WorldWideScience

Sample records for exponential growth curve

  1. Academia-industry collaboration feeds exponential growth curve

    CERN Document Server

    Jones Bey Hassaun, A

    2004-01-01

    The use of silicon strip detectors in high-energy particle tracking is discussed. The functional strength of silicon for high-energy particle physics as well as astrophysics lies in the ability to detect passage of charged particles with micron-scale spatial resolution. In addition to vertex detection, silicon strip detectors also provide full tracking detection to include momentum determination of particles in the magnetic field. Even if silicon detectors for basic science applications do not continue to grow larger, exponential growth of the technology for terrestrial commercial applications is likely to follow a healthy growth curve, as researchers continue to adapt silicon detector technology for low- dose medical x-ray imaging. (Edited abstract)

  2. Real-Time Exponential Curve Fits Using Discrete Calculus

    Science.gov (United States)

    Rowe, Geoffrey

    2010-01-01

    An improved solution for curve fitting data to an exponential equation (y = Ae(exp Bt) + C) has been developed. This improvement is in four areas -- speed, stability, determinant processing time, and the removal of limits. The solution presented avoids iterative techniques and their stability errors by using three mathematical ideas: discrete calculus, a special relationship (be tween exponential curves and the Mean Value Theorem for Derivatives), and a simple linear curve fit algorithm. This method can also be applied to fitting data to the general power law equation y = Ax(exp B) + C and the general geometric growth equation y = Ak(exp Bt) + C.

  3. Universality in stochastic exponential growth.

    Science.gov (United States)

    Iyer-Biswas, Srividya; Crooks, Gavin E; Scherer, Norbert F; Dinner, Aaron R

    2014-07-11

    Recent imaging data for single bacterial cells reveal that their mean sizes grow exponentially in time and that their size distributions collapse to a single curve when rescaled by their means. An analogous result holds for the division-time distributions. A model is needed to delineate the minimal requirements for these scaling behaviors. We formulate a microscopic theory of stochastic exponential growth as a Master Equation that accounts for these observations, in contrast to existing quantitative models of stochastic exponential growth (e.g., the Black-Scholes equation or geometric Brownian motion). Our model, the stochastic Hinshelwood cycle (SHC), is an autocatalytic reaction cycle in which each molecular species catalyzes the production of the next. By finding exact analytical solutions to the SHC and the corresponding first passage time problem, we uncover universal signatures of fluctuations in exponential growth and division. The model makes minimal assumptions, and we describe how more complex reaction networks can reduce to such a cycle. We thus expect similar scalings to be discovered in stochastic processes resulting in exponential growth that appear in diverse contexts such as cosmology, finance, technology, and population growth.

  4. An Exponential Growth Learning Trajectory: Students' Emerging Understanding of Exponential Growth through Covariation

    Science.gov (United States)

    Ellis, Amy B.; Ozgur, Zekiye; Kulow, Torrey; Dogan, Muhammed F.; Amidon, Joel

    2016-01-01

    This article presents an Exponential Growth Learning Trajectory (EGLT), a trajectory identifying and characterizing middle grade students' initial and developing understanding of exponential growth as a result of an instructional emphasis on covariation. The EGLT explicates students' thinking and learning over time in relation to a set of tasks…

  5. Background does not significantly affect power-exponential fitting of gastric emptying curves

    International Nuclear Information System (INIS)

    Jonderko, K.

    1987-01-01

    Using a procedure enabling the assessment of background radiation, research was done to elucidate the course of changes in background activity during gastric emptying measurements. Attention was focused on the changes in the shape of power-exponential fitted gastric emptying curves after correction for background was performed. The observed pattern of background counts allowed to explain the shifts of the parameters characterizing power-exponential curves connected with background correction. It was concluded that background had a negligible effect on the power-exponential fitting of gastric emptying curves. (author)

  6. Phenomenology of stochastic exponential growth

    Science.gov (United States)

    Pirjol, Dan; Jafarpour, Farshid; Iyer-Biswas, Srividya

    2017-06-01

    Stochastic exponential growth is observed in a variety of contexts, including molecular autocatalysis, nuclear fission, population growth, inflation of the universe, viral social media posts, and financial markets. Yet literature on modeling the phenomenology of these stochastic dynamics has predominantly focused on one model, geometric Brownian motion (GBM), which can be described as the solution of a Langevin equation with linear drift and linear multiplicative noise. Using recent experimental results on stochastic exponential growth of individual bacterial cell sizes, we motivate the need for a more general class of phenomenological models of stochastic exponential growth, which are consistent with the observation that the mean-rescaled distributions are approximately stationary at long times. We show that this behavior is not consistent with GBM, instead it is consistent with power-law multiplicative noise with positive fractional powers. Therefore, we consider this general class of phenomenological models for stochastic exponential growth, provide analytical solutions, and identify the important dimensionless combination of model parameters, which determines the shape of the mean-rescaled distribution. We also provide a prescription for robustly inferring model parameters from experimentally observed stochastic growth trajectories.

  7. Studying the method of linearization of exponential calibration curves

    International Nuclear Information System (INIS)

    Bunzh, Z.A.

    1989-01-01

    The results of study of the method for linearization of exponential calibration curves are given. The calibration technique and comparison of the proposed method with piecewise-linear approximation and power series expansion, are given

  8. From Experiment to Theory: What Can We Learn from Growth Curves?

    Science.gov (United States)

    Kareva, Irina; Karev, Georgy

    2018-01-01

    Finding an appropriate functional form to describe population growth based on key properties of a described system allows making justified predictions about future population development. This information can be of vital importance in all areas of research, ranging from cell growth to global demography. Here, we use this connection between theory and observation to pose the following question: what can we infer about intrinsic properties of a population (i.e., degree of heterogeneity, or dependence on external resources) based on which growth function best fits its growth dynamics? We investigate several nonstandard classes of multi-phase growth curves that capture different stages of population growth; these models include hyperbolic-exponential, exponential-linear, exponential-linear-saturation growth patterns. The constructed models account explicitly for the process of natural selection within inhomogeneous populations. Based on the underlying hypotheses for each of the models, we identify whether the population that it best fits by a particular curve is more likely to be homogeneous or heterogeneous, grow in a density-dependent or frequency-dependent manner, and whether it depends on external resources during any or all stages of its development. We apply these predictions to cancer cell growth and demographic data obtained from the literature. Our theory, if confirmed, can provide an additional biomarker and a predictive tool to complement experimental research.

  9. Flow of viscous fluid along an exponentially stretching curved surface

    Directory of Open Access Journals (Sweden)

    N.F. Okechi

    Full Text Available In this paper, we present the boundary layer analysis of flow induced by rapidly stretching curved surface with exponential velocity. The governing boundary value problem is reduced into self-similar form using a new similarity transformation. The resulting equations are solved numerically using shooting and Runge-Kutta methods. The numerical results depicts that the fluid velocity as well as the skin friction coefficient increases with the surface curvature, similar trend is also observed for the pressure. The dimensionless wall shear stress defined for this problem is greater than that of a linearly stretching curved surface, but becomes comparably less for a surface stretching with a power-law velocity. In addition, the result for the plane surface is a special case of this study when the radius of curvature of the surface is sufficiently large. The numerical investigations presented in terms of the graphs are interpreted with the help of underlying physics of the fluid flow and the consequences arising from the curved geometry. Keywords: Boundary layer flow, Curved surface, Exponential stretching, Curvature

  10. Trajectory Optimization of Spray Painting Robot for Complex Curved Surface Based on Exponential Mean Bézier Method

    Directory of Open Access Journals (Sweden)

    Wei Chen

    2017-01-01

    Full Text Available Automated tool trajectory planning for spray painting robots is still a challenging problem, especially for a large complex curved surface. This paper presents a new method of trajectory optimization for spray painting robot based on exponential mean Bézier method. The definition and the three theorems of exponential mean Bézier curves are discussed. Then a spatial painting path generation method based on exponential mean Bézier curves is developed. A new simple algorithm for trajectory optimization on complex curved surfaces is introduced. A golden section method is adopted to calculate the values. The experimental results illustrate that the exponential mean Bézier curves enhanced flexibility of the path planning, and the trajectory optimization algorithm achieved satisfactory performance. This method can also be extended to other applications.

  11. Exponential growth for self-reproduction in a catalytic reaction network: relevance of a minority molecular species and crowdedness

    Science.gov (United States)

    Kamimura, Atsushi; Kaneko, Kunihiko

    2018-03-01

    Explanation of exponential growth in self-reproduction is an important step toward elucidation of the origins of life because optimization of the growth potential across rounds of selection is necessary for Darwinian evolution. To produce another copy with approximately the same composition, the exponential growth rates for all components have to be equal. How such balanced growth is achieved, however, is not a trivial question, because this kind of growth requires orchestrated replication of the components in stochastic and nonlinear catalytic reactions. By considering a mutually catalyzing reaction in two- and three-dimensional lattices, as represented by a cellular automaton model, we show that self-reproduction with exponential growth is possible only when the replication and degradation of one molecular species is much slower than those of the others, i.e., when there is a minority molecule. Here, the synergetic effect of molecular discreteness and crowding is necessary to produce the exponential growth. Otherwise, the growth curves show superexponential growth because of nonlinearity of the catalytic reactions or subexponential growth due to replication inhibition by overcrowding of molecules. Our study emphasizes that the minority molecular species in a catalytic reaction network is necessary for exponential growth at the primitive stage of life.

  12. Exponential Growth and the Shifting Global Center of Gravity of Science Production, 1900-2011

    Science.gov (United States)

    Zhang, Liang; Powell, Justin J. W.; Baker, David P.

    2015-01-01

    Long historical trends in scientific discovery led mid-20th century scientometricians to mark the advent of "big science"--extensive science production--and predicted that over the next few decades, the exponential growth would slow, resulting in lower rates of increase in production at the upper limit of a logistic curve. They were…

  13. Exponential models applied to automated processing of radioimmunoassay standard curves

    International Nuclear Information System (INIS)

    Morin, J.F.; Savina, A.; Caroff, J.; Miossec, J.; Legendre, J.M.; Jacolot, G.; Morin, P.P.

    1979-01-01

    An improved computer processing is described for fitting of radio-immunological standard curves by means of an exponential model on a desk-top calculator. This method has been applied to a variety of radioassays and the results are in accordance with those obtained by more sophisticated models [fr

  14. Exponential rarefaction of real curves with many components

    OpenAIRE

    Gayet , Damien; Welschinger , Jean-Yves

    2011-01-01

    21 pages; Given a positive real Hermitian holomorphic line bundle L over a smooth real projective manifold X, the space of real holomorphic sections of the bundle L^d inherits for every positive integer d a L^2 scalar product which induces a Gaussian measure. When X is a curve or a surface, we estimate the volume of the cone of real sections whose vanishing locus contains many real components. In particular, the volume of the cone of maximal real sections decreases exponentially as d grows to...

  15. Academic Sacred Cows and Exponential Growth.

    Science.gov (United States)

    Heterick, Robert C., Jr.

    1991-01-01

    The speech notes the linear growth of resources versus the exponential growth of costs in higher education. It identifies opportunities arising from information technology to transform teaching and learning through creation of a new scholarly information delivery system. An integrated triad of communications, computing, and library organizations…

  16. When economic growth is less than exponential

    DEFF Research Database (Denmark)

    Groth, Christian; Koch, Karl-Josef; Steger, Thomas

    2010-01-01

    This paper argues that growth theory needs a more general notion of "regularity" than that of exponential growth. We suggest that paths along which the rate of decline of the growth rate is proportional to the growth rate itself deserve attention. This opens up for considering a richer set...

  17. When Economic Growth is Less than Exponential

    DEFF Research Database (Denmark)

    Groth, Christian; Koch, Karl-Josef; Steger, Thomas M.

    This paper argues that growth theory needs a more general notion of "regularity" than that of exponential growth. We suggest that paths along which the rate of decline of the growth rate is proportional to the growth rate itself deserve attention. This opens up for considering a richer set...

  18. Rational quadratic trigonometric Bézier curve based on new basis with exponential functions

    Directory of Open Access Journals (Sweden)

    Wu Beibei

    2017-06-01

    Full Text Available We construct a rational quadratic trigonometric Bézier curve with four shape parameters by introducing two exponential functions into the trigonometric basis functions in this paper. It has the similar properties as the rational quadratic Bézier curve. For given control points, the shape of the curve can be flexibly adjusted by changing the shape parameters and the weight. Some conics can be exactly represented when the control points, the shape parameters and the weight are chosen appropriately. The C0, C1 and C2 continuous conditions for joining two constructed curves are discussed. Some examples are given.

  19. Exponential Growth of Nonlinear Ballooning Instability

    International Nuclear Information System (INIS)

    Zhu, P.; Hegna, C. C.; Sovinec, C. R.

    2009-01-01

    Recent ideal magnetohydrodynamic (MHD) theory predicts that a perturbation evolving from a linear ballooning instability will continue to grow exponentially in the intermediate nonlinear phase at the same linear growth rate. This prediction is confirmed in ideal MHD simulations. When the Lagrangian compression, a measure of the ballooning nonlinearity, becomes of the order of unity, the intermediate nonlinear phase is entered, during which the maximum plasma displacement amplitude as well as the total kinetic energy continues to grow exponentially at the rate of the corresponding linear phase.

  20. The Western Africa ebola virus disease epidemic exhibits both global exponential and local polynomial growth rates.

    Science.gov (United States)

    Chowell, Gerardo; Viboud, Cécile; Hyman, James M; Simonsen, Lone

    2015-01-21

    While many infectious disease epidemics are initially characterized by an exponential growth in time, we show that district-level Ebola virus disease (EVD) outbreaks in West Africa follow slower polynomial-based growth kinetics over several generations of the disease. We analyzed epidemic growth patterns at three different spatial scales (regional, national, and subnational) of the Ebola virus disease epidemic in Guinea, Sierra Leone and Liberia by compiling publicly available weekly time series of reported EVD case numbers from the patient database available from the World Health Organization website for the period 05-Jan to 17-Dec 2014. We found significant differences in the growth patterns of EVD cases at the scale of the country, district, and other subnational administrative divisions. The national cumulative curves of EVD cases in Guinea, Sierra Leone, and Liberia show periods of approximate exponential growth. In contrast, local epidemics are asynchronous and exhibit slow growth patterns during 3 or more EVD generations, which can be better approximated by a polynomial than an exponential function. The slower than expected growth pattern of local EVD outbreaks could result from a variety of factors, including behavior changes, success of control interventions, or intrinsic features of the disease such as a high level of clustering. Quantifying the contribution of each of these factors could help refine estimates of final epidemic size and the relative impact of different mitigation efforts in current and future EVD outbreaks.

  1. Rethinking Economics and Education: Exponential Growth and Post-Growth Strategies

    Science.gov (United States)

    Irwin, Ruth

    2017-01-01

    Education is increasingly vocational and structured to serve the ongoing exponential increase in economic growth. Climate change is an outcome of these same economic values and praxes. Attempts to shift these values and our approach to technology are continually absorbed and overcome by the pressing motif of economic growth. In this article, Ruth…

  2. Assessment of Ex-Vitro Anaerobic Digestion Kinetics of Crop Residues Through First Order Exponential Models: Effect of LAG Phase Period and Curve Factor

    Directory of Open Access Journals (Sweden)

    Abdul Razaque Sahito

    2013-04-01

    Full Text Available Kinetic studies of AD (Anaerobic Digestion process are useful to predict the performance of digesters and design appropriate digesters and also helpful in understanding inhibitory mechanisms of biodegradation. The aim of this study was to assess the anaerobic kinetics of crop residues digestion with buffalo dung. Seven crop residues namely, bagasse, banana plant waste, canola straw, cotton stalks, rice straw, sugarcane trash and wheat straw were selected from the field and were analyzed on MC (Moisture Contents, TS (Total Solids and VS (Volatile Solids with standard methods. In present study, three first order exponential models namely exponential model, exponential lag phase model and exponential curve factor model were used to assess the kinetics of the AD process of crop residues and the effect of lag phase and curve factor was analyzed based on statistical hypothesis testing and on information theory. Assessment of kinetics of the AD of crop residues and buffalo dung follows the first order kinetics. Out of the three models, the simple exponential model was the poorest model, while the first order exponential curve factor model is the best fit model. In addition to statistical hypothesis testing, the exponential curve factor model has least value of AIC (Akaike's Information Criterion and can generate methane production data more accurately. Furthermore, there is an inverse linear relationship between the lag phase period and the curve factor.

  3. Assessment of ex-vitro anaerobic digestion kinetics of crop residues through first order exponential models: effect of lag phase period and curve factor

    International Nuclear Information System (INIS)

    Sahito, A.R.; Brohi, K.M.

    2013-01-01

    Kinetic studies of AD (Anaerobic Digestion) process are useful to predict the performance of digesters and design appropriate digesters and also helpful in understanding inhibitory mechanisms of biodegradation. The aim of this study was to assess the anaerobic kinetics of crop residues digestion with buffalo dung. Seven crop residues namely, bagasse, banana plant waste, canola straw, cotton stalks, rice straw, sugarcane trash and wheat straw were selected from the field and were analyzed on MC (Moisture Contents), TS (Total Solids) and VS (Volatile Solids) with standard methods. In present study, three first order exponential models namely exponential model, exponential lag phase model and exponential curve factor model were used to assess the kinetics of the AD process of crop residues and the effect of lag phase and curve factor was analyzed based on statistical hypothesis testing and on information theory. Assessment of kinetics of the AD of crop residues and buffalo dung follows the first order kinetics. Out of the three models, the simple exponential model was the poorest model, while the first order exponential curve factor model is the best fit model. In addition to statistical hypothesis testing, the exponential curve factor model has least value of AIC (Akaike's Information Criterion) and can generate methane production data more accurately. Furthermore, there is an inverse linear relationship between the lag phase period and the curve factor. (author)

  4. A simple derivation of r* for curved exponential families

    DEFF Research Database (Denmark)

    Jensen, Jens Ledet

    1997-01-01

    For curved exponential families we consider modified likelihood ratio statistics of the form rL = r + log (u/r)/r, where r is the signed root of the likelihood ratio statistic. We are testing a one-dimensional hypothesis, but in order to specify approximate ancillary statistics we consider the test...... as one in a series of tests. By requiring asymptotic independence and asymptotic normality of the test statistics in a large deviation region there is a particular choice of the statistic u which suggests itself. The derivation of this result is quite simple, only involving a standard saddlepoint...... approximation followed by a transformation. We give explicit formulas for the statistic u, and include a discussion of the case where some coordinates of the underlying variable are lattice....

  5. Pre-exponential factor in general order kinetics of thermoluminescence and its influence on glow curves

    International Nuclear Information System (INIS)

    Sunta, C.M.; Ayta, W.E.F.; Chen, R.; Watanabe, S.

    1997-01-01

    A model of thermoluminescence kinetics based on a physically meaningful approach shows that the glow curve shapes undergo systematic changes with the change of trap occupancy (dose). In terms of the general order kinetics model it means that the kinetic order changes with sample dose. In parallel to the kinetic order, the pre-exponential factor also changes. In contrast to these results the glow curves calculated from the general order kinetics model show that the peak shape remains nearly constant when the trap occupancy is changed. When appropriately defined, the pre-exponential factor also has a fixed value independent of trap occupancy. In these respects the general order kinetics model, though empirical, seems to describe the glow peak behaviour quite successfully. However, regarding the peak temperature the theoretical results both from the physical as well as the empirical model seem to diverge from the experimental observations when the experimentally determined kinetics is non-first order. (author)

  6. Reduced heme levels underlie the exponential growth defect of the Shewanella oneidensis hfq mutant.

    Directory of Open Access Journals (Sweden)

    Christopher M Brennan

    Full Text Available The RNA chaperone Hfq fulfills important roles in small regulatory RNA (sRNA function in many bacteria. Loss of Hfq in the dissimilatory metal reducing bacterium Shewanella oneidensis strain MR-1 results in slow exponential phase growth and a reduced terminal cell density at stationary phase. We have found that the exponential phase growth defect of the hfq mutant in LB is the result of reduced heme levels. Both heme levels and exponential phase growth of the hfq mutant can be completely restored by supplementing LB medium with 5-aminolevulinic acid (5-ALA, the first committed intermediate synthesized during heme synthesis. Increasing expression of gtrA, which encodes the enzyme that catalyzes the first step in heme biosynthesis, also restores heme levels and exponential phase growth of the hfq mutant. Taken together, our data indicate that reduced heme levels are responsible for the exponential growth defect of the S. oneidensis hfq mutant in LB medium and suggest that the S. oneidensis hfq mutant is deficient in heme production at the 5-ALA synthesis step.

  7. Financing exponential growth at H3

    OpenAIRE

    Silva, João Ricardo Ferreira Hipolito da

    2012-01-01

    H3 is a fast-food chain that introduced the concept of gourmet hamburgers in the Portuguese market. This case-study illustrates its financing strategy that supported an exponential growth represented by opening 33 restaurants within approximately 3 years of its inception. H3 is now faced with the challenge of structuring its foreign ventures and change its financial approach. The main covered topics are the options an entrepreneur has for financing a new venture and how it evolves along th...

  8. Growth curves for twins in Slovenia.

    Science.gov (United States)

    Bricelj, Katja; Blickstein, Isaac; Bržan-Šimenc, Gabrijela; Janša, Vid; Lučovnik, Miha; Verdenik, Ivan; Trojner-Bregar, Andreja; Tul, Nataša

    2017-02-01

    Abnormalities of fetal growth are more common in twins. We introduce the growth curves for monitoring fetal growth in twin pregnancies in Slovenia. Slovenian National Perinatal Information System for the period between 2002 and 2010 was used to calculate birth weight percentiles for all live born twins for each week from 22nd to 40th week. The calculated percentiles of birth weight for all live-born twins in Slovenia served as the basis for drawing 'growth' curves. The calculated growth curves for twins will help accurately diagnose small or large twin fetuses for their gestational age in the native central European population.

  9. Noise suppress or express exponential growth for hybrid Hopfield neural networks

    International Nuclear Information System (INIS)

    Zhu Song; Shen Yi; Chen Guici

    2010-01-01

    In this Letter, we will show that noise can make the given hybrid Hopfield neural networks whose solution may grows exponentially become the new stochastic hybrid Hopfield neural networks whose solution will grows at most polynomially. On the other hand, we will also show that noise can make the given hybrid Hopfield neural networks whose solution grows at most polynomially become the new stochastic hybrid Hopfield neural networks whose solution will grows at exponentially. In other words, we will reveal that the noise can suppress or express exponential growth for hybrid Hopfield neural networks.

  10. The mechanism of double-exponential growth in hyper-inflation

    Science.gov (United States)

    Mizuno, T.; Takayasu, M.; Takayasu, H.

    2002-05-01

    Analyzing historical data of price indices, we find an extraordinary growth phenomenon in several examples of hyper-inflation in which, price changes are approximated nicely by double-exponential functions of time. In order to explain such behavior we introduce the general coarse-graining technique in physics, the Monte Carlo renormalization group method, to the price dynamics. Starting from a microscopic stochastic equation describing dealers’ actions in open markets, we obtain a macroscopic noiseless equation of price consistent with the observation. The effect of auto-catalytic shortening of characteristic time caused by mob psychology is shown to be responsible for the double-exponential behavior.

  11. Hemopoietic stem-cell compartment of the SCID mouse: Double-exponential survival curve after γ irradiation

    International Nuclear Information System (INIS)

    Taniguchi, Satoshi; Hirabayashi, Yoko; Inoue, Tohru; Kanisawa, Masayoshi; Sasaki, Hideki; Komatsu, Kenshi; Mori, K.J.

    1993-01-01

    It has been reported that SCID (severe combined immunodeficiency, scid/scid) mice are more radiosensitive than normal mice. In the present studies, graded doses of radiation were given to bone marrow cells from SCID mice, and double-exponential survival curves were observed for day-9 and day-12 colony-forming units in the spleen (CFU-S). Single-exponential curves were found for SCID CFU in in vitro assays for granulocyte/macrophage-CFUs and erythroid burst-forming units, as reported elsewhere. Since the size of this more resistant fraction seems to decrease with stem-cell maturation, the finding implies that this fraction is a primitive subpopulation of the stem-cell compartment. The mean lethal dose (D 0 ), however, of this less sensitive SCID CFU-S is much less than the D 0 of regular CFU-S in normal littermates. Spleen colonies produced by SCID bone marrow were relatively small and abortive. The size of these colonies decreased nearly exponentially with increasing doses of radiation. These colonies produced by the sensitive fraction have disappeared, being killed by a relatively low dose of radiation. This observation might account for the high lymphomagenesis arising from primitive hemopoietic stem cells in SCID mice, because the smallness of the colonies suggests that there is unrepaired or misrepaired damage. Furthermore, this less sensitive fraction might be a source of the open-quotes leakyclose quotes change of T and B cells, possibly due to the induction of an equivocal repair system which appears in the later stages of life in the SCID mice. 34 refs., 5 figs., 3 tabs

  12. Growth curves for Laron syndrome.

    OpenAIRE

    Laron, Z; Lilos, P; Klinger, B

    1993-01-01

    Growth curves for children with Laron syndrome were constructed on the basis of repeated measurements made throughout infancy, childhood, and puberty in 24 (10 boys, 14 girls) of the 41 patients with this syndrome investigated in our clinic. Growth retardation was already noted at birth, the birth length ranging from 42 to 46 cm in the 12/20 available measurements. The postnatal growth curves deviated sharply from the normal from infancy on. Both sexes showed no clear pubertal spurt. Girls co...

  13. Growth curves for Laron syndrome.

    Science.gov (United States)

    Laron, Z; Lilos, P; Klinger, B

    1993-01-01

    Growth curves for children with Laron syndrome were constructed on the basis of repeated measurements made throughout infancy, childhood, and puberty in 24 (10 boys, 14 girls) of the 41 patients with this syndrome investigated in our clinic. Growth retardation was already noted at birth, the birth length ranging from 42 to 46 cm in the 12/20 available measurements. The postnatal growth curves deviated sharply from the normal from infancy on. Both sexes showed no clear pubertal spurt. Girls completed their growth between the age of 16-19 years to a final mean (SD) height of 119 (8.5) cm whereas the boys continued growing beyond the age of 20 years, achieving a final height of 124 (8.5) cm. At all ages the upper to lower body segment ratio was more than 2 SD above the normal mean. These growth curves constitute a model not only for primary, hereditary insulin-like growth factor-I (IGF-I) deficiency (Laron syndrome) but also for untreated secondary IGF-I deficiencies such as growth hormone gene deletion and idiopathic congenital isolated growth hormone deficiency. They should also be useful in the follow up of children with Laron syndrome treated with biosynthetic recombinant IGF-I. PMID:8333769

  14. The impact of accelerating faster than exponential population growth on genetic variation.

    Science.gov (United States)

    Reppell, Mark; Boehnke, Michael; Zöllner, Sebastian

    2014-03-01

    Current human sequencing projects observe an abundance of extremely rare genetic variation, suggesting recent acceleration of population growth. To better understand the impact of such accelerating growth on the quantity and nature of genetic variation, we present a new class of models capable of incorporating faster than exponential growth in a coalescent framework. Our work shows that such accelerated growth affects only the population size in the recent past and thus large samples are required to detect the models' effects on patterns of variation. When we compare models with fixed initial growth rate, models with accelerating growth achieve very large current population sizes and large samples from these populations contain more variation than samples from populations with constant growth. This increase is driven almost entirely by an increase in singleton variation. Moreover, linkage disequilibrium decays faster in populations with accelerating growth. When we instead condition on current population size, models with accelerating growth result in less overall variation and slower linkage disequilibrium decay compared to models with exponential growth. We also find that pairwise linkage disequilibrium of very rare variants contains information about growth rates in the recent past. Finally, we demonstrate that models of accelerating growth may substantially change estimates of present-day effective population sizes and growth times.

  15. Nonlinear Schrodinger elliptic systems involving exponential critical growth in R^2

    Directory of Open Access Journals (Sweden)

    Francisco S. B. Albuquerque Albuquerque

    2014-02-01

    Full Text Available This article concerns the existence and multiplicity of solutions for elliptic systems with weights, and nonlinearities having exponential critical growth. Our approach is based on the Trudinger-Moser inequality and on a minimax theorem.

  16. Growth Curves for Girls with Turner Syndrome

    Directory of Open Access Journals (Sweden)

    Fabio Bertapelli

    2014-01-01

    Full Text Available The objective of this study was to review the growth curves for Turner syndrome, evaluate the methodological and statistical quality, and suggest potential growth curves for clinical practice guidelines. The search was carried out in the databases Medline and Embase. Of 1006 references identified, 15 were included. Studies constructed curves for weight, height, weight/height, body mass index, head circumference, height velocity, leg length, and sitting height. The sample ranged between 47 and 1,565 (total = 6,273 girls aged 0 to 24 y, born between 1950 and 2006. The number of measures ranged from 580 to 9,011 (total = 28,915. Most studies showed strengths such as sample size, exclusion of the use of growth hormone and androgen, and analysis of confounding variables. However, the growth curves were restricted to height, lack of information about selection bias, limited distributional properties, and smoothing aspects. In conclusion, we observe the need to construct an international growth reference for girls with Turner syndrome, in order to provide support for clinical practice guidelines.

  17. Boundary curves of individual items in the distribution of total depressive symptom scores approximate an exponential pattern in a general population.

    Science.gov (United States)

    Tomitaka, Shinichiro; Kawasaki, Yohei; Ide, Kazuki; Akutagawa, Maiko; Yamada, Hiroshi; Furukawa, Toshiaki A; Ono, Yutaka

    2016-01-01

    Previously, we proposed a model for ordinal scale scoring in which individual thresholds for each item constitute a distribution by each item. This lead us to hypothesize that the boundary curves of each depressive symptom score in the distribution of total depressive symptom scores follow a common mathematical model, which is expressed as the product of the frequency of the total depressive symptom scores and the probability of the cumulative distribution function of each item threshold. To verify this hypothesis, we investigated the boundary curves of the distribution of total depressive symptom scores in a general population. Data collected from 21,040 subjects who had completed the Center for Epidemiologic Studies Depression Scale (CES-D) questionnaire as part of a national Japanese survey were analyzed. The CES-D consists of 20 items (16 negative items and four positive items). The boundary curves of adjacent item scores in the distribution of total depressive symptom scores for the 16 negative items were analyzed using log-normal scales and curve fitting. The boundary curves of adjacent item scores for a given symptom approximated a common linear pattern on a log normal scale. Curve fitting showed that an exponential fit had a markedly higher coefficient of determination than either linear or quadratic fits. With negative affect items, the gap between the total score curve and boundary curve continuously increased with increasing total depressive symptom scores on a log-normal scale, whereas the boundary curves of positive affect items, which are not considered manifest variables of the latent trait, did not exhibit such increases in this gap. The results of the present study support the hypothesis that the boundary curves of each depressive symptom score in the distribution of total depressive symptom scores commonly follow the predicted mathematical model, which was verified to approximate an exponential mathematical pattern.

  18. Boundary curves of individual items in the distribution of total depressive symptom scores approximate an exponential pattern in a general population

    Directory of Open Access Journals (Sweden)

    Shinichiro Tomitaka

    2016-10-01

    Full Text Available Background Previously, we proposed a model for ordinal scale scoring in which individual thresholds for each item constitute a distribution by each item. This lead us to hypothesize that the boundary curves of each depressive symptom score in the distribution of total depressive symptom scores follow a common mathematical model, which is expressed as the product of the frequency of the total depressive symptom scores and the probability of the cumulative distribution function of each item threshold. To verify this hypothesis, we investigated the boundary curves of the distribution of total depressive symptom scores in a general population. Methods Data collected from 21,040 subjects who had completed the Center for Epidemiologic Studies Depression Scale (CES-D questionnaire as part of a national Japanese survey were analyzed. The CES-D consists of 20 items (16 negative items and four positive items. The boundary curves of adjacent item scores in the distribution of total depressive symptom scores for the 16 negative items were analyzed using log-normal scales and curve fitting. Results The boundary curves of adjacent item scores for a given symptom approximated a common linear pattern on a log normal scale. Curve fitting showed that an exponential fit had a markedly higher coefficient of determination than either linear or quadratic fits. With negative affect items, the gap between the total score curve and boundary curve continuously increased with increasing total depressive symptom scores on a log-normal scale, whereas the boundary curves of positive affect items, which are not considered manifest variables of the latent trait, did not exhibit such increases in this gap. Discussion The results of the present study support the hypothesis that the boundary curves of each depressive symptom score in the distribution of total depressive symptom scores commonly follow the predicted mathematical model, which was verified to approximate an

  19. Measurement of cellular copper levels in Bacillus megaterium during exponential growth and sporulation.

    Science.gov (United States)

    Krueger, W B; Kolodziej, B J

    1976-01-01

    Both atomic absorption spectrophotometry (AAS) and neutron activation analysis have been utilized to determine cellular Cu levels in Bacillus megaterium ATCC 19213. Both methods were selected for their sensitivity to detection of nanogram quantities of Cu. Data from both methods demonstrated identical patterms of Cu uptake during exponenetial growth and sporulation. Late exponential phase cells contained less Cu than postexponential t2 cells while t5 cells contained amounts equivalent to exponential cells. The t11 phase-bright forespore containing cells had a higher Cu content than those of earlier time periods, and the free spores had the highest Cu content. Analysis of the culture medium by AAS corroborated these data by showing concomitant Cu uptake during exponential growth and into t2 postexponential phase of sporulation. From t2 to t4, Cu egressed from the cells followed by a secondary uptake during the maturation of phase-dark forespores into phase-bright forespores (t6--t9).

  20. Nonlinear Growth Curves in Developmental Research

    Science.gov (United States)

    Grimm, Kevin J.; Ram, Nilam; Hamagami, Fumiaki

    2011-01-01

    Developmentalists are often interested in understanding change processes, and growth models are the most common analytic tool for examining such processes. Nonlinear growth curves are especially valuable to developmentalists because the defining characteristics of the growth process such as initial levels, rates of change during growth spurts, and…

  1. Surface growth kinematics via local curve evolution

    KAUST Repository

    Moulton, Derek E.

    2012-11-18

    A mathematical framework is developed to model the kinematics of surface growth for objects that can be generated by evolving a curve in space, such as seashells and horns. Growth is dictated by a growth velocity vector field defined at every point on a generating curve. A local orthonormal basis is attached to each point of the generating curve and the velocity field is given in terms of the local coordinate directions, leading to a fully local and elegant mathematical structure. Several examples of increasing complexity are provided, and we demonstrate how biologically relevant structures such as logarithmic shells and horns emerge as analytical solutions of the kinematics equations with a small number of parameters that can be linked to the underlying growth process. Direct access to cell tracks and local orientation enables for connections to be made to the underlying growth process. © 2012 Springer-Verlag Berlin Heidelberg.

  2. Empirical Percentile Growth Curves with Z-scores Considering Seasonal Compensatory Growths for Japanese Thoroughbred Horses

    Science.gov (United States)

    ONODA, Tomoaki; YAMAMOTO, Ryuta; SAWAMURA, Kyohei; MURASE, Harutaka; NAMBO, Yasuo; INOUE, Yoshinobu; MATSUI, Akira; MIYAKE, Takeshi; HIRAI, Nobuhiro

    2013-01-01

    Percentile growth curves are often used as a clinical indicator to evaluate variations of children’s growth status. In this study, we propose empirical percentile growth curves using Z-scores adapted for Japanese Thoroughbred horses, with considerations of the seasonal compensatory growth that is a typical characteristic of seasonal breeding animals. We previously developed new growth curve equations for Japanese Thoroughbreds adjusting for compensatory growth. Individual horses and residual effects were included as random effects in the growth curve equation model and their variance components were estimated. Based on the Z-scores of the estimated variance components, empirical percentile growth curves were constructed. A total of 5,594 and 5,680 body weight and age measurements of male and female Thoroughbreds, respectively, and 3,770 withers height and age measurements were used in the analyses. The developed empirical percentile growth curves using Z-scores are computationally feasible and useful for monitoring individual growth parameters of body weight and withers height of young Thoroughbred horses, especially during compensatory growth periods. PMID:24834004

  3. The extracellular proteome of Rhizobium etli CE3 in exponential and stationary growth phase

    Directory of Open Access Journals (Sweden)

    Mendoza-Hernández Guillermo

    2010-10-01

    Full Text Available Abstract Background The extracellular proteome or secretome of symbiotic bacteria like Rhizobium etli is presumed to be a key element of their infection strategy and survival. Rhizobia infect the roots of leguminous plants and establish a mutually beneficial symbiosis. To find out the possible role of secreted proteins we analyzed the extracellular proteome of R. etli CE3 in the exponential and stationary growth phases in minimal medium, supplemented with succinate-ammonium. Results The extracellular proteins were obtained by phenol extraction and identified by LC-ESI MS/MS. We identified 192 and 191 proteins for the exponential and stationary phases respectively. Using the software Signal P, we predicted signal peptides for 12.95% and 35.60% of the proteins identified in the exponential and stationary phases, respectively, which could therefore be secreted by the Sec pathway. For the exponential growth phase, we found in abundance proteins like the ribosomal proteins, toxins and proteins belonging to the group "defence mechanisms". For the stationary growth phase, we found that the most abundant proteins were those with unknown function, and in many of these we identified characteristic domains of proteases and peptidases. Conclusions Our study provided the first dataset of the secretome of R. etli and its modifications, which may lead to novel insights into the adaptive response of different stages of growth. In addition, we found a high number of proteins with unknown function; these proteins could be analyzed in future research to elucidate their role in the extracellular proteome of R. etli.

  4. On the solar curve of growth of titanium

    International Nuclear Information System (INIS)

    Foy, R.

    1975-01-01

    Our purpose in the present work is to investigate whether or not the splitting of the solar curve of growth found in the case of iron applies to other elements. We show that, contrary to the solar curve of growth for iron, that for titanium is not split in its damping part; this result emphasizes that reference curves of growth have to be used very carefully in detailed analysis of stellar atmospheres. We confirm that the microturbulent velocity is very low in the solar photosphere, namely within the limits: 0.5 [de

  5. Intersection of the Exponential and Logarithmic Curves

    Science.gov (United States)

    Boukas, Andreas; Valahas, Theodoros

    2009-01-01

    The study of the number of intersection points of y = a[superscript x] and y = log[subscript a]x can be an interesting topic to present in a single-variable calculus class. In this article, the authors present a classroom presentation outline involving the basic algebra and the elementary calculus of the exponential and logarithmic functions. The…

  6. High-resolution time series of Pseudomonas aeruginosa gene expression and rhamnolipid secretion through growth curve synchronization

    Directory of Open Access Journals (Sweden)

    Xavier João B

    2011-06-01

    Full Text Available Abstract Background Online spectrophotometric measurements allow monitoring dynamic biological processes with high-time resolution. Contrastingly, numerous other methods require laborious treatment of samples and can only be carried out offline. Integrating both types of measurement would allow analyzing biological processes more comprehensively. A typical example of this problem is acquiring quantitative data on rhamnolipid secretion by the opportunistic pathogen Pseudomonas aeruginosa. P. aeruginosa cell growth can be measured by optical density (OD600 and gene expression can be measured using reporter fusions with a fluorescent protein, allowing high time resolution monitoring. However, measuring the secreted rhamnolipid biosurfactants requires laborious sample processing, which makes this an offline measurement. Results Here, we propose a method to integrate growth curve data with endpoint measurements of secreted metabolites that is inspired by a model of exponential cell growth. If serial diluting an inoculum gives reproducible time series shifted in time, then time series of endpoint measurements can be reconstructed using calculated time shifts between dilutions. We illustrate the method using measured rhamnolipid secretion by P. aeruginosa as endpoint measurements and we integrate these measurements with high-resolution growth curves measured by OD600 and expression of rhamnolipid synthesis genes monitored using a reporter fusion. Two-fold serial dilution allowed integrating rhamnolipid measurements at a ~0.4 h-1 frequency with high-time resolved data measured at a 6 h-1 frequency. We show how this simple method can be used in combination with mutants lacking specific genes in the rhamnolipid synthesis or quorum sensing regulation to acquire rich dynamic data on P. aeruginosa virulence regulation. Additionally, the linear relation between the ratio of inocula and the time-shift between curves produces high-precision measurements of

  7. Bacterial growth kinetics

    International Nuclear Information System (INIS)

    Boonkitticharoen, V.; Ehrhardt, J.C.; Kirchner, P.T.

    1989-01-01

    Quantitative measurement of bacterial growth may be made using a radioassay technique. This method measures, by scintillation counting, the 14 CO 2 derived from the bacterial metabolism of a 14 C-labeled substrate. Mathematical growth models may serve as reliable tools for estimation of the generation rate constant (or slope of the growth curve) and provide a basis for evaluating assay performance. Two models, i.e., exponential and logistic, are proposed. Both models yielded an accurate fit to the data from radioactive measurement of bacterial growth. The exponential model yielded high precision values of the generation rate constant, with an average relative standard deviation of 1.2%. Under most conditions the assay demonstrated no changes in the slopes of growth curves when the number of bacteria per inoculation was changed. However, the radiometric assay by scintillation method had a growth-inhibiting effect on a few strains of bacteria. The source of this problem was thought to be hypersensitivity to trace amounts of toluene remaining on the detector

  8. Rapid growth of seed black holes in the early universe by supra-exponential accretion.

    Science.gov (United States)

    Alexander, Tal; Natarajan, Priyamvada

    2014-09-12

    Mass accretion by black holes (BHs) is typically capped at the Eddington rate, when radiation's push balances gravity's pull. However, even exponential growth at the Eddington-limited e-folding time t(E) ~ few × 0.01 billion years is too slow to grow stellar-mass BH seeds into the supermassive luminous quasars that are observed when the universe is 1 billion years old. We propose a dynamical mechanism that can trigger supra-exponential accretion in the early universe, when a BH seed is bound in a star cluster fed by the ubiquitous dense cold gas flows. The high gas opacity traps the accretion radiation, while the low-mass BH's random motions suppress the formation of a slowly draining accretion disk. Supra-exponential growth can thus explain the puzzling emergence of supermassive BHs that power luminous quasars so soon after the Big Bang. Copyright © 2014, American Association for the Advancement of Science.

  9. Fast Modular Exponentiation and Elliptic Curve Group Operation in Maple

    Science.gov (United States)

    Yan, S. Y.; James, G.

    2006-01-01

    The modular exponentiation, y[equivalent to]x[superscript k](mod n) with x,y,k,n integers and n [greater than] 1; is the most fundamental operation in RSA and ElGamal public-key cryptographic systems. Thus the efficiency of RSA and ElGamal depends entirely on the efficiency of the modular exponentiation. The same situation arises also in elliptic…

  10. Exponential growth and atmospheric carbon dioxide

    International Nuclear Information System (INIS)

    Laurmann, J.A.; Rotty, R.M.

    1983-01-01

    The adequacy of assumptions required to project atmospheric CO 2 concentrations in time frames of practical importance is reviewed. Relevant issues concern the form assumed for future fossil fuel release, carbon cycle approximations, and the implications of revisions in fossil fuel patterns required to maintain atmospheric CO 2 levels below a chosen threshold. In general, we find that with a judiciously selected exponential fossil fuel release rate, and with a constant airborn fraction, we can estimate atmospheric CO 2 growth over the next 50 years based on essentially surprise free scenarios. Resource depletion effects must be included for projections beyond about 50 years, and on this time frame the constant airborne fraction approximation has to be questioned as well (especially in later years when the fossil fuel use begins to taper off). For projections for over 100 years, both energy demand scenarios and currently available carbon cycle models have sufficient uncertainties that atmospheric CO 2 levels derived from them are not much better than guesses

  11. An exponential growth model with decreasing r captures bottom-up effects on the population growth of Aphis glycines Matsumura (Hemiptera: Aphididae)

    NARCIS (Netherlands)

    Costamagna, A.C.; Werf, van der W.; Bianchi, F.J.J.A.; Landis, D.A.

    2007-01-01

    1 There is ample evidence that the life history and population dynamics of aphids are closely linked to plant phenology. Based on life table studies, it has been proposed that the growth of aphid populations could be modeled with an exponential growth model, with r decreasing linearly with time.

  12. Growth curve registration for evaluating salinity tolerance in barley

    KAUST Repository

    Meng, Rui

    2017-03-23

    Background: Smarthouses capable of non-destructive, high-throughput plant phenotyping collect large amounts of data that can be used to understand plant growth and productivity in extreme environments. The challenge is to apply the statistical tool that best analyzes the data to study plant traits, such as salinity tolerance, or plant-growth-related traits. Results: We derive family-wise salinity sensitivity (FSS) growth curves and use registration techniques to summarize growth patterns of HEB-25 barley families and the commercial variety, Navigator. We account for the spatial variation in smarthouse microclimates and in temporal variation across phenotyping runs using a functional ANOVA model to derive corrected FSS curves. From FSS, we derive corrected values for family-wise salinity tolerance, which are strongly negatively correlated with Na but not significantly with K, indicating that Na content is an important factor affecting salinity tolerance in these families, at least for plants of this age and grown in these conditions. Conclusions: Our family-wise methodology is suitable for analyzing the growth curves of a large number of plants from multiple families. The corrected curves accurately account for the spatial and temporal variations among plants that are inherent to high-throughput experiments.

  13. Growth curve registration for evaluating salinity tolerance in barley

    KAUST Repository

    Meng, Rui; Saade, Stephanie; Kurtek, Sebastian; Berger, Bettina; Brien, Chris; Pillen, Klaus; Tester, Mark A.; Sun, Ying

    2017-01-01

    Background: Smarthouses capable of non-destructive, high-throughput plant phenotyping collect large amounts of data that can be used to understand plant growth and productivity in extreme environments. The challenge is to apply the statistical tool that best analyzes the data to study plant traits, such as salinity tolerance, or plant-growth-related traits. Results: We derive family-wise salinity sensitivity (FSS) growth curves and use registration techniques to summarize growth patterns of HEB-25 barley families and the commercial variety, Navigator. We account for the spatial variation in smarthouse microclimates and in temporal variation across phenotyping runs using a functional ANOVA model to derive corrected FSS curves. From FSS, we derive corrected values for family-wise salinity tolerance, which are strongly negatively correlated with Na but not significantly with K, indicating that Na content is an important factor affecting salinity tolerance in these families, at least for plants of this age and grown in these conditions. Conclusions: Our family-wise methodology is suitable for analyzing the growth curves of a large number of plants from multiple families. The corrected curves accurately account for the spatial and temporal variations among plants that are inherent to high-throughput experiments.

  14. Nonlinear Growth Curves in Developmental Research

    Science.gov (United States)

    Grimm, Kevin J.; Ram, Nilam; Hamagami, Fumiaki

    2011-01-01

    Developmentalists are often interested in understanding change processes and growth models are the most common analytic tool for examining such processes. Nonlinear growth curves are especially valuable to developmentalists because the defining characteristics of the growth process such as initial levels, rates of change during growth spurts, and asymptotic levels can be estimated. A variety of growth models are described beginning with the linear growth model and moving to nonlinear models of varying complexity. A detailed discussion of nonlinear models is provided, highlighting the added insights into complex developmental processes associated with their use. A collection of growth models are fit to repeated measures of height from participants of the Berkeley Growth and Guidance Studies from early childhood through adulthood. PMID:21824131

  15. Genomic growth curves of an outbred pig population

    Directory of Open Access Journals (Sweden)

    Fabyano Fonseca e Silva

    2013-01-01

    Full Text Available In the current post-genomic era, the genetic basis of pig growth can be understood by assessing SNP marker effects and genomic breeding values (GEBV based on estimates of these growth curve parameters as phenotypes. Although various statistical methods, such as random regression (RR-BLUP and Bayesian LASSO (BL, have been applied to genomic selection (GS, none of these has yet been used in a growth curve approach. In this work, we compared the accuracies of RR-BLUP and BL using empirical weight-age data from an outbred F2 (Brazilian Piau X commercial population. The phenotypes were determined by parameter estimates using a nonlinear logistic regression model and the halothane gene was considered as a marker for evaluating the assumptions of the GS methods in relation to the genetic variation explained by each locus. BL yielded more accurate values for all of the phenotypes evaluated and was used to estimate SNP effects and GEBV vectors. The latter allowed the construction of genomic growth curves, which showed substantial genetic discrimination among animals in the final growth phase. The SNP effect estimates allowed identification of the most relevant markers for each phenotype, the positions of which were coincident with reported QTL regions for growth traits.

  16. PMAnalyzer: a new web interface for bacterial growth curve analysis.

    Science.gov (United States)

    Cuevas, Daniel A; Edwards, Robert A

    2017-06-15

    Bacterial growth curves are essential representations for characterizing bacteria metabolism within a variety of media compositions. Using high-throughput, spectrophotometers capable of processing tens of 96-well plates, quantitative phenotypic information can be easily integrated into the current data structures that describe a bacterial organism. The PMAnalyzer pipeline performs a growth curve analysis to parameterize the unique features occurring within microtiter wells containing specific growth media sources. We have expanded the pipeline capabilities and provide a user-friendly, online implementation of this automated pipeline. PMAnalyzer version 2.0 provides fast automatic growth curve parameter analysis, growth identification and high resolution figures of sample-replicate growth curves and several statistical analyses. PMAnalyzer v2.0 can be found at https://edwards.sdsu.edu/pmanalyzer/ . Source code for the pipeline can be found on GitHub at https://github.com/dacuevas/PMAnalyzer . Source code for the online implementation can be found on GitHub at https://github.com/dacuevas/PMAnalyzerWeb . dcuevas08@gmail.com. Supplementary data are available at Bioinformatics online. © The Author 2017. Published by Oxford University Press.

  17. Interactions of cosmic rays in the atmosphere: growth curves revisited

    Energy Technology Data Exchange (ETDEWEB)

    Obermeier, A.; Boyle, P.; Müller, D. [Enrico Fermi Institute, University of Chicago, Chicago, IL 60637 (United States); Hörandel, J., E-mail: a.obermeier@astro.ru.nl [Radboud Universiteit Nijmegen, 6525-HP Nijmegen (Netherlands)

    2013-12-01

    Measurements of cosmic-ray abundances on balloons are affected by interactions in the residual atmosphere above the balloon. Corrections for such interactions are particularly important for observations of rare secondary particles such as boron, antiprotons, and positrons. These corrections either can be calculated if the relevant cross sections in the atmosphere are known or may be empirically determined by extrapolation of the 'growth curves', i.e., the individual particle intensities as functions of atmospheric depth. The growth-curve technique is particularly attractive for long-duration balloon flights where the periodic daily altitude variations permit rather precise determinations of the corresponding particle intensity variations. We determine growth curves for nuclei from boron (Z = 5) to iron (Z = 26) using data from the 2006 Arctic balloon flight of the TRACER detector for cosmic-ray nuclei, and we compare the growth curves with predictions from published cross section values. In general, good agreement is observed. We then study the boron/carbon abundance ratio and derive a simple and energy-independent correction term for this ratio. We emphasize that the growth-curve technique can be developed further to provide highly accurate tests of published interaction cross section values.

  18. [Customized and non-customized French intrauterine growth curves. II - Comparison with existing curves and benefits of customization].

    Science.gov (United States)

    Ego, A; Prunet, C; Blondel, B; Kaminski, M; Goffinet, F; Zeitlin, J

    2016-02-01

    Our aim is to compare the new French EPOPé intrauterine growth curves, developed to address the guidelines 2013 of the French College of Obstetricians and Gynecologists, with reference curves currently used in France, and to evaluate the consequences of their adjustment for fetal sex and maternal characteristics. Eight intrauterine and birthweight curves, used in France were compared to the EPOPé curves using data from the French Perinatal Survey 2010. The influence of adjustment on the rate of SGA births and the characteristics of these births was analysed. Due to their birthweight values and distribution, the selected intrauterine curves are less suitable for births in France than the new curves. Birthweight curves led to low rates of SGA births from 4.3 to 8.5% compared to 10.0% with the EPOPé curves. The adjustment for maternal and fetal characteristics avoids the over-representation of girls among SGA births, and reclassifies 4% of births. Among births reclassified as SGA, the frequency of medical and obstetrical risk factors for growth restriction, smoking (≥10 cigarettes/day), and neonatal transfer is higher than among non-SGA births (P<0.01). The EPOPé curves are more suitable for French births than currently used curves, and their adjustment improves the identification of mothers and babies at risk of growth restriction and poor perinatal outcomes. Copyright © 2015 Elsevier Masson SAS. All rights reserved.

  19. Modeling Math Growth Trajectory--An Application of Conventional Growth Curve Model and Growth Mixture Model to ECLS K-5 Data

    Science.gov (United States)

    Lu, Yi

    2016-01-01

    To model students' math growth trajectory, three conventional growth curve models and three growth mixture models are applied to the Early Childhood Longitudinal Study Kindergarten-Fifth grade (ECLS K-5) dataset in this study. The results of conventional growth curve model show gender differences on math IRT scores. When holding socio-economic…

  20. Computerized tomography and head growth curve infantile macrocephaly with normal psychomotor development

    International Nuclear Information System (INIS)

    Eda, Isematsu; Kitahara, Tadashi; Takashima, Sachio; Takeshita, Kenzo

    1982-01-01

    Macrocephaly was defined as a head measuring larger than 98th percentile. We have evaluated CT findings and head growth curves in 25 infants with large heads. Ten (40%) of 25 infants with large heads were normal developmentally and neurologically. Five (20%) of those were mentally retarded. The other 10 infants (40%) included hydrocephalus (4 cases), malformation syndrome (3 cases), brain tumor (1 case), metabolic disorder (1 case) and degenerative disorder (1 case). Their head growth curves were typed as (I), (II) and (III): Type (I) (excessive head growth curve to 2 SDs above normal); Type (II) (head growth curve gradually approached to 2 SDs above normal); Type (III) (head growth curve parallel to 2 SDs above normal). Ten of macrocephaly with normal psychomotor development were studied clinically and radiologically in details. They were all male. CT pictures of those showed normal or various abnormal findings: ventricular dilatations, wide frontal and temporal subdural spaces, wide interhemispheric fissures, wide cerebral sulci, and large sylvian fissures. CT findings in 2 of those, which because normal after repeated CT examinations, resembled benign subdural collection. CT findings in one of those were external hydrocephalus. Head growth curves were obtained from 8 of those. Six cases revealed type (II) and two cases did type (III). The remaining 2 cases could not be followed up. We consider that CT findings of infants showed macrocephaly with normal psychomotor development reveals normal or various abnormal (ventricular dilatations, benign subdural collection, external hydrocephalus) and their head growth curves are not at least excessive. Infants with mental retardation showed similar CT findings and head growth curves as those with normal psychomotor development. It was difficult to distinguish normal from mentally retarded infants by either CT findings or head growth curves. (author)

  1. Forecasting Financial Extremes: A Network Degree Measure of Super-Exponential Growth.

    Directory of Open Access Journals (Sweden)

    Wanfeng Yan

    Full Text Available Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous overreaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential growth of stock prices, by measuring the degree of the price network, generated from the price time series. Twelve major international stock indices have been investigated. Error diagram tests show that this new indicator has strong predictive power for financial extremes, both peaks and troughs. By varying the parameters used to construct the error diagram, we show the predictive power is very robust. The new indicator has a better performance than the LPPL pattern recognition indicator.

  2. Forecasting Financial Extremes: A Network Degree Measure of Super-Exponential Growth.

    Science.gov (United States)

    Yan, Wanfeng; van Tuyll van Serooskerken, Edgar

    2015-01-01

    Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous overreaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential growth of stock prices, by measuring the degree of the price network, generated from the price time series. Twelve major international stock indices have been investigated. Error diagram tests show that this new indicator has strong predictive power for financial extremes, both peaks and troughs. By varying the parameters used to construct the error diagram, we show the predictive power is very robust. The new indicator has a better performance than the LPPL pattern recognition indicator.

  3. A method for searching the possible deviations from exponential decay law

    International Nuclear Information System (INIS)

    Tran Dai Nghiep; Vu Hoang Lam; Tran Vien Ha

    1993-01-01

    A continuous kinetic function approach is proposed for analyzing the experimental decay curves. In the case of purely exponential behaviour, the values of kinetic function are the same at different ages of the investigated radionuclide. The deviation from main decay curve could be found by a comparison of experimental kinetic function values with those obtained in purely exponential case. (author). 12 refs

  4. Growth curve models and statistical diagnostics

    CERN Document Server

    Pan, Jian-Xin

    2002-01-01

    Growth-curve models are generalized multivariate analysis-of-variance models. These models are especially useful for investigating growth problems on short times in economics, biology, medical research, and epidemiology. This book systematically introduces the theory of the GCM with particular emphasis on their multivariate statistical diagnostics, which are based mainly on recent developments made by the authors and their collaborators. The authors provide complete proofs of theorems as well as practical data sets and MATLAB code.

  5. Growth Curve Models and Applications : Indian Statistical Institute

    CERN Document Server

    2017-01-01

    Growth curve models in longitudinal studies are widely used to model population size, body height, biomass, fungal growth, and other variables in the biological sciences, but these statistical methods for modeling growth curves and analyzing longitudinal data also extend to general statistics, economics, public health, demographics, epidemiology, SQC, sociology, nano-biotechnology, fluid mechanics, and other applied areas.   There is no one-size-fits-all approach to growth measurement. The selected papers in this volume build on presentations from the GCM workshop held at the Indian Statistical Institute, Giridih, on March 28-29, 2016. They represent recent trends in GCM research on different subject areas, both theoretical and applied. This book includes tools and possibilities for further work through new techniques and modification of existing ones. The volume includes original studies, theoretical findings and case studies from a wide range of app lied work, and these contributions have been externally r...

  6. Modeling the pre-industrial roots of modern super-exponential population growth.

    Science.gov (United States)

    Stutz, Aaron Jonas

    2014-01-01

    To Malthus, rapid human population growth-so evident in 18th Century Europe-was obviously unsustainable. In his Essay on the Principle of Population, Malthus cogently argued that environmental and socioeconomic constraints on population rise were inevitable. Yet, he penned his essay on the eve of the global census size reaching one billion, as nearly two centuries of super-exponential increase were taking off. Introducing a novel extension of J. E. Cohen's hallmark coupled difference equation model of human population dynamics and carrying capacity, this article examines just how elastic population growth limits may be in response to demographic change. The revised model involves a simple formalization of how consumption costs influence carrying capacity elasticity over time. Recognizing that complex social resource-extraction networks support ongoing consumption-based investment in family formation and intergenerational resource transfers, it is important to consider how consumption has impacted the human environment and demography--especially as global population has become very large. Sensitivity analysis of the consumption-cost model's fit to historical population estimates, modern census data, and 21st Century demographic projections supports a critical conclusion. The recent population explosion was systemically determined by long-term, distinctly pre-industrial cultural evolution. It is suggested that modern globalizing transitions in technology, susceptibility to infectious disease, information flows and accumulation, and economic complexity were endogenous products of much earlier biocultural evolution of family formation's embeddedness in larger, hierarchically self-organizing cultural systems, which could potentially support high population elasticity of carrying capacity. Modern super-exponential population growth cannot be considered separately from long-term change in the multi-scalar political economy that connects family formation and

  7. Curve-of-growth analysis of M-type giants. beta. and. beta. Peg

    Energy Technology Data Exchange (ETDEWEB)

    Hanni, L.; Kipper, M.

    1975-01-01

    The curve-of-growth analysis is carried out with high-dispersion spectrograms of the region lambda lambda 5050--6150 for two M-type stars ..beta.. And (MOIII) and ..beta.. Peg (M2II-III) by using the newest oscillator strengths available. It has been found that the form of our empirical curve of growth is consistent with that of the theoretical curve by Wrubel. By making use of the data derived from the curve-of-growth analyses, atmospheric parameters such as THETA/sub ex/, rho/sub e/, ..nu../sub t/ and the abundances of the elements have been determined.

  8. Exponential Decay Nonlinear Regression Analysis of Patient Survival Curves: Preliminary Assessment in Non-Small Cell Lung Cancer

    Science.gov (United States)

    Stewart, David J.; Behrens, Carmen; Roth, Jack; Wistuba, Ignacio I.

    2010-01-01

    Background For processes that follow first order kinetics, exponential decay nonlinear regression analysis (EDNRA) may delineate curve characteristics and suggest processes affecting curve shape. We conducted a preliminary feasibility assessment of EDNRA of patient survival curves. Methods EDNRA was performed on Kaplan-Meier overall survival (OS) and time-to-relapse (TTR) curves for 323 patients with resected NSCLC and on OS and progression-free survival (PFS) curves from selected publications. Results and Conclusions In our resected patients, TTR curves were triphasic with a “cured” fraction of 60.7% (half-life [t1/2] >100,000 months), a rapidly-relapsing group (7.4%, t1/2=5.9 months) and a slowly-relapsing group (31.9%, t1/2=23.6 months). OS was uniphasic (t1/2=74.3 months), suggesting an impact of co-morbidities; hence, tumor molecular characteristics would more likely predict TTR than OS. Of 172 published curves analyzed, 72 (42%) were uniphasic, 92 (53%) were biphasic, 8 (5%) were triphasic. With first-line chemotherapy in advanced NSCLC, 87.5% of curves from 2-3 drug regimens were uniphasic vs only 20% of those with best supportive care or 1 drug (p<0.001). 54% of curves from 2-3 drug regimens had convex rapid-decay phases vs 0% with fewer agents (p<0.001). Curve convexities suggest that discontinuing chemotherapy after 3-6 cycles “synchronizes” patient progression and death. With postoperative adjuvant chemotherapy, the PFS rapid-decay phase accounted for a smaller proportion of the population than in controls (p=0.02) with no significant difference in rapid-decay t1/2, suggesting adjuvant chemotherapy may move a subpopulation of patients with sensitive tumors from the relapsing group to the cured group, with minimal impact on time to relapse for a larger group of patients with resistant tumors. In untreated patients, the proportion of patients in the rapid-decay phase increased (p=0.04) while rapid-decay t1/2 decreased (p=0.0004) with increasing

  9. Developmental trajectories of adolescent popularity: a growth curve modelling analysis.

    Science.gov (United States)

    Cillessen, Antonius H N; Borch, Casey

    2006-12-01

    Growth curve modelling was used to examine developmental trajectories of sociometric and perceived popularity across eight years in adolescence, and the effects of gender, overt aggression, and relational aggression on these trajectories. Participants were 303 initially popular students (167 girls, 136 boys) for whom sociometric data were available in Grades 5-12. The popularity and aggression constructs were stable but non-overlapping developmental dimensions. Growth curve models were run with SAS MIXED in the framework of the multilevel model for change [Singer, J. D., & Willett, J. B. (2003). Applied longitudinal data analysis. Oxford, UK: Oxford University Press]. Sociometric popularity showed a linear change trajectory; perceived popularity showed nonlinear change. Overt aggression predicted low sociometric popularity but an increase in perceived popularity in the second half of the study. Relational aggression predicted a decrease in sociometric popularity, especially for girls, and continued high-perceived popularity for both genders. The effect of relational aggression on perceived popularity was the strongest around the transition from middle to high school. The importance of growth curve models for understanding adolescent social development was discussed, as well as specific issues and challenges of growth curve analyses with sociometric data.

  10. Modelling growth curves of Nigerian indigenous normal feather ...

    African Journals Online (AJOL)

    This study was conducted to predict the growth curve parameters using Bayesian Gompertz and logistic models and also to compare the two growth function in describing the body weight changes across age in Nigerian indigenous normal feather chicken. Each chick was wing-tagged at day old and body weights were ...

  11. Modeling error distributions of growth curve models through Bayesian methods.

    Science.gov (United States)

    Zhang, Zhiyong

    2016-06-01

    Growth curve models are widely used in social and behavioral sciences. However, typical growth curve models often assume that the errors are normally distributed although non-normal data may be even more common than normal data. In order to avoid possible statistical inference problems in blindly assuming normality, a general Bayesian framework is proposed to flexibly model normal and non-normal data through the explicit specification of the error distributions. A simulation study shows when the distribution of the error is correctly specified, one can avoid the loss in the efficiency of standard error estimates. A real example on the analysis of mathematical ability growth data from the Early Childhood Longitudinal Study, Kindergarten Class of 1998-99 is used to show the application of the proposed methods. Instructions and code on how to conduct growth curve analysis with both normal and non-normal error distributions using the the MCMC procedure of SAS are provided.

  12. The Cultural Divide: Exponential Growth in Classical 2D and Metabolic Equilibrium in 3D Environments

    DEFF Research Database (Denmark)

    Wrzesinski, Krzysztof; Rogowska-Wrzesinska, Adelina; Kanlaya, Rattiyaporn

    2014-01-01

    Introduction: Cellular metabolism can be considered to have two extremes: one is characterized by exponential growth (in 2D cultures) and the other by a dynamic equilibrium (in 3D cultures). We have analyzed the proteome and cellular architecture at these two extremes and found that they are dram......Introduction: Cellular metabolism can be considered to have two extremes: one is characterized by exponential growth (in 2D cultures) and the other by a dynamic equilibrium (in 3D cultures). We have analyzed the proteome and cellular architecture at these two extremes and found...... that they are dramatically different. Results: Structurally, actin organization is changed, microtubules are increased and keratins 8 and 18 decreased. Metabolically, glycolysis, fatty acid metabolism and the pentose phosphate shunt are increased while TCA cycle and oxidative phosphorylation is unchanged. Enzymes involved...

  13. TRANSMUTED EXPONENTIATED EXPONENTIAL DISTRIBUTION

    OpenAIRE

    MEROVCI, FATON

    2013-01-01

    In this article, we generalize the exponentiated exponential distribution using the quadratic rank transmutation map studied by Shaw etal. [6] to develop a transmuted exponentiated exponential distribution. Theproperties of this distribution are derived and the estimation of the model parameters is discussed. An application to real data set are finally presented forillustration

  14. Blowing-up Semilinear Wave Equation with Exponential ...

    Indian Academy of Sciences (India)

    Blowing-up Semilinear Wave Equation with Exponential Nonlinearity in Two Space ... We investigate the initial value problem for some semi-linear wave equation in two space dimensions with exponential nonlinearity growth. ... Current Issue

  15. Exponential growth of dental schools in Chile: effects on academic, economic and workforce issues.

    Science.gov (United States)

    Cartes-Velásquez, Ricardo Andrés

    2013-01-01

    In the last 30 years, Chile has undergone noteworthy economic development and an exponential growth in the access of its population to higher education. The aim of this paper was to review the changes in academic, economic and workforce issues that occurred as a consequence of the growth in supply of undergraduate dental vacancies between 1997 and 2011. Data collected from the Consejo de Educación Superior - CES, Comisión Nacional de Acreditación - CNA, and Instituto Nacional de Estadísticas de Chile - INE included these variables: number of dental schools, school type (private or traditional, see explanation below), city where the school is located, entry vacancies, total student enrollment, admission scores, percentile rank of dentistry as a university career, tuition fees, accreditation status, and number of inhabitants. There was an exponential increase in dental schools in Chile (5 to 34) that occurred in association with the rise in tuition fees (US$ 3900 to US$ 9800), a deterioration in the academic level of dental students (650 to 550 points in admission scores) and a predicted 77.5% oversupply of dentists by 2025, according to WHO criteria. The exponential increase in dental schools in Chile brought about negative consequences, such as increasing career costs, deterioration in the academic level of dental students, and an oversupply of dentists, associated with lower incomes and possibly leading to unemployment. Additional research should be conducted to determine whether an increase in the number of dentists can improve the population's access to dental care and reduce the oral disease burden.

  16. Exponential growth of dental schools in Chile: effects on academic, economic and workforce issues

    Directory of Open Access Journals (Sweden)

    Ricardo Andres Cartes-Velasquez

    2013-12-01

    Full Text Available In the last 30 years, Chile has undergone noteworthy economic development and an exponential growth in the access of its population to higher education. The aim of this paper was to review the changes in academic, economic and workforce issues that occurred as a consequence of the growth in supply of undergraduate dental vacancies between 1997 and 2011. Data collected from the Consejo de Educación Superior - CES, Comisión Nacional de Acreditación - CNA, and Instituto Nacional de Estadísticas de Chile - INE included these variables: number of dental schools, school type (private or traditional, see explanation below, city where the school is located, entry vacancies, total student enrollment, admission scores, percentile rank of dentistry as a university career, tuition fees, accreditation status, and number of inhabitants. There was an exponential increase in dental schools in Chile (5 to 34 that occurred in association with the rise in tuition fees (US$ 3900 to US$ 9800, a deterioration in the academic level of dental students (650 to 550 points in admission scores and a predicted 77.5% oversupply of dentists by 2025, according to WHO criteria. The exponential increase in dental schools in Chile brought about negative consequences, such as increasing career costs, deterioration in the academic level of dental students, and an oversupply of dentists, associated with lower incomes and possibly leading to unemployment. Additional research should be conducted to determine whether an increase in the number of dentists can improve the population's access to dental care and reduce the oral disease burden.

  17. Exponential energy growth due to slow parameter oscillations in quantum mechanical systems.

    Science.gov (United States)

    Turaev, Dmitry

    2016-05-01

    It is shown that a periodic emergence and destruction of an additional quantum number leads to an exponential growth of energy of a quantum mechanical system subjected to a slow periodic variation of parameters. The main example is given by systems (e.g., quantum billiards and quantum graphs) with periodically divided configuration space. In special cases, the process can also lead to a long period of cooling that precedes the acceleration, and to the desertion of the states with a particular value of the quantum number.

  18. Exponential and Logarithmic Functions

    OpenAIRE

    Todorova, Tamara

    2010-01-01

    Exponential functions find applications in economics in relation to growth and economic dynamics. In these fields, quite often the choice variable is time and economists are trying to determine the best timing for certain economic activities to take place. An exponential function is one in which the independent variable appears in the exponent. Very often that exponent is time. In highly mathematical courses, it is a truism that students learn by doing, not by reading. Tamara Todorova’s Pr...

  19. Residual Structures in Latent Growth Curve Modeling

    Science.gov (United States)

    Grimm, Kevin J.; Widaman, Keith F.

    2010-01-01

    Several alternatives are available for specifying the residual structure in latent growth curve modeling. Two specifications involve uncorrelated residuals and represent the most commonly used residual structures. The first, building on repeated measures analysis of variance and common specifications in multilevel models, forces residual variances…

  20. Distortion-product otoacoustic emission growth curves in neonates

    Directory of Open Access Journals (Sweden)

    Tania Alves Barbosa

    2014-12-01

    Full Text Available Background: The recording of otoacoustic emissions (OAE enabled us to prove that the cochlea is able not only to receive sounds but also to produce acoustic energy. Through the use of distortion-product otoacoustic emission measurements, the growth of the response was seen according to the intensity of the sound stimulus presented (growth curve. Objective: to determine the thresholds for the emergence of distortion-product otoacoustic emissions (DPOAE on frequencies of 2000 and 4000 Hz with a stimulus varying from 20 to 65dB SPL, and to establish the slope values obtained in the growth curves. Methods: 39 neonates aged 5 to 28 days without risk indicators of hearing loss were studied. The DPOAE growth curves were obtained on the frequencies from 2000 Hz and 4000 Hz with a level of intensity ranging from 20 to 65dB SPL divided into two paradigms (20 to 40dB SPL and 40-65dB SPL. Results: there was a statistically significant difference in the thresholds for the emergence of DPOAE depending on the criteria used. The thresholds were on average higher at 4000 Hz than 2000 Hz and the slope was higher on average at 2000 Hz than 4000 Hz, although not statistically significant in either case. Conclusion: the thresholds were on average 30dB SPL at 2000Hz and 35dB SPL at 4000Hz. The slope values varied between 3 and 4 on average, reaching 15 in some cases.

  1. Dissolution glow curve in LLD

    International Nuclear Information System (INIS)

    Haverkamp, U.; Wiezorek, C.; Poetter, R.

    1990-01-01

    Lyoluminescence dosimetry is based upon light emission during dissolution of previously irradiated dosimetric materials. The lyoluminescence signal is expressed in the dissolution glow curve. These curves begin, depending on the dissolution system, with a high peak followed by an exponentially decreasing intensity. System parameters that influence the graph of the dissolution glow curve, are, for example, injection speed, temperature and pH value of the solution and the design of the dissolution cell. The initial peak does not significantly correlate with the absorbed dose, it is mainly an effect of the injection. The decay of the curve consists of two exponential components: one fast and one slow. The components depend on the absorbed dose and the dosimetric materials used. In particular, the slow component correlates with the absorbed dose. In contrast to the fast component the argument of the exponential function of the slow component is independent of the dosimetric materials investigated: trehalose, glucose and mannitol. The maximum value, following the peak of the curve, and the integral light output are a measure of the absorbed dose. The reason for the different light outputs of various dosimetric materials after irradiation with the same dose is the differing solubility. The character of the dissolution glow curves is the same following irradiation with photons, electrons or neutrons. (author)

  2. Modeling the Lag Period and Exponential Growth of Listeria monocytogenes under Conditions of Fluctuating Temperature and Water Activity Values▿

    Science.gov (United States)

    Muñoz-Cuevas, Marina; Fernández, Pablo S.; George, Susan; Pin, Carmen

    2010-01-01

    The dynamic model for the growth of a bacterial population described by Baranyi and Roberts (J. Baranyi and T. A. Roberts, Int. J. Food Microbiol. 23:277-294, 1994) was applied to model the lag period and exponential growth of Listeria monocytogenes under conditions of fluctuating temperature and water activity (aw) values. To model the duration of the lag phase, the dependence of the parameter h0, which quantifies the amount of work done during the lag period, on the previous and current environmental conditions was determined experimentally. This parameter depended not only on the magnitude of the change between the previous and current environmental conditions but also on the current growth conditions. In an exponentially growing population, any change in the environment requiring a certain amount of work to adapt to the new conditions initiated a lag period that lasted until that work was finished. Observations for several scenarios in which exponential growth was halted by a sudden change in the temperature and/or aw were in good agreement with predictions. When a population already in a lag period was subjected to environmental fluctuations, the system was reset with a new lag phase. The work to be done during the new lag phase was estimated to be the workload due to the environmental change plus the unfinished workload from the uncompleted previous lag phase. PMID:20208022

  3. Modeling the lag period and exponential growth of Listeria monocytogenes under conditions of fluctuating temperature and water activity values.

    Science.gov (United States)

    Muñoz-Cuevas, Marina; Fernández, Pablo S; George, Susan; Pin, Carmen

    2010-05-01

    The dynamic model for the growth of a bacterial population described by Baranyi and Roberts (J. Baranyi and T. A. Roberts, Int. J. Food Microbiol. 23:277-294, 1994) was applied to model the lag period and exponential growth of Listeria monocytogenes under conditions of fluctuating temperature and water activity (a(w)) values. To model the duration of the lag phase, the dependence of the parameter h(0), which quantifies the amount of work done during the lag period, on the previous and current environmental conditions was determined experimentally. This parameter depended not only on the magnitude of the change between the previous and current environmental conditions but also on the current growth conditions. In an exponentially growing population, any change in the environment requiring a certain amount of work to adapt to the new conditions initiated a lag period that lasted until that work was finished. Observations for several scenarios in which exponential growth was halted by a sudden change in the temperature and/or a(w) were in good agreement with predictions. When a population already in a lag period was subjected to environmental fluctuations, the system was reset with a new lag phase. The work to be done during the new lag phase was estimated to be the workload due to the environmental change plus the unfinished workload from the uncompleted previous lag phase.

  4. Review of "Going Exponential: Growing the Charter School Sector's Best"

    Science.gov (United States)

    Garcia, David

    2011-01-01

    This Progressive Policy Institute report argues that charter schools should be expanded rapidly and exponentially. Citing exponential growth organizations, such as Starbucks and Apple, as well as the rapid growth of molds, viruses and cancers, the report advocates for similar growth models for charter schools. However, there is no explanation of…

  5. Investigation of Mediational Processes Using Parallel Process Latent Growth Curve Modeling

    Science.gov (United States)

    Cheong, JeeWon; MacKinnon, David P.; Khoo, Siek Toon

    2010-01-01

    This study investigated a method to evaluate mediational processes using latent growth curve modeling. The mediator and the outcome measured across multiple time points were viewed as 2 separate parallel processes. The mediational process was defined as the independent variable influencing the growth of the mediator, which, in turn, affected the growth of the outcome. To illustrate modeling procedures, empirical data from a longitudinal drug prevention program, Adolescents Training and Learning to Avoid Steroids, were used. The program effects on the growth of the mediator and the growth of the outcome were examined first in a 2-group structural equation model. The mediational process was then modeled and tested in a parallel process latent growth curve model by relating the prevention program condition, the growth rate factor of the mediator, and the growth rate factor of the outcome. PMID:20157639

  6. Elliptic curves for applications (Tutorial)

    NARCIS (Netherlands)

    Lange, T.; Bernstein, D.J.; Chatterjee, S.

    2011-01-01

    More than 25 years ago, elliptic curves over finite fields were suggested as a group in which the Discrete Logarithm Problem (DLP) can be hard. Since then many researchers have scrutinized the security of the DLP on elliptic curves with the result that for suitably chosen curves only exponential

  7. Supplementary Material for: Growth curve registration for evaluating salinity tolerance in barley

    KAUST Repository

    Meng, Rui

    2017-01-01

    Abstract Background Smarthouses capable of non-destructive, high-throughput plant phenotyping collect large amounts of data that can be used to understand plant growth and productivity in extreme environments. The challenge is to apply the statistical tool that best analyzes the data to study plant traits, such as salinity tolerance, or plant-growth-related traits. Results We derive family-wise salinity sensitivity (FSS) growth curves and use registration techniques to summarize growth patterns of HEB-25 barley families and the commercial variety, Navigator. We account for the spatial variation in smarthouse microclimates and in temporal variation across phenotyping runs using a functional ANOVA model to derive corrected FSS curves. From FSS, we derive corrected values for family-wise salinity tolerance, which are strongly negatively correlated with Na but not significantly with K, indicating that Na content is an important factor affecting salinity tolerance in these families, at least for plants of this age and grown in these conditions. Conclusions Our family-wise methodology is suitable for analyzing the growth curves of a large number of plants from multiple families. The corrected curves accurately account for the spatial and temporal variations among plants that are inherent to high-throughput experiments.

  8. A method for nonlinear exponential regression analysis

    Science.gov (United States)

    Junkin, B. G.

    1971-01-01

    A computer-oriented technique is presented for performing a nonlinear exponential regression analysis on decay-type experimental data. The technique involves the least squares procedure wherein the nonlinear problem is linearized by expansion in a Taylor series. A linear curve fitting procedure for determining the initial nominal estimates for the unknown exponential model parameters is included as an integral part of the technique. A correction matrix was derived and then applied to the nominal estimate to produce an improved set of model parameters. The solution cycle is repeated until some predetermined criterion is satisfied.

  9. Growth curves and the international standard: How children's growth reflects challenging conditions in rural Timor-Leste.

    Science.gov (United States)

    Spencer, Phoebe R; Sanders, Katherine A; Judge, Debra S

    2018-02-01

    Population-specific growth references are important in understanding local growth variation, especially in developing countries where child growth is poor and the need for effective health interventions is high. In this article, we use mixed longitudinal data to calculate the first growth curves for rural East Timorese children to identify where, during development, deviation from the international standards occurs. Over an eight-year period, 1,245 children from two ecologically distinct rural areas of Timor-Leste were measured a total of 4,904 times. We compared growth to the World Health Organization (WHO) standards using z-scores, and modeled height and weight velocity using the SuperImposition by Translation And Rotation (SITAR) method. Using the Generalized Additive Model for Location, Scale and Shape (GAMLSS) method, we created the first growth curves for rural Timorese children for height, weight and body mass index (BMI). Relative to the WHO standards, children show early-life growth faltering, and stunting throughout childhood and adolescence. The median height and weight for this population tracks below the WHO fifth centile. Males have poorer growth than females in both z-BMI (p = .001) and z-height-for-age (p = .018) and, unlike females, continue to grow into adulthood. This is the most comprehensive investigation to date of rural Timorese children's growth, and the growth curves created may potentially be used to identify future secular trends in growth as the country develops. We show significant deviation from the international standard that becomes most pronounced at adolescence, similar to the growth of other Asian populations. Males and females show different growth responses to challenging conditions in this population. © 2017 Wiley Periodicals, Inc.

  10. [Reference curves for assessing the physical growth of male Wistar rats].

    Science.gov (United States)

    Cossio-Bolaños, Marco; Gómez Campos, Rossana; Vargas Vitoria, Rodrigo; Hochmuller Fogaça, Rosalvo Tadeu; de Arruda, Miguel

    2013-11-01

    Wistar rats are one of the most popular strains routinely used for research in the laboratory to serve as an important research tool, so it requires strict control of variables such as age, sex and body weight, and Thus to extrapolate the results to the human model. To develop reference curves for assessing the physical growth of male Wistar rats according to chronological age and somatic maturation from a non-invasive. The subjects studied were 731 male Wistar rats transversely. We assessed age, body weight and body surface. LMS method was used to construct percentile curves based on weight and somatic maturation. The proposed physical growth curves are used to track the physical growth and nutritional status diagnosis of male Wistar rats. Budgets by cutting points are: P3, P10, P25, P50, P75, P90 and P97. The results suggest that scientists from different areas can use such references, in order to extrapolate somatic growth phases of the laboratory rat and the human model is a non-invasive alternative to assess growth and nutritional status. Copyright AULA MEDICA EDICIONES 2013. Published by AULA MEDICA. All rights reserved.

  11. Short communication Estimation of growth curve parameters in ...

    African Journals Online (AJOL)

    ikeskin

    The shape of growth curves has been reported to vary according to the species of .... a,b,c The means within columns with different superscripts are significantly .... J. Anim. Sci. 84, 2642-2654. The South African Journal of Animal Science is ...

  12. An Approach of Estimating Individual Growth Curves for Young Thoroughbred Horses Based on Their Birthdays

    Science.gov (United States)

    ONODA, Tomoaki; YAMAMOTO, Ryuta; SAWAMURA, Kyohei; MURASE, Harutaka; NAMBO, Yasuo; INOUE, Yoshinobu; MATSUI, Akira; MIYAKE, Takeshi; HIRAI, Nobuhiro

    2014-01-01

    ABSTRACT We propose an approach of estimating individual growth curves based on the birthday information of Japanese Thoroughbred horses, with considerations of the seasonal compensatory growth that is a typical characteristic of seasonal breeding animals. The compensatory growth patterns appear during only the winter and spring seasons in the life of growing horses, and the meeting point between winter and spring depends on the birthday of each horse. We previously developed new growth curve equations for Japanese Thoroughbreds adjusting for compensatory growth. Based on the equations, a parameter denoting the birthday information was added for the modeling of the individual growth curves for each horse by shifting the meeting points in the compensatory growth periods. A total of 5,594 and 5,680 body weight and age measurements of Thoroughbred colts and fillies, respectively, and 3,770 withers height and age measurements of both sexes were used in the analyses. The results of predicted error difference and Akaike Information Criterion showed that the individual growth curves using birthday information better fit to the body weight and withers height data than not using them. The individual growth curve for each horse would be a useful tool for the feeding managements of young Japanese Thoroughbreds in compensatory growth periods. PMID:25013356

  13. Growth Curve and Structural Equation Modeling : Topics from the Indian Statistical Institute

    CERN Document Server

    2015-01-01

    This book describes some recent trends in GCM research on different subject areas, both theoretical and applied. This includes tools and possibilities for further work through new techniques and modification of existing ones. A growth curve is an empirical model of the evolution of a quantity over time. Growth curves in longitudinal studies are used in disciplines including biology, statistics, population studies, economics, biological sciences, sociology, nano-biotechnology, and fluid mechanics. The volume includes original studies, theoretical findings and case studies from a wide range of applied work. This volume builds on presentations from a GCM workshop held at the Indian Statistical Institute, Giridih, January 18-19, 2014. This book follows the volume Advances in Growth Curve Models, published by Springer in 2013. The results have meaningful application in health care, prediction of crop yield, child nutrition, poverty measurements, estimation of growth rate, and other research areas.

  14. ECONOMIC GROWTH AND AIR POLLUTION IN THECZECHREPUBLIC: DECOUPLING CURVES

    Directory of Open Access Journals (Sweden)

    Petr Šauer

    2012-07-01

    Full Text Available The decoupling curve, together with the Environmental Kuznets Curve, has beenrecognized as one of the important indicators showing relations betweeneconomic growth and environmental degradation/pollution. Many boththeoreticaland empirical studies have been published on it. Our paper brings models whichinvestigate relations between the economic growth per capita and selectedindicators of air pollution in theCzechRepublic. The analysis tried to go beforethe year 1990, despite the difficulties when dealing with different macroeconomicindicators published during the socialist period and those introduced after thetransition to a market economy. The results might be somehow surprising forthose dealing only with data generated after the year 1990: it is possible todiscover the turning points for some of the airborne pollutants already in the1980s.

  15. Science in an Exponential World

    Science.gov (United States)

    Szalay, Alexander

    The amount of scientific information is doubling every year. This exponential growth is fundamentally changing every aspect of the scientific process - the collection, analysis and dissemination of scientific information. Our traditional paradigm for scientific publishing assumes a linear world, where the number of journals and articles remains approximately constant. The talk presents the challenges of this new paradigm and shows examples of how some disciplines are trying to cope with the data avalanche. In astronomy, the Virtual Observatory is emerging as a way to do astronomy in the 21st century. Other disciplines are also in the process of creating their own Virtual Observatories, on every imaginable scale of the physical world. We will discuss how long this exponential growth can continue.

  16. The Trypanosoma cruzi nucleolus: a morphometrical analysis of cultured epimastigotes in the exponential and stationary phases.

    Science.gov (United States)

    Nepomuceno-Mejía, Tomás; Lara-Martínez, Reyna; Cevallos, Ana María; López-Villaseñor, Imelda; Jiménez-García, Luis Felipe; Hernández, Roberto

    2010-12-01

    Our group is interested in rRNA and ribosome biogenesis in the parasitic protozoan Trypanosoma cruzi. Epimastigotes represent an extracellular replicative stage of T. cruzi and can be cultured in axenic media. The growth curve of epimastigotes allows assessment of potential differences in the nucleoli of cells undergoing growth-rate transitions. To establish cellular parameters for studying ribosome biogenesis in T. cruzi, a morphometric analysis of the nucleoli of cultured cells in the exponential and stationary phases was conducted. Electron micrograph-based measurements of nuclear sections from independent cells demonstrated that the nucleolar area is over twofold higher in exponentially growing cells, as compared with epimastigotes in the stationary phase. The granular component of the nucleoli of actively growing cells was the main structural element. Cycloheximide moderately reduced the apparent size of the nucleoli without an apparent disruption of their architecture. Our results provide a firm basis for the establishment of an experimental model to study the organization of the nucleolus during the growth and development of T. cruzi. © 2010 Federation of European Microbiological Societies Published by Blackwell Publishing Ltd. All rights reserved.

  17. Revisiting the environmental Kuznets curve hypothesis in a tourism development context.

    Science.gov (United States)

    de Vita, Glauco; Katircioglu, Salih; Altinay, Levent; Fethi, Sami; Mercan, Mehmet

    2015-11-01

    This study investigates empirically an extended version of the Environmental Kuznets Curve model that controls for tourism development. We find that international tourist arrivals into Turkey alongside income, squared income and energy consumption, cointegrate with CO2 emissions. Tourist arrivals, growth, and energy consumption exert a positive and significant impact on CO2 emissions in the long-run. Our results provide empirical support to EKC hypothesis showing that at exponential levels of growth, CO2 emissions decline. The findings suggest that despite the environmental degradation stemming from tourism development, policies aimed at environmental protection should not be pursued at the expense of tourism-led growth.

  18. Dynamic Regulation of a Cell Adhesion Protein Complex Including CADM1 by Combinatorial Analysis of FRAP with Exponential Curve-Fitting

    Science.gov (United States)

    Sakurai-Yageta, Mika; Maruyama, Tomoko; Suzuki, Takashi; Ichikawa, Kazuhisa; Murakami, Yoshinori

    2015-01-01

    Protein components of cell adhesion machinery show continuous renewal even in the static state of epithelial cells and participate in the formation and maintenance of normal epithelial architecture and tumor suppression. CADM1 is a tumor suppressor belonging to the immunoglobulin superfamily of cell adhesion molecule and forms a cell adhesion complex with an actin-binding protein, 4.1B, and a scaffold protein, MPP3, in the cytoplasm. Here, we investigate dynamic regulation of the CADM1-4.1B-MPP3 complex in mature cell adhesion by fluorescence recovery after photobleaching (FRAP) analysis. Traditional FRAP analysis were performed for relatively short period of around 10min. Here, thanks to recent advances in the sensitive laser detector systems, we examine FRAP of CADM1 complex for longer period of 60 min and analyze the recovery with exponential curve-fitting to distinguish the fractions with different diffusion constants. This approach reveals that the fluorescence recovery of CADM1 is fitted to a single exponential function with a time constant (τ) of approximately 16 min, whereas 4.1B and MPP3 are fitted to a double exponential function with two τs of approximately 40-60 sec and 16 min. The longer τ is similar to that of CADM1, suggesting that 4.1B and MPP3 have two distinct fractions, one forming a complex with CADM1 and the other present as a free pool. Fluorescence loss in photobleaching analysis supports the presence of a free pool of these proteins near the plasma membrane. Furthermore, double exponential fitting makes it possible to estimate the ratio of 4.1B and MPP3 present as a free pool and as a complex with CADM1 as approximately 3:2 and 3:1, respectively. Our analyses reveal a central role of CADM1 in stabilizing the complex with 4.1B and MPP3 and provide insight in the dynamics of adhesion complex formation. PMID:25780926

  19. Analytical investigations of thermoluminescence glow curve on quartz for luminescence dating

    International Nuclear Information System (INIS)

    Kim, K.B.; Hong, D.G.

    2015-01-01

    Investigations of bleaching and thermoluminescence (TL) response to radiation dose of quartz are importance in luminescence dating. Although such research has been extensively carried out for various types of quartz, most work was performed on the basis of TL intensity integrated for a particular temperature range on the glow curve, without any peak separation. In this study we investigated bleaching by a blue light stimulation and radiation dose behaviour for separated TL glow peaks of quartz, which are thermally stable, by using the computerized glow curve deconvolution (CGCD) method combined with the T_m–T_s_t_o_p method. The T_m–T_s_t_o_p method indicates that the glow curve of quartz is the superposition of at least seven components (P1–P7) in the temperature range between room temperature and 450 °C. A bleaching experiment for four thermally stable glow peaks (P4–P7) using a blue light stimulation revealed that the bleaching rate of peak P4 exhibits three different exponential decays, whereas the peaks P5, P6 and P7 are bleached with two different exponential decays. After bleaching of 12 h, the TL intensity of peaks P4, P5, P6 and P7 were reduced to approximately 6%, 16%, 26% and 68% of the initial value, respectively. Additionally, in a study of the radiation dose response of the four thermally stable glow peaks, all peaks have a similar pattern, which are well fitted by a single saturating exponential function. - Highlights: • We studied the physical characteristics of the separated TL glow peaks on quartz. • The kinetic parameters of each separated glow peak are evaluated by a CGCD method. • The separated peaks were bleached with two or three exponential decays. • The dose responses for the separated peaks showed a similar growth curve.

  20. Symphysis-fundal height curve in the diagnosis of fetal growth deviations

    Directory of Open Access Journals (Sweden)

    Djacyr Magna Cabral Freire

    2010-12-01

    Full Text Available OBJECTIVE: To validate a new symphysis-fundal curve for screening fetal growth deviations and to compare its performance with the standard curve adopted by the Brazilian Ministry of Health. METHODS: Observational study including a total of 753 low-risk pregnant women with gestational age above 27 weeks between March to October 2006 in the city of João Pessoa, Northeastern Brazil. Symphisys-fundal was measured using a standard technique recommended by the Brazilian Ministry of Health. Estimated fetal weight assessed through ultrasound using the Brazilian fetal weight chart for gestational age was the gold standard. A subsample of 122 women with neonatal weight measurements was taken up to seven days after estimated fetal weight measurements and symphisys-fundal classification was compared with Lubchenco growth reference curve as gold standard. Sensitivity, specificity, positive and negative predictive values were calculated. The McNemar χ2 test was used for comparing sensitivity of both symphisys-fundal curves studied. RESULTS: The sensitivity of the new curve for detecting small for gestational age fetuses was 51.6% while that of the Brazilian Ministry of Health reference curve was significantly lower (12.5%. In the subsample using neonatal weight as gold standard, the sensitivity of the new reference curve was 85.7% while that of the Brazilian Ministry of Health was 42.9% for detecting small for gestational age. CONCLUSIONS: The diagnostic performance of the new curve for detecting small for gestational age fetuses was significantly higher than that of the Brazilian Ministry of Health reference curve.

  1. Late-time acceleration with steep exponential potentials

    Energy Technology Data Exchange (ETDEWEB)

    Shahalam, M. [Zhejiang University of Technology, Institute for Advanced Physics and Mathematics, Hangzhou (China); Yang, Weiqiang [Liaoning Normal University, Department of Physics, Dalian (China); Myrzakulov, R. [Eurasian National University, Department of General and Theoretical Physics, Eurasian International Center for Theoretical Physics, Astana (Kazakhstan); Wang, Anzhong [Zhejiang University of Technology, Institute for Advanced Physics and Mathematics, Hangzhou (China); Baylor University, GCAP-CASPER, Department of Physics, Waco, TX (United States)

    2017-12-15

    In this letter, we study the cosmological dynamics of steeper potential than exponential. Our analysis shows that a simple extension of an exponential potential allows to capture late-time cosmic acceleration and retain the tracker behavior. We also perform statefinder and Om diagnostics to distinguish dark energy models among themselves and with ΛCDM. In addition, to put the observational constraints on the model parameters, we modify the publicly available CosmoMC code and use an integrated data base of baryon acoustic oscillation, latest Type Ia supernova from Joint Light Curves sample and the local Hubble constant value measured by the Hubble Space Telescope. (orig.)

  2. Late-time acceleration with steep exponential potentials

    International Nuclear Information System (INIS)

    Shahalam, M.; Yang, Weiqiang; Myrzakulov, R.; Wang, Anzhong

    2017-01-01

    In this letter, we study the cosmological dynamics of steeper potential than exponential. Our analysis shows that a simple extension of an exponential potential allows to capture late-time cosmic acceleration and retain the tracker behavior. We also perform statefinder and Om diagnostics to distinguish dark energy models among themselves and with ΛCDM. In addition, to put the observational constraints on the model parameters, we modify the publicly available CosmoMC code and use an integrated data base of baryon acoustic oscillation, latest Type Ia supernova from Joint Light Curves sample and the local Hubble constant value measured by the Hubble Space Telescope. (orig.)

  3. Exponential stability in a scalar functional differential equation

    Directory of Open Access Journals (Sweden)

    Pituk Mihály

    2006-01-01

    Full Text Available We establish a criterion for the global exponential stability of the zero solution of the scalar retarded functional differential equation whose linear part generates a monotone semiflow on the phase space with respect to the exponential ordering, and the nonlinearity has at most linear growth.

  4. Predicting Madura cattle growth curve using non-linear model

    Science.gov (United States)

    Widyas, N.; Prastowo, S.; Widi, T. S. M.; Baliarti, E.

    2018-03-01

    Madura cattle is Indonesian native. It is a composite breed that has undergone hundreds of years of selection and domestication to reach nowadays remarkable uniformity. Crossbreeding has reached the isle of Madura and the Madrasin, a cross between Madura cows and Limousine semen emerged. This paper aimed to compare the growth curve between Madrasin and one type of pure Madura cows, the common Madura cattle (Madura) using non-linear models. Madura cattles are kept traditionally thus reliable records are hardly available. Data were collected from small holder farmers in Madura. Cows from different age classes (5years) were observed, and body measurements (chest girth, body length and wither height) were taken. In total 63 Madura and 120 Madrasin records obtained. Linear model was built with cattle sub-populations and age as explanatory variables. Body weights were estimated based on the chest girth. Growth curves were built using logistic regression. Results showed that within the same age, Madrasin has significantly larger body compared to Madura (plogistic models fit better for Madura and Madrasin cattle data; with the estimated MSE for these models were 39.09 and 759.28 with prediction accuracy of 99 and 92% for Madura and Madrasin, respectively. Prediction of growth curve using logistic regression model performed well in both types of Madura cattle. However, attempts to administer accurate data on Madura cattle are necessary to better characterize and study these cattle.

  5. Exponential-Polynomial Families and the Term Structure of Interest Rates

    OpenAIRE

    Filipovic, Damir

    2000-01-01

    Exponential-polynomial families like the Nelson-Siegel or Svensson family are widely used to estimate the current forward rate curve. We investigate whether these methods go well with inter-temporal modelling. We characterize the consistent Ito processes which have the property to provide an arbitrage free interest rate model when representing the parameters of some bounded exponential-polynomial type function. This includes in particular diffusion processes. We show that there is a strong li...

  6. Non-exponential growth of Mycobacterium leprae Thai-53 strain cultured in vitro.

    Science.gov (United States)

    Amako, Kazunobu; Iida, Ken-Ichiro; Saito, Mitsumasa; Ogura, Yoshitoshi; Hayashi, Tetsuya; Yoshida, Shin-Ichi

    2016-12-01

    In this study, attempts were made to culture this bacterium in media supplemented with a variety of biological materials to determine why cultivation of Mycobacterium leprae in vitro has not this far been successful. A slight increase in the number of cells in medium supplemented with human blood plasma and an extract of nude mouse tissue as observed after more than 3 months of cultivation at 30 °C. To ascertain whether this increase was real growth, the growth was analyzed by droplet digital PCR, which showed a slow increase in the copy number of cell-associated DNA and the release of a large amount of DNA into the culture medium from bacterial cells during cultivation. These results were supported by electron microscopic examination of M. leprae in infected mouse tissues, which showed that most of the replicated bacteria had degenerated and only a few cells survived. Based on these results, it was postulated that many of the replicated cells degenerate during M. leprae growth and that only a few cells remain to participate in the next growth stage. This means that, unlike other cultivable bacteria, the growth of M. leprae is not exponential and the number of cells therefore increase extremely slowly. Thus, accurate judging of the success of M. leprae cultivation requires observation of growth over a long period of time and careful measurement of the increase in number of viable cells. © 2016 The Authors. Microbiology and Immunology published by The Societies and John Wiley & Sons Australia, Ltd.

  7. The Biasing Effects of Unmodeled ARMA Time Series Processes on Latent Growth Curve Model Estimates

    Science.gov (United States)

    Sivo, Stephen; Fan, Xitao; Witta, Lea

    2005-01-01

    The purpose of this study was to evaluate the robustness of estimated growth curve models when there is stationary autocorrelation among manifest variable errors. The results suggest that when, in practice, growth curve models are fitted to longitudinal data, alternative rival hypotheses to consider would include growth models that also specify…

  8. Modification by preirradiation growth conditions of the shoulder of the UV fluence-survival curve of Escherichia coli B/r WP2 thy trp and changes in mutagenic response toward tryptophan prototrophy

    International Nuclear Information System (INIS)

    Doudney, C.O.

    1978-01-01

    The distinct three-section UV fluence-mutation frequency response (MFR) curve demonstrated in Escherichia coli strain B/r WP2 thy trp and its uvrA derivative supports the SOS hypothesis and suggests that trp + revertants can arise either from isolated lesions (1DM) plus SOS induction or from two lesions in proximity (2DM). Preirradiation growth on arabinose instead of glucose converted the fluence-survival curve from highly shouldered to exponential but did not affect the three-section MFR curve. Prestarvation of the uvrA + strain for typtophan, which drastically increases the expanse of the shoulder of the survival curve, greatly decreased both 1DM and 2DM. With the uvrA strain the increase in shoulder expanse after typtophan prestarvation was accompanied by greatly increased 2DM but no change in 1DM. Preincubation with chloramphenicol induced an even greater increase in 2DM response than amino acid prestarvation. Nalidixic acid, which prevents DNA accumulation, eliminated the response. (Auth.)

  9. Environmental Kuznets curve and growth source in Iran

    Directory of Open Access Journals (Sweden)

    Asghari Maryam

    2012-01-01

    Full Text Available Recent empirical research has examined the relationship between certain indicators of environmental degradation and income, concluding that in some cases an inverted U-shaped relationship, which has been called an environmental Kuznets curve (EKC, exists between these variables. The source of growth explanation is important for two reasons. First, it demonstrates how the pollution consequences of growth depend on the source of growth. Therefore, the analogy drawn by some in the environmental community between the damaging effects of economic development and those of liberalized trade is, at best, incomplete. Second, the source of growth explanation demonstrates that a strong policy response to income gains is not necessary for pollution to fall with growth. The aim of this paper investigates the role of differences source of growth in environmental quality of Iran. The results show the two growth resources in Iran cause, in the early stages, CO2 emission decreases until turning point but beyond this level of income per capita, economic growth leads to environmental degradation. I find a U relationship between environmental degradation (CO2 emission and economic growth in Iran.

  10. Colombian reference growth curves for height, weight, body mass index and head circumference.

    Science.gov (United States)

    Durán, Paola; Merker, Andrea; Briceño, Germán; Colón, Eugenia; Line, Dionne; Abad, Verónica; Del Toro, Kenny; Chahín, Silvia; Matallana, Audrey Mary; Lema, Adriana; Llano, Mauricio; Céspedes, Jaime; Hagenäs, Lars

    2016-03-01

    Published Growth studies from Latin America are limited to growth references from Argentina and Venezuela. The aim of this study was to construct reference growth curves for height, weight, body mass index (BMI) and head circumference of Colombian children in a format that is useful for following the growth of the individual child and as a tool for public health. Prospective measurements from 27 209 Colombian children from middle and upper socio-economic level families were processed using the generalised additive models for location, scale and shape (GAMLSS). Descriptive statistics for length and height, weight, BMI and head circumference for age are given as raw and smoothed values. Final height was 172.3 cm for boys and 159.4 cm for girls. Weight at 18 years of age was 64.0 kg for boys and 54 kg for girls. Growth curves are presented in a ± 3 SD format using logarithmic axes. The constructed reference growth curves are a start for following secular trends in Colombia and are also in the presented layout an optimal clinical tool for health care. ©2015 Foundation Acta Paediatrica. Published by John Wiley & Sons Ltd.

  11. Common features of a vortex structure in long exponentially shaped Josephson junctions and Josephson junctions with inhomogeneities

    International Nuclear Information System (INIS)

    Boyadjiev, T.L.; Semerdjieva, E.G.; Shukrinov, Yu.M.

    2007-01-01

    We study the vortex structure in three different models of the long Josephson junction: the exponentially shaped Josephson junction and the Josephson junctions with the resistor and the shunt inhomogeneities in the barrier layer. For these three models the critical curves 'critical current-magnetic field' are numerically constructed. We develop the idea of the equivalence of the exponentially shaped Josephson junction and the rectangular junction with the distributed inhomogeneity and demonstrate that at some parameters of the shunt and the resistor inhomogeneities in the ends of the junction the corresponding critical curves are very close to the exponentially shaped one

  12. Modeling Exponential Population Growth

    Science.gov (United States)

    McCormick, Bonnie

    2009-01-01

    The concept of population growth patterns is a key component of understanding evolution by natural selection and population dynamics in ecosystems. The National Science Education Standards (NSES) include standards related to population growth in sections on biological evolution, interdependence of organisms, and science in personal and social…

  13. Using the Yield Curve in Forecasting Output Growth and In‡flation

    DEFF Research Database (Denmark)

    Hillebrand, Eric Tobias; Huang, Huiyu; Lee, Tae-Hwy

    Following Diebold and Li (2006), we use the Nelson-Siegel (NS, 1987) yield curve factors. However the NS yield curve factors are not supervised for a specifi…c forecast target in the sense that the same factors are used for forecasting different variables, e.g., output growth or infl‡ation. We...... analytically and numerically how supervision works. For both CF and CI schemes, principal components (PC) may be used in place of the NS factors. In out-of-sample forecasting of U.S. monthly output growth and infl‡ation, we fi…nd that supervised CF-factor models (CF-NS, CF-PC) are substantially better than...

  14. ECONOMIC GROWTH, TRADE AND ENVIRONMENTAL ISSUES: TESTING ENVIRONMENTAL KUZNETS CURVE

    Directory of Open Access Journals (Sweden)

    Dedi Budiman Hakim

    2013-04-01

    Full Text Available ASEAN experiences a dynamic economic growth due to its liberalised markets. However concerns arise related to environmental issues resulting from the economic activities. It reflects tradeoffs between economic growth driven by trade and foreign direct investment (FDI, and environment. To investigate such a relation the Environmental Kuznets Curve was applied by regressing amount of carbon emission with gross domestic product (GDP, quadratic GDP, trade openness and FDI. The result reveals that amount of carbon emission is linearly and positively correlated with GDP per capita. It is predicted that as ASEAN economies grow, carbon emission increases. Trade openness is also found to contribute to carbon emission. Keywords: Kuznets curve, carbon emission, gross domestic product, trade, foreign direct investment JEL classification number: F15, F18

  15. A comparative study of post-irradiation growth kinetics of spheroids and monolayers

    International Nuclear Information System (INIS)

    Dertinger, J.; Luecke-Huhle, C.

    1975-01-01

    Post-irradiation growth kinetics of γ-irradiated spheroid and monolayer cells in exponential growth phase was investigated by means of dose-response curves based on cell counts after specified time intervals following irradiation. A mathematical model of cell-growth after irradiation was fitted to these curves. The model parameters (related to division delay and growth of non-surviving cells) obtained from this analysis consistently indicated increasing resistance to sub-lethal damage of cells cultured as multicellular spheroids under conditions of increasing three-dimensional contact. In contrast, no indication of an increased radiation-resistance was found with cells cultured on a substratum under a variety of conditions. (author)

  16. Mediation Analysis in a Latent Growth Curve Modeling Framework

    Science.gov (United States)

    von Soest, Tilmann; Hagtvet, Knut A.

    2011-01-01

    This article presents several longitudinal mediation models in the framework of latent growth curve modeling and provides a detailed account of how such models can be constructed. Logical and statistical challenges that might arise when such analyses are conducted are also discussed. Specifically, we discuss how the initial status (intercept) and…

  17. Diffusion-weighted MR imaging of pancreatic cancer: A comparison of mono-exponential, bi-exponential and non-Gaussian kurtosis models.

    Science.gov (United States)

    Kartalis, Nikolaos; Manikis, Georgios C; Loizou, Louiza; Albiin, Nils; Zöllner, Frank G; Del Chiaro, Marco; Marias, Kostas; Papanikolaou, Nikolaos

    2016-01-01

    To compare two Gaussian diffusion-weighted MRI (DWI) models including mono-exponential and bi-exponential, with the non-Gaussian kurtosis model in patients with pancreatic ductal adenocarcinoma. After written informed consent, 15 consecutive patients with pancreatic ductal adenocarcinoma underwent free-breathing DWI (1.5T, b-values: 0, 50, 150, 200, 300, 600 and 1000 s/mm 2 ). Mean values of DWI-derived metrics ADC, D, D*, f, K and D K were calculated from multiple regions of interest in all tumours and non-tumorous parenchyma and compared. Area under the curve was determined for all metrics. Mean ADC and D K showed significant differences between tumours and non-tumorous parenchyma (both P  < 0.001). Area under the curve for ADC, D, D*, f, K, and D K were 0.77, 0.52, 0.53, 0.62, 0.42, and 0.84, respectively. ADC and D K could differentiate tumours from non-tumorous parenchyma with the latter showing a higher diagnostic accuracy. Correction for kurtosis effects has the potential to increase the diagnostic accuracy of DWI in patients with pancreatic ductal adenocarcinoma.

  18. Effects of low dose rate γ-rays on cell proliferation and survival in exponentially growing and plateau phase cultures of normal rat kidney cells

    International Nuclear Information System (INIS)

    Tsuboi, A.

    1982-01-01

    The effects of 60 Co γ-rays on cell clonogenicity and cell proliferation were examined in NRK cells in exponential and plateau growth phases during and after irradiation at various dose rates. The typical dese rate effect for the survival responses was observed between acute irradiation and continuous irradiation at dose rates of 9.6-44 rads/h. Similar dose rate effect for the perturbation of the proliferation was observed in exponentially growing cells during irradiation. Some differences were found in survival when the cells were exposed to γ-rays at 9.6 rads/h or at 13.7 rads/h. The survival curves of exponential phase cells irradiated at these dose rates showed a shape different from that observed in plateau phase cells. Namely, a steady state of survival appeared around an accumulated dose of 1000 rads (dose-rate of 9.6 rads/h) and an accumulated dose of 1500 rads (dose-rate of 13.7 rads/h) in the exponential phase cells, while such a steady state of survival was not detected in plateau phase cells after similar conditions of irradiation. Moreover, the extrapolation number of the survival curve was much larger at the lower dose rate in exponential phase cells, in contrast to a value of the unity oberved in plateau phase cells, The radiosensitivity of plateau phase cells was somewhat lower compared to exponential phase cells over the range of accumulated doses at the dose rates used. These differences in cellular responses to the radiation between the two phases could be explained by changes in cell proliferation, the redistribution of the cell cycle compartments and the repair capacity of cellular damage during irradiation. (author)

  19. Estimation of growth curve parameters in Konya Merino sheep ...

    African Journals Online (AJOL)

    The objective of this study was to determine the fitness of Quadratic, Cubic, Gompertz and Logistic functions to the growth curves of Konya Merino lambs obtained by using monthly records of live weight from birth to 480 days of age. The models were evaluated according to determination coefficient (R2), mean square ...

  20. Proposal of fatigue crack growth rate curve in air for nickel-base alloys used in BWR

    International Nuclear Information System (INIS)

    Ogawa, Takuya; Itatani, Masao; Nagase, Hiroshi; Aoike, Satoru; Yoneda, Hideki

    2013-01-01

    When the defects are detected in the nuclear components in Japan, structural integrity assessment should be performed for the technical judgment on continuous service based on the Rules on Fitness-for-Service for Nuclear Power Plants of the Japan Society of Mechanical Engineers Code (JSME FFS Code). Fatigue crack growth analysis is required when the cyclic loading would be applied for the components. Recently, fatigue crack growth rate curve in air environment for Nickel-base alloys weld metal used in BWR was proposed by the authors and it was adopted as a code case of JSME FFS Code to evaluate the embedded flaw. In this study, fatigue crack growth behavior for heat-affected zone (HAZ) of Nickel-base alloys in air was investigated. And a unified fatigue crack growth rate curve in air for HAZ and weld metal of Nickel-base alloys used in BWR was evaluated. As a result, it was found that the curve for weld metal could be applied as a curve for both HAZ and weld metal since moderately conservative assessment of fatigue crack growth rate of HAZ is possible by the curve for weld metal in the Paris region. And the threshold value of stress intensity far range (ΔK th ) is determined to 3.0 MPa√m based on the fatigue crack growth rate of HAZ. (author)

  1. An exponential decay model for mediation.

    Science.gov (United States)

    Fritz, Matthew S

    2014-10-01

    Mediation analysis is often used to investigate mechanisms of change in prevention research. Results finding mediation are strengthened when longitudinal data are used because of the need for temporal precedence. Current longitudinal mediation models have focused mainly on linear change, but many variables in prevention change nonlinearly across time. The most common solution to nonlinearity is to add a quadratic term to the linear model, but this can lead to the use of the quadratic function to explain all nonlinearity, regardless of theory and the characteristics of the variables in the model. The current study describes the problems that arise when quadratic functions are used to describe all nonlinearity and how the use of nonlinear functions, such as exponential decay, address many of these problems. In addition, nonlinear models provide several advantages over polynomial models including usefulness of parameters, parsimony, and generalizability. The effects of using nonlinear functions for mediation analysis are then discussed and a nonlinear growth curve model for mediation is presented. An empirical example using data from a randomized intervention study is then provided to illustrate the estimation and interpretation of the model. Implications, limitations, and future directions are also discussed.

  2. AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro

    Directory of Open Access Journals (Sweden)

    Winzer Klaus

    2009-10-01

    Full Text Available Abstract Background Campylobacter jejuni contains a homologue of the luxS gene shown to be responsible for the production of the signalling molecule autoinducer-2 (AI-2 in Vibrio harveyi and Vibrio cholerae. The aim of this study was to determine whether AI-2 acted as a diffusible quorum sensing signal controlling C. jejuni gene expression when it is produced at high levels during mid exponential growth phase. Results AI-2 activity was produced by the parental strain NCTC 11168 when grown in rich Mueller-Hinton broth (MHB as expected, but interestingly was not present in defined Modified Eagles Medium (MEM-α. Consistent with previous studies, the luxS mutant showed comparable growth rates to the parental strain and exhibited decreased motility halos in both MEM-α and MHB. Microarray analysis of genes differentially expressed in wild type and luxS mutant strains showed that many effects on mRNA transcript abundance were dependent on the growth medium and linked to metabolic functions including methionine metabolism. Addition of exogenously produced AI-2 to the wild type and the luxS mutant, growing exponentially in either MHB or MEM-α did not induce any transcriptional changes as analysed by microarray. Conclusion Taken together these results led us to conclude that there is no evidence for the role of AI-2 in cell-to-cell communication in C. jejuni strain NCTC 11168 under the growth conditions used, and that the effects of the luxS mutation on the transcriptome are related to the consequential loss of function in the activated methyl cycle.

  3. AI-2 does not function as a quorum sensing molecule in Campylobacter jejuni during exponential growth in vitro.

    Science.gov (United States)

    Holmes, Kathryn; Tavender, Tim J; Winzer, Klaus; Wells, Jerry M; Hardie, Kim R

    2009-10-08

    Campylobacter jejuni contains a homologue of the luxS gene shown to be responsible for the production of the signalling molecule autoinducer-2 (AI-2) in Vibrio harveyi and Vibrio cholerae. The aim of this study was to determine whether AI-2 acted as a diffusible quorum sensing signal controlling C. jejuni gene expression when it is produced at high levels during mid exponential growth phase. AI-2 activity was produced by the parental strain NCTC 11168 when grown in rich Mueller-Hinton broth (MHB) as expected, but interestingly was not present in defined Modified Eagles Medium (MEM-alpha). Consistent with previous studies, the luxS mutant showed comparable growth rates to the parental strain and exhibited decreased motility halos in both MEM-alpha and MHB. Microarray analysis of genes differentially expressed in wild type and luxS mutant strains showed that many effects on mRNA transcript abundance were dependent on the growth medium and linked to metabolic functions including methionine metabolism. Addition of exogenously produced AI-2 to the wild type and the luxS mutant, growing exponentially in either MHB or MEM-alpha did not induce any transcriptional changes as analysed by microarray. Taken together these results led us to conclude that there is no evidence for the role of AI-2 in cell-to-cell communication in C. jejuni strain NCTC 11168 under the growth conditions used, and that the effects of the luxS mutation on the transcriptome are related to the consequential loss of function in the activated methyl cycle.

  4. The technological singularity and exponential medicine

    Directory of Open Access Journals (Sweden)

    Iraj Nabipour

    2016-01-01

    Full Text Available The "technological singularity" is forecasted to occur in 2045. It is a point when non-biological intelligence becomes more intelligent than humans and each generation of intelligent machines re-designs itself smarter. Beyond this point, there is a symbiosis between machines and humans. This co-existence will produce incredible impacts on medicine that its sparkles could be seen in healthcare industry and the future medicine since 2025. Ray Kurzweil, the great futurist, suggested that three revolutions in science and technology consisting genetic and molecular science, nanotechnology, and robotic (artificial intelligence provided an exponential growth rate for medicine. The "exponential medicine" is going to create more disruptive technologies in healthcare industry. The exponential medicine shifts the paradigm of medical philosophy and produces significant impacts on the healthcare system and patient-physician relationship.   

  5. Exponentiated Lomax Geometric Distribution: Properties and Applications

    Directory of Open Access Journals (Sweden)

    Amal Soliman Hassan

    2017-09-01

    Full Text Available In this paper, a new four-parameter lifetime distribution, called the exponentiated Lomax geometric (ELG is introduced. The new lifetime distribution contains the Lomax geometric and exponentiated Pareto geometric as new sub-models. Explicit algebraic formulas of probability density function, survival and hazard functions are derived. Various structural properties of the new model are derived including; quantile function, Re'nyi entropy, moments, probability weighted moments, order statistic, Lorenz and Bonferroni curves. The estimation of the model parameters is performed by maximum likelihood method and inference for a large sample is discussed. The flexibility and potentiality of the new model in comparison with some other distributions are shown via an application to a real data set. We hope that the new model will be an adequate model for applications in various studies.

  6. Effect of benzalkonium chloride on viability and energy metabolism in exponential- and stationary-growth-phase cells of Listeria monocytogenes.

    Science.gov (United States)

    Luppens, S B; Abee, T; Oosterom, J

    2001-04-01

    The difference in killing exponential- and stationary-phase cells of Listeria monocytogenes by benzalkonium chloride (BAC) was investigated by plate counting and linked to relevant bioenergetic parameters. At a low concentration of BAC (8 mg liter(-1)), a similar reduction in viable cell numbers was observed for stationary-phase cells and exponential-phase cells (an approximately 0.22-log unit reduction), although their membrane potential and pH gradient were dissipated. However, at higher concentrations of BAC, exponential-phase cells were more susceptible than stationary-phase cells. At 25 mg liter(-1), the difference in survival on plates was more than 3 log units. For both types of cells, killing, i.e., more than 1-log unit reduction in survival on plates, coincided with complete inhibition of acidification and respiration and total depletion of ATP pools. Killing efficiency was not influenced by the presence of glucose, brain heart infusion medium, or oxygen. Our results suggest that growth phase is one of the major factors that determine the susceptibility of L. monocytogenes to BAC.

  7. Sensitivity of Fit Indices to Misspecification in Growth Curve Models

    Science.gov (United States)

    Wu, Wei; West, Stephen G.

    2010-01-01

    This study investigated the sensitivity of fit indices to model misspecification in within-individual covariance structure, between-individual covariance structure, and marginal mean structure in growth curve models. Five commonly used fit indices were examined, including the likelihood ratio test statistic, root mean square error of…

  8. Predicting Change in Postpartum Depression: An Individual Growth Curve Approach.

    Science.gov (United States)

    Buchanan, Trey

    Recently, methodologists interested in examining problems associated with measuring change have suggested that developmental researchers should focus upon assessing change at both intra-individual and inter-individual levels. This study used an application of individual growth curve analysis to the problem of maternal postpartum depression.…

  9. The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments

    DEFF Research Database (Denmark)

    Carvalho, Vasco Botelho

    Cellular metabolism can be considered to have two extremes: one is characterized by exponential growth (in 2D cultures) and the other by a dynamic equilibrium (in 3D cultures). We have analysed the proteome and cellular architecture at these two extremes and found that they are dramatically...... different. Ultrastructurally, actin organization is changed, microtubules are increased and keratins 8 and 18 decreased. Metabolically, glycolysis, fatty acid metabolism and the pentose phosphate cycle are increased while Krebs cycle and oxidative phosphorylation is unchanged. Enzymes involved...

  10. Growth Curve Analysis and Change-Points Detection in Extremes

    KAUST Repository

    Meng, Rui

    2016-05-15

    The thesis consists of two coherent projects. The first project presents the results of evaluating salinity tolerance in barley using growth curve analysis where different growth trajectories are observed within barley families. The study of salinity tolerance in plants is crucial to understanding plant growth and productivity. Because fully-automated smarthouses with conveyor systems allow non-destructive and high-throughput phenotyping of large number of plants, it is now possible to apply advanced statistical tools to analyze daily measurements and to study salinity tolerance. To compare different growth patterns of barley variates, we use functional data analysis techniques to analyze the daily projected shoot areas. In particular, we apply the curve registration method to align all the curves from the same barley family in order to summarize the family-wise features. We also illustrate how to use statistical modeling to account for spatial variation in microclimate in smarthouses and for temporal variation across runs, which is crucial for identifying traits of the barley variates. In our analysis, we show that the concentrations of sodium and potassium in leaves are negatively correlated, and their interactions are associated with the degree of salinity tolerance. The second project studies change-points detection methods in extremes when multiple time series data are available. Motived by the scientific question of whether the chances to experience extreme weather are different in different seasons of a year, we develop a change-points detection model to study changes in extremes or in the tail of a distribution. Most of existing models identify seasons from multiple yearly time series assuming a season or a change-point location remains exactly the same across years. In this work, we propose a random effect model that allows the change-point to vary from year to year, following a given distribution. Both parametric and nonparametric methods are developed

  11. Forecasting Financial Extremes: A Network Degree Measure of Super-exponential Growth

    OpenAIRE

    Wanfeng Yan; Edgar van Tuyll van Serooskerken

    2015-01-01

    Investors in stock market are usually greedy during bull markets and scared during bear markets. The greed or fear spreads across investors quickly. This is known as the herding effect, and often leads to a fast movement of stock prices. During such market regimes, stock prices change at a super-exponential rate and are normally followed by a trend reversal that corrects the previous over reaction. In this paper, we construct an indicator to measure the magnitude of the super-exponential grow...

  12. Thermoluminescence under an exponential heating function: I. Theory

    International Nuclear Information System (INIS)

    Kitis, G; Chen, R; Pagonis, V; Carinou, E; Kamenopoulou, V

    2006-01-01

    Constant temperature hot gas readers are widely employed in thermoluminescence dosimetry. In such readers the sample is heated according to an exponential heating function. The single glow-peak shape derived under this heating condition is not described by the TL kinetics equation corresponding to a linear heating rate. In the present work TL kinetics expressions, for first and general order kinetics, describing single glow-peak shapes under an exponential heating function are derived. All expressions were modified from their original form of I(n 0 , E, s, b, T) into I(I m , E, T m , b, T) in order to become more efficient for glow-curve deconvolution analysis. The efficiency of all algorithms was extensively tested using synthetic glow-peaks

  13. Pyridine nucleotide cycling and control of intracellular redox state in relation to poly (ADP-ribose) polymerase activity and nuclear localization of glutathione during exponential growth of Arabidopsis cells in culture.

    Science.gov (United States)

    Pellny, Till K; Locato, Vittoria; Vivancos, Pedro Diaz; Markovic, Jelena; De Gara, Laura; Pallardó, Federico V; Foyer, Christine H

    2009-05-01

    Pyridine nucleotides, ascorbate and glutathione are major redox metabolites in plant cells, with specific roles in cellular redox homeostasis and the regulation of the cell cycle. However, the regulation of these metabolite pools during exponential growth and their precise functions in the cell cycle remain to be characterized. The present analysis of the abundance of ascorbate, glutathione, and pyridine nucleotides during exponential growth of Arabidopsis cells in culture provides evidence for the differential regulation of each of these redox pools. Ascorbate was most abundant early in the growth cycle, but glutathione was low at this point. The cellular ascorbate to dehydroascorbate and reduced glutathione (GSH) to glutathione disulphide ratios were high and constant but the pyridine nucleotide pools were largely oxidized over the period of exponential growth and only became more reduced once growth had ceased. The glutathione pool increased in parallel with poly (ADP-ribose) polymerase (PARP) activities and with increases in the abundance of PARP1 and PARP2 mRNAs at a time of high cell cycle activity as indicated by transcriptome information. Marked changes in the intracellular partitioning of GSH between the cytoplasm and nucleus were observed. Extension of the exponential growth phase by dilution or changing the media led to increases in the glutathione and nicotinamide adenine dinucleotide, oxidized form (NAD)-plus-nicotinamide adenine dinucleotide, reduced form (NADH) pools and to higher NAD/NADH ratios but the nicotinamide adenine dinucleotide phosphate, oxidized form (NADP)-plus-nicotinamide adenine dinucleotide phosphate, reduced form (NADPH) pool sizes, and NAPD/NADPH ratios were much less affected. The ascorbate, glutathione, and pyridine nucleotide pools and PARP activity decreased before the exponential growth phase ended. We conclude that there are marked changes in intracellular redox state during the growth cycle but that redox homeostasis is

  14. Sustaining the Exponential Growth of Embedded Digital Signal Processing Capability

    National Research Council Canada - National Science Library

    Shaw, Gary A; Richards, Mark A

    2004-01-01

    .... We conjecture that as IC shrinkage and attendant performance improvements begin to slow, the exponential rate of improvement we have become accustomed to for embedded applications will be sustainable...

  15. Customized versus population-based growth curves: prediction of low body fat percent at term corrected gestational age following preterm birth.

    Science.gov (United States)

    Law, Tameeka L; Katikaneni, Lakshmi D; Taylor, Sarah N; Korte, Jeffrey E; Ebeling, Myla D; Wagner, Carol L; Newman, Roger B

    2012-07-01

    Compare customized versus population-based growth curves for identification of small-for-gestational-age (SGA) and body fat percent (BF%) among preterm infants. Prospective cohort study of 204 preterm infants classified as SGA or appropriate-for-gestational-age (AGA) by population-based and customized growth curves. BF% was determined by air-displacement plethysmography. Differences between groups were compared using bivariable and multivariable linear and logistic regression analyses. Customized curves reclassified 30% of the preterm infants as SGA. SGA infants identified by customized method only had significantly lower BF% (13.8 ± 6.0) than the AGA (16.2 ± 6.3, p = 0.02) infants and similar to the SGA infants classified by both methods (14.6 ± 6.7, p = 0.51). Customized growth curves were a significant predictor of BF% (p = 0.02), whereas population-based growth curves were not a significant independent predictor of BF% (p = 0.50) at term corrected gestational age. Customized growth potential improves the differentiation of SGA infants and low BF% compared with a standard population-based growth curve among a cohort of preterm infants.

  16. An integral parametrization of the bacterial growth curve experimental demonstration with E. coli C600 bacteria

    International Nuclear Information System (INIS)

    Garces, F.; Vidania, R. de

    1984-01-01

    In this work an integral parametrization of the bacterial growth curve is presented. The values of the parameters are obtained by fitting to the experimental data. Those parameters, with allow to describe the growth in its different phases, are the followings: slopes of the curve in its three parts and the time which divides the last two phases of the bacterial growth. The experimental data are bacterial densities measured by optical methods. The bacteria used was the E. coli C 6 00. (Author)

  17. Exponential model normalization for electrical capacitance tomography with external electrodes under gap permittivity conditions

    International Nuclear Information System (INIS)

    Baidillah, Marlin R; Takei, Masahiro

    2017-01-01

    A nonlinear normalization model which is called exponential model for electrical capacitance tomography (ECT) with external electrodes under gap permittivity conditions has been developed. The exponential model normalization is proposed based on the inherently nonlinear relationship characteristic between the mixture permittivity and the measured capacitance due to the gap permittivity of inner wall. The parameters of exponential equation are derived by using an exponential fitting curve based on the simulation and a scaling function is added to adjust the experiment system condition. The exponential model normalization was applied to two dimensional low and high contrast dielectric distribution phantoms by using simulation and experimental studies. The proposed normalization model has been compared with other normalization models i.e. Parallel, Series, Maxwell and Böttcher models. Based on the comparison of image reconstruction results, the exponential model is reliable to predict the nonlinear normalization of measured capacitance in term of low and high contrast dielectric distribution. (paper)

  18. Parent Involvement and Science Achievement: A Cross-Classified Multilevel Latent Growth Curve Analysis

    Science.gov (United States)

    Johnson, Ursula Y.; Hull, Darrell M.

    2014-01-01

    The authors examined science achievement growth at Grades 3, 5, and 8 and parent school involvement at the same time points using the Early Childhood Longitudinal Study-Kindergarten Class of 1998-1999. Data were analyzed using cross-classified multilevel latent growth curve modeling with time invariant and varying covariates. School-based…

  19. Using Growth Curves To Determine the Timing of the Booster Sessions.

    Science.gov (United States)

    Hennessy, Michael; Bolan, Gail A.; Hoxworth, Tamara; Iatesta, Michael; Rhodes, Fen; Zenilman, Jonathan M.

    1999-01-01

    Demonstrates an application of a method for using growth curves to determine the timing of booster sessions to reinforce the cognitive messages or behavior changes of interventions. Uses data from a multisite randomized experiment that compared three counseling and testing methods for preventing sexual disease transmission. Presents…

  20. Genome association study through nonlinear mixed models revealed new candidate genes for pig growth curves

    Directory of Open Access Journals (Sweden)

    Fabyano Fonseca e Silva

    Full Text Available ABSTRACT: Genome association analyses have been successful in identifying quantitative trait loci (QTLs for pig body weights measured at a single age. However, when considering the whole weight trajectories over time in the context of genome association analyses, it is important to look at the markers that affect growth curve parameters. The easiest way to consider them is via the two-step method, in which the growth curve parameters and marker effects are estimated separately, thereby resulting in a reduction of the statistical power and the precision of estimates. One efficient solution is to adopt nonlinear mixed models (NMM, which enables a joint modeling of the individual growth curves and marker effects. Our aim was to propose a genome association analysis for growth curves in pigs based on NMM as well as to compare it with the traditional two-step method. In addition, we also aimed to identify the nearest candidate genes related to significant SNP (single nucleotide polymorphism markers. The NMM presented a higher number of significant SNPs for adult weight (A and maturity rate (K, and provided a direct way to test SNP significance simultaneously for both the A and K parameters. Furthermore, all significant SNPs from the two-step method were also reported in the NMM analysis. The ontology of the three candidate genes (SH3BGRL2, MAPK14, and MYL9 derived from significant SNPs (simultaneously affecting A and K allows us to make inferences with regards to their contribution to the pig growth process in the population studied.

  1. A sigmoidal fit for pressure-volume curves of idiopathic pulmonary fibrosis patients on mechanical ventilation: clinical implications

    Directory of Open Access Journals (Sweden)

    Juliana C. Ferreira

    2011-01-01

    Full Text Available OBJECTIVE: Respiratory pressure-volume curves fitted to exponential equations have been used to assess disease severity and prognosis in spontaneously breathing patients with idiopathic pulmonary fibrosis. Sigmoidal equations have been used to fit pressure-volume curves for mechanically ventilated patients but not for idiopathic pulmonary fibrosis patients. We compared a sigmoidal model and an exponential model to fit pressure-volume curves from mechanically ventilated patients with idiopathic pulmonary fibrosis. METHODS: Six idiopathic pulmonary fibrosis patients and five controls underwent inflation pressure-volume curves using the constant-flow technique during general anesthesia prior to open lung biopsy or thymectomy. We identified the lower and upper inflection points and fit the curves with an exponential equation, V = A-B.e-k.P, and a sigmoid equation, V = a+b/(1+e-(P-c/d. RESULTS: The mean lower inflection point for idiopathic pulmonary fibrosis patients was significantly higher (10.5 ± 5.7 cm H2O than that of controls (3.6 ± 2.4 cm H2O. The sigmoidal equation fit the pressure-volume curves of the fibrotic and control patients well, but the exponential equation fit the data well only when points below 50% of the inspiratory capacity were excluded. CONCLUSION: The elevated lower inflection point and the sigmoidal shape of the pressure-volume curves suggest that respiratory system compliance is decreased close to end-expiratory lung volume in idiopathic pulmonary fibrosis patients under general anesthesia and mechanical ventilation. The sigmoidal fit was superior to the exponential fit for inflation pressure-volume curves of anesthetized patients with idiopathic pulmonary fibrosis and could be useful for guiding mechanical ventilation during general anesthesia in this condition.

  2. Growth curve of buffalo grazing on a grass pasture

    Directory of Open Access Journals (Sweden)

    Teresa Cristina Alves

    2015-09-01

    Full Text Available ABSTRACTThe objective of this study was to evaluate the performance of 17 buffaloes (Mediterranean, from birth to slaughter age (720 days with monthly measures of weight, thoracic perimeter, body length, and height at withers. At the end of experimental period, the animals were separated into two different groups for statistical analysis according to slaughter weight: light body weight (LBW, mean 517 kg and heavy body weight (HBW, mean 568 kg. Buffalo growth occurs in the same way up to weaning age, and after that, two distinct groups grow in different forms in the same conditions of management and feeding. Body weight can be estimated according to age, thoracic perimeter, height, and length, showing high correlations. Buffaloes show growth in a sigmoid-curve model.

  3. Approximate models for the study of exponential changed quantities: Application on the plasma waves growth rate or damping

    International Nuclear Information System (INIS)

    Xaplanteris, C. L.; Xaplanteris, L. C.; Leousis, D. P.

    2014-01-01

    Many physical phenomena that concern the research these days are basically complicated because of being multi-parametric. Thus, their study and understanding meets with big if not unsolved obstacles. Such complicated and multi-parametric is the plasmatic state as well, where the plasma and the physical quantities that appear along with it have chaotic behavior. Many of those physical quantities change exponentially and at most times they are stabilized by presenting wavy behavior. Mostly in the transitive state rather than the steady state, the exponentially changing quantities (Growth, Damping etc) depend on each other in most cases. Thus, it is difficult to distinguish the cause from the result. The present paper attempts to help this difficult study and understanding by proposing mathematical exponential models that could relate with the study and understanding of the plasmatic wavy instability behavior. Such instabilities are already detected, understood and presented in previous publications of our laboratory. In other words, our new contribution is the study of the already known plasmatic quantities by using mathematical models (modeling and simulation). These methods are both useful and applicable in the chaotic theory. In addition, our ambition is to also conduct a list of models useful for the study of chaotic problems, such as those that appear into the plasma, starting with this paper's examples

  4. Approximate models for the study of exponential changed quantities: Application on the plasma waves growth rate or damping

    Energy Technology Data Exchange (ETDEWEB)

    Xaplanteris, C. L., E-mail: cxaplanteris@yahoo.com [Plasma Physics Laboratory, IMS, NCSR “Demokritos”, Athens, Greece and Hellenic Army Academy, Vari Attica (Greece); Xaplanteris, L. C. [School of Physics, National and Kapodistrian University of Athens, Athens (Greece); Leousis, D. P. [Technical High School of Athens, Athens (Greece)

    2014-03-15

    Many physical phenomena that concern the research these days are basically complicated because of being multi-parametric. Thus, their study and understanding meets with big if not unsolved obstacles. Such complicated and multi-parametric is the plasmatic state as well, where the plasma and the physical quantities that appear along with it have chaotic behavior. Many of those physical quantities change exponentially and at most times they are stabilized by presenting wavy behavior. Mostly in the transitive state rather than the steady state, the exponentially changing quantities (Growth, Damping etc) depend on each other in most cases. Thus, it is difficult to distinguish the cause from the result. The present paper attempts to help this difficult study and understanding by proposing mathematical exponential models that could relate with the study and understanding of the plasmatic wavy instability behavior. Such instabilities are already detected, understood and presented in previous publications of our laboratory. In other words, our new contribution is the study of the already known plasmatic quantities by using mathematical models (modeling and simulation). These methods are both useful and applicable in the chaotic theory. In addition, our ambition is to also conduct a list of models useful for the study of chaotic problems, such as those that appear into the plasma, starting with this paper's examples.

  5. Investigation of the growth patterns of non-functioning pituitary macroadenomas using volumetric assessments on serial MRI investigations

    Directory of Open Access Journals (Sweden)

    Jaco Pieterse

    2016-07-01

    Full Text Available Background: Benign non-functioning pituitary macroadenomas (NFMA often cause mass effect on the optic chiasm necessitating transsphenoidal surgery to prevent blindness.However, surgery is complicated and there is a high tumour recurrence rate. Currently, very little is known about the natural (and residual post-surgical growth patterns of these NFMA. Conflicting data describe decreased growth to exponential growth over various time periods.Due to lack of information on growth dynamics of these NFMA, suitable follow-up imaging protocols have not been described to date. Objective: To determine if NFMA grow or stay quiescent over a time period using serial MRI investigations and a stereo logical method to determine tumour volume. In addition, to evaluate if NFMA adhere to a certain growth pattern or grow at random. Method: Thirteen patients with NFMA had serial MRI investigations over a 73-month period at the Universitas Academic Hospital. Six of the selected patients had undergone previous surgery, while seven patients had received no medical or surgical intervention. By using astereological method, tumour volumes were calculated and plotted over time to demonstrate growth curves. The data were then fitted to tumour growth models already described in literature in order to obtain the best fit by calculating the r2 value. Results: Positive tumour growth was demonstrated in all cases. Tumour growth patterns of nine patients best fitted the exponential growth curve while the growth patterns of three patients best fitted the logistic growth curve. The remaining patient demonstrated a linear growth pattern. Conclusion: A specific growth model best described tumour growth observed in non-surgical and surgical cases. If follow-up imaging confirms positive growth, future growth can be predicted by extrapolation. This information can then be used to determine the relevant follow-up-imaging interval in each individual patient.

  6. Standardized Percentile Curves of Body Mass Index of Northeast Iranian Children Aged 25 to 60 Months

    Science.gov (United States)

    Emdadi, Maryam; Safarian, Mohammad; Doosti, Hassan

    2011-01-01

    Objective Growth charts are widely used to assess children's growth status and can provide a trajectory of growth during early important months of life. Racial differences necessitate using local growth charts. This study aimed to provide standardized growth curves of body mass index (BMI) for children living in northeast Iran. Methods A total of 23730 apparently healthy boys and girls aged 25 to 60 months recruited for 20 days from those attending community clinics for routine health checks. Anthropometric measurements were done by trained health staff using WHO methodology. The LMSP method with maximum penalized likelihood, the Generalized Additive Models, the Box-Cox power exponential distribution distribution, Akaike Information Criteria and Generalized Akaike Criteria with penalty equal to 3 [GAIC(3)], and Worm plot and Q-tests as goodness of fit tests were used to construct the centile reference charts. Findings The BMI centile curves for boys and girls aged 25 to 60 months were drawn utilizing a population of children living in northeast Iran. Conclusion The results of the current study demonstrate the possibility of preparation of local growth charts and their importance in evaluating children's growth. Also their differences, relative to those prepared by global references, reflect the necessity of preparing local charts in future studies using longitudinal data. PMID:23056770

  7. Modeling pitting growth data and predicting degradation trend

    International Nuclear Information System (INIS)

    Viglasky, T.; Awad, R.; Zeng, Z.; Riznic, J.

    2007-01-01

    A non-statistical modeling approach to predict material degradation is presented in this paper. In this approach, the original data series is processed using Accumulated Generating Operation (AGO). With the aid of the AGO which weakens the random fluctuation embedded in the data series, an approximately exponential curve is established. The generated data series described by the exponential curve is then modeled by a differential equation. The coefficients of the differential equation can be deduced by approximate difference formula based on least-squares algorithm. By solving the differential equation and processing an inverse AGO, a predictive model can be obtained. As this approach is not established on the basis of statistics, the prediction can be performed with a limited amount of data. Implementation of this approach is demonstrated by predicting the pitting growth rate in specimens and wear trend in steam generator tubes. The analysis results indicate that this approach provides a powerful tool with reasonable precision to predict material degradation. (author)

  8. On the analysis of Canadian Holstein dairy cow lactation curves using standard growth functions.

    Science.gov (United States)

    López, S; France, J; Odongo, N E; McBride, R A; Kebreab, E; AlZahal, O; McBride, B W; Dijkstra, J

    2015-04-01

    Six classical growth functions (monomolecular, Schumacher, Gompertz, logistic, Richards, and Morgan) were fitted to individual and average (by parity) cumulative milk production curves of Canadian Holstein dairy cows. The data analyzed consisted of approximately 91,000 daily milk yield records corresponding to 122 first, 99 second, and 92 third parity individual lactation curves. The functions were fitted using nonlinear regression procedures, and their performance was assessed using goodness-of-fit statistics (coefficient of determination, residual mean squares, Akaike information criterion, and the correlation and concordance coefficients between observed and adjusted milk yields at several days in milk). Overall, all the growth functions evaluated showed an acceptable fit to the cumulative milk production curves, with the Richards equation ranking first (smallest Akaike information criterion) followed by the Morgan equation. Differences among the functions in their goodness-of-fit were enlarged when fitted to average curves by parity, where the sigmoidal functions with a variable point of inflection (Richards and Morgan) outperformed the other 4 equations. All the functions provided satisfactory predictions of milk yield (calculated from the first derivative of the functions) at different lactation stages, from early to late lactation. The Richards and Morgan equations provided the most accurate estimates of peak yield and total milk production per 305-d lactation, whereas the least accurate estimates were obtained with the logistic equation. In conclusion, classical growth functions (especially sigmoidal functions with a variable point of inflection) proved to be feasible alternatives to fit cumulative milk production curves of dairy cows, resulting in suitable statistical performance and accurate estimates of lactation traits. Copyright © 2015 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  9. Statistical analysis of time-resolved emission from ensembles of semiconductor quantum dots: Interpretation of exponential decay models

    DEFF Research Database (Denmark)

    Van Driel, A.F.; Nikolaev, I.S.; Vergeer, P.

    2007-01-01

    We present a statistical analysis of time-resolved spontaneous emission decay curves from ensembles of emitters, such as semiconductor quantum dots, with the aim of interpreting ubiquitous non-single-exponential decay. Contrary to what is widely assumed, the density of excited emitters...... and the intensity in an emission decay curve are not proportional, but the density is a time integral of the intensity. The integral relation is crucial to correctly interpret non-single-exponential decay. We derive the proper normalization for both a discrete and a continuous distribution of rates, where every...... decay component is multiplied by its radiative decay rate. A central result of our paper is the derivation of the emission decay curve when both radiative and nonradiative decays are independently distributed. In this case, the well-known emission quantum efficiency can no longer be expressed...

  10. Exponential growth and Gaussian-like fluctuations of solutions of stochastic differential equations with maximum functionals

    International Nuclear Information System (INIS)

    Appleby, J A D; Wu, H

    2008-01-01

    In this paper we consider functional differential equations subjected to either instantaneous state-dependent noise, or to a white noise perturbation. The drift of the equations depend linearly on the current value and on the maximum of the solution. The functional term always provides positive feedback, while the instantaneous term can be mean-reverting or can exhibit positive feedback. We show in the white noise case that if the instantaneous term is mean reverting and dominates the history term, then solutions are recurrent, and upper bounds on the a.s. growth rate of the partial maxima of the solution can be found. When the instantaneous term is weaker, or is of positive feedback type, we determine necessary and sufficient conditions on the diffusion coefficient which ensure the exact exponential growth of solutions. An application of these results to an inefficient financial market populated by reference traders and speculators is given, in which the difference between the current instantaneous returns and maximum of the returns over the last few time units is used to determine trading strategies.

  11. Growth curves of preschool children in the northeast of iran: a population based study using quantile regression approach.

    Science.gov (United States)

    Payande, Abolfazl; Tabesh, Hamed; Shakeri, Mohammad Taghi; Saki, Azadeh; Safarian, Mohammad

    2013-01-14

    Growth charts are widely used to assess children's growth status and can provide a trajectory of growth during early important months of life. The objectives of this study are going to construct growth charts and normal values of weight-for-age for children aged 0 to 5 years using a powerful and applicable methodology. The results compare with the World Health Organization (WHO) references and semi-parametric LMS method of Cole and Green. A total of 70737 apparently healthy boys and girls aged 0 to 5 years were recruited in July 2004 for 20 days from those attending community clinics for routine health checks as a part of a national survey. Anthropometric measurements were done by trained health staff using WHO methodology. The nonparametric quantile regression method obtained by local constant kernel estimation of conditional quantiles curves using for estimation of curves and normal values. The weight-for-age growth curves for boys and girls aged from 0 to 5 years were derived utilizing a population of children living in the northeast of Iran. The results were similar to the ones obtained by the semi-parametric LMS method in the same data. Among all age groups from 0 to 5 years, the median values of children's weight living in the northeast of Iran were lower than the corresponding values in WHO reference data. The weight curves of boys were higher than those of girls in all age groups. The differences between growth patterns of children living in the northeast of Iran versus international ones necessitate using local and regional growth charts. International normal values may not properly recognize the populations at risk for growth problems in Iranian children. Quantile regression (QR) as a flexible method which doesn't require restricted assumptions, proposed for estimation reference curves and normal values.

  12. Growth rates in modern speleothems from Santana Cave, Brazil, by the 210Pb-method

    International Nuclear Information System (INIS)

    Bonotto, D.M.; Karmann, I.; Baskaran, M.M.

    2012-01-01

    The Santana Cave is located at the Upper Ribeira Touristic State Park (PETAR-Parque Estadual Turístico do Alto Ribeira) in southern São Paulo State, Brazil. This paper describes 210 Pb activity concentration data in soda straw stalactites samples collected at Salão das Flores in Santana Cave that is a fossil tributary of the cave river. Non-expensive alpha counting following some analytical steps for extracting and depositing 210 Po were used for providing the 210 Pb data. In the analyzed samples, 210 Pb values of increasingly older samples fitted an exponential curve, thus suggesting that the production of 210 Pb has been constant with time. Also, the near-ideal fit indicated that the growth was uniform and there was no break in the continuous growth. The soda straw growth rates were determined from the best fit to the exponential curve through the 210 Pb activity concentration. The results of the measurements allowed estimate a longitudinal rate corresponding to 1.3 mm/yr and a lateral rate of 0.01 mm/yr, which permitted calculate times of 70 years and 317–498 years for their formation, respectively. The lateral growth rate is compatible with values from studies of chemical weathering rates held under laboratory and natural conditions.

  13. Curve Modulation and Apex Migration Using Shilla Growth Guidance Rods for Early-onset Scoliosis at 5-Year Follow-up.

    Science.gov (United States)

    Wilkinson, John T; Songy, Chad E; Bumpass, David B; McCullough, Francis L; McCarthy, Richard E

    2017-04-03

    The Shilla procedure was designed to correct and control early-onset spinal deformity while harnessing a child's remaining spinal growth. It allows for controlled axial skeletal growth within the construct, avoiding the need for frequent surgeries to lengthen implants. We hypothesized that curve characteristics evolve over time after initial apex fusion and placement of the Shilla implants. The purpose of this study was to identify trends in curve evolution after Shilla implantation and understand how these changes influence ultimate outcome. A single-center, retrospective review of all patients with Shilla implants in place for ≥5 years yielded 21 patients. Charts and radiographs were reviewed to compare coronal curve characteristics preoperatively, postoperatively, and at last follow-up to note changes in the apex of the primary curve. Also noted were the development of adjacent compensatory curves, the overall vertical spinal growth, and the need for definitive spinal fusion once skeletal maturity was reached. Of the 21 patients, the curve apex migrated caudally in 12 patients (57%) and cephalad in 1 patient (5%), with a mean migration of 2.7 vertebral levels. Two patients (10%) developed new, significant compensatory curves (1 caudal and 1 cephalad). All patients demonstrated spinal growth in T1-S1 length following index surgery (mean, 45 mm). At skeletal maturity, 10 patients underwent definitive posterior spinal fusion and instrumentation, and 3 underwent implant removal alone. This study constitutes the longest follow-up of Shilla patients evaluating curve and implant behavior. Results of this review suggest that the apex of the fused primary curve shifts in approximately 62% of patients, with nearly all of these (92%) involving a distal migration. Compensatory curves did develop after Shilla placement as well. Overall, these findings represent adding-on distal to the apex after Shilla instrumentation rather than a crankshaft phenomenon about the apex. A

  14. Evaluation of water beef buffalo from birth to two years using different growth curves

    Directory of Open Access Journals (Sweden)

    W.R. Lamberson

    2010-02-01

    Full Text Available The buffalo is a domestic animal species of growing world-wide importance. Research to improve genetic improvement programs is important to maintain the productivity of buffalo. The objective this research was to evaluate the growth of Brazilian buffalo to two years of age with different growth curves. Growth curves consolidate the information contained in the weight-age data into three or four biologically meaningful parameters. The data included 31,452 weights at birth and 120, 205, 365, 550 and 730 days of buffalo (n = 5,178 raised on pasture without supplementation. Logistic, Gompertz, quadratic logarithmic, and linear hyperbolic curves (designated L, G, QL, and LH, respectively were fitted to the data by using proc NLIN of SAS (SAS Institute, Inc., Cary, NC, USA. The parameters estimates for L [WT= A * (((1 + exp (-k * AGE**-m] were A = 865.1 ± 5.42; k= 0.0028 ± 0.00002; M= 3.808 ± 0.007; R2 = 0.95. For G [WT= A * exp (-b * exp (-k * age] the parameters estimates were A= 967.6 ± 7.23; k = 0.00217 ± 0.000015; b = -2.8152 ± 0.00532. For QL [WT= A + b*age + k*(age*age + m*log (age] parameters estimates were A= 37.41 ± 0.48; k= 0.00019 ± 6.4E-6; b= 0.539 ± 0.006; m= 2.32 ± 0.23; R2=0.96. For LH [WT= A + b*AGE + k*(1/AGE] the parameters estimates were A= 23.15 ± 0.44; k=15.16 ± 0.66; b= 0.707 ± 0.001; R2= 0.96. Each of these curves fit these data equally well and could be used for characterizing growth to two years in beef buffalo.

  15. Estimation of the growth curve and heritability of the growth rate for giant panda (Ailuropoda melanoleuca) cubs.

    Science.gov (United States)

    Che, T D; Wang, C D; Jin, L; Wei, M; Wu, K; Zhang, Y H; Zhang, H M; Li, D S

    2015-03-27

    Giant panda cubs have a low survival rate during the newborn and early growth stages. However, the growth and developmental parameters of giant panda cubs during the early lactation stage (from birth to 6 months) are not well known. We examined the growth and development of giant panda cubs by the Chapman growth curve model and estimated the heritability of the maximum growth rate at the early lactation stage. We found that 83 giant panda cubs reached their maximum growth rate at approximately 75-120 days after birth. The body weight of cubs at 75 days was 4285.99 g. Furthermore, we estimated that the heritability of the maximum growth rate was moderate (h(2) = 0.38). Our study describes the growth and development of giant panda cubs at the early lactation stage and provides valuable growth benchmarks. We anticipate that our results will be a starting point for more detailed research on increasing the survival rate of giant panda cubs. Feeding programs for giant panda cubs need further improvement.

  16. Task-based detectability comparison of exponential transformation of free-response operating characteristic (EFROC) curve and channelized Hotelling observer (CHO)

    Science.gov (United States)

    Khobragade, P.; Fan, Jiahua; Rupcich, Franco; Crotty, Dominic J.; Gilat Schmidt, Taly

    2016-03-01

    This study quantitatively evaluated the performance of the exponential transformation of the free-response operating characteristic curve (EFROC) metric, with the Channelized Hotelling Observer (CHO) as a reference. The CHO has been used for image quality assessment of reconstruction algorithms and imaging systems and often it is applied to study the signal-location-known cases. The CHO also requires a large set of images to estimate the covariance matrix. In terms of clinical applications, this assumption and requirement may be unrealistic. The newly developed location-unknown EFROC detectability metric is estimated from the confidence scores reported by a model observer. Unlike the CHO, EFROC does not require a channelization step and is a non-parametric detectability metric. There are few quantitative studies available on application of the EFROC metric, most of which are based on simulation data. This study investigated the EFROC metric using experimental CT data. A phantom with four low contrast objects: 3mm (14 HU), 5mm (7HU), 7mm (5 HU) and 10 mm (3 HU) was scanned at dose levels ranging from 25 mAs to 270 mAs and reconstructed using filtered backprojection. The area under the curve values for CHO (AUC) and EFROC (AFE) were plotted with respect to different dose levels. The number of images required to estimate the non-parametric AFE metric was calculated for varying tasks and found to be less than the number of images required for parametric CHO estimation. The AFE metric was found to be more sensitive to changes in dose than the CHO metric. This increased sensitivity and the assumption of unknown signal location may be useful for investigating and optimizing CT imaging methods. Future work is required to validate the AFE metric against human observers.

  17. Windowed direct exponential curve resolution quantification of nuclear magnetic resonance spectroscopy with applications to amniotic fluid metabonomics

    International Nuclear Information System (INIS)

    Botros, L.L.

    2007-01-01

    This thesis presents a quantitative protocol of proton nuclear magnetic resonance ( 1 H NMR) that allows the determination of human amniotic fluid metabolite concentrations, which are then used in a metabonomic study to establish patient health during gestation. 1 H NMR free inductive decays (FIDs) of 258 human amniotic fluid samples from a 500MHz spectrometer are acquired. Quantitative analyses methods in both the frequency- and time-domain are carried out and compared. Frequency-domain analysis is accomplished by integration of the metabolite peaks before and after the inclusion of a known standard addition of alanine. Time-domain analysis is accomplished by the direct exponential curve resolution algorithm (DECRA). Both techniques are assessed by applications to calibration biological solutions and a simulated data set. The DECRA method proves to be a more accurate and precise route for quantitative analysis, and is included in the developed protocol. Well-defined peaks of various components are visible in the frequency-domain 1 H NMR spectra, including lactate, alanine, acetate, citrate, choline, glycine, and glucose. All are quantified with the proposed protocol. Statistical t-test and notched box and whisker plots are used to compare means of metabolite concentrations for diabetic and normal patients. Glucose, glycine, and choline are all found to correlate with gestational diabetes mellitus early in gestation. With further development, time-domain quantitative 1 H NMR has potential to become a robust diagnostic tool for gestational health. (author)

  18. Windowed direct exponential curve resolution quantification of nuclear magnetic resonance spectroscopy with applications to amniotic fluid metabonomics

    Energy Technology Data Exchange (ETDEWEB)

    Botros, L.L

    2007-07-01

    This thesis presents a quantitative protocol of proton nuclear magnetic resonance ({sup 1}H NMR) that allows the determination of human amniotic fluid metabolite concentrations, which are then used in a metabonomic study to establish patient health during gestation. {sup 1}H NMR free inductive decays (FIDs) of 258 human amniotic fluid samples from a 500MHz spectrometer are acquired. Quantitative analyses methods in both the frequency- and time-domain are carried out and compared. Frequency-domain analysis is accomplished by integration of the metabolite peaks before and after the inclusion of a known standard addition of alanine. Time-domain analysis is accomplished by the direct exponential curve resolution algorithm (DECRA). Both techniques are assessed by applications to calibration biological solutions and a simulated data set. The DECRA method proves to be a more accurate and precise route for quantitative analysis, and is included in the developed protocol. Well-defined peaks of various components are visible in the frequency-domain {sup 1}H NMR spectra, including lactate, alanine, acetate, citrate, choline, glycine, and glucose. All are quantified with the proposed protocol. Statistical t-test and notched box and whisker plots are used to compare means of metabolite concentrations for diabetic and normal patients. Glucose, glycine, and choline are all found to correlate with gestational diabetes mellitus early in gestation. With further development, time-domain quantitative {sup 1}H NMR has potential to become a robust diagnostic tool for gestational health. (author)

  19. The Existence of Weak D-Pullback Exponential Attractor for Nonautonomous Dynamical System

    Directory of Open Access Journals (Sweden)

    Yongjun Li

    2016-01-01

    Full Text Available First, for a process U(t,τ∣t≥τ, we introduce a new concept, called the weak D-pullback exponential attractor, which is a family of sets M(t∣t≤T, for any T∈R, satisfying the following: (i M(t is compact, (ii M(t is positively invariant, that is, U(t,τM(τ⊂M(t, and (iii there exist k,l>0 such that dist(U(t,τB(τ,M(t≤ke-(t-τ; that is, M(t pullback exponential attracts B(τ. Then we give a method to obtain the existence of weak D-pullback exponential attractors for a process. As an application, we obtain the existence of weak D-pullback exponential attractor for reaction diffusion equation in H01 with exponential growth of the external force.

  20. Relationship Between Crack Growth Resistance KR Curve and Specimen Width for 2060 - T8E30 Lithium Aluminum Alloy

    Directory of Open Access Journals (Sweden)

    Tong Di Hua

    2016-01-01

    Full Text Available KR crack growth resistance curve can be used to predict crack propagation behavior, estimate the crack component bearing capacity after the crack, so KR curve research occupies very important position in the fracture mechanics. Based on crack growth resistance KR test curve of 2060 - T8E30 lithium aluminum alloy under the same thickness for different width, studies have shown that under the same thickness, the influence of the width on the resistance curve of crack propagation can be neglected. Empirical equation of resistance curve of crack extension of the smaller width specimen is given. Extending the fitting equation to that of larger width, it can be found that it is highly coincided with the experimental results.

  1. Estimation of heritability and genetic correlation of body weight gain and growth curve parameters in Korean native chicken

    Directory of Open Access Journals (Sweden)

    Prabuddha Manjula

    2018-01-01

    Full Text Available Objective This study estimated the genetic parameters for body weight gain and growth curve parameter traits in Korean native chicken (KNC. Methods A total of 585 F1 chickens were used along with 88 of their F0 birds. Body weights were measured every 2 weeks from hatching to 20 weeks of age to measure weight gain at 2-week intervals. For each individual, a logistic growth curve model was fitted to the longitudinal growth dataset to obtain three growth curve parameters (α, asymptotic final body weight; β, inflection point; and γ, constant scale that was proportional to the overall growth rate. Genetic parameters were estimated based on the linear-mixed model using a restricted maximum likelihood method. Results Heritability estimates of body weight gain traits were low to high (0.057 to 0.458. Heritability estimates for α, β, and γ were 0.211±0.08, 0.249±0.09, and 0.095±0.06, respectively. Both genetic and phenotypic correlations between weight gain traits ranged from −0.527 to 0.993. Genetic and phenotypic correlation between the growth curve parameters and weight gain traits ranged from −0.968 to 0.987. Conclusion Based on the results of this study population, we suggest that the KNC could be used for selective breeding between 6 and 8 weeks of age to enhance the overall genetic improvement of growth traits. After validation of these results in independent studies, these findings will be useful for further optimization of breeding programs for KNC.

  2. Candidate genes and growth curves for adiposity in African- and European-American youth

    NARCIS (Netherlands)

    Podolsky, R. H.; Barbeau, P.; Kang, H-S; Zhu, H.; Treiber, F. A.; Snieder, H.

    2007-01-01

    Objective: Obesity is associated with multiple health problems and often originates in childhood. This study investigated the association of genes with the development of general and central obesity from childhood into adulthood. Design: Individual growth curves for measures of general adiposity

  3. Extended Poisson Exponential Distribution

    Directory of Open Access Journals (Sweden)

    Anum Fatima

    2015-09-01

    Full Text Available A new mixture of Modified Exponential (ME and Poisson distribution has been introduced in this paper. Taking the Maximum of Modified Exponential random variable when the sample size follows a zero truncated Poisson distribution we have derived the new distribution, named as Extended Poisson Exponential distribution. This distribution possesses increasing and decreasing failure rates. The Poisson-Exponential, Modified Exponential and Exponential distributions are special cases of this distribution. We have also investigated some mathematical properties of the distribution along with Information entropies and Order statistics of the distribution. The estimation of parameters has been obtained using the Maximum Likelihood Estimation procedure. Finally we have illustrated a real data application of our distribution.

  4. 51Cr - erythrocyte survival curves

    International Nuclear Information System (INIS)

    Paiva Costa, J. de.

    1982-07-01

    Sixteen patients were studied, being fifteen patients in hemolytic state, and a normal individual as a witness. The aim was to obtain better techniques for the analysis of the erythrocytes, survival curves, according to the recommendations of the International Committee of Hematology. It was used the radiochromatic method as a tracer. Previously a revisional study of the International Literature was made in its aspects inherent to the work in execution, rendering possible to establish comparisons and clarify phonomena observed in cur investigation. Several parameters were considered in this study, hindering both the exponential and the linear curves. The analysis of the survival curves of the erythrocytes in the studied group, revealed that the elution factor did not present a homogeneous answer quantitatively to all, though, the result of the analysis of these curves have been established, through listed programs in the electronic calculator. (Author) [pt

  5. The standard centrifuge method accurately measures vulnerability curves of long-vesselled olive stems.

    Science.gov (United States)

    Hacke, Uwe G; Venturas, Martin D; MacKinnon, Evan D; Jacobsen, Anna L; Sperry, John S; Pratt, R Brandon

    2015-01-01

    The standard centrifuge method has been frequently used to measure vulnerability to xylem cavitation. This method has recently been questioned. It was hypothesized that open vessels lead to exponential vulnerability curves, which were thought to be indicative of measurement artifact. We tested this hypothesis in stems of olive (Olea europea) because its long vessels were recently claimed to produce a centrifuge artifact. We evaluated three predictions that followed from the open vessel artifact hypothesis: shorter stems, with more open vessels, would be more vulnerable than longer stems; standard centrifuge-based curves would be more vulnerable than dehydration-based curves; and open vessels would cause an exponential shape of centrifuge-based curves. Experimental evidence did not support these predictions. Centrifuge curves did not vary when the proportion of open vessels was altered. Centrifuge and dehydration curves were similar. At highly negative xylem pressure, centrifuge-based curves slightly overestimated vulnerability compared to the dehydration curve. This divergence was eliminated by centrifuging each stem only once. The standard centrifuge method produced accurate curves of samples containing open vessels, supporting the validity of this technique and confirming its utility in understanding plant hydraulics. Seven recommendations for avoiding artefacts and standardizing vulnerability curve methodology are provided. © 2014 The Authors. New Phytologist © 2014 New Phytologist Trust.

  6. Ion transfer through solvent polymeric membranes driven by an exponential current flux.

    Science.gov (United States)

    Molina, A; Torralba, E; González, J; Serna, C; Ortuño, J A

    2011-03-21

    General analytical equations which govern ion transfer through liquid membranes with one and two polarized interfaces driven by an exponential current flux are derived. Expressions for the transient and stationary E-t, dt/dE-E and dI/dE-E curves are obtained, and the evolution from transient to steady behaviour has been analyzed in depth. We have also shown mathematically that the voltammetric and stationary chronopotentiometric I(N)-E curves are identical (with E being the applied potential for voltammetric techniques and the measured potential for chronopotentiometric techniques), and hence, their derivatives provide identical information.

  7. The Effect of Divergent Selection on 4-wk BW on the Shape of Growth Curve in Japanese Quail

    Directory of Open Access Journals (Sweden)

    H Beyki

    2011-12-01

    Full Text Available The current study was conducted to investigate the effect of short-term divergent selection on the shape growth curve in different lines of Japanese quail. The Quail lines utilized in this study were two divergently selected for high (HW and low (LW 4-wk body weight during 7 generation and also a control line (C. The Richard function parameters were used to describe growth curves of different lines. The weight at hatch was approximately similar among lines (8.08 g, 7.55 g and 8.76 g for HW, LW and C line respectively. The results of current study indicated that the selected lines (HW & LW were immediately diverged from the C line after hatch. Sexes within each line had no difference in average growth rate, age and body weight at inflection point and adult body weight. However significant differences were found in the growth curve parameters among lines. The results of current study indicated that short term divergent selection for 4-wk BW in Japanese quail can change the growth pattern and the carcass compartments of the selected birds. Therefore to avoid undesirable side effects due to selection in Japanese quails it is recommended to consider the growth pattern changes of the selected birds in the breeding programs

  8. Dynamic Transcriptional Regulation of Fis in Salmonella During the Exponential Phase.

    Science.gov (United States)

    Wang, Hui; Wang, Lei; Li, Ping; Hu, Yilang; Zhang, Wei; Tang, Bo

    2015-12-01

    Fis is one of the most important global regulators and has attracted extensive research attention. Many studies have focused on comparing the Fis global regulatory networks for exploring Fis function during different growth stages, such as the exponential and stationary stages. Although the Fis protein in bacteria is mainly expressed in the exponential phase, the dynamic transcriptional regulation of Fis during the exponential phase remains poorly understood. To address this question, we used RNA-seq technology to identify the Fis-regulated genes in the S. enterica serovar Typhimurium during the early exponential phase, and qRT-PCR was performed to validate the transcriptional data. A total of 1495 Fis-regulated genes were successfully identified, including 987 Fis-repressed genes and 508 Fis-activated genes. Comparing the results of this study with those of our previous study, we found that the transcriptional regulation of Fis was diverse during the early- and mid-exponential phases. The results also showed that the strong positive regulation of Fis on Salmonella pathogenicity island genes in the mid-exponential phase transitioned into insignificant effect in the early exponential phase. To validate these results, we performed a cell infection assay and found that Δfis only exhibited a 1.49-fold decreased capacity compared with the LT2 wild-type strain, indicating a large difference from the 6.31-fold decrease observed in the mid-exponential phase. Our results provide strong evidence for a need to thoroughly understand the dynamic transcriptional regulation of Fis in Salmonella during the exponential phase.

  9. An exponential distribution

    International Nuclear Information System (INIS)

    Anon

    2009-01-01

    In this presentation author deals with the probabilistic evaluation of product life on the example of the exponential distribution. The exponential distribution is special one-parametric case of the weibull distribution.

  10. Existence of a common growth curve for silt-sized quartz OSL of loess from different continents

    International Nuclear Information System (INIS)

    Lai Zhongping; Brueckner, Helmut; Zoeller, Ludwig; Fuelling, Alexander

    2007-01-01

    Recent publications revealed different opinions regarding the existence of a common growth curve (CGC) for OSL of quartz. In the current study, 18 loess samples were collected from four continents (Asia, America, Africa, and Europe) in order to further examine this issue. Except the three samples from Chile in South America, 15 samples display similar dose-response curves up to a regeneration dose of 200 Gy using the SAR protocol, suggesting the existence of a global CGC for loess from different continents. For samples with equivalent doses (D e ) from ∼10 to ∼170Gy, the D e s determined by the CGC are in good agreement with the D e s by the SAR protocol. The Chilean samples posses a growth curve that differs from the CGC, showing much lower saturation doses. We suggest that it may be due to contamination with heavy minerals

  11. The exponential age distribution and the Pareto firm size distribution

    OpenAIRE

    Coad, Alex

    2008-01-01

    Recent work drawing on data for large and small firms has shown a Pareto distribution of firm size. We mix a Gibrat-type growth process among incumbents with an exponential distribution of firm’s age, to obtain the empirical Pareto distribution.

  12. On the analysis of Canadian Holstein dairy cow lactation curves using standard growth functions

    NARCIS (Netherlands)

    López, S.; France, J.; Odongo, N.E.; McBride, R.A.; Kebreab, E.; Alzahal, O.; McBride, B.W.; Dijkstra, J.

    2015-01-01

    Six classical growth functions (monomolecular, Schumacher, Gompertz, logistic, Richards, and Morgan) were fitted to individual and average (by parity) cumulative milk production curves of Canadian Holstein dairy cows. The data analyzed consisted of approximately 91,000 daily milk yield records

  13. Multivariate Matrix-Exponential Distributions

    DEFF Research Database (Denmark)

    Bladt, Mogens; Nielsen, Bo Friis

    2010-01-01

    be written as linear combinations of the elements in the exponential of a matrix. For this reason we shall refer to multivariate distributions with rational Laplace transform as multivariate matrix-exponential distributions (MVME). The marginal distributions of an MVME are univariate matrix......-exponential distributions. We prove a characterization that states that a distribution is an MVME distribution if and only if all non-negative, non-null linear combinations of the coordinates have a univariate matrix-exponential distribution. This theorem is analog to a well-known characterization theorem...

  14. Liver fibrosis: stretched exponential model outperforms mono-exponential and bi-exponential models of diffusion-weighted MRI.

    Science.gov (United States)

    Seo, Nieun; Chung, Yong Eun; Park, Yung Nyun; Kim, Eunju; Hwang, Jinwoo; Kim, Myeong-Jin

    2018-07-01

    To compare the ability of diffusion-weighted imaging (DWI) parameters acquired from three different models for the diagnosis of hepatic fibrosis (HF). Ninety-five patients underwent DWI using nine b values at 3 T magnetic resonance. The hepatic apparent diffusion coefficient (ADC) from a mono-exponential model, the true diffusion coefficient (D t ), pseudo-diffusion coefficient (D p ) and perfusion fraction (f) from a biexponential model, and the distributed diffusion coefficient (DDC) and intravoxel heterogeneity index (α) from a stretched exponential model were compared with the pathological HF stage. For the stretched exponential model, parameters were also obtained using a dataset of six b values (DDC # , α # ). The diagnostic performances of the parameters for HF staging were evaluated with Obuchowski measures and receiver operating characteristics (ROC) analysis. The measurement variability of DWI parameters was evaluated using the coefficient of variation (CoV). Diagnostic accuracy for HF staging was highest for DDC # (Obuchowski measures, 0.770 ± 0.03), and it was significantly higher than that of ADC (0.597 ± 0.05, p bi-exponential DWI model • Acquisition of six b values is sufficient to obtain accurate DDC and α.

  15. Growth curve of Atlantoscia floridana (van Name (Crustacea, Isopoda, Philosciidae from a Brazilian Restinga Forest

    Directory of Open Access Journals (Sweden)

    Paula Beatriz Araujo

    2004-03-01

    Full Text Available The terrestrial isopod Atlantoscia floridana (van Name, 1940 occurs from the U.S.A. (Florida to Brazil and Argentina. In the southernmost Brazilian State, Rio Grande do Sul, the species is recorded in many localities, in urban and in non-urban areas. The growth curve of Atlantoscia floridana based on field data is presented. The specimens were sampled from April, 2000 to October, 2001 at the Reserva Biológica do Lami (RBL, Rio Grande do Sul. Captured individuals were sexed and had their cephalothorax width measured, with the data analyzed with von Bertalanffy's model. The growth curves for males and females are described, respectively, by the equations: Wt = 1.303 [1 - e-0.00941 (t + 50.37] and Wt = 1.682 [1 - e-0.00575 (t + 59.13]. The curves showed differential growth between sexes, where females reach a higher Wµ with a slower growth rate. Based on the growth curves it was also possible to estimate life expectancy for males and females.O isópodo terrestre Atlantoscia floridana (van Name, 1940 ocorre desde os Estados Unidos (Flórida até o Brasil e Argentina. No Rio Grande do Sul a espécie é registrada em muitas localidades, em áreas urbanas e não-urbanas. Este trabalho apresenta a curva de crescimento de Atlantoscia floridana, baseada em dados de campo. Os espécimes foram amostrados desde abril, 2000 a outubro, 2001 na Reserva Biológica do Lami (RBL, Rio Grande do Sul. Os indivíduos capturados foram sexados e tiveram o cefalotórax medido. Os dados foram analisados utilizando-se o modelo de von Bertalanffy. A curva de crescimento para machos e fêmeas são descritas, respectivamente, pelas equações Wt = 1.303 [1 - e-0.00941 (t + 50.37] e Wt = 1.682 [1 - e -0.00575 (t + 59.13]. As curvas mostraram crescimento diferencial entre os sexos, onde as fêmeas atingem o maior Wµ com uma taxa de crescimento menor. Com base nas curvas de crescimento também foi possível estimar a expectativa de vida para machos e fêmeas.

  16. Using Calculus to Model the Growth of L. Plantarum Bacteria

    Directory of Open Access Journals (Sweden)

    Erin Carey

    2009-01-01

    Full Text Available Experimental data for the growth of Lactobacillus plantarum bacteria have been obtained over time, creating the need for mathematical means to model this data. We use the Gompertz model because it is a sigmoid function for a time series, where growth is slowest at the start and end of a time period. The Gompertz model is especially useful because it defines specific parameters that characterize the S-shaped curve. In addition, the Gompertz model uses relative growth, which is the logarithm of the given population compared to the initial population. This reflects the fact that bacteria grow exponentially. The important parameters that were found were the lag time and the asymptote.

  17. Rayleigh-Taylor instability under curved substrates: An optimal transient growth analysis

    Science.gov (United States)

    Balestra, Gioele; Brun, P.-T.; Gallaire, François

    2016-12-01

    We investigate the stability of thin viscous films coated on the inside of a horizontal cylindrical substrate. In such a case, gravity acts both as a stabilizing force through the progressive drainage of the film and as a destabilizing force prone to form droplets via the Rayleigh-Taylor instability. The drainage solution, derived from lubrication equations, is found asymptotically stable with respect to infinitesimally small perturbations, although in reality, droplets often form. To resolve this paradox, we perform an optimal transient growth analysis for the first-order perturbations of the liquid's interface, generalizing the results of Trinh et al. [Phys. Fluids 26, 051704 (2014), 10.1063/1.4876476]. We find that the system displays a linear transient growth potential that gives rise to two different scenarios depending on the value of the Bond number (prescribing the relative importance of gravity and surface tension forces). At low Bond numbers, the optimal perturbation of the interface does not generate droplets. In contrast, for higher Bond numbers, perturbations on the upper hemicircle yield gains large enough to potentially form droplets. The gain increases exponentially with the Bond number. In particular, depending on the amplitude of the initial perturbation, we find a critical Bond number above which the short-time linear growth is sufficient to trigger the nonlinear effects required to form dripping droplets. We conclude that the transition to droplets detaching from the substrate is noise and perturbation dependent.

  18. GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Wei Ming; Lee, Grace W.M. [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106 (China); Wu, Chih Cheng [Energy and Air Pollution Control Section, New Materials R and D Department, China Steel Corporation, 1, Chung-Kang Road, Siaogang District, Kaohsiung 81233 (China)

    2008-01-15

    The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced. (author)

  19. GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

    Energy Technology Data Exchange (ETDEWEB)

    Huang Weiming [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106, Taiwan (China); Lee, Grace W.M. [Graduate Institute of Environmental Engineering, National Taiwan University, 71, Chou-Shan Road, Taipei 106, Taiwan (China)], E-mail: gracelee@ntu.edu.tw; Wu Chihcheng [Energy and Air Pollution Control Section, New Materials R and D Department, China Steel Corporation, 1, Chung-Kang Road, Siaogang District, Kaohsiung 81233, Taiwan (China)

    2008-01-15

    The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced.

  20. GHG emissions, GDP growth and the Kyoto Protocol: A revisit of Environmental Kuznets Curve hypothesis

    International Nuclear Information System (INIS)

    Huang Weiming; Lee, Grace W.M.; Wu Chihcheng

    2008-01-01

    The Kyoto Protocol attempts through political negotiations to guide participating industrialized countries' greenhouse gas (GHG) emissions from a positive growing trend, to reach a peak point (or turning point), and then be reduced to a negative growth. That means the relationship between decreasing GHG emissions and economic growth may be described by an inverted-U curve (or called a bell-shaped curve), which is consistent with the concept of the Environmental Kuznets Curve (EKC) hypothesis. This research observed that the economic development and GHG emissions in Economies in Transition (EITs) exhibit a hockey-stick curve trend (or called quasi-L-shape curve), that also generates a lot of 'hot air' which is significant to the implementation of the Kyoto Protocol. In addition, through the analysis of single-country time series data and GDP data, this research demonstrated that statistical data for most of the Annex II countries do not possess evidence that supports the EKC hypothesis for GHG emissions. The results from this study also indicated that the 38 industrialized countries are unable to meet their targets under the Kyoto Protocol within the specified time period, which are probably caused by the econometric method's inability to predict accurately the extents and development of innovative technologies and Clean Development Mechanism (CDM) projects. If the international community truly wants to reduce the GHG emissions, the effectiveness of the existing international framework for emissions reduction needs to be reconsidered seriously, and the global cooperation mechanism also needs to be greatly enhanced

  1. First growth curves based on the World Health Organization reference in a Nationally-Representative Sample of Pediatric Population in the Middle East and North Africa (MENA): the CASPIAN-III study

    Science.gov (United States)

    2012-01-01

    Background The World Health Organization (WHO) is in the process of establishing a new global database on the growth of school children and adolescents. Limited national data exist from Asian children, notably those living in the Middle East and North Africa (MENA). This study aimed to generate the growth chart of a nationally representative sample of Iranian children aged 10–19 years, and to explore how well these anthropometric data match with international growth references. Methods In this nationwide study, the anthropometric data were recorded from Iranian students, aged 10–19 years, who were selected by multistage random cluster sampling from urban and rural areas. Prior to the analysis, outliers were excluded from the features height-for-age and body mass index (BMI)-for-age using the NCHS/WHO cut-offs. The Box-Cox power exponential (BCPE) method was used to calculate height-for-age and BMI-for-age Z-scores for our study participants. Then, children with overweight, obesity, thinness, and severe thinness were identified using the BMI-for-age z-scores. Moreover, stunted children were detected using the height-for-age z-scores. The growth curve of the Iranian children was then generated from the z-scores, smoothed by cubic S-plines. Results The study population comprised 5430 school students consisting of 2312 (44%) participants aged 10–14 years , and 3118 (58%) with 15–19 years of age. Eight percent of the participants had low BMI (thinness: 6% and severe thinness: 2%), 20% had high BMI (overweight: 14% and obesity: 6%), and 7% were stunted. The prevalence rates of low and high BMI were greater in boys than in girls (P growth curves generated from a national dataset may be included for establishing WHO global database on children’s growth. Similar to most low-and middle income populations, Iranian children aged 10–19 years are facing a double burden of weight disorders, notably under- and over- nutrition, which should be considered in

  2. Computerized glow curve deconvolution of thermoluminescent emission from polyminerals of Jamaica Mexican flower

    Science.gov (United States)

    Favalli, A.; Furetta, C.; Zaragoza, E. Cruz; Reyes, A.

    The aim of this work is to study the main thermoluminescence (TL) characteristics of the inorganic polyminerals extracted from dehydrated Jamaica flower or roselle (Hibiscus sabdariffa L.) belonging to Malvaceae family of Mexican origin. TL emission properties of the polymineral fraction in powder were studied using the initial rise (IR) method. The complex structure and kinetic parameters of the glow curves have been analysed accurately using the computerized glow curve deconvolution (CGCD) assuming an exponential distribution of trapping levels. The extension of the IR method to the case of a continuous and exponential distribution of traps is reported, such as the derivation of the TL glow curve deconvolution functions for continuous trap distribution. CGCD is performed both in the case of frequency factor, s, temperature independent, and in the case with the s function of temperature.

  3. Exponential Cardassian universe

    International Nuclear Information System (INIS)

    Liu Daojun; Sun Changbo; Li Xinzhou

    2006-01-01

    The expectation of explaining cosmological observations without requiring new energy sources is forsooth worthy of investigation. In this Letter, a new kind of Cardassian models, called exponential Cardassian models, for the late-time universe are investigated in the context of the spatially flat FRW universe scenario. We fit the exponential Cardassian models to current type Ia supernovae data and find they are consistent with the observations. Furthermore, we point out that the equation-of-state parameter for the effective dark fluid component in exponential Cardassian models can naturally cross the cosmological constant divide w=-1 that observations favor mildly without introducing exotic material that destroy the weak energy condition

  4. Breast meat quality of chickens with divergent growth rates and its relation to growth curve parameters

    Directory of Open Access Journals (Sweden)

    P. C. Muth

    2017-11-01

    Full Text Available The effects of the increase of body weight of contemporary broilers during growth on functional meat quality and color characteristics of the chicken breast muscle are controversially debated. Therefore, male chickens (n = 264 of a fast-growing commercial broiler (Ross 308 and two slow-growing experimental meat-type chicken lines were compared at equal age and at similar body weight in order to investigate the effect of growth rate on selected functional breast meat traits and meat color. Additionally, the breast meat characteristics of birds with different growth profiles were compared within lines. When the body weight of commercial broilers reached about 40 to 60 % of their growth potential, they exhibited particularly high ultimate pH values compared with slow-growing lines. The ability of the meat of fast-growing broilers to retain water during cooking was impaired (5 to 16 percentage points increased cooking loss compared to slow-growing lines, which, in contrast to pH, was only marginally affected by body weight and/or age at slaughter. No unfavorable correlations of breast meat quality traits with the growth profile, represented by growth curve parameters derived from the Gompertz–Laird equation, were detected within any of the investigated chicken lines. It is noteworthy that the associations of ultimate pH and cooking loss with maximum growth speed indicate a non-linear relationship. Thus, some of the functional characteristics of breast meat of the fast-growing broiler resembled the white-striping defect described for poultry meat, but the hypothesis that selection on increased growth rates is detrimental for meat quality per se could not be confirmed. In fact, an elevated growth potential in particular, i.e., body weight at maturity, could have some beneficial effects for the water-holding capacity of breast meat, regardless of the genotypic growth rate.

  5. Estimation of exponential convergence rate and exponential stability for neural networks with time-varying delay

    International Nuclear Information System (INIS)

    Tu Fenghua; Liao Xiaofeng

    2005-01-01

    We study the problem of estimating the exponential convergence rate and exponential stability for neural networks with time-varying delay. Some criteria for exponential stability are derived by using the linear matrix inequality (LMI) approach. They are less conservative than the existing ones. Some analytical methods are employed to investigate the bounds on the interconnection matrix and activation functions so that the systems are exponentially stable

  6. Bayesian Exponential Smoothing.

    OpenAIRE

    Forbes, C.S.; Snyder, R.D.; Shami, R.S.

    2000-01-01

    In this paper, a Bayesian version of the exponential smoothing method of forecasting is proposed. The approach is based on a state space model containing only a single source of error for each time interval. This model allows us to improve current practices surrounding exponential smoothing by providing both point predictions and measures of the uncertainty surrounding them.

  7. Continuous exponential martingales and BMO

    CERN Document Server

    Kazamaki, Norihiko

    1994-01-01

    In three chapters on Exponential Martingales, BMO-martingales, and Exponential of BMO, this book explains in detail the beautiful properties of continuous exponential martingales that play an essential role in various questions concerning the absolute continuity of probability laws of stochastic processes. The second and principal aim is to provide a full report on the exciting results on BMO in the theory of exponential martingales. The reader is assumed to be familiar with the general theory of continuous martingales.

  8. Enhancement of L-phenylalanine production by engineered Escherichia coli using phased exponential L-tyrosine feeding combined with nitrogen source optimization.

    Science.gov (United States)

    Yuan, Peipei; Cao, Weijia; Wang, Zhen; Chen, Kequan; Li, Yan; Ouyang, Pingkai

    2015-07-01

    Nitrogen source optimization combined with phased exponential L-tyrosine feeding was employed to enhance L-phenylalanine production by a tyrosine-auxotroph strain, Escherichia coli YP1617. The absence of (NH4)2SO4, the use of corn steep powder and yeast extract as composite organic nitrogen source were more suitable for cell growth and L-phenylalanine production. Moreover, the optimal initial L-tyrosine level was 0.3 g L(-1) and exponential L-tyrosine feeding slightly improved L-phenylalanine production. Nerveless, L-phenylalanine production was greatly enhanced by a strategy of phased exponential L-tyrosine feeding, where exponential feeding was started at the set specific growth rate of 0.08, 0.05, and 0.02 h(-1) after 12, 32, and 52 h, respectively. Compared with exponential L-tyrosine feeding at the set specific growth rate of 0.08 h(-1), the developed strategy obtained a 15.33% increase in L-phenylalanine production (L-phenylalanine of 56.20 g L(-1)) and a 45.28% decrease in L-tyrosine supplementation. Copyright © 2014 The Society for Biotechnology, Japan. Published by Elsevier B.V. All rights reserved.

  9. A longitudinal study of interethnic contacts in Germany: estimates from a multilevel growth curve model

    NARCIS (Netherlands)

    Martinovic, B.; van Tubergen, F.; Maas, I.

    2015-01-01

    Interethnic ties are considered important for the cohesion in society. Previous research has studied the determinants of interethnic ties with cross-sectional data or lagged panel designs. This study improves on prior research by applying multilevel growth curve modelling techniques with lagged

  10. A longitudinal study of interethnic contacts in Germany : Estimates from a multilevel growth curve model

    NARCIS (Netherlands)

    Martinovic, Borja|info:eu-repo/dai/nl/304822752; van Tubergen, Frank|info:eu-repo/dai/nl/271429534; Maas, Ineke|info:eu-repo/dai/nl/075229390

    2015-01-01

    Interethnic ties are considered important for the cohesion in society. Previous research has studied the determinants of interethnic ties with cross-sectional data or lagged panel designs. This study improves on prior research by applying multilevel growth curve modelling techniques with lagged

  11. Developments in Interpreting Learning Curves and Applications to Energy Technology Policy

    International Nuclear Information System (INIS)

    Van der Zwaan, B.C.C.; Wene, C.O.

    2011-01-01

    The book 'Learning Curves: Theory, Models, and Applications' first draws a learning map that shows where learning is involved within organizations, then examines how it can be sustained, perfected, and accelerated. The book reviews empirical findings in the literature in terms of different sources for learning and partial assessments of the steps that make up the actual learning process inside the learning curve. Chapter 23 on 'Developments in Interpreting Learning Curves and Applications to Energy Technology Policy' is written by Bob van der Zwaan and Clas-Otto Wene. In this chapter they provide some interpretations of experience and learning curves starting from three different theoretical platforms. These interpretations are aimed at explaining learning rates for different energy technologies. The ultimate purpose is to find the role that experience and learning curves can legitimately play in designing efficient government deployment programs and in analyzing the implications of different energy scenarios. The 'Component Learning' section summarizes recent work by the authors that focuses on the disaggregation of technologies in their respective components and argues that traditional learning for overall technology should perhaps be replaced by a phenomenology that recognizes learning for individual components. The 'Learning and Time' section presents an approach that departs more strongly from the conventional learning curve methodology, by suggesting that exponential growth and progress may be the deeper underlying processes behind observed learning-by-doing. Contrary to this view, the cybernetic approach presented in the 'Cybernetic Approach' section sees learning curves as expressing a fundamental property of organizations in competitive markets and applies the findings from second order cybernetics to calculate the learning rates for operationally closed systems. All three interpretations find empirical support. The 'Conclusions' section summarizes the

  12. Developments in Interpreting Learning Curves and Applications to Energy Technology Policy

    Energy Technology Data Exchange (ETDEWEB)

    Van der Zwaan, B.C.C. [Energy research Centre of the Netherlands, ECN Policy Studies, Petten (Netherlands); Wene, C.O. [Wenergy, Lund (Sweden)

    2011-06-15

    The book 'Learning Curves: Theory, Models, and Applications' first draws a learning map that shows where learning is involved within organizations, then examines how it can be sustained, perfected, and accelerated. The book reviews empirical findings in the literature in terms of different sources for learning and partial assessments of the steps that make up the actual learning process inside the learning curve. Chapter 23 on 'Developments in Interpreting Learning Curves and Applications to Energy Technology Policy' is written by Bob van der Zwaan and Clas-Otto Wene. In this chapter they provide some interpretations of experience and learning curves starting from three different theoretical platforms. These interpretations are aimed at explaining learning rates for different energy technologies. The ultimate purpose is to find the role that experience and learning curves can legitimately play in designing efficient government deployment programs and in analyzing the implications of different energy scenarios. The 'Component Learning' section summarizes recent work by the authors that focuses on the disaggregation of technologies in their respective components and argues that traditional learning for overall technology should perhaps be replaced by a phenomenology that recognizes learning for individual components. The 'Learning and Time' section presents an approach that departs more strongly from the conventional learning curve methodology, by suggesting that exponential growth and progress may be the deeper underlying processes behind observed learning-by-doing. Contrary to this view, the cybernetic approach presented in the 'Cybernetic Approach' section sees learning curves as expressing a fundamental property of organizations in competitive markets and applies the findings from second order cybernetics to calculate the learning rates for operationally closed systems. All three interpretations find empirical

  13. Curve-of-growth analysis of a red giant in the globular cluster M13

    International Nuclear Information System (INIS)

    Griffin, R.

    1979-01-01

    A coude spectrogram of a red giant (L973) in the globular cluster M13 is analysed, with respect to α Boo, by the differential curve-of-growth technique. The overall metal abundance is found to be approximately one-tenth of that of α Boo, or one-fortieth that of the Sun. (author)

  14. Economic growth and emissions reconsidering the empirical basis of environmental Kuznets curves

    International Nuclear Information System (INIS)

    De Bruyn, S.M.; Van den Bergh, J.C.J.M.; Opschoor, J.B.

    1998-01-01

    Recent empirical research indicates that certain types of emissions follow an inverted-U or environmental Kuznets curve (EKC) as income grows. This regularity has been interpreted as a possible de-linking of economic growth and patterns of certain pollutants for developed economies. In this paper the empirical basis of this result is investigated, by considering some statistical particularities of the various EKC studies performed. It is argued that the inverted-U relationship between income and emissions estimated from panel data need not hold for specific individual countries over time. Based on insights from 'intensity-of-use' analysis in resource economics an alternative growth model is specified and estimated for three types of emissions (CO 2 , NO x and SO 2 ) in four countries (Netherlands, UK, USA and Western Germany). It is found that the time patterns of these emissions correlate positively with economic growth and that emission reductions may have been achieved as a result of structural and technological changes in the economy. 'Sustainable growth' is defined as the rate of economic growth that does not lead to growth in emissions. Its rate is calculated for each type of emission and country, based on estimated parameter values. The resulting indicators reflect a balance between the positive influence of growth and negative influence of structural change and technological progress on emission levels

  15. Exponential critical-state model for magnetization of hard superconductors

    International Nuclear Information System (INIS)

    Chen, D.; Sanchez, A.; Munoz, J.S.

    1990-01-01

    We have calculated the initial magnetization curves and hysteresis loops for hard type-II superconductors based on the exponential-law model, J c (H i ) =k exp(-|H i |/H 0 ), where k and H 0 are constants. After discussing the general behavior of penetrated supercurrents in an infinitely long column specimen, we define a general cross-sectional shape based on two equal circles of radius a, which can be rendered into a circle, a rectangle, or many other shapes. With increasing parameter p (=ka/H 0 ), the computed M-H curves show obvious differences with those computed from Kim's model and approach the results of a simple infinitely narrow square pulse J c (H i ). For high-T c superconductors, our results can be applied to the study of the magnetic properties and the critical-current density of single crystals, as well as to the determination of the intergranular critical-current density from magnetic measurements

  16. Dynamics of exponential maps

    OpenAIRE

    Rempe, Lasse

    2003-01-01

    This thesis contains several new results about the dynamics of exponential maps $z\\mapsto \\exp(z)+\\kappa$. In particular, we prove that periodic external rays of exponential maps with nonescaping singular value always land. This is an analog of a theorem of Douady and Hubbard for polynomials. We also answer a question of Herman, Baker and Rippon by showing that the boundary of an unbounded exponential Siegel disk always contains the singular value. In addition to the presentation of new resul...

  17. An introduction to latent variable growth curve modeling concepts, issues, and application

    CERN Document Server

    Duncan, Terry E; Strycker, Lisa A

    2013-01-01

    This book provides a comprehensive introduction to latent variable growth curve modeling (LGM) for analyzing repeated measures. It presents the statistical basis for LGM and its various methodological extensions, including a number of practical examples of its use. It is designed to take advantage of the reader's familiarity with analysis of variance and structural equation modeling (SEM) in introducing LGM techniques. Sample data, syntax, input and output, are provided for EQS, Amos, LISREL, and Mplus on the book's CD. Throughout the book, the authors present a variety of LGM techniques that are useful for many different research designs, and numerous figures provide helpful diagrams of the examples.Updated throughout, the second edition features three new chapters-growth modeling with ordered categorical variables, growth mixture modeling, and pooled interrupted time series LGM approaches. Following a new organization, the book now covers the development of the LGM, followed by chapters on multiple-group is...

  18. Quantification of antibiotic drug potency by a two-compartment radioassay of bacterial growth

    International Nuclear Information System (INIS)

    Boonkitticharoen, V.; Ehrhardt, J.C.; Kirchner, P.T.

    1990-01-01

    The two-compartment radioassay for microbial kinetics based on continuous measurement of the 14 CO 2 released by bacterial metabolism of 14C-labeled substrate offers a valuable approach to testing the potency of antimicrobial drugs. By using a previously validated radioassay with gram-positive and gram-negative bacteria, a group of protein synthesis inhibitors was evaluated for their effect on microbial growth kinetics. All tested drugs induced changes in both the slopes and intercepts of the growth curves. An exponential growth model was applied to quantify the drug effect on the processes of bacterial 14 CO 2 liberation and cell generation. The response was measured in terms of a generation rate constant. A linear dependence of the generation rate constant on the dose of spectinomycin was observed with Escherichia coli. Sigmoidal-shaped curves were found in the assays of chloramphenicol and tetracycline. The implications of dose-response curves are discussed on the basis of the receptor site concept for drug action. The assay sensitivities for chloramphenicol and tetracycline were similar to those obtained by the cell counting method, but the sensitivity of the radioassay was at least 10 times greater for spectinomycin

  19. Stretched exponential distributions in nature and economy: ``fat tails'' with characteristic scales

    Science.gov (United States)

    Laherrère, J.; Sornette, D.

    1998-04-01

    To account quantitatively for many reported "natural" fat tail distributions in Nature and Economy, we propose the stretched exponential family as a complement to the often used power law distributions. It has many advantages, among which to be economical with only two adjustable parameters with clear physical interpretation. Furthermore, it derives from a simple and generic mechanism in terms of multiplicative processes. We show that stretched exponentials describe very well the distributions of radio and light emissions from galaxies, of US GOM OCS oilfield reserve sizes, of World, US and French agglomeration sizes, of country population sizes, of daily Forex US-Mark and Franc-Mark price variations, of Vostok (near the south pole) temperature variations over the last 400 000 years, of the Raup-Sepkoski's kill curve and of citations of the most cited physicists in the world. We also discuss its potential for the distribution of earthquake sizes and fault displacements. We suggest physical interpretations of the parameters and provide a short toolkit of the statistical properties of the stretched exponentials. We also provide a comparison with other distributions, such as the shifted linear fractal, the log-normal and the recently introduced parabolic fractal distributions.

  20. Weight-for-length/height growth curves for children and adolescents in China in comparison with body mass index in prevalence estimates of malnutrition.

    Science.gov (United States)

    Zong, Xinnan; Li, Hui; Zhang, Yaqin; Wu, Huahong

    2017-05-01

    It is important to update weight-for-length/height growth curves in China and re-examine their performance in screening malnutrition. To develop weight-for-length/height growth curves for Chinese children and adolescents. A total of 94 302 children aged 0-19 years with complete sex, age, weight and length/height data were obtained from two cross-sectional large-scaled national surveys in China. Weight-for-length/height growth curves were constructed using the LMS method before and after average spermarcheal/menarcheal ages, respectively. Screening performance in prevalence estimates of wasting, overweight and obesity was compared between weight-for-height and body mass index (BMI) criteria based on a test population of 21 416 children aged 3-18. The smoothed weight-for-length percentiles and Z-scores growth curves with length 46-110 cm for both sexes and weight-for-height with height 70-180 cm for boys and 70-170 cm for girls were established. The weight-for-height and BMI-for-age had strong correlation in screening wasting, overweight and obesity in each age-sex group. There was no striking difference in prevalence estimates of wasting, overweight and obesity between two indicators except for obesity prevalence at ages 6-11. This set of smoothed weight-for-length/height growth curves may be useful in assessing nutritional status from infants to post-pubertal adolescents.

  1. Survival curves study of platelet labelling with 51Cr

    International Nuclear Information System (INIS)

    Penas, M.E.

    1981-01-01

    Platelet kinetics and idiopathic thrombocytopenic purpura were researched in the literature. An 'in vitro' platelet labelling with 51 Cr procedure in implementation has been evaluated in human beings. Functions used for fitting considered the cases whether the curve was linear or exponential as well as the presence of hematies. (author)

  2. Long-wave theory for a new convective instability with exponential growth normal to the wall.

    Science.gov (United States)

    Healey, J J

    2005-05-15

    A linear stability theory is presented for the boundary-layer flow produced by an infinite disc rotating at constant angular velocity in otherwise undisturbed fluid. The theory is developed in the limit of long waves and when the effects of viscosity on the waves can be neglected. This is the parameter regime recently identified by the author in a numerical stability investigation where a curious new type of instability was found in which disturbances propagate and grow exponentially in the direction normal to the disc, (i.e. the growth takes place in a region of zero mean shear). The theory describes the mechanisms controlling the instability, the role and location of critical points, and presents a saddle-point analysis describing the large-time evolution of a wave packet in frames of reference moving normal to the disc. The theory also shows that the previously obtained numerical solutions for numerically large wavelengths do indeed lie in the asymptotic long-wave regime, and so the behaviour and mechanisms described here may apply to a number of cross-flow instability problems.

  3. SERIAL ULTRASOUND TO ESTIMATE FETAL GROWTH CURVES IN SOUTHERN TAMANDUA (TAMANDUA TETRADACTYLA).

    Science.gov (United States)

    Thompson, Rachel; Wolf, Tiffany M; Robertson, Heather; Colburn, Margarita Woc; Moreno, Alexis; Moresco, Anneke; Napier, Anne Elise; Nofs, Sally A

    2017-06-01

    From 2012 to 2015, 16 pregnancies were monitored by ultrasonography in nine tamanduas ( Tamandua tetradactyla ) housed in three zoological facilities. Sonographic measurements were recorded to establish fetal growth curves using thoracic and skull landmarks described for giant anteaters ( Myrmecophaga tridactyla ). All pregnancies resulted in the uncomplicated delivery of healthy offspring, thus gestational development was considered normal. These data may be used as a reference for normal fetal development with potential for estimating parturition date in the absence of breeding data.

  4. Anthropometric evaluation of indigenous Brazilian children under 60 months of age using NCHS/1977 and WHO/2005 growth curves.

    Science.gov (United States)

    Orellana, Jesem D Y; Santos, Ricardo V; Coimbra, Carlos E A; Leite, Maurício S

    2009-01-01

    To perform a comparative analysis of anthropometric data from Suruí, Xavánte and Wari' indigenous children under 60 months of age using the NCHS/1977 and the WHO/2005 growth curves. Anthropometric measurements followed standard procedures and the data obtained were converted into z scores using the Epi-Info (Version 3.4) and WHO-Anthro (Version Beta) softwares. The indices height/age (H/A), weight/age (W/A) and weight/height (W/H) were descriptors of nutritional status for all children under 60 months of age, as well as the body mass index (BMI) for children 24-59 months old. The frequencies of Suruí children Wari' 61.7 and 68.3%. The frequencies of Suruí children Wari' 51.7 and 45.0%. None of the Suruí children were Wari' 1.7 and 0.0%. The frequencies of Suruí children > 2 z scores for W/H were 3.9 (NCHS/1977) and 3.9% (WHO/2005); Xavánte 0.0 and 0.8%; Wari' 0.0 and 0.0%. The frequency of Suruí children aged 24-59 months > 2 z scores for BMI was 5.4% (WHO/2005); Xavánte 9.5%; and Wari' 0.0%. Our findings revealed important differences in the results from nutritional assessment, according to the set of growth curves used; however, the use of both growth curves revealed a high prevalence of malnutrition. Therefore, future studies with indigenous populations should present their results using two sets of growth curves to allow consistent comparison.

  5. Time until initiation of tumor growth is an effective measure of the anti-angiogenic effect of TNP-470 on human glioblastoma in nude mice

    DEFF Research Database (Denmark)

    Kragh, M; Spang-Thomsen, M; Kristjansen, P E

    1999-01-01

    , 11, or 15 days after inoculation. The time from inoculation until initiation of exponential tumor growth was determined along with the post-therapeutic growth delay and the initial tumor doubling time (TD) for each individual tumor (n=103) on the basis of tumor volume growth curves. We found that: i......) the onset of growth of U87 xenografts was effectively inhibited by concurrent treatment with TNP-470 beyond the first three days after inoculation, ii) this effect was fully reversible upon termination of therapy, and iii) the post-therapeutic growth delay was independent of the accumulated dose...

  6. Parent involvement and science achievement: A latent growth curve analysis

    Science.gov (United States)

    Johnson, Ursula Yvette

    This study examined science achievement growth across elementary and middle school and parent school involvement using the Early Childhood Longitudinal Study - Kindergarten Class of 1998--1999 (ECLS-K). The ECLS-K is a nationally representative kindergarten cohort of students from public and private schools who attended full-day or half-day kindergarten class in 1998--1999. The present study's sample (N = 8,070) was based on students that had a sampling weight available from the public-use data file. Students were assessed in science achievement at third, fifth, and eighth grades and parents of the students were surveyed at the same time points. Analyses using latent growth curve modeling with time invariant and varying covariates in an SEM framework revealed a positive relationship between science achievement and parent involvement at eighth grade. Furthermore, there were gender and racial/ethnic differences in parents' school involvement as a predictor of science achievement. Findings indicated that students with lower initial science achievement scores had a faster rate of growth across time. The achievement gap between low and high achievers in earth, space and life sciences lessened from elementary to middle school. Parents' involvement with school usually tapers off after elementary school, but due to parent school involvement being a significant predictor of eighth grade science achievement, later school involvement may need to be supported and better implemented in secondary schooling.

  7. First growth curves based on the World Health Organization reference in a Nationally-Representative Sample of Pediatric Population in the Middle East and North Africa (MENA): the CASPIAN-III study.

    Science.gov (United States)

    Mansourian, Marjan; Marateb, Hamid Reza; Kelishadi, Roya; Motlagh, Mohammad Esmaeil; Aminaee, Tahereh; Taslimi, Mahnaz; Majdzadeh, Reza; Heshmat, Ramin; Ardalan, Gelayol; Poursafa, Parinaz

    2012-09-17

    The World Health Organization (WHO) is in the process of establishing a new global database on the growth of school children and adolescents. Limited national data exist from Asian children, notably those living in the Middle East and North Africa (MENA). This study aimed to generate the growth chart of a nationally representative sample of Iranian children aged 10-19 years, and to explore how well these anthropometric data match with international growth references. In this nationwide study, the anthropometric data were recorded from Iranian students, aged 10-19 years, who were selected by multistage random cluster sampling from urban and rural areas. Prior to the analysis, outliers were excluded from the features height-for-age and body mass index (BMI)-for-age using the NCHS/WHO cut-offs. The Box-Cox power exponential (BCPE) method was used to calculate height-for-age and BMI-for-age Z-scores for our study participants. Then, children with overweight, obesity, thinness, and severe thinness were identified using the BMI-for-age z-scores. Moreover, stunted children were detected using the height-for-age z-scores. The growth curve of the Iranian children was then generated from the z-scores, smoothed by cubic S-plines. The study population comprised 5430 school students consisting of 2312 (44%) participants aged 10-14 years , and 3118 (58%) with 15-19 years of age. Eight percent of the participants had low BMI (thinness: 6% and severe thinness: 2%), 20% had high BMI (overweight: 14% and obesity: 6%), and 7% were stunted. The prevalence rates of low and high BMI were greater in boys than in girls (P < 0.001). The mean BMI-for-age, and the average height-for-age of Iranian children aged 10-19 years were lower than the WHO 2007 and United states Centers for Disease Control and Prevention 2000 (USCDC2000) references. The current growth curves generated from a national dataset may be included for establishing WHO global database on children's growth. Similar to most low

  8. First growth curves based on the World Health Organization reference in a Nationally-Representative Sample of Pediatric Population in the Middle East and North Africa (MENA: the CASPIAN-III study

    Directory of Open Access Journals (Sweden)

    Mansourian Marjan

    2012-09-01

    Full Text Available Abstract Background The World Health Organization (WHO is in the process of establishing a new global database on the growth of school children and adolescents. Limited national data exist from Asian children, notably those living in the Middle East and North Africa (MENA. This study aimed to generate the growth chart of a nationally representative sample of Iranian children aged 10–19 years, and to explore how well these anthropometric data match with international growth references. Methods In this nationwide study, the anthropometric data were recorded from Iranian students, aged 10–19 years, who were selected by multistage random cluster sampling from urban and rural areas. Prior to the analysis, outliers were excluded from the features height-for-age and body mass index (BMI-for-age using the NCHS/WHO cut-offs. The Box-Cox power exponential (BCPE method was used to calculate height-for-age and BMI-for-age Z-scores for our study participants. Then, children with overweight, obesity, thinness, and severe thinness were identified using the BMI-for-age z-scores. Moreover, stunted children were detected using the height-for-age z-scores. The growth curve of the Iranian children was then generated from the z-scores, smoothed by cubic S-plines. Results The study population comprised 5430 school students consisting of 2312 (44% participants aged 10–14 years , and 3118 (58% with 15–19 years of age. Eight percent of the participants had low BMI (thinness: 6% and severe thinness: 2%, 20% had high BMI (overweight: 14% and obesity: 6%, and 7% were stunted. The prevalence rates of low and high BMI were greater in boys than in girls (P  Conclusions The current growth curves generated from a national dataset may be included for establishing WHO global database on children’s growth. Similar to most low-and middle income populations, Iranian children aged 10–19 years are facing a double burden of weight disorders, notably under- and

  9. Self-Regulation and Recall: Growth Curve Modeling of Intervention Outcomes for Older Adults

    OpenAIRE

    West, Robin L.; Hastings, Erin C.

    2011-01-01

    Memory training has often been supported as a potential means to improve performance for older adults. Less often studied are the characteristics of trainees that benefit most from training. Using a self-regulatory perspective, the current project examined a latent growth curve model to predict training-related gains for middle-aged and older adult trainees from individual differences (e.g., education), information processing skills (strategy use) and self-regulatory factors such as self-effi...

  10. Bubble number saturation curve and asymptotics of hypobaric and hyperbaric exposures.

    Science.gov (United States)

    Wienke, B R

    1991-12-01

    Within bubble number limits of the varying permeability and reduced gradient bubble models, it is shown that a linear form of the saturation curve for hyperbaric exposures and a nearly constant decompression ratio for hypobaric exposures are simultaneously recovered from the phase volume constraint. Both limits are maintained within a single bubble number saturation curve. A bubble term, varying exponentially with inverse pressure, provides closure. Two constants describe the saturation curve, both linked to seed numbers. Limits of other decompression models are also discussed and contrasted for completeness. It is suggested that the bubble number saturation curve thus provides a consistent link between hypobaric and hyperbaric data, a link not established by earlier decompression models.

  11. Curva de crescimento de frutos de pêssego em regiões subtropicais Growth curve of peach fruits in subtropical enviroment

    Directory of Open Access Journals (Sweden)

    Emilio Dela Bruna

    2007-01-01

    to improve the fruit quality. The correct time for fruit pruning can be defined through the knowledge of the curve of fruit growth. Fruit growth, fresh weight (PV and dry weight (PS of 20 peach varieties had been evaluated at Epagri's Agriculture Research Station of Urussanga, State of Santa Catarina, Brazil (latitude 28º31'S, altitude 48 m. The plants had been grouped in varieties of short, medium and long cycle, related to the period from budding to fruit harvest, ranging from W77 to 85 days, 86 to 109 days and more than 109 days, respectively. Weekly, from blossom to harvest, green fruits have been harvested, then weighed (PV and dehydrated in a stove at 70ºC to determine the PS. All the varieties had presented a very high initial relative growth (PS daily gain / PS total of the fruit, which was reducing until the maturation of the fruits for the varieties of short and medium cycle. However, the long cycle varieties had an increase on the relative growth in the end of the cycle. Long cycle varieties presented three stages of fruit growth, considering the PS, PV and the daily accumulation of PS and PV: Stage I, with exponential growth; Stage II, with little growth; Stage III, with exponential growth culminating with the fruit maturation. On the other hand, varieties of medium and short cycle had not presented the Stage II, with little growth, switching directly from Stage I to Stage III.

  12. The Growth Path of Agricultural Labor Productivity in China: A Latent Growth Curve Model at the Prefectural Level

    Directory of Open Access Journals (Sweden)

    Peng Bin

    2016-06-01

    Full Text Available Given the shrinking proportion of agriculture output and the growing mobility of the labor force in China, how agricultural labor productivity develops has become an increasingly attractive topic for researchers and policy makers. This study aims to depict the development trajectory of agricultural labor productivity in China after its WTO entry. Based on a balanced panel data containing 287 Chinese prefectures from 2000 to 2013, this study applies the Latent Growth Curve Model (LGCM and finds that the agricultural labor productivity follows a piecewise growth path with two breaking points in the years of 2004 and 2009. This may stem from some exogenous stimulus, such as supporting policies launched in the breaking years. Further statistical analysis shows an expanding gap of agricultural labor productivity among different Chinese prefectures.

  13. Generalized approach to non-exponential relaxation

    Indian Academy of Sciences (India)

    Non-exponential relaxation is a universal feature of systems as diverse as glasses, spin ... which changes from a simple exponential to a stretched exponential and a power law by increasing the constraints in the system. ... Current Issue

  14. Recognizing Physisorption and Chemisorption in Carbon Nanotubes Gas Sensors by Double Exponential Fitting of the Response.

    Science.gov (United States)

    Calvi, Andrea; Ferrari, Alberto; Sbuelz, Luca; Goldoni, Andrea; Modesti, Silvio

    2016-05-19

    Multi-walled carbon nanotubes (CNTs) have been grown in situ on a SiO 2 substrate and used as gas sensors. For this purpose, the voltage response of the CNTs as a function of time has been used to detect H 2 and CO 2 at various concentrations by supplying a constant current to the system. The analysis of both adsorptions and desorptions curves has revealed two different exponential behaviours for each curve. The study of the characteristic times, obtained from the fitting of the data, has allowed us to identify separately chemisorption and physisorption processes on the CNTs.

  15. Lagrange α-exponential stability and α-exponential convergence for fractional-order complex-valued neural networks.

    Science.gov (United States)

    Jian, Jigui; Wan, Peng

    2017-07-01

    This paper deals with the problem on Lagrange α-exponential stability and α-exponential convergence for a class of fractional-order complex-valued neural networks. To this end, some new fractional-order differential inequalities are established, which improve and generalize previously known criteria. By using the new inequalities and coupling with the Lyapunov method, some effective criteria are derived to guarantee Lagrange α-exponential stability and α-exponential convergence of the addressed network. Moreover, the framework of the α-exponential convergence ball is also given, where the convergence rate is related to the parameters and the order of differential of the system. These results here, which the existence and uniqueness of the equilibrium points need not to be considered, generalize and improve the earlier publications and can be applied to monostable and multistable fractional-order complex-valued neural networks. Finally, one example with numerical simulations is given to show the effectiveness of the obtained results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  16. Economic growth and CO2 emissions in Malaysia: A cointegration analysis of the Environmental Kuznets Curve

    International Nuclear Information System (INIS)

    Saboori, Behnaz; Sulaiman, Jamalludin; Mohd, Saidatulakmal

    2012-01-01

    This paper attempts to establish a long-run as well as causal relationship between economic growth and carbon dioxide (CO 2 ) emissions for Malaysia. Using data for the years from 1980 to 2009, the Environmental Kuznets Curve (EKC) hypothesis was tested utilizing the Auto Regressive Distributed Lag (ARDL) methodology. The empirical results suggest the existence of a long-run relationship between per capita CO 2 emissions and real per capita Gross Domestic Product (GDP) when the CO 2 emissions level is the dependent variable. We found an inverted-U shape relationship between CO 2 emissions and GDP in both short and long-run, thus supporting the EKC hypothesis. The Granger Causality test based on the Vector Error Correction Model (VECM) presents an absence of causality between CO 2 emissions and economic growth in the short-run while demonstrating uni-directional causality from economic growth to CO 2 emissions in the long-run. - Highlights: ► We tested the dynamic relationship between economic growth and CO 2 emissions. ► The Environmental Kuznets Curve hypothesis was tested using bounds testing approach. ► The empirical analysis confirms the existence of EKC for Malaysia. ► Causality results in an absence of causality between CO 2 and income in the short-run. ► There is uni-directional causality from income to CO 2 emissions in the long-run.

  17. The exponentiated generalized Pareto distribution | Adeyemi | Ife ...

    African Journals Online (AJOL)

    Recently Gupta et al. (1998) introduced the exponentiated exponential distribution as a generalization of the standard exponential distribution. In this paper, we introduce a three-parameter generalized Pareto distribution, the exponentiated generalized Pareto distribution (EGP). We present a comprehensive treatment of the ...

  18. Transient disturbance growth in flows over convex surfaces

    Science.gov (United States)

    Karp, Michael; Hack, M. J. Philipp

    2017-11-01

    Flows over curved surfaces occur in a wide range of applications including airfoils, compressor and turbine vanes as well as aerial, naval and ground vehicles. In most of these applications the surface has convex curvature, while concave surfaces are less common. Since monotonic boundary-layer flows over convex surfaces are exponentially stable, they have received considerably less attention than flows over concave walls which are destabilized by centrifugal forces. Non-modal mechanisms may nonetheless enable significant disturbance growth which can make the flow susceptible to secondary instabilities. A parametric investigation of the transient growth and secondary instability of flows over convex surfaces is performed. The specific conditions yielding the maximal transient growth and strongest instability are identified. The effect of wall-normal and spanwise inflection points on the instability process is discussed. Finally, the role and significance of additional parameters, such as the geometry and pressure gradient, is analyzed.

  19. A novel microculture kinetic assay (MiCK assay) for malignant cell growth and chemosensitivity.

    Science.gov (United States)

    Kravtsov, V D

    1994-01-01

    The THERMOmax microplate reader was adapted for monitoring the growth kinetics of human leukaemic OCI/AML-2 and mouse tumour J-774.1 cell lines in continuous culture. Fluid evaporation from wells, CO2 escape and contamination were prevented by hermetic sealing of the microcultures in wells of a 96-well microplate, thus enabling the cells to grow exponentially for 72 h under the conditions of the incubated microplate reader. For both OCI/AML-2 cells, which grow in suspension, and adherent J-774.1 cells, a linear correlation was demonstrated between the number of unstained cells seeded in a given microplate well and the optical density (OD) of that well. Therefore, the OD/time curve of the culture could be deemed to be its growth curve. By the use of the linear fit equation, the actual number of the cells in the wells was computable at any time point of the assay. In the chemosensitivity test, an inhibitory effect of ARA-C on the growth of the cells could be estimated by viewing of the growth curves plotted on the screen. The maximum kinetic rates (Vmax) of the curves in the control and the ARA-C-treated wells were compared, yielding a growth inhibition index (GII). Comparison of results of the kinetic chemosensitivity assay with those of a [3H]thymidine incorporation assay revealed that the novel assay is suitable for precise quantitation of the cell chemosensitivity, is more informative and has the added technical advantage of performance without recourse to radioactive or chemically hazardous substances.

  20. Hyperbolic Cosine–Exponentiated Exponential Lifetime Distribution and its Application in Reliability

    Directory of Open Access Journals (Sweden)

    Omid Kharazmi

    2017-02-01

    Full Text Available Recently, Kharazmi and Saadatinik (2016 introduced a new family of lifetime distributions called hyperbolic cosine – F (HCF distribution. In the present paper, it is focused on a special case of HCF family with exponentiated exponential distribution as a baseline distribution (HCEE. Various properties of the proposed distribution including explicit expressions for the moments, quantiles, mode, moment generating function, failure rate function, mean residual lifetime, order statistics and expression of the entropy are derived. Estimating parameters of HCEE distribution are obtained by eight estimation methods: maximum likelihood, Bayesian, maximum product of spacings, parametric bootstrap, non-parametric bootstrap, percentile, least-squares and weighted least-squares. A simulation study is conducted to examine the bias, mean square error of the maximum likelihood estimators. Finally, one real data set has been analyzed for illustrative purposes and it is observed that the proposed model fits better than Weibull, gamma and generalized exponential distributions.

  1. Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histograms

    NARCIS (Netherlands)

    Bezemer, Rick; Faber, Dirk J.; Almac, Emre; Kalkman, Jeroen; Legrand, Matthieu; Heger, Michal; Ince, Can

    2010-01-01

    Although it is generally accepted that oxygen-quenched phosphorescence decay traces can be analyzed using the exponential series method (ESM), its application until now has been limited to a few (patho)physiological studies, probably because the reliability of the recovered oxygen tension (pO(2))

  2. An exponential material model for prediction of the flow curves of several AZ series magnesium alloys in tension and compression

    International Nuclear Information System (INIS)

    Fereshteh-Saniee, F.; Barati, F.; Badnava, H.; Fallah Nejad, Kh.

    2012-01-01

    Highlights: ► The exponential model can represent flow behaviors of AZ series Mg alloys very well. ► Strain rate sensitivities of AZ series Mg alloys in compression are nearly the same. ► Effect of zinc element on tensile activation energy is higher than on compressive one. ► Activation energies of AZ80 and AZ81 in tension were greater than in compression. ► Tensile and compressive rate sensitivities of AZ80 are not close to each other. -- Abstract: This paper is concerned with flow behaviors of several magnesium alloys, such as AZ31, AZ80 and AZ81, in tension and compression. The experiments were performed at elevated temperatures and for various strain rates. In order to eliminate the effect of inhomogeneous deformation in tensile and compression tests, the Bridgeman’s and numerical correction factors were respectively employed. A two-section exponential mathematical model was also utilized for prediction of flow stresses of different magnesium alloys in tension and compression. Moreover, based on the compressive flow model proposed, the peak stress and the relevant true strain could be estimated. The true stress and strain of the necking point can also be predicted using the corresponding relations. It was found that the flow behaviors estimated by the exponential flow model were encouragingly in very good agreement with experimental findings.

  3. An allometric scaling relation based on logistic growth of cities

    International Nuclear Information System (INIS)

    Chen, Yanguang

    2014-01-01

    Highlights: • An allometric scaling based on logistic process can be used to model urban growth. • The traditional allometry is based on exponential growth instead of logistic growth. • The exponential allometry represents a local scaling of urban growth. • The logistic allometry represents a global scaling of urban growth. • The exponential allometry is an approximation relation of the logistic allometry. - Abstract: The relationships between urban area and population size have been empirically demonstrated to follow the scaling law of allometric growth. This allometric scaling is based on exponential growth of city size and can be termed “exponential allometry”, which is associated with the concepts of fractals. However, both city population and urban area comply with the course of logistic growth rather than exponential growth. In this paper, I will present a new allometric scaling based on logistic growth to solve the above mentioned problem. The logistic growth is a process of replacement dynamics. Defining a pair of replacement quotients as new measurements, which are functions of urban area and population, we can derive an allometric scaling relation from the logistic processes of urban growth, which can be termed “logistic allometry”. The exponential allometric relation between urban area and population is the approximate expression of the logistic allometric equation when the city size is not large enough. The proper range of the allometric scaling exponent value is reconsidered through the logistic process. Then, a medium-sized city of Henan Province, China, is employed as an example to validate the new allometric relation. The logistic allometry is helpful for further understanding the fractal property and self-organized process of urban evolution in the right perspective

  4. Learning curves in highly skilled chess players: a test of the generality of the power law of practice.

    Science.gov (United States)

    Howard, Robert W

    2014-09-01

    The power law of practice holds that a power function best interrelates skill performance and amount of practice. However, the law's validity and generality are moot. Some researchers argue that it is an artifact of averaging individual exponential curves while others question whether the law generalizes to complex skills and to performance measures other than response time. The present study tested the power law's generality to development over many years of a very complex cognitive skill, chess playing, with 387 skilled participants, most of whom were grandmasters. A power or logarithmic function best fit grouped data but individuals showed much variability. An exponential function usually was the worst fit to individual data. Groups differing in chess talent were compared and a power function best fit the group curve for the more talented players while a quadratic function best fit that for the less talented. After extreme amounts of practice, a logarithmic function best fit grouped data but a quadratic function best fit most individual curves. Individual variability is great and the power law or an exponential law are not the best descriptions of individual chess skill development. Copyright © 2014 Elsevier B.V. All rights reserved.

  5. Escaping the snare of chronological growth and launching a free curve alternative: general deviance as latent growth model.

    Science.gov (United States)

    Wood, Phillip Karl; Jackson, Kristina M

    2013-08-01

    Researchers studying longitudinal relationships among multiple problem behaviors sometimes characterize autoregressive relationships across constructs as indicating "protective" or "launch" factors or as "developmental snares." These terms are used to indicate that initial or intermediary states of one problem behavior subsequently inhibit or promote some other problem behavior. Such models are contrasted with models of "general deviance" over time in which all problem behaviors are viewed as indicators of a common linear trajectory. When fit of the "general deviance" model is poor and fit of one or more autoregressive models is good, this is taken as support for the inhibitory or enhancing effect of one construct on another. In this paper, we argue that researchers consider competing models of growth before comparing deviance and time-bound models. Specifically, we propose use of the free curve slope intercept (FCSI) growth model (Meredith & Tisak, 1990) as a general model to typify change in a construct over time. The FCSI model includes, as nested special cases, several statistical models often used for prospective data, such as linear slope intercept models, repeated measures multivariate analysis of variance, various one-factor models, and hierarchical linear models. When considering models involving multiple constructs, we argue the construct of "general deviance" can be expressed as a single-trait multimethod model, permitting a characterization of the deviance construct over time without requiring restrictive assumptions about the form of growth over time. As an example, prospective assessments of problem behaviors from the Dunedin Multidisciplinary Health and Development Study (Silva & Stanton, 1996) are considered and contrasted with earlier analyses of Hussong, Curran, Moffitt, and Caspi (2008), which supported launch and snare hypotheses. For antisocial behavior, the FCSI model fit better than other models, including the linear chronometric growth curve

  6. An Unusual Exponential Graph

    Science.gov (United States)

    Syed, M. Qasim; Lovatt, Ian

    2014-01-01

    This paper is an addition to the series of papers on the exponential function begun by Albert Bartlett. In particular, we ask how the graph of the exponential function y = e[superscript -t/t] would appear if y were plotted versus ln t rather than the normal practice of plotting ln y versus t. In answering this question, we find a new way to…

  7. A non-iterative method for fitting decay curves with background

    International Nuclear Information System (INIS)

    Mukoyama, T.

    1982-01-01

    A non-iterative method for fitting a decay curve with background is presented. The sum of an exponential function and a constant term is linearized by the use of the difference equation and parameters are determined by the standard linear least-squares fitting. The validity of the present method has been tested against pseudo-experimental data. (orig.)

  8. Economic growth and energy regulation in the environmental Kuznets curve.

    Science.gov (United States)

    Lorente, Daniel Balsalobre; Álvarez-Herranz, Agustín

    2016-08-01

    This study establishes the existence of a pattern of behavior, between economic growth and environmental degradation, consistent with the environmental Kuznets curve (EKC) hypothesis for 17 Organization for Economic Cooperation and Development (OECD) countries between 1990 and 2012. Based on this EKC pattern, it shows that energy regulation measures help reduce per capita greenhouse gas (GHG) emissions. To validate this hypothesis, we also add the explanatory variables: renewable energy promotion, energy innovation processes, and the suppression effect of income level on the contribution of renewable energy sources to total energy consumption. It aims to be a tool for decision-making regarding energy policy. This paper provides a two-stage econometric analysis of instrumental variables with the aim of correcting the existence of endogeneity in the variable GDP per capita, verifying that the instrumental variables used in this research are appropriate for our aim. To this end, it first makes a methodological contribution before incorporating additional variables associated with environmental air pollution into the EKC hypothesis and showing how they positively affect the explanation of the correction in the GHG emission levels. This study concludes that air pollution will not disappear on its own as economic growth increases. Therefore, it is necessary to promote energy regulation measures to reduce environmental pollution.

  9. Fast quantum modular exponentiation

    International Nuclear Information System (INIS)

    Meter, Rodney van; Itoh, Kohei M.

    2005-01-01

    We present a detailed analysis of the impact on quantum modular exponentiation of architectural features and possible concurrent gate execution. Various arithmetic algorithms are evaluated for execution time, potential concurrency, and space trade-offs. We find that to exponentiate an n-bit number, for storage space 100n (20 times the minimum 5n), we can execute modular exponentiation 200-700 times faster than optimized versions of the basic algorithms, depending on architecture, for n=128. Addition on a neighbor-only architecture is limited to O(n) time, whereas non-neighbor architectures can reach O(log n), demonstrating that physical characteristics of a computing device have an important impact on both real-world running time and asymptotic behavior. Our results will help guide experimental implementations of quantum algorithms and devices

  10. Theoretical derivation of anodizing current and comparison between fitted curves and measured curves under different conditions

    Science.gov (United States)

    Chong, Bin; Yu, Dongliang; Jin, Rong; Wang, Yang; Li, Dongdong; Song, Ye; Gao, Mingqi; Zhu, Xufei

    2015-04-01

    Anodic TiO2 nanotubes have been studied extensively for many years. However, the growth kinetics still remains unclear. The systematic study of the current transient under constant anodizing voltage has not been mentioned in the original literature. Here, a derivation and its corresponding theoretical formula are proposed to overcome this challenge. In this paper, the theoretical expressions for the time dependent ionic current and electronic current are derived to explore the anodizing process of Ti. The anodizing current-time curves under different anodizing voltages and different temperatures are experimentally investigated in the anodization of Ti. Furthermore, the quantitative relationship between the thickness of the barrier layer and anodizing time, and the relationships between the ionic/electronic current and temperatures are proposed in this paper. All of the current-transient plots can be fitted consistently by the proposed theoretical expressions. Additionally, it is the first time that the coefficient A of the exponential relationship (ionic current jion = A exp(BE)) has been determined under various temperatures and voltages. And the results indicate that as temperature and voltage increase, ionic current and electronic current both increase. The temperature has a larger effect on electronic current than ionic current. These results can promote the research of kinetics from a qualitative to quantitative level.

  11. Theoretical derivation of anodizing current and comparison between fitted curves and measured curves under different conditions.

    Science.gov (United States)

    Chong, Bin; Yu, Dongliang; Jin, Rong; Wang, Yang; Li, Dongdong; Song, Ye; Gao, Mingqi; Zhu, Xufei

    2015-04-10

    Anodic TiO2 nanotubes have been studied extensively for many years. However, the growth kinetics still remains unclear. The systematic study of the current transient under constant anodizing voltage has not been mentioned in the original literature. Here, a derivation and its corresponding theoretical formula are proposed to overcome this challenge. In this paper, the theoretical expressions for the time dependent ionic current and electronic current are derived to explore the anodizing process of Ti. The anodizing current-time curves under different anodizing voltages and different temperatures are experimentally investigated in the anodization of Ti. Furthermore, the quantitative relationship between the thickness of the barrier layer and anodizing time, and the relationships between the ionic/electronic current and temperatures are proposed in this paper. All of the current-transient plots can be fitted consistently by the proposed theoretical expressions. Additionally, it is the first time that the coefficient A of the exponential relationship (ionic current j(ion) = A exp(BE)) has been determined under various temperatures and voltages. And the results indicate that as temperature and voltage increase, ionic current and electronic current both increase. The temperature has a larger effect on electronic current than ionic current. These results can promote the research of kinetics from a qualitative to quantitative level.

  12. A demographic study of the exponential distribution applied to uneven-aged forests

    Science.gov (United States)

    Jeffrey H. Gove

    2016-01-01

    A demographic approach based on a size-structured version of the McKendrick-Von Foerster equation is used to demonstrate a theoretical link between the population size distribution and the underlying vital rates (recruitment, mortality and diameter growth) for the population of individuals whose diameter distribution is negative exponential. This model supports the...

  13. Fully exponentially correlated wavefunctions for small atoms

    Energy Technology Data Exchange (ETDEWEB)

    Harris, Frank E. [Department of Physics, University of Utah, Salt Lake City, UT 84112 and Quantum Theory Project, University of Florida, P.O. Box 118435, Gainesville, FL 32611 (United States)

    2015-01-22

    Fully exponentially correlated atomic wavefunctions are constructed from exponentials in all the interparticle coordinates, in contrast to correlated wavefunctions of the Hylleraas form, in which only the electron-nuclear distances occur exponentially, with electron-electron distances entering only as integer powers. The full exponential correlation causes many-configuration wavefunctions to converge with expansion length more rapidly than either orbital formulations or correlated wavefunctions of the Hylleraas type. The present contribution surveys the effectiveness of fully exponentially correlated functions for the three-body system (the He isoelectronic series) and reports their application to a four-body system (the Li atom)

  14. Weighted curve-fitting program for the HP 67/97 calculator

    International Nuclear Information System (INIS)

    Stockli, M.P.

    1983-01-01

    The HP 67/97 calculator provides in its standard equipment a curve-fit program for linear, logarithmic, exponential and power functions that is quite useful and popular. However, in more sophisticated applications, proper weights for data are often essential. For this purpose a program package was created which is very similar to the standard curve-fit program but which includes the weights of the data for proper statistical analysis. This allows accurate calculation of the uncertainties of the fitted curve parameters as well as the uncertainties of interpolations or extrapolations, or optionally the uncertainties can be normalized with chi-square. The program is very versatile and allows one to perform quite difficult data analysis in a convenient way with the pocket calculator HP 67/97

  15. Transverse exponential stability and applications

    NARCIS (Netherlands)

    Andrieu, Vincent; Jayawardhana, Bayu; Praly, Laurent

    2016-01-01

    We investigate how the following properties are related to each other: i) A manifold is “transversally” exponentially stable; ii) The “transverse” linearization along any solution in the manifold is exponentially stable; iii) There exists a field of positive definite quadratic forms whose

  16. Evaluation of staphylococcus aureus growth in unirradiated and irradiated cured meats using the Gompertz equation

    International Nuclear Information System (INIS)

    Szczawinski, J.; Szczawinska, M.

    1993-01-01

    1. Sodium nitrite, in concentration of 156 mg/kg, exerted little (from practical point of view) inhibitory effect on S. aureus in cured meat. Its addition caused lag time extension, increase of exponential growth rate, decrease of generation time and maximum population density of staphylococci in samples of cured meat stored at 20 C. 2. Growth curves of Staphylococcus aureus in unirradiated and irradiated (50 kGy) meats cured without sodium nitrite were similar. 3. Irradiation of meat cured with 156 mg/kg sodium nitrite with increasing doses of ionizing radiation (0, 10, 30, 50 kGy) progressively decreased growth rates and lag time and increased generation time and maximum population densities of Staphylococcus aureus in samples inoculated after radiation treatment and incubated at 20 C. (orig.)

  17. Visible bands of ammonia: band strengths, curves of growth, and the spatial distribution of ammonia on Jupiter

    International Nuclear Information System (INIS)

    Lutz, B.L.; Owen, T.

    1980-01-01

    We report room-temperature laboratory studies of the 5520 A (6ν 1 ) and 6475 A (5ν 1 ) bands of self-broadened ammonia at column densities ranging from 1.7--435.7 meter-amagats (m-am). Detailed equivalent-width measurements at 24 different pressure-pathlength combinations corresponding to four pressures between 44 and 689 torr and pathlengths between 32 and 512 m are used to determin curves of growth and integrated band strengths. The band strengths for the 6ν 1 and 5ν 1 overtones are 5520 A: S=0.096 +- 0.005 cm -1 (m-am) -1 and 6475 A: S=0.63 +- 0.03 cm -1 (m-am) -1 , respectively.Using these band strengths and curves of growth, we analyze new spatially resolved spectra of Jupiter showing a nonhomogeneous distribution of ammonia in the Jovian atmosphere. The observed variations in the CH 4 /NH 3 mixing ratio are interpreted as evidence of altitude-dependent depletion of ammonia in the atmosphere

  18. Exponential fed-batch strategy for enhancing biosurfactant production by Bacillus subtilis.

    Science.gov (United States)

    Amin, G A

    2014-01-01

    Surfactin produced by Bacillus subtilis BDCC-TUSA-3 from Maldex-15 was used as a growth-associated product in a conventional batch process. Maldex-15 is a cheap industrial by-product recovered during manufacturing of high fructose syrup from corn starch. Surfactin production was greatly improved in exponential fed-batch fermentation. Maldex-15 and other nutrients were exponentially fed into the culture based on the specific growth rate of the bacterium. In order to maximize surfactin yield and productivity, conversion of different quantities of Maldex-15 into surfactin was investigated in five different fermentation runs. In all runs, most of the Maldex-15 was consumed and converted into surfactin and cell biomass with appreciable efficiencies. The best results were obtained with the fermentation run supplied with 204 g Maldex-15. Up to 36.1 g l(-1) of surfactin and cell biomass of 31.8 g l(-1) were achieved in 12 h. Also, a marked substrate yield of 0.272 g g(-1) and volumetric reactor productivity of 2.58 g 1(-1) h(-1) were obtained, confirming the establishment of a cost-effective commercial surfactin production.

  19. Growth curves in Down syndrome with congenital heart disease

    Directory of Open Access Journals (Sweden)

    Caroline D’Azevedo Sica

    Full Text Available SUMMARY Introduction: To assess dietary habits, nutritional status and food frequency in children and adolescents with Down syndrome (DS and congenital heart disease (CHD. Additionally, we attempted to compare body mass index (BMI classifications according to the World Health Organization (WHO curves and curves developed for individuals with DS. Method: Cross-sectional study including individuals with DS and CHD treated at a referral center for cardiology, aged 2 to 18 years. Weight, height, BMI, total energy and food frequency were measured. Nutritional status was assessed using BMI for age and gender, using curves for evaluation of patients with DS and those set by the WHO. Results: 68 subjects with DS and CHD were evaluated. Atrioventricular septal defect (AVSD was the most common heart disease (52.9%. There were differences in BMI classification between the curves proposed for patients with DS and those proposed by the WHO. There was an association between consumption of vitamin E and polyunsaturated fatty acids. Conclusion: Results showed that individuals with DS are mostly considered normal weight for age, when evaluated using specific curves for DS. Reviews on specific curves for DS would be the recommended practice for health professionals so as to avoid precipitated diagnosis of overweight and/or obesity in this population.

  20. On conjugacy growth of linear groups

    OpenAIRE

    Breuillard, Emmanuel; de Cornulier, Yves; Lubotzky, Alexander; Meiri, Chen

    2011-01-01

    We investigate the conjugacy growth of finitely generated linear groups. We show that finitely generated non-virtually-solvable subgroups of GL_d have uniform exponential conjugacy growth and in fact that the number of distinct polynomials arising as characteristic polynomials of the elements of the ball of radius n for the word metric has exponential growth rate bounded away from 0 in terms of the dimension d only.

  1. Why the Singularity Cannot Happen

    OpenAIRE

    Modis, Theodore

    2012-01-01

    The concept of a Singularity as described in Ray Kurzweil's book cannot happen for a number of reasons. One reason is that all natural growth processes that follow exponential patterns eventually reveal themselves to be following S-curves thus excluding runaway situations. The remaining growth potential from Kurzweil's ''knee'', which could be approximated as the moment when an S-curve pattern begins deviating from the corresponding exponential, is a factor of only one order of magnitude grea...

  2. Growth curve and diet density affect eating motivation, behaviour, and body composition of broiler breeders during rearing

    NARCIS (Netherlands)

    Mozos, de los J.; Garcia Ruiz, A.I.; Hartog, den L.A.; Villamide, M.J.

    2017-01-01

    The aim of this work has been to assess the effect of diet density [control (CON) or 15% diluted (DIL)] and growth curve [recommended by the genetic line (RBW) or 15% heavier (HBW)] and their interaction on BW uniformity, feeding motivation, behavior, and body composition of broiler breeder pullets.

  3. Finite Difference Solution of Elastic-Plastic Thin Rotating Annular Disk with Exponentially Variable Thickness and Exponentially Variable Density

    Directory of Open Access Journals (Sweden)

    Sanjeev Sharma

    2013-01-01

    Full Text Available Elastic-plastic stresses, strains, and displacements have been obtained for a thin rotating annular disk with exponentially variable thickness and exponentially variable density with nonlinear strain hardening material by finite difference method using Von-Mises' yield criterion. Results have been computed numerically and depicted graphically. From the numerical results, it can be concluded that disk whose thickness decreases radially and density increases radially is on the safer side of design as compared to the disk with exponentially varying thickness and exponentially varying density as well as to flat disk.

  4. Economic growth, trade and energy. Implications for the environmental Kuznets curve

    International Nuclear Information System (INIS)

    Suri, Vivek; Chapman, Duane

    1998-01-01

    The environmental Kuznets curve (EKC) hypothesis asserts that pollution follows an inverted-U path with respect to economic growth. The EKC has been explained in terms of structural changes in the composition of economic output and increased environmental regulation at higher income levels. While some authors have incorporated the impact of trade policy orientation on the EKC, the impact of the actual movement between countries of goods that embody pollution has not been considered. This paper attempts to econometrically quantify the effect using pooled cross-country and time-series data. The EKC hypothesis is examined with respect to commercial energy consumption, the source of many serious environmental problems. It was found that while both industrializing and industrialized countries have added to their energy requirements by exporting manufactured goods, the growth has been substantially higher in the former. At the same time, industrialized countries have been able to reduce their energy requirements by importing manufactured goods. Exports of manufactured goods by industrialized countries has thus been an important factor in generating the upward sloping portion of the EKC and imports by industrialized countries have contributed to the downward slope

  5. Simulating Population Growth.

    Science.gov (United States)

    Byington, Scott

    1997-01-01

    Presents a strategy to help students grasp the important implications of population growth. Involves an interactive demonstration that allows students to experience exponential and logistic population growth followed by a discussion of the implications of population-growth principles. (JRH)

  6. Modelling of Creep and Stress Relaxation Test of a Polypropylene Microfibre by Using Fraction-Exponential Kernel

    Directory of Open Access Journals (Sweden)

    Andrea Sorzia

    2016-01-01

    Full Text Available A tensile test until breakage and a creep and relaxation test on a polypropylene fibre are carried out and the resulting creep and stress relaxation curves are fit by a model adopting a fraction-exponential kernel in the viscoelastic operator. The models using fraction-exponential functions are simpler than the complex ones obtained from combination of dashpots and springs and, furthermore, are suitable for fitting experimental data with good approximation allowing, at the same time, obtaining inverse Laplace transform in closed form. Therefore, the viscoelastic response of polypropylene fibres can be modelled straightforwardly through analytical methods. Addition of polypropylene fibres greatly improves the tensile strength of composite materials with concrete matrix. The proposed analytical model can be employed for simulating the mechanical behaviour of composite materials with embedded viscoelastic fibres.

  7. Exponential Hilbert series of equivariant embeddings

    OpenAIRE

    Johnson, Wayne A.

    2018-01-01

    In this article, we study properties of the exponential Hilbert series of a $G$-equivariant projective variety, where $G$ is a semisimple, simply-connected complex linear algebraic group. We prove a relationship between the exponential Hilbert series and the degree and dimension of the variety. We then prove a combinatorial identity for the coefficients of the polynomial representing the exponential Hilbert series. This formula is used in examples to prove further combinatorial identities inv...

  8. Exponential x-ray transform

    International Nuclear Information System (INIS)

    Hazou, I.A.

    1986-01-01

    In emission computed tomography one wants to determine the location and intensity of radiation emitted by sources in the presence of an attenuating medium. If the attenuation is known everywhere and equals a constant α in a convex neighborhood of the support of f, then the problem reduces to that of inverting the exponential x-ray transform P/sub α/. The exponential x-ray transform P/sub μ/ with the attenuation μ variable, is of interest mathematically. For the exponential x-ray transform in two dimensions, it is shown that for a large class of approximate δ functions E, convolution kernels K exist for use in the convolution backprojection algorithm. For the case where the attenuation is constant, exact formulas are derived for calculating the convolution kernels from radial point spread functions. From these an exact inversion formula for the constantly attenuated transform is obtained

  9. Breast lesion characterization using whole-lesion histogram analysis with stretched-exponential diffusion model.

    Science.gov (United States)

    Liu, Chunling; Wang, Kun; Li, Xiaodan; Zhang, Jine; Ding, Jie; Spuhler, Karl; Duong, Timothy; Liang, Changhong; Huang, Chuan

    2018-06-01

    Diffusion-weighted imaging (DWI) has been studied in breast imaging and can provide more information about diffusion, perfusion and other physiological interests than standard pulse sequences. The stretched-exponential model has previously been shown to be more reliable than conventional DWI techniques, but different diagnostic sensitivities were found from study to study. This work investigated the characteristics of whole-lesion histogram parameters derived from the stretched-exponential diffusion model for benign and malignant breast lesions, compared them with conventional apparent diffusion coefficient (ADC), and further determined which histogram metrics can be best used to differentiate malignant from benign lesions. This was a prospective study. Seventy females were included in the study. Multi-b value DWI was performed on a 1.5T scanner. Histogram parameters of whole lesions for distributed diffusion coefficient (DDC), heterogeneity index (α), and ADC were calculated by two radiologists and compared among benign lesions, ductal carcinoma in situ (DCIS), and invasive carcinoma confirmed by pathology. Nonparametric tests were performed for comparisons among invasive carcinoma, DCIS, and benign lesions. Comparisons of receiver operating characteristic (ROC) curves were performed to show the ability to discriminate malignant from benign lesions. The majority of histogram parameters (mean/min/max, skewness/kurtosis, 10-90 th percentile values) from DDC, α, and ADC were significantly different among invasive carcinoma, DCIS, and benign lesions. DDC 10% (area under curve [AUC] = 0.931), ADC 10% (AUC = 0.893), and α mean (AUC = 0.787) were found to be the best metrics in differentiating benign from malignant tumors among all histogram parameters derived from ADC and α, respectively. The combination of DDC 10% and α mean , using logistic regression, yielded the highest sensitivity (90.2%) and specificity (95.5%). DDC 10% and α mean derived from

  10. On the formation of exponential discs

    International Nuclear Information System (INIS)

    Yoshii, Yuzuru; Sommer-Larsen, Jesper

    1989-01-01

    Spiral galaxy discs are characterized by approximately exponential surface luminosity profiles. In this paper the evolutionary equations for a star-forming, viscous disc are solved analytically or semi-analytically. It is shown that approximately exponential stellar surface density profiles result if the viscous time-scale t ν is comparable to the star-formation time scale t * everywhere in the disc. The analytical solutions are used to illuminate further on the issue of why the above mechanism leads to resulting exponential stellar profiles under certain conditions. The sensitivity of the solution to variations of various parameters are investigated and show that the initial gas surface density distribution has to be fairly regular in order that final exponential stellar surface density profiles result. (author)

  11. Atmospheric emissions and economic growth. Environmental Kuznets Curve and Kyoto protocol; Emisiones atmosfericas y crecimiento economico en Espana. La Curve de Kuznets ambiental y el protocolo de Kyoto

    Energy Technology Data Exchange (ETDEWEB)

    Roca Jusmet, J.; Padilla Rosa, E.

    2004-07-01

    From the beginning of the 90s the analysis of the relationships between economic growth and environmental pressures has been influenced by the Environmental Kuznets Curve hypothesis or inverted-U shaped relationship between environmental pressure and per capita income. Following this hypothesis, once achieved certain income level, more economic growth is followed by environmental quality improvement. In this paper, we analyse and discuss the theories that support this hypothesis as well as the empirical evidence on this subject. Further on we analyse the relationship between per capita income and the main environmental pollutants for the case does not support the hypothesis. The empirical evidence shows that economic growth, by itself, does not entail a pollution reduction. (Author) 35 refs.

  12. Metabolic flux analysis during the exponential growth phase of Saccharomyces cerevisiae in wine fermentations.

    Directory of Open Access Journals (Sweden)

    Manuel Quirós

    Full Text Available As a consequence of the increase in global average temperature, grapes with the adequate phenolic and aromatic maturity tend to be overripe by the time of harvest, resulting in increased sugar concentrations and imbalanced C/N ratios in fermenting musts. This fact sets obvious additional hurdles in the challenge of obtaining wines with reduced alcohols levels, a new trend in consumer demands. It would therefore be interesting to understand Saccharomyces cerevisiae physiology during the fermentation of must with these altered characteristics. The present study aims to determine the distribution of metabolic fluxes during the yeast exponential growth phase, when both carbon and nitrogen sources are in excess, using continuous cultures. Two different sugar concentrations were studied under two different winemaking temperature conditions. Although consumption and production rates for key metabolites were severely affected by the different experimental conditions studied, the general distribution of fluxes in central carbon metabolism was basically conserved in all cases. It was also observed that temperature and sugar concentration exerted a higher effect on the pentose phosphate pathway and glycerol formation than on glycolysis and ethanol production. Additionally, nitrogen uptake, both quantitatively and qualitatively, was strongly influenced by environmental conditions. This work provides the most complete stoichiometric model used for Metabolic Flux Analysis of S. cerevisiae in wine fermentations employed so far, including the synthesis and release of relevant aroma compounds and could be used in the design of optimal nitrogen supplementation of wine fermentations.

  13. CURVE LSFIT, Gamma Spectrometer Calibration by Interactive Fitting Method

    International Nuclear Information System (INIS)

    Olson, D.G.

    1992-01-01

    1 - Description of program or function: CURVE and LSFIT are interactive programs designed to obtain the best data fit to an arbitrary curve. CURVE finds the type of fitting routine which produces the best curve. The types of fitting routines available are linear regression, exponential, logarithmic, power, least squares polynomial, and spline. LSFIT produces a reliable calibration curve for gamma ray spectrometry by using the uncertainty value associated with each data point. LSFIT is intended for use where an entire efficiency curve is to be made starting at 30 KeV and continuing to 1836 KeV. It creates calibration curves using up to three least squares polynomial fits to produce the best curve for photon energies above 120 KeV and a spline function to combine these fitted points with a best fit for points below 120 KeV. 2 - Method of solution: The quality of fit is tested by comparing the measured y-value to the y-value calculated from the fitted curve. The fractional difference between these two values is printed for the evaluation of the quality of the fit. 3 - Restrictions on the complexity of the problem - Maxima of: 2000 data points calibration curve output (LSFIT) 30 input data points 3 least squares polynomial fits (LSFIT) The least squares polynomial fit requires that the number of data points used exceed the degree of fit by at least two

  14. Implicit and fully implicit exponential finite difference methods

    Indian Academy of Sciences (India)

    Burgers' equation; exponential finite difference method; implicit exponential finite difference method; ... This paper describes two new techniques which give improved exponential finite difference solutions of Burgers' equation. ... Current Issue

  15. Continuous multivariate exponential extension

    International Nuclear Information System (INIS)

    Block, H.W.

    1975-01-01

    The Freund-Weinman multivariate exponential extension is generalized to the case of nonidentically distributed marginal distributions. A fatal shock model is given for the resulting distribution. Results in the bivariate case and the concept of constant multivariate hazard rate lead to a continuous distribution related to the multivariate exponential distribution (MVE) of Marshall and Olkin. This distribution is shown to be a special case of the extended Freund-Weinman distribution. A generalization of the bivariate model of Proschan and Sullo leads to a distribution which contains both the extended Freund-Weinman distribution and the MVE

  16. Exponential Frequency Spectrum in Magnetized Plasmas

    International Nuclear Information System (INIS)

    Pace, D. C.; Shi, M.; Maggs, J. E.; Morales, G. J.; Carter, T. A.

    2008-01-01

    Measurements of a magnetized plasma with a controlled electron temperature gradient show the development of a broadband spectrum of density and temperature fluctuations having an exponential frequency dependence at frequencies below the ion cyclotron frequency. The origin of the exponential frequency behavior is traced to temporal pulses of Lorentzian shape. Similar exponential frequency spectra are also found in limiter-edge plasma turbulence associated with blob transport. This finding suggests a universal feature of magnetized plasma turbulence leading to nondiffusive, cross-field transport, namely, the presence of Lorentzian shaped pulses

  17. Matrix-exponential description of radiative transfer

    International Nuclear Information System (INIS)

    Waterman, P.C.

    1981-01-01

    By appling the matrix-exponential operator technique to the radiative-transfer equation in discrete form, new analytical solutions are obtained for the transmission and reflection matrices in the limiting cases x >1, where x is the optical depth of the layer. Orthongonality of the eigenvectors of the matrix exponential apparently yields new conditions for determining. Chandrasekhar's characteristic roots. The exact law of reflection for the discrete eigenfunctions is also obtained. Finally, when used in conjuction with the doubling method, the matrix exponential should result in reduction in both computation time and loss of precision

  18. Evaluation of glass leaching as nutrient source for microalgae growth

    International Nuclear Information System (INIS)

    Grabska, N.; Tamayo, A.; Mazo, M. A.; Pascual, L.; Rubio, J.

    2015-01-01

    Three glasses with an elemental composition similar to the nutrient ratio required for Spirulina platensis growth and with different SiO 2 content have been prepared. The glasses were crushed and sieved into 2 different fractions and the effect of the particle size has been studied in terms of the leaching kinetics of each element. The chemical analysis of the leaching water was used for obtaining the dissolution rate curves for each element taking part of the glass composition. From the calculation of the leaching rate constant and the exponential constant of the lixiviation reaction, it has been evaluated the Spirulina platensis growth in ambient normal conditions of light, temperature and pH of the growing media. It has been concluded that, either from the modification of the chemical composition of the glass or its particle size, it is possible to tune the delivery of the nutrients to match the growth rate of Spirulina platensis. (Author)

  19. ERROR VS REJECTION CURVE FOR THE PERCEPTRON

    OpenAIRE

    PARRONDO, JMR; VAN DEN BROECK, Christian

    1993-01-01

    We calculate the generalization error epsilon for a perceptron J, trained by a teacher perceptron T, on input patterns S that form a fixed angle arccos (J.S) with the student. We show that the error is reduced from a power law to an exponentially fast decay by rejecting input patterns that lie within a given neighbourhood of the decision boundary J.S = 0. On the other hand, the error vs. rejection curve epsilon(rho), where rho is the fraction of rejected patterns, is shown to be independent ...

  20. Curvas de crescimento intra-uterino de uma população de alto nível socioeconômico Intrauterine growth curves in a high-income population

    Directory of Open Access Journals (Sweden)

    Conceição A. M. Segre

    2001-06-01

    Full Text Available OBJETIVO: as curvas de percentil constituem uma das formas de avaliação do crescimento intra-uterino e podem predizer doenças do recém-nascido como também caracterizar uma população. Este trabalho teve por objetivo construir as curvas de crescimento intra-uterino dos recém-nascidos da Maternidade do Hospital Albert Einstein (MAE, hospital que atende a uma população de alto nível socioeconômico, e comparar com as curvas de crescimento intra-uterino de uma população norte-americana da Califórnia. MÉTODOS: foram construídas curvas de crescimento intra-uterino a partir do peso do recém-nascido de parto único, tomado logo após o nascimento, e da idade gestacional segundo informações maternas, a partir da 32ª. semana de idade gestacional, abrangendo os nascimentos ocorridos na MAE no período de fevereiro de 1995 a fevereiro de 1999. Foram calculados os percentis 10, 50 e 90 do peso ao nascer para cada idade gestacional e comparados com os das curvas da Califórnia. RESULTADOS: as curvas dos percentis 10 e 50 na população da MAE não diferiram das curvas da Califórnia. Para o percentil 90, a curva da MAE ficou abaixo das curvas da Califórnia. Houve número menor de pequenos e grandes para a idade gestacional (PIG e GIG quando classificados pelas curvas da Califórnia. A classificação em PIG, AIG, GIG mostrou-se relacionada significantemente com o ganho de peso materno nos dois sexos. CONCLUSÕES: as duas populações analisadas segundo as curvas de crescimento intra-uterino são diferentes entre si; deverão ser identificados fatores específicos que atuem na população da MAE.OBJECTIVE: growth curves can be used to assess intrauterine growth, to predict diseases in newborns, and to characterize different populations. The objective of this study was to obtain intrauterine growth curves of newborns from the maternity ward of the Hospital Albert Einstein (MAE and compare them with intrauterine growth curves of a population

  1. Factors determinating the shape of survival curves of Escherichia coli cells irradiated by ionizing radiation with different LET. The dependence of the shape of survival curve on LET

    International Nuclear Information System (INIS)

    Kozubek, S.; Krasavin, E.A.; Fajsi, Ch.

    1984-01-01

    The dependence of the shape of bacterial sUrvival curve in the case of Escherichia coli Wild type, rec - and pol - mutants on linear energy transfer is considered. When increasing LET of the radiation the shouldered survival curves are transformed to exponential ones. In the case of sensitive mutants the transformation is observed for smaller values of LET. The dependence of cell sensitivity on LET calculated on the basis of Landau-Vavilov distribution is compared with earlier calculations. The comparison showed a good agreement between two methods of calculation for ions with 4 MeV per nucleon energy

  2. Can extrauterine growth approximate intrauterine growth? Should it?

    NARCIS (Netherlands)

    Sauer, Pieter J. J.

    Most studies evaluating the growth of preterm infants use the so-called intrauterine growth curve and reference fetus as standards. These curves might not be the optimal standards, however, for several reasons. The curves were constructed from small numbers of infants with uncertainty about

  3. Integrated healthcare networks' performance: a growth curve modeling approach.

    Science.gov (United States)

    Wan, Thomas T H; Wang, Bill B L

    2003-05-01

    This study examines the effects of integration on the performance ratings of the top 100 integrated healthcare networks (IHNs) in the United States. A strategic-contingency theory is used to identify the relationship of IHNs' performance to their structural and operational characteristics and integration strategies. To create a database for the panel study, the top 100 IHNs selected by the SMG Marketing Group in 1998 were followed up in 1999 and 2000. The data were merged with the Dorenfest data on information system integration. A growth curve model was developed and validated by the Mplus statistical program. Factors influencing the top 100 IHNs' performance in 1998 and their subsequent rankings in the consecutive years were analyzed. IHNs' initial performance scores were positively influenced by network size, number of affiliated physicians and profit margin, and were negatively associated with average length of stay and technical efficiency. The continuing high performance, judged by maintaining higher performance scores, tended to be enhanced by the use of more managerial or executive decision-support systems. Future studies should include time-varying operational indicators to serve as predictors of network performance.

  4. Modifying effect of caffeine on cell radiosensitivity in stationary and logarithmic phases of growth

    International Nuclear Information System (INIS)

    Plotnikova, E.D.; Kostenko, G.A.

    1978-01-01

    Studied was reproductive killing of cultivated fibroblasts of a Chinese hamster in stationary and exponential growth phases after gamma irradiation. After cell irradiation in a stationary phase at 1200 rad dose rate and postirradiation incubation in conditioned medium before resowing for 5 hrs the survival rate increased almost 5 times due to the reparation of potential-lethal injuries. Under sodium caffein-benzoate (4 mg/ml) effect on cells in a stationary growth phase for 5 hrs before irradiation the survival rate increased; protection level was almost the same as in case of reduction in a conditioned media. Modification factor of dose curve incline was 1.3. Caffein protective effect may be conjectured to relate to the inhibition of potentially-lethal injury fraction realization

  5. Nonlinear models for fitting growth curves of Nellore cows reared in the Amazon Biome

    Directory of Open Access Journals (Sweden)

    Kedma Nayra da Silva Marinho

    2013-09-01

    Full Text Available Growth curves of Nellore cows were estimated by comparing six nonlinear models: Brody, Logistic, two alternatives by Gompertz, Richards and Von Bertalanffy. The models were fitted to weight-age data, from birth to 750 days of age of 29,221 cows, born between 1976 and 2006 in the Brazilian states of Acre, Amapá, Amazonas, Pará, Rondônia, Roraima and Tocantins. The models were fitted by the Gauss-Newton method. The goodness of fit of the models was evaluated by using mean square error, adjusted coefficient of determination, prediction error and mean absolute error. Biological interpretation of parameters was accomplished by plotting estimated weights versus the observed weight means, instantaneous growth rate, absolute maturity rate, relative instantaneous growth rate, inflection point and magnitude of the parameters A (asymptotic weight and K (maturing rate. The Brody and Von Bertalanffy models fitted the weight-age data but the other models did not. The average weight (A and growth rate (K were: 384.6±1.63 kg and 0.0022±0.00002 (Brody and 313.40±0.70 kg and 0.0045±0.00002 (Von Bertalanffy. The Brody model provides better goodness of fit than the Von Bertalanffy model.

  6. Improvement of mobility edge model by using new density of states with exponential tail for organic diode

    International Nuclear Information System (INIS)

    Muhammad Ammar Khan; Sun Jiu-Xun

    2015-01-01

    The mobility edge (ME) model with single Gaussian density of states (DOS) is simplified based on the recent experimental results about the Einstein relationship. The free holes are treated as being non-degenerate, and the trapped holes are dealt with as being degenerate. This enables the integral for the trapped holes to be easily realized in a program. The J–V curves are obtained through solving drift-diffusion equations. When this model is applied to four organic diodes, an obvious deviation between theoretical curves and experimental data is observed. In order to solve this problem, a new DOS with exponential tail is proposed. The results show that the consistence between J–V curves and experimental data based on a new DOS is far better than that based on the Gaussian DOS. The variation of extracted mobility with temperature can be well described by the Arrhenius relationship. (paper)

  7. A Short-Term Advantage for Syngamy in the Origin of Eukaryotic Sex: Effects of Cell Fusion on Cell Cycle Duration and Other Effects Related to the Duration of the Cell Cycle-Relationship between Cell Growth Curve and the Optimal Size of the Species, and Circadian Cell Cycle in Photosynthetic Unicellular Organisms.

    Science.gov (United States)

    Mancebo Quintana, J M; Mancebo Quintana, S

    2012-01-01

    The origin of sex is becoming a vexatious issue for Evolutionary Biology. Numerous hypotheses have been proposed, based on the genetic effects of sex, on trophic effects or on the formation of cysts and syncytia. Our approach addresses the change in cell cycle duration which would cause cell fusion. Several results are obtained through graphical and mathematical analysis and computer simulations. (1) In poor environments, cell fusion would be an advantageous strategy, as fusion between cells of different size shortens the cycle of the smaller cell (relative to the asexual cycle), and the majority of mergers would occur between cells of different sizes. (2) The easiest-to-evolve regulation of cell proliferation (sexual/asexual) would be by modifying the checkpoints of the cell cycle. (3) A regulation of this kind would have required the existence of the G2 phase, and sex could thus be the cause of the appearance of this phase. Regarding cell cycle, (4) the exponential curve is the only cell growth curve that has no effect on the optimal cell size in unicellular species; (5) the existence of a plateau with no growth at the end of the cell cycle explains the circadian cell cycle observed in unicellular algae.

  8. A Short-Term Advantage for Syngamy in the Origin of Eukaryotic Sex: Effects of Cell Fusion on Cell Cycle Duration and Other Effects Related to the Duration of the Cell Cycle—Relationship between Cell Growth Curve and the Optimal Size of the Species, and Circadian Cell Cycle in Photosynthetic Unicellular Organisms

    Science.gov (United States)

    Mancebo Quintana, J. M.; Mancebo Quintana, S.

    2012-01-01

    The origin of sex is becoming a vexatious issue for Evolutionary Biology. Numerous hypotheses have been proposed, based on the genetic effects of sex, on trophic effects or on the formation of cysts and syncytia. Our approach addresses the change in cell cycle duration which would cause cell fusion. Several results are obtained through graphical and mathematical analysis and computer simulations. (1) In poor environments, cell fusion would be an advantageous strategy, as fusion between cells of different size shortens the cycle of the smaller cell (relative to the asexual cycle), and the majority of mergers would occur between cells of different sizes. (2) The easiest-to-evolve regulation of cell proliferation (sexual/asexual) would be by modifying the checkpoints of the cell cycle. (3) A regulation of this kind would have required the existence of the G2 phase, and sex could thus be the cause of the appearance of this phase. Regarding cell cycle, (4) the exponential curve is the only cell growth curve that has no effect on the optimal cell size in unicellular species; (5) the existence of a plateau with no growth at the end of the cell cycle explains the circadian cell cycle observed in unicellular algae. PMID:22666626

  9. Exponential Expansion in Evolutionary Economics

    DEFF Research Database (Denmark)

    Frederiksen, Peter; Jagtfelt, Tue

    2013-01-01

    This article attempts to solve current problems of conceptual fragmentation within the field of evolutionary economics. One of the problems, as noted by a number of observers, is that the field suffers from an assemblage of fragmented and scattered concepts (Boschma and Martin 2010). A solution...... to this problem is proposed in the form of a model of exponential expansion. The model outlines the overall structure and function of the economy as exponential expansion. The pictographic model describes four axiomatic concepts and their exponential nature. The interactive, directional, emerging and expanding...... concepts are described in detail. Taken together it provides the rudimentary aspects of an economic system within an analytical perspective. It is argued that the main dynamic processes of the evolutionary perspective can be reduced to these four concepts. The model and concepts are evaluated in the light...

  10. Two Aspects of the Simplex Model: Goodness of Fit to Linear Growth Curve Structures and the Analysis of Mean Trends.

    Science.gov (United States)

    Mandys, Frantisek; Dolan, Conor V.; Molenaar, Peter C. M.

    1994-01-01

    Studied the conditions under which the quasi-Markov simplex model fits a linear growth curve covariance structure and determined when the model is rejected. Presents a quasi-Markov simplex model with structured means and gives an example. (SLD)

  11. Method for nonlinear exponential regression analysis

    Science.gov (United States)

    Junkin, B. G.

    1972-01-01

    Two computer programs developed according to two general types of exponential models for conducting nonlinear exponential regression analysis are described. Least squares procedure is used in which the nonlinear problem is linearized by expanding in a Taylor series. Program is written in FORTRAN 5 for the Univac 1108 computer.

  12. Is cancer a pure growth curve or does it follow a kinetics of dynamical structural transformation?

    Science.gov (United States)

    González, Maraelys Morales; Joa, Javier Antonio González; Cabrales, Luis Enrique Bergues; Pupo, Ana Elisa Bergues; Schneider, Baruch; Kondakci, Suleyman; Ciria, Héctor Manuel Camué; Reyes, Juan Bory; Jarque, Manuel Verdecia; Mateus, Miguel Angel O'Farril; González, Tamara Rubio; Brooks, Soraida Candida Acosta; Cáceres, José Luis Hernández; González, Gustavo Victoriano Sierra

    2017-03-07

    Unperturbed tumor growth kinetics is one of the more studied cancer topics; however, it is poorly understood. Mathematical modeling is a useful tool to elucidate new mechanisms involved in tumor growth kinetics, which can be relevant to understand cancer genesis and select the most suitable treatment. The classical Kolmogorov-Johnson-Mehl-Avrami as well as the modified Kolmogorov-Johnson-Mehl-Avrami models to describe unperturbed fibrosarcoma Sa-37 tumor growth are used and compared with the Gompertz modified and Logistic models. Viable tumor cells (1×10 5 ) are inoculated to 28 BALB/c male mice. Modified Gompertz, Logistic, Kolmogorov-Johnson-Mehl-Avrami classical and modified Kolmogorov-Johnson-Mehl-Avrami models fit well to the experimental data and agree with one another. A jump in the time behaviors of the instantaneous slopes of classical and modified Kolmogorov-Johnson-Mehl-Avrami models and high values of these instantaneous slopes at very early stages of tumor growth kinetics are observed. The modified Kolmogorov-Johnson-Mehl-Avrami equation can be used to describe unperturbed fibrosarcoma Sa-37 tumor growth. It reveals that diffusion-controlled nucleation/growth and impingement mechanisms are involved in tumor growth kinetics. On the other hand, tumor development kinetics reveals dynamical structural transformations rather than a pure growth curve. Tumor fractal property prevails during entire TGK.

  13. Bracing can reduce high degree curves and improve aesthetics immediately after the end of growth. Final results of a retrospective case series.

    Science.gov (United States)

    Negrini, Stefano; Donzelli, Sabrina; Lusini, Monia; Zaina, Fabio

    2012-01-01

    Recently it has been shown that idiopathic scoliosis (IS) curves can be reduced with bracing, and it has been proposed that this could be useful in non-surgically treated high degree curves even after Risser 3. Moreover, bracing has been shown to be able to improve aesthetics, and this could be another reason to treat some patients with cosmetic needs. Our aim is to preliminary check if results can be obtained in IS patients after Risser 3. Design. Retrospective uncontrolled cohort study. Inclusion criteria. All IS patients treated on a voluntary basis for aesthetic reasons and/or for curve reduction; Risser 4-5 at start; end of treatment reached. Population. 34 females and 2 males, age 16.2±1.6 years, Cobb angle 27.6°±8.9°. Treatment. Lyon or SPoRT braces 18 to 24 hours/day, specific SEAS exercises, rapid weaning (2-3 hours every 6 months). Outcome criteria: SRS (unchanged; worsened over 6°; over 45° at the end of treatment; surgically treated), radiographic and clinical. Statistics. ANOVA and chi-test. The reported compliance during the 2.8 ± 1.1 treatment years was 95.1%, while residual growth was 0.9 ± 1.1 cm. Improvements were found in 39% of this cohort, (46% in curves over 30°). Only 1 patient progressed 6°. We found highly statistically significant reductions of maximal (-4.4°), thoracic (-6.0°) and thoracolumbar (-6.6°) curves. Statistically significant improvements were found for Aesthetic Index. Before 20 years of age, even in skeletally mature patients, it is possible to reach radiographic and aesthetic improvements, although not as good as during growth. Correction is based on bone growth, but ligaments and neuromuscular control of posture can also be involved.

  14. Balanced growth path solutions of a Boltzmann mean field game model for knowledge growth

    KAUST Repository

    Burger, Martin; Lorz, Alexander; Wolfram, Marie Therese

    2016-01-01

    events or by producing goods with the knowledge they already have. The existence of balanced growth path solutions implies exponential growth of the overall production in time. We prove existence of balanced growth path solutions if the initial

  15. Effect of single-dose x irradiation on the growth curves of a human malignant melanoma transplanted into nude mice

    International Nuclear Information System (INIS)

    Spang-Thomsen, M.; Visfeldt, J.; Nielsen, A.

    1981-01-01

    A human malignant melanoma transplanted into nude mice was exposed to single-dose x irradiation. Experimental growth data described mathematically according to a transformed Gompertz function were used to determine the effect of irradiation on growth delay, growth rate, and tumor shrinkage. The radiation-induced changes in the histology of the tumors were also described. The results showed that irradiation induced a dose-dependent growth delay; this parameter was therefore found suitable for the assessment of relative therapeutic effect. The treatment also induced a dose-dependent reduction in growth rate during regrowth. As a result of this effect on growth rate, extrapolation of tumor shrinkage to the time of treatment became directly misleading as a measure of the effect of the treatment. From this it can be deduced that in therapeutic studies where treatment induces nonparallel posttherapeutic growth curves, growth delay for various tumors and therapies cannot be compared directly. The transformed Gompertz function proved to be extremely well suited for evaluating these conditions

  16. Prediction of fire growth on furniture using CFD

    Science.gov (United States)

    Pehrson, Richard David

    A fire growth calculation method has been developed that couples a computational fluid dynamics (CFD) model with bench scale cone calorimeter test data for predicting the rate of flame spread on compartment contents such as furniture. The commercial CFD code TASCflow has been applied to solve time averaged conservation equations using an algebraic multigrid solver with mass weighted skewed upstream differencing for advection. Closure models include k-e for turbulence, eddy breakup for combustion following a single step irreversible reaction with Arrhenius rate constant, finite difference radiation transfer, and conjugate heat transfer. Radiation properties are determined from concentrations of soot, CO2 and H2O using the narrow band model of Grosshandler and exponential wide band curve fit model of Modak. The growth in pyrolyzing area is predicted by treating flame spread as a series of piloted ignitions based on coupled gas-fluid boundary conditions. The mass loss rate from a given surface element follows the bench scale test data for input to the combustion prediction. The fire growth model has been tested against foam-fabric mattresses and chairs burned in the furniture calorimeter. In general, agreement between model and experiment for peak heat release rate (HRR), time to peak HRR, and total energy lost is within +/-20%. Used as a proxy for the flame spread velocity, the slope of the HRR curve predicted by model agreed with experiment within +/-20% for all but one case.

  17. Impact of Witnessing Violence on Growth Curves for Problem Behaviors among Early Adolescents in Urban and Rural Settings

    Science.gov (United States)

    Farrell, Albert D.; Sullivan, Terri N.

    2004-01-01

    Two studies used latent growth-curve analysis to examine the relation between witnessing violence and changes in problem behaviors (drug use, aggression, and delinquency) and attitudes during early adolescence. In Study 1, six waves of data covering 6th to 8th grades were collected from 731 students in urban schools serving mostly African-American…

  18. Estimating regional centile curves from mixed data sources and countries.

    Science.gov (United States)

    van Buuren, Stef; Hayes, Daniel J; Stasinopoulos, D Mikis; Rigby, Robert A; ter Kuile, Feiko O; Terlouw, Dianne J

    2009-10-15

    Regional or national growth distributions can provide vital information on the health status of populations. In most resource poor countries, however, the required anthropometric data from purpose-designed growth surveys are not readily available. We propose a practical method for estimating regional (multi-country) age-conditional weight distributions based on existing survey data from different countries. We developed a two-step method by which one is able to model data with widely different age ranges and sample sizes. The method produces references both at the country level and at the regional (multi-country) level. The first step models country-specific centile curves by Box-Cox t and Box-Cox power exponential distributions implemented in generalized additive model for location, scale and shape through a common model. Individual countries may vary in location and spread. The second step defines the regional reference from a finite mixture of the country distributions, weighted by population size. To demonstrate the method we fitted the weight-for-age distribution of 12 countries in South East Asia and the Western Pacific, based on 273 270 observations. We modeled both the raw body weight and the corresponding Z score, and obtained a good fit between the final models and the original data for both solutions. We briefly discuss an application of the generated regional references to obtain appropriate, region specific, age-based dosing regimens of drugs used in the tropics. The method is an affordable and efficient strategy to estimate regional growth distributions where the standard costly alternatives are not an option. Copyright (c) 2009 John Wiley & Sons, Ltd.

  19. Height growth and site index curves for western white pine in the Cascade Range of Washington and Oregon.

    Science.gov (United States)

    Robert O. Curtis; Nancy M. Diaz; Gary W. Clendenen

    1990-01-01

    Height growth and site index curves were constructed from stem analyses of mature western white pine (Pinus monticola Dougl. ex D. Don) growing in high-elevation forests of the Cascade Range in the Mount Hood and Gifford Pinchot National Forests of Oregon and Washington, respectively. Alternate systems using reference ages for site index of 50 and...

  20. Comparative research on the transmission-mode GaAs photocathodes of exponential-doping structures

    International Nuclear Information System (INIS)

    Chen Liang; Qian Yun-Sheng; Zhang Yi-Jun; Chang Ben-Kang

    2012-01-01

    Early research has shown that the varied doping structures of the active layer of GaAs photocathodes have been proven to have a higher quantum efficiency than uniform doping structures. On the basis of our early research on the surface photovoltage of GaAs photocathodes, and comparative research before and after activation of reflection-mode GaAs photocathodes, we further the comparative research on transmission-mode GaAs photocathodes. An exponential doping structure is the typical varied doping structure that can form a uniform electric field in the active layer. By solving the one-dimensional diffusion equation for no equilibrium minority carriers of transmission-mode GaAs photocathodes of the exponential doping structure, we can obtain the equations for the surface photovoltage (SPV) curve before activation and the spectral response curve (SRC) after activation. Through experiments and fitting calculations for the designed material, the body-material parameters can be well fitted by the SPV before activation, and proven by the fitting calculation for SRC after activation. Through the comparative research before and after activation, the average surface escape probability (SEP) can also be well fitted. This comparative research method can measure the body parameters and the value of SEP for the transmission-mode GaAs photocathode more exactly than the early method, which only measures the body parameters by SRC after activation. It can also help us to deeply study and exactly measure the parameters of the varied doping structures for transmission-mode GaAs photocathodes, and optimize the Cs-O activation technique in the future. (electromagnetism, optics, acoustics, heat transfer, classical mechanics, and fluid dynamics)

  1. On Exponential Hedging and Related Quadratic Backward Stochastic Differential Equations

    International Nuclear Information System (INIS)

    Sekine, Jun

    2006-01-01

    The dual optimization problem for the exponential hedging problem is addressed with a cone constraint. Without boundedness conditions on the terminal payoff and the drift of the Ito-type controlled process, the backward stochastic differential equation, which has a quadratic growth term in the drift, is derived as a necessary and sufficient condition for optimality via a variational method and dynamic programming. Further, solvable situations are given, in which the value and the optimizer are expressed in closed forms with the help of the Clark-Haussmann-Ocone formula

  2. Environmental quality and economic growth: Searching for environmental Kuznets curves for air and water pollutants in Africa

    International Nuclear Information System (INIS)

    Orubu, Christopher O.; Omotor, Douglason G.

    2011-01-01

    This study investigated the relationship between per capita income and environmental degradation in Africa, using longitudinal data on suspended particulate matter and organic water pollutants. The specific objective was to estimate environmental Kuznets curves for two indicators of environmental quality and to establish whether the estimated relationships conform to the inverted U-shape hypothesis. The results of the empirical investigation generally suggest the existence of an environmental Kuznets curve for suspended particulate matter. In the case of organic water pollutants, the evidence weighs more in favor of rising pollution as per capita income increases. The turning point levels of income established for the two indicators of environmental quality were however generally low, when compared to evidence from existing studies. On the face value, this suggests that African countries may be turning the corner of the environmental Kuznets curve, much faster, and at lower levels of income, much in line with the emerging idea of a 'revised environmental Kuznets curve'. The results also suggest that economic growth and rising incomes may matter in African countries in order to curb pollution from these pollutants, but more stringent policy measures, particularly at the industrial level would be required to curb environmental degradation from organic water pollutants. - Highlights: → The specific objective was to establish whether the relationships conform to the inverted U-shape hypothesis. → Evidence suggests the existence of an environmental Kuznets curve for suspended particulate matter. → The turning point levels of income established for the two indicators were however generally low. → We conclude that African countries may be turning the corner of the environmental Kuznets curve, much faster, and at lower levels of income.

  3. Environmental quality and economic growth: Searching for environmental Kuznets curves for air and water pollutants in Africa

    Energy Technology Data Exchange (ETDEWEB)

    Orubu, Christopher O. [Department of Economics, Delta State University, Abraka (Nigeria); Omotor, Douglason G., E-mail: yomotor@yahoo.com [Department of Economics, Delta State University, Abraka (Nigeria)

    2011-07-15

    This study investigated the relationship between per capita income and environmental degradation in Africa, using longitudinal data on suspended particulate matter and organic water pollutants. The specific objective was to estimate environmental Kuznets curves for two indicators of environmental quality and to establish whether the estimated relationships conform to the inverted U-shape hypothesis. The results of the empirical investigation generally suggest the existence of an environmental Kuznets curve for suspended particulate matter. In the case of organic water pollutants, the evidence weighs more in favor of rising pollution as per capita income increases. The turning point levels of income established for the two indicators of environmental quality were however generally low, when compared to evidence from existing studies. On the face value, this suggests that African countries may be turning the corner of the environmental Kuznets curve, much faster, and at lower levels of income, much in line with the emerging idea of a 'revised environmental Kuznets curve'. The results also suggest that economic growth and rising incomes may matter in African countries in order to curb pollution from these pollutants, but more stringent policy measures, particularly at the industrial level would be required to curb environmental degradation from organic water pollutants. - Highlights: > The specific objective was to establish whether the relationships conform to the inverted U-shape hypothesis. > Evidence suggests the existence of an environmental Kuznets curve for suspended particulate matter. > The turning point levels of income established for the two indicators were however generally low. > We conclude that African countries may be turning the corner of the environmental Kuznets curve, much faster, and at lower levels of income.

  4. DARK MATTER, MAGNETIC FIELDS, AND THE ROTATION CURVE OF THE MILKY WAY

    International Nuclear Information System (INIS)

    Ruiz-Granados, B.; Battaner, E.; Florido, E.; Calvo, J.; Rubiño-Martín, J. A.

    2012-01-01

    The study of the disk rotation curve of our Galaxy at large distances provides an interesting scenario for us to test whether magnetic fields should be considered as a non-negligible dynamical ingredient. By assuming a bulge, an exponential disk for the stellar and gaseous distributions, and a dark halo and disk magnetic fields, we fit the rotation velocity of the Milky Way. In general, when the magnetic contribution is added to the dynamics, a better description of the rotation curve is obtained. Our main conclusion is that magnetic fields should be taken into account for the Milky Way dynamics. Azimuthal magnetic field strengths of B φ ∼ 2 μG at distances of ∼2 R 0 (16 kpc) are able to explain the rise-up for the rotation curve in the outer disk.

  5. The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments.

    Directory of Open Access Journals (Sweden)

    Krzysztof Wrzesinski

    Full Text Available INTRODUCTION: Cellular metabolism can be considered to have two extremes: one is characterized by exponential growth (in 2D cultures and the other by a dynamic equilibrium (in 3D cultures. We have analyzed the proteome and cellular architecture at these two extremes and found that they are dramatically different. RESULTS: Structurally, actin organization is changed, microtubules are increased and keratins 8 and 18 decreased. Metabolically, glycolysis, fatty acid metabolism and the pentose phosphate shunt are increased while TCA cycle and oxidative phosphorylation is unchanged. Enzymes involved in cholesterol and urea synthesis are increased consistent with the attainment of cholesterol and urea production rates seen in vivo. DNA repair enzymes are increased even though cells are predominantly in Go. Transport around the cell--along the microtubules, through the nuclear pore and in various types of vesicles has been prioritized. There are numerous coherent changes in transcription, splicing, translation, protein folding and degradation. The amount of individual proteins within complexes is shown to be highly coordinated. Typically subunits which initiate a particular function are present in increased amounts compared to other subunits of the same complex. SUMMARY: We have previously demonstrated that cells at dynamic equilibrium can match the physiological performance of cells in tissues in vivo. Here we describe the multitude of protein changes necessary to achieve this performance.

  6. The cultural divide: exponential growth in classical 2D and metabolic equilibrium in 3D environments.

    Science.gov (United States)

    Wrzesinski, Krzysztof; Rogowska-Wrzesinska, Adelina; Kanlaya, Rattiyaporn; Borkowski, Kamil; Schwämmle, Veit; Dai, Jie; Joensen, Kira Eyd; Wojdyla, Katarzyna; Carvalho, Vasco Botelho; Fey, Stephen J

    2014-01-01

    Cellular metabolism can be considered to have two extremes: one is characterized by exponential growth (in 2D cultures) and the other by a dynamic equilibrium (in 3D cultures). We have analyzed the proteome and cellular architecture at these two extremes and found that they are dramatically different. Structurally, actin organization is changed, microtubules are increased and keratins 8 and 18 decreased. Metabolically, glycolysis, fatty acid metabolism and the pentose phosphate shunt are increased while TCA cycle and oxidative phosphorylation is unchanged. Enzymes involved in cholesterol and urea synthesis are increased consistent with the attainment of cholesterol and urea production rates seen in vivo. DNA repair enzymes are increased even though cells are predominantly in Go. Transport around the cell--along the microtubules, through the nuclear pore and in various types of vesicles has been prioritized. There are numerous coherent changes in transcription, splicing, translation, protein folding and degradation. The amount of individual proteins within complexes is shown to be highly coordinated. Typically subunits which initiate a particular function are present in increased amounts compared to other subunits of the same complex. We have previously demonstrated that cells at dynamic equilibrium can match the physiological performance of cells in tissues in vivo. Here we describe the multitude of protein changes necessary to achieve this performance.

  7. Practical pulse engineering: Gradient ascent without matrix exponentiation

    Science.gov (United States)

    Bhole, Gaurav; Jones, Jonathan A.

    2018-06-01

    Since 2005, there has been a huge growth in the use of engineered control pulses to perform desired quantum operations in systems such as nuclear magnetic resonance quantum information processors. These approaches, which build on the original gradient ascent pulse engineering algorithm, remain computationally intensive because of the need to calculate matrix exponentials for each time step in the control pulse. In this study, we discuss how the propagators for each time step can be approximated using the Trotter-Suzuki formula, and a further speedup achieved by avoiding unnecessary operations. The resulting procedure can provide substantial speed gain with negligible costs in the propagator error, providing a more practical approach to pulse engineering.

  8. Differences in inhibition by beta-arabinofuranosyladenine (araA) of radiation induced DNA damage repair in exponentially growing and plateau-phase CHO-cells

    International Nuclear Information System (INIS)

    Iliakis, G.; Seaner, R.

    1988-01-01

    The effect of beta-arabinofuranosyladenine (araA) on the repair of radiation induced DNA damage, as measured by the DNA unwinding technique, was studied in exponentially growing and plateau-phase CHO-cells after exposure to X-rays. Induction of DNA damage by radiation was found to be similar in exponentially growing and plateau-phase cells. In the absence of araA, repair of radiation induced DNA damage proceeded with similar kinetics in exponentially growing and plateau-phase cells. AraA at concentrations between 0-1500 μM inhibited DNA repair both in exponentially growing and in plateau-phase cells. However, the degree of inhibition was significantly higher (by a factor of 3) in plateau-phase cells. A similar degree of repair inhibition by araA was observed in plateau-phase cells treated in their conditioned medium, as well as in plateau-phase cells that were transferred in fresh growth medium just before treatment initiation. These results indicate the importance of biochemical parameters associated with alterations in the growth state of the cells for the inhibitory effect of araA and may help in the elucidation of the molecular mechanism(s) underlying repair inhibition by inhibitors of DNA replication. (orig.)

  9. Growth curves and their implications in hand-fed Monk parrots (Myiopsitta monachus

    Directory of Open Access Journals (Sweden)

    Petzinger C

    2015-10-01

    Full Text Available Christina Petzinger,1,2 J Jill Heatley,3 John E Bauer1,2 1Comparative Animal Nutrition Research Laboratory, Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, 2Intercollegiate Faculty of Nutrition, Texas A&M University, 3Zoological Medicine Service, Department of Small Animal Medicine and Surgery, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA Abstract: Monk parrots (Myiopsitta monachus were hand-fed over two chick seasons spanning of 2010 to 2011. Information from the growth curve of chicks hand-fed in 2010 was used to develop a feeding protocol for the 2011 season (Protocol-2011. This protocol addressed the problems of delayed followed by excessive growth experienced by parrots hand fed in 2010. Monk parrots that were hand-fed in 2011 following the new protocol experienced delayed growth after 20 days of age. However, some Monk parrots were fed in excess of Protocol-2011 and did not experience a major delay in growth. The energy requirement equations used to construct Protocol-2011 were low when compared to adult Monk parrot maintenance energy requirements. The data suggest that growing birds do not require approximately twice their adult maintenance energy requirements, as is the case for growing dogs. Additionally, there appear to be fluctuations in energy needs as Monk parrots grow. A major increase in energy needs occurred between days 18 and 23 posthatching, which corresponds to feather development and growth in Monk parrot chicks. Thus, multiple equations estimating energy requirements, rather than just one equation, are likely needed from hatching to fledging in order to ensure adequate energy is provided to chicks. More research on the energy requirements of growing Monk parrots, especially around the time of fledging and weaning, is needed to improve hand-fed methods and potentially the adult health of hand-fed birds. Keywords

  10. Acridine orange as an alternative to optical density to study growth kinetics of Lactobacillus bulgaricus ATCC 7517.

    Science.gov (United States)

    Pak, Dolar; Koo, Ok Kyung; Story, Robert S; O'Bryan, Corliss A; Crandall, Philip G; Lee, Sun-Ok; Ricke, Steven C

    2013-01-01

    In this study we assessed the use of acridine orange as an alternative to optical density to quantify the growth of Lactobacillus bulgaricus ATCC 7517. The growth of bacteria in Lactobacillus de Man Rogosa Sharpe (MRS) medium was measured by both acridine orange (AO) and optical density (OD) measurements for 24 h. The relationship between both methods was compared via correlation analysis. The doubling time of bacteria based on the values of OD600 and AO obtained during 24 h growth were also calculated. The result shows strong correlation of cell growth between OD600 and AO during the first 10 hours of growth, but the correlation was less strong when analyzing the data from 0 to 24 hours. Growth rates, generation time and lag time were also similar. This study indicates that AO could be used in place of OD to prepare growth curves of Lactobacillus bulgaricus during the exponential phase of growth, and to compare growth rates, generation times or lag times.

  11. Implementation of Pollard Rho attack on elliptic curve cryptography over binary fields

    Science.gov (United States)

    Wienardo, Yuliawan, Fajar; Muchtadi-Alamsyah, Intan; Rahardjo, Budi

    2015-09-01

    Elliptic Curve Cryptography (ECC) is a public key cryptosystem with a security level determined by discrete logarithm problem called Elliptic Curve Discrete Logarithm Problem (ECDLP). John M. Pollard proposed an algorithm for discrete logarithm problem based on Monte Carlo method and known as Pollard Rho algorithm. The best current brute-force attack for ECC is Pollard Rho algorithm. In this research we implement modified Pollard Rho algorithm on ECC over GF (241). As the result, the runtime of Pollard Rho algorithm increases exponentially with the increase of the ECC key length. This work also presents the estimated runtime of Pollard Rho attack on ECC over longer bits.

  12. Bubble Collision in Curved Spacetime

    International Nuclear Information System (INIS)

    Hwang, Dong-il; Lee, Bum-Hoon; Lee, Wonwoo; Yeom, Dong-han

    2014-01-01

    We study vacuum bubble collisions in curved spacetime, in which vacuum bubbles were nucleated in the initial metastable vacuum state by quantum tunneling. The bubbles materialize randomly at different times and then start to grow. It is known that the percolation by true vacuum bubbles is not possible due to the exponential expansion of the space among the bubbles. In this paper, we consider two bubbles of the same size with a preferred axis and assume that two bubbles form very near each other to collide. The two bubbles have the same field value. When the bubbles collide, the collided region oscillates back-and-forth and then the collided region eventually decays and disappears. We discuss radiation and gravitational wave resulting from the collision of two bubbles

  13. Growth of Laser Initiated Damage in Fused Silica at 527 nm

    International Nuclear Information System (INIS)

    Norton, M A; Donohue, E E; Hollingsworth, W G; McElroy, J N; Hackel, R P

    2003-01-01

    The effective lifetime of optics is limited by both laser-induced damage and the subsequent growth of laser initiated damage sites. We have measured the growth rate of laser-induced damage in fused silica in both air and vacuum at 527 nm. For damage on the exit surface, the data shows exponential growth in the lateral size of the damage site with shot number. The exponential growth coefficient depends linearly on the laser fluence. The behavior at the fluence threshold for growth is contrasted to that observed at 351 nm. The growth rate was not significantly affected by either the wavelength of the initiating fluence or the presence of 10 torr of air as compared to vacuum. When the damage is located on the input surface, it has both a higher threshold for growth and does not grow exponentially

  14. Numerical study of MHD nanofluid flow and heat transfer past a bidirectional exponentially stretching sheet

    International Nuclear Information System (INIS)

    Ahmad, Rida; Mustafa, M.; Hayat, T.; Alsaedi, A.

    2016-01-01

    Recent advancements in nanotechnology have led to the discovery of new generation coolants known as nanofluids. Nanofluids possess novel and unique characteristics which are fruitful in numerous cooling applications. Current work is undertaken to address the heat transfer in MHD three-dimensional flow of magnetic nanofluid (ferrofluid) over a bidirectional exponentially stretching sheet. The base fluid is considered as water which consists of magnetite–Fe 3 O 4 nanoparticles. Exponentially varying surface temperature distribution is accounted. Problem formulation is presented through the Maxwell models for effective electrical conductivity and effective thermal conductivity of nanofluid. Similarity transformations give rise to a coupled non-linear differential system which is solved numerically. Appreciable growth in the convective heat transfer coefficient is observed when nanoparticle volume fraction is augmented. Temperature exponent parameter serves to enhance the heat transfer from the surface. Moreover the skin friction coefficient is directly proportional to both magnetic field strength and nanoparticle volume fraction. - Highlights: • Nanofluid flow due to exponentially stretching sheet. • Exponentially varying surface temperature distribution is accounted. • Sparrow–Gregg type Hills (SGH) for temperature distribution exist. • Numerical values of local Nusselt number are presented. • Cooling performance of ferrofluid is superior to pure water.

  15. Time indices of multiphasic development in genotypes of sweet cherry are similar from dormancy to cessation of pit growth.

    Science.gov (United States)

    Gibeaut, David M; Whiting, Matthew D; Einhorn, Todd

    2017-02-01

    The archetypical double sigmoid-shaped growth curve of the sweet cherry drupe (Prunus avium) does not address critical development from eco-dormancy to anthesis and has not been correlated to reproductive bud development. Accurate representation of the growth and development of post-anthesis ovaries is confounded by anthesis timing, fruiting-density and the presence of unfertilized and defective ovaries whose growth differs from those that persist to maturation. These factors were addressed to assess pre-anthesis and full-season growth and development of three sweet cherry cultivars, 'Chelan', 'Bing' and 'Sweetheart', differing primarily in seasonal duration and fruit size. Volume was calculated from photographic measurements of reproductive buds, ovaries and pits at all phases of development. A population of unfertilized ovaries was produced using bee-exclusion netting to enable a statistical comparison with an open pollinated population to detect differences in size and shape between successful and failing fruit growth. Anthesis timing and fruiting-density were manipulated by floral extinction at the spur and whole-tree scales. Developmental time indices were analysed using polynomial curve fitting of log-transformed data supported by Richards and logistic functions of asymptotic growth of the pit and maturing fruit, respectively. Pre-anthesis growth began at the completion of eco-dormancy. A slight decline in relative growth rate (RGR) was observed during bud scale separation approx. -16 d from anthesis (DFA) before resumption of exponential growth to a maximum about 14 DFA. After anthesis, reduced growth of unfertilized or defective ovaries was partly discriminated from successful fruit at 5 DFA and completely at 25 DFA. Time indices of RGR inflections were similar among cultivars when adjusted for anthesis date alone, until the end of pit growth. Asymptotic growth of the pit underpinned the declining growth rate of fruit at the end of the first exponential

  16. An allometric scaling relation based on logistic growth of cities

    Science.gov (United States)

    Chen, Yanguang

    2014-08-01

    The relationships between urban area and population size have been empirically demonstrated to follow the scaling law of allometric growth. This allometric scaling is based on exponential growth of city size and can be termed "exponential allometry", which is associated with the concepts of fractals. However, both city population and urban area comply with the course of logistic growth rather than exponential growth. In this paper, I will present a new allometric scaling based on logistic growth to solve the abovementioned problem. The logistic growth is a process of replacement dynamics. Defining a pair of replacement quotients as new measurements, which are functions of urban area and population, we can derive an allometric scaling relation from the logistic processes of urban growth, which can be termed "logistic allometry". The exponential allometric relation between urban area and population is the approximate expression of the logistic allometric equation when the city size is not large enough. The proper range of the allometric scaling exponent value is reconsidered through the logistic process. Then, a medium-sized city of Henan Province, China, is employed as an example to validate the new allometric relation. The logistic allometry is helpful for further understanding the fractal property and self-organized process of urban evolution in the right perspective.

  17. ESTIMATION OF PARAMETERS AND RELIABILITY FUNCTION OF EXPONENTIATED EXPONENTIAL DISTRIBUTION: BAYESIAN APPROACH UNDER GENERAL ENTROPY LOSS FUNCTION

    Directory of Open Access Journals (Sweden)

    Sanjay Kumar Singh

    2011-06-01

    Full Text Available In this Paper we propose Bayes estimators of the parameters of Exponentiated Exponential distribution and Reliability functions under General Entropy loss function for Type II censored sample. The proposed estimators have been compared with the corresponding Bayes estimators obtained under Squared Error loss function and maximum likelihood estimators for their simulated risks (average loss over sample space.

  18. Using bivariate latent basis growth curve analysis to better understand treatment outcome in youth with anorexia nervosa.

    Science.gov (United States)

    Byrne, Catherine E; Wonderlich, Joseph A; Curby, Timothy; Fischer, Sarah; Lock, James; Le Grange, Daniel

    2018-04-25

    This study explored the relation between eating-related obsessionality and weight restoration utilizing bivariate latent basis growth curve modelling. Eating-related obsessionality is a moderator of treatment outcome for adolescents with anorexia nervosa (AN). This study examined the degree to which the rate of change in eating-related obsessionality was associated with the rate of change in weight over time in family-based treatment (FBT) and individual therapy for AN. Data were drawn from a 2-site randomized controlled trial that compared FBT and adolescent focused therapy for AN. Bivariate latent basis growth curves were used to examine the differences of the relations between trajectories of body weight and symptoms associated with eating and weight obsessionality. In the FBT group, the slope of eating-related obsessionality scores and the slope of weight were significantly (negatively) correlated. This finding indicates that a decrease in overall eating-relating obsessionality is significantly associated with an increase in weight for individuals who received FBT. However, there was no relation between change in obsessionality scores and change in weight in the adolescent focused therapy group. Results suggest that FBT has a specific impact on both weight gain and obsessive compulsive behaviour that is distinct from individual therapy. Copyright © 2018 John Wiley & Sons, Ltd and Eating Disorders Association.

  19. Human population and atmospheric carbon dioxide growth dynamics: Diagnostics for the future

    Science.gov (United States)

    Hüsler, A. D.; Sornette, D.

    2014-10-01

    We analyze the growth rates of human population and of atmospheric carbon dioxide by comparing the relative merits of two benchmark models, the exponential law and the finite-time-singular (FTS) power law. The later results from positive feedbacks, either direct or mediated by other dynamical variables, as shown in our presentation of a simple endogenous macroeconomic dynamical growth model describing the growth dynamics of coupled processes involving human population (labor in economic terms), capital and technology (proxies by CO2 emissions). Human population in the context of our energy intensive economies constitutes arguably the most important underlying driving variable of the content of carbon dioxide in the atmosphere. Using some of the best databases available, we perform empirical analyses confirming that the human population on Earth has been growing super-exponentially until the mid-1960s, followed by a decelerated sub-exponential growth, with a tendency to plateau at just an exponential growth in the last decade with an average growth rate of 1.0% per year. In contrast, we find that the content of carbon dioxide in the atmosphere has continued to accelerate super-exponentially until 1990, with a transition to a progressive deceleration since then, with an average growth rate of approximately 2% per year in the last decade. To go back to CO2 atmosphere contents equal to or smaller than the level of 1990 as has been the broadly advertised goals of international treaties since 1990 requires herculean changes: from a dynamical point of view, the approximately exponential growth must not only turn to negative acceleration but also negative velocity to reverse the trend.

  20. On Uniform Exponential Trichotomy in Banach Spaces

    Directory of Open Access Journals (Sweden)

    Kovacs Monteola Ilona

    2014-06-01

    Full Text Available In this paper we consider three concepts of uniform exponential trichotomy on the half-line in the general framework of evolution operators in Banach spaces. We obtain a systematic classification of uniform exponential trichotomy concepts and the connections between them.

  1. Anterior Overgrowth in Primary Curves, Compensatory Curves and Junctional Segments in Adolescent Idiopathic Scoliosis.

    Science.gov (United States)

    Schlösser, Tom P C; van Stralen, Marijn; Chu, Winnie C W; Lam, Tsz-Ping; Ng, Bobby K W; Vincken, Koen L; Cheng, Jack C Y; Castelein, René M

    2016-01-01

    Although much attention has been given to the global three-dimensional aspect of adolescent idiopathic scoliosis (AIS), the accurate three-dimensional morphology of the primary and compensatory curves, as well as the intervening junctional segments, in the scoliotic spine has not been described before. A unique series of 77 AIS patients with high-resolution CT scans of the spine, acquired for surgical planning purposes, were included and compared to 22 healthy controls. Non-idiopathic curves were excluded. Endplate segmentation and local longitudinal axis in endplate plane enabled semi-automatic geometric analysis of the complete three-dimensional morphology of the spine, taking inter-vertebral rotation, intra-vertebral torsion and coronal and sagittal tilt into account. Intraclass correlation coefficients for interobserver reliability were 0.98-1.00. Coronal deviation, axial rotation and the exact length discrepancies in the reconstructed sagittal plane, as defined per vertebra and disc, were analyzed for each primary and compensatory curve as well as for the junctional segments in-between. The anterior-posterior difference of spinal length, based on "true" anterior and posterior points on endplates, was +3.8% for thoracic and +9.4% for (thoraco)lumbar curves, while the junctional segments were almost straight. This differed significantly from control group thoracic kyphosis (-4.1%; P<0.001) and lumbar lordosis (+7.8%; P<0.001). For all primary as well as compensatory curves, we observed linear correlations between the coronal Cobb angle, axial rotation and the anterior-posterior length difference (r≥0.729 for thoracic curves; r≥0.485 for (thoraco)lumbar curves). Excess anterior length of the spine in AIS has been described as a generalized growth disturbance, causing relative anterior spinal overgrowth. This study is the first to demonstrate that this anterior overgrowth is not a generalized phenomenon. It is confined to the primary as well as the

  2. Exponential mean-square stability of two classes of theta Milstein methods for stochastic delay differential equations

    Science.gov (United States)

    Rouz, Omid Farkhondeh; Ahmadian, Davood; Milev, Mariyan

    2017-12-01

    This paper establishes exponential mean square stability of two classes of theta Milstein methods, namely split-step theta Milstein (SSTM) method and stochastic theta Milstein (STM) method, for stochastic differential delay equations (SDDEs). We consider the SDDEs problem under a coupled monotone condition on drift and diffusion coefficients, as well as a necessary linear growth condition on the last term of theta Milstein method. It is proved that the SSTM method with θ ∈ [0, ½] can recover the exponential mean square stability of the exact solution with some restrictive conditions on stepsize, but for θ ∈ (½, 1], we proved that the stability results hold for any stepsize. Then, based on the stability results of SSTM method, we examine the exponential mean square stability of the STM method and obtain the similar stability results to that of the SSTM method. In the numerical section the figures show thevalidity of our claims.

  3. Relations between the development of school investment, self-confidence, and language achievement in elementary education: A multivariate latent growth curve approach

    NARCIS (Netherlands)

    Stoel, R.D.; Peetsma, T.T.D.; Roeleveld, J.

    2001-01-01

    Latent growth curve (LGC) analysis of longitudinal data for pupils' school investment, self confidence and language ability is presented. A multivariate model is tested that relates the three developmental processes to each other and to intelligence. All processes show significant differences

  4. PENILAIAN PROGRAM PRAKTIKUM TERHADAP PENINGKATAN KUALITI GURU PRA PERKHIDMATAN: ANALISIS BERDASARKAN LATENT GROWTH CURVE MODELLING

    Directory of Open Access Journals (Sweden)

    Azizah Sarkowi

    2015-12-01

    Full Text Available Practicum is an important component in teacher education programs. This study identify the improvement in the quality of pre-service teachers for three phases practicum. Multi-point prospective panel study has been conducted on a 541 pre-service teachers at the Institute of Teacher Education. Teacher’s quality is measured based on the achievement of program learning outcomes. Based on matching last six digit identification card number for three studies series, 337 questionnaires were analyzed using a latent growth curve model using AMOS 18.0. Latent Analysis shows that the model achieve goodness of fit. There is a linear trend of improvement in the performance of the three phases of the practicum. This increase varies between individuals and the rate of growth depends on the level of achievement at practicum phase I. Studies indicate that the increase in the practicum period of teacher education policy should be continued.

  5. ESTIMATION ACCURACY OF EXPONENTIAL DISTRIBUTION PARAMETERS

    Directory of Open Access Journals (Sweden)

    muhammad zahid rashid

    2011-04-01

    Full Text Available The exponential distribution is commonly used to model the behavior of units that have a constant failure rate. The two-parameter exponential distribution provides a simple but nevertheless useful model for the analysis of lifetimes, especially when investigating reliability of technical equipment.This paper is concerned with estimation of parameters of the two parameter (location and scale exponential distribution. We used the least squares method (LSM, relative least squares method (RELS, ridge regression method (RR,  moment estimators (ME, modified moment estimators (MME, maximum likelihood estimators (MLE and modified maximum likelihood estimators (MMLE. We used the mean square error MSE, and total deviation TD, as measurement for the comparison between these methods. We determined the best method for estimation using different values for the parameters and different sample sizes

  6. Time-resolved infrared stimulated luminescence signals in feldspars: Analysis based on exponential and stretched exponential functions

    International Nuclear Information System (INIS)

    Pagonis, V.; Morthekai, P.; Singhvi, A.K.; Thomas, J.; Balaram, V.; Kitis, G.; Chen, R.

    2012-01-01

    Time-resolved infrared-stimulated luminescence (TR-IRSL) signals from feldspar samples have been the subject of several recent experimental studies. These signals are of importance in the field of luminescence dating, since they exhibit smaller fading effects than the commonly employed continuous-wave infrared signals (CW-IRSL). This paper presents a semi-empirical analysis of TR-IRSL data from feldspar samples, by using a linear combination of exponential and stretched exponential (SE) functions. The best possible estimates of the five parameters in this semi-empirical approach are obtained using five popular commercially available software packages, and by employing a variety of global optimization techniques. The results from all types of software and from the different fitting algorithms were found to be in close agreement with each other, indicating that a global optimum solution has likely been reached during the fitting process. Four complete sets of TR-IRSL data on well-characterized natural feldspars were fitted by using such a linear combination of exponential and SE functions. The dependence of the extracted fitting parameters on the stimulation temperature is discussed within the context of a recently proposed model of luminescence processes in feldspar. Three of the four feldspar samples studied in this paper are K-rich, and these exhibited different behavior at higher stimulation temperatures, than the fourth sample which was a Na-rich feldspar. The new method of analysis proposed in this paper can help isolate mathematically the more thermally stable components, and hence could lead to better dating applications in these materials. - Highlights: ► TR-IRSL from four feldspars were analyzed using exponential and stretched exponential functions. ► A variety of global optimization techniques give good agreement. ► Na-rich sample behavior is different from the three K-rich samples. ► Experimental data are fitted for stimulation temperatures

  7. Multivariate Marshall and Olkin Exponential Minification Process ...

    African Journals Online (AJOL)

    A stationary bivariate minification process with bivariate Marshall-Olkin exponential distribution that was earlier studied by Miroslav et al [15]is in this paper extended to multivariate minification process with multivariate Marshall and Olkin exponential distribution as its stationary marginal distribution. The innovation and the ...

  8. Transcriptome Analysis of Liangshan Pig Muscle Development at the Growth Curve Inflection Point and Asymptotic Stages Using Digital Gene Expression Profiling

    Science.gov (United States)

    Du, Jingjing; Liu, Chendong; Wu, Xiaoqian; Pu, Qiang; Fu, Yuhua; Tang, Qianzi; Liu, Yuanrui; Li, Qiang; Yang, Runlin; Li, Xuewei; Tang, Guoqing; Jiang, Yanzhi; Li, Mingzhou; Zhang, Shunhua; Zhu, Li

    2015-01-01

    Animal growth curves can provide essential information for animal breeders to optimize feeding and management strategies. However, the genetic mechanism underlying the phenotypic differentiation between the inflection point and asymptotic stages of the growth curve is not well characterized. Here, we employed Liangshan pigs in stages of growth at the inflection point (under inflection point: UIP) and the two asymptotic stages (before the inflection point: BIP, after the inflection point: AIP) as models to survey global gene expression in the longissimus dorsi muscle using digital gene expression (DGE) tag profiling. We found Liangshan pigs reached maximum growth rate (UIP) at 163.6 days of age and a weight of 134.6 kg. The DGE libraries generated 117 million reads of 5.89 gigabases in length. 21,331, 20,996 and 20,139 expressed transcripts were identified BIP, UIP and AIP, respectively. Among them, we identified 757 differentially expressed genes (DEGs) between BIP and UIP, and 271 DEGs between AIP and UIP. An enrichment analysis of DEGs proved the immune system was strengthened in the AIP stage. Energy metabolism rate, global transcriptional activity and bone development intensity were highest UIP. Meat from Liangshan pigs had the highest intramuscular fat content and most favorable fatty acid composition in the AIP. Three hundred eighty (27.70%) specific expression genes were highly enriched in QTL regions for growth and meat quality traits. This study completed a comprehensive analysis of diverse genetic mechanisms underlying the inflection point and asymptotic stages of growth. Our findings will serve as an important resource in the understanding of animal growth and development in indigenous pig breeds. PMID:26292092

  9. Improvement of the exponential experiment system for the automatical and accurate measurement of the exponential decay constant

    International Nuclear Information System (INIS)

    Shin, Hee Sung; Jang, Ji Woon; Lee, Yoon Hee; Hwang, Yong Hwa; Kim, Ho Dong

    2004-01-01

    The previous exponential experiment system has been improved for the automatical and accurate axial movement of the neutron source and detector with attaching the automatical control system which consists of a Programmable Logical Controller(PLC) and a stepping motor set. The automatic control program which controls MCA and PLC consistently has been also developed on the basis of GENIE 2000 library. The exponential experiments have been carried out for Kori 1 unit spent fuel assemblies, C14, J14 and G23, and Kori 2 unit spent fuel assembly, J44, using the improved systematical measurement system. As the results, the average exponential decay constants for 4 assemblies are determined to be 0.1302, 0.1267, 0.1247, and 0.1210, respectively, with the application of poisson regression

  10. R-curve behaviour of ferroelectric ceramics

    International Nuclear Information System (INIS)

    Egorov, N.Ya.; Kramarov, S.O.

    2004-01-01

    The attempt's made to identify and evaluate the regularities of developing the fractures in the ferroelectric ceramics and also-study the effect of the polishing operation on the strength characteristics of the piezoceramics. The R-curve behaviour in the ferroelectric ceramics is studied on the samples of the barium titanate and lead zirconate-titanate by the four-point bending with controlled surface fractures. It is established that increasing curve of resistance to the fracture growth is observed in the piezoceramics under the conditions of the fracture stable growth. The results obtained on the polished samples prove that the mechanical processing introduces the compression surface stresses into the piezoceramic materials [ru

  11. Fluid particles only separate exponentially in the dissipation range of turbulence after extremely long times

    Science.gov (United States)

    Dhariwal, Rohit; Bragg, Andrew D.

    2018-03-01

    In this paper, we consider how the statistical moments of the separation between two fluid particles grow with time when their separation lies in the dissipation range of turbulence. In this range, the fluid velocity field varies smoothly and the relative velocity of two fluid particles depends linearly upon their separation. While this may suggest that the rate at which fluid particles separate is exponential in time, this is not guaranteed because the strain rate governing their separation is a strongly fluctuating quantity in turbulence. Indeed, Afik and Steinberg [Nat. Commun. 8, 468 (2017), 10.1038/s41467-017-00389-8] argue that there is no convincing evidence that the moments of the separation between fluid particles grow exponentially with time in the dissipation range of turbulence. Motivated by this, we use direct numerical simulations (DNS) to compute the moments of particle separation over very long periods of time in a statistically stationary, isotropic turbulent flow to see if we ever observe evidence for exponential separation. Our results show that if the initial separation between the particles is infinitesimal, the moments of the particle separation first grow as power laws in time, but we then observe convincing evidence that at sufficiently long times the moments do grow exponentially. However, this exponential growth is only observed after extremely long times ≳200 τη , where τη is the Kolmogorov time scale. This is due to fluctuations in the strain rate about its mean value measured along the particle trajectories, the effect of which on the moments of the particle separation persists for very long times. We also consider the backward-in-time (BIT) moments of the article separation, and observe that they too grow exponentially in the long-time regime. However, a dramatic consequence of the exponential separation is that at long times the difference between the rate of the particle separation forward in time (FIT) and BIT grows

  12. MICA: Multiple interval-based curve alignment

    Science.gov (United States)

    Mann, Martin; Kahle, Hans-Peter; Beck, Matthias; Bender, Bela Johannes; Spiecker, Heinrich; Backofen, Rolf

    2018-01-01

    MICA enables the automatic synchronization of discrete data curves. To this end, characteristic points of the curves' shapes are identified. These landmarks are used within a heuristic curve registration approach to align profile pairs by mapping similar characteristics onto each other. In combination with a progressive alignment scheme, this enables the computation of multiple curve alignments. Multiple curve alignments are needed to derive meaningful representative consensus data of measured time or data series. MICA was already successfully applied to generate representative profiles of tree growth data based on intra-annual wood density profiles or cell formation data. The MICA package provides a command-line and graphical user interface. The R interface enables the direct embedding of multiple curve alignment computation into larger analyses pipelines. Source code, binaries and documentation are freely available at https://github.com/BackofenLab/MICA

  13. Both nursery and field performance determine suitable nitrogen supply of nursery-grown, exponentially fertilized Chinese pine

    Science.gov (United States)

    Jiaxi Wang; Guolei Li; Jeremiah R. Pinto; Jiajia Liu; Wenhui Shi; Yong Liu

    2015-01-01

    Optimum fertilization levels are often determined solely from nursery growth responses. However, it is the performance of the seedling on the outplanting site that is the most important. For Pinus species seedlings, little information is known about the field performance of plants cultured with different nutrient rates, especially with exponential fertilization. In...

  14. Longitudinal Examination of Procrastination and Anxiety, and Their Relation to Self-Efficacy for Self- Regulated Learning: Latent Growth Curve Modeling

    Science.gov (United States)

    Yerdelen, Sündüs; McCaffrey, Adam; Klassen, Robert M.

    2016-01-01

    This study investigated the longitudinal association between students' anxiety and procrastination and the relation of self-efficacy for self-regulation to these constructs. Latent Growth Curve Modeling was used to analyze data gathered from 182 undergraduate students (134 female, 48 male) at 4 times during a semester. Our results showed that…

  15. Exponential Stability of Switched Positive Homogeneous Systems

    Directory of Open Access Journals (Sweden)

    Dadong Tian

    2017-01-01

    Full Text Available This paper studies the exponential stability of switched positive nonlinear systems defined by cooperative and homogeneous vector fields. In order to capture the decay rate of such systems, we first consider the subsystems. A sufficient condition for exponential stability of subsystems with time-varying delays is derived. In particular, for the corresponding delay-free systems, we prove that this sufficient condition is also necessary. Then, we present a sufficient condition of exponential stability under minimum dwell time switching for the switched positive nonlinear systems. Some results in the previous literature are extended. Finally, a numerical example is given to demonstrate the effectiveness of the obtained results.

  16. Pre- and postnatal growth phenomena of Burchell's Zebra Equus Burchelli Antiquorum

    Directory of Open Access Journals (Sweden)

    G.L. Smuts

    1975-07-01

    Full Text Available Between 1969 and 1972 growth data were collected from 175 zebra Equus burchelli antiquorum and 138 zebra embryos and foetuses from the Central District of the Kruger National Park, Republic of South Africa. Statistical analysis of data indicated no significant difference between body mass of adult stallions (range == 267,3 to 373,3 kg; mean = 318,5 kg; n = 57 and adult non-pregnant mares (range = 272,6 to 386,9 kg; mean = 321,6 kg; n = 51 (t = 0,587. The heaviest zebra had a body mass of 429,4 kilogram. This was a pregnant mare carrying a 35,2 kg foetus. Von Bertalanffy growth curves indicated that shoulder heights in young zebra may reach the adult range by one year of age, the adult body mass range is, however, only attained after three years of age. These curves also showed that age classification of free roaming zebra is only reliable up to the age of about two years, after which individual variation is too great. Stallions were significantly taller at the shoulder than mares (mean = 1,8 cm (t = 2,032 and neck thickness was the only body dimension showing visible sexual dimorphism in adults. Here the stallion had a neck girth on average 8,1 cm greater than the mare. Regression equations for estimating body mass from body dimensions were calculated by using a standard logarithmic transformation and fitting a linear regression by the method of least squares and also by undertaking standard straight line linear regression analyses. Exponential curves obtained by the first method indicated that growth was not isometric (not linear and that the ratios of any of the dimensions of length to body mass were con- stantly changing, i.e. growth is allometric. Marked allometric growth differences existed between the two sexes except in the case of the heart girth-body mass relationship. Comparison of growth data from E. b. antiquorum with that of E. b. boehmi from Tanzania (Sachs 1967, indicates that E. b. antiquorum is considerably larger. Body masses

  17. Intraoperative length and tension curves of human eye muscles. Including stiffness in passive horizontal eye movement in awake volunteers

    NARCIS (Netherlands)

    H.J. Simonsz (Huib); G.H. Kolling (Gerold); H. Kaufmann (Herbert); B. van Dijk (Bob)

    1986-01-01

    textabstractIntraoperative continuous-registration length and tension curves of attached and detached eye muscles were made in 18 strabismic patients under general anesthesia. For relaxed eye muscles, we found an exponential relation between length and tension. An increased stiffness was quantified

  18. Central limit theorem and deformed exponentials

    International Nuclear Information System (INIS)

    Vignat, C; Plastino, A

    2007-01-01

    The central limit theorem (CLT) can be ranked among the most important ones in probability theory and statistics and plays an essential role in several basic and applied disciplines, notably in statistical thermodynamics. We show that there exists a natural extension of the CLT from exponentials to so-called deformed exponentials (also denoted as q-Gaussians). Our proposal applies exactly in the usual conditions in which the classical CLT is used. (fast track communication)

  19. Exponential growth of new chemicals and evolution of information relevant to risk control.

    Science.gov (United States)

    Binetti, Roberto; Costamagna, Francesca Marina; Marcello, Ida

    2008-01-01

    The number of new chemicals synthesized and marketed increases exponentially. The database CAS REGISTRY at present contains more than 33 million organic and inorganic substances. However, the little information regarding the potential hazard associated with a large amount of chemicals is an old known problem in the European Union and also in the United States. This critical problem may find a solution in the collaboration of the different involved countries and in a planned task setting at international level. Both in the United States (e.g., the "Gore Initiative") and in European Union (the REACH policy) a big effort has been dedicated to this solution, within standardized procedures and an appropriate collaboration.

  20. Investigation of various growth mechanisms of solid tumour growth within the linear-quadratic model for radiotherapy

    International Nuclear Information System (INIS)

    McAneney, H; O'Rourke, S F C

    2007-01-01

    The standard linear-quadratic survival model for radiotherapy is used to investigate different schedules of radiation treatment planning to study how these may be affected by different tumour repopulation kinetics between treatments. The laws for tumour cell repopulation include the logistic and Gompertz models and this extends the work of Wheldon et al (1977 Br. J. Radiol. 50 681), which was concerned with the case of exponential re-growth between treatments. Here we also consider the restricted exponential model. This has been successfully used by Panetta and Adam (1995 Math. Comput. Modelling 22 67) in the case of chemotherapy treatment planning.Treatment schedules investigated include standard fractionation of daily treatments, weekday treatments, accelerated fractionation, optimized uniform schedules and variation of the dosage and α/β ratio, where α and β are radiobiological parameters for the tumour tissue concerned. Parameters for these treatment strategies are extracted from the literature on advanced head and neck cancer, prostate cancer, as well as radiosensitive parameters. Standardized treatment protocols are also considered. Calculations based on the present analysis indicate that even with growth laws scaled to mimic initial growth, such that growth mechanisms are comparable, variation in survival fraction to orders of magnitude emerged. Calculations show that the logistic and exponential models yield similar results in tumour eradication. By comparison the Gompertz model calculations indicate that tumours described by this law result in a significantly poorer prognosis for tumour eradication than either the exponential or logistic models. The present study also shows that the faster the tumour growth rate and the higher the repair capacity of the cell line, the greater the variation in outcome of the survival fraction. Gaps in treatment, planned or unplanned, also accentuate the differences of the survival fraction given alternative growth

  1. Planktonic growth and biofilm formation profiles in Candida haemulonii species complex.

    Science.gov (United States)

    Ramos, Lívia S; Oliveira, Simone S C; Souto, Xênia M; Branquinha, Marta H; Santos, André L S

    2017-10-01

    Candida haemulonii species complex have emerged as multidrug-resistant yeasts able to cause fungemia worldwide. However, very little is known regarding their physiology and virulence factors. In this context, planktonic growth and biofilm formation of Brazilian clinical isolates of Candida haemulonii (n = 5), Candida duobushaemulonii (n = 4), and Candida haemulonii var. vulnera (n = 3) were reported. Overall, the fungal planktonic growth curves in Sabouraud dextrose broth reached the exponential phase in 48 h at 37°C. All the clinical isolates formed biofilm on polystyrene in a time-dependent event, as judged by the parameters evaluated: biomass (crystal violet staining), metabolic activity (XTT reduction), and extracellular matrix (safranin incorporation). No statistically significant differences were observed when the average measurements among the three Candida species were compared regarding both planktonic and biofilm lifestyles; however, typical isolate-specific differences were clearly noticed in fungal growth kinetics. © The Author 2017. Published by Oxford University Press on behalf of The International Society for Human and Animal Mycology. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  2. Firm Growth Function and Extended-Gibrat’s Property

    Directory of Open Access Journals (Sweden)

    Atushi Ishikawa

    2016-01-01

    Full Text Available We analytically show that the logarithmic average sales of firms first follow power-law growth and subsequently follow exponential growth, if the growth-rate distributions of the sales obey the extended-Gibrat’s property and Gibrat’s law. Here, the extended-Gibrat’s property and Gibrat’s law are statistically observed in short-term data, which denote the dependence of the growth-rate distributions on the initial values. In the derivation, we analytically show that the parameter of the extended-Gibrat’s property is identical to the power-law growth exponent and that it also decides the parameter of the exponential growth. By employing around one million bits of exhaustive sales data of Japanese firms in the ORBIS database, we confirmed our analytic results.

  3. Nonparametric estimation of age-specific reference percentile curves with radial smoothing.

    Science.gov (United States)

    Wan, Xiaohai; Qu, Yongming; Huang, Yao; Zhang, Xiao; Song, Hanping; Jiang, Honghua

    2012-01-01

    Reference percentile curves represent the covariate-dependent distribution of a quantitative measurement and are often used to summarize and monitor dynamic processes such as human growth. We propose a new nonparametric method based on a radial smoothing (RS) technique to estimate age-specific reference percentile curves assuming the underlying distribution is relatively close to normal. We compared the RS method with both the LMS and the generalized additive models for location, scale and shape (GAMLSS) methods using simulated data and found that our method has smaller estimation error than the two existing methods. We also applied the new method to analyze height growth data from children being followed in a clinical observational study of growth hormone treatment, and compared the growth curves between those with growth disorders and the general population. Copyright © 2011 Elsevier Inc. All rights reserved.

  4. Callus Growth Kinetics of Physic Nut (Jatropha curcas L.) and Content of Fatty Acids from Crude Oil Obtained In Vitro.

    Science.gov (United States)

    da Luz Costa, Jefferson; da Silva, André Luís Lopes; Bier, Mário César Jucoski; Brondani, Gilvano Ebling; Gollo, André Luiz; Letti, Luiz Alberto Junior; Erasmo, Eduardo Andrea Lemus; Soccol, Carlos Ricardo

    2015-06-01

    The callus growth kinetics allows identifying the appropriate moment for callus pealing and monitoring the accumulation of primary and secondary metabolites. The physic nut (Jatropha curcas L.) is a plant species used for biofuel production due to its high oil content; however, this plant presents a great amount of bioactive compounds which can be useful for industry. The aim of this research was to establish a calli growth curve and to evaluate the fatty acid profile of crude oil extracted from callus. The callus growth kinetics presented a sigmoid standard curve with six distinct phases: lag, exponential, linear, deceleration, stationary, and decline. Total soluble sugars were higher at the inoculation day. Reducing sugars were higher at the inoculation day and at the 80th day. The highest percentage of ethereal extract (oil content) was obtained at the 120th day of culture, reaching 18 % of crude oil from the callus. The calli produced medium-chain and long-chain fatty acids (from 10 to 18 carbon atoms). The palmitic acid was the fatty acid with the highest proportion in oil (55.4 %). The lipid profile obtained in callus oil was different from the seed oil profile.

  5. Quantum effects on curve crossing in a Bose-Einstein condensate

    International Nuclear Information System (INIS)

    Yurovsky, V.A.; Ben-Reuven, A.; Julienne, P.S.

    2002-01-01

    Formation of atomic pairs by the dissociation of a molecular condensate or by inelastic collisions in an atomic condensate due to a time-dependent curve crossing process is studied beyond the mean-field approximation. The number of atoms formed by the spontaneous process is described by a Landau-Zener formula multiplied by an exponential amplification factor due to quantum many-body effects. Correlated atomic pairs are formed in squeezed states. The rate of stimulated processes depends on the relative phase of the two fields

  6. The McDonald exponentiated gamma distribution and its statistical properties

    OpenAIRE

    Al-Babtain, Abdulhakim A; Merovci, Faton; Elbatal, Ibrahim

    2015-01-01

    Abstract In this paper, we propose a five-parameter lifetime model called the McDonald exponentiated gamma distribution to extend beta exponentiated gamma, Kumaraswamy exponentiated gamma and exponentiated gamma, among several other models. We provide a comprehensive mathematical treatment of this distribution. We derive the moment generating function and the rth moment. We discuss estimation of the parameters by maximum likelihood and provide the information matrix. AMS Subject Classificatio...

  7. Exponential Stability of the Monotubular Heat Exchanger Equation with Time Delay in Boundary Observation

    Directory of Open Access Journals (Sweden)

    Xue-Lian Jin

    2017-01-01

    Full Text Available The exponential stability of the monotubular heat exchanger equation with boundary observation possessing a time delay and inner control was investigated. Firstly, the close-loop system was translated into an abstract Cauchy problem in the suitable state space. A uniformly bounded C0-semigroup generated by the close-loop system, which implies that the unique solution of the system exists, was shown. Secondly, the spectrum configuration of the closed-loop system was analyzed and the eventual differentiability and the eventual compactness of the semigroup were shown by the resolvent estimates on some resolvent sets. This implies that the spectrum-determined growth assumption holds. Finally, a sufficient condition, which is related to the physical parameters in the system and is independent of the time delay, of the exponential stability of the closed-loop system was given.

  8. Exponential Shear Flow of Linear, Entangled Polymeric Liquids

    DEFF Research Database (Denmark)

    Neergaard, Jesper; Park, Kyungho; Venerus, David C.

    2000-01-01

    A previously proposed reptation model is used to interpret exponential shear flow data taken on an entangled polystyrenesolution. Both shear and normal stress measurements are made during exponential shear using mechanical means. The model iscapable of explaining all trends seen in the data......, and suggests a novel analysis of the data. This analysis demonstrates thatexponential shearing flow is no more capable of stretching polymer chains than is inception of steady shear at comparableinstantaneous shear rates. In fact, all exponential shear flow stresses measured are bounded quantitatively...

  9. Dual exponential polynomials and linear differential equations

    Science.gov (United States)

    Wen, Zhi-Tao; Gundersen, Gary G.; Heittokangas, Janne

    2018-01-01

    We study linear differential equations with exponential polynomial coefficients, where exactly one coefficient is of order greater than all the others. The main result shows that a nontrivial exponential polynomial solution of such an equation has a certain dual relationship with the maximum order coefficient. Several examples illustrate our results and exhibit possibilities that can occur.

  10. A generalized-growth model to characterize the early ascending phase of infectious disease outbreaks

    DEFF Research Database (Denmark)

    Viboud, Cecile; Simonsen, Lone; Chowell, Gerardo

    2016-01-01

    the importance of sub-exponential growth for forecasting purposes.Results: We applied the generalized-growth model to 20 infectious disease outbreaks representing a range of transmission routes. We uncovered epidemic profiles ranging from very slow growth (p = 0.14 for the Ebola outbreak in Bomi, Liberia (2014...... African Ebola epidemic provided a unique opportunity to explore how growth profiles vary by geography; analysis of the largest district-level outbreaks revealed substantial growth variations (mean p = 0.59, range: 0.14–0.97). The districts of Margibi in Liberia and Bombali and Bo in Sierra Leone had near......-exponential growth, while the districts of Bomi in Liberia and Kenema in Sierra Leone displayed near constant incidences.Conclusions: Our findings reveal significant variation in epidemic growth patterns across different infectious disease outbreaks and highlights that sub-exponential growth is a common phenomenon...

  11. Equivalent dose determination in foraminifera: analytical description of the CO2--signal dose-response curve

    International Nuclear Information System (INIS)

    Hoffmann, D.; Woda, C.; Mangini, A.

    2003-01-01

    The dose-response of the CO 2 - signal (g=2.0006) in foraminifera with ages between 19 and 300 ka is investigated. The sum of two exponential saturation functions is an adequate function to describe the dose-response curve up to an additional dose of 8000 Gy. It yields excellent dating results but requires an artificial doses of at least 5000 Gy. For small additional doses of about 500 Gy the single exponential saturation function can be used to calculate a reliable equivalent dose D E , although it does not describ the dose-response for higher doses. The CO 2 - -signal dose-response indicates that the signal has two components of which one is less stable than the other

  12. Economic growth and environmental pollution in Myanmar: an analysis of environmental Kuznets curve.

    Science.gov (United States)

    Aung, Thiri Shwesin; Saboori, Behnaz; Rasoulinezhad, Ehsan

    2017-09-01

    This empirical study examines the short- and long-run relationship between GDP as an economic growth indicator and CO 2 emissions as an environmental pollution indicator in Myanmar by using annual time series data over the period of 1970-2014. It also carefully considered other proxies, such as trade openness, financial openness and urbanization, and structural breaks in the country. The fundamental objective of this study is to test the validity of environmental Kuznets curve (EKC) in the context of Myanmar. The dynamic estimates of the long- and short-term relationship among greenhouse gases (CO 2 , CH 4 , N 2 O), GDP, trade intensity, financial openness, and urbanization growth are built through an autoregressive distributed lag (ARDL) model. The empirical findings indicate that there is positive short- and long-run relationship between CO 2 and GDP and thus, no evidence of EKC hypothesis is found for CO 2 in Myanmar. Nevertheless, the existence of the EKC is observed for CH 4 and N 2 O. On the other hand, trade and financial openness have inverse relationship with CO 2 emissions. These results demonstrate that trade liberalization and financial openness will improve the environment quality in Myanmar in the long run.

  13. Periodic oscillation and exponential stability of delayed CNNs

    Science.gov (United States)

    Cao, Jinde

    2000-05-01

    Both the global exponential stability and the periodic oscillation of a class of delayed cellular neural networks (DCNNs) is further studied in this Letter. By applying some new analysis techniques and constructing suitable Lyapunov functionals, some simple and new sufficient conditions are given ensuring global exponential stability and the existence of periodic oscillatory solution of DCNNs. These conditions can be applied to design globally exponentially stable DCNNs and periodic oscillatory DCNNs and easily checked in practice by simple algebraic methods. These play an important role in the design and applications of DCNNs.

  14. Contribution of mono-exponential, bi-exponential and stretched exponential model-based diffusion-weighted MR imaging in the diagnosis and differentiation of uterine cervical carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Meng; Yu, Xiaoduo; Chen, Yan; Ouyang, Han; Zhou, Chunwu [Chinese Academy of Medical Sciences, Department of Diagnostic Radiology, Cancer Institute and Hospital, Peking Union Medical College, Beijing (China); Wu, Bing; Zheng, Dandan [GE MR Research China, Beijing (China)

    2017-06-15

    To investigate the potential of various metrics derived from mono-exponential model (MEM), bi-exponential model (BEM) and stretched exponential model (SEM)-based diffusion-weighted imaging (DWI) in diagnosing and differentiating the pathological subtypes and grades of uterine cervical carcinoma. 71 newly diagnosed patients with cervical carcinoma (50 cases of squamous cell carcinoma [SCC] and 21 cases of adenocarcinoma [AC]) and 32 healthy volunteers received DWI with multiple b values. The apparent diffusion coefficient (ADC), pure molecular diffusion (D), pseudo-diffusion coefficient (D*), perfusion fraction (f), water molecular diffusion heterogeneity index (alpha), and distributed diffusion coefficient (DDC) were calculated and compared between tumour and normal cervix, among different pathological subtypes and grades. All of the parameters were significantly lower in cervical carcinoma than normal cervical stroma except alpha. SCC showed lower ADC, D, f and DDC values and higher D* value than AC; D and DDC values of SCC and ADC and D values of AC were lower in the poorly differentiated group than those in the well-moderately differentiated group. Compared with MEM, diffusion parameters from BEM and SEM may offer additional information in cervical carcinoma diagnosis, predicting pathological tumour subtypes and grades, while f and D showed promising significance. (orig.)

  15. Modeling of alpha mass-efficiency curve

    International Nuclear Information System (INIS)

    Semkow, T.M.; Jeter, H.W.; Parsa, B.; Parekh, P.P.; Haines, D.K.; Bari, A.

    2005-01-01

    We present a model for efficiency of a detector counting gross α radioactivity from both thin and thick samples, corresponding to low and high sample masses in the counting planchette. The model includes self-absorption of α particles in the sample, energy loss in the absorber, range straggling, as well as detector edge effects. The surface roughness of the sample is treated in terms of fractal geometry. The model reveals a linear dependence of the detector efficiency on the sample mass, for low masses, as well as a power-law dependence for high masses. It is, therefore, named the linear-power-law (LPL) model. In addition, we consider an empirical power-law (EPL) curve, and an exponential (EXP) curve. A comparison is made of the LPL, EPL, and EXP fits to the experimental α mass-efficiency data from gas-proportional detectors for selected radionuclides: 238 U, 230 Th, 239 Pu, 241 Am, and 244 Cm. Based on this comparison, we recommend working equations for fitting mass-efficiency data. Measurement of α radioactivity from a thick sample can determine the fractal dimension of its surface

  16. Does proton decay follow the exponential law

    International Nuclear Information System (INIS)

    Sanchez-Gomez, J.L.; Alvarez-Estrada, R.F.; Fernandez, L.A.

    1984-01-01

    In this paper, we discuss the exponential law for proton decay. By using a simple model based upon SU(5)GUT and the current theories of hadron structure, we explicitely show that the corrections to the Wigner-Weisskopf approximation are quite negligible for present day protons, so that their eventual decay should follow the exponential law. Previous works are critically analyzed. (orig.)

  17. Exponential asymptotics of homoclinic snaking

    International Nuclear Information System (INIS)

    Dean, A D; Matthews, P C; Cox, S M; King, J R

    2011-01-01

    We study homoclinic snaking in the cubic-quintic Swift–Hohenberg equation (SHE) close to the onset of a subcritical pattern-forming instability. Application of the usual multiple-scales method produces a leading-order stationary front solution, connecting the trivial solution to the patterned state. A localized pattern may therefore be constructed by matching between two distant fronts placed back-to-back. However, the asymptotic expansion of the front is divergent, and hence should be truncated. By truncating optimally, such that the resultant remainder is exponentially small, an exponentially small parameter range is derived within which stationary fronts exist. This is shown to be a direct result of the 'locking' between the phase of the underlying pattern and its slowly varying envelope. The locking mechanism remains unobservable at any algebraic order, and can only be derived by explicitly considering beyond-all-orders effects in the tail of the asymptotic expansion, following the method of Kozyreff and Chapman as applied to the quadratic-cubic SHE (Chapman and Kozyreff 2009 Physica D 238 319–54, Kozyreff and Chapman 2006 Phys. Rev. Lett. 97 44502). Exponentially small, but exponentially growing, contributions appear in the tail of the expansion, which must be included when constructing localized patterns in order to reproduce the full snaking diagram. Implicit within the bifurcation equations is an analytical formula for the width of the snaking region. Due to the linear nature of the beyond-all-orders calculation, the bifurcation equations contain an analytically indeterminable constant, estimated in the previous work by Chapman and Kozyreff using a best fit approximation. A more accurate estimate of the equivalent constant in the cubic-quintic case is calculated from the iteration of a recurrence relation, and the subsequent analytical bifurcation diagram compared with numerical simulations, with good agreement

  18. Development of site index curves for Pinus kesiya in the Philippines ...

    African Journals Online (AJOL)

    Development of site index curves for Pinus kesiya in the Philippines. RIC Lumbres, YJ Lee, YO Seo, FG Calora JR. Abstract. This study was conducted to develop a height–age growth model and site index curves for site quality evaluation of old secondary-growth stands of Pinus kesiya in the northern Philippines.

  19. Economic growth and pollutant emissions in Tunisia. An empirical analysis of the environmental Kuznets curve

    Energy Technology Data Exchange (ETDEWEB)

    Fodha, Mouez [Paris School of Economics and CES, University Paris 1 Pantheon-Sorbonne, Maison des Sciences Economiques, 106-112 Bd de l' Hopital, 75647 Paris (France); Zaghdoud, Oussama [CES, University Paris 1 Pantheon-Sorbonne and Department of Economics, High School of Economic and Commercial Sciences of Tunis, 4 Rue Abou Zakaria El Hafsi, 1089 Montfleury (Tunisia)

    2010-02-15

    This paper investigates the relationship between economic growth and pollutant emissions for a small and open developing country, Tunisia, during the period 1961-2004. The investigation is made on the basis of the environmental Kuznets curve hypothesis, using time series data and cointegration analysis. Carbon dioxide (CO{sub 2}) and sulfur dioxide (SO{sub 2}) are used as the environmental indicators, and GDP as the economic indicator. Our results show that there is a long-run cointegrating relationship between the per capita emissions of two pollutants and the per capita GDP. An inverted U relationship between SO{sub 2} emissions and GDP has been found, with income turning point approximately equals to 1200 (constant 2000 prices) or to 3700 (in PPP, constant 2000 prices). However, a monotonically increasing relationship with GDP is found more appropriate for CO{sub 2} emissions. Furthermore, the causality results show that the relationship between income and pollution in Tunisia is one of unidirectional causality with income causing environmental changes and not vice versa, both in the short-run and long-run. This implies that an emission reduction policies and more investment in pollution abatement expense will not hurt economic growth. It could be a feasible policy tool for Tunisia to achieve its sustainable growth in the long-run. (author)

  20. Economic growth and pollutant emissions in Tunisia: An empirical analysis of the environmental Kuznets curve

    Energy Technology Data Exchange (ETDEWEB)

    Fodha, Mouez, E-mail: fodha@univ-paris1.f [Paris School of Economics and CES, University Paris 1 Pantheon-Sorbonne, Maison des Sciences Economiques, 106-112 Bd de l' Hopital, 75647 Paris (France); Zaghdoud, Oussama [CES, University Paris 1 Pantheon-Sorbonne and Department of Economics, High School of Economic and Commercial Sciences of Tunis, 4 Rue Abou Zakaria El Hafsi, 1089 Montfleury (Tunisia)

    2010-02-15

    This paper investigates the relationship between economic growth and pollutant emissions for a small and open developing country, Tunisia, during the period 1961-2004. The investigation is made on the basis of the environmental Kuznets curve hypothesis, using time series data and cointegration analysis. Carbon dioxide (CO{sub 2}) and sulfur dioxide (SO{sub 2}) are used as the environmental indicators, and GDP as the economic indicator. Our results show that there is a long-run cointegrating relationship between the per capita emissions of two pollutants and the per capita GDP. An inverted U relationship between SO{sub 2} emissions and GDP has been found, with income turning point approximately equals to $1200 (constant 2000 prices) or to $3700 (in PPP, constant 2000 prices). However, a monotonically increasing relationship with GDP is found more appropriate for CO{sub 2} emissions. Furthermore, the causality results show that the relationship between income and pollution in Tunisia is one of unidirectional causality with income causing environmental changes and not vice versa, both in the short-run and long-run. This implies that an emission reduction policies and more investment in pollution abatement expense will not hurt economic growth. It could be a feasible policy tool for Tunisia to achieve its sustainable growth in the long-run.

  1. Economic growth and pollutant emissions in Tunisia: An empirical analysis of the environmental Kuznets curve

    International Nuclear Information System (INIS)

    Fodha, Mouez; Zaghdoud, Oussama

    2010-01-01

    This paper investigates the relationship between economic growth and pollutant emissions for a small and open developing country, Tunisia, during the period 1961-2004. The investigation is made on the basis of the environmental Kuznets curve hypothesis, using time series data and cointegration analysis. Carbon dioxide (CO 2 ) and sulfur dioxide (SO 2 ) are used as the environmental indicators, and GDP as the economic indicator. Our results show that there is a long-run cointegrating relationship between the per capita emissions of two pollutants and the per capita GDP. An inverted U relationship between SO 2 emissions and GDP has been found, with income turning point approximately equals to $1200 (constant 2000 prices) or to $3700 (in PPP, constant 2000 prices). However, a monotonically increasing relationship with GDP is found more appropriate for CO 2 emissions. Furthermore, the causality results show that the relationship between income and pollution in Tunisia is one of unidirectional causality with income causing environmental changes and not vice versa, both in the short-run and long-run. This implies that an emission reduction policies and more investment in pollution abatement expense will not hurt economic growth. It could be a feasible policy tool for Tunisia to achieve its sustainable growth in the long-run.

  2. An integrated specification for the nexus of water pollution and economic growth in China: Panel cointegration, long-run causality and environmental Kuznets curve.

    Science.gov (United States)

    Zhang, Chen; Wang, Yuan; Song, Xiaowei; Kubota, Jumpei; He, Yanmin; Tojo, Junji; Zhu, Xiaodong

    2017-12-31

    This paper concentrates on a Chinese context and makes efforts to develop an integrated process to explicitly elucidate the relationship between economic growth and water pollution discharge-chemical oxygen demand (COD) discharge and ammonia nitrogen (NH 3 -N), using two unbalanced panel data sets covering the period separately from 1990 to 2014, and 2001 to 2014. In our present study, the panel unit root tests, cointegration tests, and Granger causality tests allowing for cross-sectional dependence, nonstationary, and heterogeneity are conducted to examine the causal effects of economic growth on COD/NH 3 -N discharge. Further, we simultaneously apply semi-parametric fixed effects estimation and parametric fixed effects estimation to investigate environmental Kuznets curve relationship for COD/NH 3 -N discharge. Our empirical results show a long-term bidirectional causality between economic growth and COD/NH 3 -N discharge in China. Within the Stochastic Impacts by Regression on Population, Affluence and Technology framework, we find evidence in support of an inverted U-shaped curved link between economic growth and COD/NH 3 -N discharge. To the best of our knowledge, there have not been any efforts made in investigating the nexus of economic growth and water pollution in such an integrated manner. Therefore, this study takes a fresh look on this topic. Copyright © 2017 Elsevier B.V. All rights reserved.

  3. The hyperbolic chemical bond: Fourier analysis of ground and first excited state potential energy curves of HX (X = H-Ne).

    Science.gov (United States)

    Harrison, John A

    2008-09-04

    RHF/aug-cc-pVnZ, UHF/aug-cc-pVnZ, and QCISD/aug-cc-pVnZ, n = 2-5, potential energy curves of H2 X (1) summation g (+) are analyzed by Fourier transform methods after transformation to a new coordinate system via an inverse hyperbolic cosine coordinate mapping. The Fourier frequency domain spectra are interpreted in terms of underlying mathematical behavior giving rise to distinctive features. There is a clear difference between the underlying mathematical nature of the potential energy curves calculated at the HF and full-CI levels. The method is particularly suited to the analysis of potential energy curves obtained at the highest levels of theory because the Fourier spectra are observed to be of a compact nature, with the envelope of the Fourier frequency coefficients decaying in magnitude in an exponential manner. The finite number of Fourier coefficients required to describe the CI curves allows for an optimum sampling strategy to be developed, corresponding to that required for exponential and geometric convergence. The underlying random numerical noise due to the finite convergence criterion is also a clearly identifiable feature in the Fourier spectrum. The methodology is applied to the analysis of MRCI potential energy curves for the ground and first excited states of HX (X = H-Ne). All potential energy curves exhibit structure in the Fourier spectrum consistent with the existence of resonances. The compact nature of the Fourier spectra following the inverse hyperbolic cosine coordinate mapping is highly suggestive that there is some advantage in viewing the chemical bond as having an underlying hyperbolic nature.

  4. Zeros and logarithmic asymptotics of Sobolev orthogonal polynomials for exponential weights

    Science.gov (United States)

    Díaz Mendoza, C.; Orive, R.; Pijeira Cabrera, H.

    2009-12-01

    We obtain the (contracted) weak zero asymptotics for orthogonal polynomials with respect to Sobolev inner products with exponential weights in the real semiaxis, of the form , with [gamma]>0, which include as particular cases the counterparts of the so-called Freud (i.e., when [phi] has a polynomial growth at infinity) and Erdös (when [phi] grows faster than any polynomial at infinity) weights. In addition, the boundness of the distance of the zeros of these Sobolev orthogonal polynomials to the convex hull of the support and, as a consequence, a result on logarithmic asymptotics are derived.

  5. Central Limit Theorem for Exponentially Quasi-local Statistics of Spin Models on Cayley Graphs

    Science.gov (United States)

    Reddy, Tulasi Ram; Vadlamani, Sreekar; Yogeshwaran, D.

    2018-04-01

    Central limit theorems for linear statistics of lattice random fields (including spin models) are usually proven under suitable mixing conditions or quasi-associativity. Many interesting examples of spin models do not satisfy mixing conditions, and on the other hand, it does not seem easy to show central limit theorem for local statistics via quasi-associativity. In this work, we prove general central limit theorems for local statistics and exponentially quasi-local statistics of spin models on discrete Cayley graphs with polynomial growth. Further, we supplement these results by proving similar central limit theorems for random fields on discrete Cayley graphs taking values in a countable space, but under the stronger assumptions of α -mixing (for local statistics) and exponential α -mixing (for exponentially quasi-local statistics). All our central limit theorems assume a suitable variance lower bound like many others in the literature. We illustrate our general central limit theorem with specific examples of lattice spin models and statistics arising in computational topology, statistical physics and random networks. Examples of clustering spin models include quasi-associated spin models with fast decaying covariances like the off-critical Ising model, level sets of Gaussian random fields with fast decaying covariances like the massive Gaussian free field and determinantal point processes with fast decaying kernels. Examples of local statistics include intrinsic volumes, face counts, component counts of random cubical complexes while exponentially quasi-local statistics include nearest neighbour distances in spin models and Betti numbers of sub-critical random cubical complexes.

  6. DNAzyme Feedback Amplification: Relaying Molecular Recognition to Exponential DNA Amplification.

    Science.gov (United States)

    Liu, Meng; Yin, Qingxin; McConnell, Erin M; Chang, Yangyang; Brennan, John D; Li, Yingfu

    2018-03-26

    Technologies capable of linking DNA amplification to molecular recognition are very desirable for ultrasensitive biosensing applications. We have developed a simple but powerful isothermal DNA amplification method, termed DNAzyme feedback amplification (DFA), that is capable of relaying molecular recognition to exponential DNA amplification. The method incorporates both an RNA-cleaving DNAzyme (RCD) and rolling circle amplification (RCA) carried out by a special DNA polymerase using a circular DNA template. DFA begins with a stimulus-dependent RCA reaction, producing tandemly linked RCDs in long-chain DNA products. These RCDs cleave an RNA-containing DNA sequence to form additional primers that hybridize to the circular DNA molecule, giving rise to DNA assemblies that act as the new inputs for RCA. The RCA reaction and the cleavage event keep on feeding each other autonomously, resulting in exponential growth of repetitive DNA sequences that can be easily detected. This method can be used for the detection of both nucleic acid based targets and non-nucleic acid analytes. In this article, we discuss the conceptual framework of the feedback amplification approach, the essential features of this method as well as remaining challenges and possible solutions. © 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  7. Global existence and exponential growth for a viscoelastic wave equation with dynamic boundary conditions

    KAUST Repository

    Gerbi, Sté phane; Said-Houari, Belkacem

    2013-01-01

    The goal of this work is to study a model of the wave equation with dynamic boundary conditions and a viscoelastic term. First, applying the Faedo-Galerkin method combined with the fixed point theorem, we show the existence and uniqueness of a local in time solution. Second, we show that under some restrictions on the initial data, the solution continues to exist globally in time. On the other hand, if the interior source dominates the boundary damping, then the solution is unbounded and grows as an exponential function. In addition, in the absence of the strong damping, then the solution ceases to exist and blows up in finite time.

  8. Global existence and exponential growth for a viscoelastic wave equation with dynamic boundary conditions

    KAUST Repository

    Gerbi, Stéphane

    2013-01-15

    The goal of this work is to study a model of the wave equation with dynamic boundary conditions and a viscoelastic term. First, applying the Faedo-Galerkin method combined with the fixed point theorem, we show the existence and uniqueness of a local in time solution. Second, we show that under some restrictions on the initial data, the solution continues to exist globally in time. On the other hand, if the interior source dominates the boundary damping, then the solution is unbounded and grows as an exponential function. In addition, in the absence of the strong damping, then the solution ceases to exist and blows up in finite time.

  9. Exponential Operators, Dobinski Relations and Summability

    International Nuclear Information System (INIS)

    Blasiak, P; Gawron, A; Horzela, A; Penson, K A; Solomon, A I

    2006-01-01

    We investigate properties of exponential operators preserving the particle number using combinatorial methods developed in order to solve the boson normal ordering problem. In particular, we apply generalized Dobinski relations and methods of multivariate Bell polynomials which enable us to understand the meaning of perturbation-like expansions of exponential operators. Such expansions, obtained as formal power series, are everywhere divergent but the Pade summation method is shown to give results which very well agree with exact solutions got for simplified quantum models of the one mode bosonic systems

  10. Exponential Data Fitting and its Applications

    CERN Document Server

    Pereyra, Victor

    2010-01-01

    Real and complex exponential data fitting is an important activity in many different areas of science and engineering, ranging from Nuclear Magnetic Resonance Spectroscopy and Lattice Quantum Chromodynamics to Electrical and Chemical Engineering, Vision and Robotics. The most commonly used norm in the approximation by linear combinations of exponentials is the l2 norm (sum of squares of residuals), in which case one obtains a nonlinear separable least squares problem. A number of different methods have been proposed through the years to solve these types of problems and new applications appear

  11. Exponentially tapered Josephson flux-flow oscillator

    DEFF Research Database (Denmark)

    Benabdallah, A.; Caputo, J. G.; Scott, Alwyn C.

    1996-01-01

    We introduce an exponentially tapered Josephson flux-flow oscillator that is tuned by applying a bias current to the larger end of the junction. Numerical and analytical studies show that above a threshold level of bias current the static solution becomes unstable and gives rise to a train...... of fluxons moving toward the unbiased smaller end, as in the standard flux-flow oscillator. An exponentially shaped junction provides several advantages over a rectangular junction including: (i) smaller linewidth, (ii) increased output power, (iii) no trapped flux because of the type of current injection...

  12. Environmental degradation, economic growth and energy consumption: Evidence of the environmental Kuznets curve in Malaysia

    International Nuclear Information System (INIS)

    Saboori, Behnaz; Sulaiman, Jamalludin

    2013-01-01

    This paper tests for the short and long-run relationship between economic growth, carbon dioxide (CO 2 ) emissions and energy consumption, using the Environmental Kuznets Curve (EKC) by employing both the aggregated and disaggregated energy consumption data in Malaysia for the period 1980–2009. The Autoregressive Distributed Lag (ARDL) methodology and Johansen–Juselius maximum likelihood approach were used to test the cointegration relationship; and the Granger causality test, based on the vector error correction model (VECM), to test for causality. The study does not support an inverted U-shaped relationship (EKC) when aggregated energy consumption data was used. When data was disaggregated based on different energy sources such as oil, coal, gas and electricity, the study does show evidences of the EKC hypothesis. The long-run Granger causality test shows that there is bi-directional causality between economic growth and CO 2 emissions, with coal, gas, electricity and oil consumption. This suggests that decreasing energy consumption such as coal, gas, electricity and oil appears to be an effective way to control CO 2 emissions but simultaneously will hinder economic growth. Thus suitable policies related to the efficient consumption of energy resources and consumption of renewable sources are required. - Highlights: • We investigated the EKC hypothesis by using Malaysian energy aggregated and disaggregated data. • It was found that the EKC is not supported, using the aggregated data (energy consumption). • However using disaggregated energy data (oil, coal and electricity) there is evidence of EKC. • Causality shows no causal relationship between economic growth and energy consumption in the short-run. • Economic growth Granger causes energy consumption and energy consumption causes CO 2 emissions in long-run

  13. Optimal Joint Detection and Estimation That Maximizes ROC-Type Curves.

    Science.gov (United States)

    Wunderlich, Adam; Goossens, Bart; Abbey, Craig K

    2016-09-01

    Combined detection-estimation tasks are frequently encountered in medical imaging. Optimal methods for joint detection and estimation are of interest because they provide upper bounds on observer performance, and can potentially be utilized for imaging system optimization, evaluation of observer efficiency, and development of image formation algorithms. We present a unified Bayesian framework for decision rules that maximize receiver operating characteristic (ROC)-type summary curves, including ROC, localization ROC (LROC), estimation ROC (EROC), free-response ROC (FROC), alternative free-response ROC (AFROC), and exponentially-transformed FROC (EFROC) curves, succinctly summarizing previous results. The approach relies on an interpretation of ROC-type summary curves as plots of an expected utility versus an expected disutility (or penalty) for signal-present decisions. We propose a general utility structure that is flexible enough to encompass many ROC variants and yet sufficiently constrained to allow derivation of a linear expected utility equation that is similar to that for simple binary detection. We illustrate our theory with an example comparing decision strategies for joint detection-estimation of a known signal with unknown amplitude. In addition, building on insights from our utility framework, we propose new ROC-type summary curves and associated optimal decision rules for joint detection-estimation tasks with an unknown, potentially-multiple, number of signals in each observation.

  14. Ranking Exponential Trapezoidal Fuzzy Numbers by Median Value

    Directory of Open Access Journals (Sweden)

    S. Rezvani

    2013-12-01

    Full Text Available In this paper, we want represented a method for ranking of two exponential trapezoidal fuzzy numbers. A median value is proposed for the ranking of exponential trapezoidal fuzzy numbers. For the validation the results of the proposed approach are compared with different existing approaches.

  15. Exponentiation for products of Wilson lines within the generating function approach

    International Nuclear Information System (INIS)

    Vladimirov, A.A.

    2015-01-01

    We present the generating function approach to the perturbative exponentiation of correlators of a product of Wilson lines and loops. The exponentiated expression is presented in closed form as an algebraic function of correlators of known operators, which can be seen as a generating function for web diagrams. The expression is naturally split onto two parts: the exponentiation kernel, which accumulates all non-trivial information about web diagrams, and the defect of exponentiation, which reconstructs the matrix exponent and is a function of the exponentiation kernel. The detailed comparison of the presented approach with existing approaches to exponentiation is presented as well. We also give examples of calculations within the generating function exponentiation, namely, we consider different configurations of light-like Wilson lines in the multi-gluon-exchange-webs (MGEW) approximation. Within this approximation the corresponding correlators can be calculated exactly at any order of perturbative expansion by only algebraic manipulations. The MGEW approximation shows violation of the dipole formula for infrared singularities at three-loop order.

  16. A semi-analytical three-dimensional free vibration analysis of functionally graded curved panels

    Energy Technology Data Exchange (ETDEWEB)

    Zahedinejad, P. [Department of Mechanical Engineering, Islamic Azad University, Branch of Shiraz, Shiraz (Iran, Islamic Republic of); Malekzadeh, P., E-mail: malekzadeh@pgu.ac.i [Department of Mechanical Engineering, Persian Gulf University, Persian Gulf University Boulevard, Bushehr 75168 (Iran, Islamic Republic of); Center of Excellence for Computational Mechanics, Shiraz University, Shiraz (Iran, Islamic Republic of); Farid, M. [Department of Mechanical Engineering, Islamic Azad University, Branch of Shiraz, Shiraz (Iran, Islamic Republic of); Karami, G. [Department of Mechanical Engineering and Applied Mechanics, North Dakota State University, Fargo, ND 58105-5285 (United States)

    2010-08-15

    Based on the three-dimensional elasticity theory, free vibration analysis of functionally graded (FG) curved thick panels under various boundary conditions is studied. Panel with two opposite edges simply supported and arbitrary boundary conditions at the other edges are considered. Two different models of material properties variations based on the power law distribution in terms of the volume fractions of the constituents and the exponential distribution of the material properties through the thickness are considered. Differential quadrature method in conjunction with the trigonometric functions is used to discretize the governing equations. With a continuous material properties variation assumption through the thickness of the curved panel, differential quadrature method is efficiently used to discretize the governing equations and to implement the related boundary conditions at the top and bottom surfaces of the curved panel and in strong form. The convergence of the method is demonstrated and to validate the results, comparisons are made with the solutions for isotropic and FG curved panels. By examining the results of thick FG curved panels for various geometrical and material parameters and subjected to different boundary conditions, the influence of these parameters and in particular, those due to functionally graded material parameters are studied.

  17. Effects of Exponential Trends on Correlations of Stock Markets

    Directory of Open Access Journals (Sweden)

    Ai-Jing Lin

    2014-01-01

    Full Text Available Detrended fluctuation analysis (DFA is a scaling analysis method used to estimate long-range power-law correlation exponents in time series. In this paper, DFA is employed to discuss the long-range correlations of stock market. The effects of exponential trends on correlations of Hang Seng Index (HSI are investigated with emphasis. We find that the long-range correlations and the positions of the crossovers of lower order DFA appear to have no immunity to the additive exponential trends. Further, our analysis suggests that an increase in the DFA order increases the efficiency of eliminating on exponential trends. In addition, the empirical study shows that the correlations and crossovers are associated with DFA order and magnitude of exponential trends.

  18. Establishment of Uropygial Gland Growth Curves for White, Three-Way Crossed Mule Ducklings

    Directory of Open Access Journals (Sweden)

    YH Chen

    2015-06-01

    Full Text Available Growth curves for the uropygial gland (UG of white, 3-way crossed mule ducklings were established using the Gompertz function. In total, 144 ducklings were fed in 12 floor pens with 12 birds in each pen. Each pen contained an equal number of animals of each sex. Feed and water were supplied ad libitumthroughout the entire experimental period. The weekly change in UG weight was recorded in males and females from hatch to 8 weeks of age. The weight and length of the UG, the width of the lobus glandulae uropygialis, the length and width of the pluma of the circulus uropygialis, and the index of the papilla uropygialis were measured once a week in individual ducklings in one pen. The average UG weight gain observed in white, 3-way crossed drakes was significantly higher than that of ducks of 21-56 days of age (P< 0.05. The UG length was 1.64-2.23 times the width of the left or right lobe, and the development of the UG was delayed from 3-4 weeks of age. The morphology of the UG changed from elliptical to elongated-elliptical with age. The right and left lobus glandulae uropygialis were symmetrical. The Gompertz growth functions of the UG in drakes and ducks were W=5.49e-e-0.675(t-1.955 and W=4.76e-e-0.685(t-1.936, respectively, where t represents age in weeks. These equations indicated that the maximum growth rate for drakes occurred at 14.1 days of age and for ducks at 13.6 days of age.

  19. Exponential integrators in time-dependent density-functional calculations

    Science.gov (United States)

    Kidd, Daniel; Covington, Cody; Varga, Kálmán

    2017-12-01

    The integrating factor and exponential time differencing methods are implemented and tested for solving the time-dependent Kohn-Sham equations. Popular time propagation methods used in physics, as well as other robust numerical approaches, are compared to these exponential integrator methods in order to judge the relative merit of the computational schemes. We determine an improvement in accuracy of multiple orders of magnitude when describing dynamics driven primarily by a nonlinear potential. For cases of dynamics driven by a time-dependent external potential, the accuracy of the exponential integrator methods are less enhanced but still match or outperform the best of the conventional methods tested.

  20. The Impact of Student Teaching Experience on Pre-Service Teachers' Readiness for Technology Integration: A Mixed Methods Study with Growth Curve Modeling

    Science.gov (United States)

    Sun, Yan; Strobel, Johannes; Newby, Timothy J.

    2017-01-01

    Adopting a two-phase explanatory sequential mixed methods research design, the current study examined the impact of student teaching experiences on pre-service teachers' readiness for technology integration. In phase-1 of quantitative investigation, 2-level growth curve models were fitted using online repeated measures survey data collected from…

  1. Confronting quasi-exponential inflation with WMAP seven

    International Nuclear Information System (INIS)

    Pal, Barun Kumar; Pal, Supratik; Basu, B.

    2012-01-01

    We confront quasi-exponential models of inflation with WMAP seven years dataset using Hamilton Jacobi formalism. With a phenomenological Hubble parameter, representing quasi exponential inflation, we develop the formalism and subject the analysis to confrontation with WMAP seven using the publicly available code CAMB. The observable parameters are found to fair extremely well with WMAP seven. We also obtain a ratio of tensor to scalar amplitudes which may be detectable in PLANCK

  2. Rethinking the Concept of Long-Run Economic Growth

    DEFF Research Database (Denmark)

    Groth, Christian; Koch, Karl-Josef; Steger, Thomas Michael

    This paper argues that growth theory needs a more general "regularity" concept than that of exponential growth. This offers the possibility of considering a richer set of parameter combinations than in standard growth models. Allowing zero population growth in the Jones (1995) model serves as our...

  3. Blowing-up semilinear wave equation with exponential nonlinearity ...

    Indian Academy of Sciences (India)

    H1-norm. Hence, it is legitimate to consider an exponential nonlinearity. Moreover, the choice of an exponential nonlinearity emerges from a possible control of solutions via a. Moser–Trudinger type inequality [1, 16, 19]. In fact, Nakamura and Ozawa [17] proved global well-posedness and scattering for small Cauchy data in ...

  4. Accounting for inherent variability of growth in microbial risk assessment.

    Science.gov (United States)

    Marks, H M; Coleman, M E

    2005-04-15

    Risk assessments of pathogens need to account for the growth of small number of cells under varying conditions. In order to determine the possible risks that occur when there are small numbers of cells, stochastic models of growth are needed that would capture the distribution of the number of cells over replicate trials of the same scenario or environmental conditions. This paper provides a simple stochastic growth model, accounting only for inherent cell-growth variability, assuming constant growth kinetic parameters, for an initial, small, numbers of cells assumed to be transforming from a stationary to an exponential phase. Two, basic, microbial sets of assumptions are considered: serial, where it is assume that cells transform through a lag phase before entering the exponential phase of growth; and parallel, where it is assumed that lag and exponential phases develop in parallel. The model is based on, first determining the distribution of the time when growth commences, and then modelling the conditional distribution of the number of cells. For the latter distribution, it is found that a Weibull distribution provides a simple approximation to the conditional distribution of the relative growth, so that the model developed in this paper can be easily implemented in risk assessments using commercial software packages.

  5. Extending World Health Organization weight-for-age reference curves to older children.

    Science.gov (United States)

    Rodd, Celia; Metzger, Daniel L; Sharma, Atul

    2014-02-03

    For ages 5-19 years, the World Health Organization (WHO) publishes reference charts based on 'core data' from the US National Center for Health Statistics (NCHS), collected from 1963-75 on 22,917 US children. To promote the use of body mass index in older children, weight-for-age was omitted after age 10. Health providers have subsequently expressed concerns about this omission and the selection of centiles. We therefore sought to extend weight-for-age reference curves from 10 to 19 years by applying WHO exclusion criteria and curve fitting methods to the core NCHS data and to revise the choice of displayed centiles. WHO analysts first excluded ~ 3% of their reference population in order to achieve a "non-obese sample with equal height". Based on these exclusion criteria, 314 girls and 304 boys were first omitted for 'unhealthy' weights-for-height. By applying WHO global deviance and information criteria, optimal Box-Cox power exponential models were used to fit smoothed weight-for-age centiles. Bootstrap resampling was used to assess the precision of centile estimates. For all charts, additional centiles were included in the healthy range (3 to 97%), and the more extreme WHO centiles 0.1 and 99.9% were dropped. In addition to weight-for-age beyond 10 years, our charts provide more granularity in the centiles in the healthy range -2 to +2 SD (3-97%). For both weight and BMI, the bootstrap confidence intervals for the 99.9th centile were at least an order of magnitude wider than the corresponding 50th centile values. These charts complement existing WHO charts by allowing weight-for-age to be plotted concurrently with height in older children. All modifications followed strict WHO methodology and utilized the same core data from the US NCHS. The additional centiles permit a more precise assessment of normal growth and earlier detection of aberrant growth as it crosses centiles. Elimination of extreme centiles reduces the risk of misclassification. A complete set of

  6. Research on industrialization of electric vehicles with its demand forecast using exponential smoothing method

    Directory of Open Access Journals (Sweden)

    Zhanglin Peng

    2015-04-01

    Full Text Available Purpose: Electric vehicles industry has gotten a rapid development in the world, especially in the developed countries, but still has a gap among different countries or regions. The advanced industrialization experiences of the EVs in the developed countries will have a great helpful for the development of EVs industrialization in the developing countries. This paper seeks to research the industrialization path & prospect of American EVs by forecasting electric vehicles demand and its proportion to the whole car sales based on the historical 37 EVs monthly sales and Cars monthly sales spanning from Dec. 2010 to Dec. 2013, and find out the key measurements to help Chinese government and automobile enterprises to promote Chinese EVs industrialization. Design/methodology: Compared with Single Exponential Smoothing method and Double Exponential Smoothing method, Triple exponential smoothing method is improved and applied in this study. Findings: The research results show that:  American EVs industry will keep a sustained growth in the next 3 months.  Price of the EVs, price of fossil oil, number of charging station, EVs technology and the government market & taxation polices have a different influence to EVs sales. So EVs manufacturers and policy-makers can adjust or reformulate some technology tactics and market measurements according to the forecast results. China can learn from American EVs polices and measurements to develop Chinese EVs industry. Originality/value: The main contribution of this paper is to use the triple exponential smoothing method to forecast the electric vehicles demand and its proportion to the whole automobile sales, and analyze the industrial development of Chinese electric vehicles by American EVs industry.

  7. (Anti)symmetric multivariate exponential functions and corresponding Fourier transforms

    International Nuclear Information System (INIS)

    Klimyk, A U; Patera, J

    2007-01-01

    We define and study symmetrized and antisymmetrized multivariate exponential functions. They are defined as determinants and antideterminants of matrices whose entries are exponential functions of one variable. These functions are eigenfunctions of the Laplace operator on the corresponding fundamental domains satisfying certain boundary conditions. To symmetric and antisymmetric multivariate exponential functions there correspond Fourier transforms. There are three types of such Fourier transforms: expansions into the corresponding Fourier series, integral Fourier transforms and multivariate finite Fourier transforms. Eigenfunctions of the integral Fourier transforms are found

  8. The many faces of the quantum Liouville exponentials

    Science.gov (United States)

    Gervais, Jean-Loup; Schnittger, Jens

    1994-01-01

    First, it is proven that the three main operator approaches to the quantum Liouville exponentials—that is the one of Gervais-Neveu (more recently developed further by Gervais), Braaten-Curtright-Ghandour-Thorn, and Otto-Weigt—are equivalent since they are related by simple basis transformations in the Fock space of the free field depending upon the zero-mode only. Second, the GN-G expressions for quantum Liouville exponentials, where the U q( sl(2)) quantum-group structure is manifest, are shown to be given by q-binomial sums over powers of the chiral fields in the J = {1}/{2} representation. Third, the Liouville exponentials are expressed as operator tau functions, whose chiral expansion exhibits a q Gauss decomposition, which is the direct quantum analogue of the classical solution of Leznov and Saveliev. It involves q exponentials of quantum-group generators with group "parameters" equal to chiral components of the quantum metric. Fourth, we point out that the OPE of the J = {1}/{2} Liouville exponential provides the quantum version of the Hirota bilinear equation.

  9. Geometry of q-Exponential Family of Probability Distributions

    Directory of Open Access Journals (Sweden)

    Shun-ichi Amari

    2011-06-01

    Full Text Available The Gibbs distribution of statistical physics is an exponential family of probability distributions, which has a mathematical basis of duality in the form of the Legendre transformation. Recent studies of complex systems have found lots of distributions obeying the power law rather than the standard Gibbs type distributions. The Tsallis q-entropy is a typical example capturing such phenomena. We treat the q-Gibbs distribution or the q-exponential family by generalizing the exponential function to the q-family of power functions, which is useful for studying various complex or non-standard physical phenomena. We give a new mathematical structure to the q-exponential family different from those previously given. It has a dually flat geometrical structure derived from the Legendre transformation and the conformal geometry is useful for understanding it. The q-version of the maximum entropy theorem is naturally induced from the q-Pythagorean theorem. We also show that the maximizer of the q-escort distribution is a Bayesian MAP (Maximum A posteriori Probability estimator.

  10. Kullback-Leibler divergence and the Pareto-Exponential approximation.

    Science.gov (United States)

    Weinberg, G V

    2016-01-01

    Recent radar research interests in the Pareto distribution as a model for X-band maritime surveillance radar clutter returns have resulted in analysis of the asymptotic behaviour of this clutter model. In particular, it is of interest to understand when the Pareto distribution is well approximated by an Exponential distribution. The justification for this is that under the latter clutter model assumption, simpler radar detection schemes can be applied. An information theory approach is introduced to investigate the Pareto-Exponential approximation. By analysing the Kullback-Leibler divergence between the two distributions it is possible to not only assess when the approximation is valid, but to determine, for a given Pareto model, the optimal Exponential approximation.

  11. Mathematical modelling of the growth of human fetus anatomical structures.

    Science.gov (United States)

    Dudek, Krzysztof; Kędzia, Wojciech; Kędzia, Emilia; Kędzia, Alicja; Derkowski, Wojciech

    2017-09-01

    The goal of this study was to present a procedure that would enable mathematical analysis of the increase of linear sizes of human anatomical structures, estimate mathematical model parameters and evaluate their adequacy. Section material consisted of 67 foetuses-rectus abdominis muscle and 75 foetuses- biceps femoris muscle. The following methods were incorporated to the study: preparation and anthropologic methods, image digital acquisition, Image J computer system measurements and statistical analysis method. We used an anthropologic method based on age determination with the use of crown-rump length-CRL (V-TUB) by Scammon and Calkins. The choice of mathematical function should be based on a real course of the curve presenting growth of anatomical structure linear size Ύ in subsequent weeks t of pregnancy. Size changes can be described with a segmental-linear model or one-function model with accuracy adequate enough for clinical purposes. The interdependence of size-age is described with many functions. However, the following functions are most often considered: linear, polynomial, spline, logarithmic, power, exponential, power-exponential, log-logistic I and II, Gompertz's I and II and von Bertalanffy's function. With the use of the procedures described above, mathematical models parameters were assessed for V-PL (the total length of body) and CRL body length increases, rectus abdominis total length h, its segments hI, hII, hIII, hIV, as well as biceps femoris length and width of long head (LHL and LHW) and of short head (SHL and SHW). The best adjustments to measurement results were observed in the exponential and Gompertz's models.

  12. Relating species abundance distributions to species-area curves in two Mediterranean-type shrublands

    Science.gov (United States)

    Keeley, Jon E.

    2003-01-01

    Based on both theoretical and empirical studies there is evidence that different species abundance distributions underlie different species-area relationships. Here I show that Australian and Californian shrubland communities (at the scale from 1 to 1000 m2) exhibit different species-area relationships and different species abundance patterns. The species-area relationship in Australian heathlands best fits an exponential model and species abundance (based on both density and cover) follows a narrow log normal distribution. In contrast, the species-area relationship in Californian shrublands is best fit with the power model and, although species abundance appears to fit a log normal distribution, the distribution is much broader than in Australian heathlands. I hypothesize that the primary driver of these differences is the abundance of small-stature annual species in California and the lack of annuals in Australian heathlands. Species-area is best fit by an exponential model in Australian heathlands because the bulk of the species are common and thus the species-area curves initially rise rapidly between 1 and 100 m2. Annuals in Californian shrublands generate very broad species abundance distributions with many uncommon or rare species. The power function is a better model in these communities because richness increases slowly from 1 to 100 m2 but more rapidly between 100 and 1000 m2due to the abundance of rare or uncommon species that are more likely to be encountered at coarser spatial scales. The implications of this study are that both the exponential and power function models are legitimate representations of species-area relationships in different plant communities. Also, structural differences in community organization, arising from different species abundance distributions, may lead to different species-area curves, and this may be tied to patterns of life form distribution.

  13. Evolution of defects in a multicomponent glass irradiated by 1 MeV electrons

    International Nuclear Information System (INIS)

    Wang Qingyan; Geng Hongbin; Sun Chengyue; Zhang Zhonghua; He Shiyu

    2010-01-01

    The optical properties and microstructural degradation of a multicomponent glass after exposure to 1 MeV electrons for fluences of 10 13 to 10 16 e - /cm 2 , as well as the recovery during annealing at room temperature (RT) for the fluence of 10 16 e - /cm 2 , are investigated. The non-bridging oxygen hole centers (NBOHCs), as well as trapped electrons (TEs), are mainly attributed to optical absorption bands and paramagnetic spectra. In comparison of the exponential curves, the in-growth kinetics for each type of defect with increasing fluence are separable, and a new linearly-combined exponential model is used to describe the structural responses during irradiation. Accordingly, RT bleaching curves of defects follow a linearly-combined exponential decay function. Consistent results from optical and paramagnetic signals suggest that this linearly-combined model provides a reasonable kinetic description of the growth and bleaching process of defects.

  14. Is the basic law of radioactive decay exponential?

    International Nuclear Information System (INIS)

    Gopych, P.M.; Zalyubovskii, I.I.

    1988-01-01

    Basic theoretical approaches to the explanation of the observed exponential nature of the decay law are discussed together with the hypothesis that it is not exponential. The significance of this question and its connection with fundamental problems of modern physics are considered. The results of experiments relating to investigation of the form of the decay law are given

  15. Growth in Adolescent Self-Regulation and Impact on Sexual Risk-Taking: A Curve-of-Factors Analysis.

    Science.gov (United States)

    Crandall, AliceAnn; Magnusson, Brianna M; Novilla, M Lelinneth B

    2018-04-01

    Adolescent self-regulation is increasingly seen as an important predictor of sexual risk-taking behaviors, but little is understood about how changes in self-regulation affect later sexual risk-taking. Family financial stress may affect the development of self-regulation and later engagement in sexual risk-taking. We examined whether family financial stress influences self-regulation in early adolescence (age 13) and growth in self-regulation throughout adolescence (from age 13-17 years). We then assessed the effects of family financial stress, baseline self-regulation, and the development of self-regulation on adolescent sexual risk-taking behaviors at age 18 years. Using a curve-of-factors model, we examined these relationships in a 6-year longitudinal study of 470 adolescents (52% female) and their parents from a large northwestern city in the United States. Results indicated that family financial stress was negatively associated with baseline self-regulation but not with growth in self-regulation throughout adolescence. Both baseline self-regulation and growth in self-regulation were predictive of decreased likelihood of engaging in sexual risk-taking. Family financial stress was not predictive of later sexual risk-taking. Intervening to support the development of self-regulation in adolescence may be especially protective against later sexual risk-taking.

  16. Laminar phase flow for an exponentially tapered Josephson oscillator

    DEFF Research Database (Denmark)

    Benabdallah, A.; Caputo, J. G.; Scott, Alwyn C.

    2000-01-01

    Exponential tapering and inhomogeneous current feed were recently proposed as means to improve the performance of a Josephson flux flow oscillator. Extensive numerical results backed up by analysis are presented here that support this claim and demonstrate that exponential tapering reduces...... the small current instability region and leads to a laminar flow regime where the voltage wave form is periodic giving the oscillator minimal spectral width. Tapering also leads to an increased output power. Since exponential tapering is not expected to increase the difficulty of fabricating a flux flow...

  17. Calorimeter prediction based on multiple exponentials

    International Nuclear Information System (INIS)

    Smith, M.K.; Bracken, D.S.

    2002-01-01

    Calorimetry allows very precise measurements of nuclear material to be carried out, but it also requires relatively long measurement times to do so. The ability to accurately predict the equilibrium response of a calorimeter would significantly reduce the amount of time required for calorimetric assays. An algorithm has been developed that is effective at predicting the equilibrium response. This multi-exponential prediction algorithm is based on an iterative technique using commercial fitting routines that fit a constant plus a variable number of exponential terms to calorimeter data. Details of the implementation and the results of trials on a large number of calorimeter data sets will be presented

  18. Exponential convergence on a continuous Monte Carlo transport problem

    International Nuclear Information System (INIS)

    Booth, T.E.

    1997-01-01

    For more than a decade, it has been known that exponential convergence on discrete transport problems was possible using adaptive Monte Carlo techniques. An adaptive Monte Carlo method that empirically produces exponential convergence on a simple continuous transport problem is described

  19. Stochastic B-series and order conditions for exponential integrators

    DEFF Research Database (Denmark)

    Arara, Alemayehu Adugna; Debrabant, Kristian; Kværnø, Anne

    2018-01-01

    We discuss stochastic differential equations with a stiff linear part and their approximation by stochastic exponential integrators. Representing the exact and approximate solutions using B-series and rooted trees, we derive the order conditions for stochastic exponential integrators. The resulting...

  20. Some fundamental questions about R-curves

    International Nuclear Information System (INIS)

    Kolednik, O.

    1992-01-01

    With the help of two simple thought experiments it is demonstrated that there exist two physically different types of fracture toughness. The crack-growth toughness, which is identical to the Griffith crack growth resistance, R, is a measure of the non-reversible energy which is needed to produce an increment of new crack area. The size of R is reflected by the slopes of the R-curves commonly used. So an increasing J-Δa-curve does not mean that the crack-growth resistance increases. The fracture initiation toughness, J i , is a normalized total energy (related to the ligament area) which must be put into the specimen up to fracture initiation. Only for ideally brittle materials R and J i have equal sizes. For small-scale yielding a relationship exists between R and J i , ao a one-parameter description of fracture processes is applicable. For large-scale yielding R and J i are not strictly related and both parameters are necessary to describe the fracture process. (orig.) [de

  1. Effect of algal growth phase on Aureococcus anophagefferens susceptibility to hydrogen peroxide

    International Nuclear Information System (INIS)

    Randhawa, Varunpreet; Thakkar, Megha; Wei, Liping

    2013-01-01

    Highlights: •Brown tide alga's susceptibility to H 2 O 2 was examined via growth and physiology responses. •The study was designed equalizing the influence of the media and cell density in test cultures. •Stationary cells was more sensitive to H 2 O 2 than exponential cells. •Stationary cells showed weaker non-protein thiol up-regulation than exponential cells. •Stationary cells mediated greater H 2 O 2 decomposition than exponential cells did. -- Abstract: A cell's growth phase could affect its susceptibility to a biocide in microbial control. This study examines the growth phase dependent susceptibility of a brown tide bloom alga Aureococcus anophagefferens to microbial biocide hydrogen peroxide (H 2 O 2 ). Test cultures of A. anophagefferens cells in exponential and stationary growth phase and similar initial cell density (1.6 × 10 6 cells mL −1 ) were exposed to 0.4–1.6 mg L −1 H 2 O 2 . Changes in algal growth (in vivo fluorescence, total chlorophyll a, and cell density), cell physiology (maximum quantum yield of photosystem II, and total intracellular non-protein thiols), and H 2 O 2 decomposition were quantified. Results show that the stationary phase cells are more susceptible to H 2 O 2 than the exponential phase cells, and this is attributed to the weaker ROS (reactive oxygen species) scavenging system and consequently greater cell damage in stationary phase cells. The stationary phase cells potentially require 30–40% less H 2 O 2 to reach 90% removal within 12 h of treatment as compared to the exponential phase cells. The results have practical implications in brown tide bloom control with respect to the timing and the dosage of H 2 O 2 application

  2. Analysis of growth characteristics in short-term divergently selected ...

    African Journals Online (AJOL)

    weeks of age body weight in divergent lines of Japanese quail. Growth curves for both sexes within each selection group resembled the general sigmoid shape of a typical growth curve. Gompertz model curves and the observed growth curves were ...

  3. Sampling from the normal and exponential distributions

    International Nuclear Information System (INIS)

    Chaplin, K.R.; Wills, C.A.

    1982-01-01

    Methods for generating random numbers from the normal and exponential distributions are described. These involve dividing each function into subregions, and for each of these developing a method of sampling usually based on an acceptance rejection technique. When sampling from the normal or exponential distribution, each subregion provides the required random value with probability equal to the ratio of its area to the total area. Procedures written in FORTRAN for the CYBER 175/CDC 6600 system are provided to implement the two algorithms

  4. Exponential stability of delayed fuzzy cellular neural networks with diffusion

    International Nuclear Information System (INIS)

    Huang Tingwen

    2007-01-01

    The exponential stability of delayed fuzzy cellular neural networks (FCNN) with diffusion is investigated. Exponential stability, significant for applications of neural networks, is obtained under conditions that are easily verified by a new approach. Earlier results on the exponential stability of FCNN with time-dependent delay, a special case of the model studied in this paper, are improved without using the time-varying term condition: dτ(t)/dt < μ

  5. Accelerating cosmologies from exponential potentials

    International Nuclear Information System (INIS)

    Neupane, Ishwaree P.

    2003-11-01

    It is learnt that exponential potentials of the form V ∼ exp(-2cφ/M p ) arising from the hyperbolic or flux compactification of higher-dimensional theories are of interest for getting short periods of accelerated cosmological expansions. Using a similar potential but derived for the combined case of hyperbolic-flux compactification, we study a four-dimensional flat (or open) FRW cosmologies and give analytic (and numerical) solutions with exponential behavior of scale factors. We show that, for the M-theory motivated potentials, the cosmic acceleration of the universe can be eternal if the spatial curvature of the 4d spacetime is negative, while the acceleration is only transient for a spatially flat universe. We also briefly discuss about the mass of massive Kaluza-Klein modes and the dynamical stabilization of the compact hyperbolic extra dimensions. (author)

  6. Results of Casting in Severe Curves in Infantile Scoliosis.

    Science.gov (United States)

    Stasikelis, Peter J; Carpenter, Ashley M

    2018-04-01

    Previous work has demonstrated best results for casting in infantile scoliosis when the curves are small and the child begins casting under 2 years of age. This study examines if casting can delay the need for growth friendly instrumentation in severe curves (50 to 106 degrees) and how the comorbidities of syrinx or genetic syndromes affected outcomes. All children undergoing casting for scoliosis at a single institution over an 8-year period were examined. Inclusion criteria included initial curve at first casting of ≥50 degrees, age ≤3 years at the start of casting, and a minimum follow-up of 3 years. Of 148 children undergoing casting during this period, 44 met our inclusion criteria. All children underwent magnetic resonance imaging. Ten children with a syrinx were identified. Ten children had known genetic syndromes (2 who also had a syrinx). The 26 children without these comorbidities were considered idiopathic. Curve magnitude ranged from 50 to 106 degrees. Nine of the 26 (35%) children in the children with idiopathic curves demonstrated resolution of their curves, while only 3 of the remaining 18 (17%) did. Of the children that did not have resolution of their curves, 14 were maintained over the entire follow-up period to within 15 degrees of their initial curve and 13 were improved 15 degrees or more. Only 5 children had an increase of 15 degrees or more over the follow-up period and 4 of these have undergone growth friendly instrumentation after a mean delay from initial cast of 71 months (range, 18 to 100 mo). This study demonstrates that even in severe curves, casting was effective in delaying instrumentation in all cases, and led to curve resolution of the curves in 12 of 44 children. Level III-case control study.

  7. Three-Step Predictor-Corrector of Exponential Fitting Method for Nonlinear Schroedinger Equations

    International Nuclear Information System (INIS)

    Tang Chen; Zhang Fang; Yan Haiqing; Luo Tao; Chen Zhanqing

    2005-01-01

    We develop the three-step explicit and implicit schemes of exponential fitting methods. We use the three-step explicit exponential fitting scheme to predict an approximation, then use the three-step implicit exponential fitting scheme to correct this prediction. This combination is called the three-step predictor-corrector of exponential fitting method. The three-step predictor-corrector of exponential fitting method is applied to numerically compute the coupled nonlinear Schroedinger equation and the nonlinear Schroedinger equation with varying coefficients. The numerical results show that the scheme is highly accurate.

  8. Assessing Trust and Effectiveness in Virtual Teams: Latent Growth Curve and Latent Change Score Models

    Directory of Open Access Journals (Sweden)

    Michael D. Coovert

    2017-08-01

    Full Text Available Trust plays a central role in the effectiveness of work groups and teams. This is the case for both face-to-face and virtual teams. Yet little is known about the development of trust in virtual teams. We examined cognitive and affective trust and their relationship to team effectiveness as reflected through satisfaction with one’s team and task performance. Latent growth curve analysis reveals both trust types start at a significant level with individual differences in that initial level. Cognitive trust follows a linear growth pattern while affective trust is overall non-linear, but becomes linear once established. Latent change score models are utilized to examine change in trust and also its relationship with satisfaction with the team and team performance. In examining only change in trust and its relationship to satisfaction there appears to be a straightforward influence of trust on satisfaction and satisfaction on trust. However, when incorporated into a bivariate coupling latent change model the dynamics of the relationship are revealed. A similar pattern holds for trust and task performance; however, in the bivariate coupling change model a more parsimonious representation is preferred.

  9. Global robust exponential stability analysis for interval recurrent neural networks

    International Nuclear Information System (INIS)

    Xu Shengyuan; Lam, James; Ho, Daniel W.C.; Zou Yun

    2004-01-01

    This Letter investigates the problem of robust global exponential stability analysis for interval recurrent neural networks (RNNs) via the linear matrix inequality (LMI) approach. The values of the time-invariant uncertain parameters are assumed to be bounded within given compact sets. An improved condition for the existence of a unique equilibrium point and its global exponential stability of RNNs with known parameters is proposed. Based on this, a sufficient condition for the global robust exponential stability for interval RNNs is obtained. Both of the conditions are expressed in terms of LMIs, which can be checked easily by various recently developed convex optimization algorithms. Examples are provided to demonstrate the reduced conservatism of the proposed exponential stability condition

  10. Principal Curves for Statistical Divergences and an Application to Finance

    Directory of Open Access Journals (Sweden)

    Ana Flávia P. Rodrigues

    2018-05-01

    Full Text Available This paper proposes a method for the beta pricing model under the consideration of non-Gaussian returns by means of a generalization of the mean-variance model and the use of principal curves to define a divergence model for the optimization of the pricing model. We rely on the q-exponential model so consider the properties of the divergences which are used to describe the statistical model and fully characterize the behavior of the assets. We derive the minimum divergence portfolio, which generalizes the Markowitz’s (mean-divergence approach and relying on the information geometrical aspects of the distributions the Capital Asset Pricing Model (CAPM is then derived under the geometrical characterization of the distributions which model the data, all by the consideration of principal curves approach. We discuss the possibility of integration of our model into an adaptive procedure that can be used for the search of optimum points on finance applications.

  11. Sub-exponential mixing of random billiards driven by thermostats

    International Nuclear Information System (INIS)

    Yarmola, Tatiana

    2013-01-01

    We study the class of open continuous-time mechanical particle systems introduced in the paper by Khanin and Yarmola (2013 Commun. Math. Phys. 320 121–47). Using the discrete-time results from Khanin and Yarmola (2013 Commun. Math. Phys. 320 121–47) we demonstrate rigorously that, in continuous time, a unique steady state exists and is sub-exponentially mixing. Moreover, all initial distributions converge to the steady state and, for a large class of initial distributions, convergence to the steady state is sub-exponential. The main obstacle to exponential convergence is the existence of slow particles in the system. (paper)

  12. Exponential Decay Metrics of Topical Tetracaine Hydrochloride Administration Describe Corneal Anesthesia Properties Mechanistically.

    Science.gov (United States)

    Ethington, Jason; Goldmeier, David; Gaynes, Bruce I

    2017-03-01

    To identify pharmacodynamic (PD) and pharmacokinetic (PK) metrics that aid in mechanistic understanding of dosage considerations for prolonged corneal anesthesia. A rabbit model using 0.5% tetracaine hydrochloride was used to induce corneal anesthesia in conjunction with Cochet-Bonnet anesthesiometry. Metrics were derived describing PD-PK parameters of the time-dependent domain of recovery in corneal sensitivity. Curve fitting used a 1-phase exponential dissociation paradigm assuming a 1-compartment PK model. Derivation of metrics including half-life and mean ligand residence time, tau (τ), was predicted by nonlinear regression. Bioavailability was determined by area under the curve of the dose-response relationship with varying drop volumes. Maximal corneal anesthesia maintained a plateau with a recovery inflection at the approximate time of predicted corneal drug half-life. PDs of recovery of corneal anesthesia were consistent with a first-order drug elimination rate. The mean ligand residence time (tau, τ) was 41.7 minutes, and half-life was 28.89 minutes. The mean estimated corneal elimination rate constant (ke) was 0.02402 minute. Duration of corneal anesthesia ranged from 55 to 58 minutes. There was no difference in time domain PD area under the curve between drop volumes. Use of a small drop volume of a topical anesthetic (as low as 11 μL) is bioequivalent to conventional drop size and seems to optimize dosing regiments with a little effect on ke. Prolongation of corneal anesthesia may therefore be best achieved with administration of small drop volumes at time intervals corresponding to the half-life of drug decay from the corneal compartment.

  13. Effect of benzalkonium chloride on viability and energy metabolism in exponential- and stationary-growth-phase cells of Listeria monocytogenes

    NARCIS (Netherlands)

    Luppens, S.B.I.; Abee, T.; Oosterom, J.

    2001-01-01

    The difference in killing exponential- and stationary-phase cells of Listeria monocytogenes by benzalkonium chloride (BAC) was investigated by plate counting and linked to relevant bioenergetic parameters. At a low concentration of BAC (8 mg liter-1), a similar reduction in viable cell numbers was

  14. Age, growth and fecundity of the silver mullet, Mugil curema (Pisces: Mugilidae, in coastal areas of Northeastern Venezuela

    Directory of Open Access Journals (Sweden)

    Baumar J Marin E

    2000-06-01

    Full Text Available We studied the fecundity and growth in populations of the silver mullet, Mugil curema, in coastal areas of northeastern Venezuela between March 1992 and July 1993. The average number of ovocytes in gonads of 23-42 cm adults was 54 x 104, and the relative fecundity was 1311 ovocytes g-1 of fish. The size of mature ovocytes did not vary in different portions of the same gonad (p 0.05 or among the adults in three populations studied. The average egg diameter for adults was 426 µm (CI= 4.34. Age of juveniles, collected from the La Restinga Lagoon at about monthly intervals, from counts of growth lines on the otoliths ranged from 50 to 240 days. The relation of age (number of growth lines to standard length follows an exponential growth curve. The growth of juveniles varied seasonally and was greatest during the rainy season (April to August, when temperatures were highest. The time of spawning has probably been adapted so that peak recruitment into the lagoons occurs just prior to the rainy season when conditions for growth are most favorable.

  15. Population growth and economic growth.

    Science.gov (United States)

    Narayana, D L

    1984-01-01

    This discussion of the issues relating to the problem posed by population explosion in the developing countries and economic growth in the contemporary world covers the following: predictions of economic and social trends; the Malthusian theory of population; the classical or stationary theory of population; the medical triage model; ecological disaster; the Global 2000 study; the limits to growth; critiques of the Limits to Growth model; nonrenewable resources; food and agriculture; population explosion and stabilization; space and ocean colonization; and the limits perspective. The Limits to Growth model, a general equilibrium anti-growth model, is the gloomiest economic model ever constructed. None of the doomsday models, the Malthusian theory, the classical stationary state, the neo-Malthusian medical triage model, the Global 2000 study, are so far reaching in their consequences. The course of events that followed the publication of the "Limits to Growth" in 1972 in the form of 2 oil shocks, food shock, pollution shock, and price shock seemed to bear out formally the gloomy predictions of the thesis with a remarkable speed. The 12 years of economic experience and the knowledge of resource trends postulate that even if the economic pressures visualized by the model are at work they are neither far reaching nor so drastic. Appropriate action can solve them. There are several limitations to the Limits to Growth model. The central theme of the model, which is overshoot and collapse, is unlikely to be the course of events. The model is too aggregative to be realistic. It exaggerates the ecological disaster arising out of the exponential growth of population and industry. The gross underestimation of renewable resources is a basic flaw of the model. The most critical weakness of the model is its gross underestimation of the historical trend of technological progress and the technological possiblities within industry and agriculture. The model does correctly emphasize

  16. Environmental Kuznets Curve for carbon emissions in Pakistan: An empirical investigation

    Energy Technology Data Exchange (ETDEWEB)

    Nasir, Muhammad, E-mail: nasirawan84@yahoo.co [Staff Economist, Pakistan Institute of Development Economics, 44000 Islamabad (Pakistan); Ur Rehman, Faiz, E-mail: faizeconomist@yahoo.co [Department of Economics, Quaid-i-Azam University, Islamabad (Pakistan)

    2011-03-15

    This study investigates the relationship between carbon emissions, income, energy consumption, and foreign trade in Pakistan for the period 1972-2008. By employing the Johansen method of cointegration, the study finds that there is a quadratic long-run relationship between carbon emissions and income, confirming the existence of Environmental Kuznets Curve for Pakistan. Moreover, both energy consumption and foreign trade are found to have positive effects on emissions. The short-run results have, however, denied the existence of the Environmental Kuznets Curve. The short-run results are unique to the existing literature in the sense that none of the long-run determinants of emissions is significant. The contradictory results of short- and long-run give policy makers the opportunity to formulate different types of growth policies for the two terms taking environmental issues into consideration. In addition, the uni-directional causality from growth to energy consumption suggests that the policy makers should not only focus on forecasting future demand for energy with different growth scenarios but also on obtaining the least cost energy. Furthermore, the absence of causality from emissions to growth suggests that Pakistan can curb its carbon emissions without disturbing its economic growth. - Research highlights: {yields} Environmental Kuznets Curve exists only in the long-run in Pakistan. {yields} Both energy consumption and trade openness also affect carbon emissions positively in the long run. {yields} The short-run results have, however, denied the existence of the Environmental Kuznets Curve. {yields} None of the explanatory variables affect emissions in short-run. {yields} There is uni-directional causality from growth to energy consumption. {yields} There is uni-directional causality from growth to emissions.

  17. Environmental Kuznets Curve for carbon emissions in Pakistan: An empirical investigation

    International Nuclear Information System (INIS)

    Nasir, Muhammad; Ur Rehman, Faiz

    2011-01-01

    This study investigates the relationship between carbon emissions, income, energy consumption, and foreign trade in Pakistan for the period 1972-2008. By employing the Johansen method of cointegration, the study finds that there is a quadratic long-run relationship between carbon emissions and income, confirming the existence of Environmental Kuznets Curve for Pakistan. Moreover, both energy consumption and foreign trade are found to have positive effects on emissions. The short-run results have, however, denied the existence of the Environmental Kuznets Curve. The short-run results are unique to the existing literature in the sense that none of the long-run determinants of emissions is significant. The contradictory results of short- and long-run give policy makers the opportunity to formulate different types of growth policies for the two terms taking environmental issues into consideration. In addition, the uni-directional causality from growth to energy consumption suggests that the policy makers should not only focus on forecasting future demand for energy with different growth scenarios but also on obtaining the least cost energy. Furthermore, the absence of causality from emissions to growth suggests that Pakistan can curb its carbon emissions without disturbing its economic growth. - Research highlights: → Environmental Kuznets Curve exists only in the long-run in Pakistan. → Both energy consumption and trade openness also affect carbon emissions positively in the long run. → The short-run results have, however, denied the existence of the Environmental Kuznets Curve. → None of the explanatory variables affect emissions in short-run. → There is uni-directional causality from growth to energy consumption. → There is uni-directional causality from growth to emissions.

  18. A generalized-growth model to characterize the early ascending phase of infectious disease outbreaks

    Directory of Open Access Journals (Sweden)

    Cécile Viboud

    2016-06-01

    Conclusions: Our findings reveal significant variation in epidemic growth patterns across different infectious disease outbreaks and highlights that sub-exponential growth is a common phenomenon, especially for pathogens that are not airborne. Sub-exponential growth profiles may result from heterogeneity in contact structures or risk groups, reactive behavior changes, or the early onset of interventions strategies, and consideration of “deceleration parameters” may be useful to refine existing mathematical transmission models and improve disease forecasts.

  19. An exact formulation of the time-ordered exponential using path-sums

    International Nuclear Information System (INIS)

    Giscard, P.-L.; Lui, K.; Thwaite, S. J.; Jaksch, D.

    2015-01-01

    We present the path-sum formulation for the time-ordered exponential of a time-dependent matrix. The path-sum formulation gives the time-ordered exponential as a branched continued fraction of finite depth and breadth. The terms of the path-sum have an elementary interpretation as self-avoiding walks and self-avoiding polygons on a graph. Our result is based on a representation of the time-ordered exponential as the inverse of an operator, the mapping of this inverse to sums of walks on a graphs, and the algebraic structure of sets of walks. We give examples demonstrating our approach. We establish a super-exponential decay bound for the magnitude of the entries of the time-ordered exponential of sparse matrices. We give explicit results for matrices with commonly encountered sparse structures

  20. An exact formulation of the time-ordered exponential using path-sums

    Science.gov (United States)

    Giscard, P.-L.; Lui, K.; Thwaite, S. J.; Jaksch, D.

    2015-05-01

    We present the path-sum formulation for the time-ordered exponential of a time-dependent matrix. The path-sum formulation gives the time-ordered exponential as a branched continued fraction of finite depth and breadth. The terms of the path-sum have an elementary interpretation as self-avoiding walks and self-avoiding polygons on a graph. Our result is based on a representation of the time-ordered exponential as the inverse of an operator, the mapping of this inverse to sums of walks on a graphs, and the algebraic structure of sets of walks. We give examples demonstrating our approach. We establish a super-exponential decay bound for the magnitude of the entries of the time-ordered exponential of sparse matrices. We give explicit results for matrices with commonly encountered sparse structures.

  1. Comparison of bi-exponential and mono-exponential models of diffusion-weighted imaging for detecting active sacroiliitis in ankylosing spondylitis.

    Science.gov (United States)

    Sun, Haitao; Liu, Kai; Liu, Hao; Ji, Zongfei; Yan, Yan; Jiang, Lindi; Zhou, Jianjun

    2018-04-01

    Background There has been a growing need for a sensitive and effective imaging method for the differentiation of the activity of ankylosing spondylitis (AS). Purpose To compare the performances of intravoxel incoherent motion (IVIM)-derived parameters and the apparent diffusion coefficient (ADC) for distinguishing AS-activity. Material and Methods One hundred patients with AS were divided into active (n = 51) and non-active groups (n = 49) and 21 healthy volunteers were included as control. The ADC, diffusion coefficient ( D), pseudodiffusion coefficient ( D*), and perfusion fraction ( f) were calculated for all groups. Kruskal-Wallis tests and receiver operator characteristic (ROC) curve analysis were performed for all parameters. Results There was good reproducibility of ADC /D and relatively poor reproducibility of D*/f. ADC, D, and f were significantly higher in the active group than in the non-active and control groups (all P  0.050). In the ROC analysis, ADC had the largest AUC for distinguishing between the active group and the non-active group (0.988) and between the active and control groups (0.990). Multivariate logistic regression analysis models showed no diagnostic improvement. Conclusion ADC provided better diagnostic performance than IVIM-derived parameters in differentiating AS activity. Therefore, a straightforward and effective mono-exponential model of diffusion-weighted imaging may be sufficient for differentiating AS activity in the clinic.

  2. Exponential gain of randomness certified by quantum contextuality

    Science.gov (United States)

    Um, Mark; Zhang, Junhua; Wang, Ye; Wang, Pengfei; Kim, Kihwan

    2017-04-01

    We demonstrate the protocol of exponential gain of randomness certified by quantum contextuality in a trapped ion system. The genuine randomness can be produced by quantum principle and certified by quantum inequalities. Recently, randomness expansion protocols based on inequality of Bell-text and Kochen-Specker (KS) theorem, have been demonstrated. These schemes have been theoretically innovated to exponentially expand the randomness and amplify the randomness from weak initial random seed. Here, we report the experimental evidence of such exponential expansion of randomness. In the experiment, we use three states of a 138Ba + ion between a ground state and two quadrupole states. In the 138Ba + ion system, we do not have detection loophole and we apply a methods to rule out certain hidden variable models that obey a kind of extended noncontextuality.

  3. Exponential growth and selection in self-replicating materials from DNA origami rafts

    Science.gov (United States)

    He, Xiaojin; Sha, Ruojie; Zhuo, Rebecca; Mi, Yongli; Chaikin, Paul M.; Seeman, Nadrian C.

    2017-10-01

    Self-replication and evolution under selective pressure are inherent phenomena in life, and but few artificial systems exhibit these phenomena. We have designed a system of DNA origami rafts that exponentially replicates a seed pattern, doubling the copies in each diurnal-like cycle of temperature and ultraviolet illumination, producing more than 7 million copies in 24 cycles. We demonstrate environmental selection in growing populations by incorporating pH-sensitive binding in two subpopulations. In one species, pH-sensitive triplex DNA bonds enable parent-daughter templating, while in the second species, triplex binding inhibits the formation of duplex DNA templating. At pH 5.3, the replication rate of species I is ~1.3-1.4 times faster than that of species II. At pH 7.8, the replication rates are reversed. When mixed together in the same vial, the progeny of species I replicate preferentially at pH 7.8 similarly at pH 5.3, the progeny of species II take over the system. This addressable selectivity should be adaptable to the selection and evolution of multi-component self-replicating materials in the nanoscopic-to-microscopic size range.

  4. Quantum Zeno effect for exponentially decaying systems

    International Nuclear Information System (INIS)

    Koshino, Kazuki; Shimizu, Akira

    2004-01-01

    The quantum Zeno effect - suppression of decay by frequent measurements - was believed to occur only when the response of the detector is so quick that the initial tiny deviation from the exponential decay law is detectable. However, we show that it can occur even for exactly exponentially decaying systems, for which this condition is never satisfied, by considering a realistic case where the detector has a finite energy band of detection. The conventional theories correspond to the limit of an infinite bandwidth. This implies that the Zeno effect occurs more widely than expected thus far

  5. Exponential decay activities of radiocesium In mushrooms by the help of acetic acid

    International Nuclear Information System (INIS)

    Kunova, V.; Dvorak, P.; Benova, K.

    2004-01-01

    Gross activity of radiocesium in food from environmental ecosystems is decreasing slower than it was supposed and therefore it is subject for public repeatedly. Belong there mushrooms, game and wood fruits. Interest in this problems is and substantial improvement tighten up admissible levels of radioactive contamination of food ( 137 Cs and 134 Cs) for irradiation after Chernobyl in public notice for Czech republic is 600 Bq/kg. It is in unity with European Union. We can search possibilities to decrease content of radiocesium in food. Mainly mushrooms cumulate considerable quantity of radiocesium. Were examined samples Boletus badius of three other condition. Samples come from two other localities. Activity of radiocesium was detected by gamma-spectrometry (f.Canberra). For decrease content of radiocesium was using elution in 2% solution of acetate acid. Curve of graphic analysis have exponential nature. (authors)

  6. An integral parametrization of the bacterial growth curve experimental demonstration with E. coli C{sub 6}00 bacteria; Parametrizacion integrada de la curva de crecimiento bacteriano. Comprobacion experimental para E. coli C{sub 6}00

    Energy Technology Data Exchange (ETDEWEB)

    Garces, F; Vidania, R de

    1984-07-01

    In this work an integral parametrization of the bacterial growth curve is presented. The values of the parameters are obtained by fitting to the experimental data. Those parameters, with allow to describe the growth in its different phases, are the followings: slopes of the curve in its three parts and the time which divides the last two phases of the bacterial growth. The experimental data are bacterial densities measured by optical methods. The bacteria used was the E. coli C{sub 6}00. (Author)

  7. Exponential smoothing weighted correlations

    Science.gov (United States)

    Pozzi, F.; Di Matteo, T.; Aste, T.

    2012-06-01

    In many practical applications, correlation matrices might be affected by the "curse of dimensionality" and by an excessive sensitiveness to outliers and remote observations. These shortcomings can cause problems of statistical robustness especially accentuated when a system of dynamic correlations over a running window is concerned. These drawbacks can be partially mitigated by assigning a structure of weights to observational events. In this paper, we discuss Pearson's ρ and Kendall's τ correlation matrices, weighted with an exponential smoothing, computed on moving windows using a data-set of daily returns for 300 NYSE highly capitalized companies in the period between 2001 and 2003. Criteria for jointly determining optimal weights together with the optimal length of the running window are proposed. We find that the exponential smoothing can provide more robust and reliable dynamic measures and we discuss that a careful choice of the parameters can reduce the autocorrelation of dynamic correlations whilst keeping significance and robustness of the measure. Weighted correlations are found to be smoother and recovering faster from market turbulence than their unweighted counterparts, helping also to discriminate more effectively genuine from spurious correlations.

  8. Universality of accelerating change

    Science.gov (United States)

    Eliazar, Iddo; Shlesinger, Michael F.

    2018-03-01

    On large time scales the progress of human technology follows an exponential growth trend that is termed accelerating change. The exponential growth trend is commonly considered to be the amalgamated effect of consecutive technology revolutions - where the progress carried in by each technology revolution follows an S-curve, and where the aging of each technology revolution drives humanity to push for the next technology revolution. Thus, as a collective, mankind is the 'intelligent designer' of accelerating change. In this paper we establish that the exponential growth trend - and only this trend - emerges universally, on large time scales, from systems that combine together two elements: randomness and amalgamation. Hence, the universal generation of accelerating change can be attained by systems with no 'intelligent designer'.

  9. Evaluation of glass leaching as nutrient source for microalgae growth; Evaluacion del comportamiento de vidrios lixiviados como nutrientes de algas

    Energy Technology Data Exchange (ETDEWEB)

    Grabska, N.; Tamayo, A.; Mazo, M. A.; Pascual, L.; Rubio, J.

    2015-10-01

    Three glasses with an elemental composition similar to the nutrient ratio required for Spirulina platensis growth and with different SiO{sub 2} content have been prepared. The glasses were crushed and sieved into 2 different fractions and the effect of the particle size has been studied in terms of the leaching kinetics of each element. The chemical analysis of the leaching water was used for obtaining the dissolution rate curves for each element taking part of the glass composition. From the calculation of the leaching rate constant and the exponential constant of the lixiviation reaction, it has been evaluated the Spirulina platensis growth in ambient normal conditions of light, temperature and pH of the growing media. It has been concluded that, either from the modification of the chemical composition of the glass or its particle size, it is possible to tune the delivery of the nutrients to match the growth rate of Spirulina platensis. (Author)

  10. Mutant number distribution in an exponentially growing population

    Science.gov (United States)

    Keller, Peter; Antal, Tibor

    2015-01-01

    We present an explicit solution to a classic model of cell-population growth introduced by Luria and Delbrück (1943 Genetics 28 491-511) 70 years ago to study the emergence of mutations in bacterial populations. In this model a wild-type population is assumed to grow exponentially in a deterministic fashion. Proportional to the wild-type population size, mutants arrive randomly and initiate new sub-populations of mutants that grow stochastically according to a supercritical birth and death process. We give an exact expression for the generating function of the total number of mutants at a given wild-type population size. We present a simple expression for the probability of finding no mutants, and a recursion formula for the probability of finding a given number of mutants. In the ‘large population-small mutation’ limit we recover recent results of Kessler and Levine (2014 J. Stat. Phys. doi:10.1007/s10955-014-1143-3) for a fully stochastic version of the process.

  11. Residual, restarting and Richardson iteration for the matrix exponential

    NARCIS (Netherlands)

    Bochev, Mikhail A.; Grimm, Volker; Hochbruck, Marlis

    2013-01-01

    A well-known problem in computing some matrix functions iteratively is the lack of a clear, commonly accepted residual notion. An important matrix function for which this is the case is the matrix exponential. Suppose the matrix exponential of a given matrix times a given vector has to be computed.

  12. Residual, restarting and Richardson iteration for the matrix exponential

    NARCIS (Netherlands)

    Bochev, Mikhail A.

    2010-01-01

    A well-known problem in computing some matrix functions iteratively is a lack of a clear, commonly accepted residual notion. An important matrix function for which this is the case is the matrix exponential. Assume, the matrix exponential of a given matrix times a given vector has to be computed. We

  13. Exponential B-splines and the partition of unity property

    DEFF Research Database (Denmark)

    Christensen, Ole; Massopust, Peter

    2012-01-01

    We provide an explicit formula for a large class of exponential B-splines. Also, we characterize the cases where the integer-translates of an exponential B-spline form a partition of unity up to a multiplicative constant. As an application of this result we construct explicitly given pairs of dual...

  14. Brief Report: Examining children’s disruptive behavior in the wake of trauma - A two-piece growth curve model before and after a school shooting

    Science.gov (United States)

    Liao, Yue; Shonkoff, Eleanor T.; Barnett, Elizabeth; Wen, CK Fred; Miller, Kimberly A.; Eddy, J. Mark

    2015-01-01

    School shootings may have serious negative impacts on children years after the event. Previous research suggests that children exposed to traumatic events experience heightened fear, anxiety, and feelings of vulnerability, but little research has examined potential aggressive and disruptive behavioral reactions. Utilizing a longitudinal dataset in which a local school shooting occurred during the course of data collection, this study sought to investigate whether the trajectory of disruptive behaviors was affected by the shooting. A two-piece growth curve model was used to examine the trajectory of disruptive behaviors during the pre-shooting years (i.e., piece one) and post-shooting years (i.e., piece two). Results indicated that the two-piece growth curve model fit the data better than the one-piece model and that the school shooting precipitated a faster decline in aggressive behaviors. This study demonstrated a novel approach to examining effects of an unexpected traumatic event on behavioral trajectories using an existing longitudinal data set. PMID:26298676

  15. Growth curves and age-related changes in carcass characteristics, organs, serum parameters, and intestinal transporter gene expression in domestic pigeon (Columba livia).

    Science.gov (United States)

    Gao, C Q; Yang, J X; Chen, M X; Yan, H C; Wang, X Q

    2016-04-01

    Two experiments were conducted to fit growth curves, and determine age-related changes in carcass characteristics, organs, serum biochemical parameters, and gene expression of intestinal nutrient transporters in domestic pigeon (Columba livia). In experiment 1, body weight (BW) of 30 pigeons was respectively determined at 1, 3, 7, 14, 21, 28, and 35 days old to fit growth curves and to describe the growth of pigeons. In experiment 2, eighty-four 1-day-old squabs were grouped by weight into 7 groups. On d 1, 3, 7, 14, 21, 28, and 35, twelve birds from each group were randomly selected for slaughter and post-slaughter analysis. The results showed that BW of pigeons increased rapidly from d 1 to d 28 (a 25.7-fold increase), and then had little change until d 35. The Logistic, Gompertz, and Von Bertalanffy functions can all be well fitted with the growth curve of domestic pigeons (R2>0.90) and the Gompertz model showed the highest R2value among the models (R2=0.9997). The equation of Gompertz model was Y=507.72×e-(3.76exp(-0.17t))(Y=BW of pigeon (g); t=time (day)). In addition, breast meat yield (%) increased with age throughout the experiment, whereas the leg meat yield (%) reached to the peak on d 14. Serum total protein, albumin, globulin, and glucose concentration were increased with age, whereas serum uric acid concentration was decreased (P<0.05). Furthermore, the gene expressions of nutrient transporters (y+LAT2, LAT1, B0AT1, PepT1, and NHE2) in jejunum of pigeon were increased with age. The results of correlation analysis showed the gene expressions of B0AT1, PepT1, and NHE2 had positive correlations with BW (0.73

  16. Trend in BMI z-score among Private Schools’ Students in Delhi using Multiple Imputation for Growth Curve Model

    Directory of Open Access Journals (Sweden)

    Vinay K Gupta

    2016-06-01

    Full Text Available Objective: The aim of the study is to assess the trend in mean BMI z-score among private schools’ students from their anthropometric records when there were missing values in the outcome. Methodology: The anthropometric measurements of student from class 1 to 12 were taken from the records of two private schools in Delhi, India from 2005 to 2010. These records comprise of an unbalanced longitudinal data that is not all the students had measurements recorded at each year. The trend in mean BMI z-score was estimated through growth curve model. Prior to that, missing values of BMI z-score were imputed through multiple imputation using the same model. A complete case analysis was also performed after excluding missing values to compare the results with those obtained from analysis of multiply imputed data. Results: The mean BMI z-score among school student significantly decreased over time in imputed data (β= -0.2030, se=0.0889, p=0.0232 after adjusting age, gender, class and school. Complete case analysis also shows a decrease in mean BMI z-score though it was not statistically significant (β= -0.2861, se=0.0987, p=0.065. Conclusions: The estimates obtained from multiple imputation analysis were better than those of complete data after excluding missing values in terms of lower standard errors. We showed that anthropometric measurements from schools records can be used to monitor the weight status of children and adolescents and multiple imputation using growth curve model can be useful while analyzing such data

  17. Waveform inversion with exponential damping using a deconvolution-based objective function

    KAUST Repository

    Choi, Yun Seok

    2016-09-06

    The lack of low frequency components in seismic data usually leads full waveform inversion into the local minima of its objective function. An exponential damping of the data, on the other hand, generates artificial low frequencies, which can be used to admit long wavelength updates for waveform inversion. Another feature of exponential damping is that the energy of each trace also exponentially decreases with source-receiver offset, where the leastsquare misfit function does not work well. Thus, we propose a deconvolution-based objective function for waveform inversion with an exponential damping. Since the deconvolution filter includes a division process, it can properly address the unbalanced energy levels of the individual traces of the damped wavefield. Numerical examples demonstrate that our proposed FWI based on the deconvolution filter can generate a convergent long wavelength structure from the artificial low frequency components coming from an exponential damping.

  18. Flower Power: Sunflowers as a Model for Logistic Growth

    Science.gov (United States)

    Fernandez, Eileen; Geist, Kristi A.

    2011-01-01

    Logistic growth displays an interesting pattern: It starts fast, exhibiting the rapid growth characteristic of exponential models. As time passes, it slows in response to constraints such as limited resources or reallocation of energy. The growth continues to slow until it reaches a limit, called capacity. When the growth describes a population,…

  19. The Matrix exponential, Dynamic Systems and Control

    DEFF Research Database (Denmark)

    Poulsen, Niels Kjølstad

    The matrix exponential can be found in various connections in analysis and control of dynamic systems. In this short note we are going to list a few examples. The matrix exponential usably pops up in connection to the sampling process, whatever it is in a deterministic or a stochastic setting...... or it is a tool for determining a Gramian matrix. This note is intended to be used in connection to the teaching post the course in Stochastic Adaptive Control (02421) given at Informatics and Mathematical Modelling (IMM), The Technical University of Denmark. This work is a result of a study of the litterature....

  20. Non-exponential extinction of radiation by fractional calculus modelling

    International Nuclear Information System (INIS)

    Casasanta, G.; Ciani, D.; Garra, R.

    2012-01-01

    Possible deviations from exponential attenuation of radiation in a random medium have been recently studied in several works. These deviations from the classical Beer-Lambert law were justified from a stochastic point of view by Kostinski (2001) . In his model he introduced the spatial correlation among the random variables, i.e. a space memory. In this note we introduce a different approach, including a memory formalism in the classical Beer-Lambert law through fractional calculus modelling. We find a generalized Beer-Lambert law in which the exponential memoryless extinction is only a special case of non-exponential extinction solutions described by Mittag-Leffler functions. We also justify this result from a stochastic point of view, using the space fractional Poisson process. Moreover, we discuss some concrete advantages of this approach from an experimental point of view, giving an estimate of the deviation from exponential extinction law, varying the optical depth. This is also an interesting model to understand the meaning of fractional derivative as an instrument to transmit randomness of microscopic dynamics to the macroscopic scale.

  1. Brief report: Examining children's disruptive behavior in the wake of trauma - A two-piece growth curve model before and after a school shooting.

    Science.gov (United States)

    Liao, Yue; Shonkoff, Eleanor T; Barnett, Elizabeth; Wen, C K Fred; Miller, Kimberly A; Eddy, J Mark

    2015-10-01

    School shootings may have serious negative impacts on children years after the event. Previous research suggests that children exposed to traumatic events experience heightened fear, anxiety, and feelings of vulnerability, but little research has examined potential aggressive and disruptive behavioral reactions. Utilizing a longitudinal dataset in which a local school shooting occurred during the course of data collection, this study sought to investigate whether the trajectory of disruptive behaviors was affected by the shooting. A two-piece growth curve model was used to examine the trajectory of disruptive behaviors during the pre-shooting years (i.e., piece one) and post-shooting years (i.e., piece two). Results indicated that the two-piece growth curve model fit the data better than the one-piece model and that the school shooting precipitated a faster decline in aggressive behaviors. This study demonstrated a novel approach to examining effects of an unexpected traumatic event on behavioral trajectories using an existing longitudinal data set. Copyright © 2015 The Foundation for Professionals in Services for Adolescents. Published by Elsevier Ltd. All rights reserved.

  2. Study of thermal conductivity and thermal rectification in exponential mass graded lattices

    Energy Technology Data Exchange (ETDEWEB)

    Shah, Tejal N. [Bhavan' s Sheth R.A. College of Science, Khanpur, Ahmedabad 380 001, Gujarat (India); Gajjar, P.N., E-mail: pngajjar@rediffmail.com [Department of Physics, University School of Sciences, Gujarat University, Ahmedabad 380 009, Gujarat (India)

    2012-01-09

    Concept of exponential mass variation of oscillators along the chain length of N oscillators is proposed in the present Letter. The temperature profile and thermal conductivity of one-dimensional (1D) exponential mass graded harmonic and anharmonic lattices are studied on the basis of Fermi–Pasta–Ulam (FPU) β model. Present findings conclude that the exponential mass graded chain provide higher conductivity than that of linear mass graded chain. The exponential mass graded anharmonic chain generates the thermal rectification of 70–75% which is better than linear mass graded materials, so far. Thus instead of using linear mass graded material, the use of exponential mass graded material will be a better and genuine choice for controlling the heat flow at nano-scale. -- Highlights: ► In PRE 82 (2010) 040101, use of mass graded material as a thermal devices is explored. ► Concept of exponential mass graded material is proposed. ► The rectification obtained is about 70–75% which is better than linear mass graded materials. ► The exponential mass graded material will be a better choice for the thermal devices at nano-scale.

  3. Exponential Correlation of IQ and the Wealth of Nations

    Science.gov (United States)

    Dickerson, Richard E.

    2006-01-01

    Plots of mean IQ and per capita real Gross Domestic Product for groups of 81 and 185 nations, as collected by Lynn and Vanhanen, are best fitted by an exponential function of the form: GDP = "a" * 10["b"*(IQ)], where "a" and "b" are empirical constants. Exponential fitting yields markedly higher correlation coefficients than either linear or…

  4. New Results of Global Exponential Stabilization for BLDCMs System

    OpenAIRE

    Fengxia Tian; Fangchao Zhen; Guopeng Zhou; Xiaoxin Liao

    2015-01-01

    The global exponential stabilization for brushless direct current motor (BLDCM) system is studied. Four linear and simple feedback controllers are proposed to realize the global stabilization of BLDCM with exponential convergence rate; the control law used in each theorem is less conservative and more concise. Finally, an example is given to demonstrate the correctness of the proposed results.

  5. A note on exponential convergence of neural networks with unbounded distributed delays

    Energy Technology Data Exchange (ETDEWEB)

    Chu Tianguang [Intelligent Control Laboratory, Center for Systems and Control, Department of Mechanics and Engineering Science, Peking University, Beijing 100871 (China)]. E-mail: chutg@pku.edu.cn; Yang Haifeng [Intelligent Control Laboratory, Center for Systems and Control, Department of Mechanics and Engineering Science, Peking University, Beijing 100871 (China)

    2007-12-15

    This note examines issues concerning global exponential convergence of neural networks with unbounded distributed delays. Sufficient conditions are derived by exploiting exponentially fading memory property of delay kernel functions. The method is based on comparison principle of delay differential equations and does not need the construction of any Lyapunov functionals. It is simple yet effective in deriving less conservative exponential convergence conditions and more detailed componentwise decay estimates. The results of this note and [Chu T. An exponential convergence estimate for analog neural networks with delay. Phys Lett A 2001;283:113-8] suggest a class of neural networks whose globally exponentially convergent dynamics is completely insensitive to a wide range of time delays from arbitrary bounded discrete type to certain unbounded distributed type. This is of practical interest in designing fast and reliable neural circuits. Finally, an open question is raised on the nature of delay kernels for attaining exponential convergence in an unbounded distributed delayed neural network.

  6. A note on exponential convergence of neural networks with unbounded distributed delays

    International Nuclear Information System (INIS)

    Chu Tianguang; Yang Haifeng

    2007-01-01

    This note examines issues concerning global exponential convergence of neural networks with unbounded distributed delays. Sufficient conditions are derived by exploiting exponentially fading memory property of delay kernel functions. The method is based on comparison principle of delay differential equations and does not need the construction of any Lyapunov functionals. It is simple yet effective in deriving less conservative exponential convergence conditions and more detailed componentwise decay estimates. The results of this note and [Chu T. An exponential convergence estimate for analog neural networks with delay. Phys Lett A 2001;283:113-8] suggest a class of neural networks whose globally exponentially convergent dynamics is completely insensitive to a wide range of time delays from arbitrary bounded discrete type to certain unbounded distributed type. This is of practical interest in designing fast and reliable neural circuits. Finally, an open question is raised on the nature of delay kernels for attaining exponential convergence in an unbounded distributed delayed neural network

  7. Growth and mortality of larval Myctophum affine (Myctophidae, Teleostei).

    Science.gov (United States)

    Namiki, C; Katsuragawa, M; Zani-Teixeira, M L

    2015-04-01

    The growth and mortality rates of Myctophum affine larvae were analysed based on samples collected during the austral summer and winter of 2002 from south-eastern Brazilian waters. The larvae ranged in size from 2·75 to 14·00 mm standard length (L(S)). Daily increment counts from 82 sagittal otoliths showed that the age of M. affine ranged from 2 to 28 days. Three models were applied to estimate the growth rate: linear regression, exponential model and Laird-Gompertz model. The exponential model best fitted the data, and L(0) values from exponential and Laird-Gompertz models were close to the smallest larva reported in the literature (c. 2·5 mm L(S)). The average growth rate (0·33 mm day(-1)) was intermediate among lanternfishes. The mortality rate (12%) during the larval period was below average compared with other marine fish species but similar to some epipelagic fishes that occur in the area. © 2015 The Fisheries Society of the British Isles.

  8. Crack problem in superconducting cylinder with exponential distribution of critical-current density

    Science.gov (United States)

    Zhao, Yufeng; Xu, Chi; Shi, Liang

    2018-04-01

    The general problem of a center crack in a long cylindrical superconductor with inhomogeneous critical-current distribution is studied based on the extended Bean model for zero-field cooling (ZFC) and field cooling (FC) magnetization processes, in which the inhomogeneous parameter η is introduced for characterizing the critical-current density distribution in inhomogeneous superconductor. The effect of the inhomogeneous parameter η on both the magnetic field distribution and the variations of the normalized stress intensity factors is also obtained based on the plane strain approach and J-integral theory. The numerical results indicate that the exponential distribution of critical-current density will lead a larger trapped field inside the inhomogeneous superconductor and cause the center of the cylinder to fracture more easily. In addition, it is worth pointing out that the nonlinear field distribution is unique to the Bean model by comparing the curve shapes of the magnetization loop with homogeneous and inhomogeneous critical-current distribution.

  9. Effect of algal growth phase on Aureococcus anophagefferens susceptibility to hydrogen peroxide

    Energy Technology Data Exchange (ETDEWEB)

    Randhawa, Varunpreet; Thakkar, Megha; Wei, Liping, E-mail: liping.wei@njit.edu

    2013-10-15

    Highlights: •Brown tide alga's susceptibility to H{sub 2}O{sub 2} was examined via growth and physiology responses. •The study was designed equalizing the influence of the media and cell density in test cultures. •Stationary cells was more sensitive to H{sub 2}O{sub 2} than exponential cells. •Stationary cells showed weaker non-protein thiol up-regulation than exponential cells. •Stationary cells mediated greater H{sub 2}O{sub 2} decomposition than exponential cells did. -- Abstract: A cell's growth phase could affect its susceptibility to a biocide in microbial control. This study examines the growth phase dependent susceptibility of a brown tide bloom alga Aureococcus anophagefferens to microbial biocide hydrogen peroxide (H{sub 2}O{sub 2}). Test cultures of A. anophagefferens cells in exponential and stationary growth phase and similar initial cell density (1.6 × 10{sup 6} cells mL{sup −1}) were exposed to 0.4–1.6 mg L{sup −1} H{sub 2}O{sub 2}. Changes in algal growth (in vivo fluorescence, total chlorophyll a, and cell density), cell physiology (maximum quantum yield of photosystem II, and total intracellular non-protein thiols), and H{sub 2}O{sub 2} decomposition were quantified. Results show that the stationary phase cells are more susceptible to H{sub 2}O{sub 2} than the exponential phase cells, and this is attributed to the weaker ROS (reactive oxygen species) scavenging system and consequently greater cell damage in stationary phase cells. The stationary phase cells potentially require 30–40% less H{sub 2}O{sub 2} to reach 90% removal within 12 h of treatment as compared to the exponential phase cells. The results have practical implications in brown tide bloom control with respect to the timing and the dosage of H{sub 2}O{sub 2} application.

  10. Peak oil analyzed with a logistic function and idealized Hubbert curve

    International Nuclear Information System (INIS)

    Gallagher, Brian

    2011-01-01

    A logistic function is used to characterize peak and ultimate production of global crude oil and petroleum-derived liquid fuels. Annual oil production data were incrementally summed to construct a logistic curve in its initial phase. Using a curve-fitting approach, a population-growth logistic function was applied to complete the cumulative production curve. The simulated curve was then deconstructed into a set of annual oil production data producing an 'idealized' Hubbert curve. An idealized Hubbert curve (IHC) is defined as having properties of production data resulting from a constant growth-rate under fixed resource limits. An IHC represents a potential production curve constructed from cumulative production data and provides a new perspective for estimating peak production periods and remaining resources. The IHC model data show that idealized peak oil production occurred in 2009 at 83.2 Mb/d (30.4 Gb/y). IHC simulations of truncated historical oil production data produced similar results and indicate that this methodology can be useful as a prediction tool. - Research Highlights: →Global oil production data were analyzed by a simple curve fitting method. →Best fit-curve results were obtained using two logistic functions on select data. →A broad potential oil production peak is forecast for the years from 2004 to 2014. →Similar results were obtained using historical data from about 10 to 30 years ago. →Two potential oil production decline scenarios were presented and compared.

  11. Relationship between Industrial Water Use and Economic Growth in China: Insights from an Environmental Kuznets Curve

    Directory of Open Access Journals (Sweden)

    Alun Gu

    2017-07-01

    Full Text Available Global inequity and the unbalance of water resources has been a critical issue for many years; and the Chinese per capita water resources are only 1/4 of the global average. Meanwhile, as the Chinese economy is growing rapidly, the demand of Chinese industrial water use is also increasing. In this case, it is important to balance the relationship between economic growth and industrial water use. In this study, a reduction model is established for the northeastern, northern coastal, eastern coastal, southern coastal, middle Yellow River, middle Yangtze River, southwestern, and northwestern regions to verify the environmental Kuznets curve (EKC for their respective industrial water use and provide theoretical support for decision making from an economic perspective. It adopts the per capita industrial water use and GDP of the eight economic zones from 2002 to 2014. The unit root test and co-integration test were adopted to analyze the stationarity of the data, and the triple reduction model was used for the fitting of variables. The relationship between per capita industrial water use and GDP showed an inverted U-shaped curve from 2002 to 2014 for China, as well as for the eastern coastal and middle Yangtze River regions, with the coordinates of the turning points being (9.8749, 4.6735, (10.3098, 5.4783, and (9.8184, 5.0622, respectively. The per capita GDP at the turning point of the inverted U-shaped curve is 18,000–30,000 Yuan (at constant prices from 2000. This study provides important thoughts and lessons for collaborative research into the relationship between industrial water consumption and economic development. The central government should focus on the central and western regions when creating policies for water resource management and technological development to improve their industrial water use efficiency.

  12. Environmental Kuznets Curve Hypothesis: A Perspective of Sustainable Development in Indonesia

    Directory of Open Access Journals (Sweden)

    Galuh Nuansa Citrasmara

    2018-01-01

    Full Text Available Sustainable development with three main pillars, namely environmental, economic, and social, is the concept of country’s development to achieve inclusive economic growth, good environmental quality, and improvement of people's welfare. However, the dominance of economic factors cause various environmental problem. This phenomenon occurs in most of developing countries, including in Indonesia. The relationship between economic activity and environmental quality has been widely discussed and empirically tested by scholars. This descriptive research analysed the hypothesis called Environmental Kuznets Curve (EKC from a perspective of sustainable development in Indonesia. EKC hypothesis illustrates the relationship between economic growth and environmental degradation forming an inverted U-curve, indicating that at the beginning of development, environmental quality will decrease along with increasing economic growth, and then reached a certain point the environmental quality will gradually improve. In this paper will be discussed how the relationship between environmental quality and economic growth in Indonesia was investigated. The preliminary results show that most of the empirical studies use the conventional approach, in which the CO2 emission used as the proxy of environmental degradation. The existence of inverted U-curve is also inconclusive. Therefore, the extension research on the relationship between economic growth and environmental quality in Indonesia using the EKC hypothesis is required.

  13. Environmental Kuznets Curve Hypothesis: A Perspective of Sustainable Development in Indonesia

    Science.gov (United States)

    Nuansa, Citrasmara Galuh; Widodo, Wahyu

    2018-02-01

    Sustainable development with three main pillars, namely environmental, economic, and social, is the concept of country's development to achieve inclusive economic growth, good environmental quality, and improvement of people's welfare. However, the dominance of economic factors cause various environmental problem. This phenomenon occurs in most of developing countries, including in Indonesia. The relationship between economic activity and environmental quality has been widely discussed and empirically tested by scholars. This descriptive research analysed the hypothesis called Environmental Kuznets Curve (EKC) from a perspective of sustainable development in Indonesia. EKC hypothesis illustrates the relationship between economic growth and environmental degradation forming an inverted U-curve, indicating that at the beginning of development, environmental quality will decrease along with increasing economic growth, and then reached a certain point the environmental quality will gradually improve. In this paper will be discussed how the relationship between environmental quality and economic growth in Indonesia was investigated. The preliminary results show that most of the empirical studies use the conventional approach, in which the CO2 emission used as the proxy of environmental degradation. The existence of inverted U-curve is also inconclusive. Therefore, the extension research on the relationship between economic growth and environmental quality in Indonesia using the EKC hypothesis is required.

  14. Asymptotic estimates and exponential stability for higher-order monotone difference equations

    Directory of Open Access Journals (Sweden)

    Pituk Mihály

    2005-01-01

    Full Text Available Asymptotic estimates are established for higher-order scalar difference equations and inequalities the right-hand sides of which generate a monotone system with respect to the discrete exponential ordering. It is shown that in some cases the exponential estimates can be replaced with a more precise limit relation. As corollaries, a generalization of discrete Halanay-type inequalities and explicit sufficient conditions for the global exponential stability of the zero solution are given.

  15. Asymptotic estimates and exponential stability for higher-order monotone difference equations

    Directory of Open Access Journals (Sweden)

    Mihály Pituk

    2005-03-01

    Full Text Available Asymptotic estimates are established for higher-order scalar difference equations and inequalities the right-hand sides of which generate a monotone system with respect to the discrete exponential ordering. It is shown that in some cases the exponential estimates can be replaced with a more precise limit relation. As corollaries, a generalization of discrete Halanay-type inequalities and explicit sufficient conditions for the global exponential stability of the zero solution are given.

  16. Theoretical and Experimental Study of Bacterial Colony Growth in 3D

    Science.gov (United States)

    Shao, Xinxian; Mugler, Andrew; Nemenman, Ilya

    2014-03-01

    Bacterial cells growing in liquid culture have been well studied and modeled. However, in nature, bacteria often grow as biofilms or colonies in physically structured habitats. A comprehensive model for population growth in such conditions has not yet been developed. Based on the well-established theory for bacterial growth in liquid culture, we develop a model for colony growth in 3D in which a homogeneous colony of cells locally consume a diffusing nutrient. We predict that colony growth is initially exponential, as in liquid culture, but quickly slows to sub-exponential after nutrient is locally depleted. This prediction is consistent with our experiments performed with E. coli in soft agar. Our model provides a baseline to which studies of complex growth process, such as such as spatially and phenotypically heterogeneous colonies, must be compared.

  17. Analytic results for asymmetric random walk with exponential transition probabilities

    International Nuclear Information System (INIS)

    Gutkowicz-Krusin, D.; Procaccia, I.; Ross, J.

    1978-01-01

    We present here exact analytic results for a random walk on a one-dimensional lattice with asymmetric, exponentially distributed jump probabilities. We derive the generating functions of such a walk for a perfect lattice and for a lattice with absorbing boundaries. We obtain solutions for some interesting moment properties, such as mean first passage time, drift velocity, dispersion, and branching ratio for absorption. The symmetric exponential walk is solved as a special case. The scaling of the mean first passage time with the size of the system for the exponentially distributed walk is determined by the symmetry and is independent of the range

  18. Exponential Sensitivity and its Cost in Quantum Physics.

    Science.gov (United States)

    Gilyén, András; Kiss, Tamás; Jex, Igor

    2016-02-10

    State selective protocols, like entanglement purification, lead to an essentially non-linear quantum evolution, unusual in naturally occurring quantum processes. Sensitivity to initial states in quantum systems, stemming from such non-linear dynamics, is a promising perspective for applications. Here we demonstrate that chaotic behaviour is a rather generic feature in state selective protocols: exponential sensitivity can exist for all initial states in an experimentally realisable optical scheme. Moreover, any complex rational polynomial map, including the example of the Mandelbrot set, can be directly realised. In state selective protocols, one needs an ensemble of initial states, the size of which decreases with each iteration. We prove that exponential sensitivity to initial states in any quantum system has to be related to downsizing the initial ensemble also exponentially. Our results show that magnifying initial differences of quantum states (a Schrödinger microscope) is possible; however, there is a strict bound on the number of copies needed.

  19. Dynamics of curved fronts

    CERN Document Server

    Pelce, Pierre

    1989-01-01

    In recent years, much progress has been made in the understanding of interface dynamics of various systems: hydrodynamics, crystal growth, chemical reactions, and combustion. Dynamics of Curved Fronts is an important contribution to this field and will be an indispensable reference work for researchers and graduate students in physics, applied mathematics, and chemical engineering. The book consist of a 100 page introduction by the editor and 33 seminal articles from various disciplines.

  20. Global impulsive exponential synchronization of stochastic perturbed chaotic delayed neural networks

    International Nuclear Information System (INIS)

    Hua-Guang, Zhang; Tie-Dong, Ma; Jie, Fu; Shao-Cheng, Tong

    2009-01-01

    In this paper, the global impulsive exponential synchronization problem of a class of chaotic delayed neural networks (DNNs) with stochastic perturbation is studied. Based on the Lyapunov stability theory, stochastic analysis approach and an efficient impulsive delay differential inequality, some new exponential synchronization criteria expressed in the form of the linear matrix inequality (LMI) are derived. The designed impulsive controller not only can globally exponentially stabilize the error dynamics in mean square, but also can control the exponential synchronization rate. Furthermore, to estimate the stable region of the synchronization error dynamics, a novel optimization control algorithm is proposed, which can deal with the minimum problem with two nonlinear terms coexisting in LMIs effectively. Simulation results finally demonstrate the effectiveness of the proposed method

  1. Intravoxel water diffusion heterogeneity MR imaging of nasopharyngeal carcinoma using stretched exponential diffusion model

    International Nuclear Information System (INIS)

    Lai, Vincent; Khong, Pek Lan; Lee, Victor Ho Fun; Lam, Ka On; Sze, Henry Chun Kin; Chan, Queenie

    2015-01-01

    To determine the utility of stretched exponential diffusion model in characterisation of the water diffusion heterogeneity in different tumour stages of nasopharyngeal carcinoma (NPC). Fifty patients with newly diagnosed NPC were prospectively recruited. Diffusion-weighted MR imaging was performed using five b values (0-2,500 s/mm 2 ). Respective stretched exponential parameters (DDC, distributed diffusion coefficient; and alpha (α), water heterogeneity) were calculated. Patients were stratified into low and high tumour stage groups based on the American Joint Committee on Cancer (AJCC) staging for determination of the predictive powers of DDC and α using t test and ROC curve analyses. The mean ± standard deviation values were DDC = 0.692 ± 0.199 (x 10 -3 mm 2 /s) for low stage group vs 0.794 ± 0.253 (x 10 -3 mm 2 /s) for high stage group; α = 0.792 ± 0.145 for low stage group vs 0.698 ± 0.155 for high stage group. α was significantly lower in the high stage group while DDC was negatively correlated. DDC and α were both reliable independent predictors (p < 0.001), with α being more powerful. Optimal cut-off values were (sensitivity, specificity, positive likelihood ratio, negative likelihood ratio) DDC = 0.692 x 10 -3 mm 2 /s (94.4 %, 64.3 %, 2.64, 0.09), α = 0.720 (72.2 %, 100 %, -, 0.28). The heterogeneity index α is robust and can potentially help in staging and grading prediction in NPC. (orig.)

  2. Partial drying accelerates bacterial growth recovery to rewetting

    DEFF Research Database (Denmark)

    Meisner, Annelein; Leizeaga, Ainara; Rousk, Johannes

    2017-01-01

    , bacterial growth rates increase immediately in a linear fashion. In the Type 2 pattern, bacterial growth rates increase exponentially after a lag period. However, soils are often only partially dried. Partial drying (higher remaining moisture content before rewetting) may be considered a less harsh...

  3. On Extended Exponential General Linear Methods PSQ with S>Q ...

    African Journals Online (AJOL)

    This paper is concerned with the construction and Numerical Analysis of Extended Exponential General Linear Methods. These methods, in contrast to other methods in literatures, consider methods with the step greater than the stage order (S>Q).Numerical experiments in this study, indicate that Extended Exponential ...

  4. Inference for exponentiated general class of distributions based on record values

    Directory of Open Access Journals (Sweden)

    Samah N. Sindi

    2017-09-01

    Full Text Available The main objective of this paper is to suggest and study a new exponentiated general class (EGC of distributions. Maximum likelihood, Bayesian and empirical Bayesian estimators of the parameter of the EGC of distributions based on lower record values are obtained. Furthermore, Bayesian prediction of future records is considered. Based on lower record values, the exponentiated Weibull distribution, its special cases of distributions and exponentiated Gompertz distribution are applied to the EGC of distributions.  

  5. Exploring parameter constraints on quintessential dark energy: The exponential model

    International Nuclear Information System (INIS)

    Bozek, Brandon; Abrahamse, Augusta; Albrecht, Andreas; Barnard, Michael

    2008-01-01

    We present an analysis of a scalar field model of dark energy with an exponential potential using the Dark Energy Task Force (DETF) simulated data models. Using Markov Chain Monte Carlo sampling techniques we examine the ability of each simulated data set to constrain the parameter space of the exponential potential for data sets based on a cosmological constant and a specific exponential scalar field model. We compare our results with the constraining power calculated by the DETF using their 'w 0 -w a ' parametrization of the dark energy. We find that respective increases in constraining power from one stage to the next produced by our analysis give results consistent with DETF results. To further investigate the potential impact of future experiments, we also generate simulated data for an exponential model background cosmology which cannot be distinguished from a cosmological constant at DETF 'Stage 2', and show that for this cosmology good DETF Stage 4 data would exclude a cosmological constant by better than 3σ

  6. Possible stretched exponential parametrization for humidity absorption in polymers.

    Science.gov (United States)

    Hacinliyan, A; Skarlatos, Y; Sahin, G; Atak, K; Aybar, O O

    2009-04-01

    Polymer thin films have irregular transient current characteristics under constant voltage. In hydrophilic and hydrophobic polymers, the irregularity is also known to depend on the humidity absorbed by the polymer sample. Different stretched exponential models are studied and it is shown that the absorption of humidity as a function of time can be adequately modelled by a class of these stretched exponential absorption models.

  7. The behaviour of effective coupling constants in 'finite' grand unification theories in curved spacetime

    International Nuclear Information System (INIS)

    Buchbinder, I.L.; Odintsov, S.D.; Lichtzier, I.M.

    1989-01-01

    The question of the behaviour of effective coupling constants in one-loop 'finite' grand unification theories in curved spacetime is investigated. It is shown that in strong gravitational fields the effective coupling constant, corresponding to the parameter of non-minimal interaction of scalar and gravitational fields, tends to the conformal value or increases in an exponential fashion. The one-loop effective potential is obtained with accuracy to linear curvature terms. It is shown that, in external supergravity, supersymmetric finite theories admit asymptotic conformal invariance. (Author)

  8. Rimonabant reduces the essential value of food in the genetically obese Zucker rat: an exponential demand analysis.

    Science.gov (United States)

    Rasmussen, Erin B; Reilly, William; Buckley, Jessica; Boomhower, Steven R

    2012-02-01

    Research on free-food intake suggests that cannabinoids are implicated in the regulation of feeding. Few studies, however, have characterized how environmental factors that affect food procurement interact with cannabinoid drugs that reduce food intake. Demand analysis provides a framework to understand how cannabinoid blockers, such as rimonabant, interact with effort in reducing demand for food. The present study examined the effects rimonabant had on demand for sucrose in obese Zucker rats when effort to obtain food varied and characterized the data using the exponential ("essential value") model of demand. Twenty-nine male (15 lean, 14 obese) Zucker rats lever-pressed under eight fixed ratio (FR) schedules of sucrose reinforcement, in which the number of lever-presses to gain access to a single sucrose pellet varied between 1 and 300. After behavior stabilized under each FR schedule, acute doses of rimonabant (1-10mg/kg) were administered prior to some sessions. The number of food reinforcers and responses in each condition was averaged and the exponential and linear demand equations were fit to the data. These demand equations quantify the value of a reinforcer by its sensitivity to price (FR) increases. Under vehicle conditions, obese Zucker rats consumed more sucrose pellets than leans at smaller fixed ratios; however, they were equally sensitive to price increases with both models of demand. Rimonabant dose-dependently reduced reinforcers and responses for lean and obese rats across all FR schedules. Data from the exponential analysis suggest that rimonabant dose-dependently increased elasticity, i.e., reduced the essential value of sucrose, a finding that is consistent with graphical depictions of normalized demand curves. Copyright © 2011 Elsevier Inc. All rights reserved.

  9. Long memory in time series of economic growth and convergence

    NARCIS (Netherlands)

    Silverberg, G.; Verspagen, B.

    1999-01-01

    One of the most hotly debated topics in macroeconomics in recent years has been the nature of fluctuations in the growth process of aggregate output in the longer term. Traditionally, economists have conceived of the growth process as consisting of a deterministic trend (such as exponential growth)

  10. A random matrix model for elliptic curve L-functions of finite conductor

    International Nuclear Information System (INIS)

    Dueñez, E; Huynh, D K; Keating, J P; Snaith, N C; Miller, S J

    2012-01-01

    We propose a random-matrix model for families of elliptic curve L-functions of finite conductor. A repulsion of the critical zeros of these L-functions away from the centre of the critical strip was observed numerically by Miller (2006 Exp. Math. 15 257–79); such behaviour deviates qualitatively from the conjectural limiting distribution of the zeros (for large conductors this distribution is expected to approach the one-level density of eigenvalues of orthogonal matrices after appropriate rescaling). Our purpose here is to provide a random-matrix model for Miller’s surprising discovery. We consider the family of even quadratic twists of a given elliptic curve. The main ingredient in our model is a calculation of the eigenvalue distribution of random orthogonal matrices whose characteristic polynomials are larger than some given value at the symmetry point in the spectra. We call this sub-ensemble of SO(2N) the excised orthogonal ensemble. The sieving-off of matrices with small values of the characteristic polynomial is akin to the discretization of the central values of L-functions implied by the formulae of Waldspurger and Kohnen–Zagier. The cut-off scale appropriate to modelling elliptic curve L-functions is exponentially small relative to the matrix size N. The one-level density of the excised ensemble can be expressed in terms of that of the well-known Jacobi ensemble, enabling the former to be explicitly calculated. It exhibits an exponentially small (on the scale of the mean spacing) hard gap determined by the cut-off value, followed by soft repulsion on a much larger scale. Neither of these features is present in the one-level density of SO(2N). When N → ∞ we recover the limiting orthogonal behaviour. Our results agree qualitatively with Miller’s discrepancy. Choosing the cut-off appropriately gives a model in good quantitative agreement with the number-theoretical data. (paper)

  11. Mechanistic formulation of a lineal-quadratic-linear (LQL) model: Split-dose experiments and exponentially decaying sources

    International Nuclear Information System (INIS)

    Guerrero, Mariana; Carlone, Marco

    2010-01-01

    Purpose: In recent years, several models were proposed that modify the standard linear-quadratic (LQ) model to make the predicted survival curve linear at high doses. Most of these models are purely phenomenological and can only be applied in the particular case of acute doses per fraction. The authors consider a mechanistic formulation of a linear-quadratic-linear (LQL) model in the case of split-dose experiments and exponentially decaying sources. This model provides a comprehensive description of radiation response for arbitrary dose rate and fractionation with only one additional parameter. Methods: The authors use a compartmental formulation of the LQL model from the literature. They analytically solve the model's differential equations for the case of a split-dose experiment and for an exponentially decaying source. They compare the solutions of the survival fraction with the standard LQ equations and with the lethal-potentially lethal (LPL) model. Results: In the case of the split-dose experiment, the LQL model predicts a recovery ratio as a function of dose per fraction that deviates from the square law of the standard LQ. The survival fraction as a function of time between fractions follows a similar exponential law as the LQ but adds a multiplicative factor to the LQ parameter β. The LQL solution for the split-dose experiment is very close to the LPL prediction. For the decaying source, the differences between the LQL and the LQ solutions are negligible when the half-life of the source is much larger than the characteristic repair time, which is the clinically relevant case. Conclusions: The compartmental formulation of the LQL model can be used for arbitrary dose rates and provides a comprehensive description of dose response. When the survival fraction for acute doses is linear for high dose, a deviation of the square law formula of the recovery ratio for split doses is also predicted.

  12. Global exponential stability for discrete-time neural networks with variable delays

    International Nuclear Information System (INIS)

    Chen Wuhua; Lu Xiaomei; Liang Dongying

    2006-01-01

    This Letter provides new exponential stability criteria for discrete-time neural networks with variable delays. The main technique is to reduce exponential convergence estimation of the neural network solution to that of one component of the corresponding solution by constructing Lyapunov function based on M-matrix. By introducing the tuning parameter diagonal matrix, the delay-independent and delay-dependent exponential stability conditions have been unified in the same mathematical formula. The effectiveness of the new results are illustrated by three examples

  13. New results for exponential synchronization of linearly coupled ordinary differential systems

    International Nuclear Information System (INIS)

    Tong Ping; Chen Shi-Hua

    2017-01-01

    This paper investigates the exponential synchronization of linearly coupled ordinary differential systems. The intrinsic nonlinear dynamics may not satisfy the QUAD condition or weak-QUAD condition. First, it gives a new method to analyze the exponential synchronization of the systems. Second, two theorems and their corollaries are proposed for the local or global exponential synchronization of the coupled systems. Finally, an application to the linearly coupled Hopfield neural networks and several simulations are provided for verifying the effectiveness of the theoretical results. (paper)

  14. Exponential decay and exponential recovery of modal gains in high count rate channel electron multipliers

    International Nuclear Information System (INIS)

    Hahn, S.F.; Burch, J.L.

    1980-01-01

    A series of data on high count rate channel electron multipliers revealed an initial drop and subsequent recovery of gains in exponential fashion. The FWHM of the pulse height distribution at the initial stage of testing can be used as a good criterion for the selection of operating bias voltage of the channel electron multiplier

  15. The exponential critical state of high-Tc ceramics

    International Nuclear Information System (INIS)

    Castro, H.; Rinderer, L.

    1994-01-01

    The critical current in high-Tc materials is strongly reduced by a magnetic field. We studied this dependency for tubular YBCO samples. We find an exponential drop as the field is increased from zero up to some tens of oersted. This behavior was already observed by others, however little work has been done in this direction. We define what we call the ''exponential critical state'' of HTSC and compare the prediction for the magnetization with experimental data. Furthermore, the ''Kim critical state'' is obtained as the small field limit. (orig.)

  16. Testable Implications of Quasi-Hyperbolic and Exponential Time Discounting

    OpenAIRE

    Echenique, Federico; Imai, Taisuke; Saito, Kota

    2014-01-01

    We present the first revealed-preference characterizations of the models of exponential time discounting, quasi-hyperbolic time discounting, and other time-separable models of consumers’ intertemporal decisions. The characterizations provide non-parametric revealed-preference tests, which we take to data using the results of a recent experiment conducted by Andreoni and Sprenger (2012). For such data, we find that less than half the subjects are consistent with exponential discounting, and on...

  17. Development of hot and cool executive functions in middle childhood: Three-year growth curves of decision making and working memory updating.

    Science.gov (United States)

    Lensing, Nele; Elsner, Birgit

    2018-05-07

    Although middle childhood is an important period for the development of hot and cool executive functions (EFs), longitudinal studies investigating trajectories of childhood EF development are still limited and little is known about predictors for individual developmental trajectories. The current study examined the development of two typical facets of cool and hot EFs over a 3-year period during middle childhood, comparing a younger cohort (6- and 7-year-olds at the first wave [T1]; n = 621) and an older cohort (8- and 9-year-olds at T1; n = 975) of children. "Cool" working memory updating (WM) was assessed using a backward digit span task, and "hot" decision making (DM) was assessed using a child variant of the Iowa Gambling Task. Linear latent growth curve analyses revealed evidence for developmental growth as well as interindividual variance in the initial level and rate of change in both EF facets. Initial level of WM was positively associated with age (both between and within cohorts), socioeconomic status, verbal ability, and processing speed, whereas initial levels of DM were, in addition to a (potentially age-related) cohort effect, exclusively predicted by gender, with boys outperforming girls. None of the variables predicted the rate of change, that is, the developmental trajectories. However, younger children, as compared with older children, had slightly steeper WM growth curves over time, hinting at a leveling off in the development of WM during middle childhood. In sum, these data add important evidence to the understanding of hot and cool EF development during middle childhood. Copyright © 2018 Elsevier Inc. All rights reserved.

  18. Mutant number distribution in an exponentially growing population

    International Nuclear Information System (INIS)

    Keller, Peter; Antal, Tibor

    2015-01-01

    We present an explicit solution to a classic model of cell-population growth introduced by Luria and Delbrück (1943 Genetics 28 491–511) 70 years ago to study the emergence of mutations in bacterial populations. In this model a wild-type population is assumed to grow exponentially in a deterministic fashion. Proportional to the wild-type population size, mutants arrive randomly and initiate new sub-populations of mutants that grow stochastically according to a supercritical birth and death process. We give an exact expression for the generating function of the total number of mutants at a given wild-type population size. We present a simple expression for the probability of finding no mutants, and a recursion formula for the probability of finding a given number of mutants. In the ‘large population-small mutation’ limit we recover recent results of Kessler and Levine (2014 J. Stat. Phys. doi:10.1007/s10955-014-1143-3) for a fully stochastic version of the process. (paper)

  19. Master curve characterization of the fracture toughness behavior in SA508 Gr.4N low alloy steels

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Ki-Hyoung, E-mail: shirimp@kaist.ac.k [Department of Materials Science and Engineering, KAIST, Daejeon 305-701 (Korea, Republic of); Kim, Min-Chul; Lee, Bong-Sang [Nuclear Materials Research Division, KAERI, Daejeon 305-353 (Korea, Republic of); Wee, Dang-Moon [Department of Materials Science and Engineering, KAIST, Daejeon 305-701 (Korea, Republic of)

    2010-08-15

    The fracture toughness properties of the tempered martensitic SA508 Gr.4N Ni-Mo-Cr low alloy steel for reactor pressure vessels were investigated by using the master curve concept. These results were compared to those of the bainitic SA508 Gr.3 Mn-Mo-Ni low alloy steel, which is a commercial RPV material. The fracture toughness tests were conducted by 3-point bending with pre-cracked charpy (PCVN) specimens according to the ASTM E1921-09c standard method. The temperature dependency of the fracture toughness was steeper than those predicted by the standard master curve, while the bainitic SA508 Gr.3 steel fitted well with the standard prediction. In order to properly evaluate the fracture toughness of the Gr.4N steels, the exponential coefficient of the master curve equation was changed and the modified curve was applied to the fracture toughness test results of model alloys that have various chemical compositions. It was found that the modified curve provided a better description for the overall fracture toughness behavior and adequate T{sub 0} determination for the tempered martensitic SA508 Gr.4N steels.

  20. Exponential stability of switched linear systems with time-varying delay

    Directory of Open Access Journals (Sweden)

    Satiracoo Pairote

    2007-11-01

    Full Text Available We use a Lyapunov-Krasovskii functional approach to establish the exponential stability of linear systems with time-varying delay. Our delay-dependent condition allows to compute simultaneously the two bounds that characterize the exponential stability rate of the solution. A simple procedure for constructing switching rule is also presented.

  1. Stretched versus compressed exponential kinetics in α-helix folding

    International Nuclear Information System (INIS)

    Hamm, Peter; Helbing, Jan; Bredenbeck, Jens

    2006-01-01

    In a recent paper (J. Bredenbeck, J. Helbing, J.R. Kumita, G.A. Woolley, P. Hamm, α-helix formation in a photoswitchable peptide tracked from picoseconds to microseconds by time resolved IR spectroscopy, Proc. Natl. Acad. Sci USA 102 (2005) 2379), we have investigated the folding of a photo-switchable α-helix with a kinetics that could be fit by a stretched exponential function exp(-(t/τ) β ). The stretching factor β became smaller as the temperature was lowered, a result which has been interpreted in terms of activated diffusion on a rugged energy surface. In the present paper, we discuss under which conditions diffusion problems occur with stretched exponential kinetics (β 1). We show that diffusion problems do have a strong tendency to yield stretched exponential kinetics, yet, that there are conditions (strong perturbation from equilibrium, performing the experiment in the folding direction) under which compressed exponential kinetics would be expected instead. We discuss the kinetics on free energy surfaces predicted by simple initiation-propagation models (zipper models) of α-helix folding, as well as by folding funnel models. We show that our recent experiment has been performed under condition for which models with strong downhill driving force, such as the zipper model, would predict compressed, rather than stretched exponential kinetics, in disagreement with the experimental observation. We therefore propose that the free energy surface along a reaction coordinate that governs the folding kinetics must be relatively flat and has a shape similar to a 1D golf course. We discuss how this conclusion can be unified with the thermodynamically well established zipper model by introducing an additional kinetic reaction coordinate

  2. Design of a 9-loop quasi-exponential waveform generator.

    Science.gov (United States)

    Banerjee, Partha; Shukla, Rohit; Shyam, Anurag

    2015-12-01

    We know in an under-damped L-C-R series circuit, current follows a damped sinusoidal waveform. But if a number of sinusoidal waveforms of decreasing time period, generated in an L-C-R circuit, be combined in first quarter cycle of time period, then a quasi-exponential nature of output current waveform can be achieved. In an L-C-R series circuit, quasi-exponential current waveform shows a rising current derivative and thereby finds many applications in pulsed power. Here, we have described design and experiment details of a 9-loop quasi-exponential waveform generator. In that, design details of magnetic switches have also been described. In the experiment, output current of 26 kA has been achieved. It has been shown that how well the experimentally obtained output current profile matches with the numerically computed output.

  3. Proximity hybridization-mediated isothermal exponential amplification for ultrasensitive electrochemical protein detection

    Directory of Open Access Journals (Sweden)

    Yu Y

    2017-08-01

    Full Text Available Yanyan Yu, Gaoxing Su, Hongyan Zhu, Qing Zhu, Yong Chen, Bohui Xu, Yuqin Li, Wei Zhang School of Pharmacy, Nantong University, Nantong, People’s Republic of China Abstract: In this study, we fabricated a novel electrochemical biosensing platform on the basis of target-triggered proximity hybridization-mediated isothermal exponential amplification reaction (EXPAR for ultrasensitive protein analysis. Through rational design, the aptamers for protein recognition were integrated within two DNA probes. Via proximity hybridization principle, the affinity protein-binding event was converted into DNA assembly process. The recognition of protein by aptamers can trigger the strand displacement through the increase of the local concentrations of the involved probes. As a consequence, the output DNA was displaced, which can hybridize with the duplex probes immobilized on the electrode surface subsequently, leading to the initiation of the EXPAR as well as the cleavage of duplex probes. Each cleavage will release the gold nanoparticles (AuNPs binding sequence. With the modification of G-quadruplex sequence, electrochemical signals were yielded by the AuNPs through oxidizing 3,3',5,5'-tetramethylbenzidine in the presence of H2O2. The study we proposed exhibited high sensitivity toward platelet-derived growth factor BB (PDGF-BB with the detection limit of 52 fM. And, this method also showed great selectivity among the PDGF isoforms and performed well in spiked human serum samples. Keywords: electrochemical biosensor, proximity hybridization, PDGF-BB, isothermal exponential amplification, G-quadruplex 

  4. Exponential Potential versus Dark Matter

    Science.gov (United States)

    1993-10-15

    scale of the solar system. Galaxy, Dark matter , Galaxy cluster, Gravitation, Quantum gravity...A two parameter exponential potential explains the anomalous kinematics of galaxies and galaxy clusters without need for the myriad ad hoc dark ... matter models currently in vogue. It also explains much about the scales and structures of galaxies and galaxy clusters while being quite negligible on the

  5. Demonstration of the exponential decay law using beer froth

    International Nuclear Information System (INIS)

    Leike, A.

    2002-01-01

    The volume of beer froth decays exponentially with time. This property is used to demonstrate the exponential decay law in the classroom. The decay constant depends on the type of beer and can be used to differentiate between different beers. The analysis shows in a transparent way the techniques of data analysis commonly used in science - consistency checks of theoretical models with the data, parameter estimation and determination of confidence intervals. (author)

  6. THE ATKINSON INDEX, THE MORAN STATISTIC, AND TESTING EXPONENTIALITY

    OpenAIRE

    Nao, Mimoto; Ricardas, Zitikis; Department of Statistics and Probability, Michigan State University; Department of Statistical and Actuarial Sciences, University of Western Ontario

    2008-01-01

    Constructing tests for exponentiality has been an active and fruitful research area, with numerous applications in engineering, biology and other sciences concerned with life-time data. In the present paper, we construct and investigate powerful tests for exponentiality based on two well known quantities: the Atkinson index and the Moran statistic. We provide an extensive study of the performance of the tests and compare them with those already available in the literature.

  7. [Responses of Picea likiangensis radial growth to climate change in the Small Zhongdian area of Yunnan Province, Southwest China].

    Science.gov (United States)

    Zhao, Zhi-Jiang; Tan, Liu-Yi; Kang, Dong-Wei; Liu, Qi-Jing; Li, Jun-Qing

    2012-03-01

    Picea likiangensis (Franch. ) Pritz. primary forest is one of the dominant forest types in the Small Zhongdian area in Shangri-La County of Yunnan Province. In this paper, the responses of P. likiangensis tree-ring width to climate change were analyzed by dendrochronological methods, and the dendrochronology was built by using relatively conservative detrending negative exponential curves or linear regression. Correlation analysis and response function analysis were applied to explore the relationships between the residual chronology series (RES) and climatic factors at different time scales, and pointer year analysis was used to explain the reasons of producing narrow and wide rings. In the study area, the radial growth of P. likiangensis and the increasing air temperature from 1990 to 2008 had definite 'abruption'. The temperature and precipitation in previous year growth season were the main factors limiting the present year radial growth, and especially, the temperature in previous July played a negative feedback role in the radial growth, while the sufficient precipitation in previous July promoted the radial growth. The differences in the temperature variation and precipitation variation in previous year were the main reasons for the formation of narrow and wide rings. P. likiangensis radial growth was not sensitive to the variation of PDSI.

  8. Modelling the interactions between Pseudomonas putida and Escherichia coli O157:H7 in fish-burgers: use of the lag-exponential model and of a combined interaction index.

    Science.gov (United States)

    Speranza, B; Bevilacqua, A; Mastromatteo, M; Sinigaglia, M; Corbo, M R

    2010-08-01

    The objective of the current study was to examine the interactions between Pseudomonas putida and Escherichia coli O157:H7 in coculture studies on fish-burgers packed in air and under different modified atmospheres (30 : 40 : 30 O(2) : CO(2) : N(2), 5 : 95 O(2) : CO(2) and 50 : 50 O(2) : CO(2)), throughout the storage at 8 degrees C. The lag-exponential model was applied to describe the microbial growth. To give a quantitative measure of the occurring microbial interactions, two simple parameters were developed: the combined interaction index (CII) and the partial interaction index (PII). Under air, the interaction was significant (P exponential growth phase (CII, 1.72), whereas under the modified atmospheres, the interactions were highly significant (P exponential and in the stationary phase (CII ranged from 0.33 to 1.18). PII values for E. coli O157:H7 were lower than those calculated for Ps. putida. The interactions occurring into the system affected both E. coli O157:H7 and pseudomonads subpopulations. The packaging atmosphere resulted in a key element. The article provides some useful information on the interactions occurring between E. coli O157:H7 and Ps. putida on fish-burgers. The proposed index describes successfully the competitive growth of both micro-organisms, giving also a quantitative measure of a qualitative phenomenon.

  9. Flare Characteristics from X-ray Light Curves

    Science.gov (United States)

    Gryciuk, M.; Siarkowski, M.; Sylwester, J.; Gburek, S.; Podgorski, P.; Kepa, A.; Sylwester, B.; Mrozek, T.

    2017-06-01

    A new methodology is given to determine basic parameters of flares from their X-ray light curves. Algorithms are developed from the analysis of small X-ray flares occurring during the deep solar minimum of 2009, between Solar Cycles 23 and 24, observed by the Polish Solar Photometer in X-rays (SphinX) on the Complex Orbital Observations Near-Earth of Activity of the Sun-Photon (CORONAS- Photon) spacecraft. One is a semi-automatic flare detection procedure that gives start, peak, and end times for single ("elementary") flare events under the assumption that the light curve is a simple convolution of a Gaussian and exponential decay functions. More complex flares with multiple peaks can generally be described by a sum of such elementary flares. Flare time profiles in the two energy ranges of SphinX (1.16 - 1.51 keV, 1.51 - 15 keV) are used to derive temperature and emission measure as a function of time during each flare. The result is a comprehensive catalogue - the SphinX Flare Catalogue - which contains 1600 flares or flare-like events and is made available for general use. The methods described here can be applied to observations made by Geosynchronous Operational Environmental Satellites (GOES), the Reuven Ramaty High Energy Solar Spectroscopic Imager (RHESSI) and other broad-band spectrometers.

  10. Recent developments in exponential random graph (p*) models for social networks

    NARCIS (Netherlands)

    Robins, Garry; Snijders, Tom; Wang, Peng; Handcock, Mark; Pattison, Philippa

    This article reviews new specifications for exponential random graph models proposed by Snijders et al. [Snijders, T.A.B., Pattison, P., Robins, G.L., Handcock, M., 2006. New specifications for exponential random graph models. Sociological Methodology] and demonstrates their improvement over

  11. Global exponential stability for nonautonomous cellular neural networks with delays

    International Nuclear Information System (INIS)

    Zhang Qiang; Wei Xiaopeng; Xu Jin

    2006-01-01

    In this Letter, by utilizing Lyapunov functional method and Halanay inequalities, we analyze global exponential stability of nonautonomous cellular neural networks with delay. Several new sufficient conditions ensuring global exponential stability of the network are obtained. The results given here extend and improve the earlier publications. An example is given to demonstrate the effectiveness of the obtained results

  12. Hierarchical Bayesian analysis to incorporate age uncertainty in growth curve analysis and estimates of age from length: Florida manatee (Trichechus manatus) carcasses

    Science.gov (United States)

    Schwarz, L.K.; Runge, M.C.

    2009-01-01

    Age estimation of individuals is often an integral part of species management research, and a number of ageestimation techniques are commonly employed. Often, the error in these techniques is not quantified or accounted for in other analyses, particularly in growth curve models used to describe physiological responses to environment and human impacts. Also, noninvasive, quick, and inexpensive methods to estimate age are needed. This research aims to provide two Bayesian methods to (i) incorporate age uncertainty into an age-length Schnute growth model and (ii) produce a method from the growth model to estimate age from length. The methods are then employed for Florida manatee (Trichechus manatus) carcasses. After quantifying the uncertainty in the aging technique (counts of ear bone growth layers), we fit age-length data to the Schnute growth model separately by sex and season. Independent prior information about population age structure and the results of the Schnute model are then combined to estimate age from length. Results describing the age-length relationship agree with our understanding of manatee biology. The new methods allow us to estimate age, with quantified uncertainty, for 98% of collected carcasses: 36% from ear bones, 62% from length.

  13. Parent Prevention Communication Profiles and Adolescent Substance Use: A Latent Profile Analysis and Growth Curve Model

    Science.gov (United States)

    Choi, Hye Jeong; Miller-Day, Michelle; Shin, YoungJu; Hecht, Michael L.; Pettigrew, Jonathan; Krieger, Janice L.; Lee, JeongKyu; Graham, John W.

    2017-01-01

    This current study identifies distinct parent prevention communication profiles and examines whether youth with different parental communication profiles have varying substance use trajectories over time. Eleven schools in two rural school districts in the Midwestern United States were selected, and 784 students were surveyed at three time points from the beginning of 7th grade to the end of 8th grade. A series of latent profile analyses were performed to identify discrete profiles/subgroups of substance-specific prevention communication (SSPC). The results revealed a 4-profile model of SSPC: Active-Open, Passive-Open, Active-Silent, and Passive-Silent. A growth curve model revealed different rates of lifetime substance use depending on the youth’s SSPC profile. These findings have implications for parenting interventions and tailoring messages for parents to fit specific SSPC profiles. PMID:29056872

  14. ON THE R-CURVE BEHAVIOR OF HUMAN TOOTH ENAMEL

    OpenAIRE

    Bajaj, Devendra; Arola, Dwayne

    2009-01-01

    In this study the crack growth resistance behavior and fracture toughness of human tooth enamel were quantified using incremental crack growth measures and conventional fracture mechanics. Results showed that enamel undergoes an increase in crack growth resistance (i.e. rising R-curve) with crack extension from the outer to the inner enamel, and that the rise in toughness is function of distance from the Dentin Enamel Junction (DEJ). The outer enamel exhibited the lowest apparent toughness (0...

  15. Coupling of online control and inhibitory systems in children with atypical motor development: A growth curve modelling study.

    Science.gov (United States)

    Ruddock, Scott; Caeyenberghs, Karen; Piek, Jan; Sugden, David; Hyde, Christian; Morris, Sue; Rigoli, Daniela; Steenbergen, Bert; Wilson, Peter

    2016-11-01

    Previous research indicates that children with Developmental Coordination Disorder (DCD) show deficits performing online corrections, an issue exacerbated by adding inhibitory constraints; however, cross-sectional data suggests that these deficits may reduce with age. Using a longitudinal design, the aim of the study presented here was to model the coupling that occurs between inhibitory systems and (predictive) online control in typically developing children (TDC) and in those with Developmental Coordination Disorder (DCD) over an extended period of time, using a framework of interactive specialization. We predicted that TDC would show a non-linear growth pattern, consistent with re-organisation in the coupling during the middle childhood period, while DCD would display a developmental lag. A group of 196 children (111 girls and 85 boys) aged between 6 and 12years participated in the study. Children were classified as DCD according to research criteria. Using a cohort sequential design, both TDC and DCD groups were divided into age cohorts. Predictive (online) control was defined operationally by performance on a Double-Jump Reaching Task (DJRT), which was assessed at 6-month intervals over two years (5 time points in total). Inhibitory control was examined using an anti-jump condition of the DJRT paradigm whereby children were instructed to touch a target location in the hemispace opposite a cued location. For the TDC group, model comparison using growth curve analysis revealed that a quadratic trend was the most appropriate fit with evidence of rapid improvement in anti-reach performance up until middle childhood (around 8-9years of age), followed by a more gradual rate of improvement into late childhood and early adolescence. This pattern was evident on both chronometric and kinematic measures. In contrast, for children with DCD, a linear function provided the best to fit on the key metrics, with a slower rate of improvement than controls. We conclude that

  16. An exponential observer for the generalized Rossler chaotic system

    International Nuclear Information System (INIS)

    Sun, Y.-J.

    2009-01-01

    In this paper, the generalized Rossler chaotic system is considered and the state observation problem of such a system is investigated. Based on the time-domain approach, a state observer for the generalized Rossler chaotic system is developed to guarantee the global exponential stability of the resulting error system. Moreover, the guaranteed exponential convergence rate can be arbitrarily pre-specified. Finally, a numerical example is provided to illustrate the feasibility and effectiveness of the obtained result.

  17. Necessary and Sufficient Condition for Local Exponential Synchronization of Nonlinear Systems

    NARCIS (Netherlands)

    Andrieu, Vincent; Jayawardhana, Bayu; Tarbouriech, Sophie

    2015-01-01

    Based on recent works on transverse exponential stability, some necessary and sufficient conditions for the existence of a (locally) exponential synchronizer are established. We show that the existence of a structured synchronizer is equivalent to the existence of a stabilizer for the individual

  18. The evolution of stellar exponential discs

    NARCIS (Netherlands)

    Ferguson, AMN; Clarke, CJ

    2001-01-01

    Models of disc galaxies which invoke viscosity-driven radial flows have long been known to provide a natural explanation for the origin of stellar exponential discs, under the assumption that the star formation and viscous time-scales are comparable. We present models which invoke simultaneous star

  19. Exponential Lower Bounds For Policy Iteration

    OpenAIRE

    Fearnley, John

    2010-01-01

    We study policy iteration for infinite-horizon Markov decision processes. It has recently been shown policy iteration style algorithms have exponential lower bounds in a two player game setting. We extend these lower bounds to Markov decision processes with the total reward and average-reward optimality criteria.

  20. Exponential synchronization of complex networks with nonidentical time-delayed dynamical nodes

    International Nuclear Information System (INIS)

    Cai Shuiming; He Qinbin; Hao Junjun; Liu Zengrong

    2010-01-01

    In this Letter, exponential synchronization of a complex network with nonidentical time-delayed dynamical nodes is considered. Two effective control schemes are proposed to drive the network to synchronize globally exponentially onto any smooth goal dynamics. By applying open-loop control to all nodes and adding some intermittent controllers to partial nodes, some simple criteria for exponential synchronization of such network are established. Meanwhile, a pinning scheme deciding which nodes need to be pinned and a simply approximate formula for estimating the least number of pinned nodes are also provided. By introducing impulsive effects to the open-loop controlled network, another synchronization scheme is developed for the network with nonidentical time-delayed dynamical nodes, and an estimate of the upper bound of impulsive intervals ensuring global exponential stability of the synchronization process is also given. Numerical simulations are presented finally to demonstrate the effectiveness of the theoretical results.

  1. Low mass SN Ia and the late light curve

    International Nuclear Information System (INIS)

    Colgate, S.A.; Fryer, C.L.

    1995-01-01

    The late bolometric light curves of type Ia supernovae, when measured accurately over several years, show an exponential decay with a 56d half-life over a drop in luminosity of 8 magnitudes (10 half-lives). The late-time light curve is thought to be governed by the decay of Co 56 , whose 77d half-life must then be modified to account for the observed decay time. Two mechanisms, both relying upon the positron fraction of the Co 56 decay, have been proposed to explain this modification. One explanation requires a large amount of emission at infra-red wavelengths where it would not be detected. The other explanation has proposed a progressive transparency or leakage of the high energy positrons (Colgate, Petschek and Kriese, 1980). For the positrons to leak out of the expanding nebula at the required rate necessary to produce the modified 56d exponential, the mass of the ejecta from a one foe (10 51 erg in kinetic energy) explosion must be small, M ejec = 0.4M circle-dot with M ejec ∝ KE 0.5 . Thus, in this leakage explanation, any reasonable estimate of the total energy of the explosion requires that the ejected mass be very much less than the Chandrasekhar mass of 1.4M circle-dot . This is very difficult to explain with the ''canonical'' Chandrasekhar-mass thermonuclear explosion that disintegrates the original white dwarf star. This result leads us to pursue alternate mechanisms of type Ia supernovae. These mechanisms include sub-Chandrasekhar thermonuclear explosions and the accretion induced collapse of Chandrasekhar mass white dwarfs. We will summarize the advantages and disadvantages of both mechanisms with considerable detail spent on our new accretion induced collapse simulations. These mechanisms lead to lower Ni 56 production and hence result in type Ia supernovae with luminosities decreased down to ∼ 50% that predicted by the ''standard'' model

  2. Statistical estimation for truncated exponential families

    CERN Document Server

    Akahira, Masafumi

    2017-01-01

    This book presents new findings on nonregular statistical estimation. Unlike other books on this topic, its major emphasis is on helping readers understand the meaning and implications of both regularity and irregularity through a certain family of distributions. In particular, it focuses on a truncated exponential family of distributions with a natural parameter and truncation parameter as a typical nonregular family. This focus includes the (truncated) Pareto distribution, which is widely used in various fields such as finance, physics, hydrology, geology, astronomy, and other disciplines. The family is essential in that it links both regular and nonregular distributions, as it becomes a regular exponential family if the truncation parameter is known. The emphasis is on presenting new results on the maximum likelihood estimation of a natural parameter or truncation parameter if one of them is a nuisance parameter. In order to obtain more information on the truncation, the Bayesian approach is also considere...

  3. Matrix-exponential distributions in applied probability

    CERN Document Server

    Bladt, Mogens

    2017-01-01

    This book contains an in-depth treatment of matrix-exponential (ME) distributions and their sub-class of phase-type (PH) distributions. Loosely speaking, an ME distribution is obtained through replacing the intensity parameter in an exponential distribution by a matrix. The ME distributions can also be identified as the class of non-negative distributions with rational Laplace transforms. If the matrix has the structure of a sub-intensity matrix for a Markov jump process we obtain a PH distribution which allows for nice probabilistic interpretations facilitating the derivation of exact solutions and closed form formulas. The full potential of ME and PH unfolds in their use in stochastic modelling. Several chapters on generic applications, like renewal theory, random walks and regenerative processes, are included together with some specific examples from queueing theory and insurance risk. We emphasize our intention towards applications by including an extensive treatment on statistical methods for PH distribu...

  4. Lagrangian Curves on Spectral Curves of Monopoles

    International Nuclear Information System (INIS)

    Guilfoyle, Brendan; Khalid, Madeeha; Ramon Mari, Jose J.

    2010-01-01

    We study Lagrangian points on smooth holomorphic curves in TP 1 equipped with a natural neutral Kaehler structure, and prove that they must form real curves. By virtue of the identification of TP 1 with the space LE 3 of oriented affine lines in Euclidean 3-space, these Lagrangian curves give rise to ruled surfaces in E 3 , which we prove have zero Gauss curvature. Each ruled surface is shown to be the tangent lines to a curve in E 3 , called the edge of regression of the ruled surface. We give an alternative characterization of these curves as the points in E 3 where the number of oriented lines in the complex curve Σ that pass through the point is less than the degree of Σ. We then apply these results to the spectral curves of certain monopoles and construct the ruled surfaces and edges of regression generated by the Lagrangian curves.

  5. Heterogeneous dipolar theory of the exponential pile

    International Nuclear Information System (INIS)

    Mastrangelo, P.V.

    1981-01-01

    We present a heterogeneous theory of the exponential pile, closely related to NORDHEIM-SCALETTAR's. It is well adapted to lattice whose pitch is relatively large (D-2O, grahpite) and the dimensions of whose channels are not negligible. The anisotropy of neutron diffusion is taken into account by the introduction of dipolar parameters. We express the contribution of each channel to the total flux in the moderator by means of multipolar coefficients. In order to be able to apply conditions of continuity between the flux and their derivatives, on the side of the moderator, we develop in a Fourier series the fluxes found at the periphery of each channel. Using Wronski's relations of Bessel's functions, we express the multipolar coefficients of the surfaces of each channel, on the side of the moderator, by means of the harmonics of each flux and their derivatives. We retain only monopolar (A 0 sub(g)) and dipolar (A 1 sub(g)) coefficients; those of a higher order are ignored. We deduce from these coefficients the systems of homogeneous equations of the exponential pile with monopoles on their own and monopoles plus dipoles. It should be noted that the systems of homogeneous equations of the critical pile are contained in those of the exponential pile. In another article, we develop the calculation of monopolar and dipolar heterogeneous parameters. (orig.)

  6. Exponentiation and deformations of Lie-admissible algebras

    International Nuclear Information System (INIS)

    Myung, H.C.

    1982-01-01

    The exponential function is defined for a finite-dimensional real power-associative algebra with unit element. The application of the exponential function is focused on the power-associative (p,q)-mutation of a real or complex associative algebra. Explicit formulas are computed for the (p,q)-mutation of the real envelope of the spin 1 algebra and the Lie algebra so(3) of the rotation group, in light of earlier investigations of the spin 1/2. A slight variant of the mutated exponential is interpreted as a continuous function of the Lie algebra into some isotope of the corresponding linear Lie group. The second part of this paper is concerned with the representation and deformation of a Lie-admissible algebra. The second cohomology group of a Lie-admissible algebra is introduced as a generalization of those of associative and Lie algebras in the Hochschild and Chevalley-Eilenberg theory. Some elementary theory of algebraic deformation of Lie-admissible algebras is discussed in view of generalization of that of associative and Lie algebras. Lie-admissible deformations are also suggested by the representation of Lie-admissible algebras. Some explicit examples of Lie-admissible deformation are given in terms of the (p,q)-mutation of associative deformation of an associative algebra. Finally, we discuss Lie-admissible deformations of order one

  7. Unwrapped phase inversion with an exponential damping

    KAUST Repository

    Choi, Yun Seok

    2015-07-28

    Full-waveform inversion (FWI) suffers from the phase wrapping (cycle skipping) problem when the frequency of data is not low enough. Unless we obtain a good initial velocity model, the phase wrapping problem in FWI causes a result corresponding to a local minimum, usually far away from the true solution, especially at depth. Thus, we have developed an inversion algorithm based on a space-domain unwrapped phase, and we also used exponential damping to mitigate the nonlinearity associated with the reflections. We construct the 2D phase residual map, which usually contains the wrapping discontinuities, especially if the model is complex and the frequency is high. We then unwrap the phase map and remove these cycle-based jumps. However, if the phase map has several residues, the unwrapping process becomes very complicated. We apply a strong exponential damping to the wavefield to eliminate much of the residues in the phase map, thus making the unwrapping process simple. We finally invert the unwrapped phases using the back-propagation algorithm to calculate the gradient. We progressively reduce the damping factor to obtain a high-resolution image. Numerical examples determined that the unwrapped phase inversion with a strong exponential damping generated convergent long-wavelength updates without low-frequency information. This model can be used as a good starting model for a subsequent inversion with a reduced damping, eventually leading to conventional waveform inversion.

  8. A de-noising algorithm based on wavelet threshold-exponential adaptive window width-fitting for ground electrical source airborne transient electromagnetic signal

    Science.gov (United States)

    Ji, Yanju; Li, Dongsheng; Yu, Mingmei; Wang, Yuan; Wu, Qiong; Lin, Jun

    2016-05-01

    The ground electrical source airborne transient electromagnetic system (GREATEM) on an unmanned aircraft enjoys considerable prospecting depth, lateral resolution and detection efficiency, etc. In recent years it has become an important technical means of rapid resources exploration. However, GREATEM data are extremely vulnerable to stationary white noise and non-stationary electromagnetic noise (sferics noise, aircraft engine noise and other human electromagnetic noises). These noises will cause degradation of the imaging quality for data interpretation. Based on the characteristics of the GREATEM data and major noises, we propose a de-noising algorithm utilizing wavelet threshold method and exponential adaptive window width-fitting. Firstly, the white noise is filtered in the measured data using the wavelet threshold method. Then, the data are segmented using data window whose step length is even logarithmic intervals. The data polluted by electromagnetic noise are identified within each window based on the discriminating principle of energy detection, and the attenuation characteristics of the data slope are extracted. Eventually, an exponential fitting algorithm is adopted to fit the attenuation curve of each window, and the data polluted by non-stationary electromagnetic noise are replaced with their fitting results. Thus the non-stationary electromagnetic noise can be effectively removed. The proposed algorithm is verified by the synthetic and real GREATEM signals. The results show that in GREATEM signal, stationary white noise and non-stationary electromagnetic noise can be effectively filtered using the wavelet threshold-exponential adaptive window width-fitting algorithm, which enhances the imaging quality.

  9. p-Curve and p-Hacking in Observational Research.

    Science.gov (United States)

    Bruns, Stephan B; Ioannidis, John P A

    2016-01-01

    The p-curve, the distribution of statistically significant p-values of published studies, has been used to make inferences on the proportion of true effects and on the presence of p-hacking in the published literature. We analyze the p-curve for observational research in the presence of p-hacking. We show by means of simulations that even with minimal omitted-variable bias (e.g., unaccounted confounding) p-curves based on true effects and p-curves based on null-effects with p-hacking cannot be reliably distinguished. We also demonstrate this problem using as practical example the evaluation of the effect of malaria prevalence on economic growth between 1960 and 1996. These findings call recent studies into question that use the p-curve to infer that most published research findings are based on true effects in the medical literature and in a wide range of disciplines. p-values in observational research may need to be empirically calibrated to be interpretable with respect to the commonly used significance threshold of 0.05. Violations of randomization in experimental studies may also result in situations where the use of p-curves is similarly unreliable.

  10. Globally exponential stability of neural network with constant and variable delays

    International Nuclear Information System (INIS)

    Zhao Weirui; Zhang Huanshui

    2006-01-01

    This Letter presents new sufficient conditions of globally exponential stability of neural networks with delays. We show that these results generalize recently published globally exponential stability results. In particular, several different globally exponential stability conditions in the literatures which were proved using different Lyapunov functionals are generalized and unified by using the same Lyapunov functional and the technique of inequality of integral. A comparison between our results and the previous results admits that our results establish a new set of stability criteria for delayed neural networks. Those conditions are less restrictive than those given in the earlier references

  11. Intravoxel water diffusion heterogeneity MR imaging of nasopharyngeal carcinoma using stretched exponential diffusion model

    Energy Technology Data Exchange (ETDEWEB)

    Lai, Vincent; Khong, Pek Lan [University of Hong Kong, Department of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, Pok Fu Lam (China); Lee, Victor Ho Fun; Lam, Ka On; Sze, Henry Chun Kin [University of Hong Kong, Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, Queen Mary Hospital, Pok Fu Lam (China); Chan, Queenie [Philips Healthcare, Hong Kong, Shatin, New Territories (China)

    2015-06-01

    To determine the utility of stretched exponential diffusion model in characterisation of the water diffusion heterogeneity in different tumour stages of nasopharyngeal carcinoma (NPC). Fifty patients with newly diagnosed NPC were prospectively recruited. Diffusion-weighted MR imaging was performed using five b values (0-2,500 s/mm{sup 2}). Respective stretched exponential parameters (DDC, distributed diffusion coefficient; and alpha (α), water heterogeneity) were calculated. Patients were stratified into low and high tumour stage groups based on the American Joint Committee on Cancer (AJCC) staging for determination of the predictive powers of DDC and α using t test and ROC curve analyses. The mean ± standard deviation values were DDC = 0.692 ± 0.199 (x 10{sup -3} mm{sup 2}/s) for low stage group vs 0.794 ± 0.253 (x 10{sup -3} mm{sup 2}/s) for high stage group; α = 0.792 ± 0.145 for low stage group vs 0.698 ± 0.155 for high stage group. α was significantly lower in the high stage group while DDC was negatively correlated. DDC and α were both reliable independent predictors (p < 0.001), with α being more powerful. Optimal cut-off values were (sensitivity, specificity, positive likelihood ratio, negative likelihood ratio) DDC = 0.692 x 10{sup -3} mm{sup 2}/s (94.4 %, 64.3 %, 2.64, 0.09), α = 0.720 (72.2 %, 100 %, -, 0.28). The heterogeneity index α is robust and can potentially help in staging and grading prediction in NPC. (orig.)

  12. A powerful test for weak periodic signals with unknown light curve shape in sparse data

    International Nuclear Information System (INIS)

    Jager De, O.C.; Raubenheimer, B.C.; Swanepoel, J.W.H.

    1989-01-01

    A problem with most tests for periodicity is that they are powerful enough to detect only certain kinds of periodic shapes in the case of weak signals. This causes a selection effect with the identification of weak periodic signals. A new test for uniformity called the H-test is derived for which the probability distribution is an exponential function. This test is shown to have a very good power against most light curve shapes encountered in X- and γ-ray Astronomy and therefore makes the detection of sources with a larger variety of shapes possible. The use of the H-test is suggested if no a priori information about the light curve shape is available. It is also shown how the probability distribution of the test statistics changes when a periodicity search is conducted using very small steps in the period or frequency range. The flux sensitivity for various light curve shapes is also derived for a few tests and this flux is on average a minimum for the H-test

  13. Global exponential stability of a class of retarded impulsive differential equations with applications

    International Nuclear Information System (INIS)

    Xia Yonghui; Wong, Patricia J.Y.

    2009-01-01

    This paper studies the dynamics of a class of retarded impulsive differential equations (IDE), which generalizes the delayed cellular neural networks (DCNN), delayed bidirectional associative memory (BAM) neural networks and some population growth models. Some sufficient criteria are obtained for the existence and global exponential stability of a unique equilibrium. When the impulsive jumps are absent, our results reduce to its corresponding results for the non-impulsive systems. The approaches are based on Banach's fixed point theorem, matrix theory and its spectral theory. Due to this method, our results generalize and improve many previous known results such as . Some examples are also included to illustrate the feasibility and effectiveness of the results obtained

  14. Nonlinear Growth Models in M"plus" and SAS

    Science.gov (United States)

    Grimm, Kevin J.; Ram, Nilam

    2009-01-01

    Nonlinear growth curves or growth curves that follow a specified nonlinear function in time enable researchers to model complex developmental patterns with parameters that are easily interpretable. In this article we describe how a variety of sigmoid curves can be fit using the M"plus" structural modeling program and the nonlinear…

  15. Stability of the Exponential Functional Equation in Riesz Algebras

    Directory of Open Access Journals (Sweden)

    Bogdan Batko

    2014-01-01

    Full Text Available We deal with the stability of the exponential Cauchy functional equation F(x+y=F(xF(y in the class of functions F:G→L mapping a group (G, + into a Riesz algebra L. The main aim of this paper is to prove that the exponential Cauchy functional equation is stable in the sense of Hyers-Ulam and is not superstable in the sense of Baker. To prove the stability we use the Yosida Spectral Representation Theorem.

  16. Collisional avalanche exponentiation of runaway electrons in electrified plasmas

    International Nuclear Information System (INIS)

    Jayakumar, R.; Fleischmann, H.H.; Zweben, S.J.

    1993-01-01

    In contrast to earlier expectations, it is estimated that generation of runaway electrons from close collisions of existing runaways with cold plasma electrons can be significant even for small electric fields, whenever runaways can gain energies of about 20 MeV or more. In that case, the runaway population will grow exponentially with the energy spectrum showing an exponential decrease towards higher energies. Energy gains of the required magnitude may occur in large tokamak devices as well as in cosmic-ray generation. (orig.)

  17. Non-exponential dynamic relaxation in strongly nonequilibrium nonideal plasmas

    International Nuclear Information System (INIS)

    Morozov, I V; Norman, G E

    2003-01-01

    Relaxation of kinetic energy to the equilibrium state is simulated by the molecular dynamics method for nonideal two-component non-degenerate plasmas. Three limiting examples of initial states of strongly nonequilibrium plasma are considered: zero electron velocities, zero ion velocities and zero velocities of both electrons and ions. The initial non-exponential stage, its duration τ nB and subsequent exponential stages of the relaxation process are studied for a wide range of the nonideality parameter and the ion mass

  18. Growth curve and diet density affect eating motivation, behavior, and body composition of broiler breeders during rearing.

    Science.gov (United States)

    de Los Mozos, J; García-Ruiz, A I; den Hartog, L A; Villamide, M J

    2017-08-01

    The aim of this work has been to assess the effect of diet density [control (CON) or 15% diluted (DIL)] and growth curve [recommended by the genetic line (RBW) or 15% heavier (HBW)] and their interaction on BW uniformity, feeding motivation, behavior, and body composition of broiler breeder pullets. A total of 3,000 one-day-old female breeders Ross 308, distributed in 20 pens, was randomly assigned to each treatment. Feed allowance was weekly adjusted to reach the desired BW. Feed was provided as pelleted (zero to 3 wk) and crumble (4 to 19 wk). Time eating was measured at 7, 11, and 19 weeks. A feeding rate test was performed after 11 weeks. Behavior was observed at 9 and 15 wk, by visual scan. At 6, 13, and 19 wk of age, one bird/pen was slaughtered for weighing different organs and analyzing the composition of empty whole bodies. Treatments did not affect BW uniformity; relative weights of the ovary, oviduct, or gizzard; or protein content of empty BW. Time eating varied with the growth curve at 19 wk (P motivation. Behavior was affected by the age and by the time of the d measured, but it did not change with the treatments. Birds spent most time pecking objects (50%), feeding (28%), and drinking (17%). Pullets fed DIL had 8% lower breast yield at different ages and higher empty digestive tracts at 6 weeks. Body composition varied with age; fat content increased from 12.7 to 15.9 to 19.8% for 6, 13, and 19 wk, respectively. The lowest body fat was observed for RBW pullets fed DIL (P = 0.003) at 19 weeks. Feeding DIL diets to HBW pullets could be done to increase the time spent eating and reduce their feeling of hunger without negative effects on body composition. However, its influence on behavior and BW uniformity was not proved. © The Author 2017. Published by Oxford University Press on behalf of Poultry Science Association.

  19. Forecasting interest rates with shifting endpoints

    DEFF Research Database (Denmark)

    Van Dijk, Dick; Koopman, Siem Jan; Wel, Michel van der

    2014-01-01

    We consider forecasting the term structure of interest rates with the assumption that factors driving the yield curve are stationary around a slowly time-varying mean or ‘shifting endpoint’. The shifting endpoints are captured using either (i) time series methods (exponential smoothing) or (ii......) long-range survey forecasts of either interest rates or inflation and output growth, or (iii) exponentially smoothed realizations of these macro variables. Allowing for shifting endpoints in yield curve factors provides substantial and significant gains in out-of-sample predictive accuracy, relative...... to stationary and random walk benchmarks. Forecast improvements are largest for long-maturity interest rates and for long-horizon forecasts....

  20. Method for numerical simulation of two-term exponentially correlated colored noise

    International Nuclear Information System (INIS)

    Yilmaz, B.; Ayik, S.; Abe, Y.; Gokalp, A.; Yilmaz, O.

    2006-01-01

    A method for numerical simulation of two-term exponentially correlated colored noise is proposed. The method is an extension of traditional method for one-term exponentially correlated colored noise. The validity of the algorithm is tested by comparing numerical simulations with analytical results in two physical applications