WorldWideScience

Sample records for experimentally based contact

  1. Experimental Validation of a Differential Variational Inequality-Based Approach for Handling Friction and Contact in Vehicle

    Science.gov (United States)

    2015-11-20

    terrain modeled using the discrete element method (DEM). Experimental Validation of a Differential Variational Inequality -Based Approach for Handling...COVERED 00-00-2015 to 00-00-2015 4. TITLE AND SUBTITLE Experimental Validation of a Differential Variational Inequality -Based Approach for...sinkage, and single wheel tests. 1.1. Modeling Frictional Contact Via Differential Variational Inequalities Consider a three dimensional (3D) system of

  2. Optical and vibrational properties of phosphorylcholine-based contact lenses-Experimental and theoretical investigations

    Science.gov (United States)

    Filipecka, Katarzyna; Miedziński, Rafał; Sitarz, Maciej; Filipecki, Jacek; Makowska-Janusik, Małgorzata

    2017-04-01

    The Raman, MIR and UV-vis spectroscopy have been used to characterize Omafilcon A material constructing the one of the Proclear family contact lenses. The Omafilcon A is hydrogel material composed of 2-hydroxyethyl methacrylate (HEMA) and 2-methacryloyloxyethyl phosphorylcholine (PC) polymers crosslinked with ethyleneglycol dimethacrylate (EGDMA). Vibrational and electronic properties of the Omafilcon A material were also investigated by quantum chemical calculations. Experimentally obtained Raman, MIR and optical spectra were compared to the theoretical ones calculated applying RHF and DFT methodology. The quantum chemical calculations were performed for isolated monomers of lenses compounds as well as for their dimers and trimers to elucidate the effect of Omafilcon A polymerization and the role of an individual components.

  3. Tea tree oil attenuates experimental contact dermatitis.

    Science.gov (United States)

    Wallengren, Joanna

    2011-07-01

    Herbs and minerals have been used in clinical dermatology for hundreds of years and herbal ingredients are becoming increasingly popular with the public in treatment of various dermatological conditions characterised by inflammation and pruritus. The aim of this study was to compare the efficacy of traditional topical therapeutic agents with a moderate potency topical glucocorticoid on experimental contact dermatitis and contact urticaria. The effects of ichthammol 10% pet, zinc oxide 20% pet, camphor 20% pet, levomenthol 10% pet, tea tree oil 20 or 50% and clobetason butyrate 0.05% ointment were studied in the following experimental models: elicitation of allergic contact dermatitis to nickel, irritant contact dermatitis to benzalkonium chloride, and in immediate reactions to histamine and benzoic acid (non-immunological contact utricaria) respectively. Delayed reactions were evaluated using a clinical scoring system and immediate reactions were estimated by planimetry. Histamine-induced pruritus was evaluated using VAS. Tea tree oil reduced allergic contact dermatitis by 40.5% (p = 0.003), zinc oxide by 17.4% (p = 0.04) and clobetason butyrate by 23.5% (p = 0.01). Zinc oxide reduced histamine induced flare by 18.5% (p = 0.01), ichthammol by 19.2% (p = 0.02) and clobetason butyrate by 44.1% (p = 0.02). Irritant contact dermatitis and non-immunological contact urticaria were not influenced by the pre-treatments. Pruritus induced by histamine also remained unchanged. In conclusion, tea tree oil seems to be a more effective anti-eczematic agent than zinc oxide and clobetasone butyrate, while clobetasone butyrate is superior to both ichthammol and zinc oxide in topical treatment of urticarial reactions.

  4. Experimental investigation on the electrical contact behavior of rolling contact connector

    Science.gov (United States)

    Chen, Junxing; Yang, Fei; Luo, Kaiyu; Zhu, Mingliang; Wu, Yi; Rong, Mingzhe

    2015-12-01

    Rolling contact connector (RCC) is a new technology utilized in high performance electric power transfer systems with one or more rotating interfaces, such as radars, satellites, wind generators, and medical computed tomography machines. Rolling contact components are used in the RCC instead of traditional sliding contacts to transfer electrical power and/or signal. Since the requirement of the power transmission is increasing in these years, the rolling electrical contact characteristics become more and more important for the long-life design of RCC. In this paper, a typical form of RCC is presented. A series of experimental work are carried out to investigate the rolling electrical contact characteristics during its lifetime. The influence of a variety of factors on the electrical contact degradation behavior of RCC is analyzed under both vacuum and air environment. Based on the surface morphology and elemental composition changes in the contact zone, which are assessed by field emission scanning electron microscope and confocal laser scanning microscope, the mechanism of rolling electrical contact degradation is discussed.

  5. Experimental Verification of a Systematic Method for Identifying Contact-Dynamics Model Parameters

    National Research Council Canada - National Science Library

    Ma, Ou; Kim, Jong; Martinez, Lucas

    2007-01-01

    This project is aimed at conducting an experimental test of a new and systematic method for identifying the key parameters of a general multiple-point contact dynamics model using a robotics-based experimental testbed...

  6. Duality based contact shape optimization

    DEFF Research Database (Denmark)

    Vondrák, Vít; Dostal, Zdenek; Rasmussen, John

    2001-01-01

    An implementation of semi-analytic method for the sensitivity analysis in contact shape optimization without friction is described. This method is then applied to the contact shape optimization.......An implementation of semi-analytic method for the sensitivity analysis in contact shape optimization without friction is described. This method is then applied to the contact shape optimization....

  7. Experimental investigations of contact-type damage nonlinearity

    Science.gov (United States)

    Klepka, A.; Dziedziech, K.; Pieczonka, Ł.; Adamczyk, M.; Staszewski, W. J.

    2017-05-01

    The problem of identification of non-linear phenomena associated with contact-type non-linearity is the subject of many research papers. The number of theoretical models describing the non-linear phenomena is constantly increasing. New capabilities of experimental verification and observation of these non-linear effects provide opportunities for a more accurate mathematical description of the non-linear behavior of contact interfaces. Better understanding of the non-linear related contact mechanisms can lead to more accurate numerical models of structures with contact-types defects, damage propagation and prediction algorithms and development of new methods for damage detection. This paper presents research on the non-linear acoustic phenomena in the presence of contact-type damage. Two test samples in contact are subject to vibro-acoustic modulation test. Non-linear spectral components were analysed and compared to the temperature changes generated as a results of the frictional forces.

  8. Influence of Thermal Contact Resistance of Aluminum Foams in Forced Convection: Experimental Analysis.

    Science.gov (United States)

    Guarino, Stefano; Di Ilio, Giovanni; Venettacci, Simone

    2017-08-05

    In this paper, the heat transfer performances of aluminum metal foams, placed on horizontal plane surface, was evaluated in forced convection conditions. Three different types of contacts between the sample and the heated base plate have been investigated: simple contact, brazed contact and grease paste contact. First, in order to perform the study, an ad hoc experimental set-up was built. Second, the value of thermal contact resistance was estimated. The results show that both the use of a conductive paste and the brazing contact, realized by means of a copper electro-deposition, allows a great reduction of the global thermal resistance, increasing de facto the global heat transfer coefficient of almost 80%, compared to the simple contact case. Finally, it was shown that, while the contribution of thermal resistance is negligible for the cases of brazed and grease paste contact, it is significantly high for the case of simple contact.

  9. Influence of Thermal Contact Resistance of Aluminum Foams in Forced Convection: Experimental Analysis

    Directory of Open Access Journals (Sweden)

    Stefano Guarino

    2017-08-01

    Full Text Available In this paper, the heat transfer performances of aluminum metal foams, placed on horizontal plane surface, was evaluated in forced convection conditions. Three different types of contacts between the sample and the heated base plate have been investigated: simple contact, brazed contact and grease paste contact. First, in order to perform the study, an ad hoc experimental set-up was built. Second, the value of thermal contact resistance was estimated. The results show that both the use of a conductive paste and the brazing contact, realized by means of a copper electro-deposition, allows a great reduction of the global thermal resistance, increasing de facto the global heat transfer coefficient of almost 80%, compared to the simple contact case. Finally, it was shown that, while the contribution of thermal resistance is negligible for the cases of brazed and grease paste contact, it is significantly high for the case of simple contact.

  10. Contact drying: a review of experimental and mechanistic modeling approaches.

    Science.gov (United States)

    Sahni, Ekneet Kaur; Chaudhuri, Bodhisattwa

    2012-09-15

    Drying is one of the most complex unit operations with simultaneous heat and mass transfer. The contact drying process is also not well understood as several physical phenomena occur concurrently. This paper reviews current experimental and modeling approaches employed towards a better understanding of the contact drying operation. Additionally, an overview of some fundamental aspects relating to contact drying is provided. A brief discussion of some model extensions such as incorporation of noncontact forces, interstitial fluids and attrition rate is also presented. Copyright © 2012 Elsevier B.V. All rights reserved.

  11. Contact Modelling in Resistance Welding, Part II: Experimental Validation

    DEFF Research Database (Denmark)

    Song, Quanfeng; Zhang, Wenqi; Bay, Niels

    2006-01-01

    Contact algorithms in resistance welding presented in the previous paper are experimentally validated in the present paper. In order to verify the mechanical contact algorithm, two types of experiments, i.e. sandwich upsetting of circular, cylindrical specimens and compression tests of discs...... with a solid ring projection towards a flat ring, are carried out at room temperature. The complete algorithm, involving not only the mechanical model but also the thermal and electrical models, is validated by projection welding experiments. The experimental results are in satisfactory agreement...... with the simulation prediction, showing the validity of the algorithm....

  12. Cryotrons based on a simultaneously distributed Josephson contact

    Energy Technology Data Exchange (ETDEWEB)

    Bakhtin, P.A.; Lapir, G.M.; Makhov, V.I.; Samus, A.N.; Semenov, V.K.; Tyablikov, A.V.

    1982-01-01

    The features of the construction of cryotrons based on an evenly distributed Josephson contact are examined. The possibility is demonstrated of producing cryotrons with an assigned form of the controlling characteristic through the spatial isolation of the transport and controlling streams. The theoretical and experimental controlling characteristics of cryotrons based on bridges of variable thickness with connectors of normal metal are cited. The proposed principles of cryotron production are also suitable for other types of Josephson contacts.

  13. Experimental Methods for Implementing Graphene Contacts to Finite Bandgap Semiconductors

    DEFF Research Database (Denmark)

    Meyer-Holdt, Jakob

    Present Ph.D. thesis describes my work on implanting graphene as electrical contact to finite bandgap semiconductors. Different transistor architectures, types of graphene and finite bandgap semiconductors have been employed. The device planned from the beginning of my Ph.D. fellowship...... contacts to semiconductor nanowires, more specifically, epitaxially grown InAs nanowires. First, we tried a top down method where CVD graphene was deposited on substrate supported InAs nanowires followed by selective graphene ashing to define graphene electrodes. While electrical contact between...... was a graphene-C60 monolayergraphene vertical transistor named the Carbon Burger. The fabrication of such device proved increasingly difficult to achieve and many experimental methods to handle graphene were implemented and improved in attempt to fabricate the Carbon Burger. In the end, a device platform...

  14. Scaling strategy of a new experimental rig for wheel-rail contact

    NARCIS (Netherlands)

    Naeimi, M.; Li, Z.; Dollevoet, R.P.B.J.

    2014-01-01

    A new small–scale test rig developed for rolling contact fatigue (RCF) investigations in wheel–rail material. This paper presents the scaling strategy of the rig based on dimensional analysis and mechanical modelling. The new experimental rig is indeed a spinning frame structure with multiple wheel

  15. Experimental Validation of the Invariance of Electrowetting Contact Angle Saturation

    NARCIS (Netherlands)

    Chevalliot, S.; Dhindsa, M.; Kuiper, S.; Heikenfeld, J.

    2011-01-01

    Basic electrowetting theory predicts that a continued increase in applied voltage will allow contact angle modulation to zero degrees. In practice, the effect of contact angle saturation has always been observed to limit the contact angle modulation, often only down to a contact angle of 60 to 70°.

  16. Design of high-pressure direct contact heater for promising power supply units: Experimental substantiation

    Science.gov (United States)

    Somova, E. V.; Shvarts, A. L.; Turkin, A. V.

    2016-11-01

    The results of experimental studies of superheated steam condensation on feed water jets in a highpressure, direct-contact heat exchanger are presented. Direct contact feed water heater (DCFWH) can be used in a dual-flow diagram of a steam-power unit with ultrasupercritical steam parameters (35 MPa, 700/720°C). The direct contact feed water heater is included in the flow diagram of the II circuit in a promising power unit; it provides feed water heating to 340°C in all maintenance and emergency operation modes of the unit. The reliability of the high-pressure direct contact heater operation in this flow diagram is of major importance in relation to the danger of lead solidification in the tube space of the steam generator. Technical requirements to the design of the high-pressure direct contact heater for increasing the heat exchange efficiency are formulated based on the results of earlier studies with steam-water mixture as the heating medium. The results of studies of superheated steam condensation on jets presented in this study testify that feed water is additionally heated to the required temperature at the output of the installation. The influence of initial feed water parameters (outflow velocity and temperature) on the jet heating length is elucidated. The numerical approximation of the experimental data for determination of the jet heating length in the nominal and partial power unit loads is obtained. The results of the calculations are used to simplify the design of the water-supplying element for the direct contact feed water heater. The proposed design of direct contact feed water heater is characterized by simplicity and low metal intensity, which provides the installation reliability at the considered pressure level due to the minimum number of structural elements.

  17. Experimental study of contact edge roughness on sub-100 nm various circular shapes

    Science.gov (United States)

    Lee, Tae Y.; Ihm, Dongchul; Kang, Hyo C.; Lee, Jum B.; Lee, Byoung H.; Chin, Soo B.; Cho, Do H.; Song, Chang L.

    2005-05-01

    The measurement of edge roughness has become a hot issue in the semiconductor industry. Especially the contact roughness is being more critical as design rule shrinks. Major vendors offer a variety of features to measure the edge roughness in their CD-SEMs. For the line and space patterns, features such as Line Edge Roughness (LER) and Line Width Roughness (LWR) are available in current CD-SEMs. However the features currently available in commercial CD-SEM cannot provide a proper solution in monitoring the contact roughness. We had introduced a new parameter R, measurement algorithm and definition of contact edge roughness to quantify CER and CSR in previous paper. The parameter, R could provide an alternative solution to monitor contact or island pattern roughness. In this paper, we investigated to assess optimum number of CD measurement (1-D) and fitting method for CER or CSR. The study was based on a circular contact shape. Some new ideas to quantify CER or CSR were also suggested with preliminary experimental results.

  18. An experimental investigation on contact compression lap splice in circular columns

    Directory of Open Access Journals (Sweden)

    Hamed S. Askar

    2016-08-01

    The objective of the present investigation is to study the influence of splice length, volume of transverse reinforcement and end bearing condition on the behavior of compression lap splice. The conducted investigation included experimental tests of nine circular columns under uniaxial compression loads. All spliced bars were in contact with each other and with constant concrete cover. Based on the experimental investigation and test results, concluding remarks have been drawn, based on which a design simplified equation for splice length in compression has been developed. A correlation between the experimental and calculated results of the author specimens and other results available in literature, showed a good agreement. Also, the formulas adapted by different codes for predicting the compression lap splice length have been checked with the proposed equation.

  19. Experimental Study on Dry Friction Damping Characteristics of the Steam Turbine Blade Material with Nonconforming Contacts

    Directory of Open Access Journals (Sweden)

    Jun Wu

    2015-01-01

    Full Text Available An experiment system has been established to study the dry friction damping dynamic characteristics of the steam turbine blade material 1Cr13. The friction dynamic characteristics of the specimens with nonconforming contact surfaces are measured under different parameters. The experiment results are compared with that of the macroslip hysteresis model and the Mindlin microslip friction model in detail. The results show that the experimental result of the tangential contact stiffness is in good agreement with that of the theory result based on the fractal theory and the Hertz contact theory by Jiang et al., 2009. The dimensionless equivalent stiffness and equivalent damping obtained by the macroslip hysteresis model agree well with the experimental results when relative motion is relatively large. However, the results of the macroslip hysteresis model differ a lot from the experimental results when relative motion is relatively small. Compared with the macroslip hysteresis model, the Mindlin microslip friction model can predict the dimensionless equivalent stiffness and equivalent damping accurately during the whole measurement range. The linear regularities of dimensionless equivalent stiffness and equivalent damping are obtained, which decrease the difficulty of building the vibration analysis model of the blade with sufficient accuracy.

  20. Experimental Tooling for Contact Stress Measurement in Bulk Metal Forming Processes

    Science.gov (United States)

    Vilotić, Dragiša; Plančak, Miroslav

    2011-01-01

    Knowledge of contact stresses in metal forming operations is essential not only for optimal die design, but also for theoretical and numerical analysis of the metal forming processes. Determination of contact stresses can be performed theoretically and experimentally. This paper presents a tool construction with built-in pin-load cells for experimental determination of contact stresses and friction coefficient at upsetting of prismatic specimen with cylindrical dies. This construction allows measurement of contact stresses in any point of the contact surface of specimen, due to adjustable location of pin-load cells. The adjustments are performed by turning cylindrical dies around its own axis in combination with the change of axial position of the specimen. Experimental determination of contact stresses in upsetting of Ck35 prismatic specimens using cylindrical tools was performed at the Laboratory for technology of plasticity, FTN Novi Sad.

  1. Experimental consideration of contact resistance related to modified configuration of line contact; Sen sessyokusi no sessyoku keitai ni tomonau sessyoku teiko no jikkenteki kosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Aichi, H. [Daido Institute of Technology, Aichi (Japan); Miyachi, I. [Aichi Institute of Technology, Aichi (Japan)

    1997-06-20

    The contact form of electric contact which is used on a switchgear is roughly divided to a point, a line and a plane contact. Among them, a point contact is considered as the foundation of contact form and according to the contact structures such as spherical surface vs. spherical surface and spherical surface vs. plane and so on, one of the minute circular contacts, so called a point contact, is formed. On the most of the connectors and the circuit-breakers, the line or the plane contact member is applied. Authors have been developed an unique contact model be able to measure the contact resistance of any form. In this model, it is available to select the size, the member and the configuration of contact spots by macroscopic arrangement of some metal electrodes immersed in electrolyte solution of dilute sulfuric acid. In this paper, the contact resistance of a case that changes from line to plane contact and that of several line contacts in parallel are studied. The experimental results obtained clarify that the characteristics of contact resistance changed form line to plane contact are equivalent to those of a point contact, the contact resistance of line contacts in parallel has the same characteristics as that of a long line contact and so forth. 9 refs., 8 figs.

  2. Electron tunneling through molecule-electrode contacts of single alkane molecular junctions: experimental determination and a practical barrier model.

    Science.gov (United States)

    Wang, Kun; Xu, Bingqian

    2016-04-14

    An advanced understanding of the molecule-electrode contact interfaces of single-molecule junctions is a necessity for real world application of future single-molecule devices. This study aims to elucidate the change in the contact tunnelling barrier induced by junction extension and how this change affects the resulting junction conductance. The contact barrier of Au-octanedithiol/octanediamine-Au junctions was studied under triangle (TRI) mechanical modulations using the modified scanning tunneling microscopy (STM) break junction technique. The experimental results reveal that as the junction separation extends, the contact barrier of octanedithiol follows a unique trend, a linear increase followed by a plateau in barrier height, which is in contrast to that of octanediamine, a nearly rectangle barrier. We propose a modified contact barrier model for the unique barrier shape of octanedithiol, based on which the calculation agrees well with the experimental data. This study shows unprecedented experimental features of the molecule-electrode contact barrier of single-molecule junctions and provides new insights into the nature of contact effect in determining electron transport through single-molecule junctions.

  3. An Experimental Study of the Electrical Contact Resistance in Resistance Welding

    DEFF Research Database (Denmark)

    Song, Quanfeng; Zhang, Wenqi; Bay, Niels

    2005-01-01

    Electrical contact resistance is of critical importance in resistance welding. In this article, the contact resistance is experimentally investigated for welding mild steel, stainless steel, and aluminum to themselves. A parametric study was carried out on a Gleeble® machine, investigating...

  4. Experimental Comparison of the Behavior between Base Oil and Grease Starvation Based on Inlet Film Thickness

    Directory of Open Access Journals (Sweden)

    D. Kostal

    2017-03-01

    Full Text Available This paper deals with the experimental study of an elastohydrodynamic contact under conditions of insufficient lubricant supply. Starvation level of this type of the contact may be experimentally determined based on the position of the meniscus, but this way can't determine all levels of starvation. Consequent development in the field of tribology achieved theoretical model that can determine all levels of starvation by dependency on the thickness of the lubricant film entering the contact, but it is difficult for experimental verification. The main goal of this work is an experimental study and description of the behavior of the elastohydrodynamic contact with controlled thickness of the lubricant film at the contact input. Contact was lubricated by the base oil and the grease and compared. Results were surprising because the only differences between oil and grease were observed for more viscous lubricants at thicker film layer entering to the contact.

  5. Ohmic contacts to InN-based materials

    Directory of Open Access Journals (Sweden)

    Sai P. O.

    2016-10-01

    Full Text Available The key aspects of ohmic contact formation to InN-based materials were investigated. Detailed analysis of studies conducted over the past three decades, allows determining the basic principles of such contacts. The contact structure properties and optimal conditions for them are presented. Different types of metallization are considered, the advantages and disadvantages of each are determined, including the basic requirements that such contact must meet. There is emphasis on the using multilayer metallization with the barrier layers. In the case of the InAlN/GaN systems, the general approaches of forming ohmic contacts were considered.

  6. EXPERIMENTAL INVESTIGATION OF THE ADHESIVE CONTACT WITH ELASTOMERS: EFFECT OF SURFACE ROUGHNESS

    Directory of Open Access Journals (Sweden)

    Lars Voll

    2015-04-01

    Full Text Available Adhesion between an elastomer and a steel indenter was studied experimentally and described with an analytical model. Cylindrical indenters having different roughness were brought into contact with an elastomer with various normal forces. After a “holding time”, the indenter was pulled with a constant velocity, which was the same in all experiments. We have studied the regime of relatively small initial normal loadings, large holding times and relatively large pulling velocities, so that the adhesive force did not depend on the holding time but did depend on the initially applied normal force and was approximately proportional to the pulling velocity. Under these conditions, we found that the adhesive force is inversely proportional to the roughness and proportional to the normal force. For the theoretical analysis, we used a previously published MDR-based model.

  7. Experimental Investigations of Thermal Transport in Carbon Nanotubes, Graphene and Nanoscale Point Contacts

    Science.gov (United States)

    Pettes, Michael Thompson

    As silicon-based transistor technology continues to scale ever downward, anticipation of the fundamental limitations of ultimately-scaled devices has driven research into alternative device technologies as well as new materials for interconnects and packaging. Additionally, as power dissipation becomes an increasingly important challenge in highly miniaturized devices, both the implementation and verification of high mobility, high thermal conductivity materials, such as low dimensional carbon nanomaterials, and the experimental investigation of heat transfer in the nanoscale regime are requisite to continued progress. This work furthers the current understanding of structure-property relationships in low dimensional carbon nanomaterials, specifically carbon nanotubes (CNTs) and graphene, through use of combined thermal conductance and transmission electron microscopy (TEM) measurements on the same individual nanomaterials suspended between two micro-resistance thermometers. Through the development of a method to measure thermal contact resistance, the intrinsic thermal conductivity, kappa, of multi-walled (MW) CNTs is found to correlate with TEM observed defect density, linking phonon-defect scattering to the low kappa in these chemical vapor deposition (CVD) synthesized nanomaterials. For single- (S) and double- (D) walled (W) CNTs, the kappa is found to be limited by thermal contact resistance for the as-grown samples but still four times higher than that for bulk Si. Additionally, through the use of a combined thermal transport-TEM study, the kappa of bi-layer graphene is correlated with both crystal structure and surface conditions. Theoretical modeling of the kappa temperature dependence allows for the determination that phonon scattering mechanisms in suspended bi-layer graphene with a thin polymeric coating are similar to those for the case of graphene supported on SiO2. Furthermore, a method is developed to investigate heat transfer through a nanoscale

  8. Experimental consideration on the contact resistance caused by the distribution of contact spots with the contact model using electrolyte bath; Denkai yokuso wo mochiita sesshoku model ni yoru sesshokuten no bunpu to sesshoku teiko tokusei ni kansuru jikkenteki kosatsu

    Energy Technology Data Exchange (ETDEWEB)

    Aichi, H. [Daido Institute of Technology, Aichi (Japan); Miyachi, I. [Aichi Institute of Technology, Aichi (Japan)

    1996-09-20

    Electric contact members are classified by the form such as a point, a line, and a plane. Particularly, the point contact member which makes a small circular contact spot is basis of the contact form. Also, the plane contact member will make many contact spots which are different in size and distributing over the contacting portion. Authors have been developing the contact model to measure the contact resistance. In this model, it is available to select the size, the number, and the arrangement of contact spots by the macroscopical contact spots which are formed with some metal electrodes arranged in electrolyte solution of dilute sulfuric acid. In this paper, the fundamental characteristics of the contact resistance caused by the construction of current are investigated with 1 to 3 contact spot models. Then the relations between the contact resistance and the distribution of the contact spots are examined with 2 to 9 multi-contact spot models. As the results, it is cleared that the proposed contact model presents the successful experimental method for the analysis of the contact resistance. 9 refs., 8 tabs.

  9. Advances in protein contact map prediction based on machine learning.

    Science.gov (United States)

    Xie, Jiang; Ding, Wang; Chen, Luonan; Guo, Qiang; Zhang, Wu

    2015-01-01

    A protein contact map is a simplified, two-dimensional version of the three-dimensional protein structure. Protein contact map is proved to be crucial in forming the three-dimensional structure. Contact map prediction has now become an indispensable and promising intermediate step towards final three-dimensional structure prediction, while directed sequence-structure prediction hits its bottlenecks. In this article, different evaluation scores of prediction efficiency are compared. Next, the state of the art and future perspectives of contact map methods are reviewed and special attention is paid to those relying on machine learning algorithms. Details of neural network based methods as well as a list of machine learning based methods are given. Finally, bottlenecks and potential improvements of contact map predictions are discussed.

  10. Experimental methodology of contact edge roughness on sub-100-nm pattern

    Science.gov (United States)

    Lee, Tae Yong; Ihm, Dongchul; Kang, Hyo Chun; Lee, Jun Bum; Lee, Byoung-Ho; Chin, Soo-Bok; Cho, Do-Hyun; Kim, Yang Hyong; Yang, Ho Dong; Yang, Kyoung Mo

    2004-05-01

    The measurement of edge roughness has become a hot issue in the semiconductor industry. Major vendors offer a variety of features to measure the edge roughness in their CD-SEMs. However, most of the features are limited by the applicable pattern types. For the line and space patterns, features such as Line Edge Roughness (LER) and Line Width Roughness (LWR) are available in current CD-SEMs. The edge roughness is more critical in contact process. However the measurement of contact edge roughness (CER) or contact space roughness (CSR) is more complicated than that of LER or LWR. So far, no formal standard measurement algorithm or definition of contact roughness measurement exists. In this article, currently available features are investigated to assess their representability for CER or CSR. Some new ideas to quantify CER and CSR were also suggested with preliminary experimental results.

  11. Dynamic modeling and experimental validation for direct contact membrane distillation (DCMD) process

    KAUST Repository

    Eleiwi, Fadi

    2016-02-01

    This work proposes a mathematical dynamic model for the direct contact membrane distillation (DCMD) process. The model is based on a 2D Advection–Diffusion Equation (ADE), which describes the heat and mass transfer mechanisms that take place inside the DCMD module. The model studies the behavior of the process in the time varying and the steady state phases, contributing to understanding the process performance, especially when it is driven by intermittent energy supply, such as the solar energy. The model is experimentally validated in the steady state phase, where the permeate flux is measured for different feed inlet temperatures and the maximum absolute error recorded is 2.78 °C. Moreover, experimental validation includes the time variation phase, where the feed inlet temperature ranges from 30 °C to 75 °C with 0.1 °C increment every 2min. The validation marks relative error to be less than 5%, which leads to a strong correlation between the model predictions and the experiments.

  12. An experimental study on mother-infant skin-to-skin contact in full-terms

    NARCIS (Netherlands)

    Beijers, R.; Cillessen, L.J.G.; Zijlmans, M.A.C.

    2016-01-01

    In premature infants, daily skin-to-skin contact (SSC) has various beneficial effects on the health of the infant and the mother. These beneficial effects might extend to full-term infants. This experimental within-subject study examines the immediate effects of SSC on full-terms’ cortisol

  13. Experimental characterization of electrochemically polymerized polycarbazole film and study of its behavior with different metals contacts

    Science.gov (United States)

    Srivastava, Aditi; Chakrabarti, P.

    2017-12-01

    In this paper, we present the method of fabrication, experimental characterization, and comparison of electrical parameters of semiconducting polycarbazole film with different rectifying metals contacts. Electrochemical polymerization and deposition of organic semiconductor, i.e., polycarbazole on ITO-coated glass substrate, were performed using an electrochemical workstation. Experimental characterization of the prepared polymer film was done in respect of morphology, absorption, bandgap, and thickness. The stability and electro-activity of polycarbazole film were verified by the cyclic voltammetric method. Study of the behavior of prepared polycarbazole film with the different metals contacts such as Aluminum, Copper, Tungsten, and Tin has been done using semiconductor device analyzer. Various electrical parameters such as barrier height, ideality factor, and reverse saturation current have been extracted with different metal contacts, and the values were compared and contrasted. The nature of I- V characteristic of polycarbazole film in non-contact mode has also been analyzed using scanning tunneling microscope. The rectifying I- V characteristics obtained with different metals contacts have also been validated by the simulation on Deckbuild platform of the of ATLAS® software tool from Silvaco Inc.

  14. An Experimental Study on Heat Conduction and Thermal Contact Resistance for the AlN Flake

    Directory of Open Access Journals (Sweden)

    Huann-Ming Chou

    2013-01-01

    Full Text Available The electrical technology has been a fast development over the past decades. Moreover, the tendency of microelements and dense division multiplex is significantly for the electrical industries. Therefore, the high thermal conductible and electrical insulating device will be popular and important. It is well known that AlN still maintains stablility in the high temperature. This is quite attractive for the research and development department. Moreover, the thermal conduct coefficient of AlN is several times larger than the others. Therefore, it has been thought to play an important role for the radiator of heat source in the future. Therefore, this paper is focused on the studies of heat conduction and thermal contact resistance between the AlN flake and the copper specimens. The heating temperatures and the contact pressures were selected as the experimental parameters. According to the experimental results, the materials are soft and the real contact areas between the interfaces significantly increase under higher temperatures. As a result, the thermal contact resistance significantly decreases and the heat transfer rate increases with increasing the heating temperature or the contact pressures.

  15. Experimental investigation and numerical simulation of triggered vacuum arc behavior under TMF/RMF-AMF contact

    Science.gov (United States)

    Wang, Lijun; Deng, Jie; Qin, Kang; Zhang, Xiao; Jia, Shenli

    2016-06-01

    A series of triggering experiments was carried out to investigate the characteristics of vacuum arc controlled by TMF/RMF-AMF contacts. During all the experiments, the current ranged from 5-20 kA (rms) and both the arc appearance and behavior of cathode spots were captured by high-speed camera with corresponding arc current and arc voltage. A 3D steady magnetohydrodynamics (MHD) model was built to simulate and analyze the vacuum arc behavior under TMF/RMF-AMF contacts, and arc plasma parameters were calculated based on the above model. The experimental results showed that arc deflection was visible under both low and high current. Under high current, arc core formed, which meant the arc contracted significantly. In addition, the anode became much more active under high current. The behavior of the cathode spots showed that they split themselves into other new cathode spots. Under high current, the bulk of the spots rotated along a clockwise direction on a transverse magnetic field (TMF) plate, which caused much noise and oscillation in the arc voltage. The simulation results show that ions are likely to gather on the branches of the TMF plate on the anode plane, as a result of the effects between the electromagnetic force and pressure gradient of the arc plasma. The current contracts in the center of the TMF plate on the cathode which was due to the thin connecting rod there. The anode contraction of the current is caused by the Hall effect. Ions move along a clockwise direction on the TMF plate, which is driven by Ampere force. The current contraction resulted in significant melting in the center of the cathode surface while the other region suffered from uniform melting. The melting caused by the anode contraction is more significant than that of the cathode.

  16. Mass spectrometry-based proteomic analyses of contact lens deposition

    OpenAIRE

    Green-Church, Kari B.; Nichols, Jason J.

    2008-01-01

    Purpose The purpose of this report is to describe the contact lens deposition proteome associated with two silicone hydrogel contact lenses and care solutions using a mass spectrometric-based approach. Methods This was a randomized, controlled, examiner-masked crossover clinical trial that included 48 participants. Lenses and no-rub care solutions evaluated included galyfilcon A (Acuvue Advance, Vistakon Inc., Jacksonville, FL), lotrafilcon B (O2 Optix, CIBA Vision Inc., Duluth, GA), AQuify (...

  17. Novel vertical silicon photodiodes based on salicided polysilicon trenched contacts

    Energy Technology Data Exchange (ETDEWEB)

    Kaminski, Yelena [Department of Chemical Engineering, Technion, Haifa (Israel); TowerJazz Ltd. Migdal Haemek (Israel); Shauly, Eitan [TowerJazz Ltd. Migdal Haemek (Israel); Paz, Yaron, E-mail: paz@tx.technion.ac.il [Department of Chemical Engineering, Technion, Haifa (Israel)

    2015-12-07

    The classical concept of silicon photodiodes comprises of a planar design characterized by heavily doped emitters. Such geometry has low collection efficiency of the photons absorbed close to the surface. An alternative, promising, approach is to use a vertical design. Nevertheless, realization of such design is technologically challenged, hence hardly explored. Herein, a novel type of silicon photodiodes, based on salicided polysilicon trenched contacts, is presented. These contacts can be prepared up to 10 μm in depth, without showing any leakage current associated with the increase in the contact area. Consequently, the trenched photodiodes revealed better performance than no-trench photodiodes. A simple two dimensional model was developed, allowing to estimate the conditions under which a vertical design has the potential to have better performance than that of a planar design. At large, the deeper the trench is, the better is the vertical design relative to the planar (up to 10 μm for silicon). The vertical design is more advantageous for materials characterized by short diffusion lengths of the carriers. Salicided polysilicon trenched contacts open new opportunities for the design of solar cells and image sensors. For example, these contacts may passivate high contact area buried contacts, by virtue of the conformity of polysilicon interlayer, thus lowering the via resistance induced recombination enhancement effect.

  18. On the Rotor to Stator Contact Dynamics with Impacts and Friction - Theoretical and Experimental Study

    DEFF Research Database (Denmark)

    Lahriri, Said

    surface of the stator, and thereby traversing the full extent of the clearance. Normal and friction forces are exerted on the rotor at each impact and rubs. These particular forces can sustain the rotor in a persistent backward dry whirl or whip motion. In that case, the friction force plays a significant......The contact between a rotor and its stator can in some cases be considered as a serious malfunction that may lead to catastrophic failure. This major threat arises normally from full annular dry friction backward whirl and whip motion where the rotor runs and rubs at a high frequency on the inner...... role during dry contact since it changes the precession of the rotor motion. This thesis gives a comprehensive experimental and theoretical study on the rotor to stator contact dynamics, under the in uence of dry friction. Different backward full annular dry motions are generated and analyzed...

  19. Experimental Investigation of Dynamic Wetting Models: Interface Shapes and Velocity Fields Near the Moving Contact Line.

    Science.gov (United States)

    Chen, Qun

    Dynamic wetting is the displacement of one fluid by another immiscible fluid across a solid surface as it spreads. Such processes control many natural phenomena and technological applications. The spreading dynamics of macroscopic fluid bodies are dictated by the hydrodynamics in a microscopic region near the moving contact line. Analytical models have been developed to describe the interface shape and velocity field near the contact line. Using videomicroscopy, particle image velocimetry, and digital image analysis, we make simultaneous measurements of the fluid/fluid interface shape and fluid flow field within the first few hundred microns near a moving contact line. Our experiments establish the validity and limitations of these analytical models. This work extensively tests assumptions embedded in the models and sets up bounds on the parameter space in which the models are valid. The models successfully describe the hydrodynamics near the contact line up to a capillary number ~0.10 but break down at higher capillary number. We determine the origins of this breakdown. We also carefully probe those regions near the contact line where the interface shape and flow field are independent of the macroscopic geometry. Our experimental technique provides a means of obtaining such material-dependent,, geometry-independent information about the system. Such information serves as boundary conditions transferable among different macroscopic geometries. It is an essential ingredient for numerical calculations of the spreading dynamics. The work reported in this thesis sets the stage for predictive modeling of dynamic wetting.

  20. Touchscreen surface based on interaction of ultrasonic guided waves with a contact impedance

    Science.gov (United States)

    Quaegebeur, Nicolas; Masson, Patrice; Beaudet, Nicolas; Sarret, Philippe

    2017-04-01

    In the present paper, a touchscreen device is proposed, based on guided wave reflection and transmission induced by the presence of an object. The principle uses the advantages of other acoustic waves devices in terms of simplicity and applicability to any thin surface but is not subject to classical drawbacks (single-touch, sensitivity to scratches or contaminant, impossibility to follow motion of contact point). The theoretical interaction of guided waves with a contact impedance are first derived in order to define the requirements of the sensor in terms of frequency range, mode, sensor type and location, and embedded electronics. Design criteria and experimental validation on a small prototype (300 x 300 mm) are proposed to demonstrate the potential of the approach for simple, robust and reliable contact detection and contact pressure estimation of point-like or extended objects for consumer electronics or biomedical applications.

  1. Reviews of experimental studies on various geometrical contact modes of vapor explosions

    Energy Technology Data Exchange (ETDEWEB)

    Park, Hyun-sun; Yamano, Norihiro; Maruyama, Yu; Moriyama, Kiyofumi; Kudo, Tamotsu; Sugimoto, Jun [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    1996-11-01

    The review aims to collect the available experimental information mainly on the stratified and injection modes of vapor explosions and identify areas requiring additional research. A substantial number of works have been performed on the pouring mode of vapor explosions since the pouring mode of vapor explosions is considered to be the most predominant geometric conditions in hypothetical severe accidents in nuclear power plants. However, other types of mode of vapor explosions are relatively less focused. Because of their different sequential progresses and mechanisms of vapor explosions especially at the initial stage of the event, it is essential to identify their mechanisms to make more clear understanding and eventually to provide a methodology for prevention in these types of vapor explosions. It has been recognized that the development of scaling methodologies in the experimental view points to bridge the experiment to prototypic conditions is of great importance under the circumstances of no relevant theoretical models in vapor explosion phenomena. In the sense, it will be useful to perform vapor explosion experiments in an experimental facility which can not only well control the initial and boundary experimental conditions, but also directly measure the energetics of vapor explosions. In particular, it is recommended to study the vapor explosion phenomena in such a facility which has additional capability of providing various contact modes to identify their mechanisms and to scale the energetics of vapor explosions in various contact modes in terms of a precisely measured conversion ratio. (J.P.N.). 51 refs.

  2. Flexible experimental FPGA based platform

    DEFF Research Database (Denmark)

    Andersen, Karsten Holm; Nymand, Morten

    2016-01-01

    This paper presents an experimental flexible Field Programmable Gate Array (FPGA) based platform for testing and verifying digital controlled dc-dc converters. The platform supports different types of control strategies, dc-dc converter topologies and switching frequencies. The controller platform...... interface supporting configuration and reading of setup parameters, controller status and the acquisition memory in a simple way. The FPGA based platform, provides an easy way within education or research to use different digital control strategies and different converter topologies controlled by an FPGA...

  3. Experimental analysis of the Portevin Le Chatelier effect by means of full field non contact techniques

    Science.gov (United States)

    Curã, F.; Matteis, P.; Scavino, G.; Sesana, R.

    2010-06-01

    Strain related phenomena in materials showing the Portevin Le Chatelier (PLC) effect are investigated when subjected to loading conditions both in elastic and in plastic field. Two experimental techniques for strain measurements are compared, thermography and optical strain measurement, both non contact, non destructive and full field. Two materials have been tensile tested with several test speeds. Each specimen has been observed and test evolution has contemporaneously been acquired with both video and thermotracer. Each test has been repeated several times. Aim of this research is to investigate how these experimental techniques may quantitatively describe the above described phenomena. Experimental data are useful to calibrate models describing the mechanical behaviour of materials (i.e. constitutive laws, damage models, etc.) and to focus phenomena which take place during load and corresponding strain phases.

  4. Experimental analysis of the Portevin Le Chatelier effect by means of full field non contact techniques

    Directory of Open Access Journals (Sweden)

    Sesana R.

    2010-06-01

    Full Text Available Strain related phenomena in materials showing the Portevin Le Chatelier (PLC effect are investigated when subjected to loading conditions both in elastic and in plastic field. Two experimental techniques for strain measurements are compared, thermography and optical strain measurement, both non contact, non destructive and full field. Two materials have been tensile tested with several test speeds. Each specimen has been observed and test evolution has contemporaneously been acquired with both video and thermotracer. Each test has been repeated several times. Aim of this research is to investigate how these experimental techniques may quantitatively describe the above described phenomena. Experimental data are useful to calibrate models describing the mechanical behaviour of materials (i.e. constitutive laws, damage models, etc. and to focus phenomena which take place during load and corresponding strain phases.

  5. Development of an IMU-based foot-ground contact detection (FGCD) algorithm.

    Science.gov (United States)

    Kim, Myeongkyu; Lee, Donghun

    2017-03-01

    It is well known that, to locate humans in GPS-denied environments, a lower limb kinematic solution based on Inertial Measurement Unit (IMU), force plate, and pressure insoles is essential. The force plate and pressure insole are used to detect foot-ground contacts. However, the use of multiple sensors is not desirable in most cases. This paper documents the development of an IMU-based FGCD (foot-ground contact detection) algorithm considering the variations of both walking terrain and speed. All IMU outputs showing significant changes on the moments of foot-ground contact phases are fully identified through experiments in five walking terrains. For the experiment on each walking terrain, variations of walking speeds are also examined to confirm the correlations between walking speed and the main parameters in the FGCD algorithm. As experimental results, FGCD algorithm successfully detecting four contact phases is developed, and validation of performance of the FGCD algorithm is also implemented. Practitioner Summary: In this research, it was demonstrated that the four contact phases of Heel strike (or Toe strike), Full contact, Heel off and Toe off can be independently detected regardless of the walking speed and walking terrain based on the detection criteria composed of the ranges and the rates of change of the main parameters measured from the Inertial Measurement Unit sensors.

  6. A fractal contact theory based model for bolted connection looseness monitoring using piezoceramic transducers

    Science.gov (United States)

    Huo, Linsheng; Wang, Furui; Li, Hongnan; Song, Gangbing

    2017-10-01

    In this paper, based on the fractal contact theory, a new analytical model for bolted joints is proposed to monitor bolt looseness by using a pair of piezoceramic transducers for ultrasonic wave generation and detection. The time reversal method is used to obtain the focused signal peak amplitude during ultrasonic wave propagation through bolt connection surface. The influence of bolt load on the actual contact area of the bolted joint surface is determined by the fractal contact theory, and the finite element method is applied to obtain the relationship between the actual contact area and the focused signal peak amplitude. The focused signal peak obtained through the time reversal method increases with the increase of applied axial load before saturation. The investigation proposed in this paper is based on the inherent contact mechanism between the two contact surfaces, and achieves more accurate quantitative monitoring of bolt looseness. Finally, a comparison of the predicted and experimental results shown validates the proposed model in this paper.

  7. An experimental study of a three-phase, direct-contact heat exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Siqueiros, J.; Bonilla, O. [Unidad Energias No-Convencionales, Div. Energias Alternas e Informatica, Cuernavaca (Mexico)

    1999-05-01

    An experimental pilot scale three-phase, direct-contact heat exchanger was constructed and tested. Experiments were performed using normal pentane as the dispersed phase and water as the continuous phase. The inlet water temperatures ranged from 75 to 88degC, and the inlet pentane temperatures varied from 23 to 38degC. The volumetric heat transfer coefficient, hold-up and heat flow-rate are functions of pentane mass flow-rate. For high pentane/water volumetric flow ratios flooding was reached. Before reaching flooding conditions, accumulation of liquid pentane at the top of the active volume was found. The experimental volumetric heat transfer coefficient values are on average 30% greater than those estimated with the correlation previously proposed by Jacobs. (Author)

  8. Experimental quantification of dynamic forces and shaft motion in two different types of backup bearings under several contact conditions

    DEFF Research Database (Denmark)

    Lahriri, Said; Santos, Ilmar

    2013-01-01

    This paper treats the experimental study on a shaft impacting its stator for different cases. The paper focuses mainly on the measured contact forces and the shaft motion in two different types of backup bearings. As such, the measured contact forces are thoroughly studied. These measured contact...... forces enable the hysteresis loops to be computed and analyzed. Consequently, the contact forces are plotted against the local deformation in order to assess the contact force loss during the impacts. The shaft motion during contact with the backup bearing is verified with a two-sided spectrum analyses...... the first critical speed, the investigation revealed that different paths initiated the onset of backward whip and whirling motion. In order to improve the whirling and the full annular contact behavior, an unconventional pinned backup bearing is realized. The idea is to utilize pin connections that center...

  9. Development of 3D online contact measurement system for intelligent manufacturing based on stereo vision

    Science.gov (United States)

    Li, Peng; Chong, Wenyan; Ma, Yongjun

    2017-10-01

    In order to avoid shortcomings of low efficiency and restricted measuring range exsited in traditional 3D on-line contact measurement method for workpiece size, the development of a novel 3D contact measurement system is introduced, which is designed for intelligent manufacturing based on stereo vision. The developed contact measurement system is characterized with an intergarted use of a handy probe, a binocular stereo vision system, and advanced measurement software.The handy probe consists of six track markers, a touch probe and the associated elcetronics. In the process of contact measurement, the hand probe can be located by the use of the stereo vision system and track markers, and 3D coordinates of a space point on the workpiece can be mearsured by calculating the tip position of a touch probe. With the flexibility of the hand probe, the orientation, range, density of the 3D contact measurenent can be adptable to different needs. Applications of the developed contact measurement system to high-precision measurement and rapid surface digitization are experimentally demonstrated.

  10. New LMI based gain-scheduling control for recovering contact-free operation of a magnetically levitated rotor

    Science.gov (United States)

    Wang, M.; Cole, M. O. T.; Keogh, P. S.

    2017-11-01

    A new approach for the recovery of contact-free levitation of a rotor supported by active magnetic bearings (AMB) is assessed through control strategy design, system modelling and experimental verification. The rotor is considered to make contact with a touchdown bearing (TDB), which may lead to entrapment in a bi-stable nonlinear response. A linear matrix inequality (LMI) based gain-scheduling H∞ control technique is introduced to recover the rotor to a contact-free state. The controller formulation involves a time-varying effective stiffness parameter, which can be evaluated in terms of forces transmitted through the TDB. Rather than measuring these forces directly, an observer is introduced with a model of the base structure to transform base acceleration signals using polytopic coordinates for controller adjustment. Force transmission to the supporting base structure will occur either through an AMB alone without contact, or through the AMB and TDB with contact and this must be accounted for in the observer design. The controller is verified experimentally in terms of (a) non-contact robust stability and vibration suppression performance; (b) control action for contact-free recovery at typical running speeds with various unbalance and TDB misalignment conditions; and (c) coast-down experimental tests. The results demonstrate the effectiveness of the AMB control action whenever it operates within its dynamic load capacity.

  11. An Experimental Model to Study the Impact of Lipid Oxidation on Contact Lens Deposition In Vitro.

    Science.gov (United States)

    Schuett, Burkhardt S; Millar, Thomas J

    2017-09-01

    This study was to establish a controlled in vitro test system to study the effect of lipid oxidation on lipid deposition on contact lenses. Fatty acids with varying degree of unsaturation were oxidized using the Fenton reaction. The degree of lipid oxidation and the lipid moieties formed during the oxidation were identified and estimated by various lipid staining techniques following separation with thin-layer chromatography, and by measuring thiobarbituric acid reactive substances or peroxides in solution. Two different silicone hydrogel-based contact lenses (Balafilcon A and Senofilcon A) were incubated with fatty acids laced with radioactive tracer oxidized to varying degrees, and the amount of lipid deposition was measured using unoxidized lipid samples as controls. The Fenton reaction together with the analytical methods to analyze the lipid oxidation can be used to control oxidation of lipids to a desired amount. In general, saturated fatty acids are not oxidized, the monounsaturated oleic acid produced peroxides while poly-unsaturated lipids initially produced peroxides and then fragmented into reactive aldehydes. Incubation with mildly oxidized lipids (most likely lipid peroxides) resulted in increased lipid deposition on Balafilcon A lenses compared to unoxidized lipids, but this was not observed for Senofilcon A lenses. Further oxidation of the lipids (carbon chain breakup) on the other hand resulted in diminished lipid deposition for both contact lens types. This study provides a method for inducing and controlling lipid oxidation so that the effect of lipid oxidation on contact lens binding can be compared. It could be shown that the degree of lipid oxidation has different effects on the lipid deposition on different contact lens types.

  12. Simulation Study of AC Contactor Dynamic Contacts Contact Pressure Based on ADAMS

    Directory of Open Access Journals (Sweden)

    Gu Yungao

    2015-01-01

    Full Text Available A multi-body dynamics simulation model of CJ20-25 AC contactor was established with Pro/E(Pro/Engineerin this paper. A coupling simulation with machine, electric, magnetic on the contactor has been achieved in this model. Dynamic parameters which were called use the secondary development technology of ADAMS. The dynamic contact pressure signal of an AC contactor was obtained with ADAMS’s own simultaneous solution such as electromagnetic suction, kinematics and dynamics equations. The simulation results and actual measurement of contactor contact pressure signals are very similar. However, the complexity of the measured contacts vibration is greater than the simulation results because the actual working condition is more complex. This result provides a theoretical foundation to the dynamic contacts contact pressure test.

  13. Graphene oxide based contacts as probes of biomedical signals

    Science.gov (United States)

    Hallfors, N. G.; Devarajan, A.; Farhat, I. A. H.; Abdurahman, A.; Liao, K.; Gater, D. L.; Elnaggar, M. I.; Isakovic, A. F.

    We have developed a series of graphene oxide (GOx) on polymer contacts and have demonstrated these to be useful for collection of standard biomedically relevant signals, such as electrocardiogram (ECG). The process is wet solution-based and allows for control and tuning of the basic physical parameters of GOx, such as electrical and optical properties, simply by choosing the number of GOx layers. Our GOx characterization measurements show spectral (FTIR, XPS, IR absorbance) features most relevant to such performance, and point towards the likely explanations about the mechanisms for controlling the physical properties relevant for the contact performance. Structural (X-ray topography) and surface characterization (AFM, SEM) indicates to what degree these contacts can be considered homogeneous and therefore provide information on yield and repeatability. We compare the ECG signals recorded by standard commercial probes (Ag/AgCl) and GOx probes, displaying minor differences the solution to which may lead to a whole new way we perform ECG data collection, including wearable electronics and IoT friendly ECG monitoring. We acknowledge support from Mubadala-SRC AC4ES and from SRC 2011-KJ-2190. We thank J. B. Warren and G. L. Carr (BNL) for assistance.

  14. Experimental analysis of heat and mass transfer phenomena in a direct contact evaporative cooling tower

    Energy Technology Data Exchange (ETDEWEB)

    Lemouari, M. [Department of Processes Engineering, Faculty of Sciences and Engineering, University of Bejaia (Algeria); Boumaza, M. [Department of Chemical Engineering, College of Engineering - King Saud University, P.O. Box 800, Riyadh (Saudi Arabia); Kaabi, A. [Department of Genie Climatique, Faculty of Engineering, University of Constantine, Constantine (Algeria)

    2009-06-15

    This paper deals with an experimental analysis of simultaneous heat and mass transfer phenomena between water and air by direct contact in a packed cooling tower. The tower is filled with a ''VGA.'' (Vertical Grid Apparatus) type packing. The packing is 0.42 m high and consists of four (04) galvanised sheets having a zigzag form, between which are disposed three (03) metallic vertical grids in parallel with a cross-sectional test area of 0.15 m x 0.148 m. This study investigates the effect of the air and water flow rates on the global heat and mass transfer coefficient as well as the evaporation rate of water into the air stream, for different inlet water temperatures. Two operating regimes were observed during the air/water contact inside the tower, a Pellicular Regime (PR) and a Bubble and Dispersion Regime (BDR). These two regimes can determine the best way to promote the heat and mass transfer phenomena in such device. The BDR regime seems to be more efficient than the Pellicular Regime, as it enables to achieve relatively higher values of the global heat and mass transfer coefficient and larger water evaporation rates. The comparison between the obtained results and some of those available in the literature for other types of packing indicates that this type possesses good heat and mass transfer characteristics. (author)

  15. Analytical and experimental analysis of a free link in contact with a granular medium.

    Science.gov (United States)

    Marghitu, Dan B; Lee, Seung

    2013-01-01

    In this study, the experimental and the simulation results for a planar free link impacting a granular medium are analyzed. The resistance force of the granular medium on the body from the moment of the impact until the body stops is very important. Horizontal and vertical static resistance forces developed by theoretical and empirical approaches are considered. The penetrating depth of the impacting end of the free link increases with the increase of the initial impacting velocity. We define the stopping time as the time interval from the moment of impact until the vertical velocity of the link end is zero. The stopping time of the end decreases as the initial velocity increases. The faster the end of the link impacts the surface of the granular medium, the sooner it will come to a stop. This phenomenon involves how rapidly a free link strikes the granular medium and how it slows down upon contact.

  16. Analytical and Experimental Analysis of a Free Link in Contact with a Granular Medium

    Directory of Open Access Journals (Sweden)

    Dan B. Marghitu

    2013-01-01

    Full Text Available In this study, the experimental and the simulation results for a planar free link impacting a granular medium are analyzed. The resistance force of the granular medium on the body from the moment of the impact until the body stops is very important. Horizontal and vertical static resistance forces developed by theoretical and empirical approaches are considered. The penetrating depth of the impacting end of the free link increases with the increase of the initial impacting velocity. We define the stopping time as the time interval from the moment of impact until the vertical velocity of the link end is zero. The stopping time of the end decreases as the initial velocity increases. The faster the end of the link impacts the surface of the granular medium, the sooner it will come to a stop. This phenomenon involves how rapidly a free link strikes the granular medium and how it slows down upon contact.

  17. Experimental and numerical investigations on the direct contact condensation phenomenon in horizontal flow channels and its implications in nuclear safety

    Energy Technology Data Exchange (ETDEWEB)

    Ceuca, Sabin Cristian [Gesellschaft fuer Anlagen- und Reaktorsicherheit (GRS) gGmbH, Garching (Germany); Laurinavicius, Darius [Lithuanian Energy Institute, Kaunas (Lithuania)

    2016-11-15

    The complex direct contact condensation phenomenon is investigated in horizontal flow channels both experimentally and numerically with special emphasis on its implications on safety assessment studies. Under certain conditions direct contact condensation can act as the driving force for the water hammer phenomenon with potentially local devastating results, thus posing a threat to the integrity of the affected NPP components. New experimental results of in-depth analysis of the direct contact condensation phenomena obtained in Kaunas at the Lithuanian Energy Institute will be presented. The German system code ATHLET employing for the calculation of the heat transfer coefficient a mechanistic model accounting for two different eddy length scales, combined with the interfacial area transport equation will be assessed against condensation induced water hammer experimental data from the integral thermal-hydraulic experimental facility PMK-2, located at the KFKI Atomic Energy Research Institute in Budapest Hungary.

  18. A Research Based on the metering and detecting Device for Industrial dispenser of non-contact technology

    Science.gov (United States)

    Chen, Xin; Li, Jingjing; Wang, Jingying

    2017-12-01

    Based on the non-contact detection technology, for the needs of on-site measurement for industrial dispenser, the dispenser device is designed and utilized non-contact laser measuring technology with high precision for measurement of length and speed to measure the coordination of displacement stroke and speed. According to “GBT 26799-2011 technical conditions for General Dispenser”, several key parameters are detected by comparing the experimental results, to meet the metering requirements of industrial dispenser.

  19. A damage mechanics based general purpose interface/contact element

    Science.gov (United States)

    Yan, Chengyong

    Most of the microelectronics packaging structures consist of layered substrates connected with bonding materials, such as solder or epoxy. Predicting the thermomechanical behavior of these multilayered structures is a challenging task in electronic packaging engineering. In a layered structure the most complex part is always the interfaces between the strates. Simulating the thermo-mechanical behavior of such interfaces, is the main theme of this dissertation. The most commonly used solder material, Pb-Sn alloy, has a very low melting temperature 180sp°C, so that the material demonstrates a highly viscous behavior. And, creep usually dominates the failure mechanism. Hence, the theory of viscoplasticity is adapted to describe the constitutive behavior. In a multilayered assembly each layer has a different coefficient of thermal expansion. Under thermal cycling, due to heat dissipated from circuits, interfaces and interconnects experience low cycle fatigue. Presently, the state-of-the art damage mechanics model used for fatigue life predictions is based on Kachanov (1986) continuum damage model. This model uses plastic strain as a damage criterion. Since plastic strain is a stress path dependent value, the criterion does not yield unique damage values for the same state of stress. In this dissertation a new damage evolution equation based on the second law of thermodynamic is proposed. The new criterion is based on the entropy of the system and it yields unique damage values for all stress paths to the final state of stress. In the electronics industry, there is a strong desire to develop fatigue free interconnections. The proposed interface/contact element can also simulate the behavior of the fatigue free Z-direction thin film interconnections as well as traditional layered interconnects. The proposed interface element can simulate behavior of a bonded interface or unbonded sliding interface, also called contact element. The proposed element was verified against

  20. A novel multi-stage direct contact membrane distillation module: Design, experimental and theoretical approaches.

    Science.gov (United States)

    Lee, Jung-Gil; Kim, Woo-Seung; Choi, June-Seok; Ghaffour, Noreddine; Kim, Young-Deuk

    2016-12-15

    An economic desalination system with a small scale and footprint for remote areas, which have a limited and inadequate water supply, insufficient water treatment and low infrastructure, is strongly demanded in the desalination markets. Here, a direct contact membrane distillation (DCMD) process has the simplest configuration and potentially the highest permeate flux among all of the possible MD processes. This process can also be easily instituted in a multi-stage manner for enhanced compactness, productivity, versatility and cost-effectiveness. In this study, an innovative, multi-stage, DCMD module under countercurrent-flow configuration is first designed and then investigate both theoretically and experimentally to identify its feasibility and operability for desalination application. Model predictions and measured data for mean permeate flux are compared and shown to be in good agreement. The effect of the number of module stages on the mean permeate flux, performance ratio and daily water production of the MDCMD system has been theoretically identified at inlet feed and permeate flow rates of 1.5 l/min and inlet feed and permeate temperatures of 70 °C and 25 °C, respectively. The daily water production of a three-stage DCMD module with a membrane area of 0.01 m2 at each stage is found to be 21.5 kg. Copyright © 2016 Elsevier Ltd. All rights reserved.

  1. A novel multi-stage direct contact membrane distillation module: Design, experimental and theoretical approaches

    KAUST Repository

    Lee, Jung Gil

    2016-10-24

    An economic desalination system with a small scale and footprint for remote areas, which have a limited and inadequate water supply, insufficient water treatment and low infrastructure, is strongly demanded in the desalination markets. Here, a direct contact membrane distillation (DCMD) process has the simplest configuration and potentially the highest permeate flux among all of the possible MD processes. This process can also be easily instituted in a multi-stage manner for enhanced compactness, productivity, versatility and cost-effectiveness. In this study, an innovative, multi-stage, DCMD module under countercurrent-flow configuration is first designed and then investigate both theoretically and experimentally to identify its feasibility and operability for desalination application. Model predictions and measured data for mean permeate flux are compared and shown to be in good agreement. The effect of the number of module stages on the mean permeate flux, performance ratio and daily water production of the MDCMD system has been theoretically identified at inlet feed and permeate flow rates of 1.5 l/min and inlet feed and permeate temperatures of 70 °C and 25 °C, respectively. The daily water production of a three-stage DCMD module with a membrane area of 0.01 m2 at each stage is found to be 21.5 kg.

  2. Migration by 'direct' or 'indirect' food contact? 'Dry' and 'wetting' foods? Experimental data for 'touching' contact of dry foods with paper and board.

    Science.gov (United States)

    Eicher, Angela; Biedermann, Maurus; Zurfluh, Michael; Grob, Koni

    2015-01-01

    Food contact is characterised in various terms, all of which are somewhat ill-defined. This work investigated the simplification that migration from food contact materials into dry food virtually exclusively proceeds through the gas phase, which would imply that the migration of essentially non-volatile components is negligible. It is shown here that this is not necessarily appropriate: for newspaper printed with an ink based on essentially non-volatile polyalphaolefins (PAO) as the main solvent, the migration into polenta and a baking mix reached 64% and 66% respectively of the content in the paper in merely 20 days at ambient temperature. Migration of involatile substances into dry foods implies diffusion through the paper to the small contact points. It depended on particle size, as this determines the density of the contacts. The diffusion rates within the food contact material and the food, including the transfer from one particle to the next, are other determining factors. This leaves the question whether such migration can be modelled or tested in a systematic manner (simulation), or whether it needs to be determined on a case-by-case basis.

  3. PSD Camera Based Position and Posture Control of Redundant Robot Considering Contact Motion

    Science.gov (United States)

    Oda, Naoki; Kotani, Kentaro

    The paper describes a position and posture controller design based on the absolute position by external PSD vision sensor for redundant robot manipulator. The redundancy enables a potential capability to avoid obstacle while continuing given end-effector jobs under contact with middle link of manipulator. Under contact motion, the deformation due to joint torsion obtained by comparing internal and external position sensor, is actively suppressed by internal/external position hybrid controller. The selection matrix of hybrid loop is given by the function of the deformation. And the detected deformation is also utilized in the compliant motion controller for passive obstacle avoidance. The validity of the proposed method is verified by several experimental results of 3link planar redundant manipulator.

  4. Mass spectrometry-based proteomic analyses of contact lens deposition.

    Science.gov (United States)

    Green-Church, Kari B; Nichols, Jason J

    2008-02-08

    The purpose of this report is to describe the contact lens deposition proteome associated with two silicone hydrogel contact lenses and care solutions using a mass spectrometric-based approach. This was a randomized, controlled, examiner-masked crossover clinical trial that included 48 participants. Lenses and no-rub care solutions evaluated included galyfilcon A (Acuvue Advance, Vistakon Inc., Jacksonville, FL), lotrafilcon B (O2 Optix, CIBA Vision Inc., Duluth, GA), AQuify (CIBA Vision Inc.), and ReNu MoistureLoc (Bausch and Lomb Inc., Rochester, NY). After two weeks of daily wear in each lens-solution combination, the left lens was removed by the examiner (using gloves and forceps) and placed in a protein precipitation buffer (acetone). The precipitate was quantitated for total protein concentration (per lens), and proteins were then identified using liquid chromatography tandem mass spectrometry (nano-LC-MS/MS) and peptide sequencing. Between 7.32 and 9.76 microg/lens of protein was observed on average from each lens-solution combination. There were 19 total unique proteins identified across the two lens materials, and six proteins were identified in all four lens-solution combinations including lipocalin, lysozyme, lacritin, lactoferrin, proline rich 4, and Ig Alpha. Lotrafilcon B was associated with 15 individual proteins (across both care solutions), and 53% of these proteins were observed in at least 50% of the analyses. Galyfilcon A was associated with 13 individual proteins, and 38.5% of these proteins were observed in at least 50% of the analyses. There were three unique proteins identified from galyfilcon A and four unique proteins identified from lotrafilcon B. The total amount of proteins identified from silicone hydrogel materials is much less than the amount from traditional soft lens materials. For the most part, the deposition proteome across these lenses is similar, although the different polymer characteristics might be associated with some

  5. Contact in the Classroom: Developing a Program Model for Youth Mental Health Contact-Based Anti-stigma Education.

    Science.gov (United States)

    Chen, Shu-Ping; Koller, Michelle; Krupa, Terry; Stuart, Heather

    2016-04-01

    This study evaluated eighteen Canadian anti-stigma programs targeting high-school students. The purpose was to identify critical domains and develop a program model of contact-based interventions. Three steps were implemented. The first step involved collecting program information through twenty in-depth interviews with stakeholders and field observations of seven programs. The second step involved constructing critical ingredients into domains for conceptual clarity and component modeling. The third step involved validating the program model by stakeholders review and initial fidelity testing with program outcomes. A program model with an overarching theme "engaging contact reduces stigma" and three underlying constructs (speakers, message, and interaction) were developed. Within each construct three specific domains were identified to explain the concepts. Connection, engagement, and empowerment are critical domains of anti-stigma programs for the youth population. Findings from this study have built on the scientific knowledge about the change theory underpinning youth contact-based intervention.

  6. Ni-Based Ohmic Contacts to n-Type 4H-SiC: The Formation Mechanism and Thermal Stability

    Directory of Open Access Journals (Sweden)

    A. V. Kuchuk

    2016-01-01

    Full Text Available The fabrication of low-resistance and thermal stable ohmic contacts is important for realization of reliable SiC devices. For the n-type SiC, Ni-based metallization is most commonly used for Schottky and ohmic contacts. Many experimental studies have been performed in order to understand the mechanism of ohmic contact formation and different models were proposed to explain the Schottky to ohmic transition for Ni/SiC contacts. In the present review, we summarize the last key results on the matter and post open questions concerning the unclear issues of ohmic contacts to n-type SiC. Analysis of the literature data and our own experimental observations have led to the conclusion that the annealing at high temperature leads to the preferential orientation of silicide at the heterointerface (0001SiC//(013δ-Ni2Si. Moreover, we may conclude that only δ-Ni2Si grains play a key role in determining electrical transport properties at the contact/SiC interface. Finally, we show that the diffusion barriers with free diffusion path microstructure can improve thermal stability of metal-SiC ohmic contacts for high-temperature electronics.

  7. Contamination without contact : An examination of intention-based contagion

    NARCIS (Netherlands)

    Stavrova, O.; Newman, George; Kulemann, Anna; Fetchenhauer, Detlef

    Contagion refers to the belief that individuals or objects can acquire the essence of a particular source, such as a disgusting product or an immoral person, through physical contact. This paper documents beliefs in a "contact-free" form of contagion whereby an object is thought to inherit the

  8. Improved DDA Method Based on Explicitly Solving Contact Constraints

    National Research Council Canada - National Science Library

    Zhao, Jian; Xiao, Ming; Chen, Juntao; Li, Dongdong

    2016-01-01

    ... for discontinuous rock mass. The DDA method can efficiently simulate mutual contact between blocks, account for the impact of geological joints on block movement, and calculate the displacement and deformation...

  9. Rolling contact fatigue testing of peek based composites

    Directory of Open Access Journals (Sweden)

    Petrogalli C.

    2010-06-01

    Full Text Available Rolling contact fatigue phenomenon was investigated on unfilled PEEK and on three different PEEK composites: 10% carbon micro-fiber, graphite and PTFE filled matrix, 30% carbon micro-fiber filled matrix, 30% glass micro-fiber filled matrix. For this aim, roller-shaped specimens were machined from extruded bars of these materials and subjected to rolling contact tests at different contact pressure levels by means of a four roller machine. Contact pressure-life diagrams and wear rates were so obtained and compared, highlighting a relationship with monotonic and hardness materials properties. Microscopic observations of contact surfaces and transversal section of the specimens also allowed observing the damage mechanisms occurred in the materials tested and the effects of the filler. In particular way, deep radial cracks appeared on unfilled PEEK, while spalling and delamination phenomena where found on composites. Diffuse microcracks were found at the filler-matrix interface of the composites specimens, confirming that the fatigue life of these materials is essentially determined by the crack propagation phase, also under rolling contact loading.

  10. A pairwise residue contact area-based mean force potential for discrimination of native protein structure

    Directory of Open Access Journals (Sweden)

    Pezeshk Hamid

    2010-01-01

    Full Text Available Abstract Background Considering energy function to detect a correct protein fold from incorrect ones is very important for protein structure prediction and protein folding. Knowledge-based mean force potentials are certainly the most popular type of interaction function for protein threading. They are derived from statistical analyses of interacting groups in experimentally determined protein structures. These potentials are developed at the atom or the amino acid level. Based on orientation dependent contact area, a new type of knowledge-based mean force potential has been developed. Results We developed a new approach to calculate a knowledge-based potential of mean-force, using pairwise residue contact area. To test the performance of our approach, we performed it on several decoy sets to measure its ability to discriminate native structure from decoys. This potential has been able to distinguish native structures from the decoys in the most cases. Further, the calculated Z-scores were quite high for all protein datasets. Conclusions This knowledge-based potential of mean force can be used in protein structure prediction, fold recognition, comparative modelling and molecular recognition. The program is available at http://www.bioinf.cs.ipm.ac.ir/softwares/surfield

  11. Non-contact versus contact-based sensing methodologies for in-home upper arm robotic rehabilitation.

    Science.gov (United States)

    Howard, Ayanna; Brooks, Douglas; Brown, Edward; Gebregiorgis, Adey; Chen, Yu-Ping

    2013-06-01

    In recent years, robot-assisted rehabilitation has gained momentum as a viable means for improving outcomes for therapeutic interventions. Such therapy experiences allow controlled and repeatable trials and quantitative evaluation of mobility metrics. Typically though these robotic devices have been focused on rehabilitation within a clinical setting. In these traditional robot-assisted rehabilitation studies, participants are required to perform goal-directed movements with the robot during a therapy session. This requires physical contact between the participant and the robot to enable precise control of the task, as well as a means to collect relevant performance data. On the other hand, non-contact means of robot interaction can provide a safe methodology for extracting the control data needed for in-home rehabilitation. As such, in this paper we discuss a contact and non-contact based method for upper-arm rehabilitation exercises that enables quantification of upper-arm movements. We evaluate our methodology on upper-arm abduction/adduction movements and discuss the advantages and limitations of each approach as applied to an in-home rehabilitation scenario.

  12. Inferring a district-based hierarchical structure of social contacts from census data.

    Science.gov (United States)

    Yu, Z; Liu, J; Zhu, X

    2015-01-01

    Researchers have recently paid attention to social contact patterns among individuals due to their useful applications in such areas as epidemic evaluation and control, public health decisions, chronic disease research and social network research. Although some studies have estimated social contact patterns from social networks and surveys, few have considered how to infer the hierarchical structure of social contacts directly from census data. In this paper, we focus on inferring an individual's social contact patterns from detailed census data, and generate various types of social contact patterns such as hierarchical-district-structure-based, cross-district and age-district-based patterns. We evaluate newly generated contact patterns derived from detailed 2011 Hong Kong census data by incorporating them into a model and simulation of the 2009 Hong Kong H1N1 epidemic. We then compare the newly generated social contact patterns with the mixing patterns that are often used in the literature, and draw the following conclusions. First, the generation of social contact patterns based on a hierarchical district structure allows for simulations at different district levels. Second, the newly generated social contact patterns reflect individuals social contacts. Third, the newly generated social contact patterns improve the accuracy of the SEIR-based epidemic model.

  13. Experimental use of semiconductor diode laser in contact transscleral cyclophotocoagulation in rabbits.

    Science.gov (United States)

    Schuman, J S; Jacobson, J J; Puliafito, C A; Noecker, R J; Reidy, W T

    1990-08-01

    Acute and long-term effects of contact transscleral semiconductor diode laser cyclophotocoagulation were studied in rabbits. Immediately following cyclophotocoagulation, light microscopy revealed coagulation necrosis of the ciliary pigmented and nonpigmented epithelia and stroma; destruction increased in relation to power. There was architectural disruption with higher energy levels. The findings with diode and continuous-wave contact neodymium-YAG lasers were similar. In rabbits treated and followed up for 6 weeks there was a decrease in intraocular pressure during the observation period (P less than .05, paired Student's t test). The gross and light microscopic examination revealed focal atrophy and fibrosis of the ciliary processes, with pigment-laden macrophages on the ciliary processes and in the outflow pathways. Higher energy levels caused lens capsule damage and vitritis. The diode laser produced ciliary destruction similar to the continuous-wave contact neodymium-YAG laser in rabbits, with significant intraocular pressure lowering during the 6-week follow-up.

  14. an architecture-based technique to mobile contact recommendation

    African Journals Online (AJOL)

    user

    Facebook, YouTube(and other social media platforms) on the fly [3]. It is interesting to note that all mobile phones are not smartphones. But, they all have the same ability to store the names and phone number(s) of. Relatives, Friends or other Close Acquaintance (RFoCA). Aside being able to store the name of contacts and ...

  15. Cantilever based mass sensor with hard contact readout

    DEFF Research Database (Denmark)

    Dohn, Søren; Hansen, Ole; Boisen, Anja

    2006-01-01

    We present a method for microcantilever resonant frequency detection. We measure the direct current from an intermittent contact once every vibration cycle between the conducting cantilever and a counterelectrode at a low bias voltage with respect to the cantilever, while the excitation frequency...

  16. Alternative current source based Schottky contact with additional electric field

    Science.gov (United States)

    Mamedov, R. K.; Aslanova, A. R.

    2017-07-01

    Additional electric field (AEF) in the Schottky contacts (SC) that covered the peripheral contact region wide and the complete contact region narrow (as TMBS diode) SC. Under the influence of AEF is a redistribution of free electrons produced at certain temperatures of the semiconductor, and is formed the space charge region (SCR). As a result of the superposition of the electric fields SCR and AEF occurs the resulting electric field (REF). The REF is distributed along a straight line perpendicular to the contact surface, so that its intensity (and potential) has a minimum value on the metal surface and the maximum value at a great distance from the metal surface deep into the SCR. Under the influence of AEF as a sided force the metal becomes negative pole and semiconductor - positive pole, therefore, SC with AEF becomes an alternative current source (ACS). The Ni-nSi SC with different diameters (20-1000 μm) under the influence of the AEF as sided force have become ACS with electromotive force in the order of 0.1-1.0 mV, which are generated the electric current in the range of 10-9-10-7 A, flowing through the external resistance 1000 Ohm.

  17. An elastography method based on the scanning contact resonance of a piezoelectric cantilever.

    Science.gov (United States)

    Fu, Ji; Li, Faxin

    2013-12-01

    Most tissues may become significantly stiffer than their normal states when there are lesions inside. The tissue's modulus can then act as an identification parameter for clinic diagnosis of tumors or fibrosis, which leads to elastography. This study introduces a novel elastography method that can be used for modulus imaging of superficial organs. This method is based on the scanning contact-resonance of a unimorph piezoelectric cantilever. The cantilever vibrates in its bending mode with the tip pressed tightly on the sample. The contact resonance frequency of the cantilever-sample system is tracked at each scanning point, from which the sample's modulus can be derived based on a beam dynamic model and a contact mechanics model. Scanning is performed by a three-dimensional motorized stage and the whole system is controlled by a homemade software program based on LabVIEW. Testing on in vitro beef tissues indicates that the fat and the muscle can be easily distinguished using this system, and the accuracy of the modulus measurement can be comparable with that of nanoindentation. Imaging on homemade gelatin phantoms shows that the depth information of the abnormalities can be qualitatively obtained by varying the pressing force. The detection limit of this elastography method is specially examined both experimentally and numerically. Results show that it can detect the typical lesions in superficial organs with the depth of several centimeters. The lateral resolution of this elastography method∕system is better than 0.5 mm, and could be further enhanced by using more scanning points. The proposed elastography system can be regarded as a sensitive palpation robot, which may be very promising in early diagnosis of tumors in superficial organs such as breast and thyroid.

  18. An elastography method based on the scanning contact resonance of a piezoelectric cantilever

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Ji; Li, Faxin, E-mail: lifaxin@pku.edu.cn [State Key Lab for Turbulence and Complex Systems, College of Engineering, Peking University, Beijing 100871, China and HEDPS, Center for Applied Physics and Technologies, Peking University, Beijing 100871 (China)

    2013-12-15

    Purpose: Most tissues may become significantly stiffer than their normal states when there are lesions inside. The tissue's modulus can then act as an identification parameter for clinic diagnosis of tumors or fibrosis, which leads to elastography. This study introduces a novel elastography method that can be used for modulus imaging of superficial organs. Methods: This method is based on the scanning contact-resonance of a unimorph piezoelectric cantilever. The cantilever vibrates in its bending mode with the tip pressed tightly on the sample. The contact resonance frequency of the cantilever-sample system is tracked at each scanning point, from which the sample's modulus can be derived based on a beam dynamic model and a contact mechanics model. Scanning is performed by a three-dimensional motorized stage and the whole system is controlled by a homemade software program based on LabVIEW. Results: Testing onin vitro beef tissues indicates that the fat and the muscle can be easily distinguished using this system, and the accuracy of the modulus measurement can be comparable with that of nanoindentation. Imaging on homemade gelatin phantoms shows that the depth information of the abnormalities can be qualitatively obtained by varying the pressing force. The detection limit of this elastography method is specially examined both experimentally and numerically. Results show that it can detect the typical lesions in superficial organs with the depth of several centimeters. The lateral resolution of this elastography method/system is better than 0.5 mm, and could be further enhanced by using more scanning points. Conclusions: The proposed elastography system can be regarded as a sensitive palpation robot, which may be very promising in early diagnosis of tumors in superficial organs such as breast and thyroid.

  19. Transport phenomena and fouling in vacuum enhanced direct contact membrane distillation: Experimental and modelling

    KAUST Repository

    Naidu, Gayathri

    2016-08-27

    The application of vacuum to direct contact membrane distillation (vacuum enhanced direct contact membrane distillation, V-DCMD) removed condensable gasses and reduced partial pressure in the membrane pores, achieving 37.6% higher flux than DCMD at the same feed temperature. Transfer mechanism and temperature distribution profile in V-DCMD were studied. The empirical flux decline (EFD) model represented fouling profiles of V-DCMD. In a continuous V-DCMD operation with moderate temperature (55 degrees C) and permeate pressure (300 mbar) for treating wastewater ROC, a flux of 16.0 +/- 0.3 L/m(2) h and high quality distillate were achieved with water flushing, showing the suitability of V-DCMD for ROC treatment. (C) 2016 Elsevier B.V. All rights reserved.

  20. Experimental Analysis of Displacements and Shears at the Surface on Contact between Two Loaded Bodies,

    Science.gov (United States)

    1980-07-01

    structures. The method is applied in an Investigation of one forn of behavior of buoy-cable systems loaded by the action of surface waves. 27. A. J...strain pages, dial vapes and micrometers are used to determine the stress distri- bution In a belt-pulley gymtem. Contact and tangential stress for...materials used in the tests deformed appreciably, but the mechanical behavior was linear within the range of the deformations imposed. Poisson’s ratio

  1. Effects of Experimental Volleyball Rules Quantified by Type and Number of Jumps, Hits and Contacts

    Directory of Open Access Journals (Sweden)

    Mladen Stankovic

    2017-10-01

    Full Text Available The purpose of this study was to determine the influence of the two new rules tested at the inaugural U23 Men’s Volleyball World Championship (21-point set excluding the fifth set, and 15 seconds between rallies–10 seconds from the finished point until the referee’s whistle for serve and five seconds for performing the serve on number and types of jumps and number of contacts and hits. The analysis comprised 25,930 jumps (an essential physical activity for volleyball, 15,706 contacts and 10,224 hits during 36 matches played by 144 males aged under 23 at the first Under 23 Men’s World Championships organized in Uberlandia, Brazil, in 2013. Two investigations were conducted: 1 Analysis of jumps by Jump type, In-game role and Level of set win; 2 Analysis of contacts (reception, setting, block, defense and hits (serve and attack by Type, In-game role and Set outcome. Significant differences (p=0.000 were found between in-game role and jump type, as Middle blocker performed the most (34.7%, followed by Outside hitter (24.9%, Setter (24.6% and Opposite (15.8%. Significant differences were found for number and types of Hits between set Winner and Loser teams only for serves by Setter (p<0.001 and Middle blocker (p<0.05. The results showed major differences in jumps, hits and contacts between in-game roles: Middle blocker was the most frequent jumping position, followed by Outside hitter and Setter. The Libero showed a new tendency of being Setter with a jump after the initial Setter defense.

  2. Experimental Study on the Dynamic Performance of Water-Lubricated Rubber Bearings with Local Contact

    Directory of Open Access Journals (Sweden)

    Wu Ouyang

    2018-01-01

    Full Text Available Accurate dynamic characteristic coefficients of water-lubricated rubber bearings are necessary to research vibration of ship propulsion system. Due to mixed lubrication state of water-lubricated rubber bearings, normal test rig and identification method are not applicable. This paper establishes a test rig to simulate shaft misalignment and proposes an identification method for water-lubricated rubber bearings, which utilizes rotor unbalanced motion to produce self-excited force rather than artificial excitation. Dynamic performance tests under different conditions are operated. The results show that when rotational speed is less than 700 r/min, even if specific pressure is 0.05 MPa, it is difficult to form complete water film for the rubber bearing which was investigated, and contact friction and collision of the shaft and bearing are frequent. In the mixed lubrication, water film, rubber, and contact jointly determine dynamic characteristics of water-lubricated rubber bearings. The contact condition has a significant effect on the bearing stiffness, and water film friction damping has a significant effect on bearing damping. As for the particular investigated bearing, when rotational speed is in the range of 400~700 r/min and specific pressure is in the range of 0.03~0.07 MPa, bearing stiffness is in the range of 5.6~10.06 N/μm and bearing damping is in the range of 1.25~2.02 Ns/μm.

  3. Experimental Evaluation of Faecal Escherichia coli and Hepatitis E Virus as Biological Indicators of Contacts Between Domestic Pigs and Eurasian Wild Boar.

    Science.gov (United States)

    Barth, S; Geue, L; Hinsching, A; Jenckel, M; Schlosser, J; Eiden, M; Pietschmann, J; Menge, C; Beer, M; Groschup, M; Jori, F; Etter, E; Blome, S

    2017-04-01

    Domestic pigs and Eurasian wild boar (Sus scrofa) share several important viral and bacterial pathogens. Therefore, direct and indirect contacts between domestic pigs and wild boar present a risk of pathogen spillover and can lead to long-term perpetuation of infection. Biological indicators could be a powerful tool to understand and characterize contacts between wild boar and domestic pigs. Here, faecal Escherichia coli and Hepatitis E virus (HEV) were explored as potential biological indicators under experimental conditions. The data gained in our pilot study suggest that faecal E. coli can be used as biological indicator of contact between wild boar and domestic pig. For HEV, faecal transmission was also confirmed. However, molecular studies on full-genome basis did not reveal markers that would allow tracing of transmission direction. Based on these promising results, future field studies will especially target the practicability of E. coli microbiome molecular typing as surrogate of contacts at the wildlife-livestock interface. © 2015 Blackwell Verlag GmbH.

  4. Mechanisms for Strong Anisotropy of In-Plane g -Factors in Hole Based Quantum Point Contacts

    Science.gov (United States)

    Miserev, D. S.; Srinivasan, A.; Tkachenko, O. A.; Tkachenko, V. A.; Farrer, I.; Ritchie, D. A.; Hamilton, A. R.; Sushkov, O. P.

    2017-09-01

    In-plane hole g factors measured in quantum point contacts based on p -type heterostructures strongly depend on the orientation of the magnetic field with respect to the electric current. This effect, first reported a decade ago and confirmed in a number of publications, has remained an open problem. In this work, we present systematic experimental studies to disentangle different mechanisms contributing to the effect and develop the theory which describes it successfully. We show that there is a new mechanism for the anisotropy related to the existence of an additional B+k-4σ+ effective Zeeman interaction for holes, which is kinematically different from the standard single Zeeman term B-k-2σ+ considered until now.

  5. Diagnosis of Constant Faults in Read-Once Contact Networks over Finite Bases using Decision Trees

    KAUST Repository

    Busbait, Monther I.

    2014-05-01

    We study the depth of decision trees for diagnosis of constant faults in read-once contact networks over finite bases. This includes diagnosis of 0-1 faults, 0 faults and 1 faults. For any finite basis, we prove a linear upper bound on the minimum depth of decision tree for diagnosis of constant faults depending on the number of edges in a contact network over that basis. Also, we obtain asymptotic bounds on the depth of decision trees for diagnosis of each type of constant faults depending on the number of edges in contact networks in the worst case per basis. We study the set of indecomposable contact networks with up to 10 edges and obtain sharp coefficients for the linear upper bound for diagnosis of constant faults in contact networks over bases of these indecomposable contact networks. We use a set of algorithms, including one that we create, to obtain the sharp coefficients.

  6. An experimental and computational study of size-dependent contact-angle of dewetted metal nanodroplets below its melting temperature

    Science.gov (United States)

    Azeredo, Bruno P.; Yeratapally, Saikumar R.; Kacher, Josh; Ferreira, Placid M.; Sangid, Michael D.

    2016-11-01

    Decorating 1D nanostructures (e.g., wires and tubes) with metal nanoparticles serves as a hierarchical approach to integrate the functionalities of metal oxides, semiconductors, and metals. This paper examines a simple and low-temperature approach to self-assembling gold nanoparticles (Au-np)—a common catalytic material—onto silicon nanowires (SiNWs). A conformal ultra-thin film (i.e., temperature profile has a strong effect on the particle size. Additionally, the contact angle is found to be dependent on particle size and temperature even below the eutectic temperature of the Au-Si alloy. Molecular dynamics simulations were performed to investigate potential explanations for such experimental observation. In this temperature regime, the simulations reveal the formation of an amorphous phase at the interface between the catalyst and SiNW that is sensitive to temperature. This amorphous layer increases the adhesion energy at the interface and explains the contact angle dependence on temperature.

  7. Experimental assesment of up-dosing with bilastine on clinical effectiveness in cold contact urticaria

    OpenAIRE

    Spohr, Adrian

    2014-01-01

    Background: Cold contact urticaria (CCU) is characterized by itchy wheal and flare responses due to the release of histamine and other pro-inflammatory mediators after exposure to cold. The treatment of choice in CCU are non-sedating H1 antihistamines. If patients cannot be sufficiently controlled with standard dosages, the current EAACI/GA2LEN/EDF/WAO-guideline for the management of urticaria recommends high-dose H1 blockers up to 4 times the standard dose. Objective: Aim of the study is...

  8. Contact allergy to colophony. Clinical and experimental studies with emphasis on clinical relevance.

    Science.gov (United States)

    Färm, G

    1998-01-01

    Colophony--also called rosin--is a material obtained from coniferous trees. It is used widely in many products, particularly because of its good tackifying properties. Colophony is also used in paper sizing to increase water resistance. Colophony may cause contact allergy, and around 5% of Swedish dermatitis patients show allergic reactions to colophony at patch testing. There are many case reports of colophony in different products causing contact dermatitis. Often, however, the clinical relevance of a positive patch-test reaction to colophony is difficult to evaluate. The principal aims of the present thesis were to study the prevalence of contact allergy to colophony and of skin disease in individuals with an occupational exposure to colophony; to study the prognosis of dermatitis in colophony-sensitive subjects, and to investigate the outcome of repeated open applications of colophony, thereby trying to elucidate the clinical relevance of contact allergy to colophony. Employees of a tall-oil rosin (colophony) factory (n = 180), and of an opera company where colophony was used in dancers' rosin, mascara and wig glues (n = 132), were interviewed, examined and patch tested. 3.9% and 2% of these two groups respectively had a positive patch test to colophony. More than every fourth participant showed some kind of skin disease, but only few cases were related to work. Eighty-three patients with previously diagnosed contact allergy to colophony were followed-up 72% showed a positive patch-test reaction to colophony at re-testing. Around one third had hand eczema. There was no significant correlation between colophony exposure and current hand eczema. Adhesive bandages containing colophony and zinc oxide (ZnO), colophony and mixes of colophony and ZnO, were tested in 7 colophony-sensitive subjects to see whether addition of zinc oxide inhibited elicitation of allergic dermatitis to colophony, which has been proposed. No difference in reactivity between colophony and

  9. NANOCOMPOSITE POWDERS FOR NEW CONTACT MATERIALS BASED ONCOPPER AND ALUMINA

    Directory of Open Access Journals (Sweden)

    Marija Korać

    2008-11-01

    Full Text Available This paper is a contribution to characterization of Cu-Al2O3 powders with nanostructure designed for the production of dispersion strengthened contact materials. New materials with predetermined properties can be successfully synthesized by utilizing the principles of hydrometallurgy and powder metallurgy. The results show a development of a new procedure for the synthesis. The applied characterization methods were differential thermal and thermogravimetric analysis (DTA-TGA, X-ray diffraction (XRD, scanning electron microscopy (SEM, Transmission Electron Microscopy (TEM: Focused Ion Beam (FIB and Analytical Electron Microscopy (AEM. Nanostructure characteristics, particle size in range 20-50 nm, and uniform distribution of dispersoide in copper matrix were validated.

  10. Electroplated contacts and porous silicon for silicon based solar cells applications

    Energy Technology Data Exchange (ETDEWEB)

    Kholostov, Konstantin, E-mail: kholostov@diet.uniroma1.it [Department of information engineering, electronics and telecommunications, University of Rome “La Sapienza”, Via Eudossiana 18, 00184 Rome (Italy); Serenelli, Luca; Izzi, Massimo; Tucci, Mario [Enea Casaccia Research Centre Rome, via Anguillarese 301, 00123 Rome (Italy); Balucani, Marco [Department of information engineering, electronics and telecommunications, University of Rome “La Sapienza”, Via Eudossiana 18, 00184 Rome (Italy); Rise Technology S.r.l., Lungomare Paolo Toscanelli 170, 00121 Rome (Italy)

    2015-04-15

    Highlights: • Uniformity of the Ni–Si interface is crucial for performance of Cu–Ni contacts on Si. • Uniformly filled PS is the key to obtain the best performance of Cu–Ni contacts on Si. • Optimization of anodization and electroplating allows complete filling of PS layer. • Highly adhesive and low contact resistance Cu–Ni contacts are obtained on Si. - Abstract: In this paper, a two-layer metallization for silicon based solar cells is presented. The metallization consists of thin nickel barrier and thick copper conductive layers, both obtained by electrodeposition technique suitable for phosphorus-doped 70–90 Ω/sq solar cell emitter formed on p-type silicon substrate. To ensure the adhesion between metal contact and emitter a very thin layer of mesoporous silicon is introduced on the emitter surface before metal deposition. This approach allows metal anchoring inside pores and improves silicon–nickel interface uniformity. Optimization of metal contact parameters is achieved varying the anodization and electrodeposition conditions. Characterization of contacts between metal and emitter is carried out by scanning electron microscopy, specific contact resistance and current–voltage measurements. Mechanical strength of nickel–copper contacts is evaluated by the peel test. Adhesion strength of more than 4.5 N/mm and contact resistance of 350 μΩ cm{sup 2} on 80 Ω/sq emitter are achieved.

  11. Analysis of direct contact membrane distillation based on a lumped-parameter dynamic predictive model

    KAUST Repository

    Karam, Ayman M.

    2016-10-03

    Membrane distillation (MD) is an emerging technology that has a great potential for sustainable water desalination. In order to pave the way for successful commercialization of MD-based water desalination techniques, adequate and accurate dynamical models of the process are essential. This paper presents the predictive capabilities of a lumped-parameter dynamic model for direct contact membrane distillation (DCMD) and discusses the results under wide range of steady-state and dynamic conditions. Unlike previous studies, the proposed model captures the time response of the spacial temperature distribution along the flow direction. It also directly solves for the local temperatures at the membrane interfaces, which allows to accurately model and calculate local flux values along with other intrinsic variables of great influence on the process, like the temperature polarization coefficient (TPC). The proposed model is based on energy and mass conservation principles and analogy between thermal and electrical systems. Experimental data was collected to validated the steady-state and dynamic responses of the model. The obtained results shows great agreement with the experimental data. The paper discusses the results of several simulations under various conditions to optimize the DCMD process efficiency and analyze its response. This demonstrates some potential applications of the proposed model to carry out scale up and design studies. © 2016

  12. Inequity Aversion Negatively Affects Tolerance and Contact-Seeking Behaviours towards Partner and Experimenter.

    Directory of Open Access Journals (Sweden)

    Désirée Brucks

    Full Text Available Inequity aversion has been proposed to act as a limiting factor for cooperation, thus preventing subjects from disadvantageous cooperative interactions. While a recent study revealed that also dogs show some sensitivity to inequity, the underlying mechanisms of this behaviour are still unclear. The aim of the current study was threefold: 1 to replicate the study by Range et al. (2009, PNAS, 106, 340-345; 2 to investigate the emotional mechanisms involved in the inequity response by measuring the heart rate and 3 to explore the link between inequity aversion and cooperation in terms of behaviours shown towards the partner dog and towards the experimenter who caused the inequity. Dog tested in dyads were alternately asked to give their paw and were either equally or unequally rewarded by the experimenter. After each social test condition, we conducted food tolerance tests and free interaction tests in which the subjects' social behaviour towards the partner and the experimenter were observed. As in the previous study, subjects refused to continue giving their paw when only the partner was rewarded, but not when both dogs were rewarded with rewards of different quality. Although subjects did not react to this quality inequity during the test, we did find reduced durations of food sharing in the subsequent tolerance test, indicating that dogs perceived the inequity but were not able to react to it in the test context. Moreover, subjects avoided their partner and the experimenter more during the free interaction time following unequal compared to equal treatment. Despite the clear behavioural reactions to inequity, we could not detect any changes in heart rate. Results suggest that inequity aversion might in fact be mediated by simple emotional mechanisms: sharing a negative experience, like inequity, might reduce future cooperation by decreasing the likelihood of proximity being maintained between partners.

  13. Prediction of static friction coefficient in rough contacts based on the junction growth theory

    Science.gov (United States)

    Spinu, S.; Cerlinca, D.

    2017-08-01

    The classic approach to the slip-stick contact is based on the framework advanced by Mindlin, in which localized slip occurs on the contact area when the local shear traction exceeds the product between the local pressure and the static friction coefficient. This assumption may be too conservative in the case of high tractions arising at the asperities tips in the contact of rough surfaces, because the shear traction may be allowed to exceed the shear strength of the softer material. Consequently, the classic frictional contact model is modified in this paper so that gross sliding occurs when the junctions formed between all contacting asperities are independently sheared. In this framework, when the contact tractions, normal and shear, exceed the hardness of the softer material on the entire contact area, the material of the asperities yields and the junction growth process ends in all contact regions, leading to gross sliding inception. This friction mechanism is implemented in a previously proposed numerical model for the Cattaneo-Mindlin slip-stick contact problem, which is modified to accommodate the junction growth theory. The frictionless normal contact problem is solved first, then the tangential force is gradually increased, until gross sliding inception. The contact problems in the normal and in the tangential direction are successively solved, until one is stabilized in relation to the other. The maximum tangential force leading to a non-vanishing stick area is the static friction force that can be sustained by the rough contact. The static friction coefficient is eventually derived as the ratio between the latter friction force and the normal force.

  14. Field emission device driven by self-powered contact-electrification: Simulation and experimental analysis

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Xiangyu, E-mail: chenxiangyu@binn.cas.cn, E-mail: ouyangwei@phy.ecnu.edu.cn; Jiang, Tao [Beijing Institute of Nanoenergy and Nanosystems, Chinese Academy of Sciences, Beijing 100083 (China); Sun, Zhuo; Ou-Yang, Wei, E-mail: chenxiangyu@binn.cas.cn, E-mail: ouyangwei@phy.ecnu.edu.cn [Engineering Research Center for Nanophotonics and Advanced Instrument, Ministry of Education, Department of Physics, East China Normal University, 3663 North Zhongshan Road, Shanghai 200062 (China)

    2015-09-14

    A self-powered field emission device (FED) driven by a single-electrode tribo-electric nanogenerator (TENG) is demonstrated. The mechanical motion works as both a power supply to drive the FED and a control unit to regulate the amount of emitted electrons. By using the Fowler-Nordheim equation and Kirchhoff laws, a theoretical model of this self-powered FED is proposed, and accordingly the real-time output characteristics of the device are systematically investigated. It is found that the motion distance of the TENG controls switch-on of the FED and determines the charge amount for emission, while the motion velocity regulates the amplitude of emission current. The minimum contact area for the TENG to generate field emission is about 9 cm{sup 2}, which can be improved by optimizing FED structure and the tribo-materials of TENG. The demonstrated concept of this self-powered FED as well as the proposed physical analysis can serve as guidance for further applications of FED in such fields of self-powered electronics and soft electronics.

  15. Comparison of predicted and experimental thermal performance of angular-contact ball bearings

    Science.gov (United States)

    Parker, R. J.

    1984-01-01

    Predicted bearing heat generation and bearing temperature were verified by experimental data for ball bearings over a range of sizes, shaft speeds, and lubricant flow rates. The computer program Shaberth requires, as input, a factor which describes the air-oil mixture in the bearing cavity for calculation of the ball drag contribution to bearing heat generation. An equation for this lubricant percent volume in the bearing cavity was derived and appears to be valid over the range of test conditions including bearing bore sizes from 35 to 167 mm and shaft speeds from 1.0 to 3.0 million DN.

  16. Optimization of Contact Force and Pull-in Voltage for Series based MEMS Switch

    Directory of Open Access Journals (Sweden)

    Abhijeet KSHIRSAGAR

    2010-04-01

    Full Text Available Cantilever based metal-to-metal contact type MEMS series switch has many applications namely in RF MEMS, Power MEMS etc. A typical MEMS switch consists of a cantilever as actuating element to make the contact between the two metal terminals of the switch. The cantilever is pulled down by applying a pull-in voltage to the control electrode that is located below the middle portion of the cantilever while only the tip portion of the cantilever makes contact between the two terminals. Detailed analysis of bending of the cantilever for different pull-in voltages reveals some interesting facts. At low pull-in voltage the cantilever tip barely touches the two terminals, thus resulting in very less contact area. To increase contact area a very high pull-in voltage is applied, but it lifts the tip from the free end due to concave curving of the cantilever in the middle region of the cantilever where the electrode is located. Again it results in less contact area. Furthermore, the high pull-in voltage produces large stress at the base of the cantilever close to the anchor. Therefore, an optimum, pull-in voltage must exist at which the concave curving is eliminated and contact area is maximum. In this paper authors report the finding of optimum contact force and pull-in voltage.

  17. Contact-Free Cognitive Load Recognition Based on Eye Movement

    Directory of Open Access Journals (Sweden)

    Xin Liu

    2016-01-01

    Full Text Available The cognitive overload not only affects the physical and mental diseases, but also affects the work efficiency and safety. Hence, the research of measuring cognitive load has been an important part of cognitive load theory. In this paper, we proposed a method to identify the state of cognitive load by using eye movement data in a noncontact manner. We designed a visual experiment to elicit human’s cognitive load as high and low state in two light intense environments and recorded the eye movement data in this whole process. Twelve salient features of the eye movement were selected by using statistic test. Algorithms for processing some features are proposed for increasing the recognition rate. Finally we used the support vector machine (SVM to classify high and low cognitive load. The experimental results show that the method can achieve 90.25% accuracy in light controlled condition.

  18. Monitoring vertical wheel–rail contact forces based on freight wagon inverse modelling

    National Research Council Canada - National Science Library

    Sun, Yan Quan; Cole, Colin; Spiryagin, Maksym

    2015-01-01

    ...–rail contact dynamic forces. To evaluate and monitor the wheel–rail dynamic forces based on the accelerations on the wagon components, a two-dimensional inverse wagon model has been developed...

  19. General framework for dynamic large deformation contact problems based on phantom-node X-FEM

    Science.gov (United States)

    Broumand, P.; Khoei, A. R.

    2017-08-01

    This paper presents a general framework for modeling dynamic large deformation contact-impact problems based on the phantom-node extended finite element method. The large sliding penalty contact formulation is presented based on a master-slave approach which is implemented within the phantom-node X-FEM and an explicit central difference scheme is used to model the inertial effects. The method is compared with conventional contact X-FEM; advantages, limitations and implementational aspects are also addressed. Several numerical examples are presented to show the robustness and accuracy of the proposed method.

  20. Six Open Questions about the Migration of Engineered Nano-Objects from Polymer-Based Food Contact Materials: A Review

    DEFF Research Database (Denmark)

    Jokar, Maryam; Pedersen, Gitte Alsing; Löschner, Katrin

    2017-01-01

    The use of nanomaterials in food contact applications has created enormous interest in recent years. The potential migration of engineered nano-objects (ENOs) from food contact materials (FCMs) is one of the most important concerns regarding potential human exposure to ENOs and health risks....... This includes the very fundamental questions whether ENOs can migrate from FCMs at all and what the potential release mechanisms of ENOs could be. The inconsistency of findings from experimental studies is highlighted based on the example of silver nanoparticle migration from polymer-based FCMs. Challenges...... in detection and characterization of ENOs in migration studies and the suitability of the most frequently used analytical techniques are discussed. Further, this review questions the suitability of standard food simulants and migration test conditions for FCMs as well as of conventional mathematical migration...

  1. Prioritized Contact Transport Stream

    Science.gov (United States)

    Hunt, Walter Lee, Jr. (Inventor)

    2015-01-01

    A detection process, contact recognition process, classification process, and identification process are applied to raw sensor data to produce an identified contact record set containing one or more identified contact records. A prioritization process is applied to the identified contact record set to assign a contact priority to each contact record in the identified contact record set. Data are removed from the contact records in the identified contact record set based on the contact priorities assigned to those contact records. A first contact stream is produced from the resulting contact records. The first contact stream is streamed in a contact transport stream. The contact transport stream may include and stream additional contact streams. The contact transport stream may be varied dynamically over time based on parameters such as available bandwidth, contact priority, presence/absence of contacts, system state, and configuration parameters.

  2. Contact-free experimental determination of the static flexural spring constant of cantilever sensors using a microfluidic force tool

    Directory of Open Access Journals (Sweden)

    John D. Parkin

    2016-03-01

    Full Text Available Micro- and nanocantilevers are employed in atomic force microscopy (AFM and in micro- and nanoelectromechanical systems (MEMS and NEMS as sensing elements. They enable nanomechanical measurements, are essential for the characterization of nanomaterials, and form an integral part of many nanoscale devices. Despite the fact that numerous methods described in the literature can be applied to determine the static flexural spring constant of micro- and nanocantilever sensors, experimental techniques that do not require contact between the sensor and a surface at some point during the calibration process are still the exception rather than the rule. We describe a noncontact method using a microfluidic force tool that produces accurate forces and demonstrate that this, in combination with a thermal noise spectrum, can provide the static flexural spring constant for cantilever sensors of different geometric shapes over a wide range of spring constant values (≈0.8–160 N/m.

  3. Nanoscale contacts to organic molecules based on layered semiconductor substrates

    Energy Technology Data Exchange (ETDEWEB)

    Strobel, Sebastian

    2009-06-15

    This work reports on the integration of organic molecules as nanoelectronic device units on semiconductor substrates. Two novel preparation methods for sub-10-nm separated metal electrodes are presented using current microelectronics process technology. The first method utilises AlGaAs/GaAs heterostructures grown by molecular beam epitaxy (MBE) as mold to create planar metal electrodes employing a newly developed, high resolution nanotransfer printing (nTP) process. The second method uses commercially available Silicon-on-Insulator (SOI) substrates as base material for the fabrication of nanogap electrode devices. This sandwich-like material stack consists of a silicon substrate, a thin silicon oxide layer, and a capping silicon layer on top. Electronic transport measurements verified their excellent electrical properties at liquid helium temperatures. Specifically tailored nanogap devices featured an electrode insulation in the GW range even up to room temperature as well as within aqueous electrolyte solution. Finally, the well defined layer architecture facilitated the fabrication of electrodes with gap separations below-10-nm to be directly bridged by molecules. Approximately 12-nm-long conjugated molecules with extended -electron system were assembled onto the devices from solution. A large conductance gap was observed with a steep increase in current at a bias voltage of V{sub T}{approx}{+-}1.5 V. Theoretical calculations based on density functional theory and non-equilibrium Green's function formalism confirmed the measured non-linear IV-characteristics qualitatively and lead to the conclusion that the conductance gap mainly originates from the oxygen containing linker. Temperature dependent investigations of the conductance indicated a hopping charge transport mechanism through the central part of the molecule for bias voltages near but below V{sub T}. (orig.)

  4. Image based weighted center of proximity versus directly measured knee contact location during simulated gait.

    Science.gov (United States)

    Wang, Hongsheng; Chen, Tony; Koff, Matthew F; Hutchinson, Ian D; Gilbert, Susannah; Choi, Dan; Warren, Russell F; Rodeo, Scott A; Maher, Suzanne A

    2014-07-18

    To understand the mechanical consequences of knee injury requires a detailed analysis of the effect of that injury on joint contact mechanics during activities of daily living. Three-dimensional (3D) knee joint geometric models have been combined with knee joint kinematics to dynamically estimate the location of joint contact during physiological activities-using a weighted center of proximity (WCoP) method. However, the relationship between the estimated WCoP and the actual location of contact has not been defined. The objective of this study was to assess the relationship between knee joint contact location as estimated using the image-based WCoP method, and a directly measured weighted center of contact (WCoC) method during simulated walking. To achieve this goal, we created knee specific models of six human cadaveric knees from magnetic resonance imaging. All knees were then subjected to physiological loads on a knee simulator intended to mimic gait. Knee joint motion was captured using a motion capture system. Knee joint contact stresses were synchronously recorded using a thin electronic sensor throughout gait, and used to compute WCoC for the medial and lateral plateaus of each knee. WCoP was calculated by combining knee kinematics with the MRI-based knee specific model. Both metrics were compared throughout gait using linear regression. The anteroposterior (AP) location of WCoP was significantly correlated with that of WCoC on both tibial plateaus in all specimens (p0), but the correlation was not significant in the mediolateral (ML) direction for 4/6 knees (p>0.05). Our study demonstrates that while the location of joint contact obtained from 3D knee joint contact model, using the WCoP method, is significantly correlated with the location of actual contact stresses in the AP direction, that relationship is less certain in the ML direction. Copyright © 2014 Elsevier Ltd. All rights reserved.

  5. The Constructions of Attitudes about Homosexuality based on Contacts with Gays and Lesbians

    OpenAIRE

    Desarta Spahiu

    2016-01-01

    Main aim of this paper is to understand how discourse about homosexuality is premised upon the ways that people talk about homosexuality based in their personal contact with gays and lesbians. Evidences of this study suggest that people’s affective attitudes and moral values regarding homosexuality are related to personal contact with gays and lesbians as the most important predictors of attitudes. The set of data analyzed in this paper is comprised of 10 in-depth interviews with participants...

  6. Role of Metal Contacts in High-Performance Phototransistors Based on WSe 2 Monolayers

    KAUST Repository

    Zhang, Wenjing

    2014-08-26

    Phototransistors based on monolayer transition metal dichalcogenides (TMD) have high photosensitivity due to their direct band gap transition. However, there is a lack of understanding of the effect of metal contacts on the performance of atomically thin TMD phototransistors. Here, we fabricate phototransistors based on large-area chemical vapor deposition (CVD) tungsten diselenide (WSe2) monolayers contacted with the metals of different work function values. We found that the low Schottky-contact WSe2 phototransistors exhibit a very high photo gain (105) and specific detectivity (1014Jones), values higher than commercial Si- and InGaAs-based photodetectors; however, the response speed is longer than 5 s in ambient air. In contrast, the high Schottky-contact phototransistors display a fast response time shorter than 23 ms, but the photo gain and specific detectivity decrease by several orders of magnitude. Moreover, the fast response speed of the high Schottky-contact devices is maintained for a few months in ambient air. This study demonstrates that the contact plays an important role in TMD phototransistors, and barrier height tuning is critical for optimizing the photoresponse and photoresponsivity. © 2014 American Chemical Society.

  7. Prevalence of non-contact and contact childhood sexual abuse: An Internet-based sample of men who have sex with men in China.

    Directory of Open Access Journals (Sweden)

    Wenjian Xu

    Full Text Available The prevalence of childhood sexual abuse (CSA is high among Western men who have sex with men (MSM, and CSA is associated with certain socio-demographic variables and with human immunodeficiency virus (HIV status. Little is known about CSA among Chinese MSM; therefore, we explored the prevalence and frequency of non-contact (e.g., sexual invitations, exhibitionism and contact (e.g., intercourse, genital contact forms of CSA in an Internet-based sample of MSM in China. We also examined the associations between the participants' socio-demographic characteristics and HIV status, and their histories of CSA.We surveyed MSM from 30 Chinese provinces in 2014-2015; 1,030 (mean age = 25.15 years, SD = 6.32 and 1,020 (mean age = 25.05 years, SD = 5.95 respondents were eligible for inclusion in the non-contact and contact CSA groups, respectively.Prevalence of non-contact and contact CSA was 36.2% and 29.8%, respectively; 20.4% and 15.0% had experienced non-contact and contact CSA ≥ 3 times, respectively. Most respondents were young adults, well educated, single, had never "come out," and self-identified as gay or bisexual men. Univariate analyses showed that respondents who had experienced contact CSA were more likely to be HIV-positive than those who had never experienced contact CSA. Multivariate analyses showed that non-contact CSA was associated with less education, being in a relationship with a woman or a man, and having "come out." Contact CSA was associated with less education, higher income, and being in a relationship with a man. Respondents who had experienced non-contact CSA ≥ 3 times were more likely to be less educated, "out," and to be in a relationship with a woman or a man. Respondents who had experienced contact CSA ≥ 3 times were more likely to be less educated and to be in a relationship with a man.It is necessary to pay closer attention to CSA among MSM and other sexual minorities in China.

  8. Characterization of nanophotonic soft contact lenses based on poly (2-hydroxyethyl methacrylate and fullerene

    Directory of Open Access Journals (Sweden)

    Debeljković Aleksandra D.

    2013-01-01

    Full Text Available This work presents comparative research of characteristics of a basic and new nanophotonic material, the latter of which was obtained by incorporation fullerene, C60, in the base material for soft contact lenses. The basic (SL38 and nanophotonic materials (SL38-A for soft contact lenses were obtained by radical polymerization of 2-hydroxyethyl methacrylate and 2-hydroxyethyl methacrylate and fullerene, which were derived by the technology in the production lab of the company Soleko (Milan, Italy. The materials were used for production of soft contact lenses in the company Optix (Belgrade, Serbia for the purposes of this research. Fullerene was used due to its apsorption transmission characteristics in ultraviolet, visible and near infrared spectrum. For the purposes of material characterization for potential application as soft contact lenses, network parameters were calculated and SEM analysis of the materials was performed while the optical properties of the soft contact lenses were measured by a Rotlex device. The values of the diffusion exponent, n, close to 0.5 indicated Fick's kinetics corresponding to diffusion. The investigated hydrogels could be classified as nonporous hydrogels. With Rotlex device, values of optical power and map of defects were showed. The obtained values of optical power and map of defects showed that the optical power of synthesized nanophotonic soft contact lens is identical to the nominal value while this was not the case for the basic lens. Also, the quality of the nanophotonic soft contact lens is better than the basic soft contact lens. Hence, it is possible to synthesize new nanophotonic soft contact lenses of desired optical characteristics, implying possibilities for their application in this field.

  9. Evaluation of Tire/Surfacing/Base Contact Stresses and Texture Depth

    Directory of Open Access Journals (Sweden)

    W.J.vdM. Steyn

    2015-03-01

    Full Text Available Tire rolling resistance has a major impact on vehicle fuel consumption. Rolling resistance is the loss of energy due to the interaction between the tire and the pavement surface. This interaction is a complicated combination of stresses and strains which depend on both tire and pavement related factors. These include vehicle speed, vehicle weight, tire material and type, road camber, tire inflation pressure, pavement surfacing texture etc. In this paper the relationship between pavement surface texture depth and tire/surfacing contact stress and area is investigated. Texture depth and tire/surfacing contact stress were measured for a range of tire inflation pressures on five different pavement surfaces. In the analysis the relationship between texture and the generated contact stresses as well as the contact stress between the surfacing and base layer are presented and discussed, and the anticipated effect of these relationships on the rolling resistance of vehicles on the surfacings, and subsequent vehicle fuel economy discussed.

  10. Analysis on multifocal contact lens design based on optical power distribution with NURBS.

    Science.gov (United States)

    Vu, Lien T; Chen, Chao-Chang A; Shum, Patrick Joi-Tsang

    2017-10-01

    This paper aims to develop and analyze the design method of multifocal contact lenses to obtain curvature continuity in the optical surfaces with the high addition (Add) powers by adjusting non-uniform rational B-spline (NURBS) curves. The paper has developed mathematical formulae to generate the optical power distributions in which the powers continuously change from either near or distant center to the opposite focal length in the periphery of the optical region with different change rates and Add power values. This developed method can efficiently adjust and optimize three parameters, including control points, weight, and knots of the NURBS, to be anterior optical lens surface profiles to adapt for these given power profiles. The result shows that the proposed contact lenses not only achieve smooth and continuous anterior optical surfaces, but also satisfy various optical power distributions with high Add power values for different pupil diameters. Then, these designs of contact lenses can be feasibly converted to the computer-aided design format for analysis and manufacture for molding or single-point diamond turning. Experimental results of this method have been tested and proven when both the power distributions of simulation of lenses and the actual machined samples match the original specified powers provided by clinical demands of a multifocal contact lens. Future integration with variant clinical demands and optimization rules of lens design can be explored for a progressive contact lens.

  11. Chemical-Based Formulation Design: Virtual Experimentation

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    of databases with data of AIs used in different products (such as insect repellents), solvents classified in terms of special characteristics (such as solubility in water), and additives classified in terms of their application (such as aroma agents, wetting agents and preservatives). In addition, the software......This paper presents a software, the virtual Product-Process Design laboratory (virtual PPD-lab) and the virtual experimental scenarios for design/verification of consumer oriented liquid formulated products where the software can be used. For example, the software can be employed for the design......; the addition of the missing chemicals to an incomplete formulation and the verification of the final product. The software is based on a framework that allows quick implementation of different design/verification work-flows and their associated models, methods, tools and data. The software contains a suite...

  12. Parameter Characterization in Processing of Silver – Aluminum Based Electrical Contact Materials

    Directory of Open Access Journals (Sweden)

    Kumar S. Praveen

    2017-09-01

    Full Text Available An electrical contractor is one which plays significant role in day todays life in industries as well as in home appliances. In current scenario the materials for conducting purpose has an overwhelming research capability. Now a day the silver based electrical contact composite material have provided the potential applications in aerospace and automobile industries. Among silver based contact material the silver cadmium oxide and silver tin oxide plays a vital role in fabrication of electrical contactors. In this research an attempt has been made to study the influence of adding Aluminum with silver based electrical contact composite materials by two different processing routes namely stir-casting and powder metallurgy. Silver and aluminum matrix plays a virtual role in composite world owing to their highest conductivity. Optimum parameters were identified for attaining the maximum properties such as conductivity, hardness, density, and porosity of composition. By this better conducting property and mechanical property of the electrical contact can be improved by this system. Thus a screening test has be conducted with addition of Al with silver tin oxide compositions hence this paper aims to process the aluminum - silver based electrical contact materials by stir casting processing and powder metallurgy route and compare the results obtained.

  13. Evaluation performance of substitution matrices, based on contacts between residue terminal groups.

    Science.gov (United States)

    Vishnepolsky, Boris; Managadze, Grigol; Grigolava, Maya; Pirtskhalava, Malak

    2012-01-01

    Sequence alignment is a standard method for the estimation of the evolutionary, structural, and functional relationships among amino acid sequences. The quality of alignments depends on the used similarity matrix. Statistical contact potentials (CPs) contain information on contact propensities among residues in native protein structures. Substitution matrices (SMs) based on CPs are applicable for the comparison of distantly related sequences. Here, contact between amino acids was estimated on the basis of the evaluation of the distances between side-chain terminal groups (SCTGs), which are defined as the group of the side-chain heavy atoms with fixed distances between them. In this paper, two new types of CPs and similarity matrices have been constructed: one based on fixed cutoff distance obtained from geometric characteristics of the SCTGs (TGC1), while the other is distance-dependent potential (TGC2). These matrices are compared with other popular SMs. The performance of the matrices was evaluated by comparing sequence with structural alignments. The obtained results show that TGC2 has the best performance among contact-based matrices, but on the whole, contact-based matrices have slightly lower performance than other SMs except fold-level similarity.

  14. Effectiveness of contact-based education for reducing mental illness-related stigma in pharmacy students

    Directory of Open Access Journals (Sweden)

    Patten Scott B

    2012-12-01

    Full Text Available Abstract Background A strategy for reducing mental illness-related stigma in health-profession students is to include contact-based sessions in their educational curricula. In such sessions students are able to interact socially with a person that has a mental illness. We sought to evaluate the effectiveness of this strategy in a multi-centre study of pharmacy students. Methods The study was a randomized controlled trial conducted at three sites. Because it was necessary that all students receive the contact-based sessions, the students were randomized either to an early or late intervention, with the late intervention group not having participated in the contact-based education at the time when the primary outcome was assessed. The primary outcome, stigma, was assessed using an attitudes scale called the Opening Minds Survey for Health Care Providers (OMS-HC. Results We initially confirmed that outcomes were homogeneous across study centres, centre by group interaction, p = 0.76. The results were pooled across the three study centres. A significant reduction in stigma was observed in association with the contact-based sessions (mean change 4.3 versus 1.5, t=2.1, p=0.04. The effect size (Cohen’s d was 0.45. A similar reduction was seen in the control group when they later received the intervention. Conclusions Contact-based education is an effective method of reducing stigma during pharmacy education. These results add to a growing literature confirming the effectiveness of contact-based strategies for stigma reduction in health profession trainees.

  15. On the physically based modeling of surface tension and moving contact lines with dynamic contact angles on the continuum scale

    Science.gov (United States)

    Huber, M.; Keller, F.; Säckel, W.; Hirschler, M.; Kunz, P.; Hassanizadeh, S. M.; Nieken, U.

    2016-04-01

    The description of wetting phenomena is a challenging problem on every considerable length-scale. The behavior of interfaces and contact lines on the continuum scale is caused by intermolecular interactions like the Van der Waals forces. Therefore, to describe surface tension and the resulting dynamics of interfaces and contact lines on the continuum scale, appropriate formulations must be developed. While the Continuum Surface Force (CSF) model is well-engineered for the description of interfaces, there is still a lack of treatment of contact lines, which are defined by the intersection of an ending fluid interface and a solid boundary surface. In our approach we use a balance equation for the contact line and extend the Navier-Stokes equations in analogy to the extension of a two-phase interface in the CSF model. Since this model depicts a physically motivated approach on the continuum scale, no fitting parameters are introduced and the deterministic description leads to a dynamical evolution of the system. As verification of our theory, we show a Smoothed Particle Hydrodynamics (SPH) model and simulate the evolution of droplet shapes and their corresponding contact angles.

  16. Autonomous entropy-based intelligent experimental design

    Science.gov (United States)

    Malakar, Nabin Kumar

    2011-07-01

    The aim of this thesis is to explore the application of probability and information theory in experimental design, and to do so in a way that combines what we know about inference and inquiry in a comprehensive and consistent manner. Present day scientific frontiers involve data collection at an ever-increasing rate. This requires that we find a way to collect the most relevant data in an automated fashion. By following the logic of the scientific method, we couple an inference engine with an inquiry engine to automate the iterative process of scientific learning. The inference engine involves Bayesian machine learning techniques to estimate model parameters based upon both prior information and previously collected data, while the inquiry engine implements data-driven exploration. By choosing an experiment whose distribution of expected results has the maximum entropy, the inquiry engine selects the experiment that maximizes the expected information gain. The coupled inference and inquiry engines constitute an autonomous learning method for scientific exploration. We apply it to a robotic arm to demonstrate the efficacy of the method. Optimizing inquiry involves searching for an experiment that promises, on average, to be maximally informative. If the set of potential experiments is described by many parameters, the search involves a high-dimensional entropy space. In such cases, a brute force search method will be slow and computationally expensive. We develop an entropy-based search algorithm, called nested entropy sampling, to select the most informative experiment. This helps to reduce the number of computations necessary to find the optimal experiment. We also extended the method of maximizing entropy, and developed a method of maximizing joint entropy so that it could be used as a principle of collaboration between two robots. This is a major achievement of this thesis, as it allows the information-based collaboration between two robotic units towards a same

  17. Contact lens compliance among a group of young, university-based lens users in South India.

    Science.gov (United States)

    Noushad, Babu; Saoji, Yeshwant; Bhakat, Premjit; Thomas, Jyothi

    2012-01-01

    To investigate the rate of compliance with the soft contact lens care and maintenance procedures with a focus on contact lens wearing habits, cleaning and disinfecting procedures, and maintenance of lens care accessories in a group of young, university-based contact lens wearers Two hundred and sixteen young soft contact lens wearers with an age range of 18-22 years were selected conveniently from the student population of Manipal University, Manipal, India. After receiving informed consent from the participants, their level of compliance with contact lenses was assessed using a questionnaire. The mean (±SD) age of the participants was 21.86±2.35 years. Out of 216 subjects, only 34% of the lens users were identified to be compliant with the least level of compliance observed in the maintenance of lens care accessories. Conventional users showed significantly (p=0.001) better level of compliance compared to disposable wearers and so did the users who acquired their lenses from clinicians (p=0.001) compared to over-the-counter lens receipt. The gender (p=0.496) and years of experience in contact lens use (p=0.142) did not show any statistically significant difference in the level of compliance. This study demonstrated that non-compliance with lens care procedures among a group of young, university-based soft contact lens wearers is common. The results indicated that all subjects had some degree of non-compliance and the least level of compliance observed in the care of lens accessories.

  18. Experimental testing of a direct contact heat exchanger for geothermal brine. Final report, July 1, 1978-February 1, 1979

    Energy Technology Data Exchange (ETDEWEB)

    Urbanek, M.W.

    1979-12-01

    A series of direct contact heat exchanger (DCHX) experiments were conducted at the East Mesa Geothermal Test Site during the period July 1, 1978 to February 1, 1979. The purpose of these tests was to provide additional data necessary to better understand the thermal and hydraulic characteristics of the DCHX binary cycle loop components that may be used to extract energy from geothermal brines. Isobutane and Isopentane were tested as secondary working fluids. The analytical and experimental efforts were directed at the problems of working fluid loss in the effluent brine, carryover of water vapor with the vaporized secondary fluid and the free CO/sub 2/ content of the feed brine. The tests aimed at evaluating the heat transfer performance of various type tubes installed in vertical shell-and-tube secondary fluid condensers. Data was collected while operating a low temperature isopentane cycle with brine preflashed to 210 to 212/sup 0/F; the objective being to gain insight to waste heat recovery applications such as the Arkansas Power and Light project. Possible alternatives for isobutane recovery from the spent brine were investigated. A system was designed and the economic aspects studied.

  19. A reference guide to microbial cell surface hydrophobicity based on contact angles

    NARCIS (Netherlands)

    van der Mei, HC; Busscher, HJ; Bos, R.R.M.

    1998-01-01

    Acid-base interactions form the origin of the hydrophobicity of microbial cell-surfaces and can be quantitated from contact angle measurements on microbial lawns with water, formamide, methyleneiodide and/or alpha-bromonaphthalene. This review provides a reference guide to microbial cell surface

  20. [Airborne contact allergy provoked by kathon in water-based plastic paint].

    Science.gov (United States)

    Kristensen, Diana; Hein, Hans Ole; Weismann, Kaare

    2002-04-29

    We describe two cases of airborne contact allergy to plastic paint containing Kathon. Two women with known kathon allergy, aged 33 and 50 years, developed severe dermatitis and systemic reactions after painting their homes with water-based plastic paint with Kathon as preservative. Both required treatment with systemic steroids. On return to their homes, the symptoms immediately recurred, and they were forced to stay away for several weeks afterwards. Patients allergic to Kathon should be informed of the risk of airborne contact allergy when exposed to paints preserved with Kathon.

  1. Contact dermatitis to hair dyes in a Danish adult population: an interview-based study

    DEFF Research Database (Denmark)

    Søsted, H; Hesse, U; Menné, T

    2005-01-01

    ) was taken of the Danish adult population. Personal interview questions were asked regarding adverse skin reactions to hair dyes, either compatible with a classical allergic eczematous reaction with redness, scaling and itching or a severe allergic reaction with oedema of the forehead and face. The response......BACKGROUND: Contact allergy to hair dye ingredients is a well-known entity seen both in consumers using hair dyes and among hairdressers with occupational contact dermatitis. Surveys show that consumers with even severe adverse skin reactions to hair dyes only rarely contact the healthcare services....... The frequency of hair dye-induced skin reactions in the consumer population is unknown. OBJECTIVES: An epidemiological investigation with the aim of establishing the proportion of hair dye-induced skin reactions was performed in a population-based sample. METHODS: A representative random sample (n = 4000...

  2. Conjugate gradient based projection - A new explicit methodology for frictional contact

    Science.gov (United States)

    Tamma, Kumar K.; Li, Maocheng; Sha, Desong

    1993-01-01

    With special attention towards the applicability to parallel computation or vectorization, a new and effective explicit approach for linear complementary formulations involving a conjugate gradient based projection methodology is proposed in this study for contact problems with Coulomb friction. The overall objectives are focussed towards providing an explicit methodology of computation for the complete contact problem with friction. In this regard, the primary idea for solving the linear complementary formulations stems from an established search direction which is projected to a feasible region determined by the non-negative constraint condition; this direction is then applied to the Fletcher-Reeves conjugate gradient method resulting in a powerful explicit methodology which possesses high accuracy, excellent convergence characteristics, fast computational speed and is relatively simple to implement for contact problems involving Coulomb friction.

  3. Optimal contact definition for reconstruction of Contact Maps

    Directory of Open Access Journals (Sweden)

    Stehr Henning

    2010-05-01

    Full Text Available Abstract Background Contact maps have been extensively used as a simplified representation of protein structures. They capture most important features of a protein's fold, being preferred by a number of researchers for the description and study of protein structures. Inspired by the model's simplicity many groups have dedicated a considerable amount of effort towards contact prediction as a proxy for protein structure prediction. However a contact map's biological interest is subject to the availability of reliable methods for the 3-dimensional reconstruction of the structure. Results We use an implementation of the well-known distance geometry protocol to build realistic protein 3-dimensional models from contact maps, performing an extensive exploration of many of the parameters involved in the reconstruction process. We try to address the questions: a to what accuracy does a contact map represent its corresponding 3D structure, b what is the best contact map representation with regard to reconstructability and c what is the effect of partial or inaccurate contact information on the 3D structure recovery. Our results suggest that contact maps derived from the application of a distance cutoff of 9 to 11Å around the Cβ atoms constitute the most accurate representation of the 3D structure. The reconstruction process does not provide a single solution to the problem but rather an ensemble of conformations that are within 2Å RMSD of the crystal structure and with lower values for the pairwise average ensemble RMSD. Interestingly it is still possible to recover a structure with partial contact information, although wrong contacts can lead to dramatic loss in reconstruction fidelity. Conclusions Thus contact maps represent a valid approximation to the structures with an accuracy comparable to that of experimental methods. The optimal contact definitions constitute key guidelines for methods based on contact maps such as structure prediction through

  4. Diagnosis of constant faults in read-once contact networks over finite bases

    KAUST Repository

    Busbait, Monther I.

    2015-03-01

    We study the depth of decision trees for diagnosis of constant 0 and 1 faults in read-once contact networks over finite bases containing only indecomposable networks. For each basis, we obtain a linear upper bound on the minimum depth of decision trees depending on the number of edges in the networks. For bases containing networks with at most 10 edges we find coefficients for linear bounds which are close to sharp. © 2014 Elsevier B.V. All rights reserved.

  5. Diagnosis of three types of constant faults in read-once contact networks over finite bases

    KAUST Repository

    Busbait, Monther I.

    2016-03-24

    We study the depth of decision trees for diagnosis of three types of constant faults in read-once contact networks over finite bases containing only indecomposable networks. For each basis and each type of faults, we obtain a linear upper bound on the minimum depth of decision trees depending on the number of edges in networks. For bases containing networks with at most 10 edges, we find sharp coefficients for linear bounds.

  6. Design, fabrication and skin-electrode contact analysis of polymer microneedle-based ECG electrodes

    Science.gov (United States)

    O'Mahony, Conor; Grygoryev, Konstantin; Ciarlone, Antonio; Giannoni, Giuseppe; Kenthao, Anan; Galvin, Paul

    2016-08-01

    Microneedle-based ‘dry’ electrodes have immense potential for use in diagnostic procedures such as electrocardiography (ECG) analysis, as they eliminate several of the drawbacks associated with the conventional ‘wet’ electrodes currently used for physiological signal recording. To be commercially successful in such a competitive market, it is essential that dry electrodes are manufacturable in high volumes and at low cost. In addition, the topographical nature of these emerging devices means that electrode performance is likely to be highly dependent on the quality of the skin-electrode contact. This paper presents a low-cost, wafer-level micromoulding technology for the fabrication of polymeric ECG electrodes that use microneedle structures to make a direct electrical contact to the body. The double-sided moulding process can be used to eliminate post-process via creation and wafer dicing steps. In addition, measurement techniques have been developed to characterize the skin-electrode contact force. We perform the first analysis of signal-to-noise ratio dependency on contact force, and show that although microneedle-based electrodes can outperform conventional gel electrodes, the quality of ECG recordings is significantly dependent on temporal and mechanical aspects of the skin-electrode interface.

  7. Contact lens trends over three decades in a hospital-based practice in India.

    Science.gov (United States)

    Rajan, Rajni; Mahadevan, Rajeswari; Thomas, Ann Mary; Bhattacharjee, Pradipta

    2017-09-26

    Contact lens fittings in a hospital-based practice are different from those in private practices because of specialised conditions. Few studies have been published on material preferences of such wearers, especially in long-term wearers. The aim of this study is to document contact lens prescribing trends in a hospital-based practice among long-term lens wearers and to identify their demographic profile. Subjects reporting to a contact lens clinic of a tertiary eye-care centre in India from 1 January 2014 to 31 December 2014, with a minimum of five years of lens wear, were included in the study. Data were collected retrospectively from the electronic medical charts of these subjects. Three hundred and sixty subjects were included in the study. The average duration of contact lens wear among the subjects was 9 ± 5 years (range: 5-35 years). The average age of the subjects was 31.38 ± 11.75 years (age range: 5-78 years). Hydrogel material and soft spherical type were preferred by most of the soft lens wearers (53 per cent). Eighty per cent of subjects followed hand hygiene and cleaning regimen practices. The preference for monthly replacement lenses and silicone hydrogel material increased over the years. Regular after-care consultations could enforce the need for compliance with hand hygiene and cleaning regimens among lens wearers. © 2017 Optometry Australia.

  8. Non-contact dual pulse Doppler system based respiratory and heart rates estimation for CHF patients.

    Science.gov (United States)

    Tran, Vinh Phuc; Ali Al-Jumaily, Adel

    2015-01-01

    Long term continuous patient monitoring is required in many health systems for monitoring and analytical diagnosing purposes. Most of monitoring systems had shortcomings related to their functionality or patient comfortably. Non-contact continuous monitoring systems have been developed to address some of these shortcomings. One of such systems is non-contact physiological vital signs assessments for chronic heart failure (CHF) patients. This paper presents a novel automated estimation algorithm for the non-contact physiological vital signs assessments for CHF patients based on a patented novel non-contact biomotion sensor. A database consists of twenty CHF patients with New York Heart Association (NYHA) heart failure Classification Class II & III, whose underwent full Polysomnography (PSG) analysis for the diagnosis of sleep apnea, disordered sleep, or both, were selected for the study. The patients mean age is 68.89 years, with mean body weight of 86.87 kg, mean BMI of 28.83 (obesity) and mean recorded sleep duration of 7.78 hours. The propose algorithm analyze the non-contact biomotion signals and estimate the patients' respiratory and heart rates. The outputs of the algorithm are compared with gold-standard PSG recordings. Across all twenty patients' recordings, the respiratory rate estimation median accuracy achieved 92.4689% with median error of ± 1.2398 breaths per minute. The heart rate estimation median accuracy achieved 88.0654% with median error of ± 7.9338 beats per minute. Due to the good performance of the propose novel automated estimation algorithm, the patented novel non-contact biomotion sensor can be an excellent tool for long term continuous sleep monitoring for CHF patients in the home environment in an ultra-convenient fashion.

  9. AlGaInN-based light emitting diodes with a transparent p-contact based on thin ITO films

    Energy Technology Data Exchange (ETDEWEB)

    Smirnova, I. P., E-mail: irina@quantum.ioffe.ru; Markov, L. K.; Pavlyuchenko, A. S. [Russian Academy of Sciences, Ioffe Physical Technical Institute (Russian Federation); Kukushkin, M. V. [ZAO Innovation Company ' TETIS' (Russian Federation)

    2012-03-15

    A method for obtaining transparent conductive ITO (indium-tin oxide) films aimed for use in light emitting diodes of the blue spectral range is developed. The peak external quantum efficiency of light-emitting diodes with a p-contact based on the obtained films reaches 25%, while for similar light-emitting diodes with a standard semitransparent metal contact, it is <10%. An observed increase in the direct voltage drop from 3.15 to 3.37 V does not significantly affect the possibility of applying these films in light-emitting diodes since the optical power of light-emitting diodes with a transparent p-contact based on ITO films exceeds that of chips with metal semitransparent p-contacts with a working current of 20 mA by a factor of almost 2.5. Light-emitting diodes with p-contacts based on ITO films successfully withstand a pumping current that exceeds their calculated working current by a factor of 5 without the appearance of any signs of degradation.

  10. Chemicals-Based Formulation Design: Virtual Experimentations

    DEFF Research Database (Denmark)

    Conte, Elisa; Gani, Rafiqul

    2011-01-01

    This paper presents a systematic procedure for virtual experimentations related to the design of liquid formulated products. All the experiments that need to be performed when designing a liquid formulated product (lotion), such as ingredients selection and testing, solubility tests, property mea...... on the design of an insect repellent lotion will show that the software is an essential instrument in decision making, and that it reduces time and resources since experimental efforts can be focused on one or few product alternatives.......This paper presents a systematic procedure for virtual experimentations related to the design of liquid formulated products. All the experiments that need to be performed when designing a liquid formulated product (lotion), such as ingredients selection and testing, solubility tests, property...... measurements, can now be performed through the virtual Product-Process Design laboratory [[1], [2] and [3

  11. Experimental demonstration of water based tunable metasurface

    DEFF Research Database (Denmark)

    Odit, Mikhail; Kapitanova, Polina; Andryieuski, Andrei

    2016-01-01

    A simple dynamically tunable metasurface (two-dimensional metamaterial) operating at microwave frequencies is developed and experimentally investigated. Conceptually, the simplicity of the approach is granted by reconfigurable properties of unit cells partially filled with distilled water....... The transmission spectra of the metasurface for linear and circular polarizations of the incident wave were experimentally measured under the metasurface rotation around a horizontal axis. The changes in the transmission coefficient magnitude up to 8 dB at 1.25 GHz are reported while rotating the metasurface...

  12. Acceptable risk of contact allergy in the general population assessed by CE-DUR--a method to detect and categorize contact allergy epidemics based on patient data

    DEFF Research Database (Denmark)

    Thyssen, Jacob Pontoppidan; Menné, Torkil; Schnuch, Axel

    2009-01-01

    population by using a new epidemiological tool. The clinical epidemiology (CE) and drug utilization research (DUR) method recently estimated the 10-year contact allergy prevalence in the general population in Germany and Denmark based on patch test reading data in combination with an estimate of the number...

  13. Nonadhesive, silica nanoparticles-based brush-coated contact lens casesCompromising between ease of cleaning and microbial transmission to contact lenses

    NARCIS (Netherlands)

    Qu, Wenwen; Hooymans, Johanna M. M.; Qiu, Jun; de-Bont, Nik; Gelling, Onko-Jan; van der Mei, Henny C.; Busscher, Henk J.

    Surface properties of lens cases are determinant for their cleanability and for microbial transmission from lens cases to contact lenses (CLs). PEG-polymer-brush-coatings are known to decrease microbial adhesion more than other surface-coatings. Here, we applied a robust, silica nanoparticles-based

  14. The Constructions of Attitudes about Homosexuality based on Contacts with Gays and Lesbians

    Directory of Open Access Journals (Sweden)

    Desarta Spahiu

    2016-11-01

    Full Text Available Main aim of this paper is to understand how discourse about homosexuality is premised upon the ways that people talk about homosexuality based in their personal contact with gays and lesbians. Evidences of this study suggest that people’s affective attitudes and moral values regarding homosexuality are related to personal contact with gays and lesbians as the most important predictors of attitudes. The set of data analyzed in this paper is comprised of 10 in-depth interviews with participants with various demographic characteristics. Qualitative analysis of the individual interviews shows how people discursively construct opinions about homosexuality based in a specific conversational context, by drawing on elements of their cultural repertoires, such as life experiences relating to contacts with gays and lesbians. First, I explain that people’s understandings of homosexuality are of fundamental importance in shaping how they talk about it. Second, I analyze that people’s understandings of homosexuality are composed of a variety of life experiences with gays and lesbians, which are themselves complex and not necessarily ideologically correlated. Of particular importance is a person’s tacit definition of homosexuality. It is shaped by a person’s cohort and religious ideologies, but it is also shaped by the extent of their contact with and acceptance of the cultural construction of homosexuality that is dominant during a given period. Finally, I interpret how the nature of a persons’ contact with gays and lesbians, their exposure to gays and lesbians and the composition of their social networks complicates the analysis of social generational change with the homosexuality discourse.

  15. Impact of illumination on model-based SRAF placement for contact patterning

    Science.gov (United States)

    Sturtevant, John L.; Jayaram, Srividya; El-Sewefy, Omar; Dave, Aasutosh; LaCour, Pat

    2010-04-01

    Sub-Resolution Assist Features (SRAFs) have been used extensively to improve the process latitude for isolated and semi-isolated features in conjunction with off-axis illumination. These SRAFs have typically been inserted based upon rules which assign a global SRAF size and proximity to target shapes. Additional rules govern the relationship of assist features to one another, and for random logic contact layers, the overall ruleset can become rather complex. It has been shown that model-based placement of SRAFs for contact layers can result in better worst-case process window than that obtained with rules, and various approaches have been applied to affect such placement. The model comprehends the specific illumination being used, and places assist features according to that model in the optimum location for each contact hole. This paper examines the impact of various illumination schemes on model-based SRAF placement, and compares the resulting process windows. Both standard illumination schemes and more elaborate pixel-based illumination pupil fills are considered.

  16. Simulation Research on Micro Contact Based on Force in Silicon Wafer Rotation Grinding

    Science.gov (United States)

    Ren, Qinglei; Wei, Xin; Xie, Xiaozhu; Hu, Wei

    2017-10-01

    Silicon wafer rotation grinding with cup type diamond wheel is a typical ultra precision grinding process. In this paper, a simulation model based on force for micro contact between wheel micro unit and silicon wafer is established from the stable ductile grinding process. Micro contact process in grinding is simulated using the nonlinear explicit finite element analysis software LS-DYNA. The stress-strain results on silicon wafer and wheel micro unit are analyzed by finite element method. The results show that the critical displacement and load corresponding elastic to plastic - plastic to brittle exist on silicon wafer. In silicon plastic zone tangential sliding can produce plastic groove and uplift. Wear of wheel micro unit can be based on the simulation data to judge. The research provides support for wafer grinding and wheel wear mechanism.

  17. Optical properties of photodetectors based on single GaN nanowires with a transparent graphene contact

    Energy Technology Data Exchange (ETDEWEB)

    Babichev, A. V., E-mail: A.Babichev@mail.ioffe.ru [Russian Academy of Sciences, Ioffe Institute (Russian Federation); Zhang, H.; Guan, N. [University Paris Saclay, Institut d’Electronique Fondamentale, UMR 8622 CNRS (France); Egorov, A. Yu. [ITMO University (Russian Federation); Julien, F. H.; Messanvi, A. [University Paris Saclay, Institut d’Electronique Fondamentale, UMR 8622 CNRS (France); Durand, C.; Eymery, J. [University Grenoble Alpes (France); Tchernycheva, M. [University Paris Saclay, Institut d’Electronique Fondamentale, UMR 8622 CNRS (France)

    2016-08-15

    We report the fabrication and optical and electrical characterization of photodetectors for the UV spectral range based on single p–n junction nanowires with a transparent contact of a new type. The contact is based on CVD-grown (chemical-vapor deposition) graphene. The active region of the nitride nanowires contains a set of 30 radial In{sub 0.18}Ga{sub 0.82}N/GaN quantum wells. The structure is grown by metal-organic vaporphase epitaxy. The photodetectors are fabricated using electron-beam lithography. The current–voltage characteristics exhibit a rectifying behavior. The spectral sensitivity of the photodetector is recorded starting from 3 eV and extending far in the UV range. The maximal photoresponse is observed at a wavelength of 367 nm (sensitivity 1.9 mA/W). The response switching time of the photodetector is less than 0.1 s.

  18. Sequential experimental design based generalised ANOVA

    Energy Technology Data Exchange (ETDEWEB)

    Chakraborty, Souvik, E-mail: csouvik41@gmail.com; Chowdhury, Rajib, E-mail: rajibfce@iitr.ac.in

    2016-07-15

    Over the last decade, surrogate modelling technique has gained wide popularity in the field of uncertainty quantification, optimization, model exploration and sensitivity analysis. This approach relies on experimental design to generate training points and regression/interpolation for generating the surrogate. In this work, it is argued that conventional experimental design may render a surrogate model inefficient. In order to address this issue, this paper presents a novel distribution adaptive sequential experimental design (DA-SED). The proposed DA-SED has been coupled with a variant of generalised analysis of variance (G-ANOVA), developed by representing the component function using the generalised polynomial chaos expansion. Moreover, generalised analytical expressions for calculating the first two statistical moments of the response, which are utilized in predicting the probability of failure, have also been developed. The proposed approach has been utilized in predicting probability of failure of three structural mechanics problems. It is observed that the proposed approach yields accurate and computationally efficient estimate of the failure probability.

  19. Ciprofloxacin interaction with silicon-based and conventional hydrogel contact lenses.

    Science.gov (United States)

    Karlgard, C C S; Jones, L W; Moresoli, C

    2003-04-01

    Hydrogel contact lenses can be used as bandage lenses to protect the corneal surface after injury. The use of novel silicon-based hydrogel lens materials as bandage lenses has not gained widespread acceptance. As a first step toward advocating their usefulness as bandage lenses, their interaction with ocular pharmaceuticals must be understood because topical agents are often administered in conjunction with bandage lenses. The in vitro uptake and release of ciprofloxacin from silicone-based hydrogel (SH) and conventional pHEMA-based (CH) hydrogel contact lenses was examined by spectrophotometric evaluation of the drug concentration in saline solution. The hydrogel contact lenses tested showed similar drug uptake (average 1800 microg/lens) but different levels of drug release. Multiphoton laser microscopy indicated that ciprofloxacin was distributed throughout the lens thickness, with higher levels of drug at the surface owing to drug precipitation. The drug adsorption onto the lenses was partially reversible. The SH lenses released a lower amount of drug than CH lenses (72 vs. 168 microg/lens). Ionic lenses released less drug than non-ionic lenses (127 vs. 151 microg/lens). The differences in ciprofloxacin uptake and release between SH and CH materials may not be clinically significant because the amount of drug released from all lenses would be above the MIC(90) of ciprofloxacin for common ocular pathogens. These results indicate that material properties have a significant impact on drug-lens interactions.

  20. Pathogen transfer through environment-host contact: an agent-based queueing theoretic framework.

    Science.gov (United States)

    Chen, Shi; Lenhart, Suzanne; Day, Judy D; Lee, Chihoon; Dulin, Michael; Lanzas, Cristina

    2017-11-02

    Queueing theory studies the properties of waiting queues and has been applied to investigate direct host-to-host transmitted disease dynamics, but its potential in modelling environmentally transmitted pathogens has not been fully explored. In this study, we provide a flexible and customizable queueing theory modelling framework with three major subroutines to study the in-hospital contact processes between environments and hosts and potential nosocomial pathogen transfer, where environments are servers and hosts are customers. Two types of servers with different parameters but the same utilization are investigated. We consider various forms of transfer functions that map contact duration to the amount of pathogen transfer based on existing literature. We propose a case study of simulated in-hospital contact processes and apply stochastic queues to analyse the amount of pathogen transfer under different transfer functions, and assume that pathogen amount decreases during the inter-arrival time. Different host behaviour (feedback and non-feedback) as well as initial pathogen distribution (whether in environment and/or in hosts) are also considered and simulated. We assess pathogen transfer and circulation under these various conditions and highlight the importance of the nonlinear interactions among contact processes, transfer functions and pathogen demography during the contact process. Our modelling framework can be readily extended to more complicated queueing networks to simulate more realistic situations by adjusting parameters such as the number and type of servers and customers, and adding extra subroutines. © The authors 2017. Published by Oxford University Press on behalf of the Institute of Mathematics and its Applications. All rights reserved.

  1. Contact-Free Detection of Obstructive Sleep Apnea Based on Wavelet Information Entropy Spectrum Using Bio-Radar

    Directory of Open Access Journals (Sweden)

    Fugui Qi

    2016-08-01

    Full Text Available Judgment and early danger warning of obstructive sleep apnea (OSA is meaningful to the diagnosis of sleep illness. This paper proposed a novel method based on wavelet information entropy spectrum to make an apnea judgment of the OSA respiratory signal detected by bio-radar in wavelet domain. It makes full use of the features of strong irregularity and disorder of respiratory signal resulting from the brain stimulation by real, low airflow during apnea. The experimental results demonstrated that the proposed method is effective for detecting the occurrence of sleep apnea and is also able to detect some apnea cases that the energy spectrum method cannot. Ultimately, the comprehensive judgment accuracy resulting from 10 groups of OSA data is 93.1%, which is promising for the non-contact aided-diagnosis of the OSA.

  2. Non-contact evaluation of milk-based products using air-coupled ultrasound

    Science.gov (United States)

    Meyer, S.; Hindle, S. A.; Sandoz, J.-P.; Gan, T. H.; Hutchins, D. A.

    2006-07-01

    An air-coupled ultrasonic technique has been developed and used to detect physicochemical changes of liquid beverages within a glass container. This made use of two wide-bandwidth capacitive transducers, combined with pulse-compression techniques. The use of a glass container to house samples enabled visual inspection, helping to verify the results of some of the ultrasonic measurements. The non-contact pulse-compression system was used to evaluate agglomeration processes in milk-based products. It is shown that the amplitude of the signal varied with time after the samples had been treated with lactic acid, thus promoting sample destabilization. Non-contact imaging was also performed to follow destabilization of samples by scanning in various directions across the container. The obtained ultrasonic images were also compared to those from a digital camera. Coagulation with glucono-delta-lactone of skim milk poured into this container could be monitored within a precision of a pH of 0.15. This rapid, non-contact and non-destructive technique has shown itself to be a feasible method for investigating the quality of milk-based beverages, and possibly other food products.

  3. Non-Contact Plant Growth Measurement Method and System Based on Ubiquitous Sensor Network Technologies

    Directory of Open Access Journals (Sweden)

    Intae Ryoo

    2011-04-01

    Full Text Available This paper proposes a non-contact plant growth measurement system using infrared sensors based on the ubiquitous sensor network (USN technology. The proposed system measures plant growth parameters such as the stem radius of plants using real-time non-contact methods, and generates diameter, cross-sectional area and thickening form of plant stems using this measured data. Non-contact sensors have been used not to cause any damage to plants during measurement of the growth parameters. Once the growth parameters are measured, they are transmitted to a remote server using the sensor network technology and analyzed in the application program server. The analyzed data are then provided for administrators and a group of interested users. The proposed plant growth measurement system has been designed and implemented using fixed-type and rotary-type infrared sensor based measurement methods and devices. Finally, the system performance is compared and verified with the measurement data that have been obtained by practical field experiments.

  4. Non-Contact Plant Growth Measurement Method and System Based on Ubiquitous Sensor Network Technologies

    Science.gov (United States)

    Suk, Jinweon; Kim, Seokhoon; Ryoo, Intae

    2011-01-01

    This paper proposes a non-contact plant growth measurement system using infrared sensors based on the ubiquitous sensor network (USN) technology. The proposed system measures plant growth parameters such as the stem radius of plants using real-time non-contact methods, and generates diameter, cross-sectional area and thickening form of plant stems using this measured data. Non-contact sensors have been used not to cause any damage to plants during measurement of the growth parameters. Once the growth parameters are measured, they are transmitted to a remote server using the sensor network technology and analyzed in the application program server. The analyzed data are then provided for administrators and a group of interested users. The proposed plant growth measurement system has been designed and implemented using fixed-type and rotary-type infrared sensor based measurement methods and devices. Finally, the system performance is compared and verified with the measurement data that have been obtained by practical field experiments. PMID:22163849

  5. Self-powered, ultrasensitive, flexible tactile sensors based on contact electrification.

    Science.gov (United States)

    Zhu, Guang; Yang, Wei Qing; Zhang, Tiejun; Jing, Qingshen; Chen, Jun; Zhou, Yu Sheng; Bai, Peng; Wang, Zhong Lin

    2014-06-11

    Tactile/touch sensing is essential in developing human-machine interfacing and electronic skins for areas such as automation, security, and medical care. Here, we report a self-powered triboelectric sensor based on flexible thin-film materials. It relies on contact electrification to generate a voltage signal in response to a physical contact without using an external power supply. Enabled by the unique sensing mechanism and surface modification by polymer-nanowires, the triboelectric sensor shows an exceptional pressure sensitivity of 44 mV/Pa (0.09% Pa(-1)) and a maximum touch sensitivity of 1.1 V/Pa (2.3% Pa(-1)) in the extremely low-pressure region (system is further developed. Diverse applications of the system are demonstrated, explicitly indicating a variety of immediate uses in human-electronics interface, automatic control, surveillance, remote operation, and security systems.

  6. Experimental study on the influence of the contact pressure to transmittance and reflectance spectra by near infrared spectroscopy

    Science.gov (United States)

    Jiang, Jingying; Li, Si; Wang, Tianpei; Li, Lin; Liu, Jiajia; Xu, Kexin

    2017-03-01

    Near Infrared Spectroscopy (NIRS) technology has been recognized as one of the most promising non-invasive blood glucose measurement methods due to its convenience, high efficiency, noninvasiveness, and real-time monitoring. We build a system to measure transmittance and reflectance within NIR range simultaneously. And contact measuring method has been performed in order to reduce the influence of specular reflectance of the measured skin tissue. However, in this way, the optical probe could press the skin tissue and make it distorted, which might make the internal structure and the constituent distribution of tissue changed and further the tissue optical parameter changed. This could eventually change the distribution of transmittance spectra and reflectance spectra. In this talk, we collect the transmittance spectra and the diffused reflectance spectra of human earlobe within the wavelength of 900-1700nm under the different contact pressures. The results show that the diffused reflectance spectra decrease and the diffused transmittance spectra increase with the increase of the contact pressure between the probe and the earlobe. In order to improve the precision and stability of NIRS, the contact position of the deformation of 0.75mm is determined to be an optimal contact state measurement position.

  7. 2D halide perovskite-based van der Waals heterostructures: contact evaluation and performance modulation

    Science.gov (United States)

    Guo, Yaguang; Saidi, Wissam A.; Wang, Qian

    2017-09-01

    Halide perovskites and van der Waals (vdW) heterostructures are both of current interest owing to their novel properties and potential applications in nano-devices. Here, we show the great potential of 2D halide perovskite sheets (C4H9NH3)2PbX4 (X  =  Cl, Br and I) that were synthesized recently (Dou et al 2015 Science 349 1518-21) as the channel materials contacting with graphene and other 2D metallic sheets to form van der Waals heterostructures for field effect transistor (FET). Based on state-of-the-art theoretical simulations, we show that the intrinsic properties of the 2D halide perovskites are preserved in the heterojunction, which is different from the conventional contact with metal surfaces. The 2D halide perovskites form a p-type Schottky barrier (Φh) contact with graphene, where tunneling barrier exists, and a negative band bending occurs at the lateral interface. We demonstrate that the Schottky barrier can be turned from p-type to n-type by doping graphene with nitrogen atoms, and a low-Φh or an Ohmic contact can be realized by doping graphene with boron atoms or replacing graphene with other high-work-function 2D metallic sheets such as ZT-MoS2, ZT-MoSe2 and H-NbS2. This study not only predicts a 2D halide perovskite-based FETs, but also enhances the understanding of tuning Schottky barrier height in device applications.

  8. On Experimental Research in Sampling-based Motion Planning

    NARCIS (Netherlands)

    Geraerts, R.J.

    2006-01-01

    In robotics research, it is often difficult to compare and evaluate techniques experimentally. This paper identifies these difficulties and provides solutions based on our work during the last four years in the field of sampling-based motion planning.

  9. Investigation of Ni/Ag contact to p-GaN with an O{sub 2} plasma treatment and its application to GaN-based LEDs

    Energy Technology Data Exchange (ETDEWEB)

    Lin, Nan-Ming [Department of Materials Science and Engineering, Institute of Nanotechnology and Microsystems Engineering, National Cheng Kung University, Tainan 701 (China); Shei, Shih-Chang [Department of Electrical Engineering, National University of Tainan, Tainan 700 (China); Chang, Shoou-Jinn [Department of Materials Science and Engineering, Institute of Nanotechnology and Microsystems Engineering, National Cheng Kung University, Tainan 701 (China); Department of Electrical Engineering, Institute of Microelectronics, Advanced Optoelectronic Technology Center, Center for Micro/Nano Science and Technology, National Cheng Kung University, Tainan 701 (China)

    2012-08-15

    In this paper, the contact structure of Ni-Ag/p-GaN with different O{sub 2} plasma treatment times for 1 and 5 min was utilized for investigation. From experimental results, the Ni-Ag contact to p-GaN with different O{sub 2} plasma treatment for 1 and 5 min reveals Schottky behaviors. Based on the variation of the specific contact resistance with respect to temperature, the dominant transport mechanism of Ni-Ag/p-GaN structure presented form thermionic emission to field emission as increasing time from 1 to 5 min. From the X-ray photoelectron spectroscopy (XPS) results, the increase of the N vacancies and antisite defects (O{sub N}) would enhance the resistance of the treated p-GaN underneath the contact, which would make the Ni-Ag/p-GaN contact reveal Schottky behavior. With a 20 mA current injection, the operation voltage of light-emitting diodes (LEDs) with Ni/Ag contact to p-GaN through O{sub 2} plasma treatment 400 W-5 min was 3.13 V larger than the LEDs with Ni/Ag contact to p-GaN through O{sub 2} plasma treatment 400 W-1 min. This is due to the larger specific contact resistance. The 3.13 V operation voltage is still good and acceptable. Furthermore, the largest output power among all devices can be achieved. Besides, the reliability is still good. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  10. Extended Ciprofloxacin Release Using Vitamin E Diffusion Barrier From Commercial Silicone-Based Soft Contact Lenses.

    Science.gov (United States)

    Shayani Rad, Maryam; Mohajeri, Seyed Ahmad

    2017-03-01

    Ciprofloxacin (Cipro) is an antibiotic, widely used in form of ophthalmic drops (0.3%) for the treatment of eye infections. In this study, vitamin E was used as a hydrophobic barrier to improve and prolong the amount and time of Cipro release from silicone-based soft contact lenses. Three different commercial contact lenses (Air Optix, Biofinity, and Acuvue Oasys) were soaked in vitamin E solutions (0.1 and 0.2 g/mL). The effect of vitamin E on Cipro loading amount and drug releasing profile was evaluated in artificial tear. Swelling properties and diameter changes of the lenses were also investigated in aqueous media in presence and absence of vitamin E. The data indicated that vitamin E, as a hydrophobic barrier, significantly decreased the water content of silicone-based soft contact lenses. After vitamin E loading, a 5% to 18% increase was observed in lens diameter in the hydrated state, whereas the lens diameter increased by 11% to 23% in the dry state. In all commercial lenses, vitamin E loading in a 0.2-g/mL solution caused a 27.94% to 37.08% increase in Cipro binding. The results indicated that applying vitamin E loading solutions, with 0.1 and 0.2 g/mL concentrations, could effectively enhance Cipro release time from 2 hr (in a pure non-vitamin E-loaded lens) to 14 to 17 and 30 to 33 days, respectively. These values showed an increase by a factor of 168 to 204 and 360 to 396 in Cipro release time after using vitamin E loading solutions with 0.1 and 0.2 g/mL concentrations, respectively, compared with pure non-vitamin E-loaded soft contact lenses. This study indicated that vitamin E acts as an effective hydrophobic barrier, in increasing the Cipro loading capacity of silicone-based contact lenses and prolonging the drug release into the artificial tear.

  11. Acousto-optic deflector based on a paratellurite crystal using broadband acoustic adhesive contact

    Science.gov (United States)

    Antonov, S. N.

    2017-07-01

    A broadband acoustic matching of a piezoelectric transducer made of a lithium niobate crystal with an acousto-optic TeO2 crystal has been studied. The transducer is acoustically attached to the crystal by the method of adhesive contact. The experimental method of creating a piezoelectric transducer with an acoustic matching layer from a tin film is developed. The conditions of the optimal technological regime when applying the matching layer are determined. The results of the research are used in creating a broadband high-performance deflector with a central ultrasound frequency of 37 MHz, with the frequency band scanning more than 30 MHz, and a diffraction efficiency of about 90% at a wavelength of 1.06 μm.

  12. Neonatal non-contact respiratory monitoring based on real-time infrared thermography

    Directory of Open Access Journals (Sweden)

    Abbas Abbas K

    2011-10-01

    Full Text Available Abstract Background Monitoring of vital parameters is an important topic in neonatal daily care. Progress in computational intelligence and medical sensors has facilitated the development of smart bedside monitors that can integrate multiple parameters into a single monitoring system. This paper describes non-contact monitoring of neonatal vital signals based on infrared thermography as a new biomedical engineering application. One signal of clinical interest is the spontaneous respiration rate of the neonate. It will be shown that the respiration rate of neonates can be monitored based on analysis of the anterior naris (nostrils temperature profile associated with the inspiration and expiration phases successively. Objective The aim of this study is to develop and investigate a new non-contact respiration monitoring modality for neonatal intensive care unit (NICU using infrared thermography imaging. This development includes subsequent image processing (region of interest (ROI detection and optimization. Moreover, it includes further optimization of this non-contact respiration monitoring to be considered as physiological measurement inside NICU wards. Results Continuous wavelet transformation based on Debauches wavelet function was applied to detect the breathing signal within an image stream. Respiration was successfully monitored based on a 0.3°C to 0.5°C temperature difference between the inspiration and expiration phases. Conclusions Although this method has been applied to adults before, this is the first time it was used in a newborn infant population inside the neonatal intensive care unit (NICU. The promising results suggest to include this technology into advanced NICU monitors.

  13. Neonatal non-contact respiratory monitoring based on real-time infrared thermography

    Science.gov (United States)

    2011-01-01

    Background Monitoring of vital parameters is an important topic in neonatal daily care. Progress in computational intelligence and medical sensors has facilitated the development of smart bedside monitors that can integrate multiple parameters into a single monitoring system. This paper describes non-contact monitoring of neonatal vital signals based on infrared thermography as a new biomedical engineering application. One signal of clinical interest is the spontaneous respiration rate of the neonate. It will be shown that the respiration rate of neonates can be monitored based on analysis of the anterior naris (nostrils) temperature profile associated with the inspiration and expiration phases successively. Objective The aim of this study is to develop and investigate a new non-contact respiration monitoring modality for neonatal intensive care unit (NICU) using infrared thermography imaging. This development includes subsequent image processing (region of interest (ROI) detection) and optimization. Moreover, it includes further optimization of this non-contact respiration monitoring to be considered as physiological measurement inside NICU wards. Results Continuous wavelet transformation based on Debauches wavelet function was applied to detect the breathing signal within an image stream. Respiration was successfully monitored based on a 0.3°C to 0.5°C temperature difference between the inspiration and expiration phases. Conclusions Although this method has been applied to adults before, this is the first time it was used in a newborn infant population inside the neonatal intensive care unit (NICU). The promising results suggest to include this technology into advanced NICU monitors. PMID:22243660

  14. Controlled release of betamethasone from vitamin E-loaded silicone-based soft contact lenses.

    Science.gov (United States)

    Rad, Maryam Shayani; Sajadi Tabassi, Sayyed Abolghasem; Moghadam, Maryam Hassanpour; Mohajeri, Seyed Ahmad

    2016-11-01

    Betamethasone (BMZ) is an effective drug which is commonly used as an eye drop for the management of ophthalmic inflammations. Due to low ocular bioavailability, it is necessary to prepare and optimize an ocular drug delivery system for BMZ. In this study we tried to use vitamin E diffusion barrier for sustaining BMZ release. Three commercial contact lenses were soaked in vitamin E solutions and swelling percentage, diameter, transmittance, binding capacity and release amount and time were evaluated in comparison with non-vitamin E-loaded pure lenses. The results showed that vitamin E significantly decreased water content of contact lenses whereas, increased the lens diameter in both dry and wet states. It effectively blocked UV radiation which is harmful for the eye surface while had no significant effect on visible transmittance. BMZ loading capacity enhanced and release rate remarkably decreased after using vitamin E as a hydrophobic diffusion barrier. This study revealed that vitamin E can be applied as a hydrophobic diffusion barrier for controlling and sustaining BMZ release from silicone-based soft contact lenses into the lachrymal fluid. It can also protect eye tissues as an antioxidant by blocking the UV radiation.

  15. Effective contact resistance of zinc-tin oxide-based thin film transistors.

    Science.gov (United States)

    Kang, Youjin; Han, Dongsuk; Park, Jaehyung; Shin, Sora; Choi, Duckkyun; Park, Jongwan

    2014-11-01

    We investigated different source/drain (S/D) electrode materials in thin-film transistors (TFTs) based on amorphous zinc-tin oxide (ZTO) semiconductors. The transfer length, channel conductance, and effective contact resistance between the S/D electrodes and the a-ZTO channel layer were examined. Total ON resistance (R(T)), transfer length (L(T)) and effective contact resistance (R(c-eff)) were extracted by the well-known transmission-line method (TLM) using a series of TFTs with different channel lengths. When the width of ZTO channel layer was fixed as 50 μm, the lengths were varying from 10 to 50 μm. The channel layer and S/D electrode were defined by lift-off process and for the S/D electrodes, indium-tin oxide (ITO), Cu, and Mo were used. The resistivity and work function values of electrode materials were considered when selected as candidates for S/D electrodes of ZTO-TFTs. The results showed that the ZTO-TFTs with Mo S/D electrodes had the lowest effective contact resistance indicating that ZTO-TFTs with Mo electrodes have better electrical performance compared to others.

  16. Experimental OAI-Based Digital Library Systems

    Science.gov (United States)

    Nelson, Michael L. (Editor); Maly, Kurt (Editor); Zubair, Mohammad (Editor); Rusch-Feja, Diann (Editor)

    2002-01-01

    The objective of Open Archives Initiative (OAI) is to develop a simple, lightweight framework to facilitate the discovery of content in distributed archives (http://www.openarchives.org). The focus of the workshop held at the 5th European Conference on Research and Advanced Technology for Digital Libraries (ECDL 2001) was to bring researchers in the area of digital libraries who are building OAI based systems so as to share their experiences, problems they are facing, and approaches they are taking to address them. The workshop consisted of invited talks from well-established researchers working in building OAI based digital library system along with short paper presentations.

  17. Real-time detection of respiration rate with non-contact mode based on low-end imaging equipment

    Science.gov (United States)

    Jin, Xiaoli; Dong, Liquan; Zhao, Yuejin; Liu, Xiaohua; Liu, Ming; Yang, Lei; Liu, Weiyu; Zhao, Jingsheng; Xing, Jinhui

    2013-09-01

    Standard instrumentation for the assessment of respiration rate is large and based on invasive method, and not suitable for daily inspection. An optical, simple and non-contact measurement method to detect human respiration rate using lowend imaging equipment is discussed. This technology is based on the visible light absorption of blood, which contains many important physiological information of the cardiovascular system. The light absorption of facial area can be indirectly reflected to gray value of the corresponding area image. In this paper, we acquire the respiration rate through the video signal captured by low-end imaging equipment. Firstly, the color CCD captures the facial area below the eyes and every frame of the video can be separated into three RGB channels. The blue channel is extracted as the research object. Then, we calculate the mean gray value for each image and draw the mean gray curve along the time. Fourier transform can get the frequency spectrogram of the graph, which is filtered through the Fourier filter. The extreme point is the value of the respiratory rate. Finally, an available interface program is designed and we have some volunteers tested. The correlation coefficient between the experimental data and the data provided by a reference instrument is 0.98. The consistency of the experimental results is very well. This technology costs so low that it will be widely used in medical and daily respiration rate measurement.

  18. CONSRANK: a server for the analysis, comparison and ranking of docking models based on inter-residue contacts

    KAUST Repository

    Chermak, Edrisse

    2014-12-21

    Summary: Herein, we present CONSRANK, a web tool for analyzing, comparing and ranking protein–protein and protein–nucleic acid docking models, based on the conservation of inter-residue contacts and its visualization in 2D and 3D interactive contact maps.

  19. Deproteinized bovine bone mineral particles and osseointegration of implants without primary bone contact: an experimental study in dogs.

    Science.gov (United States)

    Sivolella, Stefano; Bressan, Eriberto; Salata, Luiz A; Quiñones, Maria E; Lang, Niklaus P; Botticelli, Daniele

    2014-03-01

    To evaluate the influence on osseointegration of Deproteinized bovine bone mineral (DBBM) particles used to fill defects of at least 1 mm around implants having no primary contact with bone. Premolars and first molars were extracted bilaterally from the mandible of six Labrador dogs. After 3 months of healing, mucoperiosteal full-thickness flaps were elevated, and one recipient site was prepared in the molar region of each hemi-mandible to place implants. These were installed with a deliberate circumferential and periapical space to the bone walls of 1.2 mm. All implants were stabilized with passive fixation plates to maintain the implants in situ and without any contact with the implant bed. The control sites were left to be filled with coagulum, while at the test sites, the residual gap was filled with DBBM. After 3 months of submerged healing, the animals were sacrificed. Ground sections were prepared and analyzed histomorphometrically. Mineralized bone-to-implant contact was 4.0% and 3.9% for control and test sites, respectively. The width of the residual defects was 0.48 mm and 0.88 mm at the control and test sites, respectively. The percentage of implant surface covered by a layer of dense connective tissue of 0.12 mm of width on average was 84.9% and 88.5% at the control and test sites, respectively. A minor and not predictable degree of contact or distance osteogenesis was obtained on the implant surface when primary contact of the implant surface with the implant bed had deliberately been avoided. DBBM grafting of the artificial gap did not favor osseointegration. Neither did it enhance the ability to bridge the gap with newly formed bone in an artificial defect wider than 1 mm. © 2013 John Wiley & Sons A/S. Published by Blackwell Publishing Ltd.

  20. Non-contact metrology of aspheric surfaces based on MWLI technology

    Science.gov (United States)

    Berger, G.; Petter, J.

    2013-09-01

    A non-contact optical scanning metrology solution measuring aspheric surfaces is presented, which is based on multi wavelength interferometry (MWLI). The technology yields high density 3D data in short measurement times (including set up time) and provides high, reproducible form measurement accuracy. It measures any asphere without restrictions in terms of spherical departures. In addition, measurement of a large variety of special optics is enabled, such as annular lenses, segmented optics, optics with diffractive steps, ground optics, optics made of opaque and transparent materials, and small and thin optics (e.g. smart phone lenses). The measurement instrument can be used under production conditions.

  1. Body contact and body language

    DEFF Research Database (Denmark)

    Winther, Helle

    2008-01-01

    Body contact and body language are unique and existential and, although culturally dependent and socially embodied, they are also universal communication forms. For small children all over the world, warm, close and nourishing body contact is fundamental to their embodied experi­ence of themselves...... and the boundaries between self and world. In western societies, the modern premises for contact are in some ways developing from close contact to virtual communication. With this breadth of perspective in mind, the ques­tion is whether conscious and experimental work with body contact and body language in move......­ment psychology and education provide potential for intense personal develop­ment as well as for social and cultural learning processes. This performative research project originates from the research project entitled, Movement Psy­chol­ogy: The Language of the Body and the Psy­chol­ogy of Movement based...

  2. Experimental and Numerical Simulation of Wheel-Rail Adhesion and Wear Using a Scaled Roller Rig and a Real-Time Contact Code

    Directory of Open Access Journals (Sweden)

    Nicola Bosso

    2014-01-01

    Full Text Available The work shows the use of a scaled roller rig to validate a real time wheel-rail contact code developed to study the wheel rail adhesion and the wear evolution. The code allows the profiles to change at each time step in order to take into account the material loss due to the wear process. The contact code replicates a testing machine composed of a roller rig with a prototype of a single suspended wheelset pressed onto it with a variable load. The roller rig, developed at Politecnico di Torino, is used to validate and optimize the contact code referring to experimental data directly measured in real time. The test bench, in fact, allows measurement of specific kinematical quantities and forces that are elaborated by the real-time code in order to produce numerical results for comparison with the experimental ones. This approach can be applied both to the determination of wheel-rail adhesion and to the wear process. The test rig is also equipped with a laser profilometer that allows measurement of the wheel and rail profiles with a very high accuracy.

  3. Non-thermal alloyed ohmic contact process of GaN-based HEMTs by pulsed laser annealing

    Science.gov (United States)

    Tzou, An-Jye; Hsieh, Dan-Hua; Chen, Szu-Hung; Li, Zhen-Yu; Chang, Chun-Yen; Kuo, Hao-Chung

    2016-05-01

    We have demonstrated Si implantation incorporation into GaN HEMTs with a non-alloyed ohmic contact process. We optimized the power density of pulsed laser annealing to activate implanted Si dopants without a thermal metallization process. The experimental results show that the GaN surface will be reformed under the high power density of the illumination conditions. It provides a smooth surface for following contact engineering and leads to comparable contact resistance. The transmission line model (TLM) measurement shows a lower contact resistance to 6.8 × 10-7 Ω · cm2 via non-alloyed contact technology with significantly improved surface morphology of the contact metals. DC measurement of HEMTs shows better current and on-resistance. The on-resistance could be decreased from 2.18 to 1.74 mΩ-cm2 as we produce a lower contact resistance. Pulsed laser annealing also results in lower gate leakage and smaller dispersion under a pulse I-V measurement, which implies that the density of the surface state is improved.

  4. Silicone-Based Adhesives with Highly Tunable Adhesion Force for Skin-Contact Applications.

    Science.gov (United States)

    Lee, Bong Kuk; Ryu, Jin Hwa; Baek, In-Bok; Kim, Yarkyeon; Jang, Won Ick; Kim, Sang-Hyeob; Yoon, Yong Sun; Kim, Seung Hwan; Hong, Seong-Gu; Byun, Sangwon; Yu, Han Young

    2017-11-01

    A fundamental approach to fabricating silicone-based adhesives with highly tunable adhesion force for the skin-contact applications is presented. Liquid blends consisting of vinyl-multifunctional polydimethylsiloxane (V-PDMS), hydride-terminated PDMS (H-PDMS), and a tackifier composed of a silanol-terminated PDMS/MQ resin mixture and the MQ resin are used as the adhesive materials. The peel adhesion force of addition-cured adhesives on the skin is increased by increasing the H-PDMS molecular weights and the tackifier content, and decreasing the H-PDMS/V-PDMS ratio. There is an inverse relationship between the adhesion force and the Young's modulus. The low-modulus adhesives with a low H-PDMS/V-PDMS ratio exhibit enhanced adhesion properties. The low-modulus adhesives with the high MQ resin content show significantly enhanced adhesion properties. These adhesives exhibit a wide range of modulus (2-499 kPa), and their adhesion force (0.04-5.38 N) is superior to commercially available soft silicone adhesives (0.82-2.79 N). The strong adhesives (>≈2 N) provide sufficient adhesion for fixing the flexible electrocardiogram (ECG) device to the skin in most daily activity. The human ECG signals are successfully recorded in real time. These results suggest that the silicone-based adhesives should be useful as an atraumatic adhesive for the skin-contact applications. © 2017 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Phonon Transport through Nanoscale Contact in Tip-Based Thermal Analysis of Nanomaterials.

    Science.gov (United States)

    Dulhani, Jay; Lee, Bong Jae

    2017-07-28

    Nanomaterials have been actively employed in various applications for energy and sustainability, such as biosensing, gas sensing, solar thermal energy conversion, passive radiative cooling, etc. Understanding thermal transports inside such nanomaterials is crucial for optimizing their performance for different applications. In order to probe the thermal transport inside nanomaterials or nanostructures, tip-based nanoscale thermometry has often been employed. It has been well known that phonon transport in nanometer scale is fundamentally different from that occurred in macroscale. Therefore, Fourier's law that relies on the diffusion approximation is not ideally suitable for describing the phonon transport occurred in nanostructures and/or through nanoscale contact. In the present study, the gray Boltzmann transport equation (BTE) is numerically solved using finite volume method. Based on the gray BTE, phonon transport through the constriction formed by a probe itself as well as the nanoscale contact between the probe tip and the specimen is investigated. The interaction of a probe and a specimen (i.e., treated as a substrate) is explored qualitatively by analyzing the temperature variation in the tip-substrate configuration. Besides, each contribution of a probe tip, tip-substrate interface, and a substrate to the thermal resistance are analyzed for wide ranges of the constriction ratio of the probe.

  6. Epidemic Spreading Characteristics and Immunity Measures Based on Complex Network with Contact Strength and Community Structure

    Directory of Open Access Journals (Sweden)

    Xueting Zhang

    2015-01-01

    Full Text Available Middle East Respiratory Syndrome (MERS, bursting in South Korea from May 2015 and mainly spreading within the hospitals at the beginning, has caused a large scale of public panic. Aiming at this kind of epidemic spreading swiftly by intimate contact within community structure, we first established a spreading model based on contact strength and SI model, and a weighted network with community structure based on BBV network model. Meanwhile, the sufficient conditions were deduced to ensure the optimal community division. Next, after the verification by the real data of MERS, it is found that the spreading rate is closely related to the average weight of network but not the number of communities. Then, as the further study shows, the final infection proportion declines with the decreases both in isolation delay and in average weight; however, this proportion can only be postponed rather than decreased with respect to sole average weight reduction without isolation. Finally, the opportunities to take action can be found to restrain the epidemic spreading to the most extent.

  7. Adaptive local surface refinement based on LR NURBS and its application to contact

    Science.gov (United States)

    Zimmermann, Christopher; Sauer, Roger A.

    2017-12-01

    A novel adaptive local surface refinement technique based on Locally Refined Non-Uniform Rational B-Splines (LR NURBS) is presented. LR NURBS can model complex geometries exactly and are the rational extension of LR B-splines. The local representation of the parameter space overcomes the drawback of non-existent local refinement in standard NURBS-based isogeometric analysis. For a convenient embedding into general finite element codes, the Bézier extraction operator for LR NURBS is formulated. An automatic remeshing technique is presented that allows adaptive local refinement and coarsening of LR NURBS. In this work, LR NURBS are applied to contact computations of 3D solids and membranes. For solids, LR NURBS-enriched finite elements are used to discretize the contact surfaces with LR NURBS finite elements, while the rest of the body is discretized by linear Lagrange finite elements. For membranes, the entire surface is discretized by LR NURBS. Various numerical examples are shown, and they demonstrate the benefit of using LR NURBS: Compared to uniform refinement, LR NURBS can achieve high accuracy at lower computational cost.

  8. Contact-based ligand-clustering approach for the identification of active compounds in virtual screening

    Directory of Open Access Journals (Sweden)

    Mantsyzov AB

    2012-09-01

    Full Text Available Alexey B Mantsyzov,1 Guillaume Bouvier,2 Nathalie Evrard-Todeschi,1 Gildas Bertho11Université Paris Descartes, Sorbonne, Paris, France; 2Institut Pasteur, Paris, FranceAbstract: Evaluation of docking results is one of the most important problems for virtual screening and in silico drug design. Modern approaches for the identification of active compounds in a large data set of docked molecules use energy scoring functions. One of the general and most significant limitations of these methods relates to inaccurate binding energy estimation, which results in false scoring of docked compounds. Automatic analysis of poses using self-organizing maps (AuPosSOM represents an alternative approach for the evaluation of docking results based on the clustering of compounds by the similarity of their contacts with the receptor. A scoring function was developed for the identification of the active compounds in the AuPosSOM clustered dataset. In addition, the AuPosSOM efficiency for the clustering of compounds and the identification of key contacts considered as important for its activity, were also improved. Benchmark tests for several targets revealed that together with the developed scoring function, AuPosSOM represents a good alternative to the energy-based scoring functions for the evaluation of docking results.Keywords: scoring, docking, virtual screening, CAR, AuPosSOM

  9. Novel application of bamboo-based fibers in a biological contact oxidation process.

    Science.gov (United States)

    Zou, Xiaoming; Feng, Yi; Sheng, Changming; Liu, Jia; Lu, Lijun; Hu, Cui; Huang, Xiangfeng

    2014-01-01

    Generally, biofilm-supporting carriers in biological contact oxidation processes are made from thermoplastic polymers, which cause potential ecological damage because of the low biodegradation and high accumulation in organisms. Thus, four bamboo-based fibers, bamboo primitive fiber, bamboo fiber, bamboo charcoal fiber (BBF) and bamboo charcoal-cotton blending fiber (BCBF), were used as carriers and compared with two commercial carriers (vinylon (VY) and polypropylene (PP)) in a biological contact oxidation process system with the goal to develop a biodegradable and sustainable biofilm medium. Under steady state conditions, pollutants (chemical oxygen demand and NH4(+)-N) in stage 1 (days 1-29, hydraulic retention time (HRT) = 12 h) were efficiently removed with a removal efficiency ranging from 85 to 95%. In stage 2 (days 30-53, HRT = 4-12 h), the pollutant-removal efficiency of four reactors (BBF, BCBF, VY and PP) were nearly indistinguishable and were higher than the two other reactors, especially when the HRT was set at 4 h (days 46-53). Consequently, two optimized bamboo-based fibers (BBF and BCBF) can be developed as biofilm carriers for wastewater treatment in the future. Furthermore, studies demonstrated that the biofilm development difference showed good correlation with their specific area and relative oxygen content but not with their tenacity and antimicrobial activity.

  10. Educational Intervention for an Evidence-Based Nursing Practice of Skin-to-Skin Contact at Birth

    Science.gov (United States)

    Turenne, Jeanne Pigeon; Héon, Marjolaine; Aita, Marilyn; Faessler, Joanne; Doddridge, Chantal

    2016-01-01

    ABSTRACT This article presents the development and evaluation of an educational intervention aiming at an evidence-based practice of skin-to-skin contact at birth among nurses of a maternity care unit. Based on the Iowa Model of Evidence-Based Practice to Promote Quality Care, four educational sessions were developed according to an active-learning pedagogy. Even if the nurses’ practice did not fully meet the recommendations for skin-to-skin contact, a pre- and postintervention evaluation showed some positive results, such as a longer duration of skin-to-skin contact immediately after birth, delivery of some routine care directly on mothers’ chest, and improved parent education. The educational intervention seems to have enacted some evidence-based nursing practice changes regarding skin-to-skin contact at birth. PMID:27445449

  11. Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array

    OpenAIRE

    Navruz, Isa; Coskun, Ahmet F.; Wong, Justin; Mohammad, Saqib; Tseng, Derek; Nagi, Richie; Phillips, Stephen; Ozcan, Aydogan

    2013-01-01

    We demonstrate a cellphone based contact microscopy platform, termed Contact Scope, which can image highly dense or connected samples in transmission mode. Weighing approximately 76 grams, this portable and compact microscope is installed on the existing camera unit of a cellphone using an opto-mechanical add-on, where planar samples of interest are placed in contact with the top facet of a tapered fiber-optic array. This glass-based tapered fiber array has ∼9 fold higher density of fiber opt...

  12. Robust thin-film generator based on segmented contact-electrification for harvesting wind energy.

    Science.gov (United States)

    Meng, Xian Song; Zhu, Guang; Wang, Zhong Lin

    2014-06-11

    Collecting and converting energy from ambient air flow promise to be a viable approach in developing self-powered autonomous electronics. Here, we report an effective and robust triboelectric generator that consists of an undulating thin-film membrane and an array of segmented fine-sized electrode pairs on a single substrate. Sequential processes of contact electrification and electrostatic induction generate alternating flows of free electrons when the membrane interacts with ambient air flow. Based on an optimum rational design, the segmented electrodes play an essential role in boosting the output current, leading to an enhancement of over 500% compared to the structure without the segmentation. The thin-film based generator can simultaneously and continuously light up tens of commercial light-emitting diodes. Moreover, it possesses exceptional durability, providing constant electric output after millions of operation cycles. This work offers a truly practical solution that opens the avenue to take advantage of wind energy by using the triboelectric effect.

  13. Non-Invasive monitoring of diaphragmatic timing by means of surface contact sensors: An experimental study in dogs

    Directory of Open Access Journals (Sweden)

    Galdiz Batxi

    2004-09-01

    Full Text Available Abstract Background Non-invasive monitoring of respiratory muscle function is an area of increasing research interest, resulting in the appearance of new monitoring devices, one of these being piezoelectric contact sensors. The present study was designed to test whether the use of piezoelectric contact (non-invasive sensors could be useful in respiratory monitoring, in particular in measuring the timing of diaphragmatic contraction. Methods Experiments were performed in an animal model: three pentobarbital anesthetized mongrel dogs. The motion of the thoracic cage was acquired by means of a piezoelectric contact sensor placed on the costal wall. This signal is compared with direct measurements of the diaphragmatic muscle length, made by sonomicrometry. Furthermore, to assess the diaphragmatic function other respiratory signals were acquired: respiratory airflow and transdiaphragmatic pressure. Diaphragm contraction time was estimated with these four signals. Using diaphragm length signal as reference, contraction times estimated with the other three signals were compared with the contraction time estimated with diaphragm length signal. Results The contraction time estimated with the TM signal tends to give a reading 0.06 seconds lower than the measure made with the DL signal (-0.21 and 0.00 for FL and DP signals, respectively, with a standard deviation of 0.05 seconds (0.08 and 0.06 for FL and DP signals, respectively. Correlation coefficients indicated a close link between time contraction estimated with TM signal and contraction time estimated with DL signal (a Pearson correlation coefficient of 0.98, a reliability coefficient of 0.95, a slope of 1.01 and a Spearman's rank-order coefficient of 0.98. In general, correlation coefficients and mean and standard deviation of the difference were better in the inspiratory load respiratory test than in spontaneous ventilation tests. Conclusion The technique presented in this work provides a non

  14. Effects of contact-based mental illness stigma reduction programs: age, gender, and Asian, Latino, and White American differences.

    Science.gov (United States)

    Wong, Eunice C; Collins, Rebecca L; Cerully, Jennifer L; Yu, Jennifer W; Seelam, Rachana

    2017-12-02

    Mental illness stigma disproportionately affects help seeking among youth, men, and ethnic minorities. As part of a comprehensive statewide initiative to reduce mental illness stigma and discrimination in California, a broad set of contact-based educational programs were widely disseminated. This study examined whether the effects of contact-based educational programs varied depending on the age, gender, and race-ethnicity of participants. Participants (N = 4122) attended a contact-based educational program that was delivered as part of the statewide initiative to reduce mental illness stigma and discrimination. Self-administered surveys assessing beliefs, attitudes, and intentions toward mental illnesses and treatment were conducted immediately before and after participation in contact-based educational programs. Participant age, gender, and race-ethnicity significantly moderated pre-post changes in mental illness stigma. Although all groups exhibited significant pre-post changes across most of the stigma domains assessed, young adults, females, and Asian and Latino American participants reported larger improvements compared to older adults, males, and Whites, respectively. Findings suggest that contact-based educational programs can achieve immediate reductions in mental illness stigma across a variety of sociodemographic groups and may particularly benefit young adults and racial-ethnic minorities. Further research is needed to assess whether contact-based educational programs can sustain longer-term changes and aid in the reduction of disparities in mental illness stigma and treatment.

  15. Binding Direction-Based Two-Dimensional Flattened Contact Area Computing Algorithm for Protein–Protein Interactions

    Directory of Open Access Journals (Sweden)

    Beom Sik Kang

    2017-10-01

    Full Text Available Interactions between protein molecules are essential for the assembly, function, and regulation of proteins. The contact region between two protein molecules in a protein complex is usually complementary in shape for both molecules and the area of the contact region can be used to estimate the binding strength between two molecules. Although the area is a value calculated from the three-dimensional surface, it cannot represent the three-dimensional shape of the surface. Therefore, we propose an original concept of two-dimensional contact area which provides further information such as the ruggedness of the contact region. We present a novel algorithm for calculating the binding direction between two molecules in a protein complex, and then suggest a method to compute the two-dimensional flattened area of the contact region between two molecules based on the binding direction.

  16. Development and testing of new biologically-based polymers as advanced biocompatible contact lenses

    Energy Technology Data Exchange (ETDEWEB)

    Bertozzi, Carolyn R.

    2000-06-01

    Nature has evolved complex and elegant materials well suited to fulfill a myriad of functions. Lubricants, structural scaffolds and protective sheaths can all be found in nature, and these provide a rich source of inspiration for the rational design of materials for biomedical applications. Many biological materials are based in some fashion on hydrogels, the crosslinked polymers that absorb and hold water. Biological hydrogels contribute to processes as diverse as mineral nucleation during bone growth and protection and hydration of the cell surface. The carbohydrate layer that coats all living cells, often referred to as the glycocalyx, has hydrogel-like properties that keep cell surfaces well hydrated, segregated from neighboring cells, and resistant to non-specific protein deposition. With the molecular details of cell surface carbohydrates now in hand, adaptation of these structural motifs to synthetic materials is an appealing strategy for improving biocompatibility. The goal of this collaborative project between Prof. Bertozzi's research group, the Center for Advanced Materials at Lawrence Berkeley National Laboratory and Sunsoft Corporation was the design, synthesis and characterization of novel hydrogel polymers for improved soft contact lens materials. Our efforts were motivated by the urgent need for improved materials that allow extended wear, and essential feature for those whose occupation requires the use of contact lenses rather than traditional spectacles. Our strategy was to transplant the chemical features of cell surface molecules into contact lens materials so that they more closely resemble the tissue in which they reside. Specifically, we integrated carbohydrate molecules similar to those found on cell surfaces, and sulfoxide materials inspired by the properties of the carbohydrates, into hydrogels composed of biocompatible and manufacturable substrates. The new materials were characterized with respect to surface and bulk hydrophilicity

  17. Dynamic fatigue reliability of contact wires based on dynamic simulation of high-speed pantograph-catenary

    Science.gov (United States)

    Hu, Ping; Liang, Jie; Fan, Wenli

    2017-05-01

    This paper proposed a dynamic fatigue reliability method of contact wires based on dynamic simulation of high-speed pantograph-catenary. Firstly, the Weibull distribution was adopted to describe the fatigue life of contact wires so as to build the fatigue reliability model of contact wires. And then 10 finite element models of elastic chain type for contact networks were set up with the EN50367 parameter. Thereafter the stress time of the weakest unit on contact wires was calculated through the finite element simulation. Secondly, the mean value and amplitude of each stress cycle were calculated by means of rain flow counting method, and these values were put into the reliability model to draw the changing curve of the fatigue reliability of contact wires with time. The numerical example showed that the fatigue reliability of contact wires would be less than 0.98 when these wires were used for more than 10 years. The method provided in this paper can be used to estimate the fatigue reliability of contact wires more accurately, and it can be used as a reference for the reliability design of the catenary system and the formulation of preventive maintenance plans.

  18. Volumetric quantification of bone-implant contact using micro-computed tomography analysis based on region-based segmentation

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Sung Won; Lee, Woo Jin; Choi, Soon Chul; Lee, Sam Sun; Heo, Min Suk; Huh, Kyung Hoe; Kim, Tae Il; Yi, Won Ji [Dental Research Institute, School of Dentistry, Seoul National University, Seoul (Korea, Republic of)

    2015-03-15

    We have developed a new method of segmenting the areas of absorbable implants and bone using region-based segmentation of micro-computed tomography (micro-CT) images, which allowed us to quantify volumetric bone-implant contact (VBIC) and volumetric absorption (VA). The simple threshold technique generally used in micro-CT analysis cannot be used to segment the areas of absorbable implants and bone. Instead, a region-based segmentation method, a region-labeling method, and subsequent morphological operations were successively applied to micro-CT images. The three-dimensional VBIC and VA of the absorbable implant were then calculated over the entire volume of the implant. Two-dimensional (2D) bone-implant contact (BIC) and bone area (BA) were also measured based on the conventional histomorphometric method. VA and VBIC increased significantly with as the healing period increased (p<0.05). VBIC values were significantly correlated with VA values (p<0.05) and with 2D BIC values (p<0.05). It is possible to quantify VBIC and VA for absorbable implants using micro-CT analysis using a region-based segmentation method.

  19. Estudio experimental sobre el comportamiento del hierro austemperado nitrurado (adi a la fatiga de contacto. // Experimental study to contact fatigue behavior of nitrided-austempered ductile iron.

    Directory of Open Access Journals (Sweden)

    C. Figueroa

    2001-10-01

    Full Text Available En el presente trabajo se muestra un estudio sobre el hierro fundido austemperado nitrurado sometido a pruebas de fatiga decontacto. El mismo se austenitizó y austemperó a las temperaturas de 900 y 3800C respectivamente, seleccionándose enambos casos un tiempo de 2 horas. Después se le aplicó un proceso de nitruración gaseosa a 5700C durante 6 horas.Las experiencias fueron realizadas en una máquina para el ensayo de fatiga de contacto con discos. Las presionesHertzianas utilizadas fueron de 1.73, 1.78, 2.04, 2.41, 2.46 y 2.71 GPa.La composición de fases se determinó utilizando la difracción de rayos X, evidenciándose la presencia de los compuestos e(Fe2-3N y g¢ (Fe4N. Los defectos tales como: pittings spalls y grietas fueron observados por medio de la microscopíaelectrónica de barrido (SEM. Los resultados indicaron que la capa nitrurada entre 5 y 6 micras de espesor desaparece bajola acción de las presiones de contacto. Por otra parte se pudo detectar una disminución de la resistencia a la fatiga en el ADInitrurado cuando fueron utilizadas bajas presiones Hertzianas También se comprobó que los nódulos de grafito actúancomo barreras a la propagación de grietas.Palabras claves: Fatiga de contacto, Capa nitrurada, hierro dúctil austemperado, máquina de fatiga condiscos, rayos X._____________________________________________________________________AbstractThis paper presents a study on the behavior of nitrided austempered ductile iron (ADI under contact fatigue tests. ADI wasaustenitized at 9000C for 2 hours and austempered at 380oC for 2 hours. Later, the ADI was nitrided at 570oC for a periodof 6 hours.The contact fatigue tests were carried out using a disc test machine. Hertzian pressures of 1.73, 1.78, 2.04, 2.41, 2.46 and2.71 were used during the tests.The phase composition of nitride layer was determined using X-ray analysis, which detected the presence of the e and g¢phases. The pitting, spalls and cracks that appeared

  20. Physical Non-Contact Communication between Microscopic Aquatic Species: Novel Experimental Evidences for an Interspecies Information Exchange

    Directory of Open Access Journals (Sweden)

    Daniel Fels

    2016-01-01

    Full Text Available Previous experiments on physical non-contact communication within same species gave rise to test for this type of communication also across the species border, which was the aim of the present study. It was found that autotrophic unicellular organisms (Euglena viridis, separated by cuvettes, affected the proliferation rate of heterotrophic unicellular organisms (Paramecium caudatum. Further, the heterotrophic unicellular organism affected also the proliferation rate of a multicellular heterotrophic organism (Rotatoria sp. and vice versa. In the case when populations (of Euglena viridis and Paramecium caudatum were shielded against electromagnetic fields in the optical spectrum from each other, no effects were measured. The results may support the notion that the organisation of ecosystems relies also on the exchange of electromagnetic fields from their constituting biosystems.

  1. Physical Non-Contact Communication between Microscopic Aquatic Species: Novel Experimental Evidences for an Interspecies Information Exchange.

    Science.gov (United States)

    Fels, Daniel

    2016-01-01

    Previous experiments on physical non-contact communication within same species gave rise to test for this type of communication also across the species border, which was the aim of the present study. It was found that autotrophic unicellular organisms (Euglena viridis), separated by cuvettes, affected the proliferation rate of heterotrophic unicellular organisms (Paramecium caudatum). Further, the heterotrophic unicellular organism affected also the proliferation rate of a multicellular heterotrophic organism (Rotatoria sp.) and vice versa. In the case when populations (of Euglena viridis and Paramecium caudatum) were shielded against electromagnetic fields in the optical spectrum from each other, no effects were measured. The results may support the notion that the organisation of ecosystems relies also on the exchange of electromagnetic fields from their constituting biosystems.

  2. Experimental study of bone response to hydroxyapatite coating implants: bone-implant contact and removal torque test.

    Science.gov (United States)

    Eom, Tae-Gwan; Jeon, Gyeo-Rok; Jeong, Chang-Mo; Kim, Young-Kyun; Kim, Su-Gwan; Cho, In-Hee; Cho, Yong-Seok; Oh, Ji-Su

    2012-10-01

    The objective of this study was to evaluate the early osseointegration of hydroxyapatite (HA)-coated implant. Twelve adult male miniature pigs were used in this study. The removal torque of implants placed in the tibia of miniature pigs was measured. For implants placed in the mandible, histomorphometric evaluation was performed for the evaluation of the bone-implant contact (BIC) ratio. After 4, 8, and 12 weeks, removal torque values were increased. Among the 3 groups, the HA-coated group showed the highest values (P < .05). At 4 and 8 weeks, the BIC ratio of HA was significantly higher than that of resorbable blast medium or sand blasted with alumina and acid etched (P < .05). It was concluded that HA-coated implants are relatively favorable in early loading stages. Copyright © 2012 Elsevier Inc. All rights reserved.

  3. Using a consensus approach based on the conservation of inter-residue contacts to rank CAPRI models

    KAUST Repository

    Vangone, Anna

    2013-10-17

    Herein we propose the use of a consensus approach, CONSRANK, for ranking CAPRI models. CONSRANK relies on the conservation of inter-residue contacts in the analyzed decoys ensemble. Models are ranked according to their ability to match the most frequently observed contacts. We applied CONSRANK to 19 CAPRI protein-protein targets, covering a wide range of prediction difficulty and involved in a variety of biological functions. CONSRANK results are consistently good, both in terms of native-like (NL) solutions ranked in the top positions and of values of the Area Under the receiver operating characteristic Curve (AUC). For targets having a percentage of NL solutions above 3%, an excellent performance is found, with AUC values approaching 1. For the difficult target T46, having only 3.4% NL solutions, the number of NL solutions in the top 5 and 10 ranked positions is enriched by a factor 30, and the AUC value is as high as 0.997. AUC values below 0.8 are only found for targets featuring a percentage of NL solutions within 1.1%. Remarkably, a false consensus emerges only in one case, T42, which happens to be an artificial protein, whose assembly details remain uncertain, based on controversial experimental data. We also show that CONSRANK still performs very well on a limited number of models, provided that more than 1 NL solution is included in the ensemble, thus extending its applicability to cases where few dozens of models are available.© 2013 Wiley Periodicals, Inc.

  4. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, K E

    2003-01-01

    meter. 3 of 15 hand eczema patients developed eczema on the finger immersed in the fragrance-containing solution, 3 of 15 on the placebo finger and 3 of 15 on both fingers. Using this experimental exposure model simulating real-life exposure, we found no association between immersion of a finger...

  5. A socially aware routing based on local contact information in delay-tolerant networks.

    Science.gov (United States)

    Kim, Chan-Myung; Han, Youn-Hee; Youn, Joo-Sang; Jeong, Young-Sik

    2014-01-01

    In delay-tolerant networks, network topology changes dynamically and there is no guarantee of continuous connectivity between any two nodes. These features make DTN routing one of important research issues, and the application of social network metrics has led to the design of recent DTN routing schemes. In this paper, we propose an efficient routing scheme by using a node's local contact history and social network metrics. Each node first chooses a proper relay node based on the closeness to the destination node. A locally computed betweenness centrality is additionally utilized to enhance the routing efficiency. Through intensive simulation, we finally demonstrate that our algorithm performs efficiently compared to the existing epidemic or friendship routing scheme.

  6. Real time optimization of solar powered direct contact membrane distillation based on multivariable extremum seeking

    KAUST Repository

    Karam, Ayman M.

    2015-09-21

    This paper presents a real time optimization scheme for a solar powered direct contact membrane distillation (DCMD) water desalination system. The sun and weather conditions vary and are inconsistent throughout the day. Therefore, the solar powered DCMD feed inlet temperature is never constant, which influences the distilled water flux. The problem of DCMD process optimization has not been studied enough. In this work, the response of the process under various feed inlet temperatures is investigated, which demonstrates the need for an optimal controller. To address this issue, we propose a multivariable Newton-based extremum seeking controller which optimizes the inlet feed and permeate mass flow rates as the feed inlet temperature varies. Results are presented and discussed for a realistic temperature profile.

  7. Cultivating healthy places and communities: evidenced-based nature contact recommendations.

    Science.gov (United States)

    Largo-Wight, Erin

    2011-02-01

    Cultivating healthful places is an important public health focus. This paper presents evidence-based recommendations related to nature contact. A multidisciplinary review was conducted in several fields of study and findings were organized into public health recommendations: (1) cultivate grounds for viewing, (2) maintain healing gardens, (3) incorporate wooded parks and green space in communities, (4) advocate for preservation of pristine wilderness, (5) welcome animals indoors, (6) provide a plethora of indoor potted plants within view, (7) light rooms with bright natural light, (8) provide a clear view of nature outside, (9) allow outside air and sounds in, (10) display nature photography and realistic nature art, (11) watch nature on TV or videos, and (12) listen to recorded sounds of nature. The findings should inform public health promoters in the design of healthy places and communities. Future research needs are highlighted.

  8. ContactLess Integrated Photonic Probe for light monitoring in InP-based devices

    CERN Document Server

    Melati, Daniele; Grillanda, Stefano; Ferrari, Giorgio; Morichetti, Francesco; Sampietro, Marco; Melloni, Andrea

    2014-01-01

    The increasing complexity of photonic integrated circuits requires the possibility to monitor the state of the circuit in order to stabilize the working point against environmental fluctuations or to perform reliable reconfiguration procedures. Although InP technologies can naturally integrate high-quality photodiodes, their use as tap monitors necessarily affects the circuit response and is restricted to few units per chip. They are hence unsuited for very large circuits, where transparent power monitors become key components. In this paper we present the implementation of a ContactLess Integrated Photonic Probe (CLIPP) realizing a non invasive integrated light monitor on InP-based devices. We describe an innovative vertical scheme of the CLIPP monitor which exploits the back side of the chip as a common electrode, thus enabling a reduction of the device footprint and a simplification of the electrical connectivity. We characterize the response of the CLIPP and demonstrate its functionality as power monitor....

  9. Greenlandic adoptees' psychiatric inpatient contact. A comparative register-based study

    DEFF Research Database (Denmark)

    Laubjerg, Merete; Petersson, Birgit

    2010-01-01

    and international research stressing that adoptees demonstrate reverse health outcomes. The cohort is in-ward patients (> 24 hours), born between 1973 and 2005. Correlation between various dependent and independent variables are analysed. The research makes different comparative statements of psychiatric admissions......  The aim is to highlight adoptees' and stepchildren's psychiatric contact and diagnoses compared to non-adoptees. The setting is Greenland and the methodology is a comparative in-ward patient register-based study. The background is the Greenlandic tradition for adoption and community child care...... and diagnoses related to adoptees and stepchildren compared to non-adoptees with respect to demographic and socio-economic indicators. The psychiatric data material is collected from 1992 to 2008 and the socio-economic indicators are included from 1996. The findings show, contrary to findings related...

  10. Detection of needle to nerve contact based on electric bioimpedance and machine learning methods.

    Science.gov (United States)

    Kalvoy, Havard; Tronstad, Christian; Ullensvang, Kyrre; Steinfeldt, Thorsten; Sauter, Axel R

    2017-07-01

    In an ongoing project for electrical impedance-based needle guidance we have previously showed in an animal model that intraneural needle positions can be detected with bioimpedance measurement. To enhance the power of this method we in this study have investigated whether an early detection of the needle only touching the nerve also is feasible. Measurement of complex impedance during needle to nerve contact was compared with needle positions in surrounding tissues in a volunteer study on 32 subjects. Classification analysis using Support-Vector Machines demonstrated that discrimination is possible, but that the sensitivity and specificity for the nerve touch algorithm not is at the same level of performance as for intra-neuralintraneural detection.

  11. Multicenter Patch Testing With a Resol Resin Based on Phenol and Formaldehyde Within the International Contact Dermatitis Research Group

    DEFF Research Database (Denmark)

    Isaksson, M.; Ale, I.; Andersen, Klaus Ejner

    2015-01-01

    Background Contact allergy to phenol-formaldehyde resins (PFRs) based on phenol and formaldehyde is not detected by a p-tertiary-butylphenol-formaldehyde resin included in most baseline patch test series. Objective The aims of this study were to investigate the contact allergy rate to PFR-2.......2%) reacted to PFR-2. Of those 28 individuals, one had a positive reaction to formaldehyde and 2 to p-tertiary-butylphenol-formaldehyde resin. Simultaneous allergic reactions were noted to colophonium in 3, to Myroxylon pereirae in 5, and to fragrance mix I in 8. Conclusions The contact allergy frequency...

  12. Bagaza virus is pathogenic and transmitted by direct contact in experimentally infected partridges, but is not infectious in house sparrows and adult mice.

    Science.gov (United States)

    Llorente, Francisco; Pérez-Ramírez, Elisa; Fernández-Pinero, Jovita; Elizalde, Maia; Figuerola, Jordi; Soriguer, Ramón C; Jiménez-Clavero, Miguel Ángel

    2015-09-04

    Bagaza virus (BAGV) is a mosquito-borne flavivirus belonging to the Ntaya serocomplex. In 2010, a disease outbreak was reported in Cádiz (Southern Spain) affecting game birds (red-legged partridges and common pheasants). In this work, red-legged partridges were inoculated experimentally with infectious BAGV isolated from this outbreak in order to make a complete clinical and analytical assessment of the disease caused by the pathogen in this species. Viral load (by real-time RT-PCR) in blood, oral and cloacal swabs, and feathers, and neutralizing antibody titres (by VNT) were measured. In order to determine direct contact transmission, non-inoculated partridges were caged together with the inoculated ones. To assess infectiousness in other species, house sparrows and mice were also inoculated with the virus. All the inoculated partridges were clinically affected, and 30% of them died. All the infected individuals lost weight, with larger losses being recorded in females. Conversely, no mortality or disease symptoms were observed in the sparrows or mice. Remarkably, all the contact partridges acquired the infection by direct (non-vectored) transmission. This study confirms that the red-legged partridge is a susceptible host for BAGV infection, and that this pathogen is transmitted by direct contact. Long-lasting viral loads detected in calami of immature feathers demonstrate that feather sampling could be a useful strategy in active surveillance programs for early detection of BAGV.

  13. An Interactive Multimedia Based Instruction in Experimental Modelling

    DEFF Research Database (Denmark)

    Knudsen, Morten; Nielsen, J.N.; Østergaard, J.

    1997-01-01

    A CD-ROM based interactive multimedia instruction in experimental modelling for Danish Engineering School teachers is described. The content is based on a new sensitivity approach for direct estimation of physical parameters in linear and nonlinear dynamic systems. The presentation is inspired...

  14. Preparation of electrodes on cfrp composites with low contact resistance comprising laser-based surface pre-treatment

    KAUST Repository

    Almuhammadi, Khaled Hamdan

    2016-12-29

    Various examples are provided related to the preparation of electrodes on carbon fiber reinforced polymer (CFRP) composites with low contact resistance. Laser-based surface preparation can be used for bonding to CFRP composites. In one example, a method includes preparing a pretreated target area on a CFRP composite surface using laser pulsed irradiation and bonding an electrode to exposed fibers in the pretreated target area. The surface preparation can allow the electrode to have a low contact resistance with the CFRP composite.

  15. A Simple Approach to Characterize Gas-Aqueous Liquid Two-phase Flow Configuration Based on Discrete Solid-Liquid Contact Electrification

    Science.gov (United States)

    Choi, Dongwhi; Lee, Donghyeon; Sung Kim, Dong

    2015-10-01

    In this study, we first suggest a simple approach to characterize configuration of gas-aqueous liquid two-phase flow based on discrete solid-liquid contact electrification, which is a newly defined concept as a sequential process of solid-liquid contact and successive detachment of the contact liquid from the solid surface. This approach exhibits several advantages such as simple operation, precise measurement, and cost-effectiveness. By using electric potential that is spontaneously generated by discrete solid-liquid contact electrification, the configurations of the gas-aqueous liquid two-phase flow such as size of a gas slug and flow rate are precisely characterized. According to the experimental and numerical analyses on parameters that affect electric potential, gas slugs have been verified to behave similarly to point electric charges when the measuring point of the electric potential is far enough from the gas slug. In addition, the configuration of the gas-aqueous liquid two-phase microfluidic system with multiple gas slugs is also characterized by using the presented approach. For a proof-of-concept demonstration of using the proposed approach in a self-triggered sensor, a gas slug detector with a counter system is developed to show its practicality and applicability.

  16. Decomposition of Imidazolium-Based Ionic Liquids in Contact with Lithium Metal.

    Science.gov (United States)

    Schmitz, Paulo; Jakelski, Rene; Pyschik, Marcelina; Jalkanen, Kirsi; Nowak, Sascha; Winter, Martin; Bieker, Peter

    2017-03-09

    Ionic liquids (ILs) are considered to be suitable electrolyte components for lithium-metal batteries. Imidazolium cation based ILs were previously found to be applicable for battery systems with a lithium-metal negative electrode. However, herein it is shown that, in contrast to the well-known IL N-butyl-N-methylpyrrolidinium bis[(trifluoromethyl)sulfonyl]imide ([Pyr14 ][TFSI]), 1-ethyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide ([C2MIm][TFSI]) and 1-butyl-3-methylimidazolium bis[(trifluoromethyl)sulfonyl]imide ([C4MIm][TFSI]) are chemically unstable versus metallic lithium. A lithium-metal sheet was immersed in pure imidazolium-based IL samples and aged at 60 °C for 28 days. Afterwards, the aged IL samples were investigated to deduce possible decomposition products of the imidazolium cation. The chemical instability of the ILs in contact with lithium metal and a possible decomposition starting point are shown for the first time. Furthermore, the investigated imidazolium-based ILs can be utilized for lithium-metal batteries through the addition of the solid-electrolyte interphase (SEI) film-forming additive fluoroethylene carbonate. © 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

  17. Automatic detection of measurement points for non-contact vibrometer-based diagnosis of cardiac arrhythmias

    Science.gov (United States)

    Metzler, Jürgen; Kroschel, Kristian; Willersinn, Dieter

    2017-03-01

    Monitoring of the heart rhythm is the cornerstone of the diagnosis of cardiac arrhythmias. It is done by means of electrocardiography which relies on electrodes attached to the skin of the patient. We present a new system approach based on the so-called vibrocardiogram that allows an automatic non-contact registration of the heart rhythm. Because of the contactless principle, the technique offers potential application advantages in medical fields like emergency medicine (burn patient) or premature baby care where adhesive electrodes are not easily applicable. A laser-based, mobile, contactless vibrometer for on-site diagnostics that works with the principle of laser Doppler vibrometry allows the acquisition of vital functions in form of a vibrocardiogram. Preliminary clinical studies at the Klinikum Karlsruhe have shown that the region around the carotid artery and the chest region are appropriate therefore. However, the challenge is to find a suitable measurement point in these parts of the body that differs from person to person due to e. g. physiological properties of the skin. Therefore, we propose a new Microsoft Kinect-based approach. When a suitable measurement area on the appropriate parts of the body are detected by processing the Kinect data, the vibrometer is automatically aligned on an initial location within this area. Then, vibrocardiograms on different locations within this area are successively acquired until a sufficient measuring quality is achieved. This optimal location is found by exploiting the autocorrelation function.

  18. Efficient Regular Perovskite Solar Cells Based on Pristine [70]Fullerene as Electron-Selective Contact.

    Science.gov (United States)

    Collavini, Silvia; Kosta, Ivet; Völker, Sebastian F; Cabanero, German; Grande, Hans J; Tena-Zaera, Ramón; Delgado, Juan Luis

    2016-06-08

    [70]Fullerene is presented as an efficient alternative electron-selective contact (ESC) for regular-architecture perovskite solar cells (PSCs). A smart and simple, well-described solution processing protocol for the preparation of [70]- and [60]fullerene-based solar cells, namely the fullerene saturation approach (FSA), allowed us to obtain similar power conversion efficiencies for both fullerene materials (i.e., 10.4 and 11.4 % for [70]- and [60]fullerene-based devices, respectively). Importantly, despite the low electron mobility and significant visible-light absorption of [70]fullerene, the presented protocol allows the employment of [70]fullerene as an efficient ESC. The [70]fullerene film thickness and its solubility in the perovskite processing solutions are crucial parameters, which can be controlled by the use of this simple solution processing protocol. The damage to the [70]fullerene film through dissolution during the perovskite deposition is avoided through the saturation of the perovskite processing solution with [70]fullerene. Additionally, this fullerene-saturation strategy improves the performance of the perovskite film significantly and enhances the power conversion efficiency of solar cells based on different ESCs (i.e., [60]fullerene, [70]fullerene, and TiO2 ). Therefore, this universal solution processing protocol widens the opportunities for the further development of PSCs. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  19. Finite element based contact analysis of radio frequency MEMs switch membrane surfaces

    Science.gov (United States)

    Liu, Jin-Ya; Chalivendra, Vijaya; Huang, Wenzhen

    2017-10-01

    Finite element simulations were performed to determine the contact behavior of radio frequency (RF) micro-electro-mechanical (MEM) switch contact surfaces under monotonic and cyclic loading conditions. Atomic force microscopy (AFM) was used to capture the topography of RF-MEM switch membranes and later they were analyzed for multi-scale regular as well as fractal structures. Frictionless, non-adhesive contact 3D finite element analysis was carried out at different length scales to investigate the contact behavior of the regular-fractal surface using an elasto-plastic material model. Dominant micro-scale regular patterns were found to significantly change the contact behavior. Contact areas mainly cluster around the regular pattern. The contribution from the fractal structure is not significant. Under cyclic loading conditions, plastic deformation in the 1st loading/unloading cycle smooth the surface. The subsequent repetitive loading/unloading cycles undergo elastic contact without changing the morphology of the contacting surfaces. The work is expected to shed light on the quality of the switch surface contact as well as the optimum design of RF MEM switch surfaces.

  20. The fragrance hand immersion study - an experimental model simulating real-life exposure for allergic contact dermatitis on the hands

    DEFF Research Database (Denmark)

    Heydorn, S; Menné, T; Andersen, Klaus Ejner

    2003-01-01

    .p.m.), whilst during the following 2 weeks, the concentration was relatively high (approximately 250 p.p.m.), imitating real-life exposure to a household product like dishwashing liquid diluted in water and the undiluted product, respectively. Evaluation was made using a clinical scale and laser Doppler flow...... meter. 3 of 15 hand eczema patients developed eczema on the finger immersed in the fragrance-containing solution, 3 of 15 on the placebo finger and 3 of 15 on both fingers. Using this experimental exposure model simulating real-life exposure, we found no association between immersion of a finger...

  1. Torque characteristic analysis and measurement of axial flux-type non-contact permanent magnet device with Halbach array based on 3D analytical method

    Directory of Open Access Journals (Sweden)

    Gang-Hyeon Jang

    2017-05-01

    Full Text Available This paper addresses the torque characteristic analysis of an axial flux-type non-contact permanent magnet device with a Halbach magnet array using a 3D analytical method based on transfer relations. We obtain the magnetic field distribution due to the permanent magnet. The magnetic torque is derived from the magnetic field using a Maxwell stress tensor. The analytical results are validated extensively by comparison with 3D finite element analysis. Therefore, we derive an accurate analytical solution to reduce the analysis time, and we present an experimental verification using a manufactured model.

  2. Experimental studies of contact angle hysteresis phenomena on polymer surfaces – Toward the understanding and control of wettability for different applications.

    Science.gov (United States)

    Grundke, K; Pöschel, K; Synytska, A; Frenzel, R; Drechsler, A; Nitschke, M; Cordeiro, A L; Uhlmann, P; Welzel, P B

    2015-08-01

    Contact angle hysteresis phenomena on polymer surfaces have been studied by contact angle measurements using sessile liquid droplets and captive air bubbles in conjunction with a drop shape method known as Axisymmetric Drop Shape Analysis - Profile (ADSA-P). In addition, commercially available sessile drop goniometer techniques were used. The polymer surfaces were characterized with respect to their surface structure (morphology, roughness, swelling) and surface chemistry (elemental surface composition, acid-base characteristics) by scanning electron microscopy (SEM), scanning force microscopy (SFM), ellipsometry, X-ray photoelectron spectroscopy (XPS) and streaming potential measurements. Heterogeneous polymer surfaces with controlled roughness and chemical composition were prepared by different routes using plasma etching and subsequent dip coating or grafting of polymer brushes, anodic oxidation of aluminium substrates coated with thin polymer films, deposition techniques to create regular patterned and rough fractal surfaces from core-shell particles, and block copolymers. To reveal the effects of swelling and reorientation at the solid/liquid interface contact angle hysteresis phenomena on polyimide surfaces, cellulose membranes, and thermo-responsive hydrogels have been studied. The effect of different solutes in the liquid (electrolytes, surfactants) and their impact on contact angle hysteresis were characterized for solid polymers without and with ionizable functional surface groups in aqueous electrolyte solutions of different ion concentrations and pH and for photoresist surfaces in cationic aqueous surfactant solutions. The work is an attempt toward the understanding of contact angle hysteresis phenomena on polymer surfaces aimed at the control of wettability for different applications. Copyright © 2014 Elsevier B.V. All rights reserved.

  3. A finger-like hardness tester based on the contact electromechanical impedance of a piezoelectric bimorph cantilever.

    Science.gov (United States)

    Fu, Ji; Li, Faxin

    2015-10-01

    We proposed a finger-like hardness tester based on the electromechanical impedance of a piezoelectric bimorph cantilever. A Vickers indenter was fabricated to the free end of the bimorph to contact the sample. The contact force was monitored by a strain gauge and the contact area was obtained by tracking the bimorph's resonance frequency. The bimorph-sample contact system was modeled by the electromechanical equivalent circuit method. Verification experiments on standard hardness samples were conducted and the measured hardness values agreed well with those given by a conventional Vickers hardness tester. Further hardness measurement on a gear wheel showed that the proposed hardness tester is very adaptive and can be used for inner surface testing or in situ testing, where other hardness testers may not be applicable. The proposed hardness tester can be regarded as an improved ultrasonic hardness tester.

  4. Place-based social contact and mixing: a typology of generic meeting places of relevance for infectious disease transmission.

    Science.gov (United States)

    Strömgren, M; Holm, E; Dahlström, Ö; Ekberg, J; Eriksson, H; Spreco, A; Timpka, T

    2017-09-01

    This study aims to develop a typology of generic meeting places based on social contact and mixing of relevance for infectious disease transmission. Data were collected by means of a contact diary survey conducted on a representative sample of the Swedish population. The typology is derived from a cluster analysis accounting for four dimensions associated with transmission risk: visit propensity and its characteristics in terms of duration, number of other persons present and likelihood of physical contact. In the analysis, we also study demographic, socio-economic and geographical differences in the propensity of visiting meeting places. The typology identifies the family venue, the fixed activity site, the family vehicle, the trading plaza and the social network hub as generic meeting places. The meeting place typology represents a spatially explicit account of social contact and mixing relevant to infectious disease modelling, where the social context of the outbreak can be highlighted in light of the actual infectious disease.

  5. A neural circuit for robust time-to-contact estimation based on primate MST.

    Science.gov (United States)

    Browning, N Andrew

    2012-11-01

    Time-to-contact (TTC) estimation is beneficial for visual navigation. It can be estimated from an image projection, either in a camera or on the retina, by looking at the rate of expansion of an object. When expansion rate (E) is properly defined, TTC = 1/E. Primate dorsal MST cells have receptive field structures suited to the estimation of expansion and TTC. However, the role of MST cells in TTC estimation has been discounted because of large receptive fields, the fact that neither they nor preceding brain areas appear to decompose the motion field to estimate divergence, and a lack of experimental data. This letter demonstrates mathematically that template models of dorsal MST cells can be constructed such that the output of the template match provides an accurate and robust estimate of TTC. The template match extracts the relevant components of the motion field and scales them such that the output of each component of the template match is an estimate of expansion. It then combines these component estimates to provide a mean estimate of expansion across the object. The output of model MST provides a direct measure of TTC. The ViSTARS model of primate visual navigation was updated to incorporate the modified templates. In ViSTARS and in primates, speed is represented as a population code in V1 and MT. A population code for speed complicates TTC estimation from a template match. Results presented in this letter demonstrate that the updated template model of MST accurately codes TTC across a population of model MST cells. We conclude that the updated template model of dorsal MST simultaneously and accurately codes TTC and heading regardless of receptive field size, object size, or motion representation. It is possible that a subpopulation of MST cells in primates represents expansion in this way.

  6. Geometry based finite element modeling of the electrical contact between a cultured neuron and a microelectrode

    NARCIS (Netherlands)

    Buitenweg, Jan R.; Rutten, Wim; Marani, Enrico

    2003-01-01

    The electrical contact between a substrate embedded microelectrode and a cultured neuron depends on the geometry of the neuron-electrode interface. Interpretation and improvement of these contacts requires proper modeling of all coupling mechanisms. In literature, it is common practice to model the

  7. Investigation of contact acoustic nonlinearities on metal and composite airframe structures via intensity based health monitoring.

    Science.gov (United States)

    Romano, P Q; Conlon, S C; Smith, E C

    2013-01-01

    Nonlinear structural intensity (NSI) and nonlinear structural surface intensity (NSSI) based damage detection techniques were improved and extended to metal and composite airframe structures. In this study, the measurement of NSI maps at sub-harmonic frequencies was completed to provide enhanced understanding of the energy flow characteristics associated with the damage induced contact acoustic nonlinearity mechanism. Important results include NSI source localization visualization at ultra-subharmonic (nf/2) frequencies, and damage detection results utilizing structural surface intensity in the nonlinear domain. A detection metric relying on modulated wave spectroscopy was developed and implemented using the NSSI feature. The data fusion of the intensity formulation provided a distinct advantage, as both the single interrogation frequency NSSI and its modulated wave extension (NSSI-MW) exhibited considerably higher sensitivities to damage than using single-sensor (strain or acceleration) nonlinear detection metrics. The active intensity based techniques were also extended to composite materials, and results show both NSSI and NSSI-MW can be used to detect damage in the bond line of an integrally stiffened composite plate structure with high sensitivity. Initial damage detection measurements made on an OH-58 tailboom (Penn State Applied Research Laboratory, State College, PA) indicate the techniques can be transitioned to complex airframe structures achieving high detection sensitivities with minimal sensors and actuators.

  8. Synchrotron based x-ray fluorescence microscopy confirms copper in the corrosion products of metals in contact with treated wood

    Science.gov (United States)

    Samuel L. Zelinka; Joseph E. Jakes; Grant T. Kirker; David Vine; Stefan Vogt

    2017-01-01

    Copper based waterborne wood preservatives are frequently used to extend the service life of wood products when subjected to frequent moisture exposure. While these copper based treatments protect the wood from fungal decay and insect attack, they increase the corrosion of metals embedded or in contact with the treated wood. Previous research has shown the most...

  9. Experimental Bifurcation Analysis By Control-based Continuation - Determining Stability’

    DEFF Research Database (Denmark)

    Bureau, Emil; Santos, Ilmar; Thomsen, Jon Juel

    2012-01-01

    stable and unstable equilibrium states. We present the ongoing work of developing and applying the control-based continuation method to an experimental mechanical test-rig, consisting of a harmonically forced nonlinear impact oscillator controlled by electromagnetic actuators. Furthermore we propose...

  10. Experimental studies on an indigenous coconut shell based ...

    Indian Academy of Sciences (India)

    Satyabrata Sahoo

    Abstract. Experimental studies are carried out to characterize an indigenous, coconut shell based, activated carbon suitable for storage of natural gas. Properties such as BET surface area, micropore volume, average pore diameter and pore size distribution are obtained by using suitable instruments and techniques.

  11. Single-Subject Experimental Design for Evidence-Based Practice

    Science.gov (United States)

    Byiers, Breanne J.; Reichle, Joe; Symons, Frank J.

    2012-01-01

    Purpose: Single-subject experimental designs (SSEDs) represent an important tool in the development and implementation of evidence-based practice in communication sciences and disorders. The purpose of this article is to review the strategies and tactics of SSEDs and their application in speech-language pathology research. Method: The authors…

  12. Experimentally quantifying the advantages of weak-value-based metrology

    OpenAIRE

    Viza, Gerardo I.; Martínez-Rincón, Julián; Alves, Gabriel B.; Jordan, Andrew N.; Howell, John C.

    2014-01-01

    We experimentally investigate the relative advantages of implementing weak-value-based metrology versus standard methods. While the techniques outlined herein apply more generally, we measure small optical beam deflections both using a Sagnac interferometer with a monitored dark port (the weak-value-based technique), and by focusing the entire beam to a split detector (the standard technique). By introducing controlled external transverse detector modulations and transverse beam deflection mo...

  13. Experimental ultrasonic characterization of polyester-based materials for cultural heritage applications.

    Science.gov (United States)

    Arciniegas, Andres; Martinez, Loic; Briand, Arnaud; Prieto, Sophie; Serfaty, Stéphane; Wilkie-Chancellier, Nicolas

    2017-11-01

    For several years, the Réunion des musées nationaux - Grand-Palais has produced polyester resin reproductions in order to replace marble sculptures that have weakened by outdoor exposure. These objects are made of a complex multilayered polyester composite material including reinforcements to ensure the mechanical strength of the final structure and mineral fillers that allow to imitate the original aesthetics. However, the final structure also weakens because of constant outdoor exposure and ageing. This observation leads today to conduct research related to the structural health monitoring of reproductions for preventive conservation of cultural heritage. This paper presents a nondestructive technique to study the properties of the composite material used to produce reproductions of marble sculptures. Firstly, classical ultrasonic contact measurements were performed to estimate bulk properties and Rayleigh wave velocity. Secondly, experimental Rayleigh wave was measured using contact and laser vibrometry methods. The results show the potential of using ultrasonic surface wave propagation and laser vibrometry method to develop a minimum contact technique to study these polyester-based materials. The maximum relative uncertainty with respect to the expected theoretical Rayleigh wave velocity was close to 12%. Copyright © 2017 Elsevier B.V. All rights reserved.

  14. Toxicity testing and chemical analyses of recycled fibre-based paper for food contact

    DEFF Research Database (Denmark)

    Binderup, Mona-Lise; Pedersen, Gitte Alsing; Vinggaard, Anne

    2002-01-01

    of different qualities as food-contact materials and to Perform a preliminary evaluation of their suitability from a safety point of view, and, second, to evaluate the use of different in vitro toxicity tests for screening of paper and board. Paper produced from three different categories of recycled fibres (B......Food-contact materials, including paper, have to comply with a basic set of criteria concerning safety. This means that paper for food contact should not give rise to migration of components, which can endanger human health. The objectives of this pilot study were, first, to compare paper...

  15. [The study on non-contact detection of breathing and heartbeat based on radar principles].

    Science.gov (United States)

    Wang, J Q; Wang, H B; Jin, X J; Yang, G S; Yang, B; Dong, X Z; Qiu, L J

    2001-05-01

    The paper introduces the design of hardware and software of non-contact detection system for breathing and heartbeat in human body with radar principles and technology. The detection technology is discussed. Under conditions of the illuminating power P non-contact breathing and heartbeat measurement, can be in different positions and with different clothing on the subject. The results show that the system with the technology has a high sensitivity, and is harmless to the health. It is a practicable non-contact detection technology for breathing and heartbeat of human body.

  16. Development and study of novel non-contact ultrasonic motor based on principle of structural asymmetry.

    Science.gov (United States)

    Stepanenko, Dmitry A; Minchenya, Vladimir T

    2012-09-01

    The article presents novel design of non-contact rotary ultrasonic motor consisting of ring-shaped stator vibrating in in-plane flexural mode and rotor provided with blades. In contrast to other motors with similar design proposed motor relies on the use of standing ultrasonic waves. This simplifies design and electronic control of motor and becomes possible due to introduction of artificial asymmetry, for example by tilting one or several blades of the rotor relative to the surface normal. Operating principle of the proposed motor is based on acoustic radiation torque exerted on rotor by ultrasonic waves propagating in air or fluid gap between rotor and stator. This torque is calculated using finite element method by means of COMSOL Multiphysics software. Dynamics of rotor is studied using MathCad software and general theory of nonlinear conservative oscillators. Role of asymmetry is explained on the basis of comparative analysis of potential functions and phase trajectories for symmetric and asymmetric cases. It is shown that direction of rotation is determined by structural parameters of motor, particularly tilting direction (clockwise or counter-clockwise) of the blades. Conceptual design of motor with bidirectional rotation is described. Direction and velocity of rotation in the proposed conceptual design can be potentially controlled by changing excitation frequency of stator. Copyright © 2012 Elsevier B.V. All rights reserved.

  17. A non-contact high resolution piezoelectric film based sensor for monitoring breathing during sleep

    Science.gov (United States)

    Johnston, Robert; Nakano, Katsuya; Fujita, Kento; Misaki, Shinya; Fujii, Hiroyuki; Misaki, Yukinori

    2017-07-01

    Currently, research for measuring human breathing during sleep is actively being conducted into using technologies that include piezoelectric, ultrasonic, microwave and infrared rays. But various problems have led to not many practical applications. As such, it was decided to develop a PVDF (PolyVinylidene DiFluoride) based non-contact high resolution sensor for monitoring a subject's breathing as they sleep. Development of the high resolution respiration sensor was possible through the use of PVDF piezoelectric film and the development of a new sensor configuration. Although there was already an existing respiration sensor research resulting product available, is weak signal strength made it very sensitive to noise and difficult to measure respiration accurately. As such, complicated circuits and signal processing were needed. A new high resolution breathing sensor was developed with greater signal strength and with just the use of some simple circuits and signal processing, was able to accurately measure subject breathing. Also due to the greater signal strength, it became possible to measure both heart rate and respiration rate simultaneously.

  18. Disposable TSM-biosensor based on viscosity changes of the contacting medium.

    Science.gov (United States)

    Sakti, S P; Lucklum, R; Hauptmann, P; Bühling, F; Ansorge, S

    2001-12-01

    The thickness shear mode (TSM)-sensor responds to changes of mechanical properties of the material contacting the surface of the sensor. One of the material properties is the viscosity of a liquid. Abiosensor based on the TSM-resonator for the detection of endotoxin has been developed. It exploits the viscosity-density change during the reaction of endotoxin with limulus amebocyte lysate (LAL). The effect of surface properties of the sensor has been investigated to achieve better output signals. It is shown that the sensor requires a hydrophilic surface to get a better coupling between the sensor and the LAL-endotoxin solution. The TSM biosensor is able to detect an endotoxin concentration as low as 100 fg/ml by using only 50-microl standard LAL solution. The disadvantages of reusable sensors, such as the contamination from previous measurement of endotoxin and the cost of the regeneration or reclining processes of the sensor, have been eliminated by using a cost effective disposable TSM-sensor.

  19. New web-based algorithm to improve rigid gas permeable contact lens fitting in keratoconus.

    Science.gov (United States)

    Ortiz-Toquero, Sara; Rodriguez, Guadalupe; de Juan, Victoria; Martin, Raul

    2017-06-01

    To calculate and validate a new web-based algorithm for selecting the back optic zone radius (BOZR) of spherical gas permeable (GP) lens in keratoconus eyes. A retrospective calculation (n=35; multiple regression analysis) and a posterior prospective validation (new sample of 50 keratoconus eyes) of a new algorithm to select the BOZR of spherical KAKC design GP lenses (Conoptica) in keratoconus were conducted. BOZR calculated with the new algorithm, manufacturer guidelines and APEX software were compared with the BOZR that was finally prescribed. Number of diagnostic lenses, ordered lenses and visits to achieve optimal fitting were recorded and compared those obtained for a control group [50 healthy eyes fitted with spherical GP (BIAS design; Conoptica)]. The new algorithm highly correlated with the final BOZR fitted (r 2 =0.825, palgorithm demonstrated lower difference with the final BOZR prescribed (-0.01±0.12mm, p=0.65; 58% difference≤0.05mm) than with the manufacturer guidelines (+0.12±0.22mm, palgorithm (free access at www.calculens.com) improves spherical KAKC GP fitting in keratoconus and can reduce the practitioner and patient chair time to achieve a final acceptable fit in keratoconus. This algorithm reduces differences between keratoconus GP fitting (KAKC design) and standard GP (BIAS design) lenses fitting in healthy eyes. Copyright © 2016 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved.

  20. Corporate Consumer Contact API

    Data.gov (United States)

    General Services Administration — The data in the Corporate Consumer Contact API is based on the content you can find in the Corporate Consumer Contact listing in the Consumer Action Handbook (PDF)....

  1. Contact Angle Goniometer

    Data.gov (United States)

    Federal Laboratory Consortium — Description:The FTA32 goniometer provides video-based contact angle and surface tension measurement. Contact angles are measured by fitting a mathematical expression...

  2. Research advances in contact model and mechanism configuration for nut shelling manipulation based on metamorphic method

    Directory of Open Access Journals (Sweden)

    Xiulan BAO

    2017-04-01

    Full Text Available Nuts are the important economic forest tree species of China. De-shell is the key operation of nut deep processing. There are some problems in the current nut cracking devices such as the low decorticating rate, the high nuts losses rate and nutmeat integrity problems, etc.. The foundation of force analysis is to establish contact model for nut and mechanical. The nut surface is rough and irregular, so the contact area cannot be modeled as regular shape. How to set up contact constraint model is the key problem to accomplish non-loss shelling. In order to study the shell-breaking mechanism and structural design of the nut shelling manipulation, a multi-fingered metamorphic manipulator is presented. An overview of the nut shelling technology and the contact manipulator modeling are proposed. The origin and application of metamorphic mechanisms are introduced. Then the research contents and development prospects of nut shelling manipulator are described.

  3. Contact effects analyzed by a parameter extraction method based on a single bottom-gate/top-contact organic thin-film transistor

    Science.gov (United States)

    Takagaki, Shunsuke; Yamada, Hirofumi; Noda, Kei

    2018-03-01

    Contact effects in organic thin-film transistors (OTFTs) were examined by using our previously proposed parameter extraction method from the electrical characteristics of a single staggered-type device. Gate-voltage-dependent contact resistance and channel mobility in the linear regime were evaluated for bottom-gate/top-contact (BGTC) pentacene TFTs with active layers of different thicknesses, and for pentacene TFTs with contact-doped layers prepared by coevaporation of pentacene and tetrafluorotetracyanoquinodimethane (F4TCNQ). The extracted parameters suggested that the influence of the contact resistance becomes more prominent with the larger active-layer thickness, and that contact-doping experiments give rise to a drastic decrease in the contact resistance and a concurrent considerable improvement in the channel mobility. Additionally, the estimated energy distributions of trap density in the transistor channel probably reflect the trap filling with charge carriers injected into the channel regions. The analysis results in this study confirm the effectiveness of our proposed method, with which we can investigate contact effects and circumvent the influences of characteristic variations in OTFT fabrication.

  4. Tribological Behavior of Si3N4/Ti3SiC2 Contacts Lubricated by Lithium-Based Ionic Liquids

    Directory of Open Access Journals (Sweden)

    Haizhong Wang

    2014-01-01

    Full Text Available The tribological performance of Si3N4 ball sliding against Ti3SiC2 disc lubricated by lithium-based ionic liquids (ILs was investigated using an Optimol SRV-IV oscillating reciprocating friction and wear tester at room temperature (RT and elevated temperature (100°C. Glycerol and the conventional imidazolium-based IL 1-hexyl-3-methylimidazolium bis(trifluoromethylsulfonylimide (L-F106 were used as references under the same experimental conditions. The results show that the lithium-based ILs had higher thermal stabilities than glycerol and lower costs associated with IL preparation than L-F106. The tribotest results show that the lithium-based ILs were effective in reducing the friction and wear of Si3N4/Ti3SiC2 contacts. [Li(urea]TFSI even produced better tribological properties than glycerol and L-F106 both at RT and 100°C. The SEM/EDS and XPS results reveal that the excellent tribological endurance of Si3N4/Ti3SiC2 contacts lubricated by lithium-based ILs was mainly attributed to the formation of surface protective films composed of various tribochemical products.

  5. Template-based and free modeling of I-TASSER and QUARK pipelines using predicted contact maps in CASP12.

    Science.gov (United States)

    Zhang, Chengxin; Mortuza, S M; He, Baoji; Wang, Yanting; Zhang, Yang

    2018-03-01

    We develop two complementary pipelines, "Zhang-Server" and "QUARK", based on I-TASSER and QUARK pipelines for template-based modeling (TBM) and free modeling (FM), and test them in the CASP12 experiment. The combination of I-TASSER and QUARK successfully folds three medium-size FM targets that have more than 150 residues, even though the interplay between the two pipelines still awaits further optimization. Newly developed sequence-based contact prediction by NeBcon plays a critical role to enhance the quality of models, particularly for FM targets, by the new pipelines. The inclusion of NeBcon predicted contacts as restraints in the QUARK simulations results in an average TM-score of 0.41 for the best in top five predicted models, which is 37% higher than that by the QUARK simulations without contacts. In particular, there are seven targets that are converted from non-foldable to foldable (TM-score >0.5) due to the use of contact restraints in the simulations. Another additional feature in the current pipelines is the local structure quality prediction by ResQ, which provides a robust residue-level modeling error estimation. Despite the success, significant challenges still remain in ab initio modeling of multi-domain proteins and folding of β-proteins with complicated topologies bound by long-range strand-strand interactions. Improvements on domain boundary and long-range contact prediction, as well as optimal use of the predicted contacts and multiple threading alignments, are critical to address these issues seen in the CASP12 experiment. © 2017 Wiley Periodicals, Inc.

  6. Identification of Protein–Protein Interactions via a Novel Matrix-Based Sequence Representation Model with Amino Acid Contact Information

    Directory of Open Access Journals (Sweden)

    Yijie Ding

    2016-09-01

    Full Text Available Identification of protein–protein interactions (PPIs is a difficult and important problem in biology. Since experimental methods for predicting PPIs are both expensive and time-consuming, many computational methods have been developed to predict PPIs and interaction networks, which can be used to complement experimental approaches. However, these methods have limitations to overcome. They need a large number of homology proteins or literature to be applied in their method. In this paper, we propose a novel matrix-based protein sequence representation approach to predict PPIs, using an ensemble learning method for classification. We construct the matrix of Amino Acid Contact (AAC, based on the statistical analysis of residue-pairing frequencies in a database of 6323 protein–protein complexes. We first represent the protein sequence as a Substitution Matrix Representation (SMR matrix. Then, the feature vector is extracted by applying algorithms of Histogram of Oriented Gradient (HOG and Singular Value Decomposition (SVD on the SMR matrix. Finally, we feed the feature vector into a Random Forest (RF for judging interaction pairs and non-interaction pairs. Our method is applied to several PPI datasets to evaluate its performance. On the S . c e r e v i s i a e dataset, our method achieves 94 . 83 % accuracy and 92 . 40 % sensitivity. Compared with existing methods, and the accuracy of our method is increased by 0 . 11 percentage points. On the H . p y l o r i dataset, our method achieves 89 . 06 % accuracy and 88 . 15 % sensitivity, the accuracy of our method is increased by 0 . 76 % . On the H u m a n PPI dataset, our method achieves 97 . 60 % accuracy and 96 . 37 % sensitivity, and the accuracy of our method is increased by 1 . 30 % . In addition, we test our method on a very important PPI network, and it achieves 92 . 71 % accuracy. In the Wnt-related network, the accuracy of our method is increased by 16 . 67 % . The source code and all

  7. A Solid-Contact Indium(III) Sensor based on a Thiosulfinate Ionophore Derived from Omeprazole

    Energy Technology Data Exchange (ETDEWEB)

    Abbas, Mohammad Nooredeen; Hend Samy Amer [National Research Centre, Cairo (Egypt)

    2013-04-15

    A novel solid-contact indium(III)-selective sensor based on bis-(1H-benzimidazole-5-methoxy-2-[(4-methoxy-3, 5-dimethyl-1-pyridinyl) 2-methyl]) thiosulfinate, known as an omeprazole dimer (OD) and a neutral ionophore, was constructed, and its performance characteristics were evaluated. The sensor was prepared by applying a membrane cocktail containing the ionophore to a graphite rod pre-coated with polyethylene dioxythiophene (PEDOT) conducting polymer as the ion-to-electron transducer. The membrane contained 3.6% OD, 2.3% oleic acid (OA) and 62% dioctyl phthalate (DOP) as the solvent mediator in PVC and produced a good potentiometric response to indium(III) ions with a Nernstian slope of 19.09 mV/decade. The constructed sensor possessed a linear concentration range from 3 Χ 10{sup -7} to 1 Χ 10{sup -2} M and a lower detection limit (LDL) of 1 Χ 10{sup -7} M indium(III) over a pH range of 4.0-7.0. It also displayed a fast response time and good selectivity for indium(III) over several other ions. The sensor can be used for longer than three months without any considerable divergence in potential. The sensor was utilized for direct and flow injection potentiometric (FIP) determination of indium(III) in alloys. The parameters that control the flow injection method were optimized. Indium(III) was quantitatively recovered, and the results agreed with those obtained using atomic absorption spectrophotometry, as confirmed by the f and t values. The sensor was also utilized as an indicator electrode for the potentiometric titration of fluoride in the presence of chloride, bromide, iodide and thiocyanate ions using indium(III) nitrate as the titrant.

  8. Non-contact Real-time heart rate measurements based on high speed circuit technology research

    Science.gov (United States)

    Wu, Jizhe; Liu, Xiaohua; Kong, Lingqin; Shi, Cong; Liu, Ming; Hui, Mei; Dong, Liquan; Zhao, Yuejin

    2015-08-01

    In recent years, morbidity and mortality of the cardiovascular or cerebrovascular disease, which threaten human health greatly, increased year by year. Heart rate is an important index of these diseases. To address this status, the paper puts forward a kind of simple structure, easy operation, suitable for large populations of daily monitoring non-contact heart rate measurement. In the method we use imaging equipment video sensitive areas. The changes of light intensity reflected through the image grayscale average. The light change is caused by changes in blood volume. We video the people face which include the sensitive areas (ROI), and use high-speed processing circuit to save the video as AVI format into memory. After processing the whole video of a period of time, we draw curve of each color channel with frame number as horizontal axis. Then get heart rate from the curve. We use independent component analysis (ICA) to restrain noise of sports interference, realized the accurate extraction of heart rate signal under the motion state. We design an algorithm, based on high-speed processing circuit, for face recognition and tracking to automatically get face region. We do grayscale average processing to the recognized image, get RGB three grayscale curves, and extract a clearer pulse wave curves through independent component analysis, and then we get the heart rate under the motion state. At last, by means of compare our system with Fingertip Pulse Oximeter, result show the system can realize a more accurate measurement, the error is less than 3 pats per minute.

  9. Prediction of contact residue pairs based on co-substitution between sites in protein structures.

    Directory of Open Access Journals (Sweden)

    Sanzo Miyazawa

    Full Text Available Residue-residue interactions that fold a protein into a unique three-dimensional structure and make it play a specific function impose structural and functional constraints in varying degrees on each residue site. Selective constraints on residue sites are recorded in amino acid orders in homologous sequences and also in the evolutionary trace of amino acid substitutions. A challenge is to extract direct dependences between residue sites by removing phylogenetic correlations and indirect dependences through other residues within a protein or even through other molecules. Rapid growth of protein families with unknown folds requires an accurate de novo prediction method for protein structure. Recent attempts of disentangling direct from indirect dependences of amino acid types between residue positions in multiple sequence alignments have revealed that inferred residue-residue proximities can be sufficient information to predict a protein fold without the use of known three-dimensional structures. Here, we propose an alternative method of inferring coevolving site pairs from concurrent and compensatory substitutions between sites in each branch of a phylogenetic tree. Substitution probability and physico-chemical changes (volume, charge, hydrogen-bonding capability, and others accompanied by substitutions at each site in each branch of a phylogenetic tree are estimated with the likelihood of each substitution, and their direct correlations between sites are used to detect concurrent and compensatory substitutions. In order to extract direct dependences between sites, partial correlation coefficients of the characteristic changes along branches between sites, in which linear multiple dependences on feature vectors at other sites are removed, are calculated and used to rank coevolving site pairs. Accuracy of contact prediction based on the present coevolution score is comparable to that achieved by a maximum entropy model of protein sequences for 15

  10. Electrical contacts to individual SWCNTs: A review

    Directory of Open Access Journals (Sweden)

    Wei Liu

    2014-11-01

    Full Text Available Owing to their superior electrical characteristics, nanometer dimensions and definable lengths, single-walled carbon nanotubes (SWCNTs are considered as one of the most promising materials for various types of nanodevices. Additionally, they can be used as either passive or active elements. To be integrated into circuitry or devices, they are typically connected with metal leads to provide electrical contacts. The properties and quality of these electrical contacts are important for the function and performance of SWCNT-based devices. Since carbon nanotubes are quasi-one-dimensional structures, contacts to them are different from those for bulk semiconductors. Additionally, some techniques used in Si-based technology are not compatible with SWCNT-based device fabrication, such as the contact area cleaning technique. In this review, an overview of the investigations of metal–SWCNT contacts is presented, including the principle of charge carrier injection through the metal–SWCNT contacts and experimental achievements. The methods for characterizing the electrical contacts are discussed as well. The parameters which influence the contact properties are summarized, mainly focusing on the contact geometry, metal type and the cleanliness of the SWCNT surface affected by the fabrication processes. Moreover, the challenges for widespread application of CNFETs are additionally discussed.

  11. Laser-Based Lighting: Experimental Analysis and Perspectives

    Directory of Open Access Journals (Sweden)

    Nicola Trivellin

    2017-10-01

    Full Text Available This paper presents an extensive analysis of the operating principles, theoretical background, advantages and limitations of laser-based lighting systems. In the first part of the paper we discuss the main advantages and issues of laser-based lighting, and present a comparison with conventional LED-lighting technology. In the second part of the paper, we present original experimental data on the stability and reliability of phosphor layers for laser lighting, based on high light-intensity and high-temperature degradation tests. In the third part of the paper (for the first time we present a detailed comparison between three different solutions for laser lighting, based on (i transmissive phosphor layers; (ii a reflective/angled phosphor layer; and (iii a parabolic reflector, by discussing the advantages and drawbacks of each approach. The results presented within this paper can be used as a guideline for the development of advanced lighting systems based on laser diodes.

  12. Analysis of Seismic Damage of Underground Powerhouse Structure of Hydropower Plants Based on Dynamic Contact Force Method

    Directory of Open Access Journals (Sweden)

    Yang Yang

    2014-01-01

    Full Text Available Based on the characteristics of the dynamic interaction between an underground powerhouse concrete structure and its surrounding rock in a hydropower plant, an algorithm of dynamic contact force was proposed. This algorithm enables the simulation of three states of contact surface under dynamic loads, namely, cohesive contact, sliding contact, and separation. It is suitable for the numerical analysis of the dynamic response of the large and complex contact system consisting of underground powerhouse concrete structure and the surrounding rock. This algorithm and a 3D plastic-damage model were implemented in a dynamic computing platform, SUCED, to analyze the dynamic characteristics of the underground powerhouse structure of Yingxiuwan Hydropower Plant. By comparing the numerical results and postearthquake investigations, it was concluded that the amplitude and duration of seismic waves were the external factors causing seismic damage of the underground powerhouse structure, and the spatial variations in structural properties were the internal factors. The existence of rock mass surrounding the underground powerhouse was vital to the seismic stability of the structure. This work provides the theoretical basis for the anti-seismic design of underground powerhouse structures.

  13. Contact electrification in aerosolized monodispersed silica microspheres quantified using laser based velocimetry

    DEFF Research Database (Denmark)

    Alois, Stefano; Merrison, Jonathan P.; Iversen, Jens Jacob

    2017-01-01

    interacting with the injector tube have been seen to become electrified with a relatively narrow range of surface charge concentration of around Q/4πr2 ~ −100 e-/µm2 (~ −0.02mC/m2) for all particle sizes. Several combinations of aerosol particle and injector tube composition were also investigated, some...... experiments (effect are discussed, including the possibility of field emission at the contact site. In the future this technique is intended also to be applied to particle-particle induced contact electrification and its material dependence.......The contact electrification of aerosolized micro particles has been studied using a novel technique involving laser velocimetry. This has allowed the simultaneous determination of size and electrical charge of individual silica microspheres (in the range 1 – 8 µm). Interestingly the particles...

  14. COMSAT: Residue contact prediction of transmembrane proteins based on support vector machines and mixed integer linear programming.

    Science.gov (United States)

    Zhang, Huiling; Huang, Qingsheng; Bei, Zhendong; Wei, Yanjie; Floudas, Christodoulos A

    2016-03-01

    In this article, we present COMSAT, a hybrid framework for residue contact prediction of transmembrane (TM) proteins, integrating a support vector machine (SVM) method and a mixed integer linear programming (MILP) method. COMSAT consists of two modules: COMSAT_SVM which is trained mainly on position-specific scoring matrix features, and COMSAT_MILP which is an ab initio method based on optimization models. Contacts predicted by the SVM model are ranked by SVM confidence scores, and a threshold is trained to improve the reliability of the predicted contacts. For TM proteins with no contacts above the threshold, COMSAT_MILP is used. The proposed hybrid contact prediction scheme was tested on two independent TM protein sets based on the contact definition of 14 Å between Cα-Cα atoms. First, using a rigorous leave-one-protein-out cross validation on the training set of 90 TM proteins, an accuracy of 66.8%, a coverage of 12.3%, a specificity of 99.3% and a Matthews' correlation coefficient (MCC) of 0.184 were obtained for residue pairs that are at least six amino acids apart. Second, when tested on a test set of 87 TM proteins, the proposed method showed a prediction accuracy of 64.5%, a coverage of 5.3%, a specificity of 99.4% and a MCC of 0.106. COMSAT shows satisfactory results when compared with 12 other state-of-the-art predictors, and is more robust in terms of prediction accuracy as the length and complexity of TM protein increase. COMSAT is freely accessible at http://hpcc.siat.ac.cn/COMSAT/. © 2016 Wiley Periodicals, Inc.

  15. Unified Analysis of Multi-Chamber Contact Tanks and Mixing Efficiency Evaluation Based on Vorticity Field. Part II: Transport Analysis

    Directory of Open Access Journals (Sweden)

    Ender Demirel

    2016-11-01

    Full Text Available Mixing characteristics of multi-chambered contact tank are analyzed employing the validated three-dimensional numerical model developed in the companion paper. Based on the flow characterization, novel volumetric mixing efficiency definitions are proposed for the assessment of the hydrodynamic and chemical transport properties of the contact tank and its chambers. Residence time distribution functions are analyzed not only at the outlet of each chamber but also inside the chambers using the efficiency definitions for both Reynolds averaged Navier–Stokes (RANS and large eddy simulation (LES results. A novel tracer mixing index is defined to characterize short circuiting and mixing effects of the contact system. Comparisons of the results of these indexes for RANS and LES solutions indicate that mixing characteristics are stronger in LES due to the unsteady turbulent eddy mixing even though short circuiting effects are also more prominent in LES results. This result indicates that the mixing analysis based on the LES results simulates the mixing characteristics instantaneously, which is more realistic than that in RANS. Since LES analysis can capture turbulent eddy mixing better than RANS analysis, the interaction of recirculation and jet zones are captured more effectively in LES, which tends to predict higher turbulent mixing in the contact system. The analysis also shows that the mixing efficiency of each chamber of the contact tank is different, thus it is necessary to consider distinct chemical release and volumetric designs for each chamber in order to maximize the mixing efficiency of the overall process in a contact tank system.

  16. a-Si:H/c-Si heterojunction front- and back contacts for silicon solar cells with p-type base

    Energy Technology Data Exchange (ETDEWEB)

    Rostan, Philipp Johannes

    2010-07-01

    This thesis reports on low temperature amorphous silicon back and front contacts for high-efficiency crystalline silicon solar cells with a p-type base. The back contact uses a sequence of intrinsic amorphous (i-a-Si:H) and boron doped microcrystalline (p-{mu}c-Si:H) silicon layers fabricated by Plasma Enhanced Chemical Vapor Deposition (PECVD) and a magnetron sputtered ZnO:Al layer. The back contact is finished by evaporating Al onto the ZnO:Al and altogether prepared at a maximum temperature of 220 C. Analysis of the electronic transport of mobile charge carriers at the back contact shows that the two high-efficiency requirements low back contact series resistance and high quality c-Si surface passivation are in strong contradiction to each other, thus difficult to achieve at the same time. The preparation of resistance- and effective lifetime samples allows one to investigate both requirements independently. Analysis of the majority charge carrier transport on complete Al/ZnO:Al/a-Si:H/c-Si back contact structures derives the resistive properties. Measurements of the effective minority carrier lifetime on a-Si:H coated wafers determines the back contact surface passivation quality. Both high-efficiency solar cell requirements together are analyzed in complete photovoltaic devices where the back contact series resistance mainly affects the fill factor and the back contact passivation quality mainly affects the open circuit voltage. The best cell equipped with a diffused emitter with random texture and a full-area a-Si:H/c-Si back contact has an independently confirmed efficiency {eta} = 21.0 % with an open circuit voltage V{sub oc} = 681 mV and a fill factor FF = 78.7 % on an area of 1 cm{sup 2}. An alternative concept that uses a simplified a-Si:H layer sequence combined with Al-point contacts yields a confirmed efficiency {eta} = 19.3 % with an open circuit voltage V{sub oc} = 655 mV and a fill factor FF = 79.5 % on an area of 2 cm{sup 2}. Analysis of the

  17. Speckle-based off-axis holographic detection for non-contact photoacoustic tomography

    Directory of Open Access Journals (Sweden)

    Buj C.

    2015-09-01

    Full Text Available A very fast innovative holographic off-axis non-contact detection method for Photoacoustic Tomography (PAT is introduced. It overcomes the main problems of most state-of-the-art photoacoustic imaging approaches that are long acquisition times and the requirement of acoustic contact. In order to increase the acquisition speed significantly, the surface displacements of the object, caused by the photoacoustic pressure waves, are measured interferometrically in two dimensions. Phase alterations in the observed speckle field are used to identify changes in the object’s topography. A sampling rate of up to 80 MHz is feasible, which reduces the occurrence of motion artefacts.

  18. Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array.

    Science.gov (United States)

    Navruz, Isa; Coskun, Ahmet F; Wong, Justin; Mohammad, Saqib; Tseng, Derek; Nagi, Richie; Phillips, Stephen; Ozcan, Aydogan

    2013-10-21

    We demonstrate a cellphone based contact microscopy platform, termed Contact Scope, which can image highly dense or connected samples in transmission mode. Weighing approximately 76 grams, this portable and compact microscope is installed on the existing camera unit of a cellphone using an opto-mechanical add-on, where planar samples of interest are placed in contact with the top facet of a tapered fiber-optic array. This glass-based tapered fiber array has ~9 fold higher density of fiber optic cables on its top facet compared to the bottom one and is illuminated by an incoherent light source, e.g., a simple light-emitting-diode (LED). The transmitted light pattern through the object is then sampled by this array of fiber optic cables, delivering a transmission image of the sample onto the other side of the taper, with ~3× magnification in each direction. This magnified image of the object, located at the bottom facet of the fiber array, is then projected onto the CMOS image sensor of the cellphone using two lenses. While keeping the sample and the cellphone camera at a fixed position, the fiber-optic array is then manually rotated with discrete angular increments of e.g., 1-2 degrees. At each angular position of the fiber-optic array, contact images are captured using the cellphone camera, creating a sequence of transmission images for the same sample. These multi-frame images are digitally fused together based on a shift-and-add algorithm through a custom-developed Android application running on the smart-phone, providing the final microscopic image of the sample, visualized through the screen of the phone. This final computation step improves the resolution and also removes spatial artefacts that arise due to non-uniform sampling of the transmission intensity at the fiber optic array surface. We validated the performance of this cellphone based Contact Scope by imaging resolution test charts and blood smears.

  19. Screening Platform for Cell Contact Guidance Based on Inorganic Biomaterial Micro/nanotopographical Gradients.

    Science.gov (United States)

    Zhou, Qihui; Castañeda Ocampo, Olga; Guimarães, Carlos F; Kühn, Philipp T; van Kooten, Theo G; van Rijn, Patrick

    2017-09-20

    High-throughput screening (HTS) methods based on topography gradients or arrays have been extensively used to investigate cell-material interactions. However, it is a huge technological challenge to cost efficiently prepare topographical gradients of inorganic biomaterials due to their inherent material properties. Here, we developed a novel strategy translating PDMS-based wrinkled topography gradients with amplitudes from 49 to 2561 nm and wavelengths between 464 and 7121 nm to inorganic biomaterials (SiO2, Ti/TiO2, Cr/CrO3, and Al2O3) which are frequently used clinical materials. Optimal substratum conditions promoted human bone-marrow derived mesenchymal stem cell alignment, elongation, cytoskeleton arrangement, filopodia development as well as cell adhesion in vitro, which depended both on topography and interface material. This study displays a positive correlation between cell alignment and the orientation of cytoskeleton, filopodia, and focal adhesions. This platform vastly minimizes the experimental efforts both for inorganic material interface engineering and cell biological assessments in a facile and effective approach. The practical application of the HTS technology is expected to aid in the acceleration of developments of inorganic clinical biomaterials.

  20. Normal and friction stabilization techniques for interactive rigid body constraint-based contact force computations

    DEFF Research Database (Denmark)

    Silcowitz-Hansen, Morten; Abel, Sarah Maria Niebe; Erleben, Kenny

    2010-01-01

    We present a novel, yet simple, method for stabilization of normal forces. A normal stabilization term, carefully designed from hypotheses about interactive usability, is added to the contact force problem. Further, we propose friction stabilization as a completely new stabilization paradigm in i...

  1. Contact ion pair formation between hard acids and soft bases in aqueous solutions observed with 2DIR spectroscopy.

    Science.gov (United States)

    Sun, Zheng; Zhang, Wenkai; Ji, Minbiao; Hartsock, Robert; Gaffney, Kelly J

    2013-12-12

    The interaction of charged species in aqueous solution has important implications for chemical, biological, and environmental processes. We have used 2DIR spectroscopy to study the equilibrium dynamics of thiocyanate chemical exchange between free ion (NCS(-)) and contact ion pair configurations (MNCS(+)), where M(2+) = Mg(2+) or Ca(2+). Detailed studies of the influence of anion concentration and anion speciation show that the chemical exchange observed with the 2DIR measurements results from NCS(-) exchanging with other anion species in the first solvation shell surrounding Mg(2+) or Ca(2+). The presence of chemical exchange in the 2DIR spectra provides an indirect, but robust, determinant of contact ion pair formation. We observe preferential contact ion pair formation between soft Lewis base anions and hard Lewis acid cations. This observation cannot be easily reconciled with Pearson's acid-base concept or Collins' Law of Matching Water Affinities. The anions that form contact ion pairs also correspond to the ions with an affinity for water and protein surfaces, so similar physical and chemical properties may control these distinct phenomena.

  2. Amorphous Ni–Zr layer applied for microstructure improvement of Ni-based ohmic contacts to SiC

    Energy Technology Data Exchange (ETDEWEB)

    Wzorek, M., E-mail: mwzorek@ite.waw.pl; Czerwinski, A.; Borysiewicz, M.A.; Gołaszewska, K.; Myśliwiec, M.; Ratajczak, J.; Piotrowska, A.; Kątcki, J.

    2015-09-15

    Highlights: • Thin Ni–Si layers on SiC were studied after annealing. • Different types of microstructural defects occur depending on Ni:Si ratio. • Mechanisms leading to morphology degradation are discussed. • Presented method improves the microstructure of ohmic contacts to SiC. - Abstract: The new approach to fabrication process of nickel-based ohmic contacts to silicon carbide (SiC) is presented. During the first annealing step (300 °C), the amorphous Ni–Zr layer retards diffusion between two nickel silicide layers, thus handling the contradictory requirements for optimal Ni:Si ratio. Different stoichiometry obtained in each silicide layer allows to preserve smooth interface with SiC and simultaneously to avoid relatively easily meltable Si-rich Ni–Si phases during high temperature annealing (1000 °C) and therefore prevents morphology degradation. After annealing at 1000 °C only one final nickel silicide layer is present and Zr atoms are agglomerated at its surface. Morphology of the final silicide layer is substantially improved when compared to typical Ni-based contacts obtained by similar high-temperature annealings. The improved microstructure of the ohmic contact is a promising advantage in terms of SiC devices reliability.

  3. Antioxidative Categorization of Twenty Amino Acids Based on Experimental Evaluation

    Directory of Open Access Journals (Sweden)

    Naijin Xu

    2017-11-01

    Full Text Available In view of the great importance bestowed on amino acids as antioxidants in oxidation resistance, we attempted two common redox titration methods in this report, including micro-potassium permanganate titration and iodometric titration, to measure the antioxidative capacity of 20 amino acids, which are the construction units of proteins in living organisms. Based on the relative intensities of the antioxidative capacity, we further conducted a quantitative comparison and found out that the product of experimental values obtained from the two methods was proven to be a better indicator for evaluating the relative antioxidative capacity of amino acids. The experimental results were largely in accordance with structural analysis made on amino acids. On the whole, the 20 amino acids concerned could be divided into two categories according to their antioxidative capacity. Seven amino acids, including tryptophan, methionine, histidine, lysine, cysteine, arginine and tyrosine, were greater in total antioxidative capacity compared with the other 13 amino acids.

  4. Antioxidative Categorization of Twenty Amino Acids Based on Experimental Evaluation.

    Science.gov (United States)

    Xu, Naijin; Chen, Guanqun; Liu, Hui

    2017-11-27

    In view of the great importance bestowed on amino acids as antioxidants in oxidation resistance, we attempted two common redox titration methods in this report, including micro-potassium permanganate titration and iodometric titration, to measure the antioxidative capacity of 20 amino acids, which are the construction units of proteins in living organisms. Based on the relative intensities of the antioxidative capacity, we further conducted a quantitative comparison and found out that the product of experimental values obtained from the two methods was proven to be a better indicator for evaluating the relative antioxidative capacity of amino acids. The experimental results were largely in accordance with structural analysis made on amino acids. On the whole, the 20 amino acids concerned could be divided into two categories according to their antioxidative capacity. Seven amino acids, including tryptophan, methionine, histidine, lysine, cysteine, arginine and tyrosine, were greater in total antioxidative capacity compared with the other 13 amino acids.

  5. Performance improvement inpolymer-based thin film transistor using modified bottom-contact structures with etched SiO{sub 2} layers

    Energy Technology Data Exchange (ETDEWEB)

    Park, Jeong Woo [R and D Center, Samsung Corning Precision Materials Co., Ltd, Asan (Korea, Republic of); You, Young Jun; Shim, Jae Won [Dept. of Electronics and Electrical Engineering, Dongguk University-Seoul, Seoul (Korea, Republic of)

    2017-02-15

    Polymer-based thin film transistors (TFTs) with a modified bottom-contact structure and etched SiO{sub 2} layer were developed and investigated. An increase in the field-effect mobility in the developed TFTs compared to TFTs with a normal bottom-contact structure was ascertained. A bottom-contact structure and the photolithographic processing method were used to ensure that the developed TFTs were suitable for commercial applications. Increased mobility of the modified bottom-contact structure was attributed to direct contact of the Au electrode with the active polymer layer.

  6. A systems-based food safety evaluation: an experimental approach.

    Science.gov (United States)

    Higgins, Charles L; Hartfield, Barry S

    2004-11-01

    Food establishments are complex systems with inputs, subsystems, underlying forces that affect the system, outputs, and feedback. Building on past exploration of the hazard analysis critical control point concept and Ludwig von Bertalanffy General Systems Theory, the National Park Service (NPS) is attempting to translate these ideas into a realistic field assessment of food service establishments and to use information gathered by these methods in efforts to improve food safety. Over the course of the last two years, an experimental systems-based methodology has been drafted, developed, and tested by the NPS Public Health Program. This methodology is described in this paper.

  7. Beyond Contact Tracing: Community-Based Early Detection for Ebola Response

    CERN Document Server

    Cooney, Daniel; Bar-Yam, Yaneer

    2015-01-01

    The 2014 Ebola outbreak in west Africa raised many questions about the control of infectious disease in an increasingly connected global society. Limited availability of contact information has made contact tracing difficult or impractical in combating the outbreak. We consider the development of multi-scale public health strategies and simulate policies for community-level response aimed at early screening of communities rather than individuals, as well as travel restrictions to prevent community cross-contamination. Our analysis shows community screening to be effective even at a relatively low level of compliance. In our simulations, 40% of individuals conforming to this policy is enough to stop the outbreak. Simulations with a 50% compliance rate are consistent with the case counts in Liberia during the period of rapid decline after mid September, 2014. We also find the travel restriction policies to be effective at reducing the risks associated with compliance substantially below the 40% level, shortenin...

  8. An Investigation of a New Social Networks Contact Suggestion Based on Face Recognition Algorithm

    Directory of Open Access Journals (Sweden)

    Ivan Zelinka

    2016-01-01

    Full Text Available Automated comparison of faces in the photographs is a well established discipline. The main aim of this paper is to describe an approach whereby face recognition can be used in suggestion of a new contacts. The new contact suggestion is a common technique used across all main social networks. Our approach uses a freely available face comparison called "Betaface" together with our automated processig of the user´s Facebook profile. The research´s main point of interest is the comparison of friend´s facial images in a social network itself, how to process such a great amount of photos and what additional sources of data should be used. In this approach we used our automated processing algorithm Betaface in the social network Facebook and for the additional data, the Flickr social network was used. The results and their quality are discussed at the end.

  9. Parameters affecting the functionality of additives in lubricated contacts:effect of base oil polarity

    OpenAIRE

    Naveira Suarez, Aldara

    2010-01-01

    Traditionally rolling contact fatigue observed in bearing field applications was subsurface initiated. However, despite the improvement of steel properties, some factors such as downsizing in bearing design, extreme loading of the bearings as well as demanding application conditions (start up-stop cycles) have led to an increase on the cases of surface damage related to surface initiated fatigue, that comes basically from surface distress. Possible causes leading to surface initiated fatigue ...

  10. Nanoparticle-based, spray-coated silver top contacts for efficient polymer solar cells

    OpenAIRE

    Girotto, Claudio; Rand, Barry P; Steudel, Soeren; Genoe, Jan; Heremans, Paul

    2009-01-01

    We demonstrate a solution-processed top electrode for large area organic electronic devices. A Ag nanoparticle solution is spray-coated directly on top of an inverted bulk-heterojunction organic solar cell through a shadow mask. After sintering the Ag nanoparticle film at 150 degrees C, a temperature which is compatible with processes on flexible substrates, cells show performances comparable to those of reference devices with evaporated top-contacts. (c) 2009 Elsevier B.V. All rights reserved.

  11. Back contact formation for p-type based a-Si:H/c-Si heterojunction solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Tucci, Mario; Serenelli, Luca; De Iuliis, Simona; Izzi, Massimo [ENEA Research Center Casaccia, Via Anguillarese 301, 00123 Rome (Italy); De Cesare, Giampiero; Caputo, Domenico [Department of Electronic Engineering, University ' ' Sapienza' ' , Via Eudossiana 18, 00184 Rome (Italy)

    2011-03-15

    Even if p-type silicon is a more common PV material, heterojunction solar cells on p-type c-Si are less popular than on n-type. In turn, it has been difficult to achieve high efficiency with double-sided heterojunction with intrinsic thin layer structure on p-type c-Si. The double-sided silicon heterojunction solar cell is more appropriate for n-type crystalline silicon wafers than for p-type c-Si ones because of larger band offset at the valence band edge between the amorphous and crystalline semiconductors with respect to the conduction band edge. Indeed, it represents a large barrier for majority carrier holes flowing through to the back contact. In turn at the backside, the small conduction band offset provides a much less effective mirror for the minority carrier electrons. We have found an alternative way to obtain a quasi-ohmic contact promoting the formation of a CrSi film on top of p-a-Si:H layer. This reduces the problem of low p-a-Si:H doping value and the high activation energy, leading to a better carrier collection. In this work we present a detailed investigation of the p-c-Si/i-a-Si:H/p-a-Si:H contact, comparing the experimental transport measurements with numerical model of the stacked structure. We verify the effectiveness of p-c-Si/i-a-Si:H/p-a-Si:H as back side contact on the heterojunction solar cell performances. (copyright 2011 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim) (orig.)

  12. Simultaneous Detection of Displacement, Rotation Angle, and Contact Pressure Using Sandpaper Molded Elastomer Based Triple Electrode Sensor.

    Science.gov (United States)

    Choi, Eunsuk; Sul, Onejae; Lee, Seung-Beck

    2017-09-06

    In this article, we report on a flexible sensor based on a sandpaper molded elastomer that simultaneously detects planar displacement, rotation angle, and vertical contact pressure. When displacement, rotation, and contact pressure are applied, the contact area between the translating top elastomer electrode and the stationary three bottom electrodes change characteristically depending on the movement, making it possible to distinguish between them. The sandpaper molded undulating surface of the elastomer reduces friction at the contact allowing the sensor not to affect the movement during measurement. The sensor showed a 0.25 mm −1 displacement sensitivity with a ±33 μm accuracy, a 0.027 degree −1 of rotation sensitivity with ~0.95 degree accuracy, and a 4.96 kP −1 of pressure sensitivity. For possible application to joint movement detection, we demonstrated that our sensor effectively detected the up-and-down motion of a human forefinger and the bending and straightening motion of a human arm.

  13. No evidence of horizontal infection in horses kept in close contact with dogs experimentally infected with canine influenza A virus (H3N8

    Directory of Open Access Journals (Sweden)

    Yamanaka Takashi

    2012-04-01

    Full Text Available Abstract Background Since equine influenza A virus (H3N8 was transmitted to dogs in the United States in 2004, the causative virus, which is called canine influenza A virus (CIV, has become widespread in dogs. To date, it has remained unclear whether or not CIV-infected dogs could transmit CIV to horses. To address this, we tested whether or not close contact between horses and dogs experimentally infected with CIV would result in its interspecies transmission. Methods Three pairs of animals consisting of a dog inoculated with CIV (108.3 egg infectious dose50/dog and a healthy horse were kept together in individual stalls for 15 consecutive days. During the study, all the dogs and horses were clinically observed. Virus titres in nasal swab extracts and serological responses were also evaluated. In addition, all the animals were subjected to a gross pathological examination after euthanasia. Results All three dogs inoculated with CIV exhibited clinical signs including, pyrexia, cough, nasal discharge, virus shedding and seroconversion. Gross pathology revealed lung consolidations in all the dogs, and Streptococcus equi subsp. zooepidemicus was isolated from the lesions. Meanwhile, none of the paired horses showed any clinical signs, virus shedding or seroconversion. Moreover, gross pathology revealed no lesions in the respiratory tracts including the lungs of the horses. Conclusions These findings may indicate that a single dog infected with CIV is not sufficient to constitute a source of CIV infection in horses.

  14. Six open questions about the migration of engineered nano-objects from polymer-based food-contact materials: a review.

    Science.gov (United States)

    Jokar, Maryam; Pedersen, Gitte Alsing; Loeschner, Katrin

    2017-03-01

    The use of nanomaterials in food-contact applications has created enormous interest in recent years. The potential migration of engineered nano-objects (ENOs) from food-contact materials (FCMs) is one of the most important concerns regarding potential human exposure to ENOs and health risks. Current research focusing on FCMs has often reached inconsistency regarding migration of ENOs. The scope of this critical review is to give a concise overview of the most relevant aspects of the subject, and to identify and discuss the major open questions in relation to migration of ENOs from FCMs. This includes the very fundamental questions whether ENOs can migrate from FCMs at all and what the potential release mechanisms of ENOs could be. The inconsistency of findings from experimental studies is highlighted based on the example of silver nanoparticle migration from polymer-based FCMs. Challenges in the detection and characterisation of ENOs in migration studies and the suitability of the most frequently used analytical techniques are discussed. Further, this review questions the suitability of standard food simulants and migration test conditions for FCMs as well as of conventional mathematical migration models. Considerations regarding the risk for consumers associated with migrating ENOs from FCMs are discussed.

  15. Single-subject experimental design for evidence-based practice.

    Science.gov (United States)

    Byiers, Breanne J; Reichle, Joe; Symons, Frank J

    2012-11-01

    Single-subject experimental designs (SSEDs) represent an important tool in the development and implementation of evidence-based practice in communication sciences and disorders. The purpose of this article is to review the strategies and tactics of SSEDs and their application in speech-language pathology research. The authors discuss the requirements of each design, followed by advantages and disadvantages. The logic and methods for evaluating effects in SSED are reviewed as well as contemporary issues regarding data analysis with SSED data sets. Examples of challenges in executing SSEDs are included. Specific exemplars of how SSEDs have been used in speech-language pathology research are provided throughout. SSED studies provide a flexible alternative to traditional group designs in the development and identification of evidence-based practice in the field of communication sciences and disorders.

  16. Experimental demonstration of dielectric structure based two beam acceleration.

    Energy Technology Data Exchange (ETDEWEB)

    Gai, W.; Conde, M. E.; Konecny, R.; Power, J. G.; Schoessow, P.; Sun, X.; Zou, P.

    2000-11-28

    We report on the experimental results of the dielectric based two beam accelerator (step-up transformer). By using a single high charge beam, we have generated and extracted a high power RF pulse from a 7.8 GHz primary dielectric structure and then subsequently transferred to a second accelerating structure with higher dielectric constant and smaller transverse dimensions. We have measured the energy change of a second (witness) beam passing through the acceleration stage. The measured gradient is >4 times the deceleration gradient. The detailed experiment of set-up and results of the measurements are dimmed. Future plans for the development of a 100 MeV demonstration accelerator based on this technique is presented.

  17. A novel methodology based on contact angle hysteresis approach for surface changes monitoring in model PMMA-Corega Tabs system

    Science.gov (United States)

    Pogorzelski, Stanisław J.; Berezowski, Zdzisław; Rochowski, Paweł; Szurkowski, Janusz

    2012-02-01

    The aim of the paper is to propose a quantitative description of dental surface modifications, resulting from application of Corega and oral cavity liquids, with several surface parameters derived from liquid/solid contact angle measurements. In particular, to predict the long-term effectiveness of denture cleansers in prosthetics, it is necessary to determine surface wettability variations for model dental materials/probe liquid systems related to the contamination effect caused by substances found in the oral cavity. A novel simple low-cost methodology, based on liquid drop contact angle hysteresis CAH approach developed by Chibowski, was adopted to trace solid surface free energy changes in the model PMMA-Corega Tabs interfacial layer. Contact angle and its hysteresis were studied with a sessile drop-inclined plate method in contact with a cleanser (Corega Tabs) and model liquids found in the oral cavity. The apparent solid surface free energy, adsorptive film pressure, work of adhesion and spreading were derived from contact angle hysteresis data for both model solid surfaces (reference) and samples affected by different reactive liquids for a certain time. A time-dependent surface wettability changes of dentures were expressed quantitatively in terms of the corresponding variations of the surface energy parameters which turned out to be unequivocally related to the cleanser exposure time and polarity of the liquids applied to the dental material. The novel methodology appeared to be a useful tool for long term surface characterization of dental materials treated with surfactants-containing liquids capable of forming adhesive layers. The time of optimal use and effectiveness of cleansers are also reflected dynamically in the corresponding variations of the surface wettability parameters. Further studies on a large group of dental surface-probe liquid systems are required to specify the role played by other important factors (liquid polarity, pH and temperature).

  18. Simultaneously Load and Extended Release of Betamethasone and Ciprofloxacin from Vitamin E-Loaded Silicone-Based Soft Contact Lenses.

    Science.gov (United States)

    Rad, Maryam Shayani; Mohajeri, Seyed Ahmad

    2016-09-01

    The purpose of the present study was to evaluate the efficacy of commercial soft contact lenses, loaded with vitamin E, as ocular drug delivery systems for simultaneous loading and release of ciprofloxacin (Cipro) and betamethasone (BMZ) in artificial tears. In this study, we applied vitamin E as a barrier to increase BMZ-Cipro loading into three commercial silicone-based soft contact lenses and control their simultaneous release into the artificial lachrymal fluid. Two different concentrations of vitamin E solution (0.1 and 0.2 g/ml) were used, and various parameters including changes in lens diameter, water content, ultraviolet-visible light (UV-Vis) transmittance, drug-binding properties, and drug release profile were investigated. The obtained results indicated that vitamin E significantly reduced the swelling properties of contact lenses in aqueous media, while it enhanced the lens diameter in both dry and hydrated states. Vitamin E had no significant effects on visible transmittance, while it blocked UV radiation, which could be harmful for the eye surface. Our findings revealed that vitamin E improved the simultaneous loading amount of BMZ-Cipro into soft contact lenses. Additionally, BMZ and Cipro release rates significantly reduced after using vitamin E as a hydrophobic diffusion barrier. After soaking the lenses in 0.1 and 0.2 g/ml of vitamin E solution, BMZ release time increased by 28.8-81.6 and 182.4-201 folds, respectively. Moreover, Cipro release time increased by 12-18 and 1152-2313 folds, respectively. The results of the present study indicated the efficacy of vitamin E as a diffusion barrier in developing a controlled drug delivery system for the simultaneous loading of BMZ and Cipro and sustaining their release from soft contact lenses.

  19. Ranking multiple docking solutions based on the conservation of inter-residue contacts

    KAUST Repository

    Oliva, Romina M.

    2013-06-17

    Molecular docking is the method of choice for investigating the molecular basis of recognition in a large number of functional protein complexes. However, correctly scoring the obtained docking solutions (decoys) to rank native-like (NL) conformations in the top positions is still an open problem. Herein we present CONSRANK, a simple and effective tool to rank multiple docking solutions, which relies on the conservation of inter-residue contacts in the analyzed decoys ensemble. First it calculates a conservation rate for each inter-residue contact, then it ranks decoys according to their ability to match the more frequently observed contacts. We applied CONSRANK to 102 targets from three different benchmarks, RosettaDock, DOCKGROUND, and Critical Assessment of PRedicted Interactions (CAPRI). The method performs consistently well, both in terms of NL solutions ranked in the top positions and of values of the area under the receiver operating characteristic curve. Its ideal application is to solutions coming from different docking programs and procedures, as in the case of CAPRI targets. For all the analyzed CAPRI targets where a comparison is feasible, CONSRANK outperforms the CAPRI scorers. The fraction of NL solutions in the top ten positions in the RosettaDock, DOCKGROUND, and CAPRI benchmarks is enriched on average by a factor of 3.0, 1.9, and 9.9, respectively. Interestingly, CONSRANK is also able to specifically single out the high/medium quality (HMQ) solutions from the docking decoys ensemble: it ranks 46.2 and 70.8% of the total HMQ solutions available for the RosettaDock and CAPRI targets, respectively, within the top 20 positions. © 2013 Wiley Periodicals, Inc.

  20. Development of steel head joints with fiberglass sucker rod on the base of contact stresses investigation

    Energy Technology Data Exchange (ETDEWEB)

    Kopey, B.V.; Kopey, L.B. [Ivano-Frankivsk State Technical Oil and Gas University (Ukraine); Maksymuk, A.V.; Shcherbyna, N.M. [National Ukrainian Academy of Sciences (Ukraine)

    1998-12-31

    The methods of calculation of contact stresses during cylinder shell tube - steel bandage interaction are presented. Tymoshenko`s generalized theory of shells serves as a basis for investigating steel head to fiberglass sucker rod joint strength. This theory allows to consider mechanical performance of composite materials. The problem is reduced to solving Fredholm integral equation of second degree. The numeric analysis is performed. Several joints of composite body with steel head are proposed. The full-size sucker rod fatigue tests are performed to determine the fatigue limit under the bending and axial cyclic loads in the medium of oil well fluids. (orig.)

  1. Experimentally quantifying the advantages of weak-value-based metrology

    Science.gov (United States)

    Viza, Gerardo I.; Martínez-Rincón, Julián; Alves, Gabriel B.; Jordan, Andrew N.; Howell, John C.

    2015-09-01

    We experimentally investigate the relative advantages of implementing weak-value-based metrology versus standard methods. While the techniques outlined herein apply more generally, we measure small optical beam deflections both using a Sagnac interferometer with a monitored dark port (the weak-value-based technique), and by focusing the entire beam to a split detector (the standard technique). By introducing controlled external transverse detector modulations and transverse beam deflection momentum modulations, we quantify the mitigation of these sources in the weak-value-based experiment versus the standard focusing experiment. The experiments are compared using a combination of deterministic and stochastic methods. In all cases, the weak-value technique performs the same or better than the standard technique by up to two orders of magnitude in precision for our parameters. We further measure the statistical efficiency of the weak-value-based technique. By postselecting on 1 % of the photons, we obtain 99 % of the available Fisher information of the beam deflection parameter.

  2. Investigating interfacial contact configuration and behavior of single-walled carbon nanotube-based nanodevice with atomistic simulations

    Energy Technology Data Exchange (ETDEWEB)

    Cui, Jianlei, E-mail: cjlxjtu@mail.xjtu.edu.cn; Zhang, Jianwei [Xi’an Jiaotong University, State Key Laboratory for Manufacturing Systems Engineering (China); He, Xiaoqiao, E-mail: bcxqhe@cityu.edu.hk [City University of Hong Kong, Department of Architecture and Civil Engineering (Hong Kong); Mei, Xuesong; Wang, Wenjun [Xi’an Jiaotong University, State Key Laboratory for Manufacturing Systems Engineering (China); Yang, Xinju [Fudan University, State Key Laboratory of Surface Physics and Department of Physics (China); Xie, Hui; Yang, Lijun; Wang, Yang [Harbin Institute of Technology, State Key Laboratory of Robotics and Systems (China)

    2017-03-15

    Carbon nanotubes (CNTs), including single-walled carbon nanotubes (SWNTs) and multi-walled carbon nanotubes (MWNTs), are considered to be the promising candidates for next-generation interconnects with excellent physical and chemical properties ranging from ultrahigh mechanical strength, to electrical properties, to thermal conductivity, to optical properties, etc. To further study the interfacial contact configurations of SWNT-based nanodevice with a 13.56-Å diameter, the corresponding simulations are carried out with the molecular dynamic method. The nanotube collapses dramatically into the surface with the complete collapse on the Au/Ag/graphite electrode surface and slight distortion on the Si/SiO{sub 2} substrate surface, respectively. The related dominant mechanism is studied and explained. Meanwhile, the interfacial contact configuration and behavior, depended on other factors, are also analyzed in this article.

  3. A contact-imaging based microfluidic cytometer with machine-learning for single-frame super-resolution processing.

    Directory of Open Access Journals (Sweden)

    Xiwei Huang

    Full Text Available Lensless microfluidic imaging with super-resolution processing has become a promising solution to miniaturize the conventional flow cytometer for point-of-care applications. The previous multi-frame super-resolution processing system can improve resolution but has limited cell flow rate and hence low throughput when capturing multiple subpixel-shifted cell images. This paper introduces a single-frame super-resolution processing with on-line machine-learning for contact images of cells. A corresponding contact-imaging based microfluidic cytometer prototype is demonstrated for cell recognition and counting. Compared with commercial flow cytometer, less than 8% error is observed for absolute number of microbeads; and 0.10 coefficient of variation is observed for cell-ratio of mixed RBC and HepG2 cells in solution.

  4. A portable, contact animal fundus imaging system based on Rol's GRIN lenses.

    Science.gov (United States)

    Hernandez, Victor; Albini, Thomas; Lee, William; Rowaan, Cornelis; Nankivil, Derek; Arrieta, Esdras; Parel, Jean-Marie

    2012-05-01

    To demonstrate a cost-effective, portable, and simple-to-use fundus imaging system for laboratory animals. Albino rats, pigmented mice, albino guinea pigs, and New Zealand white rabbits. A contact fundus imaging system was designed and constructed using standard optical and mechanical components: a digital camera, an otoscope, a fiber optic light source, and standard optical lenses and mounts. Digital fundus video and photography of two albino rats, two pigmented mice, two New Zealand white rabbits, and two albino guinea pigs were obtained. For all animals examined, pupils were dilated and local anesthetic was administered. Digital images of the fundus were obtained in all animals. Contrast of retinal vasculature and overall image quality varied from one species to another, as the axial length, ocular optics, and retinal reflectance varied significantly across species. Light intensity and focus were optimized via the light source and lens focusing mount to produce high-quality images for each animal. The portable, cost-effective contact fundus imaging system was easy to use for fundus examination of laboratory animals. © 2011 American College of Veterinary Ophthalmologists.

  5. Experimental investigation of the tip based micro/nano machining

    Science.gov (United States)

    Guo, Z.; Tian, Y.; Liu, X.; Wang, F.; Zhou, C.; Zhang, D.

    2017-12-01

    Based on the self-developed three dimensional micro/nano machining system, the effects of machining parameters and sample material on micro/nano machining are investigated. The micro/nano machining system is mainly composed of the probe system and micro/nano positioning stage. The former is applied to control the normal load and the latter is utilized to realize high precision motion in the xy plane. A sample examination method is firstly introduced to estimate whether the sample is placed horizontally. The machining parameters include scratching direction, speed, cycles, normal load and feed. According to the experimental results, the scratching depth is significantly affected by the normal load in all four defined scratching directions but is rarely influenced by the scratching speed. The increase of scratching cycle number can increase the scratching depth as well as smooth the groove wall. In addition, the scratching tests of silicon and copper attest that the harder material is easier to be removed. In the scratching with different feed amount, the machining results indicate that the machined depth increases as the feed reduces. Further, a cubic polynomial is used to fit the experimental results to predict the scratching depth. With the selected machining parameters of scratching direction d3/d4, scratching speed 5 μm/s and feed 0.06 μm, some more micro structures including stair, sinusoidal groove, Chinese character '田', 'TJU' and Chinese panda have been fabricated on the silicon substrate.

  6. Simulation-based optimal Bayesian experimental design for nonlinear systems

    KAUST Repository

    Huan, Xun

    2013-01-01

    The optimal selection of experimental conditions is essential to maximizing the value of data for inference and prediction, particularly in situations where experiments are time-consuming and expensive to conduct. We propose a general mathematical framework and an algorithmic approach for optimal experimental design with nonlinear simulation-based models; in particular, we focus on finding sets of experiments that provide the most information about targeted sets of parameters.Our framework employs a Bayesian statistical setting, which provides a foundation for inference from noisy, indirect, and incomplete data, and a natural mechanism for incorporating heterogeneous sources of information. An objective function is constructed from information theoretic measures, reflecting expected information gain from proposed combinations of experiments. Polynomial chaos approximations and a two-stage Monte Carlo sampling method are used to evaluate the expected information gain. Stochastic approximation algorithms are then used to make optimization feasible in computationally intensive and high-dimensional settings. These algorithms are demonstrated on model problems and on nonlinear parameter inference problems arising in detailed combustion kinetics. © 2012 Elsevier Inc.

  7. Smart-phone based computational microscopy using multi-frame contact imaging on a fiber-optic array

    Science.gov (United States)

    Navruz, Isa; Coskun, Ahmet F.; Wong, Justin; Mohammad, Saqib; Tseng, Derek; Nagi, Richie; Phillips, Stephen; Ozcan, Aydogan

    2013-01-01

    We demonstrate a cellphone based contact microscopy platform, termed Contact Scope, which can image highly dense or connected samples in transmission mode. Weighing approximately 76 grams, this portable and compact microscope is installed on the existing camera unit of a cellphone using an opto-mechanical add-on, where planar samples of interest are placed in contact with the top facet of a tapered fiber-optic array. This glass-based tapered fiber array has ∼9 fold higher density of fiber optic cables on its top facet compared to the bottom one and is illuminated by an incoherent light source, e.g., a simple light-emitting-diode (LED). The transmitted light pattern through the object is then sampled by this array of fiber optic cables, delivering a transmission image of the sample onto the other side of the taper, with ∼3× magnification in each direction. This magnified image of the object, located at the bottom facet of the fiber array, is then projected onto the CMOS image sensor of the cellphone using two lenses. While keeping the sample and the cellphone camera at a fixed position, the fiber-optic array is then manually rotated with discrete angular increments of e.g., 1-2 degrees. At each angular position of the fiber-optic array, contact images are captured using the cellphone camera, creating a sequence of transmission images for the same sample. These multi-frame images are digitally fused together based on a shift-and-add algorithm through a custom-developed Android application running on the smart-phone, providing the final microscopic image of the sample, visualized through the screen of the phone. This final computation step improves the resolution and also gets rid of spatial artefacts that arise due to non-uniform sampling of the transmission intensity at the fiber optic array surface. We validated the performance of this cellphone based Contact Scope by imaging resolution test charts and blood smears. PMID:23939637

  8. The importance of contact quality

    DEFF Research Database (Denmark)

    van Bakel, Marian; Gerritsen, Marinel; van Oudenhoven, Jan Pieter

    . Expatriates in the Netherlands were randomly divided into an experimental group (n = 33) of which 21 developed high-quality contact with their host, and a control group (n = 32) without host. The results show that contact quality plays an important role and suggest that the higher the quality of the contact...

  9. Experimental investigation of quench and re-wetting temperatures of hot horizontal tubes well above the limiting temperature for solid–liquid contact

    Energy Technology Data Exchange (ETDEWEB)

    Takrouri, Kifah, E-mail: takroukj@mcmaster.ca [Department of Engineering Physics, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L7 (Canada); Luxat, John, E-mail: luxatj@mcmaster.ca [Department of Engineering Physics, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L7 (Canada); Hamed, Mohamed [Thermal Processing Laboratory (TPL), Department of Mechanical Engineering, McMaster University, 1280 Main Street West, Hamilton, Ontario L8S 4L7 (Canada)

    2017-01-15

    Highlights: • Quench and re-wetting temperatures were measured upon jet quenching of hot cylindrical tubes. • Correlations have been developed and provided good fit of data. • Quench and re-wetting temperatures were found to greatly depend on water subcooling. • Stagnation point showed higher quench and re-wetting temperatures than other locations. • Quench temperature decreased by increasing surface curvature and tube conductivity. • Re-wetting temperature is a weak function of both variables. - Abstract: Quench cooling of a hot dry surface involves the rapid decrease in surface temperature resulting from bringing the hot surface into sudden contact with a coolant at a lower temperature. Quench temperature is the onset of the rapid decrease in surface temperature and corresponds to the onset of destabilization of a vapor film that exists between the hot surface and the coolant. Situations involving quench cooling are encountered in a number of postulated accidents in Canada Deuterium Uranium CANDU reactors, such as the quench of a hot calandria tube in certain Loss of Coolant Accidents LOCA. If the calandria tube temperature is not reduced by initiation of quench heat transfer, then this may lead to subsequent fuel channel failure and for this accident knowledge of quench heat transfer characteristics is of great importance. In this study, a Water Quench Facility WQF has been designed and built at the Thermal Processing Laboratory TPL at McMaster University and a series of experimental tests were carried out to investigate the quench of hot horizontal tubes using a vertical rectangular water multi-jet system. The tubes were heated to a temperature between 380 and 780 °C then cooled to the jet temperature. The temperature variation with time in tube circumferential and axial directions was measured. The two-phase flow behavior and the propagation of the re-wetting front around and along the tubes were simultaneously observed using a high-speed camera

  10. Experimental Results of Rover-Based Coring and Caching

    Science.gov (United States)

    Backes, Paul G.; Younse, Paulo; DiCicco, Matthew; Hudson, Nicolas; Collins, Curtis; Allwood, Abigail; Paolini, Robert; Male, Cason; Ma, Jeremy; Steele, Andrew; hide

    2011-01-01

    Experimental results are presented for experiments performed using a prototype rover-based sample coring and caching system. The system consists of a rotary percussive coring tool on a five degree-of-freedom manipulator arm mounted on a FIDO-class rover and a sample caching subsystem mounted on the rover. Coring and caching experiments were performed in a laboratory setting and in a field test at Mono Lake, California. Rock abrasion experiments using an abrading bit on the coring tool were also performed. The experiments indicate that the sample acquisition and caching architecture is viable for use in a 2018 timeframe Mars caching mission and that rock abrasion using an abrading bit may be feasible in place of a dedicated rock abrasion tool.

  11. Bases epistemológicas da psicologia cognitiva experimental

    Directory of Open Access Journals (Sweden)

    Carmem Beatriz Neufeld

    Full Text Available O presente artigo tem como objetivo analisar as bases epistemológicas da Psicologia Cognitiva Experimental. Inicialmente serão traçados alguns dos pressupostos da Psicologia Cognitiva, dentro da abrangência da Ciência Cognitiva e sua relação com o Cognitivismo. Serão retomados alguns aspectos históricos que serão relacionados com os pressupostos das teorias e suas influências na aplicação das mesmas. A partir destes aspectos, serão levantados alguns dos pressupostos filosóficos que marcaram a transição de modelos em ciência, enfocando por fim a emergência da Ciência Cognitiva. O presente trabalho conclui enfocando os argumentos pró e contra a revolução cognitiva enquanto quebra de paradigma com o Behaviorismo.

  12. Feedback control in deep drawing based on experimental datasets

    Science.gov (United States)

    Fischer, P.; Heingärtner, J.; Aichholzer, W.; Hortig, D.; Hora, P.

    2017-09-01

    In large-scale production of deep drawing parts, like in automotive industry, the effects of scattering material properties as well as warming of the tools have a significant impact on the drawing result. In the scope of the work, an approach is presented to minimize the influence of these effects on part quality by optically measuring the draw-in of each part and adjusting the settings of the press to keep the strain distribution, which is represented by the draw-in, inside a certain limit. For the design of the control algorithm, a design of experiments for in-line tests is used to quantify the influence of the blank holder force as well as the force distribution on the draw-in. The results of this experimental dataset are used to model the process behavior. Based on this model, a feedback control loop is designed. Finally, the performance of the control algorithm is validated in the production line.

  13. Experimental bit commitment based on quantum communication and special relativity.

    Science.gov (United States)

    Lunghi, T; Kaniewski, J; Bussières, F; Houlmann, R; Tomamichel, M; Kent, A; Gisin, N; Wehner, S; Zbinden, H

    2013-11-01

    Bit commitment is a fundamental cryptographic primitive in which Bob wishes to commit a secret bit to Alice. Perfectly secure bit commitment between two mistrustful parties is impossible through asynchronous exchange of quantum information. Perfect security is however possible when Alice and Bob split into several agents exchanging classical and quantum information at times and locations suitably chosen to satisfy specific relativistic constraints. Here we report on an implementation of a bit commitment protocol using quantum communication and special relativity. Our protocol is based on [A. Kent, Phys. Rev. Lett. 109, 130501 (2012)] and has the advantage that it is practically feasible with arbitrary large separations between the agents in order to maximize the commitment time. By positioning agents in Geneva and Singapore, we obtain a commitment time of 15 ms. A security analysis considering experimental imperfections and finite statistics is presented.

  14. Multiscale experimental mechanics of hierarchical carbon-based materials.

    Science.gov (United States)

    Espinosa, Horacio D; Filleter, Tobin; Naraghi, Mohammad

    2012-06-05

    Investigation of the mechanics of natural materials, such as spider silk, abalone shells, and bone, has provided great insight into the design of materials that can simultaneously achieve high specific strength and toughness. Research has shown that their emergent mechanical properties are owed in part to their specific self-organization in hierarchical molecular structures, from nanoscale to macroscale, as well as their mixing and bonding. To apply these findings to manmade materials, researchers have devoted significant efforts in developing a fundamental understanding of multiscale mechanics of materials and its application to the design of novel materials with superior mechanical performance. These efforts included the utilization of some of the most promising carbon-based nanomaterials, such as carbon nanotubes, carbon nanofibers, and graphene, together with a variety of matrix materials. At the core of these efforts lies the need to characterize material mechanical behavior across multiple length scales starting from nanoscale characterization of constituents and their interactions to emerging micro- and macroscale properties. In this report, progress made in experimental tools and methods currently used for material characterization across multiple length scales is reviewed, as well as a discussion of how they have impacted our current understanding of the mechanics of hierarchical carbon-based materials. In addition, insight is provided into strategies for bridging experiments across length scales, which are essential in establishing a multiscale characterization approach. While the focus of this progress report is in experimental methods, their concerted use with theoretical-computational approaches towards the establishment of a robust material by design methodology is also discussed, which can pave the way for the development of novel materials possessing unprecedented mechanical properties. Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  15. Time-Varying Total Stiffness Matrix of a Rigid Machine Spindle-Angular Contact Ball Bearings Assembly: Theory and Analytical/Experimental Verifications

    Directory of Open Access Journals (Sweden)

    Fawzi M.A. El-Saeidy

    2011-01-01

    Full Text Available A lagrangian formulation is presented for the total dynamic stiffness and damping matrices of a rigid rotor carrying noncentral rigid disk and supported on angular contact ball bearings (ACBBs. The bearing dynamic stiffness/damping marix is derived in terms of the bearing motions (displacements/rotations and then the principal of virtual work is used to transfer it from the bearing location to the rotor mass center to obtain the total dynamic stiffness/damping matrix. The bearing analyses take into account the bearing nonlinearities, cage rotation and bearing axial preload. The coefficients of these time-dependent matrices are presented analytically. The equations of motion of a rigid rotor-ACBBs assembly are derived using Lagrange's equation. The proposed analyses on deriving the bearing stiffness matrix are verified against existing bearing analyses of SKF researchers that, in turn, were verified using both SKF softwares/experiments and we obtained typical agreements. The presented total stiffness matrix is applied to a typical grinding machine spindle studied experimentally by other researchers and excellent agreements are obtained between our analytical eigenvalues and the experimental ones. The effect of using the total full stiffness matrix versus using the total diagonal stiffness matrix on the natural frequencies and dynamic response of the rigid rotor-bearings system is studied. It is found that using the diagonal matrix affects natural frequencies values (except the axial frequency and response amplitudes and pattern and causes important vibration tones to be missig from the response spectrum. Therefore it is recommended to use the full total stiffness matrix and not the diagonal matrix in the design/vibration analysis of these rotating machines. For a machine spindle-ACBBs assembly under mass unbalnce and a horizontal force at the spindle cutting nose when the bearing time-varying stiffness matrix (bearing cage rotation is considered

  16. Formaldehyde-releasers in cosmetics: relationship to formaldehyde contact allergy. Part 2. Patch test relationship to formaldehyde contact allergy, experimental provocation tests, amount of formaldehyde released, and assessment of risk to consumers allergic to formaldehyde.

    Science.gov (United States)

    de Groot, Anton; White, Ian R; Flyvholm, Mari-Ann; Lensen, Gerda; Coenraads, Pieter-Jan

    2010-01-01

    This is the second part of an article on formaldehyde-releasers in cosmetics. The patch test relationship between the releasers in cosmetics to formaldehyde contact allergy is reviewed and it is assessed whether products preserved with formaldehyde-releasers may contain enough free formaldehyde to pose a threat to individuals with contact allergy to formaldehyde. There is a clear relationship between positive patch test reactions to formaldehyde-releasers and formaldehyde contact allergy: 15% of all reactions to 2-bromo-2-nitropropane-1,3-diol and 40-60% of the reactions to the other releasers are caused by a reaction to the formaldehyde in the test material. There is only fragmented data on the amount of free formaldehyde in cosmetics preserved with formaldehyde donors. However, all releasers (with the exception of 2-bromo-2-nitropropane-1,3-diol, for which adequate data are lacking) can, in the right circumstances of concentration and product composition, release >200 p.p.m. formaldehyde, which may result in allergic contact dermatitis. Whether this is actually the case in any particular product cannot be determined from the ingredient labelling. Therefore, we recommend advising patients allergic to formaldehyde to avoid leave-on cosmetics preserved with quaternium-15, diazolidinyl urea, DMDM hydantoin, or imidazolidinyl urea, acknowledging that many would tolerate some products.

  17. Performances of some reduced bases for the stability analysis of a disc/pads system in sliding contact

    Science.gov (United States)

    Brizard, D.; Chiello, O.; Sinou, J.-J.; Lorang, X.

    2011-02-01

    The complex eigenvalue analysis is a widely used technique to investigate the stability of a dynamical system with frictional contact. In the case of brake systems, it is the most frequently employed method to study the propensity of the brake to generate squeal noise. When finite element models are considered, iterative solvers are needed to calculate the complex modes and eigenvalues with good precision. In practice, reduced real bases are often used in order to reduce the computational times. However, great attention should be focused on the errors introduced by the reduction, which is rarely done. In this paper, the performances of some reduced bases are investigated in the case of a simple disc/pads system. Bases composed of real coupled modes and bases provided by Component Mode Synthesis (CMS) techniques are tested. An enrichment of these bases is proposed in order to improve the precision of the results. In particular, new rubbing attachment modes are proposed to adapt free-interface CMS techniques to frictional contact. When real coupled modes are used, it is suggested to complete the basis by the static response to a first-order approximation of the friction forces. Applied to the disc/pads model, the different enrichment options allow a reduction of the errors on frequencies, divergence rates and mode shapes by a factor comprised between 10 and 100 without significantly increasing the computational times.

  18. Recruiting former melanoma patients via hospitals in comparison to office-based dermatologists in a register-based cohort study that required indirect contact

    Directory of Open Access Journals (Sweden)

    S. R. Zeissig

    2017-11-01

    Full Text Available Abstract Background There are detailed reviews about different recruitment strategies, but not with regard to differences between recruitment of hospital-based versus office-based physicians. Within this study, the two different recruitment schemes are compared. Advantages and disadvantages of different ways of recruitment in registry-based studies are discussed. Methods In a cross-sectional cancer-registry-based study, long-term melanoma patients were contacted by dermatologists rather than directly by the registry on the basis of the legal situation. Logistic regression models and generalized estimating equations were used to assess effects of various patient and physician characteristics on participation and data quality. Especially differences between hospital-based versus office-based dermatologists are evaluated. Results Seventy two out of 112 contacted dermatologists took part in the study (64.3%. The cooperation proportion was 52.2% (689 participants/1320 contacted patients. Participants and non-participants differed regarding age and sex, but not regarding other social demographic factors and cancer stage. We did not observe a difference in patient participation between hospital-based versus office-based dermatologists (OR 1.08 [CI 0.84–1.39]; p = 0.57. However, medical data provided by the cancer registry were better for participants registered and recruited by hospitals. Conclusions In cohort studies with epidemiological cancer registries, recruitment via physicians has potential disadvantages and is more complex. If this indirect way of contact is mandatory, we recommend recruitment procedures including hospital-based rather than office-based physicians. However, physician characteristics were not associated with outcome.

  19. Web Based Learning Support for Experimental Design in Molecular Biology.

    Science.gov (United States)

    Wilmsen, Tinri; Bisseling, Ton; Hartog, Rob

    An important learning goal of a molecular biology curriculum is a certain proficiency level in experimental design. Currently students are confronted with experimental approaches in textbooks, in lectures and in the laboratory. However, most students do not reach a satisfactory level of competence in the design of experimental approaches. This…

  20. A piezoelectric active sensing method for quantitative monitoring of bolt loosening using energy dissipation caused by tangential damping based on the fractal contact theory

    Science.gov (United States)

    Wang, Furui; Huo, Linsheng; Song, Gangbing

    2018-01-01

    Monitoring of bolt looseness is essential for ensuring the safety and reliability of equipment and structures with bolted connections. It is well known that tangential damping has an important influence on energy dissipation during wave propagation across the bolted joints, which require different levels of preload. In this paper, the energy dissipation generated by tangential damping of the bolted joints under different bolt preloads was modeled analytically based on fractal contact theory, which took the imperfect interface into account. A saturation value exists with the increase of the bolt preload, and the center frequency of emitted signal is demonstrated to affect the received energy significantly. Compared with previous similar studies based on experimental techniques and numerical method, the investigation presented in this paper explains the phenomenon from the inherent mechanism, and achieves the accurate quantitative monitoring of bolt looseness directly, rather than an indirect failure index. Finally, the validity of the proposed method in this paper was demonstrated with an experimental study of a bolted joint with different preload levels.

  1. Unified Analysis of Multi-Chamber Contact Tanks and Mixing Efficiency Based on Vorticity Field. Part I: Hydrodynamic Analysis

    Directory of Open Access Journals (Sweden)

    Ender Demirel

    2016-11-01

    Full Text Available Multi-chamber contact tanks have been extensively used in industry for water treatment to provide potable water to communities, which is essential for human health. To evaluate the efficiency of this treatment process, flow and tracer transport analysis have been used in the literature using Reynolds averaged Navier–Stokes (RANS and large-eddy simulations (LES. The purpose of this study is two-fold. First a unifying analysis of the flow field is presented and similarities and differences in the numerical results that were reported in the literature are discussed. Second, the vorticity field is identified as the key parameter to use in separating the mean flow (jet zone and the recirculating zones. Based on the concepts of vorticity gradient and flexion product, it is demonstrated that the separation of the recirculation zone and the jet zone, fluid-fluid flow separation, is possible. The separation of the recirculation zones and vortex core lines are characterized using the definition of the Lamb vector. The separated regions are used to characterize the mixing efficiency in the chambers of the contact tank. This analysis indicates that the recirculation zone and jet zone formation are three-dimensional and require simulations over a long period of time to reach stability. It is recognized that the characteristics of the jet zones and the recirculation zones are distinct for each chamber and they follow a particular pattern and symmetry between the alternating chambers. Hydraulic efficiency coefficients calculated for each chamber show that the chambers having an inlet adjacent to the free surface may be designed to have larger volumes than the chambers having wall bounded inlets to improve the efficiency of the contact tank. This is a simple design alternative that would increase the efficiency of the system. Other observations made through the chamber analysis are also informative in redefining the characteristics of the efficiency of the

  2. Data on face-to-face contacts in an office building suggests a low-cost vaccination strategy based on community linkers

    CERN Document Server

    Génois, Mathieu; Fournet, Julie; Panisson, André; Bonmarin, Isabelle; Barrat, Alain

    2014-01-01

    Empirical data on contacts between individuals in social contexts play an important role in the information of models describing human behavior and how epidemics spread in populations. Here, we analyze data on face-to-face contacts collected in an office building. The statistical properties of contacts are similar to other social situations, but important differences are observed in the contact network structure. In particular, the contact network is strongly shaped by the organization of the offices in departments, which has consequences in the design of accurate agent-based models of epidemic spread. We then consider the contact network as a potential substrate for infectious disease spread and show that its sparsity tends to prevent outbreaks of fast-spreading epidemics. Moreover, we define three typical behaviors according to the fraction $f$ of links each individual shares outside its own department: residents, wanderers and linkers. Linkers ($f\\sim 50%$) act as bridges in the network and have large betw...

  3. Telescopic vision contact lens

    Science.gov (United States)

    Tremblay, Eric J.; Beer, R. Dirk; Arianpour, Ashkan; Ford, Joseph E.

    2011-03-01

    We present the concept, optical design, and first proof of principle experimental results for a telescopic contact lens intended to become a visual aid for age-related macular degeneration (AMD), providing magnification to the user without surgery or external head-mounted optics. Our contact lens optical system can provide a combination of telescopic and non-magnified vision through two independent optical paths through the contact lens. The magnified optical path incorporates a telescopic arrangement of positive and negative annular concentric reflectors to achieve 2.8x - 3x magnification on the eye, while light passing through a central clear aperture provides unmagnified vision.

  4. Insulator-based dielectrophoresis of microorganisms: theoretical and experimental results.

    Science.gov (United States)

    Moncada-Hernandez, Hector; Baylon-Cardiel, Javier L; Pérez-González, Victor H; Lapizco-Encinas, Blanca H

    2011-09-01

    Dielectrophoresis (DEP) is the motion of particles due to polarization effects in nonuniform electric fields. DEP has great potential for handling cells and is a non-destructive phenomenon. It has been utilized for different cell analysis, from viability assessments to concentration enrichment and separation. Insulator-based DEP (iDEP) provides an attractive alternative to conventional electrode-based systems; in iDEP, insulating structures are used to generate nonuniform electric fields, resulting in simpler and more robust devices. Despite the rapid development of iDEP microdevices for applications with cells, the fundamentals behind the dielectrophoretic behavior of cells has not been fully elucidated. Understanding the theory behind iDEP is necessary to continue the progress in this field. This work presents the manipulation and separation of bacterial and yeast cells with iDEP. A computational model in COMSOL Multiphysics was employed to predict the effect of direct current-iDEP on cells suspended in a microchannel containing an array of insulating structures. The model allowed predicting particle behavior, pathlines and the regions where dielectrophoretic immobilization should occur. Experimental work was performed at the same operating conditions employed with the model and results were compared, obtaining good agreement. This is the first report on the mathematical modeling of the dielectrophoretic response of yeast and bacterial cells in a DC-iDEP microdevice. Copyright © 2011 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

  5. Experimental characterization of droplet dispensing in electrowetting-based microfluidics

    Science.gov (United States)

    Ahmadi, Mohammad Khorsand; Shokoohi, Mehrdad; Passandideh-Fard, Mohammad

    2017-07-01

    In this study, the effect of various parameters on the dispensed droplet size in microchannels based on the electrowetting on dielectric technique is experimentally investigated. A printed circuit board (PCB)-based microfluidic chip is used as a platform for the experiments. A crescent configuration for the channel electrodes is fabricated, which leads to a higher electrowetting force which improves the motion of the droplet. In addition, two electrode designs are proposed, which provide a nearly constant overlapping length on the reservoir electrode. The focus of this paper is on the geometry of the reservoir and the channel electrode; therefore, the channel dimensions, surface conditions, and applied voltage are kept constant. The experiments are performed for various reservoir liquid volumes and different electrode shapes of the reservoir and the microchannel. The results show that decreasing the length of the small reservoir electrode reduces the size of the dispensed droplet. It is also observed that using a channel electrode curved in the opposite direction of the droplet motion leads to a smaller dispensed droplet.

  6. Mechanical Contact Experiments and Simulations

    DEFF Research Database (Denmark)

    Nielsen, Chris Valentin; Martins, P; Zhang, W.

    2011-01-01

    Mechanical contact is studied under dynamic development by means of a combined numerical and experimental investigation. The experiments are designed to allow dynamical development of non-planar contact areas with significant expansion in all three directions as the load is increased. Different....... The overall investigation serves for testing and validating the numerical implementation of the mechanical contact, which is one of the main contributions to a system intended for 3D simulation of resistance welding. Correct modelling of contact between parts to be welded, as well as contact with electrodes......, is crucial for satisfactory modelling of the resistance welding process. The resistance heating at the contact interfaces depends on both contact area and pressure, and as the contact areas develop dynamically, the presented tests are relevant for assessing the validity and accuracy of the mechanical contact...

  7. Efficacy of a "contact center-based communication" in optimizing the care of inflammatory bowel diseases.

    Science.gov (United States)

    Castiglione, Fabiana; Imperatore, Nicola; Testa, Anna; Rea, Matilde; Nardone, Olga Maria; Gervetti, Paola; Taranto, Maria Laura; D'Onofrio, Gaetano; Caporaso, Nicola; Rispo, Antonio

    2016-08-01

    Telephone helplines are a useful vehicle for the management of chronic diseases even though data on how these can ease management of inflammatory bowel disease (IBD) is still scarce. to analyze our two-years' experience with the first telephone helpline dedicated to IBD in Italy. The main outcomes of using a contact center (CC) at our Unit were analyzed; all data was prospectively collected. Patients' requests were classified into medical or non-medical. The percentage of hospitalized patients in the pre-CC period was compared to that after CC activation, to assess the potential clinical gain of using CC. The calls were divided into 5 categories to evaluate a potential correlation between patients' number of calls and risk of hospitalization. The CC received 11,080 calls and handled 11,972 requests. In particular, 63% of patients phoned monthly for a medical consultation, and 37% called for non-medical reasons. In 2012, the followed-up patients were 1658 with 230 IBD-caused hospitalizations (14%); in 2014, the followed-up patients were 1962 with 182 hospitalizations (9%) (p30 calls (p<0.01). A dedicated CC could provide additional clinical gain, care, and support for IBD patients. Copyright © 2016 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.

  8. Exploring New Mechanisms for Effective Antimicrobial Materials: Electric Contact-Killing Based on Multiple Schottky Barriers.

    Science.gov (United States)

    de Lucas-Gil, Eva; Reinosa, Julián J; Neuhaus, Kerstin; Vera-Londono, Liliana; Martín-González, Marisol; Fernández, José F; Rubio-Marcos, Fernando

    2017-08-09

    The increasing threat of multidrug-resistance organisms is a cause for worldwide concern. Progressively microorganisms become resistant to commonly used antibiotics, which are a healthcare challenge. Thus, the discovery of new antimicrobial agents or new mechanisms different from those used is necessary. Here, we report an effective and selective antimicrobial activity of microstructured ZnO (Ms-ZnO) agent through the design of a novel star-shaped morphology, resulting in modulation of surface charge orientation. Specifically, we find that Ms-ZnO particles are composed of platelet stacked structure, which generates multiple Schottky barriers due to the misalignment of crystallographic orientations. We also demonstrated that this effect allows negative charge accumulation in localized regions of the structure to act as "charged domain walls", thereby improving the antimicrobial effectiveness by electric discharging effect. We use a combination of field emission scanning electron microscopy (FE-SEM), SEM-cathodoluminescence imaging, and Kelvin probe force microscopy (KPFM) to determine that the antimicrobial activity is a result of microbial membrane physical damage caused by direct contact with the Ms-ZnO agent. It is important to point out that Ms-ZnO does not use the photocatalysis or the Zn 2+ released as the main antimicrobial mechanism, so consequently this material would show low toxicity and robust stability. This approach opens new possibilities to understand both the physical interactions role as main antimicrobial mechanisms and insight into the coupled role of hierarchical morphologies and surface functionality on the antimicrobial activity.

  9. Potential contact and intraocular lenses based on hydrophilic/hydrophobic sulfonated syndiotactic polystyrene membranes

    Directory of Open Access Journals (Sweden)

    Simona Zuppolini

    2017-10-01

    Full Text Available Crystalline films of syndiotactic polystyrene (s-PS, a commercially available thermoplastic polymer, having a highly hydrophilic amorphous phase, were achieved by using a mild solid-state sulfonation procedure. Despite the used mild process conditions, an easy and uniform sulfonation of the phenyl rings of the amorphous phase is obtained. The crystallinity of the polymer was not affect by the sulfonation degree (S, at least at S less than 20%, and the obtained polymer films show the nanoporous crystalline form of s-PS. As widely reported in literature, the nanoporous nature of the polymer crystalline phase gives to these materials the ability to absorb and release organic molecules of appropriate size and polarity. This property, coupled to transparency, makes these materials potentially useful intraocular lens (IOLs and contact lens applications. Sulfonation procedure and sulfonated film samples characterization by using wide-angle X-ray diffraction (WAXD, Fourier-transform infrared (FTIR and ultraviolet-visible (UV-vis spectroscopy techniques and water sorption tests were reported. Furthermore, the biocompatibility study demonstrated no cytotoxicity and appropriate cell interaction properties for the specific applications.

  10. Research on vibration characteristics of gun barrel based on contact model

    Science.gov (United States)

    Zhao, Yang; Zhou, Qizheng; Yue, Pengfei

    2017-04-01

    In order to study vibration characteristics of the gun barrel under the action of moving projectile, the gun barrel is simplified to cross sectional cantilever beam such as Euler. Considering contact conditions of inertia effect and projectile with the gun barrel, the equation of lateral vibration of the gun barrel is established under the projectile-gun coupling effect; the modal analysis method is used to give the analytic solutions of equation series. The effect of the motion parameters the projectile on the vibration of gun barrel is discussed, and characteristics of vibration of gun barrel are further studied under two conditions of repeating and projectile with mass eccentricity. The research results show that reasonable control of the acceleration of the projectile in the gun bore, and reduction of projectile mass eccentricity can help reduce the muzzle vibration at the gun firing. The research results can provide reference for overall design of the gun, and the modeling and analysis method used in the paper can be promoted for the solution of vibration of other related projects under the moving excitation.

  11. Contact-based model for strategy updating and evolution of cooperation

    Science.gov (United States)

    Zhang, Jianlei; Chen, Zengqiang

    2016-06-01

    To establish an available model for the astoundingly strategy decision process of players is not easy, sparking heated debate about the related strategy updating rules is intriguing. Models for evolutionary games have traditionally assumed that players imitate their successful partners by the comparison of respective payoffs, raising the question of what happens if the game information is not easily available. Focusing on this yet-unsolved case, the motivation behind the work presented here is to establish a novel model for the updating of states in a spatial population, by detouring the required payoffs in previous models and considering much more players' contact patterns. It can be handy and understandable to employ switching probabilities for determining the microscopic dynamics of strategy evolution. Our results illuminate the conditions under which the steady coexistence of competing strategies is possible. These findings reveal that the evolutionary fate of the coexisting strategies can be calculated analytically, and provide novel hints for the resolution of cooperative dilemmas in a competitive context. We hope that our results have disclosed new explanations about the survival and coexistence of competing strategies in structured populations.

  12. Injury Based on Its Study in Experimental Models

    Directory of Open Access Journals (Sweden)

    M. Mendes-Braz

    2012-01-01

    Full Text Available The present review focuses on the numerous experimental models used to study the complexity of hepatic ischemia/reperfusion (I/R injury. Although experimental models of hepatic I/R injury represent a compromise between the clinical reality and experimental simplification, the clinical transfer of experimental results is problematic because of anatomical and physiological differences and the inevitable simplification of experimental work. In this review, the strengths and limitations of the various models of hepatic I/R are discussed. Several strategies to protect the liver from I/R injury have been developed in animal models and, some of these, might find their way into clinical practice. We also attempt to highlight the fact that the mechanisms responsible for hepatic I/R injury depend on the experimental model used, and therefore the therapeutic strategies also differ according to the model used. Thus, the choice of model must therefore be adapted to the clinical question being answered.

  13. Cultivating engineering innovation ability based on optoelectronic experimental platform

    Science.gov (United States)

    Li, Dangjuan; Wu, Shenjiang

    2017-08-01

    As the supporting experimental platform of the Xi'an Technological University education reform experimental class, "optical technological innovation experimental platform" integrated the design and comprehensive experiments of the optical multi-class courses. On the basis of summing up the past two years teaching experience, platform pilot projects were improve. It has played a good role by making the use of an open teaching model in the cultivating engineering innovation spirit and scientific thinking of the students.

  14. EDITORIAL: Close contact Close contact

    Science.gov (United States)

    Demming, Anna

    2010-07-01

    The development of scanning probe techniques, such as scanning tunnelling microscopy [1], has often been touted as the catalyst for the surge in activity and progress in nanoscale science and technology. Images of nanoscale structural detail have served as an invaluable investigative resource and continue to fascinate with the fantastical reality of an intricate nether world existing all around us, but hidden from view of the naked eye by a disparity in scale. As is so often the case, the invention of the scanning tunnelling microscope heralded far more than just a useful new apparatus, it demonstrated the scope for exploiting the subtleties of electronic contact. The shrinking of electronic devices has been a driving force for research into molecular electronics, in which an understanding of the nature of electronic contact at junctions is crucial. In response, the number of experimental techniques in molecular electronics has increased rapidly in recent years. Scanning tunnelling microscopes have been used to study electron transfer through molecular films on a conducting substrate, and the need to monitor the contact force of scanning tunnelling electrodes led to the use of atomic force microscopy probes coated in a conducting layer as studied by Cui and colleagues in Arizona [2]. In this issue a collaboration of researchers at Delft University and Leiden University in the Netherlands report a new device architecture for the independent mechanical and electrostatic tuning of nanoscale charge transport, which will enable thorough studies of molecular transport in the future [3]. Scanning probes can also be used to pattern surfaces, such as through spatially-localized Suzuki and Heck reactions in chemical scanning probe lithography. Mechanistic aspects of spatially confined Suzuki and Heck chemistry are also reported in this issue by researchers in Oxford [4]. All these developments in molecular electronics fabrication and characterization provide alternative

  15. A study of effects of electrode contacts on performance of organic-based light-emitting field-effect transistors

    Science.gov (United States)

    Kim, Dae-Kyu; Choi, Jong-Ho

    2018-02-01

    Herein is presented a comparative performance analysis of heterojunction organic-based light-emitting field-effect transistors (OLEFETs) with symmetric (Au only) and asymmetric (Au and LiF/Al) electrode contacts. The devices had a top source-drain contact with long-channel geometry and were produced by sequentially depositing p-type pentacene and n-type N,N‧-ditridecylperylene-3,4,9,10-tetracarboxylic diimide (P13) using a neutral cluster beam deposition apparatus. The spectroscopic, structural and morphological properties of the organic thin films were examined using photoluminescence (PL) spectroscopy, X-ray diffraction (XRD) method, laser scanning confocal and atomic force microscopy (LSCM, AFM). Based upon the growth of high-quality, well-packed crystalline thin films, the devices demonstrated ambipolar field-effect characteristics, stress-free operational stability, and light emission under ambient conditions. Various device parameters were derived from the fits of the observed characteristics. The hole mobilities were nearly equal irrespective of the electrode contacts, whereas the electron mobilities of the transistors with LiF/Al drain electrodes were higher due to the low injection barrier. For the OLEFETs with symmetric electrodes, electroluminescence (EL) occurred only in the vicinity of the hole-injecting electrode, whereas for the OLEFETs with asymmetric electrodes, the emission occurred in the vicinity of both hole- and electron-injecting electrodes. By tuning the carrier injection and transport through high- and low-work function metals, the hole-electron recombination sites could be controlled. The operating conduction and light emission mechanism are discussed with the aid of EL images obtained using a charge-coupled device (CCD) camera.

  16. First Contact: interprofessional education based on medical students' experiences from their nursing internship

    Directory of Open Access Journals (Sweden)

    Eich-Krohm, Astrid

    2016-04-01

    Full Text Available Goal: The aim of the course “interprofessional communication and nursing” is to reflect medical students’ experiences from the nursing internship. The content of the course focuses on barriers and support of interprofessional communication as a foundation for teamwork between nursing professionals and physicians. The nursing internship is for most medical students the first contact with nursing professionals and can lead to perceptions about the other group that might hinder interprofessional teamwork and consequently harm patients. To meet the demographic challenges ahead it is important to emphasize interprofessional education in the study of medicine and better prepare future physicians for interprofessional collaboration. Method: The design of the course includes an assessment of a change in the students’ perceptions about nursing and interprofessional communication. The first class meeting presents the starting point of the assessment and visualizes students’ perceptions of nursing and medicine. The content of the following class meetings serve to enhance the students’ knowledge about nursing as a profession with its own theories, science and scholarship. In addition, all students have to write a research paper that entails to interview one nursing professional and one physician about their ideas of interprofessional communication and to compare the interviews with their own experiences from the nursing internship. To access what students learned during the course a reflective discussion takes place at the last meeting combined with an analysis of the students’ research papers. Results: The assessment of the students’ perceptions about the nursing profession and the importance of successful interprofessional communication showed a new and deeper understanding of the topic. They were able to identify barriers and support measures of interprofessional communication and their own responsibilities as part of a team

  17. Experimental teaching and training system based on volume holographic storage

    Science.gov (United States)

    Jiang, Zhuqing; Wang, Zhe; Sun, Chan; Cui, Yutong; Wan, Yuhong; Zou, Rufei

    2017-08-01

    The experiment of volume holographic storage for teaching and training the practical ability of senior students in Applied Physics is introduced. The students can learn to use advanced optoelectronic devices and the automatic control means via this experiment, and further understand the theoretical knowledge of optical information processing and photonics disciplines that have been studied in some courses. In the experiment, multiplexing holographic recording and readout is based on Bragg selectivity of volume holographic grating, in which Bragg diffraction angle is dependent on grating-recording angel. By using different interference angle between reference and object beams, the holograms can be recorded into photorefractive crystal, and then the object images can be read out from these holograms via angular addressing by using the original reference beam. In this system, the experimental data acquisition and the control of the optoelectronic devices, such as the shutter on-off, image loaded in SLM and image acquisition of a CCD sensor, are automatically realized by using LabVIEW programming.

  18. P300-based brain computer interface experimental setup.

    Science.gov (United States)

    Arboleda, Carolina; Garcia, Eliana; Posada, Alejandro; Torres, Robinson

    2009-01-01

    A Brain-Computer interface (BCI) is a communication system that enables the generation of a control signal from brain signals such as sensorymotor rhythms and evoked potentials; therefore, it constitutes a novel communication option for people with severe motor disabilities (such as Amyotrophic Lateral Sclerosis patients). This paper presents the development of a P300-based BCI. This prototype uses a homemade six-channel electroencephalograph for the acquisition of the signals, and a visual stimulation matrix; since this matrix contains letters of the alphabet as well as images associated to them, it permits word-writing and the elaboration of messages with the images. To process the signals the software BCI2000 and MATLAB 7.0 were used. The latter was used to program three linear translation algorithms (Stepwise Linear Discriminant Analysis, Lineal Discriminant Analysis and Least Squares) to convert the brain signals into communication signals. These algorithms had a classification accuracy of 90.73 %, 95.75 % and 89.45 % respectively, when using raw data; and of 90.78%, 49.48 % and 53.9 %, when data was previously common-average filtered. The experimental setup was tested in ten healthy volunteers; 5 of them got a 100% success, 1 a 90% success, 2 an around 70% success and 2 a 50% success, in the online free-spelling tests.

  19. Experimental stability analysis of different water-based nanofluids

    Directory of Open Access Journals (Sweden)

    Barison Simona

    2011-01-01

    Full Text Available Abstract In the recent years, great interest has been devoted to the unique properties of nanofluids. The dispersion process and the nanoparticle suspension stability have been found to be critical points in the development of these new fluids. For this reason, an experimental study on the stability of water-based dispersions containing different nanoparticles, i.e. single wall carbon nanohorns (SWCNHs, titanium dioxide (TiO2 and copper oxide (CuO, has been developed in this study. The aim of this study is to provide stable nanofluids for selecting suitable fluids with enhanced thermal characteristics. Different dispersion techniques were considered in this study, including sonication, ball milling and high-pressure homogenization. Both the dispersion process and the use of some dispersants were investigated as a function of the nanoparticle concentration. The high-pressure homogenization was found to be the best method, and the addition of n-dodecyl sulphate and polyethylene glycol as dispersants, respectively in SWCNHs-water and TiO2-water nanofluids, improved the nanofluid stability.

  20. Reform of experimental teaching based on quality cultivation

    Science.gov (United States)

    Wang, Wei; Yan, Xingwei; Liu, Wei; Yao, Tianfu; Shi, Jianhua; Lei, Bing; Hu, Haojun

    2017-08-01

    Experimental teaching plays an import part in quality education which devotes to cultivating students with innovative spirit, strong technological talents and practical ability. However, in the traditional experimental teaching mode, the experiments are treated as a vassal or supplementary mean of theoretical teaching, and students prefer focus on theory to practice. Therefore, the traditional experimental teaching mode is difficult to meet the requirements of quality education. To address this issue, the reform of experimental teaching is introduced in this paper taking the photoelectric detector experiment as the example. The new experimental teaching mode is designed from such aspects as experimental content, teaching method and experimental evaluation. With the purpose of cultivating students' practical ability, two different-level experimental content is designed. Not only the basic experiments used to verify the theory are set to consolidate the students' learned theoretical knowledge, but also comprehensive experiments are designed to encourage the students to apply their learned knowledge to solve practical problems. In the teaching process, heuristic teaching thought is adopt and the traditional `teacher-centered' teaching form is replaced by `student-centered' form, which aims to encourage students to design the experimental systems by their own with the teacher's guidance. In addition to depending on stimulating the students' interest of science research, experimental evaluation is necessary to urge students to complete the experiments efficiently. Multifaceted evaluation method is proposed to test the students' mastery of theoretical knowledge, practice ability, troubleshooting and problem solving skills, and innovation capability comprehensively. Practices demonstrated the satisfying effect of our experimental teaching mode.

  1. Experimental Fuels Facility Re-categorization Based on Facility Segmentation

    Energy Technology Data Exchange (ETDEWEB)

    Reiss, Troy P.; Andrus, Jason

    2016-07-01

    The Experimental Fuels Facility (EFF) (MFC-794) at the Materials and Fuels Complex (MFC) located on the Idaho National Laboratory (INL) Site was originally constructed to provide controlled-access, indoor storage for radiological contaminated equipment. Use of the facility was expanded to provide a controlled environment for repairing contaminated equipment and characterizing, repackaging, and treating waste. The EFF facility is also used for research and development services, including fuel fabrication. EFF was originally categorized as a LTHC-3 radiological facility based on facility operations and facility radiological inventories. Newly planned program activities identified the need to receive quantities of fissionable materials in excess of the single parameter subcritical limit in ANSI/ANS-8.1, “Nuclear Criticality Safety in Operations with Fissionable Materials Outside Reactors” (identified as “criticality list” quantities in DOE-STD-1027-92, “Hazard Categorization and Accident Analysis Techniques for Compliance with DOE Order 5480.23, Nuclear Safety Analysis Reports,” Attachment 1, Table A.1). Since the proposed inventory of fissionable materials inside EFF may be greater than the single parameter sub-critical limit of 700 g of U-235 equivalent, the initial re-categorization is Hazard Category (HC) 2 based upon a potential criticality hazard. This paper details the facility hazard categorization performed for the EFF. The categorization was necessary to determine (a) the need for further safety analysis in accordance with LWP-10802, “INL Facility Categorization,” and (b) compliance with 10 Code of Federal Regulations (CFR) 830, Subpart B, “Safety Basis Requirements.” Based on the segmentation argument presented in this paper, the final hazard categorization for the facility is LTHC-3. Department of Energy Idaho (DOE-ID) approval of the final hazard categorization determined by this hazard assessment document (HAD) was required per the

  2. A New Method to Detect Driver Fatigue Based on EMG and ECG Collected by Portable Non-Contact Sensors

    Directory of Open Access Journals (Sweden)

    Lin Wang

    2017-11-01

    Full Text Available Recently, detection and prediction on driver fatigue have become interest of research worldwide. In the present work, a new method is built to effectively evaluate driver fatigue based on electromyography (EMG and electrocardiogram (ECG collected by portable real-time and non-contact sensors. First, under the non-disturbance condition for driver’s attention, mixed physiological signals (EMG, ECG and artefacts are collected by non-contact sensors located in a cushion on the driver’s seat. EMG and ECG are effectively separated by FastICA, and de-noised by empirical mode decomposition (EMD. Then, three physiological features, complexity of EMG, complexity of ECG, and sample entropy (SampEn of ECG, are extracted and analysed. Principal components are obtained by principal components analysis (PCA and are used as independent variables. Finally, a mathematical model of driver fatigue is built, and the accuracy of the model is up to 91%. Moreover, based on the questionnaire, the calculation results of model are consistent with real fatigue felt by the participants. Therefore, this model can effectively detect driver fatigue.

  3. Exploring the Nature of Contact Freezing

    Science.gov (United States)

    Kiselev, A. A.; Hoffmann, N.; Duft, D.; Leisner, T.

    2012-12-01

    The freezing of supercooled water droplets upon contact with aerosol particles (contact nucleation of ice) is the least understood mechanism of ice formation in atmospheric clouds. Although experimental evidences suggest that some aerosols can be better IN in the contact than in the immersion mode (that is, triggering ice nucleation at higher temperature), no final explanation of this phenomena currently exists. On the other hand, the contact freezing is believed to be responsible for the enhanced rate of secondary ice formation occasionally observed in LIDAR measurements in the cold mixed phase clouds. Recently we have been able to show that the freezing of supercooled droplets electrodynamically levitated in the laminar flow containing mineral dust particles (kaolinite) is a process solely governed by a rate of collisions between the supercooled droplet and the aerosol particles. We have shown that the probability of droplet freezing on a single contact with aerosol particle may differ over an order of magnitude for kaolinite particles having different genesis and morphology. In this presentation we extend the study of contact nucleation of ice and compare the IN efficiency measured for DMA-selected kaolinite, illite and hematite particles. We show that the freezing probability increases towards unity as the temperature decreases and discuss the functional form of this temperature dependence. We explore the size dependence of the contact freezing probability and show that it scales with the surface area of the particles, thus resembling the immersion freezing behavior. However, for all minerals investigated so far, the contact freezing has been shown to dominate over immersion freezing on the short experimental time scales. Finally, based on the combined ESEM and electron microprobe analysis, we discuss the significance of particle morphology and variability of chemical composition on its IN efficiency in contact mode.

  4. The effect of silicone hydrogel bandage soft contact lens base curvature on comfort and outcomes after photorefractive keratectomy.

    Science.gov (United States)

    Taylor, Kenneth R; Molchan, Ryan P; Townley, J Richard; Caldwell, Matthew C; Panday, Vasudha A

    2015-03-01

    To evaluate the relative pain and the relative amount of contact lens loss experienced using two different base curvatures (BCs) of the Acuvue Oasys bandage soft contact lens (BSCL) after photorefractive keratectomy (PRK). One hundred forty patients undergoing PRK on either the Allegretto or the VISX laser at the Joint Warfighter Refractive Surgery Center in Lackland AFB, TX, were randomized to one of the two different BCs of the Acuvue Oasys BSCL: 8.4 or 8.8 mm. Patients were evaluated on postoperative days 1 and 4 during which they completed a survey rating absolute pain in each eye on a visual analog pain scale. Lens loss was recorded throughout the study. Patients treated on the Allegretto laser preferred the 8.4-mm BC lens, whereas comfort after treatment on the VISX depended on corneal shape. For VISX, patients with very flat corneas (steep K ≤42 preoperative or ≤38 postoperatively) preferred an 8.8-mm BC lens while patients with very steep corneas (steep K >45 preoperative or >42 postoperative) preferred an 8.4-mm BC lens, though these results were largely not statistically significant. Patients who lost their lenses prematurely tended to be those whose corneal curvature did not match their contact lens BC. Individuals treated with the Allegretto laser or individuals with more prolate corneas should likely be fit with an 8.4-mm BC Acuvue Oasys BSCL while individuals with more oblate corneas should likely be fit with an 8.8-mm BC lens to minimize postoperative pain and premature BSCL loss.

  5. Pattern of contact sensitization in patients with and without atopic dermatitis in a hospital-based clinical database

    DEFF Research Database (Denmark)

    Clemmensen, Kim Katrine Bjerring; Thomsen, Simon Francis; Jemec, Gregor Borut Ernst

    2014-01-01

    BACKGROUND: Both atopic dermatitis and contact sensitization are common conditions; however, a definite understanding of the relationship between contact sensitization and atopic dermatitis has not been reached. OBJECTIVES: In this descriptive study, we investigated the differences between positi...

  6. Sensing with Superconducting Point Contacts

    Directory of Open Access Journals (Sweden)

    Argo Nurbawono

    2012-05-01

    Full Text Available Superconducting point contacts have been used for measuring magnetic polarizations, identifying magnetic impurities, electronic structures, and even the vibrational modes of small molecules. Due to intrinsically small energy scale in the subgap structures of the supercurrent determined by the size of the superconducting energy gap, superconductors provide ultrahigh sensitivities for high resolution spectroscopies. The so-called Andreev reflection process between normal metal and superconductor carries complex and rich information which can be utilized as powerful sensor when fully exploited. In this review, we would discuss recent experimental and theoretical developments in the supercurrent transport through superconducting point contacts and their relevance to sensing applications, and we would highlight their current issues and potentials. A true utilization of the method based on Andreev reflection analysis opens up possibilities for a new class of ultrasensitive sensors.

  7. Contact materials for nanoelectronics

    KAUST Repository

    Alshareef, Husam N.

    2011-02-01

    In this article, we review current research activities in contact material development for electronic and nanoelectronic devices. A fundamental issue in contact materials research is to understand and control interfacial reactions and phenomena that modify the expected device performance. These reactions have become more challenging and more difficult to control as new materials have been introduced and as device sizes have entered the deep nanoscale. To provide an overview of this field of inquiry, this issue of MRS Bulletin includes articles on gate and contact materials for Si-based devices, junction contact materials for Si-based devices, and contact materials for alternate channel substrates (Ge and III-V), nanodevices. © 2011 Materials Research Society.

  8. Estimates of Social Contact in a Middle School Based on Self-Report and Wireless Sensor Data.

    Science.gov (United States)

    Leecaster, Molly; Toth, Damon J A; Pettey, Warren B P; Rainey, Jeanette J; Gao, Hongjiang; Uzicanin, Amra; Samore, Matthew

    2016-01-01

    Estimates of contact among children, used for infectious disease transmission models and understanding social patterns, historically rely on self-report logs. Recently, wireless sensor technology has enabled objective measurement of proximal contact and comparison of data from the two methods. These are mostly small-scale studies, and knowledge gaps remain in understanding contact and mixing patterns and also in the advantages and disadvantages of data collection methods. We collected contact data from a middle school, with 7th and 8th grades, for one day using self-report contact logs and wireless sensors. The data were linked for students with unique initials, gender, and grade within the school. This paper presents the results of a comparison of two approaches to characterize school contact networks, wireless proximity sensors and self-report logs. Accounting for incomplete capture and lack of participation, we estimate that "sensor-detectable", proximal contacts longer than 20 seconds during lunch and class-time occurred at 2 fold higher frequency than "self-reportable" talk/touch contacts. Overall, 55% of estimated talk-touch contacts were also sensor-detectable whereas only 15% of estimated sensor-detectable contacts were also talk-touch. Contacts detected by sensors and also in self-report logs had longer mean duration than contacts detected only by sensors (6.3 vs 2.4 minutes). During both lunch and class-time, sensor-detectable contacts demonstrated substantially less gender and grade assortativity than talk-touch contacts. Hallway contacts, which were ascertainable only by proximity sensors, were characterized by extremely high degree and short duration. We conclude that the use of wireless sensors and self-report logs provide complementary insight on in-school mixing patterns and contact frequency.

  9. Estimates of Social Contact in a Middle School Based on Self-Report and Wireless Sensor Data.

    Directory of Open Access Journals (Sweden)

    Molly Leecaster

    Full Text Available Estimates of contact among children, used for infectious disease transmission models and understanding social patterns, historically rely on self-report logs. Recently, wireless sensor technology has enabled objective measurement of proximal contact and comparison of data from the two methods. These are mostly small-scale studies, and knowledge gaps remain in understanding contact and mixing patterns and also in the advantages and disadvantages of data collection methods. We collected contact data from a middle school, with 7th and 8th grades, for one day using self-report contact logs and wireless sensors. The data were linked for students with unique initials, gender, and grade within the school. This paper presents the results of a comparison of two approaches to characterize school contact networks, wireless proximity sensors and self-report logs. Accounting for incomplete capture and lack of participation, we estimate that "sensor-detectable", proximal contacts longer than 20 seconds during lunch and class-time occurred at 2 fold higher frequency than "self-reportable" talk/touch contacts. Overall, 55% of estimated talk-touch contacts were also sensor-detectable whereas only 15% of estimated sensor-detectable contacts were also talk-touch. Contacts detected by sensors and also in self-report logs had longer mean duration than contacts detected only by sensors (6.3 vs 2.4 minutes. During both lunch and class-time, sensor-detectable contacts demonstrated substantially less gender and grade assortativity than talk-touch contacts. Hallway contacts, which were ascertainable only by proximity sensors, were characterized by extremely high degree and short duration. We conclude that the use of wireless sensors and self-report logs provide complementary insight on in-school mixing patterns and contact frequency.

  10. Elastic contact mechanics: percolation of the contact area and fluid squeeze-out.

    Science.gov (United States)

    Persson, B N J; Prodanov, N; Krick, B A; Rodriguez, N; Mulakaluri, N; Sawyer, W G; Mangiagalli, P

    2012-01-01

    The dynamics of fluid flow at the interface between elastic solids with rough surfaces depends sensitively on the area of real contact, in particular close to the percolation threshold, where an irregular network of narrow flow channels prevails. In this paper, numerical simulation and experimental results for the contact between elastic solids with isotropic and anisotropic surface roughness are compared with the predictions of a theory based on the Persson contact mechanics theory and the Bruggeman effective medium theory. The theory predictions are in good agreement with the experimental and numerical simulation results and the (small) deviation can be understood as a finite-size effect. The fluid squeeze-out at the interface between elastic solids with randomly rough surfaces is studied. We present results for such high contact pressures that the area of real contact percolates, giving rise to sealed-off domains with pressurized fluid at the interface. The theoretical predictions are compared to experimental data for a simple model system (a rubber block squeezed against a flat glass plate), and for prefilled syringes, where the rubber plunger stopper is lubricated by a high-viscosity silicon oil to ensure functionality of the delivery device. For the latter system we compare the breakloose (or static) friction, as a function of the time of stationary contact, to the theory prediction.

  11. Dualism-Based Design of the Introductory Chinese MOOC "Kit de contact en langue chinoise"

    Science.gov (United States)

    Wang-Szilas, Jue; Bellassen, Joël

    2017-01-01

    This article reviews the existing Chinese language Massive Open Online Courses (MOOCs) and points out three problems in their design: the monism-based teaching method, the non-integration of cultural elements, and the lack of learner-learner interactions. It then presents the design principles of the Introductory Chinese MOOC in an attempt to…

  12. Testing homology with CAO: A contact-based Markov model of protein evolution.

    NARCIS (Netherlands)

    Lin, K.; Kleinjung, J.; Taylor, W.; Heringa, J.

    2003-01-01

    Point Accepted Mutation (PAM) is the Markov model of amino acid replacements in proteins introduced by Dayhoff and her co-workers (Dayhoff et al., 1978). The PAM matrices and other matrices based on the PAM model have been widely accepted as the standard scoring system of protein sequence similarity

  13. Nanolithography based contacting method for electrical measurements on single template synthesized nanowires

    DEFF Research Database (Denmark)

    Fusil, S.; Piraux, L.; Mátéfi-Tempfli, Stefan

    2005-01-01

    A reliable method enabling electrical measurements on single nanowires prepared by electrodeposition in an alumina template is described. This technique is based on electrically controlled nanoindentation of a thin insulating resist deposited on the top face of the template filled by the nanowires...

  14. Effects of skin-to-skin contact and breastfeeding at birth on the incidence of PPH: A physiologically based theory.

    Science.gov (United States)

    Saxton, Anne; Fahy, Kathleen; Hastie, Carolyn

    2014-12-01

    The importance of optimising maternal/baby psychophysiology has been integrated into contemporary midwifery theories but not in the detail required to really understand the underpinning biological basis. The functioning of the autonomic nervous system, as it relates to the uterus is reviewed. The physiology of myometrial cell contraction and relaxation is outlined. The main focus is on the factors that affect the availability and uptake of oxytocin and adrenaline/noradrenaline in the myometrial cells. These are the two key neuro-hormones, active in the 3rd and 4th stages of labour, that affect uterine contraction and retraction and therefore determine whether the woman will have an atonic PPH or not. The discussion explains and predicts the physiological functioning of the uterus during the 3rd and 4th stages of labour when skin-to-skin contact and breastfeeding occurs and when it does not. This biologically based theory hypothesises that to achieve and maintain eutony and eulochia, midwives and birthing women should ensure early, prolonged and undisturbed skin-to-skin contact for mother and baby at birth including easy access for spontaneous breastfeeding. Copyright © 2014 Australian College of Midwives. Published by Elsevier Ltd. All rights reserved.

  15. Visible spectrum-based non-contact HRV and dPTT for stress detection

    Science.gov (United States)

    Kaur, Balvinder; Hutchinson, J. Andrew; Ikonomidou, Vasiliki N.

    2017-05-01

    Stress is a major health concern that not only compromises our quality of life, but also affects our physical health and well-being. Despite its importance, our ability to objectively detect and quantify it in a real-time, non-invasive manner is very limited. This capability would have a wide variety of medical, military, and security applications. We have developed a pipeline of image and signal processing algorithms to make such a system practical, which includes remote cardiac pulse detection based on visible spectrum videos and physiological stress detection based on the variability in the remotely detected cardiac signals. First, to determine a reliable cardiac pulse, principal component analysis (PCA) was applied for noise reduction and independent component analysis (ICA) was applied for source selection. To determine accurate cardiac timing for heart rate variability (HRV) analysis, a blind source separation method based least squares (LS) estimate was used to determine signal peaks that were closely related to R-peaks of the electrocardiogram (ECG) signal. A new metric, differential pulse transit time (dPTT), defined as the difference in arrival time of the remotely acquired cardiac signal at two separate distal locations, was derived. It was demonstrated that the remotely acquired metrics, HRV and dPTT, have potential for remote stress detection. The developed algorithms were tested against human subject data collected under two physiological conditions using the modified Trier Social Stress Test (TSST) and the Affective Stress Response Test (ASRT). This research provides evidence that the variability in remotely-acquired blood wave (BW) signals can be used for stress (high and mild) detection, and as a guide for further development of a real-time remote stress detection system based on remote HRV and dPTT.

  16. Contact Center Manager Administration (CCMA)

    Data.gov (United States)

    Social Security Administration — CCMA is the server that provides a browser-based tool for contact center administrators and supervisors. It is used to manage and configure contact center resources...

  17. Recent Advancements in Fractal Geometric-Based Nonlinear Time Series Solutions to the Micro-Quasistatic Thermoviscoelastic Creep for Rough Surfaces in Contact

    Directory of Open Access Journals (Sweden)

    Osama M. Abuzeid

    2011-01-01

    Full Text Available To understand the tripological contact phenomena, both mathematical and experimental models are needed. In this work, fractal mathematical models are used to model the experimental results obtained from literature. Fractal geometry, using a deterministic Cantor structure, is used to model the surface topography, where recent advancements in thermoviscoelastic creep contact of rough surfaces are introduced. Various viscoelastic idealizations are used to model the surface materials, for example, Maxwell, Kelvin-Voigt, Standard Linear Solid and Jeffrey media. Such media are modelled as arrangements of elastic springs and viscous dashpots in parallel and/or in series. Asymptotic power laws, through hypergeometric series, were used to express the surface creep as a function of remote forces, body temperatures and time. The introduced models are valid only when the creep approach of the contact surfaces is in the order of the size of the surface roughness. The obtained results using such models, which admit closed-form solutions, are displayed graphically for selected values of the systems' parameters; the fractal surface roughness and various material properties. Results obtained showed good agreement with published experimental results, where the utilized methodology can be further extended to the utilization for the contact of surfaces within micro- and nano-electronic devices, circuits and systems.

  18. Differential Laser Doppler based Non-Contact Sensor for Dimensional Inspection with Error Propagation Evaluation

    Directory of Open Access Journals (Sweden)

    Ketsaya Vacharanukul

    2006-06-01

    Full Text Available To achieve dynamic error compensation in CNC machine tools, a non-contactlaser probe capable of dimensional measurement of a workpiece while it is being machinedhas been developed and presented in this paper. The measurements are automatically fedback to the machine controller for intelligent error compensations. Based on a well resolvedlaser Doppler technique and real time data acquisition, the probe delivers a very promisingdimensional accuracy at few microns over a range of 100 mm. The developed opticalmeasuring apparatus employs a differential laser Doppler arrangement allowing acquisitionof information from the workpiece surface. In addition, the measurements are traceable tostandards of frequency allowing higher precision.

  19. Design of electronic devices based on carbon nanotubes heterojunction contacts to Zn ring layers

    Directory of Open Access Journals (Sweden)

    A Shokri

    2017-09-01

    Full Text Available In recent years, due to electron transport properties of nanostructures based on carbon nanotubes, a lot of attention to design electronic devices in the field of nanotechnology has attracted. There are three types of carbon nanotubes in zigzag, armchair and chiral (asymmetrical forms. Since the types of armchair are electrically conductive, by a combination with a metal such as zinc can be achieved by various means distinct applications. In this respect, we select different layers of circular connectors on the number of atoms of 10, 20 and 30, respectively, in the systems A-Zn10-A, A-Zn20-A and A-Zn30-A, where (A: armchair. Our calculations are based on the Green's function method within tight-binding approximation in the nearest neighbors in the framework of Landauer. The results are able to predict that devices with different functions such as quantum conductor wire, negative differential resistance and rectifier design. The results may be useful in the design of electronic devices at the nanometer scale.

  20. Fabrication of four-point biped robot foot module based on contact-resistance force sensor and its evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Kwon, Hyun Joon; Kim, Jong Ho; Kim, Dong Ki [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of); Kwon, Young Ha [Kyung Hee University, Yongin (Korea, Republic of)

    2011-02-15

    This paper presents the design of robot foot module of four-point biped walking robot and its fabrication. The foot module has four sensor units based on contact-resistance force sensor. The thin-film-type force sensor is fabricated by coating resistive ink on thin polyimide film using silk screening technique. The simple structure is devised and fabricated to assemble the thin force sensor rigidly. The unit force sensor module is evaluated by the calibration setup to obtain the characteristics of repeatability and hysteresis. The sensor module presents hysteresis error of about 5% and repeatability error of about 0.37%. The calculated zero moment point (ZMP) of the foot module is also compared with the measured position using static load of 50 N. The maximum location error of ZMP is less than 10%. The robot foot module shows the possibility of applying it to humanoid walking.

  1. Endocavitary thermal therapy by MRI-guided phased-array contact ultrasound: experimental and numerical studies on the multi-input single-output PID temperature controller's convergence and stability.

    Science.gov (United States)

    Salomir, Rares; Rata, Mihaela; Cadis, Daniela; Petrusca, Lorena; Auboiroux, Vincent; Cotton, François

    2009-10-01

    Endocavitary high intensity contact ultrasound (HICU) may offer interesting therapeutic potential for fighting localized cancer in esophageal or rectal wall. On-line MR guidance of the thermotherapy permits both excellent targeting of the pathological volume and accurate preoperatory monitoring of the temperature elevation. In this article, the authors address the issue of the automatic temperature control for endocavitary phased-array HICU and propose a tailor-made thermal model for this specific application. The convergence and stability of the feedback loop were investigated against tuning errors in the controller's parameters and against input noise, through ex vivo experimental studies and through numerical simulations in which nonlinear response of tissue was considered as expected in vivo. An MR-compatible, 64-element, cooled-tip, endorectal cylindrical phased-array applicator of contact ultrasound was integrated with fast MR thermometry to provide automatic feedback control of the temperature evolution. An appropriate phase law was applied per set of eight adjacent transducers to generate a quasiplanar wave, or a slightly convergent one (over the circular dimension). A 2D physical model, compatible with on-line numerical implementation, took into account (1) the ultrasound-mediated energy deposition, (2) the heat diffusion in tissue, and (3) the heat sink effect in the tissue adjacent to the tip-cooling balloon. This linear model was coupled to a PID compensation algorithm to obtain a multi-input single-output static-tuning temperature controller. Either the temperature at one static point in space (situated on the symmetry axis of the beam) or the maximum temperature in a user-defined ROI was tracked according to a predefined target curve. The convergence domain in the space of controller's parameters was experimentally explored ex vivo. The behavior of the static-tuning PID controller was numerically simulated based on a discrete-time iterative solution

  2. Electrical, Chemical, And Microstructural Analysis of the Thermal Stability of Nickel-based Ohmic Contacts to Silicon Carbide for High-Temperature Electronics

    Science.gov (United States)

    Virshup, Ariel R.

    With increasing attention on curbing the emission of pollutants into the atmosphere, chemical sensors that can be used to monitor and control these unwanted emissions are in great demand. Examples include monitoring of hydrocarbons from automobile engines and monitoring of flue gases such as CO emitted from power plants. One of the critical limitations in high-temperature SiC gas sensors, however, is the degradation of the metal-SiC contacts over time. In this dissertation, we investigated the high-temperature stability of Pt/TaSix/Ni/SiC ohmic contacts, which have been implemented in SiC-based gas sensors developed for applications in diesel engines and power plants. The high-temperature stability of a Pt/TaSi2/Ni/SiC ohmic contact metallization scheme was characterized using a combination of current-voltage measurements, Auger electron spectroscopy, secondary ion mass spectrometry, and transmission electron microscope imaging and associated analytical techniques. Increasing the thicknesses of the Pt and TaSi2 layers promoted electrical stability of the contacts, which remained ohmic at 600°C in air for over 300 h; the specific contact resistance showed only a gradual increase from an initial value of 5.2 x 10-5 O-cm 2. We observed a continuous silicon-oxide layer in the thinner contact structures, which failed after 36 h of heating. It was found that the interface between TaSix and NiySi was weakened by the accumulation of free carbon (produced by the reaction of Ni and SiC), which in turn facilitated oxygen diffusion from the contact edges. Additional oxygen diffusion occurred along grain boundaries in the Pt overlayer. Meanwhile, thicker contacts, with less interfacial free carbon and enhanced electrical stability contained a much lower oxygen concentration that was distributed across the contact layers, precluding the formation of an electrically insulating contact structure.

  3. Observer-Based Perturbation Extremum Seeking Control with Input Constraints for Direct-Contact Membrane Distillation Process

    KAUST Repository

    Eleiwi, Fadi

    2017-05-08

    An Observer-based Perturbation Extremum Seeking Control (PESC) is proposed for a Direct-Contact Membrane Distillation (DCMD) process. The process is described with a dynamic model that is based on a 2D Advection-Diffusion Equation (ADE) model which has pump flow rates as process inputs. The objective of the controller is to optimize the trade-off between the permeate mass flux and the energy consumption by the pumps inside the process. Cases of single and multiple control inputs are considered through the use of only the feed pump flow rate or both the feed and the permeate pump flow rates. A nonlinear Lyapunov-based observer is designed to provide an estimation for the temperature distribution all over the designated domain of the DCMD process. Moreover, control inputs are constrained with an anti-windup technique to be within feasible and physical ranges. Performance of the proposed structure is analyzed, and simulations based on real DCMD process parameters for each control input are provided.

  4. The epidemiology of medical emergency contacts outside hospitals in Norway - a prospective population based study

    Directory of Open Access Journals (Sweden)

    Burman Robert

    2010-02-01

    Full Text Available Abstract Introduction There is a lack of epidemiological knowledge on medical emergencies outside hospitals in Norway. The aim of the present study was to obtain representative data on the epidemiology of medical emergencies classified as "red responses" in Norway. Method Three emergency medical dispatch centres (EMCCs were chosen as catchment areas, covering 816 000 inhabitants. During a three month period in 2007 the EMCCs gathered information on every situation that was triaged as a red response, according to The Norwegian Index of Medical Emergencies (Index. Records from ground ambulances, air ambulances, and the primary care doctors were subsequently collected. International Classification of Primary Care - 2 symptom codes (ICPC-2 and The National Committee on Aeronautics (NACA Score System were given retrospectively. Results Total incidence of red response situations was 5 105 during the three month period. 394 patients were involved in 138 accidents, and 181 situations were without patients, resulting in a total of 5 180 patients. The patients' age ranged from 0 to 107 years, with a median age of 57, and 55% were male. 90% of the red responses were medical problems with a large variation of symptoms, the remainder being accidents. 70% of the patients were in a non-life-threatening situation. Within the accident group, males accounted for 61%, and 35% were aged between 10 and 29 years, with a median age of 37 years. Few of the 39 chapters in the Index were used, A10 "Chest pain" was the most common one (22% of all situations. ICPC-2 symptom codes showed that cardiovascular, syncope/coma, respiratory and neurological problems were most common. 50% of all patients in a sever situation (NACA score 4-7 were > 70 years of age. Conclusions The results show that emergency medicine based on 816 000 Norwegians mainly consists of medical problems, where the majority of the patients have a non-life-threatening situation. More focus on the emergency

  5. A Vision-Based Approach for Estimating Contact Forces: Applications to Robot-Assisted Surgery

    Directory of Open Access Journals (Sweden)

    C. W. Kennedy

    2005-01-01

    Full Text Available The primary goal of this paper is to provide force feedback to the user using vision-based techniques. The approach presented in this paper can be used to provide force feedback to the surgeon for robot-assisted procedures. As proof of concept, we have developed a linear elastic finite element model (FEM of a rubber membrane whereby the nodal displacements of the membrane points are measured using vision. These nodal displacements are the input into our finite element model. In the first experiment, we track the deformation of the membrane in real-time through stereovision and compare it with the actual deformation computed through forward kinematics of the robot arm. On the basis of accurate deformation estimation through vision, we test the physical model of a membrane developed through finite element techniques. The FEM model accurately reflects the interaction forces on the user console when the interaction forces of the robot arm with the membrane are compared with those experienced by the surgeon on the console through the force feedback device. In the second experiment, the PHANToM haptic interface device is used to control the Mitsubishi PA-10 robot arm and interact with the membrane in real-time. Image data obtained through vision of the deformation of the membrane is used as the displacement input for the FEM model to compute the local interaction forces which are then displayed on the user console for providing force feedback and hence closing the loop.

  6. The hybrid energy storages based on batteries and ultracapacitors for contact microwelding

    Directory of Open Access Journals (Sweden)

    Bondarenko Yu. V.

    2014-08-01

    Full Text Available Micro resistance welding is an effective way to reliably join small-scale parts. It is widely used in electronics and instrument-making. The important particularities of micro resistance welding are pulse character of energy consumption, non-linear load and special form of current pulses. So, these particularities of welding process cause negative influence on the mains. One of the known ways to avoid it is to use autonomous power supplies for micro resistance welding machines. The important task for building autonomous power supplies is to choose effective energy storages, which have high capacity and small internal resistance, and which are capable to be charged and deliver energy to load very quickly. The solution of this task is seen in using hybrid energy storages, which include accumulators and ultracapacitors. The accumulators are able to provide high energy capacitance and the ultracapacitors are able to provide fast energy delivery. The possibility of application of hybrid energy storages, based on accumulator batteries and ultracapacitors, in micro resistance welding machines is confirmed with computer simulation. Two variants of hybrid energy storages are proposed. These hybrid energy storages have high power and dynamic characteristics, which are sufficient to generate current pulses for welding according to necessary settings.

  7. Experimental and Quasi-Experimental Studies of Inquiry-Based Science Teaching: A Meta-Analysis

    Science.gov (United States)

    Furtak, Erin Marie; Seidel, Tina; Iverson, Heidi; Briggs, Derek C.

    2012-01-01

    Although previous meta-analyses have indicated a connection between inquiry-based teaching and improved student learning, the type of instruction characterized as inquiry based has varied greatly, and few have focused on the extent to which activities are led by the teacher or student. This meta-analysis introduces a framework for inquiry-based…

  8. Late and very-late first-contact schizophrenia and the risk of dementia--a nationwide register based study

    DEFF Research Database (Denmark)

    Kørner, Alex; Lopez, Ana Garcia; Lauritzen, Lise

    2009-01-01

    OBJECTIVE: To examine whether late and very-late first-contact schizophrenia carry a risk for later development of dementia. METHODS: By linkage of the psychiatric and the somatic nation-wide registers of all out- and in-patients with hospital contact in Denmark, we identified all patients...... with first ever contact during the period from January 1994 to December 2001 with one of the index main diagnoses: late (age >or=40) and very-late first-contact (age >or=60) schizophrenia. First contact osteoarthritis patients as well as data on the general population were used as controls. The first...... diagnosis of dementia for each individual at discharge or at out-patient contact was established. The probability of getting a dementia diagnosis is estimated using Poisson regression models with dementia as the outcome of interest. RESULTS: Twelve thousand six hundred and sixteen and 7,712 individuals were...

  9. Testability of evolutionary game dynamics based on experimental economics data

    Science.gov (United States)

    Wang, Yijia; Chen, Xiaojie; Wang, Zhijian

    2017-11-01

    Understanding the dynamic processes of a real game system requires an appropriate dynamics model, and rigorously testing a dynamics model is nontrivial. In our methodological research, we develop an approach to testing the validity of game dynamics models that considers the dynamic patterns of angular momentum and speed as measurement variables. Using Rock-Paper-Scissors (RPS) games as an example, we illustrate the geometric patterns in the experiment data. We then derive the related theoretical patterns from a series of typical dynamics models. By testing the goodness-of-fit between the experimental and theoretical patterns, we show that the validity of these models can be evaluated quantitatively. Our approach establishes a link between dynamics models and experimental systems, which is, to the best of our knowledge, the most effective and rigorous strategy for ascertaining the testability of evolutionary game dynamics models.

  10. Competitive sports participation in high school and subsequent substance use in young adulthood: Assessing differences based on level of contact.

    Science.gov (United States)

    Veliz, Philip; Schulenberg, John; Patrick, Megan; Kloska, Deb; McCabe, Sean Esteban; Zarrett, Nicole

    2017-03-01

    The objective of this analysis is to examine how participation in different types of competitive sports (based on level of contact) during high school is associated with substance use 1 to 4 years after the 12(th) grade. The analysis uses nationally representative samples of 12(th) graders from the Monitoring the Future Study who were followed 1 to 4 years after the 12(th) grade. The longitudinal sample consisted of 970 12(th) graders from six recent cohorts (2006-2011). The analyses found that respondents who participated in at least one competitive sport during the 12(th) grade had greater odds of binge drinking during the past two weeks (AOR = 2.04; 95% CI = 1.43, 2.90) 1 to 4 years after the 12(th) grade, when compared to their peers who did not participate in sports during their 12(th) grade year. Moreover, respondents who participated in high-contact sports (i.e., football, ice hockey, lacrosse, and wrestling) had greater odds of binge drinking (AOR = 1.80; 95% CI = 1.18, 2.72) and engaging in marijuana use during the past 30 days (AOR = 1.81; 95% CI = 1.12, 2.93) 1 to 4 years after the 12(th) grade when compared to their peers who did not participate in these types of sports during their 12(th) grade year. Accordingly, the findings indicate important distinctions in sport participation experiences on long-term substance use risk that can help inform potential interventions among young athletes.

  11. Wearable Sweatband Sensor Platform Based on Gold Nanodendrite Array as Efficient Solid Contact of Ion-Selective Electrode.

    Science.gov (United States)

    Wang, Shuqi; Wu, Yongjin; Gu, Yang; Li, Tie; Luo, Hui; Li, Lian-Hui; Bai, Yuanyuan; Li, Lili; Liu, Lin; Cao, Yudong; Ding, Haiyan; Zhang, Ting

    2017-10-03

    As chemical sensors are in great demand for portable and wearable analytical applications, it is highly desirable to develop an all-solid-state ion-selective electrode (ISE) and reference electrode (RE) platform with simplicity and stability. Here we propose a wearable sensor platform with a new type of all-solid-state ISE based on a gold nanodendrite (AuND) array electrode as the solid contact and a poly(vinyl acetate)/inorganic salt (PVA/KCl) membrane-coated all-solid-state RE. A simple and controllable method was developed to fabricate the AuNDs on a microwell array patterned chip by one-step electrodeposition without additional processing. For the first time, the AuND electrodes with different real surface area and double layer capacitance were developed as solid contact of the Na+-ISE to investigate the relationship between performance of the ISE and surface area. As-prepared AuND-ISE with larger surface area (∼7.23 cm2) exhibited enhanced potential stability compared to those with smaller surface area (∼1.85 cm2) and to bare Au ISE. Important as the ISE, the PVA/KCl membrane-coated Ag/AgCl RE exhibited highly stable potential even after 3 months' storage. Finally, a wearable sweatband sensor platform was developed for efficient sweat collection and real-time analysis of sweat sodium during indoor exercise. This all-solid-state ISE and RE integrated sensor platform provided a very simple and reliable way to construct diverse portable and wearable devices for healthcare, sports, clinical diagnosis, and environmental analysis applications.

  12. Model-Based Optimal Experimental Design for Complex Physical Systems

    Science.gov (United States)

    2015-12-03

    optimality aspect of sOED, another major difficulty remains: to numer - ically represent non-Gaussian, continuous random variable posteriors (i.e...construct, as they involve solving a convex optimization problem that can be easily separated into independent sub-problems for each dimension, and requires...OM Knio. “Bayesian Guided Optimal Experimental Design for Reactive Multilayers.” In preparation, 2015. 6. X Huan, “ Numerical Approaches for Sequential

  13. Cellular bases of experimental amebic liver abscess formation.

    Science.gov (United States)

    Tsutsumi, V.; Mena-Lopez, R.; Anaya-Velazquez, F.; Martinez-Palomo, A.

    1984-01-01

    The complete sequence of morphologic events during amebic liver abscess formation in the hamster has been studied, from the lodgement of amebas in the hepatic sinusoids to the development of extensive liver necrosis. Following intraportal inoculation of live amebas, the early stages of the lesion (from 1 to 12 hours) were characterized by acute cellular infiltration composed of an increasingly large number of polymorphonuclear leukocytes, which surrounded centrally located trophozoites. Histiocytes and lysed leukocytes were situated on the periphery of the lesions. Hepatocytes close to the early lesions showed degenerative changes which led to necrosis; however, direct contact of liver cells with amebas was very rarely observed. At later stages, the extent of necrosis increased, macrophages and epithelioid cells replaced most leukocytes, and well-organized granulomas developed. Extensive necrosis associated with fused granulomas was present by Day 7. The results suggest that Entamoeba histolytica trophozoites do not produce amebic liver abscesses in hamsters through direct lysis of hepatocytes. Rather, tissue destruction is the result of the accumulation and subsequent lysis of leukocytes and macrophages surrounding the amebas. Images Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Figure 6 PMID:6385728

  14. A 3D contact analysis approach for the visualization of the electrical contact asperities

    OpenAIRE

    Constantinos C. Roussos; Jonathan Swingler

    2017-01-01

    The electrical contact is an important phenomenon that should be given into consideration to achieve better performance and long term reliability for the design of devices. Based upon this importance, the electrical contact interface has been visualized as a ??3D Contact Map?? and used in order to investigate the contact asperities. The contact asperities describe the structures above and below the contact spots (the contact spots define the 3D contact map) to the two conductors which make th...

  15. Fractal Geometry-Based Hypergeometric Time Series Solution to the Hereditary Thermal Creep Model for the Contact of Rough Surfaces Using the Kelvin-Voigt Medium

    Directory of Open Access Journals (Sweden)

    Osama M. Abuzeid

    2010-01-01

    Full Text Available This paper aims at constructing a continuous hereditary creep model for the thermoviscoelastic contact of a rough punch and a smooth surface of a rigid half-space. The used model considers the rough surface as a function of the applied load and temperatures. The material of the rough punch surface is assumed to behave as Kelvin-Voigt viscoelastic material. Such a model uses elastic springs and viscous dashpots in parallel. The fractal-based punch surface is modelled using a deterministic Cantor structure. An asymptotic power law, deduced using approximate iterative relations, is used to express the punch surface creep which is a time-dependent inelastic deformation. The suggested law utilized the hypergeometric time series to relate the variables of creep as a function of remote forces, body temperatures, and time. The model is valid when the approach of punch surface and half space is in the order of the size of the surface roughness. The closed-form results are obtained for selected values of the system parameters; the fractal surface roughness and various material properties. The obtained results show good agreement with published experimental results, and the methodology can be further extended to other structures such as the Kelvin-Voigt medium within electronic circuits and systems.

  16. Demarcation line depth after contact lens-assisted corneal crosslinking for progressive keratoconus: Comparison of dextran-based and hydroxypropyl methylcellulose-based riboflavin solutions.

    Science.gov (United States)

    Malhotra, Chintan; Jain, Arun K; Gupta, Amit; Ram, Jagat; Ramatchandirane, Balamurugan; Dhingra, Deepika; Sachdeva, Kulbhushan; Kumar, Amit

    2017-10-01

    To compare the demarcation line depth after contact lens-assisted corneal crosslinking (CXL) for progressive keratoconus using dextran-based and hydroxypropyl methylcellulose (HPMC)-based riboflavin solutions. Advanced Eye Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, India. Retrospective case series. Patients with preoperative epithelium-on (epi-on) minimum corneal thickness between 350 μm and 450 μm having contact lens-assisted CXL for progressive keratoconus were crosslinked with isoosmolar 0.1% riboflavin in 20% dextran 500 or HPMC 1.1%. The primary outcome measure was the mean demarcation line depth measured 1 month postoperatively on anterior-segment optical coherence tomography. The secondary outcome measure was change in endothelial cell density (ECD) 6 months from baseline. The study comprised 21 patients (21 eyes, 9 in the HPMC group and 12 in the dextran group). The mean demarcation line depth was deeper in the HPMC group (308.22 μm ± 84.19 [SD]) than in the dextran group (235.33 ± 64.87 μm) (P < .04). This difference remained significant (P = .02) even after controlling for the preoperative lesser epi-on minimum corneal thickness in the HPMC group (385.56 ±13.81 μm) versus the dextran group (413.08 ± 29.58 μm) (P < .02). The ECD 6 months after contact lens-assisted CXL was comparable to the baseline levels in both groups (P = .19 and P = .09, respectively). During contact lens-assisted CXL, HPMC-based riboflavin seemed to be associated with a deeper demarcation line than dextran-based riboflavin, although both solutions were safe for the endothelium at 6 months. Copyright © 2017 ASCRS and ESCRS. Published by Elsevier Inc. All rights reserved.

  17. Classification of hand eczema: clinical and aetiological types. Based on the guideline of the Danish Contact Dermatitis Group

    DEFF Research Database (Denmark)

    Johansen, Jeanne Duus; Hald, Marianne; Andersen, Bo Lasthein

    2011-01-01

    aetiological diagnosis. Results. Irritant contact dermatitis was most frequent in chronic, dry fissured hand eczema (44.3%), pulpitis (41.7%), and nummular hand eczema (40.9%), whereas allergic contact dermatitis dominated in vesicular types of hand eczema, with recurrent (35%) and few (24.2%) eruptions...

  18. Observer Based Sliding Mode Attitude Control: Theoretical and Experimental Results

    Directory of Open Access Journals (Sweden)

    U. Jørgensen

    2011-07-01

    Full Text Available In this paper we present the design of a sliding mode controller for attitude control of spacecraft actuated by three orthogonal reaction wheels. The equilibrium of the closed loop system is proved to be asymptotically stable in the sense of Lyapunov. Due to cases where spacecraft do not have angular velocity measurements, an estimator for the generalized velocity is derived and asymptotic stability is proven for the observer. The approach is tested on an experimental platform with a sphere shaped Autonomous Underwater Vehicle SATellite: AUVSAT, developed at the Norwegian University of Science and Technology.

  19. Ionic liquids based on phosphonium cations as neat lubricants or lubricant additives for a steel/steel contact.

    Science.gov (United States)

    Otero, Inés; López, Enriqueta R; Reichelt, Manuela; Villanueva, María; Salgado, Josefa; Fernández, Josefa

    2014-08-13

    After doing several miscibility essays with eight ionic liquids (ILs) and four base oils, the ILs tri(butyl)ethylphosphonium diethylphosphate [P4,4,4,2][C2C2PO4] and trihexyl(tetradecyl)phosphonium tris(pentafluoroethyl)trifluorophosphate [P6,6,6,14][(C2F5)3PF3] were selected to be studied as lubricant additives. The neat IL [P4,4,4,2][C2C2PO4], the base oils, and several blends were characterized in terms of density, viscosity, and thermal stability. The tribological performance of the miscible base oil/IL blends (1 wt %) and the neat [P4,4,4,2][C2C2PO4] were evaluated for the lubrication of an AISI 420 steel-100Cr6 steel contact pair. The friction coefficients and wear volumes obtained are also compared with those corresponding to the pure base oils and their mixtures with conventional additive zinc dialkyldithiophosphate (ZDDP). As neat lubricants, [P4,4,4,2][C2C2PO4] showed the best antifriction ability, whereas in terms of wear, better results were obtained with [P6,6,6,14][(C2F5)3PF3]. However, higher improvements in both friction and wear were found for blends containing [P4,4,4,2][C2C2PO4]. XPS analyses of the worn surfaces lubricated with these mixtures indicated the presence of phosphorus in the tribofilm formed on the wear track. However, this compound was slightly detected on tribosamples lubricated with blends containing [P6,6,6,14][(C2F5)3PF3].

  20. Characteristics of corneal biomechanical responses detected by a non-contact scheimpflug-based tonometer in eyes with glaucoma.

    Science.gov (United States)

    Jung, Younhea; Park, Hae-Young L; Yang, Hee Jung; Park, Chan Kee

    2017-06-21

    To determine the corneal biomechanical properties in eyes with glaucoma using a non-contact Scheimpflug-based tonometer. Corneal biomechanical responses were examined using a non-contact Scheimpflug-based tonometer. The tonometer parameters of the normal control group (n = 75) were compared with those of the glaucoma group (n = 136), including an analysis of glaucoma subgroups categorized by visual field loss. After adjusting for potential confounding factors, including the intraocular pressure (IOP), central corneal thickness (CCT), age and axial length, the deformation amplitude was smaller in the glaucoma group (1.09 ± 0.02 mm) than in the normal control group (1.12 ± 0.02 mm; p value = 0.031). The deformation amplitude and the deflection amplitude of the severe glaucoma group (1.12 ± 0.02 mm and 0.92 ± 0.01 mm) were significantly greater than that of the early glaucoma group (1.07 ± 0.01( ) mm and 0.88 ± 0.11 mm, p = 0.006 and p = 0.031), whereas that of the moderate glaucoma group (1.09 ± 0.02 mm and 0.90 ± 0.02 mm) was greater than that of the early glaucoma group, but this difference was not statistically significant. The deformation amplitude showed a negative correlation with the CCT in the normal control group (r = -0.235), with a weaker negative relationship observed in the early glaucoma group (r = -0.099). However, in the moderate and severe glaucoma groups, the deformation amplitude showed a positive relationship with the CCT, showing an inverse relationship. The duration and number of antiglaucomatous eyedrops used had negative correlations with the CCT in eyes with moderate and severe glaucoma. Overall, the glaucoma group showed significantly less deformable corneas than did the normal controls, even after adjusting for the IOP, CCT, age and axial length. However, there were also differences according to the severity of glaucoma, where the corneal deformation amplitude was greater in the severe glaucoma

  1. Web-based treatment program using intensive therapeutic contact for patients with eating disorders: before-after study.

    Science.gov (United States)

    ter Huurne, Elke D; Postel, Marloes G; de Haan, Hein A; Drossaert, Constance H C; DeJong, Cor A J

    2013-02-04

    Although eating disorders are common in the Netherlands, only a few patients are treated by mental health care professionals. To reach and treat more patients with eating disorders, Tactus Addiction Treatment developed a web-based treatment program with asynchronous and intensive personalized communication between the patient and the therapist. This pilot study evaluated the web-based treatment program using intensive therapeutic contact in a population of 165 patients with an eating disorder. In a pre-post design with 6-week and 6-month follow-ups, eating disorder psychopathology, body dissatisfaction, Body Mass Index, physical and mental health, and quality of life were measured. The participant's satisfaction with the web-based treatment program was also studied. Attrition data were collected, and participants were classified as noncompleters if they did not complete all 10 assignments of the web-based treatment program. Differences in baseline characteristics between completers and noncompleters were studied, as well as reasons for noncompletion. Furthermore, differences in treatment effectiveness, treatment adherence, and baseline characteristics between participants of the three major eating disorder diagnostic groups EDNOS (n=115), BN purging (n=24), and BN nonpurging (n=24) were measured. Of the 165 participants who started the web-based treatment program, 89 participants (54%) completed all of the program assignments (completers) and 76 participants (46%) ended the program prematurely (noncompleters). Severe body dissatisfaction and physical and mental health problems seemed to have a negative impact on the completion of the web-based treatment program. Among the participants who completed the treatment program, significant improvements were found in eating disorder psychopathology (F=54.6, df = 68, Pmental health also significantly improved, and almost all of these positive effects were sustained up to 6 months after the participants had completed the web-based

  2. Experimental and trial-based study of Resilient Packet Ring

    Science.gov (United States)

    Ramnath, Vasudha; Cheng, Heng Seng; Ngoh, Lek Heng

    2002-08-01

    An experimental study of the Resilient Packet Ring (RPR) media access control (MAC) technology that is optimized for IP traffic in the metropolitan-area-network (MAN) environment is described. The study involved the deployment and trials of a RPR testbed encompassing a public optical fiber infrastructure in which Cisco Systems' Dynamic Packet Transport (DPT) Ring Technology - a prestandard RPR implementation - was used. We focus on a number of important RPR protocol features that are vital to the future success of RPR as a MAN/wide-area-network (WAN) network technology. Related research on RPR/DPT has been done so far through simulation studies only. Standardization of RPR is currently being performed by the Institute of Electrical and Electronics Engineers (IEEE) 802.17 working group and is expected to be completed in 2003. Also, we present and discuss the experiments and tests performed to investigate the key features of RPR, along with the results obtained.

  3. Experimental demonstration of a magnetically tunable ferrite based metamaterial absorber.

    Science.gov (United States)

    Huang, Yongjun; Wen, Guangjun; Zhu, Weiren; Li, Jian; Si, Li-Ming; Premaratne, Malin

    2014-06-30

    We synthesize and systematically characterize a novel type of magnetically tunable metamaterial absorber (MA) by integrating ferrite as a substrate or superstrate into a conventional passive MA. The nearly perfect absorption and tunability of this device is studied both numerically and experimentally within X-band (8-12 GHz) in a rectangular waveguide setup. Our measurements clearly show that the resonant frequency of the MA can be shifted across a wide frequency band by continuous adjustment of a magnetic field acting on the ferrite. Moreover, the effects of substrate/superstrate's thickness on the MA's tunability are discussed. The insight gained from the generic analysis enabled us to design an optimized tunable MA with relative frequency tuning range as larger as 11.5% while keeping the absorptivity higher than 98.5%. Our results pave a path towards applications with tunable devices, such as selective thermal emitters, sensors, and bolometers.

  4. Spectroscopic On-Line Monitoring of Cu/W Contacts Erosion in HVCBs Using Optical-Fibre Based Sensor and Chromatic Methodology

    Directory of Open Access Journals (Sweden)

    Zhixiang Wang

    2017-03-01

    Full Text Available Contact erosion is one of the most crucial factors affecting the electrical service lifetime of high-voltage circuit breakers (HVCBs. On-line monitoring the contacts’ erosion degree is increasingly in demand for the sake of condition based maintenance to guarantee the functional operation of HVCBs. A spectroscopic monitoring system has been designed based upon a commercial 245 kV/40 kA S F 6 live tank circuit breaker with copper–tungsten (28 wt % and 72 wt % arcing contacts at atmospheric S F 6 pressure. Three optical-fibre based sensors are used to capture the time-resolved spectra of arcs. A novel approach using chromatic methods to process the time-resolved spectral signal has been proposed. The processed chromatic parameters have been interpreted to show that the time variation of spectral emission from the contact material and quenching gas are closely correlated to the mass loss and surface degradation of the plug arcing contact. The feasibility of applying this method to online monitoring of contact erosion is indicated.

  5. Physical-mechanical image of the cell surface on the base of AFM data in contact mode

    Science.gov (United States)

    Starodubtseva, M. N.; Starodubtsev, I. E.; Yegorenkov, N. I.; Kuzhel, N. S.; Konstantinova, E. E.; Chizhik, S. A.

    2017-10-01

    Physical and mechanical properties of the cell surface are well-known markers of a cell state. The complex of the parameters characterizing the cell surface properties, such as the elastic modulus (E), the parameters of adhesive (Fa), and friction (Ff) forces can be measured using atomic force microscope (AFM) in a contact mode and form namely the physical-mechanical image of the cell surface that is a fundamental element of the cell mechanical phenotype. The paper aims at forming the physical-mechanical images of the surface of two types of glutaraldehyde-fixed cancerous cells (human epithelial cells of larynx carcinoma, HEp-2c cells, and breast adenocarcinoma, MCF-7 cells) based on the data obtained by AFM in air and revealing the basic difference between them. The average values of friction, elastic and adhesive forces, and the roughness of lateral force maps, as well as dependence of the fractal dimension of lateral force maps on Z-scale factor have been studied. We have revealed that the response of microscale areas of the HEp-2c cell surface having numerous microvilli to external mechanical forces is less expressed and more homogeneous in comparison with the response of MCF-7 cell surface.

  6. Experimental investigations of sensor-based surface following tasks by a mobile manipulator

    Energy Technology Data Exchange (ETDEWEB)

    Reister, D.B.; Unseren, M.A.; Baker, J.E.; Pin, F.G.

    1993-10-01

    This paper discusses experimental investigations of the feasibility and requirements of simultaneous external-sensor-based-control of the wheeled platform and the manipulator of a mobile robot. The experiments involve 3-D arbitrary surface following by the manipulator while the platform moves along a predefined trajectory. A variety of concave and convex surfaces were used in the experiments, during which target and measured values of the platform and arm positions and orientations, together with the surface absolute location and normal estimates, were logged at 10 Hz. For all experiments, the data logs showed significant noise, at high frequency, in the calculated surface normal values despite smooth tracking of their target values by the arm and the platform, with typical closed loop delays between target and achieved values of the order of 100 msec. This high-frequency noise in the calculated values is conjectured to result mainly from the arm`s transmission cables compliance and backlash in the spherical wrist gears. On the other hand, the end-effector distance to the surface showed some low frequency errors of the order of {plus_minus}20%The two major sources of these low frequency errors appeared to reside respectively in the low values of the velocity bound and gain parameters utilized to filter the high frequency noise in the calculated normal values prior to using them as input to the arm control, and in the rolling contact of the platform`s rubber-coated wheels on the ground where significant errors in the platform`s positions and orientations can accumulate.

  7. Reducing contact resistance in graphene devices through contact area patterning.

    Science.gov (United States)

    Smith, Joshua T; Franklin, Aaron D; Farmer, Damon B; Dimitrakopoulos, Christos D

    2013-04-23

    Performance of graphene electronics is limited by contact resistance associated with the metal-graphene (M-G) interface, where unique transport challenges arise as carriers are injected from a 3D metal into a 2D-graphene sheet. In this work, enhanced carrier injection is experimentally achieved in graphene devices by forming cuts in the graphene within the contact regions. These cuts are oriented normal to the channel and facilitate bonding between the contact metal and carbon atoms at the graphene cut edges, reproducibly maximizing "edge-contacted" injection. Despite the reduction in M-G contact area caused by these cuts, we find that a 32% reduction in contact resistance results in Cu-contacted, two-terminal devices, while a 22% reduction is achieved for top-gated graphene transistors with Pd contacts as compared to conventionally fabricated devices. The crucial role of contact annealing to facilitate this improvement is also elucidated. This simple approach provides a reliable and reproducible means of lowering contact resistance in graphene devices to bolster performance. Importantly, this enhancement requires no additional processing steps.

  8. A CWT-based methodology for piston slap experimental characterization

    Science.gov (United States)

    Buzzoni, M.; Mucchi, E.; Dalpiaz, G.

    2017-03-01

    Noise and vibration control in mechanical systems has become ever more significant for automotive industry where the comfort of the passenger compartment represents a challenging issue for car manufacturers. The reduction of piston slap noise is pivotal for a good design of IC engines. In this scenario, a methodology has been developed for the vibro-acoustic assessment of IC diesel engines by means of design changes in piston to cylinder bore clearance. Vibration signals have been analysed by means of advanced signal processing techniques taking advantage of cyclostationarity theory. The procedure departs from the analysis of the Continuous Wavelet Transform (CWT) in order to identify a representative frequency band of piston slap phenomenon. Such a frequency band has been exploited as the input data in the further signal processing analysis that involves the envelope analysis of the second order cyclostationary component of the signal. The second order harmonic component has been used as the benchmark parameter of piston slap noise. An experimental procedure of vibrational benchmarking is proposed and verified at different operational conditions in real IC engines actually equipped on cars. This study clearly underlines the crucial role of the transducer positioning when differences among real piston-to-cylinder clearances are considered. In particular, the proposed methodology is effective for the sensors placed on the outer cylinder wall in all the tested conditions.

  9. kente simulation painting: an experimental style based on the ...

    African Journals Online (AJOL)

    2006-12-03

    Dec 3, 2006 ... MATERIALS AND METHODS. The usual materials required in making drawings and paintings, such as a pencil, brush, paper or canvas, and colour medium be it water based, oil or acrylic are suitable for the kente painting technique. Four steps or production processes are involved in this style of painting.

  10. Cu(In,Ga)Se2Solar Cells with Amorphous In2O3-Based Front Contact Layers.

    Science.gov (United States)

    Koida, Takashi; Ueno, Yuko; Nishinaga, Jiro; Higuchi, Hirohumi; Takahashi, Hideki; Iioka, Masayuki; Shibata, Hajime; Niki, Shigeru

    2017-09-06

    Amorphous (a-) In 2 O 3 -based front contact layers composed of transparent conducting oxide (TCO) and transparent oxide semiconductor (TOS) layers were proved to be effective in enhancing the short-circuit current density (J sc ) of Cu(In,Ga)Se 2 (CIGS) solar cells with a glass/Mo/CIGS/CdS/TOS/TCO structure, while maintaining high fill factor (FF) and open-circuit voltage (V oc ). An n-type a-In-Ga-Zn-O layer was introduced between the CdS and TCO layers. Unlike unintentionally doped ZnO broadly used as TOS layers in CIGS solar cells, the grain-boundary(GB)-free amorphous structure of the a-In-Ga-Zn-O layers allowed high electron mobility with superior control over the carrier density (N). High FF and V oc values were achieved in solar cells containing a-In-Ga-Zn-O layers with N values broadly ranging from 2 × 10 15 to 3 × 10 18 cm -3 . The decrease in FF and V oc produced by the electronic inhomogeneity of solar cells was mitigated by controlling the series resistance within the TOS layer of CIGS solar cells. In addition, a-In 2 O 3 :H and a-In-Zn-O layers exhibited higher electron mobilities than the ZnO:Al layers conventionally used as TCO layers in CIGS solar cells. The In 2 O 3 -based layers exhibited lower free carrier absorption while maintaining similar sheet resistance than ZnO:Al. The TCO and TOS materials and their combinations did not significantly change the V oc of the CIGS solar cells and the mini-modules.

  11. Experimental method to predict avalanches based on neural networks

    Directory of Open Access Journals (Sweden)

    V. V. Zhdanov

    2016-01-01

    Full Text Available The article presents results of experimental use of currently available statistical methods to classify the avalanche‑dangerous precipitations and snowfalls in the Kishi Almaty river basin. The avalanche service of Kazakhstan uses graphical methods for prediction of avalanches developed by I.V. Kondrashov and E.I. Kolesnikov. The main objective of this work was to develop a modern model that could be used directly at the avalanche stations. Classification of winter precipitations into dangerous snowfalls and non‑dangerous ones was performed by two following ways: the linear discriminant function (canonical analysis and artificial neural networks. Observational data on weather and avalanches in the gorge Kishi Almaty in the gorge Kishi Almaty were used as a training sample. Coefficients for the canonical variables were calculated by the software «Statistica» (Russian version 6.0, and then the necessary formula had been constructed. The accuracy of the above classification was 96%. Simulator by the authors L.N. Yasnitsky and F.М. Cherepanov was used to learn the neural networks. The trained neural network demonstrated 98% accuracy of the classification. Prepared statistical models are recommended to be tested at the snow‑avalanche stations. Results of the tests will be used for estimation of the model quality and its readiness for the operational work. In future, we plan to apply these models for classification of the avalanche danger by the five‑point international scale.

  12. Experimental investigations and simplified seismic analysis of the structural system JUBHome BASE

    OpenAIRE

    Stermecki, Marko

    2015-01-01

    The experimental investigations of the structural system JUBHome BASE are presented in the first part of the thesis. JUBHome BASE is a foundation assembly which consists of hydro isolation, thermal isolation (EPS) and reinforced concrete foundation slab. The main objective of the experimental investigations, which were performed at the Faculty of Civil and Geodetic Engineering, was to determine the shear resistance of the JUBHome BASE system and the shear resistance of the cont...

  13. Numerical simulation and experimental validation of inverted planar perovskite solar cells based on NiOx hole transport layer

    Science.gov (United States)

    Wei, Xiaoqing; Wang, Xian; Jiang, Hailong; Huang, Yongliang; Han, Anjun; Gao, Qi; Bian, Jiantao; Liu, Zhengxin

    2017-12-01

    Numerical simulation of inverted planar perovskite solar cells based on NiOx hole transport layer was performed with AMPS-1D program. The simulated device parameters were shown to agree well with our experimental work. The simulated results revealed that the device contained typical p-i-n junction configuration. The optimum thickness of the absorber, the effects of the absorber quality, the defect density of interfaces, the effects of VBO and CBO, the interface contact at front and back electrodes were analyzed. Open-circuit voltage mainly depended on the defect density in CH3NH3PbI3 layer, the recombination at HTL/CH3NH3PbI3 and ETL/CH3NH3PbI3 interface, the values of VBO and CBO, while short-circuit current mainly depended on the thickness of CH3NH3PbI3 layer. Fill factor was significantly influenced by the interface contact at front and back electrodes. Remarkably, a power conversion efficiency of 21.8% is obtained under optimised conditions. Real devices with PCE of up to 15% were obtained by initially optimizing the preparation of CH3NH3PbI3 absorber layer. Our work can provide some important guidance for device design and optimization from the considerations of both theory and experiment.

  14. BASES MOLECULARES DE LA INMUNOTOXICOLOGÍA EXPERIMENTAL DE LA MARIHUANA Molecular bases of experimental immunotoxicology of marijuana

    Directory of Open Access Journals (Sweden)

    Guillermo Orlando Narváez Quintero

    2006-10-01

    Full Text Available La marihuana es una de las drogas de abuso más antiguas conocidas por la humanidad. Sin embargo, sólo recientemente se han comenzado a comprender los mecanismos bioquímicos que están detrás de los efectos toxicos de la droga en el sistema inmune. Los modelos experimentales in vitro e in vivo , tanto en animales como en humanos, muestran un claro patrón de alteración inmunológica, apuntando hacia la supresión de la respesta inmune de tipo celular Th1-dependiente. En estos eventos la participación de los receptores para canabinoi­des expresados en la superficie de los inmunocitos es muy importante.Marijuana is one of the oldest drugs known by humankind; however, only recently the biochemical mechanism behind the toxicodi­namics effects have begun becoming clear. The experimental models, in vitro and in vivo, both in animals and humans, show a clear tendency of immune alteration, pointing out suppression of the Th1-dependent immune response. In these events the involvement of cannabinoid receptors on the surface of immunocites are remarkable.

  15. Experimental Verification of the Strain Non-Uniformity Index (SNI) based Failure Prediction

    Science.gov (United States)

    Dhumal, D. A.; Kulkarni, Pratik; Date, P. P.; Nandedkar, V. M.

    2016-08-01

    Formability of the sheet metal depends upon the uniformity of strain distribution, which depends on material properties, tooling and process parameters. Nakazima Test was conducted to study the strain distribution and establish the forming limits of AA 6016. The experimental conditions were simulated using AUTOFORM 5.2 Plus software and the failure predicted using the SNI based methodology. The failure predictions were correlated with the state of the experimentally deformed Nakazima samples, and also with the FLD based forming limits. The failure prediction from the SNI based methodology was found to correlate well with the state of the experimental Nakazima sample.

  16. Lumping of degree-based mean-field and pair-approximation equations for multistate contact processes

    Science.gov (United States)

    Kyriakopoulos, Charalampos; Grossmann, Gerrit; Wolf, Verena; Bortolussi, Luca

    2018-01-01

    Contact processes form a large and highly interesting class of dynamic processes on networks, including epidemic and information-spreading networks. While devising stochastic models of such processes is relatively easy, analyzing them is very challenging from a computational point of view, particularly for large networks appearing in real applications. One strategy to reduce the complexity of their analysis is to rely on approximations, often in terms of a set of differential equations capturing the evolution of a random node, distinguishing nodes with different topological contexts (i.e., different degrees of different neighborhoods), such as degree-based mean-field (DBMF), approximate-master-equation (AME), or pair-approximation (PA) approaches. The number of differential equations so obtained is typically proportional to the maximum degree kmax of the network, which is much smaller than the size of the master equation of the underlying stochastic model, yet numerically solving these equations can still be problematic for large kmax. In this paper, we consider AME and PA, extended to cope with multiple local states, and we provide an aggregation procedure that clusters together nodes having similar degrees, treating those in the same cluster as indistinguishable, thus reducing the number of equations while preserving an accurate description of global observables of interest. We also provide an automatic way to build such equations and to identify a small number of degree clusters that give accurate results. The method is tested on several case studies, where it shows a high level of compression and a reduction of computational time of several orders of magnitude for large networks, with minimal loss in accuracy.

  17. Experimental characterization of semiconductor-based thermal neutron detectors

    Energy Technology Data Exchange (ETDEWEB)

    Bedogni, R., E-mail: roberto.bedogni@lnf.infn.it [IFNF—LNF, via E. Fermi n. 40, 00044 Frascati, Roma (Italy); Bortot, D.; Pola, A.; Introini, M.V.; Lorenzoli, M. [Politecnico di Milano, Dipartimento di Energia, via La Masa 34, 20156 Milano (Italy); INFN—Milano, Via Celoria 16, 20133 Milano (Italy); Gómez-Ros, J.M. [IFNF—LNF, via E. Fermi n. 40, 00044 Frascati, Roma (Italy); CIEMAT, Av. Complutense 40, 28040 Madrid (Spain); Sacco, D. [IFNF—LNF, via E. Fermi n. 40, 00044 Frascati, Roma (Italy); INAIL—DIT, Via di Fontana Candida 1, 00040 Monteporzio Catone (Italy); Esposito, A.; Gentile, A.; Buonomo, B. [IFNF—LNF, via E. Fermi n. 40, 00044 Frascati, Roma (Italy); Palomba, M.; Grossi, A. [ENEA Triga RC-1C.R. Casaccia, via Anguillarese 301, 00060 S. Maria di Galeria, Roma (Italy)

    2015-04-21

    In the framework of NESCOFI@BTF and NEURAPID projects, active thermal neutron detectors were manufactured by depositing appropriate thickness of {sup 6}LiF on commercially available windowless p–i–n diodes. Detectors with different radiator thickness, ranging from 5 to 62 μm, were manufactured by evaporation-based deposition technique and exposed to known values of thermal neutron fluence in two thermal neutron facilities exhibiting different irradiation geometries. The following properties of the detector response were investigated and presented in this work: thickness dependence, impact of parasitic effects (photons and epithermal neutrons), linearity, isotropy, and radiation damage following exposure to large fluence (in the order of 10{sup 12} cm{sup −2})

  18. Women's Perceptions of Participation in an Extended Contact Text Message-Based Weight Loss Intervention: An Explorative Study.

    Science.gov (United States)

    Job, Jennifer R; Spark, Lauren C; Fjeldsoe, Brianna S; Eakin, Elizabeth G; Reeves, Marina M

    2017-02-27

    Extending contact with participants after the end of an initial weight loss intervention has been shown to lead to maintained weight loss and related behavioral change. Mobile phone text messaging (short message service, SMS) offers a low-cost and efficacious method to deliver extended contact. In this rapidly developing area, formative work is required to understand user perspectives of text message technology. An extended contact intervention delivered by text messages following an initial telephone-delivered weight loss intervention in breast cancer survivors provided this opportunity. The aim of this study was to qualitatively explore women's perceptions of participation in an extended contact intervention using text messaging to support long-term weight loss, physical activity, and dietary behavioral change. Following the end of an initial 6-month randomized controlled trial of a telephone-delivered weight loss intervention (versus usual care), participants received a 6-month extended contact intervention via tailored text messages. Participant perceptions of the different types of text messages, the content, tailoring, timing, and frequency of the text messages, and the length of the intervention were assessed through semistructured interviews conducted after the extended contact intervention. The interviews were transcribed verbatim and analyzed with key themes identified. Participants (n=27) were a mean age of 56.0 years (SD 7.8) and mean body mass index of 30.4 kg/m2 (SD 4.2) and were at a mean of 16.1 months (SD 3.1) postdiagnosis at study baseline. Participants perceived the text messages to be useful behavioral prompts and felt the messages kept them accountable to their behavioral change goals. The individual tailoring of the text message content and schedules was a key to the acceptability of the messages; however, some women preferred the support and real-time discussion via telephone calls (during the initial intervention) compared with the text

  19. Toward robust and accurate contact solvers for large deformation applications: a remapping/adaptivity framework for mortar-based methods

    Science.gov (United States)

    Kindo, Temesgen M.; Laursen, Tod A.; Dolbow, John E.

    2014-07-01

    In recent years, the mortar method has proven to be an effective spatial discretization strategy for large deformation contact problems, particularly when such problems feature deformable-to-deformable contact. The mortar approach has been shown to greatly enhance both the spatial accuracy and the robustness with which such problems can be solved in many circumstances. In this work, we concern ourselves with problems that arise in the context of many practical applications, both in manufacturing and in other areas. Specifically, it is frequently necessary to remesh a problem in the midst of an ongoing incremental loading strategy, either because of adaptive mesh refinement being used to improve resolution, or excessive mesh distortion which necessitates an overall remeshing. This work focuses on a particularly important issue associated with contact remeshing; i.e., the remapping of contact variables after the remesh so that a simulation can successfully continue. We develop and demonstrate our algorithm in the context of a mortar-discretized approach to contact. The approach is applicable to either two or three dimensional analysis, and is demonstrated by a number of three dimensional numerical examples.

  20. Concomitant contact allergy to the resins, reactive diluents and hardener of a bisphenol A/F-based epoxy resin in subway construction workers.

    Science.gov (United States)

    Chu, Chia-Yu; Pontén, Ann; Sun, Chee-Ching; Jee, Shiou-Hwa

    2006-03-01

    An outbreak of suspected contact dermatitis among subway construction workers was suspected to be due to a new bisphenol A/F-based epoxy resin system (ERS). The construction workers used ERSs during the insertion of iron bars into concrete walls. The objective of the study was to determine the components (if any) of the ERS responsible for the contact allergy. Patch testing was performed on 20 of the 22 construction workers who had had contact with the ERS, and to the various subcomponents of component A on 5 of the 7 who reacted to this component. 9 patients (9/22, 40.9%) had clinical symptoms and signs of suspected contact dermatitis at presentation. 7 of these 9, but none of the 11 asymptomatic individuals, were positive to component A, while all were negative to component B. Of the 5 cases receiving further patch testing, all reacted to m-xylylene diamine, 4 to 1,6-hexanediol diglycidyl ether, 3 to epoxy resins of the bisphenol F-type and trimethylolpropane triglycidyl ether 0.25% petrolatum, and only 1 to epoxy resins of the bisphenol A-type. Contact allergy to ERSs may involve hardeners and diluents as well as resins, and patch testing for reaction to all components should be performed.

  1. Tribological behaviour and statistical experimental design of sintered iron-copper based composites

    Science.gov (United States)

    Popescu, Ileana Nicoleta; Ghiţă, Constantin; Bratu, Vasile; Palacios Navarro, Guillermo

    2013-11-01

    The sintered iron-copper based composites for automotive brake pads have a complex composite composition and should have good physical, mechanical and tribological characteristics. In this paper, we obtained frictional composites by Powder Metallurgy (P/M) technique and we have characterized them by microstructural and tribological point of view. The morphology of raw powders was determined by SEM and the surfaces of obtained sintered friction materials were analyzed by ESEM, EDS elemental and compo-images analyses. One lot of samples were tested on a "pin-on-disc" type wear machine under dry sliding conditions, at applied load between 3.5 and 11.5 × 10-1 MPa and 12.5 and 16.9 m/s relative speed in braking point at constant temperature. The other lot of samples were tested on an inertial test stand according to a methodology simulating the real conditions of dry friction, at a contact pressure of 2.5-3 MPa, at 300-1200 rpm. The most important characteristics required for sintered friction materials are high and stable friction coefficient during breaking and also, for high durability in service, must have: low wear, high corrosion resistance, high thermal conductivity, mechanical resistance and thermal stability at elevated temperature. Because of the tribological characteristics importance (wear rate and friction coefficient) of sintered iron-copper based composites, we predicted the tribological behaviour through statistical analysis. For the first lot of samples, the response variables Yi (represented by the wear rate and friction coefficient) have been correlated with x1 and x2 (the code value of applied load and relative speed in braking points, respectively) using a linear factorial design approach. We obtained brake friction materials with improved wear resistance characteristics and high and stable friction coefficients. It has been shown, through experimental data and obtained linear regression equations, that the sintered composites wear rate increases

  2. Experimental Model Based Feedback Control for Flutter Suppression and Gust Load Alleviation Project

    Data.gov (United States)

    National Aeronautics and Space Administration — ZONA Technology, Inc. (ZONA) proposes an R&D effort to develop an Experimental Model Based Feedback Control (EMBFC) Framework for the flutter suppression and...

  3. Experimental Design for Evaluation of Co-extruded Refractory Metal/Nickel Base Superalloy Joints

    Energy Technology Data Exchange (ETDEWEB)

    ME Petrichek

    2005-12-16

    Prior to the restructuring of the Prometheus Program, the NRPCT was tasked with delivering a nuclear space reactor. Potential NRPCT nuclear space reactor designs for the Prometheus Project required dissimilar materials to be in contact with each other while operating at extreme temperatures under irradiation. As a result of the high reactor core temperatures, refractory metals were the primary candidates for many of the reactor structural and cladding components. They included the tantalum-base alloys ASTAR-811C and Ta-10W, the niobium-base alloy FS-85, and the molybdenum base alloys Moly 41-47.5 Rhenium. The refractory metals were to be joined to candidate nickel base alloys such as Haynes 230, Alloy 617, or Nimonic PE 16 either within the core if the nickel-base alloys were ultimately selected to form the outer core barrel, or at a location exterior to the core if the nickel-base alloys were limited to components exterior to the core. To support the need for dissimilar metal joints in the Prometheus Project, a co-extrusion experiment was proposed. There are several potential methods for the formation of dissimilar metal joints, including explosive bonding, friction stir welding, plasma spray, inertia welding, HIP, and co-extrusion. Most of these joining methods are not viable options because they result in the immediate formation of brittle intermetallics. Upon cooling, intermetallics form in the weld fusion zone between the joined metals. Because brittle intermetallics do not form during the initial bonding process associated with HIP, co-extrusion, and explosive bonding, these three joining procedures are preferred for forming dissimilar metal joints. In reference to a Westinghouse Astronuclear Laboratory report done under a NASA sponsored program, joints that were fabricated between similar materials via explosive bonding had strengths that were directly affected by the width of the diffusion barrier. It was determined that the diffusion zone should not exceed

  4. Spa contact dermatitis.

    Science.gov (United States)

    Yankura, Jessica A; Marks, James G; Anderson, Bryan E; Adams, David R

    2008-01-01

    Potassium monopersulfate (MPS) is widely used in spa and pool "shock" treatments, yet contact dermatitis associated with MPS has been rarely reported. A patient presented with a generalized scattered dermatitis from the neck down that worsened after spa use. Patch testing elicited a ++ reaction to ammonium persulfate. Contact with ammonium persulfate was ruled out; however, MPS, which can cross-react with ammonium persulfate, was found to be the active ingredient in the patient's spa shock treatments. The dermatitis cleared after the patient switched to a hydrogen peroxide-based shock treatment.

  5. Reliability of video-based identification of footstrike pattern and video time frame at initial contact in recreational runners

    DEFF Research Database (Denmark)

    Damsted, Camma; Larsen, L H; Nielsen, R.O.

    2015-01-01

    and video time frame at initial contact during treadmill running using two-dimensional (2D) video recordings. METHODS: Thirty-one recreational runners were recorded twice, 1 week apart, with a high-speed video camera. Two blinded raters evaluated each video twice with an interval of at least 14 days...

  6. Catalysts based on platinum–tin and platinum–gallium in close contact for the selective hydrogenation of cinnamaldehyde

    NARCIS (Netherlands)

    Plomp, A.J.|info:eu-repo/dai/nl/304837598; van Asten, D.M.P.; van der Eerden, A.M.J.|info:eu-repo/dai/nl/304840483; Mäki-Arvela, P.; Murzin, D.Y.; de Jong, K.P.|info:eu-repo/dai/nl/06885580X; Bitter, J.H.|info:eu-repo/dai/nl/160581435

    2009-01-01

    Bimetallic platinum–tin and platinum–gallium catalysts supported on carbon nanofibers (CNF) were prepared via reductive deposition precipitation and impregnation. Detailed EXAFS, TEM-EDX and XPS studies showed that reductive deposition precipitation resulted in a close contact of tin with platinum.

  7. Community Adaptation of Youth Accessing Residential Programs or a Home-Based Alternative: Contact with the Law and Delinquent Activities

    Science.gov (United States)

    Cameron, Gary; Frensch, Karen; Preyde, Michele; Quosai, Trudy Smit

    2011-01-01

    This article presents the findings from a longitudinal investigation of the prevalence of negative contact with the law for a sample of youth 12-18 months after graduating from residential and intensive children's mental health programming. Results of this study suggest serious community adaptation difficulties face many youth graduating from…

  8. A Population-Based Study of Childhood Sexual Contact in China: Prevalence and Long-Term Consequences

    Science.gov (United States)

    Luo, Ye; Parish, William L.; Laumann, Edward O.

    2008-01-01

    Objectives: This study provides national estimates of the prevalence of childhood sexual contact and its association with sexual well-being and psychological distress among adults in China. Method: A national stratified probability sample of 1,519 women and 1,475 men aged 20-64 years in urban China completed a computer-administered survey in…

  9. Composition and doping control for metal-organic chemical vapor deposition of InP-based double heterojunction bipolar transistor with hybrid base structure consisting of GaAsSb contact and InGaAsSb graded layers

    Science.gov (United States)

    Hoshi, Takuya; Kashio, Norihide; Sugiyama, Hiroki; Yokoyama, Haruki; Kurishima, Kenji; Ida, Minoru; Matsuzaki, Hideaki

    2017-07-01

    We report on a method for composition and doping control for metalorganic chemical vapor deposition of a double heterojunction bipolar transistor (DHBT) with a hybrid base structure consisting of a compositionally graded InGaAsSb for boosting an average electron velocity and a heavily doped thin GaAsSb for lowering the base contact resistivity. The GaAsSb contact layer can be formed by simply turning off the supply of In precursor tetramethylindium (TMIn) after the growth of the composition and doping graded InGaAsSb base. Consequently, the solid composition and hole concentration of hybrid base can be properly controlled by just modulating the supply of only TMIn and carbon tetrabromide. Secondary ion mass spectroscopy for the DHBT wafer reveals that the contents of In, Ga, and C inside the base are actually modulated from the collector side to the emitter side as expected. Transmission-line-model measurements were performed for the compositionally graded-InGaAsSb/GaAsSb hybrid base. The contact resistivity is estimated to be 5.3 Ω µm2, which is lower than half the value of a compositionally graded InGaAsSb base without the GaAsSb contact layer. The results indicate that the compositionally-graded-InGaAsSb/GaAsSb-contact hybrid base structure grown by this simple method is very advantageous for obtaining DHBTs with a very high maximum oscillation frequency.

  10. Reform and practice for photoelectric specialty experimental teaching based on virtual simulation experiment platform

    Science.gov (United States)

    Ye, Yan; Lv, Qingsong; Wu, Maocheng; Xu, Yishen; Gu, Jihua

    2017-08-01

    has been improved greatly. In the next time, based on the development trend of optoelectronic discipline and our own major characteristics, we will further perfect and enrich the construction of virtual simulation experimental platform and continuously improve the quality of experimental teaching.

  11. Contact Allergy To Hard Contact Lens

    Directory of Open Access Journals (Sweden)

    J S Pasricha

    1985-01-01

    Full Text Available Three patients developed recurrent irritation, redness and watery discharge from their eyes after using hard contact lens. Patch tests were positive with the material of the hard contact lens and negative with teepol, sodium lauryl sulphate and material of the soft contact lens. All the three patients became alright after they stopped,using hard contact lens.

  12. ALLERGIC CONTACT DERMATITIS

    Directory of Open Access Journals (Sweden)

    Trisna Yuliharti Tersinanda

    2013-07-01

    Full Text Available Normal 0 false false false EN-US X-NONE X-NONE Allergic contact dermatitis is an immunologic reaction that tends to involve the surrounding skin and may even spread beyond affected sites. This skin disease is one of the more frequent, and costly dermatologic problems. Recent data from United Kingdom and United States suggest that the percentage of occupational contact dermatitis due to allergy may be much higher, thus raising the economic impact of occupational allergic contact dermatitis. There is not enough data about the epidemiology of allergic contact dermatitis in Indonesia, however based on research that include beautician in Denpasar, about 27,6 percent had side effect of cosmetics, which is 25,4 percent of it manifested as allergic contact dermatitis. Diagnosis of allergic contact dermatitis is based on anamnesis, physical examination, patch test, and this disease should be distinguished from other eczematous skin disease. The management is prevention of allergen exposure, symptomatic treatment, and physicochemical barrier /* Style Definitions */ table.MsoNormalTable {mso-style-name:"Table Normal"; mso-tstyle-rowband-size:0; mso-tstyle-colband-size:0; mso-style-noshow:yes; mso-style-priority:99; mso-style-qformat:yes; mso-style-parent:""; mso-padding-alt:0in 5.4pt 0in 5.4pt; mso-para-margin-top:0in; mso-para-margin-right:0in; mso-para-margin-bottom:10.0pt; mso-para-margin-left:0in; line-height:115%; mso-pagination:widow-orphan; font-size:11.0pt; font-family:"Calibri","sans-serif"; mso-ascii-font-family:Calibri; mso-ascii-theme-font:minor-latin; mso-fareast-font-family:"Times New Roman"; mso-fareast-theme-font:minor-fareast; mso-hansi-font-family:Calibri; mso-hansi-theme-font:minor-latin; mso-bidi-font-family:"Times New Roman"; mso-bidi-theme-font:minor-bidi;}

  13. Lipstick Induced Contact Leucoderma

    Directory of Open Access Journals (Sweden)

    Gupta Lalit Kumar

    2001-01-01

    Full Text Available Lipstick is a commonly used cosmetic. Its use may sometimes lead to contact dermatitis. Contact leucoderma to lipsticks however, is not common. We report a patient developing contact leucoderma to lipstick in association with contact dermatitis.

  14. Lipstick Induced Contact Leucoderma

    OpenAIRE

    Gupta Lalit Kumar; Jain Suresh Kumar; Khare Ashok Kumar

    2001-01-01

    Lipstick is a commonly used cosmetic. Its use may sometimes lead to contact dermatitis. Contact leucoderma to lipsticks however, is not common. We report a patient developing contact leucoderma to lipstick in association with contact dermatitis.

  15. Biofilm formation by Staphylococcus aureus from food contact surfaces in a meat-based broth and sensitivity to sanitizers

    Directory of Open Access Journals (Sweden)

    Evandro Leite de Souza

    2014-01-01

    Full Text Available This study assessed the capacity of adhesion, the detachment kinetic and the biofilm formation by Staphylococcus aureus isolated from food services on stainless steel and polypropylene surfaces (2 x 2 cm when cultivated in a meat-based broth at 28 and 7 ºC. It was also to study the efficacy of the sanitizers sodium hypochlorite (250 mg/L and peracetic acid (30 mg/L in inactivating the bacterial cells in the preformed biofilm. S. aureus strains adhered in high numbers regardless the assayed surface kind and incubation temperature over 72 h. Cells detachment of surfaces revealed high persistence over the incubation period. Number of cells needed for biofilm formation was noted at all experimental systems already after 3 days. Peracetic acid and sodium hypochlorite were not efficient in completely removing the cells of S. aureus adhered on polypropylene and stainless steel surfaces. From these results, the assayed strains revealed high capacity to adhere and form biofilm on polypropylene and stainless steel surfaces under different growth conditions. Moreover, the cells in biofilm matrix were resistant for total removal when submitted to the exposure to sanitizers.

  16. The Influence of Evidence-Based Surgical Indications and Techniques on Failure Rates After Arthroscopic Shoulder Stabilization in the Contact or Collision Athlete With Anterior Shoulder Instability.

    Science.gov (United States)

    Leroux, Timothy S; Saltzman, Bryan M; Meyer, Maximilian; Frank, Rachel M; Bach, Bernard R; Cole, Brian J; Romeo, Anthony A; Verma, Nikhil N

    2017-04-01

    It has been reported that arthroscopic shoulder stabilization yields higher rates of failure in contact or collision athletes as compared with open shoulder stabilization; however, this is largely based upon studies that do not employ modern, evidence-based surgical indications and techniques for arthroscopic shoulder stabilization. To (1) determine the pooled failure rate across all studies reporting failure after primary arthroscopic shoulder stabilization for anterior shoulder instability in contact or collision athletes and (2) stratify failure rates according to studies that use evidence-based surgical indications and techniques. Systematic review. A review of PubMed, Medline, and Embase was performed to identify all clinical studies with a minimum of 1-year follow-up that reported failure rates after arthroscopic shoulder stabilization for anterior shoulder instability in contact or collision athletes. Data pertaining to patient demographics, clinical and radiographic preoperative assessment, surgical indications, surgical technique, rehabilitation, and outcome were collected from each included study. An overall failure rate was determined across all included studies. After this, a secondary literature review was performed to identify factors related to patient selection and surgical technique that significantly influence failure after primary arthroscopic shoulder stabilization. Failure rates were then determined among included studies that used these evidence-based indications and techniques. Overall, 26 studies reporting on 779 contact or collision athletes met the inclusion criteria. The mean patient age was 19.9 years, 90.3% were male, and the most common sport was rugby. There was considerable variability in the reporting of patient demographics, preoperative assessment, surgical indications, surgical technique, and patient outcomes. Across all included studies, the pooled failure rate after arthroscopic shoulder stabilization in the contact or

  17. Open-cycle magnetohydrodynamic power plant based upon direct-contact closed-loop high-temperature heat exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Berry, Gregory F. (Naperville, IL); Minkov, Vladimir (Skokie, IL); Petrick, Michael (Joliet, IL)

    1988-01-01

    A magnetohydrodynamic (MHD) power generating system in which ionized combustion gases with slag and seed are discharged from an MHD combustor and pressurized high temperature inlet air is introduced into the combustor for supporting fuel combustion at high temperatures necessary to ionize the combustion gases, and including a heat exchanger in the form of a continuous loop with a circulating heat transfer liquid such as copper oxide. The heat exchanger has an upper horizontal channel for providing direct contact between the heat transfer liquid and the combustion gases to cool the gases and condense the slag which thereupon floats on the heat transfer liquid and can be removed from the channel, and a lower horizontal channel for providing direct contact between the heat transfer liquid and pressurized air for preheating the inlet air. The system further includes a seed separator downstream of the heat exchanger.

  18. Open-cycle magnetohydrodynamic power plant based upon direct-contact closed-loop high-temperature heat exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Berry, Gregory F.; Minkov, Vladimir; Petrick, Michael

    1988-01-05

    A magnetohydrodynamic (MHD) power generating system in which ionized combustion gases with slag and seed are discharged from an MHD combustor and pressurized high temperature inlet air is introduced into the combustor for supporting fuel combustion at high temperatures necessary to ionize the combustion gases, and including a heat exchanger in the form of a continuous loop with a circulating heat transfer liquid such as copper oxide. The heat exchanger has an upper horizontal channel for providing direct contact between the heat transfer liquid and the combustion gases to cool the gases and condense the slag which thereupon floats on the heat transfer liquid and can be removed from the channel, and a lower horizontal channel for providing direct contact between the heat transfer liquid and pressurized air for preheating the inlet air. The system further includes a seed separator downstream of the heat exchanger.

  19. A surface-micromachining-based inertial micro-switch with compliant cantilever beam as movable electrode for enduring high shock and prolonging contact time

    Energy Technology Data Exchange (ETDEWEB)

    Xu, Qiu [National Key Laboratory of Science and Technology on Micro/Nano Fabrication, School of Electronics Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240 (China); Yang, Zhuoqing, E-mail: yzhuoqing@sjtu.edu.cn [National Key Laboratory of Science and Technology on Micro/Nano Fabrication, School of Electronics Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240 (China); Fu, Bo; Li, Jianhua; Wu, Hao [Huaihai Industrial Group Co., Ltd., Changzhi, Shanxi Province, 046012 (China); Zhang, Qihuan; Sun, Yunna; Ding, Guifu; Zhao, Xiaolin [National Key Laboratory of Science and Technology on Micro/Nano Fabrication, School of Electronics Information and Electrical Engineering, Shanghai Jiao Tong University, Shanghai, 200240 (China)

    2016-11-30

    Highlights: • The designed cantilever beam attached to the proof mass can endure a larger shock acceleration (∼1000 g order of magnitude) compared to those traditional designs (∼100 g order of magnitude). • Effect of the pulse width on the threshold acceleration, the response time and the contact time is investigated. • A constraint sleeve structure is introduced to lower the off-axis sensitivity. - Abstract: A novel laterally-driven inertial micro-switch with two L-shaped elastic cantilever beams as the movable electrode, which is attached to the proof mass, is proposed in this paper. The advantage of this design is that the contact time of the inertial micro-switch can be prolonged. Meanwhile, the micro-switch can withstand a higher shock than the traditional designs whose cantilever beams are attached to the fixed electrode. The designed inertial micro-switch was simulated and optimized with ANSYS software and fabricated on a quartz substrate by surface micromachining technology. The simulated result demonstrates that the threshold acceleration (a{sub ths}) under stable switch-on state is about 288 g and the contact time is about 198 μs when the pulse width of acceleration loads is 1 ms. At the same time, it indicates that the threshold acceleration, the response time and the contact time of designed micro-switch all increase with the pulse width of acceleration loads. The simulation of impact process in non-sensitive direction shows that the introduced constraint sleeve structure in the novel inertial micro-switch can lower the off-axis sensitivity. The fabricated micro-switch prototype has been tested by a standard dropping hammer system under shock accelerations with various amplitudes and pulse widths. The experimental measurements show that the contact time is about 150 μs when the threshold acceleration is about 288 g. It also indicates that the response time and the contact time both increase with the pulse width, which is consistent with the

  20. Evaluation of Surface Fatigue Strength Based on Surface Temperature (Surface Temperature Calculation for Rolling-Sliding Contact)

    OpenAIRE

    鄧, 鋼; 中西, 勉

    2001-01-01

    Surface temperature is considered as an integrated index which is a combined result of not only the load and dimensions at the contact point but also the sliding velocity, rolling velocity, surface roughness, lubrication condition and etc.. So, the surface durability of such as roller and gear will be evaluated more exactly and simply by use of the surface temperature than Hertzian stress. In this research, the surface temperatures of rollers under different rolling and sliding conditions are...

  1. Perovskite/silicon-based heterojunction tandem solar cells with 14.8% conversion efficiency via adopting ultrathin Au contact

    Science.gov (United States)

    Fan, Lin; Wang, Fengyou; Liang, Junhui; Yao, Xin; Fang, Jia; Zhang, Dekun; Wei, Changchun; Zhao, Ying; Zhang, Xiaodan

    2017-01-01

    A rising candidate for upgrading the performance of an established narrow-bandgap solar technology without adding much cost is to construct the tandem solar cells from a crystalline silicon bottom cell and a high open-circuit voltage top cell. Here, we present a four-terminal tandem solar cell architecture consisting of a self-filtered planar architecture perovskite top cell and a silicon heterojunction bottom cell. A transparent ultrathin gold electrode has been used in perovskite solar cells to achieve a semi-transparent device. The transparent ultrathin gold contact could provide a better electrical conductivity and optical reflectance-scattering to maintain the performance of the top cell compared with the traditional metal oxide contact. The four-terminal tandem solar cell yields an efficiency of 14.8%, with contributions of the top (8.98%) and the bottom cell (5.82%), respectively. We also point out that in terms of optical losses, the intermediate contact of self-filtered tandem architecture is the uppermost problem, which has been addressed in this communication, and the results show that reducing the parasitic light absorption and improving the long wavelength range transmittance without scarifying the electrical properties of the intermediate hole contact layer are the key issues towards further improving the efficiency of this architecture device. Project supported by the International Cooperation Projects of the Ministry of Science and Technology (No. 2014DFE60170), the National Natural Science Foundation of China (Nos. 61474065, 61674084), the Tianjin Research Key Program of Application Foundation and Advanced Technology (No. 15JCZDJC31300), the Key Project in the Science & Technology Pillar Program of Jiangsu Province (No. BE2014147-3), and the 111 Project (No. B16027).

  2. LABEXNET: un Laboratorio de Economía Experimental en Internet. [LABEXNET: Internet-based laboratory for experimental Economics

    Directory of Open Access Journals (Sweden)

    Galán Ordax, José Manuel

    2007-06-01

    Full Text Available Experimental Economists have designed over the years a wide range of scientific experiments that can be usefully employed nowadays as teaching aids. The interactive and participatory nature of such experiments serves as a motivation to students, stimulates their own thinking, and enhances their insights into the forces that drive economic markets: the aggregate interactions of economic agents within a market institution. Economic classroom games have been recognised as useful teaching tools for decades, and they have often produced surprising results and better understanding of market dynamics and institutions. Nowadays the new information technologies can be brought into play to conduct and analyse experimental games in unprecedented ways: using Internet-based tools, the design, execution and analysis of classroom games can be made considerably easier than traditionally. In this paper we introduce LABEXNET, a program designed to conduct Internet-based economic classroom games. LABEXNET is freely available to the academic community.. La Economía Experimental ha desarrollado diferentes experimentos que pueden ser aprovechados como una actividad docente en la enseñanza de la Economía. Su naturaleza activa y participativa motiva a los alumnos y estimula la reflexión y la mejor comprensión de algunos fenómenos económicos como el funcionamiento de los mercados, donde los resultados individuales dependen del conjunto de las decisiones de los agentes y de sus interacciones. Los experimentos económicos tienen ya una larga tradición, y han proporcionado resultados espectaculares y conclusiones ampliamente admitidas sobre la dinámica de mercados y el efecto de las instituciones económicas. Las nuevas tecnologías facilitan la realización y el análisis de estos experimentos. En este artículo presentamos LABEXNET, un programa informático para la realización de experimentos económicos por Internet puesto a libre disposición de la comunidad

  3. Common Allergens Identified Based on Patch Test Results in Patients with Suspected Contact Dermatitis of the Scalp

    Science.gov (United States)

    Aleid, Nouf M.; Fertig, Raymond; Maddy, Austin; Tosti, Antonella

    2017-01-01

    Background Contact dermatitis of the scalp is common and might be caused by many chemicals including metals, ingredients of shampoos and conditioners, dyes, or other hair treatments. Eliciting a careful history and patch tests are necessary to identify the responsible allergen and prevent relapses. Objectives To identify allergens that may cause contact dermatitis of the scalp by reviewing patch test results. Methods We reviewed the records of 1,015 patients referred for patch testing at the Dermatology Department of the University of Miami. A total of 226 patients (205 females and 21 males) with suspected scalp contact dermatitis were identified, and the patch test results and clinical data for those patients were analyzed. Most patients were referred for patch testing from a specialized hair clinic at our institution. Results The most common allergens in our study population were nickel (23.8%), cobalt (21.0%), balsam of Peru (18.2%), fragrance mix (14.4%), carba mix (11.6%), and propylene glycol (PG) (8.8%). The majority of patients were females aged 40–59 years, and scalp itching or burning were reported as the most common symptom. Conclusion Frequent sources of allergens for metals include hair clasps, pins, and brushes, while frequent sources of allergens for preservatives, fragrance mix, and balsam of Peru include shampoos, conditioners, and hair gels. Frequent sources of allergens for PG include topical medications. PMID:28611994

  4. Silicon Based Photovoltaic Cells For Concentration-Research And Development Progress In Laser Grooved Buried Contact Cell Technology

    Science.gov (United States)

    Cole, A.; Baistow, I.; Brown, L.; Devenport, S.; Drew, K.; Heasman, K. C.; Morrison, D.; Bruton, T. M.; Serenelli, L.; De Iuliis, S.; Izzi, M.; Tucci, M.; Salza, E.; Pirozzi, L.

    2011-12-01

    The Laser grooved buried contact silicon solar cell (LGBC) process employed by Narec currently produces LGBC cells designed to operate at concentrations ranging from 1-100 suns and has demonstrated efficiencies at 50X of over 19% and at 100X of over 18.2% using 300 μm CZ silicon[1] wafers. As part of the LAB2LINE[1], APOLLON[2] and ASPIS[3] projects funded under the European Commission Framework Programs (FP6 and FP7) we have made improvements to the LGBC process to improve efficiency or make the cell technology more suitable for industrial CPV receiver manufacturing processes. We describe a process which hybridizes LGBC and more standard screen printing technologies which yields at least a 6% relative improvement at concentration when using more readily available 200 μm thick CZ wafers. We describe a pioneering front dicing technique (FDT). The FDT process is important in small cells where edge recombination effects are detrimental to the performance. We show that by using this new technique we can produce cells that perform better at concentration and improve the positioning of the front contact of the cell. We also describe a busbar technology that uses laser processing and electroless chemical plating to allow not only soldering to the front contact of the cell but also wire bonding. The advances in research and development of LGBC cells leading to improved cell performance may provide significant reductions in levilised cost of energy (LCOE) for low to medium CPV systems.

  5. Structural changes of electron and ion beam-deposited contacts in annealed carbon-based electrical devices

    KAUST Repository

    Batra, Nitin M

    2015-10-09

    The use of electron and ion beam deposition to make devices containing discrete nanostructures as interconnectors is a well-known nanofabrication process. Classically, one-dimensional materials such as carbon nanotubes (CNTs) have been electrically characterized by resorting to these beam deposition methods. While much attention has been given to the interconnectors, less is known about the contacting electrodes (or leads). In particular, the structure and chemistry of the electrode–interconnector interface is a topic that deserves more attention, as it is critical to understand the device behavior. Here, the structure and chemistry of Pt electrodes, deposited either with electron or ion beams and contacted to a CNT, are analyzed before and after thermally annealing the device in a vacuum. Free-standing Pt nanorods, acting as beam-deposited electrode models, are also characterized pre- and post-annealing. Overall, the as-deposited leads contain a non-negligible amount of amorphous carbon that is consolidated, upon heating, as a partially graphitized outer shell enveloping a Pt core. This observation raises pertinent questions regarding the definition of electrode–nanostructure interfaces in electrical devices, in particular long-standing assumptions of metal-CNT contacts fabricated by direct beam deposition methods.

  6. An ultra-bright white LED based non-contact skin cancer imaging system with polarization control

    Science.gov (United States)

    Günther, A.; Basu, C.; Roth, B.; Meinhardt-Wollweber, M.

    2013-06-01

    Early detection and excision of melanoma skin cancer is crucial for a successful therapy. Dermoscopy in direct contact with the skin is routinely used for inspection, but screening is time consuming for high-risk patients with a large number of nevi. Features like symmetry, border, color and most importantly changes like growth or depigmentation of a nevus may indicate malignancy. We present a non-contact remote imaging system for human melanocytic nevi with homogenous illumination by an ultra-bright white LED. The advantage compared to established dermoscopy systems requiring direct skin contact is that deformation of raised nevi is avoided and full-body scans of the patients may time-efficiently be obtained while they are in a lying, comfortable position. This will ultimately allow for automated screening in the future. In addition, calibration of true color rendering, which is essential for distinguishing between benign and malignant lesions and to ensure reproducibility and comparison between individual check-ups in order to follow nevi evolution is implemented as well as suppression of specular highlights on the skin surface by integration of polarizing filters. Important features of the system which will be crucial for future integration into automated systems are the possibility to record images without artifacts in combination with short exposure times which both reduce image blurring caused by patient motion.

  7. A Study of a Handrim-Activated Power-Assist Wheelchair Based on a Non-Contact Torque Sensor

    Directory of Open Access Journals (Sweden)

    Ki-Tae Nam

    2016-08-01

    Full Text Available Demand for wheelchairs is increasing with growing numbers of aged and disabled persons. Manual wheelchairs are the most commonly used assistive device for mobility because they are convenient to transport. Manual wheelchairs have several advantages but are not easy to use for the elderly or those who lack muscular strength. Therefore, handrim-activated power-assist wheelchairs (HAPAW that can aid driving power with a motor by detecting user driving intentions through the handrim are being researched. This research will be on HAPAW that judge user driving intentions by using non-contact torque sensors. To deliver the desired motion, which is sensed from handrim rotation relative to a fixed controller, a new driving wheel mechanism is designed by applying a non-contact torque sensor, and corresponding torques are simulated. Torques are measured by a driving wheel prototype and compared with simulation results. The HAPAW prototype was developed using the wheels and a driving control algorithm that uses left and right input torques and time differences are used to check if the non-contact torque sensor can distinguish users’ driving intentions. Through this procedure, it was confirmed that the proposed sensor can be used effectively in HAPAW.

  8. Fabricating customized hydrogel contact lens

    Science.gov (United States)

    Childs, Andre; Li, Hao; Lewittes, Daniella M.; Dong, Biqin; Liu, Wenzhong; Shu, Xiao; Sun, Cheng; Zhang, Hao F.

    2016-10-01

    Contact lenses are increasingly used in laboratories for in vivo animal retinal imaging and pre-clinical studies. The lens shapes often need modification to optimally fit corneas of individual test subjects. However, the choices from commercially available contact lenses are rather limited. Here, we report a flexible method to fabricate customized hydrogel contact lenses. We showed that the fabricated hydrogel is highly transparent, with refractive indices ranging from 1.42 to 1.45 in the spectra range from 400 nm to 800 nm. The Young’s modulus (1.47 MPa) and hydrophobicity (with a sessile drop contact angle of 40.5°) have also been characterized experimentally. Retinal imaging using optical coherence tomography in rats wearing our customized contact lenses has the quality comparable to the control case without the contact lens. Our method could significantly reduce the cost and the lead time for fabricating soft contact lenses with customized shapes, and benefit the laboratorial-used contact lenses in pre-clinical studies.

  9. Experimental research on combustion fluorine retention using calcium-based sorbets during coal combustion (I)

    Energy Technology Data Exchange (ETDEWEB)

    Qi, Qing-jie; Lin, Zhi-yan; Liu, Jian-zhong; Wu, Xian; Zhou, Jun-hu; Cen, Ke-fa [Liaoning Technical University, Fuxin (China). College of Resource and Environment Engineering

    2008-06-15

    In order to provide experimental guide to commercial use of fluorine pollution control during coal combustion, with fluorine pollution control during coal combustion in mind, this paper proposed the theory of combustion fluorine retention technology. Feasibility of fluorine retention reaction with calcium-based fluorine retention agent was analyzed through thermodynamic calculation during coal combustion. By simulating the restraining and retention effects and influential factors of calcium-based sorbets on vaporized fluoride during experimental combustion using fixed bed tube furnace, the paper systematically explored the influential law of such factors as combustion temperature, retention time, and added quantities of calcium-based sorbets on effects of fluorine retention. The research result shows that adding calcium-based fluorine retention agent in coal combustion has double effects of fluorine retention and sulfur retention, it lays an experimental foundation for commercial test of combustion fluorine retention. 7 refs., 2 figs., 4 tabs.

  10. Experimental Research of HF Passive Radar Based on DRM Digital AM Broadcasting

    Directory of Open Access Journals (Sweden)

    Wan Xian-rong

    2012-03-01

    Full Text Available This paper gives the experimental research of HF Passive Bistatic Radar (HFPBR based on Digital Radio Mondiale (DRM digital AM broadcasting that have been first carried out in China, using the newly-developed all-digital active/passive integrated HF surface wave radar system. The principle, key techniques, experimental equipment, and preliminary results are introduced about this new radar system. Based on analysis of the measurement data, experimental results under different scenarios including surface-wave, sky-wave, and hybrid sky-surface propagation modes are presented, which have proved, for the first time worldwide, the technical feasibility of using DRM broadcasting signal for over-the-horizon detection by field experiment and formed the theoretical and experimental basis for the further development of HFPBR.

  11. Experimental and theoretical demonstration of amplifying pulse compression using an SOA- based Mach-Zehnder Interferometer

    DEFF Research Database (Denmark)

    Nielsen, Mads Lønstrup; Dagens, B.

    2004-01-01

    A pulse compression scheme based on a semiconductor optical amplifier -(SOA)based Mach-Zehnder interferometer (MZI) is proposed. It is independent of the initial chirp of the pulses, provides amplification, and can potentially be integrated with a simple pulse source. Experimental demonstration...

  12. Power-Based Setpoint Control : Experimental Results on a Planar Manipulator

    NARCIS (Netherlands)

    Dirksz, D. A.; Scherpen, J. M. A.

    In the last years the power-based modeling framework, developed in the sixties to model nonlinear electrical RLC networks, has been extended for modeling and control of a larger class of physical systems. In this brief we apply power-based integral control to a planar manipulator experimental setup.

  13. Prediction of sonic boom from experimental near-field overpressure data. Volume 2: Data base construction

    Science.gov (United States)

    Glatt, C. R.; Reiners, S. J.; Hague, D. S.

    1975-01-01

    A computerized method for storing, updating and augmenting experimentally determined overpressure signatures has been developed. A data base of pressure signatures for a shuttle type vehicle has been stored. The data base has been used for the prediction of sonic boom with the program described in Volume I.

  14. Software-defined Radio Based Wireless Tomography: Experimental Demonstration and Verification

    Energy Technology Data Exchange (ETDEWEB)

    Bonior, Jason D [ORNL; Hu, Zhen [Tennessee Technological University; Guo, Terry N. [Tennessee Technological University; Qiu, Robert C. [Tennessee Technological University; Browning, James P. [United States Air Force Research Laboratory, Wright-Patterson Air Force Base; Wicks, Michael C. [University of Dayton Research Institute

    2015-01-01

    This letter presents an experimental demonstration of software-defined-radio-based wireless tomography using computer-hosted radio devices called Universal Software Radio Peripheral (USRP). This experimental brief follows our vision and previous theoretical study of wireless tomography that combines wireless communication and RF tomography to provide a novel approach to remote sensing. Automatic data acquisition is performed inside an RF anechoic chamber. Semidefinite relaxation is used for phase retrieval, and the Born iterative method is utilized for imaging the target. Experimental results are presented, validating our vision of wireless tomography.

  15. Drug loading optimization and extended drug delivery of corticoids from pHEMA based soft contact lenses hydrogels via chemical and microstructural modifications.

    Science.gov (United States)

    García-Millán, Eva; Koprivnik, Sandra; Otero-Espinar, Francisco Javier

    2015-06-20

    This paper proposes an approach to improve drug loading capacity and release properties of poly(2-hydroxyethyl methacrylate) (p(HEMA)) soft contact lenses based on the optimization of the hydrogel composition and microstructural modifications using water during the polymerization process. P(HEMA) based soft contact lenses were prepared by thermal or photopolymerization of 2-hydroxyethyl methacrylate (HEMA) solutions containing ethylene glycol di-methacrylate as crosslinker and different proportions of N-vinyl-2-pyrrolidone (NVP) or methacrylic acid (MA) as co-monomers. Transmittance, water uptake, swelling, microstructure, drug absorption isotherms and in vitro release were characterized using triamcinolone acetonide (TA) as model drug. Best drug loading ratios were obtained with lenses containing the highest amount (200 mM) of MA. Incorporation of 40% V/V of water during the polymerization increases the hydrogel porosity giving a better drug loading capacity. In vitro TA release kinetics shows that MA hydrogels released the drug significantly faster than NVP-hydrogels. Drug release was found to be diffusion controlled and kinetics was shown to be reproducible after consecutive drug loading/release processes. Results of p(HEMA) based soft contact lenses copolymerized with ethylene glycol dimethacrylate (EGDMA) and different co-monomers could be a good alternative to optimize the loading and ocular drug delivery of this corticosteroid drug. Copyright © 2015. Published by Elsevier B.V.

  16. Experimental study of thermophysical properties of thin-film coatings based on hollow microspheres

    Science.gov (United States)

    Bukhmirov, V. V.; Gaskov, A. K.

    2017-11-01

    The paper describes results of an experimental study of thermal properties of energy-efficient thin-film coatings based on hollow glass microspheres MS-V2L in a styrene acrylic dispersion binder «Akrilan 101». A value of energy-efficient paint thermal conductivity depending on its composition and temperature and a value of the thermal diffusivity of the paint were experimentally determined. Data on the energy saving paint density and specific heat capacity were also obtained.

  17. Reducing experimental variability in variance-based sensitivity analysis of biochemical reaction systems.

    Science.gov (United States)

    Zhang, Hong-Xuan; Goutsias, John

    2011-03-21

    Sensitivity analysis is a valuable task for assessing the effects of biological variability on cellular behavior. Available techniques require knowledge of nominal parameter values, which cannot be determined accurately due to experimental uncertainty typical to problems of systems biology. As a consequence, the practical use of existing sensitivity analysis techniques may be seriously hampered by the effects of unpredictable experimental variability. To address this problem, we propose here a probabilistic approach to sensitivity analysis of biochemical reaction systems that explicitly models experimental variability and effectively reduces the impact of this type of uncertainty on the results. The proposed approach employs a recently introduced variance-based method to sensitivity analysis of biochemical reaction systems [Zhang et al., J. Chem. Phys. 134, 094101 (2009)] and leads to a technique that can be effectively used to accommodate appreciable levels of experimental variability. We discuss three numerical techniques for evaluating the sensitivity indices associated with the new method, which include Monte Carlo estimation, derivative approximation, and dimensionality reduction based on orthonormal Hermite approximation. By employing a computational model of the epidermal growth factor receptor signaling pathway, we demonstrate that the proposed technique can greatly reduce the effect of experimental variability on variance-based sensitivity analysis results. We expect that, in cases of appreciable experimental variability, the new method can lead to substantial improvements over existing sensitivity analysis techniques.

  18. Contact pin-printing of albumin-fungicide conjugate for silicon nitride-based sensors biofunctionalization: Multi-technique surface analysis for optimum immunoassay performance

    Energy Technology Data Exchange (ETDEWEB)

    Gajos, Katarzyna, E-mail: katarzyna.gajos@doctoral.uj.edu.pl [M. Smoluchowski Institute of Physics, Jagiellonian University, Łojasiewicza, 11, 30-348 Kraków (Poland); Budkowski, Andrzej [M. Smoluchowski Institute of Physics, Jagiellonian University, Łojasiewicza, 11, 30-348 Kraków (Poland); Tsialla, Zoi; Petrou, Panagiota [Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR Demokritos, P. Grigoriou & Neapoleos St., Aghia Paraksevi 15310, Athens (Greece); Awsiuk, Kamil; Dąbczyński, Paweł [M. Smoluchowski Institute of Physics, Jagiellonian University, Łojasiewicza, 11, 30-348 Kraków (Poland); Bernasik, Andrzej [Faculty of Physics and Applied Computer Science, AGH University of Science and Technology, Mickiewicza 30, 30-059 Kraków (Poland); Academic Centre for Materials and Nanotechnology, AGH University of Science and Technology, Mickiewicza 30, 30-059 Kraków (Poland); Rysz, Jakub [M. Smoluchowski Institute of Physics, Jagiellonian University, Łojasiewicza, 11, 30-348 Kraków (Poland); Misiakos, Konstantinos; Raptis, Ioannis [Department of Microelectronics, Institute of Nanoscience and Nanotechnology, NCSR Demokritos, P. Grigoriou & Neapoleos St., Aghia Paraksevi 15310, Athens (Greece); Kakabakos, Sotirios [Institute of Nuclear & Radiological Sciences & Technology, Energy & Safety, NCSR Demokritos, P. Grigoriou & Neapoleos St., Aghia Paraksevi 15310, Athens (Greece)

    2017-07-15

    Highlights: • Contact pin-printing of overlapping probe spots and spotting by hand are compared. • Contact pin-printing favors probe immobilization with two-fold higher surface density. • Incomplete monolayer develops to bilayer as printing solution concentration increases. • Blocking molecules complete probe monolayer but reduce probe bilayer. • Surface immunoreaction increases with probe concentration in printing solution. - Abstract: Mass fabrication of integrated biosensors on silicon chips is facilitated by contact pin-printing, applied for biofunctionalization of individual Si{sub 3}N{sub 4}-based transducers at wafer-scale. To optimize the biofunctionalization for immunochemical (competitive) detection of fungicide thiabendazole (TBZ), Si{sub 3}N{sub 4} surfaces are modified with (3-aminopropyl)triethoxysilane and examined after: immobilization of BSA-TBZ conjugate (probe) from solutions with different concentration, blocking with bovine serum albumin (BSA), and immunoreaction with a mouse monoclonal antibody against TBZ. Nanostructure, surface density, probe composition and coverage uniformity of protein layers are evaluated with Atomic Force Microscopy, Spectroscopic Ellipsometry, Time-of-Flight Secondary Ion Mass Spectrometry and X-ray Photoelectron Spectroscopy. Contact pin-printing of overlapping probe spots is compared with hand spotted areas. Contact pin-printing resulted in two-fold increase of immobilized probe surface density as compared to hand spotting. Regarding BSA-TBZ immobilization, an incomplete monolayer develops into a bilayer as the concentration of BSA-TBZ molecules in the printing solution increases from 25 to 100 μg/mL. Upon blocking, however, a complete protein monolayer is formed for all the BSA-TBZ concentrations used. Free surface sites are filled with BSA for low surface coverage with BSA-TBZ, whereas loosely bound BSA-TBZ molecules are removed from the BSA-TBZ bilayer. As a consequence immunoreaction efficiency

  19. Reliability of video-based identification of footstrike pattern and video time frame at initial contact in recreational runners.

    Science.gov (United States)

    Damsted, C; Larsen, L H; Nielsen, R O

    2015-06-01

    Two-dimensional video recordings are used in clinical practice to identify footstrike pattern. However, knowledge about the reliability of this method of identification is limited. To evaluate intra- and inter-rater reliability of visual identification of footstrike pattern and video time frame at initial contact during treadmill running using two-dimensional (2D) video recordings. Thirty-one recreational runners were recorded twice, 1 week apart, with a high-speed video camera. Two blinded raters evaluated each video twice with an interval of at least 14 days. Kappa values for within-day identification of footstrike pattern revealed intra-rater agreement of 0.83-0.88 and inter-rater agreement of 0.50-0.63. Corresponding figures for between-day identification of footstrike pattern were 0.63-0.69 and 0.41-0.53, respectively. Identification of video time frame at initial contact ranged from five frames to 12 frames (95% limits of agreement). For clinical use, the intra-rater within-day identification of footstrike pattern is highly reliable (kappa>0.80). For the inter-rater between-day identification inconsistencies may, in worst case, occur in 36% of the identifications (kappa=0.41). The 95% limits of agreement for identification of video time frame at initial contact may, at times, allow for different identification of footstrike pattern. Clinicians should, therefore, be encouraged to continue using clinical 2D video setups for intra-rater identification of footstrike pattern, but bear in mind the restrictions related to the between day identifications. Copyright © 2015 Elsevier B.V. All rights reserved.

  20. Electromagnetic Vortex-Based Radar Imaging Using a Single Receiving Antenna: Theory and Experimental Results.

    Science.gov (United States)

    Yuan, Tiezhu; Wang, Hongqiang; Cheng, Yongqiang; Qin, Yuliang

    2017-03-19

    Radar imaging based on electromagnetic vortex can achieve azimuth resolution without relative motion. The present paper investigates this imaging technique with the use of a single receiving antenna through theoretical analysis and experimental results. Compared with the use of multiple receiving antennas, the echoes from a single receiver cannot be used directly for image reconstruction using Fourier method. The reason is revealed by using the point spread function. An additional phase is compensated for each mode before imaging process based on the array parameters and the elevation of the targets. A proof-of-concept imaging system based on a circular phased array is created, and imaging experiments of corner-reflector targets are performed in an anechoic chamber. The azimuthal image is reconstructed by the use of Fourier transform and spectral estimation methods. The azimuth resolution of the two methods is analyzed and compared through experimental data. The experimental results verify the principle of azimuth resolution and the proposed phase compensation method.

  1. [Breastfeeding counseling and early mother-child contact are associated with exclusive maternal breastfeeding. A hospital-based-case-control study].

    Science.gov (United States)

    González-Salazar, Francisco; Cerda-Flores, Ricardo M; Robledo-García, José A; Valdovinos-Chávez, Salvador; Vargas-Villarreal, Javier; Said-Fernández, Salvador

    2005-01-01

    The aim of this study was to assess the association between exclusive breastfeeding (EBF) and some factors that may influence breastfeeding in a closely related population attending a private hospital sponsored by a major Mexican brewing company. We carried out a retrospective hospital-based unmatched case-control study. A sample of 124 mother-newborn couples was interviewed in a private medical unit in Monterrey, Mexico, from January 2001 to January 2002. The association between EBF and 11 explanatory factors was analyzed by logistic regression analysis. Counseling and early contact between mother-newborn couples were positively associated with EBF. Counseling and early contact improve EBF practice. We believe these two practices would favor better adherence to EBF in other populations.

  2. Label-free potentiometric biosensor based on solid-contact for determination of total phenols in honey and propolis.

    Science.gov (United States)

    Draghi, Patrícia Ferrante; Fernandes, Julio Cesar Bastos

    2017-03-01

    We developed a label-free potentiometric biosensor using tyrosinase extracted from Musa acuminata and immobilized by covalent bond on a surface of a solid-contact transducer. The transducer was manufactured containing two layers. The first layer contained a blend of poly(vinyl) chloride carboxylated (PVC-COOH), graphite and potassium permanganate. On this layer, we deposited a second layer containing just a mixture of poly(vinyl chloride) carboxylated and graphite. On the last layer of the transducer, we immobilized the tyrosinase enzyme by reaction with N-(3-dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride. The solid-contact potentiometric biosensor presented at low detection limit of 7.3×10-7M and a linear range to catechol concentration between 9.3×10-7M and 8.3×10-2M. This biosensor was applied to determine the amount of total phenols in different samples of honey and propolis. The results agreed with the Folin-Ciocalteu method. Copyright © 2016 Elsevier B.V. All rights reserved.

  3. Development of a wearable CMOS-based contact imaging system for real-time skin condition diagnosis

    Science.gov (United States)

    Petitdidier, Nils; Koenig, Anne; Gerbelot, Rémi; Gioux, Sylvain; Dinten, Jean-Marc

    2017-07-01

    Diffuse reflectance spectroscopy has been widely used in the field of biological tissue characterization with various modalities [1-5,6]. One of these modalities consists in measuring the spatially resolved diffuse reflectance (SRDR). In this technique, light is collected at multiple distances from the excitation point. The obtained reflectance decay curve is used to determine scattering and absorption properties of the tissue [7], which are directly related to tissue content and structure. Existing systems usually use fiber optics to collect light reflected from the tissue and transfer it to an optical sensor [1,6]. Such devices make it possible to perform SRDR measurements directly in contact with the tissue. However, they offer poor spatial sampling of the reflectance and low light collection efficiency. We propose to overcome these limitations by using a CMOS sensor placed in contact with the tissue to achieve light collection with high spatial sampling over several millimeters and with increased fill factor. Our objective in this paper is to demonstrate the potential of our instrument to determine the optical properties of tissues from SRDR measurements. We first describe the instrument and the employed methodology. Then, preliminary results obtained on optical phantoms are presented. Finally, the potential of our system for SRDR measurements is evaluated through comparison with a fiber-optic probe previously developed in our laboratory [6,8].

  4. Why Patients Delay Their First Contact with Health Services After Stroke? A Qualitative Focus Group-Based Study.

    Directory of Open Access Journals (Sweden)

    Alice Le Bonniec

    Full Text Available Despite national and local French information campaigns, when acute stroke occurs, waiting times before calling mobile emergency medical services (EMS to receive appropriate treatment (i.e. thrombolysis and decrease the risk of physical disability, remain long. We aimed to identify the representations of stroke in the general population and to determine barriers to and facilitators for rapidly contacting EMS.We conducted a qualitative study among the general population with 10 focus groups, 5 comprising employed people (N = 29 and 5 comprising retirees (N = 32. The themes discussed were general knowledge about stroke and its risk factors, symptoms, appropriate management and the awareness that stroke is an emergency issue.In addition to a lack of knowledge about stroke, other barriers to rapidly contacting the EMS were difficulties in recognizing symptoms and understanding that these symptoms constitute an emergency. Furthermore, when faced with stroke, a feeling of inevitability and fatalism about the consequences of a stroke was highlighted. Participants were unaware of the existence of an effective treatment and they mistrusted medical competences. Finally, we found a strong presence and participant appreciation of common knowledge, resulting in the sharing of experiences of stroke. This could partly compensate for the lack of specific knowledge about symptom recognition and appropriate action.Information campaigns should not only inform the public about stroke symptoms in order to ensure people act appropriately, but should also focus on increasing public awareness about the fact that an effective treatment exists.

  5. Novel co-culture plate enables growth dynamic-based assessment of contact-independent microbial interactions.

    Science.gov (United States)

    Moutinho, Thomas J; Panagides, John C; Biggs, Matthew B; Medlock, Gregory L; Kolling, Glynis L; Papin, Jason A

    2017-01-01

    Interactions between microbes are central to the dynamics of microbial communities. Understanding these interactions is essential for the characterization of communities, yet challenging to accomplish in practice. There are limited available tools for characterizing diffusion-mediated, contact-independent microbial interactions. A practical and widely implemented technique in such characterization involves the simultaneous co-culture of distinct bacterial species and subsequent analysis of relative abundance in the total population. However, distinguishing between species can be logistically challenging. In this paper, we present a low-cost, vertical membrane, co-culture plate to quantify contact-independent interactions between distinct bacterial populations in co-culture via real-time optical density measurements. These measurements can be used to facilitate the analysis of the interaction between microbes that are physically separated by a semipermeable membrane yet able to exchange diffusible molecules. We show that diffusion across the membrane occurs at a sufficient rate to enable effective interaction between physically separate cultures. Two bacterial species commonly found in the cystic fibrotic lung, Pseudomonas aeruginosa and Burkholderia cenocepacia, were co-cultured to demonstrate how this plate may be implemented to study microbial interactions. We have demonstrated that this novel co-culture device is able to reliably generate real-time measurements of optical density data that can be used to characterize interactions between microbial species.

  6. Plastic deformation and contact area of an elastic-plastic contact of ellipsoid bodies after unloading

    NARCIS (Netherlands)

    Jamari, Jamari; Schipper, Dirk J.

    2007-01-01

    This paper presents theoretical and experimental results of the residual or plastic deformation and the plastic contact area of an elastic–plastic contact of ellipsoid bodies after unloading. There are three regime responses of the deformation and contact area: elastic, elastic–plastic and fully

  7. Application of Iterative Robust Model-based Optimal Experimental Design for the Calibration of Biocatalytic Models

    DEFF Research Database (Denmark)

    Van Daele, Timothy; Gernaey, Krist V.; Ringborg, Rolf Hoffmeyer

    2017-01-01

    The aim of model calibration is to estimate unique parameter values from available experimental data, here applied to a biocatalytic process. The traditional approach of first gathering data followed by performing a model calibration is inefficient, since the information gathered during...... experimentation is not actively used to optimise the experimental design. By applying an iterative robust model-based optimal experimental design, the limited amount of data collected is used to design additional informative experiments. The algorithm is used here to calibrate the initial reaction rate of an ω......-transaminase catalysed reaction in a more accurate way. The parameter confidence region estimated from the Fisher Information Matrix is compared with the likelihood confidence region, which is a more accurate, but also a computationally more expensive method. As a result, an important deviation between both approaches...

  8. Experimental research of the synthetic jet generator designs based on actuation of diaphragm with piezoelectric actuator

    Science.gov (United States)

    Rimasauskiene, R.; Matejka, M.; Ostachowicz, W.; Kurowski, M.; Malinowski, P.; Wandowski, T.; Rimasauskas, M.

    2015-01-01

    Experimental analyses of four own developed synthetic jet generator designs were presented in this paper. The main task of this work was to find the most appropriate design of the synthetic jet generator. Dynamic characteristics of the synthetic jet generator's diaphragm with piezoelectric material were measured using non-contact measuring equipment laser vibrometer Polytec®PSV 400. Temperatures of the piezoelectric diaphragms working in resonance frequency were measured with Fiber Bragg Grating (FBG) sensor. Experimental analysis of the synthetic jet generator amplitude-frequency characteristics were performed using CTA (hot wire anemometer) measuring techniques. Piezoelectric diaphragm in diameter of 27 mm was excited by sinusoidal voltage signal and it was fixed tightly inside the chamber of the synthetic jet generator. The number of the synthetic jet generator orifices (1 or 3) and volume of cavity (height of cavity vary from 0.5 mm to 1.5 mm) were changed. The highest value of the synthetic jet velocity 25 m/s was obtained with synthetic jet generator which has cavity 0.5 mm and 1 orifice (resonance frequency of the piezoelectric diaphragm 2.8 kHz). It can be concluded that this type of the design is preferred in order to get the peak velocity of the synthetic jet.

  9. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... with Colored Contact Lenses Julian: Teenager Blinded In One Eye By Non-Prescription Contact Lens Laura: Vision ... Robyn: Blurry Vision and Daily Eye Drops After One Use Facts About Colored Contacts and Halloween Safety ...

  10. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... People, Real Problems with Colored Contact Lenses Julian: Teenager Blinded In One Eye By Non-Prescription Contact ... colored contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses you are ...

  11. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Purchase the colored contact lenses from an eye product retailer who asks for a prescription. Follow the contact lens care directions for cleaning, disinfecting, and wearing the lenses. Never share contact ...

  12. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... use of colored contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses ...

  13. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... Costume Contact Lenses Can Ruin Vision Eye Makeup Safety In fact, it is illegal to sell colored ...

  14. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Vision and Daily Eye Drops After One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume Contacts May Contain Chemicals ...

  15. Contact pin-printing of albumin-fungicide conjugate for silicon nitride-based sensors biofunctionalization: Multi-technique surface analysis for optimum immunoassay performance

    Science.gov (United States)

    Gajos, Katarzyna; Budkowski, Andrzej; Tsialla, Zoi; Petrou, Panagiota; Awsiuk, Kamil; Dąbczyński, Paweł; Bernasik, Andrzej; Rysz, Jakub; Misiakos, Konstantinos; Raptis, Ioannis; Kakabakos, Sotirios

    2017-07-01

    Mass fabrication of integrated biosensors on silicon chips is facilitated by contact pin-printing, applied for biofunctionalization of individual Si3N4-based transducers at wafer-scale. To optimize the biofunctionalization for immunochemical (competitive) detection of fungicide thiabendazole (TBZ), Si3N4 surfaces are modified with (3-aminopropyl)triethoxysilane and examined after: immobilization of BSA-TBZ conjugate (probe) from solutions with different concentration, blocking with bovine serum albumin (BSA), and immunoreaction with a mouse monoclonal antibody against TBZ. Nanostructure, surface density, probe composition and coverage uniformity of protein layers are evaluated with Atomic Force Microscopy, Spectroscopic Ellipsometry, Time-of-Flight Secondary Ion Mass Spectrometry and X-ray Photoelectron Spectroscopy. Contact pin-printing of overlapping probe spots is compared with hand spotted areas. Contact pin-printing resulted in two-fold increase of immobilized probe surface density as compared to hand spotting. Regarding BSA-TBZ immobilization, an incomplete monolayer develops into a bilayer as the concentration of BSA-TBZ molecules in the printing solution increases from 25 to 100 μg/mL. Upon blocking, however, a complete protein monolayer is formed for all the BSA-TBZ concentrations used. Free surface sites are filled with BSA for low surface coverage with BSA-TBZ, whereas loosely bound BSA-TBZ molecules are removed from the BSA-TBZ bilayer. As a consequence immunoreaction efficiency increases with the printing probe concentration.

  16. Low-ohmic-contact-resistance V-based electrode for n-type AlGaN with high AlN molar fraction

    Science.gov (United States)

    Mori, Kazuki; Takeda, Kunihiro; Kusafuka, Toshiki; Iwaya, Motoaki; Takeuchi, Tetsuya; Kamiyama, Satoshi; Akasaki, Isamu; Amano, Hiroshi

    2016-05-01

    We investigated a V-based electrode for the realization of low ohmic-contact resistivity in n-type AlGaN with a high AlN molar fraction characterized by the circular transmission line model. The contact resistivity of n-type Al0.62Ga0.38N prepared using the V/Al/Ni/Au electrode reached 1.13 × 10-6 Ω cm2. Using this electrode, we also demonstrated the fabrication of UV light-emitting diodes (LEDs) with an emission wavelength of approximately 300 nm. An operating voltage of LED prepared using a V/Al/Ni/Au electrode was 1.6 V lower at 100 mA current injection than that prepared using a Ti/Al/Ti/Au electrode, with a specific contact resistance of approximately 2.36 × 10-4 Ω cm2 for n-type Al0.62Ga0.38N.

  17. Impact of DC-power during Mo back contact sputtering on the alkali distribution in Cu(In,Ga)Se{sub 2}-based thin film solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Lepetit, T., E-mail: thomas.lepetit@cnrs-imn.fr [Institut des Matériaux Jean Rouxel (IMN), UMR 6502 CNRS, 2 rue de la Houssinière BP 32229, 44322 Nantes Cedex 3 (France); Mangin, D. [Institut Jean Lamour, UMR 7198 CNRS — Université de Lorraine, Parc de Saurupt, CS 50840, 54011 Nancy Cedex (France); Gautron, E.; Tomassini, M.; Harel, S.; Arzel, L.; Barreau, N. [Institut des Matériaux Jean Rouxel (IMN), UMR 6502 CNRS, 2 rue de la Houssinière BP 32229, 44322 Nantes Cedex 3 (France)

    2015-05-01

    DC-sputtered Mo back contact layers were deposited on soda-lime glass (SLG) with different power densities applied on the Mo target to study its influence on the photovoltaic performance of Cu(In,Ga)Se{sub 2}-based (CIGSe) solar cell. CIGSe absorber was then deposited simultaneously on these SLG/Mo, following the 3-stage process. These devices have good but different photovoltaic performance (> 16% efficiency without MgF{sub 2} coating). To find a material origin, secondary ion mass spectroscopy (SIMS) profiles were carried out on complete cells, revealing that Na and K content and distribution in each layer depend on the deposition conditions of the back contact. Even before the CIGSe deposition and despite similar morphologies, Na content can vary 10-fold from one Mo layer to another. The same applies to the absorber; when grown on a different Mo they present the same grain boundary density but different alkali contents in bulk or at interfaces. This has an influence on the compositional grading in absorber, confirmed by X-ray diffraction and SIMS. - Highlights: • Mo films synthesized at different DC-power applied on the target during sputtering. • Similar macroscopic properties of Mo back contacts • The lowest alkali content in absorber with the highest DC-power applied during Mo sputtering.

  18. High-mobility, air stable bottom-contact n-channel thin film transistors based on N,N′-ditridecyl perylene diimide

    Energy Technology Data Exchange (ETDEWEB)

    Ma, Lanchao [Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Guo, Yunlong; Wen, Yugeng; Liu, Yunqi, E-mail: xwzhan@iccas.ac.cn, E-mail: liuyq@iccas.ac.cn [Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Zhan, Xiaowei, E-mail: xwzhan@iccas.ac.cn, E-mail: liuyq@iccas.ac.cn [Beijing National Laboratory for Molecular Sciences, CAS Key Laboratory of Organic Solids, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190 (China); Department of Materials Science and Engineering, College of Engineering, Peking University, Beijing 100871 (China)

    2013-11-11

    Bottom-gate bottom-contact (BGBC) organic thin film transistors (OTFTs) based on N,N′-ditridecyl perylene diimide exhibit electron mobility as high as 3.54 cm{sup 2} V{sup −1} s{sup −1} in nitrogen, higher than that (1 cm{sup 2} V{sup −1} s{sup −1}) of bottom-gate top-contact devices. The better performance of BGBC configuration in N{sub 2} is attributed to lower contact resistance, which is further reduced by thermal annealing. After thermally annealing the BGBC OTFTs at 180 °C, electron mobility as high as 3.5 cm{sup 2} V{sup −1} s{sup −1}, current on/off ratio of 10{sup 6} and threshold voltage of 9 V are achieved in air, and the mobility retains above 1 cm{sup 2} V{sup −1} s{sup −1} after storage for two months in air. Thermal treatment enhanced crystalline grains, reduced grain boundaries, and suppressed the adsorption of H{sub 2}O and O{sub 2}, leading to excellent performance in air.

  19. Contact Graph Routing

    Science.gov (United States)

    Burleigh, Scott C.

    2011-01-01

    Contact Graph Routing (CGR) is a dynamic routing system that computes routes through a time-varying topology of scheduled communication contacts in a network based on the DTN (Delay-Tolerant Networking) architecture. It is designed to enable dynamic selection of data transmission routes in a space network based on DTN. This dynamic responsiveness in route computation should be significantly more effective and less expensive than static routing, increasing total data return while at the same time reducing mission operations cost and risk. The basic strategy of CGR is to take advantage of the fact that, since flight mission communication operations are planned in detail, the communication routes between any pair of bundle agents in a population of nodes that have all been informed of one another's plans can be inferred from those plans rather than discovered via dialogue (which is impractical over long one-way-light-time space links). Messages that convey this planning information are used to construct contact graphs (time-varying models of network connectivity) from which CGR automatically computes efficient routes for bundles. Automatic route selection increases the flexibility and resilience of the space network, simplifying cross-support and reducing mission management costs. Note that there are no routing tables in Contact Graph Routing. The best route for a bundle destined for a given node may routinely be different from the best route for a different bundle destined for the same node, depending on bundle priority, bundle expiration time, and changes in the current lengths of transmission queues for neighboring nodes; routes must be computed individually for each bundle, from the Bundle Protocol agent's current network connectivity model for the bundle s destination node (the contact graph). Clearly this places a premium on optimizing the implementation of the route computation algorithm. The scalability of CGR to very large networks remains a research topic

  20. Effect of Computer-Based Video Games on Children: An Experimental Study

    Science.gov (United States)

    Chuang, Tsung-Yen; Chen, Wei-Fan

    2009-01-01

    This experimental study investigated whether computer-based video games facilitate children's cognitive learning. In comparison to traditional computer-assisted instruction (CAI), this study explored the impact of the varied types of instructional delivery strategies on children's learning achievement. One major research null hypothesis was…

  1. Can experimental data in humans verify the finite element-based bone remodeling algorithm?

    DEFF Research Database (Denmark)

    Wong, Christian; Gehrchen, P Martin; Kiaer, Thomas

    2008-01-01

    A finite element analysis-based bone remodeling study in human was conducted in the lumbar spine operated on with pedicle screws. Bone remodeling results were compared to prospective experimental bone mineral content data of patients operated on with pedicle screws....

  2. The impact of first eye cataract surgery on mental health contacts for depression and/or anxiety: a population-based study using linked data.

    Science.gov (United States)

    Meuleners, Lynn B; Hendrie, Delia; Fraser, Michelle L; Ng, Jonathon Q; Morlet, Nigel

    2013-09-01

    Cataract is the leading cause of reversible blindness worldwide, and the incidence of cataract surgery is projected to increase as the population ages. Gaining an understanding of the effects of cataract surgery on a range of health outcomes is important for maintaining the health and safety of older adults. A before and after cohort study was conducted using the Western Australian Hospital Morbidity Data System, Mental Health Information System and the Western Australian Death Registry. Of the 21 110 patients who underwent cataract surgery in one eye only, 295 had mental health contacts for depression and/or anxiety 1 year before (n = 158) or 1 year after (n = 137) surgery. Results from Poisson generalized estimating equations showed a significant decrease of 18.80% (p ≤ 0.001) in the number of mental health contacts for depression and/or anxiety the year after cataract surgery after accounting for potential confounding factors. A 27.46% increase in mental health contacts the year after cataract surgery was reported by women compared with men (95% CI: 1.08-1.50). Those living in remote areas had less contact with mental health services compared with those living in metropolitan areas (adjusted risk ratio 0.62, 95% CI: 0.46-0.84). The corresponding reduction in health care costs for treatment of depression and/or anxiety was 28%. Further research should be conducted to collect information on the utilization of health care resources not captured in this study, namely community-based services, visits to general practitioners and/or emergency departments as well as medication usage such as antidepressants. © 2013 Acta Ophthalmologica Scandinavica Foundation. Published by Blackwell Publishing Ltd.

  3. In vitro antimicrobial activity of an experimental dentifrice based on Ricinus communis.

    Science.gov (United States)

    Leite, Vanessa Maria Fagundes; Pinheiro, Juliana Barchelli; Pisani, Marina Xavier; Watanabe, Evandro; de Souza, Raphael Freitas; Paranhos, Helena de Freitas Oliveira; Lovato-Silva, Cláudia Helena

    2014-01-01

    This study evaluated the antimicrobial activity of a Ricinus communis-based experimental dentifrice for denture hygiene against the following standard strains: Staphylococcus aureus, Escherichia coli, Streptococcus mutans, Enterococcus faecalis, Candida albicans and Candida glabrata. The minimum inhibitory concentration (MIC) assay was performed with R. communis in pure oil at 2.5%. Only E. coli was not inhibited by R. communis, but the MIC (0.0781%) was effective against the other microorganisms. From these results it was determined the R. communis concentrations for experimental dentifrices, 1, 2, 5 and 10%, which were evaluated by the test-well diffusion in agar. The commercial dentifrices Colgate, Trihydral and Corega Brite were tested for comparative purposes. The diameter of the zones of bacterial growth inhibition produced around the wells was measured (in mm) with a rule under reflected light. Data were analyzed statistically by analysis of variance and Tukey's post-hoc test (α=0.05). Neither the commercial nor the experimental dentifrices were effective against E. coli. The experimental dentifrices containing R. communis at 2, 5 and 10% presented action against S. mutans, S. aureaus and E. faecallis. The experimental dentifrices showed no antimicrobial activity against Candida spp. and E. coli in any of the tested concentrations. Trihydral was the most effective. Comparing the experimental dentifrices, the product with 10% R. communis produced the largest zones of bacterial growth inhibition and had similar antimicrobial activity to the commercial dentifrices, except against S. aureus.

  4. A Comparative Study of the Gas Sensing Behavior in P3HT- and PBTTT-Based OTFTs: The Influence of Film Morphology and Contact Electrode Position

    Directory of Open Access Journals (Sweden)

    Kyriaki Manoli

    2014-09-01

    Full Text Available Bottom- and top-contact organic thin film transistors (OTFTs were fabricated, using poly(3-hexylthiophene-2,5-diyl (P3HT and poly[2,5-bis(3-tetradecylthiophen-2-ylthieno[3,2-b]thiophene] (PBTTT-C16 as p-type channel semiconductors. Four different types of OTFTs were fabricated and investigated as gas sensors against three volatile organic compounds, with different associated dipole moments. The OTFT-based sensor responses were evaluated with static and transient current measurements. A comparison between the different architectures and the relative organic semiconductor was made.

  5. Comparison of various structural damage tracking techniques based on experimental data

    Science.gov (United States)

    Huang, Hongwei; Yang, Jann N.; Zhou, Li

    2008-03-01

    Damage identification of structures is an important task of a health monitoring system. The ability to detect damages on-line or almost on-line will ensure the reliability and safety of structures. Analysis methodologies for structural damage identification based on measured vibration data have received considerable attention, including the least-square estimation (LSE), extended Kalman filter (EKF), etc. Recently, new analysis methods, referred to as the sequential non-linear least-square estimation (SNLSE) and quadratic sum-squares error (QSSE), have been proposed for the damage tracking of structures. In this paper, these newly proposed analysis methods will be compared with the LSE and EKF approaches, in terms of accuracy, convergence and efficiency, for damage identification of structures based on experimental data. A series of experimental tests using a small-scale 3-story building model have been conducted. In these experimental tests, white noise excitations were applied to the model, and different damage scenarios were simulated and tested. Here, the capability of the adaptive LSE, EKF, SNLSE and QSSE approaches in tracking the structural damage are demonstrated using experimental data. The tracking results for the stiffness of all stories, based on each approach, are compared with the stiffness predicted by the finite-element method. The advantages and drawbacks for each damage tracking approach will be evaluated in terms of the accuracy, efficiency and practicality.

  6. Pu239 Cross-Section Variations Based on Experimental Uncertainties and Covariances

    Energy Technology Data Exchange (ETDEWEB)

    Sigeti, David Edward [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Williams, Brian J. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Parsons, D. Kent [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-10-18

    Algorithms and software have been developed for producing variations in plutonium-239 neutron cross sections based on experimental uncertainties and covariances. The varied cross-section sets may be produced as random samples from the multi-variate normal distribution defined by an experimental mean vector and covariance matrix, or they may be produced as Latin-Hypercube/Orthogonal-Array samples (based on the same means and covariances) for use in parametrized studies. The variations obey two classes of constraints that are obligatory for cross-section sets and which put related constraints on the mean vector and covariance matrix that detemine the sampling. Because the experimental means and covariances do not obey some of these constraints to sufficient precision, imposing the constraints requires modifying the experimental mean vector and covariance matrix. Modification is done with an algorithm based on linear algebra that minimizes changes to the means and covariances while insuring that the operations that impose the different constraints do not conflict with each other.

  7. Design of a Lightweight, Cost Effective Thimble-Like Sensor for Haptic Applications Based on Contact Force Sensors

    Directory of Open Access Journals (Sweden)

    Ignacio Galiana

    2011-12-01

    Full Text Available This paper describes the design and calibration of a thimble that measures the forces applied by a user during manipulation of virtual and real objects. Haptic devices benefit from force measurement capabilities at their end-point. However, the heavy weight and cost of force sensors prevent their widespread incorporation in these applications. The design of a lightweight, user-adaptable, and cost-effective thimble with four contact force sensors is described in this paper. The sensors are calibrated before being placed in the thimble to provide normal and tangential forces. Normal forces are exerted directly by the fingertip and thus can be properly measured. Tangential forces are estimated by sensors strategically placed in the thimble sides. Two applications are provided in order to facilitate an evaluation of sensorized thimble performance. These applications focus on: (i force signal edge detection, which determines task segmentation of virtual object manipulation, and (ii the development of complex object manipulation models, wherein the mechanical features of a real object are obtained and these features are then reproduced for training by means of virtual object manipulation.

  8. Microdroplet-based On-Demand Drawing of High Aspect-Ratio Elastomeric Micropillar and Its Contact Sensing Application.

    Science.gov (United States)

    Li, Qiang; Dhakal, Rabin; Kim, Jaeyoun

    2017-12-05

    High aspect-ratio elastomeric micropillars play important roles as the platform for microscale sensing and actuation. Many soft-lithographic techniques have been developed for their facile realization but most of the techniques are limited to build the micropillars only on totally flat, widely accessible substrate areas with the micropillar's structural characteristics completely predetermined, leaving little room for in situ control. Here we demonstrate a new technique which overcomes these limitations by directly drawing micropillars from pipette-dispensed PDMS microdroplets using vacuum-chucked microspheres. The combined utilization of PDMS microdroplets and microspheres not only enables the realization of microsphere-tipped PDMS micropillars on non-flat, highly space-constrained substrate areas at in situ controllable heights but also allows arraying of micropillars with dissimilar heights at a close proximity. To validate the new technique's utility and versatility, we realize PDMS micropillars on various unconventional substrate areas in various configurations. We also convert one of them, the optical fiber/micropillar hybrid, into a soft optical contact sensor. Both the fabrication technique and the resulting sensing scheme will be useful for future biomedical microsystems.

  9. An MCMC-based waveform analysis with p-type point contact detectors in the MAJORANA DEMONSTRATOR

    Science.gov (United States)

    Shanks, Benjamin; MAJORANA Collaboration

    2017-01-01

    Statistical signal processing can be a powerful tool for extracting as much information as possible from raw data. By fitting data to a physical model of signal generation on an event-by-event basis, it can be used to perform precise event reconstruction and enable efficient background rejection. Searches for neutrinoless double-beta decay must achieve extremely low backgrounds to reach sensitivities required for discovery, and so can benefit greatly from this analysis technique. The MAJORANA DEMONSTRATOR has implemented a Markov Chain Monte Carlo (MCMC) signal processing algorithm to fit waveforms from p-type point contact (PPC) germanium detectors. After a machine learning step to tune detector fields and electronics response parameters, the MCMC algorithm is able to reconstruct the time, energy and position of interactions within the PPC detector. The parameters estimated with this method will find many applications within the DEMONSTRATOR physics program, including background identification and rejection. This will prove important as the DEMONSTRATOR aims to reach its background goal of < 3 counts/tonne/yr in the region of interest. This work is supported by the U.S. Department of Energy, Office of Science, Office of Nuclear Physics, the Particle Astrophysics and Nuclear Physics Programs of the National Science Foundation, and the Sanford Underground Research Facility.

  10. Zirconia-based dental crown to support a removable partial denture: a three-dimensional finite element analysis using contact elements and micro-CT data.

    Science.gov (United States)

    Rocha, Eduardo Passos; Anchieta, Rodolfo Bruniera; de Almeida, Erika Oliveira; Freitas, Amilcar Chagas; Martini, Ana Paula; Sotto-Maior, Bruno Sales; Luersen, Marco Antonio; Ko, Ching Chang

    2015-01-01

    Veneer fracture is the most common complication in zirconia-based restorations. The aim of this study was to evaluate the mechanical behavior of a zirconia-based crown in a lower canine tooth supporting removable partial denture (RPD) prosthesis, varying the bond quality of the veneer/coping interface. Microtomography (μCT) data of an extracted left lower canine were used to build the finite element model (M) varying the core material (gold core - MAu; zirconia core - MZi) and the quality of the veneer/core interface (complete bonded - MZi; incomplete bonded - MZi-NL). The incomplete bonding condition was only applied for zirconia coping by using contact elements (Target/Contact) with 0.3 frictional coefficients. Stress fields were obtained using Ansys Workbench 10.0. The loading condition (L = 1 N) was vertically applied at the base of the RPD prosthesis metallic support towards the dental apex. Maximum principal (σmax) and von Mises equivalent (σvM) stresses were obtained. The σmax (MPa) for the bonded condition was similar between gold and zirconia cores (MAu, 0.42; MZi, 0.40). The incomplete bonded condition (MZi-NL) raised σmax in the veneer up to 800% (3.23 MPa) in contrast to the bonded condition. The peak of σvM increased up to 270% in the MZi-NL. The incomplete bond condition increasing the stress in the veneer/zirconia interface.

  11. Experimental Study on MUSIC-Based DOA Estimation by Using Universal Steering Vector

    Science.gov (United States)

    Yuan, Qiaowei; Chen, Qiang; Sawaya, Kunio

    MUSIC-based estimation of direction of arrival (DOA) using universal steering vector (USV) is experimentally studied. A four-element array antenna and a four-channel receiver are employed for the experiment. In order to improve the accuracy of DOA estimation, USV which has already included the effect of mutual coupling between array elements and effect of array elements themselves is compensated to further include the electric delay and loss of four channels in the receiver. The compensated USV (C-USV) approach proposed in this paper does not need the time-consuming measurement of array element pattern because the compensating matrix for USV is obtained by measuring the S parameters between RF input ports of the feeding cables and IF output ports of the receiver. The experimental results of MUSIC-based DOA estimation show that C-USV approach is an accurate, effective and practical method for the MUSIC-based DOA estimation.

  12. Investigating the impact of SEM chamber conditions and imaging parameters on contact resistance of in situ nanoprobing

    Science.gov (United States)

    Qu, Juntian; Lee, Martin; Hilke, Michael; Liu, Xinyu

    2017-08-01

    In this paper, we investigate the impact of vacuum chamber conditions (cleanliness level and vacuum pressure) and imaging parameters (magnification and acceleration voltage) of scanning electron microscopy (SEM) on the contact resistance of two-point in situ nanoprobing of nanomaterials. Using two typical types of conductive nanoprobe, two-point nanoprobing is performed on silicon nanowires, during which changing trends of the nanoprobing contact resistance with the SEM chamber conditions and imaging parameters are quantified. The mechanisms underlying the experimental observations are also explained. Through systematically adjusting the experimental parameters, the probe-sample contact resistance is significantly reduced from the mega-ohm level to the kilo-ohm level. The experimental results can serve as a guideline to evaluate electrical contacts of nanoprobing and instruct how to reduce the contact resistance in SEM-based, two-point nanoprobing.

  13. The design of contact lens based ocular drug delivery systems for single-day use: Part (I) Structural factors, surrogate ophthalmic dyes and passive diffusion studies.

    Science.gov (United States)

    Mahomed, Anisa; Tighe, Brian J

    2014-09-01

    The poor retention and efficacy of instilled drops as a means of delivering drugs to the ophthalmic environment is well-recognised. The potential value of contact lenses as a means of ophthalmic drug delivery, and consequent improvement of pre-corneal retention is one obvious route to the development of a more effective ocular delivery system. Furthermore, the increasing availability and clinical use of daily disposable contact lenses provides the platform for the development of viable single-day use drug delivery devices based on existing materials and lenses. In order to provide a basis for the effective design of such devices, a systematic understanding of the factors affecting the interaction of individual drugs with the lens matrix is required. Because a large number of potential structural variables are involved, it is necessary to achieve some rationalisation of the parameters and physicochemical properties (such as molecular weight, charge, partition coefficients) that influence drug interactions. Ophthalmic dyes and structurally related compounds based on the same core structure were used to investigate these various factors and the way in which they can be used in concert to design effective release systems for structurally different drugs. Initial studies of passive diffusional release form a necessary precursor to the investigation of the features of the ocular environment that over-ride this simple behaviour. Commercially available contact lenses of differing structural classifications were used to study factors affecting the uptake of the surrogate actives and their release under 'passive' conditions. The interaction between active and lens material shows considerable and complex structure dependence, which is not simply related to equilibrium water content. The structure of the polymer matrix itself was found to have the dominant controlling influence on active uptake; hydrophobic interaction with the ophthalmic dye playing a major role. © The

  14. Contact lenses following keratoplasty.

    Science.gov (United States)

    Beekhuis, W H; van Rij, G; Eggink, F A; Vreugdenhil, W; Schoevaart, C E

    1991-01-01

    Bandage contact lenses can be used following keratoplasty to protect the ocular surface and promote epithelial healing. Rigid gas permeable contact lenses are indicated to correct irregular astigmatism and anisometropia. The Rotterdam Eye Hospital fit 77 keratoplasty patients with contact lenses following their surgery. The methods of fitting contact lenses over the irregular or highly astigmatic surface of a graft are discussed.

  15. Intuitive web-based experimental design for high-throughput biomedical data.

    Science.gov (United States)

    Friedrich, Andreas; Kenar, Erhan; Kohlbacher, Oliver; Nahnsen, Sven

    2015-01-01

    Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to keep track of the experimental design, including the conditions that are studied as well as information that might be interesting for failure analysis or further experiments in the future. In addition to the management of this information, means for an integrated design and interfaces for structured data annotation are urgently needed by researchers. Here, we propose a factor-based experimental design approach that enables scientists to easily create large-scale experiments with the help of a web-based system. We present a novel implementation of a web-based interface allowing the collection of arbitrary metadata. To exchange and edit information we provide a spreadsheet-based, humanly readable format. Subsequently, sample sheets with identifiers and metainformation for data generation facilities can be created. Data files created after measurement of the samples can be uploaded to a datastore, where they are automatically linked to the previously created experimental design model.

  16. Intuitive Web-Based Experimental Design for High-Throughput Biomedical Data

    Directory of Open Access Journals (Sweden)

    Andreas Friedrich

    2015-01-01

    Full Text Available Big data bioinformatics aims at drawing biological conclusions from huge and complex biological datasets. Added value from the analysis of big data, however, is only possible if the data is accompanied by accurate metadata annotation. Particularly in high-throughput experiments intelligent approaches are needed to keep track of the experimental design, including the conditions that are studied as well as information that might be interesting for failure analysis or further experiments in the future. In addition to the management of this information, means for an integrated design and interfaces for structured data annotation are urgently needed by researchers. Here, we propose a factor-based experimental design approach that enables scientists to easily create large-scale experiments with the help of a web-based system. We present a novel implementation of a web-based interface allowing the collection of arbitrary metadata. To exchange and edit information we provide a spreadsheet-based, humanly readable format. Subsequently, sample sheets with identifiers and metainformation for data generation facilities can be created. Data files created after measurement of the samples can be uploaded to a datastore, where they are automatically linked to the previously created experimental design model.

  17. Reaction time effects in lab- versus Web-based research: Experimental evidence.

    Science.gov (United States)

    Hilbig, Benjamin E

    2016-12-01

    Although Web-based research is now commonplace, it continues to spur skepticism from reviewers and editors, especially whenever reaction times are of primary interest. Such persistent preconceptions are based on arguments referring to increased variation, the limits of certain software and technologies, and a noteworthy lack of comparisons (between Web and lab) in fully randomized experiments. To provide a critical test, participants were randomly assigned to complete a lexical decision task either (a) in the lab using standard experimental software (E-Prime), (b) in the lab using a browser-based version (written in HTML and JavaScript), or (c) via the Web using the same browser-based version. The classical word frequency effect was typical in size and corresponded to a very large effect in all three conditions. There was no indication that the Web- or browser-based data collection was in any way inferior. In fact, if anything, a larger effect was obtained in the browser-based conditions than in the condition relying on standard experimental software. No differences between Web and lab (within the browser-based conditions) could be observed, thus disconfirming any substantial influence of increased technical or situational variation. In summary, the present experiment contradicts the still common preconception that reaction time effects of only a few hundred milliseconds cannot be detected in Web experiments.

  18. [Correct contact lens hygiene].

    Science.gov (United States)

    Blümle, S; Kaercher, T; Khaireddin, R

    2013-06-01

    Although contact lenses have long been established in ophthalmology, practical aspects of handling contact lenses is becoming increasingly less important in the clinical training as specialist for ophthalmology. Simultaneously, for many reasons injuries due to wearing contact lenses are increasing. In order to correct this discrepancy, information on contact lenses and practical experience with them must be substantially increased from a medical perspective. This review article deals with the most important aspects for prevention of complications, i.e. contact lens hygiene.

  19. Comportamiento de una pista experimental de pavimento flexible con base estabilizada con cal Behavior of an experimental track of flexible pavement with lime stabilized base

    Directory of Open Access Journals (Sweden)

    César Augusto Hidalgo Montoya

    2010-01-01

    Full Text Available En este trabajo se presentan resultados de una investigación realizada para determinar las propiedades de deformabilidad de bases estabilizadas con cal a partir de ensayos de campo no destructivos. Se realizaron ensayos de placa estática y viga Benkelman en un tramo de prueba de pavimento flexible de 70m de longitud. Se usaron diferentes mezclas de suelo-cal y varios espesores de la estructura para evaluar el comportamiento del pavimento. A partir de los resultados de estos ensayos fueron realizados retroanálisis del comportamiento del pavimento. El método de los elementos finitos y el modelo elástico de esfuerzos y deformaciones en sistema de capas múltiples se usaron en los retroanálisis para estimar los módulos de deformabilidad de la base estabilizada con cal. Se concluye que la adición de cal mejora sustancialmente las propiedades de los pavimentos evaluados.This paper presents results of a research carried out to determine the proprieties of deformation of lime stabilized bases using non destructive field tests. Static plate tests and Benkelman beam tests were made on an experimental track of flexible pavement of 70 m length. Several mixtures of soil-lime and several thickness of the stabilized base were used to evaluate the behavior of the pavement. With the results of these tests, back analysis of the behavior of pavement was carried out. The finite elements method and the elastic stress and strain in a multi layers system were used to estimate the deformation modulus of the lime stabilized bases. It is concluded that the lime addition significantly improves the properties of evaluated pavements.

  20. Ultraviolet/violet dual-color electroluminescence based on n-ZnO single crystal/p-GaN direct-contact light-emitting diode

    Energy Technology Data Exchange (ETDEWEB)

    Li, Songzhan [Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan, Hubei 430072 (China); School of Electronic and Electrical Engineering, Wuhan Textile University, Wuhan, Hubei 430073 (China); Lin, Wenwen [Laboratory of Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); Fang, Guojia, E-mail: gjfang@whu.edu.cn [Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan, Hubei 430072 (China); Huang, Feng, E-mail: fhuang@fjirsm.ac.cn [Laboratory of Materials Chemistry and Physics, Fujian Institute of Research on the Structure of Matter, Chinese Academy of Sciences, Fuzhou, Fujian 350002 (China); Huang, Huihui; Long, Hao; Mo, Xiaoming; Wang, Haoning; Guan, Wenjie; Zhao, Xingzhong [Key Laboratory of Artificial Micro- and Nano-structures of Ministry of Education, Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan, Hubei 430072 (China)

    2013-08-15

    We have fabricated a fully transparent ultraviolet (UV)/violet dual-color electroluminescence (EL) device based on n-ZnO single crystal and p-GaN via a simple direct-contact method. The device presents dual-color EL under forward and reverse biases—an intense violet emission centered at 400 nm from ZnO and a sharp UV emission peaked at 365 nm from GaN, respectively. The reason for dual color emissions is proposed in terms of the energy band theory and the transmission spectra of ZnO single crystal and p-GaN. -- Highlights: ► A fully transparent LED based on n-ZnO SC and p-GaN is fabricated via the direct-contact method. ► The n-ZnO SC/p-GaN device shows UV/violet dual-color emission under electrically pumped. ► The device presents a violet emission 400 nm and a UV emission 365 nm under forward and reverse biases. ► The EL of the dual-color device displays good stability and reproducibility.

  1. MEMS-based contact stress field measurements at a rough elastomeric layer: local test of Amontons’ friction law in static and steady sliding regimes

    Directory of Open Access Journals (Sweden)

    Debrégeas G.

    2010-06-01

    Full Text Available We present the results of recent friction experiments in which a MEMS-based sensing device is used to measure both the normal and tangential stress fields at the base of a rough elastomer film in frictional contact with smooth, rigid, glass indentors. We consider successively multicontacts under (i static normal loading by a spherical indentor and (ii frictional steady sliding conditions against a cylindrical indentor, for an increasing normal load. In both cases, the measured fields are compared to elastic calculations assuming (i a smooth interface and (ii Amontons’ friction law. In the static case, significant deviations are observed which decrease with increasing load and which vanish when a lubricant is used. In the steady sliding case, Amontons’ law reproduces rather satisfactorily the experiments provided that the normal/tangential coupling at the contact interface is taken into account. We discuss the origin of the difference between the Amontons fields and the measured ones, in particular the effect of the finite normal and tangential compliances of the multicontact interface.

  2. Morphological study of polymer surfaces exposed to non-thermal plasma based on contact angle and the use of scaling laws

    Energy Technology Data Exchange (ETDEWEB)

    Felix, T., E-mail: tsfelix81@gmail.com [Chemistry Department, Federal University of Santa Catarina, Campus Trindade, 88040-900 Florianópolis, SC (Brazil); Cassini, F.A.; Benetoli, L.O.B. [Chemistry Department, Federal University of Santa Catarina, Campus Trindade, 88040-900 Florianópolis, SC (Brazil); Dotto, M.E.R. [Physics Department, Federal University of Santa Catarina, Campus Trindade, 88040-900 Florianópolis, SC (Brazil); Debacher, N.A. [Chemistry Department, Federal University of Santa Catarina, Campus Trindade, 88040-900 Florianópolis, SC (Brazil)

    2017-05-01

    Highlights: • Polymeric surfaces were etched using non-thermal plasma at different intensities. • Polymers of low mechanical hardness reached the saturation level faster. • A mathematical model based on scaling laws was proposed. - Abstract: The experiments presented in this communication have the purpose to elaborate an explanation for the morphological evolution of the growth of polymeric surfaces provided by the treatment of non-thermal plasma. According to the roughness analysis and the model proposed by scaling laws it is possible relate to a predictable or merely random effect. Polyethylene terephthalate (PET) and poly(etherether)ketone (PEEK) samples were exposed to a non-thermal plasma discharge and the resulting surfaces roughness were analyzed based on the measurements from contact angle, scanning electron microscopy and atomic force microscopy coupled with scaling laws analysis which can help to describe and understand the dynamic of formation of a wide variety of rough surfaces. The roughness, R{sub RMS} (RMS- Root Mean Square) values for polymer surface range between 19.8 nm and 110.9 nm. The contact angle and the AFM (Atomic Force Microscopy) measurements as a function of the plasma exposure time were in agreement with both polar and dispersive components according to the surface roughness and also with the morphology evaluated described by Wolf-Villain model, with proximate values of α between 0.91{sub (PET)} and 0.88{sub (PEEK)}, β = 0.25{sub (PET)} and z = 3,64{sub (PET)}.

  3. Integration of experimental facilities: A joint effort for establishing a common knowledge base in experimental work on hydrogen safety

    NARCIS (Netherlands)

    Reinecke, E.A.; Huebert, T.; Tkatschenko, I.; Kessler, A.; Kuznetsov, M.; Wilkins, M.; Hedley, D.; Azkarate, I.; Proust, C.; Acosta-Iborra, B.; Gavrikov, B.; Bruijn, P.C.J. de; Marangon, A.; Teodorczyk, A.; Grafwallner, A.

    2011-01-01

    In the area of hydrogen safety, research facilities are essential for the experimental investigation of relevant phenomena, for testing devices and safety concepts, as well as for the generation of validation data for the various numerical codes and models. Within the framework of the European

  4. Experimental Study on LTCC Glass-Ceramic Based Dual Segment Cylindrical Dielectric Resonator Antenna

    Directory of Open Access Journals (Sweden)

    Ravi Kumar Gangwar

    2013-01-01

    Full Text Available The measured characteristics in C/X bands, including material properties of a dual segment cylindrical dielectric resonator antenna (CDRA fabricated from glass-ceramic material based on B2O3–La2O3–MgO glass and La(Mg0.5Ti0.5O3 ceramic, are reported. The sintering characteristic of the ceramic in presence of glass is determined from contact angle measurement and DTA. The return loss and input impedance versus frequency characteristics and radiation patterns of CDRA at its resonant frequency of 6.31 GHz are studied. The measured results for resonant frequency and return loss bandwidth of the CDRA are also compared with corresponding theoretical ones.

  5. Experimental Validation of the Sensitivity of Waveguide Grating Based Refractometric (Bio)sensors

    Science.gov (United States)

    Gartmann, Thomas E.; Kehl, Florian

    2015-01-01

    Despite the fact that the theoretical foundations of the sensitivity of waveguide grating based (bio)sensors are well-known, understood and their implications anticipated by the scientific community since several decades, to our knowledge, no prior publication has experimentally confirmed waveguide sensitivity for multiple film thicknesses, wavelengths and polarization of the propagating light. In this paper, the bulk refractive index sensitivity versus waveguide thickness of said refractometric sensors is experimentally determined and compared with predictions based on established theory. The effective refractive indices and the corresponding sensitivity were determined via the sensors’ coupling angles at different cover refractive indices for transverse electric as well as transverse magnetic polarized illumination at various wavelengths in the visible and near-infrared. The theoretical sensitivity was calculated by solving the mode equation for a three layer waveguide. PMID:25871832

  6. Growth control of the cranial base. A study with experimentally bipedal male rats

    Energy Technology Data Exchange (ETDEWEB)

    Smit-Vis, J.H.

    1981-01-01

    In a cross-sectional study the postnatal development of the skull, particularly that of the cranial base, was studied in experimentally bipedal male rats, up to the age of 46 weeks. A total of 81 bipedal rats and a control group of 90 animals were studied. It was found that, as compared with control rats, the bipedal rats had a definitely more spherical skull. This was the result of an increased height and a stronger dorsal flexion of the anterior cranial base. As to the chondrocranial elements, the basi-occipital bone reached, on the average, the same length in bipedal rats as in controls. However, the basisphenoid bone was significantly shorter. Arguments are given to relate the latter phenomenon to the altered shape of the neurocranium. The conclusion is drawn that, in this experimental approach, chondrocranial growth at the intersphenoidal synchondrosis is controlled not only by intrinsic genetic factors but also by local epigenetic and/or environmental factors.

  7. Educational Game Design. Bridging the gab between computer based learning and experimental learning environments

    DEFF Research Database (Denmark)

    Andersen, Kristine

    2007-01-01

    Considering the rapidly growing amount of digital educational materials only few of them bridge the gab between experimental learning environments and computer based learning environments (Gardner, 1991). Observations from two cases in primary school and lower secondary school in the subject...... of home economics shows that problems in computer based learning occurs when the basis of the learning process changes from being hands-on experimental with the subject to being experienced through or with a computer. Some of the central problems in home economics are to force abstraction from...... with a prototype of a MOO storyline. The aim of the MOO storyline is to challenge the potential of dialogue, user involvement, and learning responsibility and to use the children?s natural curiosity and motivation for game playing, especially when digital games involves other children. The paper proposes a model...

  8. Basic Research on a Latent Heat Thermal Energy Storage by Direct Contact Melting and Soldification

    Science.gov (United States)

    Saito, Akihiro; Saito, Akio; Utaka, Yoshio; Okuda, Kenichi; Katayama, Kozo

    A basic experimental research on a latent heat thermal energy storage system , utilizing a simple and effective heat exchange mechanism by a direct contact between the phase change material (PCM) and the heat transfer fluid (HTF), was shown. Discharging experiments on direct contact latent heat thermal energy reservoir using n-Eicosane as the PCM and water as the HTF, were performed, based on the conditions obtained in previous report. Then, operating conditions for suitable discharging process were searched from the experimental results (outlet water temperature response and local temperature response in the reservoir). Moreover, solidification mechanisms of PCM, which had been presumed in previous report, were confirmed from these experimental results, and the simple physical model on direct contact heat exchange in the reservoir was proposed. Then, the outlet water temperature response by this model was compared with the experimental results.

  9. 30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

    CERN Multimedia

    Jean-Claude Gadmer

    2013-01-01

    30 August 2013 - Senior Vice Minister for Foreign Affairs in Japan M. Matsuyama signing the guest book with CERN Director-General; visit the ATLAS experimental cavern with ATLAS Spokesperson D. Charlton and visiting the LHC tunnel at Point 1 with former ATLAS Japan national contact physicist T. Kondo. R. Voss and K. Yoshida present throughout.

  10. Experimental Study on Damage Detection in Timber Specimens Based on an Electromechanical Impedance Technique and RMSD-Based Mahalanobis Distance

    Directory of Open Access Journals (Sweden)

    Dansheng Wang

    2016-10-01

    Full Text Available In the electromechanical impedance (EMI method, the PZT patch performs the functions of both sensor and exciter. Due to the high frequency actuation and non-model based characteristics, the EMI method can be utilized to detect incipient structural damage. In recent years EMI techniques have been widely applied to monitor the health status of concrete and steel materials, however, studies on application to timber are limited. This paper will explore the feasibility of using the EMI technique for damage detection in timber specimens. In addition, the conventional damage index, namely root mean square deviation (RMSD is employed to evaluate the level of damage. On that basis, a new damage index, Mahalanobis distance based on RMSD, is proposed to evaluate the damage severity of timber specimens. Experimental studies are implemented to detect notch and hole damage in the timber specimens. Experimental results verify the availability and robustness of the proposed damage index and its superiority over the RMSD indexes.

  11. An Experimental ASON Based on OADM Rings and a GMPLS Control Plane

    Science.gov (United States)

    Munoz, R.; Pinart, C.; Martinez, R.; Junyent, A.; Junyent, G.

    This article presents the architecture of an ASON testbed implemented in the EMPIRICO project, focusing on design and implementation issues of real-time provisioning of bidirectional optical connections supported by a distributed GMPLS-based control plane and triggered by the network management system. Experimental performance is evaluated over a unidirectional and a bidirectional all-optical OADM ring in which neither wavelength converters nor optical resources discovery are employed. Performance analysis evaluates the blocking probability and the connection setup time.

  12. Definition and detection of contact in atomistic simulations

    NARCIS (Netherlands)

    Solhjoo, Soheil; Vakis, Antonis I.

    2015-01-01

    In atomistic simulations, contact depends on the accurate detection of contacting atoms as well as their contact area. While it is common to define contact between atoms based on the so-called ‘contact distance’ where the interatomic potential energy reaches its minimum, this discounts, for example,

  13. Temperature dependences of the contact resistivity in ohmic contacts to n{sup +}-InN

    Energy Technology Data Exchange (ETDEWEB)

    Sachenko, A. V.; Belyaev, A. E. [National Academy of Sciences, Lashkaryov Institute of Semiconductor Physics (Ukraine); Boltovets, N. S. [“Orion” Research Institute (Ukraine); Brunkov, P. N.; Jmerik, V. N.; Ivanov, S. V. [Russian Academy of Sciences, Ioffe Physical-Technical Institute (Russian Federation); Kapitanchuk, L. M. [National Academy of Sciences of Ukraine, Paton Electric Welding Institute (Ukraine); Konakova, R. V., E-mail: konakova@isp.kiev.ua; Klad’ko, V. P.; Romanets, P. N.; Saja, P. O.; Safryuk, N. V.; Sheremet, V. N. [National Academy of Sciences, Lashkaryov Institute of Semiconductor Physics (Ukraine)

    2015-04-15

    The temperature dependences of the contact resistivity (ρ{sub c}) of ohmic contacts based on the Au-Ti-Pd-InN system are measured at an InN doping level of 2 × 10{sup 18} cm{sup −3} in the temperature range of 4.2–300 K. At temperatures T > 150 K, linearly increasing dependences ρ{sub c}(T) are obtained. The dependences are explained within the mechanism of thermionic current flow through metal shunts associated with dislocations. Good agreement between theoretical and experimental dependences is achieved assuming that the flowing current is limited by the total resistance of the metal shunts, and the density of conductive dislocations is ∼5 × 10{sup 9} cm{sup −2}. Using the X-ray diffraction method, the density of screw and edge dislocations in the structure under study is measured: their total density exceeds 10{sup 10} cm{sup −2}.

  14. Electromagnetic Vortex-Based Radar Imaging Using a Single Receiving Antenna: Theory and Experimental Results

    Directory of Open Access Journals (Sweden)

    Tiezhu Yuan

    2017-03-01

    Full Text Available Radar imaging based on electromagnetic vortex can achieve azimuth resolution without relative motion. The present paper investigates this imaging technique with the use of a single receiving antenna through theoretical analysis and experimental results. Compared with the use of multiple receiving antennas, the echoes from a single receiver cannot be used directly for image reconstruction using Fourier method. The reason is revealed by using the point spread function. An additional phase is compensated for each mode before imaging process based on the array parameters and the elevation of the targets. A proof-of-concept imaging system based on a circular phased array is created, and imaging experiments of corner-reflector targets are performed in an anechoic chamber. The azimuthal image is reconstructed by the use of Fourier transform and spectral estimation methods. The azimuth resolution of the two methods is analyzed and compared through experimental data. The experimental results verify the principle of azimuth resolution and the proposed phase compensation method.

  15. Effects of the F4TCNQ-Doped Pentacene Interlayers on Performance Improvement of Top-Contact Pentacene-Based Organic Thin-Film Transistors

    Directory of Open Access Journals (Sweden)

    Ching-Lin Fan

    2016-01-01

    Full Text Available In this paper, the top-contact (TC pentacene-based organic thin-film transistor (OTFT with a tetrafluorotetracyanoquinodimethane (F4TCNQ-doped pentacene interlayer between the source/drain electrodes and the pentacene channel layer were fabricated using the co-evaporation method. Compared with a pentacene-based OTFT without an interlayer, OTFTs with an F4TCNQ:pentacene ratio of 1:1 showed considerably improved electrical characteristics. In addition, the dependence of the OTFT performance on the thickness of the F4TCNQ-doped pentacene interlayer is weaker than that on a Teflon interlayer. Therefore, a molecular doping-type F4TCNQ-doped pentacene interlayer is a suitable carrier injection layer that can improve the TC-OTFT performance and facilitate obtaining a stable process window.

  16. Large deformation and adhesive contact studies of axisymmetric membranes.

    Science.gov (United States)

    Laprade, Evan J; Long, Rong; Pham, Jonathan T; Lawrence, Jimmy; Emrick, Todd; Crosby, Alfred J; Hui, Chung-Yuen; Shull, Kenneth R

    2013-02-05

    A model membrane contact system consisting of an acrylic copolymer membrane and a PDMS substrate was utilized to evaluate a recently developed nonlinear large-deformation adhesive contact analysis. Direct measurements of the local membrane apex strain during noncontact inflation indicated that the neo-Hookean model provides an accurate measure of membrane strain and supports its use as the strain energy function for the analysis. Two membrane contact geometries, exhibiting significantly different strain distributions during withdrawal, were investigated. The first examines the wet contact of an air pressurized membrane. The second looks at the dry contact of a fluid deformed membrane in which a stepper motor controls membrane-substrate separation. A time-dependent modulus emerges from the analysis, with principal tensions obtained from a comparison of predicted and experimental membrane profiles. The applicability of this numerical analysis for determining membrane tension, however, is limited by wrinkling instabilities and viscoelasticity. For this reason, a conceptually simpler method, based on the direct measurement of the membrane tension and contact angle, was also utilized. The traditional peel energy defined with this direct measurement accurately described the membrane/substrate adhesive interactions, giving well-defined peel energies that were independent of the detailed strain state of the membrane.

  17. Nonlinear Contact Effects in Staggered Thin-Film Transistors

    Science.gov (United States)

    Fischer, Axel; Zündorf, Hilke; Kaschura, Felix; Widmer, Johannes; Leo, Karl; Kraft, Ulrike; Klauk, Hagen

    2017-11-01

    The static and dynamic electrical characteristics of thin-film transistors (TFTs) are often limited by the parasitic contact resistances, especially for TFTs with a small channel length. For the smallest possible contact resistance, the staggered device architecture has a general advantage over the coplanar architecture of a larger injection area. Since the charge transport occurs over an extended area, it is inherently more difficult to develop an accurate analytical device model for staggered TFTs. Most analytical models for staggered TFTs, therefore, assume that the contact resistance is linear, even though this is commonly accepted not to be the case. Here, we introduce a semiphenomenological approach to accurately fit experimental data based on a highly discretized equivalent network circuit explicitly taking into account the inherent nonlinearity of the contact resistance. The model allows us to investigate the influence of nonlinear contact resistances on the static and dynamic performance of staggered TFTs for different contact layouts with a relatively short computation time. The precise extraction of device parameters enables us to calculate the transistor behavior as well as the potential for optimization in real circuits.

  18. [Application of key contact point management in health education at ICU for oral and maxillofacial cancer patients].

    Science.gov (United States)

    Yang, Yue-Lai; Huang, Yao; Xu, Zhi-Xia; Mao, Yue-Li; Wang, Hui-Fen

    2017-02-01

    To explore the effect of key contact point management in health education at ICU for oral and maxillofacial cancer patients. Key contact point checklist was constructed by literature review, brain storm, patients review and expert consultation. The patients in the control group accepted routine health education, while patients in the experimental group accepted health education based on key contact point theory. The data were analyzed by nonparametric rank sum test using SPSS 17.0 software package. The key contact point checklist for oral and maxillofacial cancer patients consisted of 11 items. After intervention, the understanding rate and the satisfaction rate of patients in the experimental group were improved significantly than those in the control group. Health education model based on key contact point theory can effectively improve the quality of health education and patients' satisfaction.

  19. Infectious Gastroenteritis and the Need for Strict Contact Precaution Procedures in Adults Presenting in the Emergency Department - a Danish Register-based Study

    DEFF Research Database (Denmark)

    Skyum, Florence; Andersen, Vibeke; Chen, Ming

    2018-01-01

    or Clostridium difficile cases, who should remain on strict contact precautions. CONCLUSION: The initiation of contact precaution has to be assessed for 4.3% of all emergency department patients; 19% of the patients who had a sample tested had highly contagious gastroenteritis and required strict contact...

  20. Physically-Based Interactive Flow Visualization Based on Schlieren and Interferometry Experimental Techniques

    KAUST Repository

    Brownlee, C.

    2011-11-01

    Understanding fluid flow is a difficult problem and of increasing importance as computational fluid dynamics (CFD) produces an abundance of simulation data. Experimental flow analysis has employed techniques such as shadowgraph, interferometry, and schlieren imaging for centuries, which allow empirical observation of inhomogeneous flows. Shadowgraphs provide an intuitive way of looking at small changes in flow dynamics through caustic effects while schlieren cutoffs introduce an intensity gradation for observing large scale directional changes in the flow. Interferometry tracks changes in phase-shift resulting in bands appearing. The combination of these shading effects provides an informative global analysis of overall fluid flow. Computational solutions for these methods have proven too complex until recently due to the fundamental physical interaction of light refracting through the flow field. In this paper, we introduce a novel method to simulate the refraction of light to generate synthetic shadowgraph, schlieren and interferometry images of time-varying scalar fields derived from computational fluid dynamics data. Our method computes physically accurate schlieren and shadowgraph images at interactive rates by utilizing a combination of GPGPU programming, acceleration methods, and data-dependent probabilistic schlieren cutoffs. Applications of our method to multifield data and custom application-dependent color filter creation are explored. Results comparing this method to previous schlieren approximations are finally presented. © 2011 IEEE.

  1. Transfer of contaminants from surface to hands : experimental assessment of linearity of the exposure process, adherence to the skin, and area exposed during fixed pressure and repeated contact with surfaces contaminated with a powder

    NARCIS (Netherlands)

    Brouwer, D.H.; Kroese, R.; Hemmen, J.J. van

    1999-01-01

    Estimation of dermal exposure in the workplace resulting from contact with contaminated surfaces is important in risk assessment. Models have been developed to describe the process of exposure due to transfer, but for major input parameters - that is, contact area surface and adherence - defaults

  2. Cytotoxicity and genotoxicity of natural resin-based experimental endodontic sealers.

    Science.gov (United States)

    Silva, Gleyce O; Cavalcanti, Bruno N; Oliveira, Tatiana R; Bin, Claudia V; Camargo, Samira E A; Camargo, Carlos H R

    2016-05-01

    The development of endodontic sealers based on natural resins seems to be promising, given their improved biological properties. This study evaluated the cytotoxic and genotoxic effects of two experimental root canal sealers, based on extracts from Copaifera multijuga and Ricinus communis (castor oil polymer), comparing them to synthetic resin-based sealers: a single methacrylate-based, a multi-methacrylate-based, and an epoxy resin-based sealers. Sealers were prepared, set, and exposed to cell culture medium for 24 h at 37 °C with CO2. V79 cells were exposed to serial dilutions of the extracts of each sealer for 24 h. Cell viability was measured by the MTT assay and genotoxicity was assessed by the formation of micronuclei. The single methacrylate-based sealer had the most cytotoxic effects, with significant reduction in cell viability in all dilutions of the extract. The castor oil polymer-based sealer was, on the other hand, the most biocompatible sealer, with no cytotoxic effects at any concentration. All tested sealers were not genotoxic, excepting the single methacrylate-based sealer. The tested natural resin-based sealers presented low cytotoxic and no genotoxic effects on cell cultures. These results may suggest a good alternative to develop new endodontic sealers, in order to achieve better biological response and healing, when compared to commercially available sealers.

  3. Sensitivity-based approach to optimal experimental design in a receptor trafficking and down regulation model

    Science.gov (United States)

    Casey, Fergal; Waterfall, Joshua; Gutenkunst, Ryan; Brown, Kevin; Myers, Christopher; Sethna, James

    2006-03-01

    We apply the ideas of optimal experimental design to systems biology models: minimizing a design criterion based on the average variance of predictions, we suggest new experiments that need to be performed to optimally test a given biological hypothesis. The estimated variance in predictions is derived from the sensitivities of protein and chemical species in the model to changes in reaction rates. The sensitivities also allow us to determine which interactions in the biological network dominate the system behavior. To test the design principles, we have developed a differential equation model incorporating the processes of endocytosis, recycling and degradation of activated epidermal growth factor (EGF) receptor in a mammalian cell line. Recent experimental work has discovered mutant proteins that cause receptor accumulation and a prolonged growth signal. Our model is optimized to fit this mutant experimental data and wild type data for a variety of experimental conditions. Of biological interest is the effect on surface and internalized receptor levels after the overexpression or inactivation of regulator proteins in the network: the optimal design method allows us to fine tune the conditions to best predict the behavior of these unknown components of the system.

  4. Experimental and AI-based numerical modeling of contaminant transport in porous media

    Science.gov (United States)

    Nourani, Vahid; Mousavi, Shahram; Sadikoglu, Fahreddin; Singh, Vijay P.

    2017-10-01

    This study developed a new hybrid artificial intelligence (AI)-meshless approach for modeling contaminant transport in porous media. The key innovation of the proposed approach is that both black box and physically-based models are combined for modeling contaminant transport. The effectiveness of the approach was evaluated using experimental and real world data. Artificial neural network (ANN) and adaptive neuro-fuzzy inference system (ANFIS) were calibrated to predict temporal contaminant concentrations (CCs), and the effect of noisy and de-noised data on the model performance was evaluated. Then, considering the predicted CCs at test points (TPs, in experimental study) and piezometers (in Myandoab plain) as interior conditions, the multiquadric radial basis function (MQ-RBF), as a meshless approach which solves partial differential equation (PDE) of contaminant transport in porous media, was employed to estimate the CC values at any point within the study area where there was no TP or piezometer. Optimal values of the dispersion coefficient in the advection-dispersion PDE and shape coefficient of MQ-RBF were determined using the imperialist competitive algorithm. In temporal contaminant transport modeling, de-noised data enhanced the performance of ANN and ANFIS methods in terms of the determination coefficient, up to 6 and 5%, respectively, in the experimental study and up to 39 and 18%, respectively, in the field study. Results showed that the efficiency of ANFIS-meshless model was more than ANN-meshless model up to 2 and 13% in the experimental and field studies, respectively.

  5. Application of iterative robust model-based optimal experimental design for the calibration of biocatalytic models.

    Science.gov (United States)

    Van Daele, Timothy; Gernaey, Krist V; Ringborg, Rolf H; Börner, Tim; Heintz, Søren; Van Hauwermeiren, Daan; Grey, Carl; Krühne, Ulrich; Adlercreutz, Patrick; Nopens, Ingmar

    2017-09-01

    The aim of model calibration is to estimate unique parameter values from available experimental data, here applied to a biocatalytic process. The traditional approach of first gathering data followed by performing a model calibration is inefficient, since the information gathered during experimentation is not actively used to optimize the experimental design. By applying an iterative robust model-based optimal experimental design, the limited amount of data collected is used to design additional informative experiments. The algorithm is used here to calibrate the initial reaction rate of an ω-transaminase catalyzed reaction in a more accurate way. The parameter confidence region estimated from the Fisher Information Matrix is compared with the likelihood confidence region, which is not only more accurate but also a computationally more expensive method. As a result, an important deviation between both approaches is found, confirming that linearization methods should be applied with care for nonlinear models. © 2017 American Institute of Chemical Engineers Biotechnol. Prog., 33:1278-1293, 2017. © 2017 American Institute of Chemical Engineers.

  6. Transmission characteristics of the S0 and A0 Lamb waves at contacting edges of plates.

    Science.gov (United States)

    Mori, Naoki; Biwa, Shiro

    2017-11-01

    In order to gain basic insight into the interaction between ultrasonic guided waves and structural discontinuities with contacting surfaces, the transmission characteristics of Lamb waves at contacting edges of two plates are studied experimentally. The edges of two 2.5-mm thick aluminum alloy plates are mated together to constitute a contacting interface of plates and subjected to different levels of compressive loading. The transmission measurements of the lowest-order symmetric (S0) and antisymmetric (A0) Lamb modes across the contacting interface are performed in a frequency range below the cut-off frequencies of the higher-order modes. As a result, it is found that the transmission coefficient of the S0 mode increases monotonically with the applied contact pressure, but the transmission coefficient of the A0 mode exhibits non-monotonic dependence on the contact pressure and the frequency showing a local minimum. For the incidence of the S0 mode, the resonance at the contacting interface is observed as a long-time oscillation tail in the transmission waveform. The resonance frequency is found to increase with the contact pressure. The experimental results are discussed in the light of the theoretical results based on the spring-type interface model. The normal and tangential stiffnesses of the contacting interface are identified from the transmission coefficients as well as from the resonance frequency. The estimated interfacial stiffnesses increase monotonically with the contact pressure, and indicate their dependence on the frequency. Implications of the present results to the Lamb-wave based characterization of the plate contact condition are discussed briefly. Copyright © 2017 Elsevier B.V. All rights reserved.

  7. An experimental investigation on performance of fins on a horizontal base in free convection heat transfer

    Energy Technology Data Exchange (ETDEWEB)

    Guevenc, A.; Yuencue, H. [Dept. of Mechanical Engineering, Middle East Technical Univ., Ankara (Turkey)

    2001-07-01

    Natural convection heat transfer in rectangular fin-arrays mounted on a vertical base was investigated experimentally. An experimental set-up was constructed and calibrated to test 15 different fin configurations. Fin length and fin thickness were kept fixed at 100 and 3 mm respectively, while fin spacing was varied from 4.5 to 58.75 mm and fin height was varied from 5 to 25 mm. Base-to-ambient temperature difference was also varied through a calibrated wattmeter ranging from 10 to 50 W. The results showed that fin spacing is the most significant parameter in the performance of fin arrays; and for every fin height, for a given base-to-ambient temperature difference, there exists an optimum value for the fin spacing for which the heat transfer rate from the fin array is maximized. It was seen that higher heat transfer enhancement are obtained with vertically oriented bases than with horizontally oriented bases for fin arrays of the same geometry. (orig.)

  8. Web-Based Treatment Program Using Intensive Therapeutic Contact for Patients With Eating Disorders: Before-After Study

    NARCIS (Netherlands)

    Huurne, E.D. ter; Postel, M.G.; Haan, H.A. de; Drossaert, C.H.C.; Jong, C.A.J. de

    2013-01-01

    Background: Although eating disorders are common in the Netherlands, only a few patients are treated by mental health care professionals. To reach and treat more patients with eating disorders, Tactus Addiction Treatment developed a web-based treatment program with asynchronous and intensive

  9. A quantitative and non-contact technique to characterise microstructural variations of skin tissues during photo-damaging process based on Mueller matrix polarimetry.

    Science.gov (United States)

    Dong, Yang; He, Honghui; Sheng, Wei; Wu, Jian; Ma, Hui

    2017-10-31

    Skin tissue consists of collagen and elastic fibres, which are highly susceptible to damage when exposed to ultraviolet radiation (UVR), leading to skin aging and cancer. However, a lack of non-invasive detection methods makes determining the degree of UVR damage to skin in real time difficult. As one of the fundamental features of light, polarization can be used to develop imaging techniques capable of providing structural information about tissues. In particular, Mueller matrix polarimetry is suitable for detecting changes in collagen and elastic fibres. Here, we demonstrate a novel, quantitative, non-contact and in situ technique based on Mueller matrix polarimetry for monitoring the microstructural changes of skin tissues during UVR-induced photo-damaging. We measured the Mueller matrices of nude mouse skin samples, then analysed the transformed parameters to characterise microstructural changes during the skin photo-damaging and self-repairing processes. Comparisons between samples with and without the application of a sunscreen showed that the Mueller matrix-derived parameters are potential indicators for fibrous microstructure in skin tissues. Histological examination and Monte Carlo simulations confirmed the relationship between the Mueller matrix parameters and changes to fibrous structures. This technique paves the way for non-contact evaluation of skin structure in cosmetics and dermatological health.

  10. A 3D contact analysis approach for the visualization of the electrical contact asperities

    Science.gov (United States)

    Swingler, Jonathan

    2017-01-01

    The electrical contact is an important phenomenon that should be given into consideration to achieve better performance and long term reliability for the design of devices. Based upon this importance, the electrical contact interface has been visualized as a ‘‘3D Contact Map’’ and used in order to investigate the contact asperities. The contact asperities describe the structures above and below the contact spots (the contact spots define the 3D contact map) to the two conductors which make the contact system. The contact asperities require the discretization of the 3D microstructures of the contact system into voxels. A contact analysis approach has been developed and introduced in this paper which shows the way to the 3D visualization of the contact asperities of a given contact system. For the discretization of 3D microstructure of contact system into voxels, X-ray Computed Tomography (CT) method is used in order to collect the data of a 250 V, 16 A rated AC single pole rocker switch which is used as a contact system for investigation. PMID:28105383

  11. Enhancing the approach to selecting eyewear (EASE): a multi-centre, practice-based study into the effect of applying contact lenses prior to spectacle dispensing.

    Science.gov (United States)

    Atkins, Nick P; Morgan, Sarah L; Morgan, Philip B

    2009-06-01

    To examine the impact of contact lens application in non-contact lens wearers prior to spectacle dispensing. Ninety-one eligible subjects with no previous contact lens experience were randomly assigned into either a test group (52 subjects) or control group (39 subjects). The former group was offered contact lenses before spectacle dispensing. The latter group proceeded to spectacle dispensing in the normal way without being offered contact lenses. The response to the offer of contact lenses, fit success, the impact on the spectacle dispensing process and the longer term purchase of contact lenses were measured and compared for the test and control groups. Of the test group, 46 (88%) agreed to try contact lenses. All subjects were suitable for contact lenses after a slit lamp examination and lenses were successfully fitted to 45 of the 46 subjects (98%). The test group reported a superior subjective spectacle dispensing experience and spent 267+/-143 pounds (mean+/-standard deviation) on their spectacle frames and lenses, 32% more than the control group (202+/-128 pounds). At 3 months post dispensing, 17 test patients (33% of original cohort) had purchased contact lenses compared with five control subjects (13%) (p=0.001). The opportunity to try contact lenses prior to spectacle dispensing was well received by subjects who generally reported a very positive experience. In particular, contact lenses assisted in seeing frame detail and suitability for wear. One third of subjects proceeded to purchase contact lenses. We recommend that practitioners consider offering contact lenses to all suitable patients who are proceeding to spectacle dispensing to optimise the dispensing process and to provide an opportunity to try contact lenses.

  12. [Contact lens-related keratitis].

    Science.gov (United States)

    Steiber, Zita; Berta, András; Módis, László

    2013-11-10

    Nowadays, keratitis, corneal infection due to wearing contact lens means an increasingly serious problem. Neglected cases may lead to corneal damage that can cause blindness in cases of otherwise healthy eyes. Early diagnosis based on the clinical picture and the typical patient history is an important way of prevention. Prophylaxis is substantial to avoid bacterial and viral infection that is highly essential in this group of diseases. Teaching contact lens wearers the proper contact lens care, storage, sterility, and hygiene regulations is of great importance. In case of corneal inflammation early accurate diagnosis supported by microbiological culture from contact lenses, storage boxes or cornea is very useful. Thereafter, targeted drug therapy or in therapy-resistant cases surgical treatment may even be necessary in order to sustain suitable visual acuity.

  13. Evaluation of process influences on surface chemistry of epoxy acrylate based solder mask via XPS, ToF-SIMS and contact angle measurement

    Energy Technology Data Exchange (ETDEWEB)

    Hofmeister, Caroline, E-mail: caroline.hofmeister@de.bosch.com [Robert Bosch GmbH, Postfach 30 02 40, 70442 Stuttgart (Germany); Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM, Wiener Str. 12, 28359 Bremen (Germany); Maaß, Sebastian [Robert Bosch GmbH, Postfach 30 02 40, 70442 Stuttgart (Germany); Fladung, Thorsten; Mayer, Bernd [Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM, Wiener Str. 12, 28359 Bremen (Germany)

    2017-01-01

    Epoxy acrylate based solder mask formulations were conditioned by different printed circuit board (PCB) manufacturing and PCB assembly process stages. Depending on these different influences the chemistry of the solder mask surface was investigated regarding adhesion to possible adhesion partners. The combination of X-ray photoelectron spectrometry (XPS), time-of-flight secondary ion mass spectrometry (ToF-SIMS) and the contact angle method, for surface energy determination, provided a detailed understanding of the surface near region up to the topmost monolayer, which forms the contact zone in which adhesion takes place. The combination of ToF-SIMS and XPS provided molecular information of surface components comprising quantitative information. The influences of all process steps, like UV, chemical and thermal treatment, on the chemical surface composition and appearance were identified. Based on the results a chemical surface model could be created regarding the different adhesion mechanisms. It has been shown that an enrichment of siloxanes at the surface is generated by different mechanisms that were distinguished based on ToF-SIMS. Even though an oxidation process in the surface near region (10 nm) was indicated by XPS, no increase of the surface polar groups and thus no polarity increase could be observed within the first monolayer. A surface model derived from the analysis results shows generation and occupation of free sites at the surface through all stages of the process. An occupation of free sites by siloxanes from additives in the solder mask formulation results in a siloxane dominated topmost monolayer. - Highlights: • A surface model describing the process influences is proposed. • Detailed siloxane reaction analysis was possible with ToF-SIMS. • Photo-chemical, chemical and thermal surface modification occur during PCB manufacturing.

  14. Experimental Simulation-Based Performance Evaluation of an SMS-Based Emergency Geolocation Notification System

    OpenAIRE

    Isibor Osebor; Sanjay Misra; Nicholas Omoregbe; Adewole Adewumi; Luis Fernandez-Sanz

    2017-01-01

    In an emergency, a prompt response can save the lives of victims. This statement generates an imperative issue in emergency medical services (EMS). Designing a system that brings simplicity in locating emergency scenes is a step towards improving response time. This paper therefore implemented and evaluated the performance of an SMS-based emergency geolocation notification system with emphasis on its SMS delivery time and the system’s geolocation and dispatch time. Using the RAS metrics recom...

  15. Experimentation and problem-based learning as alternative for the science teaching

    Directory of Open Access Journals (Sweden)

    C.B. Soares

    2012-05-01

    Full Text Available Experimentation  and  problem-based  learning  may  aid  to  diminish  the  lack  of student  interest  in  science  teaching  and  its  contents.  These  tools  help  in understanding and in approaches in the scientific method to contextualize and give meaning to science teaching. Thus, this descriptive study presents an alternative developed from experimental activities carried out in short courses to 185 students from public schools in Uruguaiana-RS. With the problem-based learning, seven courses were offered in the period 2010-2011 lasting for five days. The courses were divided into four stages: problematization, with the theme "The food and our health";  experiment  and  theory,  these  phases  occur  together,  where  students define  the  protocol  to  be  followed  in  order  to  try  to  answer  questions experimentally using books and internet to sustain the practice theoretically; and closing, the students show the results of experiments carried out during the course through  theater,  music,  posters  or  slides.  Since  students  are  the  agents responsible for the development of this work the experimental activities through learning situations based on problems triggered a strong interest and involvement of students in the school contents. In conclusion, this method of experimentation and problem-based learning instigates the interest by scientific knowledge and turns the teaching of science in a practice innovative teaching.

  16. Layout optimization with assist features placement by model based rule tables for 2x node random contact

    Science.gov (United States)

    Jun, Jinhyuck; Park, Minwoo; Park, Chanha; Yang, Hyunjo; Yim, Donggyu; Do, Munhoe; Lee, Dongchan; Kim, Taehoon; Choi, Junghoe; Luk-Pat, Gerard; Miloslavsky, Alex

    2015-03-01

    As the industry pushes to ever more complex illumination schemes to increase resolution for next generation memory and logic circuits, sub-resolution assist feature (SRAF) placement requirements become increasingly severe. Therefore device manufacturers are evaluating improvements in SRAF placement algorithms which do not sacrifice main feature (MF) patterning capability. There are known-well several methods to generate SRAF such as Rule based Assist Features (RBAF), Model Based Assist Features (MBAF) and Hybrid Assisted Features combining features of the different algorithms using both RBAF and MBAF. Rule Based Assist Features (RBAF) continue to be deployed, even with the availability of Model Based Assist Features (MBAF) and Inverse Lithography Technology (ILT). Certainly for the 3x nm node, and even at the 2x nm nodes and lower, RBAF is used because it demands less run time and provides better consistency. Since RBAF is needed now and in the future, what is also needed is a faster method to create the AF rule tables. The current method typically involves making masks and printing wafers that contain several experiments, varying the main feature configurations, AF configurations, dose conditions, and defocus conditions - this is a time consuming and expensive process. In addition, as the technology node shrinks, wafer process changes and source shape redesigns occur more frequently, escalating the cost of rule table creation. Furthermore, as the demand on process margin escalates, there is a greater need for multiple rule tables: each tailored to a specific set of main-feature configurations. Model Assisted Rule Tables(MART) creates a set of test patterns, and evaluates the simulated CD at nominal conditions, defocused conditions and off-dose conditions. It also uses lithographic simulation to evaluate the likelihood of AF printing. It then analyzes the simulation data to automatically create AF rule tables. It means that analysis results display the cost of

  17. Model-based experimental design for assessing effects of mixtures of chemicals

    Energy Technology Data Exchange (ETDEWEB)

    Baas, Jan, E-mail: jan.baas@falw.vu.n [Vrije Universiteit of Amsterdam, Dept of Theoretical Biology, De Boelelaan 1085, 1081 HV Amsterdam (Netherlands); Stefanowicz, Anna M., E-mail: anna.stefanowicz@uj.edu.p [Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30-387 Krakow (Poland); Klimek, Beata, E-mail: beata.klimek@uj.edu.p [Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30-387 Krakow (Poland); Laskowski, Ryszard, E-mail: ryszard.laskowski@uj.edu.p [Institute of Environmental Sciences, Jagiellonian University, Gronostajowa 7, 30-387 Krakow (Poland); Kooijman, Sebastiaan A.L.M., E-mail: bas@bio.vu.n [Vrije Universiteit of Amsterdam, Dept of Theoretical Biology, De Boelelaan 1085, 1081 HV Amsterdam (Netherlands)

    2010-01-15

    We exposed flour beetles (Tribolium castaneum) to a mixture of four poly aromatic hydrocarbons (PAHs). The experimental setup was chosen such that the emphasis was on assessing partial effects. We interpreted the effects of the mixture by a process-based model, with a threshold concentration for effects on survival. The behavior of the threshold concentration was one of the key features of this research. We showed that the threshold concentration is shared by toxicants with the same mode of action, which gives a mechanistic explanation for the observation that toxic effects in mixtures may occur in concentration ranges where the individual components do not show effects. Our approach gives reliable predictions of partial effects on survival and allows for a reduction of experimental effort in assessing effects of mixtures, extrapolations to other mixtures, other points in time, or in a wider perspective to other organisms. - We show a mechanistic approach to assess effects of mixtures in low concentrations.

  18. Methodology to estimate parameters of an excitation system based on experimental conditions

    Energy Technology Data Exchange (ETDEWEB)

    Saavedra-Montes, A.J. [Carrera 80 No 65-223, Bloque M8 oficina 113, Escuela de Mecatronica, Universidad Nacional de Colombia, Medellin (Colombia); Calle 13 No 100-00, Escuela de Ingenieria Electrica y Electronica, Universidad del Valle, Cali, Valle (Colombia); Ramirez-Scarpetta, J.M. [Calle 13 No 100-00, Escuela de Ingenieria Electrica y Electronica, Universidad del Valle, Cali, Valle (Colombia); Malik, O.P. [2500 University Drive N.W., Electrical and Computer Engineering Department, University of Calgary, Calgary, Alberta (Canada)

    2011-01-15

    A methodology to estimate the parameters of a potential-source controlled rectifier excitation system model is presented in this paper. The proposed parameter estimation methodology is based on the characteristics of the excitation system. A comparison of two pseudo random binary signals, two sampling periods for each one, and three estimation algorithms is also presented. Simulation results from an excitation control system model and experimental results from an excitation system of a power laboratory setup are obtained. To apply the proposed methodology, the excitation system parameters are identified at two different levels of the generator saturation curve. The results show that it is possible to estimate the parameters of the standard model of an excitation system, recording two signals and the system operating in closed loop with the generator. The normalized sum of squared error obtained with experimental data is below 10%, and with simulation data is below 5%. (author)

  19. Impacts of radiation exposure on the experimental microbial ecosystem: a particle-based model simulation approach

    Energy Technology Data Exchange (ETDEWEB)

    Doi, M.; Tanaka, N.; Fuma, S.; Kawabata, Z.

    2004-07-01

    Well-designed experimental model ecosystem could be a simple reference of the actual environment and complex ecological systems. For ecological toxicity test of radiation and other environmental toxicants, we investigated and aquatic microbial ecosystem (closed microcosm) in the test tube with initial substrates,autotroph flagellate algae (Euglena, G.), heterotroph ciliate protozoa (Tetrahymena T.) and saprotroph bacteria (E, coli). These species organizes by itself to construct the ecological system, that keeps the sustainable population dynamics for more than 2 years after inoculation only by adding light diurnally and controlling temperature at 25 degree Celsius. Objective of the study is to develop the particle-based computer simulation by reviewing interactions among microbes and environment, and analyze the ecological toxicities of radiation on the microcosm by replicating experimental results in the computer simulation. (Author) 14 refs.

  20. Correction of Magnetic Optics and Beam Trajectory Using LOCO Based Algorithm with Expanded Experimental Data Sets

    Energy Technology Data Exchange (ETDEWEB)

    Romanov, A.; Edstrom, D.; Emanov, F. A.; Koop, I. A.; Perevedentsev, E. A.; Rogovsky, Yu. A.; Shwartz, D. B.; Valishev, A.

    2017-03-28

    Precise beam based measurement and correction of magnetic optics is essential for the successful operation of accelerators. The LOCO algorithm is a proven and reliable tool, which in some situations can be improved by using a broader class of experimental data. The standard data sets for LOCO include the closed orbit responses to dipole corrector variation, dispersion, and betatron tunes. This paper discusses the benefits from augmenting the data with four additional classes of experimental data: the beam shape measured with beam profile monitors; responses of closed orbit bumps to focusing field variations; betatron tune responses to focusing field variations; BPM-to-BPM betatron phase advances and beta functions in BPMs from turn-by-turn coordinates of kicked beam. All of the described features were implemented in the Sixdsimulation software that was used to correct the optics of the VEPP-2000 collider, the VEPP-5 injector booster ring, and the FAST linac.

  1. Crane-Load Contact Sensor

    Science.gov (United States)

    Youngquist, Robert; Mata, Carlos; Cox, Robert

    2005-01-01

    An electronic instrument has been developed as a prototype of a portable crane-load contact sensor. Such a sensor could be helpful in an application in which the load rests on a base in a horizontal position determined by vertical alignment pins (see Figure 1). If the crane is not positioned to lift the load precisely vertically, then the load can be expected to swing once it has been lifted clear of the pins. If the load is especially heavy, large, and/or fragile, it could hurt workers and/or damage itself and nearby objects. By indicating whether the load remains in contact with the pins when it has been lifted a fraction of the length of the pins, the crane-load contact sensor helps the crane operator determine whether it is safe to lift the load clear of the pins: If there is contact, then the load is resting against the sides of the pins and, hence, it may not be safe to lift; if contact is occasionally broken, then the load is probably not resting against the pins, so it should be safe to lift. It is assumed that the load and base, or at least the pins and the surfaces of the alignment holes in the load, are electrically conductive, so the instrument can use electrical contact to indicate mechanical contact. However, DC resistance cannot be used as an indicator of contact for the following reasons: The load and the base are both electrically grounded through cables (the load is grounded through the lifting cable of the crane) to prevent discharge of static electricity. In other words, the DC resistance between the load and the pins is always low, as though they were always in direct contact. Therefore, instead of DC resistance, the instrument utilizes the AC electrical impedance between the pins and the load. The signal frequency used in the measurement is high enough (.1 MHz) that the impedance contributed by the cables and the electrical ground network of the building in which the crane and the base are situated is significantly greater than the contact

  2. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Halloween is a popular time for people to use colored contact lenses to enhance their costumes. From ... Blurry Vision and Daily Eye Drops After One Use Facts About Colored Contacts and Halloween Safety Colored ...

  3. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... glow-in-the-dark lizard lenses, costume contacts can certainly add a spooky, eye-popping touch. But ... consideration as a standard contact lens because they can be purchased over-the-counter or on the ...

  4. Contact Us about Asbestos

    Science.gov (United States)

    How to contact EPA for more information on asbestos, including state and regional contacts, EPA’s Asbestos Abatement/Management Ombudsman and the Toxic Substances Control Act (TSCA) Assistance Information Service (TSCA Hotline).

  5. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Cleveland. "This is far from the truth." Real People, Real Problems with Colored Contact Lenses Julian: Teenager ... Counter Costume Contact Lenses Can Ruin Vision Eye Makeup Safety In fact, it is illegal to sell ...

  6. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses you are considering ... Follow The Academy Professionals: Education Guidelines News Multimedia Public & Patients: Contact Us About the Academy Jobs at ...

  7. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... popping touch. But colored contact lenses are popular year-round, not just at Halloween. But few know ... contact lenses for Halloween or any time of year, follow these guidelines: Get an eye exam from ...

  8. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... like a suction cup." Halloween is a popular time for people to use colored contact lenses to ... wear costume contact lenses for Halloween or any time of year, follow these guidelines: Get an eye ...

  9. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... is far from the truth." Real People, Real Problems with Colored Contact Lenses Julian: Teenager Blinded In ... colored contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses you are ...

  10. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... Contact Lens Facts Over-the-Counter Costume Contacts May Contain Chemicals Harmful to Eyes Four Ways Over- ... without a prescription are breaking the law, and may be fined $11,000 per violation. "Many of ...

  11. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... contact lenses , from the U.S. Food and Drug Administration (FDA). Are the colored lenses you are considering buying approved by the FDA? Check the FDA's database of approved contact lenses . Related Stories Gene Therapy ...

  12. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... and are being sold illegally," Dr. Steinemann said. Never buy colored contact lenses from a retailer that ... directions for cleaning, disinfecting, and wearing the lenses. Never share contact lenses with another person. Get follow ...

  13. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... buy colored contact lenses from a retailer that does not ask for a prescription. There is no ... of approved contact lenses . Related Stories How long does it take the eye to go back to ...

  14. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... One Use Facts About Colored Contacts and Halloween Safety Colored Contact Lens Facts Over-the-Counter Costume ... new application of artificial intelligence shows whether a patient’s eyes point to high blood pressure or risk ...

  15. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... in a pair of colored contact lenses, Laura Butler of Parkersburg, W.Va., had "extreme pain in ... to wear any kind of contact lens. In Butler's case, the lenses caused an infection and left ...

  16. Colored Contact Lens Dangers

    Medline Plus

    Full Text Available ... contact lenses, remove the lenses and seek immediate medical attention from an ophthalmologist. Related resources: Learn how to properly care for contact lenses . Learn about the members of ...

  17. Tribological Properties of Ti-Based Alloys in a Simulated Bone-Implant Interface with Ringer's Solution at Fretting Contacts

    OpenAIRE

    Ramos-Saenz, C.R.; Sundaram, P.A.; Diffoot-Carlo, N.

    2010-01-01

    The wear properties of oxidized and non-oxidized gamma-TiAl (a potential biomaterial) as well as Ti-6Al-4V and CP-Ti disks were studied and characterized by means of standard wear tests using a custom made bone pin arrangement. The Ti-base disks were oxidized in air at 500°C and 800°C for one hour. The tribological properties of the oxides formed over the disks were studied using a linear reciprocating wear testing machine under both dry and simulated biological conditions using Ringer's solu...

  18. A composite experimental dynamic substructuring method based on partitioned algorithms and localized Lagrange multipliers

    Science.gov (United States)

    Abbiati, Giuseppe; La Salandra, Vincenzo; Bursi, Oreste S.; Caracoglia, Luca

    2018-02-01

    Successful online hybrid (numerical/physical) dynamic substructuring simulations have shown their potential in enabling realistic dynamic analysis of almost any type of non-linear structural system (e.g., an as-built/isolated viaduct, a petrochemical piping system subjected to non-stationary seismic loading, etc.). Moreover, owing to faster and more accurate testing equipment, a number of different offline experimental substructuring methods, operating both in time (e.g. the impulse-based substructuring) and frequency domains (i.e. the Lagrange multiplier frequency-based substructuring), have been employed in mechanical engineering to examine dynamic substructure coupling. Numerous studies have dealt with the above-mentioned methods and with consequent uncertainty propagation issues, either associated with experimental errors or modelling assumptions. Nonetheless, a limited number of publications have systematically cross-examined the performance of the various Experimental Dynamic Substructuring (EDS) methods and the possibility of their exploitation in a complementary way to expedite a hybrid experiment/numerical simulation. From this perspective, this paper performs a comparative uncertainty propagation analysis of three EDS algorithms for coupling physical and numerical subdomains with a dual assembly approach based on localized Lagrange multipliers. The main results and comparisons are based on a series of Monte Carlo simulations carried out on a five-DoF linear/non-linear chain-like systems that include typical aleatoric uncertainties emerging from measurement errors and excitation loads. In addition, we propose a new Composite-EDS (C-EDS) method to fuse both online and offline algorithms into a unique simulator. Capitalizing from the results of a more complex case study composed of a coupled isolated tank-piping system, we provide a feasible way to employ the C-EDS method when nonlinearities and multi-point constraints are present in the emulated system.

  19. A Fault Diagnosis Method of High Voltage Circuit Breaker Based on Moving Contact Motion Trajectory and ELM

    Directory of Open Access Journals (Sweden)

    Weihua Niu

    2016-01-01

    Full Text Available In order to avoid the deficiencies of conventional high voltage circuit breaker mechanical properties detection methods, a new algorithm based on image block matching with diamond search strategy is presented in this paper. The motion of auxiliary mark on the pull rod or shaft is firstly recorded by a high-speed and high-definition digital camera when the circuit breaker is open or close. Then the motion trajectory is acquired through diamond image block matching method. The mechanical parameters, such as travel and open and close velocity, are calculated according to the travel-time curve of the circuit breaker. Finally, evaluation model is constructed taking mechanical parameters characteristic values as inputs of ELM. Comparing to the existing techniques, our method is a noncontact measurement based on computer vision. It is easy and convenient for practical application since it need not any electrical and mechanical connection to the breaker. Another advantage of our method is that it can obtain the line and angle displacement simultaneously. The experiment results on the circuit breaker of 220 kv show that our method is effective for breaker mechanical properties detection.

  20. Contact Lenses - A Review

    OpenAIRE

    Dada V; Sharma Rajiv

    1987-01-01

    A review of recent literature on contact lenses shows increasingly more studies on soft contact lenses than PMMA hard lenses The articles on contact lens wear and ulcerative keratitis have highlighted the increased risk of microbial keratitis in contact lens wearers compared to the general population, higher virulence of pathogens isolated and special association of fungi with EWSCL This high risk is due to multiple factors, organism survival in moist lens cases and cleaning solutions, microt...