WorldWideScience

Sample records for extreme weight control

  1. Controlling for the use of extreme weights in bank efficiency assessments during the financial crisis

    DEFF Research Database (Denmark)

    Asmild, Mette; Zhu, Minyan

    2016-01-01

    the financial crisis, we illustrate the impact of the proposed weight restrictions in two different efficiency models; one related to banks’ funding mix and one related to their asset mix. The results show that using a more balanced set of weights tend to reduce the estimated efficiency scores more for those...... banks which were bailed out during the crisis, which confirms the potential bias within standard DEA that does not control for extreme weights applied by highly risky banks. We discuss the use of the proposed method as a regulatory tool to constrain discretion when complying with regulatory capital...... benchmarks such as the Basel regulatory capital ratios....

  2. Extreme Weight-Control Behaviors and Suicide Risk among High School Students

    Science.gov (United States)

    Johnson, Emily R.; Weiler, Robert M.; Barnett, Tracey E.; Pealer, Lisa N.

    2016-01-01

    Background: Suicide is the third leading cause of death for people ages 15-19. Research has established an association across numerous risk factors and suicide, including depression, substance abuse, bullying victimization, and feelings of alienation. However, the connection between disordered eating as manifested in extreme weight-control…

  3. Extreme Weight-Control Behaviors and Suicide Risk among High School Students

    Science.gov (United States)

    Johnson, Emily R.; Weiler, Robert M.; Barnett, Tracey E.; Pealer, Lisa N.

    2016-01-01

    Background: Suicide is the third leading cause of death for people ages 15-19. Research has established an association across numerous risk factors and suicide, including depression, substance abuse, bullying victimization, and feelings of alienation. However, the connection between disordered eating as manifested in extreme weight-control…

  4. Weight Control

    Science.gov (United States)

    ... obese. Achieving a healthy weight can help you control your cholesterol, blood pressure and blood sugar. It ... use more calories than you eat. A weight-control strategy might include Choosing low-fat, low-calorie ...

  5. Risk Factors for Adopting Extreme Weight-Control Behaviors among Public School Adolescents in Salvador, Brazil: A Case-Control Study.

    Science.gov (United States)

    de Santana, Mônica Leila Portela; Assis, Ana Marlúcia Oliveira; Silva, Rita de Cássia Ribeiro; Raich, Rosa María; Machado, Maria Ester Pereira da Conceição; Pinto, Elizabete de Jesus; de Moraes, Lia Terezinha Lana Pimenta; Ribeiro, Hugo da Costa

    2016-01-01

    This study identifies the risk factors for extreme weight-control behaviors among adolescents in public school in Salvador, northeastern Brazil. A case-control study nested to a cross-sectional study, including 252 adolescents of both sexes, age between 11 to 17 years, with 84 cases and 168 age-matched controls was conducted. The variable outcome is represented by extreme weight-control behaviors, integrated by following the variables: self-induced vomiting and the use of laxatives, diuretics, or diet pills. Covariables included body image dissatisfaction, dieting, prolonged fasting, and self-perception of body weight. The study also investigated the demographic and anthropometric variables and economic conditions of the students' families. Conditional logistic regression was used to identify risk factors for the adoption of extreme weight-control behaviors among adolescents. Among the adolescents investigated, the conditional logistic regression explained 22% the occurrence of extreme weight-control behaviors and showed that these behaviors were positively associated to overweight (odds ratio [OR] = 3.61; 95% confidence interval [CI], 1.42-9.17), body image dissatisfaction (OR = 3.87; 95% CI, 1.75-8.54), and the adoption of a restrictive diet (OR = 2.83; 95% CI, 1.16-6.91). The results of this study suggest that among adolescents, overweight, body image dissatisfaction, and restrictive diet are important risk factors to adoption of extreme weight-control behaviors.

  6. Controlling for the use of extreme weights in bank efficiency assessments during the financial crisis

    DEFF Research Database (Denmark)

    Asmild, Mette; Zhu, Minyan

    2016-01-01

    the financial crisis, we illustrate the impact of the proposed weight restrictions in two different efficiency models; one related to banks’ funding mix and one related to their asset mix. The results show that using a more balanced set of weights tend to reduce the estimated efficiency scores more for those...

  7. Development of body weight support gait training system using pneumatic Mckibben actuators -control of lower extremity orthosis.

    Science.gov (United States)

    Mat Dzahir, M A; Nobutomo, T; Yamamoto, S I

    2013-01-01

    Recently, robot assisted therapy devices are increasingly used for spinal cord injury (SCI) rehabilitation in assisting handicapped patients to regain their impaired movements. Assistive robotic systems may not be able to cure or fully compensate impairments, but it should be able to assist certain impaired functions and ease movements. In this study, the control system of lower extremity orthosis for the body weight support gait training system which implements pneumatic artificial muscle (PAM) is proposed. The hip and knee joint angles of the gait orthosis system are controlled based on the PAM coordinates information from the simulation. This information provides the contraction data for the mono- and bi-articular PAMs that are arranged as posterior and anterior actuators to simulate the human walking motion. The proposed control system estimates the actuators' contraction as a function of hip and knee joint angles. Based on the contraction model obtained, input pressures for each actuators are measured. The control system are performed at different gait cycles and two PMA settings for the mono- and bi-articular actuators are evaluated in this research. The results showed that the system was able to achieve the maximum muscle moment at the joints, and able to perform the heel contact movement. This explained that the antagonistic mono- and bi-articular actuators worked effectively.

  8. Frequent Use of Fresh Frozen Plasma Is a Risk Factor for Venous Thrombosis in Extremely Low Birth Weight Infants: A Matched Case-control Study

    Directory of Open Access Journals (Sweden)

    Maruyama,Hidehiko

    2012-02-01

    Full Text Available Percutaneously inserted central catheters (PICCs are often used in neonatal medicine. Venous thrombosis (VT is one of the complications associated with PICC use. According to some reports, fresh frozen plasma (FFP may be a risk factor for VT. The purpose of this study was to determine whether FFP use is associated with VT in extremely low birth weight infants (ELBWIs. We performed a matched case-control study on risk factors for VT in ELBWIs born over a period of 5 years in the neonatal intensive care unit of a tertiary hospital. Controls were infants from the unit matched for gestational age and birth weight. We performed univariate analyses and created receiver operating characteristic (ROC curves for the cut-off values of continuous parameters such as FFP. We also conducted multivariate conditional logistic regression analysis and calculated adjusted odds ratios and their 95% confidence intervals. Thirteen VT cases and 34 matched controls were examined. Using an ROC curve, FFP by day 5>50mL/kg was selected as the cut-off value. In multivariate conditional logistic regression analysis, FFP by day 5>50mL/kg exhibited an adjusted odds ratio of 5.88 (95% confidence interval:1.12-41.81, p=0.036. FFP by day 5>50mL/kg may be a risk factor for VT in ELBWIs.

  9. Lm Extremal Polynomials Associated with Generalized Jacobi Weights

    Institute of Scientific and Technical Information of China (English)

    Ying-guang Shi

    2003-01-01

    Asymptotic estimations of the Christoffel type functions for Lm extremal polynomials with an even integer m associated with generalized Jacobi weights are established. Also, asymptotic behavior of the zeros of the Lm extremal polynomials and the Cotes numbers of the corresponding Turan quadrature formula is given.

  10. Effect factors of extremely unhealthy weight control behaviors among college students%大学生极不健康减肥行为影响因素研究

    Institute of Scientific and Technical Information of China (English)

    方长松; 王庆生; 郝加虎; 黄朝辉; 苏普玉; 庞培; 张家祥; 张婉婉

    2011-01-01

    目的 了解安庆、巢湖两地大学生自我体像与实际体型的符合程度,探讨极不健康减肥行为的影响因素.方法 采取整群抽样方法,抽取安庆、巢湖两地两所大学的学生,采用进行现场调查.统计分析方法包括卡方检验、多因素Logistic回归分析.结果 大学生体型超重或肥胖检出率为5.2%(143/2757),23.0%的女生和12.8%的男生认为自己超重或肥胖,大学生自我体像构成性别差异有统计学意义(χ2=183.85,P<0.001).极不健康减肥行为发生的影响因素有BMI分组、自我体像、性别、家庭居住地、性格.多因素Logistic回归模型结果显示,女生自我体像、自评相貌与极不健康减肥行为之间存在着统计学关联,而男生自我体像、自评相貌与极不健康减肥行为之间关联无统计学意义.结论 青少年学生未能正确评价自己体重,盲目减肥和漠视体重的行为同时存在,极不健康减肥行为在大学生中存在性别差异,女生的自我体像、自评相貌与极不健康减肥行为之间存在着统计学关联.%Aim To understand the coincidence between actual body weight status and self-body image, and to explore the effect factors of extremely unhealthy weight control behaviors. Methods Two universities were selected using cluster sampling method in Anqing City and Chaohu City. Information regarding extremely unhealthy weight control behaviors was collected by self-administered questionnaire.Data were analyzed using Pearson Chi-square and multivariate Logistic regression. Results The prevalence of overeight and obesity was 5.2% (143/2757), but 23.0% of girls and 12.8% boys assessed themselves overeight and obesity, with a significant difference in gender about self-body image(x2 = 183.85,P < 0. 001). The demographic characteristics which influenced extremely unhealthy control behaviors were BMI, self-body image, gender, residence and temperament. The result of the model of

  11. Effect factors of extremely unhealthy weight control behaviors among college students%后腹腔镜上半肾输尿管切除术治疗成人重复肾

    Institute of Scientific and Technical Information of China (English)

    李光远; 于德新; 方卫华; 张志强; 叶楠; 程宗三

    2011-01-01

    Aim To understand the coincidence between actual body weight status and self-body image, and to explore the effect factors of extremely unhealthy weight control behaviors. Methods Two universities were selected using duster sampling method in Anqing City and Chaohu City. Information regarding extremely unhealthy weight control behaviors was collected by self-administered questionnaire.Data were analyzed using Pearson Chi-square and multivariate Logistic regression. Results The prevalence of overweight and obesity was 5.2% (143/2757), but 23.0% of girls and 12.8% boys assessed themselves overweight and obesity, with a significant difference in gender about self-body image(x2 183.85,P < 0. 001). The demographic characteristics which influenced extremely unhealthy control behaviors were BMI, self-body image, gender, residence and temperament. The result of the model of multivariate Logistic regression revealed that self-body image and self-assessment appearance was significantly associated with extremely unhealthy weight control behaviors among girls, but that was not significantly associated with extremely unhealthy weight control behaviors among boys. Conclusion Young students can not correctly assess their own body weight, and the behaviors of blind weight loss and ignoring weight coexist in the research. This study also suggests that self-body image and self-assessment appearance is significantly associated with extremely unhealthy weight control behaviors among girls.%目的 探讨后腹腔镜上半肾输尿管切除术治疗成人重复肾的方法和疗效.方法 回顾分析2008年2月~2010年6月应用后腹腔镜上半肾输尿管切除术治疗12例成人重复肾患者的临床资料.男3例,女9例.年龄18~42岁,平均26岁.观察手术时间、术中出血量、术后早期恢复情况、术中术后并发症、随访下位肾功能及手术疗效.结果 12例手术均成功,手术时间85~175 min,平均125 min,术中出血量20~45 ml

  12. Weight-Control Information Network

    Science.gov (United States)

    ... of resources . Alternate Language URL Weight-control Information Network (WIN) Page Content The Weight-control Information Network ( ... and Digestive and Kidney Diseases, Health Information Center, Telephone: 1-800-860-8747 Contact the NIDDK Health ...

  13. EXTREMAL CONTROL FOR PHOTOVOLTAIC PANELS

    Directory of Open Access Journals (Sweden)

    Genevieve DAPHIN TANGUY

    2016-11-01

    Full Text Available In this paper a methodology for extremal control of photovoltaic panels has been designed through the use of an embedded polynomial controller using robust approaches and algorithms. Also, a framework for testing solar trackers in a hard ware in the loop (HIL configuration has been established. Efficient gradient based optimization methods were put in place in order to determine the parameters of the employed photovoltaic panel, as well as for computing the Maximum Power Point (MPP. Further a numerical RST controller has been computed in order to allow the panel to follow the movement of the sun to obtain a maximum energetic efficiency. A robustness analysis and correction procedure has been done on the RST polynomial algorithm. The hardware in the loop configuration allows for the development of a test and development platform which can be used for bringing improvements to the current design and also test different control approaches. For this, a microcontroller based solution was chosen. The achieved performances of the closed loop photovoltaic panel (PP system are validated in simulation using the MATLAB / SIMULINK environment and the WinPim & WinReg dedicated software. As it will be seen further in this paper, the extremal control of this design resides in a sequential set of computations used for obtaining the new Maximum Power Point at each change in the system.

  14. Body image and extreme attitudes toward weight in Brazilian schoolchildren (PeNSE 2012

    Directory of Open Access Journals (Sweden)

    Rafael Moreira Claro

    2014-01-01

    Full Text Available INTRODUCTION: Adolescence is a period characterized by changes such as accelerated physical growth and sexual development. Besides having to deal with these changes, adolescents are faced with beauty standards and extreme valorization of physical appearance. OBJECTIVE: This article aims to describe body image and the practice of extreme attitudes regarding weight in Brazilian students. METHODS: Data from the National Survey of School Health (PeNSE 2012 were used in this study. PeNSE 2012 has a representative sample of students in the 9th grade of elementary school in public and private schools across the country. A self-administered questionnaire on body image, practice of extreme measures in relation to weight and sociodemographic data was used. Body image and the practice of extreme attitudes were described for the total sample and according to gender. Poisson regression analyzes were used to identify differences in the practices of extreme attitudes between the different types of body image. RESULTS: More than 38% of the adolescents did not consider their body image as normal. Over 15% of the students referred to carry out extreme weight control practices, combining practices to loose and gain weight. Adolescents who considered themselves fat presented frequency of extreme practices for weight loss 92% higher than that shown by individuals who considered themselves normal. Similarly, adolescents who considered themselves thin presented frequency of extreme attitudes to gain weight (9.7% higher than that shown by students who considered themselves normal (5.6%. CONCLUSIONS: The high frequency of extreme weight control practices among Brazilian adolescents is alarming and should be subject of measures in health and education fields.

  15. Autonomic Functioning in Young Adults Born at Extremely Low Birth Weight

    OpenAIRE

    Karen J. Mathewson PhD; Ryan J. Van Lieshout MD, PhD; Saroj Saigal MD; Katherine M. Morrison MD; Michael H. Boyle PhD; Louis A. Schmidt PhD

    2015-01-01

    Autonomic functioning is altered in infants born at extremely low birth weight (ELBW; 2500 g). HF in the smallest-born ELBW participants was significantly lower than in NBW controls. In both groups, greater birth weight was associated with higher HF. Among ELBW survivors, lower birth weight predicted faster heart rate and higher DBP, but neither heart rate nor DBP appeared to be well-coordinated with baroreflex activity (LF), the principal mechanism for short-term blood pressure regulation. A...

  16. Weight control (image)

    Science.gov (United States)

    Weight lifting builds muscle, which increases overall body strength, tone, and balance. Muscles also burn calories more efficiently than fat and other body tissues. So even at rest the more muscle tissue a person has the more calories a person is ...

  17. Financial incentives and weight control.

    Science.gov (United States)

    Jeffery, Robert W

    2012-11-01

    This paper reviews research studies evaluating the use of financial incentives to promote weight control conducted between 1972 and 2010. It provides an overview of behavioral theories pertaining to incentives and describes empirical studies evaluating specific aspects of incentives. Research on financial incentives and weight control has a history spanning more than 30 years. Early studies were guided by operant learning concepts from Psychology, while more recent studies have relied on economic theory. Both theoretical orientations argue that providing financial rewards for losing weight should motivate people to engage in behaviors that produce weight loss. Empirical research has strongly supported this idea. However, results vary widely due to differences in incentive size and schedule, as well as contextual factors. Thus, many important questions about the use of incentives have not yet been clearly answered. Weight-maintenance studies using financial incentives are particularly sparse, so that their long-term efficacy and thus, value in addressing the public health problem of obesity is unclear. Major obstacles to sustained applications of incentive in weight control are funding sources and acceptance by those who might benefit.

  18. Life expectancies and outcomes in extremely low birth weight neonates

    Directory of Open Access Journals (Sweden)

    Nayeri F, Amini E, Shariat M, Mansoori B

    2008-07-01

    Full Text Available "n Background: Much has changed in neonatal care for extremely low birth weight (ELBW; birth weight <1000g infants over the recent years in Iran, resulting in an increase in their survival rate. We determined neonatal survival and short-term morbidity rates among ELBW infants, and the correlation of these factors with mortality risk. "n"nMethods: All single live-born ELBW babies delivered at Vali-e-Asr Hospital over a four-year period were identified. Data that were prospectively collected included: maternal age, prenatal and perinatal complications, antenatal steroid use, birth weight, gestational age, route of delivery, sex, need for resuscitation, APGAR score, need for mechanical  ventilation, and complications including respiratory distress syndrome (RDS, sepsis, jaundice, intraventricular  hemorrhage (IVH, necrotizing entrocolitis (NEC metabolic and hematologic and cardiac disorders. Information was statistically analyzed and a probability value of <0.05 was considered significant. "n"nResults: A total of 93 neonates were included in the study. The survival rate in the delivery room was 36.6%. The lowest birth weight was 400g, with a mean birth weight of 850.43(±136.48g, and the lowest gestational age was 22 weeks. The mean gestational period was 28.31(±2.77 weeks. The most frequent complication after birth was RDS(69.89% and the least frequent was NEC (6.4%. Short and normal gestation was observed in 44.08% and 48.4% of the neonates, respectively. There was a significant relationship between neonatal mortality and the need for resuscitation after birth, RDS and need for a respirator (p<0.05. "n"nFurthermore, there was significant increase in mortality among neonates with gestational age <30 weeks, birth weight under 750g and lack of steroids before birth (p<0.05. "n"nConclusions: To enhance perinatal and neonatal care and decrease the rate of preterm labor, improved standard resuscitation and increased administration of antenatal

  19. Patterns of Weight Control Behavior among 15 year old Girls

    Science.gov (United States)

    Balantekin, Katherine N.; Birch, Leann L.; Savage, Jennifer S.

    2015-01-01

    Objective The objectives were to identify and predict patterns of weight control behavior in 15 year old (yo) girls and to examine weight control group differences in energy intake. Method Subjects included 166 girls assessed every 2 years (ys) from age 5 to 15. Latent class analysis was used to identify patterns of weight control behaviors. Antecedent variables (e.g. inhibitory control at 7ys), and concurrent variables (e.g. BMI and dietary intake at 15ys) were included as predictors. Assessments were a combination of survey, interview, and laboratory measures. Results LCA identified four classes of weight control behaviors, Non-dieters (26%), and three dieting groups: Lifestyle (16%), Dieters (43%), and Extreme Dieters (17%). Levels of restraint, weight concerns, and dieting frequency increased across groups, from Non-dieters to Extreme Dieters. BMI at 5ys and inhibitory control at 7ys predicted weight control group at 15ys; e.g. with every one-point decrease in inhibitory control, girls were twice as likely to be Extreme Dieters than Non-dieters. Girls in the Extreme Dieters group were mostly classified as under-reporters, and had the lowest self-reported intake, but ate significantly more in the laboratory. Discussion Among 15yo girls, “dieting” includes a range of both healthy and unhealthy behaviors. Risk factors for membership in a weight control groups are present as early as 5ys. Patterns of intake in the laboratory support the view that lower reported energy intake by Extreme Dieters is likely due under-reporting as an intent to decrease intake, not actual decreased intake. PMID:26284953

  20. Postnatal transitional weight loss and adverse outcomes in extremely premature neonates

    Directory of Open Access Journals (Sweden)

    Rita P. Verma

    2017-03-01

    Full Text Available The early postnatal weight loss (EPWL is highly variable in the extremely low birth weight infants (birth weight <1000 g, ELBW. It is reported to be unassociated with adverse outcomes within a range of 3- 21% of birth weight. Its wide range might have contributed to this lack of association. The aim of our paper is to study the effects of maximum EPWL, graded as low, medium and large on clinical outcomes in ELBW infants. In a retrospective cohort observational study EPWL was measured as maximum weight loss from birth weight (MWL in ELBW infants and grouped as low (5-12% moderate (18.1-12% and high (18-25%. The clinical course and complications of infants were compared between the groups. Gestational age (GA was highest and surfactant administration, peak inspiratory pressure requirement, fluid intake, urinary output, oxygen dependent days and the number of oxygen dependent infants at age 28 days were lower in the low MWL compared to the high MWL group. However, all these significant P-values declined after controlling for GA. Diabetes mellitus and pregnancy associated hypertension were not noted in mothers in high MWL group, whereas 38% of mothers in low MWL group suffered from the latter (P=0.05. Maximum postnatal transitional weight loss, assessed in the range of low, moderate and high, is not associated with adverse outcomes independent of gestational age in ELBW infants. Maternal hypertension decreases EPWL in them.

  1. Control challenges for extremely large telescopes

    Science.gov (United States)

    MacMartin, Douglas G.

    2003-08-01

    The next generation of large ground-based optical telescopes are likely to involve a highly segmented primary mirror that must be controlled in the presence of wind and other disturbances, resulting in a new set of challenges for control. The current design concept for the California Extremely Large Telescope (CELT) includes 1080 segments in the primary mirror, with the out-of-plane degrees of freedom actively controlled. In addition to the 3240 primary mirror actuators, the secondary mirror of the telescope will also require at least 5 degree of freedom control. The bandwidth of both control systems will be limited by coupling to structural modes. I discuss three control issues for extremely large telescopes in the context of the CELT design, describing both the status and remaining challenges. First, with many actuators and sensors, the cost and reliability of the control hardware is critical; the hardware requirements and current actuator design are discussed. Second, wind buffeting due to turbulence inside the telescope enclosure is likely to drive the control bandwidth higher, and hence limitations resulting from control-structure-interaction must be understood. Finally, the impact on the control architecture is briefly discussed.

  2. The effect of increase in baggage weight on elderly women's lower extremity muscle activation during gait.

    Science.gov (United States)

    Kim, Seong-Gil; Nam, Chan-Woo; Yong, Min-Sik

    2014-01-01

    The aim of the present study was to examine the effect of increased baggage weight on the muscle activation of elderly women's lower extremities during gait. A total of 24 elderly women who were residing in communities in Daegu, South Korea aged 79.6±6.2, 149.7±7.0cm in height, and 53.5±7.2kg in weight participated in this study. The muscle activation of each muscle was measured three times at 2kg, 3kg, and 4kg of baggage weight while the subjects were conducting treadmill walking wearing backpacks. Electrodes were placed on four muscles: the quadriceps muscle (rectus femoris), the hamstring muscle (semitendinosus), the tibialis anterior muscle, and the soleus muscle. The results show that the rates of increase in muscle activation in the tibialis anterior and soleus muscles according to baggage weight increase were higher than those in the quadriceps and hamstring muscles (<0.05). These results indicate that the heavier weight loads increase the activation of muscles that control the ankle joints causing muscle fatigue. Moreover, a decrease in balance ability through muscle fatigue can be a risk factor for falls. Thus, elderly people should be instructed not to carry heavy objects.

  3. Trisomy 21 in one of extremely low birth weight twins

    OpenAIRE

    Solomon, Benjamin D.; Balachandar, Divya; Perry, Karen; Carrillo-Carrasco, Nuria; Markello, Thomas C.; Rais-Bahrami, Khodayar

    2008-01-01

    Prematurity is frequently seen in the neonatal intensive care unit, and trisomy 21 is an often diagnosed neonatal disorder. We report a unique case of extremely premature twins, one of whom was ultimately diagnosed with trisomy 21. We were able to examine the neonatal courses and outcomes of these twins, which were similar despite the presence of trisomy 21 in one twin. This is the first report comparing the neonatal course of an infant with trisomy 21 to an unaffected twin in patients born s...

  4. Early Vocalization of Preterm Infants with Extremely Low Birth Weight (ELBW), Part I: From Birth to Expansion Stage

    Science.gov (United States)

    Torola, Helena; Lehtihalmes, Matti; Heikkinen, Hanna; Olsen, Paivi; Yliherva, Anneli

    2012-01-01

    The vocalization of preterm infants with extremely low birth weight (ELBW) up to the expansion stage was systematically described and compared with those of healthy full-term infants. The sample consisted of 18 preterm ELBW infants and the control group of 11 full-term infants. The follow-up was performed intensively using video-recordings. The…

  5. Smell-taste dysfunctions in extreme weight/eating conditions: analysis of hormonal and psychological interactions.

    Science.gov (United States)

    Fernández-Aranda, Fernando; Agüera, Zaida; Fernández-García, Jose C; Garrido-Sanchez, Lourdes; Alcaide-Torres, Juan; Tinahones, Francisco J; Giner-Bartolomé, Cristina; Baños, Rosa M; Botella, Cristina; Cebolla, Ausias; de la Torre, Rafael; Fernández-Real, Jose M; Ortega, Francisco J; Frühbeck, Gema; Gómez-Ambrosi, Javier; Granero, Roser; Islam, Mohamed A; Jiménez-Murcia, Susana; Tárrega, Salomé; Menchón, José M; Fagundo, Ana B; Sancho, Carolina; Estivill, Xavier; Treasure, Janet; Casanueva, Felipe F

    2016-02-01

    (1) The objective of this study is to analyze differences in smell-taste capacity between females in extreme weight/eating conditions (EWC) and (2) to explore the interaction between smell/taste capacity, gastric hormones, eating behavior and body mass index (BMI). The sample comprised 239 females in EWC [64 Anorexia nervosa (AN) and 80 age-matched healthy-weight controls, and 59 obese and 36 age-matched healthy-weight controls]. Smell and taste assessments were performed through "Sniffin' Sticks" and "Taste Strips," respectively. The assessment measures included the eating disorders inventory-2, the symptom check list 90-revised, and The Dutch Eating Behavior Questionnaire, as well as peptides from the gastrointestinal tract [Ghrelin, peptide YY, cholecystokinin]. Smell capacity was differentially associated across EWC groups. Smell was clearly impaired in obese participants and increased in AN (hyposmia in Obesity was 54.3 and 6.4 % in AN), but taste capacity did not vary across EWC. Ghrelin levels were significantly decreased in obese subjects and were related to smell impairment. EWC individuals showed a distinct smell profile and circulating ghrelin levels compared to controls. Smell capacity and ghrelin may act as moderators of emotional eating and BMI.

  6. Green teeth are a late complication of prolonged conjugated hyperbilirubinemia in extremely low birth weight infants.

    Science.gov (United States)

    Battineni, Sireesha; Clarke, Paul

    2012-01-01

    Eruption of green, discolored teeth affecting the primary dentition has been described in association with congenital viral infection, sepsis, hemolytic jaundice, and cholestasis. The purpose of this paper was to present the cases of 3 extremely low birth weight preterm infants who were noted to have green teeth at the corrected ages of 10 to 12 months. All had a history of prolonged conjugated hyperbilirubinemia during their time in neonatal intensive care. For infants with prolonged conjugated hyperbilirubinemia, extreme preterm birth and/or extremely low birth weight may be additional risk factors predisposing to the eruption of green teeth in later infancy.

  7. Wavefront Control for Extreme Adaptive Optics

    Energy Technology Data Exchange (ETDEWEB)

    Poyneer, L A

    2003-07-16

    Current plans for Extreme Adaptive Optics systems place challenging requirements on wave-front control. This paper focuses on control system dynamics, wave-front sensing and wave-front correction device characteristics. It may be necessary to run an ExAO system after a slower, low-order AO system. Running two independent systems can result in very good temporal performance, provided specific design constraints are followed. The spatially-filtered wave-front sensor, which prevents aliasing and improves PSF sensitivity, is summarized. Different models of continuous and segmented deformable mirrors are studied. In a noise-free case, a piston-tip-tilt segmented MEMS device can achieve nearly equivalent performance to a continuous-sheet DM in compensating for a static phase aberration with use of spatial filtering.

  8. Delivery of the extremely low-birth- weight vertex-presenting baby ...

    African Journals Online (AJOL)

    2010-12-02

    Dec 2, 2010 ... both mother and baby when delivery of an extremely low- birth-weight infant is inevitable. Over the past few decades there has been a sharp rise in the .... there was any advantage for very-low-birth-weight babies delivered by ...

  9. Wind Turbine Extreme Gust Control. Recognition and Control of extreme operation gusts and wind direction changes

    Energy Technology Data Exchange (ETDEWEB)

    Kanev, S.K.; Van Engelen, T.G. [ECN Wind Energy, Petten (Netherlands)

    2008-10-15

    This report presents the research activities and achieved results on extreme event recognition (EER) and control (EEC). This work has been performed within the framework of WP3 of the SenterNovem project Sustainable Control (SusCon). An extreme wind gust with direction change can lead to large loads on the turbine (causing fatigue) and unnecessary turbine shut-downs by the supervisory system due to rotor overspeed. The proposed EER algorithm is based on a nonlinear observer (extended Kalman filter) that estimates the oblique wind inflow angle and the blade effective wind speed signals, which are then used by a detection algorithm (CUSUM test) to recognize extreme events. The nonlinear observer requires that blade root bending moments measurements (in-plane and out-of-plane) are available. Once an extreme event is detected, an EEC algorithm is activated that (1) tries to prevent the rotor speed from exceeding the overspeed limit by fast collective blade pitching, and (2) reduces 1p blade loads by means of individual pitch control algorithm, designed in an H1 optimal control setting. The method is demonstrated on a complex nonlinear test turbine model.

  10. Indomethacin prophylaxis or expectant treatment of patent ductus arteriosus in extremely low birth weight infants?

    Science.gov (United States)

    Cordero, L; Nankervis, C A; Delooze, D; Giannone, P J

    2007-03-01

    Indomethacin prophylaxis or expectant treatment are common strategies for the prevention or management of symptomatic patent ductus arteriosus (sPDA). To compare the clinical responses of extremely low birth weight (ELBW) infants to indomethacin prophylaxis with that of other infants who were managed expectantly by being treated with indomethacin or surgically only after an sPDA was detected. Retrospective cohort investigation of 167 ELBW infants who received indomethacin prophylaxis (study) and 167 ELBW infants (control) treated expectantly who were matched by year of birth (1999 to 2006), birth weight, gestational age (GA) and gender. Mothers of the two groups of infants were comparable demographically and on the history of preterm labor, pre-eclampsia, antepartum steroids and cesarean delivery. Study and control infants were similar in birth weight, GA, low 5 min Apgar scores, surfactant administration, the need for arterial blood pressure control, bronchopulmonary dysplasia and neonatal mortality. Necrotizing enterocolitis, spontaneous intestinal perforations, intraventricular hemorrhage grade III to IV, periventricular leukomalacia and stage 3 to 5 retinopathy of prematurity occurred also with similar frequency in both groups of infants. In the indomethacin prophylaxis group, 29% of the infants developed sPDA, and of them 38% responded to indomethacin treatment. In the expectantly treated group, 37% developed sPDA, and of them 59% responded to indomethacin treatment. Overall, surgical ligation rate for sPDA was similar between both groups of patients. In our experience, indomethacin prophylaxis does not show any advantages over expectant early treatment on the management of sPDA in ELBW infants. Although no deleterious effects were observed, prophylaxis exposed a significant number of infants who may have never developed sPDA, to potential indomethacin-related complications.

  11. Pattern of learning disabilities in children with extremely low birth weight and broadly average intelligence.

    Science.gov (United States)

    Grunau, Ruth Eckstein; Whitfield, Michael F; Davis, Cynthia

    2002-06-01

    To examine the prevalence and pattern of specific areas of learning disability (LD) in neurologically normal children with extremely low birth weight (ELBW) (intelligence compared with full-term children with normal birth weight of comparable sociodemographic background, and to explore concurrent cognitive correlates of the specific LDs. Longitudinal follow-up; geographically defined region. Regional follow-up program. Wechsler Intelligence Scale for Children-Revised, Gray Oral Reading Test-Revised, Test of Written Language-Revised, Wide Range Achievement Test-Revised, Developmental Test of Visual-Motor Integration. One hundred fourteen (87%) of 131 children with ELBW born between 1982 and 1987 were seen at ages 8 to 9 years. Of the 114 children, 74, who were neurologically normal, with a Verbal or Performance IQ greater than or equal to 85, formed the study group. A group of 30 full-term children with normal birth weight and similar sociodemographic status comprised a comparison group. The children were predominantly white and middle class. Significantly more children with ELBW (65%) met criteria for LD in 1 or more areas compared with 13% of the comparison children. In the ELBW group, the most frequently affected area was written output, then arithmetic, then reading. Visuospatial and visual-motor abilities in combination with verbal functioning primarily explained performance in arithmetic and reading among children with ELBW, unlike the control children, whose scores were associated only with verbal functioning. Complex LDs in multiple academic domains are common sequelae among broadly middle class, predominantly white, neurologically normal children with ELBW compared with control peers. The developmental etiology of LDs in children with ELBW and control peers differs.

  12. FTO gene SNPs associated with extreme obesity in cases, controls and extremely discordant sister pairs

    Directory of Open Access Journals (Sweden)

    Zhao Hongyu

    2008-01-01

    Full Text Available Abstract Background FTO is a gene located in chromosome region 16q12.2. Recently two studies have found associations of several single nucleotide polymorphisms (SNPs in FTO with body mass index (BMI and obesity, particularly rs1421085, rs17817449, and rs9939609. Methods We examined these three SNPs in 583 extremely obese women with current BMI greater than 35 kg/m2 and lifetime BMI greater than 40 kg/m2, and 544 controls who were currently normal weight (BMI2 and had never been overweight during their lifetimes. Results We detected highly significant associations of obesity with alleles in all three SNPs (p -9. The strongest association was with rs1421085 (p = 3.04 × 10-10, OR = 1.75, CI = 1.47–2.08. A subset of 99 cases had extremely discordant sisters with BMI2. The discordant sisters differed in allele and genotype frequencies in parallel with the overall case and control sample. The strongest association was with rs17817449 (z = 3.57, p = 3.6 × 10-4. Conclusion These results suggest common variability in FTO is associated with increased obesity risk or resistance and may in part account for differences between closely related individuals.

  13. Haptic biofeedback for improving compliance with lower-extremity partial weight bearing.

    Science.gov (United States)

    Fu, Michael C; DeLuke, Levi; Buerba, Rafael A; Fan, Richard E; Zheng, Ying Jean; Leslie, Michael P; Baumgaertner, Michael R; Grauer, Jonathan N

    2014-11-01

    After lower-extremity orthopedic trauma and surgery, patients are often advised to restrict weight bearing on the affected limb. Conventional training methods are not effective at enabling patients to comply with recommendations for partial weight bearing. The current study assessed a novel method of using real-time haptic (vibratory/vibrotactile) biofeedback to improve compliance with instructions for partial weight bearing. Thirty healthy, asymptomatic participants were randomized into 1 of 3 groups: verbal instruction, bathroom scale training, and haptic biofeedback. Participants were instructed to restrict lower-extremity weight bearing in a walking boot with crutches to 25 lb, with an acceptable range of 15 to 35 lb. A custom weight bearing sensor and biofeedback system was attached to all participants, but only those in the haptic biofeedback group were given a vibrotactile signal if they exceeded the acceptable range. Weight bearing in all groups was measured with a separate validated commercial system. The verbal instruction group bore an average of 60.3±30.5 lb (mean±standard deviation). The bathroom scale group averaged 43.8±17.2 lb, whereas the haptic biofeedback group averaged 22.4±9.1 lb (Pbiofeedback group averaged 14.5±6.3% (Pbiofeedback to improve compliance with lower-extremity partial weight bearing, haptic biofeedback was superior to conventional physical therapy methods. Further studies in patients with clinical orthopedic trauma are warranted.

  14. Nutrition, Diet, and Weight Control for Athletes.

    Science.gov (United States)

    Heck, Kathy

    1980-01-01

    Athletes can achieve their full potential and develop good eating habits for the future through proper diet and weight control. The basics of nutrition are as important as the basic skills of the sports in which athletes participate. (CJ)

  15. Calcium and weight control-Publications summaries

    Directory of Open Access Journals (Sweden)

    Feride Çelebi

    2011-08-01

    Full Text Available Obesity is a public health problem. And it is known that both energy balance and nutritional factors are effective on it. The effects of dietary calcium on bone health are known however with recent studies, it has become a food item that focused on the effect on body weight control. Most epidemiyolojik studies claim that there is a relationship between long-term consumption of diary milk and milk products and the decrease of body weight and fat mass. In this article, there are different studies that support or do not support this idea. However the effect mechanism of calcium on weight control is tried to be explained.

  16. Additional Protein Fortification Is Necessary in Extremely Low-Birth-Weight Infants Fed Human Milk.

    Science.gov (United States)

    Picaud, Jean-Charles; Houeto, Nellie; Buffin, Rachel; Loys, Claire-Marie; Godbert, Isabelle; Haÿs, Stephane

    2016-07-01

    In the present study, approximately one in three (49/152, 32.2%) extremely low-birth-weight infants were demonstrated to require additional protein intake to supplement the standard fortification to achieve satisfactory weight gain. This additional protein fortification also resulted in a rapid increase in length-for-age (P < 0.001) and head circumference-for-age (P = 0.02) z scores.

  17. A Prospective Study of Extreme Weight Change Behaviors among Adolescent Boys and Girls

    Science.gov (United States)

    McCabe, Marita P.; Ricciardelli, Lina A.

    2006-01-01

    This study examined changes in extreme weight change attitudes and behaviors (exercise dependence, food supplements, drive for thinness, bulimia) among adolescent boys and girls over a 16 month period. It also investigated the impact of body mass index, puberty, body image, depression and positive affect on these attitudes and behaviors 16 months…

  18. Serum magnesium in the first week of life in extremely low birth weight infants.

    LENUS (Irish Health Repository)

    Noone, D

    2012-01-01

    Evidence that antenatal administration of magnesium sulfate (MgSO(4)) to women in preterm labor may confer fetal neuroprotection is growing. MgSO(4) crosses the placenta and can affect the neonate. Magnesium homeostasis in extremely low birth weight (ELBW) infants remains to be clarified.

  19. General movements in the first fourteen days of life in extremely low birth weight (ELBW) infants

    NARCIS (Netherlands)

    de Vries, N. K. S.; Erwich, J. J. H. M.; Bos, A. F.

    2008-01-01

    Objective: To assess the quality of general movements (GMs) in the first fourteen days of life in relation to obstetric and postnatal risk factors and neurodevelopmental outcome in extremely low birth weight (ELBW) infants. Study design: The GMs of nineteen infants were assessed on days 2, 4, 6, 10

  20. Does Extremely Low Birth Weight Predispose to Low-Renin Hypertension?

    Science.gov (United States)

    Raaijmakers, Anke; Zhang, Zhen-Yu; Claessens, Jolien; Cauwenberghs, Nicholas; van Tienoven, Theun Pieter; Wei, Fang-Fei; Jacobs, Lotte; Levtchenko, Elena; Pauwels, Steven; Kuznetsova, Tatiana; Allegaert, Karel; Staessen, Jan A

    2017-03-01

    Low birth weight and prematurity are risk factors for hypertension in adulthood. Few studies in preterm or full-term born children reported on plasma renin activity (PRA). We tested the hypothesis that renin might modulate the incidence of hypertension associated with prematurity. We enrolled 93 prematurely born children with birth weight hypertension associated with extreme low birth weight were 6.43 (2.52-16.4; Phypertension, but does not affect the inverse association between PRA and BP. URL: https://www.clinicaltrials.gov. Unique identifier: NCT02147457. © 2017 American Heart Association, Inc.

  1. Executive functions profile in extreme eating/weight conditions: from anorexia nervosa to obesity.

    Directory of Open Access Journals (Sweden)

    Ana B Fagundo

    Full Text Available BACKGROUND: Extreme weight conditions (EWC groups along a continuum may share some biological risk factors and intermediate neurocognitive phenotypes. A core cognitive trait in EWC appears to be executive dysfunction, with a focus on decision making, response inhibition and cognitive flexibility. Differences between individuals in these areas are likely to contribute to the differences in vulnerability to EWC. The aim of the study was to investigate whether there is a common pattern of executive dysfunction in EWC while comparing anorexia nervosa patients (AN, obese subjects (OB and healthy eating/weight controls (HC. METHODS: Thirty five AN patients, fifty two OB and one hundred thirty seven HC were compared using the Wisconsin Card Sorting Test (WCST; Stroop Color and Word Test (SCWT; and Iowa Gambling Task (IGT. All participants were female, aged between 18 and 60 years. RESULTS: There was a significant difference in IGT score (F(1.79; p<.001, with AN and OB groups showing the poorest performance compared to HC. On the WCST, AN and OB made significantly more errors than controls (F(25.73; p<.001, and had significantly fewer correct responses (F(2.71; p<.001. Post hoc analysis revealed that the two clinical groups were not significantly different from each other. Finally, OB showed a significant reduced performance in the inhibition response measured with the Stroop test (F(5.11; p<.001 compared with both AN and HC. CONCLUSIONS: These findings suggest that EWC subjects (namely AN and OB have similar dysfunctional executive profile that may play a role in the development and maintenance of such disorders.

  2. Asymptotically extremal polynomials with respect to varying weights and application to Sobolev orthogonality

    Science.gov (United States)

    Díaz Mendoza, C.; Orive, R.; Pijeira Cabrera, H.

    2008-10-01

    We study the asymptotic behavior of the zeros of a sequence of polynomials whose weighted norms, with respect to a sequence of weight functions, have the same nth root asymptotic behavior as the weighted norms of certain extremal polynomials. This result is applied to obtain the (contracted) weak zero distribution for orthogonal polynomials with respect to a Sobolev inner product with exponential weights of the form e-[phi](x), giving a unified treatment for the so-called Freud (i.e., when [phi] has polynomial growth at infinity) and Erdös (when [phi] grows faster than any polynomial at infinity) cases. In addition, we provide a new proof for the bound of the distance of the zeros to the convex hull of the support for these Sobolev orthogonal polynomials.

  3. The 5-minute Apgar score: survival and short-term outcomes in extremely low-birth-weight infants.

    Science.gov (United States)

    Phalen, Ann Gibbons; Kirkby, Sharon; Dysart, Kevin

    2012-01-01

    The Apgar score is a standardized tool for evaluating newborns in the delivery room. Despite its long history and widespread use, debate remains over its reliability of predicting neonatal outcomes, especially in extremely low-birth-weight premature infants. The aim of the study was to examine the relationship between the 5-minute Apgar score of extremely low-birth-weight infants, as it relates to survival and morbidities associated with prematurity and length of hospital stay. A retrospective query of the Alere neonatal database from 2001 to 2011 examined all infants less than 32 weeks' gestation and less than 1000-g birth weight. The 5-minute Apgar score was divided into 2 groups, score of 4 or greater or less than 4. The study compared results of the 5-minute Apgar score and associated morbidities in surviving infants. Statistical analyses included chi-square, Fisher exact test, t test, and multivariate regression. The sample consisted of 3898 infants with an 86.4% (n = 3366) survival rate. Controlling for gestational age and birth weight, surviving infants with a 5-minute Apgar score of less than 4 were more likely to demonstrate nonintact survival. Infants with a low 5-minute Apgar score have greater risk for mortality and morbidities associated with prematurity.

  4. Neighboring extremal optimal control design including model mismatch errors

    Energy Technology Data Exchange (ETDEWEB)

    Kim, T.J. [Sandia National Labs., Albuquerque, NM (United States); Hull, D.G. [Texas Univ., Austin, TX (United States). Dept. of Aerospace Engineering and Engineering Mechanics

    1994-11-01

    The mismatch control technique that is used to simplify model equations of motion in order to determine analytic optimal control laws is extended using neighboring extremal theory. The first variation optimal control equations are linearized about the extremal path to account for perturbations in the initial state and the final constraint manifold. A numerical example demonstrates that the tuning procedure inherent in the mismatch control method increases the performance of the controls to the level of a numerically-determined piecewise-linear controller.

  5. The Effect of the Weight of Equipment on Muscle Activity of the Lower Extremity in Soldiers

    Directory of Open Access Journals (Sweden)

    Tobias Lindner

    2012-01-01

    Full Text Available Due to their profession and the tasks it entails, soldiers are exposed to high levels of physical activity and strain. This can result in overexertion and pain in the locomotor system, partly caused by carrying items of equipment. The aim of this study was to analyse the extent of muscle activity in the lower extremities caused by carrying specific items of equipment. For this purpose, the activity of selected groups of muscles caused by different items of equipment (helmet, carrying strap, backpack, and rifle in the upper and lower leg was measured by recording dynamic surface electromyograms. Electrogoniometers were also used to measure the angle of the knee over the entire gait cycle. In addition to measuring muscle activity, the study also aimed to determine out what influence increasing weight load has on the range of motion (ROM of the knee joint during walking. The activity of recorded muscles of the lower extremity, that is, the tibialis anterior, peroneus longus, gastrocnemius lateralis, gastrocnemius medialis, rectus femoris, and biceps femoris, was found to depend on the weight of the items of equipment. There was no evidence, however, that items of equipment weighing a maximum of 34% of their carrier’s body weight had an effect on the ROM of the knee joint.

  6. Marrow signal mimicking tumor on MRI T1-weighted imaging after neoadjuvant chemotherapy in extremity osteosarcomas

    Directory of Open Access Journals (Sweden)

    Zhiping Deng

    2017-03-01

    Conclusions: Neoadjuvant chemotherapy for extremity osteosarcoma can result in a variety of changes of the MRI appearance of tumor and adjacent bone and marrow. Areas of signal change beyond the tumor that represent marrow conversion and not tumor progression appear on T1 weighted imaging to be lower in signal than subcutaneous fat and higher in signal than muscle. Recognizing the existence of the effect of neoadjuvant chemotherapy on the MR appearance of the tumor and surrounding bone and myeloid elements is important so as to plan for oncological sound tumor resections while avoiding resecting more normal bone than necessary.

  7. Developmental coordination disorder in extremely low birth weight children at nine years.

    Science.gov (United States)

    Holsti, Liisa; Grunau, Ruth V E; Whitfield, Michael F

    2002-02-01

    Developmental coordination disorder (DCD) is defined as an impairment in the development of motor coordination that interferes with academic achievement or activities of daily living (DSM-IV). DCD has been reported to affect 5% to 9% of children in the normal population. This study describes the prevalence of DCD in a cohort of extremely low birth weight children (ELBW, DCD. ELBW children with DCD also had significantly lower Performance IQ (PIQ) scores and were more likely (43%) to have a learning difficulty in arithmetic than ELBW children who did not have DCD. This study found that DCD is a common problem in school-aged ELBW children.

  8. Internet-Based Weight Control: The Relationship Between Web Features and Weight Loss

    OpenAIRE

    Krukowski, Rebecca A.; Harvey-Berino, Jean; Ashikaga, Takamaru; Thomas, Colleen S.; Micco, Nicci

    2008-01-01

    Internet-based weight control programs have been showing promising results; however, as of yet, it is unclear which website components are critical for producing and maintaining weight loss. The aim of this study is to examine the utilization patterns of a weight control website and the relationship of the Web features to weight loss and maintenance. One hundred and twenty three (N = 123) participants took part in a 12-month behavioral weight control program over the Internet and their websit...

  9. Constraint Algorithm for Extremals in Optimal Control Problems

    CERN Document Server

    Barbero-Linan, Maria

    2007-01-01

    A characterization of different kinds of extremals of optimal control problems is given if we take an open control set. A well known constraint algorithm for implicit differential equations is adapted to the study of such problems. Some necessary conditions of Pontryagin's Maximum Principle determine the primary constraint submanifold for the algorithm. Some examples in the control literature, such as subRiemannian geometry and control-affine systems, are revisited to give, in a clear geometric way, a subset where the abnormal, normal and strict abnormal extremals stand.

  10. Changes in lower extremity muscle mass and muscle strength after weight loss in obese patients with knee osteoarthritis

    DEFF Research Database (Denmark)

    Henriksen, Marius; Christensen, Robin; Danneskiold-Samsøe, Bente

    2012-01-01

    To investigate the effects of low-energy diet-induced weight loss on lower-extremity muscle mass and knee muscle strength in obese patients with knee osteoarthritis (OA), and the associations of these effects.......To investigate the effects of low-energy diet-induced weight loss on lower-extremity muscle mass and knee muscle strength in obese patients with knee osteoarthritis (OA), and the associations of these effects....

  11. The contribution of visual processing to academic achievement in adolescents born extremely preterm or extremely low birth weight.

    Science.gov (United States)

    Molloy, Carly S; Di Battista, Ashley M; Anderson, Vicki A; Burnett, Alice; Lee, Katherine J; Roberts, Gehan; Cheong, Jeanie Ly; Anderson, Peter J; Doyle, Lex W

    2017-04-01

    Children born extremely preterm (EP, visual processing. The aim of this study is to determine (1) if visual processing is related to poor academic outcomes in EP/ELBW adolescents, and (2) how much of the variance in academic achievement in EP/ELBW adolescents is explained by visual processing ability after controlling for perinatal risk factors and other known contributors to academic performance, particularly attention and working memory. A geographically determined cohort of 228 surviving EP/ELBW adolescents (mean age 17 years) was studied. The relationships between measures of visual processing (visual acuity, binocular stereopsis, eye convergence, and visual perception) and academic achievement were explored within the EP/ELBW group. Analyses were repeated controlling for perinatal and social risk, and measures of attention and working memory. It was found that visual acuity, convergence and visual perception are related to scores for academic achievement on univariable regression analyses. After controlling for potential confounds (perinatal and social risk, working memory and attention), visual acuity, convergence and visual perception remained associated with reading and math computation, but only convergence and visual perception are related to spelling. The additional variance explained by visual processing is up to 6.6% for reading, 2.7% for spelling, and 2.2% for math computation. None of the visual processing variables or visual motor integration are associated with handwriting on multivariable analysis. Working memory is generally a stronger predictor of reading, spelling, and math computation than visual processing. It was concluded that visual processing difficulties are significantly related to academic outcomes in EP/ELBW adolescents; therefore, specific attention should be paid to academic remediation strategies incorporating the management of working memory and visual processing in EP/ELBW children.

  12. Associations of body weight perception and weight control behaviors with problematic internet use among Korean adolescents.

    Science.gov (United States)

    Park, Subin; Lee, Yeeun

    2017-02-08

    We examined the association of body mass index (BMI), body weight perception, and weight control behaviors with problematic Internet use in a nationwide sample of Korean adolescents. Cross-sectional data from the 2010 Korean Youth Risk Behavior Web-based Survey collected from 37,041 boys and 33,655 girls in middle- and high- schools (grades 7-12) were analyzed. Participants were classified into groups based on BMI (underweight, normal weight, overweight, and obese), body weight perception (underweight, normal weight, and overweight), and weight control behavior (no weight control behavior, appropriate weight control behavior, inappropriate weight control behavior). The risk of problematic Internet use was assessed with the Korean Internet Addiction Proneness Scale for Youth-Short Form. Both boys and girls with inappropriate weight control behavior were more likely to have problematic Internet use. Underweight, overweight, and obese boys and girls were more likely to have problematic Internet use. For both boys and girls, subjective perception of underweight and overweight were positively associated with problematic Internet use. Given the negative effect of inappropriate weight control behavior, special attention needs to be given to adolescents' inappropriate weight control behavior, and an educational intervention for adolescents to control their weight in healthy ways is needed.

  13. Extreme events in multilayer, interdependent complex networks and control

    Science.gov (United States)

    Chen, Yu-Zhong; Huang, Zi-Gang; Zhang, Hai-Feng; Eisenberg, Daniel; Seager, Thomas P.; Lai, Ying-Cheng

    2015-11-01

    We investigate the emergence of extreme events in interdependent networks. We introduce an inter-layer traffic resource competing mechanism to account for the limited capacity associated with distinct network layers. A striking finding is that, when the number of network layers and/or the overlap among the layers are increased, extreme events can emerge in a cascading manner on a global scale. Asymptotically, there are two stable absorption states: a state free of extreme events and a state of full of extreme events, and the transition between them is abrupt. Our results indicate that internal interactions in the multiplex system can yield qualitatively distinct phenomena associated with extreme events that do not occur for independent network layers. An implication is that, e.g., public resource competitions among different service providers can lead to a higher resource requirement than naively expected. We derive an analytical theory to understand the emergence of global-scale extreme events based on the concept of effective betweenness. We also articulate a cost-effective control scheme through increasing the capacity of very few hubs to suppress the cascading process of extreme events so as to protect the entire multi-layer infrastructure against global-scale breakdown.

  14. Self-perception of body weight status and weight control practices among adolescents in Malaysia.

    Science.gov (United States)

    Zainuddin, Ahmad Ali; Manickam, Mala A; Baharudin, Azli; Omar, Azahadi; Cheong, Siew Man; Ambak, Rashidah; Ahmad, Mohamad Hasnan; Ghaffar, Suhaila Abdul

    2014-09-01

    The prevalence of overweight and obesity among adolescents is rising rapidly in many countries, including Malaysia. This article aims to present the associations between body mass index-based body weight status, body weight perception, and weight control practices among adolescents in Malaysia. The Malaysia School Based Nutrition Survey 2012, which included a body weight perception questionnaire and anthropometric measurements, was conducted on a representative sample of 40 011 students from Standard 4 until Form 5, with a 90.5% response rate. Comparing actual and perceived body weight status, the findings show that 13.8% of adolescents underestimated their weight, 35.0% overestimated, and 51.2% correctly judged their own weight. Significantly more normal weight girls felt they were overweight, whereas significantly more overweight boys perceived themselves as underweight. The overall appropriateness of weight control practices to body weight was 72.6%. Adolescents attempting to lose or gain weight need to have better understanding toward desirable behavioral changes.

  15. Upper extremity sensorimotor control among collegiate football players.

    Science.gov (United States)

    Laudner, Kevin G

    2012-03-01

    Injuries stemming from shoulder instability are very common among athletes participating in contact sports, such as football. Previous research has shown that increased laxity negatively affects the function of the sensorimotor system potentially leading to a pathological cycle of shoulder dysfunction. Currently, there are no data detailing such effects among football players. Therefore, the purpose of this study was to examine the differences in upper extremity sensorimotor control among football players compared with that of a control group. Forty-five collegiate football players and 70 male control subjects with no previous experience in contact sports participated. All the subjects had no recent history of upper extremity injury. Each subject performed three 30-second upper extremity balance trials on each arm. The balance trials were conducted in a single-arm push-up position with the test arm in the center of a force platform and the subjects' feet on a labile device. The trials were averaged, and the differences in radial area deviation between groups were analyzed using separate 1-way analyses of variance (p football players showed significantly more radial area deviation of the dominant (0.41 ± 1.23 cm2, p = 0.02) and nondominant arms (0.47 ± 1.63 cm2, p = 0.03) when compared with the control group. These results suggest that football players may have decreased sensorimotor control of the upper extremity compared with individuals with no contact sport experience. The decreased upper extremity sensorimotor control among the football players may be because of the frequent impacts accumulated during football participation. Football players may benefit from exercises that target the sensorimotor system. These findings may also be beneficial in the evaluation and treatment of various upper extremity injuries among football players.

  16. Gluconeogenesis is Not Regulated by Either Glucose or Insulin in Extremely Low Birth Weight Infants Receiving Total Parenteral Nutrition

    NARCIS (Netherlands)

    Chacko, Shaji K.; Ordonez, Jorge; Sauer, Pieter J. J.; Sunehag, Agneta L.

    2011-01-01

    Objective To determine potential factors regulating gluconeogenesis (GNG) in extremely low birth weight infants receiving total parenteral nutrition. Study design Seven infants (birth weight, 0.824 +/- 0.068 kg; gestational age, 25.4 +/- 0.5 weeks; postnatal age, 3.3 +/- 0.2 days) were studied for 1

  17. How College Students Search the Internet for Weight Control and Weight Management Information: An Observational Study

    Science.gov (United States)

    Senkowski, Valerie; Branscum, Paul

    2015-01-01

    Background: Few studies have attempted to examine how young adults search for health information on the Internet, especially information related to weight control and weight management. Purpose: The purpose of this study was to determine search strategies that college students used for finding information related to weight control and weight…

  18. How College Students Search the Internet for Weight Control and Weight Management Information: An Observational Study

    Science.gov (United States)

    Senkowski, Valerie; Branscum, Paul

    2015-01-01

    Background: Few studies have attempted to examine how young adults search for health information on the Internet, especially information related to weight control and weight management. Purpose: The purpose of this study was to determine search strategies that college students used for finding information related to weight control and weight…

  19. An extremely low body weight infant born to a mother with measles.

    Science.gov (United States)

    Go, H; Hashimoto, K; Imamura, T; Sato, M; Kawasaki, Y; Momoi, N; Hosoya, M

    2010-02-01

    The incidence of measles epidemics has decreased recently owing to the development and widespread use of measles vaccine in the United States of America and Europe. However, repeated measles epidemics have been reported in Japan. Here, the authors report a case of an extremely low body weight infant (ELBWI) whose mother had a measles virus infection. Real-time PCR was performed on the infant's blood and urine samples and skin, nasal secretion, and anal swabs, as well as on the mother's breast milk, blood samples and throat swabs. The infant was found to be positive for measles virus by PCR, but not immunoglobulin M positive. An earlier report showed that there were no such cases in which the patient was found to be positive for measles virus by real-time PCR but was not infected by the measles virus.

  20. Disseminated candidemia refractory to caspofungin therapy in an infant with extremely low birth weight

    Directory of Open Access Journals (Sweden)

    Meng-Ju Li

    2012-01-01

    Full Text Available Systemic fungal infections have high morbidity and mortality rates in neonates, especially neonates with an extremely low birth weight (ELBW. Here, we describe a 21-day-old ELBW female infant with an amphotericin B-unresponsive congenital Candida albicans infection that was treated with caspofungin. Blood sterilization was performed during the first episode, but a second episode of candidemia occurred after the discontinuation of caspofungin. Blood sterilization was again performed during the second round of caspofungin treatment, but fungal endocarditis and renal fungal balls still developed during the second episode. Caspofungin can be considered for invasive candidiasis in premature infants, especially in life-threatening situations. As for the focal lesions, more aggressive treatments other than just parenteral antibiotics should be considered. The literature regarding caspofungin therapy for neonatal candidiasis is also reviewed.

  1. Linking Early Adversity, Emotion Dysregulation, and Psychopathology: The Case of Extremely Low Birth Weight Infants

    Directory of Open Access Journals (Sweden)

    Lauren A. Drvaric

    2013-01-01

    Full Text Available The ability to regulate emotion is a crucial process that humans utilize in order to adapt to the demands of environmental constraints. Individuals exposed to early adverse life events such as being born at an extremely low birth weight (ELBW, 501–1000 g are known to have problems regulating emotion which have been linked to the development of psychopathology in this population. Recent studies have used psychophysiological measures, such as electroencephalogram (EEG and cardiac vagal tone, to index emotion regulatory processes. The purpose of this paper was three-fold: (1 to investigate the relation between ELBW and emotion regulation issues (pathway 1, (2 to review studies investigating the relation between early emotion regulation and later internalizing problems (pathway 2; and (3 to provide a model in which two psychophysiological measures (i.e., frontal EEG asymmetry and cardiac vagal tone are suggested to understand the proposed conceptual pathways in the relation between ELBW and psychopathology.

  2. [Nutritional dilemmas in extremely low birth weight infants and their effects on childhood, adolescence and adulthood].

    Science.gov (United States)

    Camelo, José Simon; Martinez, Francisco Eulógio

    2005-03-01

    To review the recent medical literature on nutrition of extremely low birth weight infants, focusing on nutritional disorders and their effects on childhood, adolescence and adulthood. An extensive review of the related literature was performed using MEDLINE, the Cochrane Database of Systematic Reviews and the Best Evidence database. There is a growing body of evidence that early nutritional practices may affect short-term growth and development outcome. In addition, these practices may play a role in determining adult health and disease. There is still much to be learned about safe and efficacious nutrient administration in preterm infants; about techniques to assess the effect of different nutritional strategies; and about the long-term effects of these regimens on development outcome, growth and disease. Despite recent progress in neonatal nutrition, there is a lack of basic and clinical research to better define the nutritional requirements of preterm infants and the best way to meet these requirements, avoiding long-term undesirable consequences.

  3. Azithromycin in the extremely low birth weight infant for the prevention of Bronchopulmonary Dysplasia: a pilot study

    Directory of Open Access Journals (Sweden)

    Anstead Michael I

    2007-06-01

    Full Text Available Abstract Background Azithromycin reduces the severity of illness in patients with inflammatory lung disease such as cystic fibrosis and diffuse panbronchiolitis. Bronchopulmonary dysplasia (BPD is a pulmonary disorder which causes significant morbidity and mortality in premature infants. BPD is pathologically characterized by inflammation, fibrosis and impaired alveolar development. The purpose of this study was to obtain pilot data on the effectiveness and safety of prophylactic azithromycin in reducing the incidence and severity of BPD in an extremely low birth weight (≤ 1000 grams population. Methods Infants ≤ 1000 g birth weight admitted to the University of Kentucky Neonatal Intensive Care Unit (level III, regional referral center from 9/1/02-6/30/03 were eligible for this pilot study. The pilot study was double-blinded, randomized, and placebo-controlled. Infants were randomized to treatment or placebo within 12 hours of beginning mechanical ventilation (IMV and within 72 hours of birth. The treatment group received azithromycin 10 mg/kg/day for 7 days followed by 5 mg/kg/day for the duration of the study. Azithromycin or placebo was continued until the infant no longer required IMV or supplemental oxygen, to a maximum of 6 weeks. Primary endpoints were incidence of BPD as defined by oxygen requirement at 36 weeks gestation, post-natal steroid use, days of IMV, and mortality. Data was analyzed by intention to treat using Chi-square and ANOVA. Results A total of 43 extremely premature infants were enrolled in this pilot study. Mean gestational age and birth weight were similar between groups. Mortality, incidence of BPD, days of IMV, and other morbidities were not significantly different between groups. Post-natal steroid use was significantly less in the treatment group [31% (6/19] vs. placebo group [62% (10/16] (p = 0.05. Duration of mechanical ventilation was significantly less in treatment survivors, with a median of 13 days (1–47

  4. Gender and Socioeconomic Status in Relation to Weight Perception and Weight Control Behavior in Korean Adults

    National Research Council Canada - National Science Library

    Joh, Hee-Kyung; Oh, Juhwan; Lee, Hae-Jeung; Kawachi, Ichiro

    2013-01-01

    In Korea, obesity is more prevalent among men and lower socioeconomic groups. To explain this obesity disparity, we compared weight perception and weight control behavior across gender and socioeconomic status (SES...

  5. Lower-extremity weight-bearing compliance is maintained over time after biofeedback training.

    Science.gov (United States)

    Hustedt, Joshua W; Blizzard, Daniel J; Baumgaertner, Michael R; Leslie, Michael P; Grauer, Jonathan N

    2012-11-01

    Previous studies have shown immediate compliance with weight-bearing instructions to be better after biofeedback training than after verbal or scale training. This study assessed retention of biofeedback training to determine potential clinical applicability. Twelve participants were enrolled in a prospective clinical study at an academic orthopedic center. Participants were trained with a biofeedback device to comply with touch-down weight-bearing instructions (25 lb). Immediately following the training session, weight bearing was assessed for each participant. The retention of this training was then reassessed at 2 to 4, 6 to 8, and 22 to 24 hours. Two control participants were given no biofeedback training (verbal instructions only) and were followed similarly. Following initial biofeedback training at 25 lb, participants bore an average of 20.4±2.12 lb. Retention tests during the 24-hour period showed no significant difference from the original testing, with 2- to 4-hour retention of 19.98±4.75 lb, 6- to 8-hour retention of 25.07±6.60 lb, and 22- to 24-hour retention of 21.75±4.58 lb. Participants who only received verbal instructions consistently bore several-fold greater weight than instructed. Biofeedback training has previously been shown to have a strong immediate effect on partial weight-bearing compliance. This study demonstrated that this effect lasts up to 24 hours. This maintained weight-bearing compliance after biofeedback training suggests that this method may be an effective way to train patients to comply with given instructions for limited weight bearing.

  6. Abnormalities in orbitofrontal cortex gyrification and mental health outcomes in adolescents born extremely preterm and/or at an extremely low birth weight.

    Science.gov (United States)

    Ganella, Eleni P; Burnett, Alice; Cheong, Jeanie; Thompson, Deanne; Roberts, Gehan; Wood, Stephen; Lee, Katherine; Duff, Julianne; Anderson, Peter J; Pantelis, Christos; Doyle, Lex W; Bartholomeusz, Cali

    2015-03-01

    Extremely preterm (EP, orbitofrontal cortex (OFC) are determined during the third trimester, however little is known about OFC patterning in EP/ELBW cohorts, for whom this gestational period is disturbed. This study investigated whether the distribution of OFC pattern types and frequency of intermediate and/or posterior orbital sulci (IOS/POS) differed between EP/ELBW and control adolescents. This study also investigated whether OFC pattern type was associated with mental illness or executive function outcome in adolescence. Magnetic resonance images of 194 EP/ELBW and 147 full term (>37 completed weeks) and/or normal birth weight (> 2500 g) adolescents were acquired, from which the OFC pattern of each hemisphere was classified as Type I, II, or III. Compared with controls, more EP/ELBW adolescents possessed a Type II in the left hemisphere (P = 0.019). The EP/ELBW group had fewer IOS (P = 0.024) and more POS (P = 0.021) in the left hemisphere compared with controls. OFC pattern type was not associated with mental illness, however in terms of executive functioning, Type III in the left hemisphere was associated with better parent-reported metacognition scores overall (P = 0.008) and better self-reported behavioral regulation scores in the control group (P = 0.001) compared with Type I. We show, for the first time that EP/ELBW birth is associated with changes in orbitofrontal development, and that specific patterns of OFC folding are associated with executive function at age 18 years in both EP/ELBW and control subjects.

  7. Modification of Hidden Layer Weight in Extreme Learning Machine Using Gain Ratio

    Directory of Open Access Journals (Sweden)

    Anggraeny Fetty Tri

    2016-01-01

    Full Text Available Extreme Learning Machine (ELM is a method of learning feed forward neural network quickly and has a fairly good accuracy. This method is devoted to a feed forward neural network with one hidden layer where the parameters (i.e. weight and bias are adjusted one time randomly at the beginning of the learning process. In neural network, the input layer is connected to all characteristics/features, and the output layer is connected to all classes of species. This research used three datasets from UCI database, which were Iris, Breast Wisconsin, and Dermatology, with each dataset having several features. Each characteristic/feature of the data has a role in the process of classification levels, starting from the most influencing role to non-influencing at all. Gain ratio was used to extract each feature role on each datasets. Gain ratio is a method to extract feature role in order to develop a decision tree structure. In this study, ELM structure has been modified, where the random weights of the hidden layer were adjusted to the level of each feature role in determining the species class, so as to improve the level of training and testing accuracy. The proposed method has higher classification accuracy rate than basic ELM on all three datasets, which were 99%, 96%, and 82%, respectively.

  8. Adult social outcomes of extremely low birth weight survivors of childhood sexual abuse.

    Science.gov (United States)

    Lund, J I; Day, K L; Schmidt, L A; Saigal, S; Van Lieshout, R J

    2016-12-01

    Preterm birth and exposure to childhood sexual abuse (CSA) are early physiological and psychological adversities that have been linked to reduced social functioning across the lifespan. However, the joint effects of being born preterm and being exposed to CSA on adult social outcomes remains unclear. We sought to determine the impact of exposure to both preterm birth and CSA on adult social functioning in a group of 179 extremely low birth weight (ELBW; 2500 g) participants in the fourth decade of life. Social outcome data from a prospective, longitudinal, population-based Canadian birth cohort initiated between the years of 1977 and 1982 were examined. At age 29-36 years, ELBW survivors who experienced CSA reported poorer relationships with their partner, worse family functioning, greater loneliness, lower self-esteem and had higher rates of avoidant personality problems than those who had not experienced CSA. Birth weight status was also found to moderate associations between CSA and self-esteem (P=0.032), loneliness (P=0.021) and family functioning (P=0.060), such that the adverse effects of CSA were amplified in ELBW survivors. Exposure to CSA appears to augment the adult social risks associated with perinatal adversity. Individuals born preterm and exposed to CSA appear to be a group at particularly high risk for adverse social outcomes in adulthood.

  9. Controllable gaussian-qubit interface for extremal quantum state engineering.

    Science.gov (United States)

    Adesso, Gerardo; Campbell, Steve; Illuminati, Fabrizio; Paternostro, Mauro

    2010-06-18

    We study state engineering through bilinear interactions between two remote qubits and two-mode gaussian light fields. The attainable two-qubit states span the entire physically allowed region in the entanglement-versus-global-purity plane. Two-mode gaussian states with maximal entanglement at fixed global and marginal entropies produce maximally entangled two-qubit states in the corresponding entropic diagram. We show that a small set of parameters characterizing extremally entangled two-mode gaussian states is sufficient to control the engineering of extremally entangled two-qubit states, which can be realized in realistic matter-light scenarios.

  10. Selective deficit in spatial location memory in extremely low birth weight children at age six: the PETIT study.

    Science.gov (United States)

    Baron, Ida Sue; Brandt, Jason; Ahronovich, Margot D; Baker, Robin; Erickson, Kristine; Litman, Fern R

    2012-01-01

    Spatial location memory has rarely been assessed in young children due to a scarcity of developmentally appropriate tests. This study sought to compare nonverbal learning and recall in children born extremely low birth weight (ELBW; children at early school age using a recently developed and adapted test. We administered a modification of the Hopkins Board to 210 children at age six; 84 born ELBW (35 born children had worse general cognition, item naming, delayed item recall, delayed location recall, and percent retention than term-born children. Delayed item recall and percent retention performances of ELBW children remained worse after correction for general cognition. ELBW groups (children in naming and delayed item recall with chronological age as covariate. Those born before 26 GW, but not 26-33 GW, performed worse than term-born children in delayed location recall and percent retention. Differences remained significant after controlling for gender, maternal education, and delivery type. All three groups' performance declined from final learning trial to delayed location recall, with a decline greater for less than 26 GW than term-born children. Extreme prematurity (spatial location memory deficit. The modified Hopkins Board discriminated high-risk preterm and term-born children at early school age and appears to be a useful test to measure this rarely studied cognitive capacity.

  11. Weight Self-Regulation Process in Adolescence: The Relationship between Control Weight Attitudes, Behaviors, and Body Weight Status

    OpenAIRE

    Jordi ePich; Maria del Mar eBibiloni; Antoni ePons; Tur, Josep A

    2015-01-01

    Adolescents’ self-control weight behaviors were assessed (N = 1961; 12–17 years old; 2007–2008) in the Balearic Islands, Spain. The study analyzed the relationships between body weight status, body image, and self-weight concern, and actual attempts to lose weight by restrained eating and/or increased exercising. In terms of regulatory focus theory (RFT), we considered that efforts to lose or to maintain weight (successful or failed) would be motivated either by a “promotion focus” (to show a...

  12. Learning Disabilities in Extremely Low Birth Weight Children and Neurodevelopmental Profiles at Preschool Age.

    Science.gov (United States)

    Squarza, Chiara; Picciolini, Odoardo; Gardon, Laura; Giannì, Maria L; Murru, Alessandra; Gangi, Silvana; Cortinovis, Ivan; Milani, Silvano; Mosca, Fabio

    2016-01-01

    At school age extremely low birth weight (ELBW) and extremely low gestational age (ELGAN) children are more likely to show Learning Disabilities (LDs) and difficulties in emotional regulation. The aim of this study was to investigate the incidence of LDs at school age and to detect neurodevelopmental indicators of risk for LDs at preschool ages in a cohort of ELBW/ELGAN children with broadly average intelligence. All consecutively newborns 2001-2006 admitted to the same Institution entered the study. Inclusion criteria were BW disabilities, genetic abnormalities, and/or a Developmental Quotient below normal limits (learning disabilities at school age was investigated through a parent-report questionnaire at children's age range 9-10 years. Neurodevelopmental profiles were assessed through the Griffiths Mental Development Scales at 1 and 2 years of corrected age and at 3, 4, 5, and 6 years of chronological age and were analyzed comparing two groups of children: those with LDs and those without. At school age 24 on 102 (23.5%) of our ELBW/ELGAN children met criteria for LDs in one or more areas, with 70.8% comorbidity with emotional/attention difficulties. Children with LDs scored significantly lower in the Griffiths Locomotor and Language subscales at 2 years of corrected age and in the Personal-social, Performance and Practical Reasoning subscales at 5 years of chronological age. Our findings suggest that, among the early developmental indicators of adverse school outcome, there is a poor motor experimentation, language delay, and personal-social immaturity. Cognitive rigidity and poor ability to manage practical situations also affect academic attainment. Timely detection of these early indicators of risk is crucial to assist the transition to school.

  13. Control of the California Extremely Large Telescope primary mirror

    Science.gov (United States)

    MacMartin, Douglas G.; Chanan, Gary A.

    2003-01-01

    The current design concept for the California Extremely Large Telescope (CELT) includes 1080 segments in the primary mirror, with the out-of-plane degrees of freedom actively controlled. We construct the control matrix for this active control system, and describe its singular modes and sensor noise propagation. Data from the Keck telescopes are used to generate realistic estimates of the control system contributions to the CELT wavefront error and wavefront gradient error. Based on these estimates, control system noise will not significantly degrade either seeing-limited or diffraction-limited observations. The use of supplemental wavefront information for real-time control is therefore not necessary. We also comment briefly on control system bandwidth requirements and limitations.

  14. Distributed Motor Controller (DMC) for Operation in Extreme Environments

    Science.gov (United States)

    McKinney, Colin M.; Yager, Jeremy A.; Mojarradi, Mohammad M.; Some, Rafi; Sirota, Allen; Kopf, Ted; Stern, Ryan; Hunter, Don

    2012-01-01

    This paper presents an extreme environment capable Distributed Motor Controller (DMC) module suitable for operation with a distributed architecture of future spacecraft systems. This motor controller is designed to be a bus-based electronics module capable of operating a single Brushless DC motor in extreme space environments: temperature (-120 C to +85 C required, -180 C to +100 C stretch goal); radiation (>;20K required, >;100KRad stretch goal); >;360 cycles of operation. Achieving this objective will result in a scalable modular configuration for motor control with enhanced reliability that will greatly lower cost during the design, fabrication and ATLO phases of future missions. Within the heart of the DMC lies a pair of cold-capable Application Specific Integrated Circuits (ASICs) and a Field Programmable Gate Array (FPGA) that enable its miniaturization and operation in extreme environments. The ASICs are fabricated in the IBM 0.5 micron Silicon Germanium (SiGe) BiCMOS process and are comprised of Analog circuitry to provide telemetry information, sensor interface, and health and status of DMC. The FPGA contains logic to provide motor control, status monitoring and spacecraft interface. The testing and characterization of these ASICs have yielded excellent functionality in cold temperatures (-135 C). The DMC module has demonstrated successful operation of a motor at temperature.

  15. Mortality in Extremely Low-Birth-Weight Neonates in México City (1985–2009

    Directory of Open Access Journals (Sweden)

    José Iglesias-Leboreiro

    2010-01-01

    Full Text Available Objective. To analyze 25 years of mortality of extremely low-birth-weight (ELBW neonates (≤1000 g in a private hospital in Mexico City and to establish the current viability limit for ELBW neonates. Methods. We designed a prospective observational study of all ELBW neonates born between 1985 and 2009. Neonatal mortality, early neonatal mortality, and the 120-day mortality rate were analyzed in 5-year intervals by two categories of birth weight (501–750 g and 751–1000 g. Results. Among the 50,823 total births, 158 were ELBW (3.1 per 103. Neonatal mortality (death ≤28 days decreased for the 501–750 g neonates from 88.9% (1985–1989 to 55.6% (2005–1999 (P=.008 and for 751–1000 g neonates also decreased from 50% to 5.3% (P=.002. The 120-day mortality for neonates over 500 g diminished: 501–750 g neonates, 88.9% to 61.1% (P=.02 and for 751–1000 g neonates, 62.5% to 15.8% (P=.002. The highest viability limit was established in neonates who weighed ≥650 g and were ≥26 weeks in gestational age. Conclusions. The survival of ELBW neonates has improved in Mexico particularly in private hospitals, and it was more evident over the years 2004–2009. These data suggest that it is possible to increase the ELBW neonates survive in developing counties.

  16. High incidence of rickets in extremely low birth weight infants with severe parenteral nutrition-associated cholestasis and bronchopulmonary dysplasia.

    Science.gov (United States)

    Lee, Soon Min; Namgung, Ran; Park, Min Soo; Eun, Ho Sun; Park, Kook In; Lee, Chul

    2012-12-01

    Risk factors for rickets of prematurity have not been re-examined since introduction of high mineral formula, particularly in ELBW infants. We analyzed the incidence and the risk factors of rickets in extremely low birth weight (ELBW) infants. As a retrospective case-control study from 2004 to 2008, risk factors were analyzed in 24 patients with rickets versus 31 patients without. The frequency of rickets in ELBW infants was 24/55 (44%). Infants with rickets were diagnosed at 48.2 ± 16.1 days of age, and improved by 85.3 ± 25.3 days. By radiologic evaluation, 29% were grade 1 rickets, 58% grade 2 and 13% grade 3. In univariate analysis, infants with rickets had significantly higher incidence of patent ductus arteriosus, parenteral nutrition associated cholestasis (PNAC), severe PNAC and moderate/severe bronchopulmonary dysplasia (BPD). In multiple regression analysis, after adjustment for gestation and birth weight, rickets significantly correlated with severe PNAC and with moderate/severe BPD. Serum peak alkaline phosphatase levels were significantly elevated in rickets (P rickets of prematurity remains high and the incidence of severe PNAC and moderate/severe BPD was significantly increased 18 and 3 times, respectively.

  17. Eating and weight control behaviors among middle school girls in relationship to body weight and ethnicity.

    Science.gov (United States)

    Shisslak, Catherine M; Mays, Mary Z; Crago, Marjorie; Jirsak, Jan K; Taitano, Keolani; Cagno, Colleen

    2006-05-01

    This study examined the links among body mass index (BMI), weight control practices, binge eating, and eating disorders in 1164 middle school girls. Both the prevalence and frequency of weight control behaviors increased as BMI increased, but binge eating was reported approximately equally by girls across the BMI spectrum.

  18. Reduced brachial flow-mediated vasodilation in young adult ex extremely low birth weight preterm: a condition predictive of increased cardiovascular risk?

    Science.gov (United States)

    Bassareo, P P; Fanos, V; Puddu, M; Demuru, P; Cadeddu, F; Balzarini, M; Mercuro, G

    2010-10-01

    Sporadic data present in literature report how preterm birth and low birth weight constitute the risk factors for the development of cardiovascular diseases in later life. To assess the presence of potential alterations to endothelial function in young adults born preterm at extremely low birth weight (Cesarea, Israel). Endothelial function was significantly reduced in ex-ELBW subjects compared to C (1.94 +/- 0.37 vs. 2.68 +/- 0.41, p < 0.0001). Moreover, this function correlated significantly with gestational age (r = 0.56, p < 0.0009) and birth weight (r = 0.63, p < 0.0001). The results obtained reveal a significant decrease in endothelial function of ex-ELBW subjects compared to controls, underlining a probable correlation with preterm birth and low birth weight. Taken together, these results suggest that an ELBW may underlie the onset of early circulatory dysfunction predictive of increased cardiovascular risk.

  19. Endogenous Generalized Weights under DEA Control

    DEFF Research Database (Denmark)

    Agrell, Per J.; Bogetoft, Peter

    Non-parametric efficiency analysis, such as Data Envelopment Analysis (DEA) relies so far on endogenous local or exogenous general weights, based on revealed preferences or market prices. However, as DEA is gaining popularity in regulation and normative budgeting, the strategic interest......, which also gives a more stable set of weights. The potential application could be to precipitate collective bargaining on cost efficiency for non-marketed resources and products. The models are applied to paneldata from 285 Danish district heating plants, where the open evaluation of multiple non...

  20. Gender and Socioeconomic Status in Relation to Weight Perception and Weight Control Behavior in Korean Adults

    Directory of Open Access Journals (Sweden)

    Hee-Kyung Joh

    2013-02-01

    Full Text Available Aim: In Korea, obesity is more prevalent among men and lower socioeconomic groups. To explain this obesity disparity, we compared weight perception and weight control behavior across gender and socioeconomic status (SES. Methods: We analyzed data from 16,260 participants aged 20 years or older in a nationally representative cross-sectional survey. SES indicators included education and income levels. Weight under-perception was defined when participants considered themselves lighter than their measured BMI status. Either no active or inappropriate weight control (i.e., trying to gain weight in obese individuals was considered to be unhealthy patterns. Multivariate prevalence ratios were calculated using log-binomial regressions. Results: Men had a higher prevalence of weight under-perception (24.5 vs. 11.9% and unhealthy patterns of weight control behavior (57 vs. 40% than women. Low education level was associated with weight under-perception (ptrend = 0.022 in men, ptrend trend trend = 0.047 in men, ptrend Conclusion: Weight perception and weight control behavior significantly varied by gender and SES. Public actions should be directed toward improving perception and behavior of high-risk populations.

  1. A hybrid joint based controller for an upper extremity exoskeleton

    Science.gov (United States)

    Mohd Khairuddin, Ismail; Taha, Zahari; Majeed, Anwar P. P. Abdul; Hakeem Deboucha, Abdel; Azraai Mohd Razman, Mohd; Aziz Jaafar, Abdul; Mohamed, Zulkifli

    2016-02-01

    This paper presents the modelling and control of a two degree of freedom upper extremity exoskeleton. The Euler-Lagrange formulation was used in deriving the dynamic modelling of both the human upper limb as well as the exoskeleton that consists of the upper arm and the forearm. The human model is based on anthropometrical measurements of the upper limb. The proportional-derivative (PD) computed torque control (CTC) architecture is employed in this study to investigate its efficacy performing joint-space control objectives specifically in rehabilitating the elbow and shoulder joints along the sagittal plane. An active force control (AFC) algorithm is also incorporated into the PD-CTC to investigate the effectiveness of this hybrid system in compensating disturbances. It was found that the AFC- PD-CTC performs well against the disturbances introduced into the system whilst achieving acceptable trajectory tracking as compared to the conventional PD-CTC control architecture.

  2. Weight Self-Regulation Process in Adolescence: The Relationship between Control Weight Attitudes, Behaviors, and Body Weight Status.

    Science.gov (United States)

    Pich, Jordi; Bibiloni, Maria Del Mar; Pons, Antoni; Tur, Josep A

    2015-01-01

    Adolescents' self-control weight behaviors were assessed (N = 1961; 12-17 years old; 2007-2008) in the Balearic Islands, Spain. The study analyzed the relationships between body weight status, body image, and self-weight concern, and actual attempts to lose weight by restrained eating and/or increased exercising. In terms of regulatory focus theory (RFT), we considered that efforts to lose or to maintain weight (successful or failed) would be motivated either by a "promotion focus" (to show an attractive body), or a "prevention focus" (to avoid social rejection of fatness), or both. Results showed that 41% of overweight boys and 25% of obese boys stated that they had never made any attempt to lose weight, and 13 and 4% in females. Around half of overweight boys and around a quarter of obese boys stated that they were "Not at all" concerned about weight gain, and girls' percentages decreased to 13 and 11%, respectively. By contrast, 57% of normal weight girls monitored their weight and stated that they had tried to become slim at least once. Weight self-regulation in females attempted to combine diet and exercise, while boys relied almost exclusively on exercise. Apparent lack of consciousness of body weight status among overweight boys, and more important, subsequent absence of behaviors to reduce their weight clearly challenges efforts to prevent obesity. We argue that several causes may be involved in this outcome, including unconscious, emotional (self-defense), and cognitive (dissonance) mechanisms driven by perceived social stigmatization of obesity. The active participation of social values of male and female body image (strong vs. pretty), and the existence of social habituation to overweight are suggested. A better knowledge of psychosocial mechanisms underlying adolescent weight self-control may improve obesity epidemics.

  3. Weight self-regulation process in adolescence: the relationship between control weight attitudes, behaviors and body weight status

    Directory of Open Access Journals (Sweden)

    Jordi ePich

    2015-05-01

    Full Text Available Adolescents’ self-control weight behaviors were assessed (n= 1961; 12-17 years old; 2007-2008 in the Balearic Islands, Spain. The study analyzed the relationships between body weight status, body image and self-weight concern, and actual attempts to lose weight by restrained eating and/or increased exercising. In terms of regulatory focus theory (RFT, we considered that efforts to lose or to maintain weight (successful or failed would be motivated either by a promotion focus (to show an attractive body, a prevention focus (to avoid social rejection of fatness, or both. Results showed that 41% of overweight boys and 25% of obese boys stated that they had never made any attempt to lose weight, and 13% and 4% in females. Around half of overweight boys and around a quarter of obese boys stated that they were Not at all concerned about weight gain, and girls’ percentages decreased to 13% and 11% respectively. By contrast 57% of normal weight girls monitored their weight and stated that they had tried to slim at least once. Weight self-regulation in females attempted to combine diet and exercise, while boys relied almost exclusively on exercise. Apparent lack of consciousness of body weight status among overweight boys, and more important, subsequent absence of behaviors to reduce their weight clearly challenges efforts to prevent obesity. We argue that several causes may be involved in this outcome, including unconscious emotional (self-defense and cognitive (dissonance mechanisms driven by perceived social stigmatization of obesity. The active participation of social values of male and female body image (strong vs. pretty and the existence of social habituation to overweight are suggested. A better knowledge of psychosocial mechanisms underlying adolescent weight self-control may improve obesity epidemics.

  4. Self-Regulation in Children Born with Extremely Low Birth Weight at 2 Years Old: A Comparison Study

    Science.gov (United States)

    Lynn, Lisa N.; Cuskelly, Monica; Gray, Peter H.; O'Callaghan, Michael J.

    2012-01-01

    Survival rates for children born with extremely low birth weight (ELBW) are increasing; however, many of these children experience later problems with learning. This study adopted an integrated approach to these problems, involving the self-regulatory tasks of inhibition and delay of gratification and relevant individual factors including…

  5. Frontal Electroencephalogram Asymmetry, Salivary Cortisol, and Internalizing Behavior Problems in Young Adults Who Were Born at Extremely Low Birth Weight

    Science.gov (United States)

    Schmidt, Louis A.; Miskovic, Vladimir; Boyle, Michael; Saigal, Saroj

    2010-01-01

    The authors examined internalizing behavior problems at middle childhood, adolescence, and young adulthood and brain-based measures of stress vulnerability in 154 right-handed, nonimpaired young adults (M age = 23 years): 71 (30 males, 41 females) born at extremely low birth weight (ELBW; less than 1,000 g) and 83 (35 males, 48 females) controls…

  6. Early corticosteroid treatment does not affect severity of unconjugated hyperbilirubinemia in extreme low birth weight preterm infants

    NARCIS (Netherlands)

    Hulzebos, Christian V.; Bos, Arend F.; Anttila, Eija; Hallman, Mikko; Verkade, Henkjan J.

    2011-01-01

    Aim: To determine the relationship between early postnatal dexamethasone (DXM) treatment and the severity of hyperbilirubinemia in extreme low birth weight (ELBW) preterm infants. Methods: In 54 ELBW preterm infants, total serum bilirubin concentrations (TSB) and phototherapy (PT) data during the fi

  7. The 'Effects of Transfusion Thresholds on Neurocognitive Outcome of Extremely Low Birth-Weight Infants (ETTNO)' Study

    DEFF Research Database (Denmark)

    Reinholdt, Jes; Veiergang, Gitte

    2012-01-01

    Background: Infants with extremely low birth weight uniformly develop anemia of prematurity and frequently require red blood cell transfusions (RBCTs). Although RBCT is widely practiced, the indications remain controversial in the absence of conclusive data on the long-term effects of RBCT...

  8. Overeating with and without loss of control: associations with weight status, weight-related characteristics, and psychosocial health

    Science.gov (United States)

    Goldschmidt, Andrea B.; Loth, Katie A.; MacLehose, Richard F.; Pisetsky, Emily M.; Berge, Jerica M.; Neumark-Sztainer, Dianne

    2015-01-01

    Objective The relative importance of loss of control and overeating in the relationship between binge eating and eating-related and general psychopathology has been debated in the literature. This study assessed the prevalence and correlates of overeating with and without loss of control within a diverse, population-based sample of adolescents. Method A highly diverse (81.1% non-White) sample of adolescents (n=2,793) from EAT-2010 (Eating and Activity in Teens) completed self-report questionnaires assessing eating-related psychopathology, substance use, non-suicidal self-injury, depressive symptoms, and self-esteem. Results Overeating without loss of control was reported by 6.9% of girls and 5.0% of boys, while 9.6% of girls and 6.3% of boys reported overeating with loss of control (binge eating). Overall, overeating (with or without loss of control) was positively associated with unhealthy or extreme weight control behaviors, dieting, non-suicidal self-injury, lower body satisfaction and self-esteem, and higher depressive symptoms relative to no overeating. Among girls, binge eating was associated with unhealthy or extreme weight control behaviors, lower self-esteem, and higher depressive symptoms relative to overeating without loss of control, while in boys, binge eating was associated with greater cigarette usage, lower body satisfaction, and greater depressive symptoms than overeating without loss of control (although cigarette usage was comparable in boys reporting binge eating and no overeating). Discussion Any overeating, with or without loss of control, was associated with multiple adverse correlates among adolescents. Loss of control was uniquely associated with multiple health indicators, further highlighting its importance as a marker of severity of overeating. PMID:26368333

  9. Investigating satiety for healthy weight : Appetite control

    NARCIS (Netherlands)

    Burgering, M.J.M.

    2013-01-01

    Modulating feelings of hunger and satiety could be a promising approach in weight management. TNO Food & Nutrition offers advanced assessment tools to support the development of food products that help address issues of overweight and underweight. This can reduce time, cost, and time-to-market.

  10. Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity

    Directory of Open Access Journals (Sweden)

    Kavaljit H. Chhabra

    2016-10-01

    Conclusions: Pomc reactivation in previously obese, calorie-restricted ArcPomc−/− mice normalized energy homeostasis, suggesting that their body weight set point was restored to control levels. In contrast, massively obese and hyperleptinemic ArcPomc−/− mice or those weight-matched and treated with PASylated leptin to maintain extreme hyperleptinemia prior to Pomc reactivation converged to an intermediate set point relative to lean control and obese ArcPomc−/− mice. We conclude that restoration of hypothalamic leptin sensitivity and Pomc expression is necessary for obese ArcPomc−/− mice to achieve and sustain normal metabolic homeostasis; whereas deficits in either parameter set a maladaptive allostatic balance that defends increased adiposity and body weight.

  11. Modelling and control of an upper extremity exoskeleton for rehabilitation

    Science.gov (United States)

    Taha, Zahari; Majeed, Anwar P. P. Abdul; Tze, Mohd Yashim Wong Paul; Abdo Hashem, Mohammed; Mohd Khairuddin, Ismail; Azraai Mohd Razman, Mohd

    2016-02-01

    This paper presents the modelling and control of a two degree of freedom upper extremity exoskeleton for rehabilitation. The Lagrangian formulation was employed to obtain the dynamic modelling of both the anthropometric based human upper limb as well as the exoskeleton that comprises of the upper arm and the forearm. A proportional-derivative (PD) architecture is employed to investigate its efficacy performing a joint task trajectory tracking in performing flexion/extension on the elbow joint as well as the forward adduction/abduction on the shoulder joint. An active force control (AFC) algorithm is also incorporated into the aforementioned controller to examine its effectiveness in compensating disturbances. It was found from the study that the AFC-PD performed well against the disturbances introduced into the system without compromising its tracking performances as compared to the conventional PD control architecture.

  12. Beyond bacteria: a study of the enteric microbial consortium in extremely low birth weight infants.

    Directory of Open Access Journals (Sweden)

    Mariam Susan LaTuga

    Full Text Available Extremely low birth weight (ELBW infants have high morbidity and mortality, frequently due to invasive infections from bacteria, fungi, and viruses. The microbial communities present in the gastrointestinal tracts of preterm infants may serve as a reservoir for invasive organisms and remain poorly characterized. We used deep pyrosequencing to examine the gut-associated microbiome of 11 ELBW infants in the first postnatal month, with a first time determination of the eukaryote microbiota such as fungi and nematodes, including bacteria and viruses that have not been previously described. Among the fungi observed, Candida sp. and Clavispora sp. dominated the sequences, but a range of environmental molds were also observed. Surprisingly, seventy-one percent of the infant fecal samples tested contained ribosomal sequences corresponding to the parasitic organism Trichinella. Ribosomal DNA sequences for the roundworm symbiont Xenorhabdus accompanied these sequences in the infant with the greatest proportion of Trichinella sequences. When examining ribosomal DNA sequences in aggregate, Enterobacteriales, Pseudomonas, Staphylococcus, and Enterococcus were the most abundant bacterial taxa in a low diversity bacterial community (mean Shannon-Weaver Index of 1.02 ± 0.69, with relatively little change within individual infants through time. To supplement the ribosomal sequence data, shotgun sequencing was performed on DNA from multiple displacement amplification (MDA of total fecal genomic DNA from two infants. In addition to the organisms mentioned previously, the metagenome also revealed sequences for gram positive and gram negative bacteriophages, as well as human adenovirus C. Together, these data reveal surprising eukaryotic and viral microbial diversity in ELBW enteric microbiota dominated bytypes of bacteria known to cause invasive disease in these infants.

  13. Natural products and body weight control

    Directory of Open Access Journals (Sweden)

    Jay Lee

    2011-01-01

    Full Text Available The purpose of the review was to summarise the effect of some commonly available natural products used for body weight management. We collected data from PubMed and scientific journals. There are numerous publications on this topic, however we have summarized the most commonly available and potent natural products from recent 53 publications. The natural products analyzed in this paper include catechins, capsaicin, conjugated linoleic acid, fucoxanthin, soy isoflavone, glabridin, astaxanthin and cyaniding-3-glucoside. These natural products are effective and safe for body weight management. Further studies need to be conducted to investigate the mechanism of action, metabolism, long term safety and side effects of these natural products, as well as interactions between these natural products with dietary components.

  14. Quasilinear Extreme Learning Machine Model Based Internal Model Control for Nonlinear Process

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    Dazi Li

    2015-01-01

    Full Text Available A new strategy for internal model control (IMC is proposed using a regression algorithm of quasilinear model with extreme learning machine (QL-ELM. Aimed at the chemical process with nonlinearity, the learning process of the internal model and inverse model is derived. The proposed QL-ELM is constructed as a linear ARX model with a complicated nonlinear coefficient. It shows some good approximation ability and fast convergence. The complicated coefficients are separated into two parts. The linear part is determined by recursive least square (RLS, while the nonlinear part is identified through extreme learning machine. The parameters of linear part and the output weights of ELM are estimated iteratively. The proposed internal model control is applied to CSTR process. The effectiveness and accuracy of the proposed method are extensively verified through numerical results.

  15. The Relationship between Smoking and Unhealthy Weight Control Behaviors among Korean Adolescents: The Tenth Korea Youth Risk Behavior Web-Based Survey, 2014

    Science.gov (United States)

    Sim, Won Yong; Kang, Jae Heon; Park, Hyun Ah; Kim, Kyoung Woo; Hur, Yang Im; Shin, Koh Eun; Byeon, Gyeong Ran

    2017-01-01

    Background Adolescent smoking is positively related to weight control attempts, especially by unhealthy methods. The co-occurrence of smoking and unhealthy weight control behaviors may cause serious health problems in adolescents. This study examined the relationship of smoking with unhealthy weight control behaviors among Korean adolescents. Methods This cross-sectional study involved 31,090 students of grades 7 to 12, who had tried to reduce or maintain their weight during the 30 days prior to The Tenth Korea Youth Risk Behavior Web-based Survey, 2014. Data on height, weight, weight control methods, smoking, alcohol intake, living with one's family, and perceived economic status were obtained through self-report questionnaires. ‘Unhealthy weight control behaviors’ were subcategorized into ‘extreme weight control behaviors’ and ‘less extreme weight control behaviors.’ Results The smoking rates were 13.3%±0.4% in boys and 3.8%±0.2% in girls. Current smokers were more likely to engage in extreme weight control behaviors (odds ratio [OR], 1.47; 95% confidence interval [CI], 1.09 to 2.00 in boys, and OR, 2.05; 95% CI, 1.59 to 2.65 in girls) and less extreme weight control behaviors (OR, 1.23; 95% CI, 1.07 to 1.40 in boys, and OR, 1.47; 95% CI, 1.22 to 1.76 in girls) compared to non-smokers among both boys and girls. Conclusion Current smoking is independently related to a high likelihood of engaging in unhealthy weight control behaviors among Korean adolescents. This relationship is stronger for girls than for boys. Extreme weight control behaviors have a stronger relationship with current smoking than less extreme weight control behaviors. PMID:28197330

  16. Motivation, self-determination, and long-term weight control

    Directory of Open Access Journals (Sweden)

    Teixeira Pedro J

    2012-03-01

    Full Text Available Abstract This article explores the topics of motivation and self-regulation in the context of weight management and related behaviors. We focus on the role of a qualitative approach to address motivation - not only considering the level but also type of motivation - in weight control and related behaviors. We critically discuss the operationalization of motivation in current weight control programs, present a complementary approach to understanding motivation based on self-determination theory, and review empirical findings from weight control studies that have used self-determination theory measures and assessed their association with weight outcomes. Weight loss studies which used Motivational Interviewing (MI are also reviewed, considering MI's focus on enhancing internal motivation. We hypothesize that current weight control interventions may have been less successful with weight maintenance in part due to their relative disregard of qualitative dimensions of motivation, such as level of perceived autonomy, often resulting in a motivational disconnect between weight loss and weight-related behaviors. We suggest that if individuals fully endorse weight loss-related behavioral goals and feel not just competent but also autonomous about reaching them, as suggested by self-determination theory, their efforts are more likely to result in long-lasting behavior change.

  17. Motivation, self-determination, and long-term weight control

    Science.gov (United States)

    2012-01-01

    This article explores the topics of motivation and self-regulation in the context of weight management and related behaviors. We focus on the role of a qualitative approach to address motivation - not only considering the level but also type of motivation - in weight control and related behaviors. We critically discuss the operationalization of motivation in current weight control programs, present a complementary approach to understanding motivation based on self-determination theory, and review empirical findings from weight control studies that have used self-determination theory measures and assessed their association with weight outcomes. Weight loss studies which used Motivational Interviewing (MI) are also reviewed, considering MI's focus on enhancing internal motivation. We hypothesize that current weight control interventions may have been less successful with weight maintenance in part due to their relative disregard of qualitative dimensions of motivation, such as level of perceived autonomy, often resulting in a motivational disconnect between weight loss and weight-related behaviors. We suggest that if individuals fully endorse weight loss-related behavioral goals and feel not just competent but also autonomous about reaching them, as suggested by self-determination theory, their efforts are more likely to result in long-lasting behavior change. PMID:22385818

  18. Optimizing weight control in diabetes: antidiabetic drug selection

    Directory of Open Access Journals (Sweden)

    S Kalra

    2010-08-01

    Full Text Available S Kalra1, B Kalra1, AG Unnikrishnan2, N Agrawal3, S Kumar41Bharti Hospital, Karnal; 2Amrita Institute of Medical Science, Kochi; 3Medical College, Gwalior; 4Excel Life Sciences, Noida, IndiaDate of preparation: 18th August 2010Conflict of interest: SK has received speaker fees from Novo Nordisk, sanofi-aventis, MSD, Eli Lilly, BMS, and AstraZeneca.Clinical question: Which antidiabetic drugs provide optimal weight control in patients with type 2 diabetes?Results: Metformin reduces weight gain, and may cause weight loss, when given alone or in combination with other drugs. Pioglitazone and rosiglitazone use is associated with weight gain. Use of the glucagon-like peptide-1 (GLP-1 analogs, liraglutide and exenatide, is associated with weight loss. Dipeptidyl peptidase-4 (DPP-4 inhibitors are considered weight-neutral. Results with insulin therapy are conflicting. Insulin detemir provides weight control along with glycemic control.Implementation: • Weight gain is considered an inevitable part of good glycemic control using conventional modalities of treatment such as sulfonylureas.• Use of metformin, weight-sparing insulin analogs such as insulin detemir, and liraglutide, should be encouraged as monotherapy, or in combination with other drugs.Keywords: weight control, diabetes

  19. Family Food Choices: A Guide to Weight and Diabetes Control.

    Science.gov (United States)

    Indian Health Service (PHS/HSA), Rockville, MD.

    Written for American Indians who have diabetes, this folder explains diabetes and outlines a weight control program and diet. The folder discusses the five things diabetics can do to help control their disease: lose weight, watch the amount and kind of fat eaten, eat more food with fiber, avoid sugar, and avoid alcohol. Charts for foods containing…

  20. Genetic susceptibility testing and readiness to control weight: Results from a randomized controlled trial

    NARCIS (Netherlands)

    Meisel, S.F.; Beeken, R.J.; Jaarsveld, C.H.M. van; Wardle, J.

    2015-01-01

    OBJECTIVE: To test the hypothesis that adding obesity gene feedback (FTO) to simple weight control advice at a life stage with raised risk of weight gain (university) increases readiness to control weight. METHODS: Individually randomized controlled trial comparing the effect of: (i) simple weight c

  1. Chronic lower extremity lymphedema: A comparative study of high-resolution interstitial MR lymphangiography and heavily T2-weighted MRI

    Energy Technology Data Exchange (ETDEWEB)

    Lu Qing [Department of Radiology, Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine, 1630 Dong Fang Rd, Shanghai 200127 (China)], E-mail: luqingshan@sjtu.edu.cn; Xu Jianrong [Department of Radiology, Shanghai Renji Hospital, Shanghai Jiao Tong University School of Medicine, 1630 Dong Fang Rd, Shanghai 200127 (China)], E-mail: jiangrongx@hotmail.com; Liu Ningfei [Department of Plastic and Reconstructive Surgery, Shanghai 9th People' s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai Second Medical University, 639 Zhi Zao Ju Rd, Shanghai 200011 (China)], E-mail: luqing_1973@163.com

    2010-02-15

    Purpose: To assess the role of heavily T2-weighted image and interstitial MR lymphangiography (MRL) for the visualization of lymphatic vessels in patients with disorders of the lymphatic circulation. Methods: Forty lower extremities in 31 patients (9 bilateral and 22 unilateral) with primary lymphedema were examined by heavily T2-weighted image and indirect MRL. Maximum-intensity projection (MIP) was used to reconstruct the images of the lymphatic system. Two experienced radiologists analyzed the images with regard to the differences in image quality, number of lymphatic vessels, its maximum diameter and two other findings: accumulated lymph fluid in the tissue and honeycombing pattern. Results: The beaded appearance of the affected vessels in 73 leg segments of 40 lower extremities were present on both modalities 3D MIP. Larger amount of the dilated lymphatic vessels were visualized on heavily T2-weighted image than that on MRL (p = 0.003) and the maximum diameter of it was 4.28 {+-} 1.53 mm on heavily T2-weighted image, whereas 3.41 {+-} 1.05 mm on MRL (p < 0.01). The dilated lymphatic vessels on MRL showed better image quality and greater SNR and CNR than that on heavily T2-weighted image (p < 0.01). The regions of accumulated lymph fluid and the honeycombing pattern extent were identified on heavily T2-weighted image scored statistically higher than that on MRL (p < 0.01). Conclusion: The heavily T2-weighted imaging has greater sensitivity and the MRL image has higher legibility for detecting the pathologically modified lymphatic vessels and accompanying complications non-invasively. Combining these two MR techniques can accurately access the pathological changes in the lower extremity with lymphedema.

  2. Body Weight Perception, Unhealthy Weight Control Behaviors, and Suicidal Ideation among Korean Adolescents

    Science.gov (United States)

    Kim, Dong-Sik; Cho, Youngtae; Cho, Sung-Il; Lim, In-Sook

    2009-01-01

    Background: This study examined the mediating function of body weight perception (BWP) in the relation between body mass index (BMI) and unhealthy weight control behaviors (UWCBs; eg, fasting, using diet pills, or laxatives), and between BMI and suicidal ideation. It also explored the correlation between exposure to multiple UWCBs and suicidal…

  3. The bid to lose weight: impact of social media on weight perceptions, weight control and diabetes.

    Science.gov (United States)

    Das, Leah; Mohan, Ranjini; Makaya, Tafadzwa

    2014-01-01

    Over the last decade the internet has come to permeate every aspect of our lives. With huge leaps in accessibility of the internet via mobile personal devices such as smart cellular phones and tablets, individuals are connected to the internet virtually all the time. It is no surprise therefore that social media now dominates the lives of many people within society. The authors take a look at how social media is influencing diabetes with particular focus on weight perception, weight management and eating behaviours. The authors explore the concept of how the advertising of Size 0 models and photo-shopping of images which are easily available on line and via social media is causing an increase in the number of young people with distorted body images. This has led to an increased number of people resorting to sometimes drastic weight loss programmes. We focus on the bid for 'low-fat' consumption and highlight how this could actually be leading to an increased risk for developing diabetes or worsening the complications of diabetes. We also discuss the increase of eating disorder in diabetes related to this distorted body image.

  4. Daily Self-Weighing to Control Body Weight in Adults

    Directory of Open Access Journals (Sweden)

    Carly R. Pacanowski

    2014-12-01

    Full Text Available The objective of this study is to review the history of daily self-weighing for weight control, discuss the possibility that self-weighing may cause adverse psychological symptoms, and propose mechanisms that explain how self-weighing facilitates weight control. A systematic forward (citation tracking approach has been employed in this study. In the early literature, experimental tests did not demonstrate a benefit of adding daily self-weighing to traditional behavioral modification for weight loss. More recent studies have shown that daily self-weighing combined with personalized electronic feedback can produce and sustain weight loss with and without a traditional weight loss program. Daily self-weighing appears to be effective in preventing age-related weight gain. Apart from these experimental findings, there is considerable agreement that the frequency of self-weighing correlates with success in losing weight and sustaining the weight loss. The early literature suggested frequent self-weighing may be associated with negative psychological effects. However, more recent experimental trials do not substantiate such a causal relationship. In conclusion, daily self-weighing may be a useful strategy for certain adults to prevent weight gain, lose weight, or prevent weight regain after loss. More research is needed to better understand the role of different types of feedback, who benefits most from self-weighing, and at what frequency.

  5. Lack of Melanopsin Is Associated with Extreme Weight Loss in Mice upon Dietary Challenge.

    Directory of Open Access Journals (Sweden)

    Didem Göz Aytürk

    Full Text Available Metabolic disorders have been established as major risk factors for ocular complications and poor vision. However, little is known about the inverse possibility that ocular disease may cause metabolic dysfunction. To test this hypothesis, we assessed the metabolic consequences of a robust dietary challenge in several mouse models suffering from retinal mutations. To this end, mice null for melanopsin (Opn4-/-, the photopigment of intrinsically photosensitive retinal ganglion cells (ipRGCs, were subjected to five weeks of a ketogenic diet. These mice lost significantly more weight than wild-type controls or mice lacking rod and cone photoreceptors (Pde6brd1/rd1. Although ipRGCs are critical for proper circadian entrainment, and circadian misalignment has been implicated in metabolic pathology, we observed no differences in entrainment between Opn4-/- and control mice. Additionally, we observed no differences in any tested metabolic parameter between these mouse strains. Further studies are required to establish the mechanism giving rise to this dramatic phenotype observed in melanopsin-null mice. We conclude that the causality between ocular disease and metabolic disorders merits further investigation due to the popularity of diets that rely on the induction of a ketogenic state. Our study is a first step toward understanding retinal pathology as a potential cause of metabolic dysfunction.

  6. Reprogramming the body weight set point by a reciprocal interaction of hypothalamic leptin sensitivity and Pomc gene expression reverts extreme obesity.

    Science.gov (United States)

    Chhabra, Kavaljit H; Adams, Jessica M; Jones, Graham L; Yamashita, Miho; Schlapschy, Martin; Skerra, Arne; Rubinstein, Marcelo; Low, Malcolm J

    2016-10-01

    A major challenge for obesity treatment is the maintenance of reduced body weight. Diet-induced obese mice are resistant to achieving normoweight once the obesogenic conditions are reversed, in part because lowered circulating leptin leads to a reduction in metabolic rate and a rebound of hyperphagia that defend the previously elevated body weight set point. Because hypothalamic POMC is a central leptin target, we investigated whether changes in circulating leptin modify Pomc expression to maintain normal energy balance in genetically predisposed obese mice. Mice with reversible Pomc silencing in the arcuate nucleus (ArcPomc (-/-)) become morbidly obese eating low-fat chow. We measured body composition, food intake, plasma leptin, and leptin sensitivity in ArcPomc (-/-) mice weight-matched to littermate controls by calorie restriction, either from weaning or after developing obesity. Pomc was reactivated by tamoxifen-dependent Cre recombinase transgenes. Long acting PASylated leptin was administered to weight-reduced ArcPomc (-/-) mice to mimic the super-elevated leptin levels of obese mice. ArcPomc (-/-) mice had increased adiposity and leptin levels shortly after weaning. Despite chronic calorie restriction to achieve normoweight, ArcPomc (-/-) mice remained moderately hyperleptinemic and resistant to exogenous leptin's effects to reduce weight and food intake. However, subsequent Pomc reactivation in weight-matched ArcPomc (-/-) mice normalized plasma leptin, leptin sensitivity, adiposity, and food intake. In contrast, extreme hyperleptinemia induced by PASylated leptin blocked the full restoration of hypothalamic Pomc expression in calorie restricted ArcPomc (-/-) mice, which consequently regained 30% of their lost body weight and attained a metabolic steady state similar to that of tamoxifen treated obese ArcPomc (-/-) mice. Pomc reactivation in previously obese, calorie-restricted ArcPomc (-/-) mice normalized energy homeostasis, suggesting that their body

  7. Health literacy and parent attitudes about weight control for children.

    Science.gov (United States)

    Liechty, Janet M; Saltzman, Jaclyn A; Musaad, Salma M

    2015-08-01

    The purpose of this study was to examine associations between parental health literacy and parent attitudes about weight control strategies for young children. Parental low health literacy has been associated with poor child health outcomes, yet little is known about its relationship to child weight control and weight-related health information-seeking preferences. Data were drawn from the STRONG Kids Study, a Midwest panel survey among parents of preschool aged children (n = 497). Parents endorsed an average of 4.3 (SD =2.8) weight loss strategies, 53% endorsed all three recommended weight loss strategies for children, and fewer than 1% of parents endorsed any unsafe strategies. Parents were most likely to seek child weight loss information from healthcare professionals but those with low (vs. adequate) health literacy were significantly less likely to use the Internet or books and more likely to use minister/clergy as sources. Poisson and logistic regressions showed that higher health literacy was associated with endorsement of more strategies overall, more recommended strategies, and greater odds of endorsing each specific recommended strategy for child weight control, after adjusting for parent age, education, race/ethnicity, income, marital status, weight concern, and child BMI percentile. Findings suggest that health literacy impacts parental views about child weight loss strategies and health information-seeking preferences. Pediatric weight loss advice to parents should include assessment of parent attitudes and prior knowledge about child weight control and facilitate parent access to reliable sources of evidence-informed child weight control information.

  8. Controlled free-induction decay in the extreme ultraviolet

    CERN Document Server

    Bengtsson, Samuel; Kroon, David; Camp, Seth; Miranda, Miguel; Arnold, Cord L; L'Huillier, Anne; Schafer, Kenneth J; Gaarde, Mette B; Rippe, Lars; Mauritsson, Johan

    2016-01-01

    Coherent sources of attosecond extreme ultraviolet (XUV) radiation present many challenges if their full potential is to be realized. While many applications benefit from the broadband nature of these sources, it is also desirable to produce narrow band XUV pulses, or to study autoionizing resonances in a manner that is free of the broad ionization background that accompanies above-threshold XUV excitation. Here we demonstrate a method for controlling the coherent XUV free induction decay that results from using attosecond pulses to excite a gas, yielding a fully functional modulator for XUV wavelengths. We use an infrared (IR) control pulse to manipulate both the spatial and spectral phase of the XUV emission, sending the light in a direction of our choosing at a time of our choosing. This allows us to tailor the light using opto-optical modulation, similar to devices available in the IR and visible wavelength regions.

  9. Extreme Rapid Weight Loss and Rapid Weight Gain Observed in UK Mixed Martial Arts Athletes Preparing for Competition.

    Science.gov (United States)

    Matthews, Joseph John; Nicholas, Ceri

    2016-10-06

    There is a lack of research documenting the weight-making practices of mixed-martial-arts (MMA) competitors. The purpose of the investigation was to quantify the magnitude and identify the methods of rapid weight loss (RWL) and rapid weight gain (RWG) in MMA athletes preparing for competition. Seven athletes (mean ± SD, age 24.6 ± 3.5 yrs, body mass 69.9 ± 5.7 kg, competitive experience 3.1 ± 2.2 yrs) participated in a repeated-measures design. Measures of dietary intake, urinary hydration status, and body mass were recorded in the week preceding competition. Body mass decreased significantly (p<0.0005) from baseline by 5.6 ± 1.4 kg (8 ± 1.8%). During the RWG period (32 ± 1 hours) body mass increased significantly (p<0.001) by 7.4 ± 2.8 kg (11.7 ± 4.7%), exceeding RWL. Mean energy and carbohydrate intake were 3176 ± 482 kcal·day(-1) and 471 ± 124 g·day(-1), respectively. At the official weigh-in 57% of athletes were dehydrated (1033 ± 19 mOsmol·kg(-1)) and the remaining 43% were severely dehydrated (1267 ± 47 mOsmol·kg(-1)). Athletes reported using harmful dehydration-based RWL strategies, including sauna (43%) and training in plastic suits (43%). Results demonstrated RWG greater than RWL, this is a novel finding and may be attributable to the 32 hour duration from weigh-in till competition. The observed magnitude of RWL and strategies used are comparable to those which have previously resulted in fatalities. Rule changes which make RWL impractical should be implemented with immediate effect to ensure the health, safety and wellbeing of competitors.

  10. Extreme Precision Environmental Control for Next Generation Radial Velocity Spectrographs

    Science.gov (United States)

    Stefansson, Gudmundur K.; Hearty, Fred; Levi, Eric; Robertson, Paul; Mahadevan, Suvrath; Bender, Chad; Nelson, Matt; Halverson, Samuel

    2015-12-01

    Extreme radial velocity precisions of order 10cm/s will enable the discoveries of Earth-like planets around solar-type stars. Temperature and pressure variations inside a spectrograph can lead to thermomechanical instabilities in the optics and mounts, and refractive index variations in both the optical elements as well as the surrounding air. Together, these variations can easily induce instrumental drifts of several tens to hundreds of meters per second. Enclosing the full optical train in thermally stabilized high-vacuum environments minimizes such errors. In this talk, I will discuss the Environmental Control System (ECS) for the Habitable Zone Planet Finder (HPF) spectrograph: a near infrared (NIR) facility class instrument we will commission at the Hobby Eberly Telescope in 2016. The ECS will maintain the HPF optical bench stable at 180K at the sub milli-Kelvin level on the timescale of days, and at the few milli-Kelvin level over months to years. The entire spectrograph is kept under high-quality vacuum (compensated for with an actively controlled radiation shield outfitted with custom feedback electronics. High efficiency Multi-Layer Insulation (MLI) blankets, and a passive external thermal enclosure further isolate the optics from ambient perturbations. This environmental control scheme is versatile, suitable to stabilize both next generation NIR, and optical spectrographs. I will show how we are currently testing this control system for use with our design concept of the Extreme Precision Doppler Spectrograph (EPDS), the next generation optical spectrograph for the WIYN 3.5m telescope. Our most recent results from full-scale stability tests will be presented.

  11. Probabilistic solution of relative entropy weighted control

    CERN Document Server

    Bierkens, Joris

    2012-01-01

    We show that stochastic control problems with a particular cost structure involving a relative entropy term admit a purely probabilistic solution, without the necessity of applying the dynamic programming principle. The argument is as follows. Minimization of the expectation of a random variable with respect to the underlying probability measure, penalized by relative entropy, may be solved exactly. In the case where the randomness is generated by a standard Brownian motion, this exact solution can be written as a Girsanov density. The stochastic process appearing in the Girsanov exponent has the role of control process, and the relative entropy of the change of probability measure is equal to the integral of the square of this process. An explicit expression for the control process may be obtained in terms of the Malliavin derivative of the density process. The theory is applied to the problem of minimizing the maximum of a Brownian motion (penalized by the relative entropy), leading to an explicit expressio...

  12. The effect of segmental weight of prosthesis on hemodynamic responses and energy expenditure of lower extremity amputees

    OpenAIRE

    Mutlu, Akmer; Kharooty, Mohammad Dawood; Yakut, Yavuz

    2017-01-01

    [Purpose] The aim of this study was to investigate the effect of segmental weight of the prosthesis on hemodynamic responses and energy expenditure in lower extremity amputees. [Subjects and Methods] Thirteen patients with a mean age of 44 ± 15.84 years and with unilateral transtibial, transfemoral and Syme’s amputation were included to the study. The difference between the lightest and the heaviest prosthesis, 250 g used as the weight. All the patients completed the measurements first withou...

  13. Sidelobe Suppression with Null Steering by Independent Weight Control

    Directory of Open Access Journals (Sweden)

    Zafar-Ullah Khan

    2015-01-01

    Full Text Available A uniform linear array of n antenna elements can steer up to n-1 nulls. In situations where less than n-1 nulls are required to be steered, the existing algorithms have no criterion to utilize the remaining weights for sidelobe suppression. This work combines sidelobe suppression capability with null steering by independent weight control. For this purpose, the array factor is transformed as the product of two polynomials. One of the polynomials is used for null steering by independent weight control, while the second one is for sidelobe suppression whose coefficients or weights are determined by using convex optimization. Finally, a new structure is proposed to incorporate the product of two polynomials such that sidelobe suppression weights are decoupled from those of null steering weights. Simulation results validate the effectiveness of the proposed scheme.

  14. Extreme Temperatures May Increase Risk for Low Birth Weight at Term

    Science.gov (United States)

    ... at term, NIH study suggests Skip sharing on social media links Share this: Page Content Monday, February 27, 201 7 -Stock photo Extreme hot or cold temperatures during pregnancy may increase the risk that infants born at ...

  15. Weight Gain Through Self-Control Procedures

    Science.gov (United States)

    Gulanick, Nancy; And Others

    1975-01-01

    Underweight subjects were assigned to either a self-reinforcement condition, a self-punishment condition, or to a discussion/reflection control condition. The subjects received one treatment session per week over a five-week period. After treatment, the self-reinforcement groups gained significantly more pounds (kilograms) than either of the other…

  16. Control of Body Weight by Eating Behavior in Children

    OpenAIRE

    2015-01-01

    Diet, exercise, and pharmacological interventions have limited effects in counteracting the worldwide increase in pediatric body weight. Moreover, the promise that individualized drug design will work to induce weight loss appears to be exaggerated. We suggest that the reason for this limited success is that the cause of obesity has been misunderstood. Body weight is mainly under external control; our brain permits us to eat under most circumstances, and unless the financial or physical cost ...

  17. The effect of segmental weight of prosthesis on hemodynamic responses and energy expenditure of lower extremity amputees.

    Science.gov (United States)

    Mutlu, Akmer; Kharooty, Mohammad Dawood; Yakut, Yavuz

    2017-04-01

    [Purpose] The aim of this study was to investigate the effect of segmental weight of the prosthesis on hemodynamic responses and energy expenditure in lower extremity amputees. [Subjects and Methods] Thirteen patients with a mean age of 44 ± 15.84 years and with unilateral transtibial, transfemoral and Syme's amputation were included to the study. The difference between the lightest and the heaviest prosthesis, 250 g used as the weight. All the patients completed the measurements first without weight and then with 250 g weight on the ankle joint. The blood pressure and heart rate of the patients were recorded before and after Six Minute Walk Test (6MWT) and 10 stairs up & down stairs test. Physiological Cost Index was used to calculate the energy expenditure. [Results] Heart rate and energy expenditure increased significantly when without weight and with weight results compared. [Conclusion] We conclude that the segmental weight of the prosthetic limb has a significant effect on the heart rate and energy expenditure but has no effect on the systolic and diastolic blood pressure of lower limb amputees. In order to generalize our results to lower limb amputees, more patients need to be included in future studies.

  18. Control of body weight by eating behavior in children

    Directory of Open Access Journals (Sweden)

    Modjtaba eZandian

    2015-10-01

    Full Text Available Diet, exercise, and pharmacological interventions have limited effects in counteracting the worldwide increase in pediatric body weight. Moreover, the promise that individualized drug design will work to induce weight loss appears to be exaggerated. We suggest that the reason for this limited success is that the cause of obesity has been misunderstood. Body weight is mainly under external control; our brain permits us to eat under most circumstances, and unless the financial or physical cost of food is high, eating and body weight increase by default. When energy-rich, inexpensive foods are continually available, people need external support to maintain a healthy body weight. Weight loss can thereby be achieved by continuous feedback on how much and how fast to eat on a computer screen.

  19. Factors affecting prenatal sonographic estimation of weight in extremely low birthweight infants.

    Science.gov (United States)

    Townsend, R R; Filly, R A; Callen, P W; Laros, R K

    1988-04-01

    Because critical management decisions are based on sonographic estimation of fetal weight in fetuses less than 1000 g, we sought to evaluate the accuracy of birthweight prediction in this range and to identify factors affecting this accuracy. Fetal weight was estimated using several published methods in 53 fetuses with birthweights less than 1000 g. Standard deviations greater than 12.3% indicate more random error in the sonographic weight prediction than has been reported in higher weight groups. No statistically significant differences were found between patient groups with decreased, normal, or increased amniotic fluid volume or portable examination. There was a trend toward lower mean deviation (2.9 vs 6.0%) and standard deviation (8.9 vs. 15.0%) in studies with scan quality judged "good" compared with "poor" based on ability to visualize anatomic landmarks.

  20. Frequency weighted system identification and linear quadratic controller design

    Science.gov (United States)

    Horta, Lucas G.; Phan, Minh; Juang, Jer-Nan; Longman, Richard W.; Sulla, Jeffrey L.

    1991-01-01

    Application of filters for frequency weighting of Markov parameters (pulse response functions) is described in relation to system/observer identification. The time domain identification approach recovers a model which has a pulse response weighted according to frequency. The identified model is composed of the original system and filters. The augmented system is in a form which can be used directly for frequency weighted linear quadratic controller design. Data from either single or multiple experiments can be used to recover the Markov parameters. Measured acceleration signals from a truss structure are used for system identification and the model obtained is used for frequency weighted controller design. The procedure makes the identification and controler design complementary problems.

  1. Bariatric surgery-induced weight loss causes remission of food addiction in extreme obesity.

    Science.gov (United States)

    Pepino, Marta Yanina; Stein, Richard I; Eagon, J Christopher; Klein, Samuel

    2014-08-01

    To test the hypotheses that bariatric surgery-induced weight loss: induces remission of food addiction (FA), and normalizes other eating behaviors associated with FA. Forty-four obese subjects (BMI= 48 ± 8 kg/m(2) ) were studied before and after ∼20% weight loss induced by bariatric surgery (25 Roux-en-Y gastric bypass, 11 laparoscopic adjustable gastric banding, and eight sleeve gastrectomy). We assessed: FA (Yale Food Addiction Scale), food cravings (Food Craving Inventory), and restrictive, emotional and external eating behaviors (Dutch Eating Behavior Questionnaire). FA was identified in 32% of subjects before surgery. Compared with non-FA subjects, those with FA craved foods more frequently, and had higher scores for emotional and external eating behaviors (all P-values 0.8). Surgery-induced weight loss resulted in remission of FA in 93% of FA subjects; no new cases of FA developed after surgery. Surgery-induced weight loss decreased food cravings, and emotional and external eating behaviors in both groups (all P-values 1.1). Bariatric surgery-induced weight loss induces remission of FA and improves several eating behaviors that are associated with FA. Copyright © 2014 The Obesity Society.

  2. Potential Mechanisms of Cancer Prevention by Weight Control

    Science.gov (United States)

    Jiang, Yu; Wang, Weiqun

    Weight control via dietary caloric restriction and/or physical activity has been demonstrated in animal models for cancer prevention. However, the underlying mechanisms are not fully understood. Body weight loss due to negative energy balance significantly reduces some metabolic growth factors and endocrinal hormones such as IGF-1, leptin, and adiponectin, but enhances glucocorticoids, that may be associated with anti-cancer mechanisms. In this review, we summarized the recent studies related to weight control and growth factors. The potential molecular targets focused on those growth factors- and hormones-dependent cellular signaling pathways are further discussed. It appears that multiple factors and multiple signaling cascades, especially for Ras-MAPK-proliferation and PI3K-Akt-anti-apoptosis, could be involved in response to weight change by dietary calorie restriction and/or exercise training. Considering prevalence of obesity or overweight that becomes apparent over the world, understanding the underlying mechanisms among weight control, endocrine change and cancer risk is critically important. Future studies using "-omics" technologies will be warrant for a broader and deeper mechanistic information regarding cancer prevention by weight control.

  3. Teasing and weight-control behaviors in adolescent girls

    Directory of Open Access Journals (Sweden)

    Ana Carolina B. Leme

    2013-12-01

    Full Text Available OBJECTIVE: To analyze the association between weight teasing, body satisfaction and weight control behaviors. METHODS: Cross-sectional study based on adaptation and validity research of a North American questionnaire for adolescent girls about physical activity, nutrition, body image, perceptions, and behaviors. The variables used to conduct the study were weight control behaviors, body satisfaction and presence of teasing by family members. Descriptive analyses were carried out by chi-square test, being significant p<0.05. RESULTS: A total of 159 adolescent girls, with 16.2±1.3 years old were enrolled in this study. Of the total, 60.1% reported that family members did not tease them. The teasing was associated with weight dissatisfaction (p<0.001, body shape (p=0.006, belly (p=0.001, waist (p=0.001, face (p=0.009, arms (p=0.014 and shoulders (p=0.001. As a consequence, there was association with unhealthy weight control behaviors (p<0.001, vomiting (p=0,011, diet (p=0.002 and use of laxatives (p=0.035. CONCLUSIONS: The teasing about body image by family members was associated with risk for unhealthy weight control behaviors in female adolescents.

  4. Criminal Control and Evaluation of Extreme Nationalist Terrorist Crime

    Institute of Scientific and Technical Information of China (English)

    Ran Hui

    2017-01-01

    After entering the 21st century, ter ̄rorist crimes have become more serious. Terrorism has become one of the worst problems of the mod ̄ern world and will continue to be a serious problem in the future. China is also facing the challenge of terrorist crime. Can the present criminal system accomplish the mission of legislative control of these crimes and fulfill the goal of penalising them? It seems that a review and evaluation of the rele ̄vant criminal legislation and policies is necessary. There are different definitions of terrorist crimes. American scholars Alex P. Schmid and Albert J. Jongman gave a review of 109 different definitions that appeared during the period from 1936 to 1983 , and proposed their own opinions in the book Political Terrorism. Chinese scholar Hu Lianhe analyzed 50 definitions that appeared after 1982, and proposed his own idea. On January 1 2016 , the third article of the Zhonghua renmin gongheguo fan kongbu zhuyi fa ( Anti -terrorism Law of the P. R. C) formally defines “terrorism”and “terrorist activities”. Generally speaking, both the academic and legal definitions have gener ̄alized three characteristics of “terrorist crime”from subjective and objective aspects: 1 ) taking social order, public security, personnel and prop ̄erty as the target of the ( terrorist ) behavior; 2 ) hurting the targets described above or threatening the state organs or international organizations by way of violence, destruction or intimidation; 3 ) taking the realization of some certain political or i ̄deological purpose and claims as the ultimate goal of the ( terrorist) behavior. Concerning the relation between extreme na ̄tionalism and terrorism, the general idea is that“there is no pure form of nationalism; it is always combined with some certain political or social pow ̄er, and characterized with social movement or his ̄torical process”. And seeing from the development course of terrorism,“nationalism is one of the most

  5. Fault Tolerance Automotive Air-Ratio Control Using Extreme Learning Machine Model Predictive Controller

    OpenAIRE

    Pak Kin Wong; Hang Cheong Wong; Chi Man Vong; Tong Meng Iong; Ka In Wong; Xianghui Gao

    2015-01-01

    Effective air-ratio control is desirable to maintain the best engine performance. However, traditional air-ratio control assumes the lambda sensor located at the tail pipe works properly and relies strongly on the air-ratio feedback signal measured by the lambda sensor. When the sensor is warming up during cold start or under failure, the traditional air-ratio control no longer works. To address this issue, this paper utilizes an advanced modelling technique, kernel extreme learning machine (...

  6. Effectiveness-weighted control method for a cooling system

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Levi A.; Chu, Richard C.; David, Milnes P.; Ellsworth Jr., Michael J.; Iyengar, Madhusudan K.; Schmidt, Roger R.; Simons, Robert E.

    2015-12-15

    Energy efficient control of cooling system cooling of an electronic system is provided based, in part, on weighted cooling effectiveness of the components. The control includes automatically determining speed control settings for multiple adjustable cooling components of the cooling system. The automatically determining is based, at least in part, on weighted cooling effectiveness of the components of the cooling system, and the determining operates to limit power consumption of at least the cooling system, while ensuring that a target temperature associated with at least one of the cooling system or the electronic system is within a desired range by provisioning, based on the weighted cooling effectiveness, a desired target temperature change among the multiple adjustable cooling components of the cooling system. The provisioning includes provisioning applied power to the multiple adjustable cooling components via, at least in part, the determined control settings.

  7. Effectiveness-weighted control of cooling system components

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Levi A.; Chu, Richard C.; David, Milnes P.; Ellsworth Jr., Michael J.; Iyengar, Madhusudan K.; Schmidt, Roger R.; Simmons, Robert E.

    2015-12-22

    Energy efficient control of cooling system cooling of an electronic system is provided based, in part, on weighted cooling effectiveness of the components. The control includes automatically determining speed control settings for multiple adjustable cooling components of the cooling system. The automatically determining is based, at least in part, on weighted cooling effectiveness of the components of the cooling system, and the determining operates to limit power consumption of at least the cooling system, while ensuring that a target temperature associated with at least one of the cooling system or the electronic system is within a desired range by provisioning, based on the weighted cooling effectiveness, a desired target temperature change among the multiple adjustable cooling components of the cooling system. The provisioning includes provisioning applied power to the multiple adjustable cooling components via, at least in part, the determined control settings.

  8. Use of probabilistic weights to enhance linear regression myoelectric control

    Science.gov (United States)

    Smith, Lauren H.; Kuiken, Todd A.; Hargrove, Levi J.

    2015-12-01

    Objective. Clinically available prostheses for transradial amputees do not allow simultaneous myoelectric control of degrees of freedom (DOFs). Linear regression methods can provide simultaneous myoelectric control, but frequently also result in difficulty with isolating individual DOFs when desired. This study evaluated the potential of using probabilistic estimates of categories of gross prosthesis movement, which are commonly used in classification-based myoelectric control, to enhance linear regression myoelectric control. Approach. Gaussian models were fit to electromyogram (EMG) feature distributions for three movement classes at each DOF (no movement, or movement in either direction) and used to weight the output of linear regression models by the probability that the user intended the movement. Eight able-bodied and two transradial amputee subjects worked in a virtual Fitts’ law task to evaluate differences in controllability between linear regression and probability-weighted regression for an intramuscular EMG-based three-DOF wrist and hand system. Main results. Real-time and offline analyses in able-bodied subjects demonstrated that probability weighting improved performance during single-DOF tasks (p amputees. Though goodness-of-fit evaluations suggested that the EMG feature distributions showed some deviations from the Gaussian, equal-covariance assumptions used in this experiment, the assumptions were sufficiently met to provide improved performance compared to linear regression control. Significance. Use of probability weights can improve the ability to isolate individual during linear regression myoelectric control, while maintaining the ability to simultaneously control multiple DOFs.

  9. Use of probabilistic weights to enhance linear regression myoelectric control.

    Science.gov (United States)

    Smith, Lauren H; Kuiken, Todd A; Hargrove, Levi J

    2015-12-01

    Clinically available prostheses for transradial amputees do not allow simultaneous myoelectric control of degrees of freedom (DOFs). Linear regression methods can provide simultaneous myoelectric control, but frequently also result in difficulty with isolating individual DOFs when desired. This study evaluated the potential of using probabilistic estimates of categories of gross prosthesis movement, which are commonly used in classification-based myoelectric control, to enhance linear regression myoelectric control. Gaussian models were fit to electromyogram (EMG) feature distributions for three movement classes at each DOF (no movement, or movement in either direction) and used to weight the output of linear regression models by the probability that the user intended the movement. Eight able-bodied and two transradial amputee subjects worked in a virtual Fitts' law task to evaluate differences in controllability between linear regression and probability-weighted regression for an intramuscular EMG-based three-DOF wrist and hand system. Real-time and offline analyses in able-bodied subjects demonstrated that probability weighting improved performance during single-DOF tasks (p linear regression control. Use of probability weights can improve the ability to isolate individual during linear regression myoelectric control, while maintaining the ability to simultaneously control multiple DOFs.

  10. Effect of ice massage on lower extremity functional performance and weight discrimination ability in collegiate footballers.

    Science.gov (United States)

    Sharma, Geeta; Noohu, Majumi Mohamad

    2014-09-01

    Cryotherapy, in the form of ice massge is used to reduce inflammation after acute musculoskeletal injury or trauma. The potential negative effects of ice massage on proprioception are unknown, despite equivocal evidence supporting its effectiveness. The purpose of the study was to test the influence of cooling on weight discrimination ability and hence the performance in footballers. The study was of same subject experimental design (pretest-posttest design). Thirty male collegiate football players, whose mean age was 21.07 years, participated in the study. The participants were assessed for two functional performance tests, single leg hop test and crossed over hop test and weight discrimination ability before and after ice massage for 5 minutes on hamstrings muscle tendon. Pre cooling scores of Single Leg Hop Test of the dominant leg in the subjects was 166.65 (± 10.16) cm and post cooling scores of the dominant leg was 167.25 (± 11.77) cm. Pre cooling scores of Crossed Over Hop Test of the dominant leg in the subjects was 174.14 (± 8.60) cm and post cooling scores of the dominant leg was 174.45 (± 9.28) cm. Pre cooling scores of Weight Discrimination Differential Threshold of the dominant leg in the subjects was 1.625 ± 1.179 kg compared with post cooling scores of the dominant leg 1.85 (± 1.91) kg. Pre cooling scores of single leg hop and crossed over hop test of the dominant leg in the subjects compared with post cooling scores of the dominant leg showed no significant differences and it was also noted that the weight discrimination ability (weight discrimination differential threshold) didn't show any significant difference. All the values are reported as mean ± SD. This study provides additional evidence that proprioceptive acuity in the hamstring muscles (biceps femoris) remains largely unaffected after ice application to the hamstrings tendon (biceps femoris).

  11. Body composition analyses by air displacement plethysmography in adults ranging from normal weight to extremely obese

    Science.gov (United States)

    Hames, Kazanna C.; Anthony, Steven J.; Thornton, John C.; Gallagher, Dympna; Goodpaster, Bret H.

    2014-01-01

    Objective To compare body composition parameters estimated by air displacement plethysmography (ADP) to dual x-ray absorptiometry (DXA) in body mass index (BMI) classifications that include extremely obese (BMI≥40.0kg/m2), and to examine if differences between analyses were influenced by BMI. Design and Methods Fat free mass (FFM,kg), fat mass (FM,kg) and body fat (BF,%) were analyzed with both technologies. Results All outcome measures of ADP and DXA were highly correlated (r≥0.95,Pobese classification; ADP estimated lower FFM and greater FM and BF (Pobese. PMID:24170704

  12. Evaluation of extreme temperature events in northern Spain based on process control charts

    Science.gov (United States)

    Villeta, M.; Valencia, J. L.; Saá, A.; Tarquis, A. M.

    2017-02-01

    Extreme climate events have recently attracted the attention of a growing number of researchers because these events impose a large cost on agriculture and associated insurance planning. This study focuses on extreme temperature events and proposes a new method for their evaluation based on statistical process control tools, which are unusual in climate studies. A series of minimum and maximum daily temperatures for 12 geographical areas of a Spanish region between 1931 and 2009 were evaluated by applying statistical process control charts to statistically test whether evidence existed for an increase or a decrease of extreme temperature events. Specification limits were determined for each geographical area and used to define four types of extreme anomalies: lower and upper extremes for the minimum and maximum anomalies. A new binomial Markov extended process that considers the autocorrelation between extreme temperature events was generated for each geographical area and extreme anomaly type to establish the attribute control charts for the annual fraction of extreme days and to monitor the occurrence of annual extreme days. This method was used to assess the significance of changes and trends of extreme temperature events in the analysed region. The results demonstrate the effectiveness of an attribute control chart for evaluating extreme temperature events. For example, the evaluation of extreme maximum temperature events using the proposed statistical process control charts was consistent with the evidence of an increase in maximum temperatures during the last decades of the last century.

  13. Impact of Early Nutrition on Body Composition in Children Aged 9.5 Years Born with Extremely Low Birth Weight

    Directory of Open Access Journals (Sweden)

    Sonja Stutte

    2017-02-01

    Full Text Available To evaluate body composition, metabolism and growth as well as their interaction with early nutrition in former extremely low birth weight infants (ELBW, we assessed qualitative and quantitative nutritional intake during initial hospitalization and infantile growth parameters in 61 former ELBW infants with a birth weight <1000 g. In two follow-up exams, physical and biochemical development were measured at 5.7 and at 9.5 years. At the second follow-up, in addition to biochemical reassessment, body composition was analyzed by dual-energy x-ray absorptiometry (DEXA. Protein intake between birth and discharge was associated with weight gain in the first six months of life (r = 0.51; p < 0.01. Weight catch-up preceded height catch-up. Protein intake in early infancy correlated highly significantly with abdominal fat mass (r = 0.49; p < 0.05, but not with lean body mass at 9.5 years (r = 0.30; not significant (n.s.. In contrast to nutrient intake, birth weight was associated with lean body mass (r = 0.433; p < 0.001. Early protein and carbohydrate intake were associated with high-density lipoprotein (HDL-cholesterol, and early catch-up growth correlated with fasting insulin at follow-up. Stepwise linear regression demonstrated that protein intake predicted fat mass (p < 0.05, whereas only gender and birth weight standard deviation score (SDS contributed significantly to lean body mass variation (p < 0.05. Our results suggest an important impact of early nutrient intake on body composition and metabolism in later childhood in ELBW children.

  14. Impact of Early Nutrition on Body Composition in Children Aged 9.5 Years Born with Extremely Low Birth Weight

    Science.gov (United States)

    Stutte, Sonja; Gohlke, Bettina; Peiler, Annika; Schreiner, Felix; Born, Mark; Bartmann, Peter; Woelfle, Joachim

    2017-01-01

    To evaluate body composition, metabolism and growth as well as their interaction with early nutrition in former extremely low birth weight infants (ELBW), we assessed qualitative and quantitative nutritional intake during initial hospitalization and infantile growth parameters in 61 former ELBW infants with a birth weight <1000 g. In two follow-up exams, physical and biochemical development were measured at 5.7 and at 9.5 years. At the second follow-up, in addition to biochemical reassessment, body composition was analyzed by dual-energy x-ray absorptiometry (DEXA). Protein intake between birth and discharge was associated with weight gain in the first six months of life (r = 0.51; p < 0.01). Weight catch-up preceded height catch-up. Protein intake in early infancy correlated highly significantly with abdominal fat mass (r = 0.49; p < 0.05), but not with lean body mass at 9.5 years (r = 0.30; not significant (n.s.). In contrast to nutrient intake, birth weight was associated with lean body mass (r = 0.433; p < 0.001). Early protein and carbohydrate intake were associated with high-density lipoprotein (HDL)-cholesterol, and early catch-up growth correlated with fasting insulin at follow-up. Stepwise linear regression demonstrated that protein intake predicted fat mass (p < 0.05), whereas only gender and birth weight standard deviation score (SDS) contributed significantly to lean body mass variation (p < 0.05). Our results suggest an important impact of early nutrient intake on body composition and metabolism in later childhood in ELBW children. PMID:28208596

  15. An intelligent active force control algorithm to control an upper extremity exoskeleton for motor recovery

    Science.gov (United States)

    Hasbullah Mohd Isa, Wan; Taha, Zahari; Mohd Khairuddin, Ismail; Majeed, Anwar P. P. Abdul; Fikri Muhammad, Khairul; Abdo Hashem, Mohammed; Mahmud, Jamaluddin; Mohamed, Zulkifli

    2016-02-01

    This paper presents the modelling and control of a two degree of freedom upper extremity exoskeleton by means of an intelligent active force control (AFC) mechanism. The Newton-Euler formulation was used in deriving the dynamic modelling of both the anthropometry based human upper extremity as well as the exoskeleton that consists of the upper arm and the forearm. A proportional-derivative (PD) architecture is employed in this study to investigate its efficacy performing joint-space control objectives. An intelligent AFC algorithm is also incorporated into the PD to investigate the effectiveness of this hybrid system in compensating disturbances. The Mamdani Fuzzy based rule is employed to approximate the estimated inertial properties of the system to ensure the AFC loop responds efficiently. It is found that the IAFC-PD performed well against the disturbances introduced into the system as compared to the conventional PD control architecture in performing the desired trajectory tracking.

  16. Positive and negative dimensions of weight control motivation.

    Science.gov (United States)

    Stotland, S; Larocque, M; Sadikaj, G

    2012-01-01

    This study examined weight control motivation among patients (N=5460 females and 547 males) who sought weight loss treatment with family physicians. An eight-item measure assessed the frequency of thoughts and feelings related to weight control "outcome" (e.g. expected physical and psychological benefits) and "process" (e.g. resentment and doubt). Factor analysis supported the existence of two factors, labeled Positive and Negative motivation. Positive motivation was high (average frequency of thoughts about benefits was 'every day') and stable throughout treatment, while Negative motivation declined rapidly and then stabilized. The determinants of changes in the Positive and Negative dimensions during treatment were examined within 3 time frames: first month, months 2-6, and 6-12. Maintenance of high scores on Positive motivation was associated with higher BMI and more disturbed eating habits. Early reductions in Negative motivation were greater for those starting treatment with higher weight and more disturbed eating habits, but less depression and stress, while later reductions in Negative motivation were predicted by improvements in eating habits, weight, stress and perfectionism. Clinicians treating obesity should be sensitive to fluctuations in both motivational dimensions, as they are likely to play a central role in determining long-term behavior and weight change.

  17. Damage control for devastating pelvic and extremity injuries.

    Science.gov (United States)

    Henry, S M; Tornetta, P; Scalea, T M

    1997-08-01

    This article focuses on some general principles of care and then discusses devastating pelvic injury secondary to both blunt and penetrating trauma. The authors describe the current approach to the mangled extremity and discuss indications for primary amputation.

  18. 'Resuscitation' of extremely preterm and/or low-birth-weight infants - time to 'call it'?

    Science.gov (United States)

    O'Donnell, Colm P F

    2008-01-01

    Since ancient times, various methods have been used to revive apparently stillborn infants; many were of dubious efficacy and had the potential to cause harm. Based largely on studies of acutely asphyxiated term animal models, clinical assessment and positive pressure ventilation have become the cornerstones of neonatal resuscitation over the last 40 years. Over the last 25 years, care of extremely preterm infants in the delivery room has evolved from a policy of indifference to one of increasingly aggressive support. The survival of these infants has improved considerably in recent years; this has not, however, necessarily been due to more aggressive resuscitation. Urban myths have evolved that all extremely preterm infants died before they were intubated, and that all such infants need to immediately intubated or they will quickly die. This has never been true. Clinical assessment of infants at birth is subjective. Also, many techniques used to support preterm infants at birth have not been well studied and there is evidence that they may be harmful. It may thus be argued that many of our well-intentioned resuscitation interventions are of dubious efficacy and have the potential to cause harm. 'Resuscitation' is an emotive term which means 'restoration of life'. Death, thankfully, is a rare presentation in the delivery room. Therefore, concerning neonatal 'resuscitation', it is time to 'call it' something else. This will allow us to dispassionately distinguish preterm infants who are dead, or nearly dead, from those who are merely at high risk of parenchymal lung disease. We may then be able to refine our interventions and determine what methods of support benefit these infants most.

  19. Oropharyngeal administration of mother's milk to prevent necrotizing enterocolitis in extremely low-birth-weight infants: theoretical perspectives.

    Science.gov (United States)

    Rodriguez, Nancy A; Caplan, Michael S

    2015-01-01

    The oropharyngeal administration of mother's milk-placing drops of milk onto the infant's oral mucosa-may serve as a preventative strategy against necrotizing enterocolitis (NEC) for extremely low-birth-weight (ELBW: birth weight milk to ELBW infants may serve to expose the infant's oropharynx to protective (immune and trophic) biofactors (also present in amniotic fluid) and may protect the infant against NEC. Emerging evidence suggests that this intervention may have many benefits for extremely premature infants including protection against bacteremia, NEC, and ventilator-associated pneumonia, an earlier attainment of full enteral feeds, enhanced maturation of oral feeding skills, improved growth, and enhanced breast-feeding outcomes. While more research is needed to definitively establish safety and efficacy of this intervention, this article will examine biological plausibility and will describe the theoretical mechanisms of protection against NEC for ELBW infants who receive this intervention. Nurses play a key role in advancing the science and practice of this intervention. Future directions for research and implications for nursing practice will also be presented.

  20. Body image and weight control in South Africans 15 years or older: SANHANES-1.

    Science.gov (United States)

    Mchiza, Zandile J; Parker, Whadi-Ah; Makoae, Mokhantso; Sewpaul, Ronel; Kupamupindi, Takura; Labadarios, Demetre

    2015-09-30

    South African studies have suggested that differences in obesity prevalence between groups may be partly related to differences in body image and body size dissatisfaction. However, there has never been a national study that measured body image and its relationship to weight control in the country. Hence, the main aim of the study was to examine body image in relation to body mass index and weight control in South Africa. A cross-sectional survey and a secondary analyses of data were undertaken for 6 411 South Africans (15+ years) participating in the first South African National Health and Nutrition Examination Survey. Body image was investigated in relation to weight status and attempts to lose or gain weight. Data were analysed using STATA version 11.0. Descriptive statistics are presented as counts (numbers), percentages, means, standard error of means, and 95 % confidence intervals. Any differences in values were considered to be significantly different if the confidence intervals did not overlap. Overall, 84.5 % participants had a largely distorted body image and 45.3 % were highly dissatisfied about their body size. Overweight and obese participants under estimated their body size and desired to be thinner. On the other hand, normal- and under-weight participants over estimated their body size and desired to be fatter. Only 12.1 and 10.1 % of participants attempted to lose or gain weight, respectively, mainly by adjusting dietary intake and physical activity. Body mass index appears to influence body image and weight adjustment in South Africa. South Africans at the extreme ends of the body mass index range have a largely distorted body image and are highly dissatisfied by it. This suggests a need for health education and beneficial weight control strategies to halt the obesity epidemic in the country.

  1. Macroscopic birefringence in liquid crystals from novel cyanobacterial polysaccharide with an extremely high molecular weight

    Science.gov (United States)

    Okajima-Kaneko, Maiko; Hayasaka-Kaneko, Daisaku; Miyazato, Shinji; Kaneko, Tatsuo

    2007-05-01

    We report an efficient method for extraction of anionic polysaccharides (PS) from cyanobacteria, Aphanothece sacrum; we used a hot alkaline solution (0.01 N NaOH) as an elution solvent in the first step of the extraction and isopropanol as a precipitation solvent in the last step. Thin fibers of PS were obtained at a high yield (50-80 % to the weight of the raw cyanobacterial sample). The spectroscopy and elemental analyses indicated the PS contains fucose, uronic acids (14.2 % by a carbazole-sulfuric acid method), a sugar unit containing amides. The solution of PS with a concentration of 1 wt% showed a very high viscosity (80 000cps) implying a high molecular weight, and a strong macroscopic birefringence with a texture typical of nematic liquid crystals was confirmed by crossed-polarizing microscopy (more than 0.5 wt%). The PS from A. sacrum may form a special structure rigid-rod enough to show LC phase and macroscopic birefringence.

  2. Interaction Between Orexin-A and Sleep Quality in Females in Extreme Weight Conditions.

    Science.gov (United States)

    Sauchelli, Sarah; Jiménez-Murcia, Susana; Fernández-García, Jose C; Garrido-Sánchez, Lourdes; Tinahones, Francisco J; Casanueva, Felipe F; Baños, Rosa M; Botella, Cristina; Crujeiras, Ana B; de la Torre, Rafael; Fernández-Real, Jose M; Frühbeck, Gema; Granero, Roser; Ortega, Francisco J; Rodríguez, Amaia; Zipfel, Stephan; Giel, Katrin E; Menchón, Jose M; Fernández-Aranda, Fernando

    2016-11-01

    The current study examined the relationship between plasma orexin-A and sleep in obesity. Concentrations of orexin-A and sleep were evaluated in 26 obese, 40 morbid obese and 32 healthy-weight participants. The sleep monitor Actiwatch AW7 and the Pittsburgh Sleep Quality Index were used to evaluate sleep. The Symptom Checklist-90-Revised was administered to assess symptoms of psychopathology. A higher weight status was associated with elevated orexin-A levels (p = .050), greater depression, anxiety and somatization symptoms (all: p < .001), and impoverished self-reported sleep quality (p < .001). A quadratic trend was found in objective sleep time, being longest in the obese group (p = .031). Structural equation modelling showed plasma orexin-A to be related to poor total sleep quality, which in turn was associated with elevated body mass index. Our data confirm an interaction between elevated plasma orexin-A concentrations and poor sleep that contributes to fluctuations in body mass index. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association. Copyright © 2016 John Wiley & Sons, Ltd and Eating Disorders Association.

  3. Controllability of Weighted and Directed Networks with Nonidentical Node Dynamics

    Directory of Open Access Journals (Sweden)

    Linying Xiang

    2013-01-01

    Full Text Available The concept of controllability from control theory is applied to weighted and directed networks with heterogenous linear or linearized node dynamics subject to exogenous inputs, where the nodes are grouped into leaders and followers. Under this framework, the controllability of the controlled network can be decomposed into two independent problems: the controllability of the isolated leader subsystem and the controllability of the extended follower subsystem. Some necessary and/or sufficient conditions for the controllability of the leader-follower network are derived based on matrix theory and graph theory. In particular, it is shown that a single-leader network is controllable if it is a directed path or cycle, but it is uncontrollable for a complete digraph or a star digraph in general. Furthermore, some approaches to improving the controllability of a heterogenous network are presented. Some simulation examples are given for illustration and verification.

  4. Access Request Trustworthiness in Weighted Access Control Framework

    Institute of Scientific and Technical Information of China (English)

    WANG Lun-wei; LIAO Xiang-ke; WANG Huai-min

    2005-01-01

    Weighted factor is given to access control policies to express the importance of policy and its effect on access control decision. According to this weighted access control framework, a trustworthiness model for access request is also given. In this model, we give the measure of trustworthiness factor to access request, by using some idea of uncertainty reasoning of expert system, present and prove the parallel propagation formula of request trustworthiness factor among multiple policies, and get the final trustworthiness factor to decide whether authorizing. In this model, authorization decision is given according to the calculation of request trustworthiness factor, which is more understandable, more suitable for real requirement and more powerful for security enhancement than traditional methods. Meanwhile the finer access control granularity is another advantage.

  5. Bivariate copulas on the exponentially weighted moving average control chart

    Directory of Open Access Journals (Sweden)

    Sasigarn Kuvattana

    2016-10-01

    Full Text Available This paper proposes four types of copulas on the Exponentially Weighted Moving Average (EWMA control chart when observations are from an exponential distribution using a Monte Carlo simulation approach. The performance of the control chart is based on the Average Run Length (ARL which is compared for each copula. Copula functions for specifying dependence between random variables are used and measured by Kendall’s tau. The results show that the Normal copula can be used for almost all shifts.

  6. [Implementing ambulatory prevention of thrombosis with low molecular weight heparin in plaster immobilization of the lower extremity].

    Science.gov (United States)

    Kock, H J; Schmit-Neuerburg, K P; Hanke, J; Terwort, A; Rudofsky, G; Hirche, H

    1994-12-01

    Plaster cast immobilisation following trauma is a major risk factor for the development of deep vein thrombosis. In our controlled, randomized and prospective study in patients with minor injuries the incidence of deep vein thrombosis was 4.3% in conservatively treated outpatients with plaster cast immobilisation of the leg (n = 163 control group without prophylaxis). By application of low molecular weight heparin once daily the number of deep vein thrombosis in the prophylaxis group (n = 176) was reduced to 0% (p = 0.006). No severe side effects of low molecular weight heparin were observed. Subcutaneous injections were self-applicated by 89% of males and 72% of females. We conclude that thromboprophylaxis with low molecular weight heparin once daily is effective to reduce the risk of deep vein thrombosis in outpatients with plaster cast immobilisation of the leg.

  7. Mitigating the Long term Operating Extreme Load through Active Control

    DEFF Research Database (Denmark)

    Koukoura, Christina; Natarajan, Anand

    2014-01-01

    The parameters influencing the long term extreme operating design loads are identified through the implementation of a Design of Experiment (DOE) method. A function between the identified critical factors and the ultimate out-of-plane loads on the blade is determined. Variations in the initial bl...... for different values of the integral gain as resulting in rotor speed error and the rate of change of rotor speed. Based on the results a new load case for the simulation of extreme loads during normal operation is also presented....

  8. Trends in survival among extremely-low-birth-weight infants (less than 1000 g without significant bronchopulmonary dysplasia

    Directory of Open Access Journals (Sweden)

    Botet Francesc

    2012-06-01

    Full Text Available Abstract Objective The aim of this study was to analyze the evolution from 1997 to 2009 of survival without significant (moderate and severe bronchopulmonary dysplasia (SWsBPD in extremely-low-birth-weight (ELBW infants and to determine the influence of changes in resuscitation, nutrition and mechanical ventilation on the survival rate. Study design In this study, 415 premature infants with birth weights below 1000 g (ELBW were divided into three chronological subgroups: 1997 to 2000 (n = 65, 2001 to 2005 (n = 178 and 2006 to 2009 (n = 172. Between 1997 and 2000, respiratory resuscitation in the delivery room was performed via a bag and mask (Ambu®, Ballerup, Sweden with 40-50% oxygen. If this procedure was not effective, oral endotracheal intubation was always performed. Pulse oximetry was never used. Starting on January 1, 2001, a change in the delivery room respiratory policy was established for ELBW infants. Oxygenation and heart rate were monitored using a pulse oximeter (Nellcor® attached to the newborn’s right hand. If resuscitation was required, ventilation was performed using a face mask, and intermittent positive pressure was controlled via a ventilator (Babylog2, Drägger. In 2001, a policy of aggressive nutrition was also initiated with the early provision of parenteral amino acids. We used standardized parenteral nutrition to feed ELBW infants during the first 12–24 hours of life. Lipids were given on the first day. The glucose concentration administered was increased by 1 mg/kg/minute each day until levels reached 8 mg/kg/minute. Enteral nutrition was started with trophic feeding of milk. In 2006, volume guarantee treatment was instituted and administered together with synchronized intermittent mandatory ventilation (SIMV + VG. The complications of prematurity were treated similarly throughout the study period. Patent ductus arteriosus was only treated when hemodynamically significant. Surgical closure of the

  9. Quality control methods in accelerometer data processing: identifying extreme counts.

    Directory of Open Access Journals (Sweden)

    Carly Rich

    Full Text Available BACKGROUND: Accelerometers are designed to measure plausible human activity, however extremely high count values (EHCV have been recorded in large-scale studies. Using population data, we develop methodological principles for establishing an EHCV threshold, propose a threshold to define EHCV in the ActiGraph GT1M, determine occurrences of EHCV in a large-scale study, identify device-specific error values, and investigate the influence of varying EHCV thresholds on daily vigorous PA (VPA. METHODS: We estimated quantiles to analyse the distribution of all accelerometer positive count values obtained from 9005 seven-year old children participating in the UK Millennium Cohort Study. A threshold to identify EHCV was derived by differentiating the quantile function. Data were screened for device-specific error count values and EHCV, and a sensitivity analysis conducted to compare daily VPA estimates using three approaches to accounting for EHCV. RESULTS: Using our proposed threshold of ≥ 11,715 counts/minute to identify EHCV, we found that only 0.7% of all non-zero counts measured in MCS children were EHCV; in 99.7% of these children, EHCV comprised < 1% of total non-zero counts. Only 11 MCS children (0.12% of sample returned accelerometers that contained negative counts; out of 237 such values, 211 counts were equal to -32,768 in one child. The medians of daily minutes spent in VPA obtained without excluding EHCV, and when using a higher threshold (≥19,442 counts/minute were, respectively, 6.2% and 4.6% higher than when using our threshold (6.5 minutes; p<0.0001. CONCLUSIONS: Quality control processes should be undertaken during accelerometer fieldwork and prior to analysing data to identify monitors recording error values and EHCV. The proposed threshold will improve the validity of VPA estimates in children's studies using the ActiGraph GT1M by ensuring only plausible data are analysed. These methods can be applied to define appropriate EHCV

  10. Neurotrophic Factor Control of Satiety and Body Weight

    Science.gov (United States)

    Xu, Baoji; Xie, Xiangyang

    2016-01-01

    Energy balance, the relationship between energy intake and expenditure, is regulated by a complex interplay of hormones, brain circuits and peripheral tissues. Leptin is an adipocyte-derived cytokine that suppresses appetite and increases energy expenditure. Ironically, obese individuals have high levels of plasma leptin and are resistant to leptin treatment. Neurotrophic factors, particularly ciliary neurotrophic factor (CNTF) and brain-derived neurotrophic factor (BDNF), are also important for the control of body weight. CNTF can overcome leptin resistance to reduce body weight, although CNTF and leptin activate similar signalling cascades. Mutations in the gene for BDNF lead to insatiable appetite and severe obesity. PMID:27052383

  11. Weight-related concerns and weight-control behaviors among overweight adolescents in Delhi, India: A cross-sectional study

    Directory of Open Access Journals (Sweden)

    Shrivastav Radhika

    2011-02-01

    Full Text Available Abstract Background Obesity is emerging as a public health problem among adolescents in India. The aim of this study was to describe specific weight-related concerns among school-going youth in Delhi, India and to assess the prevalence of weight control behaviors, including healthy and unhealthy ones. Differences by weight status, gender, grade level, and school-type (a proxy for SES in this setting are considered. Methods This study is cross-sectional by design. A sample of eighth and tenth graders (n = 1818 enrolled in Private (middle-high SES and Government (low SES schools (n = 8 in Delhi, India participated. All students' height and weight were measured. Students participated in a survey of weight-related concerns and weight-control behaviors, as well. Mixed-effects regression models were used to test for differences in weight-related concerns and weight-control behaviors across key factors of interest (i.e., weight status, gender, grade level, and SES. Results The combined prevalence of obesity and overweight was 16.6%, overall. Controlling one's weight was important to overweight and non-overweight youth, alike (94.2% v. 84.8%, p p Conclusions Interventions to promote healthy weight control should be pertinent to and well-received by school-going youth in India. Healthy weight control practices need to be explicitly encouraged and unhealthy practices reduced. Future interventions should address issues specific to body image, too, as body dissatisfaction was not uncommon among youth.

  12. [Ambulatory prevention of thrombosis with low molecular weight heparin in plaster immobilization of the lower extremity].

    Science.gov (United States)

    Kock, H J; Schmit-Neuerburg, K P; Hanke, J; Hakmann, A; Althoff, M; Rudofsky, G; Hirche, H

    1993-06-01

    Plaster cast immobilisation following trauma is a major risk factor for the development of deep vein thrombosis. In our controlled, randomized and prospective study on patients with minor injuries incidence of DVT in conservatively treated out-patients with plaster cast immobilisation of the leg was 3.9% in the control group (n = 126) without prophylaxis. By s.c. self-application of LMV heparin once daily the number of DVT in the prophylaxis group (n = 115) was reduced to 0. No severe side effects of NMH were observed. We conclude that thromboprophylaxis with LMW heparin once daily up to now conspiciously reduced the risk of DVT in outpatients with plaster cast immobilisation of the leg.

  13. Is there any role for terlipressin in the extremely low birth weight infant with refractory septic shock?

    Directory of Open Access Journals (Sweden)

    Francesca Bissolo

    2012-10-01

    Full Text Available Terlipressin, a synthetic long-acting analogue of vasopressin, has been investigated as a second line vasopressor in adults and children with refractory septic shock, i.e. not responding to fluid resuscitation and high-dose catecholamine administration. Little experience is available about the safety and efficacy of terlipressin in term and preterm newborns. We report the case of an extremely low birth weight infant with severe septic shock, unresponsive to fluids, noradrenalin and hydrocortisone, in whom terlipressin was attempted as a rescue drug. Despite three doses of terlipressin, administered 6-hourly, the patient remained profoundly hypotensive and eventually died. Further studies are required before any recommendation on the use of terlipressin in term or preterm newborns with septic shock can be made.

  14. Hybrid Short Term Wind Speed Forecasting Using Variational Mode Decomposition and a Weighted Regularized Extreme Learning Machine

    Directory of Open Access Journals (Sweden)

    Nantian Huang

    2016-11-01

    Full Text Available Accurate wind speed forecasting is a fundamental element of wind power prediction. Thus, a new hybrid wind speed forecasting model, using variational mode decomposition (VMD, the partial autocorrelation function (PACF, and weighted regularized extreme learning machine (WRELM, is proposed to improve the accuracy of wind speed forecasting. First, the historic wind speed time series is decomposed into several intrinsic mode functions (IMFs. Second, the partial correlation of each IMF sequence is analyzed using PACF to select the optimal subfeature set for particular predictors of each IMF. Then, the predictors of each IMF are constructed in order to enhance its strength using WRELM. Finally, wind speed is obtained by adding up all the predictors. The experiment, using real wind speed data, verified the effectiveness and advancement of the new approach.

  15. Longitudinal automatic control system for a light weight aircraft

    Directory of Open Access Journals (Sweden)

    Cristian VIDAN

    2016-12-01

    Full Text Available This paper presents the design of an automatic control system for longitudinal axis of a light weight aircraft. To achieve this goal it is important to start from the mathematical model in longitudinal plane and then to determine the steady-state parameters for a given velocity and altitude. Using MATLAB Software the mathematical model in longitudinal plane was linearized and the system transfer functions were obtained. To determine the automatic control design we analyzed the stability of the linearized model for each input. After the stability problem was solved, using MATLAB-Simulink Software we designed the control system architecture and we considered that the objective for a stable flight was to continuously adjust the pitch angle θ through control of elevator and velocity through control of the throttle. Finally, we analyzed the performance of the designed longitudinal control system and the results highlighted in graphs outline that the purpose for which it was designed was fulfilled.

  16. Extreme challenges on cardiovascular control during gravity transitions

    Science.gov (United States)

    Verheyden, B.; Beckers, F.; Aubert, A. E.

    Introduction. During parabolic flights transient periods of hypergravity and microgravity are created. These periods cause translocations of bodily fluids in the longitudinal axis of the body, leading to altered cardiac preload and afterload. These extreme orthostatic challenges provide a unique platform to study baroreflex-mediated responses of the cardiovascular autonomic control system. This might have important features for the development of a model of cardiovascular deconditioning that is observed in a variety of patient populations. Purpose. Until now, due to methodological restrictions, most studies have been concentrating on the analysis of cardiovascular variability in time domain. The purpose of this study is to evaluate heart rate variability (HRV) and blood pressure variability (BPV) simultaneously, using frequency domain analysis techniques (low frequency power (LF: 0.04-0.15 Hz); high frequency power (HF: 0.16-0.4 Hz)), providing additional information about cardiac and vasomotor sympathetic modulation during gravity transitions. Methods. 12 healthy non-medicated volunteers (age = 24 ± 2.5 yr) underwent continuous ECG and blood pressure (BP) recordings during the 32nd and 34th parabolic flight campaign organized by ESA. The subjects performed 15 parabolas in supine and 15 parabolas in standing position. 5 transient gravity phases were abstracted; phase 1 and 5: before and after the parabola (1G); phase 2 and 4: at the ascending and descending leg of the parabola (2G); phase 3: at the apex of the parabola (0g). Phase 2, 3 and 4 last 20 seconds. Results. No significant differences were found in HRV and BPV parameters in supine position between the different gravity phases. In standing position, mean RR- interval was higher during 0G (900 ± 103 ms) compared to 1G (700 ± 87 ms) and 2G (600 ± 94 ms). Mean arterial BP remained relatively constant during 0G but tended to decrease during 2G (102 ± 2 mmHg vs. 105 ± 3 mmHg). Positive correlations were

  17. Frequency weighted model predictive control of wind turbine

    DEFF Research Database (Denmark)

    Klauco, Martin; Poulsen, Niels Kjølstad; Mirzaei, Mahmood;

    2013-01-01

    This work is focused on applying frequency weighted model predictive control (FMPC) on three blade horizontal axis wind turbine (HAWT). A wind turbine is a very complex, non-linear system influenced by a stochastic wind speed variation. The reduced dynamics considered in this work...... are the rotational degree of freedom of the rotor and the tower for-aft movement. The MPC design is based on a receding horizon policy and a linearised model of the wind turbine. Due to the change of dynamics according to wind speed, several linearisation points must be considered and the control design adjusted...... accordingly. In practice is very hard to measure the effective wind speed, this quantity will be estimated using measurements from the turbine itself. For this purpose stationary predictive Kalman filter has been used. Stochastic simulations of the wind turbine behaviour with applied frequency weighted model...

  18. Relationships among Subjective Social Status, Weight Perception, Weight Control Behaviors, and Weight Status in Adolescents: Findings from the 2009 Korea Youth Risk Behaviors Web-Based Survey

    Science.gov (United States)

    Ha, Yeongmi; Choi, Eunsook; Seo, Yeongmi; Kim, Tae-gu

    2013-01-01

    Background: This study identified relationships among subjective social status (SSS), weight perception, weight control behaviors, and weight status in Korean adolescents using nationally representative data collected from the 2009 Korea Youth Risk Behaviors Web-Based Survey. Methods: Data from 67,185 students aged 12-18 years were analyzed.…

  19. Relationships among Subjective Social Status, Weight Perception, Weight Control Behaviors, and Weight Status in Adolescents: Findings from the 2009 Korea Youth Risk Behaviors Web-Based Survey

    Science.gov (United States)

    Ha, Yeongmi; Choi, Eunsook; Seo, Yeongmi; Kim, Tae-gu

    2013-01-01

    Background: This study identified relationships among subjective social status (SSS), weight perception, weight control behaviors, and weight status in Korean adolescents using nationally representative data collected from the 2009 Korea Youth Risk Behaviors Web-Based Survey. Methods: Data from 67,185 students aged 12-18 years were analyzed.…

  20. Alternative growth functions for predicting body, carcass, and breast weight in ducks: Lomolino equation and extreme value function.

    Science.gov (United States)

    Faridi, A; Murawska, D; Golian, A; Mottaghitalab, M; Gitoee, A; Lopez, S; France, J

    2014-04-01

    In this study, 2 alternative growth functions, the Lomolino and the extreme value function (EVF), are introduced and their ability to predict body, carcass, and breast weight in ducks evaluated. A comparative study was carried out of these equations with standard growth functions: Gompertz, exponential, Richards, and generalized Michaelis-Menten. Goodness of fit of the functions was evaluated using R(2), mean square error, Akaike information criterion, and Bayesian information criterion, whereas bias factor, accuracy factor, Durbin-Watson statistic, and number of runs of sign were the criteria used for analysis of residuals. Results showed that predictive performance of all functions was acceptable, though the Richards and exponential equations failed to converge in a few cases for both male and female ducks. Based on goodness-of-fit statistics, the Richards, Gompertz, and EVF were the best equations whereas the worst fits to the data were obtained with the exponential. Analysis of residuals indicated that, for the different traits investigated, the least biased and the most accurate equations were the Gompertz, EVF, Richards, and generalized Michaelis-Menten, whereas the exponential was the most biased and least accurate. Based on the Durbin-Watson statistic, all models generally behaved well and only the exponential showed evidence of autocorrelation for all 3 traits investigated. Results showed that with all functions, estimated final weights of males were higher than females for the body, carcass, and breast weight profiles. The alternative functions introduced here have desirable advantages including flexibility and a low number of parameters. However, because this is probably the first study to apply these functions to predict growth patterns in poultry or other animals, further analysis of these new models is suggested.

  1. Catch–up growth in the first two years of life in Extremely Low Birth Weight (ELBW) infants is associated with lower body fat in young adolescence

    Science.gov (United States)

    Jacobs, Lotte; Rayyan, Maissa; van Tienoven, Theun Pieter; Ortibus, Els; Levtchenko, Elena

    2017-01-01

    Aim To investigate growth patterns and anthropometrics in former extremely low birth weight (ELBW, 0.67 SDS. At 11 years, anthropometrics, neurocognitive performance, body composition, grip strength and puberty scores were assessed. Results ELBW neonates displayed extra–uterine growth restriction with mean Z–scores for height, weight and head circumference of –0.77, –0.93 and –0.46 at birth, –1.61, –1.67 and –0.72 at 9 months, –1.22, –1.61 and –0.84 at 24 months, and –0.42, –0.49 and –1.09 at 11 years. ELBW children performed consistently worse on neurocognitive testing with an average intelligence quotient equivalent at 11 years of 92.5 (SD 13.1). Catch–up growth was not associated with neurocognitive performance. Compared to controls, ELBW cases had lower grip strength (13.6 vs. 15.9 kg) and percentage lean body weight (75.1 vs. 80.5%), but higher body fat (24.6 vs. 19.2%) and advanced puberty scores at 11 years (all P≤0.025). Catch–up growth for weight and height in the first two years of life in cases was associated with a lower percentage body fat compared to cases without catch–up growth (16.8% catch-up growth for weight vs. 25.7%, P<0.001; 20.9% catch-up for height vs. 25.8%, P = 0.049). Conclusions In young adolescence, former ELBW children still have difficulties to reach their target height. Compared to normal birth weight controls, ELBW adolescents show lower neurocognitive performance and grip strength and a higher percentage body fat, a potential risk factor for adverse health outcomes in adulthood. Our key finding is that catch–up growth in ELBW children in the first two years of life is associated with a lower percentage body fat and is therefore likely to be beneficial. PMID:28278233

  2. Modeling and simulating command and control for organizations under extreme situations

    CERN Document Server

    Moon, Il-Chul; Kim, Tag Gon

    2013-01-01

    Commanding and controlling organizations in extreme situations is a challenging task in military, intelligence, and disaster management. Such command and control must be quick, effective, and considerate when dealing with the changing, complex, and risky conditions of the situation. To enable optimal command and control under extremes, robust structures and efficient operations are required of organizations. This work discusses how to design and conduct virtual experiments on resilient organizational structures and operational practices using modeling and simulation. The work illustrates key a

  3. Test of visuospatial construction: Validity evidence in extremely low birth weight and late preterm children at early school age.

    Science.gov (United States)

    Rider, G Nicole; Weiss, Brandi A; McDermott, Adam T; Hopp, Crista A; Baron, Ida Sue

    2016-01-01

    The Test of Visuospatial Construction (TVSC), a measure of visuoconstruction that does not rely on upper extremity motor response or written production, was administered to extremely low birth weight (ELBW), late preterm (LPT), and term participants at preschool (n = 355) and kindergarten (n = 265) ages. TVSC showed statistically significant weak-to-moderate positive correlations (age 3: r = .118-.303; age 6: r = .138-.348) with Developmental VMI, Differential Ability Scales-II Copying, Matrices, and Pattern Construction subtests, Baron-Hopkins Board Test, and the Purdue Pegboard. One-way ANOVA indicated ELBW performed worse than Term (p = .044) on visuospatial construction at age 3 with a small-to-medium effect size (d = -0.43). No other statistically significant differences were found at age 3 on the TVSC (ELBW/LPT: p = .608, d = -0.17; LPT/Term: p = .116, d = -0.31). At age 6, ELBW participants performed worse than LPT participants (p = .027) and Term participants (p = .012); LPT participants did not differ from Term participants. Small effect sizes at age 3 (ELBW < LPT, d = -0.17; ELBW < Term, d = -0.43) were notably larger at age 6 (ELBW < LPT, d = -0.42; ELBW < Term, d = -0.53). Important practical differences showing LPT participants performed below Term participants (d = -0.31) at age 3 were no longer evident at age 6 (d = -0.097). These findings provide preliminary evidence of TVSC validity supporting its use to detect neuropsychological impairment and to recommend appropriate interventions in young preterm children.

  4. Molecular biomarkers for weight control in obese individuals subjected to a multi-phase dietary intervention

    DEFF Research Database (Denmark)

    Bolton, Jennifer L; Montastier, Emilie; Carayol, Jérôme

    2017-01-01

    Context: While calorie restriction has proven beneficial for weight loss, long-term weight control is variable between individuals. Objective: To identify biomarkers of successful weight control during a dietary intervention (DI). Design, Setting, and Participants: Adipose tissue (AT) transcripto......-controllers. Interestingly, ASPN is a TGFβ1 inhibitor. Conclusions: We found circulating biomarkers associated with weight control, which could influence weight management strategies, and genes that may be prognostic for successful weight control.......Context: While calorie restriction has proven beneficial for weight loss, long-term weight control is variable between individuals. Objective: To identify biomarkers of successful weight control during a dietary intervention (DI). Design, Setting, and Participants: Adipose tissue (AT......) transcriptomes were compared between 21 obese individuals that either maintained weight loss or regained weight during the DI. Results were validated on 310 individuals from the same study using RT-qPCR, and protein levels of potential circulating biomarkers measured by ELISA. Intervention: Individuals underwent...

  5. Fluconazole prophylaxis in extremely low birth weight infants and neurodevelopmental outcomes and quality of life at 8 to 10 years of age.

    Science.gov (United States)

    Kaufman, David A; Cuff, Amy L; Wamstad, Julia B; Boyle, Robert; Gurka, Matthew J; Grossman, Leigh B; Patrick, Peter

    2011-05-01

    To examine the long-term effects of fluconazole prophylaxis in extremely low birth weight infants. Neurodevelopmental status and quality of life of survivors from a randomized, placebo-controlled trial of fluconazole prophylaxis were evaluated at 8 to 10 years of life using the Vineland Adaptive Behavior Scales-II (VABS-II) and the Child Health Questionnaire Parent-Completed Form 28 (CHQ-PF28), respectively. VABS-II Domain Scores for the fluconazole-treated (n = 21; 9.1 ± 0.7 years) compared with the placebo group (n = 17; 9.3 ± 0.8 years) were similar for communication [94.6 (±14.8) versus 92.6 (±12.6), P = .65], daily living skills [87.9 (±10.6) versus 87.4 (±9.3), P = .89], socialization [97.2 (±9.2) versus 94.4 (±7.9), P = .31], and motor skills [92.1 (±17.8) versus 95.1 (±14.6), P = .57]. Internalizing and externalizing behaviors and maladaptive behavior index were also similar. The CHQ-PF28 revealed no differences between the two groups regarding quality of life. Survivors were also happy or satisfied with school (90% versus 100%, P = .49), friendships (90% versus 88%, P = 1.00), and life (95% versus 100%, P = 1.00). Self esteem scores were 87.3 ± 15.7 versus 89.7 ± 10.4 (P = .59). There were also no differences between groups regarding emotional difficulties or behavior problems. Fluconazole prophylaxis for the prevention of invasive Candida infections is safe in extremely low birth weight infants and does not appear to be associated with any long-term adverse effects on neurodevelopment and quality of life at 8 to 10 years of life. Copyright © 2011 Mosby, Inc. All rights reserved.

  6. Health related quality of life after extremely preterm birth: a matched controlled cohort study

    Directory of Open Access Journals (Sweden)

    Eide Geir E

    2010-05-01

    Full Text Available Abstract Background The majority of infants born before the last trimester now grow up. However, knowledge on subsequent health related quality of life (HRQoL is scarce. We therefore aimed to compare HRQoL in children born extremely preterm with control children born at term. Furthermore, we assessed HRQoL in relation to perinatal and neonatal morbidity and to current clinical and sociodemographic characteristics. Method The Child Health Questionnaire (CHQ-PF50 and a general questionnaire were applied in a population based cohort of 10 year old children born at gestational age ≤ 28 weeks or with birth weight ≤ 1000 grams in Western Norway in 1991-92 and in term-born controls, individually matched for gender and time of birth. The McNemar test and paired t-tests were used to explore group differences between preterms and matched controls. Paired regression models and analyses of interaction (SPSS mixed linear model were used to explore potential effects of sociodemographic and clinical characteristics on HRQoL in the two groups. Results All 35 eligible preterm children participated. None had major impairments. Learning and/or attention problems were present in 71% of preterms and 20% of controls (odds ratio (OR: 7.0; 95% confidence interval (CI: 2.2 to 27.6. Insufficient professional support was described by 36% of preterm vs. 3% of control parents (OR: infinite; CI: 2.7 to infinite. Preterms scored lower on eight CHQ-PF50 sub-scales and the two summary scores, boys accounting for most of the deficits in areas of behavior, psychosocial functioning and parental burden. HRQoL was associated with learning and/or attention problems in both preterm and control children, significantly more so in preterms in areas related to health and parental burden. Within the preterm group, HRQoL was mostly unrelated to perinatal and neonatal morbidity. Conclusions HRQoL for children born extremely preterm, and particularly for boys, was described by parents to

  7. Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of China: A Multi-center Study

    Science.gov (United States)

    Lin, Hui-Jia; Du, Li-Zhong; Ma, Xiao-Lu; Shi, Li-Ping; Pan, Jia-Hua; Tong, Xiao-Mei; Li, Qiu-Ping; Zhou, Jian-Guo; Yi, Bing; Liu, Ling; Chen, Yun-Bing; Wei, Qiu-Fen; Wu, Hui-Qing; Li, Mei; Liu, Cui-Qing; Gao, Xi-Rong; Xia, Shi-Wen; Li, Wen-Bin; Yan, Chao-Ying; He, Ling; Liang, Kun; Zhou, Xiao-Yu; Han, Shu-Ping; Lyu, Qin; Qiu, Yin-Ping; Li, Wen; Chen, Dong-Mei; Lu, Hong-Ru; Liu, Xiao-Hong; Liu, Hong; Lin, Zhen-Lang; Liu, Li; Zhu, Jia-Jun; Xiong, Hong; Yue, Shao-Jie; Zhuang, Si-Qi

    2015-01-01

    Background: With the progress of perinatal medicine and neonatal technology, more and more extremely low birth weight (ELBW) survived all over the world. This study was designed to investigate the short-term outcomes of ELBW infants during their Neonatal Intensive Care Unit (NICU) stay in the mainland of China. Methods: All infants admitted to 26 NICUs with a birth weight (BW) < l000 g were included between January l, 2011 and December 31, 2011. All the data were collected retrospectively from clinical records by a prospectively designed questionnaire. The data collected from each NICU transmitted to the main institution where the results were aggregated and analyzed. Categorical variables were performed with Pearson Chi-square test. Binary Logistic regression analysis was used to detect risk factors. Results: A total of 258 ELBW infants were admitted to 26 NICUs, of whom the mean gestational age (GA) was 28.1 ± 2.2 weeks, and the mean BW was 868 ± 97 g. The overall survival rate at discharge was 50.0%. Despite aggressive treatment 60 infants (23.3%) died and another 69 infants (26.7%) died after medical care withdrawal. Furthermore, the survival rate was significantly higher in coastal areas than inland areas (53.6% vs. 35.3%, P = 0.019). BW < 750 g and GA < 28 weeks were the largest risk factors, and being small for gestational age was a protective factor related to mortality. Respiratory distress syndrome was the most common complication. The incidence of patent ductus arteriosus, intraventricular hemorrhage, periventricular leukomalacia, bronchopulmonary dysplasia, retinopathy of prematurity was 26.2%, 33.7%, 6.7%, 48.1%, and 41.4%, respectively. Ventilator associated pneumonia was the most common hospital acquired infection during hospitalization. Conclusions: Our study was the first survey that revealed the present status of ELBW infants in the mainland of China. The mortality and morbidity of ELBW infants remained high as compared to other developed

  8. Neurodevelopmental sequelae in premature newborns with extremely low weight and with very low weight at two years of age who left the Neonatal Intensive Care Unit of the Hospital Nacional Edgardo Rebagliati Martins 2009-2014

    Directory of Open Access Journals (Sweden)

    Carmen Fernández Sierra

    2017-02-01

    Full Text Available Objective: The purpose of this study is to describe the neurodevelopmental sequelae in premature newborns with extremely low weight and with very low weight at two years of age who left the Neonatal Intensive Care Unit of the Hospital Nacional Edgardo Rebagliati Martins. Materials and methods: A descriptive, retrospective, cross-sectional study in a population of 190 premature newborns with extremely low weight and with very low weight born from January 2009 to June 2014 who left the Neonatal Intensive Care Unit and took part in the follow-up program. The psychomotor development, sensorineural hearing loss, retinopathy of prematurity, presence of cerebral palsy and convulsive syndrome were assessed. Results: The average weight at birth was 1,180.53 ± 212.40 grams with a gestational age of 29.86 ± 2.33 weeks, and 51.58% of the newborns were male. Forty-two point six three percent (42.63% of the premature newborns with very low weight showed retardation of psychomotor development; 25.26%, retinopathy; 13.68%, sensorineural hearing loss; 3.68%, cerebral palsy; and 3.68%, convulsive syndrome. Fifty-two point two seven percent (52.27% of the premature newborns with extremely low weight showed retardation of psychomotor development; 50%, retinopathy; 15.91%, sensorineural hearing loss; and 2.27%, convulsive syndrome. Conclusions: Retardation of psychomotor development and retinopathy were the most important complications shown by premature newborns with extremely low weight and with very low weight at two years of age.

  9. High frequencies of elevated alkaline phosphatase activity and rickets exist in extremely low birth weight infants despite current nutritional support

    Directory of Open Access Journals (Sweden)

    Parker Bruce R

    2009-07-01

    Full Text Available Abstract Background Osteopenia and rickets are common among extremely low birth weight infants (ELBW, Methods We evaluated all ELBW infants admitted to Texas Children's Hospital NICU in 2006 and 2007. Of 211 admissions, we excluded 98 patients who were admitted at >30 days of age or did not survive/stay for >6 weeks. Bone radiographs obtained in 32 infants were reviewed by a radiologist masked to laboratory values. Results In this cohort of 113 infants, P-APA was found to have a significant inverse relationship with BW, gestational age and serum phosphorus. In paired comparisons, P-APA of infants Conclusion Elevation of P-APA >600 IU/L was very common in ELBW infants. BW was significantly inversely related to both P-APA and radiologic rickets. No single value of P-APA was related to radiological findings of rickets. Given the very high risk of osteopenia and rickets among ELBW infants, we recommend consideration of early screening and early mineral supplementation, especially among infants

  10. Executive functions in extremely low birth weight and late-preterm preschoolers: effects on working memory and response inhibition.

    Science.gov (United States)

    Baron, Ida Sue; Kerns, Kimberly A; Müller, Ulrich; Ahronovich, Margot D; Litman, Fern R

    2012-01-01

    Executive function (EF) refers to fundamental capacities that underlie more complex cognition and have ecological relevance across the individual's lifespan. However, emerging executive functions have rarely been studied in young preterm children (age 3) whose critical final stages of fetal development are interrupted by their early birth. We administered four novel touch-screen computerized measures of working memory and inhibition to 369 participants born between 2004 and 2006 (52 Extremely Low Birth Weight [ELBW]; 196 late preterm; 121 term-born). ELBW performed worse than term-born on simple and complex working memory and inhibition tasks and had the highest percentage of incomplete performance on a continuous performance test. The latter finding indicates developmental immaturity and the ELBW group's most at-risk preterm status. Additionally, late-preterm participants performed worse compared with term-born on measures of complex working memory but did not differ from those term-born on response inhibition measures. These results are consistent with a recent literature that identifies often subtle but detectable neurocognitive deficits in late-preterm children. Our results support the development and standardization of computerized touch-screen measures to assess EF subcomponent abilities during the formative preschool period. Such measures may be useful to monitor the developmental trajectory of critical executive function abilities in preterm children, and their use is necessary for timely recognition of deficit and application of appropriate interventional strategies.

  11. Weight change in control group participants in behavioural weight loss interventions: a systematic review and meta-regression study

    Directory of Open Access Journals (Sweden)

    Waters Lauren

    2012-08-01

    Full Text Available Abstract Background Unanticipated control group improvements have been observed in intervention trials targeting various health behaviours. This phenomenon has not been studied in the context of behavioural weight loss intervention trials. The purpose of this study is to conduct a systematic review and meta-regression of behavioural weight loss interventions to quantify control group weight change, and relate the size of this effect to specific trial and sample characteristics. Methods Database searches identified reports of intervention trials meeting the inclusion criteria. Data on control group weight change and possible explanatory factors were abstracted and analysed descriptively and quantitatively. Results 85 trials were reviewed and 72 were included in the meta-regression. While there was no change in control group weight, control groups receiving usual care lost 1 kg more than control groups that received no intervention, beyond measurement. Conclusions There are several possible explanations why control group changes occur in intervention trials targeting other behaviours, but not for weight loss. Control group participation may prevent weight gain, although more research is needed to confirm this hypothesis.

  12. Motor Controller for Extreme Environments Based on SiGe Project

    Data.gov (United States)

    National Aeronautics and Space Administration — The proposed innovation is a motor-control subsystem capable of operation in extreme environments, including those to be encountered on the Moon and Mars....

  13. Patellar Taping, Patellofemoral Pain Syndrome, Lower Extremity Kinematics, and Dynamic Postural Control

    OpenAIRE

    Aminaka, Naoko; Gribble, Phillip A

    2008-01-01

    Context: Patellar taping has been a part of intervention for treatment of patellofemoral pain syndrome (PFPS). However, research on the efficacy of patellar taping on lower extremity kinematics and dynamic postural control is limited.

  14. Risk Factors Of Low Birth Weight; Case-Control Study

    Directory of Open Access Journals (Sweden)

    Özgür Önal

    2017-06-01

    Full Text Available Low birth weight (LBW (defined as a birth weight of less than 2500 grams is associated with fetal and neonatal morbidity and mortality, impaired cognitive development, and the advent of chronic diseases in later life. The global incidence of LBW is around 15,5%. The aim of this study was to identify risk factors for low birthweight in the centre of Denizli province. A case-control study was carried out and mothers of 295 newborns with birthweight between 1500-2499 g (cases and 302 newborns with birthweight between 2500-4000 g (controls were analyzed. The questionnare was applied to women using face to face technics between July,2009 and June,2010 . The questionnare included birth weight and birth lenght of newborn, the date of last pregnacy and type of last delivery, profile of mother, anthropometric measures, life styles, habits, addictions, sociodemographic and socioeconomic characteristics of mother and father of newborn. Analysis included frequency and percent distributions, means, standart deviations. In group comparisions for categorical variable, chi square test and odds ratio (OR was used. Logistic regression model was performed for some selected risk factors. P<0.05 was considered statistically significant. Statistical Package for Social Sciences (SPSS program, Version 10 was used for data entry and analysis. When backward logistic regression model was performed for some selected factors in relation to low birth weight, there was a positive relationship between multiple pregnancy [OR(95%CI 18.50 (8.54, 40.39], BMI lower than 20 kg/m2 of mother before pregnancy andemployment status [OR(95%CI 1.98 (1.23, 3.19], weight gain of 7 kg and under during pregnanacy [OR(95%CI 2.49 (1.56, 3.96], a history of giving birth to low birth weight infant [OR(95%CI 3.44 (1.69, 7.02], first- degree and second- degree relative’s histories of giving birth to low birth weight infant [OR(95%CI 4.28 (2.61, 6.94], X- ray exposure in the three months before and

  15. Overweight Adolescents' Self-Perceived Weight and Weight Control Behaviour: HBSC Study in Finland 1994–2010

    OpenAIRE

    Kristiina Ojala; Jorma Tynjälä; Raili Välimaa; Jari Villberg; Lasse Kannas

    2012-01-01

    Introduction. Overweight and perception of being overweight, may lead adolescent to lose weight. The aim of the present study was to investigate overweight adolescents’ self-perceived weight, body dissatisfaction, and weight control behaviour during 1994–2010 in Finland. Methods. The country-representative, cross-sectional data of 15-year olds were obtained from the Health Behaviour in School-aged Children (HBSC) study, conducted in 1994 ( = 1 1 9 4 ; males: 48%), 1998 ( = 1 5 4 5 ; 49%),...

  16. A pilot study of myoelectrically controlled FES of upper extremity

    NARCIS (Netherlands)

    Thorsen, Rune; Spadone, Rafaella; Ferrarin, Maurizio

    2001-01-01

    Functional electrical stimulation (FES) of upper limbs can be used for the recovery of some hand functions on patients with CNS lesions. This study deals with the control of FES by means of myoelectrical activity detected from voluntarily activated paretic muscles. The specific aim of this paper is

  17. Small for gestational age and poor fluid intelligence in childhood predict externalizing behaviors among young adults born at extremely low birth weight.

    Science.gov (United States)

    Lahat, Ayelet; Van Lieshout, Ryan J; Saigal, Saroj; Boyle, Michael H; Schmidt, Louis A

    2015-02-01

    Although infants born at extremely low birth weight (ELBW; birth weight intelligence. As young adults, a subset of ELBW survivors free of major neurosensory impairments provided self-reports of personality characteristics related to psychopathology. Data from 66 participants indicated that, as predicted, the association between ELBW and externalizing behaviors was moderated by fluid intelligence. Specifically, ELBW individuals with poor fluid intelligence who were born small for gestational age (birth weight intelligence might be a cognitive mechanism contributing to the development of psychopathology among nonimpaired individuals who were born at ELBW and small for gestational age.

  18. [Quality of life according to self-perceived weight, weight control behaviors, and gender among adolescent university students in Mexico].

    Science.gov (United States)

    Hidalgo-Rasmussen, Carlos Alejandro; Hidalgo-San Martín, Alfredo; Rasmussen-Cruz, Bettylú; Montaño-Espinoza, Rosa

    2011-01-01

    The aim of this study was to analyze quality of life (QoL) according to self-perceived weight and weight control behaviors, by gender. The sample consisted of 2,401 adolescent students (17-19 years of age) enrolled from 2007 to 2009 at a Mexican university; 61.9% were women, 19.4% worked, and 99.2% were single. An online self-administered questionnaire was used that included the perceptual module of the YQOL-R and seven items on body weight, adapted from YRBS 2007. 52% of women and 31.7% of men were attempting to lose weight. The highest QoL scores were in students who felt they were near the right weight, those who were attempting to maintain the same weight, and those who exercised. Lowest QoL was reported by those who considered themselves overweight, were trying to lose weight, were eating less, were skipping meals, or were using unsupervised dieting, vomiting, or laxatives. In women, QoL differed between those maintaining the same weight, gaining weight, and losing weight, while QoL in men only differed for those attempting to gain weight. The findings could be useful in educational processes, preventive programs, and assessment of interventions.

  19. Associations of Trying to Lose Weight, Weight Control Behaviors, and Current Cigarette Use among US High School Students

    Science.gov (United States)

    Johnson, Jonetta L.; Eaton, Danice K.; Pederson, Linda L.; Lowry, Richard

    2009-01-01

    Background: Approximately one-quarter of high school students currently use cigarettes. Previous research has suggested some youth use smoking as a method for losing weight. The purpose of this study was to describe the association of current cigarette use with specific healthy and unhealthy weight control practices among 9th-12th grade students…

  20. Short-term hunger intensity changes following ingestion of a meal replacement bar for weight control.

    Science.gov (United States)

    Rothacker, Dana Q; Watemberg, Salo

    2004-05-01

    Meal replacement products for weight loss are popular and safe for most unsupervised consumers desiring to lose weight. Previously we reported that the thickness of meal replacement diet shakes had a direct and significant effect on hunger intensity during the first 2 h and that hunger intensity scores for liquid meal replacements were significantly below baseline for 3 h following consumption (Mattes & Rothacker, 2001) This study uses the same protocol to investigate meal replacement bars designed for overweight consumers. Subjects were prescreened to include only those that normally ate breakfast and liked chocolate. The bar used in this study contained 250 calories (about 30 more than most liquid diet shakes), 4 g dietary fiber, 14 g protein and 8 g fat. Subjects were instructed to consume the entire bar with a glass of water following an overnight fast when they would normally consume their first meal of the day and to assess their hunger on a 1 (not hungry at all) to 9 (as hungry as I have ever felt) scale before consumption, immediately after and hourly for 6 h (only on typical weekdays). Similar assessments were made for the perception of stomach fullness (1=empty, 9=extremely full), strength of the desire to eat (1=no desire, 9=extremely strong) and thirst (1=not at all thirsty, 9=extremely thirsty). One-hundred and eight subjects (23 male and 85 female) completed the study. No gender satiety differences were found. Hunger ratings and desire to eat remained significantly below baseline for 5 h following consumption. Stomach fullness scores were significantly above baseline for 5 h. Thirst scores were significantly below baseline for 3 h. In conclusion, although the meal replacement diet bars contained only 30 additional calories than liquids, they provided an additional 2 h of hunger suppression from baseline that may have an impact on overall weightloss success. These results support superior short-term hunger control with solid meal replacements.

  1. Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of China: A Multi-center Study

    Directory of Open Access Journals (Sweden)

    Hui-Jia Lin

    2015-01-01

    Full Text Available Background: With the progress of perinatal medicine and neonatal technology, more and more extremely low birth weight (ELBW survived all over the world. This study was designed to investigate the short-term outcomes of ELBW infants during their Neonatal Intensive Care Unit (NICU stay in the mainland of China. Methods: All infants admitted to 26 NICUs with a birth weight (BW < l000 g were included between January l, 2011 and December 31, 2011. All the data were collected retrospectively from clinical records by a prospectively designed questionnaire. The data collected from each NICU transmitted to the main institution where the results were aggregated and analyzed. Categorical variables were performed with Pearson Chi-square test. Binary Logistic regression analysis was used to detect risk factors. Results: A total of 258 ELBW infants were admitted to 26 NICUs, of whom the mean gestational age (GA was 28.1 ± 2.2 weeks, and the mean BW was 868 ± 97 g. The overall survival rate at discharge was 50.0%. Despite aggressive treatment 60 infants (23.3% died and another 69 infants (26.7% died after medical care withdrawal. Furthermore, the survival rate was significantly higher in coastal areas than inland areas (53.6% vs. 35.3%, P = 0.019. BW < 750 g and GA < 28 weeks were the largest risk factors, and being small for gestational age was a protective factor related to mortality. Respiratory distress syndrome was the most common complication. The incidence of patent ductus arteriosus, intraventricular hemorrhage, periventricular leukomalacia, bronchopulmonary dysplasia, retinopathy of prematurity was 26.2%, 33.7%, 6.7%, 48.1%, and 41.4%, respectively. Ventilator associated pneumonia was the most common hospital acquired infection during hospitalization. Conclusions: Our study was the first survey that revealed the present status of ELBW infants in the mainland of China. The mortality and morbidity of ELBW infants remained high as compared to other

  2. Mortality and Morbidity of Extremely Low Birth Weight Infants in the Mainland of China: A Multi-center Study

    Institute of Scientific and Technical Information of China (English)

    Hui-Jia Lin; Li-Zhong Du; Xiao-Lu Ma; Li-Ping Shi; Jia-Hua Pan; Xiao-Mei Tong; Qiu-Ping Li

    2015-01-01

    Background:With the progress ofperinatal medicine and neonatal technology,more and more extremely low birth weight (ELBW) survived all over the world.This study was designed to investigate the short-term outcomes of ELBW infants during their Neonatal Intensive Care Unit (NICU) stay in the mainland of China.Methods:All infants admitted to 26 NICUs with a birth weight (BW) <1000 g were included between January 1,2011 and December 3 1,201 1.All the data were collected retrospectively from clinical records by a prospectively designed questionnaire.The data collected from each NICU transmitted to the main institution where the results were aggregated and analyzed.Categorical variables were performed with Pearson Chi-square test.Binary Logistic regression analysis was used to detect risk factors.Results:A total of 258 ELBW infants were admitted to 26 NICUs,of whom the mean gestational age (GA) was 28.1 ± 2.2 weeks,and the mean BW was 868 ± 97 g.The overall survival rate at discharge was 50.0%.Despite aggressive treatment 60 infants (23.3%) died and another 69 infants (26.7%) died after medical care withdrawal.Furthermore,the survival rate was significantly higher in coastal areas than inland areas (53.6% vs.35.3%,P =0.019).BW <750 g and GA <28 weeks were the largest risk factors,and being small for gestational age was a protective factor related to mortality.Respiratory distress syndrome was the most common complication.The incidence of patent ductus arteriosus,intraventricular hemorrhage,periventricular leukomalacia,bronchopulmonary dysplasia,retinopathy of prematurity was 26.2%,33.7%,6.7%,48.1%,and 41.4%,respectively.Ventilator associated pneumonia was the most common hospital acquired infection during hospitalization.Conclusions:Our study was the first survey that revealed the present status of ELBW infants in the mainland of China.The mortality and morbidity of ELBW infants remained high as compared to other developed countries.

  3. Percutaneous evacuation of diffuse pulmonary interstitial emphysema by lung puncture in a baby with extremely low birth weight: a case report

    Directory of Open Access Journals (Sweden)

    Watanabe Masahiro

    2012-09-01

    Full Text Available Abstract Introduction Pulmonary interstitial emphysema is a serious complication of mechanical ventilation and can become life-threatening if progression occurs. Therapeutic lung puncture is a treatment option for severe pulmonary interstitial emphysema but has a limited use in babies with extremely low birth weight. We present a case of pulmonary interstitial emphysema in a Japanese baby (1-day-old boy with extremely low birth weight. The emphysema was successfully decompressed by therapeutic lung puncture performed with a trocar catheter. Case presentation The baby was born with a weight of 420g, which, to the best of our knowledge, is the lowest reported birth weight among babies with pulmonary interstitial emphysema. A chest X-ray on postnatal day 2 revealed pulmonary interstitial emphysema, which gradually progressed to diffuse pseudocystic changes. His condition became life-threatening despite the use of high-frequency oscillatory ventilation and lateral decubitus positioning. We evacuated the pulmonary interstitial emphysema by lung puncture with a trocar catheter to avoid respiratory and cardiovascular collapse. This resulted in adequate evacuation of the emphysema and a dramatic improvement in his clinical condition. Conclusions Therapeutic lung puncture performed with a trocar catheter is beneficial in babies with extremely low birth weight and diffuse pulmonary interstitial emphysema. This treatment option may be broadly applicable, especially in an emergency situation.

  4. Growth and Development in Extremely Low Birth Weight Infants After the Introduction of Exclusive Human Milk Feedings.

    Science.gov (United States)

    Colacci, Michael; Murthy, Karna; DeRegnier, Raye-Ann O; Khan, Janine Y; Robinson, Daniel T

    2017-01-01

    Objective To estimate associations of exclusive human milk (EHM) feedings with growth and neurodevelopment through 18 months corrected age (CA) in extremely low birth weight (ELBW) infants. Study Design ELBW infants admitted from July 2011 to June 2013 who survived were reviewed. Infants managed from July 2011 to June 2012 were fed with bovine milk-based fortifiers and formula (BOV). Beginning in July 2012, initial feedings used a human milk-based fortifier to provide EHM feedings. Infants were grouped on the basis of feeding regimen. Primary outcomes were the Bayley-III cognitive scores at 6, 12, and 18 months and growth. Results Infants (n = 85; 46% received EHM) were born at 26 ± 1.9 weeks (p = 0.92 between groups) weighing 776 ± 139 g (p = 0.67 between groups). Cognitive domain scores were similar at 6 months (BOV: 96 ± 7; EHM: 95 ± 14; p = 0.70), 12 months (BOV: 97 ± 10; EHM: 98 ± 9; p = 0.86), and 18 months (BOV: 97 ± 16; EHM: 98 ± 14; p = 0.71) CA. Growth velocity prior to discharge (BOV: 12.1 ± 5.2 g/kg/day; EHM: 13.1 ± 4.0 g/kg/day; p = 0.33) and subsequent growth was similar between groups. Conclusion EHM feedings appear to support similar growth and neurodevelopment in ELBW infants as compared with feedings containing primarily bovine milk-based products.

  5. Controls on Extreme Droughts and Adaptation Strategies in Semiarid Regions

    Science.gov (United States)

    Scanlon, B. R.; Cook, C.; Fernando, D. N.; LeBlanc, M.

    2012-12-01

    Increasing vulnerability to droughts with reduced per capita water storage, particularly in semiarid regions, underscores the need for predictive understanding of drought controls and development of adaptation strategies for water resources management. In this study we evaluate causes of major droughts in southwest and southcentral US (California and Texas) and southeast Australia (Murray Darling Basin). Impacts of climate cycles (ENSO, PDO, AMO, NAO, IOD) and atmospheric circulation on drought initiation and persistence are examined. Effects of drought on surface water reservoir storage, groundwater storage, irrigation, and crop production are compared. Adaptation strategies being evaluated include water transfers among sectors, particularly from irrigated agriculture to other groups, increasing storage using managed aquifer recharge, water reuse, and development of new water sources (e.g. seawater desalination). It is critical to develop a broad portfolio of water sources to increase resilience to future droughts.

  6. The role of vision in obese and normal-weight children's gait control.

    Science.gov (United States)

    D'Hondt, Eva; Segers, Veerle; Deforche, Benedicte; Shultz, Sarah P; Tanghe, Ann; Gentier, Ilse; De Bourdeaudhuij, Ilse; De Clercq, Dirk; Lenoir, Matthieu

    2011-02-01

    Previous research has suggested that perceptual-motor difficulties may account for obese children's lower motor competence; however, specific evidence is currently lacking. Therefore, this study examined the effect of altered visual conditions on spatiotemporal and kinematic gait parameters in obese versus normal-weight children. Thirty-two obese and normal-weight children (11.2±1.5 years) walked barefoot on an instrumented walkway at constant self-selected speed during LIGHT and DARK conditions. Three-dimensional motion analysis was performed to calculate spatiotemporal parameters, as well as sagittal trunk segment and lower extremity joint angles at heel-strike and toe-off. Self-selected speed did not significantly differ between groups. In the DARK condition, all participants walked at a significantly slower speed, decreased stride length, and increased stride width. Without normal vision, obese children had a more pronounced increase in relative double support time compared to the normal-weight group, resulting in a significantly greater percentage of the gait cycle spent in stance. Walking in the DARK, both groups showed greater forward tilt of the trunk and restricted hip movement. All participants had increased knee flexion at heel-strike, as well as decreased knee extension and ankle plantarflexion at toe-off in the DARK condition. The removal of normal vision affected obese children's temporal gait pattern to a larger extent than that of normal-weight peers. Results suggest an increased dependency on vision in obese children to control locomotion. Next to the mechanical problem of moving excess mass, a different coupling between perception and action appears to be governing obese children's motor coordination and control.

  7. Weight management using the internet: A randomized controlled trial

    Science.gov (United States)

    Most weight-loss research targets obese individuals who desire large weight reductions. However, evaluation of weight-gain prevention in overweight individuals is also critical as most Americans become obese as a result of a gradual gain of 1-2 pounds per year over many years. This study evaluated t...

  8. Multimodal Discrimination of Schizophrenia Using Hybrid Weighted Feature Concatenation of Brain Functional Connectivity and Anatomical Features with an Extreme Learning Machine

    Directory of Open Access Journals (Sweden)

    Muhammad Naveed Iqbal Qureshi

    2017-09-01

    Full Text Available Multimodal features of structural and functional magnetic resonance imaging (MRI of the human brain can assist in the diagnosis of schizophrenia. We performed a classification study on age, sex, and handedness-matched subjects. The dataset we used is publicly available from the Center for Biomedical Research Excellence (COBRE and it consists of two groups: patients with schizophrenia and healthy controls. We performed an independent component analysis and calculated global averaged functional connectivity-based features from the resting-state functional MRI data for all the cortical and subcortical anatomical parcellation. Cortical thickness along with standard deviation, surface area, volume, curvature, white matter volume, and intensity measures from the cortical parcellation, as well as volume and intensity from sub-cortical parcellation and overall volume of cortex features were extracted from the structural MRI data. A novel hybrid weighted feature concatenation method was used to acquire maximal 99.29% (P < 0.0001 accuracy which preserves high discriminatory power through the weight of the individual feature type. The classification was performed by an extreme learning machine, and its efficiency was compared to linear and non-linear (radial basis function support vector machines, linear discriminant analysis, and random forest bagged tree ensemble algorithms. This article reports the predictive accuracy of both unimodal and multimodal features after 10-by-10-fold nested cross-validation. A permutation test followed the classification experiment to assess the statistical significance of the classification results. It was concluded that, from a clinical perspective, this feature concatenation approach may assist the clinicians in schizophrenia diagnosis.

  9. Robot-Environment Interaction Control of a Flexible Joint Light Weight Robot Manipulator

    Directory of Open Access Journals (Sweden)

    Genliang Xiong

    2012-09-01

    Full Text Available This paper presents a weighted path planning approach for a light weight robot coming into compliant contact with the environment, as well as robot‐environment interaction enabled impedance control. Using a joint torque sensor, Cartesian impedance control is introduced to realize the manipulator compliance control. Then the weighted path planning approach is developed to detect the contact condition and to control the interaction. Experiments are carried out on a 5‐DOF light weight manipulator. The experimental results validate the developed control approach enhanced by the weighted path planning scheme.

  10. Influence of ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms on body weight and body composition changes after a controlled weight-loss intervention

    National Research Council Canada - National Science Library

    Cupeiro, Rocío; Wang, Guan; Amigo, Teresa; Gomez-Candela, Carmen; Szendrei, Barbara; Calderón, Francisco J; Benito, Pedro J; González-Lamuño, Domingo; Pitsiladis, Yannis

    2016-01-01

    ...) polymorphisms on weight loss remain controversial. The aim of this study was to investigate the effect of these polymorphisms on changes in weight and body composition during a controlled weight-loss program...

  11. Overweight Adolescents’ Self-Perceived Weight and Weight Control Behaviour: HBSC Study in Finland 1994–2010

    Directory of Open Access Journals (Sweden)

    Kristiina Ojala

    2012-01-01

    Full Text Available Introduction. Overweight and perception of being overweight, may lead adolescent to lose weight. The aim of the present study was to investigate overweight adolescents’ self-perceived weight, body dissatisfaction, and weight control behaviour during 1994–2010 in Finland. Methods. The country-representative, cross-sectional data of 15-year olds were obtained from the Health Behaviour in School-aged Children (HBSC study, conducted in 1994 (=1194; males: 48%, 1998 (=1545; 49%, 2002 (=1745; 50%, 2006 (=1670; 47%, and 2010 (=2082; 48%. Results. The majority of overweight boys (62–69% and girls (89–100% assessed themselves as too fat, and their body image was lower than in nonoverweight adolescents. The highest prevalence of current weight controlling was found in 2006 in males (18% and in 2010 in females (39%. Conclusion. The phenomena were current and gender differences notable, but there was no statistically significant difference in overweight adolescents’ self-perceived weight, body dissatisfaction, or weight control behaviour between survey years.

  12. Binge Eating and Weight Control: The Role of Experiential Avoidance

    Science.gov (United States)

    Lillis, Jason; Hayes, Steven C.; Levin, Michael E.

    2011-01-01

    Two thirds of the adults in the United States are overweight or obese. Binge eating is a barrier to treatment adherence and sustained weight loss, and can be seen as a form of experiential avoidance. The current study analyzed the impact of binge eating on weight reduction in a previously published study of a 1-day acceptance and commitment…

  13. Body size perception and weight control in youth

    DEFF Research Database (Denmark)

    Quick, V; Nansel, T R; Liu, D

    2014-01-01

    OBJECTIVES: To examine 9-year trends and relationships regarding misperceptions of body size and dieting for weight loss among adolescents from 24 countries, and explore the influence of country-level overweight prevalence. METHODS: Sociodemographic characteristics, body size perception and dieti......, suggesting a potentially stronger impact of social comparison on weight-related perceptions than on behavior.......OBJECTIVES: To examine 9-year trends and relationships regarding misperceptions of body size and dieting for weight loss among adolescents from 24 countries, and explore the influence of country-level overweight prevalence. METHODS: Sociodemographic characteristics, body size perception and dieting......, underestimation of body size in overweight adolescents, dieting for weight loss in non-overweight and overweight adolescents and relationships between body size perception and dieting. Analyses were stratified by weight status and sex. Covariates included country-level overweight prevalence, family affluence...

  14. Treadmill training with partial body-weight support after anterior cruciate ligament reconstruction: a randomized controlled trial

    Science.gov (United States)

    luo, Yuan; Shen, Weizhong; Jiang, Zhong; Sha, Jiao

    2016-01-01

    [Purpose] To compare the effects of treadmill training with partial body weight support (TTPBWS) and conventional physical therapy (PT) on subjects with anterior cruciate ligament reconstructions. [Subjects and Methods] A total of 40 subjects were randomly allocated to either a treatment group or a control group. Subjects received either treadmill training with partial body weight support (treatment group) or conventional physical therapy (control group). The circumferences of the lower extremities, Holden classifications, 10-meter walking times and the International Knee Documentation Committee (IKDC) scores were compared at 12 and 24 weeks post-operation. The knee joint stability was tested at 24 weeks post-operation using a KT-1000. [Results] Significant differences were found between the two groups at the 12 weeks post-operation. For most of the measures, there was no significant difference between the groups at 24 weeks post-operation. Interestingly, for most of the measures, there was no significant difference between their values in the treatment group at 12 weeks and their values in the control group at 24 weeks post-operation. [Conclusion] The function of a subject’s lower extremities can be improved and the improvement was clearly accelerated by the intervention of treadmill training with partial body weight support, without compromising the stability of the knee joints in a given follow-up period. PMID:28174445

  15. The effects of a 12-week program of static upper extremity weight bearing exercises on weight bearing in children with hemiplegic type of cerebral palsy

    Directory of Open Access Journals (Sweden)

    P. Jayaraman

    2010-02-01

    Full Text Available The  major  objective  of  this  study  was  to  quantify  the  effects  of a  12-week  program  of  weight  bearing  exercises  on  weight  borne  through  the hand and grip pressures in children with hemiplegic cerebral palsy. This study also sought to monitor the change in spasticity immediately following weight-bearing  exercises.  A  quasi-experimental,  one  group  pre-test,  post-test  study  was used. Eleven children with hemiplegic type of cerebral palsy from a special school in KwaZulu Natal participated after fully informed written consent. The intervention consisted of a 12-week program of weight bearing. The Tekscan Grip system was used to quantify weight borne through the hand during extended arm prone and quadruped positions and whilst holding a pencil and a tumbler. The modified Ashworth grading of spasticity was used to monitor spasticity. The data was analysed using the random effects GLS model Wald Chi Square test. Significant increases in contact pressure in extended arms prone (p=0,012 and quadruped (p=0,002 and when holding a pencil (p=0,045 was noted post-test compared to pre-test. Significant increases in contact area of the hand was also noted in prone (p=0,000, quadruped (p=0, 03 at assessment 7 and when holding a pencil (p=0,035.  A significant decrease in spasticity during elbow extension (p=0,004, and wrist flexion (p=0,026 and extension (p=0,004 was noted. An overall significant effect of static weight bearing exercises on weight borne through the hands, grip strength and spasticity justifies the use of static weight-bearing in therapy.

  16. Intention, perceived control, and weight loss: an application of the theory of planned behavior.

    Science.gov (United States)

    Schifter, D E; Ajzen, I

    1985-09-01

    Success at attempted weight reduction among college women was predicted on the basis of a theory of planned behavior. At the beginning of a 6-week period, participants expressed their attitudes, subjective norms, perceived control, and intentions with respect to losing weight. In addition, the extent to which they had made detailed weight reduction plans was assessed, as were a number of general attitudes and personality factors. In support of the theory, intentions to lose weight were accurately predicted on the basis of attitudes, subjective norms, and perceived control; perceived control and intentions were together moderately successful in predicting the amount of weight that participants actually lost over the 6-week period. Actual weight loss was also found to increase with development of a plan and with ego strength, factors that were assumed to increase control over goal attainment. Other factors, such as health locus of control, perceived competence, and action control, were found to be unrelated to weight reduction.

  17. Overweight Perception: Associations with Weight Control Goals, Attempts, and Practices among Chinese Female College Students.

    Science.gov (United States)

    Tanenbaum, Hilary C; Felicitas, Jamie Q; Li, Yawen; Tobias, Malaika; Chou, Chih-Ping; Palmer, Paula H; Spruijt-Metz, Donna; Reynolds, Kim D; Anderson Johnson, C; Xie, Bin

    2016-03-01

    Concurrent with the dramatic cultural and economic shifts occurring as mainland China becomes increasingly "Westernized," the weight perceptions, ideal body weight, and weight management goals and practices of Chinese females have also undergone significant changes. To investigate relationships between overweight status, weight perception patterns, and weight management goals and practices in Chinese female college students. A cross-sectional analysis was conducted with data from 902 female subjects aged 18 to 25 years participating in the China Seven Cities Study, a health promotion and smoking prevention study conducted in mainland China in 2003. Logistic regression models were used to explore associations between overweight status, weight perception, specific weight management goals and practices, and current levels of vigorous-intensity physical activity and food consumption. Based on World Health Organization standards for Asian adults, 16.7% of college females were overweight or obese, although 50.8% considered themselves to be "too heavy." Among participants perceiving themselves as overweight (n=458), 69.2% (n=371) were inaccurate and did not meet criteria for overweight or obese. The percentage of participants attempting weight loss was 48.2%, and 33.1% wanted to maintain their current weight. Attempts to lose or maintain weight were related to actual and perceived weight status, but not to increased vigorous-intensity physical activity or fruit and vegetable intake, nor to decreased consumption of sweets, soda, Western fast foods, and fried foods. Only 21.5% of participants desiring weight loss or maintenance reported using a combination of vigorous-intensity physical activity and a reduced-fat and -calorie diet, whereas 20.2% tried extreme methods such as fasting, using diet pills, vomiting, or smoking. Our findings underscore the need to promote healthy weight management practices among Chinese female college students, with an emphasis on diet and

  18. Upper Extremity Artificial Limb Control as an Issue Related to Movement and Mobility in Daily Living

    Science.gov (United States)

    Wallace, Steve; Anderson, David I.; Trujillo, Michael; Weeks, Douglas L.

    2005-01-01

    The 1992 NIH Research Planning Conference on Prosthetic and Orthotic Research for the 21st Century (Childress, 1992) recognized that the field of prosthetics lacks theoretical understanding and empirical studies on learning to control an upper-extremity prosthesis. We have addressed this problem using a novel approach in which persons without…

  19. Design of PID Controller for Maglev System Based on an Improved PSO with Mixed Inertia Weight

    Directory of Open Access Journals (Sweden)

    Rongrong Song

    2014-06-01

    Full Text Available A Maglev system was modeled by the exact feedback linearization to achieve two same linear subsystems. The proportional-integral-differential controllers (PID based on particle swarm optimization (PSO algorithm with four different inertia weights were then used to regulate both linear subsystems. These different inertia weights were Fixed Inertia Weight (FIW, Linear Descend Inertia Weight (LIW, Linear Differential Descend Inertia Weight (LDW, and mixed inertia weight (FIW–LIW-LDW. On the other hand, the parameters  of the PSO-PID controllers via mixed inertia weight (FIW–LIW-LDW were optimized, the parameter values  in the electromagnet 1 and electromagnet 2 were both 0.4. Simulation results demonstrate that the control performance and robustness of PSO-PID based on mixed inertia weight (FIW–LIW-LDW was superior to that of three PSO-PID controllers based on single inertia weights. For electromagnet 1, the overshoot of PSO-PID controller with mixed inertia weight reduced 3.36% than that of PSO-PID controller with FIW, 5.81% than that of PSO-PID controller with LIW, and 6.34% than that of PSO-PID controller with LDW; for electromagnet 2, the overshoot of PSO-PID controller with mixed inertia weight reduced 1.07% than that of PSO-PID controller with FIW, 12.56% than that of PSO-PID controller with LIW, 7.97% than that of PSO-PID controller with LDW; the adjusting time of PSO-PID controller with mixed inertia weight reduced 0.395s than that of PSO-PID controller with FIW, 34.1s than that of PSO-PID controller with LIW, and 33.494s than that of PSO-PID controller with LDW

  20. Preventing weight gain: the baseline weight related behaviors and delivery of a randomized controlled intervention in community based women

    Directory of Open Access Journals (Sweden)

    Teede Helena J

    2009-01-01

    Full Text Available Abstract Background Women aged 25–45 years represent a high risk group for weight gain and those with children are at increased risk because of weight gain associated with pregnancy and subsequent lifestyle change. Average self-reported weight gain is approximately 0.60 kg per year, and weight gain is associated with increased risk of chronic disease. There are barriers to reaching, engaging and delivering lifestyle interventions to prevent weight gain in this population. Methods This study investigated the baseline weight related behaviors and feasibility of recruiting and delivering a low intensity self-management lifestyle intervention to community based women with children in order to prevent weight gain, compared to standard education. The recruitment and delivery of the cluster-randomized controlled intervention was in conjunction with 12 primary (elementary schools. Baseline data collection included demographic, anthropometric, behavioral and biological measures. Results Two hundred and fifty community based women were randomized as clusters to intervention (n = 127 or control (n = 123. Mean age was 40.4 years (SD 4.7 and mean BMI 27.8 kg/m2 (SD 5.6. All components of this intervention were successfully delivered and retention rates were excellent, 97% at 4 months. Nearly all women (90% reported being dissatisfied with their weight and 72% attempted to self-manage their weight. Women were more confident of changing their diet (mean score 3.2 than physical activity (mean score 2.7. This population perceived they were engaging in prevention behaviors, with 71% reporting actively trying to prevent weight gain, yet they consumed a mean of 68 g fat/day (SD30 g and 27 g saturated fat/day (SD12 g representing 32% and 13% of energy respectively. The women had a high rate of dyslipidemia (33% and engaged in an average of 9187 steps/day (SD 3671. Conclusion Delivery of this low intensity intervention to a broad cross-section of community based

  1. Sizing Up Peers: Adolescent Girls’ Weight Control and Social Comparison in the School Context *

    Science.gov (United States)

    Mueller, Anna S.; Pearson, Jennifer; Muller, Chandra; Frank, Kenneth; Turner, Alyn

    2014-01-01

    Using the National Longitudinal Study of Adolescent Health and multi-level modeling, we examine the role of social comparison with schoolmates in adolescent girls’ weight control. Specifically, we focus on how girls’ own weight control is influenced by the body sizes and weight-control behaviors of their schoolmates. Our findings suggest that comparisons with similar others (in this case, girls of a similar body size) appears to have the strongest association with individual girls’ reports of trying to lose weight. For example, the odds than an overweight girl is engaged in weight control increases substantially when many overweight girls in her school are also trying to lose weight. This study highlights how schools play an important role in shaping girls’ decisions to practice weight control and demonstrates how social comparison theory improves our understanding of how health behaviors are linked to social contexts. PMID:20420295

  2. Significant progression of load on the musculoskeletal system with extremely high loads, with rapid weekly weight gains, using the Anatoly Gravitational System, in a 10-week training period

    Directory of Open Access Journals (Sweden)

    Burke DT

    2013-10-01

    Full Text Available David T Burke,1 David Tran,1 Di Cui,1 Daniel P Burke,2 Samir Al-Adawi,3 Atsu SS Dorvlo41Emory University Medical School, Atlanta, GA, USA; 2Georgia College and State University, GA, USA; 3Department of Behavioral Medicine, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman; 4Department of Mathematics and Statistics, College of Science, Sultan Qaboos University, Muscat, OmanAbstract: In an age of increasing numbers of lifestyle diseases and plasticity of longevity, exercise and weight training have been increasingly recognized as both preventing and mitigating the severity of many illnesses. This study was designed to determine whether significant weight-lifting gains could be realized through the Anatoly Gravitational System. Specifically, this study sought to determine whether this once-weekly weight-training system could result in significant weekly strength gains during a 10-week training period. A total of 50 participants, ranging in age from 17 to 67 years, completed at least 10 weekly 30-minute training sessions. The results suggest participants could, on average, double their weight-lifting capacity within 10 sessions. This preliminary study, which would require further scrutiny, suggests the Anatoly Gravitational System provides a rather unique opportunity to load the musculoskeletal system with extremely high loads, with rapid weekly weight gains, using only short weekly training sessions. More studies are warranted to scrutinize these findings.Keywords: Anatoly Gravitational System, weight training, musculoskeletal system

  3. Design issues for the active control system of the California Extremely Large Telescope (CELT)

    Science.gov (United States)

    Chanan, Gary A.; Nelson, Jerry E.; Ohara, Catherine M.; Sirko, Edwin

    2000-08-01

    We explore the issues in the control and alignment of the primary mirror of the proposed 30 meter California Extremely Large Telescope and other very large telescopes with segmented primaries (consisting of 1000 or more segments). We show that as the number of segments increases, the noise in the telescope active control system (ACS) increases, roughly as (root)n. This likely means that, for a thousand segment telescope like CELT, Keck-style capacitive sensors will not be able to adequately monitor the lowest spatial frequency degrees of freedom of the primary mirror, and will therefore have to be supplemented by a Shack-Hartmann-type wavefront sensor. However, in the case of segment phasing, which is governed by a `control matrix' similar to that of the ACS, the corresponding noise is virtually independent of n. It follows that reasonably straightforward extensions of current techniques should be adequate to phase the extremely large telescopes of the future.

  4. 76 FR 12916 - Benzocaine; Weight Control Drug Products for Over-the-Counter Human Use

    Science.gov (United States)

    2011-03-09

    ... benzocaine be classified as nonmonograph at any concentration for use in OTC weight control drug products... daily) Group 4: Glucose hard candy containing benzocaine, caffeine, and vitamins (benzocaine...

  5. Load control and the provision of the efficiency of steam boilers equipped with an extremal governor

    Science.gov (United States)

    Sabanin, V. P.; Kormilitsyn, V. I.; Kostyk, V. I.; Smirnov, N. I.; Koroteev, A. V.; Repin, A. I.

    2014-12-01

    This paper presents an analysis of main problems of controlling small- and medium-size steam boilers. Noted are deficiencies of current normative and technical documents, as well as those of the traditional concept of the process of fuel firing, the methods for and algorithms of boiler control. There is established an approach to creation of such control systems in which a boiler is treated, as to control and load channels, as a nonlinear linked controlled objects. To control load and efficiency of a boiler, an universal schematic diagram is suggested that allows for the possibility of implementation in modern controllers of both known methods and a new method using an extremal governor, which would provide minimum fuel consumption at given thermal load of a boiler.

  6. Based on the SPSS Software t+ of Weight Control on Taekwondo Athletes' Body Function Influence Research

    Directory of Open Access Journals (Sweden)

    Mingming Guo

    2013-04-01

    Full Text Available Weight control has become the ideal level of Taekwondo athletes participate in the competition the important method. According to the nine elite Taekwondo athletes as the research samples, research mainly by using the method of experiments, the experiments were carried out at six weeks, 1 times a week to sweat ion and the anaerobic capacity test and the four body fat content of the test, t test method for analysis of pre-race weight control on Athletes' body function influence. Results showed that, after a period of six weeks after the athlete's weight control, were highly significant changes in weight control; from the beginning of the third week, athlete's body weight and body fat content began to drop dramatically; through the test showed the percentage of body fat and lean body mass were decreased significantly; the anaerobic exercise capacity in athletes the weight control period was not changed significantly; from the beginning of the third week athletes sweat sodium and calcium ion concentration increased significantly, while carbon dioxide binding force is greatly reduced, until the end of sixth week weight control. By the appropriate increase in relaxation time and increase training of aerobic training proportion, can realize the athletes in weight control process to consume fat goal primarily, can provide excellent athletes to provide beneficial reference for weight control research.

  7. Pericardial Effusion and Cardiac Tamponade Following Percutaneously Inserted Central Line Insertion in an Extremely Low-birth-weight Baby: Case Report and Successful Management

    Science.gov (United States)

    Desai, Avinash V.; Kumar, Abnish; Shanbhag, Praful; Shah, Forum

    2017-01-01

    Pericardial effusion and cardiac tamponade are rare complications of percutaneously inserted central lines (PICLs), in extremely low-birth-weight babies. This particular complication carries a high degree of mortality, if not suspected and diagnosed. Bedside echocardiography proves not only diagnostic but also can be lifesaving in these conditions. Here, we wish to report such a baby who suddenly deteriorated and showed cardiovascular instability 2 days after the insertion of PICL. Immediate bedside echocardiography helped pick up the effusion which was drained using a subxiphoid percutaneous approach. PMID:28197055

  8. Como minimizar a lesão pulmonar no prematuro extremo: propostas Strategies to minimize lung injury in extremely low birth weight infants

    Directory of Open Access Journals (Sweden)

    Cleide Suguihara

    2005-03-01

    Full Text Available OBJETIVO: Apresentar uma revisão das principais causas da nova displasia broncopulmonar e as estratégias utilizadas para diminuir sua incidência nos prematuros extremos. FONTES DOS DADOS: Para essa revisão, pesquisas foram feitas na MEDLINE (1996 a outubro de 2004, no Cochrane Database, em resumos da Society for Pediatric Research e recentes conferências sobre o tema. SÍNTESE DOS DADOS: A tecnologia e os novos conhecimentos científicos têm aumentado significantemente a sobrevida de prematuros extremos. Esse aumento da sobrevida resultou em aumento da incidência de displasia broncopulmonar. Atualmente, a displasia broncopulmonar é mais freqüentemente observada em recém-nascidos OBJECTIVE: To review the main causes of new bronchopulmonary dysplasia and the strategies utilized to decrease its incidence in extremely low birth weight infants. DATA SOURCES: For this review a MEDLINE search from 1966 to October 2004, the Cochrane Database, abstracts from the Society for Pediatric Research and recent meetings on the topic were used. SUMMARY OF FINDINGS: The survival of extremely low birth weight infants has increased significantly due to improvement in both scientific knowledge and technology. This improvement in survival has therefore resulted in an increased incidence of bronchopulmonary dysplasia. The characteristics of bronchopulmonary dysplasia in extremely low birth weight infants, the so called "new" bronchopulmonary dysplasia are quite different from the classic bronchopulmonary dysplasia described by Northway. This new bronchopulmonary dysplasia has a multifactorial etiology, which includes volutrauma, atelectrauma, oxygen toxicity and lung inflammation. Therapy such as prenatal corticosteroids, exogenous surfactant, nasal continuous positive airway pressure, new mechanical ventilation modalities and gentle ventilation have been used in attempts to decrease lung injury severity. CONCLUSIONS: In order to prevent lung injury in

  9. Physical activity intensity and weight control status among U.S. Adults with diabetes.

    Science.gov (United States)

    Loprinzi, Paul D; Pariser, Gina

    2014-01-01

    We have a limited understanding of the objectively determined physical activity levels by weight control status (i.e., trying to lose weight, trying to maintain weight, and neither trying to lose or maintain weight) among U.S. adults with diabetes. Therefore, this study assessed the association between physical activity and weight control status among U.S. adults with diabetes. Cross-sectional survey. The 2003-2006 National Health and Nutrition Examination Survey (NHANES) was used, which is representative of the U.S. population. Subjects were 733 adults (≥20 years) with diabetes. Participants wore an accelerometer to assess physical activity, and questionnaires were used to assess weight control status and covariates. Multivariate negative binomial regressions were used. After adjustments, and compared to those not trying to lose or maintain their weight, women trying to lose weight engaged in 74% more physical activity (rate ratio = 1.74; 95% confidence interval [CI]: 1.14 to 2.65). Although findings were not significant for men, men were more likely than women to meet physical activity recommendations. Diabetic women trying to lose weight engaged in more physical activity than did their female counterparts not trying to lose or maintain their weight. Although men were more active than women, no differences in activity estimates occurred across weight control status for men.

  10. Functional brain response to food images in successful adolescent weight losers compared with normal-weight and overweight controls.

    Science.gov (United States)

    Jensen, Chad D; Kirwan, C Brock

    2015-03-01

    Research conducted with adults suggests that successful weight losers demonstrate greater activation in brain regions associated with executive control in response to viewing high-energy foods. No previous studies have examined these associations in adolescents. Functional neuroimaging was used to assess brain response to food images among groups of overweight (OW), normal-weight (NW), and successful weight-losing (SWL) adolescents. Eleven SWL, 12 NW, and 11 OW participants underwent functional magnetic resonance imaging while viewing images of high- and low-energy foods. When viewing high-energy food images, SWLs demonstrated greater activation in the dorsolateral prefrontal cortex (DLPFC) compared with OW and NW controls. Compared with NW and SWL groups, OW individuals demonstrated greater activation in the ventral striatum and anterior cingulate in response to food images. Adolescent SWLs demonstrated greater neural activation in the DLPFC compared with OW/NW controls when viewing high-energy food stimuli, which may indicate enhanced executive control. OW individuals' brain responses to food stimuli may indicate greater reward incentive processes than either SWL or NW groups. © 2015 The Obesity Society.

  11. The effect of effort and weight controllability on perceptions of obese individuals.

    Science.gov (United States)

    Black, Melissa J; Sokol, Nicole; Vartanian, Lenny R

    2014-01-01

    We examined the impact of offset controllability (capability of losing weight) and offset effort (efforts to lose weight) on judgments of an obese target. Participants (n = 216) read about an obese person whose body weight was controllable/uncontrollable, and who did/did not put in effort to eat healthily and exercise. Effort played a more important role than controllability in evaluations of the target. Targets who put in effort to be healthy were ascribed fewer obesity stereotypes, evoked less disgust, and were considered to have a more acceptable lifestyle. These findings extend attribution theory and have implications for strategies to reduce weight bias.

  12. Friendship clique and peer influences on body image concerns, dietary restraint, extreme weight-loss behaviors, and binge eating in adolescent girls.

    Science.gov (United States)

    Paxton, S J; Schutz, H K; Wertheim, E H; Muir, S L

    1999-05-01

    This study explored friendship variables in relation to body image, dietary restraint, extreme weight-loss behaviors (EWEBs), and binge eating in adolescent girls. From 523 girls, 79 friendship cliques were identified using social network analysis. Participants completed questionnaires that assessed body image concerns, eating, friendship relations, and psychological family, and media variables. Similarity was greater for within than for between friendship cliques for body image concerns, dietary restraint, and EWLBs, but not for binge eating. Cliques high in body image concerns and dieting manifested these concerns in ways consistent with a high weight/shape-preoccupied subculture. Friendship attitudes contributed significantly to the prediction of individual body image concern and eating behaviors. Use of EWLBs by friends predicted an individual's own level of use.

  13. Introduction of percutaneous-tunneled transfontanellar external ventricular drainage in the management of hydrocephalus in extremely low-birth-weight infants.

    Science.gov (United States)

    Zucchelli, Mino; Lefosse, Mariella; Corvaglia, Luigi; Martini, Silvia; Sandri, Fabrizio; Soffritti, Silvia; Ancora, Gina; Mammoliti, Palma; Gargano, Giancarlo; Galassi, Ercole

    2016-07-01

    OBJECTIVE Hydrocephalus treatment in extremely low-birth-weight (ELBW) infants still represents a challenge for the pediatric neurosurgeon, particularly when the patient weighs far less than 1000 g. In such cases, the benefits in terms of neurological outcome following early treatment do not always outweigh the surgical risks, especially considering the great difference in the surgical risk before patient weight increases. To assess the efficacy and reliability of a percutaneous-tunneled, transfontanellar external ventricular drain (PTTEVD) in ELBW infants, the authors started a new protocol for the early surgical treatment of hydrocephalus. METHODS Ten cases of posthemorrhagic hydrocephalus (PHH) in ELBW infants (5 cases introduction of PTTEVD placement in our standard protocol for the management of PHH has proved to be a wise option for small patients.

  14. A neurocognitive approach for recovering upper extremity movement following subacute stroke: a randomized controlled pilot study.

    Science.gov (United States)

    Sallés, Laia; Martín-Casas, Patricia; Gironès, Xavier; Durà, María José; Lafuente, José Vicente; Perfetti, Carlo

    2017-04-01

    [Purpose] This study aims to describe a protocol based on neurocognitive therapeutic exercises and determine its feasibility and usefulness for upper extremity functionality when compared with a conventional protocol. [Subjects and Methods] Eight subacute stroke patients were randomly assigned to a conventional (control group) or neurocognitive (experimental group) treatment protocol. Both lasted 30 minutes, 3 times a week for 10 weeks and assessments were blinded. Outcome measures included: Motor Evaluation Scale for Upper Extremity in Stroke Patients, Motricity Index, Revised Nottingham Sensory Assessment and Kinesthetic and Visual Imagery Questionnaire. Descriptive measures and nonparametric statistical tests were used for analysis. [Results] The results indicate a more favorable clinical progression in the neurocognitive group regarding upper extremity functional capacity with achievement of the minimal detectable change. The functionality results are related with improvements on muscle strength and sensory discrimination (tactile and kinesthetic). [Conclusion] Despite not showing significant group differences between pre and post-treatment, the neurocognitive approach could be a safe and useful strategy for recovering upper extremity movement following stroke, especially regarding affected hands, with better and longer lasting results. Although this work shows this protocol's feasibility with the panel of scales proposed, larger studies are required to demonstrate its effectiveness.

  15. Expert Panel Consensus for and Analysis of Key Attributes on Websites Devoted to Weight Control

    Science.gov (United States)

    Brown, Stephen L.; Land, Diane; Johnson, Chandrika; Miller, Kim

    2014-01-01

    Background: Obesity presents major challenges to public health in the United States. Trials of web-based interventions for weight control suggest that the Internet is a promising option for program delivery. Purpose: This study sought consensus among experts regarding critical components of successful weight control and to systematically examine…

  16. Control of molecular rotation in the limit of extreme rotational excitation

    CERN Document Server

    Milner, V

    2015-01-01

    Laser control of molecular rotation is an area of active research. A number of recent studies has aimed at expanding the reach of rotational control to extreme, previously inaccessible rotational states, as well as controlling the directionality of molecular rotation. Dense ensembles of molecules undergoing ultrafast uni-directional rotation, known as molecular superrotors, are anticipated to exhibit unique properties, from spatially anisotropic diffusion and vortex formation to the creation of powerful acoustic waves and tuneable THz radiation. Here we describe our recent progress in controlling molecular rotation in the regime of high rotational excitation. We review two experimental techniques of producing uni-directional rotational wave packets with a "chiral train" of femtosecond pulses and an "optical centrifuge". Three complementary detection methods, enabling the direct observation, characterization and control of the superrotor states, are outlined: the one based on coherent Raman scattering, and two...

  17. Rheological Properties of Extreme Pressure Greases Measured Using a Process Control Rheometer

    DEFF Research Database (Denmark)

    Glasscock, Julie; Smith, Robin S.

    2012-01-01

    A new process control rheometer (PCR) designed for use in industrial process flows has been used to measure the rheological properties of three extreme-pressure greases. The rheometer is a robust yet sensitive instrument designed to operate in an industrial processing environment in either in......-line or on-line configurations. The PCR was able to measure the rheological properties including the elastic modulus, viscous modulus, and complex viscosity of the greases which in an industrial flow application could be used as variables in a feedback system to control the process and the quality...

  18. Controlling silk fibroin microspheres via molecular weight distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zeng, Dong-Mei; Pan, Jue-Jing; Wang, Qun; Liu, Xin-Fang; Wang, Hui [National Engineering Laboratory for Modern Silk, College for Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215123 (China); Zhang, Ke-Qin, E-mail: kqzhang@suda.edu.cn [National Engineering Laboratory for Modern Silk, College for Textile and Clothing Engineering, Soochow University, Suzhou, Jiangsu 215123 (China); Research Center of Cooperative Innovation for Functional Organic/Polymer Material Micro/Nanofabrication, Soochow University, Suzhou, Jiangsu 215123 (China)

    2015-05-01

    Silk fibroin (SF) microspheres were produced by salting out SF solution via the addition of potassium phosphate buffer solution (K{sub 2}HPO{sub 4}–KH{sub 2}PO{sub 4}). The morphology, size and polydispersity of SF microspheres were adjusted by changing the molecular weight (MW) distribution and concentration of SF, as well as the ionic strength and pH of the buffer solution. Changing the conditions under which the SF fiber dissolved in the Lithium Boride (LiBr) solution resulted in altering the MW distribution of SF solution. Under optimal salting-out conditions (ionic strength > 0.7 M and pH > 7) and using a smaller and narrower SF MW distribution, SF microspheres with smoother shapes and more uniform sizes were produced. Meanwhile, the size and polydispersity of the microspheres increased when the SF concentration was increased from 0.25 mg/mL to 20 mg/mL. The improved SF microspheres, obtained by altering the distribution of molecular weight, have potential in drug and gene delivery applications. - Highlights: • MW distribution was changed by applying different dissolving methods of SF fiber. • Smaller and narrower MW distribution improves the quality of SF microspheres. • Size and polydispersity of microspheres increase as SF concentration increases. • Improved SF microspheres have potential in drug and gene delivery applications.

  19. Self-esteem and quality of life in adolescents with extreme obesity in Saudi Arabia: the effect of weight loss after laparoscopic sleeve gastrectomy.

    Science.gov (United States)

    Aldaqal, Saleh M; Sehlo, Mohammad G

    2013-01-01

    To evaluate the self-esteem and quality of life in adolescents with extreme obesity before and one year after laparoscopic sleeve gastrectomy as obesity is a major challenging medical problem, not only in adults but also in children and adolescents in Saudi Arabia. In a prospective cohort study, 32 adolescents (aged 13-17 years) with extreme obesity (Group 1) presenting for laparoscopic sleeve gastrectomy (LSG) were compared with 32 matched, healthy, nonobese adolescents (aged 14-17 years) (Group 2) with regards to self-esteem and quality of life. Assessment was done using the Rosenberg Self-Esteem Scale and Pediatric Quality of Life Inventory version 4.0 (self- and parent report), respectively. Body mass index (BMI) Z scores were calculated for both groups. We found significantly poor self-esteem and impairment in all domains of quality of life (self- and parent report) in Group 1 compared with Group 2 (PSelf esteem and quality of life (self- and parent reports) significantly improved 1 year after LSG (Pself-esteem (R2=0.28 and P=.003) and quality of life (R(2)=0.67 and Padolescents with extreme obesity: LSG leads to weight loss, with subsequent improvement in self-esteem and quality of life. Copyright © 2013 Elsevier Inc. All rights reserved.

  20. Automatic weight determination in nonlinear model predictive control of wind turbines using swarm optimization technique

    Science.gov (United States)

    Tofighi, Elham; Mahdizadeh, Amin

    2016-09-01

    This paper addresses the problem of automatic tuning of weighting coefficients for the nonlinear model predictive control (NMPC) of wind turbines. The choice of weighting coefficients in NMPC is critical due to their explicit impact on efficiency of the wind turbine control. Classically, these weights are selected based on intuitive understanding of the system dynamics and control objectives. The empirical methods, however, may not yield optimal solutions especially when the number of parameters to be tuned and the nonlinearity of the system increase. In this paper, the problem of determining weighting coefficients for the cost function of the NMPC controller is formulated as a two-level optimization process in which the upper- level PSO-based optimization computes the weighting coefficients for the lower-level NMPC controller which generates control signals for the wind turbine. The proposed method is implemented to tune the weighting coefficients of a NMPC controller which drives the NREL 5-MW wind turbine. The results are compared with similar simulations for a manually tuned NMPC controller. Comparison verify the improved performance of the controller for weights computed with the PSO-based technique.

  1. C-Reactive Protein and Procalcitonin Diagnostic Value in Congenital Infection in Newborns with Extremely Low and Very Low Birth Weight

    Directory of Open Access Journals (Sweden)

    O. V. Mikhaylova

    2015-01-01

    Full Text Available The high frequency of infectious complications in the early neonatal period of adaptation in infants with extremely low (ELBW and very low birth weight (VLBW attracts particular attention. The aim of our study was to evaluate the sensitivity (Se and specificity (Sp of C-reactive protein and procalcitonin in congenital pneumonia and congenital sepsis in newborn infants with extremely low and very low birth weight.Methods. In 160 preterm newborns that were included in our prospective study, 33 had early neonatal sepsis, 42 children had congenital pneumonia, and 85 infants were without neonatal infection. A comprehensive clinical and laboratoryinstrumental examination of the newborn was done, including determining the concentration of C-reactive protein and procalcitonin at the age of 48–72 hours of life. Results. Low sensitivity of CRP at the age of 48–72 hours of life in congenital sepsis and congenital pneumonia was observed. However, under these pathological conditions CRP and PCT are characterized by high specificity. It should also be noted that PCT has a high sensitivity in children with congenital sepsis aged 48–72 hours. Moreover, PCT also has a high specificity (Sp 80,6%, which determines its advantage in the use of sepsis diagnosis in extremely premature infants compared to CRP.Conclusion. Maximum specificity reaches 100%, co-located with the assessment of CRP and PCT, which determines the feasibility of using this combination for verification of congenital infectious conditions such as sepsis and pneumonia in children ELBW and VLBW aged 48–72 hours.

  2. Daily Self-Weighing to Control Body Weight in Adults: A Critical Review of the Literature.

    Science.gov (United States)

    Pacanowski, Carly R; Bertz, Fredrik C; Levitsky, David A

    2014-01-01

    The objective of this study is to review the history of daily self-weighing for weight control, discuss the possibility that self-weighing may cause adverse psychological symptoms, and propose mechanisms that explain how self-weighing facilitates weight control. A systematic forward (citation) tracking approach has been employed in this study. In the early literature, experimental tests did not demonstrate a benefit of adding daily self-weighing to traditional behavioral modification for weight loss. More recent studies have shown that daily self-weighing combined with personalized electronic feedback can produce and sustain weight loss with and without a traditional weight loss program. Daily self-weighing appears to be effective in preventing age-related weight gain. Apart from these experimental findings, there is considerable agreement that the frequency of self-weighing correlates with success in losing weight and sustaining the weight loss. The early literature suggested frequent self-weighing may be associated with negative psychological effects. However, more recent experimental trials do not substantiate such a causal relationship. In conclusion, daily self-weighing may be a useful strategy for certain adults to prevent weight gain, lose weight, or prevent weight regain after loss. More research is needed to better understand the role of different types of feedback, who benefits most from self-weighing, and at what frequency.

  3. Turbulent Extreme Event Simulations for Lidar-Assisted Wind Turbine Control

    Science.gov (United States)

    Schlipf, David; Raach, Steffen

    2016-09-01

    This work presents a wind field generator which allows to shape wind fields in the time domain while maintaining the spectral properties. This is done by an iterative generation of wind fields and by minimizing the error between wind characteristics of the generated wind fields and desired values. The method leads towards realistic ultimate load calculations for lidar-assisted control. This is demonstrated by fitting a turbulent wind field to an Extreme Operating Gust. The wind field is then used to compare a baseline feedback controller alone against a combined feedback and feedforward controller using simulated lidar measurements. The comparison confirms that the lidar-assisted controller is still able to significantly reduce the ultimate loads on the tower base under this more realistic conditions.

  4. [The use of caspofungin in extremely low birth weight preterm infants based on clinical trials and reports considering the own experience (case report)].

    Science.gov (United States)

    Stempniewicz, Krzysztof; Walas, Wojciech; Gregorek-Pełka, Edyta; Kamińska, Ewa

    2014-01-01

    In recent years, despite of significant progress in the treatment of premature infants with extremely low body weight, still a significant problem remains severe, treatment-resistant generalized infections among which the percentage of fungal infections is increasing. The invasive candidiasis, especially caused by non-albicans species of Candida, are of particular importance. In the case of resistance on fluconazole and amphotericin B the use of echinocandin drug may be a useful choice. This paper reviews the pharmacokinetics of caspofungin in neonates and children, as well as the case reports and clinical trials on the use of caspofungin in neonates, including the premature infants. We describe also the premature neonate with low birth weight and a generalized infection caused by Candida glabrata, where, despite of the treatment based on the sensitivity of the fungus it did not achieve clinical improvement and sterilization of cultures. It was not until the lead-in of caspofungin in dose 2 mg/kg/day allowed to cure the patient. There was a transient increase in the activity of aminotransferases and level of bilirubin as a complication of treatment. At the end of application of caspofungin the liver functions have been slowly normalized. Caspofungin appeared to be effective in the treatment of systemic fungal C. glabrata in premature neonate with extremely low birth weight. Echinocandins, including caspofungin, appear to be a promising alternative to previously used agents in the treatment of invasive Candida infections in newborns. However, the further randomized trials on the use of caspofungin in preterm neonates, regarding long term follow-up, should be undertaken.

  5. Virtual reality for upper extremity rehabilitation in early stroke: a pilot randomized controlled trial.

    Science.gov (United States)

    Yin, Chan Wai; Sien, Ng Yee; Ying, Low Ai; Chung, Stephanie Fook-Chong Man; Tan May Leng, Dawn

    2014-11-01

    To investigate the effect of virtual reality (VR) rehabilitation on upper extremity motor performance of patients with early stroke. Pilot randomized controlled trial. Rehabilitation wards. Twenty three adults with stroke (mean age (SD) = 58.35 (13.45) years and mean time since stroke (SD) = 16.30 (7.44) days). Participants were randomly assigned to VR group (n=11) or control group (n=12). VR group received nine 30 minutes upper extremity VR therapy in standing (five weekdays in two weeks) plus conventional therapy, which included physical and occupational therapy. Control group received only conventional therapy, which was comparable to total training time received by VR group (mean training hours (SD):VR = 17.07 (2.86); control = 15.50 (2.79)). The main outcome measure was the Fugl-Meyer Assessment (FMA). Secondary outcomes included Action Research Arm Test, Motor Activity Log and Functional Independence Measure. Results were taken at baseline, post intervention and 1-month post intervention. Participants' feedback and adverse effects were recorded. All participants improved in FMA scores (mean change (SD) = 11.65 (8.56), Ptherapy alone, this study demonstrates the feasibility of VR training in early stroke. © The Author(s) 2014.

  6. A Review of Weight Control Strategies and Their Effects on the Regulation of Hormonal Balance

    Directory of Open Access Journals (Sweden)

    Neil A. Schwarz

    2011-01-01

    Full Text Available The estimated prevalence of obesity in the USA is 72.5 million adults with costs attributed to obesity more than 147 billion dollars per year. Though caloric restriction has been used extensively in weight control studies, short-term success has been difficult to achieve, with long-term success of weight control being even more elusive. Therefore, novel approaches are needed to control the rates of obesity that are occurring globally. The purpose of this paper is to provide a synopsis of how exercise, sleep, psychological stress, and meal frequency and composition affect levels of ghrelin, cortisol, insulin GLP-1, and leptin and weight control. We will provide information regarding how hormones respond to various lifestyle factors which may affect appetite control, hunger, satiety, and weight control.

  7. fMRI of Simultaneous Interpretation Reveals the Neural Basis of Extreme Language Control.

    Science.gov (United States)

    Hervais-Adelman, Alexis; Moser-Mercer, Barbara; Michel, Christoph M; Golestani, Narly

    2015-12-01

    We used functional magnetic resonance imaging (fMRI) to examine the neural basis of extreme multilingual language control in a group of 50 multilingual participants. Comparing brain responses arising during simultaneous interpretation (SI) with those arising during simultaneous repetition revealed activation of regions known to be involved in speech perception and production, alongside a network incorporating the caudate nucleus that is known to be implicated in domain-general cognitive control. The similarity between the networks underlying bilingual language control and general executive control supports the notion that the frequently reported bilingual advantage on executive tasks stems from the day-to-day demands of language control in the multilingual brain. We examined neural correlates of the management of simultaneity by correlating brain activity during interpretation with the duration of simultaneous speaking and hearing. This analysis showed significant modulation of the putamen by the duration of simultaneity. Our findings suggest that, during SI, the caudate nucleus is implicated in the overarching selection and control of the lexico-semantic system, while the putamen is implicated in ongoing control of language output. These findings provide the first clear dissociation of specific dorsal striatum structures in polyglot language control, roles that are consistent with previously described involvement of these regions in nonlinguistic executive control.

  8. Pharmacoeconomic impact of use of the probiotic Lactobacillus reuteri DSM 17938 for prevention of necrotizing enterocolitis in extremely low-birth-weight infants

    Directory of Open Access Journals (Sweden)

    Dimaguila MAVT

    2013-04-01

    Full Text Available Mary Ann VT Dimaguila,1,2 Peter Gal,1,3,4 Tiffany Wilson,1 John E Wimmer Jr,1,2 McCrae Smith,1,2 Rita Q Carlos,1,2 Christie C Davanzo,1,2 J Laurence Ransom1,2 1Women's Hospital of Greensboro, Cone Health, Greensboro, NC, USA; 2Piedmont Neonatology, Greensboro, NC, USA; 3Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA; 4Greensboro Area Health Education Center, Greensboro, NC, USA Background: A recent study showed that use of Lactobacillus reuteri as probiotic prophylaxis decreased the necrotizing enterocolitis (NEC rate from 15.1% to 2.5% in neonates with birth weight below 1000 g. Given the controversies surrounding use of probiotics in neonatal intensive care units, we address one additional aspect of routine implementation of probiotics for NEC prophylaxis – the pharmacoeconomic impact. Methods: Using data from our initial published experience, and continuing data collection after instituting a higher dose of L. reuteri, we measured the reduction in NEC in neonates with birth weight below 1000 g. Cost savings from prior studies examining the cost and outcomes of medical and surgical NEC were used to calculate the financial impact of routine L. reuteri DSM 17938 prophylaxis. Results: Medical records for 354 neonates were reviewed, 232 in the years before introduction of L. reuteri prophylaxis and 79 who received L. reuteri prophylaxis dosed at 0.1 mL daily and 43 neonates given a total daily dose of 0.2 mL as one or two doses. The incidence of NEC was significantly lower in the neonates who received L. reuteri (two of 122 neonates [1.6%] versus 35 of 232 neonates [15.1%]. The expected benefits for our neonatal intensive care unit per 100 extremely low-birth-weight neonates treated were four fewer deaths, five fewer cases of medical NEC, eight fewer cases of surgical NEC, one less patient with short-bowel syndrome, and a cost saving of approximately $2.2 million. Conclusion: Prophylactic

  9. Web-based Weight Loss in Primary Care: A Randomized Controlled Trial

    OpenAIRE

    Bennett, Gary G.; Herring, Sharon J.; Puleo, Elaine; Stein, Evelyn K.; Emmons, Karen M; Gillman, Matthew W.

    2009-01-01

    Evidence is lacking regarding effective and sustainable weight loss approaches for use in the primary care setting. We conducted a 12-week randomized controlled trial to evaluate the short-term efficacy of a web-based weight loss intervention among 101 primary care patients with obesity and hypertension. Patients had access to a comprehensive website that used a moderate-intensity weight loss approach designed specifically for web-based implementation. Patients also participated in four (two ...

  10. On the equilibrium of a extremely extended and diluted magneto-matter state subject to its weight.

    Science.gov (United States)

    Berdichevsky, Daniel

    Solutions to the force relationship between the magnetic stresses and the self-gravitational force are discussed for a simple homogeneous distribution of matter coalescent to a magnetic field in a cylindrical geometry. Consideration are given to the needed permeability of the medium to make it capable of supporting many times the mass of the Sun, on an extension of several parsecs to kiloparsec. This state of self organization of matter and magnetic field (magneto-matter state) has proven useful interpretation for the explanation of anomalous thermodynamic of the gas of electrons contained in flux-tubes with a twist, low-beta, often observed at 1 AU in the interplanetary medium, Berdichevsky and Shefers, 2015. This state of matter, which most basic property, the freezing in the magnetic field, see e.g., Chew et al, 1956, has proved to exist in the regions where robotic observations in the near and far space perform detailed observations of magnetic fields, and extreme dilute plasma (commonly about 1000 to 0.1 or less ionized particles per cubic cm). This work is in many ways an extension of Alfven work on magnetized space plasmas, Alven, 1942. Berdichevsky, D.B., and K., Schefers, ApJ, 803, 70, 2015, doi: 10.1088/0004-637X/805/1/70 Chew, G.F., M.L., Goldberger, and F.E. Low, 1956, the Royal Soc. London, section Math & Phys Sc., 236, pp. 112. Alfv'e n, H (1942). ``Existence of electromagnetic-hydrodynamic waves.'' Nature 150, 405 doi:10.1038/150405d0

  11. Developing a consumer evaluation tool of weight control strategy advertisements on the Internet.

    Science.gov (United States)

    Luevorasirikul, Kanokrat; Gray, Nicola J; Anderson, Claire W

    2008-06-01

    To develop two evaluation tools for weight loss and weight gain advertisements on the Internet in order to help consumers to evaluate the quality of information within these advertisements. One hundred websites identified by Internet search engines for weight loss and weight gain strategies (50 websites each) were evaluated using two specific scoring instruments, developed by adapting questions from the 'DISCERN' tool and reviewing all related weight control guidelines and advertising regulations. The validity and reliability of the adapted tools were tested. Our evaluation tools rated the information from most websites as poor quality (70%). In the case of weight loss strategies, statements about rapid (18%) and permanent (28%) weight loss caused concern as well as lack of sensible advice about dieting and a lack of product warnings (84%). Safety concerns relating to weight gain products were the lack of warnings about side effects in products containing steroids and creatine (92%). The adapted tools exhibited acceptable validity and reliability. Quality of information within weight control advertisements on the Internet was generally poor. Problems of false claims, little advice on healthy ways to modify weight and few warnings on side effects have been highlighted in this study.

  12. Adaptive Control of a Wearable Exoskeleton for Upper-Extremity Neurorehabilitation

    Directory of Open Access Journals (Sweden)

    Sivakumar Balasubramanian

    2012-01-01

    Full Text Available The paper describes the implementation and testing of two adaptive controllers developed for a wearable, underactuated upper extremity therapy robot – RUPERT (Robotic Upper Extremity Repetitive Trainer. The controllers developed in this study were used to implement two adaptive robotic therapy modes – the adaptive co-operative mode and the adaptive active-assist mode – that are based on two different approaches for providing robotic assistance for task practice. The adaptive active-assist mode completes therapy tasks when a subject is unable to do so voluntarily. This robotic therapy mode is a novel implementation of the idea of an active-assist therapy mode; it utilizes the measure of a subject’s motor ability, along with their real-time movement kinematics to initiate robotic assistance at the appropriate time during a movement trial. The adaptive co-operative mode, on the other hand, is based on the idea of enabling task completion instead of completing the task for the subject. Both these therapy modes were designed to adapt to a stroke subject's motor ability, and thus encourage voluntary participation from the stroke subject. The two controllers were tested on three stroke subjects practicing robot-assisted reaching movements. The results from this testing demonstrate that an underactuated wearable exoskeleton, such as RUPERT, can be used for administering robot-assisted therapy, in a manner that encourages voluntary participation from the subject undergoing therapy.

  13. Scientific Opinion on the essential composition of total diet replacements for weight control

    DEFF Research Database (Denmark)

    Tetens, Inge

    to induce a substantial energy deficit in overweight or obese adults who wish to lose weight and replace the whole diet in the context of energy-restricted diets for weight reduction. In this opinion, the Panel proposed a minimum protein content based on a Population Reference Intake for protein adjusted......Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) was asked to deliver a scientific opinion on the essential composition of total diet replacements for weight control. Total diet replacements for weight control are intended...... or authoritative bodies. Derived from the minimum content of macronutrients, the Panel proposed a minimum energy content of total diet replacements for weight control of 2 510 kJ/day (600 kcal/day). The Panel also advised on potential conditions and restrictions of use for these products....

  14. Crescimento de prematuros de extremo baixo peso nos primeiros dois anos de vida Growth of extremely low birth weight infants during the first two years of life

    Directory of Open Access Journals (Sweden)

    Ligia Maria S. S. Rugolo

    2007-06-01

    Full Text Available OBJETIVO: Analisar o padrão de crescimento de prematuros de extremo baixo peso (EBP até 24 meses de idade corrigida, a influência da displasia broncopulmonar (DBP e os fatores de risco para falha de crescimento. MÉTODOS: Coorte de prematuros OBJECTIVE: To evaluate the growth pattern of extremely low birth weight infants(ELBW from birth to 24 months of adjusted gestational age (AA, the influence of bronchopulmonary dysplasia (BPD and risk factors associated to growth failure. METHODS: This cohort study included all singleton inborn infants with birthweight <1,000g, admitted in the follow-up clinic of a level III Perinatal Center. Weight, length and head circumference were measured at birth, 40 weeks, and 3, 6, 9, 12, 18, 24 months AA, and Z-scores were calculated. Out of the 82 survivors, 70 were studied and classified in two groups: BPD (n=41 and no-BPD (n=29. Statistical analysis included t-test or Mann-Withney, chi-square or Fisher Exact test, and multivariate logistic regression. RESULTS: In both groups, weight z-score decreased significantly between birth and 40 weeks AA. A peak incremental change in weight, length and head circumference z-scores occurred between 40 weeks and three months. Z-scores for the no-BPD group were close to the expected values by the age of six months and remained at these levels at 24 months AA. Children with BPD had lower z-scores for weight and head circumference in the first year of life, but no difference was found between BPD and no-BPD children in the second year of life. Regression analysis showed that catch-down in weight z-score at 40 weeks was a risk factor for failure to thrive. CONCLUSIONS: ELBW infants experienced early catch-up growth during the first two years of life. ELBW with BPD had poor weight gain. Post-natal growth restriction predicts failure to thrive in infancy.

  15. Self-weighing and weight control behaviors among adolescents with a history of overweight.

    Science.gov (United States)

    Alm, Mary E; Neumark-Sztainer, Dianne; Story, Mary; Boutelle, Kerri N

    2009-05-01

    To assess the relationships between self-weighing frequency, weight control behaviors, and weight status among male and female adolescents who have a history of being overweight. This study compared weight control behaviors between two groups of adolescents with a history of being overweight (body mass index [BMI] >85th percentile): those who weighed themselves weekly or more (frequent self-weighers) and those who weighed themselves monthly or less (infrequent self-weighers). Participants completed a survey on weight control behaviors, dietary intake, physical activity, and sedentary activity. Height and weight were also measured. Logistic regression analyses were used for categorical outcomes and linear regressions for continuous outcomes. Of the 130 adolescents, 43% were frequent weighers and 57% were infrequent weighers. In comparison to infrequent self-weighers, frequent self-weighers were more likely to report using behavior change strategies, following a structured diet, and engaging in healthy weight control behaviors, especially decreasing caloric intake, high fat food intake, and "junk food" intake. Also, more frequent self-weighers reported engaging in more strenuous physical activity and spending less time playing videogames than infrequent self-weighers. Although not significant, a trend resulted indicating lower average BMI percentile among frequent self-weighers. No significant differences were found between the two groups in unhealthy weight control behaviors. These results suggest that adolescents with a history of overweight who self-weigh at least weekly are more likely to report using healthy weight control behaviors than adolescents who self-weigh monthly or less frequently. Self-monitoring of weight may be a useful component of a comprehensive weight management plan for some overweight adolescents.

  16. Tomographic control for wide field AO systems on extremely large telescopes

    Science.gov (United States)

    Petit, C.; Conan, J.-M.; Fusco, T.; Neichel, B.

    2010-07-01

    We investigate in this article tomographic control using both Laser and Natural Guide Stars (LGS and NGS) in the particular framework of the European Extremely Large Telescope (E-ELT) Wide Field Adaptive Optics (WFAO) modules design. A similar global control strategy has been indeed derived for both the Laser Tomographic Adaptive Optics (LTAO) and Multi-Conjugate Adaptive Optics (MCAO) modules of the E-ELT, due to similar constraints. This control strategy leads in both cases to a split control of low order modes measured thanks to NGS and high order modes measured thanks to LGS. We investigate here this split tomographic control, compared to an optimal coupled solution. To support our analysis, a dedicated simulation code has been developed. Indeed, due to the huge complexity of the EELT, fast simulation tools must be considered to explore quickly the tomographic issues. We describe our control strategy which has lead to considering split tomographic control. First results on Tomography for E-ELT WFAO systems are then presented and discussed.

  17. Associations between body weight perception and weight control behaviour in South Indian children: a cross-sectional study

    OpenAIRE

    Swaminathan, Sumathi; Selvam, Sumithra; Pauline, Maria; Vaz, Mario

    2013-01-01

    Objective To examine the patterns of weight loss behaviour and the association between weight loss attempts with actual weight status and children's and parental perceptions of weight status. Design A cross-sectional study. Setting Karnataka, South India. Participants 1874 girls and boys aged 8–14 years from seven schools in Karnataka, South India. Main outcome measures The association between weight loss attempts and sociodemographic factors, weight status and the child's or the parent's per...

  18. Use and Cutaneous Side Effects of Skin Antiseptics in Extremely Low Birth Weight Infants - A Retrospective Survey of the German NICUs.

    Science.gov (United States)

    Biermann, C D; Kribs, A; Roth, B; Tantcheva-Poor, I

    2016-07-01

    Background Nosocomial infections are a serious problem in the treatment of extremely low birth weight infants (ELBW, Octenidine without phenoxyethanol (OwPh) and Octenisept(®) were the predominantly used skin antiseptics for intensive-care procedures. At least one skin complication was reported by 27% (n=17) of the NICUs. In 9 cases Octenisept(®) was used, and in 6 cases octenidine was used. According to our knowledge, this is the first study surveying practices and safety of skin antisepsis in ELBWs in the German NICUs. Most German NICUs use octenidine, however, in different preparations. Skin complications including blistering, necrosis and scarring were seen with all octenidine products, a fact which has not been previously reported. © Georg Thieme Verlag KG Stuttgart · New York.

  19. Reduced Hospital Mortality With Surgical Ligation of Patent Ductus Arteriosus in Premature, Extremely Low Birth Weight Infants: A Propensity Score-matched Outcome Study.

    Science.gov (United States)

    Tashiro, Jun; Perez, Eduardo A; Sola, Juan E

    2016-03-01

    To evaluate outcomes after surgical ligation (SL) of patent ductus arteriosus (PDA) in premature, extremely low birth weight (ELBW) infants. Optimal management of PDA in this specialized population remains undefined. Currently, surgical therapy is largely reserved for infants failing medical management. To date, a large-scale, risk-matched population-based study has not been performed to evaluate differences in mortality and resource utilization. Data on identified premature (Propensity score-matched analysis of 1620 SL versus 1584 non-SL found reduced mortality (15% vs 26%) and more routine disposition (48% vs 41%) for SL (P Propensity score-matched analysis demonstrates reduced mortality in premature/ELBW infants with SL for PDA. NEC and sepsis are predictors of mortality and resource utilization.

  20. Common endocrine control of body weight, reproduction, and bone mass

    Science.gov (United States)

    Takeda, Shu; Elefteriou, Florent; Karsenty, Gerard

    2003-01-01

    Bone mass is maintained constant between puberty and menopause by the balance between osteoblast and osteoclast activity. The existence of a hormonal control of osteoblast activity has been speculated for years by analogy to osteoclast biology. Through the search for such humoral signal(s) regulating bone formation, leptin has been identified as a strong inhibitor of bone formation. Furthermore, intracerebroventricular infusion of leptin has shown that the effect of this adipocyte-derived hormone on bone is mediated via a brain relay. Subsequent studies have led to the identification of hypothalamic groups of neurons involved in leptin's antiosteogenic function. In addition, those neurons or neuronal pathways are distinct from neurons responsible for the regulation of energy metabolism. Finally, the peripheral mediator of leptin's antiosteogenic function has been identified as the sympathetic nervous system. Sympathomimetics administered to mice decreased bone formation and bone mass. Conversely, beta-blockers increased bone formation and bone mass and blunted the bone loss induced by ovariectomy.

  1. DTIPrep: Quality Control of Diffusion-Weighted Images

    Directory of Open Access Journals (Sweden)

    Ipek eOguz

    2014-01-01

    Full Text Available In the last decade, diffusion MRI (dMRI studies of the human and animal brain have been used to investigate a multitude of pathologies and drug-related effects in neuroscience research. Study after study identifies white matter (WM degeneration as a crucial biomarker for all these diseases. The tool of choice for studying WM is dMRI. However, dMRI has inherently low signal-to-noise ratio and its acquisition requires a relatively long scan time; in fact, the high loads required occasionally stress scanner hardware past the point of physical failure. As a result, many types of artifacts implicate the quality of diffusion imagery. Using these complex scans containing artifacts without quality control (QC can result in considerable error and bias in the subsequent analysis, negatively affecting the results of research studies using them. However, dMRI QC remains an under-recognized issue in the dMRI community as there are no user-friendly tools commonly available to comprehensively address the issue of dMRI QC. As a result, current dMRI studies often perform a poor job at dMRI QC.Thorough QC of diffusion MRI will reduce measurement noise and improve reproducibility, and sensitivity in neuroimaging studies; this will allow researchers to more fully exploit the power of the dMRI technique and will ultimately advance neuroscience. Therefore, in this manuscript, we present our open-source software, DTIPrep, as a unified, user friendly platform for thorough quality control of dMRI data. These include artifacts caused by eddy-currents, head motion, bed vibration and pulsation, venetian blind artifacts, as well as slice-wise and gradient-wise intensity inconsistencies. This paper summarizes a basic set of features of DTIPrep described earlier and focuses on newly added capabilities related to directional artifacts and bias analysis.

  2. Influence of the control system on wind turbine loads during power production in extreme turbulence: Structural reliability

    DEFF Research Database (Denmark)

    Abdallah, Imad; Natarajan, Anand; Sørensen, John Dalsgaard

    2016-01-01

    The wind energy industry is continuously researching better computational models of wind inflow and turbulence to predict extreme loading (the nature of randomness) and their corresponding probability of occurrence. Sophisticated load alleviation control systems are increasingly being designed an...

  3. Obesity, Body Image, Depression, and Weight-control Behaviour Among Female University Students in Korea

    National Research Council Canada - National Science Library

    Jun, Eun Mi; Choi, Seung Bae

    2014-01-01

    .... The purpose of the study was to examine obesity, body image, depression, and weight-control behaviour among Korean female university students and investigate the differences in body image, depression...

  4. Commercial weight loss diets meet nutrient requirements in free living adults over 8 weeks: A randomised controlled weight loss trial

    Directory of Open Access Journals (Sweden)

    Macdonald Ian

    2008-09-01

    Full Text Available Abstract Objective To investigate the effect of commercial weight loss programmes on macronutrient composition and micronutrient adequacy over a 2 month period. Design Adults were randomly allocated to follow the Slim Fast Plan, Weight Watchers Pure Points Programme, Dr Atkins' New Diet Revolution, or Rosemary Conley's "Eat Yourself Slim" Diet & Fitness Plan. Setting A multi-centre randomised controlled trial. Subjects 293 adults, mean age 40.3 years and a mean BMI 31.7 (range 27–38 were allocated to follow one of the four diets or control group. Subjects completed a 7-day food and activity diary at baseline (prior to randomisation and after 2 months. Diet records were analysed for nutrient composition using WinDiets (research version. Results A significant shift in the macronutrient composition of the diet with concurrent alteration of the micronutrient profile was apparent with all diets. There was no evidence to suggest micronutrient deficiency in subjects on any of the dietary regimens. However, those sub-groups with higher needs for specific micronutrients, such as folate, iron or calcium may benefit from tailored dietary advice. Conclusion The diets tested all resulted in considerable macronutrient change and resulted in an energy deficit indicating dietary compliance. Health professionals and those working in community and public health should be reassured of the nutritional adequacy of the diets tested. Trial Registration Number NCT00327821

  5. Obesity, Body Image, Depression, and Weight-control Behaviour Among Female University Students in Korea

    OpenAIRE

    Jun, Eun Mi; Choi, Seung Bae

    2014-01-01

    Background: Obesity has become epidemic worldwide and 31.0% of Korean adults are obese. Obesity is the main cause of chronic diseases, such as diabetes, hypertension, cardiac disease, and cancer. The purpose of the study was to examine obesity, body image, depression, and weight-control behaviour among Korean female university students and investigate the differences in body image, depression, and weight-control behaviour with respect to obesity. Methods: This study examined obesity, body ima...

  6. Quantifying feedforward control: a linear scaling model for fingertip forces and object weight

    Science.gov (United States)

    Lu, Ying; Bilaloglu, Seda; Aluru, Viswanath

    2015-01-01

    The ability to predict the optimal fingertip forces according to object properties before the object is lifted is known as feedforward control, and it is thought to occur due to the formation of internal representations of the object's properties. The control of fingertip forces to objects of different weights has been studied extensively by using a custom-made grip device instrumented with force sensors. Feedforward control is measured by the rate of change of the vertical (load) force before the object is lifted. However, the precise relationship between the rate of change of load force and object weight and how it varies across healthy individuals in a population is not clearly understood. Using sets of 10 different weights, we have shown that there is a log-linear relationship between the fingertip load force rates and weight among neurologically intact individuals. We found that after one practice lift, as the weight increased, the peak load force rate (PLFR) increased by a fixed percentage, and this proportionality was common among the healthy subjects. However, at any given weight, the level of PLFR varied across individuals and was related to the efficiency of the muscles involved in lifting the object, in this case the wrist and finger extensor muscles. These results quantify feedforward control during grasp and lift among healthy individuals and provide new benchmarks to interpret data from neurologically impaired populations as well as a means to assess the effect of interventions on restoration of feedforward control and its relationship to muscular control. PMID:25878151

  7. Links between motor control and classroom behaviors: Moderation by low birth weight.

    Science.gov (United States)

    Razza, Rachel A; Martin, Anne; Brooks-Gunn, Jeanne

    2016-08-01

    It is unclear from past research on effortful control whether one of its components, motor control, independently contributes to adaptive classroom behaviors. The goal of this study was to identify associations between early motor control, measured by the walk-a-line task at age 3, and teacher-reported learning-related behaviors (approaches to learning and attention problems) and behavior problems in kindergarten classrooms. Models tested whether children who were vulnerable to poorer learning behaviors and more behavior problems due to having been born low birth weight benefited more, less, or the same as other children from better motor control. Data were drawn from the national Fragile Families and Child-Wellbeing Study (n = 751). Regression models indicated that motor control was significantly associated with better approaches to learning and fewer behavior problems. Children who were low birth weight benefitted more than normal birth weight children from better motor control with respect to their approaches to learning, but equally with respect to behavior problems. Additionally, for low but not normal birth weight children, better motor control predicted fewer attention problems. These findings suggest that motor control follows a compensatory model of development for low birth weight children and classroom behaviors.

  8. PI control based on fuzzy set-point weighting tracking for hydraulic crane boom system

    Institute of Scientific and Technical Information of China (English)

    Yong YANG; An LUO; Karl-Erik RYDBERG

    2006-01-01

    A PI control strategy based on fuzzy set-point weighting following was proposed for the active damping control of a hydraulic crane boom system (HCBS). Two valve-controlled PI controllers, which include a proportional feedforward controller based on fuzzy set-point weighting following and a limited semi-integrator(LSI), are designed respectively. LSI is used to limit output signal and to prevent wind up at the low frequency of the spectrum. By using a range camera and an electronic feedback control, the tip damping on the HCBS can be adjusted artificially. A collaborative control simulation technique of HOPSAN and MATLAB/SIMULINK is applied to the controller design. Simulation results show that the proposed PI control system has less overshoot as well as faster response. The tip damping on the HCBS during operation is improved.

  9. The effect of weight controllability beliefs on prejudice and self-efficacy.

    Science.gov (United States)

    Thorsteinsson, Einar B; Loi, Natasha M; Breadsell, Dana

    2016-01-01

    An experiment was conducted to test for the presence of prejudice towards obesity and whether weight controllability beliefs information reduces this prejudice and impacts on a person's own healthy eating self-efficacy. The experiment randomly allocated 346 participants (49 males) into one of three conditions: controllable contributors toward obesity condition (e.g., information about personal control about diet and exercise); uncontrollable contributors toward obesity condition (e.g., information about genes, factors in society); and a control condition with no information given. Prejudice was present in 81% of the sample. High prejudice was predicted by low self-efficacy for exercise and weight. Weight controllability beliefs information had no significant effect on prejudice levels or exercise or healthy eating self-efficacy levels. Future research directions are discussed.

  10. Binder extraction from green multilayer ceramics using a weight loss rate-controlled thermogravimetric analyzer

    Science.gov (United States)

    Witt, Jason; Speyer, Robert F.; Murali, Lakshman

    1997-06-01

    A weight loss rate-controlled organic extraction furnace was built and demonstrated using a multilayer green ceramic. Multirate weight loss schedules as well as automated atmosphere control and detection were demonstrated. The low thermal mass furnace showed good tracking with 300 °C heating and cooling rates. This furnace, coupled with appropriate PID control constants, facilitated feedback control which could extract organics rapidly without self-ignition to uncontrolled combustion. Controlled organic burnout was demonstrated at weight loss rates up to 0.5%/min in air. Damage-free multilayers were observed using a burnout rate requiring 150 min for extraction, rather than the days commonly associated with this task when using conventional furnaces.

  11. Dietary fats, teas, dairy, and nuts: potential functional foods for weight control?

    Science.gov (United States)

    St-Onge, Marie-Pierre

    2005-01-01

    Functional foods are similar to conventional foods in appearance, but they have benefits that extend beyond their basic nutritional properties. For example, functional foods have been studied for the prevention of osteoporosis, cancer, and cardiovascular disease. They have yet to be related to the prevention of obesity, although obesity is one of the major health problems today. The inclusion of foods or the replacement of habitual foods with others that may enhance energy expenditure (EE) or improve satiety may be a practical way to maintain a stable body weight or assist in achieving weight loss; such foods may act as functional foods in body weight control. Some foods that might be classified as functional foods for weight control because of their effects on EE and appetite-including medium-chain triacylglycerols, diacylglycerols, tea, milk, and nuts-are reviewed here. Only human studies reporting EE, appetite, or body weight are discussed. When studies of whole food items are unavailable, studies of nutraceuticals, the capsular equivalents of functional foods, are reviewed. To date, dietary fats seem to be most promising and have been the most extensively studied for their effects on body weight control. However, the weight loss observed is small and should be considered mostly as a measure to prevent weight gain. Carefully conducted clinical studies are needed to firmly ascertain the effect of tea, milk, and nuts on body weight maintenance, to assess their potential to assist in weight-loss efforts, and to ascertain dose-response relations and mechanisms of action for the 4 food types examined.

  12. Weight control behaviors in overweight/obese U.S. adults with diagnosed hypertension and diabetes

    Directory of Open Access Journals (Sweden)

    Li Chaoyang

    2009-03-01

    Full Text Available Abstract Background Obesity is a major risk factor for development and progression of hypertension and diabetes, which often coexist in obese patients. Losing weight by means of energy restriction and physical activity has been effective in preventing and managing these diseases. However, weight control behaviors among overweight/obese adults with these conditions are poorly understood. Methods Using self-reported data from 143,386 overweight/obese participants (aged ≥ 18 years in the 2003 Behavioral Risk Factor Surveillance System, we examined the proportion of overweight/obese adults who tried to lose weight and their weight control strategies by hypertension and/or diabetes status. Results Among all participants, 58% of those with hypertension, 60% of those with diabetes, and 72% of those with both diseases tried to lose weight, significantly higher than the 50% of those with neither condition (Bonferroni corrected P Conclusion The proportion of overweight/obese patients with diagnosed hypertension and/or diabetes who attempted to lose weight remains suboptimal and the weight control strategies varied significantly among these patients.

  13. Asthma and obesity: does weight loss improve asthma control? a systematic review

    Directory of Open Access Journals (Sweden)

    Juel CTB

    2012-06-01

    Full Text Available Caroline Trunk-Black Juel,1 Zarqa Ali,1 Lisbeth Nilas,2 Charlotte Suppli Ulrik11Respiratory Section, Internal Medicine Unit, 2Department of Obstetrics and Gynaecology, Hvidovre Hospital and University of Copenhagen, Hvidovre, DenmarkAim and methods: Obesity is a major health problem, and obesity is associated with a high incidence of asthma and poor asthma control. The aim of the present paper is to systematically review the current knowledge of the effect on overall asthma control of weight reduction in overweight and obese adults with asthma.Results: Weight loss in obese individuals with doctor-diagnosed asthma is associated with a 48%–100% remission of asthma symptoms and use of asthma medication. Published studies, furthermore, reveal that weight loss in obese asthmatics improves asthma control, and that especially surgically induced weight loss results in significant improvements in asthma severity, use of asthma medication, dyspnoea, exercise tolerance, and acute exacerbations, including hospitalizations due to asthma. Furthermore, weight loss in obese asthmatics is associated with improvements in level of lung function and airway responsiveness to inhaled methacholine, whereas no significant improvements have been observed in exhaled nitric oxide or other markers of eosinophilic airway inflammation.Conclusion: Overweight and obese adults with asthma experience a high symptomatic remission rate and significant improvements in asthma control, including objective measures of disease activity, after weight loss. Although these positive effects of weight loss on asthma-related health outcomes seem not to be accompanied by remission or improvements in markers of eosinophilic airway inflammation, it has potentially important implications for the future burden of asthma.Keywords: asthma, weight loss, diet, bariatric surgery, asthma control

  14. Electrical Drive Radiated Emissions Estimation in Terms of Input Control Using Extreme Learning Machines

    Directory of Open Access Journals (Sweden)

    A. Wefky

    2012-01-01

    Full Text Available With the increase of electrical/electronic equipment integration complexity, the electromagnetic compatibility (EMC becomes one of the key points to be respected in order to meet the constructor standard conformity. Electrical drives are known sources of electromagnetic interferences due to the motor as well as the related power electronics. They are the principal radiated emissions source in automotive applications. This paper shows that there is a direct relationship between the input control voltage and the corresponding level of radiated emissions. It also introduces a novel model using artificial intelligence techniques for estimating the radiated emissions of a DC-motor-based electrical drive in terms of its input voltage. Details of the training and testing of the developed extreme learning machine (ELM are described. Good agreement between the electrical drive behavior and the developed model is observed.

  15. Associations between inhibitory control and body weight in German primary school children.

    Science.gov (United States)

    Wirt, Tamara; Hundsdörfer, Verena; Schreiber, Anja; Kesztyüs, Dorothea; Steinacker, Jürgen M

    2014-01-01

    Deficits in inhibitory control are supposed to be a risk factor for overweight but literature concerning childhood and beyond the clinical setting is scarce. The objective of this study was to investigate the role of inhibitory control in regards to body weight in a large non-clinical sample of primary school children. Baseline data of 498 children (1st and 2nd grade; 7.0 ± 0.6 years; 49.8% boys) participating in a school-based intervention study in Germany were used. Children performed a Go-Nogo-task to assess inhibitory control. Height and weight were collected and converted to BMI percentiles based on national standards. Relevant influencing factors (sociodemographic data, health characteristics of parents, children's health behaviour) were assessed via parental questionnaire. Inhibitory control was significantly associated with body weight and contributed to the statistical prediction of body weight above and beyond parent education, migration background, parent weight, TV consumption and breakfast habits. Moreover, obese children displayed significantly lower inhibitory control compared to non-overweight and overweight children. The findings suggest that deficits in inhibitory control constitute a risk factor for paediatric obesity. © 2013.

  16. Weight misperception and disordered weight control behaviors among U.S. high school students with overweight and obesity: Associations and trends, 1999-2013.

    Science.gov (United States)

    Hazzard, Vivienne M; Hahn, Samantha L; Sonneville, Kendrin R

    2017-08-01

    To examine prevalence of weight misperception (incongruence between one's perceived weight status and one's actual weight status) and disordered weight control behaviors (DWCBs; unhealthy behaviors aiming to control or modify weight), associations between weight misperception and DWCBs, and temporal trends in prevalence and associations among adolescents with overweight and obesity from 1999 to 2013. Self-reported data from eight biennial cycles (1999-2013) of the cross-sectional national Youth Risk Behavior Survey were used in analyses restricted to respondents with overweight/obesity. Data on weight status perception, use of fasting, purging, and diet pills to control weight, sex, race/ethnicity, and grade in school were used in multivariate logistic regression models. Among U.S. high school students with overweight and obesity, no linear temporal trends were detected for prevalence of weight misperception, fasting, or purging between 1999 and 2013, while a significant linear decrease was observed for prevalence of diet pill use between 1999 and 2013 (b=-0.81, poverweight and obesity, weight misperception appears to be a robust protective factor for DWCBs. Copyright © 2017. Published by Elsevier Ltd.

  17. A Randomized, Controlled Trial of Mirror Therapy for Upper Extremity Phantom Limb Pain in Male Amputees

    Directory of Open Access Journals (Sweden)

    Sacha B. Finn

    2017-07-01

    Full Text Available ObjectivePhantom limb pain (PLP is prevalent in patients post-amputation and is difficult to treat. We assessed the efficacy of mirror therapy in relieving PLP in unilateral, upper extremity male amputees.MethodsFifteen participants from Walter Reed and Brooke Army Medical Centers were randomly assigned to one of two groups: mirror therapy (n = 9 or control (n = 6, covered mirror or mental visualization therapy. Participants were asked to perform 15 min of their assigned therapy daily for 5 days/week for 4 weeks. The primary outcome was pain as measured using a 100-mm Visual Analog Scale.ResultsSubjects in the mirror therapy group had a significant decrease in pain scores, from a mean of 44.1 (SD = 17.0 to 27.5 (SD = 17.2 mm (p = 0.002. In addition, there was a significant decrease in daily time experiencing pain, from a mean of 1,022 (SD = 673 to 448 (SD = 565 minutes (p = 0.003. By contrast, the control group had neither diminished pain (p = 0.65 nor decreased overall time experiencing pain (p = 0.49. A pain decrement response seen by the 10th treatment session was predictive of final efficacy.ConclusionThese results confirm that mirror therapy is an effective therapy for PLP in unilateral, upper extremity male amputees, reducing both severity and duration of daily episodes.RegistrationNCT0030144 ClinicalTrials.gov.

  18. A Randomized, Controlled Trial of Mirror Therapy for Upper Extremity Phantom Limb Pain in Male Amputees.

    Science.gov (United States)

    Finn, Sacha B; Perry, Briana N; Clasing, Jay E; Walters, Lisa S; Jarzombek, Sandra L; Curran, Sean; Rouhanian, Minoo; Keszler, Mary S; Hussey-Andersen, Lindsay K; Weeks, Sharon R; Pasquina, Paul F; Tsao, Jack W

    2017-01-01

    Phantom limb pain (PLP) is prevalent in patients post-amputation and is difficult to treat. We assessed the efficacy of mirror therapy in relieving PLP in unilateral, upper extremity male amputees. Fifteen participants from Walter Reed and Brooke Army Medical Centers were randomly assigned to one of two groups: mirror therapy (n = 9) or control (n = 6, covered mirror or mental visualization therapy). Participants were asked to perform 15 min of their assigned therapy daily for 5 days/week for 4 weeks. The primary outcome was pain as measured using a 100-mm Visual Analog Scale. Subjects in the mirror therapy group had a significant decrease in pain scores, from a mean of 44.1 (SD = 17.0) to 27.5 (SD = 17.2) mm (p = 0.002). In addition, there was a significant decrease in daily time experiencing pain, from a mean of 1,022 (SD = 673) to 448 (SD = 565) minutes (p = 0.003). By contrast, the control group had neither diminished pain (p = 0.65) nor decreased overall time experiencing pain (p = 0.49). A pain decrement response seen by the 10th treatment session was predictive of final efficacy. These results confirm that mirror therapy is an effective therapy for PLP in unilateral, upper extremity male amputees, reducing both severity and duration of daily episodes. NCT0030144 ClinicalTrials.gov.

  19. Patterns of success: online self-monitoring in a web-based behavioral weight control program.

    Science.gov (United States)

    Krukowski, Rebecca A; Harvey-Berino, Jean; Bursac, Zoran; Ashikaga, Taka; West, Delia Smith

    2013-02-01

    Online weight control technologies could reduce barriers to treatment, including increased ease and convenience of self-monitoring. Self-monitoring consistently predicts outcomes in behavioral weight loss programs; however, little is known about patterns of self-monitoring associated with success. The current study examines 161 participants (92% women; 31% African American; mean body mass index = 35.7 ± 5.7) randomized to a 6-month online behavioral weight control program that offered weekly group "chat" sessions and online self-monitoring. Self-monitoring log-ins were continuously monitored electronically during treatment and examined in association with weight change and demographics. Weekend and weekday log-ins were examined separately and length of periods of continuous self-monitoring were examined. We found that 91% of participants logged in to the self-monitoring webpage at least once. Over 6 months, these participants monitored on an average of 28% of weekdays and 17% of weekend days, with most log-ins earlier in the program. Women were less likely to log-in, and there were trends for greater self-monitoring by older participants. Race, education, and marital status were not significant predictors of self-monitoring. Both weekday and weekend log-ins were significant independent predictors of weight loss. Patterns of consistent self-monitoring emerged early for participants who went on to achieve greater than a 5% weight loss. Patterns of online self-monitoring were strongly associated with weight loss outcomes. These results suggest a specific focus on consistent self-monitoring early in a behavioral weight control program might be beneficial for achieving clinically significant weight losses.

  20. The role of protein and carbohydrates for long-term weight control

    DEFF Research Database (Denmark)

    Perez-Cornago, Aurora; van Baak, Marleen A.; Saris, Wim H. M.;

    2014-01-01

    , controlled dietary intervention study, which investigated the role of dietary protein and glycemic index (GI) on weight maintenance in overweight/obese European families. For 6 months, families were randomly assigned to five ad libitum weight-maintenance diets: lowprotein (LP)/low-GI (LGI), LP/high-GI (HGI......Current therapies to manage obesity are based on energy restriction and physical activity promotion. However, the role of specific dietary components for long-term weight maintenance is under debate. This review aims to illustrate some lessons from the pan-European Diogenes study, a randomized......), high-protein (HP)/LGI, HP/HGI, and a control diet. The main result was that the HP/LGI diet was more successful for maintaining weight loss, and has beneficial effects on cardiometabolic risks. Outcomes regarding gender, age, the model of delivery, genetic factors, and benefits on insulin sensitivity...

  1. Frequency-Weighted Model Predictive Control of Trailing Edge Flaps on a Wind Turbine Blade

    DEFF Research Database (Denmark)

    Castaignet, Damien; Couchman, Ian; Poulsen, Niels Kjølstad;

    2013-01-01

    This paper presents the load reduction achieved with trailing edge flaps during a full-scale test on a Vestas V27 wind turbine. The trailing edge flap controller is a frequency-weighted linear model predictive control (MPC) where the quadratic cost consists of costs on the zero-phase filtered...

  2. Effects of Behavioral Weight Control Intervention on Binge Eating Symptoms among Overweight Adolescents

    Science.gov (United States)

    Mehlenbeck, Robyn S.; Jelalian, Elissa; Lloyd-Richardson, Elizabeth E.; Hart, Chantelle N.

    2009-01-01

    This study examined change in binge eating symptoms reported by moderately overweight adolescents following participation in a behavioral weight control intervention. A total of 194 adolescents across two randomized controlled trials participated. Adolescents in both study samples endorsed a mild level of binge eating symptoms at baseline. Results…

  3. Impulse control in the dorsolateral prefrontal cortex counteracts post-diet weight regain in obesity.

    Science.gov (United States)

    Weygandt, Martin; Mai, Knut; Dommes, Esther; Ritter, Kerstin; Leupelt, Verena; Spranger, Joachim; Haynes, John-Dylan

    2015-04-01

    A variety of studies suggest that efficient treatments to induce short-term dietary success in obesity exist. However, sustained maintenance of reduced weight is rare as a large proportion of patients start to regain weight when treatment is discontinued. Thus, from a clinical perspective, it would be desirable to identify factors that counteract post-diet weight regain across longer time-scales. To address this question, we extended our previous work on neural impulse control mechanisms of short-term dietary success in obesity and now investigated the mechanisms counteracting long-term weight regain after a diet. Specifically, we measured neural impulse control during a delay discounting task with fMRI at two time points, i.e. the beginning ('T0') and the end ('T12') of a one-year follow-up interval after a 12-week diet. Then, we tested whether activity in the dorsolateral prefrontal cortex (DLPFC) at T0 and whether activity changes across the follow-up period (T0-T12) are linked to success in weight maintenance. The analyses conducted show that control-related DLPFC activity at T0 was coupled to the degree of success in weight maintenance. Consistently, also behavioral measures of control were linked to the degree of success in maintenance. A direct comparison of neural and behavioral control parameters for prognostic weight change modeling revealed that neural signals were more informative. Taken together, neural impulse control in the DLPFC measured with fMRI directly after a diet predicts real-world diet success in obese patients across extended time periods. Copyright © 2015 Elsevier Inc. All rights reserved.

  4. Controls on fluvial metamorphosis during global warming at the Paleocene-Eocene boundary (56 Ma) in Spain: extreme droughts, extreme floods or both?

    Science.gov (United States)

    Castelltort, Sebastien; Chen, Chen; Guerit, Laure; Foreman, Brady; Paola, Chris; Adatte, Thierry

    2017-04-01

    How does global warming change the frequency and intensity of extreme weather events? The response to this question is partly preserved in the geological record. 56 Ma ago, global temperatures increased during the Paleocene-Eocene Thermal Maximum (PETM), leading to a major biotic turnover, but how this event affected the nature of extreme events remains unknown. On several continents, fluvial systems with sinuous channels within fine-grained floodplains suddenly transformed at the P-E boundary into apparently coarser-grained braid plains with frequent lateral migrations, washing their muddy floodplains to the seas. This landscape transformation has been related to aridification and intensification of precipitation allowing transport of coarser material as a result of P-E global warming, with important implications for predicting the consequences of current global change. Here we test this hypothesis by quantifying the magnitude of grain size change and flow depth at a representative P-E locality in Northern Spain. We find that the size of pebbles in transport and flow depth remained similar to, or even smaller than, pre-PETM conditions. This suggests that, if more seasonal and extreme precipitation occurred, they are not necessarily borne out in the predicted deeper flow depths and coarser grain sizes, but rather trigger a shift to multiple active channels. However, an alternative or complementary explanation may rest in pollen data found in coeval marine records and which document a dramatic vegetation shift from permanent conifer forests prior to the crisis into periodic vegetation in brief periods of rain during the hyperthermal episode. Such change induced by long periods of intense droughts, could have enhanced erodibility of channel banks by decreasing root-controlled cohesion of fine-grained floodplains and interfluves, promoting their lateral mobility and the observed fluvial metamorphosis. Thus, although water is regarded as the main agent sculpting

  5. A smartphone-supported weight loss program: design of the ENGAGED randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Pellegrini Christine A

    2012-11-01

    Full Text Available Abstract Background Obesity remains a major public health challenge, demanding cost-effective and scalable weight management programs. Delivering key treatment components via mobile technology offers a potential way to reduce expensive in-person contact, thereby lowering the cost and burden of intensive weight loss programs. The ENGAGED study is a theory-guided, randomized controlled trial designed to examine the feasibility and efficacy of an abbreviated smartphone-supported weight loss program. Methods/design Ninety-six obese adults (BMI 30–39.9 kg/m2 will be randomized to one of three treatment conditions: (1 standard behavioral weight loss (STND, (2 technology-supported behavioral weight loss (TECH; or (3 self-guided behavioral weight loss (SELF. All groups will aim to achieve a 7% weight loss goal by reducing calorie and fat intake and progressively increasing moderate intensity physical activity to 175 minutes/week. STND and TECH will attend 8 group sessions and receive regular coaching calls during the first 6 months of the intervention; SELF will receive the Group Lifestyle Balance Program DVD’s and will not receive coaching calls. During months 1–6, TECH will use a specially designed smartphone application to monitor dietary intake, body weight, and objectively measured physical activity (obtained from a Blue-tooth enabled accelerometer. STND and SELF will self-monitor on paper diaries. Linear mixed modeling will be used to examine group differences on weight loss at months 3, 6, and 12. Self-monitoring adherence and diet and activity goal attainment will be tested as mediators. Discussion ENGAGED is an innovative weight loss intervention that integrates theory with emerging mobile technologies. We hypothesize that TECH, as compared to STND and SELF, will result in greater weight loss by virtue of improved behavioral adherence and goal achievement. Trial registration NCT01051713

  6. Control of coherent excitation of neon in the extreme ultraviolet regime.

    Science.gov (United States)

    Plenge, Jürgen; Wirsing, Andreas; Raschpichler, Christopher; Wassermann, Bernhard; Rühl, Eckart

    2011-01-01

    Coherent excitation of a superposition of Rydberg states in neon by the 13th harmonic of an intense 804 nm pulse and the formation of a wave packet is reported. Pump-probe experiments are performed, where the 3d-manifold of the 2p6-->2p5 (2P3/2) 3d [1/2]1- and 2p6-->2p5 (2P3/2) 3d [3/2]1-transitions are excited by an extreme ultraviolet (XUV) radiation pulse, which is centered at 20.05 eV photon energy. The temporal evolution of the excited state population is probed by ionization with a time-delayed 804 nm pulse. Control of coherent transient excitation and wave packet dynamics in the XUV-regime is demonstrated, where the spectral phase of the 13th harmonic is used as a control parameter. Modulation of the phase is achieved by propagation of the XUV-pulse through neon of variable gas density. The experimental results indicate that phase-shaped high-order harmonics can be used to control fundamental coherent excitation processes in the XUV-regime.

  7. Carbohydrate intake and glycemic index affect substrate oxidation during a controlled weight cycle in healthy men.

    Science.gov (United States)

    Kahlhöfer, J; Lagerpusch, M; Enderle, J; Eggeling, B; Braun, W; Pape, D; Müller, M J; Bosy-Westphal, A

    2014-09-01

    Because both, glycemic index (GI) and carbohydrate content of the diet increase insulin levels and could thus impair fat oxidation, we hypothesized that refeeding a low GI, moderate-carbohydrate diet facilitates weight maintenance. Healthy men (n=32, age 26.0±3.9 years; BMI 23.4±2.0 kg/m(2)) followed 1 week of controlled overfeeding, 3 weeks of caloric restriction and 2 weeks of hypercaloric refeeding (+50, -50 and +50% energy requirement) with low vs high GI (41 vs 74) and moderate vs high CHO intake (50% vs 65% energy). We measured adaptation of fasting macronutrient oxidation and the capacity to supress fat oxidation during an oral glucose tolerance test. Changes in fat mass were measured by quantitative magnetic resonance. During overfeeding, participants gained 1.9±1.2 kg body weight, followed by a weight loss of -6.3±0.6 kg and weight regain of 2.8±1.0 kg. Subjects with 65% CHO gained more body weight compared with 50% CHO diet (Pregain in fat mass (r=0.43, Pweight (r=0.35; P=0.051). Both higher GI and higher carbohydrate content affect substrate oxidation and thus the regain in body weight in healthy men. These results argue in favor of a lower glycemic load diet for weight maintenance after weight loss.

  8. An Evaluation of a Smartphone–Assisted Behavioral Weight Control Intervention for Adolescents: Pilot Study

    Science.gov (United States)

    Duncombe, Kristina M; Lott, Mark A; Hunsaker, Sanita L; Duraccio, Kara M; Woolford, Susan J

    2016-01-01

    Background The efficacy of adolescent weight control treatments is modest, and effective treatments are costly and are not widely available. Smartphones may be an effective method for delivering critical components of behavioral weight control treatment including behavioral self-monitoring. Objective To examine the efficacy and acceptability of a smartphone assisted adolescent behavioral weight control intervention. Methods A total of 16 overweight or obese adolescents (mean age=14.29 years, standard deviation=1.12) received 12 weeks of combined treatment that consisted of weekly in-person group behavioral weight control treatment sessions plus smartphone self-monitoring and daily text messaging. Subsequently they received 12 weeks of electronic-only intervention, totaling 24 weeks of intervention. Results On average, participants attained modest but significant reductions in body mass index standard score (zBMI: 0.08 standard deviation units, t (13)=2.22, P=.04, d=0.63) over the in-person plus electronic-only intervention period but did not maintain treatment gains over the electronic-only intervention period. Participants self-monitored on approximately half of combined intervention days but less than 20% of electronic-only intervention days. Conclusions Smartphones likely hold promise as a component of adolescent weight control interventions but they may be less effective in helping adolescents maintain treatment gains after intensive interventions. PMID:27554704

  9. Effects of a Worksite Weight-Control Programme in Obese Male Workers: A Randomized Controlled Crossover Trial

    Science.gov (United States)

    Iriyama, Yae; Murayama, Nobuko

    2014-01-01

    Objective: We conducted a randomized controlled crossover trial to evaluate the effects of a new worksite weight-control programme designed for men with or at risk of obesity using a combination of nutrition education and nutrition environmental interventions. Subjects and methods: Male workers with or at risk of obesity were recruited for this…

  10. Reduced-calorie dietary weight loss, exercise, and sex hormones in postmenopausal women: randomized controlled trial.

    Science.gov (United States)

    Campbell, Kristin L; Foster-Schubert, Karen E; Alfano, Catherine M; Wang, Chia-Chi; Wang, Ching-Yun; Duggan, Catherine R; Mason, Caitlin; Imayama, Ikuyo; Kong, Angela; Xiao, Liren; Bain, Carolyn E; Blackburn, George L; Stanczyk, Frank Z; McTiernan, Anne

    2012-07-01

    Estrogens and androgens are elevated in obesity and associated with increased postmenopausal breast cancer risk, but the effect of weight loss on these biomarkers is unknown. We evaluated the individual and combined effects of a reduced-calorie weight loss diet and exercise on serum sex hormones in overweight and obese postmenopausal women. We conducted a single-blind, 12-month, randomized controlled trial from 2005 to 2009. Participants (age 50 to 75 years; body mass index > 25.0 kg/m(2), exercising exercise ("exercise"; n = 117), (3) combined reduced-calorie weight loss diet and moderate- to vigorous-intensity aerobic exercise ("diet + exercise"; n = 117), or (4) control (n = 87). Outcomes were estrone concentration (primary) and estradiol, free estradiol, total testosterone, free testosterone, androstenedione, and sex hormone-binding globulin (SHBG) concentrations (secondary). Mean age and body mass index were 58 years and 30.9 kg/m(2), respectively. Compared with controls, estrone decreased 9.6% (P = .001) with diet, 5.5% (P = .01) with exercise, and 11.1% (P exercise. Estradiol decreased 16.2% (P exercise, and 20.3% (P exercise. SHBG increased 22.4% (P exercise. Free estradiol decreased 21.4% (P exercise. Free testosterone decreased 10.0% (P exercise. Greater weight loss produced stronger effects on estrogens and SHBG. Weight loss significantly lowered serum estrogens and free testosterone, supporting weight loss for risk reduction through lowering exposure to breast cancer biomarkers.

  11. Satiety and body weight control. Promise and compromise. Comment on 'Satiety. No way to slim'.

    Science.gov (United States)

    Bellisle, France; Tremblay, Angelo

    2011-12-01

    Satiety is a complex psycho-physiological mechanism that allows the adjustment of energy intake to expenditures. As such, it plays an important role among the numerous interacting mechanisms contributing to body weight control. Booth and Nouwen rightfully stress that satiety claims can be misleading and even dangerous when they are misrepresented or misinterpreted as slimming claims. Indeed, a substance that might enhance satiety, especially by affecting sensations on the short term, will not necessarily help to decrease energy intake on the longer term or facilitate weight loss. While denouncing abusive claims, the article by Booth and Nouwen also refers to numerous contributions of satiety mechanisms that could potentially affect intake and weight control over the long term. We propose that multi-step proofs of concepts could be useful in this field. Satiety effects are one early step in a complex demonstration of how a substance could affect short-term intake, hormonal mechanisms, and medium or long term changes in body weight. An example of such a step-wise process is described (beneficial effects of calcium and dairy products on appetite and weight change). Booth and Nouwen insist that satiety effects should be evaluated in the context of the local socio-cultural meal pattern and lifestyle. This wise advice supports the use of multi-step proofs of concept, perhaps including the use of biomarkers as well as behavioural measures, before any satiety enhancement claim can be considered to have any actual impact on body weight control.

  12. Pinning weighted complex networks with heterogeneous delays by a small number of feedback controllers

    Institute of Scientific and Technical Information of China (English)

    XIANG LinYing; LIU ZhongXin; CHEN ZengQiang; YUAN ZhuZhi

    2008-01-01

    Weighted complex dynamical networks with heterogeneous delays in both con-tinuous-time and discrete-time domains are controlled by applying local feedback injections to a small fraction of network nodes. Some generic stability criteria en-suring delay-independent stability are derived for such controlled networks in terms of linear matrix inequalities (LMIs), which guarantee that by placing a small number of feedback controllers on some nodes the whole network can be pinned to some desired homogenous states. In some particular cases, a single controller can achieve the control objective. It is found that stabilization of such pinned networks is completely determined by the dynamics of the individual uncoupled node, the overall coupling strength, the inner-coupling matrix, and the smallest eigenvalue of the coupling and control matrix. Numerical simulations of a weighted network composing of a 3-dimensional nonlinear system are finally given for illustration and verification.

  13. Vegetarian Diets and Weight Reduction: a Meta-Analysis of Randomized Controlled Trials.

    Science.gov (United States)

    Huang, Ru-Yi; Huang, Chuan-Chin; Hu, Frank B; Chavarro, Jorge E

    2016-01-01

    Vegetarian diets may promote weight loss, but evidence remains inconclusive. PubMed, EMBASE and UpToDate databases were searched through September 22, 2014, and investigators extracted data regarding study characteristics and assessed study quality among selected randomized clinical trials. Population size, demographic (i.e., gender and age) and anthropometric (i.e., body mass index) characteristics, types of interventions, follow-up periods, and trial quality (Jadad score) were recorded. The net changes in body weight of subjects were analyzed and pooled after assessing heterogeneity with a random effects model. Subgroup analysis was performed based on type of vegetarian diet, type of energy restriction, study population, and follow-up period. Twelve randomized controlled trials were included, involving a total of 1151 subjects who received the intervention over a median duration of 18 weeks. Overall, individuals assigned to the vegetarian diet groups lost significantly more weight than those assigned to the non-vegetarian diet groups (weighted mean difference, -2.02 kg; 95 % confidence interval [CI]: -2.80 to -1.23). Subgroup analysis detected significant weight reduction in subjects consuming a vegan diet (-2.52 kg; 95 % CI: -3.02 to -1.98) and, to a lesser extent, in those given lacto-ovo-vegetarian diets (-1.48 kg; 95 % CI: -3.43 to 0.47). Studies on subjects consuming vegetarian diets with energy restriction (ER) revealed a significantly greater weight reduction (-2.21 kg; 95 % CI: -3.31 to -1.12) than those without ER (-1.66 kg; 95 % CI: -2.85 to -0.48). The weight loss for subjects with follow-up of Vegetarian diets appeared to have significant benefits on weight reduction compared to non-vegetarian diets. Further long-term trials are needed to investigate the effects of vegetarian diets on body weight control.

  14. Hyaluronan molecular weight is controlled by UDP-N-acetylglucosamine concentration in Streptococcus zooepidemicus.

    Science.gov (United States)

    Chen, Wendy Yiting; Marcellin, Esteban; Hung, Jacky; Nielsen, Lars Keld

    2009-07-03

    The molecular weight of hyaluronan is important for its rheological and biological function. The molecular mechanisms underlying chain termination and hence molecular weight control remain poorly understood, not only for hyaluronan synthases but also for other beta-polysaccharide synthases, e.g. cellulose, chitin, and 1,3-betaglucan synthases. In this work, we manipulated metabolite concentrations in the hyaluronan pathway by overexpressing the five genes of the hyaluronan synthesis operon in Streptococcus equi subsp. zooepidemicus. Overexpression of genes involved in UDP-glucuronic acid biosynthesis decreased molecular weight, whereas overexpression of genes involved in UDP-N-acetylglucosamine biosynthesis increased molecular weight. The highest molecular mass observed was at 3.4 +/- 0.1 MDa twice that observed in the wild-type strain, 1.8 +/- 0.1 MDa. The data indicate that (a) high molecular weight is achieved when an appropriate balance of UDP-N-acetylglucosamine and UDP-glucuronic acid is achieved, (b) UDP-N-acetylglucosamine exerts the dominant effect on molecular weight, and (c) the wild-type strain has suboptimal levels of UDP-N-acetylglucosamine. Consistent herewith molecular weight correlated strongly (rho = 0.84, p = 3 x 10(-5)) with the concentration of UDP-N-acetylglucosamine. Data presented in this paper represent the first model for hyaluronan molecular weight control based on the concentration of activated sugar precursors. These results can be used to engineer strains producing high molecular weight hyaluronan and may provide insight into similar polymerization mechanisms in other polysaccharides.

  15. Psychological control by parents is associated with a higher child weight.

    Science.gov (United States)

    Rodenburg, Gerda; Kremers, Stef P J; Oenema, Anke; van de Mheen, Dike

    2011-10-01

    In this examination of the association between parenting style and child weight, the neglected concept of 'psychological control' has been added to the generally accepted parenting dimensions 'support' and 'behavioural control'. Also explored is whether the potential association between parenting and child weight is moderated by socio-demographic variables (child's age/ethnicity, and parent's education level). A cross-sectional study was performed among 1,665 parent-child dyads. The children's mean age was 8 years. Their height and weight were measured to calculate their body mass index (BMI). Parents completed a questionnaire to measure the three parenting dimensions. Based on these dimensions, five parenting styles were defined: the authoritative, permissive, authoritarian, neglecting and rejecting parenting style. Child BMI z-scores were regressed on parenting style, adjusting for parental BMI, child ethnicity, and parent's education level. Rejecting parenting, characterized by high psychological control, low support and low behavioural control, is the only parenting style significantly related to child BMI z-scores (β = 0.074, p parenting, this study has further elucidated the mechanisms whereby parenting may affect child weight. Demonstrating that 'rejecting parenting' is associated with a higher child weight, emphasizes the need for longitudinal studies in which parenting style is measured three-dimensionally. Potential mediating effects of parental feeding style and children's eating style, as well as age moderation, should be included in these studies.

  16. Theoretical and baseline considerations for diet and weight control of diabetes among blacks.

    Science.gov (United States)

    Kumanyika, S K; Ewart, C K

    1990-11-01

    This article outlines theoretical considerations for diet and weight control of non-insulin-dependent diabetes mellitus (NIDDM) and identifies factors that may be of particular importance in influencing the success of diet and weight control of NIDDM in the Black population. Long-term adherence to dietary or weight-control regimens requires that the patient evaluate and restructure established eating and physical activity patterns. With the use of the social action theory as a conceptual framework, this complex behavioral change task can be understood as a function of the interplay of various self-regulatory mechanisms. These mechanisms are influenced by the person's capabilities for making changes, his/her physical condition and general health status, the physical and social environmental context, and the person's material and social resources. Many of these factors may differ for Blacks and Whites in a direction that suggests a lesser potential for effective diet and weight-loss therapy among Black NIDDM patients. For example, compared with Whites, Blacks are more likely to have limited incomes, low educational attainment, ambivalence about weight control, multiple health problems, and high-fat high-sodium low-fiber diets or food preferences. However, some evidence suggests that state-of-the-art counseling approaches can be as effective for Blacks as for Whites. The challenge is to adapt the types of approaches suggested by the social action theory for culturally appropriate and cost-effective delivery in Black community health-care settings.

  17. Investigation of postural edema in the lower extremities of traffic control workers

    Directory of Open Access Journals (Sweden)

    Ana Paula Nunes Pereira Brito

    2013-12-01

    Full Text Available OBJECTIVE: Determine the prevalence of postural edema and investigate whether working posture - sitting down or standing up - affect its frequency. METHODS: Sixteen traffic control agents were assessed by water displacement volumetry and the results were analyzed in two groups, depending on working posture. Those who worked standing up for more than 4 hours were allocated to the SU group and those who worked sitting down for more than 4 hours were allocated to the SD group. Each worker was assessed before and after their working shift for three consecutive days. Data were analyzed using ANOVA and the test of equality of two proportions. The significance level was set at p ≤ 0.05. The assessment showed that members of both groups had postural edema of the lower extremities (p ≤ 0.001. RESULTS: When the frequency of postural edema was compared across groups, a trend was observed for greater edema formation in the SU group than in the SD group, although without statistically significant difference. CONCLUSION: It was concluded that traffic control agents suffer postural edema after 4 hours working in either of the postures investigated although with a predominance of edema formation among those who work standing up.

  18. 超低出生体重儿呼吸管理的研究进展%Advance in the respiratory management of extremely low birth weight infants

    Institute of Scientific and Technical Information of China (English)

    黄文娣

    2014-01-01

    随着辅助生育技术及新生儿重症监护室的发展,超低出生体重儿存活率逐渐增加.由于超低出生体重儿肺发育不成熟,一些产前干预、复苏策略及产后的呼吸管理对于该类患儿长期存活及远期预后具有重要意义.无创性呼吸支持策略可以减少机械通气产生的气压伤、容量伤及氧化应激损伤.吸入性NO、体外膜肺等呼吸支持策略还有待深入研究.%With the improvement of assisted reproductive technology and neonatal intensive care unit,the extremely low birth weight infants have increasingly survived.Since the immature pulmonary,antenatal interventions,resuscitation techniques and postnatal respiratory management attribute to their survival and long term outcomes.Non-invasive ventilation minimize barotrauma,volutrauma and oxygen toxicity induced by mechanical ventilation.Other new strategy such asinhaled NO,extracorporeal membrane oxygenation will be explored.

  19. An Efficient Diagnosis System for Parkinson’s Disease Using Kernel-Based Extreme Learning Machine with Subtractive Clustering Features Weighting Approach

    Directory of Open Access Journals (Sweden)

    Chao Ma

    2014-01-01

    Full Text Available A novel hybrid method named SCFW-KELM, which integrates effective subtractive clustering features weighting and a fast classifier kernel-based extreme learning machine (KELM, has been introduced for the diagnosis of PD. In the proposed method, SCFW is used as a data preprocessing tool, which aims at decreasing the variance in features of the PD dataset, in order to further improve the diagnostic accuracy of the KELM classifier. The impact of the type of kernel functions on the performance of KELM has been investigated in detail. The efficiency and effectiveness of the proposed method have been rigorously evaluated against the PD dataset in terms of classification accuracy, sensitivity, specificity, area under the receiver operating characteristic (ROC curve (AUC, f-measure, and kappa statistics value. Experimental results have demonstrated that the proposed SCFW-KELM significantly outperforms SVM-based, KNN-based, and ELM-based approaches and other methods in the literature and achieved highest classification results reported so far via 10-fold cross validation scheme, with the classification accuracy of 99.49%, the sensitivity of 100%, the specificity of 99.39%, AUC of 99.69%, the f-measure value of 0.9964, and kappa value of 0.9867. Promisingly, the proposed method might serve as a new candidate of powerful methods for the diagnosis of PD with excellent performance.

  20. The NULevel trial of a scalable, technology-assisted weight loss maintenance intervention for obese adults after clinically significant weight loss: study protocol for a randomised controlled trial.

    Science.gov (United States)

    Evans, Elizabeth H; Araújo-Soares, Vera; Adamson, Ashley; Batterham, Alan M; Brown, Heather; Campbell, Miglena; Dombrowski, Stephan U; Guest, Alison; Jackson, Daniel; Kwasnicka, Dominika; Ladha, Karim; McColl, Elaine; Olivier, Patrick; Rothman, Alexander J; Sainsbury, Kirby; Steel, Alison J; Steen, Ian Nicholas; Vale, Luke; White, Martin; Wright, Peter; Sniehotta, Falko F

    2015-09-22

    Effective weight loss interventions are widely available but, after weight loss, most individuals regain weight. This article describes the protocol for the NULevel trial evaluating the effectiveness and cost-effectiveness of a systematically developed, inexpensive, scalable, technology-assisted, behavioural intervention for weight loss maintenance (WLM) in obese adults after initial weight loss. A 12-month single-centre, two-armed parallel group, participant randomised controlled superiority trial is underway, recruiting a total of 288 previously obese adults after weight loss of ≥5 % within the previous 12 months. Participants are randomly assigned to intervention or control arms, with a 1:1 allocation, stratified by sex and percentage of body weight lost (costs. Participants in the intervention arm initially attend an individual face-to-face WLM consultation with an intervention facilitator and then use a mobile internet platform to self-monitor and report their diet, daily activity (via pedometer) and weight through daily weighing on wirelessly connected scales. Automated feedback via mobile phone, tailored to participants' weight regain and goal progress is provided. Participants in the control arm receive quarterly newsletters (via links embedded in text messages) and wirelessly connected scales. Qualitative process evaluation interviews are conducted with a subsample of up to 40 randomly chosen participants. Acceptability and feasibility of procedures, cost-effectiveness, and relationships among socioeconomic variables and WLM will also be assessed. It is hypothesised that participants allocated to the intervention arm will show significantly lower levels of weight regain from baseline than those in the control arm. To date, this is the first WLM trial using remote real-time weight monitoring and mobile internet platforms to deliver a flexible, efficient and scalable intervention, tailored to the individual. This trial addresses a key research need and has

  1. Effect of educational training on nutrition and weight control in under-18 Spanish wrestlers

    OpenAIRE

    Andrea Visiedo; Jose Manuel Palao

    2017-01-01

    Abstract The aim of this study was to investigate the effect of a formative program concerning nutrition, weight control, and its risks wrestlers under the age of 18 (under-18) at the Spanish national level. The sample comprised 36 under-18 wrestlers that were pre-selected for the Spanish national team. A quasi-experimental design with a pre-test and post-test was used. The dependent variableswere the knowledge of nutrition and weight control and its risks. The independent variable was the ed...

  2. Obesity and weight control measures: Findings from female college students of Agra

    Directory of Open Access Journals (Sweden)

    H K Thakkar

    2013-01-01

    Full Text Available Context: Obesity has negative health impacts. Obese people have higher risk of non-communicable diseases (NCDs. Overweight and obesity during young adulthood can track into later adulthood along with its higher risk for NCDs. Aims: To identify the weight control intention and dietary practices used among normal, overweight, and obese college females and to know the reasons for discontinuation among ever tried subjects. Settings and Design : A cross-sectional study conducted in urban and rural colleges of Agra. Materials and Methods: This was a cross-sectional study among 400 female college students. Height and weight were measured to assess body composition according to BMI (Body Mass Index criteria (WHO 2002. Study included a semi-structured and semi-open-ended instrument to assess practices related to weight control. Their responses were collected, tabulated, analyzed, and interpreted. Statistical analysis used: Frequency. Results: The prevalence of overweight and obesity was found to be 18.5% and 4.5%, respectively, according to BMI (WHO 2002. One third of the subjects were recording their weight monthly. Slightly less than half of the subjects (46% were trying to maintain optimum weight. Almost one third of these subjects (33.5% were presently trying to lose weight. About one fifth of total 400 subjects (20.5% were not concerned about their weight status. Majority of the subjects (85% irrespective of their obesity status did not take any professional advice. More than half (52.7% were resorting to physical activity to lose weight. Taking more fruits/vegetables (44.7% was found to be the most common healthy dieting practices and most unhealthy was fasting (15.3%. More than one fourth (28.8% of the subjects abandoned weight control practices because of shortage of time followed by 22.4% due to physical weakness. Conclusions: Collectively, results indicate female college students, regardless of weight status, would benefit from open discussions

  3. Autonomy support and control in weight management: what important others do and say matters.

    Science.gov (United States)

    Ng, Johan Y Y; Ntoumanis, Nikos; Thøgersen-Ntoumani, Cecilie

    2014-09-01

    Drawing from self-determination theory (Ryan & Deci, 2002, Overview of self-determination theory: An organismic-dialectical perspective. In E. L. Deci & R. M. Ryan (Eds.), Handbook of self-determination research (pp. 3-33). Rochester, NY: The University of Rochester Press.), we examined how individuals' psychological needs, motivation, and behaviours (i.e., physical activity and eating) associated with weight management could be predicted by perceptions of their important others' supportive and controlling behaviours. Using a cross-sectional survey design, 235 participants (mean age = 27.39 years, SD = 8.96 years) completed an online questionnaire. Statistical analyses showed that when important others were perceived to be more supportive, participants reported higher levels of more optimal forms of motivation for weight management, which in turn predicted more physical activity and healthy eating behaviours. In contrast, when important others were perceived to be controlling, participants reported higher levels of less optimal forms of motivation, which in turn predicted less physical activity and healthy eating behaviours, as well as more unhealthy eating behaviours. Significant indirect effects were also found from perceived support and control from important others to physical activity and eating behaviours, all in the expected directions. The findings support the importance of important others providing support and refraining from controlling behaviours in order to facilitate motivation and behaviours conducive to successful weight management. What is already known on this subject? Autonomy support is related to basic need satisfaction and autonomous motivation in the context of weight management. In turn, these variables are related to adaptive outcomes for weight management. What does this study add? Measurement of perceived controlling behaviours by important others. Measurement of perceived need thwarting. Structural model on how important others affect

  4. Frequency-Weighting Filter Selection for H2 Control of Microgravity Isolation Systems: A Consideration of the "Implicit Frequency Weighting" Problem

    Science.gov (United States)

    Hampton, R. David; Whorton, Mark S.

    2000-01-01

    Many space-science experiments need an active isolation system to provide them with the requisite microgravity environment. The isolation system planned for use with the International Space Station (ISS) have been appropriately modeled using relative position, relative velocity, and acceleration states. In theory, frequency-weighting design filters can be applied to them state-space models, In order to develop optimal H2 or mixed-norm controllers with desired stability and performance characteristics. In practice. however, since there Is a kinematic relationship among the various states. any frequency weighting applied to one state will implicitly weight other states. These implicit frequency-weighting effects must be considered, for intelligent frequency-weighting filter assignment. This paper suggests a rational approach to the assignment of frequency-weighting design filters, in the presence of the kinematic coupling among states that exists in the microgravity vibration isolation problem.

  5. Scientific Opinion on the essential composition of total diet replacements for weight control

    Directory of Open Access Journals (Sweden)

    EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA

    2015-01-01

    Full Text Available Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA was asked to deliver a scientific opinion on the essential composition of total diet replacements for weight control. Total diet replacements for weight control are intended to induce a substantial energy deficit in overweight or obese adults who wish to lose weight and replace the whole diet in the context of energy-restricted diets for weight reduction. In this opinion, the Panel proposed a minimum protein content based on a Population Reference Intake for protein adjusted for the overweight or obese (75 g/day, a minimum carbohydrate content based on the obligatory glucose demands of the brain (30 g/day and minimum contents of linoleic acid (11 g/day, α-linolenic acid (1.4 g/day and micronutrients based on reference values established either by the Panel or by other scientific or authoritative bodies. Derived from the minimum content of macronutrients, the Panel proposed a minimum energy content of total diet replacements for weight control of 2 510 kJ/day (600 kcal/day. The Panel also advised on potential conditions and restrictions of use for these products.

  6. Lay health educators translate a weight-loss intervention in senior centers: a randomized controlled trial.

    Science.gov (United States)

    West, Delia Smith; Bursac, Zoran; Cornell, Carol E; Felix, Holly C; Fausett, Jennifer K; Krukowski, Rebecca A; Lensing, Shelly; Love, Sharhonda J; Prewitt, T Elaine; Beck, Cornelia

    2011-10-01

    Older adults have high obesity rates and respond well to evidence-based weight-loss programs, such as the Diabetes Prevention Program (DPP) Lifestyle intervention. The goal of this study was to determine whether a translation of the DPP Lifestyle program delivered by lay health educators and conducted in senior centers is effective in promoting weight loss among older adults. An RCT with older adults nested within senior centers. Senior centers identified lay health educators to receive training and deliver the intervention program at the senior center. Senior centers were randomized to DPP Lifestyle program or an attention control intervention (cognitive training). Senior centers (N=15) located throughout Arkansas. Participants (N=228) were obese (BMI=34.5±4.9) older (aged 71.2±6.6 years) adults able to engage in moderate exercise. Follow-up data were collected at 4 months on 93% of the original cohort between February 2009 and July 2010. A 12-session translation of the Diabetes Prevention Program Lifestyle behavioral weight-control program delivered in group sessions by trained lay health educators. Body weight was assessed by digital scale. Percentage weight loss from baseline and proportion achieving ≥5% and ≥7% weight loss were examined. Analyses were completed in March 2011. Participants attending senior centers randomized to Lifestyle lost a significantly greater percentage of baseline weight (3.8%, 95% CI=2.9%, 4.6%) than those in the control senior centers (0.2%, 95% CI= -0.6%, -0.9%) after adjusting for baseline BMI and gender (psenior centers offering the Lifestyle program, 38% lost ≥5% of baseline weight compared with 5% in the control arm (pLifestyle senior centers lost ≥7% than did control participants (3%, p=0.001). A behavioral lifestyle weight-loss intervention delivered by a lay health educator offers a promising vehicle for translation of evidence-based obesity treatment programs in underserved areas. This study is registered at

  7. Automatic Weight Selection Algorithm for Designing H Infinity controller for Active Magnetic Bearing

    Directory of Open Access Journals (Sweden)

    Sarath S Nair

    2011-01-01

    Full Text Available In recent times active magnetic bearing has got wide acceptance in industries and other special systems. Current researches focus on improving the disturbance rejection properties of magnetic bearings towork well in industrial environment. So far many controllers have been developed to control the system, of which the H∞ controller is found to guarantee robustness and performance. In this paper an automatic weight selection algorithm is proposed to design robust H Infinity controller automatically for active magnetic bearing system and detailed disturbance analysis is done. This paper focuses on the controller implementation point of view and analyses the variation in control current, peak responses and steady state error of the developed controller. Comparison with a well tuned PID controller shows the efficacy of H infinity controller designed using the proposed algorithm.

  8. Effect of intrapartum nursing of NICU nurse specialist to rescue extremely low birth weight infants%NICU专科护士产时护理对超低出生体重儿抢救效果的影响

    Institute of Scientific and Technical Information of China (English)

    于新颖; 刘丹妮; 王玲

    2012-01-01

    目的 探讨产时NICU专科护士配合抢救对超低出生体重儿抢救效果的影响.方法 将2008年11月至2012年1月出生的超低出生体重儿按出生单双日分组,单日为观察组30例,产时为NICU专科护士配合抢救和护理;双日为对照组30例,产时是产科接产医生配合抢救,观察配合人员改变后对抢救效果的影响.结果 观察组5 min Apgar评分明显高于对照组[(8.13±0.68)分比(6.73±0.83)分],差异有统计学意义(t=7.152,P<0.01).观察组体温、pH值、BE值明显高于对照组,差异均有统计学意义(t值分别为13.274,6.152,2.691;P均<0.05);抢救时间较对照组缩短[(12.67±2.86) min比(14.33±2.86)min],差异亦有统计学意义(t=-2.260,P<0.05).结论 产时NICU专科护士配合抢救和护理可明显提高超低出生体重儿的抢救效果,缩短抢救时间,为后续治疗奠定基础.%Objective To investigate the rescuing effect of extremely low birth weight infants under the assistance of intrapanrtum NICU nurse specialist.Methods Sixty extremely low birth weight infants born from November 2008 to January 2012 were divided into two groups according to the odd-even date of their birth.30 infants who were born on odd days were the observation group and rescued and nursed by intrapanrtum NICU nurse specialist,while 30 infants who were born on even days were the control group and rescued by obstetric doctors.The effect of personnel change on rescuing was observed and compared.Results In the observation group,5 minute Apgar scorewas significantly higher than that in the control group [(8.13 ±0.68) vs (6.73 ±0.83) (t = 7.152,P < 0.01) ; the body temperature,pH value and BE value were all significantly higher than those in the control group (t = 13.274,6.152,2.691,respectively;P <0.05) ; rescue time was shorter than that of the control group [(12.67 ± 2.86) min vs (14.33 ± 2.86) min] (t =-2.260,P < 0.05).Conclusions The assistance and nursing by

  9. 极低及超低出生体重儿的预后因素分析%Prognostic factors in very low birth weight infants and extremely low birth weight infants

    Institute of Scientific and Technical Information of China (English)

    王恋; 李娟; 毛健; 张静; 陈丹

    2014-01-01

    Objective To analyze the clinical data of very low birth weight infants (VLBWIs) and extremely low birth weight infants (ELBWIs) (birth weight≤1 200 g) and to provide prewarning indicators for prognostic evaluation and clinical intervention. Methods A retrospective analysis was performed on the clinical data of 108 VLBWIs and ELBWIs to investigate the maternal history of diseases during pregnancy, neonatal birth status, the process of diagnosis and treatment, and prognosis. Unconditional logistic regression analysis was used to determine prognostic factors. Results Of the 108 preterm infants, 15 had a birth weight of<800 g, 29 had a birth weight of 800-999 g, and 64 had a birth weight of 1000-1200 g. The mortality was 33.3%(36/108). Placenta previa and Apgar score≤3 at 5 minutes were the main risk factors for death within 24 hours of birth;premature rupture of membrane, Apgar score≤3 at 5 minutes, and pulmonary hemorrhage were the main risk factors for death between 24 hours and 7 days after birth;late-onset sepsis caused by invasive fungal infection was an independent risk factor for death over 7 days after birth, while pregnancy-induced hypertension syndrome was a protective factor. Conclusions The mortality in VLBWIs and ELBWIs is relatively high, and the prognostic factors vary between preterm infants of different ages. Clinicians should discuss management options for the infants on the basis of these ifndings to increase the survival of preterm infants.%目的:分析极低及超低出生体重儿(出生体重≤1200 g)的临床资料,为其预后及临床干预提供预警指标。方法回顾性分析108例极低及超低出生体重儿的母孕期病史、新生儿出生时情况、诊治经过及预后,采用非条件logistic回归分析筛选预后的影响因素。结果108例极低及超低出生体重儿,出生体重范围在<800 g,800~999 g和1000~1200 g的早产儿分别为15例、29例和64例。存活72例,死亡36

  10. An adaptive metamaterial beam with hybrid shunting circuits for extremely broadband control of flexural waves

    Science.gov (United States)

    Chen, Y. Y.; Hu, G. K.; Huang, G. L.

    2016-10-01

    A great deal of research has been devoted to controlling the dynamic behaviors of phononic crystals and metamaterials by directly tuning the frequency regions and/or widths of their inherent band gaps. Here, we report a new class of adaptive metamaterial beams with hybrid shunting circuits to realize super broadband Lamb-wave band gaps at an extreme subwavelength scale. The proposed metamaterial is made of a homogeneous host beam on which tunable local resonators consisting of hybrid shunted piezoelectric stacks with proof masses are attached. The hybrid shunting circuits are composed of negative-capacitance and negative-inductance elements connected in series or in parallel in order to tune the desired frequency-dependent stiffness. It is shown theoretically and numerically that by properly modifying the shunting impedance, the adaptive mechanical mechanism within the tunable resonator can produce high-pass and low-pass wave filtering capabilities for the zeroth-order anti-symmetric Lamb-wave modes. These unique behaviors are due to the hybrid effects from the negative-capacitance and negative-inductance circuit elements. Such a system opens up important perspectives for the development of adaptive vibration or wave-attenuation devices for broadband frequency applications.

  11. Controllability analysis of second-order multi-agent systems with directed and weighted interconnection

    Institute of Scientific and Technical Information of China (English)

    Di GUO; Rong-hao ZHENG; Zhi-yun LIN; Gang-feng YAN

    2015-01-01

    This article investigates the controllability problem of multi-agent systems. Each agent is assumed to be governed by a second-order consensus control law corresponding to a directed and weighted graph. Two types of topology are considered. The fi rst is concerned with directed trees, which represent the class of topology with minimum information exchange among all controllable topologies. A very simple necessary and suffcient condition regarding the weighting scheme is obtained for the controllability of double integrator multi-agent systems in this scenario. The second is concerned with a more general graph that can be reduced to a directed tree by contracting a cluster of nodes to a component. A similar necessary and suffcient condition is derived. Finally, several illustrative examples are provided to demonstrate the theoretical analysis results.

  12. Methanol-induced chain termination in poly(3-hydroxybutyrate) biopolymers: molecular weight control

    Science.gov (United States)

    A systematic study was performed to demonstrate the impact of methanol (MeOH) on poly(3-hydroxybutyrate) (PHB) synthesis and molecular weight (MW) control. Glycerine (init. conc. = 1.0%; w/v), was used as the primary carbon source in batch-culture fermentations with varying concentrations (0 to 0.85...

  13. Influence on and Severity of Weight Concern: Bulimics, Dieters, and Controls.

    Science.gov (United States)

    Jones, Terri L.; Wolchik, Sharlene A.

    Little previous research has compared bulimics to dieters who do not binge eat but who are also concerned with their weight. This study examined differences between college students who were classified as either bulimic (N=21), chronic dieters (N=29), or controls (N=83). The extent to which remarks made by significant others and failure…

  14. Physical Activity, Exercise, and Nutrition Interventions for Weight Control in African American Women

    Science.gov (United States)

    Asare, Matthew; Sharma, Manoj

    2010-01-01

    The purpose of this paper was to review the physical activity, exercise, and nutrition related weight control interventions done with African American women that were published between 2006 and 2010 and suggest ways of enhancing these interventions. A total of 13 studies met the inclusion criteria. The review found significant results with regard…

  15. A weighted mixed-sensitivity H-infinity-control design for irrational transfer matrices

    NARCIS (Netherlands)

    Curtain, RF; Zhou, YS

    1996-01-01

    Approximate solutions to a weighted mixed-sensitivity H-x-control problem for an irrational transfer matrix are obtained by solving the same problem for a reduced-order (rational) transfer matrix. Upper and lower bounds for the sensitivity are obtained in terms of the sensitivity for the reduced-ord

  16. Exercise in pregnant women and birth weight: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Bø Kari

    2011-09-01

    Full Text Available Abstract Background Birth weight plays an important role in infant mortality and morbidity, childhood development, and adult health. To date there are contradictory results regarding the role of physical activity on birth weight. In addition, it is questioned whether exercise during second and third trimesters of pregnancy might affect gestational age and increase the risk of preterm delivery. Hence, the purpose of this study was to examine the effect of a supervised exercise-program on birth weight, gestational age at delivery and Apgar-score. Methods Sedentary, nulliparous pregnant women (N = 105, mean age 30.7 ± 4.0 years, pre-pregnancy BMI 23.8 ± 4.3 were randomized to either an exercise group (EG, n = 52 or a control group (CG, n = 53. The exercise program consisted of supervised aerobic dance and strength training for 60 minutes, twice per week for a minimum of 12 weeks, with an additional 30 minutes of self-imposed physical activity on the non-supervised week-days. Results There was no statistically significant difference between groups in mean birth weight, low birth weight ( Conclusion Aerobic-dance exercise was not associated with reduction in birth weight, preterm birth rate or neonatal well-being. Trial Registration ClinicalTrials.gov: NCT00617149

  17. Combining independent, weighted P-values: achieving computational stability by a systematic expansion with controllable accuracy.

    Directory of Open Access Journals (Sweden)

    Gelio Alves

    Full Text Available Given the expanding availability of scientific data and tools to analyze them, combining different assessments of the same piece of information has become increasingly important for social, biological, and even physical sciences. This task demands, to begin with, a method-independent standard, such as the P-value, that can be used to assess the reliability of a piece of information. Good's formula and Fisher's method combine independent P-values with respectively unequal and equal weights. Both approaches may be regarded as limiting instances of a general case of combining P-values from m groups; P-values within each group are weighted equally, while weight varies by group. When some of the weights become nearly degenerate, as cautioned by Good, numeric instability occurs in computation of the combined P-values. We deal explicitly with this difficulty by deriving a controlled expansion, in powers of differences in inverse weights, that provides both accurate statistics and stable numerics. We illustrate the utility of this systematic approach with a few examples. In addition, we also provide here an alternative derivation for the probability distribution function of the general case and show how the analytic formula obtained reduces to both Good's and Fisher's methods as special cases. A C++ program, which computes the combined P-values with equal numerical stability regardless of whether weights are (nearly degenerate or not, is available for download at our group website http://www.ncbi.nlm.nih.gov/CBBresearch/Yu/downloads/CoinedPValues.html.

  18. Combining independent, weighted P-values: achieving computational stability by a systematic expansion with controllable accuracy.

    Science.gov (United States)

    Alves, Gelio; Yu, Yi-Kuo

    2011-01-01

    Given the expanding availability of scientific data and tools to analyze them, combining different assessments of the same piece of information has become increasingly important for social, biological, and even physical sciences. This task demands, to begin with, a method-independent standard, such as the P-value, that can be used to assess the reliability of a piece of information. Good's formula and Fisher's method combine independent P-values with respectively unequal and equal weights. Both approaches may be regarded as limiting instances of a general case of combining P-values from m groups; P-values within each group are weighted equally, while weight varies by group. When some of the weights become nearly degenerate, as cautioned by Good, numeric instability occurs in computation of the combined P-values. We deal explicitly with this difficulty by deriving a controlled expansion, in powers of differences in inverse weights, that provides both accurate statistics and stable numerics. We illustrate the utility of this systematic approach with a few examples. In addition, we also provide here an alternative derivation for the probability distribution function of the general case and show how the analytic formula obtained reduces to both Good's and Fisher's methods as special cases. A C++ program, which computes the combined P-values with equal numerical stability regardless of whether weights are (nearly) degenerate or not, is available for download at our group website http://www.ncbi.nlm.nih.gov/CBBresearch/Yu/downloads/CoinedPValues.html.

  19. Evaluation of a commercial web-based weight loss and weight loss maintenance program in overweight and obese adults: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Neve Melinda

    2010-11-01

    Full Text Available Abstract Background Obesity rates in adults continue to rise and effective treatment programs with a broad reach are urgently required. This paper describes the study protocol for a web-based randomized controlled trial (RCT of a commercially available program for overweight and obese adult males and females. The aim of this RCT was to determine and compare the efficacy of two web-based interventions for weight loss and maintenance of lost weight. Methods/Design Overweight and obese adult males and females were stratified by gender and BMI and randomly assigned to one of three groups for 12-weeks: waitlist control, or basic or enhanced online weight-loss. Control participants were re-randomized to the two weight loss groups at the end of the 12-week period. The basic and enhanced group participants had an option to continue or repeat the 12-week program. If the weight loss goal was achieved at the end of 12, otherwise on completion of 24 weeks of weight loss, participants were re-randomized to one of two online maintenance programs (maintenance basic or maintenance enhanced, until 18 months from commencing the weight loss program. Assessments took place at baseline, three, six, and 18 months after commencing the initial weight loss intervention with control participants repeating the initial assessment after three month of waiting. The primary outcome is body mass index (BMI. Other outcomes include weight, waist circumference, blood pressure, plasma markers of cardiovascular disease risk, dietary intake, eating behaviours, physical activity and quality of life. Both the weight loss and maintenance of lost weight programs were based on social cognitive theory with participants advised to set goals, self-monitor weight, dietary intake and physical activity levels. The enhanced weight loss and maintenance programs provided additional personalized, system-generated feedback on progress and use of the program. Details of the methodological aspects of

  20. The effects of umbilical cord milking in extremely preterm infants: a randomized controlled trial

    Science.gov (United States)

    March, MI; Hacker, MR; Parson, AW; Modest, AM; de Veciana, M

    2014-01-01

    OBJECTIVE Delayed cord clamping has been shown to decrease the need for transfusion in preterm neonates, but may delay resuscitation. The aim of this study was to determine whether umbilical cord milking compared with immediate cord clamping in extremely preterm deliveries reduces the need for neonatal red blood cell transfusion. STUDY DESIGN Women admitted to a tertiary care center and expected to deliver between 24 to 28 completed weeks of gestation were randomized to cord milking before clamping or immediate cord clamping. The primary outcome was the risk of neonatal transfusion, reported as risk ratio (RR) and 95% confidence interval (CI). RESULT Of 113 women who were enrolled and randomized, 56 were assigned to cord milking with 36 remaining eligible and completing the study and 57 were assigned to the control group with 39 remaining eligible and completing the study. Albeit not statistically significant, neonates in the cord milking group were less likely to require transfusion compared with those in the control group (RR: 0.86; 95% CI: 0.73 to 1.0). Neonates whose cords were milked had higher hematocrits at birth (P = 0.004) and were less likely to develop an intraventricular hemorrhage (P = 0.0195). CONCLUSION Milking the umbilical cord of a preterm neonate is an easy intervention with the potential to improve perinatal outcomes. Our results suggest that milking of the cord increases the neonate’s initial hematocrit and may lessen the need for transfusion in the neonatal period. The observed reduction in the incidence of intraventricular hemorrhage may have important long-term implications that warrant further study. PMID:23867960

  1. Intelligent Control System Taking Account of Cooperativeness Using Weighting Information on System Objective

    Directory of Open Access Journals (Sweden)

    Masaki Takahashi

    2004-08-01

    Full Text Available This study considers an intelligent control system to integrate flexibly its components by using weighted information where the system evaluation is reflected. Such system evaluates the information flowing through the components and converts them by weighting depending on the degree of importance. Integration of components based on the system evaluation enables a system consisting of them to realize various, flexible and adaptive control. In this study, the intelligent control method is applied to a swing up and stabilization control problem of a number of cart and pendulum systems on a restricted straight guide. To stabilize the pendulum in a restricted environment, each system should realize not only a swing-up and stabilization control of the pendulum, but also a position control of the cart to avoid collision or deadlock. The experiment using a real apparatus demonstrated that the controller learning light interaction acquires egoistic character, the controller learning heavy interaction behaves altruistically, and the controller equally considering self cart and another cart becomes cooperative. In other words, these autonomous decentralized controllers can acquire various characters and flexibility for cooperation.

  2. Non-weight-bearing neural control of a powered transfemoral prosthesis.

    Science.gov (United States)

    Hargrove, Levi J; Simon, Ann M; Lipschutz, Robert; Finucane, Suzanne B; Kuiken, Todd A

    2013-06-19

    Lower limb prostheses have traditionally been mechanically passive devices without electronic control systems. Microprocessor-controlled passive and powered devices have recently received much interest from the clinical and research communities. The control systems for these devices typically use finite-state controllers to interpret data measured from mechanical sensors embedded within the prosthesis. In this paper we investigated a control system that relied on information extracted from myoelectric signals to control a lower limb prosthesis while amputee patients were seated. Sagittal plane motions of the knee and ankle can be accurately (>90%) recognized and controlled in both a virtual environment and on an actuated transfemoral prosthesis using only myoelectric signals measured from nine residual thigh muscles. Patients also demonstrated accurate (~90%) control of both the femoral and tibial rotation degrees of freedom within the virtual environment. A channel subset investigation was completed and the results showed that only five residual thigh muscles are required to achieve accurate control. This research is the first step in our long-term goal of implementing myoelectric control of lower limb prostheses during both weight-bearing and non-weight-bearing activities for individuals with transfemoral amputation.

  3. PGC-1α and exercise in the control of body weight.

    Science.gov (United States)

    Summermatter, S; Handschin, C

    2012-11-01

    The increasing prevalence of obesity and its comorbidities represents a major threat to human health globally. Pharmacological treatments exist to achieve weight loss, but the subsequent weight maintenance is prone to fail in the long run. Accordingly, efficient new strategies to persistently control body weight need to be elaborated. Exercise and dietary interventions constitute classical approaches to reduce and maintain body weight, yet people suffering from metabolic diseases are often unwilling or unable to move adequately. The administration of drugs that partially mimic exercise adaptation might circumvent this problem by easing and supporting physical activity. The thermogenic peroxisome proliferator-activated receptor γ coactivator 1α (PGC-1α) largely mediates the adaptive response of skeletal muscle to endurance exercise and is a potential target for such interventions. Here, we review the role of PGC-1α in mediating exercise adaptation, coordinating metabolic circuits and enhancing thermogenic capacity in skeletal muscle. We suggest a combination of elevated muscle PGC-1α and exercise as a modified approach for the efficient long-term control of body weight and the treatment of the metabolic syndrome.

  4. Weight Loss Surgery

    Science.gov (United States)

    Weight loss surgery helps people with extreme obesity to lose weight. It may be an option if you ... caused by obesity. There are different types of weight loss surgery. They often limit the amount of food ...

  5. Bright Light for Weight Loss: Results of a Controlled Crossover Trial

    Directory of Open Access Journals (Sweden)

    Konstantin V. Danilenko

    2013-02-01

    Full Text Available Objective: To investigate whether bright light treatment can reduce body mass in overweight subjects irrespective of their seasonal (= light dependence. Methods: A crossover, placebo-controlled, randomized clinical trial was performed between November and April in Novosibirsk, Russia (55° N. The trial comprised a 3-week in-home session of morning bright light treatment using a device of light-emitting diodes and a 3-week placebo session by means of a deactivated ion generator, separated by an off-protocol period of at least 23 days. The number of placebo and light sessions was matched with respect to season. Data were obtained from 34 overweight women, aged 20-54 years, 10 were seasonal-dependent according to the Seasonal Pattern Assessment Questionnaire. Weekly measures included body weight, percentage body fat by bioimpedancemetry, and subjective scores (appetite, mood, energy levels. Results: Motivation and expectation towards weight loss were similar for the two intervention sessions. With light, compared to the placebo session, weight did not reduce significantly, but percentage fat, fat mass, and appetite were significantly lower (average fat reduction 0.35 kg. The latter two results remained significant after excluding seasonal-dependent subjects from the analysis. Irrespective of the type of intervention, seasonal-dependent subjects had greater weight and fat mass changes during treatment (decline p 0.036 or between sessions (regain p 0.003. Photoperiod (p = 0.0041, air temperature to a lesser extent (p = 0.012, but not sunshine (p = 0.29 was associated with the weight change (greater weight reduction if the second session was in spring. Conclusion: Morning bright light treatment reduces body fat and appetite in overweight women and may be included in weight control programs.

  6. The role of higher protein diets in weight control and obesity-related comorbidities.

    Science.gov (United States)

    Astrup, A; Raben, A; Geiker, N

    2015-05-01

    The importance of the relative dietary content of protein, carbohydrate and the type of carbohydrate (that is, glycemic index (GI)) for weight control under ad libitum conditions has been controversial owing to the lack of large scale studies with high diet adherence. The Diet, Obesity and Genes (DioGenes) European multicentre trial examined the importance of a slight increase in dietary protein content, reduction in carbohydrate and the importance of choosing low (LGI) vs high GI (HGI) carbohydrates for weight control in 932 obese families. Only the adults underwent a diet of 800 kcal per day for 8 weeks, and after losing ~11kg they were randomized to one of five energy ad libitum diets for 6 months. The diets differed in protein content and GI. The high-protein (HP) diet groups consumed 5.4% points more energy from protein than the normal protein (NP) groups, and the LGI diet groups achieved 5.1% lower GI than the HGI groups. The effect of HP and LGI was additive on weight loss and maintenance, and the combination was successful in preventing weight regain and reducing drop-out rate among the adults after the 11kg weight loss. This diet also reduced body fatness and prevalence of overweight and obesity among their children and had consistent beneficial effects on blood pressure, blood lipids and inflammation in both parents and children. After 1 year, mainly the HP effects were maintained. Putative genes have been identified that suggest this diet to be particularly effective in 67% of the population. In conclusion, the DioGenes diet has shown to be effective for prevention of weight regain and for weight reduction in overweight children under ad libitum conditions. The less-restrictive dietary approach fits into a normal food culture, and has been translated into popular diet and cook books in several languages.

  7. A randomized controlled trial testing an Internet delivered cost-benefit approach to weight loss maintenance.

    Science.gov (United States)

    Leahey, Tricia M; Fava, Joseph L; Seiden, Andrew; Fernandes, Denise; Doyle, Caroline; Kent, Kimberly; La Rue, Molly; Mitchell, Marc; Wing, Rena R

    2016-11-01

    Weight loss maintenance is a significant challenge in obesity treatment. During maintenance the "costs" of adhering to weight management behaviors may outweigh the "benefits." This study examined the efficacy of a novel approach to weight loss maintenance based on modifying the cost-benefit ratio. Individuals who achieved a 5% weight loss (N=75) were randomized to one of three, 10-month maintenance interventions. All interventions were delivered primarily via the Internet. The Standard arm received traditional weight maintenance strategies. To increase benefits, or rewards, for maintenance behaviors, the two cost-benefit intervention conditions received weekly monetary rewards for self-monitoring and social reinforcement via e-coaching. To decrease behavioral costs (boredom) and increase novelty, participants in the cost-benefit conditions also monitored different evidence-based behaviors every two weeks (e.g., Weeks 1 & 2: steps; Week 3 & 4: red foods). The primary difference between the cost-benefit interventions was type of e-coach providing social reinforcement: Professional (CB Pro) or Peer (CB Peer). Study procedures took place in Providence, RI from 2013 to 2014. Retention was 99%. There were significant group differences in weight regain (p=.01). The Standard arm gained 3.5±5.7kg. In contrast, participants in CB Pro and CB Peer lost an additional 1.8±7.0kg and 0.5±6.4kg, respectively. These results suggest that an Internet delivered cost-benefit approach to weight loss maintenance may be effective for long-term weight control. In addition, using peer coaches to provide reinforcement may be a particularly economic alternative to professionals. These data are promising and provide support for a larger, longer trial.

  8. Surgical vs conventional therapy for weight loss treatment of obstructive sleep apnea: a randomized controlled trial.

    Science.gov (United States)

    Dixon, John B; Schachter, Linda M; O'Brien, Paul E; Jones, Kay; Grima, Mariee; Lambert, Gavin; Brown, Wendy; Bailey, Michael; Naughton, Matthew T

    2012-09-19

    Obstructive sleep apnea (OSA) is strongly related to obesity. Weight loss is recommended as part of the overall management plan for obese patients diagnosed with OSA. To determine whether surgically induced weight loss is more effective than conventional weight loss therapy in the management of OSA. A randomized controlled trial of 60 obese patients (body mass index: >35 and obesity hypoventilation syndrome, previous bariatric surgery, contraindications to bariatric surgery, or significant cardiopulmonary, neurological, vascular, gastrointestinal, or neoplastic disease were excluded. Patients were randomized to a conventional weight loss program that included regular consultations with a dietitian and physician, and the use of very low-calorie diets as necessary (n = 30) or to bariatric surgery (laparoscopic adjustable gastric banding; n = 30). The primary outcome was baseline to 2-year change in AHI on diagnostic polysomnography scored by staff blinded to randomization. Secondary outcomes were changes in weight, CPAP adherence, and functional status. Patients lost a mean of 5.1 kg (95% CI, 0.8 to 9.3 kg) in the conventional weight loss program compared with 27.8 kg (95% CI, 20.9 to 34.7 kg) in the bariatric surgery group (P adherence did not differ between the groups. The bariatric surgery group had greater improvement in the Short Form 36 physical component summary score (mean, 9.3 [95% CI, 0.5 to 18.0]; P = .04). Among a group of obese patients with OSA, the use of bariatric surgery compared with conventional weight loss therapy did not result in a statistically greater reduction in AHI despite major differences in weight loss. anzctr.org Identifier: 12605000161628.

  9. 超低出生体重儿生存状况分析%Investigation of the extremely low birth weight infant living condition

    Institute of Scientific and Technical Information of China (English)

    陆丹芳; 童笑梅

    2013-01-01

    【Objective】 To investigate the extremely low birth weight infant's (ELBWI) quality of life and related intervention measures through review of ELBWI's living condition from a single centre NICU in recently years. 【Method】 It was retrospectively analyzed about the clinical data of 32 patients of ELBWI from February 2000 to January 2012. 【Results】 The ELBWI suvival rate, mortality rate, abandon rate were 34. 4%, 25. 0%,and 40. 6% respectively. The Assisted Reproductive Technologies (ART) ELBWI suvival rate was 75. 0%. Female suvival rate(72. 7%) was higer than male's in all suvival patients. The common direct causes of death were pulmonary haemorrhage (62. 5%), hyaline membrane disease (12. 5%),intracranial haemorrhage(12. 5%) and gastrointestinal bleeding(12. 5%). The data were divided into two stages (February 2000~January 2006 vs February 2006~January 2012). Compared with the former group,the abandon rate of the later was obviously lower(28. 0% vs 85. 7%) and suvival rate was significantly higher (44% vs 0%). There was significant diffrence of ART between survival group and mortality/abandon group(P<0. 05) with single factor analysis and logistic regression analysis.【Conclusion】 Positive treatment and timely processing of complications can improve ELBWI survival rate and reduce mortality. The treatment of survival limits.ELBWI should weigh up pros and cons,and should elevated the living quality of ELBWI.%[目的] 通过对12年来中心NICU中超低出生体重儿(extremely low birth weight infant,ELBWI)的生存状况分析,探讨ELBWI的生存质量及相关干预措施. [方法]对本院新生儿病房NICU自2000年2月-2012年1月的32例ELBWI进行回顾性分析. [结果]12年来ELBWI存活率34.4%,病死率25.0%,放弃率40.6%,辅助生育的ELBWI均积极治疗,存活率75.0%.所有存活者中女性占72.7%,明显高于男性.直接死亡原因最常见肺出血(62.5%),其次为早产儿肺透明膜病(12.5

  10. [The efficacy of e-health management on weight control in adolescents: a systematic review].

    Science.gov (United States)

    Su, Mei-Chen; Lin, Chia-Ling; Tsao, Lee-Ing

    2014-02-01

    Advances during the past decade have made it feasible to apply e-health methods to chronic disease management. Researchers have recently begun applying these methods to weight control. The application of e-health management methods to weight control in adolescents has yet to be investigated empirically. This study conducted a systematic review of reports discussing the weight-control effects of e-health management in adolescents. Researchers searched 6 electronic databases for relevant articles published between 1995 and April 2013. Data were collected using inclusion and exclusion criteria. A modified Jadad Scale was used to evaluate the quality of the identified articles. Seven studies met the inclusion criterion of targeting adolescent subject populations. A total of 3728 adolescents and 1394 parents participated in these studies. The majority of participants were overweight girls and median participant ages ranged from 12.52 (SD = 3.15) to 15.31 (SD = 0.69). All studies reported that e-health management reduced body mass index and body fat percentage. Four studies indicate that e-health management may improve physical activity knowledge and skills. However, diet control outcomes among the seven studies varied. Empirical results demonstrate that e-health management significantly affects weight control. However, the effectiveness of log-in versus primary outcome indicators was inconclusive. Future studies should consider the use of incentives, reminder systems, and other strategies to enhance website usage. The development of an Internet-based, computer-tailored weight-management intervention for overweight adolescents and the development of an appropriate care model are recommended.

  11. Prevention of unintentional weight loss in nursing home residents: a controlled trial of feeding assistance.

    Science.gov (United States)

    Simmons, Sandra F; Keeler, Emmett; Zhuo, Xiaohui; Hickey, Kelly A; Sato, Hui-Wen; Schnelle, John F

    2008-08-01

    To determine the effects of a feeding assistance intervention on food and fluid intake and body weight. Crossover controlled trial. Four skilled nursing homes (NHs). Seventy-six long-stay NH residents at risk for unintentional weight loss. Research staff provided feeding assistance twice per day during or between meals, 5 days per week for 24 weeks. Research staff independently weighed residents at baseline and monthly during a 24-week intervention and 24-week control period. Residents' food and fluid intake and the amount of staff time spent providing assistance to eat was assessed for 2 days at baseline and 3 and 6 months during each 24-week period. The intervention group showed a significant increase in estimated total daily caloric intake and maintained or gained weight, whereas the control group showed no change in estimated total daily caloric intake and lost weight over 24 weeks. The average amount of staff time required to provide the interventions was 42 minutes per person per meal and 13 minutes per person per between-meal snack, versus usual care, during which residents received, on average, 5 minutes of assistance per person per meal and less than 1 minute per person per snack. Two feeding assistance interventions are efficacious in promoting food and fluid intake and weight gain in residents at risk for weight loss. Both interventions require more staff time than usual NH care. The delivery of snacks between meals requires less time than mealtime assistance and thus may be more practical to implement in daily NH care practice.

  12. Suicidality and unhealthy weight control behaviors among female underaged psychiatric inpatients.

    Science.gov (United States)

    Laakso, Ella; Hakko, Helinä; Räsänen, Pirkko; Riala, Kaisa

    2013-02-01

    The aim of this study was to investigate whether unhealthy weight control behaviors, fear of becoming obese, binge eating, impulsivity, and body mass index are associated with suicide ideation, repetitive self-mutilative behavior (SMB), suicide attempts, or both suicide attempts and SMB among female adolescent psychiatric inpatients. Data were drawn from a clinical inpatient cohort of female adolescents (N = 300, aged 12-17 years) consecutively admitted for psychiatric hospitalization between April 2001 and March 2006. Information on adolescents' suicidal behavior, psychiatric Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), diagnoses and weight control behaviors was obtained using the Schedule for Affective Disorder and Schizophrenia for School-Age Children Present and Lifetime (K-SADS-PL). Even after adjustment with DSM-IV, affective, anxiety and eating disorders self-induced vomiting was significantly associated with SMB and suicide attempts with SMB. Impulsivity was related to suicide attempts with SMB. Excessive exercising was a significant finding only in those girls who had attempted suicide. Girls who had attempted suicide were more often overweight compared with girls without suicidal behavior. Unhealthy weight control behaviors among adolescent girls were found to be strongly associated with suicidal behavior. Girls with a history of both suicide attempts and SMB seem to be the most disturbed group, with multiple weight loss methods and impulsivity. Girls who are overweight or exercise excessively may represent risk groups for attempted suicide. Copyright © 2013 Elsevier Inc. All rights reserved.

  13. Effect of Weight Gain on Cardiac Autonomic Control During Wakefulness and Sleep

    Science.gov (United States)

    Adachi, Taro; Sert-Kuniyoshi, Fatima H.; Calvin, Andrew D.; Singh, Prachi; Romero-Corral, Abel; van der Walt, Christelle; Davison, Diane E.; Bukartyk, Jan; Konecny, Tomas; Pusalavidyasagar, Snigdha; Sierra-Johnson, Justo; Somers, Virend K.

    2012-01-01

    Obesity has been associated with increased cardiac sympathetic activation during wakefulness, but the effect on sleep-related sympathetic modulation is not known. The aim of this study was to investigate the effect of fat gain on cardiac autonomic control during wakefulness and sleep in humans. We performed a randomized controlled study to assess the effects of fat gain on heart rate variability (HRV). We recruited 36 healthy volunteers, who were randomized to either a standardized diet to gain approximately 4 kg over 8 weeks followed by an 8 week weight loss period (n=20), or to serve as a weight-maintainer control (n=16). An overnight polysomnogram with power spectral analysis of HRV was performed at baseline, after weight gain, and after weight loss to determine the ratio of low frequency (LF) to high frequency (HF) power, and to examine the relationship between changes in HRV and changes in insulin, leptin and adiponectin levels. Mean weight gain was 3.9 kg in the fat gain group versus 0.1 kg in the maintainer group. LF/HF increased both during wakefulness and sleep after fat gain and returned to baseline after fat loss in the fat gain group, and did not change in the control group. Insulin, leptin and adiponectin also increased after fat gain and fell after fat loss, but no clear pattern of changes were seen that correlated consistently with changes in HRV. Short-term fat gain in healthy subjects is associated with increased cardiac sympathetic activation during wakefulness and sleep but the mechanisms remain unclear. PMID:21357280

  14. Preventing Weight Gain in Women in Rural Communities: A Cluster Randomised Controlled Trial.

    Directory of Open Access Journals (Sweden)

    Catherine Lombard

    2016-01-01

    Full Text Available Obesity is reaching epidemic proportions in both developed and developing countries. Even modest weight gain increases the risk for chronic illness, yet evidence-based interventions to prevent weight gain are rare. This trial will determine if a simple low-intensity intervention can prevent weight gain in women compared to general health information.We conducted a 1-yr pragmatic, cluster randomised controlled trial in 41 Australian towns (clusters randomised using a computer-generated randomisation list for intervention (n = 21 or control (n = 20. Women aged 18 to 50 yr were recruited from the general population to receive a 1-yr self-management lifestyle intervention (HeLP-her consisting of one group session, monthly SMS text messages, one phone coaching session, and a program manual, or to a control group receiving one general women's health education session. From October 2012 to April 2014 we studied 649 women, mean age 39.6 yr (+/- SD 6.7 and BMI of 28.8 kg/m(2 (+/- SD 6.9 with the primary outcome weight change between groups at 1 yr. The mean change in the control was +0.44 kg (95% CI -0.09 to 0.97 and in the intervention group -0.48 kg (95% CI -0.99 to 0.03 with an unadjusted between group difference of -0.92 kg (95% CI -1.67 to -0.16 or -0.87 kg (95% CI -1.62 to -0.13 adjusted for baseline values and clustering. Secondary outcomes included improved diet quality and greater self-management behaviours. The intervention appeared to be equally efficacious across all age, BMI, income, and education subgroups. Loss to follow-up included 23.8% in the intervention group and 21.8% in the control group and was within the anticipated range. Limitations include lack of sensitive tools to measure the small changes to energy intake and physical activity. Those who gained weight may have been less inclined to return for 1 yr weight measures.A low intensity lifestyle program can prevent the persistent weight gain observed in women. Key features included

  15. Characterization of Extremely Low Frequency Magnetic Fields from Diesel, Gasoline and Hybrid Cars under Controlled Conditions

    Directory of Open Access Journals (Sweden)

    Ronen Hareuveny

    2015-01-01

    Full Text Available This study characterizes extremely low frequency (ELF magnetic field (MF levels in 10 car models. Extensive measurements were conducted in three diesel, four gasoline, and three hybrid cars, under similar controlled conditions and negligible background fields. Averaged over all four seats under various driving scenarios the fields were lowest in diesel cars (0.02 μT, higher for gasoline (0.04–0.05 μT and highest in hybrids (0.06–0.09 μT, but all were in-line with daily exposures from other sources. Hybrid cars had the highest mean and 95th percentile MF levels, and an especially large percentage of measurements above 0.2 μT. These parameters were also higher for moving conditions compared to standing while idling or revving at 2500 RPM and higher still at 80 km/h compared to 40 km/h. Fields in non-hybrid cars were higher at the front seats, while in hybrid cars they were higher at the back seats, particularly the back right seat where 16%–69% of measurements were greater than 0.2 μT. As our results do not include low frequency fields (below 30 Hz that might be generated by tire rotation, we suggest that net currents flowing through the cars’ metallic chassis may be a possible source of MF. Larger surveys in standardized and well-described settings should be conducted with different types of vehicles and with spectral analysis of fields including lower frequencies due to magnetization of tires.

  16. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management.

    Science.gov (United States)

    Pi-Sunyer, Xavier; Astrup, Arne; Fujioka, Ken; Greenway, Frank; Halpern, Alfredo; Krempf, Michel; Lau, David C W; le Roux, Carel W; Violante Ortiz, Rafael; Jensen, Christine Bjørn; Wilding, John P H

    2015-07-02

    Obesity is a chronic disease with serious health consequences, but weight loss is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like peptide-1 analogue, has been shown to have potential benefit for weight management at a once-daily dose of 3.0 mg, injected subcutaneously. We conducted a 56-week, double-blind trial involving 3731 patients who did not have type 2 diabetes and who had a body-mass index (BMI; the weight in kilograms divided by the square of the height in meters) of at least 30 or a BMI of at least 27 if they had treated or untreated dyslipidemia or hypertension. We randomly assigned patients in a 2:1 ratio to receive once-daily subcutaneous injections of liraglutide at a dose of 3.0 mg (2487 patients) or placebo (1244 patients); both groups received counseling on lifestyle modification. The coprimary end points were the change in body weight and the proportions of patients losing at least 5% and more than 10% of their initial body weight. At baseline, the mean (±SD) age of the patients was 45.1±12.0 years, the mean weight was 106.2±21.4 kg, and the mean BMI was 38.3±6.4; a total of 78.5% of the patients were women and 61.2% had prediabetes. At week 56, patients in the liraglutide group had lost a mean of 8.4±7.3 kg of body weight, and those in the placebo group had lost a mean of 2.8±6.5 kg (a difference of -5.6 kg; 95% confidence interval, -6.0 to -5.1; Pweight (Pweight (Pweight and improved metabolic control. (Funded by Novo Nordisk; SCALE Obesity and Prediabetes NN8022-1839 ClinicalTrials.gov number, NCT01272219.).

  17. Measured body mass index, body weight perception, dissatisfaction and control practices in urban, low-income African American adolescents

    Directory of Open Access Journals (Sweden)

    Chen Xiaoli

    2009-06-01

    Full Text Available Abstract Background Current understanding of the associations between actual body weight status, weight perception, body dissatisfaction, and weight control practices among low-income urban African American adolescents is limited. The knowledge can help direct future intervention efforts. Methods Cross-sectional data including measured weight and height and self-reported weight status collected from 448 adolescents in four Chicago Public Schools were used. Results The prevalence of overweight and obesity (BMI ≥ 85th percentile was 39.8%, but only 27.2% considered themselves as obese, although 43.4% reported trying to lose weight. Girls were more likely to express weight dissatisfaction than boys, especially those with BMI ≥ 95th percentile (62.9% vs. 25.9%. BMI ≥ 85th percentile girls were more likely to try to lose weight than boys (84.6% vs. 66.7%. Among all adolescents, 27.2% underestimated and 67.2% correctly judged their own weight status. Multinomial logistic models show that those with BMI ≥ 85th percentile, self-perceived as obese, or expressed body dissatisfaction were more likely to try to lose weight; adjusted odds ratios and 95% confidence intervals were 4.52 (2.53–8.08, 18.04 (7.19–45.30, 4.12 (1.64–10.37, respectively. No significant differences were found in diet and physical activity between those trying to lose weight and those not trying, but boys who reported trying to lose weight still spent more television time (P Conclusion Gender differences in weight perception, body dissatisfaction, and weight control practices exist among African American adolescents. One-third did not appropriately classify their weight status. Weight perception and body dissatisfaction are correlates of weight control practices. Adolescents attempting to lose weight need be empowered to make adequate desirable behavioral changes.

  18. Web-based interventions for weight loss and weight maintenance among rural midlife and older women: protocol for a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Boeckner Linda S

    2011-06-01

    Full Text Available Abstract Background Weight loss is challenging and maintenance of weight loss is problematic among midlife and older rural women. Finding effective interventions using innovative delivery methods that can reach underserved and vulnerable populations of overweight and obese rural women is a public health challenge. Methods/Design This Women Weigh-In for Wellness (The WWW study randomized-controlled trial is designed to compare the effectiveness of theory-based behavior-change interventions using (1 website only, (2 website with peer-led support, or (3 website with professional email-counseling to facilitate initial weight loss (baseline to 6 months, guided continuing weight loss and maintenance (7-18 months and self-directed weight maintenance (19-30 months among rural women ages 45-69 with a BMI of 28-45. Recruitment efforts using local media will target 306 rural women who live within driving distance of a community college site where assessments will be conducted at baseline, 3, 6, 12, 18, 24 and 30 months by research nurses blinded to group assignments. Primary outcomes include changes in body weight, % weight loss, and eating and activity behavioral and biomarkers from baseline to each subsequent assessment. Secondary outcomes will be percentage of women achieving at least 5% and 10% weight loss without regain from baseline to 6, 18, and 30 months and achieving healthy eating and activity targets. Data analysis will use generalized estimating equations to analyze average change across groups and group differences in proportion of participants achieving target weight loss levels. Discussion The Women Weigh-In for Wellness study compares innovative web-based alternatives for providing lifestyle behavior-change interventions for promoting weight loss and weight maintenance among rural women. If effective, such interventions would offer potential for reducing overweight and obesity among a vulnerable, hard-to-reach, population of rural women

  19. Parenchymal texture measures weighted by breast anatomy: preliminary optimization in a case-control study

    Science.gov (United States)

    Gastounioti, Aimilia; Keller, Brad M.; Hsieh, Meng-Kang; Conant, Emily F.; Kontos, Despina

    2016-03-01

    Growing evidence suggests that quantitative descriptors of the parenchymal texture patterns hold a valuable role in assessing an individual woman's risk for breast cancer. In this work, we assess the hypothesis that breast cancer risk factors are not uniformly expressed in the breast parenchymal tissue and, therefore, breast-anatomy-weighted parenchymal texture descriptors, where different breasts ROIs have non uniform contributions, may enhance breast cancer risk assessment. To this end, we introduce an automated breast-anatomy-driven methodology which generates a breast atlas, which is then used to produce a weight map that reinforces the contributions of the central and upper-outer breast areas. We incorporate this methodology to our previously validated lattice-based strategy for parenchymal texture analysis. In the framework of a pilot case-control study, including digital mammograms from 424 women, our proposed breast-anatomy-weighted texture descriptors are optimized and evaluated against non weighted texture features, using regression analysis with leave-one-out cross validation. The classification performance is assessed in terms of the area under the curve (AUC) of the receiver operating characteristic. The collective discriminatory capacity of the weighted texture features was maximized (AUC=0.87) when the central breast area was considered more important than the upperouter area, with significant performance improvement (DeLong's test, p-valuepersonalized recommendations regarding women's cancer risk evaluation.

  20. Weight loss herbal intervention therapy (W-LHIT) a non-appetite suppressing natural product controls weight and lowers cholesterol and glucose levels in a murine model

    OpenAIRE

    Yang, Nan; Chung, Danna; Liu, Changda; Liang, Banghao; Li, Xiu-Min

    2014-01-01

    Background The prevalence of obesity is increasing in industrialized countries. Obesity increases the risk of coronary artery disease, stroke, cancer, hypertension, and type-2 diabetes. Unfortunately, conventional obesity drug treatment is often associated with adverse effects. The objective of this study was to evaluate a novel natural formula, Weight loss herbal intervention therapy (W-LHIT), developed from traditional Chinese medicine, for weight control in a high-fat-diet (HFD) induced ob...

  1. Differences between young and older adults in the control of weight shifting within the surface of support

    NARCIS (Netherlands)

    de Vries, Elisabeth A; Caljouw, Simone R; Coppens, Milou J M; Postema, Klaas; Verkerke, Gijsbertus J; Lamoth, Claudine J C

    2014-01-01

    An important reason for falling in elderly is incorrect weight-shifting. In many daily life activities quick and accurate weight-shifting is needed to maintain balance and to prevent from falling. The present study aims to gain more insight in age-related differences in the control of weight-shiftin

  2. Does This Make Me Look Fat? Peer Crowd and Peer Contributions to Adolescent Girls' Weight Control Behaviors

    Science.gov (United States)

    Mackey, Eleanor Race; La Greca, Annette M.

    2008-01-01

    Based on the Theory of Reasoned Action, this study evaluated a "socialization" model linking girls' peer crowd affiliations (e.g., Jocks, Populars) with their own weight concern, perceived peer weight norms, and weight control behaviors. An alternative "selection" model was also evaluated. Girls (N = 236; M age = 15.95 years) from diverse ethnic…

  3. Vitamin D status and weight loss: a systematic review and meta-analysis of randomized and nonrandomized controlled weight-loss trials.

    Science.gov (United States)

    Mallard, Simonette R; Howe, Anna S; Houghton, Lisa A

    2016-10-01

    Obesity is associated with lower concentrations of serum 25-hydroxyvitamin D; however, uncertainty exists as to the direction of causation. To date, meta-analyses of randomized controlled vitamin D-supplementation trials have shown no effect of raising circulating vitamin D on body weight, although several weight-loss-intervention trials have reported an increase in circulating vitamin D after weight reduction. We undertook a systematic review and meta-analysis of randomized and nonrandomized controlled trials to determine whether weight loss compared with weight maintenance leads to an increase in serum 25-hydroxyvitamin D. A systematic search for controlled weight-loss-intervention studies published up to 31 March 2016 was performed. Studies that included participants of any age with changes in adiposity and serum 25-hydroxyvitamin D as primary or secondary outcomes were considered eligible. We identified 4 randomized controlled trials (n = 2554) and 11 nonrandomized controlled trials (n = 917) for inclusion in the meta-analysis. Random assignment to weight loss compared with weight maintenance resulted in a greater increase in serum 25-hydroxyvitamin D with a mean difference of 3.11 nmol/L (95% CI: 1.38, 4.84 nmol/L) between groups, whereas a mean difference of 4.85 nmol/L (95% CI: 2.59, 7.12 nmol/L) was observed in nonrandomized trials. No evidence for a dose-response effect of weight loss on the change in serum 25-hydroxyvitamin D was shown overall. Our results indicate that vitamin D status may be marginally improved with weight loss in comparison with weight maintenance under similar conditions of supplemental vitamin D intake. Although additional studies in unsupplemented individuals are needed to confirm these findings, our results support the view that the association between obesity and lower serum 25-hydroxyvitamin D may be due to reversed causation with increased adiposity leading to suboptimal concentrations of circulating vitamin D. This trial was

  4. Effects of a weight management program delivered by social media on weight and metabolic syndrome risk factors in overweight and obese adults: A randomised controlled trial.

    Science.gov (United States)

    Jane, Monica; Hagger, Martin; Foster, Jonathan; Ho, Suleen; Kane, Robert; Pal, Sebely

    2017-01-01

    The aim of this project was to evaluate the effectiveness of using social media to augment the delivery of, and provide support for, a weight management program delivered to overweight and obese individuals during a twenty four week intervention. Participants randomly divided into either one of two intervention groups or a control group. The two intervention groups were instructed to follow identical weight-management program. One group received the program within a Facebook group, along with a support network with the group, and the other intervention group received the same program in a booklet. The control group was given standard care. Participants' weight and other metabolic syndrome risk factors were measured at baseline and at weeks 6, 12, 18 and 24. The Facebook Group reported a 4.8% reduction in initial weight, significant compared to the CG only (p = 0.01), as well as numerically greater improvements in body mass index, waist circumference, fat mass, lean mass, and energy intake compared to the Pamphlet Group and the Control Group. These results demonstrate the potential of social media to assist overweight and obese individuals with respect to dietary and physical activity modifications for weight management, and justify further research into the inclusion of social media in clinical weight management programs. It is anticipated that social media will provide an invaluable resource for health professionals, as a low maintenance vehicle for communicating with patients, as well as a source of social support and information sharing for individuals undergoing lifestyle modifications.

  5. Voluntary Fasting to Control Post-Ramadan Weight Gain among Overweight and Obese Women

    Directory of Open Access Journals (Sweden)

    Suriani Ismail

    2015-01-01

    Full Text Available Objectives: This study aimed to examine the effectiveness of an Islamic voluntary fasting intervention to control post-Ramadan weight gain. Methods: This study was conducted between July and November 2011. Two weight loss intervention programmes were developed and implemented among groups of overweight or obese Malay women living in the Malaysian cities of Putrajaya and Seremban: a standard programme promoting control of food intake according to national dietary guidelines (group B and a faith-based programme promoting voluntary fasting in addition to the standard programme (group A. Participants’ dietary practices (i.e., voluntary fasting practices, frequency of fruit/vegetable consumption per week and quantity of carbohydrates/protein consumed per day, body mass index (BMI, blood pressure, fasting blood high-density lipoprotein cholesterol (HDL-C and total cholesterol (TC:HDL-C ratio were assessed before Ramadan and three months post-Ramadan. Results: Voluntary fasting practices increased only in group A (P <0.01. Additionally, the quantity of protein/carbohydrates consumed per day, mean diastolic pressure and TC:HDL-C ratio decreased only in group A (P <0.01, 0.05, 0.02 and <0.01, respectively. Frequency of fruit/vegetable consumption per week, as well as HDL-C levels, increased only in group A (P = 0.03 and <0.01, respectively. Although changes in BMI between the groups was not significant (P = 0.08, BMI decrease among participants in group A was significant (P <0.01. Conclusion: Control of post-Ramadan weight gain was more evident in the faith-based intervention group. Healthcare providers should consider faith-based interventions to encourage weight loss during Ramadan and to prevent post-Ramadan weight gain among patients.

  6. Bariatric Surgery in Obese Patients with Type 1 Diabetes: Effects on Weight Loss and Metabolic Control.

    Science.gov (United States)

    Faucher, Pauline; Poitou, Christine; Carette, Claire; Tezenas du Montcel, Sophie; Barsamian, Charles; Touati, Eliabelle; Bouillot, Jean-Luc; Torcivia, Adriana; Czernichow, Sébastien; Oppert, Jean-Michel; Ciangura, Cécile

    2016-10-01

    Type 1 diabetes patients, although typically lean, experience an increased prevalence of obesity, and bariatric surgery is considered in severe cases. Bariatric surgery in such patients leads to significant weight loss and decreased insulin requirements; however, effects on glycemic control remain discussed. We assessed, in obese patients with type 1 diabetes, the effects of bariatric surgery upon body weight, body composition, and glycemic control, including the occurrence of hypoglycemic events. Thirteen obese patients with type 1 diabetes who underwent bariatric surgery (Roux-en-Y gastric bypass n = 6, sleeve gastrectomy n = 7) were matched with obese patients without diabetes and with type 2 diabetes patients during 12 months of follow-up. Outcomes included body weight, DXA-assessed body composition, HbA1c, and incidence of hypoglycemia. At 12 months, median surgery-induced weight loss was 27.9 % (21.1-33.3), 26.1 % (24.8-29.7), and 27.5 % (21.8-32.1) in patients with type 1 diabetes, type 2 diabetes, and without diabetes, respectively, with no significant differences across the groups. Similar findings were observed for body fat changes. At 12 months, median HbA1c decreased from 8.3 to 7.6 % in type 1 diabetes patients versus 8.0 to 5.9 % in type 2 diabetes patients (P = 0.04 between the groups). In type 1 diabetes patients, the number of reported minor hypoglycemia increased transiently only at 6 months. Two patients reported severe hypoglycemia (one episode each). Type 1 diabetes patients benefit from bariatric surgery in terms of weight loss and glycemic control. Close monitoring of insulin therapy appears warranted to prevent minor hypoglycemia in the first months post-surgery.

  7. Reducing Postpartum Weight Retention and Improving Breastfeeding Outcomes in Overweight Women: A Pilot Randomised Controlled Trial

    Directory of Open Access Journals (Sweden)

    Julia Martin

    2015-02-01

    Full Text Available Overweight and obesity is prevalent among women of reproductive age (42% BMI > 25 kg/m2 and parity is associated with risk of weight gain. Weight gain greater than that recommended by the Institute of Medicine (IOM is also associated with lower rates of breastfeeding initiation and duration in women. The aim of this pilot randomised controlled trial is to examine the feasibility of recruiting and maintaining a cohort of pregnant women with the view of reducing postpartum weight retention and improving breastfeeding outcomes. Women (BMI of 25–35 kg/m2 (n = 36 were recruited from the John Hunter Hospital antenatal clinic in New South Wales, Australia. Participants were stratified by BMI and randomised to one of three groups with follow-up to six months postpartum. Women received a dietary intervention with or without breastfeeding support from a lactation consultant, or were assigned to a wait-list control group where the dietary intervention was issued at three months postpartum. Feasibility and acceptability was assessed by participation rates and questionnaire. Analysis of variance and covariance was conducted to determine any differences between groups. Sixty-nine per cent of the participants were still enrolled at six months postpartum. This pilot demonstrated some difficulties in recruiting women from antenatal clinics and retaining them in the trial. Although underpowered; the results on weight; biomarkers and breastfeeding outcomes indicated improved metabolic health.

  8. Effect of olive oil massage on weight gain in preterm infants: A randomized controlled clinical trial

    Directory of Open Access Journals (Sweden)

    Mahnaz Jabraeile

    2016-01-01

    Full Text Available Background: Despite the fact that effect of massage with or without oil on the baby′s weight gain is not clear, but recent studies have shown that massage with essential oils make lipid absorption through the skin. The aim of this study was to evaluate the effect of olive oil massage on weight gain in preterm infants. Materials and Methods: This study was a single-blind, randomized controlled clinical trial. In this study, infants who met inclusion criteria for the study were divided into two groups by using random numbers table. Newborns in intervention group were under massage for 10 days and 3 times for 15 min daily; the mother of these newborns had been trained already using olive oil. Moreover, the infants of the control group were under massaging without oil same as the above-mentioned method. Researchers weighed babies daily during 10 days and recorded it at the checklist. Data from the study were reviewed and analyzed by descriptive statistics and repeated measure test using the statistical software SPSS/13. Results: This study showed that the neonatal weight gain in the infants with the oil massage was 21 g daily in average, whereas the increase in infant massage without oil was 7 g. This difference was statistically significant (P < 0.001. Conclusion: Considering the positive effect of infant massage on weight gain in premature infants with olive oil, it is recommended that nurses use oil in infant massage in the neonatal units.

  9. Efficacy of a meal replacement diet plan compared to a food-based diet plan after a period of weight loss and weight maintenance: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Hutchisen Tammy

    2010-03-01

    Full Text Available Abstract Background Obesity has reached epidemic proportions in the United States. It is implicated in the development of a variety of chronic disease states and is associated with increased levels of inflammation and oxidative stress. The objective of this study is to examine the effect of Medifast's meal replacement program (MD on body weight, body composition, and biomarkers of inflammation and oxidative stress among obese individuals following a period of weight loss and weight maintenance compared to a an isocaloric, food-based diet (FB. Methods This 40-week randomized, controlled clinical trial included 90 obese adults with a body mass index (BMI between 30 and 50 kg/m2, randomly assigned to one of two weight loss programs for 16 weeks and then followed for a 24-week period of weight maintenance. The dietary interventions consisted of Medifast's meal replacement program for weight loss and weight maintenance, or a self-selected, isocaloric, food-based meal plan. Results Weight loss at 16 weeks was significantly better in the Medifast group (MD versus the food-based group (FB (12.3% vs. 6.9%, and while significantly more weight was regained during weight maintenance on MD versus FB, overall greater weight loss was achieved on MD versus FB. Significantly more of the MD participants lost ≥ 5% of their initial weight at week 16 (93% vs. 55% and week 40 (62% vs. 30%. There was no difference in satiety observed between the two groups during the weight loss phase. Significant improvements in body composition were also observed in MD participants compared to FB at week 16 and week 40. At week 40, both groups experienced improvements in biochemical outcomes and other clinical indicators. Conclusions Our data suggest that the meal replacement diet plan evaluated was an effective strategy for producing robust initial weight loss and for achieving improvements in a number of health-related parameters during weight maintenance, including inflammation

  10. MULTI-OBJECTIVE PID CONTROLLER BASED ON ADAPTIVE WEIGHTED PSO WITH APPLICATION TO STEAM TEMPERATURE CONTROL IN BOILERS

    Directory of Open Access Journals (Sweden)

    C.Agees Kumar

    2010-07-01

    Full Text Available PID controller is widely used for main steam temperature control of boiler unit in thermal power plant. To avoid the drawback of current PID design methods, this paper presents a new design method for multi-objective PID controller to synthetically consider system requirement in reliability and robustness. Adaptive weighted PSO (AWPSO technique is applied to the parameter optimization design. The optimization problem considered is highly nonlinear, complex, with multiple objectives and constraints. The simulation results on an actual main steam temperature control system indicate that, the multi-objective PID controller designed by presented method, can improve the dynamic performance of main steam temperature control system, with good robustness ability.

  11. Importância dos minerais na alimentação do pré-termo extremo Minerals in the nutrition of extremely low birth weight infants

    Directory of Open Access Journals (Sweden)

    Cleide E. P. Trindade

    2005-03-01

    Full Text Available OBJETIVO: Revisão crítica da literatura sobre os minerais cálcio, fósforo e microelementos na nutrição do pré-termo extremo, considerando a importância no crescimento, mineralização óssea e como componente de dietas. FONTES DOS DADOS: Utilizamos o banco de dados MEDLINE e o Cochrane Database of Systematic Reviews, de 1994 a 2004. Selecionamos artigos com enfoques originais, artigos de revisão e livros específicos. SÍNTESE DOS DADOS: As dificuldades na nutrição de prematuros extremos aumentam a freqüência de prematuros com restrição de crescimento, cujas conseqüências futuras estão para serem determinadas. Todavia, há pouca literatura sobre minerais, especialmente sobre micronutrientes na nutrição do pré-termo extremo, considerando-se o deficiente armazenamento e a importância destes em nutrição. O principal enfoque desta revisão foi sobre o cálcio e o fósforo na mineralização óssea e na suplementação em nutrição parenteral e enteral, bem como a avaliação crítica da nutrição pós-alta sobre a mineralização óssea. São abordadas as necessidades de micronutrientes, principalmente selênio e zinco, e a função antioxidante do selênio na provável prevenção de doenças do prematuro com atuação de radicais livres. CONCLUSÃO: Considerando os baixos estoques de minerais em prematuros extremos, há necessidade de mais pesquisas sobre minerais na nutrição destes prematuros para definir suas reais necessidades, os aspectos metabólicos, bem como aplicar os conhecimentos na formulação de dietas que permitam prevenir quadros de deficiência e conseqüências a longo prazo. Ainda há controvérsias sobre a influência de fórmulas pós-alta sobre a evolução da doença óssea da prematuridade.OBJECTIVE: To review the literature on the role of calcium, phosphorus and trace elements in the nutrition of extremely low birth weight infants, considering their importance for metabolism, bone mineralization

  12. The role of higher protein diets in weight control and obesity-related comorbidities

    OpenAIRE

    Astrup, A; Raben, A; Geiker, N

    2015-01-01

    The importance of the relative dietary content of protein, carbohydrate and the type of carbohydrate (that is, glycemic index (GI)) for weight control under ad libitum conditions has been controversial owing to the lack of large scale studies with high diet adherence. The Diet, Obesity and Genes (DioGenes) European multicentre trial examined the importance of a slight increase in dietary protein content, reduction in carbohydrate and the importance of choosing low (LGI) vs high GI (HGI) carbo...

  13. Frequency-weighted feedforward control for dynamic compensation in ionic polymer-metal composite actuators

    Science.gov (United States)

    Shan, Yingfeng; Leang, Kam K.

    2009-12-01

    Ionic polymer-metal composites (IPMCs) are innovative materials that offer combined sensing and actuating ability in lightweight and flexible package. IPMCs have been exploited in robotics and a wide variety of biomedical devices, for example, as sensors for teleoperation, as actuators for positioning in active endoscopy, as fins for propelling aquatic robots, and as an injector for drug delivery. In the actuation mode, one of the main challenges is precise position control. In particular, IPMC actuators exhibit relaxation behavior and nonlinearities; and at relatively high operating frequencies dynamic effects limit accuracy and positioning bandwidth. A frequency-weighted feedforward controller is designed to account for the IPMC's structural dynamics to enable fast positioning. The control method is applied to a custom-made Nafion-based IPMC actuator. The controller takes into account the magnitude of the control input to avoid generating excessively large voltages which can damage the IPMC actuator. To account for unmodeled effects not captured by the dynamics model, a feedback controller is integrated with the feedforward controller. Experimental results show a significant improvement in the tracking performance when feedforward control is used. For instance, the feedforward controller shows over 75% reduction in the tracking error compared to the case without feedforward compensation. Finally, the integrated feedforward and feedback control system reduces the tracking error to less than 10% for tracking an 18-Hz triangle-like trajectory. Some of the advantages of feedforward control as well as its limitations are also discussed.

  14. Channel response to extreme floods: Insights on controlling factors from six mountain rivers in northern Apennines, Italy

    Science.gov (United States)

    Surian, Nicola; Righini, Margherita; Lucía, Ana; Nardi, Laura; Amponsah, William; Benvenuti, Marco; Borga, Marco; Cavalli, Marco; Comiti, Francesco; Marchi, Lorenzo; Rinaldi, Massimo; Viero, Alessia

    2016-11-01

    This work addresses the geomorphic response of mountain rivers to extreme floods, exploring the relationships between morphological changes and controlling factors. The research was conducted on six tributaries of the Magra River (northern Apennines, Italy) whose catchments were affected by an extreme flood (estimated recurrence interval > 100 years in most of the basins) on 25 October 2011. An integrated approach was deployed to study this flood, including (i) analysis of channel width changes by comparing aerial photographs taken before and after the flood, (ii) estimate of peak discharges in ungauged streams, (iii) detailed mapping of landslides and analysis of their connectivity with the channel network. Channel widening occurred in 35 reaches out of 39. In reaches with channel slope hydraulic variables alone are not sufficient to satisfactorily explain the channel response to extreme floods, and inclusion of other factors such as lateral confinement is needed to increase explanatory capability of regression models. Concerning hydraulic variables, this study showed that the degree of channel widening is more strongly related to unit stream power calculated based on pre-flood channel width than to cross-sectional stream power and to unit stream power calculated with post-flood channel width. This could suggest that most width changes occurred after the flood peak. Finally, in terms of hazard, it is crucial to document the type and magnitude of channel changes, to identify controlling factors, and most importantly, to develop tools enabling us to predict where major geomorphic changes occur during an extreme flood.

  15. Psychosocial Factors of Different Health Behaviour Patterns in Adolescents: Association with Overweight and Weight Control Behaviours

    Science.gov (United States)

    Veloso, Susana M.; Matos, Margarida G.; Carvalho, Marina; Diniz, José A.

    2012-01-01

    Physical activity, nutrition, and sedentary behaviour combine to influence the risk of overweight among adolescents. This paper aims to identify psychosocial factors of different health behaviour patterns in adolescents and its association with overweight and weight control behaviours. The 3069 adolescents of both genders (average of 14.8 years old) from the 2010 Portuguese survey of Health Behaviour School-Aged Children (HBSC) answered the 2010 HBSC self-reported questionnaire. It used the cluster k-means (nonhierarchy method), qui-square, one-way ANOVA, and logistic regression. Three clusters with different behavioural patterns (physical activity, sedentary, and eating) composed the results obtained. The sedentary group (34%) had lower self-regulation, body satisfaction, health and wellness, family and classmates relationships, communication with the father than the other two groups. The active gamers (25%) had a smaller BMI but used more unhealthy weight control strategies than the other two groups. The healthy group (41%) was more motivated and more satisfied with school but was not different than the active gamers in most psychosocial variables. Differences were found between clusters for weight control behaviours and psychosocial variables. Different strategies for different patterns were necessary in order to promote obesity prevention and, simultaneously, target healthy lifestyle and wellbeing in adolescents. PMID:22811890

  16. Psychosocial Factors of Different Health Behaviour Patterns in Adolescents: Association with Overweight and Weight Control Behaviours

    Directory of Open Access Journals (Sweden)

    Susana M. Veloso

    2012-01-01

    Full Text Available Physical activity, nutrition, and sedentary behaviour combine to influence the risk of overweight among adolescents. This paper aims to identify psychosocial factors of different health behaviour patterns in adolescents and its association with overweight and weight control behaviours. The 3069 adolescents of both genders (average of 14.8 years old from the 2010 Portuguese survey of Health Behaviour School-Aged Children (HBSC answered the 2010 HBSC self-reported questionnaire. It used the cluster k-means (nonhierarchy method, qui-square, one-way ANOVA, and logistic regression. Three clusters with different behavioural patterns (physical activity, sedentary, and eating composed the results obtained. The sedentary group (34% had lower self-regulation, body satisfaction, health and wellness, family and classmates relationships, communication with the father than the other two groups. The active gamers (25% had a smaller BMI but used more unhealthy weight control strategies than the other two groups. The healthy group (41% was more motivated and more satisfied with school but was not different than the active gamers in most psychosocial variables. Differences were found between clusters for weight control behaviours and psychosocial variables. Different strategies for different patterns were necessary in order to promote obesity prevention and, simultaneously, target healthy lifestyle and wellbeing in adolescents.

  17. Effect of educational training on nutrition and weight control in under-18 Spanish wrestlers

    Directory of Open Access Journals (Sweden)

    Andrea Visiedo

    Full Text Available Abstract The aim of this study was to investigate the effect of a formative program concerning nutrition, weight control, and its risks wrestlers under the age of 18 (under-18 at the Spanish national level. The sample comprised 36 under-18 wrestlers that were pre-selected for the Spanish national team. A quasi-experimental design with a pre-test and post-test was used. The dependent variableswere the knowledge of nutrition and weight control and its risks. The independent variable was the educational program. The program had three 30-minute sessions that combined talks, videos, and tasks to complete. Descriptive and inferential analyses were done (t-test, Wilcoxon test. Results indicate that the educational program was effective at increasing under-18 wrestlers’ knowledge about weight control and its risks,but was ineffective with regard to nutrition knowledge. The paper concludes with a discussion regarding the effect of the intervention program, the difficulties with including this type of knowledge and skill in the preparation of combat sport athletes, and the need for further research in this area.

  18. The Power of the Virtual Ideal Self in Weight Control: Weight-Reduced Avatars Can Enhance the Tendency to Delay Gratification and Regulate Dietary Practices.

    Science.gov (United States)

    Kuo, Hsu-Chan; Lee, Chun-Chia; Chiou, Wen-Bin

    2016-02-01

    The tendency to discount larger future benefits in favor of smaller immediate gains (i.e., temporal discounting) is relevant to the issue of obesity. Successful weight loss requires individuals to sacrifice immediate culinary pleasures in favor of future health gains. Based on the notion that increasing the vividness of one's future self may mitigate temporal discounting and promote the ability to delay gratification, we examined whether viewing one's weight-reduced self (i.e., the ideal self) in a virtual environment can decrease temporal discounting and lead to better regulation of dietary practices. Seventy-six undergraduates who had reported an intention to lose weight were recruited to participate in a laboratory experiment and were randomly assigned to interact with either the weight-reduced self (experimental condition) or the present self (control condition) by looking into a dressing mirror in a virtual fitting room. A temporal-discounting task and a taste test were subsequently administered. Results showed that, compared with control participants, participants who viewed their weight-reduced avatars ate less ice cream in a taste test and were more likely to choose a sugar-free drink as a reward. The discounting rate mediated the association between the avatar manipulation and the amount of ice cream eaten in the subsequent taste test. Overall, our findings suggest that a computer-generated image of one's weight-reduced self may assist in resisting impulses that promote immediate gratification over delayed benefits. This research provides a new approach for controlling impulsive behavior such as dietary regulation and weight control.

  19. Real-time simultaneous myoelectric control by transradial amputees using linear and probability-weighted regression.

    Science.gov (United States)

    Smith, Lauren H; Kuiken, Todd A; Hargrove, Levi J

    2015-08-01

    Regression-based prosthesis control using surface electromyography (EMG) has demonstrated real-time simultaneous control of multiple degrees of freedom (DOFs) in transradial amputees. However, these systems have been limited to control of wrist DOFs. Use of intramuscular EMG has shown promise for both wrist and hand control in able-bodied subjects, but to date has not been evaluated in amputee subjects. The objective of this study was to evaluate two regression-based simultaneous control methods using intramuscular EMG in transradial amputees and compare their performance to able-bodied subjects. Two transradial amputees and sixteen able-bodied subjects used fine wire EMG recorded from six forearm muscles to control three wrist/hand DOFs: wrist rotation, wrist flexion/extension, and hand open/close. Both linear regression and probability-weighted regression systems were evaluated in a virtual Fitts' Law test. Though both amputee subjects initially produced worse performance metrics than the able-bodied subjects, the amputee subject who completed multiple experimental blocks of the Fitts' law task demonstrated substantial learning. This subject's performance was within the range of able-bodied subjects by the end of the experiment. Both amputee subjects also showed improved performance when using probability-weighted regression for targets requiring use of only one DOF, and mirrored statistically significant differences observed with able-bodied subjects. These results indicate that amputee subjects may require more learning to achieve similar performance metrics as able-bodied subjects. These results also demonstrate that comparative findings between linear and probability-weighted regression with able-bodied subjects reflect performance differences when used by the amputee population.

  20. Weight-Perception-Based Novel Control of a Power-Assist Robot for the Cooperative Lifting of Light-Weight Objects

    Directory of Open Access Journals (Sweden)

    S. M. Mizanoor Rahman

    2012-10-01

    Full Text Available We developed a 1‐DOF power assist robot system for lifting objects by two humans cooperatively. We hypothesized that weight perception due to inertia might be different from that due to gravity when lifting an object with power‐assist because the perceived weight differs from the actual weight. The system was simulated and two humans cooperatively lifted objects with it. We analyzed human features such as weight perception, load forces, motions etc. We found that the robot reduced the perceived weights to 25% of the actual weights, and the load forces were 8 times larger than the actual requirements. The excessive load forces resulted in excessive accelerations that jeopardized the performances. We then implemented a novel control based on the human features, which was such that a virtual mass exponentially declined from a large value to a small one when subjects lifted objects with the robot and the command velocity exceeded a threshold. The novel control reduced excessive load forces and accelerations and thus enhanced performances in terms of maneuverability, safety etc. The findings may be used to develop power assist robots for manipulating heavy objects in industries that may augment human’s abilities and skills and may improve interactions between robots and users.

  1. Surrounding rock deformation regularity of roadway under extremely complicated geological conditions in deep mine and its control

    Institute of Scientific and Technical Information of China (English)

    刘长友; 何卓军; 万志军

    2003-01-01

    By combining the practices of deep mine mining in Changguang Mine field and using the Universal Distinct Element Code 3.0(UDEC3.0) numerical computing method, the distribution characteristics of deformation field and stress field as well as the surrounding rock deformation regularity of soft rock roadway are analyzed under extremely complicated geological conditions, a technical principle of bolting to control the surrounding rock of roadway is put forward. And also using a dynamic control for surrounding rocks designing method, the supporting parameters and implement plan are rationally determined. The experimental tests have obtained a good controlling result of surrounding rock.

  2. Determinants of rapid weight gain during infancy: baseline results from the NOURISH randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Mihrshahi Seema

    2011-11-01

    Full Text Available Abstract Background Rapid weight gain in infancy is an important predictor of obesity in later childhood. Our aim was to determine which modifiable variables are associated with rapid weight gain in early life. Methods Subjects were healthy infants enrolled in NOURISH, a randomised, controlled trial evaluating an intervention to promote positive early feeding practices. This analysis used the birth and baseline data for NOURISH. Birthweight was collected from hospital records and infants were also weighed at baseline assessment when they were aged 4-7 months and before randomisation. Infant feeding practices and demographic variables were collected from the mother using a self administered questionnaire. Rapid weight gain was defined as an increase in weight-for-age Z-score (using WHO standards above 0.67 SD from birth to baseline assessment, which is interpreted clinically as crossing centile lines on a growth chart. Variables associated with rapid weight gain were evaluated using a multivariable logistic regression model. Results Complete data were available for 612 infants (88% of the total sample recruited with a mean (SD age of 4.3 (1.0 months at baseline assessment. After adjusting for mother's age, smoking in pregnancy, BMI, and education and infant birthweight, age, gender and introduction of solid foods, the only two modifiable factors associated with rapid weight gain to attain statistical significance were formula feeding [OR = 1.72 (95%CI 1.01-2.94, P = 0.047] and feeding on schedule [OR = 2.29 (95%CI 1.14-4.61, P = 0.020]. Male gender and lower birthweight were non-modifiable factors associated with rapid weight gain. Conclusions This analysis supports the contention that there is an association between formula feeding, feeding to schedule and weight gain in the first months of life. Mechanisms may include the actual content of formula milk (e.g. higher protein intake or differences in feeding styles, such as feeding to schedule

  3. How extreme are extremes?

    Science.gov (United States)

    Cucchi, Marco; Petitta, Marcello; Calmanti, Sandro

    2016-04-01

    High temperatures have an impact on the energy balance of any living organism and on the operational capabilities of critical infrastructures. Heat-wave indicators have been mainly developed with the aim of capturing the potential impacts on specific sectors (agriculture, health, wildfires, transport, power generation and distribution). However, the ability to capture the occurrence of extreme temperature events is an essential property of a multi-hazard extreme climate indicator. Aim of this study is to develop a standardized heat-wave indicator, that can be combined with other indices in order to describe multiple hazards in a single indicator. The proposed approach can be used in order to have a quantified indicator of the strenght of a certain extreme. As a matter of fact, extremes are usually distributed in exponential or exponential-exponential functions and it is difficult to quickly asses how strong was an extreme events considering only its magnitude. The proposed approach simplify the quantitative and qualitative communication of extreme magnitude

  4. Collateral Weight Loss in Children Living with Adult Bariatric Surgery Patients: A Case Control Study

    Science.gov (United States)

    Hirsch, Annemarie G.; Wood, G. Craig; Bailey-Davis, Lisa; Lent, Michelle R.; Gerhard, Glenn S.; Still, Christopher D.

    2014-01-01

    Objective To evaluate the impact of adult bariatric surgery on the Body Mass Index (BMI) of children living in the same household. Design and Methods A retrospective case-control study. Case dyads (n=128) were composed of one adult who had bariatric surgery and one child at the same address. Control dyads (n=384) were composed of an adult with obesity but no bariatric surgery and a child at the same address. We used a two-sample t-test to determine whether the differences between actual and expected BMI at follow-up (post-surgery) differed between children in the case and control dyads. Results Among boys who were overweight, boys who lived with a surgery patient had a lower than expected BMI post-surgery, while boys who did not live with a surgery patient had a higher than expected BMI at follow-up (p=0.045). Differences between actual and expected BMIs of children were not significantly different between cases and controls in girls or in children in other weight classes. Conclusions Overweight boys who lived with an adult bariatric surgery patient had a lower than expected BMI after surgery as compared to controls. Future studies may be warranted to determine the mechanisms by which these children experience collateral weight loss. PMID:24989939

  5. Loss to follow-up in a randomized controlled trial study for pediatric weight management (EPOC).

    Science.gov (United States)

    Warschburger, Petra; Kröller, Katja

    2016-11-14

    Attrition is a serious problem in intervention studies. The current study analyzed the attrition rate during follow-up in a randomized controlled pediatric weight management program (EPOC study) within a tertiary care setting. Five hundred twenty-three parents and their 7-13-year-old children with obesity participated in the randomized controlled intervention trial. Follow-up data were assessed 6 and 12 months after the end of treatment. Attrition was defined as providing no objective weight data. Demographic and psychological baseline characteristics were used to predict attrition at 6- and 12-month follow-up using multivariate logistic regression analyses. Objective weight data were available for 49.6 (67.0) % of the children 6 (12) months after the end of treatment. Completers and non-completers at the 6- and 12-month follow-up differed in the amount of weight loss during their inpatient stay, their initial BMI-SDS, educational level of the parents, and child's quality of life and well-being. Additionally, completers supported their child more than non-completers, and at the 12-month follow-up, families with a more structured eating environment were less likely to drop out. On a multivariate level, only educational background and structure of the eating environment remained significant. The minor differences between the completers and the non-completers suggest that our retention strategies were successful. Further research should focus on prevention of attrition in families with a lower educational background. Current Controlled Trials ISRCTN24655766 . Registered 06 September 2008, updated 16 May 2012.

  6. Predictors of initiation and persistence of unhealthy weight control behaviours in adolescents

    Directory of Open Access Journals (Sweden)

    Haines Jess

    2009-10-01

    Full Text Available Abstract Background Unhealthy weight control behaviours (UWCB among adolescents have significant health and weight consequences. The current longitudinal study aimed to identify personal and socio-environmental predictors of initiation or persistence of adolescent UWCB, in order to inform development of programs aimed at both preventing and stopping UWCB. Methods A diverse sample included 1106 boys and 1362 girls from 31 middle schools and high schools in the United States who were enrolled in Project EAT (Eating Among Teens. Project EAT explored personal, behavioural, and socio-environmental factors associated with dietary intake and body weight in adolescence. Participants completed questionnaires to assess demographics, UWCB (including several methods of food restriction, purging by vomiting or medications, smoking to control weight, or food substitutions and personal and socio-environmental variables at two time points, five years apart, between 1998 and 2004. Logistic regression models examined personal and socio-environmental predictors of initiation and persistence of UWCB among Project EAT participants. Results Results indicate that 15.5% of boys and 19.7% of girls initiated UWCB by Time 2, and 15.9% of boys and 43.3% of girls persisted with these behaviours from Time 1 to Time 2. After controlling for race/ethnicity and weight status changes between assessments, logistic regression models indicated that similar factors and patterns of factors were associated significantly with initiation and persistence of UWCB. For both boys and girls, personal factors had more predictive value than socio-environmental factors (Initiation models: for boys: R2 = 0.35 for personal vs. 0.27 for socio-environmental factors; for girls, R2 = 0.46 for personal vs. 0.26 for socio-environmental factors. Persistence models: for boys: R2 = 0.53 for personal vs. 0.33 for socio-environmental factors; for girls, R2 = 0.41 for personal vs. 0.19 for socio

  7. A mindfulness-based intervention to control weight after bariatric surgery: Preliminary results from a randomized controlled pilot trial.

    Science.gov (United States)

    Chacko, Sara A; Yeh, Gloria Y; Davis, Roger B; Wee, Christina C

    2016-10-01

    This study aimed to develop and test a novel mindfulness-based intervention (MBI) designed to control weight after bariatric surgery. Randomized, controlled pilot trial. Beth Israel Deaconess Medical Center, Boston, MA, USA. Bariatric patients 1-5 years post-surgery (n=18) were randomized to receive a 10-week MBI or a standard intervention. Primary outcomes were feasibility and acceptability of the MBI. Secondary outcomes included changes in weight, eating behaviors, psychosocial outcomes, and metabolic and inflammatory biomarkers. Qualitative exit interviews were conducted post-intervention. Major themes were coded and extracted. Attendance was excellent (6 of 9 patients attended ≥7 of 10 classes). Patients reported high satisfaction and overall benefit of the MBI. The intervention was effective in reducing emotional eating at 6 months (-4.9±13.7 in mindfulness vs. 6.2±28.4 in standard, p for between-group difference=0.03) but not weight. We also observed a significant increase in HbA1C (0.34±0.38 vs. -0.06±0.31, p=0.03). Objective measures suggested trends of an increase in perceived stress and symptoms of depression, although patients reported reduced stress reactivity, improved eating behaviors, and a desire for continued mindfulness-based support in qualitative interviews. This novel mindfulness-based approach is highly acceptable to bariatric patients post-surgery and may be effective for reducing emotional eating, although it did not improve weight or glycemic control in the short term. Longer-term studies of mindfulness-based approaches may be warranted in this population. ClinicalTrials.gov identifier NCT02603601. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Overvaluation of shape and weight among overweight children and adolescents with loss of control eating

    Science.gov (United States)

    Goldschmidt, Andrea; Wilfley, Denise E.; Eddy, Kamryn T.; Boutelle, Kerri; Zucker, Nancy; Peterson, Carol B.; Celio-Doyle, Angela; Le Grange, Daniel

    2011-01-01

    Little is known about the phenomenology of pediatric loss of control (LOC) eating. Overvaluation of shape and weight, however, appears to be diagnostically meaningful among binge eating adults. We explored the significance of shape and weight overvaluation among children and adolescents with LOC eating. Participants (n=526) included 149 overweight youth with LOC eating and 377 overweight controls (CON). Participants were categorized as those reporting at least moderate overvaluation (LOC-Mod, n=74; CON-Mod, n=106) or less than moderate overvaluation (LOC-Low, n=75; CON-Low, n=271), and compared on measures of eating-related and general psychopathology. LOC-Mod evidenced lower self-esteem than CON-Low, and greater behavioral problems than CON-Mod and CON-Low, but did not differ from LOC-Low in these domains. With the exception of LOC-Low and CON-Mod, all groups differed on global eating disorder severity, with LOC-Mod scoring the highest. Overvaluation of shape and weight appears to be of questionable importance in defining subtypes of youth with LOC eating. However, as overvaluation and LOC eating each independently predicts eating disorder onset, their confluence may confer even further risk for eating disorder development. Longitudinal studies should address this possibility. Developmentally appropriate discussion about body image disturbance may be indicated in interventions targeting pediatric LOC eating and/or obesity. PMID:21835393

  9. Appetite control after weight loss: what is the role of bloodborne peptides?

    Science.gov (United States)

    Doucet, Eric; Cameron, Jameason

    2007-06-01

    The literature presented in this paper argues that our limited ability to maintain energy balance in a weight-reduced state is the product of our difficulty in compensating for the weight loss-induced reduction in total energy expenditure. The end result, translated into the overwhelming complexity of preserving long-term weight loss, is presented as being a consequence of compromised appetite control. Given the present-day food landscape and the resultant susceptibility to passive overconsumption, the focus of this review will be on the peripheral ("bottom-up") signals (leptin, PYY, ghrelin, and GLP-1) and the evidence highlighting their influence on feeding behaviour. As we continue studying paradigms of body mass reduction, specifically the data emerging from patients of bariatric surgery, it is becoming clearer that counter-regulatory adaptations, possibly through down-(leptin, PYY, and GLP-1) or upregulation (ghrelin) of peptides, have an impact on energy balance. In itself, food deprivation influences some of the peptides that ultimately provide the physiological input for the overt expression of feeding behaviour; these peripheral adaptations are expected to serve as feeding cues--cues that, in the end, can serve to compromise the maintenance of energy balance. In a potentially novel intervention to increase compliance to long-term reductions in energy intake, it is proposed that manipulating the pattern of food intake to favourably alter the profile of gastrointestinal peptides would lead to better dietary control.

  10. Review of innovations in digital health technology to promote weight control.

    Science.gov (United States)

    Thomas, J Graham; Bond, Dale S

    2014-01-01

    Advances in technology have contributed to the obesity epidemic and worsened health by reducing opportunities for physical activity and by the proliferation of inexpensive calorie-dense foods. However, much of the same technology can be used to counter these troublesome trends by fostering the development and maintenance of healthy eating and physical activity habits. In contrast to intensive face-to-face treatments, technology-based interventions also have the potential to reach large numbers of individuals at low cost. The purpose of this review is to discuss studies in which digital technology has been used for behavioral weight control, report on advances in consumer technology that are widely adopted but insufficiently tested, and explore potential future directions for both. Web-based, mobile (eg, smartphone), virtual reality, and gaming technologies are the focus of discussion. The best evidence exists to support the use of digital technology for self-monitoring of weight-related behaviors and outcomes. However, studies are underway that will provide additional, important information regarding how best to apply digital technology for behavioral weight control.

  11. Weight loss herbal intervention therapy (W-LHIT) a non-appetite suppressing natural product controls weight and lowers cholesterol and glucose levels in a murine model.

    Science.gov (United States)

    Yang, Nan; Chung, Danna; Liu, Changda; Liang, Banghao; Li, Xiu-Min

    2014-07-23

    The prevalence of obesity is increasing in industrialized countries. Obesity increases the risk of coronary artery disease, stroke, cancer, hypertension, and type-2 diabetes. Unfortunately, conventional obesity drug treatment is often associated with adverse effects. The objective of this study was to evaluate a novel natural formula, Weight loss herbal intervention therapy (W-LHIT), developed from traditional Chinese medicine, for weight control in a high-fat-diet (HFD) induced obesity murine model. Two sets of experiments were performed. In experiment 1, 14-week-old C57BL/6 J male mice were fed with HFD for 21 days and then separated into 3 weight-matched groups. One group continued on the HFD as obese-controls. Two groups were switched from HFD to normal fat level diet (NFD) and sham or W-LHIT treated. In experiment 2, 25-week-old obese mice, following 2 weeks acclimatization, received either W-LHIT or sham treatment while maintained on HFD. In both sets of experiments, NFD fed, age matched normal weight mice served as normal controls. Body weight and food intake were recorded. Epididymal fat pad weight, serum glucose and cholesterol levels, as well as PPARγ and FABP4 gene expression in epididymal fat tissue were analyzed at the end of the experiment. In experiment 1, W-LHIT treated obese mice lost body weight 12.2 ± 3.8% whereas sham treated mice lost 5.5 ± 2.8% by day 10 after switching from the HFD to the NFD, without reduction of chow consumption. In experiment 2, W-LHIT treated obese mice maintained on the HFD had significantly lower body weight (8 fold less) than the sham treated mice. W-LHIT treatment also reduced epididymal fat pad weight, blood cholesterol and glucose levels versus sham treated mice without reduced chow consumption. In addition, significantly increased PPARγ (peroxisome proliferator activated receptor γ) and FABP4 (fatty acid binding protein 4) gene expression were found in epdidymal fat tissues. Liver and kidney function and

  12. The Breathe Easier through Weight Loss Lifestyle (BE WELL Intervention: A randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Buist A

    2010-03-01

    Full Text Available Abstract Background Obesity and asthma have reached epidemic proportions in the US. Their concurrent rise over the last 30 years suggests that they may be connected. Numerous observational studies support a temporally-correct, dose-response relationship between body mass index (BMI and incident asthma. Weight loss, either induced by surgery or caloric restriction, has been reported to improve asthma symptoms and lung function. Due to methodological shortcomings of previous studies, however, well-controlled trials are needed to investigate the efficacy of weight loss strategies to improve asthma control in obese individuals. Methods/Design BE WELL is a 2-arm parallel randomized clinical trial (RCT of the efficacy of an evidence-based, comprehensive, behavioral weight loss intervention, focusing on diet, physical activity, and behavioral therapy, as adjunct therapy to usual care in the management of asthma in obese adults. Trial participants (n = 324 are patients aged 18 to 70 years who have suboptimally controlled, persistent asthma, BMI between 30.0 and 44.9 kg/m2, and who do not have serious comorbidities (e.g., diabetes, heart disease, stroke. The 12-month weight loss intervention to be studied is based on the principles of the highly successful Diabetes Prevention Program lifestyle intervention. Intervention participants will attend 13 weekly group sessions over a four-month period, followed by two monthly individual sessions, and will then receive individualized counseling primarily by phone, at least bi-monthly, for the remainder of the intervention. Follow-up assessment will occur at six and 12 months. The primary outcome variable is the overall score on the Juniper Asthma Control Questionnaire measured at 12 months. Secondary outcomes include lung function, asthma-specific and general quality of life, asthma medication use, asthma-related and total health care utilization. Potential mediators (e.g., weight loss and change in physical

  13. Satiety-enhancing products for appetite control: science and regulation of functional foods for weight management.

    Science.gov (United States)

    Halford, Jason C G; Harrold, Joanne A

    2012-05-01

    The current review considers satiety-based approaches to weight management in the context of health claims. Health benefits, defined as beneficial physiological effects, are what the European Food Safety Authority bases their recommendations on for claim approval. The literature demonstrates that foods that target within-meal satiation and post-meal satiety provide a plausible approach to weight management. However, few ingredient types tested produce the sustainable and enduring effects on appetite accompanied by the necessary reductions in energy intake required to claim satiety/reduction in hunger as a health benefit. Proteins, fibre types, novel oils and carbohydrates resistant to digestion all have the potential to produce beneficial short-term changes in appetite (proof-of-concept). The challenge remains to demonstrate their enduring effects on appetite and energy intake, as well as the health and consumer benefits such effects provide in terms of optimising successful weight management. Currently, the benefits of satiety-enhancing ingredients to both consumers and their health are under researched. It is possible that such ingredients help consumers gain control over their eating behaviour and may also help reduce the negative psychological impact of dieting and the physiological consequences of energy restriction that ultimately undermine weight management. In conclusion, industry needs to demonstrate that a satiety-based approach to weight management, based on single-manipulated food items, is sufficient to help consumers resist the situational and personal factors that drive overconsumption. Nonetheless, we possess the methodological tools, which when employed in appropriate designs, are sufficient to support health claims.

  14. Mechanisms of weight loss, diabetes control and changes in food choices after gastrointestinal surgery.

    Science.gov (United States)

    Papamargaritis, Dimitrios; Panteliou, Eleftheria; Miras, Alexander D; le Roux, Carel W

    2012-12-01

    The long-term effects of lifestyle changes, diet and medical therapy on obesity are limited. Bariatric surgery is the most effective long-term treatment with the greatest chances for amelioration of obesity-associated complications, including type 2 diabetes mellitus (T2DM). There is increasing evidence in the literature that bariatric operations have a profound effect on human physiology, by reducing hunger, increasing satiety, paradoxically increasing energy expenditure, and even promoting healthy food preferences. Some of these operations improve glucose homeostasis in patients with T2DM independently of weight loss. Changes in the gut hormone levels of glucagon-like peptide 1, peptide YY and ghrelin have been proposed as some of the mediators implicated in changing physiology. The aim of this review is to critically explore the current knowledge on the putative mechanisms of the change in weight and improvement in T2DM glycaemic control after the most commonly performed bariatric operations.

  15. Effect of mirror therapy on upper extremity motor function in stroke patients: a randomized controlled trial

    OpenAIRE

    Gurbuz, Nigar; Afsar, Sevgi Ikbali; Ayaş, Sehri; Cosar, Sacide Nur Saracgil

    2016-01-01

    [Purpose] This study aimed to evaluate the effectiveness of mirror therapy combined with a conventional rehabilitation program on upper extremity motor and functional recovery in stroke patients. [Subjects and Methods] Thirty-one hemiplegic patients were included. The patients were randomly assigned to a mirror (n=16) or conventional group (n=15). The patients in both groups underwent conventional therapy for 4 weeks (60–120 minutes/day, 5 days/week). The mirror group received mirror therapy,...

  16. Effect of mirror therapy on upper extremity motor function in stroke patients: a randomized controlled trial.

    Science.gov (United States)

    Gurbuz, Nigar; Afsar, Sevgi Ikbali; Ayaş, Sehri; Cosar, Sacide Nur Saracgil

    2016-09-01

    [Purpose] This study aimed to evaluate the effectiveness of mirror therapy combined with a conventional rehabilitation program on upper extremity motor and functional recovery in stroke patients. [Subjects and Methods] Thirty-one hemiplegic patients were included. The patients were randomly assigned to a mirror (n=16) or conventional group (n=15). The patients in both groups underwent conventional therapy for 4 weeks (60-120 minutes/day, 5 days/week). The mirror group received mirror therapy, consisting of periodic flexion and extension movements of the wrist and fingers on the non-paralyzed side. The patients in the conventional group performed the same exercises against the non-reflecting face of the mirror. The patients were evaluated at the beginning and end of the treatment by a blinded assessor using the Brunnstrom stage, Fugl-Meyer Assessment (FMA) upper extremity score, and the Functional Independence Measure (FIM) self-care score. [Results] There was an improvement in Brunnstrom stage and the FIM self-care score in both groups, but the post-treatment FMA score was significantly higher in the mirror therapy group than in the conventional treatment group. [Conclusion] Mirror therapy in addition to a conventional rehabilitation program was found to provide additional benefit in motor recovery of the upper extremity in stroke patients.

  17. Effect of mirror therapy on upper extremity motor function in stroke patients: a randomized controlled trial

    Science.gov (United States)

    Gurbuz, Nigar; Afsar, Sevgi Ikbali; Ayaş, Sehri; Cosar, Sacide Nur Saracgil

    2016-01-01

    [Purpose] This study aimed to evaluate the effectiveness of mirror therapy combined with a conventional rehabilitation program on upper extremity motor and functional recovery in stroke patients. [Subjects and Methods] Thirty-one hemiplegic patients were included. The patients were randomly assigned to a mirror (n=16) or conventional group (n=15). The patients in both groups underwent conventional therapy for 4 weeks (60–120 minutes/day, 5 days/week). The mirror group received mirror therapy, consisting of periodic flexion and extension movements of the wrist and fingers on the non-paralyzed side. The patients in the conventional group performed the same exercises against the non-reflecting face of the mirror. The patients were evaluated at the beginning and end of the treatment by a blinded assessor using the Brunnstrom stage, Fugl-Meyer Assessment (FMA) upper extremity score, and the Functional Independence Measure (FIM) self-care score. [Results] There was an improvement in Brunnstrom stage and the FIM self-care score in both groups, but the post-treatment FMA score was significantly higher in the mirror therapy group than in the conventional treatment group. [Conclusion] Mirror therapy in addition to a conventional rehabilitation program was found to provide additional benefit in motor recovery of the upper extremity in stroke patients. PMID:27799679

  18. 117 例极低和超低出生体重儿并发症及结局分析%Complications and outcomes of 117 cases of extremely low birth weight and very low birth weight

    Institute of Scientific and Technical Information of China (English)

    曾军安; 李占魁; 李清红; 邓科委

    2015-01-01

    目的 了解极低出生体重儿( VLBWI)和超低出生体重儿( ELBWI)常见并发症及影响预后的相关因素,为提高极早早产儿救治水平提供参考. 方法 选择西北妇女儿童医院新生儿重症监护病房(NICU)2014年1月1日至12月31日收治的117例VLBWI和ELBWI,根据预后情况分为预后良好组和预后不良组,对其临床资料进行整理和统计分析. 结果 117例患儿中治愈或好转(预后良好)89例(76.1%),放弃治疗或死亡(预后不良)28例(23.9%). VLBWI和ELBWI主要并发症发生率前6位依次是:呼吸窘迫综合征(53.0%),早产儿贫血(50.4%),颅内出血(45.3%),败血症(早发型和晚发型)(36.8%),病理性黄疸(34.2%),呼吸暂停(27.4%). 预后良好组与预后不良组相比较,胎龄较大(t=3.56,P<0.05)、出生体重较重(t=5.30,P<0.05),产时窒息、妊娠期高血压疾病、妊娠糖尿病、肺出血、先天畸形和机械通气率较低(χ2 值分别为4.92、10.73、11.36、5.13、8.79、6.78,均P<0.05). 结论 VLBWI和ELBWI易出现各种并发症,严重并发症及母孕期疾病易导致患儿死亡,并影响家属救治信心,导致预后不良发生,因此,要加强围产期保健,并加强对其并发症的认识,进行及时有效的处理,尽量减少这类患儿的病死率.%Objective To investigate the common complications of very low birth weight infant ( VLBWI) and extremely low birth weight infant ( ELBWI) and related factors influencing prognosis, so as to provide reference for improving the level of treating very preterm infants.Methods From January 1 to December 31 in 2014, totally 117 VLBWIs and ELBWIs treated in neonatal intensive care unit (NICU) of Northwest Women and Children' s Hospital were divided into good prognosis group and poor prognosis group according to prognosis.All these clinical data were collected and analyzed.Results Eighty-nine cases ( 76.1%) were cured or improved ( good prognosis) and 28 cases (23.9%) gave up or died (poor diagnosis

  19. A Randomized Controlled Trial of Two Different Macronutrient Profiles on Weight, Body Composition and Metabolic Parameters in Obese Adolescents Seeking Weight Loss.

    Science.gov (United States)

    Truby, Helen; Baxter, Kimberley; Ware, Robert S; Jensen, Diane E; Cardinal, John W; Warren, Janet M; Daniels, Lynne; Davies, Peter S W; Barrett, Paula; Blumfield, Michelle L; Batch, Jennifer A

    2016-01-01

    Adolescent obesity is difficult to treat and the optimal dietary pattern, particularly in relation to macronutrient composition, remains controversial. This study tested the effect of two structured diets with differing macronutrient composition versus control, on weight, body composition and metabolic parameters in obese adolescents. A randomized controlled trial conducted in a children's hospital. Eighty seven obese youth (means: age 13.6 years, BMI z-score 2.2, waist: height ratio 0.65, 69% female) completed a psychological preparedness program and were then randomized to a short term 'structured modified carbohydrate' (SMC, 35% carbohydrate; 30% protein; 35% fat, n = 37) or a 'structured low fat' (SLF, 55% carbohydrate; 20% protein; 25% fat, n = 36) or a wait listed control group (n = 14). Anthropometric, body composition and biochemical parameters were measured at randomization and after 12 weeks, and analyzed under the intention to treat principle using analysis of variance models. After 12 weeks, data was collected from 79 (91%) participants. BMI z-scores were significantly lower in both intervention groups compared to control after adjusting for baseline values, SLF vs. control, mean difference = -0.13 (95%CI = -0.18, -0.07), Pchanges in weight, body composition and metabolic improvements compared to control. The use of a structured eating system which allows flexibility but limited choices can assist in weight change and the rigid application of a low fat eating pattern is not exclusive in its efficacy. International Clinical Trials Registry ISRCTN49438757.

  20. Weight Loss and the Prevention of Weight Regain: Evaluation of a Treatment Model of Exercise Self-Regulation Generalizing to Controlled Eating.

    Science.gov (United States)

    Annesi, James J; Johnson, Ping H; Tennant, Gisèle A; Porter, Kandice J; Mcewen, Kristin L

    2016-01-01

    For decades, behavioral weight-loss treatments have been unsuccessful beyond the short term. Development and testing of innovative, theoretically based methods that depart from current failed practices is a priority for behavioral medicine. To evaluate a new, theory-based protocol in which exercise support methods are employed to facilitate improvements in psychosocial predictors of controlled eating and sustained weight loss. Women with obesity were randomized into either a comparison treatment that incorporated a print manual plus telephone follow-ups (n = 55) or an experimental treatment of The Coach Approach exercise-support protocol followed after 2 months by group nutrition sessions focused on generalizing self-regulatory skills from an exercise support to a controlled eating context (n = 55). Repeated-measures analysis of variance contrasted group changes in weight, physical activity, fruit and vegetable intake, mood, and exercise- and eating-related self-regulation and self-efficacy over 24 months. Regression analyses determined salient interrelations of change scores over both the weight-loss phase (baseline-month 6) and weight-loss maintenance phase (month 6-month 24). Improvements in all psychological measures, physical activity, and fruit and vegetable intake were significantly greater in the experimental group where a mean weight loss of 5.7 kg (6.1% of initial body weight) occurred at month 6, and was largely maintained at a loss of 5.1 kg (5.4%) through the full 24 months of the study. After establishing temporal intervals for changes in self-regulation, self-efficacy, and mood that best predicted improvements in physical activity and eating, a consolidated multiple mediation model suggested that change in self-regulation best predicted weight loss, whereas change in self-efficacy best predicted maintenance of lost weight. Because for most participants loss of weight remained greater than that required for health benefits, and costs for treatment

  1. Coordinated control strategy for robotic-assisted gait training with partial body weight support

    Institute of Scientific and Technical Information of China (English)

    秦涛; 张立勋

    2015-01-01

    Walking is the most basic and essential part of the activities of daily living. To enable the elderly and non-ambulatory gait-impaired patients, the repetitive practice of this task, a novel gait training robot (GTR) was designed followed the end-effector principle, and an active partial body weight support (PBWS) system was introduced to facilitate successful gait training. For successful establishment of a walking gait on the GTR with PBWS, the motion laws of the GTR were planned to enable the phase distribution relationships of the cycle step, and the center of gravity (COG) trajectory of the human body during gait training on the GTR was measured. A coordinated control strategy was proposed based on the impedance control principle. A robotic prototype was developed as a platform for evaluating the design concepts and control strategies. Preliminary gait training with a healthy subject was implemented by the robotic-assisted gait training system and the experimental results are encouraging.

  2. Light weight portable operator control unit using an Android-enabled mobile phone

    Science.gov (United States)

    Fung, Nicholas

    2011-05-01

    There have been large gains in the field of robotics, both in hardware sophistication and technical capabilities. However, as more capable robots have been developed and introduced to battlefield environments, the problem of interfacing with human controllers has proven to be challenging. Particularly in the field of military applications, controller requirements can be stringent and can range from size and power consumption, to durability and cost. Traditional operator control units (OCUs) tend to resemble laptop personal computers (PCs), as these devices are mobile and have ample computing power. However, laptop PCs are bulky and have greater power requirements. To approach this problem, a light weight, inexpensive controller was created based on a mobile phone running the Android operating system. It was designed to control an iRobot Packbot through the Army Research Laboratory (ARL) in-house Agile Computing Infrastructure (ACI). The hardware capabilities of the mobile phone, such as Wi- Fi communications, touch screen interface, and the flexibility of the Android operating system, made it a compelling platform. The Android based OCU offers a more portable package and can be easily carried by a soldier along with normal gear requirements. In addition, the one hand operation of the Android OCU allows for the Soldier to keep an unoccupied hand for greater flexibility. To validate the Android OCU as a capable controller, experimental data was collected evaluating use of the controller and a traditional, tablet PC based OCU. Initial analysis suggests that the Android OCU performed positively in qualitative data collected from participants.

  3. Randomised controlled trial and economic analysis of an internet-based weight management programme: POWeR+ (Positive Online Weight Reduction).

    Science.gov (United States)

    Little, Paul; Stuart, Beth; Hobbs, Fd Richard; Kelly, Jo; Smith, Emily R; Bradbury, Katherine J; Hughes, Stephanie; Smith, Peter Wf; Moore, Michael V; Lean, Mike Ej; Margetts, Barrie M; Byrne, Christopher D; Griffin, Simon; Davoudianfar, Mina; Hooper, Julie; Yao, Guiqing; Zhu, Shihua; Raftery, James; Yardley, Lucy

    2017-01-01

    BACKGROUND Behavioural counselling with intensive follow-up for obesity is effective, but in resource-constrained primary care settings briefer approaches are needed. OBJECTIVES To estimate the clinical effectiveness and cost-effectiveness of an internet-based behavioural intervention with regular face-to-face or remote support in primary care, compared with brief advice. DESIGN Individually randomised three-arm parallel trial with health economic evaluation and nested qualitative interviews. SETTING Primary care general practices in the UK. PARTICIPANTS Patients with a body mass index of ≥ 30 kg/m(2) (or ≥ 28 kg/m(2) with risk factors) identified from general practice records, recruited by postal invitation. INTERVENTIONS Positive Online Weight Reduction (POWeR+) is a 24-session, web-based weight management intervention completed over 6 months. Following online registration, the website randomly allocated participants using computer-generated random numbers to (1) the control intervention (n = 279), which had previously been demonstrated to be clinically effective (brief web-based information that minimised pressure to cut down foods, instead encouraging swaps to healthier choices and increasing fruit and vegetables, plus 6-monthly nurse weighing); (2) POWeR+F (n = 269), POWeR+ supplemented by face-to-face nurse support (up to seven contacts); or (3) POWeR+R (n = 270), POWeR+ supplemented by remote nurse support (up to five e-mails or brief telephone calls). MAIN OUTCOME MEASURES The primary outcome was a modelled estimate of average weight reduction over 12 months, assessed blind to group where possible, using multiple imputation for missing data. The secondary outcome was the number of participants maintaining a 5% weight reduction at 12 months. RESULTS A total of 818 eligible individuals were randomised using computer-generated random numbers. Weight change, averaged over 12 months, was documented in 666 out of 818 participants (81

  4. Effect of vibration on muscle strength imbalance in lower extremity using multi-control whole body vibration platform.

    Science.gov (United States)

    Yu, Chang Ho; Seo, Shin Bae; Kang, Seung Rok; Kim, Kyung; Kwon, Tae Kyu

    2015-01-01

    This study shows the improvement of muscle activity and muscle strength imbalance in the lower extremities through independent exercise loads in vibration platform. Twenty females of age 20 participated in this study. The subjects were divided into WBV group, with more than 10% of muscle strength imbalance between left and right the lower extremities, and control group, with less than 10% of muscle strength imbalance between left and right the lower extremities. As the prior experiment showed, different exercise postures provide different muscular activities. As a result, the highest muscular activity was found to be in the low squat posture. Therefore, the LS posture was selected for the exercise in this experiment. Vibration intensities were applied to dominant muscle and non-dominant muscle, and the vibration frequency was fixed at 25Hz for the WBV group. The control group was asked to perform the same exercise as the WBV group, without stimulated vibration. This exercise was conducted for a total of 4 weeks. As a result, the WBV group which showed an average deviation of 16% before the experiment, tended to decrease approximately to 5%. In this study, vibration exercise using load deviation is shown to be effective in improving the muscle strength imbalance.

  5. Implementation of Locally Weighted Projection Regression Network for Concurrency Control In Computer Aided Design

    Directory of Open Access Journals (Sweden)

    A.Muthukumaravel

    2011-08-01

    Full Text Available This paper presents implementation of locally weighted projection regression (LWPR network method for concurrency control while developing dial of a fork using Autodesk inventor 2008. The LWPR learns the objects and the type of transactions to be done based on which node in the output layer of the network exceeds a threshold value. Learning stops once all the objects are exposed to LWPR. During testing performance, metrics are analyzed. We have attempted to use LWPR for storing lock information when multi users are working on computer Aided Design (CAD. The memory requirements of the proposed method are minimal in processing locks during transaction.

  6. Cholesterol Metabolism and Weight Reduction in Subjects with Mild Obstructive Sleep Apnoea: A Randomised, Controlled Study

    Directory of Open Access Journals (Sweden)

    Maarit Hallikainen

    2013-01-01

    Full Text Available To evaluate whether parameters of obstructive sleep apnoea (OSA associate with cholesterol metabolism before and after weight reduction, 42 middle-aged overweight subjects with mild OSA were randomised to intensive lifestyle intervention (N=23 or to control group (N=18 with routine lifestyle counselling only. Cholesterol metabolism was evaluated with serum noncholesterol sterol ratios to cholesterol, surrogate markers of cholesterol absorption (cholestanol and plant sterols and synthesis (cholestenol, desmosterol, and lathosterol at baseline and after 1-year intervention. At baseline, arterial oxygen saturation (SaO2 was associated with serum campesterol (P<0.05 and inversely with desmosterol ratios (P<0.001 independently of gender, BMI, and homeostasis model assessment index of insulin resistance (HOMA-IR. Apnoea-hypopnoea index (AHI was not associated with cholesterol metabolism. Weight reduction significantly increased SaO2and serum cholestanol and decreased AHI and serum cholestenol ratios. In the groups combined, the changes in AHI were inversely associated with changes of cholestanol and positively with cholestenol ratios independent of gender and the changes of BMI and HOMA-IR (P<0.05. In conclusion, mild OSA seemed to be associated with cholesterol metabolism independent of BMI and HOMA-IR. Weight reduction increased the markers of cholesterol absorption and decreased those of cholesterol synthesis in the overweight subjects with mild OSA.

  7. Autonomic Nervous System in the Control of Energy Balance and Body Weight: Personal Contributions

    Directory of Open Access Journals (Sweden)

    G. Messina

    2013-01-01

    Full Text Available The prevalence of obesity is increasing in the industrialized world, so that the World Health Organization considers obesity as a “pandemia” in rich populations. The autonomic nervous system plays a crucial role in the control of energy balance and body weight. This review summarizes our own data and perspectives, emphasizing the influence exerted by autonomic nervous system on energy expenditure and food intake, which are able to determine the body weight. Activation of the sympathetic discharge causes an increase in energy expenditure and a decrease in food intake, while reduction of food intake and body weight loss determines a reduction of the sympathetic activity. On the other hand, pathophysiological mechanisms of the obesity involve alterations of the sympathetic nervous system in accordance with the “Mona Lisa Hypothesis,” an acronym for “most obesities known are low in sympathetic activity.” Furthermore, the parasympathetic influences on the energy expenditure are analyzed in this review, showing that an increase in parasympathetic activity can induce a paradoxical enhancement of energy consumption.

  8. Autonomic nervous system in the control of energy balance and body weight: personal contributions.

    Science.gov (United States)

    Messina, G; De Luca, V; Viggiano, An; Ascione, A; Iannaccone, T; Chieffi, S; Monda, M

    2013-01-01

    The prevalence of obesity is increasing in the industrialized world, so that the World Health Organization considers obesity as a "pandemia" in rich populations. The autonomic nervous system plays a crucial role in the control of energy balance and body weight. This review summarizes our own data and perspectives, emphasizing the influence exerted by autonomic nervous system on energy expenditure and food intake, which are able to determine the body weight. Activation of the sympathetic discharge causes an increase in energy expenditure and a decrease in food intake, while reduction of food intake and body weight loss determines a reduction of the sympathetic activity. On the other hand, pathophysiological mechanisms of the obesity involve alterations of the sympathetic nervous system in accordance with the "Mona Lisa Hypothesis," an acronym for "most obesities known are low in sympathetic activity." Furthermore, the parasympathetic influences on the energy expenditure are analyzed in this review, showing that an increase in parasympathetic activity can induce a paradoxical enhancement of energy consumption.

  9. A single FTO gene variant rs9939609 is associated with body weight evolution in a multiethnic extremely obese population that underwent bariatric surgery.

    Science.gov (United States)

    Rodrigues, Gisele K; Resende, Cristina M M; Durso, Danielle F; Rodrigues, Lorena A A; Silva, José Luiz P; Reis, Rodrigo C; Pereira, Solange S; Ferreira, Daniela C; Franco, Gloria R; Alvarez-Leite, Jacqueline

    2015-01-01

    The rs9939609 single nucleotide polymorphism (SNP) in the fat mass and obesity-associated (FTO) gene is involved in obesity. Few studies have been conducted on patients who underwent bariatric surgery. The aim of this study was to evaluate the influence of FTO SNPs on body weight, body composition, and weight regain during a 60-mo follow-up period after bariatric surgery. The rs9939609 was genotyped in 146 individuals using a real-time polymerase chain reaction TaqMan assay. Data for lifestyle, comorbidities, body weight, body mass index (BMI), excess weight loss (EWL), and body composition were obtained before and 6, 12, 18, 24, 36, 48, and 60 mo after surgery. Data were analyzed by comparing two groups of patients according to rs9939609 FTO gene polymorphism. Mixed-regression models were constructed to evaluate the dynamics of body weight, BMI, and EWL over time in female patients. No differences were observed between the groups during the first 24 mo after surgery. After 36, 48, and 60 mo, body weight, fat mass, and BMI were higher, whereas fat-free mass and EWL were lower in the FTO-SNP patient group. Weight regain was more frequent and occurred sooner in the FTO-SNP group. There is a different evolution of weight loss in obese carriers of the FTO gene variant rs9939609 after bariatric surgery. However, this pattern was evident at only 2 y postbariatric surgery, inducing a lower proportion of surgery success and a greater and earlier weight regain. Copyright © 2015 Elsevier Inc. All rights reserved.

  10. The need of a weight management control program in judo: a proposal based on the successful case of wrestling

    Directory of Open Access Journals (Sweden)

    Sterkowicz Stanislaw

    2010-05-01

    Full Text Available Abstract Judo competitions are divided into weight classes. However, most athletes reduce their body weight in a few days before competition in order to obtain a competitive advantage over lighter opponents. To achieve fast weight reduction, athletes use a number of aggressive nutritional strategies so many of them place themselves at a high health-injury risk. In collegiate wrestling, a similar problem has been observed and three wrestlers died in 1997 due to rapid weight loss regimes. After these deaths, the National Collegiate Athletic Association had implemented a successful weight management program which was proven to improve weight management behavior. No similar program has ever been discussed by judo federations even though judo competitors present a comparable inappropriate pattern of weight control. In view of this, the basis for a weight control program is provided in this manuscript, as follows: competition should begin within 1 hour after weigh-in, at the latest; each athlete is allowed to be weighed-in only once; rapid weight loss as well as artificial rehydration (i.e., saline infusion methods are prohibited during the entire competition day; athletes should pass the hydration test to get their weigh-in validated; an individual minimum competitive weight (male athletes competing at no less than 7% and females at no less than 12% of body fat should be determined at the beginning of each season; athletes are not allowed to compete in any weight class that requires weight reductions greater than 1.5% of body weight per week. In parallel, educational programs should aim at increasing the athletes', coaches' and parents' awareness about the risks of aggressive nutritional strategies as well as healthier ways to properly manage body weight.

  11. The need of a weight management control program in judo: a proposal based on the successful case of wrestling

    Science.gov (United States)

    2010-01-01

    Judo competitions are divided into weight classes. However, most athletes reduce their body weight in a few days before competition in order to obtain a competitive advantage over lighter opponents. To achieve fast weight reduction, athletes use a number of aggressive nutritional strategies so many of them place themselves at a high health-injury risk. In collegiate wrestling, a similar problem has been observed and three wrestlers died in 1997 due to rapid weight loss regimes. After these deaths, the National Collegiate Athletic Association had implemented a successful weight management program which was proven to improve weight management behavior. No similar program has ever been discussed by judo federations even though judo competitors present a comparable inappropriate pattern of weight control. In view of this, the basis for a weight control program is provided in this manuscript, as follows: competition should begin within 1 hour after weigh-in, at the latest; each athlete is allowed to be weighed-in only once; rapid weight loss as well as artificial rehydration (i.e., saline infusion) methods are prohibited during the entire competition day; athletes should pass the hydration test to get their weigh-in validated; an individual minimum competitive weight (male athletes competing at no less than 7% and females at no less than 12% of body fat) should be determined at the beginning of each season; athletes are not allowed to compete in any weight class that requires weight reductions greater than 1.5% of body weight per week. In parallel, educational programs should aim at increasing the athletes', coaches' and parents' awareness about the risks of aggressive nutritional strategies as well as healthier ways to properly manage body weight. PMID:20441594

  12. 极低和超低出生体重儿败血症临床分析%Analysis of clinical characteristics and antimicrobial susceptibilities in very low birth weight infants and extremely low birth weight infants with neonatal sepsis

    Institute of Scientific and Technical Information of China (English)

    林素; 吴百威; 王能里; 刘花兰; 胡淑英; 林振浪

    2010-01-01

    目的 了解极低和超低出生体重儿败血症临床特点、病原菌分布及药物敏感情况,以指导临床合理用药.方法 对1999年1月1日至2008年12月31日温州医学院附属育英儿童医院新生儿重症监护病房收治的56例极低和超低出生体重儿败血症(早发型败血症3例,晚发型败血症53例)临床特点、血培养结果及药物敏感情况进行回顾性分析.结果 极低和超低出生体重儿败血症临床表现无特征性.血培养结果阳性43例,以条件致病菌为主,其中新生儿早发型败血症血培养阳性1例.为脑膜炎败血黄杆菌;新生儿晚发型败血症血培养病原菌中,革兰阴性细菌主要是肺炎克雷伯菌(33.3%,14/42);革兰阳性细菌以凝固酶阴性葡萄球菌为首(26.2%,11/42),其次是肠球菌(11.9%,5/42);另有真菌感染2例,为白念珠菌败血症(4.8%,2/42).药物敏感试验方面,所有凝固酶阴性葡萄球菌均为耐苯唑西林凝同酶阴性葡萄球菌,对大部分β-内酰胺类抗生素耐药,对林可霉素、氨基糖苷类、大环内酯类及喹诺酮类抗生素亦不敏感,但对万古霉素未发现耐药,对利福平均敏感;所有肺炎克雷伯菌均产超广谱β-内酰胺酶,仅对碳青霉烯类、氨基糖苷类以及喹诺酮类等少数抗生素敏感.56例败血症患儿治愈43例,死亡13例(包括6例病情恶化放弃治疗),病死率为23.2%.结论极低和超低出生体重儿败血症临床表现缺乏特异性,病原菌主要为条件致病菌,并存在多重耐药,对可疑败血症患儿应及时行病原学检查及药物敏感试验,合理选择抗生素.为减少多重耐药菌感染的发生,应正确合理使用第三代头孢菌素.%Objective To review the basic clinical characteristics and the pathogens and their antimicrobial susceptibilities to neonatal sepsis in very low birth weight infants (VLBWI) and extremely low birth weight infants ( ELBWI) for selection of appropriate antibiotics. Methods A

  13. Influence of ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms on body weight and body composition changes after a controlled weight-loss intervention.

    Science.gov (United States)

    Szendrei, Barbara; González-Lamuño, Domingo; Amigo, Teresa; Wang, Guan; Pitsiladis, Yannis; Benito, Pedro J; Gomez-Candela, Carmen; Calderón, Francisco J; Cupeiro, Rocío

    2016-03-01

    The β-2 and β-3 adrenergic receptors (ADRB2 and ADRB3) are thought to play a role in energy expenditure and lipolysis. However, the effects of the ADRB2 glutamine (Gln) 27 glutamic acid (glutamate) (Glu) and ADRB3 tryptophan (Trp) 64 arginine (Arg) polymorphisms on weight loss remain controversial. The aim of this study was to investigate the effect of these polymorphisms on changes in weight and body composition during a controlled weight-loss program. One hundred seventy-three healthy overweight and obese participants (91 women, 82 men) aged 18-50 years participated in a 22-week-long intervention based on a hypocaloric diet and exercise. They were randomly assigned to 1 of 4 groups: strength, endurance, strength and endurance combined, and physical activity recommendations only. Body weight, body mass index (BMI), and body composition variables were assessed before and after the intervention. Genetic analysis was carried out according to standard protocols. No effect of the ADRB2 gene was shown on final weight, BMI, or body composition, although in the supervised male group, Glu27 carriers tended to have greater weight (p = 0.019, 2.5 kg) and BMI (p = 0.019, 0.88 kg/m(2)) reductions than did noncarriers. There seems to be an individual effect of the ADRB3 polymorphism on fat mass (p = 0.004) and fat percentage (p = 0.036), in addition to an interaction with exercise for fat mass (p = 0.038). After the intervention, carriers of the Arg64 allele had a greater fat mass and fat percentage than did noncarriers (p = 0.004, 2.8 kg). In conclusion, the ADRB2 Gln27Glu and ADRB3 Trp64Arg polymorphisms may influence weight loss and body composition, although the current evidence is weak; however, further studies are necessary to clarify their roles.

  14. Using rolling to develop neuromuscular control and coordination of the core and extremities of athletes.

    Science.gov (United States)

    Hoogenboom, Barbara J; Voight, Michael L; Cook, Gray; Gill, Lance

    2009-05-01

    Rolling is a movement pattern seldom used by physical therapists for assessment and intervention with adult clientele with normal neurologic function. Rolling, as an adult motor skill, combines the use of the upper extremities, core, and lower extremities in a coordinated manner to move from one posture to another. Rolling is accomplished from prone to supine and supine to prone, although the method by which it is performed varies among adults. Assessment of rolling for both the ability to complete the task and bilateral symmetry may be beneficial for use with athletes who perform rotationally-biased sports such as golf, throwing, tennis, and twisting sports such as dance, gymnastics, and figure skating. Additionally, when used as intervention techniques, the rolling patterns have the ability to affect dysfunction of the upper quarter, core, and lower quarter. By applying proprioceptive neuromuscular facilitation (PNF) principles, the therapist may assist patients and clients who are unable to complete a rolling pattern. Examples given in the article include distraction/elongation, compression, and manual contacts to facilitate proper rolling. The combined experience of the four authors is used to describe techniques for testing, assessment, and treatment of dysfunction, using case examples that incorporate rolling. The authors assert that therapeutic use of the developmental pattern of rolling with techniques derived from PNF is a hallmark in rehabilitation of patients with neurologic dysfunction, but can be creatively and effectively utilized in musculoskeletal rehabilitation.

  15. CONTROL DE MALEZA EN DISTRITOS DE RIEGO CON EQUIPOS LIGEROS WEED CONTROL IN IRRIGATION DISTRICTS WITH LIGHT WEIGHT EQUIPMENT

    Directory of Open Access Journals (Sweden)

    José Ramón Lomelí Villanueva

    2010-12-01

    Full Text Available En México el control mecánico de maleza, tradicionalmente se realizaba con maquinaria inadecuada lo cual provocaba daños en los taludes y modificaciones de la sección hidráulica. Para resolver este problema, actualmente se utilizan los equipos ligeros que permiten el desarrollo de una cubierta vegetal, que no interfiere con el flujo del agua y su sistema radical retiene el suelo, lo cual reduce la erosión y mantiene en condiciones estables los taludes. El presente trabajo aborda los aspectos relativos a características y criterios para la selección de los implementos y la secuencia para su utilización. El costo de las operaciones para el control de maleza en canales, drenes y caminos se ha reducido un 39,21% con respecto a utilizar maquinaria inadecuada. La versatilidad de los equipos ligeros permite emplear el implemento más adecuado para cada tipo de maleza. En México, el inventario actual es de 263 equipos ligeros que tienen un potencial de aplicación para el control de la maleza, en la totalidad de los caminos, el 90% de canales y el 70% de drenes de los Distritos de Riego.In Mexico, the mechanical weed control was traditionally carried out with inadequate equipment which caused damage to the slopes and changes in the hydraulic section. In order to solve this problem, light weight equipment is currently being used to allow the development of a vegetation cover to retain soil with no interference with water flow, reducing erosion and maintaining stable conditions in the slopes. This paper addresses aspects related to characteristics and criteria for selecting and sequencing tools for use. The costs of weed control in irrigation channels, drains and roads have been reduced 39.21% compared to using inadequate equipment. The versatility of light weight equipment allows the use of the most appropriate implement for each weed. In Mexico, the current inventory includes 263 light weight devices with which a potential weed control of 90

  16. Postpartum weight retention and breastfeeding among obese women from the randomized controlled Lifestyle in Pregnancy (LiP) trial

    DEFF Research Database (Denmark)

    Vinter, Christina Anne; Jensen, Dorte Møller; Ovesen, Per Glud

    2014-01-01

    up after a randomized controlled intervention trial. SETTING: Two university hospitals in Denmark. POPULATION: A total of 360 women with pregestational body mass index ≥30 kg/m(2) . METHODS: The intervention involved lifestyle changes (diet and exercise) during pregnancy. The control group received......OBJECTIVES: To study the effects of lifestyle intervention in pregnancy on weight retention 6 months postpartum among obese women from the "Lifestyle in Pregnancy" (LiP) study, and to determine associations between breastfeeding with postpartum maternal weight. DESIGN: Six months postpartum follow...... routine pregnancy care. Both groups received standard postnatal care. MAIN OUTCOME MEASURES: Gestational weight gain, postpartum weight retention and breastfeeding. RESULTS: Follow up was completed in 238 women of whom 46% in the intervention group and 57% in the control group had retained weight 6 months...

  17. Clinical analysis of 165 extremely low birth weight infants%超低出生体重儿165例临床分析

    Institute of Scientific and Technical Information of China (English)

    庄严; 高喜容; 刘新晖; 熊月娥; 刘雨; 张琼

    2014-01-01

    Objective To analyze the clinical features and prognosis of extremely low birth weight infants (ELBWI).Method Data of totally 165 hospitalized ELBWI between August 1st,2008 and November 30th,2013 in Hunan Children's Hospital were analyzed.The information of general data and births,prenatal care,delivery room stabilization,transfer information,complications,treatment,outcome and follow up were summarized.Result (1) One hundred and sixty-five ELBWI were involved,their mean gestational age was(28.4 ± 2.4) weeks,mean birth weight (910.9 ± 93.1) g.(2) Rate of delivery in tertiary hospital was 46.7% (77/165)and prenatal steroids exposure was found in 52.1% (86/165).None of the cases were treated with continuous positive airway pressure (CPAP) in delivery room.(3) Rate of infants who were transfered to the class Ⅲ b neonatal ward within 12 hours after birth was 58.8% (97/165).(4) The main complications of them included neonatal respiratory distress syndrome (NRDS,77.0%,127/165),bronchopulmonary dysplasia (BPD,70.1%,75/107),patent ductus arteriosus (PDA,50.0%,40/80),preterm retinopathy (ROP,43.0%,46/107),sepsis 39.4% (65/165),intraventricular hemorrhage (IVH,34.8%,49/141),necrotizing enterocolitis(NEC,8.0%,7/88).(5) Treatment:97.6%(161/165) received oxygen therapy and 66.1% (109/165) received mechanical ventilation,55.2% (91/165) used CPAP.89.8% (114/127) of the NRDS used PS; 44.0% (33/75) of the BPD used low dose dexamethasone,32.0% (24/75) used low dose nitric oxide; 60.0% (24/40)of the PDA used medication.32.6% (15/46) of the ROP received laser photocoagulation.The average time of beginning enteral feeding was 2.0 d,the mean time to achieve full gastrointestinal feeding was 43.4 d.(6) Outcome:rate of survival in 165 cases with ELBWI was 51.5% (85/165),treatment was abandoned in 37.6% (62/165),total mortality was 48.5% (80/165).There were significant difference in survival rate between different birth weight group

  18. Effect of nonsurgical periodontal therapy and strict plaque control on preterm/low birth weight: a randomized controlled clinical trial.

    Science.gov (United States)

    Weidlich, Patricia; Moreira, Carlos Heitor C; Fiorini, Tiago; Musskopf, Marta L; da Rocha, José M; Oppermann, Maria Lucia R; Aass, Anne M; Gjermo, Per; Susin, Cristiano; Rösing, Cassiano K; Oppermann, Rui V

    2013-01-01

    This randomized controlled clinical trial was carried out to assess the effect of comprehensive nonsurgical periodontal treatment and strict plaque control performed during pregnancy on the reduction of preterm and/or low birth weight rates (PTLBW). Three hundred and three women were randomly allocated to receive periodontal treatment either during pregnancy (n = 147, test group) or after delivery (n = 156, control group). During pregnancy, the control group received only one session of supragingival scaling and oral hygiene instruction. In contrast, the test group received comprehensive periodontal treatment including multiple sessions of scaling and root planing, oral hygiene instructions, and frequent maintenance visits. At baseline, periodontal inflammation was observed in approximately 50% of sites and attachment loss affected controls, women in the test group had significant reductions in the percentage of sites with plaque (48.5% vs. 10.3%, p control significantly improved periodontal health; however, no reduction of PTLBW rates was observed. Thus, remaining periodontal inflammation posttreatment cannot explain the lack of effect of periodontal treatment on PTLBW. Clinical relevance This study demonstrated that periodontal diseases may be successfully treated during pregnancy. Our results do not support a potential beneficial effect of periodontal treatment on PTLBW.

  19. The family as a determinant of stunting in children living in conditions of extreme poverty: a case-control study

    Science.gov (United States)

    Reyes, Hortensia; Pérez-Cuevas, Ricardo; Sandoval, Araceli; Castillo, Raúl; Santos, José Ignacio; Doubova, Svetlana V; Gutiérrez, Gonzalo

    2004-01-01

    Background Malnutrition in children can be a consequence of unfavourable socioeconomic conditions. However, some families maintain adequate nutritional status in their children despite living in poverty. The aim of this study was to ascertain whether family-related factors are determinants of stunting in young Mexican children living in extreme poverty, and whether these factors differ between rural or urban contexts. Methods A case-control study was conducted in one rural and one urban extreme poverty level areas in Mexico. Cases comprised stunted children aged between 6 and 23 months. Controls were well-nourished children. Independent variables were defined in five dimensions: family characteristics; family income; household allocation of resources and family organisation; social networks; and child health care. Information was collected from 108 cases and 139 controls in the rural area and from 198 cases and 211 controls in the urban area. Statistical analysis was carried out separately for each area; unconditional multiple logistic regression analyses were performed to obtain the best explanatory model for stunting. Results In the rural area, a greater risk of stunting was associated with father's occupation as farmer and the presence of family networks for child care. The greatest protective effect was found in children cared for exclusively by their mothers. In the urban area, risk factors for stunting were father with unstable job, presence of small social networks, low rate of attendance to the Well Child Program activities, breast-feeding longer than six months, and two variables within the family characteristics dimension (longer duration of parents' union and migration from rural to urban area). Conclusions This study suggests the influence of the family on the nutritional status of children under two years of age living in extreme poverty areas. Factors associated with stunting were different in rural and urban communities. Therefore, developing and

  20. The family as a determinant of stunting in children living in conditions of extreme poverty: a case-control study

    Directory of Open Access Journals (Sweden)

    Doubova Svetlana V

    2004-11-01

    Full Text Available Abstract Background Malnutrition in children can be a consequence of unfavourable socioeconomic conditions. However, some families maintain adequate nutritional status in their children despite living in poverty. The aim of this study was to ascertain whether family-related factors are determinants of stunting in young Mexican children living in extreme poverty, and whether these factors differ between rural or urban contexts. Methods A case-control study was conducted in one rural and one urban extreme poverty level areas in Mexico. Cases comprised stunted children aged between 6 and 23 months. Controls were well-nourished children. Independent variables were defined in five dimensions: family characteristics; family income; household allocation of resources and family organisation; social networks; and child health care. Information was collected from 108 cases and 139 controls in the rural area and from 198 cases and 211 controls in the urban area. Statistical analysis was carried out separately for each area; unconditional multiple logistic regression analyses were performed to obtain the best explanatory model for stunting. Results In the rural area, a greater risk of stunting was associated with father's occupation as farmer and the presence of family networks for child care. The greatest protective effect was found in children cared for exclusively by their mothers. In the urban area, risk factors for stunting were father with unstable job, presence of small social networks, low rate of attendance to the Well Child Program activities, breast-feeding longer than six months, and two variables within the family characteristics dimension (longer duration of parents' union and migration from rural to urban area. Conclusions This study suggests the influence of the family on the nutritional status of children under two years of age living in extreme poverty areas. Factors associated with stunting were different in rural and urban communities

  1. Challenges of a community based pragmatic, randomised controlled trial of weight loss maintenance.

    Science.gov (United States)

    Randell, Elizabeth; McNamara, Rachel; Shaw, Christine; Espinasse, Aude; Simpson, Sharon Anne

    2015-12-18

    Randomised controlled trials (RCTs) have a reputation for being inherently difficult to deliver as planned and often face unforeseen challenges and delays, particularly in relation to organisational and governance difficulties, participant interest, constraints due to allocation of costs, local investigator interest and lengthy bureaucracy. Recruitment is often difficult and the challenges faced often impact on the cost and delivery of a successful trial within the funded period. This paper reflects upon the challenges faced in delivering a pragmatic RCT of weight loss maintenance in a community setting and suggests some potential solutions. The weight loss maintenance in adults trial aimed to evaluate the impact of a 12 month, individually tailored weight maintenance intervention on BMI 3 years from randomisation. Participants were recruited primarily from participant identification centres (PICs)-GP surgeries, exercise on referral schemes and slimming world. The intervention was delivered in community settings. A recruitment strategy implementation plan was drafted to address and monitor poor recruitment. Delays in opening and recruitment were experienced early on. Some were beyond the control of the study team such as; disagreement over allocation of national health service costs and PIC classification as well as difficulties in securing support from research networks. That the intervention was delivered in community settings was often at the root of these issues. Key items to address at the design stage of future trials include feasibility of eligibility criteria. The most effective element of the recruitment implementation plan was to refocus sources of recruitment and target only those who could fulfil the eligibility criteria immediately. Learnings from this trial should be kept in mind by those designing similar studies in the future. Considering potential governance, cost and research network support implications at the design stage of pragmatic trials of

  2. The Relevance of Maternal Socioeconomic Characteristics for Low Birth Weight – a Case-Control Study

    Science.gov (United States)

    Altenhöner, T.; Köhler, M.; Philippi, M.

    2016-01-01

    Introduction: The number of children born underweight (low birth weight, LBW) is increasing despite extensive prevention and screening programmes. The cost is high for the health system, and affected children are burdened with health predictors that can affect them negatively throughout their lives. This study investigates to what extent socioeconomic factors, in addition to known medical causes and the health behaviour of pregnant women, influence LBW. Materials and Methods: In this case-control study 131 mothers of singletons with a birth weight ≤ 2500 g (cases) and 323 mothers of normal birth weight babies (controls) were interviewed with respect to socioeconomic status, health behaviour and stress in the workplace. Medical data were collected by specialist staff using a questionnaire. Results: Independent of medical diagnosis and health behaviour, women with lower level education (OR [95 % CI] = 2.24 [1.12; 4.51]) and those who were not working (OR [95 % CI] = 1.82 [1.10; 3.00]) were more likely to have an LBW baby. No effect was shown for immigrant background (OR [95 % CI] = 1.14 [0.59; 2.21]) or stress in the workplace (OR [95 % CI] = 1.17 [0.90; 1.51]). Discussion and Conclusion: These results show that the association between social and health inequalities starts from before birth. In order to reduce the rising number of babies born underweight, socioeconomic determinants in the care and supervision of pregnant women should systematically receive more attention to enable appropriate early preventive strategies to be implemented. PMID:27065486

  3. Emerging role of glial cells in the control of body weight

    Science.gov (United States)

    García-Cáceres, Cristina; Fuente-Martín, Esther; Argente, Jesús; Chowen, Julie A.

    2012-01-01

    Glia are the most abundant cell type in the brain and are indispensible for the normal execution of neuronal actions. They protect neurons from noxious insults and modulate synaptic transmission through affectation of synaptic inputs, release of glial transmitters and uptake of neurotransmitters from the synaptic cleft. They also transport nutrients and other circulating factors into the brain thus controlling the energy sources and signals reaching neurons. Moreover, glia express receptors for metabolic hormones, such as leptin and insulin, and can be activated in response to increased weight gain and dietary challenges. However, chronic glial activation can be detrimental to neurons, with hypothalamic astrocyte activation or gliosis suggested to be involved in the perpetuation of obesity and the onset of secondary complications. It is now accepted that glia may be a very important participant in metabolic control and a possible therapeutical target. Here we briefly review this rapidly advancing field. PMID:24024117

  4. The systems of automatic weight control of vehicles in the road and rail transport in Poland

    Directory of Open Access Journals (Sweden)

    2011-09-01

    Full Text Available . Condition of roads in Poland, despite the on-going modernisation works is still unsatisfactory. One reason is the excessive wear caused by overloaded vehicles. This problem also applies to rail transport, although to a much lesser extent. One solution may be the system of automatic weight control of road and rail vehicles. The article describes the legal and organizational conditions of oversize vehicles inspection in Poland. Characterized current practices weighing road vehicles, based on measurements of static technology. The article includes the description of the existing applications of the automatic dynamic weighing technology, known as systems WIM (Weigh in Motion. Additionally, the weighing technology and construction of weighing stands in road and rail are characterized. The article ends with authors' conclusions indicating the direction and ways of improving the weighing control systems for vehicles.

  5. Physical Activity, Exercise, And Nutrition Interventions For Weight Control In African American Women

    Directory of Open Access Journals (Sweden)

    Matthew Asare

    2010-01-01

    Full Text Available The purpose of this paper was to review the physical activity, exercise, and nutritionrelated weight control interventions done with African American women that were publishedbetween 2006 and 2010 and suggest ways of enhancing these interventions. A total of 13 studiesmet the inclusion criteria. The review found significant results with regard to impact ofintervention. Twelve of those studies revealed significant increase in physical activity and weightreduction behavior. In terms of use of theory in designing the interventions only five interventionsused a theory. In three of those cases social cognitive theory was used. Appropriate sample sizewas found to be the major strength of most of the interventions. Six interventions usedrandomized controlled design. Recommendations for enhancing the effectiveness of physicalactivity interventions in African American women are presented.

  6. Life-style modification for weight control to improve diabetes health status.

    Science.gov (United States)

    Wierenga, M E

    1994-04-01

    The purpose of this study was to describe the relationship among variables which are associated with life-style modification, knowledge of diabetes, social support, health practices, and body mass index, to examine their effect on health status, and to test the effectiveness of a community based life-style modification program for weight control. Adults (n = 66) with non-insulin-dependent diabetes mellitus participated in either a treatment or control group. The treatment consisted of 5 weekly 90-min sessions on modifying eating and exercise patterns. All participants completed a personal resource questionnaire (PRQ), health practices survey (HPS), and diabetes health status questionnaire (DHS) at intake, 5 weeks, and 4 months. Knowledge of diabetes was assessed only at intake. Knowledge of diabetes, social support, and health practices explained 27% of the variance in health status, but health practices explained the largest (18%) proportion of the variance and was the only study variable significantly affected by the life-style modification program.

  7. Prevalence of Disordered Eating and Pathogenic Weight Control Behaviors among NCAA Division I Female Collegiate Gymnasts and Swimmers

    Science.gov (United States)

    Anderson, Carlin; Petrie, Trent A.

    2012-01-01

    Eating disorders and related weight control behaviors, such as excessive exercising and restrictive eating, represent serious health problems for girls and women in the United States and other industrialized nations. Female athletes, in particular, have been identified as a subgroup to study because of the unique weight, performance, and body…

  8. Efficacy of Continuing Education in Improving Pharmacists' Competencies for Providing Weight Management Service: Three-Arm Randomized Controlled Trial

    Science.gov (United States)

    Sarayani, Amir; Rashidian, Arash; Gholami, Kheirollah; Torkamandi, Hassan; Javadi, Mohammadreza

    2012-01-01

    Introduction: Weight management is a new public health role for community pharmacists in many countries. Lack of expertise is one of the key barriers to counseling obese patients. We evaluated the comparative efficacy of three alternative continuing education (CE) meetings on weight management. Methods: We designed a randomized controlled trial…

  9. The Relationship Between Weights and Control Vertices of Two Rational NURBS Curves Representing the Same Curve Parametrically and Geometrically

    Institute of Scientific and Technical Information of China (English)

    冯仁忠; 王仁宏; 等

    2003-01-01

    The paper discusses the relationship between weights and control vertices of two rational NURBS curves of degree two or three with all weights lager than zero when they represent the same curve parametrically and geometrically,and gives sufficient and necessary conditions for coincidences of two rational NURBS curvbes in non-degeneracy case.

  10. Prevalence of Disordered Eating and Pathogenic Weight Control Behaviors among NCAA Division I Female Collegiate Gymnasts and Swimmers

    Science.gov (United States)

    Anderson, Carlin; Petrie, Trent A.

    2012-01-01

    Eating disorders and related weight control behaviors, such as excessive exercising and restrictive eating, represent serious health problems for girls and women in the United States and other industrialized nations. Female athletes, in particular, have been identified as a subgroup to study because of the unique weight, performance, and body…

  11. Nonlinear Model Predictive Control of A Gasoline HCCI Engine Using Extreme Learning Machines

    OpenAIRE

    Janakiraman, Vijay Manikandan; Nguyen, XuanLong; Assanis, Dennis

    2015-01-01

    Homogeneous charge compression ignition (HCCI) is a futuristic combustion technology that operates with a high fuel efficiency and reduced emissions. HCCI combustion is characterized by complex nonlinear dynamics which necessitates a model based control approach for automotive application. HCCI engine control is a nonlinear, multi-input multi-output problem with state and actuator constraints which makes controller design a challenging task. Typical HCCI controllers make use of a first princi...

  12. Use and Complications of Operative Control of Arterial Inflow in Combat Casualties with Traumatic Lower-extremity Amputations Caused by Improvised Explosive Devices

    Science.gov (United States)

    2013-08-01

    injuries: patterns of injuries and resource utilization associated with the multiple extremity amputee . J Surg Orthop Adv. 2012;21:32Y37. 11. Andersen RC...methods of proximal control in high wartime lower-extremity amputees . Although some casualties will have abdominal injuries that necessitate...of suprainguinal vascular control and complications that arose. In cases where multiple levels of control were used, data on all vessels were collected

  13. Exponentially Weighted Moving Average Control Schemes for Assessing Hospital Organizational Performance

    Directory of Open Access Journals (Sweden)

    Michele Scagliarini

    2016-06-01

    Full Text Available Exponentially weighted moving average (EWMA control charts have been successfully used in recent years in several areas of healthcare. Most of these applications have concentrated on the problem of detecting shifts in the mean level of a process. The EWMA chart for monitoring the variability has received, in general, less attention than its counterpart for the mean, although equally important and, to the best of our knowledge, it has never been used in the healthcare framework. In this work, EWMA control charts were applied retrospectively for monitoring the mean and variability of a hospital organizational performance indicator. The aim was to determine whether EWMA control charts can be used as a comprehensive approach for assessing the steady-state behaviour of the process and for early detection of changes indicating either improvement or deterioration in the performance of healthcare organizations. The results showed that the EWMA control schemes generate easy-to-read data displays that reflect process performance allowing a continuous monitoring and prompt detection of changes in process performance. Currently, hospital managers are designing an operating room dashboard which also includes the EWMA control charts.

  14. An innovative solid oral nutritional supplement to fight weight loss and anorexia: open, randomised controlled trial of efficacy in institutionalised, malnourished older adults.

    Science.gov (United States)

    Pouyssegur, Valerie; Brocker, Patrice; Schneider, Stéphane M; Philip, Jean Luc; Barat, Philippe; Reichert, Ewa; Breugnon, Frederic; Brunet, Didier; Civalleri, Bruno; Solere, Jean Paul; Bensussan, Line; Lupi-Pegurier, Laurence

    2015-03-01

    To evaluate the impact of a solid nutritional supplement on the weight gain of institutionalised older adults>70 years with protein-energy malnutrition. The innovation of these high-protein and high-energy cookies was the texture adapted to edentulous patients (Protibis®, Solidages, France). An open, multicentre, randomised controlled trial. Seven nursing homes. One hundred and seventy-five malnourished older adults, aged 86±8 years. All participants received the standard institutional diet. In addition, Intervention group participants received eight cookies daily (11.5 g protein; 244 kcal) for 6 weeks (w0-w6). Five visits (w-4, w0, w6, w10 and w18). Percentage of weight gain from w0 to w6 (body mass in kg). Appetite, rated using a numerical scale (0: no appetite to 10: extremely good appetite); current episodes of pressure ulcers and diarrhea. Average weight increased in Intervention group (n=88) compared with Control group (n=87) without cookies supplementation (+1.6 versus -0.7%, P=0.038). Weight gain persisted 1 month (+3.0 versus -0.2%, P=0.025) and 3 months after the end of cookies consumption (+3.9 versus -0.9%, P=0.003), with diarrhea reduction (P=0.027). There was a synergistic effect with liquid/creamy dietary supplements. Subgroup analysis confirmed the positive impact of cookies supplementation alone on weight increase (P=0.024), appetite increase (P=0.009) and pressure ulcers reduction (P=0.031). The trial suggested that, to fight against anorexia, the stimulation of touch (finger food; chewing, even on edentulous gums) and hearing (intra-oral sounds) could be valuable alternatives to sight, smell and taste alterations. © The Author 2014. Published by Oxford University Press on behalf of the British Geriatrics Society. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

  15. Influence of the control system on wind turbine reliability in extreme turbulence

    DEFF Research Database (Denmark)

    Abdallah, Imad; Natarajan, Anand; Sørensen, J. D.

    2014-01-01

    alleviation control features. It is shown that large uncertainties in inflow conditions and turbulence can be significantly reduced while maintaining an acceptable structural reliability through the use of advanced structural load alleviation control features. However, that comes at a cost of increased...... controller complexity and loss in annual energy production....

  16. A Comparison of Shewhart Control Charts based on Normality, Nonparametrics, and Extreme-Value Theory

    NARCIS (Netherlands)

    Ion, R.A.; Does, R.J.M.M.; Klaassen, C.A.J.

    2000-01-01

    Several control charts for individual observations are compared. The traditional ones are the well-known Shewhart control charts with estimators for the spread based on the sample standard deviation and the average of the moving ranges. The alternatives are nonparametric control charts, based on emp

  17. [Dietary habits, attitudes toward weight control, and subjective symptoms of fatigue in young women in Japan].

    Science.gov (United States)

    Osako, Mai; Takayama, Tomoko; Kira, Shohei

    2005-05-01

    This paper describes dietary habits and attitudes toward body weight control of college women in Japan and examines their relationships with subjective symptoms of fatigue. We also discuss strategies to promote better diets among young adults. Self-reported questionnaires were distributed to 286 young women aged 18 to 25 years; 275 of these were analyzed. The study found that more than half of the women were concerned about nutritional balance and calories. Yet thirty percent ate "a single-item meal (i.e., bread, rice bowl, noodles) two or more times a day," while roughly one half skipped breakfast "sometimes" or "always." A majority ate vegetables "almost never" and consumed instant foods, confectionery, or sugary drinks "almost daily." Subjective symptoms of fatigue were significantly correlated with a higher frequency of irregular meal-taking, single-item meals, between-meal snacking, missed breakfasts, non-vegetable diets, non-fruit diets, and instant foods and confectionery. About sixty percent of the women in the study considered their bodies to be "slightly fat or overweight" while 79.5% indicated a desire to "lose weight". On average, the participants' ideal BMI was 18.7 (+/- 1.2) while the ideal body weight was 47.2 (+/- 4.1) kg, approximately 4 kg under actual average body weight. Subjective symptoms of fatigue were stronger among women who considered themselves "slightly fat or overweight". Likewise, symptoms were stronger to the extent that a participant's ideal BMI was below her actual BMI. Many women in this study desired to lose weight although they were not overweight by objective measures. The study suggests that subjective symptoms of fatigue are not the result of individual dietary habits, but rather of a lifestyle that reach to series of dietary habits connected to subjective symptoms of fatigue. The study also confirms the importance both of encouraging young women not just to eat well but to lead lifestyles in which they do not skip meals and

  18. Regional amplification of projected changes in extreme temperatures strongly controlled by soil moisture-temperature feedbacks

    Science.gov (United States)

    Vogel, M. M.; Orth, R.; Cheruy, F.; Hagemann, S.; Lorenz, R.; Hurk, B. J. J. M.; Seneviratne, S. I.

    2017-02-01

    Regional hot extremes are projected to increase more strongly than global mean temperature, with substantially larger changes than 2°C even if global warming is limited to this level. We investigate the role of soil moisture-temperature feedbacks for this response based on multimodel experiments for the 21st century with either interactive or fixed (late 20th century mean seasonal cycle) soil moisture. We analyze changes in the hottest days in each year in both sets of experiments, relate them to the global mean temperature increase, and investigate processes leading to these changes. We find that soil moisture-temperature feedbacks significantly contribute to the amplified warming of the hottest days compared to that of global mean temperature. This contribution reaches more than 70% in Central Europe and Central North America. Soil moisture trends are more important for this response than short-term soil moisture variability. These results are relevant for reducing uncertainties in regional temperature projections.

  19. Extreme ultraviolet (EUV) surface modification of polytetrafluoroethylene (PTFE) for control of biocompatibility

    Energy Technology Data Exchange (ETDEWEB)

    Ahad, Inam Ul, E-mail: inam-ul.ahad@wat.edu.pl [Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw (Poland); Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Faculty of Engineering & Computing, Dublin City University, Dublin 9 (Ireland); Butruk, Beata [Department of Biotechnology and Bioprocess Engineering, Warsaw University of Technology, Ul. Waryńskiego 1, 00-645 Warsaw (Poland); Ayele, Mesfin; Budner, Bogusław; Bartnik, Andrzej; Fiedorowicz, Henryk [Institute of Optoelectronics, Military University of Technology, 00-908 Warsaw (Poland); Ciach, Tomasz [Department of Biotechnology and Bioprocess Engineering, Warsaw University of Technology, Ul. Waryńskiego 1, 00-645 Warsaw (Poland); Brabazon, Dermot [Advanced Processing Technology Research Centre, School of Mechanical and Manufacturing Engineering, Faculty of Engineering & Computing, Dublin City University, Dublin 9 (Ireland)

    2015-12-01

    Extreme ultraviolet (EUV) surface modification of polytetrafluoroethylene (PTFE) was performed in order to enhance the degree of biocompatibility. Polymer samples were irradiated by different number of EUV shots using a laser–plasma based EUV source in the presence of nitrogen gas. The physical and chemical properties of EUV modified PTFE samples were studied using Atomic Force Microscopy, X-ray photoelectron spectroscopy and water contact angle (WCA) methods. Pronounced wall type micro and nano-structures appeared on the EUV treated polymer surfaces resulting in increased surface roughness and hydrophobicity. Stronger cell adhesion and good cell morphology were observed on EUV modified surfaces by in-vitro cell culture studies performed using L929 fibroblasts.

  20. A Randomized Controlled Trial of Two Different Macronutrient Profiles on Weight, Body Composition and Metabolic Parameters in Obese Adolescents Seeking Weight Loss.

    Directory of Open Access Journals (Sweden)

    Helen Truby

    Full Text Available Adolescent obesity is difficult to treat and the optimal dietary pattern, particularly in relation to macronutrient composition, remains controversial. This study tested the effect of two structured diets with differing macronutrient composition versus control, on weight, body composition and metabolic parameters in obese adolescents.A randomized controlled trial conducted in a children's hospital.Eighty seven obese youth (means: age 13.6 years, BMI z-score 2.2, waist: height ratio 0.65, 69% female completed a psychological preparedness program and were then randomized to a short term 'structured modified carbohydrate' (SMC, 35% carbohydrate; 30% protein; 35% fat, n = 37 or a 'structured low fat' (SLF, 55% carbohydrate; 20% protein; 25% fat, n = 36 or a wait listed control group (n = 14. Anthropometric, body composition and biochemical parameters were measured at randomization and after 12 weeks, and analyzed under the intention to treat principle using analysis of variance models.After 12 weeks, data was collected from 79 (91% participants. BMI z-scores were significantly lower in both intervention groups compared to control after adjusting for baseline values, SLF vs. control, mean difference = -0.13 (95%CI = -0.18, -0.07, P<0.001; SMC vs. control, -0.14 (-0.19, -0.09, P<0.001, but there was no difference between the two intervention diet groups: SLF vs. SMC, 0.00 (-0.05, 0.04, P = 0.83.Both dietary patterns resulted in similar changes in weight, body composition and metabolic improvements compared to control. The use of a structured eating system which allows flexibility but limited choices can assist in weight change and the rigid application of a low fat eating pattern is not exclusive in its efficacy.International Clinical Trials Registry ISRCTN49438757.

  1. Associations between body mass index, weight control concerns and behaviors, and eating disorder symptoms among non-clinical Chinese adolescents

    Directory of Open Access Journals (Sweden)

    Hu Xiaoqi

    2010-06-01

    Full Text Available Abstract Background Previous research with adolescents has shown associations of body weight, weight control concerns and behaviors with eating disorder symptoms, but it is unclear whether these associations are direct or whether a mediating effect exists. This study was conducted to investigate the prevalence of overweight and obesity, weight control concerns and behaviors, and eating disorder symptoms and to examine the mediating function of weight control concerns and behaviors on the relationship between body mass index (BMI and eating disorder symptoms among non-clinical adolescents in China. Methods A cross-sectional survey among 2019 adolescent girls and 1525 adolescent boys in the 7th, 8th, 10th and 11th grades from seven cities in China was conducted. Information on weight control concerns and behaviors, and eating disorder symptoms (Eating Disorder Inventory-3 were collected from the adolescents using a self-administrated questionnaire. Results Weight control concerns and behaviors, and eating disorder symptoms were prevalent among the study population. A high proportion of adolescents scored at or above the threshold on the eating disorder inventory (EDI subscale such as bulimia, interoceptive deficits, perfectionism, and maturity fears, which indicated eating disorder symptoms. High BMI was significantly associated with high score of drive for thinness, body dissatisfaction, bulimia, low self-esteem, interceptive deficits and maturity fears, so do perceived body weight status. Almost all weight control concerns and behaviors we investigated were significantly associated with high EDI subscale scores. When weight control concerns were added to the model, as shown in the model, the association between BMI and tendency of drive to thinness and bulimia was attenuated but still kept significant. The association between BMI and body dissatisfaction were no further significant. The association of BMI and drive for thinness, body

  2. Early weaning to reduce tissue mobilization in lactating sows and milk supplementation to enhance pig weaning weight during extreme heat stress.

    Science.gov (United States)

    Spencer, J D; Boyd, R D; Cabrera, R; Allee, G L

    2003-08-01

    This study was conducted to determine the effect of reduced lactation length and supplemental milk replacer (MR) during high ambient temperatures. Thirty nine primiparous and 100 multiparous sows (PIC, Franklin, KY, C-22) were used in a 2 x 2 x 2 factorial arrangement of treatments. Treatments consisted of two lactation room temperatures (21 degrees C [TN] and 32 degrees C [HOT]), two lactation lengths (14 or 19 d), and two parity groups (primiparous, multiparous). Pigs were either: 1) sow-reared to 19 d or 2) sow-reared to 14 d, and then reared to 19 d with MR after sow removal. All sows were fed the same diet (1.07% lysine, 3,366 kcal of ME/kg). Sows were weighed and ultrasound for backfat thickness (BF) and longissimus muscle area (LMA) within 6 h after farrowing and at the time of sow removal (d 14 or 19). Pigs were individually weighed at weaning (d 19) and after a 47-d nursery period (d 66). Heat stress increased sow weight loss (-13.35 kg, P Milk replacer decreased the difference normally observed in 19-d weights between primiparous and multiparous sow-reared pigs in TN. Pigs fed MR in both environments and nursing multiparous sows had improved weight gains in the nursery compared with pigs nursing sows to 19 d (428 vs. 406 g/d, respectively; P milk replacer to preserve the sow and to restore pig weaning weights and nursery end weights under heat stress.

  3. Changes in body weight and food choice in those attempting smoking cessation: a cluster randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Leslie Wilma S

    2012-05-01

    Full Text Available Abstract Background Fear of weight gain is a barrier to smoking cessation and significant cause of relapse for many people. The provision of nutritional advice as part of a smoking cessation programme may assist some in smoking cessation and perhaps limit weight gain. The aim of this study was to determine the effect of a structured programme of dietary advice on weight change and food choice, in adults attempting smoking cessation. Methods Cluster randomised controlled design. Classes randomised to intervention commenced a 24-week intervention, focussed on improving food choice and minimising weight gain. Classes randomised to control received “usual care”. Results Twenty-seven classes in Greater Glasgow were randomised between January and August 2008. Analysis, including those who continued to smoke, showed that actual weight gain and percentage weight gain was similar in both groups. Examination of data for those successful at giving up smoking showed greater mean weight gain in intervention subjects (3.9 (SD 3.1 vs. 2.7 (SD 3.7 kg. Between group differences were not significant (p = 0.23, 95% CI −0.9 to 3.5. In comparison to baseline improved consumption of fruit and vegetables and breakfast cereal were reported in the intervention group. A higher percentage of control participants continued smoking (74% vs. 66%. Conclusions The intervention was not successful at minimising weight gain in comparison to control but was successful in facilitating some sustained improvements in the dietary habits of intervention participants. Improved quit rates in the intervention group suggest that continued contact with advisors may have reduced anxieties regarding weight gain and encouraged cessation despite weight gain. Research should continue in this area as evidence suggests that the negative effects of obesity could outweigh the health benefits achieved through reductions in smoking prevalence. Trial registration Current Controlled Trials

  4. The effect of a motivational intervention on weight loss is moderated by level of baseline controlled motivation

    Directory of Open Access Journals (Sweden)

    Tate Deborah F

    2010-01-01

    Full Text Available Abstract Background Clinic-based behavioral weight loss programs are effective in producing significant weight loss. A one-size-fits-all approach is often taken with these programs. It may be beneficial to tailor programs based on participants' baseline characteristics. Type and level of motivation may be an important factor to consider. Previous research has found that, in general, higher levels of controlled motivation are detrimental to behavior change while higher levels of autonomous motivation improve the likelihood of behavior modification. Methods This study assessed the outcomes of two internet behavioral weight loss interventions and assessed the effect of baseline motivation levels on program success. Eighty females (M (SD age 48.7 (10.6 years; BMI 32.0 (3.7 kg/m2; 91% Caucasian were randomized to one of two groups, a standard group or a motivation-enhanced group. Both received a 16-week internet behavioral weight loss program and attended an initial and a four-week group session. Weight and motivation were measured at baseline, four and 16 weeks. Hierarchical regression analysis was conducted to test for moderation. Results There was significant weight loss at 16-weeks in both groups (p p = 0.57 (standard group 3.4 (3.6 kg; motivation-enhanced group 3.9 (3.4 kg. Further analysis was conducted to examine predictors of weight loss. Baseline controlled motivation level was negatively correlated with weight loss in the entire sample (r = -0.30; p = 0.01. Statistical analysis revealed an interaction between study group assignment and baseline level of controlled motivation. Weight loss was not predicted by baseline level of controlled motivation in the motivation-enhanced group, but was significantly predicted by controlled motivation in the standard group. Baseline autonomous motivation did not predict weight change in either group. Conclusions This research found that, in participants with high levels of baseline controlled motivation

  5. THE EFFECTS OF TAI CHI CHUAN COMBINED WITH VIBRATION TRAINING ON BALANCE CONTROL AND LOWER EXTREMITY MUSCLE POWER

    Directory of Open Access Journals (Sweden)

    Pao-Hung Chung

    2013-03-01

    Full Text Available The aim of this study was to determine whether performing Tai Chi Chuan on a customized vibration platform could enhance balance control and lower extremity muscle power more efficiently than Tai Chi Chuan alone in an untrained young population. Forty-eight healthy young adults were randomly assigned to the following three groups: a Tai Chi Chuan combined with vibration training group (TCV, a Tai Chi Chuan group (TCC or a control group. The TCV group underwent 30 minutes of a reformed Tai Chi Chuan program on a customized vibration platform (32 Hz, 1 mm three times a week for eight weeks, whereas the TCC group was trained without vibration stimuli. A force platform was used to measure the moving area of a static single leg stance and the heights of two consecutive countermovement jumps. The activation of the knee extensor and flexor was also measured synchronously by surface electromyography in all tests. The results showed that the moving area in the TCV group was significantly decreased by 15.3%. The second jump height in the TCV group was significantly increased by 8.14%, and the activation of the knee extensor/flexor was significantly decreased in the first jump. In conclusion, Tai Chi Chuan combined with vibration training can more efficiently improve balance control, and the positive training effect on the lower extremity muscle power induced by vibration stimuli still remains significant because there is no cross-interaction between the two different types of training methods.

  6. Weighted approximation with varying weight

    CERN Document Server

    Totik, Vilmos

    1994-01-01

    A new construction is given for approximating a logarithmic potential by a discrete one. This yields a new approach to approximation with weighted polynomials of the form w"n"(" "= uppercase)P"n"(" "= uppercase). The new technique settles several open problems, and it leads to a simple proof for the strong asymptotics on some L p(uppercase) extremal problems on the real line with exponential weights, which, for the case p=2, are equivalent to power- type asymptotics for the leading coefficients of the corresponding orthogonal polynomials. The method is also modified toyield (in a sense) uniformly good approximation on the whole support. This allows one to deduce strong asymptotics in some L p(uppercase) extremal problems with varying weights. Applications are given, relating to fast decreasing polynomials, asymptotic behavior of orthogonal polynomials and multipoint Pade approximation. The approach is potential-theoretic, but the text is self-contained.

  7. Intrahospital weight and aerobic training in children with cystic fibrosis: a randomized controlled trial.

    Science.gov (United States)

    Santana Sosa, Elena; Groeneveld, Iris F; Gonzalez-Saiz, Laura; López-Mojares, Luis M; Villa-Asensi, José R; Barrio Gonzalez, María I; Fleck, Steven J; Pérez, Margarita; Lucia, Alejandro

    2012-01-01

    The purpose of our study was to assess the effects of an 8-wk intrahospital combined circuit weight and aerobic training program performed by children with cystic fibrosis (of low-moderate severity and stable clinical condition) on the following outcomes: cardiorespiratory fitness (VO2peak) and muscle strength (five-repetition maximum (5RM) bench press, 5RM leg press, and 5RM seated row) (primary outcomes) and pulmonary function (forced vital capacity, forced expiratory volume in 1 s), weight, body composition, functional mobility (Timed Up and Down Stairs and 3-m Timed Up and Go tests), and quality of life (secondary outcomes). We also determined the effects of a detraining period (4 wk) on the aforementioned outcomes. We performed a randomized controlled trial design. Eleven participants in each group (controls: 7 boys, age = 11 ± 3 yr, body mass index = 17.2 ± 0.8 kg · m(-2) (mean ± SEM); intervention: 6 boys, age = 10 ± 2 yr, body mass index = 18.4 ± 1.0 kg · m(-2)) started the study. Adherence to training averaged 95.1% ± 7.4%. We observed a significant group × time interaction effect (P = 0.036) for VO2peak. In the intervention group, VO2peak significantly increased with training by 3.9 mL · kg(-1) · min(-1) (95% confidence interval = 1.8-6.1 mL · kg(-1) · min(-1), P = 0.002), whereas it decreased during the detraining period (-3.4 mL · kg(-1) · min(-1), 95% confidence interval = -5.7 to -1.7 mL · kg(-1) · min(-1), P = 0.001). In contrast, no significant changes were observed during the study period within the control group. Although significant improvements were also observed after training for all 5RM strength tests (P 0.1 for after training vs detraining). We found no significant training benefits in any of the secondary outcomes. A short-term combined circuit weight and aerobic training program performed in a hospital setting induces significant benefits in the cardiorespiratory fitness and muscle strength of children with cystic fibrosis.

  8. An adaptive method with weight matrix as a function of the state to design the rotatory flexible system control law

    Science.gov (United States)

    Souza, Luiz C. G.; Bigot, P.

    2016-10-01

    One of the most well-known techniques of optimal control is the theory of Linear Quadratic Regulator (LQR). This method was originally applied only to linear systems but has been generalized for non-linear systems: the State Dependent Riccati Equation (SDRE) technique. One of the advantages of SDRE is that the weight matrix selection is the same as in LQR. The difference is that weights are not necessarily constant: they can be state dependent. Then, it gives an additional flexibility to design the control law. Many are applications of SDRE for simulation or real time control but generally SDRE weights are chosen constant so no advantage of this flexibility is taken. This work serves to show through simulation that state dependent weights matrix can improve SDRE control performance. The system is a non-linear flexible rotatory beam. In a brief first part SDRE theory will be explained and the non-linear model detailed. Then, influence of SDRE weight matrix associated with the state Q will be analyzed to get some insight in order to assume a state dependent law. Finally, these laws are tested and compared to constant weight matrix Q. Based on simulation results; one concludes showing the benefits of using an adaptive weight Q rather than a constant one.

  9. Multiple Iteration of Weight Updates for Least Mean Square Adaptive Filter in Active Noise Control Application

    Directory of Open Access Journals (Sweden)

    Mustafa Rahimie

    2017-01-01

    Full Text Available The method of least mean square (LMS is the commonly used algorithm in Adaptive filter due to its simplicity and robustness in implementation. In Active Noise Control application, a filtered reference signal is used prior to LMS algorithm to overcome the constraint on stability and convergence performance of the system due to the existence of the auxiliary path. This is known as Filtered-X LMS algorithm. In conventional Filtered-X LMS algorithm, each filter weight is updated once on every audio sample. This paper proposes the improved version of Filtered-X LMS algorithm with the use of multiple iteration of filter weight on every sample of audio signal. The proposed work uses field programmable gate arrays to realize real-time simulation on hardware for the noise signal of 500 Hz. Results from the real-time hardware simulations have shown much faster error convergence and better adaptation performance for different selections of learning constant μ, as compared with the conventional method.

  10. Research-to-policy translation for prevention of disordered weight and shape control behaviors: A case example targeting dietary supplements sold for weight loss and muscle building.

    Science.gov (United States)

    Austin, S Bryn; Yu, Kimberly; Tran, Alvin; Mayer, Beth

    2017-04-01

    New approaches to universal eating disorders prevention and interventions targeting macro-environmental change are greatly needed, and research-to-policy translation efforts hold promise for advancing both of these goals. This paper describes as a policy-translation case example an academic-community-government partnership of the Strategic Training Initiative for the Prevention of Eating Disorders, Multi-Service Eating Disorders Association, and the office of Massachusetts Representative Kay Khan, all based in Massachusetts, USA. The partnership's research-to-policy translation project focused on dietary supplements sold for weight loss and muscle building, which have been linked with serious injury and death in consumers. Youth and people of all ages with eating disorders and body dysmorphic disorder may be especially vulnerable to use these products due to deceptive promises of fast and safe weight loss and muscle gain. The research-to-policy translation project was informed by a triggers-to-action framework to establish the evidentiary base of harm to consumers, operationalize policy solutions to mitigate harm through legislation, and generate political will to support action through legislation introduced in the Massachusetts legislature to restrict sales of weight-loss and muscle-building dietary supplements. The paper concludes with lessons learned from this unique policy translation effort for the prevention of disordered weight and shape control behaviors and offers recommendations for next steps for the field to advance research and practice for universal, macro-environmentally targeted prevention. Copyright © 2016 Elsevier Ltd. All rights reserved.

  11. Exoskeleton control for lower-extremity assistance based on adaptive frequency oscillators: adaptation of muscle activation and movement frequency.

    Science.gov (United States)

    Aguirre-Ollinger, Gabriel

    2015-01-01

    In this article, we analyze a novel strategy for assisting the lower extremities based on adaptive frequency oscillators. Our aim is to use the control algorithm presented here as a building block for the control of powered lower-limb exoskeletons. The algorithm assists cyclic movements of the human extremities by synchronizing actuator torques with the estimated net torque exerted by the muscles. Synchronization is produced by a nonlinear dynamical system combining an adaptive frequency oscillator with a form of adaptive Fourier analysis. The system extracts, in real time, the fundamental frequency component of the net muscle torque acting on a specific joint. Said component, nearly sinusoidal in shape, is the basis for the assistive torque waveform delivered by the exoskeleton. The action of the exoskeleton can be interpreted as a virtual reduction in the mechanical impedance of the leg. We studied the ability of human subjects to adapt their muscle activation to the assistive torque. Ten subjects swung their extended leg while coupled to a stationary hip joint exoskeleton. The experiment yielded a significant decrease, with respect to unassisted movement, of the activation levels of an agonist/antagonist pair of muscles controlling the hip joint's motion, which suggests the exoskeleton control has potential for assisting human gait. A moderate increase in swing frequency was observed as well. We theorize that the increase in frequency can be explained by the impedance model of the assisted leg. Per this model, subjects adjust their swing frequency in order to control the amount of reduction in net muscle torque.

  12. Control strategies for active lower extremity prosthetics and orthotics: a review.

    Science.gov (United States)

    Tucker, Michael R; Olivier, Jeremy; Pagel, Anna; Bleuler, Hannes; Bouri, Mohamed; Lambercy, Olivier; Millán, José Del R; Riener, Robert; Vallery, Heike; Gassert, Roger

    2015-01-05

    : Technological advancements have led to the development of numerous wearable robotic devices for the physical assistance and restoration of human locomotion. While many challenges remain with respect to the mechanical design of such devices, it is at least equally challenging and important to develop strategies to control them in concert with the intentions of the user.This work reviews the state-of-the-art techniques for controlling portable active lower limb prosthetic and orthotic (P/O) devices in the context of locomotive activities of daily living (ADL), and considers how these can be interfaced with the user's sensory-motor control system. This review underscores the practical challenges and opportunities associated with P/O control, which can be used to accelerate future developments in this field. Furthermore, this work provides a classification scheme for the comparison of the various control strategies.As a novel contribution, a general framework for the control of portable gait-assistance devices is proposed. This framework accounts for the physical and informatic interactions between the controller, the user, the environment, and the mechanical device itself. Such a treatment of P/Os--not as independent devices, but as actors within an ecosystem--is suggested to be necessary to structure the next generation of intelligent and multifunctional controllers.Each element of the proposed framework is discussed with respect to the role that it plays in the assistance of locomotion, along with how its states can be sensed as inputs to the controller. The reviewed controllers are shown to fit within different levels of a hierarchical scheme, which loosely resembles the structure and functionality of the nominal human central nervous system (CNS). Active and passive safety mechanisms are considered to be central aspects underlying all of P/O design and control, and are shown to be critical for regulatory approval of such devices for real-world use.The works

  13. Eating disorders and disordered weight and shape control behaviors in sexual minority populations

    Science.gov (United States)

    Calzo, Jerel P.; Blashill, Aaron J.; Brown, Tiffany A.; Argenal, Russell L.

    2017-01-01

    Purpose of review This review summarized trends and key findings from empirical studies conducted between 2011–2017 regarding eating disorders and disordered weight and shape control behaviors among lesbian, gay, bisexual, and other sexual minority (i.e., non-heterosexual) populations. Recent findings Recent research has examined disparities through sociocultural and minority stress approaches. Sexual minorities continue to demonstrate higher rates of disordered eating; disparities are more pronounced among males. Emerging data indicates elevated risk for disordered eating pathology among sexual minorities who are transgender or ethnic minorities. Dissonance-based eating disorder prevention programs may hold promise for sexual minority males. Summary Continued research must examine the intersections of sexual orientation, gender, and ethnic identities, given emergent data that eating disorder risk may be most prominent among specific subgroups. More research is needed within sexual minorities across the lifespan. There are still a lack of eating disorder treatment and prevention studies for sexual minorities. PMID:28660475

  14. A novel antioxidant beverage for body weight control based on coffee silverskin.

    Science.gov (United States)

    Martinez-Saez, Nuria; Ullate, Mónica; Martin-Cabrejas, María A; Martorell, Patricia; Genovés, Salvador; Ramon, Daniel; del Castillo, María Dolores

    2014-05-01

    The present research aimed to add value to coffee silverskin by looking for new innovative applications. Formulation of novel beverages based on coffee silverskin for body fat reduction and body weight control was proposed. Conditions for beverage preparation were optimised. Data on chemical composition and sensorial quality of the new drink were acquired. Health benefits were evaluated in vitro and in vivo employing as animal model Caenorhabditis elegans. An antioxidant beverage containing physiological active concentrations of caffeine and chlorogenic acid for prevention body fat accumulation and possessing acceptable sensorial properties was obtained. Our findings support that the use of coffee silverskin for obtaining bioactive extract is an innovative way for revalorisation of coffee by-product.

  15. Modeling, Calibration and Control for Extreme-Precision MEMS Deformable Mirrors Project

    Data.gov (United States)

    National Aeronautics and Space Administration — Iris AO will develop electromechanical models and actuator calibration methods to enable open-loop control of MEMS deformable mirrors (DMs) with unprecedented...

  16. Active disturbance rejection control based human gait tracking for lower extremity rehabilitation exoskeleton.

    Science.gov (United States)

    Long, Yi; Du, Zhijiang; Cong, Lin; Wang, Weidong; Zhang, Zhiming; Dong, Wei

    2017-03-01

    This paper presents an active disturbance rejection control (ADRC) based strategy, which is applied to track the human gait trajectory for a lower limb rehabilitation exoskeleton. The desired human gait trajectory is derived from the Clinical Gait Analysis (CGA). In ADRC, the total external disturbance can be estimated by the extended state observer (ESO) and canceled by the designed control law. The observer bandwidth and the controller bandwidth are determined by the practical principles. We simulated the proposed methodology in MATLAB. The numerical simulation shows the tracking error comparison and the estimated errors of the extended state observer. Two experimental tests were carried out to prove the performance of the algorithm presented in this paper. The experiment results show that the proposed ADRC behaves a better performance than the regular proportional integral derivative (PID) controller. With the proposed ADRC, the rehabilitation system is capable of tracking the target gait more accurately.

  17. Control limitations from distributed sensing: theory and Extremely Large Telescope application

    OpenAIRE

    Sarlette, Alain; Sepulchre, Rodolphe

    2013-01-01

    We investigate performance bounds for feedback control of distributed plants where the controller can be centralized (i.e. it has access to measurements from the whole plant), but sensors only measure differences between neighboring subsystem outputs. Such "distributed sensing" can be a technological necessity in applications where system size exceeds accuracy requirements by many orders of magnitude. We formulate how distributed sensing generally limits feedback performance robust to measure...

  18. Hispanic maternal influences on daughters' unhealthy weight control behaviors: The role of maternal acculturation, adiposity, and body image disturbances.

    Science.gov (United States)

    Olvera, Norma; Matthews-Ewald, Molly R; McCarley, Kendall; Scherer, Rhonda; Posada, Alexandria

    2016-12-01

    This study examined whether maternal adiposity, acculturation, and perceived-ideal body size discrepancy for daughters were associated with daughters' engagement in unhealthy weight control behaviors. A total of 97 Hispanic mother-daughter dyads completed surveys, rated a figure scale, and had their height, weight, and adiposity assessed. Mothers (Mage=39.00, SD=6.20 years) selected larger ideal body sizes for their daughters (Mage=11.12, SD=1.53 years) than their daughters selected for themselves. Mothers had a smaller difference between their perception of their daughters' body size and ideal body size compared to the difference between their daughters' selection of their perceived and ideal body size. More acculturated mothers and those mothers with larger waist-to-hip ratios were more likely to have daughters who engaged in unhealthy weight control behaviors. These findings highlight the relevant role that maternal acculturation and adiposity may have in influencing daughters' unhealthy weight control behaviors.

  19. Independent genetic control of maize (Zea mays L.) kernel weight determination and its phenotypic plasticity.

    Science.gov (United States)

    Alvarez Prado, Santiago; Sadras, Víctor O; Borrás, Lucas

    2014-08-01

    Maize kernel weight (KW) is associated with the duration of the grain-filling period (GFD) and the rate of kernel biomass accumulation (KGR). It is also related to the dynamics of water and hence is physiologically linked to the maximum kernel water content (MWC), kernel desiccation rate (KDR), and moisture concentration at physiological maturity (MCPM). This work proposed that principles of phenotypic plasticity can help to consolidated the understanding of the environmental modulation and genetic control of these traits. For that purpose, a maize population of 245 recombinant inbred lines (RILs) was grown under different environmental conditions. Trait plasticity was calculated as the ratio of the variance of each RIL to the overall phenotypic variance of the population of RILs. This work found a hierarchy of plasticities: KDR ≈ GFD > MCPM > KGR > KW > MWC. There was no phenotypic and genetic correlation between traits per se and trait plasticities. MWC, the trait with the lowest plasticity, was the exception because common quantitative trait loci were found for the trait and its plasticity. Independent genetic control of a trait per se and genetic control of its plasticity is a condition for the independent evolution of traits and their plasticities. This allows breeders potentially to select for high or low plasticity in combination with high or low values of economically relevant traits.

  20. Study of weighted space deconvolution algorithm in computer controlled optical surfacing formation

    Institute of Scientific and Technical Information of China (English)

    Hongyu Li; Wei Zhang; Guoyu Yu

    2009-01-01

    Theoretical and experimental research on the deconvolution algorithm of dwell time in the technology of computer controlled optical surfacing (CCOS) formation is made to get an ultra-smooth surface of space optical element. Based on the Preston equation, the convolution model of CCOS is deduced. Considering the morbidity problem of deconvolution algorithm and the actual situation of CCOS technology, the weighting spatial deconvolution algorithm is presented based on the non-periodic matrix model, which avoids solving morbidity resulting from the noise induced by measurement error. The discrete convolution equation is solved using conjugate gradient iterative method and the workload of iterative calculation in spatial domain is reduced effectively. Considering the edge effect of convolution algorithm, the method adopts a marginal factor to control the edge precision and attains a good effect. The simulated processing test shows that the convergence ratio of processed surface shape error reaches 80%. This algorithm is further verified through an experiment on a numerical control bonnet polishing machine, and an ultra-smooth glass surface with the root-mean-square (RMS) error of 0.0088 μm is achieved. The simulation and experimental results indicate that this algorithm is steady, convergent, and precise, and it can satisfy the solving requirement of actual dwell time.

  1. [Weight control behaviors in dieting adolescent girls and their relation to body dissatisfaction and obsession with thinness].

    Science.gov (United States)

    Contreras, M Liliana A; Morán, Javier K; Frez, Scarlett H; Lagos, Carola O; Marín, María Paz F; de los Ángeles Pinto B, María; Suzarte, Érika A

    2015-01-01

    Obsession with thinness and body dissatisfaction can lead adolescents to follow unsupervised diets, which could result in risky weight control behaviors such as fasting, vomiting, use of diuretics and laxatives. The aim of the current study is to examine weight control behaviors in dieting adolescents and relate them to body dissatisfaction (BD) and obsession with thinness (OT). A cross-sectional study was conducted on 439 adolescents from Valparaiso public schools to investigate risky weight control behaviors due to BD and OT scales from the Eating Disorders Inventory-2 (EDI-2), comparing restrained eaters and non-restrained eaters. A total of 43% adolescents had followed a weight loss diet without medical supervision. The dieters had higher BD and OT values. Moderate to severe food restriction, based on expert judgment, was observed in 29.6%, and differences in the presence and severity of purging behaviors were found between the 2 groups. One third of the adolescents studied followed diets without professional supervision and had higher BD and OT values, as well as risky weight control behaviors. Overweight and obese adolescents followed more restrictive diets and developed riskier weight control behaviors. Copyright © 2015. Publicado por Elsevier España, S.L.U.

  2. 103例超未成熟儿及超低出生体重儿转归及影响因素分析%Outcome and influencing factors of 103 cases of extremely premature infant and extremely low birth weight infants

    Institute of Scientific and Technical Information of China (English)

    王晓磊; 梅花; 刘春枝; 张亚昱; 刘春丽; 宋丹; 张钰恒

    2016-01-01

    目的 总结超未成熟儿及超低出生体重儿发生的原因、相关影响因素及转归情况.方法 分析内蒙古医科大学附属医院2009年1月至2015年12月NICU收治的符合条件的103例超低出生体重儿及超未成熟儿的临床资料,包括母孕期病史、新生儿出生时情况、诊治经过及预后.结果 103例患儿存活67例,死亡36例,存活率65.0% (67/103).妊娠高血压综合征、感染、胎膜早破等为发生超未成熟和超低出生体重儿的主要因素,影响两者的转归因素包括胎龄、性别、出生体重、肺出血、支气管肺发育不良、坏死性小肠结肠炎(P<0.05).长期住院的存活患儿后期易并发贫血.死亡直接原因前4位包括肺出血、呼吸窘迫综合征、新生儿肺炎及坏死性小肠结肠炎.结论 加强高危妊娠监测管理,预防早产,加强NICU超未成熟儿及超低出生体重儿的监护管理,及早发现、及早处理各种并发症,防止医院感染发生,是提高两者存活率,改善生活质量的根本措施.%Objective To summarize the causes,related factors and outcome of extremely premature infants and extremely low birth weight infants.Methods One hundred and three cases of extremely premature infants and extremely low birth weight infants were admired to First Affiliated Hospital of Inner Mongolia Medical University between January 2009 and December 2015.The study was performed to analyze the clinical data of the 103 cases,included history of pregnancy,birth situation,treatment and prognosis.Results In these 103 cases,67 infants survived,36 infants died.The survival rate was 65.0% (67/103).The extremely premature infants and extremely low birth weight infants were mainly associated with pregnancy-induced hypertension,infection,premature rupture of membranes.Factors that could affect the outcome of these cases included gestational age,sex,birth weight,pulmonary hemorrhage,bronchopulmonary dysplasia and necrotizing

  3. Analysis of early respiratory complications on extremely low and very low birth weight infants%超低和极低出生体重儿早期呼吸系统并发症分析

    Institute of Scientific and Technical Information of China (English)

    余华娟

    2013-01-01

    目的探讨超低和极低出生体重儿早期呼吸系统并发症的发生情况。方法对2010年3月~2012年12月本院出生的129例超低和极低出生体重儿早期呼吸系统并发症进行临床分析。结果新生儿呼吸窘迫综合征(NRDS),呼吸暂停,肺部感染,气漏,支气管肺发育不良(BPD)3组间比较,差异有统计学意义(P<0.05),其中<1000 g组发生率最高,1250~1499 g组发生率最低。3组痊愈率比较,差异有统计学意义(P<0.05)。结论对超低和极低出生体重儿早期呼吸系统并发症进行密切监护和针对治疗,可提高患儿的成活率,提高生存质量。%Objective To investigate the occurrence of early respiratory complications on extremely low and very low birth weight infants. Methods Early respiratory complications of 129 cases with extremely low and very low birth weight infants born in our hospital from March 2010 to December 2012 were analyzed. Results There were significant differences in NRDS,apnea,pulmonary infection,gas leakage and BPD among the three groups(P<0.05).The incidence of the group with birth weight less than 1000 g was the highest,while the incidence of the group with birth weight ranged from 1250 g to 1499 g was the lowest.There was significant difference in the cure rate among the three groups(P<0.05). Concluson Close monitoring and corresponding treatment of early respiratory complications on extremely low and very low birth weight infants can improve the survival rate and life quality of infants.

  4. A Multifactorial Weight Reduction Programme for Children with Overweight and Asthma : A Randomized Controlled Trial

    NARCIS (Netherlands)

    Willeboordse, Maartje; Kant, Kim D G van de; Tan, Frans E S; Mulkens, Sandra; Schellings, Julia; Crijns, Yvonne; Ploeg, Liesbeth van der; van Schayck, Constant P; Dompeling, Edward

    2016-01-01

    BACKGROUND: There is increasing evidence that obesity is related to asthma development and severity. However, it is largely unknown whether weight reduction can influence asthma management, especially in children. OBJECTIVE: To determine the effects of a multifactorial weight reduction intervention

  5. Control of blood glucose in type 2 diabetes without weight loss by modification of diet composition

    Directory of Open Access Journals (Sweden)

    Gannon Mary C

    2006-03-01

    Full Text Available Abstract Background Over the past several years our research group has taken a systematic, comprehensive approach to determining the effects on body function (hormonal and non-hormonal of varying the amounts and types of proteins, carbohydrates and fats in the diet. We have been particularly interested in the dietary management of type 2 diabetes. Our objective has been to develop a diet for people with type 2 diabetes that does not require weight loss, oral agents, or insulin, but that still controls the blood glucose concentration. Our overall goal is to enable the person with type 2 diabetes to control their blood glucose by adjustment in the composition rather than the amount of food in their diet. Methods This paper is a brief summary and review of our recent diet-related research, and the rationale used in the development of diets that potentially are useful in the treatment of diabetes. Results We determined that, of the carbohydrates present in the diet, absorbed glucose is largely responsible for the food-induced increase in blood glucose concentration. We also determined that dietary protein increases insulin secretion and lowers blood glucose. Fat does not significantly affect blood glucose, but can affect insulin secretion and modify the absorption of carbohydrates. Based on these data, we tested the efficacy of diets with various protein:carbohydrate:fat ratios for 5 weeks on blood glucose control in people with untreated type 2 diabetes. The results were compared to those obtained in the same subjects after 5 weeks on a control diet with a protein:carbohydrate:fat ratio of 15:55:30. A 30:40:30 ratio diet resulted in a moderate but significant decrease in 24-hour integrated glucose area and % total glycohemoglobin (%tGHb. A 30:20:50 ratio diet resulted in a 38% decrease in 24-hour glucose area, a reduction in fasting glucose to near normal and a decrease in %tGHb from 9.8% to 7.6%. The response to a 30:30:40 ratio diet was similar

  6. Brain functional plasticity associated with the emergence of expertise in extreme language control.

    Science.gov (United States)

    Hervais-Adelman, Alexis; Moser-Mercer, Barbara; Golestani, Narly

    2015-07-01

    We used functional magnetic resonance imaging (fMRI) to longitudinally examine brain plasticity arising from long-term, intensive simultaneous interpretation training. Simultaneous interpretation is a bilingual task with heavy executive control demands. We compared brain responses observed during simultaneous interpretation with those observed during simultaneous speech repetition (shadowing) in a group of trainee simultaneous interpreters, at the beginning and at the end of their professional training program. Age, sex and language-proficiency matched controls were scanned at similar intervals. Using multivariate pattern classification, we found distributed patterns of changes in functional responses from the first to second scan that distinguished the interpreters from the controls. We also found reduced recruitment of the right caudate nucleus during simultaneous interpretation as a result of training. Such practice-related change is consistent with decreased demands on multilingual language control as the task becomes more automatized with practice. These results demonstrate the impact of simultaneous interpretation training on the brain functional response in a cerebral structure that is not specifically linguistic, but that is known to be involved in learning, in motor control, and in a variety of domain-general executive functions. Along with results of recent studies showing functional and structural adaptations in the caudate nuclei of experts in a broad range of domains, our results underline the importance of this structure as a central node in expertise-related networks. Copyright © 2015 Elsevier Inc. All rights reserved.

  7. Dynamic analysis and control of mirror segment actuators for the European Extremely Large Telescope

    Science.gov (United States)

    Witvoet, Gert; den Breeje, Remco; Nijenhuis, Jan; Hazelebach, René; Doelman, Niek

    2015-01-01

    Segmented primary mirror telescopes require dedicated piston-tip-tilt actuators for optimal optical performance. Netherlands Organisation for Applied Scientific Research (TNO) has developed various prototypes of such actuators, in particular for the E-ELT. This paper presents the dynamics analysis and feedback control results for a specific two-stage prototype. First, the dynamics of the actuator in interconnection with the to-be-positioned mass has been analyzed, both using frequency response measurements and first principles modeling, resulting in a detailed understanding of the dynamic behavior of the system. Next, feedback controllers for both the fine and the coarse stage have been designed and implemented. Finally, the feedback-controlled actuator has been subjected to a realistic tracking experiment; the achieved results have demonstrated that the TNO actuator is able to suppress wind force disturbances and ground vibrations with more than a factor 103, down to 1.4 nm root mean square, which is compliant with the requirements.

  8. Body mass index as a prognostic factor for fracturing of the proximal extremity of the femur: a case-control study,

    Directory of Open Access Journals (Sweden)

    Renato Cavanus Pagani

    2014-10-01

    Full Text Available Objectives:To compare the body mass index (BMI of patients with fractures in the proximal extremity of the femur with the BMI of patients without any previous history of fractures.Methods:We investigated patients of both sexes, aged 65 years or over, who were admitted to Hospital Independência, Hospital Beneficência Portuguesa or ULBRA University Hospital, between December 2007 and December 2010, with histories of low-energy trauma such as falling from a standingposition. These individuals were compared with patients of the same age but without any history of fracturing of the proximal extremity of the femur (n = 89, who were attended at the geriatrics outpatient clinic of the Sociedade Porto-Alegrense de Auxílio aos Necessitados (SPAAN.Results:The age group of the patients with fractures in the proximal extremity of the femur ranged from 65 to 96 years (mean: 77.58. The main type of fracture was trochanteric (47; 62.2%, followed by femoral neck fractures (27; 36%. Among the patients who presented on fracturing the proximal extremity of the femur, 12% had low weight, 62.7% normal weight, 24% overweight, and 1.3% obesity. Among the patients without any history of fractures, 5.6% presented low weight, 43.8% normal weight, 33.7% overweight, and 9.8% obesity. It was observed that the patients with fractures in the proximal extremity of the femur (n = 75 presented a mean BMI of 22.6, while the patients without fractures presented a mean BMI of 25.5.Conclusion:The patients in the group with fractures were significantly taller than those in the group without fractures and presented significantly lower BMI than those in the group without fractures.

  9. Body mass index as a prognostic factor for fracturing of the proximal extremity of the femur: a case–control study☆☆☆

    Science.gov (United States)

    Pagani, Renato Cavanus; Kunz, Rodrigo Ernesto; Girardi, Ricardo; Guerra, Marcelo

    2014-01-01

    Objectives To compare the body mass index (BMI) of patients with fractures in the proximal extremity of the femur with the BMI of patients without any previous history of fractures. Methods We investigated patients of both sexes, aged 65 years or over, who were admitted to Hospital Independência, Hospital Beneficência Portuguesa or ULBRA University Hospital, between December 2007 and December 2010, with histories of low-energy trauma such as falling from a standing position. These individuals were compared with patients of the same age but without any history of fracturing of the proximal extremity of the femur (n = 89), who were attended at the geriatrics outpatient clinic of the Sociedade Porto-Alegrense de Auxílio aos Necessitados (SPAAN). Results The age group of the patients with fractures in the proximal extremity of the femur ranged from 65 to 96 years (mean: 77.58). The main type of fracture was trochanteric (47; 62.2%), followed by femoral neck fractures (27; 36%). Among the patients who presented on fracturing the proximal extremity of the femur, 12% had low weight, 62.7% normal weight, 24% overweight, and 1.3% obesity. Among the patients without any history of fractures, 5.6% presented low weight, 43.8% normal weight, 33.7% overweight, and 9.8% obesity. It was observed that the patients with fractures in the proximal extremity of the femur (n = 75) presented a mean BMI of 22.6, while the patients without fractures presented a mean BMI of 25.5. Conclusion The patients in the group with fractures were significantly taller than those in the group without fractures and presented significantly lower BMI than those in the group without fractures. PMID:26229845

  10. Motor Control of the Lower Extremity Musculature in Children with Cerebral Palsy

    Science.gov (United States)

    Arpin, David J.; Stuberg, Wayne; Stergiou, Nicholas; Kurz, Max J.

    2013-01-01

    The aim of this investigation was to quantify the differences in torque steadiness and variability of the muscular control in children with cerebral palsy (CP) and typically developing (TD) children. Fifteen children with CP (age = 14.2 [plus or minus] 0.7 years) that had a Gross Motor Function Classification System (GMFCS) score of I-III and 15…

  11. High performance control of mirror segment actuators for the European Extremely Large Telescope

    NARCIS (Netherlands)

    Witvoet, G.; Breeje, R. de; Nijenhuis, J.R.; Hazelebach, R.L.M.; Doelman, N.J.

    2014-01-01

    Segmented primary mirror telescopes require dedicated piston-tip-tilt actuators for optimal optical performance. TNO has developed various prototypes of such actuators, in particular for the E-ELT. In this paper the control results of a specific two-stage prototype will be presented.

  12. Transcriptional control of anthocyanin biosynthetic genes in extreme phenotypes for berry pigmentation of naturally occurring grapevines

    Directory of Open Access Journals (Sweden)

    Castellarin Simone D

    2007-08-01

    Full Text Available Abstract Background Fruit coloration of red-skinned grapevines is mainly due to anthocyanin pigments. We analysed a panel of nine cultivars that included extreme phenotypes for berry colour, ranging from green (absence of anthocyanins to red, purple, violet and blue. Expression of six genes of the anthocyanin pathway coding for flavanone-hydroxylase (F3H, flavonoid 3'-hydroxylase (F3'H, flavonoid 3',5'-hydroxylase (F3'5'H, UDP-glucose:flavonoid-3-O-glucosyltransferase (UFGT, glutathione-S-transferase (GST, O-methyltransferase (OMT and four transcription factors (MybA, MybB, MybC, MybD was analysed by quantitative RT-PCR at four developmental stages from before the onset of ripening until full maturity and compared to anthocyanin metabolites. Results Total anthocyanin content at full maturity correlated well with the cumulative expression of F3H, UFGT and GST throughout ripening. Transcripts of the last two genes were absent in the green-skinned cultivar 'Sauvignonasse', also known as 'Tocai friulano', and were at least 10-fold less abundant in pale red cultivars, such as 'Pinot gris' and 'Gewürztraminer', compared to fully coloured cultivars. Predominance of tri-hydroxylated anthocyanins (delphinidin, petunidin and malvidin in cultivars bearing dark berries with violet and blue hue was associated with higher ratios of F3'5'H/F3'H transcription, compared to red-skinned cultivars. Higher levels of OMT transcripts were observed in berries of cultivars that accumulated methoxylated forms of anthocyanins more abundantly than non-methoxylated forms. Conclusion Colour variation of the grape berry conforms to a peculiar pattern of genotype-specific expression of the whole set of anthocyanin genes in a direct transcript-metabolite-phenotype relationship. Cumulative mRNA levels of the structural genes and their relative abundance throughout ripening explained per se the final phenotype for anthocyanin content, anthocyanin composition, colour intensity

  13. Obesity: a systematic review on parental involvement in long-term European childhood weight control interventions with a nutritional focus.

    Science.gov (United States)

    van der Kruk, J J; Kortekaas, F; Lucas, C; Jager-Wittenaar, H

    2013-09-01

    In Europe, about 20% of children are overweight. Focus on parental responsibility is an effective method in weight control interventions in children. In this systematic review we describe the intensity of parental involvement and behaviour change aimed at parents in long-term European childhood weight control interventions. We include European Union studies targeting parents in order to improve children's weight status in multi-component (parental, behaviour change and nutrition) health promotion or lifestyle interventions. The included studies have at least one objectively measured anthropometric outcome in the weight status of the child. Parental involvement was described and categorized based on the intensity of parental involvement and coded using a validated behaviour change taxonomy specific to childhood obesity. Twenty-four studies were analysed. In effective long-term treatment studies, medium and high intensity parental involvement were identified most frequently; whereas in prevention studies low intensity parental involvement was identified most frequently. Parenting skills, generic and specific to lifestyle behaviour, scored frequently in effective weight control interventions. To list parental skills in generic and specific to lifestyle, descriptions of the included studies were summarized. We conclude that intensity of parental involvement and behaviour change techniques are important issues in the effectiveness of long-term childhood weight control interventions. © 2013 The Authors. obesity reviews © 2013 International Association for the Study of Obesity.

  14. A review on botanical species and chemical compounds with appetite suppressing properties for body weight control.

    Science.gov (United States)

    Astell, Katie J; Mathai, Michael L; Su, Xiao Q

    2013-09-01

    As obesity has reached epidemic proportions, the management of this global disease is of clinical importance. The availability and popularity of natural dietary supplements for the treatment of obesity has risen dramatically in recent years. The purpose of this paper was to review the effect of commonly available over the counter plant-derived supplements used to suppress appetite for obesity control and management. The data were obtained from the electronic databases PubMed, SpringerLink, Google Scholar, ScienceDirect, and MEDLINE with full text (via EBSCOHost) and the databases were accessed during late 2012 - early January 2013. The botanical species discussed in this review include Camellia sinensis, Caralluma fimbriata, Citrus aurantium, Coleus forskohlii, Garcinia cambogia and Phaseolus vulgaris. This review found that many botanical species including crude extracts and isolated compounds from plants have been shown to provide potentially promising therapeutic effects including appetite control and weight loss. However, many of these crude extracts and compounds need to be further investigated to define the magnitude of the effects, optimal dosage, mechanisms of action, long term safety, and potential side effects.

  15. Beneficial effect of sulphate-bicarbonate-calcium water on gallstone risk and weight control

    Institute of Scientific and Technical Information of China (English)

    Stefano Ginanni Corradini; Edoardo Poli; Adriano De Santis; Aldo Roda; Carolina Colliva; Patrizia Simoni; Adolfo Francesco Attili; Flaminia Ferri; Michela Mordenti; Luigi Iuliano; Maria Siciliano; Maria Antonella Burza; Bruno Sordi; Barbara Caciotti; Maria Pacini

    2012-01-01

    AIM:To investigate the effect of drinking sulphate-bicarbonate-calcium thermal water (TW) on risk factors for atherosclerosis and cholesterol gallstone disease.METHODS:Postmenopausal women with functional dyspepsia and/or constipation underwent a 12 d cycle of thermal (n =20) or tap (n =20) water controlled drinking.Gallbladder fasting volume at ultrasound,blood vitamin E,oxysterols (7-β-hydroxycholesterol.and 7-ketocholesterol),bile acid (BA),triglycerides,total/low density lipoprotein and high density lipoprotein cholesterol were measured at baseline and at the end of the study.Food consumption,stool frequency and body weight were recorded daily.RESULTS:Blood lipids,oxysterols and vitamin E were not affected by either thermal or tap water consumption.Fasting gallbladder volume was significantly (P <0.005) smaller at the end of the study than at baseline in the TW (15.7 ± 1.1 mL vs 20.1 ± 1.7 mL) but not in the tap water group (19.0 ± 1.4 mL vs 19.4 ± 1.5 mL).Total serum BA concentration was significantly (P <0.05) higher at the end of the study than at baseline in the TW (5.83-1.24 μmol vs 4.25 ± 1.00 μmol) but not in the tap water group (3.41 ± 0.46 μmol vs 2.91 ± 0.56 μmol).The increased BA concentration after TW consumption was mainly accounted for by glycochenodeoxycholic acid.The number of pasta (P < 0.001),meat (P < 0.001) and vegetable (P < 0.005) portions consumed during the study and of bowel movements per day (P < 0.05) were significantly higher in the TW than in the tap water group.Body weight did not change at the end of the study as compared to baseline in both groups.CONCLUSION:Sulphate-bicarbonate-calcium water consumption has a positive effect on lithogenic risk and intestinal transit and allows maintenance of a stable body weight despite a high food intake.

  16. Beneficial effect of sulphate-bicarbonate-calcium water on gallstone risk and weight control

    Science.gov (United States)

    Corradini, Stefano Ginanni; Ferri, Flaminia; Mordenti, Michela; Iuliano, Luigi; Siciliano, Maria; Burza, Maria Antonella; Sordi, Bruno; Caciotti, Barbara; Pacini, Maria; Poli, Edoardo; Santis, Adriano De; Roda, Aldo; Colliva, Carolina; Simoni, Patrizia; Attili, Adolfo Francesco

    2012-01-01

    AIM: To investigate the effect of drinking sulphate-bicarbonate-calcium thermal water (TW) on risk factors for atherosclerosis and cholesterol gallstone disease. METHODS: Postmenopausal women with functional dyspepsia and/or constipation underwent a 12 d cycle of thermal (n = 20) or tap (n = 20) water controlled drinking. Gallbladder fasting volume at ultrasound, blood vitamin E, oxysterols (7-β-hydroxycholesterol and 7-ketocholesterol), bile acid (BA), triglycerides, total/low density lipoprotein and high density lipoprotein cholesterol were measured at baseline and at the end of the study. Food consumption, stool frequency and body weight were recorded daily. RESULTS: Blood lipids, oxysterols and vitamin E were not affected by either thermal or tap water consumption. Fasting gallbladder volume was significantly (P < 0.005) smaller at the end of the study than at baseline in the TW (15.7 ± 1.1 mL vs 20.1 ± 1.7 mL) but not in the tap water group (19.0 ± 1.4 mL vs 19.4 ± 1.5 mL). Total serum BA concentration was significantly (P < 0.05) higher at the end of the study than at baseline in the TW (5.83 ± 1.24 μmol vs 4.25 ± 1.00 μmol) but not in the tap water group (3.41 ± 0.46 μmol vs 2.91 ± 0.56 μmol). The increased BA concentration after TW consumption was mainly accounted for by glycochenodeoxycholic acid. The number of pasta (P < 0.001), meat (P < 0.001) and vegetable (P < 0.005) portions consumed during the study and of bowel movements per day (P < 0.05) were significantly higher in the TW than in the tap water group. Body weight did not change at the end of the study as compared to baseline in both groups. CONCLUSION: Sulphate-bicarbonate-calcium water consumption has a positive effect on lithogenic risk and intestinal transit and allows maintenance of a stable body weight despite a high food intake. PMID:22408352

  17. Molecular weight controllable degradation of Laminaria japonica polysaccharides and its antioxidant properties

    Science.gov (United States)

    Zha, Shenghua; Zhao, Qingsheng; Zhao, Bing; Ouyang, Jie; Mo, Jianling; Chen, Jinjin; Cao, Lili; Zhang, Hong

    2016-08-01

    In this study, molecular weight controllable degradation of algal Laminaria japonica polysaccharides (LPS) was investigated by ultrasound combined with hydrogen peroxide. Three main factors, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C) were chosen for optimizing parameters by employing three-factors, three-levels BBD. The influence of degradation on structure change and antioxidant activities was also investigated. A second-order polynomial equation including molecular weight (Y) of Laminaria japonica polysaccharides and each variable parameter, i.e., ultrasonic power (A), ultrasonic time (B), and H2O2 concentration (C), was established: Y=20718.67-4273.13 A-4000.38 B-1438.75 C+2333.25 AB+1511.00 AC+873.00 BC+2838.29 A 2 + 2490.79 B 2+873.04 C 2. The equation regression coefficient value ( R 2 = 0.969) indicated that this equation was valid. The value of the adjusted determination coefficient (adjusted R 2 = 0.914) also confirmed that the model was highly significant. The results of selected experimental degradation conditions matched with the predicted value. FT-IR spectra revealed that the structures of LPS before and after degradation were not significantly changed. Antioxidant activities of LPS revealed that low Mws possessed stronger inhibitory than the original polysaccharides. The scavenging effects on superoxide radicals was the highest when IC50 of crude LPS was 4.92 mg mL-1 and IC50 of Mw 18.576 KDa was 1.02 mg mL-1, which was fourfold higher than initial polysaccharide.

  18. Dynamic analysis and control of mirror segment actuators for the European Extremely Large Telescope

    OpenAIRE

    Witvoet, G.; Breeje, R. den; Nijenhuis, J.R.; Hazelebach, R.L.M.; Doelman, N.J.

    2014-01-01

    Segmented primary mirror telescopes require dedicated piston-tip-tilt actuators for optimal optical performance. Netherlands Organisation for Applied Scientific Research (TNO) has developed various prototypes of such actuators, in particular for the E-ELT. This paper presents the dynamics analysis and feedback control results for a specific two-stage prototype. First, the dynamics of the actuator in interconnection with the to-be-positioned mass has been analyzed, both using frequency respons...

  19. Whey Protein Supplementation Enhances Body Fat and Weight Loss in Women Long After Bariatric Surgery: a Randomized Controlled Trial.

    Science.gov (United States)

    Lopes Gomes, Daniela; Moehlecke, Milene; Lopes da Silva, Fernanda Bassan; Dutra, Eliane Said; D'Agord Schaan, Beatriz; Baiocchi de Carvalho, Kenia Mara

    2017-02-01

    The ideal nutritional approach for weight regain after bariatric surgery remains unclear. The objective of this study is to assess the effect of whey protein supplementation on weight loss and body composition of women who regained weight 24 or more months after bariatric surgery. This is a 16-week open-label, parallel-group, randomized controlled trial of women who regained at least 5 % of their lowest postoperative weight after a Roux-en-Y gastric bypass (RYGB). A total of 34 participants were treated with hypocaloric diet and randomized (1:1) to receive or not supplementation with whey protein, 0.5 g/kg of the ideal body weight. The primary outcomes were changes in body weight, fat free mass (FFM), and fat mass (FM), evaluated by tetrapolar bioelectrical impedance analysis (BIA). Secondary outcomes included resting energy expenditure, blood glucose, lipids, adiponectin, interleukin 6 (IL-6), and cholecystokinin levels. Statistical analyses included generalized estimating equations adjusted for age and physical activity. Fifteen patients in each group were evaluated: mean age was 45 ± 11 years, body mass index (BMI) was 35.7 ± 5.2 kg/m(2), and time since surgery was 69 ± 23 months. Protein intake during follow-up increased by approximately 75 % in the intervention group (p = 0.01). The intervention group presented more body weight loss (1.86 kg, p = 0.017), accounted for FM loss (2.78, p = 0.021) and no change in FFM, as compared to controls (gain of 0.42 kg of body weight and 0.6 kg of FM). No differences in secondary outcomes were observed between groups. Whey protein supplementation promoted body weight and FM loss in women with long-term weight regain following RYGB.

  20. A nudge in a healthier direction: How environmental cues help restrained eaters pursue their weight-control goal.

    Science.gov (United States)

    Stämpfli, Aline E; Stöckli, Sabrina; Brunner, Thomas A

    2017-03-01

    Losing weight is a goal for many people, but it is hard to pursue. However, dieting cues in the environment hold promise for improving individuals' eating behavior. For example, exposure to thin, human-like sculptures by the artist Alberto Giacometti has been found to promote healthy snack choices at a vending machine. Whether health- or weight-related processes drive such effects has not yet been determined. However, a detailed understanding of the content-related drivers of environmental cues' effects provides the first indications regarding a cue's possible use. Therefore, two laboratory studies were conducted. They examined the Giacometti sculptures' effects on unhealthy and healthy food intake (Study 1) and on the completion of weight- and health-related fragmented words (Study 2). Study 1 indicated that the sculptures are weight-related by showing that they reduced food intake independent of food healthiness. Furthermore, the "Giacometti effect" was moderated by restrained eating. Restrained eaters, who are known for their weight-control goal, ate less after having been exposed to the thin sculptures. The results of Study 2 pointed in the same direction. Restrained eaters completed more weight-related words after being exposed to the sculptures. Overall, these studies suggest that the thin sculptures are primarily weight-related cues and particularly helpful for restrained eaters. Environmental weight-control cues such as the Giacometti sculptures could act as a counterforce to our obesogenic environment and help restrained eaters pursue their weight-control goal. In this way, they could nudge food decisions in a healthier direction.

  1. Effect of upper extremity proprioceptive neuromuscular facilitation combined with elastic resistance bands on respiratory muscle strength: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Guilherme P. T. Areas

    2013-12-01

    Full Text Available BACKGROUND: Elastic resistance bands (ERB combined with proprioceptive neuromuscular facilitation (PNF are often used in resistance muscle training programs, which have potential effects on peripheral muscle strength. However, the effects of the combination of ERB and PNF on respiratory muscle strength warrant further investigation. OBJECTIVES: The assessment of the effects of PNF combined with ERB on respiratory muscle strength. METHOD: Twenty healthy, right-handed females were included. Subjects were randomized to either the resistance training program group (TG, n=10 or the control group (CG, n=10. Maximal expiratory pressure (MEP and inspiratory pressure (MIP were measured before and after four weeks of an upper extremity resistance training program. The training protocol consisted of upper extremity PNF combined with ERB, with resistance selected from 1 repetition maximum protocol. RESULTS: PNF combined with ERB showed significant increases in MIP and MEP (p<0.05. In addition, there were significant differences between the TG and CG regarding ∆MIP (p=0.01 and ∆MEP (p=0.04. CONCLUSIONS: PNF combined with ERB can have a positive impact on respiratory muscle strength. These results may be useful with respect to cardiopulmonary chronic diseases that are associated with reduced respiratory muscle strength.

  2. Contralaterally Controlled Functional Electrical Stimulation for Upper Extremity Hemiplegia: An Early-Phase Randomized Clinical Trial in Subacute Stroke Patients

    Science.gov (United States)

    Knutson, Jayme S.; Harley, Mary Y.; Hisel, Terri Z.; Hogan, Shannon D.; Maloney, Margaret M.; Chae, John

    2012-01-01

    Background Contralaterally controlled functional electrical stimulation (CCFES) is an experimental treatment intended to improve hand function after stroke. Objective To compare the effects of 6 weeks of CCFES vs. cyclic neuromuscular electrical stimulation (NMES) on upper extremity impairment and activity limitation in patients ≤ 6 months poststroke. Methods Twenty-one participants were randomized to CCFES or cyclic NMES. Treatment for both groups consisted of daily stimulation-assisted repetitive hand-opening exercise at home plus twice-weekly lab sessions of functional task practice. Assessments were made at pretreatment and posttreatment and at 1 month and 3 months posttreatment. They included maximum voluntary finger extension angle, finger movement tracking error, upper extremity Fugl-Meyer score, Box and Blocks test, and Arm Motor Abilities Test. Treatment effects were estimated using a 2-factor repeated measures analysis of variance with the value of the baseline measure as a covariate. Results Seventeen patients completed the treatment phase (9 CCFES, 8 cyclic NMES). At all post-treatment time points, CCFES produced larger improvements than cyclic NMES on every outcome measure. Maximum voluntary finger extension showed the largest treatment effect, with a mean group difference across the posttreatment time points of 28° more finger extension for CCFES. Conclusions The results favor CCFES over cyclic NMES though the small sample size limits the statistical power of the study. The effect size estimates from this study will be used to power a larger trial. PMID:21875892

  3. Identifying the ‘red flags’ for unhealthy weight control among adolescents: Findings from an item response theory analysis of a national survey

    Directory of Open Access Journals (Sweden)

    Utter Jennifer

    2012-08-01

    Full Text Available Abstract Background Weight control behaviors are common among young people and are associated with poor health outcomes. Yet clinicians rarely ask young people about their weight control; this may be due to uncertainty about which questions to ask, specifically around whether certain weight loss strategies are healthier or unhealthy or about what weight loss behaviors are more likely to lead to adverse outcomes. Thus, the aims of the current study are: to confirm, using item response theory analysis, that the underlying latent constructs of healthy and unhealthy weight control exist; to determine the ‘red flag’ weight loss behaviors that may discriminate unhealthy from healthy weight loss; to determine the relationships between healthy and unhealthy weight loss and mental health; and to examine how weight control may vary among demographic groups. Methods Data were collected as part of a national health and wellbeing survey of secondary school students in New Zealand (n = 9,107 in 2007. Item response theory analyses were conducted to determine the underlying constructs of weight control behaviors and the behaviors that discriminate unhealthy from healthy weight control. Results The current study confirms that there are two underlying constructs of weight loss behaviors which can be described as healthy and unhealthy weight control. Unhealthy weight control was positively correlated with depressive mood. Fasting and skipping meals for weight loss had the lowest item thresholds on the unhealthy weight control continuum, indicating that they act as ‘red flags’ and warrant further discussion in routine clinical assessments. Conclusions Routine assessments of weight control strategies by clinicians are warranted, particularly for screening for meal skipping and fasting for weight loss as these behaviors appear to ‘flag’ behaviors that are associated with poor mental wellbeing.

  4. Diet quality in obese/overweight individuals with/without metabolic syndrome compared to normal weight controls

    OpenAIRE

    Yosaee, Somaye; Esteghamati, Alireza; Nazari Nasab, Mahdiyeh; Khosravi, Ahmad; Alinavaz, Mina; Hosseini, Banafshe; Djafarian, Kurosh

    2016-01-01

    Background: Metabolic syndrome (MetS) is a serious public health concern worldwide; however, the pathogenesis of this disease has not been yet cleared. This study aimed to compare diet quality in obese/overweight participants with/without metabolic syndrome with normal weight controls. Methods: This was a comparative study on 147 Iranian adults under treatment at the Endocrinology Center of Tehran University of Medical Sciences. They were assigned into three groups (normal weight, obese weigh...

  5. Body image and weight control in young adults: international comparisons in university students from 22 countries.

    Science.gov (United States)

    Wardle, J; Haase, A M; Steptoe, A

    2006-04-01

    Young women in the United States and Western Europe are notoriously concerned about weight but less is known about attitudes to weight in other regions of the world. This study explores the associations between body mass index (BMI), weight perceptions, and attempts to lose weight in male and female university students from 22 countries. Data were collected from 18,512 university students, using standardised methods, as part of the International Health Behaviour Survey. Measures included weight, height, perception of overweight, and weight loss status. BMI was calculated from weight and height, but was categorised into gender and country-standardised deciles rather than the conventional weight categories in response to the inaccuracy of self-reports. Perceived overweight and weight loss status were plotted against country-standardised BMI deciles. The 22 countries were grouped into five geopolitical/economic areas for regional analyses: North-Western Europe and the USA, Central and Eastern Europe, the Mediterranean, Pacific Asia, South America. Perceived overweight compared across the five regions. Perceived overweight increased systematically across BMI deciles in all countries. More women than men felt overweight at any decile. Women had low levels of perceived overweight in the lowest decile but rates rapidly increased to 50% by the 5th decile. Men, even in the highest deciles, were less aware that they are overweight and few of them were trying to lose weight. Women had a faster rise of weight loss attempts over the BMI deciles but nevertheless the proportion trying to lose in the highest decile did not exceed 75%. Perceived overweight profiles across BMI deciles were similar across all regions, suggesting that perceptions of overweight derive from local comparisons. The patterning for trying to lose weight was more diverse, with men and women from Asian countries showing higher levels of trying to lose weight at all deciles. This study shows the international

  6. 基于ELM的机器人自适应跟踪控制%Adaptive tracking control of a rigid arm robot based on extreme learning machine

    Institute of Scientific and Technical Information of China (English)

    李军; 乃永强

    2015-01-01

    针对刚性臂机器人系统,提出基于极限学习机( ELM )的两种自适应神经控制算法。极限学习机随机选择单隐层前馈神经网络( SLFNs)的隐层节点及其参数,仅调整其网络的输出权值,以极快的学习速度可获得良好的推广性。在自适应控制算法中, ELM逼近系统的未知非线性函数,附加的鲁棒控制项补偿系统的逼近误差。 ELM神经控制器的参数自适应调整律及鲁棒控制项由Lyapunov稳定性理论分析得出,所设计的两种控制算法均不依赖于初始条件的约束且放松对参数有界的要求,同时保证闭环系统跟踪误差满足全局稳定而且渐近收敛于零。将所提出的ELM控制器应用于二连杆刚性臂机器人跟踪控制实例中,并与现有的径向基函数( RBF)神经网络自适应控制算法进行比较,仿真结果表明,在同等条件下,ELM控制器具有良好的跟踪控制性能,显示出其有效性和应用潜力。%Based on extreme learning machine ( ELM ) , two adaptive neural control algorithms for rigid arm robot system were presented. ELM for signle-hidden layer feedforward neural networks(SLFNs), which randomly chooses hidden node parameters and analytically determines the output weights of SLFNs, tends to provide good generalized performance at extremely fast learning speed. Within these adaptive control algorithms, ELM was employed to approximation the plant’ s unknown nonlinear function and ro-bust control term was used to compensate for approximation error. Parameter adaptive laws and robust control term of ELM controllers were derived based on Lyapunov stability analysis so that global stability and asymptotic convergence to zero of tracking errors can be guaranteed. Futhermore, two adaptive con-trollers do not depend on any parameter initialization conditions and relax the requirement of bounding pa-rameter values. The proposed adaptive ELM control algorithms were then applied to a tracking control in

  7. Effect of Smart Rotor Control Using a Deformable Trailing Edge Flap on Load Reduction under Normal and Extreme Turbulence

    Directory of Open Access Journals (Sweden)

    Jian Zhong Xu

    2012-09-01

    Full Text Available This paper presents a newly developed aero-servo-elastic platform for implementing smart rotor control and shows its effectiveness with aerodynamic loads on large-scale offshore wind turbines. The platform was built by improving the FAST/Aerodyn codes with the integration of an external deformable trailing edge flap controller in the Matlab/Simulink software. Smart rotor control was applied to an Upwind/NREL 5 MW reference wind turbine under various operating wind conditions in accordance with the IEC Normal Turbulence Model (NTM and Extreme Turbulence Model (ETM. Results showed that, irrespective of whether the NTM or ETM case was considered, aerodynamic load in terms of blade flapwise root moment and tip deflection were effectively reduced. Furthermore, the smart rotor control also positively affected generator power, pitch system and tower load. These results laying a foundation for a future migration of the “smart rotor control” concept into the design of large-scale offshore wind turbines.

  8. Adipose tissue CIDEA is associated, independently of weight variation, to change in insulin resistance during a longitudinal weight control dietary program in obese individuals.

    Science.gov (United States)

    Montastier, Emilie; Déjean, Sébastien; Le Gall, Caroline; Saris, Wim H M; Langin, Dominique; Viguerie, Nathalie

    2014-01-01

    Weight loss reduces risk factors associated with obesity. However, long-term metabolic improvement remains a challenge. We investigated quantitative gene expression of subcutaneous adipose tissue in obese individuals and its relationship with low calorie diet and long term weight maintenance induced changes in insulin resistance. Three hundred eleven overweight and obese individuals followed a dietary protocol consisting of an 8-week low calorie diet followed by a 6-month ad libitum weight-maintenance diet. Individuals were clustered according to insulin resistance trajectories assessed using homeostasis model assessment of insulin resistance (HOMA-IR) index. Adipose tissue mRNA levels of 267 genes selected for regulation according to obesity, metabolic status and response to dieting was assessed using high throughput RT-qPCR. A combination of discriminant analyses was used to identify genes with regulation according to insulin resistance trajectories. Partial correlation was used to control for change in body mass index. Three different HOMA-IR profile groups were determined. HOMA-IR improved during low calorie diet in the 3 groups. At the end of the 6-month follow-up, groups A and B had reduced HOMA-IR by 50%. In group C, HOMA-IR had returned to baseline values. Genes were differentially expressed in the adipose tissue of individuals according to groups but a single gene, CIDEA, was common to all phases of the dietary intervention. Changes in adipose tissue CIDEA mRNA levels paralleled variations in insulin sensitivity independently of change in body mass index. Overall, CIDEA was up-regulated in adipose tissue of individuals with successful long term insulin resistance relapse and not in adipose tissue of unsuccessful individuals. The concomitant change in adipose tissue CIDEA mRNA levels and insulin sensitivity suggests a beneficial role of adipose tissue CIDEA in long term glucose homeostasis, independently of weight variation. ClinicalTrials.gov NCT00390637.

  9. Adipose tissue CIDEA is associated, independently of weight variation, to change in insulin resistance during a longitudinal weight control dietary program in obese individuals.

    Directory of Open Access Journals (Sweden)

    Emilie Montastier

    Full Text Available AIM: Weight loss reduces risk factors associated with obesity. However, long-term metabolic improvement remains a challenge. We investigated quantitative gene expression of subcutaneous adipose tissue in obese individuals and its relationship with low calorie diet and long term weight maintenance induced changes in insulin resistance. RESEARCH DESIGN: Three hundred eleven overweight and obese individuals followed a dietary protocol consisting of an 8-week low calorie diet followed by a 6-month ad libitum weight-maintenance diet. Individuals were clustered according to insulin resistance trajectories assessed using homeostasis model assessment of insulin resistance (HOMA-IR index. Adipose tissue mRNA levels of 267 genes selected for regulation according to obesity, metabolic status and response to dieting was assessed using high throughput RT-qPCR. A combination of discriminant analyses was used to identify genes with regulation according to insulin resistance trajectories. Partial correlation was used to control for change in body mass index. RESULTS: Three different HOMA-IR profile groups were determined. HOMA-IR improved during low calorie diet in the 3 groups. At the end of the 6-month follow-up, groups A and B had reduced HOMA-IR by 50%. In group C, HOMA-IR had returned to baseline values. Genes were differentially expressed in the adipose tissue of individuals according to groups but a single gene, CIDEA, was common to all phases of the dietary intervention. Changes in adipose tissue CIDEA mRNA levels paralleled variations in insulin sensitivity independently of change in body mass index. Overall, CIDEA was up-regulated in adipose tissue of individuals with successful long term insulin resistance relapse and not in adipose tissue of unsuccessful individuals. CONCLUSION: The concomitant change in adipose tissue CIDEA mRNA levels and insulin sensitivity suggests a beneficial role of adipose tissue CIDEA in long term glucose homeostasis

  10. Chocolate cake. Guilt or celebration? Associations with healthy eating attitudes, perceived behavioural control, intentions and weight-loss.

    Science.gov (United States)

    Kuijer, Roeline G; Boyce, Jessica A

    2014-03-01

    Food and eating are often associated with ambivalent feelings: pleasure and enjoyment, but also worry and guilt. Guilt has the potential to motivate behaviour change, but may also lead to feelings of helplessness and loss of control. This study firstly examined whether a default association of either 'guilt' or 'celebration' with a prototypical forbidden food item (chocolate cake) was related to differences in attitudes, perceived behavioural control, and intentions in relation to healthy eating, and secondly whether the default association was related to weight change over an 18month period (and short term weight-loss in a subsample of participants with a weight-loss goal). This study did not find any evidence for adaptive or motivational properties of guilt. Participants associating chocolate cake with guilt did not report more positive attitudes or stronger intentions to eat healthy than did those associating chocolate cake with celebration. Instead, they reported lower levels of perceived behavioural control over eating and were less successful at maintaining their weight over an 18month period. Participants with a weight-loss goal who associated chocolate cake with guilt were less successful at losing weight over a 3month period compared to those associating chocolate cake with celebration.

  11. Weight Gain Prevention among Midlife Women: A Randomized Controlled Trial to Address Needs Related to the Physical and Social Environment

    Directory of Open Access Journals (Sweden)

    Courtney D. Perry

    2016-05-01

    Full Text Available Women tend to gain weight at midlife (40–60 years increasing risk of obesity-related chronic diseases. Within specific eating occasions, needs related to the physical and social environment may result in less healthy eating behavior, which can lead to weight gain over time. The purpose of this study was to determine if a dietitian-delivered nutrition counseling intervention tailored to eating occasion needs could improve diet and prevent weight gain among midlife women over two years. A randomized controlled trial was conducted with healthy midlife women (n = 354 in one U.S. metropolitan area. The intervention group (n = 185 received ten hours of individual nutrition counseling from dietitians over six months, while women in a control group (n = 169 received no counseling. Measured height, weight and waist circumference, and dietary intakes were collected at baseline and every six months over two years. Mixed linear models were used to test for intervention effect on change in outcome variables over time. Dietary intakes of fruit, reduced/low-fat dairy foods and refined grains were significantly improved over time in the intervention compared to control group. However, the intervention had no effect on weight over time (p = 0.48. Nutrition counseling tailored to address eating occasion needs improved self-reported diet but did not significantly affect weight change.

  12. Some optimal considerations in attitude control systems. [evaluation of value of relative weighting between time and fuel for relay control law

    Science.gov (United States)

    Boland, J. S., III

    1973-01-01

    The conventional six-engine reaction control jet relay attitude control law with deadband is shown to be a good linear approximation to a weighted time-fuel optimal control law. Techniques for evaluating the value of the relative weighting between time and fuel for a particular relay control law is studied along with techniques to interrelate other parameters for the two control laws. Vehicle attitude control laws employing control moment gyros are then investigated. Steering laws obtained from the expression for the reaction torque of the gyro configuration are compared to a total optimal attitude control law that is derived from optimal linear regulator theory. This total optimal attitude control law has computational disadvantages in the solving of the matrix Riccati equation. Several computational algorithms for solving the matrix Riccati equation are investigated with respect to accuracy, computational storage requirements, and computational speed.

  13. When feeling attractive matters too much to women: a process underpinning the relation between psychological need satisfaction and unhealthy weight control behaviors

    OpenAIRE

    Thøgersen-Ntoumani, Cecilie; Ntoumanis, Nikos; Cumming, Jennifer; Chatzisarantis, Nikos L. D.

    2011-01-01

    This study examined a process model linking psychological need satisfaction to unhealthy weight control behaviors. Female University students (N = 220; M age = 20.47; SD = 5.07) completed questionnaires measuring need satisfaction, appearance-contingent self-worth, weight-related appearance anxiety and unhealthy weight control behaviors. Structural equation modeling revealed that need satisfaction indirectly related to engagement in unhealthy weight control behaviors through appearance-contin...

  14. An adaptive metamaterial beam with hybrid shunting circuits for extremely broadband control of flexural wave (Conference Presentation)

    Science.gov (United States)

    Chen, Yangyang; Huang, Guoliang

    2017-04-01

    A great deal of research has been devoted to controlling the dynamic behaviors of phononic crystals and metamaterials by directly tuning the frequency regions and/or widths of their inherent band gaps. Here, we present a novel approach to achieve extremely broadband flexural wave/vibration attenuation based on tunable local resonators made of piezoelectric stacks shunted by hybrid negative capacitance and negative inductance circuits with proof masses attached on a host beam. First, wave dispersion relations of the adaptive metamaterial beam are calculated analytically by using the transfer matrix method. The unique modulus tuning properties induced by the hybrid shunting circuits are then characterized conceptually, from which the frequency dependent modulus tuning curves of the piezoelectric stack located within wave attenuation frequency regions are quantitatively identified. As an example, a flexural wave high-pass band filter with a wave attenuation region from 0 to 23.0 kHz is demonstrated analytically and numerically by using the hybrid shunting circuit, in which the two electric components are connected in series. By changing the connection pattern to be parallel, another super wide wave attenuation region from 13.5 to 73.0 kHz is demonstrated to function as a low-pass filter at a subwavelength scale. The proposed adaptive metamaterial possesses a super wide band gap created both naturally and artificially. Therefore, it can be used for the transient wave mitigation at extremely broadband frequencies such as blast or impact loadings. We envision that the proposed design and approach can open many possibilities in broadband vibration and wave control.

  15. Changes in eating attitudes, body esteem and weight control behaviours during adolescence in a South African cohort.

    Directory of Open Access Journals (Sweden)

    Tabither M Gitau

    Full Text Available Failure to consume an adequate diet or over consumption during adolescence can disrupt normal growth and development, resulting in undesirable weight change. This leads to an increase in unhealthy weight control practices related to eating and exercise among both adolescent girls and boys to meet the societal 'ideal' body shape. This study therefore aims to examine the longitudinal changes in eating attitudes, body-esteem and weight control behaviours among adolescents between 13 and 17 years; and, to describe perceptions around body shape at age 17 years. A total of 1435 urban South African black and mixed ancestry boys and girls, who had data at both age 13 and 17 years from the Birth to Twenty cohort were included. Data were collected through self-administered questionnaires on eating attitudes (EAT-26, body esteem and weight control behaviours for either weight loss or muscle gain attempts. Height and weight were measured at both time points and BMI was calculated. Black females had a higher BMI (p<0.001 and an increased risk of developing eating disorders as well as significant increase in the prevalence of weight loss practices between the ages 13 and 17 years. At age 17 years both Mixed ancestry adolescents had lower body-esteem compared to black adolescents. The prevalence of possible eating disorders was 11% and 13.1% in early and late adolescents respectively. Males and females shared similar opinions on normal silhouettes being the 'best', 'getting respect' and being the 'happiest', while the obese silhouette was associated with the 'worst' and the 'unhappiest', and the underweight silhouette with the "weakest". Black females had a higher BMI and an increased risk of developing eating disorders. Adolescent females engaged more in weight loss practices whereas, males in muscle gain practices indicating that Western norms of thinness as the ideal are becoming more common in South Africa.

  16. Disordered eating and the use of unhealthy weight control methods in college students: 1995, 2002, and 2008.

    Science.gov (United States)

    White, Sabina; Reynolds-Malear, Jocelyn B; Cordero, Elizabeth

    2011-01-01

    This study investigated whether eating disorders and the use of unhealthy weight control methods increased over time in male and female university undergraduate students. Data from three random sample surveys of college students were collected over a 13-year period to investigate trends in disordered eating and unhealthy weight control behaviors. Data were collected in 2008 from 641 male and female randomly sampled undergraduate students were compared to 274 randomly sampled undergraduates surveyed in 2002 and 493 surveyed in 1995. Behaviors falling within the diagnostic category of eating disorders not otherwise specified (EDNOS) in both males and females significantly increased over time in accordance with the use of unhealthy weight control methods. Eating disorders should be routinely addressed by college health professionals through both treatment and prevention efforts, especially considering the frequent concurrent psychiatric and physiological comorbidities.

  17. Relation of selective voluntary motor control of the lower extremity and extensor strength of the knee joint in children with spastic diplegia.

    Science.gov (United States)

    Kusumoto, Yasuaki; Takaki, Kenji; Matsuda, Tadamitsu; Nitta, Osamu

    2016-06-01

    [Purpose] The aim of this study was to investigate differences in selective voluntary motor control of the lower extremities by objective assessment and determine the relationship between selective voluntary motor control and knee extensor strength in children with spastic diplegia. [Subjects and Methods] Forty individuals who had spastic cerebral palsy, with Gross Motor Function Classification System levels ranging from I to III, were assessed using the Selective Control Assessment of the Lower Extremity and by testing the maximum knee extensor strength. The unaffected side was defined as the lower limb with the higher score, and the affected side was defined as the lower limb with the lower score. [Results] The Selective Control Assessment of the Lower Extremity score on the affected side had a lower average than that on the unaffected side. The scores showed a significant inverse correlation with the maximum knee extensor strength. [Conclusion] There was bilateral difference in the selective voluntary motor control of the lower extremities in children with spastic diplegia, and the selective voluntary motor control of the lower extremity was related to maximum knee extensor strength.

  18. Eating attitudes, weight control behaviors and risk factors for eating disorders among Chinese female dance students

    Directory of Open Access Journals (Sweden)

    Zhuoli Tao

    Full Text Available Background and Objectives: Along with the economic development, eating disorders begin to appear in China. In this context, we study potential risks for eating disorders. Methods: 1,199 Chinese students, aged 12-25 years, were randomly selected in spring 2006 from a survey with a series of scales (EAT-26, EDI that were used as a screening examination for eating attitudes, weight control behaviors and risk factors. Among them were 31 female Chinese dance students. The dancer students were compared with the female high risk group of eating disorders (EAT ≥ 20 and the female low risk group (EAT 0-9 according to their scores on EAT-26 and EDI. Results: There were just 3 dancers (10% with scores on the EAT-26 who were over the cut-off point of 20 for high risk of an eating disorder. The dance group also showed significantly higher scores than the low risk group (EAT 0-9 not only on the subscales Dieting, and EAT-26 total scores on the EAT-26, but also on the subscales Perfectionism and Maturity Fears on the EDI. Conclusions: Among the group of female Chinese dance students, most participants did not show a high risk for eating disorders and their high scores on some subscales on the EAT-26 and EDI could be caused by their occupation.

  19. Weighted Activity and Costing of Surveillance and Control in Animal Epidemiology

    Directory of Open Access Journals (Sweden)

    Duboz Raphaël

    2013-01-01

    Full Text Available Activity based modeling and simulation is a very promising field. It has recently demonstrated its potential from modeling software development methods [9] to the design of low energy sensors. In this position paper, I would like to initiate a reflexion on the use of the weighted activity in the context of financial costing using the formulation recently proposed by X. Hu and B.P. Zeigler [5]. I propose here to formalize a recent approach of costing, the Time-Driven Activity Based Costing [3], using the theoretical modeling framework initiated by B.P. Zeigler [6]. I argue that this specification can potentially improve the traditional model of Time-Driven Activity Based Costing. I illustrate the approach in the context of surveillance and control in animal epidemiology. The demonstration of its effectiveness is not done in this position paper. Nevertheless, as the existing costing systems are designed to support decision making in business management, the scenario based approach proposed in this paper should be very useful to support decisions in complex management situations.

  20. Extreme soil erosion rates in citrus slope plantations and control strategies. A literature review

    Science.gov (United States)

    Cerdà, Artemi; Ángel González Peñaloza, Félix; Pereira, Paulo; Reyes Ruiz Gallardo, José; García Orenes, Fuensanta; Burguet, María

    2013-04-01

    Soil Erosion is a natural process that shapes the Earth. Due to the impact of agriculture, soil erosion rates increase, landforms show gullies and rills, and soils are depleted. In the Mediterranean, wheat, olive and vineyards were the main agriculture products, but new plantations are being found in sloping terrain due to the drip-irrigation. This new strategy results in the removal of the traditional terraces in order to make suitable for mechanization the agriculture plantation. Citrus is a clear example of the impact of the new chemical agriculture with a high investment in herbicides, pesticides, mechanisation, land levelling and drip computer controlled irrigation systems. The new plantation of citrus orchards is found in the Mediterranean, but also in California, Florida, China and Brazil. Chile, Argentina, and South Africa are other producers that are moving to an industrial production of citrus. This paper shows how the citrus plantations are found as one of the most aggressive plantation due to the increase in soil erosion, and how we can apply successful control strategies. The research into the high erosion rates of citrus orchard built on the slopes are mainly found in China (Wu et al., 1997; Xu et al., 2010; Wang et al., 2011; Wu et al., 2011; Liu et al., 2011; Lü et al., 2011; Xu et al., 2012) and in the Mediterranean (Cerdà and Jurgensen, 2008; 2009; Cerdà et al., 2009a; 2009b; Cerdà et al., 2011; 2012) Most of the research done devoted to the measurements of the soil losses but also some research is done related to the soil properties (Lu et al., 1997; Lü et al., 2012; Xu et al., 2012) and the impact of cover crops to reduce the soil losses (Lavigne et al., 2012; Le Bellec et al., 2012) and the use of residues such as dried citrus peel in order to reduce the soil losses. There are 116 million tonnes of citrus produced yearly, and this affects a large surface of the best land. The citrus orchards are moving from flood irrigated to drip

  1. Extreme Heat

    Science.gov (United States)

    ... Landslides & Debris Flow Nuclear Blast Nuclear Power Plants Power Outages Pandemic Radiological Dispersion Device Severe Weather Snowstorms & Extreme ... Landslides & Debris Flow Nuclear Blast Nuclear Power Plants Power Outages Pandemic Radiological Dispersion Device Severe Weather Snowstorms & Extreme ...

  2. Epidural injection with or without steroid in managing chronic low back and lower extremity pain: ameta-analysis of ten randomized controlled trials

    OpenAIRE

    Zhai, Jinshuai; Zhang, Long; Li, Mengya; Tian, Yiren; Zheng, Wang; Chen, Jia; Huang, Teng; Li, Xicheng; Tian, Zhi

    2015-01-01

    Background: Chronic low back and lower extremity pain is mainly caused by lumbar disc herniation (LDH) and radiculitis. Various surgery and nonsurgical modalities, including epidural injections, have been used to treat LDH or radiculitis. Therefore, we conducted this meta-analysis to assess the effects of the two interventions in managing various chronic low and lower extremity pain. Methods: A systematic literature search was conducted to identify randomized controlled trials (RCTs) which co...

  3. [Assessing various aspects of the motivation to eat that can affect food intake and body weight control].

    Science.gov (United States)

    Bellisle, F

    2009-04-01

    Over the last 30 years, several questionnaires have been developed and validated in order to assess many aspects of the motivation to eat that might be susceptible to impair adequate food intake and body weight control. A few of such questionnaires are described here, in particular, the "Three Factor Eating Questionnaire" also called the "Eating Inventory", and the "Dutch Eating Behavior Questionnaire". Critical aspects of the motivation to eat assessed by these tools are presented, such as dietary restraint, disinhibition, hunger, vulnerability to eat in response to external cues or emotional states, etc. These questionnaires were developed for use in the general population with the aim to identify critical aspects of the motivation to eat that might predispose to weight gain. They have been widely used in many countries and have allowed an improved understanding of the individual characteristics that predispose to body weight gain or resistance to weight loss. Originally, poor body weight control was attributed to a high level of dietary "restraint", or in other words, the tendency to deliberately restrict one's food intake for body weight control purposes. Such dietary restraint was suspected to lead to a number of physical and psychological difficulties, among which poor self-esteem and a paradoxical tendency to gain weight, resulting from the incapacity to maintain strict restraint over time. More recent studies have established that a motivational trait called "Disinhibition" is a strong predictor of body weight gain over time and of poor outcome of dieting. "Disinhibition" corresponds to a tendency to lose control over one's eating behavior and ingest excessively large quantities of food substances, in response to a variety of cues and circumstances. In addition to its untoward effect on weight, disinhibition also predicts various risk factors and pathologies, such as hypertension and diabetes. Other potentially critical dimensions for adequate body weight

  4. Behavioral change during weight loss program and one-year follow-up: Saku Control Obesity Program (SCOP) in Japan.

    Science.gov (United States)

    Nakade, Makiko; Aiba, Naomi; Suda, Naomi; Morita, Akemi; Miyachi, Motohiko; Sasaki, Satoshi; Watanabe, Shaw; SCOP Group

    2012-01-01

    This study evaluated effects of a behavioral approach which placed emphasis on tailored behavior counseling, diet, weight loss and weight maintenance. A one-year randomized controlled trial was conducted among 235 overweight/obese adults in Japan. The intervention group (n=119) received individual-based counseling using a behavioral approach and the changes made in the diet and physical activity were dependent on each participant as much as possible. One year later, the intervention group lost significantly more weight than the control group (-5.0 kg vs. 0.1 kg for men and -3.9 kg vs. -0.2 kg for women). Compared to the control group, the male intervention group reduced overall energy, cereals and dairy products consumption significantly, while increasing green and yellow vegetable intake, and the female intervention group significantly reduced intake of dairy products. Regarding behaviors, both male and female intervention groups increased the number of walking steps and women improved their irregular eating habits compared to those in the control groups. Behavior changes were related to weight loss; participants who maintained the action/maintenance stage or moved to later stages lost significantly more weight than participants who remained in the pre-contemplation/contemplation/preparation stages or regressed to earlier stages. After one-year follow-up, the intervention group maintained significantly lower weights, lower energy intakes and improvements in irregular eating habits. Our behavioral approach led to diet and behavior modification, weight loss and maintenance. Because modified variables differed between men and women, gender-specific approaches may be necessary.

  5. Mandelbrot's Extremism

    NARCIS (Netherlands)

    Beirlant, J.; Schoutens, W.; Segers, J.J.J.

    2004-01-01

    In the sixties Mandelbrot already showed that extreme price swings are more likely than some of us think or incorporate in our models.A modern toolbox for analyzing such rare events can be found in the field of extreme value theory.At the core of extreme value theory lies the modelling of maxima

  6. Effect of an Exercise and Weight Control Curriculum: Views of Obesity among Exercise Science Students

    Science.gov (United States)

    Richardson, Laura A.; Fister, Carrie L.; Ramlo, Susan E.

    2015-01-01

    Awareness of effective weight management strategies is necessary to prepare exercise science students for future work with obesity. Exercise science faculty members developed a course related to exercise as a therapeutic tool and options available for weight loss. The purpose of the present study was to investigate student views of weight…

  7. Age-related differences in the control of weight-shifting within the surface of support

    NARCIS (Netherlands)

    de Vries, E.; Caljouw, S.R.; Coppens, M.J.M.; Postema, K.; Verkerke, Gijsbertus Jacob; Lamoth, C.J.C.

    2014-01-01

    BACKGROUND AND AIM: An important reason for falling in elderly is incorrect weight-shifting¹. In many daily life activities quick and accurate weight-shifting is needed to maintain balance, especially in situations when balance is suddenly disturbed and anticipation on the upcoming movement is diffi

  8. Effect of an Exercise and Weight Control Curriculum: Views of Obesity among Exercise Science Students

    Science.gov (United States)

    Richardson, Laura A.; Fister, Carrie L.; Ramlo, Susan E.

    2015-01-01

    Awareness of effective weight management strategies is necessary to prepare exercise science students for future work with obesity. Exercise science faculty members developed a course related to exercise as a therapeutic tool and options available for weight loss. The purpose of the present study was to investigate student views of weight…

  9. A randomized controlled trial of a commercially available weight loss program

    Science.gov (United States)

    The U.S. Preventive Services Task Force (USPSTF) recommends that clinicians refer obese adults for intensive, multi-component behavioral counseling, yet most obese Americans choose a self-help approach to lose weight. The current study examined weight loss between a community-based, intensive behavi...

  10. A randomized, controlled trial of 3.0 mg of Liraglutide in weight management

    DEFF Research Database (Denmark)

    Pi-Sunyer, Xavier; Astrup, Arne; Fujioka, Ken

    2015-01-01

    Background Obesity is a chronic disease with serious health consequences, but weight loss is difficult to maintain through lifestyle intervention alone. Liraglutide, a glucagon-like peptide-1 analogue, has been shown to have potential benefit for weight management at a once-daily dose of 3.0 mg, ...

  11. Ingestion of High Molecular Weight Carbohydrate Enhances Subsequent Repeated Maximal Power: A Randomized Controlled Trial

    Science.gov (United States)

    Oliver, Jonathan M.; Almada, Anthony L.; Van Eck, Leighsa E.; Shah, Meena; Mitchell, Joel B.; Jones, Margaret T.; Jagim, Andrew R.; Rowlands, David S.

    2016-01-01

    Athletes in sports demanding repeat maximal work outputs frequently train concurrently utilizing sequential bouts of intense endurance and resistance training sessions. On a daily basis, maximal work within subsequent bouts may be limited by muscle glycogen availability. Recently, the ingestion of a unique high molecular weight (HMW) carbohydrate was found to increase glycogen re-synthesis rate and enhance work output during subsequent endurance exercise, relative to low molecular weight (LMW) carbohydrate ingestion. The effect of the HMW carbohydrate, however, on the performance of intense resistance exercise following prolonged-intense endurance training is unknown. Sixteen resistance trained men (23±3 years; 176.7±9.8 cm; 88.2±8.6 kg) participated in a double-blind, placebo-controlled, randomized 3-way crossover design comprising a muscle-glycogen depleting cycling exercise followed by ingestion of placebo (PLA), or 1.2 g•kg•bw-1 of LMW or HMW carbohydrate solution (10%) with blood sampling for 2-h post-ingestion. Thereafter, participants performed 5 sets of 10 maximal explosive repetitions of back squat (75% of 1RM). Compared to PLA, ingestion of HMW (4.9%, 90%CI 3.8%, 5.9%) and LMW (1.9%, 90%CI 0.8%, 3.0%) carbohydrate solutions substantially increased power output during resistance exercise, with the 3.1% (90% CI 4.3, 2.0%) almost certain additional gain in power after HMW-LMW ingestion attributed to higher movement velocity after force kinematic analysis (HMW-LMW 2.5%, 90%CI 1.4, 3.7%). Both carbohydrate solutions increased post-exercise plasma glucose, glucoregulatory and gut hormones compared to PLA, but differences between carbohydrates were unclear; thus, the underlying mechanism remains to be elucidated. Ingestion of a HMW carbohydrate following prolonged intense endurance exercise provides superior benefits to movement velocity and power output during subsequent repeated maximal explosive resistance exercise. This study was registered with

  12. No evidence of insulin resistance in normal weight vegetarians. A case control study.

    Science.gov (United States)

    Valachovicová, Martina; Krajcovicová-Kudlácková, Marica; Blazícek, Pavel; Babinská, Katarína

    2006-02-01

    Diets rich in carbohydrates with a low glycemic index and with high fiber content are associated with flat post-prandial rises of blood glucose, minimal post-prandial insulin secretion and maintenance of insulin sensitivity. Protective food commodities in the prevention of cardiovascular disease, insulin resistance syndrome or diabetes are crucial components of the vegetarian diet. Insulin resistance values were assessed in relation to different nutrition. Metabolic abnormality is a predictor of age-related diseases and can be more pronounced in obese subjects. Insulin resistance values in normal weight subjects of two different nutritional habits were correlated with age. Fasting concentrations of glucose and insulin as well as calculated values of insulin resistance IR (HOMA) were assessed in two nutritional groups of apparently healthy adult subjects (age range 19 - 64 years) with normal weight (body mass index 18.6 - 25.0 kg/m(2)): a vegetarian group (95 long-term lacto-ovo-vegetarians; duration of vegetarianism 10.2 +/- 0.5 years) and a non-vegetarian control group (107 subjects of general population on traditional western diet). Intake of energy and main nutrients (fats, saccharides, proteins) was similar in both groups. Glucose and insulin concentrations and IR (HOMA) values were significantly lower in vegetarians (glucose 4.47 +/- 0.05 vs. 4.71 +/- 0.07 mmol/l; insulin 4.96 +/- 0.23 vs. 7.32 +/- 0.41 mU/l; IR (HOMA) 0.99 +/- 0.05 vs. 1.59 +/- 0.10). IR (HOMA) dependence on age was only significant in subjects on a western diet. A significant increase of IR was found already in the age range 31-40 years, compared to vegetarians and it continued in later age decades. Age independent and low insulin resistance values in vegetarians are a consequence of an effective diet prevention by long-term frequent consumption of protective food. Vegetarians had a significantly higher consumption of whole grain products, pulses, products from oat and barley. The results of

  13. Acarbose improves glycemic control and reduces body weight: Subanalysis data of South Asia region

    Directory of Open Access Journals (Sweden)

    S Kalra

    2013-01-01

    Full Text Available Alpha-glucosidase inhibitors (AGIs are widely used especially in Asian countries as a treatment option for type 2 diabetes patients with high postprandial glycaemia. However, data from South Asia region is very limited. In order to examine the effect of AGI in real-life setting, 10 PMS/NIS from all over the world from the launch of acarbose to date were pooled in one database and exploratory analysis was performed for glycemic parameters and weight. In total 62,905 patients were pooled from 21 countries and regions. Mean follow up (± SD was 12.2 ± 4.8 weeks (range 0.1-108.9. From South Asia region (India and Pakistan, 8,738 Asian patients were enrolled. Mean PPG decreased from 240.0 and 261.1 mg/dl at baseline by 70.26 ± 65.10 and 82.96 ± 56.59 mg/dl at the last visit in total and South Asian populations, respectively (n = 53,883; n = 7,991, P < 0.0001 for both. Mean FPG decreased from 171.6 and 176.5 mg/dl at baseline by 38.48 ± 47.83 and 49.59 ± 41.41 mg/dl at the last visit in total and South Asian populations, respectively (n = 56,672; n = 7,837, P < 0.0001 for both. Mean HbA1c decreased from 8.4 and 8.4% at baseline by 1.11 ± 1.31% and 0.91 ± 0.93% at the last visit in total and South Asian populations, respectively (n = 38,843; n = 2,343, P < 0.0001 for both. Mean relative reduction of body weight (BW was 1.40 ± 3.28% and 1.10 ± 3.39% at the last visit for mean baseline BW 73.6 and 74.2 kg in total and South Asian populations, respectively (n = 54,760; n = 7,718, P < 0.0001 for both. Consistent with RCT meta-analyses, post-hoc analysis of real-life data showed acarbose treatment improved glycaemic control and reduced the BW. Acarbose treatment in real life setting showed significant reductions in all glycemic parameters and BW in Asian patients from South Asia region.

  14. Determinantes fisiológicos do controle do peso e apetite Physiological determinants of weight and appetite control

    Directory of Open Access Journals (Sweden)

    Zuleika S. C. Halpern

    2004-01-01

    Full Text Available A obesidade é um dos principais problemas de saúde pública d