WorldWideScience

Sample records for external ion injection

  1. Liquid metal ion source assembly for external ion injection into an electron string ion source (ESIS)

    Energy Technology Data Exchange (ETDEWEB)

    Segal, M. J., E-mail: mattiti@gmail.com [iThemba LABS, P.O. Box 722, Somerset West 7130 (South Africa); University of Cape Town, Rondebosch, Cape Town 7700 (South Africa); Bark, R. A.; Thomae, R. [iThemba LABS, P.O. Box 722, Somerset West 7130 (South Africa); Donets, E. E.; Donets, E. D.; Boytsov, A.; Ponkin, D.; Ramsdorf, A. [Joint Institute for Nuclear Research, Joloit-Curie 6, 141980 Dubna, Moscow Region (Russian Federation)

    2016-02-15

    An assembly for a commercial Ga{sup +} liquid metal ion source in combination with an ion transportation and focusing system, a pulse high-voltage quadrupole deflector, and a beam diagnostics system has been constructed in the framework of the iThemba LABS (Cape Town, South Africa)—JINR (Dubna, Russia) collaboration. First, results on Ga{sup +} ion beam commissioning will be presented. Outlook of further experiments for measurements of charge breeding efficiency in the electron string ion source with the use of external injection of Ga{sup +} and Au{sup +} ion beams will be reported as well.

  2. Development of a Kingdon ion trap system for trapping externally injected highly charged ions.

    Science.gov (United States)

    Numadate, Naoki; Okada, Kunihiro; Nakamura, Nobuyuki; Tanuma, Hajime

    2014-10-01

    We have developed a Kingdon ion trap system for the purpose of the laboratory observation of the x-ray forbidden transitions of highly charged ions (HCIs). Externally injected Ar(q+) (q = 5-7) with kinetic energies of 6q keV were successfully trapped in the ion trap. The energy distribution of trapped ions is discussed in detail on the basis of numerical simulations. The combination of the Kingdon ion trap and the time-of-flight mass spectrometer enabled us to measure precise trapping lifetimes of HCIs. As a performance test of the instrument, we measured trapping lifetimes of Ar(q+) (q = 5-7) under a constant number density of H2 and determined the charge-transfer cross sections of Ar(q+)(q = 5, 6)-H2 collision systems at binary collision energies of a few eV. It was confirmed that the present cross section data are consistent with previous data and the values estimated by some scaling formula.

  3. Negative ion source with external RF antenna

    Science.gov (United States)

    Leung, Ka-Ngo; Hahto, Sami K.; Hahto, Sari T.

    2007-02-13

    A radio frequency (RF) driven plasma ion source has an external RF antenna, i.e. the RF antenna is positioned outside the plasma generating chamber rather than inside. The RF antenna is typically formed of a small diameter metal tube coated with an insulator. An external RF antenna assembly is used to mount the external RF antenna to the ion source. The RF antenna tubing is wound around the external RF antenna assembly to form a coil. The external RF antenna assembly is formed of a material, e.g. quartz, which is essentially transparent to the RF waves. The external RF antenna assembly is attached to and forms a part of the plasma source chamber so that the RF waves emitted by the RF antenna enter into the inside of the plasma chamber and ionize a gas contained therein. The plasma ion source is typically a multi-cusp ion source. A converter can be included in the ion source to produce negative ions.

  4. Orthogonal ion injection apparatus and process

    Science.gov (United States)

    Kurulugama, Ruwan T; Belov, Mikhail E

    2014-04-15

    An orthogonal ion injection apparatus and process are described in which ions are directly injected into an ion guide orthogonal to the ion guide axis through an inlet opening located on a side of the ion guide. The end of the heated capillary is placed inside the ion guide such that the ions are directly injected into DC and RF fields inside the ion guide, which efficiently confines ions inside the ion guide. Liquid droplets created by the ionization source that are carried through the capillary into the ion guide are removed from the ion guide by a strong directional gas flow through an inlet opening on the opposite side of the ion guide. Strong DC and RF fields divert ions into the ion guide. In-guide orthogonal injection yields a noise level that is a factor of 1.5 to 2 lower than conventional inline injection known in the art. Signal intensities for low m/z ions are greater compared to convention inline injection under the same processing conditions.

  5. Ion Plasma Responses to External Electromagnetic Fields

    NARCIS (Netherlands)

    Naus, H.W.L.

    2010-01-01

    The response of ion plasmas to external radiation fields is investigated in a quantum mechanical formalism.We focus on the total electric field within the plasma. For general bandpass signals three frequency regions can be distinguished in terms of the plasma frequency. For low frequencies, the exte

  6. The SNS External Antenna H- Ion Source

    Energy Technology Data Exchange (ETDEWEB)

    Welton, Robert F [ORNL; Stockli, Martin P [ORNL; Murray Jr, S N [ORNL; Crisp, Danny W [ORNL; Carmichael, Justin R [ORNL; Goulding, Richard Howell [ORNL; Han, Baoxi [ORNL; Pennisi, Terry R [ORNL; Santana, Manuel [ORNL

    2010-01-01

    The U.S. Spallation Neutron Source (SNS) is an accelerator-based, pulsed neutron-scattering facility, currently in the process of ramping up neutron production. In order to insure that we will meet our operational commitments as well as provide for future facility upgrades with high reliability, we have developed an RF-driven, H- ion source based on a ceramic aluminum nitride (AlN) plasma chamber [1]. This source is expected to be utilized by the SNS for neutron production starting in 2009. This report details the design of the production source which features an AlN plasma chamber, 2-layer external antenna, cooled-multicusp magnet array, Cs2CrO4 cesium system and a Molybdenum plasma ignition gun. Performance of the production source both on the SNS accelerator and SNS test stand is reported. The source has also been designed to accommodate an elemental Cs system with an external reservoir which has demonstrated unanalyzed beam currents up to ~100mA (60Hz, 1ms) on the SNS ion source test stand.

  7. Incoherent vertical ion losses during multiturn stacking cooling beam injection

    Science.gov (United States)

    Syresin, E. M.

    2014-07-01

    The efficiency of the multiturn ion injection with electron cooling depends on two parameters, namely, cooling efficiency and ion lifetime. The lifetime of freshly injected ions is usually shorter than the lifetime of strongly cooled stacked ions. Freshly injected ions are lost in the vertical direction because the vertical acceptance of the synchrotron is usually a few times smaller than the horizontal acceptance. Incoherent vertical losses of freshly injected ions arise from their multiple scattering by residual gas atoms and transverse diffusion caused by stack noise. Reduced ion lifetime limits the multiturn injection efficiency. Analytical estimations and BETACOOL-based numerical evaluations of the vertical ion losses during multiturn injection are presented in comparison with the experimental data obtained at the HIMAC synchrotron and the S-LSR storage ring.

  8. Multicusp ion source with external rf antenna for production of protons

    Science.gov (United States)

    Hahto, S. K.; Hahto, S. T.; Ji, Q.; Leung, K. N.; Wilde, S.; Foley, E. L.; Grisham, L. R.; Levinton, F. M.

    2004-02-01

    Proton beams are needed in neutral-beam injection for diagnostic development of an internal magnetic field measurement. High proton fraction, low axial energy spread, current density in excess of 30 mA/cm2, and a parallel ion beam with cw operation are the requirements for the ion source/extraction system. A multicusp-type ion source with an external rf antenna was constructed at Lawrence Berkeley National Laboratory. A proton fraction of 85% and proton current density of 32 mA/cm2 were achieved at 1.8 kW of rf power. Plasma parameters were measured with a rf compensated Langmuir probe.

  9. Simulation of ion beam injection and extraction in an EBIS

    Energy Technology Data Exchange (ETDEWEB)

    Zhao, L., E-mail: zhao@far-tech.com; Kim, J. S. [FAR-TECH, Inc., San Diego, California 92121 (United States)

    2016-02-15

    An example simulation of Au+ charge breeding using FAR-TECH’s integrated EBIS (electron beam ion source) modeling toolset is presented with the emphasis on ion beam injection and extraction. The trajectories of injected ions are calculated with PBGUNS (particle beam gun simulation) self-consistently by including the space charges from both ions and electrons. The ion beam, starting with initial conditions within the 100% acceptance of the electron beam, is then tracked by EBIS-PIC (particle-in-cell EBIS simulation code). In the trap, the evolution of the ion charge state distribution is estimated by charge state estimator. The extraction of charge bred ions is simulated with PBGUNS. The simulations of the ion injections show significant ion space charge effects on beam capture efficiency and the ionization efficiency.

  10. Simulation of ion beam injection and extraction in an EBIS

    Science.gov (United States)

    Zhao, L.; Kim, J. S.

    2016-02-01

    An example simulation of Au+ charge breeding using FAR-TECH's integrated EBIS (electron beam ion source) modeling toolset is presented with the emphasis on ion beam injection and extraction. The trajectories of injected ions are calculated with PBGUNS (particle beam gun simulation) self-consistently by including the space charges from both ions and electrons. The ion beam, starting with initial conditions within the 100% acceptance of the electron beam, is then tracked by EBIS-PIC (particle-in-cell EBIS simulation code). In the trap, the evolution of the ion charge state distribution is estimated by charge state estimator. The extraction of charge bred ions is simulated with PBGUNS. The simulations of the ion injections show significant ion space charge effects on beam capture efficiency and the ionization efficiency.

  11. Modification of SRIM-calculated dose and injected ion profiles due to sputtering, injected ion buildup and void swelling

    Science.gov (United States)

    Wang, Jing; Toloczko, Mychailo B.; Bailey, Nathan; Garner, Frank A.; Gigax, Jonathan; Shao, Lin

    2016-11-01

    In radiation effects on materials utilizing self-ion irradiations, it is necessary to calculate the local displacement damage level and ion injection profile because of the short distance that self-ions travel in a material and because of the strong variation of displacement rate with depth in a specimen. The most frequently used tool for this is the software package called Stopping and Range of Ions in Matter (SRIM). A SRIM-calculated depth-dependent dose level is usually determined under the implicit assumption that the target does not undergo any significant changes in volume during the process, in particular SRIM ignores the effect of sputtering, injected ions, and void swelling on the redistribution of the dose and injected ion profiles. This approach become increasingly invalid as the ion fluence reaches ever higher levels, especially for low energy ion irradiations. The original surface is not maintained due to sputter-induced erosion, while within the irradiated region of the specimen, injected ions are adding material, and if void swelling is occurring, it is creating empty space. An iterative mathematical treatment of SRIM outputs to produce corrected dose and injected ion profiles based on these phenomenon and without regard to diffusion is presented along with examples of differences between SRIM-calculated values and corrected values over a range of typical ion energies. The intent is to provide the reader with a convenient tool for more accurately calculating dose and injected ion profiles for heavy-ion irradiations.

  12. Ion Injection at Non-relativistic Collisionless Shocks

    CERN Document Server

    Caprioli, Damiano; Spitkovsky, Anatoly

    2014-01-01

    We use kinetic hybrid simulations (kinetic ions - fluid electrons) to characterize the fraction of ions that are accelerated to non-thermal energies at non-relativistic collisionless shocks. We investigate the properties of the shock discontinuity and show that shocks propagating almost along the background magnetic field (quasi-parallel shocks) reform quasi-periodically on ion cyclotron scales. Ions that impinge on the shock when the discontinuity is the steepest are specularly reflected. This is a necessary condition for being injected, but it is not sufficient. Also by following the trajectories of reflected ions, we calculate the minimum energy needed for injection into diffusive shock acceleration, as a function of the shock inclination. We construct a minimal model that accounts for the ion reflection from quasi-periodic shock barrier, for the fraction of injected ions, and for the ion spectrum throughout the transition from thermal to non-thermal energies. This model captures the physics relevant for i...

  13. Fifty Cases of External Humeral Epicondylitis Treated by Moxibustion and Point-injection

    Institute of Scientific and Technical Information of China (English)

    宋理萍

    2004-01-01

    Objective: To observe the therapeutic effects of moxibustion and point-injection on external humeral epicondylitis. Method: The disease is treated with the combined method of moxibustion and effect. The total effective rate was 96%. Conclusion: The combined method of moxibustion and point-injection is a cure indicated for external humeral epicondylitis.

  14. Rapid crystallization of externally produced ions in a Penning trap

    CERN Document Server

    Murboeck, T; Birkl, G; Noertershaeuser, W; Thompson, R C; Vogel, M

    2016-01-01

    We have studied the cooling dynamics, formation process and geometric structure of mesoscopic crystals of externally produced magnesium ions in a Penning trap. We present a cooling model and measurements for a combination of buffer gas cooling and laser cooling which has been found to reduce the ion kinetic energy by eight orders of magnitude from several hundreds of eV to micro-eV and below within seconds. With ion numbers of the order of 1000 to 100000, such cooling leads to the formation of ion Coulomb crystals which display a characteristic shell structure in agreement with theory of non-neutral plasmas. We show the production and characterization of two-species ion crystals as a means of sympathetic cooling of ions lacking a suitable laser-cooling transition.

  15. Ion injection optimization for a linear Paul trap to study intense beam propagation

    Directory of Open Access Journals (Sweden)

    Moses Chung

    2007-01-01

    Full Text Available The Paul Trap Simulator Experiment (PTSX is a linear Paul trap whose purpose is to simulate the nonlinear transverse dynamics of intense charged particle beam propagation in periodic-focusing quadrupole magnetic transport systems. Externally created cesium ions are injected and trapped in the long central electrodes of the PTSX device. In order to have well-matched one-component plasma equilibria for various beam physics experiments, it is important to optimize the ion injection. From the experimental studies reported in this paper, it is found that the injection process can be optimized by minimizing the beam mismatch between the source and the focusing lattice, and by minimizing the number of particles present in the vicinity of the injection electrodes when the injection electrodes are switched from the fully oscillating voltage waveform to their static trapping voltage.

  16. Possible role of external radial electric field on ion heating in an FRC

    Science.gov (United States)

    Gupta, Deepak; Trask, E.; Korepanov, S.; Granstedt, E.; Osin, D.; Roche, T.; Deng, B.; Beall, M.; Zhai, K.; TAE Team

    2016-10-01

    In C-2/C-2U FRCs, a radial electric field is applied by either plasma guns or biased electrodes inside the divertors, at both ends of the machine. The electric field plays an important role in stabilizing the FRC; thus, providing a favorable target condition to a neutral beam injection. In addition, it is also observed that the application of radial electric field may lead to a heating of ions. Radial profile of impurity ion emission, azimuthal velocity and temperature are measured under different configurations. The conditions and evidences of ion heating due to the electric field biasing will be presented and discussed. Radial momentum balance equation of oxygen impurity ions is used with these measurements to estimate the radial electric field profile. Parameters affecting the ion heating due to biasing will also be discussed with some correlations. The external radial electric field is planned to be applied by biased electrodes and plasma guns in C-2W inner/outer divertors.

  17. Modification of SRIM-calculated dose and injected ion profiles due to sputtering, injected ion buildup and void swelling

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Jing; Toloczko, Mychailo B.; Bailey, Nathan; Garner, Frank A.; Gigax, Jonathan; Shao, Lin

    2016-11-01

    In radiation effects on materials utilizing self-ion irradiations, it is necessary to calculate the local displacement damage level and ion injection profile because of the short distance that self-ions travel in a material and because of the strong variation of displacement rate with depth in a specimen. The most frequently used tool for this is the software package called Stopping and Range of Ions in Matter (SRIM). A SRIM-calculated depth-dependent dose level is usually determined under the implicit assumption that the target does not undergo any significant changes in volume during the process, in particular SRIM ignores the effect of sputtering, injected ions, and void swelling on the redistribution of the dose and injected atom profiles. This approach become increasingly invalid as the ion fluence reaches ever higher levels, especially for low energy ion irradiations. The original surface is not maintained due to sputter-induced erosion, while within the irradiated region of the specimen, injected ions are adding material, and if void swelling is occurring, it is creating empty space. An iterative mathematical treatment of SRIM outputs to produce corrected dose and injected atom profiles is presented along with examples differences between SRIM-calculated values and corrected values over a range of typical ion energies.

  18. Heavy Ion Injection Into Synchrotrons, Based On Electron String Ion Sources

    CERN Document Server

    Donets, E E; Syresin, E M

    2004-01-01

    A possibility of heavy ions injection into synchrotrons is discussed on the base of two novel ion sources, which are under development JINR during last decade: 1) the electron string ion source (ESIS), which is a modified version of a conventional electron beam ion source (EBIS), working in a reflex mode of operation, and 2) the tubular electron string ion source (TESIS). The Electron String Ion Source "Krion-2" (VBLHE, JINR, Dubna) with an applied confining magnetic field of 3 T was used for injection into the superconducting JINR synchrotron - Nuclotron and during this runs the source provided a high pulse intensity of the highly charged ion beams: Ar16+

  19. Ion channel recordings on an injection-molded polymer chip

    DEFF Research Database (Denmark)

    Tanzi, Simone; Matteucci, Marco; Christiansen, Thomas Lehrmann

    2013-01-01

    In this paper, we demonstrate recordings of the ion channel activity across the cell membrane in a biological cell by employing the so-called patch clamping technique on an injection-molded polymer microfluidic device. The findings will allow direct recordings of ion channel activity to be made u...

  20. Generation of Low Jitter Laser Diode Pulse With External Pulse Injection

    Institute of Scientific and Technical Information of China (English)

    Wang Yuncai; Olaf Reimann; Dieter Huhse; Dieter Bimberg

    2003-01-01

    One gain-switched laser diode(LD) was used as external injection seeding source, to reduce the timing jitter of another gain-switched LD, This technique can generate low jitter, frequency-free and wavelength tunable laser pulse.

  1. Improvements to the internal and external antenna H(-) ion sources at the Spallation Neutron Source.

    Science.gov (United States)

    Welton, R F; Dudnikov, V G; Han, B X; Murray, S N; Pennisi, T R; Pillar, C; Santana, M; Stockli, M P; Turvey, M W

    2014-02-01

    The Spallation Neutron Source (SNS), a large scale neutron production facility, routinely operates with 30-40 mA peak current in the linac. Recent measurements have shown that our RF-driven internal antenna, Cs-enhanced, multi-cusp ion sources injects ∼55 mA of H(-) beam current (∼1 ms, 60 Hz) at 65-kV into a Radio Frequency Quadrupole (RFQ) accelerator through a closely coupled electrostatic Low-Energy Beam Transport system. Over the last several years a decrease in RFQ transmission and issues with internal antennas has stimulated source development at the SNS both for the internal and external antenna ion sources. This report discusses progress in improving internal antenna reliability, H(-) yield improvements which resulted from modifications to the outlet aperture assembly (applicable to both internal and external antenna sources) and studies made of the long standing problem of beam persistence with the external antenna source. The current status of the external antenna ion source will also be presented.

  2. Stabilization of class-B broad-area lasers emission by external optical injection

    CERN Document Server

    Pakhomov, A V

    2016-01-01

    We theoretically examine the effect of external optical injection on the spatio-temporal dynamics of class-B broad-area lasers. We demonstrate that optical injection can efficiently stabilize the intrinsic transverse instabilities in such lasers associated with both the boundaries of the pumping area and with the bulk nonlinearities of the active medium. Stabilizing action of optical injection is shown to be closely related to the suppression of inherent relaxation oscillations behavior.

  3. Ion Source for Neutral beam injection meant for plasma and magnetic field diagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Vainionpaa, Jaakko Hannes; Leung, Ka Ngo; Gough, Richard A.; Kwan, Joe W.; Levinton, Fred

    2007-06-01

    At the Lawrence Berkeley National Laboratory (LBNL) a diagnostic neutral beam injection system for measuring plasma parameters, flow velocity, and local magnetic field is being developed. The systems is designed to have a 90 % proton fraction and small divergence with beam current at 5-6 A and a pulse length of {approx}1 s occurring once every 1-2 min. The ion source needs to generate uniform plasma over a large (8 cm x 5 cm) extraction area. For this application, we have compared RF driven multicusp ion sources operating with either an external or an internal antenna in similar ion source geometry. The ion beam will be made of an array of six sheet-shaped beamlets. The design is optimized using computer simulation programs.

  4. INJECTION OPTICS FOR THE JLEIC ION COLLIDER RING

    Energy Technology Data Exchange (ETDEWEB)

    Morozov, Vasiliy [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Derbenev, Yaroslav [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Lin, Fanglei [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Pilat, Fulvia C. [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Wei, Guohio [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Zhang, Yuhong [Thomas Jefferson National Accelerator Facility (TJNAF), Newport News, VA (United States); Nosochkov, Y. M. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Cai, Yunhai [SLAC National Accelerator Lab., Menlo Park, CA (United States); Sullivan, Michael K. [SLAC National Accelerator Lab., Menlo Park, CA (United States); Wang, M. H. [SLAC National Accelerator Lab., Menlo Park, CA (United States)

    2016-05-01

    The Jefferson Lab Electron-Ion Collider (JLEIC) will accelerate protons and ions from 8 GeV to 100 GeV. A very low beta function at the Interaction Point (IP) is needed to achieve the required luminosity. One consequence of the low beta optics is that the beta function in the final focusing (FF) quadrupoles is extremely high. This leads to a large beam size in these magnets as well as strong sensitivity to errors which limits the dynamic aperture. These effects are stronger at injection energy where the beam size is maximum, and therefore very large aperture FF magnets are required to allow a large dynamic aperture. A standard solution is a relaxed injection optics with IP beta function large enough to provide a reasonable FF aperture. This also reduces the effects of FF errors resulting in a larger dynamic aperture at injection. We describe the ion ring injection optics design as well as a beta-squeeze transition from the injection to collision optics.

  5. New ion source for KSTAR neutral beam injection system.

    Science.gov (United States)

    Kim, Tae-Seong; Jeong, Seung Ho; In, Sang-Ryul

    2012-02-01

    The neutral beam injection system (NBI-1) of the KSTAR tokamak can accommodate three ion sources; however, it is currently equipped with only one prototype ion source. In the 2010 and 2011 KSTAR campaigns, this ion source supplied deuterium neutral beam power of 0.7-1.6 MW to the KSTAR plasma with a beam energy of 70-100 keV. A new ion source will be prepared for the 2012 KSTAR campaign with a much advanced performance compared with the previous one. The newly designed ion source has a very large transparency (∼56%) without deteriorating the beam optics, which is designed to deliver a 2 MW injection power of deuterium beams at 100 keV. The plasma generator of the ion source is of a horizontally cusped bucket type, and the whole inner wall, except the cathode filaments and plasma grid side, functions as an anode. The accelerator assembly consists of four multi-circular aperture grids made of copper and four electrode flanges made of aluminum alloy. The electrodes are insulated using PEEK. The ion source will be completed and tested in 2011.

  6. Continuum Modeling of the Dynamics of Externally Injection-locked Coupled Oscillator Arrays

    Science.gov (United States)

    Pogorzelski, Ronald J.; Maccarini, Paolo F.; York, Robert A.

    1999-01-01

    Mutually injection-locked arrays of electronic oscillators provide a novel means of controlling the aperture phase of a phased-array antenna, thus achieving the advantages of spatial power combining while retaining the ability to steer the radiated beam. In a number of design concepts, one or more of the oscillators are injection locked to a signal from an external master-oscillator. The behavior of such a system has been analyzed by numerical solution of a system of nonlinear differential equations which, due to its complexity, yields limited insight into the relationship between the injection signals and the aperture phase. In this paper, we develop a continuum model, which results in a single partial differential equation for the aperture phase as a function of time. Solution of the equation is effected by means of the Laplace transformation and yields detailed information concerning the dynamics of the array under the influence of the external injection signals.

  7. Ion Acceleration at the Quasi-Parallel Shock: Injection Unveiled

    CERN Document Server

    Sundberg, Torbjörn; Burgess, David; Mazelle, Christian X

    2015-01-01

    Collisionless shocks are efficient particle accelerators. At Earth, ions with energies exceeding 100 keV are seen upstream of the bow shock when the magnetic geometry is quasi-parallel, and large-scale supernova remnant shocks can accelerate ions into cosmic rays energies. This energization is attributed to diffusive shock acceleration, however, for this process to become active the ions must first be sufficiently energized. How and where this initial acceleration takes place has been one of the key unresolved issues in shock acceleration theory. Using Cluster spacecraft observations, we study the signatures of ion reflection events in the turbulent transition layer upstream of the shock, and with the support of a hybrid simulation of the shock, we show that these reflection signatures are characteristic of the first step in the ion injection process. These reflection events develop in particular in the region where the trailing edge of large-amplitude upstream waves intercept the local shock ramp and the ups...

  8. External Second Gate-Fourier Transform Ion Mobility Spectrometry.

    Energy Technology Data Exchange (ETDEWEB)

    Tarver, Edward E., III

    2005-01-01

    Ion mobility spectrometry (IMS) is recognized as one of the most sensitive and versatile techniques for the detection of trace levels of organic vapors. IMS is widely used for detecting contraband narcotics, explosives, toxic industrial compounds and chemical warfare agents. Increasing threat of terrorist attacks, the proliferation of narcotics, Chemical Weapons Convention treaty verification as well as humanitarian de-mining efforts has mandated that equal importance be placed on the analysis time as well as the quality of the analytical data. (1) IMS is unrivaled when both speed of response and sensitivity has to be considered. (2) With conventional (signal averaging) IMS systems the number of available ions contributing to the measured signal to less than 1%. Furthermore, the signal averaging process incorporates scan-to-scan variations decreasing resolution. With external second gate Fourier Transform ion mobility spectrometry (FT-IMS), the entrance gate frequency is variable and can be altered in conjunction with other data acquisition parameters to increase the spectral resolution. The FT-IMS entrance gate operates with a 50% duty cycle and so affords a 7 to 10-fold increase in sensitivity. Recent data on high explosives are presented to demonstrate the parametric optimization in sensitivity and resolution of our system.

  9. Fast ion behavior during neutral beam injection in ATF

    Energy Technology Data Exchange (ETDEWEB)

    Wade, M.R.; Thomas, C.E.; Colchin, R.J.; Rome, J.A.; England, A.C.; Fowler, R.H. [Oak Ridge National Lab., TN (United States); Aceto, S.C. [Rensselaer Polytechnic Inst., Troy, NY (United States)

    1993-09-01

    In stellarators, single-particle confinement properties can be more complex than in their tokamak counterparts. Fast-ion behavior in tokamaks has been well characterized through an abundance of measurements on various devices and in general has been shown to be consistent with classical slowing-down theory, although anomalous ion behavior has been observed during intense beam injection in ISX-B, during fishbone instabilities in PDX, and in experiments on TFR. In contrast, fast ion behavior in stellarators is not as wel established experimentally with the primary experiments to date focusing o near-perpendicular or perpendicular neutral beam injection (NBI) on the Wendelstein 7-A stellarator (91 and Heliotron-E. This paper addresses fast-ion confinement properties in a large-aspect-ratio, moderate-shear stellarator, the Advanced Toroidal Facility, during tangential NBI. The primary data used in this study are the experimentally measured energy spectra of charge-exchange neutrals escaping from the plasma, using a two-dimensional scanning neutral particle analyzer. This diagnostic method is well established, having been used on several devices since the early 1970`s. Various aspects of fast-ion behavior are investigated by comparing these data with computed theoretical spectra based on energeticion distributions derived from the fastion Fokker-Planck equation. Ion orbits are studied by computer orbit following, by the computation of J* surfaces, and by Monte Carlo calculations.

  10. Control of light polarization using optically spin-injected vertical external cavity surface emitting lasers

    Energy Technology Data Exchange (ETDEWEB)

    Frougier, J., E-mail: julien.frougier@thalesgroup.com; Jaffrès, H.; Deranlot, C.; George, J.-M. [Unité Mixte de Physique CNRS-Thales and Université Paris Sud 11, 1 av. Fresnel, 91767 Palaiseau (France); Baili, G.; Dolfi, D. [Thales Research and Technology, 1 av. Fresnel, 91767 Palaiseau (France); Alouini, M. [Institut de Physique de Rennes, 263 Avenue Général Leclerc, 35042 Rennes (France); Sagnes, I. [Laboratoire de Photonique et de Nanostructures, Route de Nozay, 91460 Marcoussis (France); Garnache, A. [Institut d' électronique du Sud CNRS UMR5214, Université Montpellier 2 Place Eugene Bataillon, 34095 Montpellier (France)

    2013-12-16

    We fabricated and characterized an optically pumped (100)-oriented InGaAs/GaAsP multiple quantum well Vertical External Cavity Surface Emitting Laser (VECSEL). The structure is designed to allow the integration of a Metal-Tunnel-Junction ferromagnetic spin-injector for future electrical injection. We report here the control at room temperature of the electromagnetic field polarization using optical spin injection in the active medium of the VECSEL. The switching between two highly circular polarization states had been demonstrated using an M-shaped extended cavity in multi-modes lasing. This result witnesses an efficient spin-injection in the active medium of the LASER.

  11. Multicusp ion source with external RF antenna for production of H- ions

    Science.gov (United States)

    Kalvas, T.; Hahto, S. K.; Vainionpää, J. H.; Leung, K. N.; Wilde, S. B.; Mandrillon, P.

    2007-08-01

    A multicusp ion source with modular design was developed at LBNL for production of H- ions. The source consists of a front plate, two multicusp front chambers, a quartz flange with external 3-loop RF antenna and a rear multicusp chamber. The source has LaB6 sputtering target at the rear chamber to lower the work function of the surfaces by coating them with LaB6 and an external cesium oven on the front plate. The front plate also has an integrated collar and filter magnets to cool plasma near the extraction. The collar also enables the use of cesium and LaB6 surface effects. The rear chamber is equipped with three vacuum feed-throughs for operation with two gases and a pressure measurement. Current density of over 10 mA/cm2 of H- has been measured with e/I- ratio being ˜100 when the source was operated with only 1000 W of cw RF power. Negative ion production was enhanced using cesium, Xe gas mixing and LaB6 deposition to the source surfaces. When the front plate with filter magnets is removed, the source produces large amounts of H+. Current density of 110 mA/cm2 with 1800 W RF power at 2.3 Pa source pressure was measured with over 90 % atomic species. A long operation lifetime is excepted as the external RF antenna is not exposed to plasma.

  12. Review of MEVVA ion source performance for accelerator injection

    Energy Technology Data Exchange (ETDEWEB)

    Brown, I.G.; Godechot, X. (Lawrence Berkeley Lab., CA (USA)); Spaedtke, P.; Emig, H.; Rueck, D.M.; Wolf, B.H. (Gesellschaft fuer Schwerionenforschung mbH, Darmstadt (Germany, F.R.))

    1991-05-01

    The Mevva (metal vapor vacuum arc) ion source provides high current beams of multiply-charged metal ions suitable for use in heavy ion synchrotrons as well as for metallurgical ion implantation. Pulsed beam currents of up to several amperes can be produced at ion energies of up to several hundred keV. Operation has been demonstrate for 48 metallic ion species: Li, C, Mg, Al, Si, Ca, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, Ge, Sr, Y, Zr, Nb, Mo, Pd, Ag, Cd, In, Sn, Ba, La, Ce, Pr, Nd, Sm, Gd, Dy, Ho, Er, Yb, Hf, Ta, W, Ir, Pt, Au, Pb, Bi, Th and U. When the source is operated optimally the rms fractional beam noise can be as low as 7% of the mean beam current; and when properly triggered the source operates reliably and reproducibly for many tens of thousands of pulses without failure. In this paper we review the source performance referred specifically to its use for synchrotron injection. 15 refs., 3 figs.

  13. Ion channel recordings on an injection-molded polymer chip.

    Science.gov (United States)

    Tanzi, Simone; Matteucci, Marco; Christiansen, Thomas Lehrmann; Friis, Søren; Christensen, Mette Thylstrup; Garnaes, Joergen; Wilson, Sandra; Kutchinsky, Jonatan; Taboryski, Rafael

    2013-12-21

    In this paper, we demonstrate recordings of the ion channel activity across the cell membrane in a biological cell by employing the so-called patch clamping technique on an injection-molded polymer microfluidic device. The findings will allow direct recordings of ion channel activity to be made using the cheapest materials and production platform to date and with the potential for very high throughput. The employment of cornered apertures for cell capture allowed the fabrication of devices without through holes and via a scheme comprising master origination by dry etching in a silicon substrate, electroplating in nickel and injection molding of the final part. The most critical device parameters were identified as the length of the patching capillary and the very low surface roughness on the inside of the capillary. The cross-sectional shape of the orifice was found to be less critical, as both rectangular and semicircular profiles seemed to have almost the same ability to form tight seals with cells with negligible leak currents. The devices were functionally tested using human embryonic kidney cells expressing voltage-gated sodium channels (Nav1.7) and benchmarked against a commercial state-of-the-art system for automated ion channel recordings. These experiments considered current-voltage (IV) relationships for activation and inactivation of the Nav1.7 channels and their sensitivity to a local anesthetic, lidocaine. Both IVs and lidocaine dose-response curves obtained from the injection-molded polymer device were in good agreement with data obtained from the commercial system.

  14. Simulation of stripping injection into HITFiL with carbon ion

    Institute of Scientific and Technical Information of China (English)

    XIE Xiu-Cui; SONG Ming-Tao; ZHANG Xiao-Hu

    2013-01-01

    Stripping injection is one of the crucial stages in the accumulation process of the hadron therapy synchrotron HITFiL (Heavy Ion Therapy Facility in Lanzhou).In order to simulate the stripping injection process of carbon ions for HITFiL,the interactions between carbon ions and foil has been studied,and simulated with a code developed by ourselves.The optimized parameters of the injecting beam and the scheme of the injection system have been presented for HITFiL.

  15. Simulation of stripping injection into HITFiL with carbon ion

    Science.gov (United States)

    Xie, Xiu-Cui; Song, Ming-Tao; Zhang, Xiao-Hu

    2013-09-01

    Stripping injection is one of the crucial stages in the accumulation process of the hadron therapy synchrotron HITFiL (Heavy Ion Therapy Facility in Lanzhou). In order to simulate the stripping injection process of carbon ions for HITFiL, the interactions between carbon ions and foil has been studied, and simulated with a code developed by ourselves. The optimized parameters of the injecting beam and the scheme of the injection system have been presented for HITFiL.

  16. Simulation of stripping injection into HITFiL with carbon ion

    CERN Document Server

    Xie, Xiucui; Zhang, Xiaohu

    2013-01-01

    Stripping injection is one of the crucial stages in the accumulation process of the hadron therapy synchrotron HITFiL (Heavy Ion Therapy Facility in Lanzhou). In order to simulate the stripping injection process of carbon ions for HITFiL, the interactions between carbon ions and foil has been studied, and simulated with a code developed by ourselves .The optimized parameters of the injecting beam and the scheme of the injection system have been presented for HITFiL.

  17. Improvements to the internal and external antenna H{sup −} ion sources at the Spallation Neutron Source

    Energy Technology Data Exchange (ETDEWEB)

    Welton, R. F., E-mail: welton@ornl.gov; Han, B. X.; Murray, S. N.; Pennisi, T. R.; Pillar, C.; Santana, M.; Stockli, M. P. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, Tennessee 37830-6471 (United States); Dudnikov, V. G. [Muons, Inc., 552 N. Batavia Avenue, Batavia, Illinois 60510 (United States); Turvey, M. W. [Villanova University, 800E. Lancaster Ave, Villanova, Pennsylvania 19085 (United States)

    2014-02-15

    The Spallation Neutron Source (SNS), a large scale neutron production facility, routinely operates with 30–40 mA peak current in the linac. Recent measurements have shown that our RF-driven internal antenna, Cs-enhanced, multi-cusp ion sources injects ∼55 mA of H{sup −} beam current (∼1 ms, 60 Hz) at 65-kV into a Radio Frequency Quadrupole (RFQ) accelerator through a closely coupled electrostatic Low-Energy Beam Transport system. Over the last several years a decrease in RFQ transmission and issues with internal antennas has stimulated source development at the SNS both for the internal and external antenna ion sources. This report discusses progress in improving internal antenna reliability, H{sup −} yield improvements which resulted from modifications to the outlet aperture assembly (applicable to both internal and external antenna sources) and studies made of the long standing problem of beam persistence with the external antenna source. The current status of the external antenna ion source will also be presented.

  18. Gamma-Ray Burst Afterglows with Energy Injection: Homogeneous VersusWind External Media

    Institute of Scientific and Technical Information of China (English)

    王伟; 戴子高

    2001-01-01

    Assuming an adiabatic evolution of a gamma-ray burst (GRB) fireball interacting with an external medium,we calculate the hydrodynamics of the fireball with an energy injection from a strongly magnetic millisecond pulsar through magnetic dipole radiation, and obtain the light curve of the optical afterglow from the fireball by synchrotron radiation. The results are given both for an homogeneous external medium and for a wind ejected by GRB progenitor. Our calculations are also available in both ultra-relativistic and non-relativistic phases.Furthermore, the observed R-band light curve of GRB000301C can be well fitted in our model, which might provide a probe of the properties of GRB progenitors.

  19. Evaluation of a novel PTFE material for separation and preconcentration of trace levels of metal ions in sequential injection (SI) and sequential injection lab-on-valve (SI-LOV) systems interfaced with detection by ETAAS

    DEFF Research Database (Denmark)

    Long, Xiangbao; Chomchoei, Roongrat; Gała, Piotr

    The operational characteristics of a novel PTFE bead material, granular Algoflon®, used for separation and preconcentration of metal ions via adsorption of on-line generated non-charged metal complexes, were evaluated in a sequential injection (SI) system furnished with an external packed column...

  20. External-field shifts in precision spectroscopy of hydrogen molecular ions

    Energy Technology Data Exchange (ETDEWEB)

    Bakalov, Dimitar, E-mail: dbakalov@inrne.bas.bg [INRNE, Bulgarian Academy of Sciences (Bulgaria); Korobov, Vladimir [Joint Institute for Nuclear Research (Russian Federation); Schiller, Stephan [Heinrich-Heine-Universitat Dusseldorf, Institut fur Experimentalphysik (Germany)

    2015-08-15

    The Effective Hamiltonian of the hydrogen molecular ions is a convenient tool for the evaluation of the shift of the energy levels of the ro-vibrational states and the frequencies of the transitions between them, due to external electric and magnetic fields. Using the Effective Hamiltonian, composite frequencies of suppressed susceptibility to external fields are constructed.

  1. Injection to the pick-up ion regime from high energies and induced ion power laws

    CERN Document Server

    Fahr, H -J; Verscharen, D

    2008-01-01

    Though pick-up ions (PUIs) are a well known phenomenon in the inner heliosphere, their phase-space distribution nevertheless is a theoretically unsettled problem. Especially the question of how pick-up ions form their suprathermal tails, extending to far above their injection energies, still now is unsatistactorily answered. Though Fermi-2 velocity diffusion theories have revealed that such tails are populated, they nevertheless show that resulting population densities are much less than seen in observations showing power-laws with a velocity index of ``-5''. We first investigate here, whether or not observationally suggested power-laws can be the result of a quasi-equilibrium state between suprathermal ions and magnetohydrodynamic turbulences in energy exchange with eachother. We demonstrate that such an equilibrium cannot be established. We furthermore show that Fermi-2 type energy diffusion in the outer heliosphere is too inefficient to determine the shape of the distribution function there. As we can show...

  2. Fluctuations in the intensity of a single-frequency injection laser with an external dispersion cavity

    Energy Technology Data Exchange (ETDEWEB)

    Bogatov, A.P.; Eliseev, P.G.; Kobildzhanov, O.A.; Madgazin, V.R.; Okhotnikov, O.G.

    1986-12-01

    Studies of the intensity fluctuations of a single-frequency injection laser have revealed that they are caused by beats between the coherent field and superluminescent spontaneous radiation. A drop in the fluctuation level with an increase in the laser output power in the region of developed laser generation is observed experimentally as well as a relative shift in the frequencies of the superluminescent modes of the external cavity; this shift is a function of lasing power. This behavior is explained by a mechanism of nonlinear interaction of fields in the active region of the laser diode. With significant laser output power (about 6 mW), the fluctuation level exceeds the shot noise level by no more than 4 dB. 12 references.

  3. External bone remodeling after injectable calcium-phosphate cement in benign bone tumor: two cases in the hand.

    Science.gov (United States)

    Ichihara, S; Vaiss, L; Acciaro, A L; Facca, S; Liverneaux, P

    2015-12-01

    Bone remodeling commonly occurred after fracture and curettage benign bone tumor. A lot of previous articles reported "internal" trabecular bone remodeling. There were no previous clinical reports about "external" cortical bone remodeling. We present here 2 clinical cases of "external" bone remodeling after injectable calcium-phosphate in benign bone tumor in the hand. In two cases of benign bone tumor, we performed complete removal of the tumor and immediate filling of the metacarpal bone with injectable calcium-phosphate cement Arexbone(®) from the mechanical viewpoint. With respect to the shape of the calcium-phosphate, by using an injection-type, calcium-phosphate is adhered uniformly to the bone cortex by injecting, remodeling has been promoted. After 5 and 8years, both cases were no recurrences, and the shape of the metacarpal looked close to the contralateral side. These findings supposed to be concerned with potential self-healing and self-protection mechanism in human body.

  4. Investigation of charge injection and transport behavior in multilayer structure consisted of ferromagnetic metal and organic polymer under external fields

    Science.gov (United States)

    Zhao, Hua; Meng, Wei-Feng

    2017-10-01

    In this paper a five layer organic electronic device with alternately placed ferromagnetic metals and organic polymers: ferromagnetic metal/organic layer/ferromagnetic metal/organic layer/ferromagnetic metal, which is injected a spin-polarized electron from outsides, is studied theoretically using one-dimensional tight binding model Hamiltonian. We calculated equilibrium state behavior after an electron with spin is injected into the organic layer of this structure, charge density distribution and spin polarization density distribution of this injected spin-polarized electron, and mainly studied possible transport behavior of the injected spin polarized electron in this multilayer structure under different external electric fields. We analyze the physical process of the injected electron in this multilayer system. It is found by our calculation that the injected spin polarized electron exists as an electron-polaron state with spin polarization in the organic layer and it can pass through the middle ferromagnetic layer from the right-hand organic layer to the left-hand organic layer by the action of increasing external electric fields, which indicates that this structure may be used as a possible spin-polarized charge electronic device and also may provide a theoretical base for the organic electronic devices and it is also found that in the boundaries between the ferromagnetic layer and the organic layer there exist induced interface local dipoles due to the external electric fields.

  5. The selectivity of different external binding sites for quaternary ammonium ions in cloned potassium channels.

    Science.gov (United States)

    Jarolimek, W; Soman, K V; Brown, A M; Alam, M

    1995-09-01

    Tetraethylammonium (TEA) is thought to be the most effective quaternary ammonium (QA) ion blocker at the external site of K+ channels, and small changes to the TEA ion reduce its potency. To examine the properties of the external QA receptor, we applied a variety of QA ions to excised patches from human embryonic kidney cells or Xenopus oocytes transfected with the delayed rectifying K+ channels Kv 2.1 and Kv 3.1. In outside-out patches of Kv 3.1, the relative potencies were TEA > tetrapropylammonium (TPA) > tetrabutylammonium (TBA). In contrast to Kv 3.1, the relative potencies in Kv 2.1 were TBA > TEA > TPA. In Kv 3.1 and Kv 2.1, external tetrapentylammonium (TPeA) blocked K+ currents in a fast, reversible and, in contrast to TEA, time-dependent manner. The external binding of TPeA appeared to be voltage independent, unlike the effects of TPeA applied to inside-out patches. External n-alkyl-triethylammonium compounds (C8, C10 chain length) had a lower affinity than TEA in Kv 3.1, but a higher affinity than TEA in Kv 2.1. In Kv 3.1, the decrease in QA affinity was large when one or two methyl groups were substituted for ethyl groups in TEA, but minor when propyl groups replaced ethyl groups. Changes in the free energy of binding could be correlated to changes in the free energy of hydration of TEA derivatives calculated by continuum methodology. These results reveal a substantial hydrophobic component of external QA ion binding to Kv 2.1, and to a lesser degree to Kv 3.1, in addition to the generally accepted electrostatic interactions. The chain length of hydrophobic TEA derivatives affects the affinity for the hydrophobic binding site, whereas the hydropathy of QA ions determines the electrostatic interaction energy.

  6. Deterministic delivery of externally cold and precisely positioned single molecular ions

    CERN Document Server

    Leschhorn, G; Schaetz, T

    2011-01-01

    We present the preparation and deterministic delivery of a selectable number of externally cold molecular ions. A laser cooled ensemble of Mg^+ ions subsequently confined in several linear Paul traps inter-connected via a quadrupole guide serves as a cold bath for a single or up to a few hundred molecular ions. Sympathetic cooling embeds the molecular ions in the crystalline structure. MgH^+ ions, that serve as a model system for a large variety of other possible molecular ions, are cooled down close to the Doppler limit and are positioned with an accuracy of one micrometer. After the production process, severely compromising the vacuum conditions, the molecular ion is efficiently transfered into nearly background-free environment. The transfer of a molecular ion between different traps as well as the control of the molecular ions in the traps is demonstrated. Schemes, optimized for the transfer of a specific number of ions, are realized and their efficiencies are evaluated. This versatile source applicable f...

  7. Two Azimuthally Separated Regions of Cusp Ion Injection Observed via Energetic Neutral Atoms

    National Research Council Canada - National Science Library

    Abe, M; Moore, T. E; Collier, M. R; Taguchi, S

    2011-01-01

    The low-energy neutral atom (LENA) imager on the IMAGE spacecraft can detect energetic neutral atoms produced by ion injection into the cusp through a charge exchange with the Earth's hydrogen exosphere...

  8. Simulations and Theory of Ion Injection at Non-relativistic Collisionless Shocks

    Science.gov (United States)

    Caprioli, Damiano; Pop, Ana-Roxana; Spitkovsky, Anatoly

    2015-01-01

    We use kinetic hybrid simulations (kinetic ions-fluid electrons) to characterize the fraction of ions that are accelerated to non-thermal energies at non-relativistic collisionless shocks. We investigate the properties of the shock discontinuity and show that shocks propagating almost along the background magnetic field (quasi-parallel shocks) reform quasi-periodically on ion cyclotron scales. Ions that impinge on the shock when the discontinuity is the steepest are specularly reflected. This is a necessary condition for being injected, but it is not sufficient. Also, by following the trajectories of reflected ions, we calculate the minimum energy needed for injection into diffusive shock acceleration, as a function of the shock inclination. We construct a minimal model that accounts for the ion reflection from quasi-periodic shock barrier, for the fraction of injected ions, and for the ion spectrum throughout the transition from thermal to non-thermal energies. This model captures the physics relevant for ion injection at non-relativistic astrophysical shocks with arbitrary strengths and magnetic inclinations, and represents a crucial ingredient for understanding the diffusive shock acceleration of cosmic rays.

  9. Diagnostics of a charge breeder electron cyclotron resonance ion source helium plasma with the injection of ^{23}Na^{1+} ions

    Directory of Open Access Journals (Sweden)

    O. Tarvainen

    2016-05-01

    Full Text Available This work describes the utilization of an injected ^{23}Na^{1+} ion beam as a diagnostics of the helium plasma of a charge breeder electron cyclotron resonance ion source. The obtained data allows estimating the upper limit for the ion-ion collision mean-free path of the incident sodium ions, the lower limit of ion-ion collision frequencies for all charge states of the sodium ions and the lower limit of the helium plasma density. The ion-ion collision frequencies of high charge state ions are shown to be at least on the order of 1–10 MHz and the plasma density is estimated to be on the order of 10^{11}  cm^{-3} or higher. The experimental results are compared to simulations of the ^{23}Na^{1+} capture into the helium plasma. The results indicate that the lower breeding efficiency of light ions in comparison to heavier elements is probably due to different capture efficiencies in which the in-flight ionization of the incident 1+ ions plays a vital role.

  10. INJECTION OF GOLD IONS IN THE AGS BOOSTER WITH LINEAR COUPLING.

    Energy Technology Data Exchange (ETDEWEB)

    GARDNE,C.; AHRENS,L.; ROSER,T.; ZENO,K.

    1999-03-29

    Linear Coupling, introduced by skew quadrupoles, has been used for several years to enhance the multi-turn injection efficiency of gold and other heavy ions in the AGS Booster. In this paper we describe our latest measurements of the injection process and compare with models.

  11. High-current negative hydrogen ion beam production in a cesium-injected multicusp source

    Energy Technology Data Exchange (ETDEWEB)

    Takeiri, Y.; Tsumori, K.; Kaneko, O. [National Inst. for Fusion Science, Nagoya (Japan)] [and others

    1997-12-31

    A high-current negative hydrogen ion source has been developed, where 16.2 A of the H{sup -} current was obtained with a current density of 31 mA/cm{sup 2}. The ion source is a multicusp source with a magnetic filter for negative ion production, and cesium vapor is injected into the arc chamber, leading to enhancement of the negative ion yields. The cesium-injection effects are discussed, based on the experimental observations. Although the surface production of the negative ions on the cesium-covered plasma grid is thought to be a dominant mechanism of the H{sup -} current enhancement, the cesium effects in the plasma volume, such as the cesium ionization and the electron cooling, are observed, and could contribute to the improved operation of the negative ion source. (author)

  12. A look ahead: Status of the SNS external antenna ion source and the new RFQ test stand

    Science.gov (United States)

    Welton, R. F.; Aleksandrov, A.; Dudnikov, V. G.; Han, B. X.; Murray, S. N.; Pennisi, T. R.; Piller, M.; Kang, Y.; Santana, M.; Stockli, M. P.

    2015-04-01

    The U.S. Spallation Neutron Source (SNS) now operates with ˜1 MW of beam power to target with the near-term goal of delivering 1.4 MW. Plans are being considered to incorporate a second target station into the facility which will require ˜2.8 MW of beam power. Presently, H- beam pulses (˜1 ms, 60 Hz) are produced by an RF-driven, Cs-enhanced, multi-cusp ion source which injects beam into an RFQ (Radio Frequency Quadrupole) accelerator that, in turn, feeds the SNS Linac. Currently the source/RFQ system delivers ˜35 mA of pulsed current to the linac which is mostly sufficient for 1.4 MW operations while ˜50 mA are needed for the second target station upgrade. This paper provides a look forward for the SNS by providing (i) the present and future SNS source/RFQ beam requirements and our plans to achieve these, (ii) a description and status of the external antenna ion source being developed for the replacement of the current internal antenna ion source, and (iii) a description and status of the newly constructed RFQ test facility.

  13. A look ahead: Status of the SNS external antenna ion source and the new RFQ test stand

    Energy Technology Data Exchange (ETDEWEB)

    Welton, R. F., E-mail: welton@ornl.gov; Aleksandrov, A.; Han, B. X.; Murray, S. N.; Pennisi, T. R.; Piller, M.; Kang, Y.; Santana, M.; Stockli, M. P. [Spallation Neutron Source, Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN, 37830-647 (United States); Dudnikov, V. G. [Muons, Inc. 552 N. Batavia Avenue, Batavia, IL 60510 (United States)

    2015-04-08

    The U.S. Spallation Neutron Source (SNS) now operates with ∼1 MW of beam power to target with the near-term goal of delivering 1.4 MW. Plans are being considered to incorporate a second target station into the facility which will require ∼2.8 MW of beam power. Presently, H{sup −} beam pulses (∼1 ms, 60 Hz) are produced by an RF-driven, Cs-enhanced, multi-cusp ion source which injects beam into an RFQ (Radio Frequency Quadrupole) accelerator that, in turn, feeds the SNS Linac. Currently the source/RFQ system delivers ∼35 mA of pulsed current to the linac which is mostly sufficient for 1.4 MW operations while ∼50 mA are needed for the second target station upgrade. This paper provides a look forward for the SNS by providing (i) the present and future SNS source/RFQ beam requirements and our plans to achieve these, (ii) a description and status of the external antenna ion source being developed for the replacement of the current internal antenna ion source, and (iii) a description and status of the newly constructed RFQ test facility.

  14. Students' Understanding of External Representations of the Potassium Ion Channel Protein Part II: Structure-Function Relationships and Fragmented Knowledge

    Science.gov (United States)

    Harle, Marissa; Towns, Marcy H.

    2012-01-01

    Research that has focused on external representations in biochemistry has uncovered student difficulties in comprehending and interpreting external representations. This study focuses on students' understanding of three external representations (ribbon diagram, wireframe, and hydrophobic/hydrophilic) of the potassium ion channel protein. Analysis…

  15. Non-Liouvillean ion injection via resonantly enhanced two-photon ionization

    OpenAIRE

    Knyazev, B. A.

    2004-01-01

    The charge-exchange method is now one of the main techniques for ion injection into accelerators and storage rings. The disadvantages of conventional methods, based on the atom or ion stripping in a material target, are emittance growth, energy straggling, and production of ions in many charge states. Recently suggested stripping methods based on direct photoionization require employment of hard-UV lasers, which still do not exist and must obviously be very bulky and expensive. An alternative...

  16. Non-Liouvillean ion injection via resonantly enhanced two-photon ionization

    Directory of Open Access Journals (Sweden)

    B. A. Knyazev

    2004-03-01

    Full Text Available The charge-exchange method is now one of the main techniques for ion injection into accelerators and storage rings. The disadvantages of conventional methods, based on the atom or ion stripping in a material target, are emittance growth, energy straggling, and production of ions in many charge states. Recently suggested stripping methods based on direct photoionization require employment of hard-UV lasers, which still do not exist and must obviously be very bulky and expensive. An alternative method, suggested for injection of proton beams, employs excitation of the atom to 3p intermediate state with subsequent Lorentz ionization in a magnetic field gradient. This technique applies rigid requirements to laser characteristic and is not free of growing of the beam divergence. In this paper a variant of the stripping technique based on the resonantly enhanced two-photon ionization (RETPI is considered. The technique allows ionization of singly charged ions of the elements from helium to bismuth. A variant of the technique can be used for proton injection. RETPI can be applied for both ion injection and stacking, as well as for diagnostics of ion beam characteristics on the orbit. Stripping efficiency can be about 100% for the singly charged ions having the singlet ground state and decreases for the other ions. Special methods for “cleaning” unwanted atomic states in such ions, that can provide high stripping efficiency, are discussed. Excimer lasers with very moderate parameters can be employed for implementation of this technique for almost all elements. Numerical examples show that for most of the singly charged ions and for hydrogen atom necessary laser-beam energy density is merely 0.5–8  J/cm^{2} for a 1 m interaction region, and is 10 times higher for several light ions.

  17. Non-Liouvillean ion injection via resonantly enhanced two-photon ionization

    Science.gov (United States)

    Knyazev, B. A.

    2004-03-01

    The charge-exchange method is now one of the main techniques for ion injection into accelerators and storage rings. The disadvantages of conventional methods, based on the atom or ion stripping in a material target, are emittance growth, energy straggling, and production of ions in many charge states. Recently suggested stripping methods based on direct photoionization require employment of hard-UV lasers, which still do not exist and must obviously be very bulky and expensive. An alternative method, suggested for injection of proton beams, employs excitation of the atom to 3p intermediate state with subsequent Lorentz ionization in a magnetic field gradient. This technique applies rigid requirements to laser characteristic and is not free of growing of the beam divergence. In this paper a variant of the stripping technique based on the resonantly enhanced two-photon ionization (RETPI) is considered. The technique allows ionization of singly charged ions of the elements from helium to bismuth. A variant of the technique can be used for proton injection. RETPI can be applied for both ion injection and stacking, as well as for diagnostics of ion beam characteristics on the orbit. Stripping efficiency can be about 100% for the singly charged ions having the singlet ground state and decreases for the other ions. Special methods for “cleaning” unwanted atomic states in such ions, that can provide high stripping efficiency, are discussed. Excimer lasers with very moderate parameters can be employed for implementation of this technique for almost all elements. Numerical examples show that for most of the singly charged ions and for hydrogen atom necessary laser-beam energy density is merely 0.5 8 J/cm2 for a 1m interaction region, and is 10times higher for several light ions.

  18. Computer simulations for rf design of a Spallation Neutron Source external antenna H ion source

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Sung-Woo [ORNL; Goulding, Richard Howell [ORNL; Kang, Yoon W [ORNL; Shin, Ki [ORNL; Welton, Robert F [ORNL

    2010-01-01

    Electromagnetic modeling of the multicusp external antenna H ion source for the Spallation Neutron Source SNS has been performed in order to optimize high-power performance. During development of the SNS external antenna ion source, antenna failures due to high voltage and multicusp magnet holder rf heating concerns under stressful operating conditions led to rf characteristics analysis. In rf simulations, the plasma was modeled as an equivalent lossy metal by defining conductivity as . Insulation designs along with material selections such as ferrite and Teflon could be included in the computer simulations to compare antenna gap potentials, surface power dissipations, and input impedance at the operating frequencies, 2 and 13.56 MHz. Further modeling and design improvements are outlined in the conclusion.

  19. Properties of Laser-Produced Highly Charged Heavy Ions for Direct Injection Scheme

    CERN Document Server

    Sakakibara, Kazuhiko; Hayashizaki, Noriyosu; Ito, Taku; Kashiwagi, Hirotsugu; Okamura, Masahiro

    2005-01-01

    To accelerate highly charged intense ion beam, we have developed the Direct Plasma Injection Scheme (DPIS) with laser ion source. In this scheme an ion beam from a laser ion source is injected directly to a RFQ linac without a low energy beam transport (LEBT) and the beam loss in the LEBT can be avoided. We achieved high current acceleration of carbon ions (60mA) by DPIS with the high current optimized RFQ. As the next setp we will use heavier elements like Ag, Pb, Al and Cu as target in LIS (using CO2, Nd-YAG or other laser) for DPIS and will examine properties of laser-produced plasma (the relationship of between charge state and laser power density, the current dependence of the distance from the target, etc).

  20. ION INJECTION AT QUASI-PARALLEL SHOCKS SEEN BY THE CLUSTER SPACECRAFT

    Energy Technology Data Exchange (ETDEWEB)

    Johlander, A.; Vaivads, A.; Khotyaintsev, Yu. V. [Swedish Institute of Space Physics, Uppsala (Sweden); Retinò, A. [Laboratoire de Physique des Plasmas, CNRS/Ecole Polytechnique/UPMC, Palaiseau (France); Dandouras, I., E-mail: andreas.johlander@irfu.se [Université Paul Sabatier Toulouse III, Toulouse (France)

    2016-01-20

    Collisionless shocks in space plasma are known to be capable of accelerating ions to very high energies through diffusive shock acceleration (DSA). This process requires an injection of suprathermal ions, but the mechanisms producing such a suprathermal ion seed population are still not fully understood. We study acceleration of solar wind ions resulting from reflection off short large-amplitude magnetic structures (SLAMSs) in the quasi-parallel bow shock of Earth using in situ data from the four Cluster spacecraft. Nearly specularly reflected solar wind ions are observed just upstream of a SLAMS. The reflected ions are undergoing shock drift acceleration (SDA) and obtain energies higher than the solar wind energy upstream of the SLAMS. Our test particle simulations show that solar wind ions with lower energy are more likely to be reflected off the SLAMS, while high-energy ions pass through the SLAMS, which is consistent with the observations. The process of SDA at SLAMSs can provide an effective way of accelerating solar wind ions to suprathermal energies. Therefore, this could be a mechanism of ion injection into DSA in astrophysical plasmas.

  1. Ion injection at Quasi-parallel Shocks Seen by the Cluster Spacecraft

    Science.gov (United States)

    Johlander, A.; Vaivads, A.; Khotyaintsev, Yu. V.; Retinò, A.; Dandouras, I.

    2016-01-01

    Collisionless shocks in space plasma are known to be capable of accelerating ions to very high energies through diffusive shock acceleration (DSA). This process requires an injection of suprathermal ions, but the mechanisms producing such a suprathermal ion seed population are still not fully understood. We study acceleration of solar wind ions resulting from reflection off short large-amplitude magnetic structures (SLAMSs) in the quasi-parallel bow shock of Earth using in situ data from the four Cluster spacecraft. Nearly specularly reflected solar wind ions are observed just upstream of a SLAMS. The reflected ions are undergoing shock drift acceleration (SDA) and obtain energies higher than the solar wind energy upstream of the SLAMS. Our test particle simulations show that solar wind ions with lower energy are more likely to be reflected off the SLAMS, while high-energy ions pass through the SLAMS, which is consistent with the observations. The process of SDA at SLAMSs can provide an effective way of accelerating solar wind ions to suprathermal energies. Therefore, this could be a mechanism of ion injection into DSA in astrophysical plasmas.

  2. Fixation of external drainage device with injectable shape-memory alloy clips.

    Science.gov (United States)

    Olson, Jeffrey L; Erlanger, Michael

    2013-09-01

    To describe a novel surgical technique and novel surgical instrumentation for fixating an extraocular drainage device used for glaucoma-filtering surgery. The technique was performed in a laboratory setting using ex-vivo porcine eyes. We describe the surgical technique of using injectable, 25-gauge shape-memory clip system to fixate an Ahmed drainage device. The use of an injectable, shape-memory alloy clip provides the advantages of rapid, easy deployment and decreased risk of late suture failure. Importantly, the injectable, shape-memory clips can be used in surgical situations where suturing is difficult and time intensive, such as those encountered during glaucoma drainage device placement. The use of an injectable, shape-memory alloy clip is a promising new surgical tool and technique for fixating an extraocular drainage device used for glaucoma surgery.

  3. Source Determination for Substorm-Related Ion Injections

    Science.gov (United States)

    Strangeway, Robert J.; Evans, David (Technical Monitor)

    2001-01-01

    The grant supported an effort to restore and analyze data from the Spacecraft Charging at High Altitude (SCATHA) spacecraft. This spacecraft, which was originally an Air Force mission, was launched into a near geo-synchronous orbit in early 1979 to, investigate the inner magnetosphere at altitudes where it was known that spacecraft can undergo significant charging events. SCATHA included an ion composition experiment (designated SC8) and in many ways was a precursor to other missions, such as the AMPTE Charge Composition Explorer.

  4. Externally Controlled Injection of Electrons by a Laser Pulse in a Laser Wakefield Electron Accelerator

    CERN Document Server

    Chen Szu Yuan; Chen Wei Ting; Chien, Ting-Yei; Lee, Chau-Hwang; Lin, Jiunn-Yuan; Wang, Jyhpyng

    2005-01-01

    Spatially and temporally localized injection of electrons is a key element for development of plasma-wave electron accelerator. Here we report the demonstration of two different schemes for electron injection in a self-modulated laser wakefield accelerator (SM-LWFA) by using a laser pulse. In the first scheme, by implementing a copropagating laser prepulse with proper timing, we are able to control the growth of Raman forward scattering and the production of accelerated electrons. We found that the stimulated Raman backward scattering of the prepulse plays the essential role of injecting hot electrons into the fast plasma wave driven by the pump pulse. In the second scheme, by using a transient density ramp we achieve self-injection of electrons in a SM-LWFA with spatial localization. The transient density ramp is produced by a prepulse propagating transversely to drill a density depression channel via ionization and expansion. The same mechanism of injection with comparable efficiency is also demonstrated wi...

  5. Tunable single and dual mode operation of an external cavity quantum-dot injection laser

    Energy Technology Data Exchange (ETDEWEB)

    Biebersdorf, A [Photonics and Optoelectronics Group, Physics Department and CeNS, Ludwig-Maximilians-Universitaet, Amalienstrasse 54, D-80799 Munich (Germany); Lingk, C [Photonics and Optoelectronics Group, Physics Department and CeNS, Ludwig-Maximilians-Universitaet, Amalienstrasse 54, D-80799 Munich (Germany); De Giorgi, M [Photonics and Optoelectronics Group, Physics Department and CeNS, Ludwig-Maximilians-Universitaet, Amalienstrasse 54, D-80799 Munich (Germany); Feldmann, J [Photonics and Optoelectronics Group, Physics Department and CeNS, Ludwig-Maximilians-Universitaet, Amalienstrasse 54, D-80799 Munich (Germany); Sacher, J [Sacher Lasertechnik GmbH, Hannah Arendt Strasse 3-7, D-35037 Marburg (Germany); Arzberger, M [Walter Schottky Institut, Technische Universitaet Muenchen, Am Coulombwall, D-85748 Garching (Germany); Ulbrich, C [Walter Schottky Institut, Technische Universitaet Muenchen, Am Coulombwall, D-85748 Garching (Germany); Boehm, G [Walter Schottky Institut, Technische Universitaet Muenchen, Am Coulombwall, D-85748 Garching (Germany); Amann, M-C [Walter Schottky Institut, Technische Universitaet Muenchen, Am Coulombwall, D-85748 Garching (Germany); Abstreiter, G [Walter Schottky Institut, Technische Universitaet Muenchen, Am Coulombwall, D-85748 Garching (Germany)

    2003-08-21

    We investigate quantum-dot (QD) lasers in an external cavity using Littrow and Littman configurations. Here, we report on a continuously tunable QD laser with a broad tuning range from 1047 to 1130 nm with high stability and efficient side mode suppression. The full-width at half-maximum of the laser line is 0.85 nm determined mainly by the quality of the external grating. This laser can be operated in a dual-mode modus, where the mode-spacing can be tuned continuously between 1.1 and 34 nm. Simultaneous emission of the two laser modes is shown by sum frequency generation experiments.

  6. Effects of external magnetic field on oblique propagation of ion acoustic cnoidal wave in nonextensive plasma

    Science.gov (United States)

    Farhad Kiyaei, Forough; Dorranian, Davoud

    2017-01-01

    Effects of the obliqueness and the strength of external magnetic field on the ion acoustic (IA) cnoidal wave in a nonextensive plasma are investigated. The reductive perturbation method is employed to derive the corresponding KdV equation for the IA wave. Sagdeev potential is extracted, and the condition of generation of IA waves in the form of cnoidal waves or solitons is discussed in detail. In this work, the domain of allowable values of nonextensivity parameter q for generation of the IA cnoidal wave in the plasma medium is considered. The results show that only the compressive IA wave may generate and propagate in the plasma medium. Increasing the strength of external magnetic field will increase the frequency of the wave and decrease its amplitude, while increasing the angle of propagation will decrease the frequency of the wave and increase its amplitude.

  7. Simultaneous ion luminescence imaging and spectroscopy of individual aerosol particles with external proton or helium microbeams

    Energy Technology Data Exchange (ETDEWEB)

    Kada, Wataru, E-mail: kada.wataru@gunma-u.ac.jp [Gunma University, 1-5-1 Tenjin-cho, Kiryu, Gunma 376-8515 (Japan); Satoh, Takahiro; Yokoyama, Akihito; Koka, Masashi; Kamiya, Tomihiro [Takasaki Advanced Radiation Research Institute, Japan Atomic Energy Agency, 1233 Watanuki-machi, Takasaki, Gunma 370-1292 (Japan)

    2014-08-01

    Simultaneous microscopic imaging and spectroscopy of individual aerosol particles were performed with an external microbeam. Visible luminescence induced by the external microbeam was successfully used as a probe to detect organic contaminants in the targets. Combined ion luminescence (IL)/particle-induced X-ray emission (PIXE) analysis of the aerosol targets revealed microscopic chemical and elemental composition distributions under ambient atmospheric conditions. The simple confocal micro-optics for the IL spectroscopy and microscopic imaging were sufficiently sensitive for detecting these molecules at sub-parts per million concentrations and at a wavelength resolution of less than 5 nm. The IL spectra were monitored to prevent severe damage to the samples. Furthermore, our IL system has the advantage that it is simple to add to a conventional micro-PIXE system.

  8. A novel approach for generating flat optical frequency comb based on externally injected gain-switching distributed feedback semiconductor laser

    Science.gov (United States)

    Zhu, Huatao; Wang, Rong; Pu, Tao; Xiang, Peng; Zheng, Jilin; Fang, Tao

    2017-02-01

    In this paper, a novel approach for generating flat optical frequency comb (OFC) based on externally injected gain-switched distributed feedback (DFB) semiconductor laser is proposed and experimentally demonstrated. In the proposed system, the flatness, the number of OFC spectral lines, and the spectral line to background noise ratio can be tuned to their optimized values by adjusting the current of the modulation signal, the injection ratio and the detuning frequency. Since the frequency of the modulation signal decides the frequency spacing of the output spectral lines, OFC spectral lines of different spacing can be achieved. In the experiment, 10 spectral lines with 1.5 dB power variation are demonstrated to verify the proposed approach. In addition, the expansion of the spectral line is investigated.

  9. Ion transport studies on the PLT tokamak during neutral beam injection

    Energy Technology Data Exchange (ETDEWEB)

    Suckewer, S.; Cavallo, A.; Cohen, S.; Daughney, C.; Denne, B.; Hinnov, E.; Hosea, J.; Hulse, R.; Hwang, D.; Schilling, G.

    1983-12-01

    Radial transport of ions during co- and counter-neutral beam heating in the PLT tokamak has been studied, using molybdenum and scandium ions as tracer elements. The time evolution of the radial profiles of several ionization stages of both elements, injected by laser blowoff during the neutral beam heating, were measured under three significantly different beam-plasma combinations. No noticeable differences in the radial profiles attributable to the beam direction were observed. However, a given injected amount resulted in considerably larger interior concentrations of the tracer element in the counter-beam heating cases, suggesting larger penetration of the plasma periphery. Computer simulation with the MIST code suggests a net inward drift of the order 10/sup 3/ cm/sec superposed to a diffusion coefficient of the order 10/sup 4/ cm/sup 2//sec for both scandium and molybdenum ions. Injection of larger amounts of the tracer element, sufficient to cause measurable central electron temperature changes, resulted in dramatic changes in ion-state distributions, making some appear peaked in the center while others disappeared. This effect could be produced with both co- and counter-beam heating, but with lesser amounts in the latter case. It is interpreted as rearrangement of the ionization balance, rather than any preferential accumulation of the injected element.

  10. Mass transport model of ions within biofilms under the effect of external field

    Institute of Scientific and Technical Information of China (English)

    WANG Jun; TANG Xue-xi

    2006-01-01

    A mass transport model was developed to predict the transport rate of ions within biofilms, which was experimentally verified using the fluxes ofNH4+ and Ca2+ through the heterotrophic biofilms with the thickness varying from 230 to 1430 μm under the effect of external field in the range of-20 V/m to 60 V/m. It is found that the result predicted by the model is in agreement with the experimentally obtained one, with the error less than 5 percent for the thin biofilms. The error increases with the increase of the biofilm thickness. The transport rate of ions caused by electric migration is affected by the charges, field strength, and biofilm thickness and so on.

  11. Multi-turn injection into a heavy-ion synchrotron in the presence of space charge

    CERN Document Server

    Appel, Sabrina

    2014-01-01

    For heavy-ion synchrotrons an efficient Multi-Turn Injection (MTI) from the injector linac is crucial in order to reach the specified currents using the available machine acceptance. The beam loss during the MTI must not exceed the limits determined by machine protection and by the vacuum requirements. Especially for low energy and intermediate charge state ions, the beam loss at the injection septum can cause a degradation of the vacuum and a corresponding reduction of the beam lifetime. In order to optimize the injection of intense beams a very detailed simulation model was developed. Besides the closed orbit bump, lattice errors, the position of the septum and other aperture limiting components the transverse space charge force is included self-consistently. The space charge force causes a characteristic shift of the optimum tunes and a smoothing of the phase space density.

  12. Chaotic behavior of collective ion dynamics in the presence of an external static magnetic field

    Science.gov (United States)

    Poria, Swarup; Ghosh, Samiran

    2016-06-01

    The two-dimensional nonlinear collective ion dynamics in the presence of external magnetic field in an electron-ion plasma is investigated. The analysis is performed for traveling plane waves to elucidate the various aspects of the phase-space dynamics. The presence of magnetic field makes the dynamics of the nonlinear wave complex with a complicated phase-space behavior. Thus, the nonlinear wave supports a wide class of nonlinear structures viz., single soliton, multi-soliton, periodic, and quasi-periodic oscillations depending on the values of M (Mach number) and Ω (the ratio of ion gyro-frequency to the ion plasma frequency). The computational results predict the chaotic behavior of the nonlinear wave and the transition to chaos takes place when Ω ≳ 0.35 depending on the direction of propagation and the value of M. The amplitude of the wave depends on the obliqueness of the propagation and Mach number, whereas the magnetic field changes the dispersion properties of the wave.

  13. Phase space linearization and external injection of electron bunches into laser-driven plasma wakefields at REGAE

    Energy Technology Data Exchange (ETDEWEB)

    Zeitler, Benno Michael Georg [Hamburg Univ. (Germany). Fakultaet fuer Mathematik, Informatik und Naturwissenschaften

    2017-01-15

    Laser Wake field Acceleration (LWFA) has the potential to become the next-generation acceleration technique for electrons. In particular, the large field gradients provided by these plasma-based accelerators are an appealing property, promising a significant reduction of size for future machines and user facilities. Despite the unique advantages of these sources, however, as of today, the produced electron bunches cannot yet compete in all beam quality criteria compared to conventional acceleration methods. Especially the stability in terms of beam pointing and energy gain, as well as a comparatively large energy spread of LWFA electron bunches require further advancement for their applicability. The accelerated particles are typically trapped from within the plasma which is used to create the large field gradients in the wake of a high-power laser. From this results a lack of control and access to observing the actual electron injection - and, consequently, a lack of experimental verification. To tackle this problem, the injection of external electrons into a plasma wakefield seems promising. In this case, the initial beam parameters are known, so that a back-calculation and reconstruction of the wakefield structure are feasible. Such an experiment is planned at the Relativistic Electron Gun for Atomic Exploration (REGAE). REGAE, which is located at DESY in Hamburg, is a small linear accelerator offering unique beam parameters compatible with the requirements of the planned experiment. The observations and results gained from such an external injection are expected to improve the beam quality and stability of internal injection variants, due to the broadened understanding of the underlying plasma dynamics. Furthermore, an external injection will always be required for so-called staging of multiple LWFA-driven cavities. Also, the demonstration of a suchlike merging of conventional and plasma accelerators gives rise to novel hybrid accelerators, where the matured

  14. Preferential heating of light ions during an ionospheric Ar(+) injection experiment

    Science.gov (United States)

    Pollock, C. J.; Chandler, M. O.; Moore, T. E.; Arnoldy, R. L.; Kintner, P. M.; Chesney, S.; Cahill, L. J., Jr.

    1995-01-01

    The Argon Release for Controlled Studies (ARCS) 4 sounding rocket was launched northward into high altitude from Poker Flat Research Range on February 23, 1990. The vehicle crossed geomagnetic field lines containing discrete auroral activity. An instrumented subpayload released 100-eV and 200-eV Ar(+) ion beams sequentially, in a direction largely perpendicular to both the local geomagnetic field and the subpayload spin axis. The instrumented main payload was separated along field lines from the beam emitting subpayload by a distance which increased at a steady rate of approximately 2.4 m/s. Three dimensional mass spectrometric ion observations of ambient H(+) and O(+) ions, obtained on board the main payload, are presented. Main payload electric field observations in the frequency range 0-16 kHz, are also presented. These observations are presented to demonstrate the operation of transverse ion acceleration, which was differential with respect to ion mass, primarily during 100-eV beam operations. The preferential transverse acceleration of ambient H(+) ions, as compared with ambient O(+) ions, during the second, third, fourth, and fifth 100-eV beam operations, is attributed to a resonance among the injected Ar(+) ions, beam-generated lower hybrid waves, and H(+) ions in the tail of the ambient thermal distribution. This work provides experimental support of processes predicted by previously published theory and simulations.

  15. Design and Experimental Study of the External H~- Ion Source for a 10 MeV Medical Cyclotron

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    A 10 MeV medical cyclotron has been designed by the BRIF Division at CIAE, for which the H- beam is axially injected to the machine. To satisfy the requirement for the cyclotron with H- ion source, a compact multicusp H- ion source has

  16. The design of high power, external antennas for radio frequency multicusp ion sources

    Science.gov (United States)

    Welton, R. F.; Stockli, M. P.; Roseberry, R. T.; Kang, Y.; Keller, R.

    2004-05-01

    The ion source for the Spallation Neutron Source (SNS) is a radio-frequency, multicusp source designed to deliver H- beam pulses of 45 mA to the SNS accelerator, with a pulse length of 1 ms and a repetition rate of 60 Hz. In order to achieve this performance the source must operate with both high peak rf power, ˜45 kW, and high average rf power, ˜3 kW, over an operational run period of 3 weeks. The most critical source component in this respect is the plasma-immersed, porcelain coated rf antenna which can be susceptible to damage during high power operation. The DESY group has developed an external antenna configuration utilizing an Al2O3 plasma chamber which has demonstrated a very long operational period exceeding 25 000 h. Their source operates with peak rf powers comparable to the SNS source but with greatly reduced average rf powers, ˜50 W. In order to explore the applicability of this external antenna concept to high average power ion sources like the SNS source, we have performed thermal, mechanical, and electromagnetic analyses of the Al2O3 plasma chamber. This article discusses the final design which has resulted from these studies as well as estimates of the power limitations of such devices.

  17. The status of the SNS external antenna ion source and spare RFQ test facility

    Energy Technology Data Exchange (ETDEWEB)

    Welton, R. F., E-mail: welton@ornl.gov; Aleksandrov, A. V.; Han, B. X.; Kang, Y.; Murray, S. N.; Pennisi, T. R.; Piller, C.; Santana, M.; Stockli, M. P. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, Tennessee 37830-6471 (United States); Dudnikov, V. G. [Muons, Inc., 552 N. Batavia Avenue, Batavia, Illinois 60510 (United States)

    2016-02-15

    The Oak Ridge National Laboratory operates the Spallation Neutron Source, consisting of a H{sup −} ion source, a 1 GeV linac and an accumulator ring. The accumulated <1 μs-long, ∼35 A beam pulses are extracted from the ring at 60 Hz and directed onto a liquid Hg target. Spalled neutrons are directed to ∼20 world class instruments. Currently, the facility operates routinely with ∼1.2 MW of average beam power, which soon will be raised to 1.4 MW. A future upgrade with a second target station calls for raising the power to 2.8 MW. This paper describes the status of two accelerator components expected to play important roles in achieving these goals: a recently acquired RFQ accelerator and the external antenna ion source. Currently, the RFQ is being conditioned in a newly constructed 2.5 MeV Integrated Test Facility (ITF) and the external antenna source is also being tested on a separate test stand. This paper presents the results of experiments and the testing of these systems.

  18. ION ACCELERATION AT THE QUASI-PARALLEL BOW SHOCK: DECODING THE SIGNATURE OF INJECTION

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, Torbjörn; Haynes, Christopher T.; Burgess, D. [School of Physics and Astronomy, Queen Mary University of London, London, E1 4NS (United Kingdom); Mazelle, Christian X. [IRAP, Université Paul Sabatier Toulouse III-CNRS, 31028 Toulouse Cedex 4 (France)

    2016-03-20

    Collisionless shocks are efficient particle accelerators. At Earth, ions with energies exceeding 100 keV are seen upstream of the bow shock when the magnetic geometry is quasi-parallel, and large-scale supernova remnant shocks can accelerate ions into cosmic-ray energies. This energization is attributed to diffusive shock acceleration; however, for this process to become active, the ions must first be sufficiently energized. How and where this initial acceleration takes place has been one of the key unresolved issues in shock acceleration theory. Using Cluster spacecraft observations, we study the signatures of ion reflection events in the turbulent transition layer upstream of the terrestrial bow shock, and with the support of a hybrid simulation of the shock, we show that these reflection signatures are characteristic of the first step in the ion injection process. These reflection events develop in particular in the region where the trailing edge of large-amplitude upstream waves intercept the local shock ramp and the upstream magnetic field changes from quasi-perpendicular to quasi-parallel. The dispersed ion velocity signature observed can be attributed to a rapid succession of ion reflections at this wave boundary. After the ions’ initial interaction with the shock, they flow upstream along the quasi-parallel magnetic field. Each subsequent wavefront in the upstream region will sweep the ions back toward the shock, where they gain energy with each transition between the upstream and the shock wave frames. Within three to five gyroperiods, some ions have gained enough parallel velocity to escape upstream, thus completing the injection process.

  19. Design and development of a helium injection system to improve external leakage detection during liquid nitrogen immersion tests

    Science.gov (United States)

    Townsend, Andrew; Mishra, Rakesh

    2016-10-01

    The testing of assemblies for use in cryogenic systems commonly includes evaluation at or near operating (therefore cryogenic) temperature. Typical assemblies include valves and pumps for use in liquid oxygen-liquid hydrogen rocket engines. One frequently specified method of cryogenic external leakage testing requires the assembly, pressurized with gaseous helium (GHe), be immersed in a bath of liquid nitrogen (LN2) and allowed to thermally stabilize. Component interfaces are then visually inspected for leakage (bubbles). Unfortunately the liquid nitrogen will be boiling under normal, bench-top, test conditions. This boiling tends to mask even significant leakage. One little known and perhaps under-utilized property of helium is the seemingly counter-intuitive thermodynamic property that when ambient temperature helium is bubbled through boiling LN2 at a temperature of -195.8 °C, the temperature of the liquid nitrogen will reduce. This paper reports on the design and testing of a novel proof-of-concept helium injection control system confirming that it is possible to reduce the temperature of an LN2 bath below boiling point through the controlled injection of ambient temperature gaseous helium and then to efficiently maintain a reduced helium flow rate to maintain a stabilized liquid temperature, enabling clear visual observation of components immersed within the LN2. Helium saturation testing is performed and injection system sizing is discussed.

  20. Controlling domain wall nucleation and injection through focussed ion beam irradiation in perpendicularly magnetized nanowires

    Science.gov (United States)

    Beguivin, A.; Petit, D. C. M. C.; Mansell, R.; Cowburn, R. P.

    2017-01-01

    Using Ga+ focussed ion beam irradiation of Ta/Pt/CoFeB/Pt perpendicularly magnetized nanowires, the nucleation and injection fields of domain walls into the nanowires is controlled. The nucleation and injection fields can be varied as a function of dose, however, the range of injection fields is found to be limited by the creation of a step in anisotropy between the irradiated and unirradiated regions. This can be altered by defocussing the beam, which allows the injection fields to be further reduced. The ability to define an arbitrary dose profile allows domain walls to be injected at different fields either side of an asymmetrically irradiated area, which could form the initial stage of a logic device. The effect of the thickness of the magnetic layer and the thickness of a Ta underlayer on the dose required to remove the perpendicular anisotropy is also studied and is seen that for similar Ta underlayers the dose is determined by the thickness of the magnetic layer rather than its anisotropy. This finding is supported by some transport of ions in matter simulations.

  1. Phase space generation for proton and carbon ion beams for external users’ applications at the Heidelberg Ion Therapy Center

    Directory of Open Access Journals (Sweden)

    Thomas eTessonnier

    2016-01-01

    Full Text Available In the field of radiation therapy, accurate and robust dose calculation is required. For this purpose, precise modeling of the irradiation system and reliable computational platforms are needed. At the Heidelberg Ion Therapy Center (HIT, the beamline has been already modeled in the FLUKA Monte Carlo code. However, this model was kept confidential for disclosure reasons and was not available for any external team. The main goal of this study was to create efficiently phase space (PS files for proton and carbon ion beams, for all energies and foci available at HIT. PS are representing the characteristics of each particle recorded (charge, mass, energy, coordinates, direction cosines, generation at a certain position along the beam path. In order to achieve this goal, keeping a reasonable data size but maintaining the requested accuracy for the calculation, we developed a new approach of beam PS generation with the Monte-Carlo code FLUKA. The generated PS were obtained using an infinitely narrow beam and recording the desired quantities after the last element of the beamline, with a discrimination of primaries or secondaries. In this way, a unique PS can be used for each energy to accommodate the different foci by combining the narrow-beam scenario with a random sampling of its theoretical Gaussian beam in vacuum. PS can also reproduce the different patterns from the delivery system, when properly combined with the beam scanning information. MC simulations using PS have been compared to simulations including the full beamline geometry and have been found in very good agreement for several cases (depth dose distributions, lateral dose profiles, with relative dose differences below 0.5%. This approach has also been compared with measured data of ion beams with different energies and foci, resulting in a very satisfactory agreement. Hence, the proposed approach was able to fulfill the different requirements and has demonstrated its capability for

  2. Injectable silver nanosensors: in vivo dosimetry for external beam radiotherapy using positron emission tomography

    DEFF Research Database (Denmark)

    Christensen, Anders Nymark; Rydhög, J. S.; Søndergaard, Rikke Vicki;

    2016-01-01

    Development of safe and efficient radiotherapy routines requires quantification of the delivered absorbed dose to the cancer tissue in individual patients. In vivo dosimetry can provide accurate information about the absorbed dose delivered during treatment. In the current study, a novel silver......-nanosensor formulation based on poly(vinylpyrrolidinone)-coated silver nanoparticles formulated in a gelation matrix composed of sucrose acetate isobutyrate has been developed for use as an in vivo dosimeter for external beam radiotherapy. In situ photonuclear reactions trigger the formation of radioactive (106)Ag......, which enables post treatment verification of the delivered dose using positron emission tomography imaging. The silver-nanosensor was investigated in a tissue equivalent thorax phantom using clinical settings and workflow for both standard fractionated radiotherapy (2 Gy) and stereotactic radiotherapy...

  3. Study On The External Gas-Assisted Mold Temperature Control For Thin Wall Injection Molding

    Directory of Open Access Journals (Sweden)

    ThanhTrung Do

    2017-03-01

    Full Text Available Dynamic mold surface temperature control (DMTC has many advantages in micro-injection molding as well as thin-wall molding product. In this paper, DMTC will be applied for the thin-wall molding part with the observation of the weldline appearance and the weldline strength. The heating step of DMTC will be achieved by the hot air flow directly to the weldline area. The results show that the heating rate could be reached to 4.5C/s, which could raising the mold surface from 30C to over 120C within 15 s. The melt filling was operated with high temperature at the weldline area; therefore, the weldline appearance was eliminated. In addition, the weldline strength was also improved. The results show that the thinner part had the higher strength of the weldline

  4. Solid state generator for powerful radio frequency ion sources in neutral beam injection systems

    Energy Technology Data Exchange (ETDEWEB)

    Kraus, W.; Fantz, U.; Heinemann, B.; Franzen, P.

    2015-02-15

    Radio frequency ion sources used in neutral beam injection systems (NBI) of fusion machines are currently supplied by self-excited RF generators. These generators have both a low power efficiency and a limited frequency stability, therefore transistorized amplifiers are being considered for the power supply of the next generation of RF sources. A 75 kW generator, originally designed for broadcasting, has been tested with a negative ion source. High operational reliability and a very good matching to the plasma load has been demonstrated. These results make this generator type a very promising candidate for future NBI systems.

  5. Effect of the total RF voltage on heavy ions at injection energy in the LHC

    CERN Document Server

    Schaumann, Michaela; Jebramcik, Marc Andre; Jowett, John; Mertens, Tom; CERN. Geneva. ATS Department

    2017-01-01

    Emittance growth and particle losses from intra-beam scattering (IBS) are an important source of beam losses, especially at injection energy, for the heavy ions in LHC. The IBS diffusion rates are, among other factors, roughly inversely proportional to the bunch length and energy spread. Since the total RF voltage affects these parameters, it can be optimized to reduce the emittance growth and particle losses introduced by the aforementioned mechanism. During the 2016 proton-lead run, observations of the lifetime of lead-ion beams at injection energy, and at different RF voltages, were made during a dedicated fill. This note summaries these observations and compares the beam evolution with tracking simulations using the Collider Time Evolution (CTE) program.

  6. Effect of dust ion collision on dust ion acoustic waves in the framework of damped Zakharov-Kuznetsov equation in presence of external periodic force

    Science.gov (United States)

    Kanti Das, Tushar; Ali, Rustam; Chatterjee, Prasanta

    2017-10-01

    The dynamics of dust ion acoustic waves (DIAWs) is investigated in a magnetized dusty plasma whose constituents are cold ions, superthermal electrons, and dust particles in the framework of a damped Zakharov-Kuznetsov (dZK) equation in the presence of externally applied periodic force. The dZK equation is derived employing the standard reductive perturbation technique. The effect of dust ion collision on the quasiperiodic and chaotic motion of dust ion acoustic waves is discussed. It is observed that the collision frequency νid 0 plays the role of a switching parameter from the quasiperiodic route to chaos for the DIAWs.

  7. Two Azimuthally Separated Regions of Cusp Ion Injection Observed via Energetic Neutral Atoms

    Science.gov (United States)

    Abe, M.; Taguchi, S.; Collier, M. R.; Moore, T. E.

    2011-01-01

    The low-energy neutral atom (LENA) imager on the IMAGE spacecraft can detect energetic neutral atoms produced by ion injection into the cusp through a charge exchange with the Earth's hydrogen exosphere. We examined the occurrence of the LENA cusp signal during positive IMF B(sub z) in terms of the arrival direction and the IMF clock angle theta(sub CA). Results of statistical analyses show that the occurrence frequency is high on the postnoon side when theta(sub CA) is between approximately 20 degrees and approximately 50 degrees. This is ascribed to ion injection caused by cusp reconnection typical of positive IMF B(sub z). Our results also show that there is another situation of high occurrence frequency, which can be identified with theta(sub CA) of approximately 30 degrees to approximately 80 degrees. When theta(sub CA) is relatively large (60 degrees - 80 degrees), occurrence frequencies are high at relatively low latitudes over a wide extent spanning both prenoon and postnoon sectors. This feature suggests that the ion injection is caused by reconnection at the dayside magnetopause. Its postnoon side boundary shifts toward the prenoon as theta(sub CA) decreases. When theta(sub CA) is less than approximately 50 degrees, the high occurrence frequency exists well inside the prenoon sector, which is azimuthally separated from the postnoon region ascribed to cusp reconnection. The prenoon region, which is thought due to ion injection caused by dayside reconnection, may explain the recent report that proton aurora brightening occurs in the unanticipated prenoon sector of the northern high-latitude ionosphere for IMF B(sub y) greater than 0 and B(sub z) greater than 0.

  8. Injectable silver nanosensors: in vivo dosimetry for external beam radiotherapy using positron emission tomography

    Science.gov (United States)

    Christensen, A. N.; Rydhög, J. S.; Søndergaard, R. V.; Andresen, T. L.; Holm, S.; Munck Af Rosenschöld, P.; Conradsen, K.; Jølck, R. I.

    2016-05-01

    Development of safe and efficient radiotherapy routines requires quantification of the delivered absorbed dose to the cancer tissue in individual patients. In vivo dosimetry can provide accurate information about the absorbed dose delivered during treatment. In the current study, a novel silver-nanosensor formulation based on poly(vinylpyrrolidinone)-coated silver nanoparticles formulated in a gelation matrix composed of sucrose acetate isobutyrate has been developed for use as an in vivo dosimeter for external beam radiotherapy. In situ photonuclear reactions trigger the formation of radioactive 106Ag, which enables post treatment verification of the delivered dose using positron emission tomography imaging. The silver-nanosensor was investigated in a tissue equivalent thorax phantom using clinical settings and workflow for both standard fractionated radiotherapy (2 Gy) and stereotactic radiotherapy (10- and 22 Gy) in a high-energy beam setting (18 MV). The developed silver-nanosensor provided high radiopacity on the planning CT-scans sufficient for patient positioning in image-guided radiotherapy and provided dosimetric information about the absorbed dose with a 10% and 8% standard deviation for the stereotactic regimens, 10 and 22 Gy, respectively.Development of safe and efficient radiotherapy routines requires quantification of the delivered absorbed dose to the cancer tissue in individual patients. In vivo dosimetry can provide accurate information about the absorbed dose delivered during treatment. In the current study, a novel silver-nanosensor formulation based on poly(vinylpyrrolidinone)-coated silver nanoparticles formulated in a gelation matrix composed of sucrose acetate isobutyrate has been developed for use as an in vivo dosimeter for external beam radiotherapy. In situ photonuclear reactions trigger the formation of radioactive 106Ag, which enables post treatment verification of the delivered dose using positron emission tomography imaging. The

  9. Rare-earth neutral metal injection into an electron beam ion trap plasma

    Energy Technology Data Exchange (ETDEWEB)

    Magee, E. W., E-mail: magee1@llnl.gov; Beiersdorfer, P.; Brown, G. V. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Hell, N. [Lawrence Livermore National Laboratory, Livermore, California 94550 (United States); Dr. Remeis-Sternwarte and ECAP, Universität Erlangen-Nürnberg, 96049 Bamberg (Germany)

    2014-11-15

    We have designed and implemented a neutral metal vapor injector on the SuperEBIT high-energy electron beam ion trap at the Lawrence Livermore National Laboratory. A horizontally directed vapor of a europium metal is created using a thermal evaporation technique. The metal vapor is then spatially collimated prior to injection into the trap. The source's form and quantity constraints are significantly reduced making plasmas out of metal with vapor pressures ≤10{sup −7} Torr at ≥1000 °C more obtainable. A long pulsed or constant feed metal vapor injection method adds new flexibility by varying the timing of injection and rate of material being introduced into the trap.

  10. Ion permeabilities in mouse sperm reveal an external trigger for SLO3-dependent hyperpolarization.

    Directory of Open Access Journals (Sweden)

    Julio C Chávez

    Full Text Available Unlike most cells of the body which function in an ionic environment controlled within narrow limits, spermatozoa must function in a less controlled external environment. In order to better understand how sperm control their membrane potential in different ionic conditions, we measured mouse sperm membrane potentials under a variety of conditions and at different external K(+ concentrations, both before and after capacitation. Experiments were undertaken using both wild-type, and mutant mouse sperm from the knock-out strain of the sperm-specific, pH-sensitive, SLO3 K(+ channel. Membrane voltage data were fit to the Goldman-Hodgkin-Katz equation. Our study revealed a significant membrane permeability to both K(+ and Cl(- before capacitation, as well as Na(+. The permeability to both K(+ and Cl(- has the effect of preventing large changes in membrane potential when the extracellular concentration of either ion is changed. Such a mechanism may protect against undesired shifts in membrane potential in changing ionic environments. We found that a significant portion of resting membrane potassium permeability in wild-type sperm was contributed by SLO3 K(+ channels. We also found that further activation of SLO3 channels was the essential mechanism producing membrane hyperpolarization under two separate conditions, 1 elevation of external pH prior to capacitation and 2 capacitating conditions. Both conditions produced a significant membrane hyperpolarization in wild-type which was absent in SLO3 mutant sperm. Hyperpolarization in both conditions may result from activation of SLO3 channels by raising intracellular pH; however, demonstrating that SLO3-dependent hyperpolarization is achieved by an alkaline environment alone shows that SLO3 channel activation might occur independently of other events associated with capacitation. For example sperm may undergo stages of membrane hyperpolarization when reaching alkaline regions of the female genital tract

  11. Evaluation of a novel PTFE material for separation and preconcentration of trace levels of metal ions in sequential injection (SI) and sequential injection lab-on-valve (SI-LOV) systems interfaced with detection by ETAAS

    DEFF Research Database (Denmark)

    Long, Xiangbao; Chomchoei, Roongrat; Gała, Piotr

    The operational characteristics of a novel PTFE bead material, granular Algoflon®, used for separation and preconcentration of metal ions via adsorption of on-line generated non-charged metal complexes, were evaluated in a sequential injection (SI) system furnished with an external packed column...... and in a sequential injection lab-on-valve (SI-LOV) system. Employed for the determination of cadmium(II), complexed with diethyldithiophosphate (DDPA), and detection by electrothermal atomic absorption spectrometry (ETAAS), its performance was compared to that of a previously used material, Aldrich PTFE, which had...... demonstrated that PTFE was the most promising for solid-state pretreatments. By comparing the two materials, the Algoflon® beads exhibited much higher sensitivity (1.6107 versus 0.2956 μg l-1 per integrated absorbance (s)), and better retention efficiency (82% versus 74%) and enrichment factor (20.8 versus 17...

  12. Internal and External Temperature Monitoring of a Li-Ion Battery with Fiber Bragg Grating Sensors

    Directory of Open Access Journals (Sweden)

    Susana Novais

    2016-08-01

    Full Text Available The integration of fiber Bragg grating (FBG sensors in lithium-ion cells for in-situ and in-operando temperature monitoring is presented herein. The measuring of internal and external temperature variations was performed through four FBG sensors during galvanostatic cycling at C-rates ranging from 1C to 8C. The FBG sensors were placed both outside and inside the cell, located in the center of the electrochemically active area and at the tab-electrode connection. The internal sensors recorded temperature variations of 4.0 ± 0.1 °C at 5C and 4.7 ± 0.1 °C at 8C at the center of the active area, and 3.9 ± 0.1 °C at 5C and 4.0 ± 0.1 °C at 8C at the tab-electrode connection, respectively. This study is intended to contribute to detection of a temperature gradient in real time inside a cell, which can determine possible damage in the battery performance when it operates under normal and abnormal operating conditions, as well as to demonstrate the technical feasibility of the integration of in-operando microsensors inside Li-ion cells.

  13. Internal and External Temperature Monitoring of a Li-Ion Battery with Fiber Bragg Grating Sensors.

    Science.gov (United States)

    Novais, Susana; Nascimento, Micael; Grande, Lorenzo; Domingues, Maria Fátima; Antunes, Paulo; Alberto, Nélia; Leitão, Cátia; Oliveira, Ricardo; Koch, Stephan; Kim, Guk Tae; Passerini, Stefano; Pinto, João

    2016-08-30

    The integration of fiber Bragg grating (FBG) sensors in lithium-ion cells for in-situ and in-operando temperature monitoring is presented herein. The measuring of internal and external temperature variations was performed through four FBG sensors during galvanostatic cycling at C-rates ranging from 1C to 8C. The FBG sensors were placed both outside and inside the cell, located in the center of the electrochemically active area and at the tab-electrode connection. The internal sensors recorded temperature variations of 4.0 ± 0.1 °C at 5C and 4.7 ± 0.1 °C at 8C at the center of the active area, and 3.9 ± 0.1 °C at 5C and 4.0 ± 0.1 °C at 8C at the tab-electrode connection, respectively. This study is intended to contribute to detection of a temperature gradient in real time inside a cell, which can determine possible damage in the battery performance when it operates under normal and abnormal operating conditions, as well as to demonstrate the technical feasibility of the integration of in-operando microsensors inside Li-ion cells.

  14. Numerical Study on the Flow Length in an Injection Molding Process with an External Air-Heating Step

    Directory of Open Access Journals (Sweden)

    Thanh Trung Do

    2017-04-01

    Full Text Available In this study, an external gas-assisted mold temperature control combined with water cooling was applied to achieve rapid mold-surface temperature control for observing the melt flow length in the thin-wall injection molding process. Variable part-thickness values of 0.2 mm, 0.4 mm, and 0.6 mm were used. Through a simulation and experiment, the injection molding process was achieved by using ABS and stamp insert temperatures ranging from 30 to 150 °C. In the simulation, when the stamp temperature was raised from 90 to 150 °C with part thickness of 0.2 mm, 0.4 mm, and 0.6 mm, the melt flow length increased by approximately 25.0%, 19.6%, and 12.8%, respectively. When the stamp temperature was higher than the glass-transition temperature of ABS, the improvement in the melt flow length was clearer, especially in the thinner part. In the experiment, the positive effect of stamp temperature was demonstrated; however, the improvement in the melt flow length was slightly different compared with the simulation owing to the heat transfer between the hot stamp and the environment.

  15. NEUROCHEMICAL LESIONING IN THE RAT-BRAIN WITH IONTOPHORETIC INJECTION OF THE 1-METHYL-4-PHENYLPYRIDINIUM ION (MPP+)

    NARCIS (Netherlands)

    TERHORST, GJ; KNIGGE, MF; VANDERWAL, A

    1992-01-01

    Iontophoretic injections of the 1-methyl-4-phenylpyridinium ion (MPP+) were made in the dopaminergic part of the substantia nigra to see whether this injection technique could be used for inducing localized neurochemical lesions in dopaminergic cell groups and to assess the effects of MPP+ on non-do

  16. Ion-cage interpretation for the structural and dynamic changes of ionic liquids under an external electric field.

    Science.gov (United States)

    Shi, Rui; Wang, Yanting

    2013-05-01

    In many applications, ionic liquids (ILs) work in a nonequilibrium steady state driven by an external electric field. However, how the electric field changes the structure and dynamics of ILs and its underlying mechanism still remain poorly understood. In this paper, coarse-grained molecular dynamics simulations were performed to investigate the structure and dynamics of 1-ethyl-3-methylimidazolium nitrate ([EMIm][NO3]) under a static electric field. The ion cage structure was found to play an essential role in determining the structural and dynamic properties of the IL system. With a weak or moderate electric field (0-10(7) V/m), the external electric field is too weak to modify the ion cage structure in an influential way and thus the changes of structural and dynamic properties are negligible. With a strong electric field (10(7)-10(9) V/m) applied, ion cages expand and deform apparently, leading to the increase of ion mobility and self-diffusion coefficient with electric field, and the self-diffusion of ions along the electric field becomes faster than the other two directions due to the anisotropic deformation of ion cages. In addition, the Einstein relation connecting diffusion and mobility breaks down at strong electric fields, and it also breaks down for a single ion species even at moderate electric fields (linear-response region).

  17. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole.

    Science.gov (United States)

    Rodrigues, G; Becker, R; Hamm, R W; Baskaran, R; Kanjilal, D; Roy, A

    2014-02-01

    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged (238)U(40+) (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  18. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, G., E-mail: gerosro@gmail.com; Kanjilal, D.; Roy, A. [Inter University Accelerator Centre, Aruna Asaf Ali Marg, New Delhi (India); Becker, R. [Institut fur Angewandte Physik der Universitaet, D-60054 Frankfurt/M (Germany); Hamm, R. W. [R and M Technical Enterprises, Inc., 4725 Arlene Place, Pleasanton, California 94566 (United States); Baskaran, R. [Indira Gandhi Centre for Atomic Research, Kalpakkam, Tamilnadu (India)

    2014-02-15

    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged {sup 238}U{sup 40+} (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  19. The direct injection of intense ion beams from a high field electron cyclotron resonance ion source into a radio frequency quadrupole

    Science.gov (United States)

    Rodrigues, G.; Becker, R.; Hamm, R. W.; Baskaran, R.; Kanjilal, D.; Roy, A.

    2014-02-01

    The ion current achievable from high intensity ECR sources for highly charged ions is limited by the high space charge. This makes classical extraction systems for the transport and subsequent matching to a radio frequency quadrupole (RFQ) accelerator less efficient. The direct plasma injection (DPI) method developed originally for the laser ion source avoids these problems and uses the combined focusing of the gap between the ion source and the RFQ vanes (or rods) and the focusing of the rf fields from the RFQ penetrating into this gap. For high performance ECR sources that use superconducting solenoids, the stray magnetic field of the source in addition to the DPI scheme provides focusing against the space charge blow-up of the beam. A combined extraction/matching system has been designed for a high performance ECR ion source injecting into an RFQ, allowing a total beam current of 10 mA from the ion source for the production of highly charged 238U40+ (1.33 mA) to be injected at an ion source voltage of 60 kV. In this design, the features of IGUN have been used to take into account the rf-focusing of an RFQ channel (without modulation), the electrostatic field between ion source extraction and the RFQ vanes, the magnetic stray field of the ECR superconducting solenoid, and the defocusing space charge of an ion beam. The stray magnetic field is shown to be critical in the case of a matched beam.

  20. Study of argon additive in a beam injection type negative ion source using VUV emission spectroscopy

    OpenAIRE

    Nakada, Naoki; Fukumasa, Osamu

    2006-01-01

    Effects of Ar addition are studied by using a beam injection type negative ion source. With adding Ar, I_ increases at low base H_2 pressure. At high base H_2 pressure, however, I_ decreases. VUV emission intensities also decrease at high base pressure. In other words, Ar addition is adverse effect for production of H_2 (v''). Therefore, decrease in I_ is caused by decrease in H_2 (v''). In D_2 plasmas, variation patterns of plasma parameters and VUV intensities by Ar addition are nearly the ...

  1. Distribution of intravascularly injected lanthanum ions in ganglia of the autonomic nervous system of the rat.

    Science.gov (United States)

    DePace, D M

    1984-12-01

    Intravascular injection of lanthanum revealed that tight junctions of capillaries in sympathetic ganglia are impermeable to small ions and thus behave like capillaries of the blood-brain barrier. The failure of lanthanum to accumulate in the extracellular space suggests that fenestrated capillaries are not as ion-permeable as use of horseradish peroxidase (HRP) by some authors has indicated. A possible toxic action associated with high concentrations of HRP may be responsible for the high permeability of this substance. Testing with lanthanum demonstrated that sympathetic ganglia possess anatomic features that provide a hematic barrier. The blood-ganglion barrier resembles, but has not yet been demonstrated to be as absolute as the blood-brain barrier.

  2. Molecular effect on equilibrium charge-state distributions. [of nitrogen ions injected through carbon foil

    Science.gov (United States)

    Wickholm, D.; Bickel, W. S.

    1976-01-01

    The paper describes an experiment consisting of the acceleration of N(+) and N2(+) ions to energies between 0.25 and 1.75 MeV and their injection through a thin carbon foil, whereupon they were charge-state analyzed with an electrostatic analyzer. A foil-covered electrically suppressed Faraday cup, connected to a stepping motor, moved in the plane of the dispersed beams. The Faraday cup current, which was proportional to the number of incident ions, was sent to a current digitizer and computer programmed as a multiscaler. The energy-dependent charge-state fractions, the mean charge and the distribution width were calculated. It was shown that for incident atoms, the charge state distribution appeared to be spread over more charge states, while for the incident molecules, there was a greater fraction of charge states near the mean charge.

  3. Measurements on Pb27+ Sources for the CERN Heavy Ion Injection Chain

    CERN Document Server

    Chamings, J A

    2004-01-01

    CERN, the world's largest particle physics laboratory near Geneva, is currently in the process of building the Large Hadron Collider (LHC). Lead-208 will be used in this accelerator and to meet the injection requirements much work is required to find a suitable and reliable heavy ion source. The work in this report covers two ion sources, the Laser Ion Source (LIS), and the Electron Cyclotron Resonance Ion Source (ECRIS). An emittance measurement, using a pepper pot and CCD camera, was completed on the recently re-installed LIS, measured and analysed to be 140mm.mrad un-normalised and 0.8mm.mrad normalised 4rms for the maximum intensity charge state, Pb27+. A Visual Basic Program was modified to allow Charge State Distribution (CSD) and other scans of the ECRIS at CERN to be taken. Chapter 5 presents the results of the CSD scans taken. This program provided a new method to take 1 dimensional transverse beam profiles. From this a direct emittance measurement was formed for the first time since the source was o...

  4. Experimental study of the dependence of beam current on injection magnetic field in 6.4 GHz ECR ion source

    Indian Academy of Sciences (India)

    G S Taki; P R Sarma; D K Chakraborty; R K Bhandari; P K Ray

    2006-09-01

    The ion current from an electron cyclotron resonance (ECR) heavy ion source depends on the confining axial and radial magnetic fields. Some efforts were made by earlier workers to investigate magnetic field scaling on the performance of the ECR source. In order to study the dependence of the ion current on the injection magnetic field in the 6.4 GHz ECR source, we have measured the current by varying the peak injection field and have inferred that the variation of the current is exponential up to our maximum design injection field of 7.5 kG. An attempt has been made to understand this exponential nature on the basis of ion confinement time.

  5. Students' Understanding of External Representations of the Potassium Ion Channel Protein, Part I: Affordances and Limitations of Ribbon Diagrams, Vines, and Hydrophobic/Polar Representations

    Science.gov (United States)

    Harle, Marissa; Towns, Marcy H.

    2012-01-01

    Research on external representations in biochemistry has uncovered student difficulties in comprehending and interpreting external representations. This project focuses on students' understanding of three external representations of the potassium ion channel protein. This is part I of a two-part study, which focuses on the affordances and…

  6. Injection optimization in a heavy-ion synchrotron using genetic algorithms

    Science.gov (United States)

    Appel, S.; Boine-Frankenheim, O.; Petrov, F.

    2017-04-01

    The control of the beam loss induced dynamic pressure is one of the most challenging problems for synchrotrons operated with high intensity beams of intermediate charge state ions. This loss-induced vacuum degradation and associated life-time reduction is one of the key intensity limiting factors. Beam loss during Multi-Turn Injection (MTI) can trigger the pressure bump instability. An optimized injection can relax the dynamic vacuum problem, but is also crucial to fill the available machine acceptance. A numerical model has been developed to describe the intensity limitation due to loss-induced vacuum degradation. In order to optimize the multi-turn injection for given initial losses, a genetic algorithm based optimization has been performed. For the SIS18 synchrotron at GSI the optimization resulted in a significant improvement of MTI performance and subsequent transmission for intense beams. A range of suitable injector brilliances for given initial loss could be defined. This information is crucial for the layout of the injector upgrade for FAIR. The effect of transverse space charge force on MTI has been included in the optimization studies.

  7. SPS Injection and Beam Quality for LHC Heavy Ions With 150 ns Kicker Rise Time

    CERN Document Server

    Goddard, Brennan; Ducimetière, Laurent; Kotzian, Gerd; Uythoven, Jan; Velotti, Francesco

    2016-01-01

    As part of the LHC Injectors Upgrade project for LHC heavy ions, the SPS injection kicker system rise time needs reduction below its present 225 ns. One technically challenging option under consideration is the addition of fast Pulse Forming Lines in parallel to the existing Pulse Forming Networks for the 12 kicker magnets MKP-S, targeting a system field rise time of 100 ns. An alternative option is to optimise the system to approach the existing individual magnet field rise time (2-98%) of 150 ns. This would still significantly increase the number of colliding bunches in LHC while minimising the cost and effort of the system upgrade. The observed characteristics of the present system are described, compared to the expected system rise time, together with results of simulations and measurements with 175 and 150 ns injection batch spacing. The expected beam quality at injection into LHC is quantified, with the emittance growth and simulated tail population taking into account expected jitter and synchronisatio...

  8. Operating characteristics of a new ion source for KSTAR neutral beam injection system.

    Science.gov (United States)

    Kim, Tae-Seong; Jeong, Seung Ho; Chang, Doo-Hee; Lee, Kwang Won; In, Sang-Ryul

    2014-02-01

    A new positive ion source for the Korea Superconducting Tokamak Advanced Research neutral beam injection (KSTAR NBI-1) system was designed, fabricated, and assembled in 2011. The characteristics of the arc discharge and beam extraction were investigated using hydrogen and helium gas to find the optimum operating parameters of the arc power, filament voltage, gas pressure, extracting voltage, accelerating voltage, and decelerating voltage at the neutral beam test stand at the Korea Atomic Energy Research Institute in 2012. Based on the optimum operating condition, the new ion source was then conditioned, and performance tests were primarily finished. The accelerator system with enlarged apertures can extract a maximum 65 A ion beam with a beam energy of 100 keV. The arc efficiency and optimum beam perveance, at which the beam divergence is at a minimum, are estimated to be 1.0 A/kW and 2.5 uP, respectively. The beam extraction tests show that the design goal of delivering a 2 MW deuterium neutral beam into the KSTAR Tokamak plasma is achievable.

  9. Optically controllable dual-mode switching in single-mode Fabry-Pérot laser diode subject to one side-mode feedback and external single mode injection

    Science.gov (United States)

    Wu, Jian-Wei; Won, Yong Hyub

    2017-06-01

    In this paper, broadly tunable dual-mode lasing system is presented and demonstrated based on single-mode Fabry-Pérot laser diode subject to the feedback of one side mode amplified by an erbium-doped fiber amplifier in the external feedback cavity. The spacing between two resonance modes in output lasing spectrum is broadly tuned by introducing differently amplified side mode into the single-mode laser via the external cavity consisted of amplifier, filter, and polarization controller so that two difference frequencies of 1 THz and 0.6 THz are given to display the tunable behavior of dual-mode emission in this work. Therefore, under an external injection mode into the laser condition, the power dependent injection locking and optical bistability of generated dual-mode emission are discussed in detail. At different wavelength detunings, the emitted two resonance modes including the dominant and feedback modes are switched to on- or off-state by selecting proper high-low power level of the external injection mode. As a consequence, the maximum value of achieved dual-mode on-off ratio is as high as up to 45 dB.

  10. Upgrade of the SPS Injection Kicker System for the LHC High Luminosity Operation with Heavy Ion Beam

    CERN Document Server

    Kramer, T; Goddard, B; Ducimetière, L; Sermeus, L; Uythoven, J; Velotti, FM

    2014-01-01

    In the context of the LHC High Luminosity Upgrade project a performance upgrade for heavy ions is envisaged. One of the performance limitations is the rise time of the present SPS injection kicker system MKP. A reduction of the rise time for lead ions was studied in line with a modification of the whole injection system. This paper briefly describes the different rise time options studied for an initially proposed dedicated ion kicker system MKP-I, focuses however on a cost effective alternative using the presently installed 12 MKPS magnets connected to a new fast pulse forming line. As only 12 out of the 16 injection kicker magnets would be fast enough to be used in an upgraded system, additional deflection has to be provided by the septa. The beam optics for that variant is highlighted and first requirements for the septum elements are stipulated. The paper concludes with a failure analysis of the proposed scheme.

  11. Beam Loss Control for the Unstripped Ions from the PS2 Charge Exchange Injection

    CERN Document Server

    Bartmann, W; Benedikt, M; Goddard, B; Kramer, T; Papaphilippou, Y; Vincke, Hel

    2010-01-01

    Control of beam losses is an important aspect of the H-injection system for the PS2, a proposed replacement of the CPS in the CERN injector complex. H- ions may pass the foil unstripped or be partially stripped to excited H0 states which may be stripped in the subsequent strong-field chicane magnet. Depending on the choice of the magnetic field, atoms in the ground and first excited states can be extracted and dumped. The conceptual design of the waste beam handling is presented, including local collimation and the dump line, both of which must take into account the divergence of the beam from stripping in fringe fields. Beam load estimates and activation related requirements of the local collimators and dump are briefly discussed.

  12. Analytical Method Development & Validation for Related Substances Method of Busulfan Injection by Ion Chromatography Method

    Directory of Open Access Journals (Sweden)

    Rewaria S

    2013-05-01

    Full Text Available A new simple, accurate, precise and reproducible Ion chromatography method has been developed forthe estimation of Methane sulfonic acid in Busulfan injectable dosage. The method which is developedis also validated in complete compliance with the current regulatory guidelines by using well developedanalytical method validation techniques and tools which comprises with the analytical method validationparameters like Linearity, LOD and LOQ determination, Accuracy, Method precision, Specificity,System suitability, Robustness, Ruggedness etc. by adopting the current method the linearity obtained isnear to 0.999 and thus this shows that the method is capable to give a good detector response, therecovery calculated was within the range of 85% to 115% of the specification limits.

  13. Flow-Injection Amperometric Determination of Tacrine based on Ion Transfer across a Water–Plasticized Polymeric Membrane Interface

    OpenAIRE

    Rueda, C.; Joaquin A. Ortuño

    2007-01-01

    A flow-injection pulse amperometric method for determining tacrine, based on ion transfer across a plasticized poly(vinyl chloride) (PVC) membrane, was developed. A four-electrode potentiostat with ohmic drop compensation was used, while a flow-through cell incorporated the four electrodes and the membrane, which contained tetrabutylammonium tetraphenylborate. The influence of the applied potential and of the flow-injection variables on the determination of tacrine was studied. In the selecte...

  14. Electron self-injection for the acceleration in laser-pulse-wakes in the presence of a `strong' external magnetic field

    CERN Document Server

    Zhidkov, A; Masuda, S; Oishi, Y; Fujii, T; Kodama, R

    2012-01-01

    An external static magnetic field with its strength B~10T may result in the laser wake wave-breaking upon changing the electron motion in the vicinity of maximal density ramp of a wave period. This, as shown by numerical simulations, can change the resonance character of the electron self-injection in the laser wake-field; a total charge loaded in the acceleration phase of laser pulse wake can be controlled by a proper choice of the magnetic field strength.

  15. Flow injection spectrophotometry coupled with a crushed barium sulfate reactor column for the determination of sulfate ion in water samples

    OpenAIRE

    Burakham,Rodjana; Higuchi, Keiro; Oshima, Mitsuko; Grudpan, Kate; Motomizu, Shoji

    2004-01-01

    A new type of a reactor column, a crushed BaSO4 reactor column used for the flow injection spectrophotometric determination of sulfate ion using the exchange reaction of sulfate ion and barium-dimethylsulfonazo III is proposed. The column is very simple and economical. It can be continuously used for 8 h before washing with water for repeated usage of at least 1 month. The procedure is sensitive. Application to various water samples was demonstrated.

  16. Temporal and Spatial Evolution of Energetic Ion Injections in the Inner Magnetosphere: Multi-Point Observations of a Substorm Event.

    Science.gov (United States)

    Gkioulidou, M.; Ohtani, S.; Mitchell, D. G.; Reeves, G. D.; Ukhorskiy, A. Y.; Turner, D. L.; Gjerloev, J. W.; Nose, M.; Koga, K.; Rodriguez, J. V.; Lanzerotti, L. J.

    2014-12-01

    Plasma transport and energization of ions in the magnetotail has been shown to largely occur in the form of injections of hot plasma, localized in MLT, associated with bursty bulk flows and sharp dipolarizations of the magnetic field. However, the relationship of these transient tail phenomena to energetic particle injections into the inner magnetosphere is not well understood. Recent results by the RBSPICE instrument of the Van Allen Probes mission showed that the occurrence of energetic ion injections inside geosynchronous orbit can be very frequent throughout the main phase of a geomagnetic storm, and indicated that the contribution of such injections to the ring current buildup could be substantial. Understanding the formation and evolution of energetic ion injections in the inner magnetosphere and their relationship to transient phenomena in the tail is, therefore, of great importance. In order to differentiate between temporal and spatial variations, it is essential to investigate injections via multi-point observations. We study a substorm event that occurred during a small storm (Dst ~-40 nT), where two injections of energetic ions (50 - 300 keV), 10 minutes apart, were observed by RBSPICE instrument inside geosynchronous orbit, and six LANL and two GOES spacecraft at geosynchronous orbit. Geosynchronous spacecraft ETS-8, at a similar MLT with Van Allen Probe B, also observed the dipolarization signatures associated with these two injections. At the same time, two THEMIS spacecraft were monitoring the night-side magnetosphere at ~ 10 RE. Using ground-based magnetometer data, we are able to identify the eastward and westward edges of the current wedge associated with each one of these injections. The two injections, as observed in the inner magnetosphere, exhibit distinct differences in their dipolarization signatures as well as their duration. With all the above data at hand, we investigate the inward propagation of the injections into the inner

  17. Dynamics of 1.55 μm Wavelength Single-Mode Vertical-Cavity Surface-Emitting Laser Output under External Optical Injection

    Directory of Open Access Journals (Sweden)

    Kyong Hon Kim

    2012-01-01

    Full Text Available We review the temporal dynamics of the laser output spectrum and polarization state of 1.55 μm wavelength single-mode (SM vertical-cavity surface-emitting lasers (VCSELs induced by external optical beam injection. Injection of an external continuous-wave laser beam to a gain-switched SM VCSEL near the resonance wavelength corresponding to its main polarization-mode output was critical for improvement of its laser pulse generation characteristics, such as pulse timing-jitter reduction, linewidth narrowing, pulse amplitude enhancement, and pulse width shortening. Pulse injection of pulse width shorter than the cavity photon lifetime into the SM VCSEL in the orthogonal polarization direction with respect to its main polarization mode caused temporal delay of the polarization recovery after polarization switching (PS, and its delay was found to be the minimum at an optimized bias current. Polarization-mode bistability was observed even in the laser output of an SM VCSEL of a standard circularly cylindrical shape and used for all-optical flip-flop operations with set and reset injection pulses of very low pulse energy of order of the 3.5~4.5 fJ.

  18. Control of Internal and External Short Circuits in Lithium Ion and Lithium Batteries Project

    Data.gov (United States)

    National Aeronautics and Space Administration — NASA has identified needs for compact high-energy-density primary and secondary batteries. Lithium and Lithium Ion cells, respectively, are meeting these needs for...

  19. Integration of XRF spectrometer for simultaneous and/or complementary use with PIXE at the external ion beam analysis setup

    Energy Technology Data Exchange (ETDEWEB)

    Fazinic, S.; Cosic, D.; Jaksic, M. [Laboratory for lon Beam Interactions, Division of Experimental Physics, Rudjer Boskovic Institute, Zagreb (Croatia); Migliori, A.; Karydas, A.G. [Nuclear Spectrometry and Applications Laboratory, International Atomic Energy Agency (IAEA), Vienna (Austria); Desnica, V. [Laboratory for Science and Technology in Art, Academy of Fine Arts in Zagreb, Zagreb (Croatia); Mudronja, D. [Natural Science Laboratory, Croatian Conservation Institute, Zagreb (Croatia)

    2013-07-01

    Full text: The Rudjer Boskovic Institute Tandem Accelerator Facility is equipped with a number of end-stations dedicated to ion beam analysis (IBA), modification of materials and nuclear physics experiments. IBA is performed at the: (1) nuclear microbeam, (2) broad-beam in-vacuum and (3) external beam end-stations. Several lBA techniques can be used simultaneously, Particle Induced X-ray Emission (PIXE) and Particle Induced Gamma-ray Emission (PIGE) at the external beam end-station, and additionally Rutherford Backscattering Spectroscopy (RBS) at the in-vacuum end-station. X-ray fluorescence (XRF) analysis is a technique complementary to PIXE. Both techniques offer high analytical potential for multi-elemental investigations and material characterization. Due to different excitation mechanisms, PIXE generally exhibits higher sensitivity for lighter elements and XRF for heavier, whereas they also have different in-sample depth sensitivities. Although they use different excitation sources, both techniques can use the same data acquisition modules. With the development of miniature, low power and lightweight X-ray tubes it is possible to incorporate an X-ray source within the IBA setup and combine the two techniques for simultaneous use. In this work, the unification of the PIXE and XRF techniques at the RBI external ion beam analysis setup has been investigated and the results are discussed. This has been done by installing a transmission miniature X-ray tube at the end-station. The tube has been properly positioned in order to irradiate the same spot on the sample as the ion beam used for PIXE/PIGE measurements. Our home made data acquisition system SPECTOR, used regularly for the IBA measurements, has been also used to acquire the XRF spectra. At first, the X-ray tube has been installed at the in-vacuum IBA station, and then to the external beam end-station. Test measurements have been carried out on various standard reference materials using both systems and the

  20. Recent developments of ion beam induced luminescence at the external scanning microbeam facility of the LABEC laboratory in Florence

    Energy Technology Data Exchange (ETDEWEB)

    Colombo, E. [INFN sezione di Torino, via P.Giuria 1, 10125 Torino (Italy); Dipartimento di Fisica and Centro di Eccellenza NIS, Universita di Torino, via P. Giuria 1, 10125 Torino (Italy); Calusi, S. [INFN sezione di Torino, via P.Giuria 1, 10125 Torino (Italy); Dipartimento di Fisica, Universita and INFN Sez.di Firenze, via Sansone 1, 50019 Sesto Fiorentino, Firenze (Italy); Cossio, R. [Dipartimento di Scienze Mineralogiche e Petrologiche, via Valperga Caluso, 35, 10125 Torino (Italy); Giuntini, L. [Dipartimento di Fisica, Universita and INFN Sez.di Firenze, via Sansone 1, 50019 Sesto Fiorentino, Firenze (Italy); Giudice, A. [Dipartimento di Fisica and Centro di Eccellenza NIS, Universita di Torino, via P. Giuria 1, 10125 Torino (Italy); Lo Mando, P.A. [Dipartimento di Fisica, Universita and INFN Sez.di Firenze, via Sansone 1, 50019 Sesto Fiorentino, Firenze (Italy); Manfredotti, C. [INFN sezione di Torino, via P.Giuria 1, 10125 Torino (Italy); Dipartimento di Fisica and Centro di Eccellenza NIS, Universita di Torino, via P. Giuria 1, 10125 Torino (Italy); Massi, M.; Mirto, F.A. [Dipartimento di Fisica, Universita and INFN Sez.di Firenze, via Sansone 1, 50019 Sesto Fiorentino, Firenze (Italy); Vittone, E. [INFN sezione di Torino, via P.Giuria 1, 10125 Torino (Italy); Dipartimento di Fisica and Centro di Eccellenza NIS, Universita di Torino, via P. Giuria 1, 10125 Torino (Italy)], E-mail: vittone@to.infn.it

    2008-04-15

    A new ionoluminescence (IL) apparatus has been successfully installed at the external scanning microbeam facility of the 3 MV Tandetron accelerator of the INFN LABEC in Firenze; the apparatus for photon detection has been fully integrated in the existing ion beam analysis (IBA) set-up, for the simultaneous acquisition of IL and PIXE/PIGE/BS spectra and maps. The potential of the new set-up is illustrated in this paper by some results extracted by the analysis of art objects and advanced semiconductor materials. In particular, the adequacy of the new IBA set-up in the field of cultural heritage is pointed out by the coupled PIXE/IL micro-analysis of a lapis lazuli stone; concerning applications in material science, IL spectra from a N doped diamond sample were acquired and compared with CL analyses to evaluate the relevant sensitivities and the effect of ion damage.

  1. Recent developments of ion beam induced luminescence at the external scanning microbeam facility of the LABEC laboratory in Florence

    Science.gov (United States)

    Colombo, E.; Calusi, S.; Cossio, R.; Giuntini, L.; Giudice, A. Lo; Mandò, P. A.; Manfredotti, C.; Massi, M.; Mirto, F. A.; Vittone, E.

    2008-04-01

    A new ionoluminescence (IL) apparatus has been successfully installed at the external scanning microbeam facility of the 3 MV Tandetron accelerator of the INFN LABEC in Firenze; the apparatus for photon detection has been fully integrated in the existing ion beam analysis (IBA) set-up, for the simultaneous acquisition of IL and PIXE/PIGE/BS spectra and maps. The potential of the new set-up is illustrated in this paper by some results extracted by the analysis of art objects and advanced semiconductor materials. In particular, the adequacy of the new IBA set-up in the field of cultural heritage is pointed out by the coupled PIXE/IL micro-analysis of a lapis lazuli stone; concerning applications in material science, IL spectra from a N doped diamond sample were acquired and compared with CL analyses to evaluate the relevant sensitivities and the effect of ion damage.

  2. Biological Effects of Drug-Free Alginate Beads Cross-Linked by Copper Ions Prepared Using External Ionotropic Gelation.

    Science.gov (United States)

    Pavelková, M; Kubová, K; Vysloužil, J; Kejdušová, M; Vetchý, D; Celer, V; Molinková, D; Lobová, D; Pechová, A; Vysloužil, J; Kulich, P

    2016-08-08

    External ionotropic gelation offers a unique possibility to entrap multivalent ions in a polymer structure. The aim of this experimental study was to prepare new drug-free sodium alginate (ALG) particles cross-linked by Cu(2+) ions and to investigate their technological parameters (particle size, sphericity, surface topology, swelling capacity, copper content, release of Cu(2+) ions, mucoadhesivity) and biological activity (cytotoxicity and efficiency against the most common vaginal pathogens-Herpes simplex, Escherichia coli, Candida albicans) with respect to potential vaginal administration. Beads prepared from NaALG dispersions (3 or 4%) were cross-linked by Cu(2+) ions (0.5 or 1.0 M CuCl2) using external ionotropic gelation. Prepared mucoadhesive beads with particle size over 1000 μm exhibited sufficient sphericity (all ˃0.89) and copper content (214.8-249.07 g/kg), which increased with concentration of polymer and hardening solution. Dissolution behaviour was characterized by extended burst effect, followed by 2 h of copper release. The efficiency of all samples against the most common vaginal pathogens was observed at cytotoxic Cu(2+) concentrations. Anti-HSV activity was demonstrated at a Cu(2+) concentration of 546 mg/L. Antibacterial activity of beads (expressed as minimum inhibition concentration, MIC) was influenced mainly by the rate of Cu(2+) release which was controlled by the extent of swelling capacity. Lower MIC values were found for E. coli in comparison with C. albicans. Sample ALG-3_1.0 exhibited the fastest copper release and was proved to be the most effective against both bacteria. This could be a result of its lower polymer concentration in combination with smaller particle size and thus larger surface area.

  3. Commissioning and Operation of the FNAL Front end Injection Line and Ion Sources.

    Energy Technology Data Exchange (ETDEWEB)

    Karns, Patrick R. [Indiana Univ., Bloomington, IN (United States)

    2015-09-01

    This thesis documents the efforts made in commissioning and operating the RFQ Injection Line (RIL) as a replacement for the Cockcroft Walton front end. The Low Energy Beam Transport (LEBT) was assembled and tested with multiwire position and emittance monitor measurements. The Radio Frequency Quadrupole (RFQ) commissioning was completed with the same measurements as well as output beam energy measurements that showed it initially accelerated beam only to 700 keV, which was 50 keV lower than the design energy. Working with the manufacturer solutions were found and instituted to continue testing. The Medium Energy Beam Transport (MEBT) was then connected as the RIL was installed as the new front end of Linac. Testing gave way to operation when the new front end was used as the source of all High Energy Physics (HEP) beam for Fermi National Accelerator Laboratory (FNAL). The magnetron ion source that provides the H- beam for the front end required several changes and eventual upgrades to operate well; such as new source operating points for vacuum pressure and cesium admixture, and new materials for critical source components. Further research was conducted on the cathode geometry and nitrogen doping of the hydrogen gas as well as using solid state switches for the extractor system high voltage.

  4. Commissioning and operation of the FNAL front end injection line and ion sources

    Science.gov (United States)

    Karns, Patrick R.

    This thesis documents the efforts made in commissioning and operating the RFQ Injection Line (RIL) as a replacement for the Cockcroft Walton front end. The Low Energy Beam Transport (LEBT) was assembled and tested with multiwire position and emittance monitor measurements. The Radio Frequency Quadrupole (RFQ) commissioning was completed with the same measurements as well as output beam energy measurements that showed it initially accelerated beam only to 700 keV, which was 50 keV lower than the design energy. Working with the manufacturer solutions were found and instituted to continue testing. The Medium Energy Beam Transport (MEBT) was then connected as the RIL was installed as the new front end of Linac. Testing gave way to operation when the new front end was used as the source of all High Energy Physics (HEP) beam for Fermi National Accelerator Laboratory (FNAL). The magnetron ion source that provides the H- beam for the front end required several changes and eventual upgrades to operate well; such as new source operating points for vacuum pressure and cesium admixture, and new materials for critical source components. Further research was conducted on the cathode geometry and nitrogen doping of the hydrogen gas as well as using solid state switches for the extractor system high voltage.

  5. Effect of external electric fields on the dielectronic recombination cross section of lithium and sodium like ions

    Energy Technology Data Exchange (ETDEWEB)

    Griffin, D.C.; Pindzola, M.S.; Bottcher, C.

    1985-03-01

    The effect of external electric fields on the dielectronic recombination cross section associated with the 2s ..-->.. 2p excitation in the Li like ions B/sup 2 +/, C/sup 3 +/, O/sup 5 +/, and Fe/sup 23 +/, and the 3s ..-->.. 3p excitation in the Na like ions Mg/sup +/, S/sup 5 +/, Cl/sup 6 +/, and Fe/sup 15 +/ has been studied in the configuration-average, distorted-wave approximation. By applying the linear-Stark approximation to the doubly-excited 2pnl and 3pnl Rydberg states in the presence of an external electric field, we study the systematics of field mixing effects on dielectronic recombination and determine the maximum field enhancement of the dielectronic recombination cross section. We find that the magnitude of the field enhancement decreases as we move up an isoelectronic sequence and is of the order of a factor of two or three in highly-ionized systems. In addition, we show that dielectronic recombination transitions through doubly-excited states near threshold can produce large narrow peaks in the cross section at low energies, which are especially prominent in high stages of ionization, and are not affected by the electric field.

  6. Ion optics of RHIC electron beam ion source

    Energy Technology Data Exchange (ETDEWEB)

    Pikin, A.; Alessi, J.; Beebe, E.; Kponou, A.; Okamura, M.; Raparia, D.; Ritter, J.; Tan, Y. [Brookhaven National Laboratory, Upton, New York 11973 (United States); Kuznetsov, G. [Budker Institute of Nuclear Physics, Novosibirsk 630090 (Russian Federation)

    2012-02-15

    RHIC electron beam ion source has been commissioned to operate as a versatile ion source on RHIC injection facility supplying ion species from He to Au for Booster. Except for light gaseous elements RHIC EBIS employs ion injection from several external primary ion sources. With electrostatic optics fast switching from one ion species to another can be done on a pulse to pulse mode. The design of an ion optical structure and the results of simulations for different ion species are presented. In the choice of optical elements special attention was paid to spherical aberrations for high-current space charge dominated ion beams. The combination of a gridded lens and a magnet lens in LEBT provides flexibility of optical control for a wide range of ion species to satisfy acceptance parameters of RFQ. The results of ion transmission measurements are presented.

  7. Ion confinement and transport in a toroidal plasma with externally imposed radial electric fields

    Science.gov (United States)

    Roth, J. R.; Krawczonek, W. M.; Powers, E. J.; Kim, Y. C.; Hong, H. Y.

    1979-01-01

    Strong electric fields were imposed along the minor radius of the toroidal plasma by biasing it with electrodes maintained at kilovolt potentials. Coherent, low-frequency disturbances characteristic of various magnetohydrodynamic instabilities were absent in the high-density, well-confined regime. High, direct-current radial electric fields with magnitudes up to 135 volts per centimeter penetrated inward to at least one-half the plasma radius. When the electric field pointed radially toward, the ion transport was inward against a strong local density gradient; and the plasma density and confinement time were significantly enhanced. The radial transport along the electric field appeared to be consistent with fluctuation-induced transport. With negative electrode polarity the particle confinement was consistent with a balance of two processes: a radial infusion of ions, in those sectors of the plasma not containing electrodes, that resulted from the radially inward fields; and ion losses to the electrodes, each of the which acted as a sink and drew ions out of the plasma. A simple model of particle confinement was proposed in which the particle confinement time is proportional to the plasma volume. The scaling predicted by this model was consistent with experimental measurements.

  8. Influence of an external magnetic field on damage by self-ion irradiation in Fe90Cr10 alloy

    Directory of Open Access Journals (Sweden)

    Fernando José Sánchez

    2016-12-01

    Full Text Available The effect of an external magnetic field (B=0.5 T on Fe90Cr10 specimens during Fe ion irradiation, has been investigated by means of Conversion Electron Mössbauer Spectroscopy (CEMS. The analysis has revealed significant differences in the average hyperfine magnetic field (=0.3 T between non-irradiated and irradiated samples as well as between irradiations made with B (w/ B and without B (w/o B. It is considered that these variations can be due to changes in the local environment around the probe nuclei (57Fe; where vacancies and Cr distribution play a role. The results indicate that the Cr distribution in the neighbourhood of the iron atoms could be changed by the application of an external field. This would imply that an external magnetic field may be an important parameter to take into account in predictive models for Cr behaviour in Fe–Cr alloys, and especially in fusion conditions where intense magnetic fields are required for plasma confinement.

  9. OCDMA PON supporting ONU inter-networking based on gain-switched Fabry-Pérot lasers with external dual-wavelength injection.

    Science.gov (United States)

    Liu, Jie; Zeng, Duoduo; Guo, Changjian; Xu, Lei; He, Sailing

    2010-10-25

    We propose and demonstrate an OCDMA-PON scheme with optical network unit (ONU) internetworking capability, which utilizes low-cost gain-switched Fabry-Pérot (GS-FP) lasers with external dual-wavelength injection as the pulse sources on the ONU side. The injection-generated optical pulses in two wavelengths from the same GS-FP laser are used separately for the PON uplink transmission and ONU internetworking. Experimental results based on a two-user OCDMA system confirm the feasibility of the proposed scheme. With OCDMA technologies, separate ONU-internetworking groups can be established using different optical codes. We also give experiment results to analyze the performance of the ONU-ONU transmission at different power of interference signals when two ONU-internetworking groups are present in the OCDMA-PON.

  10. Low Timing Jitter and Tunable Dual- Wavelength Picosecond Pulse Genera from a Fabry-Pérot Laser Diode with External Injection

    Institute of Scientific and Technical Information of China (English)

    YANG Yi-Biao; WANG Yun-Cai; ZHANG Ming-Jiang; LIANG Wei

    2007-01-01

    A novel scheme to generate tunable dual-wavelength optical pulses with low timing jitter at arbitrary repetition rates is proposed and demonstrated experimentally. The pulses are generated from a gain-switched Fabry-Perot laser diode with two external cw beams for injection seeding simultaneously. The cw light is generated by two independent distributed feedback laser diodes, and their wavelengths can be tuned independently by two temperature controllers. The dual-wavelength pulses with the pulse width of 57 ps, the timing jitter of 340 fs, are obtained. The sidemode-suppression ratio of the output pulses is better than 23 dB over a 10-nm wavelength tuning range.

  11. Angular-divergence calculation for Experimental Advanced Superconducting Tokamak neutral beam injection ion source based on spectroscopic measurements

    Energy Technology Data Exchange (ETDEWEB)

    Chi, Yuan, E-mail: jtext@hust.edu.cn [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China); Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Hu, Chundong [Institute of Plasma Physics, Chinese Academy of Sciences, Hefei 230031 (China); Zhuang, Ge [State Key Laboratory of Advanced Electromagnetic Engineering and Technology, Huazhong University of Science and Technology, Wuhan 430074 (China)

    2014-02-15

    Calorimetric method has been primarily applied for several experimental campaigns to determine the angular divergence of high-current ion source for the neutral beam injection system on the Experimental Advanced Superconducting Tokamak (EAST). A Doppler shift spectroscopy has been developed to provide the secondary measurement of the angular divergence to improve the divergence measurement accuracy and for real-time and non-perturbing measurement. The modified calculation model based on the W7AS neutral beam injectors is adopted to accommodate the slot-type accelerating grids used in the EAST's ion source. Preliminary spectroscopic experimental results are presented comparable to the calorimetrically determined value of theoretical calculation.

  12. THE CONTINUED DEVELOPMENT OF THE SNS EXTERNAL ANTENNA H- ION SOURCE

    Energy Technology Data Exchange (ETDEWEB)

    Welton, Robert F [ORNL; Carmichael, Justin R [ORNL; Desai, Nandishkumar J [ORNL; Fuja, Raymond E [ORNL; Goulding, Richard Howell [ORNL; Han, Baoxi [ORNL; Kang, Yoon W [ORNL; Lee, Shyh-Yuan [ORNL; Murray Jr, S N [ORNL; Pennisi, Terry R [ORNL; Potter, Kerry G [ORNL; Santana, Manuel [ORNL; Stockli, Martin P [ORNL

    2010-01-01

    The U.S. Spallation Neutron Source (SNS) is an accelerator-based, pulsed neutron-scattering facility, currently in the process of ramping up neutron production. In order to insure that the SNS will meet operational commitments as well as provide for future facility upgrades with high reliability, we are developing an RF-driven, H- ion source based on a water-cooled, ceramic aluminum nitride (AlN) plasma chamber. To date, early versions of this source has delivered up to 42 mA to the SNS Front End (FE) and unanalyzed beam currents up to ~ 100mA (60Hz, 1ms) to the ion source test stand. This source was operated on the SNS accelerator from February to April 2009 and produced ~35mA (beam current required by the ramp up plan) with availability of ~97%. During this run several ion source failures identified reliability issues which must be addressed before the source re-enters routine operation: plasma ignition, antenna lifetime, magnet cooling and cooling jacket integrity. This report discusses these issues, details proposed engineering solutions and notes progress to date.

  13. Low pressure and high power rf sources for negative hydrogen ions for fusion applications (ITER neutral beam injection).

    Science.gov (United States)

    Fantz, U; Franzen, P; Kraus, W; Falter, H D; Berger, M; Christ-Koch, S; Fröschle, M; Gutser, R; Heinemann, B; Martens, C; McNeely, P; Riedl, R; Speth, E; Wünderlich, D

    2008-02-01

    The international fusion experiment ITER requires for the plasma heating and current drive a neutral beam injection system based on negative hydrogen ion sources at 0.3 Pa. The ion source must deliver a current of 40 A D(-) for up to 1 h with an accelerated current density of 200 Am/(2) and a ratio of coextracted electrons to ions below 1. The extraction area is 0.2 m(2) from an aperture array with an envelope of 1.5 x 0.6 m(2). A high power rf-driven negative ion source has been successfully developed at the Max-Planck Institute for Plasma Physics (IPP) at three test facilities in parallel. Current densities of 330 and 230 Am/(2) have been achieved for hydrogen and deuterium, respectively, at a pressure of 0.3 Pa and an electron/ion ratio below 1 for a small extraction area (0.007 m(2)) and short pulses (ITER source but without extraction system, is intended to demonstrate the size scaling and plasma homogeneity of rf ion sources. The source operates routinely now. First results on plasma homogeneity obtained from optical emission spectroscopy and Langmuir probes are very promising. Based on the success of the IPP development program, the high power rf-driven negative ion source has been chosen recently for the ITER beam systems in the ITER design review process.

  14. Installation and Debugging of the Axial Injection Line for CYCIAE-100

    Institute of Scientific and Technical Information of China (English)

    YAO; Hong-juan; ZHENG; Xia; MA; Ming-wu; PAN; Gao-feng; ZHANG; Su-ping; WU; Long-cheng; CAI; Hong-ru; GE; Tao

    2012-01-01

    <正>An external multi-cusp ion source and an axial injection line are used in CYCIAE-100 cyclotron for extracting and transporting H- beam. The beam is transported by the injection line and bended by a spiralinflector to the median plane of the machine, and begins to be accelerated by Dee voltage. The total length of the injection line and the ion source is 2 781 mm. The injection line is composed of a big vacuum

  15. Time course of expiratory propofol after bolus injection as measured by ion molecule reaction mass spectrometry.

    Science.gov (United States)

    Hornuss, Cyrill; Wiepcke, Dirk; Praun, Siegfried; Dolch, Michael E; Apfel, Christian C; Schelling, Gustav

    2012-04-01

    Propofol in exhaled breath can be detected and monitored in real time by ion molecule reaction mass spectrometry (IMR-MS). In addition, propofol concentration in exhaled breath is tightly correlated with propofol concentration in plasma. Therefore, real-time monitoring of expiratory propofol could be useful for titrating intravenous anesthesia, but only if concentration changes in plasma can be determined in exhaled breath without significant delay. To evaluate the utility of IMR-MS during non-steady-state conditions, we measured the time course of both expiratory propofol concentration and the processed electroencephalography (EEG) as a surrogate outcome for propofol effect after an IV bolus induction of propofol. Twenty-one patients scheduled for routine surgery were observed after a bolus of 2.5 mg kg(-1) propofol for induction of anesthesia. Expiratory propofol was measured using IMR-MS and the cerebral propofol effect was estimated using the bispectral index (BIS). Primary endpoints were time to detection of expiratory propofol and time to onset of propofol's effect on BIS, and the secondary endpoint was time to peak effect (highest expiratory propofol or lowest BIS). Expiratory propofol and changes in BIS were first detected at 43 ± 21 and 49 ± 11 s after bolus injection, respectively (P = 0.29). Peak propofol concentrations (9.2 ± 2.4 parts-per-billion) and lowest BIS values (23 ± 4) were reached after 208 ± 57 and 219 ± 62 s, respectively (P = 0.57). Expiratory propofol concentrations measured by IMR-MS have similar times to detection and peak concentrations compared with propofol effect as measured by the processed EEG (BIS). This suggests that expiratory propofol concentrations may be useful for titrating intravenous anesthesia.

  16. All-optical clock recovery based on simultaneous external injection-locking and self-seeding of a Fabry-Perot laser diode

    Science.gov (United States)

    Fang, Xiaohui; Wai, Ping Kong A.; Lu, Chao; Tam, Hwa Yaw; Qureshi, Khurram K.

    2011-02-01

    We proposed and demonstrated a novel, simple, and low cost method for all-optical clock recovery based on the switching between two injection-locked longitudinal modes in a dc-biased multi-quantum-well Fabry-Perot laser diode (FP-LD). The dc biased FP-LD is simultaneously injection-locked by a return-to-zero data signal at one of the longitudinal modes of the FP-LD and self-seeded at another longitudinal mode by using a uniform fiber Bragg grating as a feedback component. The powers and detunes of the data signal and self-seeding signal are chosen such that self-seeding is realized in the FP-LD only when data signal power is low. Clock signals of data streams at different data rates can be obtained by tuning the optical delay line in the external self-seeding loop. We have demonstrated all-optical clock recovery at 10 GHz. The pulse width, time-bandwidth product, side mode suppression ration, root mean square timing jitter, and average power of the recovered clock signals are 50 ps, 0.5, 50 dB, 248 fs, and 3.6 dBm, respectively. Clock recovery is possible at wavelength within the gain band of the FP-LD. We also find and explore in the experiment the influence of detune between the external data signal and the nearest FP-LD longitudinal mode to the recovered clock.

  17. Effect of external turbulence on the efficiency of film cooling with coolant injection into a transverse trench

    Science.gov (United States)

    Khalatov, A. A.; Panchenko, N. A.; Severin, S. D.

    2017-09-01

    Film cooling is among the basic methods used for thermal protection of blades in modern high-temperature gas turbines. Results of computer simulation of film cooling with coolant injection via a row of conventional inclined holes or a row of holes in a trench are presented in this paper. The ANSYS CFX 14 commercial software package was used for CFD-modeling. The effect is studied of the mainstream turbulence on the film cooling efficiency for the blowing ratio range between 0.6 and 2.3 and three different turbulence intensities of 1, 5, and 10%. The mainstream velocity was 150 and 400 m/s, while the temperatures of the mainstream and the injected coolant were 1100 and 500°C, respectively. It is demonstrated that, for the coolant injection via one row of trenched holes, an increase in the mainstream turbulence intensity reduces the film cooling efficiency in the entire investigated range of blowing ratios. It was revealed that freestream turbulence had varied effects on the film cooling efficiency depending on the blowing ratio and mainstream velocity in a blade channel. Thus, an increase in the mainstream turbulence intensity from 1 to 10% decreases the surface-averaged film cooling efficiency by 3-10% at a high mainstream velocity (400 m/s) in the blade channel and by 12-23% at a moderate velocity (of 150 m/s). Here, lower film cooling efficiencies correspond to higher blowing ratios. The effect of mainstream turbulence intensity on the film cooling efficiency decreases with increasing the mainstream velocity in the modeled channel for both investigated configurations.

  18. External injection and acceleration of electron bunch in front of the plasma wakefield produced by a periodic chirped laser pulse

    Science.gov (United States)

    Eslami, Esmaeil; Afhami, Saeedeh

    2017-01-01

    Herein, we present the analytical results on the behavior of the electron bunch injected in front of the plasma wakefield produced by a chirped laser pulse. In particular, a periodic chirped pulse may produce an ultra-relativistic electron bunch with a relatively small energy spread. The electrons are trapped near the region of the first accelerating maximum of the wakefield and are compressed in both the longitudinal and transverse directions (betatron oscillation). Our results are in good agreement with the one-dimensional results recently published.

  19. All-Optical envelope detection and fiber transmission of wireless signals by external injection of a DFB laser

    DEFF Research Database (Denmark)

    Prince, Kamau; Tafur Monroy, Idelfonso

    2008-01-01

    We outline a novel method for all-optical envelope detection of wireless signals by exploiting cross-gain modulation effects in a distributed feedback laser operating with optical injection. We successfully demonstrate envelope detection of a 20-GHz carrier amplitude-shift-keying modulated signal...... at 2.5 Gb/s and its transmission over a 70-km optical fiber link. We present results including bit-error-rate measurements, signal waveforms, and receiver sensitivity penalties associated with envelope detection and fiber transmission....

  20. Feasibility of externally activated self-repairing concrete with epoxy injection network and Cu-Al-Mn superelastic alloy reinforcing bars

    Science.gov (United States)

    Pareek, Sanjay; Shrestha, Kshitij C.; Suzuki, Yusuke; Omori, Toshihiro; Kainuma, Ryosuke; Araki, Yoshikazu

    2014-10-01

    This paper studies the effectiveness of an externally activated self-repairing technique for concrete members with epoxy injection network and Cu-Al-Mn superelastic alloy (SEA) reinforcing bars (rebars). Compared to existing crack self-repairing and self-healing techniques, the epoxy injection network has the following strengths: (1) Different from the self-repairing methods using brittle containers or tubes for adhesives, the proposed self-repair process can be performed repeatedly and is feasible for onsite concrete casting. (2) Different from the autogenic self-healing techniques, full strength recovery can be achieved in a shorter time period without the necessity of water. This paper attempts to enhance the self-repairing capability of the epoxy injection network by reducing residual cracks by using cost-effective Cu-based SEA bars. The effectiveness of the present technique is examined using concrete beam specimens reinforced by 3 types of bars. The first specimen is reinforced by steel deformed bars, the second by steel threaded bars, and finally by SEA threaded rebars. The tests were performed with a 3 point cyclic loading with increasing amplitude. From the test results, effective self-repairing was confirmed for small deformation levels irrespective of the reinforcement types. Effective self-repairing was observed in the SEA reinforced specimen even under much larger deformations. Nonlinear finite element analysis was performed to confirm the experimental findings.

  1. The new external ion beam analysis setup at the Demokritos Tandem accelerator and first applications in cultural heritage

    Science.gov (United States)

    Sokaras, Dimosthenis; Bistekos, Euthimios; Georgiou, Lambros; Salomon, Joseph; Bogovac, Mladen; Aloupi-Siotis, Eleni; Paschalis, Vasilis; Aslani, Ioanna; Karabagia, Sofia; Lagoyannis, Anastasios; Harissopulos, Sotirios; Kantarelou, Vasiliki; Karydas, Andreas-Germanos

    2011-03-01

    At the 5.5 MV Tandem VdG accelerator of the Institute of Nuclear Physics of N.C.S.R. "Demokritos", Athens, Greece, an external ion-beam set-up has been recently developed and installed. The aim of this development was to integrate the analytical capabilities of the PIXE, RBS and PIGE ion beam techniques in one experimental set-up, so that to attain a complete elemental and near surface structural characterization of samples in an almost non-destructive way and without any limitation concerning their size or conductive state. A careful 3D mechanical drawing optimized the set-up experimental parameters achieving probe dimensions at the millimeter range (1 mm 2) and fulfilling the special requirements imposed for optimum performance of the aforementioned techniques, including the possibility to use heavier, than protons, ion beams. For the digital pulse processing of the X-ray, γ-ray and charged particle detector signals, novel hardware and software tools were developed based on a custom FPGA configuration. The first applications were focused in the quality control of materials that have been intentionally contaminated with a particular tracer-element ("tagged" materials). The tagged materials which were developed and tested are technologically authentic replicas of ancient attic ceramics with black glazed decoration. Analytical diagnostic studies were carried out for a few representative paintings of contemporary Greek painters in order to identify and document materials/pigments and techniques and eventually to prevent trade of fakes. Finally, ancient glass beads were also examined with respect to the sodium concentration and its in-depth homogeneity.

  2. The new external ion beam analysis setup at the Demokritos Tandem accelerator and first applications in cultural heritage

    Energy Technology Data Exchange (ETDEWEB)

    Sokaras, Dimosthenis, E-mail: dsokaras@inp.demokritos.g [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Bistekos, Euthimios; Georgiou, Lambros [Philon Models, 18541 Piraeus (Greece); Salomon, Joseph [Laboratoire du C2RMF, Centre de Rechereche et de Restauration des Musees du France, 75001 Paris (France); Bogovac, Mladen [Institute Ruder Boskovic, 10002 Zagreb (Croatia); Aloupi-Siotis, Eleni [Thetis Authentics Ltd., 11636 Athens (Greece); Paschalis, Vasilis [Benaki Museum, 10674 Athens (Greece); Aslani, Ioanna [Thetis Authentics Ltd., 11636 Athens (Greece); Karabagia, Sofia; Lagoyannis, Anastasios; Harissopulos, Sotirios; Kantarelou, Vasiliki [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Karydas, Andreas-Germanos [Institute of Nuclear Physics, N.C.S.R. ' Demokritos' , Aghia Paraskevi, 15310 Athens (Greece); Nuclear Spectrometry and Applications Laboratory, International Atomic Energy Agency (IAEA), 2444 Seibersdorf (Austria)

    2011-03-01

    At the 5.5 MV Tandem VdG accelerator of the Institute of Nuclear Physics of N.C.S.R. 'Demokritos', Athens, Greece, an external ion-beam set-up has been recently developed and installed. The aim of this development was to integrate the analytical capabilities of the PIXE, RBS and PIGE ion beam techniques in one experimental set-up, so that to attain a complete elemental and near surface structural characterization of samples in an almost non-destructive way and without any limitation concerning their size or conductive state. A careful 3D mechanical drawing optimized the set-up experimental parameters achieving probe dimensions at the millimeter range (1 mm{sup 2}) and fulfilling the special requirements imposed for optimum performance of the aforementioned techniques, including the possibility to use heavier, than protons, ion beams. For the digital pulse processing of the X-ray, {gamma}-ray and charged particle detector signals, novel hardware and software tools were developed based on a custom FPGA configuration. The first applications were focused in the quality control of materials that have been intentionally contaminated with a particular tracer-element ('tagged' materials). The tagged materials which were developed and tested are technologically authentic replicas of ancient attic ceramics with black glazed decoration. Analytical diagnostic studies were carried out for a few representative paintings of contemporary Greek painters in order to identify and document materials/pigments and techniques and eventually to prevent trade of fakes. Finally, ancient glass beads were also examined with respect to the sodium concentration and its in-depth homogeneity.

  3. External Second Gate, Fourier Transform Ion Mobility Spectrometry: Parametric Optimization for Detection of Weapons of Mass Destruction

    Directory of Open Access Journals (Sweden)

    Edward E. Tarver

    2004-03-01

    Full Text Available Abstract: Ion mobility spectrometry (IMS is recognized as one of the most sensitive and robust techniques for the detection of narcotics, explosives and chemical warfare agents. IMS is widely used in forensic, military and security applications. Increasing threat of terrorist attacks, the proliferation of narcotics, Chemical Weapons Convention (CWC treaty verification as well as humanitarian de-mining efforts have mandated that equal importance be placed on the time required to obtain results as well as the quality of the analytical data. [1] In this regard IMS is virtually unrivaled when both speed of response and sensitivity have to be considered. [2] The problem with conventional (signal averaging IMS systems is the fixed duty cycle of the entrance gate that restricts to less than 1%, the number of available ions contributing to the measured signal. Furthermore, the signal averaging process incorporates scan-to-scan variations that degrade the spectral resolution contributing to misidentifications and false positives. With external second gate, Fourier Transform ion mobility spectrometry (FT-IMS the entrance gate frequency is variable and can be altered in conjunction with other data acquisition parameters (scan time and sampling rate to increase the spectral resolution to reduce false alarms and improve the sensitivity for early warning and contamination avoidance. In addition, with FT-IMS the entrance gate operates with a 50% duty cycle and so affords a seven-fold increase in sensitivity. Recent data on high explosives are presented to demonstrate the parametric optimization in sensitivity and resolution of our system.

  4. Development of heating device / development of the high current ion source for neutral beam injection

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Heon Ju; Lee, Dong Gyu; Lee, Kyong Jin; Ko Tae Kyong [Cheju National Univ., Cheju (Korea)

    1998-08-01

    The design and fabrication of a high current ion source for NBI was carried out. The scale of an ion source was reduced for mock-up test. To develop the high current ion source with the high operational stability and the long lifetime, the parameters including an arc current, gas pressure and extraction voltage should be optimized. If fabricated ion source would be tested, its parameters could be optimized experimentally. Through the optimization of the ion source parameter, the core technology for NBI is established and the experiment of current drive in the fusion device can be performed. This technology also can be applied to the ion beam technology in the field of new material synthesis and semiconductor industry. 24 refs., 22 figs., 13 tabs. (Author)

  5. Magnetic latitude dependence of oxygen charge states in the global magnetosphere: Insights into solar wind-originating ion injection

    Science.gov (United States)

    Allen, R. C.; Livi, S. A.; Vines, S. K.; Goldstein, J.

    2016-10-01

    Understanding the sources and subsequent evolution of plasma in a magnetosphere holds intrinsic importance for magnetospheric dynamics. Previous studies have investigated the balance of ionospheric-originating heavy ions (low charge state) from those of solar wind origin (high charge state) in the magnetosphere of Earth. These studies have suggested a variety of entry mechanisms for solar wind ions to penetrate into the magnetosphere. Following from recently published distributions for oxygen charge states observed by the Polar spacecraft, this paper investigates oxygen charge state flux distributions versus L shell and magnetic latitude. By showing these distributions in this frame, and binning by various proxies for magnetospheric dynamics (Dst, AE, VSW∗BZ, Pdyn), insight has been gained into the underlying physics at play for oxygen injection. Ionospheric-originating oxygen is observed to depend predominantly on Dst, whereas solar wind-originating oxygen is observed to have a strong dependence on solar wind dynamic pressure (Pdyn) at the flanks and on VSW∗BZ at the dayside. This suggests that both Kelvin-Helmholtz instabilities and reconnection play major roles in solar wind ion penetration into a magnetosphere. Additionally, the near-Earth magnetotail reconnection site does not seem to be a major injection site of solar wind-originating plasma in the 1 to 200 keV/e energy range.

  6. Work function measurements during plasma exposition at conditions relevant in negative ion sources for the ITER neutral beam injection.

    Science.gov (United States)

    Gutser, R; Wimmer, C; Fantz, U

    2011-02-01

    Cesium seeded sources for surface generated negative hydrogen ions are major components of neutral beam injection systems in future large-scale fusion experiments such as ITER. The stability and delivered current density depend highly on the work function during vacuum and plasma phases of the ion source. One of the most important quantities that affect the source performance is the work function. A modified photocurrent method was developed to measure the temporal behavior of the work function during and after cesium evaporation. The investigation of cesium exposed Mo and MoLa samples under ITER negative hydrogen ion based neutral beam injection relevant surface and plasma conditions showed the influence of impurities which result in a fast degradation when the plasma exposure or the cesium flux onto the sample is stopped. A minimum work function close to that of bulk cesium was obtained under the influence of the plasma exposition, while a significantly higher work function was observed under ITER-like vacuum conditions.

  7. Injection and extraction computer control system HIRFL-SSC The HIRFL-SSC is stated for Heavy Ion Research Facility of Lanzhou-Separated Sector Cyclotron

    CERN Document Server

    Zhang Wei; Chen Yun; Zhang Xia; Hu Jian Jun; Xu Xing Ming

    2002-01-01

    The injection and extraction computer control system of HIRFL-SSC (Heavy Ion Research Facility of Lanzhou-Separated Sector Cyclotron) have been introduced. Software is described briefly. Hardware structure is mainly presented. The computer control system realize that the adjustment of injection and extraction can done by PC and operate interface is Windows style. The system can make the adjustment convenient and veracious

  8. Comparative analysis of frequency and noise characteristics of Fabry – Perot and distributed feedback laser diodes with external optical injection locking

    Energy Technology Data Exchange (ETDEWEB)

    Afonenko, A A; Dorogush, E S [Belarusian State University, Minsk (Belarus); Malyshev, S A; Chizh, A L [B.I. Stepanov Institute of Physics, National Academy of Sciences of Belarus, Minsk (Belarus)

    2015-11-30

    Using a system of coupled travelling wave equations, in the small-signal regime we analyse frequency and noise characteristics of index- or absorption-coupled distributed feedback laser diodes, as well as of Fabry – Perot (FP) laser diodes. It is shown that the weakest dependence of the direct modulation efficiency on the locking frequency in the regime of strong external optical injection locking is exhibited by a FP laser diode formed by highly reflective and antireflective coatings on the end faces of a laser structure. A reduction in the dependence of output characteristics of the laser diode on the locking frequency can be attained by decreasing the reflection coefficient of the antireflective FP mirror. (control of laser radiation parameters)

  9. On the meniscus formation and the negative hydrogen ion extraction from ITER neutral beam injection relevant ion source

    Science.gov (United States)

    Mochalskyy, S.; Wünderlich, D.; Ruf, B.; Fantz, U.; Franzen, P.; Minea, T.

    2014-10-01

    The development of a large area (Asource,ITER = 0.9 × 2 m2) hydrogen negative ion (NI) source constitutes a crucial step in construction of the neutral beam injectors of the international fusion reactor ITER. To understand the plasma behaviour in the boundary layer close to the extraction system the 3D PIC MCC code ONIX is exploited. Direct cross checked analysis of the simulation and experimental results from the ITER-relevant BATMAN source testbed with a smaller area (Asource,BATMAN ≈ 0.32 × 0.59 m2) has been conducted for a low perveance beam, but for a full set of plasma parameters available. ONIX has been partially benchmarked by comparison to the results obtained using the commercial particle tracing code for positive ion extraction KOBRA3D. Very good agreement has been found in terms of meniscus position and its shape for simulations of different plasma densities. The influence of the initial plasma composition on the final meniscus structure was then investigated for NIs. As expected from the Child-Langmuir law, the results show that not only does the extraction potential play a crucial role on the meniscus formation, but also the initial plasma density and its electronegativity. For the given parameters, the calculated meniscus locates a few mm downstream of the plasma grid aperture provoking a direct NI extraction. Most of the surface produced NIs do not reach the plasma bulk, but move directly towards the extraction grid guided by the extraction field. Even for artificially increased electronegativity of the bulk plasma the extracted NI current from this region is low. This observation indicates a high relevance of the direct NI extraction. These calculations show that the extracted NI current from the bulk region is low even if a complete ion-ion plasma is assumed, meaning that direct extraction from surface produced ions should be present in order to obtain sufficiently high extracted NI current density. The calculated extracted currents, both ions

  10. Fast ion confinement and stability in a neutral beam injected reversed field pinch

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, J. K.; Almagri, A. F.; Den Hartog, D. J.; Eilerman, S.; Forest, C. B.; Koliner, J. J.; Mirnov, V. V.; Morton, L. A.; Nornberg, M. D.; Parke, E.; Reusch, J. A.; Sarff, J. S.; Waksman, J. [University of Wisconsin, Madison, Wisconsin 53706 (United States); Belykh, V.; Davydenko, V. I.; Ivanov, A. A.; Polosatkin, S. V.; Tsidulko, Y. A. [Budker Institute of Nuclear Physics, Novosibirsk (Russian Federation); Lin, L. [University of California, Los Angeles, California 90095 (United States); Liu, D. [University of California, Irvine, California 92697 (United States); and others

    2013-05-15

    The behavior of energetic ions is fundamentally important in the study of fusion plasmas. While well-studied in tokamak, spherical torus, and stellarator plasmas, relatively little is known in reversed field pinch plasmas about the dynamics of fast ions and the effects they cause as a large population. These studies are now underway in the Madison Symmetric Torus with an intense 25 keV, 1 MW hydrogen neutral beam injector (NBI). Measurements of the time-resolved fast ion distribution via a high energy neutral particle analyzer, as well as beam-target neutron flux (when NBI fuel is doped with 3–5% D{sub 2}) both demonstrate that at low concentration the fast ion population is consistent with classical slowing of the fast ions, negligible cross-field transport, and charge exchange as the dominant ion loss mechanism. A significant population of fast ions develops; simulations predict a super-Alfvénic ion density of up to 25% of the electron density with both a significant velocity space gradient and a sharp radial density gradient. There are several effects on the background plasma including enhanced toroidal rotation, electron heating, and an altered current density profile. The abundant fast particles affect the plasma stability. Fast ions at the island of the core-most resonant tearing mode have a stabilizing effect, and up to 60% reduction in the magnetic fluctuation amplitude is observed during NBI. The sharp reduction in amplitude, however, has little effect on the underlying magnetic island structure. Simultaneously, beam driven instabilities are observed as repetitive ∼50 μs bursts which coincide with fast particle redistribution; data indicate a saturated core fast ion density well below purely classical predictions.

  11. An isocratic ion exchange HPLC method for the simultaneous determination of flucloxacillin and amoxicillin in a pharmaceutical formulation for injection.

    Science.gov (United States)

    Liu, Hao; Wang, Hongwu; Sunderland, V Bruce

    2005-02-23

    An isocratic ion exchange high performance liquid chromatography method was developed for the simultaneous determination of flucloxacillin and amoxicillin in pharmaceutical formulations for injections. The separation was made by a ZORBAX 300-SCX column using 0.025 M ammonium dihydrogen phosphate (adjusted to pH 2.6 with phosphoric acid)-acetonitrile (95:5) as mobile phase. The validation of the method was performed, and specificity, reproducibility, precision and accuracy were confirmed. The limits of quantification were approximately 0.2 microg/ml for each drug. Due to its simplicity and accuracy the method is particularly suitable for routine pharmaceutical quality control.

  12. On the dynamics of Cu ions injection into low-k nanoporous materials under oscillating applied fields

    Science.gov (United States)

    Borja, Juan; Plawsky, Joel. L.; Lu, T.-M.; Gill, William N.

    2013-01-01

    Cu injection into low-k dielectrics was studied using oscillating bipolar field experiments coupled with a mass transport model. Cu/SiCOH/Si structures were stressed using an oscillating square bipolar applied field at 200 °C. Breakdown was defined experimentally as the time it takes for the leakage current to exceed 1 × 10-5 A under given stress conditions. Time to failure was found to depend on field oscillating frequency and amplitude of the applied field. It was determined that ion solubility primarily affects the magnitude of lifetime enhancement, while mobility affects its onset in the frequency domain. Overtime, the local field generated by the accumulation of Cu ions during bias temperature stress resists the action of the oscillating field thus inhibiting the ability to sweep ions from cathode to anode through reversal of the applied field and thereby limits the observed lifetime enhancement. Predictions from the model match trends for experimental data involving transport of Cu ions into SiCOH.

  13. Charge Breeding of Radioactive Ions

    CERN Document Server

    Wenander, F J C

    2013-01-01

    Charge breeding is a technique to increase the charge state of ions, in many cases radioactive ions. The singly charged radioactive ions, produced in an isotope separator on-line facility, and extracted with a low kinetic energy of some tens of keV, are injected into a charge breeder, where the charge state is increased to Q. The transformed ions are either directed towards a dedicated experiment requiring highly charged ions, or post-accelerated to higher beam energies. In this paper the physics processes involved in the production of highly charged ions will be introduced, and the injection and extraction beam parameters of the charge breeder defined. A description of the three main charge-breeding methods is given, namely: electron stripping in gas jet or foil; external ion injection into an electron-beam ion source/trap (EBIS/T); and external ion injection into an electron cyclotron resonance ion source (ECRIS). In addition, some preparatory devices for charge breeding and practical beam delivery aspects ...

  14. Particle simulation of collision dynamics for ion beam injection into a rarefied gas

    Energy Technology Data Exchange (ETDEWEB)

    Giuliano, Paul N.; Boyd, Iain D. [Department of Aerospace Engineering, University of Michigan, Ann Arbor, Michigan 48109 (United States)

    2013-03-15

    This study details a comparison of ion beam simulations with experimental data from a simplified plasma test cell in order to study and validate numerical models and environments representative of electric propulsion devices and their plumes. The simulations employ a combination of the direct simulation Monte Carlo and particle-in-cell methods representing xenon ions and atoms as macroparticles. An anisotropic collision model is implemented for momentum exchange and charge exchange interactions between atoms and ions in order to validate the post-collision scattering behaviors of dominant collision mechanisms. Cases are simulated in which the environment is either collisionless or non-electrostatic in order to prove that the collision models are the dominant source of low- and high-angle particle scattering and current collection within this environment. Additionally, isotropic cases are run in order to show the importance of anisotropy in these collision models. An analysis of beam divergence leads to better characterization of the ion beam, a parameter that requires careful analysis. Finally, suggestions based on numerical results are made to help guide the experimental design in order to better characterize the ion environment.

  15. Flow-injection sample preconcentration for ion-pair chromatography of trace metals in waters.

    Science.gov (United States)

    Pobozy, Ewa; Halko, Radoslav; Krasowski, Marcin; Wierzbicki, Tomasz; Trojanowicz, Marek

    2003-05-01

    Selected trace transition metal ions have been determined in an FIA/HPLC hyphenated system using on-line preconcentration on cellulose functionalised sorbent Cellex P. For HPLC separation ion-pair chromatography was employed with spectrophotometric detection at 510 nm using post-column derivatisation with PAR. Favourable kinetic conditions of sorption and elution as well as optimisation of hyphenated system allowed to obtain detection limits at sub-microgL(-1) level at 25 min preconcentration time. The developed method was employed for determination of Co(II), Ni(II), Cd(II) and Mn(II) in river water with reasonable agreement of obtained results with electrothermal AAS determination.

  16. Collisionless Electron-ion Shocks in Relativistic Unmagnetized Jet-ambient Interactions: Non-thermal Electron Injection by Double Layer

    Science.gov (United States)

    Ardaneh, Kazem; Cai, Dongsheng; Nishikawa, Ken-Ichi

    2016-08-01

    The course of non-thermal electron ejection in relativistic unmagnetized electron-ion shocks is investigated by performing self-consistent particle-in-cell simulations. The shocks are excited through the injection of a relativistic jet into ambient plasma, leading to two distinct shocks (referred to as the trailing shock and leading shock) and a contact discontinuity. The Weibel-like instabilities heat the electrons up to approximately half of the ion kinetic energy. The double layers formed in the trailing and leading edges then accelerate the electrons up to the ion kinetic energy. The electron distribution function in the leading edge shows a clear, non-thermal power-law tail which contains ˜1% of electrons and ˜8% of the electron energy. Its power-law index is -2.6. The acceleration efficiency is ˜23% by number and ˜50% by energy, and the power-law index is -1.8 for the electron distribution function in the trailing edge. The effect of the dimensionality is examined by comparing the results of three-dimensional simulations with those of two-dimensional simulations. The comparison demonstrates that electron acceleration is more efficient in two dimensions.

  17. Collisionless electron-ion shocks in relativistic unmagnetized jet-ambient interactions: Non-thermal electron injection by double layer

    CERN Document Server

    Ardaneh, Kazem; Nishikawa, Ken-Ichi

    2016-01-01

    The course of non-thermal electron ejection in relativistic unmagnetized electron-ion shocks is investigated by performing self-consistent particle-in-cell simulations. The shocks are excited through the injection of relativistic jet into ambient plasma, leading to two distinct shocks (named as the trailing shock and leading shock) and a contact discontinuity. The Weibel-like instabilities heat the electrons up to approximately half of ion kinetic energy. The double layers formed in the trailing and leading edges then accelerated the electrons by the ion kinetic energy. The electron distribution function in the leading edge shows a clear non-thermal power-law tail which contains $\\sim1\\%$ of electrons and $\\sim8\\%$ of electron energy. Its power-law index is -2.6. The acceleration efficiency is $\\sim23\\%$ by number and $\\sim50\\%$ by energy and the power-law index is -1.8 for electron distribution function in the trailing edge. The effect of the dimensionality is examined by comparing results of 3D simulation w...

  18. Combination of External Beam Radiotherapy (EBRT) With Intratumoral Injection of Dendritic Cells as Neo-Adjuvant Treatment of High-Risk Soft Tissue Sarcoma Patients

    Energy Technology Data Exchange (ETDEWEB)

    Finkelstein, Steven E., E-mail: steven.finkelstein@moffitt.org [H. Lee Moffitt Cancer Center, Tampa, FL (United States); Iclozan, Cristina; Bui, Marilyn M.; Cotter, Matthew J.; Ramakrishnan, Rupal; Ahmed, Jamil; Noyes, David R.; Cheong, David; Gonzalez, Ricardo J.; Heysek, Randy V.; Berman, Claudia; Lenox, Brianna C.; Janssen, William; Zager, Jonathan S.; Sondak, Vernon K.; Letson, G. Douglas; Antonia, Scott J. [H. Lee Moffitt Cancer Center, Tampa, FL (United States); Gabrilovich, Dmitry I., E-mail: dmitry.gabrilovich@moffitt.org [H. Lee Moffitt Cancer Center, Tampa, FL (United States)

    2012-02-01

    Purpose: The goal of this study was to determine the effect of combination of intratumoral administration of dendritic cells (DC) and fractionated external beam radiation (EBRT) on tumor-specific immune responses in patients with soft-tissue sarcoma (STS). Methods and Material: Seventeen patients with large (>5 cm) high-grade STS were enrolled in the study. They were treated in the neoadjuvant setting with 5,040 cGy of EBRT, split into 28 fractions and delivered 5 days per week, combined with intratumoral injection of 10{sup 7} DCs followed by complete resection. DCs were injected on the second, third, and fourth Friday of the treatment cycle. Clinical evaluation and immunological assessments were performed. Results: The treatment was well tolerated. No patient had tumor-specific immune responses before combined EBRT/DC therapy; 9 patients (52.9%) developed tumor-specific immune responses, which lasted from 11 to 42 weeks. Twelve of 17 patients (70.6%) were progression free after 1 year. Treatment caused a dramatic accumulation of T cells in the tumor. The presence of CD4{sup +} T cells in the tumor positively correlated with tumor-specific immune responses that developed following combined therapy. Accumulation of myeloid-derived suppressor cells but not regulatory T cells negatively correlated with the development of tumor-specific immune responses. Experiments with {sup 111}In labeled DCs demonstrated that these antigen presenting cells need at least 48 h to start migrating from tumor site. Conclusions: Combination of intratumoral DC administration with EBRT was safe and resulted in induction of antitumor immune responses. This suggests that this therapy is promising and needs further testing in clinical trials design to assess clinical efficacy.

  19. Laser Produced Ions as an Injection Beam for Cancer Therapy Facility

    CERN Document Server

    Noda, A; Iwashita, Y; Nakamura, S; Sakabe, S; Shimizu, S; Shirai, T; Tongu, H

    2004-01-01

    Ion production from a solid target by a high-power short pulse laser has been investigated to replace the injector linac of the synchrotron dedicated for cancer therapy. As the high power laser, the laser with the peak power of 100 TW and minimum pulse duration of 20 fs which has been developed at JAERI Kansai Research Establishment, is assumed. Laser produced ions with 100% energy spread is energy selected within ±5% and then phase rotated with use of the RF electric field synchronized to the pulse laser, which further reduces the energy spread to ±1%. The scheme of the phase rotation is presented together with the experimental results of laser production from the thin foil target.

  20. Heavy Inertial Confinement Energy: Interactions Involoving Low charge State Heavy Ion Injection Beams

    Energy Technology Data Exchange (ETDEWEB)

    DuBois, Robert D

    2006-04-14

    During the contract period, absolute cross sections for projectile ionization, and in some cases for target ionization, were measured for energetic (MeV/u) low-charge-state heavy ions interacting with gases typically found in high and ultra-high vacuum environments. This information is of interest to high-energy-density research projects as inelastic interactions with background gases can lead to serious detrimental effects when intense ion beams are accelerated to high energies, transported and possibly confined in storage rings. Thus this research impacts research and design parameters associated with projects such as the Heavy Ion Fusion Project, the High Current and Integrated Beam Experiments in the USA and the accelerator upgrade at GSI-Darmstadt, Germany. Via collaborative studies performed at GSI-Darmstadt, at the University of East Carolina, and Texas A&M University, absolute cross sections were measured for a series of collision systems using MeV/u heavy ions possessing most, or nearly all, of their bound electrons, e.g., 1.4 MeV/u Ar{sup +}, Xe{sup 3+}, and U{sup 4,6,10+}. Interactions involving such low-charge-state heavy ions at such high energies had never been previously explored. Using these, and data taken from the literature, an empirical model was developed for extrapolation to much higher energies. In order to extend our measurements to much higher energies, the gas target at the Experimental Storage Ring in GSI-Darmstadt was used. Cross sections were measured between 20 and 50 MeV/u for U{sup 28+}- H{sub 2} and - N{sub 2}, the primary components found in high and ultra-high vacuum systems. Storage lifetime measurements, information inversely proportional to the cross section, were performed up to 180 MeV/u. The lifetime and cross section data test various theoretical approaches used to calculate cross sections for many-electron systems. Various high energy density research projects directly benefit by this information. As a result, the general

  1. Li-ion battery thermal runaway suppression system using microchannel coolers and refrigerant injections

    Science.gov (United States)

    Bandhauer, Todd M.; Farmer, Joseph C.

    2016-11-08

    A battery management system with thermally integrated fire suppression includes a multiplicity of individual battery cells in a housing; a multiplicity of cooling passages in the housing within or between the multiplicity of individual battery cells; a multiplicity of sensors operably connected to the individual battery cells, the sensors adapted to detect a thermal runaway event related to one or more of the multiplicity of individual battery cells; and a management system adapted to inject coolant into at least one of the multiplicity of cooling passages upon the detection of the thermal runaway event by the any one of the multiplicity of sensors, so that the thermal runaway event is rapidly quenched.

  2. Li-ion battery thermal runaway suppression system using microchannel coolers and refrigerant injections

    Energy Technology Data Exchange (ETDEWEB)

    Bandhauer, Todd M.; Farmer, Joseph C.

    2016-11-08

    A battery management system with thermally integrated fire suppression includes a multiplicity of individual battery cells in a housing; a multiplicity of cooling passages in the housing within or between the multiplicity of individual battery cells; a multiplicity of sensors operably connected to the individual battery cells, the sensors adapted to detect a thermal runaway event related to one or more of the multiplicity of individual battery cells; and a management system adapted to inject coolant into at least one of the multiplicity of cooling passages upon the detection of the thermal runaway event by the any one of the multiplicity of sensors, so that the thermal runaway event is rapidly quenched.

  3. Effects of composition and helium injection on dislocation loop development in pure FeNiCr alloys under Ni ion irradiation

    Science.gov (United States)

    Kimoto, Takayoshi

    1993-08-01

    Pure Fe35Ni7Cr, Fe45Ni7Cr, Fe40Ni13Cr and Fe45Ni15Cr alloys were irradiated by 4MeV Ni 2+ ions at 948 K to doses of about 0.05, 0.3 and 1.0 dpa without helium injection or with simultaneous helium injection. With increasing Ni content and decreasing Cr content, the diameter of radiation-induced dislocation loops increased, and the dose at which the dislocation loops disappeared to develop into dislocation networks decreased. The diameter of dislocation loops induced by Ni 2+ ions irradiation with simultaneous helium injection was larger than that without helium injection for the Fe35Ni7Cr and Fe45Ni7Cr alloys.

  4. Development of ion source with a washer gun for pulsed neutral beam injection.

    Science.gov (United States)

    Asai, T; Yamaguchi, N; Kajiya, H; Takahashi, T; Imanaka, H; Takase, Y; Ono, Y; Sato, K N

    2008-06-01

    A new type of economical neutral beam source has been developed by using a single washer gun, pulsed operation, and a simple electrode system. We replaced the conventional hot filaments for arc-discharge-type plasma formation with a single stainless-steel washer gun, eliminating the entire dc power supply for the filaments and the cooling system for the electrodes. Our initial experiments revealed successful beam extraction up to 10 kV and 8.6 A, based on spatial profile measurements of density and temperature in the plasma source. The system also shows the potential to control the beam profile by controlling the plasma parameters in the ion accumulation chamber.

  5. High quality ion channels recordings on an injection molded polymer chip

    DEFF Research Database (Denmark)

    Tanzi, Simone

    , or in recent years using consumable microfluidic chips of high costs. The patch clamping method is widely used both in fundamental studies of electrophysiology of living cells and tissue and in drug discovery. The findings of this work will allow direct recordings of ion channel activity to be made using...... to form high resistance seals in the GOhm range, the so called gigaseals, is demonstrated with a success rate of 15%. The devices were functionally tested with Human Embryonice Kidney (HEK) cells expressing voltage-gated sodium channels and benchmarked against a commercial state-of-the-art system...

  6. Experiments on current-driven three-dimensional ion sound turbulence. I - Return-current limited electron beam injection. II - Wave dynamics

    Science.gov (United States)

    Stenzel, R. L.

    1978-01-01

    Pulsed electron beam injection into a weakly collisional magnetized background plasma is investigated experimentally; properties of the electron beam and background plasma, as well as the low-frequency instabilities and wave dynamics, are discussed. The current of the injected beam closes via a field-aligned return current of background electrons. Through study of the frequency and wavenumber distribution, together with the electron distribution function, the low-frequency instabilities associated with the pulsed injection are identified as ion acoustic waves driven unstable by the return current. The frequency cut-off of the instabilities predicted from renormalized plasma turbulence theory, has been verified experimentally.

  7. Online spectrophotometric determination of Fe(II) and Fe(III) by flow injection combined with low pressure ion chromatography

    Science.gov (United States)

    Chen, Shujuan; Li, Nan; Zhang, Xinshen; Yang, Dongjing; Jiang, Heimei

    2015-03-01

    A simple and new low pressure ion chromatography combined with flow injection spectrophotometric procedure for determining Fe(II) and Fe(III) was established. It is based on the selective adsorption of low pressure ion chromatography column to Fe(II) and Fe(III), the online reduction reaction of Fe(III) and the reaction of Fe(II) in sodium acetate with phenanthroline, resulting in an intense orange complex with a suitable absorption at 515 nm. Various chemical (such as the concentration of colour reagent, eluant and reductive agent) and instrumental parameters (reaction coil length, reductive coil length and wavelength) were studied and were optimized. Under the optimum conditions calibration graph of Fe(II)/Fe(III) was linear in the Fe(II)/Fe(III) range of 0.040-1.0 mg/L. The detection limit of Fe(III) and Fe(II) was respectively 3.09 and 1.55 μg/L, the relative standard deviation (n = 10) of Fe(II) and Fe(III) 1.89% and 1.90% for 0.5 mg/L of Fe(II) and Fe(III) respectively. About 2.5 samples in 1 h can be analyzed. The interfering effects of various chemical species were studied. The method was successfully applied in the determination of water samples.

  8. Ion-selective electrodes for potentiometric determination of ranitidine hydrochloride, applying batch and flow injection analysis techniques.

    Science.gov (United States)

    Issa, Yousry M; Badawy, Sayed S; Mutair, Ali A

    2005-12-01

    New ranitidine hydrochloride (RaCl)-selective electrodes of the conventional polymer membrane type are described. They are based on incorporation of ranitidine-tetraphenylborate (Ra-TPB) ion-pair or ranitidine-phosphotungstate (RaPT) ion-associate in a poly(vinyl chloride) (PVC) membrane plasticized with dioctylphthalate (DOP) or dibutylphthalate (DBP). The electrodes are fully characterized in terms of the membrane composition, solution temperature, and pH. The sensors showed fast and stable responses. Nernstian response was found over the concentration range of 2.0 x 10(-5) M to 1.0 x 10(-2) M and 1.0 x 10(-5) M to 1.0 x 10(-2) M in the case of Ra-TPB electrode and over the range of 1.03 x 10(-5) M to 1.00 x 10(-2) M and 1.0 x 10(-5) M to 1.0 x 10(-2) M in the case of Ra-PT electrode for batch and FIA systems, respectively. The electrodes exhibit good selectivity for RaCl with respect to a large number of common ions, sugars, amino acids, and components other than ranitidine hydrochloride of the investigated mixed drugs. The electrodes have been applied to the potentiometric determination of RaCl in pure solutions and in pharmaceutical preparations under batch and flow injection conditions with a lower detection limit of 1.26 x 10(-5) M and 5.62 x 10(-6) M at 25 +/- 1 degrees C. An average recovery of 100.91% and 100.42% with a relative standard deviation of 0.72% and 0.53% has been achieved.

  9. Magnetospheric effects of ion and atom injections by the satellite power system

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, Y.T.; Luhmann, J.G.; Schulz, M.; Cornwall, J.M.

    1980-07-01

    This is the final report of a two-year assessment of magnetospheric effects of the construction and operation of a satellite power system. This assessment effort is based on application of present scientific knowledge rather than on original scientific research. As such, it appears that mass and energy injections of the system are sufficient to modify the magnetosphere substantially, to the extent of possibly requiring mitigation measures for space systems but not to the extent of causing major redirection of efforts and concepts. The scale of the SPS is so unprecedentedly large, however, that these impressions require verification (or rejection) by in-depth assessment based on original scientific treatment of the principal issues. Indeed, it is perhaps appropriate to state that present ignorance far exceeds present knowledge in regard to SPS magnetospheric effects, even though we only seek to define the approximate limits of magnetospheric modifications here. Modifications of the space radiation environment, of the atmospheric airglow background, of the auroral response to solar activity and of the fluctuations in space plasma density are identified to be the principal impacts.

  10. Study on the luminescence behavior of lanthanide ions with luminol by flow injection chemiluminescence analysis

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Xiaoqing [College of Chemistry and Material Science, Northwest University, 710069 Xi' an (China); Wang, Zhuming [College of Earth Sciences and Land Resources, Chang' an University, 710054 Xi' an (China); Li, Yajuan [College of Chemistry and Material Science, Northwest University, 710069 Xi' an (China); Zhang, Yun [Department of pharmacy, Xi' an Medical University, 710021 Xi' an (China); Guo, Jie; Zhao, Jingchan [College of Chemistry and Material Science, Northwest University, 710069 Xi' an (China); Song, Zhenghua, E-mail: songzhenghua@hotmail.com [College of Chemistry and Material Science, Northwest University, 710069 Xi' an (China)

    2015-06-15

    This work first described the linear quenching of Ln{sup III} (including La{sup III}, Ce{sup III}, Pr{sup III}, Nd{sup III}, Sm{sup III}, Eu{sup III}, Gd{sup III}, Tb{sup III}, Dy{sup III}, Ho{sup III}, Er{sup III}, Tm{sup III}, Yb{sup III} and Lu{sup III}) on luminol–dissolved oxygen chemiluminescence system and possible quenching mechanism by flow injection analysis. The general equation of the decrement of CL intensity with Ln{sup III} concentration, ΔI=AlnC{sub Ln}+B, was given and the interaction model of Ln{sup III} with luminol, lg[(I{sub 0}−I)/I]=rlg[Ln]+lgK, was established. The sensitive factor A was found to be linear with the physical parameters (Z, γ{sub ±}, E{sup o} and ΔH{sub hyd}). By plotting A against Z, it could be seen light lanthanides (LL) and heavy lanthanides (HL) presented a good symmetry. The results showed that the reaction of Ln{sup III} with luminol was a spontaneous process by the electrostatic force with the association constants K at 10{sup 6}–10{sup 7} level. The binding constants K{sub D} (about 10{sup 4}–10{sup 5}) and the number of binding sites n (about 1) of Ln{sup III} (La{sup III}, Eu{sup III}, Gd{sup III}, Tb{sup III} and Lu{sup III}) to bovine serum albumin were first given by FI–CL, and the binding ability of Ln{sup III} followed the pattern: La{sup III}

  11. Determination of trace metals in seawater by an automated flow injection ion chromatograph pretreatment system with ICPMS.

    Science.gov (United States)

    Ho, Tung-Yuan; Chien, Chia-Te; Wang, Bing-Nan; Siriraks, Archava

    2010-09-15

    A novel flow injection ion chromatograph (FI-IC) system has been developed to fully automate pretreatment procedures for multi-elemental analysis of trace metals in seawater by inductively coupled plasma mass spectrometer (ICPMS). By combining 10-port, 2 position and 3-way valves in the FI-IC manifold, the system effectively increase sample throughput by simultaneously processing three seawater samples online for: sample loading, injection, buffering, preconcentration, matrix removal, metal elution, and sample collection. Forty-two seawater samples can be continuously processed without any manual handing. Each sample pretreatment takes about 10 min by consuming 25 mL of seawater and producing 5 mL of processed concentrated samples for multi-elemental offline analysis by ICPMS. The offline analysis improve analytical precision and significantly increase total numbers of isotopes determined by ICPMS, which include the metals Al, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, Ti, V, and Zn. The blank value and detection limits of trace metals using the system with ICPMS analysis all range from 0.1 to 10 parts per trillion (ppt), except Al, Fe, and Zn. The accuracy of the pretreatment system was validated by measuring open-ocean and coastal reference seawater, NASS-5 and CASS-4. Using the system with ICPMS analysis, we have obtained reliable trace metal concentrations in the water columns of the South China Sea. Possessing the features of full automation, high throughput, low blank, and low reagent volume used, the system automates and simplifies rigorous and complicated pretreatment procedures for multi-elemental analysis of trace metals in seawater and effectively enhances analytical capacity for trace metal analysis in environmental and seawater samples.

  12. Unambiguous identification and discovery of bacterial siderophores by direct injection 21 Tesla Fourier transform ion cyclotron resonance mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Walker, Lawrence R.; Tfaily, Malak M.; Shaw, Jared B.; Hess, Nancy J.; Pasa Tolic, Ljiljana; Koppenaal, David W.

    2017-01-01

    Under iron-limiting conditions, bacteria produce low molecular mass Fe(III) binding molecules known as siderophores to sequester the Fe(III), along with other elements, increasing their bioavailibility. Siderophores are thought to influence iron cycling and biogeochemistry in both marine and terrestrial ecosystems and hence the need for rapid, confident characterization of these compounds has increased. In this study, the type of siderophores produced by two marine bacterial species, Synechococcus sp. PCC 7002 and Vibrio cyclitrophicus 1F53, were characterized using a newly developed 21T Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (FTICR MS) with direct injection electrospray ionization. This technique allowed for the rapid detection of synechobactins from Synechococcus sp. PCC 7002 as well as amphibactins from Vibrio cyclitrophicus 1F53 based on high mass accuracy and resolution allowing for observation of specific Fe isotopic peaks and fine isotopic structure enables highly confident identification of these sideropohores. When combined with molecular network analysis two new amphibactins were discovered and verified by tandem MS. These results show that high-field FTICR MS is a powerful technique that will greatly improve the ability to rapidly identify and discover metal binding species in the environment.

  13. Single column comprehensive analysis of pharmaceutical preparations using dual-injection mixed-mode (ion-exchange and reversed-phase) and hydrophilic interaction liquid chromatography.

    Science.gov (United States)

    Kazarian, Artaches A; Taylor, Mark R; Haddad, Paul R; Nesterenko, Pavel N; Paull, Brett

    2013-12-01

    The comprehensive separation and detection of hydrophobic and hydrophilic active pharmaceutical ingredients (APIs), their counter-ions (organic, inorganic) and excipients, using a single mixed-mode chromatographic column, and a dual injection approach is presented. Using a mixed-mode Thermo Fisher Acclaim Trinity P1 column, APIs, their counter-ions and possible degradants were first separated using a combination of anion-exchange, cation-exchange and hydrophobic interactions, using a mobile phase consisting of a dual organic modifier/salt concentration gradient. A complementary method was also developed using the same column for the separation of hydrophilic bulk excipients, using hydrophilic interaction liquid chromatography (HILIC) under high organic solvent mobile phase conditions. These two methods were then combined within a single gradient run using dual sample injection, with the first injection at the start of the applied gradient (mixed-mode retention of solutes), followed by a second sample injection at the end of the gradient (HILIC retention of solutes). Detection using both ultraviolet absorbance and refractive index enabled the sensitive detection of APIs and UV-absorbing counter-ions, together with quantitative determination of bulk excipients. The developed approach was applied successfully to the analysis of a dry powder inhalers (Flixotide(®), Spiriva(®)), enabling comprehensive quantification of all APIs and excipients in the sample.

  14. Response behavior of ZrO{sub 2} under swift heavy ion irradiation with and without external pressure

    Energy Technology Data Exchange (ETDEWEB)

    Schuster, B., E-mail: bea.schuster@gsi.de [Technische Universitaet Darmstadt, Hochschulstr. 6, 64289 Darmstadt (Germany); Helmholtz Centre for Heavy Ion Reseach (GSI), Planckstr. 1, 64291 Darmstadt (Germany); Fujara, F. [Technische Universitaet Darmstadt, Hochschulstr. 6, 64289 Darmstadt (Germany); Merk, B. [Technische Universitaet Darmstadt, Hochschulstr. 6, 64289 Darmstadt (Germany); Helmholtz Centre for Heavy Ion Reseach (GSI), Planckstr. 1, 64291 Darmstadt (Germany); Neumann, R. [Helmholtz Centre for Heavy Ion Reseach (GSI), Planckstr. 1, 64291 Darmstadt (Germany); Seidl, T. [Technische Universitaet Darmstadt, Hochschulstr. 6, 64289 Darmstadt (Germany); Helmholtz Centre for Heavy Ion Reseach (GSI), Planckstr. 1, 64291 Darmstadt (Germany); Trautmann, C. [Helmholtz Centre for Heavy Ion Reseach (GSI), Planckstr. 1, 64291 Darmstadt (Germany)

    2012-04-15

    In this study, we demonstrate that the combination of relativistic heavy ions with pressure can influence the phase behavior of ZrO{sub 2} in ways none of those two extreme conditions alone could. The response behavior of ZrO{sub 2} towards ion irradiation under different pressure conditions is investigated. ZrO{sub 2} exposed to energetic particles is known to undergo a crystalline-to-crystalline phase transition from the monoclinic to the tetragonal phase. In agreement with earlier findings, this structural change requires also for heaviest ions, such as Au, Pb, and U, a multiple ion impact. If the irradiation is performed under high pressure, the monoclinic-to-tetragonal transformation occurs at a fluence that is more than one order of magnitude lower suggesting a single impact process. Raman measurements at ambient conditions and X-ray diffraction analysis of the samples irradiated under pressure revealed that the monoclinic-to-tetragonal transformation under pressure is not a direct process but involves a transition into the cubic high-temperature structure, before the tetragonal structure becomes stable under decompression. At even higher pressures, the additional ion irradiation forces ZrO{sub 2} to transform to the higher orthorhombic-II phase that is far away from its stability field.

  15. High-flux ionic diodes, ionic transistors and ionic amplifiers based on external ion concentration polarization by an ion exchange membrane: a new scalable ionic circuit platform.

    Science.gov (United States)

    Sun, Gongchen; Senapati, Satyajyoti; Chang, Hsueh-Chia

    2016-04-07

    A microfluidic ion exchange membrane hybrid chip is fabricated using polymer-based, lithography-free methods to achieve ionic diode, transistor and amplifier functionalities with the same four-terminal design. The high ionic flux (>100 μA) feature of the chip can enable a scalable integrated ionic circuit platform for micro-total-analytical systems.

  16. [Determination of trace and ultra-trace level bromate in water by large volume sample injection with enrichment column for on-line preconcentration coupled with ion chromatography].

    Science.gov (United States)

    Liu, Jing; He, Qingqing; Yang, Lili; Hu, Enyu; Wang, Meifei

    2015-10-01

    A method for the determination of trace and ultra-trace level bromate in water by ion chromatography with large volume sample injection for on-line preconcentration was established. A high capacity Dionex IonPac AG23 guard column was simply used as the enrichment column instead of the loop for the preconcentration of bromate. High purity KOH solution used as eluent for gradient elution was on-line produced by an eluent generator automatically. The results showed that a good linear relationship of bromate was exhibited in the range of 0.05-51.2 μg/L (r ≥ 0.999 5), and the method detection limit was 0.01 μg/L. Compared with conventional sample injection, the injection volume was up to 5 mL, and the enrichment factor of this method was about 240 times. This method was successfully applied for several real samples of pure water which were purchased in the supermarket, and the recoveries of bromate were between 90%-100% with the RSDs (n = 6) of 2.1%-6.4% at two spiked levels. This method without pretreatment is simple, and of high accuracy and precision. The preconcentration can be achieved by large volume sample injection. It is suitable for the analysis of trace and ultra-trace level bromate.

  17. Impurity ion flow and temperature measured in a detached divertor with externally applied non-axisymmetric fields on DIII-D

    Energy Technology Data Exchange (ETDEWEB)

    Briesemeister, A.R., E-mail: briesemeister@fusion.gat.com [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Isler, R.C. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Allen, S.L. [Lawrence Livermore National Laboratory, 700 East Ave, Livermore, CA 94550 (United States); Ahn, J.-W. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States); McLean, A.G. [Lawrence Livermore National Laboratory, 700 East Ave, Livermore, CA 94550 (United States); Unterberg, E.A.; Hillis, D.L. [Oak Ridge National Laboratory, P.O. Box 2008, Oak Ridge, TN 37831 (United States); Fenstermacher, M.E.; Meyer, W.H. [Lawrence Livermore National Laboratory, 700 East Ave, Livermore, CA 94550 (United States)

    2015-08-15

    Externally applied non-axisymmetric magnetic fields are shown to have little effect on the impurity ion flow velocity and temperature as measured by the multichord divertor spectrometer in the DIII-D divertor for both attached and detached conditions. These experiments were performed in H-mode plasmas with the grad-B drift toward the target plates, with and without n = 3 resonant magnetic perturbations (RMPs). The flow velocity in the divertor is shown to change by as much as 30% when deuterium gas puffing is used to create detachment of the divertor plasma. No measurable changes in the C III flow were observed in response to the RMP fields for the conditions used in this work. Images of the C III emission are used along with divertor Thomson scattering to show that the local electron and C III temperatures are equilibrated for the conditions shown.

  18. Salivary-free fluoride ion concentration measured using a flow-injection analysis device and oral environment in 4-6-year-old children.

    Science.gov (United States)

    Iwasaki, Terumi; Uchikawa, Yoshimori; Shirase, Toshiomi

    2016-09-01

    Although fluoride (F) products are widely used for caries prevention, the safest and most effective modes of application, in particular for young children, remain to be elucidated. The limitations associated with the detection of ultra-low F ion concentrations are the major obstacles in accurately assessing the salivary F ion concentrations in children. This study aimed to measure accurate salivary-free F ion concentrations in children using a flow-injection analysis device and highlight the conditions or substances that influence changes in salivary content. Subjects were 4-6-year-old children, and we statistically compared the data involving the number of decayed, missing, or filled surfaces (dmfs), the levels of Mutans streptococci (MS) and Lactobacilli (LB) cariogenic bacteria, and oral hygiene habits. The information on the latter was obtained using a parent/guardian questionnaire. The average free F ion concentration measured was 0.421 ± 0.158 μmol/L (0.008 ± 0.003 ppm), which was considerably lower than that obtained in previous studies using the conventional F electrode method. No significantly different correlations were seen between salivary-free F ion concentrations and dmfs, MS and LB levels. With regard to salivary-free F ion concentrations and oral hygiene habits, only finishing brush of subjects' teeth by guardians showed a significant difference. In summary, the frequency of brushing was shown to correlate with free F ion concentration in saliva of children. Further studies are needed to circumstantially evaluate some other substances in saliva and oral hygiene habits.

  19. Preconcentration and determination of trace silver ion using benzothiazole calix[4]arene modified silica by flow injection flame atomic absorption spectrometry.

    Science.gov (United States)

    Waluvanaruk, Jitwilai; Aeungmaitrepirom, Wanlapa; Tuntulani, Thawatchai; Ngamukot, Passapol

    2014-01-01

    The silica gel modified with benzothiazole calix[4]arene (APS-L1) via Schiff's base reaction was applied as a sorbent in an online system for preconcentration and determination of silver ion by flame atomic absorption spectrometry (FAAS). APS-L1 was used as an effective sorbent for solid phase extraction (SPE) of silver(I) ion in both batch and column methods. The optimum experimental parameters such as pH, eluent type, sample flow rate, eluent volume and eluent flow rate including the effect of interfering ions were investigated. Silver(I) ion was determined at pH 6-7. The capacity of APS-L1 sorbent was found to be 12.2 mg/g of sorbent. The high affinity was obtained without interference from the interfering ions. The optimum conditions of the online flow injection preconcentration coupled with the FAAS (FI-FAAS system) were evaluated. The sample flow rate was 3.0 mL min(-1) using sample volume of 5-10 mL. Elution was performed with 250 μL of 0.1 mol L(-1) thiosulfate at the flow rate of 1.5 mL min(-1). The analytical characteristics and performance of the FI-FAAS system were studied under optimum conditions using a solution spiked with standard silver(I) ion at 20 and 50 μg L(-1). The detection limit of 0.44 μg L(-1) was obtained. The accuracy of the proposed method was evaluated and percentages of recovery at 20 and 50 μg L(-1) were 100.2 and 99.5%, respectively. The percent relative standard deviations (%RSD) at 20 and 50 μg L(-1) were 6.1 and 3.3%, respectively. The developed method was successfully applied to determine trace silver(I) ion in drinking and tap water samples.

  20. Stripping injection of heavy ions in HITFiL synchrotron%HITFiL同步加速器剥离注入

    Institute of Scientific and Technical Information of China (English)

    柴伟平; 夏佳文; 杨建成; 原有进; 石健; 李朋

    2013-01-01

    一台新的治癌专用加速器HITFiL正在设计和建造中,其中一台同步加速器为其主加速器,以高紧凑性、高可靠性和低成本为设计目标.同步加速器的注入系统采用剥离注入方式,剥离注入与单圈注入方式相比能达到较高的注入效率,而其造价明显低于多圈注入加电子冷却的注入方式.治癌采用碳粒子束,从ECR离子源产生的C5+离子经过回旋加速器预加速后在同步加速器注入点处剥离成为C6+注入到环里.详细阐述了该注入系统的设计方案,并对整个注入过程进行了计算机模拟.在模拟过程中,对束流的注入效率、束流损失机制和粒子数增益进行了研究,得到了实空间和相空间的粒子分布和发射度增长趋势,得到了满足要求的束流流强.%A new accelerator dedicated to hadron therapy,the Heavy-Ion Therapy Facility in Lanzhou (HITFiL),is under construction.As the main accelerator of HITFiL,a heavy-ion synchrotron is designed with special attention paid to compact structure,high reliability and low cost.Stripping injection scheme is adopted for the synchrotron,which is more efficient than single-turn injection and less costly than multi-turn injection supported by electron-cooling.Carbon beams are adopted for HITFiL cancer therapy:Cs+ ions from an electron cyclotron resonance ion source,are pre-accelerated by a cyclotron,stripped into C6+ ions by a carbon foil located in a main dipole of the ring and injected into the central orbit of the ring at the same time.The detailed injection scheme for the synchrotron is presented,and the stripping injection process is simulated.The injection efficiency,complete beam loss factors and the particle number gain are investigated.In addition,beam properties including beam distribution in real and phase space and emittance growth due to foil traversal are studied,and the required beam intensity is achieved.

  1. Flow-Injection Amperometric Determination of Tacrine based on Ion Transfer across a Water–Plasticized Polymeric Membrane Interface

    Directory of Open Access Journals (Sweden)

    C. Rueda

    2007-07-01

    Full Text Available A flow-injection pulse amperometric method for determining tacrine, based onion transfer across a plasticized poly(vinyl chloride (PVC membrane, was developed. Afour-electrode potentiostat with ohmic drop compensation was used, while a flow-throughcell incorporated the four electrodes and the membrane, which containedtetrabutylammonium tetraphenylborate. The influence of the applied potential and of theflow-injection variables on the determination of tacrine was studied. In the selectedconditions, a linear relationship between peak height and tacrine concentration was foundup to 4x10-5M tacrine. The detection limit was 1x10-7M. Good repeatability was obtained.Some common ions and pharmaceutical excipients did not interfere.

  2. Influence of changes in external potassium and chloride ions on membrane potential and intracellular potassium ion activity in rabbit ventricular muscle.

    Science.gov (United States)

    Fozzard, H A; Lee, C O

    1976-04-01

    1. The membrane responses of rabbit papillary muscles to rapid changes in [K](o) and [Cl](o) were measured with open-tipped micropipettes and with closed micropipettes made from K-selective glass.2. The muscle cells behaved primarily as a K electrode, and responses to changes in [K](o) with constant [Cl](o) or with constant [K](o) x [Cl](o) were substantially the same.3. When [Cl](o) was changed at a constant [K](o) the membrane potentials changed rapidly and symmetrically by a small value and remained constant for 30 min.4. Measurement of potential with K(+)-selective micro-electrodes in these experiments showed no change in intracellular K activity. In addition to permitting calculation of K permeability, these measurements reassured us that the K(+)-selective electrodes were well insulated and not influenced by electrical shunts at the impalement site.5. Although the membrane response to changes in [Cl](o) was small, it was possible to calculate that the permeability ratio (P(Cl)/P(K)), was 0.11. The Cl and K conductances were about 0.015 mmho/cm(2) and 0.09 mmho/cm(2) respectively, resulting in a conductance ratio (g(Cl)/g(K)) of about 0.17.6. The time course of depolarization by increase in [K](o) was rapid (half-time 5 sec), but repolarization on return to lower [K](o) was much slower (half-time 50 sec). The depolarization time course was easily fitted by the potential change calculated by assuming the need for K diffusion into the extracellular spaces and taking account of the logarithmic relation between membrane potential and [K](o). These calculations did not fit the time course of repolarization, which was slowed in the fashion expected from an inward-rectifying membrane.7. The influence of [K](i) on membrane potential was investigated by changes in tonicity of the external solution. Hypotonic solution produced a change in intracellular K activity close to that produced by ideal water movement. However, in hypertonic solution, intracellular K activity

  3. Characteristics of a high-power RF source of negative hydrogen ions for neutral beam injection into controlled fusion devices

    Science.gov (United States)

    Abdrashitov, G. F.; Belchenko, Yu. I.; Gusev, I. A.; Ivanov, A. A.; Kondakov, A. A.; Sanin, A. L.; Sotnikov, O. Z.; Shikhovtsev, I. V.

    2017-01-01

    An injector of hydrogen atoms with an energy of 0.5-1 MeV and equivalent current of up to 1.5 A for purposes of controlled fusion research is currently under design at the Budker Institute of Nuclear Physics, Siberian Branch, Russian Academy of Sciences. Within this project, a multiple-aperture RF surface-plasma source of negative hydrogen ions is designed. The source design and results of experiments on the generation of a negative ion beam with a current of >1 A in the long-pulse mode are presented.

  4. Metal impurity transport control in JET H-mode plasmas with central ion cyclotron radiofrequency power injection

    DEFF Research Database (Denmark)

    Valisa, M.; Carraro, L.; Predebon, I.

    2011-01-01

    The scan of ion cyclotron resonant heating (ICRH) power has been used to systematically study the pump out effect of central electron heating on impurities such as Ni and Mo in H-mode low collisionality discharges in JET. The transport parameters of Ni and Mo have been measured by introducing a t...

  5. Injection of auxiliary electrons for increasing the plasma density in highly charged and high intensity ion sources

    Science.gov (United States)

    Odorici, F.; Malferrari, L.; Montanari, A.; Rizzoli, R.; Mascali, D.; Castro, G.; Celona, L.; Gammino, S.; Neri, L.

    2016-02-01

    Different electron guns based on cold- or hot-cathode technologies have been developed since 2009 at INFN for operating within ECR plasma chambers as sources of auxiliary electrons, with the aim of boosting the source performances by means of a higher plasma lifetime and density. Their application to microwave discharge ion sources, where plasma is not confined, has required an improvement of the gun design, in order to "screen" the cathode from the plasma particles. Experimental tests carried out on a plasma reactor show a boost of the plasma density, ranging from 10% to 90% when the electron guns are used, as explained by plasma diffusion models.

  6. Injection of auxiliary electrons for increasing the plasma density in highly charged and high intensity ion sources

    Energy Technology Data Exchange (ETDEWEB)

    Odorici, F., E-mail: fabrizio.odorici@bo.infn.it; Malferrari, L.; Montanari, A. [INFN—Bologna, Viale B. Pichat, 6/2, 40127 Bologna (Italy); Rizzoli, R. [INFN—Bologna, Viale B. Pichat, 6/2, 40127 Bologna (Italy); CNR–Istituto per la Microelettronica ed i Microsistemi, Via Gobetti 101, 40129 Bologna (Italy); Mascali, D.; Castro, G.; Celona, L.; Gammino, S.; Neri, L. [INFN–Laboratori Nazionali del Sud, Via S. Sofia 62, 95125 Catania (Italy)

    2016-02-15

    Different electron guns based on cold- or hot-cathode technologies have been developed since 2009 at INFN for operating within ECR plasma chambers as sources of auxiliary electrons, with the aim of boosting the source performances by means of a higher plasma lifetime and density. Their application to microwave discharge ion sources, where plasma is not confined, has required an improvement of the gun design, in order to “screen” the cathode from the plasma particles. Experimental tests carried out on a plasma reactor show a boost of the plasma density, ranging from 10% to 90% when the electron guns are used, as explained by plasma diffusion models.

  7. Coupling on-line preconcentration by ion-exchange with ETAAS. A novel flow injection approach based on the use of a renewable microcolumn as demonstrated for the determination of nickel in environmental and biological samples

    DEFF Research Database (Denmark)

    Wang, Jianhua; Hansen, Elo Harald

    2000-01-01

    A novel way of exploiting flow injection/sequential injection (FIA/SIA) on-line ion-exchange preconcentration with detection by electrothermal atomic absorption spectrometry (ETAAS) is described and demonstrated for the determination of trace-levels of nickel. Based on the use of a renewable...... microcolumn incorporated within an integrated micro FI-system, the column is loaded with a defined volume of small beads of an SP Sephadex C-25 cation-exchange resin and subsequently exposed to a metered amount of sample solution. However, instead of eluting the retained analyte from the organic ion-exchange...

  8. Simultaneous determination of Cr(III) and Cr(VI) in tannery wastewater using low pressure ion chromatography combined with flow injection spectrophotometry

    Science.gov (United States)

    Chen, Shujuan; Zhang, Xinshen; Yu, Lingyun; Wang, Li; Li, Hui

    2012-03-01

    Trivalent and hexavalent chromium have been successfully separated and determined using low pressure ion chromatography combined with flow injection spectrophotometric analysis (LPIC-FIA). A column packed with crosslinking starch microspheres was used for on-line separation of Cr(III) from Cr(VI) in a flow-injection system because of its absorptive effect on Cr(III). To determine the concentration of Cr(III) and Cr(VI) in samples, we used 3.0 mmol/L nitric acid to elute adsorbed Cr(III) from the column and then used ceric sulfate-sulfuric acid as oxidant to convert all Cr(III) into Cr(VI). Then, Cr(VI) directly came from the samples and Cr(VI) came from Cr(III) successively formed a amaranthine complex with diphenycarbazide and the complex shows a maximum absorption at 530 nm. Analytical parameters including the concentration of eluent and oxidant solution, oxidizing temperature, length of oxidizing reaction coil, reaction coil and injection coil, interfering effects, etc., were optimized. The limit of detection was 1.25 μg/L for Cr(VI) and 3.76 μg/L for Cr(III). The linear relationship between absorption with the concentration of Cr(VI) and Cr(III) was 0.001-1.000 mg/L and 0.030-1.000 mg/L with correlation coefficients of 0.9995 and 0.9994, respectively. The relative standard deviation of Cr(VI) and Cr(III) was 1.21% and 1.66%, respectively (n = 10). Major cations and anions did not show any interference. We validated this method through certified reference materials and through measuring the recovery in tannery wastewater.

  9. Evaluation of a novel PTFE material for use as a means for separation and preconcentration of trace levels of metal ions in sequential injection (SI) and sequential injection lab-on-valve (SI-LOV) systems. Determination of cadmium (II) with detection by electrothermal atomic absorption spectrometry

    DEFF Research Database (Denmark)

    Long, Xiangbao; Chomchoei, Roongrat; Hansen, Elo Harald

    2004-01-01

    with an external packed column and in a sequential injection lab-on-valve (SI-LOV) system. Employed for the determination of cadmium(II), complexed with diethyldithiophosphate (DDPA), and detection by electrothermal atomic absorption spectrometry (ETAAS), its performance was compared to that of a previously used...

  10. Ion pair-dispersive liquid-liquid microextraction coupled to microsample injection system-flame atomic absorption spectrometry for determination of gold at trace level in real samples.

    Science.gov (United States)

    Hol, Aysen; Kartal, Aslıhan Arslan; Akdogan, Abdullah; Elçi, Aydan; Arslan, Tuba; Elçi, Lati

    2015-01-01

    A novel ion pair-dispersive liquid-liquid microextraction (IP-DLLME) of gold followed by its determination with microsample injection system-flame atomic absorption spectrometry (MIS-FAAS) detection was developed. The extraction method was based on the reaction of anionic tetrachloro gold(III) complex with the cationic form of Rhodamine B to give a violet ion pair complex, which is extracted from 1.0 mol L(-1) HCl solution of 8.0 mL to fine droplets of chloroform of 500 µL. A Plackett-Burman experimental design of MINITAB statistical program was employed to optimize the influence of main parameters to be controlled in DLLME. After optimizing the extraction conditions, gold was quantitatively recovered by preconcentration factor of 40, limit of detection (LOD) of 1.8 μg L(-1) and relative standard deviation of less than 6.8%. The proposed method was successfully applied to the preconcentration and determination of gold in some samples such as tap water, waste water, copper electrolysis solution and copper wire coated nickel.

  11. Novel PVC-membrane potentiometric sensors based on a recently synthesized sulfur-containing macrocyclic diamide for Cd2+ ion. Application to flow-injection potentiometry.

    Science.gov (United States)

    Shamsipur, Mojtaba; Dezaki, Abbas Shirmardi; Akhond, Morteza; Sharghi, Hashem; Paziraee, Zahra; Alizadeh, Kamal

    2009-12-30

    A new sulfur-containing macrocyclic diamide, 1,15-diaza-3,4,12,13-dibenzo-5,11-dithia-8-oxa-1,15-(2,6-pyrido)cyclooctadecan-2,14-dione, L, was synthesized, characterized and used as an active component for fabrication of PVC-based polymeric membrane (PME), coated graphite (CGE) and coated silver wire electrodes (CWE) for sensing Cd(2+) ion. The electrodes exhibited linear Nernstian responses to Cd(2+) ion in the concentration range of 3.3 x 10(-6) to 3.3 x 10(-1)M (for PME, LOD=1.2 x 10(-6)M), 2.0 x 10(-7) to 3.3 x 10(-1)M (for CWE, LOD=1.3 x 10(-7)M) and 1.6 x 10(-8) to 1.3 x 10(-1)M (for CGE, LOD=1.0 x 10(-8)M). The CGE was used as a proper detection system in flow-injection potentiometry (FIP) with a linear Nernstian range of 3.2 x 10(-8) to 1.4 x 10(-1)M (LOD=1.3 x 10(-8)M). The optimum pH range was 3.5-7.6. The electrodes revealed fairly good discriminating ability towards Cd(2+) in comparison with a large number of alkali, alkaline earth, transition and heavy metal ions. The electrodes found to be chemically inert, showing a fast response time of <5s, and could be used practically over a period of about 2-3 months. The practical utility of the proposed system has also been reported.

  12. Application of a metal ion-imprinted polymer based on salen-Cu complex to flow injection preconcentration and FAAS determination of copper.

    Science.gov (United States)

    Walas, Stanisław; Tobiasz, Anna; Gawin, Marta; Trzewik, Bartosz; Strojny, Marcin; Mrowiec, Halina

    2008-06-30

    A new Cu(II)-imprinted polymer (Cu-IIP) for preconcentration of copper by liquid-solid extraction via flow injection technique has been proposed. Cu-IIP was obtained by copolymerization of salen-Cu(II) complex with styrene and divinylbenzene using suspension polymerization technique. Granules fraction of 60-80 microm in diameter was used as a microcolumn packing. Cu(II) sorption was proved to be the most effective from solutions of pH 7, whereas similar elution effectiveness was observed when applying as eluents hydrochloric or nitric acid in the concentration range of 0.5-10% (v/v). The system exhibited good long-term stability and acid resistance. Batch sorbent capacity was found to be 0.11 mmol g(-1) of a dry polymer. Enrichment factor (EF) for 30 s loading time was 16. Preconcentration of Cu(II) and potentially interfering metal ions is strongly pH dependent. Examination of Cu(II) sorption in the presence of Pb(II), Cd(II), Zn(II) and Ag(I) showed significant influence of cadmium and zinc ions only and that was for the interferent concentrations above 0.5 mg L(-1) (Cu-IIP mass of ca. 35 mg). The interference effect was reduced with the sorbent mass increase. Fe(III) and Mn(II) ions, present in treated tap water in relatively high concentrations, did not interfere. Effective pH adjusting of the loaded solution in on-line mode, when applying diluted Clark-Lubs buffering solution, allowed accurate copper determination in tap water (compared to graphite furnace atomic absorption spectrometry, GFAAS) using standard addition or combination calibration method.

  13. 外注入式独立调谐微波电子枪的概念设计%Conceptual design of independently tunable cells RF gun with external injecting structure

    Institute of Scientific and Technical Information of China (English)

    梁军军; 冯光耀; 裴元吉; 庞健

    2012-01-01

    为得到微脉冲束团长度在百fs量级且高重复频率,设计了一种紧凑型的强流电子枪结构——独立调谐微波热发射电子枪.该电子腔具有双驻波加速腔,两个驻波加速腔之间相互没有耦合,可以分别独立地馈入功率、调节相位.通过优化功率与相位,可以得到较优的束流品质,同时避免了α磁铁和激光系统的使用,使得结构更加紧凑.并采用外注入式结构增大流强、降低能散度,同时消除电子反轰对阴极的负面影响.对不同结构参数的腔体进行1维和3维束流动力学计算,可以得到较为理想的腔体参数.通过调节预注入器的馈入功率和粒子入射相位,可以进一步的压缩束团长度.%To obtain the micro-pulse bunch with the order of hundred femtoseconds length and high repetition rate, the paper proposes the independently tunable cells (ITC) RF gun. Which has a double-cell structure with the cells being power fed independently. By choosing appropriate feeding power and phase of the two cells, this ITC-RF gun can achieve bunches of excellent characteristics. Additionally, the application of α-magnet and laser system can be avoided, which leads to more compact layout. An external injecting ITC-RF gun (DC-ITC-RF gun) structure is designed accordingly. The external injecting structure can increase beam current, decrease energy spread, and cancel the back-bombardment effect almost completely. By means of 1-D and 3-D beam dynamics calculation with different structure parameters, a group of RF parameters are obtained for better beam characteristics. Then the paper designs a pre-injector so that particles can be accelerated to 10 MeV. By choosing appropriate feeding power and incident particle phase for the pre-injector, the bunch length can be further compressed.

  14. 离子色谱法测定复方氨基酸注射液(20AA)中醋酸根%Determination of acetate ion in Compound Amino Acid Injection (20AA) by ion chromatography

    Institute of Scientific and Technical Information of China (English)

    白海娇

    2014-01-01

    目的:建立以氢氧根作为淋洗液的离子色谱法测定复方氨基酸注射液(20AA)中醋酸根的方法。方法使用Dionex ICS 3000离子谱仪,Dionex As19-Ag19阴离子交换色谱柱(250 mm×4 mm),水–30 mmol/L氢氧化钠溶液为淋洗液,梯度洗脱,体积流量1.0 mL/min,柱温30℃,进样量20μL,抑制型电导检测器,检测池温度35℃。结果醋酸根与相邻杂质的分离度为1.8,最低检出浓度0.75μmol/L,线性范围0.75~2.24 mmol/L(r=0.9995),平均回收率为100.7%,RSD值为1.7%。结论该方法操作简单,分离度好,背景低,是控制复方氨基酸注射液(20AA)中醋酸根的可靠方法。%Objective To establish a method for the determination of acetate ion in Compound Amino Acid Injection (20AA) by ion chromatography with hydroxide as mobile phase. Methods Determination was carried out on Dionex As19-Ag19 anion-exchange chromatography column (250 mm × 4 mm) with Dionex ICS 3000 Ion Spectrometer. The elutriant consisted of water-30 mmol/L sodium hydroxide with gradient elution at a flow rate of 1.0 mL/min. The temperature of column was set at 30℃with injection volume of 10μL. Inhibitory electrical conductivity detector was used with detecting pool temperature of 35℃. Results The resolution between acetate ion peak and adjacent peak was 1.8, and LOD was 0.75 μmol/L. The calibration curve was linear in the range of 0.75—2.24 mmol/L (r=0.999 5). The recovery was 100.7%with RSD value of 1.7%(n=9). Conclusion The method is simple with good resolution and low background, and can be used for quality control of acetate ion in Compound Amino Acid Injection (20AA).

  15. A mode converter to generate a Gaussian-like mode for injection into the VENUS electron cyclotron resonance ion source

    Energy Technology Data Exchange (ETDEWEB)

    Lyneis, C., E-mail: CMLyneis@lbl.gov; Benitez, J.; Hodgkinson, A.; Strohmeier, M.; Todd, D. [Nuclear Science Division, Lawrence Berkeley National Laboratory, Berkeley, California 94720 (United States); Plaum, B. [Institut für Grenzflächenverfahrenstechnik und Plasmatechnologie (IGVP), Stuttgart (Germany); Thuillier, T. [Laboratoire de Physique Subatomique et de Cosmologie, Université Joseph Fourier Grenoble 1, CNRS/IN2P3, Institut Polytechnique de Grenoble, 53 rue des martyrs 38026 Grenoble cedex (France)

    2014-02-15

    A number of superconducting electron cyclotron resonance (ECR) ion sources use gyrotrons at either 24 or 28 GHz for ECR heating. In these systems, the microwave power is launched into the plasma using the TE{sub 01} circular waveguide mode. This is fundamentally different and may be less efficient than the typical rectangular, linearly polarized TE{sub 10} mode used for launching waves at lower frequencies. To improve the 28 GHz microwave coupling in VENUS, a TE{sub 01}-HE{sub 11} mode conversion system has been built to test launching HE{sub 11} microwave power into the plasma chamber. The HE{sub 11} mode is a quasi-Gaussian, linearly polarized mode, which should couple strongly to the plasma electrons. The mode conversion is done in two steps. First, a 0.66 m long “snake” converts the TE{sub 01} mode to the TE{sub 11} mode. Second, a corrugated circular waveguide excites the HE{sub 11} mode, which is launched directly into the plasma chamber. The design concept draws on the development of similar devices used in tokamaks and stellerators. The first tests of the new coupling system are described below.

  16. Capillary electrophoresis procedure for the simultaneous analysis and stoichiometry determination of a drug and its counter-ion by using dual-opposite end injection and contactless conductivity detection: application to labetalol hydrochloride.

    Science.gov (United States)

    Nehmé, Reine; Lascaux, Adrien; Delépée, Raphaël; Claude, Bérengère; Morin, Philippe

    2010-03-24

    In this work, a capillary electrophoresis (CE) procedure was developed for the simultaneous determination of a pharmaceutical drug and its counter-ion, namely labetalol hydrochloride. For this purpose, an uncoated fused-silica capillary, a low conductivity background electrolyte (BGE) and a capacitively coupled contactless conductivity detector (C(4)D) were employed. This detection system is highly sensitive and enables detection of inorganic as well as organic ions unlike with direct UV detection. Moreover, to be able to simultaneously analyze the cationic drug (labetalol(+)) and its anionic counter-ion (Cl(-)) in the same electrophoretic run without the need of a coated capillary, a dual-opposite end injection was performed. In this technique, the sample is hydrodynamically injected into both ends of the capillary. This method is simple and easy to perform since the different injection steps are automated by the CE software. This novel CE-C(4)D procedure with dual-opposite end injection has been successfully validated and applied for the analysis of chloride content in an adrenergic antagonist (labetalol hydrochloride). Thus, the hereby developed method has been shown to enable fast (analysis time<10 min), precise (repeatability of migration times<0.7% and of corrected-peak areas < 3.3%; n=6) and rugged analyses for the simultaneous determination of a pharmaceutical drug and its counter-ion. Copyright 2010 Elsevier B.V. All rights reserved.

  17. Matching from H(-) multicusp source to central region of a 100 MeV compact cyclotron for high current injection.

    Science.gov (United States)

    Yao, Hongjuan; Zhang, Tianjue; Lu, Yinlong; Jia, Xianlu; Guan, Fengping; Lin, Yuzheng

    2008-02-01

    The way of matching the beam from an external ion source to the central region of the cyclotron CYCIAE-100 is presented in this article. The transverse acceptances of the central region were calculated, which provided the matching ellipse parameter requirements to the injection transport optics design. The optics of the injection line was simulated using TRANSOPTR, which allowed space charge effect calculation, and neutralization was taken into account.

  18. Method of the ion beam emittance measurement in the injection beam line of DC-72 cyclotron in the presence of its space charge using the scanner to determine beam dimensions

    CERN Document Server

    Kasarinov, N Y; Kalagin, I V; Kazacha, V I

    2002-01-01

    The gradient method for measuring the transversal emittance of a high current ion beam in the injection channel of the cyclotron DC-72 is considered. The standard scanner is proposed for measuring the transversal dimensions of the beam. The formulae for determination of the mean square beam dimensions by current signals from the scanner needle are adduced. The method of the emittance recovery for axial-symmetric ion beam is set for the case when the space charge effect is essential. The algorithm for tuning of the quadrupole lenses in the injection channel of the cyclotron DC-72 for obtaining the axial-symmetric ion beam is proposed. The evaluations of the expected accuracy of the proposed method for the emittance recovery have been carried out.

  19. Evaluation of a novel PTFE material for use as a means for separation and preconcentration of trace levels of metal ions in sequential injection (SI) and sequential injection lab-on-valve (SI-LOV) systems. Determination of cadmium (II) with detection by electrothermal atomic absorption spectrometry

    DEFF Research Database (Denmark)

    Long, Xiangbao; Chomchoei, Roongrat; Hansen, Elo Harald

    2004-01-01

    The operational characteristics of a novel poly(tetrafluoroethylene) (PTFE) bead material, granular Algoflon®, used for separation and preconcentration of metal ions via adsorption of on-line generated non-charged metal complexes, were evaluated in a sequential injection (SI) system furnished...

  20. A novel solidified floating organic drop microextraction method for preconcentration and determination of copper ions by flow injection flame atomic absorption spectrometry.

    Science.gov (United States)

    Sahin, Ciğdem Arpa; Tokgöz, Ilknur

    2010-05-14

    A rapid, simple and cost effective solidified floating organic drop microextraction (SFODME) and flow injection flame atomic absorption spectrometric determination (FI-FAAS) method for copper was developed. In this method, a free microdrop of 1-undecanol containing 1,5-diphenyl carbazide (DPC) as the complexing agent was transferred to the surface of an aqueous sample including Cu(II) ions, while being agitated by a stirring bar in the bulk of the solution. Under the proper stirring conditions, the suspended microdrop can remain at the top-center position of the aqueous sample. After the completion of the extraction, the sample vial was cooled by placing it in a refrigerator for 10min. The solidified microdrop was then transferred into a conical vial, where it melted immediately and diluted to 300microL with ethanol. Finally, copper ions in 200microL of diluted solution were determined by FI-FAAS. Several factors affecting the microextraction efficiency, such as type of extraction solvent, pH, complexing agent concentration, extraction time, stirring rate, sample volume and temperature were investigated and optimized. Under optimized conditions for 100mL of solution, the preconcentration factor was 333 and the enrichment factor was 324. The limit of detection (3s) was 0.4ngmL(-1), the limit of quantification (10s) was 1.1ngmL(-1) and the relative standard deviation (RSD) for 10 replicate measurements of 10ngmL(-1) copper was 0.9%. The proposed method was successfully applied to the determination of copper in different water samples.

  1. Trace analysis of pesticides in paddy field water by direct injection using liquid chromatography-quadrupole-linear ion trap-mass spectrometry.

    Science.gov (United States)

    Pareja, Lucía; Martínez-Bueno, M J; Cesio, Verónica; Heinzen, Horacio; Fernández-Alba, A R

    2011-07-29

    A multiresidue method was developed for the quantification and confirmation of 70 pesticides in paddy field water. After its filtration, water was injected directly in a liquid chromatograph coupled to a hybrid triple quadrupole-linear ion trap-mass spectrometer (QqLIT). The list of target analytes included organophosphates, phenylureas, sulfonylureas, carbamates, conazoles, imidazolinones and others compounds widely used in different countries where rice is cropped. Detection and quantification limits achieved were in the range from 0.4 to 80 ng L(-1) and from 2 to 150 ng L(-1), respectively. Correlation coefficients for the calibration curves in the range 0.1-50 μg L(-1) were higher than 0.99 except for diazinon (0.1-25 μg L(-1)). Only 9 pesticides presented more than 20% of signal suppression/enhancement, no matrix effect was observed in the studied conditions for the rest of the target pesticides. The method developed was used to investigate the occurrence of pesticides in 59 water samples collected in paddy fields located in Spain and Uruguay. The study shows the presence of bensulfuron methyl, tricyclazole, carbendazim, imidacloprid, tebuconazole and quinclorac in a concentration range from 0.08 to 7.20 μg L(-1). Copyright © 2011 Elsevier B.V. All rights reserved.

  2. 复方苦参注射液腹腔内注射联合体外高频热疗对晚期肝癌腹水患者的疗效%Efficacy of Intraperitoneal Injection of Compound Matrine Injection Combined with External High Frequency Thermotherapy for the Treatment of Ascites in Advanced Liver Cancer

    Institute of Scientific and Technical Information of China (English)

    杨柳; 李小妹

    2015-01-01

    目的:探讨复方苦参腹注射液腔内注射联合体外高频热疗对晚期肝癌腹水患者的疗效。方法:选取我院2012年7月~2014年3月收治的确诊为晚期肝癌腹水患者29例的临床资料,按照随机分组的方法分为对照组和观察组。对照组给予复方苦参注射液腔内注射治疗,观察组在对照组的基础上联合体外高频热疗治疗。比较两组治疗总有效率、细胞免疫学指标、生活质量改善率为及不良反应发生情况。结果:治疗后,观察组治疗总有效率高于对照组(73.33% vs 50.00%,χ2=9.003,P<0.05);观察组治疗CD4+/CD8+及NK细胞数均高于对照组(P<0.05);观察组生活质量改善率高于对照组(73.33% vs 35.71%,χ2=10.324,P<0.05)。两组治疗中均未见明显不良反应发生。结论:复方苦参注射液腹腔内注射联合体外高频热疗可提高晚期肝癌腹水患者的治疗总有效率,改善患者的生活质量和免疫力,且不良反应发生率较低。%Objective: To investigate efficacy of intraperitoneal injection of compound matrine injection combined with external high frequency thermotherapy for the treatment of patients with ascites in advanced liver cancer.Methods:29 cases of patients with ascites in advanced liver cancer in the department of oncology in the Huainan east general hospital from July 2012 to March 2014 were randomly divided into the control group and observation group.The control group were treated by compound matrine injection via intraperitoneal injection,the observation group were treated by external high frequency thermotherapy on the base of the control group.The total efifciency rate,the cell immunological parameters,quality of life and adverse events of the two groups were compared.Results:After treatment,the total efifciency rate of observation group was higher than that of the control group(73.33% vs 50.00%,χ2=9.003,P<0.05).The CD4+/CD8+and NK cells of the

  3. On-line ion exchange preconcentration in a sequential injection lab-on-valve microsystem incorporating a renewable column with ETAAS for the trace-level determination of bismuth in urine and river sediment

    DEFF Research Database (Denmark)

    Wang, Jianhua; Hansen, Elo Harald

    2001-01-01

    A sequential injection system for on-line ion-exchange separation and preconcentration of trace-level amounts of metal ions with ensuing detection by electrothermal atomic absorption spectrometry (ETAAS) is described. Based on the use of a renewable microcolumn incorporated within an integrated l.......3% for the determination of 2.0 mug/l Bi (n = 7). The procedure was validated by determination of bismuth in a certified reference material CRM 320 (river sediment), and by bismuth spike recoveries in two human urine samples....

  4. Investigation of multi-charged heavy ion production in an electron beam ion source

    Energy Technology Data Exchange (ETDEWEB)

    Hamm, R.W.

    1977-12-01

    Measurements of multi-charged heavy ions produced in an Electron Beam Ion Source (EBIS) were carried out with a test model ion source 20 cm in length. This test model utilized an electron gun placed external to the bore of the focusing solenoid in order to achieve electrostatically focussed electron beams and isolation of the vacuum surrounding the electron gun from the vacuum in the ionization region within the solenoid bore. An ultrahigh vacuum system utilizing liquid nitrogen (77/sup 0/K) cryopumping was used to achieve the low pressures needed in the ionization region for the operation of this ion source. Several technical problems limited the operation of this test model and prevented a thorough investigation of the ionization processes in the ion source, but the experimental results have shown qualitative agreement with the theoretical calculations for the operation of this type of ion source. Even with the problems of an insufficient vacuum and electron beam focussing field, measurable currents of C/sup +5/ and A/sup +8/ ions were produced. The present experimental results suggest that the approach taken in this work of using an external electron gun and cryopumping in the EBIS to achieve the large electron beam current density and low vacuum necessary for successful operation is a viable one. Such an ion source can be used to create highly-charged heavy ions for injection into a cyclotron or other type of particle accelerator.

  5. Medroxyprogesterone Injection

    Science.gov (United States)

    Medroxyprogesterone intramuscular (into a muscle) injection and medroxyprogesterone subcutaneous (under the skin) injection are used to prevent pregnancy. Medroxyprogesterone subcutaneous injection is also used to treat endometriosis (a condition in which ...

  6. Pentamidine Injection

    Science.gov (United States)

    Pentamidine injection is used to treat pneumonia caused by a fungus called Pneumocystis carinii. It is in ... Pentamidine injection comes as powder to be mixed with liquid to be injected intramuscularly (into a muscle) ...

  7. [Treatment by external insulin pump].

    Science.gov (United States)

    Clavel, Sylvaine

    2010-12-01

    Since the recent recommendations by the French speaking association for research on diabetes and metabolic illnesses (Alfediam), treatment by insulin pump has found itself in competition with basal-bolus, a procedure using similar injections of insulin which has become a benchmark treatment. The latest Alfediam guidelines focus on defining ways of treating diabetics with an external insulin pump.

  8. Cryogenic linear Paul trap for cold highly charged ion experiments.

    Science.gov (United States)

    Schwarz, M; Versolato, O O; Windberger, A; Brunner, F R; Ballance, T; Eberle, S N; Ullrich, J; Schmidt, P O; Hansen, A K; Gingell, A D; Drewsen, M; López-Urrutia, J R Crespo

    2012-08-01

    Storage and cooling of highly charged ions require ultra-high vacuum levels obtainable by means of cryogenic methods. We have developed a linear Paul trap operating at 4 K capable of very long ion storage times of about 30 h. A conservative upper bound of the H(2) partial pressure of about 10(-15) mbar (at 4 K) is obtained from this. External ion injection is possible and optimized optical access for lasers is provided, while exposure to black body radiation is minimized. First results of its operation with atomic and molecular ions are presented. An all-solid state laser system at 313 nm has been set up to provide cold Be(+) ions for sympathetic cooling of highly charged ions.

  9. Cryogenic linear Paul trap for cold highly charged ion experiments

    DEFF Research Database (Denmark)

    Schwarz, Maria; Versolato, Oscar; Windberger, Alexander

    2012-01-01

    Storage and cooling of highly charged ions require ultra-high vacuum levels obtainable by means of cryogenic methods. We have developed a linear Paul trap operating at 4 K capable of very long ion storage times of about 30 h. A conservative upper bound of the H2 partial pressure of about 10−15 mbar...... (at 4 K) is obtained from this. External ion injection is possible and optimized optical access for lasers is provided, while exposure to black body radiation is minimized. First results of its operation with atomic and molecular ions are presented. An all-solid state laser system at 313 nm has been...... set up to provide cold Be+ ions for sympathetic cooling of highly charged ions....

  10. Transient Enhancement ('Spike-on-Tail') Observed on Neutral-Beam-Injected Energetic Ion Spectra Using the E||B Neutral Particle Analyzer in the National Spherical Torus Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Medley, S. S. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Gorelenkov, N. N. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Bell, R. E. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Fredrickson, E. D. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Gerhardt, S. P. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); LeBlanc, B. P. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Podesta, M. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States); Roquemore, A. L. [Princeton Plasma Physics Lab. (PPPL), Princeton, NJ (United States)

    2010-06-01

    An increase of up to four-fold in the E||B Neutral Particle Analyzer (NPA) charge exchange neutral flux localized at the Neutral Beam (NB) injection full energy is observed in the National Spherical Torus Experiment (NSTX). Termed the High-Energy Feature (HEF), it appears on the NB-injected energetic ion spectrum only in discharges where tearing or kink-type modes (f < 10 kHz) are absent, TAE activity (f ~ 10-150 kHz) is weak (δBrms < 75 mGauss) and CAE/GAE activity (f ~ 400 – 1200 kHz) is robust. The feature exhibits a growth time of ~ 20 - 80 ms and occasionally develops a slowing down distribution that continues to evolve over periods of 100's of milliseconds, a time scale long compared with the typical ~ 10's ms equilibration time of the NB injected particles. The HEF is observed only in H-mode (not L-mode) discharges with injected NB power of 4 MW or greater and in the field pitch range v||/v ~ 0.7 – 0.9; i.e. only for passing (never trapped) energetic ions. The HEF is suppressed by vessel conditioning using lithium deposition at rates ~ 100 mg/shot, a level sufficient to suppress ELM activity. Increases of ~ 10 - 30 % in the measured neutron yield and total stored energy are observed to coincide with the feature along with broadening of measured Te(r), Ti(r) and ne(r) profiles. However, TRANSP analysis shows that such increases are driven by plasma profile changes and not the HEF phenomenon itself. Though a definitive mechanism has yet to be developed, the HEF appears to be caused by a form of TAE/CAE wave-particle interaction that distorts of the NB fast ion distribution in phase space.

  11. Ion selective electrodes for penicillin-G based on Mn(III)TPP-Cl and their application in pharmaceutical formulations control by sequential injection analysis.

    Science.gov (United States)

    Santos, Emília M G; Araújo, Alberto N; Couto, Cristina M C M; Montenegro, M Conceição B S M; Kejzlarová, Anna; Solich, Petr

    2004-11-19

    The work describes the construction, evaluation and analytical application of ion selective electrodes sensitive to penicillin-G antibiotics for pharmaceutical products analysis. Different types of polymeric membranes based on PVC (poly(vinyl chloride)) and EVA (ethyl-vinyl-acetate), without internal reference solution, were prepared using 5,10,15,20-tetraphenylporphyrinate (TPP) manganese(III) (Mn(III)TPP-Cl) as electroactive material. Different additives such as tetra-n-octylammoniumbromide (cationic additive) and sodium tetraphenylborate (anionic additive) were incorporated into the membranes to evaluate their influence on electrodes performance. The comparison of the developed detectors was based on general analytical characteristics, selectivity and lifetime. To accomplish the analysis of real samples, two selective membranes composed of 33.0% (w/w) of PVC, 66.0% (w/w) of o-NPOE and 1.0% (w/w) of Mn(III)TPP-Cl (type A) and 33.0% (w/w) of PVC, 66.0% (w/w) of o-NPOE, 1.0% (w/w) of Mn(III)TPP-Cl and 10% mol (relative to the molar concentration of Mn(III)TPP-Cl) of sodium tetraphenylborate (type B) were used. Type A electrode presented a linear response between 2 x 10(-5) and 10(-1) moll(-1) for penicillin-G, a slope of about -59 mVdec(-1) and a reproducibility of about +/-0.5 mVday(-1), while type B exhibited a linear response between 5 x 10(-5) and 10(-1) moll(-1) for penicillin-G, a slope of about -61 mVdec(-1) and a reproducibility of about +/-0.3 mV day(-1). The potentiometric analysis of penicillin-G in pharmaceutical products was carried out by direct potentiometry and the results obtained were compared with those provided by the HPLC reference method. These membranes (type A and type B) were used to prepare tubular electrodes that were coupled to a sequential injection system (SIA) and presented a linear range between 2 x 10(-4) and 1 x 10(-2) moll(-1) and slopes of -59.3 +/- 0.8 and -57.3 +/- 1.2 mVdec(-1), respectively. The tubular electrode constructed

  12. Flow-injection potentiometry by poly(vinyl chloride)-membrane electrodes with diphosphoryl-dicarboxylicacid-p-tert-butylcalix[4]arene ionophore for the determination of Th(IV) ions.

    Science.gov (United States)

    Mizani, Farhang; Shamsipur, Mojtaba; Yaftian, Mohammad R; Matt, Dominique

    2013-01-01

    A new coated ion-selective electrode for the determination of trace thorium ions by flow-injection potentiometry (FIP) has been developed. A poly(vinyl chloride) (PVC)-based membrane was coated on a graphite electrode. The optimum membrane contained 5 wt% diphosphoryl-dicarboxylicacid-p-tert-butylcalix[4]arene (L) as the ionophore, 59 wt% dioctyl phthalate (DOP), 33 wt% PVC and 3 wt% additive sodium tetraphenylborate. The response was linear from 2.0 × 10(-7) to 1.0 × 10(-2) M with a slope of 13.9 mV decade(-1) and a limit of detection of 9.0 × 10(-8) M. The pH-independent region ranged from 3.15 to 6.5, and the lifetime was longer than 8 weeks when used in the flow injection analysis (FIA) system. Selectivity coefficients for several ions were obtained by the separate solutions method. Results showed that, for all cations used, the selectivity coefficients were in the order of 10(-3), or smaller. The flow cell is simple to construct and free from memory effect problems over long periods of use. The proposed sensor was successfully applied to the direct determination of thorium in both real and synthetic samples.

  13. Doripenem Injection

    Science.gov (United States)

    ... injection is in a class of medications called carbapenem antibiotics. It works by killing bacteria.Antibiotics such ... if you are allergic to doripenem injection; other carbapenem antibiotics such as imipenem/cilastatin (Primaxin) or meropenem ( ...

  14. Methotrexate Injection

    Science.gov (United States)

    Methotrexate injection is used alone or in combination with other medications to treat gestational trophoblastic tumors (a ... in bones) after surgery to remove the tumor. Methotrexate injection is also used to treat severe psoriasis ( ...

  15. Bendamustine Injection

    Science.gov (United States)

    Bendamustine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white ... injection. You should use birth control to prevent pregnancy in yourself or your partner during your treatment ...

  16. Caspofungin Injection

    Science.gov (United States)

    Caspofungin injection is used in adults and children 3 months of age and older to treat yeast ... people with a weakened ability to fight infection. Caspofungin injection is in a class of antifungal medications ...

  17. Temozolomide Injection

    Science.gov (United States)

    Temozolomide is used to treat certain types of brain tumors. Temozolomide is in a class of medications called alkylating ... Temozolomide injection comes as a powder to be added to fluid and injected over 90 minutes intravenously ( ...

  18. Pembrolizumab Injection

    Science.gov (United States)

    Pembrolizumab injection is used to treat melanoma (a type of skin cancer) that cannot be treated with ... who have a specific type of melanoma tumor. Pembrolizumab injection is also used to treat a certain ...

  19. Lacosamide Injection

    Science.gov (United States)

    ... injection is in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in ... older (about 1 in 500 people) who took anticonvulsants like lacosamide injection to treat various conditions during ...

  20. Midazolam Injection

    Science.gov (United States)

    ... injection is in a class of medications called benzodiazepines. It works by slowing activity in the brain ... breast-feeding.talk to your doctor about the risks and benefits of receiving midazolam injection if you ...

  1. Doxycycline Injection

    Science.gov (United States)

    Doxycycline injection is used to treat or prevent bacterial infections, including pneumonia and other respiratory tract infections. ... certain skin, genital, intestine, and urinary system infections. Doxycycline injection may be used to treat or prevent ...

  2. Paclitaxel Injection

    Science.gov (United States)

    ... with other medications. Paclitaxel injection manufactured with polyoxyethylated castor oil is used to treat ovarian cancer (cancer that ... cancer, and lung cancer. Paclitaxel injection with polyoxyethylated castor oil is also used to treat Kaposi's sarcoma (a ...

  3. Etanercept Injection

    Science.gov (United States)

    ... will be using the prefilled syringe or automatic injection device, tell your doctor if you or the person who will be injecting the medication for you are allergic to rubber or latex.tell your doctor and pharmacist what ...

  4. Cyclosporine Injection

    Science.gov (United States)

    Cyclosporine injection is used with other medications to prevent transplant rejection (attack of the transplanted organ by ... who have received kidney, liver, and heart transplants. Cyclosporine injection should only be used to treat people ...

  5. Estrogen Injection

    Science.gov (United States)

    The estradiol cypionate and estradiol valerate forms of estrogen injection are used to treat hot flushes (hot ... should consider a different treatment. These forms of estrogen injection are also sometimes used to treat the ...

  6. Cefotaxime Injection

    Science.gov (United States)

    Cefotaxime injection is used to treat certain infections caused by bacteria including pneumonia and other lower respiratory ... skin, blood, bone, joint, and urinary tract infections. Cefotaxime injection may also be used before surgery, and ...

  7. 小针刀加穴位注射治疗肱骨外上髁炎88例临床观察%Clinical Observation of 88 Cases about Treating External Humeral Epicondylitis by Point Injection with a Needle Knife

    Institute of Scientific and Technical Information of China (English)

    金晓平

    2012-01-01

    [目的]观察小针刀加曲安奈德穴位注射治疗肱骨外上髁炎的效果.[方法]小针刀加曲安奈德穴位注射对88例门诊肱骨外上髁炎患者进行治疗.[结果]痊愈54.54%,显效34.1%,好转11.36%,总有效率99.73%.[结论1针药结合的方法对肱骨外上髁炎周围软组织损伤小、疼痛较轻.真正体现中医传统治疗的特色,尤其适用于基层.%[Objective] To observe the effect of treating external humeral epicondylitis by tnamcinolone acetonide point injection with a needle knife. [Method] To treat 88 outpatients for external humeral epicondylitis by tnamcinolone acetonide point injection with a needle knife. [Result] The recovery rate was 54.54%, significant effects 34.1%, improvement 11.36%, and total effective rate 99.73%. [Conclusion] The method of combining needles and medicine does little harm to the soft tissues around external humeral epicondylitis as well as alleviates pain. It reflects the characteristics of the Chinese traditional treatment, especially suitable for the basic level.

  8. Ustekinumab Injection

    Science.gov (United States)

    ... Do not inject into an area where the skin is tender, bruised, red, or hard or where you have scars or stretch marks.Your doctor or pharmacist will ... injection.you should know that ustekinumab injection may decrease your ability ... new or changing skin lesions, minor infections (such as open cuts or ...

  9. Ranitidine Injection

    Science.gov (United States)

    Ranitidine injection comes as a solution (liquid) to be mixed with another fluid and injected intravenously (into a vein) over 5 to 20 minutes. Ranitidine may also be injected into a muscle. It is usually given every 6 to 8 hours, but may also be given ...

  10. Ion slip effect on unsteady Hartmann flow with heat transfer under exponential decaying pressure gradient

    Directory of Open Access Journals (Sweden)

    Hazem A. Attia

    2006-01-01

    Full Text Available The unsteady Hartmann flow of an electrically conducting, viscous, incompressible fluid bounded by two parallel nonconducting porous plates is studied with heat transfer taking the ion slip into consideration. An external uniform magnetic field and a uniform suction and injection are applied perpendicular to the plates, while the fluid motion is subjected to an exponential decaying pressure gradient. The two plates are kept at different but constant temperatures while the Joule and viscous dissipations are included in the energy equation. The effect of the ion slip and the uniform suction and injection on both the velocity and temperature distributions is examined.

  11. External Otitis (Swimmer's Ear)

    Science.gov (United States)

    ... to Pneumococcal Vaccine Additional Content Medical News External Otitis (Swimmer's Ear) By Bradley W. Kesser, MD, Associate ... the Outer Ear Ear Blockages Ear Tumors External Otitis (Swimmer's Ear) Malignant External Otitis Perichondritis External otitis ...

  12. Heavy ion storage rings

    Energy Technology Data Exchange (ETDEWEB)

    Schuch, R.

    1987-01-01

    A brief overview of synchrotron storage rings for heavy ions, which are presently under construction in different accelerator laboratories is given. Ions ranging from protons up to uranium ions at MeV/nucleon energies will be injected into these rings using multiturn injection from the accelerators available or being built in these laboratories. After injection, it is planned to cool the phase space distribution of the ions by merging them with cold electron beams or laser beams, or by using stochastic cooling. Some atomic physics experiments planned for these rings are presented.

  13. Subcutaneous Injections

    DEFF Research Database (Denmark)

    Thomsen, Maria

    This thesis is about visualization and characterization of the tissue-device interaction during subcutaneous injection. The tissue pressure build-up during subcutaneous injections was measured in humans. The insulin pen FlexTouchr (Novo Nordisk A/S) was used for the measurements and the pressure...... build-up was evaluated indirectly from the changes in the flow rate between subcutaneous injections and air injections. This method enabled the tissue counter pressure to be evaluated without a formal clinical study approval. The measurements were coupled to a model for the pressure evolution...

  14. Photoprocess of molecules encapsulated in porous solids X: Photosensitization of zeolite-Y encapsulated tris(2,2'-bipyridine-nickel-(II)ion by phenosafranine adsorbed onto the external surface of the nanoporous host

    Indian Academy of Sciences (India)

    Karuppannan Senthil Kumar; Sudha T; Paramasivam Natarajan

    2014-07-01

    Tris-(2,2'-bipyridine)-nickel-(II) complex ion encapsulated by zeolite-Y host has been synthesized by ship-in-a-bottle method. Photosensitization of nickel(II) complex (Ni(bpy)$^{2+}_{3}$) in the zeolite host by surface adsorbed phenosafranine dye was investigated by time-resolved fluorescence and absorption spectral measurements. Formation of nickel (II)-complex in the super cage of the host was ascertained by XRD, FTIR, solidstate NMR, diffuse reflectance UV-visible absorption spectroscopic techniques and ICP-OES measurements. Phenosafranine dye adsorbed on the external surface of zeolite-Y shows a decrease in fluorescence intensity with increased loading of the nickel(II) complex in zeolite-Y. Time-resolved emission studies show two excited state lifetimes for the photoexcited phenosafranine dye. Average fluorescence lifetimes of the dye in this case do not change with increase in the loading of the nickel(II) complex. However, relative contribution of short lifetime component increases when the amount of encapsulated nickel(II) complex is increased. The zeolite-Y host containing only bipyridyl ligand shows a marked decrease in fluorescence intensity. Fluorescence lifetimes of the dye however do not change with increased loading of bipyridyl while relative contribution of short lifetime component increases with an increase in the loading of bipyridyl in the host. This observation is interpreted to be due to electron transfer from the excited state of phenosafranine dye to the bipyridine. Picosecond pump-probe investigations confirm that the photoinduced electron transfer occurs from the surfaceadsorbed phenosafranine in the excited state to the nickel(II) complex within zeolite-Y cavity and also to the Ni(bpy)$^{2+}_{3}$ complex in contact with the phenosafranine dye co-adsorbed on the external surface of the host.

  15. Externally Wetted Ionic Liquid Thruster

    Science.gov (United States)

    Lozano, P.; Martinez-Sanchez, M.; Lopez-Urdiales, J. M.

    2004-10-01

    This paper presents initial developments of an electric propulsion system based on ionic liquid ion sources (ILIS). Propellants are ionic liquids, which are organic salts with two important characteristics; they remain in the liquid state at room temperature and have negligible vapor pressure, thus allowing their use in vacuum. The working principles of ILIS are similar to those of liquid metal ion sources (LMIS), in which a Taylor cone is electrostatically formed at the tip of an externally wetted needle while ions are emitted directly from its apex. ILIS have the advantage of being able to produce negative ions that have similar masses than their positive counterparts with similar current levels. This opens up the possibility of achieving plume electrical neutrality without electron emitters. The possible multiplexing of these emitters is discussed in terms of achievable thrust density for applications other than micro-propulsion.

  16. Injection MD

    CERN Document Server

    Bartmann, W; Bracco, C; Drosdal, L; Gianfelice, E; Goddard, B; Kain, V; Papaphilippou, Y; Vanbavinckhove, G

    2012-01-01

    This note summarizes the results obtained at injection during the 2nd MD block and the floating MD block in July. Highlights are presented for injection in the LHC with the Q20 SPS optics, influence of the supercycle and injection with 25 ns bunch spacing. Beams were successfully injected into the LHC using the Q20 optics [1, 3]. Small corrections were needed to steer the beam in the transfer lines. Dispersion measurements were conducted for both beams. The horizontal normalized dispersion in TI2 was a factor 2 smaller for Q20 with respect to Q26, for TI8 on the other hand the opposite was observed. The results for injection loss dependency on super cycle composition show only a small increase in losses for beam 2. The losses observed must therefore mainly come from other sources such as shot-by-shot stability or quality of scraping. For the injection with 25 ns bunch spacing bunches were injected for both beams. For B1 up to the maximum of 288 bunches. For B2 on the other only up to 144 bunches were injected...

  17. Subcutaneous Injections

    DEFF Research Database (Denmark)

    Thomsen, Maria

    This thesis is about visualization and characterization of the tissue-device interaction during subcutaneous injection. The tissue pressure build-up during subcutaneous injections was measured in humans. The insulin pen FlexTouchr (Novo Nordisk A/S) was used for the measurements and the pressure...... build-up was evaluated indirectly from the changes in the flow rate between subcutaneous injections and air injections. This method enabled the tissue counter pressure to be evaluated without a formal clinical study approval. The measurements were coupled to a model for the pressure evolution...... in subcutaneous tissue, based on mass conservation and flow in a porous medium. From the measurements the flow permeability and bulk modulus of the tissue were determined. In the adipose tissue the drug forms a bolus from where it is absorbed by the blood capillaries. The spatial distribution of the injected...

  18. Injection System design for a hadron therapy Synchrotron

    Institute of Scientific and Technical Information of China (English)

    ZHANG Jin-Quan; SONG Ming-Tao; WEI Bao-Wen

    2008-01-01

    A synchrotron is designed for tumour therapy with C6+ ions or proton.Its injector is a cyclotron, which delivers C5+or H+2 ions to the synchrotron.After comparing the methods of the single-turn injection, the multi-turn injection and the stripping injection,this paper chooses the stripping injection method.In addition,the concept design of the injection system is presented,in which the synchrotron lattice is optimized.

  19. Dosimetric Considerations to Determine the Optimal Technique for Localized Prostate Cancer Among External Photon, Proton, or Carbon-Ion Therapy and High-Dose-Rate or Low-Dose-Rate Brachytherapy

    Energy Technology Data Exchange (ETDEWEB)

    Georg, Dietmar, E-mail: Dietmar.Georg@akhwien.at [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Hopfgartner, Johannes [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Gòra, Joanna [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Kuess, Peter [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Kragl, Gabriele [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Berger, Daniel [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Hegazy, Neamat [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Goldner, Gregor; Georg, Petra [Department of Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria); Christian Doppler Laboratory for Medical Radiation Research for Radiation Oncology, Medical University of Vienna/Allgemeines Krankenhaus der Stadt Wien, Vienna (Austria)

    2014-03-01

    Purpose: To assess the dosimetric differences among volumetric modulated arc therapy (VMAT), scanned proton therapy (intensity-modulated proton therapy, IMPT), scanned carbon-ion therapy (intensity-modulated carbon-ion therapy, IMIT), and low-dose-rate (LDR) and high-dose-rate (HDR) brachytherapy (BT) treatment of localized prostate cancer. Methods and Materials: Ten patients were considered for this planning study. For external beam radiation therapy (EBRT), planning target volume was created by adding a margin of 5 mm (lateral/anterior–posterior) and 8 mm (superior–inferior) to the clinical target volume. Bladder wall (BW), rectal wall (RW), femoral heads, urethra, and pelvic tissue were considered as organs at risk. For VMAT and IMPT, 78 Gy(relative biological effectiveness, RBE)/2 Gy were prescribed. The IMIT was based on 66 Gy(RBE)/20 fractions. The clinical target volume planning aims for HDR-BT ({sup 192}Ir) and LDR-BT ({sup 125}I) were D{sub 90%} ≥34 Gy in 8.5 Gy per fraction and D{sub 90%} ≥145 Gy. Both physical and RBE-weighted dose distributions for protons and carbon-ions were converted to dose distributions based on 2-Gy(IsoE) fractions. From these dose distributions various dose and dose–volume parameters were extracted. Results: Rectal wall exposure 30-70 Gy(IsoE) was reduced for IMIT, LDR-BT, and HDR-BT when compared with VMAT and IMPT. The high-dose region of the BW dose–volume histogram above 50 Gy(IsoE) of IMPT resembled the VMAT shape, whereas all other techniques showed a significantly lower high-dose region. For all 3 EBRT techniques similar urethra D{sub mean} around 74 Gy(IsoE) were obtained. The LDR-BT results were approximately 30 Gy(IsoE) higher, HDR-BT 10 Gy(IsoE) lower. Normal tissue and femoral head sparing was best with BT. Conclusion: Despite the different EBRT prescription and fractionation schemes, the high-dose regions of BW and RW expressed in Gy(IsoE) were on the same order of magnitude. Brachytherapy techniques

  20. Mepolizumab Injection

    Science.gov (United States)

    ... or do not go away: pain, redness, swelling, warmth, burning, or itching in the place mepolizumab was injected headache dry and itchy skin with or without red, scaly rashes back pain muscle spasms Some side ...

  1. Metoclopramide Injection

    Science.gov (United States)

    ... and feeling of fullness that lasts long after meals. Metoclopramide injection is also used to prevent nausea ... tranylcypromine (Parnate); narcotic medications for pain; sedatives; sleeping pills; tetracycline (Bristacycline, Sumycin); tranquilizers. Your doctor may need ...

  2. Ramucirumab Injection

    Science.gov (United States)

    ... dose of ramucirumab injection. Tell your doctor or nurse if you experience any of the following while you receive ramucirumab: uncontrollable shaking of a part of the body; back pain or spasms; chest pain and tightness; chills; flushing; ...

  3. Alemtuzumab Injection

    Science.gov (United States)

    Alemtuzumab injection is used to treat B-cell chronic lymphocytic leukemia (a slowly developing cancer in which ... of white blood cell accumulate in the body). Alemtuzumab is in a class of medications called monoclonal ...

  4. Ferumoxytol Injection

    Science.gov (United States)

    Ferumoxytol injection is used to treat iron-deficiency anemia (a lower than normal number of red blood ... pharmacist what other prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or ...

  5. Fludarabine Injection

    Science.gov (United States)

    Fludarabine injection is used to treat chronic lymphocytic leukemia (CLL; a type of cancer of the white ... a reliable method of birth control to prevent pregnancy during this time. Talk to your doctor for ...

  6. Insulin Injection

    Science.gov (United States)

    ... or buttocks. Do not inject insulin into muscles, scars, or moles. Use a different site for each ... you are using insulin.Alcohol may cause a decrease in blood sugar. Ask your doctor about the ...

  7. Tigecycline Injection

    Science.gov (United States)

    ... in a person who was not in the hospital), skin infections, and infections of the abdomen (area between the ... that developed in people who were in a hospital or foot infections in people who have diabetes. Tigecycline injection is ...

  8. Golimumab Injection

    Science.gov (United States)

    Golimumab injection is used alone or with other medications to relieve the symptoms of certain autoimmune disorders ( ... did not help or could not be tolerated. Golimumab is in a class of medications called tumor ...

  9. Albiglutide Injection

    Science.gov (United States)

    ... will develop tumors of the thyroid gland, including medullary thyroid carcinoma (MTC; a type of thyroid cancer). ... symptoms or those listed in the IMPORTANT WARNING section, stop using albiglutide injection and call your doctor ...

  10. Dexamethasone Injection

    Science.gov (United States)

    ... body tissues,) gastrointestinal disease, and certain types of arthritis. Dexamethasone injection is also used for diagnostic testing. ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  11. Hydrocortisone Injection

    Science.gov (United States)

    ... own organs), gastrointestinal disease, and certain types of arthritis. Hydrocortisone injection is also used to treat certain ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  12. Methylprednisolone Injection

    Science.gov (United States)

    ... own organs), gastrointestinal disease, and certain types of arthritis. Methylprednisolone injection is also used to treat certain ... effects.tell your doctor if you have a fungal infection (other than on your skin or nails). ...

  13. Glatiramer Injection

    Science.gov (United States)

    ... To inject glatiramer, follow these steps: Remove one blister pack from the carton of glatiramer syringes and place ... paper label and remove the syringe from the blister pack. Check your prefilled syringe to be sure it ...

  14. Dexrazoxane Injection

    Science.gov (United States)

    ... that are used to treat or prevent certain side effects that may be caused by chemotherapy medications. Dexrazoxane injection (Zinecard) is used to prevent or decrease heart damage caused by doxorubicin in women who are ...

  15. Evolocumab Injection

    Science.gov (United States)

    ... autoinjector in hot water, microwave, or place in sunlight.Before you use evolocumab injection, look at the ... chills pain or burning during urination muscle or back pain dizziness stomach pain Some side effects can be ...

  16. Cidofovir Injection

    Science.gov (United States)

    Cidofovir injection is used along with another medication (probenecid) to treat cytomegaloviral retinitis (CMV retinitis) in people with acquired immunodeficiency syndrome (AIDS). Cidofovir is in a class of medications called antivirals. ...

  17. Brivaracetam Injection

    Science.gov (United States)

    ... older. Brivaracetam in a class of medications called anticonvulsants. It works by decreasing abnormal electrical activity in ... older (about 1 in 500 people) who took anticonvulsants like brivaracetam injection to treat various conditions during ...

  18. Diphenhydramine Injection

    Science.gov (United States)

    ... not to use diphenhydramine injection if you are breastfeeding because of the risk of harm to infants.tell your doctor if you have or have ever had asthma or other types of lung disease; glaucoma (a ...

  19. Cefazolin Injection

    Science.gov (United States)

    ... valve, respiratory tract (including pneumonia), biliary tract, and urinary tract infections. Cefazolin injection also may be used before, during, ... to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( ...

  20. Ceftazidime Injection

    Science.gov (United States)

    ... skin, blood, bone, joint, female genital tract, and urinary tract infections. Ceftazidime injection is in a class of medications ... to learn about take-back programs in your community. See the FDA's Safe Disposal of Medicines website ( ...

  1. Fluconazole Injection

    Science.gov (United States)

    ... and fungal infections of the eye, prostate (a male reproductive organ), skin and nails. Fluconazole injection is ... Motrin, others) and naproxen (Aleve, Anaprox, Naprelan); oral contraceptives (birth control pills); oral medication for diabetes such ...

  2. Moxifloxacin Injection

    Science.gov (United States)

    ... available.Moxifloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing the bacteria that cause ... you are allergic to moxifloxacin, other quinolone or fluoroquinolone antibiotics such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available ...

  3. Levofloxacin Injection

    Science.gov (United States)

    ... available. Levofloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. ... severe reaction to levofloxacin; any other quinolone or fluoroquinolone antibiotic such as ciprofloxacin (Cipro), gatifloxacin (Tequin) (not available ...

  4. Ciprofloxacin Injection

    Science.gov (United States)

    ... available. Ciprofloxacin injection is in a class of antibiotics called fluoroquinolones. It works by killing bacteria that cause infections. ... reaction to ciprofloxacin or any other quinolone or fluoroquinolone antibiotic such as gatifloxacin (Tequin) (not available in the ...

  5. Alirocumab Injection

    Science.gov (United States)

    ... further decrease the amount of low-density lipoprotein (LDL) cholesterol ('bad cholesterol') in the blood. Alirocumab injection is ... antibodies. It works by blocking the production of LDL cholesterol in the body to decrease the amount of ...

  6. Chloramphenicol Injection

    Science.gov (United States)

    ... an arm or leg sudden changes in vision pain with eye movement Chloramphenicol injection may cause a condition called gray syndrome in premature and newborn infants. There have also been reports of gray ...

  7. Observation on curative effect of external antibacterial washing with Chinese medcine combined with interferonα2b injection in the treatment of flat warts%中药抗菌剂联合干扰素α2b注射液治疗扁平疣疗效观察

    Institute of Scientific and Technical Information of China (English)

    李星汇; 吕东; 秦萍萍; 刘润秋; 曹丽华; 周洋; 晓婷

    2015-01-01

    目的:观察外用中药抗菌剂联合干扰素α2b注射液治疗扁平疣的疗效。方法:将90例入选的扁平疣患者随机分为三组。观察组:30例,应用中药抗菌剂联合干扰素α2b注射液治疗扁平疣;对照1组和2组:各30例,单独应用中药抗菌剂治疗及单独应用干扰素α2b注射液治疗,比较三组疗效及复发率。结果:观察组疗效优于两对照组,复发率低于两对照组,差异均有统计学意义(P<0.05),三组均未见明显的不良反应。结论:应用中药抗菌剂联合干扰素α2b注射液治疗扁平疣具有安全、有效的特点,疗效明显高于单独使用中药抗菌剂或干扰素α2b注射液,且复发率低,可以作为临床医生的一线选择。%Objective To observe the curative effect of external antibacterial washing with Chinese medcine combined with interferon α2b injection in the treatment of flat warts. Methods Ninety patients with flat warts were randomly divided into three groups.Thirty patients in the combination group received external antibacterial washing with Chinese medcine with interferon α2b injection;the others two in the control groups received only one of these treatments,then observe the effects and relapse rates of these three groups. Results The effective rate of treatment group was significantly higher than the control groups,and the relapse rate of treatment group was significantly lower than the control groups,the above showed significant difference(P<0.05).There was no siginificant side effects in these three groups. Conclusion External antibacterial washing with Chinese medcine combined with interferon α2b injection in the treatment of flat warts had better effect,low relapse rate and high safety,it is worthy of clinical application.

  8. External ionization mechanisms for advanced thermionic converters

    Science.gov (United States)

    Hatziprokopiou, M. E.

    Ion generation and recombination mechanisms in the cesium plasma were investigated as they pertain to the advanced mode thermionic energy converters. The changes in plasma density and temperature within the converter were studied under the influence of several promising auxiliary ionization candidate sources. Three novel approaches of external cesium ion generation were investigated in some detail, namely vibrationally excited N2 as an energy source of ionization of Cs ions in a DC discharge, microwave power as a means of resonant sustenance of the cesium plasma, and ion generation in a pulse N2-Cs mixture. The experimental data obtained and discussed in this work show that all three techniques--i.e. the non-LTE high-voltage pulsing, the energy transfer from vibrationally excited diatomic gases, and the external pumping with a microwave power--have considerable promise as schemes in auxiliary ion generation applicable to the advanced thermionic energy converter.

  9. Ion focusing

    Energy Technology Data Exchange (ETDEWEB)

    Cooks, Robert Graham; Baird, Zane; Peng, Wen-Ping

    2017-01-17

    The invention generally relates to apparatuses for focusing ions at or above ambient pressure and methods of use thereof. In certain embodiments, the invention provides an apparatus for focusing ions that includes an electrode having a cavity, at least one inlet within the electrode configured to operatively couple with an ionization source, such that discharge generated by the ionization source is injected into the cavity of the electrode, and an outlet. The cavity in the electrode is shaped such that upon application of voltage to the electrode, ions within the cavity are focused and directed to the outlet, which is positioned such that a proximal end of the outlet receives the focused ions and a distal end of the outlet is open to ambient pressure.

  10. Production and ion-ion cooling of highly charged ions in electron string ion source.

    Science.gov (United States)

    Donets, D E; Donets, E D; Donets, E E; Salnikov, V V; Shutov, V B; Syresin, E M

    2009-06-01

    The scheme of an internal injection of Au atoms into the working space of the "Krion-2" electron string ion source (ESIS) was applied and tested. In this scheme Au atoms are evaporated from the thin tungsten wire surface in vicinity of the source electron string. Ion beams with charge states up to Au51+ were produced. Ion-ion cooling with use of C and O coolant ions was studied. It allowed increasing of the Au51+ ion yield by a factor of 2. Ions of Kr up to charge state 28+ were also produced in the source. Electron strings were first formed with injection electron energy up to 6 keV. Methods to increase the ESIS ion output are discussed.

  11. Metallic ions in organs of rats injected with metallic particles of stainless steel 316L and Ti6Al4V alloy

    Directory of Open Access Journals (Sweden)

    Silvia Helena Giertz

    2010-03-01

    Full Text Available Despite the interest in identifying systemic effects caused by the metallic particles released from long term metallic implants in the body, few works support reliable conclusions about the effects of those particles in organs. The aim of the present work is to look for damages in tissues of liver, kidney, lung and heart of rats submitted to injection of Hank's solution contained particles of Ti6Al4V alloy and Stainless Steel 316L, obtained by metal friction. The particles size ranges from 50 to 200 µm for the Ti alloy and from 100 to 500 µm for the 316L. Tissues isolated from the organs after the euthanasia were prepared and analyzed in an optical microscope and Energy Dispersive Spectrometer (EDS. Lesions caused by an inflammatory response such as strange body epithelioid granuloma and giant cells were found in some of the tissues containing yttrium and aluminum.

  12. Using PVC ion-selective electrodes for the potentiometric flow injection analysis of distigmine in its pharmaceutical formulation and biological fluids

    Directory of Open Access Journals (Sweden)

    Yousry M. Issa

    2011-01-01

    Full Text Available The construction and electrochemical response characteristics of poly(vinylchloride (PVC membrane selective electrodes for the determination of distigmine (Ds are described. The sensing membrane comprised an ion-pair based on distigmine phosphomolybdate (Ds-PM, distigmine phosphotungstate (Ds-PT, distigmine silicomolybdate (Ds-SM, distigmine silicotungstate (Ds-ST, distigmine tetraphenylborate (Ds-TPB, and distigmine reineckate (Ds-Rein in a plasticized PVC matrix with dioctylphthalate (DOP. The influence of membrane composition on the electrodes’ response was studied. The electrodes showed a fast, stable and Nernstian response over a wide distigmine concentration range 5.0 × 10−7–1 × 10−2 mol L−1 with a slope of ∼30.5 ± 1.0 mV dec−1. The response is independent of the pH of test solution within the range 3.8–10.5. The life span of the electrodes extends to at least 2 months without any considerable divergence in potential and has a fast response time of <15 s. The electrodes showed good selectivity towards distigmine with respect to large numbers of ions in batch and FIA systems. The electrodes have been applied to the determination of distigmine in pure solution, pharmaceutical compound and human urine. The dissolution profile for Ubretid tablets (5 mg/tablet was studied.

  13. 外切内注辅助改良 PPH 术治疗环状混合痔的临床研究%External Excision and Internal Injection Sclerotherapy-Assisted Improved Procedure for Prolapsed Hemorrhoids for Circumferential Mixed Hemorrhoids

    Institute of Scientific and Technical Information of China (English)

    丛章龙; 武雅坤; 柳越冬

    2014-01-01

    目的:探讨外切内注辅助改良 PPH 术治疗环状混合痔的近期疗效。方法将符合环状混合痔纳入标准的142例患者按不同术式分为2组,治疗组(70例)采用外切内注辅助改良 PPH 术,对照组(72例)采用内扎内注外切术。观察2组病例术后24 h 疼痛程度、出血情况,术后第3天肛缘水肿、肛门坠胀、肛门狭窄和尿潴留等并发症发生情况。记录术后住院时间、恢复正常生活或工作时间。结果2组患者术后24 h 疼痛评分、出血情况、术后3 d肛门水肿、肛门坠胀及术后住院时间和恢复正常工作或生活时间差异有统计学意义(P <0.01),术后尿潴留发生率差异无统计学意义(P >0.05)。2组患者治愈率均为100%,术后近期均未发生肛门失禁、肛门狭窄及直肠阴道漏等严重并发症,远期疗效有待观察。结论外切内注辅助改良 PPH 在治疗环状混合痔疼痛程度轻,术后并发症少,恢复快,近期疗效优势明显。%Objective To explore the short-term effects of external excision and internal injec-tion sclerotherapy-assisted improved procedure for prolapsed hemorrhoids(PPH)on circumferen-tial mixed hemorrhoids.Methods A total of 142 patients with circumferential mixed hemorrhoids were divided into two groups.The treatment group(n=70)received external excision and internal injection sclerotherapy-assisted improved PPH.The control group(n=72)received internal liga-tion,internal injection sclerotherapy and external excision.The pain and bleeding were observed at 24 hours after operation.The anal margin edema,anal pendant expansion,anal stenosis,urinary retention and other complications were observed at 3 days after operation.In addition,the length of postoperative hospital stay and time to resuming to normal living or working were recorded. Results Pain score and bleeding at 24 hours after operation,anal margin edema and anal pendant expansion at 3

  14. Secondary particle simulation analysis of high-energy56Fe ion inject various shielding material%高能56Fe离子入射屏蔽材料的次级粒子模拟分析

    Institute of Scientific and Technical Information of China (English)

    荀明珠; 何承发; 陆妩; 郭旗; 孙静; 刘默寒; 曾骏哲; 王信

    2016-01-01

    Background: The heavy ion in the galaxy cosmos rays with extremely high energy can be fatal to the astronaut and electronic device in the spacecraft. Purpose:This study aims to analyze the secondary particles produced by high energy heavy ion inject shielding materials of spacecraft.Methods:Based on the Monte-Carlo method simulation software Geant4, 1-GeV·u−156Fe ion incident four kinds of shielding material aluminum, aluminum carbon, polyethylene and water with 1.35-g·cm−2 mass thickness have been studied. The energy deposition in the absorber and deep-dose distribution produced by the transmitted primary particles and secondary electrons, secondary neutrons, secondary protons and secondary gamma have been analyzed. All produced secondary heavy particles and energies from four kinds of shielding materials after injected high-energy 1-GeV·u−156Fe ion have been investigated, and the shielding performance was analyzed and compared.Results:Polyethylene material absorbs the most energy, thus preserve best shielding performance whilst majority of secondary particles and energies are produced. The energy of secondary heavy ion is quadruple of that produced by aluminum material.Conclusion: Among all the secondary particles, secondary protons and secondary heavy ions with atom number between 22 and 26 make the maximal contributions.%空间辐射环境下的高能重离子入射屏蔽材料会产生大量次级粒子,为研究屏蔽材料产生的次级粒子对太空舱内辐射环境的影响,本文使用基于蒙特卡罗方法的Geant4软件模拟空间高能56Fe离子入射铝、碳、聚乙烯、水4种屏蔽材料,分析透射屏蔽体的初级粒子及由屏蔽材料产生的次级电子、次级中子、次级质子和次级γ的能谱以及水吸收体中的能量沉积和深度剂量分布。分析产生的次级重粒子类型和能量,比较4种屏蔽材料对高能Fe离子的屏蔽性能。结果表明,聚乙烯材料对高能重离子的

  15. 光电外反馈与互注入混沌保密系统研究%Chaotic secure communication system based on photoelectric external feedback&mutual injection

    Institute of Scientific and Technical Information of China (English)

    周俊; 张跃进

    2013-01-01

    Chaos synchronization method based on the photoelectric outside feedback and mutual injection technology,passed a small amount of synchronization information,and it is extremely difficult to recover the chaotic systems by intercepted pulse signal,it effectively improved security of the confidentiality communication.So we analyzed the principle of the system,designed the system model and did system simulation and analysis.Simulation results show that the system has high security and timeliness.%基于光电外反馈与互注入技术的混沌同步方法,所传同步信息较少,被截取后获得的脉冲信号恢复出混沌系统的难度极大,有效提高了保密通信的安全性.在分析光电外反馈与互注入混沌系统原理的基础上,设计了系统模型并进行了系统的仿真实验与分析.仿真结果表明,该系统具有较高的安全性和时效性.

  16. The External Degree.

    Science.gov (United States)

    Houle, Cyril O.

    This book examines the external degree in relation to the extremes of attitudes, myths, and data. Emphasis is placed on the emergence of the American external degree, foreign external-degree programs, the purpose of the external degree, the current scene, institutional issues, and problems of general policy. (MJM)

  17. Microfabricated ion frequency standard

    Science.gov (United States)

    Schwindt, Peter; Biedermann, Grant; Blain, Matthew G.; Stick, Daniel L.; Serkland, Darwin K.; Olsson, III, Roy H.

    2010-12-28

    A microfabricated ion frequency standard (i.e. an ion clock) is disclosed with a permanently-sealed vacuum package containing a source of ytterbium (Yb) ions and an octupole ion trap. The source of Yb ions is a micro-hotplate which generates Yb atoms which are then ionized by a ultraviolet light-emitting diode or a field-emission electron source. The octupole ion trap, which confines the Yb ions, is formed from suspended electrodes on a number of stacked-up substrates. A microwave source excites a ground-state transition frequency of the Yb ions, with a frequency-doubled vertical-external-cavity laser (VECSEL) then exciting the Yb ions up to an excited state to produce fluorescent light which is used to tune the microwave source to the ground-state transition frequency, with the microwave source providing a precise frequency output for the ion clock.

  18. A novel solidified floating organic drop microextraction method for preconcentration and determination of copper ions by flow injection flame atomic absorption spectrometry in water samples

    Directory of Open Access Journals (Sweden)

    Arpa Şahin Ç.

    2013-04-01

    Full Text Available A simple, rapid and inexpensive solidified floating organic drop microextraction (SFODME and flow injection flame atomic absorption spectrometric determination (FI-FAAS method for copper was developed. 3-amino-7-dimethylamino-2-methylphenazine (Neutral red, NR was used as the complexing agent. Several factors affecting the microextraction efficiency, such as, pH, NR and sodium dodecylbenzenesulfonate (SDBS concentration, extraction time, stirring rate, and temperature were investigated and optimized. Under optimized experimental conditions an enrichment factor of 541 was obtained for 100 mL of sample solution. The calibration graph was linear in the range of 0.5 – 20.0 ng mL–1 and the limit of detection (3s was 0.18 ng mL–1, the limit of quantification (10s was 0.58 ng mL–1. The relative standard deviation (RSD for 10 replicate measurements of 10 ng mL–1 copper was 2.7%. The developed method was successfully applied to the extraction and determination of copper in different certified reference materials (Estuarine water, Slew 3 and fortified water, TM 23.2 and real water samples and satisfactory results were obtained.

  19. Poly(ester sulphonic acid) coated mercury thin film electrodes: characterization and application in batch injection analysis stripping voltammetry of heavy metal ions.

    Science.gov (United States)

    Brett, C M; Fungaro, D A

    2000-01-10

    Mercury-thin film electrodes coated with a thin film of poly(ester sulphonic acid) (PESA) have been investigated for application in the analysis of trace heavy metals by square wave anodic stripping voltammetry using the batch injection analysis (BIA) technique. Different polymer dispersion concentrations in water/acetone mixed solvent are investigated and are characterised by electrochemical impedance measurements on glassy carbon and on mercury film electrodes. The influence of electrolyte anion, acetate or nitrate, on polymer film properties is demonstrated, acetate buffer being shown to be preferable for stripping voltammetry applications. Although stripping currents are between 30 and 70% less at the coated than at bare mercury thin film electrodes, the influence of model surfactants on stripping response is shown to be very small. The effect of the composition of the modifier film dispersion on calibration plots is shown; however, detection limits of around 5 nM are found for all modified electrodes tested. This coated electrode is an alternative to Nafion-coated mercury thin film electrodes for the analysis of trace metals in complex matrices, particularly useful when there is a high concentration of non-ionic detergents.

  20. Using neutral beams as a light ion beam probe (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xi, E-mail: chenxi@fusion.gat.com [Oak Ridge Institute for Science and Education, Oak Ridge, Tennessee 37831 (United States); Heidbrink, W. W. [University of California Irvine, Irvine, California 92697 (United States); Van Zeeland, M. A.; Pace, D. C.; Petty, C. C.; Fisher, R. K. [General Atomics, P.O. Box 85608, San Diego, California 92186-5608 (United States); Kramer, G. J.; Nazikian, R. [Princeton Plasma Physics Laboratory, P.O. Box 451, Princeton, New Jersey 08543 (United States); Austin, M. E. [University of Texas at Austin, Austin, Texas 78712 (United States); Hanson, J. M. [Columbia University, New York, New York 10027 (United States); Zeng, L. [University of California Los Angeles, Los Angeles, California 90095 (United States)

    2014-11-15

    By arranging the particle first banana orbits to pass near a distant detector, the light ion beam probe (LIBP) utilizes orbital deflection to probe internal fields and field fluctuations. The LIBP technique takes advantage of (1) the in situ, known source of fast ions created by beam-injected neutral particles that naturally ionize near the plasma edge and (2) various commonly available diagnostics as its detector. These born trapped particles can traverse the plasma core on their inner banana leg before returning to the plasma edge. Orbital displacements (the forces on fast ions) caused by internal instabilities or edge perturbing fields appear as modulated signal at an edge detector. Adjustments in the q-profile and plasma shape that determine the first orbit, as well as the relative position of the source and detector, enable studies under a wide variety of plasma conditions. This diagnostic technique can be used to probe the impact on fast ions of various instabilities, e.g., Alfvén eigenmodes (AEs) and neoclassical tearing modes, and of externally imposed 3D fields, e.g., magnetic perturbations. To date, displacements by AEs and by externally applied resonant magnetic perturbation fields have been measured using a fast ion loss detector. Comparisons with simulations are shown. In addition, nonlinear interactions between fast ions and independent AE waves are revealed by this technique.

  1. Sarilumab Injection

    Science.gov (United States)

    ... the needle. Do not try to warm the medication by heating it in a microwave, placing it in warm water or in direct sunlight, or through any other method.Before injecting, check the prefilled syringe to be sure that the expiration date printed on the package has not passed. Look ...

  2. Enfuvirtide Injection

    Science.gov (United States)

    ... inject enfuvirtide into any skin that has a tattoo, scar, bruise, mole, a burn site, or has ... Enfuvirtide may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: itching, swelling, pain, tingling, discomfort, ...

  3. Fluorouracil Injection

    Science.gov (United States)

    ... of a doctor who is experienced in giving chemotherapy medications for cancer. Treatment with fluorouracil injection may cause serious side effects. ... this medication.If you experience a serious side effect, you or your doctor ... (FDA) MedWatch Adverse Event Reporting program online (http://www.fda.gov/ ...

  4. Lanreotide Injection

    Science.gov (United States)

    Lanreotide injection is used to treat people with acromegaly (condition in which the body produces too much growth hormone, causing enlargement of the hands, feet, and facial features; joint pain; and other symptoms) who have not successfully, or cannot be treated ...

  5. Paliperidone Injection

    Science.gov (United States)

    ... the body slow movements or shuffling walk painful erection of the penis that lasts for hours cough, chills and/or other signs of infection Paliperidone injection may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.If you experience a ...

  6. Ziprasidone Injection

    Science.gov (United States)

    ... stiffness falling confusion sweating loss of consciousness painful erection of the penis that lasts for hours Ziprasidone injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a ...

  7. Risperidone Injection

    Science.gov (United States)

    ... control slow movements or shuffling walk falling painful erection of the penis that lasts for hours Risperidone extended-release injection may cause other side effects. Call your doctor if you have any unusual problems while receiving this medication.If you experience a ...

  8. Efficacy of Haihuomie Injection against Internal and external Parasites in Pig%害获灭注射剂对猪体内外寄生虫的驱虫试验

    Institute of Scientific and Technical Information of China (English)

    白生芳; 雷萌桐

    2012-01-01

    Pigs which naturally infected with parasites were injected Haihuomie subcutaneously at dosage of 0.2, 0.3,0.4mg/kg of pig~ body respectively. The results showed that at dosage of 0.2mg/kg , the effect of against parasites was midium, after 7,14d. But at dosage of 0.3,0.4mg/kg, deworming of Asearis suum was 100.00% respectively, and did not happen recurrence in several month. At dosage of 0.2mg/kg, reductive rate of against Haematopinus suis is 89.57%, at dosage of 0.3,0.4mg/kg,is 100% through manure detection after 14d. The experiment proved that 0.3,0.4mg/kg of Haihuomie were effective and safe for deworming Haematopinus suis and Ascaris suum.%应用害获灭注射剂分别按0.2、0.3、0.4mg/kg剂量经皮下注射给药,进行对猪自然感染寄生虫的驱除效果观察。结果:在给药后7、14d临床检查,0.2mg/kg剂量对猪血虱驱虫效果达中效;0.3、0.4mg/kg剂量对猪血虱的驱虫率均达100.00%,用药后至出栏的几个月内未出现复发。在给药后14d粪检,0.2mg/kg剂量组对猪蛔虫虫卵减少率为89.57%;0.3、0.4mg/kg组虫卵减少率均达100.00%。表明害获灭注射剂0.3、0.4mg/kg剂量驱除猪蛔虫和猪血虱高效安全。

  9. Clinical Observation on Intra-articular Injection of Sodium Hyaluronate Combined with External Application of Traditional Chinese Medicine in Treatment of Knee Osteoarthritis%玻璃酸钠关节腔内注射联合中药外敷治疗膝骨性关节炎临床观察

    Institute of Scientific and Technical Information of China (English)

    杨忠良

    2015-01-01

    目的:观察膝骨性关节炎应用玻璃酸钠关节腔内注射与中药外敷联合治疗的临床效果。方法选取我院2013年2月~2014年2月间收治的膝骨性关节炎患者37例,对照组单纯应用玻璃酸钠关节腔内注射治疗,观察组应用玻璃酸钠关节腔内注射与中药外敷联合治疗,比较两组ROM变化、膝关节功能Lysholm评分与治疗效果。结果观察组ROM变化与膝关节功能Lysholm评分改善显著,总有效率(94.44%)与对照组(78.95%)比较相对较高,两组治疗效果差异显著,有统计学意义(P<0.05)。结论膝骨性关节炎应用玻璃酸钠关节腔内注射与中药外敷联合治疗效果满意,安全性高,切实可行,值得推广。%Objective Clinical efficacy of intra-articular injection of sodium hyaluronate combined with external application of traditional Chinese medicine in treatment of knee osteoarthritis is to be observed. Methods Choose 37 patients suffering from knee osteoarthritis who are treated in hospital from February 2013 to February 2014 to study; patients in control group are given intra-articular injection of sodium hyaluronate treatment only; while patients in study group are given intra-articular injection of sodium hyaluronate combined with external application of traditional Chinese medicine treatment;and then observe and compare ROM changes,Lysholm score of keen function and treatment efficacy in these two groups . Results Patients’ ROM changes and Lysholm score of knee function in study group have a better improvement than those in control group;and in addition,treatment efficacy in study group(94.44%)is much higher than that in control group(78.95%);there is a treatment differential between two groups,and such a differential has statistic value(P<0.05). Conclusions Intra-articular injection of sodium hyaluronate combined with external application of traditional Chinese medicine is of efficacy and medical safety in

  10. Subcutaneous (SQ) injections

    Science.gov (United States)

    SQ injections; Sub-Q injections; Diabetes subcutaneous injection; Insulin subcutaneous injection ... NIH. Giving a subcutaneous injection . Rockville, MD. National ... of Health and Human Services NIH publications; 2015. Available ...

  11. Regulating multiple externalities

    DEFF Research Database (Denmark)

    Waldo, Staffan; Jensen, Frank; Nielsen, Max

    2016-01-01

    Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory instrume......Open access is a well-known externality problem in fisheries causing excess capacity and overfishing. Due to global warming, externality problems from CO2 emissions have gained increased interest. With two externality problems, a first-best optimum can be achieved by using two regulatory...

  12. Staging and laser acceleration of ions in underdense plasma

    Science.gov (United States)

    Ting, Antonio; Hafizi, Bahman; Helle, Michael; Chen, Yu-Hsin; Gordon, Daniel; Kaganovich, Dmitri; Polyanskiy, Mikhail; Pogorelsky, Igor; Babzien, Markus; Miao, Chenlong; Dover, Nicholas; Najmudin, Zulfikar; Ettlinger, Oliver

    2017-03-01

    Accelerating ions from rest in a plasma requires extra considerations because of their heavy mass. Low phase velocity fields or quasi-electrostatic fields are often necessary, either by operating above or near the critical density or by applying other slow wave generating mechanisms. Solid targets have been a favorite and have generated many good results. High density gas targets have also been reported to produce energetic ions. It is interesting to consider acceleration of ions in laser-driven plasma configurations that will potentially allow continuous acceleration in multiple consecutive stages. The plasma will be derived from gaseous targets, producing plasma densities slightly below the critical plasma density (underdense) for the driving laser. Such a plasma is experimentally robust, being repeatable and relatively transparent to externally injected ions from a previous stage. When optimized, multiple stages of this underdense laser plasma acceleration mechanism can progressively accelerate the ions to a high final energy. For a light mass ion such as the proton, relativistic velocities could be reached, making it suitable for further acceleration by high phase velocity plasma accelerators to energies appropriate for High Energy Physics applications. Negatively charged ions such as antiprotons could be similarly accelerated in this multi-staged ion acceleration scheme.

  13. A multipassage spectrometer for the study of electron-ion interactions in the EBIS

    Science.gov (United States)

    Kleinod, M.; Dietrich, J.; Lakatos, A.; Langbein, I.; Becker, R.

    1992-04-01

    A multipassage magnetic spectrometer has been constructed which allows selection of a specific high charge state from the extracted ion pulse of our electron beam ion source (EBIS) and to reinject it in the emptied source, now using the electron beam of meanwhile changed energy as a target of free electrons for the study of ionization, dielectronic recombination (DR), or radiative electron capture (REC). The spectrometer consists of a H-magnet with round pole pieces and 4 identical arrangements of achromatic lenses and mirrors under 90° forming a versatile ion switchyard with the possibility of recirculation. The chromaticity of the recirculating transport system and the dispersion of this spectrometer are adjustable by electric potentials on suitably placed electrostatic deflectors inside of the magnetic field. For the injection of ions from an external ion source into the EBIS and to the beam lines, the mirror potentials are pulsed accordingly.

  14. ExternE National Implementation Finland

    Energy Technology Data Exchange (ETDEWEB)

    Pingoud, K.; Maelkki, H.; Wihersaari, M.; Pirilae, P. [VTT Energy, Espoo (Finland); Hongisto, M. [Imatran Voima Oy, Vantaa (Finland); Siitonen, S. [Ekono Energy Ltd, Espoo (Finland); Johansson, M. [Finnish Environment Institute, Helsinki (Finland)

    1999-07-01

    ExternE National Implementation is a continuation of the ExternE Project, funded in part by the European Commission's Joule III Programme. This study is the result of the ExternE National Implementation Project for Finland. Three fuel cycles were selected for the Finnish study: coal, peat and wood-derived biomass, which together are responsible for about 40% of total electricity generation in Finland and about 75% of the non-nuclear fuel based generation. The estimated external costs or damages were dominated by the global warming (GW) impacts in the coal and peat fuel cycles, but knowledge of the true GW impacts is still uncertain. From among other impacts that were valued in monetary terms the human health damages due to airborne emissions dominated in all the three fuel cycles. Monetary valuation for ecosystem impacts is not possible using the ExternE methodology at present. The Meri-Pori power station representing the coal fuel cycle is one of the world's cleanest and most efficient coal-fired power plants with a condensing turbine. The coal is imported mainly from Poland. The estimated health damages were about 4 mECU/kWh, crop damages an order of magnitude lower and damages caused to building materials two orders of magnitude lower. The power stations of the peat and biomass fuel cycles are of CHP type, generating electricity and heat for the district heating systems of two cities. Their fuels are of domestic origin. The estimated health damages allocated to electricity generation were about 5 and 6 mECU/kWh, respectively. The estimates were case-specific and thus an generalisation of the results to the whole electricity generation in Finland is unrealistic. Despite the uncertainties and limitations of the methodology, it is a promising tool in the comparison of similar kinds of fuel cycles, new power plants and pollution abatement technologies and different plant locations with each other. (orig.)

  15. Towards spin injection into silicon

    Energy Technology Data Exchange (ETDEWEB)

    Dash, S.P.

    2007-08-15

    Si has been studied for the purpose of spin injection extensively in this thesis. Three different concepts for spin injection into Si have been addressed: (1) spin injection through a ferromagnet-Si Schottky contact, (2) spin injection using MgO tunnel barriers in between the ferromagnet and Si, and (3) spin injection from Mn-doped Si (DMS) as spin aligner. (1) FM-Si Schottky contact for spin injection: To be able to improve the interface qualities one needs to understand the atomic processes involved in the formation of silicide phases. In order to obtain more detailed insight into the formation of such phases the initial stages of growth of Co and Fe were studied in situ by HRBS with monolayer depth resolution.(2) MgO tunnel barrier for spin injection into Si: The fabrication and characterization of ultra-thin crystalline MgO tunnel barriers on Si (100) was presented. (3) Mn doped Si for spin injection: Si-based diluted magnetic semiconductor samples were prepared by doping Si with Mn by two different methods i) by Mn ion implantation and ii) by in-diffusion of Mn atoms (solid state growth). (orig.)

  16. Determination of trace inorganic anions in dietary alkali by ion chromatography with direct injection%直接进样离子色谱法测定食用碱中痕量无机阴离子

    Institute of Scientific and Technical Information of China (English)

    娄斌; 李阳; 马玲玲; 吕金凤; 唐清

    2011-01-01

    Trace inorganic anions in dietary alkali were directly injected and analyzed by Dionex ICS - 1000 ion-chromatograph and Dionex AS14 column with 3.5 mmol/L Na2CO3 - 1.0 mmol/L NaHCO3 as eluent.This method didn't need sample pretreatment and the existence of high concentrated sodium carbonate will not impact the determination of trace anions due to direct sample injection and conductivity detection.Detection limits for inorganic anions were all lower than 0.012 6 mg/L.Linear correlation coefficient was at 0.998 5 ~ 0.999 8.Relative standard deviation ( RSD ) was at 1.153% ~3.218% ( n =5 ).Standard sample recovery rate was at 93.77% ~96.00% which accorded with analysis and measurement requirements.%用Dionex ICS-1000离子色谱仪,Dionex AS14阴离子分离柱,以3.5 mmol/L碳酸钠-1.0 mmol/L碳酸氢钠为淋洗液,直接进样分析食用碱中的痕量无机阴离子.该法无需样品前处理,直接进样,电导检测,高浓度碳酸钠的存在不影响痕量阴离子的测定.所测的无机阴离子的检出限均在0.012 6 mg/L以下,线性相关系数为0.998 5~0.999 8,相对标准偏差为1.153%-3.218%(n=5),回收率为93.77%~96.00%,符合分析测定要求.

  17. 清开灵注射液联合小儿清肺化痰颗粒治疗小儿上呼吸道感染风热证100例%The clinical effect and segurity of Qingkailing injection in combination with Qingfeihuatan particles in treatment of pediatrics upper respiratory tract infection External wind-heat syndrome

    Institute of Scientific and Technical Information of China (English)

    潘鸿

    2015-01-01

    目的:观察和评价清开灵注射液联合小儿清肺化痰颗粒治疗小儿上呼吸道感染风热证的临床疗效及安全性.方法:采用随机对照试验设计,将200例患儿随机分为治疗组和对照组各100例.对照组给予利巴韦林注射液静脉滴注,治疗组给予清开灵注射液滴注联合口服小儿清肺化痰颗粒治疗,两组患儿疗程为5~7天.评定治疗后两组总有效率,观察药物退热起效时间、体温恢复正常时间及安全性.结果:治疗结束时,治疗组总有效率为95.00%,对照组总有效率为78.00%,差异有统计学意义(P0.05).结论:清开灵注射液联合小儿清肺化痰颗粒治疗小儿上呼吸道感染风热证安全性好,可显著缩短退热起效时间及体温恢复正常时间,且疗效优于利巴韦林注射液.%Objective:To abserve and evaluate the clinical effect and segurity of Qingkailing injection in combination with Qingfeihuatan particles in treatment of pediatrics upper respiratory tract infection External wind-heat syndrome. Methods: With randomized controlled trial design, 200 cases were randomly divided into a treatment group(100cases) and a controlled group(100cases).The controlled group was treated with ribavirin injection ,the treatment group was treated with Qingkailing injection in combination with Qingfeihuatan particles. The treatment course for 5 to 7 days.Evaluate total effective rate of two groups after treatment.To observe the onset time of the drug, the time of body temperature returned to normal and the safety. Results: At the end of the treatment, the total effective rate of treatment group was 95.00%, controlled group was 78.00%, the difference was statistically significant (P0.05). Conclusion: Qingkailing injection in combination with Qingfeihuatan particles in treatment of pediatris upper respiratory tract infection External wind-heat syndrome can significantly shorten the onset time and the time of body temperature returned to normal, and

  18. Enhanced acceleration of injected electrons in a laser-beat-wave-induced plasma channel.

    Science.gov (United States)

    Tochitsky, S Ya; Narang, R; Filip, C V; Musumeci, P; Clayton, C E; Yoder, R B; Marsh, K A; Rosenzweig, J B; Pellegrini, C; Joshi, C

    2004-03-05

    Enhanced energy gain of externally injected electrons by a approximately 3 cm long, high-gradient relativistic plasma wave (RPW) is demonstrated. Using a CO2 laser beat wave of duration longer than the ion motion time across the laser spot size, a laser self-guiding process is initiated in a plasma channel. Guiding compensates for ionization-induced defocusing (IID) creating a longer plasma, which extends the interaction length between electrons and the RPW. In contrast to a maximum energy gain of 10 MeV when IID is dominant, the electrons gain up to 38 MeV energy in a laser-beat-wave-induced plasma channel.

  19. ASH External Web Portal (External Portal) -

    Data.gov (United States)

    Department of Transportation — The ASH External Web Portal is a web-based portal that provides single sign-on functionality, making the web portal a single location from which to be authenticated...

  20. Reliable operation of the Brookhaven EBIS for highly charged ion production for RHIC and NSRL

    Energy Technology Data Exchange (ETDEWEB)

    Beebe, E., E-mail: beebe@bnl.gov; Alessi, J., E-mail: beebe@bnl.gov; Binello, S., E-mail: beebe@bnl.gov; Kanesue, T., E-mail: beebe@bnl.gov; McCafferty, D., E-mail: beebe@bnl.gov; Morris, J., E-mail: beebe@bnl.gov; Okamura, M., E-mail: beebe@bnl.gov; Pikin, A., E-mail: beebe@bnl.gov; Ritter, J., E-mail: beebe@bnl.gov; Schoepfer, R., E-mail: beebe@bnl.gov [Brookhaven National Laboratory, Upton, NY 11973 (United States)

    2015-01-09

    An Electron Beam Ion Source for the Relativistic Heavy Ion Collider (RHIC EBIS) was commissioned at Brookhaven in September 2010 and since then it routinely supplies ions for RHIC and NASA Space Radiation Laboratory (NSRL) as the main source of highly charged ions from Helium to Uranium. Using three external primary ion sources for 1+ injection into the EBIS and an electrostatic injection beam line, ion species at the EBIS exit can be switched in 0.2 s. A total of 16 different ion species have been produced to date. The length and the capacity of the ion trap have been increased by 20% by extending the trap by two more drift tubes, compared with the original design. The fraction of Au{sup 32+} in the EBIS Au spectrum is approximately 12% for 70-80% electron beam neutralization and 8 pulses operation in a 5 Hertz train and 4-5 s super cycle. For single pulse per super cycle operation and 25% electron beam neutralization, the EBIS achieves the theoretical Au{sup 32+} fractional output of 18%. Long term stability has been very good with availability of the beam from RHIC EBIS during 2012 and 2014 RHIC runs approximately 99.8%.

  1. Reliable operation of the Brookhaven EBIS for highly charged ion production for RHIC and NSRL

    Science.gov (United States)

    Beebe, E.; Alessi, J.; Binello, S.; Kanesue, T.; McCafferty, D.; Morris, J.; Okamura, M.; Pikin, A.; Ritter, J.; Schoepfer, R.

    2015-01-01

    An Electron Beam Ion Source for the Relativistic Heavy Ion Collider (RHIC EBIS) was commissioned at Brookhaven in September 2010 and since then it routinely supplies ions for RHIC and NASA Space Radiation Laboratory (NSRL) as the main source of highly charged ions from Helium to Uranium. Using three external primary ion sources for 1+ injection into the EBIS and an electrostatic injection beam line, ion species at the EBIS exit can be switched in 0.2 s. A total of 16 different ion species have been produced to date. The length and the capacity of the ion trap have been increased by 20% by extending the trap by two more drift tubes, compared with the original design. The fraction of Au32+ in the EBIS Au spectrum is approximately 12% for 70-80% electron beam neutralization and 8 pulses operation in a 5 Hertz train and 4-5 s super cycle. For single pulse per super cycle operation and 25% electron beam neutralization, the EBIS achieves the theoretical Au32+ fractional output of 18%. Long term stability has been very good with availability of the beam from RHIC EBIS during 2012 and 2014 RHIC runs approximately 99.8%.

  2. Quasi-stable injection channels in a wakefield accelerator

    Science.gov (United States)

    Wiltshire-Turkay, Mara; Farmer, John P.; Pukhov, Alexander

    2016-05-01

    The influence of initial position on the acceleration of externally injected electrons in a plasma wakefield is investigated. Test-particle simulations show previously unobserved complex structure in the parameter space, with quasi-stable injection channels forming for particles injected in narrow regions away from the wake centre. Particles injected into these channels remain in the wake for a considerable time after dephasing and as a result achieve significantly higher energy than their neighbours. The result is relevant to both the planning and optimisation of experiments making use of external injection.

  3. 艾迪注射液联合体外高频热疗治疗恶性肠梗阻临床研究%Clinical Research on Aidi Injection Combined with External High Frequency Thermotherapy for the Treatment of Malignant Bowel Obstruction

    Institute of Scientific and Technical Information of China (English)

    潘金华

    2012-01-01

    Objective: To observe the clinical efficacy of Aidi injection combined with external high frequency thermotherapy for the treatment of malignant bowel obstruction. Methods: 60 cases of malignant bowel obstruction (They were both abdominal and pelvic tumor patients who had the surgery,with 29 cases of colon cancer,9 cases of rectal cancer, 16 cases of gastric cancer and 6 cases of ovarian cancer) were divided into the control group and treatment group with the method of random number table. Two groups of patients were given basic treatment of chemotherapy. The treatment group was additionally given Aidi injection combined with external high frequency thermotherapy on the basis of chemotherapy. The clinical efficacy and prognosis of the patients in two groups were observed and recorded. Results: After four cycles of treatment,the efficiency rate of curative effects,improvement rate of quality of life and the six - month survival rate of the treatment group was significantly higher than that of the control group (P < 0. 05). Conclusion: Aidi injection combined with external high frequency thermotherapy treatment for malignant bowel obstruction can effectively enhance the clinical efficacy of patients and improve the patient's quality of life and survival rate.%目的:观察艾迪注射液联合体外高频热疗治疗恶性肠梗阻的临床疗效.方法:将60例恶性肠梗阻患者(均为腹腔、盆腔肿瘤术后患者,其中结肠癌29例,直肠癌9例,胃癌16例,卵巢癌6例)按随机数字表法分为对照组30例和治疗组30例.两组患者均给予基础化疗,治疗组在化疗方案的基础上,采用艾迪注射液联合体外高频热疗法治疗,观察记录两组患者的临床疗效及预后.结果:经过4个周期治疗后,治疗组患者的近期疗效有效率、生活质量改善率及6个月生存率均明显高于对照组(P<0.05).结论:艾迪注射液联合体外高频热疗治疗恶性肠梗阻能有效提高患者的临床疗效,更

  4. Neutral Beam Injection for Plasma and Magnetic FieldDiagnostics

    Energy Technology Data Exchange (ETDEWEB)

    Vainionpaa, Jaakko Hannes; Leung, Ka Ngo; Kwan, Joe W.; Levinton,Fred

    2007-08-01

    At the Lawrence Berkeley National Laboratory (LBNL) adiagnostic neutral beam injection system for measuring plasma parameters,flow velocity, and local magnetic field is being developed. High protonfraction and small divergence is essential for diagnostic neutral beams.In our design, a neutral hydrogen beam with an 8 cm x 11 cm (or smaller)elliptical beam spot at 2.5 m from the end of the extraction column isproduced. The beam will deliver up to 5 A of hydrogen beam to the targetwith a pulse width of ~;1 s, once every 1 - 2 min. The H1+ ion species ofthe hydrogen beamwill be over 90 percent. For this application, we havecompared two types of RF driven multicusp ion sources operating at 13.56MHz. The first one is an ion source with an external spiral antennabehind a dielectric RF-window. The second one uses an internal antenna insimilar ion source geometry. The source needs to generate uniform plasmaover a large (8 cm x 5 cm) extraction area. We expect that the ion sourcewith internal antenna will be more efficient at producing the desiredplasma density but might have the issue of limited antenna lifetime,depending on the duty factor. For both approaches there is a need forextra shielding to protect the dielectric materials from the backstreaming electrons. The source walls will be made of insulator materialsuch as quartz that has been observed to generate plasma with higheratomic fraction than sources with metal walls. The ion beam will beextracted and accelerated by a set of grids with slits, thus forming anarray of 6 sheet-shaped beamlets. The multiple grid extraction will beoptimized using computer simulation programs. Neutralization of the beamwill be done in neutralization chamber, which has over 70 percentneutralization efficiency.

  5. Direct injection ion chromatography for the control of chlorinated drinking water: simultaneous estimation of nine haloacetic acids and quantitation of bromate, chlorite and chlorate along with the major inorganic anions.

    Science.gov (United States)

    Garcia-Villanova, Rafael J; Raposo Funcia, César; Oliveira Dantas Leite, M Vilani; Toruño Fonseca, Ivania M; Espinosa Nieto, Miguel; Espuelas India, Javier

    2014-09-01

    Most methods for the analysis of haloacetic acids published in recent years are based on ion chromatography with direct injection, employing a gradient elution with potassium hydroxide (KOH). This work reports the exploration of an alternative eluent, a buffer of sodium carbonate/sodium hydrogen carbonate, aimed at the simultaneous analysis of nine haloacetic acids along with bromate, chlorite and chlorate. The alternative of both a less alkaline eluent and a lower temperature of operation may prevent the partial decomposition of some of the haloacetic acids during the analytical process, especially the more vulnerable brominated ones. Gradient elution at temperature of 7 °C yielded the best results, with an acceptable separation of 17 analytes (which includes the major natural inorganic anions) and a good linearity. Precision ranges from 0.3 to 23.4 (% V.C.), and detection limits are within units of μg L⁻¹, except for tribromoacetic acid - somewhat high in comparison with those of the official methods. Nonetheless, with the basic instrumentation setup herein described, this method may be suitable for monitoring when the drinking water treatments are to be optimized. This is especially interesting for small communities or for developing/developed countries in which regulations on disinfection by-products others than trihalomethanes are being addressed.

  6. Measurement and analysis of internal loss and injection efficiency for continuous-wave blue semipolar ( 20 2 ¯ 1 ¯ ) III-nitride laser diodes with chemically assisted ion beam etched facets

    Science.gov (United States)

    Becerra, Daniel L.; Kuritzky, Leah Y.; Nedy, Joseph; Saud Abbas, Arwa; Pourhashemi, Arash; Farrell, Robert M.; Cohen, Daniel A.; DenBaars, Steven P.; Speck, James S.; Nakamura, Shuji

    2016-02-01

    Continuous-wave blue semipolar ( 20 2 ¯ 1 ¯ ) III-nitride laser diodes were fabricated with highly vertical, smooth, and uniform mirror facets produced by chemically assisted ion beam etching. Uniform mirror facets are a requirement for accurate experimental determination of internal laser parameters, including internal loss and injection efficiency, which were determined to be 9 cm-1 and 73%, respectively, using the cavity length dependent method. The cavity length of the uncoated devices was varied from 900 μm to 1800 μm, with threshold current densities ranging from 3 kA/cm2 to 9 kA/cm2 and threshold voltages ranging from 5.5 V to 7 V. The experimentally determined internal loss was found to be in good agreement with a calculated value of 9.5 cm-1 using a 1D mode solver. The loss in each layer was calculated and in light of the analysis several modifications to the laser design are proposed.

  7. Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry.

    Science.gov (United States)

    Liu, Chunhua; Ju, Aichun; Zhou, Dazheng; Li, Dekun; Kou, Junping; Yu, Boyang; Qi, Jin

    2016-05-18

    YiQiFuMai injection (YQFM) is a modern lyophilized powder preparation derived from the traditional Chinese medicine Sheng-mai san (SMS) used for treating cardiovascular diseases, such as chronic heart failure. However, its chemical composition has not been fully elucidated, particularly for the preparation derived from Ophiopogon japonicus. This study aimed to establish a systematic and reliable method to quickly and simultaneously analyze the chemical constituents in YQFM by ultra-fast liquid chromatography coupled with ion trap time-of-flight mass spectrometry (UFLC-IT-TOF/MS). Sixty-five compounds in YQFM were tentatively identified by comparison with reference substances or literature data. Furthermore, twenty-one compounds, including three ophiopogonins, fifteen ginsenosides and three lignans were quantified by UFLC-IT-TOF/MS. Notably, this is the first determination of steroidal saponins from O. japonicus in YQFM. The relative standard deviations (RSDs) of intra- and inter-day precision, reproducibility and stability were analysis of ten batches of YQFM. The developed approach can provide useful and comprehensive information for quality control, further mechanistic studies in vivo and clinical application of YQFM.

  8. Simultaneous Qualitative and Quantitative Analysis of Multiple Chemical Constituents in YiQiFuMai Injection by Ultra-Fast Liquid Chromatography Coupled with Ion Trap Time-of-Flight Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Chunhua Liu

    2016-05-01

    Full Text Available YiQiFuMai injection (YQFM is a modern lyophilized powder preparation derived from the traditional Chinese medicine Sheng-mai san (SMS used for treating cardiovascular diseases, such as chronic heart failure. However, its chemical composition has not been fully elucidated, particularly for the preparation derived from Ophiopogon japonicus. This study aimed to establish a systematic and reliable method to quickly and simultaneously analyze the chemical constituents in YQFM by ultra-fast liquid chromatography coupled with ion trap time-of-flight mass spectrometry (UFLC-IT-TOF/MS. Sixty-five compounds in YQFM were tentatively identified by comparison with reference substances or literature data. Furthermore, twenty-one compounds, including three ophiopogonins, fifteen ginsenosides and three lignans were quantified by UFLC-IT-TOF/MS. Notably, this is the first determination of steroidal saponins from O. japonicus in YQFM. The relative standard deviations (RSDs of intra- and inter-day precision, reproducibility and stability were <4.9% and all analytes showed good linearity (R2 ≥ 0.9952 and acceptable recovery of 91.8%–104.2% (RSD ≤ 5.4%, indicating that the methods were reliable. These methods were successfully applied to quantitative analysis of ten batches of YQFM. The developed approach can provide useful and comprehensive information for quality control, further mechanistic studies in vivo and clinical application of YQFM.

  9. Unstable Electrostatic Ion Cyclotron Waves Exited by an Ion Beam

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1976-01-01

    Electrostatic ion cyclotron waves were observed in a quiescent cesium plasma into which a low‐energy beam of sodium ions was injected. The instability appeared when the beam velocity was above 12 times the ion thermal velocity. The waves propagated along the magnetic field with a velocity somewhat...

  10. Theoretical investigation of external injection schemes for laser wakefield acceleration

    NARCIS (Netherlands)

    Luttikhof, Mark Jan Hendrik

    2010-01-01

    This thesis reports on laser wakefield acceleration, a radically new approach for particle acceleration that builds on the huge electric fields that a plasma wave can provide. In this approach, an ultra-short laser pulse of high intensity is sent through a plasma. At sufficient intensity, the radiat

  11. External radiation surveillance

    Energy Technology Data Exchange (ETDEWEB)

    Antonio, E.J.

    1995-06-01

    This section of the 1994 Hanford Site Environmental Report describes how external radiation was measured, how surveys were performed, and the results of these measurements and surveys. External radiation exposure rates were measured at locations on and off the Hanford Site using thermoluminescent dosimeters (TLD). External radiation and contamination surveys were also performed with portable radiation survey instruments at locations on and around the Hanford Site.

  12. Coupling sequential injection on-line preconcentration by means of a renewable microcolumn with ion-exchange beads with detection by electrothermal atomic absorption spectrometry. Comparing the performance of eluting the loaded beads with transporting them directly into the graphite tube

    DEFF Research Database (Denmark)

    Wang, Jianhua; Hansen, Elo Harald

    2001-01-01

    The design of a flow injection/sequential injection (FIA/SIA) on-line preconcentration system incorporating a renewable microcolumn with ion-exchange beads and interfaced with an electrothermal atomic absorption spectrometry (ETAAS) detector is described, and its practical applicability is demons......The design of a flow injection/sequential injection (FIA/SIA) on-line preconcentration system incorporating a renewable microcolumn with ion-exchange beads and interfaced with an electrothermal atomic absorption spectrometry (ETAAS) detector is described, and its practical applicability.......4% for the procedure in which the loaded beads are transported directly to the graphite furnace for pyrolysis and atomization, and even improved in comparison to the traditional unidirectional and bidirectional repetitive elution procedures which under comparable conditions yield R.S.D.-values of 5.8 and 4.......1 and a detection limit of 10.2ng/l along with a sampling frequency of 12 s/h were obtained, which are at the same levels as those for the previously described procedure without elution. The present approach was validated by determination of the nickel contents in two certified reference materials, an industrial...

  13. 局部注射BDNF对压力性尿失禁模型大鼠LPP及EUS内BDNF的影响%The Effect of Local Injection of Brain-derived Neurotrophic Factor on LPP and BDNF in External Urethral Sphincter in Stress Urinary Incontinence Model Rats

    Institute of Scientific and Technical Information of China (English)

    马翠; 王志莲; 郝敏

    2014-01-01

    目的:探究阴部神经(PN)损伤后局部注入脑源性神经营养因子(BDNF)对压力性尿失禁模型大鼠漏尿点压力(LPP)及尿道外括约肌(EUS)脑源性神经营养因子表达的影响。方法:SD大鼠接受模拟分娩损伤和双侧卵巢切除,并建立压力性尿失禁模型。2周后评估模型建立是否成功。造模成功后,大鼠按照随机数字表法分为三组:BDNF组,损伤PN后局部注入BDNF,缝合后标记部位,第4、6、8天分别于标记部位再次注射;生理盐水组,损伤PN后局部注入生理盐水,量及方法同上;假损伤组,分离PN未损伤。2周后再次进行漏尿点压力及喷嚏实验。随后处死大鼠,取EUS行免疫组化,观察BDNF表达变化。结果:PN损伤后,统计学分析显示,生理盐水组LPP明显低于BDNF组和假损伤组,差异均有统计学意义(P0.05);HE染色显示,生理盐水组与假损伤组相比,肌纤维断裂及横纹肌排列致密程度均明显下降;免疫组化结果显示,假损伤组括约肌内BDNF含量低,与BDNF组及生理盐水组比较差异均有统计学意义(P0.05)。结论:局部注射脑源性神经营养因子可能通过刺激神经再生从而促进尿道外括约肌的恢复,进而有利于压力性尿失禁大鼠LPP的恢复。%Objective:To investigate the effect of local injection of brain-derived neurotrophic factor(BDNF) on LPP and BDNF expression in external urethral sphincter(EUS)in stress urinary incontinence model rats after pudendal nerve(PN)injury.Method:SD rats received simulated birth trauma and bilateral ovariectomy,stress urinary incontinence model was established.After 2 weeks,we assessed the model success or not.After the success of modeling, the rats were randomly divided into three groups:the BDNF group,BDNF was local injected after PN injury,position were marked after suture,4,6,8 days the position were injected again;the saline group

  14. Charge breeding of radioactive ions with EBIS and EBIT

    CERN Document Server

    Wenander, Fredrik

    2010-01-01

    A charge state breeder, which transforms externally injected singly charged ions to a higher charge state q+, is an important tool which has applications within atomic, nuclear and even particle physics. The charge breeding concept of radioactive ions has already been demonstrated at REX-ISOLDE/CERN with the use of an Electron beam Ion Source (EBIS) and at several facilities employing Electron Resonance Cyclotron Ion Sources (ECRIS). As will be demonstrated in this paper, EBIS and Electron Beam Ion Traps (EBIT), are well suited for the task as they are capable of delivering clean, highly charged beams within a short transformation time. The increasing demand for highly charged ions of all kind of elements and isotopes, stable and radioactive, to be used for low-energy experiments such as TITAN at TRIUMF and MATS at FAIR, but also for post-acceleration to higher energies, is now pushing the development of the breeders. The next challenge will be to satisfy the needs, for example space-charge capacity, of the s...

  15. Three dimensional analysis of the pore space in fine-grained Boom Clay, using BIB-SEM (broad-ion beam scanning electron microscopy), combined with FIB (focused ion-beam) serial cross-sectioning, pore network modeling and Wood's metal injection

    Science.gov (United States)

    Hemes, Susanne; Klaver, Jop; Desbois, Guillaume; Urai, Janos

    2014-05-01

    The Boom Clay is, besides the Ypresian clays, one of the potential host rock materials for radioactive waste disposal in Belgium (Gens et al., 2003; Van Marcke & Laenen, 2005; Verhoef et al., 2011). To access parameters, which are relevant for the diffusion controlled transport of radionuclides in the material, such as porosity, pore connectivity and permeability, it is crucial to characterize the pore space at high resolution (nm-scale) and in 3D. Focused-ion-beam (FIB) serial cross-sectioning in combination with high resolution scanning electron microscopy (SEM), pore network modeling, Wood's metal injection and broad-ion-beam (BIB) milling, constitute a superior set of methods to characterize the 3D pore space in fine-grained, clayey materials, down to the nm-scale resolution. In the present study, we identified characteristic 3D pore space morphologies, determined the 3D volume porosity of the material and applied pore network extraction modeling (Dong and Blunt, 2009), to access the connectivity of the pore space and to discriminate between pore bodies and pore throats. Moreover, we used Wood's metal injection (WMI) in combination with BIB-SEM imaging to assess the pore connectivity at a larger scale and even higher resolution. The FIB-SEM results show a highly (~ 90 %) interconnected pore space in Boom Clay, down to the resolution of ~ 3E+03 nm³ (voxel-size), with a total volume porosity of ~ 20 %. Pore morphologies of large (> 5E+08 nm³), highly interconnected pores are complex, with high surface area to volume ratios (shape factors G ~ 0.01), whereas small (BIB-SEM, down to a resolution of ~ 50 nm² pixel-size, indicates an interconnected porosity fraction of ~ 80 %, of a total measured 2D porosity of ~ 20 %. Determining and distinguishing between pore bodies and pore throats enables us to compare 3D FIB-SEM pore-size distributions to 2D BIB-SEM data, as well as MIP data. Results show a good agreement between the 2D BIB-SEM and 3D FIB-SEM inferred pore

  16. Uniform H(-) ion beam extraction in a large negative ion source with a tent-shaped magnetic filter.

    Science.gov (United States)

    Tobari, H; Hanada, M; Kashiwagi, M; Taniguchi, M; Umeda, N; Watanabe, K; Inoue, T; Sakamoto, K; Takado, N

    2008-02-01

    Based on previous studies on the spatial uniformity of the negative ion beam, the external magnetic filter was replaced to a novel tent-shaped magnetic filter in the JAEA 10 A negative ion source. The line-cusp field configuration on the source chamber was also changed to form a symmetric magnetic field like many of positive ion sources aiming at high proton yield. This magnetic field configuration allows fast electrons emitted from filament cathodes to rotate azimuthally inside the source chamber. The source configuration thus prevents localization of fast electrons due to their B x grad B drift in the filter field. As a result, the H(-) ion beam profile extracted from a wide region of 340 x 170 mm(2) showed reduction of standard deviation from 16% in the original to 7.9% with the tent filter. The negative ion source with the tent filter satisfied the requirement of the beam uniformity for a large negative ion source in the ITER neutral beam injection.

  17. Externally Verifiable Oblivious RAM

    Directory of Open Access Journals (Sweden)

    Gancher Joshua

    2017-04-01

    Full Text Available We present the idea of externally verifiable oblivious RAM (ORAM. Our goal is to allow a client and server carrying out an ORAM protocol to have disputes adjudicated by a third party, allowing for the enforcement of penalties against an unreliable or malicious server. We give a security definition that guarantees protection not only against a malicious server but also against a client making false accusations. We then give modifications of the Path ORAM [15] and Ring ORAM [9] protocols that meet this security definition. These protocols both have the same asymptotic runtimes as the semi-honest original versions and require the external verifier to be involved only when the client or server deviates from the protocol. Finally, we implement externally verified ORAM, along with an automated cryptocurrency contract to use as the external verifier.

  18. External Beam Therapy (EBT)

    Science.gov (United States)

    ... Esophageal Cancer Treatment Head and Neck Cancer Treatment Lung Cancer Treatment Prostate Cancer Treatment Brain Tumor Treatment Why is ... Radiation Oncology) Breast Cancer Treatment Esophageal Cancer Treatment Lung Cancer Treatment Images related to External Beam Therapy (EBT) Sponsored ...

  19. MALIGNANT EXTERNAL OTITIS

    OpenAIRE

    Massoud Moghaddam

    1993-01-01

    Two case reports of malignant external otitis in the elderly diabetics and their complications and management with regard to our experience at Amir Alam Hospital, Department of ENT will be discussed here.

  20. Checklists for external validity

    DEFF Research Database (Denmark)

    Dyrvig, Anne-Kirstine; Kidholm, Kristian; Gerke, Oke;

    2014-01-01

    RATIONALE, AIMS AND OBJECTIVES: The quality of the current literature on external validity varies considerably. An improved checklist with validated items on external validity would aid decision-makers in judging similarities among circumstances when transferring evidence from a study setting...... to an implementation setting. In this paper, currently available checklists on external validity are identified, assessed and used as a basis for proposing a new improved instrument. METHOD: A systematic literature review was carried out in Pubmed, Embase and Cinahl on English-language papers without time restrictions....... The retrieved checklist items were assessed for (i) the methodology used in primary literature, justifying inclusion of each item; and (ii) the number of times each item appeared in checklists. RESULTS: Fifteen papers were identified, presenting a total of 21 checklists for external validity, yielding a total...

  1. 丹参注射液联合侧脑室外引流救治急性重型原发性颅脑损伤临床观察%Clinical observation of Danshen Injections combined with lateral ventricle external drainage in the treatment of acute severe primary craniocerebral injury

    Institute of Scientific and Technical Information of China (English)

    杜海平; 崔艳杰

    2015-01-01

    Objective To study the effect of Danshen Injections combined with lateral ventricle external drainage in the treatment of acute severe primary craniocerebral injury .Methods 68 cases of acute severe patients with primary brain injury in our hospital in 2013 July‐2014 July was selected as the research objects ,divided into control group and observation group .The control group were given Danshen Injections treatment ,while the observation group were treated by Danshen Injections combined with lateral cerebral ventricular drainage treatment .1 week later Glasgow coma score (GCS) ,clinical curative effect and hematoma removal time were statistically analyzed and compared .Results Before treatment ,no significant difference was observed between the 2 groups .3 days after treatment ,GCS of the observation group of GSC score was significantly higher than the control group .And 1 week after the optimal effect ;the total effective rate of treatment were 70 .59% and 88 .24% for the control group and the observation group .The observation group was obviously higher than that of the control group ,with significant difference (P<0 .05);The mean elimina‐ting times were 10 .0 ± 4 .5 and 4 .0 ± 2 .5 d for the control group and the observation group with significant difference (P<0 .05) . Conclusion Danshen Injections combined with lateral ventricle external drainage in the treatment of acute severe patients with pri‐mary brain injury can improve the patient's total efficiency ,shorten the time of patients with persistent coma ,improve the prognosis of patients and the quality of life .%目的:探讨丹参注射液联合侧脑室外引流救治急性重型原发性颅脑损伤的效果。方法选取我院2013年7月~2014年7月的68例急性重型原发性颅脑损伤患者为研究对象,将其随机分为对照组和观察组。对照组患者使用丹参注射液进行治疗,观察组患者采用丹参注射液联合侧脑室外引流进行治疗。观察2组

  2. Migration with fiscal externalities.

    Science.gov (United States)

    Hercowitz, Z; Pines, D

    1991-11-01

    "This paper analyses the distribution of a country's population among regions when migration involves fiscal externalities. The main question addressed is whether a decentralized decision making [by] regional governments can produce an optimal population distribution...or a centralized intervention is indispensable, as argued before in the literature.... It turns out that, while with costless mobility the fiscal externality is fully internalized by voluntary interregional transfers, with costly mobility, centrally coordinated transfers still remain indispensable for achieving the socially optimal allocation."

  3. Sen cycles and externalities

    OpenAIRE

    Piggins, Ashley; Salerno, Gillian

    2016-01-01

    It has long been understood that externalities of some kind are responsible for Sen’s (1970) theorem on the impossibility of a Paretian liberal. However, Saari and Petron (2006) show that for any social preference cycle generated by combining the weak Pareto principle and individual decisiveness, every decisive individual must suffer at least one strong negative externality. We show that this fundamental result only holds when individual preferences are strict. Building on their contribution,...

  4. 离子色谱法同时测定中药注射剂中亚硫酸盐及枸橼酸含量的研究%Simultaneous determination of sulfite and citric acid in chinese medicine injection by ion chromatography

    Institute of Scientific and Technical Information of China (English)

    王欣美; 毛秀红; 王柯

    2012-01-01

    Objective; An ion chromatographic method was developed to analyze sulfite and citric acid in Chinese medicine injections. Methods; The injection samples were diluted and cleaned by Onguard II RP column before injection. AS11 - HC chromatographic column was used and the mobile phase was 12 mmol/L ~ 60 mmol/L KOH. The ions were detected by suppressed conductivity detector. Results; The calibration curves of sulfite and citric acid were both in good linearity within the range from 0 μg to 200 μg (r = 0. 9998, 0.9999). The detection limits were 0.014 mg/ml for sulfite and 0.013 mg/ml for citric acid. The average recoveries were between 90% ~ 105% , and relative standard deviation (RSD) was <5%. Conclusion: The method is simple, accurate and sensitive, which is applicable to the testing of large quantity batches of Chinese medicine injection.%目的:建立中药注射剂中的亚硫酸钠和枸橼酸测定方法.方法:样品稀释后经Onguard Ⅱ RP小柱净化后进样.选用IonPac AS11 - HC阴离子分析柱,12 mmol/L~ 60 mmol/L KOH淋洗液,电导检测器.结果:亚硫酸钠和枸橼酸在0 μg~ 200 μg范围内线性关系良好,相关系数分别为0.9998和0.9999,检测限分别为0.014 mg/ml和0.013 mg/ml,回收率为90% ~ 105%,RSD均小于5%.结论:本方法操作简便、准确、灵敏,适用于大批样品的检测.

  5. Penicillin G Procaine Injection

    Science.gov (United States)

    Penicillin G procaine injection is used to treat certain infections caused by bacteria. Penicillin G procaine injection should not be used to treat ... in the treatment of certain serious infections. Penicillin G procaine injection is in a class of medications ...

  6. A CW radiofrequency ion source for production of negative hydrogen ion beams for cyclotrons

    Energy Technology Data Exchange (ETDEWEB)

    Kalvas, T.; Tarvainen, O.; Komppula, J.; Koivisto, H.; Tuunanen, J. [University of Jyväskylä, Department of Physics (Finland); Potkins, D.; Stewart, T.; Dehnel, M. P. [D-Pace, Inc., Nelson, B.C. Canada (Canada)

    2015-04-08

    A CW 13.56 MHz radiofrequency-driven ion source RADIS for production of H{sup −} and D{sup −} beams is under development for replacing the filament-driven ion source of the MCC30/15 cyclotron. The RF ion source has a 16-pole multicusp plasma chamber, an electromagnet-based magnetic filter and an external planar spiral RF antenna behind an AlN window. The extraction is a 5-electrode system with an adjustable puller electrode voltage for optimizing the beam formation, a water-cooled electron dump electrode and an accelerating einzel lens. At 2650 W of RF power, the source produces 1 mA of H{sup −} (2.6 mA/cm{sup 2}), which is the intensity needed at injection for production of 200 µA H{sup +} with the filament-driven ion source. A simple pepperpot device has been developed for characterizing the beam emittance. Plans for improving the power efficiency with the use of a new permanent magnet front plate is discussed.

  7. Iron Dextran Injection

    Science.gov (United States)

    ... allergic to iron dextran injection; any other iron injections such as ferric carboxymaltose (Injectafer), ferumoxytol (Feraheme), iron sucrose (Venofer), or sodium ferric gluconate (Ferrlecit);any other ...

  8. Atomic excitation and recombination in external fields

    Energy Technology Data Exchange (ETDEWEB)

    Nayfeh, M.H.; Clark, C.W.

    1985-01-01

    This volume offers a timely look at Rydberg states of atoms in external fields and dielectronic recombination. Each topic provides authoritative coverage, presents a fresh account of a flourishing field of current atomic physics and introduces new opportunities for discovery and development. Topics considered include electron-atom scattering in external fields; observations of regular and irregular motion as exemplified by the quadratic zeeman effect and other systems; Rydberg atoms in external fields and the Coulomb geometry; crossed-field effects in the absorption spectrum of lithium in a magnetic field; precise studies of static electric field ionization; widths and shapes of stark resonances in sodium above the saddle point; studies of electric field effects and barium autoionizing resonances; autoionization and dielectronic recombination in plasma electric microfields; dielectronic recombination measurements on multicharged ions; merged beam studies of dielectronic recombination; Rydberg atoms and dielectronic recombination in astrophysics; and observations on dielectronic recombination.

  9. Amplification of an electromagnetic field at the scattering of the nonrelativistic electron by an ion in the external field of medium intensity for an arbitrary angle of the initial electron

    Science.gov (United States)

    Tsybul'nik, V. A.; Roshchupkin, S. P.

    2014-08-01

    We theoretically study the gain coefficient for a electromagnetic field, in the scattering of nonrelativistic electrons by ions in a elliptically polarized light wave. We obtain a simple analytical expression for a field amplification constant in logarithmic approach to an arbitrary angle of the initial electron. The formula supplements and extends the domain of applicability of the known Marcuse formula for the linear polarization in the presence of a weak field. It is demonstrated that the maximum gain is reached when the initial electron velocity directs along the major semi-axis of the polarization ellipse. In the range of optical frequencies, the gain coefficient of the laser radiation can be significant for relatively high powers of electron beams. Obtained results may be experimentally verified, for example, by the scientific facilities at the SLAC National Accelerator Laboratory and FAIR (Facility for Antiproton and Ion Research, Darmstadt, Germany).

  10. Miniaturized Ion Mobility Spectrometer

    Science.gov (United States)

    Kaye, William J. (Inventor); Stimac, Robert M. (Inventor)

    2015-01-01

    By utilizing the combination of a unique electronic ion injection control circuit in conjunction with a particularly designed drift cell construction, the instantly disclosed ion mobility spectrometer achieves increased levels of sensitivity, while achieving significant reductions in size and weight. The instant IMS is of a much simpler and easy to manufacture design, rugged and hermetically sealed, capable of operation at high temperatures to at least 250.degree. C., and is uniquely sensitive, particularly to explosive chemicals.

  11. The ATLAS positive ion injector

    Energy Technology Data Exchange (ETDEWEB)

    Shepard, K.W.; Bollinger, L.M.; Pardo, R.C.

    1990-01-01

    This paper reviews the design, construction status, and beam tests to date of the positive ion injector (PII) which is replacing the tandem injector for the ATLAS heavy-ion facility. PII consists of an ECR ion source on a 350 KV platform injecting a very low velocity superconducting linac. The linac is composed of an independently-phased array of superconducting four-gap interdigital resonators which accelerate over a velocity range of .006 to .05c. In finished form, PII will be able to inject ions as heavy as uranium into the existing ATLAS linac. Although at the present time little more than 50% of the linac is operational, the indenpently-phased array is sufficiently flexible that ions in the lower half of the periodic table can be accelerated and injected into ATLAS. Results of recent operational experience will be discussed. 5 refs.

  12. Environmental external effects from wind power based on the EU ExternE methodology

    DEFF Research Database (Denmark)

    Ibsen, Liselotte Schleisner; Nielsen, Per Sieverts

    1998-01-01

    The European Commission has launched a major study project, ExternE, to develop a methodology to quantify externalities. A “National Implementation Phase”, was started under the Joule II programme with the purpose of implementing the ExternE methodology in all member states. The main objective...

  13. Electron bunch injection at an angle into a laser wakefield

    NARCIS (Netherlands)

    Luttikhof, M.J.H.; Khachatryan, A.G.; van Goor, F.A.; Boller, Klaus J.; Mora, P.

    2009-01-01

    External injection of electron bunches longer than the plasma wavelength in a laser wakefield accelerator can lead to the generation of femtosecond ultra relativistic bunches with a couple of percent energy spread. Extensive study has been done on external electron bunch (e.g., one generated by a

  14. Clinical observation of diabetic foot ulcer treated with Shuxuetong plus external application of deproteinised ;calf blood serum injection%疏血通注射液联合外敷小牛血清去蛋白提取物治疗糖尿病足溃疡的临床观察

    Institute of Scientific and Technical Information of China (English)

    王慧卿; 王桂英; 尉杰忠

    2016-01-01

    目的:评价疏血通注射液联合外用小牛血清去蛋白提取物治疗糖尿病足溃疡的临床疗效。方法选择糖尿病足溃疡患者60例,采用随机数字表法分为两组,治疗组30例外用小牛血清血去蛋白提取物联合静脉滴注疏血通注射液;对照组30例给予常规西药治疗。1个月为1个疗程。两组均采用胰岛素控制血糖,抗生素控制感染,足部溃疡局部清创引流、坏死组织清除等治疗。结果治疗组总有效率显著高于对照组(86.7%比60.0%,χ2=5.455,P =0.020)。肉芽组织出现时间[(6.60±1.14)d 比(10.80±2.17)d,t =-3.834,P =0.008],创面愈合时间[(23.62±6.14)d 比(35.65±4.45)d,t =-4.405,P =0.002]较对照组明显缩短,两组治疗后创面面积均明显缩小,但治疗组更明显[(3.48±1.16)cm2比(8.60±2.51)cm2,t =-4.143,P =0.007]。结论疏血通注射液联合外敷小牛血清去蛋白提取物治疗糖尿病足溃疡疗效优于常规西药治疗。%Objective To evaluate the clinical effect of Shuxuetong plus external application of deproteinised calf blood serum injection on diabetic ulcer foot.Methods 60 patients with diabetic foot ulcer were enrolled:30 cases (treatment group)were randomly assigned to receive deproteinised calf blood serum injection(external use)plus Shuxuetong(iv gtt),and the other 30 cases (control group)received routine western medicine therapy.One course of treatment lasted one month.In addition,both two groups received insulin to control blood sugar and antibiotics to control infection,with foot ulcer treated with debridement,drainage,and removal of necrotic tissue etc.Results Com-pared with the control group,the effective rate was higher in the treatment group(86.7% vs.60.0%,χ2 =5.455,P =0.020).The occurrence time of granulation tissue[(6.60 ±1.14)d vs.(10.80 ±2.17)d,t =-3.834,P =0.008] and wound

  15. Externality or sustainability economics?

    Energy Technology Data Exchange (ETDEWEB)

    Bergh, Jeroen C.J.M. van den [ICREA, Barcelona (Spain); Department of Economics and Economic History and Institute for Environmental Science and Technology, Universitat Autonoma de Barcelona (Spain)

    2010-09-15

    In an effort to develop 'sustainability economics' Baumgaertner and Quaas (2010) neglect the central concept of environmental economics-'environmental externality'. This note proposes a possible connection between the concepts of environmental externality and sustainability. In addition, attention is asked for other aspects of 'sustainability economics', namely the distinction weak/strong sustainability, spatial sustainability and sustainable trade, distinctive sustainability policy, and the ideas of early 'sustainability economists'. I argue that both sustainability and externalities reflect a systems perspective and propose that effective sustainability solutions require that more attention is given to system feedbacks, notably other-regarding preferences and social interactions, and energy and environmental rebound. The case of climate change and policy is used to illustrate particular statements. As a conclusion, a list of 20 insights and suggestions for research is offered. (author)

  16. Metasurface external cavity laser

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Luyao, E-mail: luyaoxu.ee@ucla.edu; Curwen, Christopher A.; Williams, Benjamin S. [Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States); California NanoSystems Institute, University of California, Los Angeles, California 90095 (United States); Hon, Philip W. C.; Itoh, Tatsuo [Department of Electrical Engineering, University of California, Los Angeles, California 90095 (United States); Chen, Qi-Sheng [Northrop Grumman Aerospace Systems, Redondo Beach, California 90278 (United States)

    2015-11-30

    A vertical-external-cavity surface-emitting-laser is demonstrated in the terahertz range, which is based upon an amplifying metasurface reflector composed of a sub-wavelength array of antenna-coupled quantum-cascade sub-cavities. Lasing is possible when the metasurface reflector is placed into a low-loss external cavity such that the external cavity—not the sub-cavities—determines the beam properties. A near-Gaussian beam of 4.3° × 5.1° divergence is observed and an output power level >5 mW is achieved. The polarized response of the metasurface allows the use of a wire-grid polarizer as an output coupler that is continuously tunable.

  17. The first experimental results on laser ion loading into superconducting ECR ion source at RIKEN

    CERN Document Server

    Arzumanyan, G M; Shirkov, G D; Yano, Y

    2002-01-01

    The first experimental results on ions and neutrals injection by means of laser ablation from metal targets into the RIKEN 18 GHz superconducting electron cyclotron resonance ion source (SC ECRIS) are presented. Pulsed aluminium ion currents up to Al sup 8 sup + were generated in the source. The difference in pulse shapes of various charge states of the extracted ion currents is registered

  18. Sipuleucel-T Injection

    Science.gov (United States)

    Sipuleucel-T injection is used to treat certain types of advanced prostate cancer. Sipuleucel-T injection is in a class of medications called ... Sipuleucel-T injection comes as a suspension (liquid) to be injected over about 60 minutes into a vein ...

  19. Verification of the computer code ATHLET in the framework of the external verification group ATHLET BETHSY test 9.3 - steam generator U-tube rupture with failure of the high pressure injection. Final report; Verifikation des ATHLET-Rechenprogramms im Rahmen der externen Verifikationsgruppe ATHLET BETHSY Test 9.3 - Heizrohrbruch mit Versagen der Hochdruck-Noteinspeisung. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Krepper, E.; Schaefer, F. [Forschungszentrum Rossendorf e.V. (FZR) (Germany). Inst. fuer Sicherheitsforschung

    1998-08-01

    In the framework of the external validation of the thermalhydraulic code ATHLET MOD 1.1 CYCLE D, which is being developed by the GRS, post test analyses of two experiments were done, which were performed at the French integral test facility BETHSY. During test 9.3 the consequences of a steam generator U-tube rupture with failure of the high pressure injection and of the auxiliary feedwater supply were investigated. As accident management measures, the depressurization of the secondary sides, first of the two intact steam generators, then of the damaged steam generator and finally the primary depressurization by opening of the pressurizer valve were performed. The results show, that the code ATHLET is able to describe the complex scenario in good accordance with the experiment. The safety relevant statement could be reproduced. Deviations, which did not impose the general results, occurred concerning the break mass flow during the depressurization of the damaged steam generator and the description of the failure of the heat transfer to the damaged steam generator. Reasons are hardly to find, because these processes are highly complex. (orig.) [Deutsch] Im Rahmen der externen Validierung des von der Gesellschaft fuer Anlagen- und Reaktorsicherheit entwickelten Stoerfallcodes ATHLET, der in der Version Mod 1.1 Cycle D vorlag, wurden zwei Experimente nachgerechnet und analysiert, die an der franzoesischen Versuchsanlage BETHSY durchgefuehrt wurden. Im Test 9.3 werden die Konsequenzen untersucht, wenn bei einem Heizrohrbruch die Hochdruckeinspeisung sowie die Not-Speisewasserversorgung der Dampferzeuger versagen und nur die Druckspeicher sowie die Niederdruckeinspeisung zur Verfuegung stehen. Als Accident Management Massnahmen wurde die sekundaere Druckentlastung und schliesslich die primaere Entlastung ueber den Druckhalter untersucht. Die Analyse kommt zu dem Ergebnis, dass der Code ATHLET in der Lage ist, dieses komplexe Szenario recht gut zu beschreiben. Die

  20. Clinical observation on the efficacy of local injection of anesthetic and corticosteroid combined with rehabilitation training in treatment of patients with external humeral epicondylitis%局部注射麻醉药及皮质类固醇复合康复训练治疗肱骨外上髁炎的临床观察

    Institute of Scientific and Technical Information of China (English)

    李德刚; 李彦平; 罗克金

    2016-01-01

    目的:观察局部注射麻醉药及皮质类固醇复合康复训练治疗肱骨外上髁炎的临床效果。方法选择40例疼痛时间在1~4周的肱骨外上髁炎患者,随机分成局部注射组(B 组,n =20)和局部注射复合康复训练组(BR 组,n=20)。B 组仅接受肱骨外上髁0.5%利多卡因+甲强龙20 mg 注射治疗(1次/周,共2周)治疗。BR 组接受肱骨外上髁同样药物注射治疗(1次/周,共2周)复合康复训练(3次/天,5分钟/次,共2周)治疗。观察两组治疗后第1、2、4、8周的局部疼痛感、局部压痛、屈肘负重的疼痛视觉模拟评分。观察两组治疗后4周和8周时疼痛症状复发率。结果两组治疗后第1周和第2周时疼痛程度较治疗前显著降低( P 0.05)。治疗后第4周和第8周时 BR 组疼痛程度明显低于 B 组( P 0. 05). The intensity of pain in patients of group BR in 4 and 8 weeks after treatment was significantly lower than that of patients in group B( P < 0. 05). The recurrence rates of LA,LPP,and EFWBP at 4 and 8 weeks after the treatment in group BR were significantly lower than those in group B( P < 0. 05). Conclusion Local injection of anesthethetic combined with rehabilitation training is effective in controlling the local pain,improving the movement and keeping a long - term stable therapeutic effect in patients with external hu-meral epicondylitis.

  1. Laser ion source studies at CERN

    CERN Document Server

    Tambini, J

    1995-01-01

    The plasma produced when a powerful laser pulse is focused onto a target surface in vacuum can provide a copious source of highly charged ions. Ions can then be extracted from the plasma to form a high current, short pulse length ion beam. Experimental laser ion sources have been the subject of investigation in medical physics and particle accelerator applications; a laser ion source is an option for the injection system of heavy ions for the Large Hadron Collider at CERN where a high intensity lead ion beam is required. This paper describes work carried out at CERN to develop a CO2 laser ion source.

  2. Stochastic Control - External Models

    DEFF Research Database (Denmark)

    Poulsen, Niels Kjølstad

    2005-01-01

    This note is devoted to control of stochastic systems described in discrete time. We are concerned with external descriptions or transfer function model, where we have a dynamic model for the input output relation only (i.e.. no direct internal information). The methods are based on LTI systems...

  3. Productivity Change and Externalities

    DEFF Research Database (Denmark)

    Kravtsova, Victoria

    2014-01-01

    firms and the economy as a whole. The approach used in the current research accounts for different internal as well as external factors that individual firms face and evaluates the effect on changes in productivity, technology as well as the efficiency of domestic firms. The empirical analysis focuses...... change in different types of firms and sectors of the economy...

  4. Multiple external root resorption.

    Science.gov (United States)

    Yusof, W Z; Ghazali, M N

    1989-04-01

    Presented is an unusual case of multiple external root resorption. Although the cause of this resorption was not determined, several possibilities are presented. Trauma from occlusion, periodontal and pulpal inflammation, and resorption of idiopathic origin are all discussed as possible causes.

  5. Injection and extraction for cyclotrons

    CERN Document Server

    Kleeven, W

    2006-01-01

    The main design goals for beam injection are explained and special problems related to a central region with internal ion source are considered. The principle of a PIG source is addressed. The issue of vertical focusing in the cyclotron centre is briefly discussed. Several examples of numerical simulations are given. Different ways of (axial) injection are briefly outlined. A proposal for a magnetostatic axial inflector is given. Different solutions for beam extraction are treated. These include the internal target, extraction by stripping, resonant extraction using a deflector and self-extraction. The different ways of creating a turn-separation are explained. The purpose of different types of extraction devices such as harmonic coils, deflectors and gradient corrector channels are outlined. Several illustrations are given in the form of photographs and drawings.

  6. RF H-minus ion source development in China spallation neutron source

    Science.gov (United States)

    Chen, W.; Ouyang, H.; Xiao, Y.; Liu, S.; Lü, Y.; Cao, X.; Huang, T.; Xue, K.

    2017-08-01

    China Spallation Neutron Source (CSNS) phase-I project currently uses a Penning surface plasma H- ion source, which has a life time of several weeks with occasional sparks between high voltage electrodes. To extend the life time of the ion source and prepare for the CSNS phase-II, we are trying to develop a RF negative hydrogen ion source with external antenna. The configuration of the source is similar to the DESY external antenna ion source and SNS ion source. However several changes are made to improve the stability and the life time. Firstly, Si3N4 ceramic with high thermal shock resistance, and high thermal conductivity is used for plasma chamber, which can endure an average power of 2000W. Secondly, the water-cooled antenna is brazed on the chamber to improve the energy efficiency. Thirdly, cesium is injected directly to the plasma chamber if necessary, to simplify the design of the converter and the extraction. Area of stainless steel exposed to plasma is minimized to reduce the sputtering and degassing. Instead Mo, Ta, and Pt coated materials are used to face the plasma, which makes the self-cleaning of the source possible.

  7. On Maximal Injectivity

    Institute of Scientific and Technical Information of China (English)

    Ming Yi WANG; Guo ZHAO

    2005-01-01

    A right R-module E over a ring R is said to be maximally injective in case for any maximal right ideal m of R, every R-homomorphism f : m → E can be extended to an R-homomorphism f' : R → E. In this paper, we first construct an example to show that maximal injectivity is a proper generalization of injectivity. Then we prove that any right R-module over a left perfect ring R is maximally injective if and only if it is injective. We also give a partial affirmative answer to Faith's conjecture by further investigating the property of maximally injective rings. Finally, we get an approximation to Faith's conjecture, which asserts that every injective right R-module over any left perfect right self-injective ring R is the injective hull of a projective submodule.

  8. Nanostructuring steel for injection molding tools

    DEFF Research Database (Denmark)

    Al-Azawi, A.; Smistrup, Kristian; Kristensen, Anders

    2014-01-01

    and ion beam etching are combined to nanostructure the planar surface of a steel wafer. Injection molded plastic parts with enhanced surface properties, like anti-reflective, superhydrophobic and structural colors can be achieved by micro-and nanostructuring the surface of the steel molds. We investigate...

  9. External Approach Microsurgery of Retinal Dialysis

    Institute of Scientific and Technical Information of China (English)

    Ying Zhang; Piqing Hu; Lixin Shun; Xuechun Zhu; Yingwu Yi; Wen Liu

    2005-01-01

    Purpose: To explore the effect of external approach microsurgery in retinal dialysis.Methods: Consecutive 30 eyes of 28 patients with retinal dialysis were enrolled for this study. The progresses of the external approach microsurgery were following. Under the surgical microscopy, the preplacement of mattress sutures for buckling and/or encircling following retrobulbar anesthesia and scleral exposure, draining subretinal fluid, the cryotherapy of retinal breaks, checking the position of breaks on scleral buckle and gases injection were performed in turn.Results: After drainage of subretinal fluid, with scleral depression cryotherapy reaction around breaks could be observed clearly under the microscopy. All breaks were located on anterior slope of the buckle. Intraoperative complications were mild subretinal hemorrhage at drainage site and corneal epithelium exfoliation in 3 eyes, respectively.Postoperative complications were mainly secondary glaucoma and retinal redetachment.The one-operation reattachmentl rate was 96.7% (29 eyes), and the final reattachment rate was 100% after one eye had a second external approach microsurgery. The postoperative vision acuity (VA) was significantly better than the preoperative VA (X2=9.529, P< 0.01).Conclusion: External approach microsurgery has favourable effect on the surgery of retinal dialysis.

  10. ExternE transport methodology for external cost evaluation of air pollution

    DEFF Research Database (Denmark)

    Jensen, S. S.; Berkowicz, R.; Brandt, J.

    The report describes how the human exposure estimates based on NERI's human exposure modelling system (AirGIS) can improve the Danish data used for exposure factors in the ExternE Transport methodology. Initially, a brief description of the ExternE Tranport methodology is given and it is summaris...

  11. The External Mind

    DEFF Research Database (Denmark)

    The External Mind: an Introduction by Riccardo Fusaroli, Claudio Paolucci pp. 3-31 The sign of the Hand: Symbolic Practices and the Extended Mind by Massimiliano Cappuccio, Michael Wheeler pp. 33-55 The Overextended Mind by Shaun Gallagher pp. 57-68 The "External Mind": Semiotics, Pragmatism......, Extended Mind and Distributed Cognition by Claudio Paolucci pp. 69-96 The Social Horizon of Embodied Language and Material Symbols by Riccardo Fusaroli pp. 97-123 Semiotics and Theories of Situated/Distributed Action and Cognition: a Dialogue and Many Intersections by Tommaso Granelli pp. 125-167 Building...... Action in Public Environments with Diverse Semiotic Resources by Charles Goodwin pp. 169-182 How Marking in Dance Constitutes Thinking with the Body by David Kirsh pp. 183-214 Ambiguous Coordination: Collaboration in Informal Science Education Research by Ivan Rosero, Robert Lecusay, Michael Cole pp. 215-240...

  12. External-Memory Multimaps

    CERN Document Server

    Angelino, Elaine; Mitzenmacher, Michael; Thaler, Justin

    2011-01-01

    Many data structures support dictionaries, also known as maps or associative arrays, which store and manage a set of key-value pairs. A \\emph{multimap} is generalization that allows multiple values to be associated with the same key. For example, the inverted file data structure that is used prevalently in the infrastructure supporting search engines is a type of multimap, where words are used as keys and document pointers are used as values. We study the multimap abstract data type and how it can be implemented efficiently online in external memory frameworks, with constant expected I/O performance. The key technique used to achieve our results is a combination of cuckoo hashing using buckets that hold multiple items with a multiqueue implementation to cope with varying numbers of values per key. Our external-memory results are for the standard two-level memory model.

  13. The Research and Development of the External Magnetic Field Acting on Electro-Deposition Process

    OpenAIRE

    Wu Menghua; Jia Weiping

    2016-01-01

    The research and development status of the electro-deposition technology under the action of external magnetic field are introduced. The basic characteristics and applied manners of external magnetic field in electro-deposition process are summarized. The acting principle of external magnetic field, the effects of magnetic hydrodynamics (MHD) caused by the Lorentz force, and the acting of magnetic force on the metal ions and particles are described. The main actions of external magnetic field...

  14. Epoetin Alfa Injection

    Science.gov (United States)

    ... Combivir), a medication used to treat human immunodeficiency virus (HIV). Epoetin alfa injection is also used before ... inject epoetin alfa, as directed by your doctor. Write down the date, time, dose of epoetin alfa ...

  15. Collagenase Clostridium Histolyticum Injection

    Science.gov (United States)

    Collagenase Clostridium histolyticum injection is used to treat Dupuytren's contracture (a painless thickening and tightening of tissue [cord] beneath ... of tissue can be felt upon examination. Collagenase Clostridium histolyticum injection is also used to treat Peyronie's ...

  16. Iron Sucrose Injection

    Science.gov (United States)

    Iron sucrose injection is used treat iron-deficiency anemia (a lower than normal number of red blood cells due ... and may cause the kidneys to stop working). Iron sucrose injection is in a class of medications called iron ...

  17. Intracytoplasmic sperm injection

    Science.gov (United States)

    Intracytoplasmic sperm injection, or ICSI, is a form of in vitro fertilization in which fertilization occurs outside of the ... laboratory dish. Within a few hours, a single sperm is injected through a fine needle into the ...

  18. Sodium Ferric Gluconate Injection

    Science.gov (United States)

    Sodium ferric gluconate injection is used to treat iron-deficiency anemia (a lower than normal number of ... are also receiving the medication epoetin (Epogen, Procrit). Sodium ferric gluconate injection is in a class of ...

  19. Calcitonin Salmon Injection

    Science.gov (United States)

    Calcitonin salmon injection is used to treat osteoporosis in postmenopausal women. Osteoporosis is a disease that causes bones to weaken and break more easily. Calcitonin salmon injection is also used to treat Paget's disease ...

  20. Other Injectable Medications

    Science.gov (United States)

    ... July 17, 2013 Last Edited: February 22, 2017 Articles from Diabetes Forecast® magazine: cg-infusion-sets,meds-bg-injectables,cg-injection-aids, In this section Treatment and Care Medication Insulin & ...

  1. Injection losses and protection

    CERN Document Server

    Bartmann, W; Baudrenghien, P; Bracco, C; Dehning, B; Di Mauro, A; Drosdal, L; Emery, J; Goddard, B; Holzer, E B; Höfle, W; Kain, V; Meddahi, M; Radaelli, S; Shaposhnilova, E; Uythoven, J; Valuch, D; Wenninger, J; Zamantzas, C; Gianfelice-Wendt, E

    2012-01-01

    Injection losses are compared for 2010 and 2011 operation. Mitigation techniques which were put in place in 2010 to reduce losses at injection are described. Issues in 2011 operation, their potential improvements and the performance reach for 2012 are shown.

  2. Bands of ions and angular V's - A conjugate manifestation of ionospheric ion acceleration

    Science.gov (United States)

    Winningham, J. D.; Burch, J. L.; Frahm, R. A.

    1984-01-01

    Data from the hot plasma instruments on Dynamics Explorer 1 and 2 spacecraft have been used to study the injection, drift, and subsequent precipitation of suprathermal positive ions in the auroral zone. The observation at both high and low altitudes of electron inverted 'V' events in the boundary plasma sheet (BPS) and of ion 'bands' (energy decreasing with decreasing latitude) in the adjacent central plasma sheet (CPS) leads to the following ion injection model: upward-moving energetic ion beams are injected onto BPS magnetic field lines by the electrostatic potential drops associated with electron inverted V's. As the ion beams move toward the equator and into the conjugate hemisphere they are convected to lower latitudes and into the CPS. The energy-latitude dependence of the ion bands, coupled with concurrent ion convection measurements, indicate that the ion distributions are primarily O(+), in agreement with their postulated ionospheric source.

  3. Determination of trace metal ions via on-line separation and preconcentration by means of chelating Sepharose beads in a sequential injection lab-on-valve (SI-LOV) system coupled to electrothermal atomic absorption spectrometric detection

    DEFF Research Database (Denmark)

    Long, Xiangbao; Hansen, Elo Harald; Miró, Manuel

    2005-01-01

    The analytical performance of an on-line sequential injection lab-on-valve (SI-LOV) system using chelating Sepharose beads as sorbent material for the determination of ultra trace levels of Cd(II), Pb(II) and Ni(II) by electrothermal atomic absorption spectrometry (ETAAS) is described and discussed...

  4. Beam injection into RHIC

    Energy Technology Data Exchange (ETDEWEB)

    Fischer, W.; Hahn, H.; MacKay, W.W.; Satogata, T.; Tsoupas, N.; Zhang, W.

    1997-07-01

    During the RHIC sextant test in January 1997 beam was injected into a sixth of one of the rings for the first time. The authors describe the injection zone and its bottlenecks. They report on the commissioning of the injection system, on beam based measurements of the kickers and the application program to steer the beam.

  5. Injection moulding antireflective nanostructures

    DEFF Research Database (Denmark)

    Christiansen, Alexander Bruun; Clausen, Jeppe Sandvik; Mortensen, N. Asger

    2014-01-01

    in an injection moulding process, to fabricate the antireflective surfaces. The cycle-time was 35 s. The injection moulded structures had a height of 125 nm, and the visible spectrum reflectance of injection moulded black polypropylene surfaces was reduced from 4.5±0.5% to 2.5±0.5%. The gradient of the refractive...

  6. Injection moulding antireflective nanostructures

    DEFF Research Database (Denmark)

    Christiansen, Alexander Bruun; Clausen, Jeppe Sandvik; Mortensen, N. Asger

    in an injection moulding process, to fabricate the antireflective surfaces. The cycle-time was 35 s. The injection moulded structures had a height of 125 nm, and the visible spectrum reflectance of injection moulded black polypropylene surfaces was reduced from 4.5±0.5% to 2.5±0.5%. The gradient of the refractive...

  7. Optimization of the Multi-turn Injection Efficiency for Medical Synchrotron

    CERN Document Server

    Kim, J; Yoon, M

    2016-01-01

    We present a method for optimization of the multi-turn injection effciency for medical synchrotron. We show that for given injection energy the injection efficiency can be greatly enhanced by choosing transverse tunes appropriately as well as optimizing the injection bump and the number of turns required for beam injection. We verify our study by applying the method to the Korea Heavy Ion Medical Accelerator (KHIMA) synchrotron which is currently built at the campus of Dongnam Institute of Radiological and Medical Sciences (DIRAMS) in Busan, Korea. First the frequency map analysis is performed with the help of ELEGANT and ACCSIM codes. The tunes which yield the good injection efficiency are then selected. With these tunes the injection bump and the number of turns required for injection are then optimized by tracking a number of particles up to one thousand turns after injection beyond which there is no further beam loss. Results for optimization of the injection efficiency for proton ion are presented.

  8. A New Comprehensive Approach for Predicting Injectivity Decline during Waterflooding

    DEFF Research Database (Denmark)

    Yuan, Hao; Nielsen, Sidsel Marie; Shapiro, Alexander

    Injectivity decline during sea waterflooding or produced water re-injection is widely observed in North Sea, Gulf of Mexico and Campos Basin fields. The formation damage occurs mainly due to the deposition of suspended solids around injectors and the build-up the external filter cakes in the well...... injectivity decline during water flooding is proposed. The deep bed filtration is described by novel stochastic random walk equations. The injectivity decline model takes into account the reservoir heterogeneity and the distribution of solid particles by sizes. It also accounts for the later formation...

  9. Quasi-stable injection channels in a wakefield accelerator

    CERN Document Server

    Wiltshire-Turkay, Mara; Pukhov, Alexander

    2016-01-01

    Particle-driven plasma-wakefield acceleration is a promising alternative to conventional electron acceleration techniques, potentially allowing electron acceleration to energies orders of magnitude higher than can currently be achieved. In this work we investigate the dependence of the energy gain on the position at which electrons are injected into the wake. Test particle simulations show previously unobserved complex structure in the parameter space, with quasi-stable injection channels forming for particles injected in narrow regions away from the centre of the wake. The result is relevant to the planning and tuning of experiments making use of external injection.

  10. Memory and Spin Injection Devices Involving Half Metals

    Directory of Open Access Journals (Sweden)

    M. Shaughnessy

    2011-01-01

    Full Text Available We suggest memory and spin injection devices fabricated with half-metallic materials and based on the anomalous Hall effect. Schematic diagrams of the memory chips, in thin film and bulk crystal form, are presented. Spin injection devices made in thin film form are also suggested. These devices do not need any external magnetic field but make use of their own magnetization. Only a gate voltage is needed. The carriers are 100% spin polarized. Memory devices may potentially be smaller, faster, and less volatile than existing ones, and the injection devices may be much smaller and more efficient than existing spin injection devices.

  11. Ion current rectification inversion in conic nanopores: nonequilibrium ion transport biased by ion selectivity and spatial asymmetry.

    Science.gov (United States)

    Yan, Yu; Wang, Lin; Xue, Jianming; Chang, Hsueh-Chia

    2013-01-28

    We show both theoretically and experimentally that the ion-selectivity of a conic nanopore, as defined by a normalized density of the surface charge, significantly affects ion current rectification across the pore. For weakly selective negatively charged pores, intra-pore ion transport controls the current and internal ion enrichment/depletion at positive/reverse biased voltage (current enters/leaves through the tip, respectively), which is responsible for current rectification. For strongly selective negatively charged pores under positive bias, the current can be reduced by external field focusing and concentration depletion at the tip at low ionic strengths and high voltages, respectively. These external phenomena produce a rectification inversion for highly selective pores at high (low) voltage (ionic strength). With an asymptotic analysis of the intra-pore and external ion transport, we derive simple scaling laws to quantitatively capture empirical and numerical data for ion current rectification and rectification inversion of conic nanopores.

  12. Regularization by External Variables

    DEFF Research Database (Denmark)

    Bossolini, Elena; Edwards, R.; Glendinning, P. A.

    2016-01-01

    Regularization was a big topic at the 2016 CRM Intensive Research Program on Advances in Nonsmooth Dynamics. There are many open questions concerning well known kinds of regularization (e.g., by smoothing or hysteresis). Here, we propose a framework for an alternative and important kind of regula...... of regularization, by external variables that shadow either the state or the switch of the original system. The shadow systems are derived from and inspired by various applications in electronic control, predator-prey preference, time delay, and genetic regulation....

  13. Comparisons of Predicted Plasma Performance in ITER H-mode Plasmas with Various Mixes of External He

    Energy Technology Data Exchange (ETDEWEB)

    R.V. Budny

    2009-03-20

    Performance in H-mode DT plasmas in ITER with various choices of heating systems are predicted and compared. Combinations of external heating by Negative Ion Neutral Beam Injection (NNBI), Ion Cyclotron Range of Frequencies (ICRF), and Electron Cyclotron Heating (ECH) are assumed. Scans with a range of physics assumptions about boundary temperatures in the edge pedestal, alpha ash transport, and toroidal momentum transport are used to indicate effects of uncertainties. Time-dependent integrated modeling with the PTRANSP code is used to predict profiles of heating, beam torque, and plasma profiles. The GLF23 model is used to predict temperature profiles. Either GLF23 or the assumption of a constant ratio for χø/χi is used to predict toroidal rotation profiles driven by the beam torques. Large differences for the core temperatures are predicted with different mixes of the external heating during the density and current ramp-up phase, but the profiles are similar during the flattop phase. With χø/χi = 0.5, the predicted toroidal rotation is relatively slow and the flow shear implied by the pressure, toroidal rotation, and neoclassical poloidal rotation are not sufficient to cause significant changes in the energy transport or steady state temperature profiles. The GLF23-predicted toroidal rotation is faster by a factor of six, and significant flow shear effects are predicted.

  14. Determination of trace metal ions via on-line separation and preconcentration by means of chelating Sepharose beads in a sequential injection lab-on-valve (SI-LOV) system coupled to electrothermal atomic absorption spectrometric detection

    DEFF Research Database (Denmark)

    Long, Xiangbao; Hansen, Elo Harald; Miró, Manuel

    2005-01-01

    . The samples are adjusted to pH 5.0 on-line in the system for optimum operation. The target ions are adsorbed by chelation on the surface of the beads, contained in a 20 mul microcolumn within the LOV, and following elution by 50 mul 2M nitric acid, the eluate is, as sandwiched by air segments, introduced...

  15. Investigations on transport and storage of high ion beam intensities

    Energy Technology Data Exchange (ETDEWEB)

    Joshi, Ninad Shrikrishna

    2009-08-25

    In the framework of this thesis the intense low energy ion beam transport was investigated. Especially, the beam transport in toroidal magnetic field configurations was discussed, as it may allow the accumulation of high intensive beams in the future. One of the specific tasks is to design an injection system that can be used for the proposed low energy accumulator ring. A simulation code (TBT) was written to describe the particle motion in curved segments. Particle in Cell techniques were utilized to simulate a multi particle dynamics. A possibility of reading an external data file was made available so that a measured distribution can be used to compare simulation results with measured ones. A second order cloud in cell method was used to calculate charge density and in turn to solve Poisson's equation. Further simulations were performed to study the self field effects on beam transport. Experiments were performed to compare the simulation results and gain practical experience. The preparatory experiments consisted of building and characterization of the ion source in a first step. Along with the momentum spectrometer and emittance scanner the beam properties were studied. Low mass ion beams He{sup +} and mixed p, H{sup 2+}, H{sup 3+} beams were analyzed. In the second stage, beams were transported through a solenoid and the phase space distribution was measured as a function of the magnetic field for different beam energies. The phase-space as distributions measured in a first stage were simulated backward and then again forward transported through the solenoid. The simulated results were then compared with the measured distribution. The LINTRA transport program was used. The phase-space distribution was further simulated for transport experiments in a toroidal magnetic field. The transport program that was used to simulate the beam in the toroid was also used to design the injection system. The injection system with its special field configurations was

  16. Deceleration, precooling, and multi-pass stopping of highly charged ions in Be⁺ Coulomb crystals.

    Science.gov (United States)

    Schmöger, L; Schwarz, M; Baumann, T M; Versolato, O O; Piest, B; Pfeifer, T; Ullrich, J; Schmidt, P O; López-Urrutia, J R Crespo

    2015-10-01

    Preparing highly charged ions (HCIs) in a cold and strongly localized state is of particular interest for frequency metrology and tests of possible spatial and temporal variations of the fine structure constant. Our versatile preparation technique is based on the generic modular combination of a pulsed ion source with a cryogenic linear Paul trap. Both instruments are connected by a compact beamline with deceleration and precooling properties. We present its design and commissioning experiments regarding these two functionalities. A pulsed buncher tube allows for the deceleration and longitudinal phase-space compression of the ion pulses. External injection of slow HCIs, specifically Ar(13+), into the linear Paul trap and their subsequent retrapping in the absence of sympathetic cooling is demonstrated. The latter proved to be a necessary prerequisite for the multi-pass stopping of HCIs in continuously laser-cooled Be(+) Coulomb crystals.

  17. Deceleration, precooling, and multi-pass stopping of highly charged ions in Be{sup +} Coulomb crystals

    Energy Technology Data Exchange (ETDEWEB)

    Schmöger, L., E-mail: lisa.schmoeger@mpi-hd.mpg.de; Schwarz, M.; Versolato, O. O. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig (Germany); Baumann, T. M.; Piest, B.; Pfeifer, T.; Crespo López-Urrutia, J. R. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Ullrich, J. [Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig (Germany); Schmidt, P. O. [Physikalisch-Technische Bundesanstalt, Bundesallee 100, 38116 Braunschweig (Germany); Institut für Quantenoptik, Leibniz Universität Hannover, Welfengarten 1, 30167 Hannover (Germany)

    2015-10-15

    Preparing highly charged ions (HCIs) in a cold and strongly localized state is of particular interest for frequency metrology and tests of possible spatial and temporal variations of the fine structure constant. Our versatile preparation technique is based on the generic modular combination of a pulsed ion source with a cryogenic linear Paul trap. Both instruments are connected by a compact beamline with deceleration and precooling properties. We present its design and commissioning experiments regarding these two functionalities. A pulsed buncher tube allows for the deceleration and longitudinal phase-space compression of the ion pulses. External injection of slow HCIs, specifically Ar{sup 13+}, into the linear Paul trap and their subsequent retrapping in the absence of sympathetic cooling is demonstrated. The latter proved to be a necessary prerequisite for the multi-pass stopping of HCIs in continuously laser-cooled Be{sup +} Coulomb crystals.

  18. Effects of ion/ion proton transfer reactions on conformation of gas-phase cytochrome c ions.

    Science.gov (United States)

    Zhao, Qin; Schieffer, Gregg M; Soyk, Matthew W; Anderson, Timothy J; Houk, R S; Badman, Ethan R

    2010-07-01

    Positive ions from cytochrome c are studied in a 3-D ion trap/ion mobility (IM)/quadrupole-time-of-flight (TOF) instrument with three independent ion sources. The IM separation allows measurement of the cross section of the ions. Ion/ion reactions in the 3-D ion trap that remove protons cause the cytochrome c ions to refold gently without other degradation of protein structure, i.e., fragmentation or loss of heme group or metal ion. The conformation(s) of the product ions generated by ion/ion reactions in a given charge state are similar regardless of whether the cytochrome c ions are originally in +8 or +9 charge states. In the lower charge states (+1 to +5) cytochrome c ions made by the ion/ion reaction yield a single IM peak with cross section of approximately 1110 to 1180 A(2), even if the original +8 ion started with multiple conformations. The conformation expands slightly when the charge state is reduced from +5 to +1. For product ions in the +6 to +8 charge states, ions created from higher charge states (+9 to +16) by ion/ion reaction produce more compact conformation(s) in somewhat higher abundances compared with those produced directly by the electrospray ionization (ESI) source. For ions in intermediate charge states that have a variety of resolvable conformers, the voltage used to inject the ions into the drift tube, and the voltage and duration of the pulse that extracts ions from the ion trap, can affect the observed abundances of various conformers.

  19. Electron bunch injection at an angle into a laser wakefield

    CERN Document Server

    Luttikhof, M J H; Van Goor, F A; Boller, K -J

    2008-01-01

    External injection of electron bunches longer than the plasma wavelength in a laser wakefield accelerator can lead to the generation of femtosecond ultrarelativistic bunches with a couple of percent energy spread. Extensive study has been done on external electron bunch (e.g. one generated by a photo-cathode rf linac) injection in a laser wakefield for different configurations. In this paper we investigate a new way of external injection where the electron bunch is injected at a small angle into the wakefield. This way one can avoid the ponderomotive scattering as well as the vacuum-plasma transition region, which tend to destroy the injected bunch. In our simulations, the effect of the laser pulse dynamics is also taken into account. It is shown that injection at an angle can provide compressed and accelerated electron bunches with less than 2% energy spread. Another advantage of this scheme is that it has less stringent requirements in terms of the size of the injected bunch and there is the potential to tr...

  20. Neutral Beam Injection Experiments in the HL-1M Tokamak

    Institute of Scientific and Technical Information of China (English)

    严龙文; 雷光玖; 钟光武; 江涛; 周艳; 姜韶风; 丁玄同; 周才品; 刘永

    2003-01-01

    Neutral beam injection (NBI) experiments have been carried out with two operation modes of a bucket ion source in the HL-1M tokamak. During the first mode, more than 30% rise in ion temperature above the Ohmic level is routinely achieved after NBI power about 0. 5 MW is injected. Ion temperature only increases 20-30% for the second operation mode, which is often limited by current termination. The heating effects of the NBI have been analysed experimentally and theoretically. The performance of the NBI system is well described.

  1. Cosmic-ray electron injection from the ionization of nuclei

    CERN Document Server

    Morlino, G

    2009-01-01

    We show that the secondary electrons ejected from the ionization of heavy ions can be injected into the acceleration process that occurs at supernova remnant shocks. This electron injection mechanism works since ions are ionized during the acceleration when they move already with relativistic speed, just like ejected electrons do. Using the abundances of heavy nuclei measured in cosmic rays at Earth, we estimate the electron/proton ratio at the source to be ~10^-4, big enough to account for the nonthermal synchrotron emission observed in young SNRs. We also show that the ionization process can limit the maximum energy that heavy ions can reach.

  2. Cosmic-ray electron injection from the ionization of nuclei.

    Science.gov (United States)

    Morlino, Giovanni

    2009-09-18

    We show that the secondary electrons ejected from the ionization of heavy ions can be injected into the acceleration process that occurs at supernova remnant shocks. This electron injection mechanism works since ions are ionized during the acceleration when they move already with relativistic speed, just like ejected electrons do. Using the abundances of heavy nuclei measured in cosmic rays measured at the Earth, we estimate the electron/proton ratio at the source to be approximately 10;{-4}, big enough to account for the nonthermal synchrotron emission observed in young supernova remnants. We also show that the ionization process can limit the maximum energy that heavy ions can reach.

  3. Preparation of cold Mg{sup +}ion clouds for sympathetic cooling of highly charged ions at SPECTRAP

    Energy Technology Data Exchange (ETDEWEB)

    Cazan, Radu Mircea

    2012-02-15

    The bound electrons in hydrogen-like or lithium-like heavy ions experience extremely strong electric and magnetic fields in the surrounding of the nucleus. Laser spectroscopy of the ground-state hyperfine splitting in the lead region provides a sensitive tool to test strong-field quantum electro dynamics (QED), especially in the magnetic sector. Previous measurements on hydrogen-like systems performed in an electron-beam ion trap (EBIT) or at the experimental storage ring (ESR) were experimentally limited in accuracy due to statistics, the large Doppler broadening and the ion energy. The full potential of the QED test can only be exploited if measurements for hydrogen- and lithium-like ions are performed with accuracy improved by 2-3 orders of magnitude. Therefore, the new Penning trap setup SPECTRAP - dedicated for laser spectroscopy on trapped and cooled highly charged ions - is currently commissioned at GSI Darmstadt. Heavy highly charged ions will be delivered to this trap by the HITRAP facility in the future. SPECTRAP is a cylindrical Penning trap with axial access for external ion injection and radial optical access mounted inside a cold-bore superconducting Helmholtz-type split-coil magnet. To reach the targeted accuracy in laser spectroscopy, an efficient and fast cooling process for the highly charged ions must be employed. This can be realized by sympathetic cooling with a cloud of laser-cooled light ions. Within this thesis work, a laser system and an ion source for the production of such a {sup 24}Mg{sup +} ion cloud was developed and commissioned at SPECTRAP. An all-solid-state laser system for the generation of 279.6 nm light was designed and built. It consists of a fiber laser at 1118.5 nm followed by frequency quadrupling using two successive second-harmonic generation stages with actively stabilized ring resonators and nonlinear crystals. The laser system can deliver more than 15 mW of UV laser power under optimal conditions and requires little

  4. Epidural injections for back pain

    Science.gov (United States)

    ESI; Spinal injection for back pain; Back pain injection; Steroid injection - epidural; Steroid injection - back ... be pregnant What medicines you are taking, including herbs, supplements, and other drugs you bought without a ...

  5. External Measures of Cognition

    Directory of Open Access Journals (Sweden)

    Osvaldo eCairo

    2011-10-01

    Full Text Available The human brain is undoubtedly the most impressive, complex and intricate organ that has evolved over time. It is also probably the least understood, and for that reason, the one that is currently attracting the most attention. In fact, the number of comparative analyses that focus on the evolution of brain size in Homo sapiens and other species has increased dramatically in recent years. In neuroscience, no other issue has generated so much interest and been the topic of so many heated debates as the difference in brain size between socially defined population groups, both its connotations and implications. For over a century, external measures of cognition have been related to intelligence. However, it is still unclear whether these measures actually correspond to cognitive abilities. In summary, this paper must be reviewed with this premise in mind.

  6. Ion beam cooler-buncher at the IGISOL facility

    Energy Technology Data Exchange (ETDEWEB)

    Nieminen, A.; Hakala, J.; Huikari, J.; Kolhinen, V.S.; Rinta-Antila, S.; Szerypo, J. [Dept. of Physics, Univ. of Jyvaeskylae (Finland); Billowes, J.; Campbell, P.; Moore, I.D.; Moore, R. [Schuster Lab., Univ. of Manchester (United Kingdom); Forest, D.H.; Thayer, H.L.; Tungate, G. [School of Physics and Astronomy, Univ. of Birmingham, Edgbaston (United Kingdom); Jokinen, A.; Aeystoe, J. [Dept. of Physics, Univ. of Jyvaeskylae (Finland)]|[CERN, Geneva (Switzerland)

    2003-07-01

    An ion beam cooler-buncher for manipulating low-energy radioactive ion beams at the IGISOL facility is described. The cooler-buncher serves as a source of cooled ion bunches for collinear laser spectroscopy and it will be used for preparation of ion bunches for injection into a Penning trap system. (orig.)

  7. Interferometry with Strontium Ions

    Science.gov (United States)

    Jackson, Jarom; Lambert, Enoch; Otterstrom, Nils; Jones, Tyler; Durfee, Dallin

    2014-05-01

    We describe progress on a cold ion matter-wave interferometer. Cold Strontium atoms are extracted from an LVIS. The atoms will be photo-ionized with a two-photon transition to an auto-ionizing state in the continuum. The ions will be split and recombined using stimulated Raman transitions from a pair of diode lasers injection locked to two beams from a master laser which have been shifted up and down by half the hyperfine splitting. We are developing laser instrumentation for this project including a method to prevent mode-hopping by analyzing laser frequency noise, and an inexpensive, robust wavelength meter. Supported by NSF Award No. 1205736.

  8. A multiple sampling ionization chamber for the External Target Facility

    Science.gov (United States)

    Zhang, X. H.; Tang, S. W.; Ma, P.; Lu, C. G.; Yang, H. R.; Wang, S. T.; Yu, Y. H.; Yue, K.; Fang, F.; Yan, D.; Zhou, Y.; Wang, Z. M.; Sun, Y.; Sun, Z. Y.; Duan, L. M.; Sun, B. H.

    2015-09-01

    A multiple sampling ionization chamber used as a particle identification device for high energy heavy ions has been developed for the External Target Facility. The performance of this detector was tested with a 239Pu α source and RI beams. A Z resolution (FWHM) of 0.4-0.6 was achieved for nuclear fragments of 18O at 400 AMeV.

  9. Injection and acceleration of Au31+ in the BNL AGS.

    Energy Technology Data Exchange (ETDEWEB)

    Fischer,W.; Ahrens, L.; Brown, K.; Gardner, C.; Glenn, W.; Huang, H.; Mapes, M.; Smart, L.; Thieberger, P.; Tsoupas, N.; Zhang, S.Y.; Zeno, K.; Omet, C.; Spiller, P.

    2008-06-23

    Injection and acceleration of ions in a lower charge state reduces space charge effects, and, if further elcctron stripping is needed, may allow elimination of a stripping stage and the associated beam losses. The former is of interest to the accelerators in the GSI FAIR complex, the latter for BNL RHIC collider operation at energies lower than the current injection energy. Lower charge state ions, however, have a higher likelihood of electron stripping which can lead to dynamic pressures rises and subsequent beam losses. We report on experiments in the AGS where Au{sup 31+} ions were injected and accelerated instead of the normally used Au{sup 77+} ions. Beam intensities and the average pressure in the AGS ring are recorded, and compared with calculations for dynamic pressures and beam losses. The experimental results will be used to benchmark the StrahlSim dynamic vacuum code and will be incorporated in the GSI FAIR SIS100 design.

  10. Underground Injection Control (UIC)

    Science.gov (United States)

    Provide information on: individual injection well classes; regulations specific to each well class; technical guidance; compliance assistance; federal, state, and tribal/territory roles and responsibilities.

  11. Ferric Carboxymaltose Injection

    Science.gov (United States)

    ... pharmacist if you are allergic to ferric carboxymaltose injection, ferumoxytol (Feraheme), iron dextran (Dexferrum, Infed), iron sucrose (Venofer), or sodium ferric gluconate (Ferrlecit); any other ...

  12. Piezoelectric Injection Systems

    Science.gov (United States)

    Mock, R.; Lubitz, K.

    The origin of direct injection can be doubtlessly attributed to Rudolf Diesel who used air assisted injection for fuel atomisation in his first self-ignition engine. Although it became apparent already at that time that direct injection leads to reduced specific fuel consumption compared to other methods of fuel injection, it was not used in passenger cars for the moment because of its disadvantageous noise generation as the requirements with regard to comfort were seen as more important than a reduced specific consumption.

  13. Characterization of proanthocyanidins from Parkia biglobosa (Jacq.) G. Don. (Fabaceae) by Flow Injection Analysis-Electrospray Ionization Ion Trap Tandem Mass Spectrometry and Liquid Chromatography/Electrospray Ionization Mass Spectrometry.

    Science.gov (United States)

    Tala, Viviane Raïssa Sipowo; Candida da Silva, Viviane; Rodrigues, Clenilson Martins; Nkengfack, Augustin Ephrem; dos Santos, Lourdes Campaner; Vilegas, Wagner

    2013-03-01

    The present study investigates the chemical composition of the African plant Parkia biglobosa (Fabaceae) roots and barks by Liquid Chromatography-Electrospray Ionization and Direct Injection Tandem Mass Spectrometry analysis. Mass spectral data indicated that B-type oligomers are present, namely procyanidins and prodelphinidins, with their gallate and glucuronide derivatives, some of them in different isomeric forms. The analysis evidenced the presence of up to 40 proanthocyanidins, some of which are reported for the first time. In this study, the antiradical activity of extracts of roots and barks from Parkia biglobosa was evaluated using DPPH method and they showed satisfactory activities.

  14. Characterization of Proanthocyanidins from Parkia biglobosa (Jacq. G. Don. (Fabaceae by Flow Injection Analysis — Electrospray Ionization Ion Trap Tandem Mass Spectrometry and Liquid Chromatography/Electrospray Ionization Mass Spectrometry

    Directory of Open Access Journals (Sweden)

    Wagner Vilegas

    2013-03-01

    Full Text Available The present study investigates the chemical composition of the African plant Parkia biglobosa (Fabaceae roots and barks by Liquid Chromatography - Electrospray Ionization and Direct Injection Tandem Mass Spectrometry analysis. Mass spectral data indicated that B-type oligomers are present, namely procyanidins and prodelphinidins, with their gallate and glucuronide derivatives, some of them in different isomeric forms. The analysis evidenced the presence of up to 40 proanthocyanidins, some of which are reported for the first time. In this study, the antiradical activity of extracts of roots and barks from Parkia biglobosa was evaluated using DPPH method and they showed satisfactory activities.

  15. Polarized negative ions

    Energy Technology Data Exchange (ETDEWEB)

    Haeberli, W.

    1981-04-01

    This paper presents a survey of methods, commonly in use or under development, to produce beams of polarized negative ions for injection into accelerators. A short summary recalls how the hyperfine interaction is used to obtain nuclear polarization in beams of atoms. Atomic-beam sources for light ions are discussed. If the best presently known techniques are incorporated in all stages of the source, polarized H/sup -/ and D/sup -/ beams in excess of 10 ..mu..A can probably be achieved. Production of polarized ions from fast (keV) beams of polarized atoms is treated separately for atoms in the H(25) excited state (Lamb-Shift source) and atoms in the H(1S) ground state. The negative ion beam from Lamb-Shift sources has reached a plateau just above 1 ..mu..A, but this beam current is adequate for many applications and the somewhat lower beam current is compensated by other desirable characteristics. Sources using fast polarized ground state atoms are in a stage of intense development. The next sections summarize production of polarized heavy ions by the atomic beam method, which is well established, and by optical pumping, which has recently been demonstrated to yield very large nuclear polarization. A short discussion of proposed ion sources for polarized /sup 3/He/sup -/ ions is followed by some concluding remarks.

  16. Integrated semiconductor twin-microdisk laser under mutually optical injection

    Energy Technology Data Exchange (ETDEWEB)

    Zou, Ling-Xiu; Liu, Bo-Wen; Lv, Xiao-Meng; Yang, Yue-De; Xiao, Jin-Long; Huang, Yong-Zhen, E-mail: yzhuang@semi.ac.cn [State Key Laboratory on Integrated Optoelectronics, Institute of Semiconductors, Chinese Academy of Sciences, Beijing 100083 (China)

    2015-05-11

    We experimentally study the characteristics of an integrated semiconductor twin-microdisk laser under mutually optical injection through a connected optical waveguide. Based on the lasing spectra, four-wave mixing, injection locking, and period-two oscillation states are observed due to the mutually optical injection by adjusting the injected currents applied to the two microdisks. The enhanced 3 dB bandwidth is realized for the microdisk laser at the injection locking state, and photonic microwave is obtained from the electrode of the microdisk laser under the period-two oscillation state. The plentifully dynamical states similar as semiconductor lasers subject to external optical injection are realized due to strong optical interaction between the two microdisks.

  17. Electrolytic silver ion cell sterilizes water supply

    Science.gov (United States)

    Albright, C. F.; Gillerman, J. B.

    1968-01-01

    Electrolytic water sterilizer controls microbial contamination in manned spacecraft. Individual sterilizer cells are self-contained and require no external power or control. The sterilizer generates silver ions which do not impart an unpleasant taste to water.

  18. Ion-Ion Neutralization.

    Science.gov (United States)

    1980-12-31

    plasma were identified using a downstream quadrupole mass spectrometer. In these experimento it is a simple matter to establish H+(H 2 0):f as the...pressure as predicted by the Thomson t2rnary mechanism whicK hzr been suownr to be valid experimentally at hiTh rrsurs (,han and Peron, 1:EI4 hereafter t...of NO , NO2 ions in various gases and the ternary recombination coefficients of these ions in the higher pres:;ure ( Thomson ) re"ie. Equation (5) cr>n

  19. Measurement of negative ion density in a pulsed multicusp negative ion source

    Energy Technology Data Exchange (ETDEWEB)

    Coonan, B.; Mellon, K.N.; Hopkins, M.B. (Dublin City University, Dublin (Ireland))

    1992-10-05

    The production of negative ion beams for use in neutral beam injection heating has become an important area of research in recent years. This paper discusses the negative ion densities measured in a pulsed multicusp volume ion source using photodetachment diagnostic technique. A pulse modulated negative ion source is being used as an alternative to the tandem source and an increase in negative ion extracted current has previously been observed by Hopkins and Mellon. Work with photodetachment quoted in this paper shows an increase in negative ion density during the post discharge similar to previous results obtained using an accelerator to extract the negative ions.

  20. Influence of electron-ion collisions in plasma on the electron energy gain using the TE11 mode inside an elliptical waveguide

    Science.gov (United States)

    Abdoli-Arani, A.; Basiry, M. J.

    2016-09-01

    The influence of electron-ion collisions in plasma on the electron energy gain and total energy of an externally injected electron inside an elliptical waveguide, including collisional plasma using the transverse electric mode, is investigated. It is noted that microwave radiation is used for excitations of the TE11 even mode in the configuration. The electromagnetic field components of the TE11 mode in the considered waveguide are obtained and graphically presented. It is seen that the strength of the fields reduces in the collisional plasma. Furthermore, the deflection angle, energy gain of the electron and total energy of the electron due to the mode are obtained. It is illustrated that electron-ion collisions in plasma reduce the energy gain and total energy of electrons injected into the elliptical waveguide.

  1. Simultaneous determination of organic acids and inorganic anions in Danshen for injection (lyophilized powder) by ion chromatography%离子色谱法同时测定注射用丹参(冻干)中有机酸和无机阴离子

    Institute of Scientific and Technical Information of China (English)

    刘静; 李静; 聂黎行; 王钢力; 王英新; 林瑞超

    2012-01-01

    Objective: To establish an ion chromatography method for simultaneous determination of five organic acids (lactic acid, acetic acid, formic acid, succinic acid and oxalic acid) and two inorganic anions ( chloridion and nitrate) in Danshen for injection(lyophilized powder). Methods;Five organic acids and two inorganic anions were determined by anion exchange column Ion Pac ASH -HC,eluted by gradient hydroxide potassium(1 -50 mmol · L-1 ) and identified by suppressed conductivity detector ASRS 300 with self - circulation suppression mode. Results ; Good resolution can be achieved among the above mentioned five organic acids and two inorganic anions. Their linear correlations over the investigated concentration were in the range of 0. 9996 - 0. 9999 and 0. 9997 -0. 9999,while the average recoveries were 92. 4% - 105. 1% and 102. 0% - 103. 2% .respectively. Conclusion: The ion chromatography method is fast, accurate, simple, reliable and applicable for the assay and quality control of organic acids and inorganic anions in Danshen for injection(lyophilized powder).%目的:建立能够同时测定注射用丹参(冻干)中有机酸(乳酸、乙酸、甲酸、琥珀酸和草酸)和无机阴离子(氯离子和硝酸根离子)含量的离子色谱法.方法:以Ion Pac AS11-HC阴离子交换柱分离,1~50 mmol·L-1氢氧化钾溶液梯度淋洗,ASRS300型抑制器电导检测器检测,自循环抑制模式.结果:5个有机酸及2个无机阴离子基本达到分离,线性关系良好,相关系数分别在0.9996~0.9999和0.9997~0.9999,平均回收率分别在92.4%~105.1%和102.0% ~ 103.2%.结论:所建立的方法快速、准确、简便、实用,可用于注射用丹参(冻干)中有机酸和无机阴离子的含量测定和质量控制.

  2. Lithium pellet injection experiments on the Alcator C-Mod tokamak

    Energy Technology Data Exchange (ETDEWEB)

    Garnier, D.T.

    1996-06-01

    A pellet enhanced performance mode, showing significantly reduced core transport, is regularly obtained after the injection of deeply penetrating lithium pellets into Alcator C-Mod discharges. These transient modes, which typically persist about two energy confinement times, are characterized by a steep pressure gradient ({ell}{sub p} {le} a/5) in the inner third of the plasma, indicating the presence of an internal transport barrier. Inside this barrier, particle and energy diffusivities are greatly reduced, with ion thermal diffusivity dropping to near neoclassical values. Meanwhile, the global energy confinement time shows a 30% improvement over ITER89-P L-mode scaling. The addition of ICRF auxiliary heating shortly after the pellet injection leads to high fusion reactivity with neutron rates enhanced by an order of magnitude over L-mode discharges with similar input powers. A diagnostic system for measuring equilibrium current density profiles of tokamak plasmas, employing high speed lithium pellets, is also presented. Because ions are confined to move along field lines, imaging the Li{sup +} emission from the toroidally extended pellet ablation cloud gives the direction of the magnetic field. To convert from temporal to radial measurements, the 3-D trajectory of the pellet is determined using a stereoscopic tracking system. These measurements, along with external magnetic measurements, are used to solve the Grad-Shafranov equation for the magnetic equilibrium of the plasma. This diagnostic is used to determine the current density profile of PEP modes by injection of a second pellet during the period of good confinement. This measurement indicates that a region of reversed magnetic shear exists at the plasma core. This current density profile is consistent with TRANSP calculations for the bootstrap current created by the pressure gradient. MHD stability analysis indicates that these plasmas are near the n = {infinity} and the n = 1 marginal stability limits.

  3. A compact chaotic laser device with a two-dimensional external cavity structure

    Energy Technology Data Exchange (ETDEWEB)

    Sunada, Satoshi, E-mail: sunada@se.kanazawa-u.ac.jp; Adachi, Masaaki [Faculty of Mechanical Engineering, Institute of Science and Engineering, Kanazawa University, Kakuma-machi, Kanazawa, Ishikawa 920-1192 (Japan); Fukushima, Takehiro [Department of Information and Communication Engineering, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197 (Japan); Shinohara, Susumu; Arai, Kenichi [NTT Communication Science Laboratories, NTT Corporation, 2-4 Hikaridai, Seika-cho, Soraku-gun, Kyoto 619-0237 (Japan); Harayama, Takahisa [NTT Communication Science Laboratories, NTT Corporation, 2-4 Hikaridai, Seika-cho, Soraku-gun, Kyoto 619-0237 (Japan); Department of Mechanical Engineering, Toyo University, 2100 Kujirai, Kawagoe, Saitama 350-8585 (Japan)

    2014-06-16

    We propose a compact chaotic laser device, which consists of a semiconductor laser and a two-dimensional (2D) external cavity for delayed optical feedback. The overall size of the device is within 230 μm × 1 mm. A long time delay sufficient for chaos generation can be achieved with the small area by the multiple reflections at the 2D cavity boundary, and the feedback strength is controlled by the injection current to the external cavity. We experimentally demonstrate that a variety of output properties, including chaotic output, can be selectively generated by controlling the injection current to the external cavity.

  4. Procedural and Physical Interventions for Vaccine Injections

    Science.gov (United States)

    Shah, Vibhuti; McMurtry, C. Meghan; MacDonald, Noni E.; Ipp, Moshe; Riddell, Rebecca Pillai; Noel, Melanie; Chambers, Christine T.

    2015-01-01

    Background: This systematic review evaluated the effectiveness of physical and procedural interventions for reducing pain and related outcomes during vaccination. Design/Methods: Databases were searched using a broad search strategy to identify relevant randomized and quasi-randomized controlled trials. Data were extracted according to procedure phase (preprocedure, acute, recovery, and combinations of these) and pooled using established methods. Results: A total of 31 studies were included. Acute infant distress was diminished during intramuscular injection without aspiration (n=313): standardized mean difference (SMD) −0.82 (95% confidence interval [CI]: −1.18, −0.46). Injecting the most painful vaccine last during vaccinations reduced acute infant distress (n=196): SMD −0.69 (95% CI: −0.98, −0.4). Simultaneous injections reduced acute infant distress compared with sequential injections (n=172): SMD −0.56 (95% CI: −0.87, −0.25). There was no benefit of simultaneous injections in children. Less infant distress during the acute and recovery phases combined occurred with vastus lateralis (vs. deltoid) injections (n=185): SMD −0.70 (95% CI: −1.00, −0.41). Skin-to-skin contact in neonates (n=736) reduced acute distress: SMD −0.65 (95% CI: −1.05, −0.25). Holding infants reduced acute distress after removal of the data from 1 methodologically diverse study (n=107): SMD −1.25 (95% CI: −2.05, −0.46). Holding after vaccination (n=417) reduced infant distress during the acute and recovery phases combined: SMD −0.65 (95% CI: −1.08, −0.22). Self-reported fear was reduced for children positioned upright (n=107): SMD −0.39 (95% CI: −0.77, −0.01). Non-nutritive sucking (n=186) reduced acute distress in infants: SMD −1.88 (95% CI: −2.57, −1.18). Manual tactile stimulation did not reduce pain across the lifespan. An external vibrating device and cold reduced pain in children (n=145): SMD −1.23 (95% CI: −1.58, −0

  5. External fixators in haemophilia.

    Science.gov (United States)

    Lee, V; Srivastava, A; PalaniKumar, C; Daniel, A J; Mathews, V; Babu, N; Chandy, M; Sundararaj, G D

    2004-01-01

    External fixators (EF) are not commonly used for patients with haemophilia. We describe the use of EF (Ilizarov, AO- uni- and bi-planar fixators and Charnley clamp) in nine patients (mean age: 19.2 years; range: 9-37) with haemophilia for the following indications - arthrodesis of infected joints, treatment of open fractures and osteoclasis. EF required an average of nine skin punctures [range: 4-17 were maintained for a period of 15 weeks (range: 8-29.5), without regular factor replacement, till bone healing was adequate and were removed with a single dose of factor infusion]. The mean preoperative factor level achieved was 85% (range: 64-102%). Much lower levels were subsequently maintained till wound healing. The average total factor consumption was 430 IU kg(-1) (range: 240-870), administered over a period of 17 days (range: 9-44). There were no major complications related to EF except in a patient who developed inhibitors. In conclusion, EF can be used safely in haemophilic patients who do not have inhibitors and does not require prolonged factor replacement.

  6. [Intra-articular injections].

    Science.gov (United States)

    Chapelle, Ch

    2015-09-01

    It is not unusual for a specialist or general practitioner to be presented with a pathology which necessitates the use of an intra-articular injection of corticosteroids, hyaluronic acid or a local anaesthetic. It would seem to be interesting to update and to precise the techniques and methods of intraarticular injections which have appeared in recent international publications, when we know that 30 % of the injections given into the knee and so called "dry" are incorrect and, therefore, inefficient. The indication of an articular injection depends, firstly, on the diagnosis which should be done with great care; after which should be an objective analysis complete with secondary effects linked to both the injection and the product used. The conditions of asepsis, the choice of needles and quantities of the injection and even the ways of the injections should be reviewed in detail. The last studies clearly question the secondary effects of the cartilage degradations of the cortisone given as an intra-articular injection and shows its efficiency on the pain and inflammatory phenomonen in osteoarthritis. Studies on hyaluronic acid are often contradictory going from a modest result to an important pain relief but it is necessary to be aware that the objective criteria are difficult to interpret. The use of local anaesthetics in intra-articular is limited by the few indications in view of the major risk of aggravating the pre-existing lesions by the disappearing signs of pain.

  7. Injection of Deuterium Pellets

    DEFF Research Database (Denmark)

    Sørensen, H.; Andersen, P.; Andersen, S. A.

    1984-01-01

    A pellet injection system made for the TFR tokamak at Fontenay-aux-Roses, Paris is described. 0.12-mg pellets are injected with velocities of around 600-700 m/s through a 5-m long guide tube. Some details of a new light gas gun are given; with this gun, hydrogen pellets are accelerated...

  8. Corticotropin, Repository Injection

    Science.gov (United States)

    H.P. Acthar Gel® ... Corticotropin repository injection comes as a long acting gel to inject under the skin or into a ... prescription and nonprescription medications, vitamins, nutritional supplements, or herbal products you are taking or plan to take. ...

  9. Separably injective Banach spaces

    CERN Document Server

    Avilés, Antonio; Castillo, Jesús M F; González, Manuel; Moreno, Yolanda

    2016-01-01

    This monograph contains a detailed exposition of the up-to-date theory of separably injective spaces: new and old results are put into perspective with concrete examples (such as l∞/c0 and C(K) spaces, where K is a finite height compact space or an F-space, ultrapowers of L∞ spaces and spaces of universal disposition). It is no exaggeration to say that the theory of separably injective Banach spaces is strikingly different from that of injective spaces. For instance, separably injective Banach spaces are not necessarily isometric to, or complemented subspaces of, spaces of continuous functions on a compact space. Moreover, in contrast to the scarcity of examples and general results concerning injective spaces, we know of many different types of separably injective spaces and there is a rich theory around them. The monograph is completed with a preparatory chapter on injective spaces, a chapter on higher cardinal versions of separable injectivity and a lively discussion of open problems and further lines o...

  10. Dimethyl Ether Injection Studies

    DEFF Research Database (Denmark)

    Sorenson, Spencer C.; Glensvig, Michael; Abata, Duane L.

    1998-01-01

    effects of DME in high pressure injection have also been observed. DME has a higher compressibility than diesel fuel, resulting in larger pressure oscillations in the injection system during the injection process. The oscillations with DME also have a slower delay rate than those of diesel fuel......A series of preliminary investigations has been performed in order to investigate the behavior of DME in a diesel injection environment. These studies have in-cluded visual observations of the spray penetration and angles for high pressure injection into Nitrogen using conventional jerk pump...... in the same system. As a first attempt to simulate combustion of DME in Diesel engines, the results of the spray studies have been incorporated into a simplified spray combustion model. A turbulent jet structure was adjusted to fit the penetration rates of the observed sprays. The observed spray widths agreed...

  11. Skepticism, contextualism, externalism and modality

    National Research Council Canada - National Science Library

    Ron Wilburn

    2006-01-01

    .... However, because efforts to contextualize externalism via subjunctive conditional analysis court circularity, it is only on an internalistic interpretation that contextualist strategies can even be motivated...

  12. A large-area RF source for negative hydrogen ions

    Science.gov (United States)

    Frank, P.; Feist, J. H.; Kraus, W.; Speth, E.; Heinemann, B.; Probst, F.; Trainham, R.; Jacquot, C.

    1998-08-01

    In a collaboration with CEA Cadarache, IPP is presently developing an rf source, in which the production of negative ions (H-/D-) is being investigated. It utilizes PINI-size rf sources with an external antenna and for the first step a small size extraction system with 48 cm2 net extraction area. First results from BATMAN (Ba¯varian T_est Ma¯chine for N_egative Ions) show (without Cs) a linear dependence of the negative ion yield with rf power, without any sign of saturation. At elevated pressure (1.6 Pa) a current density of 4.5 mA/cm2 H- (without Cs) has been found so far. At medium pressure (0.6 Pa) the current density is lower by approx. a factor of 5, but preliminary results with Cesium injection show a relative increase by almost the same factor in this pressure range. Langmuir probe measurements indicate an electron temperature Te>2 eV close to the plasma grid with a moderate magnetic filter (700 Gcm). Attempts to improve the performance by using different magnetic configurations and different wall materials are under way.

  13. Resonance methods in quadrupole ion traps

    Science.gov (United States)

    Snyder, Dalton T.; Peng, Wen-Ping; Cooks, R. Graham

    2017-01-01

    The quadrupole ion trap is widely used in the chemical physics community for making measurements on dynamical systems, both intramolecular (e.g. ion fragmentation reactions) and intermolecular (e.g. ion/molecule reactions). In this review, we discuss linear and nonlinear resonances in quadrupole ion traps, an understanding of which is critical for operation of these devices and interpretation of the data which they provide. The effect of quadrupole field nonlinearity is addressed, with important implications for promoting fragmentation and achieving unique methods of mass scanning. Methods that depend on ion resonances (i.e. matching an external perturbation with an ion's induced frequency of motion) are discussed, including ion isolation, ion activation, and ion ejection.

  14. ExternE transport methodology for external cost evaluation of air pollution

    DEFF Research Database (Denmark)

    Jensen, S. S.; Berkowicz, R.; Brandt, J.

    The report describes how the human exposure estimates based on NERI's human exposure modelling system (AirGIS) can improve the Danish data used for exposure factors in the ExternE Transport methodology. Initially, a brief description of the ExternE Tranport methodology is given and it is summaris...... how the methodology has been applied so far in a previous Danish study. Finally, results of a case study are reported. Exposure factors have been calculated for various urban categories in the Greater Copenhagen Area...

  15. ExternE transport methodology for external cost evaluation of air pollution (DK)

    Energy Technology Data Exchange (ETDEWEB)

    Solvang Jensen, S.; Berkowicz, R.; Brandt, J. [National Environmental Research Inst., Dept. of Atmospheric Environment (Denmark); Willumsen, E.; Kristensen, N.B. [COWI (Denmark)

    2004-07-01

    The report describes how the human exposure estimates based on NERI's human exposure modelling system (AiGIS) can improve the Danish data used for exposure factors in the ExternE Transport methodology. Inititally, a brief description of the ExternE Transport methodology is given and it is summarised how the methodology has been applied so far in a previous Danish study. Finally, results of a case study are reported. Exposure factors have been calculated for various urban categories in the Greater Copenhagen Area. (au)

  16. Injection moulding antireflective nanostructures

    DEFF Research Database (Denmark)

    Christiansen, Alexander Bruun; Clausen, Jeppe Sandvik; Mortensen, N. Asger

    in an injection moulding process, to fabricate the antireflective surfaces. The cycle-time was 35 s. The injection moulded structures had a height of 125 nm, and the visible spectrum reflectance of injection moulded black polypropylene surfaces was reduced from 4.5±0.5% to 2.5±0.5%. The gradient of the refractive...... index of the nanostructured surfaces was estimated from atomic force micrographs and the theoretical reflectance was calculated using the transfer matrix method and effective medium theory. The measured reflectance shows good agreement with the theory of graded index antireflective nanostructures...

  17. ALICE Injected Beam Accidents

    CERN Document Server

    Appleby, R B

    2009-01-01

    The ALICE (point 2) interaction region is sensitive to beam orbit errors arising from magnet setting errors on injection. In this report, beam accident scenarios under injection for ALICE are described, focusing on ultra- fast error injection scenarios for the interaction straight correctors and dipoles. Beam 1 and beam 2 accident scenarios are considered, where the errors can lead to beam orbits striking the ALICE vacuum chamber or elements of the machine. The required thresholds for magnet current interlocks are calculated to avoid machine and detector risk.

  18. LHCb Injected Beam Accidents

    CERN Document Server

    Appleby, R B

    2009-01-01

    The LHCb (point 8) interaction region is sensitive to beam orbit errors arising from magnet setting errors on injection. In this report, beam accident scenarios under injection for LHCb are described, focusing on ultra- fast error injection scenarios for the interaction straight correctors and dipoles. Beam 1 and beam 2 accident scenarios are considered, where the errors can lead to beam orbits striking the LHCb vacuum chamber or elements of the machine. The required thresholds for magnet current interlocks are calculated to avoid machine and detector risk.

  19. External coating of colonic anastomoses

    DEFF Research Database (Denmark)

    Pommergaard, Hans-Christian; Achiam, Michael Patrick; Rosenberg, Jacob

    2012-01-01

    Colon anastomotic leakage remains both a frequent and serious complication in gastrointestinal surgery. External coating of colonic anastomoses has been proposed as a means to lower the rate of this complication. The aim of this review was to evaluate existing studies on external coating of colonic...

  20. Retrofitting Systems for External Walls

    DEFF Research Database (Denmark)

    Rose, Jørgen

    1997-01-01

    In this report, 9 different external and internal retrofitting systems are analyzed using numerical calculations. The analysis focuses on the thermal bridge effects in the different systems, and on this basis it is discussed whether internal or external retrofitting has the most advantages...

  1. Common injections in musculoskeletal medicine.

    Science.gov (United States)

    Monseau, Aaron J; Nizran, Parminder Singh

    2013-12-01

    Musculoskeletal injections are a common procedure in primary care and sports medicine but can be intimidating for some clinicians. This article addresses current evidence for corticosteroid injections, and common injection indications and techniques, namely knee, subacromial bursa, glenohumeral joint, lateral epicondyle, de Quervain tenosynovitis, and greater trochanteric bursa injections. Preparation for injections and some evidence for ultrasound guidance are also reviewed.

  2. Development of devices for self-injection: using tribological analysis to optimize injection force

    Directory of Open Access Journals (Sweden)

    Lange J

    2016-05-01

    Full Text Available Jakob Lange, Leos Urbanek, Stefan BurrenYpsomed Delivery Systems, Ypsomed AG, Burgdorf, Switzerland Abstract: This article describes the use of analytical models and physical measurements to characterize and optimize the tribological behavior of pen injectors for self-administration of biopharmaceuticals. One of the main performance attributes of this kind of device is its efficiency in transmitting the external force applied by the user on to the cartridge inside the pen in order to effectuate an injection. This injection force characteristic is heavily influenced by the frictional properties of the polymeric materials employed in the mechanism. Standard friction tests are available for characterizing candidate materials, but they use geometries and conditions far removed from the actual situation inside a pen injector and thus do not always generate relevant data. A new test procedure, allowing the direct measurement of the coefficient of friction between two key parts of a pen injector mechanism using real parts under simulated use conditions, is presented. In addition to the absolute level of friction, the test method provides information on expected evolution of friction over lifetime as well as on expected consistency between individual devices. Paired with an analytical model of the pen mechanism, the frictional data allow the expected overall injection system force efficiency to be estimated. The test method and analytical model are applied to a range of polymer combinations with different kinds of lubrication. It is found that material combinations used without lubrication generally have unsatisfactory performance, that the use of silicone-based internal lubricating additives improves performance, and that the best results can be achieved with external silicone-based lubricants. Polytetrafluoroethylene-based internal lubrication and external lubrication are also evaluated but found to provide only limited benefits unless used in

  3. Electron string ion sources for carbon ion cancer therapy accelerators

    CERN Document Server

    Boytsov, A Yu; Donets, E D; Donets, E E; Katagiri, K; Noda, K; Ponkin, D O; Ramzdorf, A Yu; Salnikov, V V; Shutov, V B

    2015-01-01

    The Electron String type of Ion Sources (ESIS) was developed, constructed and tested first in the Joint Institute for Nuclear Research. These ion sources can be the appropriate sources for production of pulsed C4+ and C6+ ion beams which can be used for cancer therapy accelerators. In fact the test ESIS Krion-6T already now at the solenoid magnetic field only 4.6 T provides more than 10^10 C4+ ions per pulse and about 5*10^9 C6+ ions per pulse. Such ion sources could be suitable for application at synchrotrons. It was also found, that Krion-6T can provide more than 10^11 C6+ ions per second at 100 Hz repetition rate, and the repetition rate can be increased at the same or larger ion output per second. This makes ESIS applicable at cyclotrons as well. As for production of 11C radioactive ion beams ESIS can be the most economic kind of ion source. To proof that the special cryogenic cell for pulse injection of gaseous species into electron string was successfully tested using the ESIS Krion-2M.

  4. Rapid determination of nicotine in urine by direct thermal desorption ion trap mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Wise, M.B.; Ilgner, R.H.; Guerin, M.R.

    1990-01-01

    The measurement of nicotine and cotinine in physiological fluids (urine, blood serum, and saliva) is widely used as a means of assessing human exposure to environmental tobacco smoke (ETS). Although numerous analytical methods exist for these measurements, they generally involve extensive sample preparation which increases cost and decreases sample throughput. We report the use of thermal desorption directly into an ion trap mass spectrometer (ITMS) for the rapid determination of nicotine and cotinine in urine. A 1{mu}L aliquot of urine is injected into a specially designed inlet and flash vaporized directly into an ITMS through an open-split capillary restrictor interface. Isobutane chemical ionization is used to generate (M+H){sup +} ions of the analytes and collision induced dissociation is used to generate characteristic fragment ions which are used to confirm their identity. Quantification is achieved by integrating the ion current for the characteristic ions and comparing with an external working curve. Detection limits are approximately 50 pg per analyte and the sample turnaround time is approximately 3 minutes without the need for extensive sample preparation. 12 refs., 5 figs.

  5. Performance Targets and External Benchmarking

    DEFF Research Database (Denmark)

    Friis, Ivar; Hansen, Allan; Vámosi, Tamás S.

    Research on relative performance measures, transfer pricing, beyond budgeting initiatives, target costing, piece rates systems and value based management has for decades underlined the importance of external benchmarking in performance management. Research conceptualises external benchmarking...... the conditions upon which the market mechanism is performing within organizations. This paper aims to contribute to research by providing more insight to the conditions for the use of external benchmarking as an element in performance management in organizations. Our study explores a particular type of external...... towards the conditions for the use of the external benchmarks we provide more insights to some of the issues and challenges that are related to using this mechanism for performance management and advance competitiveness in organizations....

  6. Mouse bladder wall injection.

    Science.gov (United States)

    Fu, Chi-Ling; Apelo, Charity A; Torres, Baldemar; Thai, Kim H; Hsieh, Michael H

    2011-07-12

    Mouse bladder wall injection is a useful technique to orthotopically study bladder phenomena, including stem cell, smooth muscle, and cancer biology. Before starting injections, the surgical area must be cleaned with soap and water and antiseptic solution. Surgical equipment must be sterilized before use and between each animal. Each mouse is placed under inhaled isoflurane anesthesia (2-5% for induction, 1-3% for maintenance) and its bladder exposed by making a midline abdominal incision with scissors. If the bladder is full, it is partially decompressed by gentle squeezing between two fingers. The cell suspension of interest is intramurally injected into the wall of the bladder dome using a 29 or 30 gauge needle and 1 cc or smaller syringe. The wound is then closed using wound clips and the mouse allowed to recover on a warming pad. Bladder wall injection is a delicate microsurgical technique that can be mastered with practice.

  7. IncobotulinumtoxinA Injection

    Science.gov (United States)

    ... injected into a muscle, it blocks the nerve signals that cause uncontrollable tightening and movements of the ... any of these symptoms, do not drive a car, operate machinery, or do other dangerous activities.if ...

  8. Amphotericin B Liposomal Injection

    Science.gov (United States)

    ... lining of the spinal cord and brain) and visceral leishmaniasis (a parasitic disease that usually affects spleen, ... complex injection: fever, chills, nausea, vomiting, flushing, back pain with or without chest tightness, chest pain, shortness ...

  9. PS injection area

    CERN Multimedia

    1974-01-01

    To the right is the PS ring viewed along the direction of the protons. At the left the injection line coming from the 50 MeV Linac 1 (bottom) and going towards the 800 MeV booster, or deflected to the right to be injected directly into straight section 16. The drumlike element behind the (blue) dipole magnet is a 'debuncher' (a 200 MHz cavity). See photos 7409014X and 7409009.

  10. Injection and Dump Systems

    CERN Document Server

    Bracco, C; Barnes, M J; Carlier, E; Drosdal, L N; Goddard, B; Kain, V; Meddahi, M; Mertens, V; Uythoven, J

    2012-01-01

    Performance and failures of the LHC injection and ex- traction systems are presented. In particular, a comparison with the 2010 run, lessons learnt during operation with high intensity beams and foreseen upgrades are described. UFOs, vacuum and impedance problems related to the injection and extraction equipment are analysed together with possible improvements and solutions. New implemented features, diagnostics, critical issues of XPOC and IQC applications are addressed.

  11. High-frequency signal generation using 1550 nm VCSEL subject to two-frequency optical injection

    Science.gov (United States)

    Consoli, Antonio; Quirce, Ana; Valle, Angel; Esquivias, Ignacio; Pesquera, Luis; García Tijero, Jose Manuel

    2013-03-01

    We experimentally investigate high-frequency microwave signal generation using a 1550 nm single-mode VCSEL subject to two-frequency optical injection. We first consider a situation in which the injected signals come from two similar VCSELs. The polarization of the injected light is parallel to that of the injected VCSEL. We obtain that the VCSEL can be locked to one of the injected signals, but the observed microwave signal is originated by beating at the photodetector. In a second situation we consider injected signals that come from two external cavity tunable lasers with a significant increase of the injected power with respect to the VCSEL-by-VCSEL injection case. The polarization of the injected light is orthogonal to that of the free-running slave VCSEL. We show that in this case it is possible to generate a microwave signal inside the VCSEL cavity.

  12. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev, S.; Dickerson, C.; Levand, A.; Ostroumov, P. N.; Pardo, R. C.; Savard, G.; Vondrasek, R. [Physics Division, Argonne National Laboratory, Argonne, Illinois 60439 (United States); Alessi, J.; Beebe, E.; Pikin, A. [Collider-Accelerator Department, Brookhaven National Laboratory, Upton, New York 11973 (United States); Kuznetsov, G. I.; Batazova, M. A. [Budker Institute of Nuclear Physics, Novosibirsk 630090 (Russian Federation)

    2012-02-15

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  13. Development of electron beam ion source charge breeder for rare isotopes at Californium Rare Isotope Breeder Upgrade

    Energy Technology Data Exchange (ETDEWEB)

    Kondrashev S.; Alessi J.; Dickerson, C.; Levand, A.; Ostroumov, P.N.; Pardo, R.C.; Savard, G.; Vondrasek, R.; Beebe, E.; Pikin, A.; Kuznetsov, G.I.; Batazova, M.A.

    2012-02-03

    Recently, the Californium Rare Isotope Breeder Upgrade (CARIBU) to the Argonne Tandem Linac Accelerator System (ATLAS) was commissioned and became available for production of rare isotopes. Currently, an electron cyclotron resonance ion source is used as a charge breeder for CARIBU beams. To further increase the intensity and improve the purity of neutron-rich ion beams accelerated by ATLAS, we are developing a high-efficiency charge breeder for CARIBU based on an electron beam ion source (EBIS). The CARIBU EBIS charge breeder will utilize the state-of-the-art EBIS technology recently developed at Brookhaven National Laboratory (BNL). The electron beam current density in the CARIBU EBIS trap will be significantly higher than that in existing operational charge-state breeders based on the EBIS concept. The design of the CARIBU EBIS charge breeder is nearly complete. Long-lead components of the EBIS such as a 6-T superconducting solenoid and an electron gun have been ordered with the delivery schedule in the fall of 2011. Measurements of expected breeding efficiency using the BNL Test EBIS have been performed using a Cs{sup +} surface ionization ion source for external injection in pulsed mode. In these experiments we have achieved {approx}70% injection/extraction efficiency and breeding efficiency into the most abundant charge state of {approx}17%.

  14. New Developments of a Laser Ion Source for Ion Synchrotrons

    CERN Document Server

    Kondrashev, S; Konukov, K; Sharkov, B Yu; Shumshurov, A V; Camut, O; Chamings, J A; Kugler, H; Scrivens, R; Charushin, A; Makarov, K; Satov, Yu; Smakovskii, Yu

    2004-01-01

    Laser Ion Sources (LIS) are well suited to filling synchrotron rings with highly charged ions of almost any element in a single turn injection mode. We report the first measurements of the LIS output parameters for Pb27+ ions generated by the new 100 J/1 Hz Master Oscillator - Power Amplifier CO2-laser system. A new LIS has been designed, built and tested at CERN, as an ion source for ITEP-TWAC accelerator/accumulator facility, and as a possible future source for an upgrade of the Large Hadron Collider (LHC) injector chain. The use of the LIS based on 100 J/1 Hz CO2-laser together with the new ion LINAC, as injector for ITEP-TWAC project, is discussed..

  15. Charge breeding investigation in EBIS/T and collision study of ions with cold atoms for HITRAP

    Energy Technology Data Exchange (ETDEWEB)

    Sokolov, Alexey

    2010-01-29

    Highly charged ions (HCI) at low velocities or at rest are interesting systems for various atomic physics experiments. For investigations on HCI of heavy stable or radioactive nuclides the HITRAP (Highly charged Ion TRAP) decelerator facility has been set up at GSI to deliver cooled beams of HCI at an energy of 5 keV/q. The HCI are produced in a stripper foil at relativistic energies and are decelerated in several steps at ESR storage ring and HITRAP before they are delivered to experimental setups. One of the experiments is the investigation of multi-electron charge exchange in collisions of heavy HCI with cold atoms using novel MOTRIMS technique. Collision experiments on light ions from an ECR ion source colliding with cold atoms in a MOT have been performed and the results are described. An electron beam ion trap (EBIT) has been tested and optimized for commissioning of the HITRAP physics experiments. The process of charge breeding in the EBIT has been successfully studied with gaseous elements and with an alkaline element injected from an external ion source. (orig.)

  16. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L.; Sieverts Nielsen, P.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results; to aggregate these site- and technology-specific results to more general figures. The current report covers the results of the national implementation for Denmark. Three different fuel cycles have been chosen as case studies. These are fuel cycles for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant based on biogas. The report covers all the details of the application of the methodology to these fuel cycles aggregation to a national level. (au) EU-JOULE 3. 59 tabs., 25 ills., 61 refs.

  17. Properties of autonomous and injection locked flux flow oscillators

    DEFF Research Database (Denmark)

    Mygind, Jesper; Koshelets, V. P.; Shchukin, A. V.;

    1995-01-01

    performed both for two autonomous FFOs and with one of the FFOs injection-locked to a narrow-band external microwave source. By beating the two autonomous FFOs an integral spectral linewidth as low as 750 kHz is measured at 280 GHz. Mechanisms leading to a broadening of the FFO linewidth are discussed...

  18. Greatly Increasing Trapped Ion Populations for Mobility Separations Using Traveling Waves in Structures for Lossless Ion Manipulations

    Energy Technology Data Exchange (ETDEWEB)

    Deng, Liulin; Ibrahim, Yehia M.; Garimella, Sandilya V. B.; Webb, Ian K.; Hamid, Ahmed M.; Norheim, Randolph V.; Prost, Spencer A.; Sandoval, Jeremy A.; Baker, Erin S.; Smith, Richard D.

    2016-10-18

    The initial use of traveling waves (TW) for ion mobility (IM) separations using a structures for lossless ion manipulations (SLIM) employed an ion funnel trap (IFT) to accumulate ions from a continuous electrospray ionization source, and limited to injected ion populations of ~106 charges due to the onset of space charge effects in the trapping region. Additional limitations arise due to the loss of resolution for the injection of ions over longer periods (e.g. in extended pulses). In this work a new SLIM ‘flat funnel’ (FF) module has been developed and demonstrated to enable the accumulation of much larger ion populations and their injection for IM separations. Ion current measurements indicate a capacity of ~3.2×108 charges for the extended trapping volume, over an order of magnitude greater than the IFT. The orthogonal ion injection into a funnel shaped separation region can greatly reduce space charge effects during the initial IM separation stage, and the gradually reduced width of the path allows the ion packet to be increasingly compressed in the lateral dimension as the separation progresses, allowing e.g. efficient transmission through conductance limits or compatibility with subsequent ion manipulations. This work examined the TW, RF, and DC confining field SLIM parameters involved in ion accumulation, injection, transmission and separation in the FF IM module using both direct ion current and MS measurements. Wide m/z range ion transmission is demonstrated, along with significant increases in signal to noise (S/N) ratios due to the larger ion populations injected. Additionally, we observed a reduction in the chemical background, which was attributed to more efficient desolvation of solvent related clusters over the extended ion accumulation periods. The TW SLIM FF IM module is anticipated to be especially effective as a front end for long path SLIM IM separation modules.

  19. Greatly Increasing Trapped Ion Populations for Mobility Separations Using Traveling Waves in Structures for Lossless Ion Manipulations.

    Science.gov (United States)

    Deng, Liulin; Ibrahim, Yehia M; Garimella, Sandilya V B; Webb, Ian K; Hamid, Ahmed M; Norheim, Randolph V; Prost, Spencer A; Sandoval, Jeremy A; Baker, Erin S; Smith, Richard D

    2016-10-07

    The initial use of traveling waves (TW) for ion mobility (IM) separations using structures for lossless ion manipulations (SLIM) employed an ion funnel trap (IFT) to accumulate ions from a continuous electrospray ionization source and was limited to injected ion populations of ∼10(6) charges due to the onset of space charge effects in the trapping region. Additional limitations arise due to the loss of resolution for the injection of ions over longer periods, such as in extended pulses. In this work a new SLIM "flat funnel" (FF) module has been developed and demonstrated to enable the accumulation of much larger ion populations and their injection for IM separations. Ion current measurements indicate a capacity of ∼3.2 × 10(8) charges for the extended trapping volume, over an order of magnitude greater than that of the IFT. The orthogonal ion injection into a funnel shaped separation region can greatly reduce space charge effects during the initial IM separation stage, and the gradually reduced width of the path allows the ion packet to be increasingly compressed in the lateral dimension as the separation progresses, allowing efficient transmission through conductance limits or compatibility with subsequent ion manipulations. This work examined the TW, rf, and dc confining field SLIM parameters involved in ion accumulation, injection, transmission, and IM separation in the FF module using both direct ion current and MS measurements. Wide m/z range ion transmission is demonstrated, along with significant increases in the signal-to-noise ratios (S/N) due to the larger ion populations injected. Additionally, we observed a reduction in the chemical background, which was attributed to more efficient desolvation of solvent related clusters over the extended ion accumulation periods. The TW SLIM FF IM module is anticipated to be especially effective as a front end for long path SLIM IM separation modules.

  20. Effects of Potassium Currents upon Action Potential of Cardiac Cells Exposed to External Electric fields

    Institute of Scientific and Technical Information of China (English)

    An-Ying Zhang; Xiao-Feng Pang

    2008-01-01

    Previous studies show that exposure to high-voltage electric fields would influence the electro cardiogram both in experimental animate and human beings. The effects of the external electric fields upon action potential of cardiac cells are studied in this paper based on the dynamical model, LR91. Fourth order Runger-Kuta is used to analyze the change of potassium ion channels exposed to external electric fields in detail. Results indicate that external electric fields could influence the current of potassium ion by adding an induced component voltage on membrane. This phenomenon might be one of the reasons of heart rate anomaly under the high-voltage electric fields.

  1. Internal standard versus external standard calibration: an uncertainty case study of a liquid chromatography analysis

    Directory of Open Access Journals (Sweden)

    Elcio Cruz de Oliveira

    2010-01-01

    Full Text Available Traditionally, in the cigarettes industry, the determination of ammonium ion in the mainstream smoke is performed by ion chromatography. This work studies this determination and compares the results of this technique with the use of external and internal standard calibration. A reference cigarette sample presented measurement uncertainty of 2.0 μg/cigarette and 1.5 μg/cigarette, with external and internal standard, respectively. It is observed that the greatest source of uncertainty is the bias correction factor and that it is even more significant when using external standard, confirming thus the importance of internal standardization for this correction.

  2. External fuel thermionic reactor system.

    Science.gov (United States)

    Mondt, J. F.; Peelgren, M. L.

    1971-01-01

    Thermionic reactors are prime candidates for nuclear electric propulsion. The national thermionic reactor effort is concentrated on the flashlight concept with the external-fuel concept as the backup. The external-fuel concept is very adaptable to a completely modular power subsystem which is attractive for highly reliable long-life applications. The 20- to 25-cm long, externally-fueled converters have been designed, fabricated, and successfully tested with many thermal cycles by electrical heating. However, difficulties have been encountered during encapsulation for nuclear heated tests and none have been started to date. These nuclear tests are required to demonstrate the concept feasibility.

  3. Combination of external loads

    Energy Technology Data Exchange (ETDEWEB)

    Frandsen, S.; Tarp Johansen, N.J.; Joergensen, H. [Forskningscenter Risoe, Roskilde (Denmark); Gravesen, H.; Soerensen, S.L. [Carl Bro, Glostrup (Denmark); Pedersen, J. [Elsam Engineering, Fredericia (Denmark); Zorn, R.; Hvidberg Knudsen, M. [DHI Water and Environment, Hoersholm (Denmark); Voelund, P. [Energi E2, Koebenhavn (Denmark)

    2003-09-01

    The project onbectives have been: To improve and consequently opimise the basis for design of offshore wind turbines. This is done through 1) mapping the wind, wave ice and current as well as correlations of these, and 2) by clarifyring how these external conditions transform into loads. A comprehensive effort has been made to get a thorough understanding of the uncertainties that govern the reliability of wind turbines with respect to wind and wave loading. One of the conclusions is that the reliability of wind turbines is generally lower, than the average reliability of building structures that are subject not only to environmental loads, which are very uncertain, but also imposed loads and self weight, which are less uncertain than the environmental loads. The implication is that, at the moment lower load partial safety factors for onshore wind turbines cannot be recommended. For the combination of wind and wave design loads the problem is twofold: 1). A very conservative design will be generated by simply adding the individual wind and wave design loads disregarding the independence of the short-term fluctuations of wind and wave loads. 2). Characteristic values and partial safety factors for wind and wave loads are not defined similarly. This implies that the reliability levels of turbine support structures subject to purely aerodynamic loads and subject to purely hydrodynamic loads are not identical. For the problem of combining aerodynamic design loads and hydrodynamic design loads two results have been obtained in the project: 1). By simple means a site specific wave load safety factor rendering the same safety level for hydrodynamic loads as for aerodynamic loads is derived, and next, by direct square summation of extreme fluctuations, the wind and wave load safety factors are weighted. 2). Under the assumptions that a deep water site is considered and that the wave loading is a fifty-fifty mix of drag and inertia the same wind and wave load safety factor

  4. Preliminary optimal ion-exchange technology of saccharification liquid made from broken rice for preparing glucose injection by response surface methodology%效应面法优选碎米制备注射用葡萄糖中糖化液离子交换工艺的初步研究

    Institute of Scientific and Technical Information of China (English)

    石继连; 杨岩涛; 刘文龙; 邓凯文; 戴儒文; 唐昱; 贺福元

    2013-01-01

    采用星点设计-效应面法优化碎米糖化液离子交换的工艺条件.以树脂装量、pH和洗脱流速为考察因素,以洗脱指数为效应值,分别采用多元线性回归和二项式方程拟合,用效应面法优化工艺,并进行预测分析.碎米糖化液离子交换的优化工艺为:在两支10mm×20cm的层析柱中分别加入阳、阴离子交换树脂10g,分别调pH为4.0、10.0后,在常温下以10d/min的速度洗脱.本文所建立的离子交换工艺简单可行,可为进一步制备注射用葡萄糖的离子交换工艺研究提供实验依据.%To optimize the ion-exchange technology conditions of saccharification liquid from broken rice by central composite design and response surface methodology.Taking resin loading quantity, pH and elution speed as investigation factors,and the elution efficiency as effect size.The multiple linear regression and binomial equation were fitted respectively,and response surface methodology was adopted to optimize the technology,predict and analyze the possible result.The optimum technology for ion-exchange conditions of saccharification liquid from broken rice was like this:10g cation exchange resin(pH4.0)and 10g anion exchange resin(pH 10.0)were added into two chromatographic columns ( 10mm ×20cm) severally, eluted at the speed of 10d/min under room temperature.The above-mentioned experiment proved the ion-exchange technology was simple,and practicable, and it could provide experimental basis for ion - exchange technology research on further preparation of the glucose injection.

  5. Injection of photoelectrons into dense argon gas

    CERN Document Server

    Borghesani, A F

    2010-01-01

    The injection of photoelectrons in a gaseous or liquid sample is a widespread technique to produce a cold plasma in a weakly--ionized system in order to study the transport properties of electrons in a dense gas or liquid. We report here the experimental results of photoelectron injection into dense argon gas at the temperatureT=142.6 K as a function of the externally applied electric field and gas density. We show that the experimental data can be interpreted in terms of the so called Young-Bradbury model only if multiple scattering effects due to the dense environment are taken into account when computing the scattering properties and the energetics of the electrons.

  6. External costs related to power production technologies. ExternE national implementation for Denmark

    Energy Technology Data Exchange (ETDEWEB)

    Schleisner, L.; Sieverts Nielsen, P. [eds.

    1997-12-01

    The objective of the ExternE National Implementation project has been to establish a comprehensive and comparable set of data on externalities of power generation for all EU member states and Norway. The tasks include the application of the ExternE methodology to the most important fuel cycles for each country as well as to update the already existing results, to aggregate these site- and technology-specific results to more general figures. The current report covers the detailed information concerning the ExternE methodology. Importance is attached to the computer system used in the project and the assessment of air pollution effects on health, materials and ecological effects. Also the assessment of global warming damages are described. Finally the report covers the detailed information concerning the national implementation for Denmark for an offshore wind farm and a wind farm on land, a decentralised CHP plant based on natural gas and a decentralised CHP plant base on biogas. (au) EU-JOULE 3. 79 tabs., 11 ills., 201 refs.

  7. Syringe-injectable electronics.

    Science.gov (United States)

    Liu, Jia; Fu, Tian-Ming; Cheng, Zengguang; Hong, Guosong; Zhou, Tao; Jin, Lihua; Duvvuri, Madhavi; Jiang, Zhe; Kruskal, Peter; Xie, Chong; Suo, Zhigang; Fang, Ying; Lieber, Charles M

    2015-07-01

    Seamless and minimally invasive three-dimensional interpenetration of electronics within artificial or natural structures could allow for continuous monitoring and manipulation of their properties. Flexible electronics provide a means for conforming electronics to non-planar surfaces, yet targeted delivery of flexible electronics to internal regions remains difficult. Here, we overcome this challenge by demonstrating the syringe injection (and subsequent unfolding) of sub-micrometre-thick, centimetre-scale macroporous mesh electronics through needles with a diameter as small as 100 μm. Our results show that electronic components can be injected into man-made and biological cavities, as well as dense gels and tissue, with >90% device yield. We demonstrate several applications of syringe-injectable electronics as a general approach for interpenetrating flexible electronics with three-dimensional structures, including (1) monitoring internal mechanical strains in polymer cavities, (2) tight integration and low chronic immunoreactivity with several distinct regions of the brain, and (3) in vivo multiplexed neural recording. Moreover, syringe injection enables the delivery of flexible electronics through a rigid shell, the delivery of large-volume flexible electronics that can fill internal cavities, and co-injection of electronics with other materials into host structures, opening up unique applications for flexible electronics.

  8. Syringe injectable electronics

    Science.gov (United States)

    Hong, Guosong; Zhou, Tao; Jin, Lihua; Duvvuri, Madhavi; Jiang, Zhe; Kruskal, Peter; Xie, Chong; Suo, Zhigang; Fang, Ying; Lieber, Charles M.

    2015-01-01

    Seamless and minimally-invasive three-dimensional (3D) interpenetration of electronics within artificial or natural structures could allow for continuous monitoring and manipulation of their properties. Flexible electronics provide a means for conforming electronics to non-planar surfaces, yet targeted delivery of flexible electronics to internal regions remains difficult. Here, we overcome this challenge by demonstrating syringe injection and subsequent unfolding of submicrometer-thick, centimeter-scale macroporous mesh electronics through needles with a diameter as small as 100 micrometers. Our results show that electronic components can be injected into man-made and biological cavities, as well as dense gels and tissue, with > 90% device yield. We demonstrate several applications of syringe injectable electronics as a general approach for interpenetrating flexible electronics with 3D structures, including (i) monitoring of internal mechanical strains in polymer cavities, (ii) tight integration and low chronic immunoreactivity with several distinct regions of the brain, and (iii) in vivo multiplexed neural recording. Moreover, syringe injection enables delivery of flexible electronics through a rigid shell, delivery of large volume flexible electronics that can fill internal cavities and co-injection of electronics with other materials into host structures, opening up unique applications for flexible electronics. PMID:26053995

  9. Externality and burnout among dentists.

    Science.gov (United States)

    St-Yves, A; Freeston, M H; Godbout, F; Poulin, L; St-Amand, C; Verret, M

    1989-12-01

    This study investigates the relationship between burnout as measured by the Maslach Burnout Inventory and locus of control as measured by the Adult Nowicki-Strickland Internal-External Locus of Control (ANS-IE) for 82 dentists. Significant Pearson correlations between two Maslach subscales and locus of control show Personal Accomplishment to be negatively associated -.31 and Emotional Exhaustion to be positively correlated .21 to externality.

  10. Relatie interne en externe audit

    OpenAIRE

    Ghys, Emelie

    2011-01-01

    In het eerste hoofdstuk wordt de probleemstelling van deze eindverhandeling besproken. Interne en externe audit worden de laatste jaren internationaal en nationaal meer en meer erkend in het bedrijfsleven. Aanleiding voor de toenemende belangstelling van de interne en externe auditfunctie zijn de verschillende boekhoudschandalen rond corporate governance of deugdelijk bestuur. Deze financiële mislukkingen leidden wereldwijd tot diverse wetten, nieuwe regels en verbeterde standaarden om zo een...

  11. Performance Targets and External Benchmarking

    DEFF Research Database (Denmark)

    Friis, Ivar; Hansen, Allan; Vámosi, Tamás S.

    as a market mechanism that can be brought inside the firm to provide incentives for continuous improvement and the development of competitive advances. However, whereas extant research primarily has focused on the importance and effects of using external benchmarks, less attention has been directed towards...... towards the conditions for the use of the external benchmarks we provide more insights to some of the issues and challenges that are related to using this mechanism for performance management and advance competitiveness in organizations....

  12. Parallel External Memory Graph Algorithms

    DEFF Research Database (Denmark)

    Arge, Lars Allan; Goodrich, Michael T.; Sitchinava, Nodari

    2010-01-01

    In this paper, we study parallel I/O efficient graph algorithms in the Parallel External Memory (PEM) model, one o f the private-cache chip multiprocessor (CMP) models. We study the fundamental problem of list ranking which leads to efficient solutions to problems on trees, such as computing lowest...... an optimal speedup of ¿(P) in parallel I/O complexity and parallel computation time, compared to the single-processor external memory counterparts....

  13. A solid state paramagnetic maser device driven by electron spin injection

    NARCIS (Netherlands)

    Watts, S. M.; van Wees, B. J.

    2006-01-01

    In response to an external, microwave-frequency magnetic field, a paramagnetic medium will absorb energy from the field that drives the magnetization dynamics. Here we describe a new process by which an external spin-injection source, when combined with the microwave field spin pumping, can drive

  14. A solid state paramagnetic maser device driven by electron spin injection

    NARCIS (Netherlands)

    Watts, S. M.; van Wees, B. J.

    2006-01-01

    In response to an external, microwave-frequency magnetic field, a paramagnetic medium will absorb energy from the field that drives the magnetization dynamics. Here we describe a new process by which an external spin-injection source, when combined with the microwave field spin pumping, can drive th

  15. Process in high energy heavy ion acceleration

    Science.gov (United States)

    Dinev, D.

    2009-03-01

    A review of processes that occur in high energy heavy ion acceleration by synchrotrons and colliders and that are essential for the accelerator performance is presented. Interactions of ions with the residual gas molecules/atoms and with stripping foils that deliberately intercept the ion trajectories are described in details. These interactions limit both the beam intensity and the beam quality. The processes of electron loss and capture lie at the root of heavy ion charge exchange injection. The review pays special attention to the ion induced vacuum pressure instability which is one of the main factors limiting the beam intensity. The intrabeam scattering phenomena which restricts the average luminosity of ion colliders is discussed. Some processes in nuclear interactions of ultra-relativistic heavy ions that could be dangerous for the performance of ion colliders are represented in the last chapter.

  16. 大体积直接进样离子色谱法测定饮用水中痕量溴酸盐的方法研究%Determination of trace bromate in drinking water by Large volume direct injection ion chromatography method

    Institute of Scientific and Technical Information of China (English)

    杨国栋

    2012-01-01

    Objective:To establish a large volume direct injection ion chromatography method for conductivity detection of bro-mate in drinking water. Methods; Dionex ICS -20Q0 ion chromatography, EGC II KOH eluent generator, Dionex Ionpac AS19 analytical column, DS6 thermal conductivity detector and ASRS300 anion suppressor were involved in this method. The 10 mmol/L~35 mmol/L KOH was used for gradient elution at the flow rate of 1. 00 ml/min, and the injection volume was 500 ul. Results:It was obtained from the experiment that the correlation coefficient was 0.9999, precision was RSD < 2% , average recoveries were between 95.0% ~ 107% and the minimum detection limit was 5 ug/L. Conclusion; The method has the advantages of simple operation, rapidness, high sensitivity, good reproducibility, which can be used for the analysis of trace bro-roate in drinking water.%目的:建立一种大体积直接进样,电导检测饮用水中痕量溴酸盐的离子色谱分析法.方法:采用Dionex ICS -2000型离子色谱仪,EGCⅡKOH淋洗液自动发生器,10 mmol/L~ 35 mmol/L KOH梯度淋洗,流速1.00 ml/min,Dionex Ionpac AS19型分析柱,DS6型热电导检测器,ASRS300阴离子抑制器,进样体积500μl等分析条件.结果:经实验得到相关系数r =0.9999,精密度RSD <2%,平均加标回收率在95.0%~107%之间,方法的最低检出限为5μg/L.结论:该方法具有操作简单、快速、灵敏度高、重现性好等优点,可应用于饮用水中痕量溴酸盐的分析测定.

  17. External Costs Related to Power Production Technologies

    DEFF Research Database (Denmark)

    Ibsen, Liselotte Schleisner; Nielsen, Per Sieverts

    1997-01-01

    The European Commission has launched a major study project, ExternE, to develop a methodology to quantify externalities. A “National Implementation Phase”, was started under the Joule II programme with the purpose of implementing the ExternE methodology in all member states. The main objective...

  18. External Costs Related to Power Production Technologies

    DEFF Research Database (Denmark)

    Ibsen, Liselotte Schleisner; Nielsen, Per Sieverts

    1997-01-01

    The European Commission has launched a major study project, ExternE, to develop a methodology to quantify externalities. A “National Implementation Phase”, was started under the Joule II programme with the purpose of implementing the ExternE methodology in all member states. The main objective of...

  19. Ion Colliders

    CERN Document Server

    Fischer, W

    2014-01-01

    High-energy ion colliders are large research tools in nuclear physics to study the Quark-Gluon-Plasma (QGP). The range of collision energy and high luminosity are important design and operational considerations. The experiments also expect flexibility with frequent changes in the collision energy, detector fields, and ion species. Ion species range from protons, including polarized protons in RHIC, to heavy nuclei like gold, lead and uranium. Asymmetric collision combinations (e.g. protons against heavy ions) are also essential. For the creation, acceleration, and storage of bright intense ion beams, limits are set by space charge, charge change, and intrabeam scattering effects, as well as beam losses due to a variety of other phenomena. Currently, there are two operating ion colliders, the Relativistic Heavy Ion Collider (RHIC) at BNL, and the Large Hadron Collider (LHC) at CERN.

  20. High-resolution field desorption/ionization fourier transform ion cyclotron resonance mass analysis of nonpolar molecules.

    Science.gov (United States)

    Schaub, Tanner M; Hendrickson, Christopher L; Qian, Kuangnan; Quinn, John P; Marshall, Alan G

    2003-05-01

    We report the first field desorption ionization broadband high-resolution (m/Deltam(50%) approximately 65 000) mass spectra. We have interfaced a field ionization/field desorption source to a home-built 9.4-T FT-ICR mass spectrometer. The instrumental configuration employs convenient sample introduction (in-source liquid injection) and external ion accumulation. We demonstrate the utility of this configuration by generating high-resolution positive-ion mass spectra of C(60) and a midboiling crude oil distillate. The latter contains species not accessible by common soft-ionization methods, for example, low-voltage electron ionization, electrospray ionization, and matrix-assisted laser desorption/ionization. The present work demonstrates significant advantages of FI/FD FT-ICR MS for analysis of nonpolar molecules in complex mixtures.

  1. A multiple sampling ionization chamber for the External Target Facility

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, X.H., E-mail: zhxh@impcas.ac.cn [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Tang, S.W.; Ma, P.; Lu, C.G.; Yang, H.R.; Wang, S.T.; Yu, Y.H.; Yue, K.; Fang, F. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Yan, D.; Zhou, Y.; Wang, Z.M.; Sun, Y. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Sun, Z.Y.; Duan, L.M. [Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou 730000 (China); Sun, B.H. [School of Physics and Nuclear Energy Engineering, Beihang University, Beijing 100191 (China)

    2015-09-21

    A multiple sampling ionization chamber used as a particle identification device for high energy heavy ions has been developed for the External Target Facility. The performance of this detector was tested with a {sup 239}Pu α source and RI beams. A Z resolution (FWHM) of 0.4–0.6 was achieved for nuclear fragments of {sup 18}O at 400 AMeV.

  2. Influence of the external component on the damage of the bipolar transistor induced by the electromagnetic pulse

    Science.gov (United States)

    Xiaowen, Xi; Changchun, Chai; Xingrong, Ren; Yintang, Yang; Zhenyang, Ma; Jing, Wang

    2010-07-01

    A study on the influence of the external resistor and the external voltage source during the injection of the electromagnetic pulse (EMP) into the bipolar transistor (BJT) is carried out. Research shows that the increase of the external resistor Rb at base makes the burnout time of the device decrease slightly, the increase of the external voltage source Vbe at base can aid the damage of the device when the magnitude of the injecting voltage is relatively low and has little influence when the magnitude is sufficiently high causing the device appearing the PIN structure damage, and the increase of the external resistor Re can remarkably reduce the voltage drops added to the device and improve the durability of the device. In the final analysis, the effect of the external circuit component on the BJT damage is the influence on the condition which makes the device appear current-mode second breakdown.

  3. Influence of the external component on the damage of the bipolar transistor induced by the electromagnetic pulse

    Energy Technology Data Exchange (ETDEWEB)

    Xi Xiaowen; Chai Changchun; Ren Xingrong; Yang Yintang; Ma Zhenyang; Wang Jing, E-mail: xixiaowen523103@163.co [Key Laboratory of Ministry of Education for Wide Band-Gap Semiconductor Materials and Devices, School of Microelectronics, Xidian University, Xi' an 710071 (China)

    2010-07-15

    A study on the influence of the external resistor and the external voltage source during the injection of the electromagnetic pulse (EMP) into the bipolar transistor (BJT) is carried out. Research shows that the increase of the external resistor R{sub b} at base makes the burnout time of the device decrease slightly, the increase of the external voltage source V{sub be} at base can aid the damage of the device when the magnitude of the injecting voltage is relatively low and has little influence when the magnitude is sufficiently high causing the device appearing the PIN structure damage, and the increase of the external resistor R{sub e} can remarkably reduce the voltage drops added to the device and improve the durability of the device. In the final analysis, the effect of the external circuit component on the BJT damage is the influence on the condition which makes the device appear current-mode second breakdown.

  4. Particle retention in porous media: Applications to water injectivity decline

    Energy Technology Data Exchange (ETDEWEB)

    Wennberg, Kjell Erik

    1998-12-31

    This thesis studies the problem of migration and deposition of colloidal particles within porous media, theoretically and by computerized simulation. Special emphasis is put on the prediction of injectivity decline in water injection wells due to inherent particles in the injection water. The study of particle deposition within porous media requires a correct prediction of the deposition rate or filtration coefficient. A thorough review of the modeling approaches used in the past are combined with new ideas in order to arrive at an improved model for the prediction of the filtration coefficient. A new way of determining the transition time for the dominant deposition mechanism to change from internal deposition to external cake formation is proposed. From this fundamental theory, equations are given for water injectivity decline predictions. A computer program called WID for water injectivity decline predictions was developed. Using water quality, formation properties, injection rate/pressure and completion information as input, WID predicts decline in vertical and horizontal injection wells with openhole, perforated and fractured completions. The calculations agree fairly well with field data; in some cases the agreement is excellent. A poor match in a few cases indicates that more mechanisms may be responsible for injectivity decline than those presently accounted for by the simulator. The second part of the study deals with a theoretical investigation of the multi-dimensional nature of particle deposition in porous media. 112 refs., 100 figs., 9 tabs.

  5. Intracytoplasmic Sperm Injection (ICSI)

    Science.gov (United States)

    ... sperm must attach to the outside of the egg. Once attached, the sperm pushes through the outer layer to the inside ... in vitro fertilization (IVF) to help fertilize the egg. During ICSI, a single sperm is injected directly into the cytoplasm the egg. ...

  6. Water injection dredging

    NARCIS (Netherlands)

    Verhagen, H.J.

    2000-01-01

    Some twenty years ago WIS-dredging has been developed in the Netherlands. By injecting water into the mud layer, the water content of the mud becomes higher, it becomes fluid mud and will start to flow. The advantages of this system are that there is no need of transporting the mud in a hopper, and

  7. Giving an insulin injection

    Science.gov (United States)

    ... an alcohol wipe on your injection site. The insulin needs to go into the fat layer under the skin. Pinch the skin and put the needle in at a 45º angle. If your tissues are thick enough, you may be able to ...

  8. Molecular ion sources for low energy semiconductor ion implantation (invited)

    Energy Technology Data Exchange (ETDEWEB)

    Hershcovitch, A., E-mail: hershcovitch@bnl.gov [Brookhaven National Laboratory, Upton, New York 11973 (United States); Gushenets, V. I.; Bugaev, A. S.; Oks, E. M.; Vizir, A.; Yushkov, G. Yu. [High Current Electronics Institute, Siberian Branch of Russian Academy of Sciences, Tomsk 634055 (Russian Federation); Seleznev, D. N.; Kulevoy, T. V.; Kozlov, A.; Kropachev, G. N.; Kuibeda, R. P.; Minaev, S. [Institute for Theoretical and Experimental Physics, Moscow 117218 (Russian Federation); Dugin, S.; Alexeyenko, O. [State Scientific Center of the Russian Federation State Research Institute for Chemistry and Technology of Organoelement Compounds, Moscow (Russian Federation)

    2016-02-15

    Smaller semiconductors require shallow, low energy ion implantation, resulting space charge effects, which reduced beam currents and production rates. To increase production rates, molecular ions are used. Boron and phosphorous (or arsenic) implantation is needed for P-type and N-type semiconductors, respectively. Carborane, which is the most stable molecular boron ion leaves unacceptable carbon residue on extraction grids. A self-cleaning carborane acid compound (C{sub 4}H{sub 12}B{sub 10}O{sub 4}) was synthesized and utilized in the ITEP Bernas ion source resulting in large carborane ion output, without carbon residue. Pure gaseous processes are desired to enable rapid switch among ion species. Molecular phosphorous was generated by introducing phosphine in dissociators via 4PH{sub 3} = P{sub 4} + 6H{sub 2}; generated molecular phosphorous in a pure gaseous process was then injected into the HCEI Calutron-Bernas ion source, from which P{sub 4}{sup +} ion beams were extracted. Results from devices and some additional concepts are described.

  9. A new method for rapid screening of low energy ion injected recombinant strain by PCR technology%一种基于 PCR 技术快速筛选低能离子注入重组菌株的方法

    Institute of Scientific and Technical Information of China (English)

    钱卫东; 周颖欣; 吴启航; 蔡长龙

    2016-01-01

    To expand application widely based on low energy ion beam mediating medicinal plants transformed yeast genomic DNA and constructing capable of producing natural prod-ucts in recombinant yeast strains .In this paper ,gentiopicroside biosynthetic pathway of key enzyme genes (GGPPS ,MECPS and MECT ) act as molecular screening marker .Recombi-nant strains DNA was amplificated for PCR ,which transformed to obtain as a template based on inject ation low energy ions to achieve high throughput screening for recombinant yeast strains .And the fermentation products abtained by screening strain were analyzed in HPLC . 12 candidate recombinant yeast strains were screened from 1 072 transformed yeast by HPLC repeat screening ,and 5 strains of fermentation product was detected gentiopicroside .The re-sult showed the PCR screening method was efficient ,simple ,short cycle ,the advantages of low-cost ,easy operation ,which was suitable for low energy ion beam mediated genomic DNA molecules randomly transformed yeast ,and applied in biosynthesis of natural products for yeast recombinant strains .%为拓展基于低能离子注入介导药用植物基因组DNA转化酵母、构建能生产天然产物的酵母重组菌的广泛应用,以目标产物龙胆苦苷生物合成途径中的关键酶基因(GGPPS , MECPS和MECT)为分子筛选标记,以基于低能离子注入随机转化重组菌DNA为模板进行PCR扩增,实现对其高通量初筛,利用HPLC方法对初筛所得菌株发酵产物进行分析检测。结果,从1072株转化酵母菌中初筛出12株候选酵母重组菌,经HPLC复筛后,其中5株重组酵母菌的发酵产物中检测出龙胆苦苷。研究表明,此PCR筛选方法,具有高效、简单、周期短、廉价、易于操作等优点,适用于低能离子注入介导基因组DNA大分子随机转化酵母,构建能生物合成天然产物的酵母重组菌的研究中。

  10. ALL-FERRITE RHIC INJECTION KICKER

    Energy Technology Data Exchange (ETDEWEB)

    HAHN,H.; FISCHER,W.; PTITSYN,V.I.; TUOZZOLO,J.E.

    2001-06-18

    Ion beams are transferred from the AGS into RHIC in boxcar fashion as single bunches. The nominal design assumes 60 bunches per ring but increasing the number of bunches to gain luminosity is possible, thereby requiring injection kickers with a shorter rise time. The original injection system consists of traveling-wave dielectric loaded kicker magnets and a Blumlein pulser with a rise time adequate for the present operation. Voltage breakdown in the dielectric kickers suggested the use of all-ferrite magnets. In order to minimize the conversion cost, the design of the all-ferrite kicker uses the same components as the dielectric loaded units. The all-ferrite kickers showed in bench measured good breakdown properties and a current rise time of < 50 ns. A prototype kicker has been installed in the blue ring and was tested with beam. Beam measurements indicate suitability of all-ferrite kicker magnets for upgraded operation.

  11. Initial measurements of O-ion and He-ion decay rates observed from the Van Allen probes RBSPICE instrument

    OpenAIRE

    Gerrard, Andrew; Lanzerotti, Louis; Gkioulidou, Matina; Mitchell, Donald; Manweiler, Jerry; Bortnik, Jacob; Keika, Kunihiro

    2014-01-01

    H-ion (∼45 keV to ∼600 keV), He-ion (∼65 keV to ∼520 keV), and O-ion (∼140 keV to ∼1130 keV) integral flux measurements, from the Radiation Belt Storm Probe Ion Composition Experiment (RBSPICE) instrument aboard the Van Allan Probes spacecraft B, are reported. These abundance data form a cohesive picture of ring current ions during the first 9 months of measurements. Furthermore, the data presented herein are used to show injection characteristics via the He-ion/H-ion abundance ratio and the ...

  12. Numerical Simulation and Interpretation of the Results of Lead Ion Production in the ECR Ion Source at CERN

    CERN Document Server

    Haseroth, H; Langbein, K; Shirkov, G D

    1995-01-01

    A new library of the computer codes for the mathematical simulation of heavy ion production in the ECR ion source is presented. These codes are based on the equations of model of ion confinement and losses in ECR ion sources. The ECR4 developed at GANIL is now used for lead ion production for the accelerator complex at CERN. An ion pulse with a current of up to 100 emA of Pb27+ has been regularly injected into the linac since May 1994. The results of numerical simulation with these computer codes and interpretation of experimental data of lead ion production in the ECR source at CERN are presented.

  13. Thermodynamic cost of external control

    Science.gov (United States)

    Barato, Andre C.; Seifert, Udo

    2017-07-01

    Artificial molecular machines are often driven by the periodic variation of an external parameter. This external control exerts work on the system of which a part can be extracted as output if the system runs against an applied load. Usually, the thermodynamic cost of the process that generates the external control is ignored. Here, we derive a refined second law for such small machines that include this cost, which is, for example, generated by free energy consumption of a chemical reaction that modifies the energy landscape for such a machine. In the limit of irreversible control, this refined second law becomes the standard one. Beyond this ideal limiting case, our analysis shows that due to a new entropic term unexpected regimes can occur: the control work can be smaller than the extracted work and the work required to generate the control can be smaller than this control work. Our general inequalities are illustrated by a paradigmatic three-state system.

  14. Leveraging External Sources of Innovation

    DEFF Research Database (Denmark)

    West, Joel; Bogers, Marcel

    2014-01-01

    This paper reviews research on open innovation that considers how and why firms commercialize external sources of innovations. It examines both the “outside-in” and “coupled” modes of open innovation. From an analysis of prior research on how firms leverage external sources of innovation...... cited work beyond those journals. A review of 291 open innovation-related publications from these sources shows that the majority of these articles indeed address elements of this inbound open innovation process model. Specifically, it finds that researchers have front-loaded their examination...... external innovations create value rather than how firms capture value from those innovations. Finally, the interaction phase considers both feedback for the linear process and reciprocal innovation processes such as cocreation, network collaboration, and community innovation. This review and synthesis...

  15. Injectivity decline prediction for Campos Basin reservoirs; Previsao da perda de injetividade para reservatorios da Bacia de Campos

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Adriano dos [Universidade Federal do Rio Grande do Norte (UFRN), Natal, RN (Brazil); Bedrikovetsky, Pavel [Universidade Estadual do Norte Fluminense (UENF), Campos dos Goytacazes, RJ (Brazil); Furtado, Claudio J.A. [PETROBRAS S.A., Rio de Janeiro, RJ (Brazil). Centro de Pesquisas (CENPES)

    2008-07-01

    A simulator for prediction of injectivity decline in perforated water injection wells is presented. The model parameters (filtration and formation damage coefficients) were determined from history data fitting, allowing injectivity decline prediction for various perforated water injectors. The injectivity model, considering both internal and external filtration, fitted the history data very well and allowed a comprehensive analysis of injectivity decline. The simulations revealed that, after the perforations filling, the injectivity decline rate becomes much more intensive. Therefore, the time necessary for perforations filling is an important variable on work over planning. (author)

  16. Performance of positive ion based high power ion source of EAST neutral beam injector

    Science.gov (United States)

    Hu, Chundong; Xie, Yahong; Xie, Yuanlai; Liu, Sheng; Xu, Yongjian; Liang, Lizhen; Jiang, Caichao; Li, Jun; Liu, Zhimin

    2016-02-01

    The positive ion based source with a hot cathode based arc chamber and a tetrode accelerator was employed for a neutral beam injector on the experimental advanced superconducting tokamak (EAST). Four ion sources were developed and each ion source has produced 4 MW @ 80 keV hydrogen beam on the test bed. 100 s long pulse operation with modulated beam has also been tested on the test bed. The accelerator was upgraded from circular shaped to diamond shaped in the latest two ion sources. In the latest campaign of EAST experiment, four ion sources injected more than 4 MW deuterium beam with beam energy of 60 keV into EAST.

  17. GANIL Workshop on Ion Sources; Journees Sources d'Ions

    Energy Technology Data Exchange (ETDEWEB)

    Leroy, Renan [Grand Accelerateur National d' Ions Lourds (GANIL), 14 - Caen (France)

    1999-07-01

    The proceedings of the GANIL Workshop on Ion Sources held at GANIL - Caen on 18-19 March 1999 contains 13 papers aiming at improving the old source operation and developing new types of sources for nuclear research and studies of ion physics. A number of reports are devoted to applications like surface treatment, ion implantation or fusion injection. The 1+{yields}n+ transformation, charged particle transport in ECR sources, addition of cesium and xenon in negative ion sources and other basic issues in ion sources are also addressed.

  18. Inverted battery design as ion generator for interfacing with biosystems

    Science.gov (United States)

    Wang, Chengwei; Fu, Kun (Kelvin); Dai, Jiaqi; Lacey, Steven D.; Yao, Yonggang; Pastel, Glenn; Xu, Lisha; Zhang, Jianhua; Hu, Liangbing

    2017-07-01

    In a lithium-ion battery, electrons are released from the anode and go through an external electronic circuit to power devices, while ions simultaneously transfer through internal ionic media to meet with electrons at the cathode. Inspired by the fundamental electrochemistry of the lithium-ion battery, we envision a cell that can generate a current of ions instead of electrons, so that ions can be used for potential applications in biosystems. Based on this concept, we report an `electron battery' configuration in which ions travel through an external circuit to interact with the intended biosystem whereas electrons are transported internally. As a proof-of-concept, we demonstrate the application of the electron battery by stimulating a monolayer of cultured cells, which fluoresces a calcium ion wave at a controlled ionic current. Electron batteries with the capability to generate a tunable ionic current could pave the way towards precise ion-system control in a broad range of biological applications.

  19. Microfluidic system with integrated microinjector for automated Drosophila embryo injection.

    Science.gov (United States)

    Delubac, Daniel; Highley, Christopher B; Witzberger-Krajcovic, Melissa; Ayoob, Joseph C; Furbee, Emily C; Minden, Jonathan S; Zappe, Stefan

    2012-11-21

    Drosophila is one of the most important model organisms in biology. Knowledge derived from the recently sequenced 12 genomes of various Drosophila species can today be combined with the results of more than 100 years of research to systematically investigate Drosophila biology at the molecular level. In order to enable automated, high-throughput manipulation of Drosophila embryos, we have developed a microfluidic system based on a Pyrex-silicon-Pyrex sandwich structure with integrated, surface-micromachined silicon nitride injector for automated injection of reagents. Our system automatically retrieves embryos from an external reservoir, separates potentially clustered embryos through a sheath flow mechanisms, passively aligns an embryo with the integrated injector through geometric constraints, and pushes the embryo onto the injector through flow drag forces. Automated detection of an embryo at injection position through an external camera triggers injection of reagents and subsequent ejection of the embryo to an external reservoir. Our technology can support automated screens based on Drosophila embryos as well as creation of transgenic Drosophila lines. Apart from Drosophila embryos, the layout of our system can be easily modified to accommodate injection of oocytes, embryos, larvae, or adults of other species and fills an important technological gap with regard to automated manipulation of multicellular organisms.

  20. 21 Tesla Fourier Transform Ion Cyclotron Resonance Mass Spectrometer: A National Resource for Ultrahigh Resolution Mass Analysis.

    Science.gov (United States)

    Hendrickson, Christopher L; Quinn, John P; Kaiser, Nathan K; Smith, Donald F; Blakney, Greg T; Chen, Tong; Marshall, Alan G; Weisbrod, Chad R; Beu, Steven C

    2015-09-01

    We describe the design and initial performance of the first 21 tesla Fourier transform ion cyclotron resonance (FT-ICR) mass spectrometer. The 21 tesla magnet is the highest field superconducting magnet ever used for FT-ICR and features high spatial homogeneity, high temporal stability, and negligible liquid helium consumption. The instrument includes a commercial dual linear quadrupole trap front end that features high sensitivity, precise control of trapped ion number, and collisional and electron transfer dissociation. A third linear quadrupole trap offers high ion capacity and ejection efficiency, and rf quadrupole ion injection optics deliver ions to a novel dynamically harmonized ICR cell. Mass resolving power of 150,000 (m/Δm(50%)) is achieved for bovine serum albumin (66 kDa) for a 0.38 s detection period, and greater than 2,000,000 resolving power is achieved for a 12 s detection period. Externally calibrated broadband mass measurement accuracy is typically less than 150 ppb rms, with resolving power greater than 300,000 at m/z 400 for a 0.76 s detection period. Combined analysis of electron transfer and collisional dissociation spectra results in 68% sequence coverage for carbonic anhydrase. The instrument is part of the NSF High-Field FT-ICR User Facility and is available free of charge to qualified users.

  1. Alfven eigenmode structure during off-axis neutral beam injection

    NARCIS (Netherlands)

    Tobias, B.; Bass, E. M.; Classen, I.G.J.; Domier, C.W.; Grierson, B. A.; Heidbrink, W. W.; N C Luhmann Jr.,; Nazikian, R.; Park, H. K.; Spong, D. A.; VanZeeland, M. A.

    2012-01-01

    The spatial structure of Alfven eigenmodes on the DIII-D tokamak is compared for contrasting fast ion deposition profiles resulting from on- and off-axis neutral beam injection (NBI). In both cases, poloidal mode rotation and eigenmode twist, or radial phase variation, are correlated with the direct

  2. Laser Ablation Plasma Injection into the Frankfurt 14 GHz ECRIS

    CERN Document Server

    Mironov, V; Runkel, S; Schmidt, L; Shirkov, G D; Stiebing, K E; Schmidt-Böcking, H; Schempp, A

    1999-01-01

    A Q-switched YAG:Nd3+ laser was used to evaporate a metal (Cd) target mounted close to a biased disk in the vacuum chamber of the 14 GHz Frankfurt ECRIS. The formation of the laser ablation plasma and the pulsed injection of neutral particles into ECR plasma resulting from the evaporation were studied in order to optimise the production of metal-ion beams and to perform diagnostics of the ECR plasma. The pulsed highly charged Cadmium ion beams were detected under the injection of neutral atoms of Cadmium into an Argon ECR discharge. The ionisation and confinements times for these ions were determined by using time-resolved spectroscopy of the charge state spectra. At the moment of the Cadmium injection, a pulsed increase of the Argon beam currents was detected, which is attributed to changes of the plasma potential. The amplitudes of these pulses are comparable with afterglow currents. Further investigations may provide a chance to use this effect for the injection of ion beams into the pulsed accelerators.

  3. External exposure in radionuclide therapy with 153 Sm

    Energy Technology Data Exchange (ETDEWEB)

    Rezio, M.T.; Vieira, M.R. [Instituto Portugues Oncologia de Francisco Gentil, CROL, Lisboa (Portugal)

    2006-07-01

    Full text of publication follows: Aim: The radiopharmaceutical 153 Sm is an beta emitter used in metastatic bone pain palliation. The prescribed activity is 37 MBq/kg body weight.. The aim of this study is to measure the dose rate of the patients during 4 to 6 hours after 153 Sm - E.D.T.M.P. administration in order to prevent external exposure of nursing staff, family members and general public. Material and Methods: Twelve patients were treated with 153 Sm in our department. External exposure rates( {mu}Sv/h) at different times and at one meter were measured, with a Geiger-Muller detector. Results: The mean dose rate at one meter was 12 {mu}Sv/h, one hour after injection and 3{mu} Sv/h, 6 hours after injection. Conclusion: The policy in our department is to keep the patient in the hospital 4-6 h, due to the risk of contamination. Based on our results, the external exposure of the nursing staff, family members and the general public is very low, in agreement with other studies. (authors)

  4. Faraday-cup-type lost fast ion detector on Heliotron J

    Science.gov (United States)

    Yamamoto, S.; Ogawa, K.; Isobe, M.; Darrow, D. S.; Kobayashi, S.; Nagasaki, K.; Okada, H.; Minami, T.; Kado, S.; Ohshima, S.; Weir, G. M.; Nakamura, Y.; Konoshima, S.; Kemmochi, N.; Ohtani, Y.; Mizuuchi, T.

    2016-11-01

    A Faraday-cup type lost-fast ion probe (FLIP) has been designed and installed in Heliotron J for the purpose of the studies of interaction between fast ions and MHD instabilities. The FLIP can measure the co-going fast ions whose energy is in the range of 1.7-42.5 keV (proton) and pitch angle of 90∘-140∘, especially for fast ions having the injection energy of neutral beam injection (NBI). The FLIP successfully measured the re-entering passing ions and trapped lost-fast ions caused by fast-ion-driven energetic particle modes in NBI heated plasmas.

  5. Faraday-cup-type lost fast ion detector on Heliotron J.

    Science.gov (United States)

    Yamamoto, S; Ogawa, K; Isobe, M; Darrow, D S; Kobayashi, S; Nagasaki, K; Okada, H; Minami, T; Kado, S; Ohshima, S; Weir, G M; Nakamura, Y; Konoshima, S; Kemmochi, N; Ohtani, Y; Mizuuchi, T

    2016-11-01

    A Faraday-cup type lost-fast ion probe (FLIP) has been designed and installed in Heliotron J for the purpose of the studies of interaction between fast ions and MHD instabilities. The FLIP can measure the co-going fast ions whose energy is in the range of 1.7-42.5 keV (proton) and pitch angle of 90(∘)-140(∘), especially for fast ions having the injection energy of neutral beam injection (NBI). The FLIP successfully measured the re-entering passing ions and trapped lost-fast ions caused by fast-ion-driven energetic particle modes in NBI heated plasmas.

  6. A Device Model for Polymer Light-Emitting Diodes with Mobile Ions

    NARCIS (Netherlands)

    Jong, M.J.M. de; Blom, P.W.M.

    1996-01-01

    A model is presented for the device operation of a polymer light-emitting diode (PLED) with mobile ions. It is calculated that the low efficiency of a PLED with a high injection barrier increases as the ions migrate.

  7. Behavior of Compact Toroid in the External Magnetic Fields

    Science.gov (United States)

    Fukumoto, N.; Ioroi, A.; Nagata, M.; Uyama, T.

    1999-11-01

    We have investigated the possibility of refueling and density control of tokamak plasmas by the spheromak-type Compact Toroid (CT) injection in the JFT-2M tokamak in collaboration with JAERI. We demonstrated the CT injection into OH plasmas and observed the core penetration at B_T=0.8 T. The tokamak electron density increased ~0.2× 10^19m-3 at a rate of 2× 10^21m-3/s. We also observed the decrease of the CT velocity by the external magnetic field of the tokamak, which is applied across the CT acceleration region. We have examined the behavior of the CT translated in the external fields B_ext using the magnetic probes and the fast framing camera at Himeji Inst. of tech.. CT plasma in the acceleration region is deformed by the Lorentz force of Jg × B_ext, where Jg is the gun current for CT acceleration. The magnetic field structures of a long CT in the drift region has been revealed to be the mixed relaxed state of m=0 and m=1. Results from CT acceleration and injection in a transverse field will be presented.

  8. A grating-coupled external cavity InAs/InP quantum dot laser with 85-nm tuning range

    Science.gov (United States)

    Wei, Heng; Jin, Peng; Luo, Shuai; Ji, Hai-Ming; Yang, Tao; Li, Xin-Kun; Wu, Jian; An, Qi; Wu, Yan-Hua; Chen, Hong-Mei; Wang, Fei-Fei; Wu, Ju; Wang, Zhan-Guo

    2013-09-01

    The optical performance of a grating-coupled external cavity laser based on InAs/InP quantum dots is investigated. Continuous tuning from 1391 nm to 1468 nm is realized at an injection current of 1900 mA. With the injection current increasing to 2300 mA, the tuning is blue shifted to some extent to the range from 1383 nm to 1461 nm. By combining the effect of the injection current with the grating tuning, the total tuning bandwidth of the external cavity quantum-dot laser can reach up to 85 nm. The dependence of the threshold current on the tuning wavelength is also presented.

  9. Neutralization principles for the Extraction and Transport of Ion Beams

    CERN Document Server

    Riege, H

    2000-01-01

    The strict application of conventional extraction techniques of ion beams from a plasma source is characterized by a natural intensity limit determined by space charge.The extracted current may be enhanced far beyond this limit by neutralizing the space charge of the extracted ions in the first extraction gap of the source with electrons injected from the opposite side. The transverse and longitudinal emittances of a neutralized ion beam, hence its brightness, are preserved. Results of beam compensation experiments, which have been carried out with a laser ion source, are resumed for proposing a general scheme of neutralizing ion sources and their adjacent low-energy beam transport channels with electron beams. Many technical applications of high-mass ion beam neutralization technology may be identified: the enhancement of ion source output for injection into high-intensity, low-and high-energy accelerators, or ion thrusters in space technology, for the neutral beams needed for plasma heating of magnetic conf...

  10. The DCU laser ion source.

    Science.gov (United States)

    Yeates, P; Costello, J T; Kennedy, E T

    2010-04-01

    Laser ion sources are used to generate and deliver highly charged ions of various masses and energies. We present details on the design and basic parameters of the DCU laser ion source (LIS). The theoretical aspects of a high voltage (HV) linear LIS are presented and the main issues surrounding laser-plasma formation, ion extraction and modeling of beam transport in relation to the operation of a LIS are detailed. A range of laser power densities (I approximately 10(8)-10(11) W cm(-2)) and fluences (F=0.1-3.9 kJ cm(-2)) from a Q-switched ruby laser (full-width half-maximum pulse duration approximately 35 ns, lambda=694 nm) were used to generate a copper plasma. In "basic operating mode," laser generated plasma ions are electrostatically accelerated using a dc HV bias (5-18 kV). A traditional einzel electrostatic lens system is utilized to transport and collimate the extracted ion beam for detection via a Faraday cup. Peak currents of up to I approximately 600 microA for Cu(+) to Cu(3+) ions were recorded. The maximum collected charge reached 94 pC (Cu(2+)). Hydrodynamic simulations and ion probe diagnostics were used to study the plasma plume within the extraction gap. The system measured performance and electrodynamic simulations indicated that the use of a short field-free (L=48 mm) region results in rapid expansion of the injected ion beam in the drift tube. This severely limits the efficiency of the electrostatic lens system and consequently the sources performance. Simulations of ion beam dynamics in a "continuous einzel array" were performed and experimentally verified to counter the strong space-charge force present in the ion beam which results from plasma extraction close to the target surface. Ion beam acceleration and injection thus occur at "high pressure." In "enhanced operating mode," peak currents of 3.26 mA (Cu(2+)) were recorded. The collected currents of more highly charged ions (Cu(4+)-Cu(6+)) increased considerably in this mode of operation.

  11. Injection-controlled laser resonator

    Science.gov (United States)

    Chang, J.J.

    1995-07-18

    A new injection-controlled laser resonator incorporates self-filtering and self-imaging characteristics with an efficient injection scheme. A low-divergence laser signal is injected into the resonator, which enables the injection signal to be converted to the desired resonator modes before the main laser pulse starts. This injection technique and resonator design enable the laser cavity to improve the quality of the injection signal through self-filtering before the main laser pulse starts. The self-imaging property of the present resonator reduces the cavity induced diffraction effects and, in turn, improves the laser beam quality. 5 figs.

  12. SPS injection kicker magnet

    CERN Multimedia

    1975-01-01

    One of the first-generation SPS injection kicker magnets, view of the complete tank. First proton beam from the PS was injected into the SPS in 1976, at a beam momentum of 10 GeV/c. These kickers served until the end of 1979 and were replaced at the beginning of 1980 by stronger ones, in preparation for the SPS as a proton-antiproton collider. For this, transfer momentum from the PS to the SPS was raised to 26 GeV/c, so as to avoid acceleration of the dense p and pbar bunches through SPS transition energy. Bearded Roland Tröhler is at the left, Giacomo Busetta smiles at the right. See also 7502073X, 7502074X and Annual Report 1975, 162.

  13. PS injection area

    CERN Multimedia

    1974-01-01

    Looking against the direction of protons in the main ring (left): the beam coming from the linac 1 either goes to the booster (on the right) or is deflected towards the PS to be directly injected into section 26 (facing the camera). Also shown the start of the TT2 line, ejected from straight section 16 to go towards the ISR passing over the beam line from the linac. (see Photo Archive 7409009)

  14. Optimal Auctions with Financial Externalities

    NARCIS (Netherlands)

    Maasland, E.; Onderstal, A.M.

    2002-01-01

    We construct optimal auctions when bidders face financial externalities.In a Coasean World, in which the seller cannot prevent a perfect resale market, nor withhold the object, the lowest-price all-pay auction is optimal.In a Myersonean World, in which the seller can both prevent resale after the au

  15. Organizing for External Knowledge Sourcing

    DEFF Research Database (Denmark)

    Rabbiosi, Larissa; Reichstein, Toke

    2011-01-01

    The aim of this article is to provide an introduction to the special issue. We briefly consider the external knowledge sourcing and organizing for innovation literatures, which offer a background for the special issue, and we highlight their mutual dialogue. We then illustrate the main findings...

  16. Measuring Externalities in Program Evaluation

    NARCIS (Netherlands)

    Janssens, Wendy

    2005-01-01

    Impact evaluations of development programmes usually focus on a comparison of participants with a control group. However, if the programme generates externalities for non-participants such an approach will capture only part of the programme's impact. Based on a unique large-scale quantitative survey

  17. Lupus vulgaris of external nose.

    Science.gov (United States)

    Bhandary, Satheesh Kumar; Ranganna, B Usha

    2008-12-01

    Lupus vulgaris is the commonest form of cutaneous tuberculosis which commonly involve trunk and buttocks. Lupus vulgaris affecting nose and face, are rarely reported in India. This study reports an unusual case of lupus vulgaris involving the external nose that showed dramatic outcome after six months of anti- tubercular treatment.

  18. Matchings with Externalities and Attitudes

    DEFF Research Database (Denmark)

    Branzei, Simina; Michalak, Tomasz; Rahwan, Talal;

    2013-01-01

    Two-sided matchings are an important theoretical tool used to model markets and social interactions. In many real-life problems the utility of an agent is influenced not only by their own choices, but also by the choices that other agents make. Such an influence is called an externality. Whereas ...

  19. Post-external dacryocystorhinostomy lagophthalmos.

    Science.gov (United States)

    Odat, Thabit A; Odat, Haitham A; Khraisat, Heba; Odat, Mohannad A; Alzoubi, Firas Q

    2015-06-01

    To describe lagophthalmos and eyelid closure abnormality after external dacryocystorhinostomy (DCR). A retrospective review of medical records and postoperative photographs of 79 patients who underwent external DCR for nasolacrimal duct obstruction and developed eyelid closure abnormality and lagophthalmos with or without exposure keratopathy was conducted. Collected data included age, sex, indication for surgery, laterality, length and type of incision, length of follow-up duration, presence of punctate epithelial keratopathy, and time for resolution of eyelid closure abnormalities. Twenty-seven patients with 28 external dacryocystorhinostomy had postoperative eyelid closure abnormalities. Male to female ratio was 1:6. The mean age was 40.1 years (range 9-80 years). All surgeries were performed through diagonal skin incision. Lagophthalmos involving the medial third of the palpebral fissure was noticed in 28.6 % of cases. All patients had hypometric blink mainly of the upper eyelid. One patient had punctate epithelial keratopathy. Resolution of lagophthalmos was noticed over a period of 1-5 weeks with an average of 3 weeks. None of the patients continued to have residual hypometric blink or punctate keratopathy at the last follow-up time. The mean follow-up period was 4.2 months (range 3-6 months). Eyelid closure abnormality and lagophthalmos after external DCR are underestimated problems. Spontaneous resolution is seen in all cases weeks to months after surgery.

  20. Femoral Reconstruction Using External Fixation

    Directory of Open Access Journals (Sweden)

    Yevgeniy Palatnik

    2011-01-01

    Full Text Available Background. The use of an external fixator for the purpose of distraction osteogenesis has been applied to a wide range of orthopedic problems caused by such diverse etiologies as congenital disease, metabolic conditions, infections, traumatic injuries, and congenital short stature. The purpose of this study was to analyze our experience of utilizing this method in patients undergoing a variety of orthopedic procedures of the femur. Methods. We retrospectively reviewed our experience of using external fixation for femoral reconstruction. Three subgroups were defined based on the primary reconstruction goal lengthening, deformity correction, and repair of nonunion/bone defect. Factors such as leg length discrepancy (LLD, limb alignment, and external fixation time and complications were evaluated for the entire group and the 3 subgroups. Results. There was substantial improvement in the overall LLD, femoral length discrepancy, and limb alignment as measured by mechanical axis deviation (MAD and lateral distal femoral angle (LDFA for the entire group as well as the subgroups. Conclusions. The Ilizarov external fixator allows for decreased surgical exposure and preservation of blood supply to bone, avoidance of bone grafting and internal fixation, and simultaneous lengthening and deformity correction, making it a very useful technique for femoral reconstruction.