WorldWideScience

Sample records for expressing olap operators

  1. Improving Expression Power in Modeling OLAP Hierarchies

    Science.gov (United States)

    Malinowski, Elzbieta

    Data warehouses and OLAP systems form an integral part of modern decision support systems. In order to exploit both systems to their full capabilities hierarchies must be clearly defined. Hierarchies are important in analytical applications, since they provide users with the possibility to represent data at different abstraction levels. However, even though there are different kinds of hierarchies in real-world applications and some are already implemented in commercial tools, there is still a lack of a well-accepted conceptual model that allows decision-making users express their analysis needs. In this paper, we show how the conceptual multidimensional model can be used to facilitate the representation of complex hierarchies in comparison to their representation in the relational model and commercial OLAP tool, using as an example Microsoft Analysis Services.

  2. Online Analytical Processing (OLAP: A Fast and Effective Data Mining Tool for Gene Expression Databases

    Directory of Open Access Journals (Sweden)

    Alkharouf Nadim W.

    2005-01-01

    Full Text Available Gene expression databases contain a wealth of information, but current data mining tools are limited in their speed and effectiveness in extracting meaningful biological knowledge from them. Online analytical processing (OLAP can be used as a supplement to cluster analysis for fast and effective data mining of gene expression databases. We used Analysis Services 2000, a product that ships with SQLServer2000, to construct an OLAP cube that was used to mine a time series experiment designed to identify genes associated with resistance of soybean to the soybean cyst nematode, a devastating pest of soybean. The data for these experiments is stored in the soybean genomics and microarray database (SGMD. A number of candidate resistance genes and pathways were found. Compared to traditional cluster analysis of gene expression data, OLAP was more effective and faster in finding biologically meaningful information. OLAP is available from a number of vendors and can work with any relational database management system through OLE DB.

  3. Online analytical processing (OLAP): a fast and effective data mining tool for gene expression databases.

    Science.gov (United States)

    Alkharouf, Nadim W; Jamison, D Curtis; Matthews, Benjamin F

    2005-06-30

    Gene expression databases contain a wealth of information, but current data mining tools are limited in their speed and effectiveness in extracting meaningful biological knowledge from them. Online analytical processing (OLAP) can be used as a supplement to cluster analysis for fast and effective data mining of gene expression databases. We used Analysis Services 2000, a product that ships with SQLServer2000, to construct an OLAP cube that was used to mine a time series experiment designed to identify genes associated with resistance of soybean to the soybean cyst nematode, a devastating pest of soybean. The data for these experiments is stored in the soybean genomics and microarray database (SGMD). A number of candidate resistance genes and pathways were found. Compared to traditional cluster analysis of gene expression data, OLAP was more effective and faster in finding biologically meaningful information. OLAP is available from a number of vendors and can work with any relational database management system through OLE DB.

  4. Achieving Adaptivity For OLAP-XML Federations

    DEFF Research Database (Denmark)

    Pedersen, D.; Pedersen, Torben Bach

    2003-01-01

    Motivated by the need for more flexible OLAP systems, this paper presents the results of work on logical integration of external data in OLAP databases, carried out in cooperation between the Danish OLAP client vendor \\targit and Aalborg University. Flexibility is ensured by supporting XML......'s ability to adapt to changes in its surroundings. This paper describes the potential problems that may interrupt the operation of the integration system, in particular those caused by the often autonomous and unreliable nature of external XML data sources, and methods for handling these problems...

  5. [General principles of database storage operations with emphasis on OLAP reports].

    Science.gov (United States)

    Borkowski, Włodzimierz; Mielniczuk, Hanna

    2004-01-01

    In article general principles and features of data warehouse were presented in particular of OLAP reports. The data warehouse was built using Oracle tools. The repository was filled with death records from Central Office of Statistics. Various features adequate for epidemiological analyses have been discussed and illustrated like pivoting and rotating dimension, drilling on hierarchical data, reduction of dimensions. The possibility of specific for epidemiology indicators creation was shown. The need of implementation of data warehouses and OLAP reports in Polish healthcare was discussed. In comparison with traditional manner of analysis and presentation epidemiological facts OLAP reports give new perspectives.

  6. The Composite OLAP-Object Data Model

    Energy Technology Data Exchange (ETDEWEB)

    Pourabbas, Elaheh; Shoshani, Arie

    2005-12-07

    In this paper, we define an OLAP-Object model that combines the main characteristics of OLAP and Object data models in order to achieve their functionalities in a common framework. We classify three different object classes: primitive, regular and composite. Then, we define a query language which uses the path concept in order to facilitate data navigation and data manipulation. The main feature of the proposed language is an anchor. It allows us to fix dynamically an object class (primitive, regular or composite) along the paths over the OLAP-Object data model for expressing queries. The queries can be formulated on objects, composite objects and combination of both. The power of the proposed query language is investigated through multiple query examples. The semantic of different clauses and syntax of the proposed language are investigated.

  7. Building OLAP Catalog

    Directory of Open Access Journals (Sweden)

    Mihaela MUNTEAN

    2006-01-01

    Full Text Available The Oracle OLAP option of Oracle Database 10g Enterprise Edition provides advanced analytic features to help us to summarize, analyze and calculate data faster than standard SQL. In this article I discussed about the CWM2, a set of PL/SQL packages which are using to create the OLAP Catalog metadata for an analytic workspace. BI Beans applications query OLAP Catalog metadata.

  8. QB2OLAP : enabling OLAP on statistical linked open data

    OpenAIRE

    Varga, Jovan; Etcheverry, Lorena; Vaisman, Alejandro; Romero Moral, Óscar; Bach Pedersen, Torben; Thomsen, Christian

    2016-01-01

    Publication and sharing of multidimensional (MD) data on the Semantic Web (SW) opens new opportunities for the use of On-Line Analytical Processing (OLAP). The RDF Data Cube (QB) vocabulary, the current standard for statistical data publishing, however, lacks key MD concepts such as dimension hierarchies and aggregate functions. QB4OLAP was proposed to remedy this. However, QB4OLAP requires extensive manual annotation and users must still write queries in SPARQL, the standard query language f...

  9. The OLAP-XML Federation System

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    2006-01-01

    We present the logical “OLAP-XML Federation System” that enables the external data available in XML format to be used as virtual dimensions. Unlike the complex and time-consuming physical integration of OLAP and external data in current OLAP systems, our system makes OLAP queries referencing fast...

  10. Explanatory analytics in OLAP

    NARCIS (Netherlands)

    Caron, E.A.M.; Daniëls, H.A.M.

    2013-01-01

    In this paper the authors describe a method to integrate explanatory business analytics in OLAP information systems. This method supports the discovery of exceptional values in OLAP data and the explanation of such values by giving their underlying causes. OLAP applications offer a support tool for

  11. Applying GRID Technologies to XML Based OLAP Cube Construction

    CERN Document Server

    Niemi, Tapio Petteri; Nummenmaa, J; Thanisch, P

    2002-01-01

    On-Line Analytical Processing (OLAP) is a powerful method for analysing large data warehouse data. Typically, the data for an OLAP database is collected from a set of data repositories such as e.g. operational databases. This data set is often huge, and it may not be known in advance what data is required and when to perform the desired data analysis tasks. Sometimes it may happen that some parts of the data are only needed occasionally. Therefore, storing all data to the OLAP database and keeping this database constantly up-to-date is not only a highly demanding task but it also may be overkill in practice. This suggests that in some applications it would be more feasible to form the OLAP cubes only when they are actually needed. However, the OLAP cube construction can be a slow process. Thus, we present a system that applies Grid technologies to distribute the computation. As the data sources may well be heterogeneous, we propose an XML language for data collection. The user's definition for a OLAP new cube...

  12. Hierarchical reorganization of dimensions in OLAP visualizations.

    Science.gov (United States)

    Lafon, Sébastien; Bouali, Fatma; Guinot, Christiane; Venturini, Gilles

    2013-11-01

    In this paper, we propose a new method for the visual reorganization of online analytical processing (OLAP) cubes that aims at improving their visualization. Our method addresses dimensions with hierarchically organized members. It uses a genetic algorithm that reorganizes k-ary trees. Genetic operators perform permutations of subtrees to optimize a visual homogeneity function. We propose several ways to reorganize an OLAP cube depending on which set of members is selected for the reorganization: all of the members, only the displayed members, or the members at a given level (level by level approach). The results that are evaluated by using optimization criteria show that our algorithm has a reliable performance even when it is limited to 1 minute runs. Our algorithm was integrated in an interactive 3D interface for OLAP. A user study was conducted to evaluate our approach with users. The results highlight the usefulness of reorganization in two OLAP tasks.

  13. QB2OLAP

    DEFF Research Database (Denmark)

    Varga, Jovan; Etcheverry, Lorena; Vaisman, Alejandro

    2016-01-01

    Publication and sharing of multidimensional (MD) data on the Semantic Web (SW) opens new opportunities for the use of On-Line Analytical Processing (OLAP). The RDF Data Cube (QB) vocabulary, the current standard for statistical data publishing, however, lacks key MD concepts such as dimension...... the QB4OLAP semantics and is automatically translated to SPARQL....

  14. Extending OLAP Querying to External Object

    DEFF Research Database (Denmark)

    Pedersen, Torben Bach; Shoshani, Arie; Gu, Junmin

    On-Line Analytical Processing (OLAP) systems based on a dimensional view of data have found widespread use in business applications and are being used increasingly in non-standard applications. These systems provide good performance and ease-of-use. However, the complex structures and relationships...... inherent in data in nonstandard applications are not accommodated well by OLAP systems. In contrast, object database systems are built to handle such complexity, but do not support OLAP-type querying well. This paper presents the concepts and techniques underlying a flexible, multi-model federated system...... that enables OLAP users to exploit simultaneously the features of OLAP and object systems. The system allows data to be handled using the most appropriate data model and technology: OLAP systems for dimensional data and object database systems for more complex, general data. Additionally, physical data...

  15. CAMS: OLAPing Multidimensional Data Streams Efficiently

    Science.gov (United States)

    Cuzzocrea, Alfredo

    In the context of data stream research, taming the multidimensionality of real-life data streams in order to efficiently support OLAP analysis/mining tasks is a critical challenge. Inspired by this fundamental motivation, in this paper we introduce CAMS (C ube-based A cquisition model for M ultidimensional S treams), a model for efficiently OLAPing multidimensional data streams. CAMS combines a set of data stream processing methodologies, namely (i) the OLAP dimension flattening process, which allows us to obtain dimensionality reduction of multidimensional data streams, and (ii) the OLAP stream aggregation scheme, which aggregates data stream readings according to an OLAP-hierarchy-based membership approach. We complete our analytical contribution by means of experimental assessment and analysis of both the efficiency and the scalability of OLAPing capabilities of CAMS on synthetic multidimensional data streams. Both analytical and experimental results clearly connote CAMS as an enabling component for next-generation Data Stream Management Systems.

  16. Microsoft SQL Server OLAP Solution - A Survey

    OpenAIRE

    Badiozamany, Sobhan

    2010-01-01

    Microsoft SQL Server 2008 offers technologies for performing On-Line Analytical Processing (OLAP), directly on data stored in data warehouses, instead of moving the data into some offline OLAP tool. This brings certain benefits, such as elimination of data copying and better integration with the DBMS compared with off-line OLAP tools. This report reviews SQL Server support for OLAP, solution architectures, tools and components involved. Standard storage options are discussed but the focus of ...

  17. Algebra-Based Optimization of XML-Extended OLAP Queries

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    2006-01-01

    In today’s OLAP systems, integrating fast changing data physically into a cube is complex and time-consuming. Our solution, the “OLAP-XML Federation System,” makes it possible to reference the fast changing data in XML format in OLAP queries without physical integration. In this paper, we introduce...

  18. Algebra-Based Optimization of XML-Extended OLAP Queries

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    In today’s OLAP systems, integrating fast changing data, e.g., stock quotes, physically into a cube is complex and time-consuming. The widespread use of XML makes it very possible that this data is available in XML format on the WWW; thus, making XML data logically federated with OLAP systems...... is desirable. This report presents a complete foundation for such OLAP-XML federations. This includes a prototypical query engine, a simplified query semantics based on previous work, and a complete physical algebra which enables precise modeling of the execution tasks of an OLAP-XML query. Effective algebra...

  19. A Conceptual Modeling Approach for OLAP Personalization

    Science.gov (United States)

    Garrigós, Irene; Pardillo, Jesús; Mazón, Jose-Norberto; Trujillo, Juan

    Data warehouses rely on multidimensional models in order to provide decision makers with appropriate structures to intuitively analyze data with OLAP technologies. However, data warehouses may be potentially large and multidimensional structures become increasingly complex to be understood at a glance. Even if a departmental data warehouse (also known as data mart) is used, these structures would be also too complex. As a consequence, acquiring the required information is more costly than expected and decision makers using OLAP tools may get frustrated. In this context, current approaches for data warehouse design are focused on deriving a unique OLAP schema for all analysts from their previously stated information requirements, which is not enough to lighten the complexity of the decision making process. To overcome this drawback, we argue for personalizing multidimensional models for OLAP technologies according to the continuously changing user characteristics, context, requirements and behaviour. In this paper, we present a novel approach to personalizing OLAP systems at the conceptual level based on the underlying multidimensional model of the data warehouse, a user model and a set of personalization rules. The great advantage of our approach is that a personalized OLAP schema is provided for each decision maker contributing to better satisfy their specific analysis needs. Finally, we show the applicability of our approach through a sample scenario based on our CASE tool for data warehouse development.

  20. Vers une intégration de la connaissance dans l’analyse exploratoire des cubes OLAP

    Directory of Open Access Journals (Sweden)

    Sami Naouali

    2005-10-01

    Full Text Available This paper presents a general framework allowing a tight coupling between data warehousing and data mining capabilities in a uniform and integrated way. The proposed approach consists in integra­ting knowledge into data warehouses and especially in OLAP cubes exploration. This integration aims to make the OLAP process guided both by multidimensional data and knowledge. A multidimensional structure is then proposed to support data and knowledge. We propose also a set of analytical operators and multidimensional data mining operators. To illustrate the proposed approach, a real OLAP cube built to understand the behaviour of users navigating on the Web is proposed and used to show by concrete examples the interest of such extension of data warehouses.

  1. Preference-Based Recommendations for OLAP Analysis

    Science.gov (United States)

    Jerbi, Houssem; Ravat, Franck; Teste, Olivier; Zurfluh, Gilles

    This paper presents a framework for integrating OLAP and recommendations. We focus on the anticipatory recommendation process that assists the user during his OLAP analysis by proposing to him the forthcoming analysis step. We present a context-aware preference model that matches decision-makers intuition, and we discuss a preference-based approach for generating personalized recommendations.

  2. OLAP TECHNOLOGY AS DECISION-MAKING SUPPORT TOOL

    Directory of Open Access Journals (Sweden)

    D. V. Akushko

    2017-01-01

    Full Text Available The present article discloses the basic principles of work with OLAP technologies, shows key features in comparison with traditional systems of the reporting. The simplified structure of an OLAP cube for the analysis of cost of products of the steelsmelting shop is considered.

  3. Integrating XML Data in the TARGIT OLAP System

    DEFF Research Database (Denmark)

    Pedersen, Dennis; Pedersen, Jesper; Pedersen, Torben Bach

    2004-01-01

    This paper presents work on logical integration of OLAP and XML data sources, carried out in cooperation between TARGIT, a Danish OLAP client vendor, and Aalborg University. A prototype has been developed that allows XML data on the WWW to be used as dimensions and measures in the OLAP system...... the ability to use XML data as measures, as well as a novel multigranular data model and query language that formalizes and extends the TARGIT data model and query language....

  4. RoK: Roll-Up with the K-Means Clustering Method for Recommending OLAP Queries

    Science.gov (United States)

    Bentayeb, Fadila; Favre, Cécile

    Dimension hierarchies represent a substantial part of the data warehouse model. Indeed they allow decision makers to examine data at different levels of detail with On-Line Analytical Processing (OLAP) operators such as drill-down and roll-up. The granularity levels which compose a dimension hierarchy are usually fixed during the design step of the data warehouse, according to the identified analysis needs of the users. However, in practice, the needs of users may evolve and grow in time. Hence, to take into account the users’ analysis evolution into the data warehouse, we propose to integrate personalization techniques within the OLAP process. We propose two kinds of OLAP personalization in the data warehouse: (1) adaptation and (2) recommendation.

  5. Using data warehousing and OLAP in public health care.

    Science.gov (United States)

    Hristovski, D; Rogac, M; Markota, M

    2000-01-01

    The paper describes the possibilities of using data warehousing and OLAP technologies in public health care in general and then our own experience with these technologies gained during the implementation of a data warehouse of outpatient data at the national level. Such a data warehouse serves as a basis for advanced decision support systems based on statistical, OLAP or data mining methods. We used OLAP to enable interactive exploration and analysis of the data. We found out that data warehousing and OLAP are suitable for the domain of public health and that they enable new analytical possibilities in addition to the traditional statistical approaches.

  6. Evaluating XML-Extended OLAP Queries Based on a Physical Algebra

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    2004-01-01

    is desirable. In this paper, we extend previous work on the logical federation of OLAP and XML data sources by presenting a simplified query semantics,a physical query algebra and a robust OLAP-XML query engine.Performance experiments with a prototypical implementation suggest that the performance for OLAP...

  7. Applying Olap Model On Public Finance Management

    OpenAIRE

    Dorde Pavlovic; Branko Gledovic

    2011-01-01

    Budget control is derivate from one of the main functions of budget, that aims that the budget is control instrument of acquiring and pending of budget needs. OLAP model represents an instrument that finds its place in the budget planning process, executive phases of budget, accountancy, etc. There is a direct correlation between the OLAP model and public finance management process.

  8. An on-line advanced plant simulator (OLAPS)

    International Nuclear Information System (INIS)

    Samuels, J.W.

    1989-01-01

    A PC based on-line advanced plant simulator (OLAPS) for high quality simulations of Portland General Electric's Trojan Nuclear Facility is presented. OLAPS is designed to simulate the thermal-hydraulics of the primary system including core, steam generators, pumps, piping and pressurizer. The simulations are based on a five equation model that has two mass equations, two energy equations, two energy equations, and one momentum equation with a drift flux model to provide closure. A regionwise point reactor kinetics model is used to model the neutron kinetics in the core. The conservation equations, constitutive models and the numerical methods used to solve them are described. OLAPS results are compared with data from chapter 15 of the Trojan Nuclear Facility's final safety analysis report

  9. Multidimensional (OLAP) Analysis for Designing Dynamic Learning Strategy

    Science.gov (United States)

    Rozeva, A.; Deliyska, B.

    2010-10-01

    Learning strategy in an intelligent learning system is generally elaborated on the basis of assessment of the following factors: learner's time for reaction, content of the learning object, amount of learning material in a learning object, learning object specification, e-learning medium and performance control. Current work proposes architecture for dynamic learning strategy design by implementing multidimensional analysis model of learning factors. The analysis model concerns on-line analytical processing (OLAP) of learner's data structured as multidimensional cube. Main components of the architecture are analysis agent for performing the OLAP operations on learner data cube, adaptation generator and knowledge selection agent for performing adaptive navigation in the learning object repository. The output of the analysis agent is involved in dynamic elaboration of learning strategy that fits best to learners profile and behavior. As a result an adaptive learning path for individual learner and for learner groups is generated.

  10. Usability Evaluation of the Spatial OLAP Visualization and Analysis Tool (SOVAT).

    Science.gov (United States)

    Scotch, Matthew; Parmanto, Bambang; Monaco, Valerie

    2007-02-01

    Increasingly sophisticated technologies, such as On-Line Analytical Processing (OLAP) and Geospatial Information Systems (GIS), are being leveraged for conducting community health assessments (CHA). Little is known about the usability of OLAP and GIS interfaces with respect to CHA. We conducted an iterative usability evaluation of the Spatial OLAP Visualization and Analysis Tool (SOVAT), a software application that combines OLAP and GIS. A total of nine graduate students and six community health researchers were asked to think-aloud while completing five CHA questions using SOVAT. The sessions were analyzed after every three participants and changes to the interface were made based on the findings. Measures included elapsed time, answers provided, erroneous actions, and satisfaction. Traditional OLAP interface features were poorly understood by participants and combined OLAP-GIS features needed to be better emphasized. The results suggest that the changes made to the SOVAT interface resulted in increases in both usability and user satisfaction.

  11. Implementing OLAP Technology to Leverage Value of Supply Chain Management System

    Directory of Open Access Journals (Sweden)

    Ekananta Ekananta

    2012-01-01

    Full Text Available Supply chain refers to the flow of materials, information, money, and services from rawmaterial suppliers, through factories and warehouses, to the end users. The successful of company inthe business competition is highly depend on how well the company capability to optimize andmanage their supply chain process. ERP is an information technology solution that play the mainrole in the supply chain management with the aim to plan, organize, and optimize one or more of thesupply chain’s activities which is concentrate on supply chain efficiency.The recent development of Supply Chain Performance Management (SCPM Application, theOLAP based information technology solutions, will help supply chain managers to be more effectivein managing supply chain activities due to its capability to provide the planning and controllingfunction to achieve a better operation performance.This paper will describe the role of OLAP technology to leverage value of supply chainmanagement system by complement the ERP functions and also provide the descriptions of thetechnology framework and development methodology for Supply Chain Performance Management(SCPM Application.Keywords: Supply Chain Management, OLAP, Performance Management

  12. OLAP Cube Visualization of Hydrologic Data Catalogs

    Science.gov (United States)

    Zaslavsky, I.; Rodriguez, M.; Beran, B.; Valentine, D.; van Ingen, C.; Wallis, J. C.

    2007-12-01

    As part of the CUAHSI Hydrologic Information System project, we assemble comprehensive observations data catalogs that support CUAHSI data discovery services (WaterOneFlow services) and online mapping interfaces (e.g. the Data Access System for Hydrology, DASH). These catalogs describe several nation-wide data repositories that are important for hydrologists, including USGS NWIS and EPA STORET data collections. The catalogs contain a wealth of information reflecting the entire history and geography of hydrologic observations in the US. Managing such catalogs requires high performance analysis and visualization technologies. OLAP (Online Analytical Processing) cube, often called data cubes, is an approach to organizing and querying large multi-dimensional data collections. We have applied the OLAP techniques, as implemented in Microsoft SQL Server 2005, to the analysis of the catalogs from several agencies. In this initial report, we focus on the OLAP technology as applied to catalogs, and preliminary results of the analysis. Specifically, we describe the challenges of generating OLAP cube dimensions, and defining aggregations and views for data catalogs as opposed to observations data themselves. The initial results are related to hydrologic data availability from the observations data catalogs. The results reflect geography and history of available data totals from USGS NWIS and EPA STORET repositories, and spatial and temporal dynamics of available measurements for several key nutrient-related parameters.

  13. Examining the Impact of Culture and Human Elements on OLAP Tools Usefulness

    Science.gov (United States)

    Sharoupim, Magdy S.

    2010-01-01

    The purpose of the present study was to examine the impact of culture and human-related elements on the On-line Analytical Processing (OLAP) usability in generating decision-making information. The use of OLAP technology has evolved rapidly and gained momentum, mainly due to the ability of OLAP tools to examine and query large amounts of data sets…

  14. Optimized Data Indexing Algorithms for OLAP Systems

    Directory of Open Access Journals (Sweden)

    Lucian BORNAZ

    2010-12-01

    Full Text Available The need to process and analyze large data volumes, as well as to convey the information contained therein to decision makers naturally led to the development of OLAP systems. Similarly to SGBDs, OLAP systems must ensure optimum access to the storage environment. Although there are several ways to optimize database systems, implementing a correct data indexing solution is the most effective and less costly. Thus, OLAP uses indexing algorithms for relational data and n-dimensional summarized data stored in cubes. Today database systems implement derived indexing algorithms based on well-known Tree, Bitmap and Hash indexing algorithms. This is because no indexing algorithm provides the best performance for any particular situation (type, structure, data volume, application. This paper presents a new n-dimensional cube indexing algorithm, derived from the well known B-Tree index, which indexes data stored in data warehouses taking in consideration their multi-dimensional nature and provides better performance in comparison to the already implemented Tree-like index types.

  15. Evaluating XML-Extended OLAP Queries Based on a Physical Algebra

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    2006-01-01

    . In this paper, we extend previous work on the logical federation of OLAP and XML data sources by presenting a simplified query semantics, a physical query algebra and a robust OLAP-XML query engine as well as the query evaluation techniques. Performance experiments with a prototypical implementation suggest...

  16. Method and System for Making OLAP Hierarchies Summarisable

    DEFF Research Database (Denmark)

    2002-01-01

    Field of Invention: The present invention relates to computer databases, in particular to a method and system for transforming general OLAP hierarchies into summarizable hierarchies. This enables fast query response times for aggregation queries without excessive storage use even when the hierarc......Field of Invention: The present invention relates to computer databases, in particular to a method and system for transforming general OLAP hierarchies into summarizable hierarchies. This enables fast query response times for aggregation queries without excessive storage use even when...

  17. Diagnosis in the Olap Context

    NARCIS (Netherlands)

    E.A.M. Caron (Emiel); H.A.M. Daniels (Hennie)

    2004-01-01

    textabstractThe purpose of OLAP (On-Line Analytical Processing) systems is to provide a framework for the analysis of multidimensional data. Many tasks related to analysing multidimensional data and making business decisions are still carried out manually by analysts (e.g. financial analysts,

  18. OLAP – Online Analytical Processing

    Directory of Open Access Journals (Sweden)

    Azoumana Kamagate

    2013-07-01

    Full Text Available Este procesamiento analítico le da pautas al mundo empresarial, en permitir realizar análisis multidimensional de las bases de datos de gran volumen en las organizaciones, para realizar toma de decisiones de los mismos (que son el tema de consultas especiales. Un sistema OLAP debe cumplir las reglas del Dr. Codd: Se tiene que tener una visión multidimensional de los datos; Pensar en dimensiones y métricas de Negocio. No en tablas y en campos. Abstract This analytical process sets out the guidelines for the business world by carrying out a multidimensional analysis of high volume databases in organizations for decision-making. An OLAP system should obey the rules of Dr. Codd: you should have a multidimensional vision of the data: thinking in terms of the dimensions and metrics of business. Not tables and fields.

  19. Object-Extended OLAP Querying

    DEFF Research Database (Denmark)

    Pedersen, Torben Bach; Gu, Junmin; Shoshani, Arie

    2009-01-01

    On-line analytical processing (OLAP) systems based on a dimensional view of data have found widespread use in business applications and are being used increasingly in non-standard applications. These systems provide good performance and ease-of-use. However, the complex structures and relationshi...... with performance measurements that show that the approach is a viable alternative to a physically integrated data warehouse....

  20. View discovery in OLAP databases through statistical combinatorial optimization

    Energy Technology Data Exchange (ETDEWEB)

    Hengartner, Nick W [Los Alamos National Laboratory; Burke, John [PNNL; Critchlow, Terence [PNNL; Joslyn, Cliff [PNNL; Hogan, Emilie [PNNL

    2009-01-01

    OnLine Analytical Processing (OLAP) is a relational database technology providing users with rapid access to summary, aggregated views of a single large database, and is widely recognized for knowledge representation and discovery in high-dimensional relational databases. OLAP technologies provide intuitive and graphical access to the massively complex set of possible summary views available in large relational (SQL) structured data repositories. The capability of OLAP database software systems to handle data complexity comes at a high price for analysts, presenting them a combinatorially vast space of views of a relational database. We respond to the need to deploy technologies sufficient to allow users to guide themselves to areas of local structure by casting the space of 'views' of an OLAP database as a combinatorial object of all projections and subsets, and 'view discovery' as an search process over that lattice. We equip the view lattice with statistical information theoretical measures sufficient to support a combinatorial optimization process. We outline 'hop-chaining' as a particular view discovery algorithm over this object, wherein users are guided across a permutation of the dimensions by searching for successive two-dimensional views, pushing seen dimensions into an increasingly large background filter in a 'spiraling' search process. We illustrate this work in the context of data cubes recording summary statistics for radiation portal monitors at US ports.

  1. Sistem Pendukung Keputusan Penentuan Lokasi dan Pemetaan Secara Simultan dengan OLAP

    Directory of Open Access Journals (Sweden)

    Harindra W Pradhana

    2016-01-01

    Full Text Available This research proposes simultaneous localization and mapping (SLAM system processed separately from the robot using data ware house. Information in the data warehouse processed separately to allow complex computation held without lowering robotic system performance. The system helps making decision by analyzing information in the data warehouse. Decision support information visualized in vector graphics to helps robotic information interpretation. This system use online analytical processing (OLAP on processing and analyzing information in the data warehouse. Visualization process use SVG to display map from robotic data processing. Web server manages all of the processing and analysis of OLAP information and displays it through browser to the user. This research produces interactive and informative decision support system. The web server quickly process information and displays it to the browser. System processing and analysis generates relevant information with low error. For further research, conventional SLAM methods can be added to the server to operate the information in the data warehouse.

  2. WebGeoOlap: Multidimensional geographic data visualization for web environments

    Directory of Open Access Journals (Sweden)

    SILVA, R. O. L.

    2008-06-01

    Full Text Available As the web is continuously maturing platform, a growing number of technology is leading Geographic Information Systems (GIS and Analytical (OLAP closer to being developed for the web environment. The great challenge of this work is to integrate these technologies, OLAP and GIS, in a single application, using Ajax, so that the user can perform the analysis of analytical data and view data geographic in the map, using Google Maps.

  3. The M-OLAP Cube Selection Problem: A Hyper-polymorphic Algorithm Approach

    Science.gov (United States)

    Loureiro, Jorge; Belo, Orlando

    OLAP systems depend heavily on the materialization of multidimensional structures to speed-up queries, whose appropriate selection constitutes the cube selection problem. However, the recently proposed distribution of OLAP structures emerges to answer new globalization's requirements, capturing the known advantages of distributed databases. But this hardens the search for solutions, especially due to the inherent heterogeneity, imposing an extra characteristic of the algorithm that must be used: adaptability. Here the emerging concept known as hyper-heuristic can be a solution. In fact, having an algorithm where several (meta-)heuristics may be selected under the control of a heuristic has an intrinsic adaptive behavior. This paper presents a hyper-heuristic polymorphic algorithm used to solve the extended cube selection and allocation problem generated in M-OLAP architectures.

  4. Specifying OLAP Cubes On XML Data

    DEFF Research Database (Denmark)

    Jensen, Mikael Rune; Møller, Thomas Holmgren; Pedersen, Torben Bach

    in modern enterprises. In the data warehousing approach, selected information is extracted in advance and stored in a repository. This approach is used because of its high performance. However, in many situations a logical (rather than physical) integration of data is preferable. Previous web-based data......On-Line Analytical Processing (OLAP) enables analysts to gain insight into data through fast and interactive access to a variety of possible views on information, organized in a dimensional model. The demand for data integration is rapidly becoming larger as more and more information sources appear....... Extensible Markup Language (XML) is fast becoming the new standard for data representation and exchange on the World Wide Web. The rapid emergence of XML data on the web, e.g., business-to-business (B2B) ecommerce, is making it necessary for OLAP and other data analysis tools to handleXML data as well...

  5. Current data warehousing and OLAP technologies’ status applied to spatial databases

    Directory of Open Access Journals (Sweden)

    Diego Orlando Abril Fradel

    2007-01-01

    Full Text Available Organisations require their information on a timely, dynamic, friendly, centralised and easy-to-access basis for analysing it and taking correct decisions at the right time. Centralisation can be achieved with data warehouse technology. On-line analytical processing (OLAP is used for analysis. Technologies using graphics and maps in data presentation can be exploited for an overall view of a company and helping to take better decisions. Geo- graphic information systems (GIS are useful for spatially locating information and representing it using maps. Data warehouses are generally implemented with a multidimensional data model to make OLAP analysis easier. A fundamental point in this model is the definition of measurements and dimensions; geography lies within such dimensions. Many researchers have concluded that the geographic dimension is another attribute for describing data in current analysis systems but without having an in-depth study of its spatial feature and without locating them on a map, like GIS does. Seen this way, interoperability is necessary between GIS and OLAP (called spatial OLAP or SOLAP and several entities are currently researching this. This document summarises the current status of such research.

  6. Deteksi Outlier Transaksi Menggunakan Visualisasi-Olap Pada Data Warehouse Perguruan Tinggi Swasta

    Directory of Open Access Journals (Sweden)

    Gusti Ngurah Mega Nata

    2016-07-01

    Full Text Available Mendeteksi outlier pada data warehouse merupakan hal penting. Data pada data warehouse sudah diagregasi dan memiliki model multidimensional. Agregasi pada data warehouse dilakukan karena data warehouse digunakan untuk menganalisis data secara cepat pada top level manajemen. Sedangkan, model data multidimensional digunakan untuk melihat data dari berbagai dimensi objek bisnis. Jadi, Mendeteksi outlier pada data warehouse membutuhkan teknik yang dapat melihat outlier pada data yang sudah diagregasi dan dapat melihat dari berbagai dimensi objek bisnis. Mendeteksi outlier pada data warehouse akan menjadi tantangan baru.        Di lain hal, Visualisasi On-line Analytic process (OLAP merupakan tugas penting dalam menyajikan informasi trend (report pada data warehouse dalam bentuk visualisasi data. Pada penelitian ini, visualisasi OLAP digunakan untuk deteksi outlier transaksi. Maka, dalam penelitian ini melakukan analisis untuk mendeteksi outlier menggunakan visualisasi-OLAP. Operasi OLAP yang digunakan yaitu operasi drill-down. Jenis visualisasi yang akan digunakan yaitu visualisasi satu dimensi, dua dimensi dan multi dimensi menggunakan tool weave desktop. Pembangunan data warehouse dilakukan secara button-up. Studi kasus dilakukan pada perguruan tinggi swasta. Kasus yang diselesaikan yaitu mendeteksi outlier transaki pembayaran mahasiswa pada setiap semester. Deteksi outlier pada visualisasi data menggunakan satu tabel dimensional lebih mudah dianalisis dari pada deteksi outlier pada visualisasi data menggunakan dua atau multi tabel dimensional. Dengan kata lain semakin banyak tabel dimensi yang terlibat semakin sulit analisis deteksi outlier yang dilakukan. Kata kunci — Deteksi Outlier,  Visualisasi OLAP, Data warehouse

  7. Power Distribution Analysis For Electrical Usage In Province Area Using Olap (Online Analytical Processing

    Directory of Open Access Journals (Sweden)

    Samsinar Riza

    2018-01-01

    Full Text Available The distribution network is the closest power grid to the customer Electric service providers such as PT. PLN. The dispatching center of power grid companies is also the data center of the power grid where gathers great amount of operating information. The valuable information contained in these data means a lot for power grid operating management. The technique of data warehousing online analytical processing has been used to manage and analysis the great capacity of data. Specific methods for online analytics information systems resulting from data warehouse processing with OLAP are chart and query reporting. The information in the form of chart reporting consists of the load distribution chart based on the repetition of time, distribution chart on the area, the substation region chart and the electric load usage chart. The results of the OLAP process show the development of electric load distribution, as well as the analysis of information on the load of electric power consumption and become an alternative in presenting information related to peak load.

  8. Power Distribution Analysis For Electrical Usage In Province Area Using Olap (Online Analytical Processing)

    Science.gov (United States)

    Samsinar, Riza; Suseno, Jatmiko Endro; Widodo, Catur Edi

    2018-02-01

    The distribution network is the closest power grid to the customer Electric service providers such as PT. PLN. The dispatching center of power grid companies is also the data center of the power grid where gathers great amount of operating information. The valuable information contained in these data means a lot for power grid operating management. The technique of data warehousing online analytical processing has been used to manage and analysis the great capacity of data. Specific methods for online analytics information systems resulting from data warehouse processing with OLAP are chart and query reporting. The information in the form of chart reporting consists of the load distribution chart based on the repetition of time, distribution chart on the area, the substation region chart and the electric load usage chart. The results of the OLAP process show the development of electric load distribution, as well as the analysis of information on the load of electric power consumption and become an alternative in presenting information related to peak load.

  9. Efficient Approximate OLAP Querying Over Time Series

    DEFF Research Database (Denmark)

    Perera, Kasun Baruhupolage Don Kasun Sanjeewa; Hahmann, Martin; Lehner, Wolfgang

    2016-01-01

    The ongoing trend for data gathering not only produces larger volumes of data, but also increases the variety of recorded data types. Out of these, especially time series, e.g. various sensor readings, have attracted attention in the domains of business intelligence and decision making. As OLAP...... queries play a major role in these domains, it is desirable to also execute them on time series data. While this is not a problem on the conceptual level, it can become a bottleneck with regards to query run-time. In general, processing OLAP queries gets more computationally intensive as the volume...... of data grows. This is a particular problem when querying time series data, which generally contains multiple measures recorded at fine time granularities. Usually, this issue is addressed either by scaling up hardware or by employing workload based query optimization techniques. However, these solutions...

  10. Evaluation of SOVAT: an OLAP-GIS decision support system for community health assessment data analysis.

    Science.gov (United States)

    Scotch, Matthew; Parmanto, Bambang; Monaco, Valerie

    2008-06-09

    Data analysis in community health assessment (CHA) involves the collection, integration, and analysis of large numerical and spatial data sets in order to identify health priorities. Geographic Information Systems (GIS) enable for management and analysis using spatial data, but have limitations in performing analysis of numerical data because of its traditional database architecture.On-Line Analytical Processing (OLAP) is a multidimensional datawarehouse designed to facilitate querying of large numerical data. Coupling the spatial capabilities of GIS with the numerical analysis of OLAP, might enhance CHA data analysis. OLAP-GIS systems have been developed by university researchers and corporations, yet their potential for CHA data analysis is not well understood. To evaluate the potential of an OLAP-GIS decision support system for CHA problem solving, we compared OLAP-GIS to the standard information technology (IT) currently used by many public health professionals. SOVAT, an OLAP-GIS decision support system developed at the University of Pittsburgh, was compared against current IT for data analysis for CHA. For this study, current IT was considered the combined use of SPSS and GIS ("SPSS-GIS"). Graduate students, researchers, and faculty in the health sciences at the University of Pittsburgh were recruited. Each round consisted of: an instructional video of the system being evaluated, two practice tasks, five assessment tasks, and one post-study questionnaire. Objective and subjective measurement included: task completion time, success in answering the tasks, and system satisfaction. Thirteen individuals participated. Inferential statistics were analyzed using linear mixed model analysis. SOVAT was statistically significant (alpha = .01) from SPSS-GIS for satisfaction and time (p OLAP-GIS decision support systems as a valuable tool for CHA data analysis.

  11. Sistem Informasi Lulusan Dengan Metode Online Analitycal processing (OLAP Pada Politeknik Negeri Kupang

    Directory of Open Access Journals (Sweden)

    Lita Alfriany Ndoloe

    2014-02-01

    Full Text Available The  educational  institution  need  the  leadership/  decision  makers  are  always  trying  to  find  some  information  /  decisions  that  are beneficial to the students, so that when they graduate can get a job quickly. To make it easier to get the information using OLAP. The purpose  of this research  is  to  make  information  systems  graduates  by using  Online Analytical  Procesing  (OLAP.  In the  modelingsystem  used  Context  Diagram  and  Data  Flow  Diagram.  Information  systems  graduates  begins  with  collecting  data  on  graduates, perform  analysis  with  the  concept  of  Roll  Up,  presents  information  generated  OLAP  and  graphs.  Graduate  information  systemsprovide  information  quality  graduates,  useful  for leaders  to make decisions.  Graduate  information  systems  can be  applied to the State Polytechnic  Department of Electronics  Kupang.  Results  showed  developmental  process  OLAP  uptake  needs  graduates  in  public and private.Keywords: OLAP,Graduate  information systems, Roll Up

  12. IR and OLAP in XML document warehouses

    DEFF Research Database (Denmark)

    Perez, Juan Manuel; Pedersen, Torben Bach; Berlanga, Rafael

    2005-01-01

    In this paper we propose to combine IR and OLAP (On-Line Analytical Processing) technologies to exploit a warehouse of text-rich XML documents. In the system we plan to develop, a multidimensional implementation of a relevance modeling document model will be used for interactively querying...

  13. Using OLAP Data Cubes in Business Intelligence

    Directory of Open Access Journals (Sweden)

    Cristescu Marian Pompiliu

    2016-12-01

    Full Text Available The purpose of this paper is to demonstrate that it is possible to develop business intelligence projects in big and medium-size organizations, only with Microsoft products, used in accordance with standard OLAP cube technology, and presented possible alternatives, in relation with the requested functions.

  14. Evaluation of SOVAT: An OLAP-GIS decision support system for community health assessment data analysis

    Directory of Open Access Journals (Sweden)

    Parmanto Bambang

    2008-06-01

    Full Text Available Abstract Background Data analysis in community health assessment (CHA involves the collection, integration, and analysis of large numerical and spatial data sets in order to identify health priorities. Geographic Information Systems (GIS enable for management and analysis using spatial data, but have limitations in performing analysis of numerical data because of its traditional database architecture. On-Line Analytical Processing (OLAP is a multidimensional datawarehouse designed to facilitate querying of large numerical data. Coupling the spatial capabilities of GIS with the numerical analysis of OLAP, might enhance CHA data analysis. OLAP-GIS systems have been developed by university researchers and corporations, yet their potential for CHA data analysis is not well understood. To evaluate the potential of an OLAP-GIS decision support system for CHA problem solving, we compared OLAP-GIS to the standard information technology (IT currently used by many public health professionals. Methods SOVAT, an OLAP-GIS decision support system developed at the University of Pittsburgh, was compared against current IT for data analysis for CHA. For this study, current IT was considered the combined use of SPSS and GIS ("SPSS-GIS". Graduate students, researchers, and faculty in the health sciences at the University of Pittsburgh were recruited. Each round consisted of: an instructional video of the system being evaluated, two practice tasks, five assessment tasks, and one post-study questionnaire. Objective and subjective measurement included: task completion time, success in answering the tasks, and system satisfaction. Results Thirteen individuals participated. Inferential statistics were analyzed using linear mixed model analysis. SOVAT was statistically significant (α = .01 from SPSS-GIS for satisfaction and time (p Conclusion Using SOVAT, tasks were completed more efficiently, with a higher rate of success, and with greater satisfaction, than the

  15. Developing Access Control Model of Web OLAP over Trusted and Collaborative Data Warehouses

    Science.gov (United States)

    Fugkeaw, Somchart; Mitrpanont, Jarernsri L.; Manpanpanich, Piyawit; Juntapremjitt, Sekpon

    This paper proposes the design and development of Role- based Access Control (RBAC) model for the Single Sign-On (SSO) Web-OLAP query spanning over multiple data warehouses (DWs). The model is based on PKI Authentication and Privilege Management Infrastructure (PMI); it presents a binding model of RBAC authorization based on dimension privilege specified in attribute certificate (AC) and user identification. Particularly, the way of attribute mapping between DW user authentication and privilege of dimensional access is illustrated. In our approach, we apply the multi-agent system to automate flexible and effective management of user authentication, role delegation as well as system accountability. Finally, the paper culminates in the prototype system A-COLD (Access Control of web-OLAP over multiple DWs) that incorporates the OLAP features and authentication and authorization enforcement in the multi-user and multi-data warehouse environment.

  16. Enabling Spatial OLAP Over Environmental and Farming Data with QB4SOLAP

    DEFF Research Database (Denmark)

    Gur, Nurefsan; Hose, Katja; Pedersen, Torben Bach

    2016-01-01

    Governmental organizations and agencies have been making large amounts of spatial data available on the Semantic Web (SW). However, we still lack efficient techniques for analyzing such large amounts of data as we know them from relational database systems, e.g., multidimensional (MD) data...... warehouses and On-line Analytical Processing (OLAP). A basic prerequisite to enable such advanced analytics is a well-defined schema, which can be defined using the QB4SOLAP vocabulary that provides sufficient context for spatial OLAP (SOLAP). In this paper, we address the challenging problem of MD querying...

  17. High-Fidelity Aerothermal Engineering Analysis for Planetary Probes Using DOTNET Framework and OLAP Cubes Database

    Directory of Open Access Journals (Sweden)

    Prabhakar Subrahmanyam

    2009-01-01

    Full Text Available This publication presents the architecture integration and implementation of various modules in Sparta framework. Sparta is a trajectory engine that is hooked to an Online Analytical Processing (OLAP database for Multi-dimensional analysis capability. OLAP is an Online Analytical Processing database that has a comprehensive list of atmospheric entry probes and their vehicle dimensions, trajectory data, aero-thermal data and material properties like Carbon, Silicon and Carbon-Phenolic based Ablators. An approach is presented for dynamic TPS design. OLAP has the capability to run in one simulation several different trajectory conditions and the output is stored back into the database and can be queried for appropriate trajectory type. An OLAP simulation can be setup by spawning individual threads to run for three types of trajectory: Nominal, Undershoot and Overshoot trajectory. Sparta graphical user interface provides capabilities to choose from a list of flight vehicles or enter trajectory and geometry information of a vehicle in design. DOTNET framework acts as a middleware layer between the trajectory engine and the user interface and also between the web user interface and the OLAP database. Trajectory output can be obtained in TecPlot format, Excel output or in a KML (Keyhole Markup Language format. Framework employs an API (application programming interface to convert trajectory data into a formatted KML file that is used by Google Earth for simulating Earth-entry fly-by visualizations.

  18. PENGEMBANGAN DATA WAREHOUSE DAN ON-LINE ANALYTICAL PROCESSING (OLAP UNTUK PENEMUAN INFORMASI DAN ANALISIS DATA (Studi Kasus : Sistem Informasi Penerimaan Mahasiswa Baru STMIK AMIKOM PURWOKERTO

    Directory of Open Access Journals (Sweden)

    Giat Karyono

    2011-08-01

    Full Text Available Background preparation of this thesis report, Silva (2007 mentions that the competition for students between universities was inevitable as it grows, universities should equip themselves to survive in the competition that ultimately colleges that are not sensitive to compete. The demand for a high performance organization that has also faced by STMIK AMIKOM Purwokerto. Existing data on the colleges that are so big and much needed storage space allocation will be helped and be efficient with the data warehouse (Wikramanayake, 2006. Based on the data management / decision makers in education institutions is always a constant attempt to find an information / decision analysis that are useful in the search for new students. For the needs of the analysis method was used OLAP (OnLine Analytical Processing which presents the data in the form of multidimensional query that is easier to be presented and analyzed.Data collection methods used in the preparation of this report include the method of observation of interviews and field studies, literature, internet search, as well as observing systems that are already running.This research was conducted with the following steps: 1 The analysis system that includes the current SIPMB analysis, identification of the cause of the problem, analysis of system requirements. 2 System design, including design of data warehouses and OLAP applications PMB. This design produces data warehouse architecture, data modeling dimensional, the establishment of a data warehouse, OLAP stakeholders PMB, PMB OLAP viewpoint, scenario, model systems, and user interface design. 3 Implementation, covers the application of OLAP applications PMB and operations performed included, 4 testing system, test the product in accordance with ISO 9126 software includes six quality characteristics of Functionality, Reliability, Usability, efficiency, Maintainability, Portability. In order not to interfere the performance of the operational

  19. The Decoration Operator: A Foundation for On-Line Dimensional Data Integration

    DEFF Research Database (Denmark)

    Pedersen, Dennis; Pedersen, Torben Bach; Riis, Karsten

    2004-01-01

    The changing data requirements of today's dynamic business environments are not handled well by current On-Line Analytical Processing (OLAP) systems. Physically integrating unexpected, external data into OLAP cubes, i.e., the data warehousing approach, is a long and time-consuming process, making...... logical, on-the-fly, integration the better choice in many situations. However, OLAP systems have no operations for integrating existing multidimensional cube data with external data. In this paper we present a novel multidimensional algebra operator, the decoration operator, which allows external data...... to be integrated in OLAP cubes as new dimensions, i.e., the cube is ``decorated'' with new dimensions which can subsequently be used just as the regular dimensions. We formally specify the semantics of the decoration operator, ensuring that semantic problems do not occur in the data integration process. We also...

  20. Olap Cube Representation For Objectoriented Database

    OpenAIRE

    Vipin Saxena; Ajay Pratap

    2012-01-01

    In the current scenario, the size of database related to any organization is rapidly increasing and due to evolution of the object-oriented approach, many of the Software Industries are converting the old structured approach based softwares into the object-oriented based softwares. Therefore, for the largeamount of database, it is necessary to study the faster retrieval system as On-Line Analytical Processing (OLAP) which was introduced by E.Codd in 1993. The present paper is an attempt in t...

  1. Using online analytical processing to manage emergency department operations.

    Science.gov (United States)

    Gordon, Bradley D; Asplin, Brent R

    2004-11-01

    The emergency department (ED) is a unique setting in which to explore and evaluate the utility of information technology to improve health care operations. A potentially useful software tool in managing this complex environment is online analytical processing (OLAP). An OLAP system has the ability to provide managers, providers, and researchers with the necessary information to make decisions quickly and effectively by allowing them to examine patterns and trends in operations and patient flow. OLAP software quickly summarizes and processes data acquired from a variety of data sources, including computerized ED tracking systems. It allows the user to form a comprehensive picture of the ED from both system-wide and patient-specific perspectives and to interactively view the data using an approach that meets his or her needs. This article describes OLAP software tools and provides examples of potential OLAP applications for care improvement projects, primarily from the perspective of the ED. While OLAP is clearly a helpful tool in the ED, it is far more useful when integrated into the larger continuum of health information systems across a hospital or health care delivery system.

  2. The Implementation of Data Warehouse and OLAP for Rehabilitation Outcome Evaluation: ReDWinE System

    Science.gov (United States)

    Guo, Fei-Ran; Parmanto, Bambang; Irrgang, James J.; Wang, Jiunjie; Fang, Huaijin

    2000-01-01

    We created a data warehouse and OLAP system on the web for outcome evaluation of rehabilitation services. Thirteen outcome indicators were use in this research. Efficiency of therapists and clinics, expected utility of treatments and graphic patterns were generated for data exploration, data mining and decision support. Users can retrieve plenty of graphs and statistical tables without knowing database structure or attributes. Our experiences showed that multi-dimensional database and OLAP could serve as a decision support system.

  3. OLAP: A Fast, Easy, Affordable Executive Information System--Finally!

    Science.gov (United States)

    Stewart, Henry M.

    1995-01-01

    The University of Rochester's experience with online analytical processing (OLAP), part of its executive information system, is reported. The server, a multiuser, local area network (LAN)-based database loaded from legacy systems or a data warehouse, can rapidly manipulate and display data, and allows quick creation and changing of analytical…

  4. Web 2.0 OLAP: From Data Cubes to Tag Clouds

    Science.gov (United States)

    Aouiche, Kamel; Lemire, Daniel; Godin, Robert

    Increasingly, business projects are ephemeral. New Business Intelligence tools must support ad-lib data sources and quick perusal. Meanwhile, tag clouds are a popular community-driven visualization technique. Hence, we investigate tag-cloud views with support for OLAP operations such as roll-ups, slices, dices, clustering, and drill-downs. As a case study, we implemented an application where users can upload data and immediately navigate through its ad hoc dimensions. To support social networking, views can be easily shared and embedded in other Web sites. Algorithmically, our tag-cloud views are approximate range top-k queries over spontaneous data cubes. We present experimental evidence that iceberg cuboids provide adequate online approximations. We benchmark several browser-oblivious tag-cloud layout optimizations.

  5. Olap and data mining technologies' integration in the construction of interdimensional associative rules in multidimensional data

    Directory of Open Access Journals (Sweden)

    Микола Тихонович Фісун

    2015-06-01

    Full Text Available The features of associative rules in multidimensional data searching are presented in the article, specifically theoretical basis of association searching between different dimensions in OLAP cubes and formulas of their significance characteristics (support, confidence, lift, leverage calculation are shown. The method of interdimensional association rules generation is proposed. The implementation of this method as a component of operative and intellectual data analysis information system on database management system Caché platform is described.

  6. View Discovery in OLAP Databases through Statistical Combinatorial Optimization

    Energy Technology Data Exchange (ETDEWEB)

    Joslyn, Cliff A.; Burke, Edward J.; Critchlow, Terence J.

    2009-05-01

    The capability of OLAP database software systems to handle data complexity comes at a high price for analysts, presenting them a combinatorially vast space of views of a relational database. We respond to the need to deploy technologies sufficient to allow users to guide themselves to areas of local structure by casting the space of ``views'' of an OLAP database as a combinatorial object of all projections and subsets, and ``view discovery'' as an search process over that lattice. We equip the view lattice with statistical information theoretical measures sufficient to support a combinatorial optimization process. We outline ``hop-chaining'' as a particular view discovery algorithm over this object, wherein users are guided across a permutation of the dimensions by searching for successive two-dimensional views, pushing seen dimensions into an increasingly large background filter in a ``spiraling'' search process. We illustrate this work in the context of data cubes recording summary statistics for radiation portal monitors at US ports.

  7. OLAP-технологии

    OpenAIRE

    КАРЛОВА Е.А.; БАГАЕВА А.П.

    2013-01-01

    Рассмотрены виды аналитической обработки, преимущества информационно-аналитических систем на базе OLAP-анализа, итоги внедрения. Показано практическое применение OLAP-систем в Красноярском крае, а также для 1С.

  8. Development of an OLAP Based Fuzzy Logic System for Supporting Put Away Decision

    Directory of Open Access Journals (Sweden)

    S.H.Chung

    2009-10-01

    Full Text Available In today`s rapidly changing and globally volatile world, manufacturers pay strong efforts on conducting lean production, outsourcing their components, and management on the complex supply chain. Warehouse management plays a vital role to be a successful player in the any kinds of industry which put-away process is a key activity that brings significant influence and challenges to warehouse performance. In this dynamic operating environment, minimizing the operation mistakes and providing accurate real time inventory information to stakeholder become the basic requirements to be an order qualifier. An OLAP based intelligent system called Fuzzy Storage Assignment System (FSAS is proposed to increase availability of decision support data and convert the human knowledge into system for tackling the storage location assignment problem (SLAP. To validate the feasibility of this proposed system, a prototype will be worked out for a third party logistics company.

  9. Connecting traditional sciences with the OLAP and data mining paradigms

    Science.gov (United States)

    Guergachi, Aziz A.

    2003-03-01

    The paradigms of OLAP, multidimensional modeling and data mining have first emerged in the areas of market analysis and finance to address various needs of people working in these areas. Does this mean that they are useful and applicable in these areas only? Or, can they also be applicable in the other more traditional areas of science and engineering? What characterize the systems for which these paradigms are suitable? What are the goals of these paradigms? How do they relate to the traditional body of knowledge that has been developed throughout the centuries in the areas of mathematics, statistics, systems science and engineering? Where, how and to what extent can we leverage the conventional wisdom that has been accumulated in the aforementioned disciplines to develop a foundational basis for the above paradigms? The goal of this paper is to address these questions at the foundational level. We argue that the paradigms of OLAP, multidimensional modeling and data mining can also be applied successfully to complex engineering systems, such as membrane-based water/wastewater treatment plants, for example. We develop mathematically-based axiomatic definition of the concepts of 'dimension,' 'dimension level,' 'dimension hierarchy' and 'measure' using set theory and equivalence relations.

  10. Data Blocks: hybrid OLTP and OLAP on compressed storage using both vectorization and compilation

    NARCIS (Netherlands)

    H. Lang (Harald); T. Mühlbauer; F. Funke; P.A. Boncz (Peter); T. Neumann (Thomas); A. Kemper (Alfons)

    2016-01-01

    htmlabstractThis work aims at reducing the main-memory footprint in high performance hybrid OLTP & OLAP databases, while retaining high query performance and transactional throughput. For this purpose, an innovative compressed columnar storage format for cold data, called Data Blocks is introduced.

  11. Data Blocks : Hybrid OLTP and OLAP on compressed storage using both vectorization and compilation

    NARCIS (Netherlands)

    Lang, Harald; Mühlbauer, Tobias; Funke, Florian; Boncz, Peter; Neumann, Thomas; Kemper, Alfons

    2016-01-01

    This work aims at reducing the main-memory footprint in high performance hybrid OLTP&OLAP databases, while retaining high query performance and transactional throughput. For this purpose, an innovative compressed columnar storage format for cold data, called Data Blocks is introduced. Data Blocks

  12. Approximation des cubes OLAP et génération de règles dans les entrepôts de données

    Directory of Open Access Journals (Sweden)

    Sami Naouali

    2006-04-01

    Full Text Available This paper presents a new approach toward approximate query answering in data warehouses. The approach is based on an adaptation of rough set theory to multidimensional data, and offers cube exploration and mining facilities. The objective of this work is to integrate approximation mechanisms and associated operators into data cubes in order to produce views that can then be explored using OLAP or data mining techniques. The integration of data approximation capabilities with OLAP techniques offers additional facilities for cube exploration and analysis. The proposed approach allows the user to work either in a restricted mode using a cube lower approximation or in a relaxed mode using cube upper approximation. The former mode is useful when the query output is large, and hence allows the user to focus on a reduced set of fully matching tuples. The latter is useful when a query returns an empty or small answer set, and hence helps relax the query conditions so that a superset of the answer is returned.

  13. Fuzzy OLAP association rules mining-based modular reinforcement learning approach for multiagent systems.

    Science.gov (United States)

    Kaya, Mehmet; Alhajj, Reda

    2005-04-01

    Multiagent systems and data mining have recently attracted considerable attention in the field of computing. Reinforcement learning is the most commonly used learning process for multiagent systems. However, it still has some drawbacks, including modeling other learning agents present in the domain as part of the state of the environment, and some states are experienced much less than others, or some state-action pairs are never visited during the learning phase. Further, before completing the learning process, an agent cannot exhibit a certain behavior in some states that may be experienced sufficiently. In this study, we propose a novel multiagent learning approach to handle these problems. Our approach is based on utilizing the mining process for modular cooperative learning systems. It incorporates fuzziness and online analytical processing (OLAP) based mining to effectively process the information reported by agents. First, we describe a fuzzy data cube OLAP architecture which facilitates effective storage and processing of the state information reported by agents. This way, the action of the other agent, not even in the visual environment. of the agent under consideration, can simply be predicted by extracting online association rules, a well-known data mining technique, from the constructed data cube. Second, we present a new action selection model, which is also based on association rules mining. Finally, we generalize not sufficiently experienced states, by mining multilevel association rules from the proposed fuzzy data cube. Experimental results obtained on two different versions of a well-known pursuit domain show the robustness and effectiveness of the proposed fuzzy OLAP mining based modular learning approach. Finally, we tested the scalability of the approach presented in this paper and compared it with our previous work on modular-fuzzy Q-learning and ordinary Q-learning.

  14. A spatio-temporal extension to the map cube operator

    Science.gov (United States)

    Alzate, Juan C.; Moreno, Francisco J.; Echeverri, Jaime

    2012-09-01

    OLAP (On Line Analytical Processing) is a set of techniques and operators to facilitate the data analysis usually stored in a data warehouse. In this paper, we extend the functionality of an OLAP operator known as Map Cube with the definition and incorporation of a function that allows the formulation of spatio-temporal queries. For example, consider a data warehouse about crimes that includes data about the places where the crimes were committed. Suppose we want to find and visualize the trajectory (a trajectory is just the path that an object follows through space as a function of time) of the crimes of a suspect beginning with his oldest crime and ending with his most recent one. In order to meet this requirement, we extend the Map Cube operator.

  15. Algorithms for synthesizing management solutions based on OLAP-technologies

    Science.gov (United States)

    Pishchukhin, A. M.; Akhmedyanova, G. F.

    2018-05-01

    OLAP technologies are a convenient means of analyzing large amounts of information. An attempt was made in their work to improve the synthesis of optimal management decisions. The developed algorithms allow forecasting the needs and accepted management decisions on the main types of the enterprise resources. Their advantage is the efficiency, based on the simplicity of quadratic functions and differential equations of only the first order. At the same time, the optimal redistribution of resources between different types of products from the assortment of the enterprise is carried out, and the optimal allocation of allocated resources in time. The proposed solutions can be placed on additional specially entered coordinates of the hypercube representing the data warehouse.

  16. Modelling Financial-Accounting Decisions by Means of OLAP Tools

    Directory of Open Access Journals (Sweden)

    Diana Elena CODREAN

    2011-03-01

    Full Text Available At present, one can say that a company’s good running largely depends on the information quantity and quality it relies on when making decisions. The information needed to underlie decisions and be obtained due to the existence of a high-performing information system which makes it possible for the data to be shown quickly, synthetically and truly, also providing the opportunity for complex analyses and predictions. In such circumstances, computerized accounting systems, too, have grown their complexity by means of data analyzing information solutions such as OLAP and Data Mining which help perform a multidimensional analysis of financial-accounting data, potential frauds can be detected and data hidden information can be revealed, trends for certain indicators can be set up, therefore ensuring useful information to a company’s decision making.

  17. Considerations about using OLAP Cubes and Self-Service BI Tools for BI Systems’ Development

    Directory of Open Access Journals (Sweden)

    Gianina MIHAI

    2017-12-01

    Full Text Available Nowadays, the decision-making process must be an extremely fast one. This is why any decision-maker in a company must obtain information from the multiple available data source used in its transactional systems as easily and as quickly as possible. Business Intelligence (BI systems are the ones that provide the tools necessary for obtaining this information. In this article, we shall present the strengths and weaknesses regarding data analyses in a BI system using OLAP cubes and self-service BI tools.

  18. On-Line Analytical Processing (OLAP as a Information Tool for Modern Management

    Directory of Open Access Journals (Sweden)

    Hanna Borzęcka

    2007-12-01

    Full Text Available The article contains on question, what it is the wholesalers of data and what are the advantage from its initiating. It defines the actual information needs for management as well as it defines the part of wholesalers of data in satisfying these needs. It the conception of multidimensional structures of data, in the article formalize multidimensional model of data and basic structure wholesalers data are introduced, built according to authoressí own conception. It is the OLAP cube. Publication contains also the proposal of innovation and it forecasts the rise of new generation of wholesalers data for solving modern management problems.

  19. Easier surveillance of climate-related health vulnerabilities through a Web-based spatial OLAP application

    Directory of Open Access Journals (Sweden)

    Gosselin Pierre

    2009-04-01

    Full Text Available Abstract Background Climate change has a significant impact on population health. Population vulnerabilities depend on several determinants of different types, including biological, psychological, environmental, social and economic ones. Surveillance of climate-related health vulnerabilities must take into account these different factors, their interdependence, as well as their inherent spatial and temporal aspects on several scales, for informed analyses. Currently used technology includes commercial off-the-shelf Geographic Information Systems (GIS and Database Management Systems with spatial extensions. It has been widely recognized that such OLTP (On-Line Transaction Processing systems were not designed to support complex, multi-temporal and multi-scale analysis as required above. On-Line Analytical Processing (OLAP is central to the field known as BI (Business Intelligence, a key field for such decision-support systems. In the last few years, we have seen a few projects that combine OLAP and GIS to improve spatio-temporal analysis and geographic knowledge discovery. This has given rise to SOLAP (Spatial OLAP and a new research area. This paper presents how SOLAP and climate-related health vulnerability data were investigated and combined to facilitate surveillance. Results Based on recent spatial decision-support technologies, this paper presents a spatio-temporal web-based application that goes beyond GIS applications with regard to speed, ease of use, and interactive analysis capabilities. It supports the multi-scale exploration and analysis of integrated socio-economic, health and environmental geospatial data over several periods. This project was meant to validate the potential of recent technologies to contribute to a better understanding of the interactions between public health and climate change, and to facilitate future decision-making by public health agencies and municipalities in Canada and elsewhere. The project also aimed at

  20. Easier surveillance of climate-related health vulnerabilities through a Web-based spatial OLAP application.

    Science.gov (United States)

    Bernier, Eveline; Gosselin, Pierre; Badard, Thierry; Bédard, Yvan

    2009-04-03

    Climate change has a significant impact on population health. Population vulnerabilities depend on several determinants of different types, including biological, psychological, environmental, social and economic ones. Surveillance of climate-related health vulnerabilities must take into account these different factors, their interdependence, as well as their inherent spatial and temporal aspects on several scales, for informed analyses. Currently used technology includes commercial off-the-shelf Geographic Information Systems (GIS) and Database Management Systems with spatial extensions. It has been widely recognized that such OLTP (On-Line Transaction Processing) systems were not designed to support complex, multi-temporal and multi-scale analysis as required above. On-Line Analytical Processing (OLAP) is central to the field known as BI (Business Intelligence), a key field for such decision-support systems. In the last few years, we have seen a few projects that combine OLAP and GIS to improve spatio-temporal analysis and geographic knowledge discovery. This has given rise to SOLAP (Spatial OLAP) and a new research area. This paper presents how SOLAP and climate-related health vulnerability data were investigated and combined to facilitate surveillance. Based on recent spatial decision-support technologies, this paper presents a spatio-temporal web-based application that goes beyond GIS applications with regard to speed, ease of use, and interactive analysis capabilities. It supports the multi-scale exploration and analysis of integrated socio-economic, health and environmental geospatial data over several periods. This project was meant to validate the potential of recent technologies to contribute to a better understanding of the interactions between public health and climate change, and to facilitate future decision-making by public health agencies and municipalities in Canada and elsewhere. The project also aimed at integrating an initial collection of geo

  1. Application of SIG and OLAP technologies on IBGE databases as a decision support tool for the county administration

    Directory of Open Access Journals (Sweden)

    REGO, E. A.

    2008-06-01

    Full Text Available This paper shows a Decision Support System development for any brazilian county. The system is free of any costs research. For doing so, one uses the datawarehouse, OLAP and GIS technologies all together with the IBGE's database to give to the user a query building tool, showing the results in maps or/and tables format, on a very simple and efficient way.

  2. Generación de escenarios de planificación de redes mediante técnicas OLAP

    OpenAIRE

    Ramos García, Jesús

    2015-01-01

    RESUMEN: Debido a la gran cantidad de datos que a veces se tienen que manejar, es necesario el uso de herramientas que se encarguen de almacenar, reducir, extraer, analizar, procesar o modificar dichos datos de la forma más rápida y sencilla posible. Las bases de datos multidimensionales, con el nombre de cubo OLAP (On-Line Analytical Processing) se encargan de representar la información elegida de forma multidimensional, es decir, mediante cubos de varias dimensiones, haciendo que dicha info...

  3. A Framework for Developing Real-Time OLAP algorithm using Multi-core processing and GPU: Heterogeneous Computing

    International Nuclear Information System (INIS)

    Alzeini, H I; Hameed, Sh A; Habaebi, M H

    2013-01-01

    The overwhelmingly increasing amount of stored data has spurred researchers seeking different methods in order to optimally take advantage of it which mostly have faced a response time problem as a result of this enormous size of data. Most of solutions have suggested materialization as a favourite solution. However, such a solution cannot attain Real-Time answers anyhow. In this paper we propose a framework illustrating the barriers and suggested solutions in the way of achieving Real-Time OLAP answers that are significantly used in decision support systems and data warehouses

  4. A Framework for Developing Real-Time OLAP algorithm using Multi-core processing and GPU: Heterogeneous Computing

    Science.gov (United States)

    Alzeini, H. I.; Hameed, Sh A.; Habaebi, M. H.

    2013-12-01

    The overwhelmingly increasing amount of stored data has spurred researchers seeking different methods in order to optimally take advantage of it which mostly have faced a response time problem as a result of this enormous size of data. Most of solutions have suggested materialization as a favourite solution. However, such a solution cannot attain Real-Time answers anyhow. In this paper we propose a framework illustrating the barriers and suggested solutions in the way of achieving Real-Time OLAP answers that are significantly used in decision support systems and data warehouses.

  5. ANALISA PEMROSESAN DATA SECARA ONLINE ( ONLINE ANALYTICAL PROCESSING / OLAP UNTUK DUNIA PENDIDIKAN

    Directory of Open Access Journals (Sweden)

    Budi Santosa

    2015-04-01

    Full Text Available The development of database technology is currently very rapidly , many forms have only used as data storage technology that consists of fields , and the record is processed and displayed a variety of display formats of information in a simple , but now stems from the simple form have obtained a method for displaying a database useful to analyze the data for a particular purpose . By utilizing existing relational database then obtained a way to anticipate the need to analyze data quickly to help get a decision in an organization Methodology that will be used in this study include ; Literature and SDLC ( System Development Life Cycle which includes the step of Analysis , Design , Implementation , Testing and Maintenance . Software used to build this application is SQL Server 2012 . The results of this study are business intelligence applications with OLAP concepts for education ( case study in Informatics Engineering Department UPN " Veteran " Yogyakarta that can help to get information quickly and accurately in analyzing student data and analysis that analyzes ipk credits .

  6. Regular Expression Matching and Operational Semantics

    Directory of Open Access Journals (Sweden)

    Asiri Rathnayake

    2011-08-01

    Full Text Available Many programming languages and tools, ranging from grep to the Java String library, contain regular expression matchers. Rather than first translating a regular expression into a deterministic finite automaton, such implementations typically match the regular expression on the fly. Thus they can be seen as virtual machines interpreting the regular expression much as if it were a program with some non-deterministic constructs such as the Kleene star. We formalize this implementation technique for regular expression matching using operational semantics. Specifically, we derive a series of abstract machines, moving from the abstract definition of matching to increasingly realistic machines. First a continuation is added to the operational semantics to describe what remains to be matched after the current expression. Next, we represent the expression as a data structure using pointers, which enables redundant searches to be eliminated via testing for pointer equality. From there, we arrive both at Thompson's lockstep construction and a machine that performs some operations in parallel, suitable for implementation on a large number of cores, such as a GPU. We formalize the parallel machine using process algebra and report some preliminary experiments with an implementation on a graphics processor using CUDA.

  7. Uma análise comparativa de funções MDX nos servidores Analysis Services e Mondrian

    OpenAIRE

    ALBUQUERQUE, Erivam Anselmo de

    2013-01-01

    A MultiDimensional eXpression (MDX) é uma linguagem de consulta para processamento analítico de dados ou On-line Analytical Processing (OLAP). Apesar de esta linguagem ser usada pela maioria dos servidores OLAP, esta não é um padrão de direito. Portanto, tem-se pouca (ou nenhuma) garantia de que as funções MDX usadas por um servidor OLAP também possam ser usadas em outros servidores. Neste contexto, de forma a comparar as funções MDX de um servidor OLAP de código aberto e outro de código fech...

  8. Using data mining and OLAP to discover patterns in a database of patients with Y-chromosome deletions.

    Science.gov (United States)

    Dzeroski, S; Hristovski, D; Peterlin, B

    2000-01-01

    The paper presents a database of published Y chromosome deletions and the results of analyzing the database with data mining techniques. The database describes 382 patients for which 177 different markers were tested: 364 of the 382 patients had deletions. Two data mining techniques, clustering and decision tree induction were used. Clustering was used to group patients according to the overall presence/absence of deletions at the tested markers. Decision trees and On-Line-Analytical-Processing (OLAP) were used to inspect the resulting clustering and look for correlations between deletion patterns, populations and the clinical picture of infertility. The results of the analysis indicate that there are correlations between deletion patterns and patient populations, as well as clinical phenotype severity.

  9. A Query Cache Tool for Optimizing Repeatable and Parallel OLAP Queries

    Science.gov (United States)

    Santos, Ricardo Jorge; Bernardino, Jorge

    On-line analytical processing against data warehouse databases is a common form of getting decision making information for almost every business field. Decision support information oftenly concerns periodic values based on regular attributes, such as sales amounts, percentages, most transactioned items, etc. This means that many similar OLAP instructions are periodically repeated, and simultaneously, between the several decision makers. Our Query Cache Tool takes advantage of previously executed queries, storing their results and the current state of the data which was accessed. Future queries only need to execute against the new data, inserted since the queries were last executed, and join these results with the previous ones. This makes query execution much faster, because we only need to process the most recent data. Our tool also minimizes the execution time and resource consumption for similar queries simultaneously executed by different users, putting the most recent ones on hold until the first finish and returns the results for all of them. The stored query results are held until they are considered outdated, then automatically erased. We present an experimental evaluation of our tool using a data warehouse based on a real-world business dataset and use a set of typical decision support queries to discuss the results, showing a very high gain in query execution time.

  10. Hydro-meteorological data analysis using OLAP techniques

    Directory of Open Access Journals (Sweden)

    Néstor Darío Duque-Méndez

    2014-01-01

    Full Text Available La riqueza de los datos registrados por las redes de estaciones hidrometeorológicas ofrece una gran oportunidad para analizar, conocer y entender mejor las variables hidroclimatológicas. Por lo tanto, el almacenamiento eficiente de los datos y su tratamiento eficaz son un requisito previo para la investigación meteorológica e hidrológica que requiere de estrategias para que la captación, transmisión, almacenamiento y procesamiento de datos que garanticen su calidad y consistencia. El propósito de este trabajo es desarrollar un modelo conceptual para una bodega de datos diseñada en un esquema en estrella que permita el almacenamiento estructurado y el análisis multidimensional de series históricas de datos hidroclimatológicos. La información registrada por las redes telemétricas de estaciones hidrometeorológicas existentes en Manizales y en el Departamento de Caldas son la fuente de información. El esquema de bodega de datos propuesto aprovecha los datos disponibles (en algunos casos más de 50 años con el fin de aplicar procesamiento analítico en línea (OLAP para analizar la calidad de la información y descubrir relaciones ocultas entre las variables, en una región particularmente afectada por el cambio climático y especialmente por fenómenos de variabilidad climática. La principal contribución de este documento abarca la exploración de alternativas a los métodos tradicionales de almacenamiento y análisis de información y la presentación de un número de casos que demuestran la eficacia del modelo propuesto en la evaluación de la calidad de los datos y de la visualización de las relaciones entre las diversas variables a diferentes escalas y para casos específicos.

  11. Intelligent Data Analysis in the EMERCOM Information System

    Science.gov (United States)

    Elena, Sharafutdinova; Tatiana, Avdeenko; Bakaev, Maxim

    2017-01-01

    The paper describes an information system development project for the Russian Ministry of Emergency Situations (MES, whose international operations body is known as EMERCOM), which was attended by the representatives of both the IT industry and the academia. Besides the general description of the system, we put forward OLAP and Data Mining-based approaches towards the intelligent analysis of the data accumulated in the database. In particular, some operational OLAP reports and an example of multi-dimensional information space based on OLAP Data Warehouse are presented. Finally, we outline Data Mining application to support decision-making regarding security inspections planning and results consideration.

  12. Применение OLAP-технологий и OLAP-систем в экономической сфере

    OpenAIRE

    ГЕРШЕВИЧ Е.К.; ДОЛГОВА Т.Г.

    2012-01-01

    Задача принятия эффективных решений на всех уровнях управления организацией (производственных, маркетинговых, и кадровых решений; решений, затрагивающих цены, скидки), которые в конечном итоге приведут к успеху всей организации в целом, может быть реализована с помощью применения OLAP-технологий и OLAP-систем....

  13. Analisis Data Penjualan Perusahaan Detergen XYZ dengan Aplikasi Zoho Reporting Menggunakan Metode OLAP (Online Analytycal Processing

    Directory of Open Access Journals (Sweden)

    Ricky Akbar

    2017-06-01

    Full Text Available Sales Channel atau saluran penjualan merupakan salah satu hal yang harus diperhatikan oleh perusahaan. Sales channel yang beragam memungkin perusahaan untuk memperbesar keuntungan mereka, sales channel online misalnya dengan sales channel ini perusahaan dapat memperluas lokasi pemasaran keseluruh negara-negara di dunia. Perusahaan yang memiliki sales channel yang banyak dan memproduksi barang yang biasa digunakan sehari-hari, memiliki data pelanggan yang sangat besar diberbagai belahan dunia. Prediksi jumlah penjualan produk di masing-masing negara berdasarkan sales channel yang digunkan perusahaan merupakan Business Intelligence (BI yang sangat penting untuk melihat negara mana yang berpotensi memberikan pelanggan yang besar untuk penjualan produk perusahaan. Dari penelitian dengan menggunakan metode OLAP (Online Analytical Processing dan aplikasi Zoho Reporting, dapat membantu pihak pengambil keputusan dalam menemukan pelanggan dari negara mana yang nantinya berpotensi memberikan keuntungan besar bagi perusahaan. Kata kunci— business intelligence, online analytical processing, sales channel, prediksi.

  14. Optical linear algebra processors - Noise and error-source modeling

    Science.gov (United States)

    Casasent, D.; Ghosh, A.

    1985-01-01

    The modeling of system and component noise and error sources in optical linear algebra processors (OLAPs) are considered, with attention to the frequency-multiplexed OLAP. General expressions are obtained for the output produced as a function of various component errors and noise. A digital simulator for this model is discussed.

  15. Optical linear algebra processors: noise and error-source modeling.

    Science.gov (United States)

    Casasent, D; Ghosh, A

    1985-06-01

    The modeling of system and component noise and error sources in optical linear algebra processors (OLAP's) are considered, with attention to the frequency-multiplexed OLAP. General expressions are obtained for the output produced as a function of various component errors and noise. A digital simulator for this model is discussed.

  16. Determining Community Health Status Priorities in an Online Analytic Processing (OLAP) Environment

    Science.gov (United States)

    Studnicki, James; Fisher, John W.

    2013-01-01

    Introduction: The determination of priorities is an essential component of community health status assessment. Yet, there is an acknowledged need for a systematic method which will utilize data in standardized comparisons to yield priorities based on objective analyses. Method: We have deployed a web-based system with: a flexible online analytic processing (OLAP) interface; multiple sources of event-level data conformed to common definitions in a data warehouse structure; and, centralized technical infrastructure with distributed analytical capabilities. The PRIORITIZATION TOOL integrated into the system takes full advantage of the granularity of multidimensional sources of data to: apply a series of defined objective criteria; vary the weight of those criteria and detect the reordering of the rankings in real-time; and, apply the prioritization algorithm to different categories of health status outcomes. Results: In our example, mortality outcomes for Miami-Dade County, Florida, were considered with three different weighting combinations of the four primary ranking criteria. The resultant analyses return markedly different mortality priority rankings based upon the selection and weighting of the criteria. Conclusion: Rankings of community health outcomes based on a static set of criteria with fixed weighting factors may not provide sufficient information necessary for priority setting and may, in fact, be misleading. PMID:23923094

  17. Determining Community Health Status Priorities in an Online Analytic Processing (OLAP) Environment.

    Science.gov (United States)

    Studnicki, James; Fisher, John W

    2013-01-01

    The determination of priorities is an essential component of community health status assessment. Yet, there is an acknowledged need for a systematic method which will utilize data in standardized comparisons to yield priorities based on objective analyses. We have deployed a web-based system with: a flexible online analytic processing (OLAP) interface; multiple sources of event-level data conformed to common definitions in a data warehouse structure; and, centralized technical infrastructure with distributed analytical capabilities. The PRIORITIZATION TOOL integrated into the system takes full advantage of the granularity of multidimensional sources of data to: apply a series of defined objective criteria; vary the weight of those criteria and detect the reordering of the rankings in real-time; and, apply the prioritization algorithm to different categories of health status outcomes. In our example, mortality outcomes for Miami-Dade County, Florida, were considered with three different weighting combinations of the four primary ranking criteria. The resultant analyses return markedly different mortality priority rankings based upon the selection and weighting of the criteria. Rankings of community health outcomes based on a static set of criteria with fixed weighting factors may not provide sufficient information necessary for priority setting and may, in fact, be misleading.

  18. Useless brackets in arithmetic expressions with mixed operations

    OpenAIRE

    Gunnarsson, Robert; Hernell, Bernt; Sönnerhed, Wang Wei

    2012-01-01

    There can be different intentions with brackets in mathematical expressions. It has previously been suggested that mathematically useless brackets can be educationally useful when learning the order of operations in expressions with mixed operations. This paper reports how students (12-13 years) deal with the implicit mental conflict between brackets as a necessary part of the order of operations and brackets to emphasize precedence. The students taking part in this quasi-experimental study w...

  19. Automatic Facial Expression Recognition and Operator Functional State

    Science.gov (United States)

    Blanson, Nina

    2012-01-01

    The prevalence of human error in safety-critical occupations remains a major challenge to mission success despite increasing automation in control processes. Although various methods have been proposed to prevent incidences of human error, none of these have been developed to employ the detection and regulation of Operator Functional State (OFS), or the optimal condition of the operator while performing a task, in work environments due to drawbacks such as obtrusiveness and impracticality. A video-based system with the ability to infer an individual's emotional state from facial feature patterning mitigates some of the problems associated with other methods of detecting OFS, like obtrusiveness and impracticality in integration with the mission environment. This paper explores the utility of facial expression recognition as a technology for inferring OFS by first expounding on the intricacies of OFS and the scientific background behind emotion and its relationship with an individual's state. Then, descriptions of the feedback loop and the emotion protocols proposed for the facial recognition program are explained. A basic version of the facial expression recognition program uses Haar classifiers and OpenCV libraries to automatically locate key facial landmarks during a live video stream. Various methods of creating facial expression recognition software are reviewed to guide future extensions of the program. The paper concludes with an examination of the steps necessary in the research of emotion and recommendations for the creation of an automatic facial expression recognition program for use in real-time, safety-critical missions

  20. Automatic Facial Expression Recognition and Operator Functional State

    Science.gov (United States)

    Blanson, Nina

    2011-01-01

    The prevalence of human error in safety-critical occupations remains a major challenge to mission success despite increasing automation in control processes. Although various methods have been proposed to prevent incidences of human error, none of these have been developed to employ the detection and regulation of Operator Functional State (OFS), or the optimal condition of the operator while performing a task, in work environments due to drawbacks such as obtrusiveness and impracticality. A video-based system with the ability to infer an individual's emotional state from facial feature patterning mitigates some of the problems associated with other methods of detecting OFS, like obtrusiveness and impracticality in integration with the mission environment. This paper explores the utility of facial expression recognition as a technology for inferring OFS by first expounding on the intricacies of OFS and the scientific background behind emotion and its relationship with an individual's state. Then, descriptions of the feedback loop and the emotion protocols proposed for the facial recognition program are explained. A basic version of the facial expression recognition program uses Haar classifiers and OpenCV libraries to automatically locate key facial landmarks during a live video stream. Various methods of creating facial expression recognition software are reviewed to guide future extensions of the program. The paper concludes with an examination of the steps necessary in the research of emotion and recommendations for the creation of an automatic facial expression recognition program for use in real-time, safety-critical missions.

  1. Classification of user interfaces for graph-based online analytical processing

    Science.gov (United States)

    Michaelis, James R.

    2016-05-01

    In the domain of business intelligence, user-oriented software for conducting multidimensional analysis via Online- Analytical Processing (OLAP) is now commonplace. In this setting, datasets commonly have well-defined sets of dimensions and measures around which analysis tasks can be conducted. However, many forms of data used in intelligence operations - deriving from social networks, online communications, and text corpora - will consist of graphs with varying forms of potential dimensional structure. Hence, enabling OLAP over such data collections requires explicit definition and extraction of supporting dimensions and measures. Further, as Graph OLAP remains an emerging technique, limited research has been done on its user interface requirements. Namely, on effective pairing of interface designs to different types of graph-derived dimensions and measures. This paper presents a novel technique for pairing of user interface designs to Graph OLAP datasets, rooted in Analytic Hierarchy Process (AHP) driven comparisons. Attributes of the classification strategy are encoded through an AHP ontology, developed in our alternate work and extended to support pairwise comparison of interfaces. Specifically, according to their ability, as perceived by Subject Matter Experts, to support dimensions and measures corresponding to Graph OLAP dataset attributes. To frame this discussion, a survey is provided both on existing variations of Graph OLAP, as well as existing interface designs previously applied in multidimensional analysis settings. Following this, a review of our AHP ontology is provided, along with a listing of corresponding dataset and interface attributes applicable toward SME recommendation structuring. A walkthrough of AHP-based recommendation encoding via the ontology-based approach is then provided. The paper concludes with a short summary of proposed future directions seen as essential for this research area.

  2. SM4MQ: A Semantic Model for Multidimensional Queries

    DEFF Research Database (Denmark)

    Varga, Jovan; Dobrokhotova, Ekaterina; Romero, Oscar

    2017-01-01

    On-Line Analytical Processing (OLAP) is a data analysis approach to support decision-making. On top of that, Exploratory OLAP is a novel initiative for the convergence of OLAP and the Semantic Web (SW) that enables the use of OLAP techniques on SW data. Moreover, OLAP approaches exploit different......, sharing, and reuse on the SW. As OLAP is based on the underlying multidimensional (MD) data model we denote such queries as MD queries and define SM4MQ: A Semantic Model for Multidimensional Queries. Furthermore, we propose a method to automate the exploitation of queries by means of SPARQL. We apply...

  3. A Conceptual Model for Multidimensional Analysis of Documents

    Science.gov (United States)

    Ravat, Franck; Teste, Olivier; Tournier, Ronan; Zurlfluh, Gilles

    Data warehousing and OLAP are mainly used for the analysis of transactional data. Nowadays, with the evolution of Internet, and the development of semi-structured data exchange format (such as XML), it is possible to consider entire fragments of data such as documents as analysis sources. As a consequence, an adapted multidimensional analysis framework needs to be provided. In this paper, we introduce an OLAP multidimensional conceptual model without facts. This model is based on the unique concept of dimensions and is adapted for multidimensional document analysis. We also provide a set of manipulation operations.

  4. Hepatobiliary transporter expression and post-operative jaundice in patients undergoing partial hepatectomy.

    Science.gov (United States)

    Bernhardt, Gerwin A; Zollner, Gernot; Cerwenka, Herwig; Kornprat, Peter; Fickert, Peter; Bacher, Heinz; Werkgartner, Georg; Müller, Gabriele; Zatloukal, Kurt; Mischinger, Hans-Jörg; Trauner, Michael

    2012-01-01

    Post-operative hyperbilirubinaemia in patients undergoing liver resections is associated with high morbidity and mortality. Apart from different known factors responsible for the development of post-operative jaundice, little is known about the role of hepatobiliary transport systems in the pathogenesis of post-operative jaundice in humans after liver resection. Two liver tissue samples were taken from 14 patients undergoing liver resection before and after Pringle manoeuvre. Patients were retrospectively divided into two groups according to post-operative bilirubin serum levels. The two groups were analysed comparing the results of hepatobiliary transporter [Na-taurocholate cotransporter (NTCP); multidrug resistance gene/phospholipid export pump(MDR3); bile salt export pump (BSEP); canalicular bile salt export pump (MRP2)], heat shock protein 70 (HSP70) expression as well as the results of routinely taken post-operative liver chemistry tests. Patients with low post-operative bilirubin had lower levels of NTCP, MDR3 and BSEP mRNA compared to those with high bilirubin after Pringle manoeuvre. HSP70 levels were significantly higher after ischaemia-reperfusion (IR) injury in both groups resulting in 4.5-fold median increase. Baseline median mRNA expression of all four transporters prior to Pringle manoeuvre tended to be lower in the low bilirubin group whereas expression of HSP70 was higher in the low bilirubin group compared to the high bilirubin group. Higher mRNA levels of HSP70 in the low bilirubin group could indicate a possible protective effect of high HSP70 levels against IR injury. Although the exact role of hepatobiliary transport systems in the development of post-operative hyper bilirubinemia is not yet completely understood, this study provides new insights into the molecular aspects of post-operative jaundice after liver surgery. © 2011 John Wiley & Sons A/S.

  5. Determination of Anger Expression and Anger Management Styles and an Application on Operating Room Nurses

    Directory of Open Access Journals (Sweden)

    Hülya Aslan

    2016-12-01

    Full Text Available This research has been carried out in order to determine anger expression and anger management styles in operating room nurses. By applying an in-depth interview technique on operating room nurses working in a private hospital, a qualitative study has been performed in order to determine anger expression and anger management styles in operating room nurses. The interview consisted of ten questions such as demographic questions addressing the workers’ age, sex, education level and duration of employment in the organization they work, aiming to determine their anger expression and anger management styles. Since operating room environments contain various risk factors, and require active team work in a stressful dynamic setting under excessive workload, , it has been found that operating room nurses display their anger through loud speaking, fail to settle their anger positively, fail to control their anger in a behavioural pattern despite their cognitive awareness in anger management. Thus, it has been suggested that operating room nurses should be trained on anger management methods so that they can manage their anger in a stressful operating room environment.

  6. Closed-form expressions for time-frequency operations involving Hermite functions

    NARCIS (Netherlands)

    Korevaar, C.W.; Oude Alink, M.S.; de Boer, Pieter-Tjerk; Kokkeler, Andre B.J.; Smit, Gerardus Johannes Maria

    2016-01-01

    The product, convolution, correlation, Wigner distribution function (WDF) and ambiguity function (AF) of two Hermite functions of arbitrary order n and m are derived and expressed as a bounded, weighted sum of n+m Hermite functions. It was already known that these mathematical operations performed

  7. Prognostic risk estimates of patients with multiple sclerosis and their physicians: comparison to an online analytical risk counseling tool.

    Directory of Open Access Journals (Sweden)

    Christoph Heesen

    Full Text Available BACKGROUND: Prognostic counseling in multiple sclerosis (MS is difficult because of the high variability of disease progression. Simultaneously, patients and physicians are increasingly confronted with making treatment decisions at an early stage, which requires taking individual prognoses into account to strike a good balance between benefits and harms of treatments. It is therefore important to understand how patients and physicians estimate prognostic risk, and whether and how these estimates can be improved. An online analytical processing (OLAP tool based on pooled data from placebo cohorts of clinical trials offers short-term prognostic estimates that can be used for individual risk counseling. OBJECTIVE: The aim of this study was to clarify if personalized prognostic information as presented by the OLAP tool is considered useful and meaningful by patients. Furthermore, we used the OLAP tool to evaluate patients' and physicians' risk estimates. Within this evaluation process we assessed short-time prognostic risk estimates of patients with MS (final n = 110 and their physicians (n = 6 and compared them with the estimates of OLAP. RESULTS: Patients rated the OLAP tool as understandable and acceptable, but to be only of moderate interest. It turned out that patients, physicians, and the OLAP tool ranked patients similarly regarding their risk of disease progression. Both patients' and physicians' estimates correlated most strongly with those disease covariates that the OLAP tool's estimates also correlated with most strongly. Exposure to the OLAP tool did not change patients' risk estimates. CONCLUSION: While the OLAP tool was rated understandable and acceptable, it was only of modest interest and did not change patients' prognostic estimates. The results suggest, however, that patients had some idea regarding their prognosis and which factors were most important in this regard. Future work with OLAP should assess long-term prognostic

  8. Prognostic risk estimates of patients with multiple sclerosis and their physicians: comparison to an online analytical risk counseling tool.

    Science.gov (United States)

    Heesen, Christoph; Gaissmaier, Wolfgang; Nguyen, Franziska; Stellmann, Jan-Patrick; Kasper, Jürgen; Köpke, Sascha; Lederer, Christian; Neuhaus, Anneke; Daumer, Martin

    2013-01-01

    Prognostic counseling in multiple sclerosis (MS) is difficult because of the high variability of disease progression. Simultaneously, patients and physicians are increasingly confronted with making treatment decisions at an early stage, which requires taking individual prognoses into account to strike a good balance between benefits and harms of treatments. It is therefore important to understand how patients and physicians estimate prognostic risk, and whether and how these estimates can be improved. An online analytical processing (OLAP) tool based on pooled data from placebo cohorts of clinical trials offers short-term prognostic estimates that can be used for individual risk counseling. The aim of this study was to clarify if personalized prognostic information as presented by the OLAP tool is considered useful and meaningful by patients. Furthermore, we used the OLAP tool to evaluate patients' and physicians' risk estimates. Within this evaluation process we assessed short-time prognostic risk estimates of patients with MS (final n = 110) and their physicians (n = 6) and compared them with the estimates of OLAP. Patients rated the OLAP tool as understandable and acceptable, but to be only of moderate interest. It turned out that patients, physicians, and the OLAP tool ranked patients similarly regarding their risk of disease progression. Both patients' and physicians' estimates correlated most strongly with those disease covariates that the OLAP tool's estimates also correlated with most strongly. Exposure to the OLAP tool did not change patients' risk estimates. While the OLAP tool was rated understandable and acceptable, it was only of modest interest and did not change patients' prognostic estimates. The results suggest, however, that patients had some idea regarding their prognosis and which factors were most important in this regard. Future work with OLAP should assess long-term prognostic estimates and clarify its usefulness for patients and physicians

  9. Pre-aggregation for Probability Distributions

    DEFF Research Database (Denmark)

    Timko, Igor; Dyreson, Curtis E.; Pedersen, Torben Bach

    Motivated by the increasing need to analyze complex uncertain multidimensional data (e.g., in order to optimize and personalize location-based services), this paper proposes novel types of {\\em probabilistic} OLAP queries that operate on aggregate values that are probability distributions...... and the techniques to process these queries. The paper also presents the methods for computing the probability distributions, which enables pre-aggregation, and for using the pre-aggregated distributions for further aggregation. In order to achieve good time and space efficiency, the methods perform approximate...... multidimensional data analysis that is considered in this paper (i.e., approximate processing of probabilistic OLAP queries over probability distributions)....

  10. Detecting summarizability in OLAP

    CERN Document Server

    Niemi, Tapio; Thanisch, Peter; Nummenmaa, Jyrki

    2014-01-01

    The industry trend towards self-service business intelligence is impeded by the absence, in commercially-available information systems, of automated identification of potential issues with summarization operations. Research on statistical databases and on data warehouses have both produced widely-accepted categorisations of measure attributes, the former based on general summarizability properties and the latter based on measures' additivity properties. We demonstrate that neither of these categorisations is an appropriate basis for precise identification of measure types since they are incomplete, ambiguous and insufficiently refined. Using a new categorisation of dimension types and multidimensional structures, we derive a measure categorisation which is a synthesis and a refinement of the two aforementioned categorisations. We give formal definitions for our summarizability types, based on the relational model of data, and then construct rules for correct summarization by using these definitions. We also g...

  11. Analytic Expression of Arbitrary Matrix Elements for Boson Exponential Quadratic Polynomial Operators

    Institute of Scientific and Technical Information of China (English)

    XU Xiu-Wei; REN Ting-Qi; LIU Shu-Yan; MA Qiu-Ming; LIU Sheng-Dian

    2007-01-01

    Making use of the transformation relation among usual, normal, and antinormal ordering for the multimode boson exponential quadratic polynomial operators (BEQPO's), we present the analytic expression of arbitrary matrix elements for BEQPO's. As a preliminary application, we obtain the exact expressions of partition function about the boson quadratic polynomial system, matrix elements in particle-number, coordinate, and momentum representation, and P representation for the BEQPO's.

  12. High-level expression of Bacillus naganoensis pullulanase from recombinant Escherichia coli with auto-induction: effect of lac operator.

    Directory of Open Access Journals (Sweden)

    Yao Nie

    Full Text Available Pullulanase plays an important role in specific hydrolysis of branch points in amylopectin and is generally employed as an important enzyme in starch-processing industry. So far, however, the production level of pullulanase is still somewhat low from wide-type strains and even heterologous expression systems. Here the gene encoding Bacillus naganoensis pullulanase was amplified and cloned. For expression of the protein, two recombinant systems, Escherichia coli BL21(DE3/pET-20b(+-pul and E. coli BL21(DE3/pET-22b(+-pul, were constructed, both bearing T7 promoter and signal peptide sequence, but different in the existance of lac operator and lacI gene encoding lac repressor. Recombinant pullulanase was initially expressed with the activity of up to 14 U/mL by E. coli BL21(DE3/pET-20b(+-pul with IPTG induction in LB medium, but its expression level reduced continually with the extension of cryopreservation time and basal expression was observed. However, E. coli BL21(DE3/pET-22b(+-pul , involving lac operator downstream of T7 promoter to regulate foreign gene transcription, exhibited pullulanase activity consistently without detected basal expression. By investigating the effect of lac operator, basal expression of foreign protein was found to cause expression instability and negative effect on production of target protein. Thus double-repression strategy was proposed that lac operators in both chromosome and plasmid were bound with lac repressor to repress T7 RNA polymerase synthesis and target protein expression before induction. Consequently, the total activity of pullulanase was remarkably increased to 580 U/mL with auto-induction by lac operator-involved E. coli BL21(DE3/pET-22b(+-pul. When adding 0.6% glycine in culture, the extracellular production of pullulanase was significantly improved with the extracellular activity of 502 U/mL, which is a relatively higher level achieved to date for extracellular production of pullulanase. The

  13. OLAP-технологии как инструментарий поддержки принятия решений

    OpenAIRE

    Акушко, Д. В.

    2017-01-01

    Настоящая статья раскрывает базовые принципы работы с OLAP-технологиями, демонстрирует ключевые особенности по сравнению с традиционными системами отчетности. Рассмотрена упрощенная структура OLAP-куба для анализа себестоимости продукции сталеплавильного цеха.

  14. List length and overlap effects in forced-choice associative recognition.

    Science.gov (United States)

    Clark, S E; Hori, A

    1995-07-01

    Two experiments examined forced-choice associative recognition for OLAP and NOLAP test conditions. OLAP test trials consist of pairs with overlapping items (e.g., AB vs. AD), whereas NOLAP test trials contain no overlapping items (e.g., AB vs. CF). Previous results show better performance for NOLAP than for OLAP tests, contrary to the predictions of global memory models. The present experiments varied list length to examine the hypothesis that the NOLAP advantage is produced by recall-like retrieval processes. The use of longer lists either eliminated (Experiment 1) or greatly reduced (Experiment 2) the NOLAP advantage. However, a reliable OLAP advantage was not obtained. Implications for models are discussed.

  15. Information integration for a sky survey by data warehousing

    Science.gov (United States)

    Luo, A.; Zhang, Y.; Zhao, Y.

    The virtualization service of data system for a sky survey LAMOST is very important for astronomers The service needs to integrate information from data collections catalogs and references and support simple federation of a set of distributed files and associated metadata Data warehousing has been in existence for several years and demonstrated superiority over traditional relational database management systems by providing novel indexing schemes that supported efficient on-line analytical processing OLAP of large databases Now relational database systems such as Oracle etc support the warehouse capability which including extensions to the SQL language to support OLAP operations and a number of metadata management tools have been created The information integration of LAMOST by applying data warehousing is to effectively provide data and knowledge on-line

  16. Dimensional enrichment of statistical linked open data

    DEFF Research Database (Denmark)

    Varga, Jovan; Vaisman, Alejandro; Romero, Oscar

    2016-01-01

    On-Line Analytical Processing (OLAP) is a data analysis technique typically used for local and well-prepared data. However, initiatives like Open Data and Open Government bring new and publicly available data on the web that are to be analyzed in the same way. The use of semantic web technologies...... for this context is especially encouraged by the Linked Data initiative. There is already a considerable amount of statistical linked open data sets published using the RDF Data Cube Vocabulary (QB) which is designed for these purposes. However, QB lacks some essential schema constructs (e.g., dimension levels......) to support OLAP. Thus, the QB4OLAP vocabulary has been proposed to extend QB with the necessary constructs and be fully compliant with OLAP. In this paper, we focus on the enrichment of an existing QB data set with QB4OLAP semantics. We first thoroughly compare the two vocabularies and outline the benefits...

  17. Performance of direct and iterative algorithms on an optical systolic processor

    Science.gov (United States)

    Ghosh, A. K.; Casasent, D.; Neuman, C. P.

    1985-11-01

    The frequency-multiplexed optical linear algebra processor (OLAP) is treated in detail with attention to its performance in the solution of systems of linear algebraic equations (LAEs). General guidelines suitable for most OLAPs, including digital-optical processors, are advanced concerning system and component error source models, guidelines for appropriate use of direct and iterative algorithms, the dominant error sources, and the effect of multiple simultaneous error sources. Specific results are advanced on the quantitative performance of both direct and iterative algorithms in the solution of systems of LAEs and in the solution of nonlinear matrix equations. Acoustic attenuation is found to dominate iterative algorithms and detector noise to dominate direct algorithms. The effect of multiple spatial errors is found to be additive. A theoretical expression for the amount of acoustic attenuation allowed is advanced and verified. Simulations and experimental data are included.

  18. Accuracies Of Optical Processors For Adaptive Optics

    Science.gov (United States)

    Downie, John D.; Goodman, Joseph W.

    1992-01-01

    Paper presents analysis of accuracies and requirements concerning accuracies of optical linear-algebra processors (OLAP's) in adaptive-optics imaging systems. Much faster than digital electronic processor and eliminate some residual distortion. Question whether errors introduced by analog processing of OLAP overcome advantage of greater speed. Paper addresses issue by presenting estimate of accuracy required in general OLAP that yields smaller average residual aberration of wave front than digital electronic processor computing at given speed.

  19. Store-operated Ca2+ Entry Modulates the Expression of Enamel Genes.

    Science.gov (United States)

    Nurbaeva, M K; Eckstein, M; Snead, M L; Feske, S; Lacruz, R S

    2015-10-01

    Dental enamel formation is an intricate process tightly regulated by ameloblast cells. The correct spatiotemporal patterning of enamel matrix protein (EMP) expression is fundamental to orchestrate the formation of enamel crystals, which depend on a robust supply of Ca2+. In the extracellular milieu, Ca2+ -EMP interactions occur at different levels. Despite its recognized role in enamel development, the molecular machinery involved in Ca2+ homeostasis in ameloblasts remains poorly understood. A common mechanism for Ca2+ influx is store-operated Ca2+ entry (SOCE). We evaluated the possibility that Ca2+ influx in enamel cells might be mediated by SOCE and the Ca2+ release-activated Ca2+ (CRAC) channel, the prototypical SOCE channel. Using ameloblast-like LS8 cells, we demonstrate that these cells express Ca2+ -handling molecules and mediate Ca2+ influx through SOCE. As a rise in the cytosolic Ca2+ concentration is a versatile signal that can modulate gene expression, we assessed whether SOCE in enamel cells had any effect on the expression of EMPs. Our results demonstrate that stimulating LS8 cells or murine primary enamel organ cells with thapsigargin to activate SOCE leads to increased expression of Amelx, Ambn, Enam, Mmp20. This effect is reversed when cells are treated with a CRAC channel inhibitor. These data indicate that Ca2+ influx in LS8 cells and enamel organ cells is mediated by CRAC channels and that Ca2+ signals enhance the expression of EMPs. Ca2+ plays an important role not only in mineralizing dental enamel but also in regulating the expression of EMPs. © International & American Associations for Dental Research 2015.

  20. Discovering Multidimensional Structure in Relational Data

    DEFF Research Database (Denmark)

    Jensen, Mikael Rune; Holmgren, Thomas; Pedersen, Torben Bach

    2004-01-01

    On-Line Analytical Processing (OLAP) systems based on multidimensional databases are essential elements of decision support. However, most existing data is stored in “ordinary” relational OLTP databases, i.e., data has to be (re-) modeled as multidimensional cubes before the advantages of OLAP to...... algorithms for discovering multidimensional schemas from relational databases. The algorithms take a wide range of available metadata into account in the discovery process, including functional and inclusion dependencies, and key and cardinality information....... tools are available. In this paper we present an approach for the automatic construction of multidimensional OLAP database schemas from existing relational OLTP databases, enabling easy OLAP design and analysis for most existing data sources. This is achieved through a set of practical and effective...

  1. Development of SOVAT: a numerical-spatial decision support system for community health assessment research.

    Science.gov (United States)

    Scotch, Matthew; Parmanto, Bambang

    2006-01-01

    The development of numerical-spatial routines is frequently required to solve complex community health problems. Community health assessment (CHA) professionals who use information technology need a complete system that is capable of supporting the development of numerical-spatial routines. Currently, there is no decision support system (DSS) that is effectively able to accomplish this task as the majority of public health geospatial information systems (GIS) are based on traditional (relational) database architecture. On-Line Analytical Processing (OLAP) is a multidimensional data warehouse technique that is commonly used as a decision support system in standard industry. OLAP alone is not sufficient for solving numerical-spatial problems that frequently occur in CHA research. Coupling it with GIS technology offers the potential for a very powerful and useful system. A community health OLAP cube was created by integrating health and population data from various sources. OLAP and GIS technologies were then combined to develop the Spatial OLAP Visualization and Analysis Tool (SOVAT). The synergy of numerical and spatial environments within SOVAT is shown through an elaborate and easy-to-use drag and drop and direct manipulation graphical user interface (GUI). Community health problem-solving examples (routines) using SOVAT are shown through a series of screen shots. The impact of the difference between SOVAT and existing GIS public health applications can be seen by considering the numerical-spatial problem-solving examples. These examples are facilitated using OLAP-GIS functions. These functions can be mimicked in existing GIS public applications, but their performance and system response would be significantly worse since GIS is based on traditional (relational) backend. OLAP-GIS system offer great potential for powerful numerical-spatial decision support in community health analysis. The functionality of an OLAP-GIS system has been shown through a series of

  2. Prognosis of the individual course of disease--steps in developing a decision support tool for Multiple Sclerosis.

    Science.gov (United States)

    Daumer, M; Neuhaus, A; Lederer, C; Scholz, M; Wolinsky, J S; Heiderhoff, M

    2007-05-08

    Multiple sclerosis is a chronic disease of uncertain aetiology. Variations in its disease course make it difficult to impossible to accurately determine the prognosis of individual patients. The Sylvia Lawry Centre for Multiple Sclerosis Research (SLCMSR) developed an "online analytical processing (OLAP)" tool that takes advantage of extant clinical trials data and allows one to model the near term future course of this chronic disease for an individual patient. For a given patient the most similar patients of the SLCMSR database are intelligently selected by a model-based matching algorithm integrated into an OLAP-tool to enable real time, web-based statistical analyses. The underlying database (last update April 2005) contains 1,059 patients derived from 30 placebo arms of controlled clinical trials. Demographic information on the entire database and the portion selected for comparison are displayed. The result of the statistical comparison is provided as a display of the course of Expanded Disability Status Scale (EDSS) for individuals in the database with regions of probable progression over time, along with their mean relapse rate. Kaplan-Meier curves for time to sustained progression in the EDSS and time to requirement of constant assistance to walk (EDSS 6) are also displayed. The software-application OLAP anticipates the input MS patient's course on the basis of baseline values and the known course of disease for similar patients who have been followed in clinical trials. This simulation could be useful for physicians, researchers and other professionals who counsel patients on therapeutic options. The application can be modified for studying the natural history of other chronic diseases, if and when similar datasets on which the OLAP operates exist.

  3. Prognosis of the individual course of disease - steps in developing a decision support tool for Multiple Sclerosis

    Science.gov (United States)

    Daumer, M; Neuhaus, A; Lederer, C; Scholz, M; Wolinsky, JS; Heiderhoff, M

    2007-01-01

    Background Multiple sclerosis is a chronic disease of uncertain aetiology. Variations in its disease course make it difficult to impossible to accurately determine the prognosis of individual patients. The Sylvia Lawry Centre for Multiple Sclerosis Research (SLCMSR) developed an "online analytical processing (OLAP)" tool that takes advantage of extant clinical trials data and allows one to model the near term future course of this chronic disease for an individual patient. Results For a given patient the most similar patients of the SLCMSR database are intelligently selected by a model-based matching algorithm integrated into an OLAP-tool to enable real time, web-based statistical analyses. The underlying database (last update April 2005) contains 1,059 patients derived from 30 placebo arms of controlled clinical trials. Demographic information on the entire database and the portion selected for comparison are displayed. The result of the statistical comparison is provided as a display of the course of Expanded Disability Status Scale (EDSS) for individuals in the database with regions of probable progression over time, along with their mean relapse rate. Kaplan-Meier curves for time to sustained progression in the EDSS and time to requirement of constant assistance to walk (EDSS 6) are also displayed. The software-application OLAP anticipates the input MS patient's course on the basis of baseline values and the known course of disease for similar patients who have been followed in clinical trials. Conclusion This simulation could be useful for physicians, researchers and other professionals who counsel patients on therapeutic options. The application can be modified for studying the natural history of other chronic diseases, if and when similar datasets on which the OLAP operates exist. PMID:17488517

  4. CD117 expression in operable oesophageal squamous cell carcinomas predicts worse clinical outcome

    Science.gov (United States)

    Fan, Huijie; Yuan, Yuan; Wang, Junsheng; Zhou, Fuyou; Zhang, Mingzhi; Giercksky, Karl-Erik; Nesland, Jahn M; Suo, Zhenhe

    2013-01-01

    Aims To investigate the aberrant expression of CD117 in oesophageal squamous cell carcinoma (SCC) and its prognostic significance. Methods and results Immunohistochemical staining for CD117 was performed on tissue microarray and routine tissue sections from 157 oesophageal SCC patients and 10 normal oesophageal epithelia adjacent to tumour. The positive rate of CD117 expression was 29.9% in oesophageal SCC tissues, whereas no CD117 expression was detected in the 10 normal oesophageal epithelia. CD117 expression was significantly associated with T stage (P < 0.001), distant metastasis (P = 0.015), lymph node metastasis (P = 0.019), and clinical stage (P = 0.021). Progression-free survival in the patients with CD117-positive tumours was shorter than that in the patients with CD117-negative tumours (P = 0.010). In univariate analyses, CD117 expression was the most significant factor for overall survival of oesophageal SCC patients (P < 0.001), followed by lymph node metastasis (P = 0.001), T stage (P = 0.002), clinical stage (P = 0.006), distant metastasis (P = 0.020), and histological grade (P = 0.027). Multivariate analyses verified that CD117 expression was an independent prognostic marker for oesophageal SCC patients (P = 0.002). In addition, CD117 expression predicted poorer survival in patients without distant metastases. Conclusions CD117 expression in operable oesophageal SCC may be a valuable prognostic marker, and detection of its expression in clinical samples may be useful in defining a subclass of oesophageal SCCs with extremely poor clinical outcome, which may require a specially targeted treatment modality. PMID:23570416

  5. Efficient Storage and Querying of Horizontal Tables Using a PIVOT Operation in Commercial Relational DBMSs

    Science.gov (United States)

    Shin, Sung-Hyun; Moon, Yang-Sae; Kim, Jinho; Kim, Sang-Wook

    In recent years, a horizontal table with a large number of attributes is widely used in OLAP or e-business applications to analyze multidimensional data efficiently. For efficient storing and querying of horizontal tables, recent works have tried to transform a horizontal table to a traditional vertical table. Existing works, however, have the drawback of not considering an optimized PIVOT operation provided (or to be provided) in recent commercial RDBMSs. In this paper we propose a formal approach that exploits the optimized PIVOT operation of commercial RDBMSs for storing and querying of horizontal tables. To achieve this goal, we first provide an overall framework that stores and queries a horizontal table using an equivalent vertical table. Under the proposed framework, we then formally define 1) a method that stores a horizontal table in an equivalent vertical table and 2) a PIVOT operation that converts a stored vertical table to an equivalent horizontal view. Next, we propose a novel method that transforms a user-specified query on horizontal tables to an equivalent PIVOT-included query on vertical tables. In particular, by providing transformation rules for all five elementary operations in relational algebra as theorems, we prove our method is theoretically applicable to commercial RDBMSs. Experimental results show that, compared with the earlier work, our method reduces storage space significantly and also improves average performance by several orders of magnitude. These results indicate that our method provides an excellent framework to maximize performance in handling horizontal tables by exploiting the optimized PIVOT operation in commercial RDBMSs.

  6. Gelation of covalently edge-modified laponites in aqueous media. 1. rheology and nuclear magnetic resonance.

    Science.gov (United States)

    Patil, Suhas P; Mathew, Renny; Ajithkumar, T G; Rajamohanan, P R; Mahesh, T S; Kumaraswamy, Guruswamy

    2008-04-17

    We describe the covalent modification of the edges of laponite with organic groups and the influence of this modification on gelation behavior. We compare three materials: an unmodified laponite, a laponite edge modified with a trimethyl moiety (MLap), and an octyldimethyl moiety (OLap). Gelation is investigated using rheology and NMR T1 relaxation measurements and nuclear Overhauser enhancement spectroscopy (NOESY). MLap and OLap show qualitatively different gelation. Gelation of MLap is very similar to laponite: MLap gels over the same time scale as laponite and has about the same solid modulus, and the MLap gel is almost as transparent as laponite. In contrast, OLap gels rapidly relative to laponite and forms a weak, turbid gel. We believe that gelation in laponite and MLap results from the formation of a network of well-dispersed platelets (or a few platelets), while in OLap, gelation results from a network of stacks of several platelets. NMR relaxation measurements indicate that gelation does not affect the average relaxation of water protons. However, T1 increases marginally for the protons in the organic moieties in MLap and decreases for protons in the organic moieties in OLap. Relaxation measurements, analyses of line width, and NOESY taken together suggest that, in OLap, gelation is a consequence of association of the organic moieties on the laponite edges, and that this association strengthens with time. Thus, the time-dependent changes in NMR suggest a structural origin for the time-dependent changes in the rheological behavior.

  7. Bounds on achievable accuracy in analog optical linear-algebra processors

    Science.gov (United States)

    Batsell, Stephen G.; Walkup, John F.; Krile, Thomas F.

    1990-07-01

    Upper arid lower bounds on the number of bits of accuracy achievable are determined by applying a seconth-ortler statistical model to the linear algebra processor. The use of bounds was found necessary due to the strong signal-dependence of the noise at the output of the optical linear algebra processor (OLAP). 1 1. ACCURACY BOUNDS One of the limiting factors in applying OLAPs to real world problems has been the poor achievable accuracy of these processors. Little previous research has been done on determining noise sources from a systems perspective which would include noise generated in the multiplication ard addition operations spatial variations across arrays and crosstalk. We have previously examined these noise sources and determined a general model for the output noise mean and variance. The model demonstrates a strony signaldependency in the noise at the output of the processor which has been confirmed by our experiments. 1 We define accuracy similar to its definition for an analog signal input to an analog-to-digital (ND) converter. The number of bits of accuracy achievable is related to the log (base 2) of the number of separable levels at the P/D converter output. The number of separable levels is fouri by dividing the dynamic range by m times the standard deviation of the signal a. 2 Here m determines the error rate in the P/D conversion. The dynamic range can be expressed as the

  8. Optical Finite Element Processor

    Science.gov (United States)

    Casasent, David; Taylor, Bradley K.

    1986-01-01

    A new high-accuracy optical linear algebra processor (OLAP) with many advantageous features is described. It achieves floating point accuracy, handles bipolar data by sign-magnitude representation, performs LU decomposition using only one channel, easily partitions and considers data flow. A new application (finite element (FE) structural analysis) for OLAPs is introduced and the results of a case study presented. Error sources in encoded OLAPs are addressed for the first time. Their modeling and simulation are discussed and quantitative data are presented. Dominant error sources and the effects of composite error sources are analyzed.

  9. Benchmarking transaction and analytical processing systems the creation of a mixed workload benchmark and its application

    CERN Document Server

    Bog, Anja

    2014-01-01

    This book introduces a new benchmark for hybrid database systems, gauging the effect of adding OLAP to an OLTP workload and analyzing the impact of commonly used optimizations in historically separate OLTP and OLAP domains in mixed-workload scenarios.

  10. Orbital Express mission operations planning and resource management using ASPEN

    Science.gov (United States)

    Chouinard, Caroline; Knight, Russell; Jones, Grailing; Tran, Daniel

    2008-04-01

    As satellite equipment and mission operations become more costly, the drive to keep working equipment running with less labor-power rises. Demonstrating the feasibility of autonomous satellite servicing was the main goal behind the Orbital Express (OE) mission. Like a tow-truck delivering gas to a car on the road, the "servicing" satellite of OE had to find the "client" from several kilometers away, connect directly to the client, and transfer fluid (or a battery) autonomously, while on earth-orbit. The mission met 100% of its success criteria, and proved that autonomous satellite servicing is now a reality for space operations. Planning the satellite mission operations for OE required the ability to create a plan which could be executed autonomously over variable conditions. As the constraints for execution could change weekly, daily, and even hourly, the tools used create the mission execution plans needed to be flexible and adaptable to many different kinds of changes. At the same time, the hard constraints of the plans needed to be maintained and satisfied. The Automated Scheduling and Planning Environment (ASPEN) tool, developed at the Jet Propulsion Laboratory, was used to create the schedule of events in each daily plan for the two satellites of the OE mission. This paper presents an introduction to the ASPEN tool, an overview of the constraints of the OE domain, the variable conditions that were presented within the mission, and the solution to operations that ASPEN provided. ASPEN has been used in several other domains, including research rovers, Deep Space Network scheduling research, and in flight operations for the NASA's Earth Observing One mission's EO1 satellite. Related work is discussed, as are the future of ASPEN and the future of autonomous satellite servicing.

  11. Prognosis of the individual course of disease - steps in developing a decision support tool for Multiple Sclerosis

    Directory of Open Access Journals (Sweden)

    Scholz M

    2007-05-01

    Full Text Available Abstract Background Multiple sclerosis is a chronic disease of uncertain aetiology. Variations in its disease course make it difficult to impossible to accurately determine the prognosis of individual patients. The Sylvia Lawry Centre for Multiple Sclerosis Research (SLCMSR developed an "online analytical processing (OLAP" tool that takes advantage of extant clinical trials data and allows one to model the near term future course of this chronic disease for an individual patient. Results For a given patient the most similar patients of the SLCMSR database are intelligently selected by a model-based matching algorithm integrated into an OLAP-tool to enable real time, web-based statistical analyses. The underlying database (last update April 2005 contains 1,059 patients derived from 30 placebo arms of controlled clinical trials. Demographic information on the entire database and the portion selected for comparison are displayed. The result of the statistical comparison is provided as a display of the course of Expanded Disability Status Scale (EDSS for individuals in the database with regions of probable progression over time, along with their mean relapse rate. Kaplan-Meier curves for time to sustained progression in the EDSS and time to requirement of constant assistance to walk (EDSS 6 are also displayed. The software-application OLAP anticipates the input MS patient's course on the basis of baseline values and the known course of disease for similar patients who have been followed in clinical trials. Conclusion This simulation could be useful for physicians, researchers and other professionals who counsel patients on therapeutic options. The application can be modified for studying the natural history of other chronic diseases, if and when similar datasets on which the OLAP operates exist.

  12. 数据仓库与OLAP在通信线路状态统计中的应用%Application of Data Warehouse and OLAP in Preference Data Analysis on Communication Line State Statistics

    Institute of Scientific and Technical Information of China (English)

    刘淑娟; 岳鹏

    2012-01-01

    In recent years, with the rapid development of the communication industry, more and more broadband accessed. Customers on the bandwidth and broadband quality put forward higher requirement, how to reduce the operation and maintenance costs, and improve network quality are the biggest problem for corporations. So corporations must have a whole understanding for the communication line state. As the above problems, this paper according to the enterprise to communication line state statistics demand, through the application of data warehouse and OLAP technology for the original communication lines state statistics the multi-dimensional data analysis, makes a practical scheme for line state statistical. This plan can offer reference in telecommunications companies in line state statistics.%近年来,随着通信行业的飞速发展,宽带接入的用户越来越多.客户对带宽和宽带的质量提出更高的要求,如何降低运营成本,提升网络质量,是宽带运营商运行维护面临的最大问题.因此,企业必须对通信线路的运行维护状况有一个整体的了解.本文针对以上的问题,根据企业对通信线路状态统计的需求,通过运用数据仓库及OLAP技术,对原有的通信线路状态统计的相关数据进行多维分析,制定一套切实可行的线路状态统计方案,此方案可供通信企业在线路状态统计中参考.

  13. Explanatory analysis in business intelligence systems

    NARCIS (Netherlands)

    Caron, E.A.M.; Daniëls, H.A.M.; Dinter, B.; Smolnik, S.

    2012-01-01

    In this paper we describe a method for the discovery of exceptional values in business intelligence (BI) systems, in particular OLAP information systems. We also show how exceptional values can be explained by underlying causes. OLAP applications offer a support tool for business analysts and

  14. Solutions for medical databases optimal exploitation.

    Science.gov (United States)

    Branescu, I; Purcarea, V L; Dobrescu, R

    2014-03-15

    The paper discusses the methods to apply OLAP techniques for multidimensional databases that leverage the existing, performance-enhancing technique, known as practical pre-aggregation, by making this technique relevant to a much wider range of medical applications, as a logistic support to the data warehousing techniques. The transformations have practically low computational complexity and they may be implemented using standard relational database technology. The paper also describes how to integrate the transformed hierarchies in current OLAP systems, transparently to the user and proposes a flexible, "multimodel" federated system for extending OLAP querying to external object databases.

  15. Orbital Express Mission Operations Planning and Resource Management using ASPEN

    Science.gov (United States)

    Chouinard, Caroline; Knight, Russell; Jones, Grailing; Tran, Danny

    2008-01-01

    The Orbital Express satellite servicing demonstrator program is a DARPA program aimed at developing "a safe and cost-effective approach to autonomously service satellites in orbit". The system consists of: a) the Autonomous Space Transport Robotic Operations (ASTRO) vehicle, under development by Boeing Integrated Defense Systems, and b) a prototype modular next-generation serviceable satellite, NEXTSat, being developed by Ball Aerospace. Flexibility of ASPEN: a) Accommodate changes to procedures; b) Accommodate changes to daily losses and gains; c) Responsive re-planning; and d) Critical to success of mission planning Auto-Generation of activity models: a) Created plans quickly; b) Repetition/Re-use of models each day; and c) Guarantees the AML syntax. One SRP per day vs. Tactical team

  16. Proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013, Buenos Aires, Argentina, August 26, 2013)

    NARCIS (Netherlands)

    Borgström, J.; Luttik, B.

    2013-01-01

    This volume contains the proceedings of the Combined 20th International Workshop on Expressiveness in Concurrency and the 10th Workshop on Structural Operational Semantics (EXPRESS/SOS 2013) which was held on 26th August, 2013 in Buenos Aires, Argentina, as an affiliated workshop of CONCUR 2013, the

  17. Accuracy requirements of optical linear algebra processors in adaptive optics imaging systems

    Science.gov (United States)

    Downie, John D.; Goodman, Joseph W.

    1989-10-01

    The accuracy requirements of optical processors in adaptive optics systems are determined by estimating the required accuracy in a general optical linear algebra processor (OLAP) that results in a smaller average residual aberration than that achieved with a conventional electronic digital processor with some specific computation speed. Special attention is given to an error analysis of a general OLAP with regard to the residual aberration that is created in an adaptive mirror system by the inaccuracies of the processor, and to the effect of computational speed of an electronic processor on the correction. Results are presented on the ability of an OLAP to compete with a digital processor in various situations.

  18. Modeling of Students' Profile and Learning Chronicle with Data Cubes

    Science.gov (United States)

    Ola, Ade G.; Bai, Xue; Omojokun, Emmanuel E.

    2014-01-01

    Over the years, companies have relied on On-Line Analytical Processing (OLAP) to answer complex questions relating to issues in business environments such as identifying profitability, trends, correlations, and patterns. This paper addresses the application of OLAP in education and learning. The objective of the research presented in the paper is…

  19. Review: Implementasi Holap Untuk Optimasi Query Sistem Basis Data Terdistribusi Dengan Pendekatan Algoritma Genetik

    Directory of Open Access Journals (Sweden)

    Rahmad Syaifudin

    2016-01-01

    Full Text Available Distributed Database is one of database that is under control of the Database Management System (DBMS was focused on storage devices are separated from one and another. Optimization data query on distributed database system not be separated from data processing methods that used. Then for fast query optimization this database need some required methods that can optimize it. Hybrid online analytical processing (HOLAP or often to call Hybrid-OLAP is one of technology for optimization query on distributed database. Genetic Algorithm is one of algorithm for heuristic searching was based on the mechanisms of biological evolution. Process of genetic algorithm is combining a selection process, using a crossover operator and mutation to get the best solution. From the reviews about implementation HOLAP with Genetic Algorithm approach was expected being used as a basis research on HOLAP implementation for query optimization on distributed database with genetic algorithm approach. Keywords : Query Optimization; Distributed database; HOLAP; OLAP; Genetetic algorithm.

  20. Timecourse microarray analyses reveal global changes in gene expression of susceptible Glycine max (soybean) roots during infection by Heterodera glycines (soybean cyst nematode).

    Science.gov (United States)

    Alkharouf, Nadim W; Klink, Vincent P; Chouikha, Imed B; Beard, Hunter S; MacDonald, Margaret H; Meyer, Susan; Knap, Halina T; Khan, Rana; Matthews, Benjamin F

    2006-09-01

    Changes in gene expression within roots of Glycine max (soybean), cv. Kent, susceptible to infection by Heterodera glycines (the soybean cyst nematode [SCN]), at 6, 12, and 24 h, and 2, 4, 6, and 8 days post-inoculation were monitored using microarrays containing more than 6,000 cDNA inserts. Replicate, independent biological samples were examined at each time point. Gene expression was analyzed statistically using T-tests, ANOVA, clustering algorithms, and online analytical processing (OLAP). These analyses allow the user to query the data in several ways without importing the data into third-party software. RT-PCR confirmed that WRKY6 transcription factor, trehalose phosphate synthase, EIF4a, Skp1, and CLB1 were differentially induced across most time-points. Other genes induced across most timepoints included lipoxygenase, calmodulin, phospholipase C, metallothionein-like protein, and chalcone reductase. RT-PCR demonstrated enhanced expression during the first 12 h of infection for Kunitz trypsin inhibitor and sucrose synthase. The stress-related gene, SAM-22, phospholipase D and 12-oxophytodienoate reductase were also induced at the early time-points. At 6 and 8 dpi there was an abundance of transcripts expressed that encoded genes involved in transcription and protein synthesis. Some of those genes included ribosomal proteins, and initiation and elongation factors. Several genes involved in carbon metabolism and transport were also more abundant. Those genes included glyceraldehyde 3-phosphate dehydrogenase, fructose-bisphosphate aldolase and sucrose synthase. These results identified specific changes in gene transcript levels triggered by infection of susceptible soybean roots by SCN.

  1. Data warehouse based decision support system in nuclear power plants

    International Nuclear Information System (INIS)

    Nadinic, B.

    2004-01-01

    Safety is an important element in business decision making processes in nuclear power plants. Information about component reliability, structures and systems, data recorded during the nuclear power plant's operation and outage periods, as well as experiences from other power plants are located in different database systems throughout the power plant. It would be possible to create a decision support system which would collect data, transform it into a standardized form and store it in a single location in a format more suitable for analyses and knowledge discovery. This single location where the data would be stored would be a data warehouse. Such data warehouse based decision support system could help make decision making processes more efficient by providing more information about business processes and predicting possible consequences of different decisions. Two main functionalities in this decision support system would be an OLAP (On Line Analytical Processing) and a data mining system. An OLAP system would enable the users to perform fast, simple and efficient multidimensional analysis of existing data and identify trends. Data mining techniques and algorithms would help discover new, previously unknown information from the data as well as hidden dependencies between various parameters. Data mining would also enable analysts to create relevant prediction models that could predict behaviour of different systems during operation and inspection results during outages. The basic characteristics and theoretical foundations of such decision support system are described and the reasons for choosing a data warehouse as the underlying structure are explained. The article analyzes obvious business benefits of such system as well as potential uses of OLAP and data mining technologies. Possible implementation methodologies and problems that may arise, especially in the field of data integration, are discussed and analyzed.(author)

  2. SQL based cardiovascular ultrasound image classification.

    Science.gov (United States)

    Nandagopalan, S; Suryanarayana, Adiga B; Sudarshan, T S B; Chandrashekar, Dhanalakshmi; Manjunath, C N

    2013-01-01

    This paper proposes a novel method to analyze and classify the cardiovascular ultrasound echocardiographic images using Naïve-Bayesian model via database OLAP-SQL. Efficient data mining algorithms based on tightly-coupled model is used to extract features. Three algorithms are proposed for classification namely Naïve-Bayesian Classifier for Discrete variables (NBCD) with SQL, NBCD with OLAP-SQL, and Naïve-Bayesian Classifier for Continuous variables (NBCC) using OLAP-SQL. The proposed model is trained with 207 patient images containing normal and abnormal categories. Out of the three proposed algorithms, a high classification accuracy of 96.59% was achieved from NBCC which is better than the earlier methods.

  3. Dynameomics: a multi-dimensional analysis-optimized database for dynamic protein data.

    Science.gov (United States)

    Kehl, Catherine; Simms, Andrew M; Toofanny, Rudesh D; Daggett, Valerie

    2008-06-01

    The Dynameomics project is our effort to characterize the native-state dynamics and folding/unfolding pathways of representatives of all known protein folds by way of molecular dynamics simulations, as described by Beck et al. (in Protein Eng. Des. Select., the first paper in this series). The data produced by these simulations are highly multidimensional in structure and multi-terabytes in size. Both of these features present significant challenges for storage, retrieval and analysis. For optimal data modeling and flexibility, we needed a platform that supported both multidimensional indices and hierarchical relationships between related types of data and that could be integrated within our data warehouse, as described in the accompanying paper directly preceding this one. For these reasons, we have chosen On-line Analytical Processing (OLAP), a multi-dimensional analysis optimized database, as an analytical platform for these data. OLAP is a mature technology in the financial sector, but it has not been used extensively for scientific analysis. Our project is further more unusual for its focus on the multidimensional and analytical capabilities of OLAP rather than its aggregation capacities. The dimensional data model and hierarchies are very flexible. The query language is concise for complex analysis and rapid data retrieval. OLAP shows great promise for the dynamic protein analysis for bioengineering and biomedical applications. In addition, OLAP may have similar potential for other scientific and engineering applications involving large and complex datasets.

  4. A free software tool for the development of decision support systems

    Directory of Open Access Journals (Sweden)

    COLONESE, G

    2008-06-01

    Full Text Available This article describes PostGeoOlap, a free software open source tool for decision support that integrates OLAP (On-Line Analytical Processing and GIS (Geographical Information Systems. Besides describing the tool, we show how it can be used to achieve effective and low cost decision support that is adequate for small and medium companies and for small public offices.

  5. Метод концептуального OLAP-моделирования на основе формального концептуального анализа

    OpenAIRE

    Коробко, А.; Пенькова, Т.

    2010-01-01

    Предложен метод концептуального OLAP-моделирования предметной области. Представлено описание процесса построения интегральной аналитической модели в виде формальной концептуальной решетки OLAP-кубов. Применение концептуальной OLAP-модели позволяет повысить эффективность оперативной аналитической обработки многомерных данных. Выполнено построение концептуальной аналитической модели научной деятельности организации на основе предложенного метода....

  6. Value of post-operative reassessment of estrogen receptor α expression following neoadjuvant chemotherapy with or without gefitinib for estrogen receptor negative breast cancer

    DEFF Research Database (Denmark)

    Bernsdorf, Mogens; Balslev, Eva; Lykkesfeldt, Anne

    2011-01-01

    The NICE trial was designed to evaluate the possible benefits of adding epidermal growth factor receptor targeted therapy to neoadjuvant chemotherapy in patients with estrogen receptor α (ER) negative and operable breast cancer. Preclinical data have suggested that signalling through the Erb......B receptors or downstream effectors may repress ER expression. Here the authors investigated whether gefitinib, given neoadjuvant in combination with epirubicin and cyclophosphamide (EC), could restore ER expression. Eligible patients in the NICE trial were women with unilateral, primary operable, ER negative...... to positive. A change was seen in three patients in the gefitinib (5.1%) and in two patients in the placebo (3.6%) group with a difference of 1.51% (95% CI, -6.1-9.1). Results of the NICE trial have been reported previously. Post-operative reassessment of ER expression changed the assessment of ER status...

  7. Expressiveness modulo Bisimilarity of Regular Expressions with Parallel Composition (Extended Abstract

    Directory of Open Access Journals (Sweden)

    Jos C. M. Baeten

    2010-11-01

    Full Text Available The languages accepted by finite automata are precisely the languages denoted by regular expressions. In contrast, finite automata may exhibit behaviours that cannot be described by regular expressions up to bisimilarity. In this paper, we consider extensions of the theory of regular expressions with various forms of parallel composition and study the effect on expressiveness. First we prove that adding pure interleaving to the theory of regular expressions strictly increases its expressiveness up to bisimilarity. Then, we prove that replacing the operation for pure interleaving by ACP-style parallel composition gives a further increase in expressiveness. Finally, we prove that the theory of regular expressions with ACP-style parallel composition and encapsulation is expressive enough to express all finite automata up to bisimilarity. Our results extend the expressiveness results obtained by Bergstra, Bethke and Ponse for process algebras with (the binary variant of Kleene's star operation.

  8. A similarity-based data warehousing environment for medical images.

    Science.gov (United States)

    Teixeira, Jefferson William; Annibal, Luana Peixoto; Felipe, Joaquim Cezar; Ciferri, Ricardo Rodrigues; Ciferri, Cristina Dutra de Aguiar

    2015-11-01

    A core issue of the decision-making process in the medical field is to support the execution of analytical (OLAP) similarity queries over images in data warehousing environments. In this paper, we focus on this issue. We propose imageDWE, a non-conventional data warehousing environment that enables the storage of intrinsic features taken from medical images in a data warehouse and supports OLAP similarity queries over them. To comply with this goal, we introduce the concept of perceptual layer, which is an abstraction used to represent an image dataset according to a given feature descriptor in order to enable similarity search. Based on this concept, we propose the imageDW, an extended data warehouse with dimension tables specifically designed to support one or more perceptual layers. We also detail how to build an imageDW and how to load image data into it. Furthermore, we show how to process OLAP similarity queries composed of a conventional predicate and a similarity search predicate that encompasses the specification of one or more perceptual layers. Moreover, we introduce an index technique to improve the OLAP query processing over images. We carried out performance tests over a data warehouse environment that consolidated medical images from exams of several modalities. The results demonstrated the feasibility and efficiency of our proposed imageDWE to manage images and to process OLAP similarity queries. The results also demonstrated that the use of the proposed index technique guaranteed a great improvement in query processing. Copyright © 2015 Elsevier Ltd. All rights reserved.

  9. Advances and Research Directions in Data-Warehousing Technology

    Directory of Open Access Journals (Sweden)

    Mukesh Mohania

    1999-11-01

    Full Text Available Information is one of the most valuable assets of an organisation and when used properly can assist in intelligent decision making that can significantly improve the functioning of an organisation. Data Warehousing is a recent technology that allows information to be easily and efficiently accessed for decision-making activities by collecting data from many operational, legacy and possibly heterogeneous data sources. On-Line Analytical Processing (OLAP tools are well-suited for complex data analysis, such as multi-dimensional data analysis, and to assist in decision support activities while data mining tools take the process one step further and actively search the data for patterns and hidden knowledge in the data held in the warehouse. Many organisations are building, or are planning to develop, a data warehouse for their operational and decision support needs. In this paper, we present an overview of data warehousing, multi-dimensional databases, OLAP and data mining technology and discuss the directions of current research in the area. We also discuss recent developments in data warehouse modelling, view selection and maintenance, indexing schemes, parallel query processing and data mining issues. A number of technical issues for exploratory research are presented and possible solutions are also discussed.

  10. Expressing stochastic unravellings using random evolution operators

    International Nuclear Information System (INIS)

    Salgado, D; Sanchez-Gomez, J L

    2002-01-01

    We prove how the form of the most general invariant stochastic unravelling for Markovian (recently given in the literature by Wiseman and Diosi) and non-Markovian but Lindblad-type open quantum systems can be attained by imposing a single mathematical condition upon the random evolution operator of the system, namely a.s. trace preservation (a.s. stands for almost surely). The use of random operators ensures the complete positivity of the density operator evolution and characterizes the linear/non-linear character of the evolution in a straightforward way. It is also shown how three quantum stochastic evolution models - continuous spontaneous localization, quantum state diffusion and quantum mechanics with universal position localization - appear as concrete choices for the noise term of the evolution random operators are assumed. We finally conjecture how these operators may in the future be used in two different directions: both to connect quantum stochastic evolution models with random properties of space-time and to handle noisy quantum logical gates

  11. INFORMATION MODEL OF MAJOR DEPRESSION TREATMENT COST - RELEVANCE OF QUALITY MANAGEMENT OF HEALTH SYSTEM

    Directory of Open Access Journals (Sweden)

    Danijela Tadić

    2010-09-01

    Full Text Available This paper develops multirelational data base for major depression costs. It lists how data are collected and stored into the fact base and dimension base. Uncertain data is described linguistically and modelled by fuzzy sets. Linguistic expressions are stored in dimension base. Models of major depression treatment costs are developed for each patient and all population. On the basis of this model and multirelational data base MD-OLAP a model for major depression treatment costs is developed.

  12. Rancang Bangun Sistem Business Intelligence Universitas Sebagai Pendukung Pengambilan Keputusan Akademik

    Directory of Open Access Journals (Sweden)

    Zainal Arifin

    2016-01-01

    Full Text Available Sistem business intelligence universitas dimulai dengan tahapan integrasi data, analisis data, membuat laporan dan membuatweb portal dan kemudian mengitegrasikan laporan tersebut dengan web portal. Analisis data diolah dengan OLAP, KPI dandata mining untuk mengekstrak informasi dari data yang tersimpan didalam data warehouse. Hasil proses analisis datatersebut di representasikan dalam bentuk laporan statistik dan dashboard, kemudian digunakan sebagai pendukungpengambilan keputusan akademik. Penelitian ini bertujuan merancang bangun sistem business intelligence universitassebagai pendukung pengambilan keputusan akademik pada Universitas Mulawarman berbasis web dengan OLAP. Penelitianini menghasilkan kerangka sistem dan web portal sistem business intelligence universitas yang diakses melalui browsersecara online. Business Intelligence dapat digunakan sebagai solusi untuk mempertimbangkan proses pengambilan keputusandalam pengelolaan universitas dan solusi dalam peningkatan kinerja pengelolaan akademik untuk mencapai keunggulanakademik.Kata kunci : Business Intelligence; Data warehouse; OLAP; KPI; Data mining

  13. Effect of preoperative neoadjuvant chemotherapy on the expression of malignant molecules in colon cancer tissue and the degree of trauma caused by radical operation

    Directory of Open Access Journals (Sweden)

    Yan-Cheng Wang

    2017-09-01

    Full Text Available Objective: To study the effect of preoperative neoadjuvant chemotherapy on the expression of malignant molecules in colon cancer tissue and the degree of trauma caused by radical operation. Methods: Patients who were diagnosed with colon cancer in Fengrun People’s Hospital between March 2014 and February 2017 were selected and randomly divided into the XELOX group who accepted XELOX neoadjuvant chemotherapy combined with radical operation for colon cancer and the control group who accepted radical operation for colon cancer alone. Surgically removed colon cancer tissue was collected to test the expression of proliferation, apoptosis and invasion genes, and serum was collected to detect the contents of liver and kidney function indicators as well as inflammatory factors. Results: Rac1, PLD2, CHD1L, Snail, Vimentin and N-cadherin mRNA expression levels in surgically removed colon cancer lesions of XELOX group were significantly lower than those of control group while MS4A12 and ASPP2 mRNA expression levels were significantly higher than those of control group; serum ALT, AST, β2-MG, Cys-C, sICAM-1, sVCAM-1, sTM and sE-selectin contents were not significantly different between the two groups of patients 1 day and 3 days after surgery. Conclusion: Preoperative neoadjuvant chemotherapy can inhibit the proliferation, apoptosis and invasion gene expression in colon cancer tissues without increasing the trauma of operation.

  14. Pengembangan Data Warehouse Menggunakan Pendekatan Data-Driven untuk Membantu Pengelolaan SDM

    Directory of Open Access Journals (Sweden)

    Mujiono Mujiono

    2016-01-01

    Full Text Available The basis of bureaucratic reform is the reform of human resources management. One supporting factor is the development of an employee database. To support the management of human resources required including data warehouse and business intelligent tools. The data warehouse is an integrated concept of reliable data storage to provide support to all the needs of the data analysis. In this study developed a data warehouse using the data-driven approach to the source data comes from SIMPEG, SAPK and electronic presence. Data warehouses are designed using the nine steps methodology and unified modeling language (UML notation. Extract transform load (ETL is done by using Pentaho Data Integration by applying transformation maps. Furthermore, to help human resource management, the system is built to perform online analytical processing (OLAP to facilitate web-based information. In this study generated BI application development framework with Model-View-Controller (MVC architecture and OLAP operations are built using the dynamic query generation, PivotTable, and HighChart to present information about PNS, CPNS, Retirement, Kenpa and Presence

  15. Merging OLTP and OLAP - Back to the Future

    Science.gov (United States)

    Lehner, Wolfgang

    When the terms "Data Warehousing" and "Online Analytical Processing" were coined in the 1990s by Kimball, Codd, and others, there was an obvious need for separating data and workload for operational transactional-style processing and decision-making implying complex analytical queries over large and historic data sets. Large data warehouse infrastructures have been set up to cope with the special requirements of analytical query answering for multiple reasons: For example, analytical thinking heavily relies on predefined navigation paths to guide the user through the data set and to provide different views on different aggregation levels.Multi-dimensional queries exploiting hierarchically structured dimensions lead to complex star queries at a relational backend, which could hardly be handled by classical relational systems.

  16. Use of Radcube for extraction of finding trends in a large radiology practice.

    Science.gov (United States)

    Dang, Pragya A; Kalra, Mannudeep K; Blake, Michael A; Schultz, Thomas J; Stout, Markus; Halpern, Elkan F; Dreyer, Keith J

    2009-12-01

    The purpose of our study was to demonstrate the use of Natural Language Processing (Leximer), along with Online Analytic Processing, (NLP-OLAP), for extraction of finding trends in a large radiology practice. Prior studies have validated the Natural Language Processing (NLP) program, Leximer for classifying unstructured radiology reports based on the presence of positive radiology findings (F (POS)) and negative radiology findings (F (NEG)). The F (POS) included new relevant radiology findings and any change in status from prior imaging. Electronic radiology reports from 1995-2002 and data from analysis of these reports with NLP-Leximer were saved in a data warehouse and exported to a multidimensional structure called the Radcube. Various relational queries on the data in the Radcube were performed using OLAP technique. Thus, NLP-OLAP was applied to determine trends of F (POS) in different radiology exams for different patient and examination attributes. Pivot tables were exported from NLP-OLAP interface to Microsoft Excel for statistical analysis. Radcube allowed rapid and comprehensive analysis of F (POS) and F (NEG) trends in a large radiology report database. Trends of F (POS) were extracted for different patient attributes such as age groups, gender, clinical indications, diseases with ICD codes, patient types (inpatient, ambulatory), imaging characteristics such as imaging modalities, referring physicians, radiology subspecialties, and body regions. Data analysis showed substantial differences between F (POS) rates for different imaging modalities ranging from 23.1% (mammography, 49,163/212,906) to 85.8% (nuclear medicine, 93,852/109,374; p OLAP can help in analysis of yield of different radiology exams from a large radiology report database.

  17. GeoSemOLAP

    DEFF Research Database (Denmark)

    Gur, Nurefsan; Nielsen, Jacob; Hose, Katja

    2017-01-01

    The proliferation of spatial data and the publication of multidimensional (MD) data on the Semantic Web (SW) has led to new opportunities for On-Line Analytical Processing (SOLAP) over spatial data using SPARQL. However, formulating such queries results in verbose statements and can easily become...

  18. Development of traditional Chinese medicine clinical data warehouse for medical knowledge discovery and decision support.

    Science.gov (United States)

    Zhou, Xuezhong; Chen, Shibo; Liu, Baoyan; Zhang, Runsun; Wang, Yinghui; Li, Ping; Guo, Yufeng; Zhang, Hua; Gao, Zhuye; Yan, Xiufeng

    2010-01-01

    Traditional Chinese medicine (TCM) is a scientific discipline, which develops the related theories from the long-term clinical practices. The large-scale clinical data are the core empirical knowledge source for TCM research. This paper introduces a clinical data warehouse (CDW) system, which incorporates the structured electronic medical record (SEMR) data for medical knowledge discovery and TCM clinical decision support (CDS). We have developed the clinical reference information model (RIM) and physical data model to manage the various information entities and their relationships in TCM clinical data. An extraction-transformation-loading (ETL) tool is implemented to integrate and normalize the clinical data from different operational data sources. The CDW includes online analytical processing (OLAP) and complex network analysis (CNA) components to explore the various clinical relationships. Furthermore, the data mining and CNA methods are used to discover the valuable clinical knowledge from the data. The CDW has integrated 20,000 TCM inpatient data and 20,000 outpatient data, which contains manifestations (e.g. symptoms, physical examinations and laboratory test results), diagnoses and prescriptions as the main information components. We propose a practical solution to accomplish the large-scale clinical data integration and preprocessing tasks. Meanwhile, we have developed over 400 OLAP reports to enable the multidimensional analysis of clinical data and the case-based CDS. We have successfully conducted several interesting data mining applications. Particularly, we use various classification methods, namely support vector machine, decision tree and Bayesian network, to discover the knowledge of syndrome differentiation. Furthermore, we have applied association rule and CNA to extract the useful acupuncture point and herb combination patterns from the clinical prescriptions. A CDW system consisting of TCM clinical RIM, ETL, OLAP and data mining as the core

  19. Coordinated increase in skeletal muscle fiber area and expression of IGF-I with resistance exercise in elderly post-operative patients

    DEFF Research Database (Denmark)

    Suetta, Charlotte; Clemmensen, Christoffer; Andersen, Jesper L

    2010-01-01

    Hypertrophy of developing skeletal muscle involves stimulation by insulin-like growth factor-I (IGF-I), however, the role of IGF-I in adult muscle is less clarified. In the present study, the mRNA splice variants of IGF-I (IGF-IEa and MGF) and the changes in muscle fiber cross sectional area after...... and in addition induces marked increases in the expression of IGF-I splice variants, supporting the idea that IGF-I is involved in regulating muscle hypertrophy.......-operated-side served as a within subject control. Muscle biopsies were obtained from the vastus lateralis of both limbs at +2d post-operative (baseline), at 5weeks and 12weeks post-surgery to analyze for changes in type 1 and type 2 muscle fiber area. Changes in expression levels of IGF-I mRNA isoforms were determined...

  20. Analysis and use of OLAP tools in the corporative information system of CFE; Analisis y empleo de herramientas OLAP en el sistema de informacion corporativa de la CFE

    Energy Technology Data Exchange (ETDEWEB)

    Jacome G, Norma E; Argotte R, Liliana P; Mejia L, Manuel [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)

    2003-07-01

    The commercial tools Oracle Express and Oracle the Discoverer are presented, applied and compared. Both of them were applied in the context of the Data Storage that Comision Federal de Electricidad (CFE) develops, denominated Corporative Information System (SICORP) that involves the handling of large volumes of historical and present information. By the importance and the relevance that at the moment the subject of data storage has, the experiences that are described in the article are very useful for future developments. [Spanish] Se presentan, aplican y comparan las herramientas comerciales Oracle Express y Oracle Discoverer. Ambas fueron aplicadas en el contexto del Almacen de Datos que la Comision Federal de Electricidad (CFE) desarrolla, denominado Sistema de Informacion Corporativa (Sicorp), que involucra el manejo de grandes volumenes de informacion historica y actual. Por la importancia y el auge que actualmente tiene el tema de almacenes de datos, las experiencias que se describen en el articulo son de gran utilidad para futuros desarrollos.

  1. Regulation of nif expression in Methanococcus maripaludis: roles of the euryarchaeal repressor NrpR, 2-oxoglutarate, and two operators.

    Science.gov (United States)

    Lie, Thomas J; Wood, Gwendolyn E; Leigh, John A

    2005-02-18

    The methanogenic archaean Methanococcus maripaludis can use ammonia, alanine, or dinitrogen as a nitrogen source for growth. The euryarchaeal nitrogen repressor NrpR controls the expression of the nif (nitrogen fixation) operon, resulting in full repression with ammonia, intermediate repression with alanine, and derepression with dinitrogen. NrpR binds to two tandem operators in the nif promoter region, nifOR(1) and nifOR(2). Here we have undertaken both in vivo and in vitro approaches to study the way in which NrpR, nifOR(1), nifOR(2), and the effector 2-oxoglutarate (2OG) combine to regulate nif expression, leading to a comprehensive understanding of this archaeal regulatory system. We show that NrpR binds as a dimer to nifOR(1) and cooperatively as two dimers to both operators. Cooperative binding occurs only with both operators present. nifOR(1) has stronger binding and by itself can mediate the repression of nif transcription during growth on ammonia, unlike the weakly binding nifOR(2). However, nifOR(2) in combination with nifOR(1) is critical for intermediate repression during growth on alanine. Accordingly, NrpR binds to both operators together with higher affinity than to nifOR(1) alone. NrpR responds directly to 2OG, which weakens its binding to the operators. Hence, 2OG is an intracellular indicator of nitrogen deficiency and acts as an inducer of nif transcription via NrpR. This model is upheld by the recent finding (J. A. Dodsworth and J. A. Leigh, submitted for publication) in our laboratory that 2OG levels in M. maripaludis vary with growth on different nitrogen sources.

  2. Multilinear operators for higher-order decompositions.

    Energy Technology Data Exchange (ETDEWEB)

    Kolda, Tamara Gibson

    2006-04-01

    We propose two new multilinear operators for expressing the matrix compositions that are needed in the Tucker and PARAFAC (CANDECOMP) decompositions. The first operator, which we call the Tucker operator, is shorthand for performing an n-mode matrix multiplication for every mode of a given tensor and can be employed to concisely express the Tucker decomposition. The second operator, which we call the Kruskal operator, is shorthand for the sum of the outer-products of the columns of N matrices and allows a divorce from a matricized representation and a very concise expression of the PARAFAC decomposition. We explore the properties of the Tucker and Kruskal operators independently of the related decompositions. Additionally, we provide a review of the matrix and tensor operations that are frequently used in the context of tensor decompositions.

  3. What Is Spatio-Temporal Data Warehousing?

    Science.gov (United States)

    Vaisman, Alejandro; Zimányi, Esteban

    In the last years, extending OLAP (On-Line Analytical Processing) systems with spatial and temporal features has attracted the attention of the GIS (Geographic Information Systems) and database communities. However, there is no a commonly agreed definition of what is a spatio-temporal data warehouse and what functionality such a data warehouse should support. Further, the solutions proposed in the literature vary considerably in the kind of data that can be represented as well as the kind of queries that can be expressed. In this paper we present a conceptual framework for defining spatio-temporal data warehouses using an extensible data type system. We also define a taxonomy of different classes of queries of increasing expressive power, and show how to express such queries using an extension of the tuple relational calculus with aggregated functions.

  4. Path Expressions

    Science.gov (United States)

    1975-06-01

    Traditionally, synchronization of concurrent processes is coded in line by operations on semaphores or similar objects. Path expressions move the...discussion about a variety of synchronization primitives . An analysis of their relative power is found in [3]. Path expressions do not introduce yet...another synchronization primitive . A path expression relates to such primitives as a for- or while-statement of an ALGOL-like language relates to a JUMP

  5. PERANCANGAN DATA WAREHOUSE UNTUK MENDUKUNG PERENCANAAN PEMASARAN PERGURUAN TINGGI

    Directory of Open Access Journals (Sweden)

    agung prasetyo

    2017-02-01

    Full Text Available Salah satu indikasi perguruan tinggi yang besar adalah dilihat dari jumlah mahasiswa di perguruan tinggi tersebut. Karenanya, mahasiswa baru merupakan salah satu sumber daya yang menentukan berjalannya sebuah perguruan tinggi. Setiap tahunnya STMIK AMIKOM Purwokerto selalu melakukan penerimaan calon mahasiswa. Data mahasiswa baru tersebut sangat berguna bagi bagian pemasaran sebagai informasi untuk evaluasi kegiatan pemasaran berikutnya. Dengan dibangunnya data warehouse dan aplikasi OLAP dengan menggunakan aplikasi Pentaho Data Integration/Kettle sebagai perangkat ETL dan Pentaho Workbench yang merupakan Online Analytical Processing (OLAP sebagai pengolah database, manajemen di STMIK AMIKOM Purwokerto bisa mengambil beberapa informasi misalnya; banyak jumlah pendaftar per-periode/gelombang, per/asal sekolahnya, per/asal sumber informasi yang diperoleh calon mahasiswa baru, serta tren minat terhadap jurusan yang dipilih oleh calon mahasiswa baru. Data warehouse mampu menganalisis data transaksi, mampu memberikan laporan yang dinamis dan mampu memberikan informasi dalam berbagai dimensi tentang penerimaan mahasiswa baru di STMIK AMIKOM Purwokerto.Kata Kunci: Data Warehouse, OLAP, Pentaho, Penerimaan Calon Mahasiswa.

  6. Optical linear algebra processors - Architectures and algorithms

    Science.gov (United States)

    Casasent, David

    1986-01-01

    Attention is given to the component design and optical configuration features of a generic optical linear algebra processor (OLAP) architecture, as well as the large number of OLAP architectures, number representations, algorithms and applications encountered in current literature. Number-representation issues associated with bipolar and complex-valued data representations, high-accuracy (including floating point) performance, and the base or radix to be employed, are discussed, together with case studies on a space-integrating frequency-multiplexed architecture and a hybrid space-integrating and time-integrating multichannel architecture.

  7. Optical Array Processor: Laboratory Results

    Science.gov (United States)

    Casasent, David; Jackson, James; Vaerewyck, Gerard

    1987-01-01

    A Space Integrating (SI) Optical Linear Algebra Processor (OLAP) is described and laboratory results on its performance in several practical engineering problems are presented. The applications include its use in the solution of a nonlinear matrix equation for optimal control and a parabolic Partial Differential Equation (PDE), the transient diffusion equation with two spatial variables. Frequency-multiplexed, analog and high accuracy non-base-two data encoding are used and discussed. A multi-processor OLAP architecture is described and partitioning and data flow issues are addressed.

  8. Development of a medical informatics data warehouse.

    Science.gov (United States)

    Wu, Cai

    2006-01-01

    This project built a medical informatics data warehouse (MedInfo DDW) in an Oracle database to analyze medical information which has been collected through Baylor Family Medicine Clinic (FCM) Logician application. The MedInfo DDW used Star Schema with dimensional model, FCM database as operational data store (ODS); the data from on-line transaction processing (OLTP) were extracted and transferred to a knowledge based data warehouse through SQLLoad, and the patient information was analyzed by using on-line analytic processing (OLAP) in Crystal Report.

  9. Fatigue-related crashes involving express buses in Malaysia: will the proposed policy of banning the early-hour operation reduce fatigue-related crashes and benefit overall road safety?

    Science.gov (United States)

    Mohamed, Norlen; Mohd-Yusoff, Mohammad-Fadhli; Othman, Ilhamah; Zulkipli, Zarir-Hafiz; Osman, Mohd Rasid; Voon, Wong Shaw

    2012-03-01

    Fatigue-related crashes have long been the topic of discussion and study worldwide. The relationship between fatigue-related crashes and time of day is well documented. In Malaysia, the possibility of banning express buses from operating during the early-hours of the morning has emerged as an important consideration for passenger safety. This paper highlights the findings of an impact assessment study. The study was conducted to determine all possible impacts prior to the government making any decision on the proposed banning. This study is an example of a simple and inexpensive approach that may influence future policy-making process. The impact assessment comprised two major steps. The first step involved profiling existing operation scenarios, gathering information on crashes involving public express buses and stakeholders' views. The second step involved a qualitative impact assessment analysis using all information gathered during the profiling stage to describe the possible impacts. Based on the assessment, the move to ban early-hour operations could possibly result in further negative impacts on the overall road safety agenda. These negative impacts may occur if the fundamental issues, such as driving and working hours, and the need for rest and sleep facilities for drivers, are not addressed. In addition, a safer and more accessible public transportation system as an alternative for those who choose to travel at night would be required. The proposed banning of early-hour operations is also not a feasible solution for sustainability of express bus operations in Malaysia, especially for those operating long journeys. The paper concludes by highlighting the need to design a more holistic approach for preventing fatigue-related crashes involving express buses in Malaysia. Copyright © 2011 Elsevier Ltd. All rights reserved.

  10. "Real-Time Optical Laboratory Linear Algebra Solution Of Partial Differential Equations"

    Science.gov (United States)

    Casasent, David; Jackson, James

    1986-03-01

    A Space Integrating (SI) Optical Linear Algebra Processor (OLAP) employing space and frequency-multiplexing, new partitioning and data flow, and achieving high accuracy performance with a non base-2 number system is described. Laboratory data on the performance of this system and the solution of parabolic Partial Differential Equations (PDEs) is provided. A multi-processor OLAP system is also described for the first time. It use in the solution of multiple banded matrices that frequently arise is then discussed. The utility and flexibility of this processor compared to digital systolic architectures should be apparent.

  11. Application of optical processing to adaptive phased array radar

    Science.gov (United States)

    Carroll, C. W.; Vijaya Kumar, B. V. K.

    1988-01-01

    The results of the investigation of the applicability of optical processing to Adaptive Phased Array Radar (APAR) data processing will be summarized. Subjects that are covered include: (1) new iterative Fourier transform based technique to determine the array antenna weight vector such that the resulting antenna pattern has nulls at desired locations; (2) obtaining the solution of the optimal Wiener weight vector by both iterative and direct methods on two laboratory Optical Linear Algebra Processing (OLAP) systems; and (3) an investigation of the effects of errors present in OLAP systems on the solution vectors.

  12. Analysis of post-operative changes in serum protein expression profiles from colorectal cancer patients by MALDI-TOF mass spectrometry: a pilot methodological study

    Directory of Open Access Journals (Sweden)

    Marsh Simon

    2010-04-01

    Full Text Available Abstract Background Mass spectrometry-based protein expression profiling of blood sera can be used to discriminate colorectal cancer (CRC patients from unaffected individuals. In a pilot methodological study, we have evaluated the changes in protein expression profiles of sera from CRC patients that occur following surgery to establish the potential of this approach for monitoring post-surgical response and possible early prediction of disease recurrence. Methods In this initial pilot study, serum specimens from 11 cancer patients taken immediately prior to surgery and at approximately 6 weeks following surgery were analysed alongside 10 normal control sera by matrix-assisted laser desorption ionisation time of-flight-mass spectrometry (MALDI-TOF MS. Using a two-sided t-test the top 20 ranked protein peaks that discriminate normal from pre-operative sera were identified. These were used to classify post-operative sera by hierarchical clustering analysis (Spearman's Rank correlation and, as an independent 'test' dataset, by k-nearest neighbour and weighted voting supervised learning algorithms. Results Hierarchical cluster analysis classified post-operative sera from all six early Dukes' stage (A and B patients as normal. The remaining five post-operative sera from more advanced Dukes' stages (C1 and C2 were classified as cancer. Analysis by supervised learning algorithms similarly grouped all advanced Dukes' stages as cancer, with four of the six post-operative sera from early Dukes' stages being classified as normal (P = 0.045; Fisher's exact test. Conclusions The results of this pilot methodological study illustrate the proof-of-concept of using protein expression profiling of post-surgical blood sera from individual patients to monitor disease course. Further validation on a larger patient cohort and using an independent post-operative sera dataset would be required to evaluate the potential clinical relevance of this approach. Prospective

  13. Operator bosonization on Riemann surfaces: new vertex operators

    International Nuclear Information System (INIS)

    Semikhatov, A.M.

    1989-01-01

    A new formalism is proposed for the construction of an operator theory of generalized ghost systems (bc theories of spin J) on Riemann surfaces (loop diagrams of the theory of closed strings). The operators of the bc system are expressed in terms of operators of the bosonic conformal theory on a Riemann surface. In contrast to the standard bosonization formulas, which have meaning only locally, operator Baker-Akhiezer functions, which are well defined globally on a Riemann surface of arbitrary genus, are introduced. The operator algebra of the Baker-Akhiezer functions generates explicitly the algebraic-geometric τ function and correlation functions of bc systems on Riemann surfaces

  14. Equilibrium relations and bipolar cognitive mapping for online analytical processing with applications in international relations and strategic decision support.

    Science.gov (United States)

    Zhang, Wen-Ran

    2003-01-01

    Bipolar logic, bipolar sets, and equilibrium relations are proposed for bipolar cognitive mapping and visualization in online analytical processing (OLAP) and online analytical mining (OLAM). As cognitive models, cognitive maps (CMs) hold great potential for clustering and visualization. Due to the lack of a formal mathematical basis, however, CM-based OLAP and OLAM have not gained popularity. Compared with existing approaches, bipolar cognitive mapping has a number of advantages. First, bipolar CMs are formal logical models as well as cognitive models. Second, equilibrium relations (with polarized reflexivity, symmetry, and transitivity), as bipolar generalizations and fusions of equivalence relations, provide a theoretical basis for bipolar visualization and coordination. Third, an equilibrium relation or CM induces bipolar partitions that distinguish disjoint coalition subsets not involved in any conflict, disjoint coalition subsets involved in a conflict, disjoint conflict subsets, and disjoint harmony subsets. Finally, equilibrium energy analysis leads to harmony and stability measures for strategic decision and multiagent coordination. Thus, this work bridges a gap for CM-based clustering and visualization in OLAP and OLAM. Basic ideas are illustrated with example CMs in international relations.

  15. Repressor-mediated tissue-specific gene expression in plants

    Science.gov (United States)

    Meagher, Richard B [Athens, GA; Balish, Rebecca S [Oxford, OH; Tehryung, Kim [Athens, GA; McKinney, Elizabeth C [Athens, GA

    2009-02-17

    Plant tissue specific gene expression by way of repressor-operator complexes, has enabled outcomes including, without limitation, male sterility and engineered plants having root-specific gene expression of relevant proteins to clean environmental pollutants from soil and water. A mercury hyperaccumulation strategy requires that mercuric ion reductase coding sequence is strongly expressed. The actin promoter vector, A2pot, engineered to contain bacterial lac operator sequences, directed strong expression in all plant vegetative organs and tissues. In contrast, the expression from the A2pot construct was restricted primarily to root tissues when a modified bacterial repressor (LacIn) was coexpressed from the light-regulated rubisco small subunit promoter in above-ground tissues. Also provided are analogous repressor operator complexes for selective expression in other plant tissues, for example, to produce male sterile plants.

  16. Operator dependent choice of prostate cancer biopsy has limited impact on a gene signature analysis for the highly expressed genes IGFBP3 and F3 in prostate cancer epithelial cells.

    Directory of Open Access Journals (Sweden)

    Zhuochun Peng

    Full Text Available BACKGROUND: Predicting the prognosis of prostate cancer disease through gene expression analysis is receiving increasing interest. In many cases, such analyses are based on formalin-fixed, paraffin embedded (FFPE core needle biopsy material on which Gleason grading for diagnosis has been conducted. Since each patient typically has multiple biopsy samples, and since Gleason grading is an operator dependent procedure known to be difficult, the impact of the operator's choice of biopsy was evaluated. METHODS: Multiple biopsy samples from 43 patients were evaluated using a previously reported gene signature of IGFBP3, F3 and VGLL3 with potential prognostic value in estimating overall survival at diagnosis of prostate cancer. A four multiplex one-step qRT-PCR test kit, designed and optimized for measuring the signature in FFPE core needle biopsy samples was used. Concordance of gene expression levels between primary and secondary Gleason tumor patterns, as well as benign tissue specimens, was analyzed. RESULTS: The gene expression levels of IGFBP3 and F3 in prostate cancer epithelial cell-containing tissue representing the primary and secondary Gleason patterns were high and consistent, while the low expressed VGLL3 showed more variation in its expression levels. CONCLUSION: The assessment of IGFBP3 and F3 gene expression levels in prostate cancer tissue is independent of Gleason patterns, meaning that the impact of operator's choice of biopsy is low.

  17. A survey of open source tools for business intelligence

    DEFF Research Database (Denmark)

    Thomsen, Christian; Pedersen, Torben Bach

    2005-01-01

    The industrial use of open source Business Intelligence (BI) tools is not yet common. It is therefore of interest to explore which possibilities are available for open source BI and compare the tools. In this survey paper, we consider the capabilities of a number of open source tools for BI....... In the paper, we consider three Extract-Transform-Load (ETL) tools, three On-Line Analytical Processing (OLAP) servers, two OLAP clients, and four database management systems (DBMSs). Further, we describe the licenses that the products are released under. It is argued that the ETL tools are still not very...

  18. Operator continued fraction and bound states

    International Nuclear Information System (INIS)

    Pindor, M.

    1984-01-01

    The effective Hamiltonian of the model space perturbation theory (multilevel Rayleigh-Schroedinger theory) is expressed as an operator continued fraction. In the case of a nondegenerate model space the expression becomes an operator branched continued fraction. The method is applied to the harmonic oscillator with the kinetic energy treated as the perturbation and to the anharmonic oscillator

  19. Post operative infection and sepsis in humans is associated with deficient gene expression of gammac cytokines and their apoptosis mediators.

    LENUS (Irish Health Repository)

    White, Mary

    2011-06-28

    Abstract Introduction Lymphocyte homeostasis is dependent on the γc cytokines. We hypothesised that sepsis in humans is associated with differential gene expression of the γc cytokines and their associated apoptosis mediators. Methods The study population consisted of a total of 60 patients with severe sepsis, 15 with gram negative bacteraemia, 10 healthy controls and 60 patients undergoing elective lung resection surgery. Pneumonia was diagnosed by CDC NNIC criteria. Gene expression in peripheral blood leukocytes (PBLs) of interleukin (IL)-2, 7, 15 and interferon (IFN)-γ, Bax, Bim, Bcl-2 was determined by qRT-PCR and IL-2 and IL-7 serum protein levels by ELISA. Gene expression of IL-2, 7 and IFN-γ was measured in peripheral blood leukocytes (PBL), cultured in the presence of lipopolysacharide (LPS) and CD3 binding antibody (CD3ab) Results IL-2 gene expression was lower in the bacteraemia group compared with controls, and lower still in the sepsis group (P < 0.0001). IL-7 gene expression was similar in controls and bacteraemia, but lower in sepsis (P < 0.0001). IL-15 gene expression was similar in the three groups. Bcl-2 gene expression was less (P < 0.0001) and Bim gene expression was greater (P = 0.0003) in severe sepsis compared to bacteraemic and healthy controls. Bax gene expression was similar in the three groups. In lung resection surgery patients, post-operative pneumonia was associated with a perioperative decrease in IL-2 mRNA (P < 0.0001) and IL-7 mRNA (P = 0.003). IL-2 protein levels were reduced in sepsis and bacteraemia compared to controls (P = 0.02) but similar in pneumonia and non-pneumonia groups. IL-7 protein levels were similar in all groups. In cultured PBLs, IFN-γ gene expression was decreased in response to LPS and increased in response to CD3ab with sepsis: IL-7 gene expression increased in response to LPS in controls and to CD3ab with sepsis; Bcl-2 gene expression decreased in response to combined CD3ab and IL-2 with sepsis

  20. Linear Time Logics around PSL: Complexity, Expressiveness, and a little bit of Succinctness

    DEFF Research Database (Denmark)

    Lange, Martin

    2007-01-01

    We consider linear time temporal logic enriched with semi-extended regular expressions through various operators that have been proposed in the literature, in particular in Accelera's Property Specification Language. We obtain results about the expressive power of fragments of this logic when...... restricted to certain operators only: basically, all operators alone suffice for expressive completeness w.r.t.\\ omega-regular expressions, just the closure operator is too weak. We also obtain complexity results. Again, almost all operators alone suffice for EXPSPACE-completeness, just the closure operator...

  1. Computer algebra and operators

    Science.gov (United States)

    Fateman, Richard; Grossman, Robert

    1989-01-01

    The symbolic computation of operator expansions is discussed. Some of the capabilities that prove useful when performing computer algebra computations involving operators are considered. These capabilities may be broadly divided into three areas: the algebraic manipulation of expressions from the algebra generated by operators; the algebraic manipulation of the actions of the operators upon other mathematical objects; and the development of appropriate normal forms and simplification algorithms for operators and their actions. Brief descriptions are given of the computer algebra computations that arise when working with various operators and their actions.

  2. An Improved Surface Simplification Method for Facial Expression Animation Based on Homogeneous Coordinate Transformation Matrix and Maximum Shape Operator

    Directory of Open Access Journals (Sweden)

    Juin-Ling Tseng

    2016-01-01

    Full Text Available Facial animation is one of the most popular 3D animation topics researched in recent years. However, when using facial animation, a 3D facial animation model has to be stored. This 3D facial animation model requires many triangles to accurately describe and demonstrate facial expression animation because the face often presents a number of different expressions. Consequently, the costs associated with facial animation have increased rapidly. In an effort to reduce storage costs, researchers have sought to simplify 3D animation models using techniques such as Deformation Sensitive Decimation and Feature Edge Quadric. The studies conducted have examined the problems in the homogeneity of the local coordinate system between different expression models and in the retainment of simplified model characteristics. This paper proposes a method that applies Homogeneous Coordinate Transformation Matrix to solve the problem of homogeneity of the local coordinate system and Maximum Shape Operator to detect shape changes in facial animation so as to properly preserve the features of facial expressions. Further, root mean square error and perceived quality error are used to compare the errors generated by different simplification methods in experiments. Experimental results show that, compared with Deformation Sensitive Decimation and Feature Edge Quadric, our method can not only reduce the errors caused by simplification of facial animation, but also retain more facial features.

  3. Structural properties of recursively partitionable graphs with connectivity 2

    DEFF Research Database (Denmark)

    Baudon, Olivier; Bensmail, Julien; Foucaud, Florent

    2017-01-01

    , namely the ones of being online arbitrarily partitionable and recursively arbitrarily partitionable (OL-AP and R-AP for short, respectively), in which the subgraphs induced by a partition of G must not only be con-nected but also ful_l additional conditions. In this paper, we point out some structural...... properties of OL-AP and R-AP graphs with connectivity 2. In particular, we show that deleting a cut pair of these graphs results in a graph with a bounded number of components, some of whom have a small number of vertices. We obtain these results by studying a simple class of 2-connected graphs called...

  4. PRMS Data Warehousing Prototype

    Science.gov (United States)

    Guruvadoo, Eranna K.

    2002-01-01

    Project and Resource Management System (PRMS) is a web-based, mid-level management tool developed at KSC to provide a unified enterprise framework for Project and Mission management. The addition of a data warehouse as a strategic component to the PRMS is investigated through the analysis, design and implementation processes of a data warehouse prototype. As a proof of concept, a demonstration of the prototype with its OLAP's technology for multidimensional data analysis is made. The results of the data analysis and the design constraints are discussed. The prototype can be used to motivate interest and support for an operational data warehouse.

  5. Major Naval Operations

    Science.gov (United States)

    2008-09-01

    operation were to take Turkey out of the war, open a direct link with the Entente’s embattled ally in Russia, force the Germans to shift troops from the...ing craft, while four combat craft (two tor- pedo craft and two light patrol craft) were captured in Port of Adabia. 5. Hartmut Zehrer, ed., Der...mission as a whole is accomplished. At the operational level, the intent is an expression of the commander’s operational vision. It provides a link

  6. Compton Operator in Quantum Electrodynamics

    International Nuclear Information System (INIS)

    Garcia, Hector Luna; Garcia, Luz Maria

    2015-01-01

    In the frame in the quantum electrodynamics exist four basic operators; the electron self-energy, vacuum polarization, vertex correction, and the Compton operator. The first three operators are very important by its relation with renormalized and Ward identity. However, the Compton operator has equal importance, but without divergence, and little attention has been given it. We have calculated the Compton operator and obtained the closed expression for it in the frame of dimensionally continuous integration and hypergeometric functions

  7. RANCANG BANGUN SISTEM INFORMASI INVENTORI MENGGUNAKAN METODE ASSOCIATION RULES DI CV. DAMAR LANGIT

    Directory of Open Access Journals (Sweden)

    Zainul Fanani

    2012-03-01

    Kata Kunci : Sistem informasi, Inventori, Sistem Pendukung Keputusan (Decisition Support System, Association Rule, Data Mining, OLAP (Online Analitic Processing, Algoritma Apriori, Support, Confidence, Lift Rasio.

  8. Operational Plan Ontology Model for Interconnection and Interoperability

    Science.gov (United States)

    Long, F.; Sun, Y. K.; Shi, H. Q.

    2017-03-01

    Aiming at the assistant decision-making system’s bottleneck of processing the operational plan data and information, this paper starts from the analysis of the problem of traditional expression and the technical advantage of ontology, and then it defines the elements of the operational plan ontology model and determines the basis of construction. Later, it builds up a semi-knowledge-level operational plan ontology model. Finally, it probes into the operational plan expression based on the operational plan ontology model and the usage of the application software. Thus, this paper has the theoretical significance and application value in the improvement of interconnection and interoperability of the operational plan among assistant decision-making systems.

  9. SOLAP technology: Merging business intelligence with geospatial technology for interactive spatio-temporal exploration and analysis of data

    Science.gov (United States)

    Rivest, Sonia; Bédard, Yvan; Proulx, Marie-Josée; Nadeau, Martin; Hubert, Frederic; Pastor, Julien

    To support their analytical processes, today's organizations deploy data warehouses and client tools such as OLAP (On-Line Analytical Processing) to access, visualize, and analyze their integrated, aggregated and summarized data. Since a large part of these data have a spatial component, better client tools are required to take full advantage of the geometry of the spatial phenomena or objects being analyzed. With this regard, Spatial OLAP (SOLAP) technology offers promising possibilities. A SOLAP tool can be defined as "a type of software that allows rapid and easy navigation within spatial databases and that offers many levels of information granularity, many themes, many epochs and many display modes synchronized or not: maps, tables and diagrams" [Bédard, Y., Proulx, M.J., Rivest, S., 2005. Enrichissement du OLAP pour l'analyse géographique: exemples de réalisation et différentes possibilités technologiques. In: Bentayeb, F., Boussaid, O., Darmont, J., Rabaseda, S. (Eds.), Entrepôts de Données et Analyse en ligne, RNTI B_1. Paris: Cépaduès, pp. 1-20]. SOLAP tools offer a new user interface and are meant to be client applications sitting on top of multi-scale spatial data warehouses or datacubes. As they are based on the multidimensional paradigm, they facilitate the interactive spatio-temporal exploration of data. The purpose of this paper is to discuss how SOLAP concepts support spatio-temporal exploration of data and then to present the geovisualization, interactivity, and animation features of the SOLAP software developed by our research group. This paper first reviews the general concepts behind OLAP and SOLAP systems. This is followed by a discussion of how these SOLAP concepts support spatio-temporal exploration of data. In the subsequent section, SOLAP software is introduced along with features that enable geovisualization, interactivity and animation.

  10. Favorable prognosis of operable non-small cell lung cancer (NSCLC) patients harboring an increased expression of tumor endothelial markers (TEMs).

    Science.gov (United States)

    Pircher, Andreas; Fiegl, Michael; Untergasser, Gerold; Heidegger, Isabel; Medinger, Michael; Kern, Johann; Hilbe, Wolfgang

    2013-08-01

    Genome analyses of endothelial cells identified genes specifically expressed by tumor endothelial cells, called tumor endothelial markers (TEMs). Currently there are no data available concerning the role of TEMs in non-small cell lung cancer (NSCLC). Therefore, the aim of this study was to investigate the role of TEMs in NSCLC in vitro and in vivo. First we evaluated the expression of various TEMs (Robo4, Clec14 and ECSCR) by qRT-PCR and Western blot analyses in three NSCLC cell lines (A549, Calu1, Colo699) and compared them to human umbilical vein endothelial cells (HUVECs), endothelial colony forming cells (ECFCs) and human bronchial epithelial cells (HBEpCs). Next the expression of TEMs was measured in resected tumor tissue of NSCLC patients (n = 63) by qRT-PCR and compared to adjacent non-cancerous lung tissue (n = 52). Further, immunohistochemical analysis of Robo4 expression in tumor tissue (n = 33) and adjacent non-cancerous tissue (n = 27) was performed. We found that NSCLC cell lines and HBEpC did not express TEMs on the mRNA level compared to HUVECs (p = 0.001). In the contrary, a significant up-regulation of Robo4 and Clec14 was found in tumor samples (Robo4 p = 0.03, Clec14 p = 0.002). Both facts clearly indicate that these proteins are allocated to the tumor stromal department. Correlation with clinical data showed that increased TEM expression correlated with prolonged overall survival of operated NSCLC patients (Robo4 high 120.5 vs. Robo4 low 47.6 months, Clec14 high 108.1 vs. Clec14 low 54.5 months and ECSCR high 120.5 vs. ECSCR low 42.2 months). In summary, we found that TEMs are overexpressed in NSCLC stromal tissue and that an increased TEM expression correlated with an increased overall survival in early stage NSCLC. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  11. PERANGKAT LUNAK ANTAR MUKA GRAFIS SCHEMA DAN CUBE EDITOR MS ANALYSIS SERVICE BERBASIS WEB

    Directory of Open Access Journals (Sweden)

    Faizal Johan

    2007-01-01

    Full Text Available Aplikasi Web telah menjadi bagian yang tidak terpisahkan lagi dalam kehidupan sehari-hari. Seiring dengan meningkatnya teknologi internet membuat seorang administrator tidak perlu berada didepan komputer server untuk dapat melakukan pekerjaan administratif seperti membuat analisis proses secara online dari sebuah schema database untuk dibuat schema cube (data warehousing dan melakukan perubahan pada schema yang sudah dibuat.Untuk dapat melakukan hal tersebut SQL Server 7.0 maupun SQL Server 2000 telah menyediakan fasilitas pengaksesan tabel dimensi, cube, relasi dan koneksi database dalam Analysis Manager menggunakan DSO (Decision Support Object library component MS OLAP. Dengan adanya DSO connection, seorang administrator dapat memanipulasi schema, tabel, cube, dimension, relasi suatu schema cube dari database SQL Server secara langsung dengan menggunakan bahasa pemrograman yang mendukung, seperti MS Visual Basic, VBScript, MS Visual C++, MS.Net. Dalam penelitian ini dibuat aplikasi berbasis web yang merupakan tahap awal dari OLAP (Online Analytical Processing suatu schema database dengan menggunakan SQL Analysis Service, Analysis Manager yang memungkinkan seorang administrator database untuk dapat melakukan pekerjaan administratif khususnya membuat schema dan cube (fact table dari database yang dianalisis, membuat dan mengedit dimensi, dimana saja tanpa harus berada di komputer server. Kata Kunci : DSO, Cube, Measure,GUI, dimensi, fact table, ADO MD, SQL DMO, OLAP.

  12. Natural language processing using online analytic processing for assessing recommendations in radiology reports.

    Science.gov (United States)

    Dang, Pragya A; Kalra, Mannudeep K; Blake, Michael A; Schultz, Thomas J; Stout, Markus; Lemay, Paul R; Freshman, David J; Halpern, Elkan F; Dreyer, Keith J

    2008-03-01

    The study purpose was to describe the use of natural language processing (NLP) and online analytic processing (OLAP) for assessing patterns in recommendations in unstructured radiology reports on the basis of patient and imaging characteristics, such as age, gender, referring physicians, radiology subspecialty, modality, indications, diseases, and patient status (inpatient vs outpatient). A database of 4,279,179 radiology reports from a single tertiary health care center during a 10-year period (1995-2004) was created. The database includes reports of computed tomography, magnetic resonance imaging, fluoroscopy, nuclear medicine, ultrasound, radiography, mammography, angiography, special procedures, and unclassified imaging tests with patient demographics. A clinical data mining and analysis NLP program (Leximer, Nuance Inc, Burlington, Massachusetts) in conjunction with OLAP was used for classifying reports into those with recommendations (I(REC)) and without recommendations (N(REC)) for imaging and determining I(REC) rates for different patient age groups, gender, imaging modalities, indications, diseases, subspecialties, and referring physicians. In addition, temporal trends for I(REC) were also determined. There was a significant difference in the I(REC) rates in different age groups, varying between 4.8% (10-19 years) and 9.5% (>70 years) (P OLAP revealed considerable differences between recommendation trends for different imaging modalities and other patient and imaging characteristics.

  13. Expressing Inter-task Dependencies between Parallel Stencil Operations

    DEFF Research Database (Denmark)

    Larsen, Per; Karlsson, Sven; Madsen, Jan

    2010-01-01

    ) captures an upper bound on the number of dependencies between successive stencil operations and ii) instructs the compiler to generate code which ensures that the bound holds for each execution of the program. The impact of our proposal is evaluated using a micro-benchmark and two soft real-time embedded...

  14. Dimensionless Numbers Expressed in Terms of Common CVD Process Parameters

    Science.gov (United States)

    Kuczmarski, Maria A.

    1999-01-01

    A variety of dimensionless numbers related to momentum and heat transfer are useful in Chemical Vapor Deposition (CVD) analysis. These numbers are not traditionally calculated by directly using reactor operating parameters, such as temperature and pressure. In this paper, these numbers have been expressed in a form that explicitly shows their dependence upon the carrier gas, reactor geometry, and reactor operation conditions. These expressions were derived for both monatomic and diatomic gases using estimation techniques for viscosity, thermal conductivity, and heat capacity. Values calculated from these expressions compared well to previously published values. These expressions provide a relatively quick method for predicting changes in the flow patterns resulting from changes in the reactor operating conditions.

  15. Commutation relations for functions of operators

    International Nuclear Information System (INIS)

    Transtrum, Mark K.; Van Huele, Jean-Francois S.

    2005-01-01

    We derive an expression for the commutator of functions of operators with constant commutations relations in terms of the partial derivatives of these functions. This result extends the well-known commutation relation between one operator and a function of another operator. We discuss the range of applicability of the formula with examples in quantum mechanics

  16. Big Data

    OpenAIRE

    Bútora, Matúš

    2017-01-01

    Cieľom bakalárskej práca je popísať problematiku Big Data a agregačné operácie OLAP pre podporu rozhodovania, ktoré sú na ne aplikované pomocou technológie Apache Hadoop. Prevažná časť práce je venovaná popisu práve tejto technológie. Posledná kapitola sa zaoberá spôsobom aplikovania agregačných operácií a problematikou ich realizácie. Nasleduje celkové zhodnotenie práce a možnosti využitia výsledného systému do budúcna. The aim of the bachelor thesis is to describe the Big Data issue and ...

  17. Gene expression

    International Nuclear Information System (INIS)

    Hildebrand, C.E.; Crawford, B.D.; Walters, R.A.; Enger, M.D.

    1983-01-01

    We prepared probes for isolating functional pieces of the metallothionein locus. The probes enabled a variety of experiments, eventually revealing two mechanisms for metallothionein gene expression, the order of the DNA coding units at the locus, and the location of the gene site in its chromosome. Once the switch regulating metallothionein synthesis was located, it could be joined by recombinant DNA methods to other, unrelated genes, then reintroduced into cells by gene-transfer techniques. The expression of these recombinant genes could then be induced by exposing the cells to Zn 2+ or Cd 2+ . We would thus take advantage of the clearly defined switching properties of the metallothionein gene to manipulate the expression of other, perhaps normally constitutive, genes. Already, despite an incomplete understanding of how the regulatory switch of the metallothionein locus operates, such experiments have been performed successfully

  18. Pre-Aggregation with Probability Distributions

    DEFF Research Database (Denmark)

    Timko, Igor; Dyreson, Curtis E.; Pedersen, Torben Bach

    2006-01-01

    Motivated by the increasing need to analyze complex, uncertain multidimensional data this paper proposes probabilistic OLAP queries that are computed using probability distributions rather than atomic values. The paper describes how to create probability distributions from base data, and how...... the distributions can be subsequently used in pre-aggregation. Since the probability distributions can become large, we show how to achieve good time and space efficiency by approximating the distributions. We present the results of several experiments that demonstrate the effectiveness of our methods. The work...... is motivated with a real-world case study, based on our collaboration with a leading Danish vendor of location-based services. This paper is the first to consider the approximate processing of probabilistic OLAP queries over probability distributions....

  19. VMEXT: A Visualization Tool for Mathematical Expression Trees

    OpenAIRE

    Schubotz, Moritz; Meuschke, Norman; Hepp, Thomas; Cohl, Howard S.; Gipp, Bela

    2017-01-01

    Mathematical expressions can be represented as a tree consisting of terminal symbols, such as identifiers or numbers (leaf nodes), and functions or operators (non-leaf nodes). Expression trees are an important mechanism for storing and processing mathematical expressions as well as the most frequently used visualization of the structure of mathematical expressions. Typically, researchers and practitioners manually visualize expression trees using general-purpose tools. This approach is labori...

  20. The Effect of Dexmedetomidine on Cognitive Function and Protein Expression of Aβ, p-Tau, and PSD95 after Extracorporeal Circulation Operation in Aged Rats

    Directory of Open Access Journals (Sweden)

    Ying Zhang

    2018-01-01

    Full Text Available Postoperative cognitive dysfunction (POCD is a kind of serious neurologic complications and dexmedetomidine has a certain effect on POCD. However, functional mechanism of dexmedetomidine on POCD still remains unclear, so the research mainly studied the effect of dexmedetomidine on cognitive function and protein expression in hippocampus and prefrontal cortex cerebrospinal fluid after extracorporeal circulation operation in aged rats. We Found that, compared with POCD group, the cognitive function was improved in POCD + Dex group. We speculate that dexmedetomidine could improve the cognitive function after extracorporeal circulation operation in aged rats and Aβ, p-Tau, and PSD95 protein might have contributed to this favorable outcome.

  1. Accuracy Limitations in Optical Linear Algebra Processors

    Science.gov (United States)

    Batsell, Stephen Gordon

    1990-01-01

    One of the limiting factors in applying optical linear algebra processors (OLAPs) to real-world problems has been the poor achievable accuracy of these processors. Little previous research has been done on determining noise sources from a systems perspective which would include noise generated in the multiplication and addition operations, noise from spatial variations across arrays, and from crosstalk. In this dissertation, we propose a second-order statistical model for an OLAP which incorporates all these system noise sources. We now apply this knowledge to determining upper and lower bounds on the achievable accuracy. This is accomplished by first translating the standard definition of accuracy used in electronic digital processors to analog optical processors. We then employ our second-order statistical model. Having determined a general accuracy equation, we consider limiting cases such as for ideal and noisy components. From the ideal case, we find the fundamental limitations on improving analog processor accuracy. From the noisy case, we determine the practical limitations based on both device and system noise sources. These bounds allow system trade-offs to be made both in the choice of architecture and in individual components in such a way as to maximize the accuracy of the processor. Finally, by determining the fundamental limitations, we show the system engineer when the accuracy desired can be achieved from hardware or architecture improvements and when it must come from signal pre-processing and/or post-processing techniques.

  2. Expression of vascular endothelial growth factor in Juvenile Angiofibroma.

    Science.gov (United States)

    Hota, Ashutosh; Sarkar, Chitra; Gupta, Siddhartha Datta; Kumar, Rakesh; Bhalla, Ashu Seith; Thakar, Alok

    2015-06-01

    To examine Juvenile Angiofibroma (JA) tissue for expression of vascular endothelial growth factor (VEGF), and to explore its relationship with puberty status, stage, recurrence and the intraoperative blood loss. Retrospective cohort study of 36 histologically proven cases of JA. Minimum follow up period was 3 years. VEGF expression on tumor cells assessed by immunohistochemistry and graded on two criteria--percentage of cells expressing positivity and the intensity of positivity. These two parameters assessed for impact on puberty status, stage, recurrence, and blood loss. VEGF expression noted on the tumor endothelial cells in 36/36, and on the tumor stromal cells in 34/36. The percentage of cells expressing VEGF and the intensity of expression were not significantly related to puberty status, tumor stage, recurrence, or intra-operative blood loss (p values 0.3-1.0). VEGF expression is near universal in JA. Such expression is independent of puberty status and stage, and does not impact on intra operative blood loss and recurrence. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. Methods of expressing and detecting activity of expansin in plant cells

    Energy Technology Data Exchange (ETDEWEB)

    Hood, Elizabeth E.; Yoon, Sangwoong

    2017-10-10

    A method of expressing heterologous expansin in a plant cell is provided where a nucleic acid molecule encoding expansin is introduced into the plant cell and in an embodiment is operably linked to a promoter preferentially expressing in the seed tissue of the plant, and in another embodiment is linked to a promoter preferentially expressing in the embryo tissue of the seed. An embodiment provides the nucleic acid molecule is operably linked to a second nucleic acid molecule that directs expression to the endoplasmic reticulum, vacuole or cell wall. Plants and plant parts expressing expansin are provided. An assay for detection of expansin activity is also provided.

  4. Data mining, mining data : energy consumption modelling

    Energy Technology Data Exchange (ETDEWEB)

    Dessureault, S. [Arizona Univ., Tucson, AZ (United States)

    2007-09-15

    Most modern mining operations are accumulating large amounts of data on production and business processes. Data, however, provides value only if it can be translated into information that appropriate users can utilize. This paper emphasized that a new technological focus should emerge, notably how to concentrate data into information; analyze information sufficiently to become knowledge; and, act on that knowledge. Researchers at the Mining Information Systems and Operations Management (MISOM) laboratory at the University of Arizona have created a method to transform data into action. The data-to-action approach was exercised in the development of an energy consumption model (ECM), in partnership with a major US-based copper mining company, 2 software companies, and the MISOM laboratory. The approach begins by integrating several key data sources using data warehousing techniques, and increasing the existing level of integration and data cleaning. An online analytical processing (OLAP) cube was also created to investigate the data and identify a subset of several million records. Data mining algorithms were applied using the information that was isolated by the OLAP cube. The data mining results showed that traditional cost drivers of energy consumption are poor predictors. A comparison was made between traditional methods of predicting energy consumption and the prediction formed using data mining. Traditionally, in the mines for which data were available, monthly averages of tons and distance are used to predict diesel fuel consumption. However, this article showed that new information technology can be used to incorporate many more variables into the budgeting process, resulting in more accurate predictions. The ECM helped mine planners improve the prediction of energy use through more data integration, measure development, and workflow analysis. 5 refs., 11 figs.

  5. On finding algebraic expressions for genealogical coefficients

    International Nuclear Information System (INIS)

    Kanyauskas, J.M.; Shimonis, V.Ch.; Rudzikas, Z.B.

    1979-01-01

    It has been attempted to obtain analytical expressions for genealogical coefficients with one detached electron in the case of L-S coupling. A method of second quantization and tensorial properties of the quasi-spin operator are applied. It is restricted to the states for the classification of which the seigniority quantum number v is sufficient. Three ways of the acquirement of these expressions are discussed: 1. In the recurrent way wave functions of N and N-1 electrons are built, consequently expressing these functions in terms of the creation-annihilation operators. 2. Recurrent summation with the use of evident, simple genealogical coefficients. 3. Using the ratios, connecting the genealogical coefficients with the normalized multiplier. The data are presented in formulae and discussions. The generalization of the Redmond's formula is obtained and relatively simple algebraic expressions of the genealogical coefficients of the equivalent electron configurations, for the distinction of the recurrent terms of which introduction of the seigniority quantum number v is sufficient, are given

  6. Emerald Express '95: Analysis Report

    National Research Council Canada - National Science Library

    Newett, Sandra

    1996-01-01

    The purpose of Emerald Express was to bring together senior representatives from military, relief, political, and diplomatic communities to address issues that arise during Humanitarian Assistance and Peace Operations (HA/POs...

  7. Pointing and Voicing in Deictic Expressions.

    Science.gov (United States)

    Levelt, Willem J. M.; And Others

    1985-01-01

    Describes a study of how the interdependence of speech and gesture is realized in the course of motor planning and execution. Do the two systems operate interactively or do they operate in a ballistic or independent fashion? Four experiments showed that, for deictic expressions, the ballistic view is very nearly correct. (SED)

  8. Recommending Multidimensional Queries

    Science.gov (United States)

    Giacometti, Arnaud; Marcel, Patrick; Negre, Elsa

    Interactive analysis of datacube, in which a user navigates a cube by launching a sequence of queries is often tedious since the user may have no idea of what the forthcoming query should be in his current analysis. To better support this process we propose in this paper to apply a Collaborative Work approach that leverages former explorations of the cube to recommend OLAP queries. The system that we have developed adapts Approximate String Matching, a technique popular in Information Retrieval, to match the current analysis with the former explorations and help suggesting a query to the user. Our approach has been implemented with the open source Mondrian OLAP server to recommend MDX queries and we have carried out some preliminary experiments that show its efficiency for generating effective query recommendations.

  9. Deterministic automata for extended regular expressions

    Directory of Open Access Journals (Sweden)

    Syzdykov Mirzakhmet

    2017-12-01

    Full Text Available In this work we present the algorithms to produce deterministic finite automaton (DFA for extended operators in regular expressions like intersection, subtraction and complement. The method like “overriding” of the source NFA(NFA not defined with subset construction rules is used. The past work described only the algorithm for AND-operator (or intersection of regular languages; in this paper the construction for the MINUS-operator (and complement is shown.

  10. Hadron matrix elements of quark operators in the relativistic quark model

    Energy Technology Data Exchange (ETDEWEB)

    Bando, Masako; Toya, Mihoko [Kyoto Univ. (Japan). Dept. of Physics; Sugimoto, Hiroshi

    1979-07-01

    General formulae for evaluating matrix elements of two- and four-quark operators sandwiched by one-hadron states are presented on the basis of the relativistic quark model. Observed hadronic quantities are expressed in terms of those matrix elements of two- and four-quark operators. One observes various type of relativistic expression for the matrix elements which in the non-relativistic case reduce to simple expression of the so-called ''the wave function at the origin /sup +/psi(0)/sup +/''.

  11. Operational Aspects of C/C++ Concurrency

    OpenAIRE

    Podkopaev, Anton; Sergey, Ilya; Nanevski, Aleksandar

    2016-01-01

    In this work, we present a family of operational semantics that gradually approximates the realistic program behaviors in the C/C++11 memory model. Each semantics in our framework is built by elaborating and combining two simple ingredients: viewfronts and operation buffers. Viewfronts allow us to express the spatial aspect of thread interaction, i.e., which values a thread can read, while operation buffers enable manipulation with the temporal execution aspect, i.e., determining the order in...

  12. Mining frequent binary expressions

    NARCIS (Netherlands)

    Calders, T.; Paredaens, J.; Kambayashi, Y.; Mohania, M.K.; Tjoa, A.M.

    2000-01-01

    In data mining, searching for frequent patterns is a common basic operation. It forms the basis of many interesting decision support processes. In this paper we present a new type of patterns, binary expressions. Based on the properties of a specified binary test, such as reflexivity, transitivity

  13. Higher-order Zeeman and spin terms in the electron paramagnetic resonance spin Hamiltonian; their description in irreducible form using Cartesian, tesseral spherical tensor and Stevens' operator expressions

    International Nuclear Information System (INIS)

    McGavin, Dennis G; Tennant, W Craighead

    2009-01-01

    In setting up a spin Hamiltonian (SH) to study high-spin Zeeman and high-spin nuclear and/or electronic interactions in electron paramagnetic resonance (EPR) experiments, it is argued that a maximally reduced SH (MRSH) framed in tesseral combinations of spherical tensor operators is necessary. Then, the SH contains only those terms that are necessary and sufficient to describe the particular spin system. The paper proceeds then to obtain interrelationships between the parameters of the MRSH and those of alternative SHs expressed in Cartesian tensor and Stevens operator-equivalent forms. The examples taken, initially, are those of Cartesian and Stevens' expressions for high-spin Zeeman terms of dimension BS 3 and BS 5 . Starting from the well-known decomposition of the general Cartesian tensor of second rank to three irreducible tensors of ranks 0, 1 and 2, the decomposition of Cartesian tensors of ranks 4 and 6 are treated similarly. Next, following a generalization of the tesseral spherical tensor equations, the interrelationships amongst the parameters of the three kinds of expressions, as derived from equivalent SHs, are determined and detailed tables, including all redundancy equations, set out. In each of these cases the lowest symmetry, 1-bar Laue class, is assumed and then examples of relationships for specific higher symmetries derived therefrom. The validity of a spin Hamiltonian containing mixtures of terms from the three expressions is considered in some detail for several specific symmetries, including again the lowest symmetry. Finally, we address the application of some of the relationships derived here to seldom-observed low-symmetry effects in EPR spectra, when high-spin electronic and nuclear interactions are present.

  14. Polarization operator in quantum electrodynamics with a pair-producing external field

    International Nuclear Information System (INIS)

    Barashev, V.P.; Shvartsman, Sh.M.; Shabad, A.E.

    1986-01-01

    Various radiative processes with one-photon initial state are treated in QED with pair-producing external field. It is shown that the probabilities of such processes are expressed in terms of two different polarization operators. For the case of a constant field the polarization operator which is expressed through the so-called causal Green electron function, is calculated. This operator has never been calculated previously. It enters the formula for probability of production of N arbitrary pairs by a photon

  15. Hyponormal differential operators with discrete spectrum

    Directory of Open Access Journals (Sweden)

    Zameddin I. Ismailov

    2010-01-01

    Full Text Available In this work, we first describe all the maximal hyponormal extensions of a minimal operator generated by a linear differential-operator expression of the first-order in the Hilbert space of vector-functions in a finite interval. Next, we investigate the discreteness of the spectrum and the asymptotical behavior of the modules of the eigenvalues for these maximal hyponormal extensions.

  16. ComVisMD - compact visualization of multidimensional data: experimenting with cricket players data

    Science.gov (United States)

    Dandin, Shridhar B.; Ducassé, Mireille

    2018-03-01

    Database information is multidimensional and often displayed in tabular format (row/column display). Presented in aggregated form, multidimensional data can be used to analyze the records or objects. Online Analytical database Processing (OLAP) proposes mechanisms to display multidimensional data in aggregated forms. A choropleth map is a thematic map in which areas are colored in proportion to the measurement of a statistical variable being displayed, such as population density. They are used mostly for compact graphical representation of geographical information. We propose a system, ComVisMD inspired by choropleth map and the OLAP cube to visualize multidimensional data in a compact way. ComVisMD displays multidimensional data like OLAP Cube, where we are mapping an attribute a (first dimension, e.g. year started playing cricket) in vertical direction, object coloring based on b (second dimension, e.g. batting average), mapping varying-size circles based on attribute c (third dimension, e.g. highest score), mapping numbers based on attribute d (fourth dimension, e.g. matches played). We illustrate our approach on cricket players data, namely on two tables Country and Player. They have a large number of rows and columns: 246 rows and 17 columns for players of one country. ComVisMD’s visualization reduces the size of the tabular display by a factor of about 4, allowing users to grasp more information at a time than the bare table display.

  17. Asset management -- Integrated software optimizes production performance

    International Nuclear Information System (INIS)

    Polczer, S.

    1998-01-01

    Developments in data collection and retrieval systems to allow timely cost analysis, financial reporting and production management are discussed. One of the most important new OLAP (on-line analytical processing) products is Energy Warehouse which gathers field information from various sources, allows advanced searches, and generates reports previously unavailable in other conventional financial accounting systems. Another OLAP-based system, the Canadian Upstream Energy System (CUES), was developed by the Oracle Corporation and the Calgary-based Applied Terravision Systems (ATS) Inc. CUES combines Oracle's universal data server software development tools with ATS's upstream financial, land, geotechnical and production applications. ATS also developed a product called IDPMARS (Integrated Daily Production Management Accounting Reporting System). It interfaces with CUES to link working interests, government royalties, administration, facility charges, lifting costs, transportation tooling, and customers by integrating field data collection systems with financial accounting

  18. Asset management -- Integrated software optimizes production performance

    Energy Technology Data Exchange (ETDEWEB)

    Polczer, S.

    1998-10-01

    Developments in data collection and retrieval systems to allow timely cost analysis, financial reporting and production management are discussed. One of the most important new OLAP (on-line analytical processing) products is Energy Warehouse which gathers field information from various sources, allows advanced searches, and generates reports previously unavailable in other conventional financial accounting systems. Another OLAP-based system, the Canadian Upstream Energy System (CUES), was developed by the Oracle Corporation and the Calgary-based Applied Terravision Systems (ATS) Inc. CUES combines Oracle`s universal data server software development tools with ATS`s upstream financial, land, geotechnical and production applications. ATS also developed a product called IDPMARS (Integrated Daily Production Management Accounting Reporting System). It interfaces with CUES to link working interests, government royalties, administration, facility charges, lifting costs, transportation tooling, and customers by integrating field data collection systems with financial accounting.

  19. Extensive co-operation between the Epstein-Barr virus EBNA3 proteins in the manipulation of host gene expression and epigenetic chromatin modification.

    Directory of Open Access Journals (Sweden)

    Robert E White

    2010-11-01

    Full Text Available Epstein-Barr virus (EBV is able to drive the transformation of B-cells, resulting in the generation of lymphoblastoid cell lines (LCLs in vitro. EBV nuclear proteins EBNA3A and EBNA3C are necessary for efficient transformation, while EBNA3B is dispensable. We describe a transcriptome analysis of BL31 cells infected with a series of EBNA3-knockout EBVs, including one deleted for all three EBNA3 genes. Using Affymetrix Exon 1.0 ST microarrays analysed with the MMBGX algorithm, we have identified over 1000 genes whose regulation by EBV requires one of the EBNA3s. Remarkably, a third of the genes identified require more than one EBNA3 for their regulation, predominantly EBNA3C co-operating with either EBNA3B, EBNA3A or both. The microarray was validated by real-time PCR, while ChIP analysis of a selection of co-operatively repressed promoters indicates a role for polycomb group complexes. Targets include genes involved in apoptosis, cell migration and B-cell differentiation, and show a highly significant but subtle alteration in genes involved in mitosis. In order to assess the relevance of the BL31 system to LCLs, we analysed the transcriptome of a set of EBNA3B knockout (3BKO LCLs. Around a third of the genes whose expression level in LCLs was altered in the absence of EBNA3B were also altered in 3BKO-BL31 cell lines.Among these are TERT and TCL1A, implying that EBV-induced changes in the expression of these genes are not required for B-cell transformation. We also identify 26 genes that require both EBNA3A and EBNA3B for their regulation in LCLs. Together, this shows the complexity of the interaction between EBV and its host, whereby multiple EBNA3 proteins co-operate to modulate the behaviour of the host cell.

  20. Developing Students' Mathematical Skills Involving Order of Operations

    Science.gov (United States)

    Ali Rahman, Ernna Sukinnah; Shahrill, Masitah; Abbas, Nor Arifahwati; Tan, Abby

    2017-01-01

    This small-scale action research study examines the students' ability in using their mathematical skills when performing order of operations in numerical expressions. In this study, the "hierarchy-of-operators triangle" by Ameis (2011) was introduced as an alternative BODMAS approach to help students in gaining a better understanding…

  1. LETOS -- A Lightweight Execution Tool for Operational Semantics

    NARCIS (Netherlands)

    Hartel, Pieter H.

    A lightweight tool is proposed to aid in the development of operational semantics. To use LETOS an operational semantics must be expressed in its meta-language, which itself is a superset of Miranda. The LETOS compiler is smaller than comparable tools, yet LETOS is powerful enough to support

  2. Incomplete Intelligence: Is the Information Sharing Environment an Effective Platform?

    Science.gov (United States)

    2012-09-01

    Initiative NYFD New York Fire Department NYPD New York Police Department OLAP On Line Analytics Processing OSINT Open Source Intelligence...Intelligence ( OSINT ), from public websites, media sources, and other unclassified events and reports. Although some of these sources do not have a direct

  3. A Foundation for Spatial Data Warehouses on the Semantic Web


    DEFF Research Database (Denmark)

    Gur, Nurefsan; Pedersen, Torben Bach; Zimaányi, Esteban

    2017-01-01

    Large volumes of geospatial data are being published on the Semantic Web (SW), yielding a need for advanced analysis of such data. However, existing SW technologies only support advanced analytical concepts such as multidimensional (MD) data warehouses and Online Analytical Processing (OLAP) over...

  4. CPU and cache efficient management of memory-resident databases

    NARCIS (Netherlands)

    Pirk, H.; Funke, F.; Grund, M.; Neumann, T.; Leser, U.; Manegold, S.; Kemper, A.; Kersten, M.L.

    2013-01-01

    Memory-Resident Database Management Systems (MRDBMS) have to be optimized for two resources: CPU cycles and memory bandwidth. To optimize for bandwidth in mixed OLTP/OLAP scenarios, the hybrid or Partially Decomposed Storage Model (PDSM) has been proposed. However, in current implementations,

  5. CPU and Cache Efficient Management of Memory-Resident Databases

    NARCIS (Netherlands)

    H. Pirk (Holger); F. Funke; M. Grund; T. Neumann (Thomas); U. Leser; S. Manegold (Stefan); A. Kemper (Alfons); M.L. Kersten (Martin)

    2013-01-01

    htmlabstractMemory-Resident Database Management Systems (MRDBMS) have to be optimized for two resources: CPU cycles and memory bandwidth. To optimize for bandwidth in mixed OLTP/OLAP scenarios, the hybrid or Partially Decomposed Storage Model (PDSM) has been proposed. However, in current

  6. Multidimensi Pada Data Warehouse Dengan Menggunakan Rumus Kombinasi

    OpenAIRE

    Hendric, Spits Warnars Harco Leslie

    2006-01-01

    Multidimensional in data warehouse is a compulsion and become the most important for information delivery, without multidimensional data warehouse is incomplete. Multidimensional give the able to analyze business measurement in many different ways. Multidimensional is also synonymous with online analytical processing (OLAP).

  7. D3.1 State-of-the-art report on data collection and analysis

    DEFF Research Database (Denmark)

    Siksnys, Laurynas; Boehm, Matthias; Pedersen, Torben Bach

    2010-01-01

    management; (4) management of uncertainty in the context of probabilistic databases, OLAP, and data streams; (5) management of multi-version data; (6) efficient tracking of continuous processes; and (7) query optimization based on early aggregation and materialized views. Moreover, relevant existing computer...

  8. SM4MQ: A Semantic Model for Multidimensional Queries

    DEFF Research Database (Denmark)

    Varga, Jovan; Dobrokhotova, Ekaterina; Romero, Oscar

    2017-01-01

    metadata artifacts (e.g., queries) to assist users with the analysis. However, modeling and sharing of most of these artifacts are typically overlooked. Thus, in this paper we focus on the query metadata artifact in the Exploratory OLAP context and propose an RDF-based vocabulary for its representation......, sharing, and reuse on the SW. As OLAP is based on the underlying multidimensional (MD) data model we denote such queries as MD queries and define SM4MQ: A Semantic Model for Multidimensional Queries. Furthermore, we propose a method to automate the exploitation of queries by means of SPARQL. We apply...... the method to a use case of transforming queries from SM4MQ to a vector representation. For the use case, we developed the prototype and performed an evaluation that shows how our approach can significantly ease and support user assistance such as query recommendation....

  9. Analyzing Clickstreams

    DEFF Research Database (Denmark)

    Andersen, Jesper; Giversen, Anders; Jensen, Allan H.

    in modern enterprises. In the data warehousing pproach, selected information is extracted in advance and stored in a repository. This approach is used because of its high performance. However, in many situations a logical (rather than physical) integration of data is preferable. Previous web-based data......On-Line Analytical Processing (OLAP) enables analysts to gain insight into data through fast and interactive access to a variety of possible views on information, organized in a dimensional model. The demand for data integration is rapidly becoming larger as more and more information sources appear....... Extensible Markup Language (XML) is fast becoming the new standard for data representation and exchange on the World Wide Web. The rapid emergence of XML data on the web, e.g., business-to-business (B2B) ecommerce, is making it necessary for OLAP and other data analysis tools to handleXML data as well...

  10. Integrating GIS components with knowledge discovery technology for environmental health decision support.

    Science.gov (United States)

    Bédard, Yvan; Gosselin, Pierre; Rivest, Sonia; Proulx, Marie-Josée; Nadeau, Martin; Lebel, Germain; Gagnon, Marie-France

    2003-04-01

    This paper presents a new category of decision-support tools that builds on today's Geographic Information Systems (GIS) and On-Line Analytical Processing (OLAP) technologies to facilitate Geographic Knowledge Discovery (GKD). This new category, named Spatial OLAP (SOLAP), has been an R&D topic for about 5 years in a few university labs and is now being implemented by early adopters in different fields, including public health where it provides numerous advantages. In this paper, we present an example of a SOLAP application in the field of environmental health: the ICEM-SE project. After having presented this example, we describe the design of this system and explain how it provides fast and easy access to the detailed and aggregated data that are needed for GKD and decision-making in public health. The SOLAP concept is also described and a comparison is made with traditional GIS applications.

  11. Design and implementation of fishery rescue data mart system

    Science.gov (United States)

    Pan, Jun; Huang, Haiguang; Liu, Yousong

    A novel data mart based system for fishery rescue field was designed and implemented. The system runs ETL process to deal with original data from various databases and data warehouses, and then reorganized the data into the fishery rescue data mart. Next, online analytical processing (OLAP) are carried out and statistical reports are generated automatically. Particularly, quick configuration schemes are designed to configure query dimensions and OLAP data sets. The configuration file will be transformed into statistic interfaces automatically through a wizard-style process. The system provides various forms of reporting files, including crystal reports, flash graphical reports, and two-dimensional data grids. In addition, a wizard style interface was designed to guide users customizing inquiry processes, making it possible for nontechnical staffs to access customized reports. Characterized by quick configuration, safeness and flexibility, the system has been successfully applied in city fishery rescue department.

  12. Getting data out of the electronic patient record: critical steps in building a data warehouse for decision support.

    Science.gov (United States)

    Ebidia, A; Mulder, C; Tripp, B; Morgan, M W

    1999-01-01

    Health care has taken advantage of computers to streamline many clinical and administrative processes. However, the potential of health care information technology as a source of data for clinical and administrative decision support has not been fully explored. This paper describes the process of developing on-line analytical processing (OLAP) capacity from data generated in an on-line transaction processing (OLTP) system (the electronic patient record). We discuss the steps used to evaluate the EPR system, retrieve the data, and create an analytical data warehouse accessible for analysis. We also summarize studies based on the data (lab re-engineering, practice variation in diagnostic decision-making and evaluation of a clinical alert). Besides producing a useful data warehouse, the process also increased understanding of organizational and cost considerations in purchasing OLAP tools. We discuss the limitations of our approach and ways in which these limitations can be addressed.

  13. Modeling Optimal Scheduling for Pumping System to Minimize Operation Cost and Enhance Operation Reliability

    Directory of Open Access Journals (Sweden)

    Yin Luo

    2012-01-01

    Full Text Available Traditional pump scheduling models neglect the operation reliability which directly relates with the unscheduled maintenance cost and the wear cost during the operation. Just for this, based on the assumption that the vibration directly relates with the operation reliability and the degree of wear, it could express the operation reliability as the normalization of the vibration level. The characteristic of the vibration with the operation point was studied, it could be concluded that idealized flow versus vibration plot should be a distinct bathtub shape. There is a narrow sweet spot (80 to 100 percent BEP to obtain low vibration levels in this shape, and the vibration also follows similar law with the square of the rotation speed without resonance phenomena. Then, the operation reliability could be modeled as the function of the capacity and rotation speed of the pump and add this function to the traditional model to form the new. And contrast with the tradition method, the result shown that the new model could fix the result produced by the traditional, make the pump operate in low vibration, then the operation reliability could increase and the maintenance cost could decrease.

  14. Quark shell model using projection operators

    International Nuclear Information System (INIS)

    Ullah, N.

    1988-01-01

    Using the projection operators in the quark shell model, the wave functions for proton are calculated and expressions for calculating the wave function of neutron and also magnetic moment of proton and neutron are derived. (M.G.B.)

  15. Rancang Bangun Data Warehouse Untuk Analisis Kinerja Penjualan Pada Industri Dengan Model Spa-Dw

    Directory of Open Access Journals (Sweden)

    Randy Oktrima Putra

    2014-02-01

    Full Text Available A company, majorly company that active in commercial (profit orientation need to analyze their sales performance. By analyzing sales performance, company can increase their sales performance. One of method to analyze sales performance is by collecting historical data that relates to sales and then process that data so that produce information that show company sales performance.   A data warehouse is a set of data that has characteristic subject oriented, time variant, integrated, and nonvolatile that help company management in processing of decision making. Design of data warehouse is started from collecting data that relate to sales such as product, customer, sales area, sales transaction, etc. After collecting the data, next is data extraction and transformation. Data extraction is a process f or selecting data that will be loaded into data warehouse. Data transformation is making some change to the data afte r extracted to be more consistent. After transformation processing, data are loaded into data warehouse. Data in data warehouse is processed by OLAP (On Line Analytical Processing to produce information.  Information that are produced from data processing  by OLAP are chart and query reporting. Chart reporting are sales chart based on cement type, sales chart based on sales area, sales chart based on plant, monthly and year ly sales chart, and chart based on customer feedback. Query reporting are sales based on cement type, sales area, plant and customer.Keywords: Data warehouse; OLAP; Sales performance analysis; Ready mix market

  16. ICD-11 (JLMMS) and SCT Inter-Operation.

    Science.gov (United States)

    Mamou, Marzouk; Rector, Alan; Schulz, Stefan; Campbell, James; Solbrig, Harold; Rodrigues, Jean-Marie

    2016-01-01

    The goal of this work is to contribute to a smooth and semantically sound inter-operability between the ICD-11 (International Classification of Diseases-11th revision Joint Linearization for Mortality, Morbidity and Statistics) and SNOMED CT (SCT). To guarantee such inter-operation between a classification, characterized by a single hierarchy of mutually exclusive and exhaustive classes, as is the JLMMS successor of ICD-10 on the one hand, and the multi-hierarchical, ontology-based clinical terminology SCT on the other hand, we use ontology axioms that logically express generalizable truths. This is expressed by the compositional grammar of SCT, together with queries on axiomsof SCT. We test the feasibility of the method on the circulatory chapter of ICD-11 JLMMS and present limitations and results.

  17. Effective operator formalism for open quantum systems

    DEFF Research Database (Denmark)

    Reiter, Florentin; Sørensen, Anders Søndberg

    2012-01-01

    We present an effective operator formalism for open quantum systems. Employing perturbation theory and adiabatic elimination of excited states for a weakly driven system, we derive an effective master equation which reduces the evolution to the ground-state dynamics. The effective evolution...... involves a single effective Hamiltonian and one effective Lindblad operator for each naturally occurring decay process. Simple expressions are derived for the effective operators which can be directly applied to reach effective equations of motion for the ground states. We compare our method...

  18. Monet: a next-generation database kernel for query-intensive applications

    NARCIS (Netherlands)

    P.A. Boncz (Peter)

    2002-01-01

    htmlabstractMonet is a database kernel targeted at query-intensive, heavy analysis applications (the opposite of transaction processing), which include OLAP and data mining, but also go beyond the business domain in GIS processing, multi-media retrieval and XML. The clean sheet approach of Monet

  19. The Drill Down Benchmark

    NARCIS (Netherlands)

    P.A. Boncz (Peter); T. Rühl (Tim); F. Kwakkel

    1998-01-01

    textabstractData Mining places specific requirements on DBMS query performance that cannot be evaluated satisfactorily using existing OLAP benchmarks. The DD Benchmark - defined here - provides a practical case and yardstick to explore how well a DBMS is able to support Data Mining applications. It

  20. MonetDB/X100: Hyper-Pipelining Query Execution

    NARCIS (Netherlands)

    P.A. Boncz (Peter); M. Zukowski (Marcin); N.J. Nes (Niels)

    2005-01-01

    textabstractDatabase systems tend to achieve only low IPC (instructions-per-cycle) efficiency on modern CPUs in compute-intensive application areas like decision support, OLAP and multimedia retrieval. This paper starts with an in-depth investigation to the reason why this happens, focusing on the

  1. Super-scalar RAM-CPU cache compression

    NARCIS (Netherlands)

    M. Zukowski (Marcin); S. Héman (Sándor); N.J. Nes (Niels); P.A. Boncz (Peter)

    2005-01-01

    textabstractHigh-performance data-intensive query processing tasks like OLAP, data mining or scientific data analysis can be severely I/O bound, even when high-end RAID storage systems are used. Compression can alleviate this bottleneck only if encoding and decoding speeds significantly exceed RAID

  2. Super-Scalar RAM-CPU Cache Compression

    NARCIS (Netherlands)

    M. Zukowski (Marcin); S. Héman (Sándor); N.J. Nes (Niels); P.A. Boncz (Peter)

    2006-01-01

    textabstractHigh-performance data-intensive query processing tasks like OLAP, data mining or scientific data analysis can be severely I/O bound, even when high-end RAID storage systems are used. Compression can alleviate this bottleneck only if encoding and decoding speeds significantly exceed RAID

  3. Performance Optimization of Tensor Contraction Expressions for Many Body Methods in Quantum Chemistry

    International Nuclear Information System (INIS)

    Hartono, Albert; Lu, Qingda; Henretty, Thomas; Krishnamoorthy, Sriram; Zhang, Huaijian; Baumgartner, Gerald; Bernholdt, David E.; Nooijen, Marcel; Pitzer, Russell M.; Ramanujam, J.; Sadayappan, Ponnuswamy

    2009-01-01

    Complex tensor contraction expressions arise in accurate electronic structure models in quantum chemistry, such as the coupled cluster method. This paper addresses two complementary aspects of performance optimization of such tensor contraction expressions. Transformations using algebraic properties of commutativity and associativity can be used to significantly decrease the number of arithmetic operations required for evaluation of these expressions. The identification of common subexpressions among a set of tensor contraction expressions can result in a reduction of the total number of operations required to evaluate the tensor contractions. The first part of the paper describes an effective algorithm for operation minimization with common subexpression identification and demonstrates its effectiveness on tensor contraction expressions for coupled cluster equations. The second part of the paper highlights the importance of data layout transformation in the optimization of tensor contraction computations on modern processors. A number of considerations such as minimization of cache misses and utilization of multimedia vector instructions are discussed. A library for efficient index permutation of multi-dimensional tensors is described and experimental performance data is provided that demonstrates its effectiveness.

  4. Performance Optimization of Tensor Contraction Expressions for Many Body Methods in Quantum Chemistry

    International Nuclear Information System (INIS)

    Krishnamoorthy, Sriram; Bernholdt, David E.; Pitzer, R.M.; Sadayappan, Ponnuswamy

    2009-01-01

    Complex tensor contraction expressions arise in accurate electronic structure models in quantum chemistry, such as the coupled cluster method. This paper addresses two complementary aspects of performance optimization of such tensor contraction expressions. Transformations using algebraic properties of commutativity and associativity can be used to significantly decrease the number of arithmetic operations required for evaluation of these expressions. The identification of common subexpressions among a set of tensor contraction expressions can result in a reduction of the total number of operations required to evaluate the tensor contractions. The first part of the paper describes an effective algorithm for operation minimization with common subexpression identification and demonstrates its effectiveness on tensor contraction expressions for coupled cluster equations. The second part of the paper highlights the importance of data layout transformation in the optimization of tensor contraction computations on modern processors. A number of considerations, such as minimization of cache misses and utilization of multimedia vector instructions, are discussed. A library for efficient index permutation of multidimensional tensors is described, and experimental performance data is provided that demonstrates its effectiveness.

  5. Leituras de operárias

    Directory of Open Access Journals (Sweden)

    Betty Mindlin

    2008-03-01

    Full Text Available Defensora de causas sociais, paladina poética contra injustiças e desigualdade, Ecléa Bosi em seu livro Cultura Popular e Cultura de Massa: Leituras de Operárias, pesquisa as leituras de cerca de 50 operárias, procurando ver que acesso têm ao imaginário, aos livros, quais as suas condições de vida, como a sociedade industrial as privam da criação artística e literária, apesar de sua sede de conhecimento e de expressão.

  6. Relative boundedness and compactness theory for second-order differential operators

    Directory of Open Access Journals (Sweden)

    Don B. Hinton

    1997-01-01

    Full Text Available The problem considered is to give necessary and sufficient conditions for perturbations of a second-order ordinary differential operator to be either relatively bounded or relatively compact. Such conditions are found for three classes of operators. The conditions are expressed in terms of integral averages of the coefficients of the perturbing operator.

  7. Decreased store operated Ca2+ entry in dendritic cells isolated from mice expressing PKB/SGK-resistant GSK3.

    Science.gov (United States)

    Schmid, Evi; Yan, Jing; Nurbaeva, Meerim K; Russo, Antonella; Yang, Wenting; Faggio, Caterina; Shumilina, Ekaterina; Lang, Florian

    2014-01-01

    Dendritic cells (DCs), key players of immunity, are regulated by glycogen synthase kinase GSK3. GSK3 activity is suppressed by PKB/Akt and SGK isoforms, which are in turn stimulated by the PI3K pathway. Exposure to bacterial lipopolysaccharides increases cytosolic Ca(2+)-concentration ([Ca(2+)]i), an effect augmented in DCs isolated from mutant mice expressing PKB/SGK-resistant GSK3α,β (gsk3(KI) ). Factors affecting [Ca(2+)]i include Ca(2+)-release from intracellular stores (CRIS), store-operated Ca(2+)-entry (SOCE) through STIM1/STIM2-regulated Orai1, K(+)-dependent Na(+)/Ca(2+)-exchangers (NCKX), K(+)-independent Na(+)/Ca(2+)-exchangers (NCX) and calbindin-D28k. The present study explored whether PKB/SGK-dependent GSK3α, β-activity impacts on CRIS, SOCE, NCKX, NCX or calbindin. DCs were isolated from gsk3(KI) mice and respective wild-type mice (gsk3(WT) ), [Ca(2+)]i estimated from Fura2 fluorescence, Orai1, STIM1, STIM2 as well as calbindin-D28k protein abundance determined by Western blotting and mRNA levels quantified by real time PCR. As a result, thapsigargin-induced CRIS and SOCE were significantly blunted by GSK3-inhibitors SB216763 (1-10 µM, 30 min) or GSK-XIII (10 µM, 30 min) but were significantly lower in gsk3(WT) than in gsk3(KI) DCs. Orai1, STIM1 and STIM2 protein abundance was significantly lower and calbindin-D28k abundance significantly higher in gsk3(KI) than in gsk3(WT) DCs. Activity of NCKX and NCX was significantly higher in gsk3(KI) than in gsk3(WT) DCs and was significantly increased by SB216763 (1 µM, 30 min) or GSK-XIII (10 µM, 30 min). Treatment of gsk3(WT) DCs with SB216763 (1 µM, 4-24 h) or GSK-XIII (10 µM, 4-24 h) did not significantly modify the protein abundance of Orai1, STIM1 and STIM2. The present observations point to a dual role of GSK3 in the regulation of Ca(2+) in DCs. Acute inhibition of GSK3 blunted the increase of [Ca(2+)]i following CRIS and SOCE and stimulated NCKX/NCX activity. However, expression of PKB

  8. Querying Workflow Logs

    Directory of Open Access Journals (Sweden)

    Yan Tang

    2018-01-01

    Full Text Available A business process or workflow is an assembly of tasks that accomplishes a business goal. Business process management is the study of the design, configuration/implementation, enactment and monitoring, analysis, and re-design of workflows. The traditional methodology for the re-design and improvement of workflows relies on the well-known sequence of extract, transform, and load (ETL, data/process warehousing, and online analytical processing (OLAP tools. In this paper, we study the ad hoc queryiny of process enactments for (data-centric business processes, bypassing the traditional methodology for more flexibility in querying. We develop an algebraic query language based on “incident patterns” with four operators inspired from Business Process Model and Notation (BPMN representation, allowing the user to formulate ad hoc queries directly over workflow logs. A formal semantics of this query language, a preliminary query evaluation algorithm, and a group of elementary properties of the operators are provided.

  9. Word aligned bitmap compression method, data structure, and apparatus

    Science.gov (United States)

    Wu, Kesheng; Shoshani, Arie; Otoo, Ekow

    2004-12-14

    The Word-Aligned Hybrid (WAH) bitmap compression method and data structure is a relatively efficient method for searching and performing logical, counting, and pattern location operations upon large datasets. The technique is comprised of a data structure and methods that are optimized for computational efficiency by using the WAH compression method, which typically takes advantage of the target computing system's native word length. WAH is particularly apropos to infrequently varying databases, including those found in the on-line analytical processing (OLAP) industry, due to the increased computational efficiency of the WAH compressed bitmap index. Some commercial database products already include some version of a bitmap index, which could possibly be replaced by the WAH bitmap compression techniques for potentially increased operation speed, as well as increased efficiencies in constructing compressed bitmaps. Combined together, this technique may be particularly useful for real-time business intelligence. Additional WAH applications may include scientific modeling, such as climate and combustion simulations, to minimize search time for analysis and subsequent data visualization.

  10. Iterated Process Analysis over Lattice-Valued Regular Expressions

    DEFF Research Database (Denmark)

    Midtgaard, Jan; Nielson, Flemming; Nielson, Hanne Riis

    2016-01-01

    We present an iterated approach to statically analyze programs of two processes communicating by message passing. Our analysis operates over a domain of lattice-valued regular expressions, and computes increasingly better approximations of each process's communication behavior. Overall the work e...... extends traditional semantics-based program analysis techniques to automatically reason about message passing in a manner that can simultaneously analyze both values of variables as well as message order, message content, and their interdependencies.......We present an iterated approach to statically analyze programs of two processes communicating by message passing. Our analysis operates over a domain of lattice-valued regular expressions, and computes increasingly better approximations of each process's communication behavior. Overall the work...

  11. A unitary correlation operator method

    International Nuclear Information System (INIS)

    Feldmeier, H.; Neff, T.; Roth, R.; Schnack, J.

    1997-09-01

    The short range repulsion between nucleons is treated by a unitary correlation operator which shifts the nucleons away from each other whenever their uncorrelated positions are within the repulsive core. By formulating the correlation as a transformation of the relative distance between particle pairs, general analytic expressions for the correlated wave functions and correlated operators are given. The decomposition of correlated operators into irreducible n-body operators is discussed. The one- and two-body-irreducible parts are worked out explicitly and the contribution of three-body correlations is estimated to check convergence. Ground state energies of nuclei up to mass number A=48 are calculated with a spin-isospin-dependent potential and single Slater determinants as uncorrelated states. They show that the deduced energy-and mass-number-independent correlated two-body Hamiltonian reproduces all ''exact'' many-body calculations surprisingly well. (orig.)

  12. Mission Operations Working Group (MOWG) Report to the OMI Science Team

    Science.gov (United States)

    Fisher, Dominic M.

    2017-01-01

    This PowerPoint presentation will discuss Aura's current spacecraft and OMI insturment status, highlight any performance trends and impacts to OMI operations, identify any operational changes and express concerns or potential process improvements.

  13. Conducting Research on the International Space Station using the EXPRESS Rack Facilities

    Science.gov (United States)

    Thompson, Sean W.; Lake, Robert E.

    2016-01-01

    Eight "Expedite the Processing of Experiments to Space Station" (EXPRESS) Rack facilities are located within the International Space Station (ISS) laboratories to provide standard resources and interfaces for the simultaneous and independent operation of multiple experiments within each rack. Each EXPRESS Rack provides eight Middeck Locker Equivalent locations and two drawer locations for powered experiment equipment, also referred to as sub-rack payloads. Payload developers may provide their own structure to occupy the equivalent volume of one, two, or four lockers as a single unit. Resources provided for each location include power (28 Vdc, 0-500 W), command and data handling (Ethernet, RS-422, 5 Vdc discrete, +/- 5 Vdc analog), video (NTSC/RS 170A), and air cooling (0-200 W). Each rack also provides water cooling for two locations (500W ea.), one vacuum exhaust interface, and one gaseous nitrogen interface. Standard interfacing cables and hoses are provided on-orbit. One laptop computer is provided with each rack to control the rack and to accommodate payload application software. Four of the racks are equipped with the Active Rack Isolation System to reduce vibration between the ISS and the rack. EXPRESS Racks are operated by the Payload Operations Integration Center at Marshall Space Flight Center and the sub-rack experiments are operated remotely by the investigating organization. Payload Integration Managers serve as a focal to assist organizations developing payloads for an EXPRESS Rack. NASA provides EXPRESS Rack simulator software for payload developers to checkout payload command and data handling at the development site before integrating the payload with the EXPRESS Functional Checkout Unit for an end-to-end test before flight. EXPRESS Racks began supporting investigations onboard ISS on April 24, 2001 and will continue through the life of the ISS.

  14. Generalized operator canonical formalism and gauge invariance

    International Nuclear Information System (INIS)

    Fradkina, T.E.

    1988-01-01

    A direct proof is given in the functional representation of the invariance of the S-matrix constructed in the framework of the generalized operator canonical formalism. We find the traditional functional expression for the S-matrix (without point-splitting in the time factor) in the generalized phase space, as well as in the ghost configuration space. An explicit expression is obtained for the effective unitarizing Hamiltonian for gauge theories with constraints of arbitrary rank

  15. Euler Polynomials and Identities for Non-Commutative Operators

    OpenAIRE

    De Angelis, V.; Vignat, C.

    2015-01-01

    Three kinds of identities involving non-commutating operators and Euler and Bernoulli polynomials are studied. The first identity, as given by Bender and Bettencourt, expresses the nested commutator of the Hamiltonian and momentum operators as the commutator of the momentum and the shifted Euler polynomial of the Hamiltonian. The second one, due to J.-C. Pain, links the commutators and anti-commutators of the monomials of the position and momentum operators. The third appears in a work by Fig...

  16. BRST cohomology operators on string superforms

    International Nuclear Information System (INIS)

    Dao Vong Duc; Nguyen Thi Hong.

    1988-08-01

    BRST cohomology calculus in the space of superstring differential forms is treated in detail. The explicit expressions of cohomology operators are derived for superforms of arbitrary order. Various identities for the structure constants of the associated superalgebras are also given. (author). 16 refs

  17. Automatic Generation of Facial Expression Using Triangular Geometric Deformation

    OpenAIRE

    Jia-Shing Sheu; Tsu-Shien Hsieh; Ho-Nien Shou

    2014-01-01

    This paper presents an image deformation algorithm and constructs an automatic facial expression generation system to generate new facial expressions in neutral state. After the users input the face image in a neutral state into the system, the system separates the possible facial areas and the image background by skin color segmentation. It then uses the morphological operation to remove noise and to capture the organs of facial expression, such as the eyes, mouth, eyebrow, and nose. The fea...

  18. Droop Scheme With Consideration of Operating Costs

    DEFF Research Database (Denmark)

    Nutkani, I. U.; Loh, Poh Chiang; Blaabjerg, Frede

    2014-01-01

    considered even though they are different for different types of DGs. This letter thus proposes an alternative droop scheme, which can better distinguish the different operating characteristics and objectives of the DGs grouped together in a weighted droop expression. The power sharing arrived in the steady...... state will meet the intended objectives, as demonstrated in the experiment with a defined objective of minimizing the total microgrid operating cost....

  19. The tree technique and irreducible tensor operators for the quantum algebra suq (2). The algebra of irreducible tensor operators

    International Nuclear Information System (INIS)

    Smirnov, Yu.F.; Tolstoi, V.N.; Kharitonov, Yu.I.

    1993-01-01

    The tree technique for the quantum algebra su q (2) developed in an earlier study is used to construct the q analog of the algebra of irreducible tensor operators. The adjoint action of the algebra su q (2) on irreducible tensor operators is discussed, and the adjoint R matrix is introduced. A set of expressions is obtained for the matrix elements of various irreducible tensor operators and combinations of them. As an application, the recursion relations for the Clebsch-Gordan and Racah coefficients of the algebra su q (2) are derived. 16 refs

  20. Multidimensional Data Model and Query Language for Informetrics.

    Science.gov (United States)

    Niemi, Timo; Hirvonen, Lasse; Jarvelin, Kalervo

    2003-01-01

    Discusses multidimensional data analysis, or online analytical processing (OLAP), which offer a single subject-oriented source for analyzing summary data based on various dimensions. Develops a conceptual/logical multidimensional model for supporting the needs of informetrics, including a multidimensional query language whose basic idea is to…

  1. Adaptive query parallelization in multi-core column stores

    NARCIS (Netherlands)

    M.M. Gawade (Mrunal); M.L. Kersten (Martin); M.M. Gawade (Mrunal); M.L. Kersten (Martin)

    2016-01-01

    htmlabstractWith the rise of multi-core CPU platforms, their optimal utilization for in-memory OLAP workloads using column store databases has become one of the biggest challenges. Some of the inherent limi- tations in the achievable query parallelism are due to the degree of parallelism

  2. Contextualizing Data Warehouses with Documents

    DEFF Research Database (Denmark)

    Perez, Juan Manuel; Berlanga, Rafael; Aramburu, Maria Jose

    2008-01-01

    warehouse with a document warehouse, resulting in a contextualized warehouse. Thus, the user first selects an analysis context by supplying some keywords. Then, the analysis is performed on a novel type of OLAP cube, called an R-cube, which is materialized by retrieving and ranking the documents...

  3. Particles and Dirac-type operators on curved spaces

    International Nuclear Information System (INIS)

    Visinescu, Mihai

    2003-01-01

    We review the geodesic motion of pseudo-classical particles in curved spaces. Investigating the generalized Killing equations for spinning spaces, we express the constants of motion in terms of Killing-Yano tensors. Passing from the spinning spaces to the Dirac equation in curved backgrounds we point out the role of the Killing-Yano tensors in the construction of the Dirac-type operators. The general results are applied to the case of the four-dimensional Euclidean Taub-Newman-Unti-Tamburino space. From the covariantly constant Killing-Yano tensors of this space we construct three new Dirac-type operators which are equivalent with the standard Dirac operator. Finally the Runge-Lenz operator for the Dirac equation in this background is expressed in terms of the fourth Killing-Yano tensor which is not covariantly constant. As a rule the covariantly constant Killing-Yano tensors realize certain square roots of the metric tensor. Such a Killing-Yano tensor produces simultaneously a Dirac-type operator and the generator of a one-parameter Lie group connecting this operator with the standard Dirac one. On the other hand, the not covariantly constant Killing-Yano tensors are important in generating hidden symmetries. The presence of not covariantly constant Killing-Yano tensors implies the existence of non-standard supersymmetries in point particle theories on curved background. (author)

  4. Software in support of fuel operation in WWERS

    International Nuclear Information System (INIS)

    Evdokimov, I.A; Novikov, V.V; Ugrumov, A.V; Shishkin, A.A

    2013-01-01

    A software package comprising computer codes and fuel monitoring tools is under development in Russia in support of WWER fuel operation. The software package includes an expert computer system designed for failure diagnosis in course of reactor operation, prediction of activity evolution in primary coolant and express analysis of pellet-to-cladding mechanical interaction (PCMI) on rod-by-rod basis under normal and transient modes of operation. Coupled with the expert system, the first version of a graphical interface computer program is developed for NPP operating bodies. One of the features of this program is to launch automatically a fuel performance code for a series of detailed calculations for fuel rods with severe PCMI. The particular rods for calculations are determined by the expert system during the express core analysis. A greater attention is paid to recent results in prediction of fuel behavior after a primary failure has occurred. One of the major risks to further operation of leaking fuel comes from secondary fuel degradation due to massive cladding hydriding. Threshold conditions for initiation of secondary hydriding have been found on the basis of physical modeling. Final criteria of secondary failure occurrence were deduced by applying the model to analysis of post-irradiation examinations of leaking WWER fuel. (authors)

  5. Beyond Safe Operating Space: Finding Chemical Footprinting Feasible

    DEFF Research Database (Denmark)

    Posthuma, Leo; Bjørn, Anders; Zijp, Michiel C.

    2014-01-01

    undefined boundary in their selection of planetary boundaries delineating the “safe operating space for humanity”. Can we use the well-known concept of “ecological footprints” to express a chemical pollution boundary aimed at preventing the overshoot of the Earth’s capacity to assimilate environmental...... scenarios that allow us to avoid “chemical overshoot” beyond the Earth’s safe operating space....

  6. Automated emergency operating procedures

    International Nuclear Information System (INIS)

    Perez-Ramirez, G.; Nelson, P.F.

    1990-01-01

    This paper describes the development of a training tool for the symptom oriented emergency operating procedures used at the Laguna Verde Nuclear Power Plant. EOPs and operator training are intended to assist the operator for managing accident situations. A prototype expert system based on the EOPs has been developed for operator training. The demonstration expert system was developed using a commercial shell. The knowledge base consists of two parts. The specific operator actions to be executed for 5 selected accident sequences and the EOPs steps for the reactor pressure vessel control of the water level, pressure, and power. The knowledge is expressed in the form of IF-THEN production rules. A typical training session will display a set of conditions and will prompt the trainee to indicate the appropriate step to perform. This mode will guide the trainee through selected accident sequences. A second mode of the expert system will prompt the trainee for the current plant conditions and the expert system will respond with the EOPs which are required to be performed under these conditions. This allows the trainee to study What if situations

  7. Investigating and improving student understanding of quantum mechanical observables and their corresponding operators in Dirac notation

    Science.gov (United States)

    Marshman, Emily; Singh, Chandralekha

    2018-01-01

    In quantum mechanics, for every physical observable, there is a corresponding Hermitian operator. According to the most common interpretation of quantum mechanics, measurement of an observable collapses the quantum state into one of the possible eigenstates of the operator and the corresponding eigenvalue is measured. Since Dirac notation is an elegant notation that is commonly used in upper-level quantum mechanics, it is important that students learn to express quantum operators corresponding to observables in Dirac notation in order to apply the quantum formalism effectively in diverse situations. Here we focus on an investigation that suggests that, even though Dirac notation is used extensively, many advanced undergraduate and PhD students in physics have difficulty expressing the identity operator and other Hermitian operators corresponding to physical observables in Dirac notation. We first describe the difficulties students have with expressing the identity operator and a generic Hermitian operator corresponding to an observable in Dirac notation. We then discuss how the difficulties found via written surveys and individual interviews were used as a guide in the development of a quantum interactive learning tutorial (QuILT) to help students develop a good grasp of these concepts. The QuILT strives to help students become proficient in expressing the identity operator and a generic Hermitian operator corresponding to an observable in Dirac notation. We also discuss the effectiveness of the QuILT based on in-class evaluations.

  8. The three-particle scattering operator in the correlation pattern representation

    International Nuclear Information System (INIS)

    De La Rubia, J.; Brey, J.J.; Moreno, F.

    1976-01-01

    It is shown that the ''correlation pattern representation'' permits the direct establishing of equivalence between the three-particle kinetic evolution operator obtained by means of Prigogine's method and the corresponding expression derived by Green and Cohen. Both expressions take into account the finite duration of collisions in a strictly equivalent way

  9. A new multidimensional model with text dimensions: definition and implementation

    Directory of Open Access Journals (Sweden)

    MariaJ. Martin-Bautista

    2013-02-01

    Full Text Available We present a new multidimensional model with textual dimensions based on a knowledge structure extracted from the texts, where any textual attribute in a database can be processed, and not only XML texts. This dimension allows to treat the textual data in the same way as the non-textual one in an automatic way, without user's intervention, so all the classical operations in the multidimensional model can been defined for this textual dimension. While most of the models dealing with texts that can be found in the literature are not implemented, in this proposal, the multidimensional model and the OLAP system have been implemented in a software tool, so it can be tested on real data. A case study with medical data is included in this work.

  10. Unified Approach in the DSS Development Process

    Directory of Open Access Journals (Sweden)

    2007-01-01

    Full Text Available The structure of today's decision support environment become very complex due to new generation of Business Intelligence applications and technologies like Data Warehouse, OLAP (On Line Analytical Processing and Data Mining. In this respect DSS development process are not simple and needs an adequate methodology or framework able to manage different tools and platforms to achieve manager's requirements. The DSS development process must be view like a unified and iterative set of activities and operations. The new techniques based on Unified Process (UP methodology and UML (Unified Modeling Language it seems to be appropriate for DSS development using prototyping and RAD (Rapid Application Development techniques. In this paper we present a conceptual framework for development and integrate Decision Support Systems using Unified Process Methodology and UML.

  11. Gene expression programming for power system static security ...

    African Journals Online (AJOL)

    user

    Keywords: static security, gene expression programming, probabilistic neural network ... Hence digital computers are usually installed in operations control centers to gather ...... power system protection, and applications of AI in power systems.

  12. What Can Hierarchies Do for Data Streams?

    DEFF Research Database (Denmark)

    Yin, Xuepeng; Pedersen, Torben Bach

    2007-01-01

    Abstract. Much effort has been put into building data streams management systems for querying data streams. However, the query languages have mostly been SQL-based and aimed for low-level analysis of base data; therefore, there has been little work on supporting OLAP-like queries that provide rea...

  13. Venus Express set for launch to the cryptic planet

    Science.gov (United States)

    2005-10-01

    heading east. This injection is done by the first burn of the Fregat engine, due to take place at 06:52 CEST (04:52 GMT). At 08:03 CEST, about one hour and twenty minutes after lift-off and after an almost full circle around Earth, the third phase starts. While flying over Africa, Fregat will ignite for a second time to escape Earth orbit and head into the hyperbolic trajectory that will bring the spacecraft to Venus. After this burn, Fregat will gently release Venus Express, by firing a separation mechanism. With this last step, the launcher will have concluded its task. Plenty of ground activities for a successful trip Once separated from Fregat at 08:21 CEST, Venus Express will be awoken from its dormant status by a series of automatic on-board commands, such as the activation of its propulsion and thermal control systems, the deployment of solar arrays and manoeuvres to ‘orient’ itself in space. From this moment the spacecraft comes under the control of ESA’s European Space Operations Centre (ESOC) for the full duration of the mission. The flight control team co-ordinate and manage a network of ESA ground stations and antennas around the globe, to regularly communicate with the spacecraft. The New Norcia station in Australia and the Kourou station in French Guiana will in turn communicate with Venus Express in the initial phase of the mission. The first opportunity to receive a signal and confirm that the spacecraft is in good health will be the privilege of the New Norcia station about two hours after launch. In this early phase of the mission, once ESOC has taken full control of the satellite, the spacecraft will be fully activated. Operations will also include two burns of the Venus Express thrusters, to correct any possible error in the trajectory after separation from Fregat. On 28 October, the newly inaugurated Cebreros station in Spain, with its 35-metre antenna, will start to take an active part in ground network operations to relay information between

  14. Determination of Model Kinetics for Forced Unsteady State Operation of Catalytic CH4 Oxidation

    Directory of Open Access Journals (Sweden)

    Effendy Mohammad

    2016-01-01

    Full Text Available The catalytic oxidation of methane for abating the emission vented from coal mine or natural gas transportation has been known as most reliable method. A reverse flow reactor operation has been widely used to oxidize this methane emission due to its capability for autothermal operation and heat production. The design of the reverse flow reactor requires a proper kinetic rate expression, which should be developed based on the operating condition. The kinetic rate obtained in the steady state condition cannot be applied for designing the reactor operated under unsteady state condition. Therefore, new approach to develop the dynamic kinetic rate expression becomes indispensable, particularly for periodic operation such as reverse flow reactor. This paper presents a novel method to develop the kinetic rate expression applied for unsteady state operation. The model reaction of the catalytic methane oxidation over Pt/-Al2O3 catalyst was used with kinetic parameter determined from laboratory experiments. The reactor used was a fixed bed, once-through operation, with a composition modulation in the feed gas. The switching time was set at 3 min by varying the feed concentration, feed flow rate, and reaction temperature. The concentrations of methane in the feed and product were measured and analysed using gas chromatography. The steady state condition for obtaining the kinetic rate expression was taken as a base case and as a way to judge its appropriateness to be applied for dynamic system. A Langmuir-Hinshelwood reaction rate model was developed. The time period during one cycle was divided into some segments, depending on the ratio of CH4/O2. The experimental result shows that there were kinetic regimes occur during one cycle: kinetic regime controlled by intrinsic surface reaction and kinetic regime controlled by external diffusion. The kinetic rate obtained in the steady state operation was not appropriate when applied for unsteady state operation

  15. AVS/Express (application visualization system) user's guide

    Energy Technology Data Exchange (ETDEWEB)

    Kato, Katsumi [Research Organization for Information Science Technology, Tokai, Ibaraki (Japan); Kume, Etsuo [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2002-09-01

    Computer and network environment for image processing has been developed and maintained under the course of establishing a distributed processing environment by the information system operating division. We introduced a server for image processing, AVS/Express for image processing software and Stereo viewing system. This report summarizes the information to use AVS/Express efficiently in the computer environment for image processing. (author)

  16. Theory and applications of generalized operator transforms for diagonalization of spin hamiltonians

    International Nuclear Information System (INIS)

    Schweiger, A.; Graf, F.; Rist, G.; Guenthard, Hs.H.

    1976-01-01

    A generalized transform formalism for vector operators is devised for diagonalization of a rather wide class of spin hamiltonians. The operator technique leads to equations for transformation matrices, for which analytical solutions are given. These allow analytical formulation of the transformed electron Zeeman term, the sum of the magnetic hyperfine and nuclear Zeeman term, the electric quadrupole term and the electronic and nuclear Zeeman coupling terms. The angular dependence of energy eigenvalues, frequencies and line strengths of ESR and ENDOR transitions to first order will be expressed as compact bilinear and quadratic forms of the columns of the matrix relating the molecular coordinate system to the laboratory system. Thereby the explicit calculation of rotation matrices may be completely avoided, though the latter formally express the operator transforms. The generalized operator transform is also carried out for the off-diagonal blocks originating from hyperfine interaction terms. This allows the second order energy terms to be expressed explicitly as compact hermitean forms of a simple structure, in particular the explicit structure of mixing terms between hyperfine interactions of different (sets of) nuclei is obtained. The relationship to the conventional Bleaney transform is discussed and the analogy to the generalized operator transform is worked out. (Auth.)

  17. The Unbalanced Linguistic Aggregation Operator in Group Decision Making

    Directory of Open Access Journals (Sweden)

    Li Zou

    2012-01-01

    Full Text Available Many linguistic aggregation methods have been proposed and applied in the linguistic decision-making problems. In practice, experts need to assess a number of values in a side of reference domain higher than in the other one; that is, experts use unbalanced linguistic values to express their evaluation for problems. In this paper, we propose a new linguistic aggregation operator to deal with unbalanced linguistic values in group decision making, we adopt 2-tuple representation model of linguistic values and linguistic hierarchies to express unbalanced linguistic values, and moreover, we present the unbalanced linguistic ordered weighted geometric operator to aggregate unbalanced linguistic evaluation values; a comparison example is given to show the advantage of our method.

  18. Positive Quasi Linear Operator Formulation

    International Nuclear Information System (INIS)

    Berry, L.A.; Jaeger, E.F.

    2005-01-01

    Expressions for the RF quasi-linear operator are biquadratic sums over the Fourier modes (or FLR equivalent) that describe the RF electric field with a kernel that is a function of the two wave vectors, k-vector L and k-vector R , in the sum. As a result of either an implicit or explicit average over field lines or flux surfaces, this kernel only depends on one parallel wave vector, conventionally k R -vector. When k-vector is an independent component of the representation for E, the sums are demonstrably positive. However, except for closed field line systems, k-vector is dependent on the local direction of the equilibrium magnetic field, and, empirically, the absorbed energy and quasi-linear diffusion coefficients are observed to have negative features. We have formally introduced an independent k-vector sum by Fourier transforming the RF electric field (assuming straight field lines) using a field-line-length coordinate. The resulting expression is positive. We have modeled this approach by calculating the quasi linear operator for 'modes' with fixed k-vector. We form these modes by discretizing k-vector and then assigning all of the Fourier components with k-vectorthat fall within a given k-vector bin to that k-vector mode. Results will be shown as a function of the number of bins. Future work will involve implementing the expressions derived from the Fourier transform and evaluating the dependence on field line length

  19. Tunable Control of an Escherichia coli Expression System for the Overproduction of Membrane Proteins by Titrated Expression of a Mutant lac Repressor.

    Science.gov (United States)

    Kim, Seong Keun; Lee, Dae-Hee; Kim, Oh Cheol; Kim, Jihyun F; Yoon, Sung Ho

    2017-09-15

    Most inducible expression systems suffer from growth defects, leaky basal induction, and inhomogeneous expression levels within a host cell population. These difficulties are most prominent with the overproduction of membrane proteins that are toxic to host cells. Here, we developed an Escherichia coli inducible expression system for membrane protein production based on titrated expression of a mutant lac repressor (mLacI). Performance of the mLacI inducible system was evaluated in conjunction with commonly used lac operator-based expression vectors using a T7 or tac promoter. Remarkably, expression of a target gene can be titrated by the dose-dependent addition of l-rhamnose, and the expression levels were homogeneous in the cell population. The developed system was successfully applied to overexpress three membrane proteins that were otherwise difficult to produce in E. coli. This gene expression control system can be easily applied to a broad range of existing protein expression systems and should be useful in constructing genetic circuits that require precise output signals.

  20. Personal optical disk library (PODL) for knowledge engineering

    Science.gov (United States)

    Wang, Hong; Jia, Huibo; Xu, Duanyi

    2001-02-01

    This paper describes the structure of Personal Optical Disk Library (PODL), a kind of large capacity (40 GB) optical storage equipment for personal usage. With the knowledge engineering technology integrated in the PODL, it can be used on knowledge query, knowledge discovery, Computer-Aided Instruction (CAI) and Online Analysis Process (OLAP).

  1. Coordinate, Momentum and Dispersion operators in Phase space representation

    International Nuclear Information System (INIS)

    Rakotoson, H.; Raoelina Andriambololona; Ranaivoson, R.T.R.; Raboanary, R.

    2017-07-01

    The aim of this paper is to present a study on the representations of coordinate, momentum and dispersion operators in the framework of a phase space representation of quantum mechanics that we have introduced and studied in previous works. We begin in the introduction section with a recall about the concept of representation of operators on wave function spaces. Then, we show that in the case of the phase space representation the coordinate and momentum operators can be represented either with differential operators or with matrices. The explicit expressions of both the differential operators and matrices representations are established. Multidimensional generalization of the obtained results are performed and phase space representation of dispersion operators are given.

  2. TNF-{alpha} mediates the stimulation of sclerostin expression in an estrogen-deficient condition

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Beom-Jun [Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of); Bae, Sung Jin [Health Promotion Center, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of); Lee, Sun-Young; Lee, Young-Sun; Baek, Ji-Eun; Park, Sook-Young [Asan Institute for Life Sciences, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of); Lee, Seung Hun [Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of); Koh, Jung-Min, E-mail: jmkoh@amc.seoul.kr [Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of); Kim, Ghi Su [Division of Endocrinology and Metabolism, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Poongnap2-Dong, Seoul (Korea, Republic of)

    2012-07-20

    Highlights: Black-Right-Pointing-Pointer Estrogen deprivation stimulates the bony sclerostin levels with reversal by estrogen. Black-Right-Pointing-Pointer TNF-{alpha} increases the activity and expression of MEF2 in UMR-106 cells. Black-Right-Pointing-Pointer TNF-{alpha} blocker prevents the stimulation of bony sclerostin expression by ovariectomy. Black-Right-Pointing-Pointer No difference in bony sclerostin expression between sham-operated and ovariectomized nude mice. -- Abstract: Although recent clinical studies have suggested a possible role for sclerostin, a secreted Wnt antagonist, in the pathogenesis of postmenopausal osteoporosis, the detailed mechanisms how estrogen deficiency regulates sclerostin expression have not been well-elucidated. Bilateral ovariectomy or a sham operation in female C57BL/6 mice and BALB/c nude mice was performed when they were seven weeks of age. The C57BL/6 mice were intraperitoneally injected with phosphate-buffered serum (PBS), 5 {mu}g/kg {beta}-estradiol five times per week for three weeks, or 10 mg/kg TNF-{alpha} blocker three times per week for three weeks. Bony sclerostin expression was assessed by immunohistochemistry staining in their femurs. The activity and expression of myocyte enhancer factors 2 (MEF2), which is essential for the transcriptional activation of sclerostin, in rat UMR-106 osteosarcoma cells were determined by luciferase reporter assay and western blot analysis, respectively. Bony sclerostin expression was stimulated by estrogen deficiency and it was reversed by estradiol supplementation. When the UMR-106 cells were treated with well-known, estrogen-regulated cytokines, only TNF-{alpha}, but not IL-1 and IL-6, increased the MEF2 activity. Consistently, TNF-{alpha} also increased the nuclear MEF2 expression. Furthermore, the TNF-{alpha} blocker prevented the stimulation of bony sclerostin expression by ovariectomy. We also found that there was no difference in sclerostin expression between ovariectomized

  3. TNF-α mediates the stimulation of sclerostin expression in an estrogen-deficient condition

    International Nuclear Information System (INIS)

    Kim, Beom-Jun; Bae, Sung Jin; Lee, Sun-Young; Lee, Young-Sun; Baek, Ji-Eun; Park, Sook-Young; Lee, Seung Hun; Koh, Jung-Min; Kim, Ghi Su

    2012-01-01

    Highlights: ► Estrogen deprivation stimulates the bony sclerostin levels with reversal by estrogen. ► TNF-α increases the activity and expression of MEF2 in UMR-106 cells. ► TNF-α blocker prevents the stimulation of bony sclerostin expression by ovariectomy. ► No difference in bony sclerostin expression between sham-operated and ovariectomized nude mice. -- Abstract: Although recent clinical studies have suggested a possible role for sclerostin, a secreted Wnt antagonist, in the pathogenesis of postmenopausal osteoporosis, the detailed mechanisms how estrogen deficiency regulates sclerostin expression have not been well-elucidated. Bilateral ovariectomy or a sham operation in female C57BL/6 mice and BALB/c nude mice was performed when they were seven weeks of age. The C57BL/6 mice were intraperitoneally injected with phosphate-buffered serum (PBS), 5 μg/kg β-estradiol five times per week for three weeks, or 10 mg/kg TNF-α blocker three times per week for three weeks. Bony sclerostin expression was assessed by immunohistochemistry staining in their femurs. The activity and expression of myocyte enhancer factors 2 (MEF2), which is essential for the transcriptional activation of sclerostin, in rat UMR-106 osteosarcoma cells were determined by luciferase reporter assay and western blot analysis, respectively. Bony sclerostin expression was stimulated by estrogen deficiency and it was reversed by estradiol supplementation. When the UMR-106 cells were treated with well-known, estrogen-regulated cytokines, only TNF-α, but not IL-1 and IL-6, increased the MEF2 activity. Consistently, TNF-α also increased the nuclear MEF2 expression. Furthermore, the TNF-α blocker prevented the stimulation of bony sclerostin expression by ovariectomy. We also found that there was no difference in sclerostin expression between ovariectomized nude mice and sham-operated nude mice. In conclusion, these results suggest that TNF-α originating from T cells may be at least in part

  4. CHEMICAL CHARACTERISTICS OF LAKE KIVU, RWANDA Olap

    African Journals Online (AJOL)

    USER

    2012-08-05

    Aug 5, 2012 ... Forestry, University of Ibadan, Ibadan, Nigeria ... concentration in the lake water does not constitute any serious health risk to both man ..... tropics is adapted. .... personnel and laboratory space used for the research work. .... Water Quality of Angaw River in southern – eastern coastal plains of Ghana. W. Afri ...

  5. Compressing Data Cube in Parallel OLAP Systems

    Directory of Open Access Journals (Sweden)

    Frank Dehne

    2007-03-01

    Full Text Available This paper proposes an efficient algorithm to compress the cubes in the progress of the parallel data cube generation. This low overhead compression mechanism provides block-by-block and record-by-record compression by using tuple difference coding techniques, thereby maximizing the compression ratio and minimizing the decompression penalty at run-time. The experimental results demonstrate that the typical compression ratio is about 30:1 without sacrificing running time. This paper also demonstrates that the compression method is suitable for Hilbert Space Filling Curve, a mechanism widely used in multi-dimensional indexing.

  6. Deriving Trading Rules Using Gene Expression Programming

    Directory of Open Access Journals (Sweden)

    Adrian VISOIU

    2011-01-01

    Full Text Available This paper presents how buy and sell trading rules are generated using gene expression programming with special setup. Market concepts are presented and market analysis is discussed with emphasis on technical analysis and quantitative methods. The use of genetic algorithms in deriving trading rules is presented. Gene expression programming is applied in a form where multiple types of operators and operands are used. This gives birth to multiple gene contexts and references between genes in order to keep the linear structure of the gene expression programming chromosome. The setup of multiple gene contexts is presented. The case study shows how to use the proposed gene setup to derive trading rules encoded by Boolean expressions, using a dataset with the reference exchange rates between the Euro and the Romanian leu. The conclusions highlight the positive results obtained in deriving useful trading rules.

  7. Projection operator and propagator for an arbitrary integral spin

    CERN Document Server

    Huang Shi Zhong; Wu Ning; Zheng Zhi Peng

    2002-01-01

    Based on the solution of the Bargmann-Wigner equation for an arbitrary integral spin, a direct derivation of the projection operator and propagator for an arbitrary integral spin is presented. The explicit form for the spin projection operators constructed by Behrends and Fronsdal is confirmed. The commutation rules and a general expression for the Feynman propagator for a free particle of arbitrary integral spin are deduced

  8. Contribution to computer aided design of digital circuits - Minimization of alphanumeric expressions - Program CHOPIN

    International Nuclear Information System (INIS)

    Blanca, Ernest

    1974-10-01

    Alpha-numeric boolean expressions, written in the form of sums of products and/or products of sums with many brackets, may be minimized in two steps: syntaxic recognition analysis using precedence operator grammar, syntaxic reduction analysis. These two phases of execution and the different programs of the corresponding machine algorithm are described. Examples of minimization of alpha-numeric boolean expressions written with the help of brackets, utilisation note of the program CHOPIN and theoretical considerations related to language, grammar, precedence operator grammar, sequential systems, boolean sets, boolean representations and treatments of boolean expressions, boolean matrices and their use in grammar theory, are discussed and described. (author) [fr

  9. Elementary operations on histograms - translation - contraction - expansion; Operations elementaires sur histogrammes translation, contraction, dilatation

    Energy Technology Data Exchange (ETDEWEB)

    Becker, A [Commissariat a l' Energie Atomique, Saclay (France). Centre d' Etudes Nucleaires

    1968-07-01

    A simple model is proposed for describing the working of analyzer systems which carry out successively the transformations from a physical system to its analogue expression, and then finally to a numerical scale. The model leads to a process for determining the physical zero in which, intentionally, only instrumental adjustments of immediate access are made to intervene. When it is possible to consider that the indispensable knowledge of the correspondence between the physical origin and the numerical scale has been acquired, one can correct by numerical treatment the possible deformations, which affect the recorded distributions in spite of the use of electronic stabilizing systems. With this in view, a programme of very general structure has been written which makes it possible to carry out simple operations of the translation type and homothetic transformations with constant area; the major part of is this report is devoted to a description of this programme and to its expression in MAGE II and FORTRAN IV. (author) [French] Pour la description du fonctionnement des systemes analyseurs realisant successivement les transformations faisant passer d'un systeme physique a son expression analogique, puis enfin, a une echelle numerique, on propose un modele simple. Ce dernier conduit a un procede de determination de zero physique, dans lequel, c'est a dessein, que l'on ne fait intervenir que des reglages instrumentaux d'acces immediat. Lorsque l'indispensable connaissance de la correspondance entre l'origine physique et l'echelle numerique peut etre consideree comme acquise, les eventuelles deformations qui, malgre l'utilisation de systemes stabilisateurs electroniques, affectent les distributions enregistrees peuvent etre corrigees par des traitements numeriques. Dans ce dernier but, il a ete ecrit un programme de structure tres generale, capable d'effectuer des operations simples du type translation et homotheties avec conservation d'aires; sa description et son

  10. [Nuclear factor-kappaB mRNA and protein expression in stomach tissue of rats with gastric ulcer recurrence and effect of jianwei yuyang granule on its expression].

    Science.gov (United States)

    Ling, Jiang-Hong; Li, Jia-Bang; Shen, Ding-Zhu; Zhou, Bing

    2006-03-01

    To observe the inflammatory reaction, nuclear factor-kappaB (NF-kappaB) mRNA and protein expression in stomach tissue of rats with gastric ulcer recurrence and the effect of Jianwei Yuyang granule (JYG) on them. Gastric ulcer and its recurrent lesion were successively induced by acetic acid and interliukin1-beta (IL-1beta), and the model rats were divided into the sham operation group, the model group, the omeprazole (correction of omepraxole) group and the JYG group to observe the state of chronic inflammatory cell, neutrophil count, NF-kappaBmRNA and protein expression in stomach tissue. On the 16th and 92th day after administration, the increase of chronic inflammatory cell, neutrophil, NF-kappaBmRNA and protein expression in the model group was more significant than those in the sham operated group (P ulcer induced by acetic acid. JYG may suppress inflammatory reaction by inhibiting the activation and expression of NF-kappaB in stomach tissue, which may be one of the mechanisms of JYG in preventing the recurrence of gastric ulcer.

  11. Comparison with Other Techniques

    Science.gov (United States)

    Sacco, Giovanni Maria; Ferré, Sébastien; Tzitzikas, Yannis

    This chapter compares dynamic taxonomies with the other main approaches to information access and discusses analogies and differences. The approaches analyzed range from traditional retrieval paradigms, such as queries on structured data, to the most recent approaches, including the current effort on the Semantic Web: queries on structured data, and OLAP data analysis techniques;

  12. Recursive Matrix Inverse Update On An Optical Processor

    Science.gov (United States)

    Casasent, David P.; Baranoski, Edward J.

    1988-02-01

    A high accuracy optical linear algebraic processor (OLAP) using the digital multiplication by analog convolution (DMAC) algorithm is described for use in an efficient matrix inverse update algorithm with speed and accuracy advantages. The solution of the parameters in the algorithm are addressed and the advantages of optical over digital linear algebraic processors are advanced.

  13. Ethics in an operations management course.

    Science.gov (United States)

    Rudnicka, Ewa A

    2005-10-01

    Graduates of the management major at the University of Pittsburgh at Greensburg find employment in a variety of organizations. As future managers with employees from different professions, students expressed an interest in discussing ethics cases in the operations management class. The semester starts with students familiarizing themselves with various professional and corporate codes of ethics. Throughout the semester a number of short ethics' cases in operations' areas such as inventory management, scheduling, facility location, and product design are introduced to illustrate ethical issues that a manager and his/her employees might face. Students prepare individual responses before the in-class discussions. The semester ends with a long group ethics case discussion and formal case presentations. In the end-of-semester survey, students responded very favorably to an ethics component in the operations management class.

  14. Low-resolution expression recognition based on central oblique average CS-LBP with adaptive threshold

    Science.gov (United States)

    Han, Sheng; Xi, Shi-qiong; Geng, Wei-dong

    2017-11-01

    In order to solve the problem of low recognition rate of traditional feature extraction operators under low-resolution images, a novel algorithm of expression recognition is proposed, named central oblique average center-symmetric local binary pattern (CS-LBP) with adaptive threshold (ATCS-LBP). Firstly, the features of face images can be extracted by the proposed operator after pretreatment. Secondly, the obtained feature image is divided into blocks. Thirdly, the histogram of each block is computed independently and all histograms can be connected serially to create a final feature vector. Finally, expression classification is achieved by using support vector machine (SVM) classifier. Experimental results on Japanese female facial expression (JAFFE) database show that the proposed algorithm can achieve a recognition rate of 81.9% when the resolution is as low as 16×16, which is much better than that of the traditional feature extraction operators.

  15. XWeB: The XML Warehouse Benchmark

    Science.gov (United States)

    Mahboubi, Hadj; Darmont, Jérôme

    With the emergence of XML as a standard for representing business data, new decision support applications are being developed. These XML data warehouses aim at supporting On-Line Analytical Processing (OLAP) operations that manipulate irregular XML data. To ensure feasibility of these new tools, important performance issues must be addressed. Performance is customarily assessed with the help of benchmarks. However, decision support benchmarks do not currently support XML features. In this paper, we introduce the XML Warehouse Benchmark (XWeB), which aims at filling this gap. XWeB derives from the relational decision support benchmark TPC-H. It is mainly composed of a test data warehouse that is based on a unified reference model for XML warehouses and that features XML-specific structures, and its associate XQuery decision support workload. XWeB's usage is illustrated by experiments on several XML database management systems.

  16. Some Normal Intuitionistic Fuzzy Heronian Mean Operators Using Hamacher Operation and Their Application

    Directory of Open Access Journals (Sweden)

    Guofang Zhang

    2018-06-01

    Full Text Available Hamacher operation is a generalization of the algebraic and Einstein operation and expresses a family of binary operation in the unit interval [0,1]. Heronian mean can deal with correlations of different criteria or input arguments and does not bring out repeated calculation. The normal intuitionistic fuzzy numbers (NIFNs can depict normal distribution information in practical decision making. A decision-making problem was researched under the NIFN environment in this study, and a new multi-criteria group decision-making (MCGDM approach is herein introduced on the basis of Hamacher operation. Firstly, according to Hamacher operation, some operational laws of NIFNs are presented. Secondly, it is noted that Heronian mean not only takes into account mutuality between the attribute values once, but also considers the correlation between input argument and itself. Therefore, in order to aggregate NIFN information, we developed some operators and studied their properties. These operators include Hamacher Heronian mean (NIFHHM, Hamacher weighted Heronian mean (NIFHWHM, Hamacher geometric Heronian mean (NIFHGHM, and Hamacher weighted geometric Heronian mean (NIFHWGHM. Furthermore, we applied the proposed operators to the MCGDM problem and developed a new MCGDM approach. The characteristics of this new approach are that: (1 it is suitable for making a decision under the NIFN environment and it is more reasonable for aggregating the normal distribution data; (2 it utilizes Hamacher operation to provide an effective and powerful MCGDM algorithm and to make more reliable and more flexible decisions under the NIFN circumstance; (3 it uses the Heronian mean operator to deal with interrelations between the attributes or input arguments, and it does not bring about repeated calculation. Therefore, the proposed method can describe the interaction of the different criteria or input arguments and offer some reasonable and reliable MCGDM aggregation operators

  17. Expression regulation of design process gene in product design

    DEFF Research Database (Denmark)

    Li, Bo; Fang, Lusheng; Li, Bo

    2011-01-01

    To improve the design process efficiency, this paper proposes the principle and methodology that design process gene controls the characteristics of design process under the framework of design process reuse and optimization based on design process gene. First, the concept of design process gene...... is proposed and analyzed, as well as its three categories i.e., the operator gene, the structural gene and the regulator gene. Second, the trigger mechanism that design objectives and constraints trigger the operator gene is constructed. Third, the expression principle of structural gene is analyzed...... with the example of design management gene. Last, the regulation mode that the regulator gene regulates the expression of the structural gene is established and it is illustrated by taking the design process management gene as an example. © (2011) Trans Tech Publications....

  18. Asynchronous Operators of Sequential Logic Venjunction & Sequention

    CERN Document Server

    Vasyukevich, Vadim

    2011-01-01

    This book is dedicated to new mathematical instruments assigned for logical modeling of the memory of digital devices. The case in point is logic-dynamical operation named venjunction and venjunctive function as well as sequention and sequentional function. Venjunction and sequention operate within the framework of sequential logic. In a form of the corresponding equations, they organically fit analytical expressions of Boolean algebra. Thus, a sort of symbiosis is formed using elements of asynchronous sequential logic on the one hand and combinational logic on the other hand. So, asynchronous

  19. Hybrid Multidimensional Relational and Link Analytical Knowledge Discovery for Law Enforcement

    Energy Technology Data Exchange (ETDEWEB)

    Joslyn, Cliff A.; Gillen, David S.; Burke, John S.; Critchlow, Terence J.; Damante, Matt; Fernandes, Robert

    2008-08-01

    The challenges facing the Department of Homeland Security (DHS) require not only multi-dimensional, but also multi-scale data analysis. In particular, the ability to seamlessly move from summary information, such as trends, into detailed analysis of individual entities, while critical for law enforcement, typically requires manually transferring information among multiple tools. Such time-consuming and error prone processes significantly hamper the analysts' ability to quickly explore data and identify threats. As part of a DHS Science and Technology effort, we have been developing and deploying for Immigration and Customs Enforcement the CubeLink system integrating information between relational data cubes and link analytical semantic graphs. In this paper we describe CubeLink in terms of the underlying components, their integration, and the formal mapping from multidimensional data analysis into link analysis. In so doing, we provide a formal basis for one particular form of automatic schema-ontology mapping from OLAP data cubes to semantic graphs databases, and point the way towards future ``intelligent'' OLAP data cubes equipped with meta-data about their dimensional typing.

  20. Operator bases, S-matrices, and their partition functions

    Science.gov (United States)

    Henning, Brian; Lu, Xiaochuan; Melia, Tom; Murayama, Hitoshi

    2017-10-01

    Relativistic quantum systems that admit scattering experiments are quantitatively described by effective field theories, where S-matrix kinematics and symmetry considerations are encoded in the operator spectrum of the EFT. In this paper we use the S-matrix to derive the structure of the EFT operator basis, providing complementary descriptions in (i) position space utilizing the conformal algebra and cohomology and (ii) momentum space via an algebraic formulation in terms of a ring of momenta with kinematics implemented as an ideal. These frameworks systematically handle redundancies associated with equations of motion (on-shell) and integration by parts (momentum conservation). We introduce a partition function, termed the Hilbert series, to enumerate the operator basis — correspondingly, the S-matrix — and derive a matrix integral expression to compute the Hilbert series. The expression is general, easily applied in any spacetime dimension, with arbitrary field content and (linearly realized) symmetries. In addition to counting, we discuss construction of the basis. Simple algorithms follow from the algebraic formulation in momentum space. We explicitly compute the basis for operators involving up to n = 5 scalar fields. This construction universally applies to fields with spin, since the operator basis for scalars encodes the momentum dependence of n-point amplitudes. We discuss in detail the operator basis for non-linearly realized symmetries. In the presence of massless particles, there is freedom to impose additional structure on the S- matrix in the form of soft limits. The most na¨ıve implementation for massless scalars leads to the operator basis for pions, which we confirm using the standard CCWZ formulation for non-linear realizations. Although primarily discussed in the language of EFT, some of our results — conceptual and quantitative — may be of broader use in studying conformal field theories as well as the AdS/CFT correspondence.

  1. Infinite statistics and the SU(1, 1) phase operator

    International Nuclear Information System (INIS)

    Gerry, Christopher C

    2005-01-01

    A few years ago, Agarwal (1991 Phys. Rev. A 44 8398) showed that the Susskind-Glogower phase operators, expressible in terms of Bose operators, provide a realization of the algebra for particles obeying infinite statistics. In this paper we show that the SU(1, 1) phase operators, constructed in terms of the elements of the su(1, 1) Lie algebra, also provide a realization of the algebra for infinite statistics. There are many realizations of the su(1, 1) algebra in terms of single or multimode bose operators, three of which are discussed along with their corresponding phase states. The Susskind-Glogower phase operator is a special case of the SU(1, 1) phase operator associated with the Holstein-Primakoff realization of su(1, 1). (letter to the editor)

  2. On the uncertainty relations for vector-valued operators

    International Nuclear Information System (INIS)

    Chistyakov, A.L.

    1976-01-01

    In analogy with the expression for the Heisenberg incertainty principle in terms of dispersions by means of the Weyl inequality, in the case of one-dimensional quantum mechanical quantities, the principle for many-dimensional quantities can be expressed in terms of generalized dispersions and covariance matrices by means of inequalities similar to the Weyl unequality. The proofs of these inequalities are given in an abstract form, not only for the physical vector quantities, but also for arbitrary vector-valued operators with commuting self-adjoint components

  3. Bidirectional Modulation of Intrinsic Excitability in Rat Prelimbic Cortex Neuronal Ensembles and Non-Ensembles after Operant Learning.

    Science.gov (United States)

    Whitaker, Leslie R; Warren, Brandon L; Venniro, Marco; Harte, Tyler C; McPherson, Kylie B; Beidel, Jennifer; Bossert, Jennifer M; Shaham, Yavin; Bonci, Antonello; Hope, Bruce T

    2017-09-06

    Learned associations between environmental stimuli and rewards drive goal-directed learning and motivated behavior. These memories are thought to be encoded by alterations within specific patterns of sparsely distributed neurons called neuronal ensembles that are activated selectively by reward-predictive stimuli. Here, we use the Fos promoter to identify strongly activated neuronal ensembles in rat prelimbic cortex (PLC) and assess altered intrinsic excitability after 10 d of operant food self-administration training (1 h/d). First, we used the Daun02 inactivation procedure in male FosLacZ-transgenic rats to ablate selectively Fos-expressing PLC neurons that were active during operant food self-administration. Selective ablation of these neurons decreased food seeking. We then used male FosGFP-transgenic rats to assess selective alterations of intrinsic excitability in Fos-expressing neuronal ensembles (FosGFP + ) that were activated during food self-administration and compared these with alterations in less activated non-ensemble neurons (FosGFP - ). Using whole-cell recordings of layer V pyramidal neurons in an ex vivo brain slice preparation, we found that operant self-administration increased excitability of FosGFP + neurons and decreased excitability of FosGFP - neurons. Increased excitability of FosGFP + neurons was driven by increased steady-state input resistance. Decreased excitability of FosGFP - neurons was driven by increased contribution of small-conductance calcium-activated potassium (SK) channels. Injections of the specific SK channel antagonist apamin into PLC increased Fos expression but had no effect on food seeking. Overall, operant learning increased intrinsic excitability of PLC Fos-expressing neuronal ensembles that play a role in food seeking but decreased intrinsic excitability of Fos - non-ensembles. SIGNIFICANCE STATEMENT Prefrontal cortex activity plays a critical role in operant learning, but the underlying cellular mechanisms are

  4. Factorizable S-matrix and symmetry operator with toroidal rapidity values

    International Nuclear Information System (INIS)

    Hu Zhanning; Hou Boyu

    1992-01-01

    The factorizable S-matrix was constructed and the symmetry operator which commutes with the S-metric and has a new form of 'co-product', the elements of which depend on the parameters defining the toroidal rapidity surface. By defining a new operator which commutes with the symmetry operator the Yang-Baxter equation can be obtained. Finally, the relation between the broken Z N -symmetric model and the chiral Potts model was expressed explicitly in the self-dual genus zero limit

  5. Instanton Operators and the Higgs Branch at Infinite Coupling

    CERN Document Server

    Cremonesi, Stefano; Hanany, Amihay; Mekareeya, Noppadol

    2017-01-01

    The richness of 5d $\\mathcal{N}=1$ theories with a UV fixed point at infinite coupling is due to the existence of local disorder operators known as instanton operators. By considering the Higgs branch of $SU(2)$ gauge theories with $N_f \\leq 7$ flavours at finite and infinite coupling, we write down the explicit chiral ring relations between instanton operators, the glueball superfield and mesons. Exciting phenomena appear at infinite coupling: the glueball superfield is no longer nilpotent and the classical chiral ring relations are quantum corrected by instanton operators bilinears. We also find expressions for the dressing of instanton operators of arbitrary charge. The same analysis is performed for $USp(2k)$ with an antisymmetric hypermultiplet and pure $SU(N)$ gauge theories.

  6. Instanton operators and the Higgs branch at infinite coupling

    Energy Technology Data Exchange (ETDEWEB)

    Cremonesi, Stefano [Department of Mathematics, King’s College London,The Strand, London WC2R 2LS (United Kingdom); Ferlito, Giulia; Hanany, Amihay [Theoretical Physics Group, Imperial College London,Prince Consort Road, London, SW7 2AZ (United Kingdom); Mekareeya, Noppadol [Theory Division, Physics Department, CERN,CH-1211, Geneva 23 (Switzerland)

    2017-04-10

    The richness of 5d N=1 theories with a UV fixed point at infinite coupling is due to the existence of local disorder operators known as instanton operators. By considering the Higgs branch of SU(2) gauge theories with N{sub f}≤7 flavours at finite and infinite coupling, we write down the explicit chiral ring relations between instanton operators, the glueball superfield and mesons. Exciting phenomena appear at infinite coupling: the glueball superfield is no longer nilpotent and the classical chiral ring relations are quantum corrected by instanton operators bilinears. We also find expressions for the dressing of instanton operators of arbitrary charge. The same analysis is performed for USp(2k) with an antisymmetric hypermultiplet and pure SU(N) gauge theories.

  7. The noise analysis and the BWR operation map

    International Nuclear Information System (INIS)

    Blazquez, J.; Ballestrin, J.

    1996-01-01

    An analytical expression for the Decay Ratio is obtained: DR = exp(-bW / P 1/2 ). The physics behind is also explained. It applies to a commercial BWR Operation Map, on the vicinity of the power instability. This functional form seems fitting to the structure of the Operation map. The power P and the coolant flow are measured straightforward; the Decay Ratio is obtained by neutron noise analysis techniques. The parameter b, depending on the void reactivity coefficient, is then calculated on line during the Reactor Operation. New DR value is now predicted for each new displacement on the Map, so unexpected instability events are more likely avoided. (authors)

  8. Word aligned bitmap compression method, data structure, and apparatus

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Kesheng; Shoshani, Arie; Otoo, Ekow

    2004-12-14

    The Word-Aligned Hybrid (WAH) bitmap compression method and data structure is a relatively efficient method for searching and performing logical, counting, and pattern location operations upon large datasets. The technique is comprised of a data structure and methods that are optimized for computational efficiency by using the WAH compression method, which typically takes advantage of the target computing system's native word length. WAH is particularly apropos to infrequently varying databases, including those found in the on-line analytical processing (OLAP) industry, due to the increased computational efficiency of the WAH compressed bitmap index. Some commercial database products already include some version of a bitmap index, which could possibly be replaced by the WAH bitmap compression techniques for potentially increased operation speed, as well as increased efficiencies in constructing compressed bitmaps. Combined together, this technique may be particularly useful for real-time business intelligence. Additional WAH applications may include scientific modeling, such as climate and combustion simulations, to minimize search time for analysis and subsequent data visualization.

  9. SQL and Multidimensional Data

    Directory of Open Access Journals (Sweden)

    Mihaela MUNTEAN

    2006-01-01

    Full Text Available Using SQL you can manipulate multidimensional data and extract that data into a relational table. There are many PL/SQL packages that you can use directly in SQL*Plus or indirectly in Analytic Workspace Manager and OLAP Worksheet. In this article I discussed about some methods that you can use for manipulating and extracting multidimensional data.

  10. A general diagrammatic algorithm for contraction and subsequent simplification of second-quantized expressions.

    Science.gov (United States)

    Bochevarov, Arteum D; Sherrill, C David

    2004-08-22

    We present a general computer algorithm to contract an arbitrary number of second-quantized expressions and simplify the obtained analytical result. The functions that perform these operations are a part of the program Nostromo which facilitates the handling and analysis of the complicated mathematical formulas which are often encountered in modern quantum-chemical models. In contrast to existing codes of this kind, Nostromo is based solely on the Goldstone-diagrammatic representation of algebraic expressions in Fock space and has capabilities to work with operators as well as scalars. Each Goldstone diagram is internally represented by a line of text which is easy to interpret and transform. The calculation of matrix elements does not exploit Wick's theorem in a direct way, but uses diagrammatic techniques to produce only nonzero terms. The identification of equivalent expressions and their subsequent factorization in the final result is performed easily by analyzing the topological structure of the diagrammatic expressions. (c) 2004 American Institute of Physics

  11. OPERATIVE GROUP: EDUCATIONAL PRACTICE AS AN EXPRESSION FOR SELF-CARE IN DIABETES MELLITUS TYPE 2

    Directory of Open Access Journals (Sweden)

    Mariana Almeida Maia

    2013-12-01

    Full Text Available The goal is to understand the views of users with type 2 diabetes about their participation in the operating groups and the impact of self-care practices. This is a qualitative descriptive- exploratory held in three basic health units of the sanitary district east of Belo Horizonte and involved the participation of 18 users in 2011. The speeches of the users were analyzed based on content analysis, identifying the categories: exchange of experience, education for self- care, assessment of user participation in the operative groups, Feelings and links between professionals and users. It was noted that the operational groups provided the construction of knowledge through listening, reflection and questioning of reality where the user identified the importance of knowledge about diet, physical activity and treatment. We found that health actions implemented through the operational groups encourage users to think about your lifestyle, characterized as a tool in health education from the perspective of promotion, prevention and control.

  12. Detecting parathyroid adenoma using technetium-99m tetrofosmin: comparison with P-glycoprotein and multidrug resistance related protein expression--a preliminary report

    International Nuclear Information System (INIS)

    Shiau, Y.C.; Tsai, S.C.; Wang, J.J.; Ho, S.T.; Kao, A.

    2002-01-01

    The aim of this study was to investigate the relationships among technetium-99m tetrofosmin (Tc-TF) accumulation in parathyroid adenoma and the expression of P-glycoprotein (Pgp) or multidrug resistance related protein (MRP). Before operation, 33 patients with parathyroid adenomas (larger than 1.5 gm) were studied with parathyroid scintigraphy 10 minutes and 2 hours after intravenous injection of Tc-TF before operation. Immunohistochemical analyses (IHA) were performed on multiple nonconsecutive sections of operative parathyroid specimens to detect Pgp or MRP expression. According to the results of IHA, the 33 parathyroid adenomas were separated into four groups: (1) 2 adenomas with both positive Pgp and positive MRP expression, (2) 1 adenomas with positive Pgp but negative MRP expression, (3) 2 adenomas with negative Pgp but positive MRP expression, and (4) 28 adenomas with both negative Pgp and negative MRP expression. All of 28 adenomas in the group 4 could be detected by Tc-TF parathyroid imaging. All of 5 adenomas in the groups 1 to 3 could not be detected by TcTF parathyroid imaging (p < 0.05). Not only the size of parathyroid adenomas, but also significant Pgp or MRP expression limited the sensitivity of Tc-TF parathyroid imaging to localize parathyroid adenomas before operation

  13. Projection operators and supplementary conditions for superfields with an arbitrary spin

    International Nuclear Information System (INIS)

    Sokatchev, E.

    1975-01-01

    It is shown that a superfield with an external spin j and a nonzero mass contains four non reducible representations of supersymmetry algebra. A general method is proposed for the evolution the representations out of the superfield by using projection operators, derived from Casimir operators. This expansion is also expressed in terms of additional differential conditions

  14. Schroedinger operators - geometric estimates in terms of the occupation time

    International Nuclear Information System (INIS)

    Demuth, M.; Kirsch, W.; McGillivray, I.

    1995-01-01

    The difference of Schroedinger and Dirichlet semigroups is expressed in terms of the Laplace transform of the Brownian motion occupation time. This implies quantitative upper and lower bounds for the operator norms of the corresponding resolvent differences. One spectral theoretical consequence is an estimate for the eigenfunction for a Schroedinger operator in a ball where the potential is given as a cone indicator function. 12 refs

  15. Manual of a suite of computer codes, EXPRESS (EXact PREparedness Supporting System)

    International Nuclear Information System (INIS)

    Chino, Masamichi

    1992-06-01

    The emergency response supporting system EXPRESS (EXact PREparedness Supporting System) is constructed in JAERI for low cost engineering work stations under the UNIX operation. The purpose of this system is real-time predictions of affected areas due to radioactivities discharged into atmosphere from nuclear facilities. The computational models in EXPRESS are the mass-consistent wind field model EXPRESS-I and the particle dispersion model EXPRESS-II for atmospheric dispersions. In order to attain the quick response even when the codes are used in a small-scale computer, a high-speed iteration method MILUCR (Modified Incomplete Linear Unitary Conjugate Residual) is applied to EXPRESS-I and kernel density method is to EXPRESS-II. This manual describes the model configurations, code structures, related files, namelists and sample outputs of EXPRESS-I and -II. (author)

  16. Classification of emotions by multivariate analysis and individual differences of nuclear power plant operators` emotion

    Energy Technology Data Exchange (ETDEWEB)

    Hasegawa, Naoko; Yoshimura, Seiichi [Central Research Inst. of Electric Power Industry, Tokyo (Japan)

    1999-03-01

    The purpose of this study is the development of a simulation model which expresses operators` emotion under plant emergency. This report shows the classification of emotions by multivariate analysis and investigation results conducted to clarify individual differences of activated emotion influenced by personal traits. Although a former investigation was conducted to classify emotions into five basic emotions proposed by Johnson-Laird, the basic emotions was not based on real data. For the development of more realistic and accurate simulation model, it is necessary to recognize basic emotion and to classify emotions into them. As a result of analysis by qualification method 3 and cluster analysis, four basic clusters were clarified, i.e., Emotion expressed towards objects, Emotion affected by objects, Pleasant emotion, and Surprise. Moreover, 51 emotions were ranked in the order according to their similarities in each cluster. An investigation was conducted to clarify individual differences in emotion process using 87 plant operators. The results showed the differences of emotion depending on the existence of operators` foresight, cognitive style, experience in operation, and consciousness of attribution to an operating team. For example, operators with low self-efficacy, short experience or low consciousness of attribution to a team, feel more intensive emotion under plant emergency and more affected by severe plant conditions. The model which can express individual differences will be developed utilizing and converting these data hereafter. (author)

  17. Classification of emotions by multivariate analysis and individual differences of nuclear power plant operators' emotion

    International Nuclear Information System (INIS)

    Hasegawa, Naoko; Yoshimura, Seiichi

    1999-01-01

    The purpose of this study is the development of a simulation model which expresses operators' emotion under plant emergency. This report shows the classification of emotions by multivariate analysis and investigation results conducted to clarify individual differences of activated emotion influenced by personal traits. Although a former investigation was conducted to classify emotions into five basic emotions proposed by Johnson-Laird, the basic emotions was not based on real data. For the development of more realistic and accurate simulation model, it is necessary to recognize basic emotion and to classify emotions into them. As a result of analysis by qualification method 3 and cluster analysis, four basic clusters were clarified, i.e., Emotion expressed towards objects, Emotion affected by objects, Pleasant emotion, and Surprise. Moreover, 51 emotions were ranked in the order according to their similarities in each cluster. An investigation was conducted to clarify individual differences in emotion process using 87 plant operators. The results showed the differences of emotion depending on the existence of operators' foresight, cognitive style, experience in operation, and consciousness of attribution to an operating team. For example, operators with low self-efficacy, short experience or low consciousness of attribution to a team, feel more intensive emotion under plant emergency and more affected by severe plant conditions. The model which can express individual differences will be developed utilizing and converting these data hereafter. (author)

  18. Perceptually Valid Facial Expressions for Character-Based Applications

    Directory of Open Access Journals (Sweden)

    Ali Arya

    2009-01-01

    Full Text Available This paper addresses the problem of creating facial expression of mixed emotions in a perceptually valid way. The research has been done in the context of a “game-like” health and education applications aimed at studying social competency and facial expression awareness in autistic children as well as native language learning, but the results can be applied to many other applications such as games with need for dynamic facial expressions or tools for automating the creation of facial animations. Most existing methods for creating facial expressions of mixed emotions use operations like averaging to create the combined effect of two universal emotions. Such methods may be mathematically justifiable but are not necessarily valid from a perceptual point of view. The research reported here starts by user experiments aiming at understanding how people combine facial actions to express mixed emotions, and how the viewers perceive a set of facial actions in terms of underlying emotions. Using the results of these experiments and a three-dimensional emotion model, we associate facial actions to dimensions and regions in the emotion space, and create a facial expression based on the location of the mixed emotion in the three-dimensional space. We call these regionalized facial actions “facial expression units.”

  19. Development of heart failure is independent of K+ channel-interacting protein 2 expression

    Science.gov (United States)

    Speerschneider, Tobias; Grubb, Søren; Metoska, Artina; Olesen, Søren-Peter; Calloe, Kirstine; Thomsen, Morten B

    2013-01-01

    Abnormal ventricular repolarization in ion channelopathies and heart disease is a major cause of ventricular arrhythmias and sudden cardiac death. K+ channel-interacting protein 2 (KChIP2) expression is significantly reduced in human heart failure (HF), contributing to a loss of the transient outward K+ current (Ito). We aim to investigate the possible significance of a changed KChIP2 expression on the development of HF and proarrhythmia. Transverse aortic constrictions (TAC) and sham operations were performed in wild-type (WT) and KChIP2−/− mice. Echocardiography was performed before and every 2 weeks after the operation. Ten weeks post-surgery, surface ECG was recorded and we paced the heart in vivo to induce arrhythmias. Afterwards, tissue from the left ventricle was used for immunoblotting. Time courses of HF development were comparable in TAC-operated WT and KChIP2−/− mice. Ventricular protein expression of KChIP2 was reduced by 70% after 10 weeks TAC in WT mice. The amplitudes of the J and T waves were enlarged in KChIP2−/− control mice. Ventricular effective refractory period, RR, QRS and QT intervals were longer in mice with HF compared to sham-operated mice of either genotype. Pacing-induced ventricular tachycardia (VT) was observed in 5/10 sham-operated WT mice compared with 2/10 HF WT mice with HF. Interestingly, and contrary to previously published data, sham-operated KChIP2−/− mice were resistant to pacing-induced VT resulting in only 1/10 inducible mice. KChIP2−/− with HF mice had similar low vulnerability to inducible VT (1/9). Our results suggest that although KChIP2 is downregulated in HF, it is not orchestrating the development of HF. Moreover, KChIP2 affects ventricular repolarization and lowers arrhythmia susceptibility. Hence, downregulation of KChIP2 expression in HF may be antiarrhythmic in mice via reduction of the fast transient outward K+ current. PMID:24099801

  20. RANK and RANK ligand expression in primary human osteosarcoma

    Directory of Open Access Journals (Sweden)

    Daniel Branstetter

    2015-09-01

    Our results demonstrate RANKL expression was observed in the tumor element in 68% of human OS using IHC. However, the staining intensity was relatively low and only 37% (29/79 of samples exhibited≥10% RANKL positive tumor cells. RANK expression was not observed in OS tumor cells. In contrast, RANK expression was clearly observed in other cells within OS samples, including the myeloid osteoclast precursor compartment, osteoclasts and in giant osteoclast cells. The intensity and frequency of RANKL and RANK staining in OS samples were substantially less than that observed in GCTB samples. The observation that RANKL is expressed in OS cells themselves suggests that these tumors may mediate an osteoclastic response, and anti-RANKL therapy may potentially be protective against bone pathologies in OS. However, the absence of RANK expression in primary human OS cells suggests that any autocrine RANKL/RANK signaling in human OS tumor cells is not operative, and anti-RANKL therapy would not directly affect the tumor.

  1. Cellular MYCro economics: Balancing MYC function with MYC expression.

    Science.gov (United States)

    Levens, David

    2013-11-01

    The expression levels of the MYC oncoprotein have long been recognized to be associated with the outputs of major cellular processes including proliferation, cell growth, apoptosis, differentiation, and metabolism. Therefore, to understand how MYC operates, it is important to define quantitatively the relationship between MYC input and expression output for its targets as well as the higher-order relationships between the expression levels of subnetwork components and the flow of information and materials through those networks. Two different views of MYC are considered, first as a molecular microeconomic manager orchestrating specific positive and negative responses at individual promoters in collaboration with other transcription and chromatin components, and second, as a macroeconomic czar imposing an overarching rule onto all active genes. In either case, c-myc promoter output requires multiple inputs and exploits diverse mechanisms to tune expression to the appropriate levels relative to the thresholds of expression that separate health and disease.

  2. Distinct Calcium Signaling Pathways Regulate Calmodulin Gene Expression in Tobacco1

    Science.gov (United States)

    van der Luit, Arnold H.; Olivari, Claudio; Haley, Ann; Knight, Marc R.; Trewavas, Anthony J.

    1999-01-01

    Cold shock and wind stimuli initiate Ca2+ transients in transgenic tobacco (Nicotiana plumbaginifolia) seedlings (named MAQ 2.4) containing cytoplasmic aequorin. To investigate whether these stimuli initiate Ca2+ pathways that are spatially distinct, stress-induced nuclear and cytoplasmic Ca2+ transients and the expression of a stress-induced calmodulin gene were compared. Tobacco seedlings were transformed with a construct that encodes a fusion protein between nucleoplasmin (a major oocyte nuclear protein) and aequorin. Immunocytochemical evidence indicated targeting of the fusion protein to the nucleus in these plants, which were named MAQ 7.11. Comparison between MAQ 7.11 and MAQ 2.4 seedlings confirmed that wind stimuli and cold shock invoke separate Ca2+ signaling pathways. Partial cDNAs encoding two tobacco calmodulin genes, NpCaM-1 and NpCaM-2, were identified and shown to have distinct nucleotide sequences that encode identical polypeptides. Expression of NpCaM-1, but not NpCaM-2, responded to wind and cold shock stimulation. Comparison of the Ca2+ dynamics with NpCaM-1 expression after stimulation suggested that wind-induced NpCaM-1 expression is regulated by a Ca2+ signaling pathway operational predominantly in the nucleus. In contrast, expression of NpCaM-1 in response to cold shock is regulated by a pathway operational predominantly in the cytoplasm. PMID:10557218

  3. 78 FR 2483 - Ohio Terminal Railway Company-Operation Exemption-Hannibal Real Estate, LLC

    Science.gov (United States)

    2013-01-11

    ... Railway Company--Operation Exemption--Hannibal Real Estate, LLC Ohio Terminal Railway Company (OTRC),\\1\\ a... near Hannibal, in Monroe County, Ohio (the Line), pursuant to an operating agreement with Hannibal Real Estate, LLC (Hannibal). \\1\\ OTRC is a wholly owned, corporate subsidiary of Carload Express, Inc. (CEI...

  4. Structure of Pioncare covariant tensor operators in quantum mechanical models

    International Nuclear Information System (INIS)

    Polyzou, W.N.; Klink, W.H.

    1988-01-01

    The structure of operators that transform covariantly in Poincare invariant quantum mechanical models is analyzed. These operators are shown to have an interaction dependence that comes from the geometry of the Poincare group. The operators can be expressed in terms of matrix elements in a complete set of eigenstates of the mass and spin operators associated with the dynamical representation of the Poincare group. The matrix elements are factored into geometrical coefficients (Clebsch--Gordan coefficients for the Poincare group) and invariant matrix elements. The geometrical coefficients are fixed by the transformation properties of the operator and the eigenvalue spectrum of the mass and spin. The invariant matrix elements, which distinguish between different operators with the same transformation properties, are given in terms of a set of invariant form factors. copyright 1988 Academic Press, Inc

  5. Development of heart failure is independent of K+ channel-interacting protein 2 expression

    DEFF Research Database (Denmark)

    Speerschneider, Tobias; Grubb, Søren; Metoska, Artina

    2013-01-01

    of the transient outward K(+) current (Ito). We aim to investigate the possible significance of a changed KChIP2 expression on the development of HF and proarrhythmia. Transverse aortic constrictions (TAC) and sham operations were performed in wild-type (WT) and KChIP2(-/-) mice. Echocardiography was performed......(-/-) mice. Ventricular protein expression of KChIP2 was reduced by 70% after 10 weeks TAC in WT mice. The amplitudes of the J and T waves were enlarged in KChIP2(-/-) control mice. Ventricular effective refractory period, RR, QRS and QT intervals were longer in mice with HF compared to sham-operated mice...... of either genotype. Pacing-induced ventricular tachycardia (VT) was observed in 5/10 sham-operated WT mice compared with 2/10 HF WT mice with HF. Interestingly, and contrary to previously published data, sham-operated KChIP2(-/-) mice were resistant to pacing-induced VT resulting in only 1/10 inducible mice...

  6. Intrinsic-normal-ordered vertex operators from the multiloop N-tachyon amplitude

    International Nuclear Information System (INIS)

    Aldazabal, G.; Nunez, C.; Bonini, M.; Iengo, R.

    1987-09-01

    We construct vertex operators for arbitrary mass level states of the closed bosonic string. Starting from a generalization of the Koba-Nielsen amplitude which is suitable for an arbitrary genus Riemann surface, we read the vertex operators from the residues of the poles for the intermediate states. Since the original expression is metric independent and normal ordered without the need of inventing any regularization scheme, our vertex operators also possess these properties. We discuss their general features. (author). 17 refs

  7. On the quantum Landau collision operator and electron collisions in dense plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Daligault, Jérôme, E-mail: daligaul@lanl.gov [Theoretical Division, Los Alamos National Laboratory, Los Alamos, New Mexico 87545 (United States)

    2016-03-15

    The quantum Landau collision operator, which extends the widely used Landau/Fokker-Planck collision operator to include quantum statistical effects, is discussed. The quantum extension can serve as a reference model for including electron collisions in non-equilibrium dense plasmas, in which the quantum nature of electrons cannot be neglected. In this paper, the properties of the Landau collision operator that have been useful in traditional plasma kinetic theory and plasma transport theory are extended to the quantum case. We outline basic properties in connection with the conservation laws, the H-theorem, and the global and local equilibrium distributions. We discuss the Fokker-Planck form of the operator in terms of three potentials that extend the usual two Rosenbluth potentials. We establish practical closed-form expressions for these potentials under local thermal equilibrium conditions in terms of Fermi-Dirac and Bose-Einstein integrals. We study the properties of linearized quantum Landau operator, and extend two popular approximations used in plasma physics to include collisions in kinetic simulations. We apply the quantum Landau operator to the classic test-particle problem to illustrate the physical effects embodied in the quantum extension. We present useful closed-form expressions for the electron-ion momentum and energy transfer rates. Throughout the paper, similarities and differences between the quantum and classical Landau collision operators are emphasized.

  8. On the quantum Landau collision operator and electron collisions in dense plasmas

    Science.gov (United States)

    Daligault, Jérôme

    2016-03-01

    The quantum Landau collision operator, which extends the widely used Landau/Fokker-Planck collision operator to include quantum statistical effects, is discussed. The quantum extension can serve as a reference model for including electron collisions in non-equilibrium dense plasmas, in which the quantum nature of electrons cannot be neglected. In this paper, the properties of the Landau collision operator that have been useful in traditional plasma kinetic theory and plasma transport theory are extended to the quantum case. We outline basic properties in connection with the conservation laws, the H-theorem, and the global and local equilibrium distributions. We discuss the Fokker-Planck form of the operator in terms of three potentials that extend the usual two Rosenbluth potentials. We establish practical closed-form expressions for these potentials under local thermal equilibrium conditions in terms of Fermi-Dirac and Bose-Einstein integrals. We study the properties of linearized quantum Landau operator, and extend two popular approximations used in plasma physics to include collisions in kinetic simulations. We apply the quantum Landau operator to the classic test-particle problem to illustrate the physical effects embodied in the quantum extension. We present useful closed-form expressions for the electron-ion momentum and energy transfer rates. Throughout the paper, similarities and differences between the quantum and classical Landau collision operators are emphasized.

  9. On Recursion Operator of the q -KP Hierarchy

    International Nuclear Information System (INIS)

    Tian Ke-Lei; Zhu Xiao-Ming; He Jing-Song

    2016-01-01

    It is the aim of the present article to give a general expression of flow equations of the q-KP hierarchy. The distinct difference between the q-KP hierarchy and the KP hierarchy is due to q-binomial and the action of q-shift operator θ, which originates from the Leibnitz rule of the quantum calculus. We further show that the n-reduction leads to a recursive scheme for these flow equations. The recursion operator for the flow equations of the q-KP hierarchy under the n-reduction is also derived. (paper)

  10. The vertex Zagreb indices of some graph operations

    Directory of Open Access Journals (Sweden)

    N. De

    2016-12-01

    Full Text Available Recently, Tavakoli et al. introduced a new version of Zagreb indices, named as vertex Zagreb indices. In this paper explicit expressions of different graphs operations of vertex Zagreb indices are presented and also as an application, explicit formulas for vertex Zagreb indices of some chemical graphs are obtained.

  11. Automatic Control of Gene Expression in Mammalian Cells.

    Science.gov (United States)

    Fracassi, Chiara; Postiglione, Lorena; Fiore, Gianfranco; di Bernardo, Diego

    2016-04-15

    Automatic control of gene expression in living cells is paramount importance to characterize both endogenous gene regulatory networks and synthetic circuits. In addition, such a technology can be used to maintain the expression of synthetic circuit components in an optimal range in order to ensure reliable performance. Here we present a microfluidics-based method to automatically control gene expression from the tetracycline-inducible promoter in mammalian cells in real time. Our approach is based on the negative-feedback control engineering paradigm. We validated our method in a monoclonal population of cells constitutively expressing a fluorescent reporter protein (d2EYFP) downstream of a minimal CMV promoter with seven tet-responsive operator motifs (CMV-TET). These cells also constitutively express the tetracycline transactivator protein (tTA). In cells grown in standard growth medium, tTA is able to bind the CMV-TET promoter, causing d2EYFP to be maximally expressed. Upon addition of tetracycline to the culture medium, tTA detaches from the CMV-TET promoter, thus preventing d2EYFP expression. We tested two different model-independent control algorithms (relay and proportional-integral (PI)) to force a monoclonal population of cells to express an intermediate level of d2EYFP equal to 50% of its maximum expression level for up to 3500 min. The control input is either tetracycline-rich or standard growth medium. We demonstrated that both the relay and PI controllers can regulate gene expression at the desired level, despite oscillations (dampened in the case of the PI controller) around the chosen set point.

  12. Development of datamining software for the city water supply company

    Science.gov (United States)

    Orlinskaya, O. G.; Boiko, E. V.

    2018-05-01

    The article considers issues of datamining software development for city water supply enterprises. Main stages of OLAP and datamining systems development are proposed. The system will allow water supply companies analyse accumulated data. Accordingly, improving the quality of data analysis would improve the manageability of the company and help to make the right managerial decisions by executives of various levels.

  13. Code on the safety of nuclear research reactors: Operation

    International Nuclear Information System (INIS)

    1992-01-01

    The purpose of this publication is to provide the essential requirements and recommendations for the safe operation of research reactors, with emphasis on the supervisory and managerial aspects. However, the publication also provides some guidance and information on topics concerning all the organizations involved in operation. These objectives are expressed in terms of requirements and recommendations for the safe operation of research reactors. Emphasis is placed on the safety requirements that shall be met rather than on the ways in which they can be met. The requirements and recommendations may form the foundation necessary for a Member State to develop regulations and safety criteria for its research reactor programme.

  14. A differential operator for integrating one-loop scattering equations

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Tianheng [Department of Physics, Nanjing University,Nanjing, Jiangsu Province (China); Chen, Gang [Department of Physics, Zhejiang Normal University,Jinhua, Zhejiang Province (China); Department of Physics and Astronomy, Uppsala University,Uppsala (Sweden); Department of Physics, Nanjing University,Nanjing, Jiangsu Province (China); Cheung, Yeuk-Kwan E. [Department of Physics, Nanjing University,Nanjing, Jiangsu Province (China); Xu, Feng [Weavi Corporation Limited, Nanjing,Jiangsu Province (China)

    2017-01-09

    We propose a differential operator for computing the residues associated with a class of meromorphic n-forms that frequently appear in the Cachazo-He-Yuan form of the scattering amplitudes. This differential operator is conjectured to be uniquely determined by the local duality theorem and the intersection number of the divisors in the n-form. We use the operator to evaluate the one-loop integrand of Yang-Mills theory from their generalized CHY formulae. The method can reduce the complexity of the calculation. In addition, the expression for the 1-loop four-point Yang-Mills integrand obtained in our approach has a clear correspondence with the Q-cut results.

  15. Three-loop evolution equation for flavor-nonsinglet operators in off-forward kinematics

    Energy Technology Data Exchange (ETDEWEB)

    Braun, V.M.; Strohmaier, M. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Manashov, A.N. [Regensburg Univ. (Germany). Inst. fuer Theoretische Physik; Hamburg Univ. (Germany). 1. Inst. fuer Theoretische Physik; Moch, S. [Hamburg Univ. (Germany). 1. Inst. fuer Theoretische Physik

    2017-03-15

    Using the approach based on conformal symmetry we calculate the three-loop (NNLO) contribution to the evolution equation for flavor-nonsinglet leading twist operators in the MS scheme. The explicit expression for the three-loop kernel is derived for the corresponding light-ray operator in coordinate space. The expansion in local operators is performed and explicit results are given for the matrix of the anomalous dimensions for the operators up to seven covariant derivatives. The results are directly applicable to the renormalization of the pion light-cone distribution amplitude and flavor-nonsinglet generalized parton distributions.

  16. A Summary of the Rendezvous, Proximity Operations, Docking, and Undocking (RPODU) Lessons Learned from the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) Demonstration System Mission

    Science.gov (United States)

    Dennehy, Cornelius J.; Carpenter, James R.

    2011-01-01

    The Guidance, Navigation, and Control (GN&C) Technical Discipline Team (TDT) sponsored Dr. J. Russell Carpenter, a Navigation and Rendezvous Subject Matter Expert (SME) from NASA's Goddard Space Flight Center (GSFC), to provide support to the Defense Advanced Research Project Agency (DARPA) Orbital Express (OE) rendezvous and docking flight test that was conducted in 2007. When that DARPA OE mission was completed, Mr. Neil Dennehy, NASA Technical Fellow for GN&C, requested Dr. Carpenter document his findings (lessons learned) and recommendations for future rendezvous missions resulting from his OE support experience. This report captures lessons specifically from anomalies that occurred during one of OE's unmated operations.

  17. Two-spinor description of massive particles and relativistic spin projection operators

    Science.gov (United States)

    Isaev, A. P.; Podoinitsyn, M. A.

    2018-04-01

    On the basis of the Wigner unitary representations of the covering group ISL (2 , C) of the Poincaré group, we obtain spin-tensor wave functions of free massive particles with arbitrary spin. The wave functions automatically satisfy the Dirac-Pauli-Fierz equations. In the framework of the two-spinor formalism we construct spin-vectors of polarizations and obtain conditions that fix the corresponding relativistic spin projection operators (Behrends-Fronsdal projection operators). With the help of these conditions we find explicit expressions for relativistic spin projection operators for integer spins (Behrends-Fronsdal projection operators) and then find relativistic spin projection operators for half integer spins. These projection operators determine the numerators in the propagators of fields of relativistic particles. We deduce generalizations of the Behrends-Fronsdal projection operators for arbitrary space-time dimensions D > 2.

  18. INFORMATION ARCHITECTURE ANALYSIS USING BUSINESS INTELLIGENCE TOOLS BASED ON THE INFORMATION NEEDS OF EXECUTIVES

    Directory of Open Access Journals (Sweden)

    Fabricio Sobrosa Affeldt

    2013-08-01

    Full Text Available Devising an information architecture system that enables an organization to centralize information regarding its operational, managerial and strategic performance is one of the challenges currently facing information technology. The present study aimed to analyze an information architecture system developed using Business Intelligence (BI technology. The analysis was performed based on a questionnaire enquiring as to whether the information needs of executives were met during the process. A theoretical framework was applied consisting of information architecture and BI technology, using a case study methodology. Results indicated that the transaction processing systems studied did not meet the information needs of company executives. Information architecture using data warehousing, online analytical processing (OLAP tools and data mining may provide a more agile means of meeting these needs. However, some items must be included and others modified, in addition to improving the culture of information use by company executives.

  19. Maintenance Operations Degradation of Airfield Pavement Markings

    Science.gov (United States)

    2012-03-01

    DISTRIBUTION STATEMENT A. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED The views expressed in this article are those of the author and...DISTRIBUTION STATEMENT A. APPROVED FOR PUBLIC RELEASE; DISTRIBUTION UNLIMITED AFIT/GEM/ENV/12-M09 MAINTENANCE OPERATIONS DEGRADATION OF...placement, color, and style (Federal Aviation Adminstration (FAA), 2010). However, regulations and standards do not make good asset management plans

  20. On operator mixing in N=4 SYM

    International Nuclear Information System (INIS)

    Bianchi, Massimo; Eden, Burkhard; Rossi, Giancarlo; Stanev, Yassen S.

    2002-01-01

    We resolve the mixing of the scalar operators of naive dimension 4 belonging to the representation 20' of the SU(4) R-symmetry in N=4 SYM. We compute the order g 2 corrections to their anomalous dimensions and show the absence of instantonic contributions thereof. Ratios of the resulting expressions are irrational numbers, even in the large N limit where, however, we observe the expected decoupling of double-trace operators from single-trace ones. We briefly comment on the generalizations of our results required in order to make contact with the double scaling limit of the theory conjectured to be holographically dual to type IIB superstring on a pp-wave

  1. Renormalization and operator product expansion in theories with massless particles

    International Nuclear Information System (INIS)

    Anikin, S.A.; Smirnov, V.A.

    1985-01-01

    Renormalization procedure in theories including massless particles is presented. With the help of counterterm formalism the operator product expansion for arbitrary composite fields is derived. The coefficient functions are explicitly expressed in terms of certain Green's functions. (author)

  2. Automation-aided Task Loads Index based on the Automation Rate Reflecting the Effects on Human Operators in NPPs

    International Nuclear Information System (INIS)

    Lee, Seungmin; Seong, Poonghyun; Kim, Jonghyun

    2013-01-01

    Many researchers have found that a high automation rate does not guarantee high performance. Therefore, to reflect the effects of automation on human performance, a new estimation method of the automation rate that considers the effects of automation on human operators in nuclear power plants (NPPs) was suggested. These suggested measures express how much automation support human operators but it cannot express the change of human operators' workload, whether the human operators' workload is increased or decreased. Before considering automation rates, whether the adopted automation is good or bad might be estimated in advance. In this study, to estimate the appropriateness of automation according to the change of the human operators' task loads, automation-aided task loads index is suggested based on the concept of the suggested automation rate. To insure plant safety and efficiency on behalf of human operators, various automation systems have been installed in NPPs, and many works which were previously conducted by human operators can now be supported by computer-based operator aids. According to the characteristics of the automation types, the estimation method of the system automation and the cognitive automation rate were suggested. The proposed estimation method concentrates on the effects of introducing automation, so it directly express how much the automated system support human operators. Based on the suggested automation rates, the way to estimate how much the automated system can affect the human operators' cognitive task load is suggested in this study. When there is no automation, the calculated index is 1, and it means there is no change of human operators' task load

  3. Expression of classical mediators in hearts of rats with hepatic dysfunction.

    Science.gov (United States)

    Jarkovska, Dagmar; Bludovska, Monika; Mistrova, Eliska; Krizkova, Vera; Kotyzova, Dana; Kubikova, Tereza; Slavikova, Jana; Erek, Sumeyye Nur; Djordjevic, Aleksandar; Chottova Dvorakova, Magdalena

    2017-11-01

    Liver cirrhosis is associated with impairment of cardiovascular function including alterations of the heart innervation, humoral and nervous dysregulation, changes in systemic circulation and electrophysiological abnormalities. Choline acetyltransferase (ChAT), enzyme forming acetylcholine, tyrosine hydroxylase (TH), and dopamine-β-hydroxylase (DBH), enzymes participating in noradrenaline synthesis, are responsible for the production of classical neurotransmitters, and atrial natriuretic peptide (ANP) is produced by cardiomyocytes. The aim of this study was to evaluate the influence of experimentally induced hepatic dysfunction on the expression of proANP, ChAT, TH, and DBH in the heart. Hepatic dysfunction was induced by application of thioacetamide (TAA) or by ligation of bile duct. Biochemical parameters of hepatic injury and levels of peroxidation in the liver and heart were measured. Liver enzymes measured in the plasma were significantly elevated. Cardiac level of peroxidation was increased in operated but not TAA group animals. In the left atrium of operated rats, the expression of TH and DBH was lower, while expression of ChAT remained unchanged. In TAA group, no significant differences in the expression of the genes compared to controls were observed. Liver injury induced by ligation leads to an imbalance in the intracardiac innervation, which might impair nervous control of the heart.

  4. Study of patient satisfaction and self-expressed problems after emergency caesarean delivery under subarachnoid block

    Directory of Open Access Journals (Sweden)

    V R Hemanth Kumar

    2014-01-01

    Full Text Available Background and Aims: Subarachnoid block is one of the common modes of anaesthesia opted for emergency caesarean section, if the maternal and foetal conditions are favourable. Various factors influence the quality of care administered during the procedure. This questionnaire based study was undertaken to look for self-expressed problems in peri-operative period in patients undergoing emergency caesarean surgery under subarachnoid block. Methods: All the parturients who underwent emergency caesarean section under subarachnoid block during 6 months period were distributed a questionnaire in post-operative period. They were encouraged to fill and return the form within 15 days. Patient satisfaction and the self-expressed problems were analysed at the end of 6 months. Results: One hundred and seventy five out of 220 parturients responded. 58.3% of them said that they were explained about the anaesthesia prior to surgery and 85.3% overall remained anxious. With people around them, 93.1% of them felt comfortable and 91.4% expressed that they were made comfortable inside the theatre. The self-expressed problems were shivering (43.4%, breathlessness (21.7%, pain (20%, post-operative headache (15.4% and backache (19.4%. Parturients who heard their babies cry was 85.1%. After their babies were shown after delivery, 77.1% mothers slept well; 86.9% fed their babies within 4 h of delivery. Conclusion: Pre-operative communication in emergency caesarean section by health personnel did not reduce the anxiety level, which shows that communication was ineffective. Intra-operative psychological support like making the patient comfortable, showing baby to mother and early breast feeding improve bonding between child and mother and essentially contribute to patient satisfaction.

  5. Vortex operators in gauge field theories

    International Nuclear Information System (INIS)

    Polchinski, J.

    1980-07-01

    Several related aspects of the 't Hooft vortex operator are studied. The current picture of the vacuum of quantum chromodynamics, the idea of dual field theories, and the idea of the vortex operator are reviewed first. The Abelian vortex operator written in terms of elementary fields and the calculation of its Green's functions are considered. A two-dimensional solvable model of a Dirac string is presented. The expression of the Green's functions more neatly in terms of Wu and Yang's geometrical idea of sections is addressed. The renormalization of the Green's functions of two kinds of Abelian looplike operators, the Wilson loop and the vortex operator, is studied; for both operators only an overall multiplicative renormalization is needed. In the case of the vortex this involves a surprising cancellation. Next, the dependence of the Green's functions of the Wilson and 't Hooft operators on the nature of the vacuum is discussed. The cluster properties of the Green's functions are emphasized. It is seen that the vortex operator in a massive Abelian theory always has surface-like clustering. The form of Green's functions in terms of Feynman graphs is the same in Higgs and symmetric phases; the difference appears in the sum over all tadpole trees. Finally, systems having fields in the fundamental representation are considered. When these fields enter only weakly into the dynamics, a vortex-like operator is anticipated. Any such operator can no longer be local looplike, but must have commutators at long range. A U(1) lattice gauge theory with two matter fields, one singly charged (fundamental) and one doubly charged (adjoint), is examined. When the fundamental field is weakly coupled, the expected phase transitions are found. When it is strongly coupled, the operator still appears to be a good order parameter, a discontinuous change in its behavior leads to a new phase transition. 18 figures

  6. Nuclear axial current operators to fourth order in chiral effective field theory

    Energy Technology Data Exchange (ETDEWEB)

    Krebs, H., E-mail: hermann.krebs@rub.de [Institut für Theoretische Physik II, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Epelbaum, E., E-mail: evgeny.epelbaum@rub.de [Institut für Theoretische Physik II, Ruhr-Universität Bochum, D-44780 Bochum (Germany); Kavli Institute for Theoretical Physics, University of California, Santa Barbara, CA 93016 (United States); Meißner, U.-G., E-mail: meissner@hiskp.uni-bonn.de [Helmholtz-Institut für Strahlen- und Kernphysik and Bethe Center for Theoretical Physics, Universität Bonn, D-53115 Bonn (Germany); Institut für Kernphysik, Institute for Advanced Simulation, and Jülich Center for Hadron Physics, Forschungszentrum Jülich, D-52425 Jülich (Germany); JARA - High Performance Computing, Forschungszentrum Jülich, D-52425 Jülich (Germany)

    2017-03-15

    We present the complete derivation of the nuclear axial charge and current operators as well as the pseudoscalar operators to fourth order in the chiral expansion relative to the dominant one-body contribution using the method of unitary transformation. We demonstrate that the unitary ambiguity in the resulting operators can be eliminated by the requirement of renormalizability and by matching of the pion-pole contributions to the nuclear forces. We give expressions for the renormalized single-, two- and three-nucleon contributions to the charge and current operators and pseudoscalar operators including the relevant relativistic corrections. We also verify explicitly the validity of the continuity equation.

  7. WIPP - Pre-Licensing and Operations: Developer and Regulator Perspectives

    International Nuclear Information System (INIS)

    Peake, Tom; Patterson, R.

    2014-01-01

    The Waste Isolation Pilot Plant (WIPP) is a disposal system for defense-related transuranic (TRU) radioactive waste. Developed by the Department of Energy (DOE), WIPP is located in Southeastern New Mexico: radioactive waste is disposed of 2,150 feet underground in an ancient layer of salt with a total capacity of 6.2 million cubic feet of waste. Congress authorized the development and construction of WIPP in 1980 for the express purpose of providing a research and development facility to demonstrate the safe disposal of radioactive wastes resulting from the defense activities and programs of the United States. This paper makes a historical review of the site development, site operations (waste disposal operations started in 1999), communications between US EPA and DOE, the chronology of pre-licensing and pre-operations, the operational phase and the regulatory challenges, and the lessons learned after 12 years of operations

  8. Como obter vantagem competitiva utilizando business intelligence?

    Directory of Open Access Journals (Sweden)

    Avanilde Kemczinski

    2003-03-01

    Full Text Available Este artigo tem por objetivo definir Business Intelligence e identificar as tecnologias de informação e comunicação que dão suporte a este tipo de sistema de informação. Faz-se uma contextualização sobre o conceito e as tipologias de sistemas de informação (SI. Data Warehouse, Data Mart e Data Mining são os recursos tecnológicos denominados de Back-end system, utilizados para armazenar dados relevantes e extrair padrões de comportamento e tendências dos processos organizacionais. Os DSS (Decision Support Systems, EIS (Executive Information Systems e ferramentas de OLAP (On-Line Analytical Processing são caracterizados como Front-end systems para os sistemas de Business Intelligence, requerendo-se ampla funcionalidade, flexibilidade e usabilidade para que o usuário possa fazer a transformação das informações em conhecimento estratégico que apóie a tomada de decisão organizacional, objetivando a vantagem competitiva. Palavras-chave: Sistemas de Informação, Business Intelligence, Data Mining, Data Warehouse, OLAP.

  9. Following the time course of face gender and expression processing: a task-dependent ERP study.

    Science.gov (United States)

    Valdés-Conroy, Berenice; Aguado, Luis; Fernández-Cahill, María; Romero-Ferreiro, Verónica; Diéguez-Risco, Teresa

    2014-05-01

    The effects of task demands and the interaction between gender and expression in face perception were studied using event-related potentials (ERPs). Participants performed three different tasks with male and female faces that were emotionally inexpressive or that showed happy or angry expressions. In two of the tasks (gender and expression categorization) facial properties were task-relevant while in a third task (symbol discrimination) facial information was irrelevant. Effects of expression were observed on the visual P100 component under all task conditions, suggesting the operation of an automatic process that is not influenced by task demands. The earliest interaction between expression and gender was observed later in the face-sensitive N170 component. This component showed differential modulations by specific combinations of gender and expression (e.g., angry male vs. angry female faces). Main effects of expression and task were observed in a later occipito-temporal component peaking around 230 ms post-stimulus onset (EPN or early posterior negativity). Less positive amplitudes in the presence of angry faces and during performance of the gender and expression tasks were observed. Finally, task demands also modulated a positive component peaking around 400 ms (LPC, or late positive complex) that showed enhanced amplitude for the gender task. The pattern of results obtained here adds new evidence about the sequence of operations involved in face processing and the interaction of facial properties (gender and expression) in response to different task demands. Copyright © 2014 Elsevier B.V. All rights reserved.

  10. Mayer Transfer Operator Approach to Selberg Zeta Function

    DEFF Research Database (Denmark)

    Momeni, Arash; Venkov, Alexei

    . In a special situation the dynamical zeta function is defined for a geodesic flow on a hyperbolic plane quotient by an arithmetic cofinite discrete group. More precisely, the flow is defined for the corresponding unit tangent bundle. It turns out that the Selberg zeta function for this group can be expressed...... in terms of a Fredholm determinant of a classical transfer operator of the flow. The transfer operator is defined in a certain space of holomorphic functions and its matrix representation in a natural basis is given in terms of the Riemann zeta function and the Euler gamma function....

  11. Vortex operators in gauge field theories

    International Nuclear Information System (INIS)

    Polchinski, J.G.

    1980-01-01

    We study several related aspects of the t Hooft vortex operator. The first chapter reviews the current picture of the vacuum of quantum chromodynamics, the idea of dual field theories, and the idea of the vortex operator. The second chapter deals with the Abelian vortex operator written in terms of elementary fields and with the calculation of its Green's functions. The Dirac veto problem appears in a new guise. We present a two dimensional solvable model of a Dirac string. This leads us to a new solution of the veto problem; we discuss its extension to four dimensions. We then show how the Green's functions can be expressed more neatly in terms of Wu and Yang's geometrical idea of sections. In the third chapter we discuss the dependence of the Green's functions of the Wilson and t Hooft operators on the nature of the vacuum. In the fourth chapter we consider systems which have fields in the fundamental representation, so that there are no vortex operators. When these fields enter only weakly into the dynamics, as is the case in QCD and in real superconductors, we would expect to be able to define a vortex-like operator. We show that any such operator can no longer be local looplike, but must have commutators at long range. We can still find an operator with useful properties, its cluster property, though more complicated than that of the usual vortex operator, still appears to distinguish Higgs, confining and perturbative phases. To test this, we consider a U(1) lattice gauge theory with two matter fields, one singly charged (fundamental) and one doubly charged (adjoint)

  12. Two-spinor description of massive particles and relativistic spin projection operators

    Directory of Open Access Journals (Sweden)

    A.P. Isaev

    2018-04-01

    Full Text Available On the basis of the Wigner unitary representations of the covering group ISL(2,C of the Poincaré group, we obtain spin-tensor wave functions of free massive particles with arbitrary spin. The wave functions automatically satisfy the Dirac–Pauli–Fierz equations. In the framework of the two-spinor formalism we construct spin-vectors of polarizations and obtain conditions that fix the corresponding relativistic spin projection operators (Behrends–Fronsdal projection operators. With the help of these conditions we find explicit expressions for relativistic spin projection operators for integer spins (Behrends–Fronsdal projection operators and then find relativistic spin projection operators for half integer spins. These projection operators determine the numerators in the propagators of fields of relativistic particles. We deduce generalizations of the Behrends–Fronsdal projection operators for arbitrary space–time dimensions D>2.

  13. Compositions and methods for xylem-specific expression in plant cells

    Energy Technology Data Exchange (ETDEWEB)

    Han, Kyung-Hwan; Ko, Jae-Heung

    2017-12-19

    The invention provides promoter sequences that regulate specific expression of operably linked sequences in developing xylem cells and/or in developing xylem tissue. The developing xylem-specific sequences are exemplified by the DX5, DX8, DX11, and DX15 promoters, portions thereof, and homologs thereof. The invention further provides expression vectors, cells, tissues and plants that contain the invention's sequences. The compositions of the invention and methods of using them are useful in, for example, improving the quantity (biomass) and/or the quality (wood density, lignin content, sugar content etc.) of expressed biomass feedstock products that may be used for bioenergy, biorefinary, and generating wood products such as pulp, paper, and solid wood.

  14. Complex operator method of the hydrogen atom

    International Nuclear Information System (INIS)

    Jiang, X.

    1989-01-01

    Frequently the hydrogen atom eigenvalue problem is analytically solved by solving a radial wave equation for a particle in a Coulomb field. In this article, complex coordinates are introduced, and an expression for the energy levels of the hydrogen atom is obtained by means of the algebraic solution of operators. The form of this solution is in accord with that of the analytical solution

  15. Comparing GPU and CPU in OLAP Cubes Creation

    Science.gov (United States)

    Kaczmarski, Krzysztof

    GPGPU (General Purpose Graphical Processing Unit) programming is receiving more attention recently because of enormous computations speed up offered by this technology. GPGPU is applied in many branches of science and industry not excluding databases, even if this is not the primary field of expected benefits.

  16. Generalized space and linear momentum operators in quantum mechanics

    International Nuclear Information System (INIS)

    Costa, Bruno G. da; Borges, Ernesto P.

    2014-01-01

    We propose a modification of a recently introduced generalized translation operator, by including a q-exponential factor, which implies in the definition of a Hermitian deformed linear momentum operator p ^ q , and its canonically conjugate deformed position operator x ^ q . A canonical transformation leads the Hamiltonian of a position-dependent mass particle to another Hamiltonian of a particle with constant mass in a conservative force field of a deformed phase space. The equation of motion for the classical phase space may be expressed in terms of the generalized dual q-derivative. A position-dependent mass confined in an infinite square potential well is shown as an instance. Uncertainty and correspondence principles are analyzed

  17. The algebraic geometry of Harper operators

    International Nuclear Information System (INIS)

    Li, Dan

    2011-01-01

    Following an approach developed by Gieseker, Knoerrer and Trubowitz for discretized Schroedinger operators, we study the spectral theory of Harper operators in dimensions 2 and 1, as a discretized model of magnetic Laplacians, from the point of view of algebraic geometry. We describe the geometry of an associated family of Bloch varieties and compute their density of states. Finally, we also compute some spectral functions based on the density of states. We discuss the difference between the cases with rational or irrational parameters: for the two-dimensional Harper operator, the compactification of the Bloch variety is an ordinary variety in the rational case and an ind-pro-variety in the irrational case. This gives rise, at the algebro-geometric level of Bloch varieties, to a phenomenon similar to the Hofstadter butterfly in the spectral theory. In dimension 2, the density of states can be expressed in terms of period integrals over Fermi curves, where the resulting elliptic integrals are independent of the parameters. In dimension 1, for the almost Mathieu operator, with a similar argument, we find the usual dependence of the spectral density on the parameter, which gives rise to the well-known Hofstadter butterfly picture. (paper)

  18. Operator interface to the ORIC control system

    International Nuclear Information System (INIS)

    Ludemann, C.A.; Casstevens, B.J.

    1983-01-01

    The Oak Ridge Isochronous Cyclotron (ORIC) was built in the early 1960s with a hard-wired manual control system. Presently, it serves as a variable-energy heavy-ion cyclotron with an internal ion source, or as an energy booster for the new 25 MV tandem electrostatic accelerator of the Holifield Heavy Ion Facility. One factor which has kept the cyclotron the productive research tool it is today is the gradual transfer of its control functions to a computer-based system beginning in the 1970s. This particular placement of a computer between an accelerator and its operators afforded some unique challenges and opportunities that would not be encountered today. Historically, the transformation began at a time when computers were just beginning to gain acceptance as reliable operational tools. Veteran operators with tens of years of accelerator experience justifiably expressed skepticism that this improvement would aid them, particularly if they had to re-learn how to operate the machine. The confidence of the operators was gained when they realized that one of the primary principles of ergonomics was being upheld. The computer software and hardware was being designed to serve them and not the computer

  19. On the expressiveness and decidability of higher-order process calculi

    NARCIS (Netherlands)

    Lanese, Ivan; Perez, Jorge A.; Sangiorgi, Davide; Schmitt, Alan

    In higher-order process calculi, the values exchanged in communications may contain processes. A core calculus of higher-order concurrency is studied; it has only the operators necessary to express higher-order communications: input prefix, process output, and parallel composition. By exhibiting a

  20. Automation-aided Task Loads Index based on the Automation Rate Reflecting the Effects on Human Operators in NPPs

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Seungmin; Seong, Poonghyun [Korea Advanced Institute of Science and Technology, Daejeon (Korea, Republic of); Kim, Jonghyun [KEPCO International Nuclear Graduate School, Ulsan (Korea, Republic of)

    2013-05-15

    Many researchers have found that a high automation rate does not guarantee high performance. Therefore, to reflect the effects of automation on human performance, a new estimation method of the automation rate that considers the effects of automation on human operators in nuclear power plants (NPPs) was suggested. These suggested measures express how much automation support human operators but it cannot express the change of human operators' workload, whether the human operators' workload is increased or decreased. Before considering automation rates, whether the adopted automation is good or bad might be estimated in advance. In this study, to estimate the appropriateness of automation according to the change of the human operators' task loads, automation-aided task loads index is suggested based on the concept of the suggested automation rate. To insure plant safety and efficiency on behalf of human operators, various automation systems have been installed in NPPs, and many works which were previously conducted by human operators can now be supported by computer-based operator aids. According to the characteristics of the automation types, the estimation method of the system automation and the cognitive automation rate were suggested. The proposed estimation method concentrates on the effects of introducing automation, so it directly express how much the automated system support human operators. Based on the suggested automation rates, the way to estimate how much the automated system can affect the human operators' cognitive task load is suggested in this study. When there is no automation, the calculated index is 1, and it means there is no change of human operators' task load.

  1. Serial analysis of gene expression (SAGE) in rat liver regeneration

    International Nuclear Information System (INIS)

    Cimica, Velasco; Batusic, Danko; Haralanova-Ilieva, Borislava; Chen, Yonglong; Hollemann, Thomas; Pieler, Tomas; Ramadori, Giuliano

    2007-01-01

    We have applied serial analysis of gene expression for studying the molecular mechanism of the rat liver regeneration in the model of 70% partial hepatectomy. We generated three SAGE libraries from a normal control liver (NL library: 52,343 tags), from a sham control operated liver (Sham library: 51,028 tags), and from a regenerating liver (PH library: 53,061 tags). By SAGE bioinformatics analysis we identified 40 induced genes and 20 repressed genes during the liver regeneration. We verified temporal expression of such genes by real time PCR during the regeneration process and we characterized 13 induced genes and 3 repressed genes. We found connective tissue growth factor transcript and protein induced very early at 4 h after PH operation before hepatocytes proliferation is triggered. Our study suggests CTGF as a growth factor signaling mediator that could be involved directly in the mechanism of liver regeneration induction

  2. Induction by Coinduction and Control Operators in Call-by-Name

    Directory of Open Access Journals (Sweden)

    Yoshihiko Kakutani

    2013-09-01

    Full Text Available This paper studies emulation of induction by coinduction in a call-by-name language with control operators. Since it is known that call-by-name programming languages with control operators cannot have general initial algebras, interaction of induction and control operators is often restricted to effect-free functions. We show that some class of such restricted inductive types can be derived from full coinductive types by the power of control operators. As a typical example of our results, the type of natural numbers is represented by the type of streams. The underlying idea is a counterpart of the fact that some coinductive types can be expressed by inductive types in call-by-name pure language without side-effects.

  3. Transition operators in electromagnetic-wave diffraction theory - General theory

    Science.gov (United States)

    Hahne, G. E.

    1992-01-01

    A formal theory is developed for the scattering of time-harmonic electromagnetic waves from impenetrable immobile obstacles with given linear, homogeneous, and generally nonlocal boundary conditions of Leontovich (impedance) type for the wave of the obstacle's surface. The theory is modeled on the complete Green's function and the transition (T) operator in time-independent formal scattering theory of nonrelativistic quantum mechanics. An expression for the differential scattering cross section for plane electromagnetic waves is derived in terms of certain matrix elements of the T operator for the obstacle.

  4. Euler polynomials and identities for non-commutative operators

    Science.gov (United States)

    De Angelis, Valerio; Vignat, Christophe

    2015-12-01

    Three kinds of identities involving non-commutating operators and Euler and Bernoulli polynomials are studied. The first identity, as given by Bender and Bettencourt [Phys. Rev. D 54(12), 7710-7723 (1996)], expresses the nested commutator of the Hamiltonian and momentum operators as the commutator of the momentum and the shifted Euler polynomial of the Hamiltonian. The second one, by Pain [J. Phys. A: Math. Theor. 46, 035304 (2013)], links the commutators and anti-commutators of the monomials of the position and momentum operators. The third appears in a work by Figuieira de Morisson and Fring [J. Phys. A: Math. Gen. 39, 9269 (2006)] in the context of non-Hermitian Hamiltonian systems. In each case, we provide several proofs and extensions of these identities that highlight the role of Euler and Bernoulli polynomials.

  5. Curcumin attenuates the expression of NMDAR-NR1 in Chronic Constructive Injury model of neuropathic pain

    Directory of Open Access Journals (Sweden)

    Xiangdi Yu

    2015-03-01

    Full Text Available Objective: Neuropathic pain is a prevalent desease that greatly impairs the patients’ quality of life. A lack of the understanding of its aetiology, inadequate relief, and development of tolerance and potential toxicity of classical antinociceptives warrant the investigation of the newer agents to relieve this pain. The aim of the present study was to explore the antinociceptic effect of curcumin and its effect on expression of N-methyl-D-aspartate (NMDA receptor in spinal dorsal horn and dorsal root ganglion in chronic constriction injury (CCI mode of neuropathic pain of rats. Methods: Paw withdrawal mechanical threshold (PWMT and paw withdrawal thermal latency (PWTL of rats were measured on 2th pre-operative and 1, 3, 5, 7, 10, 14 post-operative days, and the expression of NMDAR NR-1 in spinal dorsal horn and DRG was measured by Immunohistochemical staining and western-blot. Results: CCI rats exhibited significant hyperalgesia after operation as compared with control rats. Chronic treatment with curcumin 100mg/kg/day for 14days starting from the 1 th day after CCI operation significantly attenuated PWMT and PWTL. Curcumin also inhibited the expression of NMDAR NR-1 in spinal dorsal horn and DRG. Conclusion: These results indicate an antinociceptive activity of curcumin possibly through its inhibitory action on expression of NMDAR NR-1 in spinal dorsal horn and DRG and point towards its potential to attenuate neuropathic pain.

  6. 17 CFR 229.1208 - (Item 1208) Oil and gas properties, wells, operations, and acreage.

    Science.gov (United States)

    2010-04-01

    ... properties, wells, operations, and acreage. 229.1208 Section 229.1208 Commodity and Securities Exchanges..., operations, and acreage. (a) Disclose, as of a reasonably current date or as of the end of the fiscal year... interests owned in gross wells or acres expressed as whole numbers and fractions of whole numbers. (3...

  7. Structural properties of the self-conjugate SU(3) tensor operators

    International Nuclear Information System (INIS)

    Lohe, M.A.; Biedenharn, L.C.; Louck, J.D.

    1977-01-01

    Denominator functions for the set of self-conjugate SU(3) tensor operators are explicitly obtained and shown to be uniquely related to SU(3) -invariant structural properties. This relationship becomes manifest through the appearance of zeroes of the denominator functions which thereby express the fundamental null space properties of SU(3) tensor operators. It is demonstrated that there exist characteristic denominator functions whose zeroes, in position and multiplicity, possess the interesting, and unexpected, property of forming SU(3) weight space patterns

  8. An Analysis of the Effect of Operations Management Practices on Performance

    OpenAIRE

    Battistoni, Elisa; Bonacelli, Andra; Fronzetti Colladon, Andrea; Schiraldi, Massimiliano M.

    2013-01-01

    In this paper we investigate the possible relationships among some optimization techniques used in Operations Management and the performance of SMEs that operate in the manufacturing sector. A model based on the Structural Equation Modelling (SEM) approach is used to analyse a dataset of small and medium-sized Italian enterprises. The model is expressed by a system of simultaneous equations and is solved through regression analysis. Taking advantage of the contributions presented previously, ...

  9. The Optimization of Passengers’ Travel Time under Express-Slow Mode Based on Suburban Line

    Directory of Open Access Journals (Sweden)

    Xiaobing Ding

    2016-01-01

    Full Text Available The suburban line connects the suburbs and the city centre; it is of huge advantage to attempt the express-slow mode. The passengers’ average travel time is the key factor to reflect the level of rail transport services, especially under the express-slow mode. So it is important to study the passengers’ average travel time under express-slow, which can get benefit on the optimization of operation scheme. First analyze the main factor that affects passengers’ travel time and then mine the dynamic interactive relationship among the factors. Second, a new passengers’ travel time evolution algorithm is proposed after studying the stop schedule and the proportion of express/slow train, and then membrane computing theory algorithm is introduced to solve the model. Finally, Shanghai Metro Line 22 is set as an example to apply the optimization model to calculate the total passengers’ travel time; the result shows that the total average travel time under the express-slow mode can save 1 minute and 38 seconds; the social influence and value of it are very huge. The proposed calculation model is of great help for the decision of stop schedule and provides theoretical and methodological support to determine the proportion of express/slow trains, improves the service level, and enriches and complements the rail transit operation scheme optimization theory system.

  10. Three Years of Experience of Wet Gas Allocation on Canyon Express

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Aditya; Hall, James; Letton, Winsor

    2005-07-01

    In September 2002, production was begun from the three fields that together form the Canyon Express System- King's Peak, Aconcagua, and Camden Hills. The 9 wells from these fields are connected to a pair of 12-inch flow lines carrying the commingled wet gas a distance of approximately 92 kilometers back to the Canyon Station platform for processing. At the 21st NSFMW in October 2003, an initial report was given on the status of Wet Gas Allocation for the Canyon Express project. As discussed in that paper, dual-differential, subsea wet gas meters were chosen for the task of allocating gas and liquids back to individual wells. However, since the gas from all three fields was very dry (Lockhart-Martinelli parameter less than 0.01) and because the operating pressures were quite high (250 bar), application of the dual-differential function of the meters yielded errors in both liquid and gas flow rates. Furthermore, as these problems were being uncovered, scale was beginning to collect inside some of the meters. Taken together, these problems produced system imbalances as great as 20%. To address the problems, one of the individual flow metering elements within each wet gas meter was chosen as the allocation meter, operating as a single-phase gas meter. After three years of operation of the Canyon Express Project, considerable experience has been accumulated. Since at the time it held the record for deep water hydrocarbon production, application of the technologies discussed here were challenging and required considerable flexibility. It is believed that the Canyon Express experiences will benefit future deep water flow metering projects. The knowledge acquired thus far is surveyed and summarized. The emphasis is on the technical aspects. (tk)

  11. An Analysis of the Effect of Operations Management Practices on Performance

    Directory of Open Access Journals (Sweden)

    Elisa Battistoni Andrea Bonacelli

    2013-09-01

    Full Text Available In this paper we investigate the possible relationships among some optimization techniques used in Operations Management and the performance of SMEs that operate in the manufacturing sector. A model based on the Structural Equation Modelling (SEM approach is used to analyse a dataset of small and medium-sized Italian enterprises. The model is expressed by a system of simultaneous equations and is solved through regression analysis. Taking advantage of the contributions presented previously, we focus our research on the Italian economy, highlighting the importance of Operations Management practices, which are relevant drivers of these firms’ performances.

  12. The operators governing quantum fluctuations of Yang-Mills multi-instantons on S4 and their Seeley coefficients

    International Nuclear Information System (INIS)

    Daniel, M.

    1980-01-01

    We give explicit expressions for the Seeley coefficients of the fluctuation operator and the operator that appears in the Faddeev-Popov determinant, which arise in the calculation of quantum fluctuations around Yang-Mills multi-instantons. (orig.)

  13. Neuropeptide Y receptor-expressing dorsal horn neurons: role in nocifensive reflex and operant responses to aversive cold after CFA inflammation.

    Science.gov (United States)

    Lemons, L L; Wiley, R G

    2012-08-02

    The spinal Neuropeptide Y (NPY) system is a potential target for development of new pain therapeutics. NPY and two of its receptors (Y1 and Y2) are found in the superficial dorsal horn of the spinal cord, a key area of nociceptive gating and modulation. Lumbar intrathecal injection of (NPY) is antinociceptive, reducing hyper-reflexia to thermal and mechanical stimulation, particularly after nerve injury and inflammation. We have also shown that intrathecal injection of the targeted cytotoxin, Neuropeptide Y-sap (NPY-sap), is also antinociceptive, reducing nocifensive reflex responses to noxious heat and formalin. In the present study, we sought to determine the role of dorsal horn Y1R-expressing neurons in pain by destroying them with NPY-sap and testing the rats on three operant tasks. Lumbar intrathecal NPY-sap (1) reduced Complete Freund's Adjuvant (CFA)-induced hyper-reflexia on the 10°C cold plate, (2) reduced cold aversion on the thermal preference and escape tasks, (3) was analgesic to noxious heat on the escape task, (4) reduced the CFA-induced allodynia to cold temperatures experienced on the thermal preference, feeding interference, and escape tasks, and (5) did not inhibit or interfere with morphine analgesia. Published by Elsevier Ltd.

  14. A Gene Expression Classifier of Node-Positive Colorectal Cancer

    Directory of Open Access Journals (Sweden)

    Paul F. Meeh

    2009-10-01

    Full Text Available We used digital long serial analysis of gene expression to discover gene expression differences between node-negative and node-positive colorectal tumors and developed a multigene classifier able to discriminate between these two tumor types. We prepared and sequenced long serial analysis of gene expression libraries from one node-negative and one node-positive colorectal tumor, sequenced to a depth of 26,060 unique tags, and identified 262 tags significantly differentially expressed between these two tumors (P < 2 x 10-6. We confirmed the tag-to-gene assignments and differential expression of 31 genes by quantitative real-time polymerase chain reaction, 12 of which were elevated in the node-positive tumor. We analyzed the expression levels of these 12 upregulated genes in a validation panel of 23 additional tumors and developed an optimized seven-gene logistic regression classifier. The classifier discriminated between node-negative and node-positive tumors with 86% sensitivity and 80% specificity. Receiver operating characteristic analysis of the classifier revealed an area under the curve of 0.86. Experimental manipulation of the function of one classification gene, Fibronectin, caused profound effects on invasion and migration of colorectal cancer cells in vitro. These results suggest that the development of node-positive colorectal cancer occurs in part through elevated epithelial FN1 expression and suggest novel strategies for the diagnosis and treatment of advanced disease.

  15. Prognostic significance of XRCC4 expression in hepatocellular carcinoma

    Science.gov (United States)

    Huang, Xiao-Ying; Yao, Jin-Guang; Wang, Chao; Wei, Zhong-Hong; Ma, Yun; Wu, Xue-Min; Luo, Chun-Ying; Xia, Qiang; Long, Xi-Dai

    2017-01-01

    Background Our previous investigations have shown that the variants of X-ray repair complementing 4 (XRCC4) may be involved in hepatocellular carcinoma (hepatocarcinoma) tumorigenesis. This study aimed to investigate the possible prognostic significance of XRCC4 expression for hepatocarcinoma patients and possible value for the selection of transarterial chemoembolization (TACE) treatment. Materials and Methods We conducted a hospital-based retrospective analysis (including 421 hepatocarcinoma cases) to analyze the effects of XRCC4 on hepatocarcinoma prognosis and TACE. The levels of XRCC4 expression were tested using immunohistochemistry. The sensitivity of cancer cells to anti-cancer drug doxorubicin was evaluated using the half-maximal inhibitory concentration (IC50). Results XRCC4 expression was significantly correlated with pathological features including tumor stage, liver cirrhosis, and micro-vessel density. XRCC4 expression was an independent prognostic factor of hepatocarcinoma, and TACE treatments had no effects on prognosis of hepatocarcinoma patients with high XRCC4 expression. More intriguingly, TACE improved the prognosis of hepatocarcinoma patients with low XRCC4 expression. Functionally, XRCC4 overexpression increased while XRCC4 knockdown reduced the IC50 of cancer cells to doxorubicin. Conclusions These results suggest that XRCC4 may be an independent prognostic factor for hepatocarcinoma patients, and that decreasing XRCC4 expression may be beneficial for post-operative adjuvant TACE treatment in hepatocarcinoma. PMID:29152133

  16. [Expression of IMP3 in osteosarcoma and its clinical significance].

    Science.gov (United States)

    Li, Kang-hua; Huang, Yue-ping; Zhang, Jun; Li, Guo-jun; Li, Si-hong

    2009-05-01

    To analyze the expressional variability of IMP3 between osteosarcoma and osteochondroma and explore its clinical significance. Paraffin sections from 68 patients with osteosarcoma and 20 patients with osteochondroma were examined for the expression of IMP3 by SP immunohistochemistry. The negative, weak positive, moderate positive and strong positive expression rates of IMP3 in 68 patients with osteosarcoma were 4.41% (3/68), 22.06% (15/68), 22.74% (19/68), 45.59% (31/68), respectively, which were significantly higher than those in 20 cases of osteochondroma tissues (P<0.01). The positive expression of IMP3 in osteosarcoma was negative correlation with the 3-year survival rate of osteosarcoma patients after the operation (P<0.01). The results suggest that IMP3 plays important roles in the tumorigenesis, progress and prognosis of osteosarcoma, and the expression of IMP3 may be an important feature of osteosarcoma.

  17. Breast cancer Ki67 expression preoperative discrimination by DCE-MRI radiomics features

    Science.gov (United States)

    Ma, Wenjuan; Ji, Yu; Qin, Zhuanping; Guo, Xinpeng; Jian, Xiqi; Liu, Peifang

    2018-02-01

    To investigate whether quantitative radiomics features extracted from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) are associated with Ki67 expression of breast cancer. In this institutional review board approved retrospective study, we collected 377 cases Chinese women who were diagnosed with invasive breast cancer in 2015. This cohort included 53 low-Ki67 expression (Ki67 proliferation index less than 14%) and 324 cases with high-Ki67 expression (Ki67 proliferation index more than 14%). A binary-classification of low- vs. high- Ki67 expression was performed. A set of 52 quantitative radiomics features, including morphological, gray scale statistic, and texture features, were extracted from the segmented lesion area. Three most common machine learning classification methods, including Naive Bayes, k-Nearest Neighbor and support vector machine with Gaussian kernel, were employed for the classification and the least absolute shrink age and selection operator (LASSO) method was used to select most predictive features set for the classifiers. Classification performance was evaluated by the area under receiver operating characteristic curve (AUC), accuracy, sensitivity and specificity. The model that used Naive Bayes classification method achieved the best performance than the other two methods, yielding 0.773 AUC value, 0.757 accuracy, 0.777 sensitivity and 0.769 specificity. Our study showed that quantitative radiomics imaging features of breast tumor extracted from DCE-MRI are associated with breast cancer Ki67 expression. Future larger studies are needed in order to further evaluate the findings.

  18. EXPRESS Rack Technology for Space Station

    Science.gov (United States)

    Davis, Ted B.; Adams, J. Brian; Fisher, Edward M., Jr.; Prickett, Guy B.; Smith, Timothy G.

    1999-01-01

    The EXPRESS rack provides accommodations for standard Mid-deck Locker and ISIS drawer payloads on the International Space Station. A design overview of the basic EXPRESS rack and two derivatives, the Human Research Facility and the Habitat Holding Rack, is given in Part I. In Part II, the design of the Solid State Power Control Module (SSPCM) is reviewed. The SSPCM is a programmable and remotely controllable power switching and voltage conversion unit which distributes and protects up to 3kW of 12OVDC and 28VDC power to payloads and rack subsystem components. Part III details the development and testing of a new data storage device, the BRP EXPRESS Memory Unit (BEMU). The BEMU is a conduction-cooled device which operates on 28VDC and is based on Boeing-modified 9GB commercial disk-drive technology. In Part IV results of a preliminary design effort for a rack Passive Damping System (PDS) are reported. The PDS is intended to isolate ISPR-based experiment racks from on-orbit vibration. System performance predictions based on component developmental testing indicate that such a system can provide effective isolation at frequencies of 1 Hz and above.

  19. Creation and annihilation operators for Nielsen-Olesen vortices in the coherent state approximation

    International Nuclear Information System (INIS)

    Pottinger, D.E.L.

    1978-01-01

    Using the standard techniques of canonical quantization, the author constructs approximate expressions for the creation and annihilation operators for Nielsen-Olesen vortices. The forms for the creation and annihilation operators are appropriate to situations where large-scale vortex condensation takes place. In particular, a phenomenon such as this is basic in the quark confinement schemes of Mandelstam and 't Hooft. (Auth.)

  20. Correlation functions of Coulomb branch operators

    Energy Technology Data Exchange (ETDEWEB)

    Gerchkovitz, Efrat [Weizmann Institute of Science,Rehovot 76100 (Israel); Gomis, Jaume [Perimeter Institute for Theoretical Physics,Waterloo, ON N2L 2Y5 (Canada); Ishtiaque, Nafiz [Perimeter Institute for Theoretical Physics,Waterloo, ON N2L 2Y5 (Canada); Department of Physics, University of Waterloo,Waterloo, ON N2L 3G1 (Canada); Karasik, Avner; Komargodski, Zohar [Weizmann Institute of Science,Rehovot 76100 (Israel); Pufu, Silviu S. [Joseph Henry Laboratories, Princeton University,Princeton, NJ 08544 (United States)

    2017-01-24

    We consider the correlation functions of Coulomb branch operators in four-dimensional N=2 Superconformal Field Theories (SCFTs) involving exactly one anti-chiral operator. These extremal correlators are the “minimal' non-holomorphic local observables in the theory. We show that they can be expressed in terms of certain determinants of derivatives of the four-sphere partition function of an appropriate deformation of the SCFT. This relation between the extremal correlators and the deformed four-sphere partition function is non-trivial due to the presence of conformal anomalies, which lead to operator mixing on the sphere. Evaluating the deformed four-sphere partition function using supersymmetric localization, we compute the extremal correlators explicitly in many interesting examples. Additionally, the representation of the extremal correlators mentioned above leads to a system of integrable differential equations. We compare our exact results with previous perturbative computations and with the four-dimensional tt{sup ∗} equations. We also use our results to study some of the asymptotic properties of the perturbative series expansions we obtain in N=2 SQCD.

  1. Arithmetical and geometrical means of generalized logarithmic and exponential functions: Generalized sum and product operators

    International Nuclear Information System (INIS)

    Arruda, Tiago Jose; Silva Gonzalez, Rodrigo; Sangaletti Tercariol, Cesar Augusto; Souto Martinez, Alexandre

    2008-01-01

    One-parameter generalizations of the logarithmic and exponential functions have been obtained as well as algebraic operators to retrieve extensivity. Analytical expressions for the successive applications of the sum or product operators on several values of a variable are obtained here. Applications of the above formalism are considered

  2. Projection operator method for collective tunneling transitions

    International Nuclear Information System (INIS)

    Kohmura, Toshitake; Ohta, Hirofumi; Hashimoto, Yukio; Maruyama, Masahiro

    2002-01-01

    Collective tunneling transitions take place in the case that a system has two nearly degenerate ground states with a slight energy splitting, which provides the time scale of the tunneling. The Liouville equation determines the evolution of the density matrix, while the Schroedinger equation determines that of a state. The Liouville equation seems to be more powerful for calculating accurately the energy splitting of two nearly degenerate eigenstates. However, no method to exactly solve the Liouville eigenvalue equation has been established. The usual projection operator method for the Liouville equation is not feasible. We analytically solve the Liouville evolution equation for nuclear collective tunneling from one Hartree minimum to another, proposing a simple and solvable model Hamiltonian for the transition. We derive an analytical expression for the splitting of energy eigenvalues from a spectral function of the Liouville evolution using a half-projected operator method. A full-order analytical expression for the energy splitting is obtained. We define the collective tunneling path of a microscopic Hamiltonian for collective tunneling, projecting the nuclear ground states onto n-particle n-hole state spaces. It is argued that the collective tunneling path sector of a microscopic Hamiltonian can be transformed into the present solvable model Hamiltonian. (author)

  3. Refined toric branes, surface operators and factorization of generalized Macdonald polynomials

    Science.gov (United States)

    Zenkevich, Yegor

    2017-09-01

    We find new universal factorization identities for generalized Macdonald polynomials on the topological locus. We prove the identities (which include all previously known forumlas of this kind) using factorization identities for matrix model averages, which are themselves consequences of Ding-Iohara-Miki constraints. Factorized expressions for generalized Macdonald polynomials are identified with refined topological string amplitudes containing a toric brane on an intermediate preferred leg, surface operators in gauge theory and certain degenerate CFT vertex operators.

  4. Konsolidasi Data Warehouse untuk Aplikasi Business Intelligence

    Directory of Open Access Journals (Sweden)

    Rudy Rudy

    2012-12-01

    Full Text Available As the business competition is getting strong, corporate leaders need complete data that as a basis for determining future business strategies. Similarly with management of company "A", a pharmaceutical company which has three distribution companies. Each distribution company already has a data warehouse to generate reports for each of them. For business operational and corporate strategies, chairman PT "A" requires an integrated report, so analysis of data owned by the three distribution companies can be done in a full reportto answer the problems faced by the managemet. Thus, data warehouse consilidation can be used as a solution for company "A". Methodology starts with analysis of information needs to be displayed on the application ofbusiness intelligence, data warehouse consolidation, ETL (extract, transform and load, data warehousing, OLAP and Dashboard. Using data warehouse consolidation, information access by management of company "A" can be done in a single presentation, which can display data comparison between the three distribution companies.

  5. Security model for VM in cloud

    Science.gov (United States)

    Kanaparti, Venkataramana; Naveen K., R.; Rajani, S.; Padmvathamma, M.; Anitha, C.

    2013-03-01

    Cloud computing is a new approach emerged to meet ever-increasing demand for computing resources and to reduce operational costs and Capital Expenditure for IT services. As this new way of computation allows data and applications to be stored away from own corporate server, it brings more issues in security such as virtualization security, distributed computing, application security, identity management, access control and authentication. Even though Virtualization forms the basis for cloud computing it poses many threats in securing cloud. As most of Security threats lies at Virtualization layer in cloud we proposed this new Security Model for Virtual Machine in Cloud (SMVC) in which every process is authenticated by Trusted-Agent (TA) in Hypervisor as well as in VM. Our proposed model is designed to with-stand attacks by unauthorized process that pose threat to applications related to Data Mining, OLAP systems, Image processing which requires huge resources in cloud deployed on one or more VM's.

  6. Does It Help to Use Mathematically Superfluous Brackets When Teaching the Rules for the Order of Operations?

    Science.gov (United States)

    Gunnarsson, Robert; Sönnerhed, Wang Wei; Hernell, Bernt

    2016-01-01

    The hypothesis that mathematically superfluous brackets can be useful when teaching the rules for the order of operations is challenged. The idea of the hypothesis is that with brackets it is possible to emphasize the order priority of one operation over another. An experiment was conducted where expressions with mixed operations were studied,…

  7. Object and operation supported maintenance for mining equipment

    Directory of Open Access Journals (Sweden)

    Walter Bartelmus

    2014-09-01

    Full Text Available The paper aroused in answer to discussion in Mining Magazine (MM September 2011 and July/August 2013. The paper shows that discussion given in the MM issue July/August 2013 does not fulfill expectations expressed in MM issue 2011. The presented paper is the review on maintenance that is based on condition monitoring as tool for detection of faults and failure prevention. Fault and failure are regarded as inevitable during the machine operation as the process of wear and the process of degradation. The question is, if one can influence the wear and degradation process, using condition monitoring. The paper will present technology (in reference to cited papers which demonstrates that the use of the proper method can influence the wear and machine degradation process, using proper condition monitoring techniques and knowing scenarios of wear and degradation process, the maintenance can be rationalized. The presented paper shows possible improvements which are needed to fulfill expectations expressed in MM September 2011 and they are not taken into consideration in MM July/August 3013. These improvements can be fulfilling on the bases of object and operation supported maintenance.

  8. Neo-adjuvant chemotherapy with cisplatin induces low expression of NMDA receptors and postoperative cognitive impairment.

    Science.gov (United States)

    Cheng, Jing; Liu, Xiaoqing; Cao, Longhui; Zhang, Tianhua; Li, Huiting; Lin, Wenqian

    2017-01-10

    Whether Neo-adjuvant chemotherapy can affect patients' postoperative brain function is not clear. In this study, we investigated the effect of preoperative cisplatin treatment on postoperative cognitive function and its possible mechanism in rats. Moreover, we also tested whether the NMDAR inhibitor memantine could attenuate cisplatin-induced alterations. 12-month-oldSprague-Dawley rats randomly received an intraperitoneal injection of either cisplatin once a week at a dose of 3mg/kg for three consecutive weeks or an equivalent volume of normal saline. After the injections, the normal saline injection group was divided into 3 groups (n=5 each): a normal saline group (group S), normal saline+pentobarbital group (group SP), and normal saline+pentobarbital+operation group (group SPO).The cisplatin injection group was divided into 3 groups: a cisplatin group (group C), cisplatin+pentobarbital group (group CP), and cisplatin+pentobarbital+operation group (group CPO).Rats in the group SP, SPO,CP and CPO were anaesthetized with sodium pentobarbital and then the SPO and CPO groups underwent a simple laparotomy operation. The effects of memantine were tested through two additional groups of rats (cisplatin+memantine group (group CM) and cisplatin+pentobarbital+operation+memantine group (group CPOM)). A Morris water maze test was performed to evaluate the spatial learning and memory ability five days after anesthesia or operation. After the test, the hippocampi were removed for detection of the expression of NMDAR by western bloting. The relevant protein expression levels of PSD95 and ERK1/2 were detected by western blot analysis. Rats treated with cisplatin had a longer mean escape latency and spent a shorter amount of time in the target quadrant than did the normal saline injection rats. Furthermore, the protein expression levels of NMDA receptors, PSD95 and ERK1/2 were decreased in cisplatin group and memantine could up-regulate their expression. These results suggest

  9. The algebraic geometry of Harper operators

    Science.gov (United States)

    Li, Dan

    2011-10-01

    Following an approach developed by Gieseker, Knörrer and Trubowitz for discretized Schrödinger operators, we study the spectral theory of Harper operators in dimensions 2 and 1, as a discretized model of magnetic Laplacians, from the point of view of algebraic geometry. We describe the geometry of an associated family of Bloch varieties and compute their density of states. Finally, we also compute some spectral functions based on the density of states. We discuss the difference between the cases with rational or irrational parameters: for the two-dimensional Harper operator, the compactification of the Bloch variety is an ordinary variety in the rational case and an ind-pro-variety in the irrational case. This gives rise, at the algebro-geometric level of Bloch varieties, to a phenomenon similar to the Hofstadter butterfly in the spectral theory. In dimension 2, the density of states can be expressed in terms of period integrals over Fermi curves, where the resulting elliptic integrals are independent of the parameters. In dimension 1, for the almost Mathieu operator, with a similar argument, we find the usual dependence of the spectral density on the parameter, which gives rise to the well-known Hofstadter butterfly picture.

  10. Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome

    OpenAIRE

    Xu Boqun; Dai Xiaonan; Cui YuGui; Gao Lingling; Dai Xue; Chao Gao; Diao Feiyang; Liu Jiayin; Li Gao; Mei Li; Yuan Zhang; Xiang Ma

    2013-01-01

    Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries. Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and ...

  11. Sixteen Years of International Co-operation. The OECD/NEA Co-operative Programme on Decommissioning

    International Nuclear Information System (INIS)

    Menon, S.; Valencia, L.

    2002-01-01

    The Co-operative Programme on Decommissioning under the administration of the Radioactive Waste Management Committee of the OECD Nuclear Energy Agency (NEA) has recently completed sixteen years of operation. The Programme, which is essentially an information exchange programme between decommissioning projects, came into being in 1985. It has grown from an initial 10 decommissioning projects from 7 countries to 39 projects from 14 countries today. From purely information exchange to start with, the Programme has, in later years, been functioning as a voice for the collective expression of views of the implementers of nuclear decommissioning. During the first sixteen years of the operation of the Co-operative Programme, nuclear decommissioning has grown from local specialist activities within projects to a competitive commercial industry. By the dismantling and release from regulatory control of over a dozen diverse nuclear facilities, the Programme has been able to demonstrate in practice, that nuclear decommissioning can be performed safely both for the workers and the public, and that this can be done at reasonable costs in an environmentally friendly fashion. During the recent years, discussions and work within the Co-operative Programme, specially within some of the Task Groups, have had/are having effects and repercussions not just in the field of nuclear decommissioning, but can possibly affect activities and regulations in other industries. This paper describes how the Programme and its activities and procedures have evolved over the years and indicate the directions of developments in the organization and execution of decommissioning projects. Finally, it gives a brief overview of the achievements of the Cooperative Programme and visualizes future developments in the field of nuclear decommissioning

  12. Updated requirements for control room annunciation: an operations perspective

    International Nuclear Information System (INIS)

    Davey, E.; Lane, L.

    2001-01-01

    The purpose of this paper is to describe the results of updating and aligning requirements for annunciation functionality and performance with current expectations for operational excellence. This redefinition of annunciation requirements was undertaken as one component of a project to characterize improvement priorities, establish the operational and economic basis for improvement, and identify preferred implementation options for Ontario Power Generation plants. The updated requirements express the kinds of information support annunciation should provide to Operations staff to support the detection, recognition and response to changes in plant conditions. The updated requirements were developed using several types of information: management and industry expectations for operations excellence, previous definitions of user needs for annunciation, and operational and ergonomic principles. Operations and engineering staff at several stations have helped refine and complete the initial requirements definition. Application of these updated requirements is expected to lead to more effective and task relevant annunciation system improvements that better serve plant operation needs. The paper outlines the project rationale, reviews development objectives, discusses the approaches applied for requirements definition and organization, describes key requirements findings in relation to current operations experience, and discusses the proposed application of these requirements for guiding future annunciation system improvements. (author)

  13. Correlation of contrast-enhanced ultrasound parameters with oncogene expression and cell proliferation activity in breast cancer

    Institute of Scientific and Technical Information of China (English)

    Ce Zhang

    2017-01-01

    Objective: To study the correlation of contrast-enhanced ultrasound parameters with oncogene expression and cell proliferation activity in breast cancer. Methods: Breast cancer lesions and benign breast lesions surgically removed in Zigong Third People's Hospital between May 2014 and February 2017 were selected, contrast-enhanced ultrasound was done before operation to draw the time-intensity curve and calculate the area under the curve (AUC), and the expression of proliferation molecules and tumor suppressor genes were detected after operation. Results:The contrast-enhanced ultrasound parameter AUC of the breast cancer lesion was greatly higher than that of the benign breast lesion; ECT2, ZKSCAN3, USP39 and EphA2 mRNA expression in breast cancer lesions were obviously higher than those in benign breast lesions whereas HPK1, TCEAL17, CCN5, ATG2B and ATG4D mRNA expression were greatly lower than those in benign breast lesions; ECT2, ZKSCAN3, USP39 and EphA2 mRNA expression in breast cancer lesions with high AUC were greatly higher than those in breast cancer lesions with low AUC whereas HPK1, TCEAL17, CCN5, ATG2B and ATG4D mRNA expression were greatly lower than those in breast cancer lesions with low AUC. Conclusion: The contrast-enhanced ultrasound parameter AUC of breast cancer lesion significantly increases and is closely related to the higher expression of pro-proliferation molecules and the lower expression of tumor suppressor genes.

  14. Data Warehousing at the Marine Corps Institute

    Science.gov (United States)

    2003-09-01

    applications exists for several reasons. It allows for data to be extracted from many sources, by “cleaned”, and stored into one large data facility ...exists. Key individuals at MCI, or the so called “knowledge workers” will be educated , and try to brainstorm possible data relationships that can...They include querying and reporting, On-Line Analytical Processing (OLAP) and statistical analysis, and data mining. 1. Queries and Reports The

  15. SQL Server Analysis Services 2012 cube development cookbook

    CERN Document Server

    Dewald, Baya; Hughes, Steve

    2013-01-01

    A practical cookbook packed with recipes to help developers produce data cubes as quickly as possible by following step by step instructions, rather than explaining data mining concepts with SSAS.If you are a BI or ETL developer using SQL Server Analysis services to build OLAP cubes, this book is ideal for you. Prior knowledge of relational databases and experience with Excel as well as SQL development is required.

  16. Large clusters of co-expressed genes in the Drosophila genome.

    Science.gov (United States)

    Boutanaev, Alexander M; Kalmykova, Alla I; Shevelyov, Yuri Y; Nurminsky, Dmitry I

    2002-12-12

    Clustering of co-expressed, non-homologous genes on chromosomes implies their co-regulation. In lower eukaryotes, co-expressed genes are often found in pairs. Clustering of genes that share aspects of transcriptional regulation has also been reported in higher eukaryotes. To advance our understanding of the mode of coordinated gene regulation in multicellular organisms, we performed a genome-wide analysis of the chromosomal distribution of co-expressed genes in Drosophila. We identified a total of 1,661 testes-specific genes, one-third of which are clustered on chromosomes. The number of clusters of three or more genes is much higher than expected by chance. We observed a similar trend for genes upregulated in the embryo and in the adult head, although the expression pattern of individual genes cannot be predicted on the basis of chromosomal position alone. Our data suggest that the prevalent mechanism of transcriptional co-regulation in higher eukaryotes operates with extensive chromatin domains that comprise multiple genes.

  17. An Estimation of Operator's Diagnostic Time for Feed-And-Bleed Operation under Various Scenarios

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Bo Gyung; Kang, Hyun Gook [KAIST, Daejeon (Korea, Republic of); Yoon, Ho Joon [Khalifa University of Science, Abu Dhabi (United Arab Emirates)

    2015-10-15

    In order to assess realistic safety of plant, effects of interactions between components, operator, and plant condition are needed to be considered in the PSA model. One of the important issues to estimate the CDF is the estimation of human error probability (HEP). When an accident occurs, operators follow the emergency operating procedure and check various alarm, parameters, and signals. In the conventional Korean PSA model, the Korean standard HRA (K-HRA) method is used. In this method, the HEP is the sum of diagnosis error probability and execution error probability. A diagnosis error probability is expressed by the available time for diagnosis and adjusting performance shaping factors, and an execution error probability is a function of task type and stress level. Available time for diagnosis is very important factor of HEP. If the available time for diagnosis is short, the HEP becomes high. In order to obtain the realistic risk assessment results, we first focus on the estimation of HEP considering the plant dynamics under various scenarios. Target operation and scenarios are feed-and bleed operation (F and B operation) and total loss of feedwater (TLOFW) accident with/without loss of coolant accident (LOCA). One of the highest HEP is HEP of FnB operation. In additional, Scenarios, which are related to combination secondary heat removal failure and primary heat removal failure, are most critical core damage scenario of the combined accident except scenarios related to station black out (SBO). In these scenarios, the FnB operation is last resort to prevent core damage. To estimate available operator diagnosis time, we identify the relationship between accidents, mitigation function, and plant condition. Distribution of available time of diagnosis was estimated using the MOSAIQUE. The variables are break size, break timing, trip timing of RCP, and availability of high pressure safety injection (HPSI) pump under the TLOFW accident with LOCA. For Type 1 accident

  18. Equivalence of the super Lax and local Dunkl operators for Calogero-like models

    International Nuclear Information System (INIS)

    Neelov, A I

    2004-01-01

    Following Shastry and Sutherland I construct the super Lax operators for the Calogero model in the oscillator potential. These operators can be used for the derivation of the eigenfunctions and integrals of motion of the Calogero model and its supersymmetric version. They allow us to infer several relations involving the Lax matrices for this model in a fast way. It is shown that the super Lax operators for the Calogero and Sutherland models can be expressed in terms of the supercharges and so-called local Dunkl operators constructed in our recent paper with M Ioffe. Several important relations involving Lax matrices and Hamiltonians of the Calogero and Sutherland models are easily derived from the properties of Dunkl operators

  19. Improvement of rate of operation of LWRs, (2)

    International Nuclear Information System (INIS)

    Makiura, Ryutaro

    1978-01-01

    In the first part, the growing importance of improving the rate of operation of nuclear power plants is expressed in view of the big unit capacity of the present plants. The following parts of this report are devoted to the description of various measures for improving the reliability and the rate of operation of BWR plants from the standpoint of plant makers. The first subject is the early solution of ''singular troubles'', for example, the channel wear due to the oscillation of LPRM strings. The second subject is ''ordinary troubles'' such as valve leak and malfunction, deterioration of various parts, and vibration of pipes. The improvement of load factor is discussed in the third part in connection with the present efforts to abolish the PCIOMR operation and to employ the fine motion of control rod-driving mechanism. The final subject concerns with the efforts for shortening the time required for regular inspection. Review of inspection items and shortening of their required time, reduction of radiation exposure automated and remote-controlled operation, and intensive training of operators are the main subjects discussed here. (Aoki, K.)

  20. The Risk Assessment of the Firm Activity Using the Operating Lever

    Directory of Open Access Journals (Sweden)

    Anca-Jarmila GUTA

    2016-09-01

    Full Text Available This paper aims identify the ways in which the risk generally and specifically operating the risk can compete in the failure or success of a business. For awareness phenomena, actions and events that can generate losses for the adoption of prudent behavior it is necessary in a first step to identify the types of risk that a company may face. For the company that makes the subject of this paper have revealed a risk of exploitation by means of operating leverage, expressing elasticity operating result of the company in relation to its turn over. Analysing the evolution of the society we found that increasing the volume of activity on the period under study led to an increase in operating leverage which means that society has become more risky because it involves revenue growth and increased operating costs.

  1. Photosynthetic control of electron transport and the regulation of gene expression.

    Science.gov (United States)

    Foyer, Christine H; Neukermans, Jenny; Queval, Guillaume; Noctor, Graham; Harbinson, Jeremy

    2012-02-01

    The term 'photosynthetic control' describes the short- and long-term mechanisms that regulate reactions in the photosynthetic electron transport (PET) chain so that the rate of production of ATP and NADPH is coordinated with the rate of their utilization in metabolism. At low irradiances these mechanisms serve to optimize light use efficiency, while at high irradiances they operate to dissipate excess excitation energy as heat. Similarly, the production of ATP and NADPH in ratios tailored to meet demand is finely tuned by a sophisticated series of controls that prevents the accumulation of high NAD(P)H/NAD(P) ratios and ATP/ADP ratios that would lead to potentially harmful over-reduction and inactivation of PET chain components. In recent years, photosynthetic control has also been extrapolated to the regulation of gene expression because mechanisms that are identical or similar to those that serve to regulate electron flow through the PET chain also coordinate the regulated expression of genes encoding photosynthetic proteins. This requires coordinated gene expression in the chloroplasts, mitochondria, and nuclei, involving complex networks of forward and retrograde signalling pathways. Photosynthetic control operates to control photosynthetic gene expression in response to environmental and metabolic changes. Mining literature data on transcriptome profiles of C(3) and C(4) leaves from plants grown under high atmospheric carbon dioxide (CO(2)) levels compared with those grown with ambient CO(2) reveals that the transition to higher photorespiratory conditions in C(3) plants enhances the expression of genes associated with cyclic electron flow pathways in Arabidopsis thaliana, consistent with the higher ATP requirement (relative to NADPH) of photorespiration.

  2. Thermo Wigner operator in thermo field dynamics: its introduction and application

    International Nuclear Information System (INIS)

    Fan Hongyi; Jiang Nianquan

    2008-01-01

    Because in thermo-field dynamics (TFD) the thermo-operator has a neat expression in the thermo-entangled state representation, we need to introduce the thermo-Wigner operator (THWO) in the same representation. We derive the THWO in a direct way, which brings much conveniece to calculating the Wigner functions of thermo states in TFD. We also discuss the condition for existence of a wavefunction corresponding to a given Wigner function in the context of TFD by using the explicit form of the THWO.

  3. Quantum logical states and operators for Josephson-like systems

    International Nuclear Information System (INIS)

    Faoro, Lara; Raffa, Francesco A; Rasetti, Mario

    2006-01-01

    We give a formal algebraic description of Josephson-type quantum dynamical systems, i.e., Hamiltonian systems with a cos θ-like potential term. The two-boson Heisenberg algebra plays for such systems the role that the h(1) algebra does for the harmonic oscillator. A single Josephson junction is selected as a representative of Josephson systems. We construct both logical states (codewords) and logical (gate) operators in the superconductive regime. The codewords are the even and odd coherent states of the two-boson algebra: they are shift-resistant and robust, due to squeezing. The logical operators acting on the qubit codewords are expressed in terms of operators in the enveloping of the two-boson algebra. Such a scheme appears to be relevant for quantum information applications. (letter to the editor)

  4. TRANSFORMACIÓN DE ESQUEMAS MULTIDIMENSIONALES DIFUSOS DESDE EL NIVEL CONCEPTUAL AL NIVEL LÓGICO FUZZY MULTIDIMENSIONAL SCHEMA TRANSFORMATION FROM CONCEPTUAL TO LOGICAL LEVEL

    Directory of Open Access Journals (Sweden)

    Sabina Carrera Sepúlveda

    2010-08-01

    Full Text Available En el ámbito de las bases de datos, diversos métodos han sido propuestos para la generación del diseño lógico de un almacén de datos o data warehouse (DW, por otra parte, existen estudios que permiten el almacenamiento y operación de datos imprecisos o difusos en las bases de datos relacionales. Este artículo presenta una propuesta metodológica con un enfoque arquitectura dirigida por modelos (MDA, la cual permite generar el diseño lógico de un data warehouse difuso (DWD. La técnica utilizada consistió en identificar los elementos básicos del modelado multidimensional (MD que se extienden al manejo de atributos difusos en las medidas a nivel conceptual, a través de la aplicación de una secuencia de transformaciones con el propósito de obtener el diseño lógico multidimensional difuso. Uno de los elementos claves para esta transformación es la extensión del metamodelo common warehouse metamodel (CWM OLAP con estereotipos difusos, considerando que, actualmente no existe un método formal que nos permita realizar este tipo de transformaciones.In the databases field, several methods have been proposed for the generation of the logical design of a data warehouse, on the other hand there are also studies that allow the storage and operation of fuzzy data in relational databases. This paper presents a methodological proposal with an MDA approach, which allows to generate the logical design of a fuzzy DW. The technique was used to identify the basic elements of multidimensional modelling and extends them to manage fuzzy attributes in the measures at a conceptual level, through the application of a sequence of transformations to avoid the generation of a logical fuzzy multidimensionaldesign. A key element for this process is the extension of the CWM OLAP metamodel with fuzzy stereotypes. Currently there is no formal method that allows to realize this kind of transformations.

  5. A Simulation Dashboard to Monitor Cognitive Workload during Dismounted Military Operations

    NARCIS (Netherlands)

    Beurden, M. van; Streefkerk, J.W.; Kamphuis, W.; Jetten, A.; Trijp, S. van; Venrooij, W.; Veldhuijs, G.

    2016-01-01

    The rapid development and adoption of new technologies (i.e. advanced sensor and communication platforms and monitoring devices) changes the way soldiers operate in the field. A concern frequently expressed by soldiers and commanders, is the increasing demand that technology places on the cognitive

  6. Operational quantum theory without predefined time

    International Nuclear Information System (INIS)

    Oreshkov, Ognyan; Cerf, Nicolas J

    2016-01-01

    The standard formulation of quantum theory assumes a predefined notion of time. This is a major obstacle in the search for a quantum theory of gravity, where the causal structure of space-time is expected to be dynamical and fundamentally probabilistic in character. Here, we propose a generalized formulation of quantum theory without predefined time or causal structure, building upon a recently introduced operationally time-symmetric approach to quantum theory. The key idea is a novel isomorphism between transformations and states which depends on the symmetry transformation of time reversal. This allows us to express the time-symmetric formulation in a time-neutral form with a clear physical interpretation, and ultimately drop the assumption of time. In the resultant generalized formulation, operations are associated with regions that can be connected in networks with no directionality assumed for the connections, generalizing the standard circuit framework and the process matrix framework for operations without global causal order. The possible events in a given region are described by positive semidefinite operators on a Hilbert space at the boundary, while the connections between regions are described by entangled states that encode a nontrivial symmetry and could be tested in principle. We discuss how the causal structure of space-time could be understood as emergent from properties of the operators on the boundaries of compact space-time regions. The framework is compatible with indefinite causal order, timelike loops, and other acausal structures. (paper)

  7. Perturbation of self-adjoint operators by Dirac distributions

    International Nuclear Information System (INIS)

    Zorbas, J.

    1980-01-01

    The existence of a family of self-adjoint Hamiltonians H/sub theta/, theta element of [0, 2π), corresponding to the formal expression H 0 +νdelta (x) is shown for a general class of self-adjoint operators H 0 . Expressions for the Green's function and wavefunction corresponding to H/sub theta/ are obtained in terms of the Green's function and wavefunction corresponding to H 0 . Similar results are shown for the perturbation of H 0 by a finite sum of Dirac distributions. A prescription is given for obtaining H/sub theta/ as the strong resolvent limit of a family of momentum cutoff Hamiltonians H/sup N/. The relationship between the scattering theories corresponding to H/sup N/ and H/sub theta/ is examined

  8. Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model.

    Science.gov (United States)

    Koh, Phil-Ok

    2017-06-01

    Diabetes is a major risk factor for stroke and is also associated with worsened outcomes following a stroke. Peroxiredoxin-2 exerts potent neuroprotective effects against oxidative stress. In the present study, we identified altered peroxiredoxin-2 expression in an ischemic stroke model under hyperglycemic conditions. Adult male rats were administrated streptozotocin (40 mg/kg) via intraperitoneal injection to induce diabetes. Middle cerebral artery occlusion (MCAO) was induced surgically 4 weeks after streptozotocin treatment and cerebral cortex tissues were isolated 24 hours after MCAO. Peroxiredoxin-2 expression was evaluated in the cerebral cortex of MCAO-operated animals using a proteomics approach, and was found to be decreased. In addition, the reduction in peroxiredoxin-2 levels was more severe in cerebral ischemia with diabetes compared to animals without diabetes. Reverse-transcriptase PCR and Western blot analyses confirmed the significantly reduced peroxiredoxin-2 expression in MCAO-operated animals under hyperglycemic conditions. It is an accepted fact that peroxiredoxin-2 has antioxidative activity against ischemic injury. Thus, the findings of this study suggest that a more severe reduction in peroxiredoxin-2 under hyperglycemic conditions leads to worsened brain damage during cerebral ischemia with diabetes.

  9. The change of expression configuration affects identity-dependent expression aftereffect but not identity-independent expression aftereffect

    Directory of Open Access Journals (Sweden)

    Miao eSong

    2015-12-01

    Full Text Available The present study examined the influence of expression configuration on cross-identity expression aftereffect. The expression configuration refers to the spatial arrangement of facial features in a face for conveying an emotion, e.g., an open-mouth smile versus a closed-mouth smile. In the first of two experiments, the expression aftereffect is measured using across-identity/cross-expression configuration factorial design. The facial identities of test faces were the same or different from the adaptor, while orthogonally, the expression configurations of those facial identities were also the same or different. The result shows that the change of expression configuration impaired the expression aftereffect when the facial identities of adaptor and tests were the same; however, the impairment effect disappears when facial identities were different, indicating the identity-independent expression representation is more robust to the change of the expression configuration in comparison with the identity-dependent expression representation. In the second experiment, we used schematic line faces as adaptors and real faces as tests to minimize the similarity between the adaptor and tests, which is expected to exclude the contribution from the identity-dependent expression representation to expression aftereffect. The second experiment yields a similar result as the identity-independent expression aftereffect observed in Experiment 1. The findings indicate the different neural sensitivities to expression configuration for identity-dependent and identity-independent expression systems.

  10. Network Completion for Static Gene Expression Data

    Directory of Open Access Journals (Sweden)

    Natsu Nakajima

    2014-01-01

    Full Text Available We tackle the problem of completing and inferring genetic networks under stationary conditions from static data, where network completion is to make the minimum amount of modifications to an initial network so that the completed network is most consistent with the expression data in which addition of edges and deletion of edges are basic modification operations. For this problem, we present a new method for network completion using dynamic programming and least-squares fitting. This method can find an optimal solution in polynomial time if the maximum indegree of the network is bounded by a constant. We evaluate the effectiveness of our method through computational experiments using synthetic data. Furthermore, we demonstrate that our proposed method can distinguish the differences between two types of genetic networks under stationary conditions from lung cancer and normal gene expression data.

  11. Analytical Expressions of Matrix Elements of Physical Quantities for Dirac Oscillator

    Institute of Scientific and Technical Information of China (English)

    LI Ning; JU Guo-Xing; REN Zhong-Zhou

    2004-01-01

    The analytical expressions of the matrix elements for physical quantities are obtained for the Dirac oscillator in two and three spatial dimensions. Their behaviour for the case of operator's square is discussed in details. The twodimensional Dirac oscillator has similar behavior to that for three-dimensional one.

  12. Mapping a mathematical expression onto a Montium ALU using GNU Bison

    NARCIS (Netherlands)

    Rosien, M.A.J.; Smit, Gerardus Johannes Maria

    2004-01-01

    The Montium processing tile [1], [4] contains a number of complex ALUs which can perform many different operations in many different ways. In the Chameleon tool flow [2], it is necessary to automatically determine whether a certain mathematical expression can be mapped onto an ALU and to

  13. Mars Express — how to be fastest to the Red Planet

    Science.gov (United States)

    2003-05-01

    measures 1.5 by 1.8 by 1.4 metres (excluding solar panels), and weighs 1223 kilograms in total. The Beagle-2 lander travels attached to one side of the spacecraft, folded up rather like a very large pocket watch. Arrival at Mars is scheduled for late December this year, when Beagle 2 will land while the orbiter is entering its orbit around Mars. The last activities of an intense launch campaign are taking place in Baikonur at this very moment. Mars Express arrived at the Cosmodrome on 20 March. The spacecraft, fuelled with 457 kilograms of propellant, was mounted on the Soyuz launcher on 24 May in a process that the Russians call ‘marriage’. The whole structure was rolled out to the launch pad on 29 May, four days before launch. The fastest possible trip to Mars One of the reasons scientists had to develop Mars Express so quickly arises from the fact that, this summer, Mars and the Earth will be especially close to each other. Although launch opportunities to go to Mars occur every 26 months - when the Sun, Earth and Mars form a straight line - this year the planets will be at their closest, which happens every 15 to 17 years. On top of that, calculations had shown that the best combination of fuel expenditure and travel time could only be achieved by launching in the period between 23 May and 21 June. The Mars Express team had to work very hard to meet this launch window. As a tribute from one European high-tech organisation to another, Mars Express is carrying a small container of Ferrari red paint to the Red Planet. After the launch Mars Express will separate from the Soyuz Fregat upper stage 90 minutes after liftoff. Then the solar arrays will open and the spacecraft will make contact with ESA’s ground station in New Norcia, Western Australia. Mars Express will be travelling away from Earth at a speed of 3 kilometres per second. A crucial operation at this early stage of the trip will be to release the Beagle-2 launch clamps three days after launch. These clamps

  14. Antiunitary symmetry operators in quantum mechanics

    International Nuclear Information System (INIS)

    Carinena, J.F.; Santander, M.

    1981-01-01

    A criterion to decide that some symmetries of a quantum system must be realized as antiunitary operators is given. It is based on some mathematical theorems about the second cohomology group of the symmetry group when expressed in terms of those of a normal subgroup and the corresponding factor group. It is also shown that this criterion implies that the only possibility for the unitary subgroup in the Galilean case is that generated by the space reflection and the connected component containing the identity; otherwise only massless systems would arise. (author)

  15. Text book of dose calculation for operators

    International Nuclear Information System (INIS)

    Aoyagi, Haruki; Gonda, Kozo

    1979-07-01

    This is a text book of dose calculation for the operators of the reprocessing factory of Power Reactor and Nuclear Fuel Development Corporation. The radiations considered are beta-ray and gamma-ray. The method used is a point attenuation nuclear integral method. Radiation sources are considered as the assemblies of point sources. Dose from each point source is calculated, then, total dose is obtained by the integration for all sources. Attenuation is calculated by considering the attenuation owing to distance and the absorption by absorbers. The build-up factor is introduced for the correction for scattered gamma-ray. The build-up factor is given in a table for various scatterers. The operators are able to calculate dose by themselves. The results of integral calculation expressed with formulas are given in graphs. (Kato, T.)

  16. A program for performing angular integrations for transition operators

    International Nuclear Information System (INIS)

    Froese Fischer, C.; Godefroid, M.R.; Hibbert, A.

    1991-01-01

    The MCHF-MLTPOL program performs the angular integrations necessary for expressing the matrix elements of transition operators, E1, E2, ..., or M1, M2, ..., as linear combinations of radial integrals. All matrix elements for transitions between two lists of configuration states will be evaluated. A limited amount of non-orthogonality is allowed between orbitals of the initial and final state. (orig.)

  17. Pervasive Effects of Aging on Gene Expression in Wild Wolves

    Science.gov (United States)

    Charruau, Pauline; Johnston, Rachel A.; Stahler, Daniel R.; Lea, Amanda; Snyder-Mackler, Noah; Smith, Douglas W.; vonHoldt, Bridgett M.; Cole, Steven W.; Tung, Jenny; Wayne, Robert K.

    2016-01-01

    Abstract Gene expression levels change as an individual ages and responds to environmental conditions. With the exception of humans, such patterns have principally been studied under controlled conditions, overlooking the array of developmental and environmental influences that organisms encounter under conditions in which natural selection operates. We used high-throughput RNA sequencing (RNA-Seq) of whole blood to assess the relative impacts of social status, age, disease, and sex on gene expression levels in a natural population of gray wolves (Canis lupus). Our findings suggest that age is broadly associated with gene expression levels, whereas other examined factors have minimal effects on gene expression patterns. Further, our results reveal evolutionarily conserved signatures of senescence, such as immunosenescence and metabolic aging, between wolves and humans despite major differences in life history and environment. The effects of aging on gene expression levels in wolves exhibit conservation with humans, but the more rapid expression differences observed in aging wolves is evolutionarily appropriate given the species’ high level of extrinsic mortality due to intraspecific aggression. Some expression changes that occur with age can facilitate physical age-related changes that may enhance fitness in older wolves. However, the expression of these ancestral patterns of aging in descendant modern dogs living in highly modified domestic environments may be maladaptive and cause disease. This work provides evolutionary insight into aging patterns observed in domestic dogs and demonstrates the applicability of studying natural populations to investigate the mechanisms of aging. PMID:27189566

  18. Discussion on the entransy expressions of the thermodynamic laws and their applications

    International Nuclear Information System (INIS)

    Cheng, XueTao; Liang, XinGang

    2013-01-01

    In this paper, the entransy expressions of the three thermodynamic laws are discussed. The entransy expression of the first law is that the entransy of any thermodynamic system is in balance. For the second law, the entransy expression for heat transfer is that the entransy flow will never be transported from a low temperature body to a high temperature body automatically and entransy dissipation always exists. The entransy expression for heat-work conversion is that it is impossible for any device to operate in a cycle that receives heat entransy flow from a single reservoir and results in an equivalent amount of work entransy flow. The two entransy expressions of the second law are proved to be equivalent to each other. For the third law, its entransy expression is that it is impossible to achieve the zero entransy for any body through limited processes. With these expressions, the Clausius inequality is proved, and the concept of entransy loss is defined. The application of entransy loss to heat transfer and heat-work conversion is discussed. - Highlights: • The entransy expressions of the three thermodynamic laws are discussed. • The Clausius inequality is proved with the entransy expressions of the laws. • The concept of entransy loss is defined with the entransy expressions of the laws. • Entransy loss can be used to analyze heat transfer and heat-work conversion

  19. Carbon emission from farm operations.

    Science.gov (United States)

    Lal, R

    2004-09-01

    This manuscript is a synthesis of the available information on energy use in farm operations, and its conversion into carbon equivalent (CE). A principal advantage of expressing energy use in terms of carbon (C) emission as kg CE lies in its direct relation to the rate of enrichment of atmospheric concentration of CO2. Synthesis of the data shows that estimates of emissions in kg CE/ha are 2-20 for different tillage operations, 1-1.4 for spraying chemicals, 2-4 for drilling or seeding and 6-12 for combine harvesting. Similarly, estimates of C emissions in kg CE/kg for different fertilizer nutrients are 0.9-1.8 for N, 0.1-0.3 for P2O5, 0.1-0.2 for K20 and 0.03-0.23 for lime. Estimates of C emission in kg CE/kg of active ingredient (a.i.) of different pesticides are 6.3 for herbicides, 5.1 for insecticides and 3.9 for fungicides. Irrigation, lifting water from deep wells and using sprinkling systems, emits 129+/-98 kg CE for applying 25 cm of water and 258+/-195 for 50 cm of water. Emission for different tillage methods are 35.3 kg CE/ha for conventional till, 7.9 kg CE/ha for chisel till or minimum till, and 5.8 kg CE/ha for no-till method of seedbed preparation. In view of the high C costs of major inputs, sustainable management of agricultural ecosystems implies that an output/input ratio, expressed either as gross or net output of C, must be >1 and has an increasing trend over time.

  20. Quantifying HER-2 expression on circulating tumor cells by ACCEPT.

    Directory of Open Access Journals (Sweden)

    Leonie Zeune

    Full Text Available Circulating tumor cells (CTCs isolated from blood can be probed for the expression of treatment targets. Immunofluorescence is often used for both the enumeration of CTC and the determination of protein expression levels related to treatment targets. Accurate and reproducible assessment of such treatment target expression levels is essential for their use in the clinic. To enable this, an open source image analysis program named ACCEPT was developed in the EU-FP7 CTCTrap and CANCER-ID programs. Here its application is shown on a retrospective cohort of 132 metastatic breast cancer patients from which blood samples were processed by CellSearch® and stained for HER-2 expression as additional marker. Images were digitally stored and reviewers identified a total of 4084 CTCs. CTC's HER-2 expression was determined in the thumbnail images by ACCEPT. 150 of these images were selected and sent to six independent investigators to score the HER-2 expression with and without ACCEPT. Concordance rate of the operators' scoring results for HER-2 on CTCs was 30% and could be increased using the ACCEPT tool to 51%. Automated assessment of HER-2 expression by ACCEPT on 4084 CTCs of 132 patients showed 8 (6.1% patients with all CTCs expressing HER-2, 14 (10.6% patients with no CTC expressing HER-2 and 110 (83.3% patients with CTCs showing a varying HER-2 expression level. In total 1576 CTCs were determined HER-2 positive. We conclude that the use of image analysis enables a more reproducible quantification of treatment targets on CTCs and leads the way to fully automated and reproducible approaches.

  1. Quantifying HER-2 expression on circulating tumor cells by ACCEPT.

    Science.gov (United States)

    Zeune, Leonie; van Dalum, Guus; Decraene, Charles; Proudhon, Charlotte; Fehm, Tanja; Neubauer, Hans; Rack, Brigitte; Alunni-Fabbroni, Marianna; Terstappen, Leon W M M; van Gils, Stephan A; Brune, Christoph

    2017-01-01

    Circulating tumor cells (CTCs) isolated from blood can be probed for the expression of treatment targets. Immunofluorescence is often used for both the enumeration of CTC and the determination of protein expression levels related to treatment targets. Accurate and reproducible assessment of such treatment target expression levels is essential for their use in the clinic. To enable this, an open source image analysis program named ACCEPT was developed in the EU-FP7 CTCTrap and CANCER-ID programs. Here its application is shown on a retrospective cohort of 132 metastatic breast cancer patients from which blood samples were processed by CellSearch® and stained for HER-2 expression as additional marker. Images were digitally stored and reviewers identified a total of 4084 CTCs. CTC's HER-2 expression was determined in the thumbnail images by ACCEPT. 150 of these images were selected and sent to six independent investigators to score the HER-2 expression with and without ACCEPT. Concordance rate of the operators' scoring results for HER-2 on CTCs was 30% and could be increased using the ACCEPT tool to 51%. Automated assessment of HER-2 expression by ACCEPT on 4084 CTCs of 132 patients showed 8 (6.1%) patients with all CTCs expressing HER-2, 14 (10.6%) patients with no CTC expressing HER-2 and 110 (83.3%) patients with CTCs showing a varying HER-2 expression level. In total 1576 CTCs were determined HER-2 positive. We conclude that the use of image analysis enables a more reproducible quantification of treatment targets on CTCs and leads the way to fully automated and reproducible approaches.

  2. Conformal four point functions and the operator product expansion

    International Nuclear Information System (INIS)

    Dolan, F.A.; Osborn, H.

    2001-01-01

    Various aspects of the four point function for scalar fields in conformally invariant theories are analysed. This depends on an arbitrary function of two conformal invariants u,v. A recurrence relation for the function corresponding to the contribution of an arbitrary spin field in the operator product expansion to the four point function is derived. This is solved explicitly in two and four dimensions in terms of ordinary hypergeometric functions of variables z,x which are simply related to u,v. The operator product expansion analysis is applied to the explicit expressions for the four point function found for free scalar, fermion and vector field theories in four dimensions. The results for four point functions obtained by using the AdS/CFT correspondence are also analysed in terms of functions related to those appearing in the operator product discussion

  3. Linear inequalities and overlap bounds: a novel use of an operator inequality

    International Nuclear Information System (INIS)

    Cohen, M.; Leopold, J.G.

    1976-01-01

    Bounds to overlap integrals are obtained by an operator inequality technique. The formulation involves a set of linear inequalities with several overlap integrals as unknowns. The 'solution' of this set of inequalities leads to bound expressions which complement those of other workers. (author)

  4. 77 FR 52599 - Drawbridge Operation Regulation; Elizabeth River, Eastern Branch, Norfolk, VA

    Science.gov (United States)

    2012-08-30

    ...; we anticipate less vehicular traffic congestion between 9 a.m. and 3 p.m., while causing fewer... expressed concerns about unscheduled openings that caused vehicular traffic congestion. The unscheduled... operating procedures appear to have reduced vehicular traffic congestion while still providing for the...

  5. Factors limiting SOS expression in log-phase cells of Escherichia coli.

    Science.gov (United States)

    Massoni, Shawn C; Leeson, Michael C; Long, Jarukit Edward; Gemme, Kristin; Mui, Alice; Sandler, Steven J

    2012-10-01

    In Escherichia coli, RecA-single-stranded DNA (RecA-ssDNA) filaments catalyze DNA repair, recombination, and induction of the SOS response. It has been shown that, while many (15 to 25%) log-phase cells have RecA filaments, few (about 1%) are induced for SOS. It is hypothesized that RecA's ability to induce SOS expression in log-phase cells is repressed because of the potentially detrimental effects of SOS mutagenesis. To test this, mutations were sought to produce a population where the number of cells with SOS expression more closely equaled the number of RecA filaments. Here, it is shown that deleting radA (important for resolution of recombination structures) and increasing recA transcription 2- to 3-fold with a recAo1403 operator mutation act independently to minimally satisfy this condition. This allows 24% of mutant cells to have elevated levels of SOS expression, a percentage similar to that of cells with RecA-green fluorescent protein (RecA-GFP) foci. In an xthA (exonuclease III gene) mutant where there are 3-fold more RecA loading events, recX (a destabilizer of RecA filaments) must be additionally deleted to achieve a population of cells where the percentage having elevated SOS expression (91%) nearly equals the percentage with at least one RecA-GFP focus (83%). It is proposed that, in the xthA mutant, there are three independent mechanisms that repress SOS expression in log-phase cells. These are the rapid processing of RecA filaments by RadA, maintaining the concentration of RecA below a critical level, and the destabilizing of RecA filaments by RecX. Only the first two mechanisms operate independently in a wild-type cell.

  6. Expression of Cellular Isoform of Prion Protein on the Surface of Peripheral Blood Lymphocytes Among Women Exposed to Low Doses of Ionizing Radiation

    International Nuclear Information System (INIS)

    Klucinski, P.; Martirosian, G.; Mazur, B.; Kaufman, J.; Hrycek, A.; Masluch, E.; Cieslik, P.

    2007-01-01

    Ionizing radiation affect the expression of adhesive and co-stimulation molecules in lymphocytes. The objective of this study was to determinate the effect of low doses of ionizing radiation on the expression of prion protein PrPc on the surface peripheral blood lymphocytes in the women operating X-ray equipment. In female workers and persons of the control group the PrPc expression on CD3 (T-lymphocytes), Cd4 (T-helper), CD8 (T-cytotoxic) and CD19 (B- lymphocytes), were tested. We conclude that in women operating X-ray equipment the relationship between low doses of ionizing radiation and expression of PrPc on lymphocytes does exist concerning CD3, CD4 and CD lymphocytes. (author)

  7. Expression of Plant Receptor Kinases in Tobacco BY-2 Cells.

    Science.gov (United States)

    Shinohara, Hidefumi; Matsubayashi, Yoshikatsu

    2017-01-01

    Although more than 600 single-transmembrane receptor kinase genes have been found in the Arabidopsis genome, only a few of them have known physiological functions, and even fewer plant receptor kinases have known specific ligands. Ligand-binding analysis must be operated using the functionally expressed receptor form. However, the relative abundance of native receptor kinase molecules in the plasma membrane is often quite low. Here, we present a method for stable and functional expression of plant receptor kinases in tobacco BY-2 cells that allows preparation of microsomal fractions containing the receptor. This procedure provides a sufficient amount of receptor proteins while maintaining its ligand-binding activities.

  8. Simple and Realistic Data Generation

    DEFF Research Database (Denmark)

    Pedersen, Kenneth Houkjær; Torp, Kristian; Wind, Rico

    2006-01-01

    This paper presents a generic, DBMS independent, and highly extensible relational data generation tool. The tool can efficiently generate realistic test data for OLTP, OLAP, and data streaming applications. The tool uses a graph model to direct the data generation. This model makes it very simple...... to generate data even for large database schemas with complex inter- and intra table relationships. The model also makes it possible to generate data with very accurate characteristics....

  9. A correlation study of the expression of resistin and glycometabolism in muscle tissue after traumatic brain injury in rats

    Institute of Scientific and Technical Information of China (English)

    Jin Peng; Zhu Lielie; Zhang Jiasheng; Xie Songling; Pan Da; Wen Hao; Meng Weiyang

    2014-01-01

    Objective:To investigate the expression pattern of resistin (RSTN) in skeletal muscle tissue and its influence on glycometabolism in rats with traumatic brain injury (TBI).Methods:Seventy-eight SD rats were randomly divided into traumatic group (n=36),RSTN group (n=36) and sham operation group (n=6).Fluid percussion TBI model was developed in traumatic and RSTN groups and the latter received additional 1 mg RSTN antibody treatment for each rat.At respectively 12 h,24 h,72 h,1 w,2 w,and 4 w after operation,venous blood was collected and the right hind leg skeletal muscle tissue was sampled.We used real-time PCR to determine mRNA expression of RSTN in skeletal muscles,western blot to determine RSTN protein expression and ELISA to assess serum insulin as well as fasting blood glucose (FBG) levels.Calculation of the quantitative insulin sensitivity check index (Q value) was also conducted.The above mentioned indicators and their correction were statistically analyzed.Results:Compared with sham operation group,the RSTN expression in the skeletal muscle as well as serum insulin and FBG levels revealed significant elevation (P<0.05),and reduced Q value (P<0.05) in traumatic group.Single factor linear correlation analysis showed a significant negative correlation between RSTN expression and Q values (P<0.001) in traumatic group.Conclusion:The expression of RSTN has been greatly increased in the muscular tissue of TBI rats and it was closely related to the index of glycometabolism.RSTN may play an important role in the process of insulin resistance after TBI.

  10. A Survey on Operator Monotonicity, Operator Convexity, and Operator Means

    Directory of Open Access Journals (Sweden)

    Pattrawut Chansangiam

    2015-01-01

    Full Text Available This paper is an expository devoted to an important class of real-valued functions introduced by Löwner, namely, operator monotone functions. This concept is closely related to operator convex/concave functions. Various characterizations for such functions are given from the viewpoint of differential analysis in terms of matrix of divided differences. From the viewpoint of operator inequalities, various characterizations and the relationship between operator monotonicity and operator convexity are given by Hansen and Pedersen. In the viewpoint of measure theory, operator monotone functions on the nonnegative reals admit meaningful integral representations with respect to Borel measures on the unit interval. Furthermore, Kubo-Ando theory asserts the correspondence between operator monotone functions and operator means.

  11. Quantitative gene expression underlying 18f-fluorodeoxyglucose uptake in colon cancer

    DEFF Research Database (Denmark)

    Engelmann, Bodil E.; Binderup, Tina; Kjær, Andreas

    2015-01-01

    Background: Positron emission tomography (PET) with the glucose analogue 18F-fluorodeoxyglucose (FDG) is widely used in oncologic imaging. This study examines the molecular mechanism underlying the detection of colon cancer (CC) by FDG-PET. Methods: Pre-operative PET/CT scans and tissue samples....... Mean gene expression levels of GLUT1, HK2, ki67, HIF1α, VEGF and CaIX, but not HK1, were significantly higher in primary tumours than in surrounding normal colonic mucosa. Linear regressions pairing tumour SUVmax with gene expression levels showed significant correlations between SUVmax and HK2, ki67...

  12. Identification of Error Types in Preservice Teachers' Attempts to Create Fraction Story Problems for Specified Operations

    Science.gov (United States)

    McAllister, Cheryl J.; Beaver, Cheryl

    2012-01-01

    The purpose of this research was to determine if recognizable error types exist in the work of preservice teachers required to create story problems for specific fraction operations. Students were given a particular single-operation fraction expression and asked to do the calculation and then create a story problem that would require the use of…

  13. The Launch Systems Operations Cost Model

    Science.gov (United States)

    Prince, Frank A.; Hamaker, Joseph W. (Technical Monitor)

    2001-01-01

    One of NASA's primary missions is to reduce the cost of access to space while simultaneously increasing safety. A key component, and one of the least understood, is the recurring operations and support cost for reusable launch systems. In order to predict these costs, NASA, under the leadership of the Independent Program Assessment Office (IPAO), has commissioned the development of a Launch Systems Operations Cost Model (LSOCM). LSOCM is a tool to predict the operations & support (O&S) cost of new and modified reusable (and partially reusable) launch systems. The requirements are to predict the non-recurring cost for the ground infrastructure and the recurring cost of maintaining that infrastructure, performing vehicle logistics, and performing the O&S actions to return the vehicle to flight. In addition, the model must estimate the time required to cycle the vehicle through all of the ground processing activities. The current version of LSOCM is an amalgamation of existing tools, leveraging our understanding of shuttle operations cost with a means of predicting how the maintenance burden will change as the vehicle becomes more aircraft like. The use of the Conceptual Operations Manpower Estimating Tool/Operations Cost Model (COMET/OCM) provides a solid point of departure based on shuttle and expendable launch vehicle (ELV) experience. The incorporation of the Reliability and Maintainability Analysis Tool (RMAT) as expressed by a set of response surface model equations gives a method for estimating how changing launch system characteristics affects cost and cycle time as compared to today's shuttle system. Plans are being made to improve the model. The development team will be spending the next few months devising a structured methodology that will enable verified and validated algorithms to give accurate cost estimates. To assist in this endeavor the LSOCM team is part of an Agency wide effort to combine resources with other cost and operations professionals to

  14. Stream Processing Using Grammars and Regular Expressions

    DEFF Research Database (Denmark)

    Rasmussen, Ulrik Terp

    disambiguation. The first algorithm operates in two passes in a semi-streaming fashion, using a constant amount of working memory and an auxiliary tape storage which is written in the first pass and consumed by the second. The second algorithm is a single-pass and optimally streaming algorithm which outputs...... as much of the parse tree as is semantically possible based on the input prefix read so far, and resorts to buffering as many symbols as is required to resolve the next choice. Optimality is obtained by performing a PSPACE-complete pre-analysis on the regular expression. In the second part we present...... Kleenex, a language for expressing high-performance streaming string processing programs as regular grammars with embedded semantic actions, and its compilation to streaming string transducers with worst-case linear-time performance. Its underlying theory is based on transducer decomposition into oracle...

  15. Seismic-load-induced human errors and countermeasures using computer graphics in plant-operator communication

    International Nuclear Information System (INIS)

    Hara, Fumio

    1988-01-01

    This paper remarks the importance of seismic load-induced human errors in plant operation by delineating the characteristics of the task performance of human beings under seismic loads. It focuses on man-machine communication via multidimensional data like that conventionally displayed on large panels in a plant control room. It demonstrates a countermeasure to human errors using a computer graphics technique that conveys the global state of the plant operation to operators through cartoon-like, colored graphs in the form of faces that, with different facial expressions, show the plant safety status. (orig.)

  16. Closure of the operator product expansion in the non-unitary bootstrap

    Energy Technology Data Exchange (ETDEWEB)

    Esterlis, Ilya [Stanford Institute for Theoretical Physics, Stanford University,Via Pueblo, Stanford, CA 94305 (United States); Fitzpatrick, A. Liam [Department of Physics, Boston University,Commonwealth Ave, Boston, MA, 02215 (United States); Ramirez, David M. [Stanford Institute for Theoretical Physics, Stanford University,Via Pueblo, Stanford, CA 94305 (United States)

    2016-11-07

    We use the numerical conformal bootstrap in two dimensions to search for finite, closed sub-algebras of the operator product expansion (OPE), without assuming unitarity. We find the minimal models as special cases, as well as additional lines of solutions that can be understood in the Coulomb gas formalism. All the solutions we find that contain the vacuum in the operator algebra are cases where the external operators of the bootstrap equation are degenerate operators, and we argue that this follows analytically from the expressions in http://arxiv.org/abs/1202.4698 for the crossing matrices of Virasoro conformal blocks. Our numerical analysis is a special case of the “Gliozzi” bootstrap method, and provides a simpler setting in which to study technical challenges with the method. In the supplementary material, we provide a Mathematica notebook that automates the calculation of the crossing matrices and OPE coefficients for degenerate operators using the formulae of Dotsenko and Fateev.

  17. Explicit analytical expression for the condition number of polynomials in power form

    Science.gov (United States)

    Rack, Heinz-Joachim

    2017-07-01

    In his influential papers [1-3] W. Gautschi has defined and reshaped the condition number κ∞ of polynomials Pn of degree ≤ n which are represented in power form on a zero-symmetric interval [-ω, ω]. Basically, κ∞ is expressed as the product of two operator norms: an explicit factor times an implicit one (the l∞-norm of the coefficient vector of the n-th Chebyshev polynomial of the first kind relative to [-ω, ω]). We provide a new proof, economize the second factor and express it by an explicit analytical formula.

  18. On the marginally relevant operator in z=2 Lifshitz holography

    International Nuclear Information System (INIS)

    Holsheimer, Kristian

    2014-01-01

    We study holographic renormalization and RG flow in a strongly-coupled Lifshitz-type theory in 2+1 dimensions with dynamical exponent z=2. The bottom-up gravity dual we use is 3+1 dimensional Einstein gravity coupled to a massive vector field. This model contains a marginally relevant operator around the Lifshitz fixed point. We show how holographic renormalization works in the presence of this marginally relevant operator without the need to introduce explicitly cutoff-dependent counterterms. A simple closed-form expression is found for the renormalized on-shell action. We also discuss how asymptotically Lifshitz geometries flow to AdS in the interior due to the marginally relevant operator. We study the behavior of the renormalized entanglement entropy and confirm that it decreases monotonically along the Lifshitz-to-AdS RG flow

  19. Dimensional modeling: beyond data processing constraints.

    Science.gov (United States)

    Bunardzic, A

    1995-01-01

    The focus of information processing requirements is shifting from the on-line transaction processing (OLTP) issues to the on-line analytical processing (OLAP) issues. While the former serves to ensure the feasibility of the real-time on-line transaction processing (which has already exceeded a level of up to 1,000 transactions per second under normal conditions), the latter aims at enabling more sophisticated analytical manipulation of data. The OLTP requirements, or how to efficiently get data into the system, have been solved by applying the Relational theory in the form of Entity-Relation model. There is presently no theory related to OLAP that would resolve the analytical processing requirements as efficiently as Relational theory provided for the transaction processing. The "relational dogma" also provides the mathematical foundation for the Centralized Data Processing paradigm in which mission-critical information is incorporated as 'one and only one instance' of data, thus ensuring data integrity. In such surroundings, the information that supports business analysis and decision support activities is obtained by running predefined reports and queries that are provided by the IS department. In today's intensified competitive climate, businesses are finding that this traditional approach is not good enough. The only way to stay on top of things, and to survive and prosper, is to decentralize the IS services. The newly emerging Distributed Data Processing, with its increased emphasis on empowering the end user, does not seem to find enough merit in the relational database model to justify relying upon it. Relational theory proved too rigid and complex to accommodate the analytical processing needs. In order to satisfy the OLAP requirements, or how to efficiently get the data out of the system, different models, metaphors, and theories have been devised. All of them are pointing to the need for simplifying the highly non-intuitive mathematical constraints found

  20. Sonic hedgehog (SHH) and glioblastoma-2 (Gli-2) expressions are associated with poor jaundice-free survival in biliary atresia.

    Science.gov (United States)

    Jung, Hae Yoen; Jing, Jin; Lee, Kyoung Bun; Jang, Ja-June

    2015-03-01

    Biliary atresia (BA) causes biliary obstruction in neonates. Although the Kasai operation can successfully treat certain BA cases, many patients exhibit recurrent jaundice and secondary biliary cirrhosis requiring liver transplantation. Consequently, studies of the prognostic factors of the Kasai operation are needed. Accordingly, sonic hedgehog (SHH) pathway expression at the extrahepatic bile duct (EHBD), an important bile duct repair mechanism, will be investigated via immunohistochemistry in patients with BA to examine the association with post-Kasai operation prognosis. Fifty-seven EHBD specimens were obtained during Kasai operations from 1992 to 2009. The SHH, patched (PTCH), and glioblastoma-2 (Gli-2) immunohistochemical staining results were analyzed quantitatively. Overall, 57.9% of patients had bile flow normalization after the Kasai operation; 43.1% did not. High preoperative serum total bilirubin, direct bilirubin, and aspartate aminotransferase levels were associated with sustained jaundice post-Kasai operation, as was an age ≥65days at the time of surgery (all pjaundice relapse. Strong Gli-2 and SHH expression in the EHBD might be a poor prognostic factor in Kasai operation-treated patients with BA. Copyright © 2015 Elsevier Inc. All rights reserved.

  1. Expression

    Directory of Open Access Journals (Sweden)

    Wang-Xia Wang

    2014-02-01

    Full Text Available The miR-15/107 family comprises a group of 10 paralogous microRNAs (miRNAs, sharing a 5′ AGCAGC sequence. These miRNAs have overlapping targets. In order to characterize the expression of miR-15/107 family miRNAs, we employed customized TaqMan Low-Density micro-fluid PCR-array to investigate the expression of miR-15/107 family members, and other selected miRNAs, in 11 human tissues obtained at autopsy including the cerebral cortex, frontal cortex, primary visual cortex, thalamus, heart, lung, liver, kidney, spleen, stomach and skeletal muscle. miR-103, miR-195 and miR-497 were expressed at similar levels across various tissues, whereas miR-107 is enriched in brain samples. We also examined the expression patterns of evolutionarily conserved miR-15/107 miRNAs in three distinct primary rat brain cell preparations (enriched for cortical neurons, astrocytes and microglia, respectively. In primary cultures of rat brain cells, several members of the miR-15/107 family are enriched in neurons compared to other cell types in the central nervous system (CNS. In addition to mature miRNAs, we also examined the expression of precursors (pri-miRNAs. Our data suggested a generally poor correlation between the expression of mature miRNAs and their precursors. In summary, we provide a detailed study of the tissue and cell type-specific expression profile of this highly expressed and phylogenetically conserved family of miRNA genes.

  2. Operator theory, operator algebras and applications

    CERN Document Server

    Lebre, Amarino; Samko, Stefan; Spitkovsky, Ilya

    2014-01-01

    This book consists of research papers that cover the scientific areas of the International Workshop on Operator Theory, Operator Algebras and Applications, held in Lisbon in September 2012. The volume particularly focuses on (i) operator theory and harmonic analysis (singular integral operators with shifts; pseudodifferential operators, factorization of almost periodic matrix functions; inequalities; Cauchy type integrals; maximal and singular operators on generalized Orlicz-Morrey spaces; the Riesz potential operator; modification of Hadamard fractional integro-differentiation), (ii) operator algebras (invertibility in groupoid C*-algebras; inner endomorphisms of some semi group, crossed products; C*-algebras generated by mappings which have finite orbits; Folner sequences in operator algebras; arithmetic aspect of C*_r SL(2); C*-algebras of singular integral operators; algebras of operator sequences) and (iii) mathematical physics (operator approach to diffraction from polygonal-conical screens; Poisson geo...

  3. A Two-Pass Exact Algorithm for Selection on Parallel Disk Systems.

    Science.gov (United States)

    Mi, Tian; Rajasekaran, Sanguthevar

    2013-07-01

    Numerous OLAP queries process selection operations of "top N", median, "top 5%", in data warehousing applications. Selection is a well-studied problem that has numerous applications in the management of data and databases since, typically, any complex data query can be reduced to a series of basic operations such as sorting and selection. The parallel selection has also become an important fundamental operation, especially after parallel databases were introduced. In this paper, we present a deterministic algorithm Recursive Sampling Selection (RSS) to solve the exact out-of-core selection problem, which we show needs no more than (2 + ε ) passes ( ε being a very small fraction). We have compared our RSS algorithm with two other algorithms in the literature, namely, the Deterministic Sampling Selection and QuickSelect on the Parallel Disks Systems. Our analysis shows that DSS is a (2 + ε )-pass algorithm when the total number of input elements N is a polynomial in the memory size M (i.e., N = M c for some constant c ). While, our proposed algorithm RSS runs in (2 + ε ) passes without any assumptions. Experimental results indicate that both RSS and DSS outperform QuickSelect on the Parallel Disks Systems. Especially, the proposed algorithm RSS is more scalable and robust to handle big data when the input size is far greater than the core memory size, including the case of N ≫ M c .

  4. Enhanced insulin-like growth factor I gene expression in regenerating rat pancreas

    International Nuclear Information System (INIS)

    Smith, F.E.; Rosen, K.M.; Villa-Komaroff, L.; Weir, G.C.; Bonner-Weir, S.

    1991-01-01

    Insulin-like growth factor I (IGF-I) mRNA expression was studied after 90% partial pancreatectomy in the rat to determine whether IGF-I was associated with pancreatic regeneration. The level of IGF-I mRNA was maximally increased (4-fold above control value) 3 days after pancreatectomy, but thereafter gradually decreased, returning to control levels by 14 days after surgery. By in situ hybridization, IGF-I mRNA in both pancreatectomized and sham-operated rats was localized to capillary endothelial cells, indicating that this is the site of IGF-I expression in the normal rat pancreas. However, enhanced IGF-I mRNA expression was localized to focal areas of regeneration unique to pancreatectomized rats. In these areas, epithelial cells of proliferating ductules and individual connective tissue cells expressed IGF-I, suggesting that IGF-I may play an important role in the growth or differentiation of pancreatic tissue

  5. Enhanced insulin-like growth factor I gene expression in regenerating rat pancreas

    Energy Technology Data Exchange (ETDEWEB)

    Smith, F.E.; Rosen, K.M.; Villa-Komaroff, L.; Weir, G.C.; Bonner-Weir, S. (E. P. Joslin Research Laboratory, Joslin Diabetes Center, Harvard Medical School, Boston, MA (USA))

    1991-07-15

    Insulin-like growth factor I (IGF-I) mRNA expression was studied after 90% partial pancreatectomy in the rat to determine whether IGF-I was associated with pancreatic regeneration. The level of IGF-I mRNA was maximally increased (4-fold above control value) 3 days after pancreatectomy, but thereafter gradually decreased, returning to control levels by 14 days after surgery. By in situ hybridization, IGF-I mRNA in both pancreatectomized and sham-operated rats was localized to capillary endothelial cells, indicating that this is the site of IGF-I expression in the normal rat pancreas. However, enhanced IGF-I mRNA expression was localized to focal areas of regeneration unique to pancreatectomized rats. In these areas, epithelial cells of proliferating ductules and individual connective tissue cells expressed IGF-I, suggesting that IGF-I may play an important role in the growth or differentiation of pancreatic tissue.

  6. Automated and Adaptive Mission Planning for Orbital Express

    Science.gov (United States)

    Chouinard, Caroline; Knight, Russell; Jones, Grailing; Tran, Daniel; Koblick, Darin

    2008-01-01

    The Orbital Express space mission was a Defense Advanced Research Projects Agency (DARPA) lead demonstration of on-orbit satellite servicing scenarios, autonomous rendezvous, fluid transfers of hydrazine propellant, and robotic arm transfers of Orbital Replacement Unit (ORU) components. Boeing's Autonomous Space Transport Robotic Operations (ASTRO) vehicle provided the servicing to the Ball Aerospace's Next Generation Serviceable Satellite (NextSat) client. For communication opportunities, operations used the high-bandwidth ground-based Air Force Satellite Control Network (AFSCN) along with the relatively low-bandwidth GEO-Synchronous space-borne Tracking and Data Relay Satellite System (TDRSS) network. Mission operations were conducted out of the RDT&E Support Complex (RSC) at the Kirtland Air Force Base in New Mexico. All mission objectives were met successfully: The first of several autonomous rendezvous was demonstrated on May 5, 2007; autonomous free-flyer capture was demonstrated on June 22, 2007; the fluid and ORU transfers throughout the mission were successful. Planning operations for the mission were conducted by a team of personnel including Flight Directors, who were responsible for verifying the steps and contacts within the procedures, the Rendezvous Planners who would compute the locations and visibilities of the spacecraft, the Scenario Resource Planners (SRPs), who were concerned with assignment of communications windows, monitoring of resources, and sending commands to the ASTRO spacecraft, and the Mission planners who would interface with the real-time operations environment, process planning products and coordinate activities with the SRP. The SRP position was staffed by JPL personnel who used the Automated Scheduling and Planning ENvironment (ASPEN) to model and enforce mission and satellite constraints. The lifecycle of a plan began three weeks outside its execution on-board. During the planning timeframe, many aspects could change the plan

  7. Data Cubes Integration in Spatial OLAP for Agricultural Commodities

    Science.gov (United States)

    Putri, A. I.; Sitanggang, I. S.

    2017-03-01

    Ministry of Agriculture Indonesia collects data of agricultural commodities in Indonesia in the annual period. Agricultural commodities data include food crops, horticulture, plantations, and livestock. The data are available in the spreadsheet format. This study developed data cubes for food crops, plantations, and livestock using the galaxy schema of data warehouse and integrated the data cubes into the SOLAP Horticulture using SpagoBI. SOLAP is useful for data analysis and data visualization. The application displays agricultural commodities data in form of crosstab and chart. This study also developed the location intelligence module that visualizes agricultural commodities data on the map. The system was tested using the black box approach. The result showed that main functions including roll up, drill down, slice, dice, and pivot work properly. This application is expected to enable users to easily obtain data summaries of agricultural commodities.

  8. FX enzyme and GDP-L-Fuc transporter expression in colorectal cancer.

    Science.gov (United States)

    Villar-Portela, Susana; Muinelo-Romay, Laura; Cuevas, Elisa; Gil-Martín, Emilio; Fernández-Briera, Almudena

    2013-08-01

    Fucosylation is regulated by fucosyltransferases, the guanosine diphosphate-L-fucose (GDP-L-Fuc) synthetic pathway, and the GDP-L-fucose transporter (GDP-L-Fuc Tr). We have reported previously an increased level of α(1,6)fucosyltransferase activity and expression in colorectal cancer (CRC). The present study aimed to analyse the expression profiles of the FX enzyme and GDP-L-Fuc Tr in a cohort of operated CRC patients to elucidate their role in α(1,6)fucosylation in this neoplasm. We assessed the immunohistochemical expression of FX and GDP-L-Fuc Tr in a series of tumour samples and healthy tissues from CRC specimens. FX expression was observed in 58 of 91 (63.7%) tumours and 23 of 28 (82.1%) corresponding healthy samples. GDP-L-Fuc Tr expression was detected in 86 of 102 (84.3%) colorectal tumours, and 13 of 27 (48.1%) healthy tissue specimens. The expression of GDP-L-Fuc Tr was statistically higher in tumours than in healthy tissues (P GDP-L-Fuc Tr expression in tumour samples (P = 0.003). GDP-L-Fuc Tr overexpression in the tumour tissue of CRC patients suggests that GDP-L-Fuc transport to the Golgi apparatus may be an important factor associated with increased α(1,6)fucosylation in CRC. © 2013 John Wiley & Sons Ltd.

  9. Altered neurotransmitter expression profile in the ganglionic bowel in Hirschsprung's disease.

    Science.gov (United States)

    Coyle, David; O'Donnell, Anne Marie; Gillick, John; Puri, Prem

    2016-05-01

    Despite having optimal pull-through (PT) surgery for Hirschsprung's disease (HSCR), many patients experience persistent bowel symptoms with no mechanical/histopathological cause. Murine models of HSCR suggest that expression of key neurotransmitters is unbalanced proximal to the aganglionic colonic segment. We aimed to investigate expression of key enteric neurotransmitters in the colon of children with HSCR. Full-length PT specimens were collected fresh from children with HSCR (n=10). Control specimens were collected at colostomy closure from children with anorectal malformation (n=8). The distributions of neuronal nitric oxide synthase (nNOS), choline acetyltransferase (ChAT), vasoactive intestinal peptide (VIP), and substance P (SP) were evaluated using immunofluorescence and confocal microscopy. Neurotransmitter quantification was with Western blot analysis. ChAT expression was high in aganglionic bowel and transition zone but reduced in ganglionic bowel in HSCR relative to controls. Conversely, nNOS expression was markedly reduced in aganglionic bowel but high in ganglionic bowel in HSCR relative to controls. VIP expression was similar in ganglionic HSCR and control colon. SP expression was similar in all tissue types. Imbalance of key excitatory and inhibitory neurotransmitters in the ganglionic bowel in HSCR may explain the basis of bowel dysmotility after an optimal pull-through operation in some patients. Copyright © 2016 Elsevier Inc. All rights reserved.

  10. Rear Operations Group medicine: a pilot study of psychological decompression in a Rear Operations Group during Operation HERRICK 14.

    Science.gov (United States)

    Nimenko, Wasyl; Simpson, R G

    2014-12-01

    To investigate group activity psychological decompression (GAPD) in a Rear Operations Group. Provision of military archaeological exercises for a Rear Operations Group's medical centre patients during Op HERRICK 14 with analysis of before and after Patient Health Questionnaires (PHQ), Work and Social Adjustment Scales, generalised anxiety disorder (GAD) 7 Anxiety, Audit Questionnaire and Impact of Events Scale Revised and analysis of interviews with supervisors and soldiers. Soldiers reported a mean of 13%-38% improvement across the self-reported domains. The civilian archaeologists reported improvements in self-esteem, morale and team-working. 10 out of 24 soldiers have expressed an interest to pursue archaeology further; eight soldiers disclosed mental health issues for the first time, four of whom required mental health referral. GAPD can help early-returned soldiers in reducing symptoms of anxiety, depression, isolation and psychological traumatic symptoms. It also helps to increase perception of their ability to work and socialise as a team and help them to an early return to work. It can provide soldiers with the opportunity to approach their supervisors in an informal manner and help in early detection of mental health problems. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  11. [Expression of connective tissue growth factor in cardiomyocyte of young rats with heart failure and benazepril intervention].

    Science.gov (United States)

    Zhang, Qin; Yi, Qi-jian; Qian, Yong-ru; Li, Rong; Deng, Bing; Wang, Qiao

    2006-10-01

    Ventricular remodeling is an important pathologic progress in almost all end stage heart failure (HF), and it is characterized by ventricular thickening and cardiac fibrosis with poor prognosis. The connective tissue growth factor (CTGF), a new growth factor with multi-function, has an important role in fibrosis of tissue and organs. It has been demonstrated that angiotensin-converting enzyme inhibitor (ACEI) can prevent the development of cardiomyocyte from remodeling and improve cardiac function. Researchers try to test the hypothesis that cardiac function improvement attributable to ACEI is associated with inhibiting expression of CTGF in patients with HF. The aim of this study was to observe changes in CTGF expression in cardiomyocyte of young rats with HF and effect of benazepril on CTGF. The animal model of HF was established by constriction of abdominal aorta. Five weeks old rats were randomly divided into 3 groups after 6 weeks of operation: (1) HF group without treatment (n = 15); (2) HF group where rats were treated with benazepril (n = 15); (3) sham-operated group (n = 15) where rats were administered benazepril through direct gastric gavage. After 4 weeks of treatment, the high frequency ultrasound was performed. The expression of CTGF was detected by immunohistochemistry and semi-quantative reverse transcription-polymerase chain reaction. Compared with the sham-operated group, left ventricular diastolic dimension (LVEDD), left ventricular systolic dimension (LVESD), interventricular septal thickness at end-diastole (IVSTd), interventricular septal thickness at end-systole (IVSTs), left ventricular posterior wall thickness at end-diastole (LVPWTd), left ventricular posterior wall thickness at end-systole (LVPWTs), left ventricular relative weight (LVRW), and right ventricular relative weight (RVRW) were all increased (P benazepril when compared with HF group without treatment. LVESD, IVSTd, IVSTs, LVPWTd, LVPWTs, LVRW and RVRW were higher (P benazepril

  12. Learning Gene Expression Through Modelling and Argumentation. A Case Study Exploring the Connections Between the Worlds of Knowledge

    Science.gov (United States)

    Puig, Blanca; Ageitos, Noa; Jiménez-Aleixandre, María Pilar

    2017-12-01

    There is emerging interest on the interactions between modelling and argumentation in specific contexts, such as genetics learning. It has been suggested that modelling might help students understand and argue on genetics. We propose modelling gene expression as a way to learn molecular genetics and diseases with a genetic component. The study is framed in Tiberghien's (2000) two worlds of knowledge, the world of "theories & models" and the world of "objects & events", adding a third component, the world of representations. We seek to examine how modelling and argumentation interact and connect the three worlds of knowledge while modelling gene expression. It is a case study of 10th graders learning about diseases with a genetic component. The research questions are as follows: (1) What argumentative and modelling operations do students enact in the process of modelling gene expression? Specifically, which operations allow connecting the three worlds of knowledge? (2) What are the interactions between modelling and argumentation in modelling gene expression? To what extent do these interactions help students connect the three worlds of knowledge and modelling gene expression? The argumentative operation of using evidence helps students to relate the three worlds of knowledge, enacted in all the connections. It seems to be a relationship among the number of interactions between modelling and argumentation, the connections between world of knowledge and students' capacity to develop a more sophisticated representation. Despite this is a case study, this approach of analysis reveals potentialities for a deeper understanding of learning genetics though scientific practices.

  13. Operant conditioning of facial displays of pain.

    Science.gov (United States)

    Kunz, Miriam; Rainville, Pierre; Lautenbacher, Stefan

    2011-06-01

    The operant model of chronic pain posits that nonverbal pain behavior, such as facial expressions, is sensitive to reinforcement, but experimental evidence supporting this assumption is sparse. The aim of the present study was to investigate in a healthy population a) whether facial pain behavior can indeed be operantly conditioned using a discriminative reinforcement schedule to increase and decrease facial pain behavior and b) to what extent these changes affect pain experience indexed by self-ratings. In the experimental group (n = 29), the participants were reinforced every time that they showed pain-indicative facial behavior (up-conditioning) or a neutral expression (down-conditioning) in response to painful heat stimulation. Once facial pain behavior was successfully up- or down-conditioned, respectively (which occurred in 72% of participants), facial pain displays and self-report ratings were assessed. In addition, a control group (n = 11) was used that was yoked to the reinforcement plans of the experimental group. During the conditioning phases, reinforcement led to significant changes in facial pain behavior in the majority of the experimental group (p .136). Fine-grained analyses of facial muscle movements revealed a similar picture. Furthermore, the decline in facial pain displays (as observed during down-conditioning) strongly predicted changes in pain ratings (R(2) = 0.329). These results suggest that a) facial pain displays are sensitive to reinforcement and b) that changes in facial pain displays can affect self-report ratings.

  14. Caspase-dependent inhibition of store-operated Ca2+ entry into apoptosis-committed Jurkat cells

    International Nuclear Information System (INIS)

    Onopiuk, Marta; Wierzbicka, Katarzyna; Brutkowski, Wojciech; Szczepanowska, Joanna; Zablocki, Krzysztof

    2010-01-01

    Activation of T-cells triggers store-operated Ca 2+ entry, which begins a signaling cascade leading to induction of appropriate gene expression and eventually lymphocyte proliferation and differentiation. The simultaneous enhancement of Fas ligand gene expression in activated cells allows the immune response to be limited by committing the activated cells to apoptosis. In apoptotic cells the store-operated calcium entry is significantly inhibited. It has been documented that moderate activation of Fas receptor may cause reversible inhibition of store-operated channels by ceramide released from hydrolyzed sphingomyelin. Here we show that activation of Fas receptor in T-cells results in caspase-dependent decrease of cellular STIM1 and Orai1 protein content. This effect may be responsible for the substantial inhibition of Ca 2+ entry into Jurkat cells undergoing apoptosis. In turn, this inhibition might prevent overloading of cells with calcium and protect them against necrosis. -- Research highlights: → Fas activation reduces STIM1 and Orai1 protein content in caspase dependent manner. → Fas activation partially reduces mitochondrial potential in caspase dependent manner. → Fas stimulation inhibits of store-operated Ca 2+ entry in caspase dependent manner. → Inhibition of Ca 2+ entry in apoptotic cells may protect them from secondary necrosis.

  15. An Abstract Coalgebraic Approach to Process Equivalence for Well- Behaved Operational Semantics

    DEFF Research Database (Denmark)

    Klin, Bartek

    This thesis is part of the programme aimed at finding a mathematical theory of well-behaved structural operational semantics. General and basic results shown in 1997 in a seminal paper by Turi and Plotkin are extended in two directions, aiming at greater expressivity of the framework. The so-call...

  16. Guiding rational reservoir flood operation using penalty-type genetic algorithm

    Science.gov (United States)

    Chang, Li-Chiu

    2008-06-01

    SummaryReal-time flood control of a multi-purpose reservoir should consider decreasing the flood peak stage downstream and storing floodwaters for future usage during typhoon seasons. This study proposes a reservoir flood control optimization model with linguistic description of requirements and existing regulations for rational operating decisions. The approach involves formulating reservoir flood operation as an optimization problem and using the genetic algorithm (GA) as a search engine. The optimizing formulation is expressed not only by mathematical forms of objective function and constraints, but also by no analytic expression in terms of parameters. GA is used to search a global optimum of a mixture of mathematical and nonmathematical formulations. Due to the great number of constraints and flood control requirements, it is difficult to reach a solution without violating constraints. To tackle this bottleneck, the proper penalty strategy for each parameter is proposed to guide the GA searching process. The proposed approach is applied to the Shihmen reservoir in North Taiwan for finding the rational release and desired storage as a case study. The hourly historical data sets of 29 typhoon events that have hit the area in last thirty years are investigated bye the proposed method. To demonstrate the effectiveness of the proposed approach, the simplex method was performed. The results demonstrated that a penalty-type genetic algorithm could effectively provide rational hydrographs to reduce flood damage during the flood operation and to increase final storage for future usages.

  17. Message Correlation for Conversation Reconstruction in Service Interaction Logs

    OpenAIRE

    Motahari Nezhad, Hamid R.; Saint-Paul, Regis; Benatallah, Boualem; Casati, Fabio; Andritsos, Periklis

    2007-01-01

    The problem of understanding the behavior of business processes and of services is rapidly becoming a priority in medium and large companies. To this end, recently, analysis tools as well as variations of data mining techniques have been applied to process and service execution logs to perform OLAP-style analysis and to discover behavioral (process and protocol) models out of execution data. All these approaches are based on one key assumption: events describing executions and stored in proce...

  18. Ulam method and fractal Weyl law for Perron-Frobenius operators

    Science.gov (United States)

    Ermann, L.; Shepelyansky, D. L.

    2010-06-01

    We use the Ulam method to study spectral properties of the Perron-Frobenius operators of dynamical maps in a chaotic regime. For maps with absorption we show numerically that the spectrum is characterized by the fractal Weyl law recently established for nonunitary operators describing poles of quantum chaotic scattering with the Weyl exponent ν = d-1, where d is the fractal dimension of corresponding strange set of trajectories nonescaping in future times. In contrast, for dissipative maps we numerically find the Weyl exponent ν = d/2 where d is the fractal dimension of strange attractor. The Weyl exponent can be also expressed via the relation ν = d0/2 where d0 is the fractal dimension of the invariant sets. We also discuss the properties of eigenvalues and eigenvectors of such operators characterized by the fractal Weyl law.

  19. Facial expressions recognition with an emotion expressive robotic head

    Science.gov (United States)

    Doroftei, I.; Adascalitei, F.; Lefeber, D.; Vanderborght, B.; Doroftei, I. A.

    2016-08-01

    The purpose of this study is to present the preliminary steps in facial expressions recognition with a new version of an expressive social robotic head. So, in a first phase, our main goal was to reach a minimum level of emotional expressiveness in order to obtain nonverbal communication between the robot and human by building six basic facial expressions. To evaluate the facial expressions, the robot was used in some preliminary user studies, among children and adults.

  20. The anomalous dimension of the gluon-ghost mass operator in Yang-Mills theory

    International Nuclear Information System (INIS)

    Dudal, D.; Verschelde, H.; Lemes, V.E.R.; Sarandy, M.S.; Sobreiro, R.; Sorella, S.P.; Picariello, M.; Gracey, J.A.

    2003-01-01

    The local composite gluon-ghost operator (((1)/(2))A aμ A μ a +αc-bar a c a ) is analysed in the framework of the algebraic renormalization in SU(N) Yang-Mills theories in the Landau, Curci-Ferrari and maximal abelian gauges. We show, to all orders of perturbation theory, that this operator is multiplicatively renormalizable. Furthermore, its anomalous dimension is not an independent parameter of the theory, being given by a general expression valid in all these gauges. We also verify the relations we obtain for the operator anomalous dimensions by explicit 3-loop calculations in the MS-bar scheme for the Curci-Ferrari gauge

  1. Facial expression judgments support a socio-relational model, rather than a negativity bias model of political psychology.

    Science.gov (United States)

    Vigil, Jacob M; Strenth, Chance

    2014-06-01

    Self-reported opinions and judgments may be more rooted in expressive biases than in cognitive processing biases, and ultimately operate within a broader behavioral style for advertising the capacity - versus the trustworthiness - dimension of human reciprocity potential. Our analyses of facial expression judgments of likely voters are consistent with this thesis, and directly contradict one major prediction from the authors' "negativity-bias" model.

  2. Collaboration and Evolution of E-Commerce and Express Delivery Industry Supply Chain

    Directory of Open Access Journals (Sweden)

    Ying Xu

    2016-01-01

    Full Text Available Considering the contradictions between the electronic commerce (e-commerce and its matching express delivery service, this paper investigates a supply chain regarding e-commerce and express delivery industry, in which collaborative operations of enterprises are discussed. The profitability and collaboration capability acting as order parameters and the rest of the influential resources including logistics, fund, information, and commodity are selected with their interrelations being examined based on servo theory of synergetics. Besides, evolutionary model of the e-commerce and express delivery industry is established and analyzed according to self-organization method of system dynamic theory to illustrate order parameters’ role in system evolution, and numerical analyses emerged to intuitively demonstrate the solutions. We conclude the work along with its results of significant references for investigating resource integrations by combining the two closely related businesses in an entire cooperative supply chain and providing guidelines for e-commerce and express delivery enterprises and industries in effective collaboration and system evolution.

  3. Basic properties of the current-current correlation measure for random Schroedinger operators

    International Nuclear Information System (INIS)

    Hislop, Peter D.; Lenoble, Olivier

    2006-01-01

    The current-current correlation measure plays a crucial role in the theory of conductivity for disordered systems. We prove a Pastur-Shubin-type formula for the current-current correlation measure expressing it as a thermodynamic limit for random Schroedinger operators on the lattice and the continuum. We prove that the limit is independent of the self-adjoint boundary conditions and independent of a large family of expanding regions. We relate this finite-volume definition to the definition obtained by using the infinite-volume operators and the trace-per-unit volume

  4. NM23 protein expression in colorectal carcinoma using TMA (tissue microarray: association with metastases and survival

    Directory of Open Access Journals (Sweden)

    Levindo Alves de Oliveira

    2010-12-01

    Full Text Available CONTEXT: NM23, a metastasis suppressor gene, may be associated with prognosis in patients with colorectal carcinoma. OBJECTIVE: To analyze NM23 expression and its association with the presence of lymph node and liver metastases and survival in patients operated on for colorectal carcinoma. METHODS: One hundred thirty patients operated on for colorectal carcinoma were investigated. Tissue microarray blocks containing neoplastic tissue and tumor-adjacent non-neoplastic mucosa were obtained and analyzed by immunohistochemical staining using a monoclonal anti-NM23 antibody. Immunohistochemical expression was assessed using a semiquantitative scoring method, counting the percentage of stained cells. The results were compared regarding morphological and histological characteristics of the colorectal carcinoma, presence of lymph node and liver metastases, tumor staging, and patient survival. Statistical analysis was performed using the Mann-Whitney test, the Kruskal-Wallis test and Fisher's exact test. Survival analysis was performed using the Kaplan-Meier method and the log-rank test. RESULTS: NM23 expression was higher in colorectal carcinoma tissue than in adjacent non-neoplastic mucosa (P<0.0001. NM23 protein expression did not correlate with degree of cell differentiation (P = 0.57, vascular invasion (P = 0.85, lymphatic invasion (P = 0.41, perineural infiltration (P = 0.46, staging (P = 0.19, lymph node metastases (P = 0.08, or liver metastases (P = 0.59. Disease-free survival showed significant association (P = 0.01 with the intensity of NM23 protein immunohistochemical expression in colorectal carcinoma tissue, whereas overall survival showed no association with NM23 protein expression (P = 0.13. CONCLUSIONS: NM23 protein expression was higher in neoplastic colorectal carcinoma tissue than in adjacent non-neoplastic mucosa, showing no correlation with morphological aspects, presence of lymph node or liver metastases, colorectal carcinoma

  5. EXPRESSION OF THE TRANSPORT SECTOR OPERATIONAL EFFICIENCY EVALUATION METHODOLOGY (TRENDS AT DIFFERENT STAGES OF THE ECONOMIC CYCLE

    Directory of Open Access Journals (Sweden)

    Deimena KIYAK

    2017-12-01

    Full Text Available It is important to evaluate the impact of economic fluctuations on the transport sector operational efficiency, since such an analysis is a source of economic information which contributes to the identification of the sector's potential and advantages, the establishment of the risky areas of activity, and the exploration of the opportunities to increase its effectiveness. The aim of the study was to apply mathematical evaluation methods to the exploration of the operational efficiency of the Lithuanian transport sector companies and, based on the outcomes, to validate the opportunity of predicting a potential change of the economic cycle. The operational efficiency of the Lithuanian transport sector was analysed in the context of the cyclical national economy, and not in individual economic boom or recession periods, as that allowed for more detailed evaluation of the specific activities of the sector and its impact on Lithuanian economy. To achieve the aim, three different stages of the economic cycle in Lithuania were identified, and calculations were made during them. Based on the aggregate financial data, four different economic efficiency indicators were developed that reflected the efficiency level of the entire transport sector, and the sensitivity of the transport sector to economic fluctuations was identified. The comparison of the changes in the transport sector and in Lithuanian economy made it obvious that the level of the sector's operational efficiency could be regarded as a leading indicator of the economic cycle.

  6. The role of operator ordering in quantum field theory

    International Nuclear Information System (INIS)

    Suzuki, Tsuneo; Hirshfeld, A.C.; Leschke, H.

    1980-01-01

    We study the role of operator ordering in quantum field theory. Operator ordering techniques discussed in our previous papers in the quantum mechanical context are extended to field theory. In this case formally infinite terms appear which must be given a meaning in the framework of some definite regularization scheme. Different orderings for the non-commuting operators in the interaction Hamiltonian lead in general to different expressions for the Dyson-Wick expansion of the S-matrix, implying different Feynman rules. Different orderings correspond to different assignments for the initially undetermined values of the contractions occurring in closed-loop diagrams. Combining a special class of ordering schemes (u-ordering, a generalization of Weyl-ordering) with dimensional regularization leads to important simplifications, and in this case manipulations in which ordering complications are neglected may be justified. We use our methods to discuss gauge invariance in scalar electrodynamics, and the equivalent theorem for a reducible field theoretical model. (author)

  7. STIM and Orai isoform expression in pregnant human myometrium: a potential role in calcium signaling during pregnancy.

    Directory of Open Access Journals (Sweden)

    Evonne eChin-Smith

    2014-05-01

    Full Text Available Store-operated calcium (Ca2+ entry (SOCE can be mediated by two novel proteins, STIM/Orai. We have previously demonstrated that members of the TRPC family, putative basal and store operated calcium entry channels, are present in human myometrium and regulated by labor associated stimuli IL-1β and mechanical stretch. Although STIM and Orai isoforms (1-3 have been reported in other smooth muscle cell types, there is little known about the expression or gestational regulation of STIM and Orai expression in human myometrium. Total RNA was isolated from lower segment human myometrial biopsies obtained at caesarean section from women at the time of preterm no labor (PTNL, preterm labor (PTL, term non-labor (TNL and term with labor (TL; primary cultured human uterine smooth muscle cells, and a human myometrial cell line (hTERT-HM. STIM1-2, and Orai1-3 mRNA expression was assessed by quantitative real-time PCR. All five genes were expressed in myometrial tissue and cultured cells. Orai2 was the most abundant Orai isoform in human myometrium. Expression of STIM1-2/Orai1-3 did not alter with the onset of labor. Orai1 mRNA expression in cultured cells was enhanced by IL-1β treatment. This novel report of STIM1-2 and Orai1-3 mRNA expression in pregnant human myometrium and Orai1 regulation by IL-1β indicates a potential role for these proteins in calcium signaling in human myometrium during pregnancy.

  8. On strong-coupling correlation functions of circular Wilson loops and local operators

    International Nuclear Information System (INIS)

    Alday, Luis F; Tseytlin, Arkady A

    2011-01-01

    Motivated by the problem of understanding 3-point correlation functions of gauge-invariant operators in N=4 super Yang-Mills theory we consider correlators involving Wilson loops and a 'light' operator with fixed quantum numbers. At leading order in the strong-coupling expansion such correlators are given by the 'light' vertex operator evaluated on a semiclassical string world surface ending on the corresponding loops at the boundary of AdS 5 x S 5 . We study in detail the example of a correlator of two concentric circular Wilson loops and a dilaton vertex operator. The resulting expression is given by an integral of combinations of elliptic functions and can be computed analytically in some special limits. We also consider a generalization of the minimal surface ending on two circles to the case of non-zero angular momentum J in S 5 and discuss a special limit when one of the Wilson loops is effectively replaced by a 'heavy' operator with charge J. (paper)

  9. Introduction of the information system research and development department at Kansai Electric Power Company. Company uses the latest information processing technology to respond to customers' needs to structure an information system; Kanden joho system no kenkyu kaihatsu bumon no shokai. Saishin no joho shori gijutsu ni yori, okyakusama no joho system ka no needs ni okotaeshimasu

    Energy Technology Data Exchange (ETDEWEB)

    Ashida, Y. [Kansai Electric Power Co. Inc., Osaka (Japan)

    1998-12-10

    This paper introduces the research and development on the information processing technology at the Kansai Electric Power Company. In the research of a system development technology utilizing the object orientation, works are being made on the Java language drawing attention as an intranet development environment and the common object request broker architecture (CORBA). In the research of a technology to operate and control a large-scale network, basing on the current status of the KIND net of the Kansai Electric Power Company, discussions are being given on expanding and improving the functions of system tools made by Hitachi, Ltd. with an intention of achieving unified operation and control of the networks including not only the CSS system, but the host system. In the investigations and researches on different kinds of tools intended for data warehouse structuring, products are investigated and methods are discussed, such as the data extracting and editing tools to structure databases, and the on-line analysis processing (OLAP) tool to retrieve and analyze a great quantity of data. Researches are being made on application of the visual private office (VPO) service on the Internet, and on applicability evaluation for the individual certification technology. Investigations are being made on applicability of the enterprise resource planning (ERP) package. (NEDO)

  10. Results of investigation of the functional state of operators involved in 8- and 12-hour shift rotations

    International Nuclear Information System (INIS)

    Chernyuk, V.I.; Zakharenko, M.I.; Nosovskij, A.V.; Lastovchenko, V.B.; Petrichenko, A.A.; Panchenko, V.I.; Lipovoj, V.V.; Pugach, A.B.

    1996-01-01

    The functional state of operators of block and central control panels of the Chernobyl NPP involved in 8- and 12-hour shift rotations was studied. Basing of the results of changes in indices of the subjective state, activation of the central nervous system, arterial pressure, heart rate, body temperature it was established that day shifts were characterized by higher functional tension whereas night shifts by mote expressed fatigue. The work with the 8-hour rotation schedule in comparison with 12-hour one appeared to be less favourable for the functional state of operators because it resulted in over excitation of the central nervous system and was characterized by more expressed fatigue in night shifts

  11. A knowledge-Induced Operator Model

    Directory of Open Access Journals (Sweden)

    M.A. Choudhury

    2007-06-01

    Full Text Available Learning systems are in the forefront of analytical investigation in the sciences. In the social sciences they occupy the study of complexity and strongly interactive world-systems. Sometimes they are diversely referred to as symbiotics and semiotics when studied in conjunction with logical expressions. In the mathematical sciences the methodology underlying learning systems with complex behavior is based on formal logic or systems analysis. In this paper relationally learning systems are shown to transcend the space-time domain of scientific investigation into the knowledge dimension. Such a knowledge domain is explained by pervasive interaction leading to integration and followed by continuous evolution as complementary processes existing between entities and systemic domains in world-systems, thus the abbreviation IIE-processes. This paper establishes a mathematical characterization of the properties of knowledge-induced process-based world-systems in the light of the epistemology of unity of knowledge signified in this paper by extensive complementarities caused by the epistemic and ontological foundation of the text of unity of knowledge, the prime example of which is the realm of the divine laws. The result is formalism in mathematical generalization of the learning phenomenon by means of an operator. This operator summarizes the properties of interaction, integration and evolution (IIE in the continuum domain of knowledge formation signified by universal complementarities across entities, systems and sub-systems in unifying world-systems. The opposite case of ‘de-knowledge’ and its operator is also briefly formalized.

  12. Facile promoter deletion in Escherichia coli in response to leaky expression of very robust and benign proteins from common expression vectors

    Directory of Open Access Journals (Sweden)

    Kawe Martin

    2009-01-01

    Full Text Available Abstract Background Overexpression of proteins in Escherichia coli is considered routine today, at least when the protein is soluble and not otherwise toxic for the host. We report here that the massive overproduction of even such "benign" proteins can cause surprisingly efficient promoter deletions in the expression plasmid, leading to the growth of only non-producers, when expression is not well repressed in the newly transformed bacterial cell. Because deletion is so facile, it might impact on high-throughput protein production, e.g. for structural genomics, where not every expression parameter will be monitored. Results We studied the high-level expression of several robust non-toxic proteins using a T5 promoter under lac operator control. Full induction leads to no significant growth retardation. We compared expression from almost identical plasmids with or without the lacI gene together in strains expressing different levels of LacI. Any combination without net overexpression of LacI led to an efficient promoter deletion in the plasmid, although the number of growing colonies and even the plasmid size – all antibiotic-resistant non-producers – was almost normal, and thus the problem not immediately recognizable. However, by assuring sufficient repression during the initial establishment phase of the plasmid, deletion was completely prevented. Conclusion The deletions in the insufficiently repressed system are caused entirely by the burden of high-level translation. Since the E. coli Dps protein, known to protect DNA against stress in the stationary phase, is accumulated in the deletion mutants, the mutation may have taken place during a transient stationary phase. The cause of the deletion is thus distinct from the well known interference of high-level transcription with plasmid replication. The deletion can be entirely prevented by overexpressing LacI, a useful precaution even without any signs of stress caused by the protein.

  13. Mining gene expression data of multiple sclerosis.

    Directory of Open Access Journals (Sweden)

    Pi Guo

    Full Text Available Microarray produces a large amount of gene expression data, containing various biological implications. The challenge is to detect a panel of discriminative genes associated with disease. This study proposed a robust classification model for gene selection using gene expression data, and performed an analysis to identify disease-related genes using multiple sclerosis as an example.Gene expression profiles based on the transcriptome of peripheral blood mononuclear cells from a total of 44 samples from 26 multiple sclerosis patients and 18 individuals with other neurological diseases (control were analyzed. Feature selection algorithms including Support Vector Machine based on Recursive Feature Elimination, Receiver Operating Characteristic Curve, and Boruta algorithms were jointly performed to select candidate genes associating with multiple sclerosis. Multiple classification models categorized samples into two different groups based on the identified genes. Models' performance was evaluated using cross-validation methods, and an optimal classifier for gene selection was determined.An overlapping feature set was identified consisting of 8 genes that were differentially expressed between the two phenotype groups. The genes were significantly associated with the pathways of apoptosis and cytokine-cytokine receptor interaction. TNFSF10 was significantly associated with multiple sclerosis. A Support Vector Machine model was established based on the featured genes and gave a practical accuracy of ∼86%. This binary classification model also outperformed the other models in terms of Sensitivity, Specificity and F1 score.The combined analytical framework integrating feature ranking algorithms and Support Vector Machine model could be used for selecting genes for other diseases.

  14. Decreased expression of fibulin-4 in aortic wall of aortic dissection.

    Science.gov (United States)

    Huawei, P; Qian, C; Chuan, T; Lei, L; Laing, W; Wenlong, X; Wenzhi, L

    2014-02-01

    In this research, we will examine the expression of Fibulin-4 in aortic wall to find out its role in aortic dissection development. The samples of aortic wall were obtained from 10 patients operated for acute ascending aortic dissection and five patients for chronic ascending aortic dissection. Another 15 pieces of samples from patients who had coronary artery bypass were as controls. The aortic samples were stained with aldehyde magenta dyeing to evaluate the arrangement of elastic fibers. The Fibulin-4 protein and mRNA expression were both determined by Western blot and realtime quantitative polymerase chain reaction. Compared with the control group, both in acute and chronic ascending aortic dissection, elastic fiber fragments increased and the expression of fibulin-4 protein significantly decreased (P= 0.045 < 0.05). The level of fibulin-4 mRNA decreased in acute ascending aortic dissection (P= 0.034 < 0.05), while it increased in chronic ascending aortic dissection (P=0.004 < 0.05). The increased amounts of elastic fiber fragments were negatively correlated with the expression of fibulin-4 mRNA in acute ascending aortic dissection. In conclusion, in aortic wall of ascending aortic dissection, the expression of fibulin-4 protein decreased and the expression of fibulin-4 mRNA was abnormal. Fibulin-4 may play an important role in the pathogenesis of aortic dissection.

  15. Extracción de esquemas relacionales para la construcción de un modelo multidimensional bajo la web

    Directory of Open Access Journals (Sweden)

    Sandra D. Orantes J.

    2004-01-01

    Full Text Available Actualmente, la tecnología de información (TI se orienta en el intercambio a sistemas de información basados en la web (SIW. En este documento se discute el avance de un SIW que permitirá la generación de consultas tipo OLAP (Online Analytical Processing, proceso analítico en línea de forma distribuida, donde el usuario podrá diseñar y generar esquemas multidimensionales a partir de fuentes de datos heterogéneas, en diversos sitios de la web, el modelo de esquemas multidimensionales es necesario para las herramientas OLAP orientadas a un DSS (Decision Support System, sistema de soporte para la toma de decisiones. Como parte inicial, se comprende el módulo de extracción de esquemas relacionales de las bases de datos, para transmitirlos a un sitio que se encargará de la integración de esquemas hacia el modelo multidimensional. Se empleará como formato de transmisión de datos el XML Schema (eXtensible Markup Language, esquema de lenguaje de marcas extensibles usando conexiones JDBC (Java Database Connectivity, conectividad java –lenguaje de programación desarrollado por Sun Microsystems en 1992- a base de datos y transformaciones XSLT (eXtensible Sytlesheet Language Transformations, lenguaje de transformaciones de hojas de estilo extensible.

  16. High Performance Analytics with the R3-Cache

    Science.gov (United States)

    Eavis, Todd; Sayeed, Ruhan

    Contemporary data warehouses now represent some of the world’s largest databases. As these systems grow in size and complexity, however, it becomes increasingly difficult for brute force query processing approaches to meet the performance demands of end users. Certainly, improved indexing and more selective view materialization are helpful in this regard. Nevertheless, with warehouses moving into the multi-terabyte range, it is clear that the minimization of external memory accesses must be a primary performance objective. In this paper, we describe the R 3-cache, a natively multi-dimensional caching framework designed specifically to support sophisticated warehouse/OLAP environments. R 3-cache is based upon an in-memory version of the R-tree that has been extended to support buffer pages rather than disk blocks. A key strength of the R 3-cache is that it is able to utilize multi-dimensional fragments of previous query results so as to significantly minimize the frequency and scale of disk accesses. Moreover, the new caching model directly accommodates the standard relational storage model and provides mechanisms for pro-active updates that exploit the existence of query “hot spots”. The current prototype has been evaluated as a component of the Sidera DBMS, a “shared nothing” parallel OLAP server designed for multi-terabyte analytics. Experimental results demonstrate significant performance improvements relative to simpler alternatives.

  17. An improved hybrid multi-criteria/multidimensional model for strategic industrial location selection: Casablanca industrial zones as a case study.

    Science.gov (United States)

    Boutkhoum, Omar; Hanine, Mohamed; Agouti, Tarik; Tikniouine, Abdessadek

    2015-01-01

    In this paper, we examine the issue of strategic industrial location selection in uncertain decision making environments for implanting new industrial corporation. In fact, the industrial location issue is typically considered as a crucial factor in business research field which is related to many calculations about natural resources, distributors, suppliers, customers, and most other things. Based on the integration of environmental, economic and social decisive elements of sustainable development, this paper presents a hybrid decision making model combining fuzzy multi-criteria analysis with analytical capabilities that OLAP systems can provide for successful and optimal industrial location selection. The proposed model mainly consists in three stages. In the first stage, a decision-making committee has been established to identify the evaluation criteria impacting the location selection process. In the second stage, we develop fuzzy AHP software based on the extent analysis method to assign the importance weights to the selected criteria, which allows us to model the linguistic vagueness, ambiguity, and incomplete knowledge. In the last stage, OLAP analysis integrated with multi-criteria analysis employs these weighted criteria as inputs to evaluate, rank and select the strategic industrial location for implanting new business corporation in the region of Casablanca, Morocco. Finally, a sensitivity analysis is performed to evaluate the impact of criteria weights and the preferences given by decision makers on the final rankings of strategic industrial locations.

  18. Data Intensive Architecture for Scalable Cyber Analytics

    Energy Technology Data Exchange (ETDEWEB)

    Olsen, Bryan K.; Johnson, John R.; Critchlow, Terence J.

    2011-12-19

    Cyber analysts are tasked with the identification and mitigation of network exploits and threats. These compromises are difficult to identify due to the characteristics of cyber communication, the volume of traffic, and the duration of possible attack. In this paper, we describe a prototype implementation designed to provide cyber analysts an environment where they can interactively explore a month’s worth of cyber security data. This prototype utilized On-Line Analytical Processing (OLAP) techniques to present a data cube to the analysts. The cube provides a summary of the data, allowing trends to be easily identified as well as the ability to easily pull up the original records comprising an event of interest. The cube was built using SQL Server Analysis Services (SSAS), with the interface to the cube provided by Tableau. This software infrastructure was supported by a novel hardware architecture comprising a Netezza TwinFin® for the underlying data warehouse and a cube server with a FusionIO drive hosting the data cube. We evaluated this environment on a month’s worth of artificial, but realistic, data using multiple queries provided by our cyber analysts. As our results indicate, OLAP technology has progressed to the point where it is in a unique position to provide novel insights to cyber analysts, as long as it is supported by an appropriate data intensive architecture.

  19. Study and application of data mining and data warehouse in CIMS

    Science.gov (United States)

    Zhou, Lijuan; Liu, Chi; Liu, Daxin

    2003-03-01

    The interest in analyzing data has grown tremendously in recent years. To analyze data, a multitude of technologies is need, namely technologies from the fields of Data Warehouse, Data Mining, On-line Analytical Processing (OLAP). This paper gives a new architecture of data warehouse in CIMS according to CRGC-CIMS application engineering. The data source of this architecture comes from database of CRGC-CIMS system. The data is put in global data set by extracting, filtrating and integrating, and then the data is translated to data warehouse according information request. We have addressed two advantages of the new model in CRGC-CIMS application. In addition, a Data Warehouse contains lots of materialized views over the data provided by the distributed heterogeneous databases for the purpose of efficiently implementing decision-support, OLAP queries or data mining. It is important to select the right view to materialize that answer a given set of queries. In this paper, we also have designed algorithms for selecting a set of views to be materialized in a data warehouse in order to answer the most queries under the constraint of given space. First, we give a cost model for selecting materialized views. Then we give the algorithms that adopt gradually recursive method from bottom to top. We give description and realization of algorithms. Finally, we discuss the advantage and shortcoming of our approach and future work.

  20. High Expression of HULC Is Associated with Poor Prognosis in Osteosarcoma Patients.

    Directory of Open Access Journals (Sweden)

    Vanessa Regina Maciel Uzan

    Full Text Available Osteosarcoma (OS is the most common primary bone cancer in childhood. OS is an aggressive disease, and metastatic patients evolve with very poor clinical outcomes. Genetically, OSs are extremely complex tumors, and the related metastatic process is not well understood in terms of the biology of the disease. In this context, long non-coding RNAs (lncRNAs have emerged as an important class of gene expression regulators that play key roles in the invasion and metastasis of several human tumors. Here, we evaluated the expression of HULC, which is an lncRNA that is associated with the tumor metastatic process, and assessed its potential role as a prognostic marker in OS. HULC expression was evaluated in primary OS samples using real-time RT-PCR. HULC expression status was determined by receiver operating characteristic (ROC analysis, and its association with survival was assessed using the Kaplan-Meier method. The HULC expression level was not significantly associated with the clinicopathological characteristics of the OS patients. However, our data demonstrated that higher levels of expression of HULC were associated with lower survival rates in OS patients, both in terms of overall and event-free survival. Elevated HULC expression was associated with poor clinical outcomes among the OS patients, which suggests that HULC could be a potential prognostic biomarker in OS.

  1. Derivation of equations for scalar and fermion fields using properties of dispersion-codispersion operators

    International Nuclear Information System (INIS)

    Raoelina Andriambololona; Ranaivoson, R.T.R; Hanitriarivo, R.; Harison, V.

    2014-01-01

    We establish equations for scalar and fermion fields using results obtained from a study on a phase space representation of quantum theory that we have performed in a previous work. Our approaches are similar to the historical ones to obtain Klein-Gordon and Dirac equations but the main difference is that ours are based on the use of properties of operators called dispersion-codispersion operators. We begin with a brief recall about the dispersion-codispersion operators. Then, introducing a mass operator with its canonical conjugate coordinate and applying rules of quantization, based on the use of dispersion - codispersion operators , we deduce a second order differential operator relation from the relativistic expression relying energy, momentum and mass. Using Dirac matrices, we derive from this second order differential operator relation a first order one. The application of the second order differential operator relation on a scalar function gives the equation for the scalar field and the use of the first order differential operator relation leads to the equation for fermion field.

  2. Cytomegalovirus replicon-based regulation of gene expression in vitro and in vivo.

    Directory of Open Access Journals (Sweden)

    Hermine Mohr

    Full Text Available There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can be used to activate or increase the expression of adjacent genes. Cell lines carrying an episomal vector, in which reporter genes are linked to the murine cytomegalovirus (MCMV origin of lytic replication (oriLyt, were constructed. Reporter gene expression was silenced by a histone-deacetylase-dependent mechanism, but was resolved upon lytic infection with MCMV. Replication of the episome was observed subsequent to infection, leading to the induction of gene expression by more than 1000-fold. oriLyt-based regulation thus provided a unique opportunity for virus-induced conditional gene expression without the need for an additional induction mechanism. This principle was exploited to show effective late trans-complementation of the toxic viral protein M50 and the glycoprotein gO of MCMV. Moreover, the application of this principle for intracellular immunization against herpesvirus infection was demonstrated. The results of the present study show that viral infection specifically activated the expression of a dominant-negative transgene, which inhibited viral growth. This conditional system was operative in explant cultures of transgenic mice, but not in vivo. Several applications are discussed.

  3. Your Lung Operation: After Your Operation

    Medline Plus

    Full Text Available ... Lung Operation After Your Operation Your Discharge and Recovery Complete Video After Your Operation Guidance for after ... Your Lung Operation Read Next Your Discharge and Recovery Back to Top Find A Surgeon Find A ...

  4. Self-energy operator for an electron in an external Coulomb potential. II

    International Nuclear Information System (INIS)

    Hostler, L.

    1988-01-01

    Relativistic Coulomb Sturmian matrix elements of the operator Oequivalentln(1-rho)/rho, rho = -[πx(1+iσ)xπ]/m 2 , in terms of which the self-energy operator for an electron in an external Coulomb potential has been expressed, are studied. The operator O is dealt with on a term by term basis in a Sturmian expansion. Each term of the Sturmian expansion is separated into a part whose matrix elements are analytic functions of Zα, plus a remainder evaluated in closed form by use of the Cauchy residue theorem. All ignorance about the matrix element of the general term in the Sturmian expansion of O is thereby placed entirely in the analytic part, for which an explicit integral representation is derived

  5. Scalar and configuration traces of operators in large spectroscopic spaces

    International Nuclear Information System (INIS)

    Chang, B.D.; Wong, S.S.M.

    1978-01-01

    In statistical spectroscopic calculations, the primary input is the trace of products of powers of Hamiltonian and excitation operators. The lack of a systematic approach to trace evaluation has been in the past one of the major difficulties in the applications of statistical spectroscopic methods. A general method with a simple derivation is described here to evaluate the scalar and configuration traces for operators expressed either in the m-scheme or fully coupled JT scheme. It is shown to be an effective method by actually programming it on a computer. Implications on the future applications of statistical spectroscopy in the area of level density, strength function and perturbation theory are also briefly discussed. (Auth.)

  6. Mapping photothermally induced gene expression in living cells and tissues by nanorod-locked nucleic acid complexes.

    Science.gov (United States)

    Riahi, Reza; Wang, Shue; Long, Min; Li, Na; Chiou, Pei-Yu; Zhang, Donna D; Wong, Pak Kin

    2014-04-22

    The photothermal effect of plasmonic nanostructures has numerous applications, such as cancer therapy, photonic gene circuit, large cargo delivery, and nanostructure-enhanced laser tweezers. The photothermal operation can also induce unwanted physical and biochemical effects, which potentially alter the cell behaviors. However, there is a lack of techniques for characterizing the dynamic cell responses near the site of photothermal operation with high spatiotemporal resolution. In this work, we show that the incorporation of locked nucleic acid probes with gold nanorods allows photothermal manipulation and real-time monitoring of gene expression near the area of irradiation in living cells and animal tissues. The multimodal gold nanorod serves as an endocytic delivery reagent to transport the probes into the cells, a fluorescence quencher and a binding competitor to detect intracellular mRNA, and a plasmonic photothermal transducer to induce cell ablation. We demonstrate the ability of the gold nanorod-locked nucleic acid complex for detecting the spatiotemporal gene expression in viable cells and tissues and inducing photothermal ablation of single cells. Using the gold nanorod-locked nucleic acid complex, we systematically characterize the dynamic cellular heat shock responses near the site of photothermal operation. The gold nanorod-locked nucleic acid complex enables mapping of intracellular gene expressions and analyzes the photothermal effects of nanostructures toward various biomedical applications.

  7. Expression of SET Protein in the Ovaries of Patients with Polycystic Ovary Syndrome.

    Science.gov (United States)

    Boqun, Xu; Xiaonan, Dai; Yugui, Cui; Lingling, Gao; Xue, Dai; Gao, Chao; Feiyang, Diao; Jiayin, Liu; Gao, Li; Li, Mei; Zhang, Yuan; Ma, Xiang

    2013-01-01

    Background. We previously found that expression of SET gene was up-regulated in polycystic ovaries by using microarray. It suggested that SET may be an attractive candidate regulator involved in the pathophysiology of polycystic ovary syndrome (PCOS). In this study, expression and cellular localization of SET protein were investigated in human polycystic and normal ovaries. Method. Ovarian tissues, six normal ovaries and six polycystic ovaries, were collected during transsexual operation and surgical treatment with the signed consent form. The cellular localization of SET protein was observed by immunohistochemistry. The expression levels of SET protein were analyzed by Western Blot. Result. SET protein was expressed predominantly in the theca cells and oocytes of human ovarian follicles in both PCOS ovarian tissues and normal ovarian tissues. The level of SET protein expression in polycystic ovaries was triple higher than that in normal ovaries (P polycystic ovaries more than that in normal ovaries. Combined with its localization in theca cells, SET may participate in regulating ovarian androgen biosynthesis and the pathophysiology of hyperandrogenism in PCOS.

  8. Efficacy of Bevacizumab combined with EX-PRESS in the treatment of refractory glaucoma

    Directory of Open Access Journals (Sweden)

    Qian Wang

    2018-03-01

    Full Text Available AIM:To investigate the efficacy of Bevacizumab intravitreal injection combined with EX-PRESS in the treatment of refractory glaucoma. METHODS: The research objects were 150 cases(150 eyesof patients with refractory glaucoma from June 2014 to December 2016 in our hospital. All patients were treated with EX-PRESS glaucoma drainage device implantation, and their medicine data were analyzed retrospectively. Totally 70 cases(70 eyeswere treated with EX-PRESS only were set as the control group; 80 cases(80 eyesreceived bevacizumab intravitreal injection on the basis of the treatment of the control group were set as the observation group. The successful rate of operation was evaluated, the intraocular pressure was measured before operation and at 7d, 1, 3, 6mo after treatment by non-contact conometer, followed by record of the visual acuity and complications before and after 6mo of treatment. RESULTS: The observation group's total surgical success rate was 72.5%, which was sharply higher than that of the control group(58.6%; while the partial success rate was 17.5%, which was significantly lower than that of the control group(30.0%, with statistical significance(χ2=5.453, P=0.028; χ2=4.213, P=0.047. Two groups' surgical failure rate had no distinct difference(χ2=0.000, P=1.000. There was no significant difference in visual acuity of the two groups before and after operation(P>0.05. There was no significant difference in intraocular pressure between the two groups(Fgroups=982.27, PFtime=941.88, PPP>0.05. The observation group's low intraocular pressure, anterior chamber bleeding and shallow anterior chamber incidence were significantly lower than those of the control group, there was statistical meaning(PCONCLUSION: Intravitreal injection of bevacizumab combined with EX-PRESS in the treatment of refractory glaucoma can improve the complete success rate, as well as perform effective control on complications such as short-term intraocular pressure

  9. Is this happiness I see? Biases in the identification of emotional facial expressions in depression and social phobia.

    Science.gov (United States)

    Joormann, Jutta; Gotlib, Ian H

    2006-11-01

    The present study was designed to examine the operation of depression-specific biases in the identification or labeling of facial expression of emotions. Participants diagnosed with major depression and social phobia and control participants were presented with faces that expressed increasing degrees of emotional intensity, slowly changing from a neutral to a full-intensity happy, sad, or angry expression. The authors assessed individual differences in the intensity of facial expression of emotion that was required for the participants to accurately identify the emotion being expressed. The depressed participants required significantly greater intensity of emotion than did the social phobic and the control participants to correctly identify happy expressions and less intensity to identify sad than angry expressions. In contrast, social phobic participants needed less intensity to correctly identify the angry expressions than did the depressed and control participants and less intensity to identify angry than sad expressions. Implications of these results for interpersonal functioning in depression and social phobia are discussed. (c) 2006 APA, all rights reserved.

  10. Are we training operators upside down?

    International Nuclear Information System (INIS)

    Wachtel, J.A.

    1991-01-01

    This paper addresses questions of simulator fidelity and use in the training environment of the 1990s and beyond. It reflects the basic truism that fidelity is not an end in itself, but rather a means to the end of training effectiveness. The author expresses his belief that fidelity requirements for simulators primarily used for training are different than those for simulators used primarily for engineering design, testing or research, and he questions whether the industry has lost sight of this distinction. Simulator specifications and use in the US are compared with those in other countries which have significant commercial nuclear power industries, and the differences in approach are examined. The author questions whether the requirement for simulator certification in this country, based as it is in the licensing examination process, has led to an overdependence on these machines in the training arena - for which they are not necessarily the most effective tools. The paper addresses the future usage of simulators, as the industry begins to pay increased attention to accident management. It takes a look at the changing role of the operator in the increasingly computerized control room environment in which conventional displays and controls are replaced with integrated digital systems, where operating procedures are computerized, and where the operator's function shifts from that of today's active controller to one of systems monitor and supervisor; and it poses questions about the, perhaps unreasonable demands that may be placed on plant referenced simulators to support training in operating environments quite different from those in common use today. In short, this paper asks whether the commercial nuclear power industry in the US needs to reexamine the approach to simulation, simulator fidelity, operator training and examination as the concerns of the industry shift into new directions

  11. Discrimination of gender using facial image with expression change

    Science.gov (United States)

    Kuniyada, Jun; Fukuda, Takahiro; Terada, Kenji

    2005-12-01

    By carrying out marketing research, the managers of large-sized department stores or small convenience stores obtain the information such as ratio of men and women of visitors and an age group, and improve their management plan. However, these works are carried out in the manual operations, and it becomes a big burden to small stores. In this paper, the authors propose a method of men and women discrimination by extracting difference of the facial expression change from color facial images. Now, there are a lot of methods of the automatic recognition of the individual using a motion facial image or a still facial image in the field of image processing. However, it is very difficult to discriminate gender under the influence of the hairstyle and clothes, etc. Therefore, we propose the method which is not affected by personality such as size and position of facial parts by paying attention to a change of an expression. In this method, it is necessary to obtain two facial images with an expression and an expressionless. First, a region of facial surface and the regions of facial parts such as eyes, nose, and mouth are extracted in the facial image with color information of hue and saturation in HSV color system and emphasized edge information. Next, the features are extracted by calculating the rate of the change of each facial part generated by an expression change. In the last step, the values of those features are compared between the input data and the database, and the gender is discriminated. In this paper, it experimented for the laughing expression and smile expression, and good results were provided for discriminating gender.

  12. Development and prospects of guidance system for operators in nuclear power station

    International Nuclear Information System (INIS)

    Aeba, Youichi

    1988-01-01

    In nuclear power plants, the information on plant process and the status of machinery and equipment is collected in a central control room, and operators watch the information and carry out the necessary operation according to circumstances, in this way, the stable safe operation is carried out. Recently, process parameters and the status of machinery and equipment are displayed, being classified by the objectives of monitoring, and when operators evaluate the condition of a plant, the burden of collecting required information is reduced, and the identification of the cause of abnormality and the forecast of the range of spread and the development of abnormality are eased. However, the burden of operators in the case of coping with the abnormal event in a plant is still heavy. In this report, the prospect of the operation-supporting system to which knowledge engineering is applied and the status of its development are described. The concept, system constitution, knowledge expression and inference control mechanism of the operation-supporting system, the test of the system and the results, and the perspective of the system hereafter are reported. (Kako, I.)

  13. Temporal dynamics and transcriptional control using single-cell gene expression analysis.

    Science.gov (United States)

    Kouno, Tsukasa; de Hoon, Michiel; Mar, Jessica C; Tomaru, Yasuhiro; Kawano, Mitsuoki; Carninci, Piero; Suzuki, Harukazu; Hayashizaki, Yoshihide; Shin, Jay W

    2013-01-01

    Changes in environmental conditions lead to expression variation that manifest at the level of gene regulatory networks. Despite a strong understanding of the role noise plays in synthetic biological systems, it remains unclear how propagation of expression heterogeneity in an endogenous regulatory network is distributed and utilized by cells transitioning through a key developmental event. Here we investigate the temporal dynamics of a single-cell transcriptional network of 45 transcription factors in THP-1 human myeloid monocytic leukemia cells undergoing differentiation to macrophages. We systematically measure temporal regulation of expression and variation by profiling 120 single cells at eight distinct time points, and infer highly controlled regulatory modules through which signaling operates with stochastic effects. This reveals dynamic and specific rewiring as a cellular strategy for differentiation. The integration of both positive and negative co-expression networks further identifies the proto-oncogene MYB as a network hinge to modulate both the pro- and anti-differentiation pathways. Compared to averaged cell populations, temporal single-cell expression profiling provides a much more powerful technique to probe for mechanistic insights underlying cellular differentiation. We believe that our approach will form the basis of novel strategies to study the regulation of transcription at a single-cell level.

  14. Dissociation between facial and bodily expressions in emotion recognition: A case study.

    Science.gov (United States)

    Leiva, Samanta; Margulis, Laura; Micciulli, Andrea; Ferreres, Aldo

    2017-12-21

    Existing single-case studies have reported deficit in recognizing basic emotions through facial expression and unaffected performance with body expressions, but not the opposite pattern. The aim of this paper is to present a case study with impaired emotion recognition through body expressions and intact performance with facial expressions. In this single-case study we assessed a 30-year-old patient with autism spectrum disorder, without intellectual disability, and a healthy control group (n = 30) with four tasks of basic and complex emotion recognition through face and body movements, and two non-emotional control tasks. To analyze the dissociation between facial and body expressions, we used Crawford and Garthwaite's operational criteria, and we compared the patient and the control group performance with a modified one-tailed t-test designed specifically for single-case studies. There were no statistically significant differences between the patient's and the control group's performances on the non-emotional body movement task or the facial perception task. For both kinds of emotions (basic and complex) when the patient's performance was compared to the control group's, statistically significant differences were only observed for the recognition of body expressions. There were no significant differences between the patient's and the control group's correct answers for emotional facial stimuli. Our results showed a profile of impaired emotion recognition through body expressions and intact performance with facial expressions. This is the first case study that describes the existence of this kind of dissociation pattern between facial and body expressions of basic and complex emotions.

  15. A History of Abuse and Operative Delivery

    DEFF Research Database (Denmark)

    Schei, Berit; Lukasse, Mirjam; Ryding, Elsa Lena

    2014-01-01

    OBJECTIVE: The main aim of this study was to assess whether a history of abuse, reported during pregnancy, was associated with an operative delivery. Secondly, we assessed if the association varied according to the type of abuse and if the reported abuse had been experienced as a child or an adult...... and multinomial regression analysis were used to assess the associations. RESULTS: Among 3308 primiparous women, sexual abuse as an adult (≥ 18 years) increased the risk of an elective CS, Adjusted Odds Ratio 2.12 (1.28-3.49), and the likelihood for a non-obstetrically indicated CS, OR 3.74 (1.24-11.24). Women...... expressing current suffering from the reported adult sexual abuse had the highest risk for an elective CS, AOR 4.07 (1.46-11.3). Neither physical abuse (in adulthood or childhood sexual abuse in childhood increased the risk of any operative delivery among primiparous women. Among 3416...

  16. Guidance for RNA-seq co-expression network construction and analysis: safety in numbers.

    Science.gov (United States)

    Ballouz, S; Verleyen, W; Gillis, J

    2015-07-01

    RNA-seq co-expression analysis is in its infancy and reasonable practices remain poorly defined. We assessed a variety of RNA-seq expression data to determine factors affecting functional connectivity and topology in co-expression networks. We examine RNA-seq co-expression data generated from 1970 RNA-seq samples using a Guilt-By-Association framework, in which genes are assessed for the tendency of co-expression to reflect shared function. Minimal experimental criteria to obtain performance on par with microarrays were >20 samples with read depth >10 M per sample. While the aggregate network constructed shows good performance (area under the receiver operator characteristic curve ∼0.71), the dependency on number of experiments used is nearly identical to that present in microarrays, suggesting thousands of samples are required to obtain 'gold-standard' co-expression. We find a major topological difference between RNA-seq and microarray co-expression in the form of low overlaps between hub-like genes from each network due to changes in the correlation of expression noise within each technology. jgillis@cshl.edu or sballouz@cshl.edu Networks are available at: http://gillislab.labsites.cshl.edu/supplements/rna-seq-networks/ and supplementary data are available at Bioinformatics online. © The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com.

  17. Operating Comfort Prediction Model of Human-Machine Interface Layout for Cabin Based on GEP.

    Science.gov (United States)

    Deng, Li; Wang, Guohua; Chen, Bo

    2015-01-01

    In view of the evaluation and decision-making problem of human-machine interface layout design for cabin, the operating comfort prediction model is proposed based on GEP (Gene Expression Programming), using operating comfort to evaluate layout scheme. Through joint angles to describe operating posture of upper limb, the joint angles are taken as independent variables to establish the comfort model of operating posture. Factor analysis is adopted to decrease the variable dimension; the model's input variables are reduced from 16 joint angles to 4 comfort impact factors, and the output variable is operating comfort score. The Chinese virtual human body model is built by CATIA software, which will be used to simulate and evaluate the operators' operating comfort. With 22 groups of evaluation data as training sample and validation sample, GEP algorithm is used to obtain the best fitting function between the joint angles and the operating comfort; then, operating comfort can be predicted quantitatively. The operating comfort prediction result of human-machine interface layout of driller control room shows that operating comfort prediction model based on GEP is fast and efficient, it has good prediction effect, and it can improve the design efficiency.

  18. Operator expansions in the minimal subtraction scheme. II. Explicit formulas for coefficient functions

    International Nuclear Information System (INIS)

    Chetyrkin, K.G.

    1989-01-01

    It is shown in an arbitrary model that the coefficient functions of the operator expansion (renormalized in the minimal subtraction scheme) are finite. Explicit formulas convenient for calculating them in practice are obtained. The gluing method and the formalism of the R* operation are used to transform the formulas in such a way that the coefficient functions can be expressed in terms of ordinary diagrams containing neither nonstandard propagators nor an additional loop integration. An important feature of the representation for the coefficient functions is that the R* operation, which subtracts simultaneously the ultraviolet and infrared divergences, guarantees the existence of the coefficient functions in the limit when the dimensional regularization is lifted without any restrictions

  19. Evidence for the negative regulation of phytase gene expression in Streptomyces lividans and Streptomyces coelicolor.

    Science.gov (United States)

    Boukhris, Ines; Dulermo, Thierry; Chouayekh, Hichem; Virolle, Marie-Joëlle

    2016-01-01

    Sco7697, a gene encoding a phytase, enzyme able to degrade phytate (myo-inositol 1,2,3,4,5,6-hexakis phosphate), the most abundant phosphorus storing compound in plants is present in the genome of S. coelicolor, a soil born bacteria with a saprophytic lifestyle. The expression of this gene was previously shown to be induced in conditions of Pi limitation by the response regulator PhoP binding to an operator sequence, the PHO box, located upstream of the -35 promoter sequence. A close examination of the promoter region of sco7697 revealed the presence of another putative operator site, a Direct Repeat (DR), located downstream of the -10 promoter sequence. In order to determine whether this DR played a role in regulation of sco7697 expression, different variants of the phytase gene promoter region were transcriptionally fused to the ß-glucuronidase reporter gene (GUS). As expected, deletion of the PHO box led to abolition of sco7697 induction in conditions of Pi limitation. Interestingly, alteration of the DR correlated with a dramatic increase of GUS expression but only when PhoP was present. These results demonstrated that this DR is the site of strong negative regulation by an unknown repressor. The latter would impede the necessary activation of phytase expression by PhoP. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  20. Using business intelligence for efficient inter-facility patient transfer.

    Science.gov (United States)

    Haque, Waqar; Derksen, Beth Ann; Calado, Devin; Foster, Lee

    2015-01-01

    In the context of inter-facility patient transfer, a transfer operator must be able to objectively identify a destination which meets the needs of a patient, while keeping in mind each facility's limitations. We propose a solution which uses Business Intelligence (BI) techniques to analyze data related to healthcare infrastructure and services, and provides a web based system to identify optimal destination(s). The proposed inter-facility transfer system uses a single data warehouse with an Online Analytical Processing (OLAP) cube built on top that supplies analytical data to multiple reports embedded in web pages. The data visualization tool includes map based navigation of the health authority as well as an interactive filtering mechanism which finds facilities meeting the selected criteria. The data visualization is backed by an intuitive data entry web form which safely constrains the data, ensuring consistency and a single version of truth. The overall time required to identify the destination for inter-facility transfers is reduced from hours to a few minutes with this interactive solution.