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Sample records for extra nuchal-type fibroma

  1. Extra nuchal-type fibroma associated with elastosis, traumatic neuroma, a rare APC gene missense mutation, and a very rare MUTYH gene polymorphism: a case report and review of the literature*.

    Science.gov (United States)

    Linos, Konstantinos; Sedivcová, Monika; Cerna, Katerina; Sima, Radek; Kazakov, Dmitry V; Nazeer, Tipu; Glazyrin, Alexey; Valerian, Brian T; Carlson, J Andrew

    2011-11-01

    We report a case of an extra nuchal-type fibroma in a 51-year-old male suspected to have attenuated familial adenomatous polyposis (Gardner's syndrome), who presented with a longstanding buttock mass excised due to enlargement and pain. Histopathologically, lobules of haphazard, hypocellular, hyalinized collagen bundles replaced the dermis and subcutis and entrapped nerve bundles, mimicking Morton neuroma. Ramifying nerve twigs found around larger nerve fascicles showed the co-existence of traumatic neuroma. Elastic tissue stain revealed elastosis characterized by large, arborizing fibers lying between and within the hyalinized collagen bundles. Modified Masson's trichrome stain showed light blue staining of collagen bundles producing the hyalinized nodules with irregular, light red staining of collagen bundles at their periphery and within tumor collagen. Compression and/or degeneration of collagen and secondary elastosis with later entrapment by tumor collagen could explain this microscopic phenotype. By immunohistochemistry, tumor spindle cells expressed nuclear β-catenin and cyclin D1, mostly within regions of fibrosis implicating activation of the adenomatous polyposis coli (APC)-Wnt pathway. Genetic analysis showed a missense mutation in APC gene (c.7504G>A, p.G2502S in exon 15) and a functional homozygous polymorphism in the MUTYH gene (c.36+325G>C, (IVS1+5G/C)). Nuchal-type fibroma has been associated with Gardner's syndrome and trauma. In this patient, genetic predisposition coupled with repetitive, localized trauma and collagen degeneration may have provided the stimulus for the development of extra nuchal-type fibroma.

  2. Fibroma nuchae i nakkeregionen

    DEFF Research Database (Denmark)

    Møller, Michael; Sørensen, Flemming Brandt

    2014-01-01

    Nuchal-type fibroma is a benign tumour usually presenting in the posterior region of the neck. It was first described in 1988, and the largest publication includes 52 cases of nuchal-type fibroma. It can easily be confused with lipoma, but upon surgical exploration it reveals as poorly defined...... and difficult to dissecate. Histologically nuchal-type fibroma is a paucicellular tumour with thick, randomly arranged collagen fibres with centrally lobulated architecture. We present three cases of nuchal-type fibroma....

  3. Nonossifying Fibroma

    Science.gov (United States)

    ... Copyright 2011 American Academy of Orthopaedic Surgeons Nonossifying Fibroma Nonossifying fibromas (NOFs) are the most common benign bone tumor ... 43% of NOFs occur in the tibia. Nonossifying fibromas are made of fibrous tissue and are typically ...

  4. Desmoplastic Fibroma of Bone: Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Yun; Ha, Dong Ho; Kim, Dong Won [Dept. of Radiology, Dong A University College of Medicine, Seoul (Korea, Republic of); Kim, Su Jin [Dept. of Pathology, Dong A University College of Medicine, Seoul (Korea, Republic of)

    2011-05-15

    Desmoplastic fibroma of bone is a rare benign primary bone tumor that histologically resembles the extra-abdominal desmoid tumor of soft tissues. It is a nonmetastasizing, but locally aggressive tumor that is similar to a desmoid tumor of the soft tissues, and so it is considered 'semimalignant'. According to a previous report on a series of bone tumors, the incidence rate of desmoplastic fibroma was 0.1-0.3%. Its rarity results in radiologists having a tendency of overlooking the possibility of desmoplastic fibroma of bone during the imaging readings. We report on the imaging findings of desmoplastic fibroma of bone with a review of the relevant literature.

  5. Plantar Fibroma

    Science.gov (United States)

    ... it can also arise when walking or standing barefoot. Diagnosis To diagnose a plantar fibroma, the foot ... Where do you hurt? Interactive Foot Diagram Going Barefoot? Beware! Tips for a safer barefoot summer. Millions ...

  6. Ameloblastic fibroma

    Directory of Open Access Journals (Sweden)

    C H Lalitha

    2016-01-01

    Full Text Available Ameloblastic fibroma, is a mixed odontogenic tumor, which commonly affects young children under the age of 20 years, with the mandibular premolar-molar region being the most common site of manifestation. This is a case report of a 25-year-old female with a swelling in the right posterior mandibular region since 4 months, which was subsequently diagnosed as ameloblastic fibroma.

  7. Ameloblastic Fibroma

    Directory of Open Access Journals (Sweden)

    Marieh Honarmand

    2013-01-01

    Full Text Available Ameloblastic fibroma is a rare mixed odontogenic tumor [1, 2].The average age of affliction is 15 years old [3]. Tumor growth is slow and painless and leads to an expansion of jaws and migration and displacement of teeth and it is often asymptomatic [2, 3]. Several cases of malignant transformation to Ameloblastic fibrosarcoma (AFS have been reported [4].

  8. Ovary fibroma

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    María del Pilar Estrada Pérez

    2015-12-01

    Full Text Available The ovary fibroma is a solid tumor of very low frequency, scarcely from 1 to 4 % of all benign neoplasms in that gonad. The condition can be asymptomatic or with scarce manifestations, at the time it has been confused with malignant lesions. This is the case of a postmenopausal woman with an increase of volume of her lower right abdomen; at palpation, an immotile and hard tumoral mass of about 10 cm in diameter was found. To the vaginal touch, the volume increase, predominantly solid, was located in the right annex. The ultrasound reported a bladder slightly out of its place. The abdominal computed tomography showed that the colon and the bladder were compressed and moved up to the left by the lesion. The patient underwent surgery and the biopsy informed an ovary fibroma, as well as other disorders of that side of the uterus and the ovary.

  9. Ameloblastic fibroma.

    Science.gov (United States)

    Rao, Srinivas Ponnam; Srivastava, Gautam; Smitha, B

    2012-09-01

    Ameloblastic fibroma is a rare odontogenic tumor comprising neoplastic epithelial and mesenchymal tissues. This lesion was previously considered to be a benign lesion with very limited recurrence rate and malignant transformation. However, recent reports have suggested that this lesion has the potential for recurrence and malignant transformation. In this brief report, we report a case of AF in the context of its high cellularity on histopathological examination.

  10. Giant Cell Fibroma

    OpenAIRE

    Tahere Nosratzehi; Lale Maleki

    2013-01-01

    Giant cell fibroma is a fibrous tumor which represents about 2 to 5% of all oral fibrotic proliferations. Compared to traumatic fibroma, giant (traumatic fibroma or irritation fibroma) cell fibroma occurs at a younger age. In about 60% of the cases the lesion is diagnosed within the first three decades of life and is slightly more in women. 50% of the cases is observed in the gum and will appear as a nodule with a papillary surface [1]. The giant cell fibroma is treated by conservative excisi...

  11. Peripheral Ossifying Fibroma

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    Sudhakar S

    2009-11-01

    Full Text Available Peripheral ossifying fibroma is a relatively uncommon gingival growth that is considered to be reactive in nature and postulated to appear secondary to irritation or trauma. They usually occur in young adults with a female predominance and are solitary in nature. We report a case of peripheral ossifying fibroma in a 55-year old female.

  12. Peripheral ameloblastic fibroma.

    Science.gov (United States)

    Darling, M R; Daley, T D

    2006-03-01

    Peripheral ameloblastic fibroma is an exceedingly rare lesion. Only three reports could be found, two of which appeared in the Japanese literature. Here, we report a case of peripheral ameloblastic fibroma occurring in a 5-year-old girl. The diagnosis was made after careful microscopic examination, to exclude other lesions. The lesion was excised and has not recurred 1 year after removal.

  13. Cemento-ossifying fibroma.

    Science.gov (United States)

    Ram, Rangila; Singhal, Anita; Singhal, Parul

    2012-01-01

    The cemento-ossifying fibroma is classified as a fibro-osseous lesion of the jaws. It commonly presents as a progressively growing lesion that can attain an enormous size with resultant deformity if left untreated. A case of cemento-ossifying fibroma involving the left mandible is described in a 35 year old female patient. The clinical, radiographic and histological features as well as surgical findings are presented. The cemento-ossifying fibroma is a central neoplasm of bone as well as the periodontium which has caused considerable controversy because of the confusion regarding terminology and the criteria for its diagnosis.

  14. Desmoplastic fibroma of mandible

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    Yadavalli Guruprasad

    2015-01-01

    Full Text Available Desmoplastic fibroma is a rare benign intraosseous tumor with locally aggressive behavior. The mandible is the most frequent site of involvement. It causes bone destruction with a tendency to invade the soft-tissues if untreated. It has a high propensity for local recurrence if treated inadequately. We report a case of desmoplastic fibroma of the mandible treated with a wide margin of excision.

  15. MRI of chondromyxoid fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Hyun-Soo; Jee, Won-Hee (Dept. of Radiology, Seoul St Mary' s Hospital, School of Medicine, The Catholic Univ. of Korea, Seoul (Korea, Republic of)), email: whjee@catholic.ac.kr; Ryu, Kyung-Nam (Dept. of Radiology, Kyung Hee Univ. School of Medicine, Seoul (Korea, Republic of)) (and others)

    2011-10-15

    Background Chondromyxoid fibroma is a rare benign primary bone tumor of cartilage. Despite a characteristic radiographic appearance, chondromyxoid fibroma with atypical radiographic findings may mimic more common tumors. Purpose To describe the MR findings of chondromyxoid fibroma. Material and Methods MR images of 19 histopathologically confirmed chondromyxoid fibromas were retrospectively analyzed for signal intensity, periosteal reaction, adjacent abnormal bone marrow and soft tissue signal, and patterns of contrast enhancement. Results All cases of chondromyxoid fibroma showed hypointense to intermediate signal intensity and internal hyperintense foci were observed in seven (37%) cases on T1-weighted images. On T2-weighted images, all lesions were hyperintense: peripheral intermediate signal band with central hyperintense signal in 11 (58%) of 19 lesions, whereas diffusely hyperintense with heterogeneous pattern in eight (42%). Periosteal reaction was observed in 11 (58%) of 19 cases. Adjacent abnormal bone marrow or soft tissue signal was observed in 12 (63%) or 14 (74%) of 19 cases, respectively. On contrast-enhanced T1-weighted images, peripheral nodular enhancement was observed in 69% (11/16) and diffuse contrast enhancement was observed in 31% (5/16) with homogeneous (n = 3) or heterogeneous (n = 2) patterns. Among the cases with peripheral nodular enhancement, the peripheral nodular enhancing portion generally corresponded to the peripheral intermediate signal band on T2-weighted images, although the peripheral enhancement was not as wide as a band of intermediate signal intensity. On the other hand, the central non-enhancing portion generally corresponded to the central hyperintense signal intensity on T2-weighted images. Conclusion The helpful features of chondromyxoid fibroma are the peripheral intermediate signal band and central hyperintense signal on T2-weighted images, generally corresponding to the peripheral nodular enhancement and central non

  16. Chondroblastoma and chondromyxoid fibroma.

    Science.gov (United States)

    De Mattos, Camila B R; Angsanuntsukh, Chanika; Arkader, Alexandre; Dormans, John P

    2013-04-01

    Chondroblastoma and chondromyxoid fibroma are benign but locally aggressive bone tumors. Chondroblastoma, a destructive lesion with a thin radiodense border, is usually seen in the epiphysis of long bones. Chondromyxoid fibroma presents as a bigger, lucent, loculated lesion with a sharp sclerotic margin in the metaphysis of long bones. Although uncommon, these tumors can be challenging to manage. They share similarities in pathology that could be related to their histogenic similarity. Very rarely, chondroblastoma may lead to lung metastases; however, the mechanism is not well understood.

  17. Odontogenic fibroma, including amyloid and ossifying variants.

    Science.gov (United States)

    Eversole, Lewis R

    2011-12-01

    Sixty-five cases of odontogenic fibroma (OdonF) are herein presented having been segregated into peripheral, extra bony tumors (n = 40) and tumors arising in bone or centrally (n = 25). All cases were characterized microscopically by a fibrous proliferation that varied within and between cases in cellularity and collagen fibril diameter, with intermixed odontogenic epithelial islands and cords. All central lesions presented as well demarcated radiolucencies and resorption of contiguous tooth roots was a common finding. These intraosseous lesions were of the WHO type; the so-called nonWHO type was excluded as all lesions with this diagnosis were devoid of an epithelial component and could be reclassified as other soft tissue fibrogenic tumors. Neither the central tumors nor the peripheral lesions recurred following enucleation/curettage, with a mean follow-up of 4 and 3.4 years respectively. Three distinct microscopic variations were encountered in this series: (1) two cases of OdonF with giant cell reaction, (2) two instances of OdonF with ossifying fibroma; and (3) four instances of OdonF with odontogenic ameloblast-associated protein (ODAM), an amyloid-like protein found deposited adjacent to epithelial cords plus CD1a+/S-100+ Langerhans dendritic cells entwined around the epithelial element. A single instance of the odontogenic fibroma-like hamartoma/enamel hypoplasia syndrome has been included in this series.

  18. Calcified retroperitoneal fibroma.

    Science.gov (United States)

    Illuminati, G; Bertagni, A; Montesano, G; Soda, G; Baiocchini, A; Melis, M; Vietri, F

    1997-01-01

    A case of 31-year-old male with a retroperitoneal tumor is described. Abdominal ultrasound revealed a left para-aortic calcific mass, adjacent to the left lobe of the liver and to the upper pole of the left kidney. A CT-scan of the abdomen showed the mass to originate from the left adrenal gland. At operation, a large, retroperitoneal mass, adherent to the left kidney and the spleen, but not infiltrating, was excised. Histologically the tumor was diagnosed as a calcified osteo-producing fibroma. Benign retroperitoneal tumors represent about 25% of all retroperitoneal neoplasm. This reported case represents a retroperitoneal tumor of slow growth and benign clinical course whose characteristic consists of the heavy calcifications which are normally absent in a fibroma type mass.

  19. Fibroma of tendon sheath.

    Science.gov (United States)

    Smith, P S; Pieterse, A S; McClure, J

    1982-01-01

    A series of nine cases of fibroma of tendon sheath is described including details of the ultrastructural features of two cases. The series was composed of lesions from six males and three females with a mean age of 38 yr. The most common site of involvement was the hand (including fingers) and the mean greater diameter was 19 mm. Typically the tumours were lobulated and microscopically there was a collagenous stroma with spindle and stellate cells in a moderate degree of cellularity. One recurrence was noted in the series. The lesion was distinguished from circumscribed fibromatosis, nodular fasciitis, neurofibroma, leiomyoma, scar tissue, giant cell tumour of tendon sheath (localised nodular tenosynovitis) and fibrous histiocytoma. Ultrastructural studies revealed that the large majority of cells present in the two cases studied were myofibroblasts and fibroma of tendon sheath is therefore the third instance of a benign tumour containing these cells (the other two being dermatofibroma and giant cell fibroma of the oral mucosa). Images PMID:7107956

  20. Intracortical chondromyxoid fibroma of humerus

    Energy Technology Data Exchange (ETDEWEB)

    Fujiwara, Sayaka; Nakamura, Ichiro; Goto, Takahiro; Yokokura, Satoshi; Nakamura, Kozo [Department of Orthopaedic Surgery, Faculty of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan); Motoi, Toru [Department of Pathology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655 (Japan)

    2003-03-01

    The clinicoradiologic and pathologic aspects of an intracortical, diaphyseal chondromyxoid fibroma of the humerus are reported. Because of the location of the lesion, the possibility of chondromyxoid fibroma was not considered radiologically. The diagnosis was made only after histologic examination of tissue obtained via an open biopsy, which led to the appropriate treatment, surgical curettage. (orig.)

  1. Peripheral ossifying fibroma

    Directory of Open Access Journals (Sweden)

    Ameet Mani

    2010-01-01

    Full Text Available The peripheral ossifying fibroma (POF is an exophytic gingival mass of fibrous connective tissue covered with a surface epithelium associated with the formation of randomly dispersed foci of a mineralized product consisting of bone, cementum-like tissue, or dystrophic calcifications having a recurrent rate of nearly 20%. It is one of the most common reactive gingival lesions, which have often been called by the generic term "epulis." This case report describes the clinical and histopathological findings of POF, its differential diagnosis, and treatment.

  2. Giant ameloblastic fibroma.

    Science.gov (United States)

    Büyükakyüz, N; Ergun, S; Soluk, M; Uyumaz, N; Tanyeri, H

    2009-03-01

    A 10 year-old male was referred to our department for a delay in the eruption of his lower canine, premolars and molars on the right side. The panoramic radiograph showed a multilocular radiolucent lesion approximately 3.5 x 7.5 cm in diameter including the right canine, first and second premolar and second mandibular molar. The lesion was clinically diagnosed as dentigerous cyst. It was enucleated via curettage of the bone bed and diagnosed as ameloblastic fibroma at the histopathological examination. After twenty-one months, radiographs showed that the surgical defect had filled with new bone.

  3. Odontogenic fibroma: An unusual presentation

    Directory of Open Access Journals (Sweden)

    Armas Jose

    2008-01-01

    Full Text Available The odontogenic fibroma is a relatively rare, slow-growing, benign odontogenic neoplasm of the jaws, with the potential to recur after excision. It may occur either intraosseously or as a localized gingival overgrowth, in which case it may be mistaken for other more common exophytic gingival lesions. This paper reinforces the importance of radiographic and histological examination for exophytic gingival lesions by describing a recurrent peripheral odontogenic fibroma, presenting in 1986, 1992, and 2003, accompanied on this last occasion by a separate but co-located, central odontogenic fibroma in the underlying alveolar process.

  4. Central cementifying fibroma of mandible

    Directory of Open Access Journals (Sweden)

    Joseph Edward

    2010-01-01

    Full Text Available Central cementifying fibroma is a rare non odontogenic tumor coming in the group of fibro osseouslesion, arising from periodontal ligament and is usually seen in tooth bearing area. It can affect boththe mandible and the maxilla, particularly the mandible. This bone tumour consists of highly cellular,fibrous tissue that contains varying amounts of calcified tissue resembling bone, cementum or both.Here we present a case of Central cementifying fibroma (recurrent in a 34 year old female.

  5. Odontogenic fibroma: An unusual presentation

    OpenAIRE

    Armas Jose; Hunter Keith; Jenkins William

    2008-01-01

    The odontogenic fibroma is a relatively rare, slow-growing, benign odontogenic neoplasm of the jaws, with the potential to recur after excision. It may occur either intraosseously or as a localized gingival overgrowth, in which case it may be mistaken for other more common exophytic gingival lesions. This paper reinforces the importance of radiographic and histological examination for exophytic gingival lesions by describing a recurrent peripheral odontogenic fibroma, presenting in 1986, 1992...

  6. Cemento-ossifying fibroma

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    Chandramani More

    2011-01-01

    Full Text Available Cemento-ossifying fibromas (COFs are benign lesions affecting the jaws and other craniofacial bones. They commonly affect adult females between the third and fourth decade of life, predominantly occurring in the premolar/molar region of the mandible. Most of the lesions typically show slow and often expansile growth, centrally within the jaw and characteristically behave in a benign form, but occasionally they may present as an aggressive gigantiform lesion. Radiographically, they appear as well-defined unilocular or multilocular intraosseous masses. The lesion is invariably encapsulated and of mixed radiolucent densities. The tumor may grow quite extensively; thus, the term "aggressive" is sometimes applied. Surgical resection is the treatment of choice. They are insensitive to radiotherapy and recurrences are uncommon. Clinical, radiographic and histopathologic features of COF and other fibro-osseous lesions are overlapping and may cause confusion in classification, diagnosis and treatment.

  7. Chondromyxoid fibroma of two thoracic vertebrae

    Energy Technology Data Exchange (ETDEWEB)

    Bruder, E. [Department of Pathology, University Hospital of Zuerich, Ch-8091 Zuerich (Switzerland); Zanetti, M. [Department of Radiology, University Clinic Balgrist, Zuerich (Switzerland); Boos, N. [Department of Orthopedic Surgery, University Clinic Balgrist, Zuerich (Switzerland); Hochstetter, A.R. von [Department of Pathology, University Hospital, Zuerich (Switzerland)

    1999-05-01

    We report on a case of chondromyxoid fibroma involving two adjacent thoracic vertebrae with features of aggressive behaviour on radiographs, CT and MRI. Histology revealed typical chondromyxoid fibroma with unusually coarse calcifications. Chondromyxoid fibroma of the spine is rare, and only 30 of these tumours have been reported so far. Involvement of two contiguous vertebral bodies by chondromyxoid fibroma, as reported here, appears exceptional. (orig.) With 5 figs., 29 refs.

  8. Chondromyxoid fibroma of the metacarpal

    Energy Technology Data Exchange (ETDEWEB)

    Hau, M.A.; Fox, E.J. [Orthopaedic Oncology Service, Massachusetts General Hospital, Boston, MA (United States); Rosenberg, A.E. [Pathology Dept., Massachusetts General Hospital, Boston, MA (United States); Mankin, H.J. [Orthopaedic Oncology Service, Massachusetts General Hospital, Boston, MA (United States); Orthopaedic Service, Massachusetts General Hospital, Boston (United States)

    2001-12-01

    This report describes a chondromyxoid fibroma which developed in the distal part of the second metacarpal of a 12-year-old girl. The tumor is rare, perhaps the rarest of all bone tumors, and the occurrence in a metacarpal of a young female is extraordinarily uncommon. (orig.)

  9. True Fibroma of Alveolar Mucosa

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    Shankargouda Patil

    2014-01-01

    Full Text Available Benign fibrous overgrowths are often found in the oral cavity, almost always being reactive/irritational in nature. However, benign mesenchymal neoplasms of the fibroblasts are extremely uncommon. Here we report a case of “True Fibroma of Alveolar Mucosa” for its rarity.

  10. Ameloblastic fibroma: an uncommon entity.

    Science.gov (United States)

    Vij, Ruchieka; Vij, Hitesh

    2013-07-09

    Ameloblastic fibroma is an uncommon mixed odontogenic tumour, which is often confused with ameloblastoma. It exhibits both epithelial and mesenchymal components with absence of any calcified dental structure. This paper presents two cases of this rare entity with detailed review of literature.

  11. Juvenile psammomatoid ossifying fibroma. Case report

    OpenAIRE

    Vahtsevanos, Konstantinos; Persephone XIROU; Giorgos BALLIS; Tsekos, Antonis; Ntomouchtsis, Aris; Alexandros VALASIDIS; Doxa MAGGOUDI

    2012-01-01

    Ossifying fibroma (OS) represents a slow growing, benign neoplasm that belongs to the greater group of fibro-osseous lesions. Based on its histological features, ossifying fibroma is divided into: a) juvenile trabecular OS and b) juvenile psammomatoid OS which affects mainly the paranasal sinuses of children and teenagers aging from 5 to 15 years.A rare case of juvenile psammomatoid ossifying fibroma in a 30 year old male patient located in the left mandibular ramus is presented. Treatment pl...

  12. Digital fibromas. Report of three cases

    Directory of Open Access Journals (Sweden)

    Patricia Chang

    2017-07-01

    Full Text Available Digital fibroma is a rare benign lesion that usually occurs during the first 2 years of life. It can be multiple, but it is usually a single lesion. If it grows large enough it can cause joint deformities or interfere with everyday activities. We report 3 cases of digital fibroma 2 in female patient and 1 in male patient due to its uncommon localization of fibromas.

  13. Central odontogenic fibroma: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Nah, Kyung Soo [School of Dentistry, Busan National University, Busan (Korea, Republic of)

    2011-06-15

    Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Here, a case of central odontogenic fibroma in a 17-year-old male is reported. Since the present case showed a multilocular radiolucency with partially ill-defined border between the right mandibular condyle and the distal root of the right mandibular third molar, differential diagnosis involved a wide range of pathosis from benign lesions like ameoloblastic fibroma and odontogenic myxoma to more aggressive lesions such as desmoplastic fibroma, juvenile aggressive fibromatosis, or fibrosarcoma.

  14. Tendon sheath fibroma in the thigh.

    Science.gov (United States)

    Moretti, Vincent M; Ashana, Adedayo O; de la Cruz, Michael; Lackman, Richard D

    2012-04-01

    Tendon sheath fibromas are rare, benign soft tissue tumors that are predominantly found in the fingers, hands, and wrists of young adult men. This article describes a tendon sheath fibroma that developed in the thigh of a 70-year-old man, the only known tendon sheath fibroma to form in this location. Similar to tendon sheath fibromas that develop elsewhere, our patient's lesion presented as a painless, slow-growing soft tissue nodule. Physical examination revealed a firm, nontender mass with no other associated signs or symptoms. Although the imaging appearance of tendon sheath fibromas varies, our patient's lesion appeared dark on T1- and bright on T2-weighted magnetic resonance imaging. It was well marginated and enhanced with contrast.Histologically, tendon sheath fibromas are composed of dense fibrocollagenous stromas with scattered spindle-shaped fibroblasts and narrow slit-like vascular spaces. Most tendon sheath fibromas can be successfully removed by marginal excision, although 24% of lesions recur. No lesions have metastasized. Our patient's tendon sheath fibroma was removed by marginal excision, and the patient remained disease free 35 months postoperatively. Despite its rarity, tendon sheath fibroma should be included in the differential diagnosis of a thigh mass on physical examination or imaging, especially if it is painless, nontender, benign appearing, and present in men.

  15. Desmoplastic Fibroma Of The Mandible

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Hyun Ju; Park, Young Hee; Choi, Karp Shik [Dept. of Oral and Maxillofacial Radiology, College of Dentistry, Kyungbook National University, Daegu (Korea, Republic of)

    1999-02-15

    Desmoplastic fibroma is a rare, benign intraosseous fibroblastic tumor, which is locally aggressive. It is osseous counterpart of soft tissue fibromatosis. The authors experienced the patient who complained persistent mouth opening limitation with mild swelling on the left mandibular angle area. After careful analysis of clinical, radiological and histopathological findings, we diagnosed as desmoplastic fibroma of the mandible.The results were as follows:1. Main clinical symptoms were mouth opening limitation which had been persistent for 9 months and mild swelling on the left mandibular angle area.2. Radiographs showed the radiolucent lesion and expansion of lingual cortex. CT finding is homogeneous soft tissue mass with expansion of left mandibularramus. Destruction of medial wall of ramus and invasion to adjacent soft tissue is also seen.3. Histopathologically, plump spindle shaped fibroblasts arranged in bundles or fascicles are observed. The cells of tumor are infiltrating into muscle fiber with destruction of bony trabeculae and merged with surrounding salivary gland.

  16. Chondromyxoid fibroma of the sacrum

    Energy Technology Data Exchange (ETDEWEB)

    Brat, H.G.; Renton, P. [Dept. of Radiology, Royal National Orthopaedic Hospital, Stanmore (United Kingdom); Sandison, A. [Dept. of Histopathology, Royal National Orthopaedic Hospital, Stanmore (United Kingdom); Cannon, S. [Dept. of Orthopaedic Surgery, Royal National Orthopaedic Hospital, Stanmore (United Kingdom)

    1999-07-01

    A 30-year-old man with a 7-month history of mild sacral pain and intermittant left sciatica was found to have an expansile lesion in the sacrum on a plain radiograph. Biopsy confirmed a chondromyxoid fibroma which was removed surgically. A 1-year follow-up showed no recurrence. The case is the fifth to be reported. Plain film and MRI appearances, histology and treatment are described. The previously reported cases are reviewed and the current literature is discussed. (orig.)

  17. Cemento-ossifying fibroma of the mandible.

    Science.gov (United States)

    Trijolet, J-P; Parmentier, J; Sury, F; Goga, D; Mejean, N; Laure, B

    2011-01-01

    Cemento-ossifying fibroma is a rare benign tumor most often discovered incidentally. A 72-year-old patient was referred for a subclinical lesion of the mandible. The orthopantomogram showed a well-circumscribed radiolucent osteolytic image, 1 cm in diameter, on the mandibular angle. On CT, the single lesion had a tissue aspect with a peripheral halo without enhancement after contrast injection. A cortical lacuna on the lingual side was noted. Surgical enucleation of the lesion was performed. The pathological examination confirmed the ossifying fibroma. Slow and progressive, cemento-ossifying fibroma is a rare benign tumor that reaches the maxilla and more frequently the mandible. The ossifying and cementifying fibromas are differentiated by their clinical, radiological, and histological findings. The authors discuss the pathogenesis and radiological signs guiding the choice of diagnostic and therapeutic methods. The treatment is surgical with an enucleation or wider resection with bone reconstruction for large fibromas. Copyright © 2010. Published by Elsevier Masson SAS.

  18. Juvenile ossifying fibroma: Psammamatoid variant

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    Shivani Aggarwal

    2012-01-01

    Full Text Available Juvenile ossifying fibroma is a rare fibro-osseous lesion containing variable amount of calcified masses, which resembles bone or cementum within a fibrocellular connective tissue stroma. It has variable clinical behavior, highly aggressive in nature including invasion and destruction of adjacent anatomic structures with a strong tendency to recur. We reported a 28-year-old female patient with a growth in the upper left vestibule region extending from canine to molar region with clinical, histopathological, and radiological features are presented. Surgical management was done, and regular follow-up was advised.

  19. Peripheral cemento-ossifying fibroma of maxilla.

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    Chatterjee, Anirban; Ajmera, Neha; Singh, Amit

    2010-07-01

    Peripheral cemento-ossifying fibroma is a reactive gingival overgrowth occurring frequently in anterior maxilla. It is a slow-growing benign tumor which may lead to pathologic migration and other periodontal problems, so it should be excised as soon as possible. The recurrence rate of peripheral cemento-ossifying fibroma is reported to be 8% to 20%, so a close postoperative follow-up is required. Herein, we are reporting a similar case of peripheral cemento-ossifying fibroma in the maxillary anterior region.

  20. Juvenile psammomatoid ossifying fibroma. Case report

    Directory of Open Access Journals (Sweden)

    Konstantinos VAHTSEVANOS

    2012-08-01

    Full Text Available Ossifying fibroma (OS represents a slow growing, benign neoplasm that belongs to the greater group of fibro-osseous lesions. Based on its histological features, ossifying fibroma is divided into: a juvenile trabecular OS and b juvenile psammomatoid OS which affects mainly the paranasal sinuses of children and teenagers aging from 5 to 15 years.A rare case of juvenile psammomatoid ossifying fibroma in a 30 year old male patient located in the left mandibular ramus is presented. Treatment plan included radical surgical excision of the lesion and restoration with autologous osteochondral graft from the 6th rib of the ipsilateral side.

  1. Multiple soft fibromas of the lid

    Directory of Open Access Journals (Sweden)

    Manuel John

    2015-01-01

    Full Text Available Fibromas are benign tumors that are composed of fibrous or connective tissue. They can grow in all organs, arising from mesenchymal tissue (a type of loose connective tissue. The term "fibroblastic" or "fibromatous" is used to describe tumors like the fibroma. This 69-year-old male presented to us with giant, multiple, very slowly progressive, painless, noninflammatory, soft, trans-illuminant, pedunculated lid swellings with a two decade history. There were no other swellings on the body. He was clinically normal on systemic examination except for the immature cataracts in both eyes. The diagnosis was confirmed on histopathology. Simple excision removed all the soft fibromas virtually leaving no scar. A review of literature world-wide using Medline Plus/PubMed revealed this to be the only reported case of multiple giant soft fibromas of the lid.

  2. Chondromyxoid fibroma of the second rib.

    Science.gov (United States)

    Long, Kristin L; Absher, Kimberly J; Draus, John M

    2013-06-01

    Chondromyxoid fibromas are benign tumors which are found most frequently in the metaphyses of long bones. They comprise less than 1% of primary bone neoplasms and display a hypermetabolic appearance on PET imaging. Oftentimes, they are misdiagnosed as chondrosarcomas and are excised due to concern for malignancy. We present a case of a condromyxoid fibroma originating from the second rib of a 15-year-old girl.

  3. Omental fibroma: CT and US findings

    Energy Technology Data Exchange (ETDEWEB)

    Paksoy, Y.; Acikgoezoglu, S.; Oedev, K. [Department of Radiology, Selcuk Univ., Konya (Turkey); Sahin, M. [Department of General Surgery, Selcuk Univ., Konya (Turkey); Oemeroglu, E. [Department of Pathology, Selcuk Univ., Konya (Turkey)

    1998-10-01

    The US, CT, and X-ray findings in a patient with omental fibroma of the lesser omentum are described. Ultrasound showed a solid mass with cystic areas in the central region. At CT the lesion showed peripheral enhancement and central hypodensity. On X-ray studies with barium, there was border distortion in the lesser curvature of the stomach. The mass was resected surgically. A pathologic diagnosis of fibroma was confirmed. (orig.) (orig.) With 5 figs., 8 refs.

  4. Central odontogenic fibroma of the simple type

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    Hwang, Eui Hwan; Lee, Sang Rae [Department of Oral and Maxillofacial Radiology, College of Dentistry, Kyung Hee University, Seoul (Korea, Republic of)

    2002-12-15

    The central odontogenic fibroma is a rare benign neoplasm, and considered to be derived from the mesenchymal tissue of dental origin. It is a poorly defined tumor of the jawbones which has only been infrequently reported in the literature. We report a histologically proven case of simple-type central odontogenic fibroma, which affected the left canine-premolar region of the maxilla in a 52-year-old woman.

  5. Peripheral odontogenic fibroma. Report of 5 cases.

    Science.gov (United States)

    Buchner, A

    1989-04-01

    The peripheral odontogenic fibroma (WHO type) is a relatively rare, benign, unencapsulated, exophytic gingival mass of fibrous connective tissue. Odontogenic epithelium is found within the gingival mass, but usually appears to play a minor role when compared to the fibrous component. According to the present concept, cases reported in the literature under the terms "odontogenic gingival epithelial harmartoma" "hamartoma of the dental lamina" and "peripheral ameloblastic fibrodentinoma" are actually examples of peripheral odontogenic fibroma. Review of the literature revealed only 30 acceptable cases that fit the present concept of peripheral odontogenic fibroma. Because of the paucity of reported cases, the histomorphological spectrum and the clinical features of this lesion have not yet been fully established. This article presents five new cases of peripheral odontogenic fibroma. The connective tissue ranged from markedly cellular to relatively acellular well collagenized. Islands and strands of epithelium were present in all five cases: in four they were scanty and in one abundant. A matrix of mineralized material was present in four cases. The peripheral odontogenic fibroma must be differentiated histologically from peripheral ossifying fibroma, which is a reactive lesion, and from the peripheral ameloblastoma and the calcifying epithelial odontogenic tumour.

  6. Tendon sheath fibroma of the medial canthal tendon.

    Science.gov (United States)

    Andrew, Nicholas; Dodd, Tom; Selva, Dinesh; Davis, Garry

    2013-01-01

    Fibromas of the tendon sheath are slow-growing, benign tumors most commonly found on the hands and wrist. A fibroma of the tendon sheath arising from the medial canthal tendon presented as an enlarging nodule that had been present for 40 years. The fibroma was identified by microscopy and immunohistochemistry, and surgical resection appears to have been curative.

  7. Soft tissue chondromyxoid fibroma of the foot: sonographic findings.

    Science.gov (United States)

    Kim, Hye Rin; Lee, Sang Min; Ha, Doo Hoe; Kang, Haeyoun; Rho, Ji Young

    2012-02-01

    Chondromyxoid fibroma is a rare benign bone tumor, which represents less than 1% of primary bone tumors. However, chondromyxoid fibroma developing in the soft tissue is extremely rare. We report the sonographic findings in a case of soft tissue chondromyxoid fibroma in the foot confirmed pathologically.

  8. Fibroma periférico odontogénico: A propósito de un caso Peripheral odontogenic fibroma: A case report

    OpenAIRE

    M. Rebolledo Cobos; O. Cantillo Payares; A. Díaz Caballero

    2010-01-01

    El fibroma periférico odontogénico es una lesión tumoral de la submucosa oral o del ligamento periodontal causado por irritación crónica como traumatismos locales, cuerpos extraños y cálculo o ciertos factores que transforman el tejido conectivo de las mucosas en tejido fibroso. Es de crecimiento lento, asintomático y en ocasiones involuciona cuando se eliminan los factores causales. El tratamiento consta de escisión quirúrgica y curetaje de la base de la lesión para evitar recurrencias. Se p...

  9. Peripheral cemento-ossifying fibroma: case series literature review.

    Science.gov (United States)

    Verma, Esha; Chakki, Arunkumar Bhimashankar; Nagaral, Sharanbasappa Chandrashekar; Ganji, Kiran Kumar

    2013-01-01

    THE CONCEPT OF FIBROOSSEOUS LESIONS OF BONE HAS EVOLVED OVER THE LAST SEVERAL DECADES AND NOW INCLUDES TWO MAJOR ENTITIES: fibrous dysplasia and ossifying fibroma. Peripheral cemento-ossifying fibroma is a relatively rare tumour classified between fibroosseous lesions. It predominantly affects adolescents and young adults, with peak prevalence between 10 and 19 yrs. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion regarding terminology and the criteria for its diagnosis. The cemento-ossifying fibroma is odontogenic in origin, whereas ossifying fibroma is of bony origin. Lesions histologically similar to peripheral ossifying fibroma have been given various names in existing literature. Therefore, we present and discuss in this paper a series of cases of peripheral cemento-ossifying fibroma emphasizing the differential diagnosis.

  10. Cutaneous fibroma in the roe deer (Capreolus capreolus

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    Kureljušić Branislav

    2009-01-01

    Full Text Available Fibromas present very frequent skin neoplasms in different species of wild game of the family Cervidae. Viral etiology of skin neoplasms was proven in certain species of wild game from this family, with the most frequent diagnoses being: fibromas, ossifying fibromas, fibrosarcomas, multiple neurofibromatosis, fibropapillomas, and papillomas. The diagnozed tumor in the roe deer had the histological characteristics of a polimorphous fibroblast, which is not the case with domestic animals. This finding can be considered as a characteristic of fibromas in animals of the family Cervidae. Solitary fibroma or multiple fibroma (fibromatosis does not present a significant cause of deer deaths, but they cause concern among hunters who are in direct contact with them. Although fibromas do not lead to spoilage of game meat, they are esthetically repellent and people are reluctant to consume meat of such game.

  11. [Clinical aspects and diagnosis of pleural fibromas].

    Science.gov (United States)

    Smati, B; Djilani, H; Boudaya, M S; Ghrib, B S; Mestiri, T; Mezni, F; Bouacha, H; Kilani, T

    2005-12-01

    Pleural fibromas are rare malignant or benign tumors requiring pathology study for certain diagnosis. From January 1985 to January 2001, 7 patients underwent surgery in our unit for pleural fibroma: 4 females and 3 males, mean age 60 years. The inaugural symptoms were chest pain (3 patients), dyspnea (2 patients), joint pain in a patient with Pierre-Marie pneumonic hypertrophic osteo-arthropathy, and acute hypoglycemia. Radiological investigations were decisive in orienting the diagnosis (chest X-ray, ultrasound, computed tomography and MRI). Surgical resection and pathological study of the surgical specimen is required to confirm the diagnosis. Patients should be carefully followed due to the risk of malignant recurrence.

  12. Cemento-ossifying fibroma of the jaw.

    Science.gov (United States)

    Katti, Girish; Khan, Mohammed Munnawarulla; Chaubey, Shashi Shanker; Amena, Mehroz

    2016-05-12

    Cemento-ossifying fibroma is a benign growth, considered to originate from the periodontal ligament. It is often encapsulated and predominantly located in the mandible, and presents as a slow-growing lesion, but may cause deformity if left untreated. The definitive diagnosis of these lesions requires integration of its clinical, radiological and histological features. We present a case of cemento-ossifying fibroma in relation to the lower left one-third of the face, and its management. 2016 BMJ Publishing Group Ltd.

  13. Calcifying aponeurotic fibroma of the distal phalanx.

    Science.gov (United States)

    Schonauer, Fabrizio; Avvedimento, Stefano; Molea, Guido

    2013-02-01

    Calcifying aponeurotic fibroma is a rare benign soft tissue tumor that primarily occurs on the distal portion of the extremities of children and adolescents. It appears like a firm, painless and slowly growing mass with high local recurrence rates. The lesion has characteristic histological features with areas of proliferative plumps of fibroblasts, chondrocytes and foci of calcification. We present a case of calcifying aponeurotic fibroma of the sub-ungual area of the index finger distal phalanx with bone erosion, surgically treated. A 2 year follow up showed satisfactory functional result and no evidence of recurrence.

  14. Meningeal fibroma: a rare meningioma mimic.

    Science.gov (United States)

    Kakkar, Aanchal; Sharma, Mehar C; Goyal, Nishant; Sarkar, Chitra; Suri, Vaishali; Garg, Ajay; Kale, Shashank S; Suri, Ashish

    2014-08-01

    Meningeal fibromas are rare intracranial tumors that mimic meningiomas radiologically as well as histologically. The authors report 2 cases of meningeal fibroma with detailed clinical, radiological, histopathological, and immunohistochemical features, and discuss the differential diagnosis of this entity. Knowledge of this rare tumor is essential for pathologists to be able distinguish it from more common meningeal tumors, especially in younger patients. This knowledge is also essential for neurosurgeons, as incomplete resection may lead to tumor recurrence, and such patients require close follow-up.

  15. Desmoplastic fibroma of bone: MRI features

    Energy Technology Data Exchange (ETDEWEB)

    Vanhoenacker, F.M. [Department of Radiology, University Hospital Antwerp, Edegem (Belgium); Department of Radiology, AZ Sint Maarten, Duffel (Belgium); Hauben, E.; Van Marck, E. [Department of Pathology, University Hospital Antwerp, Edegem (Belgium); De Beuckeleer, L.H.; De Schepper, A.M. [Department of Radiology, University Hospital Antwerp, Edegem (Belgium); Willemen, D. [Department of Orthopaedic Surgery, AZ Sint Maarten, Duffel (Belgium)

    2000-03-30

    Desmoplastic fibroma of bone is a very rare benign tumor, which may be locally aggressive. In contrast to the well-documented radiological appearance, the literature on MR imaging features of this tumor is scarce. The MR imaging characteristics in our case are compared to those previously reported. Although there is a considerable overlap in the MR imaging features with other bone tumors, an interesting MR feature of desmoplastic fibroma is the presence of low to intermediate signal intensity foci on T2-weighted images, which radiographically does not correspond to calcifications. This feature may help narrow the differential diagnosis. (orig.)

  16. [Maxillary ameloblastic fibroma: a case report].

    Science.gov (United States)

    Wang, Hongming; Xue, Weishuang; Yan, Aihui

    2013-12-01

    Ameloblastic fibroma (AF) is a benign tumor, it is a true mixed tumor composed of neoplastic epithelium and mesenchymal. This tumor is rare, and it almost arises in the mandible. A 22-years old female patient referred AF in the maxillary was present. The tumor was asymptomatic, except the right facial bulge. The radiograph showed a well-circumscribed neoplasm with several low density cysts involving the right maxillary and ethmoid. The lesion was enucleated and the material was sent for histopathologic examination. Microscopically, it was composed epithelium and mesenchymal with histopathological diagnosis of ameloblastic fibroma.

  17. Maxillary ameloblastic fibroma in a dog.

    Science.gov (United States)

    Miles, C R; Bell, C M; Pinkerton, M E; Soukup, J W

    2011-07-01

    A 4-year-old spayed female Golden Retriever was presented for evaluation of a rostral maxillary gingival mass. An en bloc resection was performed after histologic diagnosis of ameloblastic fibroma from an incisional biopsy specimen. Histologically, the tumor was composed of (1) poorly differentiated vimentin-positive mesenchymal cells that surrounded islands and (2) thin anastomosing trabeculae of odontogenic epithelium that variably coexpressed pancytokeratin and vimentin. To the authors' knowledge, this is the first report of ameloblastic fibroma in a dog. The clinical, radiographic, and histologic findings in this case are compared to those in other domestic animals and humans. © The Authors 2011

  18. Peripheral Ameloblastic Fibroma: Report of a Rare Case

    Directory of Open Access Journals (Sweden)

    Mahsa Kalantari

    2016-12-01

    Full Text Available Ameloblastic fibroma is a rare mixed odontogenic tumor mostly occurring in the posterior region of the mandible. The peripheral variant is very rare and to the best of our knowledge, only three cases have been reported in the English literature. In this report, we describe a case of peripheral ameloblastic fibroma in a 54-year-old woman with two years of follow-up. Keywords ● Ameloblastic fibroma ● Gingiva ● Peripheral

  19. Bilateral ovarian fibromas in a young patient: A rare occurrence

    Directory of Open Access Journals (Sweden)

    Shailja Puri Wahal

    2014-01-01

    Full Text Available Ovarian fibroma accounts for 4% of all ovarian tumors. The mean age of presentation is 48 years. Nearly 10% cases are seen in age less than 30 years. Bilateral fibromas occur in association with nevoid basal cell carcinoma syndrome (gorlin syndrome. We report a case of bilateral fibromas in a 22-year-old female patient with ascites without any evidence of nevoid basal cell carcinoma syndrome.

  20. Scalp fibroma: a rare cutaneous manifestation of tuberous sclerosis.

    Science.gov (United States)

    Sharma, Bhawna; Prakash, Swayam; Sannegowda, Raghavendra Bakki; Panagariya, Ashok

    2014-04-19

    We report a case of a 23-year-old woman with a history of generalised tonic-clonic seizures, reddish brown maculopapular swelling over the face and an enlarging swelling over the scalp. Physical examinations revealed angiofibroma of the face and other typical cutaneous lesions of tuberous sclerosis, for example, shagreen patch and periungual fibroma. Scalp swelling was labelled as fibroma by dermatologists, which was further supported by the histopathological findings. Fibroma of the face is one of the commonest lesions, however, fibroma of the scalp is a rarely described entity.

  1. Palatal Fibroma - A Case-report

    Directory of Open Access Journals (Sweden)

    Farooque Khan

    2016-03-01

    Full Text Available Fibroma is a benign tumor of fibrous connective tissue. Fibromas represent inflammatory state rather than neoplastic conditions, which  are mostly sessile or slightly pendunculated with a smooth contour, pale pink and are  firm in consistency, which commonly  occurs on gingiva, tongue, buccal mucosa and palate. Cinical, radiographic and histopathologic data combined with surgical findings are though essential, but it requires further studies to determine the exact nature of such fibromatous lesions. A multidisciplinary approach is needed in the management of ffibrtous lesions, so as to minimize its recurrence and to improve the quality of life, providing better  functioning and esthetics.JCMS Nepal. 2016;12(1:36-9.

  2. Peripheral ossifying fibroma. A case report

    Directory of Open Access Journals (Sweden)

    Karen Nair Vallejos Duarte

    2015-12-01

    Full Text Available Introduction: Peripheral ossifying fibroma, a pseudotumoral injury, considered within simple reactive hyperplasia, which generally have a definite cause and are often reversible. Objective: To present a case of an injury to a patient, which manifested as radiolucent lesion, asymptomatic, whose differential diagnosis based on clinical manifestations and conventional radiographic study is controversial. Case Description: A case is presented in a male patient with 51-year-old with a lesion in the maxillary incisor-canine area, aspects of which were suggestive of granuloma telangiectásico. Previous clinical and radiographic evaluation, the patient underwent surgical resection of the lesion and was sent for histopathological examination, showing compact osteoid material revealing the peripheral final diagnosis, ossifying fibroma. Conclusion: The professional dentist must have knowledge and ability to clinical management of oral pathologies, to make a correct diagnosis and treatment, for it is essential to perform a biopsy, to avoid possible disputes between the clinical and histological diagnosis.

  3. Maxillary ameloblastic fibroma: a case report.

    Science.gov (United States)

    Costa, Daniela Otero Pereira da; Alves, Adriana Terezinha Neves Novellino; Calasans-Maia, Mônica Diuna; Cruz, Ricardo Lopes da; Lourenço, Simone de Queiroz Chaves

    2011-01-01

    Ameloblastic fibroma is a relatively rare benign odontogenic tumor in which both the epithelial and ectomesenchymal components are neoplastic. An 8-year-old Caucasian boy was referred to the dentist for evaluation of failed eruption of the maxillary left first molar. The panoramic radiograph showed a well-circumscribed unilocular radiolucency involving an unerupted maxillary left first permanent molar. The lesion was enucleated and the material was sent for histopathologic examination. Microscopically, it was composed by cords and islands of odontogenic epithelium in a myxoid cell-rich stroma that closely resemble the dental papilla with histopathological diagnosis of ameloblastic fibroma. After 24 months of follow-up no recurrence was observed and the maxillary left first molar erupted spontaneously through the buccal mucosa and was aligned with a fixed orthodontic appliance. This case emphasized the importance of careful differential diagnosis of intraosseous oral lesions and reported a rarity of the lesion and its atypical location.

  4. Juvenile ossifying fibroma: CT and MR findings

    Energy Technology Data Exchange (ETDEWEB)

    Khoury, Nabil J.; Naffaa, Lena N.; Haddad, Maurice C. [Department of Diagnostic Radiology, American University of Beirut Medical Center, P.O. Box 113-6044, Beirut (Lebanon); Shabb, Nina S. [Department of Pathology, American University of Beirut - Medical Center, P.O. Box 113-6044, Beirut (Lebanon)

    2002-07-01

    We describe the CT findings in four patients and the MR imaging in one patient with juvenile ossifying fibroma. Three lesions involved the maxillary sinus and extended to the surrounding structures; one lesion was confined to the maxillary bone. CT scan revealed well-defined, expansile lesions with variable amount of calcifications. On MRI one lesion had intermediate signal intensity with significant contrast enhancement. (orig.)

  5. Surgical resection of a giant cardiac fibroma.

    Science.gov (United States)

    Stamp, Nikki L; Larbalestier, Robert I

    2016-05-01

    A 42-year-old woman presented to a regional hospital emergency room with palpitations and was found to be in ventricular tachycardia. Chest radiography demonstrated a massively enlarged cardiac silhouette. Echocardiography and cardiac magnetic resonance imaging demonstrated a mass within the left ventricular free wall, consistent with a cardiac fibroma. The patient proceeded to have surgical resection of the mass. Left ventricular function was preserved postoperatively.

  6. Peripheral ossifying fibroma. A case report

    OpenAIRE

    Vallejos Duarte, Karen Nair; Jacquett Toledo, Ninfa Lucia

    2015-01-01

    Introduction: Peripheral ossifying fibroma, a pseudotumoral injury, considered within simple reactive hyperplasia, which generally have a definite cause and are often reversible. Objective: To present a case of an injury to a patient, which manifested as radiolucent lesion, asymptomatic, whose differential diagnosis based on clinical manifestations and conventional radiographic study is controversial. Case Description: A case is presented in a male patient with 51-year-old with a lesion in th...

  7. Imaging findings of desmoplastic fibroma rarely involoving the clavicle: Case report

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dong Min; Juhng, Seon Kwan; Sohn, Young Jun; Kim, Hun Soo [Wonkwang University School of Medicine and Hospital, Iksan (Korea, Republic of)

    2014-02-15

    Desmoplastic fibroma of bone is a rare locally aggressive, but non-metastatic tumor. In this case report, we present a desmoplastic fibroma in an unusual location, the clavicle. Desmoplastic fibroma involving the clavicle is extremely rare, with only 2 reported cases before 1985. We report the imaging findings of a desmoplastic fibroma of the clavicle with a review of the relevant literature.

  8. Cemento-ossifying fibroma of the maxilla.

    Science.gov (United States)

    Al-Shaham, A A; Samher, A A

    2010-12-01

    Despite the fact that cemento-ossifying fibromas of the maxilla may be quite large and locally aggressive, en-bloc excision is achieved by gentle blunt dissection, with the whole tumour mass peeled out from the adjacent structures. Until recently different fibro-osseous tumours that contained cementum were classified together as "cementomas". In 1992 The World Health Organization adopted a new classification that included these fibromas as benign osseous tumours. While such tumours of the mandible are common, those of the maxilla are rare. They are growth products of periodontal membrane remnant. The triggering mechanism in the formation of cementum outside the periodontal membrane remains unclear. We present a 35-year-old woman who had a giant expanding lobular mass in the right maxilla of 5 years duration. She had visual disturbances and nasal obstruction, and was treated successfully by surgical en-bloc resection of the tumour through an infraorbital transverse incision. The differential diagnosis included fibrous dysplasia, osteoid osteoma, osteoblastoma, chronic sclerosing osteomyelitis, ameloblastoma, squamous cell carcinoma of the maxillary sinus, calcifying epithelial odontogenic tumour (Pindborg tumour) and calcifying odontogenic cyst (Gorlin cyst). Histopathological examination confirmed a cemento-ossifying fibroma.

  9. Chondromyxoid fibroma of the seventh cervical vertebra

    Directory of Open Access Journals (Sweden)

    Jonathan Ashish

    2008-01-01

    Full Text Available Chondromyxoid fibroma is a rare benign bone tumor representing less than 0.5% of all bone tumors. It commonly involves the long tubular bones. Involvement of the spine is rare. A 35-year-old man presented with history of neck pain, restriction of neck movements, pain and numbness along the medial aspect of the left forearm and weakness with wasting of the left hand. A presumptive diagnosis of a bony tumor such as an aneurysmal bone cyst or a giant cell tumor involving the seventh vertebral body was made on plain X-rays, MRI and bone scan. He underwent C7 central corpectomy, incomplete intralesional curettage with iliac bone grafting and C6 to T1 interspinous wiring. The histological diagnosis was chondromyxoid fibroma. On eight years′ follow-up, CT scan showed no progression of the tumor with good alignment and fusion of the graft at the site of the corpectomy. The authors conclude that corpectomy and iliac bone grafting for chondromyxoid fibroma has a good outcome on long-term follow-up.

  10. Bilateral ovarian fibroma associated with Gorlin syndrome

    Directory of Open Access Journals (Sweden)

    Shahnaz Aram

    2009-02-01

    Full Text Available

    • Gorlin syndrome (GS, also known as nevoid basal cell carcinoma syndrome (NBCCS, is a rare inherited multisystem disorder. This paper presents a 22-years-old Iranian woman with this syndrome whose past history was multiple keratocysts of maxillary bone. She was referred to gynecology clinic with the chief complaint of irregular menses and vaginal spotting. On examination, frontal bossing and hypertelorism were detected. Physical examination of genitalia disclosed bilateral adnexal masses. Pelvic ultrasound showed two solid, echogenous and calcified masses measuring 100*50*10 & 60*50*45 mm in the left and right ovaries, respectively. The patient underwent right oophorectomy and ovarian mass resection with preservation of intact ovarian tissue on the left side. On frozen and permanent histological sections, bilateral and calcified ovarian fibromas were diagnosed. Surprisingly, during the last follow-up one year after the surgery, we found that our patient was expecting a baby. It can be concluded that in the presence of bilateral and calcified ovarian fibromas, the possibility of GS should be considered. Accurate diagnosis is only possible with close attention to the familial and past medical history and physical examination. In these patients, careful follow up for detecting malignancies and other complications is highly recommended.
    • KEY WORDS: Gorlin syndrome, ovarian fibroma, multiple keratocysts.

  11. [A case report of giant cemento-ossifying fibroma].

    Science.gov (United States)

    Lu, Run; Liang, Wen-Wu; Yang, Zhan; Liu, Chun-Hai; Zhao, Yue-Tao

    2010-12-01

    Cemento-ossifying fibroma is a rare benign tumor from periodontium, which usually occurs in mandible body and mandible ramus. It consists of collagen fibrils, fibroblast, and cementoblast. This article reported a case of giant cemento-ossifying fibroma and discussed the clinical features and treatment.

  12. Juvenile psammomatoid ossifying fibroma: An unusual case report

    Directory of Open Access Journals (Sweden)

    Nidhi Yadav

    2013-01-01

    Full Text Available Ossifying fibromas are well-demarcated benign fibro-osseous tumors of craniofacial skeleton most often in the jaws. It has two types, conventional and juvenile ossifying fibroma (JOF. JOF is considered a separate entity from ossifying fibroma due to its locally aggressive behavior and tendency to occur at a young age. Two subtypes of JOF, i.e., juvenile psammomatoid ossifying fibroma (JPOF and juvenile trabecular ossifying fibroma have been identified on the basis of histology 70% of the JPOF occur in the paranasal sinuses, 20% in the maxilla and only 10% in the mandible. Here, we report a case of JPOF in a 14-year-old girl causing an asymptomatic expansile swelling in the right mandibular posterior region, which is a rare site for this tumor.

  13. Dev hücreli fibroma ile ilgili olgu raporu ve güncelleme

    OpenAIRE

    Madi, Medhini; Ram Shetty, Shishir; Subhas G Babu; Achalli, Sonika

    2014-01-01

    The giant cell fibroma is a fibrous tumour with a distinctive clinicopathologic features which sets it apart from a conventional fibroma. It represents approximately 2% to 5% of all oral fibrous proliferations submitted for biopsy and is found predominantly in Caucasians and rarely in other races. Most often giant cell fibroma is mistaken for papilloma because of its papillary surface or fibroma because of its fibrous or elastic nature. Here, we report a case of giant cell fibroma, in the reg...

  14. Differentiation between ovarian fibroma and subserosal leiomyoma by MR imaging

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Sang Yeol; Lee, Jun Woo; Kim, Chang Won; Kim, Yong Woo; Lee, Suck Hong [College of Medicine, Pusan National University, Pusan (Korea, Republic of)

    2000-01-01

    To evaluate the findings and differential points of ovarian fibroma and subserosal leiomyoma, as seen on MR images. The MRimaging findings of 31 surgically confirmed cases of ovarian fibroma (n=3D6) and subserosal leiomyoma (n=3D25; 28) lesions were evaluated. Multiplanar T1-T2-weighted and postcontrast T1-weighted images were obtained using a 1.5T MR unit, and histologic examination was also performed. The MR findings were analyzed in terms of signal intensity, the presence and definition of margin, the histologic finding of hyperintense lesion on T2-weighted images, the presence of the bridging vessel sign, degree of enhancement, and the presence of ipsilateral ovary and ascites. Both fibromas and leiomyomas showed hypo- or isointensity compared with uterine myometrium on T1-weighted images and compared with skeletal muscle on T2-weighted images. The latter revealed intratumoral hyperintense lesions in most cases of ovarian fibroma and subserosal leiomyoma. Three of four ovarian fibromas had a well defined margin after cystic change, but in 24 of 26 subserosal leiomyomas the margin was ill defined. The 'bridging vessel sign' was visible only in subserosal leiomyomas (22/28), and in all cases the enhancement of ovarian fibromas were less than that of myomtetrium. Subserosal leiomyomas (12/28), seen on enhancement as isointense or hyperintense to myometrium, showed a greater degree of enhancement than ovarian fibromas (0/6). Ipsilateral ovary was rarely seen in ovarian fibromas (1/6), but commonly seen in subserosal leiomyomas (20/250. Ascites was present in one case of ovarian fibroma. A defined margin of an intratumoral hyperintense lesion, as seen on T2-weighted images, and the presence or absence of the 'bridging vessel sign' and ipsilateral ovary are useful signs when differentiating between ovarian fibromas and subserosal leiomyomas. (author)

  15. Fibroma periférico odontogénico: A propósito de un caso Peripheral odontogenic fibroma: A case report

    Directory of Open Access Journals (Sweden)

    M. Rebolledo Cobos

    2010-08-01

    Full Text Available El fibroma periférico odontogénico es una lesión tumoral de la submucosa oral o del ligamento periodontal causado por irritación crónica como traumatismos locales, cuerpos extraños y cálculo o ciertos factores que transforman el tejido conectivo de las mucosas en tejido fibroso. Es de crecimiento lento, asintomático y en ocasiones involuciona cuando se eliminan los factores causales. El tratamiento consta de escisión quirúrgica y curetaje de la base de la lesión para evitar recurrencias. Se presenta un caso clínico en el servicio de Estomatología y cirugía oral de una Universidad en Cartagena Colombia, de un paciente de 36 años de edad, masculino y sistémicamente sano con impresión clínica de fibroma periférico odontogénico ubicado en el tercio anterior derecho de paladar duro, ulcerado y asintomático de un año de evolución. Se ejecutan diversos estudios paraclínicos como radiografías panorámicas, periapicales y oclusales para descartar afección a estructuras óseas. Previo a la firma de un consentimiento informado se realizó procedimiento quirúrgico que constó de la escisión quirúrgica de la lesión para posterior análisis histopatológico que confirmó el diagnostico.The peripheral odontogenic fibroma is a tumor of the oral submucosa, or periodontal ligament caused by chronic irritation, local trauma, dental calculus foreign agents or certain agents that may transform the connective tissue of the mucous membranes in fibrous tissue. It is like slow growing, asymptomatic and sometimes regress when the etiologic factors are eliminated. Treatment consists of surgical excision and curettage of the base of the lesion to prevent recurrence. In this paper is presented a clinical case in the service of oral surgery and stomatology of a University in Cartagena Colombia, in a 36 years old patient, male and systemically healthy with clinical impression of peripheral odontogenic fibroma located in the anterior third of

  16. Recurrent peripheral cemento-ossifying fibroma.

    Science.gov (United States)

    Pereira, Treville; Shetty, Subraj; Shetty, Arvind; Pereira, Svylvy

    2015-01-01

    Peripheral cement-ossifying fibroma (PCOF) is a rare osteogenic neoplasm that ordinarily presents as an epulis-like growth. It frequently occurs in maxillary anterior region in teenagers and young adults. We report a case of PCOF in a 42-year-old male, which was previously surgically excised and recurred after a period of 2 years. PCOF should be considered in the differential diagnosis of reactive hyperplastic lesions originating from gingiva. Hence, early diagnosis with proper surgical excision and aggressive curettage of the adjacent tissues is essential for prevention of recurrence.

  17. Central Odontogenic Fibroma of the Mandible

    Directory of Open Access Journals (Sweden)

    Saeedeh Khajeh Ahmadi

    2013-01-01

    Full Text Available A 16-years-old female patient with painless swelling of the right side of mandible is described. She noticed the swelling from two years ago, without painful symptoms. Axial CT imaging showed buccal expansion with intact buccal and lingual cortical bone. The report of incisional biopsy was central odontogenic fibroma. Under general anesthesia the lesion was removed after ostectomy of buccal cortical plate and inferior alveolar nerve preserved. Three-year follow-up after tumor excision relieved no recurrence.

  18. Pediatric Chondromyxoid Fibroma-Like Osteosarcoma.

    Science.gov (United States)

    Stark, Matthew; Heinrich, Stephen D; Sivashanmugam, Raju; Mackey, Dane; Wasilewska, Ewa; Craver, Randall

    2017-04-01

    Chondromyxoid fibroma-like osteosarcoma (CMF-OS) is a low-grade osteosarcoma, often misdiagnosed on initial biopsy as a benign lesion, with five cases previously described. We report a 13-year-old male with an intramedullary lytic CMF-OS of the right tibial proximal metaphysis with cortical destruction and soft tissue extension. Diagnosis was based on malignant new bone formation, increased mitotic figures, lamellar bone permeation with bony destruction, and correlation with imaging studies. There were no metastasis at presentation and the tumor showed good response to standard chemotherapy with >95% necrosis.

  19. Cranial juvenile psammomatoid ossifying fibroma: case report.

    Science.gov (United States)

    Barrena López, Cristina; Bollar Zabala, Alicia; Úrculo Bareño, Enrique

    2016-03-01

    Juvenile psammomatoid ossifying fibroma (JPOF) is a fibroosseous tumor that arises in the craniofacial bones in young people. This lesion usually originates in the jaw, orbit, and ethmoid complex but can also be associated with the skull base and calvaria. Diagnosis must be made based on observing typical radiological and histopathological features. Although JPOF is a rare pathological entity, neurosurgeons must consider this odontogenic lesion in the differential diagnosis of skull masses given the lesion's aggressive behavior and locally invasive growth. Treatment must be gross-total resection. In the following article, the authors present a case of cranial JPOF and discuss various aspects of this entity.

  20. Treatment of a recurrent ameloblastic fibroma.

    Science.gov (United States)

    Manzon, Steven; Philbert, Rawle F; Bush, Benjamin F; Zola, Malcolm B; Solomon, Marshall

    2015-01-01

    Ameloblastic fibroma (AF), a slow-growing, benign tumor of odontogenic origin, represents 2% of all odontogenic tumors. Jaw expansion is among the most common symptoms, with diagnosis often made through routine radiographs. AFs have a recurrence rate of 18% to 43.5% after conservative enucleation. Long-term follow-up by both the surgeon and referring dentist is recommended, since recurrence may be due to regrowth of residual tumor undergoing malignant transformation. Aggressive management is recommended for local tumor recurrence. En bloc excision with bone grafting, followed by implant reconstruction, can be curative and preservative of function. Treatment of a recurrent AF is described.

  1. Ameloblastic fibroma of the maxillary sinus.

    Science.gov (United States)

    Pereira, Kevin D; Bennett, Kristin M; Elkins, Tina P; Qu, Zhenhong

    2004-11-01

    Ameloblastic fibroma is a rare true mixed tumor of odontogenic origin with both mesenchymal and ectodermal components. It usually arises from the mandibular dentition and presents in the second decade of life. It is a benign slow growing tumor that is less infiltrative than an ameloblastoma but tends to expand bone. It infrequently involves the maxilla and hence the management of these tumors in that region is controversial. The goal of therapy is to avoid cosmetic deformity without compromising on tumor eradication. We present the tenth reported case of this type of tumor in the maxilla, and the second one in an infant.

  2. Bimaxillary presentation of central ossifying fibroma: a unique aggressive entity

    Science.gov (United States)

    Desai, Kiran; Gupta, Kavita; Manjunatha, B S; Palan, Soniya

    2013-01-01

    Central ossifying fibroma is a benign neoplasm, having slow growing nature. Some rare lesions show very aggressive nature, multifocal appearance and reach up to a very massive size. So, these kinds of cases require special attention for their treatment. A unique case of central ossifying fibroma with aggressive nature, multifocal appearance is reported. This case shows growth both in maxilla and mandible with maxillary lesion massive in size involving maxillary sinus. There have not been any such cases reported so far in the literature showing bimaxillary growth of ossifying fibroma. PMID:23774709

  3. Collagenous Fibroma (Desmoplastic Fibroblastoma) of the Finger: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Sung, Young Jae; Koo, Joon Bum [Dongguk University Ilsan Hospital, Dongguk University College of Medicine, Goyang (Korea, Republic of)

    2011-01-15

    Collagenous fibroma is a recently described, rare, benign, soft tissue tumor that arises in the subcutaneous tissue or muscle. We report here on a case of a collagenous fibroma of the finger. A 54-year-old man was admitted to our hospital with a painless, slow-growing mass in the finger. On magnetic resonance imaging (MRI), the mass showed iso-signal intensity on the T1-weighted image, low signal intensity on the T2- weighted image and focal non-enhancing areas on the contrast-enhanced T1-weighted image. The lesion was totally removed by surgical excision and it was pathologically confirmed to collagenous fibroma

  4. Calcifying aponeurotic fibroma: Case report with radiographic and MR features

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ok Hwa; Kim, Yeon Mee [Inje University College of Medicine, Haeundae Paik Hospital, Busan (Korea, Republic of)

    2014-02-15

    Calcifying aponeurotic fibroma is a rare, benign fibroblastic tumor. The lesion has a propensity for local invasion and a high recurrent rate. Therefore, accurate preoperative diagnosis and complete excision are important to prevent the recurrence of the tumor after surgical removal. However, radiographic and magnetic resonance imaging findings of calcifying aponeurotic fibroma have been extremely rarely described in the radiology literature. Thus, we report a rare case of calcifying aponeurotic fibroma affecting the dorsal wrist in a 67-year-old man, describe radiographic and MR findings, and discuss the differential diagnosis of the tumor.

  5. Calcifying aponeurotic fibroma: case report with radiographic and MR features.

    Science.gov (United States)

    Kim, Ok Hwa; Kim, Yeon Mee

    2014-01-01

    Calcifying aponeurotic fibroma is a rare, benign fibroblastic tumor. The lesion has a propensity for local invasion and a high recurrent rate. Therefore, accurate preoperative diagnosis and complete excision are important to prevent the recurrence of the tumor after surgical removal. However, radiographic and magnetic resonance imaging findings of calcifying aponeurotic fibroma have been extremely rarely described in the radiology literature. Thus, we report a rare case of calcifying aponeurotic fibroma affecting the dorsal wrist in a 67-year-old man, describe radiographic and MR findings, and discuss the differential diagnosis of the tumor.

  6. Ameloblastic fibromas and related tumors in cattle.

    Science.gov (United States)

    Gardner, D G

    1996-03-01

    This article concerns rare odontogenic tumors that occur predominantly in the mandibular incisor region of young cattle and which have often in the past been referred to as ameloblastomas, or as the outdated synonym, adamantinoma. Twenty-two examples from the literature and two new ones were studied. Six consisted of epithelial islands which resembled those of ameloblastoma but which were located within a cellular fibrous connective tissue that was the second component of the tumor; these mixed odontogenic tumors therefore represented ameloblastic fibromas, not ameloblastomas. Eight consisted of a combination of ameloblastic fibroma and odontoma and therefore were ameloblastic fibro-odontomas, and one was apparently malignant (ameloblastic fibro-odontosarcoma). Excluding this last lesion, these tumors should respond well to enucleation, like their human counterparts but, to confirm this hypothesis, the margins of future examples should be carefully examined to determine that they are well-demarcated, not invasive. The microscopic features of the remaining 9 tumours could not be evaluated adequately, while another 17 tumors in cattle and water buffalo reported briefly could not be studied to any extent because of insufficient information.

  7. Cemento-ossifying fibroma-a rare case

    Directory of Open Access Journals (Sweden)

    Sarwar H

    2008-09-01

    Full Text Available The concept of ′fibro-osseous lesions′ of bone has evolved over the last several decades and now includes two major entities: fibrous dysplasia and ossifying fibroma, as well as the other less common lesions such as florid osseous dysplasia, periapical dysplasia, focal sclerosing osteomyelitis, proliferative periostitis of garrie, and ostitis deformans. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion regarding terminology and the criteria for its diagnosis. The cemento-ossifying fibroma is odontogenic in origin, whereas ossifying fibroma is of bony origin. This article reports a rare case of an 11-year-old male who came to us with the history of swelling in the maxillary anterior region causing difficulty in closing of mouth as well as in mastication.

  8. Central Cemento-Ossifying Fibroma: Primary Odontogenic or Osseous Neoplasm?

    Science.gov (United States)

    Woo, Sook-Bin

    2015-12-01

    Currently, central cemento-ossifying fibroma is classified by the World Health Organization as a primary bone-forming tumor of the jaws. However, histopathologically, it is often indistinguishable from cemento-osseous dysplasias in that it forms osteoid and cementicles (cementum droplets) in varying proportions. It is believed that pluripotent cells within the periodontal membrane can be stimulated to produce either osteoid or woven bone and cementicles when stimulated. If this is true, cemento-ossifying fibroma would be better classified as a primary odontogenic neoplasm arising from the periodontal ligament. Cemento-ossifying fibromas also do not occur in the long bones. The present report compares several entities that fall within the diagnostic realm of benign fibro-osseous lesions and reviews the evidence for reclassifying central cemento-ossifying fibroma as a primary odontogenic neoplasm. Copyright © 2015 American Association of Oral and Maxillofacial Surgeons. Published by Elsevier Inc. All rights reserved.

  9. Cemento-ossifying fibroma of the maxilla: a case report.

    Science.gov (United States)

    Verma, Piyush; Rathore, Praveen K; Mrig, Sumit; Pal, Manisha; Sial, Ankush

    2011-07-01

    We report a case of very large ossifying fibroma of the maxilla in a 22-year-old male. It is a bony tumour of the maxilla of possibly odontogenic origin with aggressive behavior and high tendency for recurrence.

  10. A case report of cemento-ossifying fibroma.

    Science.gov (United States)

    Sarwar, Hashmi G; Jindal, M K; Ahmad, Samshad

    2010-06-01

    The concept of 'fibro-osseous lesions' of bone evolved over the last several decades to include two major entities: fibrous dysplasia and ossifying fibroma as well as the other less common lesions such as florid osseous dysplasia, periapical dysplasia, focal sclerosing osteomyelitis, proliferative periostitis of garrie and ostitis deformans. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of confusion of terminology and criteria of diagnosis. The cemento-ossifying fibroma is odontogenic in origin where as ossifying fibroma of bony origin. This article reports a case of an 11-year-old male who came to us with the history of swelling at the maxillary anterior region causing difficulty in closing of mouth as well as mastication.

  11. Intraneural fibroma of the median nerve at the wrist.

    Science.gov (United States)

    Burrows, Anthony M; Folpe, Andrew L; Wenger, Doris E; Spinner, Robert J

    2014-06-01

    Distal median neuropathy from carpal tunnel syndrome is the most well known lesion affecting the median nerve. Mass lesions may affect the nerve at the wrist. We present to our knowledge the first histologically confirmed case of an intraneural fibroma.

  12. Fibroma of tendon sheath located within Kager's triangle.

    Science.gov (United States)

    Jacobs, Eva; Witlox, Marianne A; Hermus, Joris P S

    2014-01-01

    The formation of a fibroma of the tendon sheath, a rare, slow-growing, benign tumor, usually occurs in the upper extremities of young adult males. We present an extremely rare case of a fibroma of the tendon sheath arising adjacent to the Achilles tendon within Kager's triangle in a 41-year-old female. The patient presented with progressive pain localized to the posterior aspect of the left ankle. Complete excision and histopathologic analysis of the fibroma were performed. The patient experienced an uneventful recovery after the intervention and had no evidence of recurrence after 3 months of follow-up. Fibroma of the tendon sheath should be included in the differential diagnosis when a patient presents with a painful soft tissue mass in Kager's triangle.

  13. MRI features of ovarian fibromas: emphasis on their relationship to the ovary

    Energy Technology Data Exchange (ETDEWEB)

    Oh, S.N. [Department of Radiology, Kangnam St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seocho-Ku, Seoul (Korea, Republic of); Rha, S.E. [Department of Radiology, Kangnam St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seocho-Ku, Seoul (Korea, Republic of)], E-mail: serha@catholic.ac.kr; Byun, J.Y.; Lee, Y.J. [Department of Radiology, Kangnam St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seocho-Ku, Seoul (Korea, Republic of); Jung, S.E. [Department of Radiology, St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Youngdungpo-gu, Seoul (Korea, Republic of); Jung, C.K. [Department of Hospital Pathology, Kangnam St. Mary' s Hospital, College of Medicine, Catholic University of Korea, Seocho-Ku, Seoul (Korea, Republic of); Kim, M.R. [Department of Obstetrics and gynecology, Kangnam St. Mary' s Hospital, College of Medicine, The Catholic University of Korea, Seocho-Ku, Seoul (Korea, Republic of)

    2008-05-15

    Aim: To evaluate the magnetic resonance (MR) imaging features of ovarian fibromas, emphasizing the presence and shape of the ovary on the same side of the fibroma. Materials and methods: MR images from 23 patients with 24 histologically proven ovarian fibromas were reviewed by two radiologists. Eleven were pre-menopausal and 12 were postmenopausal. The presence and shape of the ovarian tissue on the same side of the fibroma were evaluated on T2-weighted MR images. Results: In 11 (46%) of the 24 ovarian fibromas, the ipsilateral ovary was detected on T2-weighted images. The ovary was crescent-shaped along the periphery of the fibroma in six (55%) of 11 fibromas and had a normal, oval shape in five (45%). Of these five tumours, the ovary was connected to the fibromas by a pedicle-like structure in three and was closely attached to the periphery of the fibromas in two. The ipsilateral ovary was detected in 10 (83%) of 12 fibromas in pre-menopausal patients, and in one (8%) of 12 fibromas in postmenopausal patients. There was a statistically significant difference (p = 0.001) in the presence of detectable ipsilateral ovary between pre-menopausal and postmenopausal women. Conclusions: Detection of the remaining ovary on the same side as the fibroma is not unusual on MRI, especially in pre-menopausal women, and the shape of the ovary may be normal in cases of fibromas with exophytic growth from the periphery of the ovary.

  14. Chondromyxoid fibroma of the frontal bone in a teenager

    Energy Technology Data Exchange (ETDEWEB)

    Kadom, Nadja [Children' s National Medical Center, Department of Radiology, Division of Neuroradiology, Washington, DC (United States); Rushing, Elisabeth J. [Armed Forces Institute of Pathology, Washington, DC (United States); Yaun, Amanda [Children' s National Medical Center, Division of Neurosurgery, Washington, DC (United States); Santi, Mariarita [Children' s National Medical Center, Division of Neuropathology, Washington, DC (United States)

    2009-01-15

    We report a skull chondromyxoid fibroma with symptomatic intracranial extension causing initial misdiagnosis as a psychiatric disorder in a 14-year-old child. CT performed for work-up of the patient's ''stuffy nose'' revealed a large calcified frontal bone mass with extensive intracranial growth. We present this child with the diagnosis of intracranial chondromyxoid fibroma with detailed neuroimaging and neuropathology correlations. (orig.)

  15. Desmoplastic fibroma of the mandible in an infant

    Energy Technology Data Exchange (ETDEWEB)

    Wippold, Franz J. [Washington University Medical Center, Neuroradiology Section, Mallinckrodt Institute of Radiology, St. Louis, MO (United States); Uniformed Services University of the Health Sciences, Bethesda, MD (United States); White, Frances V. [Louis Children' s Hospital, Washington University School of Medicine, Department of Pathology, Barnes-Jewish Hospital and St., St. Louis, MO (United States); Jamroz, Gregory [Washington University Medical Center, Neuroradiology Section, Mallinckrodt Institute of Radiology, St. Louis, MO (United States); Haughey, Bruce; Forsen, James [Barnes-Jewish Hospital and St. Louis Children' s Hospital, Washington University School of Medicine, Department of Otolaryngology Head and Neck Surgery, St. Louis, MO (United States)

    2005-09-01

    We report the CT and MR imaging findings of a case of a desmoplastic fibroma of the mandible in a 6-month-old girl who presented with a rapidly enlarging facial mass and who represents one of the youngest reported children with this rare tumor. Although imaging is non-specific and these lesions are best distinguished histologically, the desmoplastic fibroma should be considered when there is an occurrence of any bubbly or cystic expansile mandibular lesion presenting in childhood. (orig.)

  16. A chondromyxoid fibroma of the fibula: a case report

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Ji Yeoun; Kim, Hong Soo; Lim, Hyung Guhn; Kim, Soo Jung; Joo Myung Jin [Presbyterian Medical Center, Chounju (Korea, Republic of)

    2000-07-01

    Chondromyxoid fibroma is the least common benign bone tumor, accounting for less than 1% of all bone tumors. Pathologically, it is composed of varying proportions of chondroid, myxoid and fibrous elements. The most common anatomical site is the metaphyseal region of the long bone, and the typical radiologic appearance is a cortical expansile osteolytic lesion with a lobulated sclerotic margin, and septa. We report the plain and MRI findings of a relatively typical chondromyxoid fibroma occurring in the proximal fibula. (author)

  17. Peripheral Ameloblastic Fibroma: Report of a Rare Case

    Science.gov (United States)

    Kalantari, Mahsa; Samieirad, Sahand; Kalantari, Parisa

    2016-01-01

    Ameloblastic fibroma is a rare mixed odontogenic tumor mostly occurring in the posterior region of the mandible. The peripheral variant is very rare and to the best of our knowledge, only three cases have been reported in the English literature. In this report, we describe a case of peripheral ameloblastic fibroma in a 54-year-old woman with two years of follow-up. PMID:27942554

  18. MR imaging of calcifying aponeurotic fibroma of the thigh

    Energy Technology Data Exchange (ETDEWEB)

    Kwak Hyo-Sung [Dept. of Diagnostic Radiology, Univ. MedicalSchool, Chonbuk (Korea); Department of Diagnostic Radiology, The Armed Forces Kyae Ryong Dae District Hospital, Post Office Box No. 37, Bunam-ri, Dooma-myun, Nonsan-city, Chungnam, 320-919 South Korea (Korea); Lee Sang-Yong [Dept. of Diagnostic Radiology, Univ. MedicalSchool, Chonbuk (Korea); Kim Jung-Ryul; Lee Kwang-Bok [Department of Orthopedic Surgery, Chonbuk National University Medical School, South Korea, Chonbuk (Korea)

    2004-05-01

    Calcifying aponeurotic fibroma is a rare, benign soft-tissue proliferation that occurs in the distal extremities in children. Because this lesion has a tendency to recur after surgical resection, MR imaging to determine the extent of the tumor for surgical planning is optimal. We report the MR findings in a 4-year-old boy with a calcifying aponeurotic fibroma of the thigh. (orig.)

  19. Peripheral Ameloblastic Fibroma: Report of a Rare Case.

    Science.gov (United States)

    Kalantari, Mahsa; Samieirad, Sahand; Kalantari, Parisa

    2016-12-01

    Ameloblastic fibroma is a rare mixed odontogenic tumor mostly occurring in the posterior region of the mandible. The peripheral variant is very rare and to the best of our knowledge, only three cases have been reported in the English literature. In this report, we describe a case of peripheral ameloblastic fibroma in a 54-year-old woman with two years of follow-up.

  20. Congenital ameloblastic fibroma in association with oculoauriculovertebral spectrum.

    Science.gov (United States)

    Naidoo, L C; Stephen, L X

    1998-05-15

    Although orodental anomalies have been reported to occur in patients with oculoauriculovertebral spectrum, no previous publications in the English literature have been located that describe an ameloblastic fibroma in a patient with this condition. This report presents a 15-month-old female monozygotic twin with concomitant oculoauriculovertebral spectrum and a congenital ameloblastic fibroma of the mandible. A theory linking the pathogenesis of the two conditions is also raised.

  1. Oral fibroma with HPV-associated epithelial dysplasia: even in fibromas you should look for the unexpected.

    Science.gov (United States)

    Argyris, Prokopios P; Koutlas, Ioannis G

    2014-05-01

    Fibromas are the most common soft tissue lesions of the oral cavity and are generally attributed to trauma. Koilocytic dysplasia refers to human papillomavirus (HPV)-related epithelial cytopathic effect. Koilocytic dysplasia is considered neoplastic. Herein, we report a case of oral fibroma with HPV-induced dysplastic changes of the surface epithelium confirmed by immunohistochemical stains for p16 and p53 as well as HPV in situ hybridization.

  2. Giant Cell Fibroma in Children: Report of Two Cases and Literature Review

    Directory of Open Access Journals (Sweden)

    Nikolaos G. Nikitakis

    2013-02-01

    Full Text Available Background: Giant cell fibroma is a type of fibrous tumour of the oral mucosa which rarely affects children under the age of 10. The purpose of this paper was to contribute two clinically and histologically documented cases of giant cell fibroma in the free gingiva of a 7 and 6 year old boys. Methods: Both nodules were presented in the mandibular anterior region. In the differential diagnosis several fibrous hyperplastic lesions were considered such as traumatic fibroma, papilloma, peripheral ossifying fibroma, peripheral odontogenic fibroma, giant cell fibroma and odontogenic hamartoma. Results: The lesions were removed and the histological examination revealed fibrocollagenous connective tissue with the presence of stellate giant cells which confirmed the diagnosis of giant cell fibroma. Conclusions: Dentists should be aware of the existence of giant cell fibroma in children, which must be included in the differential diagnosis of nodular lesions of the gingiva and adequately diagnosed and treated by removal and histopathological examination.

  3. Chondroblastoma and chondromyxoid fibroma : disentangling the neoplastic chondrogenesis of two rare cartilaginous tumours

    NARCIS (Netherlands)

    Romeo, Salvatore

    2010-01-01

    The scope of this study was to disentangle neoplastic chondrogenesis in two rare cartilaginous tumours: chondroblastoma and chondromyxoid fibroma. It was addressed: 1 The spectrum of phenotypic differentiation in chondroblastoma and chondromyxoid fibroma, 2 The signalling pathways driving chondrobla

  4. Infantile Digital Fibroma: A Rare Fibromatosis.

    Science.gov (United States)

    Marks, Etan; Ewart, Michelle

    2016-10-01

    Infantile digital fibroma is a rare benign lesion that usually occurs during the first 2 years of life. It can be multiple, but it is usually a single lesion. If it grows large enough it can cause joint deformities or interfere with everyday activities. Microscopically, the neoplastic cells usually have inclusion bodies that are best highlighted with a Masson trichrome stain but can often be seen on hematoxylin-eosin staining. Treatment for this entity is usually watchful waiting because of its ability to spontaneously regress, but excision is recommended if the lesion is symptomatic. More recently, fluorouracil or injectable steroids have shown great promise in inducing regression without the complications that accompany surgery.

  5. Juxtacortical chondromyxoid fibroma arising in an apophysis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Seong Ho; Kong, Keun Young; Chung, Hye Won; Kang, Heung Sik [Dept. of Radiology, Seoul National University College of Medicine (Korea); Kim, Chong Jai [Dept. of Pathology, Seoul National University College of Medicine, Seoul (Korea); Lee, Sang Hoon [Dept. of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul (Korea)

    2000-08-01

    We present a rare case of juxtacortical chondromyxoid fibroma arising in the lesser trochanter of the right femur which corresponds to an apophysis. Radiography showed a well-defined expansive lesion with a sclerotic margin measuring 5 x 3.5 cm in diameter in the lesser trochanter. On spin echo T1-weighted images, the lesion revealed low signal intensity similar to muscle. On spin echo T2-weighted images, the lesion revealed high heterogeneous signal intensity, which after gadolinium injection showed heterogeneous enhancement. The inner margin of the cortex was intact and adjacent bone marrow was of normal signal intensity. The outer margin of the lesion was also clearly defined and extension into adjacent soft tissue beyond the exophytic cortical outgrowth was not evident. (orig.)

  6. [Non-ossifying fibroma (metaphyseal fibrous defect)].

    Science.gov (United States)

    Rogozhin, D V; Konovalov, D M; Kozlov, A S; Talalaev, A G; Ektova, A P

    2016-01-01

    Non-ossifying fibroma (NOF) or metaphyseal fibrous defect (MFD) is benign fibroblast proliferation with the presence of osteoclast-like multinucleated giant cells. The most cases of NOF/MFD occur in the metaphysis of the long tubular bones of the lower extremities, more commonly in the metaphysis of the femur and in the proximal metaphysis of the tibia. This lesion has a characteristic X-ray pattern and requires no surgical intervention, except for cases of a pathologic fracture or a risk for the latter. The paper analyzes 35 NOF/MFD cases in children and adolescents. It has been found that one and all patients have undergone surgery, suggesting the low awareness of this abnormality among radiodiagnosticians, pathologists, and surgeons.

  7. Ovarian fibroma--clinical and histopathological characteristics.

    Science.gov (United States)

    Sivanesaratnam, V; Dutta, R; Jayalakshmi, P

    1990-11-01

    Twenty-three cases of ovarian fibroma, comprising 3% of all benign tumors seen over a 20-year period, were analyzed. It was unilateral in all cases affecting more commonly the left ovary (70%). Whilst a majority of cases (77%) were encountered in the reproductive age group, the tumor was rare before the second decade. Only in 13% of cases was ascitis clinically detectable. This was not influenced by the size and weight (average of 9.3 x 10.8 x 11.1 cm and 959 g, respectively) of the tumors; a smooth-surfaced tumor was, however, associated with a greater amount of peritoneal fluid. Varying degrees of calcification in some tumors are detectable on ultrasonography and occasionally on abdominal radiography. The classical Meig's Syndrome was seldom encountered. The histopathological features, diagnostic problems and management are discussed.

  8. Peripheral cementifying fibroma: a clinical diagnostic dilemma.

    Science.gov (United States)

    Choubey, Shikha; Banda, Naveen Reddy; Banda, Vanaja Reddy; Vyawahare, Saket

    2013-05-13

    The peripheral ossifying fibroma (POF) is a reactive gingival overgrowth occurring frequently in the anterior maxilla. It originates in the cells of the periodontal ligament and is more common in children and young adults. In the current article a case of gingival over growth, which was thought to be puberty-induced gingivitis was seen in the lower anterior maxillary gingiva. Histology of the excised tissue showed cellular, fibrous connective tissue stroma with calcified osseous calcifications indicative of POF. The definitive diagnosis is established only by histological examination, which revealed the presence of highly cellular connective tissue with focal calcifications. Surgery is the treatment of choice, though the recurrence rate can reach 20% in case of POF. After histological confirmation the recall and clinical evaluation protocol of POF varies due to its increased recurrence rate, which the general dentist should be aware of.

  9. Chondromyxoid fibroma invasion of the transverse-sigmoid sinus junction causing posterior fossa hemorrhage.

    Science.gov (United States)

    Hersh, David S; Firempong, Alexander O; Chesler, David; Castellani, Rudolph J; Woodworth, Graeme F

    2016-02-01

    We report a 50-year-old woman with a chondromyxoid fibroma of the occipital bone, who presented with a cerebellar hemorrhage due to invasion of the adjacent sinus. Chondromyxoid fibromas are benign cartilaginous tumors. However, this case represents the first example, to our knowledge, of a chondromyxoid fibroma invading the transverse-sigmoid junction, resulting in intracranial hemorrhage. Our report highlights that the location of an intracranial chondromyxoid fibroma is an important factor in guiding surgical management.

  10. CT and MR findings of ovarian fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Soo Jin; Rho, Myung Ho; Kim, Byung Heon; Song, Yun Gyu; Lee, Soo Han; Choi, Pil Yeob; Sung, Young Soon; Kwon, Jae Soo; Lee, Sang Wook [Masan Samsung Hospital, Masan (Korea, Republic of)

    1997-08-01

    To evaluate the charateristic CT and MR findings of the primary ovarian fibromas. We retrospectively reviewed 11 cases which had undergone precontrast and postcontrast scanning, and two in which cases T1-weighted (WI) and postcontrast T1WI and T2WI images had been done. All cases were pathologically confirmed after surgical resection. These masses were analysed on the bases of clinical symptoms, age, size(longest diameter), laterality, margin, attenuation(unenhanced and enhanced), signal intensity(SI), calcification, and amount of the ascites. The patients' mean age was 46.6(range, 22-81)years, and the longest diameter was 14.8(range, 8-28)cm. All tumors were unilateral, and eight were located in the left ovary and five in the right ovary. In all cases, the tumor margin was well-defined;seven were lobulated, four were oval, one was round, and one was nodularly marginated. On CT scan, the masses showed mild to moderate heterogenous enhancement with irregular lower density portions. The amount of the ascites was marked in three cases(23%), mild in two(15%), and minimal in three cases. Calcification were seen in 3 of 11 CT cases(27%), and in one, this was extensive. On MR scans, signal intensity (SI) of the masses on T1WI was isoSI, relativetive to the uterine myometrium, and heterogeneously enhanced after infusion of contrast media. On T2WI, SI was slightly lower that of the uterine myometrium with internal high SI portions. The characteristic finding of ovarian fibroma is a unilateral, well-defined, oval or lobulated, solid mass with or without ascites and calcification. On CT scan, tumor has mild to moderate heterogeneous enhancement. On MR scan, SI of mass is isoSI on T1WI with heterogeneous enhancement, and low SI on T2WI due to fibrous component.

  11. Fibroma of tendon sheath with 11q rearrangements.

    Science.gov (United States)

    Nishio, Jun; Iwasaki, Hiroshi; Nagatomo, Masaya; Naito, Masatoshi

    2014-09-01

    Fibroma of tendon sheath is an uncommon, benign fibroblastic tumor that usually occurs in the upper extremities of young and middle-aged adults. A clonal chromosomal aberration, t(2;11)(q31-32;q12), has been described in one case. We herein present a unique cytogenetic finding of fibroma of tendon sheath arising in the first web space of the right hand of a 38-year-old woman. Physical examination showed a 3.5-cm, firm, mobile, non-tender mass. Magnetic resonance imaging showed a well-defined soft tissue mass with iso- to slightly-low signal intensity relative to skeletal muscle on both T1- and T2-weighted sequences. Contrast-enhanced T1-weighted sequences demonstrated moderate patchy enhancement of the mass. A fibroma or giant cell tumor of tendon sheath was suggested, and the lesion was marginally excised. Histological examination confirmed the diagnosis of fibroma of tendon sheath. Cytogenetic analysis revealed a novel t(9;11)(p24;q13-14) translocation among other karyotypic abnormalities. The postoperative course was uneventful, and the patient is doing well without local recurrence two months after surgery. To the best of our knowledge, this is only the second report of fibroma of tendon sheath with clonal chromosomal abnormalities.

  12. Resection of left ventricular fibroma with subacute papillary muscle rupture.

    Science.gov (United States)

    Leja, Monika J; Perryman, Lynda; Reardon, Michael J

    2011-01-01

    Cardiac fibroma is a rare, benign tumor that occurs chiefly in children and rarely in adults. Most fibromas occur in the ventricles and may reach a very large size that complicates surgical removal. Herein, we report the case of a 38-year-old woman who presented with shortness of breath, fatigue, and lightheadedness and was found to have a 6 × 8-cm fibroma of the left ventricle. Surgical resection was successful, but 7 days later she developed sudden-onset severe mitral regurgitation due to partial disruption of the posterolateral papillary muscle. Mitral valve replacement with a 27-mm mechanical valve was performed. Five years later, the patient remained well, without evident tumor recurrence or cardiac dysfunction.Mitral valve dysfunction with regurgitation has been reported to occur before, immediately after, and late after the resection of left ventricular fibromas. To our knowledge, this is the 1st report of subacute papillary muscle rupture after the resection of a left ventricular fibroma. This case highlights the need to evaluate mitral valve function by carefully inspecting the resection margins after surgery and interpreting the echocardiographic results during the acute, subacute, and late time frames.

  13. A case report of cemento-ossifying fibroma presenting as a mass of the ethmoid sinus.

    Science.gov (United States)

    Hekmatnia, Ali; Ghazavi, Amirhossein; Saboori, Masih; Mahzouni, Parvin; Tayari, Nazila; Hekmatnia, Farzaneh

    2011-02-01

    Cemento-ossifying fibroma is a lesion containing both fibrous and osseous components. Such lesions include fibrous dysplasia, ossifying fibroma, cemento-ossifying fibroma and cementifying fibroma. Periodontal membrane is the origin of fibro-osseous lesions other than fibrous dysplasia.Here a clinical case of a young woman referred for evaluation of a mass in the right side of face between eye and nose is presented. The first time she noticed the mass was 2 years ago and was growing larger inwards. She was treated with surgical resection.In this case of a cemento-ossifying fibroma, histological interpretation was critical, and was the basis of correct treatment.

  14. [Desmoplastic fibroma of the rib: two case reports].

    Science.gov (United States)

    Ayadi-Kaddour, Aïda; Ben Slama, Sana; Braham, Emna; Abid, Leila; Ismail, Olfa; Smati, Belhassen; Djilani, Habiba; El Mezni, Faouzi

    2005-10-01

    Desmoplastic fibroma is a very rare primary tumor of bone, closely related to aggressive fibromatosis of soft tissue. Although considered a benign lesion, it can be very aggressive locally and has a high rate of local recurrence after incomplete surgical excision. Radiologically, the lesion shows no distinctive features, often simulating osteosarcoma, fibrous dysplasia, or fibrosarcoma. Rib involvement by desmoplastic fibroma is extremely rare. We present two cases of desmoplastic fibroma involving this unusual location with lytic costal lesion and chest wall extension. Histological examination after surgical resection revealed that the tumor consisted of spindle cells with small, elongated nuclei in a background of numerous collagen fibers and infiltrating lamellar bone. There was no evidence of nuclear atypia, mitotic activity, or necrosis. We also discuss histological differential diagnosis as well as clinical features and the radiological and pathologic findings of this rare disease. Recognition of this entity is important to ensure proper surgical treatment.

  15. Ossifying fibroma in a miniature rex rabbit (Oryctolagus cuniculus).

    Science.gov (United States)

    Whitten, K A; Popielarczyk, M M; Belote, D A; McLeod, G C; Mense, M G

    2006-01-01

    In humans and animals, ossifying fibroma is a benign neoplasm that most frequently affects the mandible, often resulting in cosmetic deformities and malocclusion. It is considered rare in animals and most frequently affects young horses. A surgical biopsy of a solitary mass located beneath the gingiva in the right maxillary region, which had overgrown teeth and expanded the adjacent hard palate from a 6-year-old miniature Rex rabbit was submitted for light microscopic examination. The submitted incisional biopsy specimen was pale pink, firm, and nodular. Histopathologically, the neoplasm was composed of fibroblastic cells separated by abundant collagen. The neoplastic cells were interwoven with osteoblasts surrounding islands of mineralized, bony matrix containing few, widely spaced, often empty, lacunae. Minimal inflammation was present. Based on the histopathologic features, the tumor was diagnosed as an ossifying fibroma. To our knowledge, this is the first report of an ossifying fibroma in a rabbit.

  16. Large twisted ovarian fibroma in menopausal women: a case report.

    Science.gov (United States)

    Boujoual, Majdouline; Hakimi, Ihsan; Kouach, Jaouad; Oukabli, Mohamed; Moussaoui, Driss Rahali; Dehayni, Mohammed

    2015-01-01

    Ovarian fibroma is the most common benign solid tumors of the ovary, commonly misdiagnosed as uterine fibromaor as malignant ovarian tumors. It occurs generally in older perimenopausal and postmenopausal women. Occasionally large fibromas may undergo torsion causing acute abdominal pain. Doppler Ultrasonographyimaging is the choice study. CT and MRI are often needed for further characterization and differentiation from other solid ovarian masses. The choice treatment is surgical removal with intraoperative frozensection. Immunohistochemicalanalysis is recommended to rule out the differential diagnosis. Here we present a case of a postmenopausal woman with a large twisted ovarian fibroma reflecting diagnostic and management difficulties including potential misdiagnosis of the tumor as a malignant ovarian neoplasm that may influence the surgical approach.

  17. Ghost cell differentiation and calcification in ameloblastic fibroma.

    Science.gov (United States)

    Luo, Hai Yan; Gao, Yan

    2013-01-01

    Ghost cell differentiation within an ameloblastic fibroma is extremely rare. The ghost cells found in an ameloblastic fibroma in previously reported cases were all associated with a typical calcifying odontogenic cyst. Here, we report a case of an ameloblastic fibroma with focal ghost cells and calcifications in some neoplastic epithelial islands, but without other histologic manifestations consistent with a calcifying odontogenic cyst. The patient was a 13-year-old Chinese boy who presented with a bony-hard swelling in the posterior mandibular region over a 6-month period. Radiographs showed a well-defined multilocular radiolucency associated with an unerupted tooth. The lesion was mostly cystic-solid and comprised of odontogenic epithelial strands, islands and myxoid ectomesenchymal component microscopically. Small groups of ghost cells and calcification were noted in the epithelial islands.

  18. Hybrid odontogenic tumor of calcifying odontogenic cyst and ameloblastic fibroma.

    Science.gov (United States)

    Yoon, Jung Hoon; Kim, Hyung Jun; Yook, Jong In; Cha, In Ho; Ellis, Gary L; Kim, Jin

    2004-07-01

    Odontogenic tumors composed of 2 distinct types of lesions are unusual. We report an odontogenic tumor that was composed of calcifying odontogenic cyst and ameloblastic fibroma that occurred in the right posterior maxilla of a 22-year-old Korean woman. The tumor had a cystic component with an ameloblastic epithelial lining and conglomerates of so-called ghost cells, and there were deposits of dentinoid material adjacent to the cyst. These are features characteristic of calcifying odontogenic cyst. Enamel organ-like epithelial islands were observed within a dental papilla-like stroma of the cyst wall. Additionally, a solid portion of the tumor had characteristic features of ameloblastic fibroma, i.e., a myxoid cellular stroma with numerous elongated islands of ameloblastic epithelium. Ghost cell masses were found in the area of ameloblastic fibroma as well. The distribution of the ghost cells suggests that this is a hybrid lesion rather than a collision tumor.

  19. Spontaneous ameloblastic fibroma in a young Guinea pig.

    Science.gov (United States)

    Tanaka, Makoto; Sawamoto, Osamu

    2013-09-01

    A spontaneous ameloblastic fibroma was found in a 9-week-old guinea pig. Histopathologically, neoplastic cells consisted of two components: an odontogenic epithelium and odontogenic mesenchyme. The odontogenic epithelium formed strands, nests and islands that were interspersed within the odontogenic mesenchyme. In the marginal region, odontoblasts and scant dysplastic eosinophilic material were seen between these two components. Immunohistochemically, the odontogenic epithelium was positive for cytokeratin AE1/AE3, and the odontogenic mesenchyme and odontoblast were positive for vimentin, in the same manner as in the normal tooth germ (control). We could not obtain conclusive data suggesting that the eosinophilic material was dental hard tissue because the eosinophilic material was not stained specifically by any methods. Based on these histological characteristics, the tumor in the present case was diagnosed as an ameloblastic fibroma. This is the first report of ameloblastic fibroma in guinea pigs.

  20. Fibroma de Vulva (Molluscum Pendulum: Relato de Caso Vulvar Fibroma: Case Report

    Directory of Open Access Journals (Sweden)

    Alfredo Roberto Netto

    2001-04-01

    Full Text Available É apresentado um caso de fibroma de vulva, modalidade molluscum pendulum, em uma jovem de 20 anos. O tumor desenvolveu-se após a menarca com evolução lenta e progressiva. Ao exame físico, observou-se volumosa massa pediculada, indolor, com inserção no terço superior do grande lábio esquerdo, de consistência elástica, com diâmetro maior em sua parte distal de 12 cm por 23 cm de comprimento. Como tratamento, optou-se pela exérese pela base do pedículo, sob anestesia local. O tumor apresentou o peso de 950 g. Complementa-se com revisão de literatura.A vulvar fibroma, of the molluscum pendulum type, was present in a 20-year-old patient. The tumor began to develop slowly after her menarche, when she was 14 years of age. The physical examination revealed a mass with considerable volume, painless, located at the upper third of the greator left lip, elastic consistency, greater diameter at its distal portion measuring 12 cm by 23 cm in length. The treatment was exeresis from the base of the pedicle, under local anesthesia. The tumor weighed 950 g. A literature review is included.

  1. Chondromyxoid fibroma in the sella turcica region.

    Science.gov (United States)

    Xu, Hongzhi; Qin, Zhiyong; Shi, Zhenhua

    2011-10-01

    Chondromyxoid fibroma (CMF) is an uncommon tumor that primarily develops in the long bones of young males. It is rarely seen in the skull and involvement of the skull base is rare. We report a patient with CMF arising in the region of the sella turcica. A literature review regarding the clinical and histological features of CMF, as well as recommended modalities of treatment, is presented. A 55-year-old male was admitted with polyuria and headache. A CT scan showed a well-defined expansive lesion with a sclerotic margin measuring approximately 2 cm in diameter in the sellar region. T1-weighted MRI revealed a well-circumscribed, lobulated and strongly enhancing lesion. On the T2-weighted MRI, the lesion showed high heterogeneous signal intensity. Using the trans sphenoidal approach, surgical exploration revealed a well-defined tumor underneath the optic chiasm. The piecemeal tumor removal was considered complete. We conclude that sellar region CMF can cause severe disabilities due to tumor compression. CMF should be taken into consideration in the differential diagnosis of a solitary tumor mass in the sellar area. As much as possible, surgical resection of the tumor is the cornerstone of treatment. Although CMF are generally regarded as benign neoplasms, they may show an infiltrative pattern and may recur; particularly when they are in locations where complete surgical excision may be difficult or impossible.

  2. Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma.

    Science.gov (United States)

    Nair, Sreelakshmi N; Kini, Raghavendra; Rao, Prasanna Kumar; Bhandarkar, Gowri P; Kashyp, Roopashri Rajesh; Rai, Manjunath; Naik, Neel; Santhosh, Athul

    2016-01-01

    Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. The most commonly affected facial bone is the maxilla, with facial asymmetry being the chief complaint. The lesion in many instances is confused with ossifying fibroma (OF). Diagnosis of these two lesions has to be done based on clinical, radiographic, and microscopic findings. Here, we present a case of fibrous dysplasia of maxilla in a nine-year-old boy mimicking juvenile ossifying fibroma.

  3. Giant cemento-ossifying fibroma of the mandible.

    Science.gov (United States)

    Naik, Raghavendra Mahadev; Guruprasad, Yadavalli; Sujatha, D; Gurudath, Shubha; Pai, Anuradha; Suresh, Kv

    2014-01-01

    Cemento-ossifying fibroma (COF) is classified as a fibro-osseous neoplasm and included among the non-odontogenic tumors derived from the mesenchymal blast cells of the periodontal ligament, with a potential for forming fibrous tissue, cementum and bone, or a combination of such elements. These are slow-growing lesions, and are more frequent in women between the third and fourth decades of life. Case reports of massive expansile COF, measuring more than 10 cm are rarely reported in the literature. We report a case of giant cemento-ossifying fibroma of the mandible in a 34 year old female patient.

  4. Cemento-ossifying fibroma of the mandible. A clinicopathological report.

    Science.gov (United States)

    Bala, Tapas K; Soni, Sarmeshta; Dayal, Prakriti; Ghosh, Indrajeet

    2017-05-01

    Cemento-ossifying fibromas are rare fibro-osseous benign neoplasms that affect the jaws. They are included in the group of mesodermal odontogenic tumors and commonly present as a progressively growing lesion that might attain enormous size with resultant deformity, if left untreated. A confusion prevails on the terminology, which can only be confirmed by histopathologic evaluation. A case of cemento-ossifying fibroma involving the right mandible is described in a 30 year-old female patient. The clinical, radiographic, histologic features are presented and the various differential diagnosis are discussed.

  5. Giant cardiac fibroma: an unusual cause of failure to thrive.

    Science.gov (United States)

    Navarini, Susanne; Latzin, Philipp; Kadner, Alexander; Carrel, Thierry; Hutter, Damian

    2013-06-01

    Cardiac fibromas are extremely rare in the general pediatric population and may present with a wide spectrum of clinical signs, including life-threatening arrhythmias and sudden death. We report a 14-month-old boy who presented with failure to thrive as the only symptom. Echocardiography showed a large cardiac fibroma in the right ventricle. Cardiac magnetic resonance imaging confirmed the diagnosis. After complete surgical tumor resection, the boy showed normal catch-up growth. This case underlines the diversity of clinical features of cardiac tumors, which implies that they should be considered early in the differential diagnosis of infants with failure to thrive.

  6. Juvenile Trabecular Ossifying Fibroma of the Maxilla: a Case Report

    Science.gov (United States)

    Aboujaoude, Samia; Aoun, Georges

    2016-01-01

    Introduction: Juvenile ossifying fibromas are uncommon benign tumors. Their aggressiveness added to their high tendency to recur, provoke real diagnostic and therapeutic challenges for the dental practitioner and make a postoperative follow-up over the years indispensable. Case report: In this report, we present a case of a seven-year-old girl presented with a swelling in the face at the upper right maxillary region. After clinical, radiological, and histopathological examinations the diagnosis of trabecular juvenile ossifying fibroma was made. The lesion was surgically excised and followed up for two years with no evidence of recurrence. PMID:28210024

  7. Rare case of dual lesion: nonossifying fibroma and osteochondroma.

    Science.gov (United States)

    Grimshaw, Charles S; Zawin, Joan; Brink, David S; Greenberg, David D

    2014-05-01

    In this paper, we offer radiographic and pathologic evidence of a unique coexisting dual lesion. A 14-year-old boy presented for evaluation of a painful right knee after sustaining a twisting injury. The patient was found to have a torn anterior cruciate ligament, in addition to incidental finding of distal femoral dual lesion composed of tissue consistent with a nonossifying fibroma and an osteochondroma. To our knowledge, this is the first report in the medical literature of a dual lesion containing both an osteochondroma and nonossifying fibroma.

  8. Cutaneous fibroma in a captive common snapping turtle (Chelydra serpentina).

    Science.gov (United States)

    Gonzales-Viera, O; Bauer, G; Bauer, A; Aguiar, L S; Brito, L T; Catão-Dias, J L

    2012-11-01

    An adult female common snapping turtle (Chelydra serpentina) had a mass on the plantar surface of the right forelimb that was removed surgically. Microscopical examination revealed many spindle cells with mild anisocytosis and anisokaryosis and a surrounding collagenous stroma. There were no mitoses. Immunohistochemistry showed that the spindle cells expressed vimentin, but not desmin. A diagnosis of cutaneous fibroma was made. Tumours are reported uncommonly in chelonian species. Cutaneous fibroma has been diagnosed in an alligator snapping turtle (Macrochelys temminckii), but not previously in a common snapping turtle.

  9. Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma

    Science.gov (United States)

    Rao, Prasanna Kumar; Bhandarkar, Gowri P.; Rai, Manjunath; Naik, Neel; Santhosh, Athul

    2016-01-01

    Fibrous dysplasia (FD) is a condition characterized by excessive proliferation of bone forming mesenchymal cells which can affect one bone (monostotic type) or multiple bones (polyostotic type). It is predominantly noticed in adolescents and young adults. Fibrous dysplasia affecting the jaws is an uncommon condition. The most commonly affected facial bone is the maxilla, with facial asymmetry being the chief complaint. The lesion in many instances is confused with ossifying fibroma (OF). Diagnosis of these two lesions has to be done based on clinical, radiographic, and microscopic findings. Here, we present a case of fibrous dysplasia of maxilla in a nine-year-old boy mimicking juvenile ossifying fibroma. PMID:28101383

  10. Cutaneous Ossifying Fibroma in a Neon Tetra (Paracheirodon innesi).

    Science.gov (United States)

    Murphy, B; Imai, D M

    2016-01-01

    A cutaneous proliferative mass was identified arising from the caudal peduncle of a captive neon tetra fish (Paracheirodon innesi). The lesion was histologically consistent with an ossifying fibroma (OF), a fibro-osseous proliferative lesion typically identified in the jaws or tooth-associated supportive tissues of mammals. Although it has been previously reported, there is no recent report of this lesion occurring in a fish. This is the first report of a cutaneous ossifying fibroma in a characin fish. The authors speculate on the pathogenesis of this lesion, which may have arisen from the scale-associated mesenchymal tissues.

  11. Fibroma cardíaco mimetizando cardiomiopatia hipertrófica Cardiac fibroma mimicking hypertrophic cardiomyopathy

    Directory of Open Access Journals (Sweden)

    Luís Alberto Dallan

    1989-12-01

    Full Text Available É relatado o caso de paciente com queixa de dor precordial, dispnéia e arritmia desde a adolescência, tratada clinicamente por mais de 10 anos. Nesse período, foi submetida a inúmeros exames ângio e ecocardiográficos, com suspeita inicial de endomiocardiofibrose e, posteriormente, de cardiomiopatia hipertrófica de ventrículo esquerdo. Como houve piora progressiva da sintomatologia e ausência de resposta à medicação, foi encaminhada ao nosso Serviço, onde se diagnosticou fibroma de ventrículo esquerdo. Foi submetida, com sucesso, à ressecção cirúrgica do tumor, sendo realizada reconstrução geométrica do ventrículo esquerdo. Apresenta boa evolução, decorridos dois anos, com remissão completa dos sintomas. Destacamos a dificuldade no diagnóstico diferencial desses tumores benignos e de crescimento lento, com as cardiomiopatias hipertróficas do ventrículo esquerdo.A 33 year-old woman was seen, for the first time, ten years ago, for evaluation of a recurrent chest pain, dyspnea and arrhythmia. She was submitted to echocardiographic studies and a cardiac catheterization. The diagnoses was endomyocardial fibrosis at first, and hypertrophic cardiomyopathy after. Despite treatment with propranolol and quinidine, the episodes of dyspnea and tachyarrhythmias became more frequent and severe, and the patient was guided to our Service. Cardiac re-catheterization, echocardiographic and computed tomography studies identified in traumural cardiac fibroma and the patient was referred for surgical treatment. The cardiac fibroma was successfully resected on extracorporeal bypass and with cardioplegic arrest of the heart. Repair of the heart was accomplished with a patch placed to close the left ventricular cavity. The postoperative course was uncomplicated, and she remains assymptomatic two years later. We have emphazied tha this tumor often produces clinically obscure disease, simulating particularly the left ventricle hypertrophic

  12. Desmoid-type fibromatosis-associated Gardner fibromas: prevalence and impact on local recurrence.

    Science.gov (United States)

    Cates, Justin M M; Stricker, Thomas P; Sturgeon, Duveen; Coffin, Cheryl M

    2014-10-28

    Although Gardner fibroma is a precursor lesion of desmoid tumor, the prevalence and prognostic importance of Gardner fibroma associated with desmoid tumors has not been systematically studied in adults. From 129 patients with desmoid-type fibromatosis, 170 specimens were re-examined for the presence of an associated Gardner fibroma. Clinicopathologic features of Gardner fibroma-associated desmoid-type fibromatosis were compared to desmoid tumors without associated Gardner fibroma. Recurrence-free survival was compared using multivariate Cox proportional hazard regression to account for known confounding factors. Of 104 evaluable primary desmoid tumor resections, 25 (24%) had an associated Gardner fibroma. When previous incisional biopsies and resection specimens of locally recurrent desmoid tumors were also examined, the overall prevalence of associated Gardner fibroma was 37%. Desmoid tumors arising in high risk anatomic sites (extremities or deep soft tissues of the back and chest wall) were more often associated with Gardner fibroma than tumors at other sites. Median recurrence-free survival for patients with Gardner fibroma-associated desmoid-type fibromatosis was 3.2 years, whereas median survival for patients without associated Gardner fibroma was >25 years (hazard ratio 2.8; P = 0.001). Although the presence of Gardner fibroma had no impact on the recurrence rate of desmoid tumors arising at high risk anatomic sites, associated Gardner fibroma increased the risk of recurrence 4-fold for desmoid tumors at low risk anatomic sites. Associated Gardner fibroma is under-recognized in desmoid-type fibromatosis and increases the risk of local recurrence for a subgroup of patients. Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

  13. Identification of previously unrecognized FAP in children with Gardner fibroma.

    Science.gov (United States)

    Vieira, Joana; Pinto, Carla; Afonso, Mariana; do Bom Sucesso, Maria; Lopes, Paula; Pinheiro, Manuela; Veiga, Isabel; Henrique, Rui; Teixeira, Manuel R

    2015-05-01

    Fibromatous soft tissue lesions, namely desmoid-type fibromatosis and Gardner fibroma, may occur sporadically or as a result of inherited predisposition (as part of familial adenomatous polyposis, FAP). Whereas desmoid-type fibromatosis often present β-catenin overexpression (by activating CTNNB1 somatic variants or APC biallelic inactivation), the pathogenetic mechanisms in Gardner fibroma are unknown. We characterized in detail Gardner fibromas diagnosed in two infants to evaluate their role as sentinel lesions of previously unrecognized FAP. In the first infant we found a 5q deletion including APC in the tumor and the novel APC variant c.4687dup in constitutional DNA. In the second infant we found the c.5826_5829del and c.1678A>T APC variants in constitutional and tumor DNA, respectively. None of the constitutional APC variants occurred de novo and both tumors showed nuclear staining for β-catenin and no CTNNB1 variants. We present the first comprehensive characterization of the pathogenetic mechanisms of Gardner fibroma, which may be a sentinel lesion of previously unrecognized FAP families.

  14. Radiographic and histologic patterns of calcification in chondromyxoid fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Yamaguchi, Takehiko [Section of Orthopaedic Pathology, Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY (United States)]|[Department of Pathology, Dokkyo University School of Medicine, Mibu (Japan); Dorfman, H.D. [Section of Orthopaedic Pathology, Montefiore Medical Center/ Albert Einstein College of Medicine, Bronx, NY (United States)

    1998-10-01

    Objective. To evaluate the frequency of radiologic and histologic manifestations of matrix calcification in chondromyxoid fibromas. Patients. Forty-four cases of chondromyxoid fibroma were reviewed. The age range of the patients was 3-70 years (average 29 years). Results. Calcification was found microscopically in 15 cases (34.1%). In five cases (12.5%) it was demonstrated on plain films or CT. The age range of the patients with microscopic evidence of calcified matrix was 14-70 years (mean 46 years), while that of the patients with non-calcified lesions was 3-59 years (average 21 years). All but two of the patients who showed microscopic calcification in the tumors were over 40 years of age. Four microscopic patterns of calcification were observed: coarse granular, circumscribed, trabecular, and ``chicken-wire.``Conclusions. Calcification in chondromyxoid fibroma was found more frequently than in previously reported studies. There was a tendency for this phenomenon to occur in the tumors of older patients, particularly those over 40 years old, and in chondromyxoid fibromas situated in flat bones, including ribs. (orig.) With 6 figs., 3 tabs., 11 refs.

  15. Fibroma of tendon sheath of the infrapatellar fat pad

    Energy Technology Data Exchange (ETDEWEB)

    Hur, J. [College of Medicine, State University of New York Health Science Center at Syracuse, Syracuse, NY (United States); Damron, T.A. [Department of Orthopedic Surgery, 550 Harrison Center, Syracuse, NY (United States); Vermont, A.I. [Department of Radiology, State University of New York Health Science Center at Syracuse, Syracuse, NY (United States); Mathur, S.C. [Department of Pathology, State University of New York Health Science Center at Syracuse, Syracuse, NY (United States)

    1999-07-01

    We report on a 13-year-old boy who was found to have a fibroma of the tendon sheath associated with the patellar tendon and within Hoffa`s fat pad of the knee. This benign tumor has never been described in this location previously. The MRI characteristics are correlated with the histologic findings. (orig.) With 2 figs., 18 refs.

  16. Unique giant cardiac tumor in an infant: rhabdomyoma or fibroma?

    Science.gov (United States)

    Abid, Dorra; Hmida, Nadia; Daoud, Emna; Gargouri, Abdellatif; Kammoun, Samir

    2014-08-01

    We report a case of giant cardiac tumor diagnosed at fetal life and thought to be a fibroma. Six months later, a marked regression of the tumor size was observed. Diagnosis of rhabdomyoma was retrospectively made. Tuberous sclerosis was then suspected and MRI showed many signs of consistent diagnosis.

  17. Mineralized fibroma of the tendon sheath presenting as a bursitis

    Energy Technology Data Exchange (ETDEWEB)

    Le Corroller, Thomas; Champsaur, Pierre [Hopital Sainte-Marguerite, Service de Radiologie, Marseille (France); Faculte de Medecine de Marseille, Departement d' Anatomie, Marseille (France); Bouvier-Labit, Corinne [Hopital La Timone, Service d' Anatomopathologie, Marseille (France); Sbihi, Abderrahmane [Clinique Juge, Service de Chirurgie orthopedique, Marseille (France)

    2008-12-15

    We report on the clinical, imaging - including ultrasound, computed tomography, and magnetic resonance imaging - and histological features of a fibroma of the tendon sheath with mineralized chondroid and osseous metaplasia, presenting as a semimembranosus bursitis. The anatomical characteristics of the semimembranosus bursa are demonstrated by dissection in a cadaveric specimen and correlated with the imaging findings in our patient. (orig.)

  18. PSAMMOMATOID OSSIFYING FIBROMA OF THE PARANASAL SINUSES - AN EXTRAGNATHIC VARIANT OF CEMENTO-OSSIFYING FIBROMA - REPORT OF 3 CASES

    NARCIS (Netherlands)

    SLOOTWEG, PJ; PANDERS, AK; NIKKELS, PGJ

    1993-01-01

    Psammomatoid ossifying fibroma (POF) is a diagnostic designation for a sinonasal or orbital fibroosseous lesion characterized by numerous small round mineralized spherules lying in a fibroblastic stroma. We report 3 cases. One occurred in the frontal sinus of an 18-years-old male; 1 in the frontal s

  19. PSAMMOMATOID OSSIFYING FIBROMA OF THE PARANASAL SINUSES - AN EXTRAGNATHIC VARIANT OF CEMENTO-OSSIFYING FIBROMA - REPORT OF 3 CASES

    NARCIS (Netherlands)

    SLOOTWEG, PJ; PANDERS, AK; NIKKELS, PGJ

    1993-01-01

    Psammomatoid ossifying fibroma (POF) is a diagnostic designation for a sinonasal or orbital fibroosseous lesion characterized by numerous small round mineralized spherules lying in a fibroblastic stroma. We report 3 cases. One occurred in the frontal sinus of an 18-years-old male; 1 in the frontal s

  20. Cemento-ossifying Fibroma Of Paranasal Sinus Presenting Acutely As Orbital Cellulitis.

    Science.gov (United States)

    Khanna, Maneesh; Buddhavarapu, Shanker Rao; Hussain, Sheik Akbar; Amir, Emran

    2009-01-01

    Fibro-osseous lesions of the face and paranasal sinuses are relatively uncommon. These lesions have overlapping clinical, radiologic and pathologic features causing difficulty in diagnosis. Neoplastic fibro-osseous paranasal sinus lesions can be benign or malignant. The benign fibro-osseous lesions described are: ossifying fibroma (and its histologic variants) and fibrous dysplasia. The variants of ossifying fibroma differ in the nature of calcified material (i.e. cementum versus bone), in the location of the lesion (oral versus paranasal sinus or orbital), other morphologic variations (presence of psammomatoid concretions) and biologic behavior (aggressive versus stable). Presence of cementum or bone classifies the lesion as cementifying fibroma or ossifying fibroma respectively while lesions with mixture of both cementum and bone are called cemento-ossifying fibroma. We describe a case of a young adult male with cemento-ossifying fibroma of paranasal sinus presenting acutely as left orbital cellulitis with proptosis.

  1. Conservative management of a left ventricle cardiac fibroma in an asymptomatic child patient.

    Science.gov (United States)

    Ünsal, Handan; Ekici, Enver

    2015-07-01

    Primary cardiac tumors in infancy and childhood are rare and usually benign. Fibroma is the second most common bening cardiac tumor after rhabdomyoma. Surgery is required when fibromas cause ventricular outflow tract obstruction, ventricular dysfunction and life-threatening arrhythmia. This case report describes a 9-year-old asymptomatic male presenting with a giant left ventricular cardiac fibroma who was followed up using conservative treatment.

  2. Large right ventricular fibroma in a 6-month-old infant.

    Science.gov (United States)

    Horovitz, Alice; van Geldorp, Irene E; Roubertie, François; Thambo, Jean-Benoit

    2012-12-01

    This report describes the case of a 6-month-old girl with a large cardiac fibroma in the right ventricle. Ventricular tachycardia associated with the fibroma was successfully treated with amiodarone. At the age of 3 years, surgical resection was indicated because of right ventricular outflow tract obstruction caused by progression of the tumor. The fibroma was successfully resected, and further follow-up evaluation was uneventful.

  3. Desmoplastic fibroma of bone in a toe: Radiographic and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Ok Hwa; Kim, Seon Jeong; Kim Ji Yeon; Ryu, Ji Hwa [Inje University, Haeundae Paik Hospital, Busan (Korea, Republic of); Choo, Hye Jung [Dept. of Radiology, Inje University, Busan Paik Hospital, Busan (Korea, Republic of); Lee, In Sook [Dept. of Radiology, Busan National University Hospital, Busan (Korea, Republic of); Suh, Kyung Jin [Dept. of Radiology, Dongguk University, Gyeongju Hospital, Gyeongju (Korea, Republic of)

    2013-12-15

    Desmoplastic fibroma is a rare benign primary bone tumor that is histologically similar to the soft tissue desmoid tumor. It most often involves the mandible, large long bone or iliac bone. Desmoplastic fibroma in a toe has been extremely rarely reported. Authors report a rare case of desmoplastic fibroma of bone occurring in the distal phalanx of a foot, with descriptions of the radiographic and MRI findings, correlation of the radiologic and pathologic findings, and discussion on the differential diagnosis of the tumor.

  4. Ovarian fibroma with marked ascites and elevated serum levels of CA-125 in a young girl.

    Science.gov (United States)

    Sugiyama, Akihide; Urushihara, Naoto; Fukumoto, Koji; Fukuzawa, Hiroaki; Nagae, Hideki; Watanabe, Kentaro; Mitsunaga, Maki; Hasegawa, Shiro; Koyama, Masashi

    2011-05-01

    We report a case of ovarian fibroma with marked ascites and elevated serum CA-125 levels in a young girl. Ovarian fibromas are rare in children. They usually present as a solid mass and may be associated with ascites and elevated serum CA-125 levels. Because of their solid nature and these associations, they can be mistaken for a malignant tumor, resulting in unnecessary oophorectomy. Ovarian fibromas are benign neoplasms, and the prognosis is extremely good. Surgical management should be an ovarian-sparing tumor excision. Although uncommon in pediatric patients, ovarian fibromas should be included in the differential diagnosis of ovarian mass in children.

  5. Peripheral ameloblastic fibroma of the maxilla: report of a case and review of the literature.

    Science.gov (United States)

    Abughazaleh, Khaled; Andrus, Kevin M; Katsnelson, Alexander; White, Dean K

    2008-05-01

    Peripheral odontogenic lesions are considered to be rare within the classification of odontogenic tumors. Also referred to as extraosseous or soft tissue odontogenic tumors, peripheral odontogenic tumors share the same histopathologic characteristics of their central or intraosseous counterparts. Ameloblastic fibroma is a rare odontogenic tumor that arises from both odontogenic epithelium and connective tissue. Only 2 cases of peripheral ameloblastic fibroma have been reported in the English-language literature, one of which did not show the classic features of an ameloblastic fibroma. In this report, we describe a rare case of a peripheral ameloblastic fibroma in the maxilla of a 3-year-old girl.

  6. Psammomatoid Juvenile Ossifying Fibroma: A Case Report with Literature Review

    Directory of Open Access Journals (Sweden)

    Preeti Nair

    2010-01-01

    Full Text Available Psammomatoid Juvenile Ossifying Fibroma (PJOF is an uncommon neoplasm that is distinguished from the adult variant of ossifying fibromas on the basis of age, site, clinical behavior and microscopic appearance. It is seen in children younger than 15 years of age, and the maxilla is more commonly involved than the mandible. PJOF may exhibit erosion and invasion of the surrounding bone accompanied by rapid enlargement PJOF can be distinguished from other maxillofacial fibro-osseous lesions by its tendency to recur and its clinical mimicry of malignant bone tumors, but some clinical and histological features of PJOF overlap with the other fibro-osseous lesions as well. We report a case of a 15-year-old female patient with a painless apparently slow growing tumor in the left malar region, which occupied almost the whole of the left maxillary sinus, eroding the orbital border of the sinus.

  7. Conservative Management of Central Cemento-Ossifying Fibroma.

    Science.gov (United States)

    Gomes-Ferreira, Pedro Henrique Silva; Carrasco, Leandro Carlos; de Oliveira, Danila; Pereira, Járede Carvalho; Alcalde, Luis Fernando Azambuja; Faverani, Leonardo Perez

    2017-01-01

    Central cemento-ossifying fibroma is characterized by the combined production of osteoid and cementoid tissue. Radiographically, this lesion is presented as an outlined cortical and variable radiopaque spots, also can be present complete radiolucent or different degrees of radiopacity. The recommended treatment is curettage or enucleation, and the recurrence rate is less than 5%. Considering that surgical treatment is invasive, mainly in large lesions, this study aims to report a patient in whom conservative treatment was carried out by involving the preservation of teeth, with a long-term follow-up. A 48-year-old black female patient, diagnosed with central cemento-ossifying fibroma in mandible, treated conservatively and a 2 years of follow-up. It was concluded that the conservative treatment with a long term of follow-up for maintaining teeth was satisfactory.

  8. Chondromyxoid fibroma of the temporal bone: CT and MRI findings

    Energy Technology Data Exchange (ETDEWEB)

    Tarhan, N.C.; Yologlu, Z.; Tutar, N.U.; Coskun, M.; Agildere, A.M. [Baskent Univ. School of Medicine, Bahcelievler Ankara (Turkey). Dept. of Radiology; Arikan, U. [Baskent Univ. School of Medicine, Bahcelievler Ankara (Turkey). Dept. of Pathology

    2000-10-01

    We present the case of a 44-year-old woman with chondromyxoid fibroma of temporal bone origin. Since this is the least common bone tumor of cartilaginous origin, it is highly unusual to find this tumor in the skull. In fact, the literature describes 18 cases of this form of neoplasia arising in the skull, only 4 of these having originated in the temporal bone. To date, the radiological features of these tumors, and especially features detected using the latest imaging modalities, have not been described in detail. This report is unique in that it is the first to present a case of chondromyxoid fibroma of the temporal bone accompanied by detailed CT and MRI findings. (orig.)

  9. Collagenous fibroma of the arm: a report of two cases

    Energy Technology Data Exchange (ETDEWEB)

    Ogose, A.; Hotta, Tetsuo [Department of Orthopedic Surgery, Niigata University School of Medicine, Asahimachi 1, Niigata (Japan); Emura, Iwao [Department of Pathology, Niigata University School of Medicine (Japan); Higuchi, Takeshi [Department of Radiology, Niigata University School of Medicine (Japan); Kusano, Nozomu [Tominaga-Kusano Orthopedic Hospital, Kouno, Sanjyo (Japan); Saito, Hidehiko [Department of Orthopedic Surgery, Seirei Hamamatsu Hospital, Sumiyoshi 2, Hamamatsu 430-8558 (Japan)

    2000-07-01

    A recently proposed addition to fibrous tumors in soft tissue was first described as desmoplastic fibroblastoma and later renamed collagenous fibroma. This tumor is clinically and morphologically distinct and benign. However, only a few series have been reported, and the clinicopathologic features are not widely recognized. We present two cases of collagenous fibroma of the arm. Both patients presented with an enlarging, well-circumscribed and mobile soft tissue mass. Magnetic resonance imaging showed areas of low signal intensity on both T1- and T2-weighted sequences. Needle aspiration cytology revealed nondiagnostic samples because of the low cellularity of the tumors. Each of the resected tumors was composed of low-cellular spindle- to stellate-shaped cells in a fibrous matrix with clear margination. After the marginal excisions, no recurrences were observed. Clinicians should be aware of this entity to prevent overtreatment, because imaging findings and cytologic features are similar to those of desmoid tumor. (orig.)

  10. Giant Cell Fibroma of the Tongue: A Case Report

    Directory of Open Access Journals (Sweden)

    Farrokh Farhadi

    2014-11-01

    Full Text Available Giant cell fibroma of the tongue is a rare benign fibrous tumor of connective tissues in the oral cavity, very few of which have been reported. This benign neoplasm has a predilection for the gingiva and .usually occurs in women under 30. Since this tumor is clinically, and especially histopathologically, placed in the differential diagnosis list of benign and malignant mesenchymal tumors, its proper diagnosis is of great significance because widespread and unnecessary surgeries are avoided as a result. The aim of the present report is to present a case of the tumor in the tongue of a 65-year-old man. The fibroma is a benign fibrous tumor of connective tissues which is microscopically classified in differential diagnosis with other soft tissue tumors since its proper diagnosis prevents from extensive and unnecessary surgeries on the patient.

  11. MRI of fibrous cortical defect and non-ossifying fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Mishima, Yoshiko; Aoki, Takatoshi; Watanabe, Hideyuki; Nakata, Hajime; Hashimoto, Hiroshi; Nakamura, Toshitaka [Univ. of Occupational and Environmental Health, Kitakyushu, Fukuoka (Japan). School of Medicine

    1999-02-01

    Fibrous cortical defect and non-ossifying fibroma are the benign fibrous lesions of bone commonly involving children. Their diagnosis is usually done with radiography, and MR examinations are rarely performed. We evaluated MRI findings of 11 lesions in 10 cases of fibrous cortical defect and non-ossifying fibroma. Signal intensity of the lesions was varied and large lesions (2 cm<) tended to show heterogeneous signal intensity on both T1-weighted and T2-weighted images corresponding to a mixture of components including fibrous tissue, hemosiderin and foam cells. MRI helps to delineate the extent of the involved bone and to assess the various histological components of the lesions. However, their diagnosis is basically made on the radiographic findings and the role of MRI is limited. (author)

  12. Aspiration cytology of ameloblastic fibroma: a diagnostic challenge.

    Science.gov (United States)

    Kumar, Neeta; Jain, Shyama

    2003-08-01

    Ameloblastic fibroma of the jaw is a rare, benign mixed odontogenic tumor, having little tendency for local invasion and a low recurrence rate. Cytologic distinction from ameloblastoma, ameloblastic fibrosarcoma, and intraosseous adenoid cystic carcinoma is necessary, in view of the different biologic behavior. A painful, slow-growing swelling of the jaw in a 5-yr-old child clinicoradiologically considered as a benign cystic lesion was aspirated. Sheets of small monomorphic epithelial cells with peripheral palisading by columnar cells were seen on cytology smears. The striking feature was central hyaline globules in some tubules. A cytologic possibility of adenomatoid odontogenic tumor was suggested. Histopathology, however, confirmed it to be an ameloblastic fibroma. Copyright 2003 Wiley-Liss, Inc.

  13. Oncogenic osteomalacia associated with soft tissue chondromyxoid fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jeong Mi E-mail: jmpark@cmc.cuk.ac.kr; Woo, Young Kyun; Kang, Moo Il; Kang, Chang Suk; Hahn, Seong Tae

    2001-08-01

    Oncogenic osteomalacia is a rarely described clinical entity characterized by hypophosphatemia, phosphaturia, and a low concentration of 1,25-dihydroxyvitamin D{sub 3}. It is most often associated with benign mesenchymal tumor and can be cured with surgical removal of the tumor. In this paper, we present a case of oncogenic osteomalacia caused by chondromyxoid fibroma in the soft tissue of the sole of the foot in a 56-year-old woman.

  14. Congenital chondromyxoid fibroma of the ethmoid: case report

    Energy Technology Data Exchange (ETDEWEB)

    Mendoza, M.; Gonzalez, I.; Aperribay, M.; Nogues, A. [Servicio de Radiologia, Hospital Ntra. Sra. de Aranzazu/Arantzazuko Amaren Ospitalea, Donostia-San Sebastian, Gipuzkoa (Spain); Hermosa, J.R. [Servicio de Anatomia Patologica, Hospital Ntra. Sra. de Aranzazu/Arantzazuko Amaren Ospitalea, Donostia-San Sebastian, Gipuzkoa (Spain)

    1998-05-01

    This report describes a congenital case of chondromyxoid fibroma (CMF) arising from the ethmoid bone. We believe it to be the second case of congenital CMF that has been documented, and the third case of CMF arising in the ethmoid. We describe the radiographic features of this rare entity and indicate the necessity for careful correlation between radiographic and histological findings to distinguish CMF from chondrosarcoma. (orig.) With 3 figs., 5 refs.

  15. Ameloblastic fibroma: a case report in a 6 year old.

    Science.gov (United States)

    Garcia-Pola Vallejo, M; Gonsalez Garcia, M; Villalain Alvarez, L; Fresno Forcedello, M; Lopez-Arranz, J S

    2001-01-01

    A six-year-old boy was seen by his dentist for a tumor mass in the left mandibular region. The panograph revealed a multilocular radiotransparent lesion extending from the canine to the left mandibular ascending ramus with well defined borders. After biopsy, the lesion was enucleated via curettage of the bone bed. The lesion was diagnosed as ameloblastic fibroma. After six months, radiographs showed that the surgical defect had filled with new bone.

  16. Central Odontogenic Fibroma of Mandible: A Case report

    Directory of Open Access Journals (Sweden)

    Samaneh Bayat

    2016-03-01

    Full Text Available Background and Aims: Central odontogenic fibroma is a rare odontogenic neoplasm that originates from odontogenic ectomesenchyme. Most cases occur in the mandible and between the ages of 11 and 39 years. The neoplasm shows a definite female preponderance, with a ratio of 2.2:1 and has a very low recurrence rate. The aim of this article was to report a case of this rare lesion which was accidental found. Case Report: A 11-year-old female, during her orthodontic treatment and without any complain and any sign or symptoms, performed a panoramic image for assessing the permanent teeth buds. In the panoramic view a unilocular radiolucent lesion with well-defined and corticated borders in the right mandibular body region was evident. The lesion was treated with simple excision. Simple type of central odontogenic fibroma histopathologic features was observed in the microscopic view. Conclusion: Although the central odontogenic fibroma is a rare benign neoplasm, however, a careful evaluation of radiographic images is important for early detection of lesions because the patient may have no clinical symptoms such as swelling, pain and paresthesia.

  17. Cemento-ossyfying fibroma juvenile of the oral cavity.

    Science.gov (United States)

    Cecchetti, F; Luciani, F; Bramanti, E; Bartuli, F N; Ottria, L; Arcuri, C

    2010-01-01

    Fibro-osseous neoplasm remains somewhat controversial, and differing concept have been advanced regarding their nature and the proper terminology for them. Cemento-ossyfying fibroma juvenile (JOF) is a rare type of fibro-osseous tumor as also been included under the "umbrella" of cemento-ossyfying fibroma. The JOF is most often seen in patients who are between 5 and 15 years of age. With this work we emphasize the importance of a correct diagnostic approach. MATERIAL AND METHODS.: The case describes a form of cemento-ossyfying fibroma hight active and aggressive like JOF. The patient thirteen older showed from 2004 to 2008 three times the palatal lesion, it was performed with a incisional biopsy and excisional biopsy. The tumor were fixed in 10% buffered formalin embedded in paraffin cut into thick sections and stained with ematoxylineosin. The incisional biopsy was inadequate to formulate a correct diagnosis. The histological exams have showed for three times different aspects. Some authors in the past have suggested different classification. The COFs show different clinical, histological and radiographical patterns.

  18. Giant Cell Fibroma in a Two-Year-Old Child

    Directory of Open Access Journals (Sweden)

    Anna Carolina Volpi Mello-Moura

    2016-01-01

    Full Text Available The giant cell fibroma is a benign nonneoplastic fibrous tumor of the oral mucosa. It occurs in the first three decades of life in the mandibular gingiva, predominantly, showing predilection for females. This article reports a case of giant cell fibroma in a 2-year-old girl, which is an uncommon age for this lesion. The patient was brought for treatment at the Research and Clinical Center of Dental Trauma in Primary Teeth, where practice for the Discipline of Pediatric Dentistry (Faculty of Dentistry, University of São Paulo, Brazil takes place. During clinical examination, a tissue growth was detected on the lingual gingival mucosa of the lower right primary incisors teeth. The lesion was excised under local anesthesia and submitted to histological examination at the Oral Pathology Department of the Faculty of Dentistry, University of São Paulo, which confirmed the diagnosis of giant cell fibroma. There was no recurrence after 20 months of monitoring. This instance reinforces the importance of oral care from the very first months of life in order to enable doctors to make precocious diagnosis and offer more appropriate treatments for oral diseases, as well as to promote more efficient oral health in the community.

  19. Mucocele and fibroma: treatment and clinical features for differential diagnosis.

    Science.gov (United States)

    Valério, Rodrigo Alexandre; de Queiroz, Alexandra Mussolino; Romualdo, Priscila Coutinho; Brentegani, Luiz Guilherme; de Paula-Silva, Francisco Wanderley Garcia

    2013-01-01

    Mucocele is a benign lesion occurring in the buccal mucosa as a result of the rupture of a salivary gland duct and consequent outpouring of mucin into soft tissue. It is usually caused by a local trauma, although in many cases the etiology is uncertain. Mucocele is more commonly found in children and young adults, and the most frequent site is the lower inner portion of the lips. Fibroma, on the other hand, is a benign tumor of fibrous connective tissue that can be considered a reactionary connective tissue hyperplasia in response to trauma and irritation. They usually present hard consistency, are nodular and asymptomatic, with a similar color to the mucosa, sessile base, smooth surface, located in the buccal mucosa along the line of occlusion, tongue and lip mucosa. Conventional treatment for both lesions is conservative surgical excision. Recurrence rate is low for fibroma and high for oral mucoceles. This report presents a series of cases of mucocele and fibroma treated by surgical excision or enucleation and the respective follow-up routine in the dental clinic and discusses the features to be considered in order to distinguish these lesions from each other.

  20. MR findings of ossifying fibroma with pathologic correlation

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Won Kyun; Lee, Jeong Hoon; Kim, Kie Hwan [Korea Cancer Center Hospital, Seoul (Korea, Republic of)

    2002-03-01

    To compare the MR imaging findings of ossifying fibroma with the histopathologic findings. In eight patients (M:F=1.7; age range, 1-25 years) with pathologically proven ossifying fibroma, plain film and MR images were retrospectively analyzed in terms of signal intensity, homogeneity and patterns of contrast enhancement. The MR imaging findings and histopathology were correlated. Using 1.0-T and 1.5-T MR machines, axial T1 and T2 images and gadolinium-enhanced axial and sagittal T1 images were obtained. In all cases, iso-signal intensity to muscle was observed on T1-weighted images, and high signal intensity on T2-weighted images. After intravenous injection of gadolinium-DTPA in seven cases, intense contrast enhancement was seen in all lesions, which were homogenous on T1, T2, and enhanced MR images, Moderate cellularity of fibrous tissue, with even distribution of osteoid and an absence of secondary changes such as hemorrhage or cystic change were revealed by pathologic examination. Ossifying fibroma shows strong enhancement and homogenous signal intensity on MR images. The homogeneity of the MR signal depends on the even distribution of osteoid and an absence of secondary changes such as hemorrhage or cystic change.

  1. [Cardiac fibroma: A rare cause of sudden child death].

    Science.gov (United States)

    Humez, Sarah; Gibier, Jean-Baptiste; Recher, Morgan; Leteurtre, Stéphane; Leroy, Xavier; Devisme, Louise

    2015-10-01

    We report the case of a 3-year-old child who died from the consequences of a cardio-respiratory arrest despite reanimation procedures. Echocardiography and magnetic resonance imaging (MRI) revealed a mass of the free wall of the left ventricle. Autopsy confirmed the existence of a solitary myocardial tumor, well-circumscribed, firm, with a whitish and trabeculated cut surface. Histologically, the tumor consisted of bundles of spindle-shaped and regular cells mingling with collagen and elastic fibers, insinuating themselves between myocytes in periphery. Calcifications were present. After immunohistochemistry, the cells were highlighted by anti-actin smooth muscle antibody; but they were not highlighted by anti-desmin, anti-β catenin and anti-Ki67 antibodies. The diagnosis of cardiac fibroma was made. The primary cardiac tumors of child are rare and usually benign. They are essentially represented by rhabdomyoma and fibroma. Cardiac fibroma mostly occurs during the first year of life. It can be revealed by cardiac insufficiency, arrhythmia, chest pain or sudden death.

  2. Ameloblastic fibroma in the midline of mandible: a case report.

    Science.gov (United States)

    Mohapatra, P K; Choudhury, A R; Parkash, H

    2000-01-01

    The ameloblastic fibroma (AF) is a rare benign mixed odontogenic tumor. It is composed of both epithelial and mesenchymal elements, but lacks of any calcified dental structures. Most of these tumors occur in the mandible and appears preferentially in the posterior portion of the dental arch with molar area predominates over premolar area. It is important to differentiate the lesion from ameloblastoma, since unlike the latter, it does not exhibit a locally invasive growth pattern. It is a well-circumscribed lesion and does not require the radical excision that may be necessary to effect cure with ameloblastoma. The present case report describes a 15-year-old patient with an ameloblastic fibroma in the symphysis of the mandible, a rare reported site. In the beginning of the article an extensive review of the previously published literature on ameloblastic fibroma has been made. In the later part, the diagnosis, differential diagnosis, histology and therapeutic procedures and postoperative follow up of the present case have been described.

  3. Ameloblastic fibroma at the University of Nairobi Dental Hospital.

    Science.gov (United States)

    Chindia, M L; Akama, M K; Awange, D O

    2005-08-01

    To document the occurrence of cases of ameloblastic fibroma. A retrospective study. The Division of Oral Pathology and Oral Medicine histopathology laboratory at the Faculty of Dental Sciences, University of Nairobi, January 1991 to December 2000. Seven complete records of histopathologically confirmed cases of ameloblastic fibroma were identified. There were four male and three female cases with an age range of 10 to 22 years (mean=14 years). Remarkably, six of the cases had lesions in the molar regions of the mandible with a single case with a maxillary molar area lesion. One of the cases had the neoplasm associated with an unerupted tooth. From the clinical notes all the patients were managed by meticulous enucleation and curettage of the lesions. After follow up periods ranging from several months to eight years no recurrences had been recorded. Evidently ameloblastic fibroma is an uncommon neoplasm as noted in the earlier literature. Although the lesions can be quite extensive at the time of diagnosis, the recurrence rate appears to be relatively low if the neoplasms are meticulously extirpated.

  4. Cemento-ossyfying fibroma juvenile of the oral cavity

    Science.gov (United States)

    CECCHETTI, F.; LUCIANI, F.; BRAMANTI, E.; BARTULI, F.N.; OTTRIA, L.; ARCURI, C.

    2010-01-01

    SUMMARY Objectives Fibro-osseous neoplasm remains somewhat controversial, and differing concept have been advanced regarding their nature and the proper terminology for them. Cemento-ossyfying fibroma juvenile (JOF) is a rare type of fibro-osseous tumor as also been included under the “umbrella” of cemento-ossyfying fibroma. The JOF is most often seen in patients who are between 5 and 15 years of age. With this work we emphasize the importance of a correct diagnostic approach. Material and methods. The case describes a form of cemento-ossyfying fibroma hight active and aggressive like JOF. The patient thirteen older showed from 2004 to 2008 three times the palatal lesion, it was performed with a incisional biopsy and excisional biopsy. The tumor were fixed in 10% buffered formalin embedded in paraffin cut into thick sections and stained with ematoxylineosin. Results The incisional biopsy was inadequate to formulate a correct diagnosis. The histological exams have showed for three times different aspects. Conclusion Some authors in the past have suggested different classification. The COFs show different clinical, histological and radiographical patterns. PMID:23285378

  5. Expressão imuno-histoquímica da vimentina e do HHF-35 em fibroma de células gigantes, hiperplasia fibrosa e fibroma da mucosa oral Immunohistochemical expression of vimentin and HHF-35 in giant cell fibroma, fibrous hyperplasia and fibroma of the oral mucosa

    Directory of Open Access Journals (Sweden)

    Márcia Cristina da Costa Miguel

    2003-03-01

    Full Text Available O fibroma de células gigantes, a hiperplasia fibrosa e o fibroma constituem algumas das mais freqüentes lesões fibrosas orais, compartilhando características clínicas e histopatológicas. Este estudo teve o objetivo de investigar a imunorreatividade das células gigantes estreladas mono, bi ou multinucleadas, características do fibroma de células gigantes e, ocasionalmente presentes na hiperplasia fibrosa e no fibroma, a anticorpos anti-vimentina e anti-actina de músculo (HHF-35, visando detectar características fenotípicas destas células. Os resultados demonstraram que na maioria dos casos houve imunorreatividade para a vimentina, sugerindo um fenótipo fibroblástico para estas células.The giant cell fibroma, fibrous hyperplasia and fibroma are the most frequent fibrous oral lesions, sharing clinical and histopathological features. The purpose of this study was to investigate the immunoreactivity of the large stellate-shaped mononuclear and multinucleated cells, reported as the most characteristic histological feature of the giant cell fibroma but present occasionally in fibrous hyperplasia and fibroma, for the antibodies vimentin and HHF-35 in order to detect phenotypical characteristic of these cells. The results showed in the most of cases positive staining for vimentin, suggesting a fibroblast phenotype for these cells.

  6. Radiographic Differential Diagnosis Between The Fibrous Dysplasia And The Ossifying Fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Karp Shik [Dept. of Dental Radiology, College of Dentistry, Kyungpook National University, Daegu (Korea, Republic of)

    1999-02-15

    The author observed and compared the radiographic features of 49 cases of the fibrous dysplasia and 14 cases of the ossifying fibroma in the osteoblastic or mature stage radiologically and histopathologically. The obtained results were as follows: 1. Fibrous dysplasia occurred most frequently in the 2nd decade, but ossifying fibroma in the 3rd and 4th decades, and both lesions occurred with slight predilection in females. 2. In most cases, chief complaints were painless facial swelling. And 61.1% of fibrous dysplasia occurred in the maxilla, 92.9% of ossifying fibroma in the mandible, and most of these lesions occurred in the premolar-molar region. 3. In the mandibular lesions, ossifying fibroma was shown more oval and round shape, but fibrous dysplasia was shown fusiform shape. 4. Fibrous dysplasia was shown homogeneously distributed, complete radiopaque shadow at 63%, and ossifying fibroma was shown concentric, mixed appearance of radiolucent and radiopaque shadow at 92.9%. 5. Fibrous dysplasia was entirely shown poorly outlined and blended to normal surrounding bone, but ossifying fibroma was shown well-defined border. 6. Cortical thinning and expansion were observed in these lesions, but degree of cortical expansion was more severe in ossifying fibroma than fibrous dysplasia. 7. Loss of lamina dura, tooth displacement, and displacement of mandibular canal were observed in both lesions, but root resorption was observed in ossifying fibroma only.

  7. Giant left ventricular fibroma presenting as ventricular tachycardia in a child.

    Science.gov (United States)

    Khan, Muhammad Arif; Saeedi, Abdul Raoof Al; Tayeab, Hyfeah Al; Momenah, Tarek

    2014-06-01

    We present a rare case of giant left ventricular apical fibroma presenting as recurrent ventricular tachycardia in a 14-month-old girl. The diagnosis was made by echocardiography and chest computed tomography, and confirmed by histopathology. The fibroma was resected surgically, and the patient followed up for 4 years.

  8. A case of haemoptysis due to endobronchial fibroma, a rare benign tumour of lung

    Directory of Open Access Journals (Sweden)

    Das Sibes

    2008-01-01

    Full Text Available A case of recurrent haemoptysis due to fibroma is described in a 55 years old male patient. Clinical examination revealed anaemia and bilateral basal crepitations. Chest X - ray showed no abnormality. Bronchoscopy revealed polypoid fibroma in left main bronchus. It was removed bonchoscopically with no recurrence during 12 months follow up.

  9. Desmoplastic fibroma of the rib with cystic change: a case report and literature review

    Energy Technology Data Exchange (ETDEWEB)

    Okubo, Taketo [Juntendo University, Department of Orthopaedic Surgery, School of Medicine, Tokyo (Japan); Juntendo University, Department of Human Pathology, School of Medicine, Bunkyo-ku, Tokyo (Japan); Saito, Tsuyoshi [Juntendo University, Department of Human Pathology, School of Medicine, Bunkyo-ku, Tokyo (Japan); Takagi, Tatsuya; Suehara, Yoshiyuki; Kaneko, Kazuo [Juntendo University, Department of Orthopaedic Surgery, School of Medicine, Tokyo (Japan)

    2014-05-15

    Desmoplastic fibroma (DF) is a rare, locally aggressive, solitary tumor microscopically composed of well-differentiated myofibroblasts with abundant dense collagen deposition. The most common sites are the long tubular bones and mandible. To our knowledge, only five cases of DF in the ribs have been reported. Here, we report a case of DF in this rare location with unusual radiological findings. A 40-year-old man presented with a 4-year history of swelling of the right chest wall. Radiographs revealed a mass at the right 9th rib, and computed tomography demonstrated a mass of 14 x 12 x 8 cm at the right 9th rib with expanded cystic change and marked calcification that appeared to have arisen from the bone. Open biopsy suggested DF. Total excision was performed, and the chest wall was reconstructed. The surgical specimen was a yellowish tumor with multilocular cystic change containing a viscous liquid. The tumor was composed of a proliferation of less-atypical spindle-shaped cells in a collagenous background. The cystic change was observed in the extra-osseous lesion. No β-catenin cytoplasmic/nuclear accumulation was detected, and no β-catenin or GNAS genetic mutations were detected. A final diagnosis of DF was made on the basis of the pathological and radiological findings. The patient was successfully treated with total excision of the tumor with no evidence of recurrence 6 months after surgery. (orig.)

  10. Literature survey on epidemiology and pathology of cardiac fibroma

    Directory of Open Access Journals (Sweden)

    Torimitsu Suguru

    2012-03-01

    Full Text Available Abstract Background Although cardiac fibroma has been regarded as benign tumor, it presents various symptoms and may lead to death. Unfortunately, only a few studies have reported the epidemiology, embryology, and histopathology of the tumor, and the factors predicting poorer outcome are still obscured. Methods In July 2011 we searched for English and Japanese cases of cardiac fibroma using the PubMed and IgakuChuoZasshi databases. We then extracted and sampled raw data from the selected publications in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA style as much as was possible. Results Details of a total of 178 patients with cardiac fibroma were retrieved. The mean age was 11.4 years (median: 2.8 years. Tumor sizes ranged from 8.0 to 150.0 mm (mean 53.1 mm. The left ventricle was found to be the most common site associated with the tumor at a rate of 57.3%, followed by the right ventricle, and interventricular septum. The highest mortality was found in patients with septal involvement (58.6%. In all, 111 patients survived among the 160 patients with a recorded outcome. A younger age of the patient at the time of diagnosis was associated with a decreased survival rate. In addition, a significant positive association was found between ages for patients younger than 17 years of age and the diameter of the tumor at the time of diagnosis (r = 0.341, P = 0.006. Conclusions Both the younger age of patients at the time of diagnosis and septal involvement can be regarded as factors significantly indicating a poor prognosis. Furthermore, our statistical analyses support the following hypotheses. First, the high ratio of tumor-to-heart size may generate low cardiac output and therefore lead to poor outcome. Second, the ratio of the sites where cardiac fibroma occurred corresponds with the ratio of the muscular weight of the cardiac chamber. Third, cardiac fibroma involving the interventricular septum more

  11. Imaging in the diagnosis of cemento-ossifying fibroma: a case series.

    Science.gov (United States)

    Mithra, R; Baskaran, Pavitra; Sathyakumar, M

    2012-01-01

    Cemento-ossifying fibroma is a benign fibro-osseous lesion belonging to the same category as fibrous dysplasia and cementifying dysplasia. These are slow-growing lesions that are seen in the third and fourth decades of life. Both the ossifying fibroma and cemento-ossifying fibroma represent two extremes of the same disease process since histologically both contain bone and cementum. However, the term cemento-ossifying fibroma is justified on the basis of clinical and radiological correlation. Radiographs have become an essential tool in the diagnosis of lesions in the jaw, where the anatomy is complex. Nowadays, CT provides information for diagnosis as well as treatment planning. In this case series, we report three cases of cemento-ossifying fibroma that were histologically confirmed and discuss the imaging findings.

  12. Imaging in the Diagnosis of Cemento-Ossifying Fibroma: A Case Series

    Directory of Open Access Journals (Sweden)

    R Mithra

    2012-01-01

    Full Text Available Cemento-ossifying fibroma is a benign fibro-osseous lesion belonging to the same category as fibrous dysplasia and cementifying dysplasia. These are slow-growing lesions that are seen in the third and fourth decades of life. Both the ossifying fibroma and cemento-ossifying fibroma represent two extremes of the same disease process since histologically both contain bone and cementum. However, the term cemento-ossifying fibroma is justified on the basis of clinical and radiological correlation. Radiographs have become an essential tool in the diagnosis of lesions in the jaw, where the anatomy is complex. Nowadays, CT provides information for diagnosis as well as treatment planning. In this case series, we report three cases of cemento-ossifying fibroma that were histologically confirmed and discuss the imaging findings.

  13. Surface chondromyxoid fibroma of the distal ulna: unusual tumor, site, and age.

    Science.gov (United States)

    Abdelwahab, Ibrahim Fikry; Klein, Michael J

    2014-02-01

    Chondromyxoid fibroma (CMF) is a rare benign cartilage congener tumor comprising less than 1 % of primary bone tumors. Although the age range is wide, it is most commonly seen in the second and third decades. The most frequent location of CMF is in the long tubular bones of the lower extremities, particularly the proximal tibia and distal femur. Although the majority of chondromyxoid fibromas present as intramedullary tumors, a subgroup of chondromyxoid fibromas arising as surface lesions of the bone has recently been described. These are associated with an older mean age and an increased incidence of matrix calcifications. Chondromyxoid fibromas are rare in the distal ulna. We report a CMF presenting as a surface lesion of the distal metaphysis of the left ulna in a 41-year-old woman. We reviewed the literature on chondromyxoid fibromas involving the ulna and found that out of 22 cases, 1 was in the distal ulna, 13 in the proximal ulna, and in the remaining 8 the ulnar sites were unspecified. No case of chondromyxoid fibroma in the published literature had been designated as a surface lesion. Our own unpublished data include 70 chondromyxoid fibromas, 4 of which are in the ulna. Two of these are in the distal portion.

  14. Expression of tenascin and nucleolar organizer region in ameloblastoma and ameloblastic fibroma.

    Science.gov (United States)

    Carnelio, Sunitha; Vij, Hitesh

    2010-03-01

    The aim of this study was to assess the expression, distribution and comparison of tenascin, a glycoprotein of the extracellular matrix in ameloblastoma and ameloblastic fibroma, both odontogenic neoplasms with diverse biological behavior and to understand the proliferative activity by using the morphometric analysis. Paraffin embedded tissue from 25 cases of odontogenic tumors i.e., ameloblastoma (n = 15) and ameloblastic fibroma (n = 10) were used. The expression of tenascin was evaluated using immunohistochemistry. Morphometric analysis of nucleolar organizer regions (NORs) from ameloblastoma and ameloblastic fibroma was carried out by silver staining. A heterogeneous expression of tenascin was found in ameloblastoma which was mainly localized at the epithelial-mesenchymal interface and a patchy distribution was observed in the stroma (80%), while strong positivity was observed in the stroma and at the basement membrane zone of ameloblastic fibroma (100%). argyrophilic nucleolar organizer regions (AgNORs) revealed higher mean counts in ameloblastoma (3.093 +/- 0.902) when compared with those of ameloblastic fibroma (1.553 +/- 0.250). Ameloblastoma presented more than two NORs (two to five) per nucleus in majority of the cells, while ameloblastic fibroma exhibited only one NORs per nucleus. Expression of tenascin in these neoplasms suggest that it could play a role in epithelial- mesenchymal interaction, while AgNORs reveal that ameloblastomas are more aggressive when compared with ameloblastic fibromas.

  15. Chondromyxoid fibroma of C1: first case report

    OpenAIRE

    Ericson Sfreddo; Asdrubal Falavigna; Vinícius Borges Soares; Silva,Silvia Chaves e; André Nesi; Vinícius Carraro do Nascimento; Pedro Guarise da Silva

    2012-01-01

    BACKGROUND: Chondromyxoid fibroma (CMF) is a rare, benign primary bone tumor. The cervical spine is an uncommon site for this tumor, with only 10 reported cases to date and none involving the first cervical vertebra (C1). CASE REPORT: Female patient, 25-year-old monozygotic female twin, presented with cervical pain. Radiographic imaging demonstrated a contrast-enhanced, right-sided lytic lesion of the insufflated type in C1, with a punched-out appearance and extending to the anterior arch. A ...

  16. Peripheral cemento-ossifying fibroma: Report of a recurrence case.

    Science.gov (United States)

    Sah, Kunal; Kale, Alka D; Hallikerimath, Seema; Chandra, Sunira

    2012-04-01

    Peripheral cemento-ossifying fibroma [PCOF] is a reactive gingival overgrowth occurring frequently in the maxillary anterior region in teenagers and young adults. Here, we report a case of POCF in a 13-year-old male, which was previously surgically excised and had recurred after a period of 9 months. PCOF should be considered in differential diagnosis of such reactive hyperplastic lesions originating from the gingiva. Hence, early diagnosis with proper surgical excision and aggressive curettage of the adjacent tissues are essential for prevention of recurrence.

  17. Ameloblastic fibroma in one-year-old girl.

    Science.gov (United States)

    Munde, Anita D; Karle, Ravindra R; Kale, Ujwala B

    2013-01-01

    Ameloblastic fibroma (AF) is a relatively rare, slow growing benign mixed odontogenic tumor, comprising of 1.5-4.5% of all odontogenic tumors. It is usually asymptomatic except for the eventual expansion of the jaw. AFs are most common in adolescents and young adults, mostly affecting the mandible as a well-defined uni or multilocular radiolucency. The effective surgical treatment includes enucleation and curettage of the surrounding bone and removal of the affected teeth. Although recurrence of AF is rare, a long term follow up is recommended. This report describes a 1-year-old girl with AF in the mandible and discusses its clinical, radiographic and histological findings.

  18. Ameloblastic fibroma diagnosis, treatment and propensity for misidentification.

    Science.gov (United States)

    Gish, Joshua E; Lessin, Michael E

    2013-04-01

    We present a case of a young male with a radiolucency of the posterior mandible that was diagnosed as an ameloblastic fibroma, a mixed lesion derived from odontogenic epithelium and ectomesenchyme. This case report highlights a potential pitfall of this entity that may lead to inaccurate identification and treatment. Initial frozen section analysis yielded a diagnosis of odontogenic myxoma due to histologic similarities. Our report and discussion help to reacquaint the general practitioner with this entity and emphasize the need for routine screening radiographs and close clinical correlation whenever a microscopic diagnosis is rendered.

  19. Sudden unexpected infant death due to fibroma of the heart.

    Science.gov (United States)

    Meissner, C; Minnasch, P; Gafumbegete, E; Reiter, A; Gerling, I; Oehmichen, M

    2000-05-01

    A 7-month-old previously healthy female infant was found dead in her crib by her mother shortly after having been laid down to sleep following the noontime feeding. Because the child did not suffer from an acute illness and no other evidence pointed to a cause of death, it was initially assumed by the police that she had died of sudden infant death syndrome. At autopsy, however, the cause of death was determined to be cardiac arrhythmia secondary to fibroma of the heart.

  20. Chondromyxoid Fibroma of the Sternum in a 63-Year-Old Woman.

    Science.gov (United States)

    Kilic, Dalokay; Findikcioglu, Alper; Tepeoglu, Merih; Vural, Cigdem

    2015-08-01

    Primary chondromyxoid fibroma is a benign bone tumor. Its localization in the sternum is quite rare; we found only 6 relevant reports. We report our diagnosis and treatment of a chondromyxoid fibroma in the sternum of a 63-year-old woman. The patient underwent subtotal sternectomy and chest-wall reconstruction with use of a titanium rib bridge system and Prolene mesh. The patient's clinical course was uneventful, and she had no local recurrence 41 months postoperatively. Our review herein of the 6 previous cases reveals that our patient is the oldest thus far to have been diagnosed with a sternal chondromyxoid fibroma.

  1. Cemento-ossifying fibroma presenting as a posterior fossa mass lesion.

    Science.gov (United States)

    Kansal, Ritesh; Sharma, Arpit; Gaikwad, Ninad; Mahore, Amit; Goel, Atul

    2010-04-01

    Cemento-ossifying fibromas are benign lesions of the jaw, which arise from the periodontal membrane. Histopathologically these are composed of fibrous tissues with calcified structures resembling bone and cementum. Surgical resection is the treatment of choice. They have rarely been reported in the ethmoid sinus, maxillary sinus and sphenoid sinus Mastoid bone is an extremely rare site of such tumors. Only one case of cemento-ossifying fibroma of petromastoid bone has been reported before. We present a case of cementoossifying fibroma involving the petromastoid bone, with the large intracranial component causing compression on the cerebellum. This unique case may provide insight into the etiopathogenesis of these tumors.

  2. Cemento-ossifying fibroma of maxillary antrum in a young female patient.

    Science.gov (United States)

    Singhal, A; Ram, R; Singhal, P; Bhatnagar, S; Das, U M

    2011-12-01

    The cemento-ossifying fibroma is classified as a fibro-osseous lesion of the jaws. It commonly presents as a progressively growing lesion that can attain an enormous size with resultant deformity if left untreated. The cemento-ossifying fibroma is a central neoplasm of bone as well as periodontium which has caused considerable controversy because of controversy regarding terminology and the criteria for its diagnosis. This case report describes a female patient with cemento-ossifying fibroma involving maxillary antrum. The clinical, radiographic and histological features as well as the surgical findings are presented.

  3. A huge chondromyxoid fibroma of the nasal cavity in a newborn baby.

    Science.gov (United States)

    Yoo, Young Tae; Park, Joo Hyun; Sunwoo, Woong Sang; Rhee, Chae-Seo

    2012-08-01

    Chondromyxoid fibroma is a rare benign tumor that usually occurs in the long bones. A 2-month newborn presented with huge masses in the both nasal cavities, which turned out to be chondromyxoid fibroma. The masses originated from both inferior turbinates. Total turbinectomy on the left side and submucosal mass excision on the right side were performed. No recurrence or new lesion was observed during the 2 years of follow up. We report here on a rare case of nasal cavity chondromyxoid fibroma in a neonate and we review the relevant literature.

  4. Fibroma ameloblástico versus quiste folicular hiperplásico Ameloblastic fibroma versus hyperplastic follicular cyst

    OpenAIRE

    Azúa-Romeo, J; E. Saura Fillat; T. Usón Bouthelier; M. Tovar Lázaro; J. Azúa Blanco

    2004-01-01

    Resumen: El fibroma ameloblástico (FA) es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF), el segundo quiste odontogénico en frecuencia, está compuesto exclusivamente por tejido conjuntivo laxo (mesénquima), si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de...

  5. Cystic Shape Cemento-Ossifying Fibroma of Ethmoid Sinus.

    Science.gov (United States)

    Shejbal, Dražen; Vonsović, Gabrijela; Baudoin, Tomislav; Vagic, Davor

    2015-06-01

    Cemento-ossifying fibromas are a group of rarely occurring benign tumours, developing from the periodontal membrane and varying considerably in appearance and in the progress of the disease. Their common feature is higher or lower production of cemental tissue. In most cases the tumours are small because their cementoma mature quickly and become inactive, which causes the tumour to stop growing. They develop most frequently in the mandible and also in the maxilla. Other sites, such as paranasal cavities, soft tissues and bones of the head, are extremely rare. The case of a cemento-fibrosing tumour with psammoma infiltrations, developing from the ethmoid sinus in a nine-year-old girl is reported. Due to frontal headaches and sight defects as well as impaired vision on the right side, NMR was done, which showed a mucocele of the front and rear ethmoid with destruction of the orbital wall and a breakthrough into the orbit. The right maxillary sinus showed a visible retention and a thickened mucous membrane. A rhinoscopy revealed a ball-shaped spherical mass in the medial nasal meatus, which was defined as concha bullosa. An endoscopic examination showed that the tumour protruded in front of the medium nasal concha into the right nasal cavity, softened the ethmoid roof, penetrated toward the base of the skull, adhered and pushed the orbit. It was removed by FESS technique, and PHD revealed subsequently that it was not a mucocele but a cemento-ossifying fibroma.

  6. Cross-sectional imaging patterns of desmoplastic fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Mahnken, A.H.; Nolte-Ernsting, C.C.; Wildberger, J.E.; Guenther, R.W. [Dept. of Diagnostic Radiology, University Hospital, University of Technology, Aachen (Germany); Wirtz, D.C. [Dept. of Orthopaedics, University Hospital, University of Technology, Aachen (Germany)

    2001-07-01

    The aim of this study was to work out the cross-sectional imaging characteristics of desmoplastic fibroma (DF). In 3 patients with histologically proven DF, the imaging characteristics obtained with cross-sectional techniques were reviewed retrospectively. Radiographs and CT scans were available in all patients, and plain and contrast-enhanced MR examinations in 2 patients. Compared with conventional radiographs, CT allowed more accurate assessment of the extent of bone destruction including cortical breakthrough and articular invasion. Intramedullary tumor growth and soft tissue extension was best detected with MRI. Apart from heterogeneity on MR images, DF displayed nonspecific low signal intensity on unenhanced T1-weighted images and an intermediate to high signal intensity including areas of low intensity on T2-weighted images. Desmoplastic fibroma showed a distinct, inhomogeneous gadolinium enhancement. Although cross-sectional imaging features of DF are nonspecific, some MR characteristics, such as inhomogeneous contrast enhancement and the presence of low-intensity regions on T2-weighted images, are helpful in determining the differential diagnosis. Cross-sectional imaging of DF is useful for local staging of the tumor because it provides valuable information about the extent of bone destruction as well as medullary and extraosseous spread. (orig.)

  7. Treatment of large ameloblastic fibroma: a case report.

    Science.gov (United States)

    Vasconcelos, Belmiro C E; Andrade, Emanuel S S; Rocha, Nelson S; Morais, Hécio H A; Carvalho, Ricardo W F

    2009-06-01

    Ameloblastic fibroma (AF) is an extremely rare true mixed benign tumor that can occur in either the mandible or the maxilla, but is most frequently found in the posterior region of the mandible. It usually occurs in the first two decades of life and is associated with tooth enclosure, causing a delay in eruption or altering the dental eruption sequence. AF is diagnosed on routine radiographic evaluation and is clinically and radiographically similar to ameloblastic fibrodontoma and odontoma, which makes an accurate diagnosis mandatory. There is controversy in the literature as to whether treatment should be conservative or agressive. A conservative treatment strategy, such as enucleation and curettage, is usually sufficient. However, extensive lesions require radical treatment. We describe a case of ameloblastic fibroma with a very unusual clinical manifestation: it demonstrated considerable extension but no associated impacted tooth, was located in the anterior region of the mandible, and became symptomatic in the fifth decade of life. A radical surgical approach was taken, with immediate reconstruction.

  8. Fibroma digital infantil: presentación de un caso

    Directory of Open Access Journals (Sweden)

    Nery Romero Rojas

    2011-01-01

    Full Text Available El fibroma digital infantil o fibroma por cuerpos de inclusión es una entidad de rara incidencia, que se caracteriza por una proliferación benigna de células miofibroblásticas que forman nódulos en el dorso de los dedos de manos o pies de los niños. Tiene una imagen histológica muy característica -los cuerpos de inclusión citoplasmática- y una tendencia a la recurrencia; algunos pueden regresionar espontáneamente sin tratamiento. Se presenta el caso de un niño de 4 meses de edad, que desde el nacimiento presentó un tumor en el dorso de la falange distal del tercer dedo del pie derecho. Se extirpó el tumor de 1,5 x 1,3 x 0,6 cm que a la histología mostró una proliferación de haces entrelazados de células fusiformes con núcleos vesiculosos, en cuyo citoplasma presentaba cuerpos de inclusión eosinofílicos teñidos con la coloración tricrómica de Masson y que a la inmunohistoquímica se tiñeron con vimentina, actina y desmina.

  9. Low-grade osteosarcoma arising from cemento-ossifying fibroma: a case report.

    Science.gov (United States)

    Lee, Yong Bin; Kim, Nam-Kyoo; Kim, Jae-Young; Kim, Hyung Jun

    2015-02-01

    Cemento-ossifying fibromas are benign tumors, and, although cases of an aggressive type have been reported, no cases of cemento-ossifying fibroma transforming into osteosarcoma have been documented previously. Low-grade osteosarcoma is a rare type of primary bone tumor, representing 1%-2% of all osteosarcomas. A 45-year-old female patient was diagnosed with cemento-ossifying fibroma, treated with mass excision several times over a period of two years and eight months, and followed up. After biopsy gathered because of signs of recurrence, she was diagnosed with low-grade osteosarcoma. The patient underwent wide excision, segmental mandibulectomy, and reconstruction with fibula free flap. The aim of this report is to raise awareness of the possibility that cemento-ossifying fibroma can transform into osteosarcoma and of the consequent necessity for careful diagnosis and treatment planning.

  10. Intra-articular fibroma of tendon sheath arising in the acromioclavicular joint.

    Science.gov (United States)

    Glover, McKinley; Chebib, Ivan; Simeone, F Joseph

    2014-05-01

    Fibroma of the tendon sheath, a rare benign soft tissue tumor that most often occurs in the distal upper extremities (hands and wrist), is exceedingly rare to present as an intraarticular mass. Presented here is the first case in the English literature, to our knowledge, of a fibroma of the tendon sheath arising in the acromioclavicular joint. The patient presented with recurrent shoulder pain with activity without antecedent trauma. Radiographs were essentially normal. MR images demonstrated a lobulated, heterogeneous mass with contrast enhancement arising from the acromioclavicular joint. Following surgical resection, histopathology revealed hypocellular collagen matrix with spindle-shaped fibroblasts, confirming the diagnosis of fibroma of tendon sheath. The imaging features of the fibroma of the tendon sheath and a brief review of the literature are presented.

  11. An Unusually Large Irritation Fibroma Associated with Gingiva of Lower Left Posterior Teeth Region

    Science.gov (United States)

    Kulkarni, Sunita; Sonule, Sonal; Rathod, Usha

    2016-01-01

    Fibroma is a benign tumor of oral cavity, with usually the tongue, gingiva, and buccal mucosa being the most common sites. Females are twice more likely to develop fibroma than males. The intraoral fibroma typically is well demarcated; and its size can vary from millimeter to few centimeters. Intraorally the growth is attached to the mucosa by means of a peduncle. Fibroma is generally slow growing, painless, smooth surface lesion and the color is slightly paler than the adjacent healthy tissue. Treatment usually requires total excision and recurrence is rare. Here we present a case of 37-year-old female patient reported to the Department of Oral Medicine and Radiology with the chief complaint of a growth in the lower left posterior teeth region 3 months earlier. PMID:28116177

  12. Malignant transformation of ameloblastic fibroma to ameloblastic fibrosarcoma: case report and review of the literature.

    Science.gov (United States)

    Kobayashi, Kazuo; Murakami, Ryuichi; Fujii, Tohru; Hirano, Akiyoshi

    2005-10-01

    Ameloblastic fibrosarcoma is a rare malignant odontogenic tumour and is regarded as the malignant counterpart of the ameloblastic fibroma. The epithelial component remains benign, but the mesenchymal component becomes malignant. The diagnosis is made by histopathology. The case of a 26-year-old man who underwent curettage of an ameloblastic fibroma and died of an ameloblastic fibrosarcoma is presented, and the course of malignant transformation is analysed retrospectively. One-third of ameloblastic fibrosarcoma cases seem to have developed from recurrent ameloblastic fibromas. Knowledge of the malignant potential in the mesenchymal spindle cells of ameloblastic fibroma will assist in determining the management of these benign tumours, and may prevent malignant transformation to ameloblastic fibrosarcoma.

  13. Ameloblastic fibroma of the anterior maxilla presenting as a complication of tooth eruption: a case report.

    Science.gov (United States)

    McGuinness, N J; Faughnan, T; Bennani, F; Connolly, C E

    2001-06-01

    Ameloblastic fibroma is a rare mixed odontogenic tumour, which is extremely uncommon in the anterior maxillary region. A case report is presented where failure of eruption of an upper central incisor was the presenting feature.

  14. Solitary sclerotic fibroma of the skin: degenerated sclerotic change of inflammatory conditions, especially folliculitis.

    Science.gov (United States)

    Chang, S N; Chun, S I; Moon, T K; Park, W H

    2000-02-01

    Two cases showing changes of sclerotic fibroma developed in association with an inflammatory process, especially folliculitis. The lesion in the first case showed a well-circumscribed, nonencapsulated nodule in the dermis, which consisted of a perifollicular fibrotic area and a peripheral sclerotic area. In addition to the usual findings of sclerotic fibroma, spindle cells were heavily infiltrated in a storiform and fascicular pattern around the degenerated hair follicle, suggestive of dermatofibroma. The lesion in the second case showed the typical findings of sclerotic fibroma in association with folliculitis and hair follicle remnants. Our observations suggest that solitary sclerotic fibroma of the skin may be a degenerated or sclerotic end stage of other fibrous conditions, such as dermatofibroma, and that it may be induced by inflammation, especially folliculitis.

  15. A clinico‑pathologic review of 56 cases of ossifying fibroma of the ...

    African Journals Online (AJOL)

    2014-01-07

    Jan 7, 2014 ... Objective: This study aims at contributing to the definitive diagnosis of ossifying fibroma .... cases [Figure 2]; (b) predominantly globular (small, oval, .... is present in dentin matrix in dentinogenesis imperfecta associated with.

  16. Introduction to Extra Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Rizzo, Thomas G.; /SLAC

    2010-04-29

    Extra dimensions provide a very useful tool in addressing a number of the fundamental problems faced by the Standard Model. The following provides a very basic introduction to this very broad subject area as given at the VIII School of the Gravitational and Mathematical Physics Division of the Mexican Physical Society in December 2009. Some prospects for extra dimensional searches at the 7 TeV LHC with {approx}1 fb{sup -1} of integrated luminosity are provided.

  17. A massive sinonasal psammomatoid variant of juvenile ossifying fibroma: Report of a rare entity

    OpenAIRE

    VR Guttikonda; Taneeru, S; Gaddipati, R; Madala, J

    2013-01-01

    Juvenile ossifying fibroma (JOF) is an uncommon, benign, bone-forming neoplasm with an aggressive local growth that is distinguished from other fibro-osseous lesions primarily by its age of onset, clinical presentation and aggressive behaviour. JOF is considered as a variant of the ossifying fibroma (OF) and the former includes psammomatoid JOF (PsJOF) and Trabecular JOF (TrJOF). Both variants involve the craniofacial bones with the trabecular variant being more common in the jaws and the psa...

  18. A Rare Case of Epiphyseal Chondromyxoid Fibroma of the Proximal Tibia

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Yun Sun; Kim, Byoung Suck; Lee, Seok Hoon; Song, Baek Yong [Eulji Hospital, Eulji University College of Medicine, Seoul (Korea, Republic of); Park, Yong Koo [Kyung Hee University College of Medicine, Seoul (Korea, Republic of)

    2011-11-15

    Chondromyxoid fibroma is an uncommon benign cartilaginous tumor of the bone. It occurs most frequently in the metaphysis of long tubular bones, and an epiphyseal location is exceedingly rare. We present here an unusual case of a chondromyxoid fibroma that occurred in the epiphysis of the proximal tibia with an open growth plate. MR imaging findings of this tumor, which has, to the best of our knowledge, never been described in an epiphyseal location, makes the present case unique.

  19. A unique pattern of delayed enhancement of a large cardiac fibroma on magnetic resonance imaging.

    Science.gov (United States)

    El Yaman, Malek M; Vos, Jeffrey A; Gustafson, Robert A

    2015-06-01

    MRI is a valuable noninvasive tool that helps in predicting the type of cardiac tumors and guiding management decisions. Several reports have described the appearance of cardiac fibromas on MRI, which typically show hyperenhancement on myocardial delayed enhancement (MDE) imaging, with or without a dark core. This report demonstrates the unique appearance of a large solitary ventricular septal cardiac fibroma in a 5-month-old patient on MDE imaging, with two discrete dark cores, each surrounded by a hyperenhancing pseudocapsule.

  20. [Multiple cemento-ossifying fibromas of the jaw: a very rare diagnosis].

    Science.gov (United States)

    Stergiou, Georges C; Zwahlen, Roger A; Grätz, Klaus W

    2007-01-01

    The cemento-ossifying fibromas (COF) of the jaws are well circumscribed, generally slow-growing, benign lesions which enlarge in an expansive manner. On occasion, they may reach a large size and may result in considerable deformity. The histological pattern of these lesions varies with the stages. In most reported cases ossifying and cemento-ossifying fibromas occur as a solitary lesion. Multiple occurrence of such lesions is rare. The term"cemento-ossifying fibroma"is used to describe fibrous lesions containing calcifications with strong similarity between bone and cementum. Although WHO and some authors regard the cementifying fibroma (CF) as an odontogenic tumor and consider ossifying fibroma (OF) separately as non-odontogenic neoplasm, there is general agreement that CF and OF represent only histologic variants of the same lesion. The case of a 36-year old woman with multiple cemento-ossifying fibromas of the mandible and maxilla demonstrates the diagnostic procedures and a possible therapeutic strategy for this rare lesion.

  1. Nonossifying fibroma developed in metaphysis and epiphysis--a case report.

    Science.gov (United States)

    Noh, Jung Ho; Ryu, Kyung Nam; Bae, Ji Yoon; Roh, Young Hak; Choi, In Seok

    2013-04-01

    Nonossifying fibroma is developed in childhood and adolescence and is usually asymptomatic. It is typically arises in the metaphysis of long bone and migrates toward the diaphysis with growth. We present a very rare case of nonossifying fibroma involving metaphysis and epiphysis of the distal femur in a 20-year-old man. Nonossifying fibroma is a benign fibroblastic lesion, which is also termed benign cortical defect and fibroxanthoma. A nonossifying fibroma rarely causes problems and does not interfere with healing or growth. The lesions are usually asymptomatic. With growth and remodeling of the bone, the lesion typically disappears and is replaced with normal bone. However, the lesion may weaken the involved bone, causing fracture. The lesion typically arises in the metaphysis of long bones and may migrate toward the diaphysis with growth. There have never been reports of nonossifying fibroma involving epiphysis that we know of. We report a very rare case of nonossifying fibroma involving metaphysis and epiphysis in a young adult. Written, informed consent was obtained from the patient to publish this case report, including the images.

  2. The clinical and radiologic consideration of cementifying and ossifying fibroma of the jaws

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    Jo, Eun Young; Kim, Kee Deog; Park, Chang Seo [Dept. of Oral Radiology, College of Dentistry, Yensei University, Seoul (Korea, Republic of)

    1997-08-15

    The purpose of this study was to know the proper diagnosis and to establish the treatment plan of cementifying and ossifying fibroma in the jaws through the clinical, radiological, and histopathologic considerations. The authors compared and analyzed the clinicoradiologic features of the thirteen cases of cementifying and ossifying fibroma, diagnosed at the Dental college hospital in Yonsei university, Seoul, Korea, during the period from 1980 to 1995. The obtained results were as follows : 1. Cementifying and ossifying fibroma occurred in the mean age, 44 years, ranged from 29 to 65 years and the male to female ratio was approximately 1:5. 2. Swelling was the most common frequent presenting complaints. Other reported symptoms included pain, tooth mobility and symptom. 3. The frequency of the lesions was twelve cases in the mandible and one case in the maxilla. And eleven of thirteen cases were distributed on the premolar and molar region. 4. Radiologically, eight of thirteen cases were well defined lesions, five cases were relatively well defined lesions. And nine of thirteen cases were mixed lesions, three cases were radiopaque lesions, and only one case was purely radiolucent lesion. 5. Histologically, seven of thirteen cases were classified ossifying fibroma, four cases were cemento-ossifying fibroma, and two cases were cementifying fibroma.

  3. Incidence of Shope's rabbit fibroma in cottontails at the Patuxent Research Refuge

    Science.gov (United States)

    Herman, C.M.; Kilham, L.; Warbach, O.

    1956-01-01

    Between March, 1947, and December,1953, 359 cottontails were examined for evidence of fibromas at the Patuxent Research Refuge, Laurel, Md. No tumors were observed on the rabbits until December, 1950, when 3 of 16 shot animals had fibromas. Twelve rabbits of 70 examined in 1951, had tumors, and no tumors were found on 37 examined in 1952 and 29 examined in 1953. Neutralization tests, using Shope (OA) fibroma virus, were positive on sera from 6 of 36 rabbits trapped between July and December, 1951; one of two rabbits tested in 1952 showed evidence of antibodies; and 2 of 9 tested in 1953 were positive. Neither fibromas nor circulating antibodies were found in 70 cottontails trapped in January and February, 1953, in Rockville, Maryland and over 30 cottontails obtained from dealers in Kansas and Arkansas. No lesions developed on several species of mammals inoculated with a strain of the fibroma virus isolated from a wild cottontail captured on the Refuge. These findings were interpreted as indication of occurrence of an epizootic during the period December, 1950 through December, 1951. Although the local cottontail population showed a marked drop following this epizootic, available data were insufficient to determine whether or not fibroma virus was a contributing factor.

  4. Laparoscopic ovarian-sparing surgery for a young woman with an exophytic ovarian fibroma.

    Science.gov (United States)

    Hasegawa, Akiko; Koga, Kaori; Asada, Kayo; Wada-Hiraike, Osamu; Osuga, Yutaka; Kozuma, Shiro

    2013-12-01

    Ovarian fibroma can occur in young women of reproductive age. Despite its benign feature, most surgical removals are done in open surgery with oophorectomy. However, an ovarian-sparing tumor resection can be an option, especially for an exophytic type of fibroma, which accounts for more than half of ovarian fibromas. Here we report a case of exophytic ovarian fibroma in a young woman treated by laparoscopic ovarian-sparing surgery. A 27-year-old woman presented with a pelvic mass. Magnetic resonance imaging revealed an 11 cm × 8 cm solid mass connected to the normal-appearing left ovary by a pedicle-like structure. A clinical diagnosis of an exophytic ovarian fibroma was made, and laparoscopic ovarian-sparing surgery with an intraoperative pathological examination was planned. The tumor was resected by cutting the pedicle, morcellated in a pouch and removed. All procedures were performed laparoscopically and the affected ovary was completely preserved. Having confirmation of its benign characteristics by the intraoperative examination, no further excision was performed. The patient conceived 3 months after the surgery and no recurrence was reported. We propose that gynecologists should consider laparoscopic ovarian-sparing surgery for exophytic ovarian fibroma in women of reproductive age.

  5. Chondromyxoid fibroma of C1: first case report Fibroma condromixoide de C1: primer caso Fibroma condromixóide de C1: primeiro relato de caso

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    Ericson Sfreddo

    2012-01-01

    Full Text Available BACKGROUND: Chondromyxoid fibroma (CMF is a rare, benign primary bone tumor. The cervical spine is an uncommon site for this tumor, with only 10 reported cases to date and none involving the first cervical vertebra (C1. CASE REPORT: Female patient, 25-year-old monozygotic female twin, presented with cervical pain. Radiographic imaging demonstrated a contrast-enhanced, right-sided lytic lesion of the insufflated type in C1, with a punched-out appearance and extending to the anterior arch. A postero-lateral and a posterior approach were performed in two steps to resect the tumor followed by occipitocervical fixation. Pathology confirmed the diagnosis of CMF. At one year, the patient remains disease free with excellent spinal stability. CONCLUSION: Spinal surgeons may need to treat rare spinal tumors. Despite the proximity to neural and vascular structures, the goal of surgery is always a radical resection due to high recurrence rates.REVISIÓN: El fibroma condromixoide (FCM es un tumor óseo primario, benigno y raro. La columna cervical es un lugar raro de este tumor, con solamente 10 casos relatados, siendo que ninguno involucra a la primera vértebra cervical (C1. RELATO DEL CASO: Paciente del sexo femenino, 25 años, gemela monozigótica, presentando dolor cervical. La imagen radiográfica demostró una lesión contrastada, predominantemente en la masa lateral de C1 con extensión hacia el arco posterior y anterior. La resección del tumor se realizó en dos tiempos, inicialmente una aproximación posterolateral, seguida por la vía posterior. En esta última, se realizó una fijación occipitocervical. El análisis anatomopatológico fue compatible con FCM. Pasado un año de los procedimientos, la paciente permanecía sin enfermedad y con estabilidad cranio-cervical. CONCLUSIÓN: Especialistas de columna deben tener el conocimiento de que estos tumores raros pueden acometer a la columna vertebral y, a pesar de su proximidad con el tejido

  6. Calcifying odontogenic cyst with ameloblastic fibroma: report of three cases.

    Science.gov (United States)

    Lin, Cheng-Chung; Chen, Chung-Ho; Lin, Li-Min; Chen, Yuk-Kwan; Wright, John M; Kessler, Harvey P; Cheng, Yi-Shing Lisa; Ellis, Edward

    2004-10-01

    Although it is a rare event, odontogenic tumors such as ameloblastoma, ameloblastic fibroma (AF), ameloblastic fibro-odontoma, and odontoma have been reported associated with calcifying odontogenic cyst (COC). There are only four cases of COC with AF cited in the English literature. However, three of these four cases were either included in a review of a series of cases or reported as an abstract, and limited clinical and histological information was provided. We present three additional cases of COC with AF and discuss the management for this combined lesion. Because COC is known for its histologic diversity and variable clinical behavior, and the clinical significance of an association of COC with AF is still unknown, we think it is valuable to report COC with AF with detailed clinical and pathological documentation.

  7. Large cardiac fibroma and teratoma in children- case reports.

    Science.gov (United States)

    Jha, Neerod Kumar; Kiraly, Laszlo; Tamas, Csaba; Talo, Haitham; Khan, Mohammad Daud; El Badaoui, Hazem; Jain, Anurag; Hammad, Azzam

    2015-03-22

    Primary cardiac tumours in paediatric population are an unusual occurrence. Although, majority of such tumours are benign (90%), the frequency and type of cardiac tumours in this age group is different from the adult population. There are several consecutive series published in the last decade on cardiac neoplasms. Therefore, this is not only an effort to contribute to the existing literature for better understanding and management of similar patients but also to highlight the importance of early detection either by prenatal imaging or careful evaluation of differential diagnosis of common symptoms. We herein, describe two infants with large cardiac tumours (fibroma and teratoma) both arising from the interventricular septum and underwent surgical excision. A possible role of cardiac remodeling in myocardial tissue healing after extensive tissue resection in such patients is hypothesised through available experimental or limited clinical information.

  8. Cemento-ossifying fibroma of mandible mimicking complex composite odontome.

    Science.gov (United States)

    Dewan, Hitesh Sudarshan; Dewan, Sudarshan Kumar; Bahl, Sumit; Tushar Parekh, Parth

    2016-10-19

    Cemento-ossifying fibroma (COF) is a fibro-osseous lesion or non-odontogenic tumour that affects craniofacial bones. These lesions are included in the spectrum of fibro-osseous lesions arising from periodontal ligament cells, which can deposit combination of cementum and bone surrounded by fibrous tissue. It clinically, macroscopically and radiologically resembles complex composite odontome and can be differentiated only on the basis of histopathology. They usually occur solitarily as a painless and expansile spherical or ovoid jawbone mass that may displace the roots of adjacent teeth. They predominantly occur in females in third and fourth decades of life. We present a case report of a 20-year-old man, with a mildly painful swelling in the mandible which was successfully treated with enucleation and diagnosed as COF. Its resemblance to complex composite odontome and unique surgical approach are highlighted in this paper. 2016 BMJ Publishing Group Ltd.

  9. Giant cemento-ossifying fibroma of the maxilla.

    Science.gov (United States)

    Unal, Adnan; Yurtsever Kum, Nurcan; Kum, Rauf Oguzhan; Erdogan, Aysun; Ciliz, Deniz Sozmen; Guresci, Servet; Ozcan, Muge

    2015-11-14

    Fibro-osseous lesions of the skull and facial bones are benign tumors, but they can be mistaken for malignant tumors due to their clinically aggressive behavior. Cemento-ossifying fibroma (COF) is a benign fibro-osseous lesion characterized by slow growth and fibrous and calcified tissue content. COFs are locally destructive lesions causing deformities in the bones. The recurrence risk is high if they are not completely removed. In this case report we describe a giant COF mimicking chondrosarcoma in the oral cavity of a 55-year-old woman causing significant facial deformity and feeding problems. Giant COF occurs rarely in the jaws and given that this lesion has similar imaging and clinical features to several other tumors, the diagnosis is always a challenge for clinicians, radiologists and pathologists.

  10. Central cemento-ossifying fibroma of posterior maxilla

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    Uday Shankar Yaga

    2015-01-01

    Full Text Available Cemento-ossifying fibromas (COFs are relatively rare, benign lesions affecting the jaws and other craniofacial bones and are included in the group of mesodermal odontogenic tumors by Gorlin. They have a predilection for females between the third and fourth decades of life, and about 60% of the lesions are seen most often in the mandibular arch, predominantly occurring in the premolar/molar region of the mandible. This report describes a case of central COF in a 49-year-old male involving the maxillary posterior region. The current case is reported because of the rarity of such lesions and the paucity of information concerning them in the dental literature. We believe that this case illustrates many of the clinical, radiographic, and histologic features associated with cemento-ossifying tumors.

  11. CT and MRI of congenital sinonasal ossifying fibroma

    Energy Technology Data Exchange (ETDEWEB)

    Engelbrecht, V. [Inst. of Diagnostic Radiology, Heinrich Heine Univ. Duesseldorf (Germany); Preis, S.; Hassler, W. [Dept. of Pediatrics, Heinrich Heine Univ. Duesseldorf (Germany); Lenard, H.G. [Dept. of Neurosurgery, Municipal Hospitals, Duisburg (Germany)

    1999-07-01

    We report a 9-year-old boy with a sinonasal ossifying fibroma, probably congential, with atypical findings on CT and MRI. CT revealed a soft-tissue density mass in the sphenoethmoidal sinuses, nasal cavity and right maxillary sinus with a few foci of calcification and with remodelling and destruction of the adjacent facial bones. MRI showed high signal on T2- and intermediate signal on T1-weighted images. A thin, partly enhancing outer shell and some nonenhancing septa were visible on contrast-enhanced images. MRI also showed the tumour to extend into the anterior cranial fossa. Subtotal removal was performed. We compare our findings with reports in the literature and discuss the differences from fibrous dysplasia. (orig.)

  12. Ameloblastic fibroma in an alpine chamois (Rupicapra rupicapra).

    Science.gov (United States)

    Scaglione, F E; Iussich, S; Grande, D; Carpignano, M; Chiappino, L; Sereno, A; Ferroglio, E; Bollo, E

    2015-04-01

    Spontaneous odontogenic tumors are neoplasms characterized by a mixed odontogenic ectomesenchymal and odontogenic epithelial origin; they are rare in both humans and animals. A 3-year-old male Alpine Chamois (Rupicapra rupicapra) was found dead in north-west Italy, and was referred for the necropsy to the Department of Veterinary Sciences of the University of Turin (Italy). At the external examination a 10 × 8 cm, exophytic, red-pink, smooth, firm and ulcerated mass was observed on the inferior lip. Histologically the tumor was characterized by spindle shaped cells arranged in bundles in an abundant hyaline matrix. Multifocal and rare chords of odontogenic epithelium mixed with rare melanocytes that penetrate the neoplasia were visible. Immunohistochemistry showed a clear cytokeratin positivity of epithelial clusters. Macroscopical, histological and immunohistochemical findings were consistent with a diagnosis of locally infiltrative ameloblastic fibroma. To our best knowledge, this is the first report of this tumor in a wild ungulate and in Alpine Chamois.

  13. Chondromyxoid fibroma of the acromium with soft tissue extension

    Energy Technology Data Exchange (ETDEWEB)

    Macdonald, D. [Departments of Anatomic and Clinical Pathology, Sunnybrook and Women' s College Health Sciences Centre, Orthopedic and Arthritic Institute, Toronto, Ontario (Canada); University of Toronto, Toronto, Ontario (Canada); Fornasier, V. [Department of Anatomical Pathology and Cytology, St. Michael' s Hospital, Wellesley-Central Site, Toronto, Ontario (Canada); Holtby, R. [Department of Surgery, Sunnybrook and Women' s College Health Sciences Centre, Orthopedic and Arthritic Institute, Toronto, Ontario (Canada)

    2000-03-30

    Chondromyxoid fibroma is an unusual, benign tumor of cartilaginous origin and represents less than 1% of all primary bone tumors. It usually involves the long bones around the knee joint or the flat bones of the pelvis or ribs. Soft tissue extension is also thought to be rare in these lesions. They are usually eccentrically located in the metaphyses of the long bones and centrally in the flat bones. The radiographic appearances are characteristically those of a single, lytic lesion with lobulated margins, septations, cortical expansion and a sclerotic rim. Histologically, they display a lobulated pattern with spindle-shaped cells lying within a myxoid matrix with areas of hyaline cartilage. The differential diagnosis includes giant cell tumor, chondroblastoma or enchondroma as well as chondrosarcoma. The rarity of these lesions may render the diagnosis difficult to make, especially when the lesion involves an unusual site such as the acromium. (orig.)

  14. Diode laser for excisional biopsy of peripheral ossifying fibroma

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    Kirti Chawla

    2014-01-01

    Full Text Available Peripheral Ossifying Fibroma is one of the commonest occurring reactive lesions on gingiva. It is associated with local irritational factors and often interferes with speech, mastication and maintenance of oral hygiene, in addition to being aesthetically unpleasant. It is usually treated with surgical excision using scalpel and removal of irritational factors, often resulting in mucogingival defect. Other modalities such as radiosurgery and electrocautery have also been used for its management, but they cause changes in microarchitecture of biopsy specimen, altering the histologic picture for true diagnosis. We are presenting a case of excisional biopsy of this lesion in an adult female using a diode laser with excellent post-operative results, without affecting microarchitecture of biopsy specimen. The patient is being followed for last 1 year and no sign of recurrence has been found. A diode laser may offer a good alternative modality for management of such cases.

  15. Recurrent ameloblastic fibroma: report of a rare case.

    Science.gov (United States)

    Kulkarni, Ravikumar S; Sarkar, Amitabh; Goyal, Sandeep

    2013-01-01

    Ameloblastic fibroma (AF) is an uncommon mixed neoplasm of odontogenic origin frequently seen in the second decade of life. It mainly presents as an intrabony lesion but can even occur peripherally. Histologically, our case showed hypercellular areas, an uncommon feature seen in typical AF. Whether this benign lesion is treated by mode of enucleation and curettage or by extensive surgery is still a topic of debate. An extensive surgical treatment is suggested as the initial approach due to its high recurrence rate (18%) and the greater chances of recurrent AFs transforming into ameloblastic fibrosarcoma (45%), together with a long-term followup. We report a case of recurrent AF with hypercellular ectomesenchyme which developed a year after its conservative removal. We conclude that in recurrent AF sufficient sections of the pathological specimen are to be taken to rule out any malignant changes that might have begun in focal areas.

  16. Recurrent Ameloblastic Fibroma: Report of a Rare Case

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    Ravikumar S. Kulkarni

    2013-01-01

    Full Text Available Ameloblastic fibroma (AF is an uncommon mixed neoplasm of odontogenic origin frequently seen in the second decade of life. It mainly presents as an intrabony lesion but can even occur peripherally. Histologically, our case showed hypercellular areas, an uncommon feature seen in typical AF. Whether this benign lesion is treated by mode of enucleation and curettage or by extensive surgery is still a topic of debate. An extensive surgical treatment is suggested as the initial approach due to its high recurrence rate (18% and the greater chances of recurrent AFs transforming into ameloblastic fibrosarcoma (45%, together with a long-term followup. We report a case of recurrent AF with hypercellular ectomesenchyme which developed a year after its conservative removal. We conclude that in recurrent AF sufficient sections of the pathological specimen are to be taken to rule out any malignant changes that might have begun in focal areas.

  17. Ameloblastic fibroma of the mandible. Report of two cases.

    Science.gov (United States)

    Martín-Granizo López, Rafael; Ortega, Luis; González Corchón, Ma Aránzazu; Berguer Sández, Alberto

    2003-01-01

    The ameloblastic fibroma (AF)-ameloblastic fibro-odontoma (AFO), is an uncommon benign mixed odontogenic tumor (epithelial and mesenchymal), that represents the 2% of all odontogenic tumors. It usually appears in the mandible and in the posterior segments of young patients without gender predilection, and sometimes is associated with an impacted tooth. The classification of the WHO includes it in the subtype of odontogenic tumors with a defined histologic features. The AF and the AFO are considered as an unique entity as they are variations of the same tumor, only distinct for the presence of an odontoma in the case of the AFO. Surgical conservative treatment with excision followed by curettage seems to be the most appropriate therapeutic option. The objective of this paper is to report two cases of this tumor, to make a brief review of the literature and its differential diagnosis, to analyse its clinical and histologic features and the therapeutic option.

  18. Ameloblastic fibroma or fibrosarcoma: A dilemma of oral surgeon.

    Science.gov (United States)

    Verma, Nitin; Neha

    2016-01-01

    Ameloblastic fibroma (AF) is an uncommon true mixed odontogenic tumor, with a relative frequency between 1.5% and 4.5% of all odontogenic tumors. It may behave either as a true neoplasm or as a hamartomatous proliferation of odontogenic epithelium of the enamel organ and odontogenic mesenchyme of the primitive dental pulp. Frequently diagnosed between the first and second decades of life with 75% of cases was diagnosed before the age of 20 and present with a well-defined unilocular or multilocular radiolucencies. A conservative approach, enucleation with curettage, and long-term follow-up are absolutely necessary for any recurrence or change to fibrosarcoma. We report a case of AF in a 10-year-old male patient who presented with a chief complaint of swelling in the right mandibular posterior region. Enucleation and curettage were done under general anesthesia, followed by immunohistochemical markers (Ki-67, Mib-1) to assess the sarcomatous changes and aggressiveness of the tumor.

  19. Fibroma osificante periférico: caso clínico

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    Zoila Beatriz Carbonell Muñoz

    2013-10-01

    Full Text Available ResumenEl fibroma osificante periférico es una lesión reactiva, se considera que se origina de las células del ligamento periodontal; son lesiones benignas de tejido conectivo con focos de calcificación generalmente asintomáticas. En este artículo se presenta un caso de fibroma osificante periférico, permitiendo destacar la importancia clínica de este tipo de patología poco frecuente y con una actualizada revisión de literatura se busca afianzar conocimientos que conlleven a un correcto diagnóstico y adecuado manejo terapéutico para la resolución de la patología. El caso clínico trata de una paciente de 30 años de edad que acude a consulta por presentar lesión tumoral a nivel del cuerpo mandibular izquierdo. Previa valoración clínica y radiográfica, se sometió a la paciente al retiro quirúrgico de la lesión, el examen histopatológico reportó el diagnóstico de fibroma osificante periférico. (DUAZARY 2010, 223 - 227AbstractThe peripheral ossifying fibroma (POF is a reactive lesion who originates in the cells of the periodontal ligament. They are benign tumors of connective tissue usually asymptomatic and they are located in both jaws with greater predilection in the upper jaw, in the region of the interdental papilla and adjacent teeth. It´s presented a case of a 30 years old patient who was attended for an injury tumor located at the left of the mandibular body. After clinical assessment the patient was submitted to surgical removal of the lesion, the review reported histopathologic diagnosis of peripheral ossifying fibroma.Keywords: peripheral ossifying fibroma; Fibroma with Calcification; Calcifying Fibroblastic Granuloma.

  20. Imaging study of ossifying fibroma with associated aneurysmal bone cyst in the paranasal sinus

    Energy Technology Data Exchange (ETDEWEB)

    Yang, B.T., E-mail: cjr.yangbentao@vip.163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing 100730 (China); Wang, Y.Z., E-mail: yzwang1981@163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing 100730 (China); Wang, X.Y., E-mail: juanjuan0824@163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing 100730 (China); Wang, Z.C., E-mail: cjr.wzhch@vip.163.com [Department of Radiology, Beijing Tongren Hospital, Capital Medical University, No. 1, Dongjiaominxiang, Dongcheng District, Beijing 100730 (China)

    2012-11-15

    Objective: To determine the CT and MR imaging features of ossifying fibroma with aneurysmal bone cyst of the paranasal sinus. Materials and methods: We retrospectively reviewed 15 patients with histopathology-proven ossifying fibromas with aneurysmal bone cysts in the paranasal sinus. All 15 patients underwent CT and MR imaging. The following imaging features were reviewed: location, shape, margin, CT findings, and MR imaging appearances and time-intensity curve of dynamic contrast-enhanced MR imaging. Results: Ossifying fibromas occurred in the maxillary sinus in one patient, sphenoid sinus in 2, frontal sinus in 3, frontoethmoid sinuses in 3, and ethmoid sinus in 6 patients. Ossifying fibromas showed an elliptic-shape and aneurysmal bone cysts revealed a multicystic appearance, with well-demarcated margins. On unenhanced CT, ossifying fibromas appeared isodense to gray matter with scattered calcifications in nine, ground-glass appearance in 6 patients and aneurysmal bone cysts showed mixed density. Ossifying fibromas appeared isointense to gray matter in 12 and slightly hypointense in three patients on T1-weighted images, and isointense in 4 and hypointense in eleven patients on T2-weighted images, with moderate or marked enhancement after administration of contrast material. The time-intensity curves of eight ossifying fibromas exhibited a rapidly enhancing and rapid washout pattern. The intracystic components of aneurysmal bone cysts showed heterogeneous signal intensity on MR images, with fluid-fluid levels identified clearly by T2-weighted images, without enhancement. The periphery and septa of aneurysmal bone cysts appeared isointense on MR images, with marked enhancement. Conclusions: Fluid-fluid levels within an elliptic-shape mass with scattered calcifications or ground-glass appearance is highly suggestive of this complicated entity in the paranasal sinus.

  1. Aberrations of 6q13 mapped to the COL12A1 locus in chondromyxoid fibroma.

    Science.gov (United States)

    Yasuda, Taketoshi; Nishio, Jun; Sumegi, Janos; Kapels, Kayla M; Althof, Pamela A; Sawyer, Jeffrey R; Reith, John D; Bridge, Julia A

    2009-11-01

    Chondromyxoid fibroma, a rare benign bone tumor, may be mistaken for chondrosarcoma. Although cytogenetic studies of chondromyxoid fibroma are few, rearrangements of the long arm of chromosome 6, frequently expressed as an inv(6)(p25q13), are prominent. In this study, conventional cytogenetic analysis of 16 chondromyxoid fibroma samples from 14 patients revealed rearrangements of chromosome 6 in 10 of 11 clonally abnormal specimens. In addition to 6q13 rearrangements, recurrent 6p25 and 6q25 anomalies were detected. Notably, an identical t(6;9)(q25;q22) translocation was identified in two cases, suggesting that it represents a distinct translocation of chondromyxoid fibroma. In an effort to further define the aberrant 6q13 breakpoint and identify the molecular consequences, a fluorescence in situ hybridization (FISH)-based positional cloning strategy on chondromyxoid fibroma abnormal metaphase and interphase cells using a series of bacterial and plasmid artificial chromosome (BAC/PAC) probe combinations spanning a 6.1 Mb region was employed. The breakpoint on 6q13 was located within the COL12A1 gene, a collagen gene purportedly involved in another benign bone tumor, subungual exostosis. The findings of this study expand our knowledge of chromosomal alterations in chondromyxoid fibroma, identify COL12A1 as the likely gene candidate within the recurrent 6q13 breakpoint, and provide an alternative approach for detecting 6q13 anomalies in nondividing cells of chondromyxoid fibroma. The latter could potentially be utilized as an adjunct in diagnostically challenging cases.

  2. Fibroma ameloblástico versus quiste folicular hiperplásico Ameloblastic fibroma versus hyperplastic follicular cyst

    Directory of Open Access Journals (Sweden)

    J. Azúa-Romeo

    2004-06-01

    Full Text Available Resumen: El fibroma ameloblástico (FA es un tumor odontogénico mixto, compuesto por tejido mesenquimal y epitelio odontogénico, representando el 2% de los tumores odontogénicos, mientras que el quiste dentígero o folicular (QF, el segundo quiste odontogénico en frecuencia, está compuesto exclusivamente por tejido conjuntivo laxo (mesénquima, si bien, el saco fibroso puede contener restos de epitelio odontogénico incluidos, dando lugar a una imagen histológica muy similar. La importancia de esta diferenciación radica en el tratamiento, que es ligeramente más agresivo en el FA y en el comportamiento biológico, ya que el FA puede derivar en un sarcoma ameloblástico, y el QF puede evolucionar hacia ameloblastoma y más raramente carcinoma mucoepidermoide.Abstract: Ameloblastic fibroma (AF is a mixed odontogenic tumor composed of mesenchymal tissue and odontogenic epithelium, accounting for 2% of all odontogenic tumors, while dentigerous or follicular cyst (FQ, second odontogenic cyst in frequency, is formed exclusivelly by soft conective tissue (mesenchyme. Nevertheless, hiperplastic fibrous sac may contain rests of odontogenic epithelium, showing a similar histologic pattern. The importance of an adequate differentiation lies in the treatment, which is slightly aggresive for AF, and regarding the biological behaviour of both lesions, since AF might become in an ameloblastic sarcoma, while over an FQ could develope an ameloblastoma or even a mucoepidermoid carcinoma.

  3. Phenotypic diversity in chondromyxoid fibroma reveals differentiation pattern of tumor mimicking fetal cartilage canals development: an immunohistochemical study.

    Science.gov (United States)

    Zustin, Jozef; Akpalo, Hana; Gambarotti, Marco; Priemel, Matthias; Rueger, Johannes M; Luebke, Andreas M; Reske, Dennis; Lange, Claudia; Pueschel, Klaus; Lohmann, Christoph; Rüther, Wolfgang; Amling, Michael; Alberghini, Marco

    2010-09-01

    Chondromyxoid fibroma represents a rare benign cartilaginous tumor of young patients occurring in a subcortical metaphyseal location. The histogenesis of chondromyxoid fibroma has not yet been postulated, even though the conventional histology and recent immunohistochemical studies on phenotype of the mesenchymal cells and extracellular matrix components suggested its origin in immature cartilage. Therefore, we wished to compare the morphological pattern of immature cartilage tissue with chondromyxoid fibroma to investigate a possible developmental counterpart of chondromyxoid fibroma. Archival paraffin-embedded tissues from 4 fetal femora and 10 cases of chondromyxoid fibroma were analyzed simultaneously using histochemistry (safranin O) and established immunohistochemical antibodies (CD34, CD163, and smooth muscle actin). Vascularized cartilage canals growing into the fetal cartilage from the perichondrium displayed characteristic glomeruloid structures with central arterioles within the immature mesenchymal stroma and numerous superficial sinusoidal blood vessels accompanied by macrophage infiltration. Similarly, each case of chondromyxoid fibroma demonstrated admixture of two characteristic components: immature fibrous tissue of vascularized stroma with accumulation of macrophages in areas of superficial sinusoidal proliferation, and variable amounts of lobulated chondroid tissue. Based on the observed substantial morphological similarity between the cartilage canals and chondromyxoid fibroma, we suggest that the chondromyxoid fibroma represents a neoplasm originating from or mimicking the fetal cartilage canals within the immature cartilage.

  4. Histochemical and immunohistochemical differences between solitary oral fibroma and fibrous papule of the face*

    Science.gov (United States)

    Henriques, Águida Cristina Gomes; Freitas, Roseana de Almeida; Pires, Bruno Cunha; Gurgel, Clarissa Araújo; dos Santos, Jean Nunes

    2016-01-01

    Background The morphological similarities between fibrous papules of the face and multiple sporadic oral fibromas were mentioned long ago and a relationship between them has been reported in the literature. Objective The aim of this study was to evaluate the participation of mast cells, elastin and collagen in a series of oral fibromas and fibrous papules of the face in order to better understand the possible role of these factors in fibrosis and the formation of these lesions. Methods Thirty cases of oral fibroma involving the buccal mucosa and 30 cases of fibrous papules of the face were selected. Tissue samples were submitted to picrosirius red staining and immunohistochemistry using anti-elastin and anti-tryptase antibodies. Results The percentage of tryptase-positive mast cells and expression of elastin were higher in cases of fibrous papules of the face (p < 0.05). In contrast, a higher intensity of collagen deposition was observed in oral fibromas. The results showed mast cell accumulation and higher elastin synthesis in fibrous papules of the face, and mast cell accumulation with higher collagen fiber synthesis in oral fibromas. Conclusion These findings support the hypothesis that mast cells influence the development and growth of these lesions through different mechanisms. PMID:27828630

  5. Surgical resection of a huge cemento-ossifying fibroma in skull base by intraoral approach.

    Science.gov (United States)

    Cheng, Xiao-Bing; Li, Yun-Peng; Lei, De-Lin; Li, Xiao-Dong; Tian, Lei

    2011-03-01

    Cemento-ossifying fibroma, also known as ossifying fibroma, usually occurs in the mandible and less commonly in the maxilla. The huge example in the skull base is even rare. We present a case of a huge cemento-ossifying fibroma arising below the skull base of a 30-year-old woman patient. Radiologic investigations showed a giant, lobulated, heterogeneous calcified hard tissue mass, which is well circumscribed and is a mixture of radiolucent and radiopaque, situated at the rear of the right maxilla to the middle skull base. The tumor expands into the right maxillary sinus and the orbital cavity, fusing with the right maxilla at the maxillary tuberosity and blocking the bilateral choanas, which caused marked proptosis and blurred vision. The tumor was resected successfully by intraoral approach, and pathologic examination confirmed the lesion to be a cemento-ossifying fibroma. This case demonstrates that cemento-ossifying fibroma in the maxilla, not like in the mandible, may appear more aggressive because the extensive growth is unimpeded by anatomic obstacles and that the intraoral approach can be used to excise the tumor in the skull base.

  6. Beta-catenin mutations do not contribute to cardiac fibroma pathogenesis.

    Science.gov (United States)

    Miller, Dylan V; Wang, Huamin; Wang, Hua; Fealey, Michael E; Tazelaar, Henry D

    2008-01-01

    Cardiac fibromas are the 2nd most common benign cardiac tumor occurring in children and bear a striking morphologic resemblance to soft tissue or desmoid fibromatosis. Since activating mutations in beta-catenin are common in desmoid fibromatosis as well as other spindle cell proliferations, the aim of our study was to determine if such mutations could be identified in cardiac fibroma. Nine cardiac fibromas from patients with surgical resection were examined for beta-catenin mutations by immunoperoxidase staining for beta-catenin protein and DNA sequencing of a region in exon 3 of the beta-catenin gene, where relatively conserved mutations have been described in desmoid fibromatosis. The mean age of the patients was 7.6 years (range: 10 weeks to 27 years), and 6 of the patients were male. No nuclear staining for beta-catenin was seen in the fibroma cells by immunoperoxidase methods. The beta-catenin exon 3 sequence data showed no mutations in any of the 9 tumors. We conclude that despite their morphologic similarity, cardiac fibroma and desmoid fibromatosis do not share this common molecular pathway of neoplastic growth.

  7. Cosmology With Extra Dimensions

    CERN Document Server

    Martín, J

    2005-01-01

    We review several properties of models that include extra dimensions, focusing on aspects related to cosmology and particle physics phenomenology. The properties of effective four dimensional inflationary geometry are studied in two distinct frameworks: (i) in Kaluza- Klein (KK) compactifications and (ii) in braneworld scenarios. From numerical simulations we find that inflationary braneworlds are unstable if the scale of inflation is too large in comparison with the stabilization scale of the interbrane distance. The analysis of perturbations confirms the existence of a tachyon associated with the volume modulus of the extra dimensions both in braneworlds and KK compactifications. With the numerical program BRANECODE non- perturbative properties of braneworlds are studied. We fully understand the non-perturbative consequences of this instability. Generic attractors are (i) an increase of the interbrane distance and the formation of a naked singularity, (ii) the brane colli...

  8. SCONUL Research Extra

    OpenAIRE

    John Hall

    2006-01-01

    SCONUL Research Extra is a cooperative access and borrowing scheme for staff and research students in UK and Irish higher education institutions. Under the terms of the scheme, eligible researchers may visit any participating library and register as an external borrower. The scheme is run on behalf of SCONUL, the Society of College, National and University Libraries which represents the directors of the library and information services in all the universities of the United Kingdom and Ireland...

  9. Giant Cell Fibroma of the Buccal Mucosa with Laser Excision: Report of Unusual Case

    Science.gov (United States)

    Bagheri, Fatemeh; Rahmani, Somayyeh; Azimi, Somayyeh; Bigom Taheri, Jamileh

    2015-01-01

    Giant Cell Fibroma (GCF) was described as a new entity of fibrous hyperplastic soft tissue. It seems that stimulus from an unexplained origin can have a role in its etiology. Histopathologically GCF is consisted of multinucleated fibroblasts that have oval shape nuclei within the eosinophilic cytoplasm. Surgical excision is the treatment of choice and recurrence is very rare. Here we report a case of relatively large GCF in a 54-year-old man. Gingiva is the common location of GCF. As in our case, it may be mistaken as irritation fibroma especially if it is on the buccal mucosa, the most common location for fibroma. Correct diagnosis is based on biopsy and clinical examination to see surface texture roughness. To minimize bleeding because of its large size an excisional biopsy with Diod laser was performed under local anesthesia for this patient. PMID:26351504

  10. Chondromyxoid fibroma of the calcaneus: two case reports and literature review.

    Science.gov (United States)

    Roberts, Eric J; Meier, Molly J; Hild, Gina; Masadeh, Suhail; Hardy, Mark; Bakotic, Bradley W

    2013-01-01

    Chondromyxoid fibroma occurs primarily in the long tubular bones of the lower extremity, with the foot representing the second most frequent location after the knee. This benign cartilaginous tumor of bone is currently the rarest reported neoplasm of cartilaginous origin. This mass can mimic other benign and malignant bone tumors owing to its variable histologic features. We report 2 cases of chondromyxoid fibroma of the calcaneus with varying presentations. Initially, advanced imaging studies pointed to a diagnosis of a unicameral bone cyst. Pathologic examination is difficult but can be used to differentiate this lesion from more serious conditions. A quick and accurate diagnosis of chondromyxoid fibroma can prevent unnecessary treatment that could be harmful to the patient.

  11. Fibroma of the tendon sheath of the long head of the biceps tendon.

    Science.gov (United States)

    De Maeseneer, Michel; Van Isacker, Tom; Lenchik, Leon; Van Caillie, Marie-Astrid; Shahabpour, Maryam

    2014-03-01

    Fibroma of the tendon sheath is a benign tumor that is less common than giant cell tumor of the tendon sheath. Both tumors may present as a painless, slowly enlarging mass. Radiological findings may be similar for both tumors. Histologically, fibroma of the tendon sheath lacks the hemosiderin-laden macrophages that are typical for giant cell tumor of the tendon sheath. We report on a 49-year-old woman with fibroma of the tendon sheath of the long head of the biceps tendon. In our case, on MR images, we observed band-like hypointense areas centrally in the tumor, mild patchy contrast enhancement, and most importantly, no decrease of signal intensity on gradient echo images. These characteristics reflected histological findings.

  12. Fibroma of the tendon sheath of the long head of the biceps tendon

    Energy Technology Data Exchange (ETDEWEB)

    Maeseneer, Michel de; Shahabpour, Maryam [Universitair Ziekenhuis Brussel, Department of Radiology, Brussels (Belgium); Isacker, Tom van [Sint-Lucas Hospital, Department of Orthopedic Surgery, Brugge (Belgium); Lenchik, Leon [Wake Forest School of Medicine, Department of Radiology, Winston Salem, NC (United States); Caillie, Marie-Astrid van [Sint-Lucas Hospital, Department of Pathology, Brugge (Belgium)

    2014-03-15

    Fibroma of the tendon sheath is a benign tumor that is less common than giant cell tumor of the tendon sheath. Both tumors may present as a painless, slowly enlarging mass. Radiological findings may be similar for both tumors. Histologically, fibroma of the tendon sheath lacks the hemosiderin-laden macrophages that are typical for giant cell tumor of the tendon sheath. We report on a 49-year-old woman with fibroma of the tendon sheath of the long head of the biceps tendon. In our case, on MR images, we observed band-like hypointense areas centrally in the tumor, mild patchy contrast enhancement, and most importantly, no decrease of signal intensity on gradient echo images. These characteristics reflected histological findings. (orig.)

  13. Pathological fracture in non-ossifying fibroma with histological features simulating aneurysmal bone cyst

    Energy Technology Data Exchange (ETDEWEB)

    Hoeffel, C.; Mainard, L.; Hoeffel, J.C. [Dept. of Radiology, Hopital Jeanne d`Arc, Toul (France); Panuel, M. [Dept. of Radiology, Hopital Nord, Marseille (France); Plenat, F. [Dept. of Pathology, Hopital de Brabois Adultes, Vandoeuvre (France)

    1999-05-01

    A 12-year-old-girl presented with a fracture of an osteolytic lesion of the distal radius. A 7-year-old girl presented with a fracture of an osteolytic lesion of the femoral shaft. In both cases it was a non-ossifying fibroma with fracture misdiagnosed at pathology as aneurysmal bone cyst. Fractures through non-ossifying fibromas may alter the histological pattern of the initial lesion in two ways: firstly, by the presence of blood pigments due to the fracture, and secondly, by formation of new bone. Radiological-pathological correlation is essential to avoid histological errors after pathological fracture in a non-ossifying fibroma. (orig.) With 4 figs., 6 refs.

  14. Volatile organic metabolites identify patients with breast cancer, cyclomastopathy, and mammary gland fibroma.

    Science.gov (United States)

    Wang, Changsong; Sun, Bo; Guo, Lei; Wang, Xiaoyang; Ke, Chaofu; Liu, Shanshan; Zhao, Wei; Luo, Suqi; Guo, Zhigang; Zhang, Yang; Xu, Guowang; Li, Enyou

    2014-06-20

    The association between cancer and volatile organic metabolites in exhaled breaths has attracted increasing attention from researchers. The present study reports on a systematic study of gas profiles of metabolites in human exhaled breath by pattern recognition methods. Exhaled breath was collected from 85 patients with histologically confirmed breast disease (including 39 individuals with infiltrating ductal carcinoma, 25 individuals with cyclomastopathy and from 21 individuals with mammary gland fibroma) and 45 healthy volunteers. Principal component analysis and partial least squares discriminant analysis were used to process the final data. The volatile organic metabolites exhibited significant differences between breast cancer and normal controls, breast cancer and cyclomastopathy, and breast cancer and mammary gland fibroma; 21, 6, and 8 characteristic metabolites played decisive roles in sample classification, respectively (P fibroma patients, and patients with cyclomastopathy (P < 0.05). The identified three volatile organic metabolites associated with breast cancer may serve as novel diagnostic biomarkers.

  15. Cellular Fibroma of the Ovary with Multiloculated Macroscopic Characteristics: Case Report

    Directory of Open Access Journals (Sweden)

    Sheila Jorge Adad

    2012-01-01

    Full Text Available Ovarian fibroma is the commonest benign tumor of the ovarian stroma. The cellular subtype accounts for around 10% of ovarian fibromatous tumors. The cellular fibroma is a tumor of uncertain malignant potential that may recur or be associated with peritoneal implants. Usually these are solid tumors, sometimes with small areas of cystic degeneration. This case is reported to highlight an unusual feature for an ovarian fibroma: the tumor was predominantly cystic with a small solid part; the multiple cavities contents consisted of viscous liquid that solidified under room temperature. The multiloculated cysts, the mucinous contents, and the solid areas simulated a borderline mucinous ovarian tumor on both CT scan and gross pathologic examination.

  16. Recurrent angio-fibroma of breast masquerading as phyllodes tumor.

    Science.gov (United States)

    Chaurasia, Jai K; Alam, Feroz; Shadan, Mariam; Naim, Mohammed

    2015-01-01

    A young Indian female presented with a recurring tumor in the right breast masquerading as phyllodes tumor. Patient had history of five times excision and recurrences of the tumor, diagnosed as fibrous phyllodes of the breast. Presently, a well-circumscribed tumor of about 10 cm size, comprising of benign fibrous-angiomatous tissue with evidence of foci of pyogenic vasculitis was observed. Immuno-histochemical markers for the myo-epithelial and epithelial elements excluded the possibility of fibrous phyllodes, inflammatory myofibroblastic tumor, desmoid fibromatosis, and metaplastic carcinoma. The present findings were diagnostic of an inflammatory angio-fibroma of the right breast, not reported in the earlier literature. The observations indicated that the female breast may be susceptible to spontaneous productive and common-antibiotic-resistant focal septic vascular inflammation giving rise to angio-fibromatous proliferation producing a well-defined tumor mass in the breast, distinguishable from the other breast lesions by the connective tissue stains and immuno-histochemical markers.

  17. Ameloblastic fibroma and related lesions: current pathologic concept.

    Science.gov (United States)

    Takeda, Y

    1999-11-01

    Ameloblastic fibroma (AF) is a true mixed tumor, in which the epithelial and the ectomesenchymal elements are neoplastic. There are two rare variants of AF; granular cell AF and peripheral AF. Ameloblastic fibrosarcoma is a rare tumor, and is regarded as the malignant counterpart of the benign AF. Recent immunohistochemical study using MIB-1 shows labelling indices in the mesenchymal component of the recurrent AF and ameloblastic fibrosarcoma are quite high, in contrast with the conventional AF. Ameloblastic fibrodentinoma is a histologic variant of AF in which dentin or dentinoid tissue has formed, but there is no eveidence that ameloblastic fibrodentinoma exhibit a different biologic behavior than ordinary AF. Ameloblastic fibro-odontoma is a lesion similar to AF, but also showing inductive changes that lead to the formation of both dentin and enamel. Some lesions diagnosed as ameloblastic fibro-odontoma are probably developing odontoma, but the others should not be considered as hamartomatous in nature, since there are rare cases of ameloblastic fibro-odontoma showing true neoplastic behavior, and since the existence of malignant variant is evident. In revised WHO's classification of odontogenic tumors, the terms "ameloblastic fibrodentinoma" and "dentinoma" are used synonymously, however, there are histologic difference between several cases reported previously as "dentinoma" and ameloblastic fibrodentinoma.

  18. Ameloblastic fibroma and ameloblastic fibrosarcoma: A systematic review.

    Science.gov (United States)

    Chrcanovic, Bruno Ramos; Brennan, Peter A; Rahimi, Siavash; Gomez, Ricardo Santiago

    2017-08-04

    To integrate the available data published to date on ameloblastic fibromas (AF) and ameloblastic fibrosarcomas (AFS) into a comprehensive analysis of their clinical/radiological features. An electronic search was undertaken in July 2017. Eligibility criteria included publications having enough clinical, radiological and histological information to confirm a definite diagnosis. A total of 244 publications (279 central AF tumours, 10 peripheral AF, 103 AFS) were included. AF and AFS differed significantly with regard to the occurrence of patients' mean age, bone expansion, cortical bone perforation and lesion size. Recurrence rates were as follows: central AF (19.2%), peripheral AF (12.5%), AFS (all lesions, 35%), primary (de novo) AFS (28.8%) and secondary AFS (occurring after an AF, 50%). Larger lesions and older patients were more often treated by surgical resections for central AF. Segmental resection resulted in the lowest rate of recurrence for most of the lesion types. AFS treated by segmental resection had a 70.5% lower probability to recur (OR 0.295; P = .049) than marginal resection; 21.3% of the AFS patients died due to complications related to the lesion. Very long follow-up is recommended for AF lesions, due to the risk of recurrence and malignant change into AFS. Segmental resection is the most recommended therapy for AFS. © 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

  19. Fibroma osificante periférico: caso clínico

    OpenAIRE

    Zoila Beatriz Carbonell Muñoz

    2013-01-01

    ResumenEl fibroma osificante periférico es una lesión reactiva, se considera que se origina de las células del ligamento periodontal; son lesiones benignas de tejido conectivo con focos de calcificación generalmente asintomáticas. En este artículo se presenta un caso de fibroma osificante periférico, permitiendo destacar la importancia clínica de este tipo de patología poco frecuente y con una actualizada revisión de literatura se busca afianzar conocimientos que conlleven a un correcto diagn...

  20. A huge cemento-ossifying fibroma of paranasal sinus: a case report.

    Science.gov (United States)

    Erdim, Ibrahim; Yazici, Zahide Mine; Yilmazer, Rasim; Sever, Nurten; Kayhan, Fatma Tulin

    2012-01-01

    Cemento-ossifying fibroma is a well-bordered, slow-growing, benign fibro-osseous disease. Although its localization is generally in the mandible, it can be seen in any area of the craniofacial region. Radiology and histopathology help to diagnose the condition. Treatment is based on close observation and/or surgical excision. In this case, we report the case of a 62-year-old male patient who had a large radiological appearance, cemento-ossifying fibroma in the paranasal sinuses.

  1. En bloc resection of huge cemento-ossifying fibroma of mandible: avoiding lower lip split incision.

    Science.gov (United States)

    Ayub, Tahera; Katpar, Shahjahan; Shafique, Salman; Mirza, Talat

    2011-05-01

    Cemento-ossifying Fibroma (COF) is an osteogenic benign neoplasm affecting the jaws and other craniofacial bones. It commonly presents as a progressively slow growing pathology, which can sometimes attain an enormous size, causing facial deformity. A case of a huge cemento-ossifying fibroma, appearing as a mandibular dumbell tumour in a male patient is documented, which caused massive bone destruction and deformity. It was surgically removed by performing en bloc resection of mandible avoiding the splitting of lower lip incision technique, thereby maintaining his normal facial appearance.

  2. A peculiar fibroma-like lesion of superficial soft tissue: morphologic and immunophenotypic evaluation.

    Science.gov (United States)

    Filotico, M; Damuri, A; Filotico, R

    2014-12-01

    Apeculiar lesion of superficial soft tissue characterised by fibroma-like morphology and an immunohistochemical profile consisting of CK+, VIM+, CD34+, CD31+/-, FLI1+ and INI-1 retained is described. The lesion entered into differential diagnosis with the so-called fibroma-like variant of epithelioid sarcoma, with the entities defined as ES-like/pseudomyogenic haemangioendothelioma and the recently identified entity defined as superficial CD34+ fibroblastic tumour. All of these entities share a common morphological structure, but differ in their immunophenotypic profile.

  3. Chondromyxoid fibroma of the clavicle extending to the adjacent joint: a case report.

    Science.gov (United States)

    Aggarwal, Aditya; Bachhal, Vikas; Soni, Ashwani; Rangdal, Sushil

    2012-12-01

    Chondromyxoid fibroma is a rare benign bone tumour usually involving bones of the lower extremity in young adults. We present a case of chondromyxoid fibroma of the left clavicle extending to the adjacent joint in a 84-year-old man. The tumour had breached the hyaline cartilage of acromioclavicular joint. The tumour was excised en bloc, and the humeral head was curetted and grafted with autogenous cancellous bone. Postoperatively, the patient had an uneventful recovery and regained excellent function of the left shoulder without any pain or stiffness. At the 18-month follow-up, there was no sign of recurrence.

  4. Desmoplastic fibroma of ulna: Excision and reconstruction of olecranon with a fibular graft

    Directory of Open Access Journals (Sweden)

    Tarun Goyal

    2013-01-01

    Full Text Available Desmoplastic fibroma is a rare, well differentiated, locally aggressive fibrous tumor usually arising from soft tissues, and rarely from bones. Involvement of forearm bones is extremely unusual. We present a large desmoplastic fibroma of right ulna in a 15-year-old male. The tumor was excised with a wide margin, and the bony defect was reconstructed with nonvascular autologous fibular graft. Reconstruction of the olecranon process was attempted using the fibular head and the remaining olecranon. At 2-years followup, there was no recurrence, flexion extension arc of the elbow joint was 40°-130° and there was no restriction of activities of daily living.

  5. Desmoplastic fibroma in the thoracic spine: an unusual localization of a rare primary bone tumor

    Energy Technology Data Exchange (ETDEWEB)

    Juergens, K.U.; Link, T.M.; Heindel, W. [Muenster Univ. (Germany). Inst. fuer Klinische Radiologie; Bullmann, V. [Dept. of Orthopedic Surgery, Univ. of Muenster (Germany); Brinkschmidt, C. [Gerhard Domagk Inst. of Pathology, Univ. of Muenster (Germany)

    2001-02-01

    A case of an intraspinal growing desmoplastic fibroma of the thoracic spine (T9-T11) is reported. Desmoplastic fibroma is a rare tumor of connective tissue that shows a locally infiltrative and destructive growth. An affection of the thoracic spine is an extremely rare manifestation. Preoperative CT documents the extent of osseous destruction and tumor associated cortical erosion. In central tumor areas an inhomogeneous, intermediate to low signal is demonstrated by MRI using T1- and T2-weighted spin-echo and turbo-spin-echo sequences. Contrast-enhanced MRI shows marked enhancement in peripheral areas depicting the extraosseous and intramedullary extension. (orig.)

  6. Fibroma osificante periférico: caso clínico

    OpenAIRE

    Zoila Beatriz Carbonell Muñoz

    2013-01-01

    ResumenEl fibroma osificante periférico es una lesión reactiva, se considera que se origina de las células del ligamento periodontal; son lesiones benignas de tejido conectivo con focos de calcificación generalmente asintomáticas. En este artículo se presenta un caso de fibroma osificante periférico, permitiendo destacar la importancia clínica de este tipo de patología poco frecuente y con una actualizada revisión de literatura se busca afianzar conocimientos que conlleven a un correcto diagn...

  7. A rare presentation of mucocele and irritation fibroma of the lower lip

    Directory of Open Access Journals (Sweden)

    B N Rangeeth

    2010-01-01

    Full Text Available The effects of chronic local irritation have been seen commonly in the form of fibroma or mucocele in children. We report a nine year old girl with the chief complaint of multiple swellings in the lower lip which was diagnosed both clinically and histologically as fibroma and mucocele. Surgical excision was done under local anesthesia with no post-operative complications. To our knowledge there was no other occurrence, either at the same site or at different locations, involving these two lesions in the oral mucosa.

  8. [A case reported of an ameloblastic fibroma in which involved three right molars in a teenager].

    Science.gov (United States)

    Ruiz-Ortega, Susana; Tovar-Bernal, Cuauhtémoc; Soriano-Padilla, Fernando

    2011-01-01

    Ameloblastic fibroma is a benign tumor of mixed odontogenic origin, which occurs in ages from 12 to 15 years, frequently in the molar area. Generally it is asymptomatic, however the biggest lesions can be associated to pain and swelling. Using X-ray they appear well defined, transparent, with a sclerotic radio-opaque border; occasionally they can simulate a dentigerous cyst. The treatment is generally conservative. This report describes an ameloblastic fibroma in a 14-year-old male, which involved the three right molars and both the ascending ramous and the coronoid process, which was treated conservatively with the extraction of the affected teeth, tumor extirpation and osseous curettage.

  9. METAPHYSEAL FIBROUS DEFECTS AND NONOSSIFYING BONE FIBROMA IN CHILDREN: CLINICAL TYPES AND TREATMENT

    Directory of Open Access Journals (Sweden)

    Николай Георгиевич Чигвария

    2014-06-01

    Full Text Available The paper presents the results of a comprehensive examination and treatment of 158 children and adolescents with nonossifying bone fibroma and skeleton, who referred for specialized medical aid in clinic of Scientific and Research Institute for Children's Orthopedics n. a. G. I. Turner from 1980 to 2013. We defined diagnostic value and the criteria for identifying lesions using X-ray, computed tomography and radionuclide methods. We emphasized the dynamic variability of clinical and radiological manifestations of the pathological process in nonossifying bone fibroma and skeleton and related difficulties in the diagnosis. Accurate indications for the conservative and surgical treatment were pointed out.

  10. Calcifying Aponeurotic Fibroma with Osseous Involvement of the Finger: a Case Report with Radiologic and US Findings

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Soo Jung; Ahn, Jae Hong; Kang, Gil Hyun; Lee, Jong Hyeog; Park, Man Soo; Ryu, Dae Sik; Jung, Seung Moon [GangNeung Asan Hospital, University of Ulsan College of Medicine, Gangneung (Korea, Republic of)

    2008-02-15

    Calcifying aponeurotic fibroma is a rare soft tissue tumor that occurs in the distal extremities of children and adolescents. We report ultrasound and X-ray findings of a calcifying aponeurotic fibroma in the finger of a 36-year-old woman, associated with distal phalangeal bone involvement. Calcifying aponeurotic fibroma is a rare, locally aggressive fibroblastic lesion occurring primarily in the palms of the hands and soles of the feet in young children and adolescents under 20 years of age. Clinical presentation is a unique, hard, and painless palpable mass. This soft tissue tumor typically infiltrates into the surrounding fascia or muscle and has a predilection for recurrence after surgical removal. However, bone involvement in calcifying aponeurotic fibroma is a very rare condition and we found only three pediatric cases in the literature. We present the ultrasound and radiographic findings of a calcifying aponeurotic fibroma in the finger of a 36-year-old woman, associated with erosive bone destruction of the distal phalanx. In summary, calcifying aponeurotic fibroma is a rare soft tissue tumor that presents as a painless mass primarily on the volar surface of the hands and plantar aspects of the feet in juveniles, but this tumor should be also included in differential diagnoses of any mass with calcification and adjacent bone involvement in the distal phalanx of the finger. In addition, US could be useful for the preoperative evaluation of digital calcifying aponeurotic fibroma.

  11. Cardioverter-defibrillator implantation to treat cardiac fibroma-induced ventricular tachycardia in a 70-year-old woman.

    Science.gov (United States)

    Hakim, Fayaz Ahmad; Pandit, Anil; Mookadam, Farouk; Mamby, Sylvia

    2014-06-01

    Benign cardiac fibroma is rarely reported in adults. Its clinical symptoms are related to outflow obstruction or dysrhythmias. We present the case of a 70-year-old woman who had a syncopal episode from ventricular tachycardia caused by cardiac fibroma. Because of unfavorable tumor anatomy, the patient was not a candidate for surgical excision, and she declined orthotopic heart transplantation. To prevent sudden cardiac death, we placed an implantable cardioverter-defibrillator, and the patient remained well throughout the 2-year follow-up period. To our knowledge, this is the first report of implantable cardioverter-defibrillator therapy to treat an adult patient's unresectable cardiac fibroma.

  12. The complete genome sequence of shope (rabbit) fibroma virus.

    Science.gov (United States)

    Willer, D O; McFadden, G; Evans, D H

    1999-11-25

    We have determined the complete DNA sequence of the Leporipoxvirus Shope fibroma virus (SFV). The SFV genome spans 159.8 kb and encodes 165 putative genes of which 13 are duplicated in the 12.4-kb terminal inverted repeats. Although most SFV genes have homologs encoded by other Chordopoxvirinae, the SFV genome lacks a key gene required for the production of extracellular enveloped virus. SFV also encodes only the smaller ribonucleotide reductase subunit and has a limited nucleotide biosynthetic capacity. SFV preserves the Chordopoxvirinae gene order from S012L near the left end of the chromosome through to S142R (homologs of vaccinia F2L and B1R, respectively). The unique right end of SFV appears to be genetically unstable because when the sequence is compared with that of myxoma virus, five myxoma homologs have been deleted (C. Cameron, S. Hota-Mitchell, L. Chen, J. Barrett, J.-X. Cao, C. Macaulay, D. Willer, D. Evans, and G. McFadden, 1999, Virology 264, 298-318). Most other differences between these two Leporipoxviruses are located in the telomeres. Leporipoxviruses encode several genes not found in other poxviruses including four small hydrophobic proteins of unknown function (S023R, S119L, S125R, and S132L), an alpha 2, 3-sialyltransferase (S143R), a protein belonging to the Ig-like protein superfamily (S141R), and a protein resembling the DNA-binding domain of proteins belonging to the HIN-200 protein family S013L). SFV also encodes a type II DNA photolyase (S127L). Melanoplus sanguinipes entomopoxvirus encodes a similar protein, but SFV is the first mammalian virus potentially capable of photoreactivating ultraviolet DNA damage.

  13. [Desmoplastic fibroma. Differential diagnosis of a periapical lesion from endodontic failure].

    Science.gov (United States)

    Zabalegui, B; Gil, J; Zabalegui, I

    1989-01-01

    Treatment of endodontically involved teeth requires accurate diagnosis of the clinical pulpal condition to determine the primary cause of pathosis. The case presented shows the differential diagnosis between a desmoplastic fibroma and a failure of a misdiagnosed endodontic treatment. The initial direction of treatment should had never been the endodontic therapy but local surgical curettage of the lesion.

  14. Juvenile ossifying fibroma of the maxilla: A rare aggressive case in a young patient

    Directory of Open Access Journals (Sweden)

    Marco Cicciù

    2013-01-01

    Here reported is a case of a six-year-old girl who developed a rare aggressive fibroma localized in the right upper jaw. The clinical, radiographic and histopathologic findings, plus differential diagnoses of the case and treatement options are also presented.

  15. JUVENILE OSSIFYING FIBROMA - AN ANALYSIS OF 33 CASES WITH EMPHASIS ON HISTOPATHOLOGICAL ASPECTS

    NARCIS (Netherlands)

    SLOOTWEG, PJ; PANDERS, AK; KOOPMANS, R; NIKKELS, PGJ

    1994-01-01

    Juvenile ossifying fibroma (JOF) is a maxillofacial fibro-osseous lesion that may show cell-rich osteoid strands or psammoma-like ossicles. Whether both types are variants of a single entity or different lesions under the same diagnostic label is a subject of debate. This problem was investigated by

  16. Desmoplastic fibroma of the mandible - review of the literature and presentation of a rare case

    Directory of Open Access Journals (Sweden)

    Engers Rainer

    2009-11-01

    Full Text Available Abstract Desmoplastic fibroma (DF is a rare, benign but locally aggressive, intraosseous lesion with a high tendency of local recurrence. In this report the actual literature is reviewed regarding epidemiological data, pathology, clinical diagnostic criterias, therapy and prognosis. Moreover, a report of an interesting case is included localized in the mandibular corpus.

  17. Aggressive psammomatoid ossifying fibroma of the inferior turbinate and lateral nasal wall.

    NARCIS (Netherlands)

    Danielides, V.; Ingels, K.J.A.O.; Patrikakos, G.; Wilde, P.C.M. de

    2003-01-01

    OBJECTIVE: Fibroosseous lesions are rare entities of the nose and paranasal sinuses, the terminology and classification of which are still confusing. Psammomatoid or aggressive (juvenile) ossifying fibroma is a benign messenchymal tumor usually met in the young age (5-15 years), in the sinonasal tra

  18. Intraoperative cardiac mapping in the treatment of an infant congenital fibroma.

    Science.gov (United States)

    Sakamoto, Shun-Ichiro; Shibata, Masafumi; Murata, Hiroshige; Nitta, Takashi

    2015-03-01

    Surgical treatment for ventricular tachycardia associated with congenital cardiac tumors is rare. Intraoperative electroanatomic mapping was performed in a 23-month-old female infant to identify the arrhythmogenic substrate of the epicardium before tumor resection. Verification of the localized abnormal electrocardiogram on the tumor in the treatment of ventricular tachycardia was useful for successful partial resection and cryoablation of the giant fibroma.

  19. Value of Dynamic Enhanced MR Imaging for the Differential Diagnosis between Ovarian Fibroma and Subserosal Leiomyoma

    Institute of Scientific and Technical Information of China (English)

    JunShan; XioomeiWang; JianminXu; HongliXu; XiaofengFeng; JingshanGong; RennanLing; ZibinRao

    2004-01-01

    OBJECTIVE To study the value of dynamic enhanced MR imaging in the differential diagnosis between ovarian fibroma and subserosal leiomyoma, both of which produce a intermediate to low signal intensity on T2W1. METHODS Plain and dynamic enhanced MRI results of 45 patients were analyzed, 35 cases of which were subserosal leiomyoma and 10 were ovarian fibroma. All of the tumors were verified by histologic analysis. RESULTS The 10 ovarian fibroma cases showed low signal intensities on T1W1, but 2 produced intermediate signal intensities and 8 showed low signal intensities on T2W1. There was little enhancement of the early phase and the delayed phase was long, so the enhancement index of the early phase (SI100) was low and the time to peak (TTP200) was long. Of the 35 subserosal leiomyoma cases, all showed low signal intensity on TlWl, 7 were intermediate in signal intensity and 28 generated a low signal intensity on T2W1. The enhancement of the early phase was moderate to highlyevident and the index was high. The time to peak was short (TTP200). The enhancement -time curve was different in the two groups, and the differencehad statistical sianificance (P<0.001). CONCLUSION Dynamic enhanced MR imaging was helpful in the differential diagnosis between ovarian fibroma and subserosal leiomyoma by the difference of the early phase enhancement.

  20. JUVENILE OSSIFYING FIBROMA - AN ANALYSIS OF 33 CASES WITH EMPHASIS ON HISTOPATHOLOGICAL ASPECTS

    NARCIS (Netherlands)

    SLOOTWEG, PJ; PANDERS, AK; KOOPMANS, R; NIKKELS, PGJ

    1994-01-01

    Juvenile ossifying fibroma (JOF) is a maxillofacial fibro-osseous lesion that may show cell-rich osteoid strands or psammoma-like ossicles. Whether both types are variants of a single entity or different lesions under the same diagnostic label is a subject of debate. This problem was investigated by

  1. Phenomenology of Extra Dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Hewett, J.L.; /SLAC

    2006-11-07

    If the structure of spacetime is different than that readily observed, gravitational physics, particle physics and cosmology are all immediately affected. The physics of extra dimensions offers new insights and solutions to fundamental questions arising in these fields. Novel ideas and frameworks are continuously born and evolved. They make use of string theoretical features and tools and they may reveal if and how the 11-dimensional string theory is relevant to our four-dimensional world. We have outlined some of the experimental observations in particle and gravitational physics as well as astrophysical and cosmological considerations that can constrain or confirm these scenarios. These developing ideas and the wide interdisciplinary experimental program that is charted out to investigate them mark a renewed effort to describe the dynamics behind spacetime. We look forward to the discovery of a higher dimensional spacetime.

  2. Qubits from extra dimensions

    CERN Document Server

    Lévay, Péter

    2011-01-01

    We link the recently discovered black hole-qubit correspondence to the structure of extra dimensions. In particular we show that for toroidal compactifications of type IIB string theory simple qubit systems arise naturally from the geometrical data of the tori parametrized by the moduli. We also generalize the recently suggested idea of the attractor mechanism as a distillation procedure of GHZ-like entangled states on the event horizon, to moduli stabilization for flux attractors in F-theory compactifications on elliptically fibered Calabi-Yau four-folds. Finally using a simple example we show that the natural arena for qubits to show up is an embedded one within the realm of fermionic entanglement of quantum systems with indistinguishable constituents.

  3. SCONUL Research Extra

    Directory of Open Access Journals (Sweden)

    John Hall

    2006-04-01

    Full Text Available SCONUL Research Extra is a cooperative access and borrowing scheme for staff and research students in UK and Irish higher education institutions. Under the terms of the scheme, eligible researchers may visit any participating library and register as an external borrower. The scheme is run on behalf of SCONUL, the Society of College, National and University Libraries which represents the directors of the library and information services in all the universities of the United Kingdom and Ireland, and in most other UK institutions of higher education, and the directors of the national libraries; it is for all institutions in membership of SCONUL able to lend library materials and, with 158 institutions signed up, it is now the largest reciprocal borrowing scheme in the UK and Ireland, serving almost the entire membership of SCONUL.

  4. Fibroma odontogenico en maxilar inferior. Apropósito de un caso

    Directory of Open Access Journals (Sweden)

    Gustavo Guzmán

    2013-10-01

    Full Text Available Title: Mandibular odontogenic fibroma. A case report.Resumen: Los tumores benignos son neoplasias que se pueden presentar en cualquier parte de la cavidad oral estos pueden ulcerarse, sangrar o interferir con la masticacion o con la adhesion de protesis dentales, tambien presentan un desarrollo lento, una superficie mucosa conservada y compresion de estructuras vecinas. Los fibromas odontogenicos son tumores benigno poco frecuente caracterizado por tejido fibroso con celulas de tejido conectivo, este se puede presentar en cualquier etapa de la vida, no tiene predileccion de sexo y se da mas en la mandibula que en los maxilares. El objetivo de este artículo es describir un caso clínico de este tumor, hacer una breve revisión de la literatura, analizar sus características clínicas e histológicas y la actitud terapéutica a tomar.(DUAZARY 2012 No.2, 190 - 195AbstractBenign tumors are growths that can occur in any part of the oral cavity they can ulcerate, bleed, or interfere with chewing or the adhesion of dental prostheses, also show a slow development, a preserved mucosal surface and compression of adjacent structures. Odontogenic fibroma is a fairly common tumor tissue characterized by fibrous connective tissue cells, this can occur at any stage of life, has no sex predilection an occurs more in the mandible than the maxilla. The aim of this paper is to describe a case of this tumor, a brief review of the literature, analyze their clinical and histological features and therapeutic approach to take.Keywords: Ossifying fibroma; benign neoplasms; fibromas; Jaw Neoplasms.

  5. Fibroma osificante central en el maxilar superior: reporte de un caso y revisión de la literatura Central ossifying fibroma in the maxilla: a case report and review of the literatur

    Directory of Open Access Journals (Sweden)

    B.R. Chrcanovic

    2011-02-01

    Full Text Available El fibroma osificante central (fibroma cementificante / fibroma cemento osificante es un tumor benigno óseo bien delimitado, se localiza principalmente en los maxilares aunque se puede presentar en los huesos orbital, frontal, paranasal y temporal. Se caracteriza por presentar un crecimiento y una tumefacción deformante de evolución lenta con una incidencia mayor en la mandíbula. El tratamiento consiste en la extirpación quirúrgica de la lesión. En este artículo se presenta un caso de fibroma osificante central localizado en la región posterior derecha del maxilar superior, de gran dimensión, que acomete a una paciente de sexo femenino de 46 años de edad, revelando datos clínicos, aspectos diagnósticos, imagenológicos, histopatológicos así como su tratamiento.Central ossifying fibroma (cementing fibroma / cemento ossifying fibroma is a bone benign tumor almost exclusively from maxillary region but can be in the orbital bones, frontal, paranasal and temporal. Progressive growth and disfiguring swelling of slow evolution are characteristics with more prevalence in the mandible. The treatment choice is a surgical excision of the lesion. This article presents a case of central ossifying fibroma located in the region of the right posterior maxilla of large dimension of a female patient of 46 years of age, describing clinical, diagnostic, imaging, and histopathological aspects as well as the treatment employed.

  6. Using Extra Credit to Facilitate Extra Learning in Students

    Directory of Open Access Journals (Sweden)

    Mohammad Muztaba Fuad

    2012-06-01

    Full Text Available Giving students extra credit work is a hotly debated pedagogical issue. This paper shares experience of using extra credit quizzes to push students to think critically and beyond the boundaries. This particular type of quizzes are not announced before and presented to students as a surprise quiz. A certain percentage of the grade earned in these quizzes was included in student’s final grade calculations. With a well-developed model of questions, quiz structure and grade calculation, the presented model of extra credit eliminates negativity related to extra credit work and also motivates students into course work. Our findings showed that by relieving students from the mental pressure of test taking and by making those tests/quizzes as extra credit; students actually performs better in solving harder problems and eventually learns more of the advanced course topics.

  7. Extra Low ENergy Antiproton

    CERN Multimedia

    To produce dense antiproton beams at very low energies (110 keV), it has been proposed to install a small decelerator ring between the existing AD ring and the experimental area. Phase-space blowup during deceleration is compensated by electron cooling such that the final emittances are comparable to the 5MeV beam presently delivered by the AD. An immediate consequence is a significant increase in the number of trapped antiprotons at the experiments as outlined in the proposal CERN/SPSC-2009-026; SPCS-P-338. This report describes the machine parameters and layout of the proposal ELENA (Extra Low ENergy Antiproton)ring also gives an approximate estimate of cost and manpower needs. Since the initial estimate, published in 2007 (CERN-AB-2007-079), the ELENA design has evolved considerably. This is due to a new location in the AD hall to acommodate for the possibility of another experimental zone, as suggested by the SPCS, and also due to improvements in the ring optics and layout. The cost estimate that is prese...

  8. Supersymmetry breaking with extra dimensions

    Indian Academy of Sciences (India)

    Fabio Zwirner

    2004-02-01

    This talk reviews some aspects of supersymmetry breaking in the presence of extra dimensions. The first part is a general introduction, recalling the motivations for supersymmetry and extra dimensions, as well as some unsolved problems of four-dimensional models of supersymmetry breaking. The central part is a more focused introduction to a mechanism for (super)symmetry breaking, proposed first by Scherk and Schwarz, where extra dimensions play a crucial role. The last part is devoted to the description of some recent results and of some open problems.

  9. Fibroma desmoplásico, reporte de un caso y revisión de la literatura Desmoplastic fibroma, report of a case and a literature review

    Directory of Open Access Journals (Sweden)

    C. Licéaga Escalera

    2010-03-01

    Full Text Available El fibroma desmoplásico es una lesión neoplásica relativamente rara. Se considera un tumor primario de hueso, que se presenta comúnmente en la región mandibular. Se define como un tumor benigno caracterizado por la formación de abundante matriz y fibras colágenas. En marzo de 2004 se presenta el caso de un paciente de 15 años, varón, con aumento gradual en la región derecha de la mandíbula de 4 meses de evolución. Se manifiesta asintomático, con aumento de volumen, con una apariencia radiográfica y tomográfica bien delimitada radiolúcida. A la exploración se observa un infiltrado a través de la cortical lingual. La lesión es similar a las descritas en la literatura de fibroma desmoplásico.Desmoplastic fibroma (fibromatosis is rarely seen a primary tumor of bone. Its occurrence as a central lesion in the jaws is even more uncommon. It is rare tumor of bone, especially in the mandibule. In march 2004, a 15 year-old boy presented, with a 4 month history of gradual enlargement of the right mandibule. Painless intraoral and extraoral swelling, the cortical plate of bone overlying the lesions is expanded with thinning, erosion, and infiltration into the surrounding tissues. The lesion is similar to the one described on the articule.

  10. Giant Cell Fibroma of Tongue: Understanding the Nature of an Unusual Histopathological Entity

    Directory of Open Access Journals (Sweden)

    Wanjari Ghate Sonalika

    2014-01-01

    Full Text Available Giant cell fibroma (GCF is a rare case with unique histopathology. It belongs to the broad category of fibrous hyperplastic lesions of the oral cavity. It is often mistaken with fibroma and papilloma due to its clinical resemblance. Only its peculiar histopathological features help us to distinguish it from them. The origin of the giant cell is still controversial. Data available is very sparse to predict the exact behavior. Hence, we report a case of GCF of tongue in a 19-year-old male. Special emphasis is given to understand the basic process of development of the lesion, nature of giant cells, and also the need for formation of these peculiar cells. Briefly, the differential diagnosis for GCF is tabulated.

  11. Facial reconstruction using polypropylene mesh after resection of maxillary ossifying fibroma

    Directory of Open Access Journals (Sweden)

    R. Soesanto

    2012-09-01

    Full Text Available Background: Ossifying fibroma is a variant of fibrous dysplasia and catagorized as osteofibrosis lesion. It commonly affects long bones but occasionally involves jaws. Mandible affected more common than maxilla. The treatment of ossifying fibroma include excision and resection. Excision of lesion and resection of maxilla could cause facial defect which cannot be reconstructed with bone graft. Purpose: The aim of this case report is to report the potential use of polypropylene mesh in facial reconstruction after hemimaxillectomy in patients diagnosed with ossifying fibroma of the maxilla. Case: A 17-years-old female patient came to Oral and Maxillofacial Surgery clinic, Dental Hospital, Faculty of Dentistry, Airlangga University, with chief complaint of swelling in the upper left cheek of 2 years duration which was not related to any history of toothache. Patient also complained of the itchiness and pain on the swelling area occasionally as well as salty discharge from the mass. The FNA was done and the citology result indicated a benign mesenchimal tumor. Incisonal biopsy was subsequently performed and the histopathology report confirmed the diagnosis of cementifying fibroma. Case management: Left hemimaxillectomy was done, and post surgical defect in the facial and buccal aspect was immediately reconstructed using three layers of polypropylene mesh. On follow-up, eleven months post-operatively, the patient was well and there was no facial deformity or asymmetry. Conclusion: Polypropylene mesh is a potential material for facial reconstruction as it can reduce the risk of facial deformity after hemimaxillectomy of patients with tumor of the maxilla.Latar belakang: Ossifying fibroma merupakan varian dari fibrous dysplasia dan termasuk di dalam kategori lesi osteofibrosis. Umumnya mengenai tulang panjang tetapi dapat juga mengenai rahang dan lebih banyak menyerang tulang mandibula dibanding maksila. Perawatan ossifying fibroma dilakukan dengan

  12. Giant cemento-ossifying fibroma of the mandible: a rare case.

    Science.gov (United States)

    Sujatha, D; Shubha, Gurudath; Anuradha, Pai; Ragavendra, Mahadev Naik

    2013-01-01

    The World Health Organization classifies cemento-ossifying fibroma (COF) as a fibro-osseous neoplasm included among the nonodontogenic tumors derived from the mesenchymal blast cells of the periodontal ligament, with a potential for forming fibrous tissue, cementum and bone, or a combination of such elements. These are slow-growing lesions, and are more frequent in women, between the third and fourth decades of life. Case reports of massive expansile COFs (measuring more than 10 cm) are rarely reported in the literature. This article aims to describe a case of giant cemento-ossifying fibroma with radiographic and 3D CT features in a 34 year old female patient, who came with the complaint of progressive swelling of the face which had started 6 years earlier.

  13. Juvenile aggressive cemento-ossifying fibroma of the sphenoid sinus with proptosis: a surgical dilemma.

    Science.gov (United States)

    Singh, Rohit; Ramaswamy, Balakrishnan; Hazarika, Manali

    2013-11-27

    The term fibro-osseous lesion has currently grown in popularity as an overall designation for a number of rare, histologically benign head and neck lesions that are made up of bone, fibrous tissue and cementum. Cemento-ossifying fibroma is a variant of cementifying fibroma and is a fibro-osseous disease. They are usually small innocuous lesions which follow a slow benign course and are commonly seen in the skull bone rather than the sphenoid. It is rare for these tumours to attain large size, behave aggressively, destroy bone and require a radical surgery. One such rapidly growing juvenile cemento-ossifying lesion of sphenoid in our 10-year-old young patient causing proptosis and impaired vision is reported here because of its uncommon nature and its surgical dilemma. Selection of surgical approach to resect this tumour becomes difficult because it is deeply seated and needs a multidisciplinary approach.

  14. Treatment and functional result of desmoplastic fibroma with repeated recurrences in the forearm: A case report

    Science.gov (United States)

    RUI, JING; GUAN, WENJIE; GU, YUDONG; LAO, JIE

    2016-01-01

    Desmoplastic fibroma, alternatively known as aggressive fibromatosis or desmoid tumors, occurs in the form of benign locally aggressive tumors that possess a high rate of recurrence. The forearm bones are rarely involved. The current study presents a case of desmoplastic fibroma in the distal forearm of a 23-year-old man. The tumor was widely resected, and the bone defect was reconstructed using an autologous vascularized fibular graft during the resection procedure. The patient experienced recurrence three times and underwent four resections during the subsequent 3 years following the initial resection. After 10 years of follow-up, the patient's functional recovery remains positive. Despite the implication that surgical resection may be involved in the development of aggressive fibromatosis, surgical wide local excision and functional reconstruction were recommended for the treatment of the present patient. PMID:26893769

  15. Enormous ovarian fibroma with elevated Ca-125 associated with Meigs' syndrome. Presentation of a rare case.

    Science.gov (United States)

    Sofoudis, C; Kouiroukidou, P; Louis, K; Karasaridou, K; Toutounas, K; Gerolymatos, A; Papamargaritis, E

    2016-01-01

    In medicine, Meigs' syndrome is the triad of ascites, pleural effusion, and benign ovarian tumor (fibroma, Brenner tumour, and occasionally granulosa cell tumour). It resolves after the resection of the tumor. Because the transdiaphragmatic lymphatic channels are larger in diameter on the right, the pleural effusion is classically on the right side. The etiologies of the ascites and pleural effusion are poorly understood. Atypical Meigs' syndrome,characterized by a benign pelvic mass with right-sided pleural effusion but without ascites, can also occur. As in Meigs syndrome, pleural effusion resolves after removal of the pelvic mass. The authors would like to share their own experience of a case of Meigs' syndrome associated with an enormous ovarian fibroma and elevated Ca-125.

  16. Mandibular ameloblastic fibroma in 6-years-old girl: a case report.

    Science.gov (United States)

    Anesi, A; Albanese, M; Gerosa, R; Corrocher, G; Gambarini, G; Nocini, P F

    2008-10-01

    Ameloblastic fibroma (AF) is defined in WHO classification as a ''neoplasm composed of proliferating odontogenic epithelium embedded in a cellular ectomesenchymal tissue that resembles dental papilla, and with varying degrees of inductive change and dental hard tissue formation''. AF is a rather uncommon tumor, accounting for only 2.5% of all odontogenic tumors. AF is a true mixed tumor, in which the epithelial and ectomesenchymal elements are neoplastic. AF raises at any age, ranging from 6 months to 42 years (mean 14.6 to 15.5 years); it does not show sex predilection. The lesion occurs in nearly 70% of cases in posterior areas of the mandible. Patients exhibit swelling of the jaw; pain is not usually described. Authors present a clinical and surgical management of an early onset of a large mandibular ameloblastic fibroma in a 6-year-old girsl.

  17. Ameloblastic fibroma: a rare case report with 7-year follow-up.

    Science.gov (United States)

    Melo, Leonardo de Araújo; Barros, Adna Conceição; Sardinha, Sandra de Cássia Santana; Cerqueira, Arlei; dos Santos, Jean Nunes

    2015-01-01

    Ameloblastic fibroma (AF) is a rare benign odontogenic tumor that usually occurs in the fi two decades of life. It affects adolescents and young adults and is found in the mandible and with a high frequency in the posterior region of this segment. There are rare case reports with a long-term follow-up. We report the case of a 6-year-old boy with extensive ameloblastic fibroma in the man ble. Treatment consisted of enucleation and bone curettage, with the preservation of permanent teE adjacent to the tumor. Clinical and radiographic follow-up of the patient over a period of 7 years show no signs of recurrence or malignant transformation. Patients with AF should be under follow-up for prolonged periods of time, even in ca! exhibiting a low proliferation index, because of the potential for recurrence and malignant transformation of this tumor.

  18. Ameloblastic fibroma: A rare case report with 7-year follow-up

    Directory of Open Access Journals (Sweden)

    de Araújo Melo Leonardo

    2015-01-01

    Full Text Available Introduction. Ameloblastic fibroma (AF is a rare benign odontogenic tumor that usually occurs in the first two decades of life. It affects adolescents and young adults and is found in the mandible and with a higher frequency in the posterior region of this segment. There are rare case reports with a long-term follow-up. Case Outline. We report the case of a 6-year-old boy with extensive ameloblastic fibroma in the mandible. Treatment consisted of enucleation and bone curettage, with the preservation of permanent teeth adjacent to the tumor. Clinical and radiographic follow-up of the patient over a period of 7 years showed no signs of recurrence or malignant transformation. Conclusion. Patients with AF should be under follow-up for prolonged periods of time, even in cases exhibiting a low proliferation index, because of the potential for recurrence and malignant transformation of this tumor.

  19. Fibroma ameloblástico. Reporte de un caso clínico

    OpenAIRE

    Gustavo Guzmán; Edder Chamorro Flórez; Ramiro Gutiérrez Hoyos

    2013-01-01

    Title: Ameloblastic fibroma. Report of a case report.ResumenEl fibroma ameloblástico (FA) es un tumor benigno odontogénico mixto (estroma fibroso y epitelial) de rara aparición, que constituye el 2% de todos los tumores odontogénicos. Se caracteriza por presentarse en pacientes jóvenes entre la primera y segunda década de la vida, sin predilección por el sexo y con tendencia de aparición en la mandíbula. Su tratamiento es variado, ya que el mismo va a depender del tamaño de la lesión, de la e...

  20. Fibroma aponeurótico calcificante intra articular. Presentación de un caso.

    Directory of Open Access Journals (Sweden)

    José Ramón Hernández Puerto

    2010-02-01

    Full Text Available El fibroma aponeurótico juvenil es un tumor infrecuente del tejido blando que se localiza con mayor periodicidad en niños y adolescentes en la región distal de las extremidades, aunque se reportan casos en otras edades y localización. Se presenta un paciente de 18 años de edad, masculino con fibroma aponeurótico calcificante en la rodilla derecha intra articular, con una localización poco común. El diagnóstico se realizó por exéresis quirúrgica del tumor. Se hace referencia al cuadro clínico, terapéutica efectuada y seguimiento por 3 años. Se revisó literatura actualizada referente al tema. Por ser un caso infrecuente se decide su publicación.

  1. Inflation from periodic extra dimensions

    CERN Document Server

    Higaki, Tetsutaro

    2016-01-01

    We discuss a realization of a small field inflation based on string inspired supergravities. In theories accompanying extra dimensions, compactification of them with small radii is required for realistic situations. Since the extra dimension can have a periodicity, there will appear (quasi-)periodic functions under transformations of moduli of the extra dimensions in low energy scales. Such a periodic property can lead to a UV completion of so-called multi-natural inflation model where inflaton potential consists of a sum of multiple sinusoidal functions with a decay constant smaller than the Planck scale. As an illustration, we construct a SUSY breaking model, and then show that such an inflaton potential can be generated by a sum of world sheet instantons in intersecting brane models on extra dimensions containing $T^2/{\\mathbb Z}_2$ orbifold. We show also predictions of cosmic observables by numerical analyzes.

  2. Management of a posterior mediastinal Gardner fibroma causing critical airway stenosis in a resource limited setting

    Directory of Open Access Journals (Sweden)

    Katie Clouthier, DO

    2017-05-01

    Full Text Available In developed countries, surgeons and anesthesiologists approach the mediastinal mass causing airway compression with prudence and trepidation. Resource-limited settings provide unique challenges in the diagnosis and management of patients with critical airway compression. We report the successful treatment of a patient in Port-au-Prince, Haiti with a posterior mediastinal mass that filled the left chest cavity and caused critical airway stenosis. The pathology revealed a Gardner Fibroma, which is rarely associated with mediastinal airway obstruction.

  3. Ovarian Fibroma with Meigs Syndrome associated with Elevated CA125 - A Rare Case

    Directory of Open Access Journals (Sweden)

    Prasad. K. Shetty

    2010-07-01

    Full Text Available Postmenopausal women with solid adnexal masses, ascites and pleural effusion with elevated CA 125 are highly suggestive for malignant ovarian tumor. However in literature 28 cases Meigs syndrome (Benign ovarian tumor, ascites and right pleural effusion with raised CA 125 have been reported. We report a case of Meigs syndrome caused by right ovarian fibroma with elevated serum CA125 level in a postmenopausal woman

  4. [Successful excision of a left ventricular fibroma in an adult patient; report of a case].

    Science.gov (United States)

    Okada, Shuichi; Kaneko, Tatsuo; Ezure, Masahiko; Hasegawa, Yutaka; Kimura, Chieri; Okonogi, Shuichi; Takihara, Hitomi; Naito, Noritsugu

    2014-07-01

    A 55-year-old man was referred with a diagnosis of a left ventricular thrombus. Echocardiography revealed that he had a thrombus in the free wall of the left ventricle. Under cardiopulmonary bypass, we removed the intramural tumor. After the removal, the defect was repaired by Dor operation. Pathological examination revealed the tumor was a cardiac fibroma. He is doing well without any troubles 3 years after the operation.

  5. CT diagnosis in the thecoma-fibroma group of the ovarian stromal tumors.

    Science.gov (United States)

    Zhang, Zhixu; Wu, Yan; Gao, Jianbo

    2015-03-01

    The aim of this study was to investigate characteristic CT manifestations of the group of ovarian thecoma-fibroma. 24 patients (26 lesions) presenting with the ovarian thecoma-fibroma were analyzed retrospectively, and the diagnosis were confirmed by pathology after surgery. Our findings included: 22 patients were unilateral, while 2 were bilateral; 12 lesions were located in the right side of ovary, while 14 lesions were in the left side. Of the 26 lesions, there were ovarian thecoma (16 lesions), fibrothecoma (6 lesions), and fibroma (4 lesions). The largest diameters of tumor ranged from 37 to 231 mm with the mean value of 100 ± 44.29 mm. 14 patients were accompanied by ascites. All the tumors had well-defined borders. The shape of  22 lesions appeared round or oval, and 4 lesions were irregular. The tumors were solid in 19 lesions, cystic in 2 lesions, and mixed in 5 lesions. Most of the tumors were of heterogeneous density. There were no (20 lesions) or slight enhancement (6 lesions) after injection of the contrast medium. CT values of plain scan, arterial phase and venous among three groups had no significant difference. The enhancement were in the range of 0-5 HU in 10 lesions, and 6-17 HU in 16 lesions. In conclusion, the characteristic CT manifestations of the group of ovarian thecoma-fibroma were: often unilateral solid mass with the shape of oval and well defined border; no enhancement or slight enhancement; accompanied by small amount of ascites.

  6. Ameloblastic fibroma in six–year-old male: Hamartoma or a true neoplasm

    Science.gov (United States)

    Jindal, Chhavi; Bhola, Reena Sarkar

    2011-01-01

    Ameloblastic fibroma (AF) is an uncommon true mixed odontogenic tumor with a relative frequency between 1.5% and 4.5%. Recently, it has been proposed that two subtypes of AF exist: A neoplasm and a hamartomatous lesion. We report a case of AF in left mandibular posterior region in a 6-year-old male patient. The tumor showed unusual and aggressive features that suggested it was a true neoplasm. PMID:22144834

  7. Ameloblastic fibroma in six-year-old male: Hamartoma or a true neoplasm.

    Science.gov (United States)

    Jindal, Chhavi; Bhola, Reena Sarkar

    2011-09-01

    Ameloblastic fibroma (AF) is an uncommon true mixed odontogenic tumor with a relative frequency between 1.5% and 4.5%. Recently, it has been proposed that two subtypes of AF exist: A neoplasm and a hamartomatous lesion. We report a case of AF in left mandibular posterior region in a 6-year-old male patient. The tumor showed unusual and aggressive features that suggested it was a true neoplasm.

  8. Khan Krum - ʺThe Fearsomeʺ: A Noble Bulgarian with Iris-Fibroma?

    Directory of Open Access Journals (Sweden)

    Georgi Tchernev

    2017-08-01

    Full Text Available A 40-year-old Caucasian, the otherwise healthy male patient, presented with 3-years history of a prominent tumor-like formation, located on his back, without subjective complaints. Initially, the lesion was 1-2 cm in size but gradually increased to a visible-pronounced tumor-like formation. No other dermatologic diseases, neither other known abnormalities were reported for the medical and family history.  Softly-elastic on palpation tumor-like formation was established in the left infrascapular area of the back, measuring 8/9 cm in diameter. The lesion was clinically suspected for lipoma or another soft-tissue tumour with benign nature, so the patient underwent planned surgical excision under local anaesthesia. A tumour was excited with deep elliptical excision and furthered for histological evaluation, while the wound edges were sutured with single cutaneous stitches. Additionally, a large black-colored tattoo of the Bulgarian historical noble Khan Krum was also observed within the clinical examination, covering almost the whole upper 1/3 part of the patient’s back Within the careful clinical observation of the tattoo, we noticed a fibroma-like lesion, affecting the noble’s right iris. Fibromas are common benign tumours in Caucasians, composed of fibrous or connective tissue. They can be seen in all organs from mesenchymal tissue, in varies size. Eyelids are often commonly affected in elderly. Although very commonly seen in every day dermatological practice, fibromas have been never reported, located in the iris. In the presented case, a small ʺiris-fibromaʺ, hidden within a black-colored tattoo was diagnosed in a patient with lipoma, as a sporadic clinical finding.

  9. Periodontal Plastic Surgical Repair Following Removal of a Recurrent Peripheral Odontogenic Fibroma

    OpenAIRE

    Soileau, Kristi M.

    2013-01-01

    The purpose of this case report was to present a case of a recurrent peripheral odontogenic fibroma, which required periodontal plastic surgery, due to resultant esthetic complications. This report describes a case of removal and biopsy of a large gingival lesion over the left maxillary central incisor, which recurred, thus requiring more aggressive treatment, followed by esthetic periodontal plastic surgery. After fourteen months, there was uneventful healing of the gingival and alveolar tis...

  10. Phenomenology of universal extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Kong, Kyoungchul; Matchev, Konstantin T.; /Florida U.

    2006-10-01

    In this proceeding, the phenomenology of Universal Extra Dimensions (UED), in which all the Standard Model fields propagate, is explored. We focus on models with one universal extra dimension, compactified on an S{sub 1}/Z{sub 2} orbifold. We revisit calculations of Kaluza-Klein (KK) dark matter without an assumption of the KK mass degeneracy including all possible coannihilations. We then contrast the experimental signatures of low energy supersymmetry and UED.

  11. Ovarian fibromas in pediatric patients with basal cell nevus (Gorlin) syndrome.

    Science.gov (United States)

    Ball, Allison; Wenning, Joan; Van Eyk, Nancy

    2011-02-01

    Gorlin syndrome is a rare genetic condition consisting of multiple basal cell nevi associated with other entities such as medulloblastoma, skeletal abnormalities, and ovarian fibromas. A 15-year-old girl presented with abdominal discomfort. Magnetic resonance imaging showed multiple bilateral solid adnexal masses, the largest measuring 5.5 cm × 6.1 cm × 5.6 cm. At laparoscopy, 10 ovarian fibromas, ranging from 3 mm to 7 cm in size, were removed from each ovary. Concurrent with her gynecologic course, she was found to have maxillary sinus cysts and multiple basal cell nevi. The patient's history was also significant for a medulloblastoma as an infant. Given this constellation of findings, a diagnosis of Gorlin syndrome was made. The development of ovarian fibromas in the pediatric population is rare. When diagnosed, the possibility of Gorlin syndrome must be considered. Furthermore, females with Gorlin syndrome would benefit from regular gynecologic surveillance. Copyright © 2011 North American Society for Pediatric and Adolescent Gynecology. Published by Elsevier Inc. All rights reserved.

  12. Cemento-ossifying fibroma in a patient with end-stage renal disease.

    Science.gov (United States)

    Gopinath, Divya; Beena, V T; Sugirtharaj, G; Vidhyadharan, K; Salmanul Faris, K; Kumar, Sajai J

    2013-01-01

    The presence of chronic renal disease (CRD) is a predisposing factor for the occurrence of soft and hard tissue lesions in the oral cavity. The cemento-ossifying fibroma (COF) is an uncommon benign fibroosseous lesion composed of fibrocellular component and calcified materials like cementum and woven bone. A 37-year-old female patient undergoing chronic haemodialysis reported to our institution with a complaint of slow growing, nontender swelling of mandible of 6-month duration. Computed tomography disclosed an ill-defined lesion showing thinning and expansion of buccal as well as lingual cortical plate with flecks of radiopacity in centre. Incision biopsy revealed histological characteristics consistent with cemento-ossifying fibroma. The lesion was excised under local anesthesia. The histopathological examination revealed irregularly shaped bone and cementum-like hard tissue calcifications contained within hypercellular fibrous tissue stroma, leading to a confirmation of the diagnosis of cemento-ossifying fibroma. This paper aims to provide light to the fact that the soft and hard tissues of the oral region may become susceptible to the development of pathological growths in case of some particular systemic conditions.

  13. Periosteal desmoplastic fibroma of the tibia in a 3-year-old child.

    Science.gov (United States)

    Sferopoulos, N K

    2015-12-01

    Desmoplastic fibroma is a rare benign fibrogenic, locally aggressive, primary bone tumor. It is the intraosseous counterpart of soft tissue aggressive fibromatosis. The lesion may very rarely appear as a superficial bone lesion arising from the periosteum; in such cases, a soft tissue mass with changes in the adjacent bone is evident. Periosteal lesions are very rare in the literature; diagnosis is usually based on the radiographic findings, and histological proof of the tumor origin is missing. A periosteal desmoplastic fibroma of the distal tibial metaphysis in a 3-year-old boy is presented. Radiographic investigation included plain radiographs and computed tomography imaging. Both demonstrated a soft tissue lesion involving the superficial bone tissues with non-aggressive looking borders and a pressure effect with a sclerotic rim in the bone. The lesion was excised, and the surgical as well as the histological findings indicated the diagnosis of a desmoplastic fibroma of bone arising from the periosteum. No recurrence was detected 5 years after surgery.

  14. Cemento-Ossifying Fibroma in a Patient with End-Stage Renal Disease

    Directory of Open Access Journals (Sweden)

    Divya Gopinath

    2013-01-01

    Full Text Available The presence of chronic renal disease (CRD is a predisposing factor for the occurrence of soft and hard tissue lesions in the oral cavity. The cemento-ossifying fibroma (COF is an uncommon benign fibroosseous lesion composed of fibrocellular component and calcified materials like cementum and woven bone. A 37-year-old female patient undergoing chronic haemodialysis reported to our institution with a complaint of slow growing, nontender swelling of mandible of 6-month duration. Computed tomography disclosed an ill-defined lesion showing thinning and expansion of buccal as well as lingual cortical plate with flecks of radiopacity in centre. Incision biopsy revealed histological characteristics consistent with cemento-ossifying fibroma. The lesion was excised under local anesthesia. The histopathological examination revealed irregularly shaped bone and cementum-like hard tissue calcifications contained within hypercellular fibrous tissue stroma, leading to a confirmation of the diagnosis of cemento-ossifying fibroma. This paper aims to provide light to the fact that the soft and hard tissues of the oral region may become susceptible to the development of pathological growths in case of some particular systemic conditions.

  15. Fibroma of tendon sheath of the hand: a series of 20 patients with 23 tumours.

    Science.gov (United States)

    Al-Qattan, M M

    2014-03-01

    Fibroma of tendon sheath is an uncommon fibrous tumour that has a predilection for the hand. Large series from Histopathological Units report a local recurrence rate of 24% after surgical excision. In the hand/orthopaedic surgery literature, fibroma of tendon sheath was generally reported as isolated case reports with unusual presentations, such as triggering and carpal tunnel syndrome. The current article reports on a series of 23 tumours of the hands of 20 patients. These were all adults (mean age of 36 years) with a male to female ratio of 3:1. The thumb and index were the most common sites. A slow-growing painless mass was the clinical presentation in every case. Total surgical excision was ensured by excision of part of flexor sheath/palmar fascia to which the tumour was attached. Diagnosis was confirmed by the classic histological features of fibroma of tendon sheath. There were no recurrences at final follow-up 2-5 years after surgery.

  16. Nonossifying fibroma (metaphyseal fibrous defect) of the mandible in a 15-year-old boy.

    Science.gov (United States)

    Mannan, Abul Ala; Singh, N Gopendro; Al-Waheeb, Salah; Taher, Taher N; Mohammed, Emad El Din El Din

    2015-06-01

    We describe a rare case of nonossifying fibroma of the mandible in a 15-year-old boy who presented with a left mandibular swelling. Conventional imaging showed an expansile radiolucent lesion involving the angle and the body of the left mandible. The lesion was curetted, and a miniplate was implanted at the excision site. Microscopic examination of the removed specimen revealed a cellular lesion characterized by a proliferation of uniform spindle-shaped cells in a vague but prominent storiform pattern, which represented the classic appearance of nonossifying fibroma. Three months later, radiography detected a fracture of the implantation plate. The area was re-explored with curettage of the soft tissue, which on microscopy demonstrated findings similar to the initial curettage findings. Follow-up radiology revealed satisfactory healing of the jaw, and no further recurrence was seen 2 years after the initial surgery. We present this case to highlight the importance of recognizing nonossifying fibroma in the mandible, which can be easily confused with more common mandibular lesions.

  17. Esophageal fibroma: a report of one case%食管纤维瘤1例

    Institute of Scientific and Technical Information of China (English)

    仲海艳; 严苏; 陈卫昌

    2011-01-01

    Fibroma is a benign tumor derived from fibrous connective tissue.Esophageal fibroma is a very rare form of benign esophageal tumor.Here, we report a case of esophageal fibroma in a 41-year-old female and review the relevant literature.%纤维瘤是来源于纤维结缔组织的良性肿瘤,因纤维瘤内合成分不同而有不同种类,纤维瘤可以发生于体内任何部位.食管良性肿瘤很少见,食管纤维瘤是食管良性肿瘤之一,此病非常罕见,国内外文献鲜有报道,临床上易误诊为平滑肌瘤.本文报道食管纤维瘤1例,通过病史及内镜检查、病理结果并结合文献进行分析讨论,提高对食管纤维瘤的认识.

  18. Ovarian fibromas: MR imaging findings with emphasis on intratumoral cyst formation

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Hiroki, E-mail: hkato@gifu-u.ac.jp [Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194 (Japan); Kanematsu, Masayuki, E-mail: masa_gif@yahoo.co.jp [Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194 (Japan); High-level Imaging Diagnosis Center, Gifu University Hospital, 1-1 Yanagido, Gifu 501-1194 (Japan); Ono, Hiromi, E-mail: hiromi11_br@yahoo.co.jp [Department of Radiology, Gifu University School of Medicine, 1-1 Yanagido, Gifu 501-1194 (Japan); Yano, Ryuichiro, E-mail: yanoryu@gifu-u.ac.jp [Department of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu (Japan); Furui, Tatsuro, E-mail: furui@gifu-u.ac.jp [Department of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu (Japan); Morishige, Ken-ichirou, E-mail: mken@gifu-u.ac.jp [Department of Obstetrics and Gynecology, Gifu University School of Medicine, Gifu (Japan); Hatano, Yuichiro, E-mail: yuha@gifu-u.ac.jp [Department of Pathology, Gifu University School of Medicine, Gifu (Japan)

    2013-09-15

    Purpose: The purpose of this study was to assess MR imaging findings of ovarian fibromas with emphasis on intratumoral cyst formation. Materials and methods: MR images with a 1.5-T unit obtained in 17 consecutive patients (age range, 18–87 years; mean age, 58 years) with 17 histologically proven ovarian fibromas were retrospectively reviewed for the size, configuration, signal intensity of solid components, and presence of cystic degeneration and edema within tumor. Size, number, and location of intratumoral cysts were also assessed. Results: The maximum diameter of tumors ranged from 3.3 to 19.1 cm (mean, 10.9 cm). Seven (41%) tumors were multinodular. On T2-weighted images, solid components of tumors were heterogeneously mixed hypo- and hyperintensity in 16 (94%) tumors. Nine (53%) tumors demonstrated cysts and 16 (94%) demonstrated edema within tumor. The maximum diameter of the largest cysts ranged from 1.0 to 13.2 cm (mean, 6.4 cm), and the number of cysts per tumor ranged from 1 to 60 (mean, 15.6). Of the nine tumors with cystic formation, the predominant location of the cysts was peripheral in five (56%), exophytic in two (22%), central (11%) in one, and diffuse in one (11%). Conclusion: Peripheral or exophytic cyst formation may be characteristic MR imaging features with ovarian fibromas.

  19. Hard Fibroma on Hip in Children%儿童臀部硬性纤维瘤

    Institute of Scientific and Technical Information of China (English)

    陶文芳; 胡佐民; 王凤兰; 马玉琳

    1985-01-01

    @@ 儿童臀部硬性纤维瘤有生长部位及病理组织学特点,故诊断与治疗上与一般纤维瘤有不同之处.我科自1976年至1982年6月共收治儿童臀部硬性纤维瘤7例.现报告如下: 临床资料 本组7例中,男5例、女2例.年龄在4~12岁.发生于右臀部者4例,左臀部者3例.肿瘤生长较为缓慢,多呈扁圆形突出,质地坚硬,与臀部固着,无活动性.肿瘤表面平滑,但境界多不甚清楚,亦无触痛.肿瘤较大者皆表现有髋关节活动受限,不同程度的跛行.%Hard fibroma on the hip is clinically uncommon in children. Its peculiarity of localization and pathology makes it different from common fibroma in diagnosis and treatment.In a period of 6 years,we treated 7 patients,5 males and 2 females,aged between 4 and 12,by resection of the fibroma.5 of them were followed up.3 who had received total resection of the fibroma recovered without local recurrence.Only 2 suffered from moderate cripple when walking fast. One of them had a piece of residual tumour on the neurilemma membrane of ischiastic nerve but displayed no obvious local change in the area of the lesion when followed up 2 years after operation. Another one again showed compression symptoms in the rectum and bladder as well as dysfunction of the sphincter. This paper also discusses about the pathology and resection of hard fibroma.

  20. Escisión de un fibroma de células gigantes con láser de diodo: Informe de un caso Excision of a giant cell fibroma with Diodo's Laser: Report of case

    Directory of Open Access Journals (Sweden)

    C.M. Ardila Medina

    2010-06-01

    Full Text Available Este artículo informa un caso de un fibroma gigantocelular localizado en tejido gingival y mucosa oral. Microscópicamente, la lesión se caracterizó por proliferación de fibras colágenas y fibroblastos gigantes, que se disponían en forma densa e irregular. Además, la superficie de la lesión estaba revestida por epitelio con cambios de hiperqueratosis. Se realizó escisión del fibroma con láser de diodo.This article reports a case of giant cell fibroma located in the gingival tissue and oral mucosa. Microscopically, the lesion was characterized by proliferation of collagen fibers and giant fibroblast, irregular and densely arranged. Beside, the surface was covered by epithelium with hiperqueratosis changes. The excision was done with Diodo's Laser.

  1. Extra Stimulation in Intermediate Grade Reading.

    Science.gov (United States)

    Mason, George E.

    Three types of extra stimulation in reading are discussed: extra teacher time devoted to teaching reading, extra student time devoted to practice in reading, and extra motivation and reinforcement leading to greater amounts of student reading outside the school. Problems are created (1) when teaching time spent on reading is increased in the…

  2. Collider searches for extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Landsberg, Greg; /Brown U.

    2004-12-01

    Searches for extra spatial dimensions remain among the most popular new directions in our quest for physics beyond the Standard Model. High-energy collider experiments of the current decade should be able to find an ultimate answer to the question of their existence in a variety of models. Until the start of the LHC in a few years, the Tevatron will remain the key player in this quest. In this paper, we review the most recent results from the Tevatron on searches for large, TeV{sup -1}-size, and Randall-Sundrum extra spatial dimensions, which have reached a new level of sensitivity and currently probe the parameter space beyond the existing constraints. While no evidence for the existence of extra dimensions has been found so far, an exciting discovery might be just steps away.

  3. Prepubertal vulval fibroma with a coincidental ectopic breast fibroadenoma: report of an unusual case with literature review.

    Science.gov (United States)

    Zhang, Jian; Chen, Yue; Wang, Kana; Xi, Mingrong; Yang, Kaixuan; Liu, Hui

    2011-11-01

    Prepubertal vulval fibroma and ectopic breast fibroadenoma of the vulva are two rare tumors, and they are very difficult to distinguish from other vulval masses, both clinically and pathologically. The complication of the two diseases is extremely rare. We report the case of an extremely large and progressively enlarging mass in the vulva of an 18-year-old Chinese girl. The mass was excised completely and pathologically diagnosed as a prepubertal vulval fibroma and ectopic breast fibroadenoma. The patient was followed up for 10 months and no evidence of recurrence was observed. Prepubertal vulval fibroma and vulval ectopic breast fibroadenoma should be considered in their preoperative differential diagnosis of a vulval mass, especially in prepubertal girls. Pathologically, immunohistochemical staining for vimentin and CD34 is valuable for diagnosis. Complete surgical excision is effective and long-term follow up is necessary.

  4. Chondromyxoid fibroma of the skull base: Differential diagnosis and radiotherapy. Two case reports and a review of the literature

    Energy Technology Data Exchange (ETDEWEB)

    Feuvret, Loic; Noel, Georges; Calugaru, Valentin [Inst. Curie, Orsay (France). Centre de protontherapie d' Orsay; Terrier, Philippe; Habrand, Jean-Louis [Inst. Gustave Roussy, Villejuif (France)

    2005-09-01

    Chondromyxoid fibromas are uncommon tumours mostly arising in long bones of young males. Involvement of the skull base is extremely rare. We describe two new cases of base of the skull chondromyxoid fibromas. The tumours were incompletely excised and irradiated with protons because of the high risk of complications of another surgical procedure. The rationale for proton therapy was based on the intimate relations between the tumour and the organs at risk. Skull base chondromyxoid fibroma is a very rare, slowly growing benign tumour that can cause severe disabilities due to tumour compression of critical structures. Only surgical resection has been shown to be relatively effective. We report two cases of incompletely excised lesions treated by postoperative high-dose radiation including proton therapy with no active disease and complication. Our review of the literature allows us to conclude that histological diagnosis of lesions in this site is a trap for pathologists and that radiotherapy is not contraindicated.

  5. Flavor Models In Extra Dimensions

    CERN Document Server

    Valadez, J

    2005-01-01

    This thesis consists of implementing flavor symmetries in the context of extra dimensions. To the particle content of the Standard Model we add an additional scalar (flavon) field and we assume that all the fields propagate in the extra-dimensional space-time. When the flavon field acquires a vacuum expectation value the flavor symmetry is effectively broken thus generating the Yukawa textures associated with the particles. An specific model in 5D that reproduces all fermion masses, mixing angles and ratios is presented.

  6. Signatures of Large Extra Dimensions

    CERN Document Server

    Hossenfelder, S; Stöcker, H

    2004-01-01

    String theory suggests modifications of our spacetime such as extra dimensions and the existence of a mininal length scale. In models with addidional dimensions, the Planck scale can be lowered to values accessible by future colliders. Effective theories which extend beyond the standart-model by including extra dimensions and a minimal length allow computation of observables and can be used to make testable predictions. Expected effects that arise within these models are the production of gravitons and black holes. Furthermore, the Planck-length is a lower bound to the possible resolution of spacetime which might be reached soon.

  7. CT and Magnetic Resonance Imaging Findings of Psammomatoid Juvenile Ossifying Fibroma of the Middle Turbinate: A Case Report

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sang Kwon; Choe, Mi Sun [Dongsan Medical Center, Keimyung University School of Medicine, Daegu (Korea, Republic of)

    2013-06-15

    Ossifying fibroma of the middle turbinate is extremely rare. We report a case of psammomatoid juvenile ossifying fibroma (PsJOF) of the middle turbinate in an 18-year-old adolescent female along with its CT, MRI and pathologic features. PsJOF of the middle turbinate may present a well-demarcated, expansile, solidly enhancing mass with focal bony destruction, which may mimic various benign and malignant neoplasms of the sinonasal area. A combination of clinical, imaging and pathologic findings is prerequisite for establishing an accurate diagnosis.

  8. Ameloblastic fibroma of the maxilla with bilateral presentation: report of a rare case with review of the literature.

    Science.gov (United States)

    Ealla, Kranti Kiran Reddy; Basavanapalli, Vijayabaskar Reddy; Velidandla, Surekha Reddy; Manikya, Sangameshwar; Ragulakollu, Rajesh; Danappanavar, Prasanna M; Vennila, Vijayasree

    2015-01-01

    Ameloblastic fibroma (AF) is an uncommon benign odontogenic tumour, with both epithelial and mesenchymal neoplastic proliferation. It occurs most frequently in the posterior region of the mandible, while its occurrence in the maxilla is extremely rare. They are usually encountered in children, emphasizing it as an important diagnostic consideration. Herein, we report the first case of a bilateral maxillary ameloblastic fibroma in a 2-year-old female child patient who presented with a chief complaint of swelling in the right mid facial region.

  9. Ameloblastic Fibroma of the Maxilla with Bilateral Presentation: Report of a Rare Case with Review of the Literature

    Directory of Open Access Journals (Sweden)

    Kranti Kiran Reddy Ealla

    2015-01-01

    Full Text Available Ameloblastic fibroma (AF is an uncommon benign odontogenic tumour, with both epithelial and mesenchymal neoplastic proliferation. It occurs most frequently in the posterior region of the mandible, while its occurrence in the maxilla is extremely rare. They are usually encountered in children, emphasizing it as an important diagnostic consideration. Herein, we report the first case of a bilateral maxillary ameloblastic fibroma in a 2-year-old female child patient who presented with a chief complaint of swelling in the right mid facial region.

  10. Cosmology With Dynamical Extra Dimensions

    CERN Document Server

    Erickson, J K

    2005-01-01

    Nearly every attempt to unify the fundamental forces incorporates the idea of compact extra dimensions. The notion was introduced by Kaluza and Klein in the 1920s and is an essential part of contemporary string theory and M-theory. In most treatments the extra dimensions are static. We consider the consequences of extra dimensions with time-varying radii. The radii are modeled by light scalar fields. These may have unusual properties which produce observable effects, such as non-canonical kinetic energies, couplings to matter and radiation, and non- minimal coupling to gravity. Extra dimensions may be responsible for dark energy in the late universe. The simplest model of dark energy is characterized by its equation of state. We show that constraints placed on realistic models by the universality of free fall, variation of fundamental constants and metric tests of gravity are often stricter than bounds on the equation of state. Testing the equivalence principle maybe an effective way of distinguishing some qu...

  11. Wormholes leading to extra dimensions

    CERN Document Server

    Bronnikov, K A

    2016-01-01

    In 6D general relativity with a scalar field as a source of gravity, a new type of static wormhole solutions is presented: such wormholes connect our universe with a small 2D extra subspace with a universe where this extra subspace is large, and the whole space-time is effectively 6-dimensional. We consider manifolds with the structure M0 x M1 x M2 , where M0 is 2D Lorentzian space-time while each of M1 an M2 can be a 2-sphere or a 2-torus. After selecting possible asymptotic behaviors of the metric functions compatible with the field equations, we give two explicit examples of wormhole solutions with spherical symmetry in our space-time and toroidal extra dimensions. In one example, with a massless scalar field (it is a special case of a well-known more general solution), the extra dimensions have a large constant size at the "far end"; the other example contains a nonzero potential $V(\\phi)$ which provides a 6D anti-de Sitter asymptotic, where all spatial dimensions are infinite.

  12. Origin of the 'Extra Entropy'

    Science.gov (United States)

    Mushotzky, R.

    2008-01-01

    I will discuss how one can determine the origin of the 'extra entropy' in groups and clusters and the feedback needed in models of galaxy formation. I will stress the use of x-ray spectroscopy and imaging and the critical value that Con-X has in this regard.

  13. Cosmology with dynamical extra dimensions

    Science.gov (United States)

    Erickson, Joel K.

    Nearly every attempt to unify the fundamental forces incorporates the idea of compact extra dimensions. The notion was introduced by Kaluza and Klein in the 1920s and is an essential part of contemporary string theory and M-theory. In most treatments the extra dimensions are static. We consider the consequences of extra dimensions with time-varying radii. The radii are modeled by light scalar fields. These may have unusual properties which produce observable effects, such as non-canonical kinetic energies, couplings to matter and radiation, and non-minimal coupling to gravity. Extra dimensions may be responsible for dark energy in the late universe. The simplest model of dark energy is characterized by its equation of state. We show that constraints placed on realistic models by the universality of free fall, variation of fundamental constants and metric tests of gravity are often stricter than bounds on the equation of state. Testing the equivalence principle maybe an effective way of distinguishing some quintessence models from a cosmological constant. In certain dark energy models the speed of sound is much less than the speed of light. We calculate how this affects the cosmic microwave background and show that the speed of sound may be measurable, provided dark energy is sufficiently dense at decoupling. This is another possible signature of quintessence. Dynamical extra dimensions may have consequences for the early universe. In the cyclic model, the universe is described in terms of a series of contractions and expansions of an extra dimension. The big bang is preceded by a big crunch and quantum fluctuations of the scalar field produce structure in universe. We consider how the fluctuations evolve and build over many cycles and show that there are no observable instabilities or adverse effects. In the cyclic model extra dimensions act as both dark energy and as an agent to cause contraction and a big crunch. Previous theorems suggested that contraction

  14. Ameloblastic fibrosarcoma of the jaws. A clinicopathologic and DNA analysis of five cases and review of the literature with discussion of its relationship to ameloblastic fibroma.

    Science.gov (United States)

    Muller, S; Parker, D C; Kapadia, S B; Budnick, S D; Barnes, E L

    1995-04-01

    Ameloblastic fibrosarcoma, the malignant counterpart of the ameloblastic fibroma, is a rare odontogenic tumor characterized by benign epithelium and a malignant fibrous stroma. We have compared nuclear DNA content of five ameloblastic fibrosarcomas and three ameloblastic fibromas by image analysis. The three ameloblastic fibromas were diploid, whereas 1 of 5 ameloblastic fibrosarcomas was aneuploid. There was no correlation with histologic grade and aneuploidy. These five new cases were also added to a review of the literature, bringing the total cases of reported ameloblastic fibrosarcomas to 51. The ameloblastic fibrosarcoma occurs at a later age (mean, 27.5 years) compared with reported ameloblastic fibromas (mean, 14.6 to 22 years), which supports a step-wise malignant transformation. There was histologic documentation that 44% of ameloblastic fibrosarcomas developed in ameloblastic fibromas. In view of this data and of the reported cumulative recurrence rate of 18.3% for ameloblastic fibroma, it is recommended that ameloblastic fibromas be treated with complete surgical excision and long-term follow up rather than simple curettage or enucleation.

  15. Fibroma odontogénico maxilar: A propósito de un caso Maxillary odontogenic fibroma: Apropos of a case

    Directory of Open Access Journals (Sweden)

    Oscar N. García-Roco Pérez

    2006-04-01

    Full Text Available El fibroma odontogénico maxilar es un tumor raro, que acontece en menos del 0,1% de los tumores odontógenos. Solo alrededor de 69 casos bien documentados han sido reportados en la literatura. Teniendo en cuenta la casuística, se considera de interés aportar un nuevo caso. Se revisa el tema. Se reporta un caso de paciente masculino, blanco, de 34 años de edad, que refiere inflamación gingival marcada en región de primer molar maxilar derecho que fue diagnosticado clínica, imagenológica e histológicamente en el Hospital Interprovincial Docente Clinicoquirúrgico “Manuel Ascunce Doménech” de Camagüey, e intervenido quirúrgicamente en el año 2002. Se brindan consideraciones diagnósticas y terapéuticas reportadas en la literatura. El paciente en el momento del reporte está rehabilitado y controlado.The maxillary odontogenic fibroma is a rare tumor that appears in less than 0.1 % of the odontogenic tumors. Only about 69 well documented cases have been reported in literature. Taking into account the casuistics, it was considered interesting to report a new case of a white 34-year-old male patient that referred marked gingival inflammation in the region of the first right maxillary molar that was diagnosed from the clinical, imaging and histological point of view at “Manuel Ascunce Doménech” Interprovincial Teaching Hospital, in Camagüey, and was operated on in 2002. Diagnostic and therapeutic considerations reported in literature are given. The patient at the moment of the interview was rehabilitated and under control.

  16. Management of Traumatic Fibroma in a Patient with Cerebral Palsy Using 810nm Diode Laser

    Science.gov (United States)

    Sierra-Garcia, Gerardo Daniel; Nájera, Rosa Isela Sánchez; Perales-Perez, áRaúl Vicente

    2017-01-01

    There are several treatment options for hyperplastic gingival lesions. Among these, diode lasers have the advantages of less bleeding, which is an important characteristic in mucosal lesions, a shorter procedure time, better healing, and less complications. We present the case of a 48-year-old male patient with a history of cerebral palsy and a presumptive diagnosis of traumatic fibroma. The entire lesion was removed in one session with no complications. No recurrence was observed at 3 months follow up. This procedure can be considered a good modality especially for physically challenged patients. PMID:28384984

  17. Cemento-ossifying fibroma of mandible: An unusual case report and review of literature.

    Science.gov (United States)

    Mohapatra, Mounabati; Banushree, C S; Nagarajan, K; Pati, Debashish

    2015-01-01

    The term ossifying fibroma (OF) has recently been included under fibro-osseous lesions. Cemento-OF (COF) is a benign neoplasm that arises from the periodontal membrane which contains multipotential cells that are capable of forming cementum, lamellar bone and fibrous tissue. These tumors occur in the third and fourth decades of life with a predilection for women. The mandible is more commonly involved than the maxilla. This lesion has caused considerable controversy regarding the use of terminology, origin and diagnostic criteria. This article describes an unusual case of COF presenting as unilocular lytic lesion of mandible in a 38-year-old male patient with review of literature.

  18. Peripheral odontogenic fibroma: a rare gingival neoplasm with clinico-pathological differential diagnosis.

    Science.gov (United States)

    Kumar, Rajesh; Jaiswal, Shradha; Sharma, Aanchal; Andhare, Vinod; Sabir, Husain

    2015-01-01

    The peripheral odontogenic fibroma (POdF) is a rare gingival neoplasm, characterised by relatively mature collagenous fibrous tissue and varying amounts of odontogenic epithelium. It can be described as a slow growing, firmly attached, solid and smooth gingival mass which may be present asymptomatically for years, which may cause displacement of adjacent teeth. The purpose of this article is to discuss a case of POdF, occurring in the maxillary anterior region, with detailed clinico-pathological differential diagnosis to clarify characteristic features of various gingival overgrowths to enhance easy identification.

  19. MR findings of desmoplastic fibroma of the spine. A case report

    Energy Technology Data Exchange (ETDEWEB)

    Kong, K.Y.; Kang, H.S.; Jung, H.W.; Kim, J.J.; Lee, C.K. [Seoul National Univ. College of Medicine (Korea, Republic of). Dept. of Radiology

    2000-07-01

    We report on the MR imaging findings in a case of spinal desmoplastic fibroma (DF). DF of the bone is a rare, locally aggressive tumor. It is commonly located in long bones, pelvis or mandible. DF involving the spine is extremely rare and difficult to distinguish from other bony lesions such as giant cell tumor, chordoma and fibrous dysplasia of the spine. This case of DF of the spine showed MR findings similar to those of DF arising in the metaphysis of a long bone.

  20. [Carpal tunnel syndrome and "trigger wrist" revealing a tendinous sheath fibroma].

    Science.gov (United States)

    Benhima, M A; Ait Essi, F; Abkari, I; Najeb, Y; Fikry, T

    2014-02-01

    The tendinous sheath fibroma (TSF) is a rare benign tumor, exceptionally responsible for carpal tunnel syndrome and "trigger" wrist: we found this association less than ten times in the English and French literature. We report the case of a 63-year-old right-handed carpenter who featured a triggering phenomenon of the right wrist during the flexion-extension movements and compression of the median nerve at the carpal tunnel, secondary to a TSF of the flexor digitorum superficialis. The diagnosis was suspected at the sonography and MRI, the tumor was excised and proven histologically to be a TSF. One year later, the patient remained free of symptoms.

  1. Chondromyxoid fibroma of the rib mimics a chondrosarcoma on 18F-FDG PET/CT

    Energy Technology Data Exchange (ETDEWEB)

    Makis, William (Dept. of Nuclear Medicine, Brandon Regional Health Centre, Brandon (Canada)), email: makisw79@yahoo.com; Ciarallo, Anthony; Lisbona, Robert (Dept. of Nuclear Medicine, Royal Victoria Hospital, McGill Univ. Health Centre, Montreal (Canada))

    2011-06-15

    Chondromyxoid fibroma (CMF) is a rare benign bone tumor of chondroid origin that occurs mostly in the metaphyses of long bones. CMF can occasionally mimic a chondrosarcoma on CT, and the literature on the 18F-FDG PET/CT imaging characteristics of CMF tumors is limited. In the presented case, a large histologically proven CMF chest wall mass was initially misinterpreted as a chondrosarcoma. This case highlights a potential pitfall in the PET/CT evaluation of these rare benign bone tumors

  2. A Case of Verruciform Periungual Fibroma%疣状甲周纤维瘤1例

    Institute of Scientific and Technical Information of China (English)

    高爱英; 金新东; 于小兵; 江瑛

    2013-01-01

    A 29-years-old female presented with periungual tumor on the left great toe for 7 years. The pathologic features consist of acanthosis, hyperkeratosis of epidermis, vascular proliferation and proliferation of dermal collagen fibers. Periungual fibroma was diagnosed.%患者女,29岁.左足拇趾的甲根部肿块7年.手术切除术物组织病理示:表皮角化过度,棘层肥厚,真皮胶原纤维和血管增生.诊断:甲周纤维瘤.

  3. Ameloblastic fibroma with ghost cell differentiation and calcification: A unique case report.

    Science.gov (United States)

    Arora, Manpreet; Dave, Aparna; Shetty, Vishwaprakash; Saluja, Pulin

    2015-01-01

    The ameloblastic fibroma (AF) is an uncommon odontogenic tumor that may present an aggressive behavior and may have potential for malignant transformation. Ghost cell differentiation within AF is extremely rare. There are only seven cases in English literature in which ghost cells are found in AF but all these previously reported cases were associated with typical calcifying odontogenic cyst. Here, we present a unique case in 3(1/2)-year-old child with solid lesion which comprised odontogenic epithelium strands, islands, and myxoid ectomesenchyme with focal areas of ghost cell differentiation and calcification associated with neoplastic epithelium.

  4. Successful resection of a primary cardiac fibroma in a neonate: report of a case.

    Science.gov (United States)

    Yan, Xian-Gang; Jia, Bing; Zhu, Bing-Xue; Hu, Xi-Hong

    2014-09-01

    During the fetal-neonatal period, a primary cardiac tumor may be completely asymptomatic and such tumors may be incidentally discovered by echocardiography. A four-hour-old male was diagnosed to have a cardiac tumor by post-natal echocardiography and was observed closely. Surgery was indicated immediately at the 3 week follow-up examination when the tumor was found to have obstructed the right ventricle outflow. The tumor was resected successfully and its histopathology indicated that it was a fibroma. Follow-up echocardiograms and magnetic resonance imaging 5 months postoperatively demonstrated no evidence of any remaining tumor and his RV function was good.

  5. Cemento-ossifying fibroma of mandible: An unusual case report and review of literature

    Directory of Open Access Journals (Sweden)

    Mounabati Mohapatra

    2015-01-01

    Full Text Available The term ossifying fibroma (OF has recently been included under fibro-osseous lesions. Cemento-OF (COF is a benign neoplasm that arises from the periodontal membrane which contains multipotential cells that are capable of forming cementum, lamellar bone and fibrous tissue. These tumors occur in the third and fourth decades of life with a predilection for women. The mandible is more commonly involved than the maxilla. This lesion has caused considerable controversy regarding the use of terminology, origin and diagnostic criteria. This article describes an unusual case of COF presenting as unilocular lytic lesion of mandible in a 38-year-old male patient with review of literature.

  6. [An immunohistochemical study of the proliferating activity of ameloblastic fibroma and ameloblastic fibrosarcoma].

    Science.gov (United States)

    Lu, Y; Takata, T; Wang, L; Zhou, Z; Wu, L; Zhao, M; Nikai, H

    1998-12-01

    Six cases of ameloblastic fibroma (AF) and three cases of ameloblastic fibrosarcoma (AFS) were immunohistochemically investigated with a proliferating cell nuclear antigen (PCNA) monoclone antibody. Data on the PCNA labeling index (LI) of both epithelial and mesenchymal components were analyzed. The results showed that the PCNA LI of mesenchymal component of AFS (40.8%) was significantly higher than that of AF (3.2%) (P < 0.01) and that of the epithelial component of AFS (5.3%) was significantly lower than that of the mesenchymal one of AFS (P < 0.01). The results suggested that PCNA LI be a useful marker for the differentiation diagnosis of AF and AFS.

  7. Fibroma ameloblástico. Reporte de un caso clínico

    Directory of Open Access Journals (Sweden)

    Gustavo Guzmán

    2013-10-01

    Full Text Available Title: Ameloblastic fibroma. Report of a case report.ResumenEl fibroma ameloblástico (FA es un tumor benigno odontogénico mixto (estroma fibroso y epitelial de rara aparición, que constituye el 2% de todos los tumores odontogénicos. Se caracteriza por presentarse en pacientes jóvenes entre la primera y segunda década de la vida, sin predilección por el sexo y con tendencia de aparición en la mandíbula. Su tratamiento es variado, ya que el mismo va a depender del tamaño de la lesión, de la evolución, de la localización, de la expansión de tablas óseas y del compromiso de tejidos adyacentes; con la finalidad siempre de obtener menor índice de recurrencia, secuelas y complicaciones; por último darle la mayor estética posible al paciente. El objetivo de esta presentación es describir un caso clínico de este tumor, hacer una breve revisión de la literatura y sus diagnósticos diferenciales, analizar sus características clínicas e histológicas y la actitud terapéutica a tomar. (DUAZARY 2012 No. 1, 75 - 81AbstractAmeloblastic fibroma (AF is a benign mixed odontogenic tumor (fibrous stroma and epithelial, a rare occurrence that constitutes 2% of all odontogenic tumors. It is characterized by younger patients between the first and second decades of life, with out predilection for sex with a tendency of appearance in the jaw. Concerning the treatment is varied as it will depend on the size of the lesion, evolution, location, expansion boards and commitment of bone adjacent tissues in order to obtain always slower rate of recurrence, sequelae and complications, and finally give the more aesthetically pleasing to the patient. The objective of this presentation is to describe a case of this tumor, a brief review of the literature and differential diagnosis, analyze their clinical and histological characteristics and therapeutic attitude to take.Key words: Tumor; ameloblastic fibroma; differential diagnosis; hemimandibulectomy.

  8. Ameloblastic fibroma with ghost cell differentiation and calcification: A unique case report

    Directory of Open Access Journals (Sweden)

    Manpreet Arora

    2015-01-01

    Full Text Available The ameloblastic fibroma (AF is an uncommon odontogenic tumor that may present an aggressive behavior and may have potential for malignant transformation. Ghost cell differentiation within AF is extremely rare. There are only seven cases in English literature in which ghost cells are found in AF but all these previously reported cases were associated with typical calcifying odontogenic cyst. Here, we present a unique case in 31/2-year-old child with solid lesion which comprised odontogenic epithelium strands, islands, and myxoid ectomesenchyme with focal areas of ghost cell differentiation and calcification associated with neoplastic epithelium.

  9. Left ventricular cardiac fibroma in a child presenting with ventricular tachycardia.

    Science.gov (United States)

    Stratemann, Stacy; Dzurik, Yvette; Fish, Frank; Parra, David

    2008-01-01

    Cardiac tumors in children are rare. Although most are histologically benign, they can be associated with life-threatening arrhythmias and sudden death. We report a 7-year-old boy, with a first episode of symptomatic tachycardia, who was found to have a left ventricular (LV) fibroma. He had a normal echocardiogram prior to an electrophysiology study, which revealed a sustained monomorphic ventricular tachycardia and a radio-opacity near the LV apex. These findings prompted a cardiac MRI, which demonstrated a discrete mass on his LV apex and free wall. Our case emphasizes that structural heart disease should be aggressively pursued in children presenting with ventricular tachycardia.

  10. A rare case of giant cell fibroma in a pediatric patient

    Directory of Open Access Journals (Sweden)

    Sangeeta Rajesh Patankar

    2016-01-01

    Full Text Available Fibrous hyperplastic lesions are frequently encountered in the oral cavity. Although clinically similar, these lesions show variations histologically. Giant cell fibroma (GCF is one such nonneoplastic fibrous lesion with a characteristic histopathological feature of stellate-shaped multinuclear or mononuclear fibroblasts known as giant cell fibroblasts. In the recent years, more and more GCF cases have been reported in pediatric patients. This case report describes a papillary soft tissue growth in the lower right posterior region of the mandible in a 5-year-old child with a review on giant cell fibroblasts.

  11. Fibroma osificante de mandíbula: presentación de un caso y revisión de la literatura Mandibular ossifying fibroma: case report and literature review

    Directory of Open Access Journals (Sweden)

    A. Lombardi

    2009-08-01

    Full Text Available Dentro de las lesiones fibro-óseas benignas se encuentra el fibroma osificante (FO; esta entidad se considera una verdadera neoplasia que comprende una proliferación encapsulada de tejido fibroso; que afecta generalmente a los maxilares especialmente a la mandíbula en la región de molares. Su crecimiento es lento, pudiendo generar el desplazamiento dentario, incluso la rizólisis de los mismos. Para el diagnóstico de FO se requiere de la correlación clínica-radiológica, con los hallazgos intraoperatorios; ya que la histología puede presentar similitudes con otras lesiones fibro-óseas. Se describe el caso de un paciente tratado en nuestro servicio por fibroma osificante de maxilar inferior.The benign fibro-osseous lesions include ossifying fibroma (OF. This condition is considered to be a true neoplasm consisting of an encapsulated proliferation of fibrous tissue that generally affects the jaws, especially the molar region of the mandible. Its growth is slow and it can cause tooth displacement, including dental rhizolysis. In order to reach the diagnosis of OF, a clinico-radiologic correlation with intraoperative findings is required because the histology may be similar to other fibro-osseous lesions. The case of a patient treated in our department for ossifying fibroma of the mandible is reported.

  12. Congenital peripheral ameloblastic fibroma with intraosseous involvement in a 2-week-old infant: A case report with review of literature.

    Science.gov (United States)

    Langer, Sabina; Choudhury, Monisha; Agarwal, Savita; Mehra, Parvesh

    2015-01-01

    Ameloblastic fibroma is a rare, slow-growing benign mixed odontogenic tumor. It constitutes 2% of odontogenic tumors and is reported to occur at an age ranging from 6 months to 42 years. The youngest being a 7-week-old infant. We report a case of peripheral ameloblastic fibroma in a 2-week-old infant. The lesion presented since birth. It involved the maxilla with an extraosseous component involving the gingiva. A more or less conservative surgical approach of enucleation and curettage of the lesion was done under general anesthesia, trying to conserve the adjacent tooth buds. Only a few cases of congenital peripheral ameloblastic fibroma have been reported so far.

  13. Mitotically active cellular fibroma of ovary should be differentiated from fibrosarcoma: a case report and review of literature.

    Science.gov (United States)

    Zong, Lin; Lin, Ming; Fan, Xinmin

    2014-01-01

    The clinicopathologic characteristic of mitotically active cellular fibroma is significantly different from the malignant behavior of ovarian fibrosarcoma. Therefore, it's very important to differentiate mitotically active cellular fibroma from ovarian fibrosarcoma. We report a case in which a 39-year-old woman was found with an ovarian tumor measuring 105 × 71 × 47 mm. The tumor ruptured and adhered to the peritoneum. Microscopic examination showed densely cellular spindle-shaped tumor cells. The cellular atypia was mild. The Ki-67 proliferation index was approximately 10%. The patient remained free of tumor for more than 66 months without any adjuvant chemotherapy after operation. After reviewing the literature, we diagnosed this case as mitotically active cellular fibroma rather than ovarian fibrosarcoma. It is very important to differentiate these two tumors because of the marked differences in treatment modalities and prognosis between them. The ovarian fibrous tumors with mitotic figures ≥ 4 per 10 high-power fields but no severe nuclear atypia should be mostly diagnosed as mitotically active cellular fibroma of ovary. The correct diagnosis is the key to avoid excessive treatments.

  14. Nevoid basal cell carcinoma syndrome with a unilateral giant ovarian fibroma in a Japanese 6-year-old girl.

    Science.gov (United States)

    Jimbo, Takahiro; Masumoto, Kouji; Urita, Yasuhisa; Takayasu, Hajime; Shinkai, Toko; Uesugi, Toru; Gotoh, Chikashi; Sakamoto, Naoya; Sasaki, Takato; Oto, Tatsuyuki; Fukushima, Takashi; Noguchi, Emiko; Nakano, Yoshiro

    2014-05-01

    Nevoid basal cell carcinoma syndrome (NBCCS) is characterized by basal cell carcinoma, skeletal abnormalities, benign tumors including ovarian fibroma, and various other phenotypic expressions. Ovarian fibromas in NBCCS before puberty are very rare. We report a 6-year-old prepubescent girl with NBCCS showing skeletal abnormalities, medulloblastoma, and ovarian fibromas. The patient was referred to our hospital owing to abdominal distension. On admission, a huge elastic hard tumor was palpable and computed tomography showed a huge tumor of the left ovary. We performed a left salpingo-oophorectomy and diagnosed the tumor as a benign fibroma. Further examination of the computed tomography images showed skeletal abnormalities. In addition, the patient had a history of medulloblastoma at the age of 4 years. Therefore, we diagnosed NBCCS. A genetic examination indicated a novel 1 bp deletion in exon 18 (c.3055delG). Sequence analysis of exon 18 using DNA from the ovarian tumor revealed a mutant allele (c.3055delG) dominant to the wild-type allele, thus suggesting loss of heterozygosity in the PTCH1 gene, which is known to be associated with NBCCS. Conclusion On the basis of our experience, physicians treating pediatric ovarian tumors should be aware that such huge benign ovarian tumors may be a phenotype of NBCCS, as shown in our patient. In addition, genetic examination focusing on the PTCH1 gene might be important for diagnosis of NBCCS in pediatric patients.

  15. Gorlin syndrome presenting with a unilateral ovarian fibroma in a 22-year-old woman: a case report

    Directory of Open Access Journals (Sweden)

    Finch Terence

    2012-06-01

    Full Text Available Abstract Introduction Nevoid basal cell carcinoma syndrome, or Gorlin syndrome, is an inherited disorder characterized by malignancies of the skin and other organs, skeletal abnormalities, and congenital malformations. The syndrome follows an autosomal dominant inheritance pattern with a gene mutation localized to 9q22.3. Case presentation We present the case of a 22-year-old Caucasian woman with a unilateral ovarian fibroma, falx cerebri calcification and odontogenic keratocysts, but without any skin manifestations. The diagnosis of nevoid basal cell carcinoma syndrome was made after a right salpingo-oophorectomy for a calcified ovarian fibroma with cystic degeneration. Pathologic examination of the 10 cm right ovarian mass revealed a well-circumscribed spindle cell lesion. Immunohistochemical staining of the lesion demonstrated positivity for vimentin and smooth muscle actin. Conclusion It is important to recognize that nevoid basal cell carcinoma syndrome may present in the absence of skin lesions. Additionally, ovarian fibromas are typically bilateral in nevoid basal cell carcinoma syndrome, but can uncommonly be unilateral, which may alter clinical management. Ovarian fibromas are managed with surgical excision with an attempt at ovarian functional preservation.

  16. Search for extra space dimensions with ATLAS

    Indian Academy of Sciences (India)

    Ambreesh Gupta; ATLAS Collaboration

    2004-03-01

    If extra spatial dimensions were to exist, they could provide a solution to the hierarchy problem. The studies done by the ATLAS Collaboration on the sensitivity of the detector to various extra dimension models are reported in this document.

  17. Fibroma desmoplásico de maxilar en paciente pediátrico: Reporte de caso

    Directory of Open Access Journals (Sweden)

    Roberto Gerber Mora

    2015-07-01

    Full Text Available La presencia de tumefacciones en la cavidad bucal del paciente pediátrico puede ser indicativo de gran cantidad de patologías y enfermedades sistémicas, algunas incluso pueden perjudicar el bienestar del mismo. El Fibroma desmoplásico es un tumor óseo benigno, localmente destructivo, catalogado como muy poco frecuente. Se reporta el caso de un niño de 4 años con fibroma desmoplásico en el maxilar de alrededor de 2 años de evolución, observándose como una tumefacción generalizada del segundo cuadrante, con ausencia de signos y síntomas de inflamación. Por su edad representa un reto para el clínico ya que el abordaje debe ser interdisciplinario con profesionales expertos en odontopediatría, cirugía y patología. Se describe a profundidad cada paso del proceso diagnóstico incluyendo hallazgos clínicos, radiográficos e histológicos, así como la toma de la muestra para su estudio.

  18. Psammomatoid variant of juvenile ossifying fibroma involving mandible: A rare case report

    Directory of Open Access Journals (Sweden)

    Saurabh Kumar

    2015-01-01

    Full Text Available The term juvenile ossifying fibroma (JOF is used in literature in naming two microscopically distinct fibro-osseous lesions of the craniofacial skeleton. One is characterized by small uniform spherical ossicles resembling psammoma bodies (psammomatoid JOF [PsJOF]. The other is distinguished by trabeculae of fibrillary osteoid and woven bone (trabecular JOF. Psammomatoid ossifying fibromas represent a unique subset of fibro-osseous lesions of the craniofacial region. PsJOF has been distinguished because of its location, clinical behavior, and age of occurrence. They have distinctive histomorphologic features and a tendency toward locally aggressive behavior, including invasion and destruction of adjacent anatomic structures. It is generally seen in the younger age group, and the most common site is paranasal sinuses, orbits, and frontoethmoidal complex. We report a case of JPOF involving mandible which is rarely been described in literature. An insight into the radiographic progression of this rare entity along with the clinical feature and surgical management is discussed.

  19. Ameloblastic fibroma: A rare case appearing as a mixed radiographic image.

    Science.gov (United States)

    de Castro, Jurema-Freire-Lisboa; Correia, Andreza-Veruska-Lira; Santos, Lucas-Alexandre-Moraes; Guerra, Luiz-Antônio-Portela; Ramos-Perez, Flávia-Maria-de-Moraes; Perez, Danyel-Elias-da Cruz

    2014-12-01

    Ameloblastic fibroma (AF) is a benign tumor of mixed odontogenic origin, which affects predominantly young individuals. AF appearing as a mixed radiographic image is very rare. This report describes a case of AF in a 12-year-old male identified during a routine radiographic exam for orthodontic treatment planning. The panoramic radiography revealed a well-defined multilocular mixed image located in the mandible between the roots of the left mandibular second premolar and first molar. The lesion was excised under local anesthesia. Histopathological analysis revealed islands of epithelial cells and columnar peripheral cells showing a nucleus in inverted polarization, interspersed with spindle-shaped cells and abundant extracellular matrix deposition. No atypia was observed. The diagnosis of AF was established. No tumor recurred up to 30 months after treatment. Although rare, AF should be also considered in the differential diagnosis of mixed radiographic images of the jaws in young patients. Key words:Ameloblastic fibroma, differential diagnosis, incidental finding, mixed image, radiographic features.

  20. Central ossifying fibroma, periapical cemento-osseous dysplasia and complex odontoma occurring in the same jaw

    Directory of Open Access Journals (Sweden)

    Farzaneh Agha Hosseini

    2011-05-01

    Full Text Available Central ossifying fibroma is a rare, benign fibro-osseous lesion that arises from the periodontal ligament. Periapical cemento-osseous dysplasia is another variant of fibro-osseous lesion which occurs in the anterior region of the mandible of females. Odontoma is a benign odontogenic tumor that contains enamel, dentine cement and pulp tissue. A 46-year-old woman was referred to the Department of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, with two nonpainful swellings on both sides of the mandible, which had been slowly growing over a period of one year. Our differential diagnosis was florid cemento-osseous dysplasia, focal cemento-osseous dysplasia for the right side, complex odontoma for the left side and periapical cement-osseous dysplasia for the anterior side. The historical feature revealed ossifying fibroma, complex odontoma and periapical cemento-osseous dysplasia. The occurrence of these three lesions in the same jaw has been rarely reported in the literature. The relationship between the occurrence of these three lesions is not obvious it could be coincidental. It seems that more case reports are needed to establish the relationship between them.

  1. Light Stops from extra dimensions

    CERN Document Server

    Garcia-Pepin, Mateo

    2016-01-01

    In supersymmetric models the mass of the stops can be considered as the naturalness measure of the theory. Roughly, the lighter the stops are, the more natural the theory is. Both, the absence of supersymmetric signals at experiment and the measurement of the Higgs mass, put scenarios with light stops under increasing tension. I will present a supersymmetry breaking mechanism of the Scherk-Schwarz type that, by introducing extra $SU(2)_L$ triplets in the Higgs sector, is able to generate the correct Higgs mass while keeping stops light.

  2. Somatic copy number losses on chromosome 9q21.33q22.33 encompassing the PTCH1 loci associated with cardiac fibroma.

    Science.gov (United States)

    Zhang, Qianqian; Wang, Tongjian; Wang, Dong; Liu, Jinxiu; Yu, Wenqian; Liu, Xiangju; Xiang, Xiaoli; Dong, Kai; You, Feng; Zhang, Guichun; Ju, Jifeng; Zhu, Meng; Duan, Wenyuan; Qiao, Bin

    2015-12-01

    Cardiac fibroma is an extremely rare benign tumor that remains poorly characterized genetically. Somatic copy number alterations are common in tumors and have been defined as a crucial factor leading to tumors. In this study, we present a child diagnosed with cardiac fibroma with somatic copy number losses of a total of three discontinuous segments from 9q21.33 to 9q22.33, including a mosaic deletion of PTCH1. PTCH1 has been associated with sporadic cardiac fibroma. Sequencing analysis of the PTCH1 gene has not revealed any causative mutation. Quantitative PCR analysis of PTCH1 further confirms somatic copy number losses. Our data narrow down the critical causative deletions for sporadic cardiac fibroma to a region more precise than any other previously reported one. Our results suggest important roles of somatic copy number losses on chromosome 9q21.33q22.33 in the development of sporadic cardiac fibroma; these findings may provide a better understanding of sporadic cardiac fibroma pathogenesis and contribute to the identification of novel diagnostic biomarkers of this neoplasm. .

  3. Higgs Bosons in Extra Dimensions

    CERN Document Server

    Quiros, Mariano

    2015-01-01

    In this paper, motivated by the recent discovery of a Higgs-like boson at the LHC with a mass m_H\\simeq 126 GeV, we review different models where the hierarchy problem is solved by means of a warped extra dimension. In the Randall-Sundrum model electroweak observables provide very strong bounds on the mass of KK modes which motivates extensions to overcome this problem. Two extensions are briefly discussed. One particular extension is based on the deformation of the metric such that it strongly departs from the AdS_5 structure in the IR region while it goes asymptotically to AdS_5 in the UV brane. This model has the IR brane close to a naked metric singularity (which is outside the physical interval) characteristic of soft-walls constructions. The proximity of the singularity provides a strong wave-function renormalization for the Higgs field which suppresses the T and S parameters. The second class of considered extensions are based on the introduction of an extra gauge group in the bulk such that the custod...

  4. A UNIQUE STAR SHAPED PERIPHERAL OSSIFYING FIBROMA MIMICKING ORAL CARCINOMA : A RARE CASE REPORT

    Directory of Open Access Journals (Sweden)

    Pallavi Pandey

    2013-07-01

    Full Text Available Introduction: The gingiva is often the site of localized growths that areconsidered to be reactive rather than neoplastic in nature. Peripheral ossifying fibromais one such reactive lesion. This case report documents a case of a 15-year-old girl witha large peripheral ossifying fibroma in the posterior maxilla showing significantgrowth and interference with occlusion. Methods: Review of literature concerningetiology, pathogenesis and management of the resulting gingival enlargement isdiscussed. Conclusion: Many of these lesions are difficult to be identified clinicallyand can be identified as specific entity only on the basis of typical and consistenthistomorphology. Surgical treatment of the POF in adolescents should be initiatedsoon, given the high recurrence rate, because although gingival enlargement thatoccurs can be treated, the alveolar bone loss is irreversible, compromising toothsupporting apparatus permanently.

  5. Chondromyxoid fibroma of the femur in a child aged 9 years (Clinical case

    Directory of Open Access Journals (Sweden)

    Александр Павлович Поздеев

    2015-09-01

    Full Text Available The article reflects the experience in the diagnosis and surgical treatment of chondromyxoid fibroma in the proximal metadiaphysis of a large femoral bone in a child in the first decade of life. We presented the family and medical history of the child complaints, orthopedic/local status, and the results of radiological methods and emphasized difficulties of nosologic identification and differential diagnosis of the bone destructive process at the stage before biopsy and surgery. Macroscopic findings during surgery were identified, and the amount of resection of the affected bone was determined. A detailed description of the results of pathological and morphological (macro- and microscopic studies is given, which could confirm the tumor process. Late results with the absence of oncological re-occurrence (7 years and good anatomical and functional results from orthopedic surgery are shown.

  6. Sclerotic fibroma (storiform collagenoma)-like stroma in a fibroadenoma of axillary accessory breast tissue.

    Science.gov (United States)

    Val-Bernal, José Fernando; González-Vela, María Carmen; De Grado, Mauricio; Garijo, María Francisca

    2012-08-01

    Accessory breast tissue is a subcutaneous remnant persisting after normal embryological development of the breast. It occurs most frequently in the axilla. Fibroadenomas in axillary breast tissue are rare. We report the case of a 29-year-old female patient who presented a fibroadenoma arising in the accessory breast tissue of the right axillary fossa. The neoplasm showed foci of sclerotic fibroma-like stroma. The patient had no signs of Cowden's syndrome. To the best of our knowledge, a lesion of this kind has not been previously reported. This stromal change suggests an uncommon involutional phase of the fibroadenoma with production of sclerotic and hypocellular collagen. The lesion should be differentiated from extraneural perineuroma, from the changes in fibroadenomas in Cowden's syndrome, from sclerosing lobular hyperplasia (fibroadenomatoid mastopathy) and from pseudoangiomatous stromal hyperplasia.

  7. Reconstruction of maxillary cemento-ossifying fibroma defect with buccal pad of fat.

    Science.gov (United States)

    Sivaraj, Subramonian; Jeevadhas, Pratheep

    2013-07-01

    A cemento-ossifying fibroma (COF) is a rare benign neoplasm of maxilla when compared with mandible (World Health Organization, 1992). COF of maxilla may be quite large and locally very aggressive lesion. These tumor mass was peeled out by en-bloc excision using gentle blunt dissection. This paper presents 35-year-old male patient who had a gradually expanding lobular mass in the left maxillary posterior region for past 1 year. He has been treated successfully by surgical en-bloc resection. Various techniques were used to reconstruction the defect. Buccal pad of fat is a simple technique having advantages like good vascularity, adaptability, good closure of the defect with favorable prognosis.

  8. Peripheral cemento-ossifying fibroma: A case report with review of literature.

    Science.gov (United States)

    Mishra, Amit Kumar; Maru, Rahul; Dhodapkar, Shrikant Vishnuprasad; Jaiswal, Gagan; Kumar, Rajesh; Punjabi, Heena

    2013-06-16

    Peripheral cemento-ossifying fibroma (PCOF) is a rare osteogenic neoplasm that ordinarily presents as an epulis-like growth. This is of a reactive rather than neoplastic nature and its pathogenesis is uncertain. PCOF predominantly affects adolescent and young adults with greatest prevalence around 28 years. We report here a rare clinical case of PCOF of the mandible, 1 cm mesiodistally and 1.5 cm occluso-gingivally in diameter, which caused difficulty in eating and speech, in a 42-year-old female patient. She was asymptomatic for 1 year and on follow-up for 6 mo post surgically showed gingival health and normal radioopacity of bone without any recurrence. Clinical, radiographic and histological characteristics are discussed and recommendations regarding differential diagnosis, treatment and follow up are provided. The controversial varied nomenclature and possible etiopathogenesis of PCOF are emphasized.

  9. Cases report of ossifying fibroma showing various radiographic appearances in posterior mandible

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Byung Do; Oh, Seung Hwan [School of Dentistry, Wonkwang University, Seoul (Korea, Republic of); Son, Hyun Jin [Department of Pathology, School of Medicine, Eulji University, Daejeon (Korea, Republic of)

    2010-06-15

    Common radiographic appearances of ossifying fibroma (OF) are well demarcated margin, radiolucent or mixed lesion. Lesions for the radiographic differential diagnosis with OF include fibrous dysplasia, focal cemento-osseous dysplasia. Other confusing lesions might be the mixed lesions such as calcifying odontogenic cyst, adenomatoid odontogenic tumor, calcifying epithelial odontogenic tumor, and benign cementoblastoma. We reported three cases of OF in posterior mandible. These cases showed a little distinguished radiographic features of OF and diagnosed from a combination of clinical, radiographic, and histopathologic information. We need to further refine radiographic and histopathological features of OF and other confusing lesions with literatures review because some cases of these lesions are not easily differentiated radiographically and histopathologically.

  10. Recurrent multicentric peripheral ossifying fibroma-like lesion in a child: a case report.

    Science.gov (United States)

    Lima, Marina Deus Moura; Teixeira, Rubens G; Bonecker, Marcelo; de Camargo Moraes, Paulo; Mantesso, Andrea

    2014-09-25

    Gingival hyperplasias are peculiar conditions that may produce extreme growth that impairs masticatory function and causes psychological and aesthetic disturbances. They can vary from mild interdental papillae localized growth to marked swelling affecting both jaws. The aim of this case report is to present a rare case of generalized gingival growth diagnosed in a 4 year-old Caucasian child and followed for 9 years. The lesion covered almost all of the upper and lower teeth and recurred thirty times with the same clinical and histopathological aspects. The clinical features suggested the diagnosis of idiopathic gingival fibromatosis, but the histopathological aspects did not confirm this hypothesis and were consistent with peripheral ossifying fibroma. The present case reports a rare gingival growth with challenging diagnosis and treatment.

  11. Psammomatoid juvenile ossifying fibroma of mandible in a 6-year-old child

    Science.gov (United States)

    Manjunatha, B. S.; Purohit, Sharad; Kiran, Sheetal; Mahita, V. Naga

    2016-01-01

    Juvenile ossifying fibroma (JOF) is a rare fibro-osseous lesion of the jaw occurs at the early age of onset frequently under 15 years with a propensity to recur. It appears as a unilobulated/multilobulated lesion at an early stage followed by radiopaque appearance surrounded by radiolucent rimming at advanced stages. The psammomatous type of JOF (PsJOF) principally involves the bones of the orbit and paranasal sinuses. However in some cases, maxilla or rarely the mandible may be pretentious. Here, we report a challenging case of PsJOF in a 6-year-old child with a complaint of swelling imitating a cystic lesion in left back region of the lower jaw for 2 months. The authors propose that a careful examination and correlations of clinical, radiological, and histopathological features are essential to arrive at correct diagnosis and play a vital role in management of such patients. PMID:27134454

  12. Central Odontogenic Fibroma (WHO Type: A Case Report and Review of Literature

    Directory of Open Access Journals (Sweden)

    Subrata Talukder

    2011-01-01

    Full Text Available We report a case of 15-year-old boy presented with painless swelling of right side of lower jaw since 2 years. A provisional diagnosis of dentigerous cyst involving an impacted lower second premolar was concluded after clinical examination. Radiographs revealed an expanding, well demarcated radiolucency with thin, fine, straight septae, causing root resorption and displacement of adjacent teeth and the impacted tooth was pushed to the interior border of mandible. Histologically pronounced fibroblastic hypercellularity with epithelial rests and focal areas with dentinoid or cementoid material was seen, suggestive of Central Odontogenic Fibroma (WHO Type. Only eight such cases have been reported in English literature and present one is 9th case.

  13. Case report of an oral fibroma occurring in a patient with familial multiple lipomas.

    Science.gov (United States)

    Radfar, Lida; Holt, Tyler; Masood, Farah

    2013-12-01

    A wide variety of lesions may manifest in the oral soft tissues that could be confusing and challenging for the clinicians. These lesions could be as simple as trauma-induced ulcers that need about 2 weeks to heal, to a more complicated situation such as oral cancer. The key points in developing diagnosis and a possible treatment plan may include a comprehensive oral examination, simple understanding of normal oral tissue features, and knowledge of common oral lesions. This will help in the development of a differential diagnosis of the oral lesions/masses based on the risk factors in that particular patient. In this case report, we present a simple oral mass in a patient who had an oral fibroma and lipomas in other areas.

  14. Cystic Endometrioma with Coexisting Fibroma Originating in a Supernumerary Ovary in the Rectovaginal Pouch

    Science.gov (United States)

    Sakaguchi, Asumi; Kodama, Hiroko; Ogura, Kanako; Miwa, Ayako; Sugimori, Yayoi; Matuoka, Shozo; Matsumoto, Toshiharu

    2017-01-01

    A supernumerary ovary is an exceedingly rare disorder, in which the structure containing ovarian tissue is located at some distance from the normally placed ovary. 16 cases of endometriosis or tumors originating in a supernumerary ovary have been published in the English literature, but no case of coexisting endometriosis and a tumor has been published. We present the case of a 40-year-old female with cystic endometrioma with coexisting fibroma originating in a supernumerary ovary in the rectovaginal pouch. The present case is the first to be reported with coexisting endometriosis and a tumor originating in a supernumerary ovary. Our experience with this case and the results of our previous studies of rectovaginal endometriosis indicated that the possibility of originating in a supernumerary ovary shall be examined in cases of cystic endometrioma in the rectovaginal pouch. PMID:28210515

  15. Cardiac Fibroma in a Neonate Presenting With Dyspnea and Tachycardia: A Very Rare Case Tachycardia

    Directory of Open Access Journals (Sweden)

    Anvari Shahriar

    2016-01-01

    Full Text Available Introduction: Cardiac tumors can be divided to primary and secondary and to benign and malignant tumors. One of the benign tumors of the heart is cardiac fibroma. More than 80% of this tumor occurs in children; however its occurrence in neonates is very rare. Fewer than 100 cases have been reported. Case Presentation: Our patient is a 10 day’s girl neonate with severe dyspnea, mild cyanosis, tachycardia (heart rate = 170- 180/min and obstruction of right ventricle (RV outlet with very large tumor. Conclusion: Cardiac tumors in neonate population must be considered in the diagnosis of arrhythmias, cardiac insufficiency, valvular disease, cardiomegaly or presence of murmurs. Early diagnosis before birth should be appropriate and accurate imaging devices must be used in detecting these tumors.

  16. Chondromyxoid fibroma of the pubic ramus: a case report and literature review.

    Science.gov (United States)

    Arıkan, Murat; Toğral, Güray; Yıldırım, Ahmet; Aktaş, Erdem

    2016-01-01

    Chondromyxoid fibromas (CMF) are benign cartilaginous bone tumors which are found most frequently in the metaphyses of long bones. They comprise less than 1% of primary bone neoplasms. We report an interesting incidental case of a 43-year-old woman with a CMF of the left pubic ramus, presenting with complaints of gradual onset of left groin pain over a period of 2 years. According to radiological examination, a malign chondroid bone tumor was excluded, and histopathological examination confirmed the diagnosis of CMF. The patient underwent aggressive curettage and bone grafting 6 years ago. Pelvic bones are encountered as rare localizations for CMFs. Pubic ramus is accepted as an exceptional site for this benign bone tumor of cartilaginous origin. To our knowledge, no any other CMF case in this localization has been reported in the literature. In atypical regions such as the pelvis and pubic ramus, CMF must be considered for differential diagnosis of malign tumors.

  17. Stromal Overgrowth in a Brenner Tumor or Ovarian Fibroma With Minor Sex Cord Elements?

    Science.gov (United States)

    Ross, Julia A; Saglam, Ozlen

    2015-07-01

    Computed tomography obtained as part of a urinary tract assessment in a 68-year-old woman incidentally detected a solid adnexal mass. Bilateral salpingo-oophorectomy revealed a unilateral, 4-cm, white to tan-yellow colored, focally calcified, left ovarian mass. Microscopically, the tumor was composed of bland fibroblasts, abundant collagen, and areas of calcification with a minor component composed of nests of epithelial cells with nuclear clefts focally evident, some of which contained central lumens with eosinophilic secretions. The major considerations were fibromatous overgrowth in a Brenner tumor or ovarian fibroma with minor sex cord elements. Immunostains for cytokeratin 7 showed diffuse positivity in the epithelial nests, whereas cytokeratin 20 and inhibin were negative, further supporting the diagnosis of a Brenner tumor.

  18. Ameloblastic fibroma of the mandible associated with root resorption and unerupted teeth: a case report.

    Science.gov (United States)

    Dimitrakopoulos, Ioannis; Psomaderis, Konstantinos; Zaramboukas, Thomas

    2008-06-01

    Ameloblastic fibroma (AF) is an uncommon benign odontogenic mixed tumor. A case of an AF associated with unerupted and missing teeth is presented. A 13-year-old girl was referred for evaluation of a painless swelling of her right mandible. The most remarkable finding was the resorption of the proximal root of the permanent first molar. The lesion was completely enucleated. Follow-up showed satisfactory bony healing, and the resorbed root was completely surrounded by a continuous layer of intact lamina dura. In most cases, the patient presents to the clinician complaining of an unerupted tooth at the posterior area of the mandible. The most remarkable finding in our case, however, was the coexisting root resorption. This finding could indicate a more aggressive form of AF. AF has a very good prognosis. Malignant transformation is extremely rare.

  19. Argyrophilic nucleolar organizer regions (AgNORs) in odontogenic myxoma (OM) and ameloblastic fibroma (AF).

    Science.gov (United States)

    Martins, C; Carvalho, Y R; do Carmo, M A

    2001-09-01

    Ten cases of odontogenic myxoma (OM) and six cases of ameloblastic fibroma (AF) were subjected to comparative analysis by the AgNOR technique, in order to determine a possible difference in cell proliferation index between these lesions. The mean AgNOR number of the mesenchymal component of AF was compared with its epithelial component and the difference was not found to be statistically significant. The mean AgNOR index of the AF group was significantly higher than that of the OM group. Moreover, the mesenchymal component of AF demonstrated increased AgNOR numbers compared with that of OM (P<0.05). These results suggest that the epithelial and mesenchymal components of AF may have similar cell proliferative activity. However, the cell proliferative index of this lesion seems to be higher than that of OM.

  20. Rapid sarcomatous transformation of an ameloblastic fibroma of the mandible: case report and literature review.

    Science.gov (United States)

    Kousar, Aisha; Hosein, Mervyn M; Ahmed, Zubair; Minhas, Khurram

    2009-09-01

    Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumour regarded as the malignant counterpart of ameloblastic fibroma. It is characterized by a benign epithelial component within a malignant fibrous stroma. AFS is a locally aggressive neoplasm with extremely low potential for metastasis. We report an extremely rare, rapidly progressive, and fatal case originating in the posterior mandible of a 20-year old female patient. Initially histopathologically diagnosed as a benign lesion, it rapidly recurred with apparent transformation into a high-grade sarcoma over a period of 6 months. Subsequent intracranial and pulmonary metastases were noted, and the patient died within 15 months of initial consultation. This case emphasizes the need for a high element of suspicion about clinically ambiguous lesions. We recommend more extensive or radical, primary excisions in lesions that have a known potential for recurrence or malignancy.

  1. Radiotherapy for juvenile ossifying fibroma of the maxillary sinus: Case report and literature review.

    Science.gov (United States)

    Strickler, Scott; Hitchcock, Kathryn E; Dziegielewski, Peter T; Mendenhall, William M

    2017-08-01

    Juvenile ossifying fibroma (JOF) is a benign fibro-osseous lesion that can be locally aggressive. It is typically treated with surgical excision. A few cases using adjuvant radiotherapy have been reported in the literature. We report a case of JOF treated with surgical excision and adjuvant radiotherapy to minimize the risk of local recurrence. We also review the literature. Our patient tolerated radiotherapy without complication and had not experienced a local recurrence at the time of writing this manuscript. This is one of the first reports of adjuvant radiotherapy after surgical excision to improve local control in patients with JOF. Radiotherapy should be considered in patients for whom reexcision after a recurrence would result in unacceptable morbidity. © 2017 Wiley Periodicals, Inc.

  2. Flavor Symmetries in Extra Dimensions

    CERN Document Server

    Aranda, A; Aranda, Alfredo

    2002-01-01

    We present a model of flavor based on a discrete local symmetry that reproduces all fermion masses and mixing angles both in the quark and lepton sectors. The particle content of the model is that of the standard model plus an additional flavon field. All the fields propagate in a fifth universal extra dimension and the flavor scale is associated with the cutoff of the 5D theory which is $\\sim 10$ TeV. The Yukawa matrices as well as the Majorana mass matrix for the neutrinos are generated by higher dimension operators involving the flavon field. When the flavon field acquires a vacuum expectation value it breaks the flavor symmetry and thus generates the Yukawa couplings. The model is consistent with the nearly bimaximal solution to the solar and atmospheric neutrino deficits.

  3. Materia extraña

    CERN Document Server

    Gómez Cadenas, J J

    2008-01-01

    Enero, 1999. Unas extrañas burbujas se han colocado en el acelerador de particulas del CERN (Ginebra). Ante el riesgo de que esto desencadene una catástrofe a escala mundial, el centro ordena detener el experimento. Años después, Irene, una joven y promotedora científica, es contratada en la división de Física Teórica del CERN. Allí coincide con el mayor Espinosa, destinado a la sede suiza de la ONU para trabajar en un proyecto contra la proliferación de armas nucleares. La misión de Espinosa resulta ser mucho más arriesgada de lo que parecía. Irene ambiciosa y rebelde, toma una decisión de efectos imprevisibles.

  4. Exploring Extra Dimensions in Spectroscopy Experiments

    Institute of Scientific and Technical Information of China (English)

    LUO Feng; LIU Hong-Ya

    2006-01-01

    @@ We propose an idea in spectroscopy to search for extra spatial dimensions as well as to detect the possible deviation from Newton's inverse-square law at small scale, and we take high-Z hydrogenic systems and muonic atoms as illustrations. The relevant experiments might help to explore a more than two extra dimensions scenario in the brane world model proposed by Arkani-Hamed, Dimopoulos, Dvali (ADD) and to set constraints for fundamental parameters such as the size of extra dimensions.

  5. Pericoronal occurrence of cemento-ossifying fibroma: an unexemplified and unusual case report with review of literature.

    Science.gov (United States)

    K L, Kumaraswamy; R S, Arvind Babu; P, Sheshadri; Kumaran, Santhosh

    2014-03-01

    The Cemento-ossifying fibroma (COF) is an odontogenic neoplasm that is predominantly considered as a fibro osseous lesion of the jaw bone. The histogenetic origin of COF was thought to be derived from the periodontal cells, which have the ability to form fibrous, cementum and osseous tissue. Due to the periodontal cellular origin, the lesion often occurs in the radicular portion of the bicuspid and molar tooth region of the lower jaw. We present a case of Cemento-ossifying fibroma in a 43-year-old female in the pericoronal aspect of an impacted third molar mimicking an odontogenic lesion. The occurrence of COF in pericoronal region is an unusual site. This article also discusses about the various hamartomatous lesions occurring in the pericoronal region of the teeth.

  6. Three cases of osteoma and an osseous fibroma of the paranasal sinuses of horses in South Africa : clinical communication

    Directory of Open Access Journals (Sweden)

    I. Cilliers

    2008-05-01

    Full Text Available Four horses were presented to the Onderstepoort Veterinary Academic Hospital with histories of facial asymmetry, nasal discharge or obstruction of normal nasal passage airflow. Radiographic examination of the maxillary sinuses of 2 cases revealed well circumscribed, unilateral, mineralised masses; the other 2 cases showed less mineralisation. The masses were accessed for further investigation by surgically created frontonasal bone flaps or trephination of the maxillary sinuses. Diagnosis of osteoma was confirmed histopathologically in 3 of the cases and of ossifying fibroma in the 4th. Two horses were euthanased directly after surgical intervention due to poor prognosis. Osteomas are by nature expansile tumours and follow the complex communication of the sinuses, and therefore are not all amenable to surgical removal. Osseous fibromas are large, solitary, expansile lesions that are rare in all species but reported most frequently in horses. They have an apparent predilection for the rostral mandible of the horse.

  7. Congenital peripheral developing odontoma accompanied by congenital teratomatous fibroma in a 9-month-old boy: a case report.

    Science.gov (United States)

    Mikami, Toshinari; Yagi, Masaatsu; Mizuki, Harumi; Takeda, Yasunori

    2013-03-01

    Peripheral odontoma is rare, and only two cases of congenital peripheral odontoma have been reported. Congenital oral fibroma is also rare. We describe a unique case of congenital peripheral developing odontoma accompanied by congenital teratomatous fibroma in an infant. Both tumors were difficult to detect on radiography. Two small masses were seen in the median anterior portion of the palatal mucosa of a 9-month-old boy. The masses had been present since birth and were surgically removed at age 28 months, when one of the masses had grown to a diameter of 8 mm. Histopathologic examination showed a fibrous lesion and a tooth germ-like rounded lesion composed of dental papilla, enamel organ, dentin, and cementum. Although congenital odontoma is rare, it should be considered when selecting appropriate treatment, as early radiographic detection is difficult.

  8. Concomitant occurrence of cemento-ossifying fibroma and adenomatoid odontogenic tumor with bilateral impacted permanent canines in the mandible.

    Science.gov (United States)

    Prakash, A Ravi; Reddy, P Sreenivas; Bavle, Radhika M

    2012-01-01

    Adenomatoid odontogenic tumor (AOT) is an uncommon, benign and slow growing odontogenic tumor, which is usually located in an anterior region of the maxilla without pain. Cemento-ossifying fibroma (COF) is a relatively rare benign tumor of the jaw. Here we present 2 lesions presenting in unusual forms, follicular variant of AOT in the mandible and COF associated with impacted canine in the mandible, occurring concomitantly in the same patient. Both lesions presented classic histopathologic features.

  9. Juvenile cemento-ossifying fibroma of the maxilla:Report of one case and renew of the literature

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Juvenile cemento-ossifying fibroma (JCOF) is a rare lesion that exhibits a slow growing but may reach massive proportion and cause considerable cosmetic and functional problems.This lesion has the tendency for recurrence following incomplete excision.A case report of giant JCOF in a 46-year-old female with 23-year history is presented.Local excision and thorough curettage was performed and the normal skeletal structure was maximally preserved. 15month follow up demonstrated no sign of recurrence.

  10. Extra and intradural spinal Hemangioblastoma Hemangioblastoma espinal extra e intradural Hemangioblastoma espinhal extra e intradural

    Directory of Open Access Journals (Sweden)

    Marcelo Campos Moraes Amato

    2012-09-01

    Full Text Available Hemangioblastomas of the central nervous system (CNS are low-grade highly vascularized tumors that may be sporadic or associated with Von Hippel-Lindau disease. Extradural hemangioblastomas are uncommon and those located extra and intradurally are even rarer. This study uses an illustrative case and literature review to discuss the difficulties to consider the correct diagnosis and to select the best surgical approach. A 57 years-old white male patient presented with myelopathy and right C5 radiculopathy. The images showed a lobulated, hourglass shaped, highly enhanced extra/intradural lesion that occupied the spinal canal and widened the C4-C5 right intervertebral foramen. Total resection of the intradural lesion was achieved through a posterior approach, but the extradural part could only be partially removed. Complete improvement was observed after four months of follow-up and the residual tumor has been followed up clinically and radiologically. Even though the preoperative impression was of a spinal schwannoma, the histopathological examination revealed grade I hemangioblastoma as per WHO. Despite their rarity, current complementary exams allow considering the diagnosis of hemangioblastoma preoperatively. That is essential to a better surgical planning in view of the particular surgical features of this lesion.Hemangioblastomas del sistema nervioso central (SNC son tumores altamente vascularizados, de grado bajo, que pueden ser esporádicos o vinculados a la enfermedad de Von Hippel-Lindau. Hemangioblastomas extradurales no son comunes, y aquellos localizados extra e intraduralmente son aún más raros. Este estudio usa un caso ilustrativo y la revisión de la literatura para analizar las dificultades cuanto a considerar el diagnóstico correcto y para seleccionar el mejor abordaje quirúrgico. Un paciente, hombre blanco de 57 años de edad, presentaba mielopatía con radiculopatía C5 derecha. Las imágenes mostraban lesión extra

  11. Extra informatie op matrixborden : mogelijkheden en effecten.

    NARCIS (Netherlands)

    Craen, S. de & Niet, M. de

    2002-01-01

    In this report, the possibilities of displaying extra safety information on Dynamic Message Signs (DMSs) are explored. The technical possibilities for placing extra information on the signs are looked at, and the road safety effects are examined. The information to be displayed can be divided into t

  12. Extra dimensions at particle colliders

    Energy Technology Data Exchange (ETDEWEB)

    Dvergsnes, Erik Wolden

    2004-08-01

    This thesis consists of an introduction where we consider different aspects of theories involving extra dimensions, together with four research publications (Papers I-IV) attached at the end. The introductional chapters should serve as background material for better understanding the models on which the articles are based. In Chap. 4 we also present some plots not included in the papers. The topic of Papers I-III is graviton induced Bremsstrahlung. In Paper I we consider the contribution to this process from graviton exchange through gluon-gluon fusion at the LHC, compared to the QED background. Only final-state radiation is considered in Paper I, whereas in Paper II we extend this work to include also the quark-antiquark annihilation with graviton exchange, as well as initial-state radiation for both graviton and Standard Model exchange. Paper III is a study of graviton-induced Bremsstrahlung at e{sup +}e{sup -} colliders, including both initial- and final-state radiation. Paper IV is devoted to a study of the center-edge asymmetry at hadron colliders, an asymmetry which previously had been studied for e{sup +}e{sup -} colliders. The center-edge asymmetry can be used as a method of distinguishing between spin-1 and spin-2 exchange, something which will be of major importance if a signal is observed.

  13. Chondromyxoid Fibroma

    Science.gov (United States)

    ... is one of the rarest of bone tumors, accounting for less than 1% of all bone tumors. ... imaging scans. Doctors usually also request computed tomography (CT) scans or magnetic resonance imaging (MRI) scans to ...

  14. MR appearance of ovarian thecoma-fibromas%卵泡膜瘤-纤维瘤的MRI表现

    Institute of Scientific and Technical Information of China (English)

    周燕; 谢洁林; 钱慧君; 韩志刚; 张国福

    2014-01-01

    目的:分析卵巢卵泡膜瘤-纤维瘤的MRI表现,探讨MRI的诊断价值。方法:42例经手术病理证实的卵泡膜瘤-纤维瘤患者,回顾性分析其MRI表现。结果:本组病例中包括卵泡膜细胞瘤2例,纤维瘤21例,卵泡膜纤维瘤19例,肿瘤边界清楚,多呈实性。纤维瘤T2WI呈低信号15例,低信号为主混杂信号6例;卵泡膜细胞瘤T2WI均呈稍高信号为主混杂信号;卵泡膜纤维瘤T2WI呈低信号2例,等信号或稍高信号为主的混杂信号17例;所有肿瘤T1WI均呈等信号或低信号;增强扫描后38例为轻度延迟强化,3例无明显强化,1例显著持续强化。结论:卵巢卵泡膜瘤-纤维瘤的MRI表现具有一定特征性,对于临床定性、定位诊断均有较高参考价值。%ObjectiveTo analyze the MR appearance of ovarian thecoma -fibromas and investigate the diagnostic value of MRI.Methods: The MR images of 42 cases of ovarian thecoma -fibromas confirmed by histopathology were retrospectively analyzed.Re-sults:There were 2 cases thecoma , 21 cases fibroma and 19 cases fibrothecoma of 42 patients.Tumors were solid with well -defined margins.On T2WI, fibromas showed hypo -intensity in 15 cases and mixed intensity in 6 cases, thecoma showed slight hyper -inten-sity, fibrothecoma showed hypo -intensity in 2 cases and mixed intensity in 17 cases.All tumors showed iso -intensity or hypo -in-tensity on T1WI.Slight enhancement was shown in 38 cases, no enhancement in 3 cases, marked enhancement in 1 case after injection of contrast medium.Conclusion:MRI findings of ovarian thecoma -fibromas are characteristic and have a higher reference value in clinical qualitation and positioning diagnosis.

  15. Paraganglioma funcional extra-adrenal

    Directory of Open Access Journals (Sweden)

    Laura Arroyo-Martínez

    2006-03-01

    Full Text Available Los paragangliomas funcionales son tumores raros, se originan del tejido cromafín extraadrenal productor de catecolaminas, con frecuencia son malignos y tienen alta incidencia de enfermedad persistente o recurrente¹. Se les conoce como: glomus, quemodectomas, paragangliomas cromafines y glomerulocitomas. La localización es diversa y refleja la distribución paraganglionar en el cuerpo, desde la base del cráneo hasta el piso pélvico. Los paragangliomas se encuentran en donde hay ganglios del sistema autónomo, sin embargo, aproximadamente el 90% de estos tumores aparecen en las glándulas suprarrenales (y constituyen los feocromocitomas y el 10% restante tienen una ubicación extraadrenal, mas se ha dicho que su incidencia puede ser subestimada, variando del 18% al 22% en adultos, y en niños hasta un 30%. Los extra-adrenales se originan con mayor frecuencia en el abdomen (85%, otros en el tórax (12% y más raramente en la cabeza y el cuello (3% ². Los estudios de imágenes y la medición de la producción no fisiológica de catecolaminas pueden ayudar en el diagnóstico de esta entidad. La cirugía es el tratamiento de elección. Presentamos aquí el caso de una paciente de 32 años, primigesta con HTAIE que requirió cesárea, quien tuvo un postparto tórpido y pese a múltiples tratamientos antihipertensivos su patología fue de difícil manejo, con complicaciones oftálmicas. Tiempo después la paciente se estudia por hiperhidrosis, se solicitan exámenes de laboratorio e imágenes y se le documenta incidentalmente, una tumoración retroperitoneal izquierda, se le amplían los estudios, y se llega al diagnóstico correcto. La tumoración requirió resección quirúrgica. Tuvo un postoperatorio satisfactorio y la paciente egresó con control en la Consulta Externa.Functioning paragangliomas are rare tumors that produce catecholamines. They originate from extra-adrenal chromaffin cells. They are frequentIy malignant and are associated

  16. Malignant transformation of a rat fibroma by the treatment with an anti-fibrosing drug: CY-168F (Plastenan

    Directory of Open Access Journals (Sweden)

    Sonia G. Andrade

    1981-09-01

    Full Text Available Fifteen albino (Sprague Dawley rats with subcutaneous transplanted fibromas was used in the present study. The tumour was formed by typical fibroblasts in a dense collagen matrix and was provenient from a fibroma that appeared spontaneously in an albino rat of the same strain. Ultrastructurally collagen disclosed normal periodicity and the fibroblasts showed irregular notched nuclei with irregular distribution of chromatin, that suggests transitional aspects to fibrosarcoma. The 15 animals, from different passage groups, were divided into: 8 animals submitted to treatment with the drug acexamic acid (CY-168F - N acetyl-amino-6-hexanoic acid (plastenan and 7 untreated control animals. Three of the treated animals showed a malignant transformation to fibrosarcoma. transitional histological features from typical fibroma to highly indifferentiated fibrosarcoma could be detected in come animal subjected to repeated biopsies. Ultrastructural study disclosed nuclear alterations and hyperactive ergastoplasm and collagen containing inclusions into the cytoplasm of fibroblasts. In the group of 7 untreated naimals, no malignant transformation could be detected histologically. Two aspects deserve attention: the malignant potential of a typical fibroma and the apparent effect of an antifibrosing drug in inducing malignization of this tumour.Foram utilizados no presente estudo, quinze ratos albinos (Sprague Dawley portadores de fibronas transplantados no tecido subcutâneo da parede abdominal. O tumor era constituído por fibroblastos típicos, em uma densa matriz colagênica e eram provenientes de um fibroma que apareceu espontaneamente em um rato albino da mesma linhagem. Ultraestruturalmente o colágeno mostrava periodicidade normal e os fibroblastos mostravam núcleo irregularmente denteado, com cromatina irregularmente distribuída, sugerindo aspectos transicionais para um fibrossarcoma. Os quinze animais, de diferentes grupos de passagem do tumor, foram

  17. Hypocellular Plaque-Like CD34-Positive Dermal Fibroma (Medallion-Like Dermal Dendrocyte Hamartoma) Presenting as a Skin-Colored Dermal Nodule.

    Science.gov (United States)

    Mutgi, Krishna A J; Chitgopeker, Pooja; Ciliberto, Heather; Stone, Mary S

    2016-01-01

    Plaque-like CD34-positive dermal fibromas, also known as medallion-like dermal dendrocyte hamartomas (MDDHs), are a recently recognized group of congenital and acquired spindle cell neoplasms that may appear histologically similar to dermatofibrosarcoma protuberans. Recognizing the clinical heterogeneity of this neoplasm and the subtle pathologic differences are crucial to making the correct diagnosis and avoiding the aggressive surgical intervention required to treat a dermatofibrosarcoma protuberans. We present the case of a 9-year-old girl with an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Our case expands the clinical spectrum to include an acquired variant of a plaque-like CD34-positive dermal fibroma without clinical epidermal change. Examination of more cases is needed to determine whether all clinical variants are truly subtypes of the same neoplasm or represent distinct CD34-positive spindle cell proliferations.

  18. Congenital peripheral ameloblastic fibroma with intraosseous involvement in a 2-week-old infant: A case report with review of literature

    Directory of Open Access Journals (Sweden)

    Sabina Langer

    2015-01-01

    Full Text Available Ameloblastic fibroma is a rare, slow-growing benign mixed odontogenic tumor. It constitutes 2% of odontogenic tumors and is reported to occur at an age ranging from 6 months to 42 years. The youngest being a 7-week-old infant. We report a case of peripheral ameloblastic fibroma in a 2-week-old infant. The lesion presented since birth. It involved the maxilla with an extraosseous component involving the gingiva. A more or less conservative surgical approach of enucleation and curettage of the lesion was done under general anesthesia, trying to conserve the adjacent tooth buds. Only a few cases of congenital peripheral ameloblastic fibroma have been reported so far.

  19. Comparação da atividade de proliferação celular nos fibromas odontogênicos e ossificantes

    OpenAIRE

    Bruna Goncalves Garcia

    2008-01-01

    O fibroma odontogênico central (FOC) é uma condição rara classificada pela Organização Mundial da Saúde (OMS-2005) como uma neoplasia benigna de origem fibroblástica. O fibroma odontogênico periférico (FOP) é a contraparte periférica do FOC e, por se tratar de uma patologia rara, é objetivo de poucos estudos. O fibroma ossificante periférico (FOPE) não é considerado uma lesão neoplásica, e sim uma reação hiperplásica devido à presença de inflamação local, causada por fatores irritantes. O fib...

  20. Assessment of growth potential by MIB-1 immunohistochemistry in ameloblastic fibroma and related lesions of the jaws compared with ameloblastic fibrosarcoma.

    Science.gov (United States)

    Sano, K; Yoshida, S; Ninomiya, H; Ikeda, H; Ueno, K; Sekine, J; Iwamoto, H; Uehara, M; Inokuchi, T

    1998-02-01

    Specimens from two ameloblastic fibromas (including one recurrent case), two ameloblastic fibro-odontomas, and one ameloblastic fibrosarcoma were subjected to investigation by MIB-1 immunohistochemistry in order to elucidate the growth potential of these tumors. MIB-1 labeling indices in the epithelial component of these tumors ranged from 2.9 to 7.5%, whereas those in the mesenchymal component ranged from 1.5 to 13.5%. Of these, labeling indices in the mesenchymal component of the recurrent ameloblastic fibroma and ameloblastic fibrosarcoma were quite high. These findings suggest that evaluation of growth potential in ameloblastic fibroma and related lesions could be of help in understanding tumor aggressiveness and in selecting appropriate surgical procedures.

  1. Paraganglioma funcional extra-adrenal

    Directory of Open Access Journals (Sweden)

    Laura Arroyo-Martínez

    2006-03-01

    Full Text Available Los paragangliomas funcionales son tumores raros, se originan del tejido cromafín extraadrenal productor de catecolaminas, con frecuencia son malignos y tienen alta incidencia de enfermedad persistente o recurrente¹. Se les conoce como: glomus, quemodectomas, paragangliomas cromafines y glomerulocitomas. La localización es diversa y refleja la distribución paraganglionar en el cuerpo, desde la base del cráneo hasta el piso pélvico. Los paragangliomas se encuentran en donde hay ganglios del sistema autónomo, sin embargo, aproximadamente el 90% de estos tumores aparecen en las glándulas suprarrenales (y constituyen los feocromocitomas y el 10% restante tienen una ubicación extraadrenal, mas se ha dicho que su incidencia puede ser subestimada, variando del 18% al 22% en adultos, y en niños hasta un 30%. Los extra-adrenales se originan con mayor frecuencia en el abdomen (85%, otros en el tórax (12% y más raramente en la cabeza y el cuello (3% ². Los estudios de imágenes y la medición de la producción no fisiológica de catecolaminas pueden ayudar en el diagnóstico de esta entidad. La cirugía es el tratamiento de elección. Presentamos aquí el caso de una paciente de 32 años, primigesta con HTAIE que requirió cesárea, quien tuvo un postparto tórpido y pese a múltiples tratamientos antihipertensivos su patología fue de difícil manejo, con complicaciones oftálmicas. Tiempo después la paciente se estudia por hiperhidrosis, se solicitan exámenes de laboratorio e imágenes y se le documenta incidentalmente, una tumoración retroperitoneal izquierda, se le amplían los estudios, y se llega al diagnóstico correcto. La tumoración requirió resección quirúrgica. Tuvo un postoperatorio satisfactorio y la paciente egresó con control en la Consulta Externa.

  2. Extra dimensions in space and time

    CERN Document Server

    Bars, Itzhak

    2010-01-01

    Covers topics such as Einstein and the Fourth Dimension; Waves in a Fifth Dimension; and String Theory and Branes Experimental Tests of Extra Dimensions. This book offers a discussion on Two-Time Physics

  3. Chondromyxoid fibroma of the sacrum: A case report and literature review

    Directory of Open Access Journals (Sweden)

    Tanya Minasian

    2016-01-01

    Full Text Available Background: Chondromyxoid fibroma (CMF is an extremely rare, benign cartilaginous tumor that makes up <0.5% of all bone tumors, typically presenting in the second or third decade of life. CMF of the sacrum is exceedingly rare, with only seven documented cases reported in the neurosurgical literature. Case Description: We report a case of a 35-year-old female with a 3 month history of lower back pain after sustaining a fall on her sacrum/coccyx presenting with a progressive complaint of localized lower back pain, occasional urinary retention without incontinence, gluteal hypesthesia, and pressure below the gluteal crease. Imaging demonstrated a large, expansile enhancing soft-tissue lesion involving the sacrum, distal to the S2-3 disc space. The tumor was removed with partial sacrectomy for open en bloc resection with partial nerve sparing. The patient was found at 1.5-year follow-up with the improvement of symptoms, no recurrence, and no residual neurologic dysfunction. Conclusion: Sacral CMF is a rare clinical entity that may mirror more aggressive sacral pathology, including chordoma, in both clinical presentation and imaging characteristics. A review of the available literature regarding diagnosis, surgical management options, and prognosis for sacral CMF is provided.

  4. Juxtacortical chondromyxoid fibroma of bone: a unique variant: a case study of 20 patients.

    Science.gov (United States)

    Baker, Allyson C; Rezeanu, Luminita; O'Laughlin, Sabine; Unni, Krishnan; Klein, Michael J; Siegal, Gene P

    2007-11-01

    Chondromyxoid fibroma (CMF) is a rare neoplasm of the appendicular skeleton of young adults. We report 20 cases of a poorly recognized subtype which arises on the surface of long bones and erodes the cortical surface causing a periosteal reaction. This entity should be included in the differential diagnosis of bone surface lesions as it may be mistaken for a more aggressive neoplasm. A retrospective review at the Mayo Clinic identified 259 CMF cases, 13 of which were parosteal. Additionally, 2 cases were diagnosed at the University of Alabama at Birmingham and 5 cases were from one of our authors' files. We reviewed the clinical radiographic and pathologic findings of all 20 cases. Juxtacortical CMF occurred over a large age range (12 to 82 y) with a median age of 40.2 years. A slight male predilection (5:4) was seen. The most common presentation was bone pain. All 20 cases showed solitary, radiolucent surface lesions with sclerotic margins and extension into the overlying soft tissues. Most of the lesions were in the proximal tibial metaphysis. Histologically, the tumors had characteristic features of CMF. Several cases contained distinctive areas of calcification, which is not a feature of conventional CMF. Eleven of 12 cases were cured with simple excision. CMF should be included in the differential diagnosis of bone surface lesions. The clinical and radiologic findings must be known. The morphology of this lesion is similar to conventional CMF with the exception of focal exuberant calcification. Conservative therapy is the treatment of choice.

  5. Maxillo-Mandibular Cemento-ossifying Fibroma: A Rare Case Report.

    Science.gov (United States)

    Peravali, Ranjit Kumar; Bhat, H Hari Kishore; Reddy, Sreenatha

    2015-03-01

    Cemento-ossifying fibroma (COF) is a benign fibro osseous lesion of the jaws which has been described as a demarcated or rarely encapsulated neoplasm consisting of fibrous tissue and varying amounts of mineralized material resembling bone and/or cementum (Dinkar et al. in IJDA 2(4):45-47, 2010). Majority of lesions occur in the mandible and only few cases of COFs of the maxillary sinus and bilateral COFs of the mandible have been reported in literature (Dinkar et al. in IJDA 2(4):45-47, 2010; Tamiolakis et al. in Acta Stomatol Croat 39(3):319-321, 2005; Hamner et al. in Oral Surg Oral Med Oral Pathol 26(4):579-587, 1968; Gunaseelan et al. in Oral Med Oral Pathol Oral Radiol Endod 104:e21-e25, 2007). These lesions have a very low recurrence rate (Ertug et al. in Quintessence Int 35(10):808-810, 2004) and are generally treated by enucleation. In this paper we present a rare case of COF occurring in both the maxilla and mandible of the same patient. Only one such case (Takeda and Fujioka in Int J Oral Maxillofac Surg 16(3):368-371, 1987) has been reported in literature so far.

  6. FN1-EGF gene fusions are recurrent in calcifying aponeurotic fibroma.

    Science.gov (United States)

    Puls, Florian; Hofvander, Jakob; Magnusson, Linda; Nilsson, Jenny; Haywood, Elaine; Sumathi, Vaiyapuri P; Mangham, D Chas; Kindblom, Lars-Gunnar; Mertens, Fredrik

    2016-03-01

    Calcifying aponeurotic fibroma (CAF) is a soft tissue neoplasm with a predilection for the hands and feet in children and adolescents. Its molecular basis is unknown. We used chromosome banding analysis, fluorescence in situ hybridization (FISH), mRNA sequencing (RNA-seq), RT-PCR, and immunohistochemistry to characterize a series of CAFs. An insertion ins(2;4)(q35;q25q?) was identified in the index case. Fusion of the FN1 and EGF genes, mapping to the breakpoint regions on chromosomes 2 and 4, respectively, was detected by RNA-seq and confirmed by RT-PCR in the index case and two additional cases. FISH on five additional tumours identified FN1-EGF fusions in all cases. CAFs analysed by RT-PCR showed that FN1 exon 23, 27 or 42 was fused to EGF exon 17 or 19. High-level expression of the entire FN1 gene in CAF suggests that strong FN1 promoter activity drives inappropriate expression of the biologically active portion of EGF, which was detected immunohistochemically in 8/9 cases. The FN1-EGF fusion, which has not been observed in any other neoplasm, appears to be the main driver mutation in CAF. Although further functional studies are required to understand the exact pathogenesis of CAF, the composition of the chimera suggests an autocrine/paracrine mechanism of transformation. Copyright © 2015 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.

  7. Coverage Root after Removing Peripheral Ossifying Fibroma: 5-Year Follow-Up Case Report

    Science.gov (United States)

    Okajima, Luciana S.; Nunes, Marcelo P.; Montalli, Victor A. M.

    2016-01-01

    When lesions in soft tissue reach the gingival margin, they can produce aesthetic defects during its permanence and after its removal. Periodontal plastic surgery allows the correction of the gingival contour using different techniques. This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the affected area through two surgical phases: keratinized gingival tissue augmentation surgery with free gingival graft concurrent with removal of the lesion and, in a second stage, root coverage by performing coronally advanced flap technique with a follow-up of five years. The initial results achieved, which were root coverage of 100% after 6 months, promoted an adequate gingival contour and prevented the development of a mucogingival defect or a root exposure with its functional and aesthetic consequences. After five years, the results showed long term success of the techniques, where the margin remained stable with complete root coverage and tissues were stable and harmonic in color. PMID:27891263

  8. Coverage Root after Removing Peripheral Ossifying Fibroma: 5-Year Follow-Up Case Report

    Directory of Open Access Journals (Sweden)

    Paulo S. G. Henriques

    2016-01-01

    Full Text Available When lesions in soft tissue reach the gingival margin, they can produce aesthetic defects during its permanence and after its removal. Periodontal plastic surgery allows the correction of the gingival contour using different techniques. This paper is a case report of a peripheral ossifying fibroma removal in the interproximal area of teeth 21 and 22 in addition to root coverage of the affected area through two surgical phases: keratinized gingival tissue augmentation surgery with free gingival graft concurrent with removal of the lesion and, in a second stage, root coverage by performing coronally advanced flap technique with a follow-up of five years. The initial results achieved, which were root coverage of 100% after 6 months, promoted an adequate gingival contour and prevented the development of a mucogingival defect or a root exposure with its functional and aesthetic consequences. After five years, the results showed long term success of the techniques, where the margin remained stable with complete root coverage and tissues were stable and harmonic in color.

  9. Escisión de un fibroma de células gigantes con láser de diodo: Informe de un caso

    Directory of Open Access Journals (Sweden)

    C.M. Ardila Medina

    Full Text Available Este artículo informa un caso de un fibroma gigantocelular localizado en tejido gingival y mucosa oral. Microscópicamente, la lesión se caracterizó por proliferación de fibras colágenas y fibroblastos gigantes, que se disponían en forma densa e irregular. Además, la superficie de la lesión estaba revestida por epitelio con cambios de hiperqueratosis. Se realizó escisión del fibroma con láser de diodo.

  10. Pasta de azeite versus azeite virgem extra

    OpenAIRE

    Dias, Susana Marisa da Cunha

    2009-01-01

    Mestrado em Engenharia Alimentar - Instituto Superior de Agronomia Innovative products of high nutritional quality, with healthy benefits and extended conservation are an asset to the food sector. With beneficial health properties and high nutritional quality, extra virgin olive oil is an extraordinary fat, thanks to its unique chemical composition. The olive oil spread, subject of this study, is an innovative product, created from extra virgin olive oil, with a consistency ...

  11. Editorial: Focus on Extra Space Dimensions

    Science.gov (United States)

    Agashe, Kaustubh; Pomarol, Alex

    2010-07-01

    Experiments at the Large Hadron Collider (LHC) have just started. In addition to verifying the Standard Model (SM) of particle physics, these experiments will probe a new energy frontier and test extensions of the SM. The existence of extra dimensions is one of the most attractive possibilities for physics beyond the SM. This focus issue contains a collection of articles addressing both theoretical and phenomenological aspects of extra-dimensional models. Focus on Extra Space Dimensions Contents Minimal universal extra dimensions in CalcHEP/CompHEP AseshKrishna Datta, Kyoungchul Kong and Konstantin T Matchev Disordered extra dimensions Karim Benakli Codimension-2 brane-bulk matching: examples from six and ten dimensions Allan Bayntun, C P Burgess and Leo van Nierop Gauge threshold corrections in warped geometry Kiwoon Choi, Ian-Woo Kim and Chang Sub Shin Holographic methods and gauge-Higgs unification in flat extra dimensions Marco Serone Soft-wall stabilization Joan A Cabrer, Gero von Gersdorff and Mariano Quirós Warped five-dimensional models: phenomenological status and experimental prospects Hooman Davoudiasl, Shrihari Gopalakrishna, Eduardo Pontón and José Santiago

  12. Fibroma osificante periférico: Presentación de tres casos y revisión de la literatura Peripheral ossifying fibroma: Report of three cases and review of the literature

    OpenAIRE

    D. Pérez Álvarez; M.A. González Sánchez; L. Berini Aytés; C. Gay Escoda

    2011-01-01

    El fibroma osificante periférico (FOP) es una entidad benigna que se incluye en el grupo de las lesiones gingivales reactivas, denominadas con el término genérico de épulis, y se origina, según la teoría más aceptada, en las células del ligamento periodontal. Se manifiesta en forma de tumoración de consistencia firme, bien circunscrita, de color rosado o rojizo y está situada normalmente en la zona incisivo-canina del maxilar superior, siendo rara su aparición en crestas edéntulas. Aparece a ...

  13. Fibroma odontogénico central, tipo WHO: Reporte de un caso y revisión de la literatura Central odontogenic fibroma, WHO type: A case report and literature review

    Directory of Open Access Journals (Sweden)

    Carla Muñoz Torres

    2010-12-01

    Full Text Available El fibroma odontogénico central es una neoplasia benigna muy poco frecuente. Clásicamente se ha dividido en dos variantes histológicas: un tipo pobre en epitelio y otro tipo rico en epitelio con focos de material calcificado. En la mayoría de los casos muestra un crecimiento lento y progresivo con o sin sintomatología. Radiográficamente es habitual observar una imagen radiolúcida y unilocular que en raras ocasiones exhibe radiolucidez mixta. El tratamiento indicado en todos los casos es la enucleación del tumor. Se reporta el caso de una mujer de 36 años de edad, sin antecedentes mórbidos, con una lesión asintomática de radiolucidez mixta, expansiva de ambas corticales óseas, en la zona del cuerpo y ángulo mandibular izquierdo, asociada a un tercer molar incluido. Basándose en el estudio histopatológico inicial, se diagnosticó como fibroma odontogénico, y con el posterior tratamiento definitivo de la lesión, se determinó la subvariedad tipo OMS. La paciente no ha tenido recidiva en 16 meses de seguimiento.The central odontogenic fibroma is a rare benign neoplasm. Classically has been divided into two histological variants, a poor type epithelium and other rich epithelium with foci of calcified material. It shows in most cases, a slow and progressive growing with or without symptoms. Radiographically it is common to observe a radiolucent, unilocular, rarely exhibiting mixed radiolucency. The treatment in all cases is enucleation of the tumor. We report the case of a 36 year old woman, no morbid history, with an asymptomatic lesion of mixed radiolucency, cortical bone expansion in the area of the body and the left mandibular angle associated with a third molar. Based on the initial histopathology it was diagnosed as odontogenic fibroma and subsequent definitive treatment of the injury rate was determined sub manifold WHO. The patient had no recurrence at 16 months of follow-up.

  14. MR diagnosis of ovarian thecoma-fibromas%卵巢卵泡膜瘤-纤维瘤的MRI诊断

    Institute of Scientific and Technical Information of China (English)

    蒋兴德; 李伟大

    2013-01-01

    目的:探讨卵巢卵泡膜瘤-纤维瘤的MRI特点及其诊断价值.方法:回顾性分析经手术病理证实的12例卵泡膜瘤-纤维瘤的MRI表现.结果:12例卵泡膜瘤-纤维瘤中,卵泡膜细胞瘤4例,卵泡膜纤维瘤6例,纤维瘤2例.肿瘤最大径2.0~13.6cm,平均5.2cm.肿瘤呈圆形8例,卵圆形4例.全部肿瘤边界清楚,8例可见包膜显示.肿瘤信号均匀8例,小囊变3例,大囊变1例.所有肿瘤T1WI呈低或稍低信号(与子宫对比);卵泡膜细胞瘤T2WI呈高或稍高信号,卵泡膜纤维瘤T2WI呈低信号5例,稍高信号1例;纤维瘤T2WI呈低信号;所有肿瘤增强后均轻度强化.结论:卵泡膜瘤-纤维瘤的主要MRI表现为良性实性肿瘤的形态学特征及少血供的强化特点,肿瘤T2WI呈低信号结合少血供的强化特点对卵泡膜纤维瘤及纤维瘤的诊断具有重要定性诊断价值.%Objective:To evaluate the characteristics and diagnostic value of MRI in ovarian theco ma- fibroma. Methods: The MRI findings of 12 patients with surgery and pathology proved ovarian thecoma-fibroma were analyzed retrospectively. Results:Of the 12 patients, there were thecoma (4 cases) ,fibrothecoma (6 cases) and fibroma (2 cases). The largest dimension ranges from 2. 0~13. 6cm with the mean as 5. 2cm. Tumors were round (8 cases) or oval (4 cases) in shape with well-defined margin. 8 tumors showed homogeneous signal intensity, 3 cases with small cystic degeneration and one case with large cystic degeneration. Compared with the signal intensity of uterus,all tumors showed iso-intensity or slight hypo-intensity on T1-weighted images. On T2WI, thecoma showed hyper-/slight hyper- intensity, fibrotheeoma showed hypo-intensity in 5 cases and hyper-intensity in one case, fibroma showed hypointensity. After injection of contrast medium, all tumors showed slight enhancement. Conclusion: The main characteristics of ovarian theco ma-fibroma on MR imaging showed benign and solid tumor morphology and less

  15. 卵巢纤维瘤的CT和MRI表现%CT and MRI findings of ovarian fibroma

    Institute of Scientific and Technical Information of China (English)

    刘永强

    2015-01-01

    Objective To explore the imaging characteristics of ovarian fibroma on CT and MRI.Methods The CT and MRI findings of 12 patients with ovarian fibroma proved by surgery and pathology,including 12 cases of CT scan and 5 cases of MRI scan,were retrospectively analyzed.Results All of 12 patients with ovarian fibroma showed solitary masses with well defined margin and roughly round or mildly lobulated shape.On CT plain imaging,3 ovarian fibromas were homogeneous or roughly homogeneous solid masses,8 mixed masses with cystic and solid parts,and 2 mainly cystic masses.5 masses with MRI showed isointensity or mildly hypointensity on T1WI and significantly inhomogeneous intensity on T2WI with stripy and flaky hypointensity in solid parts.The solid parts of mass were enhanced slightly and gradually after intravenous administration of contrast material,and 4 masses showed complete envelopes on enhanced MRI.10 cases showed little of ascites concomitantly.Conclusion The CT and MRI findings of ovarian fibroma are characteristic to some extent.Masses with well defined margin and roughly round or mildly lobulated shape,slight and gradual enhancement,hypointensity of solid part on T2WI and complete envelope showed on MRI,suggest the possible diagnosis of ovarian fibroma.%目的 探讨卵巢纤维瘤的CT和MRI影像特征.方法 回顾性分析12例经手术病理证实的卵巢纤维瘤的CT(12例)、MRI(5例)表现.结果 12例卵巢纤维瘤均为单发,呈类圆形或浅分叶肿块,边界清楚;CT平扫显示实性密度均匀或稍不均匀3例;囊实性8例;囊性为主2例;5例肿瘤在MRI上显示为T1WI等及稍低信号,T2WI实性部分条状及片状低信号,且整体信号明显不均.增强后肿瘤实性部分均呈轻度渐进性强化,4例肿瘤MRI增强后显示完整的包膜.10例肿瘤伴有少量腹腔积液.结论 卵巢纤维瘤的CT、MRI表现有一定特征,边界清楚类圆形或浅分叶肿块,增强后实性部分均呈轻度渐进性强化,MRI显

  16. 卵巢纤维瘤的CT表现%CT Findings of Ovarian Fibroma in 9 Patients

    Institute of Scientific and Technical Information of China (English)

    刘梦雨; 薛华丹; 金征宇

    2012-01-01

    目的 探讨多层螺旋CT对卵巢纤维瘤的诊断价值.方法 回顾性分析2004年至2010年经病理证实的9例卵巢纤维瘤的CT征象,其中3例有增强检查.两名放射科大夫对图像进行诊断.结果 9例患者均表现为一侧附件区的肿块,边界清晰.按其CT表现分为3型:单纯型、变性型和合并腹水型.单纯型4例,表现为密度均匀的实性肿块,无强化,2例影像诊断为子宫肌瘤,2例诊断为卵巢来源的良性肿瘤;变性型3例,肿块边界清晰,内有圆形或不规则形低密度影,无强化,影像诊断为恶性1例、盆腔占位2例;合并腹水型2例,肿块密度均匀,无强化,1例伴有腹盆腔积液,1例伴有右侧胸腔积液、腹盆腔积液,影像诊断均为恶性肿瘤,卵巢来源可能性大.结论卵巢纤维瘤的CT表现多样化,多表现为一侧附件区边界清楚的实性肿块,无明显强化,若伴有胸腔积液和腹腔积液,则可诊断为Meigs综合征.%Objective To study the value of multislice spiral computed tomography ( CT) in the diagnosis of ovarian fibroma. Method The CT findings of 9 cases with pathologically confirmed ovarian fibroma were retrospectively analyzed by two radiologists. Results All of the 9 cases showed unilateral adnexal mass with demarcated boundary. There were three different types of ovarian fibroma according to the CT appearances : simple type ( n = 4 ) , degeneration type ( n = 3 ) and the ovarian fibroma with ascites ( n = 2 ) . The simple type showed homogeneous-density solid tumor with no enhancement; two of them diagnosed as uterine leiomyomas and the other two as benign tumor originated from the ovary. The degeneration type showed irregular or round hypodensity inside the tumor with no enhancement; one of them was diagnosed as malignant tumor and the other two as intrapelvic mass. The ovarian fibroma with ascites showed homogeneous density with no enhancement ; one with ascites and pelvic effusion and the other one with pleural

  17. Intra-articular fibroma of tendon sheath in a knee joint associated with iliotibial band friction syndrome

    Energy Technology Data Exchange (ETDEWEB)

    Ha, Dong Ho; Choi, Sun Seob; Kim, Soo Jin; Lih, Wang [Dong-A University Medical Center, Busan (Korea, Republic of)

    2015-02-15

    Iliotibial band (ITB) friction syndrome is a common overuse injury typically seen in the active athlete population. A nodular lesion on the inner side of the ITB as an etiology or an accompanying lesion from friction syndrome has been rarely reported. A 45-year-old male presented with recurrent pain and a movable nodule at the lateral joint area, diagnosed as ITB friction syndrome. The nodule was confirmed as a rare intra-articular fibroma of the tendon sheath (FTS) on the basis of histopathologic findings. We describe the MRI findings, arthroscopic and pathologic features, in this case of intra-articular FTS presenting with ITB friction syndrome.

  18. CLINICOPATHOLOGIC STUDY OF AMELOBLASTIC FIBROMA%造釉细胞纤维瘤的临床病理分析

    Institute of Scientific and Technical Information of China (English)

    聂旭光; 郭玲玲; 李大鲁

    2000-01-01

    @@ 成釉细胞纤维瘤(ameloblastic fibroma)是一种少见的牙源性肿瘤,其间质和上皮成分均为肿瘤性质,因而属一种真性牙源性混合瘤,临床报道较少,在临床和病理学方面均有显著特点,本文对11例病例进行了分析讨论.

  19. Giant fibroma in the left ventricle of an infant: imaging findings in magnetic resonance imaging, echocardiography and angiography

    Energy Technology Data Exchange (ETDEWEB)

    Gutberlet, Matthias; Felix, Roland [Department of Radiology and Nuclear Medicine, Charite, Campus Virchow-Klinikum, Augustenburger Platz 1, 13353 Berlin (Germany); Abdul-Khaliq, Hashim; Stiller, Brigitte; Schubert, Ulf; Lange, Peter E. [Department of Pediatric Cardiology, Deutsches Herzzentrum, Berlin (Germany); Stoltenburg-Didinger, Gisela [Department of Neuropathology, Free University Berlin, Berlin (Germany); Hetzer, Roland [Department of Cardio-, Thoracic and Vascular Surgery, Deutsches Herzzentrum Berlin (Germany)

    2002-07-01

    The diagnosis of a rare case of giant intraventricular fibroma in an infant by MRI in comparison with other imaging modalities, such as echocardiography and angiography, is discussed. For preoperative planning only MRI showed the myocardial infiltration. The myocardial blood supply of the tumor could be evaluated qualitatively by contrast-enhanced MRI, but the direct visualization of the distally located branches could only be assessed by coronary angiography. Magnetic resonance coronary angiography using the navigator technique failed to depict the distal part of the coronaries. The obstruction of the left ventricle outflow tract could be assessed and quantified by all imaging modalities. (orig.)

  20. Intra-articular fibroma of tendon sheath in a knee joint associated with iliotibial band friction syndrome.

    Science.gov (United States)

    Ha, Dong-Ho; Choi, Sunseob; Kim, Soo-Jin; Lih, Wang

    2015-01-01

    Iliotibial band (ITB) friction syndrome is a common overuse injury typically seen in the active athlete population. A nodular lesion on the inner side of the ITB as an etiology or an accompanying lesion from friction syndrome has been rarely reported. A 45-year-old male presented with recurrent pain and a movable nodule at the lateral joint area, diagnosed as ITB friction syndrome. The nodule was confirmed as a rare intra-articular fibroma of the tendon sheath (FTS) on the basis of histopathologic findings. We describe the MRI findings, arthroscopic and pathologic features, in this case of intra-articular FTS presenting with ITB friction syndrome.

  1. Fibroma odontogênico periférico: revisão da literatura e relato de caso

    OpenAIRE

    Capelozza, Ana Lúcia Avares; Moreira,Carla Ruffeil; FERRAZ, Bruna F. Rahal; Sant’ana, Luís Fernando de Mello; Lara,Vanessa Soares

    2016-01-01

    O fibroma odontogênico periférico (FOP) é uma neoplasia benigna com origem a partir do ectomesênquima odontogênico. A lesão possui crescimento lento e acomete a gengiva, com maior incidência na região da papila interdentária. Apresenta-se com uma massa gengival freqüentemente séssil, de consistência firme, recoberta por mucosa aparentemente normal. O presente trabalho objetiva relatar um caso de FOP na região anterior de maxila, relacionando os achados da literatura pertinente, especialmente,...

  2. Anaplastic ameloblastic fibrosarcoma arising from recurrent ameloblastic fibroma: restricted molecular abnormalities of certain genes to the malignant transformation.

    Science.gov (United States)

    Williams, Michelle D; Hanna, Ehab Y; El-Naggar, Adel K

    2007-07-01

    A rare case of anaplastic ameloblastic fibrosarcoma (AS) arising in an ameloblastic fibroma (AF) of the maxilla of a 48-year-old patient 10 years after the primary excision is presented. The recurrent tumor retained focal areas of AF but manifested heterogeneous malignant features ranging from low-grade spindle to highly pleomorphic sarcomas. Biomarker analysis showed alterations of the p53 and c-KIT genes restricted to the sarcomatous component. The biological implications of these findings in the future management of these tumors are discussed.

  3. Ameloblastic Fibrosarcoma of the mandible evolving from a prior Ameloblastic Fibroma after two years: an unusual finding.

    Science.gov (United States)

    Bertoni, Franco; Del Corso, Giacomo; Bacchini, Patrizia; Marchetti, Claudio; Tarsitano, Achille

    2016-10-01

    Transformation of an ameloblastic fibroma to an ameloblastic fibrosarcoma has been reported rarely in the literature. The present case report describes such evolution in a patient under long-term follow-up. The patient was first treated in 2008, and he developed the malignant counterpart of the disease 2 years later. The patient is currently under careful long-term follow-up and is free of disease. This article describes the clinical and radiographic features, histological characteristics, immunohistochemical findings, and surgical treatment of the tumor. © The Author(s) 2016.

  4. Fibroma desmoplásico del alvéolo maxilar asociado a esclerosis tuberosa: reporte de caso

    OpenAIRE

    Mejía Cortés, Maddy; Departamento de Patología, Hospital Universitario San Ignacio, Bogotá, Colombia. Docente del Departamento de Patología, Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia.; De León Rodríguez, Oscar; Odontólogo cirujano maxilofacial, Hospital Universitario San Ignacio. Profesor de la Facultad de Medicina, Pontificia Universidad Javeriana, Bogotá, Colombia.; Peña, Claudia; Pontificia Universidad Javeriana, Bogotá, Colombia. Facultad de Odontología, Universidad Nacional de Colombia.; Paez, Jorge; Pontificia Universidad Javeriana, Bogotá, Colombia.; Solarte, Paula; Pontificia Universidad Javeriana; Bermúdez Rey, Maria Carolina; Pontificia Universidad Javeriana, Bogotá, Colombia

    2016-01-01

     La esclerosis tuberosa es un trastorno autosómico dominante que se manifiesta con la formación de hamartomas en múltiples órganos y sistemas, como el sistema nervioso central, la piel, los riñones, los pulmones y el corazón. Los pacientes se ven afectados por cuadros de convulsiones, así como por hallazgos cutáneos. En la cavidad oral, las lesiones se presentan en el esmalte dental y constituyen la presentación más frecuente, pero rara vez se encuentran lesiones en los maxilares. El fibroma ...

  5. Seguimiento de un fibroma ameloblástico con transformación maligna a fibrosarcoma ameloblástico.

    OpenAIRE

    Galindo Obando, Ursula; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Delgado Azañero, Wilson; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima.; Calderón Ubaqui, Víctor; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Beltrán Silva, Jorge; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Huamaní Parra, Jaime; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima.; Paniura Rodriguez, Dithel; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,; Anchayhua Espinoza, Miguel; Facultad de Estomatología, Universidad Peruana Cayetano Heredia. Lima,

    2014-01-01

    La transformación maligna de un tumor odontogénico es poco común y puede desarrollarse a partir de un tumor odontogénico benigno. Se presenta el caso de una paciente de sexo femenino de 19 añosde edad, con el seguimiento secuencial de las radiografías y tomografía computarizada de una lesión inicialmente diagnosticada como Ameloblastoma, que posterior al tratamiento quirúrgico se establececomo Fibroma ameloblastico y al cabo de seis años sufre una transformación maligna determinado con un dia...

  6. Extra-oral halitosis: an overview.

    Science.gov (United States)

    Tangerman, A; Winkel, E G

    2010-03-01

    Halitosis can be subdivided into intra-oral and extra-oral halitosis, depending on the place where it originates. Most reports now agree that the most frequent sources of halitosis exist within the oral cavity and include bacterial reservoirs such as the dorsum of the tongue, saliva and periodontal pockets, where anaerobic bacteria degrade sulfur-containing amino acids to produce the foul smelling volatile sulfur compounds (VSCs), especially hydrogen sulfide (H(2)S) and methyl mercaptan (CH(3)SH). Tongue coating is considered to be the most important source of VSCs. Oral malodor can now be treated effectively. Special attention in this overview is given to extra-oral halitosis. Extra-oral halitosis can be subdivided into non-blood-borne halitosis, such as halitosis from the upper respiratory tract including the nose and from the lower respiratory tract, and blood-borne halitosis. The majority of patients with extra-oral halitosis have blood-borne halitosis. Blood-borne halitosis is also frequently caused by odorous VSCs, in particular dimethyl sulfide (CH3SCH3). Extra-oral halitosis, covering about 5-10% of all cases of halitosis, might be a manifestation of a serious disease for which treatment is much more complicated than for intra-oral halitosis. It is therefore of utmost importance to differentiate between intra-oral and extra-oral halitosis. Differences between intra-oral and extra-oral halitosis are discussed extensively. The importance of applying odor characterization of various odorants in halitosis research is also highlighted in this article. The use of the odor index, odor threshold values and simulation of bad breath samples is explained.

  7. Dark Energy as Evidence for Extra Dimensions

    CERN Document Server

    Milton, K A

    2003-01-01

    It is argued that fluctuations of quantum fields in four-dimensional space do not give rise to dark energy, but are rather a negligible contribution to dark matter. By (relativistic) dark matter we mean that the relation between pressure and energy density is $p=\\frac13 u$, while dark energy is characterized by $p=-u$. A possible source of dark energy are the fluctuations in quantum fields, including quantum gravity, inhabiting extra compactified dimensions. These fluctuations have been computed for some simple geometries, such as $S^2$, $S^4$, and $S^6$. If the extra dimensions are too small, they would give rise to a dark energy larger than that observed, whereas if they are too large they would be in conflict with experimental tests of Newton's law. This notion suggests that the size of the extra dimensions is of order 100 $\\mu$m. If the limit on the size of extra dimensions becomes lower than this bound, extra dimensions probably do not exist, and another source for cosmological dark energy will have to b...

  8. Meig’s Syndrome:A Triad of Pleural Effusion, Abdominal Ascites, and Benign Ovarian Fibroma

    Institute of Scientific and Technical Information of China (English)

    Yaseen Ali; Amila M. Parekh; Rahul K. Rao; Taseen Ali; Linda S. Schneider; Jordan Garvey; Mirza R. Baig

    2015-01-01

    Background:Meig’s syndrome is a rare syndrome characterized by a triad of recurrent pleural effusions, ascites, and the finding of a benign ovarian fibroma on diagnostic imaging and histopathological evaluation. Patients can present with any of the constellation of symptoms attributing to the disease state. With pleural effusions they can present with shortness of breath, chest pressure, dyspnea on exertion; symptoms that can be confused with the exacerbation of congestive heart failure. Ascites can present with abdominal tenseness, pain, bloating, cramping, constipation, and elevated liver enzymes. The ifnding of a benign ovarian ifbroma is found only during diagnostic imaging and histopathological evaluation. Case report:The patients was an 85-year-old female with a recent history of coronary artery bypass graft surgery for her severe coronary artery disease presented with the chief complaint of generalized malaise, abdominal pain, constipation of few days. She was initially scheduled to have her second therapeutic thoracentesis for her recurrent pleural effusion as an outpatient procedure but complained of the former symptoms and was admitted for observation and treatment of her abdominal symptoms. Her recurrent pleural effusions were initially attributed to the complications of her coronary artery bypass graft surgery for her severe coronary artery disease. During the admission and evaluation she was diagnosed with Meig’s syndrome. She underwent a left oophorectomy with total abdominal hysterectomy that led to the resolution of all her symptoms. Conclusion:Meig’s syndrome is a rare syndrome characterized by the triad of recurrent pleural effusions, ascites, and the ifnding of a benign ovarian ifbroma. The diagnosis and knowledge of this syndrome holds the key to its treatment. The treatment generally involves the resection of the ovarian ifbroma. After the resection of the ovarian ifbroma patients recover from the inconvenient pleural effusions and

  9. Ameloblastic fibroma: a review of published studies with special reference to its nature and biological behavior.

    Science.gov (United States)

    Chen, Yan; Wang, Jing-Ming; Li, Tie-Jun

    2007-11-01

    To further elucidate confusions with respect to the nature and biological behavior of ameloblastic fibroma (AF), available English-language literature since its first description in 1891 was reviewed. A total number of 123 cases with well-documented follow-up data were retrieved to evaluate various clinical, pathological and behavioral aspects of this tumor. AF tends to occur in the first two decades (89/123; 72.4%), but patients older than 22 years are not uncommon (30 cases). An overall recurrence rate of 33.3% (41 cases) is identified in reported cases who were treated by conservative (91.5%) and radical (8.5%) methods. Malignant transformation is evident in 14 recurrent tumors with an overall transformation rate of 11.4%. These data support the view that majority of AFs are true neoplasms. However, a small number of AFs occurring in childhood may represent the primitive stage of a developing odontoma, as three of the reported recurrent AFs do show further maturation with formation of dental hard tissues. A significantly longer recurrence-free survival was noted in patients treated by radical procedures in comparison to those treated by conservative methods and the age of patients at the first presentation was significantly related to malignant transformation of AF. As we are unable, at present, to differentiate a hamartomatous lesion from a neoplasm among this group of lesions merely on histologic grounds, age of the patients should be an important consideration when choosing therapeutic methods. Radical surgery should not be employed for the treatment of AFs in young people.

  10. Ameloblastic fibroma and related lesions: a clinicopathologic study with reference to their nature and interrelationship.

    Science.gov (United States)

    Chen, Yan; Li, Tie-Jun; Gao, Yan; Yu, Shi-Feng

    2005-11-01

    Ameloblastic fibroma (AF) and related lesions constitute a group of lesions, which range in biologic behavior from true neoplasms to hamartomas. The aim of this study was to elucidate the nature and interrelationship of this group of lesions. Clinical and pathological studies were undertaken retrospectively on 13 cases of AF and seven cases of ameloblastic fibro-odontoma (AFO). Thirty-three complex odontomas and 33 compound odontomas were also included for comparative purpose. Relevant follow-up data were recorded and the literature was reviewed. The majority of patients with AF (nine cases, 69.2%) were over the age of 22 years with frequent involvement (76.9%) of the posterior mandible. Tumors recurred in four of 11 patients with follow-up information and two recurrent tumors showed malignant transformation. There was no case in this series that could be designated as the so-called ameloblastic fibrodentinoma, apart from one recurrent AF in which further maturation to form only tubular dentin materials was identified. AFO tended to occur at a younger age group with an average of 9.6 years. Recurrence was noted in two of five patients with follow-up data and both recurrent lesions showed limited growth potential and further maturation into a complex odontoma. Significant differences were noted in the age and site distribution between the complex and the compound odontomas. Whilst the majority, if not all, of AFs are true neoplasms with a potential to recur and/or of malignant transformation, some, especially those occurred during childhood, could represent the primitive stage of a developing odontoma. Our data also suggests that some AFOs are hamartomatous in nature, representing a stage preceding the complex odontoma.

  11. 骨韧带样纤维瘤临床病理观察%Desmoplastic fibroma of bone:a clinicopathologic observation

    Institute of Scientific and Technical Information of China (English)

    马云秀

    2012-01-01

    Objective: To investigate the clinico - pathological characteristics and differential diagnosis of desmo-plastic fibroma of bone. Methods: A case with desmoplastic fibroma of costal bone was studied by microscopic observation and immunohistochemical staining. Results: Desmoplastic fibroma of bone contains myofibroblasts. Immuno-histochemical staining showed that the tumor cells were positive for vimentin, partially for actin and SMA, but negative for S - 100, CD34, CD57, NF. Conclusion: Desmoplastic fibroma of bone is a rare tumor. The diagnosis should be differented from other mesenchymal tumors of bone.%目的:探讨骨韧带样纤维瘤的临床病理特征.方法:通过光镜及免疫组化方法对1例肋骨韧带样纤维瘤进行观察,同时复习相关文献.结果:骨韧带样纤维瘤瘤细胞由成纤维细胞组成.免疫组化:肿瘤细胞Vimentin弥漫阳性,actin、SMA部分阳性、S-100、CD34、CD57、NF均阴性.结论:骨的韧带样纤维瘤是一种罕见肿瘤,需与骨其它间叶性肿瘤鉴别.

  12. Compact Extra Dimensions in Quantum Mechanics

    CERN Document Server

    Deutschmann, Nicolas

    2016-01-01

    Extra-dimensions are a common topic in popular descriptions of theoretical physics with which undergraduate student most often have no contact in physics courses. This paper shows how students could be introduced to this topic by presenting an approach to two basic consequences of the presence of compact extra-dimensions based on undergraduate-level physics. The insensibility of low-energy physics to compact extra dimensions is illustrated in the context of non-relativistic quantum mechanics and the prediction of Kaluza-Klein excitations of particles is discussed in the framework of relativistic wave-equations. An exercise that could be used as a follow-up to the "particle in a box" is proposed.

  13. Extra-dimensional models on the lattice

    CERN Document Server

    Knechtli, Francesco

    2016-01-01

    In this review we summarize the ongoing effort to study extra-dimensional gauge theories with lattice simulations. In these models the Higgs field is identified with extra-dimensional components of the gauge field. The Higgs potential is generated by quantum corrections and is protected from divergencies by the higher dimensional gauge symmetry. Dimensional reduction to four dimensions can occur through compactification or localization. Gauge-Higgs unification models are often studied using perturbation theory. Numerical lattice simulations are used to go beyond these perturbative expectations and to include non-perturbative effects. We describe the known perturbative predictions and their fate in the strongly-coupled regime for various extra-dimensional models.

  14. Extra-pulmonary manifestations of sarcoidosis

    Energy Technology Data Exchange (ETDEWEB)

    Vardhanabhuti, V. [Radiology Department, Derriford Hospital, Plymouth (United Kingdom); Venkatanarasimha, N. [St Michael' s Hospital, 30 Bond Street, Toronto, Ontario M5B 1W8 (Canada); Bhatnagar, G.; Maviki, M.; Iyengar, S.; Adams, W.M. [Radiology Department, Derriford Hospital, Plymouth (United Kingdom); Suresh, P., E-mail: sureshpriya2000@yahoo.com [Radiology Department, Derriford Hospital, Plymouth (United Kingdom)

    2012-03-15

    Although, the diagnosis and evaluation of sarcoidosis has traditionally remained confined to the chest, its multi-system nature has been widely recognized. Radiological features of pulmonary sarcoidosis are well known but extra-pulmonary manifestations can produce a plethora of non-specific imaging findings that can affect subcutaneous tissue, and the neurological, cardiac, gastrointestinal, urological, liver, spleen, and skeletal systems. In the literature, there are various case reports and specific system reviews but there are few reviews that encompass all the extra-pulmonary manifestations. In this paper, we comprehensively review the imaging features of extra-pulmonary sarcoidosis with characteristic features as well as atypical presentations. In addition, we discuss the emerging role of nuclear medicine in sarcoidosis.

  15. Ossifying fibroma: report on a clinical case, with the imaging and histopathological diagnosis made and treatment administered

    Directory of Open Access Journals (Sweden)

    Daniel Trivelato da Silveira

    2016-02-01

    Full Text Available ABSTRACT The aim was to report on a case of ossifying fibroma, consisting of a benign fibro-osseous lesion characterized by slow growth and proliferation of fibrous cellular tissue, bone, cement or a combination. A 29-year-old male patient was attended at a hospital, after he had suffered a car accident. During the clinical examination, increased volume in the region of the right side of the mandible was observed, and a fracture in the middle third of the face was suspected. The tomographic examination showed an image suggestive of fracturing of the left-side zygomatic complex, without displacement, and with a well-delimited radiopaque image of the mandible. The patient was sent to a hospital where panoramic radiography, posteroanterior radiography of the face and teleradiography were performed in order to better document the case. An incisional biopsy was performed. Histopathological examination showed the presence of a benign bone lesion suggestive of ossifying fibroma. Surgery was performed in order to completely remove the lesion, with fixation using a reconstruction plate. A new anatomopathological examination confirmed the diagnosis.

  16. Central ossifying fibroma, periapical cemento-osseous dysplasia and complex odon-toma occurring in the same jaw.

    Science.gov (United States)

    Hosseini, Farzaneh Agha; Moslemi, Elham

    2011-05-16

    Central ossifying fibroma is a rare, benign fibro-osseous lesion that arises from the periodontal ligament. Periapical cemento-osseous dysplasia is another variant of fibro-osseous lesion which occurs in the anterior region of the mandible of females. Odontoma is a benign odontogenic tumor that contains enamel, dentine cement and pulp tissue. A 46-year-old woman was referred to the Department of Oral Medicine, School of Dentistry, Tehran University of Medical Sciences, with two non-painful swellings on both sides of the mandible, which had been slowly growing over a period of one year. Our differential diagnosis was florid cemento-osseous dysplasia, focal cemento-osseous dysplasia for the right side, complex odontoma for the left side and periapical cement-osseous dysplasia for the anterior side. The historical feature revealed ossifying fibroma, complex odontoma and periapical cemento-osseous dysplasia. The occurrence of these three lesions in the same jaw has been rarely reported in the literature. The relationship between the occurrence of these three lesions is not obvious it could be coincidental. It seems that more case reports are needed to establish the relationship between them.

  17. Mediation of supersymmetry breaking in extra dimensions

    CERN Document Server

    Scrucca, C A

    2004-01-01

    I review the mechanisms of supersymmetry breaking mediation that occur in sequestered models, where the visible and the hidden sectors are separated by an extra dimension and communicate only via gravitational interactions. By locality, soft breaking terms are forbidden at the classical level and reliably computable within an effective field theory approach at the quantum level. I present a self-contained discussion of these radiative gravitational effects and the resulting pattern of soft masses, and give an overview of realistic model building based on this set-up. I consider both flat and warped extra dimensions, as well as the possibility that there be localized kinetic terms for the gravitational fields.

  18. Electromagnetism from extra space multi connectivity

    Energy Technology Data Exchange (ETDEWEB)

    Gauthier, C. [Moncton Univ., Moncton (France). Dept. de Mathematiques et de Statistique

    2001-09-01

    In a unified field theory of the Kaluza-Klein type, it is used a multi connected extra space to interpret geometrically the quantum properties of physics. This paper presents a pure geometric interpretation of electromagnetism. The electric change of a body is identified with its cross-section for interaction of twisted waves due to the extra space multi connectivity. A by-product of this interpretation is an expression for the permittivity of free space as an integral of the flux of these waves over their frequencies.

  19. Signatures of extra dimensional sterile neutrinos

    Directory of Open Access Journals (Sweden)

    Werner Rodejohann

    2014-10-01

    Full Text Available We study a large extra dimension model with active and sterile Dirac neutrinos. The sterile neutrino masses stem from compactification of an extra dimension with radius R and are chosen to have masses around eV or keV, in order to explain short-baseline anomalies or act as warm dark matter candidates. We study the effect of the sterile neutrino Kaluza–Klein tower in short-baseline oscillation experiments and in the beta spectrum as measurable by KATRIN-like experiments.

  20. Signatures of extra dimensional sterile neutrinos

    Energy Technology Data Exchange (ETDEWEB)

    Rodejohann, Werner, E-mail: werner.rodejohann@mpi-hd.mpg.de; Zhang, He, E-mail: he.zhang@mpi-hd.mpg.de

    2014-10-07

    We study a large extra dimension model with active and sterile Dirac neutrinos. The sterile neutrino masses stem from compactification of an extra dimension with radius R and are chosen to have masses around eV or keV, in order to explain short-baseline anomalies or act as warm dark matter candidates. We study the effect of the sterile neutrino Kaluza–Klein tower in short-baseline oscillation experiments and in the beta spectrum as measurable by KATRIN-like experiments.

  1. The Higgs Mechanism from an extra dimension

    CERN Document Server

    A., Yu

    2016-01-01

    The standard $SU(2) \\times U(1)$ fields are considered in 4D plus one extra compact dimension. As a result two basic effects are obtained. First, four Goldstone-like scalars are produced, three of them are used to create longitudinal modes of the $W,Z$ fields, while the fourth becomes the Higgs-like scalar. Second, $W$ and $Z$ get their masses from the extra compact dimension with the standard pattern of symmetry violation. The resulting theory has the same fields as in the standard model, but without the Higgs vacuum average. The properties of the new Higgs scalar and its interaction with fermions are briefly discussed.

  2. Phenomenology of symmetry breaking from extra dimensions

    CERN Document Server

    Alfaro, J; Gavela-Legazpi, Maria Belen; Rigolin, S; Salvatori, M

    2007-01-01

    Motivated by the electroweak hierarchy problem, we study the symmetry breaking pattern induced by a background magnetic flux living on extra dimensions, with the four-dimensional scalar fields being gauge boson components in full space. For SU(N) and two compact, toroidal, extra dimensions, we determine analytically the possible field configurations of stable vacua and their symmetries. From the four-dimensional point of view, the system responds dynamically to the magnetic background by an infinite chain of vacuum expectation values so as to reach a stable vacuum. The equivalence between flux compactification and constant boundary conditions - either Scherk-Schwarz or twisted - is established.

  3. Correlation between expressions of hypoxia -inducible factor (HIF-1α, blood vessels density, cell proliferation, and apoptosis intensity in canine fibromas and fibrosarcomas

    Directory of Open Access Journals (Sweden)

    Madej Janusz A.

    2014-03-01

    Full Text Available The study aimed to demonstrate the expression of hypoxia-inducible factor (HIF-1α in soft tissue mesenchymal tumours (fibroma and fibrosarcoma in dogs. An attempt was made to correlate the obtained results with density of blood vessels (expression of von Willebrand Factor, vWF, expression of Ki-67 proliferation antigen, and with intensity of apoptosis in studied tumours. The study was performed on paraffin sections of 15 fibromas and 40 fibrosarcomas sampled from 55 female dogs aged 6 to 16 years. Immunohistochemical staining against HIF-1α, vWF, and Ki-67 was performed. Apoptosis was detected with the use of TUNEL reaction. A significantly higher HIF-1α expression was noted in fibrosarcomas in comparison to fibromas (P < 0.0001. HIF-1α expression in fibromas manifested strong positive correlation with tumour vascularity (r = 0.67, P = 0.007. Moreover, HIF-1α expression in fibrosarcomas manifested a moderate positive correlation with tumour malignancy grade (r = 0.44, P = 0.004, tumour vascularity (r = 0.52, P < 0.001, Ki-67 antigen expression (r = 0.42; P = 0.007, and TUNELpositive cells (r = 0.37, P = 0.017. Expression of HIF-1α was detected in 86.7% of fibroma type tumours and in 100% of fibrosarcomas. In all studied tumours expression of HIF-1α manifested positive correlation with the density of blood vessels, and in fibrosarcomas it correlated also with malignancy grade, intensity of Ki-67 expression, and with intensity of apoptosis in tumour cells.

  4. Nasopharyngeal angio-fibroma with intracranial extension: Situating the chemotherapy-radiotherapy association; L'angiofibrome nasopharyngien avec extension intracranienne: place de l'association chimiotherapie-radiotherapie

    Energy Technology Data Exchange (ETDEWEB)

    Belcadhia, M.; Mania, R.; Harzallah, M.; Bouzouita, K. [CHU Farhat-Hached de Sousse, Service d' ORL et de Chirurgie Cervicofaciale, Sousse (Tunisia); Bouaouina, N. [CHU Farhat-Hached de Sousse, Service de Radiotherapie, Sousse (Tunisia)

    2008-09-15

    Nasopharyngeal angio-fibroma is a locally aggressive, although histologically benign, vascular neoplasm. This neoplasm accounts for 0.05% of head and neck tumours and affects almost exclusively male adolescents. Surgery is considered as the primary treatment of nasopharyngeal angio-fibroma. Other treatment modalities such as radiotherapy and chemotherapy are still recommended for intracranial extension involving the cavernous sinus or the internal carotid artery. We report a rare case of nasopharyngeal angio-fibroma, further complicated with a Kennedy syndrome in a 34 year-old women. The treatment consisted in a chemotherapy (adriamycin, decarbazine) followed by radiotherapy. We discuss the relevance and outcome of the association chemotherapy-radiotherapy in the treatment of nasopharyngeal angio-fibroma with a consistent intracranial extension (stage III B of Arch Otolaryngol Head Neck Surg 122 (2003) 122-129). (authors)

  5. Seguimiento radiológico en paciente con fibroma condromixoide del seno frontal: Diagnóstico diferencial, alternativas terapéuticas y revisión de la literatura Radiological follow-up of a patient with chondromyxoid fibroma of the frontal sinus: Differential diagnosis, therapeutic alternatives and a revision of the literature

    Directory of Open Access Journals (Sweden)

    I. Zubillaga Rodriguez

    2006-12-01

    Full Text Available Introducción. El fibroma condromixoide es un tumor benigno de crecimiento lento y poco frecuente. Su incidencia en la región craneofacial es rara, especialmente en el seno frontal. Objetivos. Presentamos el seguimiento a largo plazo de un paciente intervenido en relación a un fibroma condromixoide del seno frontal. Se discuten los distintos diagnósticos diferenciales y las alternativas terapéuticas. Discusión. Desde el punto de vista de anatomía patológica es necesario hacer el diagnóstico diferencial con condrosarcoma, mixosarcoma, mixoma y cordoma. Desde el punto de vista radiológico, el diagnóstico de fibroma condromixoide ha de ser considerado en toda lesión ósea aislada con expansión u osteolisis, márgenes lobulados y septos intralesionales. El tratamiento del fibroma condromixoide incluye principalmente curetaje o resección en bloque, mientras que la radioterapia aislada no se considera de primera elección. Conclusiones. La naturaleza benigna del fibroma condromixoide implica la importancia de evitar tratamientos radicales. El abordaje subcraneal se presenta como una alternativa válida para el tratamiento de lesiones localizadas en el seno frontal. Es fundamental un seguimiento clínico-radiológico adecuado para identificar precozmente posibles recidivas.Introduction. Chondromyxoid fibroma is a slow growing and rare benign bone tumor. Its location in the craniofacial skeleton is not common, especially in the frontal sinus. Objectives. We present a long-term follow-up of a patient with a frontal chondromyxoid fibroma who was operated four years ago. We discuss the various differential diagnoses and possible treatments. Discussion. The differential diagnosis includes chondrosarcoma, myxosarcoma, myxoma and chordoma. From the radiological point of view, chondromyxoid fibroma must be always considered as a diagnostic possibility when a solitary bone lesion appears with expansion or cortical osteolysis, lobulated margins and

  6. Extra-1 acupressure for children undergoing anesthesia.

    Science.gov (United States)

    Wang, Shu-Ming; Escalera, Sandra; Lin, Eric C; Maranets, Inna; Kain, Zeev N

    2008-09-01

    Acupuncture and related techniques have been used as adjuncts for perioperative anesthesia management. We examined whether acupressure in the Extra-1 (Yin-Tang) point would result in decreased preprocedural anxiety and reduced intraprocedural propofol requirements in a group of children undergoing endoscopic procedures. Fifty-two children were randomized to receive acupressure bead intervention either at the Extra-1 acupuncture point or at a sham point. A Bispectral Index (BIS) monitor was applied to all children before the onset of the intervention. Anxiety was assessed at baseline and before entrance to the operating room. Anesthetic techniques were standardized and maintained with IV propofol infusion titrated to keep BIS values of 40-60. We found that after the intervention, children in the Extra-1 group experienced reduced anxiety whereas children in the sham group experienced increased anxiety (-9% [-3 to -15] vs 2% [-6 to 7.4], P = 0.012). In contrast, no significant changes in BIS values were observed in the preprocedural waiting period between groups (P = ns). We also found that total intraprocedural propofol requirements did not differ between the two study groups (214 +/- 76 microg x kg(-1) x min(-1) vs 229 +/- 95 microg x kg(-1) x min(-1), P = 0.52). We conclude that acupressure bead intervention at Extra-1 acupoint reduces preprocedural anxiety in children undergoing endoscopic procedures. This intervention, however, has no impact on BIS values or intraprocedural propofol requirements.

  7. Gauge coupling unification with extra Higgs doublets

    Energy Technology Data Exchange (ETDEWEB)

    Harada, Junpei [Research Center for Higher Education, Health Sciences University of Hokkaido (Japan)

    2016-06-15

    Gauge coupling unification is studied within the framework where there are extra Higgs doublets and E{sub 6} exotic fields. Supersymmetric models and nonsupersymmetric models are investigated, and a catalog of models with gauge coupling unification is presented. (copyright 2016 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  8. Precision constraints on extra fermion generations.

    Science.gov (United States)

    Erler, Jens; Langacker, Paul

    2010-07-16

    There has been recent renewed interest in the possibility of additional fermion generations. At the same time there have been significant changes in the relevant electroweak precision constraints, in particular, in the interpretation of several of the low energy experiments. We summarize the various motivations for extra families and analyze them in view of the latest electroweak precision data.

  9. Probing Extra Dimensions with Neutrino Oscillations

    Energy Technology Data Exchange (ETDEWEB)

    Machado, P.A.N. [Instituto de Fisica, Universidade de Sao Paulo, C. P. 66.318, 05315-970 Sao Paulo (Brazil); Nunokawa, H. [Departamento de Fisica, Pontificia Universidade Catolica do Rio de Janeiro, C. P. 38071, 22452-970 Rio de Janeiro (Brazil); Zukanovich Funchal, R., E-mail: zukanov@fma.if.usp.br [Instituto de Fisica, Universidade de Sao Paulo, C. P. 66.318, 05315-970 Sao Paulo (Brazil)

    2011-08-15

    We consider a model where sterile neutrinos can propagate in a large compactified extra dimension (a) giving rise to Kaluza-Klein (KK) modes and the Standard Model left-handed neutrinos are confined to a 4-dimensional spacetime brane. The KK modes mix with the standard neutrinos modifying their oscillation pattern. We examine current experiments in this framework obtaining stringent limits on a.

  10. Extra-oral halitosis : an overview

    NARCIS (Netherlands)

    Tangerman, A.; Winkel, E. G.

    2010-01-01

    Halitosis can be subdivided into intra-oral and extra-oral halitosis, depending on the place where it originates. Most reports now agree that the most frequent sources of halitosis exist within the oral cavity and include bacterial reservoirs such as the dorsum of the tongue, saliva and periodontal

  11. Cystic lesions accompanying extra-axial tumours

    NARCIS (Netherlands)

    Lohle, PNM; Wurzer, HAL; Seelen, PJ; Kingma, LM; Go, KG

    1999-01-01

    We examined the mechanism of cyst formation in extra-axial tumours in the central nervous system (CNS). Cyst fluid, cerebrospinal fluid (CSF) and blood plasma were analysed in eight patients with nine peritumoral cysts: four with meningiomas, two with intracranial and two spinal intradural schwannom

  12. Extra dimensions and violations of Lorentz symmetry

    CERN Document Server

    Overduin, James M

    2016-01-01

    We use experimental limits on Lorentz violation to obtain new constraints on Kaluza-Klein-type theories in which the extra dimensions may be large but do not necessarily have units of length. The associated variation in fundamental quantities such as rest mass must occur slowly, on cosmological scales.

  13. The Night Of Hennessy Paradis Extra Cognac

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    <正>The world-known Hennessy Paradis Extra Cognaclaunched its"dazzling night"on the evening of May 22 tolet guests enjoy to their hearts’content the fine wine andthe charming glamour of the diamond evening dress. A liquid,dating back to the 18th century,was called

  14. A Case Reported of Perineal Region Soft Fibroma in Adolescence%青春期会阴部软纤维瘤1例报道

    Institute of Scientific and Technical Information of China (English)

    范召应

    2012-01-01

    Objective : A case of the clinical and pathologic character of soft Fibroma of perineal re- gion. Methods: To investigate a 16-year-old girl presente with a soft Fibroma of perineal region and con- jugate the reported of previous documents, it may identify the clinical character and the therapy method of soft Fibroma. Results: A 16-year-old girl presented with a soft Fibroma of perineal region for four years. Special body examine : A excrescence with pedicle located in the right bottom of labium majus pudendi, it is about 8.0 x 6.2 x 4.4cm, the pedicle is small, it is about 0.5cm in diameter. Pathologic diagnosis: soft fibroma. Conclusions: The soft Fibroma of perineal region in puberty is rare, it is a kind of benign tumor and need operate as soon as possible. 2figs. ,8refs.%目的:报道1例青春期会阴部软纤维瘤的临床特点及病理特点.方法:通过1例16岁女性软纤维瘤患者,结合文献报道,明确软纤维瘤的特点及治疗方法.结果:患者,女,16岁,发现会阴部肿物4年.专科体查:右侧大阴唇外下方可及一带蒂赘生物,约8.0×6.2×4.4cm,蒂部细,直径约0.5cm.病理诊断:软纤维瘤.结论:青春期会阴部软纤维瘤少见,它是一种良性肿瘤,应尽快手术治疗.图2,参8.

  15. Construction Process Control of Large Extra Caissons

    Institute of Scientific and Technical Information of China (English)

    HU Shaowei; WANG Hongxia; FAN Jiansheng

    2005-01-01

    The complexity of geotechnical engineering and variability in construction circumstances of large extra caissons make the problem of maintaining appropriate sink attitude quite difficult, especially in keeping sink uniformity and achieving the expected final sink depth. A new construction control method is presented using (H∞) theory, considering uncertainties in the mechanics model and external noise in the construction site parameters. The design method of an (H∞) controller has consequently been obtained for large extra caissons. Control results using only constructor experiences are compared with simulation results using the (H∞) controller for a practical engineering situation, which indicates that the (H∞) controller is successful in maintaining sink uniformity, avoiding sink as well as in achieving the expected final sink depth.

  16. Brane modeling in warped extra-dimension

    CERN Document Server

    Ahmed, Aqeel

    2012-01-01

    Five-dimensional scenarios with infinitesimally thin branes replaced by appropriate configurations of a scalar field were considered. A possibility of periodic extra dimension was discussed in the presence on non-minimal scalar-gravity coupling and a generalized Gibbons-Kallosh-Linde sum rule was found. In order to avoid constraints imposed by periodicity, a non-compact spacial extra dimension was introduced. A five dimensional model with warped geometry and two thin branes mimicked by a scalar profile was constructed and discussed. In the thin brane limit the model corresponds to a set-up with two positive-tension branes. The presence of two branes allows to address the issue of the hierarchy problem which could be solved by the standard warping of the four dimensional metric. Stability of the background solution was discussed and verified in the presence of the most general perturbations of the metric and the scalar field.

  17. Indirect Collider Signals for Extra Dimensions

    CERN Document Server

    Hewett, J L

    1999-01-01

    A recent suggestion that quantum gravity may become strong near the weak scale has several testable consequences. In addition to probing for the new large (submillimeter) extra dimensions associated with these theories via gravitational experiments, one could search for the Kaluza Klein towers of massive gravitons which are predicted in these models and which can interact with the fields of the Standard Model. Here we examine the indirect effects of these massive gravitons being exchanged in fermion pair production in \\epem\\ annihilation and Drell-Yan production at hadron colliders. In the latter case, we examine a novel feature of this theory, which is the contribution of gluon gluon initiated processes to lepton pair production. We find that these processes provide strong bounds, up to several TeV, on the string scale which are essentially independent of the number of extra dimensions. In addition, we analyze the angular distributions for fermion pair production with spin-2 graviton exchanges and demonstrat...

  18. Extra-dimensional confinement of quantum particles

    CERN Document Server

    Hedin, Eric R

    2016-01-01

    A basic theoretical framework is developed in which elementary particles have a component of their wave function extending into higher spatial dimensions. This model postulates an extension of the Schrodinger equation to include a 4th and 5th spatial component. A higher-dimensional simple harmonic oscillator confining potential localizes particles into 3-d space, characterizing the brane tension which confines Standard Model particles to the sub-manifold. Quantum effects allow a non-zero probability for a particle's evanescent existence in the higher dimensions, and suggest an experimental test for the validity of this model via particles being temporarily excited into the first excited state of the extra-dimensional potential well, in which their probability of existing in 3-d space transiently drops to zero. Several consistency checks of the outcomes of this extra-dimensional model are included in this paper. Among the outcomes of this model are: a match with the quantum phenomenon of zitterbewegung; the pr...

  19. Celulitis por cuerpo extraño

    Directory of Open Access Journals (Sweden)

    Miguel B. Carrasco Guzmán

    2016-01-01

    Full Text Available Las infecciones de la piel y el tejido celular subcutáneo surgen como un grupo importante de afecciones con una alta morbilidad en edades pediátricas, generalmente relacionada con traumatismo y cuerpos extraños. Se presenta el caso de una escolar femenina de 6 años de edad, con síntomas y signos clínicos que sugieren celulitis en el muslo derecho,  por su evolución tórpida se le realizó el estudio ultrasonográfico que confirmó el diagnóstico etiológico de una celulitis secundaria a un traumatismo, provocada por la introducción de un gran cuerpo extraño, que pasó inadvertido para a familia de la menor.

  20. Neutrino anomalies and large extra dimensions

    CERN Document Server

    Dighe, A S; Dighe, Amol S.; Joshipura, Anjan S.

    2001-01-01

    Theories with large extra dimensions can generate small neutrino masses when the standard model neutrinos are coupled to singlet fermions propagating in higher dimensions. The couplings can also generate mass splittings and mixings among the flavour neutrinos in the brane. We systematically study the minimal scenario involving only one singlet bulk fermion coupling weakly to the flavour neutrinos. We explore the neutrino mass structures in the brane that can potentially account for the atmospheric, solar and LSND anomalies simultaneously in a natural way. We demonstrate that in the absence of a priori mixings among the SM neutrinos, it is not possible to reconcile all these anomalies. The presence of some structure in the mass matrix of the SM neutrinos can solve this problem. This is exemplified by the Zee model, which when embedded in extra dimensions in a minimal way can account for all the neutrino anomalies.

  1. Origin of extra chromosome in Patau syndrome.

    Science.gov (United States)

    Ishikiriyama, S; Niikawa, N

    1984-01-01

    Five live-born infants with Patau syndrome were studied for the nondisjunctional origin of the extra chromosome. Transmission modes of chromosomes 13 from parents to a child were determined using both QFQ- and RFA-heteromorphisms as markers, and the origin was ascertained in all of the patients. The extra chromosome had originated in nondisjunction at the maternal first meiotic division in two patients, at the maternal second meiosis in other two, and at the paternal first meiosis in the remaining one. Summarizing the results of the present study, together with those of the previous studies on a liveborn and abortuses with trisomy 13, nondisjunction at the maternal and the paternal meiosis occurred in this trisomy in the ratio of 14:3. This ratio is not statistically different from that inferred from the previous studies for Down syndrome. These findings suggest that there may be a fundamental mechanism common to the occurrence of nondisjunction in the acrocentric trisomies.

  2. Precision Constraints on Extra Fermion Generations

    CERN Document Server

    Erler, Jens

    2010-01-01

    In the recent past there has been renewed interest in the possibility of additional fermion generations. At the same time there have been significant changes in the relevant electroweak (EW) precision constraints, in particular in the interpretation of several of the low energy experiments. We summarize the various motivations for the increased activity regarding extra families and analyze them in view of the latest EW precision data.

  3. Extra gauge symmetries in BHT gravity

    CERN Document Server

    Blagojević, M

    2011-01-01

    We study the canonical structure of the Bergshoeff-Hohm-Townsend massive gravity, linearized around a maximally symmetric background. At the critical point in the space of parameters, defined by $\\Lambda_0/m^2=-1$, we discover an extra gauge symmetry, which reflects the existence of the partially massless mode. The number of the Lagrangian degrees of freedom is found to be 1. We show that the canonical structure of the theory at the critical point is unstable under linearization.

  4. Extra gauge symmetries in BHT gravity

    Science.gov (United States)

    Blagojević, M.; Cvetković, B.

    2011-03-01

    We study the canonical structure of the Bergshoeff-Hohm-Townsend massive gravity, linearized around a maximally symmetric background. At the critical point in the space of parameters, defined by Λ 0/ m 2 = -1, we discover an extra gauge symmetry, which reflects the existence of the partially massless mode. The number of the Lagrangian degrees of freedom is found to be 1. We show that the canonical structure of the theory at the critical point is unstable under linearization.

  5. Quantum simulation of an extra dimension.

    Science.gov (United States)

    Boada, O; Celi, A; Latorre, J I; Lewenstein, M

    2012-03-30

    We present a general strategy to simulate a D+1-dimensional quantum system using a D-dimensional one. We analyze in detail a feasible implementation of our scheme using optical lattice technology. The simplest nontrivial realization of a fourth dimension corresponds to the creation of a bi-volume geometry. We also propose single- and many-particle experimental signatures to detect the effects of the extra dimension.

  6. Dimensional reduction without continuous extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Chamseddine, Ali H. [American University of Beirut, Physics Department, Beirut, Lebanon and I.H.E.S. F-91440 Bures-sur-Yvette (France); Froehlich, J.; Schubnel, B. [ETHZ, Mathematics and Physics Departments, Zuerich (Switzerland); Wyler, D. [Institute of Theoretical Physics, University of Zuerich (Switzerland)

    2013-01-15

    We describe a novel approach to dimensional reduction in classical field theory. Inspired by ideas from noncommutative geometry, we introduce extended algebras of differential forms over space-time, generalized exterior derivatives, and generalized connections associated with the 'geometry' of space-times with discrete extra dimensions. We apply our formalism to theories of gauge- and gravitational fields and find natural geometrical origins for an axion- and a dilaton field, as well as a Higgs field.

  7. Collider Implications Of Extra Dimensions At Lhc

    CERN Document Server

    Reema

    2005-01-01

    Scope and method of study. The intent of this research is to consider multiple TeV-1-size extra compact dimensions in an asymmetric string compactification scenario in which the SM gauge bosons can propagate into the TeV-1-size extra dimensions while the SM fermions are confined to the usual SM D3-brane. The contributions that the KK excitations of the gluons, g*'s, make to the multijet cross sections in proton- proton collisions at the LHC energy are calculated. Fortran was used to do the calculations. Findings and conclusions. At very high pT, the dijet signal will either be enhanced significantly due to virtual g* exchanges or place a lower bound on the compactification scale of about 8 TeV. It is found that the dijet signal is very sensitive to three parameters—the compactification scale, the string scale, and the number of extra dimensions. Thus, although the dijet signal is much more sensitive to KK effects, the dijet signal alone does not provide sufficient information to deduce the number of...

  8. MR findings of extra abdominal fibromatosis

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hee Jin; Lee, Sung Moon; Rhee, Chang Soo; Sohn, Chul Ho; Lee, Hee Jung; Kim, Jung Sik; Kim, Hong [Dongsan Medical Center, Keimyung Univ. College of Medicine, Taegu (Korea, Republic of); Seo, Kyung Jin [Suh Joo MRI center, Seoul (Korea, Republic of); Jo, Kil Ho [Youngnam Univ. College of Medicine, Kyongsan (Korea, Republic of)

    1999-12-01

    To evaluate the MR findings of extra-abdominal fibromatosis and the role of MRI in primary diagnosis Fifteen cases in of histologically proven extra-abdominal fibromatosis in 13 patients were retrospectively reviewed. T1-weighted and T2-weighted images were obtained in axial, coronal and sagittal planes. Gd-enhancement was performed in 14 cases, and dynamic enhancement studies in two. All lesions were evaluated for mass shape and margin definition. Among the 15 cases, tumors of the buttock accounted for five, and tumor of the thigh for two. in eight cases tumors were intermuscular and in six cases were intramuscular. In ten cases (67%) the mass extended along the long axis of the body and in 14 of 15 cases (93%) focal infiltration of adjacent structures was visible. The signal intensity of the lesion was in all cases inhomogeneous on both T1 and T2 weighted images. As seen on Gd-DTPA enhanced scans, the masses were inhomogeneously enhanced. In all cases MRI revealed star-shaped linear strands or a band-like low signal area in the mass. These features were not enhanced and were arranged along the long axis of the mass. MR findings of extra-abdominal fibromatosis were relatively characteristic and helpful for primary diagnosis of the condition.

  9. Case presentation of florid cemento-osseous dysplasia with concomitant cemento-ossifying fibroma discovered during implant explantation.

    Science.gov (United States)

    Gerlach, Robert C; Dixon, Douglas R; Goksel, Tamer; Castle, James T; Henry, Walter A

    2013-03-01

    A 39-year-old African American woman presented for treatment of a symptomatic mandibular right first molar with a large, periapical radiolucency. After initial attempts at endodontic therapy, this tooth was ultimately extracted owing to unabated symptoms. The extraction site underwent ridge preservation grafting, implant placement, and restoration. After 26 months of implant function, the patient returned with clinical symptoms of pain, buccal swelling, and the sensation of a "loose" implant. This case report details a diagnosis of 2 distinct disease entities associated with the implant site, a cemento-ossifying fibroma and florid cemento-osseous dysplasia of the mandible. This diagnosis was determined from clinical, surgical, radiographic, and histopathologic evidence after biopsy and removal of the previously osseointegrated implant following postinsertion failure by fibrous encapsulation. Before implant therapy, it is essential to conduct a thorough radiographic evaluation of any dental arch with suspected bony lesions to prevent implant failure. Published by Mosby, Inc.

  10. Artificial Dermis Graft on the Mandible Lacking Periosteum After Excision of an Ossifying Fibroma: A Case Report

    Directory of Open Access Journals (Sweden)

    Chun-Ming Chen

    2007-07-01

    Full Text Available Collagen-based grafts have often been used as artificial tissue substitutes for the repair of tissue and organ defects. It is common surgical knowledge that autogenous or artificial skin grafts take well on the intact periosteum of bone. However, many experienced surgeons indicate that auto-genous or artificial skin grafts subsist poorly on the bone surface without periosteum. Therefore, primary closure is usually recommended in the wound healing of exposed bone. Vestibuloplasty might be needed to create enough depth of vestibule in the future. In this case report, we describe a peripheral ossifying fibroma surgically excised leaving a bony defect, which was covered by a piece of artificial dermis. Satisfactory result of the repaired surgical defect showed no need of vestibuloplasty after 6 years of follow-up.

  11. Epithelial Dysplasia in Ameloblastic Fibrosarcoma Arising from Recurrent Ameloblastic Fibroma in a 26-Year-Old Iranian Man.

    Science.gov (United States)

    Mohsenifar, Zhaleh; Behrad, Samira; Abbas, Fatemeh Mashhadi

    2015-08-18

    BACKGROUND Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumor with a mesenchymal component, showing sarcomatous features and epithelial nests resembling ameloblastic fibroma (AF). CASE REPORT We report a case of AFS showing epithelial dysplasia arising in a recurrent AF in the left mandible after 3 years in a 26-year-old man, which is regarded as an uncommon histopathologic finding in AFS. We also emphasize the comprehensive clinical, radiographic, and histopathologic evaluation, and immunohistochemical staining of this patient. CONCLUSIONS We conclude that it is important to consider malignancy alternations in the epithelial component of AFS, along with that of the mesenchymal component, to provide a proper diagnosis and treatment of recurrent AF.

  12. 骨硬纤维瘤的影像学表现分析%Imaging Features of Bone Desmoplastic Fibroma

    Institute of Scientific and Technical Information of China (English)

    王立兴; 陈明祥; 高文峰

    2012-01-01

    Objective To investigate the imaging features of bone desmoplastic fibroma. Methods The clinical and imaging data of 7 cases with pathologically confirmed bone desmoplastic fibroma were analyzed retrospectively. Results All the bone desmoplastic fibroma of 7 cases were located in the limbs bone, and all were single lesions, including 3 cases of femur, 2 cases of tibia, 1 case of fibula, and 1 case of radial bone. Five cases located in the metaphysis, and 2 cases in the backbone. The results of X-ray and CT were as follows: 4 cases were of central cystic expansion change, 3 cases were of eccentric cystic expansion change, the wall of tumors was seen to have different levels of hardening, with bone ridge of different thickness, of which 3 cases were of "Roots " like tumor bone trabecula, without any matrix calcification and periosteal reaction. The performance of MRI was as follow: 2 patients showed low-signal lesions in T1WI, the lesion signal equaled to or slightly was lower with the surrounding muscle in T2WI , of which small patchy or cord-like high signal could be shown, and the heterogeneous enhancement could be seen for the enhanced scan. Conclusion The imaging of bone desmoplastic fibroma has certain characteristics, so correct preoperative clinical diagnosis will be helpful for the clinicaldiagnosis and the correct assessment of prognosis.%目的:探讨骨硬纤维瘤的影像表现特征.方法:回顾性分析经病理证实的7例骨硬纤维瘤的临床及影像学资料.结果:7例骨硬纤维瘤均位于四肢管状骨,均为单发病灶,其中股骨3例、胫骨2例、腓骨1例、桡骨1例.位于干骺端5例、骨干2例.X线及CT表现为:中心性囊状膨胀性改变4例,偏心性囊状膨胀性改变3例,瘤壁见不同程度硬化,内见粗细不等的骨嵴,其中3例可见“根须”状肿瘤性骨小梁,均无钙化基质及骨膜反应.MRI表现:2例病灶T1WI呈等低信号,T2WI上病灶信号与周围肌肉相等或略低,其中可见

  13. Report of Two Cases of Combined Odontogenic Tumors: Ameloblastoma with Odontogenic Keratocyst and Ameloblastic Fibroma with Calcifying Odontogenic Cyst.

    Science.gov (United States)

    Neuman, Ashley Nicole; Montague, Lindsay; Cohen, Donald; Islam, Nadim; Bhattacharyya, Indraneel

    2015-09-01

    Combined odontogenic neoplasms have rarely been documented. Such tumors have also been described by other researchers as "hybrid" lesions. The histologic features are often identical to other individually well-established odontogenic neoplasms such as ameloblastoma, adenomatoid odontogenic tumor, ameloblastic fibroma (AF), and ameloblastic fibro-odontoma. Their clinical presentation is variable, ranging from cysts to neoplasms showing varying degrees of aggressive behavior. Most combined tumors contain features of one of the odontogenic tumors in combination with either a calcifying odontogenic cyst (COC) or a calcifying epithelial odontogenic tumor. We present two new cases of combined odontogenic tumors: an ameloblastoma with an odontogenic keratocyst and an AF with COC. Predicting clinical outcome is challenging when a combination tumor is encountered due to the paucity of such lesions. One must understand salient features of these entities and differentiate them from the more common conventional neoplasms to expand classification and provide prognostic criteria.

  14. Locally infiltrative ameloblastic fibroma in a rhesus macaque (Macaca mulatta) with characterizations of its proliferating activity and biological behavior.

    Science.gov (United States)

    Liu, David X; Doyle, Lara A; Bouljihad, Mostafa T; Didier, Peter J; Gilbert, Margaret H; Wang, Xiaolei; Pahar, Bapi; Bohm, Rudolf P; Veazey, Ronald S; Lackner, Andrew A

    2012-05-01

    An 8-year-old male rhesus macaque (Macaca mulatta) presented with unilateral enlargement of the left mandible. Radiographs revealed a marked expansion of the left mandible with a multilocular radiolucent mass with abundant osteolysis. The mass was grossly firm, fleshy, and gelatinous on the cut surface. Histologically, the mass was locally infiltrative and composed of neoplastic epithelial and mesenchymal components that stained positive for cytokeratin and vimentin, respectively. Occasional densely spherical condensations of fibroblasts resembling the cap stage of odontogenesis were present in the mesenchyma. Immunohistochemical staining with Ki-67, S-100, and CD34 indicated that both epithelial and mesenchymal components of the neoplasm had low proliferation. Alcian blue, periodic acid-Schiff, and trichrome stains showed an immature stromal component with no collagen formation. Based on the clinical, histologic, and immunophenotypic features, the tumor was identified as a locally infiltrative ameloblastic fibroma.

  15. Extensive ameloblastic fibroma in an adolescent patient: a case report with a follow-up of 4 years.

    Science.gov (United States)

    Pitak-Arnnop, Poramate; Chaine, André; Dhanuthai, Kittipong; Bertrand, Jacques-Charles; Bertolus, Chloé

    2009-07-01

    Ameloblastic fibroma (AF) is a rare odontogenic tumour of the jaw which usually occurs in the first 2 decades of life. The common clinical manifestation is a slow-growing swelling. We report a case of a 16-year-old male patient presenting with extensive AF of the mandible. He underwent a conservative enucleation. The tumour recurred 2 years after the initial surgery, requiring the second enucleation. The patient has continued to be followed closely and has been disease-free for 4 years. Recent evidence suggests that the recurrent rate of AF is relatively high, and malignant transformation of AF may occur after recurrences or multiple surgeries. A conservative treatment approach with close surveillance is recommended. Anatomical limitations should be taken into account, especially when enucleation of AF in the posterior portion of the jaw is performed. Current surgical pathologic issues of the tumour are also discussed.

  16. Desmoplastic fibroma of the distal radius: an interesting case and a review of the literature and therapeutic implications.

    Science.gov (United States)

    Beebe, Kathleen S; Ippolito, Joseph A

    2016-01-13

    Desmoplastic fibromas are rare, benign, locally aggressive bone tumors, which arise primarily in patients younger than 30 years old. Historically, even with greater functional loss, en bloc or wide resection of the tumors to prevent local recurrence has been the method of choice in treatment. This article discusses the presentation of a 10-year-old male who presented with a mass in the distal forearm, after reporting difficulty in pronation and supination. The patient was ultimately treated with wide resection and allo-arthrodesis with allograft. Post-operatively, the patient has exhibited excellent recovery, including normal range of motion at the shoulder and elbow, and ability to perform all activities of daily livings despite reduced grip strength compared with the contralateral side.

  17. Epithelial Dysplasia in Ameloblastic Fibrosarcoma Arising from Recurrent Ameloblastic Fibroma in a 26-Year-Old Iranian Man

    Science.gov (United States)

    Mohsenifar, Zhaleh; Behrad, Samira; Abbas, Fatemeh Mashhadi

    2015-01-01

    Patient: Male, 26 Final Diagnosis: Ameloblastic fibrosarcoma Symptoms: Swelling Medication: — Clinical Procedure: Hemimandibulectomy Specialty: Dentistry Objective: Rare disease Background: Ameloblastic fibrosarcoma (AFS) is a rare malignant odontogenic tumor with a mesenchymal component, showing sarcomatous features and epithelial nests resembling ameloblastic fibroma (AF). Case Report: We report a case of AFS showing epithelial dysplasia arising in a recurrent AF in the left mandible after 3 years in a 26-year-old man, which is regarded as an uncommon histopathologic finding in AFS. We also emphasize the comprehensive clinical, radiographic, and histopathologic evaluation, and immunohistochemical staining of this patient. Conclusions: We conclude that it is important to consider malignancy alternations in the epithelial component of AFS, along with that of the mesenchymal component, to provide a proper diagnosis and treatment of recurrent AF. PMID:26289384

  18. Nucleotide sequence analysis of a unique near-terminal region of the tumorigenic poxvirus, Shope fibroma virus.

    Science.gov (United States)

    Massung, R F; McFadden, G; Moyer, R W

    1992-11-01

    Shope fibroma virus (SFV), a tumorigenic poxvirus, has a DNA genome of approximately 160 kb. Previous DNA sequence analysis of SFV has been mainly limited to the terminal inverted repetitions (about 12 kb at each end of the genome) and immediately adjacent regions. We have sequenced a 4 kb fragment located approximately 20 kb from the right-terminal hairpin. Within this region three complete and two partial open reading frames (ORFs) have been identified. Each of the putative polypeptides has sequence similarity to one or more previously identified poxvirus or cellular proteins, with homology to protein kinases, erythrocyte ankyrin and a vaccinia virus virulence-related protein (ORF N1L). The potential significance of these gene products with regard to the phenotype of SFV is discussed.

  19. Cemento-ossifying fibroma occurring in an elderly patient. A case report and a review of literature.

    Science.gov (United States)

    Dalghous, Abdulbaset; Alkhabuli, Juma O

    2007-06-01

    Cemento-ossifying fibromas (COF) are benign lesions affecting the jaws and other craniofacial bones. They commonly affect adults between the third and fourth decade of life. Radiographically, they appear as well-defined unilocular or multilocular intraosseous masses, commonly in the premolar/molar region of the mandible. The lesion is invariably encapsulated and of mixed radiolucent densities. The tumour may grow quite extensively, thus the term aggressive is some times applied. Their clinical, radiographical and histopathological features and those of fibro-osseous lesions are overlapping and may cause confusion in classification, diagnosis, and treatment. The histopathology is composed of fibrous tissues with calcified structures resembling bone or cementum. Surgical enucleation or resection is the treatment of choice. They are insensitive to radiotherapy and recurrences are uncommon. This case report presents a case of COF in 70 years old female patient that was asymptomatic. Clinically, there was an expansion of the buccal plate but not the lingual plate of the right mandible. The covering mucosa was normal and there was no tenderness or paraesthesia. Radiographically, the lesion extends superio-inferiory from the alveolar ridge to the area of inferior dental canal and mesiodistally from the premolar region to the retro-molar area. The lesion was of mixed radiolucent densities. The patient was followed up periodically for 5 years without any treatment. The patient continued to be asymptomatic with minimum changes. Occurrence of cemento-ossifying fibroma in patients over 60 years of age is unusual and had not been reported. The clinical, radiographic, histopathology and literature review are discussed.

  20. Who Does Extra-Credit Work in Introductory Science Courses?

    Science.gov (United States)

    Moore, Randy

    2005-01-01

    On the first day of classes, 81% of students in an introductory biology course claimed that they would submit extra-credit work if given the opportunity. When given two chances for extra-credit work, fewer than one-fourth of students submitted one or both assignments. Students who submitted extra-credit work were more likely to attend class,…

  1. Infantile fibrosarcoma successfully treated with chemotherapy, with occurrence of calcifying aponeurotic fibroma and pleomorphic/spindled celled lipoma at the site 12 years later.

    Science.gov (United States)

    DeComas, Amalia M; Heinrich, Stephen D; Craver, Randall

    2009-06-01

    The treatment of infantile fibrosarcoma has traditionally been wide resection. Chemotherapy has been investigated as an adjuvant and primary treatment in cases in which surgery would cause unacceptable morbidity. Recurrences normally occur within a year of completion of the chemotherapy and display the same histology. We present a child with an infantile fibrosarcoma of the elbow, successfully treated with chemotherapy alone, who developed a calcifying aponeurotic fibroma and a spindle cell/pleomorphic lipoma at the tumor site 12 years later.

  2. Twisted ovarian fibroma with high signal intensity on T1-weighted MR image: a new sign of torsion of ovarian tumors?

    Energy Technology Data Exchange (ETDEWEB)

    Minutoli, F.; Blandino, A.; Gaeta, M.; Pandolfo, I. [Inst. of Radiologic Sciences, University of Messina (Italy); Lentini, M. [Dept. of Human Pathology, University of Messina (Italy)

    2001-07-01

    Torsion of ovarian tumors is often difficult to diagnose, because of non-specific clinical, laboratory, and imaging findings. We report a case of twisted ovarian fibroma whose main characteristic was the presence of large areas of high signal intensity on both T1- and T2-weighted MR images due to the passive congestion of the mass. This previously unreported finding should be considered a sign of ovarian torsion and may facilitate prompt surgical intervention. (orig.)

  3. Mandibular ossifying fibroma and compound odontoma:a case report%下颌骨骨化纤维瘤并发组合性牙瘤1例

    Institute of Scientific and Technical Information of China (English)

    张丽娜; 申婷; 牛好曼; 耿宁; 汤亚玲; 陈宇

    2016-01-01

    A case diagnosed as ossifying fibroma and compound odontoma in the mandible was reported. The clinicopathological features, diagnosis, and treatment were discussed with the literature review.%本文报道1例左下颌骨骨化纤维瘤并发组合性牙瘤,并结合相关的文献对其临床病理特征及诊断治疗进行讨论。

  4. Extra-adrenal Pheochromocytoma in an Adolescent

    Directory of Open Access Journals (Sweden)

    Abdullah, Ibrahim

    2011-05-01

    Full Text Available A 17-year-old male with symptoms of headache and diaphoresis presented to the emergency department. He had eight months of noted hypertension attributed to medications. On arrival his blood pressure was 229/117mmHg, and he was ill-appearing. His blood pressure was managed aggressively, and he was diagnosed with extra-adrenal pheochromocytoma by computed tomography. He eventually underwent resection of the mass. Children with severe, symptomatic hypertension should be evaluated for pheochromocytoma. Although rare, it is curable. Failure to diagnose carries a high risk of morbidity and mortality. [West J Emerg Med. 2011;12(2:258-261.

  5. Aneurisma micotico de origem extra-vascular

    Directory of Open Access Journals (Sweden)

    Nelson Pires Ferreira

    1976-12-01

    Full Text Available É relatado o caso de uma paciente com três anos de idade portadora de oftalmoplegia completa unilateral e aneurisma da artéria carótida interna, em sua porção intra-cavernosa. A etiologia infecciosa extra-vascular, na vigência de tromboflebite de seio cavernoso, foi considerada. As informações da literatura são discutidas, sendo comentada a infrequência da patologia. A indicação de ligadura da artéria carótida interna, no tratamento desses aneurismas, merece ulterior comprovação.

  6. Enhanced gravitational scattering from large extra dimensions

    CERN Document Server

    Koyama, K; Wands, D; Koyama, Kazuya; Piazza, Federico; Wands, David

    2005-01-01

    We show that enhanced gravitational scattering on small scales (< 0.1 mm), which becomes possible in models with large extra dimensions, can establish statistical equilibrium between different particle species in the early Universe. Ultra-light WIMPs (e.g., axions) can be thermalized by such a mechanism and therefore are not viable CDM candidates in models with a fundamental Planck scale below about 10 TeV. More generally we note that the energy transfer rate is sensitive to trans-Planckian physics

  7. Radio communications with extra-terrestrial civilizations

    Science.gov (United States)

    Kotelnikov, V. A.

    1974-01-01

    Communications between civilizations within our galaxy at the present level of radio engineering is possible, although civilizations must begin to search for each other to achieve this. If an extra-terrestrial civilization possessing a technology at our level wishes to make itself known and will transmit special radio signals to do this, then it can be picked up by us at a distance of several hundreds of light years using already existing radio telescopes and specially built radio receivers. If it wishes, this civilization can also send us information without awaiting our answer.

  8. Extra-mammary findings in breast MRI

    Energy Technology Data Exchange (ETDEWEB)

    Rinaldi, Pierluigi; Costantini, M.; Belli, P.; Giuliani, M.; Bufi, E.; Fubelli, R.; Distefano, D.; Romani, M.; Bonomo, L. [Catholic University - Policlinic A. Gemelli, Department of Bio-Imaging and Radiological Sciences, Rome (Italy)

    2011-11-15

    Incidental extra-mammary findings in breast Magnetic Resonance Imaging (MRI) may be benign in nature, but may also represent a metastasis or another important lesion. We aimed to analyse the prevalence and clinical relevance of these unexpected findings. A retrospective review of 1535 breast MRIs was conducted. Only axial sequences were reassessed. Confirmation examinations were obtained in all cases. 285 patients had a confirmed incidental finding, which were located in the liver (51.9%), lung (11.2%), bone (7%), mediastinal lymph nodes (4.2%) or consisted of pleural/pericardial effusion (15.4%). 20.4% of incidental findings were confirmed to be malignant. Positive predictive value for MRI to detect a metastatic lesion was high if located within the bone (89%), lymph nodes (83%) and lung (59%), while it was low if located within the liver (9%) or if it consisted of pleural/pericardial effusion (6%). The axial enhanced sequence showed superior sensitivity to unenhanced images in detecting metastatic lesions, especially if only smaller ({<=}10 mm.) lesions were considered. The prevalence of metastatic incidental extra-mammary findings is not negligible. Particular attention should be to incidental findings located within the lung, bone and mediastinal lymph nodes. (orig.)

  9. Neutrino Mass Models in Extra Dimensions

    CERN Document Server

    Ng, J N

    2003-01-01

    Neutrinos play a crucial role in many areas of physics from very short distances to astrophysics and cosmology. It is a long held believe that they are good probes of physics at the GUT scale. Recent developments have made it clear that they can also be of fundamental importance for the physics of extra dimensions if these exist. Here we pedagogically review the construction of neutrino mass models in extra dimensions within the brane world scenarios. These models are usually nontrivial generalizations of their four dimensional counterparts. We describe the theoretical tools that have been forged and the new perpectives gained in this rapidly developing area. In particular we discuss the issues involve in building models without the use of right-handed singlets. It is very difficult to directly test the origin of neutrino masses in different models be it in four or more dimensions. We point out that different models give very different indirect signatures in the TeV region and in precision measurements.

  10. Neptune migration model with one extra planet

    CERN Document Server

    Yeh, Lun-Wen; 10.1016/j.icarus.2009.06.008

    2009-01-01

    We explore conventional Neptune migration model with one additional planet of mass at 0.1-2.0 Me. This planet inhabited in the 3:2 mean motion resonance with Neptune during planet migration epoch, and then escaped from the Kuiper belt when Jovian planets parked near the present orbits. Adding this extra planet and assuming the primordial disk truncated at about 45 AU in the conventional Neptune migration model, it is able to explain the complex structure of the observed Kuiper belt better than the usual Neptune migration model did in several respects. However, numerical experiments imply that this model is a low-probability event. In addition to the low probability, two features produced by this model may be inconsistent with the observations. They are small number of low-inclination particles in the classical belt, and the production of a remnant population with near-circular and low-inclination orbit within a = 50-52 AU. According to our present study, including one extra planet in the conventional Neptune ...

  11. Exploring extra dimensions with scalar waves

    CERN Document Server

    Jones-Smith, Katherine; Verostek, Michael

    2016-01-01

    This paper provides a pedagogical introduction to the physics of extra dimensions focussing on the ADD, Randall-Sundrum and DGP models. In each of these models, the familiar particles and fields of the standard model are assumed to be confined to a four dimensional space-time called the brane; the brane is a slice through a higher dimensional space-time called the bulk. The geometry of the ADD, Randall-Sundrum and DGP space-times is described and the relation between Randall-Sundrum and Anti-de-Sitter space-time is explained. The necessary differential geometry background is introduced in an appendix that presumes no greater mathematical preparation than multivariable calculus. The ordinary wave equation and the Klein-Gordon equation are briefly reviewed followed by an analysis of the propagation of scalar waves in the bulk in all three extra-dimensional models. We also calculate the scalar field produced by a static point source located on the brane for all three models. For the ADD and Randall-Sundrum model...

  12. Dynamical Electroweak Symmetry Breaking from Extra Dimensions

    CERN Document Server

    Hashimoto, M; Yamawaki, K; Hashimoto, Michio; Tanabashi, Masaharu; Yamawaki, Koichi

    2003-01-01

    We study the dynamical electroweak symmetry breaking (DEWSB) in the $D (=6,8,...)$-dimensional bulk with compactified extra dimensions. We identify the critical binding strength for triggering the DEWSB, based on the ladder Schwinger-Dyson equation. In the top mode standard model with extra dimensions, where the standard model gauge bosons and the third generation of quarks and leptons are put in the bulk, we analyze the most attractive channel (MAC) by using renormalization group equations (RGEs) of (dimensionless) bulk gauge couplings and determine the effective cutoff where the MAC coupling exceeds the critical value. We then find that the top-condensation can take place for D=8. Combining RGEs of top-Yukawa and Higgs-quartic couplings with compositeness conditions, we predict the top mass, $m_t=173-180$ GeV, and the Higgs mass, $m_H=181-211$ GeV, for D=8, where we took the universal compactification scale $1/R = 1-100$ TeV.

  13. Dynamical Electroweak Symmetry Breaking from Extra Dimensions

    Science.gov (United States)

    Hashimoto, Michio; Tanabashi, Masaharu; Yamawaki, Koichi

    2003-08-01

    We study the dynamical electroweak symmetry breaking (DEWSB) in the D(= 6, 8, ⋯)-dimensional bulk with compactified extra dimensions. We identify the critical binding strength for triggering the DEWSB, based on the ladder Schwinger-Dyson equation. In the top mode standard model with extra dimensions, where the standard model gauge bosons and the third generation of quarks and leptons are put in the bulk, we analyze the most attractive channel (MAC) by using renormalization group equations (RGEs) of (dimensionless) bulk gauge couplings and determine the effective cutoff where the MAC coupling exceeds the critical value. We then find that the top-condensation can take place for D = 8. Combining RGEs of top-Yukawa and Higgs-quartic couplings with compositeness conditions, we predict the top mass, mt = 173 - 180 GeV, and the Higgs mass, mH = 181 - 211 GeV, for D = 8, where we took the universal compactification scale 1/R = 1 - 100 TeV.

  14. Extra-Galactic Diffuse Interstellar Bands

    Science.gov (United States)

    Cox, N.; Ehrenfreund, Pascale; Kaper, Lex; Spaans, Marco; Foing, Bernard

    Diffuse Interstellar Bands (DIBs) have been observed ubiquitously along many sight-lines probing the interstellar medium of the Milky Way. Despite extensive efforts, their carrier(s) have not yet been identified, although they are very likely of a carbonaceous nature and reside in the gas phase. Possible candidates include, but are not limited to, polycyclic aromatic hydro- carbons (PAHs), fullerenes and carbon chains. To advance our understanding of DIB behaviour and thus DIB carrier properties we need to study environments inherently different from those observed in the Milky Way. Only recent advances in instrumentation and telescope capabilities are providing us with new exciting possibilities for extra-galactic DIB research. We present here a selection of our recent observational results for (extra)-galactic DIBs in the Local Group and beyond. In particular, DIBs in the Magellanic Clouds and in the spiral galaxy NGC1448. These first results show surprising similarities between certain DIB profiles as well as differences in DIB behaviour. Understanding diffuse cloud chemistry, in particular with respect to complex (carbonaceous) molecules, is crucial to any DIB carrier identification. In this respect, external galaxies offer a unique window as they exhibit local interstellar conditions (such as metallicity, UV-field and gas-to-dust ratio) very different from those observed in the Milky Way. We discuss briefly the effect of metallicity and the gas-to-dust ratio on the physi-chemical properties of diffuse clouds and the subsequent effects on the PAH charge state distribution and the DIB carriers.

  15. [Extra-articular manifestations of seronegative spondylarthritis].

    Science.gov (United States)

    Cammelli, Daniele

    2006-05-01

    Seronegative spondylarthritis are frequently characterised by extra-articular manifestations. They are frequently in recurrent uveitis. Between the cutaneous manifestations should be mentioned erythema nodosum, typical of inflammatory bowel diseases, and keratoderma blenorrhagicum, in the Reiter's syndrome. Cardiac complications in ankylosing spondylitis (AS) include aortic valvular regurgitation and arrhythmia and, more rarely, mitral valvulopathy, cardiomyopathy and pericarditis. Pulmonary involvement in AS includes ventilatory restrictive syndrome and fibro-bullous disease of the apex. Vertebral osteoporosis is a very important extra-articular manifestation because of the possibility of spontaneous fractures of the vertebrae. Central neurological manifestations include medullary compression from cervical sub-luxation while the most important peripheral involvements are lumbar stenosis and the cauda equina syndrome. Type AA amyloidosis is a rare late complication of the AS, possible cause of death especially in patients with aggressive disease. Kidney complications can be observed as consequences of prolonged anti-inflammatory therapy, but the most frequent renal complications are amyloidosis and mesangial IgA segmental and focal glomerulonephritis.

  16. Gauge symmetries emerging from extra dimensions

    Science.gov (United States)

    Chkareuli, J. L.; Kepuladze, Z.

    2016-09-01

    We argue that extra dimensions with a properly chosen compactification scheme could be a natural source for emergent gauge symmetries. Actually, some proposed vector field potential terms or polynomial vector field constraints introduced in five-dimensional Abelian and non-Abelian gauge theory are shown to smoothly lead to spontaneous violation of an underlying 5D spacetime symmetry and generate pseudo-Goldstone vector modes as conventional 4D gauge boson candidates. As a special signature, there appear, apart from conventional gauge couplings, some properly suppressed direct multiphoton (multiboson, in general) interactions in emergent QED and Yang-Mills theories whose observation could shed light on their high-dimensional nature. Moreover, in emergent Yang-Mills theories an internal symmetry G also occurs spontaneously broken to its diagonal subgroups once 5D Lorentz violation happens. This breaking originates from the extra vector field components playing a role of some adjoint scalar field multiplet in the 4D spacetime. So, one naturally has the Higgs effect without a specially introduced scalar field multiplet. Remarkably, when being applied to grand unified theories (GUTs) this results in a fact that the emergent GUTs generically appear broken down to the Standard Model just at the 5D Lorentz violation scale M .

  17. The Universe’s extra bits

    CERN Multimedia

    CERN Bulletin

    2010-01-01

    Parallel universes, unknown forms of matter, extra dimensions….This is not cheap science fiction but very concrete physics theories that the scientists are trying to confirm with the LHC and other ongoing experiments. Although it's enough to make us dream about going to a parallel world for the weekend, let’s keep our feet firmly on the ground and try to work out what all these things really are…   Given the astonishing fact that 96% of the Universe is actually unknown, we can think of filling it with all sorts of weird and exotic things. Extra dimensions and parallel universes may indeed be real, that is, their existence is accepted by a large community of scientists who have worked out mathematical models and physical constraints. “The idea of a fifth dimension was first introduced by Kaluza and Klein at the beginning of the last century in an attempt to unify gravity and electromagnetism”, confirms Ignatios Antoniadis from CERN’s Th...

  18. The CT manifestations of ovarian fibroma and fibrothecoma%12例卵巢纤维瘤和泡膜纤维瘤的CT表现

    Institute of Scientific and Technical Information of China (English)

    张见增; 秦明伟

    2011-01-01

    目的 分析卵巢纤维瘤和泡膜纤维瘤的CT表现特点,以提高诊断准确率.方法 回顾分析12例经手术病理证实的卵巢纤维瘤和泡膜纤维瘤的临床特点和CT表现.结果 (1)12例肿瘤中,卵巢纤维瘤5例,泡膜纤维瘤7例.(2)12例肿瘤均为单侧,左侧7例,右侧5例.(3)CT表现:卵巢纤维瘤为实性,较大时可有浅分叶;泡膜纤维瘤可为实性或囊实性,囊性病变区多为单房,囊壁厚薄均匀与实性区相延续.所有病变边缘清楚,强化不明显.结论 卵巢纤维瘤和泡膜纤维瘤的CT表现有一定特征性.%Objective To analyse the CT manifestations of ovarian fibromas and fibrothecomas and to improve the accuracy rate of the diagnosis. Methods The clinical and CT characteristics of the 12 cases with pathologically confirmed ovarian fibroma or fibrothecoma were reviewed. Results ( 1 ) Of the 12 cases, 5 were fibromas and 7 were fibrothecomas. (2)All the cases were unilateral, 5 were in the right and 7 were in the left. (3)On CT imaging,fibromas were solid and with shallow leaflet in big tumors. Fibrothecomas were solid or cystic-solid; the cystic part of every tumor was single, and the cystic walls were commonly uniform thickness and were extension of the solid part. All the tumors had clear borders; and had not obvious effect in contrast enhancement. Conclusion There are affirmative characteristics of ovarian fibromas and fibrothecomas on CT imaging.

  19. 鼻窦骨化纤维瘤23例临床分析%Clinical analysis of 23 patients with ossifying fibroma of paranasal sinuses

    Institute of Scientific and Technical Information of China (English)

    唐正一; 张龙城; 全超坤; 钟海林; 杨建均

    2013-01-01

    目的:探讨鼻窦骨化纤维瘤的临床特点及治疗方案.方法:回顾性分析我院收治的23例鼻窦骨化纤维瘤患者的临床资料.根据病变部位和范围,采用鼻侧切开及改良鼻侧切开术10例,鼻内镜下手术8例,上颌窦根治术入路手术4例,冠状切口颅骨切开手术1例.结果:除鼻内镜下2例为部分切除外,其余均彻底切除,术后病理检查均证实为骨化纤维瘤.23例患者随访20例,失访3例,随访时间6个月~19年.18例无复发,2例复发后再次手术.结论:早期发现、CT检查、选择适当的术式及尽早彻底切除病灶是治疗该病、改善预后的关键.%Objective:To investigate the clinical features and treatment options of ossifying fibroma of paranasal sinuses.Method:A retrospective evaluation of twenty-three patients with ossifying fibroma of paranasal sinuses was presented.The choice of surgical operations on ossifying fibroma of paranasal sinuses was mainly decided by the location and area of ossifying fibroma.Radical operations were performed in twenty-one patients,ten of them through a lateral rhinotomy approach,eight through nasal endoscopic approach,four through Caldwell-Luc approach,one through coronal approach.Result:Two patients were performed partial resection by nasal endoscopic surgery.Diagnoses of all cases were confirmed by pathology.All patients outcomes were successful,no serious complication from the surgical technique occurred.Twenty cases were followed-up for six months to nineteen years,Two patients recurred.Conclusion:Earlier diagnosis,CT scan,proper surgery,and radical resection are the keys to the treatment of ossifying fibroma of paranasal sinuses.

  20. An analysis of desmoplastic fibroma of bone%骨促结缔组织增生性纤维瘤的临床病理观察

    Institute of Scientific and Technical Information of China (English)

    哈英娣; 李宁; 刘斌

    2009-01-01

    目的:了解骨促结缔组织增生性纤维瘤的临床病理.方法:收集骨促结缔组织增生性纤维瘤1例和6例腹壁外韧带样纤维瘤病的临床资料.手术切除组织HE染色光镜观察.涂胶切片做Vimentin,Desmin,NF,S100蛋白的单克隆标记.结果:骨促结缔组织增生性纤维瘤的组织学改变和免疫组织化学标记与腹壁外韧带样纤维瘤病相似,临床症状和影像学改变与骨样骨瘤相似.结论:骨促结缔组织增生性纤维瘤易发生于青年男性,病理才能将其确诊,有复发的可能.%Objective:To investigate the clinicopathological features of desmoplastic fibroma of bone.Methods:By means of histological,and immunohistochemical studies,the clinical and pathological features of one case of desmoplastic fibroma of bone was analyzed and comparing with 6 cases of soft tissue desmoid type fibromatosis.Results:Patient of desmoplastic fibroma of bone was a young man.The tumor was located at the tibia.Microscopic sections showed a uniform appearance of long,slender,spindle-shaped fibroblasts arranged in bands and faxcicles and surrounded by large amounts of cllagen. Local recurrence following excision occurred in two cases of soft tissue desmoid type fibromatosis.In both desmoplastic fibroma of bone and soft tissue desmoid type fibromatosis immunohistochemical expression of vimentin was positive,and S100 protein,desmin and NF were negative.Conclusion:Desmoplastic fibroma of bone may be recurred.The diagnosis was based on histological observation and immunohistochemical staining.

  1. Fibroma condromixóide da coluna torácica: Relato de caso e revisão da literatura Chondromyxoid fibroma compressing the spinal cord: case report and review of the literature

    Directory of Open Access Journals (Sweden)

    Manoel Baldoino Leal Filho

    1995-12-01

    Full Text Available Os autores relatam caso de compressão medular torácica por lesão da quinta articulação costovertebral à direita. O diagnóstico pré-operatório, com mielotomografia, foi de processo expansivo intrarraquidiano extradural ao nível de T5. Feita a abordagem cirúrgica por laminectomia, com ressecção apenas da lesão intrarraquidiana. O diagnóstico de fibroma condromixóide somente foi definido com o estudo histopatológico. A paciente teve importante melhora neurológica. Decidiu-se pelo acompanhamento clínico e radiológico. Após dois anos houve recidiva do processo para dentro do canal raquidiano. Desta vez, foi realizada abordagem posterolateral à direita, por costotransversectomia e retirada da lesão. O diagnóstico histopatológico foi o mesmo. A paciente evoluiu com melhora neurológica e está sendo feito o seguimento há dois anos. Chamamos a atenção para a raridade do caso e discutimos a conduta.A case of chondromyxoid fibroma (CMF arising from the Sth right costovertebral junction and spreading into spinal canal causing spinal cord compression is presented. A myelotomography revealed a complete block at T5 level. The patient underwent a decompressive laminectomy with removal of an epidural tumor. This specimen was sent for pathological examination and interpreted as a CMF. The patient had a neurological improvement, post operative MRI revealed a spinal cord free of compression, and we decided on the follow up of the case. Two years later there was reccurrence of the tumor. A posterolateral access by costotransversectomy was made and the lesion was resected. The patient had a neurological improvement which persists on the follow up (two years, at present. Clinical, radiologic and histologic findings, surgical management and recurrence are discussed. The pertinent literature is reviewed.

  2. 软骨黏液样纤维瘤的影像诊断%Imaging diagnosis of chondromyxoid fibroma

    Institute of Scientific and Technical Information of China (English)

    于静红; 陶美丽; 张云风; 李伟; 孙瑞芬

    2015-01-01

    目的 分析软骨黏液样纤维瘤的影像表现特点,提高诊断正确率.方法 回顾性分析经手术病理证实的8例软骨黏液样纤维瘤的X线、CT及MRI表现.结果 8例均发生于长管状骨.X线上病灶为卵圆形偏侧透亮区,边界清楚,边缘硬化,6例内部见粗大纵行骨嵴或粗大网状分隔.CT上病灶为边界清楚、边缘硬化,1例见小点状高密度钙化影.MRI上T1WI为低或中低信号,T2WI上为较高信号,1例病灶边缘有等T1、稍高T2信号影围绕.2例静脉注射钆喷酸葡胺后T1WI扫描病灶呈弥漫强化,其中1例周围见较明显线状强化.结论 软骨黏液样纤维瘤在影像表现上有一定特点,结合X线、CT及MRI可与其他影像表现相似的骨肿瘤进行鉴别.%Objective To analyze the imaging manifestations of chondromyxoid fibroma,so as to improve diagnostic accuracy.Methods The X-ray,CT and MRI manifestations of 8 cases with chondromyxoid fibroma confirmed by surgical pathology were analyzed retrospectively.Results All of 8 cases were in the long tubular bones.X-ray showed oval,well defined,eccentric,radiolucent lesion with surrounding sclerosis.The thick dense bony or coarse reticular septation were seen in 6 cases.CT scan showed osteolytic,surrounding sclerosis,and 1 case with foci of calcification.MRI images showed a low or medium signal on T1WI,high signal on T2WI,1 case with a equal T1WI and slight high T2WI signal intensity peripheral rim around.Two cases with diffused enhancement on T1WI after intravenous injection of gapentetate acid meglumine injection and a peripheral liner enhancement in 1 case.Conclusion Chondromyxoid fibroma has certain imaging characteristics,but should be combined with X-ray,CT and MRI to differentiate from other bone tumors with similar imaging manifestations.

  3. Higgs Phenomenology of Minimal Universal Extra Dimensions

    Directory of Open Access Journals (Sweden)

    Kakizaki Mitsuru

    2012-06-01

    Full Text Available The minimal model of Universal Extra Dimensions (MUED is briefly reviewed. We explain how the cross-sections for Higgs production via gluon fusion and decay into photons are modified, relative the the Standard Model (SM values, by KK particles running in loops, leading to an enhancement of the gg → h → γγ and gg → h → W+W− cross-sections. ATLAS and CMS searches for the SM Higgs in these channels are reinterpreted in the context of MUED and used to place new limits on the MUED parameter space. Only a small region of between 1 and 3 GeV around mh = 125 GeV for 500 GeV < R−1 < 1600 GeV remains open at the 95 % confidence level.

  4. Celulitis por cuerpo extraño

    OpenAIRE

    2016-01-01

    Las infecciones de la piel y el tejido celular subcutáneo surgen como un grupo importante de afecciones con una alta morbilidad en edades pediátricas, generalmente relacionada con traumatismo y cuerpos extraños. Se presenta el caso de una escolar femenina de 6 años de edad, con síntomas y signos clínicos que sugieren celulitis en el muslo derecho,  por su evolución tórpida se le realizó el estudio ultrasonográfico que confirmó el diagnóstico etiológico de una celulitis secundaria a un traumat...

  5. Black holes, cosmology and extra dimensions

    CERN Document Server

    Bronnikov, Kirill A

    2013-01-01

    Assuming foundational knowledge of special and general relativity, this book guides the reader on issues surrounding black holes, wormholes, cosmology, and extra dimensions. Its first part is devoted to local strong field configurations (black holes and wormholes) in general relativity and the most relevant of alternative theories: scalar-tensor, f(R) and multidimensional theories. The second part is on cosmology, including inflation and a unified description of the whole evolution of the universe. The third part concerns multidimensional theories of gravity and contains a number of original results obtained by the authors. Expository work is conducted for a mechanism of symmetries and fundamental constants formation, while the original approach to nonlinear multidimensional gravity that is able to construct a unique perspective describing different phenomena is highlighted. Much of the content is new in book publications, because it was previously found only in journal publications, e.g. regarding regular bl...

  6. Phenomenology of symmetry breaking from extra dimensions

    Energy Technology Data Exchange (ETDEWEB)

    Alfaro, Jorge [Facultad de Fisica, Pontificia Universidad Catolica de Chile, Casilla 306, Santiago 22 (Chile); Broncano, Alicia [Max Planck Institute for Physics, Foehringer Ring 6, 80805 Munich (Germany); Belen Gavela, Maria [Departamento de Fisica Teorica and Instituto de Fisica Teorica, Universidad Autonoma de Madrid, Cantoblanco, E-28049 Madrid (Spain); Rigolin, Stefano [Departamento de Fisica Teorica and Instituto de Fisica Teorica, Universidad Autonoma de Madrid, Cantoblanco, E-28049 Madrid (Spain); Salvatori, Matteo [Departamento de Fisica Teorica and Instituto de Fisica Teorica, Universidad Autonoma de Madrid, Cantoblanco, E-28049 Madrid (Spain)

    2007-01-15

    Motivated by the electroweak hierarchy problem, we consider theories with two extra dimensions in which the four-dimensional scalar fields are components of gauge boson in full space. We explore the Nielsen-Olesen instability for SU(N) on a torus, in the presence of a magnetic background. A field theory approach is developed, computing explicitly the minimum of the complete effective potential, including tri-linear and quartic couplings and determining the symmetries of the stable vacua. We also develop appropriate gauge-fixing terms when both Kaluza-Klein and Landau levels are present and interacting, discussing the interplay between the possible six and four dimensional choices. The equivalence between coordinate dependent and constant Scherk-Schwarz boundary conditions - associated to either continuous or discrete Wilson lines - is analyzed.

  7. Dynamic Extra Buses Scheduling Strategy in Public Transport

    Directory of Open Access Journals (Sweden)

    Bin Yu

    2015-06-01

    Full Text Available This paper presents a dynamic extra buses scheduling strategy to improve the transit service of transit routes. In this strategy, in order to decide when to dispatch an extra bus, the service reliability of transit route is assessed firstly. A model aimed at maximizing the benefit of the extra buses scheduling strategy is constructed to determine how many stops extra buses need to skip from the terminal to accommodate passengers at the following stops. A heuristic algorithm is defined and implemented to estimate the service reliability of transit route and to optimize the initial stop of extra buses scheduling strategy. Finally, the strategy is tested on two examples: a simple and a real-life transit route in the Dalian city in China. The results show that the extra buses scheduling strategy based on terminal stops with a reasonable threshold can save 8.01% waiting time of passengers.

  8. Cosmologically safe QCD axion as a present from extra dimension

    Directory of Open Access Journals (Sweden)

    Masahiro Kawasaki

    2015-11-01

    Full Text Available We propose a QCD axion model where the origin of PQ symmetry and suppression of axion isocurvature perturbations are explained by introducing an extra dimension. Each extra quark–antiquark pair lives on branes separately to suppress PQ breaking operators. The size of the extra dimension changes after inflation due to an interaction between inflaton and a bulk scalar field, which implies that the PQ symmetry can be drastically broken during inflation to suppress undesirable axion isocurvature fluctuations.

  9. Cosmologically safe QCD axion as a present from extra dimension

    Energy Technology Data Exchange (ETDEWEB)

    Kawasaki, Masahiro [Institute for Cosmic Ray Research, The University of Tokyo, Kashiwa, Chiba 277-8582 (Japan); Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Yamada, Masaki, E-mail: yamadam@icrr.u-tokyo.ac.jp [Institute for Cosmic Ray Research, The University of Tokyo, Kashiwa, Chiba 277-8582 (Japan); Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan); Yanagida, Tsutomu T. [Kavli IPMU (WPI), UTIAS, The University of Tokyo, Kashiwa, Chiba 277-8583 (Japan)

    2015-11-12

    We propose a QCD axion model where the origin of PQ symmetry and suppression of axion isocurvature perturbations are explained by introducing an extra dimension. Each extra quark–antiquark pair lives on branes separately to suppress PQ breaking operators. The size of the extra dimension changes after inflation due to an interaction between inflaton and a bulk scalar field, which implies that the PQ symmetry can be drastically broken during inflation to suppress undesirable axion isocurvature fluctuations.

  10. Compact extra dimensions in cosmologies with f(T) structure

    CERN Document Server

    Fiorini, Franco; Vasquez, Yerko

    2013-01-01

    The presence of compact extra dimensions in cosmological scenarios in the context of f(T)-like gravities is discussed. For the case of toroidal compactifications, the analysis is performed in an arbitrary number of extra dimensions. Spherical topologies for the extra dimensions are then carefully studied in six and seven spacetime dimensions, where the proper vielbein fields responsible for the parallelization process are found.

  11. Science with the EXTraS Project: Exploring the X-ray Transient and variable Sky

    CERN Document Server

    De Luca, A; Tiengo, A; D'Agostino, D; Watson, M G; Haberl, F

    2015-01-01

    The EXTraS project (Exploring the X-ray Transient and variable Sky) will characterise the temporal behaviour of the largest ever sample of objects in the soft X-ray range (0.1-12 keV) with a complex, systematic and consistent analysis of all data collected by the European Photon Imaging Camera (EPIC) instrument onboard the ESA XMM-Newton X-ray observatory since its launch. We will search for, and characterize variability (both periodic and aperiodic) in hundreds of thousands of sources spanning more than nine orders of magnitude in time scale and six orders of magnitude in flux. We will also search for fast transients, missed by standard image analysis. Our analysis will be completed by multiwavelength characterization of new discoveries and phenomenological classification of variable sources. All results and products will be made available to the community in a public archive, serving as a reference for a broad range of astrophysical investigations.

  12. Analysis of GNAS mutations in cemento-ossifying fibromas and cemento-osseous dysplasias of the jaws.

    Science.gov (United States)

    Patel, Milan M; Wilkey, Jonathan F; Abdelsayed, Rafik; D'Silva, Nisha J; Malchoff, Carl; Mallya, Sanjay M

    2010-05-01

    It is well established that fibrous dysplasia (FD) is caused by mutations of the Arg(201) codon of the GNAS gene. However, the role of GNAS mutation in the pathogenesis of cement-osseous dysplasias (COD) and cemento-ossifying fibromas (COF) is not fully known. In this study, we examined COD and COF for mutations at the Arg(201) codon of the GNAS gene. The study sample included formalin-fixed, paraffin-embedded tissue blocks from 8 COF and 24 COD. We used 2 PCR-RFLP methods to detect mutations at the Arg(201) codon of the GNAS gene. Mutations at the Arg(201) codon of the GNAS gene were not present in any of the COD and COF examined. GNAS mutations do not play a role in the pathogenesis of COD and COF. This highlights a clear molecular distinction between FD and other histologically similar fibro-osseous lesions of the jaws. Copyright (c) 2010 Mosby, Inc. All rights reserved.

  13. Calcifying aponeurotic fibroma of the finger in an elderly patient: CT and MRI findings with pathologic correlation

    Science.gov (United States)

    NISHIO, JUN; INAMITSU, HIDEAKI; IWASAKI, HIROSHI; HAYASHI, HIROYUKI; NAITO, MASATOSHI

    2014-01-01

    Calcifying aponeurotic fibroma (CAF) is a rare, locally aggressive fibroblastic lesion that occurs predominantly in the distal extremities of children and adolescents. In the present study, a case of pathologically proven CAF arising in the right little finger of a 69-year-old woman is presented. Physical examination revealed a firm, immobile, non-tender mass. Plain radiographs showed a faintly calcified soft tissue mass without bone involvement and computed tomography scans clearly demonstrated the presence of the lesion. Magnetic resonance imaging revealed that the lesion exhibited low to intermediate signal intensity on T1-weighted images and heterogeneous high signal intensity with small foci of low signal intensity on T2-weighted spectral presaturation with inversion recovery images. Contrast-enhanced fat-suppressed T1-weighted images demonstrated intense heterogeneous enhancement throughout the mass. The patient underwent an excisional biopsy. Histologically, the tumor showed a biphasic pattern, composed of a moderately cellular fibromatosis-like component and irregular calcified areas with polygonal epithelioid cells. There has been no evidence of local recurrence four months following surgery. To the best of our knowledge, this case report describes the oldest patient with this condition. PMID:25120611

  14. Extra relativistic degrees of freedom without extra particles using Planck data

    CERN Document Server

    Mastache, Jorge

    2013-01-01

    A recent number of analysis of cosmological data have shown indications for the presence of extra radiation beyond the standard model at equality and nucleosynthesis epoch, which has been usually interpreted as an effective number of neutrinos, Neff > 3.046. In this work we establish the theoretical basis for a particle physics-motivated model (Bound Dark Matter, BDM) which explain the need of extra radiation. The BDM model describes dark matter particles which are relativistic at a scale below aac due to non-perturbative methods, as protons and neutrons do, this process is described by a time dependent equation of state, w_bdm(a). We compute the range of values of the BDM model, xc=ac*vc, that explain the values obtain for the 4He at BBN and Neff at equality. Combining different analysis we conclude that this may happen in xc = 5.01 (^{+6.01}_{-5.01}) x 10^{-5} with a vc = 0.56 \\pm 0.39. We conclude that we can account for the apparent extra radiation Nex using phase transition in the dark matter with a time...

  15. Fibroma desmoplásico de mandíbula asociado a esclerosis tuberosa: Revisión de la literatura y presentación de un caso Desmoplastic fibroma of the jaw associated with tuberous sclerosis: Literature review and case report

    Directory of Open Access Journals (Sweden)

    M. Acosta Feria

    2008-04-01

    Full Text Available La esclerosis tuberosa es una anomalía congénita del desarrollo embrionario que se transmite de forma autosómica dominante caracterizada por la presencia por trastornos neurológicos, cutáneos o dermatológicos, y retraso mental. Se pueden afectar otros órganos y sistemas, y dar manifestaciones orofaciales. La lesión a nivel del esmalte dental constituye la lesión intraoral más frecuente. Rara vez se pueden encontrar lesiones óseas en los maxilares. El fibroma desmoplásico es un infrecuente tumor fibroso intraóseo localmente agresivo de lento crecimiento, que se asocia muy rara vez a la esclerosis tuberosa. Presentamos el caso clínico de un paciente de 33 años afecto de esclerosis tuberosa con una lesión en la mandíbula diagnosticada como fibroma desmoplásico. Se discuten los métodos diagnósticos, presentación clínica y tratamiento.Tuberous sclerosis is a congenital anomaly of embryonic development with an autosomal dominant inheritance. It is characterized by the presence of neurologic and dermatologic disorders and mental retardation. It can affect other organs and systems and produce orofacial manifestations. Dental enamel defects are the most frequent intraoral lesion. Bone lesions rarely occur in the upper jaw. Desmoplastic fibroma is an infrequent, slow-growing, locally aggressive intraosseous fibrous tumor that rarely is associated with tuberous sclerosis. We report the clinical case of a 33-year-old man with tuberous sclerosis and a jaw lesion diagnosed as desmoplastic fibroma. The diagnostic methods, clinical presentation, and treatment are discussed.

  16. Analysis of Misdiagnosis of Ossifying Fibroma of the Temporal Bone%颞骨骨化纤维瘤误诊分析

    Institute of Scientific and Technical Information of China (English)

    李红霞; 李晓明; 单珊; 杨泽垠

    2015-01-01

    Objective To summarize the clinical features, diagnostic and differential diagnostic measures of ossifying fibroma of the temporal bone, analyze the cause of misdiagnose, improve the understanding of the disease, and avoid misdiag-nosis and mistreatment. Methods Retrospective analysis of the clinical data of a misdiagnosed case of ossifying fibroma of the temporal bone in our division was carried out. Results The patient was admitted for right ear pain associated with hearing loss for more than two years and tinnitus for four months. The patient had been diagnosed with otitis media in another local hospital. After 6 months of anti-infection and glucocorticoid treatment, improvement of symptoms was not significant. In our hospital, the patient was suspected as having lesions, combining with the history, clinical signs and medical examination. The right temporal bone resection, and infratemporal fossa tumor resection, temporalis muscle flap transfer for repair were per-formed. Postoperative pathology confirmed temporal bone ossifying fibroma. Postoperative hearing improved significantly and tinnitus disappeared. Conclusion The prophase clinical manifestations of temporal bone ossifying fibroma lack specificity and tend to be missed diagnosis and misdiagnosed. Improved awareness of temporal bone ossifying fibroma,careful examinations and system checks may reduce or avoid misdiagnosis and mistreatment of temporal bone ossifying fibroma.%目的:总结颞骨骨化纤维瘤的临床特点、诊断及鉴别诊断措施,提高对其认识,减少误诊误治。方法回顾性分析我科收治的曾误诊为中耳炎的颞骨骨化纤维瘤1例的临床资料。结果患者因右耳疼痛伴听力下降2年余,耳鸣4个月以颞骨肿瘤收住入院。当地医院曾诊断为中耳炎,给予抗感染及糖皮质激素治疗15 d,症状改善不明显,入我院后结合病史、临床特征及医技检查结果,拟诊为颞骨占位性病变,行右侧颞骨部分切除、

  17. 乳腺单纯型黏液腺癌与纤维腺瘤的MRI表现%MRI Findings of Simple Mucinous Carcinoma and Fibroma of Breast

    Institute of Scientific and Technical Information of China (English)

    李莉; 程流泉; 李洪福; 索峰

    2011-01-01

    目的 总结乳腺单纯型黏液腺癌与纤维腺瘤的MRI 表现的差异,寻找鉴别诊断的依据.资料与方法比较经手术病理证实的8 例(16 灶)单纯型黏液腺癌、15 例(16 灶)纤维腺瘤的形态学特征、血液动力学及表观扩散系数(ADC 值).结果 单纯型黏液腺癌7 例(7/8 )表现为单发肿块型,1 例(1/8)表现为多灶肿块;纤维腺瘤表现为肿块型14 灶(14/16),非肿块型2 灶(2/16);单纯型黏液腺癌增强曲线13 灶呈Ⅰ型,3灶呈Ⅱ型;纤维腺瘤6 灶呈Ⅰ型,8 灶呈Ⅱ型,2 灶呈Ⅲ型;b 值=1 000s/mm2 时黏液腺癌ADC 值(2.05±0.31)×10-3 mm2/s 高于纤维腺瘤(1.34±0.31)×10-3 mm2/s,差异有统计学意义(P <0.05).结论 单纯型黏液腺癌和纤维腺瘤的MRI 表现在形态学和动态增强曲线上有交叉,但是黏液腺癌成像特征性的高ADC 值具有鉴别诊断价值.%Purpose To summarize the different MRI manifestations of simple mucmous carcinoma and fibroma of breast, and to investigate the basis of differential diagnosis. Materials andMethods 8 patients with 16 simple mucinous carcinomas and 15 patients with 16 fibromas confirmed by pathology were respectively reviewed. Morphology, hemodynamic features and apparent diffusion coefficient (ADC) value of the lesions were analysed. Results Seven of eight cases of mucinous carcinoma had single mass and one case had multiple masses. Fourteen fibromas cases showed a mass and two cases showed a non-mass-like lesions. The dynamic intensity curve of thirteen mucinous carcinomas had persistent time intensity curve (Type Ⅰ) and the other 3 lesions had plateau type (Type Ⅱ). For the dynamic intensity curve of fibromas, 6 lesions had persistent type, 8 with plateau type and 2 with washout type (Type Ⅲ ). The ADC values of mucinous carcinoma and fibroma were (2.05±0.31) × 10-3 mm2/s and (1.34 ±0.31) × 10-3 mm2/s, respectively, when using b = 1 000 s/mm2. There was statistical difference (P < 0.05). Conclusion

  18. Higgs Pair Production in Models with Universal Extra Dimensions

    CERN Document Server

    de Sandes, Hiroshi

    2007-01-01

    In this letter we study the process of gluon fusion into a pair of Higgs bosons in a model with one universal extra dimension. We find that the contributions from the extra top quark Kaluza-Klein excitations lead to a Higgs pair production cross section that can be significantly altered compared to the Standard Model value for small values of the compactification scale.

  19. 29 CFR 541.604 - Minimum guarantee plus extras.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Minimum guarantee plus extras. 541.604 Section 541.604 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION, DEPARTMENT OF LABOR REGULATIONS... SALES EMPLOYEES Salary Requirements § 541.604 Minimum guarantee plus extras. (a) An employer may...

  20. Direct Detection of Extra-Solar Comets is Possible

    OpenAIRE

    Jura, M.

    2005-01-01

    The dust tails of comets similar to Hale-Bopp can scatter as much optical light as does the Earth. Space-based observatories such as the Terrestrial Planet Finder or Darwin that will detect extra-solar terrestrial planets also will be able to detect extra-solar comets.