for the IXS experiment of supercritical water and methanol. Some typical experimental results are also given, and the perspective of IXS technique under extreme conditions is discussed.

  7. Proceedings of the third symposium on science of hadrons under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, Satoshi (ed.) [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-09-01

    The third symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on January 29 to 31, 2001. The symposium was devoted for discussions and presentations of research results in wide variety of hadron physics such as nuclear matter, high-energy nuclear reactions, quantum chromodynamics, neutron stars, supernovae, nucleosynthesis as well as finite nuclei to understand various aspects of hadrons under extreme conditions. Twenty two papers on these topics presented at the symposium, including a special talk on the present status of JAERI-KEK joint project on high-intensity proton accelerator, aroused lively discussions among approximately 40 participants. The 20 of the presented papers are indexed individually. (J.P.N.)

  8. In-situ transmission electron microscopy growth of nanoparticles under extreme conditions

    International Nuclear Information System (INIS)

    Luce, F. P.; Azevedo, G. de M.; Baptista, D. L.; Zawislak, F. C.; Oliviero, E.; Fichtner, P. F. P.

    2016-01-01

    The formation and time resolved behavior of individual Pb nanoparticles embedded in silica have been studied by in-situ transmission electron microscopy observations at high temperatures (400–1100 °C) and under 200 keV electron irradiation. It is shown that under such extreme conditions, nanoparticles can migrate at long distances presenting a Brownian-like behavior and eventually coalesce. The particle migration phenomenon is discussed considering the influence of the thermal energy and the electron irradiation effects on the atomic diffusion process which is shown to control particle migration. These results and comparison with ex-situ experiments tackle the stability and the microstructure evolution of nanoparticles systems under extreme conditions. It elucidates on the effects of energetic particle irradiation-annealing treatments either as a tool or as a detrimental issue that could hamper their long-term applications in radiation-harsh environments such as in space or nuclear sectors

  9. Extreme conditions over Europe and North America: role of the Atlantic Multidecadal Variability

    Science.gov (United States)

    Ruprich-Robert, Yohan; Msadek, Rym; Delworth, Tom

    2016-04-01

    The Atlantic Multidecadal Variability (AMV) is the result and possibly the source of marked modulations of the climate over many areas of the globe. For instance, the relatively warm and dry climate of North America throughout the 30-yr interval of 1931-60, during which the Dust Bowl and the 1950's drought occurred, has been linked to the concomitant warm phase of the AMV. During this period relative warm and wet conditions prevailed over Europe. After 1960, the Atlantic began to cool, and for almost three decades the North American climate turned wetter and cooler whereas Europe experienced cooler and dryer conditions. However, the shortness of the historical observations compared to the AMV period suggested by longer proxy (~60-80yr) does not allow to firmly conclude on the causal effect of the AMV. We use a model approach to isolate the causal role of the AMV on the occurrence of extreme events over Europe and North America. We present experiments based on two GFDL global climate models, a low resolution version, CM2.1 and a higher resolution model for the atmospheric component, FLOR. In both model experiments sea surface temperatures in the North Atlantic sector are restored to the observed AMV pattern, while the other basins are left fully coupled. In order to explore and robustly isolate the AMV impacts on extreme events, we use large ensemble simulations (100 members for CM2.1 and 50 for FLOR) that we run for 20 years. We find that a positive phase of the AMV increases the frequency of occurrence of drought over North America and of extremely cold/warm conditions over Northern/Central Europe during winter/summer. Interestingly, we find that the AMV impacts on these extreme conditions are modulated by the Pacific response to the AMV itself. Members that develop a weak Pacific response show more extreme events over Europe whereas those that develop a strong Pacific response show more extreme events over North America.

  10. Life at extreme conditions: neutron scattering studies of biological molecules suggest that evolution selected dynamics

    International Nuclear Information System (INIS)

    Zaccai, Joseph Giuseppe

    2008-01-01

    The short review concentrates on recent work performed at the neutrons in biology laboratories of the Institut Laue Langevin and Institut de Biologie Structurale in Grenoble. Extremophile organisms have been discovered that require extreme conditions of temperature, pressure or solvent environment for survival. The existence of such organisms poses a significant challenge in understanding the physical chemistry of their proteins, in view of the great sensitivity of protein structure and stability to the aqueous environment and to external conditions in general. Results of neutron scattering measurements on the dynamics of proteins from extremophile organisms, in vitro as well as in vivo, indicated remarkably how adaptation to extreme conditions involves forces and fluctuation amplitudes that have been selected specifically, suggesting that evolutionary macromolecular selection proceeded via dynamics. The experiments were performed on a halophilic protein, and membrane adapted to high salt, a thermophilic enzyme adapted to high temperature and its mesophilic (adapted to 37 degC) homologue; and in vivo for psychrophilic, mesophilic, thermophilic and hyperthermophilic bacteria, adapted respectively to temperatures of 4 degC, 37 degC, 75 degC and 85 degC. Further work demonstrated the existence of a water component of exceptionally low mobility in an extreme halophile from the Dead Sea, which is not present in mesophile bacterial cells. (author)

  11. Production of starch nanoparticles using normal maize starch via heat-moisture treatment under mildly acidic conditions and homogenization.

    Science.gov (United States)

    Park, Eun Young; Kim, Min-Jung; Cho, MyoungLae; Lee, Ju Hun; Kim, Jong-Yea

    2016-10-20

    Normal maize starch was subjected to heat-moisture treatment (HMT) under mildly acidic conditions (0.000, 0.050, or 0.075M H2SO4) for various treatment times (3, 5, or 8h) followed by homogenization up to 60min to prepare nanoparticles. The combination of HMT (0.075M, for 8h) and homogenization (60min) produced nanoparticles with diameters of less than 50nm at a yield higher than 80%. X-ray diffractometry and size-exclusion chromatography revealed that HMT under mildly acidic conditions selectively hydrolyzed the starch chains (especially amylose and/or long chains of amylopectin) in the amorphous region of the granules without significant damage to the crystalline structure, however, modification of the molecular structure in the amorphous region increased fragility of the granules during homogenization. Homogenization for 60min caused obvious damage in the long-range crystalline structure of the HMT starch (0.15N, for 8h), while the short-range chain associations (FT-IR) remained intact. Copyright © 2016 Elsevier Ltd. All rights reserved.

  12. A new and selective cycle for dehydrogenation of linear and cyclic alkanes under mild conditions using a base metal

    Science.gov (United States)

    Solowey, Douglas P.; Mane, Manoj V.; Kurogi, Takashi; Carroll, Patrick J.; Manor, Brian C.; Baik, Mu-Hyun; Mindiola, Daniel J.

    2017-11-01

    Selectively converting linear alkanes to α-olefins under mild conditions is a highly desirable transformation given the abundance of alkanes as well as the use of olefins as building blocks in the chemical community. Until now, this reaction has been primarily the remit of noble-metal catalysts, despite extensive work showing that base-metal alkylidenes can mediate the reaction in a stoichiometric fashion. Here, we show how the presence of a hydrogen acceptor, such as the phosphorus ylide, when combined with the alkylidene complex (PNP)Ti=CHtBu(CH3) (PNP=N[2-P(CHMe2)2-4-methylphenyl]2-), catalyses the dehydrogenation of cycloalkanes to cyclic alkenes, and linear alkanes with chain lengths of C4 to C8 to terminal olefins under mild conditions. This Article represents the first example of a homogeneous and selective alkane dehydrogenation reaction using a base-metal titanium catalyst. We also propose a unique mechanism for the transfer dehydrogenation of hydrocarbons to olefins and discuss a complete cycle based on a combined experimental and computational study.

  13. Organizing of medical ensurance of human population under extreme conditions. Summaries of reports of scientific-practical conference

    International Nuclear Information System (INIS)

    1994-01-01

    Summary of reports are presented of Scientific-Practical conference on the organizing of medical ensurance of human population under extreme conditions including radiation accidents. The conference held in Moscow in October, 1994. It covered problems of organizing medical ensurance of population, medical surveillance problems, sanitary-hygienic and epidemiological problems (including radiation protection), and medical provision problems under extreme conditions

  14. Life under Multiple Extreme Conditions: Diversity and Physiology of the Halophilic Alkalithermophiles

    Science.gov (United States)

    Wiegel, Juergen

    2012-01-01

    Around the world, there are numerous alkaline, hypersaline environments that are heated either geothermally or through intense solar radiation. It was once thought that such harsh environments were inhospitable and incapable of supporting a variety of life. However, numerous culture-dependent and -independent studies revealed the presence of an extensive diversity of aerobic and anaerobic bacteria and archaea that survive and grow under these multiple harsh conditions. This diversity includes the halophilic alkalithermophiles, a novel group of polyextremophiles that require for growth and proliferation the multiple extremes of high salinity, alkaline pH, and elevated temperature. Life under these conditions undoubtedly involves the development of unique physiological characteristics, phenotypic properties, and adaptive mechanisms that enable control of membrane permeability, control of intracellular osmotic balance, and stability of the cell wall, intracellular proteins, and other cellular constituents. This minireview highlights the ecology and growth characteristics of the extremely halophilic alkalithermophiles that have been isolated thus far. Biochemical, metabolic, and physiological properties of the extremely halophilic alkalithermophiles are described, and their roles in resistance to the combined stressors of high salinity, alkaline pH, and high temperature are discussed. The isolation of halophilic alkalithermophiles broadens the physicochemical boundaries for life and extends the boundaries for the combinations of the maximum salinity, pH, and temperature that can support microbial growth. PMID:22492435

  15. Numerical Analysis of Flood modeling of upper Citarum River under Extreme Flood Condition

    Science.gov (United States)

    Siregar, R. I.

    2018-02-01

    This paper focuses on how to approach the numerical method and computation to analyse flood parameters. Water level and flood discharge are the flood parameters solved by numerical methods approach. Numerical method performed on this paper for unsteady flow conditions have strengths and weaknesses, among others easily applied to the following cases in which the boundary irregular flow. The study area is in upper Citarum Watershed, Bandung, West Java. This paper uses computation approach with Force2 programming and HEC-RAS to solve the flow problem in upper Citarum River, to investigate and forecast extreme flood condition. Numerical analysis based on extreme flood events that have occurred in the upper Citarum watershed. The result of water level parameter modeling and extreme flood discharge compared with measurement data to analyse validation. The inundation area about flood that happened in 2010 is about 75.26 square kilometres. Comparing two-method show that the FEM analysis with Force2 programs has the best approach to validation data with Nash Index is 0.84 and HEC-RAS that is 0.76 for water level. For discharge data Nash Index obtained the result analysis use Force2 is 0.80 and with use HEC-RAS is 0.79.

  16. A statistical methodology for the estimation of extreme wave conditions for offshore renewable applications

    DEFF Research Database (Denmark)

    Larsén, Xiaoli Guo; Kalogeri, Christina; Galanis, George

    2015-01-01

    and post-process outputs from a high resolution numerical wave modeling system for extreme wave estimation based on the significant wave height. This approach is demonstrated through the data analysis at a relatively deep water site, FINO 1, as well as a relatively shallow water area, coastal site Horns...... as a characteristic index of extreme wave conditions. The results from the proposed methodology seem to be in a good agreement with the measurements at both the relatively deep, open water and the shallow, coastal water sites, providing a potentially useful tool for offshore renewable energy applications. © 2015...... Rev, which is located in the North Sea, west of Denmark. The post-processing targets at correcting the modeled time series of the significant wave height, in order to match the statistics of the corresponding measurements, including not only the conventional parameters such as the mean and standard...

  17. Starch nanoparticles resulting from combination of dry heating under mildly acidic conditions and homogenization.

    Science.gov (United States)

    Kim, Jong Hun; Kim, Jiyeon; Park, Eun Young; Kim, Jong-Yea

    2017-07-15

    To modify starch granular structure, normal maize starch was subjected to dry heating with various amounts of 1.0M HCl (1.2, 1.4 or 1.6mL) and different treatment times (2, 4 or 8h). For all reaction conditions, at least 80% of the starch substance was recovered, and amylose and amylopectin B1 chains were preferentially cleaved. As acidic condition and/or treatment time increased, the treated granules were readily fragmented by homogenization. The treatment appeared to alter short-range crystalline structure (FT-IR), but long-range crystalline structure (XRD) remained intact. Homogenization for 60min fragmented the treated starch granules (subjected to reaction condition of 1.4mL/4h, 1.6mL/2h, and 1.6mL/4h) into nanoparticles consisting of individual platelet-like and spherical particles with diameters less than 100nm. However, the fragmentation caused obvious damage in the long-range crystalline structure of starch nanoparticles, while the short-range chain associations remained relatively intact. Copyright © 2017 Elsevier Ltd. All rights reserved.

  18. The myoglobin of Emperor penguin (Aptenodytes forsteri): amino acid sequence and functional adaptation to extreme conditions.

    Science.gov (United States)

    Tamburrini, M; Romano, M; Giardina, B; di Prisco, G

    1999-02-01

    In the framework of a study on molecular adaptations of the oxygen-transport and storage systems to extreme conditions in Antarctic marine organisms, we have investigated the structure/function relationship in Emperor penguin (Aptenodytes forsteri) myoglobin, in search of correlation with the bird life style. In contrast with previous reports, the revised amino acid sequence contains one additional residue and 15 differences. The oxygen-binding parameters seem well adapted to the diving behaviour of the penguin and to the environmental conditions of the Antarctic habitat. Addition of lactate has no major effect on myoglobin oxygenation over a large temperature range. Therefore, metabolic acidosis does not impair myoglobin function under conditions of prolonged physical effort, such as diving.

  19. Synthesis of Renewable Diesel Range Alkanes by Hydrodeoxygenation of Palmitic Acid over 5% Ni/CNTs under Mild Conditions

    Directory of Open Access Journals (Sweden)

    Yanan Duan

    2017-03-01

    Full Text Available Recently, the catalytic upgrading of bio-oil to renewable diesel has been attracting more and more attention. In the current paper, carbon nanotube (CNT-supported nickel catalysts, namely, 5% Ni/CNTs, were prepared for liquid hydrocarbon production through the deoxygenation of palmitic acid, the model compound of bio-oil under a mild condition of 240 °C reaction temperature and 2 MPa H2 pressure. The experimental results revealed that the main reaction product was pentadecane (yield of 89.64% at an optimum palmitic acid conversion of 97.25% via the hydrodecarbonylation (HDC process. The deoxygenation mechanism for palmitic acid conversion was also investigated. This study provides technical parameters and a theoretical basis for further industrialization in the bio-oil upgrading process.

  20. Necessary and sufficient conditions for big bangs, bounces, crunches, rips, sudden singularities and extremality events

    International Nuclear Information System (INIS)

    Cattoen, Celine; Visser, Matt

    2005-01-01

    Until recently, the physically relevant singularities occurring in FRW cosmologies had traditionally been thought to be limited to the 'big bang', and possibly a 'big crunch'. However, over the last few years, the zoo of cosmological singularities considered in the literature has become considerably more extensive, with 'big rips' and 'sudden singularities' added to the mix, as well as renewed interest in nonsingular cosmological events such as 'bounces' and 'turnarounds'. In this paper we present an extensive catalogue of such cosmological milestones, both at the kinematical and dynamical level. First, using generalized power series, purely kinematical definitions of these cosmological events are provided in terms of the behaviour of the scale factor a(t). The notion of a 'scale-factor singularity' is defined, and its relation to curvature singularities (polynomial and differential) is explored. Second, dynamical information is extracted by using the Friedmann equations (without assuming even the existence of any equation of state) to place constraints on whether or not the classical energy conditions are satisfied at the cosmological milestones. We use these considerations to derive necessary and sufficient conditions for the existence of cosmological milestones such as bangs, bounces, crunches, rips, sudden singularities and extremality events. Since the classification is extremely general and, modulo certain technical assumptions, is complete, the corresponding results are to a high degree model independent: in particular, we provide a characterization of the class of bangs, crunches and sudden singularities for which the dominant energy condition is satisfied

  1. Bridge Management Strategy Based on Extreme User Costs for Bridge Network Condition

    Directory of Open Access Journals (Sweden)

    Ladislaus Lwambuka

    2014-01-01

    Full Text Available This paper presents a practical approach for prioritization of bridge maintenance within a given bridge network. The maintenance prioritization is formulated as a multiobjective optimization problem where the simultaneous satisfaction of several conflicting objectives includes minimization of maintenance costs, maximization of bridge deck condition, and minimization of traffic disruption and associated user costs. The prevalence of user cost during maintenance period is twofold; the first case refers to the period of dry season where normally the traffic flow is diverted to alternative routes usually resurfaced to regain traffic access. The second prevalence refers to the absence of alternative routes which is often the case in the least developed countries; in this case the user cost referred to results from the waiting time while the traffic flow is put on hold awaiting accomplishment of the maintenance activity. This paper deals with the second scenario of traffic closure in the absence of alternative diversion routes which in essence results in extreme user cost. The paper shows that the multiobjective optimization approach remains valid for extreme cases of user costs in the absence of detour roads as often is the scenario in countries with extreme poor road infrastructure.

  2. Normal and Extreme Wind Conditions for Power at Coastal Locations in China.

    Science.gov (United States)

    Gao, Meng; Ning, Jicai; Wu, Xiaoqing

    2015-01-01

    In this paper, the normal and extreme wind conditions for power at 12 coastal locations along China's coastline were investigated. For this purpose, the daily meteorological data measured at the standard 10-m height above ground for periods of 40-62 years are statistically analyzed. The East Asian Monsoon that affects almost China's entire coastal region is considered as the leading factor determining wind energy resources. For most stations, the mean wind speed is higher in winter and lower in summer. Meanwhile, the wind direction analysis indicates that the prevalent winds in summer are southerly, while those in winter are northerly. The air densities at different coastal locations differ significantly, resulting in the difference in wind power density. The Weibull and lognormal distributions are applied to fit the yearly wind speeds. The lognormal distribution performs better than the Weibull distribution at 8 coastal stations according to two judgement criteria, the Kolmogorov-Smirnov test and absolute error (AE). Regarding the annual maximum extreme wind speed, the generalized extreme value (GEV) distribution performs better than the commonly-used Gumbel distribution. At these southeastern coastal locations, strong winds usually occur in typhoon season. These 4 coastal provinces, that is, Guangdong, Fujian, Hainan, and Zhejiang, which have abundant wind resources, are also prone to typhoon disasters.

  3. An archaeal tRNA-synthetase complex that enhances aminoacylation under extreme conditions

    DEFF Research Database (Denmark)

    Godinic-Mikulcic, Vlatka; Jaric, Jelena; Hausmann, Corinne D

    2011-01-01

    Aminoacyl-tRNA synthetases (aaRSs) play an integral role in protein synthesis, functioning to attach the correct amino acid with its cognate tRNA molecule. AaRSs are known to associate into higher-order multi-aminoacyl-tRNA synthetase complexes (MSC) involved in archaeal and eukaryotic translatio...... of a complex between MtSerRS and MtArgRS provides a means by which methanogenic archaea can optimize an early step in translation under a wide range of extreme environmental conditions....

  4. Proceedings of the first symposium on science of hadrons under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Chiba, Satoshi; Maruyama, Toshiki [eds.

    1999-08-01

    The first symposium on Science of Hadrons under Extreme Conditions, organized by the Research Group for Hadron Science, Advanced Science Research Center, was held at Tokai Research Establishment of JAERI on March 11 and 12, 1999. The symposium was devoted for discussions and presentations of research results in wide variety of fields such as observation of X-ray pulsars, theoretical studies of nuclear matter, nuclear structure, low- and high-energy nuclear reactions and QCD. Thirty seven papers on these topics presented at the symposium are indexed individually. (J.P.N.)

  5. Hydrolysis of dilute acid-pretreated cellulose under mild hydrothermal conditions.

    Science.gov (United States)

    Chimentão, R J; Lorente, E; Gispert-Guirado, F; Medina, F; López, F

    2014-10-13

    The hydrolysis of dilute acid-pretreated cellulose was investigated in a conventional oven and under microwave heating. Two acids--sulfuric and oxalic--were studied. For both hydrothermal conditions (oven and microwave) the resultant total organic carbon (TOC) values obtained by the hydrolysis of the cellulose pretreated with sulfuric acid were higher than those obtained by the hydrolysis of the cellulose pretreated with oxalic acid. However, the dicarboxylic acid exhibited higher hydrolytic efficiency towards glucose. The hydrolysis of cellulose was greatly promoted by microwave heating. The Rietveld method was applied to fit the X-ray patterns of the resultant cellulose after hydrolysis. Oxalic acid preferentially removed the amorphous region of the cellulose and left the crystalline region untouched. On the other hand, sulfuric acid treatment decreased the ordering of the cellulose by partially disrupting its crystalline structure. Copyright © 2014 Elsevier Ltd. All rights reserved.

  6. Controlled release of volatiles under mild reaction conditions: from nature to everyday products.

    Science.gov (United States)

    Herrmann, Andreas

    2007-01-01

    Volatile organic compounds serve in nature as semiochemicals for communication between species, and are often used as flavors and fragrances in our everyday life. The quite limited longevity of olfactive perception has led to the development of pro-perfumes or pro-fragrances--ideally nonvolatile and odorless fragrance precursors which release the active volatiles by bond cleavage. Only a limited amount of reaction conditions, such as hydrolysis, temperature changes, as well as the action of light, oxygen, enzymes, or microorganisms, can be used to liberate the many different chemical functionalities. This Review describes the controlled chemical release of fragrances and discusses additional challenges such as precursor stability during product storage as well as some aspects concerning toxicity and biodegradability. As the same systems can be applied in different areas of research, the scope of this Review covers fragrance delivery as well as the controlled release of volatiles in general.

  7. Enhanced photocatalytic degradation of pollutants in petroleum refinery wastewater under mild conditions

    International Nuclear Information System (INIS)

    Saien, J.; Nejati, H.

    2007-01-01

    A circulating photocatalytic reactor was used for removing aliphatic and aromatic organic pollutants in refinery wastewater. The TiO 2 added wastewater samples, while saturating with air, were irradiated with an immersed mercury UV lamp (400 W, 200-550 nm). Optimal catalyst concentration, fluid pH and temperature were obtained at amounts of near 100 mg L -1 , 3 and 318 K, respectively. A maximum reduction in chemical oxygen demand of more than 90% was achieved after about 4 h irradiation and hence, 73% after about only 90 min; significant pollutant removal was also achievable in the other conditions. The identification of the organic pollutants, provided by means of a GC/MS and a GC analysis systems, equipped with headspace injection technique, showed that the major compounds were different fractions of petroleum aliphatic hydrocarbons (up to C 10 ) and the well-known aromatic compounds such as benzene, toluene and ethylbenzene. The results showed a high efficiency degradation of all of these pollutants

  8. Enhanced photocatalytic degradation of pollutants in petroleum refinery wastewater under mild conditions

    Energy Technology Data Exchange (ETDEWEB)

    Saien, J. [Department of Applied Chemistry, University of Bu-Ali Sina, Hamadan 65174 (Iran, Islamic Republic of)], E-mail: saien@basu.ac.ir; Nejati, H. [Department of Applied Chemistry, University of Bu-Ali Sina, Hamadan 65174 (Iran, Islamic Republic of)

    2007-09-05

    A circulating photocatalytic reactor was used for removing aliphatic and aromatic organic pollutants in refinery wastewater. The TiO{sub 2} added wastewater samples, while saturating with air, were irradiated with an immersed mercury UV lamp (400 W, 200-550 nm). Optimal catalyst concentration, fluid pH and temperature were obtained at amounts of near 100 mg L{sup -1}, 3 and 318 K, respectively. A maximum reduction in chemical oxygen demand of more than 90% was achieved after about 4 h irradiation and hence, 73% after about only 90 min; significant pollutant removal was also achievable in the other conditions. The identification of the organic pollutants, provided by means of a GC/MS and a GC analysis systems, equipped with headspace injection technique, showed that the major compounds were different fractions of petroleum aliphatic hydrocarbons (up to C{sub 10}) and the well-known aromatic compounds such as benzene, toluene and ethylbenzene. The results showed a high efficiency degradation of all of these pollutants.

  9. Sustainable Synthesis of Oxalic and Succinic Acid through Aerobic Oxidation of C6 Polyols Under Mild Conditions.

    Science.gov (United States)

    Ventura, Maria; Williamson, David; Lobefaro, Francesco; Jones, Matthew D; Mattia, Davide; Nocito, Francesco; Aresta, Michele; Dibenedetto, Angela

    2018-03-22

    The sustainable chemical industry encompasses a shift from the use of fossil carbon to renewable carbon. The synthesis of chemicals from nonedible biomass (cellulosic or oil) represents one of the key steps for "greening" the chemical industry. In this paper, we report the aerobic oxidative cleavage of C6 polyols (5-HMF, glucose, fructose and sucrose) to oxalic acid (OA) and succinic acid (SA) in water under mild conditions using M@CNT and M@NCNT (M=Fe, V; CNT=carbon nanotubes; NCNT=N-doped CNT), which, under suitable conditions, were recoverable and reusable without any loss of efficiency. The influence of the temperature, O 2 pressure (PO2 ), reaction time and stirring rate are discussed and the best reaction conditions are determined for an almost complete conversion of the starting material and a good OA yield of 48 %. SA and formic acid were the only co-products. The former could be further converted into OA by oxidation in the presence of formic acid, resulting in an overall OA yield of >62 %. This process was clean and did not produce organic waste nor gas emissions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  10. Extreme Sea Conditions in Shallow Water: Estimation based on in-situ measurements

    Science.gov (United States)

    Le Crom, Izan; Saulnier, Jean-Baptiste

    2013-04-01

    The design of marine renewable energy devices and components is based, among others, on the assessment of the environmental extreme conditions (winds, currents, waves, and water level) that must be combined together in order to evaluate the maximal loads on a floating/fixed structure, and on the anchoring system over a determined return period. Measuring devices are generally deployed at sea over relatively short durations (a few months to a few years), typically when describing water free surface elevation, and extrapolation methods based on hindcast data (and therefore on wave simulation models) have to be used. How to combine, in a realistic way, the action of the different loads (winds and waves for instance) and which correlation of return periods should be used are highly topical issues. However, the assessment of the extreme condition itself remains a not-fully-solved, crucial, and sensitive task. Above all in shallow water, extreme wave height, Hmax, is the most significant contribution in the dimensioning process of EMR devices. As a case study, existing methodologies for deep water have been applied to SEMREV, the French marine energy test site. The interest of this study, especially at this location, goes beyond the simple application to SEMREV's WEC and floating wind turbines deployment as it could also be extended to the Banc de Guérande offshore wind farm that are planned close by. More generally to pipes and communication cables as it is a redundant problematic. The paper will first present the existing measurements (wave and wind on site), the prediction chain that has been developed via wave models, the extrapolation methods applied to hindcast data, and will try to formulate recommendations for improving this assessment in shallow water.

  11. Does red noise increase or decrease extinction risk? Single extreme events versus series of unfavorable conditions.

    Science.gov (United States)

    Schwager, Monika; Johst, Karin; Jeltsch, Florian

    2006-06-01

    Recent theoretical studies have shown contrasting effects of temporal correlation of environmental fluctuations (red noise) on the risk of population extinction. It is still debated whether and under which conditions red noise increases or decreases extinction risk compared with uncorrelated (white) noise. Here, we explain the opposing effects by introducing two features of red noise time series. On the one hand, positive autocorrelation increases the probability of series of poor environmental conditions, implying increasing extinction risk. On the other hand, for a given time period, the probability of at least one extremely bad year ("catastrophe") is reduced compared with white noise, implying decreasing extinction risk. Which of these two features determines extinction risk depends on the strength of environmental fluctuations and the sensitivity of population dynamics to these fluctuations. If extreme (catastrophic) events can occur (strong noise) or sensitivity is high (overcompensatory density dependence), then temporal correlation decreases extinction risk; otherwise, it increases it. Thus, our results provide a simple explanation for the contrasting previous findings and are a crucial step toward a general understanding of the effect of noise color on extinction risk.

  12. Studies in the statistical and thermal properties of hadronic matter under some extreme conditions

    International Nuclear Information System (INIS)

    Chase, K.C.; Mekjian, A.Z.; Bhattacharyya, P.

    1997-01-01

    The thermal and statistical properties of hadronic matter under some extreme conditions are investigated using an exactly solvable canonical ensemble model. A unified model describing both the fragmentation of nuclei and the thermal properties of hadronic matter is developed. Simple expressions are obtained for quantities such as the hadronic equation of state, specific heat, compressibility, entropy, and excitation energy as a function of temperature and density. These expressions encompass the fermionic aspect of nucleons, such as degeneracy pressure and Fermi energy at low temperatures and the ideal gas laws at high temperatures and low density. Expressions are developed which connect these two extremes with behavior that resembles an ideal Bose gas with its associated Bose condensation. In the thermodynamic limit, an infinite cluster exists below a certain critical condition in a manner similar to the sudden appearance of the infinite cluster in percolation theory. The importance of multiplicity fluctuations is discussed and some recent data from the EOS collaboration on critical point behavior of nuclei can be accounted for using simple expressions obtained from the model. copyright 1997 The American Physical Society

  13. Quantitative evaluation of the mitochondrial proteomes of Drosophila melanogaster adapted to extreme oxygen conditions.

    Directory of Open Access Journals (Sweden)

    Songyue Yin

    Full Text Available Mitochondria are the primary organelles that consume oxygen and provide energy for cellular activities. To investigate the mitochondrial mechanisms underlying adaptation to extreme oxygen conditions, we generated Drosophila strains that could survive in low- or high-oxygen environments (LOF or HOF, respectively, examined their mitochondria at the ultrastructural level via transmission electron microscopy, studied the activity of their respiratory chain complexes, and quantitatively analyzed the protein abundance responses of the mitochondrial proteomes using Isobaric tag for relative and absolute quantitation (iTRAQ. A total of 718 proteins were identified with high confidence, and 55 and 75 mitochondrial proteins displayed significant differences in abundance in LOF and HOF, respectively, compared with the control flies. Importantly, these differentially expressed mitochondrial proteins are primarily involved in respiration, calcium regulation, the oxidative response, and mitochondrial protein translation. A correlation analysis of the changes in the levels of the mRNAs corresponding to differentially regulated mitochondrial proteins revealed two sets of proteins with different modes of regulation (transcriptional vs. post-transcriptional in both LOF and HOF. We believe that these findings will not only enhance our understanding of the mechanisms underlying adaptation to extreme oxygen conditions in Drosophila but also provide a clue in studying human disease induced by altered oxygen tension in tissues and cells.

  14. Performance of PICS bags under extreme conditions in the sahel zone of Niger.

    Science.gov (United States)

    Baoua, Ibrahim B; Bakoye, Ousmane; Amadou, Laouali; Murdock, Larry L; Baributsa, Dieudonne

    2018-03-01

    Experiments in Niger assessed whether extreme environmental conditions including sunlight exposure affect the performance of triple-layer PICS bags in protecting cowpea grain against bruchids. Sets of PICS bags and woven polypropylene bags as controls containing 50 kg of naturally infested cowpea grain were held in the laboratory or outside with sun exposure for four and one-half months. PICS bags held either inside or outside exhibited no significant increase in insect damage and no loss in weight after 4.5 months of storage compared to the initial values. By contrast, woven bags stored inside or outside side by side with PICS bags showed several-fold increases in insects present in or on the grain and significant losses in grain weight. Grain stored inside in PICS bags showed no reduction in germination versus the initial value but there was a small but significant drop in germination of grain in PICS bags held outside (7.6%). Germination rates dropped substantially more in grain stored in woven bags inside (16.1%) and still more in woven bags stored outside (60%). PICS bags held inside and outside retained their ability to maintain internal reduced levels of oxygen and elevated levels of carbon dioxide. Exposure to extreme environmental conditions degraded the external polypropylene outer layer of the PICS triple-layer bag. Even so, the internal layers of polyethylene were more slowly degraded. The effects of exposure to sunlight, temperature and humidity variation within the sealed bags are described.

  15. Extreme Wave-Induced Oscillation in Paradip Port Under the Resonance Conditions

    Science.gov (United States)

    Kumar, Prashant; Gulshan

    2017-12-01

    A mathematical model is constructed to analyze the long wave-induced oscillation in Paradip Port, Odisha, India under the resonance conditions to avert any extreme wave hazards. Boundary element method (BEM) with corner contribution is utilized to solve the Helmholtz equation under the partial reflection boundary conditions. Furthermore, convergence analysis is also performed for the boundary element scheme with uniform and non-uniform discretization of the boundary. The numerical scheme is also validated with analytic approximation and existing studies based on harbor resonance. Then, the amplification factor is estimated at six key record stations in the Paradip Port with multidirectional incident waves and resonance modes are also estimated at the boundary of the port. Ocean surface wave field is predicted in the interior of Paradip Port for the different directional incident wave at various resonance modes. Moreover, the safe locations in the port have been identified for loading and unloading of moored ship with different resonance modes and directional incident waves.

  16. Influence of Extreme Storage Conditions on Extra Virgin Olive Oil Parameters: Traceability Study

    Directory of Open Access Journals (Sweden)

    Alfredo Escudero

    2016-01-01

    Full Text Available This study reflects the effect of extreme storage conditions on several extra virgin olive oil (EVOO varieties (arbequina, hojiblanca, and picual. The conditions were simulated in the laboratory, by means of heating treatments in stove at different temperatures (40 and 60°C and times (two and three weeks. The aim is the evaluation of the deterioration of the quality parameters and minority components, which are responsible for the nutritional and therapeutic properties (fatty acids, polyphenols, pigments, and tocopherols, and organoleptic qualities. The quality criteria and limits used in this work are according to International Olive Council. The results contribute to the control of the traSceability for the commercialization of the EVOO.

  17. Establishment and performance of an experimental green roof under extreme climatic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Klein, Petra M., E-mail: pkklein@ou.edu [School of Meteorology, University of Oklahoma, Norman, OK (United States); Coffman, Reid, E-mail: rcoffma4@kent.edu [College of Architecture and Environmental Design, Kent State University, Kent, OH (United States)

    2015-04-15

    Green roofs alter the surface energy balance and can help in mitigating urban heat islands. However, the cooling of green roofs due to evapotranspiration strongly depends on the climatic conditions, and vegetation type and density. In the Southern Central Plains of the United States, extreme weather events, such as high winds, heat waves and drought conditions pose challenges for successful implementation of green roofs, and likely alter their standard performance. The National Weather Center Experimental Green Roof, an interdisciplinary research site established in 2010 in Norman, OK, aimed to investigate the ecological performance and surface energy balance of green roof systems. Starting in May 2010, 26 months of vegetation studies were conducted and the radiation balance, air temperature, relative humidity, and buoyancy fluxes were monitored at two meteorological stations during April–October 2011. The establishment of a vegetative community trended towards prairie plant dominance. High mortality of succulents and low germination of grasses and herbaceous plants contributed to low vegetative coverage. In this condition succulent diversity declined. Bouteloua gracilis and Delosperma cooperi showed typological dominance in harsh climatic conditions, while Sedum species experienced high mortality. The plant community diversified through volunteers such as Euphorbia maculate and Portulaca maculate. Net radiation measured at a green-roof meteorological station was higher than at a control station over the original, light-colored roofing material. These findings indicate that the albedo of the green roof was lower than the albedo of the original roofing material. The low vegetative coverage during the heat and drought conditions in 2011, which resulted in the dark substrate used in the green roof containers being exposed, likely contributed to the low albedo values. Nevertheless, air temperatures and buoyancy fluxes were often lower over the green roof indicating

  18. Establishment and performance of an experimental green roof under extreme climatic conditions

    International Nuclear Information System (INIS)

    Klein, Petra M.; Coffman, Reid

    2015-01-01

    Green roofs alter the surface energy balance and can help in mitigating urban heat islands. However, the cooling of green roofs due to evapotranspiration strongly depends on the climatic conditions, and vegetation type and density. In the Southern Central Plains of the United States, extreme weather events, such as high winds, heat waves and drought conditions pose challenges for successful implementation of green roofs, and likely alter their standard performance. The National Weather Center Experimental Green Roof, an interdisciplinary research site established in 2010 in Norman, OK, aimed to investigate the ecological performance and surface energy balance of green roof systems. Starting in May 2010, 26 months of vegetation studies were conducted and the radiation balance, air temperature, relative humidity, and buoyancy fluxes were monitored at two meteorological stations during April–October 2011. The establishment of a vegetative community trended towards prairie plant dominance. High mortality of succulents and low germination of grasses and herbaceous plants contributed to low vegetative coverage. In this condition succulent diversity declined. Bouteloua gracilis and Delosperma cooperi showed typological dominance in harsh climatic conditions, while Sedum species experienced high mortality. The plant community diversified through volunteers such as Euphorbia maculate and Portulaca maculate. Net radiation measured at a green-roof meteorological station was higher than at a control station over the original, light-colored roofing material. These findings indicate that the albedo of the green roof was lower than the albedo of the original roofing material. The low vegetative coverage during the heat and drought conditions in 2011, which resulted in the dark substrate used in the green roof containers being exposed, likely contributed to the low albedo values. Nevertheless, air temperatures and buoyancy fluxes were often lower over the green roof indicating

  19. Diamonds on Diamond: structural studies at extreme conditions on the Diamond Light Source.

    Science.gov (United States)

    McMahon, M I

    2015-03-06

    Extreme conditions (EC) research investigates how the structures and physical and chemical properties of materials change when subjected to extremes of pressure and temperature. Pressures in excess of one million times atmospheric pressure can be achieved using a diamond anvil cell, and, in combination with high-energy, micro-focused radiation from a third-generation synchrotron such as Diamond, detailed structural information can be obtained using either powder or single-crystal diffraction techniques. Here, I summarize some of the research drivers behind international EC research, and then briefly describe the techniques by which high-quality diffraction data are obtained. I then highlight the breadth of EC research possible on Diamond by summarizing four examples from work conducted on the I15 and I19 beamlines, including a study which resulted in the first research paper from Diamond. Finally, I look to the future, and speculate as to the type of EC research might be conducted at Diamond over the next 10 years. © 2015 The Author(s) Published by the Royal Society. All rights reserved.

  20. Extreme summer temperatures in Iberia: health impacts and associated synoptic conditions

    Directory of Open Access Journals (Sweden)

    R. García-Herrera

    2005-02-01

    Full Text Available This paper examines the effect of extreme summer temperatures on daily mortality in two large cities of Iberia: Lisbon (Portugal and Madrid (Spain. Daily mortality and meteorological variables are analysed using the same methodology based on Box-Jenkins models. Results reveal that in both cases there is a triggering effect on mortality when maximum daily temperature exceeds a given threshold (34°C in Lisbon and 36°C in Madrid. The impact of most intense heat events is very similar for both cities, with significant mortality values occurring up to 3 days after the temperature threshold has been surpassed. This impact is measured as the percentual increase of mortality associated to a 1°C increase above the threshold temperature. In this respect, Lisbon shows a higher impact, 31%, as compared with Madrid at 21%. The difference can be attributed to demographic and socio-economic factors. Furthermore, the longer life span of Iberian women is critical to explain why, in both cities, females are more susceptible than males to heat effects, with an almost double mortality impact value.

    The analysis of Sea Level Pressure (SLP, 500hPa geopotential height and temperature fields reveals that, despite being relatively close to each other, Lisbon and Madrid have relatively different synoptic circulation anomalies associated with their respective extreme summer temperature days. The SLP field reveals higher anomalies for Lisbon, but extending over a smaller area. Extreme values in Madrid seem to require a more western location of the Azores High, embracing a greater area over Europe, even if it is not as deep as for Lisbon. The origin of the hot and dry air masses that usually lead to extreme heat days in both cities is located in Northern Africa. However, while Madrid maxima require wind blowing directly from the south, transporting heat from Southern Spain and Northern Africa, Lisbon maxima occur under more easterly

  1. Extreme summer temperatures in Iberia: health impacts and associated synoptic conditions

    Directory of Open Access Journals (Sweden)

    R. García-Herrera

    2005-02-01

    Full Text Available This paper examines the effect of extreme summer temperatures on daily mortality in two large cities of Iberia: Lisbon (Portugal and Madrid (Spain. Daily mortality and meteorological variables are analysed using the same methodology based on Box-Jenkins models. Results reveal that in both cases there is a triggering effect on mortality when maximum daily temperature exceeds a given threshold (34°C in Lisbon and 36°C in Madrid. The impact of most intense heat events is very similar for both cities, with significant mortality values occurring up to 3 days after the temperature threshold has been surpassed. This impact is measured as the percentual increase of mortality associated to a 1°C increase above the threshold temperature. In this respect, Lisbon shows a higher impact, 31%, as compared with Madrid at 21%. The difference can be attributed to demographic and socio-economic factors. Furthermore, the longer life span of Iberian women is critical to explain why, in both cities, females are more susceptible than males to heat effects, with an almost double mortality impact value. The analysis of Sea Level Pressure (SLP, 500hPa geopotential height and temperature fields reveals that, despite being relatively close to each other, Lisbon and Madrid have relatively different synoptic circulation anomalies associated with their respective extreme summer temperature days. The SLP field reveals higher anomalies for Lisbon, but extending over a smaller area. Extreme values in Madrid seem to require a more western location of the Azores High, embracing a greater area over Europe, even if it is not as deep as for Lisbon. The origin of the hot and dry air masses that usually lead to extreme heat days in both cities is located in Northern Africa. However, while Madrid maxima require wind blowing directly from the south, transporting heat from Southern Spain and Northern Africa, Lisbon maxima occur under more easterly conditions, when Northern African air

  2. Quadrupole beam-transport experiment for heavy ions under extreme space charge conditions

    International Nuclear Information System (INIS)

    Chupp, W.; Faltens, A.; Hartwig, E.C.

    1983-03-01

    A Cs ion-beam-transport experiment is in progress to study beam behavior under extreme space-charge conditions. A five-lens section matches the beam into a periodic electrostatic quadrupole FODO channel and its behavior is found to agree with predictions. With the available parameters (less than or equal to 200 keV, less than or equal to 20 mA, πepsilon/sub n/ greater than or equal to 10 - 7 π rad-m, up to 41 periods) the transverse (betatron) occillation frequency (nu) can be depressed down to one-tenth of its zero current value (nu/sub 0/), where nu/sup 2/ = nu/sub 0//sup 2/ -#betta#/sub p/ 2 /2, and #betta#/sub p/ is the beam plasma frequency. The current can be controlled by adjustment of the gun and the emittance can be controlled independently by means of a set of charged grids

  3. Development of a system for simultaneously generating triple extreme conditions for neutron scattering experiments

    Energy Technology Data Exchange (ETDEWEB)

    Ichimura, Shigeju [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1998-10-01

    We have developed new system available for controlling sample environment during the neutron scattering experiments. The system can simultaneously generate triple extreme conditions of low temperature, high magnetic field and high pressure. The system consists of : (1) a liquid-helium cryostat which enables the sample temperature range of 1.7 K to 200 K, (2) a superconducting magnet providing a vertical field up to 5 Tesla with antisymmetric split-coil geometry for polarized-beam experiments, and (3) a non-magnetic clamping high-pressure cell designed with the aim of generating hydrostatic pressure up to 2.5 Gpa. In the workshop, we will report the outline of the system and some results of performance tests using the system at JRR-3M of JAERI. (author)

  4. Foundations of high-energy-density physics physical processes of matter at extreme conditions

    CERN Document Server

    Larsen, Jon

    2017-01-01

    High-energy-density physics explores the dynamics of matter at extreme conditions. This encompasses temperatures and densities far greater than we experience on Earth. It applies to normal stars, exploding stars, active galaxies, and planetary interiors. High-energy-density matter is found on Earth in the explosion of nuclear weapons and in laboratories with high-powered lasers or pulsed-power machines. The physics explored in this book is the basis for large-scale simulation codes needed to interpret experimental results whether from astrophysical observations or laboratory-scale experiments. The key elements of high-energy-density physics covered are gas dynamics, ionization, thermal energy transport, and radiation transfer, intense electromagnetic waves, and their dynamical coupling. Implicit in this is a fundamental understanding of hydrodynamics, plasma physics, atomic physics, quantum mechanics, and electromagnetic theory. Beginning with a summary of the topics and exploring the major ones in depth, thi...

  5. Higher order magnetic modulation structures in rare earth metal, alloys and compounds under extreme conditions

    International Nuclear Information System (INIS)

    Kawano, S.

    2003-01-01

    Magnetic materials consisting of rare earth ions form modulation structures such as a helical or sinusoidal structure caused by the oscillating magnetic interaction between rare earth ions due to RKKY magnetic interaction. These modulation structures, in some cases, develop further to higher order modulation structures by additional modulations caused by higher order crystalline electric field, magnetic interactions such as spin-lattice interaction, external magnetic field and pressure. The higher order modulation structures are observed in a spin-slip structure or a helifan structure in Ho, and a tilt helix structure in a TbEr alloy. Paramagnetic ions originated from frustration generate many magnetic phases under applied external magnetic field. KUR neutron diffraction groups have performed the development and adjustment of high-pressure instruments and external magnetic fields for neutron diffraction spectrometers. The studies of 'neutron diffraction under extreme conditions' by the seven groups are described in this report. (Y. Kazumata)

  6. Recent studies of transplutonium compounds: new directions and use of extreme conditions

    International Nuclear Information System (INIS)

    Peterson, J.R.; Begun, G.M.; Gibson, J.K.

    1987-01-01

    The number of bulk-phase compounds prepared and characterized for each of the transplutonium (TPu) elements drops off precipitously with increasing atomic number. However, efforts have been made to increase the number of TPu compounds known and also the range of investigative methods applied to their characterization. The results of a worldwide survey to determine the status of the preparation of new TPu compounds and/or the application of new investigative techniques to the study of such compounds in bulk will be presented. The focus will then shift to Oak Ridge projects: extreme conditions of pressure and/or temperature are being used for synthesis and for absorption and raman spectral studies; single crystals of trihalides are being grown for spectral and magnetic studies; new ternary chalcogenide-halide compounds are being characterized; vaporization thermodynamics of TPu compounds are being determined; and attempts to stabilize unusual oxidation states are being carried out

  7. Offshore wind turbine risk quantification/evaluation under extreme environmental conditions

    International Nuclear Information System (INIS)

    Taflanidis, Alexandros A.; Loukogeorgaki, Eva; Angelides, Demos C.

    2013-01-01

    A simulation-based framework is discussed in this paper for quantification/evaluation of risk and development of automated risk assessment tools, focusing on applications to offshore wind turbines under extreme environmental conditions. The framework is founded on a probabilistic characterization of the uncertainty in the models for the excitation, the turbine and its performance. Risk is then quantified as the expected value of some risk consequence measure over the probability distributions considered for the uncertain model parameters. Stochastic simulation is proposed for the risk assessment, corresponding to the evaluation of some associated probabilistic integral quantifying risk, as it allows for the adoption of comprehensive computational models for describing the dynamic turbine behavior. For improvement of the computational efficiency, a surrogate modeling approach is introduced based on moving least squares response surface approximations. The assessment is also extended to a probabilistic sensitivity analysis that identifies the importance of each of the uncertain model parameters, i.e. risk factors, towards the total risk as well as towards each of the failure modes contributing to this risk. The versatility and computational efficiency of the advocated approaches is finally exploited to support the development of standalone risk assessment applets for automated implementation of the probabilistic risk quantification/assessment. -- Highlights: ► A simulation-based risk quantification/assessment framework is discussed. ► Focus is on offshore wind turbines under extreme environmental conditions. ► Approach is founded on probabilistic description of excitation/system model parameters. ► Surrogate modeling is adopted for improved computational efficiency. ► Standalone risk assessment applets for automated implementation are supported

  8. Comparison and development of advanced dosimetric techniques to be used under extreme climatic conditions

    International Nuclear Information System (INIS)

    Madhvanath, U.

    1975-08-01

    The post-irradiation fading characteristics of various dosimeters in function of relative humidity of air during storage were tested in specially set up humidity boxes. The temperature and relative humidity were varied between 5deg-35degC and 40-90%, respectively. Fading was 70% and 80% at 2 and 6 days respectively, for Kodak Type 2 film under 28degC and 76% relative humidity. Under these conditions the corresponding values for NTA emulsions were 30% and 80% respectively. Agfa-Gevaert films proved to be less sensitive and gave 20% and 30%, respectively, for the mentioned intervals. When Kodak Type 2 film was sealed in polythene bags, fading was reduced considerably, to appr. 15% in 4 weeks. Alternate storage of exposed films in humid and dry conditions also reduced fading to the same extent. When NTA emulsions were double-sealed with desiccant inside fading was reduced to 10% in 15 days. CaSO 4 :Dy (DRP and Harshaw) showed only 7% fading in 3 months. LiF TLD-100 was more sensitive, 13% in 2 months. Gamma-irradiated Li-borate has faded up to 30% at extreme climatic conditions in 3 months but thermal neutron irradiated Li-borate was resistant against fading for this period

  9. Aortic dissection: natural course of disease? Report of two cases representing the extremes of the condition

    International Nuclear Information System (INIS)

    Tollefsen, Isak; Joergensen, Ingrid K.; Woie, Leik; Fossdal, Jan E.

    2001-01-01

    Objective: In a time when diagnostic methods and above all, surgical as well as interventional radiological treatment for aortic aneurysms and aortic dissections have reached a point nobody could think of a few years back, the present authors feel that it is worth while to remind oneself of the natural course of disease in these conditions. Taking into consideration the high morbidity and mortality rate in surgically treated patients with aortic dissection, and the high complication rate per- and postoperatively, it also seems right to ask if a more expectative and conservative approach to the condition sometimes perhaps may be justified. Methods and material: Two case reports are given. One was a 15-year-old boy with Stanford (Daily) type B dissection who statistically ought to have a good prognosis, but who died within 2 h after onset of symptoms. The other patient, a middle-aged woman with Stanford type A dissection, survived for 25 years without operation. Conclusion: These two cases, though not unique viewed separately, we consider to represent the extremes of the condition and also a natural course of disease, while none of them was operated on

  10. Aortic dissection: natural course of disease? Report of two cases representing the extremes of the condition.

    Science.gov (United States)

    Tollefsen, I; Jørgensen, I K; Woie, L; Fossdal, J E

    2001-10-01

    In a time when diagnostic methods and above all, surgical as well as interventional radiological treatment for aortic aneurysms and aortic dissections have reached a point nobody could think of a few years back, the present authors feel that it is worth while to remind oneself of the natural course of disease in these conditions. Taking into consideration the high morbidity and mortality rate in surgically treated patients with aortic dissection, and the high complication rate per- and postoperatively, it also seems right to ask if a more expectative and conservative approach to the condition sometimes perhaps may be justified. Two case reports are given. One was a 15-year-old boy with Stanford (Daily) type B dissection who statistically ought to have a good prognosis, but who died within 2 h after onset of symptoms. The other patient, a middle-aged woman with Stanford type A dissection, survived for 25 years without operation. These two cases, though not unique viewed separately, we consider to represent the extremes of the condition and also a natural course of disease, while none of them was operated on.

  11. Establishment and performance of an experimental green roof under extreme climatic conditions.

    Science.gov (United States)

    Klein, Petra M; Coffman, Reid

    2015-04-15

    Green roofs alter the surface energy balance and can help in mitigating urban heat islands. However, the cooling of green roofs due to evapotranspiration strongly depends on the climatic conditions, and vegetation type and density. In the Southern Central Plains of the United States, extreme weather events, such as high winds, heat waves and drought conditions pose challenges for successful implementation of green roofs, and likely alter their standard performance. The National Weather Center Experimental Green Roof, an interdisciplinary research site established in 2010 in Norman, OK, aimed to investigate the ecological performance and surface energy balance of green roof systems. Starting in May 2010, 26 months of vegetation studies were conducted and the radiation balance, air temperature, relative humidity, and buoyancy fluxes were monitored at two meteorological stations during April-October 2011. The establishment of a vegetative community trended towards prairie plant dominance. High mortality of succulents and low germination of grasses and herbaceous plants contributed to low vegetative coverage. In this condition succulent diversity declined. Bouteloua gracilis and Delosperma cooperi showed typological dominance in harsh climatic conditions, while Sedum species experienced high mortality. The plant community diversified through volunteers such as Euphorbia maculate and Portulaca maculate. Net radiation measured at a green-roof meteorological station was higher than at a control station over the original, light-colored roofing material. These findings indicate that the albedo of the green roof was lower than the albedo of the original roofing material. The low vegetative coverage during the heat and drought conditions in 2011, which resulted in the dark substrate used in the green roof containers being exposed, likely contributed to the low albedo values. Nevertheless, air temperatures and buoyancy fluxes were often lower over the green roof indicating

  12. Deep desulfurization by amphiphilic lanthanide-containing polyoxometalates in ionic-liquid emulsion systems under mild conditions.

    Science.gov (United States)

    Xu, Junhua; Zhao, Shen; Ji, Yuanchun; Song, Yu-Fei

    2013-01-07

    Amphiphilic lanthanide-containing polyoxometalates (POMs) were prepared by surfactant encapsulation. Investigation of these lanthanide-containing POMs in oxidative desulfurization (ODS) showed that highly efficient deep desulfurization could be achieved in only 14 min with 100% conversion of dibenzothiophene under mild conditions by using (DDA)(9)LaW(10)/[omim]PF(6) (DDA=dimethyldioctadecylammonium, omim=1-octyl-3-methyl-imidazolium) in the presence of H(2) O(2) . Furthermore, deep desulfurization proceeds smoothly in model oil with an S content as low as 50 ppm. A scaled-up experiment in which the volume of model oil was increased from 5 to 1000 mL with S content of 1000 ppm indicated that about 99% sulfur removal can be achieved in 40 mins in an ionic-liquid emulsion system. To the best of our knowledge, the (DDA)(9)LaW(10)/[omim]PF(6) catalyst system with H(2)O(2) as oxidant is one of the most efficient desulfurization systems reported so far. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  13. Gold nanoclusters confined in a supercage of Y zeolite for aerobic oxidation of HMF under mild conditions.

    Science.gov (United States)

    Cai, Jiaying; Ma, Hong; Zhang, Junjie; Song, Qi; Du, Zhongtian; Huang, Yizheng; Xu, Jie

    2013-10-11

    Au nanoclusters with an average size of approximately 1 nm size supported on HY zeolite exhibit a superior catalytic performance for the selective oxidation of 5-hydroxymethyl-2-furfural (HMF) into 2,5-furandicarboxylic acid (FDCA). It achieved >99 % yield of 2,5-furandicarboxylic acid in water under mild conditions (60 °C, 0.3 MPa oxygen), which is much higher than that of Au supported on metal oxides/hydroxide (TiO2 , CeO2 , and Mg(OH)2 ) and channel-type zeolites (ZSM-5 and H-MOR). Detailed characterizations, such as X-ray diffraction, transmission electron microscopy, N2 -physisorption, and H2 -temperature-programmed reduction (TPR), revealed that the Au nanoclusters are well encapsulated in the HY zeolite supercage, which is considered to restrict and avoid further growing of the Au nanoclusters into large particles. The acidic hydroxyl groups of the supercage were proven to be responsible for the formation and stabilization of the gold nanoclusters. Moreover, the interaction between the hydroxyl groups in the supercage and the Au nanoclusters leads to electronic modification of the Au nanoparticles, which is supposed to contribute to the high efficiency in the catalytic oxidation of HMF to FDCA. Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  14. Palladium-pyridyl catalytic films: a highly active and recyclable catalyst for hydrogenation of styrene under mild conditions.

    Science.gov (United States)

    Gao, Shuiying; Li, Weijin; Cao, Rong

    2015-03-01

    Palladium-pyridyl catalytic films, (PdCl2/bpy)n, were created by alternating immersions of a substrate in PdCl2 and bpy (bpy=4, 4'-bipyridyl) solutions. The as-prepared (PdCl2/bpy)10 catalyst demonstrated a remarkable catalytic activity toward hydrogenation of styrene under mild conditions and the turnover frequency (TOF) is as high as 6944h(-1). Pd(II) ions of (PdCl2/bpy)n films are in situ reduced to Pd nanoparticles (NPs) during the hydrogenation of styrene process, which results in the catalytic activity of the films. The results of X-ray photoelectron spectroscopy (XPS) and transmission electron microscopy (TEM) further demonstrate that Pd(II) ions of (PdCl2/bpy)n films were gradually converted to Pd(0) states. The catalytic activity is related to bilayer numbers and the activity increases with the number of bilayers below 10 bilayers. The solid substrates coated with (PdCl2/bpy)n multilayer catalysts were easily removed from the reaction mixture without separation filtration. Moreover, (PdCl2/bpy)n catalysts were reused for 10 consecutive reactions without loss of activity. The present (PdCl2/bpy)n heterogeneous catalysts have the advantages of easy separation and good recyclability. Copyright © 2014 Elsevier Inc. All rights reserved.

  15. Functionalized MIL-101 with imidazolium-based ionic liquids for the cycloaddition of CO2 and epoxides under mild condition

    Science.gov (United States)

    Liu, Dan; Li, Gang; Liu, Haiou

    2018-01-01

    A kind of multi-functional sites metal-organic framework (MOF) composite (MIL-101-IMBr) was successfully prepared by post-synthesis modification of MIL-101 with imidazolium-based ionic liquids. The ionic liquids not only functionalize as basic sites but also provide halide anions, which serve as a nucleophile in cycloaddition reaction. The prepared functional MOF materials were characterized by X-ray diffraction, fourier transform infrared spectroscopy, scanning electron microscopy, energy dispersive spectroscopy, N2 adsorption-desorption and CO2 temperature programmed desorption. The results of fourier transform infrared spectroscopy and energy dispersive spectroscopy show that the MIL-101-IMBr composite was successfully synthesized. The N2 adsorption-desorption results clearly demonstrated that the modified composites still preserve high BET surface area and total pore volume. The composite exhibits high catalytic activity for the cycloaddition of CO2 with epoxides under mild and co-catalyst free conditions. The conversion of propylene oxide was 95.8% and the selectivity of cyclic carbonate was 97.6% under 0.8 MPa at 80 °C for 4 h. Moreover, the catalyst can be used for at least five times.

  16. A mild pulsed electric field condition that improves acid tolerance, growth, and protease activity of Lactobacillus acidophilus LA-K and Lactobacillus delbrueckii subspecies bulgaricus LB-12.

    Science.gov (United States)

    Najim, N; Aryana, Kayanush J

    2013-06-01

    Pulsed electric field (PEF) processing involves the application of pulses of voltage for less than 1 s to fluid products placed between 2 electrodes. The effect of mild PEF on beneficial characteristics of probiotic bacteria Lactobacillus acidophilus and Lactobacillus delbrueckii ssp. bulgaricus is not clearly understood. The objective of this study was to determine the influence of mild PEF conditions on acid tolerance, growth, and protease activity of Lb. acidophilus LA-K and Lactobacillus delbrueckii ssp. bulgaricus LB-12. A pilot plant PEF system (OSU-4M; The Ohio State University, Columbus) was used. The PEF treatments were positive square unipolar pulse width of 3 µs, pulse period of 0.5s, electric field strength of 1 kV/cm, delay time of 20 µs, flow rate of 60 mL/min, and 40.5°C PEF treatment temperature. Both Lb. acidophilus LA-K and Lb. bulgaricus LB-12 subjected to mild PEF conditions were acid tolerant until the end of the 120 min of incubation, unlike the Lb. bulgaricus control, which was not acid tolerant after 30 min. The mild PEF-treated Lb. acidophilus LA-K and Lb. bulgaricus LB-12 reached the logarithmic phase of growth an hour earlier than the control. Mild PEF conditions studied significantly improved acid tolerance, exponential growth, and protease activity of both Lb. acidophilus LA-K and Lb. bulgaricus LB-12 compared with the control. The mild PEF conditions studied can be recommended for pretreating cultures to enhance these desirable attributes. Copyright © 2013 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  17. A new fluorescent pH probe for extremely acidic conditions

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Yu [School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 (China); Taishan College, Shandong University, Jinan 250100 (China); Jiang, Zheng [School of Life Science, Shandong University, Jinan 250100 (China); Taishan College, Shandong University, Jinan 250100 (China); Xiao, Yu [School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 (China); Taishan College, Shandong University, Jinan 250100 (China); Bi, Fu-Zhen [School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 (China); Miao, Jun-Ying, E-mail: miaojy@sdu.edu.cn [School of Life Science, Shandong University, Jinan 250100 (China); Zhao, Bao-Xiang, E-mail: bxzhao@sdu.edu.cn [School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100 (China)

    2014-04-01

    A new coumarin-based fluorescent probe can detect highly acidic conditions in both solution and bacteria with high selectivity and sensitivity. Highlights: • A new fluorescence probe for very low pH was synthesized and characterized. • The probe can monitor pH in solution and bacteria. • The two-step protonation of N atoms of the probe leads to fluorescence quenching. Abstract: A novel turn-off fluorescent probe based on coumarin and imidazole moiety for extremely acidic conditions was designed and developed. The probe with pKa = 2.1 is able to respond to very low pH value (below 3.5) with high sensitivity relying on fluorescence quenching at 460 nm in fluorescence spectra or the ratios of absorbance maximum at 380 nm to that at 450 nm in UV–vis spectra. It can quantitatively detect pH value based on equilibrium equation, pH = pKa -log[(Ix - Ib)/(Ia - Ix)]. It had very short response time that was less than 1 min, good reversibility and nearly no interference from common metal ions. Moreover, using ¹H NMR analysis and theoretical calculation of molecular orbital, we verified that a two-step protonation process of two N atoms of the probe leaded to photoinduced electron transfer (PET), which was actually the mechanism of the fluorescence quenching phenomenon under strongly acidic conditions. Furthermore, the probe was also applied to imaging strong acidity in bacteria, E.coli and had good effect. This work illustrates that the new probe could be a practical and ideal pH indicator for strongly acidic conditions with good biological significance.

  18. Developmental Exposure to Mild Variable Stress: Adult Offspring Performance in Trace Fear Conditioning after Prenatal and Postnatal Stress

    Science.gov (United States)

    In utero exposure to mild variable stress has been reported to influence learning and memory formation in offspring. Our research aims to examine whether nonchemical environmental stressors will exacerbate effects to chemical exposure. This study utilized a varying stress parad...

  19. Measurement and analysis of polarization curves of mild steel in sodium carbonate/bicarbonate solution under erosion-corrosion conditions

    Energy Technology Data Exchange (ETDEWEB)

    Yuan, Q. [Taiyuan University of Technology, Taiyuan (China). Research Institute of Surface Engineering

    2002-06-01

    The polarization curves of mild steel in de-aerated 0.5 and mol NaHCO{sub 3} + 0.5 mol Na{sub 2}CO{sub 3} solution with and without erodent particles of 300 g/L of 100 {mu}m alumina have been measured using a rotating cylinder electrode (RCE) apparatus over the range of rotation speeds fro 0 to 4,000 r/min. The results show that the mild steel in the de-aerated slurry exhibits classical active/passive polarization behavior. The speed of cylinder rotation has a great effect in the presence of particles on the active dissolution current density. The erosion-corrosion process is severely erosion-dominated for the mild steel. However, the poor corrosion resistance of the mild steel in such turbulent slurries is also significant, especially at lower than 4 m/s. 19 refs., 5 figs.

  20. Regional metamorphism at extreme conditions: Implications for orogeny at convergent plate margins

    Science.gov (United States)

    Zheng, Yong-Fei; Chen, Ren-Xu

    2017-09-01

    Regional metamorphism at extreme conditions refers either to Alpine-type metamorphism at low geothermal gradients of geothermal gradients of >30 °C/km. Extreme pressures refer to those above the polymorphic transition of quartz to coesite, so that ultrahigh-pressure (UHP) eclogite-facies metamorphism occurs at mantle depths of >80 km. Extreme temperatures refer to those higher than 900 °C at crustal depths of ≤80 km, so that ultrahigh-temperature (UHT) granulite-facies metamorphism occurs at medium to high pressures. While crustal subduction at the low geothermal gradients results in blueschist-eclogite facies series without arc volcanism, heating of the thinned orogenic lithosphere brings about the high geothermal gradients for amphibolite-granulite facies series with abundant magmatism. Therefore, UHP metamorphic rocks result from cold lithospheric subduction to the mantle depths, whereas UHT metamorphic rocks are produced by hot underplating of the asthenospheric mantle at the crustal depths. Active continental rifting is developed on the thinned lithosphere in response to asthenospheric upwelling, and this tectonism is suggested as a feasible mechanism for regional granulite-facies metamorphism, with the maximum temperature depending on the extent to which the mantle lithosphere is thinned prior to the rifting. While lithospheric compression is associated with subduction metamorphism in accretionary and collisional orogens, the thinned orogenic lithosphere undergoes extension due to the asthenospheric upwelling to result in orogen-parallel rifting metamorphism and magmatism. Thus, the rifting metamorphism provides a complement to the subduction metamorphism and its operation marks the asthenospheric heating of the orogenic lithosphere. Because of the partial melting and melt extraction of the lower continental crust, contemporaneous granite-migmatite-granulite associations may serve as a petrological indicator of rifting orogeny that is superimposed on

  1. TYPHOID FEVER WITH FATAL OUTCOME IN PEOPLE WITH SEVERE TROPHOLOGICAL FAILURE IN EXTREME CONDITIONS

    Directory of Open Access Journals (Sweden)

    Yu. I. Lyashenko

    2017-01-01

    Full Text Available For purpose of clinical and morphological characterization of typhoid fever with fatal outcome was perform analysis of medical documentation as well as postmortem studies of internal tissues in 36men aged 21 to 34 years with severe body weight loss and in the conditions of combat stress in period from 1983 to 1985. The results of the study find a number of clinical and pathomorphological features of typhoid fever in patients with body weight deficiency that were in extreme conditions. Focal changes of the central nervous system were detected. The defeat of the respiratory system was characterized from the first days of the disease by bronchitis, and in the subsequent development of pneumonia, plevritis and empyema of the pleura. Majority of patients had symptoms of cardiovascular and renal failure. In died in the first week of the disease and in 2/3 parts – in a later period were combined with the symptoms of infectious-toxic encephalopathy and severe acute respiratory failure. All died had postmortem dystrophic changes of cardiomyocytes, and in patients had fatal outcome in 2–5 weeks – also focal or diffuse myocarditis. In a third of the patients who died, the disease was complicated by intestinal perforations. In a number of cases, peritonitis was a consequence of necrosis of mesenteric lymph nodes. In all patients with a fatal outcome, hemorrhagic (thrombohemorrhagic syndrome was diagnosed. A significant proportion of patients posthumously detected signs of sepsis and other complications, many of which could be the cause of death.

  2. Single-photon detector operating under extremely high background photon flux conditions

    International Nuclear Information System (INIS)

    Prochazka, Ivan; Sopko, Bruno; Blazej, Josef

    2009-01-01

    We are reporting our results in research and development in the field of avalanche semiconductor single-photon detectors and their application. Our goal was a development of a solid-state photon-counting detector capable of high-precision photon arrival time tagging in extremely harsh operating conditions. The background photon flux exceeding 10 9 photons per second hitting the detector active area should not avoid the useful signal detection and recognition on the signal level of units of photons per second. This is background photon flux about two orders of magnitude higher than what the conventional solid-state photon counters accept. The detection timing resolution should be better than 100 ps and the delay stability should be on picosecond level. We have developed and tested the active quenched and gated avalanche structure on silicon providing the required features in connection with the K14 detection chips. The detector is capable of gated operation under the conditions of background photon flux of 5x10 9 photons per second. The operational detector tolerates long term exposures to the input photon flux exceeding 10 15 photons (>1 mW) per second without damage.

  3. Predicting the solubility of gases in Nitrile Butadiene Rubber in extreme conditions using molecular simulation

    Science.gov (United States)

    Khawaja, Musab; Molinari, Nicola; Sutton, Adrian; Mostofi, Arash

    In the oil and gas industry, elastomer seals play an important role in protecting sensitive monitoring equipment from contamination by gases - a problem that is exacerbated by the high pressures and temperatures found down-hole. The ability to predict and prevent such permeative failure has proved elusive to-date. Nitrile butadiene rubber (NBR) is a common choice of elastomer for seals due to its resistance to heat and fuels. In the conditions found in the well it readily absorbs small molecular weight gases. How this behaviour changes quantitatively for different gases as a function of temperature and pressure is not well-understood. In this work a series of fully atomistic simulations are performed to understand the effect of extreme conditions on gas solubility in NBR. Widom particle insertion is used to compute solubilities. The importance of sampling and allowing structural relaxation upon compression are highlighted, and qualitatively reasonable trends reproduced. Finally, while at STP it has previously been shown that the solubility of CO2 is higher than that of He in NBR, we observe that under the right circumstances it is possible to reverse this trend.

  4. Hemoglobin system of Sparus aurata: Changes in fishes farmed under extreme conditions

    International Nuclear Information System (INIS)

    Campo, Salvatore; Nastasi, Giancarlo; D'Ascola, Angela; Campo, Giuseppe M.; Avenoso, Angela; Traina, Paola; Calatroni, Alberto; Burrascano, Emanuele; Ferlazzo, Alida; Lupidi, Giulio; Gabbianelli, Rosita; Falcioni, Giancarlo

    2008-01-01

    In order to gain more knowledge on the stress responses of gilhead seabream (Sparus aurata) under extreme conditions, this study investigated the functional properties of the hemoglobin system and globin gene expression under hypoxia and low salinity. The oxygen affinity for the two hemoglobin components present inside the S. aurata erythrocyte was practically identical as was the influence of protons and organic phosphates (Root effect). The quantification of S. aurata hemoglobin fractions performed by HPLC and the data on gene expression of globin chains assayed by PCR indicate that under hypoxia and low salinity there is a change in the ratio between the two different hemoglobin components. The result indicating that the distinct hemoglobins present in S. aurata erythrocyte have almost identical functional properties, does not explain the adaptive response (expression change) following exposure of the animal to hypoxia or low salinity on the basis of their function as oxygen transporter. We hypothesize that other parallel biological functions that the hemoglobin molecule is known to display within the erythrocyte are involved in adaptive molecular mechanisms. The autoxidation-reduction cycle of hemoglobin could be involved in the response to particular living conditions

  5. Superparamagnetic iron oxide coated on the surface of cellulose nanospheres for the rapid removal of textile dye under mild condition

    Energy Technology Data Exchange (ETDEWEB)

    Qin, Yunfeng [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, and College of Material Science and Engineering, Donghua University, Shanghai 201620 (China); Qin, Zongyi, E-mail: phqin@dhu.edu.cn [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, and College of Material Science and Engineering, Donghua University, Shanghai 201620 (China); Liu, Yannan; Cheng, Miao; Qian, Pengfei [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, and College of Material Science and Engineering, Donghua University, Shanghai 201620 (China); Wang, Qian, E-mail: drwangqian23@163.com [Department of Orthopaedics, Shanghai First People' s Hospital, Shanghai Jiaotong University, 100 Haining Road, Hongkou District, Shanghai 200080 (China); Zhu, Meifang [State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, and College of Material Science and Engineering, Donghua University, Shanghai 201620 (China)

    2015-12-01

    Graphical abstract: - Highlights: • Anchoring superparamagnetic iron oxide on the surface of cellulose nanospheres as magnetically recyclable nanocatalys. • Achieving highly efficient Fenton-like reaction on the surface of composite nanospheres for rapid removal of textile dye. • Reaching nearly 98.0% degradation of Navy blue within 5 min under mild condition. - Abstract: Magnetic composite nanoparticles (MNPs) were prepared by anchoring iron oxide (Fe{sub 3}O{sub 4}) on the surface of carboxyl cellulose nanospheres through a facile chemical co-precipitation method. The as-prepared MNPs were characterized by atomic force microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, wide-angle X-ray diffraction measurement, thermal gravity analysis and vibrating sample magnetometry. These MNPs were of a generally spherical shape with a narrow size distribution, and exhibited superparamagnetic behaviors with high saturation magnetization. High efficient removal of Navy blue in aqueous solution was demonstrated at room temperature in a Fenton-like system containing the MNPs and H{sub 2}O{sub 2}, which benefited from small particle size, large surface area, high chemical activity, and good dispersibility of the MNPs. The removal efficiency of Navy blue induced by the MNPs prepared at a weight ratio of cellulose to iron of 1:2 were 90.6% at the first minute of the degradation reaction, and 98.0% for 5 min. Furthermore, these MNPs could be efficiently recycled and reused by using an external magnetic field. The approach presented in this paper promotes the use of renewable natural resources as templates for the preparation and stabilization of various inorganic nanomaterials for the purpose of catalysis, magnetic resonance imaging, biomedical and other potential applications.

  6. 360⁰ -View of Quantum Theory and Ab Initio Simulation at Extreme Conditions: 2014 Sanibel Symposium

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Hai-Ping [Univ. of Florida, Gainesville, FL (United States)

    2016-09-02

    The Sanibel Symposium 2014 was held February 16-21, 2014, at the King and Prince, St. Simons Island, GA. It was successful in bringing condensed-matter physicists and quantum chemists together productively to drive the emergence of those specialties. The Symposium had a significant role in preparing a whole generation of quantum theorists. The 54th Sanibel meeting looked to the future in two ways. We had 360⁰-View sessions to honor the exceptional contributions of Rodney Bartlett (70), Bill Butler (70), Yngve Öhrn (80), Fritz Schaefer (70), and Malcolm Stocks (70). The work of these five has greatly impacted several generations of quantum chemists and condensed matter physicists. The “360⁰” is the sum of their ages. More significantly, it symbolizes a panoramic view of critical developments and accomplishments in theoretical and computational chemistry and physics oriented toward the future. Thus, two of the eight 360⁰-View sessions focused specifically on younger scientists. The 360⁰-View program was the major component of the 2014 Sanibel meeting. Another four sessions included a sub-symposium on ab initio Simulations at Extreme Conditions, with focus on getting past the barriers of present-day Born-Oppenheimer molecular dynamics by advances in finite-temperature density functional theory, orbital-free DFT, and new all-numerical approaches.

  7. Theoretical and experimental study of single particle tracking in extreme conditions: single photon imaging

    International Nuclear Information System (INIS)

    Cajgfinger, T.

    2012-10-01

    This manuscript presents my thesis on the high frame rate (500 frames / second) single-photon detector electron-bombarded CMOS (ebCMOS). The first section compares three ultra-sensitive detectors and their methods for improving photon sensitivity: the CMOS low noise (sCMOS), the electron-multiplying CCD (emCCD) with signal multiplication by pixel and the ebCMOS with amplification by applied electric field. The method developed to detect single photon impacts with intra-pixel resolution on the ebCMOS sensor is presented. The second section compares the localization accuracy of these detectors in extreme conditions of very low photon flux (<10 photons/frame). First the theoretical limit is calculated using the Cramer-Rao lower bound for significant parameter sets. An experimental comparison of the detectors is then described. The setup provides one or more point sources controlled in position, signal and background noise. The results allow a comparison of the experimental effectiveness, purity and localization accuracy. The last section describes two experiments with the ebCMOS camera. The first aims at tracking hundreds of quantum dots simultaneously at the Nanoptec center. The second focuses on the swimming of bacteria at the surface at the Joliot Curie Institute. The point sources tracking algorithm using single photons and the Kalman filter implementation developed for these experiments is also described. (author)

  8. Characterization of extremely low frequency magnetic fields from diesel, gasoline and hybrid cars under controlled conditions.

    Science.gov (United States)

    Hareuveny, Ronen; Sudan, Madhuri; Halgamuge, Malka N; Yaffe, Yoav; Tzabari, Yuval; Namir, Daniel; Kheifets, Leeka

    2015-01-30

    This study characterizes extremely low frequency (ELF) magnetic field (MF) levels in 10 car models. Extensive measurements were conducted in three diesel, four gasoline, and three hybrid cars, under similar controlled conditions and negligible background fields. Averaged over all four seats under various driving scenarios the fields were lowest in diesel cars (0.02 μT), higher for gasoline (0.04-0.05 μT) and highest in hybrids (0.06-0.09 μT), but all were in-line with daily exposures from other sources. Hybrid cars had the highest mean and 95th percentile MF levels, and an especially large percentage of measurements above 0.2 μT. These parameters were also higher for moving conditions compared to standing while idling or revving at 2500 RPM and higher still at 80 km/h compared to 40 km/h. Fields in non-hybrid cars were higher at the front seats, while in hybrid cars they were higher at the back seats, particularly the back right seat where 16%-69% of measurements were greater than 0.2 μT. As our results do not include low frequency fields (below 30 Hz) that might be generated by tire rotation, we suggest that net currents flowing through the cars' metallic chassis may be a possible source of MF. Larger surveys in standardized and well-described settings should be conducted with different types of vehicles and with spectral analysis of fields including lower frequencies due to magnetization of tires.

  9. Assessment extreme hydrometeorological conditions in the Gulf of Bothnia, the Baltic Sea

    Science.gov (United States)

    Dvornikov, Anton; Martyanov, Stanislav; Ryabchenko, Vladimir; Eremina, Tatjana; Isaev, Alexey; Sein, Dmitry

    2017-04-01

    Extreme hydrometeorological conditions in the Gulf of Bothnia, the Baltic Sea, are estimated paying a special attention to the area of the future construction of nuclear power plant (NPP) "Hanhikivi-1" (24° 16' E, 64° 32' N). To produce these estimates, long-term observations and results from numerical models of water and ice circulation and wind waves are used. It is estimated that the average annual air temperature in the vicinity of the station is +3° C, summer and winter extreme temperature is equal to 33.3° C and -41.5° C, respectively. Model calculations of wind waves have shown that the most dangerous (in terms of the generation of wind waves in the NPP area) is a north-west wind with the direction of 310°. The maximum height of the waves in the Gulf of Bothnia near the NPP for this wind direction with wind velocity of 10 m/s is 1.2-1.4 m. According to the model estimates, the highest possible level of the sea near the NPP is 248 cm, the minimum level, -151 cm, respectively for the western and eastern winds. These estimates are in good agreement with observations on the sea level for the period 1922-2015 at the nearest hydrometeorological station Raahe (Finland). In order to assess the likely impact of the NPP on the marine environment numerical experiments for the cold (2010) and warm year (2014) have been carried out. These calculations have shown that permanent release of heat into the marine environment from the operating NPP for the cold year (2010) will increase the temperature in the upper layer of 0-250m zone by 10°C in winter - spring and by 8°C in summer - early autumn, and in the bottom layer of 0-250m zone by 5°C in winter - spring and 3°C in summer - early autumn. For the warm year (2014), these temperature changes are smaller. Ice cover in both cases will disappear in two - kilometer vicinity of the NPP. These effects should be taken into account when assessing local climate changes in the future

  10. A combination of extreme environmental conditions favor the prevalence of Endospore-forming Firmicutes

    Directory of Open Access Journals (Sweden)

    Sevasti Filippidou

    2016-11-01

    Full Text Available Environmental conditions unsuitable for microbial growth are the rule rather than the exception in most habitats. In response to this, microorganisms have developed various strategies to withstand environmental conditions that limit active growth. Endospore-forming Firmicutes (EFF deploy a myriad of survival strategies in order to resist adverse conditions. Like many bacterial groups, they can form biofilms and detect nutrient scarcity through chemotaxis. Moreover, within this paraphyletic group of Firmicutes, ecophysiological optima are diverse. Nonetheless, a response to adversity that delimits this group is the formation of wet-heat resistant spores. These strategies are energetically demanding and therefore might affect the biological success of EFF. Therefore, we hypothesize that abundance and diversity of EFF should be maximized in those environments in which the benefits of these survival strategies offsets the energetic cost. In order to address this hypothesis, geothermal and mineral springs and drillings were selected because in these environments of steep physicochemical gradients, diversified survival strategies may become a successful strategy. We collected 71 samples from geothermal and mineral environments characterized by none (null, single or multiple limiting environmental factors (temperature, pH, UV radiation and specific mineral composition. To measure success, we quantified EFF gene copy numbers (GCN; spo0A gene in relation to total bacterial GCN (16S rRNA gene, as well as the contribution of EFF to community composition. The quantification showed that relative GCN for EFF reached up to 20% at sites characterized by multiple limiting environmental factors, whereas it corresponded to less than 1% at sites with one or no limiting environmental factor. Pyrosequencing of the 16S rRNA gene supports a higher contribution of EFF at sites with multiple limiting factors. Community composition suggested a combination of phylotypes

  11. XBeach-G: a tool for predicting gravel barrier response to extreme storm conditions

    Science.gov (United States)

    Masselink, Gerd; Poate, Tim; McCall, Robert; Roelvink, Dano; Russell, Paul; Davidson, Mark

    2014-05-01

    Gravel beaches protect low-lying back-barrier regions from flooding during storm events and their importance to society is widely acknowledged. Unfortunately, breaching and extensive storm damage has occurred at many gravel sites and this is likely to increase as a result of sea-level rise and enhanced storminess due to climate change. Limited scientific guidance is currently available to provide beach managers with operational management tools to predict the response of gravel beaches to storms. The New Understanding and Prediction of Storm Impacts on Gravel beaches (NUPSIG) project aims to improve our understanding of storm impacts on gravel coastal environments and to develop a predictive capability by modelling these impacts. The NUPSIG project uses a 5-pronged approach to address its aim: (1) analyse hydrodynamic data collected during a proto-type laboratory experiment on a gravel beach; (2) collect hydrodynamic field data on a gravel beach under a range of conditions, including storm waves with wave heights up to 3 m; (3) measure swash dynamics and beach response on 10 gravel beaches during extreme wave conditions with wave heights in excess of 3 m; (4) use the data collected under 1-3 to develop and validate a numerical model to model hydrodynamics and morphological response of gravel beaches under storm conditions; and (5) develop a tool for end-users, based on the model formulated under (4), for predicting storm response of gravel beaches and barriers. The aim of this presentation is to present the key results of the NUPSIG project and introduce the end-user tool for predicting storm response on gravel beaches. The model is based on the numerical model XBeach, and different forcing scenarios (wave and tides), barrier configurations (dimensions) and sediment characteristics are easily uploaded for model simulations using a Graphics User Interface (GUI). The model can be used to determine the vulnerability of gravel barriers to storm events, but can also be

  12. Chemical constraints governing the origin of metabolism: the thermodynamic landscape of carbon group transformations under mild aqueous conditions

    Science.gov (United States)

    Weber, Arthur L.

    2002-01-01

    The thermodynamics of organic chemistry under mild aqueous conditions was examined in order to begin to understand its influence on the structure and operation of metabolism and its antecedents. Free energies (deltaG) were estimated for four types of reactions of biochemical importance carbon-carbon bond cleavage and synthesis, hydrogen transfer between carbon groups, dehydration of alcohol groups, and aldo-keto isomerization. The energies were calculated for mainly aliphatic groups composed of carbon, hydrogen, and oxygen. The energy values showed (1) that generally when carbon-carbon bond cleavage involves groups from different functional group classes (i.e., carboxylic acids, carbonyl groups, alcohols, and hydrocarbons), the transfer of the shared electron-pair to the more reduced carbon group is energetically favored over transfer to the more oxidized carbon group, and (2) that the energy of carbon-carbon bond transformation is primarily determined by the functional group class of the group that changes oxidation state in the reaction (i.e., the functional group class of the group that donates the shared electron-pair during cleavage, or that accepts the incipient shared electron-pair during synthesis). In contrast, the energy of hydrogen transfer between carbon groups is determined by the functional group class of both the hydrogen-donor group and the hydrogen-acceptor group. From these and other observations we concluded that the chemistry involved in the origin of metabolism (and to a lesser degree modern metabolism) was strongly constrained by (1) the limited redox-based transformation energy of organic substrates that is readily dissipated in a few energetically favorable irreversible reactions; (2) the energy dominance of a few transformation half-reactions that determines whether carbon-carbon bond transformation (cleavage or synthesis) is energetically favorable (deltaG +3.5 kcal/mol); and (3) the dependence of carbon group transformation energy on the

  13. Evolution of self-organization in nano-structured PVD coatings under extreme tribological conditions

    Energy Technology Data Exchange (ETDEWEB)

    Fox-Rabinovich, G., E-mail: gfox@mcmaster.ca [Department of Mechanical Engineering, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L7 (Canada); Kovalev, A. [Surface Phenomena Researches Group, CNIICHERMET, 9/23, 2-nd Baumanskaya Street, Moscow 105005 (Russian Federation); Aguirre, M.H. [Laboratory of Advanced Microscopy, Institute of Nanoscience of Aragón, University of Zaragoza, 50018 Zaragoza (Spain); Yamamoto, K. [Materials Research Laboratory, Kobe Steel Ltd, 1-5-5 Takatsuda-dai, Nishi-ku, Kobe 651-2271, Hyogo (Japan); Veldhuis, S. [Department of Mechanical Engineering, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L7 (Canada); Gershman, I. [All-Russian Railway Research Institute, 10 Third Mytishchinskaya Street, Moscow 29851 (Russian Federation); Rashkovskiy, A. [Surface Phenomena Researches Group, CNIICHERMET, 9/23, 2-nd Baumanskaya Street, Moscow 105005 (Russian Federation); Endrino, J.L. [Albengoa Research, Energia Solar 1, Palmas Altas, Seville 41014 (Spain); Beake, B. [Micro Materials Limited, Willow House, Yale Business Village, Ellice Way, Wrexham LL13 7YL (United Kingdom); Dosbaeva, G. [Department of Mechanical Engineering, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L7 (Canada); Wainstein, D. [Surface Phenomena Researches Group, CNIICHERMET, 9/23, 2-nd Baumanskaya Street, Moscow 105005 (Russian Federation); Yuan, Junifeng; Bunting, J.W. [Department of Mechanical Engineering, McMaster University, 1280 Main St. W., Hamilton, ON, Canada L8S 4L7 (Canada)

    2014-04-01

    Highlights: • The evolution of self-organization under extreme frictional conditions has been studied. • Comprehensive characterization of the tribo-films was made using various surface analytical techniques. • During the running-in stage, mullite tribo-ceramics predominate on the surface of the nano-multilayer coating, establishing a functional hierarchy within the layer of tribo-films. • It is possible to control tribo-film evolution during self-organization by means of an increase in structural complexity and the non-equilibrium state of the surface engineered layer. - Abstract: The evolution of the self-organization process where dissipative structures are formed under the extreme frictional conditions associated with high performance dry machining of hardened steels has been studied in detail. The emphasis was on the progressive studies of surface transformations within multilayer and monolayer TiAlCrSiYN-based PVD coatings during the running-in stage of wear when self-organization process occurs. The coating layer was characterized by high resolution electron energy-loss spectroscopy (HREELS). It is shown that the nano-multilayer coating possesses higher non-equilibrium structure in comparison to the monolayer. Comprehensive studies of the tribo-films (dissipative structures) formed on the friction surface were made using a number of advanced surface characterization techniques such as X-ray photoelectron spectroscopy (XPS) and X-ray absorption near edge structure (XANES). The data obtained for the tribo-films was combined with the detailed TEM studies of the structural and phase transformations within the underlying coating layer. This data was related to the micro-mechanical characteristics of the coating layer and its wear resistance. It was demonstrated that the evolution of the self-organization process is strongly controlled by the characteristics of the tribo-films formed at different stages of the wear process. Within running-in stage (after

  14. Overnight storage of whole blood: cooling and transporting blood at room temperature under extreme temperature conditions.

    Science.gov (United States)

    Thibault, L; Beauséjour, A; Jacques, A; Ducas, E; Tremblay, M

    2014-02-01

    Many countries allow the overnight storage of whole blood (WB) at ambient temperature. Some countries, such as Canada, also require a rapid cooling of WB with an active cooling system. Given the significant operational constraints associated with current cooling systems, an alternative method for cooling and transporting WB at 20-24°C was evaluated. Phase 22 cooling packs (TCP Reliable Inc., USA) were used in combination with vacuum-insulated panel (VIP) boxes. Temperature profiles of simulated WB units were studied in extreme temperatures (-35 and 40°C). The quality of blood components prepared using Phase 22 packs and CompoCool-WB (Fresenius HemoCare, Germany) was studied. Phase 22 packs reduced the temperature of simulated WB bags from 37 to 24°C in 1·7 ± 0·2 h. Used in combination with VIP boxes, Phase 22 packs maintain the temperature of bags between 20 and 24°C for 15 and 24 h, compared to 2 and 11 h with CompoCool-WB, when exposed at -35 and 40°C, respectively. The quality of platelet concentrates and plasma was comparable, regardless of the cooling system used. For red blood cell units, per cent haemolysis on day 42 was slightly higher in products prepared after cooling with Phase 22 packs compared to CompoCool-WB (0·33 ± 0·15% vs. 0·21 ± 0·06%; P environmental conditions. © 2013 International Society of Blood Transfusion.

  15. Complex layered dental restorations: Are they recognizable and do they survive extreme conditions?

    Science.gov (United States)

    Soon, Alistair S; Bush, Mary A; Bush, Peter J

    2015-09-01

    Recent research has shown that restorative dental materials can be recognized by microscopy and elemental analysis (scanning electron microscopy/energy dispersive X-ray spectroscopy and X-ray fluorescence; SEM/EDS and XRF) and that this is possible even in extreme conditions, such as cremation. These analytical methods and databases of dental materials properties have proven useful in DVI (disaster victim identification) of a commercial plane crash in 2009, and in a number of other victim identification cases. Dental materials appear on the market with ever expanding frequency. With their advent, newer methods of restoration have been proposed and adopted in the dental office. Methods might include placing multiple layers of dental materials, where they have different properties including adhesion, viscosity, or working time. These different dental materials include filled adhesives, flowable resins, glass ionomer cements, composite resins, liners and sealants. With possible combinations of different materials in these restorations, the forensic odontologist is now confronted with a new difficulty; how to recognize each individual material. The question might be posed if it is even possible to perform this task. Furthermore, an odontologist might be called upon to identify a victim under difficult circumstances, such as when presented with fragmented or incinerated remains. In these circumstances the ability to identify specific dental materials could assist in the identification of the deceased. Key to use of this information is whether these new materials and methods are detailed in the dental chart. Visual or radiographic inspection may not reveal the presence of a restoration, let alone the possible complex nature of that restoration. This study demonstrates another scientific method in forensic dental identification. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  16. An Invariant-Preserving ALE Method for Solids under Extreme Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Sambasivan, Shiv Kumar [Los Alamos National Laboratory; Christon, Mark A [Los Alamos National Laboratory

    2012-07-17

    We are proposing a fundamentally new approach to ALE methods for solids undergoing large deformation due to extreme loading conditions. Our approach is based on a physically-motivated and mathematically rigorous construction of the underlying Lagrangian method, vector/tensor reconstruction, remapping, and interface reconstruction. It is transformational because it deviates dramatically from traditionally accepted ALE methods and provides the following set of unique attributes: (1) a three-dimensional, finite volume, cell-centered ALE framework with advanced hypo-/hyper-elasto-plastic constitutive theories for solids; (2) a new physically and mathematically consistent reconstruction method for vector/tensor fields; (3) advanced invariant-preserving remapping algorithm for vector/tensor quantities; (4) moment-of-fluid (MoF) interface reconstruction technique for multi-material problems with solids undergoing large deformations. This work brings together many new concepts, that in combination with emergent cell-centered Lagrangian hydrodynamics methods will produce a cutting-edge ALE capability and define a new state-of-the-art. Many ideas in this work are new, completely unexplored, and hence high risk. The proposed research and the resulting algorithms will be of immediate use in Eulerian, Lagrangian and ALE codes under the ASC program at the lab. In addition, the research on invariant preserving reconstruction/remap of tensor quantities is of direct interest to ongoing CASL and climate modeling efforts at LANL. The application space impacted by this work includes Inertial Confinement Fusion (ICF), Z-pinch, munition-target interactions, geological impact dynamics, shock processing of powders and shaped charges. The ALE framework will also provide a suitable test-bed for rapid development and assessment of hypo-/hyper-elasto-plastic constitutive theories. Today, there are no invariant-preserving ALE algorithms for treating solids with large deformations. Therefore

  17. PREFACE: International Symposium on Molecular Conductors: Novel Functions of Molecular Conductors under Extreme Conditions (ISMC 2008)

    Science.gov (United States)

    Takahashi, Toshihiro; Suzumura, Yoshikazu

    2008-02-01

    The International Symposium on Molecular Conductors 2008 (ISMC2008) was held as the second international symposium of the project entitled `Novel Functions of Molecular Conductors under Extreme Conditions', which was supported by the Grant-in-aid for Scientific Research on Priority Areas from the Ministry of Education, Culture, Sports, Science and Technology in Japan. The project lasted from September 2003 to March 2008, and was completed by this symposium held at Okazaki Conference Center, Institute for Molecular Science, Okazaki, Japan (23-25 July 2008), which about 100 scientists attended. During the symposium, five project teams gave summary talks and exciting talks were given on the topics developed recently not only by the members of the project but also by other scientists including invited speakers from abroad, who are doing active research on molecular conductors. It is expected that papers presented in the symposium will give valuable hints for the next step in the research of this field. Therefore the organizers of this symposium decided to publish this proceedings in order to demonstrate these activities, not only for the local community of the project, but also for the broad society of international scientists who are interested in molecular conductors. The editors, who are also the organizers of this symposium, believe that this proceedings provides a significant and relevant contribution to the field of molecular conductors since it is the first time we have published such a proceedings as an electronic journal. We note that all papers published in this volume of Journal of Physics: Conference Series have been peer reviewed by expert referees. Editors made every effort to satisfy the criterion of a proceedings journal published by IOP Publishing. Toshihiro Takahashi and Yoshikazu Suzumura Editors: Toshihiro Takahashi (Gakushuin University) (Chairman) Kazushi Kanoda (University of Tokyo) Seiichi Kagoshima (University of Tokyo) Takehiko Mori (Tokyo

  18. Atmospheric conditions associated with extreme fire activity in the Western Mediterranean region.

    Science.gov (United States)

    Amraoui, Malik; Pereira, Mário G; DaCamara, Carlos C; Calado, Teresa J

    2015-08-15

    Active fire information provided by TERRA and AQUA instruments on-board sun-synchronous polar MODIS platform is used to describe fire activity in the Western Mediterranean and to identify and characterize the synoptic patterns of several meteorological fields associated with the occurrence of extreme fire activity episodes (EEs). The spatial distribution of the fire pixels during the period of 2003-2012 leads to the identification of two most affected sub-regions, namely the Northern and Western parts of the Iberian Peninsula (NWIP) and Northern Africa (NAFR). The temporal distribution of the fire pixels in these two sub-regions is characterized by: (i) high and non-concurrent inter- and intra-annual variability with maximum values during the summer of 2003 and 2005 in NWIP and 2007 and 2012 in NAFR; and, (ii) high intra-annual variability dominated by a prominent annual cycle with a main peak centred in August in both sub-regions and a less pronounced secondary peak in March only evident in NWIP region. The 34 EEs identified were grouped according to the location, period of occurrence and spatial configuration of the associated synoptic patterns into 3 clusters (NWIP-summer, NWIP-winter and NAFR-summer). Results from the composite analysis reveal similar fire weather conditions (statistically significant positive anomalies of air temperature and negative anomalies of air relative humidity) but associated with different circulation patterns at lower and mid-levels of the atmosphere associated with the occurrence of EEs in each cluster of the Western Mediterranean region. Copyright © 2015 Elsevier B.V. All rights reserved.

  19. The extreme condition analyzing for NEMPI shielding of electronic system in high-intensity pulsed radiation diagnosing

    International Nuclear Information System (INIS)

    Cheng Xiaolei; Liu Fang; Ouyang Xiaoping

    2012-01-01

    The difficulty for estimating the NEMPI (electromagnetic pulsed interference caused by the nuclear reaction) on the electronic system in high-intensity pulsed radiation diagnosing is analyzed in this article. To solve the difficulty, a method called 'Extreme Condition Analyzing' is presented for estimating the NEMPI conservatively and reliably. Through an extreme condition hypothesizing which could be described as 'Entire Coupling of Electric Field Energy', the E max (maximum electric field intensity which could be endured by the electronic system in the high-intensity pulsed radiation) could be figured out without any other information of the EMP caused by the nuclear reaction. Then a feasibility inspection is introduced, to confirm that the EMPI shielding request according to E max is not too extreme to be achieved. (authors)

  20. Safety analysis of spent fuel transport and storage casks under extreme impact conditions

    International Nuclear Information System (INIS)

    Wolff, D.; Wieser, G.; Ballheimer, V.; Voelzke, H.; Droste, B.

    2005-01-01

    Full text: Worldwide the security of transport and storage of spent fuel with respect to terrorism threats is a matter of concern. In Germany a spent nuclear fuel management program was developed by the government including a new concept of dry on-site interim storage instead of centralized interim storage. In order to minimize transports of spent fuel casks between nuclear power plants, reprocessing plants and central storage facilities, the operators of NPPs have to erect and to use interim storage facilities for spent nuclear fuel on the site or in the vicinity of nuclear power plants. Up to now, 11 on-site interim storage buildings, one storage tunnel and 4 on-site interim storage areas (preliminary cask storage till the on-site interim storage building is completed) have been licensed at 12 nuclear power plant sites. Inside the interim storage buildings the casks are kept in upright position, whereas at the preliminary interim storage areas horizontal storage of the casks on concrete slabs is used and each cask is covered by concrete elements. Storage buildings and concrete elements are designed only for gamma and neutron radiation shielding reasons and as weather protection. Therefore the security of spent fuel inside a dual purpose transport and storage cask depends on the inherent safety of the cask itself. For nearly three decades BAM has been investigating cask safety under severe accident conditions like drop tests from more than 9 m onto different targets and without impact limiters as well as artificially damaged prototype casks. Since the terror attacks of 11 September 2001 the determination of casks' inherent safety also under extreme impact conditions due to terrorist attacks has been of our increasing interest. With respect to spent fuel storage one of the most critical scenarios of a terrorist attack for a cask is the centric impact of a dynamic load onto the lid-seal-system caused e.g. by direct aircraft crash or its engine as well as by a

  1. Preparation, characterization and environmental/electrochemical energy storage testing of low-cost biochar from natural chitin obtained via pyrolysis at mild conditions

    Science.gov (United States)

    Magnacca, Giuliana; Guerretta, Federico; Vizintin, Alen; Benzi, Paola; Valsania, Maria C.; Nisticò, Roberto

    2018-01-01

    Chitin (a biopolymer obtained from shellfish industry) was used as precursor for the production of biochars obtained via pyrolysis treatments performed at mild conditions (in the 290-540 °C range). Biochars were physicochemical characterized in order to evaluate the pyrolysis-induced effects in terms of both functional groups and material structure. Moreover, such carbonaceous materials were tested as adsorbent substrates for the removal of target molecules from aqueous environment as well as in solid-gas experiments, to measure the adsorption capacities and selectivity toward CO2. Lastly, biochars were also investigated as possible cathode materials in sustainable and low-cost electrochemical energy storage devices, such as lithium-sulphur (Li-S) batteries. Interestingly, experimental results evidenced that such chitin-derived biochars obtained via pyrolysis at mild conditions are sustainable, low-cost and easy scalable alternative materials suitable for both environmental and energetic applications.

  2. Extreme conditioning programs and injury risk in a US Army Brigade Combat Team.

    Science.gov (United States)

    Grier, Tyson; Canham-Chervak, Michelle; McNulty, Vancil; Jones, Bruce H

    2013-01-01

    Brigades and battalions throughout the US Army are currently implementing a variety of exercise and conditioning programs with greater focus on preparation for mission-specific tasks. An Army physical therapy clinic working with a light infantry brigade developed the Advanced Tactical Athlete Conditioning (ATAC) program. The ATAC program is a unique physical training program consisting of high-intensity aquatic exercises, tactical agility circuits, combat core conditioning, and interval speed training. Along with ATAC, battalions have also incorporated components of fitness programs such as the Ranger Athlete Warrior program and CrossFit (Crossfit, Inc, Santa Monica, CA) an extreme conditioning program (ECP). To determine if these new programs (ATAC, ECP) had an effect on injury rates and physical fitness. Surveys were administered to collect personal characteristics, tobacco use, personal physical fitness training, Army physical fitness test results, and self-reported injuries. Medical record injury data were obtained 6 months before and 6 months after the implementation of the new program. Predictors of injury risk were assessed using multivariate logistic regression. Odds ratios (OR) and 95% confidence intervals (CI) were reported. Injury incidence among Soldiers increased 12% for overall injuries and 16% for overuse injuries after the implementation of the ATAC/ECPs. However, injury incidence among Soldiers not participating in ATAC/ECPs also increased 14% for overall injuries and 10% for overuse injuries. Risk factors associated with higher injury risk for Soldiers participating in ATAC/ECPs included: greater mileage run per week during unit physical training (OR (>16 miles per week÷≤7 miles per week)=2.24, 95% CI, 1.33-3.80); higher body mass index (BMI) (OR (BMI 25-29.9÷BMI<25)=1.77, 95% CI, 1.29-2.44), (OR (BMI =30÷BMI<25)=2.72, 95% CI, 1.67-4.43); cigarette use (OR (smoker÷nonsmoker)=1.80, 95% CI, 1.34-2.42); poor performance on the 2-mile run during

  3. EXTREME METEOROLOGICAL CONDITIONS AND METABOLIC PROFILE IN HIGH YIELDING HOLSTEINFRIESIAN DAIRY COWS

    Directory of Open Access Journals (Sweden)

    Z. GERGÁCZ

    2008-10-01

    Full Text Available The impact of two years (2002 and 2003 with different summer temperature extremes on variation in metabolic profile was analyzed in blood and urine samples taken from healthy, primiparous (n = 371 and multiparous (n = 795 high yielding Holstein-Friesian dairy cows. In this study main focus was lead on three most critical physiological phases, thus cows were assigned into three groups as follows: (1 dry cows for 10 days prior to calving; (2 cows 1-30 days after delivery, and (3 cows with more than 31 days post partum. Findings reveal clear response of the cows to heat in selected blood (hemoglobin, plasma aceto-acetic-acid, FFA, AST, glucose, urea and urine (pH, NABE and urea parameters. In the majority of cows, glucose and hemoglobin level, one of the most significant blood parameters, indicated symptoms of insufficient energy supply. Further metabolic indicators differed more or less from reference values depending on actual condition. Due to heat load dry matter intake has been decreased even by 10-15 per cent in primiparous cows. They were expected to increase body weight and size and simultaneously produce attain at large milk yields. In doing so that cows would have require large amount of nutrients. Out of parameters such as hemoglobin, glucose, FFA, AST and blood-urea differed from the reference values in most cases; however, this phenomenon seemed to be present in almost every case for hemoglobin and glucose. The lack of energy caused by heat stress can be contributed to the decrease of dry matter intake which has been indicated by the urea levels and pH both in blood and urine prevailing unfavorable and insufficient feeding practice. The results reconfirm the need to reconsider both the actual feeding practice (e.g. to increase of nutrient content in rations, reduce the intake of soluble proteins in rumen, pay attention of crude fiber in Total Mixed Rations (TMR, NDF and ADF, avoid overfeeding of inorganic buffers, to control moisture

  4. Crystallization and Thermoelectric Transport in Semiconductor Micro- and Nanostructures Under Extreme Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Gokirmak, Ali [Univ. of Connecticut, Storrs, CT (United States); Silva, Helena [Univ. of Connecticut, Storrs, CT (United States)

    2017-08-30

    This project focused on thermoelectric transport in semiconductor micro and nanostructures where moderate and typical operating voltages and currents lead to extreme thermal gradients and current densities. Models that describe behavior of semiconducting materials typically assume an equilibrium condition or slight deviations from it. In these cases the generation-recombination processes are assumed to have reached a local equilibrium for a given temperature. Hence, free carrier concentrations and their mobilities, band-gap, thermal conductivity, thermoelectric properties, mobility of atoms and mechanical properties of the material, can be described as a function of temperature. In the case of PN junctions under electrical bias, carrier concentrations can change up to ~ 1020 cm-3 and a drift-diffusion approximation is typically used to obtain the carrier concentrations while assuming that the material properties do not change. In non-equilibrium conditions, the assumption that the material properties remain the same may not be valid. While the increased conduction-band electron concentration may not have a drastic effect on the material, large hole concentration is expected to soften the material as ‘a hole’ comes into existence as a broken bond in the lattice. As the hole density approaches 1022 cm-3, the number of bonds holding the lattice together is significantly reduced, making it easier to break additional bonds, reduce band-gap and inhibit phonon transport. As these holes move away from where they were generated, local properties are expected to deviate significantly from the equilibrium case. Hence, temperature alone is not sufficient to describe the behavior of the material. The behavior of the solid material close to a molten region (liquid-solid interfaces) is also expected to deviate from the equilibrium case as a function of hole injection rate, which can be drastically increased or decreased in the presence of an electric field. In the past years

  5. Investigating the Effects of Simulated Space conditions on Novel Extremely Halophilic Archaea: Halovarius Luteus gen. nov., sp. nov.

    Science.gov (United States)

    Feshangsaz, Niloofar; Van Loon, ing.. Jack J. W. A.; Nazmi, Kamran; Semsarha, Farid

    2016-07-01

    Studying halophiles from different environments of Earth provide new insights into our search for life in the universe. Haloarchaea show some unique characteristics and physiological adaptations like acidic proteins against harsh environments such as natural brine with salt concentration approaching saturation (5 M) and regions with low active water. These properties make haloarchaea interesting candidate for astrobiological studies. Halovarius luteus gen. nov., sp. nov. a novel extremely halophilic archaeon from Urmia salt lake, in Iran has been chosen to explore its resistance against a series of extreme conditions. The aim of this study is to assess the resistance of strain DA50T under the effects of simulated space conditions like simulated microgravity, hypergravity, and desiccation. In this paper we will discuss the results of these studies where we specifically focus on changes in carotenoid pigments production and whole cell proteome. This is the first report of very novel Iranian archaea in response to extreme space conditions. The pigments were extracted by acetone and methanol. Pigments were analyzed by scanning the absorbance spectrum in the UV-VIS spectrophotometer. And they were separated by TLC. Whole protein from cell lysate supernatant was extracted after lysis with Bacterial Protein Extraction Reagent and fractionated by RP-HPLC using C18 column. Proteome analyzed by electrophoresis (SDS-PAGE), and MALDI-TOF. Carotenoid pigments are formed under different extreme conditions such as dry environment and gravitational changes. Also the protein composition exhibits alterations after exposure to the same conditions. Our conclusion is that pigments and proteins formation depend on the growth circumstances. Halophiles use this as an adaptation to survive under different environmental conditions.

  6. Multi-core MgO NPs(at)C core-shell nanospheres for selective CO2 capture under mild conditions

    International Nuclear Information System (INIS)

    Tae Kyung Kim; Kyung Joo Lee; Hoi Ri Moon; Junhan Yuh; Sang Kyu Kwak

    2014-01-01

    The core-shell structures have attracted attention in catalysis, because the outer shells isolate the catalytically active NP cores and prevent the possibility of sintering of core particles during catalytic reaction under physically and chemically harsh conditions. We aimed to adopt this core-shell system for CO 2 sorption materials. In this study, a composite material of multi-core 3 nm-sized magnesium oxide nanoparticles embedded in porous carbon nanospheres (MgO NPs(at)C) was synthesized by a gas phase reaction via a solvent-free process. It showed selective CO 2 adsorption capacity over N 2 under mild regeneration conditions. (authors)

  7. Extreme summer temperatures in Iberia: health impacts and associated synoptic conditions

    OpenAIRE

    Garcia-Herrera , R.; Diaz , J.; Trigo , R. M.; Hernández , E.

    2005-01-01

    This paper examines the effect of extreme summer temperatures on daily mortality in two large cities of Iberia: Lisbon (Portugal) and Madrid (Spain). Daily mortality and meteorological variables are analysed using the same methodology based on Box-Jenkins models. Results reveal that in both cases there is a triggering effect on mortality when maximum daily temperature exceeds a given threshold (34°C in Lisbon and 36°C in Madrid). The impact of most intense heat events is very ...

  8. Sediment Dynamics Within Buffer Zone and Sinkhole Splay Areas Under Extreme Soil Disturbance Conditions.

    Science.gov (United States)

    Schoonover, Jon E; Crim, Jackie F; Williard, Karl W J; Groninger, John W; Zaczek, James J; Pattumma, Klairoong

    2015-09-01

    Sedimentation dynamics were assessed in sinkholes within training areas at Ft. Knox Military Installation, a karst landscape subjected to decades of tracked vehicle use and extreme soil disturbance. Sinkholes sampled were sediment-laden and behaved as intermittent ponds. Dendrogeomorphic analyses were conducted using willow trees (Salix spp.) located around the edge of 18 sinkholes to estimate historical sedimentation rates, and buried bottles were installed in 20 sinkholes at the center, outer edge, and at the midpoint between the center and edge to estimate annual sedimentation rates. Sedimentation data were coupled with vegetation characteristics of sinkhole buffers to determine relationships among these variables. The dendrogeomorphic method estimated an average accumulation rate of 1.27 cm year(-1) translating to a sediment loss rate of 46.1 metric ton year(-1) from the training areas. However, sediment export to sinkholes was estimated to be much greater (118.6 metric ton year(-1)) via the bottle method. These data suggest that the latter method provided a more accurate estimate since accumulation was greater in the center of sinkholes compared to the periphery where dendrogeomorphic data were collected. Vegetation data were not tightly correlated with sedimentation rates, suggesting that further research is needed to identify a viable proxy for direct measures of sediment accumulation in this extreme deposition environment. Mitigation activities for the sinkholes at Ft. Knox's tank training area, and other heavily disturbed karst environments where extreme sedimentation exists, should consider focusing on flow path and splay area management.

  9. Correlations in condensed matter under extreme conditions a tribute to Renato Pucci on the occasion of his 70th birthday

    CERN Document Server

    2017-01-01

    This book addresses a wide range of topics relating to the properties and behavior of condensed matter under extreme conditions such as intense magnetic and electric fields, high pressures, heat and cold, and mechanical stresses. It is divided into four sections devoted to condensed matter theory, molecular chemistry, theoretical physics, and the philosophy and history of science. The main themes include electronic correlations in material systems under extreme pressure and temperature conditions, surface physics, the transport properties of low-dimensional electronic systems, applications of the density functional theory in molecular systems, and graphene. The book is the outcome of a workshop held at the University of Catania, Italy, in honor of Professor Renato Pucci on the occasion of his 70th birthday. It includes selected invited contributions from collaborators and co-authors of Professor Pucci during his long and successful career, as well as from other distinguished guest authors.

  10. Effect of load and reciprocating velocity on the transition from mild to severe wear behavior of Al-Si-SiCp composites in reciprocating conditions

    International Nuclear Information System (INIS)

    Rajeev, V.R.; Dwivedi, D.K.; Jain, S.C.

    2010-01-01

    In the present paper, the effect of normal load and reciprocating velocity on transition from mild to severe wear of A319/15%SiC p , A336/15%SiC p , and A390/15%SiC p composites have been reported. Composites were produced through liquid metal metallurgy route. Adhesive wear behavior of composites was studied under dry reciprocating conditions using indigenously developed reciprocating friction wear test rig conforming to ASTM Standard G133-05. It was found that increase in normal load increases wear rate and depending upon the reciprocating velocity and type of composites, mode of wear changes from mild oxidative to severe metallic wear was noticed. The load corresponding to the transition from mild to severe wear usually termed as transition load was found to decrease with increase in reciprocating velocity and reduction in silicon content in the alloys used for the development of Al-Si-SiC p composites. At 1 m/s reciprocating velocity, the transition load for A319/15%SiC p , A336/15%SiC p and A390/15%SiC p composites were found to be in the range of 60-90 N, 60-105 N and 60-120 N respectively. Scanning electron microscope (SEM) study of wear surface and wear debris were conducted to analyze the mode of wear and operating wear mechanism. Severe wear was characterized by massive plastic deformation and gross material removal while the mild wear was found to be associated with delamination and scoring as main wear mechanisms responsible for material loss. Wear mechanism maps for different Al-(6-18)%Si-15%SiC p composites were proposed in reciprocating contacts.

  11. Pd/Nb2O5/SiO2 catalyst for the direct hydrodeoxygenation of biomass-related compounds to liquid alkanes under mild conditions.

    Science.gov (United States)

    Shao, Yi; Xia, Qineng; Liu, Xiaohui; Lu, Guanzhong; Wang, Yanqin

    2015-05-22

    A simple Pd-loaded Nb2 O5 /SiO2 catalyst was prepared for the hydrodeoxygenation of biomass-related compounds to alkanes under mild conditions. Niobium oxide dispersed in silica (Nb2 O5 /SiO2 ) as the support was prepared by the sol-gel method and characterized by various techniques, including N2 adsorption, XRD, NH3 temperature-programmed desorption (TPD), TEM, and energy-dispersive X-ray spectroscopy (EDAX) atomic mapping. The characterization results showed that the niobium oxide species were amorphous and well dispersed in silica. Compared to commercial Nb2 O5 , Nb2 O5 /SiO2 has significantly more active niobium oxide species exposed on the surface. Under mild conditions (170 °C, 2.5 MPa), Pd/10 %Nb2 O5 /SiO2 was effective for the hydrodeoxygenation reactions of 4-(2-furyl)-3-buten-2-one (aldol adduct of furfural with acetone), palmitic acid, tristearin, and diphenyl ether (model compounds of microalgae oils, vegetable oils, and lignin), which gave high yields (>94 %) of alkanes with little CC bond cleavage. More importantly, owing to the significant promotion effect of NbOx species on CO bond cleavage and the mild reaction conditions, the CC cleavage was considerably restrained, and the catalyst showed an excellent activity and stability for the hydrodeoxygenation of palmitic acid with almost no decrease in hexadecane yield (94-95 %) in a 150 h time-on-stream test. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  12. Autophagy sustains the survival of human pancreatic cancer PANC-1 cells under extreme nutrient deprivation conditions.

    Science.gov (United States)

    Kim, Sang Eun; Park, Hye-Jin; Jeong, Hye Kyoung; Kim, Mi-Jung; Kim, Minyeong; Bae, Ok-Nam; Baek, Seung-Hoon

    2015-07-31

    Pancreatic ductal adenocarcinomas are an extremely aggressive and devastating type of cancer with high mortality. Given the dense stroma and poor vascularization, accessibility to nutrients is limited in the tumor microenvironment. Here, we aimed to elucidate the role of autophagy in promoting the survival of human pancreatic cancer PANC-1 cells exposed to nutrient-deprived media (NDM) lacking glucose, amino acids, and serum. NDM inhibited Akt activity and phosphorylation of p70 S6K, and induced AMPK activation and mitochondrial depolarization. NDM also time-dependently increased LC3-II accumulation, number of GFP-LC3 puncta, and colocalization between GFP-LC3 and lysosomes. These results suggested that autophagy was progressively activated through Akt- and AMPK-mTOR pathway in nutrient-deficient PANC-1 cells. Autophagy inhibitors (chloroquine and wortmannin) or silencing of Atg5 augmented PANC-1 cell death in NDM. In cells exposed to NDM, chloroquine and wortmannin induced apoptosis and Z-VAD-fmk inhibited cytotoxicity of these inhibitors. These data demonstrate that autophagy is anti-apoptotic and sustains the survival of PANC-1 cells following extreme nutrient deprivation. Autophagy modulation may be a viable therapeutic option for cancer cells located in the core of solid tumors with a nutrient-deficient microenvironment. Copyright © 2015 Elsevier Inc. All rights reserved.

  13. Review Article: Atmospheric conditions inducing extreme precipitation over the eastern and western Mediterranean

    Science.gov (United States)

    Dayan, U.; Nissen, K.; Ulbrich, U.

    2015-11-01

    This review discusses published studies of heavy rainfall events over the Mediterranean Basin, combining them in a more general picture of the dynamic and thermodynamic factors and processes that produce heavy rain storms. It distinguishes the western and eastern Mediterranean in order to point out specific regional peculiarities. The crucial moisture for developing intensive convection over these regions can be originated not only from the adjacent Mediterranean Sea but also from distant upwind sources. Transport from remote sources is usually in the mid-tropospheric layers and associated with specific features and patterns of the larger-scale circulations. The synoptic systems (tropical and extratropical) that account for most of the major extreme precipitation events and the coupling of circulation and extreme rainfall patterns are presented. Heavy rainfall over the Mediterranean Basin is caused at times in concert by several atmospheric processes working at different atmospheric scales, such as local convection, upper synoptic-scale-level troughs, and mesoscale convective systems. Under tropical air-mass intrusions, convection generated by static instability seems to play a more important role than synoptic-scale vertical motions. Locally, the occurrence of torrential rains and their intensity is dependent on factors such as temperature profiles and implied instability, atmospheric moisture, and lower-level convergence.

  14. EXTREME CONDITIONS IN A CLOSE ANALOG TO THE YOUNG SOLAR SYSTEM: HERSCHEL OBSERVATIONS OF ε ERIDANI

    Energy Technology Data Exchange (ETDEWEB)

    Greaves, J. S. [SUPA, Physics and Astronomy, University of St Andrews, North Haugh, St Andrews, Fife KY16 9SS (United Kingdom); Sibthorpe, B.; Holland, W. S. [UK Astronomy Technology Centre, Royal Observatory Edinburgh, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); Acke, B.; Vandenbussche, B.; Blommaert, J. A. D. L. [Instituut voor Sterrenkunde, K. U. Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Pantin, E. E. [Laboratoire AIM, CEA/DSM-CNRS-Universit Paris Diderot, IRFU/Service dAstrophysique, Bat.709, CEA-Saclay, F-91191 Gif- sur-Yvette Cedex (France); Olofsson, G.; Brandeker, A.; De Vries, B. L. [Stockholm University Astrobiology Centre, SE-106 91 Stockholm (Sweden); Dominik, C. [Astronomical Institute Anton Pannekoek, University of Amsterdam, P.O. Box 94249, 1090-GE Amsterdam (Netherlands); Barlow, M. J. [Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom); Bendo, G. J. [Jodrell Bank Centre for Astrophysics, School of Physics and Astronomy, University of Manchester, Oxford Road, Manchester M13 9PL (United Kingdom); Dent, W. R. F. [ALMA SCO, Alonso de Cordova 3107, Vitacura, Casilla 763 0355, Santiago (Chile); Di Francesco, J. [Herzberg Astronomy and Astrophysics Programs, National Research Council of Canada, 5071 West Saanich Road, Victoria, BC, V9E 2E7 (Canada); Fridlund, M. [ESA, SRE-SA, Keplerlaan 1, NL-2201 AZ Noordwijk (Netherlands); Gear, W. K. [School of Physics and Astronomy, Cardiff University, Queens Buildings, The Parade, Cardiff CF24 3AA (United Kingdom); Harvey, P. M. [Astronomy Department, University of Texas, Austin, TX 78712 (United States); Hogerheijde, M. R. [Leiden Observatory, Leiden University, P.O. Box 9513, 2300-RA Leiden (Netherlands); Ivison, R. J., E-mail: jsg5@st-andrews.ac.uk [Institute for Astronomy, University of Edinburgh, Royal Observatory, Blackford Hill, Edinburgh EH9 3HJ (United Kingdom); and others

    2014-08-10

    Far-infrared Herschel images of the ε Eridani system, seen at a fifth of the Sun's present age, resolve two belts of debris emission. Fits to the 160 μm PACS image yield radial spans for these belts of 12-16 and 54-68 AU. The south end of the outer belt is ≈10% brighter than the north end in the PACS+SPIRE images at 160, 250, and 350 μm, indicating a pericenter glow attributable to a planet ''c''. From this asymmetry and an upper bound on the offset of the belt center, this second planet should be mildly eccentric (e{sub c} ≈ 0.03-0.3). Compared to the asteroid and Kuiper Belts of the young Sun, the ε Eri belts are intermediate in brightness and more similar to each other, with up to 20 km sized collisional fragments in the inner belt totaling ≈5% of an Earth mass. This reservoir may feed the hot dust close to the star and could send many impactors through the Habitable Zone, especially if it is being perturbed by the suspected planet ε Eri b, at semi-major axis ≈3 AU.

  15. Impact of urban WWTP and CSO fluxes on river peak flow extremes under current and future climate conditions.

    Science.gov (United States)

    Keupers, Ingrid; Willems, Patrick

    2013-01-01

    The impact of urban water fluxes on the river system outflow of the Grote Nete catchment (Belgium) was studied. First the impact of the Waste Water Treatment Plant (WWTP) and the Combined Sewer Overflow (CSO) outflows on the river system for the current climatic conditions was determined by simulating the urban fluxes as point sources in a detailed, hydrodynamic river model. Comparison was made of the simulation results on peak flow extremes with and without the urban point sources. In a second step, the impact of climate change scenarios on the urban fluxes and the consequent impacts on the river flow extremes were studied. It is shown that the change in the 10-year return period hourly peak flow discharge due to climate change (-14% to +45%) was in the same order of magnitude as the change due to the urban fluxes (+5%) in current climate conditions. Different climate change scenarios do not change the impact of the urban fluxes much except for the climate scenario that involves a strong increase in rainfall extremes in summer. This scenario leads to a strong increase of the impact of the urban fluxes on the river system.

  16. Influence of extreme low temperature conditions on the dynamic mechanical properties of carbon fiber reinforced polymers

    Science.gov (United States)

    Zaoutsos, S. P.; Zilidou, M. C.

    2017-12-01

    In the current study dynamic mechanical analysis (DMA) is performed in CFRPs that have been exposed for certain periods of time to extreme low temperatures. Through experimental data arising from respective DMA tests the influence of low temperature exposure (-40 °C) on the dynamic mechanical properties is studied. DMA tests were conducted in CFRP specimens in three point bending mode at both frequency and thermal scans in order to determine the viscoelastic response of the material in low temperatures. All experimental tests were run both for aged and pristine materials for comparison purposes. The results occurred reveal that there is deterioration both on transition temperature (Tg) and storage modulus values while there is also a moderate increase in the damping ability of the tested material as expressed by the factor tanδ as the period of exposure to low temperature increases.

  17. Experimental and theoretical study of electronic structure of aluminum in extreme conditions with X-ray absorption spectroscopy

    International Nuclear Information System (INIS)

    Festa, Floriane

    2013-01-01

    Matter in extreme conditions belongs to Warm Dense Matter regime which lays between dense plasma regime and condensed matter. This regime is still not well known, indeed it is very complex to generate such plasma in the laboratory to get experimental data and validate models. The goal of this thesis is to study electronic structure of aluminum in extreme conditions with X-ray absorption spectroscopy. Experimentally aluminum has reached high densities and high temperatures, up to now unexplored. An X-ray source has also been generated to probe highly compressed aluminum. Two spectrometers have recorded aluminum absorption spectra and aluminum density and temperature conditions have been deduced thanks to optical diagnostics. Experimental spectra have been compared to ab initio spectra, calculated in the same conditions. The theoretical goal was to validate the calculation method in high densities and high temperatures regime with the study of K-edge absorption modifications. We also used absorption spectra to study the metal-non metal transition which takes place at low density (density ≤ solid density). This transition could be study with electronic structure modifications of the system. (author) [fr

  18. Fabrication of Electrochemically Reduced Graphene Oxide Modified Gas Diffusion Electrode for In-situ Electrochemical Advanced Oxidation Process under Mild Conditions

    International Nuclear Information System (INIS)

    Dong, Heng; Su, Huimin; Chen, Ze; Yu, Han; Yu, Hongbing

    2016-01-01

    With aim to develop an efficient heterogeneous metal-free cathodic electrochemical advance oxidation process (CEAOP) for persistent organic pollutants (POPs) removal from wastewater under mild conditions, electrochemically reduced graphene oxide (ERGO)-modified gas diffusion electrode (GDE) was prepared for oxygen-containing radicals production via electrochemical oxygen reduction reaction (ORR). A detailed physical characterization was carried out by SEM, Raman spectroscopy, XRD and XPS. The electrocatalytic behavior for ORR was investigated by electrochemical measurements and electrolysis experiments under constant current density. Bisphenol A (BPA) of 20 mg L −1 was used as a model of POPs to evaluate the performance of the CEAOP with ERGO-modified GDE. The results showed that the defects concentration and electrochemical active sites of the ERGO was increased as the reduction time (30 min, 60 min and 120 min), leading to different catalysis on ORR. ·O 2 generation via one-electron ORR was found under the electrocatalysis of ERGO (60 min and 120 min), contributing to a complete degradation of BPA within 20 min and a mineralization current efficiency (MCE) of 74.60%. An alternative metal-free CEAOP independent of Fenton reaction was established based on ERGO-modified GDE for POPs removal from wastewater under mild conditions.

  19. Halophilic archaea on Earth and in space: growth and survival under extreme conditions.

    Science.gov (United States)

    Oren, Aharon

    2014-12-13

    Salts are abundant on Mars, and any liquid water that is present or may have been present on the planet is expected to be hypersaline. Halophilic archaea (family Halobacteriaceae) are the microorganisms best adapted to life at extremes of salinity on Earth. This paper reviews the properties of the Halobacteriaceae that may make the group good candidates for life also on Mars. Many species resist high UV and gamma radiation levels; one species has survived exposure to vacuum and radiation during a space flight; and there is at least one psychrotolerant species. Halophilic archaea may survive for millions of years within brine inclusions in salt crystals. Many species have different modes of anaerobic metabolism, and some can use light as an energy source using the light-driven proton pump bacteriorhodopsin. They are also highly tolerant to perchlorate, recently shown to be present in Martian soils, and some species can even use perchlorate as an electron acceptor to support anaerobic growth. The presence of characteristic carotenoid pigments (α-bacterioruberin and derivatives) makes the Halobacteriaceae easy to identify by Raman spectroscopy. Thus, if present on Mars, such organisms may be detected by Raman instrumentation planned to explore Mars during the upcoming ExoMars mission. © 2014 The Author(s) Published by the Royal Society. All rights reserved.

  20. Fiber Bragg Grating Dilatometry in Extreme Magnetic Field and Cryogenic Conditions

    Directory of Open Access Journals (Sweden)

    Marcelo Jaime

    2017-11-01

    Full Text Available In this work, we review single mode SiO2 fiber Bragg grating techniques for dilatometry studies of small single-crystalline samples in the extreme environments of very high, continuous, and pulsed magnetic fields of up to 150 T and at cryogenic temperatures down to <1 K. Distinct millimeter-long materials are measured as part of the technique development, including metallic, insulating, and radioactive compounds. Experimental strategies are discussed for the observation and analysis of the related thermal expansion and magnetostriction of materials, which can achieve a strain sensitivity (ΔL/L as low as a few parts in one hundred million (≈10−8. The impact of experimental artifacts, such as those originating in the temperature dependence of the fiber’s index of diffraction, light polarization rotation in magnetic fields, and reduced strain transfer from millimeter-long specimens, is analyzed quantitatively using analytic models available in the literature. We compare the experimental results with model predictions in the small-sample limit, and discuss the uncovered discrepancies.

  1. Lower Extremity Salvage with Thoracodorsal Artery Perforator Free Flap in Condition of Symmetrical Peripheral Gangrene

    Directory of Open Access Journals (Sweden)

    Soo Yeon Lim

    2018-01-01

    Full Text Available Symmetrical peripheral gangrene (SPG is rare but devastating complication which is characterized by symmetrical ischemic change of the distal extremities. In this report, we describe our management protocol for SPG, focusing on surgical approaches. Between January 2007 and February 2016, 10 thoracodorsal artery perforator (TDAP free flaps were performed in 6 patients with SPG. Three patients were male and mean age was 56 (range, 44–69 years. All the patients were in shock. The causes of shock were sepsis in 4 cases, respiratory arrest in 1 case, and hypovolemia in 1 case. Eight transmetatarsal amputations and 2 Lisfranc amputations were performed. Flap sizes ranged from 7 × 11 cm to 25 × 15 cm. There were 3 cases of partial necrosis of the flap: two healed conservatively with dressings and one required skin graft. Three of the patients were later able to walk independently at Functional Ambulation Classification (FAC level 6, one patient could walk independently on level surfaces at FAC level 5, and 2 could walk independently using walking aids, classified at FAC level 4. The average follow-up period was 18 (range, 6–54 months. In patients with SPG, minimal bone amputation and foot salvage with TDAP flaps were successful. Separate reconstruction of bone and soft tissue had good outcomes.

  2. A conditional extreme value theory approach in value-at-risk forecasting: Evidence from Southeastern Europe and USA market

    Directory of Open Access Journals (Sweden)

    Totić Selena

    2015-01-01

    Full Text Available As a consequence of the recent financial crisis, the adequacy of different Value-at-Risk (VaR methodologies was heavily questioned. Current practice in VaR assessment relies on modeling the whole distribution of returns. As an alternative, in this paper we model tail behavior of returns, and thus VaR, using conditional Extreme Value Theory (EVT, which combines EVT and GARCH methodology. Moreover, we examine the performance of conditional EVT with the daily returns of seven stock market indices, of which six are from Southeastern Europe (BelexLine, BET, BUX, CROBEX, SBITOP, SOFIX from the period of September 2004 - April 2013, and one from USA market (Standard&Poors 500 Index from the period January 1998 - April 2013. Backtesting of historical daily returns proves that conditional EVT model gives good predictions for all indices and for all confidence levels.

  3. Highly Chemoselective Reduction of Amides (Primary, Secondary, Tertiary) to Alcohols using SmI2/Amine/H2O under Mild Conditions

    Science.gov (United States)

    2014-01-01

    Highly chemoselective direct reduction of primary, secondary, and tertiary amides to alcohols using SmI2/amine/H2O is reported. The reaction proceeds with C–N bond cleavage in the carbinolamine intermediate, shows excellent functional group tolerance, and delivers the alcohol products in very high yields. The expected C–O cleavage products are not formed under the reaction conditions. The observed reactivity is opposite to the electrophilicity of polar carbonyl groups resulting from the nX → π*C=O (X = O, N) conjugation. Mechanistic studies suggest that coordination of Sm to the carbonyl and then to Lewis basic nitrogen in the tetrahedral intermediate facilitate electron transfer and control the selectivity of the C–N/C–O cleavage. Notably, the method provides direct access to acyl-type radicals from unactivated amides under mild electron transfer conditions. PMID:24460078

  4. Observations and Predictions of Wave Runup, Extreme Water Levels, and Medium-Term Dune Erosion during Storm Conditions

    Directory of Open Access Journals (Sweden)

    Serge Suanez

    2015-07-01

    Full Text Available Monitoring of dune erosion and accretion on the high-energy macrotidal Vougot beach in North Brittany (France over the past decade (2004–2014 has revealed significant morphological changes. Dune toe erosion/accretion records have been compared with extreme water level measurements, defined as the sum of (i astronomic tide; (ii storm surge; and (iii vertical wave runup. Runup parameterization was conducted using swash limits, beach profiles, and hydrodynamic (Hm0, Tm0,–1, and high tide water level—HTWL data sets obtained from high frequency field surveys. The aim was to quantify in-situ environmental conditions and dimensional swash parameters for the best calibration of Battjes [1] runup formula. In addition, an empirical equation based on observed tidal water level and offshore wave height was produced to estimate extreme water levels over the whole period of dune morphological change monitoring. A good correlation between this empirical equation (1.01Hmoξo and field runup measurements (Rmax was obtained (R2 85%. The goodness of fit given by the RMSE was about 0.29 m. A good relationship was noticed between dune erosion and high water levels when the water levels exceeded the dune foot elevation. In contrast, when extreme water levels were below the height of the toe of the dune sediment budget increased, inducing foredune recovery. These erosion and accretion phases may be related to the North Atlantic Oscillation Index.

  5. Extreme fire events are related to previous-year surface moisture conditions in permafrost-underlain larch forests of Siberia

    International Nuclear Information System (INIS)

    Forkel, Matthias; Beer, Christian; Thonicke, Kirsten; Cramer, Wolfgang; Bartalev, Sergey; Schmullius, Christiane

    2012-01-01

    Wildfires are a natural and important element in the functioning of boreal forests. However, in some years, fires with extreme spread and severity occur. Such severe fires can degrade the forest, affect human values, emit huge amounts of carbon and aerosols and alter the land surface albedo. Usually, wind, slope and dry air conditions have been recognized as factors determining fire spread. Here we identify surface moisture as an additional important driving factor for the evolution of extreme fire events in the Baikal region. An area of 127 000 km 2 burned in this region in 2003, a large part of it in regions underlain by permafrost. Analyses of satellite data for 2002–2009 indicate that previous-summer surface moisture is a better predictor for burned area than precipitation anomalies or fire weather indices for larch forests with continuous permafrost. Our analysis advances the understanding of complex interactions between the atmosphere, vegetation and soil, and how coupled mechanisms can lead to extreme events. These findings emphasize the importance of a mechanistic coupling of soil thermodynamics, hydrology, vegetation functioning, and fire activity in Earth system models for projecting climate change impacts over the next century. (letter)

  6. Structural studies of disordered materials using high-energy x-ray diffraction from ambient to extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Kohara, Shinji [Japan Synchrotron Radiation Research Institute (SPring-8/JASRI), 1-1-1 Kouto, Sayo, Hyogo 679-5198 (Japan); Itou, Masayoshi [Japan Synchrotron Radiation Research Institute (SPring-8/JASRI), 1-1-1 Kouto, Sayo, Hyogo 679-5198 (Japan); Suzuya, Kentaro [Japan Atomic Energy Agency (J-PARC/JAEA), Tokai, Naka, Ibaraki 319-1195 (Japan); Inamura, Yasuhiro [Japan Atomic Energy Agency (J-PARC/JAEA), Tokai, Naka, Ibaraki 319-1195 (Japan); Sakurai, Yoshiharu [Japan Synchrotron Radiation Research Institute (SPring-8/JASRI), 1-1-1 Kouto, Sayo, Hyogo 679-5198 (Japan); Ohishi, Yasuo [Japan Synchrotron Radiation Research Institute (SPring-8/JASRI), 1-1-1 Kouto, Sayo, Hyogo 679-5198 (Japan); Takata, Masaki [Japan Synchrotron Radiation Research Institute (SPring-8/JASRI), 1-1-1 Kouto, Sayo, Hyogo 679-5198 (Japan)

    2007-12-19

    High-energy x-rays from a synchrotron radiation source allow us to obtain high-quality diffraction data for disordered materials from ambient to extreme conditions, which is necessary for revealing the detailed structures of glass, liquid and amorphous materials. We introduced high-energy x-ray diffraction beamlines and a dedicated diffractometer for glass, liquid and amorphous materials at SPring-8 and report the recent developments of ancillary equipment. Furthermore, the structures of liquid and amorphous materials determined from the high-energy x-ray diffraction data obtained at SPring-8 are discussed.

  7. Studies of nuclei under the extreme conditions of density, temperature, isospin asymmetry and the phase diagram of hadronic matter

    Energy Technology Data Exchange (ETDEWEB)

    Mekjian, Aram [Rutgers Univ., Piscataway, NJ (United States). Dept. of Physics and Astronomy

    2016-10-18

    The main emphasis of the entire project is on issues having to do with medium energy and ultra-relativistic energy and heavy ion collisions. A major goal of both theory and experiment is to study properties of hot dense nuclear matter under various extreme conditions and to map out the phase diagram in density or chemical potential and temperature. My studies in medium energy nuclear collisions focused on the liquid-gas phase transition and cluster yields from such transitions. Here I developed both the statistical model of nuclear multi-fragmentation and also a mean field theory.

  8. Legal and Psychological Fundamentals of Extreme Communication in the Conditions of Hostages Detention (Bibliography Review

    Directory of Open Access Journals (Sweden)

    Zverev V. O.

    2014-01-01

    Full Text Available An attempt is made to generalize and analyze some accumulated scientific knowledge in the sphere of psychological nuances arising in the process of negotiations with criminals in the conditions of hostages detention, the experience shared by Soviet and Russian scientists

  9. Extreme Changes in Stream Geomorphic Conditions induced by Fluvial Scour in Bridges

    Science.gov (United States)

    Özcan, O.; Ozcan, O.

    2016-12-01

    The numerous complexities associated with bridge scour have caused scour to be one of the most active topics of stream geomorphic research. The assessment of local scouring mechanism around bridge piers provides information for decision-making regarding the pile footing design, predicting the safety of bridges under critical scoured conditions, and as a result, may help prevent unnecessary loses. In the study, bridge design plans and HEC-RAS modeling were used for the assessment of changes in stream geomorphic conditions. The derived fluvial scour depths were compared with the field measurements and the empirical formula which is based on stream flow discharge rate, streambed condition and shape of river. Preliminary results revealed that bridge damage resulting from the flood event in 2003 induced substantial scour around bridge piles. Afterwards, significant stream bed change was observed under the influence of fluvial scour in another flood occurred in 2009. Consequently, geomorphic conditions of the stream bed should be considered in the structural design of the bridges.

  10. Extreme quantile estimation for dependent data with applications to finance

    OpenAIRE

    Drees, Holger

    2002-01-01

    The asymptotic normality of a class of estimators for extreme quantiles is established under mild structural conditions on the observed stationary \\beta-mixing time series. Consistent estimators of the asymptotic variance are introduced, which render possible the construction of asymptotic confidence intervals for the extreme quantiles. Moreover, it is shown that many well-known time series models satisfy our conditions. Then the theory is applied to a time series of returns of a stock in...

  11. Extreme temperatures increase the deleterious consequences of inbreeding under laboratory and semi-natural conditions

    DEFF Research Database (Denmark)

    Kristensen, Torsten Nygård; Barker, J. Stuart F.; Pedersen, Kamilla Sofie

    2008-01-01

    when compared with non-inbred lines of Drosophila melanogaster under different temperature conditions. Egg-to-adult viability, developmental time and sex ratio of emerging adults are studied under low, intermediate and high temperatures under laboratory as well as semi-natural conditions. The results...... show inbreeding depression for egg-to-adult viability. The level of inbreeding depression is highly dependent on test temperature and is observed only at low and high temperatures. Inbreeding did not affect the developmental time or the sex ratio of emerging adults. However, temperature affected...... the sex ratio with more females relative to males emerging at low temperatures, suggesting that selection against males in pre-adult life stages is stronger at low temperatures. The coefficient of variation (CV) of egg-to-adult viability within and among lines is higher for inbred flies and generally...

  12. Novel portable press for synchrotron time-resolved 3-D micro-imagining under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Philippe, J.; Le Godec, Y., E-mail: yann.legodec@impmc.upmc.fr; Bergame, F.; Morand, M. [IMPMC, Université Pierre et Marie Curie, Paris (France); Mezouar, M.; Bauchau, S.; Alvarez-Murga, M. [European Synchrotron Radiation Facility, Grenoble (France); Perrillat, J. P. [Laboratoire de Géologie de Lyon, Université Claude Bernard Lyon1, Lyon (France); Bromiley, G.; Berg, M. [School of GeoSciences, University of Edinburgh, Edinburgh (United Kingdom); King, A.; Guignot, N.; Itié, J. P. [Synchrotron SOLEIL, St Aubin France (France); Atwood, Robert [Diamond Light Source Ltd., Harwell Science and Innovation Campus, Didcot (United Kingdom)

    2016-07-27

    Here we present the instrumental development to extend the synchrotron X-ray microtomography techniques to in situ studies under static compression (HP) or shear stress or the both conditions at high temperatures (HT). To achieve this, a new rotating tomography Paris-Edinburgh cell (rotoPEc) has been developed. This ultra-compact portable device, easily and successfully adapted to various multi-modal synchrotron experimental set-up at ESRF, SOLEIL and DIAMOND is explained in detail.

  13. Hyper-dry conditions provide new insights into the cause of extreme floods after wildfire

    Science.gov (United States)

    Moody, John A.; Ebel, Brian A.

    2012-01-01

    A catastrophic wildfire in the foothills of the Rocky Mountains near Boulder, Colorado provided a unique opportunity to investigate soil conditions immediately after a wildfire and before alteration by rainfall. Measurements of near-surface (θ; and matric suction, ψ), rainfall, and wind velocity were started 8 days after the wildfire began. These measurements established that hyper-dryconditions (θ 3 cm-3; ψ > ~ 3 x 105 cm) existed and provided an in-situ retention curve for these conditions. These conditions exacerbate the effects of water repellency (natural and fire-induced) and limit the effectiveness of capillarity and gravity driven infiltration into fire-affected soils. The important consequence is that given hyper-dryconditions, the critical rewetting process before the first rain is restricted to the diffusion–adsorption of water-vapor. This process typically has a time scale of days to weeks (especially when the hydrologic effects of the ash layer are included) that is longer than the typical time scale (minutes to hours) of some rainstorms, such that under hyper-dryconditions essentially no rain infiltrates. The existence of hyper-dryconditions provides insight into why, frequently during the first rain storm after a wildfire, nearly all rainfall becomes runoff causing extremefloods and debris flows.

  14. Extreme Hypoxic Conditions Induce Selective Molecular Responses and Metabolic Reset in Detached Apple Fruit

    Science.gov (United States)

    Cukrov, Dubravka; Zermiani, Monica; Brizzolara, Stefano; Cestaro, Alessandro; Licausi, Francesco; Luchinat, Claudio; Santucci, Claudio; Tenori, Leonardo; Van Veen, Hans; Zuccolo, Andrea; Ruperti, Benedetto; Tonutti, Pietro

    2016-01-01

    The ripening physiology of detached fruit is altered by low oxygen conditions with profound effects on quality parameters. To study hypoxia-related processes and regulatory mechanisms, apple (Malus domestica, cv Granny Smith) fruit, harvested at commercial ripening, were kept at 1°C under normoxic (control) and hypoxic (0.4 and 0.8 kPa oxygen) conditions for up to 60 days. NMR analyses of cortex tissue identified eight metabolites showing significantly different accumulations between samples, with ethanol and alanine displaying the most pronounced difference between hypoxic and normoxic treatments. A rapid up-regulation of alcohol dehydrogenase and pyruvate-related metabolism (lactate dehydrogenase, pyruvate decarboxylase, alanine aminotransferase) gene expression was detected under both hypoxic conditions with a more pronounced effect induced by the lowest (0.4 kPa) oxygen concentration. Both hypoxic conditions negatively affected ACC synthase and ACC oxidase transcript accumulation. Analysis of RNA-seq data of samples collected after 24 days of hypoxic treatment identified more than 1000 genes differentially expressed when comparing 0.4 vs. 0.8 kPa oxygen concentration samples. Genes involved in cell-wall, minor and major CHO, amino acid and secondary metabolisms, fermentation and glycolysis as well as genes involved in transport, defense responses, and oxidation-reduction appeared to be selectively affected by treatments. The lowest oxygen concentration induced a higher expression of transcription factors belonging to AUX/IAA, WRKY, HB, Zinc-finger families, while MADS box family genes were more expressed when apples were kept under 0.8 kPa oxygen. Out of the eight group VII ERF members present in apple genome, two genes showed a rapid up-regulation under hypoxia, and western blot analysis showed that apple MdRAP2.12 proteins were differentially accumulated in normoxic and hypoxic samples, with the highest level reached under 0.4 kPa oxygen. These data suggest

  15. Technology development of protein rich concentrates for nutrition in extreme conditions using soybean and meat by-products.

    Science.gov (United States)

    Kalenik, Tatiana K; Costa, Rui; Motkina, Elena V; Kosenko, Tamara A; Skripko, Olga V; Kadnikova, Irina A

    2017-01-01

    There is a need to develop new foods for participants of expeditions in extreme conditions, which must be self-sufficient. These foods should be light to carry, with a long shelf life, tasty and with  high nutrient density. Currently, protein sources are limited mainly to dried and canned meat. In this work, a protein-rich dried concentrate suitable for extreme expeditions was developed using soya, tomato, milk whey and meat by-products. Protein concentrates were developed using minced beef liver and heart, dehydrated and mixed with a soya protein-lycopene coagulate (SPLC) obtained from a solution prepared with germi- nated soybeans and mixed with tomato paste in milk whey, and finally dried. The technological parameters of pressing SPLC and of drying the protein concentrate were optimized using response surface methodology. The optimized technological parameters to prepare the protein concentrates were obtained, with 70:30 being the ideal ratio of minced meat to SPLC. The developed protein concentrates are characterized by a high calorific value of 376 kcal/100 g of dry product, with a water content of 98 g·kg-1, and 641-644 g·kg-1 of proteins. The essential amino acid indices are 100, with minimum essential amino acid content constitut- ing 100-128% of the FAO standard, depending on the raw meat used. These concentrates are also rich in micronutrients such as β-carotene and vitamin C. Analysis of the nutrient content showed that these non-perishable concentrates present a high nutritional value and complement other widely available vegetable concentrates to prepare a two-course meal. The soups and porridges prepared with these concentrates can be classified as functional foods, and comply with army requirements applicable to food products for extreme conditions.

  16. Mild oxidative stress induces redistribution of BACE1 in non-apoptotic conditions and promotes the amyloidogenic processing of Alzheimer's disease amyloid precursor protein.

    Directory of Open Access Journals (Sweden)

    Jiang-Li Tan

    Full Text Available BACE1 is responsible for β-secretase cleavage of the amyloid precursor protein (APP, which represents the first step in the production of amyloid β (Aβ peptides. Previous reports, by us and others, have indicated that the levels of BACE1 protein and activity are increased in the brain cortex of patients with Alzheimer's disease (AD. The association between oxidative stress (OS and AD has prompted investigations that support the potentiation of BACE1 expression and enzymatic activity by OS. Here, we have established conditions to analyse the effects of mild, non-lethal OS on BACE1 in primary neuronal cultures, independently from apoptotic mechanisms that were shown to impair BACE1 turnover. Six-hour treatment of mouse primary cortical cells with 10-40 µM hydrogen peroxide did not significantly compromise cell viability but it did produce mild oxidative stress (mOS, as shown by the increased levels of reactive radical species and activation of p38 stress kinase. The endogenous levels of BACE1 mRNA and protein were not significantly altered in these conditions, whereas a toxic H2O2 concentration (100 µM caused an increase in BACE1 protein levels. Notably, mOS conditions resulted in increased levels of the BACE1 C-terminal cleavage product of APP, β-CTF. Subcellular fractionation techniques showed that mOS caused a major rearrangement of BACE1 localization from light to denser fractions, resulting in an increased distribution of BACE1 in fractions containing APP and markers for trans-Golgi network and early endosomes. Collectively, these data demonstrate that mOS does not modify BACE1 expression but alters BACE1 subcellular compartmentalization to favour the amyloidogenic processing of APP, and thus offer new insight in the early molecular events of AD pathogenesis.

  17. Quantification of Cation Sorption to Engineered Barrier Materials Under Extreme Conditions

    Energy Technology Data Exchange (ETDEWEB)

    Powell, Brian [Clemson Univ., SC (United States); Schlautman, Mark [Clemson Univ., SC (United States); Rao, Linfeng [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Nitsche, Heino [Univ. of California, Berkeley, CA (United States); Gregorich, Kenneth [Univ. of California, Berkeley, CA (United States)

    2016-02-02

    The objective of this research is to examine mechanisms and thermodynamics of actinide sorption to engineered barrier materials (iron (oxyhydr)oxides and bentonite clay) for nuclear waste repositories under high temperature and high ionic strength conditions using a suite of macroscopic and microscopic techniques which will be coupled with interfacial reaction models. Gaining a mechanistic understanding of interfacial processes governing the sorption/sequestration of actinides at mineral-water interfaces is fundamental for the accurate prediction of actinide behavior in waste repositories. Although macroscale sorption data and various spectroscopic techniques have provided valuable information regarding speciation of actinides at solid-water interfaces, significant knowledge gaps still exist with respect to sorption mechanisms and the ability to quantify sorption, particularly at high temperatures and ionic strengths. This objective is addressed through three major tasks: (1) influence of oxidation state on actinide sorption to iron oxides and clay minerals at elevated temperatures and ionic strengths; (2) calorimetric titrations of actinide-mineral suspensions; (3) evaluation of bentonite performance under repository conditions. The results of the work will include a qualitative conceptual model and a quantitative thermodynamic speciation model describing actinide partitioning to minerals and sediments, which is based upon a mechanistic understanding of specific sorption processes as determined from both micro-scale and macroscale experimental techniques. The speciation model will be a thermodynamic aqueous and surface complexation model of actinide interactions with mineral surfaces that is self-consistent with macroscopic batch sorption data, calorimetric and potentiometric titrations, X-ray absorption Spectroscopy (XAS, mainly Extended X-ray Absorption Fine Structure (EXAFS)), and electron microscopy analyses. The novelty of the proposed work lies largely in

  18. Quantification of Cation Sorption to Engineered Barrier Materials Under Extreme Conditions

    International Nuclear Information System (INIS)

    Powell, Brian; Schlautman, Mark; Rao, Linfeng; Nitsche, Heino; Gregorich, Kenneth

    2016-01-01

    The objective of this research is to examine mechanisms and thermodynamics of actinide sorption to engineered barrier materials (iron (oxyhydr)oxides and bentonite clay) for nuclear waste repositories under high temperature and high ionic strength conditions using a suite of macroscopic and microscopic techniques which will be coupled with interfacial reaction models. Gaining a mechanistic understanding of interfacial processes governing the sorption/sequestration of actinides at mineral-water interfaces is fundamental for the accurate prediction of actinide behavior in waste repositories. Although macroscale sorption data and various spectroscopic techniques have provided valuable information regarding speciation of actinides at solid-water interfaces, significant knowledge gaps still exist with respect to sorption mechanisms and the ability to quantify sorption, particularly at high temperatures and ionic strengths. This objective is addressed through three major tasks: (1) influence of oxidation state on actinide sorption to iron oxides and clay minerals at elevated temperatures and ionic strengths; (2) calorimetric titrations of actinide-mineral suspensions; (3) evaluation of bentonite performance under repository conditions. The results of the work will include a qualitative conceptual model and a quantitative thermodynamic speciation model describing actinide partitioning to minerals and sediments, which is based upon a mechanistic understanding of specific sorption processes as determined from both micro-scale and macroscale experimental techniques. The speciation model will be a thermodynamic aqueous and surface complexation model of actinide interactions with mineral surfaces that is self-consistent with macroscopic batch sorption data, calorimetric and potentiometric titrations, X-ray absorption Spectroscopy (XAS, mainly Extended X-ray Absorption Fine Structure (EXAFS)), and electron microscopy analyses. The novelty of the proposed work lies largely in

  19. Forecasting of flowrate under rolling motion flow instability condition based on on-line sequential extreme learning machine

    International Nuclear Information System (INIS)

    Chen Hanying; Gao Puzhen; Tan Sichao; Tang Jiguo; Hou Xiaofan; Xu Huiqiang; Wu Xiangcheng

    2015-01-01

    The coupling of multiple thermal-hydraulic parameters can result in complex flow instability in natural circulation system under rolling motion. A real-time thermal-hydraulic condition prediction is helpful to the operation of systems in such condition. A single hidden layer feedforward neural networks algorithm named extreme learning machine (ELM) is considered as suitable method for this application because of its extremely fast training time, good accuracy and simplicity. However, traditional ELM assumes that all the training data are ready before the training process, while the training data is received sequentially in practical forecasting of flowrate. Therefore, this paper proposes a forecasting method for flowrate under rolling motion based on on-line sequential ELM (OS-ELM), which can learn the data one by one or chunk-by-chunk. The experiment results show that the OS-ELM method can achieve a better forecasting performance than basic ELM method and still keep the advantage of fast training and simplicity. (author)

  20. Nuclear power plant Olkiluoto 3. Containment leakage test under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Fleckenstein, Tobias [TUEV SUED Industrie Service GmbH, Munich (Germany). Measaruement Technology Dept.

    2015-01-15

    Modern nuclear power plants place high demands on the design and execution of safety checks. TUEV SUED supported the containment leakage test for the largest- capacity third generation nuclear power plant in the world - Olkiluoto 3 in Finland. The experts successfully met the challenges presented by exceptional parameters of the project. The containment of Olkiluoto 3 is unique in that the vessel's volume is 80,000 m{sup 3} while measurements were carried out over a period of ten days. To execute the test, 75 temperature and 15 humidity sensors had to be installed and correctly interlinked by more than ten kilometres of cable. These instruments also needed to withstand an absolute pressure of 6 bar, ambient temperatures of 30 C and high levels of humidity. These conditions required comprehensive preparation and a high amount of qualification tests. Parts of the qualifications were carried out at the autoclave system of the Technical University in Munich, Germany, where the project test conditions could be simulated. The software required to determine the tests was developed by TUEV SUED and verified by German's national accreditation body DAkkS under ISO 17025. TUEV SUED enabled the test schedule to continue without delay by analysing all recorded data continuously on site, including pressure, temperature, humidity and leakage mass flow curves. With the comprehensive preparation, data acquisition system recording measurements continuously and the on-time result calculation, all components of the leak-tightness assessment were successfully completed in accordance with requirements.

  1. Modulation of Pleurodeles waltl DNA polymerase mu expression by extreme conditions encountered during spaceflight.

    Directory of Open Access Journals (Sweden)

    Véronique Schenten

    Full Text Available DNA polymerase µ is involved in DNA repair, V(DJ recombination and likely somatic hypermutation of immunoglobulin genes. Our previous studies demonstrated that spaceflight conditions affect immunoglobulin gene expression and somatic hypermutation frequency. Consequently, we questioned whether Polμ expression could also be affected. To address this question, we characterized Polμ of the Iberian ribbed newt Pleurodeles waltl and exposed embryos of that species to spaceflight conditions or to environmental modifications corresponding to those encountered in the International Space Station. We noted a robust expression of Polμ mRNA during early ontogenesis and in the testis, suggesting that Polμ is involved in genomic stability. Full-length Polμ transcripts are 8-9 times more abundant in P. waltl than in humans and mice, thereby providing an explanation for the somatic hypermutation predilection of G and C bases in amphibians. Polμ transcription decreases after 10 days of development in space and radiation seem primarily involved in this down-regulation. However, space radiation, alone or in combination with a perturbation of the circadian rhythm, did not affect Polμ protein levels and did not induce protein oxidation, showing the limited impact of radiation encountered during a 10-day stay in the International Space Station.

  2. The impact of extreme weather conditions on the life of settlers in the Central Russia in X - XVI centuries

    Science.gov (United States)

    Graves, Irina; Nizovtsev, Viacheslav; Erman, Natalia

    2017-04-01

    A special place in the reconstruction of climate dynamics takes an analysis of extraordinary meteorological phenomena. These extreme weather events in the first place impact the functioning of, the rhythm and dynamics of the landscapes and determine not only the features of economy, but also certain aspects of historical development. In the analysis of primary chronicles and published data, along with the direct climatic characteristics (hot, warm, cold, wet, dry, etc.) a lot of attention was paid to abnormal (extreme) natural phenomena and indirect indications of climate variability (floods, crop failures, hunger years, epidemics, etc.). As a result, tables were compiled reflecting climatic basic characteristics and extremes for each year since 900 BC. X-XI centuries was a period of minor climatic optimum - the climate was warmer and drier than the modern one. In addition to higher temperatures (up to 1-3C above than mordern), during this period there were no severe winters. A small amount of summer rainfall has led to a reduction in the number of small water reservoirs and flooding rivers. This is evidenced by Slavic settlements on floodplains of a number of rivers in the Moscow region. It is in this favorable climatic time the way "from the Vikings to the Greeks" was open. Catastrophic natural events had a minimum repeatability. For example, during the X century the Russian chronicles mentioned 41 extreme event, but for the XIII century - 102. Most of the villages and towns were located on the low floodplain terraces of rivers. The main farmland was concentrated there as well. In the "period of contrasts" (XIII - XIV centuries) there was an increase of intra-seasonal climate variability, humidity and widespread reduction in summer temperatures by 1-2C. The number of extreme weather events increased: cold prolonged winters, long rains in summers, cold weather returns in the early summer, early frosts in late summer - early autumn. Such conditions often

  3. Looking for carbonates in the deep Earth: an experimental approach at extreme conditions

    Science.gov (United States)

    Chariton, S.; Bykova, E.; Bykov, M.; Cerantola, V.; Vasiukov, D.; Stekiel, M.; Aprilis, G.; Kupenko, I.; Ismailova, L.; Chumakov, A. I.; Winkler, B.; McCammon, C. A.; Dubrovinsky, L. S.

    2017-12-01

    There is a long list of natural and experimental evidence to support a key role for carbonates in the deep carbon cycle. As potential carriers of carbon in subducted slabs with the possibility to influence redox conditions, carbonates have deservedly been the focus of many high pressure and high temperature experimental studies over the past decade. "How long do they survive after subduction? What form do they transform to? How do they react with their surroundings?" are all important questions. We use many tools to search for carbonates in the deep Earth. Using laser heated diamond anvil cells to generate pressures and temperatures over 100 GPa and 2500 K along with the advanced technology provided by synchrotron facilities, we have been able to study in situ the behavior of various carbonate minerals at conditions of the Earth's mantle. We have particularly focused our interest on transition metal carbonates (Fe, Mn, Co, Zn, Ni)CO3 in order to study the crystal chemistry of calcite-type carbonates using single crystal X-ray diffraction and Raman spectroscopy. Our results show new high-pressure carbonate structures, including either CO3-3or CO4-4 units, that often coexist with complex metal oxides. Combined with carbonate stability fields from the surface to the lower mantle, we investigated the possibility to detect carbonates from seismic data. We determined the elastic wave velocities of plausible carbonate mineral compositions in the (Mg-Fe)CO3 system using Nuclear Inelastic Scattering. Our results show the strong anisotropic behavior of carbonates that could explain anisotropic anomalies observed at transition zone depths and confirm the presence of carbonate reservoirs. The effect of carbonate composition and Fe2+ spin transition, which is completed above 50 GPa, are also well demonstrated. More new carbonate phases and their seismic signatures await to be discovered, and thus experiments continue.

  4. Fabrication of hollow carbon nanospheres introduced with Fe and N species immobilized palladium nanoparticles as catalysts for the semihydrogenation of phenylacetylene under mild reaction conditions

    Science.gov (United States)

    Zhang, Wei; Wang, Fushan; Li, Xinlin; Liu, Yansheng; Liu, Yang; Ma, Jiantai

    2017-05-01

    Palladium nanoparticles immobilized on hollow carbon nanospheres introduced with both Fe and N species, denoted as Pd/Fe-N/C, have been designed as an efficient, heterogeneous, environmentally friendly catalyst for the semihydrogenation of phenylacetylene in liquid-phase under mild conditions (298 K, H2 1 atm) without any additive. A high selectivity towards styrene (higher than 96.2%) was achieved with the total conversion of phenylacetylene within 80 min. The synergistic effect of doped N and Fe with Pd might be an important influence on improving the catalytic performance. Moreover, the Pd/Fe-N/C could be easily recycled by centrifugation and is reusable without obvious decrease of catalytic activity and selectivity. Therefore, the Pd/Fe-N/C nanocatalyst is highly attractive as selective hydrogenation heterogeneous catalyst for important industrial reactions.

  5. Domain wall network as QCD vacuum and the chromomagnetic trap formation under extreme conditions

    International Nuclear Information System (INIS)

    Nedelko, Sergei N.; Voronin, Vladimir E.

    2015-01-01

    The ensemble of Euclidean gluon field configurations represented by the domain wall network is considered. A single domain wall is given by the sine-Gordon kink for the angle between chromomagnetic and chromoelectric components of the gauge field. The domain wall separates the regions with Abelian self-dual and anti-self-dual fields. The network of the domain wall defects is introduced as a combination of multiplicative and additive superpositions of kinks. The character of the spectrum and eigenmodes of color-charged fluctuations in the presence of the domain wall network is discussed. Conditions for the formation of a stable thick domain wall junction (the chromomagnetic trap) during heavy-ion collisions are discussed, and the spectrum of color-charged quasi-particles inside the trap is evaluated. An important observation is the existence of the critical size L c of a single trap stable against gluon tachyonic modes. The size L c is related to the value of gluon condensate left angle g 2 F 2 right angle. The growth of large lumps of merged chromomagnetic traps and the concept of the confinement-deconfinement transition in terms of the ensemble of domain wall networks are outlined. (orig.)

  6. Anaerobic digestion of the microalga Spirulina at extreme alkaline conditions: biogas production, metagenome, and metatranscriptome

    Science.gov (United States)

    Nolla-Ardèvol, Vímac; Strous, Marc; Tegetmeyer, Halina E.

    2015-01-01

    A haloalkaline anaerobic microbial community obtained from soda lake sediments was used to inoculate anaerobic reactors for the production of methane rich biogas. The microalga Spirulina was successfully digested by the haloalkaline microbial consortium at alkaline conditions (pH 10, 2.0 M Na+). Continuous biogas production was observed and the obtained biogas was rich in methane, up to 96%. Alkaline medium acted as a CO2 scrubber which resulted in low amounts of CO2 and no traces of H2S in the produced biogas. A hydraulic retention time (HRT) of 15 days and 0.25 g Spirulina L−1 day−1 organic loading rate (OLR) were identified as the optimal operational parameters. Metagenomic and metatranscriptomic analysis showed that the hydrolysis of the supplied substrate was mainly carried out by Bacteroidetes of the “ML635J-40 aquatic group” while the hydrogenotrophic pathway was the main producer of methane in a methanogenic community dominated by Methanocalculus. PMID:26157422

  7. Dry cooling with night cool storage to enhance solar power plants performance in extreme conditions areas

    International Nuclear Information System (INIS)

    Muñoz, J.; Martínez-Val, J.M.; Abbas, R.; Abánades, A.

    2012-01-01

    Highlights: ► Solar thermo-electric power plants with thermal storage for condenser cooling. ► Technology to mitigate the negative effect on Rankine cycles of the day-time high temperatures in deserts. ► Electricity production augmentation in demand-peak hours by the use of day-night temperature difference. -- Abstract: Solar thermal power plants are usually installed in locations with high yearly average solar radiation, often deserts. In such conditions, cooling water required for thermodynamic cycles is rarely available. Moreover, when solar radiation is high, ambient temperature is very high as well; this leads to excessive condensation temperature, especially when air-condensers are used, and decreases the plant efficiency. However, temperature variation in deserts is often very high, which drives to relatively low temperatures during the night. This fact can be exploited with the use of a closed cooling system, so that the coolant (water) is chilled during the night and store. Chilled water is then used during peak temperature hours to cool the condenser (dry cooling), thus enhancing power output and efficiency. The present work analyzes the performance improvement achieved by night thermal cool storage, compared to its equivalent air cooled power plant. Dry cooling is proved to be energy-effective for moderately high day–night temperature differences (20 °C), often found in desert locations. The storage volume requirement for different power plant efficiencies has also been studied, resulting on an asymptotic tendency.

  8. Biosorption of chromium from electroplating and galvanizing industrial effluents under extreme conditions using Chlorella vulgaris

    Directory of Open Access Journals (Sweden)

    G. Sibi

    2016-07-01

    Full Text Available Hexavalent chromium [Cr(VI] is a toxic oxidized form and an important metal pollutant in the water bodies. Biosorption of chromium(VI offers a potential alternative to conventional metal removal methods. Dried biomass of Chlorella vulgaris was used as biosorbent for the removal of Cr(VI from electroplating and galvanizing industry effluents as a function of biosorbent dosage, contact time, pH, salinity and initial metal ion concentration. Batch experiments were conducted for biosorption and the optimum conditions were 1 g/L biomass, 4 h contact time, pH 2 and 2.893 mS/cm of electrical conductivity. The chromium biosorption was strictly pH dependent with a maximum Cr removal of 63.2 mg/L at pH 2. Highest Cr removal at a concentration of 81.3 mg/L was observed at Electrical conductivity (EC value of 2.893 mS/cm. A comparison of Langmuir and Freundlich isotherm models revealed that Freundlich isotherm model fitted the experimental data based on R2, qmax and standard error values. The results suggest that C. vulgaris biomass could be considered a promising low-cost biosorbent for the removal of Cr(VI from electroplating and galvanizing industry effluents. Keywords: Biosorption, Chlorella vulgaris, Microalgae, Hexavalent chromium

  9. Spirituality and Aging in Place: The Impact of Extreme Climatic Conditions on Domestic Gardening Practice.

    Science.gov (United States)

    Adams, Joanne; Pascal, Jan; Dickson-Swift, Virginia

    2014-12-01

    There is limited research exploring how domestic water restrictions imposed as a result of drought conditions impact upon the lives of independently living older people. Within this age group (60 years plus), the domestic garden frequently forms an intrinsic component of ongoing health and well-being. Gardening practice offers components of both mental and physical activity and, for many older people, leads to emotional and spiritual connection on a number of levels. The capacity of older people to maintain a garden during a period of water restrictions is greatly reduced, and the resulting impact on health and well-being is considerable. A recent study, conducted in south-eastern Australia, aimed to determine the benefits to health and well-being of maintaining a domestic garden for older people and the impact of water restrictions on garden practice. This occurred at a time following a prolonged period of drought and, in central Victoria, a complete ban on outside watering. In-depth qualitative interviews were conducted with 10 gardeners aged between 60 and 83 who had tended their garden over an extended period. The lived experience of gardening was explored through hermeneutic phenomenological analysis. Clear benefits to health and well-being were established, and yet, the essence of this experience lay in the capacity of gardeners to remain connected to their garden despite change. The crisis imposed by ongoing drought and restricted use of water generated a strong impetus for adaptation, resilience and acceptance of change. The spiritual nature of gardening practice clearly emerged and appeared to intensify the experience of gardening and consolidate adaption to change on a number of levels. © The Author(s) 2015.

  10. Men in extreme conditions: some medical and psychological aspects of the Auschwitz concentration camp.

    Science.gov (United States)

    Radil-Weiss, T

    1983-08-01

    The second world war ended many years ago. Most of those who survived the stay at the German concentration camp at Auschwitz have already died of the consequences of their imprisonment; those still alive are already in the last third of their life. Is there any point in returning to the experiences of those days? Consideration of the mental hygiene of former prisoners cautions us that perhaps we should not do it. But consideration of the general interest holds that we are not entitled to ignore any knowledge that can contribute to social development--including medicine and psychology--even if acquired under unspeakably awful conditions. In addition, since the war new generations have grown up that play an increasingly significant role in various spheres of life but have little concrete information about those events; they can neither rationally nor emotionally understand how the horrors connected with fascism and the war could have happened. In a sense it is encouraging that they cannot grasp such inhuman behavior; nevertheless, we must adhere to the following motto: "Nothing must be forgotten, nobody will be forgotten." We owe it to those millions who did not survive--both the victims of the Holocaust and those who fought against it. These are arguments in favor of returning to the facts that are ineffaceably recorded somewhere in our memories. In doing so, however, we must remember that at times we are revisiting experiences of a boy of 14 as recalled by a 50-year-old man. The material below, examining the medical as well as psychological aspects of imprisonment at Auschwitz, is based on my own memories, as an adolescent imprisoned at Auschwitz. I have tried to move from this individual account to more general statements, although the methodological apparatus on which scientific analysis is usually based is absent.

  11. The family as a determinant of stunting in children living in conditions of extreme poverty: a case-control study

    Directory of Open Access Journals (Sweden)

    Doubova Svetlana V

    2004-11-01

    Full Text Available Abstract Background Malnutrition in children can be a consequence of unfavourable socioeconomic conditions. However, some families maintain adequate nutritional status in their children despite living in poverty. The aim of this study was to ascertain whether family-related factors are determinants of stunting in young Mexican children living in extreme poverty, and whether these factors differ between rural or urban contexts. Methods A case-control study was conducted in one rural and one urban extreme poverty level areas in Mexico. Cases comprised stunted children aged between 6 and 23 months. Controls were well-nourished children. Independent variables were defined in five dimensions: family characteristics; family income; household allocation of resources and family organisation; social networks; and child health care. Information was collected from 108 cases and 139 controls in the rural area and from 198 cases and 211 controls in the urban area. Statistical analysis was carried out separately for each area; unconditional multiple logistic regression analyses were performed to obtain the best explanatory model for stunting. Results In the rural area, a greater risk of stunting was associated with father's occupation as farmer and the presence of family networks for child care. The greatest protective effect was found in children cared for exclusively by their mothers. In the urban area, risk factors for stunting were father with unstable job, presence of small social networks, low rate of attendance to the Well Child Program activities, breast-feeding longer than six months, and two variables within the family characteristics dimension (longer duration of parents' union and migration from rural to urban area. Conclusions This study suggests the influence of the family on the nutritional status of children under two years of age living in extreme poverty areas. Factors associated with stunting were different in rural and urban communities

  12. Air-cooled LiBr-water absorption chillers for solar air conditioning in extremely hot weathers

    International Nuclear Information System (INIS)

    Kim, D.S.; Infante Ferreira, C.A.

    2009-01-01

    A low temperature-driven absorption cycle is theoretically investigated for the development of an air-cooled LiBr-water absorption chiller to be combined with low-cost flat solar collectors for solar air conditioning in hot and dry regions. The cycle works with dilute LiBr-water solutions so that risk of LiBr crystallization is less than for commercially available water-cooled LiBr-water absorption chillers even in extremely hot ambient conditions. Two-phase heat exchangers in the system were modelled taking account of the heat and mass transfer resistances in falling film flows by applying the film theory in thermal and concentration boundary layers. Both directly and indirectly air-cooled chillers were modelled by properly combining component models and boundary conditions in a matrix system and solved with an algebraic equation solver. Simulation results predict that the chillers would deliver chilled water around 7.0 deg. C with a COP of 0.37 from 90 deg. C hot water under 35 deg. C ambient condition. At 50 deg. C ambient temperature, the chillers retained about 36% of their cooling power at 35 deg. C ambient. Compared with the directly air-cooled chiller, the indirectly air-cooled chiller presented a cooling power performance reduction of about 30%

  13. Kinetics of Materials at Extreme Conditions: Understanding the Time Dependent Approach to Equilibrium at MaRIE

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, R. G. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Mcnabb, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Kumar, M. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Eggert, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Borg, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Cerreta, E. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Dattelbaum, D. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Fried, L. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Greeff, C. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Stolken, J. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2017-04-21

    The National Nuclear Security Agency has recently recognized that a long-term need exists to establish a stronger scientific basis for the assessment and qualification of materials and manufacturing processes for the nuclear stockpile and other national security applications. These materials may have undergone substantial changes with age, or may represent new materials that are being introduced because of difficulties associated with reusing or recreating materials used in original stockpile components. Also, with advancements in manufacturing methods, the NNSA anticipates opportunities for an enhanced range of control over fabricated components, an enhanced pace of materials development, and enhanced functionality. The development of qualification standards for these new materials will require the ability to understand and control material characteristics that affect both mechanical and dynamic performance. A unique aspect for NNSA is that the performance requirements for materials are often set by system hydrodynamics, and these materials must perform in extreme environments and loading conditions. Thus, the scientific motivation is to understand “Matter-Radiation Interactions in Extremes (MaRIE).”

  14. Properties of a planar electric double layer under extreme conditions investigated by classical density functional theory and Monte Carlo simulations.

    Science.gov (United States)

    Zhou, Shiqi; Lamperski, Stanisław; Zydorczak, Maria

    2014-08-14

    Monte Carlo (MC) simulation and classical density functional theory (DFT) results are reported for the structural and electrostatic properties of a planar electric double layer containing ions having highly asymmetric diameters or valencies under extreme concentration condition. In the applied DFT, for the excess free energy contribution due to the hard sphere repulsion, a recently elaborated extended form of the fundamental measure functional is used, and coupling of Coulombic and short range hard-sphere repulsion is described by a traditional second-order functional perturbation expansion approximation. Comparison between the MC and DFT results indicates that validity interval of the traditional DFT approximation expands to high ion valences running up to 3 and size asymmetry high up to diameter ratio of 4 whether the high valence ions or the large size ion are co- or counter-ions; and to a high bulk electrolyte concentration being close to the upper limit of the electrolyte mole concentration the MC simulation can deal with well. The DFT accuracy dependence on the ion parameters can be self-consistently explained using arguments of liquid state theory, and new EDL phenomena such as overscreening effect due to monovalent counter-ions, extreme layering effect of counter-ions, and appearance of a depletion layer with almost no counter- and co-ions are observed.

  15. Extreme storm surges in the south of Brazil: atmospheric conditions and shore erosion

    Directory of Open Access Journals (Sweden)

    Cláudia Klose Parise

    2009-09-01

    Full Text Available The region under study is regularly subject to the occurrence of storms associated with frontal systems and extratropical cyclones, since it is located near one of the cyclogenetic regions in South America. These storms can generate storm surges that cause anomalous high sea level rises on Cassino Beach. The use of reanalysis data along with an efficient technique for the location of the cyclone, using a vorticity threshold, has provided a new classification based upon the trajectories of events that produce positive sea level variation. Three patterns have been identified: 1 Cyclogenesis to the south of Argentina with displacement to the east and a trajectory between 47.5ºS and 57.5ºS; 2 Cyclogenesis to the south of Uruguay with displacement to the east and a trajectory between 35ºS and 42.5ºS; and 3 Cyclogenesis to the south of Uruguay with displacement to the southeast and a trajectory between 35ºS and 57.5ºS. Maximum water level elevation above the mean sea level and beach erosion were associated, respectively, with winter and summer storms. Cassino beach displayed a seasonal morphological behavior, with short periods of episodic erosion associated with winter storm events followed by long periods of accretion characterized by the dominance of fair weather conditions.Marés meteorológicas que geram sobre-elevações do nível do mar são freqüentes na costa do Rio Grande do Sul e respondem às variações ocorridas na atmosfera. Torna-se importante, dessa maneira, definir padrões meteorológicos sinóticos responsáveis por gerar eventos de marés meteorológicas intensas na Praia do Cassino como objetivo desse trabalho. O uso de dados de reanálise associados a uma técnica eficiente de localização do ciclone, aplicando o conceito de vorticidade, permitiu definir uma nova classificação com base na trajetória de ciclones extratropicais responsáveis pela subida do nível do mar. Três padrões de trajetórias foram

  16. Homogenous UV/periodate process in treatment of p-nitrophenol aqueous solutions under mild operating conditions.

    Science.gov (United States)

    Saien, Javad; Fallah Vahed Bazkiaei, Marzieh

    2018-07-01

    Aqueous solutions of p-nitrophenol (PNP) were treated with UV-activated potassium periodate (UV/KPI) in an efficient photo-reactor. Either periodate or UV alone had little effect; however, their combination led to a significant degradation and mineralization. The response surface methodology was employed for design of experiments and optimization. The optimum conditions for treatment of 30 mg/L of the substrate were determined as [KPI] = 386.3 mg/L, pH = 6.2 and T = 34.6°C, under which 79.5% degradation was achieved after 60 min. Use of 25 and 40 kHz ultrasound waves caused the degradation to enhance to 88.3% and 92.3%, respectively. The intermediates were identified by gas chromatography-mass spectroscopy analysis, leading to propose the reaction pathway. The presence of water conventional bicarbonate, chloride, sulfate and nitrate anions caused unfavorable effects in efficiency. Meanwhile, the kinetic study showed that PNP degradation follows a pseudo-first-order reaction and the activation energy was determined. The irradiation energy consumption required for one order of magnitude degradation was estimated as 11.18 kWh/m 3 . Accordingly, comparison with the previously reported processes showed the superiority of PNP treatment with the employed process.

  17. Effects of anthropogenic heat due to air-conditioning systems on an extreme high temperature event in Hong Kong

    Science.gov (United States)

    Wang, Y.; Li, Y.; Di Sabatino, S.; Martilli, A.; Chan, P. W.

    2018-03-01

    Anthropogenic heat flux is the heat generated by human activities in the urban canopy layer, which is considered the main contributor to the urban heat island (UHI). The UHI can in turn increase the use and energy consumption of air-conditioning systems. In this study, two effective methods for water-cooling air-conditioning systems in non-domestic areas, including the direct cooling system and central piped cooling towers (CPCTs), are physically based, parameterized, and implemented in a weather research and forecasting model at the city scale of Hong Kong. An extreme high temperature event (June 23-28, 2016) in the urban areas was examined, and we assessed the effects on the surface thermal environment, the interaction of sea-land breeze circulation and urban heat island circulation, boundary layer dynamics, and a possible reduction of energy consumption. The results showed that both water-cooled air-conditioning systems could reduce the 2 m air temperature by around 0.5 °C-0.8 °C during the daytime, and around 1.5 °C around 7:00-8:00 pm when the planetary boundary layer (PBL) height was confined to a few hundred meters. The CPCT contributed around 80%-90% latent heat flux and significantly increased the water vapor mixing ratio in the atmosphere by around 0.29 g kg-1 on average. The implementation of the two alternative air-conditioning systems could modify the heat and momentum of turbulence, which inhibited the evolution of the PBL height (a reduction of 100-150 m), reduced the vertical mixing, presented lower horizontal wind speed and buoyant production of turbulent kinetic energy, and reduced the strength of sea breeze and UHI circulation, which in turn affected the removal of air pollutants. Moreover, the two alternative air-conditioning systems could significantly reduce the energy consumption by around 30% during extreme high temperature events. The results of this study suggest potential UHI mitigation strategies and can be extended to

  18. Development and performance test of a system available for generating multiple extreme conditions for neutron scattering experiments

    International Nuclear Information System (INIS)

    Kawano, Shinji; Fukui, Susumu; Moriai, Atsushi; Ohtomo, Akitoshi; Ichimura, Shigeki; Onodera, Akifumi; Amita, F.; Katano, Susumu

    1998-01-01

    We have developed unique system available for controlling sample environment during the neutron scattering experiments. The system can simultaneously generate triple extreme conditions of low temperature, high magnetic field and high pressure. The system consists of: (i) a liquid-helium cryostat variable for sample temperature from 1.7 K to 200 K, (ii) a superconducting magnet providing a vertical field up to ±5 T with an antisymmetric split-coil geometry for polarized-beam experiments, and (iii) a non-magnetic piston-cylinder high-pressure cell designed with the aim of generating hydrostatic pressure up to 2.5 GPa. In the presentation, we will report the outline of the system and some results of performance tests at KURRI and JRR-3M of JAERI. (author)

  19. A comparison study of the two-bladed partial pitch turbine during normal operation and an extreme gust conditions

    International Nuclear Information System (INIS)

    Kim, T; Petersen, M M; Larsen, T J

    2014-01-01

    This paper shows the load comparisons between the numerical simulation and the full-scale load measurement data. First part of this paper includes the comparisons of statistic load in terms of maximum, mean, and minimum values for the selected normal operation cases. The blade root bending moments and tower top bending moments are compared. Second part of this paper introduces the dynamic response comparisons during an extreme wind gust condition where the wind speed changed approximately 10 m/s during three seconds. The rotor speed and blade root flapwise and edgewise bending moment are compared. The nonlinear aeroelastic simulation code HAWC2 is used for the simulations. A very fine agreement between the simulated and the full-scale measured loads is seen for the both comparisons

  20. Analyses of crystal field and exchange interaction of Dy3Ga5O12 under extreme conditions

    International Nuclear Information System (INIS)

    Wang Wei; Qi Xin; Yue Yuan

    2011-01-01

    This paper theoretically investigates the effects of crystal field and exchange interaction field on magnetic properties in dysprosium gallium garnet under extreme conditions (low temperatures and high magnetic fields) based on quantum theory. Here, five sets of crystal field parameters are discussed and compared. It demonstrates that, only considering the crystal field effect, the experiments can not be successfully explained. Thus, referring to the molecular field theory, an effective exchange field associated with the Dy—Dy exchange interaction is further taken into account. Under special consideration of crystal field and the exchange interaction field, it obtains an excellent agreement between the theoretical results and experiments, and further confirms that the exchange interaction field between rare-earth ions has great importance to magnetic properties in paramagnetic rare-earth gallium garnets. (condensed matter: electronic structure, electrical, magnetic, and optical properties)

  1. HERCULES Specialized Course on Synchrotron radiation and neutrons for extreme conditions studies - HSC12 - slides of the presentations

    International Nuclear Information System (INIS)

    Daniel, I.; Itie, J.P.; Meersman, F.; Jacobs, J.; Hantsetters, K. de; Syassen, K.; Krisch, M.; Mezouar, M.; Mac Millan, P.F.; Salmon, P.; Klotz, S.; Pascarelli, S.; Hansen, T.C.

    2011-01-01

    The purpose of this Hercules Specialized Course (HSC12) is to give the participants an introduction to high pressure research at large experimental facilities such as the synchrotron and the neutron reactor. The basic principles of synchrotron radiation and neutrons techniques at extreme conditions of pressure have been illustrated. Cross-disciplinary examples in a representative range of scientific areas, covering fundamental physics, earth and planetary science, chemistry and material science have been dealt with. Most presentations are dedicated to X-ray diffraction, X-ray absorption and neutron scattering of materials (solids, liquids or glasses) at high pressure. Several presentations deal with the experimental set-up and especially the preparation of the diamond anvil. This document is made up of the slides of the presentations. (A.C.)

  2. Reliability of offshore wind power production under extreme wind conditions. Deliverable D 9.5. Work Package 9: Electrical grid

    DEFF Research Database (Denmark)

    Cutululis, Nicolaos Antonio; Zeni, Lorenzo

    years, with each year simulated with five random seeds, leading to a total of 25 annual wind power time series for six large offshore wind farms, summing up to a little over 330 wind turbines. Two storm control strategies were used. The analysis involved several aspects inspired from reliability studies....... The aspects investigated are storm events occurrences and durations, storm control strategy impact on the capacity factor (lost production), the loss of production (power produced from wind drops below a certain threshold due to high wind speeds and storm controller) and finally, the wind power production......Reliability of offshore wind production under extreme wind conditions was investigated in this report. The wind power variability from existing and future large offshore wind farms in Western Denmark were simulated using the Correlated Wind model developed at Risø. The analysis was done for five...

  3. Effect of multiple-feedstock strategy on the economic and environmental performance of thermochemical ethanol production under extreme weather conditions

    International Nuclear Information System (INIS)

    Kou, Nannan; Zhao, Fu

    2011-01-01

    Current US transportation sector mainly relies on liquid hydrocarbons derived from petroleum and about 60% of the petroleum consumed is from areas where supply may be disturbed by regional instability. This has led to serious concerns on energy security and global warming. To address these issues, numerous alternative energy carriers have been proposed. Among them, second generation biofuel is one of the most promising technologies. Gasification-based thermochemical conversion will bring flexibility to both feedstock and production sides of a plant, thus presents an attractive technical route to address both the energy security and global warming concerns. In this paper, thermochemical ethanol production using multiple-feedstock (corn stover, municipal solid waste, and wood chips) is simulated using Aspen Plus and compared with the single-feedstock scenario, in terms of economic performances, life cycle greenhouse gas (GHG) emissions and survivability under extreme weather conditions. For a hypothetical facility in southwest Indiana it is found that multiple-feedstock strategy improves the net present value by 18% compared to single-feedstock strategy. This margin is increased to 57% when effects of extreme weather conditions on feedstock supply are considered. Moreover, multiple-feedstock fuel plant has no potential risk of bankruptcy during the payback period, while single-feedstock fuel plant has a 75% chance of bankruptcy. Although the multiple-feedstock strategy has 26% more GHG emission per liter of ethanol produced than the single-feedstock strategy, the trend is reversed if feedstock supply disruption is taken into account. Thus the idea of multiple-feedstock strategy is proposed to the future thermo chemical biofuel plants.

  4. Technology-derived storage solutions for stabilizing insulin in extreme weather conditions I: the ViViCap-1 device.

    Science.gov (United States)

    Pfützner, Andreas; Pesach, Gidi; Nagar, Ron

    2017-06-01

    Injectable life-saving drugs should not be exposed to temperatures 30°C/86°F. Frequently, weather conditions exceed these temperature thresholds in many countries. Insulin is to be kept at 4-8°C/~ 39-47°F until use and once opened, is supposed to be stable for up to 31 days at room temperature (exception: 42 days for insulin levemir). Extremely hot or cold external temperature can lead to insulin degradation in a very short time with loss of its glucose-lowering efficacy. Combined chemical and engineering solutions for heat protection are employed in ViViCap-1 for disposable insulin pens. The device works based on vacuum insulation and heat consumption by phase-change material. Laboratory studies with exposure of ViViCap-1 to hot outside conditions were performed to evaluate the device performance. ViViCap-1 keeps insulin at an internal temperature phase-change process and 'recharges' the device for further use. ViViCap-1 performed within its specifications. The small and convenient device maintains the efficacy and safety of using insulin even when carried under hot weather conditions.

  5. Habitability in Extreme Conditions

    Science.gov (United States)

    de Lobkowicz, Ysaline; de Crombrugghe, Guerric; Le Maire, Victor; Jago, Alban; Denies, Jonathan; van Vynckt, Delphine; Reydams, Marc; Mertens, Alexandre

    A manned space mission could be perfectly prepared in terms of sciences and technologies, but without a good habitat, a place where the needs of the crew are respected, this isolation and confinement can turn into a nightmare. There is the limitation of engineering: it is more than important to take care about architecture, when human lives are part of the experiment. The goal of the research is the analysis of the hard life of isolation and confinement in Mars' hostile environment and how architecture is a way to improve it. The objective is to place the human in the middle of the analysis. What does a person really need? Therefore Maslow's idea, the pyramid of primary needs, gives us the hierarchy to follow: first survival, food and beverage, then sleep, and only then protection, social activities and work. [1] No more luxury. If all these aspects are respected, a human is able to survive, like it did since so many years. The idea is that each of these main activities has to be related to a different type of space, to provide variability in this close environment. For example, work and relaxing areas have to be separated; a human being needs time for himself, without concentration. A workspace and a relaxing area have a different typology, different colours and lighting, dimensions, furniture. This has also to be respected in a spacecraft. For this research, different sources are used, mainly in the psychological aspect, which is the most important. [2] Therefore questionnaires, interviews, diaries of past expeditions are full of treasures. We do not have to search too far: on earth; polar expeditions, submarines, military camps, etc., give a lot of information. Some very realistic simulations, as on the Mars Desert Research Station (MDRS), will also be used as material: a good analysis of the defaults and well-organized part of the station can conduct to important conclusions. [3] A found analysis and a well-designed habitat are considerable keys for the success of the mission. References: [1] A. Maslow (1943) Theory of Human Motivation [2] J. Stuster (1996) Bold Endeavors, Lessons from Polar and Space Exploration [3] Mars Society, Mars Desert Research Station in Utah

  6. Hexafluorobenzene under Extreme Conditions.

    Science.gov (United States)

    Pravica, Michael; Sneed, Daniel; Wang, Yonggang; Smith, Quinlan; White, Melanie

    2016-03-17

    We report the results from three high pressure experiments on hexafluorobenzene (C6F6). In the first experiment, Raman spectra were recorded up to 34.4 GPa. A phase transition from I → II was observed near 2 GPa. Near 8.8 GPa, a phase transition to an unreported phase (III) commenced. Above 20.6 GPa, yet another phase was observed (IV). Pressure cycling was employed to determine that, below 25.6 GPa, all pressure-induced alterations were reversible. However, at pressures above 20 GPa, dramatic spectral changes and broadening were observed at 25.6 and 34.4 GPa. The sample irreversibly changed into a soft solid with waxlike consistency when pressure was reduced to ambient and was recoverable. In the second experiment, IR spectra were collected up to 14.6 GPa. The phase transition (II → III) near 8.8 GPa was confirmed. An angular dispersive X-ray diffraction experiment was conducted to 25.6 GPa. Phase transitions above 1.4 GPa (I → II), above 5.5 GPa (II → III), above 10 GPa (III → IV), and above 15.5 GPa (IV → V) were observed. Near 25.6 GPa, long-range crystalline order was lost as the X-ray diffraction spectrum presented evidence of an amorphous solid.

  7. Different MK-801 administration schedules induce mild to severe learning impairments in an operant conditioning task: role of buspirone and risperidone in ameliorating these cognitive deficits.

    Science.gov (United States)

    Rapanelli, Maximiliano; Frick, Luciana Romina; Bernardez-Vidal, Micaela; Zanutto, Bonifacio Silvano

    2013-11-15

    Blockade of N-methyl-d-aspartate receptor (NMDA) by the noncompetitive NMDA receptor (NMDAR) antagonist MK-801 produces behavioral abnormalities and alterations in prefrontal cortex (PFC) functioning. Due to the critical role of the PFC in operant conditioning task learning, we evaluated the effects of acute, repeated postnatal injections of MK-801 (0.1mg/kg) on learning performance. We injected Long-Evans rats i.p. with MK-801 (0.1mg/kg) using three different administration schedules: injection 40 min before beginning the task (during) (n=12); injection twice daily for six consecutive days prior to beginning the experimental procedures (prior) (n=12); or twice daily subcutaneous injections from postnatal day 7 to 11 (postnatal) (n=12). Next, we orally administered risperidone (serotonin receptor 2A and dopamine receptor 2 antagonist, 1mg/kg) or buspirone (serotonin receptor 1A partial agonist, 10mg/kg) to animals treated with the MK-801 schedule described above. The postnatal and prior administration schedules produced severe learning deficits, whereas injection of MK-801 just before training sessions had only mild effects on acquisition of an operant conditioning. Risperidone was able to reverse the detrimental effect of MK-801 in the animals that were treated with MK-801 during and prior training sessions. In contrast, buspirone was only effective at mitigating the cognitive deficits induced by MK-801 when administered during the training procedures. The data demonstrates that NMDA antagonism disrupts basic mechanisms of learning in a simple PFC-mediated operant conditioning task, and that buspirone and risperidone failed to attenuate the learning deficits when NMDA neurotransmission was blocked in the early stages of the postnatal period. Copyright © 2013 Elsevier B.V. All rights reserved.

  8. Surface grafting of poly(ethylene glycol) onto poly(acrylamide-co-vinyl amine) cross-linked films under mild conditions.

    Science.gov (United States)

    Yamamoto, Y; Sefton, M V

    1998-01-01

    Poly(ethylene glycol) (PEG) was grafted onto poly(acrylamide-co-vinyl amine) (poly(AM-co-VA)) film using tresylated PEG (TPEG) at 37 degrees C in aqueous buffers (pH 7.4) with a view to surface-modifying microencapsulated mammalian cells. Poly(AM-co-VA) film was synthesized by Hofmann degradation of a cross-linked poly(acrylamide) film. Conversion to vinyl amine on the surface of the film was approximately 50%, but bulk conversion was not observed; surface specificity was thought to be the result of cleavage of aminated polymer chains at the surface due to chain scission. Reaction between primary amine and TPEG gave a graft yield of 2 mol% (based on XPS) with respect to available surface amine groups, equivalent to 54 mol% ethylene oxide based on monomer units. Physical adsorption of non-activated polymer was done under identical conditions as a control and the difference in oxygen content was significant compared to TPEG. The type of buffer agent and buffer concentration did not influence graft yields. This graft reaction, which was completed in as little as 2 h was considered to be mild enough to be used for a surface modification of microcapsules containing cells without affecting their viability. Such a surface modification technique may prove to be a useful means of enhancing the biocompatibility of microcapsules (or any tissue engineering construct) even after cell encapsulation or seeding.

  9. The Community Balance and Mobility Scale: A Pilot Study Detecting Impairments in Military Service Members With Comorbid Mild TBI and Psychological Health Conditions.

    Science.gov (United States)

    Pape, Marcy M; Williams, Kathy; Kodosky, Paula N; Dretsch, Michael

    2016-01-01

    To compare the capacity of the Community Balance and Mobility Scale (CB&M) to identify balance and mobility deficits in Service Members (SMs) with mild traumatic brain injury and comorbid psychological health conditions (mTBI/PH) to other commonly used balance assessments. A clinical research institute that provides a 4-week, outpatient, interdisciplinary program for active-duty SMs with mTBI/PH. A nonrandomized, cross-sectional design that compared multiple measures between 2 groups-active duty SMs with (n = 8) and without (n = 8) the dual diagnosis of mTBI/PH. Gait speed, Activities-specific Balance Confidence scale (ABC), Functional Gait Assessment (FGA), and CB&M to assess functional balance among the community-dwelling, TBI population. Across all measures, the mTBI/PH group performed significantly worse (P ≤ .01) with the exception of the FGA. The abilities of all objective measures to distinguish participants with mTBI/PH from healthy controls ranged from fair to excellent (area under the curve [AUC] = 0.66-0.94). However, the CB&M showed the largest group differences in effect size (d = 2.6) and had the highest discriminate ability (AUC = 0.98; sensitivity 100%; specificity 88%). The CB&M appears to have higher sensitivity and specificity than other measures of balance in SMs with mTBI/PH. A higher cut score for the CB&M is needed for this population.

  10. Evaluating the clinical utility of the Validity-10 for detecting amplified symptom reporting for patients with mild traumatic brain injury and comorbid psychological health conditions.

    Science.gov (United States)

    Dretsch, Michael N; Williams, Kathy; Staver, Tara; Grammer, Geoffrey; Bleiberg, Joseph; DeGraba, Thomas; Lange, Rael T

    2017-01-01

    The objective of this study was to compare the Validity-10 scale with the PAI Negative Impression Management Scale (PAI-NIM) for detecting exaggerated symptom reporting in active-duty military service members (SMs) admitted with unremitting mild TBI symptoms and comorbid psychological health conditions (mTBI/PH). Data were analyzed from 254 SMs who completed the Neurobehavioral Symptom Inventory (NSI) and Personality Assessment Inventory (PAI) as a part of a larger battery of self-report symptom scales upon admission to the intensive-outpatient TBI treatment program at a military medical center. Symptom exaggeration was operationalized using the PAI Negative Impression Management Scale (PAI-NIM). A PAI-NIM score of ≥73 was categorized as positive for symptom exaggeration (SVTpos), while a lower score was categorized as negative for symptom exaggeration (SVTneg). SMs in the SVTpos group (n = 34) had significantly higher scores (p ≤ .004) on the PAI clinical scales as well as on the NSI total score (range: d = 0.59-1.91) compared to those who were SVTneg (n = 220). The optimal cut-score for the NSI Val-10 scale to identify possible symptom exaggeration was ≥26 (sensitivity = .29, specificity = .95, PPP = .74, NPP = .71). In patients suffering from mTBI/PH, the Validity-10 requires a higher cut-score than previously reported to be useful as a metric of exaggerated symptom reporting.

  11. The need of the change of the conceptualisation of hydrologic processes under extreme conditions – taking reference evapotranspiration as an example

    Directory of Open Access Journals (Sweden)

    S. Liu

    2015-06-01

    Full Text Available What a hydrological model displays is the relationships between the output and input in daily, monthly, yearly and other temporal scales. In the case of climate change or other environment changes, the input of the hydrological model may show a gradual or abrupt change. There have been numerous documented studies to explore the response of output of the hydrological models to the change of the input with scenario simulation. Most of the studies assumed that the conceptualisation of hydrologic processes will remain, which may be true for the gradual change of the input. However, under extreme conditions the conceptualisation of hydrologic processes may be completely changed. Taking an example of the Allen's formula to calculate crop reference evapotranspiration (ET0 as a simple hydrological model, we analyze the alternation of the extreme in ET0 from 1955 to 2012 at the Chongling Experimental Station located in Hebei Province, China. The relationships between ET0 and the meteorological factors for the average values, minimum (maximum values at daily, monthly and annual scales are revealed. It is found the extreme of the output can follow the extreme of the input better when their relationship is more linear. For non-liner relationship, the extreme of the input cannot at all be reflected from the extreme of the output. Relatively, extreme event at daily scale is harder to be shown than that at monthly scale. The result implicates that a routine model may not be able to catch the response to extreme events and it is even more so as we extrapolate models to higher temperature/CO2 conditions in the future. Some possible choices for the improvements are suggested for predicting hydrological extremes.

  12. Desiccation and Mortality Dynamics in Seedlings of Different European Beech (Fagus sylvatica L.) Populations under Extreme Drought Conditions

    Science.gov (United States)

    Bolte, Andreas; Czajkowski, Tomasz; Cocozza, Claudia; Tognetti, Roberto; de Miguel, Marina; Pšidová, Eva; Ditmarová, Ĺubica; Dinca, Lucian; Delzon, Sylvain; Cochard, Hervè; Ræbild, Anders; de Luis, Martin; Cvjetkovic, Branislav; Heiri, Caroline; Müller, Jürgen

    2016-01-01

    European beech (Fagus sylvatica L., hereafter beech), one of the major native tree species in Europe, is known to be drought sensitive. Thus, the identification of critical thresholds of drought impact intensity and duration are of high interest for assessing the adaptive potential of European beech to climate change in its native range. In a common garden experiment with one-year-old seedlings originating from central and marginal origins in six European countries (Denmark, Germany, France, Romania, Bosnia-Herzegovina, and Spain), we applied extreme drought stress and observed desiccation and mortality processes among the different populations and related them to plant water status (predawn water potential, ΨPD) and soil hydraulic traits. For the lethal drought assessment, we used a critical threshold of soil water availability that is reached when 50% mortality in seedling populations occurs (LD50SWA). We found significant population differences in LD50SWA (10.5–17.8%), and mortality dynamics that suggest a genetic difference in drought resistance between populations. The LD50SWA values correlate significantly with the mean growing season precipitation at population origins, but not with the geographic margins of beech range. Thus, beech range marginality may be more due to climatic conditions than to geographic range. The outcome of this study suggests the genetic variation has a major influence on the varying adaptive potential of the investigated populations. PMID:27379105

  13. Communication: A novel method for generating molecular mixtures at extreme conditions: The case of hydrogen and oxygen

    International Nuclear Information System (INIS)

    Pravica, Michael; Sneed, Daniel; White, Melanie; Wang, Yonggang

    2014-01-01

    We have successfully created a segregated mixture of hydrogen and oxygen at high pressure in a diamond anvil cell using hard x-ray photochemistry. A keyhole (two holes connected by an opening) sample chamber was created in a metallic gasket to support two segregated powders of ammonia borane and potassium perchlorate, respectively, in each hole at a pressure of ∼5.0 GPa. Both holes were separately irradiated with synchrotron hard x-rays to release molecular oxygen and molecular hydrogen, respectively. Upon irradiation of the first KClO 4 -containing hole, solid reddish-orange O 2 appeared in the region of irradiation and molecular oxygen was found to diffuse throughout the entire sample region. The second ammonia borane-containing hole was then irradiated and H 2 was observed to form via Raman spectroscopy. Water also was observed in the ammonia borane-containing hole and possibly (in the form of ice VII) in the second hole. This unique experiment demonstrates the ability to easily create solid mixtures of simple molecular systems via x-ray irradiation and then react them via further irradiation which will aid the study of chemistry under extreme conditions

  14. 360°-View of Quantum Theory and Ab Initio Simulation at Extreme Conditions: 2014 Sanibel Symposium

    International Nuclear Information System (INIS)

    Cheng, Hai-Ping

    2016-01-01

    The Sanibel Symposium 2014 was held February 16-21, 2014, at the King and Prince, St. Simons Island, GA. It was successful in bringing condensed-matter physicists and quantum chemists together productively to drive the emergence of those specialties. The Symposium had a significant role in preparing a whole generation of quantum theorists. The 54th Sanibel meeting looked to the future in two ways. We had 360°-View sessions to honor the exceptional contributions of Rodney Bartlett (70), Bill Butler (70), Yngve Öhrn (80), Fritz Schaefer (70), and Malcolm Stocks (70). The work of these five has greatly impacted several generations of quantum chemists and condensed matter physicists. The ''360°'' is the sum of their ages. More significantly, it symbolizes a panoramic view of critical developments and accomplishments in theoretical and computational chemistry and physics oriented toward the future. Thus, two of the eight 360°-View sessions focused specifically on younger scientists. The 360°-View program was the major component of the 2014 Sanibel meeting. Another four sessions included a sub-symposium on ab initio Simulations at Extreme Conditions, with focus on getting past the barriers of present-day Born-Oppenheimer molecular dynamics by advances in finite-temperature density functional theory, orbital-free DFT, and new all-numerical approaches.

  15. Alginate Adsorbent Immobilization Technique Promotes Biobutanol Production by Clostridium acetobutylicum Under Extreme Condition of High Concentration of Organic Solvent

    Directory of Open Access Journals (Sweden)

    Zhuoliang Ye

    2018-05-01

    Full Text Available In Acetone-Butanol-Ethanol fermentation, bacteria should tolerate high concentrations of solvent products, which inhibit bacteria growth and limit further increase of solvents to more than 20 g/L. Moreover, this limited solvent concentration significantly increases the cost of solvent separation through traditional approaches. In this study, alginate adsorbent immobilization technique was successfully developed to assist in situ extraction using octanol which is effective in extracting butanol but presents strong toxic effect to bacteria. The adsorbent improved solvent tolerance of Clostridium acetobutylicum under extreme condition of high concentration of organic solvent. Using the developed technique, more than 42% of added bacteria can be adsorbed to the adsorbent. Surface area of the adsorbent was more than 10 times greater than sodium alginate. Scanning electron microscope image shows that an abundant amount of pore structure was successfully developed on adsorbents, promoting bacteria adsorption. In adsorbent assisted ABE fermentation, there was 21.64 g/L butanol in extracting layer compared to negligible butanol produced with only the extractant but without the adsorbent, for the reason that adsorbent can reduce damaging exposure of C. acetobutylicum to octanol. The strategy can improve total butanol production with respect to traditional culture approach by more than 2.5 fold and save energy for subsequent butanol recovery, which effects can potentially make the biobutanol production more economically practical.

  16. Aqueous hydrodechlorination of 4-chlorophenol over an Rh/reduced graphene oxide synthesized by a facile one-pot solvothermal process under mild conditions

    International Nuclear Information System (INIS)

    Ren, Yanlin; Fan, Guangyin; Wang, Chenyu

    2014-01-01

    Graphical abstract: The Rh nanoparticles/reduced graphene oxide (Rh NPs/RGO) nanocatalyst synthesized by a solvothermal technique showed high activity and stability for the hydrodechlorination of 4-chlorophenol under mild conditions. - Highlights: • Rh/RGO was synthesized through a one-pot polyol reduction of GO and RhCl 3 . • Complete HDC of 4-chlorophenol was obtained in aqueous phase without any additive. • The Rh/RGO exhibited an excellent catalytic performance for HDC reaction. - Abstract: Reduced graphene oxide (RGO) supported rhodium nanoparticles (Rh-NPs/RGO) was synthesized through one-pot polyol co-reduction of graphene oxide (GO) and rhodium chloride. The catalytic property of Rh-NPs/RGO was investigated for the aqueous phase hydrodechlorination (HDC) of 4-chlorophenol (4-CP). A complete conversion of 4-CP into high valued products of cyclohexanone (selectivity: 23.2%) and cyclohexanol (selectivity: 76.8%) was successfully achieved at 303 K and balloon hydrogen pressure in a short reaction time of 50 min when 1.5 g/L of 4-CP was introduced. By comparing with Rh-NPs deposited on the other supports, Rh-NPs/RGO delivered the highest initial rate (111.4 mmol/g Rh min) for 4-CP HDC reaction under the identical conditions. The substantial catalytic activity of Rh-NPs/RGO can be ascribed to the small and uniform particle size of Rh (average particle size was 1.7 ± 0.14 nm) on the surface of the RGO sheets and an electron-deficient state of Rh in the catalyst as a result of the strong interaction between the active sites and the surface function groups of RGO

  17. Chronic Mild Cold Conditioning Modulates the Expression of Hypothalamic Neuropeptide and Intermediary Metabolic-Related Genes and Improves Growth Performances in Young Chicks.

    Directory of Open Access Journals (Sweden)

    Phuong Nguyen

    Full Text Available Low environmental temperatures are among the most challenging stressors in poultry industries. Although landmark studies using acute severe cold exposure have been conducted, still the molecular mechanisms underlying cold-stress responses in birds are not completely defined. In the present study we determine the effect of chronic mild cold conditioning (CMCC on growth performances and on the expression of key metabolic-related genes in three metabolically important tissues: brain (main site for feed intake control, liver (main site for lipogenesis and muscle (main site for thermogenesis.80 one-day old male broiler chicks were divided into two weight-matched groups and maintained in two different temperature floor pen rooms (40 birds/room. The temperature of control room was 32°C, while the cold room temperature started at 26.7°C and gradually reduced every day (1°C/day to reach 19.7°C at the seventh day of the experiment. At day 7, growth performances were recorded (from all birds and blood samples and tissues were collected (n = 10. The rest of birds were maintained at the same standard environmental condition for two more weeks and growth performances were measured.Although feed intake remained unchanged, body weight gain was significantly increased in CMCC compared to the control chicks resulting in a significant low feed conversion ratio (FCR. Circulating cholesterol and creatine kinase levels were higher in CMCC chicks compared to the control group (P<0.05. CMCC significantly decreased the expression of both the hypothalamic orexigenic neuropeptide Y (NPY and anorexigenic cocaine and amphetamine regulated transcript (CART in chick brain which may explain the similar feed intake between the two groups. Compared to the control condition, CMCC increased the mRNA abundance of AMPKα1/α2 and decreased mTOR gene expression (P<0.05, the master energy and nutrient sensors, respectively. It also significantly decreased the expression of fatty

  18. Increased Cortical Gamma-Aminobutyric Acid Precedes Incomplete Extinction of Conditioned Fear and Increased Hippocampal Excitatory Tone in a Mouse Model of Mild Traumatic Brain Injury.

    Science.gov (United States)

    Schneider, Brandy L; Ghoddoussi, Farhad; Charlton, Jennifer L; Kohler, Robert J; Galloway, Matthew P; Perrine, Shane A; Conti, Alana C

    2016-09-01

    Mild traumatic brain injury (mTBI) contributes to development of affective disorders, including post-traumatic stress disorder (PTSD). Psychiatric symptoms typically emerge in a tardive fashion post-TBI, with negative effects on recovery. Patients with PTSD, as well as rodent models of PTSD, demonstrate structural and functional changes in brain regions mediating fear learning, including prefrontal cortex (PFC), amygdala (AMYG), and hippocampus (HC). These changes may reflect loss of top-down control by which PFC normally exhibits inhibitory influence over AMYG reactivity to fearful stimuli, with HC contribution. Considering the susceptibility of these regions to injury, we examined fear conditioning (FC) in the delayed post-injury period, using a mouse model of mTBI. Mice with mTBI displayed enhanced acquisition and delayed extinction of FC. Using proton magnetic resonance spectroscopy ex vivo, we examined PFC, AMYG, and HC levels of gamma-aminobutyric acid (GABA) and glutamate as surrogate measures of inhibitory and excitatory neurotransmission, respectively. Eight days post-injury, GABA was increased in PFC, with no significant changes in AMYG. In animals receiving FC and mTBI, glutamate trended toward an increase and the GABA/glutamate ratio decreased in ventral HC at 25 days post-injury, whereas GABA decreased and GABA/glutamate decreased in dorsal HC. These neurochemical changes are consistent with early TBI-induced PFC hypoactivation facilitating the fear learning circuit and exacerbating behavioral fear responses. The latent emergence of overall increased excitatory tone in the HC, despite distinct plasticity in dorsal and ventral HC fields, may be associated with disordered memory function, manifested as incomplete extinction and enhanced FC recall.

  19. Effect of core body temperature, time of day, and climate conditions on behavioral patterns of lactating dairy cows experiencing mild to moderate heat stress.

    Science.gov (United States)

    Allen, J D; Hall, L W; Collier, R J; Smith, J F

    2015-01-01

    Cattle show several responses to heat load, including spending more time standing. Little is known about what benefit this may provide for the animals. Data from 3 separate cooling management trials were analyzed to investigate the relationship between behavioral patterns in lactating dairy cows experiencing mild to moderate heat stress and their body temperature. Cows (n=157) were each fitted with a leg data logger that measured position and an intravaginal data logger that measures core body temperature (CBT). Ambient conditions were also collected. All data were standardized to 5-min intervals, and information was divided into several categories: when standing and lying bouts were initiated and the continuance of each bout (7,963 lying and 6,276 standing bouts). In one location, cows were continuously subjected to heat-stress levels according to temperature-humidity index (THI) range (THI≥72). The THI range for the other 2 locations was below and above a heat-stress threshold of 72 THI. Overall and regardless of period of day, cows stood up at greater CBT compared with continuing to stand or switching to a lying position. In contrast, cows lay down at lower CBT compared with continuing to lie or switching to a standing position, and lying bouts lasted longer when cows had lower CBT. Standing bouts also lasted longer when cattle had greater CBT, and they were less likely to lie down (less than 50% of lying bouts initiated) when their body temperature was over 38.8°C. Also, cow standing behavior was affected once THI reached 68. Increasing CBT decreased lying duration and increased standing duration. A CBT of 38.93°C marked a 50% likelihood a cow would be standing. This is the first physiological evidence that standing may help cool cows and provides insight into a communally observed behavioral response to heat. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  20. Long-term monitoring reveals cold-water corals in extreme conditions off the southeast US coast

    Science.gov (United States)

    Mienis, F.; Duineveld, G.; Davies, A. J.; Ross, S. W.; Lavaleye, M.; Van Weering, T.

    2011-12-01

    Cold-water corals are common on the SE slope of the US (SEUS) from Florida to Cape Hatteras between depths of 400-600 m. Near Cape Hatteras cold-water corals have formed mound structures that are up to 60 m high, which are mainly covered by living colonies of the coral species Lophelia pertusa. Past explorations of major reef sites of N Carolina using remote and manned submersibles have shown living Lophelia pertusa colonies on the current facing side of the mound structures and a high biodiversity of associated fauna, especially fish. The coral areas lie in the vicinity of the Gulf Stream characterized by strong currents transporting relatively warm water northwards along the SEUS slope. Thus far little is known about the environmental conditions inside the SEUS coral communities and particularly the effects of the nearby Gulf Stream. In December 2009 two autonomous benthic landers were deployed amidst Lophelia reefs off Cape Lookout (NC) for a period of 6 months to define oceanographic patterns that are relevant for the development and persistence of cold-water coral ecosystems. Landers recorded temperature, fluorescence, turbidity, and current speed and direction. Furthermore, a sediment trap was mounted on the landers that collected material at a 16-days interval. A first analysis of the lander data shows that instability of the Gulf Stream causes rapid rises in temperature, current speed and turbidity lasting for days to more than a week. Peak temperature and turbidity levels are the highest measured in coral habitats studied so far. We did not see clear cut effects of Gulf Stream instabilities on the near bed flux of phytodetritus as opposed to reports of meanders inducing upwelling and enhanced production in the photic zone. Data analyzed so far suggest that cwc habitats of Cape Lookout experience extreme and adverse conditions for prolonged periods. The findings of this study are compared with methodologically similar studies that have been conducted in

  1. Coordinated Hard Sphere Mixture (CHaSM): A fast approximate model for oxide and silicate melts at extreme conditions

    Science.gov (United States)

    Wolf, A. S.; Asimow, P. D.; Stevenson, D. J.

    2015-12-01

    Recent first-principles calculations (e.g. Stixrude, 2009; de Koker, 2013), shock-wave experiments (Mosenfelder, 2009), and diamond-anvil cell investigations (Sanloup, 2013) indicate that silicate melts undergo complex structural evolution at high pressure. The observed increase in cation-coordination (e.g. Karki, 2006; 2007) induces higher compressibilities and lower adiabatic thermal gradients in melts as compared with their solid counterparts. These properties are crucial for understanding the evolution of impact-generated magma oceans, which are dominated by the poorly understood behavior of silicates at mantle pressures and temperatures (e.g. Stixrude et al. 2009). Probing these conditions is difficult for both theory and experiment, especially given the large compositional space (MgO-SiO2-FeO-Al2O3-etc). We develop a new model to understand and predict the behavior of oxide and silicate melts at extreme P-T conditions (Wolf et al., 2015). The Coordinated Hard Sphere Mixture (CHaSM) extends the Hard Sphere mixture model, accounting for the range of coordination states for each cation in the liquid. Using approximate analytic expressions for the hard sphere model, this fast statistical method compliments classical and first-principles methods, providing accurate thermodynamic and structural property predictions for melts. This framework is applied to the MgO system, where model parameters are trained on a collection of crystal polymorphs, producing realistic predictions of coordination evolution and the equation of state of MgO melt over a wide P-T range. Typical Mg-coordination numbers are predicted to evolve continuously from 5.25 (0 GPa) to 8.5 (250 GPa), comparing favorably with first-principles Molecular Dynamics (MD) simulations. We begin extending the model to a simplified mantle chemistry using empirical potentials (generally accurate over moderate pressure ranges, consuming classical MD calculations. This approach also sheds light on the universality

  2. Expert consensus on facilitators and barriers to return-to-work following surgery for non-traumatic upper extremity conditions : A Delphi study

    NARCIS (Netherlands)

    Peters, S. E.; Johnston, V.; Ross, M.; Coppieters, M. W.

    2017-01-01

    This Delphi study aimed to reach consensus on important facilitators and barriers for return-to-work following surgery for non-traumatic upper extremity conditions. In Round 1, experts (n = 42) listed 134 factors, which were appraised in Rounds 2 and 3. Consensus (3/485% agreement) was achieved for

  3. Unique Nature of the Quality of Life in the Context of Extreme Climatic, Geographical and Specific Socio-Cultural Living Conditions

    Science.gov (United States)

    Kulik, Anastasia; Neyaskina, Yuliya; Frizen, Marina; Shiryaeva, Olga; Surikova, Yana

    2016-01-01

    This article presents the results of a detailed empirical research, aimed at studying the quality of life in the context of extreme climatic, geographical and specific sociocultural living conditions. Our research is based on the methodological approach including social, economical, ecological and psychological characteristics and reflecting…

  4. Left–right coordination from simple to extreme conditions during split‐belt locomotion in the chronic spinal adult cat

    Science.gov (United States)

    Desrochers, Étienne; Thibaudier, Yann; Hurteau, Marie‐France; Dambreville, Charline

    2016-01-01

    Key points Coordination between the left and right sides is essential for dynamic stability during locomotion.The immature or neonatal mammalian spinal cord can adjust to differences in speed between the left and right sides during split‐belt locomotion by taking more steps on the fast side.We show that the adult mammalian spinal cord can also adjust its output so that the fast side can take more steps.During split‐belt locomotion, only certain parts of the cycle are modified to adjust left–right coordination, primarily those associated with swing onset.When the fast limb takes more steps than the slow limb, strong left–right interactions persist.Therefore, the adult mammalian spinal cord has a remarkable adaptive capacity for left–right coordination, from simple to extreme conditions. Abstract Although left–right coordination is essential for locomotion, its control is poorly understood, particularly in adult mammals. To investigate the spinal control of left–right coordination, a spinal transection was performed in six adult cats that were then trained to recover hindlimb locomotion. Spinal cats performed tied‐belt locomotion from 0.1 to 1.0 m s−1 and split‐belt locomotion with low to high (1:1.25–10) slow/fast speed ratios. With the left hindlimb stepping at 0.1 m s−1 and the right hindlimb stepping from 0.2 to 1.0 m s−1, 1:1, 1:2, 1:3, 1:4 and 1:5 left–right step relationships could appear. The appearance of 1:2+ relationships was not linearly dependent on the difference in speed between the slow and fast belts. The last step taken by the fast hindlimb displayed longer cycle, stance and swing durations and increased extensor activity, as the slow limb transitioned to swing. During split‐belt locomotion with 1:1, 1:2 and 1:3 relationships, the timing of stance onset of the fast limb relative to the slow limb and placement of both limbs at contact were invariant with increasing slow/fast speed ratios. In contrast, the timing of

  5. Assessing the importance of spatio-temporal RCM resolution when estimating sub-daily extreme precipitation under current and future climate conditions

    DEFF Research Database (Denmark)

    Sunyer Pinya, Maria Antonia; Luchner, J.; Onof, C.

    2017-01-01

    extreme precipitation over Denmark generated by the regional climate model (RCM) HIRHAM-ECEARTH at different spatial resolutions (8, 12, 25 and 50km), three RCM from the RiskChange project at 8km resolution and three RCMs from ENSEMBLES at 25km resolution at temporal aggregations from 1 to 48h...... are more skewed than the observational dataset, which leads to an overestimation by the higher spatial resolution simulations. Nevertheless, in general, under current conditions RCM simulations at high spatial resolution represent extreme events and high-order moments better. The changes projected...

  6. Identification of Extreme Events Under Climate Change Conditions Over Europe and The Northwest-atlantic Region: Spatial Patterns and Time Series Characteristics

    Science.gov (United States)

    Leckebusch, G.; Ulbrich, U.; Speth, P.

    In the context of climate change and the resulting possible impacts on socio-economic conditions for human activities it seems that due to a changed occurrence of extreme events more severe consequences have to be expected than from changes in the mean climate. These extreme events like floods, excessive heats and droughts or windstorms possess impacts on human social and economic life in different categories such as forestry, agriculture, energy use, tourism and the reinsurance business. Reinsurances are affected by nearly 70% of all insured damages over Europe in the case of wind- storms. Especially the December 1999 French windstorms caused damages about 10 billion. A new EU-founded project (MICE = Modelling the Impact of Climate Ex- tremes) will focus on these impacts caused by changed occurrences of extreme events over Europe. Based upon the output of general circulation models as well as regional climate models, investigations are carried out with regard to time series characteristics as well as the spatial patterns of extremes under climate changed conditions. After the definition of specific thresholds for climate extremes, in this talk we will focus on the results of the analysis for the different data sets (HadCM3 and CGCMII GCM's and RCM's, re-analyses, observations) with regard to windstorm events. At first the results of model outputs are validated against re-analyses and observations. Especially a comparison of the stormtrack (2.5 to 8 day bandpass filtered 500 hPa geopotential height), cyclone track, cyclone frequency and intensity is presented. Highly relevant to damages is the extreme wind near the ground level, so the 10 m wind speed will be investigated additionally. of special interest to possible impacts is the changed spatial occurrence of windspeed maxima under 2xCO2-induced climate change.

  7. EXTREME WINTERS IN XX–XXI CENTURIES AS INDICATORS OF SNOWINESS AND AVALANCHE HAZARD IN THE PAST AND EXPECTED CLIMATE CHANGE CONDITIONS

    Directory of Open Access Journals (Sweden)

    A. D. Oleynikov

    2012-01-01

    Full Text Available Currently, due to the global climate change and increasing frequency of weather events focus is on prediction of climate extremes. Large-scale meteorological anomalies can cause long-term paralysis of social and economic infrastructure of the major mountain regions and even individual states. In winter periods, these anomalies are associated with prolonged heavy snowfalls and associated with them catastrophic avalanches which cause significant social and economic damage. The climate system maintains a certain momentum during periods of adjustment and transition to other conditions in the ratio of heat and moisture and contains a climate «signal» of the climates of the past and the future. In our view seasonal and yearly extremes perform the role of these indicators, study of which enables for a deeper understanding and appreciation of the real situation of the climate periods related to the modern ones. The paper provides an overview of the criteria for selection of extreme winters. Identification of extremely cold winters during the period of instrumental observation and assessment of their snowiness and avalanche activity done for the Elbrus region, which is a model site for study of the avalanche regime in the Central Caucasus. The studies aim to identify the extreme winters in the Greater Caucasus, assess their frequency of occurrence, characterize the scale and intensity of the avalanche formation. The data obtained can be used to identify winter-analogues in the reconstruction and long-term forecast of avalanches. 

  8. A joint analysis of wave and surge conditions for past and present extrem events in the south-western Baltic Sea

    Science.gov (United States)

    Groll, Nikolaus; Gaslikova, Lidia

    2017-04-01

    Extreme marine events in the south-western Baltic Sea like the historic storm in 1872 are rare, but have large impacts on human safety and coastal infrastructure. The aforementioned extreme storm event of 1872 and has cost over 250 human lives, left severely damaged infrastructure and caused land loss due to coastal erosion. Recent extreme events also result in drastic impacts to coastal regions. Using results from numerical wave and hydrodynamic model simulations we will present a joint analysis of wave and water level conditions for selected extreme events. For the historic event the numerical models have been forced by reconstructed wind and pressure fields from pressure readings. Simulated atmospheric conditions from reanalysis have been used for the more recent events. The height of the water level due to the possible previous inflow of water masses in the Baltic Sea basin, as well as possible seiches and swell effects have been incorporated in the simulations. We will discuss similarities and differences between the historic and the more recent marine hazard events.

  9. Temporal variation of sandy beach macrofauna at two sites with distinct environmental conditions on Cassino Beach, extreme southern Brazil

    Directory of Open Access Journals (Sweden)

    Pedro de Sá Rodrigues da Silva

    2008-12-01

    Full Text Available Temporal variations of the macrofauna of sandy beaches have been related to variations in the beach morphodynamics and also to the population dynamics of dominant species. The aim of this article is to describe the temporal variation of the intertidal macrofauna at two sites with distinct environmental condition on Cassino Beach, extreme southern Brazil. At each site three transect lines 50 m apart were defined perpendicular to the shore line, from which samples were collected monthly in triplicate at 4 intertidal levels (10 m apart from June 2004 to May 2005. During winter a generally low density was observed, due to the absence of recruitments and to the mud deposition, which occurred just before sampling (in April 2004, and to low intensity stranding events. Spring witnessed a population explosion of Scolelepis gaucha, a migration of Mesodesma mactroides adults from the subtidal zone, and a strong stranding event. In the summer, recruitment of M. mactroides, Donax hanleyanus and Emerita brasiliensis was observed. Fall was characterized by low densities, except for D. hanleyanus recruitment. The macrofauna at both sites showed a striking seasonal variation in density and diversity, perhaps attributable to the recruitment of numerically dominant species and physical disturbances (stranding and mud deposition.Variações sazonais da macrofauna bentônica de praias arenosas têm sido relacionadas com variações da morfodinâmica da praia e também aos recrutamentos das espécies dominantes. Este trabalho objetiva avaliar a variabilidade temporal da macrofauna da zona entremarés de dois locais com distintas características ambientais na praia do Cassino, extremo sul do Brasil. Em cada local foram demarcadas três transversais (separadas por 50m perpendiculares à linha de água, nas quais amostras foram coletadas em triplicata em 4 níveis entremarés (separados por 10 m, entre junho/2004 e maio/2005. Durante o inverno ocorreram baixas

  10. Considerations concerning the physics of nuclear matter under extreme conditions and an accelerator for relativistic heavy ions

    International Nuclear Information System (INIS)

    Blasche, K.; Bock, R.; Franzke, B.; Greiner, W.; Gutbrod, H.H.; Povh, B.; Schmelzer, C.; Stock, R.

    1977-01-01

    The future problems of heavy-ion physics in the 10 GeV/U range are dealt with: the dynamics of relativistic nuclear collisions, phase transitions, nuclear matter, quantum electrodynamics of extremely strong fields, and astrophysical aspects. In the second part, the project of a heavy-ion accelerator in the 10 GeV/U range to be coupled to the present GSI UNILAC accelerator is discussed. (WL) [de

  11. Observations and predictions of wave runup, extreme water levels, and medium-term dune erosion during storm conditions

    OpenAIRE

    Suanez , Serge ,; Cancouët , Romain; Floc'h , France; Blaise , Emmanuel; Ardhuin , Fabrice; Filipot , Jean-François; Cariolet , Jean-Marie; Delacourt , Christophe

    2015-01-01

    Monitoring of dune erosion and accretion on the high-energy macrotidal Vougot beach in North Brittany (France) over the past decade (2004–2014) has revealed significant morphological changes. Dune toe erosion/accretion records have been compared with extreme water level measurements, defined as the sum of (i) astronomic tide; (ii) storm surge; and (iii) vertical wave runup. Runup parameterization was conducted using swash limits, beach profiles, and hydrodynamic (Hm0, Tm0,–1, and high tide wa...

  12. Coupled large-eddy simulation and morphodynamics of a large-scale river under extreme flood conditions

    Science.gov (United States)

    Khosronejad, Ali; Sotiropoulos, Fotis; Stony Brook University Team

    2016-11-01

    We present a coupled flow and morphodynamic simulations of extreme flooding in 3 km long and 300 m wide reach of the Mississippi River in Minnesota, which includes three islands and hydraulic structures. We employ the large-eddy simulation (LES) and bed-morphodynamic modules of the VFS-Geophysics model to investigate the flow and bed evolution of the river during a 500 year flood. The coupling of the two modules is carried out via a fluid-structure interaction approach using a nested domain approach to enhance the resolution of bridge scour predictions. The geometrical data of the river, islands and structures are obtained from LiDAR, sub-aqueous sonar and in-situ surveying to construct a digital map of the river bathymetry. Our simulation results for the bed evolution of the river reveal complex sediment dynamics near the hydraulic structures. The numerically captured scour depth near some of the structures reach a maximum of about 10 m. The data-driven simulation strategy we present in this work exemplifies a practical simulation-based-engineering-approach to investigate the resilience of infrastructures to extreme flood events in intricate field-scale riverine systems. This work was funded by a Grant from Minnesota Dept. of Transportation.

  13. A generalized sine condition and performance comparison of Wolter type II and Wolter-Schwarzschild extreme ultraviolet telescopes

    Science.gov (United States)

    Saha, T. T.

    1984-01-01

    An equation similar to the Abbe sine condition is derived for a Wolter type II telescope. This equation and the sine condition are then combined to produce a so called generalized sine condition. Using the law of reflection, Fermat's principle, the generalized sine condition, and simple geometry the surface equations for a Wolter type II telescope and an equivalent Wolter-Schwarzschild telescope are calculated. The performances of the telescopes are compared in terms of rms blur circle radius at the Gaussian focal plane and at best focus.

  14. Sensitivities of crop models to extreme weather conditions during flowering period demonstrated for maize and winter wheat in Austria

    DEFF Research Database (Denmark)

    Eitzinger, J; Thaler, S; Schmid, E

    2013-01-01

    the start of flowering. Two locations in Austria, representing different agro-climatic zones and soil conditions, were included in the simulations over 2 years, 2003 and 2004, exhibiting contrasting weather conditions. In addition, soil management was modified at both sites by following either ploughing...

  15. Decrease in hydroclimatic conditions generating floods in the southeast of Belgium over the last 50 years resulting from changes in seasonal snow cover and extreme precipitation events

    Science.gov (United States)

    Wyard, Coraline; Fettweis, Xavier

    2016-04-01

    As a consequence of climate change, several studies concluded that winter flood occurrence could increase in the future in many rivers of northern and western Europe in response to an increase in extreme precipitation events. This study aims to determine if trends in extreme hydroclimatic events generating floods can already be detected over the last century. In particular, we focus on the Ourthe River (southeast of Belgium) which is one of the main tributaries of the Meuse River with a catchment area of 3500 km². In this river, most of the floods occur during winter and about 50% of them are due to rainfall events associated with the melting of the snow which covers the Ardennes during winter. In this study, hydroclimatic conditions favorable to flooding were reconstructed over the 20th century using the regional climate model MAR ("Modèle Atmosphérique Régional") forced by the following reanalyses: the ERA-20C, the ERA-Interim and the NCEP/NCAR-v1. The use of the MAR model allows to compute precipitation, snow depth and run-off resulting from precipitation events and snow melting in any part of the Ourthe river catchment area. Therefore, extreme hydroclimatic events, namely extreme run-off events, which could potentially generate floods, can be reconstructed using the MAR model. As validation, the MAR results were compared to weather station-based data. A trend analysis was then performed in order to study the evolution of conditions favorable to flooding in the Ourthe River catchment. The results show that the MAR model allows the detection of more than 95% of the hydroclimatic conditions which effectively generated observed floods in the Ourthe River over the 1974-2014 period. Conditions favorable to flooding present a negative trend over the last 50 years as a result of a decrease in snow accumulation and in extreme precipitation events. However, significance of these trends depends on the reanalysis used to force the regional climate model as well as the

  16. The near-term prediction of drought and flooding conditions in the northeastern United States based on extreme phases of AMO and NAO

    Science.gov (United States)

    Berton, Rouzbeh; Driscoll, Charles T.; Adamowski, Jan F.

    2017-10-01

    frequency of wet, average, and dry discharge conditions with regards to the extreme phases of AMO and NAO. While the function was decaying, the tail asymptotically merged into and stabilized at the theoretical probability of the event. As the basin scale increased, the probability of wet, average, and dry discharge conditions decreased. The Merrimack River watershed will most likely experience greater than average discharge as its extreme condition, therefore development should be avoided on flood plains. Furthermore, the current reservoir storage capacity in the Merrimack should be improved in order to accommodate excess water input and minimize flood damage. Future research should target changes in the magnitude and timing of high discharge events in order to develop adaptation strategies for aging hydraulic infrastructure in the region.

  17. Mild Cognitive Impairment (MCI)

    Science.gov (United States)

    Mild cognitive impairment (MCI) Overview Mild cognitive impairment (MCI) is an intermediate stage between the expected cognitive decline of normal aging and the more-serious decline of dementia. It ...

  18. Precipitation of Oriented Rutile and Ilmenite Needles in Garnet, Northeastern Connecticut, USA: Evidence for Extreme Metamorphic Conditions?

    Science.gov (United States)

    Ague, J. J.; Eckert, J. O.

    2011-12-01

    We report the discovery of oriented needles of rutile and, less commonly, ilmenite in the cores of garnets from northeastern CT, USA. The rocks preserve granulite facies mineral assemblages, form part of the Merrimack Synclinorium, and underwent metamorphism and deformation during the Acadian orogeny. The needles appear identical to those reported from a number of extreme P-T environments worldwide, including UHP metamorphic rocks, high-P granulites, and garnet peridotites. The needles are predominantly oriented along directions in garnet. The long axes of the rutile needles commonly do not go extinct parallel to the cross hairs under cross-polarized light (e.g., Griffin et al., 1971). This anomalous extinction indicates that the needles do not preserve a specific crystallographic relationship with their garnet hosts (e.g., Hwang et al., 2007). The needles range from a few hundred nm to a few um in diameter, and can be mm-scale in length. Micrometer-scale plates of rutile, srilankite and crichtonite have also been observed in some garnets together with the Fe-Ti oxide needles. Several origins for the needles have been proposed in the literature; we investigate the hypothesis that they precipitated in situ from originally Ti-rich garnet. Chemical profiles across garnets indicate that some retain Ti zoning, with elevated-Ti concentrations in the cores dropping to low values in the rims. For these zoned garnets, high-resolution, 2-D chemical mapping using the JEOL JXA-8530F field emission gun electron microprobe at Yale University reveals that the needles are surrounded by well-defined Ti-depletion halos. Chemical profiles also document strong depletions of Cr (which is present in both rutile and ilmenite) directly adjacent to needles. The observed Ti-depletions demonstrate that the needles precipitated from Ti-bearing garnet, probably during cooling and/or decompression associated with exhumation. The rutile precipitates must be largely incoherent with respect to the

  19. Development of a high-resolution apparatus to monitor physiological state of a person undergoing extreme conditions

    Directory of Open Access Journals (Sweden)

    Kodermyatov Radik

    2016-01-01

    Full Text Available The present research has shown that ECG recordings and parameters of the body functional state are crucial for all kinds of the astronaut pre-flight preparations (centrifuge, thermal chamber, pressure chamber, pressure chamber with special equipment. It is, therefore, important to develop methods and tools for early detection of the preclinical forms of the functional state disorders in patients undergoing high-intensity loads of mixed character. The method based on the hardware-software compleх (HSC with nanosensors of high resolution has been proposed to measure the electrophysiological characteristics and bioelectrical impedance of the body tissues directly exposed to loading. The hardware-software compleх is subjected to clinical trials in Tomsk Research Institute for Cardiology. The obtained results show that the use of nanosensors of high resolution in the HSC without standard filters allows elimination of the power-line interference in ECG recordings. Monitoring of the tissue bioimpedance parameters under test loads enables the detection of preclinical (latent forms of various diseases. After clinical trials in Tomsk Institute for Cardiology the developed apparatus will be proposed for in-depth study of the cardiovascular system and the functional state of the body of astronauts and other persons exposed to extreme loads.

  20. Potential changes in the extreme climate conditions at the regional scale: from observed data to modelling approaches and towards probabilistic climate change information

    International Nuclear Information System (INIS)

    Gachon, P.; Radojevic, M.; Harding, A.; Saad, C.; Nguyen, V.T.V.

    2008-01-01

    The changes in the characteristics of extreme climate conditions are one of the most critical challenges for all ecosystems, human being and infrastructure, in the context of the on-going global climate change. However, extremes information needed for impacts studies cannot be obtained directly from coarse scale global climate models (GCMs), due mainly to their difficulties to incorporate regional scale feedbacks and processes responsible in part for the occurrence, intensity and duration of extreme events. Downscaling approaches, namely statistical and dynamical downscaling techniques (i.e. SD and RCM), have emerged as useful tools to develop high resolution climate change information, in particular for extremes, as those are theoretically more capable to take into account regional/local forcings and their feedbacks from large scale influences as they are driven with GCM synoptic variables. Nevertheless, in spite of the potential added values from downscaling methods (statistical and dynamical), a rigorous assessment of these methods are needed as inherent difficulties to simulate extremes are still present. In this paper, different series of RCM and SD simulations using three different GCMs are presented and evaluated with respect to observed values over the current period and over a river basin in southern Quebec, with future ensemble runs, i.e. centered over 2050s (i.e. 2041-2070 period using the SRES A2 emission scenario). Results suggest that the downscaling performance over the baseline period significantly varies between the two downscaling techniques and over various seasons with more regular reliable simulated values with SD technique for temperature than for RCM runs, while both approaches produced quite similar temperature changes in the future from median values with more divergence for extremes. For precipitation, less accurate information is obtained compared to observed data, and with more differences among models with higher uncertainties in the

  1. Sensitivities of crop models to extreme weather conditions during flowering period demonstrated for maize and winter wheat in Austria

    Czech Academy of Sciences Publication Activity Database

    Eitzinger, Josef; Thaler, S.; Schmid, E.; Strauss, F.; Ferrise, R.; Moriondo, M.; Bindi, M.; Palosuo, T.; Rötter, R.; Kersebaum, K. C.; Olesen, J. E.; Patil, R. H.; Saylan, L.; Çaldag, B.; Caylak, O.

    2013-01-01

    Roč. 151, č. 6 (2013), s. 813-835 ISSN 0021-8596 R&D Projects: GA MŠk(CZ) ED1.1.00/02.0073 Institutional support: RVO:67179843 Keywords : crop models * weather conditions * winter wheat * Austria Subject RIV: EH - Ecology, Behaviour Impact factor: 2.891, year: 2013

  2. Adaptive Coping under Conditions of Extreme Stress: Multilevel Influences on the Determinants of Resilience in Maltreated Children

    Science.gov (United States)

    Cicchetti, Dante; Rogosch, Fred A.

    2009-01-01

    The study of resilience in maltreated children reveals the possibility of coping processes and resources on multiple levels of analysis as children strive to adapt under conditions of severe stress. In a maltreating context, aspects of self-organization, including self-esteem, self-reliance, emotion regulation, and adaptable yet reserved…

  3. Monitoring of prestressed concrete pressure vessels. II. performance of selected concrete embedment strain meters under normal and extreme environmental conditions

    International Nuclear Information System (INIS)

    Naus, D.J.; Hurtt, C.C.

    1978-10-01

    Unique types of instrumentation are used in prestressed concrete pressure vessels (PCPVs) to measure strains, stresses, deflections, prestressing forces, moisture content, temperatures, and possibly cracking. Their primary purpose is to monitor these complex structures throughout their 20- to 30-year operating lifetime in order to provide continuing assurance of their reliability and safety. Numerous concrete embedment instrumentation systems are available commercially. Since this instrumentation is important in providing continuing assurance of satisfactory performance of PCPVs, the information provided must be reliable. Therefore, laboratory studies were conducted to evaluate the reliability of these commercially available instrumentation systems. This report, the second in a series related to instrumentation embedded in concrete, presents performance-reliability data for 13 types of selected concrete embedment strain meters which were subjected to a variety of loading environments, including unloaded, thermally loaded, simulated PCPV, and extreme environments. Although only a limited number of meters of each type were tested in any one test series, the composite results of the investigation indicate that the majority of these meters would not be able to provide reliable data throughout the 20- to 30-year anticipated operating life of a PCPV. Specific conclusions drawn from the study are: (1) Improved corrosion-resistant materials and sealing techniques should be developed for meters that are to be used in PCPV environments. (2) There is a need for the development of meters that are capable of surviving in concretes where temperatures in excess of 66 0 C are present for extended periods of time. (3) Research should be conducted on other measurement techniques, such as inductance, capacitance, and fluidics

  4. Extreme late chronotypes and social jetlag challenged by Antarctic conditions in a population of university students from Uruguay.

    Science.gov (United States)

    Tassino, Bettina; Horta, Stefany; Santana, Noelia; Levandovski, Rosa; Silva, Ana

    2016-01-01

    In humans, a person's chronotype depends on environmental cues and on individual characteristics, with late chronotypes prevailing in youth. Social jetlag (SJL), the misalignment between an individual׳s biological clock and social time, is higher in late chronotypes. Strong SJL is expected in Uruguayan university students with morning class schedules and very late entertainment activities. Sleep disorders have been reported in Antarctic inhabitants, that might be a response to the extreme environment or to the strictness of Antarctic life. We evaluated, for the first time in Uruguay, the chronotypes and SJL of 17 undergraduate students of the First Uruguayan Summer School on Antarctic Research, using Munich Chronotype Questionnaire (MCTQ) and sleep logs (SL) recorded during 3 phases: pre-Antarctic, Antarctic, and post-Antarctic. The midsleep point of free days corrected for sleep debt on work days (MSFsc,) was used as proxy of individuals' chronotype, whose values (around 6 a.m.) are the latest ever reported. We found a SJL of around 2 h in average, which correlated positively with MSFsc, confirming that late chronotypes generate a higher sleep debt during weekdays. Midsleep point and sleep duration significantly decreased between pre-Antarctic and Antarctic phases, and sleep duration rebounded to significant higher values in the post-Antarctic phase. Waking time, but not sleep onset time, significantly varied among phases. This evidence suggests that sleep schedules more likely depended on the social agenda than on the environmental light-dark shifts. High motivation of students towards Antarctic activities likely induced a subjective perception of welfare non-dependent on sleep duration.

  5. A comparison of spent fuel shipping cask response to 10 CFR 71 normal conditions and realistic hot day extremes

    International Nuclear Information System (INIS)

    Manson, S.J.; Gianoulakis, S.E.

    1994-04-01

    An examination of the effect of a realistic (though conservative) hot day environment on the thermal transient behavior of spent fuel shipping casks is made. These results are compared to those that develop under the prescribed normal thermal condition of 10 CFR 71. Of specific concern are the characteristics of propagating thermal waves, which are set up by diurnal variations of temperature and insolation in the outdoor environment. In order to arrive at a realistic approximation of these variations on a conservative hot day, actual temperature and insolation measurements have been obtained from the National Climatic Data Center (NCDC) for representatively hot and high heat flux days. Thus, the use of authentic meteorological data ensures the realistic approach sought. Further supporting the desired realism of the modeling effort is the use of realistic cask configurations in which multiple laminations of structural, shielding, and other materials are expected to attenuate the propagating thermal waves. The completed analysis revealed that the majority of wall temperatures, for a wide variety of spent fuel shipping cask configurations, fall well below those predicted by enforcement of the regulatory environmental conditions of 10 CFR 71. It was found that maximum temperatures at the cask surface occasionally lie above temperatures predicted under the prescribed regulatory conditions. However, the temperature differences are small enough that the normal conservative assumptions that are made in the course of typical cask evaluations should correct for any potential violations. The analysis demonstrates that diurnal temperature variations that penetrate the cask wall all have maxima substantially less than the corresponding regulatory solutions. Therefore it is certain that vital cask components and the spent fuel itself will not exceed the temperatures calculated by use of the conditions of 10 CFR 71

  6. Development of manganese toxicity in pasture legumes under extreme climatic conditions. [Trifolium subterraneum; Medicago sativa; Brassica campestris

    Energy Technology Data Exchange (ETDEWEB)

    Siman, A; Cradock, F W; Hudson, A W

    1974-08-01

    Manganese levels and pH in soil were measured on limed and unlimed plots at bi-monthly intervals for two years at five field sites with lucerne (Medicago sativa) and subterranean clover (Trifolium subterraneum) and related to rainfall and temperature. Pot experiments with lucerne, subterranean clover and rape (Brassica campestris) were used to confirm the results of the field experiments. Manganese toxicity developed in lucerne and subterranean clover under waterlogged conditions after heavy rain on the slightly acid soils (pH 4.7-5.5). Lucerne also showed manganese toxicity on the same soils in summer after extended hot, dry conditions. The maximum available manganese was 210 ..mu..g/g in the waterlogged soil (0-15 cm) the 128 ..mu..g/g in the heat affected soil. Lime treatment of 2240 kg/ha reduced the maximum available manganese to 148 ..mu..g/g in waterlogged plots and to 47 ..mu..g/g in the heat affected plots but failed to correct manganese toxicity. However, lime corrected toxicity symptoms under less severe conditions. In the pot experiments, available manganese reached 270 ..mu..g/g after 2 weeks artificial waterlogging and 68 ..mu..g/g after 2 weeks dry heat exposure. 12 references, 4 figures, 3 tables.

  7. Stability of fluorite-type La{sub 2}Ce{sub 2}O{sub 7} under extreme conditions

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, F.X., E-mail: zhangfx@umich.edu [Department of Earth and Environmental Sciences, The University of Michigan, Ann Arbor, MI 48109 (United States); State Key Laboratory of Metastable Materials Science & Technology, Yanshan University, Qinhuangdao, Hebei 066004 (China); Tracy, C.L. [Department of Materials Science and Engineering, The University of Michigan, Ann Arbor, MI 48109 (United States); Lang, M. [Department of Nuclear Engineering, University of Tennessee, Knoxville, TN 37966 (United States); Ewing, R.C. [Department of Geological Sciences, Stanford University, Stanford, CA 94305 (United States)

    2016-07-25

    The structural stability of fluorite-type La{sub 2}Ce{sub 2}O{sub 7} was studied at pressure up to ∼40 GPa and under hydrothermal conditions of ∼1 GPa and up to 350 °C, respectively, using synchrotron X-ray diffraction (XRD) and Raman scattering measurements. XRD measurements indicated that the fluorite-type La{sub 2}Ce{sub 2}O{sub 7} is not stable at pressures greater than 22.6 GPa and gradually transformed to a high-pressure phase. The high-pressure phase is not stable and changed back to the fluorite-type structure when pressure is released. The La{sub 2}Ce{sub 2}O{sub 7} fluorite is also not stable under hydrothermal conditions and began to react with water at 200–250 °C. Both Raman and XRD results suggest that lanthanum hydroxide La(OH){sub 3} and La{sup 3+}-doped CeO{sub 2} fluorite are the dominant products after hydrothermal treatment. - Graphical abstract: The fluorite-type La{sub 2}Ce{sub 2}O{sub 7} reacted with water at hydrothermal condition (1 GPa, and above 200 °C), and formed rare earth hydroxides. - Highlights: • La{sub 2}Ce{sub 2}O{sub 7} transforms to a metastable phase at pressure higher than 21 GPa. • La{sub 2}Ce{sub 2}O{sub 7} reacts with water at ∼1 GPa and above 200 °C. • The pressure-induced phase transition is reversible.

  8. Improving real-time estimation of heavy-to-extreme precipitation using rain gauge data via conditional bias-penalized optimal estimation

    Science.gov (United States)

    Seo, Dong-Jun; Siddique, Ridwan; Zhang, Yu; Kim, Dongsoo

    2014-11-01

    A new technique for gauge-only precipitation analysis for improved estimation of heavy-to-extreme precipitation is described and evaluated. The technique is based on a novel extension of classical optimal linear estimation theory in which, in addition to error variance, Type-II conditional bias (CB) is explicitly minimized. When cast in the form of well-known kriging, the methodology yields a new kriging estimator, referred to as CB-penalized kriging (CBPK). CBPK, however, tends to yield negative estimates in areas of no or light precipitation. To address this, an extension of CBPK, referred to herein as extended conditional bias penalized kriging (ECBPK), has been developed which combines the CBPK estimate with a trivial estimate of zero precipitation. To evaluate ECBPK, we carried out real-world and synthetic experiments in which ECBPK and the gauge-only precipitation analysis procedure used in the NWS's Multisensor Precipitation Estimator (MPE) were compared for estimation of point precipitation and mean areal precipitation (MAP), respectively. The results indicate that ECBPK improves hourly gauge-only estimation of heavy-to-extreme precipitation significantly. The improvement is particularly large for estimation of MAP for a range of combinations of basin size and rain gauge network density. This paper describes the technique, summarizes the results and shares ideas for future research.

  9. Assessment of extreme hydrological conditions in the Bothnian Bay, Baltic Sea, and the impact of the nuclear power plant "Hanhikivi-1" on the local thermal regime

    Science.gov (United States)

    Dvornikov, Anton Y.; Martyanov, Stanislav D.; Ryabchenko, Vladimir A.; Eremina, Tatjana R.; Isaev, Alexey V.; Sein, Dmitry V.

    2017-04-01

    The results of the study aimed to assess the influence of future nuclear power plant Hanhikivi-1 upon the local thermal conditions in the Bothnian Bay in the Baltic Sea are presented. A number of experiments with different numerical models were also carried out in order to estimate the extreme hydro-meteorological conditions in the area of the construction. The numerical experiments were fulfilled both with analytically specified external forcing and with real external forcing for 2 years: a cold year (2010) and a warm year (2014). The study has shown that the extreme values of sea level and water temperature and the characteristics of wind waves and sea ice in the vicinity of the future nuclear power plant can be significant and sometimes catastrophic. Permanent release of heat into the marine environment from an operating nuclear power plant will lead to a strong increase in temperature and the disappearance of ice cover within a 2 km vicinity of the station. These effects should be taken into account when assessing local climate changes in the future.

  10. Dynamics of indicators of a metabolic exchange and condition of blood circulation of the bottom extremities after traction extension at patients with lumbar and sacral dorsopathy

    Directory of Open Access Journals (Sweden)

    Kotenko К.V.

    2013-12-01

    Full Text Available Aim: to study influence of traction therapy in a pulse mode in a complex with electrotherapy on a condition of blood circulation of the bottom extremities and level of a metabolic exchange. Material and methods. There had been examined 120 patients with a lumbar and sacral dorsopathy aged from 22 to 69 years (middle age of 49,5 years with prescription of a disease from 1 to 5 years, among them men of 34,2%, women of 65,8%. Results. The analysis of effects of various medical methods on a condition of local blood circulation in the bottom extremities showed that the most expressed its compensation is noted at complex application of mechanical pulse traction influence and electrotherapy for patients with a dorsopathy of lumbar and sacral department of a backbone that is confirmed by restoration to normal values of all indicators rheovasogramm. Conclusion. High clinical results of application of the combined medical and rehabilitation complex are based on compensation of local blood circulation that is shown in elimination of deficiency of blood supply due to improvement of a tone of arterial vessels and elimination of venous stagnation, and also due to increase of linear speed of a blood-groove and development of collateral blood circulation. Application of electrical impulse and mechanical traction influences, more at their combination promotes fermentative activity of the systems responsible for a protein exchange that is important for prevention of degenerate and dystrophic process progressing.

  11. Consortium for Health and Military Performance and American College of Sports Medicine consensus paper on extreme conditioning programs in military personnel.

    Science.gov (United States)

    Bergeron, Michael F; Nindl, Bradley C; Deuster, Patricia A; Baumgartner, Neal; Kane, Shawn F; Kraemer, William J; Sexauer, Lisa R; Thompson, Walter R; O'Connor, Francis G

    2011-01-01

    A potential emerging problem associated with increasingly popularized extreme conditioning programs (ECPs) has been identified by the military and civilian communities. That is, there is an apparent disproportionate musculoskeletal injury risk from these demanding programs, particularly for novice participants, resulting in lost duty time, medical treatment, and extensive rehabilitation. This is a significant and costly concern for the military with regard to effectively maintaining operational readiness of the Force. While there are certain recognized positive aspects of ECPs that address a perceived and/or actual unfulfilled conditioning need for many individuals and military units, these programs have limitations and should be considered carefully. Moreover, certain distinctive characteristics of ECPs appear to violate recognized accepted standards for safely and appropriately developing muscular fitness and are not uniformly aligned with established and accepted training doctrine. Accordingly, practical solutions to improve ECP prescription and implementation and reduce injury risk are of paramount importance.

  12. Effects of extreme habitat conditions on otolith morphology: a case study on extremophile live bearing fishes (Poecilia mexicana, P. sulphuraria).

    Science.gov (United States)

    Schulz-Mirbach, Tanja; Riesch, Rüdiger; García de León, Francisco J; Plath, Martin

    2011-12-01

    Our study was designed to evaluate if, and to what extent, restrictive environmental conditions affect otolith morphology. As a model, we chose two extremophile livebearing fishes: (i) Poecilia mexicana, a widespread species in various Mexican freshwater habitats, with locally adapted populations thriving in habitats characterized by the presence of one (or both) of the natural stressors hydrogen sulphide and darkness, and (ii) the closely related Poecilia sulphuraria living in a highly sulphidic habitat (Baños del Azufre). All three otolith types (lapilli, sagittae, and asterisci) of P. mexicana showed a decrease in size ranging from the non-sulphidic cave habitat (Cueva Luna Azufre), to non-sulphidic surface habitats, to the sulphidic cave (Cueva del Azufre), to sulphidic surface habitats (El Azufre), to P. sulphuraria. Although we found a distinct differentiation between ecotypes with respect to their otolith morphology, no clear-cut pattern of trait evolution along the two ecological gradients was discernible. Otoliths from extremophiles captured in the wild revealed only slight similarities to aberrant otoliths found in captive-bred fish. We therefore hypothesize that extremophile fishes have developed coping mechanisms enabling them to avoid aberrant otolith growth - an otherwise common phenomenon in fishes reared under stressful conditions. Copyright © 2011 Elsevier GmbH. All rights reserved.

  13. Human Performance under Extreme Conditions with Respect to a Resilient Organisation. Proceedings of a CSNI International Workshop, 24-26 February 2015, Brugg, Switzerland

    International Nuclear Information System (INIS)

    2015-01-01

    After the Fukushima Daiichi accident a number of initiatives have been undertaken internationally to learn from the accident and to implement lessons learned to improve nuclear safety. The accident has shown in particular the challenges in supporting reliable human performance under extreme conditions. Acknowledging that further work is needed to be better prepared for the HOF (Human and Organisational Factors) challenges of the extreme conditions that may be present in severe accidents, the NEA's Working Group on Human and Organisational Factors (WGHOF), one of the working groups for the Committee on the Safety of Nuclear Installations (CSNI) initiated a new task with the objectives to: - share experiences and knowledge of human and organisational performance under extreme conditions, - identify specific currently applied HOF principles in nuclear and other high risk industries and compare them with the available knowledge, - provide a basis for improvements and necessary research taking into account HOF issues in the design and use of measures, and - make recommendations with the aim to achieve the best level of human and organisational performance as possible under extreme conditions. In order to move those issues forward WGHOF hosted together with the Swiss Federal Nuclear Safety Inspectorate ENSI a workshop entitled 'Human Performance under Extreme Conditions with respect to a Resilient Organization'. The workshop was conducted with participation of a number of invited key speakers from academic research and a range of industries, including nuclear. Thirty-four experts from 12 countries, the IAEA and OECD/Halden participated. Experts came from nuclear authorities, research centres, technical support organisations, training simulator centres, utilities and from non-nuclear field (aircraft accident investigation, fire fighting, military, design of resilient organisations). From the discussions at the workshop, it is clear that the accident at Fukushima has

  14. Micro tectonic milonitas analysis in the extreme south of the Sarandi del Yi shear zone: Kinematics and deformation conditions

    International Nuclear Information System (INIS)

    Oyhantçabal, P; Suarez, I; Seluchi, N; Martinez, X.

    2010-01-01

    The Shear Zone divides Sarandi del Yi Craton River Plate in Piedra Alta and Nico Perez land . The southern end of this zone extends to north - south from the vicinity of the town of Minas to Punta Solis. The predominant lithology of the study area consists of a granitic mylonite with abundant muscovite and biotite. Structural data of foliation , stretching lineation and kinematic indicators were surveyed .Petrographic analysis shows that quartz is presented as ribbons polycrystalline product subgrain rotation recrystallization and grain boundary migration . Feldspar porphyroclasts are partially recrystallized in developing type structures c ore and mantle . Kinematic indicators such as sigma porphyroclasts , mica fish and oblique foliation defined consistently sinistral sense . The presence of stable and mirmequitas in the plane of biotite foliation along the microstructures described in quartz and feldspar , can be inferred temperature conditions between 450 ° C and 550° C during deformation

  15. Production of Secondary Metabolites in Extreme Environments: Food- and Airborne Wallemia spp. Produce Toxic Metabolites at Hypersaline Conditions

    DEFF Research Database (Denmark)

    Jančič, Sašo; Frisvad, Jens Christian; Kocev, Dragi

    2016-01-01

    the genome data analysis of W. mellicola (previously W. sebi sensu lato) and W. ichthyophaga revealed a low number of secondary metabolites clusters, a substantial number of secondary metabolites were detected at different conditions. Machine learning analysis of the obtained dataset showed that NaCl has...... of salt or sugar. In relation to food safety, the effect of high salt and sugar concentrations on the production of secondary metabolites by this toxigenic fungus was investigated. The secondary metabolite profiles of 30 strains of the listed species were examined using general growth media, known...... to support the production of secondary metabolites, supplemented with different concentrations of NaCl, glucose and MgCl2. In more than two hundred extracts approximately one hundred different compounds were detected using high-performance liquid chromatography-diode array detection (HPLC-DAD). Although...

  16. Frequency Analysis of Extreme Sub-Daily Precipitation under Stationary and Non-Stationary Conditions across Two Contrasting Hydroclimatic Environments

    Science.gov (United States)

    Demaria, E. M.; Goodrich, D. C.; Keefer, T.

    2017-12-01

    Observed sub-daily precipitation intensities from contrasting hydroclimatic environments in the USA are used to evaluate temporal trends and to develop Intensity-Duration Frequency (IDF) curves under stationary and nonstationary climatic conditions. Analyses are based on observations from two United States Department of Agriculture (USDA)-Agricultural Research Service (ARS) experimental watersheds located in a semi-arid and a temperate environment. We use an Annual Maximum Series (AMS) and a Partial Duration Series (PDS) approach to identify temporal trends in maximum intensities for durations ranging from 5- to 1440-minutes. A Bayesian approach with Monte Carlo techniques is used to incorporate the effect of non-stationary climatic assumptions in the IDF curves. The results show increasing trends in observed AMS sub-daily intensities in both watersheds whereas trends in the PDS observations are mostly positive in the semi-arid site and a mix of positive and negative in the temperate site. Stationary climate assumptions lead to much lower estimated sub-daily intensities than those under non-stationary assumptions with larger absolute differences found for shorter durations and smaller return periods. The risk of failure (R) of a hydraulic structure is increased for non-stationary effects over those of stationary effects, with absolute differences of 25% for a 100-year return period (T) and a project life (n) of 100 years. The study highlights the importance of considering non-stationarity, due to natural variability or to climate change, in storm design.

  17. Mild Traumatic Brain Injury

    Science.gov (United States)

    ... mild Traumatic Brain Injury Resilience Families with Kids Depression Families & Friendships Tobacco Life Stress Spirituality Anger Physical Injury Stigma Health & Wellness Work Adjustment Community Peer-2-Peer Forum ...

  18. Expert consensus on facilitators and barriers to return-to-work following surgery for non-traumatic upper extremity conditions: a Delphi study.

    Science.gov (United States)

    Peters, S E; Johnston, V; Ross, M; Coppieters, M W

    2017-02-01

    This Delphi study aimed to reach consensus on important facilitators and barriers for return-to-work following surgery for non-traumatic upper extremity conditions. In Round 1, experts ( n = 42) listed 134 factors, which were appraised in Rounds 2 and 3. Consensus (⩾85% agreement) was achieved for 13 facilitators (high motivation to return-to-work; high self-efficacy for return-to-work and recovery; availability of modified/alternative duties; flexible return-to-work arrangements; positive coping skills; limited heavy work exertion; supportive return-to-work policies; supportive supervisor/management; no catastrophic thinking; no fear avoidance to return-to-work; no fear avoidance to pain/activity; return to meaningful work duties; high job satisfaction) and six barriers (mood disorder diagnosis; pain/symptoms at more than one musculoskeletal site; heavy upper extremity exertions at work; lack of flexible return-to-work arrangements; lack of support from supervisor/management; high level of pain catastrophizing). Future prognostic studies are required to validate these biopsychosocial factors to further improve return-to-work outcomes. V.

  19. Validation of nonlinear FEA models of a thin-walled elbow under extreme loading conditions for Sodium-cooled Fast Reactors

    International Nuclear Information System (INIS)

    Watakabe, Tomoyoshi; Wakai, Takashi; Jin, Chuanrong; Usui, Yoshiya; Sakai, Shinkichi; Ooshika, Junji; Tsukimori, Kazuyuki

    2015-01-01

    For the purpose of confirming failure modes and safety margin, some studies on the ultimate strength of thin-walled piping components for Sodium-cooled Fast Reactors (SFRs) under extreme loading conditions such as large earthquakes have been reported these several years. Nonlinear finite element analysis has been applied in these studies to simulate buckling and yielding with large deformation, whose accuracy is dependent on the element type, the mesh size, the elasto-plastic model and so on. It is important to check the validation of a finite element model for nonlinear analysis especially under extreme loading conditions. This paper presents static and dynamic analyses of a thin-walled elbow with large deformation under large seismic loading, and discusses the validation of the FEA models comparing with experimental results. The finite element analysis models in this study are generated by shell elements for a stainless steel pipe elbow of diameter-to-thickness ratio 59:1 similar to the main pipe of SFRs, which is used for shaking table tests. At first, a static analysis is carried out for an in-plane monotonic bending test, in order to confirm that the shell element is appropriate to the large deformation analysis and the material parameters are proper for the strain level in the experiments. And then, a dynamic in-plane bending test with the maximum acceleration of 11.7G is simulated by the nonlinear FEA with stiffness-proportional damping. The influence of mesh sizes on results is investigated, to determine proper mesh sizes and reduce the computational cost. Finally, comparing the results of the FEM analyses with those of experiments, it is concluded that the appropriately generated FEA models are effective and give accurate results for nonlinear analyses of the thin-walled elbow under large seismic loading. (author)

  20. Mercury critical concentrations to Enchytraeus crypticus (Annelida: Oligochaeta) under normal and extreme conditions of moisture in tropical soils - Reproduction and survival.

    Science.gov (United States)

    Buch, Andressa Cristhy; Schmelz, Rüdiger M; Niva, Cintia Carla; Correia, Maria Elizabeth Fernandes; Silva-Filho, Emmanoel Vieira

    2017-05-01

    Soil provides many ecosystem services that are essential to maintain its quality and healthy development of the flora, fauna and human well-being. Environmental mercury levels may harm the survival and diversity of the soil fauna. In this respect, efforts have been made to establish limit values of mercury (Hg) in soils to terrestrial fauna. Soil organisms such as earthworms and enchytraeids have intimate contact with trace metals in soil by their oral and dermal routes, reflecting the potentially adverse effects of this contaminant. The main goal of this study was to obtain Hg critical concentrations under normal and extreme conditions of moisture in tropical soils to Enchytraeus crypticus to order to assess if climate change may potentiate their acute and chronic toxicity effects. Tropical soils were sampled from of two Forest Conservation Units of the Rio de Janeiro State - Brazil, which has been contaminated by Hg atmospheric depositions. Worms were exposed to three moisture conditions, at 20%, 50% and 80% of water holding capacity, respectively, and in combination with different Hg (HgCl 2 ) concentrations spiked in three types of tropical soil (two natural soils and one artificial soil). The tested concentrations ranged from 0 to 512mg Hg kg -1 dry weight. Results indicate that the Hg toxicity is higher under increased conditions of moisture, significantly affecting survival and reproduction rate. Copyright © 2017 Elsevier Inc. All rights reserved.

  1. Comparison and development of advanced dosimetric techniques to be used under extreme climatic conditions. Final report for the period 1 November 1971--28 December 1974

    Energy Technology Data Exchange (ETDEWEB)

    Madhvanath, U

    1975-08-01

    The post-irradiation fading characteristics of various dosimeters in function of relative humidity of air during storage were tested in specially set up humidity boxes. The temperature and relative humidity were varied between 5 and 35degC and 40-90%, respectively. Fading was 70% and 80% at 2 and 6 days respectively, for Kodak Type 2 film under 28degC and 76% relative humidity. Under these conditions the corresponding values for NTA emulsions were 30% and 80% respectively. Agfa-Gevaert films proved to be less sensitive and gave 20% and 30%, respectively, for the mentioned intervals. When Kodak Type 2 film was sealed in polythene bags, fading was reduced considerably, to appr. 15% in 4 weeks. Alternate storage of exposed films in humid and dry conditions also reduced fading to the same extent. When NTA emulsions were double-sealed with desiccant inside fading was reduced to 10% in 15 days. CaSO/sub 4/:Dy (DRP and Harshaw) showed only 7% fading in 3 months. LiF TLD-100 was more sensitive, 13% in 2 months. Gamma-irradiated Li-borate has faded up to 30% at extreme climatic conditions in 3 months but thermal neutron irradiated Li-borate was resistant against fading for this period.

  2. Sample size re-assessment leading to a raised sample size does not inflate type I error rate under mild conditions.

    Science.gov (United States)

    Broberg, Per

    2013-07-19

    One major concern with adaptive designs, such as the sample size adjustable designs, has been the fear of inflating the type I error rate. In (Stat Med 23:1023-1038, 2004) it is however proven that when observations follow a normal distribution and the interim result show promise, meaning that the conditional power exceeds 50%, type I error rate is protected. This bound and the distributional assumptions may seem to impose undesirable restrictions on the use of these designs. In (Stat Med 30:3267-3284, 2011) the possibility of going below 50% is explored and a region that permits an increased sample size without inflation is defined in terms of the conditional power at the interim. A criterion which is implicit in (Stat Med 30:3267-3284, 2011) is derived by elementary methods and expressed in terms of the test statistic at the interim to simplify practical use. Mathematical and computational details concerning this criterion are exhibited. Under very general conditions the type I error rate is preserved under sample size adjustable schemes that permit a raise. The main result states that for normally distributed observations raising the sample size when the result looks promising, where the definition of promising depends on the amount of knowledge gathered so far, guarantees the protection of the type I error rate. Also, in the many situations where the test statistic approximately follows a normal law, the deviation from the main result remains negligible. This article provides details regarding the Weibull and binomial distributions and indicates how one may approach these distributions within the current setting. There is thus reason to consider such designs more often, since they offer a means of adjusting an important design feature at little or no cost in terms of error rate.

  3. Mandelbrot's Extremism

    NARCIS (Netherlands)

    Beirlant, J.; Schoutens, W.; Segers, J.J.J.

    2004-01-01

    In the sixties Mandelbrot already showed that extreme price swings are more likely than some of us think or incorporate in our models.A modern toolbox for analyzing such rare events can be found in the field of extreme value theory.At the core of extreme value theory lies the modelling of maxima

  4. Efficient oxidative desulfurization (ODS) of model fuel with H{sub 2}O{sub 2} catalyzed by MoO{sub 3}/{gamma}-Al{sub 2}O{sub 3} under mild and solvent free conditions

    Energy Technology Data Exchange (ETDEWEB)

    Jia, Yuhua; Li, Gang; Ning, Guiling [State Key Laboratory of Fine Chemicals, School of Chemical Engineering, Dalian University of Technology (China)

    2011-01-15

    An efficient process to remove organic sulfur compounds from model fuel has been explored. Dibenzothiophene (DBT) and 4, 6-dimethyldibenzothiophene (4, 6-DMDBT) can be completely oxidized into their corresponding sulfones by H{sub 2}O{sub 2} over 14 wt.% MoO{sub 3}/{gamma}-Al{sub 2}O{sub 3} catalyst under mild conditions in 15 min. The effects of solvent, initial sulfide concentration, loading of MoO{sub 3} and amount of catalyst on oxidative removal of DBT were studied. The employments of solvents have decreased the reaction rate of DBT, which can be attributed to the competitive adsorption between the sulfide and solvent. The oxidative reactivity increases in the order of thiophene (Th) < benzothiophene (BT) < DBT < 4, 6-DMDBT. The catalyst can be regenerated by methanol washing at 333 K. (author)

  5. Industrial Coatings at Extreme Conditions

    DEFF Research Database (Denmark)

    Subramanian, Srinath; Pérez Hornero, Clara; Pedersen, Lars Thorslund

    With the gradual depletion of oil wells operable at relatively lower temperatures and pressures, the upstream oil industry relies on High Pressure High Temperature (HPHT) wells to source crude oil and gas. HPHT well extraction and processing require anticorrosive coatings applied on substrates...

  6. CO2 as a C1-organic building block: Enantioselective electrocarboxylation of aromatic ketones with CO2catalyzed by cinchona alkaloids under mild conditions

    International Nuclear Information System (INIS)

    Chen, Bao-Li; Tu, Zhuo-Ying; Zhu, Hong-Wei; Sun, Wen-Wen; Wang, Huan; Lu, Jia-Xing

    2014-01-01

    Highlights: •Cinchona alkaloids catalysis achieve enantioselective electrocarboxylation of racemic aromatic ketones. •The applications of CO 2 enantioselective electrochemical fixation into optically active hydroxyl carboxylic acids have been expanded. •The applications of alkaloids have been expanded. •The applications of asymmetric synthesis by electrochemical methodology have been expanded. -- Abstract: The enantioselective electrocarboxylation of pro-chiral aromatic ketones (2-acetonaphthone, 1-(6-methoxy-2-naphthyl)ethanone, 1-(4-methoxy-1-naphthyl)ethanone) with atmospheric pressure of CO 2 catalyzed by cinchona alkaloids in the presence of phenol was investigated in an undivided cell for the first time to give optically active 2-hydroxy-2-arylpropionic acid. For the model compound 2-acetonaphthone, the influence of various reaction conditions, such as cathode material, current density, catalyst type, ratio of proton to catalyst and catalyst quantity, on the enantiomeric excesses (ee) and yield has been investigated. Under the optimized conditions of 2-acetonaphthone, all the aromatic ketones examined are converted into corresponding optically active 2-hydroxy-2-arylpropionic acids in moderate yield (32.2% - 41.3%) and ee (48.1% - 48.6%). In addition, the electrochemical behavior of 2-acetonaphthone has been studied by cyclic voltammetry (CV) in the absence and presence of CO 2 . Moreover, the probable reaction pathway was proposed accordingly

  7. Macrodynamic study and catalytic reduction of NO by ammonia under mild conditions over Pt-La-Ce-O/Al2O3 catalysts

    International Nuclear Information System (INIS)

    Wang, Yanhui; Zhu, Jingli; Ma, Runyu

    2007-01-01

    Catalytic reduction of NO using ammonia upon series prepared catalysts under 423-573 K in a fixed bed reactor was investigated. Results showed that the performance of supported platinum catalyst could be improved by addition of La and Ce to it. Experimental studies indicated that the suitable molar ratio of Pt:La:Ce would be 1.0:3.78:3.56, Pt-La-Ce (c). Results also found Pt-La-Ce (c) catalyst had good stability and tolerance to certain amounts of sulfur compounds under the used experimental conditions. Characterization for the fresh and used catalysts showed the Pt-La-Ce (c) catalyst had a stable structure. In addition, based on experimental data and using a nonlinear regression algorithm method, an empirical macrodynamic equation was obtained in this study

  8. Thermal science under extreme conditions. Proceedings of the annual congress of the French Society of Thermal science - SFT 2012, 29 May-1 June, Bordeaux-Talence

    International Nuclear Information System (INIS)

    Gendrhi, Philippe; Perrin, Bernard; Journeau, Christophe; MOST, Jean-Michel; Nicolai, Philippe

    2012-06-01

    This publication proposes the contributions made during plenary sessions, and those made on various themes (Multi-physical couplings combustion; Contacts and interfaces; Natural, hybrid and forced convection, Energy and the environment; High temperatures and high flows; Metrology and identification; Micro- and nano-thermal science; Radiation; Control of systems and thermal process; System thermal science; Life thermal science; Transfer in multi-phase media; Transfer in porous media). Among the plenary session conferences some authors more particularly addressed the following issues: Thermal science at the heart of thermonuclear fusion (presentation of thermonuclear fusion by magnetic confinement); Thermal science of severe accidents of nuclear reactors (study of the thermal science of corium-water interaction which could result in a thermal detonation, study of corium baths at the vessel bottom or in interaction with the vessel well concrete, proposition of technological solutions for corium recovery); Fusion by inertial confinement and associated energy exchanges (case of inertial confinement by power lasers, presentation of needed conditions to obtain an energetic gain, of different energy and heat transfers under extreme conditions)

  9. Psychological and psycho-vegetative technologies of diagnostics and correction the behavior of professionals working in extreme conditions (state of problem and prospective studies

    Directory of Open Access Journals (Sweden)

    Bulygina V.G.

    2016-10-01

    Full Text Available The article is devoted to promising areas of research regulatory processes (self-control оf the professionals working in special and extreme conditions of professional activity. The actuality of creation a comprehensive compact of the selection methods, adaptation the technologies to professional tasks, methods of psychological assistance of the specialists of hazardous occupations was shown. It was done an overview of foreign studies of the features of psychological regulation and self-control in stressful situations, neurophysiological correlates of self-control and aggressive behavior. The results of trainings of the development of the capacity for self-control, increasing resistance to the negative effects of mental exhaustion, were described. There were expounded the results of domestic investigations of the association between the self-regulation of behavior and profile of reactivity among mentally healthy and ill persons. The necessity of the development of psychodiagnostic and psychological programs for specialists in the professions of risk, aimed to improve the efficiency of regulatory processes for the adaptation to the conditions of professional activity.

  10. Evaluation of a lateral flow-based technology card for blood typing using a simplified protocol in a model of extreme blood sampling conditions.

    Science.gov (United States)

    Clavier, Benoît; Pouget, Thomas; Sailliol, Anne

    2018-02-01

    Life-threatening situations requiring blood transfusion under extreme conditions or in remote and austere locations, such as the battlefield or in traffic accidents, would benefit from reliable blood typing practices that are easily understood by a nonscientist or nonlaboratory technician and provide quick results. A simplified protocol was developed for the lateral flow-based device MDmulticard ABO-D-Rh subgroups-K. Its performance was compared to a reference method (PK7300, Beckman Coulter) in native blood samples from donors. The method was tested on blood samples stressed in vitro as a model of hemorrhage cases (through hemodilution using physiologic serum) and dehydration (through hemoconcentration by removing an aliquot of plasma after centrifugation), respectively. A total of 146 tests were performed on 52 samples; 126 in the hemodilution group (42 for each native, diluted 1/2, and diluted 1/4 samples) and 20 in the hemoconcentration group (10 for each native and 10% concentrated samples). Hematocrit in the tested samples ranged from 9.8% to 57.6% while hemoglobin levels ranged from 3.2 to 20.1 g/dL. The phenotype profile detected with the MDmulticard using the simplified protocol resulted in 22 A, seven B, 20 O, and three AB, of which nine were D- and five were Kell positive. No discrepancies were found with respect to the results obtained with the reference method. The simplified protocol for MDmulticard use could be considered a reliable method for blood typing in extreme environment or emergency situations, worsened by red blood cell dilution or concentration. © 2017 AABB.

  11. Correlation of denitrification-accepted fraction of electrons with NAD(P)H fluorescence for Pseudomonas aeruginosa performing simultaneous denitrification and respiration at extremely low dissolved oxygen conditions.

    Science.gov (United States)

    Chen, Fan; Xia, Qing; Ju, Lu-Kwang

    2004-01-01

    In cystic fibrosis airway infection, Pseudomonas aeruginosa forms a microaerobic biofilm and undergoes significant physiological changes. It is important to understand the bacterium's metabolism at microaerobic conditions. In this work, the culture properties and two indicators (the denitrification-accepted e- fraction and an NAD(P)H fluorescence fraction) for the culture's "fractional approach" to a fully anaerobic denitrifying state were examined in continuous cultures with practically zero DO but different aeration rates. With decreasing aeration, specific OUR decreased while specific NAR and NIR increased and kept Y(ATP/S) relatively constant. P. aeruginosa thus appeared to effectively compensate for energy generation at microaerobic conditions with denitrification. At the studied dilution rate of 0.06 h(-1), the maximum specific OUR was 2.8 mmol O2/g cells-h and the Monod constant for DO, in the presence of nitrate, was extremely low (Y(X/S) increased significantly (from 0.24 to 0.34) with increasing aeration, attributed to a roughly opposite trend of Y(ATP/X) (ATP generation required for cell growth). As for the denitrification-accepted e- fraction and the fluorescence fraction, both decreased with increasing aeration as expected. The two fractions, however, were not directly proportional. The fluorescence fraction changed more rapidly than the e- fraction at very low aeration rates, whereas the opposite was true at higher aeration. The results demonstrated the feasibility of using online NAD(P)H fluorescence to monitor sensitive changes of cellular physiology and provided insights to the shift of e- -accepting mechanisms of P. aeruginosa under microaerobic conditions.

  12. Extremal surface barriers

    International Nuclear Information System (INIS)

    Engelhardt, Netta; Wall, Aron C.

    2014-01-01

    We present a generic condition for Lorentzian manifolds to have a barrier that limits the reach of boundary-anchored extremal surfaces of arbitrary dimension. We show that any surface with nonpositive extrinsic curvature is a barrier, in the sense that extremal surfaces cannot be continuously deformed past it. Furthermore, the outermost barrier surface has nonnegative extrinsic curvature. Under certain conditions, we show that the existence of trapped surfaces implies a barrier, and conversely. In the context of AdS/CFT, these barriers imply that it is impossible to reconstruct the entire bulk using extremal surfaces. We comment on the implications for the firewall controversy

  13. Rhizosphere bacteria of Costularia spp. from ultramafic soils in New Caledonia: diversity, tolerance to extreme edaphic conditions, and role in plant growth and mineral nutrition.

    Science.gov (United States)

    Gonin, Mathieu; Gensous, Simon; Lagrange, Alexandre; Ducousso, Marc; Amir, Hamid; Jourand, Philippe

    2013-03-01

    Rhizosphere bacteria were isolated from Costularia spp., pioneer sedges from ultramafic soils in New Caledonia, which is a hotspot of biodiversity in the South Pacific. Genus identification, ability to tolerate edaphic constraints, and plant-growth-promoting (PGP) properties were analysed. We found that 10(5) colony-forming units per gram of root were dominated by Proteobacteria (69%) and comprised 21 genera, including Burkholderia (28%), Curtobacterium (15%), Bradyrhizobium (9%), Sphingomonas (8%), Rhizobium (7%), and Bacillus (5%). High proportions of bacteria tolerated many elements of the extreme edaphic conditions: 82% tolerated 100 μmol·L(-1) chromium, 70% 1 mmol·L(-1) nickel, 63% 10 mmol·L(-1) manganese, 24% 1 mmol·L(-1) cobalt, and 42% an unbalanced calcium/magnesium ratio (1/16). These strains also exhibited multiple PGP properties, including the ability to produce ammonia (65%), indole-3-acetic acid (60%), siderophores (52%), and 1-aminocyclopropane-1-carboxylate (ACC) deaminase (39%); as well as the capacity to solubilize phosphates (19%). The best-performing strains were inoculated with Sorghum sp. grown on ultramafic substrate. Three strains significantly enhanced the shoot biomass by up to 33%. The most successful strains influenced plant nutrition through the mobilization of metals in roots and a reduction of metal transfer to shoots. These results suggest a key role of these bacteria in plant growth, nutrition, and adaptation to the ultramafic constraints.

  14. The genomic sequence of Exiguobacterium chiriqhucha str. N139 reveals a species that thrives in cold waters and extreme environmental conditions

    Directory of Open Access Journals (Sweden)

    Ana Gutiérrez-Preciado

    2017-04-01

    Full Text Available We report the genome sequence of Exiguobacterium chiriqhucha str. N139, isolated from a high-altitude Andean lake. Comparative genomic analyses of the Exiguobacterium genomes available suggest that our strain belongs to the same species as the previously reported E. pavilionensis str. RW-2 and Exiguobacterium str. GIC 31. We describe this species and propose the chiriqhucha name to group them. ‘Chiri qhucha’ in Quechua means ‘cold lake’, which is a common origin of these three cosmopolitan Exiguobacteria. The 2,952,588-bp E. chiriqhucha str. N139 genome contains one chromosome and three megaplasmids. The genome analysis of the Andean strain suggests the presence of enzymes that confer E. chiriqhucha str. N139 the ability to grow under multiple environmental extreme conditions, including high concentrations of different metals, high ultraviolet B radiation, scavenging for phosphorous and coping with high salinity. Moreover, the regulation of its tryptophan biosynthesis suggests that novel pathways remain to be discovered, and that these pathways might be fundamental in the amino acid metabolism of the microbial community from Laguna Negra, Argentina.

  15. Single-crystal diffraction at the Extreme Conditions beamline P02.2: procedure for collecting and analyzing high-pressure single-crystal data.

    Science.gov (United States)

    Rothkirch, André; Gatta, G Diego; Meyer, Mathias; Merkel, Sébastien; Merlini, Marco; Liermann, Hanns Peter

    2013-09-01

    Fast detectors employed at third-generation synchrotrons have reduced collection times significantly and require the optimization of commercial as well as customized software packages for data reduction and analysis. In this paper a procedure to collect, process and analyze single-crystal data sets collected at high pressure at the Extreme Conditions beamline (P02.2) at PETRA III, DESY, is presented. A new data image format called `Esperanto' is introduced that is supported by the commercial software package CrysAlis(Pro) (Agilent Technologies UK Ltd). The new format acts as a vehicle to transform the most common area-detector data formats via a translator software. Such a conversion tool has been developed and converts tiff data collected on a Perkin Elmer detector, as well as data collected on a MAR345/555, to be imported into the CrysAlis(Pro) software. In order to demonstrate the validity of the new approach, a complete structure refinement of boron-mullite (Al5BO9) collected at a pressure of 19.4 (2) GPa is presented. Details pertaining to the data collections and refinements of B-mullite are presented.

  16. Stakeholders identify similar barriers but different strategies to facilitate return-to-work: A vignette of a worker with an upper extremity condition.

    Science.gov (United States)

    Peters, Susan E; Truong, Anthony P; Johnston, Venerina

    2018-01-01

    Stakeholders involved in the return-to-work (RTW) process have different roles and qualificationsOBJECTIVE:To explore the perspectives of Australian stakeholders of the RTW barriers and strategies for a worker with an upper extremity condition and a complex workers' compensation case. Using a case vignette, stakeholders were asked to identify barriers and recommend strategies to facilitate RTW. Content analysis was performed on the open-ended responses. The responses were categorised into RTW barriers and strategies using the biopsychosocial model. Pearson's Chi Square and ANOVA were performed to establish group differences. 621 participants (488 healthcare providers (HCPs), 62 employers, 55 insurers and 16 lawyers) identified 36 barriers (31 modifiable): 4 demographic; 8 biological; 15 psychological and 9 social barriers. 484 participants reported 16 RTW strategies: 4 biological; 6 psychological and 6 social strategies. 'Work relationship stressors' (83.4%) and 'Personal relationship stressors' (64.7%) were the most frequently nominated barriers. HCPs most frequently nominated 'Pain management' (49.6%), while employers, insurers and lawyers nominated 'RTW planning/Suitable duties programs' (40.5%; 42.9%; 80%). Stakeholders perceived similar barriers for RTW but recommended different strategies. Stakeholders appeared to be more proficient in identifying barriers than recommending strategies. Future research should focus on tools to both identify RTW barriers and direct intervention.

  17. Interim evaluation report on research and development of robots serviceable under extreme conditions; Kyokugen sagyo robot no kenkyu kaihatsu chukan hyoka hokokusho

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1988-03-01

    The research and development project for robots serviceable under extreme conditions are aimed at development of the robots for commercial nuclear power plants, where they are remotely controlled by the operators to implement advanced works, e.g., maintenance, inspection and repair of the facilities; supporting development of submarine oil fields, where they are remotely controlled by the operators to implement advanced works, e.g., maintenance, inspection and repair of the facilities; and for prevention of hazards at oil-producing plants, where they are remotely controlled by the operators to implement advanced works, e.g., controlling hazards, should they occur, and supporting hazard-preventive works. It is also aimed at development of the basic techniques for, e.g., those related to the system structures, and controlling and supporting the other systems. The project has been comprehensively evaluated for the achievements made so far. The individual elementary techniques for the robots for nuclear power plants, submarine oil field development and hazard prevention, and the basic techniques for these systems, are developed as planned as of the end of FY 1987 for the objects in the interim stage, based on the evaluation of the individual techniques developed before. Therefore, the bright prospects are obtained for achieving the final objectives by the end of the project period. (NEDO)

  18. Extreme cosmos

    CERN Document Server

    Gaensler, Bryan

    2011-01-01

    The universe is all about extremes. Space has a temperature 270°C below freezing. Stars die in catastrophic supernova explosions a billion times brighter than the Sun. A black hole can generate 10 million trillion volts of electricity. And hypergiants are stars 2 billion kilometres across, larger than the orbit of Jupiter. Extreme Cosmos provides a stunning new view of the way the Universe works, seen through the lens of extremes: the fastest, hottest, heaviest, brightest, oldest, densest and even the loudest. This is an astronomy book that not only offers amazing facts and figures but also re

  19. Structural comparison of tRNA m1A58 methyltransferases revealed different molecular strategies to maintain their oligomeric architecture under extreme conditions

    Directory of Open Access Journals (Sweden)

    Guelorget Amandine

    2011-12-01

    Full Text Available Abstract Background tRNA m1A58 methyltransferases (TrmI catalyze the transfer of a methyl group from S-adenosyl-L-methionine to nitrogen 1 of adenine 58 in the T-loop of tRNAs from all three domains of life. The m1A58 modification has been shown to be essential for cell growth in yeast and for adaptation to high temperatures in thermophilic organisms. These enzymes were shown to be active as tetramers. The crystal structures of five TrmIs from hyperthermophilic archaea and thermophilic or mesophilic bacteria have previously been determined, the optimal growth temperature of these organisms ranging from 37°C to 100°C. All TrmIs are assembled as tetramers formed by dimers of tightly assembled dimers. Results In this study, we present a comparative structural analysis of these TrmIs, which highlights factors that allow them to function over a large range of temperature. The monomers of the five enzymes are structurally highly similar, but the inter-monomer contacts differ strongly. Our analysis shows that bacterial enzymes from thermophilic organisms display additional intermolecular ionic interactions across the dimer interfaces, whereas hyperthermophilic enzymes present additional hydrophobic contacts. Moreover, as an alternative to two bidentate ionic interactions that stabilize the tetrameric interface in all other TrmI proteins, the tetramer of the archaeal P. abyssi enzyme is strengthened by four intersubunit disulfide bridges. Conclusions The availability of crystal structures of TrmIs from mesophilic, thermophilic or hyperthermophilic organisms allows a detailed analysis of the architecture of this protein family. Our structural comparisons provide insight into the different molecular strategies used to achieve the tetrameric organization in order to maintain the enzyme activity under extreme conditions.

  20. Mild Cognitive Impairment

    Science.gov (United States)

    ... more: Key Types of Dementia , What Is Alzheimer's? , Alzheimer's Risk Factors Symptoms back to top Experts classify Mild cognitive ... in Chronic Traumatic Encephalopathy 2014 Thor Stein Genetic Risk Factors Underlying Chronic Trauma and Alzheimer's Disease Pathology 2014 Kun Ping Lu Validation of ...

  1. Computer system for the assessment of radiation situation in the cases of radiological accidents and extreme weather conditions in the Chernobyl exclusion zone

    Energy Technology Data Exchange (ETDEWEB)

    Talerko, M.; Garger, E.; Kuzmenko, A. [Institute for Safety Problems of Nuclear Power Plants (Ukraine)

    2014-07-01

    Radiation situation within the Chernobyl Exclusion Zone (ChEZ) is determined by high radionuclides contamination of the land surface formed after the 1986 accident, as well as the presence of a number of potentially hazardous objects (the 'Shelter' object, the Interim Spent Nuclear Fuel Dry Storage Facility ISF-1, radioactive waste disposal sites, radioactive waste temporary localization sites etc.). The air concentration of radionuclides over the ChEZ territory and radiation exposure of personnel are influenced by natural and anthropogenic factors: variable weather conditions, forest fires, construction and excavation activity etc. The comprehensive radiation monitoring and early warning system in the ChEZ was established under financial support of European Commission in 2011. It involves the computer system developed for assessment and prediction of radiological emergencies consequences in the ChEZ ensuring the protection of personnel and the population living near its borders. The system assesses radiation situation under both normal conditions in the ChEZ and radiological emergencies which result in considerable radionuclides emission into the air (accidents at radiation hazardous objects, extreme weather conditions). Three different types of radionuclides release sources can be considered in the software package. So it is based on a set of different models of emission, atmospheric transport and deposition of radionuclides: 1) mesoscale model of radionuclide atmospheric transport LEDI for calculations of the radionuclides emission from stacks and buildings; 2) model of atmospheric transport and deposition of radionuclides due to anthropogenic resuspension from contaminated area (area surface source model) as a result of construction and excavation activity, heavy traffic etc.; 3) model of resuspension, atmospheric transport and deposition of radionuclides during grassland and forest fires in the ChEZ. The system calculates the volume and surface

  2. Waste Material Based "Terrazzo" Tiles: The Effect Of Curing Time And Extreme Environmental Conditions Over Glass Aggregate/Cement Matrix Boundary

    Science.gov (United States)

    Paris, E.; Radica, F.; Stabile, P.; Ansaloni, F.; Giuli, G.; Carroll, M. R.

    2017-12-01

    Currently, more than half of all materials extracted globally (over three billion tonnes/year in the EU only) are transformed for use in construction. Before year 2020, the EU aims to reduce the environmental impact of the construction sector by recycling or re-using large amounts of these materials, thus reducing the consumption of raw materials and helping promote the sector's economic stability. With this challenge in mind an aesthetically pleasant and fully recycled (up to 78%) pre-cast cement based tile (Terrazzo tiles) was designed by replacing raw materials with Glass Waste (GW) and Construction/Demolition Waste (CDW). Several recent studies explored the effect of the addition of GW in the manufacture of urban pavements, concluding that the use of GW can improve various phases of pavement life and structure by enhancing the structural performance, durability, environmental friendliness, and aesthetic features. In this study we extend this knowledge also to interior cement-based tiles by evaluating the technical performances of this this novel designed tile, in particular by focusing on the interface between the GW aggregates and different Portland cement based matrix at extreme environmental conditions. For this work three representative waste material based "terrazzo" tiles were selected and characterized by means of XRD and SEM imaging in order to study the boundary effect between GW aggregate and different binding materials: limestone powder, quartz powder and fine ground WG powder. A fourth additional mixture of Portland cement and CDW material was characterized. Fragments of a Limestone matrix tile were also thermally threated at -18°C and at 60°C for one week to witness the possible formation of new harmful phases at the grain-matrix boundary. Preliminary results on X-ray diffraction patterns show that 1 year after manufacture and/or thermal treatment there is no new formation of harmful phases other than the starting ones. High magnification SEM

  3. Mild induced hypothermia

    DEFF Research Database (Denmark)

    Johansen, Maria E; Jensen, Jens-Ulrik; Bestle, Morten H

    2014-01-01

    INTRODUCTION: Coagulopathy associates with poor outcome in sepsis. Mild induced hypothermia has been proposed as treatment in sepsis but it is not known whether this intervention worsens functional coagulopathy. MATERIALS AND METHODS: Interim analysis data from an ongoing randomized controlled...... trial; The Cooling And Surviving Septic shock (CASS) study. Patients suffering severe sepsis/septic shock are allocated to either mild induced hypothermia (cooling to 32-34°C for 24hours) or control (uncontrolled temperature). TRIAL REGISTRATION: NCT01455116. Thrombelastography (TEG) is performed three....... At enrollment, 3%, 38%, and 59% had a hypocoagulable, normocoagulable, and hypercoagulable TEG clot strength (MA), respectively. In the hypothermia group, functional coagulopathy improved during the hypothermia phase, measured by R and MA, in patients with hypercoagulation as well as in patients...

  4. Suppressing the Photocatalytic Activity of TiO2 Nanoparticles by Extremely Thin Al2O3 Films Grown by Gas-Phase Deposition at Ambient Conditions

    NARCIS (Netherlands)

    Guo, J.; Bui, H.V.; Valdesueiro Gonzalez, D.; Yuan, Shaojun; Liang, Bin; van Ommen, J.R.

    2018-01-01

    This work investigated the suppression of photocatalytic activity of titanium dioxide (TiO2) pigment powders by extremely thin aluminum oxide (Al2O3) films deposited via an atomic-layer-deposition-type process using trimethylaluminum (TMA) and H2O as precursors. The deposition was performed on

  5. The Behavior of Hydrogen Under Extreme Conditions on Ultrafast Timescales (A 'Life at the Frontiers of Energy Research' contest entry from the 2011 Energy Frontier Research Centers (EFRCs) Summit and Forum)

    International Nuclear Information System (INIS)

    Mao, Ho-kwang

    2011-01-01

    'The Behavior of Hydrogen Under Extreme Conditions on Ultrafast Timescales ' was submitted by the Center for Energy Frontier Research in Extreme Environments (EFree) to the 'Life at the Frontiers of Energy Research' video contest at the 2011 Science for Our Nation's Energy Future: Energy Frontier Research Centers (EFRCs) Summit and Forum. Twenty-six EFRCs created short videos to highlight their mission and their work. EFree is directed by Ho-kwang Mao at the Carnegie Institute of Washington and is a partnership of scientists from thirteen institutions.The Office of Basic Energy Sciences in the U.S. Department of Energy's Office of Science established the 46 Energy Frontier Research Centers (EFRCs) in 2009. These collaboratively-organized centers conduct fundamental research focused on 'grand challenges' and use-inspired 'basic research needs' recently identified in major strategic planning efforts by the scientific community. The overall purpose is to accelerate scientific progress toward meeting the nation's critical energy challenges. The mission of Energy Frontier Research in Extreme Environments is 'to accelerate the discovery and creation of energy-relevant materials using extreme pressures and temperatures.' Research topics are: catalysis (CO 2 , water), photocatalysis, solid state lighting, optics, thermelectric, phonons, thermal conductivity, solar electrodes, fuel cells, superconductivity, extreme environment, radiation effects, defects, spin dynamics, CO 2 (capture, convert, store), greenhouse gas, hydrogen (fuel, storage), ultrafast physics, novel materials synthesis, and defect tolerant materials.

  6. Acclimatization to extreme heat

    Science.gov (United States)

    Warner, M. E.; Ganguly, A. R.; Bhatia, U.

    2017-12-01

    Heat extremes throughout the globe, as well as in the United States, are expected to increase. These heat extremes have been shown to impact human health, resulting in some of the highest levels of lives lost as compared with similar natural disasters. But in order to inform decision makers and best understand future mortality and morbidity, adaptation and mitigation must be considered. Defined as the ability for individuals or society to change behavior and/or adapt physiologically, acclimatization encompasses the gradual adaptation that occurs over time. Therefore, this research aims to account for acclimatization to extreme heat by using a hybrid methodology that incorporates future air conditioning use and installation patterns with future temperature-related time series data. While previous studies have not accounted for energy usage patterns and market saturation scenarios, we integrate such factors to compare the impact of air conditioning as a tool for acclimatization, with a particular emphasis on mortality within vulnerable communities.

  7. Stochastic Modeling of Long-Term and Extreme Value Estimation of Wind and Sea Conditions for Probabilistic Reliability Assessments of Wave Energy Devices

    DEFF Research Database (Denmark)

    Ambühl, Simon; Kofoed, Jens Peter; Sørensen, John Dalsgaard

    2014-01-01

    Wave energy power plants are expected to become one of the major future contribution to the sustainable electricity production. Optimal design of wave energy power plants is associated with modeling of physical, statistical, measurement and model uncertainties. This paper presents stochastic models...... for the significant wave height, the mean zero-crossing wave period and the wind speed for long-term and extreme estimations. The long-term estimation focuses on annual statistical distributions, the inter-annual variation of distribution parameters and the statistical uncertainty due to limited amount of data...

  8. Pharmacotherapy for mild hypertension

    Directory of Open Access Journals (Sweden)

    Diana Diao

    2012-01-01

    Full Text Available BACKGROUND: People with no previous cardiovascular events or cardiovascular disease represent a primary prevention population. The benefits and harms of treating mild hypertension in primary prevention patients are not known at present. This review examines the existing randomized controlled trial (RCT evidence. OBJECTIVE: Primary objective: To quantify the effects of antihypertensive drug therapy on mortality and morbidity in adults with mild hypertension (systolic blood pressure (BP 140-159 mmHg and/or diastolic BP 90-99 mmHg and without cardiovascular disease. METHODS: Search: We searched CENTRAL (2011, Issue 1, MEDLINE (1948 to May 2011, EMBASE (1980 to May 2011 and reference lists of articles. The Cochrane Database of Systematic Reviews and the Database of Abstracts of Reviews of Effectiveness (DARE were searched for previous reviews and meta-analyses of anti-hypertensive drug treatment compared to placebo or no treatment trials up until the end of 2011. Selection criteria: RCTs of at least 1 year duration. Data collection and analysis: The outcomes assessed were mortality, stroke, coronary heart disease (CHD, total cardiovascular events (CVS, and withdrawals due to adverse effects. MAIN RESULTS: Of 11 RCTs identified 4 were included in this review, with 8,912 participants. Treatment for 4 to 5 years with antihypertensive drugs as compared to placebo did not reduce total mortality (RR 0.85, 95% CI 0.63, 1.15. In 7,080 participants treatment with antihypertensive drugs as compared to placebo did not reduce coronary heart disease (RR 1.12, 95% CI 0.80, 1.57, stroke (RR 0.51, 95% CI 0.24, 1.08, or total cardiovascular events (RR 0.97, 95% CI 0.72, 1.32. Withdrawals due to adverse effects were increased by drug therapy (RR 4.80, 95% CI 4.14, 5.57, ARR 9%. AUTHORS' CONCLUSIONS: Antihypertensive drugs used in the treatment of adults (primary prevention with mild hypertension (systolic BP 140-159 mmHg and/or diastolic BP 90-99 mmHg have not been

  9. Reduced brachial flow-mediated vasodilation in young adult ex extremely low birth weight preterm: a condition predictive of increased cardiovascular risk?

    Science.gov (United States)

    Bassareo, P P; Fanos, V; Puddu, M; Demuru, P; Cadeddu, F; Balzarini, M; Mercuro, G

    2010-10-01

    Sporadic data present in literature report how preterm birth and low birth weight constitute the risk factors for the development of cardiovascular diseases in later life. To assess the presence of potential alterations to endothelial function in young adults born preterm at extremely low birth weight (Cesarea, Israel). Endothelial function was significantly reduced in ex-ELBW subjects compared to C (1.94 +/- 0.37 vs. 2.68 +/- 0.41, p < 0.0001). Moreover, this function correlated significantly with gestational age (r = 0.56, p < 0.0009) and birth weight (r = 0.63, p < 0.0001). The results obtained reveal a significant decrease in endothelial function of ex-ELBW subjects compared to controls, underlining a probable correlation with preterm birth and low birth weight. Taken together, these results suggest that an ELBW may underlie the onset of early circulatory dysfunction predictive of increased cardiovascular risk.

  10. Photocatalysis of the homogeneous water-gas shift reaction under ambient conditions by cationic iridium (III) complexes

    Energy Technology Data Exchange (ETDEWEB)

    Ziessel, R [Ecole Europeenne des Hautes Etudes des Industries Chimiques, 67 - Strasbourg (France)

    1991-07-01

    We describe here our results and mechanistic analysis of the first highly efficient light-assisted WGSR, which takes place under extremely mild conditions (room temperature, ambient pressure, neutral pH, visible light) and is catalyzed by novel Ir{sup III} pentamethylcyclopentadienyl complexes containing novel 4,4'-substituted bipyridine ligands. (orig./EF).

  11. Frequently Asked Questions (FAQ) about Extreme Heat

    Science.gov (United States)

    ... Extreme Heat Older Adults (Aged 65+) Infants and Children Chronic Medical Conditions Low Income Athletes Outdoor Workers Pets Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ...

  12. Suppressing the Photocatalytic Activity of TiO2 Nanoparticles by Extremely Thin Al2O3 Films Grown by Gas-Phase Deposition at Ambient Conditions

    Directory of Open Access Journals (Sweden)

    Jing Guo

    2018-01-01

    Full Text Available This work investigated the suppression of photocatalytic activity of titanium dioxide (TiO2 pigment powders by extremely thin aluminum oxide (Al2O3 films deposited via an atomic-layer-deposition-type process using trimethylaluminum (TMA and H2O as precursors. The deposition was performed on multiple grams of TiO2 powder at room temperature and atmospheric pressure in a fluidized bed reactor, resulting in the growth of uniform and conformal Al2O3 films with thickness control at sub-nanometer level. The as-deposited Al2O3 films exhibited excellent photocatalytic suppression ability. Accordingly, an Al2O3 layer with a thickness of 1 nm could efficiently suppress the photocatalytic activities of rutile, anatase, and P25 TiO2 nanoparticles without affecting their bulk optical properties. In addition, the influence of high-temperature annealing on the properties of the Al2O3 layers was investigated, revealing the possibility of achieving porous Al2O3 layers. Our approach demonstrated a fast, efficient, and simple route to coating Al2O3 films on TiO2 pigment powders at the multigram scale, and showed great potential for large-scale production development.

  13. Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship.

    Science.gov (United States)

    Scott, Alison J; Oyler, Benjamin L; Goodlett, David R; Ernst, Robert K

    2017-11-01

    Strategies utilizing Toll-like receptor 4 (TLR4) agonists for treatment of cancer, infectious diseases, and other targets report promising results. Potent TLR4 antagonists are also gaining attention as therapeutic leads. Though some principles for TLR4 modulation by lipid A have been described, a thorough understanding of the structure-activity relationship (SAR) is lacking. Only through a complete definition of lipid A-TLR4 SAR is it possible to predict TLR4 signaling effects of discrete lipid A structures, rendering them more pharmacologically relevant. A limited 'toolbox' of lipid A-modifying enzymes has been defined and is largely composed of enzymes from mesophile human and zoonotic pathogens. Expansion of this 'toolbox' will result from extending the search into lipid A biosynthesis and modification by bacteria living at the extremes. Here, we review the fundamentals of lipid A structure, advances in lipid A uses in TLR4 modulation, and the search for novel lipid A-modifying systems in extremophile bacteria. This article is part of a Special Issue entitled: Bacterial Lipids edited by Russell E. Bishop. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Lower extremity injury in female basketball players is related to a large difference in peak eversion torque between barefoot and shod conditions

    Directory of Open Access Journals (Sweden)

    Jennifer M. Yentes

    2014-09-01

    Conclusion: It is possible that a large discrepancy between strength in barefoot and shod conditions can predispose an athlete to injury. Narrowing the difference in peak eversion torque between barefoot and shod could decrease propensity to injury. Future work should investigate the effect of restoration of muscular strength during barefoot and shod exercise on injury rates.

  15. Suicide of Women: an Extreme Condition? Suicidio de mujeres: ¿un caso extremo? Suicídio de Mulheres: uma Situação Limite?

    Directory of Open Access Journals (Sweden)

    Stela Meneghel

    2013-07-01

    Full Text Available Suicide, understood as a social fact, can be considered an extreme situation that represents a way out of an intense and unbearable suffering. This text reflects on the fragility of gender present in the life stories of women who committed suicide in cities in southern Brazil. Qualitative study that is part of a larger study entitled "It's possible to prevent the advance of the end? elderly suicide in Brazil and possibilities of health sector". The data were constructed using the technique of psychosocial autopsy trying to understand the life histories and factors related to suicide. The main themes present in the life stories of suicide women were classified as gender vulnerability and suicide as an extreme situation. We believe that gender norms, interpersonal conflicts and economic problems arising from work and illness were present in the lives of these women.  El suicidio, entendido como un hecho social, puede considerarse una situación extrema, ya que representa una forma de salir de un sufrimiento intenso e insoportable. Este texto tiene como objetivo reflexionar sobre la fragilidad de género que se encuentra en las historias de vida de las mujeres que se suicidaron en los municipios del sur de Brasil. Este estudio cualitativo es parte de un proyecto de investigación titulado "¿Es posible prevenir el avance del final? El suicidio de adultos mayores en Brasil y posibilidades del Sector de Salud". Los datos fueron construidos mediante la técnica de la autopsia psicológica, tratando de entender las historias de vida y los factores de riesgo relacionados con el suicidio. Los principales temas presentes en las historias de vida de las mujeres que se suicidaron fueron clasificadas como debilidades de género y el suicidio como una situación límite. Creemos que las normas de género y los conflictos interpersonales, así como problemas económicos que surgen del trabajo y las enfermedades estaban presentes en la vida de estas mujeres

  16. The significance of climate change in the Netherlands. An analysis of historical and future trends (1901-2020) in weather conditions, weather extremes and temperature-related impacts

    Energy Technology Data Exchange (ETDEWEB)

    Visser, H.

    2005-07-01

    A rigorous statistical analysis reveals changes in Dutch climate that are statistically significant over the last century. Annually averaged temperatures have increased by 1.5 about 0.5 degrees Centigrade; the number of summer days has roughly doubled from 14 about 5 to 27 about 9 days; annual precipitation has increased by 120 about 100 mm; and the number of extremely wet days has increased by about 40%, from 19 about 3 to 26 about 3 days. Several other changes in Dutch climate, such as spring temperatures rising more rapidly than winter temperatures, the increase of the coldest temperature in each year by 0.9 degrees Centigrade and the annual maximum day sum of precipitation, turn out to be not (yet) statistically significant. The changes in Dutch climate have already led to several statistically significant impacts. The length of the growing season has increased by nearly a month, and the number of heating-degree days, a measure for the energy needed for the heating of houses and buildings, has decreased by 14 about 5%. Projections of future temperature increase in 2020 based on the statistical analysis closely resemble projections based on climate models: temperatures continue to increase from 10.4 about 0.4 degrees Centigrade in 2003 to 10.7 about 0.6 degrees Centigrade in 2010 and 11.1 about 1.0 degrees Centigrade in 2020. The energy needed for heating of houses and buildings is expected to decrease further. This warming effect is expected to lower projections of future Dutch greenhouse-gas emissions by 3.5 Mton CO2 equivalents, which is relevant in the context of commitments under the Kyoto Protocol. Finally, over the course of the 20th century the chance on an 'Elfstedentocht', an outdoor skating event in the Netherlands, has decreased from once every five years to once every ten years. Even though this impact change is not yet statistically significant, it resides 'on the edge' of significance: within a few years more evidence may

  17. Assessment of extreme hydrological conditions in the Bothnian Bay, Baltic Sea, and the impact of the nuclear power plant ''Hanhikivi-1'' on the local thermal regime

    Energy Technology Data Exchange (ETDEWEB)

    Dvornikov, Anton Y.; Martyanov, Stanislav D.; Ryabchenko, Vladimir A.; Isaev, Alexey V. [Russian Academy of Sciences, St. Petersburg (Russian Federation). P.P. Shirshov Inst. of Oceanology; Eremina, Tatjana R. [Russian State Hydrometeorological Univ., St. Petersburg (Russian Federation); Sein, Dmitry V. [Helmholtz Centre for Polar and Marine Research, Bremerhaven (Germany). Alfred Wegener Inst.

    2017-07-01

    The results of the study aimed to assess the influence of future nuclear power plant ''Hanhikivi-1'' upon the local thermal conditions in the Bothnian Bay in the Baltic Sea are presented. A number of experiments with different numerical models were also carried out in order to estimate the extreme hydro-meteorological conditions in the area of the construction. The numerical experiments were fulfilled both with analytically specified external forcing and with real external forcing for 2 years: a cold year (2010) and a warm year (2014). The study has shown that the extreme values of sea level and water temperature and the characteristics of wind waves and sea ice in the vicinity of the future nuclear power plant can be significant and sometimes catastrophic. Permanent release of heat into the marine environment from an operating nuclear power plant will lead to a strong increase in temperature and the disappearance of ice cover within a 2 km vicinity of the station. These effects should be taken into account when assessing local climate changes in the future.

  18. Using petrographic techniques to evaluate the induced effects of NaCl, extreme climatic conditions, and traffic load on Spanish road surfaces

    Directory of Open Access Journals (Sweden)

    A. P. Pérez-Fortes

    2017-10-01

    Full Text Available The asphalt surface layer is the most exposed to weather and traffic conditions on roads, especially those subjected to winter maintenance. Therefore, a deep knowledge of the mechanisms which can damage this layer is necessary to improve its design, construction and long-term use. With this purpose, two types of asphalt mixtures used on roads from NW Spain were subjected to durability tests (freezing-thaw and thermal-stress with a saturated NaCl solution. After the durability tests, a wheel tracking test was performed on the samples, and the resultant material was analyzed by optical polarized light and fluorescence microscopy. This analysis showed that the binder-aggregate low adhesion was the main responsible of the asphalt mixture damage. This damage was concentrated in the aggregates because the binder acted as an impermeable wall. Consequently, the NaCl solution penetrated and degraded the aggregates quickly and strongly.

  19. Using petrographic techniques to evaluate the induced effects of NaCl, extreme climatic conditions, and traffic load on Spanish road surfaces

    International Nuclear Information System (INIS)

    Pérez-Fortes, A.F.; Varas-Muriel, M.J.; Castiñeiras, P.

    2017-01-01

    The asphalt surface layer is the most exposed to weather and traffic conditions on roads, especially those subjected to winter maintenance. Therefore, a deep knowledge of the mechanisms which can damage this layer is necessary to improve its design, construction and long-term use. With this purpose, two types of asphalt mixtures used on roads from NW Spain were subjected to durability tests (freezing-thaw and thermal-stress) with a saturated NaCl solution. After the durability tests, a wheel tracking test was performed on the samples, and the resultant material was analyzed by optical polarized light and fluorescence microscopy. This analysis showed that the binder-aggregate low adhesion was the main responsible of the asphalt mixture damage. This damage was concentrated in the aggregates because the binder acted as an impermeable wall. Consequently, the NaCl solution penetrated and degraded the aggregates quickly and strongly. [es

  20. A review on ab initio studies of static, transport, and optical properties of polystyrene under extreme conditions for inertial confinement fusion applications

    Science.gov (United States)

    Hu, S. X.; Collins, L. A.; Boehly, T. R.; Ding, Y. H.; Radha, P. B.; Goncharov, V. N.; Karasiev, V. V.; Collins, G. W.; Regan, S. P.; Campbell, E. M.

    2018-05-01

    Polystyrene (CH), commonly known as "plastic," has been one of the widely used ablator materials for capsule designs in inertial confinement fusion (ICF). Knowing its precise properties under high-energy-density conditions is crucial to understanding and designing ICF implosions through radiation-hydrodynamic simulations. For this purpose, systematic ab initio studies on the static, transport, and optical properties of CH, in a wide range of density and temperature conditions (ρ = 0.1 to 100 g/cm3 and T = 103 to 4 × 106 K), have been conducted using quantum molecular dynamics (QMD) simulations based on the density functional theory. We have built several wide-ranging, self-consistent material-properties tables for CH, such as the first-principles equation of state, the QMD-based thermal conductivity (κQMD) and ionization, and the first-principles opacity table. This paper is devoted to providing a review on (1) what results were obtained from these systematic ab initio studies; (2) how these self-consistent results were compared with both traditional plasma-physics models and available experiments; and (3) how these first-principles-based properties of polystyrene affect the predictions of ICF target performance, through both 1-D and 2-D radiation-hydrodynamic simulations. In the warm dense regime, our ab initio results, which can significantly differ from predictions of traditional plasma-physics models, compared favorably with experiments. When incorporated into hydrocodes for ICF simulations, these first-principles material properties of CH have produced significant differences over traditional models in predicting 1-D/2-D target performance of ICF implosions on OMEGA and direct-drive-ignition designs for the National Ignition Facility. Finally, we will discuss the implications of these studies on the current small-margin ICF target designs using a CH ablator.

  1. The greenhouse effect and extreme weather

    International Nuclear Information System (INIS)

    Groenaas, Sigbjoern; Kvamstoe, Nils Gunnar

    2002-01-01

    The article asserts that an anthropogenic global warming is occurring. This greenhouse effect is expected to cause more occurrences of extreme weather. It is extremely difficult, however, to relate specific weather catastrophes to global warming with certainty, since such extreme weather conditions are rare historically. The subject is controversial. The article also discusses the public debate and the risk of floods

  2. Comparison of Distal Limb Warming With Fluidotherapy and Warm Water Immersion for Mild Hypothermia Rewarming.

    Science.gov (United States)

    Kumar, Parveen; McDonald, Gerren K; Chitkara, Radhika; Steinman, Alan M; Gardiner, Phillip F; Giesbrecht, Gordon G

    2015-09-01

    The purpose of the study was to determine the effectiveness of Fluidotherapy rewarming through the distal extremities for mildly hypothermic, vigorously shivering subjects. Fluidotherapy is a dry heat modality in which cellulose particles are suspended by warm air circulation. Seven subjects (2 female) were cooled on 3 occasions in 8˚C water for 60 minutes, or to a core temperature of 35°C. They were then dried and rewarmed in a seated position by 1) shivering only; 2) Fluidotherapy applied to the distal extremities (46 ± 1°C, mean ± SD); or 3) water immersion of the distal extremities (44 ± 1°C). The order of rewarming followed a balanced design. Esophageal temperature, skin temperature, heart rate, oxygen consumption, and heat flux were measured. The warm water produced the highest rewarming rate, 6.1°C·h(-1), 95% CI: 5.3-6.9, compared with Fluidotherapy, 2.2°C·h(-1), 95% CI: 1.4-3.0, and shivering only, 2.0°C·h(-1), 95% CI: 1.2-2.8. The Fluidotherapy and warm water conditions increased skin temperature and inhibited shivering heat production, thus reducing metabolic heat production (166 ± 42 W and 181 ± 45 W, respectively), compared with shivering only (322 ± 142 W). Warm water provided a significantly higher net heat gain (398.0 ± 52 W) than shivering only (288.4 ± 115 W). Fluidotherapy was not as effective as warm water for rewarming mildly hypothermic subjects. Although Fluidotherapy is more portable and technically simpler, it provides a lower rate of rewarming that is similar to shivering only. It does help decrease shivering heat production, lowering energy expenditure and cardiac work, and could be considered in a hospital setting, if convenient. Copyright © 2015 Wilderness Medical Society. Published by Elsevier Inc. All rights reserved.

  3. Developmental Exposure to Mild Variable Stress: Adult ...

    Science.gov (United States)

    In utero exposure to mild variable stress has been reported to influence learning and memory formation in offspring. Our research aims to examine whether nonchemical environmental stressors will exacerbate effects to chemical exposure. This study utilized a varying stress paradigm to simulate human psychosocial stress incurred during and after pregnancy to identify phenotypic learning changes in adult offspring that are potential stress markers. We additionally wanted to compare these behavioral outcomes to rat performance induced by perinatal exposure to manganese (Mn), a neurotoxic environmental element, at 2 or 5 g/l in drinking water throughout gestation and lactation. Pregnant Long Evans rats were exposed to an unpredictable series of mild stressful events which had previously been shown to increase maternal corticosterone levels. Nonchemical stressors were presented from GD 13 through GD 21 and included varying noise, light, housing, and confinement during both sleep and wake cycles. A subgroup of offspring was also exposed to periods of maternal separation. Starting at PND 97 offspring were trained with a trace fear conditioning protocol whereby rats were exposed to a compound cue (light and tone) followed by 30 seconds (trace period) and a mild foot shock (1mA, 0.5 seconds). Five paired training sessions occurred on the first day. The following day, context and cue learning were assessed by measuring motor activity. Preliminary data suggests adu

  4. Extremely Preterm Birth

    Science.gov (United States)

    ... Events Advocacy For Patients About ACOG Extremely Preterm Birth Home For Patients Search FAQs Extremely Preterm Birth ... Spanish FAQ173, June 2016 PDF Format Extremely Preterm Birth Pregnancy When is a baby considered “preterm” or “ ...

  5. Development of mild steel exposure chart for neutron radiography application

    International Nuclear Information System (INIS)

    Hafizal Yazid; Rafhayudi Jamro; Hishamuddin Husain; Muhammad Rawi Mohd Zin; Razali Kassim; Abd Aziz Mohamed; Azali Muhammad

    2004-01-01

    A neutron radiography exposure chart for mild steel was developed to facilitate the determination of exposure time when producing neutron radiographs for any given mild steel thickness. A mild steel sample in the form of step wedge (1-10 mm thick) was exposed to thermal neutron using Direct technique. This technique involves exposing x-ray film-Gadolinium converter housed in one film cassette simultaneously to thermal neutron beam. Gadolinium converters with thickness of 0.025 mm and 0.5 mm were used to observe the effect of converter thickness on radiographic density and exposure time. Collected radiographic density data is then calculated based on manufacturer's film characteristic chart and finally exposure chart for mild steel was plotted. This chart could later be used as a guide for estimating exposure time for any given sample thickness providing other conditions are similar (material, film processing, neutron flux, film density and converter thickness). (Author)

  6. Development of refractory concrete for extreme conditions

    International Nuclear Information System (INIS)

    Pundiene, I; Antonovich, V; Stonys, R; Demidova-Buiziniene, I

    2011-01-01

    Comparative analysis is provided for the properties of medium-cement refractory concrete with microsilica based on mullite filler in relation to different type of deflocculant. The effect of different deflocculants on refractory concrete structure formation, hydration, rheology, strength and heat resistance is discussed. Corrosion resistance test, determined that samples with hybrid deflocculant showed better resistance for slag penetration than samples with only the sodium tripolyphosphate or polycarboxylate ether deflocculant. Moreover, a composition of hybrid deflocculant let to control the rate of the hydration process and to get features of refractory refractory concrete.

  7. Building GSM network in extreme conditions

    Science.gov (United States)

    Mikulec, M.; Voznak, M.; Fajkus, M.; Partila, P.; Tovarek, J.; Chmelikova, Z.

    2015-05-01

    The paper is focused on the building ad-hoc GSM network based on open source software and low-cost hardware. The created Base Transmission Station can be deployed and put into operation in a few minutes in a required area to ensure private communication between connected GSM mobile terminals. The convergence between BTS station and the other networks is possible through IP network. The paper tries to define connection parameters to provide sufficient quality of voice service between the GSM network and IP Multimedia Subsystem. The paper brings practical results of voice call quality measurement between users inside BTS station mobile network and users inside IP Multimedia Subsystem network. The calls are simulated by low-cost embedded solution for speech quality measurement in GSM network. This tool is under development of our laboratory and allows automatic speech quality measurement of any GSM or UMTS mobile network. The Perceptual Evaluation of Speech Quality method is used to get final comparable results. The communication between BTS station and connected networks has to be secured against the interception from the third party. The influence of the securing method for quality of service is presented in detail. Paper, apart from the quality of service measurement section, describes technical requirements for successful interconnection between BTS and IMS networks. The authentication, authorization and accounting methods in roaming between BTS and IMS system are presented too.

  8. Novel Functional Extended Solids at Extreme Conditions

    Science.gov (United States)

    2013-02-01

    15. SUBJECT TERMS 16. SECURITY CLASSIFICATION OF: 17. LIMITATION OF ABSTRACT 18. NUMBER OF PAGES 19a. NAME OF RESPONSIBLE PERSON a...ray Evidences J. Chem. Phys. 134, 044519 (2011). 19. Magnus J. Lipp, Jae-Hyun Klepeis, Bruce Baer, Hyunchae Cynn, William J. Evans, Valentin Iota

  9. Nuclei at extreme conditions. A relativistic study

    Energy Technology Data Exchange (ETDEWEB)

    Afanasjev, Anatoli [Mississippi State Univ., Mississippi State, MS (United States)

    2014-11-14

    The major goals of the current project were further development of covariant density functional theory (CDFT), better understanding of its features, its application to different nuclear structure and nuclear astrophysics phenomena and training of graduate and undergraduate students. The investigations have proceeded in a number of directions which are discussed in detail in the part “Accomplishments” of this report. We have studied the role of isovector and isoscalar proton-neutron pairings in rotating nuclei; based on available experimental data it was concluded that there are no evidences for the existence of isoscalar proton-neutron pairing. Generalized theoretical approach has been developed for pycnonuclear reaction rates in the crust of neutron stars and interior of white dwarfs. Using this approach, extensive database for considerable number of pycnonuclear reactions involving stable and neutron-rich light nuclei has been created; it can be used in future for the study of various nuclear burning phenomena in different environments. Time-odd mean fields and their manifestations in terminating states, non-rotating and rotating nuclei have been studied in the framework of covariant density functional theory. Contrary to non-relativistic density functional theories these fields, which are important for a proper description of nuclear systems with broken time-reversal symmetry, are uniquely defined in the CDFT framework. Hyperdeformed nuclear shapes (with semi-axis ratio 2.5:1 and larger) have been studied in the Z = 40-58 part of nuclear chart. We strongly believe that such shapes could be studied experimentally in the future with full scale GRETA detector.

  10. The Behavior of Matter under Extreme Conditions

    NARCIS (Netherlands)

    Paerels, F.; Méndez, M.; Agueros, M.; Baring, M.; Barret, D.; Bhattacharyya, S.; Cackett, E.; Cottam, J.; Diaz Trigo, M.; Fox, D.; Garcia, M.; Gotthelf, E.; Hermsen, W.; Ho, W.; Hurley, K.; Jonker, P.; Juett, A.; Kaaret, P.; Kargaltsev, O.; Lattimer, J.; Matt, G.; Özel, F.; Pavlov, G.; Rutledge, R.; Smith, R.; Stella, L.; Strohmayer, T.; Tananbaum, H.; Uttley, P.; van Kerkwijk, M.; Weisskopf, M.; Zane, S.

    2009-01-01

    The cores of neutron stars harbor the highest matter densities known to occur in nature, up to several times the densities in atomic nuclei. Similarly, magnetic field strengths can exceed the strongest fields generated in terrestrial laboratories by ten orders of magnitude. Hyperon-dominated matter,

  11. Materials at extreme conditions: ICF targets

    International Nuclear Information System (INIS)

    More, R.M.

    1980-01-01

    Currently two simple theories are heavily used in laser-fusion research: the Thomas-Fermi-Dirac statistical model, and an atomic ionization model based on screened hydrogen like energy levels. Recent improvements in these theories are summarized. We show representation calculations of thermodynamic properties, ionization, x-ray emission rates and fast-ion stopping powers, and give a brief sketch of the major unresolved scientific questions

  12. Numerical modeling of materials under extreme conditions

    CERN Document Server

    Brown, Eric

    2014-01-01

    The book presents twelve state of the art contributions in the field of numerical modeling of materials subjected to large strain, high strain rates, large pressure and high stress triaxialities, organized into two sections. The first part is focused on high strain rate-high pressures such as those occurring in impact dynamics and shock compression related phenomena, dealing with material response identification, advanced modeling incorporating microstructure and damage, stress waves propagation in solids and structures response under impact. The latter part is focused on large strain-low strain rates applications such as those occurring in technological material processing, dealing with microstructure and texture evolution, material response at elevated temperatures, structural behavior under large strain and multi axial state of stress.

  13. Structural Mineral Physics at Extreme Conditions

    Science.gov (United States)

    Chariton, S.; Dubrovinsky, L. S.; Dubrovinskaia, N.

    2017-12-01

    Laser heating techniques in diamond anvil cells (DACs) cover a wide pressure-temperature range - above 300 GPa and up to 5000 K. Recent advantages in on-line laser heating techniques resulted in a significant improvement of reliability of in situ X-ray powder diffraction studies in laser-heated DACs, which have become routine at a number of synchrotron facilities including specialized beam-lines at the 3rd generation synchrotrons. However, until recently, existing DAC laser-heating systems could not be used for structural X-ray diffraction studies aimed at structural refinements, i.e. measuring of the diffraction intensities, and not only at determining of lattice parameters. The reason is that in existing DAC laser-heating facilities the laser beam enters the cell at a fixed angle, and a partial rotation of the DAC, as required in monochromatic structural X-ray diffraction experiments, results in a loss of the target crystal and may be even dangerous if the powerful laser light starts to scatter in arbitrary directions by the diamond anvils. In order to overcome this problem we have develop a portable laser heating system and implement it at different diffraction beam lines. We demonstrate the application of this system for simultaneous high-pressure and high-temperature powder and single crystal diffraction studies using examples of studies of chemical and phase relations in the Fe-O system, transition metals carbonates, and silicate perovskites.

  14. Anaerobic membrane bioreactor under extreme conditions (poster)

    NARCIS (Netherlands)

    Munoz Sierra, J.D.; De Kreuk, M.K.; Spanjers, H.; Van Lier, J.B.

    2013-01-01

    Membrane bioreactors ensure biomass retention by the application of micro or ultrafiltration processes. This allows operation at high sludge concentrations. Previous studies have shown that anaerobic membrane bioreactors is an efficient way to retain specialist microorganisms for treating

  15. QCD under extreme conditions. Inhomogeneous condensation

    Energy Technology Data Exchange (ETDEWEB)

    Heinz, Achim

    2014-10-15

    Almost 40 years after the first publication on the phase diagram of quantum chromodynamics (QCD) big progress has been made but many questions are still open. This work covers several aspects of low-energy QCD and introduces advanced methods to calculate selected parts of the QCD phase diagram. Spontaneous chiral symmetry breaking as well as its restoration is a major aspect of QCD. Two effective models, the Nambu-Jona-Lasinio (NJL) model and the linear σ-model, are widely used to describe the QCD chiral phase transition. We study the large-N{sub c} behavior of the critical temperature T{sub c} for chiral symmetry restoration in the framework of both models. While in the NJL model T{sub c} is independent of N{sub c} (and in agreement with the expected QCD scaling), the scaling behavior in the linear σ-model reads T{sub c} ∝ N{sup 1/2}{sub c}. However, this mismatch can be corrected: phenomenologically motivated temperature-dependent parameters or the extension with the Polyakov-loop renders the scaling in the linear σ-model compatible with the QCD scaling. The requirement that the chiral condensate which is the order parameter of the chiral symmetry is constant in space is too restrictive. Recent studies on inhomogeneous chiral condensation in cold, dense quark matter suggest a rich crystalline structure. These studies feature models with quark degrees of freedom. In this thesis we investigate the formation of the chiral density wave (CDW) in the framework of the so-called extended linear sigma model (eLSM) at high densities and zero temperature. The eLSM is a modern development of the linear σ-model which contains scalar, pseudoscalar, vector, as well as axial-vector mesons, and in addition, a light tetraquark state. The nucleon and its chiral partner are introduced as parity doublets in the mirror assignment. The model describes successfully the vacuum phenomenology and nuclear matter ground-state properties. As a result we find that an inhomogeneous phase in the form of a CDW dominates the high density regime. The formation of a homogeneous nuclear matter ground state depends on the parameters determined in the vacuum. However, even in the case of a homogeneous nuclear matter ground state the onset of the CDW is not higher than 5.04ρ{sub 0}, a density at which the eLSM is still applicable. Motivated by the rich structure that inhomogeneous condensation produces, and in order to study inhomogeneous condensation in a general framework we describe the finite-mode approach. Former limitations of the finite mode approach to 1+1 dimensions and only one condensate are successively overcome. Different error sources are analyzed and strategies to minimize them are outlined. First, the well-known analytic results for 1+1 dimensional models are reproduced in this purely numerical approach. Second, the finite-mode approach shows to be capable to describe up to four inhomogeneous condensates. Finally, the method is applied to the 3+1 dimensional NJL model. The famous inhomogeneous ''island'' as well as the inhomogeneous ''continent'' are reproduced. The continent persists for different constituent quark masses and different numbers of regulators. However, in contrast to previous findings the continent becomes thinner for increasing chemical potential.

  16. NASA Materials Research for Extreme Conditions

    Science.gov (United States)

    Sharpe, R. J.; Wright, M. D.

    2009-01-01

    This Technical Memorandum briefly covers various innovations in materials science and development throughout the course of the American Space program. It details each innovation s discovery and development, explains its significance, and describes the applications of this material either in the time period discovered or today. Topics of research include silazane polymers, solvent-resistant elastomeric polymers (polyurethanes and polyisocyanurates), siloxanes, the Space Shuttle thermal protection system, phenolic-impregnated carbon ablator, and carbon nanotubes. Significance of these developments includes the Space Shuttle, Apollo programs, and the Constellation program.

  17. Statistical Model of Extreme Shear

    DEFF Research Database (Denmark)

    Larsen, Gunner Chr.; Hansen, Kurt Schaldemose

    2004-01-01

    In order to continue cost-optimisation of modern large wind turbines, it is important to continously increase the knowledge on wind field parameters relevant to design loads. This paper presents a general statistical model that offers site-specific prediction of the probability density function...... by a model that, on a statistically consistent basis, describe the most likely spatial shape of an extreme wind shear event. Predictions from the model have been compared with results from an extreme value data analysis, based on a large number of high-sampled full-scale time series measurements...... are consistent, given the inevitabel uncertainties associated with model as well as with the extreme value data analysis. Keywords: Statistical model, extreme wind conditions, statistical analysis, turbulence, wind loading, statistical analysis, turbulence, wind loading, wind shear, wind turbines....

  18. Factors Influencing the Formation of Corrosive Conditions in Puget Sound and the Extreme Conditions Observed During Summer 2015 Associated with the NE Pacific Warm Anomaly (a.k.a. The Blob)

    Science.gov (United States)

    Alin, S. R.; Curry, B.; Newton, J.; Feely, R. A.; Sutton, A.

    2016-02-01

    Puget Sound is a complex glacial estuarine system that receives input from many rivers and streams, in addition to runoff from the urban and agricultural environments surrounding the southern part of the Salish Sea ecosystem. A series of glacial sills restrict estuarine circulation such that intrusions of seawater only occur episodically, resulting in long residence times in some parts of the basin. Through survey cruises and stationary time-series, we have observed the dynamic biogeochemical cycles in various sub-basins of Puget Sound since 2008. Areas of Puget Sound with restricted circulation may experience conditions of high pCO2, low pH, and low aragonite saturation state throughout the year. Historically, the highest pCO2 and lowest pH and aragonite saturation states have been observed in early fall in Hood Canal. Upwelling of dense, nutrient- and CO2-rich but oxygen-poor water along the coast provides the marine source water for Puget Sound's deep waters. We estimate that marine waters entering Puget Sound via the Strait of Juan de Fuca are now corrosive 95% of the time, representing a 26% increase in frequency since the preindustrial era. Both river inputs and intense primary production in surface waters drive remineralization in deep waters of Puget Sound basins, contributing to the formation of corrosive conditions in waters below the productive surface. In addition, we estimate that regionally enhanced atmospheric CO2 content may result in an increase in CO2 uptake in the region. In 2015 many features of the seasonal carbon cycle were accelerated relative to earlier years, as a result of the influence of the NE Pacific warm anomaly. In southern Hood Canal, the surface spring bloom began weeks earlier than usual, and in July, we saw the lowest estimated pH and aragonite saturation values in deep waters observed to date in Washington marine environments, which was about two months earlier than historical seasonal minima in pH and aragonite saturation.

  19. Production of biosurfactant on crude date syrup under saline conditions by entrapped cells of Natrialba sp. strain E21, an extremely halophilic bacterium isolated from a solar saltern (Ain Salah, Algeria).

    Science.gov (United States)

    Kebbouche-Gana, Salima; Gana, Mohamed Lamine; Ferrioune, Imen; Khemili, Souad; Lenchi, Nesrine; Akmouci-Toumi, Sihem; Bouanane-Darenfed, Nabila Amel; Djelali, Nacer-Eddine

    2013-11-01

    A bacterial strain E21 was isolated from a sample of water collected in the salt lake located close to Ain Salah, Algeria. The analysis of 16S rRNA gene sequence had indicated that the strain had 93 % sequence similarity with the genus Natrialba sp. strain E21 (GenBank, FR750525.1) and was considered extremely halophilic. Production of biosurfactant by the strain E21 with free and entrapped cells was investigated using soluble starch in the saline conditions. Biosurfactant synthesis was followed by measuring the surface tension and emulsifying index 9 days under optimal conditions (40 °C, pH 7). Some diffusional limitations in alginate and agar beads affected the kinetics of biosurfactant production when compared to that obtained with free cells culture. The minimum values of surface tension were 27 and 30 mN m(-1) achieved after 9 days with free and immobilized cells, respectively, while the corresponding maximum E24 values were 65.3 and 62.3 %, respectively. The re-use of bacterial cells along with the limited cell losses provided by the immobilized system might lead to significant reduction of the biosurfactant production cost.

  20. Energy and fuel efficient parallel mild hybrids for urban roads

    International Nuclear Information System (INIS)

    Babu, Ajay; Ashok, S.

    2016-01-01

    Highlights: • Energy and fuel savings depend on battery charge variations and the vehicle speed parameters. • Indian urban conditions provide lot of scope for energy and fuel savings in mild hybrids. • Energy saving strategy has lower payback periods than the fuel saving one in mild hybrids. • Sensitivity to parameter variations is the least for energy saving strategy in a mild hybrid. - Abstract: Fuel economy improvements and battery energy savings can promote the adoption of parallel mild hybrids for urban driving conditions. The aim of this study is to establish these benefits through two operating modes: an energy saving mode and a fuel saving mode. The performances of a typical parallel mild hybrid using these modes were analysed over urban driving cycles, in the US, Europe, and India, with a particular focus on the Indian urban conditions. The energy pack available from the proposed energy-saving operating mode, in addition to the energy already available from the conventional mode, was observed to be the highest for the representative urban driving cycle of the US. The extra energy pack available was found to be approximately 21.9 times that available from the conventional mode. By employing the proposed fuel saving operating mode, the fuel economy improvement achievable in New York City was observed to be approximately 22.69% of the fuel economy with the conventional strategy. The energy saving strategy was found to possess the lowest payback periods and highest immunity to variations in various cost parameters.

  1. Performance and biocompatibility of extremely tough alginate/polyacrylamide hydrogels.

    Science.gov (United States)

    Darnell, Max C; Sun, Jeong-Yun; Mehta, Manav; Johnson, Christopher; Arany, Praveen R; Suo, Zhigang; Mooney, David J

    2013-11-01

    Although hydrogels now see widespread use in a host of applications, low fracture toughness and brittleness have limited their more broad use. As a recently described interpenetrating network (IPN) of alginate and polyacrylamide demonstrated a fracture toughness of ≈ 9000 J/m(2), we sought to explore the biocompatibility and maintenance of mechanical properties of these hydrogels in cell culture and in vivo conditions. These hydrogels can sustain a compressive strain of over 90% with minimal loss of Young's Modulus as well as minimal swelling for up to 50 days of soaking in culture conditions. Mouse mesenchymal stem cells exposed to the IPN gel-conditioned media maintain high viability, and although cells exposed to conditioned media demonstrate slight reductions in proliferation and metabolic activity (WST assay), these effects are abrogated in a dose-dependent manner. Implantation of these IPN hydrogels into subcutaneous tissue of rats for 8 weeks led to mild fibrotic encapsulation and minimal inflammatory response. These results suggest the further exploration of extremely tough alginate/PAAM IPN hydrogels as biomaterials. © 2013 Elsevier Ltd. All rights reserved.

  2. Ecosystem responses to extreme natural events: impacts of three sequential hurricanes in fall 1999 on sediment quality and condition of benthic fauna in the Neuse River Estuary, North Carolina.

    Science.gov (United States)

    Balthis, W Leonard; Hyland, Jeffrey L; Bearden, Daniel W

    2006-08-01

    A study was conducted in November 1999 to assess sediment quality and condition of benthic fauna in the Neuse River Estuary (NRE), North Carolina, USA, following the passage of three Atlantic hurricanes during the two months prior. Samples for analysis of macroinfauna (>0.5 mm sieve size), chemical contamination of sediments, and other abiotic environmental variables (salinity, dissolved oxygen, pH, depth, sediment granulometry) were collected at 20 sites from the mouth of the Neuse River at Pamlico Sound to approximately 90 km upstream. Results were compared to those obtained from the same area in July 1998 using similar protocols. Depressed salinity, caused by extreme rainfall and associated high freshwater flow, persisted throughout much of the estuary, which had experienced periods of water-column stratification and hypoxia of underlying waters. Fifteen of the 20 sites, representing 299 km2 (76% of the survey area), also showed signs of benthic stress based on a multi-metric benthic index of biotic integrity (B-IBI). Benthic impacts included reductions in the abundance, diversity, and numbers of species and shifts in taxonomic composition, with a notable increase in dominance of the opportunistic polychaete Mediomastus ambiseta as other former dominant species declined. There was no significant increase in the extent of chemical contamination compared to pre-hurricane conditions. Storm-related reductions in dissolved oxygen and salinity were the more likely causes of the observed benthic impacts, though it was not possible, based on these results, to separate storm effects from seasonal changes in the benthos and annual episodes of summer anoxia and hypoxia.

  3. Extreme environment electronics

    CERN Document Server

    Cressler, John D

    2012-01-01

    Unfriendly to conventional electronic devices, circuits, and systems, extreme environments represent a serious challenge to designers and mission architects. The first truly comprehensive guide to this specialized field, Extreme Environment Electronics explains the essential aspects of designing and using devices, circuits, and electronic systems intended to operate in extreme environments, including across wide temperature ranges and in radiation-intense scenarios such as space. The Definitive Guide to Extreme Environment Electronics Featuring contributions by some of the world's foremost exp

  4. Mild Solutions of Neutral Stochastic Partial Functional Differential Equations

    Directory of Open Access Journals (Sweden)

    T. E. Govindan

    2011-01-01

    Full Text Available This paper studies the existence and uniqueness of a mild solution for a neutral stochastic partial functional differential equation using a local Lipschitz condition. When the neutral term is zero and even in the deterministic special case, the result obtained here appears to be new. An example is included to illustrate the theory.

  5. modelling of responses from orthogonal metal cutting of mild steel

    African Journals Online (AJOL)

    user

    technical sciences which are shaped by local operating conditions. ... Three different tool types namely, HSS, tungsten carbide and carbide ... procedure indicated that a tape rule model Fat Max Blade. Armor 35' ... Carbon, C. 0.30 – 0.59% ... Block is Mild Steel x carbide. Runs. Cutting Speed. Feed Rate. Depth of Cut. 1. 250.

  6. facile, mild and convenient preparation and characterization of some

    African Journals Online (AJOL)

    B. S. Chandravanshi

    salicylaldehyde with synthetic diamines in methanol solution under mild conditions. ... (11 g, 0.19 mol) potassium hydroxide in 30 mL of water and 10 mL hydrazine ... A mixture of glacial acetic acid (100 mL), 5.8 g of p-amino acetanilide, 8 g of ...

  7. Music Enhances Autobiographical Memory in Mild Alzheimer's Disease

    Science.gov (United States)

    El Haj, Mohamad; Postal, Virginie; Allain, Philippe

    2012-01-01

    Studies have shown that the "Four Seasons" music may enhance the autobiographical performance of Alzheimer's disease (AD) patients. We used a repeated measures design in which autobiographical recall of 12 mild AD patients was assessed using a free narrative method under three conditions: (a) in "Silence," (b) after being exposed to the opus "Four…

  8. Temperature extremes in Europe: mechanisms and responses to climatic change

    International Nuclear Information System (INIS)

    Cattiaux, Julien

    2010-01-01

    Europe witnessed a spate of record-breaking warm seasons during the 2000's. As illustrated by the devastating heat-wave of the summer 2003, these episodes induced strong societal and environmental impacts. Such occurrence of exceptional events over a relatively short time period raised up many questionings in the present context of climate change. In particular, can recent temperature extremes be considered as 'previews' of future climate conditions? Do they result from an increasing temperature variability? These questions constitute the main motivations of this thesis. Thus, our work aims to contribute to the understanding of physical mechanisms responsible for seasonal temperature extremes in Europe, in order to anticipate their future statistical characteristics. Involved processes are assessed by both statistical data-analysis of observations and climate projections and regional modeling experiments. First we show that while the inter-annual European temperature variability appears driven by disturbances in the North-Atlantic dynamics, the recent warming is likely to be dissociated with potential circulation changes. This inconsistency climaxes during the exceptionally mild autumn of 2006, whose temperature anomaly is only half explained by the atmospheric flow. Recent warm surface conditions in the North-Atlantic ocean seem to substantially contribute to the European warming in autumn-winter, through the establishment of advective and radiative processes. In spring-summer, since both advection by the westerlies and Atlantic warming are reduced, more local processes appear predominant (e.g. soil moisture, clouds, aerosols). Then the issue of future evolution of the relationship between North-Atlantic dynamics and European temperatures is addressed, based on climate projections of the International Panel on Climate Change. Multi-model analysis, using both flow-analogues and weather regimes methods, show that the inconsistency noticed over recent decades is

  9. Extreme value distributions

    CERN Document Server

    Ahsanullah, Mohammad

    2016-01-01

    The aim of the book is to give a through account of the basic theory of extreme value distributions. The book cover a wide range of materials available to date. The central ideas and results of extreme value distributions are presented. The book rwill be useful o applied statisticians as well statisticians interrested to work in the area of extreme value distributions.vmonograph presents the central ideas and results of extreme value distributions.The monograph gives self-contained of theory and applications of extreme value distributions.

  10. Functional Hubs in Mild Cognitive Impairment

    Science.gov (United States)

    Navas, Adrián; Papo, David; Boccaletti, Stefano; Del-Pozo, F.; Bajo, Ricardo; Maestú, Fernando; Martínez, J. H.; Gil, Pablo; Sendiña-Nadal, Irene; Buldú, Javier M.

    We investigate how hubs of functional brain networks are modified as a result of mild cognitive impairment (MCI), a condition causing a slight but noticeable decline in cognitive abilities, which sometimes precedes the onset of Alzheimer's disease. We used magnetoencephalography (MEG) to investigate the functional brain networks of a group of patients suffering from MCI and a control group of healthy subjects, during the execution of a short-term memory task. Couplings between brain sites were evaluated using synchronization likelihood, from which a network of functional interdependencies was constructed and the centrality, i.e. importance, of their nodes was quantified. The results showed that, with respect to healthy controls, MCI patients were associated with decreases and increases in hub centrality respectively in occipital and central scalp regions, supporting the hypothesis that MCI modifies functional brain network topology, leading to more random structures.

  11. Development of an advanced continuous mild gasification process for the production of coproducts

    Energy Technology Data Exchange (ETDEWEB)

    Merriam, N.W.; Jha, M.C.

    1991-11-01

    This report is a final brief summary of development of a mild-gasification and char conversion process. Morgantown Energy Technology Center developed a concept called mild gasification. In this concept, devolatilization of coal under nonoxidizing and relatively mild temperature and pressure conditions can yield three marketable products: (1) a high-heating-value gas, (2) a high-aromatic coal liquid, and (3) a high-carbon char. The objective of this program is to develop an advanced, continuous, mild-gasification process to produce products that will make the concept economically and environmentally viable. (VC)

  12. Development of an advanced continuous mild gasification process for the production of coproducts. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Merriam, N.W.; Jha, M.C.

    1991-11-01

    This report is a final brief summary of development of a mild-gasification and char conversion process. Morgantown Energy Technology Center developed a concept called mild gasification. In this concept, devolatilization of coal under nonoxidizing and relatively mild temperature and pressure conditions can yield three marketable products: (1) a high-heating-value gas, (2) a high-aromatic coal liquid, and (3) a high-carbon char. The objective of this program is to develop an advanced, continuous, mild-gasification process to produce products that will make the concept economically and environmentally viable. (VC)

  13. Simulation of MILD combustion using Perfectly Stirred Reactor model

    KAUST Repository

    Chen, Z.

    2016-07-06

    A simple model based on a Perfectly Stirred Reactor (PSR) is proposed for moderate or intense low-oxygen dilution (MILD) combustion. The PSR calculation is performed covering the entire flammability range and the tabulated chemistry approach is used with a presumed joint probability density function (PDF). The jet, in hot and diluted coflow experimental set-up under MILD conditions, is simulated using this reactor model for two oxygen dilution levels. The computed results for mean temperature, major and minor species mass fractions are compared with the experimental data and simulation results obtained recently using a multi-environment transported PDF approach. Overall, a good agreement is observed at three different axial locations for these comparisons despite the over-predicted peak value of CO formation. This suggests that MILD combustion can be effectively modelled by the proposed PSR model with lower computational cost.

  14. Prenatal natural history of isolated fetal mild bilateral pyelectasis

    Directory of Open Access Journals (Sweden)

    Gustavo de Paula Pereira

    Full Text Available OBJECTIVE: To analyze the prenatal outcomes in a cohort of fetuses with mild bilateral pyelectasis and determine whether performing serial ultrasounds is a good follow-up strategy. METHODS: A prospective longitudinal study was conducted on 62 fetuses with mild bilateral pyelectasis. Fetal mild bilateral pyelectasis was considered when the renal pelvis measured (in millimeters ≥5.0 to 10.0, ≥7.0 to 10.0, and ≥10.0 to 15 at ≤23 weeks 6 days, 24 to 31 weeks 6 days, and ≥32 weeks, respectively, with no uretero-calyceal dilatation. Ultrasounds were performed every 3 weeks to assess whether the mild bilateral pyelectasis regressed, remained unchanged (Group 1 or progressed (Group 2. RESULTS: Group 1 consisted of 53 fetuses (85.4%, and progression was observed in 9 cases (Group 2, 14.6%. The initial renal pelvis diameter was significantly larger in fetuses with progression (p=0.028. Statistically significant differences in the renal pelvis diameter were also found at weeks 31 and 35 for both kidneys (p<0.05. The cases requiring intrauterine procedures or early delivery were not observed. CONCLUSION: Fetal mild bilateral pyelectasis with no calyceal dilatation is a benign condition that can be managed in the postnatal period. The initial renal pelvis diameter and the diameter in week 31 or 35 were valuable parameters for identifying cases that would eventually need specific postnatal procedures.

  15. Mild renal insufficiency is associated with increased cardiovascular mortality: The Hoorn study

    NARCIS (Netherlands)

    Henry, Ronald M.A.; Kostense, Piet J.; Bos, Griêt; Dekker, Jacqueline M.; Nijpels, Giel; Heine, Robert J.; Bouter, Lex M.; Stehouwer, Coen D.A.

    2002-01-01

    BACKGROUND: Cardiovascular mortality is extremely high in end-stage renal disease. Cardiovascular mortality risk also is increased in selected (high-risk) individuals with mild to moderate impairment of renal function. It is not clear whether a similar association exists in the general population

  16. Consumer preferences for mild cheddar cheese flavors.

    Science.gov (United States)

    Drake, S L; Gerard, P D; Drake, M A

    2008-11-01

    Flavor is an important factor in consumer selection of cheeses. Mild Cheddar cheese is the classification used to describe Cheddar cheese that is not aged extensively and has a "mild" flavor. However, there is no legal definition or age limit for Cheddar cheese to be labeled mild, medium, or sharp, nor are the flavor profiles or flavor expectations of these cheeses specifically defined. The objectives of this study were to document the distinct flavor profiles among commercially labeled mild Cheddar cheeses, and to characterize if consumer preferences existed for specific mild Cheddar cheese flavors or flavor profiles. Flavor descriptive sensory profiles of a representative array of commercial Cheddar cheeses labeled as mild (n= 22) were determined using a trained sensory panel and an established cheese flavor sensory language. Nine representative Cheddar cheeses were selected for consumer testing. Consumers (n= 215) assessed the cheeses for overall liking and other consumer liking attributes. Internal preference mapping, cluster analysis, and discriminant analysis were conducted. Mild Cheddar cheeses were diverse in flavor with many displaying flavors typically associated with more age. Four distinct consumer clusters were identified. The key drivers of liking for mild Cheddar cheese were: color, cooked/milky, whey and brothy flavors, and sour taste. Consumers have distinct flavor and color preferences for mild Cheddar cheese. These results can help manufacturers understand consumer preferences for mild Cheddar cheese.

  17. Direct liquefaction of low-rank coals under mild conditions

    Energy Technology Data Exchange (ETDEWEB)

    Braun, N.; Rinaldi, R. [Max-Planck-Institut fuer Kohlenforschung, Muelheim an der Ruhr (Germany)

    2013-11-01

    Due to decreasing of petroleum reserves, direct coal liquefaction is attracting renewed interest as an alternative process to produce liquid fuels. The combination of hydrogen peroxide and coal is not a new one. In the early 1980, Vasilakos and Clinton described a procedure for desulfurization by leaching coal with solutions of sulphuric acid/H{sub 2}O{sub 2}. But so far, H{sub 2}O{sub 2} has never been ascribed a major role in coal liquefaction. Herein, we describe a novel approach for liquefying low-rank coals using a solution of H{sub 2}O{sub 2} in presence of a soluble non-transition metal catalyst. (orig.)

  18. Extraction of glycogen on mild condition lacks AIG fraction.

    Science.gov (United States)

    Ghafouri, Z; Rasouli, M

    2016-12-01

    Extraction of animal tissues with cold water or perchloric acid yields less glycogen than is obtained with hot-alkaline. Extraction with acid and alkaline gives two fractions, acid soluble (ASG) and insoluble glycogen (AIG). The aim of this work is to examine the hypothesis that not all liver glycogen is extractable by Tris-buffer using current techniques. Rat liver was homogenized with Tris-buffer pH 8.3 and extracted for the glycogen fractions, ASG and AIG. The degree of homogenization was changed to remove all glycogen. The content of glycogen was 47.7 ± 1.2 and 11.6 ± 0.8 mg/g wet liver in the supernatant and pellet of the first extraction respectively. About 24% of total glycogen is lost through the first pellet. Increasing the extent of homogenization from 30 to 180 sec and from 15000 to 20000 rpm followed with 30 sec ultrasonication did not improve the extraction. ASG and AIG constitute about 77% and 23% of the pellet glycogen respectively. Extraction with cold Tris-buffer failed to extract glycogen completely.  Increasing the extent of homogenization followed with ultrasonication also did not improve the extraction. Thus it is necessary to re-examine the previous findings obtained by extraction with cold Tris-buffer.

  19. How extreme is extreme hourly precipitation?

    Science.gov (United States)

    Papalexiou, Simon Michael; Dialynas, Yannis G.; Pappas, Christoforos

    2016-04-01

    The importance of accurate representation of precipitation at fine time scales (e.g., hourly), directly associated with flash flood events, is crucial in hydrological design and prediction. The upper part of a probability distribution, known as the distribution tail, determines the behavior of extreme events. In general, and loosely speaking, tails can be categorized in two families: the subexponential and the hyperexponential family, with the first generating more intense and more frequent extremes compared to the latter. In past studies, the focus has been mainly on daily precipitation, with the Gamma distribution being the most popular model. Here, we investigate the behaviour of tails of hourly precipitation by comparing the upper part of empirical distributions of thousands of records with three general types of tails corresponding to the Pareto, Lognormal, and Weibull distributions. Specifically, we use thousands of hourly rainfall records from all over the USA. The analysis indicates that heavier-tailed distributions describe better the observed hourly rainfall extremes in comparison to lighter tails. Traditional representations of the marginal distribution of hourly rainfall may significantly deviate from observed behaviours of extremes, with direct implications on hydroclimatic variables modelling and engineering design.

  20. Optimization with Extremal Dynamics

    International Nuclear Information System (INIS)

    Boettcher, Stefan; Percus, Allon G.

    2001-01-01

    We explore a new general-purpose heuristic for finding high-quality solutions to hard discrete optimization problems. The method, called extremal optimization, is inspired by self-organized criticality, a concept introduced to describe emergent complexity in physical systems. Extremal optimization successively updates extremely undesirable variables of a single suboptimal solution, assigning them new, random values. Large fluctuations ensue, efficiently exploring many local optima. We use extremal optimization to elucidate the phase transition in the 3-coloring problem, and we provide independent confirmation of previously reported extrapolations for the ground-state energy of ±J spin glasses in d=3 and 4

  1. Effect of air preheat temperature on the MILD combustion of syngas

    International Nuclear Information System (INIS)

    Huang, Mingming; Zhang, Zhedian; Shao, Weiwei; Xiong, Yan; Liu, Yan; Lei, Fulin; Xiao, Yunhan

    2014-01-01

    Highlights: • MILD combustion is achieved with reaction zone covering the entire combustion chamber. • Critical equivalence ratio for the occurrence of MILD combustion is identified. • MILD regime can be established for syngas fuel under air preheating conditions. - Abstract: The effect of air preheat temperature on MILD (Moderate or Intense Low-oxygen Dilution) combustion of coal-derived syngas was examined in parallel jet forward flow combustor. The results were presented on flow field using numerical simulations and on global flame signatures, OH ∗ radicals distribution and exhaust emissions using experiments. The discrete and high speed air/fuel injections into the combustor is necessary for the establishment of MILD conditions, because they cause strong gas recirculation and form large mixing region between the air and fuel jets. The critical equivalence ratio above which MILD combustion occurred was identified. The MILD regime was established for syngas fuel under air preheating conditions with lean operational limit and suppressed NO x and CO emissions. In the MILD combustion regime, the air preheating resulted in higher NO x but lower CO emissions, while the increase of equivalence ratio led to the increase of NO x and the decrease of CO emissions

  2. Asthma in Patients Climbing to High and Extreme Altitudes in the Tibetan Everest Region

    NARCIS (Netherlands)

    Huismans, Henrike K.; Douma, W. Rob; Kerstjens, Huib A. M.; Renkema, Tineke E. J.

    Objectives: The aim of this study was to investigate the behavior of asthma in patients traveling to high and extreme altitudes. Methods: Twenty-four Dutch patients with mild asthma did a trekking at high and extreme altitudes (up to 6410 m = 21030 ft) in the Tibetan Everest region. Asthma symptoms,

  3. Mild mental stress in diabetes

    DEFF Research Database (Denmark)

    Hildebrandt, P; Mehlsen, J; Sestoft, L

    1985-01-01

    A TV-game of tennis of 20 min duration was used to study the influence of mild mental stress on subcutaneous blood-flow (SBF), blood-pressure and heart rate in nine insulin-dependent diabetics and nine healthy subjects. SBF was measured on the thigh by local clearance of xenon-133. Measurements...... were made before, during and after the period of stress. During stress, SBF increased significantly by 26% in the healthy subjects, while SBF remained unchanged in the diabetics. The difference between the two groups was significant (P less than 0.05). Following stress, SBF returned to pre-stress level...... in the healthy subjects, while a significant decrease of 33% was observed in the diabetics. The pre-stress heart rate level was higher and the stress-induced increase in heart rate was less in the diabetics compared with the healthy subjects (P less than 0.05). During the stress a slight--but insignificant...

  4. Understanding mild persistent asthma in children

    DEFF Research Database (Denmark)

    Bisgaard, Hans; Szefler, Stanley J

    2005-01-01

    Limitations in asthma prevalence studies and difficulties in diagnosing pediatric asthma lead to uncertainty over the full extent of mild persistent asthma in children and adolescents. Although recent surveys have reported that the majority of pediatric patients with asthma in the United States...... and Europe have symptoms consistent with mild disease, these surveys have limitations in design. Thus, the true prevalence of mild asthma remains unknown. It is unclear whether children with mild persistent asthma progress to more severe asthma, but the risk of severe asthma exacerbations seems...... to be unrelated to the symptom severity. Clinical studies restricted to pediatric patients with mild asthma are limited, but available data do suggest substantial morbidity of mild persistent asthma in this population and support inhaled corticosteroid intervention. There is a need for further investigation...

  5. Classifying Returns as Extreme

    DEFF Research Database (Denmark)

    Christiansen, Charlotte

    2014-01-01

    I consider extreme returns for the stock and bond markets of 14 EU countries using two classification schemes: One, the univariate classification scheme from the previous literature that classifies extreme returns for each market separately, and two, a novel multivariate classification scheme tha...

  6. Slowing down after a mild traumatic brain injury: a strategy to improve cognitive task performance?

    Science.gov (United States)

    Ozen, Lana J; Fernandes, Myra A

    2012-01-01

    Long-term persistent attention and memory difficulties following a mild traumatic brain injury (TBI) often go undetected on standard neuropsychological tests, despite complaints by mild TBI individuals. We conducted a visual Repetition Detection working memory task to digits, in which we manipulated task difficulty by increasing cognitive load, to identify subtle deficits long after a mild TBI. Twenty-six undergraduate students with a self-report of one mild TBI, which occurred at least 6 months prior, and 31 non-head-injured controls took part in the study. Participants were not informed until study completion that the study's purpose was to examine cognitive changes following a mild TBI, to reduce the influence of "diagnosis threat" on performance. Neuropsychological tasks did not differentiate the groups, though mild TBI participants reported higher state anxiety levels. On our working memory task, the mild TBI group took significantly longer to accurately detect repeated targets on our task, suggesting that slowed information processing is a long-term consequence of mild TBI. Accuracy was comparable in the low-load condition and, unexpectedly, mild TBI performance surpassed that of controls in the high-load condition. Temporal analysis of target identification suggested a strategy difference between groups: mild TBI participants made a significantly greater number of accurate responses following the target's offset, and significantly fewer erroneous distracter responses prior to target onset, compared with controls. Results suggest that long after a mild TBI, high-functioning young adults invoke a strategy of delaying their identification of targets in order to maintain, and facilitate, accuracy on cognitively demanding tasks. © The Author 2011. Published by Oxford University Press. All rights reserved.

  7. Pattern of airway inflammation and remodelling in mild persistent atopic asthma and in mild persistent asthma related to gastroesophageal reflux.

    Science.gov (United States)

    Dal Negro, R W; Guerriero, M; Micheletto, C

    2012-12-01

    The increase of basement membrane thickness (BMAT) represents a structural feature described as commonly characterizing airway remodelling in asthma, even if the non-atopic condition had been investigated only episodically from this point of view. Gastrooesophageal-reflux is a pathological condition which can frequently cause and/or sustain asthma in non-atopic individuals. The aim of the study was to measure BMT; some inflammatory mediators in BAL; cys-leucotrienes (LTE4) in urine; e-NO, and BHR to Methacholine (MCh) in mild atopic and in mild non-atopic, GER-related asthma. After their informed consent, 25 mild atopic (40.9 years +/- 13.1 sd, FEV1 = 95.9% pred. +/- 12.9 sd) and 39 non-atopic, GER-related asthmatics (57.3 years +/- 14.2 ds, FEVY1 = 101.3% pred. +/- 12.2 sd), nonsmoker and of a comparable asthma duration, underwent measurements of basal lung function and bronchial response to MCh (PD20 FEV1); endobronchial biopsies and BAL (in the right middle lobe), and a 24-h gastroesophageal pHmetry. Atopic GER-related asthma showed two distinct patterns of airway inflammation. The eosinophilic contribution to airway inflammation was systematically prevailing in the former group, such as: EOS = 10.7% +/- 13.4 sd vs 2.0% +/- 2.8 sd, p = 0.001; ECP = 344.9 mcg/l +/- 635.9 sd vs 59.2 mcg/l +/- 75.1 sd, p = 0.001. Data from the present study are suggesting that persistent mild atopic and mild GER-related asthma seem to represent two distinct phenotypes of asthma in terms of airway remodelling, and in particular of BMT involvement.

  8. Statistics of Extremes

    KAUST Repository

    Davison, Anthony C.; Huser, Raphaë l

    2015-01-01

    Statistics of extremes concerns inference for rare events. Often the events have never yet been observed, and their probabilities must therefore be estimated by extrapolation of tail models fitted to available data. Because data concerning the event

  9. Analysis of extreme events

    CSIR Research Space (South Africa)

    Khuluse, S

    2009-04-01

    Full Text Available ) determination of the distribution of the damage and (iii) preparation of products that enable prediction of future risk events. The methodology provided by extreme value theory can also be a powerful tool in risk analysis...

  10. Acute lower extremity ischaemia

    African Journals Online (AJOL)

    Acute lower extremity ischaemia. Acute lower limb ischaemia is a surgical emergency. ... is ~1.5 cases per 10 000 persons per year. Acute ischaemia ... Table 2. Clinical features discriminating embolic from thrombotic ALEXI. Clinical features.

  11. Mild processing applied to the inactivation of the main foodborne bacterial pathogens

    DEFF Research Database (Denmark)

    Barba Orellana, Francisco Jose; Koubaa, Mohamed; do Prado-Silva, Leonardo

    2017-01-01

    shelf-lives, pasteurization and commercial sterilization may result in numerous nutritional and sensory changes in foods. To address these disadvantages, mild processing methods (i.e., processing technologies for food preservation that apply mild temperature; ... contaminants have been developed. Scope and approach This review emphasizes the main applications of mild technologies aiming to the inactivation of the four main pathogenic bacteria of relevance for food safety as well as their mechanisms of action. Key findings and conclusions Mild processing technologies...... such as high pressure processing, ultrasounds, pulsed electric fields, UV-light, and atmospheric cold plasma may serve, in some conditions, as useful alternatives to commercial sterilization and pasteurization aiming to destroy foodborne pathogens. Each of these mild technologies has a specific mode...

  12. [How to decide with precision, justice, and equity? Reflections on decision-making in the context of extreme prematurity. Part two: moving toward making the best possible decision: defining conditions for putting decisions into practice].

    Science.gov (United States)

    Azria, E; Tsatsaris, V; Moriette, G; Hirsch, E; Schmitz, T; Cabrol, D; Goffinet, F

    2007-05-01

    Extreme premature child's long-term prognostic is getting better and better known, and if a resuscitation procedure is possible at birth, it won't guarantee survival or a survival free of disability. Incertitude toward individual prognosis and outcome for those children remains considerable. In this field, we are at the frontier of medical knowledge and the answer to the question, "how to decide the ante and postnatal care" is crucial. This work is focused on this problematic of decision-making in the context of extreme prematurity. It attempts to deconstruct this concept and to explicit its stakes. Thus, with the support of the medical sources and of philosophical debates, we tried to build a decision-making procedure that complies with the ethical requirements of medical care, accuracy, justice and equity. This decision-making procedure is primarily concerned with the singularity of each decision situation and it intends to link it closely to the notions of rationality and responsibility.

  13. Extreme weather events and infectious disease outbreaks.

    Science.gov (United States)

    McMichael, Anthony J

    2015-01-01

    Human-driven climatic changes will fundamentally influence patterns of human health, including infectious disease clusters and epidemics following extreme weather events. Extreme weather events are projected to increase further with the advance of human-driven climate change. Both recent and historical experiences indicate that infectious disease outbreaks very often follow extreme weather events, as microbes, vectors and reservoir animal hosts exploit the disrupted social and environmental conditions of extreme weather events. This review article examines infectious disease risks associated with extreme weather events; it draws on recent experiences including Hurricane Katrina in 2005 and the 2010 Pakistan mega-floods, and historical examples from previous centuries of epidemics and 'pestilence' associated with extreme weather disasters and climatic changes. A fuller understanding of climatic change, the precursors and triggers of extreme weather events and health consequences is needed in order to anticipate and respond to the infectious disease risks associated with human-driven climate change. Post-event risks to human health can be constrained, nonetheless, by reducing background rates of persistent infection, preparatory action such as coordinated disease surveillance and vaccination coverage, and strengthened disaster response. In the face of changing climate and weather conditions, it is critically important to think in ecological terms about the determinants of health, disease and death in human populations.

  14. PREDICTION OF THE EXTREMAL SHAPE FACTOR OF SPHEROIDAL PARTICLES

    Directory of Open Access Journals (Sweden)

    Daniel Hlubinka

    2011-05-01

    Full Text Available In the stereological unfolding problem for spheroidal particles the extremal shape factor is predicted. The theory of extreme values has been used to show that extremes of the planar shape factor of particle sections tend to the same limit distribution as extremes of the original shape factor for both the conditional and marginal distribution. Attention is then paid to the extreme shape factor conditioned by the particle size. Normalizing constants are evaluated for a parametric model and the numerical procedure is tested on real data from metallography.

  15. [Injury mechanisms in extreme violence settings].

    Science.gov (United States)

    Arcaute-Velazquez, Fernando Federico; García-Núñez, Luis Manuel; Noyola-Vilallobos, Héctor Faustino; Espinoza-Mercado, Fernando; Rodríguez-Vega, Carlos Eynar

    2016-01-01

    Extreme violence events are consequence of current world-wide economic, political and social conditions. Injury patterns found among victims of extreme violence events are very complex, obeying several high-energy injury mechanisms. In this article, we present the basic concepts of trauma kinematics that regulate the clinical approach to victims of extreme violence events, in the hope that clinicians increase their theoretical armamentarium, and reflecting on obtaining better outcomes. Copyright © 2016. Published by Masson Doyma México S.A.

  16. Test fields cannot destroy extremal black holes

    International Nuclear Information System (INIS)

    Natário, José; Queimada, Leonel; Vicente, Rodrigo

    2016-01-01

    We prove that (possibly charged) test fields satisfying the null energy condition at the event horizon cannot overspin/overcharge extremal Kerr–Newman or Kerr–Newman–anti de Sitter black holes, that is, the weak cosmic censorship conjecture cannot be violated in the test field approximation. The argument relies on black hole thermodynamics (without assuming cosmic censorship), and does not depend on the precise nature of the fields. We also discuss generalizations of this result to other extremal black holes. (paper)

  17. Higher incidence of mild cognitive impairment in familial hypercholesterolemia

    Science.gov (United States)

    Zambón, D.; Quintana, M.; Mata, P.; Alonso, R.; Benavent, J.; Cruz-Sánchez, F.; Gich, J.; Pocoví, M.; Civeira, F.; Capurro, S.; Bachman, D.; Sambamurti, K.; Nicholas, J.; Pappolla, M. A.

    2010-01-01

    Objective Hypercholesterolemia is an early risk factor for Alzheimer’s disease. Low density lipoprotein (LDL) receptors may be involved in this disorder. Our objective was to determine the risk of mild cognitive impairment in a population of patients with heterozygous familial hypercholesterolemia, a condition involving LDL receptors dysfunction and life long hypercholesterolemia. Methods Using a cohort study design, patients with (N=47) meeting inclusion criteria and comparison patients without familial hypercholesterolemia (N=70) were consecutively selected from academic specialty and primary care clinics respectively. All patients were older than 50 years. Those with disorders which could impact cognition, including history of stroke or transient ischemic attacks, were excluded from both groups. Thirteen standardized neuropsychological tests were performed in all subjects. Mutational analysis was performed in patients with familial hypercholesterolemia and brain imaging was obtained in those with familial hypercholesterolemia and mild cognitive impairment. Results Patients with familial hypercholesterolemia showed a very high incidence of mild cognitive impairment compared to those without familial hypercholesterolemia (21.3% vs. 2.9%; p = 0.00). This diagnosis was unrelated to structural pathology or white matter disease. There were significant differences between the familial hypercholesterolemia and the no-familial hypercholesterolemia groups in several cognitive measures, all in the direction of worse performance for familial hypercholesterolemia patients, independent of apoE4 or apoE2 status. Conclusions Because prior studies have shown that older patients with sporadic hypercholesterolemia do not show higher incidence of mild cognitive impairment, the findings presented here suggest that early exposure to elevated cholesterol or LDL receptors dysfunction may be risk factors for mild cognitive impairment. PMID:20193836

  18. Corrosion behavior of duplex polyaniline/epoxy coating on mild steel in 3% NaCl

    Directory of Open Access Journals (Sweden)

    Gvozdenović Milica M.

    2005-01-01

    Full Text Available The corrosion behavior and thermal stability of epoxy coatings electrodeposited on mild steel and on mild steel with electrochemically deposited polyaniline (PANI film were investigated by electrochemical impedance spectroscopy (EIS and thermo gravimetric analysis (TGA. The aim of the paper was to present new findings on the corrosion protection of mild steel by a duplex PANI/-epoxy coating in 3% NaCI solution and to determine the effect of thin PANI film on the protective properties of the coating. PANI film was deposited electrochemically on mild steel from an aqueous solution of 0.5 mol dm"3 sodium benzoate and 0.1 mol dm"3 aniline at a constant current density of 1.5 mA cm"2. Non-pigmented epoxy coatings on mild steel and on mild steel with PANI film were obtained by cathodic electrode position at constant voltage and stirring conditions. The resin concentration in the electrode position bath was 10 wt.% solid dispersion in water at pH 5.7. The applied voltage was 250 V, the temperature 26°C and the deposition time 3 min. It was shown that thin PANI film could be used to modify the surface of mild steel prior to epoxy coating deposition, due to the increased corrosion protection of a duplex PANI/epoxy coating comparing to an epoxy coating on mild steel in 3% NaCl solution.

  19. Extreme Programming: Maestro Style

    Science.gov (United States)

    Norris, Jeffrey; Fox, Jason; Rabe, Kenneth; Shu, I-Hsiang; Powell, Mark

    2009-01-01

    "Extreme Programming: Maestro Style" is the name of a computer programming methodology that has evolved as a custom version of a methodology, called extreme programming that has been practiced in the software industry since the late 1990s. The name of this version reflects its origin in the work of the Maestro team at NASA's Jet Propulsion Laboratory that develops software for Mars exploration missions. Extreme programming is oriented toward agile development of software resting on values of simplicity, communication, testing, and aggressiveness. Extreme programming involves use of methods of rapidly building and disseminating institutional knowledge among members of a computer-programming team to give all the members a shared view that matches the view of the customers for whom the software system is to be developed. Extreme programming includes frequent planning by programmers in collaboration with customers, continually examining and rewriting code in striving for the simplest workable software designs, a system metaphor (basically, an abstraction of the system that provides easy-to-remember software-naming conventions and insight into the architecture of the system), programmers working in pairs, adherence to a set of coding standards, collaboration of customers and programmers, frequent verbal communication, frequent releases of software in small increments of development, repeated testing of the developmental software by both programmers and customers, and continuous interaction between the team and the customers. The environment in which the Maestro team works requires the team to quickly adapt to changing needs of its customers. In addition, the team cannot afford to accept unnecessary development risk. Extreme programming enables the Maestro team to remain agile and provide high-quality software and service to its customers. However, several factors in the Maestro environment have made it necessary to modify some of the conventional extreme

  20. [Definition and clinical characteristics of mild hypertension].

    Science.gov (United States)

    Saruta, Takao

    2008-08-01

    Mild hypertension is defined as blood pressure level of 140-159 mmHg systolic and/or 90-99 mmHg diastolic. The patients with blood pressure level of mild hypertension occupy about 60% of total hypertensive patients in Japan, and most of them are free of subjective symptoms except elevated blood pressure. However, some of the patients with mild hypertension develop cardiovascular events, since thay have occasionally cardiovascular damages on this level of blood pressure and several risk factors of cardiovascular diseases such as diabetes mellitus and hyperlipidemia.

  1. Extremely deformable structures

    CERN Document Server

    2015-01-01

    Recently, a new research stimulus has derived from the observation that soft structures, such as biological systems, but also rubber and gel, may work in a post critical regime, where elastic elements are subject to extreme deformations, though still exhibiting excellent mechanical performances. This is the realm of ‘extreme mechanics’, to which this book is addressed. The possibility of exploiting highly deformable structures opens new and unexpected technological possibilities. In particular, the challenge is the design of deformable and bi-stable mechanisms which can reach superior mechanical performances and can have a strong impact on several high-tech applications, including stretchable electronics, nanotube serpentines, deployable structures for aerospace engineering, cable deployment in the ocean, but also sensors and flexible actuators and vibration absorbers. Readers are introduced to a variety of interrelated topics involving the mechanics of extremely deformable structures, with emphasis on ...

  2. Statistics of Extremes

    KAUST Repository

    Davison, Anthony C.

    2015-04-10

    Statistics of extremes concerns inference for rare events. Often the events have never yet been observed, and their probabilities must therefore be estimated by extrapolation of tail models fitted to available data. Because data concerning the event of interest may be very limited, efficient methods of inference play an important role. This article reviews this domain, emphasizing current research topics. We first sketch the classical theory of extremes for maxima and threshold exceedances of stationary series. We then review multivariate theory, distinguishing asymptotic independence and dependence models, followed by a description of models for spatial and spatiotemporal extreme events. Finally, we discuss inference and describe two applications. Animations illustrate some of the main ideas. © 2015 by Annual Reviews. All rights reserved.

  3. Trans-generational effects of mild heat stress on the life history traits of an aphid parasitoid.

    Science.gov (United States)

    Ismaeil, Ibrahim; Doury, Géraldine; Desouhant, Emmanuel; Dubois, Françoise; Prevost, Geneviève; Couty, Aude

    2013-01-01

    Temperature changes are common in nature and insects are particularly exposed and sensitive to such variations which can be potential stresses, ultimately affecting life history traits and overall fitness. Braconids have been widely used to study the effects of temperature on host-parasitoid interactions and the present work focused on the solitary endoparasitoid Aphidius ervi Haliday (Hymenoptera: Braconidae Aphidiidae), an efficient biological control agent commercially used against aphids such as the potato aphid Macrosiphum euphorbiae Thomas (Sternorrhyncha: Aphididae). Contrary to previous studies using heat shocks at extreme temperatures, we evaluated the effects of mild heat stresses by transferring young parasitoid adults from the constant temperature of 20°C to either a warm (25°C) or hot (28°C) temperature, for either 1 h or 48 h. Such treatments are consistent with situations commonly experienced by parasitoids when moved from their rearing conditions to greenhouses or field conditions. The effects were evaluated both on the heat stressed A. ervi adults (G0) (immediate effects) and on their first generation (G1) progeny (trans-generational effects). G0 wasps' mortality was significantly affected by the temperature in interaction with the duration of the stress. Longevity of G0 wasps surviving the heat stress was negatively affected by the temperature and females lived longer than males. Heat stress applied to A. ervi parents also had consequences on their G1 progeny whose developmental time, rates of mummification and percentage of parasitoid completing total development were negatively affected. Surprisingly, the egg load at emergence of the G1 female progeny was increased when their mothers had been submitted to a mild heat stress of 25°C or 28°C. These results clearly demonstrate trans-generational phenotypic plasticity, showing that adaptation to thermal stresses may be achieved via maternal effects. This study also sheds light on the complexity

  4. Trans-generational effects of mild heat stress on the life history traits of an aphid parasitoid.

    Directory of Open Access Journals (Sweden)

    Ibrahim Ismaeil

    Full Text Available Temperature changes are common in nature and insects are particularly exposed and sensitive to such variations which can be potential stresses, ultimately affecting life history traits and overall fitness. Braconids have been widely used to study the effects of temperature on host-parasitoid interactions and the present work focused on the solitary endoparasitoid Aphidius ervi Haliday (Hymenoptera: Braconidae Aphidiidae, an efficient biological control agent commercially used against aphids such as the potato aphid Macrosiphum euphorbiae Thomas (Sternorrhyncha: Aphididae. Contrary to previous studies using heat shocks at extreme temperatures, we evaluated the effects of mild heat stresses by transferring young parasitoid adults from the constant temperature of 20°C to either a warm (25°C or hot (28°C temperature, for either 1 h or 48 h. Such treatments are consistent with situations commonly experienced by parasitoids when moved from their rearing conditions to greenhouses or field conditions. The effects were evaluated both on the heat stressed A. ervi adults (G0 (immediate effects and on their first generation (G1 progeny (trans-generational effects. G0 wasps' mortality was significantly affected by the temperature in interaction with the duration of the stress. Longevity of G0 wasps surviving the heat stress was negatively affected by the temperature and females lived longer than males. Heat stress applied to A. ervi parents also had consequences on their G1 progeny whose developmental time, rates of mummification and percentage of parasitoid completing total development were negatively affected. Surprisingly, the egg load at emergence of the G1 female progeny was increased when their mothers had been submitted to a mild heat stress of 25°C or 28°C. These results clearly demonstrate trans-generational phenotypic plasticity, showing that adaptation to thermal stresses may be achieved via maternal effects. This study also sheds light on

  5. A mild and efficient procedure for the synthesis of ethers from various alkyl halides

    Directory of Open Access Journals (Sweden)

    Mosstafa Kazemi

    2013-10-01

    Full Text Available A simple, mild and practical procedure has been developed for the synthesis of symmetrical and unsymmetrical ethers by using DMSO, TBAI in the presence of K2CO3. We extended the utility of Potassium carbonate as an efficient base for the preparation of ethers. A wide range of alkyl aryl and dialkyl ethers are synthezied from treatment of aliphatic alcohols and phenols with various alkyl halides in the prescence of efficient base Potassium carbonate. Secondary alkyl halides were easily converted to corresponding ethers in releatively good yields . This is a mild, simple and practical procedure for the preparation of ethers in high yields and suitable times under mild condition.

  6. Evaluation of reduced chemical kinetic mechanisms used for modeling mild combustion for natural gas

    Directory of Open Access Journals (Sweden)

    Hamdi Mohamed

    2009-01-01

    Full Text Available A numerical and parametric study was performed to evaluate the potential of reduced chemistry mechanisms to model natural gas chemistry including NOx chemistry under mild combustion mode. Two reduced mechanisms, 5-step and 9-step, were tested against the GRI-Mech3.0 by comparing key species, such as NOx, CO2 and CO, and gas temperature predictions in idealized reactors codes under mild combustion conditions. It is thus concluded that the 9-step mechanism appears to be a promising reduced mechanism that can be used in multi-dimensional codes for modeling mild combustion of natural gas.

  7. Probable mild Opitz trigonocephaly C syndrome

    African Journals Online (AJOL)

    Rabah M. Shawky

    2011-12-11

    Dec 11, 2011 ... brachycephaly shape to the skull, hypoplastic scrotum and bilateral undescended testes, and mild generalised ... It may occur isolated or syndromic involving other abnor- ..... [12] Sargent C, Burn J, Baraitser M, Pembrey ME.

  8. Postpartum Depression After Mild and Severe Preeclampsia

    NARCIS (Netherlands)

    Hoedjes, Meeke; Berks, Durk; Vogel, Ineke; Franx, Arie; Bangma, Meike; Darlington, Anne-Sophie E.; Visser, Willy; Duvekot, Johannes J.; Habbema, J. Dik F.; Steegers, Eric A. P.; Raat, Hein

    2011-01-01

    Objective: To describe the prevalence of postpartum depressive symptoms after preeclampsia, to assess the extent to which the prevalence of postpartum depressive symptoms differs after mild and severe preeclampsia, and to investigate which factors contribute to such differences. Methods: Women

  9. Thermophysiological adaptations to passive mild heat acclimation

    NARCIS (Netherlands)

    Pallubinsky, H; Schellen, L; Kingma, B R M; Dautzenberg, B; van Baak, M A; van Marken Lichtenbelt, W D

    Passive mild heat acclimation (PMHA) reflects realistic temperature challenges encountered in everyday life. Active heat acclimation, combining heat exposure and exercise, influences several important thermophysiological parameters; for example, it decreases core temperature and enhances heat

  10. Mild TBI Diagnosis and Management Strategies

    Data.gov (United States)

    Department of Veterans Affairs — The Mild Traumatic Brain Injury (TBI) Diagnosis and Management Strategies will assist in the study of TBI issues, such as the Influence of Concussion on Persistent...

  11. Adventure and Extreme Sports.

    Science.gov (United States)

    Gomez, Andrew Thomas; Rao, Ashwin

    2016-03-01

    Adventure and extreme sports often involve unpredictable and inhospitable environments, high velocities, and stunts. These activities vary widely and include sports like BASE jumping, snowboarding, kayaking, and surfing. Increasing interest and participation in adventure and extreme sports warrants understanding by clinicians to facilitate prevention, identification, and treatment of injuries unique to each sport. This article covers alpine skiing and snowboarding, skateboarding, surfing, bungee jumping, BASE jumping, and whitewater sports with emphasis on epidemiology, demographics, general injury mechanisms, specific injuries, chronic injuries, fatality data, and prevention. Overall, most injuries are related to overuse, trauma, and environmental or microbial exposure. Copyright © 2016 Elsevier Inc. All rights reserved.

  12. Extremal graph theory

    CERN Document Server

    Bollobas, Bela

    2004-01-01

    The ever-expanding field of extremal graph theory encompasses a diverse array of problem-solving methods, including applications to economics, computer science, and optimization theory. This volume, based on a series of lectures delivered to graduate students at the University of Cambridge, presents a concise yet comprehensive treatment of extremal graph theory.Unlike most graph theory treatises, this text features complete proofs for almost all of its results. Further insights into theory are provided by the numerous exercises of varying degrees of difficulty that accompany each chapter. A

  13. 3, 4-methylenedioximethamphetamin reverses anxiety induced by chronic mild stress

    Directory of Open Access Journals (Sweden)

    Laura Andrea León A

    2013-01-01

    Full Text Available Here we report the effects of subchronic 3, 4 methylenedioximethamphetamine (MDMA on the elevated plusmaze, a widely used animal model of anxiety. Rats exposed to a mild chronic stress (MCS protocol received intracerebroventricular microinjections of the selective serotonin reuptake inhibitor (SSRI – fluoxetine (2.0 ug/ul or MDMA, (2.0 ug/ul for seven days. On the eighth day rats were tested in the elevated plus-maze. Our results showed that sub chronic MDMA interacted with MCS leading to a decrease in anxiety related behaviors including: percentage of open arms entries (F [2, 26] = 4.00; p = 0.031, time spent in the open arms (F [2, 26] = 3.656; p = 0.040 and time spent in the open arms extremities (F [2, 26] = 5.842; p = 0.008. These results suggest a potential effect of MDMA in the reversion of the emotional significance of aversive stimuli.

  14. Guide to MildSim

    DEFF Research Database (Denmark)

    Christensen, Hanne Rolfdal; Thomassen, Kristina; Kofoed, Jens Peter

    The changes in the wave conditions when approaching the coast are caused by shoaling, refraction, diffraction, and wave breaking [Andersen and Frigaard, 2008]. All these effects are easiest taken into account by using a numerical program such as MILDSIM which accurately computes the mentioned eff...

  15. Probabilistic analysis of extreme wind events

    Energy Technology Data Exchange (ETDEWEB)

    Chaviaropoulos, P.K. [Center for Renewable Energy Sources (CRES), Pikermi Attikis (Greece)

    1997-12-31

    A vital task in wind engineering and meterology is to understand, measure, analyse and forecast extreme wind conditions, due to their significant effects on human activities and installations like buildings, bridges or wind turbines. The latest version of the IEC standard (1996) pays particular attention to the extreme wind events that have to be taken into account when designing or certifying a wind generator. Actually, the extreme wind events within a 50 year period are those which determine the ``static`` design of most of the wind turbine components. The extremes which are important for the safety of wind generators are those associated with the so-called ``survival wind speed``, the extreme operating gusts and the extreme wind direction changes. A probabilistic approach for the analysis of these events is proposed in this paper. Emphasis is put on establishing the relation between extreme values and physically meaningful ``site calibration`` parameters, like probability distribution of the annual wind speed, turbulence intensity and power spectra properties. (Author)

  16. Stellar extreme ultraviolet astronomy

    International Nuclear Information System (INIS)

    Cash, W.C. Jr.

    1978-01-01

    The design, calibration, and launch of a rocket-borne imaging telescope for extreme ultraviolet astronomy are described. The telescope, which employed diamond-turned grazing incidence optics and a ranicon detector, was launched November 19, 1976, from the White Sands Missile Range. The telescope performed well and returned data on several potential stellar sources of extreme ultraviolet radiation. Upper limits ten to twenty times more sensitive than previously available were obtained for the extreme ultraviolet flux from the white dwarf Sirius B. These limits fall a factor of seven below the flux predicted for the star and demonstrate that the temperature of Sirius B is not 32,000 K as previously measured, but is below 30,000 K. The new upper limits also rule out the photosphere of the white dwarf as the source of the recently reported soft x-rays from Sirius. Two other white dwarf stars, Feige 24 and G191-B2B, were observed. Upper limits on the flux at 300 A were interpreted as lower limits on the interstellar hydrogen column densities to these stars. The lower limits indicate interstellar hydrogen densitites of greater than .02 cm -3 . Four nearby stars (Sirius, Procyon, Capella, and Mirzam) were observed in a search for intense low temperature coronae or extended chromospheres. No extreme ultraviolet radiation from these stars was detected, and upper limits to their coronal emisson measures are derived

  17. Extremity x-ray

    Science.gov (United States)

    ... page: //medlineplus.gov/ency/article/003461.htm Extremity x-ray To use the sharing features on this page, ... in the body Risks There is low-level radiation exposure. X-rays are monitored and regulated to provide the ...

  18. Extremity perfusion for sarcoma

    NARCIS (Netherlands)

    Hoekstra, Harald Joan

    2008-01-01

    For more than 50 years, the technique of extremity perfusion has been explored in the limb salvage treatment of local, recurrent, and multifocal sarcomas. The "discovery" of tumor necrosis factor-or. in combination with melphalan was a real breakthrough in the treatment of primarily irresectable

  19. Statistics of Local Extremes

    DEFF Research Database (Denmark)

    Larsen, Gunner Chr.; Bierbooms, W.; Hansen, Kurt Schaldemose

    2003-01-01

    . A theoretical expression for the probability density function associated with local extremes of a stochasticprocess is presented. The expression is basically based on the lower four statistical moments and a bandwidth parameter. The theoretical expression is subsequently verified by comparison with simulated...

  20. [The heart in extreme sports: hyperbaric activity and microgravity].

    Science.gov (United States)

    Berrettini, Umberto; Landolfi, Angelo; Patteri, Giovanna

    2008-10-01

    The study of the cardiovascular and respiratory modifications in extreme environments could be useful for the understanding of the adaptive mechanisms of the body in particular conditions. The knowledge of how different environmental conditions in terms of extreme pressure, temperature and gravity modify the neurovegetative and cardiovascular system could be useful in daily practice for hypobaric and hyperbaric sports.

  1. Preferential radiosensitization of human prostatic carcinoma cells by mild hyperthermia

    International Nuclear Information System (INIS)

    Ryu, Samuel; Brown, Stephen L.; Kim, Sang-Hie; Khil, Mark S.; Kim, Jae Ho

    1996-01-01

    Purpose: Recent cell culture studies by us and others suggest that some human carcinoma cells are more sensitive to heat than are rodent cells following mild hyperthermia. In studying the cellular mechanism of enhanced thermosensitivity of human tumor cells to hyperthermia, prostatic carcinoma cells of human origin were found to be more sensitive to mild hyperthermia than other human cancer cells. The present study was designed to determine the magnitude of radiosensitization of human prostatic carcinoma cells by mild hyperthermia and to examine whether the thermal radiosensitization is related to the intrinsic thermosensitivity of cancer cells. Methods and Materials: Two human prostatic carcinoma cell lines (DU-145 and PC-3) and other carcinoma cells of human origin, in particular, colon (HT-29), breast (MCF-7), lung (A-549), and brain (U-251) were exposed to temperatures of 40-41 deg. C. Single acute dose rate radiation and fractionated radiation were combined with mild hyperthermia to determine thermal radiosensitization. The end point of the study was the colony-forming ability of single-plated cells. Results: DU-145 and PC-3 cells were found to be exceedingly thermosensitive to 41 deg. C for 24 h, relative to other cancer cell lines. Ninety percent of the prostatic cancer cells were killed by a 24 h heat exposure. Prostatic carcinoma cells exposed to a short duration of heating at 41 deg. C for 2 h resulted in a substantial enhancement of radiation-induced cytotoxicity. The thermal enhancement ratios (TERs) of single acute dose radiation following heat treatment 41 deg. C for 2 h were 2.0 in DU-145 cells and 1.4 in PC-3 cells. The TERs of fractionated irradiation combined with continuous heating at 40 deg. C were similarly in the range of 2.1 to 1.4 in prostate carcinoma cells. No significant radiosensitization was observed in MCF-7 and HT-29 cells under the same conditions. Conclusion: The present data suggest that a significant radiosensitization of

  2. Health-related quality of life, emotional and behavioral problems in mild to moderate prematures at (pre-)school age

    NARCIS (Netherlands)

    Ketharanathan, N.; Lee, W.; Mol, A.C. de

    2011-01-01

    BACKGROUND: There is a gap in the knowledge of longterm outcome of mild to moderate prematures compared to the extreme prematures or very low birth weight infants. AIM: Determine health-related quality of life (HRQoL) and prevalence of emotional and behavioral problems in (pre-)school age children

  3. Increased susceptibility of dystrophin-deficient brain to mild hypoxia

    International Nuclear Information System (INIS)

    Wallis, T.; Rae, C.; Bubb, W.A.; Head, S.I.

    2002-01-01

    Full text: Duchenne muscular dystrophy is an X-linked disorder resulting from total absence of the 427 kDa protein dystrophin. Dystrophin is normally expressed in the brain mainly in a neuronal subpopulation: cortical pyramidal cells, hippocampal CA1 neurons and cerebellar Purkinje cells. One suggested role for dystrophin is in colocalising mitochondrial creatine kinase with ADP translocase and ATP synthase in mitochondria. Brain tissue slices in the murine model of Duchenne dystrophy, the mdx mouse, have been shown to be more sensitive to hypoxia than control. In this work, we used 13 C NMR to monitor the metabolic response of mdx cortical brain tissue slices to normoxia (95%O 2 /5% CO 2 ) and mild hypoxia (95%air/5% CO 2 ). Under normoxic conditions, mdx cortical slices displayed increased net flux through the Krebs cycle and glutamate/glutamine cycle, consistent with the proposed GABA A lesion which results in decreased inhibitory input. By contrast, mild hypoxia resulted in a significant increase in the total pool size of lactate and decreased net flux of 13 C from [3- 13 C]pyruvate into glutamate C4, GABA C2 and Ala C2, as well as decreased anaplerotic activity as measured by the ratio of Asp C2: Asp C3 label. Mild hypoxia has a significantly greater effect on brain oxidative metabolism in mdx mice, than in control

  4. CONDICIÓN FÍSICA Y HÁBITOS DE PRÁCTICA FÍSICO-DEPORTIVA DE LOS CAZADORES EXTREMEÑOS [Physical condition and habits of practice exercise of hunters extremeños

    Directory of Open Access Journals (Sweden)

    José Martín Gamonales Puerto

    2016-12-01

    Present study analyses the physical condition and the physical-sportive exercise in a random sample of hunters (n=144 in the Extremadura (Spain. Hunting is recognized as a sportive modality by the Board of the CDS (Spanish High Sports Council. In order to know the physical condition levels in hunters group, were used a selection of Eurofit and AFISAL-INEFC tests for adult. Final results show the relation which exist between physical condition and sociodemographic differences, as well as the influence that hunting can have in a healthy lifestyle. Attending to the results, there are differences in the physical condition according to the age of the individuals. Moreover, it shows a relation between the sociodemographic characteristics of the sample and the additional physical-sportive exercises of the different modalities of hunting.

  5. Mild Primary Hyperparathyroidism: A Literature Review

    Science.gov (United States)

    Applewhite, Megan K.

    2014-01-01

    The biochemical profile of classic primary hyperparathyroidism (pHPT) consists of both elevated calcium and parathyroid hormone levels. The standard of care is parathyroidectomy unless prohibited by medical comorbidities. Because more patients are undergoing routine bone density evaluation and neck imaging studies for other purposes, there is a subset of people identified with a biochemically mild form of the pHPT that expresses itself as either elevated calcium or parathyroid hormone levels. These patients often do not fall into the criteria for operation based on the National Institutes of Health consensus guidelines, and they can present a challenge of diagnosis and management. The purpose of this paper is to review the available literature on mild pHPT in an effort to better characterize this patient population and to determine whether patients benefit from parathyroidectomy. Evidence suggests that there are patients with mild pHPT who have overt symptoms that are found to improve after parathyroidectomy. There is also a group of patients with biochemically mild pHPT who are found to progress to classic pHPT over time; however, it is not predictable which group of patients this will be. Early intervention for this group with mild pHPT may prevent progression of bone, psychiatric, and renal complications, and parathyroidectomy has proven safe in appropriately selected patients at high volume centers. PMID:25063228

  6. Extremes in nature

    CERN Document Server

    Salvadori, Gianfausto; Kottegoda, Nathabandu T

    2007-01-01

    This book is about the theoretical and practical aspects of the statistics of Extreme Events in Nature. Most importantly, this is the first text in which Copulas are introduced and used in Geophysics. Several topics are fully original, and show how standard models and calculations can be improved by exploiting the opportunities offered by Copulas. In addition, new quantities useful for design and risk assessment are introduced.

  7. Rhabdomyosarcoma of the extremity

    International Nuclear Information System (INIS)

    Rao, Bhaskar N

    1997-01-01

    Rhabdomyosarcoma is the most common soft tissue sarcoma accounting for almost 55%. These tumors arise from unsegmented mesoderm or primitive mesenchyma, which have the capacity to differentiate into muscle. Less than 5% occur in the first year of life. Extremity rhabdomyosarcoma are mainly seen in the adolescent years. The most common histologic subtype is the alveolar variant. Other characteristics of extremity rhabdomyosarcoma include a predilection for lymph node metastasis, a high local failure, and a relatively low survival rate. They often present as slow painless masses; however, lesions in the hand and foot often present as painful masses and imaging studies may show invasion of the bone. Initial diagnostic approaches include needle biopsy or incisional biopsy for larger lesions. Excisional biopsy is indicated preferably for lesions less than 2.5 cm. following this in most instances therapy is initiated with multi agent chemotherapy depending upon response, the next modality may be either surgery with intent to cure or radiation therapy. Amputation of an extremity for local control is not considered in most instances. Prognostic factors that have been determined over the years to be of significance by multi variant analysis have included age, tumor size, invasiveness, presence of either nodal or distant metastasis, and complete excision whenever feasible, with supplemental radiation therapy for local control

  8. Investigating Extreme Lifestyles through Mangrove Transcriptomics

    Science.gov (United States)

    Dassanayake, Maheshi

    2009-01-01

    Mangroves represent phylogenetically diverse taxa in tropical coastal terrestrial habitats. They are extremophiles, evolutionarily adapted to tolerate flooding, anoxia, high temperatures, wind, and high and extremely variable salt conditions in typically resource-poor environments. The genetic basis for these adaptations is, however, virtually…

  9. Extreme Maximum Land Surface Temperatures.

    Science.gov (United States)

    Garratt, J. R.

    1992-09-01

    There are numerous reports in the literature of observations of land surface temperatures. Some of these, almost all made in situ, reveal maximum values in the 50°-70°C range, with a few, made in desert regions, near 80°C. Consideration of a simplified form of the surface energy balance equation, utilizing likely upper values of absorbed shortwave flux (1000 W m2) and screen air temperature (55°C), that surface temperatures in the vicinity of 90°-100°C may occur for dry, darkish soils of low thermal conductivity (0.1-0.2 W m1 K1). Numerical simulations confirm this and suggest that temperature gradients in the first few centimeters of soil may reach 0.5°-1°C mm1 under these extreme conditions. The study bears upon the intrinsic interest of identifying extreme maximum temperatures and yields interesting information regarding the comfort zone of animals (including man).

  10. The pathways by which mild hypothermia inhibits neuronal apoptosis following ischemia/reperfusion injury

    Directory of Open Access Journals (Sweden)

    Chun Luo

    2015-01-01

    Full Text Available Several studies have demonstrated that mild hypothermia exhibits a neuroprotective role and it can inhibit endothelial cell apoptosis following ischemia/reperfusion injury by decreasing casp-ase-3 expression. It is hypothesized that mild hypothermia exhibits neuroprotective effects on neurons exposed to ischemia/reperfusion condition produced by oxygen-glucose deprivation. Mild hypothermia significantly reduced the number of apoptotic neurons, decreased the expression of pro-apoptotic protein Bax and increased mitochondrial membrane potential, with the peak of anti-apoptotic effect appearing between 6 and 12 hours after the injury. These findings indicate that mild hypothermia inhibits neuronal apoptosis following ischemia/reperfusion injury by protecting the mitochondria and that the effective time window is 6-12 hours after ischemia/reperfusion injury

  11. Neuropsychological function following mild exposure to pentaborane

    International Nuclear Information System (INIS)

    Hart, R.P.; Silverman, J.J.; Garrettson, L.K.; Schulz, C.; Hamer, R.M.

    1984-01-01

    Neuropsychological tests and self-report personality inventories were administered to 14 workers and rescue squad personnel approximately 2 months following mild exposure to pentaborane, a highly toxic volatile liquid boron hydride. Performance decrements were evident on 5 of 11 neuropsychological tests, including Block Design and measures of sustained attention and recent memory. Neuropsychological deficits were not related to emotional changes reported on the Hopkins Symptom Checklist nor to the presence of CT scan abnormality. These results indicate mild residual brain dysfunction following pentaborane intoxication, including possible dysfunction in subcortical regions mediating memory processes and in cortical areas mediating visuo-spatial abilities

  12. Virtual Reality Training for Upper Extremity in Subacute Stroke (VIRTUES)

    DEFF Research Database (Denmark)

    Brunner, Iris; Skouen, Jan Sture; Hofstad, Håkon

    2017-01-01

    Objective: To compare the effectiveness of upper extremity virtual reality rehabilitation training (VR) to time-matched conventional training (CT) in the subacute phase after stroke. Methods: In this randomized, controlled, single-blind phase III multicenter trial, 120 participants with upper...... extremity motor impairment within 12 weeks after stroke were consecutively included at 5 rehabilitation institutions. Participants were randomized to either VR or CT as an adjunct to standard rehabilitation and stratified according to mild to moderate or severe hand paresis, defined as $20 degrees wrist...... were assessed at baseline, after intervention, and at the 3-month follow-up. Results: Mean time from stroke onset for the VR group was 35 (SD 21) days and for the CT group was 34 (SD 19) days. There were no between-group differences for any of the outcome measures. Improvement of upper extremity motor...

  13. Generic Hurricane Extreme Seas State

    DEFF Research Database (Denmark)

    Wehmeyer, Christof; Skourup, Jesper; Frigaard, Peter

    2012-01-01

    Extreme sea states, which the IEC 61400-3 (2008) standard requires for the ultimate limit state (ULS) analysis of offshore wind turbines are derived to establish the design basis for the conceptual layout of deep water floating offshore wind turbine foundations in hurricane affected areas....... Especially in the initial phase of floating foundation concept development, site specific metocean data are usually not available. As the areas of interest are furthermore not covered by any design standard, in terms of design sea states, generic and in engineering terms applicable environmental background...... data is required for a type specific conceptual design. ULS conditions for different return periods are developed, which can subsequently be applied in siteindependent analysis and conceptual design. Recordings provided by National Oceanic and Atmospheric Administration (NOAA), of hurricanes along...

  14. Increased levels of conditioned fear and avoidance behavior coincide with changes in phosphorylation of the protein kinase B (AKT) within the amygdala in a mouse model of extremes in trait anxiety.

    Science.gov (United States)

    Yen, Yi-Chun; Mauch, Christoph P; Dahlhoff, Maik; Micale, Vincenzo; Bunck, Mirjam; Sartori, Simone B; Singewald, Nicolas; Landgraf, Rainer; Wotjak, Carsten T

    2012-07-01

    Patients diagnosed for anxiety disorders often display faster acquisition and slower extinction of learned fear. To gain further insights into the mechanisms underlying these phenomenona, we studied conditioned fear in mice originating form a bi-directional selective breeding approach, which is based on elevated plus-maze behavior and results in CD1-derived high (HAB), normal (NAB), and low (LAB) anxiety-related behavior mice. HAB mice displayed pronounced cued-conditioned fear compared to NAB/CD1 and LAB mice that coincided with increased phosphorylation of the protein kinase B (AKT) in the basolateral amygdala 45 min after conditioning. No similar changes were observed after non-associative immediate shock presentations. Fear extinction of recent but not older fear memories was preserved. However, HAB mice were more prone to relapse of conditioned fear with the passage of time. HAB mice also displayed higher levels of contextual fear compared to NAB and LAB mice and exaggerated avoidance following step-down avoidance training. Interestingly, HAB mice showed lower and LAB mice higher levels of acoustic startle responses compared to NAB controls. The increase in arousal observed in LAB mice coincided with the general absence of conditioned freezing. Taken together, our results suggest that the genetic predisposition to high anxiety-related behavior may increase the risk of forming traumatic memories, phobic-like fear and avoidance behavior following aversive encounters, with a clear bias towards passive coping styles. In contrast, genetic predisposition to low anxiety-related and high risk-taking behavior seems to be associated with an increase in active coping styles. Our data imply changes in AKT phosphorylation as a therapeutic target for the prevention of exaggerated fear memories. Copyright © 2012 Elsevier Inc. All rights reserved.

  15. Insertion sequences enrichment in extreme Red sea brine pool vent

    KAUST Repository

    Elbehery, Ali H. A.

    2016-12-03

    Mobile genetic elements are major agents of genome diversification and evolution. Limited studies addressed their characteristics, including abundance, and role in extreme habitats. One of the rare natural habitats exposed to multiple-extreme conditions, including high temperature, salinity and concentration of heavy metals, are the Red Sea brine pools. We assessed the abundance and distribution of different mobile genetic elements in four Red Sea brine pools including the world’s largest known multiple-extreme deep-sea environment, the Red Sea Atlantis II Deep. We report a gradient in the abundance of mobile genetic elements, dramatically increasing in the harshest environment of the pool. Additionally, we identified a strong association between the abundance of insertion sequences and extreme conditions, being highest in the harshest and deepest layer of the Red Sea Atlantis II Deep. Our comparative analyses of mobile genetic elements in secluded, extreme and relatively non-extreme environments, suggest that insertion sequences predominantly contribute to polyextremophiles genome plasticity.

  16. Extreme Programming Pocket Guide

    CERN Document Server

    Chromatic

    2003-01-01

    Extreme Programming (XP) is a radical new approach to software development that has been accepted quickly because its core practices--the need for constant testing, programming in pairs, inviting customer input, and the communal ownership of code--resonate with developers everywhere. Although many developers feel that XP is rooted in commonsense, its vastly different approach can bring challenges, frustrations, and constant demands on your patience. Unless you've got unlimited time (and who does these days?), you can't always stop to thumb through hundreds of pages to find the piece of info

  17. Upper extremity golf injuries.

    Science.gov (United States)

    Cohn, Michael A; Lee, Steven K; Strauss, Eric J

    2013-01-01

    Golf is a global sport enjoyed by an estimated 60 million people around the world. Despite the common misconception that the risk of injury during the play of golf is minimal, golfers are subject to a myriad of potential pathologies. While the majority of injuries in golf are attributable to overuse, acute traumatic injuries can also occur. As the body's direct link to the golf club, the upper extremities are especially prone to injury. A thorough appreciation of the risk factors and patterns of injury will afford accurate diagnosis, treatment, and prevention of further injury.

  18. Do we over treat mild hypertension?

    Science.gov (United States)

    Zanchetti, Alberto

    2015-06-01

    The important question whether 'mild' hypertension should or should not be treated by drugs is difficult to answer, because the only randomized controlled trials (RCTs) investigating this question were conducted when the definition of 'mild' hypertension was based on diastolic blood pressure only, whereas the present definition of grade 1 hypertension includes both systolic and diastolic values (SBP/DBP), and the concept of 'mild' hypertension also includes that of low-moderate cardiovascular risk (hypertension only on the basis of expert opinion. However, recent meta-analyses have provided some support to drug treatment intervention in low-moderate risk grade 1 hypertensives and have shown that, when treatment is deferred until organ damage or cardiovascular disease occur, absolute residual risk (events occurring despite treatment) markedly increases. Although evidence favoring therapeutic intervention in mild hypertension is nowadays stronger than expert opinion, meta-analyses are not substitutes for specific RCTs, and the wide BP spans defining grade 1 hypertension as well as the span defining low-moderate risk leave a wide space for individualized or personalized decisions.

  19. The association between asymptomatic and mild neurocognitive ...

    African Journals Online (AJOL)

    2018-04-12

    Apr 12, 2018 ... antiretroviral therapy among people living with human .... larger than 0.05.26 This is as shown below: = +. −. 1. 1 ..... HAND in general, and did not focus on the mild forms of .... Poster exhibition: Sydney – IAS 2007: Abstract no.

  20. Mission Connect Mild TBI Translational Research Consortium

    Science.gov (United States)

    2013-08-01

    and covered with dental acrylic . Isoflurane was discontinued; rats were connected to the trauma device and subjected to a mild 1.0-atm fluid-percussion...thought to play roles in the regulation of extracellular concentrations of water, potassium and other ions, and glutamate and other transmitters and

  1. Learning Strategies for Adolescents with Mild Disabilities

    Science.gov (United States)

    Conderman, Greg; Koman, Kara; Schibelka, Mary; Higgin, Karen; Cooper, Cody; Butler, Jordyn

    2013-01-01

    Learning strategy instruction is an evidence-based practice for teaching adolescents with mild disabilities. However, researchers have not developed strategies for every content area or skill. Therefore, teachers need to be able develop strategies based on the needs of their students. This article reviews the process for developing and teaching…

  2. Mild disintegration of green microalgae and macroalgae

    NARCIS (Netherlands)

    Postma, Richard

    2016-01-01

    An increased worldwide protein demand for food and feed and the necessity to release the water soluble proteins in the first stage of the cascade biorefinery require the development of mild protein extraction technologies. Cell disintegration is the first hurdle and is considered as one of the

  3. Reducing Truancy in Students with Mild Handicaps.

    Science.gov (United States)

    Hess, Albert M.; And Others

    1990-01-01

    Contingency contracting and group counseling were provided to 26 mildly to moderately handicapped middle school students with high rates of truancy. Subjects exhibited attendance gains after treatment; gains were not maintained at followup but attendance rates were still higher than the rates of control students. Measures of academic performance…

  4. SHORT COMMUNICATION CONVENIENT AND MILD SYNTHESIS ...

    African Journals Online (AJOL)

    Preferred Customer

    *Corresponding author. E-mail: naeimi@kashanu.ac.ir. SHORT COMMUNICATION. CONVENIENT AND MILD SYNTHESIS AND CHARACTERISATION OF. SOME NEW SCHIFF BASES. Hossein Naeimi* and Zahra Sadat Nazifi. Department of Organic Chemistry, Faculty of Chemistry, University of Kashan,. Kashan, 87317 ...

  5. Increase of mild disability in Japanese elders: A seven year follow-up cohort study

    Directory of Open Access Journals (Sweden)

    Okochi Jiro

    2005-05-01

    Full Text Available Abstract Background Japan has the highest life expectancy in the world. In a 2002 census government report, 18.5% of Japanese were 65 years old and over and 7.9% were over 75 years old. In this ageing population, the increase in the number of dependent older persons, especially those with mild levels of disability, has had a significant impact on the insurance budget. This study examines the increase of mild disability and its related factors. Methods All community-dwelling residents aged 65 and over and without functional decline (n = 1560, of Omishima town, Japan, were assessed in 1996 using a simple illustrative measure, "the Typology of the Aged with Illustrations" to establish a baseline level of function and were followed annually until 2002. The prevalence and incidence of low to severe disability, and their association with chronic conditions present at the commencement of the study, was analyzed. A polychotomous logistic regression model was constructed to estimate the association of each chronic condition with two levels of disability. Results An increase in mild functional decline was more prevalent than severe functional decline. The accumulation of mild disability was more prominent in women. The major chronic conditions associated with mild disability were chronic arthritis and diabetes in women, and cerebrovascular accident and malignancy in men. Conclusion This study showed a tendency for mild disability prevalence to increase in Japanese elders, and some risk factors were identified. As mild disability increasingly prevalent, these findings will help determine priorities for its prevention in Japanese elders.

  6. Wind simulation for extreme and fatigue loads

    Energy Technology Data Exchange (ETDEWEB)

    Nielsen, M.; Larsen, G.C.; Mann, J.; Ott, S.; Hansen, K.S.; Pedersen, B.J.

    2004-01-01

    Measurements of atmospheric turbulence have been studied and found to deviate from a Gaussian process, in particular regarding the velocity increments over small time steps, where the tails of the pdf are exponential rather than Gaussian. Principles for extreme event counting and the occurrence of cascading events are presented. Empirical extreme statistics agree with Rices exceedence theory, when it is assumed that the velocity and its time derivative are independent. Prediction based on the assumption that the velocity is a Gaussian process underpredicts the rate of occurrence of extreme events by many orders of magnitude, mainly because the measured pdf is non-Gaussian. Methods for simulation of turbulent signals have been developed and their computational efficiency are considered. The methods are applicable for multiple processes with individual spectra and probability distributions. Non-Gaussian processes are simulated by the correlation-distortion method. Non-stationary processes are obtained by Bezier interpolation between a set of stationary simulations with identical random seeds. Simulation of systems with some signals available is enabled by conditional statistics. A versatile method for simulation of extreme events has been developed. This will generate gusts, velocity jumps, extreme velocity shears, and sudden changes of wind direction. Gusts may be prescribed with a specified ensemble average shape, and it is possible to detect the critical gust shape for a given construction. The problem is formulated as the variational problem of finding the most probable adjustment of a standard simulation of a stationary Gaussian process subject to relevant event conditions, which are formulated as linear combination of points in the realization. The method is generalized for multiple correlated series, multiple simultaneous conditions, and 3D fields of all velocity components. Generalization are presented for a single non-Gaussian process subject to relatively

  7. Meteorological Drivers of Extreme Air Pollution Events

    Science.gov (United States)

    Horton, D. E.; Schnell, J.; Callahan, C. W.; Suo, Y.

    2017-12-01

    The accumulation of pollutants in the near-surface atmosphere has been shown to have deleterious consequences for public health, agricultural productivity, and economic vitality. Natural and anthropogenic emissions of ozone and particulate matter can accumulate to hazardous concentrations when atmospheric conditions are favorable, and can reach extreme levels when such conditions persist. Favorable atmospheric conditions for pollutant accumulation include optimal temperatures for photochemical reaction rates, circulation patterns conducive to pollutant advection, and a lack of ventilation, dispersion, and scavenging in the local environment. Given our changing climate system and the dual ingredients of poor air quality - pollutants and the atmospheric conditions favorable to their accumulation - it is important to characterize recent changes in favorable meteorological conditions, and quantify their potential contribution to recent extreme air pollution events. To facilitate our characterization, this study employs the recently updated Schnell et al (2015) 1°×1° gridded observed surface ozone and particulate matter datasets for the period of 1998 to 2015, in conjunction with reanalysis and climate model simulation data. We identify extreme air pollution episodes in the observational record and assess the meteorological factors of primary support at local and synoptic scales. We then assess (i) the contribution of observed meteorological trends (if extant) to the magnitude of the event, (ii) the return interval of the meteorological event in the observational record, simulated historical climate, and simulated pre-industrial climate, as well as (iii) the probability of the observed meteorological trend in historical and pre-industrial climates.

  8. Lower thermal sensation in normothermic and mildly hyperthermic older adults.

    Science.gov (United States)

    Takeda, Ryosuke; Imai, Daiki; Suzuki, Akina; Ota, Akemi; Naghavi, Nooshin; Yamashina, Yoshihiro; Hirasawa, Yoshikazu; Yokoyama, Hisayo; Miyagawa, Toshiaki; Okazaki, Kazunobu

    2016-05-01

    It is important to know how thermal sensation is affected by normal aging under conditions that elevate core body temperature for the prevention of heat-related illness in older people. We assessed whether thermal sensation under conditions of normothermia (NT) and mild hyperthermia (HT) is lowered in older adults. Seventeen younger (23 ±  3 years) and 12 older (71 ±  3 years) healthy men underwent measurements of the cold and warmth detection thresholds ( ± 0.1 °C/s) of their chest and forearm skin, and whole body warmth perception under NT (esophageal temperature, T es, ~36.5 °C) and HT (T es, ~37.3 °C; lower legs immersed in 42 °C water) conditions. Warmth detection threshold at the forearm was increased in older compared with younger participants under both NT (P = 0.006) and HT (P = 0.004) conditions. In contrast, cold detection threshold at the forearm was decreased in older compared with younger participants under NT (P = 0.001) but not HT (P = 0.16). Mild hyperthermia decreased cold detection threshold at forearm in younger participants (P = 0.001) only. There were no effects of age and condition on warmth and cold detection thresholds at chest. Whole body warmth perception increased during HT compared with NT in both groups (both, P perception under NT and HT and skin cold detection thresholds at forearm under NT deteriorated with aging.

  9. Report from a quality assurance program on patients undergoing the MILD procedure.

    Science.gov (United States)

    Durkin, Brian; Romeiser, Jamie; Shroyer, A Laurie W; Schiller, Robin; Bae, Jin; Davis, Raphael P; Peyster, Robert; Benveniste, Helene

    2013-05-01

    To characterize trends in pain and functional outcomes and identify risk factors in patients with lumbar spinal stenosis (LSS) and neurogenic claudication undergoing the "Minimally Invasive Lumbar Decompression" (MILD) procedure. Retrospective observational cohort study. Academic multidisciplinary pain center at Stony Brook Medicine. Patients undergoing the MILD procedure from October 2010 to November 2012. De-identified perioperative, pain and function related data for 50 patients undergoing MILD were extracted from the Center for Pain Management's quality assessment database. Data included numerical rating scale (NRS), symptom severity and physical function (Zurich Claudication Questionnaire), functional status (Oswestry Disability Index [ODI]), pain interference scores (National Institutes of Health Patient-Reported Outcomes Measurement Information System [PROMIS]), and patients' self-reported low back and lower extremity pain distribution. No MILD patient incurred procedure-related complications. Average NRS scores decreased postoperatively and 64.3% of patients reported less pain at 3 months. Clinically meaningful functional ODI improvements of at least 20% from baseline were present in 25% of the patients at 6 months. Preliminary analysis of changes in PROMIS scores at 3 months revealed that pre-MILD "severe" lumbar canal stenosis may be associated with high risk of "no improvement." No such impact was observed for NRS or ODI outcomes. Overall, pain is reduced and functional status improved in LSS patients following the MILD procedure at 3 and 6 months. Given the small sample size, it is not yet possible to identify patient subgroups at risk for "no improvement." Continued follow-up of longer-term outcomes appears warranted to develop evidence-based patient selection criteria. Wiley Periodicals, Inc.

  10. Extreme river flow dependence in Northern Scotland

    Science.gov (United States)

    Villoria, M. Franco; Scott, M.; Hoey, T.; Fischbacher-Smith, D.

    2012-04-01

    Various methods for the spatial analysis of hydrologic data have been developed recently. Here we present results using the conditional probability approach proposed by Keef et al. [Appl. Stat. (2009): 58,601-18] to investigate spatial interdependence in extreme river flows in Scotland. This approach does not require the specification of a correlation function, being mostly suitable for relatively small geographical areas. The work is motivated by the Flood Risk Management Act (Scotland (2009)) which requires maps of flood risk that take account of spatial dependence in extreme river flow. The method is based on two conditional measures of spatial flood risk: firstly the conditional probability PC(p) that a set of sites Y = (Y 1,...,Y d) within a region C of interest exceed a flow threshold Qp at time t (or any lag of t), given that in the specified conditioning site X > Qp; and, secondly the expected number of sites within C that will exceed a flow Qp on average (given that X > Qp). The conditional probabilities are estimated using the conditional distribution of Y |X = x (for large x), which can be modeled using a semi-parametric approach (Heffernan and Tawn [Roy. Statist. Soc. Ser. B (2004): 66,497-546]). Once the model is fitted, pseudo-samples can be generated to estimate functionals of the joint tails of the distribution of (Y,X). Conditional return level plots were directly compared to traditional return level plots thus improving our understanding of the dependence structure of extreme river flow events. Confidence intervals were calculated using block bootstrapping methods (100 replicates). We report results from applying this approach to a set of four rivers (Dulnain, Lossie, Ewe and Ness) in Northern Scotland. These sites were chosen based on data quality, spatial location and catchment characteristics. The river Ness, being the largest (catchment size 1839.1km2) was chosen as the conditioning river. Both the Ewe (441.1km2) and Ness catchments have

  11. inhibition performance of mild ste thiophene ac rmance of mild steel

    African Journals Online (AJOL)

    userpc

    d Industrial Chemistry, Faculty of Physical Science, Bayero University, Kan. P. M. B. 3011 ..... chemical studies on the inhibition potentials of some ... Efficiency of Thiophene Derivatives on. Mild Steel : A QSAR Model. International. Journal.

  12. Base Oil-Extreme Pressure Additive Synergy in Lubricants

    Science.gov (United States)

    Extreme pressure (EP) additives are those containing reactive elements such as sulfur, phosphorus, and chlorine. In lubrication processes that occur under extremely severe conditions (e.g., high pressure and/or slow speed), these elements undergo chemical reactions generating new materials (tribofi...

  13. Investigating NARCCAP Precipitation Extremes via Bivariate Extreme Value Theory (Invited)

    Science.gov (United States)

    Weller, G. B.; Cooley, D. S.; Sain, S. R.; Bukovsky, M. S.; Mearns, L. O.

    2013-12-01

    We introduce methodology from statistical extreme value theory to examine the ability of reanalysis-drive regional climate models to simulate past daily precipitation extremes. Going beyond a comparison of summary statistics such as 20-year return values, we study whether the most extreme precipitation events produced by climate model simulations exhibit correspondence to the most extreme events seen in observational records. The extent of this correspondence is formulated via the statistical concept of tail dependence. We examine several case studies of extreme precipitation events simulated by the six models of the North American Regional Climate Change Assessment Program (NARCCAP) driven by NCEP reanalysis. It is found that the NARCCAP models generally reproduce daily winter precipitation extremes along the Pacific coast quite well; in contrast, simulation of past daily summer precipitation extremes in a central US region is poor. Some differences in the strength of extremal correspondence are seen in the central region between models which employ spectral nudging and those which do not. We demonstrate how these techniques may be used to draw a link between extreme precipitation events and large-scale atmospheric drivers, as well as to downscale extreme precipitation simulated by a future run of a regional climate model. Specifically, we examine potential future changes in the nature of extreme precipitation along the Pacific coast produced by the pineapple express (PE) phenomenon. A link between extreme precipitation events and a "PE Index" derived from North Pacific sea-surface pressure fields is found. This link is used to study PE-influenced extreme precipitation produced by a future-scenario climate model run.

  14. Gene adaptation to extreme environments

    International Nuclear Information System (INIS)

    Marlaire, P.; Rodriguez, V.; Kerner, N.

    2005-01-01

    Full text: This work is oriented to the study of gene adaptation to extreme conditions, such as the hydrothermal system located in Copahue, Neuquen, Argentina. The organisms living there develop under two pressure selection conditions: the high temperature of thermal water and the strong impact of ultraviolet (UV) radiation. Several microorganisms found in this region were isolated and different colonies resistant to UV radiation were selected, a Geobacillus thermoleovorans strain identified through 16S RNA sequence, being the most remarkable. A gene library was prepared out of this strain with UV sensitive bacteria BH200 (uvrA::Tn10). A number of clones were isolated by means of UV selection, the most outstanding being a gene carrier able to codify for the guanosine monophosphate synthetase enzyme (GMPs). The suitability of said enzyme was proved by means of additional assays performed on ght 1 bacteria (guaA26::Tn 10) which lacked the enzyme. A transcript of 1100 pb was detected through Northern Blot. The result was consistent with that obtained for the mapping of the starting transcription site. The cloned GMPs produces an increase in growth speed and a greater biomass in BH200 bacteria. (author)

  15. Thyroid disorders in mild iodine deficiency

    DEFF Research Database (Denmark)

    Laurberg, P; Nøhr, S B; Pedersen, K M

    2000-01-01

    Comparative epidemiologic studies in areas with low and high iodine intake and controlled studies of iodine supplementation have demonstrated that the major consequence of mild-to-moderate iodine deficiency for the health of the population is an extraordinarily high occurrence of hyperthyroidism...... endangered but the consequences of severe iodine deficiency for brain development are grave and a considerable safety margin is advisable. Moreover, a shift toward less malignant types of thyroid cancer and a lower radiation dose to the thyroid in case of nuclear fallout support that mild-to-moderate iodine...... deficiency should be corrected. However, there is evidence that a high iodine intake may be associated with more autoimmune hypothyroidism, and that Graves' disease may manifest at a younger age and be more difficult to treat. Hence, the iodine intake should be brought to a level at which iodine deficiency...

  16. Lower-Extremity Weakness in a Teenager Due to Thyrotoxic Periodic Paralysis.

    Science.gov (United States)

    Thornton, Matthew D

    2017-04-01

    Thyrotoxic hypokalemic paralysis is the hallmark of thyrotoxic periodic paralysis (TPP). TPP is a potentially deadly complication of hyperthyroidism that occurs because of rapid and dramatic intracellular shift of potassium. This transference results in severe hypokalemia and clinically manifests itself as muscle weakness or paralysis. This condition predominantly affects males of Asian descent, and its presentation can range from mild to severe, as seen in our case. We present the case of a 15-year-old Asian-American male who presented to a tertiary-care pediatric emergency department complaining of generalized weakness and flaccid paralysis of his lower extremities. The differential for such a complaint is extremely broad, and the symptoms can result from etiologies arising from the cerebral cortex, the spinal cord, peripheral nerves, the neuromuscular junction, or even the muscles themselves. Our patient was found to have an extremely low serum potassium concentration, as well as an electrocardiogram that revealed a prolonged QT interval and right bundle branch block. The etiology of these abnormalities and the patient's symptoms was found to be undiagnosed and uncontrolled hyperthyroidism from Grave's disease, which resulted in this dramatic presentation of thyrotoxic hypokalemic paralysis. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: This entity is common in Asia but still somewhat rare in the United States and other Western countries. Our case illustrates that careful history taking and a focused diagnostic evaluation, in conjunction with having an awareness of this disease, can help expedite diagnosis and management, as well as avoid unnecessary and potential harmful testing in the emergency department setting. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. A mild form of Proteus syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Hauer, M.P.; Allmann, K.H.; Langer, M. [Abteilung Roentgendiagnostik, Radiologische Universitaetsklinik, Albert-Ludwigs-Universitaet Freiburg (Germany); Uhl, M. [Sektion Kinderradiologie, Albert-Ludwigs-Universitaet (Germany); Darge, K. [Radiologische Universitaetsklinik, Abteilung Kinderradiologie, Universitaet Heidelberg (Germany)

    1998-05-01

    Proteus syndrome is a rare congenital hamartomatous syndrome. We report on the clinical and radiological appearances of a boy in order to illustrate the typical signs which include subcutaneous masses, in mild forms partial gigantism of hands and feet, hemihypertrophy, and bony abnormalities. We discuss how to make the definitive diagnosis on the basis of using a known rating scale, important aspects of differential diagnosis and clinical features, and diagnostic management. (orig.) With 3 figs., 1 tab., 14 refs.

  18. Spectral characteristics of the nearshore waves off Paradip, India during monsoon and extreme events

    Digital Repository Service at National Institute of Oceanography (India)

    Aboobacker, V.M.; Vethamony, P.; Sudheesh, K.; Rupali, S.P.

    and directional wave energy spectra distinctly separate out the wave conditions that prevailed off Paradip in the monsoon, fair weather and extreme weather events during the above period. Frequency-energy spectra during extreme events are single peaked...

  19. Extreme Heat: A Prevention Guide to Promote Your Personal Health and Safety

    Science.gov (United States)

    ... Extreme Heat Older Adults (Aged 65+) Infants and Children Chronic Medical Conditions Low Income Athletes Outdoor Workers Pets Hot Weather Tips Warning Signs and Symptoms FAQs Social Media How to Stay Cool Missouri Cooling Centers Extreme ...

  20. Extreme Hurricane-Generated Waves in Gulf of Mexico

    National Research Council Canada - National Science Library

    Alberto, Carlos; Fernandes, Santos

    2005-01-01

    .... Although WaveWatchIII (WW3) is used by many operational forecasting centers around the world, there is a lack of field studies to evaluate its accuracy in regional applications and under extreme conditions, such as Hurricanes...

  1. Risk assessment of precipitation extremes in northern Xinjiang, China

    Science.gov (United States)

    Yang, Jun; Pei, Ying; Zhang, Yanwei; Ge, Quansheng

    2018-05-01

    This study was conducted using daily precipitation records gathered at 37 meteorological stations in northern Xinjiang, China, from 1961 to 2010. We used the extreme value theory model, generalized extreme value (GEV) and generalized Pareto distribution (GPD), statistical distribution function to fit outputs of precipitation extremes with different return periods to estimate risks of precipitation extremes and diagnose aridity-humidity environmental variation and corresponding spatial patterns in northern Xinjiang. Spatiotemporal patterns of daily maximum precipitation showed that aridity-humidity conditions of northern Xinjiang could be well represented by the return periods of the precipitation data. Indices of daily maximum precipitation were effective in the prediction of floods in the study area. By analyzing future projections of daily maximum precipitation (2, 5, 10, 30, 50, and 100 years), we conclude that the flood risk will gradually increase in northern Xinjiang. GEV extreme value modeling yielded the best results, proving to be extremely valuable. Through example analysis for extreme precipitation models, the GEV statistical model was superior in terms of favorable analog extreme precipitation. The GPD model calculation results reflect annual precipitation. For most of the estimated sites' 2 and 5-year T for precipitation levels, GPD results were slightly greater than GEV results. The study found that extreme precipitation reaching a certain limit value level will cause a flood disaster. Therefore, predicting future extreme precipitation may aid warnings of flood disaster. A suitable policy concerning effective water resource management is thus urgently required.

  2. Mild obstructive sleep apnoea: clinical relevance and approaches to management.

    Science.gov (United States)

    McNicholas, Walter T; Bonsignore, Maria R; Lévy, Patrick; Ryan, Silke

    2016-10-01

    Obstructive sleep apnoea is highly prevalent in the general population worldwide, especially in its mild form. Clinical manifestations correlate poorly with disease severity measured by the apnoea-hypopnoea index (AHI), which complicates diagnosis. Full polysomnography might be more appropriate to assess suspected mild cases because limited ambulatory diagnostic systems are least accurate in mild disease. Treatment options in mild obstructive sleep apnoea include continuous positive airway pressure (CPAP) and oral appliance therapy, in addition to positional therapy and weight reduction when appropriate. The superior efficacy of CPAP in reducing AHI is offset by greater tolerance of oral appliances, especially in mild disease. Although severe obstructive sleep apnoea is associated with adverse health consequences, including cardiometabolic comorbidities, the association with mild disease is unclear, and reports differ regarding the clinical relevance of mild obstructive sleep apnoea. Improved diagnostic techniques and evidence-based approaches to management in mild obstructive sleep apnoea require further research. Copyright © 2016 Elsevier Ltd. All rights reserved.

  3. Mild Cognitive Impairment and Progession to Dementia: New Findings

    Science.gov (United States)

    ... David C. Spencer, MD Steven Karceski, MD Mild cognitive impairment and progression to dementia New findings John C.S. ... exami- nations showed that 534 persons had mild cognitive impairment, or MCI (see About MCI, following sec- tion). ...

  4. Impact of Mild versus Moderate Intensity Aerobic Walking Exercise ...

    African Journals Online (AJOL)

    2014-03-01

    Mar 1, 2014 ... Objective: To compare the effects of mild and moderate intensity treadmill walking exercises on markers of bone ... second group (B) received mild intensity aerobic exercise training. ..... Using functional loading to influence.

  5. Are BALQSOs extreme accretors?

    Science.gov (United States)

    Yuan, M. J.; Wills, B. J.

    2002-12-01

    Broad Absorption Line (BAL) QSOs are QSOs with massive absorbing outflows up to 0.2c. Two hypothesis have been suggested in the past about the nature of BALQSOs: Every QSO might have BAL outflow with some covering factor. BALQSOs are those which happen to have outflow along our line of sight. BALQSOs have intrinsically different physical properties than non-BALQSOs. Based on BALQSO's optical emission properties and a large set of correlations linking many general QSO emission line and continuum properties, it has been suggested that BALQSOs might accrete at near Eddington limit with abundant of fuel supplies. With new BALQSO Hβ region spectroscopic observation conducted at UKIRT and re-analysis of literature data for low and high redshift non-BALQSOs, We confirm that BALQSOs have extreme Fe II and [O III] emission line properties. Using results derived from the latest QSO Hβ region reverberation mapping, we calculated Eddington ratios (˙ {M}/˙ {M}Edd) for our BAL and non-BALQSOs. The Fe II and [O III] strengths are strongly correlated with Eddington ratios. Those correlations link Eddington ratio to a large set of general QSO properties through the Boroson & Green Eigenvector 1. We find that BALQSOs have Eddington ratios close to 1. However, all high redshift, high luminosity QSOs have rather high Eddington ratios. We argue that this is a side effect from selecting the brightest objects. In fact, our high redshift sample might constitute BALQSO's high Eddington ratio orientation parent population.

  6. A note on extreme sets

    Directory of Open Access Journals (Sweden)

    Radosław Cymer

    2017-10-01

    Full Text Available In decomposition theory, extreme sets have been studied extensively due to its connection to perfect matchings in a graph. In this paper, we first define extreme sets with respect to degree-matchings and next investigate some of their properties. In particular, we prove the generalized Decomposition Theorem and give a characterization for the set of all extreme vertices in a graph.

  7. Problem solving verbal strategies in children with mild intellectual disability

    Directory of Open Access Journals (Sweden)

    Gligorović Milica

    2013-01-01

    Full Text Available Problem solving is a process conditioned by the development and application of efficient strategies. The aim of this research is to determine the level of verbal strategic approach to problem solving in children with mild intellectual disability (MID. The sample consists of 93 children with MID, aged between 10 and 14. Intellectual abilities of the examinees are within the defined range for mild intellectual disability (AM=60.45; SD=7.26. The examinees with evident physical, neurological, and emotional disorders were not included in the sample. The closed 20 Questions Test (20Q was used to assess the development and use of verbal strategy, where the examinee is presented with a poster containing 42 different pictures, and instructed to guess the picture selected by the examiner by asking no more than 20 closed questions. Test χ2, and Spearman and Pearson's correlation coefficient were used in statistical analysis. Research results indicate that most children with MID, aged between 10 and 14, use non-efficient strategy in solving the 20 Questions Test. Although strategic approach to problem solving is present in most children (72%, more than half of the examinees (53.5% use an inadequate strategy. Most children with MID have the ability to categorize concepts, however, they do not use it as a strategy in problem solving.

  8. Numerical study of flame structure in the mild combustion regime

    Directory of Open Access Journals (Sweden)

    Mardani Amir

    2015-01-01

    Full Text Available In this paper, turbulent non-premixed CH4+H2 jet flame issuing into a hot and diluted co-flow air is studied numerically. This flame is under condition of the moderate or intense low-oxygen dilution (MILD combustion regime and related to published experimental data. The modelling is carried out using the EDC model to describe turbulence-chemistry interaction. The DRM-22 reduced mechanism and the GRI2.11 full mechanism are used to represent the chemical reactions of H2/methane jet flame. The flame structure for various O2 levels and jet Reynolds numbers are investigated. The results show that the flame entrainment increases by a decrease in O2 concentration at air side or jet Reynolds number. Local extinction is seen in the upstream and close to the fuel injection nozzle at the shear layer. It leads to the higher flame entertainment in MILD regime. The turbulence kinetic energy decay at centre line of jet decreases by an increase in O2 concentration at hot Co-flow. Also, increase in jet Reynolds or O2 level increases the mixing rate and rate of reactions.

  9. Likelihood estimators for multivariate extremes

    KAUST Repository

    Huser, Raphaë l; Davison, Anthony C.; Genton, Marc G.

    2015-01-01

    The main approach to inference for multivariate extremes consists in approximating the joint upper tail of the observations by a parametric family arising in the limit for extreme events. The latter may be expressed in terms of componentwise maxima, high threshold exceedances or point processes, yielding different but related asymptotic characterizations and estimators. The present paper clarifies the connections between the main likelihood estimators, and assesses their practical performance. We investigate their ability to estimate the extremal dependence structure and to predict future extremes, using exact calculations and simulation, in the case of the logistic model.

  10. Likelihood estimators for multivariate extremes

    KAUST Repository

    Huser, Raphaël

    2015-11-17

    The main approach to inference for multivariate extremes consists in approximating the joint upper tail of the observations by a parametric family arising in the limit for extreme events. The latter may be expressed in terms of componentwise maxima, high threshold exceedances or point processes, yielding different but related asymptotic characterizations and estimators. The present paper clarifies the connections between the main likelihood estimators, and assesses their practical performance. We investigate their ability to estimate the extremal dependence structure and to predict future extremes, using exact calculations and simulation, in the case of the logistic model.

  11. Effects of a Mindfulness-Based Smoking Cessation Program for an Adult with Mild Intellectual Disability

    Science.gov (United States)

    Singh, Nirbhay N.; Lancioni, Giulio E.; Winton, Alan S. W.; Singh, Ashvind N. A.; Singh, Judy; Singh, Angela D. A.

    2011-01-01

    Smoking is a major risk factor for a number of health conditions and many smokers find it difficult to quit smoking without specific interventions. We developed and used a mindfulness-based smoking cessation program with a 31-year-old man with mild intellectual disabilities who had been a smoker for 17 years. The mindfulness-based smoking…

  12. Reminiscence and adaptation to critical life events in older adults with mild to moderate depressive symptoms

    NARCIS (Netherlands)

    Korte, J.; Bohlmeijer, Ernst Thomas; Westerhof, Gerben Johan; Pot, Anne Margriet

    2011-01-01

    Objectives: The role of reminiscence as a way of adapting to critical life events and chronic medical conditions was investigated in older adults with mild to moderate depressive symptoms. Reminiscence is the (non)volitional act or process of recollecting memories of one's self in the past. Method:

  13. People with mild to moderate intellectual disability talking about their diabetes and how they manage.

    NARCIS (Netherlands)

    Cardol, M.; Rijken, M.; Schrojenstein Lantman-de Valk, H. van

    2012-01-01

    Background: The prevalence of diabetes is relatively high in people with intellectual disability (ID). However, little is known about how people with ID experience having diabetes and how they manage the condition. Method: Seventeen people with mild to moderate ID who have diabetes were interviewed.

  14. Mild Hydroprocessing with Dispersed Catalyst of Highly Asphaltenic Pitch

    Science.gov (United States)

    Isquierdo, Fernanda

    Asphaltene are known to have diverse negative impacts on heavy oil extraction and hydroprocessing. This research then, explores the optimal conditions to convert asphaltenes into lighter material using mild conditions of pressure and temperature, and investigates changes in asphaltene structure during hydroprocessing. Feedstock and products were characterized by Simulated Distillation, Microdeasphalting, Sulfur content, X-ray diffraction, X-ray photoelectron spectroscopy, and Nuclear magnetic resonance spectroscopy. Solid catalysts were analyzed by Themogravimetric analysis, X-ray diffraction, and Dynamic light scattering. Based on the results obtained from X-ray diffraction and Nuclear magnetic resonance spectroscopy analysis a mechanism for the asphaltene hydroprocessing at mild conditions is proposed in which the alky peripheric portion from the original asphaltenes is partially removed during the reaction. The consequence of that process being an increase in the stacking of the aromatics sheets in the remaining asphaltenes. Also, this study investigates different for ultradispersed catalyst compositions, where CoWS, CoMoS, NiWS, FeWS, NiMo/NaHFeSi 2O6 and NaHFeSi2O6 showed a high asphaltene conversion as determined by asphaltene microdeasphalting, FeMoS and NaHFeSi 2O6 presented a high Vacuum Residue as determined by distillation (SIMDIST) analysis conversion, and in terms of sulfur removal CoMoS gave the higher conversion. In addition, all the catalyst tested showed a coke production lower than 1%. Finally, a kinetic study for the pitch hydroprocessing using CoMoS as catalysts gave a global activation energy of 97.3 kJ/mol.

  15. Further outlooks: extremely uncomfortable; Die weiteren Aussichten: extrem ungemuetlich

    Energy Technology Data Exchange (ETDEWEB)

    Resenhoeft, T.

    2006-07-01

    Climate is changing extremely in the last decades. Scientists dealing with extreme weather, should not only stare at computer simulations. They have also to turn towards psyche, seriously personal experiences, knowing statistics, relativise supposed sensational reports and last not least collecting more data. (GL)

  16. Comparison of the quick mild cognitive impairment (Qmci) screen and the SMMSE in screening for mild cognitive impairment.

    LENUS (Irish Health Repository)

    O'Caoimh, Rónán

    2012-09-01

    differentiating mild cognitive impairment (MCI) from normal cognition (NC) is difficult. The AB Cognitive Screen (ABCS) 135, sensitive in differentiating MCI from dementia, was modified to improve sensitivity and specificity, producing the quick mild cognitive impairment (Qmci) screen.

  17. Writing Impairments in Japanese Patients with Mild Cognitive Impairment and with Mild Alzheimer's Disease

    Directory of Open Access Journals (Sweden)

    Atsuko Hayashi

    2015-09-01

    Full Text Available Background/Aims: We investigated writing abilities in patients with the amnestic type of mild cognitive impairment (aMCI and mild Alzheimer's disease (AD. To examine the earliest changes in writing function, we used writing tests for both words and sentences with different types of Japanese characters (Hiragana, Katakana, and Kanji. Methods: A total of 25 aMCI patients, 38 AD patients, and 22 healthy controls performed writing to dictation for Kana and Kanji words, copied Kanji words, and wrote in response to a picture story task. Analysis of variance was used to test the subject group effects on the scores in the above writing tasks. Results: For the written Kanji words, the mild AD group performed worse than the aMCI group and the controls, but there was no difference between the aMCI group and the controls. For the picture story writing task, the mild AD and aMCI groups performed worse than the controls, but the difference between the AD and the aMCI groups was not significant. Conclusions: The mild AD group showed defects in writing Kanji characters, and the aMCI group showed impairments in narrative writing. Our study suggests that narrative writing, which demands complex integration of multiple cognitive functions, can be used to detect the subtle writing deficits in aMCI patients.

  18. Writing Impairments in Japanese Patients with Mild Cognitive Impairment and with Mild Alzheimer's Disease.

    Science.gov (United States)

    Hayashi, Atsuko; Nomura, Hiroshi; Mochizuki, Ruriko; Ohnuma, Ayumu; Kimpara, Teiko; Suzuki, Kyoko; Mori, Etsuro

    2015-01-01

    We investigated writing abilities in patients with the amnestic type of mild cognitive impairment (aMCI) and mild Alzheimer's disease (AD). To examine the earliest changes in writing function, we used writing tests for both words and sentences with different types of Japanese characters (Hiragana, Katakana, and Kanji). A total of 25 aMCI patients, 38 AD patients, and 22 healthy controls performed writing to dictation for Kana and Kanji words, copied Kanji words, and wrote in response to a picture story task. Analysis of variance was used to test the subject group effects on the scores in the above writing tasks. For the written Kanji words, the mild AD group performed worse than the aMCI group and the controls, but there was no difference between the aMCI group and the controls. For the picture story writing task, the mild AD and aMCI groups performed worse than the controls, but the difference between the AD and the aMCI groups was not significant. The mild AD group showed defects in writing Kanji characters, and the aMCI group showed impairments in narrative writing. Our study suggests that narrative writing, which demands complex integration of multiple cognitive functions, can be used to detect the subtle writing deficits in aMCI patients.

  19. Modeling Spatial Dependence of Rainfall Extremes Across Multiple Durations

    Science.gov (United States)

    Le, Phuong Dong; Leonard, Michael; Westra, Seth

    2018-03-01

    Determining the probability of a flood event in a catchment given that another flood has occurred in a nearby catchment is useful in the design of infrastructure such as road networks that have multiple river crossings. These conditional flood probabilities can be estimated by calculating conditional probabilities of extreme rainfall and then transforming rainfall to runoff through a hydrologic model. Each catchment's hydrological response times are unlikely to be the same, so in order to estimate these conditional probabilities one must consider the dependence of extreme rainfall both across space and across critical storm durations. To represent these types of dependence, this study proposes a new approach for combining extreme rainfall across different durations within a spatial extreme value model using max-stable process theory. This is achieved in a stepwise manner. The first step defines a set of common parameters for the marginal distributions across multiple durations. The parameters are then spatially interpolated to develop a spatial field. Storm-level dependence is represented through the max-stable process for rainfall extremes across different durations. The dependence model shows a reasonable fit between the observed pairwise extremal coefficients and the theoretical pairwise extremal coefficient function across all durations. The study demonstrates how the approach can be applied to develop conditional maps of the return period and return level across different durations.

  20. Changes in right ventricular function assessed by echocardiography in dog models of mild RV pressure overload.

    Science.gov (United States)

    Morita, Tomoya; Nakamura, Kensuke; Osuga, Tatsuyuki; Yokoyama, Nozomu; Morishita, Keitaro; Sasaki, Noboru; Ohta, Hiroshi; Takiguchi, Mitsuyoshi

    2017-07-01

    The assessment of hemodynamic change by echocardiography is clinically useful in patients with pulmonary hypertension. Recently, mild elevation of the mean pulmonary arterial pressure (PAP) has been shown to be associated with increased mortality. However, changes in the echocardiographic indices of right ventricular (RV) function are still unknown. The objective of this study was to validate the relationship between echocardiographic indices of RV function and right heart catheterization variables under a mild RV pressure overload condition. Echocardiography and right heart catheterization were performed in dog models of mild RV pressure overload induced by thromboxane A 2 analog (U46619) (n=7). The mean PAP was mildly increased (19.3±1.1 mm Hg), and the cardiac index was decreased. Most echocardiographic indices of RV function were significantly impaired even under a mild RV pressure overload condition. Multivariate analysis revealed that the RV free wall longitudinal strain (RVLS), standard deviation of the time-to-peak longitudinal strain of RV six segments (RV-SD) by speckle-tracking echocardiography, and Tei index were independent echocardiographic predictors of the mean PAP (free wall RVLS, β=-0.60, P<.001; RV-SD, β=0.40, P=.011), pulmonary vascular resistance (free wall RVLS, β=-0.39, P=.020; RV-SD, β=0.47, P=.0086; Tei index, β=0.34, P=.047), and cardiac index (Tei index, β=-0.65, P<.001). Free wall RVLS, RV-SD, and Tei index are useful for assessing the hemodynamic change under a mild RV pressure overload condition. © 2017, Wiley Periodicals, Inc.