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Sample records for experimental background due

  1. Machine Induced Experimental Background Conditions in the LHC

    CERN Document Server

    Levinsen, Yngve Inntjore; Stapnes, Steinar

    2012-09-19

    The Large Hadron Collider set a new energy record for particle accelerators in late 2009, breaking the previous record held by Tevatron of 2 TeV collision energy. The LHC today operates at a collision energy of 7 TeV. With higher beam energy and intensity, measures have to be taken to ensure optimal experimental conditions and safety of the machine and detectors. Machine induced experimental background can severely reduce the quality of experimental triggers and track reconstruction. In a worst case, the radiation levels can be damaging for some of the subdetectors. The LHC is a particular challenge in this regard due to the vastly different operating conditions of the different experiments. The nominal luminosity varies by four orders of magnitude. The unprecedented stored beam energy and the amount of superconducting elements can make it challenging to protect the accelerator itself as well. In this work we have simulated and measured the machine induced background originating from various sources: the beam...

  2. Stochastic Gravitational-Wave Background due to Primordial Binary Black Hole Mergers.

    Science.gov (United States)

    Mandic, Vuk; Bird, Simeon; Cholis, Ilias

    2016-11-11

    Recent Advanced LIGO detections of binary black hole mergers have prompted multiple studies investigating the possibility that the heavy GW150914 binary system was of primordial origin, and hence could be evidence for dark matter in the form of black holes. We compute the stochastic background arising from the incoherent superposition of such primordial binary black hole systems in the Universe and compare it to the similar background spectrum due to binary black hole systems of stellar origin. We investigate the possibility of detecting this background with future gravitational-wave detectors, and conclude that constraining the dark matter component in the form of black holes using stochastic gravitational-wave background measurements will be very challenging.

  3. Detection of enhancement in number densities of background galaxies due to magnification by massive galaxy clusters

    Energy Technology Data Exchange (ETDEWEB)

    Chiu, I.; Dietrich, J. P.; Mohr, J.; Applegate, D. E.; Benson, B. A.; Bleem, L. E.; Bayliss, M. B.; Bocquet, S.; Carlstrom, J. E.; Capasso, R.; Desai, S.; Gangkofner, C.; Gonzalez, A. H.; Gupta, N.; Hennig, C.; Hoekstra, H.; von der Linden, A.; Liu, J.; McDonald, M.; Reichardt, C. L.; Saro, A.; Schrabback, T.; Strazzullo, V.; Stubbs, C. W.; Zenteno, A.

    2016-02-18

    We present a detection of the enhancement in the number densities of background galaxies induced from lensing magnification and use it to test the Sunyaev-Zel'dovich effect (SZE-) inferred masses in a sample of 19 galaxy clusters with median redshift z similar or equal to 0.42 selected from the South Pole Telescope SPT-SZ survey. These clusters are observed by the Megacam on the Magellan Clay Telescope though gri filters. Two background galaxy populations are selected for this study through their photometric colours; they have median redshifts zmedian similar or equal to 0.9 (low-z background) and z(median) similar or equal to 1.8 (high-z background). Stacking these populations, we detect the magnification bias effect at 3.3 sigma and 1.3 sigma for the low-and high-z backgrounds, respectively. We fit Navarro, Frenk and White models simultaneously to all observed magnification bias profiles to estimate the multiplicative factor. that describes the ratio of the weak lensing mass to the mass inferred from the SZE observable-mass relation. We further quantify systematic uncertainties in. resulting from the photometric noise and bias, the cluster galaxy contamination and the estimations of the background properties. The resulting. for the combined background populations with 1 sigma uncertainties is 0.83 +/- 0.24(stat) +/- 0.074(sys), indicating good consistency between the lensing and the SZE-inferred masses. We use our best-fitting eta to predict the weak lensing shear profiles and compare these predictions with observations, showing agreement between the magnification and shear mass constraints. This work demonstrates the promise of using the magnification as a complementary method to estimate cluster masses in large surveys.

  4. Positive streamer propagation due to background or photo ionization: Experiments and theory

    NARCIS (Netherlands)

    S. Nijdam (Sander); G. Wormeester (Gideon); U. Ebert (Ute)

    2012-01-01

    textabstractPositive streamers in air are generally believed to propagate against the electron drift direction due to the nonlocal photo-ionization reaction. Photo-ionization is the ionization of O2 molecules by UV radiation from excited N2 molecules; therefore this reaction depends on the ratio

  5. Global Health Benefits from Reductions in Background Tropospheric Ozone due to Methane Emission Controls

    Science.gov (United States)

    West, J. J.; Mauzerall, D. L.; Fiore, A. M.; Horowitz, L. W.

    2005-05-01

    Increases in background ozone throughout the troposphere are partially attributed to rising anthropogenic methane concentrations, which are projected to continue to increase in the future. Because methane is long-lived and affects background ozone, controls on methane emissions would reduce surface ozone concentrations fairly uniformly around the globe. Epidemiological research indicates that exposure to ozone increases incidence of respiratory ailments and premature mortality. In addition, exposure to ozone reduces agricultural yields and damages natural ecosystems. We use the MOZART-2 global atmospheric chemistry and transport model to estimate the effects on global surface ozone of perturbations in methane emissions. We consider a baseline scenario for 2000 and the 2030 A2 scenario (emissions from the IPCC AR-4 2030 atmospheric chemistry experiments), and examine the impact on ozone of decreasing anthropogenic methane emissions relative to this baseline by 20%. Using the simulated spatially-distributed decreases in surface ozone concentrations resulting from these reductions in methane emissions, we estimate the global benefits to human health in the methane emission reduction scenario. We focus on human mortality, and consider the sensitivity of our estimates to different assumptions of health effect thresholds at low ozone concentrations.

  6. Degradation of signal to noise ratio in optical free space data links due to background illumination.

    Science.gov (United States)

    Leeb, W R

    1989-08-15

    In free space optical data transmission systems illumination of the receiver antenna by background radiation will decrease the signal to noise ratio. We derive expressions for that degradation both for direct and for heterodyne/homodyne receivers. Examples are given for cases where the sun, the moon, the earth, and Venus illuminate earth orbiting receivers operating at wavelengths of 0.85 microm, 1.3 microm, and 10.6 microm. Direct detection receivers will typically suffer a degradation of between 5 and 15 dB at lambda = 0.85 microm and lambda = 1.3 microm when illuminated by the sun. Heterodyne/homodyne receivers at 10.6 microm degrade more with sun radiation (typically 4 dB) than at the smaller wavelengths ( approximately 0.3 dB). The moon, earth, and Venus cause negligible reduction of signal to noise ratio.

  7. Beam loss and backgrounds in the CDF and D0 detectors due to nuclear elastic beam-gas scattering

    Energy Technology Data Exchange (ETDEWEB)

    Alexandr I. Drozhdin; Valery A. Lebedev; Nikolai V. Mokhov

    2003-05-27

    Detailed simulations were performed on beam loss rates in the vicinity of the Tevatron Collider detectors due to beam-gas nuclear elastic interactions. It turns out that this component can drive the accelerator-related background rates in the CDF and D0 detectors, exceeding those due to outscattering from collimation system, inelastic beam-gas interactions and other processes [1, 2]. Results of realistic simulations with the STRUCT and MARS codes are presented for the interaction region components and the CDF and D0 detectors. It is shown that a steel mask placed upstream of the detectors can reduce the background rates by almost an order of magnitude.

  8. Radiation and Background Levels in a CLIC Detector due to Beam-Beam Effects Optimisation of Detector Geometries and Technologies

    CERN Document Server

    Sailer, André; Lohse, Thomas

    2013-01-10

    The high charge density---due to small beam sizes---and the high energy of the proposed CLIC concept for a linear electron--positron collider with a centre-of-mass energy of up to 3~TeV lead to the production of a large number of particles through beam-beam interactions at the interaction point during every bunch crossing (BX). A large fraction of these particles safely leaves the detector. A still significant amount of energy will be deposited in the forward region nonetheless, which will produce secondary particles able to cause background in the detector. Furthermore, some particles will be created with large polar angles and directly cause background in the tracking detectors and calorimeters. The main sources of background in the detector, either directly or indirectly, are the incoherent $mathrm{e}^{+}mathrm{e}^{-}$ pairs and the particles from $gammagamma ightarrow$ hadron events. The background and radiation levels in the detector have to be estimated, to study if a detector is feasible, that can han...

  9. Sub-MeV solar neutrinos: experimental techniques and background sources

    Energy Technology Data Exchange (ETDEWEB)

    Ianni, A [I.N.F.N., Gran Sasso Laboratory, S.S. 17bis Km 18-910, I-67010 Assergi (AQ) (Italy)

    2006-10-01

    In this paper, we review the main background sources and the experimental techniques used to search for sub-MeV solar neutrinos. Planned and under commission experiments aim to measure sub-MeV solar neutrinos in real time. The search for sub-MeV solar neutrinos will allow us to study both sub-dominant effects to the present interpretation of solar neutrino phenomenology, the so-called large mixing angle (LMA) solution. Moreover this search will offer a unique possibility to test the Solar Standard Model at the level of a few per cent.

  10. Promoting menstrual health among persian adolescent girls from low socioeconomic backgrounds: a quasi-experimental study

    Directory of Open Access Journals (Sweden)

    Fakhri Moloud

    2012-03-01

    Full Text Available Abstract Background Research in the past decade has revealed average to poor menstrual health among many Iranian girls. The present study investigated the effectiveness of a health promotion project on improving menstrual health in adolescent girls in Iran. Methods A quasi-experimental study was conducted to evaluate the effectiveness of the health intervention program. A total of 698 students (study participants and controls in several schools in Mazandaran province, Iran were included. The project comprised 10 two-hour educational sessions. Educational topics included the significance of adolescence, physical and emotional changes during adolescence, pubertal and menstruation health and premenstrual syndrome. A self-administered questionnaire measuring demographic characteristics, behaviors during menstruation, menstrual patterns, sources of information about menstruation and personal health data was administered. The questionnaire was administered to all participating students after the experimental group received the training. Results Among the most significant results was the impact of educational sessions on bathing and genital hygiene. A total of 61.6% in the experimental group compared with 49.3% in the control group engaged in usual bathing during menstruation (p = 0.002. Individual health status was significantly statistically correlated with menstrual health. Attitude towards menstruation was also significantly related to menstrual health. Conclusions The present study confirms that educational interventions, such as the health promotion project in this study, can be quite effective in promoting menstrual health.

  11. Testing the role of genetic background in parallel evolution using the comparative experimental evolution of antibiotic resistance.

    Science.gov (United States)

    Vogwill, Tom; Kojadinovic, Mila; Furió, Victoria; MacLean, R Craig

    2014-12-01

    Parallel evolution is the independent evolution of the same phenotype or genotype in response to the same selection pressure. There are examples of parallel molecular evolution across divergent genetic backgrounds, suggesting that genetic background may not play an important role in determining the outcome of adaptation. Here, we measure the influence of genetic background on phenotypic and molecular adaptation by combining experimental evolution with comparative analysis. We selected for resistance to the antibiotic rifampicin in eight strains of bacteria from the genus Pseudomonas using a short term selection experiment. Adaptation occurred by 47 mutations at conserved sites in rpoB, the target of rifampicin, and due to the high diversity of possible mutations the probability of within-strain parallel evolution was low. The probability of between-strain parallel evolution was only marginally lower, because different strains substituted similar rpoB mutations. In contrast, we found that more than 30% of the phenotypic variation in the growth rate of evolved clones was attributable to among-strain differences. Parallel molecular evolution across strains resulted in divergent phenotypic evolution because rpoB mutations had different effects on growth rate in different strains. This study shows that genetic divergence between strains constrains parallel phenotypic evolution, but had little detectable impact on the molecular basis of adaptation in this system. © The Author 2014. Published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution.

  12. Experimental investigation of plasma relaxation using a compact coaxial magnetized plasma gun in a background plasma

    Science.gov (United States)

    Zhang, Yue; Lynn, Alan; Gilmore, Mark; Hsu, Scott; University of New Mexico Collaboration; Los Alamos National Laboratory Collaboration

    2013-10-01

    A compact coaxial plasma gun is employed for experimental studies of plasma relaxation in a low density background plasma. Experiments are being conducted in the linear HelCat device at UNM. These studies will advance the knowledge of basic plasma physics in the areas of magnetic relaxation and space and astrophysical plasmas, including the evolution of active galactic jets/radio lobes within the intergalactic medium. The gun is powered by a 120pF ignitron-switched capacitor bank which is operated in a range of 5-10 kV and ~100 kA. Multiple diagnostics are employed to investigate plasma relaxation process. Magnetized Argon plasma bubbles with velocities ~1.2Cs and densities ~1020 m-3 have been achieved. Different distinct regimes of operation with qualitatively different dynamics are identified by fast CCD camera images, with the parameter determining the operation regime. Additionally, a B-dot probe array is employed to measure the spatial toroidal and poloidal magnetic flux evolution to identify detached plasma bubble configurations. Experimental data and analysis will be presented.

  13. Uncertainty in techno-economic estimates of cellulosic ethanol production due to experimental measurement uncertainty

    Directory of Open Access Journals (Sweden)

    Vicari Kristin J

    2012-04-01

    Full Text Available Abstract Background Cost-effective production of lignocellulosic biofuels remains a major financial and technical challenge at the industrial scale. A critical tool in biofuels process development is the techno-economic (TE model, which calculates biofuel production costs using a process model and an economic model. The process model solves mass and energy balances for each unit, and the economic model estimates capital and operating costs from the process model based on economic assumptions. The process model inputs include experimental data on the feedstock composition and intermediate product yields for each unit. These experimental yield data are calculated from primary measurements. Uncertainty in these primary measurements is propagated to the calculated yields, to the process model, and ultimately to the economic model. Thus, outputs of the TE model have a minimum uncertainty associated with the uncertainty in the primary measurements. Results We calculate the uncertainty in the Minimum Ethanol Selling Price (MESP estimate for lignocellulosic ethanol production via a biochemical conversion process: dilute sulfuric acid pretreatment of corn stover followed by enzymatic hydrolysis and co-fermentation of the resulting sugars to ethanol. We perform a sensitivity analysis on the TE model and identify the feedstock composition and conversion yields from three unit operations (xylose from pretreatment, glucose from enzymatic hydrolysis, and ethanol from fermentation as the most important variables. The uncertainty in the pretreatment xylose yield arises from multiple measurements, whereas the glucose and ethanol yields from enzymatic hydrolysis and fermentation, respectively, are dominated by a single measurement: the fraction of insoluble solids (fIS in the biomass slurries. Conclusions We calculate a $0.15/gal uncertainty in MESP from the TE model due to uncertainties in primary measurements. This result sets a lower bound on the error bars of

  14. Comparative evaluation of two vaccine candidates against experimental leishmaniasis due to Leishmania major infection in four inbred mouse strains.

    Science.gov (United States)

    Benhnini, Fouad; Chenik, Mehdi; Laouini, Dhafer; Louzir, Hechmi; Cazenave, Pierre André; Dellagi, Koussay

    2009-11-01

    Experimental leishmaniasis in BALB/c and C57BL/6 mice are the most investigated murine models that were used for the preclinical evaluation of Leishmania vaccine candidates. We have previously described two new inbred mouse strains named PWK and MAI issued from feral founders that also support the development of experimental leishmaniasis due to L. major. In this study, we sought to determine whether different mouse inbred strains generate concordant or discordant results when used to evaluate the potential of Leishmania proteins to protect against experimental leishmaniasis. To this end, two Leishmania proteins, namely, LACK (for Leishmania homolog of receptor for activated C kinase) and LmPDI (for L. major protein disulfide isomerase) were compared for their capacity to protect against experimental leishmaniasis in PWK, MAI, BALB/c, and C57BL/6 inbred mouse strains. Our data show that the capacity of Leishmania proteins to confer protection depends on the mouse strain used, stressing the important role played by the genetic background in shaping the immune response against the pathogen. These results may have important implications for the preclinical evaluation of candidate Leishmania vaccines: rather than using a single mouse strain, a panel of different inbred strains of various genetic backgrounds should be tested in parallel. The antigen that confers protection in the larger range of inbred strains may have better chances to be also protective in outbred human populations and should be selected for clinical trials.

  15. Comparative Evaluation of Two Vaccine Candidates against Experimental Leishmaniasis Due to Leishmania major Infection in Four Inbred Mouse Strains▿

    Science.gov (United States)

    Benhnini, Fouad; Chenik, Mehdi; Laouini, Dhafer; Louzir, Hechmi; Cazenave, Pierre André; Dellagi, Koussay

    2009-01-01

    Experimental leishmaniasis in BALB/c and C57BL/6 mice are the most investigated murine models that were used for the preclinical evaluation of Leishmania vaccine candidates. We have previously described two new inbred mouse strains named PWK and MAI issued from feral founders that also support the development of experimental leishmaniasis due to L. major. In this study, we sought to determine whether different mouse inbred strains generate concordant or discordant results when used to evaluate the potential of Leishmania proteins to protect against experimental leishmaniasis. To this end, two Leishmania proteins, namely, LACK (for Leishmania homolog of receptor for activated C kinase) and LmPDI (for L. major protein disulfide isomerase) were compared for their capacity to protect against experimental leishmaniasis in PWK, MAI, BALB/c, and C57BL/6 inbred mouse strains. Our data show that the capacity of Leishmania proteins to confer protection depends on the mouse strain used, stressing the important role played by the genetic background in shaping the immune response against the pathogen. These results may have important implications for the preclinical evaluation of candidate Leishmania vaccines: rather than using a single mouse strain, a panel of different inbred strains of various genetic backgrounds should be tested in parallel. The antigen that confers protection in the larger range of inbred strains may have better chances to be also protective in outbred human populations and should be selected for clinical trials. PMID:19726616

  16. A Theory of the Podkletnov Effect based on General Relativity: Anti-Gravity Force due to the Perturbed Non-Holonomic Background of Space

    Directory of Open Access Journals (Sweden)

    Rabounski D.

    2007-07-01

    Full Text Available We consider the Podkletnov effect — the weight loss of an object located over a superconducting disc in air due to support by an alternating magnetic field. We consider this problem using the mathematical methods of General Relativity. We show via Einstein’s equations and the geodesic equations in a space perturbed by a disc undergoing oscillatory bounces orthogonal to its own plane, that there is no r ˆ ole of superconductivity; the Podkletnov effect is due to the fact that the field of the background space non-holonomity (the basic non-othogonality of time lines to the spatial section, being perturbed by such an oscillating disc produces energy and momentum flow in order to compensate the perturbation in itself. Such a momentum flow is directed above the disc in Podkletnov’s experiment, so it works like negative gravity (anti-gravity. We propose a simple mechanical system which, simulating the Podkletnov effect, is an experimental test of the whole theory. The theory allows for other “anti-gravity devices”, which simulate the Podkletnov effect without use of very costly superconductor technology. Such devices could be applied to be used as a cheap source of new energy, and could have implications to air and space travel.

  17. Impairment due to alcohol, tetrahydrocannabinol, and benzodiazepines in impaired drivers compared to experimental studies.

    Science.gov (United States)

    Høiseth, Gudrun; Berg-Hansen, Grim Otto; Øiestad, Åse Marit L; Bachs, Liliana; Mørland, Jørg

    2017-04-03

    relationship between drug concentration and impairment was seen for both experimental studies and real-life cases. We believe that the present study strengthens the background for using experimental studies to establish fixed concentration limits for drunk and drugged drivers, but experimental studies in an impaired driver population could further expand our knowledge.

  18. Experimental observation of strong mixing due to internal wave focusing over sloping terrain

    NARCIS (Netherlands)

    Swart, A.; Manders, A.; Harlander, U.; Maas, L.R.M.

    2010-01-01

    This paper reports on experimental observation of internal waves that are focused due to a sloping topography. A remarkable mixing of the density field was observed. This result is of importance for the deep ocean, where internal waves are believed to play a role in mixing. The experiments were

  19. Experimental evidence of lateral flow in unsaturated homogeneous isotropic sloping soil due to rainfall

    NARCIS (Netherlands)

    Sinai, G.; Dirksen, C.

    2006-01-01

    This paper describes laboratory experimental evidence for lateral flow in the top layer of unsaturated sloping soil due to rainfall. Water was applied uniformly on horizontal and V-shaped surfaces of fine sand, at rates about 100 times smaller than the saturated hydraulic conductivity. Flow regimes

  20. Experimental investigation of coaxial-gun-formed plasmas injected into a background transverse magnetic field or plasma

    OpenAIRE

    Zhang, Yue; Hsu, Scott C.; Fisher, Dustin M.; Gilmore, Mark; Lynn, Alan G.

    2017-01-01

    Injection of coaxial-gun-formed magnetized plasmas into a background transverse vacuum magnetic field or into a background magnetized plasma has been studied in the helicon-cathode (HelCat) linear plasma device at the University of New Mexico [M. Gilmore et al., J. Plasma Phys.81, 345810104 (2015)]. Magnetized plasma jet launched into a background transverse magnetic field shows emergent kink stabilization of the jet due to the formation of a sheared flow in the jet above the kink-stabilizati...

  1. Experimental Study on Impact Load on a Dam Due to Debris Flow

    Science.gov (United States)

    lwao Miyoshi

    1991-01-01

    When a dam is struck by mud or debris flow, it is put under a great impact load and sometimes is destroyed. To prevent such destruction, it is important to perform basic research about the impact load on a dam due to debris flow. Thus, we have made an experimental study and tried to establish a method to estimate such a impact load on the dam. The experiment was...

  2. Fiber Bragg Grating sensors for structural health monitoring of Tsing Ma bridge: background and experimental observation

    NARCIS (Netherlands)

    Chan, T.H.T.; Yu, L.; Tam, H.Y.; Ni, Y.Q.; Liu, S.Y.; Chung, W.H.; Cheng, L.K.

    2006-01-01

    The rapid expansion of the optical fiber telecommunication industry due to the explosion of the Internet has substantially driven down the cost of optical components, making fiber optic sensors more economically viable. In addition, the rapid development of fiber-optic sensors, particularly the

  3. Air pollution episodes in Stockholm regional background air due to sources in Europe and their effects on human population

    Energy Technology Data Exchange (ETDEWEB)

    Andersson, C. [Swedish Meteorological and Hydrological Inst., Norrkoping (Sweden)], E-mail: camilla.andersson@smhi.se; Joensson, O. [Stockholm Univ. (Sweden). Dept. of Applied Environmental Science; Forsberg, B. [Umea Univ. (Sweden), Occupational and Environmental Medicine; Johansson, C. [Environmental and Health Administration, Stockholm (Sweden)

    2013-09-01

    Using air quality measurements, we categorized air pollution according to source sectors in a rural background environment in southern Sweden based on hourly air-mass backward trajectories during 1997-2010. Concentrations of fine (PM{sub 2.5}) and sum of fine and coarse particulate matter (PM{sub 10}), accumulation mode particle number, black carbon and surface ozone were 4.0, 3.9, 4.5, 6.8 and 1.3 times higher, respectively, in air masses from the southeast as compared with those in air masses from the cleanest sector in the northwest, consistent with air-mass transport over areas with relatively high emissions of primary particulate matter (PM) and secondary PM precursors. The highest ultrafine particle numbers were associated with clean air from the northwest. We estimate that almost 7.8% and 0.6% higher premature human mortality is caused by PM{sub 2.5} and ozone exposure, respectively, when air originates from the southeast as compared with that when air originates from the northwest. Reductions of emissions in eastern Europe would reduce the highest air pollution concentrations and associated health risks. However, since air masses from the southwest are more frequent, emissions in the western part of Europe are more important for annual mean premature mortality. (orig.)

  4. Low Background Techniques And Experimental Challenges For Borexino And Its Nylon Vessels

    CERN Document Server

    Pocar, A P

    2003-01-01

    Borexino is an experiment for low energy (<1 MeV) solar neutrino spectroscopy approaching completion at the underground Gran Sasso laboratories in Italy. It is specifically designed to measure in real time the flux of mono-energetic [/berillium] neutrinos produced by fusion reactions in the Sun. Its 300-ton liquid scintillator target is contained in an 8.5 meter diameter nylon inner vessel (IV) and is surrounded by 1000 tons of buffer fluid. A second, 11.5 meter diameter concentric nylon outer vessel (OV) around the IV serves as a barrier for radon emanated at the periphery of the detector. Borexino requires unprecedented low levels of radioactive impurities to be a success (∼1 background event/day in the central 100-tons of scintillator). The IV, which is in direct contact with the scintillator, also has to meet extremely stringent radioactive and cleanliness requirements. Intrinsic levels ∼10 −12 g/g for U and Th and ∼10−8 g/g for K are needed. The vessels,...

  5. Experimental Facility for Checking the Possibility to Obtain Super-High Temperature Due to Acoustic Cavitation

    CERN Document Server

    Miller, M B; Sobolev, Yu G; Kostenko, B F

    2004-01-01

    An experimental facility developed for checking the possibility to obtain super-high temperature sufficient for thermonuclear reaction D($d, n$)$^{3}$He in an acoustic cavitation is described. The acoustic part of the instrumentation consists of a resonator and a system exciting high amplitude of the acoustic field within the resonator. The cavitation process is controlled with the use of fast neutron pulses. The instrument includes a system of pumping out solute gases from the liquid (acetone enriched with deuterium up to 99{\\%}) without losses of matter. Measuring of the field is based on the calibration procedure including observation of sonoluminescence. The system of detection and identification of D($d, n$)$^{3}$He reaction is based on a scintillation detector of fast neutrons and a system of measuring multiparameter events by the correlation technique with separation of the neutrons from the $\\gamma $-radiation background (pulse shape discrimination).

  6. Histopathological changes due to the effect of selenium in experimental cockerels

    Directory of Open Access Journals (Sweden)

    S.A.A Latheef

    2014-01-01

    Full Text Available Background & objectives: Selenium usually acts as an antioxidant at optimal levels in the body and increased levels are toxic. In this study an attempt was made to evaluate the effect of an optimum dose (0.14 mg of selenium on histopathological changes in experimental hypercholesterolemia in cockerels. Methods: The effect of selenium (0.14 mg was investigated on histopathological changes in four tissues namely liver, kidney, heart, and descending aorta in cockerel animal model. Animals were either fed with stock diet (group C, stock diet with cholesterol (group CH, stock diet with selenium (group Se, stock diet, selenium and cholesterol (group CH+Se for six months. Animals were sacrified and the tissues were isolated and subjected to histopathological study. Results: Xanthochromatic collections in liver were observed in group CH; hydropic degeneration in group Se and lobular disarray, hydropic degeneration and kuppfer cell hyperplasia in group CH+Se were observed. In kidney, mild mononuclear infiltration was observed in interstitium in groups CH, Se and CH+Se. myocyte disruption, and mononuclear infiltration in group CH and c0 H+Se, and disruption of muscle bundles with vascular congestion in group Se were observed. Smooth muscle proliferation in the media of blood vessel was observed in groups CH, Se and CH+Se. Interpretation & conclusions: The results of the present study suggested that the optimum dose of (140 ΅g/day feeding induced atherogenesis by inflammation and smooth muscle proliferation in cockerels with experimentally induced hypercholesterolaemia.

  7. Linezolid in prophylaxis against experimental aortic valve endocarditis due to Streptococcus oralis or Enterococcus faecalis.

    Science.gov (United States)

    Athanassopoulos, George; Pefanis, Angelos; Sakka, Vissaria; Iliopoulos, Dimitrios; Perrea, Despina; Giamarellou, Helen

    2006-02-01

    There are no experimental studies regarding the prophylactic efficacy of linezolid against infective endocarditis. Nonbacterial thrombotic endocarditis of the aortic valve was induced in rabbits by the insertion of a polyethylene catheter. Twenty-four hours later, animals were randomly assigned to a control group, and groups receiving either ampicillin (two doses of 40 mg/kg of body weight each, given intravenously, 2 h apart) or linezolid (a single per os dose of 75 mg/kg). The first dose of ampicillin and the single dose of linezolid were administered 0.5 and 1 h, respectively, prior to the intravenous inoculation of approximately 10(7) CFU of Streptococcus oralis or Enterococcus faecalis. Linezolid peak levels in rabbit serum were similar to the peak serum levels in humans following a 600-mg oral dose of linezolid. Linezolid prevented endocarditis in 87% of S. oralis-challenged rabbits (P faecalis, linezolid prevented endocarditis in 73% (P = 0.003 versus controls; P = 0.049 versus ampicillin). Ampicillin prevented endocarditis due to S. oralis or due to E. faecalis in 47% (P = 0.005 versus controls) and in 30% (P = not significant versus controls) of the challenged animals, respectively. In conclusion, linezolid was effective as prophylaxis against endocarditis caused by a strain of S. oralis and to a lesser degree against that caused by a strain of E. faecalis. Its prophylactic efficacy was superior to that of ampicillin.

  8. Experimental analysis of thread movement in bolted connections due to vibrations

    Science.gov (United States)

    Ramsey, G. ED; Jenkins, Robert C.

    1995-01-01

    This is the final report of research project NAS8-39131 #33 sponsored by NASA's George C. Marshall Space Flight Center (MSFC) and carried out by the Civil Engineering Department of Auburn University (Auburn, Alabama) and personnel of MSFC. The objective of this study was to identify the main design parameters contributing to the loosening of bolts due to vibration and to identify their relative importance and degree of contribution to bolt loosening. Vibration testing was conducted on a shaketable with a controlled-random input in the dynamic testing laboratory of the Structural Test Division of MSFC. Test specimens which contained one test bolt were vibrated for a fixed amount of time and a percentage of pre-load loss was measured. Each specimen tested implemented some combination of eleven design parameters as dictated by the design of experiment methodology employed. The eleven design parameters were: bolt size (diameter), lubrication on bolt, hole tolerance, initial pre-load, nut locking device, grip length, thread pitch, lubrication between mating materials, class of fit, joint configuration, and mass of configuration. These parameters were chosen for this experiment because they are believed to be the design parameters having the greatest impact on bolt loosening. Two values of each design parameter were used and each combination of parameters tested was subjected to two different directions of vibration and two different g-levels of vibration. One replication was made for each test to gain some indication of experimental error and repeatability and to give some degree of statistical credibility to the data, resulting in a total of 96 tests being performed. The results of the investigation indicated that nut locking devices, joint configuration, fastener size, and mass of configuration were significant in bolt loosening due to vibration. The results of this test can be utilized to further research the complex problem of bolt loosening due to vibration.

  9. An experimental investigation of composite floor vibration due to human activities. A case study

    Directory of Open Access Journals (Sweden)

    Yasser G. Mohamed Fahmy

    2012-12-01

    Full Text Available Composite steel floor decks are used in a large variety of constructions with long spans, such as administration and commercial buildings, hotels and bridges. Due to decreased floor mass and longer span lengths, floor vibrations have become an area of concern. Floor decks with low frequencies may be in resonance with the vibrations due to human activities and the resulting acceleration may exceed human comfort levels. The design of slender floor structures, with steel or composite cross sections, is often limited by the serviceability criteria such as deflection limits and vibration behavior, rather than the strength criteria. Control of deflections under AISC specifications requirement is not enough to satisfy the serviceability requirements of the floor systems for vibration. In addition, vibration analysis procedures introduced by AISC design Guide No. 11 are based on regularly-shaped structures and simple boundary conditions. In this paper, a case study for full scale testing of a composite floor system proposed for a tower at Kuwait state that was tested prior to construction. The heel-drop and walking tests are performed on floor systems with and without raised floor respectively. Since heel-drop and walking test results would vary in light of person performance, both tests are carried out three or four times to reduce uncertainty. The fundamental frequencies and damping ratio of the floor system are measured. Comparison of the experimental results with results based on the AISC hand calculations shows that there is no significant difference; therefore the results based on AISC are generally acceptable.

  10. Experimental Research on Compression Properties of Cement Asphalt Mortar due to Drying and Wetting Cycle

    Directory of Open Access Journals (Sweden)

    Ping Wang

    2014-01-01

    Full Text Available Uniaxial compression test of cement asphalt (CA mortar specimens, due to drying and wetting cycle of 0, 2, 4 and 8 times, is carried out by using the electronic universal test machine, with the strain rate ranging from 1 × 10−5 s−1 to 1 × 10−2 s−1. The effects of strain rate and drying and wetting cycle time on the compressive strength, elasticity modulus, and stress-strain full curve are investigated. Experimental results show that the strain-stress full curve of CA mortar is affected obviously by strain rate and drying and wetting cycle time. The compressive strength and elasticity modulus increase with the strain rate under the same drying and wetting cycle time. The compressive strength and elasticity modulus decrease with the increase of drying and wetting cycle time in the same strain rate. The lower the strain rate is, the greater the compressive strength and elasticity modulus of CA mortar decrease. When the strain rate is 1 × 10−5 s−1 and drying and wetting cycle time is 8, the largest reduction of average compressive strength of CA mortar is 40.48%, and the largest reduction of elasticity modulus of CA mortar is 35.51%, and the influence of drying and wetting cycle on the compressive strength of CA mortar is greater than its influence on the elasticity modulus.

  11. Paraquat poisoning: an experimental model of dose-dependent acute lung injury due to surfactant dysfunction

    Directory of Open Access Journals (Sweden)

    M.F.R. Silva

    1998-03-01

    Full Text Available Since the most characteristic feature of paraquat poisoning is lung damage, a prospective controlled study was performed on excised rat lungs in order to estimate the intensity of lesion after different doses. Twenty-five male, 2-3-month-old non-SPF Wistar rats, divided into 5 groups, received paraquat dichloride in a single intraperitoneal injection (0, 1, 5, 25, or 50 mg/kg body weight 24 h before the experiment. Static pressure-volume (PV curves were performed in air- and saline-filled lungs; an estimator of surface tension and tissue works was computed by integrating the area of both curves and reported as work/ml of volume displacement. Paraquat induced a dose-dependent increase of inspiratory surface tension work that reached a significant two-fold order of magnitude for 25 and 50 mg/kg body weight (P<0.05, ANOVA, sparing lung tissue. This kind of lesion was probably due to functional abnormalities of the surfactant system, as was shown by the increase in the hysteresis of the paraquat groups at the highest doses. Hence, paraquat poisoning provides a suitable model of acute lung injury with alveolar instability that can be easily used in experimental protocols of mechanical ventilation

  12. Virulence Differences among Melissococcus plutonius Strains with Different Genetic Backgrounds in Apis mellifera Larvae under an Improved Experimental Condition.

    Science.gov (United States)

    Nakamura, Keiko; Yamazaki, Yuko; Shiraishi, Akiyo; Kobayashi, Sota; Harada, Mariko; Yoshiyama, Mikio; Osaki, Makoto; Okura, Masatoshi; Takamatsu, Daisuke

    2016-09-14

    European foulbrood (EFB) caused by Melissococcus plutonius is an important bacterial disease of honeybee larvae. M. plutonius strains can be grouped into three genetically distinct groups (CC3, CC12 and CC13). Because EFB could not be reproduced in artificially reared honeybee larvae by fastidious strains of CC3 and CC13 previously, we investigated a method to improve experimental conditions using a CC3 strain and found that infection with a potassium-rich diet enhanced proliferation of the fastidious strain in larvae at the early stage of infection, leading to the appearance of clear clinical symptoms. Further comparison of M. plutonius virulence under the conditions revealed that the representative strain of CC12 was extremely virulent and killed all tested bees before pupation, whereas the CC3 strain was less virulent than the CC12 strain, and a part of the infected larvae pupated. In contrast, the tested CC13 strain was avirulent, and as with the non-infected control group, most of the infected brood became adult bees, suggesting differences in the insect-level virulence among M. plutonius strains with different genetic backgrounds. These strains and the improved experimental infection method to evaluate their virulence will be useful tools for further elucidation of the pathogenic mechanisms of EFB.

  13. Studies on Crop Growth Damage due to Ash Fall form Mt. Minamidake of Sakurajima : (1)Experimental Indications of Crop Damage due to Ash Fall

    OpenAIRE

    角, 明夫; 鈴木, 義則; Akio, SUMI; Yoshinori, SUZUKI; 鹿児島大学農学部生物生産学科; 九州大学農学部農業工学科; Department of Agricultural Sciences, Faculty of Agriculture, Kagoshima University; Department of Agricultural Engineering, Faculty of Agriculture, Kyusyu University

    1998-01-01

    The occurrence mechanisms of crop growth damage due to ash fall were examined experimentally. When volcanic ash was mixed into arable soil, the crop growth was reduced with increasing in its amount because of the deterioration in physical and chemical properties of soil. When the normal soil was arranged concentrically around the main root of a crop, the improvement effect by soil admixing could be found on the smaller replacement. The crop growth was also inhibited when volcanic ash accumula...

  14. Photoacoustic Experimental System to Confirm Infrared Absorption Due to Greenhouse Gases

    Science.gov (United States)

    Kaneko, Fumitoshi; Monjushiro, Hideaki; Nishiyama, Masayoshi; Kasai, Toshio; Harris, Harold H.

    2010-01-01

    An experimental system for detecting infrared absorption using the photoacoustic (PA) effect is described. It is aimed for use at high-school level to illustrate the difference in infrared (IR) absorption among the gases contained in the atmosphere in connection with the greenhouse effect. The experimental system can be built with readily…

  15. Experimental Determination of System Outage Probability Due to First-Order and Second-Order PMD

    Science.gov (United States)

    Yaffe, Henry H.; Peterson, Daniel L., Jr.

    2006-11-01

    In this paper, a polarization-mode dispersion (PMD) tolerance testing procedure for transponders and transmission systems is described. This method exploits programmable PMD sources for testing the first- and second-order joint probability density function to estimate the total PMD network outage. Experimental data show that first-order-only PMD testing is insufficient to quantify the tolerance of a transponder and may falsely underestimate network outage.

  16. Live Fast, Die Young: Experimental Evidence of Population Extinction Risk due to Climate Change.

    Directory of Open Access Journals (Sweden)

    Elvire Bestion

    2015-10-01

    Full Text Available Evidence has accumulated in recent decades on the drastic impact of climate change on biodiversity. Warming temperatures have induced changes in species physiology, phenology, and have decreased body size. Such modifications can impact population dynamics and could lead to changes in life cycle and demography. More specifically, conceptual frameworks predict that global warming will severely threaten tropical ectotherms while temperate ectotherms should resist or even benefit from higher temperatures. However, experimental studies measuring the impacts of future warming trends on temperate ectotherms' life cycle and population persistence are lacking. Here we investigate the impacts of future climates on a model vertebrate ectotherm species using a large-scale warming experiment. We manipulated climatic conditions in 18 seminatural populations over two years to obtain a present climate treatment and a warm climate treatment matching IPCC predictions for future climate. Warmer temperatures caused a faster body growth, an earlier reproductive onset, and an increased voltinism, leading to a highly accelerated life cycle but also to a decrease in adult survival. A matrix population model predicts that warm climate populations in our experiment should go extinct in around 20 y. Comparing our experimental climatic conditions to conditions encountered by populations across Europe, we suggest that warming climates should threaten a significant number of populations at the southern range of the distribution. Our findings stress the importance of experimental approaches on the entire life cycle to more accurately predict population and species persistence in future climates.

  17. Experimental study of geo-acoustic inversion uncertainty due to ocean sound-speed fluctuations.

    NARCIS (Netherlands)

    Siderius, M.; Nielsen, P.L.; Sellschopp, J.; Snellen, M.; Simons, D.G.

    2001-01-01

    Acoustic data measured in the ocean fluctuate due to the complex time-varying properties of the channel. When measured data are used for model-based, geo-acoustic inversion, how do acoustic fluctuations impact estimates for the seabed properties? In May 1999 SACLANT Undersea Research Center and

  18. Experimental investigation of zero phase shift effects for Coriolis flowmeters due to pipe imperfections

    DEFF Research Database (Denmark)

    Enz, Stephanie; Thomsen, Jon Juel; Neumeyer, Stefan

    2011-01-01

    Theoretical investigations of a single, straight, vibrating, fluid-conveying pipe have resulted in simple analytical expressions for the approximate prediction of the spatial shift in vibration phase. The expressions have lead to hypotheses for real Coriolis flowmeters (CFMs). To test these......, the flexural vibrations of two bent, parallel, non-fluid-conveying pipes are studied experimentally, employing an industrial CFM. Special attention has been paid on the phase shift in the case of zero mass flow, i.e. the zero shift, caused by various imperfections to the ‘‘perfect’’ CFM, i.e. non-uniform pipe...

  19. White matter injury due to experimental chronic cerebral hypoperfusion is associated with C5 deposition.

    Science.gov (United States)

    Liu, Qinghai; He, Shuhan; Groysman, Leonid; Shaked, David; Russin, Jonathan; Scotton, Thomas C; Cen, Steven; Mack, William J

    2013-01-01

    The C5 complement protein is a potent inflammatory mediator that has been implicated in the pathogenesis of both stroke and neurodegenerative disease. Microvascular failure is proposed as a potential mechanism of injury. Along these lines, this investigation examines the role of C5 in the setting of chronic cerebral hypoperfusion. Following experimental bilateral carotid artery stenosis, C5 protein deposition increases in the corpus callosum over thirty days (pC5 levels do not appear to differ between bilateral carotid artery stenosis and sham-operated mice, implicating a local cerebral process. Following bilateral carotid artery stenosis, C5 deficient mice demonstrate decreased white matter ischemia in the corpus callosum when compared to C5 sufficient controls (pC5 deficient mice exhibit fewer reactive astrocytes and microglia (pC5 complement protein may play a critical role in mediating white matter injury through inflammation in the setting of chronic cerebral hypoperfusion.

  20. Experimental and Numerical Analysis of Bridge Response due to Modular Combination Vehicle Systems

    DEFF Research Database (Denmark)

    Kirkegaard, Poul Henning; Bang, R.

    2004-01-01

    paper investigates the dynamic amplification of a minor Danish highway bridge due to passage of such modular combination vehicle systems. A simulation model for a typical Danish highway bridge and the two different vehicles is established. The two different vehicles are a standard 48.8 ton articulated...... vehicle and a 60 ton vehicle consisting of a lorry and semi-trailer carried by a dolly. The dynamic parameters of the vehicles and the modal parameters of the bridge are estimated from measurements obtained for different passage situations of the two vehicles. Results show a good agreement between...... simulated and measured bridge acceleration response and dynamic amplification factors....

  1. Inactivation of pulmonary surfactant due to serum-inhibited adsorption and reversal by hydrophilic polymers: experimental

    DEFF Research Database (Denmark)

    Taeusch, H William; de la Serna, Jorge Bernardino; Perez-Gil, Jesus

    2005-01-01

    increases in pi did not occur when surfactants were applied to subphases containing serum. Components of serum are surface active and adsorb reversibly to the interface increasing pi up to a concentration-dependent saturation value, pi(max). When surfactants were applied to subphases containing serum......The rate of change of surface pressure, pi, in a Langmuir trough following the deposition of surfactant suspensions on subphases containing serum, with or without polymers, is used to model a likely cause of surfactant inactivation in vivo: inhibition of surfactant adsorption due to competitive...... adsorption of surface active serum proteins. Aqueous suspensions of native porcine surfactant, organic extracts of native surfactant, and the clinical surfactants Curosurf, Infasurf, and Survanta spread on buffered subphases increase the surface pressure, pi, to approximately 40 mN/m within 2 min...

  2. Aspirin plus ticlopidine prevented experimental endocarditis due to Enterococcus faecalis and Streptococcus gallolyticus.

    Science.gov (United States)

    Veloso, Tiago Rafael; Oechslin, Frank; Que, Yok-Ai; Moreillon, Philippe; Entenza, José Manuel; Mancini, Stefano

    2015-11-01

    Enterococcus faecalis and Streptococcus gallolyticus cause infective endocarditis (IE), which can originate from the continuous release or translocation of low bacterial numbers into the bloodstream. In this context, IE cannot be prevented with antibiotics. We previously demonstrated that aspirin plus ticlopidine protected rats from IE due to S. gordonii and Staphylococcus aureus. Here we showed that aspirin plus ticlopidine significantly reduced vegetation weight and protected 73 and 64% rats (P faecalis and S. gallolyticus, respectively. These results further support the potential use of aspirin plus ticlopidine for a global prevention of IE in high-risk patients. © FEMS 2015. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  3. Effect of therapeutic chemical agents in vitro and on experimental meningoencephalitis due to Naegleria fowleri.

    Science.gov (United States)

    Kim, Jong-Hyun; Jung, Suk-Yul; Lee, Yang-Jin; Song, Kyoung-Ju; Kwon, Daeho; Kim, Kyongmin; Park, Sun; Im, Kyung-Il; Shin, Ho-Joon

    2008-11-01

    Naegleria fowleri is a ubiquitous, pathogenic free-living amoeba; it is the most virulent Naegleria species and causes primary amoebic meningoencephalitis (PAME) in laboratory animals and humans. Although amphotericin B is currently the only agent available for the treatment of PAME, it is a very toxic antibiotic and may cause many adverse effects on other organs. In order to find other potentially therapeutic agents for N. fowleri infection, the present study was undertaken to evaluate the in vitro and in vivo efficacies of miltefosine and chlorpromazine against pathogenic N. fowleri. The result showed that the growth of the amoeba was effectively inhibited by treatment with amphotericin B, miltefosine, and chlorpromazine. When N. fowleri trophozoites were treated with amphotericin B, miltefosine, and chlorpromazine, the MICs of the drug were 0.78, 25, and 12.5 microg/ml, respectively, on day 2. In experimental meningoencephalitis of mice that is caused by N. fowleri, the survival rates of mice treated with amphotericin B, miltefosine, and chlorpromazine were 40, 55, and 75%, respectively, during 1 month. The average mean time to death for the amphotericin B, miltefosine, and chlorpromazine treatments was 17.9 days. In this study, the effect of drugs was found to be optimal when 20 mg/kg was administered three times on days 3, 7, and 11. Finally, chlorpromazine had the best therapeutic activity against N. fowleri in vitro and in vivo. Therefore, it may be a more useful therapeutic agent for the treatment of PAME than amphotericin B.

  4. A PHYSIOLOGICAL STUDY OF EXPERIMENTAL NEPHRITIS DUE TO BACTERIAL POISONS AND CYTOTOXIC SERA.

    Science.gov (United States)

    Pearce, R M; Eisenbrey, A B

    1911-09-01

    The physiological study of experimental nephritis caused by poisons of bacterial origin demonstrates that the poisons may produce types of nephritis in which either vascular or tubular changes predominate. Diphtheria toxin produces a nephritis which in its late stage is of the vascular type, but in its early stage is distinctly tubular. Tuberculin and mallein uniformly cause lesions of the tubular type, which do not pass into the vascular type. Nephrotoxic and hemolytic immune sera cause changes in the kidneys which by physiological methods of observation present no evidence of vascular injury, but which are anatomically characterized by exudative glomerular lesions of moderate severity. This discrepancy between the results of anatomical and physiological study indicates that a lesion of the membrane controlling the passage of fluids may occur without alteration in the power of the vessels to contract and dilate. This fact is shown clearly by the lesion caused by hemolytic immune serum, which is in sharp contrast to the lesion caused by diphtheria toxin, since the latter substance not only alters the permeability of the membranes but also influences markedly the power of the vessels to contract and dilate. It is necessary therefore if the term "vascular" is used in its broadest sense, to recognize three types of vascular nephritis: (1) one in which little or no anatomical evidence of vascular injury is found, but in which physiological methods show profound vascular changes, as in arsenical nephritis; (2) one in which anatomical evidence of vascular (exudative) injury is prominent, but in which the physiological tests are negative, as in nephritis caused by a hemolytic immune serum; and (3) one in which both anatomical and physiological changes are prominent, as in diphtheria toxin nephritis.

  5. Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background

    Science.gov (United States)

    Rajkumar, D. S. R.; Faitelson, A. V.; Gudyrev, O. S.; Dubrovin, G. M.; Pokrovski, M. V.; Ivanov, A. V.

    2013-01-01

    In the experiment on the white Wistar female rats (222 animals), the osteoprotective effect of enalapril and losartan was studied on experimental models of osteoporosis and osteoporotic fractures. It was revealed that in rats after ovariectomy, the endothelial dysfunction of microcirculation vessels of osteal tissue develops, resulting in occurrence of osteoporosis and delay of consolidation of experimental fractures. Enalapril and losartan prevented the reduction of microcirculation in bone, which was reflected in slowing the thinning of bone trabeculae and in preventing the occurrence of these microfractures, as well as increasing quality of experimental fractures healing. PMID:23401845

  6. Comparative Evaluation of Enalapril and Losartan in Pharmacological Correction of Experimental Osteoporosis and Fractures of Its Background

    Directory of Open Access Journals (Sweden)

    D. S. R. Rajkumar

    2013-01-01

    Full Text Available In the experiment on the white Wistar female rats (222 animals, the osteoprotective effect of enalapril and losartan was studied on experimental models of osteoporosis and osteoporotic fractures. It was revealed that in rats after ovariectomy, the endothelial dysfunction of microcirculation vessels of osteal tissue develops, resulting in occurrence of osteoporosis and delay of consolidation of experimental fractures. Enalapril and losartan prevented the reduction of microcirculation in bone, which was reflected in slowing the thinning of bone trabeculae and in preventing the occurrence of these microfractures, as well as increasing quality of experimental fractures healing.

  7. Experimental Investigation of the Corona Discharge in Electrical Transmission due to AC/DC Electric Fields

    Directory of Open Access Journals (Sweden)

    Fuangpian Phanupong

    2016-01-01

    Full Text Available Nowadays, using of High Voltage Direct Current (HVDC transmission to maximize the transmission efficiency, bulk power transmission, connection of renewable power source from wind farm to the grid is of prime concern for the utility. However, due to the high electric field stress from Direct Current (DC line, the corona discharge can easily be occurred at the conductor surface leading to transmission loss. Therefore, the polarity effect of DC lines on corona inception and breakdown voltage should be investigated. In this work, the effect of DC polarity and Alternating Current (AC field stress on corona inception voltage and corona discharge is investigated on various test objects, such as High Voltage (HV needle, needle at ground plane, internal defect, surface discharge, underground cable without cable termination, cable termination with simulated defect and bare overhead conductor. The corona discharge is measured by partial discharge measurement device with high-frequency current transformer. Finally, the relationship between supply voltage and discharge intensity on each DC polarity and AC field stress can be successfully determined.

  8. Experimental study on malfunction of pacemakers due to exposure to different external magnetic fields.

    Science.gov (United States)

    Tiikkaja, Maria; Alanko, Tommi; Lindholm, Harri; Hietanen, Maila; Hartikainen, Juha; Toivonen, Lauri

    2012-06-01

    Cardiac pacemaker malfunction due to exposure to magnetic fields may cause serious problems in some work environments for workers having cardiac pacemakers. The aim of this study was to find the magnetic field interference thresholds for several commonly used pacemaker models. We investigated 16 pacemakers from three different manufacturers with the frequency range of 2 to 1,000 Hz, using sinusoidal, pulse, ramp, and square waveforms. The magnetic fields were produced by a computer-controlled Helmholtz coil system. Pacemaker malfunction occurred in six of 16 pacemakers. Interaction developed almost immediately after high-intensity magnetic field exposure started. With each waveform, at least two pacemakers exhibited interference. In most exposure settings, there was no interference at magnetic field levels below the international occupational safety limits. Nevertheless, some frequencies using ramp or square waveforms interfered with pacemakers even at levels below public exposure limits. The occurrence of interference depended greatly on the waveform, frequency, magnetic field intensity, and the sensing configuration of the pacemaker. Unipolar configurations were more susceptible for interference than the bipolar ones. In addition, magnetic fields perpendicular to the pacemaker loops were more likely to cause interference than parallel fields. There is a need for further investigations on pacemaker interference caused by different external magnetic fields to ensure safe working environment to workers with a pacemaker.

  9. Experimental observations of turbulent mixing due to Kelvin-Helmholtz instability on the OMEGA Laser Facility

    Energy Technology Data Exchange (ETDEWEB)

    Smalyuk, V. A.; Hansen, J. F.; Hurricane, O. A.; Langstaff, G.; Martinez, D.; Park, H.-S.; Raman, K.; Remington, B. A.; Robey, H. F.; Schilling, O.; Wallace, R. [Lawrence Livermore National Laboratory, Livermore, California 94551 (United States); Elbaz, Y.; Shimony, A.; Shvarts, D. [Physics Department, Nuclear Research Center Negev, Beer-Sheva (Israel); Physics Department, Ben-Gurion University, Beer-Sheva (Israel); Di Stefano, C.; Drake, R. P.; Marion, D.; Krauland, C. M.; Kuranz, C. C. [Department of Atmospheric, Oceanic, and Space Sciences, University of Michigan, Ann Arbor, Michigan 48109 (United States)

    2012-09-15

    Shear-flow, Kelvin-Helmholtz (KH) turbulent mixing experiments were performed on the OMEGA Laser Facility [Boehly et al., Opt. Commun. 133, 495 (1997)] in which laser-driven shock waves propagated through a low-density plastic foam placed on top of a higher-density plastic foil. The plastic foil was comprised a thin iodine-doped plastic tracer layer bonded on each side to an undoped density-matched polyamide-imide plastic. Behind the shock front, lower-density foam plasma flowed over the higher-density plastic plasma, such that the interface between the foam and plastic was KH unstable. The initial perturbations consisted of pre-imposed, sinusoidal 2D perturbations, and broadband 3D perturbations due to surface roughness at the interface between the plastic and foam. KH instability growth was measured using side-on radiography with a point-projection 5-keV vanadium backlighter. Time-integrated images were captured on D-8 x-ray film. Spatial density profiles of iodine-doped plastic mixed with foam were inferred using x-ray radiographs. The mixing layer ensuing from the KH instability with layer width up to {approx}100 {mu}m was observed at a location {approx}1 mm behind the shock front. The measured mixing layer width was in good agreement with predictions based on a simple self-similar model of KH instability growth using an estimate of the shear velocity obtained from numerical simulations of the experiments.

  10. Experimental study of the atmospheric neutrino backgrounds for proton decay to positron and neutral pion searches in water Cherenkov detectors

    CERN Document Server

    Mine, S; Andringa, S; Aoki, S; Argyriades, J; Asakura, K; Ashie, R; Berghaus, F; Berns, H; Bhang, H; Blondel, A; Borghi, S; Bouchez, J; Burguet-Castell, J; Casper, D; Catala, J; Cavata, C; Cervera-Villanueva, Anselmo; Chen, S M; Cho, K O; Choi, J H; Dore, U; Espinal, X; Fechner, M; Fernández, E; Fujii, Y; Fukuda, Y; Gomez-Cadenas, J; Gran, R; Hara, T; Hasegawa, M; Hasegawa, T; Hayato, Y; Helmer, R L; Hiraide, K; Hosaka, J; Ichikawa, A K; Iinuma, M; Ikeda, A; Ishida, T; Ishihara, K; Ishii, T; Ishitsuka, M; Itow, Y; Iwashita, T; Jang, H I; Jeon, E J; Jeong, I S; Joo, K K; Jover, G; Jung, C K; Kajita, T; Kameda, J; Kaneyuki, K; Kato, I; Kearns, E; Kim, C O; Khabibullin, M; Khotjantsev, A; Kielczewska, D; Kim, J Y; Kim, S B; Kitching, P; Kobayashi, K; Kobayashi, T; Konaka, A; Koshio, Y; Kropp, W; Kudenko, Yu; Kuno, Y; Kurimoto, Y; Kutter, T; Learned, J; Likhoded, S; Lim, I T; Loverre, P F; Ludovici, L; Maesaka, H; Mallet, J; Mariani, C; Matsuno, S; Matveev, V; McConnel, K; McGrew, C; Mikheyev, S; Minamino, A; Mineev, O; Mitsuda, C; Miura, M; Moriguchi, Y; Moriyama, S; Nakadaira, T; Nakahata, M; Nakamura, K; Nakano, I; Nakaya, T; Nakayama, S; Namba, T; Nambu, R; Nawang, S; Nishikawa, K; Nitta, K; Nova, F; Novella, P; Obayashi, Y; Okada, A; Okumura, K; Oser, S M; Oyama, Y; Pac, M Y; Pierre, F; Rodríguez, A; Saji, C; Sakuda, M; Sánchez, F; Scholberg, K; Schroeter, R; Sekiguchi, M; Shiozawa, M; Shiraishi, K; Sitjes, G; Smy, M; Sobel, H; Sorel, M; Stone, J; Sulak, L; Suzuki, A; Suzuki, Y; Tada, M; Takahashi, T; Takenaga, Y; Takeuchi, Y; Taki, K; Takubo, Y; Tamura, N; Tanaka, M; Terri, R; T'Jampens, S; Tornero-Lopez, A; Totsuka, Y; Vagins, M; Whitehead, L; Walter, C W; Wang, W; Wilkes, R J; Yamada, S; Yamada, Y; Yamamoto, S; Yanagisawa, C; Yershov, N; Yokoyama, H; Yokoyama, M; Yoo, J; Yoshida, M; Zalipska, J

    2008-01-01

    The atmospheric neutrino background for proton decay to positron and neutral pion in ring imaging water Cherenkov detectors is studied with an artificial accelerator neutrino beam for the first time. In total, about 314,000 neutrino events corresponding to about 10 megaton-years of atmospheric neutrino interactions were collected by a 1,000 ton water Cherenkov detector (KT). The KT charged-current single neutral pion production data are well reproduced by simulation programs of neutrino and secondary hadronic interactions used in the Super-Kamiokande (SK) proton decay search. The obtained proton to positron and neutral pion background rate by the KT data for SK from the atmospheric neutrinos whose energies are below 3 GeV is about two per megaton-year. This result is also relevant to possible future, megaton-scale water Cherenkov detectors.

  11. Respiratory syncytial virus-induced acute and chronic airway disease is independent of genetic background: An experimental murine model

    Directory of Open Access Journals (Sweden)

    Ramilo Octavio

    2005-05-01

    Full Text Available Abstract Background Respiratory syncytial virus (RSV is the leading respiratory viral pathogen in young children worldwide. RSV disease is associated with acute airway obstruction (AO, long-term airway hyperresponsiveness (AHR, and chronic lung inflammation. Using two different mouse strains, this study was designed to determine whether RSV disease patterns are host-dependent. C57BL/6 and BALB/c mice were inoculated with RSV and followed for 77 days. RSV loads were measured by plaque assay and polymerase chain reaction (PCR in bronchoalveolar lavage (BAL and whole lung samples; cytokines were measured in BAL samples. Lung inflammation was evaluated with a histopathologic score (HPS, and AO and AHR were determined by plethysmography. Results Viral load dynamics, histopathologic score (HPS, cytokine concentrations, AO and long-term AHR were similar in both strains of RSV-infected mice, although RSV-infected C57BL/6 mice developed significantly greater AO compared with RSV-infected BALB/c mice on day 5. PCR detected RSV RNA in BAL samples of RSV infected mice until day 42, and in whole lung samples through day 77. BAL concentrations of cytokines TNF-α, IFN-γ, and chemokines MIG, RANTES and MIP-1α were significantly elevated in both strains of RSV-infected mice compared with their respective controls. Viral load measured by PCR significantly correlated with disease severity on days 14 and 21. Conclusion RSV-induced acute and chronic airway disease is independent of genetic background.

  12. Experimental investigation in plasma relaxation by using a compact coaxial magnetized plasma gun in a background plasma

    Science.gov (United States)

    Zhang, Yue; Lynn, Alan; Gilmore, Mark; Hsu, Scott

    2012-10-01

    A compact coaxial plasma gun is employed for experimental studies of plasma relaxation process being conducted in the HELCAT device at UNM. These studies will advance the knowledge of basic plasma physics in the areas of magnetic relaxation and space and astrophysical plasmas, including the evolution of active galactic jets/radio lobes. The gun is powered by a 120pF ignitron-switched capacitor bank which is operated in a range of 5 - 10kV. Multiple diagnostics are employed to investigate plasma relaxation process. Magnetized Argon plasma bubbles with velocities 1.2Cs and densities 10e20 m-3 have been achieved. Different distinct regimes of operation with qualitatively different dynamics are identified by fast CCD camera images, with the parameter lambda determining the operation regime. Additionally, a B-dot probe array is employed to measure the spatial toroidal and poloidal magnetic flux evolution to identify detached plasma bubble configurations. Experimental data and analysis will be presented.

  13. Experimental bounds on. beta beta. -decay, cold dark matter and solar axions with an ultralow background Ge detector

    Energy Technology Data Exchange (ETDEWEB)

    Avignone, F.T. III; Ahlen, S.P.; Brodzinski, R.L.; Dimopolous, S.; Drukier, A.K.; Gelmini, G.; Lynn, B.W.; Miley, H.S.; Reeves, J.H.; Spergel, D.N.

    1986-10-08

    The PNL/USC ultralow background prototype Ge detector in the Homestake goldmine is being applied to searches for 0 nu ..beta beta..-decay, dark matter candidates and solar axions. An upper bound of 2.2 eV has been placed on the Majorana mass of the electron neutrino. The low energy data exclude particles with spin independent Z/sup 0/ exchange interactions having masses between 20 GeV and 5 TeV as significant contributors to the cold dark matter of the halo of our galaxy. The existence of stable Dirac neutrinos more massive than 20 GeV is also excluded except for a narrow region around the Z/sup 0/ resonance. Finally, Dine-Fischler-Srednicki (DFS) axion models with F/2x'/sub e/ less than or equal to 0.5 x 10/sup 7/ GeV are ruled out by the maximum count rate attributable to solar axions. 36 refs., 11 figs.

  14. Center of Pressure Displacement of Standing Posture during Rapid Movements Is Reorganised Due to Experimental Lower Extremity Muscle Pain.

    Directory of Open Access Journals (Sweden)

    Shinichiro Shiozawa

    Full Text Available Postural control during rapid movements may be impaired due to musculoskeletal pain. The purpose of this study was to investigate the effect of experimental knee-related muscle pain on the center of pressure (CoP displacement in a reaction time task condition.Nine healthy males performed two reaction time tasks (dominant side shoulder flexion and bilateral heel lift before, during, and after experimental pain induced in the dominant side vastus medialis or the tibialis anterior muscles by hypertonic saline injections. The CoP displacement was extracted from the ipsilateral and contralateral side by two force plates and the net CoP displacement was calculated.Compared with non-painful sessions, tibialis anterior muscle pain during the peak and peak-to-peak displacement for the CoP during anticipatory postural adjustments (APAs of the shoulder task reduced the peak-to-peak displacement of the net CoP in the medial-lateral direction (P<0.05. Tibialis anterior and vastus medialis muscle pain during shoulder flexion task reduced the anterior-posterior peak-to-peak displacement in the ipsilateral side (P<0.05.The central nervous system in healthy individuals was sufficiently robust in maintaining the APA characteristics during pain, although the displacement of net and ipsilateral CoP in the medial-lateral and anterior-posterior directions during unilateral fast shoulder movement was altered.

  15. Efficacy of trovafloxacin, a new quinolone antibiotic, in experimental staphylococcal endocarditis due to oxacillin-resistant strains.

    Science.gov (United States)

    Bayer, A S; Li, C; Ing, M

    1998-07-01

    Therapeutic options for severe infections caused by strains of oxacillin-resistant Staphylococcus aureus (ORSA) and coagulase-negative staphylococci (ORSE) are very limited. With the increasing resistance of such strains to aminoglycosides, rifampin, and currently available quinolone agents, as well as the recent documentation of increasing resistance of ORSA to vancomycin (VANCO), new treatment alternatives are imperative. The in vivo efficacy of trovafloxacin (TROVA), a new quinolone agent with excellent antistaphylococcal activity in vitro, against experimental endocarditis (IE) due to beta-lactamase-producing ORSA and ORSE strains (ORSA and ORSE IE) was evaluated. TROVA (25 mg/kg of body weight intravenously [i.v.] twice daily [b.i.d]) was compared to VANCO (20 mg/kg i.v. b.i.d.) and two regimens of ampicillin-sulbactam (AMP-SUL; 200 mg/kg intramuscularly [i.m.] three times a day [t.i.d.] and 20 mg/kg i.m. b.i.d.), with all agents given for 3 or 6 days. AMP-SUL was included as a comparative treatment regimen because of its proven efficacy against experimental ORSA and ORSE IE. For both ORSA and ORSE IE, TROVA, AMP-SUL, and VANCO each reduced staphylococcal densities in vegetations compared to untreated controls (P TROVA was the most rapidly bactericidal agent--although not to a statistically significant degree--correlating with its superior bactericidal effect in vitro compared to those of VANCO and AMP-SUL.

  16. Hardening of particle/oil/water suspensions due to capillary bridges: Experimental yield stress and theoretical interpretation.

    Science.gov (United States)

    Danov, Krassimir D; Georgiev, Mihail T; Kralchevsky, Peter A; Radulova, Gergana M; Gurkov, Theodor D; Stoyanov, Simeon D; Pelan, Eddie G

    2018-01-01

    Suspensions of colloid particles possess the remarkable property to solidify upon the addition of minimal amount of a second liquid that preferentially wets the particles. The hardening is due to the formation of capillary bridges (pendular rings), which connect the particles. Here, we review works on the mechanical properties of such suspensions and related works on the capillary-bridge force, and present new rheological data for the weakly studied concentration range 30-55 vol% particles. The mechanical strength of the solidified capillary suspensions, characterized by the yield stress Y, is measured at the elastic limit for various volume fractions of the particles and the preferentially wetting liquid. A quantitative theoretical model is developed, which relates Y with the maximum of the capillary-bridge force, projected on the shear plane. A semi-empirical expression for the mean number of capillary bridges per particle is proposed. The model agrees very well with the experimental data and gives a quantitative description of the yield stress, which increases with the rise of interfacial tension and with the volume fractions of particles and capillary bridges, but decreases with the rise of particle radius and contact angle. The quantitative description of capillary force is based on the exact theory and numerical calculation of the capillary bridge profile at various bridge volumes and contact angles. An analytical formula for Y is also derived. The comparison of the theoretical and experimental strain at the elastic limit reveals that the fluidization of the capillary suspension takes place only in a deformation zone of thickness up to several hundred particle diameters, which is adjacent to the rheometer's mobile plate. The reported experimental results refer to water-continuous suspension with hydrophobic particles and oily capillary bridges. The comparison of data for bridges from soybean oil and hexadecane surprisingly indicate that the yield strength is

  17. The protective effect of L-carnitine against hippocampal damage due to experimental formaldehyde intoxication in rats.

    Science.gov (United States)

    Ozmen, E; Ozsoy, S Y; Donmez, N; Ozsoy, B; Yumuşak, N

    2014-07-01

    We investigated the protective effects of L-carnitine on hippocampus tissue damage in rats during experimental formaldehyde (FA) intoxication. Male Wistar albino rats were assigned into four groups: (1) control (C), (2) formaldehyde (FA), (3) formaldehyde + 0.5 g/kg of L-carnitine (FA + 0.5 LC) (4) formaldehyde + 1 g/kg L-carnitine (FA + 1 LC). At the end of the 14 day trial period, animals were sacrificed by decapitation under anesthesia. The hippocampus tissue samples were extracted to measure MDA, GSH and SOD activity. Neuronal degeneration was assessed based on histopathological (hematoxylin and eosin) and immunohistochemical (anti-ubiquitin) examination. To detect oxidative stress, specimens were reacted with anti-Cu/Zn-SOD antibody. After administering L-carnitine with FA to the animals, the activities of SOD and GSH increased, but the levels of MDA decreased in hippocampus tissue. Neuronal degeneration was observed in the FA group. L-carnitine administration reduced neuronal degeneration and histological structure was similar to controls. After FA application, degenerated hippocampus neurons were stained with anti-ubiquitin and Cu/Zn-SOD antibodies; weakly positive staining was observed in L- carnitine-treated groups. L-carnitine may be useful for preventing oxidative damage in the hippocampus tissue due to formaldehyde intoxication.

  18. Light and Nutrient Dependent Responses in Secondary Metabolites of Plantago lanceolata Offspring Are Due to Phenotypic Plasticity in Experimental Grasslands.

    Directory of Open Access Journals (Sweden)

    Annegret Miehe-Steier

    Full Text Available A few studies in the past have shown that plant diversity in terms of species richness and functional composition can modify plant defense chemistry. However, it is not yet clear to what extent genetic differentiation of plant chemotypes or phenotypic plasticity in response to diversity-induced variation in growth conditions or a combination of both is responsible for this pattern. We collected seed families of ribwort plantain (Plantago lanceolata from six-year old experimental grasslands of varying plant diversity (Jena Experiment. The offspring of these seed families was grown under standardized conditions with two levels of light and nutrients. The iridoid glycosides, catalpol and aucubin, and verbascoside, a caffeoyl phenylethanoid glycoside, were measured in roots and shoots. Although offspring of different seed families differed in the tissue concentrations of defensive metabolites, plant diversity in the mothers' environment did not explain the variation in the measured defensive metabolites of P. lanceolata offspring. However secondary metabolite levels in roots and shoots were strongly affected by light and nutrient availability. Highest concentrations of iridoid glycosides and verbascoside were found under high light conditions, and nutrient availability had positive effects on iridoid glycoside concentrations in plants grown under high light conditions. However, verbascoside concentrations decreased under high levels of nutrients irrespective of light. The data from our greenhouse study show that phenotypic plasticity in response to environmental variation rather than genetic differentiation in response to plant community diversity is responsible for variation in secondary metabolite concentrations of P. lanceolata in the six-year old communities of the grassland biodiversity experiment. Due to its large phenotypic plasticity P. lanceolata has the potential for a fast and efficient adjustment to varying environmental conditions in

  19. Light and Nutrient Dependent Responses in Secondary Metabolites of Plantago lanceolata Offspring Are Due to Phenotypic Plasticity in Experimental Grasslands

    Science.gov (United States)

    Miehe-Steier, Annegret; Roscher, Christiane; Reichelt, Michael; Gershenzon, Jonathan; Unsicker, Sybille B.

    2015-01-01

    A few studies in the past have shown that plant diversity in terms of species richness and functional composition can modify plant defense chemistry. However, it is not yet clear to what extent genetic differentiation of plant chemotypes or phenotypic plasticity in response to diversity-induced variation in growth conditions or a combination of both is responsible for this pattern. We collected seed families of ribwort plantain (Plantago lanceolata) from six-year old experimental grasslands of varying plant diversity (Jena Experiment). The offspring of these seed families was grown under standardized conditions with two levels of light and nutrients. The iridoid glycosides, catalpol and aucubin, and verbascoside, a caffeoyl phenylethanoid glycoside, were measured in roots and shoots. Although offspring of different seed families differed in the tissue concentrations of defensive metabolites, plant diversity in the mothers' environment did not explain the variation in the measured defensive metabolites of P. lanceolata offspring. However secondary metabolite levels in roots and shoots were strongly affected by light and nutrient availability. Highest concentrations of iridoid glycosides and verbascoside were found under high light conditions, and nutrient availability had positive effects on iridoid glycoside concentrations in plants grown under high light conditions. However, verbascoside concentrations decreased under high levels of nutrients irrespective of light. The data from our greenhouse study show that phenotypic plasticity in response to environmental variation rather than genetic differentiation in response to plant community diversity is responsible for variation in secondary metabolite concentrations of P. lanceolata in the six-year old communities of the grassland biodiversity experiment. Due to its large phenotypic plasticity P. lanceolata has the potential for a fast and efficient adjustment to varying environmental conditions in plant communities of

  20. Genetic background can result in a marked or minimal effect of gene knockout (GPR55 and CB2 receptor in experimental autoimmune encephalomyelitis models of multiple sclerosis.

    Directory of Open Access Journals (Sweden)

    Sofia Sisay

    Full Text Available Endocannabinoids and some phytocannabinoids bind to CB1 and CB2 cannabinoid receptors, transient receptor potential vanilloid one (TRPV1 receptor and the orphan G protein receptor fifty-five (GPR55. Studies using C57BL/10 and C57BL/6 (Cnr2 (tm1Zim CB2 cannabinoid receptor knockout mice have demonstrated an immune-augmenting effect in experimental autoimmune encephalomyelitis (EAE models of multiple sclerosis. However, other EAE studies in Biozzi ABH mice often failed to show any treatment effect of either CB2 receptor agonism or antagonism on inhibition of T cell autoimmunity. The influence of genetic background on the induction of EAE in endocannabinoid system-related gene knockout mice was examined. It was found that C57BL/6.GPR55 knockout mice developed less severe disease, notably in female mice, following active induction with myelin oligodendrocyte glycoprotein 35-55 peptide. In contrast C57BL/6.CB2 (Cnr2 (Dgen receptor knockout mice developed augmented severity of disease consistent with the genetically and pharmacologically-distinct, Cnr2 (tm1Zim mice. However, when the knockout gene was bred into the ABH mouse background and EAE induced with spinal cord autoantigens the immune-enhancing effect of CB2 receptor deletion was lost. Likewise CB1 receptor and transient receptor potential vanilloid one knockout mice on the ABH background demonstrated no alteration in immune-susceptibility, in terms of disease incidence and severity of EAE, in contrast to that reported in some C57BL/6 mouse studies. Furthermore the immune-modulating influence of GPR55 was marginal on the ABH mouse background. Whilst sedative doses of tetrahydrocannabinol could induce immunosuppression, this was associated with a CB1 receptor rather than a CB2 receptor-mediated effect. These data support the fact that non-psychoactive doses of medicinal cannabis have a marginal influence on the immune response in MS. Importantly, it adds a note of caution for the translational

  1. Experimental and computational study of the effect of 1 atm background gas on nanoparticle generation in femtosecond laser ablation of metals

    Science.gov (United States)

    Wu, Han; Wu, Chengping; Zhang, Nan; Zhu, Xiaonong; Ma, Xiuquan; Zhigilei, Leonid V.

    2018-03-01

    Laser ablation of metal targets is actively used for generation of chemically clean nanoparticles for a broad range of practical applications. The processes involved in the nanoparticle formation at all relevant spatial and temporal scales are still not fully understood, making the precise control of the size and shape of the nanoparticles challenging. In this paper, a combination of molecular dynamics simulations and experiments is applied to investigate femtosecond laser ablation of aluminum targets in vacuum and in 1 atm argon background gas. The results of the simulations reveal a strong effect of the background gas environment on the initial plume expansion and evolution of the nanoparticle size distribution. The suppression of the generation of small/medium-size Al clusters and formation of a dense layer at the front of the expanding ablation plume, observed during the first nanosecond of the plume expansion in a simulation performed in the gas environment, have important implications on the characteristics of the nanoparticles deposited on a substrate and characterized in the experiments. The nanoparticles deposited in the gas environment are found to be more round-shaped and less flattened as compared to those deposited in vacuum. The nanoparticle size distributions exhibit power-law dependences with similar values of exponents obtained from fitting experimental and simulated data. Taken together, the results of this study suggest that the gas environment may be effectively used to control size and shape of nanoparticles generated by laser ablation.

  2. Pharmacokinetic/Pharmacodynamic Correlation of Cefquinome against Experimental Catheter-associated Biofilm Infection due to Staphylococcus aureus

    Directory of Open Access Journals (Sweden)

    Yu-Feng eZhou

    2016-01-01

    Full Text Available Biofilm formations play an important role in Staphylococcus aureus pathogenesis and contribute to antibiotic treatment failures in biofilm-associated infections. The aim of this study was to evaluate the pharmacokinetic/pharmacodynamic (PK/PD profiles of cefquinome against an experimental catheter-related biofilm model due to S. aureus, including three clinical isolates and one non-clinical isolate. The minimal inhibitory concentration (MIC, minimal biofilm inhibitory concentration (MBIC, biofilm bactericidal concentration (BBC, minimal biofilm eradication concentration (MBEC and biofilm prevention concentration (BPC and in vitro time-kill curves of cefquinome were studied in both planktonic and biofilm cells of study S. aureus strains. The in vivo post-antibiotic effects (PAEs, PK profiles and efficacy of cefquinome were performed in the catheter-related biofilm infection model in murine. A sigmoid Emax model was utilized to determine the PK/PD index that best described the dose-response profiles in the model.The MICs and MBICs of cefquinome for the four S. aureus strains were 0.5 and 16μg/mL, respectively. The BBCs (32-64 μg/mL and MBECs (64-256 μg/mL of these study strains were much higher than their corresponding BPC values (1-2 μg/mL. Cefquinome showed time-dependent killing both on planktonic and biofilm cells, but produced much shorter PAEs in biofilm infections. The best-correlated PK/PD parameters of cefquinome for planktonic and biofilm cells were the duration of time that the free drug level exceeded the MIC (fT>MIC, R2=96.2% and the MBIC (fT>MBIC, R2=94.7%, respectively. In addition, the AUC24h/MBIC of cefquinome also significantly correlated with the anti-biofilm outcome in this model (R2=93.1%. The values of AUC24h/MBIC for biofilm-static and 1-log10-unit biofilm-cidal activity were 22.8 h and 35.6 h; respectively. These results indicate that the PK/PD profiles of cefquinome could be used as valuable guidance for effective

  3. Estimation of efficacy of echinacea compositum C and teraflex application in orthodontic moving of teeth on the background of experimental goiter

    Directory of Open Access Journals (Sweden)

    Kolesnik K.A.

    2013-06-01

    Full Text Available Disturbances of the thyroid status may be negatively reflected on the biological processes underlying orthodontic tooth movement. Research object – in experiment to estimate efficacy of application of drug complex with osteotropic and immunomodulating action in orthodontic moving of teeth (ОМT on the background of euthyroid goiter. In 75 rats of Vistar line of gregarious breeding (females, 5 months, 210±28 g experimental goiter was modeled by injection of 1% perchlorate potassium solution with drinking water within 20 days. Intragastric solution of potassium Iodidum (PI in the dose of 20 mkg/kg was introduced to rats of the 3rd, 4th and 5th groups from the 22nd day. Intragastrically drug «Echinacea compositum C» was introduced to animals of the 3rd and 5th groups from the 22nd day during 5 days. OMT was reproduced on the 29th day from the beginning of experiment. On the background of PI injection, teraflex in a dose on glucosaminglican of 750 mg/kg was introduced to the rats of the 4th and 5th groups. A mandible for calculation of carious cavities and definition of atrophy degree of an alveolar process, and the maxilla – for definition of alkaline activity, acidic phosphatase, elastase and general proteolytic activity (GPA, pulp of incisors – for phosphatases definition of activity were isolated. Echinacea compositum, potassium Iodidum and teraflex in the idea of monotherapy caused some positive influence on phosphatases of an alveolar bone. To completely prevent disturbances of activity of bone phosphatases and proteinases was possibly only at application of a full complex: PІ – throughout all treatment, echinacea compositum C – before fixation of closing springs, teraflex – after fixation. Thus, stage-by-stage use of drugs – potassium Iodidum, «Echinacea compositum C» and Teraflex promoted to normalization of activity of alkaline and acidic phosphatase in pulp and bone tissue of alveolar process, and rendered protective

  4. Background Opacities

    NARCIS (Netherlands)

    Kamp, I.; Monier, R.; Smalley, B.; Wahlgren, G.; Stee, Ph.

    2010-01-01

    In NLTE computations of trace elements in stellar atmospheres, background opacities are generally treated in LTE. It is thus important to assess the impact of different methods of including this background opacity on the statistical equilibrium of the trace element and its resulting NLTE abundance.

  5. Multivariate phenotypic divergence due to the fixation of beneficial mutations in experimentally evolved lineages of a filamentous fungus

    NARCIS (Netherlands)

    Schoustra, S.E.; Punzalan, D.; Dali, R.; Rundle, H.D.; Kassen, R.

    2012-01-01

    The potential for evolutionary change is limited by the availability of genetic variation. Mutations are the ultimate source of new alleles, yet there have been few experimental investigations of the role of novel mutations in multivariate phenotypic evolution. Here, we evaluated the degree of

  6. Background Material

    DEFF Research Database (Denmark)

    Zandersen, Marianne; Hyytiäinen, Kari; Saraiva, Sofia

    This document serves as a background material to the BONUS Pilot Scenario Workshop, which aims to develop harmonised regional storylines of socio-ecological futures in the Baltic Sea region in a collaborative effort together with other BONUS projects and stakeholders.......This document serves as a background material to the BONUS Pilot Scenario Workshop, which aims to develop harmonised regional storylines of socio-ecological futures in the Baltic Sea region in a collaborative effort together with other BONUS projects and stakeholders....

  7. Quantifying flow retention due to vegetation in an earthen experimental channel using the Aggregated Dead Zone (ADZ) dilution approach

    NARCIS (Netherlands)

    Carling, Paul; Kleinhans, Maarten; Leyland, Julian; Besozzi, Louison; Duranton, Pierre; Trieu, Hai; Teske, Roy

    2014-01-01

    Understanding of flow resistance of forested floodplains is essential for floodplain flow routing and floodplain reforestation projects. Although the flow resistance of grass-lined channels is well-known, flow retention due to flow-blocking by trees is poorly understood. Flow behaviour through

  8. An Experimental Study of the Quantum Efficiency and Topology of Copper Photocathode Due to Plasma Cleaning and Etching

    CERN Document Server

    Palmer, Denni T; Kirby, Robert

    2005-01-01

    We have developed an experimental research program to the study of the photoemission properties of copper photocathodes as a function of various plasma cleaning/etching parameters. The quantum efficiency, QE, and topology, Ra and Rpp, of Copper Photocathodes, , will be monitored while undergoing plasma cleaning/etching process. We will monitor the QE as a function of time for the various test coupons while we optimize the various plasma processing parameters. In addition, surface topology, will be studied to determine the suitability of the cleaning/etching process to produce an acceptable photoemitter. We propose to use two metrics in the evaluation of the plasma cleaning process as an acceptable cleaning method for metallic photocathodes, Quantum Efficiency versus Wavelength and Surface roughness: Ra and Rpp represent the Average Roughness and Peak to Peak Roughness parameters, respectively.

  9. Effects of nutritional supplementation with l-arginine on repair of injuries due to muscle strain: experimental study on rats

    Directory of Open Access Journals (Sweden)

    Lauren Izabel Medeiros Couto

    2015-08-01

    Full Text Available ABSTRACTOBJECTIVE: To evaluate the influence of oral supplementation with arginine on regeneration of injuries due to straining of the anterior tibial muscle of rats. METHODS: Twenty-four Wistar rats of weight 492.5 ± 50.45 g were used. Injuries were induced through straining the anterior tibial muscles. The rats were separated into three groups of eight rats each. In the untreated group (UTG, after induction of injuries, the rats were observed for 24 h. In the simulation group (SG and the arginine group (AG respectively, the rats received isotonic saline solution and arginine solution via direct gavage, over a seven-day period. At the end of the period, blood samples were collected for serum evaluations of creatine kinase (CK, lactic dehydrogenase (LDH, aspartate aminotransferase (AST and C-reactive protein (CRP. The right and left anterior tibial muscles were resected for histopathological evaluations on the muscle injuries, investigating edema, hemorrhage and disorganization or morphometric alteration of the muscle fibers. The tissue repair was investigated in terms of proliferation of adipose tissue, angiogenesis and collagen fibers. The ANOVA and Student's tmethods were used and p≤ 0.05 was taken to be statistically significant. RESULTS: In the serum evaluations, the AG showed lower CK assay values and higher AST values. In the histopathological evaluation, the UTG presented edema and hemorrhage compatible with injuries due to strain; the SG presented edema and hemorrhage with proliferation of adipose tissue and collagen fibers; and the AG presented not only the findings of the SG but also, especially, intense angiogenesis. CONCLUSION: Oral supplementation with arginine did not cause any significant metabolic alterations that would contraindicate its use and it induced angiogenesis during the repair of muscles injured due to strain.

  10. Experimental study of heat transfer enhancement due to the surface vibrations in a flexible double pipe heat exchanger

    Science.gov (United States)

    Hosseinian, A.; Meghdadi Isfahani, A. H.

    2017-11-01

    In this study, the heat transfer enhancement due to the surface vibration for a double pipe heat exchanger, made of PVDF, is investigated. In order to create forced vibrations (3-9 m/s2, 100 Hz) on the outer surface of the heat exchanger electro-dynamic vibrators are used. Experiments were performed at inner Reynolds numbers ranging from 2533 to 9960. The effects of volume flow rate and temperature on heat transfer performance are evaluated. Results demonstrated that heat transfer coefficient increases by increasing vibration level and mass flow rate. The most increase in heat transfer coefficient is 97% which is obtained for the highest vibration level (9 m/s2) in the experiment range.

  11. In vivo magnetic resonance imaging investigating the development of experimental brain metastases due to triple negative breast cancer.

    Science.gov (United States)

    Hamilton, Amanda M; Foster, Paula J

    2017-02-01

    Triple negative breast cancer (TNBC), when associated with poor outcome, is aggressive in nature with a high incidence of brain metastasis and the shortest median overall patient survival after brain metastasis development compared to all other breast cancer subtypes. As therapies that control primary cancer and extracranial metastatic sites improve, the incidence of brain metastases is increasing and the management of patients with breast cancer brain metastases continues to be a significant clinical challenge. Mouse models have been developed to permit in depth evaluation of breast cancer metastasis to the brain. In this study, we compare the efficiency and metastatic potential of two experimental mouse models of TNBC. Longitudinal MRI analysis and end point histology were used to quantify initial cell arrest as well as the number and volume of metastases that developed in mouse brain over time. We showed significant differences in MRI appearance, tumor progression and model efficiency between the syngeneic 4T1-BR5 model and the xenogeneic 231-BR model. Since TNBC does not respond to many standard breast cancer treatments and TNBC brain metastases lack effective targeted therapies, these preclinical TNBC models represent invaluable tools for the assessment of novel systemic therapeutic approaches. Further pursuits of therapeutics designed to bypass the blood tumor barrier and permit access to the brain parenchyma and metastatic cells within the brain will be paramount in the fight to control and treat lethal metastatic cancer.

  12. Full-scale experimental and numerical study about structural behaviour of a thin-walled cold-formed steel building affected by ground settlements due to land subsidence

    Directory of Open Access Journals (Sweden)

    J. A. Ortiz

    2015-11-01

    Full Text Available Land subsidence due to ground water withdrawal is a problem in many places around the world (Poland, 1984. This causes differential ground settlements that affect masonry structures, because these structural materials do not exhibit an adequate performance beyond a certain level of angular distortion. This work presents the experimental and numerical results about a study regarding the performance of a full-scale thin-walled cold-formed steel building affected by ground differential settlements due to land subsidence. The experimental stage consisted in the construction of a test-building to be subjected to differential settlements in laboratory. The numerical stage consisted in performing a numerical non-linear static pull-down analysis simulating the differential ground settlements of the test-building. The results show that the structural performance of the tested building was very suitable in terms of ductility.

  13. Water quality simulation in two urban experimental catchments in Italy; Simulazione della qualita` delle acque in due bacini sperimentali urbani in Italia

    Energy Technology Data Exchange (ETDEWEB)

    Artina, S.; Maglionico, M. [Bologna Univ. (Italy). DISTART; Calabro`, P. [Reggio Calabria Univ. (Italy). Dip. di Meccanica dei Fluidi ed Ingegneria Off-shore; La Loggia, A. [Palermo Univ. (Italy). Dip. di Ingegneria Idraulica ed Applicazioni Ambientali

    1998-11-01

    Results of the calibration of SWMM on data coming from two Italian experimental catchments are presented, performed on runoff and quality data. The analysis has pointed on the great importance of runoff processes among all other phenomena taken into account. [Italiano] Viene presentata la calibrazione del modello SWMM dal punto quali-quantitativo su due bacini sperimentali italiani. Si e` compiuta la calibrazione e validazione del modello sugli eventi disponibili, valutandone il comportamento nel riprodurre gli eventi registrati. Lo studio mette in evidenza la particolare importanza del fenomeno del washoff operato dalla pioggia rispetto alle altre fasi della modellazione qualitativa.

  14. Efficacies of colistin and tigecycline in mice with experimental pneumonia due to NDM-1-producing strains of Klebsiella pneumoniae and Escherichia coli.

    Science.gov (United States)

    Docobo-Pérez, Fernando; Nordmann, Patrice; Domínguez-Herrera, Juan; López-Rojas, Rafael; Smani, Younes; Poirel, Laurent; Pachón, Jerónimo

    2012-03-01

    New Delhi metallo-β-lactamase-1 (NDM-1)-producing Enterobacteriaceae have emerged as a global threat. The aim of this study was to assess the efficacies of colistin and tigecycline in an experimental model of pneumonia caused by NDM-1-producing Escherichia coli and Klebsiella pneumoniae. The susceptibilities of K. pneumoniae NDM, E. coli NDM and K. pneumoniae ATCC 29665 were determined using the broth microdilution technique. The pharmacokinetics of colistin and tigecycline in an experimental model of pneumonia were performed using immunocompetent C57BL/6 mice. Mice were treated with colistin (60 mg/kg/day) or tigecycline (10 mg/kg/day). Mortality, bacteraemia and lung bacterial concentrations were recorded. The strains were susceptible to colistin and tigecycline. The ratio of area under the concentration-time curve/minimum inhibitory concentration (AUC/MIC) for colistin was 158.5 (all three strains) and that for tigecycline was 18.5 (K. pneumoniae NDM) and 37 (K. pneumoniae ATCC 29665 and E. coli NDM). In vivo, colistin decreased bacterial lung concentrations of K. pneumoniae NDM and K. pneumoniae ATCC 29665 by 1.16 log colony-forming units (CFU)/g and 2.23 logCFU/g, respectively, compared with controls (not significant). Tigecycline reduced K. pneumoniae NDM and K. pneumoniae ATCC 29665 load by 2.67 logCFU/g and 4.62 logCFU/g (Ppneumonia due to NDM-1-producing K. pneumoniae and its efficacy was suboptimal against NDM-1-producing E. coli. A high tigecycline dose was efficacious for treating experimental pneumonia due to NDM-1-producing E. coli and K. pneumoniae. Copyright © 2011 Elsevier B.V. and the International Society of Chemotherapy. All rights reserved.

  15. Do Dutch 11-12 years olds who never smoke, smoke experimentally or smoke regularly have different demographic backgrounds and perceptions of smoking?

    Science.gov (United States)

    Ausems, Marlein; Mesters, Ilse; van Breukelen, Gerard; De Vries, Hein

    2003-06-01

    Most adolescent smokers start smoking before the age of twelve. Little is known about the behavioural smoking determinants of Dutch primary school children. A cross-sectional study was carried out on a sample of students from the final year of 143 Dutch primary schools. A total of 3700 students (mean age = 11.6 years) completed a questionnaire based on the ASE model, measuring the attitude, social influences and self-efficacy expectations concerning smoking. Students were categorized as never smokers (64.3%), experimental smokers (28.0%), and regular smokers (7.8%). Multinomial logistic regression analyses showed that never smokers were younger, and were more often female, religious and from two-parent families than experimental smokers. Never smokers perceived more disadvantages, long-term physical consequences, more negative social norms and less pressure regarding smoking, higher self-efficacy expectations towards non-smoking, and had fewer parents, siblings or best friends who smoked. Looking at differences between experimental and regular smokers showed that experimental smokers received less pocket money. They also perceived more disadvantages, fewer advantages, more negative social norms and less pressure towards smoking, higher self-efficacy expectations towards non-smoking, and were less likely to be surrounded by friends, peers, family or teachers who smoked. Generally, the low scores for physical consequences and risk perception regarding addiction were striking. Smoking prevention aimed at primary schoolchildren should consider the different smoking categories, with their specific motives and influences. For instance, the influences on smoking initiation of parents, siblings and best friends suggest more comprehensive programmes aimed at the entire family. Youngsters' ignorance of addiction needs more attention.

  16. BACKGROUNDS OF EXPERIMENTAL INVESTIGATION OF ELECTROMAGNETIC COMPATIBILITY OF TRACTION ASYNCHRONOUS ELECTRIC DRIVES IN THE STRUCTURE OF DC TRACTION POWER SUPPLY SYSTEM

    Directory of Open Access Journals (Sweden)

    YU. S. Bondarenko

    2014-04-01

    Full Text Available Purpose. Application of physical modeling as a tool for research of any events or systems is becoming more widespread, including the field of railway transport. At the same time the adequacy of results that can be obtained, depends largely on the similarity degree of the physical model to real system. From the standpoint of the traction asynchronous electric drive (TAED research together with the traction power supply system research, the similarity can not be determined by the direct proportion of the parameters, because the processes nature accompanying the operation of these systems is non-linear. These features should be taken into account in the experimental setup, the basis for constructing of which is establishing of the system similarity that defines the purpose of this paper. Methodology. At the heart of the experimental setup creation laid reproduction of processes of energy transformation in the system of the DC traction power supply. Determination of the similarity degree of the proposed facility to the real system was carried out using the basic theorems of the similarity theory, their additional provisions on the complexity and nonlinear systems, as well as elements of mathematical analysis. Findings. According to the results of work: 1 The block diagram, the energy conversion mechanism of which is similar to the real system was received. This scheme is the basis of experimental setup, built in the future for the study of electromagnetic compatibility of TAED in the structure of DC traction electric power supply system. 2 Similarity of obtained structural scheme with the real system with the mechanism definition of calculating the scaling relations was established. Originality. In the process of establishing the similarity a simplified method for determining the scaling relations for nonlinear systems was suggested. They are identical in their structure components, but have different capacities. Practical value. Experimental

  17. The UO{sub 2} pellets plant experimental background of the established process; La Planta de Fabricacion de Pastillas de UO{sub 2} Bases Experimentales del proceso establecido

    Energy Technology Data Exchange (ETDEWEB)

    Aparicio Arroyo, E.; Alonso Folgueras, J. A.

    1969-07-01

    An account of the UO{sub 2} research and development carried out at the JEN is first given. This includes a 10 tons/year pellet Plant construction. Experimental background of the process is established, pointing out both milling advantages and risks, granulation devices, automatic press selection, binder removing and sintering furnaces. Origin, surface area, grain size and 0/U rate are considered as raw material reception parameters, although this process shows a wide scope. (Author) 13 refs.

  18. Experimental and Model Study of Changes in Spectral Solar Irradiance in the Atmosphere of Large City due to Tropospheric NO2 Content

    Science.gov (United States)

    Chubarova, N. Ye.; Larin, I. K.; Lebedev, V. V.; Partola, V. S.; Lezina, Ye. A.; Rublev, A. N.

    2009-03-01

    An experimental and model approach has been used to study the NO2 vertical profiles and its effect on solar irradiance. The profiles of NO2 were obtained using gas analyzers, which had been installed at different levels at the Moscow State University (MSU) located at the south-western part of Moscow and at the Ostankino tower located at the north of Moscow up to the height of 350 m. Using these data diurnal and spatial variability of the NO2 content in the most polluted part of planetary boundary layer (PBL) has been analyzed within the large megalopolis. On the base of photochemical modeling we have simulated the diurnal cycle of NO2 vertical profiles for summer and winter conditions and have compared the results with the experimental ones. Using the RT modeling with input gaseous and aerosol parameters of the atmosphere obtained from the MSU Meteorological Observatory we have estimated the attenuation of spectral solar irradiance in UV and visible region of spectrum due to the NO2 content in the polluted atmosphere for different seasons.

  19. Minimizing the background radiation in the new neutron time-of-flight facility at CERN FLUKA Monte Carlo simulations for the optimization of the n_TOF second experimental line

    CERN Document Server

    Bergström, Ida; Elfgren, Erik

    2013-06-11

    At the particle physics laboratory CERN in Geneva, Switzerland, the Neutron Time-of-Flight facility has recently started the construction of a second experimental line. The new neutron beam line will unavoidably induce radiation in both the experimental area and in nearby accessible areas. Computer simulations for the minimization of the background were carried out using the FLUKA Monte Carlo simulation package. The background radiation in the new experimental area needs to be kept to a minimum during measurements. This was studied with focus on the contributions from backscattering in the beam dump. The beam dump was originally designed for shielding the outside area using a block of iron covered in concrete. However, the backscattering was never studied in detail. In this thesis, the fluences (i.e. the flux integrated over time) of neutrons and photons were studied in the experimental area while the beam dump design was modified. An optimized design was obtained by stopping the fast neutrons in a high Z mat...

  20. Numerical and experimental investigation of light emissions of a planar nitrogen atmospheric-pressure dielectric barrier discharge due to addition of ammonia considering oxygen impurity

    Science.gov (United States)

    Li, F.-L.; Hung, C.-T.; Lin, K.-M.; Wei, T.-C.; Wu, J.-S.

    2013-12-01

    In this paper, the mechanisms of light emissions, including NO-γ, NO-β and N2-SPS, produced in a N2/NH3 atmospheric-pressure dielectric barrier discharge considering realistic oxygen impurity (30 ppm) are investigated numerically and experimentally. Self-consistent, one-dimensional fluid modeling is used to numerically simulate the discharge process with 48 species and 235 reaction channels. An optical emission spectrometer (OES) is used to measure the relative intensities of the light emission. The simulations of the light emission intensities for the above-mentioned OES lines generally reproduce the trends observed in the experiments caused by changes in the NH3 concentration. All of the predicted intensities of NO-γ, NO-β and N2-SPS decrease with increasing amount of NH3 caused by various reaction mechanisms. The former is due to the loss of N2(A) and NO(A) by the reaction of NH3 with N2(A) and NO(A), respectively. The decrease in NO-β is due to the depletion of N and O because of NH3, and the decrease in N2-SPS is due to electron attachment to NH3 and a weaker metastable-metastable associative ionization of N2. All of the simulated results demonstrate that the discharges are typically Townsend-like because the ions outnumber the electrons and the electric field across the gap is distorted only slightly by the charged particles during the breakdown. Finally, a reduced chemical kinetics model for a planar atmospheric-pressure N2/O2/NH3 dielectric barrier discharge is proposed and validated by benchmarking against the above complete chemical kinetics. This results in a reduced chemical kinetics consisting of 33 species and 87 reactions with a very limited loss of accuracy of discharge properties, while it is 2.1 times faster in computational time as compared with the complete version.

  1. EFFECTS OF NATURAL ORIFICE SECRETIONS IN PERITONEAL CAVITY IN THE BACKGROUND OF NATURAL ORIFICE TRANSLUMINAL ENDOSCOPIC SURGERY (NOTES AN EXPERIMENTAL STUDY IN ANIMALS

    Directory of Open Access Journals (Sweden)

    Devendra

    2015-03-01

    Full Text Available Natural Orifice Transluminal Endoscopic Surgery (NOTES is a new form of minimally invasive surgery which eliminates traditional skin incisions by accessing internal body cavities through natural orifices. In our experimental animal study, we compared the incidences intraperitoneal abscess formation , culture swab of peritoneal cavity positive for organism, intraperitoneal adhesion formation and mean adhesion score before and after lavaging the portal of entry of albino rat , i.e. transgastric and transvaginal. On vaginal route as a portal of entry into peritoneal cavity , on the 7th day , 66% rats developed abscesses , 88% rats had culture swab positive and 88% rats developed intraperitoneal adhesion (grade - 2 before any cleansing of vaginal cavity with antiseptic solution . Now after lavage with povidone iodine solution, only 11% developed abscesses , 22% were peritoneal swab culture positive and 33% had interbowel and parietal adhesion of (grade 0 - 1. On 21 st day , the complication observed was adhesion formation in pre lavage group of 66% incidence and 16% after vaginal lavage. The incidence of complications were reduced significantly after lavage with antiseptic solution as shown by p values (p<0.01 for abscess formation, p< 0.01 for culture positivity and p< 0.01 for adhesions formation. Also the mean adhesion scoring was significantly reduced (p <0.02 after vaginal lavage on the 7 th day. Gastric route as the portal of entry into the peritoneal cavity, again the same variables were compared on the 7th and the 21st day , but wash was given with antibiotic solution (Cefazolin. On the 7th day , 44% had abscesses, 77% were culture positive and 66% had adhesions (Grade 1 - 2 before gastric lavage with antibiotic solution . After wash of stomach, 11% were culture positive and 44% developed adhesions (Grade 0 - 1. Here, abscess formation (p<0.02 and mean adhesion scoring (p<0.05 were significantly reduced after stomach wash. On the 21st day

  2. An experimental investigation of the hemodynamic variations due to aplastic vessels within three-dimensional phantom models of the Circle of Willis.

    LENUS (Irish Health Repository)

    Fahy, Paul

    2013-09-10

    A complete circle of Willis (CoW) is found in approximately 30-50% of the population. Anatomical variations, such as absent or surgically clamped vessels, can result in undesirable flow patterns. These can affect the brain\\'s ability to maintain cerebral perfusion and the formation of cerebral aneurysms. An experimental test system was developed to simulate cerebral physiological conditions through three flexible 3D patient-specific models of complete and incomplete CoW geometries. Flow visualizations were performed with isobaric dyes and the mapped dye streamlines were tracked throughout the models. Three to seven flow impact locations were observed for all configurations, corresponding to known sites for aneurysmal formation. Uni and bi-directional cross-flows occurred along the communicating arteries. The greatest shunting of flow occurred for a missing pre-communicating anterior (A1) and posterior (P1) cerebral arteries. The anterior cerebral arteries had the greatest reduction (15-37%) in efferent flow rates for missing either a unilateral A1 or bilateral P1 segments. The bi-directional cross-flows, with multiple afferent flow mixing, observed along the communicating arteries may explain the propensity of aneurysm formation at these sites. Reductions in efferent flow rates due to aplastic vessel configurations may affect normal brain function.

  3. Therapeutic Effect of Human Adipose Tissue-Derived Mesenchymal Stem Cells in Experimental Corneal Failure Due to Limbal Stem Cell Niche Damage.

    Science.gov (United States)

    Galindo, Sara; Herreras, José M; López-Paniagua, Marina; Rey, Esther; de la Mata, Ana; Plata-Cordero, María; Calonge, Margarita; Nieto-Miguel, Teresa

    2017-10-01

    Limbal stem cells are responsible for the continuous renewal of the corneal epithelium. The destruction or dysfunction of these stem cells or their niche induces limbal stem cell deficiency (LSCD) leading to visual loss, chronic pain, and inflammation of the ocular surface. To restore the ocular surface in cases of bilateral LSCD, an extraocular source of stem cells is needed to avoid dependence on allogeneic limbal stem cells that are difficult to obtain, isolate, and culture. The aim of this work was to test the tolerance and the efficacy of human adipose tissue-derived mesenchymal stem cells (hAT-MSCs) to regenerate the ocular surface in two experimental models of LSCD that closely resemble different severity grades of the human pathology. hAT-MSCs transplanted to the ocular surface of the partial and total LSCD models developed in rabbits were well tolerated, migrated to inflamed tissues, reduced inflammation, and restrained the evolution of corneal neovascularization and corneal opacity. The expression profile of the corneal epithelial cell markers CK3 and E-cadherin, and the limbal epithelial cell markers CK15 and p63 was lost in the LSCD models, but was partially recovered after hAT-MSC transplantation. For the first time, we demonstrated that hAT-MSCs improve corneal and limbal epithelial phenotypes in animal LSCD models. These results support the potential use of hAT-MSCs as a novel treatment of ocular surface failure due to LSCD. hAT-MSCs represent an available, non-immunogenic source of stem cells that may provide therapeutic benefits in addition to reduce health care expenses. Stem Cells 2017;35:2160-2174. © 2017 AlphaMed Press.

  4. Addition of gentamicin or rifampin does not enhance the effectiveness of daptomycin in treatment of experimental endocarditis due to methicillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    Miró, J M; García-de-la-Mària, C; Armero, Y; Soy, D; Moreno, A; del Río, A; Almela, M; Sarasa, M; Mestres, C A; Gatell, J M; Jiménez de Anta, M T; Marco, F

    2009-10-01

    This study evaluated the activity of daptomycin combined with either gentamicin or rifampin against three methicillin-resistant Staphylococcus aureus (MRSA) clinical isolates in vitro and one isolate in vivo against a representative strain (MRSA-572). Time-kill experiments showed that daptomycin was bactericidal against these strains at concentrations over the MIC. Daptomycin at sub-MIC concentrations plus gentamicin at 1x and 2x the MIC yielded synergy, while the addition of rifampin at 2 to 4 microg/ml resulted in indifference (two strains) or antagonism (one strain). The in vivo activity of daptomycin (6 mg/kg of body weight once a day) was evaluated +/- gentamicin (1 mg/kg intravenously [i.v.] every 8 h [q8h]) or rifampin (300 mg i.v. q8h) in a rabbit model of infective endocarditis by simulating human pharmacokinetics. Daptomycin plus gentamicin (median, 0 [interquartile range, 0 to 2] log10 CFU/g vegetation) was as effective as daptomycin alone (0 [0 to 2] log10 CFU/g vegetation) in reducing the density of bacteria in valve vegetations (P = 0.83), and both were more effective than daptomycin plus rifampin (3 [2 to 3.5] log10 CFU/g vegetation; P gentamicin (10/15 [67%] versus 9/15 [60%]; P = 0.7), and both regimens did so more than daptomycin plus rifampin (3/15 [20%]; P = 0.01 and P = 0.02, respectively). No statistical difference was noted between daptomycin plus gentamicin and daptomycin alone for MRSA treatment. In the combination arm, all isolates from vegetations remained susceptible to daptomycin, gentamicin, and rifampin. Sixty-one percent of the isolates (8/13) acquired resistance to rifampin during monotherapy. In the daptomycin arm, resistance was detected in only one case, in which the daptomycin MIC rose to 2 microg/ml among the recovered bacteria. In conclusion, the addition of gentamicin or rifampin does not enhance the effectiveness of daptomycin in the treatment of experimental endocarditis due to MRSA.

  5. Estimate of the $m_H$ shift due to interference between signal and background processes in the $H \\rightarrow \\gamma\\gamma$ channel, for the $\\sqrt{s} = 8$ TeV dataset recorded by ATLAS

    CERN Document Server

    The ATLAS collaboration

    2016-01-01

    In the context of precision measurements of the properties of the Higgs boson, one of the most fundamental parameters is the knowledge of its mass. One of the achievements of the first run of the LHC is the precise estimate of the Higgs Boson mass, that has been measured by the ATLAS and CMS collaborations at a precision of 0.2\\% using $H \\to \\gamma \\, \\gamma$ and $H \\to Z \\, Z^* \\to 4 \\ell$ final states. In the analysis of the experimental data, interference effects of non-resonant $gg \\to \\gamma \\gamma$ and other processes with resonant $gg \\to H \\to \\gamma \\gamma$ production are not taken into account. The real part of the interference terms change the line-shape of $m_{\\gamma \\gamma}$ in such a way that an apparent mass shift appears. In this note a study is carried out that quantifies the expected shift of the mass peak position for the SM Higgs boson in the $H \\to \\gamma \\gamma$ channel for the ATLAS measurement. The purpose is to perform this analysis using the correct detector description and event ca...

  6. Standard Model backgrounds to supersymmetry searches

    CERN Document Server

    Mangano, Michelangelo L

    2009-01-01

    This work presents a review of the Standard Model sources of backgrounds to the search of supersymmetry signals. Depending on the specific model, typical signals may include jets, leptons, and missing transverse energy due to the escaping lightest supersymmetric particle. We focus on the simplest case of multijets and missing energy, since this allows us to expose most of the issues common to other more complex cases. The review is not exhaustive, and is aimed at collecting a series of general comments and observations, to serve as guideline for the process that will lead to a complete experimental determination of size and features of such SM processes.

  7. Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa

    DEFF Research Database (Denmark)

    van Gennip, M; Moser, Claus; Christensen, Louise D

    2009-01-01

    Background: Effects of treatment with tobramycin initiated 1 or 24 h post-infection were investigated in a new version of a pulmonary infection model in mice. The model reflects the differentiated behaviour of Pseudomonas aeruginosa mucoid strains isolated from the lungs of one chronically infect...

  8. Net Loss of CaCO3 from a subtropical calcifying community due to seawater acidification: Mesocosm-scale experimental evidence

    Science.gov (United States)

    Andersson, A.J.; Kuffner, I.B.; MacKenzie, F.T.; Jokiel, P.L.; Rodgers, K.S.; Tan, A.

    2009-01-01

    Acidification of seawater owing to oceanic uptake of atmospheric CO 2 originating from human activities such as burning of fossil fuels and land-use changes has raised serious concerns regarding its adverse effects on corals and calcifying communities. Here we demonstrate a net loss of calcium carbonate (CaCO3) material as a result of decreased calcification and increased carbonate dissolution from replicated subtropical coral reef communities (N=3) incubated in continuous-flow mesocosms subject to future seawater conditions. The calcifying community was dominated by the coral Montipora capitata. Daily average community calcification or Net Ecosystem Calcification (NECC=CaCO3 production - dissolution) was positive at 3.3 mmol CaCO3 m-2 h-1 under ambient seawater pCO2 conditions as opposed to negative at -0.04 mmol CaCO3 m-2 h-1 under seawater conditions of double the ambient pCO2. These experimental results provide support for the conclusion that some net calcifying communities could become subject to net dissolution in response to anthropogenic ocean acidification within this century. Nevertheless, individual corals remained healthy, actively calcified (albeit slower than at present rates), and deposited significant amounts of CaCO3 under the prevailing experimental seawater conditions of elevated pCO2.

  9. Net Loss of CaCO3 from a subtropical calcifying community due to seawater acidification: mesocosm-scale experimental evidence

    Directory of Open Access Journals (Sweden)

    K. S. Rodgers

    2009-08-01

    Full Text Available Acidification of seawater owing to oceanic uptake of atmospheric CO2 originating from human activities such as burning of fossil fuels and land-use changes has raised serious concerns regarding its adverse effects on corals and calcifying communities. Here we demonstrate a net loss of calcium carbonate (CaCO3 material as a result of decreased calcification and increased carbonate dissolution from replicated subtropical coral reef communities (n=3 incubated in continuous-flow mesocosms subject to future seawater conditions. The calcifying community was dominated by the coral Montipora capitata. Daily average community calcification or Net Ecosystem Calcification (NEC=CaCO3 production – dissolution was positive at 3.3 mmol CaCO3 m−2 h−1 under ambient seawater pCO2 conditions as opposed to negative at −0.04 mmol CaCO3 m−2 h−1 under seawater conditions of double the ambient pCO2. These experimental results provide support for the conclusion that some net calcifying communities could become subject to net dissolution in response to anthropogenic ocean acidification within this century. Nevertheless, individual corals remained healthy, actively calcified (albeit slower than at present rates, and deposited significant amounts of CaCO3 under the prevailing experimental seawater conditions of elevated pCO2.

  10. Inhibition of Na(+),K(+)-ATPase in the hypothalamus, pons and cerebellum of the offspring rat due to experimentally-induced maternal hypothyroidism.

    Science.gov (United States)

    Koromilas, Christos; Liapi, Charis; Zarros, Apostolos; Tsela, Smaragda; Zissis, Konstantinos M; Kalafatakis, Konstantinos; Skandali, Nikolina; Voumvourakis, Konstantinos; Carageorgiou, Haris; Tsakiris, Stylianos

    2015-08-01

    Neurodevelopment is known to be particularly susceptible to thyroid hormone insufficiency and can result in extensive structural and functional deficits within the central nervous system (CNS), subsequently leading to the establishment of cognitive impairment and neuropsychiatric symptomatology. The current study evaluated the effects of gestational and/or lactational maternal exposure to propylthiouracil (PTU)-induced hypothyroidism (as a suggestive multilevel experimental approach to the study of hypothyroidism-induced changes that has been developed and characterized by the authors) on crucial brain enzyme activities of 21-day-old Wistar rat offspring in a CNS region-specific manner. The activities of acetylcholinesterase (AChE), Na(+),K(+)-ATPase and Mg(2+)-ATPase in the offspring hypothalamus, cerebellum and pons were assessed. The study demonstrated that maternal exposure to PTU (0.05% w/v in the drinking water) during the critical periods of neurodevelopment can result in an inhibition of hypothalamic, pontine and cerebellar Na(+),K(+)-ATPase; a major marker of neuronal excitability and metabolic energy production as well as an important regulator of important systems of neurotransmission. On the other hand, no significant changes in the activities of the herein offspring CNS regions' AChE and Mg(2+)-ATPase were recorded. The observed Na(+),K(+)-ATPase inhibition: (i) is region-specific (and non-detectable in whole brain homogenetes), (ii) could constitute a central event in the pathophysiology of clinically-relevant hypothyroidism-associated developmental neurotoxicity, (iii) occurs under all examined experimental schemes, and (iv) certainly deserves further clarification at a molecular and histopathological level. As these findings are analyzed and compared to the available literature, they also underline the need for the adoption and further study of Na(+),K(+)-ATPase activity as a consistent neurochemical marker within the context of a systematic

  11. Neck/shoulder discomfort due to visually demanding experimental near work is influenced by previous neck pain, task duration, astigmatism, internal eye discomfort and accommodation.

    Science.gov (United States)

    Zetterberg, Camilla; Forsman, Mikael; Richter, Hans O

    2017-01-01

    Visually demanding near work can cause eye discomfort, and eye and neck/shoulder discomfort during, e.g., computer work are associated. To investigate direct effects of experimental near work on eye and neck/shoulder discomfort, 33 individuals with chronic neck pain and 33 healthy control subjects performed a visual task four times using four different trial lenses (referred to as four different viewing conditions), and they rated eye and neck/shoulder discomfort at baseline and after each task. Since symptoms of eye discomfort may differ depending on the underlying cause, two categories were used; internal eye discomfort, such as ache and strain, that may be caused by accommodative or vergence stress; and external eye discomfort, such as burning and smarting, that may be caused by dry-eye disorders. The cumulative performance time (reflected in the temporal order of the tasks), astigmatism, accommodation response and concurrent symptoms of internal eye discomfort all aggravated neck/shoulder discomfort, but there was no significant effect of external eye discomfort. There was also an interaction effect between the temporal order and internal eye discomfort: participants with a greater mean increase in internal eye discomfort also developed more neck/shoulder discomfort with time. Since moderate musculoskeletal symptoms are a risk factor for more severe symptoms, it is important to ensure a good visual environment in occupations involving visually demanding near work.

  12. Neck/shoulder discomfort due to visually demanding experimental near work is influenced by previous neck pain, task duration, astigmatism, internal eye discomfort and accommodation.

    Directory of Open Access Journals (Sweden)

    Camilla Zetterberg

    Full Text Available Visually demanding near work can cause eye discomfort, and eye and neck/shoulder discomfort during, e.g., computer work are associated. To investigate direct effects of experimental near work on eye and neck/shoulder discomfort, 33 individuals with chronic neck pain and 33 healthy control subjects performed a visual task four times using four different trial lenses (referred to as four different viewing conditions, and they rated eye and neck/shoulder discomfort at baseline and after each task. Since symptoms of eye discomfort may differ depending on the underlying cause, two categories were used; internal eye discomfort, such as ache and strain, that may be caused by accommodative or vergence stress; and external eye discomfort, such as burning and smarting, that may be caused by dry-eye disorders. The cumulative performance time (reflected in the temporal order of the tasks, astigmatism, accommodation response and concurrent symptoms of internal eye discomfort all aggravated neck/shoulder discomfort, but there was no significant effect of external eye discomfort. There was also an interaction effect between the temporal order and internal eye discomfort: participants with a greater mean increase in internal eye discomfort also developed more neck/shoulder discomfort with time. Since moderate musculoskeletal symptoms are a risk factor for more severe symptoms, it is important to ensure a good visual environment in occupations involving visually demanding near work.

  13. Inflammation and oxidative stress in corneal tissue in experimental keratitis due to Fusarium solani: Amelioration following topical therapy with voriconazole and epigallocatechin gallate.

    Science.gov (United States)

    Ruban, Vasanthakumar V; Archana, Philip T; Sundararajan, Mahalingam; Geraldine, Pitchairaj; Thomas, Philip A

    2017-10-24

    Combined antifungal and antioxidant therapy may help to reduce oxidative stress in fungal keratitis. Experimental Fusarium solani keratitis was induced by application of F. solani conidia to scarified cornea (right eye) of 16 rabbits (another four rabbits were negative controls [Group I]). Five days later, F. solani-infected animals began receiving hourly topical saline alone (Group II), voriconazole (10 mg/mL) alone (Group III), epigallocatechin gallate (EGCG, 10 mg/mL) alone (Group IV) or voriconazole and EGCG (Group V). Twenty days post-inoculation, corneal lesions were graded. After animal sacrifice, excised corneas underwent histopathological and microbiological investigations. Corneal tissue levels/activities of interleukin 1 beta (IL-1β) and tumour necrosis factor alpha (TNF-α) gene mRNA transcripts, matrix metalloproteinase (MMP) 2 and 9 proteins, malondialdehyde (MDA) and reduced glutathione (GSH), and superoxide dismutase (SOD), catalase (CAT) and glutathione peroxidase (GPx), were also measured. Clinical and histopathological scores (severity of corneal lesions; [P  Groups IV and III > Groups V and I. Mean SOD, CAT, GPx and GSH levels (P solani keratitis, as manifested by improved clinical, histological, microbiological and molecular parameters. © 2017 Blackwell Verlag GmbH.

  14. Experimental facts supporting a red marrow uptake due to radiometal transchelation in {sup 90}Y-DOTATOC therapy and relationship to the decrease of platelet counts

    Energy Technology Data Exchange (ETDEWEB)

    Walrand, Stephan; Barone, Raffaella; Pauwels, Stanislas; Jamar, Francois [Universite Catholique de Louvain, Centre de Medecine Nucleaire, Brussels (Belgium)

    2011-07-15

    The aim of this study was to retrospectively evaluate whether the red marrow (RM) takes up {sup 111}In-diethylenetriaminepentaacetic acid (DTPA)-D-Phe{sup 1}-octreotide and {sup 86}Y-DOTATOC and to assess the correlation between the RM absorbed doses and platelet count reduction as a biological dose estimate. Data from 12 patients who underwent at 24 h p.i. high statistics {sup 111}In single photon emission computed tomography (SPECT) and {sup 86}Y positron emission tomography (PET) acquisitions of the chest were analysed. Uptake was measured on >7 cm spine length and converted to total RM uptake using standard RM distribution in man. RM absorbed doses were calculated assuming specific RM uptake and using the plasma and remainder of the body models. RM doses were correlated with the platelet count reduction at 4 weeks. In vitro experiments explored the metabolism of {sup 111}In-DTPA-D-Phe{sup 1}-octreotide and {sup 90}Y-DOTATOC in plasma. The correlation between the uptake of both tracers was excellent (R = 0.80), indicating that RM uptake of {sup 86}Y-DOTATOC reflects a real physiological process and not reconstruction artefacts. The kinetics of {sup 86}Y-DOTATOC RM activity was different than that in blood and tumours, with no activity at 4 h p.i. indicating that the uptake is not somatostatin receptor dependent. In vitro experiments showed a transchelation of both radiometals to free transferrin that could explain the RM uptake. In patients without chemotherapy and with a normal platelet count recovery, a good correlation (R = 0.96) was found between the RM doses and the platelet count reduction at the nadir. These experimental facts support the existence of a true RM uptake likely related to transchelation of the radiometal to transferrin. RM uptake correlates well with the observed acute RM toxicity. (orig.)

  15. Building Background Knowledge

    Science.gov (United States)

    Neuman, Susan B.; Kaefer, Tanya; Pinkham, Ashley

    2014-01-01

    This article make a case for the importance of background knowledge in children's comprehension. It suggests that differences in background knowledge may account for differences in understanding text for low- and middle-income children. It then describes strategies for building background knowledge in the age of common core standards.

  16. Setting up of a theoretical-experimental approach for the measurement of the vibrational impact on cultural heritages due to vehicular traffic

    Directory of Open Access Journals (Sweden)

    Salvatore Barbaro

    2006-02-01

    Full Text Available During the last years, the constant increase of the request for transport by road and by rail, connected to the economic and social development process, has provoked the birth of the phenomenon of the vibrations induced by the means of transports, with the result of stimulating the resident population's curiosity and the technical personnel's interest. Into the historic centres of the towns, it is possible to trace a series of concomitant factors that tend further to increase this process: the road superstructure mostly used in the historical centres are often stony, and their usage is due mainly to aesthetic reasons; the no-measurement or the lack of maintenance are often the causes of high levels of roughness; the buildings set into the historical centres have got a historical-art value of primary importance and some part of them (such as mosaics, pictures, etc. are very sensitive to vibrations, being sticking to the outside walls; According to what said above, the noisy and vibrations provoked by the road traffic are becoming even more one of the main cause of the environmental damage.

  17. Pre- and post-experimental manipulation assessments confirm the increase in number of birds due to the addition of nest boxes

    Directory of Open Access Journals (Sweden)

    Cecilia Cuatianquiz Lima

    2016-03-01

    Full Text Available Secondary cavity nesting (SCN birds breed in holes that they do not excavate themselves. This is possible where there are large trees whose size and age permit the digging of holes by primary excavators and only rarely happens in forest plantations, where we expected a deficit of both breeding holes and SCN species. We assessed whether the availability of tree cavities influenced the number of SCNs in two temperate forest types, and evaluated the change in number of SCNs after adding nest boxes. First, we counted all cavities within each of our 25-m radius sampling points in mature and young forest plots during 2009. We then added nest boxes at standardised locations during 2010 and 2011 and conducted fortnightly bird counts (January–October 2009–2011. In 2011 we added two extra plots of each forest type, where we also conducted bird counts. Prior to adding nest boxes, counts revealed more SCNs in mature than in young forest. Following the addition of nest boxes, the number of SCNs increased significantly in the points with nest boxes in both types of forest. Counts in 2011 confirmed the increase in number of birds due to the addition of nest boxes. Given the likely benefits associated with a richer bird community we propose that, as is routinely done in some countries, forest management programs preserve old tree stumps and add nest boxes to forest plantations in order to increase bird numbers and bird community diversity.

  18. A due

    DEFF Research Database (Denmark)

    to acknowledge the excellence of these two scholars by a double Festschrift, "A due". Both have been working at the Music Department of the University of Copenhagen and have collaborated with The Royal Library on various projects. This publication contains contributions from 44 colleagues, who thus - in topics...

  19. Gamma-ray Background Spectrum and Annihilation Rate in the Baryon-symmetric Big-bang Cosmology

    Science.gov (United States)

    Puget, J. L.

    1973-01-01

    An attempt was made to acquire experimental information on the problem of baryon symmetry on a large cosmological scale by observing the annihilation products. Data cover absorption cross sections and background radiation due to other sources for the two main products of annihilation, gamma rays and neutrinos. Test results show that the best direct experimental test for the presence of large scale antimatter lies in the gamma ray background spectrum between 1 and 70 MeV.

  20. EPR Line Shifts and Line Shape Changes Due to Heisenberg Spin Exchange and Dipole-Dipole Interactions of Nitroxide Free Radicals in Liquids: 8. Further Experimental and Theoretical Efforts to Separate the Effects of the Two Interactions

    Science.gov (United States)

    Peric, Mirna; Bales, Barney L; Peric, Miroslav

    2012-01-01

    The work in Part 6 of this series (J. Phys. Chem. A 2009, 113, 4930), addressing the task of separating the effects of Heisenberg spin exchange (HSE) and dipole-dipole (DD) interactions on EPR spectra of nitroxide spin probes in solution, is extended experimentally and theoretically. Comprehensive measurements of perdeuterated 2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl (pDT) in squalane, a viscous alkane, paying special attention to lower temperatures and lower concentrations were carried out in an attempt to focus on DD, the lesser understood of the two interactions. Theoretically, the analysis has been extended to include the recent comprehensive treatment by Salikhov (Appl. Magn. Reson. 2010, 38, 237). In dilute solutions, both interactions (1) introduce a dispersion component, (2) broaden the lines, and (3) shift the lines. DD introduces a dispersion component proportional to the concentration and of opposite sign to that of HSE. Equations relating the EPR spectral parameters to the rate constants due HSE and DD have been derived. By employing non-linear least-squares fitting of theoretical spectra to a simple analytical function and the proposed equations, the contributions of the two interactions to items (1)–(3) may be quantified and compared with the same parameters obtained by fitting experimental spectra. This comparison supports the theory in its broad predictions, however, at low temperatures, the DD contribution to the experimental dispersion amplitude does not increase linearly with concentration. We are unable to deduce if this discrepancy is due to inadequate analysis of the experimental data or an incomplete theory. A key new aspect of the more comprehensive theory is that there is enough information in the experimental spectra to find items (1)–(3) due to both interactions; however, in principle, appeal must be made to a model of molecular diffusion to separate the two. The permanent diffusion model is used to illustrate the separation in this

  1. Electron paramagnetic resonance line shifts and line shape changes due to heisenberg spin exchange and dipole-dipole interactions of nitroxide free radicals in liquids 8. Further experimental and theoretical efforts to separate the effects of the two interactions.

    Science.gov (United States)

    Peric, Mirna; Bales, Barney L; Peric, Miroslav

    2012-03-22

    The work in part 6 of this series (J. Phys. Chem. A 2009, 113, 4930), addressing the task of separating the effects of Heisenberg spin exchange (HSE) and dipole-dipole interactions (DD) on electron paramagnetic resonance (EPR) spectra of nitroxide spin probes in solution, is extended experimentally and theoretically. Comprehensive measurements of perdeuterated 2,2,6,6-tetramethyl-4-oxopiperidine-1-oxyl (pDT) in squalane, a viscous alkane, paying special attention to lower temperatures and lower concentrations, were carried out in an attempt to focus on DD, the lesser understood of the two interactions. Theoretically, the analysis has been extended to include the recent comprehensive treatment by Salikhov (Appl. Magn. Reson. 2010, 38, 237). In dilute solutions, both interactions (1) introduce a dispersion component, (2) broaden the lines, and (3) shift the lines. DD introduces a dispersion component proportional to the concentration and of opposite sign to that of HSE. Equations relating the EPR spectral parameters to the rate constants due to HSE and DD have been derived. By employing nonlinear least-squares fitting of theoretical spectra to a simple analytical function and the proposed equations, the contributions of the two interactions to items 1-3 may be quantified and compared with the same parameters obtained by fitting experimental spectra. This comparison supports the theory in its broad predictions; however, at low temperatures, the DD contribution to the experimental dispersion amplitude does not increase linearly with concentration. We are unable to deduce whether this discrepancy is due to inadequate analysis of the experimental data or an incomplete theory. A new key aspect of the more comprehensive theory is that there is enough information in the experimental spectra to find items 1-3 due to both interactions; however, in principle, appeal must be made to a model of molecular diffusion to separate the two. The permanent diffusion model is used to

  2. Cosmogenic Backgrounds to 0{\

    CERN Document Server

    :,; Auty, D J; Barbeau, P S; Beck, D; Belov, V; Breidenbach, M; Brunner, T; Burenkov, A; Cao, G F; Chambers, C; Cleveland, B; Coon, M; Craycraft, A; Daniels, T; Danilov, M; Daugherty, S J; Davis, J; Delaquis, S; Der Mesrobian-Kabakian, A; DeVoe, R; Didberidze, T; Dilling, J; Dolgolenko, A; Dolinski, M J; Dunford, M; Fairbank, W; Farine, J; Feldmeier, W; Feyzbakhsh, S; Fierlinger, P; Fudenberg, D; Gornea, R; Graham, K; Gratta, G; Hall, C; Herrin, S; Hughes, M; Jewell, M J; Johnson, A; Johnson, T N; Johnston, S; Karelin, A; Kaufman, L J; Killick, R; Koffas, T; Kravitz, S; Krücken, R; Kuchenkov, A; Kumar, K S; Leonard, D S; Licciardi, C; Lin, Y H; Ling, J; MacLellan, R; Marino, M G; Mong, B; Moore, D; Njoya, O; Nelson, R; Odian, A; Ostrovskiy, I; Piepke, A; Pocar, A; Prescott, C Y; Retière, F; Rowson, P C; Russell, J J; Schubert, A; Sinclair, D; Smith, E; Stekhanov, V; Tarka, M; Tolba, T; Tsang, R; Twelker, K; Vuilleumier, J -L; Waite, A; Walton, J; Walton, T; Weber, M; Wen, L J; Wichoski, U; Wood, J; Yang, L; Yen, Y -R; Zeldovich, O Ya

    2015-01-01

    As neutrinoless double-beta decay experiments become more sensitive and intrinsic radioactivity in detector materials is reduced, previously minor contributions to the background must be understood and eliminated. With this in mind, cosmogenic backgrounds have been studied with the EXO-200 experiment. Using the EXO-200 TPC, the muon flux (through a flat horizontal surface) underground at the Waste Isolation Pilot Plant (WIPP) has been measured to be {\\Phi} = 4.07 $\\pm$ 0.14 (sys) $\\pm$ 0.03 (stat) $\\times$ $10^{-7}$cm$^{-2}$ s$^{-1}$, with a vertical intensity of $I_{v}$ = 2.97$^{+0.14}_{-0.13}$ (sys) $\\pm$ 0.02 (stat) $\\times$ $10^{-7}$cm$^{-2}$ s$^{-1}$ sr$^{-1}$. Simulations of muon-induced backgrounds identified several potential cosmogenic radionuclides, though only 137Xe is a significant background for the 136Xe 0{\

  3. The Cosmic Microwave Background

    Science.gov (United States)

    Pierpaoli, E.

    2011-03-01

    In these lectures I present the physical aspects of the Cosmic Microwave Background primary and secondary anisotropies; the characteristics of the CMB power spectra and their dependence on cosmological parameters. I also discuss the observational status and future perspectives.

  4. Zambia Country Background Report

    DEFF Research Database (Denmark)

    Hampwaye, Godfrey; Jeppesen, Søren; Kragelund, Peter

    This paper provides background data and general information for the Zambia studies focusing on local food processing sub­‐sector; and the local suppliers to the mines as part of the SAFIC project (Successful African Firms and Institutional Change).......This paper provides background data and general information for the Zambia studies focusing on local food processing sub­‐sector; and the local suppliers to the mines as part of the SAFIC project (Successful African Firms and Institutional Change)....

  5. Background Studies for EXIST

    Science.gov (United States)

    Wilson, Colleen A.; Pendleton, G. N.; Fishman, G. J.

    2004-01-01

    We present results from a study of the trapped proton and electron background for several orbital inclinations and altitudes. This study includes time dependent effects. In addition we describe a 3 component cosmic background model developed at the University of Southampton, UK. The three components are cosmic diffuse gamma rays, atmospheric albedo gamma rays, and cosmic ray protons. We present examples of how this model was applied to BATSE and discuss its application to EXIST.

  6. Exploring String Theory Backgrounds

    CERN Document Server

    Williams, B P

    2004-01-01

    This thesis examines phenomenological and theoretical questions by exploring string theoretic backgrounds. Part I focuses on cosmology. First we propose that the induced metric along a brane moving through a curved bulk may be interpreted as the cosmology of the brane universe, providing a resolution to the apparent cosmological singularity on the brane. We then look at various decay channels of the certain meta-stable de Sitter vacua and show that there exist NS5-brane meditated decays which are much faster than decays to decompactification. Part II discusses a new class of nongeometric vacua in string theory. These backgrounds may be described locally as T2 fibrations. By enlarging the monodromy group of the fiber to include perturbative stringy duality symmetries we are able to explicitly construct nongeometric backgrounds.

  7. Cosmic Tachyon Background Radiation

    CERN Document Server

    Tomaschitz, R

    1999-01-01

    The equilibrium statistical mechanics of a background radiation of superluminal particles is investigated, based on a vectorial wave equation for tachyons of the Proca type. The partition function, the spectral energy density, and the various thermodynamic variables of an ideal Bose gas of tachyons in an open Robertson-Walker cosmology are derived. The negative mass square in the wave equation changes the frequency scaling in the Rayleigh-Jeans law, and there are also significant changes in the low temperature regime as compared to the microwave background, in particular in the caloric and thermal equations of state.

  8. The Cosmic Background Explorer

    Science.gov (United States)

    Gulkis, Samuel; Lubin, Philip M.; Meyer, Stephan S.; Silverberg, Robert F.

    1990-01-01

    The Cosmic Background Explorer (CBE), NASA's cosmological satellite which will observe a radiative relic of the big bang, is discussed. The major questions connected to the big bang theory which may be clarified using the CBE are reviewed. The satellite instruments and experiments are described, including the Differential Microwave Radiometer, which measures the difference between microwave radiation emitted from two points on the sky, the Far-Infrared Absolute Spectrophotometer, which compares the spectrum of radiation from the sky at wavelengths from 100 microns to one cm with that from an internal blackbody, and the Diffuse Infrared Background Experiment, which searches for the radiation from the earliest generation of stars.

  9. Cosmic Microwave Background Anisotropies

    OpenAIRE

    Hu, Wayne; Dodelson,Scott

    2001-01-01

    Cosmic microwave background (CMB) temperature anisotropies have and will continue to revolutionize our understanding of cosmology. The recent discovery of the previously predicted acoustic peaks in the power spectrum has established a working cosmological model: a critical density universe consisting of mainly dark matter and dark energy, which formed its structure through gravitational instability from quantum fluctuations during an inflationary epoch. Future observations should test this mo...

  10. Sri Lanka; Background Papers

    OpenAIRE

    International Monetary Fund

    1995-01-01

    This Background Paper on Sri Lanka provides information on the economic developments during 1992–95. Developments in the domestic and external sectors are discussed. The deficiencies of the official consumer price index that resulted in a substantial understatement of inflation performance in 1994 and alternative estimates of underlying inflation are described. The structural rigidities in the labor market that perpetuate high unemployment and limit job growth are also described. The paper al...

  11. Reduction of background by higher order statistics with NMIS

    Energy Technology Data Exchange (ETDEWEB)

    Mattingly, jk; Mullens, ja; Mihalczo, jt

    2000-07-11

    Measurements that accumulate the rate of real coincidence between multiplets of detection events (groupings of arbitrary order, e.g., one event, two events, three events, etc.) can yield spurious results if background events arise from processes (e.g., spontaneous fission or neutron spallation) that themselves produce correlated multiplets. This is particularly true if this background varies significantly over time or from one location to another, as it often does in operating facilities, i.e., those not specifically designed to support experimental radiation measurements but that instead rely upon the support of precise radiation measurements for, e.g., NMC and A. In particular, both the quantity and location of radioactive material in weapons facilities changes frequently and unpredictably, and so the background due to the presence (or absence) of this material is completely out of the control of the radiation measurement analyst. Furthermore, numerous Nuclear Materials Identification System (NMIS) measurements have revealed that background often contains mutually correlated events even in the complete absence of material (e.g., {sup 240}Pu) with a significant spontaneous fission rate. The technique subsequently described removes the effects of such self-correlated background from active NMIS measurements. It could be adapted to other active radiation measurements.

  12. Family Background and Entrepreneurship

    DEFF Research Database (Denmark)

    Lindquist, Matthew J.; Sol, Joeri; Van Praag, Mirjam

    Vast amounts of money are currently being spent on policies aimed at promoting entrepreneurship. The success of such policies, however, rests in part on the assumption that individuals are not ‘born entrepreneurs’. In this paper, we assess the importance of family background and neighborhood...... treatment within families by gender and birth order does little to further increase our estimates of the importance of family-wide factors. We then go on to show that neighborhood effects, sibling peer effects, and parental income and education explain very little of these correlations. Parental...

  13. Background and introduction

    DEFF Research Database (Denmark)

    Jensen, Per Anker; van der Voordt, Theo; Coenen, Christian

    2012-01-01

    Purpose: To explain the purpose and background of this book and introduce the three basic perspectives behind the research presented as well as the structure and editing process of the book. Methodology: The editors shared and discussed individual contributions to this chapter, based on their own...... behind the scenes of the making of this book and connects contributions from three different fields - FM, CREM, and B2B marketing - to shed more light on the concept of added value of FM. It serves as an introduction to the research presented in the other chapters in this book....

  14. Cosmic Background Radiation

    Science.gov (United States)

    Sidharth, B. G.; Valluri, S. R.

    2015-08-01

    It is shown that a collection of photons with nearly the same frequency exhibits a "condensation" type of phenomenon corresponding to a peak intensity. The observed cosmic background radiation can be explained from this standpoint. We have obtained analogous results by extremization of the occupation number for photons with the use of the Lambert W function. Some of the interesting applications of this function are briefly discussed in the context of graphene which exhibits an interesting two dimensional structure with several characteristic properties and diverse practical applications.

  15. Malaysia; Background Paper

    OpenAIRE

    International Monetary Fund

    1996-01-01

    This Background Paper on Malaysia examines developments and trends in the labor market since the mid-1980s. The paper describes the changes in the employment structure and the labor force. It reviews wages and productivity trends and their effects on unit labor cost. The paper highlights that Malaysia’s rapid growth, sustained since 1987, has had a major impact on the labor market. The paper outlines the major policy measures to address the labor constraints. It also analyzes Malaysia’s recen...

  16. Genetical background of intelligence

    Directory of Open Access Journals (Sweden)

    Anna Junkiert-Czarnecka

    2016-06-01

    Full Text Available Intelligence as an ability to reason, think abstractly and adapt effectively to the environment is a subject of research in the field of psychology, neurobiology, and in the last twenty years genetics as well. Genetical testing of twins carried out from XX century indicated heritebility of intelligence, therefore confirmed an influence of genetic factor on cognitive processes. Studies on genetic background of intelligence focus on dopaminergic (DRD2, DRD4, COMT, SLC6A3, DAT1, CCKAR and adrenergic system (ADRB2, CHRM2 genes as well as, neutrofins (BDNF and oxidative stress genes (LTF, PRNP. Positive effect of investigated gene polymorphism was indicated by variation c.957C>T DRD2 gene (if in polymorphic site is thymine, polymorphism c.472G>A COMT gene (presence of adenine and also gene ADRB2 c.46A->G (guanine, CHRM2 (thymine in place c.1890A>T and BDNF (guanine in place c.472G>A Obtained results indicate that intelligence is a feature dependent not only on genetic but also an environmental factor.

  17. Genetical background of intelligence.

    Science.gov (United States)

    Junkiert-Czarnecka, Anna; Haus, Olga

    2016-06-13

    Intelligence as an ability to reason, think abstractly and adapt effectively to the environment is a subject of research in the field of psychology, neurobiology, and in the last twenty years genetics as well. Genetical testing of twins carried out from XX century indicated heritebility of intelligence, therefore confirmed an influence of genetic factor on cognitive processes. Studies on genetic background of intelligence focus on dopaminergic (DRD2, DRD4, COMT, SLC6A3, DAT1, CCKAR) and adrenergic system (ADRB2, CHRM2) genes as well as, neutrofins (BDNF) and oxidative stress genes (LTF, PRNP). Positive effect of investigated gene polymorphism was indicated by variation c.957C>T DRD2 gene (if in polymorphic site is thymine), polymorphism c.472G>A COMT gene (presence of adenine) and also gene ADRB2 c.46A->G (guanine), CHRM2 (thymine in place c.1890A>T) and BDNF (guanine in place c.472G>A) Obtained results indicate that intelligence is a feature dependent not only on genetic but also an environmental factor.

  18. Background paper on aquaculture research

    DEFF Research Database (Denmark)

    Wenblad, Axel; Jokumsen, Alfred; Eskelinen, Unto

    The Board of MISTRA established in 2012 a Working Group (WG) on Aquaculture to provide the Board with background information for its upcoming decision on whether the foundation should invest in aquaculture research. The WG included Senior Advisor Axel Wenblad, Sweden (Chairman), Professor Ole...... due to the availability of vast water resources of good quality (both marine and fresh water), a high veterinary status and generally well developed public infrastructure. Swedish aquaculture has the potential to develop into a green business producing environmentally sustainable healthy food with low...... of adequate funding from national and international sources (e.g. EMFF, research councils, EU, Nordic and BONUS). Finally, the financial sector should be made more confident with aquaculture to facilitate investments in aquaculture. The integration of environmental, economic and social sustainability...

  19. Optical polarization: background and camouflage

    Science.gov (United States)

    Škerlind, Christina; Hallberg, Tomas; Eriksson, Johan; Kariis, Hans; Bergström, David

    2017-10-01

    Polarimetric imaging sensors in the electro-optical region, already military and commercially available in both the visual and infrared, show enhanced capabilities for advanced target detection and recognition. The capabilities arise due to the ability to discriminate between man-made and natural background surfaces using the polarization information of light. In the development of materials for signature management in the visible and infrared wavelength regions, different criteria need to be met to fulfil the requirements for a good camouflage against modern sensors. In conventional camouflage design, the aimed design of the surface properties of an object is to spectrally match or adapt it to a background and thereby minimizing the contrast given by a specific threat sensor. Examples will be shown from measurements of some relevant materials and how they in different ways affect the polarimetric signature. Dimensioning properties relevant in an optical camouflage from a polarimetric perspective, such as degree of polarization, the viewing or incident angle, and amount of diffuse reflection, mainly in the infrared region, will be discussed.

  20. Low background infrared (LBIR) facility

    Data.gov (United States)

    Federal Laboratory Consortium — The Low background infrared (LBIR) facility was originally designed to calibrate user supplied blackbody sources and to characterize low-background IR detectors and...

  1. Ablation plume dynamics in a background gas

    DEFF Research Database (Denmark)

    Amoruso, Salvatore; Schou, Jørgen; Lunney, James G.

    2010-01-01

    the expansion. The model also leads to an insightful treatment of the stopping behavior in dimensionless units for plumes and background gases of different atomic/molecular masses. The energetics of the plume dynamics can also be treated with this model. Experimental time-of-flight data of silver ions in a neon...

  2. Background Assay and Rejection in DRIFT

    OpenAIRE

    Brack, J.; Daw, E.; Dorofeev, A.; Ezeribe, A.; Gauvreau, J. -L.; Gold, M; Harton, J.; Lafler, R.; Lauer, R.; Lee, E.R.; Loomba, D.; Matthews, J.; Miller, E. H.; Monte, A; Murphy, A

    2015-01-01

    The DRIFT-IId dark matter detector is a m$^3$-scale low-pressure TPC with directional sensitivity to WIMP-induced nuclear recoils. Its primary backgrounds were due to alpha decays from contamination on the central cathode. Efforts to reduce these backgrounds led to replacing the 20 \\mu m wire central cathode with one constructed from 0.9 \\mu m aluminized mylar, which is almost totally transparent to alpha particles. Detailed modeling of the nature and origin of the remaining backgrounds led t...

  3. JEM-X background models

    DEFF Research Database (Denmark)

    Huovelin, J.; Maisala, S.; Schultz, J.

    2003-01-01

    Background and determination of its components for the JEM-X X-ray telescope on INTEGRAL are discussed. A part of the first background observations by JEM-X are analysed and results are compared to predictions. The observations are based on extensive imaging of background near the Crab Nebula...... on revolution 41 of INTEGRAL. Total observing time used for the analysis was 216 502 s, with the average of 25 cps of background for each of the two JEM-X telescopes. JEM-X1 showed slightly higher average background intensity than JEM-X2. The detectors were stable during the long exposures, and weak orbital...... phase dependence in the background outside radiation belts was observed. The analysis yielded an average of 5 cps for the diffuse background, and 20 cps for the instrument background. The instrument background was found highly dependent on position, both for spectral shape and intensity. Diff use...

  4. Marginal Aggregates in Flexible Pavements: Background Survey and Experimental Plan

    Science.gov (United States)

    1994-08-01

    in a pavement base course. Geotextile reinforcement and a new portland cement- bitumen emulsion have considerable potential to upgrade substandard...stabilization instead of portland cement because of slower setting and strength gain, reduced shrinkage, and lower cost’. Recently, an emulsion of portland...cement, bitumen , and water has been marketed in France under the trade name Stabicol 71 , but it is not yet available in the U.S. This composite

  5. Beam induced backgrounds: CDF experience

    Energy Technology Data Exchange (ETDEWEB)

    Tesarek, R.J.; /Fermilab

    2008-05-01

    We summarize the experiences of the Collider Detector at Fermilab (CDF) experiment in the presence of backgrounds originating from the counter circulating beams in the Fermilab Tevatron. These backgrounds are measured and their sources identified. Finally, we outline the strategies employed to reduce the effects of these backgrounds on the experiment.

  6. Backgrounder

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Researchers from Costa Rica's Facultad Latinoamericana de Ciencias Sociales will examine why urban communities with similar conditions of social exclusion experience different levels of violence. The study will compare six cities of different sizes in Costa Rica and El Salvador. • The Centro de Estudios en Seguridad ...

  7. BACKGROUNDER

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Through this initiative, four consortia will conduct research in three “hot spots” – regions where demographic trends, socio-economic development pathways, and strong climate signals put large numbers of people and their livelihoods at risk: semi-arid regions, deltas, and Himalayan river basins. The initiative brings ...

  8. BACKGROUNDER

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Through this initiative, four consortia will conduct research in three types of “hot spots” – regions where demographic trends and strong climate signals put large numbers of people and their livelihoods at risk: semi-arid regions, deltas, and Himalayan river basins. The initiative brings together experts from a variety of ...

  9. BACKGROUNDER

    International Development Research Centre (IDRC) Digital Library (Canada)

    Corey Piccioni

    Poor water availability, access, and management are constraining food output. Many small‐scale farmers operate with dryland farming systems and experience limited and uncertain rainfall. Major new dams do not provide feasible opons for most of these farmers. Instead they rely on shallow groundwater, rivers, lakes, and ...

  10. Backgrounder

    International Development Research Centre (IDRC) Digital Library (Canada)

    IDRC CRDI

    Agua Sustentable, Bolivia: $1,077,600 to strengthen local ability to cope and adapt to climate change in the. Bolivian Altiplano. • Centro de Cambio Global, Pontificia Universidad Católica de Chile, Chile: $1,298,000 for research on vulnerability and adaptation to climate change and variability in the Maipo Basin of central ...

  11. Influence of Background Patterns in the Reverse Perspective Illusion

    Directory of Open Access Journals (Sweden)

    Takefumi Hayashi

    2011-05-01

    Full Text Available The reverse perspective (RP illusion is classified as a motion illusion due to inverted depth perception, similar to the Mach book and hollow mask illusions. Distortional motion of a rigid object surface is observed when an observer moves in front of the object which has a texture pattern giving inverted perspective cues (RP object. In this research, we studied the influence of the background pattern of the RP objects on the strength of the illusion. To perform quantitative evaluation, a stereo computer-graphics technique was used. Computer generated right- and left-eye images of an RP object were shown separately to the subjects' eyes through a haploscope. Using a computer key board, they adjusted the binocular disparity of the stereo images so that depth inversion due to the surface texture occurs. We evaluated the strength of the illusion by the critical value of the disparity and found that the background texture is an important factor determining the strength of the RP illusion. Especially, the texture in the horizontal direction creates stronger depth inversion effect compared to the vertical pattern. Using our experimental system, the influences of various pictorial cues on the RP illusion can be studied quantitatively.

  12. Extragalactic background light measurements and applications

    Science.gov (United States)

    Cooray, Asantha

    2016-01-01

    This review covers the measurements related to the extragalactic background light intensity from γ-rays to radio in the electromagnetic spectrum over 20 decades in wavelength. The cosmic microwave background (CMB) remains the best measured spectrum with an accuracy better than 1%. The measurements related to the cosmic optical background (COB), centred at 1 μm, are impacted by the large zodiacal light associated with interplanetary dust in the inner Solar System. The best measurements of COB come from an indirect technique involving γ-ray spectra of bright blazars with an absorption feature resulting from pair-production off of COB photons. The cosmic infrared background (CIB) peaking at around 100 μm established an energetically important background with an intensity comparable to the optical background. This discovery paved the way for large aperture far-infrared and sub-millimetre observations resulting in the discovery of dusty, starbursting galaxies. Their role in galaxy formation and evolution remains an active area of research in modern-day astrophysics. The extreme UV (EUV) background remains mostly unexplored and will be a challenge to measure due to the high Galactic background and absorption of extragalactic photons by the intergalactic medium at these EUV/soft X-ray energies. We also summarize our understanding of the spatial anisotropies and angular power spectra of intensity fluctuations. We motivate a precise direct measurement of the COB between 0.1 and 5 μm using a small aperture telescope observing either from the outer Solar System, at distances of 5 AU or more, or out of the ecliptic plane. Other future applications include improving our understanding of the background at TeV energies and spectral distortions of CMB and CIB. PMID:27069645

  13. Background voltage distortion influence on power electric systems in the presence of the Steinmetz circuit

    Energy Technology Data Exchange (ETDEWEB)

    Sainz, Luis; Pedra, Joaquin [Department of Electrical Engineering, ETSEIB-UPC, Av. Diagonal 647, 08028 Barcelona (Spain); Caro, Manuel [IDOM Ingenieria y Arquitectura, C. Barcas 2, 46002 Valencia (Spain)

    2009-01-15

    In traction systems, it is usual to connect reactances in delta configuration with single-phase loads to reduce voltage unbalances and avoid electric system operation problems. This set is known as Steinmetz circuit. Parallel and series resonances can occur due to the capacitive reactance of the Steinmetz circuit and affect power quality. In this paper, the series resonance ''observed'' from the supply system is numerically located. The study of this resonance is important to avoid problems due to background voltage distortion. Experimental measurements are also presented to validate the obtained numerical results. (author)

  14. Parental Background and Union Formation Behavior of Native Born Individuals in Sweden with a Foreign Background

    Directory of Open Access Journals (Sweden)

    Aycan Çelikaksoy

    2014-06-01

    Full Text Available Social cohesion in destination countries is an increasingly important issue due to the multiethnic structures in these countries and due to ongoing international migration. Union formation of individuals across different backgrounds can be seen as an indicator of social cohesion. However, this phenomenon is important not only in the case of first generation migrants but also for their descendants. Thus, this paper analyzes the determinants of intergroup union formation patterns of the native born individuals with a foreign background focusing on the role of parental background in addition to individual as well as marriage market characteristics. High quality data at the individual level, from Statistics Sweden, for the whole population of interest is utilized. The results indicate that parental composition is an important determinant of union formation behavior. Furthermore, there are gender specific pathways of the parental background effects.

  15. Erratum to: Music listening while you learn: No influence of background music on verbal learning

    National Research Council Canada - National Science Library

    Lutz Jancke; Pascale Sandmann

    2010-01-01

    ... (800 - 1200 ms and 1600 - 2000 ms after word presentation). Left: Mean ERD for the five experimental groups broken down for learning with (background+ in red) and without (background- in blue) background music. Right...

  16. Non-collision backgrounds in ATLAS

    CERN Document Server

    Gibson, S M; The ATLAS collaboration

    2012-01-01

    The proton-proton collision events recorded by the ATLAS experiment are on top of a background that is due to both collision debris and non-collision components. The latter comprises of three types: beam-induced backgrounds, cosmic particles and detector noise. We present studies that focus on the first two of these. We give a detailed description of beam-related and cosmic backgrounds based on the full 2011 ATLAS data set, and present their rates throughout the whole data-taking period. Studies of correlations between tertiary proton halo and muon backgrounds, as well as, residual pressure and resulting beam-gas events seen in beam-condition monitors will be presented. Results of simulations based on the LHC geometry and its parameters will be presented. They help to better understand the features of beam-induced backgrounds in each ATLAS sub-detector. The studies of beam-induced backgrounds in ATLAS reveal their characteristics and serve as a basis for designing rejection tools that can be applied in physic...

  17. Background subtraction theory and practice

    CERN Document Server

    Elgammal, Ahmed

    2014-01-01

    Background subtraction is a widely used concept for detection of moving objects in videos. In the last two decades there has been a lot of development in designing algorithms for background subtraction, as well as wide use of these algorithms in various important applications, such as visual surveillance, sports video analysis, motion capture, etc. Various statistical approaches have been proposed to model scene backgrounds. The concept of background subtraction also has been extended to detect objects from videos captured from moving cameras. This book reviews the concept and practice of back

  18. Proton-induced background in LEGRI

    Science.gov (United States)

    Porras, E.; Sánchez, F.; Lei, F.; Pérez, J. M.; Reglero, V.; Dean, A. J.

    The Low Energy Gamma Ray Imager (LEGRI) on board the Spanish MINISAT-01 mission is a position-sensitive γ-ray instrument with a 10 × 10 HgI2 elements array on the detector plane. This telescope is dedicated to imaging of astrophysical sources in the 20-200 keV spectral range. In the framework of LEGRI sensitivity evaluations, one of the focal points is the determination of the background noise induced by the cosmic and trapped proton flux. To achieve an accurate estimation of this background noise component, small HgI2 crystals were irradiated with high energy protons at SATURNE (Saclay, France). After the identification of the unstable isotopes generated by the proton flux, their production rates were calculated. The experimental data were compared with the results obtained by a Monte Carlo simulation code. Since a good agreement between both experimental and simulation results was observed, these last ones have been used to perform full calculations of the proton-induced background in LEGRI. The information provided by these calculations has been used to estimate an upper limit of LEGRI sensitivity.

  19. Visual signal detection in structured backgrounds. II. Effects of contrast gain control, background variations, and white noise

    Science.gov (United States)

    Eckstein, M. P.; Ahumada, A. J. Jr; Watson, A. B.

    1997-01-01

    Studies of visual detection of a signal superimposed on one of two identical backgrounds show performance degradation when the background has high contrast and is similar in spatial frequency and/or orientation to the signal. To account for this finding, models include a contrast gain control mechanism that pools activity across spatial frequency, orientation and space to inhibit (divisively) the response of the receptor sensitive to the signal. In tasks in which the observer has to detect a known signal added to one of M different backgrounds grounds due to added visual noise, the main sources of degradation are the stochastic noise in the image and the suboptimal visual processing. We investigate how these two sources of degradation (contrast gain control and variations in the background) interact in a task in which the signal is embedded in one of M locations in a complex spatially varying background (structured background). We use backgrounds extracted from patient digital medical images. To isolate effects of the fixed deterministic background (the contrast gain control) from the effects of the background variations, we conduct detection experiments with three different background conditions: (1) uniform background, (2) a repeated sample of structured background, and (3) different samples of structured background. Results show that human visual detection degrades from the uniform background condition to the repeated background condition and degrades even further in the different backgrounds condition. These results suggest that both the contrast gain control mechanism and the background random variations degrade human performance in detection of a signal in a complex, spatially varying background. A filter model and added white noise are used to generate estimates of sampling efficiencies, an equivalent internal noise, an equivalent contrast-gain-control-induced noise, and an equivalent noise due to the variations in the structured background.

  20. Berkeley Low Background Counting Facility

    Data.gov (United States)

    Federal Laboratory Consortium — Sensitive low background assay detectors and sample analysis are available for non-destructive direct gamma-ray assay of samples. Neutron activation analysis is also...

  1. Backgrounds in AFP Detector Estimation

    CERN Document Server

    Huang, Yicong

    2016-01-01

    The ATLAS Forward Proton (AFP) detectors aim to measure protons that are scattered in the ATLAS interaction point under very small angles ($90-160 \\mu rad$). The diffractive protons detected by the AFP may be accompanied by beam halo. This report presents an estimation of the beam halo backgrounds in the AFP using low pile-up data, and position distributions of the backgrounds in the AFP.

  2. Cosmic microwave background, where next?

    CERN Multimedia

    CERN. Geneva

    2009-01-01

    Ground-based, balloon-borne and space-based experiments will observe the Cosmic Microwave Background in greater details to address open questions about the origin and the evolution of the Universe. In particular, detailed observations the polarization pattern of the Cosmic Microwave Background radiation have the potential to directly probe physics at the GUT scale and illuminate aspects of the physics of the very early Universe.

  3. Neutron background estimates in GESA

    Directory of Open Access Journals (Sweden)

    Fernandes A.C.

    2014-01-01

    Full Text Available The SIMPLE project looks for nuclear recoil events generated by rare dark matter scattering interactions. Nuclear recoils are also produced by more prevalent cosmogenic neutron interactions. While the rock overburden shields against (μ,n neutrons to below 10−8 cm−2 s−1, it itself contributes via radio-impurities. Additional shielding of these is similar, both suppressing and contributing neutrons. We report on the Monte Carlo (MCNP estimation of the on-detector neutron backgrounds for the SIMPLE experiment located in the GESA facility of the Laboratoire Souterrain à Bas Bruit, and its use in defining additional shielding for measurements which have led to a reduction in the extrinsic neutron background to ∼ 5 × 10−3 evts/kgd. The calculated event rate induced by the neutron background is ∼ 0,3 evts/kgd, with a dominant contribution from the detector container.

  4. Background music and cognitive performance.

    Science.gov (United States)

    Angel, Leslie A; Polzella, Donald J; Elvers, Greg C

    2010-06-01

    The present experiment employed standardized test batteries to assess the effects of fast-tempo music on cognitive performance among 56 male and female university students. A linguistic processing task and a spatial processing task were selected from the Criterion Task Set developed to assess verbal and nonverbal performance. Ten excerpts from Mozart's music matched for tempo were selected. Background music increased the speed of spatial processing and the accuracy of linguistic processing. The findings suggest that background music can have predictable effects on cognitive performance.

  5. Generative electronic background music system

    Energy Technology Data Exchange (ETDEWEB)

    Mazurowski, Lukasz [Faculty of Computer Science, West Pomeranian University of Technology in Szczecin, Zolnierska Street 49, Szczecin, PL (Poland)

    2015-03-10

    In this short paper-extended abstract the new approach to generation of electronic background music has been presented. The Generative Electronic Background Music System (GEBMS) has been located between other related approaches within the musical algorithm positioning framework proposed by Woller et al. The music composition process is performed by a number of mini-models parameterized by further described properties. The mini-models generate fragments of musical patterns used in output composition. Musical pattern and output generation are controlled by container for the mini-models - a host-model. General mechanism has been presented including the example of the synthesized output compositions.

  6. Fundamentals of Experimental Pharmacology

    National Research Council Canada - National Science Library

    Ghosh, M

    2007-01-01

    ... to its unique approach in comparison to other books available on Experimental pharmacology. The main purpose of this book was to give a theoretical background followed by the appropriate experimental techniques. The late Prof. H. O. Schild, then Professor of Pharmacology, University College London in his brief introduction to the first editi...

  7. Measurements of background radiation at LAFN

    Energy Technology Data Exchange (ETDEWEB)

    Rodrigues, A.V.G.A.; Medina, N.H.; Seale, W.A.; Oliveira, J.B.R.; Cybulska, E.W.; Ribas, R.V. [Universidade de Sao Paulo, SP (Brazil). Inst. de Fisica

    2001-07-01

    The background gamma radiation at four sites in the 'Laboratorio Aberto de Fisica Nuclear (LAFN) at the Instituto de Fisica of the Universidade de Sao Paulo was measured with a GeHP detector with an efficiency of 20% and a resolution of 2.5 keV. This detector was coupled to conventional electronics connected to a computer which stored the gamma ray spectra. The four sites were: the control room of the Pelletron accelerator; near the 30 deg A, and 45 deg B beam lines of the experimental room of the Pelletron accelerator; and the experimental room of the Linac accelerator. For each of the four locations, the data were accumulated, on average, during one week. Gamma rays from the radioactive series of {sup 238} U, {sup 235} U and {sup 232} Th have been observed. Another important element observed in background radiation was {sup 40} K, very common in soil and in construction materials. The analysis of the data showed no significant differences among the four site locations, except for an increase of the 661-keV gamma ray line from {sup 137} Cs, near the 30 deg A beam line. After a careful search, a few fragments of the capsule of a calibration source were found. The fragments were collected and the total source strength was measured to be 29.0(2)kBq. (author)

  8. Cultural Backgrounds and Textual Appropriation

    Science.gov (United States)

    Shi, Ling

    2006-01-01

    This study examines interviews with 46 undergraduates to explore if participants with differing language and cultural backgrounds view plagiarism or textual appropriation primarily as a) a language problem because of a lack of words of one's own, or b) a cultural challenge as a result of either some first language (L1) cultural training to…

  9. Family Background and Educational Choices

    DEFF Research Database (Denmark)

    McIntosh, James; D. Munk, Martin

    enrollments, especially for females. Not only did the educational opportunities for individuals with disadvantaged backgrounds improve absolutely, but their relative position also improved. A similarly dramatic increase in attendance at university for the period 1985-2005 was found for these cohorts when...

  10. Low Background Micromegas in CAST

    CERN Document Server

    Garza, J.G.; Aznar, F.; Calvet, D.; Castel, J.F.; Christensen, F.E.; Dafni, T.; Davenport, M.; Decker, T.; Ferrer-Ribas, E.; Galán, J.; García, J.A.; Giomataris, I.; Hill, R.M.; Iguaz, F.J.; Irastorza, I.G.; Jakobsen, A.C.; Jourde, D.; Mirallas, H.; Ortega, I.; Papaevangelou, T.; Pivovaroff, M.J.; Ruz, J.; Tomás, A.; Vafeiadis, T.; Vogel, J.K.

    2015-11-16

    Solar axions could be converted into x-rays inside the strong magnetic field of an axion helioscope, triggering the detection of this elusive particle. Low background x-ray detectors are an essential component for the sensitivity of these searches. We report on the latest developments of the Micromegas detectors for the CERN Axion Solar Telescope (CAST), including technological pathfinder activities for the future International Axion Observatory (IAXO). The use of low background techniques and the application of discrimination algorithms based on the high granularity of the readout have led to background levels below 10$^{-6}$ counts/keV/cm$^2$/s, more than a factor 100 lower than the first generation of Micromegas detectors. The best levels achieved at the Canfranc Underground Laboratory (LSC) are as low as 10$^{-7}$ counts/keV/cm$^2$/s, showing good prospects for the application of this technology in IAXO. The current background model, based on underground and surface measurements, is presented, as well as ...

  11. Low Background Micromegas in CAST

    DEFF Research Database (Denmark)

    Garza, J G; Aune, S.; Aznar, F.

    2014-01-01

    of the Micromegas detectors for the CERN Axion Solar Telescope (CAST), including technological pathfinder activities for the future International Axion Observatory (IAXO). The use of low background techniques and the application of discrimination algorithms based on the high granularity of the readout have led...

  12. Teaching about Natural Background Radiation

    Science.gov (United States)

    Al-Azmi, Darwish; Karunakara, N.; Mustapha, Amidu O.

    2013-01-01

    Ambient gamma dose rates in air were measured at different locations (indoors and outdoors) to demonstrate the ubiquitous nature of natural background radiation in the environment and to show that levels vary from one location to another, depending on the underlying geology. The effect of a lead shield on a gamma radiation field was also…

  13. Cultural Change. Teacher Background Material.

    Science.gov (United States)

    Georgia Univ., Athens. Anthropology Curriculum Project.

    This essay on cultural change is intended to provide background reading material for teachers using "The Changing World Today" or "Cultural Change in Mexico and the United States," two textbooks from the Anthropology Curriculum Project. The essay can also be used, however, as a high school semester course in anthropology or as…

  14. Low background techniques in CANDLES

    Energy Technology Data Exchange (ETDEWEB)

    Nakajima, K., E-mail: kyohei@rcnp.osaka-u.ac.jp, E-mail: nkyohei@u-fukui.ac.jp [Research Center for Nuclear Physics, Osaka University, Ibaraki, Osaka 567-0047 (Japan); Graduate School of Engineering, University of Fukui, Fukui 910-8507 (Japan); Iida, T.; Matsuoka, K.; Nomachi, M.; Umehara, S. [Research Center for Nuclear Physics, Osaka University, Ibaraki, Osaka 567-0047 (Japan); Kishimoto, T. [Research Center for Nuclear Physics, Osaka University, Ibaraki, Osaka 567-0047 (Japan); Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 (Japan); Chan, W. M.; Kakubata, H.; Li, X.; Maeda, T.; Ohata, T.; Temuge, B.; Tetsuno, K.; Trang, V. T. T.; Uehara, T.; Yoshida, S. [Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043 (Japan); Morishita, K.; Ogawa, I.; Sakamoto, K.; Tamagawa, Y. [Graduate School of Engineering, University of Fukui, Fukui 910-8507 (Japan); and others

    2015-08-17

    CANDLES is a double beta decay experiment using {sup 48}Ca in CaF{sub 2} crystals. The measurement is being performed with prototype detector (CANDLES III) for high sensitive measurement in the future. Recent status of detector improvements and background reduction techniques are described in this paper.

  15. Cosmogenesis backgrounds, experiment depth and the solar neutrino TPC

    Science.gov (United States)

    Bonvicini, G.; Schreiner, A.

    2002-11-01

    A Time Projection Chamber (TPC) is one of the promising candidates to perform unique measurements in solar neutrino physics. Its features will enable it to work at depths of the order of 2000 mwe. This paper describes an estimation of the expected cosmogenic background at different depths including also the background due to fission activation of the TPC material above ground.

  16. Cosmogenesis Backgrounds, Experiment Depth and the Solar Neutrino TPC

    CERN Document Server

    Bonvicini, G

    2002-01-01

    A Time Projection Chamber (TPC) is one of the promising candidates to perform unique measurements in solar neutrino physics. Its features will enable it to work at depths of the order of 2000 mwe. This paper describes an estimation of the expected cosmogenic background at different depths including also the background due to fission activation of the TPC material above ground.

  17. 32 CFR 525.2 - Background and authority.

    Science.gov (United States)

    2010-07-01

    ... authority. (a) Background. (1) Certain areas, due to their strategic nature or for purposes of defense, have... regulations. Such restrictions are imposed for defense purposes because of the unique strategic nature of the... 32 National Defense 3 2010-07-01 2010-07-01 true Background and authority. 525.2 Section 525.2...

  18. Muon background studies for shallow depth Double - Chooz near detector

    Energy Technology Data Exchange (ETDEWEB)

    Gómez, H. [Laboratoire Astroparticule et Cosmologie (APC) - Université Paris 7. Paris (France)

    2015-08-17

    Muon events are one of the main concerns regarding background in neutrino experiments. The placement of experimental set-ups in deep underground facilities reduce considerably their impact on the research of the expected signals. But in the cases where the detector is installed on surface or at shallow depth, muon flux remains high, being necessary their precise identification for further rejection. Total flux, mean energy or angular distributions are some of the parameters that can help to characterize the muons. Empirically, the muon rate can be measured in an experiment by a number of methods. Nevertheless, the capability to determine the muons angular distribution strongly depends on the detector features, while the measurement of the muon energy is quite difficult. Also considering that on-site measurements can not be extrapolated to other sites due to the difference on the overburden and its profile, it is necessary to find an adequate solution to perform the muon characterization. The method described in this work to obtain the main features of the muons reaching the experimental set-up, is based on the muon transport simulation by the MUSIC software, combined with a dedicated sampling algorithm for shallow depth installations based on a modified Gaisser parametrization. This method provides all the required information about the muons for any shallow depth installation if the corresponding overburden profile is implemented. In this work, the method has been applied for the recently commissioned Double - Chooz near detector, which will allow the cross-check between the simulation and the experimental data, as it has been done for the far detector.

  19. Background stratospheric aerosol reference model

    Science.gov (United States)

    Mccormick, M. P.; Wang, P.

    1989-01-01

    In this analysis, a reference background stratospheric aerosol optical model is developed based on the nearly global SAGE 1 satellite observations in the non-volcanic period from March 1979 to February 1980. Zonally averaged profiles of the 1.0 micron aerosol extinction for the tropics and the mid- and high-altitudes for both hemispheres are obtained and presented in graphical and tabulated form for the different seasons. In addition, analytic expressions for these seasonal global zonal means, as well as the yearly global mean, are determined according to a third order polynomial fit to the vertical profile data set. This proposed background stratospheric aerosol model can be useful in modeling studies of stratospheric aerosols and for simulations of atmospheric radiative transfer and radiance calculations in atmospheric remote sensing.

  20. Estimating COCOM Natural Background Dormancy

    Science.gov (United States)

    2015-04-01

    affected by the location and the types of vegetation being as- sessed. Hmimina et al. (2013) found that among five biomes —temperate deciduous forests ...distribution is unlimited. Cover photo: upper left, verdant deciduous trees, White Mountain Forest , New...brown, forest green, and partly white, the latter consisting of white and the local background color. The atlas contains 72 maps: 12 monthly maps

  1. Comparing Cosmic Microwave Background Datasets

    OpenAIRE

    Knox, L.; Bond, J..R.; Jaffe, A. H.; Segal, M; Charbonneau, D

    1998-01-01

    To extract reliable cosmic parameters from cosmic microwave background datasets, it is essential to show that the data are not contaminated by residual non-cosmological signals. We describe general statistical approaches to this problem, with an emphasis on the case in which there are two datasets that can be checked for consistency. A first visual step is the Wiener filter mapping from one set of data onto the pixel basis of another. For more quantitative analyses we develop and apply both B...

  2. Particle propagation in cosmological backgrounds

    CERN Document Server

    Arteaga, Daniel

    2007-01-01

    We study the quantum propagation of particles in cosmological backgrounds, by considering a doublet of massive scalar fields propagating in an expanding universe, possibly filled with radiation. We focus on the dissipative effects related to the expansion rate. At first order, we recover the expected result that the decay rate is determined by the local temperature. Beyond linear order, the decay rate has an additional contribution governed by the expansion parameter. This latter contribution is present even for stable particles in the vacuum. Finally, we analyze the long time behaviour of the propagator and briefly discuss applications to the trans-Planckian question.

  3. [Toothache with a neuropathic background].

    Science.gov (United States)

    Khatchaturian, V; de Wijer, A; Kalaykova, S I; Steenks, M H

    2015-03-01

    A 48-year old woman in good general health was referred to the orofacial pain clinic in a centre for special dentistry with a toothache in the premolar region of the left maxillary quadrant. The complaints had existed for 15 years and various dental treatments, including endodontic treatments, apical surgery, extraction and splint therapy, had not helped to alleviate the complaints. As a result of the fact that anti-epileptic drugs were able to reduce the pain it was concluded that this 'toothache' satisfied the criteria of an atypical odontalgia: 'toothache' with a neuropathic background.

  4. Immunopathogenic Background of Pars Planitis.

    Science.gov (United States)

    Przeździecka-Dołyk, Joanna; Węgrzyn, Agnieszka; Turno-Kręcicka, Anna; Misiuk-Hojło, Marta

    2016-04-01

    Pars planitis is defined as an intermediate uveitis of unknown background of systemic disease with characteristic formations such as vitreous snowballs, snowbanks and changes in peripheral retina. The incidence of pars planitis varies 2.4-15.4 % of the uveitis patients. The pathogenesis of the disease is to be determined in future. Clinical and histopathological findings suggest an autoimmune etiology, most likely as a reaction to endogenous antigen of unknown source, with T cells predominant in both vitreous and pars plana infiltrations. T cells subsets play an important role as a memory-effector peripheral cell. Snowbanks are formed as an effect of post inflammatory glial proliferation of fibrous astrocytes. There is also a genetic predisposition for pars planitis by human leukocyte antigen and several other genes. A coexistence of multiple sclerosis and optic neuritis has been described in numerous studies. Epiretinal membrane, cataract, cystoid macular edema, retinal detachment, retinal vasculitis, neovascularization, vitreous peripheral traction, peripheral hole formation, vitreous hemorrhage, disc edema are common complications observed in pars planitis. There is a need to expand the knowledge of the pathogenic and immunologic background of the pars planitis to create an accurate pharmacological treatment.

  5. Sharp Reduction in Black Child Poverty Due to Welfare Reform. The Heritage Foundation Backgrounder.

    Science.gov (United States)

    Pardue, Melissa G.

    This report asserts that welfare reform has been very successful in reducing child poverty. For a quarter-century prior to reform, black child poverty and poverty among single mothers remained virtually constant. Six years after reform, poverty among both groups dropped rapidly, reaching the lowest levels in U.S. history. Welfare rolls have…

  6. Urticaria due to antihistamines

    National Research Council Canada - National Science Library

    Sánchez Morillas, L; Rojas Pérez-Ezquerra, P; Reaño Martos, M; Sanz, M L; Laguna Martínez, J J

    2011-01-01

    .... We report a patient with urticaria due to ingestion of ebastine and fexofenadine. Skin prick tests, patch tests, and basophil activation tests with the implicated drugs and antihistamines from other families were negative...

  7. Overcoming High Energy Backgrounds at Pulsed Spallation Sources

    CERN Document Server

    Cherkashyna, Nataliia; DiJulio, Douglas D.; Khaplanov, Anton; Pfeiffer, Dorothea; Scherzinger, Julius; Cooper-Jensen, Carsten P.; Fissum, Kevin G.; Ansell, Stuart; Iverson, Erik B.; Ehlers, Georg; Gallmeier, Franz X.; Panzner, Tobias; Rantsiou, Emmanouela; Kanaki, Kalliopi; Filges, Uwe; Kittelmann, Thomas; Extegarai, Maddi; Santoro, Valentina; Kirstein, Oliver; Bentley, Phillip M.

    2015-01-01

    Instrument backgrounds at neutron scattering facilities directly affect the quality and the efficiency of the scientific measurements that users perform. Part of the background at pulsed spallation neutron sources is caused by, and time-correlated with, the emission of high energy particles when the proton beam strikes the spallation target. This prompt pulse ultimately produces a signal, which can be highly problematic for a subset of instruments and measurements due to the time-correlated properties, and different to that from reactor sources. Measurements of this background have been made at both SNS (ORNL, Oak Ridge, TN, USA) and SINQ (PSI, Villigen, Switzerland). The background levels were generally found to be low compared to natural background. However, very low intensities of high-energy particles have been found to be detrimental to instrument performance in some conditions. Given that instrument performance is typically characterised by S/N, improvements in backgrounds can both improve instrument pe...

  8. 40 CFR 89.420 - Background sample.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Background sample. 89.420 Section 89... Procedures § 89.420 Background sample. (a) Background samples are produced by continuously drawing a sample... background samples may be produced and analyzed for each mode. Hence, a unique background value will be used...

  9. Binocular Coordination in Reading When Changing Background Brightness

    Directory of Open Access Journals (Sweden)

    Köpsel Anne

    2017-10-01

    Full Text Available Contradicting results concerning binocular coordination in reading have been reported: Liversedge et al. (2006 reported a dominance of uncrossed fixations, whereas Nuthmann and Kliegl (2009 observed more crossed fixations in reading. Based on both earlier and continuing studies, we conducted a reading experiment involving varying brightness of background and font. Calibration was performed using Gabor patches presented on grey background. During the experimental session, text had to be read either on dark, bright, or grey background. The data corroborates former results that showed a predominance of uncrossed fixations when reading on dark background, as well as those showing a predominance of crossed fixations, when reading on bright background. Besides these systematic shifts, the new results show an increase in unsystematic variability when changing the overall brightness from calibration to test. The origins of the effects need to be clarified in future research.

  10. Acid rain: a background report

    Energy Technology Data Exchange (ETDEWEB)

    Glustrom, L.; Stolzenberg, J.

    1982-07-08

    This Staff Brief was prepared for the Wisconsin Legislative Council's Special Committee on Acid Rain to provide an introduction to the issue of acid rain. It is divided into four parts. Part I provides an overview on the controversies surrounding the measurement, formation and effects of acid rain. As described in Part I, the term acid rain is used to describe the deposition of acidic components through both wet deposition (e.g., rain or snow) and dry deposition (e.g., direct contact between atmospheric constituents and the land, water or vegetation of the earth). Part II presents background information on state agency activities relating to acid rain in Wisconsin, describes what is known about the occurrence of, susceptibility to and effects of acid rain in Wisconsin, and provides information related to man-made sources of sulfur and nitrogen oxides in Wisconsin. Part III describes major policies and regulations relating to acid rain which have been or are being developed jointly by the United States and Canadian governments, by the United States government and by the State of Wisconsin. Part IV briefly discusses possible areas for Committee action.

  11. Plenoptic background oriented schlieren imaging

    Science.gov (United States)

    Klemkowsky, Jenna N.; Fahringer, Timothy W.; Clifford, Christopher J.; Bathel, Brett F.; Thurow, Brian S.

    2017-09-01

    The combination of the background oriented schlieren (BOS) technique with the unique imaging capabilities of a plenoptic camera, termed plenoptic BOS, is introduced as a new addition to the family of schlieren techniques. Compared to conventional single camera BOS, plenoptic BOS is capable of sampling multiple lines-of-sight simultaneously. Displacements from each line-of-sight are collectively used to build a four-dimensional displacement field, which is a vector function structured similarly to the original light field captured in a raw plenoptic image. The displacement field is used to render focused BOS images, which qualitatively are narrow depth of field slices of the density gradient field. Unlike focused schlieren methods that require manually changing the focal plane during data collection, plenoptic BOS synthetically changes the focal plane position during post-processing, such that all focal planes are captured in a single snapshot. Through two different experiments, this work demonstrates that plenoptic BOS is capable of isolating narrow depth of field features, qualitatively inferring depth, and quantitatively estimating the location of disturbances in 3D space. Such results motivate future work to transition this single-camera technique towards quantitative reconstructions of 3D density fields.

  12. APPENDICULAR INVAGINATION DUE TO ENDOMETRIOSIS

    Directory of Open Access Journals (Sweden)

    Vasja Kruh

    2003-12-01

    Full Text Available Background. Invagination of the vermiform appendix is a very rare occurrence. We summarize epidemiologic and etiologic factors, types of classification, symtomatology, diagnostic features and treatment.Patients and treatment. The authors present 49-years old female with long-standing abdominal pains, who came in our hospital due to acute exacerbation with sever abdominal pain. Because of progressive symptoms and sensitivity in the right-lower abdominal quadrant a diagnostic laparoscopy was performed. An anomaly of cecum and the absence of appendix vermiformis have forced us to proceed with laparotomy in McBurnay point. After cecotomy an invaginated gangrenous appendix was found. The histological examination revealed endometriosis.Conclusions. By presenting this extremely rare pathology we also want to emphasize the important role of diagnostic laparoscopy in front of acute abdomen.

  13. Screening Nonspecific Interactions of Peptides without Background Interference

    OpenAIRE

    Keefe, Andrew J.; Caldwell, Kyle; Nowinski, Ann K.; White, Andrew D.; Thakkar, Amit; Jiang, Shaoyi

    2012-01-01

    The need to discover new peptide sequences to perform particular tasks has lead to a variety of peptide screening methods: phage display, yeast display, bacterial display and resin display. These are effective screening methods because the role of background binding is often insignificant. In the field of nonfouling materials, however, a premium is placed on chemistries that have extremely low levels of nonspecific binding. Due to the presence of background binding, it is not possible to use ...

  14. Reducing 68Ge Background in Dark Matter Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kouzes, Richard T.; Orrell, John L.

    2011-03-01

    Experimental searches for dark matter include experiments with sub-0.5 keV-energy threshold high purity germanium detectors. Experimental efforts, in partnership with the CoGeNT Collaboration operating at the Soudan Underground Laboratory, are focusing on energy threshold reduction via noise abatement, reduction of backgrounds from cosmic ray generated isotopes, and ubiquitous environmental radioactive sources. The most significant cosmic ray produced radionuclide is 68Ge. This paper evaluates reducing this background by freshly mining and processing germanium ore. The most probable outcome is a reduction of the background by a factor of two, and at most a factor of four. A very cost effective alternative is to obtain processed Ge as soon as possible and store it underground for 18 months.

  15. Death due to asthma

    Directory of Open Access Journals (Sweden)

    Albert L. Sheffer

    1996-01-01

    Full Text Available The prevalence and fatality rate of asthma have increased worldwide. Underdiagnosis and undertreatment of asthma are central to the occurrence of fatal asthma. Atopy is the principal risk factor associated with asthma. However, consideration of the epidemiologic, physiologic, pharmacologic, pathologic and clinical parameters of asthma assessment may provide valuable insight into death due to asthma. Psychologic and socioeconomic factors may further aggravate the asthma status. Ethnic minorities are at increased risk of asthma. The perception of dyspnea may be blunted in asthma sufferers. Slow-onset fatal asthma may be associated with submucosal eosinophilic, whereas sudden-onset may be associated with submucosal neutrophilia. Fatal asthma occurs in patients abusing regular |32-agonist therapy. Peak flow assessment often provides insight into asthma deterioration prior to signs of respiratory distress. Markers of risk of death due to asthma further identify the fatality-prone asthma patient.

  16. Advanced Background Subtraction Applied to Aeroacoustic Wind Tunnel Testing

    Science.gov (United States)

    Bahr, Christopher J.; Horne, William C.

    2015-01-01

    An advanced form of background subtraction is presented and applied to aeroacoustic wind tunnel data. A variant of this method has seen use in other fields such as climatology and medical imaging. The technique, based on an eigenvalue decomposition of the background noise cross-spectral matrix, is robust against situations where isolated background auto-spectral levels are measured to be higher than levels of combined source and background signals. It also provides an alternate estimate of the cross-spectrum, which previously might have poor definition for low signal-to-noise ratio measurements. Simulated results indicate similar performance to conventional background subtraction when the subtracted spectra are weaker than the true contaminating background levels. Superior performance is observed when the subtracted spectra are stronger than the true contaminating background levels. Experimental results show limited success in recovering signal behavior for data where conventional background subtraction fails. They also demonstrate the new subtraction technique's ability to maintain a proper coherence relationship in the modified cross-spectral matrix. Beam-forming and de-convolution results indicate the method can successfully separate sources. Results also show a reduced need for the use of diagonal removal in phased array processing, at least for the limited data sets considered.

  17. Optimization of the Regularization in Background and Foreground Modeling

    Directory of Open Access Journals (Sweden)

    Si-Qi Wang

    2014-01-01

    Full Text Available Background and foreground modeling is a typical method in the application of computer vision. The current general “low-rank + sparse” model decomposes the frames from the video sequences into low-rank background and sparse foreground. But the sparse assumption in such a model may not conform with the reality, and the model cannot directly reflect the correlation between the background and foreground either. Thus, we present a novel model to solve this problem by decomposing the arranged data matrix D into low-rank background L and moving foreground M. Here, we only need to give the priori assumption of the background to be low-rank and let the foreground be separated from the background as much as possible. Based on this division, we use a pair of dual norms, nuclear norm and spectral norm, to regularize the foreground and background, respectively. Furthermore, we use a reweighted function instead of the normal norm so as to get a better and faster approximation model. Detailed explanation based on linear algebra about our two models will be presented in this paper. By the observation of the experimental results, we can see that our model can get better background modeling, and even simplified versions of our algorithms perform better than mainstream techniques IALM and GoDec.

  18. Death due to asthma

    OpenAIRE

    Sheffer, Albert L.

    1996-01-01

    The prevalence and fatality rate of asthma have increased worldwide. Underdiagnosis and undertreatment of asthma are central to the occurrence of fatal asthma. Atopy is the principal risk factor associated with asthma. However, consideration of the epidemiologic, physiologic, pharmacologic, pathologic and clinical parameters of asthma assessment may provide valuable insight into death due to asthma. Psychologic and socioeconomic factors may further aggravate the asthma status. Ethnic minoriti...

  19. Human due diligence.

    Science.gov (United States)

    Harding, David; Rouse, Ted

    2007-04-01

    Most companies do a thorough job of financial due diligence when they acquire other companies. But all too often, deal makers simply ignore or underestimate the significance of people issues in mergers and acquisitions. The consequences are severe. Most obviously, there's a high degree of talent loss after a deal's announcement. To make matters worse, differences in decision-making styles lead to infighting; integration stalls; and productivity declines. The good news is that human due diligence can help companies avoid these problems. Done early enough, it helps acquirers decide whether to embrace or kill a deal and determine the price they are willing to pay. It also lays the groundwork for smooth integration. When acquirers have done their homework, they can uncover capability gaps, points of friction, and differences in decision making. Even more important, they can make the critical "people" decisions-who stays, who goes, who runs the combined business, what to do with the rank and file-at the time the deal is announced or shortly thereafter. Making such decisions within the first 30 days is critical to the success of a deal. Hostile situations clearly make things more difficult, but companies can and must still do a certain amount of human due diligence to reduce the inevitable fallout from the acquisition process and smooth the integration. This article details the steps involved in conducting human due diligence. The approach is structured around answering five basic questions: Who is the cultural acquirer? What kind of organization do you want? Will the two cultures mesh? Who are the people you most want to retain? And how will rank-and-file employees react to the deal? Unless an acquiring company has answered these questions to its satisfaction, the acquisition it is making will be very likely to end badly.

  20. Preliminary background prediction for the INTEGRAL x-ray monitor

    DEFF Research Database (Denmark)

    Feroci, M.; Costa, E.; Budtz-Joergensen, C.

    1996-01-01

    a major role. Based on the information available at the present stage of the emission design, we have computed the instrumental background to be expected because of two main background components: direct diffuse x-ray background and secondary photons originated by the interactions of the primary cosmic......The JEM-X (joint European x-ray monitor) experiment will be flown onboard the ESA's INTEGRAL satellite. The instrumental background level of the two JEM-X twin detectors will depend on several parameters, among which the satellite orbit and mass distribution, and the detectors materials play...... rays with the spacecraft structures. This calculation has been carried out by means of a Monte Carlo simulation using the code MCNP. The background due to on- orbit material activation and to the primary cosmic rays direct interactions with the detecting medium has not been considered. The INTEGRAL...

  1. Cytology of Pericardial Effusion due to Malignancy

    Directory of Open Access Journals (Sweden)

    Kalogeraki Alexandra

    2016-09-01

    Full Text Available Background. Malignant pericardial effusion occurs in one tenth of all cancers. It is a very serious disorder that is mainly a secondary process due to metastasis because primary neoplasms of the pericardium such as mesotheliomas, sarcomas being exceedingly rare.

  2. Elevated Tank Due to Earthquake Even

    Directory of Open Access Journals (Sweden)

    Kotrasová Kamila

    2017-12-01

    Full Text Available Elevated reservoirs are mainly used for storing of variety water. During earthquake activity the fluid exerts impulsive and convective (sloshing effects on the walls and bottom of tank. This paper provides theoretical background for analytical calculating of elevated water tank due to earthquake even and deals with simplified seismic design procedures for elevated tanks.

  3. 40 CFR 90.422 - Background sample.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 20 2010-07-01 2010-07-01 false Background sample. 90.422 Section 90... Procedures § 90.422 Background sample. (a) Background samples are produced by drawing a sample of the dilution air during the exhaust collection phase of each test cycle mode. (1) An individual background...

  4. Associations between psychological variables and pain in experimental pain models. A systematic review

    DEFF Research Database (Denmark)

    Hansen, M S; Horjales-Araujo, E; Dahl, J B

    2015-01-01

    are predictive of the level of pain following experimental pain models. METHODS: A systematic search on the databases, PubMed, Embase, Cochcrane library, and Clinicaltrials.gov was performed during September 2014. All trials investigating the association between psychological variables and experimental pain...... and experimental pain. CONCLUSION: Psychological factors may have predictive value when investigating experimental pain. However, due to substantial heterogeneity and methodological shortcomings of the published literature, firm conclusions are not possible.......BACKGROUND: The association between pain and psychological characteristics has been widely debated. Thus, it remains unclear whether an individual's psychological profile influences a particular pain experience, or if previous pain experience contributes to a certain psychological profile...

  5. [Onychomycoses due to molds].

    Science.gov (United States)

    Chabasse, D; Pihet, M

    2014-12-01

    Onychomycoses represent about 30% of superficial mycosis that are encountered in Dermatology consults. Fungi such as dermatophytes, which are mainly found on the feet nails, cause nearly 50% of these onychopathies. Yeasts are predominantly present on hands, whereas non-dermatophytic moulds are very seldom involved in both foot and hand nails infections. According to literature, these moulds are responsible for 2 to 17% of onychomycoses. Nevertheless, we have to differentiate between onychomycoses due to pseudodermatophytes such as Neoscytalidium (ex-Scytalidium) and Onychocola canadensis, which present a high affinity for keratin, and onychomycoses due to filamentous fungi such as Aspergillus, Fusarium, Scopulariopsis, Acremonium... These saprophytic moulds are indeed most of the time considered as colonizers rather than real pathogens agents. Mycology and histopathology laboratories play an important role. They allow to identify the species that is involved in nail infection, but also to confirm parasitism by the fungus in the infected nails. Indeed, before attributing any pathogenic role to non-dermatophytic moulds, it is essential to precisely evaluate their pathogenicity through samples and accurate mycological and/or histological analysis. The treatment of onychomycoses due to non-dermatophytic moulds is difficult, as there is today no consensus. The choice of an antifungal agent will first depend on the species that is involved in the infection, but also on the severity of nail lesions and on the patient himself. In most cases, the onychomycosis will be cured with chemical or mechanical removing of the infected tissues, followed by a local antifungal treatment. In some cases, a systemic therapy will be discussed. Copyright © 2014 Elsevier Masson SAS. All rights reserved.

  6. A novel method to remove GPR background noise based on the similarity of non-neighboring regions

    Science.gov (United States)

    Montiel-Zafra, V.; Canadas-Quesada, F. J.; Vera-Candeas, P.; Ruiz-Reyes, N.; Rey, J.; Martinez, J.

    2017-09-01

    Ground penetrating radar (GPR) is a non-destructive technique that has been widely used in many areas of research, such as landmine detection or subsurface anomalies, where it is required to locate targets embedded within a background medium. One of the major challenges in the research of GPR data remains the improvement of the image quality of stone materials by means of detection of true anisotropies since most of the errors are caused by an incorrect interpretation by the users. However, it is complicated due to the interference of the horizontal background noise, e.g., the air-ground interface, that reduces the high-resolution quality of radargrams. Thus, weak or deep anisotropies are often masked by this type of noise. In order to remove the background noise obtained by GPR, this work proposes a novel background removal method assuming that the horizontal noise shows repetitive two-dimensional regions along the movement of the GPR antenna. Specifically, the proposed method, based on the non-local similarity of regions over the distance, computes similarities between different regions of the same depth in order to identify most repetitive regions using a criterion to avoid closer regions. Evaluations are performed using a set of synthetic and real GPR data. Experimental results show that the proposed method obtains promising results compared to the classic background removal techniques and the most recently published background removal methods.

  7. Speech recognition in natural background noise.

    Directory of Open Access Journals (Sweden)

    Julien Meyer

    Full Text Available In the real world, human speech recognition nearly always involves listening in background noise. The impact of such noise on speech signals and on intelligibility performance increases with the separation of the listener from the speaker. The present behavioral experiment provides an overview of the effects of such acoustic disturbances on speech perception in conditions approaching ecologically valid contexts. We analysed the intelligibility loss in spoken word lists with increasing listener-to-speaker distance in a typical low-level natural background noise. The noise was combined with the simple spherical amplitude attenuation due to distance, basically changing the signal-to-noise ratio (SNR. Therefore, our study draws attention to some of the most basic environmental constraints that have pervaded spoken communication throughout human history. We evaluated the ability of native French participants to recognize French monosyllabic words (spoken at 65.3 dB(A, reference at 1 meter at distances between 11 to 33 meters, which corresponded to the SNRs most revealing of the progressive effect of the selected natural noise (-8.8 dB to -18.4 dB. Our results showed that in such conditions, identity of vowels is mostly preserved, with the striking peculiarity of the absence of confusion in vowels. The results also confirmed the functional role of consonants during lexical identification. The extensive analysis of recognition scores, confusion patterns and associated acoustic cues revealed that sonorant, sibilant and burst properties were the most important parameters influencing phoneme recognition. . Altogether these analyses allowed us to extract a resistance scale from consonant recognition scores. We also identified specific perceptual consonant confusion groups depending of the place in the words (onset vs. coda. Finally our data suggested that listeners may access some acoustic cues of the CV transition, opening interesting perspectives for

  8. Credit where due.

    Science.gov (United States)

    Friedman, Steven G

    2016-08-01

    The history of medicine is filled with stories of tireless researchers who failed to get credit for their hard work. Examples of this include Rosalind Franklin, who helped to elucidate the structure of DNA; Frederick Banting, who helped to discover insulin; and Jay McLean, who discovered heparin. The founding of the field of vascular surgery provides one of the most vivid examples of uncredited work. Even though Alexis Carrel was an unpaid, untitled assistant in Charles Guthrie's laboratory, it was Carrel alone who received a Nobel Prize for their work. In an attempt to give credit where due, the reasons for this injustice are described. Copyright © 2016 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved.

  9. 32 CFR 761.2 - Background and general policy.

    Science.gov (United States)

    2010-07-01

    ... areas, due to their strategic nature or for purposes of defense, have been subjected to restrictions... 32 National Defense 5 2010-07-01 2010-07-01 false Background and general policy. 761.2 Section 761.2 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY ISLANDS UNDER NAVY...

  10. Fingerprints of Galactic Loop I on the Cosmic Microwave Background

    DEFF Research Database (Denmark)

    Liu, Hao; Mertsch, Philipp; Sarkar, Subir

    2014-01-01

    We investigate possible imprints of galactic foreground structures such as the "radio loops" in the derived maps of the cosmic microwave background. Surprisingly, there is evidence for these not only at radio frequencies through their synchrotron radiation, but also at microwave frequencies where...... due to primordial gravitational waves from inflation....

  11. Global Binary Continuity for Color Face Detection With Complex Background

    Science.gov (United States)

    Belavadi, Bhaskar; Mahendra Prashanth, K. V.; Joshi, Sujay S.; Suprathik, N.

    2017-08-01

    In this paper, we propose a method to detect human faces in color images, with complex background. The proposed algorithm makes use of basically two color space models, specifically HSV and YCgCr. The color segmented image is filled uniformly with a single color (binary) and then all unwanted discontinuous lines are removed to get the final image. Experimental results on Caltech database manifests that the purported model is able to accomplish far better segmentation for faces of varying orientations, skin color and background environment.

  12. [Keratitis due to Acanthamoeba].

    Science.gov (United States)

    Pérez-Irezábal, Julio; Martínez, Inés; Isasa, Patricia; Barrón, Jorge

    2006-10-01

    Free-living amebae appertaining to the genus Acanthamoeba, Naegleria and Balamuthia are the most prevalent protozoa found in the environment. These amebae have a cosmopolitan distribution in soil, air and water, providing multiple opportunities for contacts with humans and animals, although they only occasionally cause disease. Acanthamoeba spp. are the causative agent of granulomatous amebic encephalitis, a rare and often fatal disease of the central nervous system, and amebic keratitis, a painful disease of the eyes. Keratitis usually follows a chronic course due to the delay in diagnosis and subsequent treatment. The clear increase in Acanthamoeba keratitis in the last 20 years is related to the use and deficient maintenance of contact lenses, and to swimming while wearing them. The expected incidence is one case per 30,000 contact lens wearers per year, with 88% of cases occurring in persons wearing hydrogel lenses. This review presents information on the morphology, life-cycle and epidemiology of Acanthamoeba, as well as on diagnostic procedures (culture), appropriate antimicrobial therapy, and prevention measures.

  13. An experimental study to compare inflammatory response due to liquid or gas joint distension in horses submitted to arthroscopy Estudo experimental para comparar a resposta inflamatória decorrente da distensão líquida ou gasosa em cavalos submetidos à artroscopia

    Directory of Open Access Journals (Sweden)

    Renata Bello Rossetti

    2012-12-01

    Full Text Available PURPOSE: To assess comparatively the inflammatory response that follows CO2 or Ringer's lactate joint capsular distension of horses submitted to experimental arthroscopy METHODS: Each animal was submitted to a bilateral tarsocrural arthroscopy employing gas distention in one joint and fluid distention in the contralateral joint. Synovial fluid was evaluated at 0, six, 12, 24 and 48 hours post-operative. RESULTS: The use of CO2 for arthroscopy causes an acute and mild synovitis alike to the liquid capsular distension, showing similar synovial fluid increase of leukocytes, TP, and TNF-α. Although synovial fluid PGE2 content was higher in joints submitted to CO2 distension, lower levels of hemoglobin and leukocytes oxidative burst after surgery indicates that CO2 arthroscopy decreased intra-articular bleeding and activation of infiltrating leukocytes. CONCLUSIONS: The use of CO2 for arthroscopic examination causes acute and mild synovitis that is similar to the effects caused by the liquid capsular distension. CO2 also seems to decrease intra-articular bleeding and activation of leukocytes.OBJETIVO: Avaliar comparativamente a resposta inflamatória decorrente da distensão líquida ou gasosa em cavalos submetidos ao exame artroscópico. MÉTODOS: Cada animal foi submetido a uma artroscopia bilateral tarsocrural empregando uma distensão com gás em uma articulação e líquido na articulação contralateral. O líquido sinovial foi avaliado as zero, seis, 12, 24 e 48 horas do pós-operatório. RESULTADOS: A utilização de CO2 para a artroscopia provoca uma sinovite aguda e leve tal como a distensão capsular por líquido, mostrando um aumento similar de leucócitos, TP (proteína total e TNF-a. Embora no líquido sinovial a quantidade de PGE2 tenha sido maior nas articulações submetidas à distensão por CO2, níveis mais baixos de hemoglobina e explosão oxidativa de leucócitos após a cirurgia indica que a artroscopia com CO2 diminuiu o

  14. [National Elk Refuge background and operating statement

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a background on National Elk Refuge in Wyoming. Part I is solely background information concerning the physical characteristics, habitat, major...

  15. 16 CFR 1101.1 - General background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false General background. 1101.1 Section 1101.1 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS INFORMATION DISCLOSURE UNDER SECTION 6(b) OF THE CONSUMER PRODUCT SAFETY ACT Background § 1101.1 General background. (a...

  16. 45 CFR 650.16 - Background rights.

    Science.gov (United States)

    2010-10-01

    ... 45 Public Welfare 3 2010-10-01 2010-10-01 false Background rights. 650.16 Section 650.16 Public... Background rights. The Foundation will acquire rights to a research performer's pre-existing technology only... of the cognizant Program Manager, will negotiate a background rights provision. If the affected...

  17. Medication adherence in people of culturally and linguistically diverse backgrounds: a meta-analysis.

    Science.gov (United States)

    Manias, Elizabeth; Williams, Allison

    2010-06-01

    Medication adherence is of particular importance for people of culturally and linguistically diverse (CALD) backgrounds due to language difficulties, lack of social and organizational supports, lack of access to healthcare resources, and disengagement with the health-care system. To evaluate the impact of interventions to improve medication adherence in people of CALD backgrounds through a systematic review and meta-analysis. A search was performed using the following databases: Cochrane Database of Systematic Reviews, Cumulative Index to Nursing & Allied Health Literature, EMBASE, Journals@Ovid, PsychInfo, PubMed, Science Direct, Scopus, and Web of Science. Databases were searched from January 1978 to October 2009. Forty-six articles reviewed were assessed as being relevant, which included 36 randomized controlled trials, 2 observational cohort studies, and 8 quasi-experimental studies. The most common method for assessing medication adherence was self-reporting measures, such as the Morisky Scale and its modifications. Few studies used combinations of adherence measures, and adherence involving a medication event monitoring system (MEMS) was used in only 6 studies. Individuals of CALD backgrounds were recruited with people of non-CALD backgrounds and subsequent analyses tended to be undertaken of the whole sample. Twenty studies showed statistically significant improvements in medication adherence, 15 of which were randomized controlled trials. Six of the successful interventions involved delivery by a bilingual person or the use of translated materials and 4 involved the use of a conceptual model. Meta-analyses demonstrated modest improvements in medication adherence. Relatively little high-quality work has been conducted on adherence-enhancing interventions for people of CALD backgrounds. Greater attention needs to be given to examining the needs of specific CALD population groups. Future researchers should consider rigorously testing interventions that take

  18. Effects of placement point of background music on shopping website.

    Science.gov (United States)

    Lai, Chien-Jung; Chiang, Chia-Chi

    2012-01-01

    Consumer on-line behaviors are more important than ever due to highly growth of on-line shopping. The purposes of this study were to design placement methods of background music for shopping website and examine the effect on browsers' emotional and cognitive response. Three placement points of background music during the browsing, i.e. 2 min., 4 min., and 6 min. from the start of browsing were considered for entry points. Both browsing without music (no music) and browsing with constant music volume (full music) were treated as control groups. Participants' emotional state, approach-avoidance behavior intention, and action to adjust music volume were collected. Results showed that participants had a higher level of pleasure, arousal and approach behavior intention for the three placement points than for no music and full music. Most of the participants for full music (5/6) adjusted the background music. Only 16.7% (3/18) participants for other levels turn off the background music. The results indicate that playing background music after the start of browsing is benefit for on-line shopping atmosphere. It is inappropriate to place background music at the start of browsing shopping website. The marketer must manipulated placement methods of background music for a web store carefully.

  19. Optimal Background Estimators in Single-Molecule FRET Microscopy.

    Science.gov (United States)

    Preus, Søren; Hildebrandt, Lasse L; Birkedal, Victoria

    2016-09-20

    Single-molecule total internal reflection fluorescence (TIRF) microscopy constitutes an umbrella of powerful tools that facilitate direct observation of the biophysical properties, population heterogeneities, and interactions of single biomolecules without the need for ensemble synchronization. Due to the low signal/noise ratio in single-molecule TIRF microscopy experiments, it is important to determine the local background intensity, especially when the fluorescence intensity of the molecule is used quantitatively. Here we compare and evaluate the performance of different aperture-based background estimators used particularly in single-molecule Förster resonance energy transfer. We introduce the general concept of multiaperture signatures and use this technique to demonstrate how the choice of background can affect the measured fluorescence signal considerably. A new, to our knowledge, and simple background estimator is proposed, called the local statistical percentile (LSP). We show that the LSP background estimator performs as well as current background estimators at low molecular densities and significantly better in regions of high molecular densities. The LSP background estimator is thus suited for single-particle TIRF microscopy of dense biological samples in which the intensity itself is an observable of the technique. Copyright © 2016 Biophysical Society. Published by Elsevier Inc. All rights reserved.

  20. Background studies for the MINER Coherent Neutrino Scattering reactor experiment

    Energy Technology Data Exchange (ETDEWEB)

    Agnolet, G.; Baker, W. [Department of Physics and Astronomy, and the Mitchell Institute for Fundamental Physics and Astronomy, Texas A& M University, College Station, TX 77843 (United States); Barker, D. [School of Physics & Astronomy, University of Minnesota, Minneapolis, MN 55455 (United States); Beck, R. [Department of Physics and Astronomy, and the Mitchell Institute for Fundamental Physics and Astronomy, Texas A& M University, College Station, TX 77843 (United States); Carroll, T.J.; Cesar, J. [Department of Physics, University of Texas at Austin, Austin, TX 78712 (United States); Cushman, P. [School of Physics & Astronomy, University of Minnesota, Minneapolis, MN 55455 (United States); Dent, J.B. [Department of Physics, University of Louisiana at Lafayette, Lafayette, LA 70504 (United States); De Rijck, S. [Department of Physics, University of Texas at Austin, Austin, TX 78712 (United States); Dutta, B. [Department of Physics and Astronomy, and the Mitchell Institute for Fundamental Physics and Astronomy, Texas A& M University, College Station, TX 77843 (United States); Flanagan, W. [Department of Physics, University of Texas at Austin, Austin, TX 78712 (United States); Fritts, M. [School of Physics & Astronomy, University of Minnesota, Minneapolis, MN 55455 (United States); Gao, Y. [Department of Physics and Astronomy, and the Mitchell Institute for Fundamental Physics and Astronomy, Texas A& M University, College Station, TX 77843 (United States); Department of Physics & Astronomy, Wayne State University, Detroit 48201 (United States); Harris, H.R.; Hays, C.C. [Department of Physics and Astronomy, and the Mitchell Institute for Fundamental Physics and Astronomy, Texas A& M University, College Station, TX 77843 (United States); Iyer, V. [School of Physical Sciences, National Institute of Science Education and Research, Jatni - 752050 (India); and others

    2017-05-01

    The proposed Mitchell Institute Neutrino Experiment at Reactor (MINER) experiment at the Nuclear Science Center at Texas A&M University will search for coherent elastic neutrino-nucleus scattering within close proximity (about 2 m) of a 1 MW TRIGA nuclear reactor core using low threshold, cryogenic germanium and silicon detectors. Given the Standard Model cross section of the scattering process and the proposed experimental proximity to the reactor, as many as 5–20 events/kg/day are expected. We discuss the status of preliminary measurements to characterize the main backgrounds for the proposed experiment. Both in situ measurements at the experimental site and simulations using the MCNP and GEANT4 codes are described. A strategy for monitoring backgrounds during data taking is briefly discussed.

  1. Poisoning due to pyrethroids.

    Science.gov (United States)

    Bradberry, Sally M; Cage, Sarah A; Proudfoot, Alex T; Vale, J Allister

    2005-01-01

    current') ensues which, if it is sufficiently large and/or long, lowers the action potential threshold and causes repetitive firing; this may be the mechanism causing paraesthesiae. At high pyrethroid concentrations, the sodium tail current may be sufficiently great to prevent further action potential generation and 'conduction block' ensues. Only low pyrethroid concentrations are necessary to modify sensory neurone function. Type II pyrethroids also decrease chloride currents through voltage-dependent chloride channels and this action probably contributes the most to the features of poisoning with type II pyrethroids. At relatively high concentrations, pyrethroids can also act on GABA-gated chloride channels, which may be responsible for the seizures seen with severe type II poisoning. Despite their extensive world-wide use, there are relatively few reports of human pyrethroid poisoning. Less than ten deaths have been reported from ingestion or following occupational exposure. Occupationally, the main route of pyrethroid absorption is through the skin. Inhalation is much less important but increases when pyrethroids are used in confined spaces. The main adverse effect of dermal exposure is paraesthesiae, presumably due to hyperactivity of cutaneous sensory nerve fibres. The face is affected most commonly and the paraesthesiae are exacerbated by sensory stimulation such as heat, sunlight, scratching, sweating or the application of water. Pyrethroid ingestion gives rise within minutes to a sore throat, nausea, vomiting and abdominal pain. There may be mouth ulceration, increased secretions and/or dysphagia. Systemic effects occur 4-48 hours after exposure. Dizziness, headache and fatigue are common, and palpitations, chest tightness and blurred vision less frequent. Coma and convulsions are the principal life-threatening features. Most patients recover within 6 days, although there were seven fatalities among 573 cases in one series and one among 48 cases in another

  2. Study of the background in the measuring station at the n_TOF facility at CERN: sources and solutions

    CERN Document Server

    Zanini, L; Aerts, G; Andriamonje, Samuel A; Andrzejewski, J; Angelopoulous, A; Assimakopoulos, Panayiotis; Bacri, C-O; Badurek, G; Berthoumieux, E; Baumann, P; Beer, H; Benlliure, J; Berthier, B; Bondarenko, I; Borcea, C; Bos, A J J; Boscolo-Marchi, E; Bustreo, N; Calviño, F; Cano-Ott, D; Capote, R; Carlson, P; Charpak, Georges; Chauvin, N; Cennini, P; Chepel, V; Colonna, N; Cortés, G; Cortina-Gil, D; Corvi, F; Cusmano, A; Dababneh, S; Dahlfors, M; Damianoglou, D; David, S; Dimovasili, E; Domingo, C; Doroshenko, A; Duran-Escribano, I; Eleftheriadis, C; Embid, M; Ferrant, L; Ferrari, A; Ferreira-Marques, R; Frais-Kölbl, H; Furman, W; Fursov, B; Garzón, J A; Giomataris, Ioanis; Gledenov, Y; Gonzalez-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Gunsing, F; Haefner, P; Haight, R; Heil, M; Herrera-martinez, A; Hollander, P; Ioannou, P; Isaev, S; Jericha, E; Kadi, Y; Kappeler, F; Karadimos, D; Karamanis, D; Kayukova, A; Kazakov, L; Kelic, A; Ketlerov, V; Kitis, G; Köhler, P E; Kopach, Y; Kossionides, E; Kroshkina, I; Lacoste, V; Lamboudis, C; Leeb, H; Leprêtre, A; Lopes, M; Lozano, M; Marrone, S; Martínez-Val, J M; Mastinu, P; Mengoni, A; Meunier, R; Mezentsev, A J; Milazzo, P; Minguez, E; Mitrofanov, V; Moreau, C; Müller, A; Nicolis, N; Nikolenkov, V; Oberhummer, Heinz; Pakou, A; Pancin, J; Papadopoulous, K; Papaevangelou, T; Paradela, C; Paradelis, T; Pavlik, A; Pavlopoulos, P; Perrez-Parra, A; Perriale, L; Perlado, J M; Peskov, Vladimir; Piksaikin, V; Plag, R; Plompen, A; Plukis, A; Poch, A; Policarpo, Armando; Popov, A; Popov, Y P; Pretel, C; Quesada, J M; Radermacher, E; Rapp, W; Rauscher, T; Reifarth, R; Rejmund, F; Rubbia, Carlo; Rudolf, G; Rullhusen, P; Sakelliou, L; Saldaña, F; Samylin, B; Savvidis, I; Savvidis, S; Sedyshev, P; Stéphan, C; Szalanski, P; Tagliente, G; Taín, J L; Tapia, C; Tassan-Got, L; Terchychnyi, R; Tsabaris, C; Tsangas, N; van Eijk, C W E; Vannini, G; Ventura, A; Villamarin, A; Vlachoudis, V; Vlastou, R; Voinov, A; Voss, F; Wendler, H; Wiescher, M; Wisshak, K; Zanini, L; Zeinalov, S; Zhuravlev, B; CERN. Geneva. SPS and LHC Division

    2001-01-01

    A background roughly two orders of magnitude higher than tolerable was found in the n_TOF facility at CERN during the first measurements [1]. This note describes a series of additional measurements performed in the n_TOF experimental area to study the origin and the characteristics of the background. The program of these measurements was determined taking into account the results from the simulations carried out by the EET group [2]. A first phase of measurements confirmed what was expected from the simulations, namely that the dominant source of background was due to neutrons generated by negative muon capture. Actions to reduce the background were taken according to the results from both measurements and simulations. An iron shielding wall 3.2 m thick was then placed in between the sweeping magnet and the second collimator, with the purpose of stopping most of the muons. In a second phase of measurements, results showed that the additional shielding reduced the main component of the background by about a fa...

  3. Assessment of Radiation Background Variation for Moving Detection Systems

    Energy Technology Data Exchange (ETDEWEB)

    Miller, James Christopher [Los Alamos National Laboratory; Rennie, John Alan [Los Alamos National Laboratory; Toevs, James Waldo [Los Alamos National Laboratory; Wallace, Darrin J. [Los Alamos National Laboratory; Abhold, Mark Edward [Los Alamos National Laboratory

    2015-07-13

    The introduction points out that radiation backgrounds fluctuate across very short distances: factors include geology, soil composition, altitude, building structures, topography, and other manmade structures; and asphalt and concrete can vary significantly over short distances. Brief descriptions are given of the detection system, experimental setup, and background variation measurements. It is concluded that positive and negative gradients can greatly reduce the detection sensitivity of an MDS: negative gradients create opportunities for false negatives (nondetection), and positive gradients create a potentially unacceptable FAR (above 1%); the location of use for mobile detection is important to understand; spectroscopic systems provide more information for screening out false alarms and may be preferred for mobile use; and mobile monitor testing at LANL accounts for expected variations in the background.

  4. The Effect of Cultural Background Knowledge on Learning English Language

    Directory of Open Access Journals (Sweden)

    Dr. Ibrahim

    2013-12-01

    Full Text Available This study aims to investigate the effect of cultural background knowledge on learning English Language. It also aims to investigate if there are significant differences between subjects' performance in reading comprehension according to sex and general ability in English (GAE. The study aims at answering the following questions: 1 . To what extent is the effect of cultural background knowledge on subjects' performance in reading comprehension? 2 . What is the difference in performance in reading comprehension between male and female subjects who have cultural background knowledge and those who do not have any knowledge? 3. What is the differenc e between subjects' performance in reading comprehension texts which are loaded with American culture and their general ability in English. ? The population of th is study consisted of all first - year students majoring in English at Hebron University in th e first semester of the academic year 2011/2012. They were 600. The sample of the study consisted of 60 subjects, males and females divided into four groups, two experimental and two controlled. The researcher followed the experimental method. Means, stand ard deviations and Pearson Product Moment Correlation were calculated by using SPSS program. The study revealed the following results: 1. There are statistically significant differences in performance in reading comprehension between subjects who have cu ltural background knowledge and those who do not have any knowledge . 2 . There are no statistically significant differences in performance in reading comprehension between male and female subjects who have cultural background knowledge and those who do not have any knowledge. 3. Subjects' GAE revealed that there are significant differences in performance in reading comprehension between subjects who have cultural background knowledge and those who do not have any knowledge. In the light of the results of th e study, the researcher recommends the

  5. Physics of the Cosmic Microwave Background and the Planck Mission

    CERN Document Server

    Kurki-Suonio, Hannu

    2012-01-01

    This lecture is a sketch of the physics of the cosmic microwave background. The observed anisotropy can be divided into four main contributions: variations in the temperature and gravitational potential of the primordial plasma, Doppler effect from its motion, and a net red/blueshift the photons accumulate from traveling through evolving gravitational potentials on their way from the primordial plasma to here. These variations are due to primordial perturbations, probably caused by quantum fluctuations in the very early universe. The ongoing Planck satellite mission to observe the cosmic microwave background is also described.

  6. PENGARUH BACKGROUND MAHASISWA TERHADAP KINERJA AKADEMIK

    OpenAIRE

    Trianasari Angkawijaya; Yenny Sugiarti

    2014-01-01

    Abstract: The Effect of Students’ Background on Academic Performance. This study examines the effect of background variables on the academic performance of accounting students in a private university in Surabaya. The background variables under study included previous academic performance, prior knowledge on accounting, sex, motivation, preparedness, and expectations. The results show that previous academic performance, motivation, and expectations have positive and significant effects on the ...

  7. IRST infrared background analysis of bay environments

    CSIR Research Space (South Africa)

    Schwering, PBW

    2008-04-01

    Full Text Available environment. Some sensor management approaches for application in IRST systems is discussed. Keywords: Infrared backgrounds, coastal bay analysis, small surface target contrasts, IRST application. 1. INTRODUCTION More and more, coastal... in environments with highly cluttered backgrounds as well as rapidly varying atmospheric conditions. Threat contrasts may be low and varying in littoral environments, and the amount of background clutter can be severe. Electro-optical sensors, used for detection...

  8. Spotting neural spike patterns using an adversary background model.

    Science.gov (United States)

    Gat, I; Tishby, N

    2001-12-01

    The detection of a specific stochastic pattern embedded in an unknown background noise is a difficult pattern recognition problem, encountered in many applications such as word spotting in speech. A similar problem emerges when trying to detect a multineural spike pattern in a single electrical recording, embedded in the complex cortical activity of a behaving animal. Solving this problem is crucial for the identification of neuronal code words with specific meaning. The technical difficulty of this detection is due to the lack of a good statistical model for the background activity, which rapidly changes with the recording conditions and activity of the animal. This work introduces the use of an adversary background model. This model assumes that the background "knows" the pattern sought, up to a first-order statistics, and this "knowledge" creates a background composed of all the permutations of our pattern. We show that this background model is tightly connected to the type-based information-theoretic approach. Furthermore, we show that computing the likelihood ratio is actually decomposing the log-likelihood distribution according to types of the empirical counts. We demonstrate the application of this method for detection of the reward patterns in the basal ganglia of behaving monkeys, yielding some unexpected biological results.

  9. Technology Development for Cosmic Microwave Background Cosmology

    Science.gov (United States)

    Munson, Charles D.

    2017-05-01

    The Cosmic Microwave Background (CMB) offers a unique window into the early universe by probing thermal radiation remaining from the big bang. Due to its low temperature and bright foregrounds, its thorough characterization requires technological advancement beyond the current state-of-the-art. In this thesis, I present the development and fabrication of novel metamaterial silicon optics to improve the sensitivity of current and future CMB telescopes. By machining subwavelength features into the silicon surfaces, traditional antireflection coatings can be replaced by all-silicon metamaterials that significantly reduce reflections over previous approaches. I discuss the design of these structured surfaces and the design and construction of a sophisticated fabrication facility necessary to implement this technology on large diameter (30+ cm) lenses for the Atacama Cosmology Telescope Polarization project (ACTPol). I then apply this metamaterial technology to the development of improved free-space filters for millimeter and sub-millimeter wavelength imaging (focusing specifically on blocking infrared radiation, necessary for current cryogenic detector systems). This produces a highly effective infrared-blocking filter, blocking over 99% of the incident power from a 300 K blackbody while maintaining transmission of better than 99% in a target CMB observing band (between 70 and 170 GHz). I conclude with a discussion of the development of a real-space simulation framework to assist in better understanding current CMB results and forecasting for future experiments. By taking a CMB realization and adding to it accurate real-space modeling of the Sunyaev-Zel'dovich effect and weak lensing distortions (introduced by galaxy clusters), a better understanding of the impacts of large scale structure on the CMB can be obtained.

  10. Firearm Acquisition Without Background Checks: Results of a National Survey.

    Science.gov (United States)

    Miller, Matthew; Hepburn, Lisa; Azrael, Deborah

    2017-02-21

    In 1994, 40% of U.S. gun owners who had recently acquired a firearm did so without a background check. No contemporary estimates exist. To estimate the proportion of current U.S. gun owners who acquired their most recent firearm without a background check, by time since and manner of acquisition, for the nation as a whole and separately in states with and without legislation regulating private sales. Probability-based online survey. United States, 2015. 1613 adult gun owners. Current gun owners were asked where and when they acquired their last firearm; if they purchased the firearm; and whether, as part of that acquisition, they had a background check (or were asked to show a firearm license or permit). 22% (95% CI, 16% to 27%) of gun owners who reported obtaining their most recent firearm within the previous 2 years reported doing so without a background check. For firearms purchased privately within the previous 2 years (that is, other than from a store or pawnshop, including sales between individuals in person, online, or at gun shows), 50% (CI, 35% to 65%) were obtained without a background check. This percentage was 26% (CI, 5% to 47%) for owners residing in states regulating private firearm sales and 57% (CI, 40% to 75%) for those living in states without regulations on private firearm sales. Potential inaccuracies due to recall and social desirability bias. 22% of current U.S. gun owners who acquired a firearm within the past 2 years did so without a background check. Although this represents a smaller proportion of gun owners obtaining firearms without background checks than in the past, millions of U.S. adults continue to acquire guns without background checks, especially in states that do not regulate private firearm sales. Fund for a Safer Future and the Joyce Foundation.

  11. Hanford Site background: Part 1, Soil background for nonradioactive analytes. Revision 1, Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    Volume two contains the following appendices: Description of soil sampling sites; sampling narrative; raw data soil background; background data analysis; sitewide background soil sampling plan; and use of soil background data for the detection of contamination at waste management unit on the Hanford Site.

  12. 12 CFR 609.905 - Background.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Background. 609.905 Section 609.905 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ELECTRONIC COMMERCE General Rules § 609.905 Background. The Farm Credit Administration (FCA) wants to create a flexible regulatory environment that facilitates electronic commerce (E-commerce) and...

  13. Statistically tuned Gaussian background subtraction technique for ...

    Indian Academy of Sciences (India)

    Sample videos of various properties such as cluttered background, small objects, moving background and multiple objects are considered for evaluation. The technique is statistically compared with frame differencing technique, temporal median method and mixture of Gaussian model and performance evaluation is done to ...

  14. 16 CFR 1406.2 - Background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Background. 1406.2 Section 1406.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS COAL AND WOOD BURNING APPLIANCES-NOTIFICATION OF PERFORMANCE AND TECHNICAL DATA § 1406.2 Background. (a) Fire data analyzed by the...

  15. 10 CFR 1022.1 - Background.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Background. 1022.1 Section 1022.1 Energy DEPARTMENT OF ENERGY (GENERAL PROVISIONS) COMPLIANCE WITH FLOODPLAIN AND WETLAND ENVIRONMENTAL REVIEW REQUIREMENTS General § 1022.1 Background. (a) Executive Order (E.O.) 11988—Floodplain Management (May 24, 1977) directs...

  16. 40 CFR 761.380 - Background.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Background. 761.380 Section 761.380 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT....380 Background. This subpart provides self-implementing criteria for validating the conditions for use...

  17. 7 CFR 799.1 - Background.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Background. 799.1 Section 799.1 Agriculture Regulations of the Department of Agriculture (Continued) FARM SERVICE AGENCY, DEPARTMENT OF AGRICULTURE... ENVIRONMENTAL POLICY ACT § 799.1 Background. The National Environmental Policy Act (NEPA) of 1969 (42 U.S.C...

  18. 16 CFR 1031.2 - Background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Background. 1031.2 Section 1031.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION EMPLOYEE INVOLVEMENT IN VOLUNTARY STANDARDS ACTIVITIES General Policies § 1031.2 Background. (a) Congress enacted the...

  19. 44 CFR 350.3 - Background.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Background. 350.3 Section 350.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND... § 350.3 Background. (a) On December 7, 1979, the President directed the Administrator of FEMA to take...

  20. 32 CFR 701.56 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 701.56 Section 701.56 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... DOCUMENTS AFFECTING THE PUBLIC FOIA Exemptions § 701.56 Background. The FOIA is a disclosure statute whose...

  1. 41 CFR 128-1.8001 - Background.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Background. 128-1.8001 Section 128-1.8001 Public Contracts and Property Management Federal Property Management Regulations System (Continued) DEPARTMENT OF JUSTICE 1-INTRODUCTION 1.80-Seismic Safety Program § 128-1.8001 Background. The...

  2. 32 CFR 763.3 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 763.3 Section 763.3 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY ISLANDS UNDER NAVY JURISDICTION RULES GOVERNING PUBLIC ACCESS Entry Regulations for Kaho'olawe Island, Hawaii § 763.3 Background. (a) Kaho'olawe Island...

  3. 32 CFR 701.40 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 701.40 Section 701.40 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY UNITED STATES NAVY REGULATIONS AND... DOCUMENTS AFFECTING THE PUBLIC FOIA Fees § 701.40 Background. (a) The DON follows the uniform fee schedule...

  4. 16 CFR 1404.2 - Background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Background. 1404.2 Section 1404.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS CELLULOSE INSULATION § 1404.2 Background. Based on available fire incident information, engineering analysis of the probable...

  5. 22 CFR 1501.2 - Background.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 2 2010-04-01 2010-04-01 true Background. 1501.2 Section 1501.2 Foreign Relations AFRICAN DEVELOPMENT FOUNDATION ORGANIZATION Substantive Rule of General Applicability § 1501.2 Background. (a) The African Development Foundation (“ADF”) is a wholly-owned corporation of the United States...

  6. 14 CFR 1217.102 - Background.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Background. 1217.102 Section 1217.102 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION DUTY-FREE ENTRY OF SPACE ARTICLES § 1217.102 Background. In order to encourage and facilitate the use of NASA's launch services for the...

  7. 18 CFR 707.1 - Background.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Background. 707.1 Section 707.1 Conservation of Power and Water Resources WATER RESOURCES COUNCIL COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT (NEPA) General § 707.1 Background. (a) The National Environmental Policy...

  8. 33 CFR 236.4 - Background.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Background. 236.4 Section 236.4 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE WATER... QUALITY § 236.4 Background. (a) The role of the Corps of Engineers in the development of water and related...

  9. 7 CFR 1720.2 - Background.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Background. 1720.2 Section 1720.2 Agriculture Regulations of the Department of Agriculture (Continued) RURAL UTILITIES SERVICE, DEPARTMENT OF AGRICULTURE GUARANTEES FOR BONDS AND NOTES ISSUED FOR ELECTRIFICATION OR TELEPHONE PURPOSES § 1720.2 Background. The...

  10. 40 CFR 761.360 - Background.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Background. 761.360 Section 761.360 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... Wash/Rinse Method for Decontaminating Non-Porous Surfaces § 761.360 Background. The double wash/rinse...

  11. 20 CFR 410.700 - Background.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false Background. 410.700 Section 410.700 Employees' Benefits SOCIAL SECURITY ADMINISTRATION FEDERAL COAL MINE HEALTH AND SAFETY ACT OF 1969, TITLE IV-BLACK... Reform Act (BLBRA) of 1977 § 410.700 Background. (a) The Black Lung Benefits Reform Act of 1977 broadens...

  12. 32 CFR 770.42 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 770.42 Section 770.42 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES RULES LIMITING PUBLIC..., Connecticut § 770.42 Background. Naval Submarine Base New London maintains and operates facilities to support...

  13. Nonrelativistic superparticle in a curved background

    NARCIS (Netherlands)

    Bergshoeff, Eric; Gomis, Joaquim; Kovacevic, Marija; Parra, Lorena; Rosseel, Jan; Zojer, Thomas

    2014-01-01

    Using a component formulation, we construct the supersymmetric action for a superparticle in a three-dimensional Newton-Cartan supergravity background and clarify its symmetries. Our construction proceeds by first constructing the superparticle in a flat background. Next, by boosting up the

  14. 47 CFR 201.0 - Background.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Background. 201.0 Section 201.0 Telecommunication OFFICE OF SCIENCE AND TECHNOLOGY POLICY AND NATIONAL SECURITY COUNCIL EXECUTIVE POLICY § 201.0 Background. National policy with respect to the conservation, allocation and use of the Nation's...

  15. 44 CFR 334.3 - Background.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Background. 334.3 Section 334.3 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF HOMELAND SECURITY PREPAREDNESS GRADUATED MOBILIZATION RESPONSE § 334.3 Background. (a) The GMR system is designed to...

  16. 32 CFR 770.49 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 770.49 Section 770.49 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES RULES LIMITING PUBLIC..., Washington § 770.49 Background. (a) Puget Sound Naval Shipyard is a major naval ship repair facility, with...

  17. 32 CFR 770.37 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 770.37 Section 770.37 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES RULES LIMITING PUBLIC... § 770.37 Background. In accordance with 32 CFR 765.4, Naval installations and properties in Puerto Rico...

  18. 14 CFR 1214.302 - Background.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 5 2010-01-01 2010-01-01 false Background. 1214.302 Section 1214.302 Aeronautics and Space NATIONAL AERONAUTICS AND SPACE ADMINISTRATION SPACE FLIGHT Payload Specialists for Space Transportation System (STS) Missions § 1214.302 Background. (a) The Space Transportation System (STS) has been...

  19. 32 CFR 770.54 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 770.54 Section 770.54 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES RULES LIMITING PUBLIC... Hampshire § 770.54 Background. (a) Portsmouth Naval Shipyard maintains and operates facilities “to provide...

  20. 32 CFR 1290.5 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Background. 1290.5 Section 1290.5 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS PREPARING... Background. (a) DoD Instruction 6055.4 requires that all traffic violations occurring on DoD installations be...

  1. 2 CFR 225.15 - Background.

    Science.gov (United States)

    2010-01-01

    ... 2 Grants and Agreements 1 2010-01-01 2010-01-01 false Background. 225.15 Section 225.15 Grants and Agreements OFFICE OF MANAGEMENT AND BUDGET CIRCULARS AND GUIDANCE Reserved COST PRINCIPLES FOR STATE, LOCAL, AND INDIAN TRIBAL GOVERNMENTS (OMB CIRCULAR A-87) § 225.15 Background. As part of the government-wide...

  2. 32 CFR 1292.3 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 6 2010-07-01 2010-07-01 false Background. 1292.3 Section 1292.3 National Defense Other Regulations Relating to National Defense DEFENSE LOGISTICS AGENCY MISCELLANEOUS SECURITY OF DLA ACTIVITIES AND RESOURCES § 1292.3 Background. Section 21 of the Internal Security Act of 1950...

  3. 28 CFR 61.1 - Background.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 2 2010-07-01 2010-07-01 false Background. 61.1 Section 61.1 Judicial Administration DEPARTMENT OF JUSTICE (CONTINUED) PROCEDURES FOR IMPLEMENTING THE NATIONAL ENVIRONMENTAL POLICY ACT General § 61.1 Background. (a) The National Environmental Policy Act of 1969 (NEPA), 42 U.S.C...

  4. 40 CFR 11.2 - Background.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Background. 11.2 Section 11.2 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY GENERAL SECURITY CLASSIFICATION REGULATIONS PURSUANT TO EXECUTIVE ORDER 11652 § 11.2 Background. While the Environmental Protection Agency does not...

  5. 36 CFR 401.3 - Background.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false Background. 401.3 Section 401.3 Parks, Forests, and Public Property AMERICAN BATTLE MONUMENTS COMMISSION MONUMENTS AND MEMORIALS § 401.3 Background. Following World War I many American individuals, organizations and governmental...

  6. 48 CFR 1523.7000 - Background.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Background. 1523.7000 Section 1523.7000 Federal Acquisition Regulations System ENVIRONMENTAL PROTECTION AGENCY SOCIOECONOMIC... Computer Equipment 1523.7000 Background. (a) Executive Order 12845 requires the Federal Government to...

  7. 32 CFR 3.2 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 1 2010-07-01 2010-07-01 false Background. 3.2 Section 3.2 National Defense Department of Defense OFFICE OF THE SECRETARY OF DEFENSE ACQUISITION TRANSACTIONS OTHER THAN CONTRACTS, GRANTS, OR COOPERATIVE AGREEMENTS FOR PROTOTYPE PROJECTS § 3.2 Background. “Other transactions” is the...

  8. 16 CFR 1402.2 - Background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Background. 1402.2 Section 1402.2 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION CONSUMER PRODUCT SAFETY ACT REGULATIONS CB BASE STATION ANTENNAS, TV ANTENNAS, AND SUPPORTING STRUCTURES § 1402.2 Background. As a result of numerous...

  9. 32 CFR 732.1 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 732.1 Section 732.1 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY PERSONNEL NONNAVAL MEDICAL AND DENTAL CARE General § 732.1 Background. When a U.S. Navy or Marine Corps member or a Canadian Navy or Marine Corps member...

  10. 12 CFR 408.1 - Background.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 4 2010-01-01 2010-01-01 false Background. 408.1 Section 408.1 Banks and Banking EXPORT-IMPORT BANK OF THE UNITED STATES PROCEDURES FOR COMPLIANCE WITH THE NATIONAL ENVIRONMENTAL POLICY ACT General § 408.1 Background. (a) The National Environmental Policy Act (NEPA) of 1969 (42 U.S.C...

  11. 32 CFR 770.17 - Background.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 5 2010-07-01 2010-07-01 false Background. 770.17 Section 770.17 National Defense Department of Defense (Continued) DEPARTMENT OF THE NAVY MISCELLANEOUS RULES RULES LIMITING PUBLIC..., Washington § 770.17 Background. (a) SUBASE Bangor has been designated as the West Coast home port of the...

  12. 42 CFR 81.0 - Background.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Background. 81.0 Section 81.0 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES OCCUPATIONAL SAFETY AND HEALTH RESEARCH AND... OCCUPATIONAL ILLNESS COMPENSATION PROGRAM ACT OF 2000 Introduction § 81.0 Background. The Energy Employees...

  13. Multiple Scatters in Single Site Gamma Backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Brodsky, J. P. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-09-16

    nEXO aims to reduce its gamma backgrounds by taking advantage of the fact that a large number of gammas that would otherwise be backgrounds will undergo multiple compton scattering in the TPC and produce spatially distinct signals. These multi-sited (MS) events can be excluded from the 0νββ search.

  14. 28 CFR 23.2 - Background.

    Science.gov (United States)

    2010-07-01

    ... 28 Judicial Administration 1 2010-07-01 2010-07-01 false Background. 23.2 Section 23.2 Judicial Administration DEPARTMENT OF JUSTICE CRIMINAL INTELLIGENCE SYSTEMS OPERATING POLICIES § 23.2 Background. It is recognized that certain criminal activities including but not limited to loan sharking, drug trafficking, trafficking in stolen property,...

  15. Experimental Search for Pentaquarks

    CERN Document Server

    Hicks, K

    2005-01-01

    The experimental evidence for pentaquarks, both old an new, is discussed. Constraints due to $K^+N$ scattering data from previous decades is first reviewed, followed by experiments with positive evidence and those with null results. Finally, the problem of the narrow width of the Theta+ pentaquark is discussed, along with theoretical implications.

  16. Gravitational anomalies on the Newton-Cartan background

    Science.gov (United States)

    Fernandes, Karan; Mitra, Arpita

    2017-10-01

    We derive the trace and diffeomorphism anomalies of the Schrödinger field minimally coupled to the Newton-Cartan background using Fujikawa's path integral approach. This approach, in particular, enables us to calculate the one-loop contributions due to all the fields of the Newton-Cartan structure. We determine the coefficients and demonstrate that gravitational anomalies for this theory always arise in odd dimensions. Because of the gauge field contribution of the background, we find that in 2 +1 dimensions, the trace anomaly contains terms which have a form similar to that of the 1 +1 and 3 +1 dimensional relativistic trace anomalies. The term similar to the 1 +1 dimensional relativistic trace anomaly provides a type A contribution on Newton-Cartan backgrounds which satisfy the Frobenius condition, in contrast with the result of Lifshitz spacetimes. As an application, we demonstrate that the coefficient of this term satisfies a c-theorem condition.

  17. Beam-gas Background Observations at LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00214737; The ATLAS collaboration; Alici, Andrea; Lazic, Dragoslav-Laza; Alemany Fernandez, Reyes; Alessio, Federico; Bregliozzi, Giuseppe; Burkhardt, Helmut; Corti, Gloria; Guthoff, Moritz; Manousos, Athanasios; Sjoebaek, Kyrre; D'Auria, Saverio

    2017-01-01

    Observations of beam-induced background at LHC during 2015 and 2016 are presented in this paper. The four LHC experiments use the non-colliding bunches present in the physics-filling pattern of the accelerator to trigger on beam-gas interactions. During luminosity production the LHC experiments record the beam-gas interactions using dedicated background monitors. These data are sent to the LHC control system and are used to monitor the background levels at the experiments during accelerator operation. This is a very important measurement, since poor beam-induced background conditions can seriously affect the performance of the detectors. A summary of the evolution of the background levels during 2015 and 2016 is given in these proceedings.

  18. PENGARUH BACKGROUND MAHASISWA TERHADAP KINERJA AKADEMIK

    Directory of Open Access Journals (Sweden)

    Trianasari Angkawijaya

    2014-09-01

    Full Text Available Abstract: The Effect of Students’ Background on Academic Performance. This study examines the effect of background variables on the academic performance of accounting students in a private university in Surabaya. The background variables under study included previous academic performance, prior knowledge on accounting, sex, motivation, preparedness, and expectations. The results show that previous academic performance, motivation, and expectations have positive and significant effects on the students’ overall academic performance in accounting, while preparedness affects only the students’ performance in management accounting. In contrast, prior knowledge on accounting and sex do not give significant impacts to the students’ overall academic performance.These findings indicate the importance of previous aca­demic performance as well as motivation and expectations as background variables in current academic performance. Keywords: students’ background, academic performance, accounting Abstrak: Pengaruh Background Mahasiswa terhadap Kinerja Akademik. Penelitian ini mengkaji pengaruh variabel background terhadap kinerja akademik mahasiswa akuntansi di Universitas Surabaya. Lima variabel background utama dipergunakan, yaitu kinerja akademik sebelumnya, pengetahuan akun­tansi sebelumnya, jenis kelamin, motivasi, kesiapan, dan ekspektasi. Hipotesis diuji menggunakan model regresi linier berganda OLS dan Robust Standar Error. Hasil penelitian memerlihatkan bahwa kinerja akademik sebelumnya, motivasi, dan ekspektasi memiliki pengaruh positif signifikan terhadap kinerja akademik keseluruhan, sementara kesiapan memberikan pengaruh positif hanya pada kinerja akademik akuntansi manajemen. Sebaliknya, pengetahuan akuntansi sebelumnya dan jenis kelamin tidak memberi­kan pengaruh signifikan terhadap kinerja akademik keseluruhan. Temuan ini mengindikasikan bahwa kinerja akademik sebelumnya beserta motivasi dan ekspektasi adalah variabel background

  19. Trichloromethyl compounds - natural background concentrations and fates within and

    DEFF Research Database (Denmark)

    Albers, Christian Nyrop; Hansen, Poul Erik; Jacobsen, Ole Stig

    2010-01-01

    Pollution with organochlorines has received major attention due to various environmental effects, but it is now increasingly recognized, that they also take part in biogeochemical cycles and that natural background concentrations exist for several chlorinated compounds. We here report the natural....... Other positive relations occur, which in combination with chlorination experiments performed in the laboratory, point to the fact that all the trichloromethyl compounds may be formed concurrently in the soil, and their subsequent fates then differ due to different physical, chemical and biological...

  20. [Sadomasochism and dreams in the background of Kafka's poetry].

    Science.gov (United States)

    Leonhard, K

    1986-06-01

    Kafka's detailed descriptions of individuals being physically and psychically tortured can only be understood when accepting a sado-masochistic background. On the other hand, the discrepancies and absurdities, appearing again and again in his poetic products, are due to his habit of taking dream and its illogical connections as a model. The specific feature of dream with its central and peripheral phenomena is often identifiable in Kafka's descriptions. Whether he intended to present symbols is uncertain.

  1. String pair production in non homogeneous backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Bolognesi, S. [Department of Physics “E. Fermi” University of Pisa, and INFN - Sezione di Pisa,Largo Pontecorvo, 3, Ed. C, 56127 Pisa (Italy); Rabinovici, E. [Racah Institute of Physics, The Hebrew University of Jerusalem,91904 Jerusalem (Israel); Tallarita, G. [Departamento de Ciencias, Facultad de Artes Liberales,Universidad Adolfo Ibáñez, Santiago 7941169 (Chile)

    2016-04-28

    We consider string pair production in non homogeneous electric backgrounds. We study several particular configurations which can be addressed with the Euclidean world-sheet instanton technique, the analogue of the world-line instanton for particles. In the first case the string is suspended between two D-branes in flat space-time, in the second case the string lives in AdS and terminates on one D-brane (this realizes the holographic Schwinger effect). In some regions of parameter space the result is well approximated by the known analytical formulas, either the particle pair production in non-homogeneous background or the string pair production in homogeneous background. In other cases we see effects which are intrinsically stringy and related to the non-homogeneity of the background. The pair production is enhanced already for particles in time dependent electric field backgrounds. The string nature enhances this even further. For spacial varying electrical background fields the string pair production is less suppressed than the rate of particle pair production. We discuss in some detail how the critical field is affected by the non-homogeneity, for both time and space dependent electric field backgrouds. We also comment on what could be an interesting new prediction for the small field limit. The third case we consider is pair production in holographic confining backgrounds with homogeneous and non-homogeneous fields.

  2. Sources of the Radio Background Considered

    Energy Technology Data Exchange (ETDEWEB)

    Singal, J.; /KIPAC, Menlo Park /Stanford U.; Stawarz, L.; /KIPAC, Menlo Park /Stanford U. /Jagiellonian U., Astron. Observ.; Lawrence, A.; /Edinburgh U., Inst. Astron. /KIPAC, Menlo Park /Stanford U.; Petrosian, V.; /KIPAC, Menlo Park /Stanford U., Phys. Dept. /Stanford U., Appl. Phys. Dept.

    2011-08-22

    We investigate possible origins of the extragalactic radio background reported by the ARCADE 2 collaboration. The surface brightness of the background is several times higher than that which would result from currently observed radio sources. We consider contributions to the background from diffuse synchrotron emission from clusters and the intergalactic medium, previously unrecognized flux from low surface brightness regions of radio sources, and faint point sources below the flux limit of existing surveys. By examining radio source counts available in the literature, we conclude that most of the radio background is produced by radio point sources that dominate at sub {mu}Jy fluxes. We show that a truly diffuse background produced by elections far from galaxies is ruled out because such energetic electrons would overproduce the observed X-ray/{gamma}-ray background through inverse Compton scattering of the other photon fields. Unrecognized flux from low surface brightness regions of extended radio sources, or moderate flux sources missed entirely by radio source count surveys, cannot explain the bulk of the observed background, but may contribute as much as 10%. We consider both radio supernovae and radio quiet quasars as candidate sources for the background, and show that both fail to produce it at the observed level because of insufficient number of objects and total flux, although radio quiet quasars contribute at the level of at least a few percent. We conclude that the most important population for production of the background is likely ordinary starforming galaxies above redshift 1 characterized by an evolving radio far-infrared correlation, which increases toward the radio loud with redshift.

  3. Do instantons like a colorful background?

    Energy Technology Data Exchange (ETDEWEB)

    Gies, H.; Pawlowski, J.M.; Wetterich, C. [Heidelberg Univ. (Germany). Inst. fuer Theoretische Physik; Jaeckel, J. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany)

    2006-08-15

    We investigate chiral symmetry breaking and color symmetry breaking in QCD. The effective potential of the corresponding scalar condensates is discussed in the presence of non-perturbative contributions from the semiclassical one-instanton sector. We concentrate on a color singlet scalar background which can describe chiral condensation, as well as a color cotet scalar background which can generate mass for the gluons. Whereas a non-vanishing singlet chiral field is favored by the instantons, we have found no indication for a preference of color octet backgrounds. (orig.)

  4. Background Suppression Effects on Signal Estimation

    Energy Technology Data Exchange (ETDEWEB)

    Burr, Tom [Los Alamos National Laboratory

    2008-01-01

    Gamma detectors at border crossings are intended to detect illicit nuclear material. One performance challenge involves the fact that vehicles suppress the natural background, thus potentially reducing detection probability for threat items. Methods to adjust for background suppression have been considered in related but different settings. Here, methods to adjust for background suppression are tested in the context of signal estimation. Adjustment methods include several clustering options. We find that for the small-to-moderate suppression magnitudes exhibited in the analyzed data, suppression adjustment is only moderatel helpful in locating the signal peak, and in estimating its width or magnitude.

  5. Background music: effects on attention performance.

    Science.gov (United States)

    Shih, Yi-Nuo; Huang, Rong-Hwa; Chiang, Hsin-Yu

    2012-01-01

    Previous studies indicate that noise may affect worker attention. However, some background music in the work environment can increase worker satisfaction and productivity. This study compared how music with, and without, lyrics affects human attention. One hundred and two participants, aged 20-24 years, were recruited into this study. Fifty-six males and 46 females participated in this study. Background music with, and without lyrics, was tested for effects on listener concentration in attention testing using a randomized controlled trial (RCT) study. The comparison results revealed that background music with lyrics had significant negative effects on concentration and attention. The findings suggest that, if background music is played in the work environment, music without lyrics is preferable because songs with lyrics are likely to reduce worker attention and performance.

  6. History and background of the project

    Digital Repository Service at National Institute of Oceanography (India)

    Jauhari, P.; Nair, R.R.

    The history of oceanography, the discovery of manganese nodules and the background of the developments in nodule research and mining is given The first nodules were collected in 1981 on board the research vessel R V Gaveshani Following the success...

  7. The Spin-2 Equation on Minkowski Background

    CERN Document Server

    Beyer, Florian; Frauendiener, Jörg; Whale, Ben

    2014-01-01

    The linearised general conformal field equations in their first and second order form are used to study the behaviour of the spin-2 zero-rest-mass equation on Minkowski background in the vicinity of space-like infinity.

  8. Comparative study of background subtraction algorithms

    Science.gov (United States)

    Benezeth, Yannick; Jodoin, Pierre-Marc; Emile, Bruno; Laurent, Hélène; Rosenberger, Christophe

    2010-07-01

    We present a comparative study of several state-of-the-art background subtraction methods. Approaches ranging from simple background subtraction with global thresholding to more sophisticated statistical methods have been implemented and tested on different videos with ground truth. The goal is to provide a solid analytic ground to underscore the strengths and weaknesses of the most widely implemented motion detection methods. The methods are compared based on their robustness to different types of video, their memory requirements, and the computational effort they require. The impact of a Markovian prior as well as some postprocessing operators are also evaluated. Most of the videos used come from state-of-the-art benchmark databases and represent different challenges such as poor SNR, multimodal background motion, and camera jitter. Overall, we not only help to better understand for which type of videos each method best suits but also estimate how, sophisticated methods are better compared to basic background subtraction methods.

  9. Quantitative Pathology: Historical Background, Clinical Research ...

    African Journals Online (AJOL)

    Quantitative Pathology: Historical Background, Clinical Research and Application of Nuclear Morphometry and DNA Image Cytometry. A Buhmeida. Abstract. No Abstract Keywords: quantitative, pathology, nuclear, morphometry, cytometry, histogram. Libyan Journal of Medicine Vol. 1 (2) 2006: pp. 126-139.

  10. Standard Model Background of the Cosmological Collider.

    Science.gov (United States)

    Chen, Xingang; Wang, Yi; Xianyu, Zhong-Zhi

    2017-06-30

    The inflationary universe can be viewed as a "cosmological collider" with an energy of the Hubble scale, producing very massive particles and recording their characteristic signals in primordial non-Gaussianities. To utilize this collider to explore any new physics at very high scales, it is a prerequisite to understand the background signals from the particle physics standard model. In this Letter we describe the standard model background of the cosmological collider.

  11. Mathematical Background of Public Key Cryptography

    DEFF Research Database (Denmark)

    Frey, Gerhard; Lange, Tanja

    2005-01-01

    The two main systems used for public key cryptography are RSA and protocols based on the discrete logarithm problem in some cyclic group. We focus on the latter problem and state cryptographic protocols and mathematical background material.......The two main systems used for public key cryptography are RSA and protocols based on the discrete logarithm problem in some cyclic group. We focus on the latter problem and state cryptographic protocols and mathematical background material....

  12. BKGE: Fermi-LAT Background Estimator

    Science.gov (United States)

    Vasileiou, Vlasios

    2014-11-01

    The Fermi-LAT Background Estimator (BKGE) is a publicly available open-source tool that can estimate the expected background of the Fermi-LAT for any observational conguration and duration. It produces results in the form of text files, ROOT files, gtlike source-model files (for LAT maximum likelihood analyses), and PHA I/II FITS files (for RMFit/XSpec spectral fitting analyses). Its core is written in C++ and its user interface in Python.

  13. Moving object detection using background subtraction

    CERN Document Server

    Shaikh, Soharab Hossain; Chaki, Nabendu

    2014-01-01

    This Springer Brief presents a comprehensive survey of the existing methodologies of background subtraction methods. It presents a framework for quantitative performance evaluation of different approaches and summarizes the public databases available for research purposes. This well-known methodology has applications in moving object detection from video captured with a stationery camera, separating foreground and background objects and object classification and recognition. The authors identify common challenges faced by researchers including gradual or sudden illumination change, dynamic bac

  14. Robust Background Subtraction with Incremental Eigen Models

    OpenAIRE

    Gritti, T.

    2008-01-01

    In this report we first describe a background subtraction algorithm based on the use of eigen space decomposition. We then present a method to achive incremental modelling, which allows for faster computation and saving in memory requirements. We discuss the performanceof the algorithm and the issues related to the choice of parametersin details. We also provide a description of a real-time implementation which allows to update a model while being able to operate background subtraction at the...

  15. In-beam background suppression shield

    DEFF Research Database (Denmark)

    Santoro, V.; Cai, Xiao Xiao; DiJulio, D. D.

    2015-01-01

    , which do not use a bender to help mitigate the fast neutron background, are the most challenging. For these beam lines we propose the innovative shielding of placing blocks of material directly into the guide system, which allow a minimum attenuation of the cold and thermal fluxes relative...... to the background suppression. This shielding configuration has been worked into a beam line model using Geant4. We study particularly the advantages of single crystal sapphire and silicon blocks....

  16. Background Modelling Using Edge-Segment Distributions

    Directory of Open Access Journals (Sweden)

    Jaemyun Kim

    2013-02-01

    Full Text Available We propose an edge-segment-based statistical background modelling algorithm to detect the moving edges for the detection of moving objects using a static camera. Traditional pixel intensity-based background modelling algorithms face difficulties in dynamic environments since they cannot handle sudden changes in illumination. They also bring out ghosts when a sudden change occurs in the scene. To cope with this issue, intensity and noise robust edge-based features have emerged. However, existing edge-pixel-based methods suffer from scattered moving edge pixels since they cannot utilize the shape. Moreover, traditional segment-based methods cannot handle edge shape variations and miss moving edges when they come close to the background edges. Unlike traditional approaches, our proposed method builds the background model from ordinary training frames that may contain moving objects. Furthermore, it does not leave any ghosts behind. Moreover, our method uses an automatic threshold for every background edge distribution for matching. This makes our approach robust to illumination change, camera movement and background motion. Experiments show that our method outperforms others and can detect moving edges efficiently despite the above mentioned difficulties.

  17. Aircraft and background noise annoyance effects

    Science.gov (United States)

    Willshire, K. F.

    1984-01-01

    To investigate annoyance of multiple noise sources, two experiments were conducted. The first experiment, which used 48 subjects, was designed to establish annoyance-noise level functions for three community noise sources presented individually: jet aircraft flyovers, air conditioner, and traffic. The second experiment, which used 216 subjects, investigated the effects of background noise on aircraft annoyance as a function of noise level and spectrum shape; and the differences between overall, aircraft, and background noise annoyance. In both experiments, rated annoyance was the dependent measure. Results indicate that the slope of the linear relationship between annoyance and noise level for traffic is significantly different from that of flyover and air conditioner noise and that further research was justified to determine the influence of the two background noises on overall, aircraft, and background noise annoyance (e.g., experiment two). In experiment two, total noise exposure, signal-to-noise ratio, and background source type were found to have effects on all three types of annoyance. Thus, both signal-to-noise ratio, and the background source must be considered when trying to determine community response to combined noise sources.

  18. Ultra-Low Background Measurements Of Decayed Aerosol Filters

    Science.gov (United States)

    Miley, H.

    2009-04-01

    To experimentally evaluate the opportunity to apply ultra-low background measurement methods to samples collected, for instance, by the Comprehensive Test Ban Treaty International Monitoring System (IMS), aerosol samples collected on filter media were measured using HPGe spectrometers of varying low-background technology approaches. In this way, realistic estimates of the impact of low-background methodology can be assessed on the Minimum Detectable Activities obtained in systems such as the IMS. The current measurement requirement of stations in the IMS is 30 microBq per cubic meter of air for 140Ba, or about 106 fissions per daily sample. Importantly, this is for a fresh aerosol filter. Decay varying form 3 days to one week reduce the intrinsic background from radon daughters in the sample. Computational estimates of the improvement factor for these decayed filters for underground-based HPGe in clean shielding materials are orders of magnitude less, even when the decay of the isotopes of interest is included.

  19. Diminished Reality Based on Image Inpainting Considering Background Geometry.

    Science.gov (United States)

    Kawai, Norihiko; Sato, Tomokazu; Yokoya, Naokazu

    2016-03-01

    Diminished reality aims to remove real objects from video images and fill in the missing regions with plausible background textures in real time. Most conventional methods based on image inpainting achieve diminished reality by assuming that the background around a target object is almost planar. This paper proposes a new diminished reality method that considers background geometries with less constraints than the conventional ones. In this study, we approximate the background geometry by combining local planes, and improve the quality of image inpainting by correcting the perspective distortion of texture and limiting the search area for finding similar textures as exemplars. The temporal coherence of texture is preserved using the geometries and camera pose estimated by visual-simultaneous localization and mapping (SLAM). The mask region that includes a target object is robustly set in each frame by projecting a 3D region, rather than tracking the object in 2D image space. The effectiveness of the proposed method is successfully demonstrated using several experimental environments.

  20. Automatic moving-object and background segmentation by means of higher order statistics

    Science.gov (United States)

    Neri, Alessandro; Colonnese, Stefania; Russo, Giuseppe

    1997-01-01

    In this paper we propose a segmentation method aimed at separating the moving objects from the background in a generic video sequence. This task, accomplished at the coder site, is intended to support some new functionalities oriented to access and decode single objects of the coded video sequence, foreseen by innovative multimedia scenarios focused during the MPEG4 work. The proposed segmentation method comprises a motion detection, that produces a preliminary segmentation map, followed by a morphological regularization that plays an important role in eliminating misclassifications due to motion estimation ambiguities, noise, etc., of the original video sequence. The motion detection is essentially based on a higher order statistics (HOS) test that employs a temporally, non-linearly filtered version of the video sequence; this choice is motivated by HOS detection properties. The regularization phase, performed by basic morphological operators, provides a local connectivity constraint on the background-foreground map. The segmentation algorithm performance is illustrated by some experimental results carried out on MPEG4 test sequences.

  1. Physical Activity and School Absenteeism Due to Illness in Adolescents

    Science.gov (United States)

    de Groot, Renate; van Dijk, Martin; Savelberg, Hans; van Acker, Frederik; Kirschner, Paul

    2017-01-01

    Background: Knowledge about the beneficial role of physical activity (PA) for health and school performance is growing. Studies investigating the link between PA and school absenteeism due to illness are lacking. Therefore, we investigated associations between habitual PA and school absenteeism due to illness in adolescents and explored whether…

  2. Experimental philosophy.

    Science.gov (United States)

    Knobe, Joshua; Buckwalter, Wesley; Nichols, Shaun; Robbins, Philip; Sarkissian, Hagop; Sommers, Tamler

    2012-01-01

    Experimental philosophy is a new interdisciplinary field that uses methods normally associated with psychology to investigate questions normally associated with philosophy. The present review focuses on research in experimental philosophy on four central questions. First, why is it that people's moral judgments appear to influence their intuitions about seemingly nonmoral questions? Second, do people think that moral questions have objective answers, or do they see morality as fundamentally relative? Third, do people believe in free will, and do they see free will as compatible with determinism? Fourth, how do people determine whether an entity is conscious?

  3. Low energy neutron background in deep underground laboratories

    Energy Technology Data Exchange (ETDEWEB)

    Best, Andreas, E-mail: andreas.best@lngs.infn.it [INFN, Laboratori Nazionali del Gran Sasso (LNGS), 67100 Assergi (Italy); Department of Physics and The Joint Institute for Nuclear Astrophysics, University of Notre Dame, Notre Dame, IN 46556 (United States); Görres, Joachim [Department of Physics and The Joint Institute for Nuclear Astrophysics, University of Notre Dame, Notre Dame, IN 46556 (United States); Junker, Matthias [INFN, Laboratori Nazionali del Gran Sasso (LNGS), 67100 Assergi (Italy); Kratz, Karl-Ludwig [Department for Biogeochemistry, Max-Planck-Institute for Chemistry, 55020 Mainz (Germany); Laubenstein, Matthias [INFN, Laboratori Nazionali del Gran Sasso (LNGS), 67100 Assergi (Italy); Long, Alexander [Department of Physics and The Joint Institute for Nuclear Astrophysics, University of Notre Dame, Notre Dame, IN 46556 (United States); Nisi, Stefano [INFN, Laboratori Nazionali del Gran Sasso (LNGS), 67100 Assergi (Italy); Smith, Karl; Wiescher, Michael [Department of Physics and The Joint Institute for Nuclear Astrophysics, University of Notre Dame, Notre Dame, IN 46556 (United States)

    2016-03-11

    The natural neutron background influences the maximum achievable sensitivity in most deep underground nuclear, astroparticle and double-beta decay physics experiments. Reliable neutron flux numbers are an important ingredient in the design of the shielding of new large-scale experiments as well as in the analysis of experimental data. Using a portable setup of {sup 3}He counters we measured the thermal neutron flux at the Kimballton Underground Research Facility, the Soudan Underground Laboratory, on the 4100 ft and the 4850 ft levels of the Sanford Underground Research Facility, at the Waste Isolation Pilot Plant and at the Gran Sasso National Laboratory. Absolute neutron fluxes at these laboratories are presented.

  4. $\\sigma(600)$ and background in $\\pi\\pi$ scattering

    OpenAIRE

    Kaloshin, A. E.; Persikov, V. M.; Vall, A. N.

    2003-01-01

    We suggest a simple analytical description of the S-wave isoscalar $\\pi\\pi$ amplitude, which corresponds to a joint dressing of the bare resonance and background contributions. The amplitude describes well the experimental data on the $\\delta^0_0$ phase shift in the energy region below 900 MeV and has two poles in the $Re s > 0$ half-plane. Besides the well-known pole of $\\sigma(600)$-meson with $Re s \\sim m_{\\pi}^2$, there exists a more distant pole with $Re s \\sim 0.6 GeV^2$. Our analysis i...

  5. Top-Down and Bottom-Up Cues Based Moving Object Detection for Varied Background Video Sequences

    Directory of Open Access Journals (Sweden)

    Chirag I. Patel

    2014-01-01

    there is no need for background formulation and updates as it is background independent. Many bottom-up approaches and one combination of bottom-up and top-down approaches are proposed in the present paper. The proposed approaches seem more efficient due to inessential requirement of learning background model and due to being independent of previous video frames. Results indicate that the proposed approach works even against slight movements in the background and in various outdoor conditions.

  6. Background Noise Reduction Using Adaptive Noise Cancellation Determined by the Cross-Correlation

    Science.gov (United States)

    Spalt, Taylor B.; Brooks, Thomas F.; Fuller, Christopher R.

    2012-01-01

    Background noise due to flow in wind tunnels contaminates desired data by decreasing the Signal-to-Noise Ratio. The use of Adaptive Noise Cancellation to remove background noise at measurement microphones is compromised when the reference sensor measures both background and desired noise. The technique proposed modifies the classical processing configuration based on the cross-correlation between the reference and primary microphone. Background noise attenuation is achieved using a cross-correlation sample width that encompasses only the background noise and a matched delay for the adaptive processing. A present limitation of the method is that a minimum time delay between the background noise and desired signal must exist in order for the correlated parts of the desired signal to be separated from the background noise in the crosscorrelation. A simulation yields primary signal recovery which can be predicted from the coherence of the background noise between the channels. Results are compared with two existing methods.

  7. Pythia Jet Finding Study with Trento Backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Joseph [United States Naval Academy, Annapolis, MD (United States); Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States); Soltz, Ron [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2016-06-22

    We present results applying the Pythia SlowJet Finder to Pythia generated QCD and QED hard processes in the presence of simulated heavy ion backgrounds. The hard process events are generated with Pythia version 8.219 for √sNN=200 GeV proton-proton collisions and the backgrounds are generated by the Reduced Thickness Event-by-event Nuclear Topology model TRENTo for Au-Au collisions with a nucleon-nucleon cross-section of 4.23 fm2. The TRENTo model is used to calculate the initial entropy and ellipticity from which the total charged particle multiplicity and elliptic ow are determined. We report results in the form of event displays, total pT distributions, and fragmentation distributions for SlowJet applied to Pythia events with and without the simulated heavy ion backgrounds.

  8. Background Rejection in the ARA Experiment

    Directory of Open Access Journals (Sweden)

    Pfendner Carl

    2017-01-01

    Full Text Available The Askaryan Radio Array (ARA is a radio frequency observatory under construction at the South Pole that is searching for ultrahigh energy neutrinos via the Askaryan effect. Thermal fluctuations currently dominate the trigger-level background for the observatory and anthropogenic sources also introduce a significant source of noise. By taking advantage of the observatory’s regular geometry and the expected coincident nature of the RF signals arriving from neutrino-induced events, this background can be filtered efficiently. This contribution will discuss techniques developed for the ARA analyses to reject these thermal signals, to reject anthropogenic backgrounds, and to search for neutrino-induced particle showers in the Antarctic ice. The results of a search for neutrinos from GRBs using the prototype station using some of these techniques will be presented.

  9. Influence of paroxysmal activity on background synchronization in epileptic recordings.

    Science.gov (United States)

    Pastor, Jesús; Sola, Rafael G; Ortega, Guillermo J

    2014-02-15

    The presence of spikes and sharp waves in recordings of epileptic patients contaminates background signal synchronization. When estimating functional connectivity between extended cortical areas, the influence of epileptic spikes in specific areas should be considered; however, this step is sometimes overlooked. We present a simple method for quantifying the influence of epileptic activity on background signal synchronization. Standard synchronization measures were calculated for both pure correlated Gaussian signals and correlated Gaussian signals with different levels of epileptic spikes in order to determine the influence of epileptic activity on synchronization estimates. Synchronization from invasive epileptic recordings (e.g., depth electrodes) displays a much higher bias due to epileptic activity than superficial electrodes. Moreover, statistical methods such as mutual information are more affected by spike presence than phase synchronization methods. The influence of spikes is far greater at low values of background synchronization. The information provided by this procedure makes it possible to differentiate true background synchronization from spike synchronization. Thus, our procedure serves as a guide for analyzing synchronization and functional connectivity calculations in epileptic recordings. Copyright © 2013 Elsevier B.V. All rights reserved.

  10. Cognitive test performance and background music.

    Science.gov (United States)

    Cockerton, T; Moore, S; Norman, D

    1997-12-01

    This study examined the effects of background music on test performance. In a repeated-measures design 30 undergraduates completed two cognitive tests, one in silence and the other with background music. Analysis suggested that music facilitated cognitive performance compared with the control condition of no music: more questions were completed and more answers were correct. There was no difference in heart rate under the two conditions. The improved performance under the music condition might be directly related to the type of music used.

  11. The ROSAT X-ray Background Dipole

    OpenAIRE

    Plionis, M.; Georgantopoulos, I.

    1998-01-01

    We estimate the dipole of the diffuse 1.5 keV X-ray background from the ROSAT all-sky survey map of Snowden et al (1995). We first subtract the diffuse Galactic emission by fitting to the data an exponential scale height, finite radius, disk model. We further exclude regions of low galactic latitudes, of local X-ray emission (eg the North Polar Spur) and model them using two different methods. We find that the ROSAT X-ray background (XRB) dipole points towards $(l,b) ~ (288, 25) \\pm 19 degree...

  12. Verbal learning in the context of background music: no influence of vocals and instrumentals on verbal learning

    OpenAIRE

    Jäncke, Lutz; Brügger, Eliane; Brummer, Moritz; Scherrer, Stephanie; Alahmadi, Nsreen

    2014-01-01

    BACKGROUND: Whether listening to background music enhances verbal learning performance is still a matter of dispute. In this study we investigated the influence of vocal and instrumental background music on verbal learning. METHODS: 226 subjects were randomly assigned to one of five groups (one control group and 4 experimental groups). All participants were exposed to a verbal learning task. One group served as control group while the 4 further groups served as experimental groups. The con...

  13. Verbal learning in the context of background music: no influence of vocals and instrumentals on verbal learning.

    OpenAIRE

    Jancke L.; Brugger E; Brummer M.; Scherrer S; Alahmadi N

    2014-01-01

    BACKGROUND: Whether listening to background music enhances verbal learning performance is still a matter of dispute. In this study we investigated the influence of vocal and instrumental background music on verbal learning. METHODS: 226 subjects were randomly assigned to one of five groups (one control group and 4 experimental groups). All participants were exposed to a verbal learning task. One group served as control group while the 4 further groups served as experimental groups. The contro...

  14. Cosmic Microwave Background Anisotropies up to Second Order

    CERN Document Server

    Bartolo, Nicola; Riotto, Antonio

    2007-01-01

    These lecture notes present the computation of the full system of Boltzmann equations describing the evolution of the photon, baryon and cold dark matter fluids up to second order in perturbation theory, as recently studied in (Bartolo, Matarrese & Riotto 2006, 2007). These equations allow to follow the time evolution of the cosmic microwave background anisotropies at all angular scales from the early epoch, when the cosmological perturbations were generated, to the present, through the recombination era. The inclusion of second-order contributions is mandatory when one is interested in studying possible deviations from Gaussianity of cosmological perturbations, either of primordial (e.g. inflationary) origin or due to their subsequent evolution. Most of the emphasis in these lectures notes will be given to the derivation of the relevant equations for the study of cosmic microwave background anisotropies and to their analytical solutions.

  15. Background based Gaussian mixture model lesion segmentation in PET

    Energy Technology Data Exchange (ETDEWEB)

    Soffientini, Chiara Dolores, E-mail: chiaradolores.soffientini@polimi.it; Baselli, Giuseppe [DEIB, Department of Electronics, Information, and Bioengineering, Politecnico di Milano, Piazza Leonardo da Vinci 32, Milan 20133 (Italy); De Bernardi, Elisabetta [Department of Medicine and Surgery, Tecnomed Foundation, University of Milano—Bicocca, Monza 20900 (Italy); Zito, Felicia; Castellani, Massimo [Nuclear Medicine Department, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, via Francesco Sforza 35, Milan 20122 (Italy)

    2016-05-15

    Purpose: Quantitative {sup 18}F-fluorodeoxyglucose positron emission tomography is limited by the uncertainty in lesion delineation due to poor SNR, low resolution, and partial volume effects, subsequently impacting oncological assessment, treatment planning, and follow-up. The present work develops and validates a segmentation algorithm based on statistical clustering. The introduction of constraints based on background features and contiguity priors is expected to improve robustness vs clinical image characteristics such as lesion dimension, noise, and contrast level. Methods: An eight-class Gaussian mixture model (GMM) clustering algorithm was modified by constraining the mean and variance parameters of four background classes according to the previous analysis of a lesion-free background volume of interest (background modeling). Hence, expectation maximization operated only on the four classes dedicated to lesion detection. To favor the segmentation of connected objects, a further variant was introduced by inserting priors relevant to the classification of neighbors. The algorithm was applied to simulated datasets and acquired phantom data. Feasibility and robustness toward initialization were assessed on a clinical dataset manually contoured by two expert clinicians. Comparisons were performed with respect to a standard eight-class GMM algorithm and to four different state-of-the-art methods in terms of volume error (VE), Dice index, classification error (CE), and Hausdorff distance (HD). Results: The proposed GMM segmentation with background modeling outperformed standard GMM and all the other tested methods. Medians of accuracy indexes were VE <3%, Dice >0.88, CE <0.25, and HD <1.2 in simulations; VE <23%, Dice >0.74, CE <0.43, and HD <1.77 in phantom data. Robustness toward image statistic changes (±15%) was shown by the low index changes: <26% for VE, <17% for Dice, and <15% for CE. Finally, robustness toward the user-dependent volume initialization was

  16. Background model for the Majorana Demonstrator

    Science.gov (United States)

    Cuesta, C.; Majorana Collaboration

    2017-09-01

    The Majorana Collaboration is constructing a system containing 44 kg of high-purity Ge (HPGe) detectors to demonstrate the feasibility and potential of a future tonne-scale experiment capable of probing the neutrino mass scale to ∼15 meV. To realize this, a major goal of the Majorana Demonstrator is to demonstrate a path forward to achieving a background rate at or below 1 count/(ROI-t-y) in the 4 keV region of interest (ROI) around the Q-value at 2039 keV. This goal is pursued through a combination of a significant reduction of radioactive impurities in construction materials and analytical methods for background rejection, for example using powerful pulse shape analysis techniques profiting from the p-type point contact (PPC) HPGe detectors technology. The effectiveness of these methods is assessed using simulations of the different background components whose purity levels are constrained from radioassay measurements. Preliminary background results obtained during the engineering runs of the Demonstrator are presented.

  17. 16 CFR 1031.17 - Background.

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 2 2010-01-01 2010-01-01 false Background. 1031.17 Section 1031.17 Commercial Practices CONSUMER PRODUCT SAFETY COMMISSION GENERAL COMMISSION PARTICIPATION AND COMMISSION... that it was launching a pilot program to open CPSC staff activities for public review and comment. The...

  18. 36 CFR 805.1 - Background.

    Science.gov (United States)

    2010-07-01

    ... to the environmental effects of their proposed actions in their decisionmaking and to prepare detailed environmental statements on recommendations or reports on proposals for legislation and other... IMPLEMENTATION OF NATIONAL ENVIRONMENTAL POLICY ACT § 805.1 Background. (a) The National Environmental Policy Act...

  19. Racial background and possible relationships between physical ...

    African Journals Online (AJOL)

    The aim of this research was to investigate possible relationships between physical activity and physical fitness of girls between the ages of 13 and 15 years and the role of different racial backgrounds in this relationship. A cross-sectional research design was used to obtain information from 290 girls between the ages of 13 ...

  20. Bloemfontein's Greek community: historical background, emigration ...

    African Journals Online (AJOL)

    Where possible, it is also indicated who they were. Their settlement in Bloemfontein is sketched against the background of the development of Bloemfontein as a city. In the light of the fact that thus far almost nothing has been written about the Greek community in Bloemfontein, and few archival sources could be traced, the

  1. Anomalies of the Cosmic Microwave Background

    DEFF Research Database (Denmark)

    Hansen, Martin Anders Kirstejn

    The Cosmic Microwave Background (CMB) is the faint afterglow of the extreme conditions that existed shortly after Big Bang. The temperature of the CMB radiation across the sky is extremely uniform, yet tiny anisotropies are present, and have with recent satellite missions been mapped to very high...

  2. Does Social Background Influence Political Science Grades?

    Science.gov (United States)

    Tiruneh, Gizachew

    2013-01-01

    This paper tests a hypothesized linear relationship between social background and final grades in several political science courses that I taught at the University of Central Arkansas. I employ a cross-sectional research design and ordinary least square (OLS) estimators to test the foregoing hypothesis. Relying on a sample of up to 204…

  3. Koenderink filters and the Microwave Background

    OpenAIRE

    Schmalzing, Jens

    1997-01-01

    We introduce Koenderink filters as novel tools for statistical cosmology. Amongst several promising applications, they provide a test for the Gaussianity of random fields. We focus on this application and present some preliminary results from an analysis of the Cosmic Microwave Background (CMB).

  4. 40 CFR 105.1 - Background.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Background. 105.1 Section 105.1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS RECOGNITION AWARDS UNDER... the preceding year demonstrated an outstanding technological achievement or an innovative process...

  5. The projected background for the CUORE experiment

    Energy Technology Data Exchange (ETDEWEB)

    Alduino, C.; Avignone, F.T.; Chott, N.; Creswick, R.J.; Rosenfeld, C.; Wilson, J. [University of South Carolina, Department of Physics and Astronomy, Columbia, SC (United States); Alfonso, K.; Hickerson, K.P.; Huang, H.Z.; Sakai, M.; Schmidt, J.; Trentalange, S.; Zhu, B.X. [University of California, Department of Physics and Astronomy, Los Angeles, CA (United States); Artusa, D.R.; Rusconi, C. [University of South Carolina, Department of Physics and Astronomy, Columbia, SC (United States); INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); Azzolini, O.; Camacho, A.; Keppel, G.; Palmieri, V.; Pira, C. [INFN-Laboratori Nazionali di Legnaro, Padua (Italy); Banks, T.I.; Drobizhev, A.; Freedman, S.J.; Hennings-Yeomans, R.; Kolomensky, Yu.G.; Wagaarachchi, S.L. [University of California, Department of Physics, Berkeley, CA (United States); Lawrence Berkeley National Laboratory, Nuclear Science Division, Berkeley, CA (United States); Bari, G.; Deninno, M.M. [INFN-Sezione di Bologna, Bologna (Italy); Beeman, J.W. [Lawrence Berkeley National Laboratory, Materials Science Division, Berkeley, CA (United States); Bellini, F.; Cosmelli, C.; Ferroni, F.; Piperno, G. [Sapienza Universita di Roma, Dipartimento di Fisica, Rome (Italy); INFN-Sezione di Roma, Rome (Italy); Benato, G.; Singh, V. [University of California, Department of Physics, Berkeley, CA (United States); Bersani, A.; Caminata, A. [INFN-Sezione di Genova, Genoa (Italy); Biassoni, M.; Brofferio, C.; Capelli, S.; Carniti, P.; Cassina, L.; Chiesa, D.; Clemenza, M.; Faverzani, M.; Fiorini, E.; Gironi, L.; Gotti, C.; Maino, M.; Nastasi, M.; Nucciotti, A.; Pavan, M.; Pozzi, S.; Sisti, M.; Terranova, F.; Zanotti, L. [Universita di Milano-Bicocca, Dipartimento di Fisica, Milan (Italy); INFN-Sezione di Milano Bicocca, Milan (Italy); Branca, A.; Taffarello, L. [INFN-Sezione di Padova, Padua (Italy); Bucci, C.; Cappelli, L.; D' Addabbo, A.; Gorla, P.; Pattavina, L.; Pirro, S.; Laubenstein, M. [INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); Canonica, L. [INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); Massachusetts Institute of Technology, Cambridge, MA (United States); Cao, X.G.; Fang, D.Q.; Ma, Y.G.; Wang, H.W.; Zhang, G.Q. [Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai (China); Carbone, L.; Cremonesi, O.; Ferri, E.; Giachero, A.; Pessina, G.; Previtali, E. [INFN-Sezione di Milano Bicocca, Milan (Italy); Cardani, L.; Casali, N.; Dafinei, I.; Morganti, S.; Mosteiro, P.J.; Pettinacci, V.; Tomei, C.; Vignati, M. [INFN-Sezione di Roma, Rome (Italy); Copello, S.; Di Domizio, S.; Fernandes, G.; Marini, L.; Pallavicini, M. [INFN-Sezione di Genova, Genoa (Italy); Universita di Genova, Dipartimento di Fisica, Genoa (Italy); Cushman, J.S.; Davis, C.J.; Heeger, K.M.; Lim, K.E.; Maruyama, R.H. [Yale University, Department of Physics, New Haven, CT (United States); Dell' Oro, S. [INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); INFN-Gran Sasso Science Institute, L' Aquila (Italy); Di Vacri, M.L.; Santone, D. [INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); Universita dell' Aquila, Dipartimento di Scienze Fisiche e Chimiche, L' Aquila (Italy); Franceschi, M.A.; Ligi, C.; Napolitano, T. [INFN-Laboratori Nazionali di Frascati, Rome (Italy); Fujikawa, B.K.; Mei, Y.; Schmidt, B.; Smith, A.R.; Welliver, B. [Lawrence Berkeley National Laboratory, Nuclear Science Division, Berkeley, CA (United States); Giuliani, A.; Novati, V.; Tenconi, M. [Universit Paris-Saclay, CSNSM, Univ. Paris-Sud, CNRS/IN2P3, Orsay (France); Gladstone, L.; Leder, A.; Ouellet, J.L.; Winslow, L.A. [Massachusetts Institute of Technology, Cambridge, MA (United States); Gutierrez, T.D. [California Polytechnic State University, Physics Department, San Luis Obispo, CA (United States); Haller, E.E. [Lawrence Berkeley National Laboratory, Materials Science Division, Berkeley, CA (United States); University of California, Department of Materials Science and Engineering, Berkeley, CA (United States); Han, K. [Shanghai Jiao Tong University, Department of Physics and Astronomy, Shanghai (China); Hansen, E. [University of California, Department of Physics and Astronomy, Los Angeles, CA (United States); Massachusetts Institute of Technology, Cambridge, MA (United States); Kadel, R. [Lawrence Berkeley National Laboratory, Physics Division, Berkeley, CA (United States); Martinez, M. [Sapienza Universita di Roma, Dipartimento di Fisica, Rome (Italy); INFN-Sezione di Roma, Rome (Italy); Universidad de Zaragoza, Laboratorio de Fisica Nuclear y Astroparticulas, Zaragoza (Spain); Moggi, N. [INFN-Sezione di Bologna, Bologna (Italy); Alma Mater Studiorum-Universita di Bologna, Dipartimento di Scienze per la Qualita della Vita, Bologna (Italy); Nones, C. [CEA/Saclay, Service de Physique des Particules, Gif-sur-Yvette (France); Norman, E.B.; Wang, B.S. [Lawrence Livermore National Laboratory, Livermore, CA (United States); University of California, Department of Nuclear Engineering, Berkeley, CA (United States); O' Donnell, T. [Virginia Polytechnic Institute and State University, Center for Neutrino Physics, Blacksburg, VA (United States); Pagliarone, C.E. [INFN-Laboratori Nazionali del Gran Sasso, L' Aquila (Italy); Universita degli Studi di Cassino e del Lazio Meridionale, Dipartimento di Ingegneria Civile e Meccanica, Cassino (Italy); Sangiorgio, S.; Scielzo, N.D. [Lawrence Livermore National Laboratory, Livermore, CA (United States); Wise, T. [Yale University, Department of Physics, New Haven, CT (United States); University of Wisconsin, Department of Physics, Madison, WI (United States); Woodcraft, A. [University of Edinburgh, SUPA, Institute for Astronomy, Edinburgh (United Kingdom); Zimmermann, S. [Lawrence Berkeley National Laboratory, Engineering Division, Berkeley, CA (United States); Zucchelli, S. [INFN-Sezione di Bologna, Bologna (Italy); Alma Mater Studiorum-Universita di Bologna, Dipartimento di Fisica e Astronomia, Bologna (Italy)

    2017-08-15

    The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of {sup 130}Te with an array of 988 TeO{sub 2} bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90% C.L. exclusion sensitivity on the {sup 130}Te decay half-life of 9 x 10{sup 25} years after 5 years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10{sup -2} counts/keV/kg/year. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of {sup 130}Te is expected. (orig.)

  6. The projected background for the CUORE experiment

    Science.gov (United States)

    Alduino, C.; Alfonso, K.; Artusa, D. R.; Avignone, F. T.; Azzolini, O.; Banks, T. I.; Bari, G.; Beeman, J. W.; Bellini, F.; Benato, G.; Bersani, A.; Biassoni, M.; Branca, A.; Brofferio, C.; Bucci, C.; Camacho, A.; Caminata, A.; Canonica, L.; Cao, X. G.; Capelli, S.; Cappelli, L.; Carbone, L.; Cardani, L.; Carniti, P.; Casali, N.; Cassina, L.; Chiesa, D.; Chott, N.; Clemenza, M.; Copello, S.; Cosmelli, C.; Cremonesi, O.; Creswick, R. J.; Cushman, J. S.; D'Addabbo, A.; Dafinei, I.; Davis, C. J.; Dell'Oro, S.; Deninno, M. M.; Di Domizio, S.; Di Vacri, M. L.; Drobizhev, A.; Fang, D. Q.; Faverzani, M.; Fernandes, G.; Ferri, E.; Ferroni, F.; Fiorini, E.; Franceschi, M. A.; Freedman, S. J.; Fujikawa, B. K.; Giachero, A.; Gironi, L.; Giuliani, A.; Gladstone, L.; Gorla, P.; Gotti, C.; Gutierrez, T. D.; Haller, E. E.; Han, K.; Hansen, E.; Heeger, K. M.; Hennings-Yeomans, R.; Hickerson, K. P.; Huang, H. Z.; Kadel, R.; Keppel, G.; Kolomensky, Yu. G.; Leder, A.; Ligi, C.; Lim, K. E.; Ma, Y. G.; Maino, M.; Marini, L.; Martinez, M.; Maruyama, R. H.; Mei, Y.; Moggi, N.; Morganti, S.; Mosteiro, P. J.; Napolitano, T.; Nastasi, M.; Nones, C.; Norman, E. B.; Novati, V.; Nucciotti, A.; O'Donnell, T.; Ouellet, J. L.; Pagliarone, C. E.; Pallavicini, M.; Palmieri, V.; Pattavina, L.; Pavan, M.; Pessina, G.; Pettinacci, V.; Piperno, G.; Pira, C.; Pirro, S.; Pozzi, S.; Previtali, E.; Rosenfeld, C.; Rusconi, C.; Sakai, M.; Sangiorgio, S.; Santone, D.; Schmidt, B.; Schmidt, J.; Scielzo, N. D.; Singh, V.; Sisti, M.; Smith, A. R.; Taffarello, L.; Tenconi, M.; Terranova, F.; Tomei, C.; Trentalange, S.; Vignati, M.; Wagaarachchi, S. L.; Wang, B. S.; Wang, H. W.; Welliver, B.; Wilson, J.; Winslow, L. A.; Wise, T.; Woodcraft, A.; Zanotti, L.; Zhang, G. Q.; Zhu, B. X.; Zimmermann, S.; Zucchelli, S.; Laubenstein, M.

    2017-08-01

    The Cryogenic Underground Observatory for Rare Events (CUORE) is designed to search for neutrinoless double beta decay of ^{130}Te with an array of 988 TeO_2 bolometers operating at temperatures around 10 mK. The experiment is currently being commissioned in Hall A of Laboratori Nazionali del Gran Sasso, Italy. The goal of CUORE is to reach a 90% C.L. exclusion sensitivity on the ^{130}Te decay half-life of 9 × 10^{25} years after 5 years of data taking. The main issue to be addressed to accomplish this aim is the rate of background events in the region of interest, which must not be higher than 10^{-2} counts/keV/kg/year. We developed a detailed Monte Carlo simulation, based on results from a campaign of material screening, radioassays, and bolometric measurements, to evaluate the expected background. This was used over the years to guide the construction strategies of the experiment and we use it here to project a background model for CUORE. In this paper we report the results of our study and our expectations for the background rate in the energy region where the peak signature of neutrinoless double beta decay of ^{130}Te is expected.

  7. Probabilistic Model-Based Background Subtraction

    DEFF Research Database (Denmark)

    Krüger, Volker; Andersen, Jakob; Prehn, Thomas

    2005-01-01

    manner. Bayesian propagation over time is used for proper model selection and tracking during model-based background subtraction. Bayes propagation is attractive in our application as it allows to deal with uncertainties during tracking. We have tested our approach on suitable outdoor video data....

  8. Background reduction in a young interferometer biosensor

    NARCIS (Netherlands)

    Mulder, H. K P; Subramaniam, V.; Kanger, J. S.

    2014-01-01

    Integrated optical Young interferometer (IOYI) biosensors are among the most sensitive label-free biosensors. Detection limits are in the range of 20 fg/mm2. The applicability of these sensors is however strongly hampered by the large background that originates from both bulk refractive index

  9. Spinal cord stimulation: Background and clinical application

    DEFF Research Database (Denmark)

    Meier, Kaare

    2014-01-01

    a number of contacts capable of delivering a weak electrical current to the spinal cord, evoking a feeling of peripheral paresthesia. With correct indication and if implanted by an experienced implanter, success rates generally are in the range of about 50–75%. Common indications include complex regional...... and theoretical background, practical implantation technique, and clinical application....

  10. Computer Software & Intellectual Property. Background Paper.

    Science.gov (United States)

    Congress of the U.S., Washington, DC. Office of Technology Assessment.

    This background paper reviews copyright, patent, and trade secret protections as these issues are related to computer software. Topics discussed include current issues regarding legal protection for computer software including the necessity for defining intellectual property, determining what should or should not be protected, commerical piracy,…

  11. 23 CFR 777.3 - Background.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Background. 777.3 Section 777.3 Highways FEDERAL HIGHWAY ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RIGHT-OF-WAY AND ENVIRONMENT MITIGATION OF IMPACTS TO WETLANDS AND... use of ecological mitigation banks as compensatory mitigation in the Section 404 Regulatory Program...

  12. Climate change. Scientific background and process

    Energy Technology Data Exchange (ETDEWEB)

    Alfsen, Knut H.; Fuglestvedt, Jan; Seip, Hans Martin; Skodvin, Tora

    1999-07-01

    The paper describes briefly the natural and man-made forces behind climate change and outlines climate variations in the past. It also discusses the future impact of anthropogenic emission of greenhouse gases, and the background, organisation and functioning of the Intergovernmental Panel on Climate Change (IPCC)

  13. REQUEST FOR EXPRESSIONS OF INTEREST For Background ...

    International Development Research Centre (IDRC) Digital Library (Canada)

    sbickram

    2012-07-10

    Jul 10, 2012 ... Submission of report for publication in a peer-reviewed journal (month 5-7). Methodology. Each background study will consist of a review of the scientific literature and a scan of grey literature. (policy documents, reports, web resources, etc.) to identify key cross-cutting issues for consideration in the design ...

  14. 47 CFR 215.1 - Background.

    Science.gov (United States)

    2010-10-01

    ... Force, and DOE laboratories on matters concerning nuclear weapons, nuclear weapons effects, and nuclear... POINT FOR ELECTROMAGNETIC PULSE (EMP) INFORMATION § 215.1 Background. (a) The nuclear electromagnetic pulse (EMP) is part of the complex environment produced by nuclear explosions. It consists of transient...

  15. Infrared clutter measurements of marine backgrounds

    NARCIS (Netherlands)

    Schwering, Piet B.

    1991-01-01

    Observations in the infrared wavelength band between 8 and 12 μm of sea backgrounds have been recorded with a CCIR compatible imager for a large number of sea states (0 - 6). Recordings took place in coastal areas as well as on open seas. The behavior of clutter in the infrared data was analyzed in

  16. Animal experimentation.

    Science.gov (United States)

    Kolar, Roman

    2006-01-01

    Millions of animals are used every year in often times extremely painful and distressing scientific procedures. Legislation of animal experimentation in modern societies is based on the supposition that this is ethically acceptable when certain more or less defined formal (e.g. logistical, technical) demands and ethical principles are met. The main parameters in this context correspond to the "3Rs" concept as defined by Russel and Burch in 1959, i.e. that all efforts to replace, reduce and refine experiments must be undertaken. The licensing of animal experiments normally requires an ethical evaluation process, often times undertaken by ethics committees. The serious problems in putting this idea into practice include inter alia unclear conditions and standards for ethical decisions, insufficient management of experiments undertaken for specific (e.g. regulatory) purposes, and conflicts of interest of ethics committees' members. There is an ongoing societal debate about ethical issues of animal use in science. Existing EU legislation on animal experimentation for cosmetics testing is an example of both the public will for setting clear limits to animal experiments and the need to further critically examine other fields and aspects of animal experimentation.

  17. X-Ray Background from Early Binaries

    Science.gov (United States)

    Kohler, Susanna

    2016-11-01

    What impact did X-rays from the first binary star systems have on the universe around them? A new study suggests this radiation may have played an important role during the reionization of our universe.Ionizing the UniverseDuring the period of reionization, the universe reverted from being neutral (as it was during recombination, the previous period)to once again being ionized plasma a state it has remained in since then. This transition, which occurred between 150 million and one billion years after the Big Bang (redshift of 6 z 20), was caused by the formation of the first objects energetic enough to reionize the universes neutral hydrogen.ROSAT image of the soft X-ray background throughout the universe. The different colors represent different energy bands: 0.25 keV (red), 0.75 keV (green), 1.5 keV (blue). [NASA/ROSAT Project]Understanding this time period in particular, determining what sources caused the reionization, and what the properties were of the gas strewn throughout the universe during this time is necessary for us to be able to correctly interpret cosmological observations.Conveniently, the universe has provided us with an interesting clue: the large-scale, diffuse X-ray background we observe all around us. What produced these X-rays, and what impact did this radiation have on the intergalactic medium long ago?The First BinariesA team of scientists led by Hao Xu (UC San Diego) has suggested that the very first generation of stars might be an important contributor to these X-rays.This hypothetical first generation, Population III stars, are thought to have formed before and during reionization from large clouds of gas containing virtually no metals. Studies suggest that a large fraction of Pop III stars formed in binaries and when those stars ended their lives as black holes, ensuing accretion from their companions could produceX-ray radiation.The evolution with redshift of the mean X-ray background intensities. Each curve represents a different

  18. Modeling background radiation in Southern Nevada.

    Science.gov (United States)

    Haber, Daniel A; Burnley, Pamela C; Adcock, Christopher T; Malchow, Russell L; Marsac, Kara E; Hausrath, Elisabeth M

    2017-05-01

    Aerial gamma ray surveys are an important tool for national security, scientific, and industrial interests in determining locations of both anthropogenic and natural sources of radioactivity. There is a relationship between radioactivity and geology and in the past this relationship has been used to predict geology from an aerial survey. The purpose of this project is to develop a method to predict the radiologic exposure rate of the geologic materials by creating a high resolution background model. The intention is for this method to be used in an emergency response scenario where the background radiation environment is unknown. Two study areas in Southern Nevada have been modeled using geologic data, images from the Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER), geochemical data, and pre-existing low resolution aerial surveys from the National Uranium Resource Evaluation (NURE) Survey. Using these data, geospatial areas that are homogenous in terms of K, U, and Th, referred to as background radiation units, are defined and the gamma ray exposure rate is predicted. The prediction is compared to data collected via detailed aerial survey by the Department of Energy's Remote Sensing Lab - Nellis, allowing for the refinement of the technique. By using geologic units to define radiation background units of exposed bedrock and ASTER visualizations to subdivide and define radiation background units within alluvium, successful models have been produced for Government Wash, north of Lake Mead, and for the western shore of Lake Mohave, east of Searchlight, NV. Copyright © 2017 The Authors. Published by Elsevier Ltd.. All rights reserved.

  19. The stimulated Breit–Wheeler process as a source of background e+ ...

    Indian Academy of Sciences (India)

    Passage of beamstrahlung photons through the bunch fields at the interaction point of the ILC determines background pair production. The number of background pairs per bunch crossing due to the Breit-Wheeler, Bethe-Heitler and Landau-Lifshitz processes is well-known. However, the Breit-Wheeler process also takes ...

  20. "Gaining Power through Education": Experiences of Honduran Students from High Poverty Backgrounds

    Science.gov (United States)

    Mather, Peter C.; Zempter, Christy; Ngumbi, Elizabeth; Nakama, Yuki; Manley, David; Cox, Haley

    2017-01-01

    This is a study of students from high-poverty backgrounds attending universities in Honduras. Based on a series of individual and focus group interviews, the researchers found students from high-poverty backgrounds face numerous practical challenges in persisting in higher education. Despite these challenges, participants succeeded due to a…

  1. Design Considerations for Large Mass Ultra-Low Background Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Aguayo Navarrete, Estanislao; Reid, Douglas J.; Fast, James E.; Orrell, John L.

    2011-07-01

    Summary The objective of this document is to present the designers of the next generation of large-mass, ultra-low background experiments with lessons learned and design strategies from previous experimental work. Design issues divided by topic into mechanical, thermal and electrical requirements are addressed. Large mass low-background experiments have been recognized by the scientific community as appropriate tools to aid in the refinement of the standard model. The design of these experiments is very costly and a rigorous engineering review is required for their success. The extreme conditions that the components of the experiment must withstand (heavy shielding, vacuum/pressure and temperature gradients), in combination with unprecedented noise levels, necessitate engineering guidance to support quality construction and safe operating conditions. Physical properties and analytical results of typical construction materials are presented. Design considerations for achieving ultra-low-noise data acquisition systems are addressed. Five large-mass, low-background conceptual designs for the one-tonne scale germanium experiment are proposed and analyzed. The result is a series of recommendations for future experiments engineering and for the Majorana simulation task group to evaluate the different design approaches.

  2. Precise predictions for V+jets dark matter backgrounds

    Science.gov (United States)

    Lindert, J. M.; Pozzorini, S.; Boughezal, R.; Campbell, J. M.; Denner, A.; Dittmaier, S.; Gehrmann-De Ridder, A.; Gehrmann, T.; Glover, N.; Huss, A.; Kallweit, S.; Maierhöfer, P.; Mangano, M. L.; Morgan, T. A.; Mück, A.; Petriello, F.; Salam, G. P.; Schönherr, M.; Williams, C.

    2017-12-01

    High-energy jets recoiling against missing transverse energy (MET) are powerful probes of dark matter at the LHC. Searches based on large MET signatures require a precise control of the Z(ν {\\bar{ν }})+ jet background in the signal region. This can be achieved by taking accurate data in control regions dominated by Z(ℓ ^+ℓ ^-)+ jet, W(ℓ ν )+ jet and γ + jet production, and extrapolating to the Z(ν {\\bar{ν }})+ jet background by means of precise theoretical predictions. In this context, recent advances in perturbative calculations open the door to significant sensitivity improvements in dark matter searches. In this spirit, we present a combination of state-of-the-art calculations for all relevant V+ jets processes, including throughout NNLO QCD corrections and NLO electroweak corrections supplemented by Sudakov logarithms at two loops. Predictions at parton level are provided together with detailed recommendations for their usage in experimental analyses based on the reweighting of Monte Carlo samples. Particular attention is devoted to the estimate of theoretical uncertainties in the framework of dark matter searches, where subtle aspects such as correlations across different V+ jet processes play a key role. The anticipated theoretical uncertainty in the Z(ν {\\bar{ν }})+ jet background is at the few percent level up to the TeV range.

  3. Suppression of probe background signals via B1 field inhomogeneity

    Energy Technology Data Exchange (ETDEWEB)

    Feng, Jian; Reimer, Jeffrey

    2011-01-27

    A new approach combining a long pulse with the DEPTH sequence (Cory and Ritchey, Journal of Magnetic Resonance, 1988) greatly improves the efficiency for suppressing probe background signals arising from spinning modules. By applying a long initial excitation pulse in the DEPTH sequence, instead of a {pi}/2 pulse, the inhomogeneous B{sub 1} fields outside the coil can dephase the background coherence in the nutation frame. The initial long pulse and the following two consecutive EXORCYCLE {pi} pulses function complementarily and prove most effective in removing background signals from both strong and weak B{sub 1} fields. Experimentally, the length of the long pulse can be optimized around odd multiples of the {pi}/2 pulse, depending on the individual probe design, to preserve signals inside the coil while minimizing those from probe hardware. This method extends the applicability of the DEPTH sequence to probes with small differences in B{sub 1} field strength between the inside and outside of the coil, and can readily combine with well-developed double resonance experiments for quantitative measurement. In general, spin systems with weak internal interactions are required to attain efficient and uniform excitation for powder samples, and the principles to determine the applicability are discussed qualitatively in terms of the relative strength of spin interactions, r.f. power and spinning rate.

  4. FINANCIAL BACKGROUND OF INFRASTRUCTURAL DEVELOPMENT OF RURAL MUNICIPALITIES IN HUNGARY

    Directory of Open Access Journals (Sweden)

    Eszter SZEMLICS

    2004-10-01

    Full Text Available Due to the under-fi nancing of infrastructural developments of municipalities, rural areas are not able to implement the necessary investments. The fi nancial background must be established from different resources. State subsidies must be completed by commercial bank loans, funds from tenders and subsidies from the EU. ELMIB Inc. accomplishes infrastructure investments through municipalities in whole Hungary. Data of 35 municipalities was investigated (with questionnaire-survey in three regions, where the company made investments. The paper analyses the differences between operational and developmental incomes and expenditures in the three regions in 2002 and 2003.

  5. FINGERPRINTS OF GALACTIC LOOP I ON THE COSMIC MICROWAVE BACKGROUND

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Hao [Niels Bohr Institute and Discovery Center, Copenhagen University, Blegdamsvej 17, DK-2100 Copenhagen Ø (Denmark); Mertsch, Philipp [Kavli Institute for Particle Astrophysics and Cosmology, 2575 Sand Hill Road, M/S 29, Menlo Park, CA 94025 (United States); Sarkar, Subir, E-mail: liuhao@nbi.dk [Rudolf Peierls Centre for Theoretical Physics, University of Oxford, 1 Keble Road, Oxford OX1 3NP (United Kingdom)

    2014-07-10

    We investigate possible imprints of galactic foreground structures such as the ''radio loops'' in the derived maps of the cosmic microwave background. Surprisingly, there is evidence for these not only at radio frequencies through their synchrotron radiation, but also at microwave frequencies where emission by dust dominates. This suggests the mechanism is magnetic dipole radiation from dust grains enriched by metallic iron or ferrimagnetic molecules. This new foreground we have identified is present at high galactic latitudes, and potentially dominates over the expected B-mode polarization signal due to primordial gravitational waves from inflation.

  6. Environmental contamination due to shale gas development.

    Science.gov (United States)

    Annevelink, M P J A; Meesters, J A J; Hendriks, A J

    2016-04-15

    Shale gas development potentially contaminates both air and water compartments. To assist in governmental decision-making on future explorations, we reviewed scattered information on activities, emissions and concentrations related to shale gas development. We compared concentrations from monitoring programmes to quality standards as a first indication of environmental risks. Emissions could not be estimated accurately because of incomparable and insufficient data. Air and water concentrations range widely. Poor wastewater treatment posed the highest risk with concentrations exceeding both Natural Background Values (NBVs) by a factor 1000-10,000 and Lowest Quality Standards (LQSs) by a factor 10-100. Concentrations of salts, metals, volatile organic compounds (VOCs) and hydrocarbons exceeded aquatic ecotoxicological water standards. Future research must focus on measuring aerial and aquatic emissions of toxic chemicals, generalisation of experimental setups and measurement technics and further human and ecological risk assessment. Copyright © 2016 Elsevier B.V. All rights reserved.

  7. Experimental macroevolution†

    Science.gov (United States)

    Bell, Graham

    2016-01-01

    The convergence of several disparate research programmes raises the possibility that the long-term evolutionary processes of innovation and radiation may become amenable to laboratory experimentation. Ancestors might be resurrected directly from naturally stored propagules or tissues, or indirectly from the expression of ancestral genes in contemporary genomes. New kinds of organisms might be evolved through artificial selection of major developmental genes. Adaptive radiation can be studied by mimicking major ecological transitions in the laboratory. All of these possibilities are subject to severe quantitative and qualitative limitations. In some cases, however, laboratory experiments may be capable of illuminating the processes responsible for the evolution of new kinds of organisms. PMID:26763705

  8. A calculation of confusion noise due to infrared cirrus

    Science.gov (United States)

    Gautier, T. N., III; Boulanger, Francois; Perault, M.; Puget, J. L.

    1992-01-01

    General expressions are developed for the statistical errors to be expected in photometric measurements due to confusion in a background of fluctuating surface brightness. Backgrounds actually observed in the far IR by the IRAS satellite are used to calculate tables of these error expressions for two simple measurement techniques. The confusion-noise-limited sensitivities for NASA's planned Space IR Telescope Facility and the ESA's IR Space Observatory are estimated at a wavelength of 100 microns from these tables.

  9. Global Warming and the Microwave Background

    Directory of Open Access Journals (Sweden)

    Robitaille P.-M.

    2009-04-01

    Full Text Available In the work, the importance of assigning the microwave background to the Earth is ad- dressed while emphasizing the consequences for global climate change. Climate mod- els can only produce meaningful forecasts when they consider the real magnitude of all radiative processes. The oceans and continents both contribute to terrestrial emis- sions. However, the extent of oceanic radiation, particularly in the microwave region, raises concerns. This is not only since the globe is covered with water, but because the oceans themselves are likely to be weaker emitters than currently believed. Should the microwave background truly be generated by the oceans of the Earth, our planet would be a much less efficient emitter of radiation in this region of the electromagnetic spectrum. Furthermore, the oceans would appear unable to increase their emissions in the microwave in response to temperature elevation, as predicted by Stefan’s law. The results are significant relative to the modeling of global warming.

  10. [Acoustic analysis in different background of hearing].

    Science.gov (United States)

    Liu, Yun; Zhang, Daoxing; Liu, Yongxiang

    2003-08-01

    To find out the changes of voice in different noisy background by computer acoustic analysis. Twenty-five young people who got normal hearing level and normal vocal cords were selected. They were tested after trained. Sustained /a/,/i/ and sentences were recorded in the three different background: quite, white band noise and speech noise. The software of MDVP was used. Testing parameters included: F0, Jitter, Shimmer, APQ, PPQ, HNR. Fundamental frequencies of noisy groups are significantly higher in male-/a/, female-/a/ and female-/i/ groups. The perturbations are not significantly different among them. The HNR is negatively relative with F0. Normal hearing persons increase their fundamental frequencies in the noisy surroundings.

  11. Background reduction of a spherical gaseous detector

    Energy Technology Data Exchange (ETDEWEB)

    Fard, Ali Dastgheibi [Laboratoire Souterrain de Modane, France ali.dastgheibi-fard@lsm.in2p3.fr (France); Loaiza, Pia; Piquemal, Fabrice [Laboratoire Souterrain de Modane (France); Giomataris, Ioannis; Gray, David; Gros, Michel; Magnier, Patrick; Navick, Xavier-François [CEA Saclay - IRFU/SEDI - 91191 Gif sur Yvette (France); Savvidis, Ilias [Aristotle University of Thessaloniki (Greece)

    2015-08-17

    The Spherical gaseous detector (or Spherical Proportional Counter, SPC) is a novel type of detector. It consists of a large spherical volume filled with gas, using a single detection readout channel. The detector allows 100 % detection efficiency. SEDINE is a low background version of SPC installed at the Laboratoire Souterrain de Modane (LSM) underground laboratory (4800 m.w.e) looking for rare events at very low energy threshold, below 100 eV. This work presents the details on the chemical cleaning to reduce internal {sup 210}Pb surface contamination on the copper vessel and the external radon reduction achieved via circulation of pure air inside anti-radon tent. It will be also show the radon measurement of pure gases (Ar, N, Ne, etc) which are used in the underground laboratory for the low background experiments.

  12. A Detector for Cosmic Microwave Background Polarimetry

    Science.gov (United States)

    Wollack, E.; Cao, N.; Chuss, D.; Hsieh, W.-T.; Moseley, S. Harvey; Stevenson, T.; U-yen, K.

    2008-01-01

    We present preliminary design and development work on polarized detectors intended to enable Cosmic Microwave Background polarization measurements that will probe the first moments of the universe. The ultimate measurement will be challenging, requiring background-limited detectors and good control of systematic errors. Toward this end, we are integrating the beam control of HE-11 feedhorns with the sensitivity of transition-edge sensors. The coupling between these two devices is achieved via waveguide probe antennas and superconducting microstrip lines. This implementation allows band-pass filters to be incorporated on the detector chip. We believe that a large collection of single-mode polarized detectors will eventually be required for the reliable detection of the weak polarized signature that is expected to result from gravitational waves produced by cosmic inflation. This focal plane prototype is an important step along the path to this detection, resulting in a capability that will enable various future high performance instrument concepts.

  13. Background paper on Technology Roadmaps (TRMs)

    Energy Technology Data Exchange (ETDEWEB)

    More, E.; Phaal, R. [Institute for Manufacturing IfM, Department of Engineering, University of Cambridge, Cambridge (United Kingdom); Londo, H.M.; Wurtenberger, L.; Cameron, L.R. [ECN Policy Studies, Amsterdam (Netherlands)

    2013-04-15

    This background paper reports on the use of technology roadmaps (TRMs) related to climate change mitigation and adaptation technologies. The study is motivated by the UNFCCC Conference of the Parties (CoP) request to the Technology Executive Committee (TEC) to catalyse the development and use of TRMs as facilitative tools for action on mitigation and adaptation. Having originated in industry, TRMs are now used extensively in policy settings too, however their widespread use across sectors and by different stakeholders has resulted in a lack of understanding of their real value to help catalyse cooperation towards technological solutions to the problems presented by climate change. Consequently this background paper presents (1) an overview of different TRM methods, (2) an initial analysis of gaps and barriers in existing TRMs, and (3) a review of current TRM good practices.

  14. Spontaneous Radiation Background Calculation for LCLS

    CERN Document Server

    Reiche, Sven

    2004-01-01

    The intensity of undulator radiation, not amplified by the FEL interaction, can be larger than the maximum FEL signal in the case of an X-ray FEL. In the commissioning of a SASE FEL it is essential to extract an amplified signal early to diagnose eventual misalignment of undulator modules or errors in the undulator field strength. We developed a numerical code to calculate the radiation pattern at any position behind a multi-segmented undulator with arbitrary spacing and field profiles. The output can be run through numerical spatial and frequency filters to model the radiation beam transport and diagnostic. In this presentation we estimate the expected background signal for the FEL diagnostic and at what point along the undulator the FEL signal can be separated from the background. We also discusses how much information on the undulator field and alignment can be obtained from the incoherent radiation signal itself.

  15. Social background, bullying, and physical inactivity

    DEFF Research Database (Denmark)

    Henriksen, P W; Rayce, S B; Melkevik, O

    2016-01-01

    More children from lower social backgrounds are physically inactive than those from higher ones. We studied whether bullying was a mediating factor between lower social background and physical inactivity. We also examined the combined effect of low social class and exposure to bullying on physical...... inactivity among students from lower social classes and for students exposed to bullying. There was a combined effect of low social class and bullying on physical inactivity....... leaves 4.0% in the category physically inactive. The sex and age-adjusted OR (95% CI) for physical inactivity was 2.10 (1.39-3.18) among students with low social class and unclassifiable 3.53 (2.26-5.53). Exposure to bullying was associated with physical inactivity, sex and age-adjusted OR = 2.39 (1...

  16. Foreign Energy Company Competitiveness: Background information

    Energy Technology Data Exchange (ETDEWEB)

    Weimar, M.R.; Freund, K.A.; Roop, J.M.

    1994-10-01

    This report provides background information to the report Energy Company Competitiveness: Little to Do With Subsidies (DOE 1994). The main body of this publication consists of data uncovered during the course of research on this DOE report. This data pertains to major government energy policies in each country studied. This report also provides a summary of the DOE report. In October 1993, the Office of Energy Intelligence, US Department of Energy (formerly the Office of Foreign Intelligence), requested that Pacific Northwest Laboratory prepare a report addressing policies and actions used by foreign governments to enhance the competitiveness of their energy firms. Pacific Northwest Laboratory prepared the report Energy Company Competitiveness Little to Do With Subsidies (DOE 1994), which provided the analysis requested by DOE. An appendix was also prepared, which provided extensive background documentation to the analysis. Because of the length of the appendix, Pacific Northwest Laboratory decided to publish this information separately, as contained in this report.

  17. Family Background and Educational Success in Denmark

    DEFF Research Database (Denmark)

    D. Munk, Martin; McIntoch, James

    This research examines the role of family background variables in the determination of educational attainment in Denmark. A categorical representation of the highest level of education attained is the dependent variable. It is analyzed by procedures which take account of the presence of unobserva......This research examines the role of family background variables in the determination of educational attainment in Denmark. A categorical representation of the highest level of education attained is the dependent variable. It is analyzed by procedures which take account of the presence...... procedures are in the spirit of the work of Cameron and Heckman (1998), but are more general. Econometric issues and the results of what other Scandinavian researchers in this area have found are also discussed in section 4....

  18. Background matching by means of dorsal color change in treefrog populations (Hyla japonica).

    Science.gov (United States)

    Choi, Noori; Jang, Yikweon

    2014-02-01

    Treefrogs change dorsal coloration to match background colors, presumably for predator avoidance. Dorsal coloration in treefrogs results from rearrangement of pigment granules in dermal chromatophores. This physiological basis for color change suggests that brightness and chroma are the color components that may change in response to background color. However, results of experiments are conflicting in that there is no consensus as to which color component is critical for color change in treefrogs. We tested predictions of the physiological model for color change in treefrogs by investigating dorsal color change under five background colors in three different populations of the treefrog Hyla japonica. Differences in color components between background colors and frogs were used as a measure of background matching. Throughout a 1-week experimental period, brightness and chroma differences decreased monotonically, while hue difference remained constant for all background colors. Chroma differences were smaller with the natural colors such as green and brown than with achromatic colors. Moreover, variation in color change among frogs from three localities that differed in land cover suggested that chroma change capacity may be sensitive to environmental conditions. Under the white background color, however, decreasing brightness difference seemed to be crucial to background matching. Furthermore, chroma difference and brightness difference did not decrease indefinitely, suggesting a trade-off between chroma difference and brightness difference under the white background. Thus, background matching may generally occur by decreasing chroma difference under most background colors in H. japonica, but brightness matching may be important under the white color. © 2013 Wiley Periodicals, Inc.

  19. Background Model for the Majorana Demonstrator

    Energy Technology Data Exchange (ETDEWEB)

    Cuesta, C.; Abgrall, N.; Aguayo, Estanislao; Avignone, Frank T.; Barabash, Alexander S.; Bertrand, F.; Boswell, M.; Brudanin, V.; Busch, Matthew; Byram, D.; Caldwell, A. S.; Chan, Yuen-Dat; Christofferson, Cabot-Ann; Combs, Dustin C.; Detwiler, Jason A.; Doe, Peter J.; Efremenko, Yuri; Egorov, Viatcheslav; Ejiri, H.; Elliott, S. R.; Fast, James E.; Finnerty, P.; Fraenkle, Florian; Galindo-Uribarri, A.; Giovanetti, G. K.; Goett, J.; Green, M. P.; Gruszko, J.; Guiseppe, Vincente; Gusev, K.; Hallin, A. L.; Hazama, R.; Hegai, A.; Henning, Reyco; Hoppe, Eric W.; Howard, Stanley; Howe, M. A.; Keeter, K.; Kidd, M. F.; Kochetov, Oleg; Konovalov, S.; Kouzes, Richard T.; Laferriere, Brian D.; Leon, Jonathan D.; Leviner, L.; Loach, J. C.; MacMullin, J.; MacMullin, S.; Martin, R. D.; Meijer, S. J.; Mertens, S.; Nomachi, Masaharu; Orrell, John L.; O' Shaughnessy, C.; Overman, Nicole R.; Phillips, D.; Poon, Alan; Pushkin, K.; Radford, D. C.; Rager, J.; Rielage, Keith; Robertson, R. G. H.; Romero-Romero, E.; Ronquest, M. C.; Schubert, Alexis G.; Shanks, B.; Shima, T.; Shirchenko, M.; Snavely, Kyle J.; Snyder, N.; Suriano, Anne-Marie; Thompson, J.; Timkin, V.; Tornow, Werner; Trimble, J. E.; Varner, R. L.; Vasilyev, Sergey; Vetter, Kai; Vorren, Kris R.; White, Brandon R.; Wilkerson, J. F.; Wiseman, C.; Xu, W.; Yakushev, E.; Young, A.; Yu, Chang-Hong; Yumatov, Vladimir

    2015-06-01

    The Majorana Collaboration is constructing a prototype system containing 40 kg of HPGe detectors to demonstrate the feasibility and potential of a future tonne-scale experiment to search for neutrinoless double-beta (0v BB) decay in 76Ge. In view of the requirement that the next generation of tonne-scale Ge-based 0vBB-decay experiment be capable of probing the neutrino mass scale in the inverted-hierarchy region, a major goal of theMajorana Demonstrator is to demonstrate a path forward to achieving a background rate at or below 1 cnt/(ROI-t-y) in the 4 keV region of interest around the Q-value at 2039 keV. This goal is pursued through a combination of a significant reduction of radioactive impurities in construction materials with analytical methods for background rejection, for example using powerful pulse shape analysis techniques profiting from the p-type point contact HPGe detectors technology. The effectiveness of these methods is assessed using Geant4 simulations of the different background components whose purity levels are constrained from radioassay measurements.

  20. Cosmological origin of anomalous radio background

    Energy Technology Data Exchange (ETDEWEB)

    Cline, James M. [Department of Physics, McGill University, 3600 Rue University, Montréal, Québec, H3A 2T8 Canada (Canada); Vincent, Aaron C., E-mail: jcline@physics.mcgill.ca, E-mail: vincent@ific.uv.es [Instituto de Física Corpuscular, Universitat de València - CSIC, 46071, Valencia (Spain)

    2013-02-01

    The ARCADE 2 collaboration has reported a significant excess in the isotropic radio background, whose homogeneity cannot be reconciled with clustered sources. This suggests a cosmological origin prior to structure formation. We investigate several potential mechanisms and show that injection of relativistic electrons through late decays of a metastable particle can give rise to the observed excess radio spectrum through synchrotron emission. However, constraints from the cosmic microwave background (CMB) anisotropy, on injection of charged particles and on the primordial magnetic field, present a challenge. The simplest scenario is with a ∼>9 GeV particle decaying into e{sup +}e{sup −} at a redshift of z ∼ 5, in a magnetic field of ∼ 5μG, which exceeds the CMB B-field constraints, unless the field was generated after decoupling. Decays into exotic millicharged particles can alleviate this tension, if they emit synchroton radiation in conjunction with a sufficiently large background magnetic field of a dark U(1)' gauge field.

  1. Holographic Hall conductivities from dyonic backgrounds

    Energy Technology Data Exchange (ETDEWEB)

    Lindgren, Jonathan [Theoretische Natuurkunde, Vrije Universiteit Brussel and International Solvay Institutes,Pleinlaan 2, B-1050 Brussels (Belgium); Physique Théorique et Mathématique, Université Libre de Bruxelles,Campus Plaine C.P. 231, B-1050 Bruxelles (Belgium); Papadimitriou, Ioannis [SISSA and INFN - Sezione di Trieste,Via Bonomea 265, I 34136 Trieste (Italy); Taliotis, Anastasios; Vanhoof, Joris [Theoretische Natuurkunde, Vrije Universiteit Brussel and International Solvay Institutes,Pleinlaan 2, B-1050 Brussels (Belgium)

    2015-07-20

    We develop a general framework for computing the holographic 2-point functions and the corresponding conductivities in asymptotically locally AdS backgrounds with an electric charge density, a constant magentic field, and possibly non-trivial scalar profiles, for a broad class of Einstein-Maxwell-Axion-Dilaton theories, including certain Chern-Simons terms. Holographic renormalization is carried out for any theory in this class and the computation of the renormalized AC conductivities at zero spatial momentum is reduced to solving a single decoupled first order Riccati equation. Moreover, we develop a first order fake supergravity formulalism for dyonic renormalization group flows in four dimensions, allowing us to construct analytically infinite families of such backgrounds by specifying a superpotential at will. These RG flows interpolate between AdS{sub 4} in the UV and a hyperscaling violating Lifshitz geometry in the IR with exponents 1background, both in the context of AdS/CMT and AdS/QCD.

  2. Radon background study in Super-Kamiokande

    Science.gov (United States)

    Nakano, Yuuki; Super-Kamiokande Collaboration

    2017-09-01

    Super-Kamiokande (SK), a 50 kton water Cherenkov detector in Japan, observes 8B solar neutrinos with neutrino-electron elastic scattering. SK searches for distortions of the solar neutrino energy spectrum caused by the edge of the MSW resonance in the core of the Sun. The installation of new front-end electronics in 2008 marks the beginning of the 4th phase of SK (SK-IV). With the improvement of the water circulation system, calibration methods, reduction cuts, this phase achieved the lowest energy threshold thus far (3.5 MeV kinetic energy). To improve the sensitivity to the MSW effect, it is required to achieve lower energy threshold. For this purpose, understanding the origin of background events and reducing them are important. Currently, the main background is known as a beta decay of 214Bi in a Radon decay chain. So far, SK collaboration has developed several techniques for studying Radon contamination in the SK water. In this proceedings, a measurement system which can measure Radon concentration in the SK water with the accuracy of 0.1 mBq/m3 level is presented. In addition, an evaluation of Radon background events in SK injecting Radon rich water into the SK tank, as well as future prospects are also presented.

  3. Cosmic Infrared Background Fluctuations and Zodiacal Light

    Science.gov (United States)

    Arendt, Richard G.; Kashlinsky, A.; Moseley, S. H.; Mather, J.

    2017-01-01

    We performed a specific observational test to measure the effect that the zodiacal light can have on measurements of the spatial fluctuations of the near-IR (near-infrared)background. Previous estimates of possible fluctuations caused by zodiacal light have often been extrapolated from observations of the thermal emission at longer wavelengths and low angular resolution or from IRAC (Infrared Array Camera) observations of high-latitude fields where zodiacal light is faint and not strongly varying with time. The new observations analyzed here target the COSMOS (Cosmic Evolution Survey) field at low ecliptic latitude where the zodiacal light intensity varies by factors of approximately 2 over the range of solar elongations at which the field can be observed. We find that the white-noise component of the spatial power spectrum of the background is correlated with the modeled zodiacal light intensity. Roughly half of the measured white noise is correlated with the zodiacal light, but a more detailed interpretation of the white noise is hampered by systematic uncertainties that are evident in the zodiacal light model. At large angular scales (greater than or approximately equal to 100 arcseconds) where excess power above the white noise is observed, we find no correlation of the power with the modeled intensity of the zodiacal light. This test clearly indicates that the large-scale power in the infrared background is not being caused by the zodiacal light.

  4. Experimental macroevolution.

    Science.gov (United States)

    Bell, Graham

    2016-01-13

    The convergence of several disparate research programmes raises the possibility that the long-term evolutionary processes of innovation and radiation may become amenable to laboratory experimentation. Ancestors might be resurrected directly from naturally stored propagules or tissues, or indirectly from the expression of ancestral genes in contemporary genomes. New kinds of organisms might be evolved through artificial selection of major developmental genes. Adaptive radiation can be studied by mimicking major ecological transitions in the laboratory. All of these possibilities are subject to severe quantitative and qualitative limitations. In some cases, however, laboratory experiments may be capable of illuminating the processes responsible for the evolution of new kinds of organisms. © 2016 The Author(s).

  5. Incremental Sampling Methodology: Applications for Background Screening Assessments.

    Science.gov (United States)

    Pooler, Penelope S; Goodrum, Philip E; Crumbling, Deana; Stuchal, Leah D; Roberts, Stephen M

    2018-01-01

    This article presents the findings from a numerical simulation study that was conducted to evaluate the performance of alternative statistical analysis methods for background screening assessments when data sets are generated with incremental sampling methods (ISMs). A wide range of background and site conditions are represented in order to test different ISM sampling designs. Both hypothesis tests and upper tolerance limit (UTL) screening methods were implemented following U.S. Environmental Protection Agency (USEPA) guidance for specifying error rates. The simulations show that hypothesis testing using two-sample t-tests can meet standard performance criteria under a wide range of conditions, even with relatively small sample sizes. Key factors that affect the performance include unequal population variances and small absolute differences in population means. UTL methods are generally not recommended due to conceptual limitations in the technique when applied to ISM data sets from single decision units and due to insufficient power given standard statistical sample sizes from ISM. © 2017 Society for Risk Analysis.

  6. Use of Vocalic Cues to Consonant Voicing and Native Language Background: The Influence of Experimental Design

    National Research Council Canada - National Science Library

    Crowther, Court S; Mann, Virginia

    1994-01-01

    For native speakers of English and several other languages, preceding vocalic duration and F1 offset frequency are two of the cues that convey the stop consonant voicing distinction in word-final position...

  7. DIFFUSION BACKGROUND MODEL FOR MOVING OBJECTS DETECTION

    Directory of Open Access Journals (Sweden)

    B. V. Vishnyakov

    2015-05-01

    Full Text Available In this paper, we propose a new approach for moving objects detection in video surveillance systems. It is based on construction of the regression diffusion maps for the image sequence. This approach is completely different from the state of the art approaches. We show that the motion analysis method, based on diffusion maps, allows objects that move with different speed or even stop for a short while to be uniformly detected. We show that proposed model is comparable to the most popular modern background models. We also show several ways of speeding up diffusion maps algorithm itself.

  8. Background of the Degree in Public Accounting

    Directory of Open Access Journals (Sweden)

    José G. Vargas-Hernández

    2012-08-01

    Full Text Available This paper aims to review public accountant education in terms of the interrelated subjects as well as its background. The results of this education development project improve the formation of the accountant public education because of its linkage between teachers and students in the research process and the design of new teaching strategies that contribute to solving real problems and facilitate the social projection. The academic administration is characterized by processes that arise and is generated within the same individuals, focused on the construction and reconstruction of knowledge, proper training and formation of builders of their own processes.

  9. Natural Radiation Background in Metropolitan Taipei

    OpenAIRE

    PAO-SHAN, WENG; TIEH-CHI, CHU; CHlN-FANG, CHEN; Institute of Nuclear Science National Tsing Hua University; Radiation Laboratory, Taiwan Power Company

    1991-01-01

    A high-pressure ionization chamber was used to measure the natural background radiation in metropolitan Taipei, Taiwan, R. O. C. during a period in 1987-1988. The average exposure rate was 27.55×10^ C kg^ h^ including cosmic radiation, but the radon contribution was excluded. Scintillation survey meter, gamma-ray spectroscopy for soil samples, in-situ measurement with a NaI(Tl) detector coupled to a portable multichannel analyzer, instrumental neutron activation analysis of rock samples, and ...

  10. Beam-gas background calculation for DEAR

    Energy Technology Data Exchange (ETDEWEB)

    Guiducci, S. [INFN, Frascati (Italy). Laboratori Nazionali di Frascati; Iliescu, M. A. [IFIN-HH, Bucharest (Romania)

    1997-01-01

    The present paper describes the results obtained from a Monte Carlo simulation of the particles lost in the DAY-ONE Interaction Region (IR) of the DAFNE machine. Coulomb scattering on the nuclei of residual gas and beam-gas Bremsstrahlung, which are the main sources of background in the initial phase of machine operation, were considered. A ray-tracking program (TURTLE) was used to follow the trajectories of the particles in the rings and to evaluate the number of particles that hit the vacuum chamber in the interaction region.

  11. Background instrumental music and serial recall.

    Science.gov (United States)

    Nittono, H

    1997-06-01

    Although speech and vocal music are consistently shown to impair serial recall for visually presented items, instrumental music does not always produce a significant disruption. This study investigated the features of instrumental music that would modulate the disruption in serial recall. 24 students were presented sequences of nine digits and required to recall the digits in order of presentation. Instrumental music as played either forward or backward during the task. Forward music caused significantly more disruption than did silence, whereas the reversed music did not. Some higher-order factor may be at work in the effect of background music on serial recall.

  12. Hanford Site background: Part 1, Soil background for nonradioactive analytes. Revision 1, Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1993-04-01

    The determination of soil background is one of the most important activities supporting environmental restoration and waste management on the Hanford Site. Background compositions serve as the basis for identifying soil contamination, and also as a baseline in risk assessment processes used to determine soil cleanup and treatment levels. These uses of soil background require an understanding of the extent to which analytes of concern occur naturally in the soils. This report documents the results of sampling and analysis activities designed to characterize the composition of soil background at the Hanford Site, and to evaluate the feasibility for use as Sitewide background. The compositions of naturally occurring soils in the vadose Zone have been-determined for-nonradioactive inorganic and organic analytes and related physical properties. These results confirm that a Sitewide approach to the characterization of soil background is technically sound and is a viable alternative to the determination and use of numerous local or area backgrounds that yield inconsistent definitions of contamination. Sitewide soil background consists of several types of data and is appropriate for use in identifying contamination in all soils in the vadose zone on the Hanford Site. The natural concentrations of nearly every inorganic analyte extend to levels that exceed calculated health-based cleanup limits. The levels of most inorganic analytes, however, are well below these health-based limits. The highest measured background concentrations occur in three volumetrically minor soil types, the most important of which are topsoils adjacent to the Columbia River that are rich in organic carbon. No organic analyte levels above detection were found in any of the soil samples.

  13. Workshop Background and Summary of Webinars (IVIVE ...

    Science.gov (United States)

    Toxicokinetics (TK) provides a bridge between hazard and exposure by predicting tissue concentrations due to exposure. Higher throughput toxicokinetics (HTTK) appears to provide essential data to established context for in vitro bioactivity data obtained through high throughput screening. The National Toxicology Program has sponsored the workshop

  14. Low Background Phase of KamLAND

    Science.gov (United States)

    Keefer, Gregory

    2008-04-01

    The KamLAND collaboration operates a 1 kton liquid scintillation detector in the Kamioka mine in Japan. KamLAND's main scientific results are the precision measurement of the solar δm^2 utilizing reactor anti-neutrinos and first evidence for the observation of geologically produced anti-neutrinos. The KamLAND collaboration has been working toward upgrading the detector for a low background phase. During the spring of 2007, we performed the first phase of purification by circulating 1.3 ktons of KamLAND liquid scintillator through a newly developed distillation and purging system. The ultimate goal of purification is to allow for a direct measurement of the 862 keV, ^7Be neutrinos originating from the Sun. A description of the purification process, liquid scintillator quality control measures, and detector monitoring will be presented. The achieved background reduction after this first phase of purification and planned future work on KamLAND will be discussed.

  15. DNA sequencing using fluorescence background electroblotting membrane

    Science.gov (United States)

    Caldwell, K.D.; Chu, T.J.; Pitt, W.G.

    1992-05-12

    A method for the multiplex sequencing on DNA is disclosed which comprises the electroblotting or specific base terminated DNA fragments, which have been resolved by gel electrophoresis, onto the surface of a neutral non-aromatic polymeric microporous membrane exhibiting low background fluorescence which has been surface modified to contain amino groups. Polypropylene membranes are preferably and the introduction of amino groups is accomplished by subjecting the membrane to radio or microwave frequency plasma discharge in the presence of an aminating agent, preferably ammonia. The membrane, containing physically adsorbed DNA fragments on its surface after the electroblotting, is then treated with crosslinking means such as UV radiation or a glutaraldehyde spray to chemically bind the DNA fragments to the membrane through amino groups contained on the surface. The DNA fragments chemically bound to the membrane are subjected to hybridization probing with a tagged probe specific to the sequence of the DNA fragments. The tagging may be by either fluorophores or radioisotopes. The tagged probes hybridized to the target DNA fragments are detected and read by laser induced fluorescence detection or autoradiograms. The use of aminated low fluorescent background membranes allows the use of fluorescent detection and reading even when the available amount of DNA to be sequenced is small. The DNA bound to the membranes may be reprobed numerous times. No Drawings

  16. Alpha Background Discrimination in the MAJORANA DEMONSTRATOR

    Science.gov (United States)

    Gruszko, Julieta; The Majorana Collaboration

    2017-09-01

    The type="smallcap">Majorana Demonstrator (MJD) searches for neutrinoless double-beta decay of 76Ge using arrays of high-purity germanium detectors. If observed, this process would have implications for grand-unification and the predominance of matter over antimatter in the universe. A problematic background in such large granular detector arrays is posed by alpha particles. In MJD, potential background events that are consistent with energy-degraded alphas originating on the passivated detector surface have been observed. We have studied these events by scanning the passivated surface of a P-type point contact detector like those used in MJD with a collimated alpha source. We observe that surface alpha events exhibit high charge-trapping, with a significant fraction of the trapped charge being re-released slowly. This leads to both a reduced prompt signal and a measurable change in slope of the tail of a recorded pulse. In this contribution we discuss the characteristics of these events and the filter developed to identify the occurrence of this delayed charge recovery, allowing for the efficient rejection of passivated surface alpha events while retaining 99.8% of bulk events. We also discuss the impact of this filter on the sensitivity of MJD. This material is based upon work supported by the U.S. DOE, Office of Science, Office of Nuclear Phys., the Particle Astrophys. and Nuclear Phys. Programs of the NSF, and SURF. Additional support from the NSFGRFP under Grant No. 1256082.

  17. Detection prospects for the Cosmic Neutrino Background using laser interferometers

    Science.gov (United States)

    Domcke, Valerie; Spinrath, Martin

    2017-06-01

    The cosmic neutrino background is a key prediction of Big Bang cosmology which has not been observed yet. The movement of the earth through this neutrino bath creates a force on a pendulum, as if it were exposed to a cosmic wind. We revise here estimates for the resulting pendulum acceleration and compare it to the theoretical sensitivity of an experimental setup where the pendulum position is measured using current laser interferometer technology as employed in gravitational wave detectors. We discuss how a significant improvement of this setup can be envisaged in a micro gravity environment. The proposed setup could also function as a dark matter detector in the sub-MeV range, which currently eludes direct detection constraints.

  18. Experimental music for experimental physics

    CERN Multimedia

    Rosaria Marraffino

    2014-01-01

    Using the sonification technique, physicist and composer Domenico Vicinanza paid homage to CERN at its 60th anniversary ceremony. After months of hard work, he turned the CERN Convention and LHC data into music.   Click here to download the full score of the "LHChamber music". Every birthday deserves gifts and CERN’s 60th anniversary was no exception. Two gifts were very special, thanks to the hard work of Domenico Vicinanza, a physicist and composer. He created two experimental pieces by applying the sonification technique to the CERN Convention and to data recorded by the four LHC detectors during Run 1. “This technique allows us to ‘hear’ data using an algorithm that translates numbers or letters into notes. It keeps the same information enclosed in a graph or a document, but has a more aesthetic exposition,” explains Domenico Vicinanza. “The result is meant to be a metaphor for scientific cooperation, in which d...

  19. Low-background germanium radioassay for the MAJORANA Collaboration

    Science.gov (United States)

    Trimble, James E., Jr.

    The focus of the MAJORANA COLLABORATION is the search for nuclear neutrinoless double beta decay. If discovered, this process would prove that the neutrino is its own anti-particle, or a M AJORANA particle. Being constructed at the Sanford Underground Research Facility, the MAJORANA DEMONSTRATOR aims to show that a background rate of 3 counts per region of interest (ROI) per tonne per year in the 4 keV ROI surrounding the 2039-keV Q-value energy of 76Ge is achievable and to demonstrate the technological feasibility of building a tonne-scale Ge-based experiment. Because of the rare nature of this process, detectors in the system must be isolated from ionizing radiation backgrounds as much as possible. This involved building the system with materials containing very low levels of naturally- occurring and anthropogenic radioactive isotopes at a deep underground site. In order to measure the levels of radioactive contamination in some components, the Majorana Demonstrator uses a low background counting facility managed by the Experimental Nuclear and Astroparticle Physics (ENAP) group at UNC. The UNC low background counting (LBC) facility is located at the Kimballton Underground Research Facility (KURF) located in Ripplemead, VA. The facility was used for a neutron activation analysis of samples of polytetrafluoroethylene (PTFE) and fluorinated ethylene propylene (FEP) tubing intended for use in the Demonstrator. Calculated initial activity limits (90% C.L.) of 238U and 232Th in the 0.002-in PTFE samples were 7.6 ppt and 5.1 ppt, respectively. The same limits in the FEP tubing sample were 150 ppt and 45 ppt, respectively. The UNC LBC was also used to gamma-assay a modified stainless steel flange to be used as a vacuum feedthrough. Trace activities of both 238U and 232Th were found in the sample, but all were orders of magnitude below the acceptable threshold for the Majorana experiment. Also discussed is a proposed next generation ultra-low background system designed

  20. Beamstop-based low-background ptychography to image weakly scattering objects

    DEFF Research Database (Denmark)

    Reinhardt, Juliane; Hoppe, Robert; Hofmann, Georg

    2017-01-01

    of the complementary information contained in the two scans. We experimentally demonstrate the potential of this scheme for hard X-ray ptychography by imaging a weakly scattering object composed of catalytic nanoparticles and provide the analysis of the signal-to-background ratio in the diffraction patterns......., which improve the experimental setup in terms of background reduction or better coverage of high dynamic range in the diffraction patterns. Here, we discuss an alternative approach: we combine two ptychographic scans with and without beamstop and reconstruct them simultaneously taking advantage...

  1. Background Oriented Schlieren Implementation in a Jet-Surface Interaction Test

    Science.gov (United States)

    Clem, Michelle M.; Brown, Clifford A.; Fagan, Amy

    2013-01-01

    Many current and future aircraft designs rely on the wing or other aircraft surfaces to shield the engine noise from observers on the ground. However the available data regarding how a planar surface interacts with a jet to shield and/or enhance the jet noise are currently limited. Therefore, the Jet-Surface Interaction Tests supported by NASA's Fundamental Aeronautics Program's Fixed Wing Project were undertaken to supply experimental data covering a wide range of surface geometries and positions interacting with high-speed jet flows in order to support the development of noise prediction methods. Phase 1 of the Test was conducted in the Aero-Acoustic Propulsion Laboratory at NASA Glenn Research Center and consisted of validating noise prediction schemes for a round nozzle interacting with a planar surface. Phased array data and far-field acoustic data were collected for both the shielded and reflected sides of the surface. Phase 1 results showed that the broadband shock noise was greatly reduced by the surface when the jet was operated at the over-expanded condition, however, it was unclear whether this reduction was due a change in the shock cell structure by the surface. In the present study, Background Oriented Schlieren is implemented in Phase 2 of the Jet-Surface Interaction Tests to investigate whether the planar surface interacts with the high-speed jet ow to change the shock cell structure. Background Oriented Schlieren data are acquired for under-expanded, ideally-expanded, and over-expanded ow regimes for multiple axial and radial positions of the surface at three different plate lengths. These data are analyzed with far-field noise measurements to relate the shock cell structure to the broadband shock noise produced by a jet near a surface.

  2. Can muon-induced backgrounds explain the DAMA data?

    Science.gov (United States)

    Klinger, Joel; Kudryavtsev, Vitaly A.

    2016-05-01

    We present an accurate simulation of the muon-induced background in the DAMA/LIBRA experiment. Muon sampling underground has been performed using the MUSIC/MUSUN codes and subsequent interactions in the rock around the DAMA/LIBRA detector cavern and the experimental setup including shielding, have been simulated with GEANT4.9.6. In total we simulate the equivalent of 20 years of muon data. We have calculated the total muon-induced neutron flux in the DAMA/LIBRA detector cavern as Φμ n = 1.0 × 10-9 cm-2s-1, which is consistent with other simulations. After selecting events which satisfy the DAMA/LIBRA signal criteria, our simulation predicts 3.49 × 10-5 cpd/kg/keV which accounts for less than 0.3% of the DAMA/LIBRA modulation amplitude. We conclude from our work that muon-induced backgrounds are unable to contribute to the observed signal modulation.

  3. Water, Hydrogen Bonding and the Microwave Background

    Directory of Open Access Journals (Sweden)

    Robitaille P.-M.

    2009-04-01

    Full Text Available n this work, the properties of the water are briefly revisited. Though liquid water has a fleeting structure, it displays an astonishingly stable network of hydrogen bonds. Thus, even as a liquid, water possesses a local lattice with short range order. The presence of hydroxyl (O-H and hydrogen (H....OH2 bonds within water, indicate that it can simultaneously maintain two separate energy systems. These can be viewed as two very different temperatures. The analysis presented uses results from vibrational spec- troscopy, extracting the force constant for the hydrogen bonded dimer. By idealizing this species as a simple diatomic structure, it is shown that hydrogen bonds within wa- ter should be able to produce thermal spectra in the far infrared and microwave regions of the electromagnetic spectrum. This simple analysis reveals that the oceans have a physical mechanism at their disposal, which is capable of generating the microwave background.

  4. On the cosmic microwave background radiation

    Directory of Open Access Journals (Sweden)

    José Maria Filardo Bassalo

    2017-12-01

    Full Text Available In this article we will try to give a pale idea to the reader of what could be the Cosmic Microwave Background (RCFM that, according to the traditional Big Bang model, was generated by a primordial explosion. With this purpose we find it very important to present a brief historical summary of how the Microcosm, based on the Standard Model of Elementary Particle Physics (MPPE, and the Macrocosm, based on the Standard Big Bang Model (MPBB, have evolved over time. In addition, in the final part of the article we will analyze the two physical processes presented in the literature that seek to explain the RCFM: Bariogenesis and Plasma Quark-Gluon.

  5. Social Class, Family Background and Intergenerational Mobility

    DEFF Research Database (Denmark)

    D. Munk, Martin; McIntosh, James

    This research examines the various approaches taken by economists and sociologists for analyzing intergenerational mobility. Social mobility models based on social classes arising from an occupational classification scheme are analyzed. A test for the statistical validity of classification schemes...... is proposed and tested using Danish sample survey data that was first collected in 1976 and augmented in 2000. This is referred to as a homogeneity test and is a likelihood ratio test of a set of linear restrictions which define social classes. For Denmark it is shown that this test fails for an Erikson......-Goldthorpe classification system, raising doubts about the statistical validity of occupational classification systems in general. We also estimate regression models of occupational earnings, household earnings, and educational attainment using family background variables as covariates controlling for unobservables...

  6. Multiphoton amplitude in a constant background field

    Science.gov (United States)

    Ahmad, Aftab; Ahmadiniaz, Naser; Corradini, Olindo; Kim, Sang Pyo; Schubert, Christian

    2018-01-01

    In this contribution, we present our recent compact master formulas for the multiphoton amplitudes of a scalar propagator in a constant background field using the worldline fomulation of quantum field theory. The constant field has been included nonperturbatively, which is crucial for strong external fields. A possible application is the scattering of photons by electrons in a strong magnetic field, a process that has been a subject of great interest since the discovery of astrophysical objects like radio pulsars, which provide evidence that magnetic fields of the order of 1012G are present in nature. The presence of a strong external field leads to a strong deviation from the classical scattering amplitudes. We explicitly work out the Compton scattering amplitude in a magnetic field, which is a process of potential relevance for astrophysics. Our final result is compact and suitable for numerical integration.

  7. Characterizing superconducting filters using residual microwave background

    Science.gov (United States)

    Lehtinen, J. S.; Mykkänen, E.; Kemppinen, A.; Lotkhov, S. V.; Golubev, D.; Manninen, A. J.

    2017-05-01

    A normal metal-superconductor hybrid single-electron trap with tunable barrier is utilized as a tool for spectrum analysis at the extremely low signal levels, using only well filtered cryogenic microwave background as a photon source in the frequency range from about 50 to 210 GHz. We probe millimeter wave propagation in two superconducting systems: a Josephson junction array around its plasma frequency, and a superconducting titanium film in the limit when the photon energies are larger than the superconducting energy gap. This regime is relevant for improving the performance of cryogenic quantum devices but is hard to access with conventional techniques. We show that relatively simple models can be used to describe the essential properties of the studied components.

  8. Cosmic Microwave Background Polarization and Inflation

    Science.gov (United States)

    Chuss, David T.

    2011-01-01

    Measurements of the cosmic microwave background (CMB) offer a means to explore the universe at a very early epoch. Specifically, if the universe went through a brief period of exponential expansion called inflation as current data suggest, gravitational waves from this period would polarize the CMB in a specific pattern. At GSFC, we are currently working towards two experiments that work in concert to measure this polarization pattern in search of evidence for inflation. The Cosmology Large Angular Scale Surveyor (CLASS) will measure the polarization at frequencies between 40 and 150 GHz from the Atacama Desert in Chile. The Primordial Inflation Polarization Explorer (PIPER) is a balloon-borne experiment that will make similar measurements at frequencies between 200 and 600 GHz.

  9. Insights into the background of autonomic medicine.

    Science.gov (United States)

    Laranjo, Sérgio; Geraldes, Vera; Oliveira, Mário; Rocha, Isabel

    2017-10-01

    Knowledge of the physiology underlying the autonomic nervous system is pivotal for understanding autonomic dysfunction in clinical practice. Autonomic dysfunction may result from primary modifications of the autonomic nervous system or be secondary to a wide range of diseases that cause severe morbidity and mortality. Together with a detailed history and physical examination, laboratory assessment of autonomic function is essential for the analysis of various clinical conditions and the establishment of effective, personalized and precise therapeutic schemes. This review summarizes the main aspects of autonomic medicine that constitute the background of cardiovascular autonomic dysfunction. Copyright © 2017 Sociedade Portuguesa de Cardiologia. Publicado por Elsevier España, S.L.U. All rights reserved.

  10. Birefringent light propagation on anisotropic cosmological backgrounds

    Science.gov (United States)

    Asenjo, Felipe A.; Hojman, Sergio A.

    2017-08-01

    Exact electromagnetic wave solutions to Maxwell equations on anisotropic Bianchi I cosmological spacetime backgrounds are studied. The waves evolving on Bianchi I spacetimes exhibit birefringence (associated with linear polarization) and dispersion. The particular case of a vacuum-dominated anisotropic Universe, which reproduces a Friedmann-Robertson-Walker Universe (for late times)—while, for earlier times, it matches a Kasner Universe—is studied. The electromagnetic waves do not, in general, follow null geodesics. This produces a modification of the cosmological redshift, which is then dependent on light polarization, its dispersion, and its non-null geodesic behavior. New results presented here may help to tackle some issues related to the "horizon" problem.

  11. Parental socioeconomic background and child behaviour

    DEFF Research Database (Denmark)

    Quinto Romani, Annette

    2014-01-01

    Although childhood obesity has long been in focus, little is known about the sensitivity of behavioural choices to measure parental resource constraints. The aim of this study is to examine the heterogeneous effects of children’s (or their parents’) choices of lifestyle subject to information...... and resource constraints, respectively. We address this issue using a unique longitudinal data set of almost 1,500 schoolchildren attending state schools between 2008 and 2010 in the Danish Municipality of Aalborg. One empirical strategy is to control for a rich set of child and parental characteristics......; another is to use child fixed effect to control for fixed unobserved child characteristics. By including the interaction between child behaviour and parental socioeconomic background, a more complete but more complex picture arises. Our findings challenge the predominant assumption that behaviour...

  12. Immunology and Homeopathy. 1. Historical Background

    Directory of Open Access Journals (Sweden)

    Paolo Bellavite

    2005-01-01

    Full Text Available Homeopathy was born as an experimental discipline, as can be seen from the enormous amount of homeopathic data collected over more than two centuries. However, the medical tradition of homeopathy has been separated from that of conventional science for a long time. Conventional scientific wisdom dictates that homeopathy should have no effect above placebo but experiments on ultra-high dilutions of solutes together with some clinical data suggest the intriguing possibility that it might do in some circumstances. Today, an osmotic process between disciplines, previously seen as in conflict, is facilitated because over the last few decades homeopathy has initiated the methods of current medical science and a substantial number of experimental studies—at molecular, cellular and clinical levels—are available. One area of dialogue and of common progress is that of inflammation and immunity, probably because these are closely related to the traditional ‘vital force’ of the body's self-healing power. In a series of papers we review the historical origins of homeopathy, the laboratory and animal models related to the field of immunopharmacology, the clinical evidence in favor and against the use of homeopathy in the inflammatory diseases and the hypotheses regarding its action mechanism(s. Finally, we will enlighten the specific characteristics of the homeopathic approach, which places great emphasis on identifying a cure for the whole organism.

  13. Autoerotic death due to electrocution

    Directory of Open Access Journals (Sweden)

    Piotr Arkuszewski

    2014-08-01

    Full Text Available Autoerotic death is a very rare case in forensic medicine. It is usually caused by asphyxia, but other reasons are also possible. Herein we present a case of autoerotic death due to electrocution caused by a self-made electrical device. The device was constructed to increase sexual feelings through stimulation of the scrotal area.

  14. Endocarditis due to Chryseobacterium meningosepticum

    Directory of Open Access Journals (Sweden)

    Bomb K

    2007-01-01

    Full Text Available Chryseobacterium meningosepticum is a gram negative rod widely distributed in nature. It is known to cause meningitis in neonates and premature infants. Adult infections are not common and are usually nosocomially acquired. We report an unusual case of native valve endocarditis in a 58-year-old man due to this organism. A high degree of suspicion and correct identification and sensitivity testing is required to diagnose infections by this rare isolate.

  15. Cosmic axion background propagation in galaxies

    Directory of Open Access Journals (Sweden)

    Francesca V. Day

    2016-02-01

    Full Text Available Many extensions of the Standard Model include axions or axion-like particles (ALPs. Here we study ALP to photon conversion in the magnetic field of the Milky Way and starburst galaxies. By modelling the effects of the coherent and random magnetic fields, the warm ionized medium and the warm neutral medium on the conversion process, we simulate maps of the conversion probability across the sky for a range of ALP energies. In particular, we consider a diffuse cosmic ALP background (CAB analogous to the CMB, whose existence is suggested by string models of inflation. ALP–photon conversion of a CAB in the magnetic fields of galaxy clusters has been proposed as an explanation of the cluster soft X-ray excess. We therefore study the phenomenology and expected photon signal of CAB propagation in the Milky Way. We find that, for the CAB parameters required to explain the cluster soft X-ray excess, the photon flux from ALP–photon conversion in the Milky Way would be unobservably small. The ALP–photon conversion probability in galaxy clusters is 3 orders of magnitude higher than that in the Milky Way. Furthermore, the morphology of the unresolved cosmic X-ray background is incompatible with a significant component from ALP–photon conversion. We also consider ALP–photon conversion in starburst galaxies, which host much higher magnetic fields. By considering the clumpy structure of the galactic plasma, we find that conversion probabilities comparable to those in clusters may be possible in starburst galaxies.

  16. Detection and correction of laser induced breakdown spectroscopy spectral background based on spline interpolation method

    Science.gov (United States)

    Tan, Bing; Huang, Min; Zhu, Qibing; Guo, Ya; Qin, Jianwei

    2017-12-01

    Laser-induced breakdown spectroscopy (LIBS) is an analytical technique that has gained increasing attention because of many applications. The production of continuous background in LIBS is inevitable because of factors associated with laser energy, gate width, time delay, and experimental environment. The continuous background significantly influences the analysis of the spectrum. Researchers have proposed several background correction methods, such as polynomial fitting, Lorenz fitting and model-free methods. However, less of them apply these methods in the field of LIBS Technology, particularly in qualitative and quantitative analyses. This study proposes a method based on spline interpolation for detecting and estimating the continuous background spectrum according to its smooth property characteristic. Experiment on the background correction simulation indicated that, the spline interpolation method acquired the largest signal-to-background ratio (SBR) over polynomial fitting, Lorenz fitting and model-free method after background correction. These background correction methods all acquire larger SBR values than that acquired before background correction (The SBR value before background correction is 10.0992, whereas the SBR values after background correction by spline interpolation, polynomial fitting, Lorentz fitting, and model-free methods are 26.9576, 24.6828, 18.9770, and 25.6273 respectively). After adding random noise with different kinds of signal-to-noise ratio to the spectrum, spline interpolation method acquires large SBR value, whereas polynomial fitting and model-free method obtain low SBR values. All of the background correction methods exhibit improved quantitative results of Cu than those acquired before background correction (The linear correlation coefficient value before background correction is 0.9776. Moreover, the linear correlation coefficient values after background correction using spline interpolation, polynomial fitting, Lorentz

  17. Return to work following sickness absence due to infectious mononucleosis

    NARCIS (Netherlands)

    Koopmans, P.C.; Bakhtali, R.; Katan, A.A.; Groothoff, J.W.; Roelen, C.A.

    BACKGROUND: Epstein-Barr virus infectious mononucleosis among adults is notorious because of the prolonged incapacitating fatigue it causes. AIMS: To investigate the duration of sickness absence and return to work following infectious mononucleosis. METHODS: Episodes of sickness absence due to

  18. Congenital adrenal hyperplasia due to 21-hydroxylase deficiency in ...

    African Journals Online (AJOL)

    Congenital adrenal hyperplasia due to 21-hydroxylase deficiency in South Africa. Y Ganie, C Aldous, Y Balakrishna, R Wiersma. Abstract. Background. Congenital adrenal hyperplasia (CAH) caused by deficiency of the 21-hydoxylase (21-OH) enzyme is the most common form of CAH worldwide. Objective. To evaluate the ...

  19. Hypothermia due to Antipsychotic Medication : A Systematic Review

    NARCIS (Netherlands)

    Zonnenberg, Cherryl; Bueno-de-Mesquita, Jolien M.; Ramlal, Dharmindredew; Blom, Jan Dirk

    2017-01-01

    Background: Hypothermia is a rare, but potentially fatal adverse effect of antipsychotic drug (APD) use. Although the opposite condition, hyperthermia, has been researched extensively in the context of the malignant antipsychotic syndrome, little is known about hypothermia due to APDs. Objective:

  20. Operating limitations due to low gas temperature

    Energy Technology Data Exchange (ETDEWEB)

    Bruschi, R.; Ghiselli, W.; Spinazze, M.

    1995-12-31

    A number of projects concerning continental links for the transport of treated natural gas over long distance, both on and offshore, have been implemented during the last few years or are currently being implemented. The long trunklines in North America and subsea trunklines planned or already in operation in the North Sea, are outstanding examples of such long distance transmission of gas in large diameter pipelines operated at high pressure. The development of such network has paid special attention to the effects that low temperature resulting from the transportation process may imply in terms of pipe structural integrity and environmental impact. Scope of this paper is to discuss operating limitations due to low gas temperature. New project scenarios are presented in a brief introduction. The fluido-thermo-dynamic background for the development of low temperatures are outlined. Finally some topics relevant to structural integrity are discussed in particular such as the pipe steel behaviour at low temperature, the prediction techniques of the ice bulb growth around the pipe, the interactions of the cold line with the soil and the consequences due to the differential compliancy of the pipeline towards points of fixity (in-line valves/tees or fixed plants). 30 refs., 22 figs., 1 tab.

  1. Allergic contact cheilitis due to lipstick

    Directory of Open Access Journals (Sweden)

    Yatty Ravitasari

    2015-12-01

    Full Text Available Background: Cheilitis is a common problem of unknown etiology. A possible cause of cheilitis is contact allergy. Drugs, lipsticks, sunblock and toothpaste are the most common implicated allergens. Allergic contact cheilitis is a chronic superficial inflammatory disorder of the vermilion borders characterized by desquamation due to delayed-type hypersensitivity reaction. Purpose: We report a management of Allergic contact cheilitis due to lipsticks. Case: A 21-year-old woman had a history of atopic allergy to eggs, milk, and chicken presented with sore, dry, fissured, scaled and sometimes bleeding lip, over a 3-month period after application of a lipstick. Her symptoms persisted despite treatments with hydrocortisone cream. The patient provided a detailed history and underwent physical examination and patch tests to cosmetic components and patch test to her own lipstick. The patient had strongly-positive result to the tested lipstick. A diagnosis of allergic contact cheilitis was made based on the history and clinical findings. Case management: Patient was advised to avoid wearing lipstick. To relieve symptoms, treatment was initiated with combined topical corticosteroid, antibiotic, and moisturizer. Conclusion: Contact allergy patients should be tested for both cosmetic component series and their own lipsticks to exclude exfolliative cheilitis, infection, or light actinic cheilitis as causal agents.

  2. Experimental application of QCD antennas

    Energy Technology Data Exchange (ETDEWEB)

    Bobrovskyi, Sergei

    2010-02-15

    A serious problem in searches for new physics at the LHC is the rejection of QCD induced multijet events. In this thesis the formalism of QCD antenna variables based on the SPHEL approximation of QCD matrix elements is applied for the rst time on experimentally reconstructed jets in order to discriminate QCD from supersymmetric processes. The new observables provide additional information with respect to traditional event shape variables. Albeit correlated with experimentally measured missing transverse energy, the variables can be used to improve the signal to background ratio. (orig.)

  3. Maculopathy due to drug inhalation.

    Science.gov (United States)

    Asensio-Sánchez, V M; Gonzalez-Buendia, L; Marcos-Fernández, M

    2014-08-01

    A case of maculopathy due to "poppers" is described. Poppers is a drug composed of various forms of alkyl nitrite. A 39 year-old man, who had been using poppers for years, was seen in the clinic with phosphenes, reduced visual acuity and central scotoma. The SD-OCT in the right eye showed disruption at the level of the IS/OS junction line. The SD-OCT scan in the left eye showed an outer rectangular retinal hole and an outer retinal cyst. Copyright © 2012 Sociedad Española de Oftalmología. Published by Elsevier Espana. All rights reserved.

  4. Robustness of cosmic neutrino background detection in the cosmic microwave background

    CERN Document Server

    Audren, Benjamin; Cuesta, Antonio J; Gontcho, Satya Gontcho A; Lesgourgues, Julien; Niro, Viviana; Pellejero-Ibanez, Marcos; Pérez-Ràfols, Ignasi; Poulin, Vivian; Tram, Thomas; Tramonte, Denis; Verde, Licia

    2015-01-01

    The existence of a cosmic neutrino background can be probed indirectly by CMB experiments, not only by measuring the background density of radiation in the universe, but also by searching for the typical signatures of the fluctuations of free-streaming species in the temperature and polarisation power spectrum. Previous studies have already proposed a rather generic parametrisation of these fluctuations, that could help to discriminate between the signature of ordinary free-streaming neutrinos, or of more exotic dark radiation models. Current data are compatible with standard values of these parameters, which seems to bring further evidence for the existence of a cosmic neutrino background. In this work, we investigate the robustness of this conclusion under various assumptions. We generalise the definition of an effective sound speed and viscosity speed to the case of massive neutrinos or other dark radiation components experiencing a non-relativistic transition. We show that current bounds on these effectiv...

  5. Genetic background of aggressive behaviour in dogs

    Directory of Open Access Journals (Sweden)

    Witold Stanisław Proskura

    2013-01-01

    Full Text Available The background of aggression is very complicated and the basis of its occurrence has not been well explained yet. It is thought that tendency to aggressiveness is an effect of both environmental and genetic factors. Aggression is a very undesirable behavioural trait in dogs living with humans. The aim of this study was to determine the relationship between two polymorphisms: DRD4 intron II VNTR and C/T substitution in exon I HTR2B genes and aggressive behaviour in dogs. The VNTR polymorphism in the DRD4 gene was detected by agarose gel electrophoresis following PCR amplification, whereas C/T substitution in the HTR2B gene was analysed using amplification created restriction site-polymerase chain reaction (ACRS-PCR. A total of 121 dogs of several breeds were analyzed. All animals were classified based on a veterinary interview and observation in two groups: aggressive (n = 21 and non-aggressive (n = 100. Significant differences in DRD4 genotype frequencies between aggressive and non-aggressive dogs were observed (P DRD4 gene with the occurrence of aggressive behaviour in dogs. Moreover, the findings give good justification for further research aimed at evaluation of the possibility of using this genetic marker in Marker-assisted Selection.

  6. Time-dependent Backgrounds Of String Theory

    CERN Document Server

    Maloney, A D

    2003-01-01

    This thesis is devoted to the study of time-dependent backgrounds in string theory. The first chapter contains a brief, non-technical introduction to the subject. In the second chapter quantum field theory in d-dimensional de Sitter space is studied, with an emphasis on the dS/CFT correspondence. We study a one-parameter family of dS-invariant vacua; this bulk vacuum dependence is dual to a deformation of the boundary CFT by a marginal operator. In odd spacetime dimensions the state with no particles on I- has no particles on I+ , implying the absence of particle production. In Kerr-dS, a thermal density matrix is found by tracing over causally inaccessible modes. Assuming Cardy's formula, the microscopic entropy of such a thermal state in the boundary CFT precisely equals the Bekenstein-Hawking value. Next, we construct de Sitter vacua of supercritical string theories in D > 10 dimensions. Compactifying D − 4 of these dimensions on a carefully constructed asymmetric orientifold projects out t...

  7. External costs of aviation. Background report

    Energy Technology Data Exchange (ETDEWEB)

    Dings, J.M.W.; Wit, R.C.N.; Leurs, B.A.; De Bruyn, S.M.; Davidson, M.D. [CE, Delft (Netherlands); Fransen, W. [INTEGRAL Knowledge Utilization, Landsmeer (Netherlands)

    2002-02-01

    Besides numerous benefits to citizens and companies, air transport also brings undesired side-effects such as emissions and noise nuisance. Most of these negative 'external' effects, as they are called, are currently not priced or only to a limited degree. Consequently, the market place creates insufficient incentives to reduce these external effects. The study, commissioned by the German Umweltbundesamt, aims to contribute to the ongoing international process to create market-based incentives to the aviation industry to reduce the environmental impact of aviation. It does to by assessing, within margins as small as possible, external costs of aviation. The report at hand is a background report to the study 'External costs of aviation'. It contains four technical annexes. The first annex contains an overview of the international literature on the valuation of greenhouse gas emissions. The second annex describes the dependence of climatic impact of aviation on the occurrence of contrails, and the dependence of contrail formation on operational circumstances. The third annex contains an assessment of international literature on the valuation of non-greenhouse gas emissions, such as NOx and SO2. The fourth annex contains a short description of the methodology by which emissions and noise are allocated to passenger and freight transport in this study.

  8. Background simulation for the COBRA-experiment

    Energy Technology Data Exchange (ETDEWEB)

    Quante, Thomas [TU Dortmund, Institut fuer Physik (Germany); Collaboration: COBRA-Collaboration

    2015-07-01

    COBRA is a next-generation experiment searching for neutrinoless double beta (0νββ) decay using CdZnTe semiconductor detectors. The main focus is on {sup 116}Cd, with a Q-value of 2813.5 keV well above the highest dominant naturally occurring gamma lines. By measuring the half-life of the 0νββ decay, it is possible to clarify the nature of the neutrino as either Dirac or Majorana particle and furthermore to determine the effective Majorana mass. COBRA is currently in the demonstrator phase to study possible background contributions and gain information about the longterm stability of the used detectors. For this purpose a demonstrator array made up of 64 Cadmium-Zinc-Telluride (CdZnTe) semiconductor detectors in coplanar grid configuration was designed and realised at the Gran Sasso Underground laboratory (LNGS) in Italy. Simulations of the whole demonstrator setup are ongoing to reproduce the measured spectra for each detector. This is done in two steps. The first uses the Geant4 based framework VENOM for tracking and energy deposition inside each detector. Detector effects like the energy resolution and electron trapping have to be applied in the second step. The used detector geometry has to be verified against calibration measurements. This talk gives an overview of the current simulation status.

  9. Measurement of fast neutron background in SAGE

    CERN Document Server

    Abdurashitov, J N; Kalikhov, A V; Matushko, V L; Shikhin, A A; Yants, V E; Zaborskaia, O S

    2002-01-01

    The spectrometer intended for direct measurements of ultra low fluxes of fast neutrons is described. It is sensitive to neutron fluxes of 10 sup - sup 7 cm sup - sup 2 s sup - sup 1 and lower. The detection efficiency of fast neutrons with simultaneous energy measurement was determined from Monte-Carlo simulation to be equal to 0.11 +- 0.01. The background counting rate in the detector corresponds to a neutron flux of (6.5 +- 2.1) x 10 sup - sup 7 cm sup - sup 2 s sup - sup 1 in the range 1.0-11.0 MeV. The natural neutron flux from the surrounding mine rock at the depth of 4700 meters of water equivalent was measured to be (7.3 +- 2.4) x 10 sup - sup 7 cm sup - sup 2 s sup - sup 1 in the range 1.0-11.0 MeV. The flux of fast neutrons in the SAGE main room was measured to be < 2.3 x 10 sup - sup 7 cm sup - sup 2 s sup - sup 1 in 1.0-11.0 MeV energy range.

  10. The superhealing MRL background improves muscular dystrophy

    Directory of Open Access Journals (Sweden)

    Heydemann Ahlke

    2012-12-01

    Full Text Available Abstract Background Mice from the MRL or “superhealing” strain have enhanced repair after acute injury to the skin, cornea, and heart. We now tested an admixture of the MRL genome and found that it altered the course of muscle pathology and cardiac function in a chronic disease model of skeletal and cardiac muscle. Mice lacking γ-sarcoglycan (Sgcg, a dystrophin-associated protein, develop muscular dystrophy and cardiomyopathy similar to their human counterparts with limb girdle muscular dystrophy. With disruption of the dystrophin complex, the muscle plasma membrane becomes leaky and muscles develop increased fibrosis. Methods MRL/MpJ mice were bred with Sgcg mice, and cardiac function was measured. Muscles were assessed for fibrosis and membrane leak using measurements of hydroxyproline and Evans blue dye. Quantitative trait locus mapping was conducted using single nucleotide polymorphisms distinct between the two parental strains. Results Introduction of the MRL genome reduced fibrosis but did not alter membrane leak in skeletal muscle of the Sgcg model. The MRL genome was also associated with improved cardiac function with reversal of depressed fractional shortening and the left ventricular ejection fraction. We conducted a genome-wide analysis of genetic modifiers and found that a region on chromosome 2 was associated with cardiac, diaphragm muscle and abdominal muscle fibrosis. Conclusions These data are consistent with a model where the MRL genome acts in a dominant manner to suppress fibrosis in this chronic disease setting of heart and muscle disease.

  11. Astronomical background of global huge earthquakes

    Science.gov (United States)

    Hu, Hui; Han, Yan-Ben

    2006-03-01

    This paper analyzes the astronomical background of the global huge earthquakes with M≥8.5. The result shows that most of the earthquakes has occurred in the seismic belts (regions) where is being corresponding seismic active period with the lunar path, solar active falling period and accelerating period of earth rotation. This is as for the variation of long period of astronomical factors. For the variation of short period of astronomical factors, whether for local time or local sidereal time and lunar phase there is the phenomenon of occurrence of concentrating a interval time for the earthquakes. For the short variation of earth rotation this phenomenon is clear; either the earthquakes occur in most fast or in lowest of earth rotation. The above-mentioned results indicate that the eartquakes occurrence is affected by astronomical factors. The astronomical factors are one of motive force causing earthquake from external world. The astronomical factors with long period may act as modulation for the earthquake-pregnant process. And the astronomical factors with short period will causing huge fluctuations of the system and earthquake occur when it act on seismic structure of away from balance state.

  12. Silicon Nitride Background in Nanophotonic Waveguide Enhanced Raman Spectroscopy

    Directory of Open Access Journals (Sweden)

    Ashim Dhakal

    2017-02-01

    Full Text Available Recent studies have shown that evanescent Raman spectroscopy using a silicon nitride (SiN nanophotonic waveguide platform has higher signal enhancement when compared to free-space systems. However, signal-to-noise ratio from the waveguide at a low analyte concentration is constrained by the shot-noise from the background light originating from the waveguide itself. Hence, understanding the origin and properties of this waveguide background luminescence (WGBL is essential to developing mitigation strategies. Here, we identify the dominating component of the WGBL spectrum composed of a broad Raman scattering due to momentum selection-rule breaking in amorphous materials, and several peaks specific to molecules embedded in the core. We determine the maximum of the Raman scattering efficiency of the WGBL at room temperature for 785 nm excitation to be 4.5 ± 1 × 10−9 cm−1·sr−1, at a Stokes shift of 200 cm−1. This efficiency decreases monotonically for higher Stokes shifts. Additionally, we also demonstrate the use of slotted waveguides and quasi-transverse magnetic polarization as some mitigation strategies.

  13. Literacies for Surveillance: Social Network Sites and Background Investigations

    Directory of Open Access Journals (Sweden)

    Sarah Jackson Young

    2015-09-01

    Full Text Available In September 2013, civilian contractor Aaron Alexis entered the Washington Navy Yard and murdered twelve people before being fatally shot by police. This incident, together with an incident three months earlier involving Edward Snowden, caused the U.S. government to critically examine their background investigation (BI process; because both Snowden and Alexis had supposedly slipped through the cracks of their investigations, there must be some flaw in the BI procedure. The U.S. Committee on Oversight and Reform concluded that rules forbidding “background checkers from looking at the Internet or social media when performing checks” was one of the main factors contributing to defective BIs (Report, 2014. Since the report’s release, the Director of National Intelligence has been debating and trialing whether information from the Internet should be used to form a data double for BIs (Kopp, 2014; Rockwell, 2014. Using this conversation as a discussion catalyst, I argue that due to the nature of the data double, if the United States were to adopt the use of social networking sites (SNSs for security clearance purposes, neglecting to take into account basic principles of SNSs into the process of BIs may lead to misinformation and unfavorable adjudication. Ultimately, being literate about the social practices involved in SNSs and surveillance would benefit not only investigators, but anyone, including academics, looking at individuals in online spaces.

  14. Terrorist Screening and Brady Background Checks for Firearms

    National Research Council Canada - National Science Library

    Krouse, William J

    2005-01-01

    .... For a time, moreover, all Brady background check records for approved firearm transfers were destroyed almost immediately, precluding the opportunity to used the background check system to screen...

  15. The Chemical Background for Sensory Quality

    DEFF Research Database (Denmark)

    Zhang, Shujuan

    ; detecting changes of volatiles as a result of production errors in chocolate production, and monitoring aroma release provide useful information to food sensory quality control. For each application, both techniques were faced with challenges that need to be handled in different ways. Due to the complex......In the food industry, high sensory quality and stability of products are crucial factors for consumer satisfaction and market shares. Sensory quality is normally being evaluated by two major approaches: instrumental (volatile and nonvolatile compounds) approach and sensory approach by trained...... or consumer panels. Sensory evaluation is a primary measurement for providing immediate information of human perception on the products. Instrumental methods give objective analysis of compounds that potentially contribute to food flavour. These two kinds of analysis, basically, give different types...

  16. Effect of background electrolytes on gypsum dissolution

    Science.gov (United States)

    Burgos-Cara, Alejandro; Putnis, Christine; Ruiz-Agudo, Encarnacion

    2015-04-01

    Knowledge of the dissolution behaviour of gypsum (CaSO4· 2H2O) in aqueous solutions is of primary importance in many natural and technological processes (Pachon-Rodriguez and Colombani, 2007), including the weathering of rocks and gypsum karst formations, deformation of gypsum-bearing rocks, the quality of drinking water, amelioration of soil acidity, scale formation in the oil and gas industry or measurement of water motion in oceanography. Specific ions in aqueous solutions can play important but very different roles on mineral dissolution. For example, the dissolution rates and the morphology of dissolution features may be considerably modified by the presence of the foreign ions in the solution, which adsorb at the surface and hinder the detachment of the ions building the crystal. Dissolution processes in the aqueous environment are closely related to the rearrangement of water molecules around solute ions and the interaction between the solvent molecules themselves. The rearrangement of water molecules with respect to solute species has been recognized as the main kinetic barrier for crystal dissolution in many systems (Davis, 2000; De Yoreo and Dove 2004; Wasylenki et al. 2005). Current research suggest that the control that electrolytes exert on water structure is limited to the local environment surrounding the ions and is not related to long-range electric fields emanating from the ions but results from effects associated with the hydration shell(s) of the ions (Collins et al. 2007) and the ions' capacity to break or structure water (i.e. chaotropic and kosmotropic ions, respectively). These effects will ultimately affect the kinetics of crystal dissolution, and could be correlated with the water affinity of the respective background ions following a trend known as the lyotropic or Hofmeister series (Kunz et al. 2004; Dove and Craven, 2005). In situ macroscopic and Atomic Force Microscopy (AFM) flow-through dissolution experiments were conducted at a

  17. [Robotics in gynecology. Background, feasibility and applicability].

    Science.gov (United States)

    Ayala Yáñez, Rodrigo; Olaya Guzmán, Emilio José; Haghenbeck Altamirano, Francisco Javier

    2012-06-01

    Robotic surgery is a technology that emerged from the fusion and improvement of laparoscopy, robotics and telepresence. All these three technologies underwent a long experimentation process in which several applications and innovations were tested until the only system approved for use in humans was developed: the Da Vinci system by Intuitive Surgical Inc. Gynecology, being one of the pioneer branches of Medicine involved in the development of laparoscopy, is one of the fields with the greatest possibilities for robotics, which offers great diversity of applications in hysterectomies, myomectomies, endometriosis, and in the fields of urogynecology and, most importantly, oncology. There are no publications in Mexico with a proper description of the clinical experience with gynecologic robotic surgery, though a great amount of clinical experience has been accumulated in institutions that already have such equipment. A serious evaluation of the cost-benefit ratio is required because of the high cost of this technology. Evaluate and analyze the accumulated experience on this technology of foreign institutions in order to assess the benefits, cost and effectiveness of robotic surgery. The key to the optimal use of robotic technology is to diminish costs and speed the learning curve, and this implies the entry of other systems into the market as well as institutions with a high volume of patients and determined to invest in a highly trained and skilled surgical team. In order to recommend its implementation in our country an assessment of the efficiency and advantages of robotic technology considering institutional needs is mandatory.

  18. Preservice Teachers' Attitudes toward Inclusion and toward Students with Special Educational Needs from Different Ethnic Backgrounds

    Science.gov (United States)

    Markova, Maria; Pit-Ten Cate, Ineke; Krolak-Schwerdt, Sabine; Glock, Sabine

    2016-01-01

    Drawing on social cognition frameworks, we experimentally examined preservice teachers' implicit attitudes toward students with special educational needs (SEN) from different ethnic backgrounds and preservice teachers' explicit attitudes toward inclusive education. Preservice teachers (N = 46) completed an evaluative priming task and…

  19. [Infections due to Mycobacterium simiae].

    Science.gov (United States)

    García-Martos, Pedro; García-Agudo, Lidia; González-Moya, Enrique; Galán, Fátima; Rodríguez-Iglesias, Manuel

    2015-10-01

    Mycobacterium simiae is a slow-growing photochromogenic environmental mycobacterium, first described in 1965. Rarely associated with human infections, possibly due to its limited pathogenicity, it mainly produces lung infection in immunocompetent elderly patients with underlying lung disease, and in disseminated infections in immunosuppressed young patients with AIDS. A microbiological culture is needed to confirm the clinical suspicion, and genetic sequencing techniques are essential to correctly identify the species. Treating M. simiae infections is complicated, owing to the multiple resistance to tuberculous drugs and the lack of correlation between in vitro susceptibility data and in vivo response. Proper treatment is yet to be defined, but must include clarithromycin combined with other antimicrobials such as moxifloxacin and cotrimoxazole. It is possible that M. simiae infections are undiagnosed. Copyright © 2013 Elsevier España, S.L.U. y Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica. All rights reserved.

  20. Spectral measurements of the cosmic microwave background

    Energy Technology Data Exchange (ETDEWEB)

    Kogut, A.J.

    1989-04-01

    Three experiments have measured the intensity of the Cosmic Microwave Background (CMB) at wavelengths 4.0, 3.0, and 0.21 cm. The measurement at 4.0 cm used a direct-gain total-power radiometer to measure the difference in power between the zenith sky and a large cryogenic reference target. Foreground signals are measured with the same instrument and subtracted from the zenith signal, leaving the CMB as the residual. The reference target consists of a large open-mouth cryostat with a microwave absorber submerged in liquid helium; thin windows block the radiative heat load and prevent condensation atmospheric gases within the cryostat. The thermodynamic temperature of the CMB at 4.0 cm is 2.59 +- 0.07 K. The measurement at 3.0 cm used a superheterodyne Dicke-switched radiometer with a similar reference target to measure the zenith sky temperature. A rotating mirror allowed one of the antenna beams to be redirected to a series of zenith angles, permitting automated atmospheric measurements without moving the radiometer. A weighted average of 5 years of data provided the thermodynamic temperature of the CMB at 3.0 cm of 2.62 +- 0.06 K. The measurement at 0.21 cm used Very Large Array observations of interstellar ortho-formaldehyde to determine the CMB intensity in molecular clouds toward the giant HII region W51A (G49.5-0.4). Solutions of the radiative transfer problem in the context of a large velocity gradient model provided estimates of the CMB temperature within the foreground clouds. Collisional excitation from neutral hydrogen molecules within the clouds limited the precision of the result. The thermodynamic temperature of the CMB at 0.21 cm is 3.2 +- 0.9 K. 72 refs., 27 figs., 38 tabs.

  1. Climate Impacts on Northern Canada: Regional Background

    Energy Technology Data Exchange (ETDEWEB)

    Prowse, Terry D.; Peters, Daniel L. (Water and Climate Impacts Research Centre, Environment Canada, Dept. of Geography, Univ. of Victoria, Victoria, BC (Canada)). e-mail: terry.prowse@ec.gc.caa; Furgal, Chris (Indigenous Environmental Studies Program, Trent Univ., Peterborough, ON (Canada)); Bonsal, Barrie R. (National Water Research Inst., National Hydrology Research Centre, Environment Canada, Saskatoon, SK (Canada))

    2009-07-15

    Understanding the implications of climate change on northern Canada requires a background about the size and diversity of its human and biogeophysical systems. Occupying an area of almost 40% of Canada, with one-third of this contained in Arctic islands, Canada's northern territories consist of a diversity of physical environments unrivaled around the circumpolar north. Major ecozones composed of a range of landforms, climate, vegetation, and wildlife include: Arctic, boreal and taiga cordillera; boreal and taiga plains; taiga shield; and northern and southern Arctic. Although generally characterized by a cold climate, there is an enormous range in air temperature with mean annual values being as high as -5 deg C in the south to as low as -20 deg C in the high Arctic islands. A similar contrast characterizes precipitation, which can be >700 mm y-1 in some southern alpine regions to as low as 50 mm y-1 over islands of the high Arctic. Major freshwater resources are found within most northern ecozones, varying from large glaciers or ice caps and lakes to extensive wetlands and peat lands. Most of the North's renewable water, however, is found within its major river networks and originates in more southerly headwaters. Ice covers characterize the freshwater systems for multiple months of the year while permafrost prevails in various forms, dominating the terrestrial landscape. The marine environment, which envelops the Canadian Arctic Archipelago, is dominated by seasonal to multiyear sea ice often several meters thick that plays a key role in the regional climate. Almost two-thirds of northern Canadian communities are located along coastlines with the entire population being just over 100 000. Most recent population growth has been dominated by an expansion of nonaboriginals, primarily the result of resource development and the growth of public administration. The economies of northern communities, however, remain quite mixed with traditional land

  2. Ultra-low background DNA cloning system.

    Directory of Open Access Journals (Sweden)

    Kenta Goto

    Full Text Available Yeast-based in vivo cloning is useful for cloning DNA fragments into plasmid vectors and is based on the ability of yeast to recombine the DNA fragments by homologous recombination. Although this method is efficient, it produces some by-products. We have developed an "ultra-low background DNA cloning system" on the basis of yeast-based in vivo cloning, by almost completely eliminating the generation of by-products and applying the method to commonly used Escherichia coli vectors, particularly those lacking yeast replication origins and carrying an ampicillin resistance gene (Amp(r. First, we constructed a conversion cassette containing the DNA sequences in the following order: an Amp(r 5' UTR (untranslated region and coding region, an autonomous replication sequence and a centromere sequence from yeast, a TRP1 yeast selectable marker, and an Amp(r 3' UTR. This cassette allowed conversion of the Amp(r-containing vector into the yeast/E. coli shuttle vector through use of the Amp(r sequence by homologous recombination. Furthermore, simultaneous transformation of the desired DNA fragment into yeast allowed cloning of this DNA fragment into the same vector. We rescued the plasmid vectors from all yeast transformants, and by-products containing the E. coli replication origin disappeared. Next, the rescued vectors were transformed into E. coli and the by-products containing the yeast replication origin disappeared. Thus, our method used yeast- and E. coli-specific "origins of replication" to eliminate the generation of by-products. Finally, we successfully cloned the DNA fragment into the vector with almost 100% efficiency.

  3. CS2 analysis in presence of non-Gaussian background noise - Effect on traditional estimators and resilience of log-envelope indicators

    Science.gov (United States)

    Borghesani, P.; Antoni, J.

    2017-06-01

    Second-order cyclostationary (CS2) analysis has become popular in the field of machine diagnostics and a series of digital signal processing techniques have been developed to extract CS2 components from the background noise. Among those techniques, squared envelope spectrum (SES) and cyclic modulation spectrum (CMS) have gained popularity thanks to their high computational efficiency and simple implementation. The effectiveness of CMS and SES has been previously quantified based on the hypothesis of Gaussian background noise and has led to statistical tests for the presence of CS2 peaks in squared envelope spectra and cyclic modulation spectra. However a recently established link of CMS with SES and of SES with kurtosis has exposed a potential weakness of those indicators in the case of highly leptokurtic background noise. This case is often present in practice when the machine is subjected to highly impulsive phenomena, either due to harsh operating conditions or to electric noise generated by power electronics and captured by the sensor. This study investigates and quantifies for the first time the effect of leptokurtic noise on the capabilities of SES and CMS, by analysing three progressively harsh situations: high kurtosis, infinite kurtosis and alpha-stable background noise (for which even first and second-order moments are not defined). Then the resilience of a recently proposed family of CS2 indicators, based on the log-envelope, is verified analytically, numerically and experimentally in the case of highly leptokurtic noise.

  4. Improvement of the experimental validation of the DARWIN code system due to the JEFF3.1 library for UOX spent fuel inventory and decay heat calculation - synthesis of the tendencies obtained with the MALIBU international benchmark and the French Post-Irradiation Examination database

    Energy Technology Data Exchange (ETDEWEB)

    Eschbach, Romain; Riffard, Cecile; San Felice, Laurence; Marimbeau, Pierre; Venard, Christophe [CEA/DEN/DER/SPRC, CE Cadarache, St Paul-Lez-Durance (France); Laugier, Frederic [EdF, R and D, 1 av. General de Gaulle, 92131 Clamart Cedex (France); Thro, Jean-Francois [AREVA-NC, Tour Areva, 92084 Paris La Defense (France)

    2008-07-01

    This paper deals with the experimental qualification of the French package DARWIN for the PWR UOX fuel inventory calculation, focused on the isotopes involved in Burnup Credit (BUC) applications and decay heat calculation. The calculation - experiment (C/E-1) discrepancies are calculated with the latest European Evaluation File JEFF3 associated with the SHEM energy mesh, and compared with the previous results obtained with JEF2.2. An overview of the tendencies for the JEFF3 / JEF2 comparison is obtained on a complete range of burnup from 10 to 70 GWd/t, from the French Post Irradiation Examination (P.I.E.) database and the experimental results obtained in the framework of the international benchmark MALIBU. For the most previously unsatisfactory isotopes ({sup 236}U, {sup 242}Pu/{sup 243}Am, {sup 143}Nd, {sup 147,150,152}Sm, {sup 155}Gd and {sup 153,154,155}Eu), the (C/E-1) trends are considerably reduced. Uncertainty on decay heat calculation is systematically reduced with JEFF3, especially for short and very long cooling time, up to 40 % compared to JEF2.2 (authors)

  5. Onychomycosis due to opportunistic molds*

    Science.gov (United States)

    Martínez-Herrera, Erick Obed; Arroyo-Camarena, Stefanie; Tejada-García, Diana Luz; Porras-López, Carlos Francisco; Arenas, Roberto

    2015-01-01

    BACKGROUND: Onychomycosis are caused by dermatophytes and Candida, but rarely by non- dermatophyte molds. These opportunistic agents are filamentous fungi found as soil and plant pathogens. OBJECTIVES: To determine the frequency of opportunistic molds in onychomycosis. METHODS: A retrospective analysis of 4,220 cases with onychomycosis, diagnosed in a 39-month period at the Institute of Dermatology and Skin surgery "Prof. Dr. Fernando A. Cordero C." in Guatemala City, and confirmed with a positive KOH test and culture. RESULTS: 32 cases (0.76%) of onychomycosis caused by opportunistic molds were confirmed. The most affected age group ranged from 41 to 65 years (15 patients, 46.9%) and females were more commonly affected (21 cases, 65.6%) than males. Lateral and distal subungual onychomycosis (OSD-L) was detected in 20 cases (62.5%). The microscopic examination with KOH showed filaments in 19 cases (59.4%), dermatophytoma in 9 cases (28.1%), spores in 2 cases (6.25%), and filaments and spores in 2 cases (6.25%). Etiologic agents: Aspergillus sp., 11 cases (34.4%); Scopulariopsis brevicaulis, 8 cases (25.0%); Cladosporium sp., 3 cases (9.4%); Acremonium sp., 2 cases (6.25%); Paecilomyces sp., 2 cases (6.25%); Tritirachium oryzae, 2 cases (6.25%); Fusarium sp., Phialophora sp., Rhizopus sp. and Alternaria alternate, 1 case (3.1%) each. CONCLUSIONS: We found onychomycosis by opportunistic molds in 0.76% of the cases and DLSO was present in 62.5%. The most frequent isolated etiological agents were: Aspergillus sp. and Scopulariopsis brevicaulis. PMID:26131862

  6. A Questionnaire Study of Food – Drug Interactions to Assess Knowledge of People from Diverse Backgrounds

    OpenAIRE

    Sana Afrooz Sajid; Ruqiya Sultana; Muna Masaratunnisa; Shobia Naaz; Mir S. Adil

    2017-01-01

    Background: Food drug interactions contribute a major reason for drug interactions but they are neglected due to less knowledge and awareness on it. Objective: To assess the awareness about food drug interactions among various individuals from diverse backgrounds. Methodology: This is the prospective questionnaire study comprising of 12 questions, each question have both right and wrong options, where as the last question is opinion based. The questionnaire was formatted in a simple a...

  7. An Investigation of Backgrounds in the DEAP-3600 Dark Matter Direct Detection Experiment

    Science.gov (United States)

    Veloce, Laurelle Maria

    Astronomical and cosmological observations reveal that the majority of the matter in our universe is made of an unknown, non-luminous substance called dark matter. Many experimental attempts are underway to directly detect particle dark matter, which is very difficult to measure due to the expected low interaction rate with normal matter. DEAP-3600 is a direct dark matter search experiment located two kilometres underground at SNOLAB, in Sudbury, Ontario. DEAP-3600 will make use of liquid argon as the detector material, which scintillates as charged particles pass through. The work presented here is an investigation of expected background sources in the DEAP detector. Because DEAP-3600 is a noble liquid-based experiment, a thin film of [1,1,4,4]-tetraphenyl-[1,3]-butadiene (TPB) is coated on the detector walls to shift the scintillation peak from the UV to visible regime for detection. However, alphas passing through TPB produce scintillation signals which can mimic recoil events. Because scintillation properties can change with temperature, we have conducted an investigation of alpha-induced TPB scintillation at temperatures ranging from 300 K to 3.4 K. We were able to characterize the light yield and decay times, and demonstrated that these background events should be distinguishable from true recoil events in liquid argon, thus enabling DEAP-3600 to achieve higher dark matter sensitivity. Additionally, we investigate the performance of the liquid argon purification systems, specifically the activated charcoal used for radon filtration. Previous measurements with the DEAP prototype experiment have demonstrated the necessity of removing radon from the argon prior to filling the detector, due to the release of contaminates from the argon storage systems. Charcoal radon filters are extremely efficient, however, if the emanation rate of the charcoal is too high, there is the possibility of re-contamination. We performed a measurement of the radon emanation rate of a

  8. Persuasion in Experimental Ultimatum Games

    DEFF Research Database (Denmark)

    Andersson, Ola; Galizzi, Matteo; Hoppe, Tim

    2008-01-01

     This paper experimentally studies persuasion effects in ultimatum games and finds that Proposers' payoffs significantly increase if, along with offers, they can send messages which Responders read before their acceptance decision. Higher payoffs are due to higher acceptance rates as well as more...

  9. Socialcultural background of formation of classical metaphysics

    Directory of Open Access Journals (Sweden)

    I. Z. Derzhko

    2014-09-01

    Full Text Available The classical model of philosophy has shaped ideas about its nature and aims that were laid in ancient metaphysics, but have been substantially amended by civilizational change. Socialcultural background of philosophy became trends that began to emerge in late medieval culture has particularly flourished there during modern times. Sphere of existence is important for the development of any spiritual phenomenon. For metaphysics it is the idea of humanity, acting as a kind of cultural protest against the domination of religion. This caused criticism of the medieval way of life and thinking. The idea of human revival based on spirit of antiquity has grounded. Disclaimer theological philosophy medieval variant type is as opposed to free philosophizing, coupled with poetry and literature, University dogmatic philosophy. There were a «rediscovery» of Plato, Aristotle reinterpretation. Philosophers explored a problem of human emotions and relationships, considering the person as a whole being, which is inherent in the mind, which cannot be considered without bodily desires and emotions. Change of the values awakened activity of the human person, led its transformation settings concerning himself and the surrounding world. Thus objectively obtained expression and ideological embodiment of civilization in a need of a new type of man - to a much greater extent compared to medieval activity, initiative, freedom, rationality, responsibility. Under the influence of such attitudes changes within religion gradually took place. Through the efforts of thinkers like Luther, Calvin, Munzer there were laid ideas of the Reformation that go far beyond its borders, gaining general cultural nature. The Church was increasingly losing control over everyday human existence. Gradually standards of a free, relaxed life became conventional; requirements of the body, «earthly» spirit demands fulfilling played a huge role. Thought and Culture of the Renaissance reflects

  10. [Fetal uropathies: anatomo-pathologic background].

    Science.gov (United States)

    Caruso, G; Pece, A; Botticella, M A; Caniglia, A

    1997-06-01

    The kidney malformations are complex anatomo-clinical entities that can be described with different classification approaches, based on morphological or etiopathogenetic criteria. The most serious fetal uropathies can be associated with the oligohydramnios sequence, due to insufficient urine escretion, related, for example to bilateral renal agenesis. A second malformation sequence can also be present, the so-called prune belly syndrome, in which an early urethral obstruction can produce abnormal bladder distension and finally renal dysplasia and globous dilation of the abdomen. The anatomo-pathological experience of the last ten years in the Institute of Pathological Anatomy of the University of Bari is based upon 154 cases of congenital uropathies in second trimester fetuses. Almost 80% of these cases presented also other associated anomalies, both chromosomal and non chromosomal syndromic or in casual combination. The possible echographic recognition of these pathologies, together with genetic and anatomopathological studies allow to categorize the fetal uropathies in two groups: the first characterized by an early or late obstruction of the urinary tract, in "sensu strictu" the true obstructive uropathies, and the second, formed by different morphologies all genetically determined.

  11. Fatigue crack growth due to overloads in plain concrete using ...

    Indian Academy of Sciences (India)

    The predicted results are compared with experimental crack growth data for variable amplitude loading and are found to capture the overload effect with sufficient accuracy. Through a sensitivity analysis, fracture toughness is found to be the most dominant parameter in accelerating the crack length due to application of ...

  12. Pulmonary Complications due to Esophagectomy.

    Science.gov (United States)

    Shirinzadeh, Abulfazl; Talebi, Yashar

    2011-01-01

    Esophageal carcinoma is the scourge of human beings. Pulmonary complications in patients who have undergone operation are common (20-30% of cases) and there are no suitable tools and ways to predict these complications. During a period of 10 years, from March 1998 to February 2007, 200 patients (150 male and 50 female) underwent Esophagectomy due to esophageal carcinoma in thoracic surgery ward retrospectively. Complications include the length of hospitalization, mechanical ventilation, morbidity and mortality. Patients' risk factors include age, preoperative chemo-radiotherapy, stage of the disease and preoperative spirometry condition. WE GROUPED OUR PATIENTS INTO THREE CATEGORIES: Normal (FEV1 ≥ 80% predicted), mildly impaired (FEV1 65% to 79% predicted), more severely impaired (FEV1 atelectasia in 160 patients (80%). 24 patients needed chest-tube insertion. 20 patients (10%) developed ARDS. 14 patients (7%) developed chylothorax. 20 patients (10%) of patients died during their postoperative hospital stay. 30 patients (15%) required mechanical ventilation for greater than 48 hours. We reviewed a number of preoperative clinical variables to determine whether they contributed to postoperative pulmonary complications as well as other outcomes. In general, age, impaired pulmonary function especially in those patients with FEV1 less than 65% predicted was associated with prolonged hospital length of stay (LOS). In fact pulmonary complications rate after Esophagectomy are high and there was associated mortality and morbidity.

  13. Transient hypofibrinogenemia due to allopurinol

    Directory of Open Access Journals (Sweden)

    Yin ZQ

    2014-09-01

    Full Text Available ZhiQiang Yin,1,* JiaLi Xu,2,* YongQiang Li,3,* JiPing Xia,1 Dan Luo1 1Department of Dermatology, 2Department of Oncology, 3Department of Rehabilitation Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China *These authors contributed equally to this work Abstract: This study reports a case of an 80-year-old male who suffered from drug eruption due to oral allopurinol for the treatment of gout. This patient complained of widespread erythema and maculopapule with itch, and small quantities of purplish-red rash with diffused distribution on four limbs were noted. After he was hospitalized, the area with purpuric rash increased in size, and hypofibrinogenemia was found. After treatment with intravenous infusion of fibrinogen and cryoprecipitate, and continued treatment with high-dose methylprednisolone, the skin rash gradually went away. This is the first report of purpura and hypofibrinogenemia induced by allopurinol and the pathophysiology underlying this reaction remained unknown. Keywords: purpura, fibrinogen, drug eruption, gout

  14. [Organ alterations due to aging].

    Science.gov (United States)

    Wieczorowska-Tobis, Katarzyna

    2008-01-01

    Aging defined as progressive organ dysfunction which makes keeping homeostasis more difficult starts at the age of 30-40. However, due to difficulties with the distinction between aging and disease processes, changes previously believed to be caused by aging are often recognized as the effect of pathologies when new data is presented. According to current knowledge, cardio-vascular aging includes decreased elasticity of main arteries, decreased ability of left ventricule to relaxate, diminished function of sino-atrial node and decreased effect of beta-adrenergic stimulation. Aging in the respiratory system is attributed to increased size of alveoli and alveolar ducts (which easier collapse), a decrease in the gase exchange area, a decrease in respiratory volumes (both static and dynamic) and a severe decrease in maximal oxygen consumption. In aging kidneys both renal blood flow and glomerular filtration are decreased. As the result of tubular alterations the kidney ability to conserve and dilute urine, and its capability to regulate the pH and serum sodium level diminish. Less dramatic changes are seen in the gastrointestinal tract. According to available data, high prevalence of gastric atrophy and hypochlorhydria are a consequence of Helicobacter pylori infection. Also, constipation is attributed much more to sedative life style and diet than to aging itself. In summary, none of the presented alterations is severe enough to cause the disease, but all of them increase the risk of pathology and thus pave the way for the disease even in healthy elderly subjects.

  15. Experimental search for quantum gravity

    CERN Document Server

    2018-01-01

    This book summarizes recent developments in the research area of quantum gravity phenomenology. A series of short and nontechnical essays lays out the prospects of various experimental possibilities and their current status. Finding observational evidence for the quantization of space-time was long thought impossible. In the last decade however, new experimental design and technological advances have changed the research landscape and opened new perspectives on quantum gravity. Formerly dominated by purely theoretical constructions, quantum gravity now has a lively phenomenology to offer. From high precision measurements using macroscopic quantum oscillators to new analysis methods of the cosmic microwave background, no stone is being left unturned in the experimental search for quantum gravity. This book sheds new light on the connection of astroparticle physics with the quantum gravity problem. Gravitational waves and their detection are covered. It illustrates findings from the interconnection between gene...

  16. Otomycosis due to filamentous fungi.

    Science.gov (United States)

    García-Agudo, Lidia; Aznar-Marín, Pilar; Galán-Sánchez, Fátima; García-Martos, Pedro; Marín-Casanova, Pilar; Rodríguez-Iglesias, Manuel

    2011-10-01

    Otomycosis is common throughout the world but barely studied in Spain. Our objective was to determine the microbiological and epidemiological characteristics of this pathology in Cadiz (Spain) between 2005 and 2010. Samples from patients with suspicion of otomycosis underwent a direct microscopic examination and culture on different media for fungi and bacteria. Mycological cultures were incubated at 30°C for at least seven days. Identification of fungi was based on colonial morphology and microscopic examination of fungal structure. From a total of 2,633 samples, microbial growth was present in 1,375 (52.2%) and fungal isolation in 390 (28.4%). We identified 228 yeasts and 184 filamentous fungi (13.4% of positive cultures and 47.2% of otomycosis), associated with yeasts in 22 cases (5.6%). The most frequent species were Aspergillus flavus (42.4%), A. niger (35.9%), A. fumigatus (12.5%), A. candidus (7.1%), A. terreus (1.6%), and Paecilomyces variotii (0.5%). Infection was predominant in men (54.9%) and patients beyond 55 years old (46.8%). The most common clinical symptoms were itching (98.9%), otalgia (59.3%), and hypoacusis (56.0%). Fall season reported the lowest number of cases (20.1%). Incidence of otomycosis and fungi producing otomycosis vary within the distinct geographical areas. In Cadiz, this infection is endemic due to warm temperatures, high humidity, sea bathing, and wind, which contributes to disseminate the conidia. Despite Aspergillus niger has been reported as the main causative agent, A. flavus is predominant in Cadiz. Although infection is usually detected in warm months, we observed a homogeneous occurrence of otomycosis in almost all the seasons.

  17. Epileptic seizures due to multiple cerebral cavernomatosis

    Directory of Open Access Journals (Sweden)

    Spasić Mirjana

    2007-01-01

    Full Text Available Background. Cavernous angiomas are angiographically occult vascular malformations that are present in 0.4−0.9 % of people, and represent around 5% of all cerebrovascular malformations. They can be single or multiple, and sporadic or familial. The presence of multiple lesions is more frequent in familial cavernomatosis. Ten to 30 % are associated with familial clustering. Case report. We presented the case of a 43-year-old man, admitted to the Emergency Department due to unprovoked seizure during the wide awake and everyday activities. Neurological examination was with no focal signs. A 32-channel standard digital EEG was without any significant changes of normal baseline activity. After sleep deprivation EEG showed multifocal, bilateral and asymmetric polyspikes and sharpwaves activity. Hyperventilation induced generalized epileptiform discharges. MRI scan demonstrated multiple small cavernous angiomas. Neuropsychological testing demonstrated a delayed memory impairment. Neurosurgery treatment was not recommended, and the therapy with valproate 1 250 mg/day had an excellent efficacy with no singnificant adverse effects. Conclusion. This patient considered as a rare case with multiple cavernomatosis highlights the importance of neuroradiological examination in adult patients with the first epileptic seizure but with no focal neurological signs. .

  18. Alpha particles diffusion due to charge changes

    Energy Technology Data Exchange (ETDEWEB)

    Clauser, C. F., E-mail: cesar.clauser@ib.edu.ar; Farengo, R. [Centro Atómico Bariloche and Instituto Balseiro, Comisión Nacional de Energía Atómica and Universidad Nacional de Cuyo, Av. Bustillo 9500, 8400 Bariloche (Argentina)

    2015-12-15

    Alpha particles diffusion due to charge changes in a magnetized plasma is studied. Analytical calculations and numerical simulations are employed to show that this process can be very important in the pedestal-edge-SOL regions. This is the first study that presents clear evidence of the importance of atomic processes on the diffusion of alpha particles. A simple 1D model that includes inelastic collisions with plasma species, “cold” neutrals, and partially ionized species was employed. The code, which follows the exact particle orbits and includes the effect of inelastic collisions via a Monte Carlo type random process, runs on a graphic processor unit (GPU). The analytical and numerical results show excellent agreement when a uniform background (plasma and cold species) is assumed. The simulations also show that the gradients in the density of the plasma and cold species, which are large and opposite in the edge region, produce an inward flux of alpha particles. Calculations of the alpha particles flux reaching the walls or divertor plates should include these processes.

  19. [Effects of exposure frequency and background information on preferences for photographs of cars in different locations].

    Science.gov (United States)

    Matsuda, Ken; Kusumi, Takashi; Hosomi, Naohiro; Osa, Atsushi; Miike, Hidetoshi

    2014-08-01

    This study examined the influence of familiarity and novelty on the mere exposure effect while manipulating the presentation of background information. We selected presentation stimuli that integrated cars and backgrounds based on the results of pilot studies. During the exposure phase, we displayed the stimuli successively for 3 seconds, manipulating the background information (same or different backgrounds with each presentation) and exposure frequency (3, 6, and 9 times). In the judgment phase, 18 participants judged the cars in terms of preference, familiarity, and novelty on a 7-point scale. As the number of stimulus presentations increased, the preference for the cars increased during the different background condition and decreased during the same background condition. This increased preference may be due to the increase in familiarity caused by the higher exposure frequency and novelty resulting from the background changes per exposure session. The rise in preference judgments was not seen when cars and backgrounds were presented independently. Therefore, the addition of novel features to each exposure session facilitated the mere exposure effect.

  20. Genomic consequences of background effects on scalloped mutant expressivity in the wing of Drosophila melanogaster.

    Science.gov (United States)

    Dworkin, Ian; Kennerly, Erin; Tack, David; Hutchinson, Jennifer; Brown, Julie; Mahaffey, James; Gibson, Greg

    2009-03-01

    Genetic background effects contribute to the phenotypic consequences of mutations and are pervasive across all domains of life that have been examined, yet little is known about how they modify genetic systems. In part this is due to the lack of tractable model systems that have been explicitly developed to study the genetic and evolutionary consequences of background effects. In this study we demonstrate that phenotypic expressivity of the scalloped(E3) (sd(E3)) mutation of Drosophila melanogaster is background dependent and is the result of at least one major modifier segregating between two standard lab wild-type strains. We provide evidence that at least one of the modifiers is linked to the vestigial region and demonstrate that the background effects modify the spatial distribution of known sd target genes in a genotype-dependent manner. In addition, microarrays were used to examine the consequences of genetic background effects on the global transcriptome. Expression differences between wild-type strains were found to be as large as or larger than the effects of mutations with substantial phenotypic effects, and expression differences between wild type and mutant varied significantly between genetic backgrounds. Significantly, we demonstrate that the epistatic interaction between sd(E3) and an optomotor blind mutation is background dependent. The results are discussed within the context of developing a complex but more realistic view of the consequences of genetic background effects with respect to mutational analysis and studies of epistasis and cryptic genetic variation segregating in natural populations.

  1. Sea-Based Infrared Scene Interpretation by Background Type Classification and Coastal Region Detection for Small Target Detection.

    Science.gov (United States)

    Kim, Sungho

    2015-09-23

    Sea-based infrared search and track (IRST) is important for homeland security by detecting missiles and asymmetric boats. This paper proposes a novel scheme to interpret various infrared scenes by classifying the infrared background types and detecting the coastal regions in omni-directional images. The background type or region-selective small infrared target detector should be deployed to maximize the detection rate and to minimize the number of false alarms. A spatial filter-based small target detector is suitable for identifying stationary incoming targets in remote sea areas with sky only. Many false detections can occur if there is an image sector containing a coastal region, due to ground clutter and the difficulty in finding true targets using the same spatial filter-based detector. A temporal filter-based detector was used to handle these problems. Therefore, the scene type and coastal region information is critical to the success of IRST in real-world applications. In this paper, the infrared scene type was determined using the relationships between the sensor line-of-sight (LOS) and a horizontal line in an image. The proposed coastal region detector can be activated if the background type of the probing sector is determined to be a coastal region. Coastal regions can be detected by fusing the region map and curve map. The experimental results on real infrared images highlight the feasibility of the proposed sea-based scene interpretation. In addition, the effects of the proposed scheme were analyzed further by applying region-adaptive small target detection.

  2. Appendectomy due to lead poisoning: a case-report

    OpenAIRE

    Aghilinejad M; AH Mehrparvar; Mohammadi S

    2008-01-01

    Abstract Background Lead poisoning is a common occupational health hazard in developing countries and many misdiagnoses and malpractices may occur due to unawareness of lead poisoning symptoms. Case presentation We report a case of occupational lead poisoning in an adult battery worker with abdominal colic who initially underwent appendectomy with removal of normal appendix. Later on he was diagnosed with lead poisoning and was treated appropriately with lead chelator (CaNa2EDTA). Conclusion ...

  3. EEG Beta Power but Not Background Music Predicts the Recall Scores in a Foreign-Vocabulary Learning Task

    National Research Council Canada - National Science Library

    Küssner, Mats B; de Groot, Annette M. B; Hofman, Winni F; Hillen, Marij A

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is-partly due to a lack of theory-driven research-no consistent evidence to support this notion...

  4. EEG Beta power but not background music predicts the recall scores in an foreign-vocobulary learning tast

    National Research Council Canada - National Science Library

    Küssner, M.B; de Groot, A.M.B; Hofman, W.F; Hillen, M.A

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is-partly due to a lack of theory-driven research-no consistent evidence to support this notion...

  5. Mitigation strategies against radiation-induced background for space astronomy missions

    Science.gov (United States)

    Davis, C. S. W.; Hall, D.; Keelan, J.; O'Farrell, J.; Leese, M.; Holland, A.

    2018-01-01

    The Advanced Telescope for High ENergy Astrophysics (ATHENA) mission is a major upcoming space-based X-ray observatory due to be launched in 2028 by ESA, with the purpose of mapping the early universe and observing black holes. Background radiation is expected to constitute a large fraction of the total system noise in the Wide Field Imager (WFI) instrument on ATHENA, and designing an effective system to reduce the background radiation impacting the WFI will be crucial for maximising its sensitivity. Significant background sources are expected to include high energy protons, X-ray fluorescence lines, 'knock-on' electrons and Compton electrons. Due to the variety of the different background sources, multiple shielding methods may be required to achieve maximum sensitivity in the WFI. These techniques may also be of great interest for use in future space-based X-ray experiments. Simulations have been developed to model the effect of a graded-Z shield on the X-ray fluorescence background. In addition the effect of a 90nm optical blocking filter on the secondary electron background has been investigated and shown to modify the requirements of any secondary electron shielding that is to be used.

  6. Cosmological Backgrounds of Gravitational Waves and eLISA/NGO: Phase Transitions, Cosmic Strings and Other Sources

    CERN Document Server

    Binétruy, Pierre; Caprini, Chiara; Dufaux, Jean-François

    2012-01-01

    We review the main cosmological backgrounds of gravitational waves accessible to detectors in space sensitive to the range $10^{-4}$ to $10^{-1}$ Hz, with a special emphasis on those backgrounds due to phase transitions or networks of cosmic strings. We apply this to identify the scientific potential of the NGO/eLISA mission of ESA, regarding the detectability of such cosmological backgrounds.

  7. EEG Beta Power but Not Background Music Predicts the Recall Scores in a Foreign-Vocabulary Learning Task

    OpenAIRE

    K?ssner, Mats B.; Groot, Annette M.B. de; Hofman, Winni F; Hillen, Marij A.

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is?partly due to a lack of theory-driven research?no consistent evidence to support this notion. We investigated inter-individual differences in the effects of background music on foreign vocabulary learning. Based on Eysenck?s theory of personality we predicted that individuals with a high level of cortical arousal should perform worse when learning with background music compared...

  8. EEG Beta power but not background music predicts the recall scores in an foreign-vocobulary learning tast

    OpenAIRE

    Küssner, M.B.; Groot, A.M.B. de; Hofman, W.F.; Hillen, M.A.

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is-partly due to a lack of theory-driven research-no consistent evidence to support this notion. We investigated inter-individual differences in the effects of background music on foreign vocabulary learning. Based on Eysenck's theory of personality we predicted that individuals with a high level of cortical arousal should perform worse when learning with background music compared...

  9. Electromagnetic Compatibility (EMC) and Noise Background Testing for Double Chooz PMT System

    Energy Technology Data Exchange (ETDEWEB)

    Cepero, J. R.; Encabo Fernandez, F. J.; Pepe, I.; Verdugo, A.

    2009-05-21

    The Double Chooz PMT system is a HV/signal splitter. In this report is presented an electromagnetic compatibility and background noise testing for the Double Chooz PMT system. It was possible to proceed the EMC testing on different grounding configurations of PMT splitter due to its special PCB design, endowed of jumping points and a metal box ground electrode. (Author)

  10. EEG Beta power but not background music predicts the recall scores in an foreign-vocobulary learning tast

    NARCIS (Netherlands)

    Küssner, M.B.; de Groot, A.M.B.; Hofman, W.F.; Hillen, M.A.

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is-partly due to a lack of theory-driven research-no consistent evidence to support this notion. We investigated inter-individual differences in the effects of background music on

  11. EEG Beta Power but Not Background Music Predicts the Recall Scores in a Foreign-Vocabulary Learning Task

    NARCIS (Netherlands)

    Küssner, Mats B.; de Groot, Annette M. B.; Hofman, Winni F.; Hillen, Marij A.

    2016-01-01

    As tantalizing as the idea that background music beneficially affects foreign vocabulary learning may seem, there is-partly due to a lack of theory-driven research-no consistent evidence to support this notion. We investigated inter-individual differences in the effects of background music on

  12. Detection of admittivity anomaly on high-contrast heterogeneous backgrounds using frequency difference EIT.

    Science.gov (United States)

    Jang, J; Seo, J K

    2015-06-01

    This paper describes a multiple background subtraction method in frequency difference electrical impedance tomography (fdEIT) to detect an admittivity anomaly from a high-contrast background conductivity distribution. The proposed method expands the use of the conventional weighted frequency difference EIT method, which has been used limitedly to detect admittivity anomalies in a roughly homogeneous background. The proposed method can be viewed as multiple weighted difference imaging in fdEIT. Although the spatial resolutions of the output images by fdEIT are very low due to the inherent ill-posedness, numerical simulations and phantom experiments of the proposed method demonstrate its feasibility to detect anomalies. It has potential application in stroke detection in a head model, which is highly heterogeneous due to the skull.

  13. The effect of background music in auditory health persuasion

    NARCIS (Netherlands)

    Elbert, Sarah; Dijkstra, Arie

    2013-01-01

    In auditory health persuasion, threatening information regarding health is communicated by voice only. One relevant context of auditory persuasion is the addition of background music. There are different mechanisms through which background music might influence persuasion, for example through mood

  14. Passive background correction method for spatially resolved detection

    Science.gov (United States)

    Schmitt, Randal L [Tijeras, NM; Hargis, Jr., Philip J.

    2011-05-10

    A method for passive background correction during spatially or angularly resolved detection of emission that is based on the simultaneous acquisition of both the passive background spectrum and the spectrum of the target of interest.

  15. Influence of Parental Educational Background on the Family Values ...

    African Journals Online (AJOL)

    Data was analysed with chi square test statistics using version 17 of SPSS. Results showed that fathers' educational background did not significantly influence family values among undergraduate students. However, mothers' educational background significantly influenced family values held by undergraduate students.

  16. Monitoring toxicity in anaerobic digesters by the rantox biosensor: theoretical background.

    Science.gov (United States)

    Rozzi, A; Tomei, M C; Di Pinto, A C; Limoni, N

    1997-07-05

    Process control of anaerobic reactors is difficult due to the complexity of the methabolic pathways in the microbial consortium and to the difficulty of detecting and monitoring process instability in short time, before the biomass is poisoned by incoming toxicants. Process control based on the Rantox biosensor is based on the following principle: the wastewater that can potentially induce an overload or contains a toxicant is first tested on a small "upstream" digester (the Rantox). This reactor makes possible to detect the potential instability and, if necessary, to divert the concentrated and/or contaminated wastewater to a buffer tank and consequently to protect the active biomass of the full-scale reactor. It is generally accepted that methanogens are the most sensitive microorganisms in anaerobic digestion. Among these bacteria, the acetoclastic methanogens are of primary importance because some 70% of the converted chemical oxyen demand (COD) mass flow passes through acetic acid. Therefore the first objective in the development of the Rantox biosensor has been to monitor the metabolism of acetoclastic methanogens in the presence of toxicants. This article presents the theoretical background required to evaluate the toxicity effects by determining the kinetic constants of the considered microorganisms from experimental data. The results of two series of calibration tests, performed in order to obtain a preliminary evaluation of the biosensor response to overload and toxicity conditions, are reported. In a second article, calibration tests will be described which refer to two prototypes of the biosensor tested in different operating conditions. The crucial point related to the Rantox, i.e., its comparison with a "normal" laboratory-scale digester to simulate a full-scale plant, will be the subject of the third (and last) article, which is planned to describe the development of this instrument.

  17. Evolution of the SOL plasma background at density shoulder formation

    Energy Technology Data Exchange (ETDEWEB)

    D' Isa, Federico Antonio; Carralero, Daniel; Lunt, Tilmann; Collaboration: ASDEX Upgrade Team

    2016-12-15

    observed that filaments, namely coherent structures that enhance the transport in the outer region of Tokamaks, undergo a regime transition that enhances their transport at the outboard midplane. It is believed that inhomogeneous perpendicular transport related to the filaments is responsible for the density shoulder formation. The regime transition occurs because of the increase of the global collisionality. Since the plasma parameters (n{sub e},T{sub e}) change significantly along a field line it is needed a full description of the plasma in the SOL in order to study where such increase of the collisionaly takes place. The first part of this work is focused on use EMC3-EIRENE simulations, in continuation of previous work, to provide a detailed 3D plasma background of the SOL condition in two different L-mode discharges carried out in the ASDEX Upgrade Tokamak, featuring different different degrees of shoulder formation: case A (simulation of discharge 29231) in which no shoulder is observed and case B (simulation of discharge 29887) after the transition. In the simulation, cross field transport is described by the perpendicular particle and energy diffusive time independent transport coefficients: D {sub perpendicular} {sub to}, χ {sup e,i} {sub perpendicular} {sub to}. The simulations are compared with the experimental measurements at the midplane, the X-point and the divertor targets. The comparison shows that previous simulations of case B strongly underestimate the electron and ion temperatures. In order to improve the simulation results and provide a realistic description of the SOL plasma background several simulations are performed. As a result, the final agreement between experimental measurement and numerical results has been improved with respect to the original work. The simulations show that: - It is possible to simulate the density shoulder formation by increasing transport a factor of 3 only at the outer midplane, in good agreement with the experimental

  18. Multi-scale MHD analysis of LHD plasma with background field changing

    Science.gov (United States)

    Ichiguchi, K.; Sakakibara, S.; Ohdachi, S.; Carreras, B. A.

    2015-04-01

    The mechanism of the partial collapse observed in the experiment with the background magnetic field changing in the Large Helical Device (LHD) is numerically investigated with a nonlinear magnetohydrodynamics (MHD) simulation. Since the different timescales of the perturbations and the background field changing have to be treated simultaneously for the analysis of this plasma, a multi-scale simulation scheme is developed. The effect of the perturbation dynamics on the equilibrium pressure and rotational transform is taken into account in this scheme. The result indicates that the collapse is caused by the destabilization of an infernal-like mode due to the magnetic hill enhanced by the change of the background field. The mechanism of the reduction of the central beta observed after the partial collapse in the experiment is also analysed in relation to the effect of the background field changing.

  19. A Batch-Incremental Video Background Estimation Model using Weighted Low-Rank Approximation of Matrices

    KAUST Repository

    Dutta, Aritra

    2017-07-02

    Principal component pursuit (PCP) is a state-of-the-art approach for background estimation problems. Due to their higher computational cost, PCP algorithms, such as robust principal component analysis (RPCA) and its variants, are not feasible in processing high definition videos. To avoid the curse of dimensionality in those algorithms, several methods have been proposed to solve the background estimation problem in an incremental manner. We propose a batch-incremental background estimation model using a special weighted low-rank approximation of matrices. Through experiments with real and synthetic video sequences, we demonstrate that our method is superior to the state-of-the-art background estimation algorithms such as GRASTA, ReProCS, incPCP, and GFL.

  20. Toward the estimation of background fluctuations under newly-observed signals in particle physics

    Science.gov (United States)

    Colecchia, Federico

    2015-01-01

    When the number of events associated with a signal process is estimated in particle physics, it is common practice to extrapolate background distributions from control regions to a predefined signal window. This allows accurate estimation of the expected, or average, number of background events under the signal. However, in general, the actual number of background events can deviate from the average due to fluctuations in the data. Such a difference can be sizable when compared to the number of signal events in the early stages of data analysis following the observation of a new particle, as well as in the analysis of rare decay channels. We report on the development of a data-driven technique that aims to estimate the actual, as opposed to the expected, number of background events in a predefined signal window. We discuss results on toy Monte Carlo data and provide a preliminary estimate of systematic uncertainty.

  1. The estimation of background production by cosmic rays in high-energy gamma ray telescopes

    Science.gov (United States)

    Edwards, H. L.; Nolan, P. L.; Lin, Y. C.; Koch, D. G.; Bertsch, D. L.; Fichtel, C. E.; Hartman, R. C.; Hunter, S. D.; Kniffen, D. A.; Hughes, E. B.

    1991-01-01

    A calculational method of estimating instrumental background in high-energy gamma-ray telescopes, using the hadronic Monte Carlo code FLUKA87, is presented. The method is applied to the SAS-2 and EGRET telescope designs and is also used to explore the level of background to be expected for alternative configurations of the proposed GRITS telescope, which adapts the external fuel tank of a Space Shuttle as a gamma-ray telescope with a very large collecting area. The background produced in proton-beam tests of EGRET is much less than the predicted level. This discrepancy appears to be due to the FLUKA87 inability to transport evaporation nucleons. It is predicted that the background in EGRET will be no more than 4-10 percent of the extragalactic diffuse gamma radiation.

  2. Suppression of the background coming from {sup 42}Ar in the GERDA experiment

    Energy Technology Data Exchange (ETDEWEB)

    Lubashevskiy, Alexey [Max-Planck-Institut fuer Kernphysik, Saupfercheckweg 1, D-69117 Heidelberg (Germany); Collaboration: GERDA-Collaboration

    2016-07-01

    The GERDA experiment aims at the 0νββ search in {sup 76}Ge. The search is performed with high purity germanium detectors operated in liquid argon. One of the most dangerous backgrounds in GERDA is the background from {sup 42}K which is a daughter isotope of cosmogenically produced {sup 42}Ar, presented in natural argon. {sup 42}K ions collect on the surface of the detector and increase its background level. Several ways to suppress such background has been investigated. The tests were performed at LArGe low-background test facility, which gives a possibility to operate bare detectors in about 1m{sup 3} of LAr. It is equipped with a scintillation veto, so particles which deposit part of their energy in LAr can be detected by PMTs. The experimental setup is located at LNGS underground laboratory close to GERDA experiment location. Different experimental techniques were tested together with pulse shape discrimination (PSD) method in order to suppress {sup 42}K background. The chosen solution for GERDA Phase II is so called ''nylon mini-shroud'' (NMS). It is made from nylon foil and covered with wavelength shifter from both sides. NMS allows to suppress collection of {sup 42}K ions towards to the surface significantly. It was demonstrated in LArGe that together with PSD and scintillation veto the {sup 42}K background can be suppressed in more than 1000 times. The results obtained during commissioning runs in GERDA Phase II are also presented.

  3. When is a background equivalent? Sparse chromatic context revisited

    NARCIS (Netherlands)

    Brenner, E; Cornelissen, FW

    Jenness and Shevell (Vision Res 1995,35:797-805) reported that a red background with white dots scattered on it has a different influence on a target's apparent colour than an equivalent uniform background. We show that this finding depends on what one considers an equivalent background. Jenness and

  4. Social Background Effects on School and Job Opportunities

    Science.gov (United States)

    Tampieri, Alessandro

    2016-01-01

    This paper proposes a theory on how students' social background affects their school attainment and job opportunities. I study a set-up where students differ in ability and social background, and I analyse the interaction between a school and an employer. Students with disadvantaged background are penalised compared to other students: they receive…

  5. Measurement of background translocation frequencies in individuals with clones

    Energy Technology Data Exchange (ETDEWEB)

    Wade, Marcelle J. [California State Univ. (CalState), Hayward, CA (United States)

    1996-08-01

    In the leukemia case the unseparated B and T lymphocytes had a high translocation frequency even after 0.0014, respectively. After purging all clones from the data, the translocation frequencies for Bio 8 and Bio 23 were 0.00750.0014 and 0.0073 metaphases were scored for chromosomal aberrations,, specifically reciprocal translocations, using fluorescence in situ hybridization (FISH). Metaphase spreads were used from two healthy, unexposed individuals (not exposed to radiation, chemotherapy or radiotherapy) and one early B- precursor acute lymphocytic leukemia (ALL) patient (metaphase spreads from both separated T lymphocytes and unseparated B and T lymphocytes were scored). All three individuals had an abnormally high translocation frequency. The high translocation frequencies resulted from clonal expansion of specific translocated chromosomes. I show in this thesis that by purging (discounting or removing) clones from the data of unexposed individuals, one can obtain true background translocation frequencies. In two cases, Bio 8 and Bio 23, the measured translocation frequency for chromosomes 1, 2 and 4 was 0.0124 purging all of the clones from the data. This high translocation frequency may be due to a low frequency of some clones and may not be recognized. The separated T lymphocytes had a higher translocation frequency than expected.

  6. Background exposure rates of terrestrial wildlife in England and Wales

    Energy Technology Data Exchange (ETDEWEB)

    Beresford, N.A. [Centre for Ecology and Hydrology, CEH-Lancaster, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP (United Kingdom)], E-mail: nab@ceh.ac.uk; Barnett, C.L. [Centre for Ecology and Hydrology, CEH-Lancaster, Lancaster Environment Centre, Library Avenue, Bailrigg, Lancaster LA1 4AP (United Kingdom); Jones, D.G. [British Geological Society, Keyworth, Nottingham NG12 5GG (United Kingdom); Wood, M.D. [Institute for Sustainable Water Integrated Management and Ecosystem Research (SWIMMER), Nicholson Building, University of Liverpool, Liverpool, Merseyside L69 3GP (United Kingdom); Appleton, J.D.; Breward, N. [British Geological Society, Keyworth, Nottingham NG12 5GG (United Kingdom); Copplestone, D. [Environment Agency, Richard Fairclough House, Knutsford Road, Warrington, Cheshire WA4 1HG (United Kingdom)

    2008-09-15

    It has been suggested that, when assessing radiation impacts on non-human biota, estimated dose rates due to anthropogenically released radionuclides should be put in context by comparison to dose rates from natural background radiation. In order to make these comparisons, we need data on the activity concentrations of naturally occurring radionuclides in environmental media and organisms of interest. This paper presents the results of a study to determine the exposure of terrestrial organisms in England and Wales to naturally occurring radionuclides, specifically {sup 40}K, {sup 238}U series and {sup 232}Th series radionuclides. Whole-body activity concentrations for the reference animals and plants (RAPs) as proposed by the ICRP have been collated from literature review, data archives and a targeted sampling campaign. Data specifically for the proposed RAP are sparse. Soil activity concentrations have been derived from an extensive geochemical survey of the UK. Unweighted and weighted absorbed dose rates were estimated using the ERICA Tool. Mean total weighted whole-body absorbed dose rates estimated for the selected terrestrial organisms was in the range 6.9 x 10{sup -2} to 6.1 x 10{sup -1} {mu}Gy h{sup -1}.

  7. A high resolution, low background fast neutron spectrometer

    CERN Document Server

    Abdurashitov, J N; Kalikhov, A V; Matushko, V L; Shikhin, A A; Yants, V E; Zaborskaia, O S; Adams, J M; Nico, J S; Thompson, A K

    2002-01-01

    We discuss the possibility to create a spectrometer of full absorption based on liquid scintillator doped with enriched sup 6 Li. Of specific interest, the spectrometer will have energy resolution estimated to lie in the range 5-10% for 14 MeV neutrons. It will be sensitive to fluxes from 10 sup - sup 4 to 10 sup 6 cm sup - sup 2 s sup - sup 1 above a threshold of 1 MeV in a gamma-background of up to 10 sup 4 s sup - sup 1. The detector's efficiency will be determined by the volume of the scintillator only (approx 3 l) and is estimated to be 0.2-10%. The main reason for the poor resolution of an organic scintillator based spectrometer of full absorption is a non-linear light-yield of the scintillator for recoil protons. The neutron energy is occasionally distributed among recoil protons, and due to non-linear light-yield the total amount of light from all recoil protons ambiguously determines the initial neutron energy. The high-energy resolution will be achieved by compensation of the non-linear light-yield ...

  8. Low fluorescence background electroblotting membrane for DNA sequencing.

    Science.gov (United States)

    Chu, T J; Caldwell, K D; Weiss, R B; Gesteland, R F; Pitt, W G

    1992-03-01

    A low fluorescence background polypropylene (PP) membrane has been developed for ultimate use as an electroblotting membrane in DNA sequencing based on fluorescence detection. The DNA binding capacity of this membrane is improved by a surface modification using radio frequency plasma discharge (RFPD) in ammonia gas. The RFPD operational parameters are evaluated both in terms of membrane nitrogen content and in terms of the product's capacity for binding radioisotope-labeled DNA fragments. The surface morphologies of the derivatized membranes are examined by scanning electron microscopy; their mechanical and electrical properties, which are important for the subsequent sequencing procedures, are likewise established. Due to the goal of developing a membrane suitable for multiplex processing, in which the electroblotted DNA must withstand dozens of hybridization/stripping cycles, special attention is given the covalent attachment of DNA to the membrane. The modified PP membrane is evaluated in a multiplex sequencing application using radioisotope-labeled DNA probes, and found to yield somewhat better binding of a given amount of electroblotted DNA than the commonly used GeneScreen membrane. A tenfold repetition of the probing indicates little loss of signal; the membrane-bound DNA is stable upon storage and shows no detectable loss in probing efficiency after one month.

  9. Target-to-background enhancement in multispectral endoscopy with background autofluorescence mitigation for quantitative molecular imaging

    Science.gov (United States)

    Yang, Chenying; Hou, Vivian W.; Girard, Emily J.; Nelson, Leonard Y.; Seibel, Eric J.

    2014-07-01

    Fluorescence molecular imaging with exogenous probes improves specificity for the detection of diseased tissues by targeting unambiguous molecular signatures. Additionally, increased diagnostic sensitivity is expected with the application of multiple molecular probes. We developed a real-time multispectral fluorescence-reflectance scanning fiber endoscope (SFE) for wide-field molecular imaging of fluorescent dye-labeled molecular probes at nanomolar detection levels. Concurrent multichannel imaging with the wide-field SFE also allows for real-time mitigation of the background autofluorescence (AF) signal, especially when fluorescein, a U.S. Food and Drug Administration approved dye, is used as the target fluorophore. Quantitative tissue AF was measured for the ex vivo porcine esophagus and murine brain tissues across the visible and near-infrared spectra. AF signals were then transferred to the unit of targeted fluorophore concentration to evaluate the SFE detection sensitivity for sodium fluorescein and cyanine. Next, we demonstrated a real-time AF mitigation algorithm on a tissue phantom, which featured molecular probe targeted cells of high-grade dysplasia on a substrate containing AF species. The target-to-background ratio was enhanced by more than one order of magnitude when applying the real-time AF mitigation algorithm. Furthermore, a quantitative estimate of the fluorescein photodegradation (photobleaching) rate was evaluated and shown to be insignificant under the illumination conditions of SFE. In summary, the multichannel laser-based flexible SFE has demonstrated the capability to provide sufficient detection sensitivity, image contrast, and quantitative target intensity information for detecting small precancerous lesions in vivo.

  10. Experimental determination of re-suspension data of particle-bound radioactive materials of relevant contaminated surfaces in case of radiological emergencies for the radioactive exposure assessment of the emergency staff and affected persons due to re-suspension; Experimentelle Bestimmung von Resuspensionsdaten partikelgebundener radioaktiver Stoffe von relevanten kontaminierten Oberflaechen bei radiologischen Notfaellen zur Beurteilung einer Exposition von Einsatzpersonal und betroffenen Personen durch Resuspension

    Energy Technology Data Exchange (ETDEWEB)

    Koch, Wolfgang; Loedding, Hubert; Lange, Florentin

    2012-01-15

    , beginning 5 minutes after the event, is obtained. As expected even under the conditions of enhanced resuspension rates at early times following the deposition event for a gamma-emitter such as Cs 137 the inhalation dose is on a very low level compared to external radiation exposure. The corresponding dose rate (committed effective dose) of 2200 {mu}Sv/h for the assumed plutonium release emphasizes the need of wearing level C protection such as a half-mask (e.g. FFP 3 respirator) in this case and gives support to the deployment of fixation measures in the early phase after such a radiological event. Indoor scenarios, such as those in emergency care centres, a facility for a contamination survey and initial treatment of people potentially affected by a nuclear power plant accident, were experimentally simulated in a ventilated clean room. These data can serve as input data for indoor air models to determine activity concentrations and inhaled dose rates of the emergency personnel. (orig.)

  11. Characterizing background error with the NASA GMAO OSSE

    Science.gov (United States)

    Errico, R. M.; Prive, N. C.

    2016-01-01

    Understanding the characteristics of background error is vital to the design and performance of data assimilation systems. However, the true state of the atmosphere is unknown, and qualitative determination of background error is thus a challenge. We present an exploration of background error characteristics using the NASA Global Modeling and Assimilation Office Observing System Simulation Experiment framework, where the presence of the Nature Run allows direct calculation of the background error. The behavior of the data assimilation system (DAS) can be compared with the character of the background error, and performance of the DAS will be investigated in a series of both idealized and realistic experiments.

  12. A salient region detection model combining background distribution measure for indoor robots.

    Science.gov (United States)

    Li, Na; Xu, Hui; Wang, Zhenhua; Sun, Lining; Chen, Guodong

    2017-01-01

    Vision system plays an important role in the field of indoor robot. Saliency detection methods, capturing regions that are perceived as important, are used to improve the performance of visual perception system. Most of state-of-the-art methods for saliency detection, performing outstandingly in natural images, cannot work in complicated indoor environment. Therefore, we propose a new method comprised of graph-based RGB-D segmentation, primary saliency measure, background distribution measure, and combination. Besides, region roundness is proposed to describe the compactness of a region to measure background distribution more robustly. To validate the proposed approach, eleven influential methods are compared on the DSD and ECSSD dataset. Moreover, we build a mobile robot platform for application in an actual environment, and design three different kinds of experimental constructions that are different viewpoints, illumination variations and partial occlusions. Experimental results demonstrate that our model outperforms existing methods and is useful for indoor mobile robots.

  13. Background studies of B → K{sup (*)} ν anti ν decays at Belle II

    Energy Technology Data Exchange (ETDEWEB)

    Kahn, James; Kuhr, Thomas [Ludwig-Maximilians University Munich (Germany); Collaboration: Belle II-Collaboration

    2016-07-01

    The B → K{sup (*)} ν anti ν decays provide some of the cleanest experimentally measurable instances of the flavour changing neutral current process b → sν anti ν, which presents an excellent opportunity to investigate physics beyond the standard model. The missing energies of the two neutrinos make the measurement experimentally challenging and require the full reconstruction of the spectator B meson in e{sup +}e{sup -} → Υ(4S) → B anti B events. Observation of the B → K{sup (*)} ν anti ν decays will only become possible with the large data set that will be collected at the upgraded Belle II detector at the SuperKEKB accelerator in Tsukuba, Japan. A challenge of this decay analysis will be the understanding and suppression of the backgrounds. New techniques will be required to identify and simulate background events in sufficient volumes for statistical analysis.

  14. Clinical observation of macroamylasemia in splenosis due to the posttraumatic splenectomy.

    Science.gov (United States)

    Gubergrits, Natalya B; Zubov, Aleksandr; Golubova, Oksana; Fomenko, Pavel; Byelyayeva, Nadezhda

    2014-07-28

    Article analyzes current data on macroamylasemia and splenosis, their etiology and diagnostics in particular. Authors presented their own clinical observation of a young woman who was diagnosed to have macroamylasemia on the background of splenosis due to the splenectomy after blunt abdominal injury. This is the first time such a combination of macroamylasemia on the background of splenosis has been described in the literature.

  15. PLANCK, the Satellite: a New Experimental Test of General Relativity

    Directory of Open Access Journals (Sweden)

    Rabounski D.

    2008-04-01

    Full Text Available If the origin of a microwave background (EMB is the Earth, what would be its density and associated dipole anisotropy measured at different altitudes from the surface of the Earth? The mathematical methods of the General Theory of Relativity are applied herein to answer these questions. The density of the EMB is answered by means of Einstein's equations for the electromagnetic field of the Earth. The dipole anisotropy, which is due to the rapid motion of the source (the Earth in the weak intergalactic field, is analysed by using the geodesic equations for light-like particles (photons, which are mediators for electromagnetic radiation. It is shown that the EMB decreases with altitude so that the density of its energy at the altitude of the COBE orbit (900km is 0.68 times less than that at the altitude of a U2 aeroplane (25km. Furthermore, the density at the 2nd Lagrange point (1.5 million km, the position of the WMAP and PLANCK satellites should be only 10$^{-7}$ of the value detected by a U2 aeroplane or at the COBE orbit. The dipole anisotropy of the EMB doesn't depend on altitude from the surface of the Earth, it should be the same irrespective of the altitude at which measurements are taken. This result is in support to the experimental and observational analysis conducted by P.-M.Robitaille, according to which the 2.7K microwave background, first observed by Penzias and Wilson, is not of cosmic origin, but of the Earth, and is generated by the oceans. WMAP indicated the same anisotropy of the microwave background at the 2nd Lagrange point that near the Earth. Therefore when PLANCK, which is planned on July, 2008, will manifest the 2.7K monopole microwave signal deceased at the 2nd Langrange point, it will be a new experimental verification of Einstein's theory.

  16. PLANCK, the Satellite: a New Experimental Test of General Relativity

    Directory of Open Access Journals (Sweden)

    Borissova L.

    2008-04-01

    Full Text Available If the origin of a microwave background (EMB is the Earth, what would be its density and associated dipole anisotropy measured at different altitudes from the surface of the Earth? The mathematical methods of the General Theory of Relativity are applied herein to answer these questions. The density of the EMB is answered by means of Einstein’s equations for the electromagnetic field of the Earth. The dipole anisotropy, which is due to the rapid motion of the source (the Earth in the weak intergalactic field, is analysed by using the geodesic equations for light-like particles (photons, which are mediators for electromagnetic radiation. It is shown that the EMB decreases with altitude so that the density of its energy at the altitude of the COBE orbit (900km is 0.68 times less than that at the altitude of a U2 aeroplane (25 km. Furthermore, the density at the 2nd Lagrange point (1.5 million km, the position of the WMAP and PLANCK satellites should be only 1E-7 of the value detected by a U2 aeroplane or at the COBE orbit. The dipole anisotropy of the EMB doesn’t depend on altitude from the surface of the Earth, it should be the same irrespective of the altitude at which measurements are taken. This result is in support to the experimental and observational analysis conducted by P.-M. Robitaille, according to which the 2.7 K microwave background, first observed by Penzias and Wilson, is not of cosmic origin, but of the Earth, and is generated by the oceans. WMAP indicated the same anisotropy of the microwave background at the 2nd Lagrange point that near the Earth. Therefore when PLANCK, which is planned on July, 2008, will manifest the 2.7 K monopole microwave signal deceased at the 2nd Langrange point, it will be a new experimental verification of Einstein’s theory.

  17. Modulation of the Object/Background Interaction by Spatial Frequency

    Directory of Open Access Journals (Sweden)

    Yanju Ren

    2011-05-01

    Full Text Available With regard to the relationship between object and background perception in the natural scene images, functional isolation hypothesis and interactive hypothesis were proposed. Based on previous studies, the present study investigated the role of spatial frequency in the relationship between object and background perception in the natural scene images. In three experiments, participants reported the object, background, or both after seeing each picture for 500 ms followed by a mask. The authors found that (a backgrounds were identified more accurately when they contained a consistent rather than an inconsistent object, independently of spatial frequency; (b objects were identified more accurately in a consistent than an inconsistent background under the condition of low spatial frequencies but not high spatial frequencies; (c spatial frequency modulation remained when both objects and backgrounds were reported simultaneously. The authors conclude that object/background interaction is partially dependent on spatial frequency.

  18. Leakage of colon anastomoses: development of an experimental model in pigs

    DEFF Research Database (Denmark)

    Nordentoft, Tyge; Sørensen, Michael

    2007-01-01

    Background: In order to investigate anastomotic leakage, a number of experimental animal studies have been previously carried out. Due to the low frequency of spontaneous anastomotic leakages, there have been studies on gastrointestinal anastomoses with iatrogenically produced leakages. A leakage...... model has only been developed in one gastric bypass study. The aim of the present study was to develop a leakage model of pig colon anastomoses. This type of study has never been performed before. Materials and Methods: Anastomosis was performed in 22 pigs. In all anastomoses a standardized rupture......: A model of anastomotic leakage on pig colon is developed with creation of a 21-mm rupture in the anastomotic line....

  19. Text - background polarity affects performance irrespective of ambient illumination and colour contrast.

    Science.gov (United States)

    Buchner, A; Baumgartner, N

    2007-07-01

    In a series of experiments, proofreading performance was consistently better with positive polarity (dark text on light background) than with negative polarity displays (light text on dark background). This positive polarity advantage was independent of ambient lighting (darkness vs. typical office illumination) and of chromaticity (black and white vs. blue and yellow). A final experiment showed that colour contrast (red text on green background) could not compensate for a lack of luminance contrast. Physiological measures of effort and strain (breathing rate, heart rate, heart rate variability and skin conductance level) and self-reported mood, fatigue, arousal, eyestrain, headache, muscle strain and back pain did not vary as a function of any of the independent variables, suggesting that participants worked equally hard in all experimental conditions, so that the interpretation of the primary performance measure was unlikely to be contaminated by a performance-effort trade-off.

  20. Experimental Engineering: Articulating and Valuing Design Experimentation

    DEFF Research Database (Denmark)

    Vallgårda, Anna; Grönvall, Erik; Fritsch, Jonas

    2017-01-01

    In this paper we propose Experimental Engineering as a way to articulate open- ended technological experiments as a legitimate design research practice. Experimental Engineering introduces a move away from an outcome or result driven design process towards an interest in existing technologies...

  1. The Effect of Background Music While Silent Reading on EFL Learners’ Reading Comprehension

    Directory of Open Access Journals (Sweden)

    sakineh sahebdel

    2014-05-01

    Full Text Available This study attempted to determine the effect of background music while silent reading on Iranian EFL learners’ reading comprehension. The participants were 57 Iranian EFL learners between the ages of 14 and 16 in two 3rd grade high schoolclasses at pre-intermediate proficiency level. Before treatment,both experimental and control groups took a reading comprehension pretest. In the experimental group, the researchers played Mozart sonatas as background music and asked them to read the passage silently and then answer the reading comprehension questions. In the control group, the procedure was the same, but no music was played while silent reading by the students. After ten sessions, the students of both groups were asked to answer another independent but parallel form of reading section of PET as their post-test. The independent samples t-testresultsindicated that the experimental group outperformed the control group in reading comprehension posttest, and listening to background music while silent reading had a significantly positive effect on Iranian EFL learners’ reading comprehension. The results of the present study have implications for EFL students, teachers, and teacher educators as well as syllabus designers and materials developers.

  2. The influence of migratory background and parental education on health care utilisation of children.

    Science.gov (United States)

    Rosenkötter, Nicole; van Dongen, Martien C J M; Hellmeier, Wolfgang; Simon, Klaus; Dagnelie, Pieter C

    2012-10-01

    School-entry screening data from North Rhine-Westphalia (NRW), Germany from 2007 were used to investigate child health care utilisation. We focussed on the influence of migratory background and parental education on children's (1) participation in regularly scheduled early recognition examinations, (2) immunisation uptake and (3) referrals due to a school-entry screen-detected complaint. The study sample consisted of 52,171 children out of 17 NRW districts. Bivariable, stratified and multivariable analyses were performed to identify relevant associations between social determinants and health care utilisation outcome parameters. Multivariable logistic regression showed that children belonging to families with a migratory background or low parental education were more likely to have an incomplete documentation of early recognition examinations and to be referred due to a new diagnosis. Children with migratory background were more likely to be sufficiently immunised than children with parents of German ethnicity. For all studied health care utilisation outcomes, kindergarten visit had a supportive effect. In general, the results of our regional study were in line with the results from national population-based studies. Additionally, a larger likelihood of referrals due to school-screen-detected deficits in children with migratory background or low parental education was detected.

  3. Beamstop-based low-background ptychography to image weakly scattering objects.

    Science.gov (United States)

    Reinhardt, Juliane; Hoppe, Robert; Hofmann, Georg; Damsgaard, Christian D; Patommel, Jens; Baumbach, Christoph; Baier, Sina; Rochet, Amélie; Grunwaldt, Jan-Dierk; Falkenberg, Gerald; Schroer, Christian G

    2017-02-01

    In recent years, X-ray ptychography has been established as a valuable tool for high-resolution imaging. Nevertheless, the spatial resolution and sensitivity in coherent diffraction imaging are limited by the signal that is detected over noise and over background scattering. Especially, coherent imaging of weakly scattering specimens suffers from incoherent background that is generated by the interaction of the central beam with matter along its propagation path in particular close to and inside of the detector. Common countermeasures entail evacuated flight tubes or detector-side beamstops, which improve the experimental setup in terms of background reduction or better coverage of high dynamic range in the diffraction patterns. Here, we discuss an alternative approach: we combine two ptychographic scans with and without beamstop and reconstruct them simultaneously taking advantage of the complementary information contained in the two scans. We experimentally demonstrate the potential of this scheme for hard X-ray ptychography by imaging a weakly scattering object composed of catalytic nanoparticles and provide the analysis of the signal-to-background ratio in the diffraction patterns. Copyright © 2016 Elsevier B.V. All rights reserved.

  4. Effects of background music on concentration of workers.

    Science.gov (United States)

    Huang, Rong-Hwa; Shih, Yi-Nuo

    2011-01-01

    Background music is a common element in daily living and the workplace. Determination of whether background music affects human work concentration is a relevant concern. Studies have found background music influences human behavior, and this study attempts to understand how background music and listener fondness for types of music affects worker concentration. This study analyzes how different types of background music--and how listeners' degree of preference for the background music--can affect listener concentration in attention testing through Randomized Controlled Trial (RCT). Data were collected from 89 workers. The participants ranged in age between 19 and 28 years old, with an average age of 24 years old. We conclude background music influenced listener attention. This influence has more to do with listener fondness for the music than with type of music. Compared to situations without background music, the likelihood of background music affecting test-taker attention performance is likely to increase with the degree to which the test-taker likes or dislikes the music. It is important not to select music that workers strongly like or dislike when making a selection of background music to avoid negatively affecting worker concentration.

  5. Liver tissue tolerance for irradiation : Experimental and clinical investigations

    NARCIS (Netherlands)

    Cromheecke, M; Konings, AWT; Szabo, BG; Hoekstra, HJ

    2000-01-01

    Radiation treatment of the liver for malignant disease has gained renewed interest due to newly developed treatment modalities. Still limited specific knowledge is available concerning liver damage following irradiation. Inconsistencies between reported animal experimental studies are largely due to

  6. Study of $\\gamma\\gamma$ Background in $e^{+}e^{-} \\to W^{+}W^{-}\

    CERN Document Server

    Battaglia, Marco; Battaglia, Marco; Schulte, Daniel

    2000-01-01

    The effect of the overlap of gamma gamma -> hadrons to H nu nu events has been studied for the case of the Tesla e+e- linear collider at 350 GeV. It was found that, due to the significant bunch length and the track extrapolation accuracy provided by the Vertex Tracker, the gamma gamma background to physics events can be substantially reduced, with moderate loss in reconstruction efficiency, by a combination of kinematical and vertex topology observables. The remaining background, being confined to very forward hadron production, does not significantly interfere with the event reconstruction.

  7. Simultaneous measurement of tritium and radiocarbon by ultra-low-background proportional counting.

    Science.gov (United States)

    Mace, Emily; Aalseth, Craig; Alexander, Tom; Back, Henning; Day, Anthony; Hoppe, Eric; Keillor, Martin; Moran, Jim; Overman, Cory; Panisko, Mark; Seifert, Allen

    2017-08-01

    Use of ultra-low-background capabilities at Pacific Northwest National Laboratory provide enhanced sensitivity for measurement of low-activity sources of tritium and radiocarbon using proportional counters. Tritium levels are nearly back to pre-nuclear test backgrounds (~2-8 TU in rainwater), which can complicate their dual measurement with radiocarbon due to overlap in the beta decay spectra. We present results of single-isotope proportional counter measurements used to analyze a dual-isotope methane sample synthesized from ~120mg of H2O and present sensitivity results. Copyright © 2017 Elsevier Ltd. All rights reserved.

  8. Experimental Design to Evaluate Directed Adaptive Mutation in Mammalian Cells

    Science.gov (United States)

    Chiaro, Christopher R; May, Tobias

    2014-01-01

    Background We describe the experimental design for a methodological approach to determine whether directed adaptive mutation occurs in mammalian cells. Identification of directed adaptive mutation would have profound practical significance for a wide variety of biomedical problems, including disease development and resistance to treatment. In adaptive mutation, the genetic or epigenetic change is not random; instead, the presence and type of selection influences the frequency and character of the mutation event. Adaptive mutation can contribute to the evolution of microbial pathogenesis, cancer, and drug resistance, and may become a focus of novel therapeutic interventions. Objective Our experimental approach was designed to distinguish between 3 types of mutation: (1) random mutations that are independent of selective pressure, (2) undirected adaptive mutations that arise when selective pressure induces a general increase in the mutation rate, and (3) directed adaptive mutations that arise when selective pressure induces targeted mutations that specifically influence the adaptive response. The purpose of this report is to introduce an experimental design and describe limited pilot experiment data (not to describe a complete set of experiments); hence, it is an early report. Methods An experimental design based on immortalization of mouse embryonic fibroblast cells is presented that links clonal cell growth to reversal of an inactivating polyadenylation site mutation. Thus, cells exhibit growth only in the presence of both the countermutation and an inducing agent (doxycycline). The type and frequency of mutation in the presence or absence of doxycycline will be evaluated. Additional experimental approaches would determine whether the cells exhibit a generalized increase in mutation rate and/or whether the cells show altered expression of error-prone DNA polymerases or of mismatch repair proteins. Results We performed the initial stages of characterizing our system

  9. Cosmic Microwave Background: cosmology from the Planck perspective

    Science.gov (United States)

    De Zotti, Gianfranco

    2017-08-01

    The Planck mission has measured the angular anisotropies in the temperature of the Cosmic Microwave Background (CMB) with an accuracy set by fundamental limits. These data have allowed the determination of the cosmological parameters with extraordinary precision. These lecture notes present an overview of the mission and of its cosmological results. After a short history of the project, the Planck instruments and their performances are introduced and compared with those of the WMAP satellite. Next the approach to data analysis adopted by the Planck collaboration is described. This includes the techniques for dealing with the contamination of the CMB signal by astrophysical foreground emissions and for determining cosmological parameters from the analysis of the CMB power spectrum. The power spectra measured by Planck were found to be very well described by the standard spatially flat six-parameter ΛCDM cosmology with a power-law spectrum of adiabatic scalar perturbations. This is a remarkable result, considering that the six parameters account for the about 2500 independent power spectrum values measured by Planck (the power was measured for about 2500 multipoles), not to mention the about one trillion science samples produced. A large grid of cosmological models was also explored, using a range of additional astrophysical data sets in addition to Planck and high-resolution CMB data from ground-based experiments. On the whole, the Planck analysis of the CMB power spectrum allowed to vary and determined 16 parameters. Many other interesting parameters were derived from them. Although Planck was not initially designed to carry out high accuracy measurements of the CMB polarization anisotropies, its capabilities in this respect were significantly enhanced during its development. The quality of its polarization measurements have exceeded all original expectations. Planck's polarisation data confirmed and improved the understanding of the details of the cosmological

  10. Radiation background with the CMS RPCs at the LHC

    CERN Document Server

    Costantini, Silvia; Cai, J.; Li, Q.; Liu, S.; Qian, S.; Wang, D.; Xu, Z.; Zhang, F.; Choi, Y.; Goh, J.; Kim, D.; Choi, S.; Hong, B.; Kang, J.W.; Kang, M.; Kwon, J.H.; Lee, K.S.; Lee, S.K.; Park, S.K.; Pant, L.M.; Mohanty, A.K.; Chudasama, R.; Singh, J.B.; Bhatnagar, V.; Mehta, A.; Kumar, R.; Cauwenbergh, S.; Cimmino, A.; Crucy, S.; Fagot, A.; Garcia, G.; Ocampo, A.; Poyraz, D.; Salva, S.; Thyssen, F.; Tytgat, M.; Zaganidis, N.; Doninck, W.V.; Cabrera, A.; Chaparro, L.; Gomez, J.P.; Gomez, B.; Sanabria, J.C.; Avila, C.; Ahmad, A.; Muhammad, S.; Shoaib, M.; Hoorani, H.; Awan, I.; Ali, I.; Ahmed, W.; Asghar, M.I.; Shahzad, H.; Sayed, A.; Ibrahim, A.; Aly, S.; Assran, Y.; Radi, A.; Elkafrawy, T.; Sharma, A.; Colafranceschi, S.; Abbrescia, M.; Calabria, C.; Colaleo, A.; Iaselli, G.; Loddo, F.; Maggi, M.; Nuzzo, S.; Pugliese, G.; Radogna, R.; Venditti, R.; Verwilligen, P.; Benussi, L.; Bianco, S.; Piccolo, D.; Paolucci, P.; Buontempo, S.; Cavallo, N.; Merola, M.; Fabozzi, F.; Iorio, O.M.; Braghieri, A.; Montagna, P.; Riccardi, C.; Salvini, P.; Vitulo, P.; Vai, I.; Magnani, A.; Dimitrov, A.; Litov, L.; Pavlov, B.; Petkov, P.; Aleksandrov, A.; Genchev, V.; Iaydjiev, P.; Rodozov, M.; Sultanov, G.; Vutova, M.; Stoykova, S.; Hadjiiska, R.; Ibargüen, H.S.; Morales, M.I.P.; Bernardino, S.C.; Bagaturia, I.; Tsamalaidze, Z.; Crotty, I.; Kim, M.S.

    2015-05-28

    The Resistive Plate Chambers (RPCs) are employed in the CMS experiment at the LHC as dedicated trigger system both in the barrel and in the endcap. This note presents results of the radiation background measurements performed with the 2011 and 2012 proton-proton collision data collected by CMS. Emphasis is given to the measurements of the background distribution inside the RPCs. The expected background rates during the future running of the LHC are estimated both from extrapolated measurements and from simulation.

  11. Measurement of Acceptable Noise Level with Background Music

    OpenAIRE

    Ahn, Hyun-Jung; Bahng, Junghwa; Lee, Jae Hee

    2015-01-01

    Background and Objectives Acceptable noise level (ANL) is a measure of the maximum background noise level (BNL) that a person is willing to tolerate while following a target story. Although researchers have used various sources of target sound in ANL measures, a limited type of background noise has been used. Extending the previous study of Gordon-Hickey & Moore (2007), the current study determined the effect of music genre and tempo on ANLs as possible factors affecting ANLs. We also investi...

  12. Dynamics of Magnetized Plasma Jets and Bubbles Launched into a Background Magnetized Plasma

    Science.gov (United States)

    Wallace, B.; Zhang, Y.; Fisher, D. M.; Gilmore, M.

    2016-10-01

    The propagation of dense magnetized plasma, either collimated with mainly azimuthal B-field (jet) or toroidal with closed B-field (bubble), in a background plasma occurs in a number of solar and astrophysical cases. Such cases include coronal mass ejections moving in the background solar wind and extragalactic radio lobes expanding into the extragalactic medium. Understanding the detailed MHD behavior is crucial for correctly modeling these events. In order to further the understanding of such systems, we are investigating the injection of dense magnetized jets and bubbles into a lower density background magnetized plasma using a coaxial plasma gun and a background helicon or cathode plasma. In both jet and bubble cases, the MHD dynamics are found to be very different when launched into background plasma or magnetic field, as compared to vacuum. In the jet case, it is found that the inherent kink instability is stabilized by velocity shear developed due to added magnetic tension from the background field. In the bubble case, rather than directly relaxing to a minimum energy Taylor state (spheromak) as in vacuum, there is an expansion asymmetry and the bubble becomes Rayleigh-Taylor unstable on one side. Recent results will be presented. Work supported by the Army Research Office Award No. W911NF1510480.

  13. Beamstrahlung and QED backgrounds at future linear colliders

    Energy Technology Data Exchange (ETDEWEB)

    Schroeder, D.V.

    1990-10-01

    This dissertation is a detailed study of several aspects of beamstrahlung and related phenomena. The problem is formulated as the relativistic scattering of an electron from a strong but slowly varying potential. The solution is readily interpreted in terms of a classical electron trajectory, and differs from the solution of the corresponding classical problem mainly in the effect of quantum recoil due to the emission of hard photons. When the general solution is expanded for the case of an almost-uniform field, the leading term is identical to the well-known formula for quantum synchrotron radiation. The first non-leading term is negligible in all cases of interest where the expansion is valid. In applying the standard synchrotron radiation formula to the beamstrahlung problem, the effects of radiation reaction on the emission of multiple photons can be significant for some machine designs. Another interesting feature is the helicity dependence of the radiation process, which is relevant to the case where the electron beam is polarized. The inverse process of coherent electron-positron pair production by a beamstrahlung photon is a potentially serious background source at future colliders, since low-energy pairs can exit the bunch at a large angle. Pairs can also be produced incoherently by the collision of the two photons, either real or virtual. The rates, spectra, and angular distributions for both the coherent and incoherent processes are estimated here. At a 1/2 TeV machine the incoherent process will be more common, resulting in roughly 10{sup 6} pairs per bunch crossing. One member of each pair is always pushed outward, at an angle determined by its energy, by the field of the oncoming bunch. In addition, a small number of pairs are initially produced with a comparable or larger angle.

  14. Binary electrokinetic separation of target DNA from background DNA primers.

    Energy Technology Data Exchange (ETDEWEB)

    James, Conrad D.; Derzon, Mark Steven

    2005-10-01

    This report contains the summary of LDRD project 91312, titled ''Binary Electrokinetic Separation of Target DNA from Background DNA Primers''. This work is the first product of a collaboration with Columbia University and the Northeast BioDefense Center of Excellence. In conjunction with Ian Lipkin's lab, we are developing a technique to reduce false positive events, due to the detection of unhybridized reporter molecules, in a sensitive and multiplexed detection scheme for nucleic acids developed by the Lipkin lab. This is the most significant problem in the operation of their capability. As they are developing the tools for rapidly detecting the entire panel of hemorrhagic fevers this technology will immediately serve an important national need. The goal of this work was to attempt to separate nucleic acid from a preprocessed sample. We demonstrated the preconcentration of kilobase-pair length double-stranded DNA targets, and observed little preconcentration of 60 base-pair length single-stranded DNA probes. These objectives were accomplished in microdevice formats that are compatible with larger detection systems for sample pre-processing. Combined with Columbia's expertise, this technology would enable a unique, fast, and potentially compact method for detecting/identifying genetically-modified organisms and multiplexed rapid nucleic acid identification. Another competing approach is the DARPA funded IRIS Pharmaceutical TIGER platform which requires many hours for operation, and an 800k$ piece of equipment that fills a room. The Columbia/SNL system could provide a result in 30 minutes, at the cost of a few thousand dollars for the platform, and would be the size of a shoebox or smaller.

  15. Dual-tracer background subtraction approach for fluorescent molecular tomography

    Science.gov (United States)

    Holt, Robert W.; El-Ghussein, Fadi; Davis, Scott C.; Samkoe, Kimberley S.; Gunn, Jason R.; Leblond, Frederic

    2013-01-01

    Abstract. Diffuse fluorescence tomography requires high contrast-to-background ratios to accurately reconstruct inclusions of interest. This is a problem when imaging the uptake of fluorescently labeled molecularly targeted tracers in tissue, which can result in high levels of heterogeneously distributed background uptake. We present a dual-tracer background subtraction approach, wherein signal from the uptake of an untargeted tracer is subtracted from targeted tracer signal prior to image reconstruction, resulting in maps of targeted tracer binding. The approach is demonstrated in simulations, a phantom study, and in a mouse glioma imaging study, demonstrating substantial improvement over conventional and homogenous background subtraction image reconstruction approaches. PMID:23292612

  16. Predicting the statistics of high-energy astrophysical backgrounds

    NARCIS (Netherlands)

    Feyereisen, M.R.

    2017-01-01

    This thesis presents improvements to a methodology for predicting the probability distribution of diffuse isotropic astrophysical backgrounds, applied to high-energy extragalactic gamma rays and neutrinos.

  17. Uncertain Portfolio Selection with Background Risk and Liquidity Constraint

    Directory of Open Access Journals (Sweden)

    Jia Zhai

    2017-01-01

    Full Text Available This paper discusses an uncertain portfolio selection problem with consideration of background risk and asset liquidity. In addition, the transaction costs are also considered. The security returns, background asset return, and asset liquidity are estimated by experienced experts instead of historical data. Regarding them as uncertain variables, a mean-risk model with background risk, liquidity, and transaction costs is proposed for portfolio selection and the crisp forms of the model are provided when security returns obey different uncertainty distributions. Moreover, for better understanding of the impact of background risk and liquidity on portfolio selection, some important theorems are proved. Finally, numerical experiments are presented to illustrate the modeling idea.

  18. Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

    NARCIS (Netherlands)

    Pfister, Frederick; Riedl, Eva; Wang, Qian; vom Hagen, Franziska; Deinzer, Martina; Harmsen, Martin Conrad; Molema, Grietje; Yard, Benito; Feng, Yuxi; Hammes, Hans-Peter

    2011-01-01

    Backgrounds/Aims: Pericyte loss, vasoregression and neuroglial activation are characteristic changes in incipient diabetic retinopathy. In this study, the effect of the antioxidant and antiglycating dipeptide carnosine was studied on the development of experimental diabetic retinopathy.

  19. A strand specific high resolution normalization method for chip-sequencing data employing multiple experimental control measurements

    DEFF Research Database (Denmark)

    Enroth, Stefan; Andersson, Claes; Andersson, Robin

    2012-01-01

    High-throughput sequencing is becoming the standard tool for investigating protein-DNA interactions or epigenetic modifications. However, the data generated will always contain noise due to e.g. repetitive regions or non-specific antibody interactions. The noise will appear in the form of a backg......High-throughput sequencing is becoming the standard tool for investigating protein-DNA interactions or epigenetic modifications. However, the data generated will always contain noise due to e.g. repetitive regions or non-specific antibody interactions. The noise will appear in the form...... of a background distribution of reads that must be taken into account in the downstream analysis, for example when detecting enriched regions (peak-calling). Several reported peak-callers can take experimental measurements of background tag distribution into account when analysing a data set. Unfortunately...

  20. SU-F-T-166: On the Nature of the Background Visible Light Observed in Fiber Optic Dosimetry of Proton Beams

    Energy Technology Data Exchange (ETDEWEB)

    Darafsheh, A; Kassaee, A; Finlay, J [University of Pennsylvania, Philadelphia, PA (United States); Taleei, R [UT Southwestern Medical Center, Dallas, TX (United States)

    2016-06-15

    Purpose: The nature of the background visible light observed during fiber optic dosimetry of proton beams, whether it is due to Cherenkov radiation or not, has been debated in the literature recently. In this work, experimentally and by means of Monte Carlo simulations, we shed light on this problem and investigated the nature of the background visible light observed in fiber optics irradiated with proton beams. Methods: A bare silica fiber optics was embedded in tissue-mimicking phantoms and irradiated with clinical proton beams with energies of 100–225 MeV at Roberts Proton Therapy Center. Luminescence spectroscopy was performed by a CCD-coupled spectrograph to analyze in detail the emission spectrum of the fiber tip across the visible range of 400–700 nm. Monte Carlo simulation was performed by using FLUKA Monte Carlo code to simulate Cherenkov light and ionizing radiation dose deposition in the fiber. Results: The experimental spectra of the irradiated silica fiber shows two distinct peaks at 450 and 650 nm, whose spectral shape is different from that of Cherenkov radiation. We believe that the nature of these peaks are connected to the point defects of silica including oxygen-deficiency center (ODC) and non-bridging oxygen hole center (NBOHC). Monte Carlo simulations confirmed the experimental observations that Cherenkov radiation cannot be solely responsible for such a signal. Conclusion: We showed that Cherenkov radiation is not the dominant visible signal observed in bare fiber optics irradiated with proton beams. We observed two distinct peaks at 450 and 650 nm whose nature is connected with the point defects of silica fiber including oxygen-deficiency center and non-bridging oxygen hole center.

  1. 34 CFR 602.25 - Due process.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 3 2010-07-01 2010-07-01 false Due process. 602.25 Section 602.25 Education... Required Operating Policies and Procedures § 602.25 Due process. The agency must demonstrate that the procedures it uses throughout the accrediting process satisfy due process. The agency meets this requirement...

  2. Action of pentoxifylline on experimental cutaneous leishmaniasis due to Leishmania (Leishmania amazonensis

    Directory of Open Access Journals (Sweden)

    Oliveira Thiago de Sá

    2000-01-01

    Full Text Available In the animal model of leishmaniasis caused by Leishmania (Leishmania amazonensis there is a complex mechanism of the host-parasite interaction. The present study was performed to interfere with the inflammatory reaction to the parasites, through immune modulation. Female C5BL/6 isogenic mice were used, some of which were inoculated on the right ear and others on the right footpad with 3.10(6 stationary phase promastigotes of the MHOM/BR/PH8 strain of L. (L. amazonensis, and were allocated in three groups: the first received pentoxifylline 8mg/kg every 12 h, since the first day; the second one received the same dose since the 40th day of infection and a control group that did not receive any treatment. All the ears excised were analyzed to determine the variation in weight between both ears and for histopathological analyses. A quantification of the parasites was done using the limiting dilution assay. A significant reduction of the number of parasites, was observed among the animals treated which had an accordingly significant reduction on the weight of the ears. Pentoxifylline reduced the macrophages propensity to vacuolation and induced a more effective destruction of the parasites by these cells. Moreover, the group that began the treatment later did not show the same effectiveness.

  3. Evaluation of short-interfering RNAs treatment in experimental rabies due to wild-type virus.

    Science.gov (United States)

    Appolinario, Camila Michele; Allendorf, Susan Dora; Peres, Marina Gea; Fonseca, Clovis Reynaldo; Vicente, Acacia Ferreira; Antunes, João Marcelo Azevedo de Paula; Pantoja, José Carlos Figueiredo; Megid, Jane

    2015-01-01

    We have evaluated the efficacy of short-interfering RNAs targeting the nucleoprotein gene and also the brain immune response in treated and non-treated infected mice. Mice were inoculated with wild-type virus, classified as dog (hv2) or vampire bat (hv3) variants and both groups were treated or left as controls. No difference was observed in the lethality rate between treated and non-treated groups, although clinical evaluation of hv2 infected mice showed differences in the severity of clinical disease (p=0.0006). Evaluation of brain immune response 5 days post-inoculation in treated hv2 group showed no difference among the analyzed genes, whereas after 10 days post-inoculation there was increased expression of 2',5'-oligoadenylate synthetase 1, tumor necrosis factor alpha, interleukin 12, interferon gamma, and C-X-C motif chemokine 10 associated with higher expression of N gene in the same period (prabies treatment. Copyright © 2015 Elsevier Editora Ltda. All rights reserved.

  4. Is experimental motion blindness due to sensory suppression? An ERP approach.

    Science.gov (United States)

    Niedeggen, Michael; Sahraie, Arash; Hesselmann, Guido; Milders, Maarten; Blakemore, Colin

    2002-04-01

    Recent psychophysical studies have revealed attentional modulation of visual motion perception and interest now focuses on the locus of this interaction. Using event-related brain potentials (ERPs) we examined whether transient motion blindness evoked in a dual task [Vision Res. 41 (2001) 1613-1617] is related to a selection process occurring at the stage of sensory processing or at a higher level. In our paradigm, a particular change of colour of the fixation point cued the subject to detect a brief episode of coherent random dot motion embedded in a succession of episodes of incoherent motion. Detection of the coherent motion was significantly impaired when it occurred simultaneously with the colour cue, and recovered over the subsequent 300 ms. This functional relationship was reflected in the amplitude of a sensory, motion-evoked component (N200), and in a late positive complex (P300). However, a direct comparison of ERPs produced by stimuli that were detected or missed revealed differences only in the P300 component. These results indicate that attenuation of sensory motion processing does not account for this transient, attention-induced deficit in visual motion perception. Copyright 2002 Elsevier Science B.V.

  5. Evaluation of short-interfering RNAs treatment in experimental rabies due to wild-type virus

    Directory of Open Access Journals (Sweden)

    Camila Michele Appolinario

    2015-09-01

    Full Text Available We have evaluated the efficacy of short-interfering RNAs targeting the nucleoprotein gene and also the brain immune response in treated and non-treated infected mice. Mice were inoculated with wild-type virus, classified as dog (hv2 or vampire bat (hv3 variants and both groups were treated or leaved as controls. No difference was observed in the lethality rate between treated and non-treated groups, although clinical evaluation of hv2 infected mice showed differences in the severity of clinical disease (p = 0.0006. Evaluation of brain immune response 5 days post-inoculation in treated hv2 group showed no difference among the analyzed genes, whereas after 10 days post-inoculation there was increased expression of 2′,5′-oligoadenylate synthetase 1, tumor necrosis factor alpha, interleukin 12, interferon gamma, and C-X-C motif chemokine 10 associated with higher expression of N gene in the same period (p < 0.0001. In hv2 non-treated group only higher interferon beta expression was found at day 5. The observed differences in results of the immune response genes between treated and non-treated groups is not promising as they had neither impact on mortality nor even a reduction in the expression of N gene in siRNA treated animals. This finding suggests that the use of pre-designed siRNA alone may not be useful in rabies treatment.

  6. [Experimental study of immune reactivity in Swiss mice due to topical administration of three textile dyes].

    Science.gov (United States)

    Gavăt, C C; Lupuşoru, R V; Ghiciuc, Cristina Mihaela; Lupuşoru, Cătălina Elena

    2010-01-01

    Reactive Red 183, Reactive Red 2 and Reactive Blue 204 (red dye, green dye and blue dye) are three reactive dyes frequently used in textile industry. In some atmospheric conditions ( high temperature, perspiration, pH values, UV/IR radiations), some quantities of these hydrolyzed dyes, could pass from textile clothes directly into the human skin. There were used 4 groups of white Swiss mice (with similar weight and number of both sexes), control group and 3 groups, treated once daily with a retro-auricular application of different reactive dyes. After 14 days of treatment, blood samples were taken from retro-orbitary plexus to assess leukocyte count, phagocytic capacity of peripheral neutrophils, serum opsonic capacity, phagocyte capacity and bactericidal capacity of peritoneal macrophages, splenic T lymphocytes with rossetting capacity and spleen cells forming Jerne plaques. The retro-acuricular and latero-cervical nodes were weighted. Red dye did not influence the weight of the studied nodes, but determined statistically significant modifications on non-specific immune system parameters. Blue and grena dyes determined modifications of weight especially of retroauricular nodes. Grena dye determined important effects of non-specific immune system parameters (serum opsonic capacity, phagocyte capacity and bactericidal capacity of peritoneal macrophages). The blue dye did not determine a biological response. Red and green dye determined important effects on non-specific immune system parameters.

  7. Role of the quorum-sensing system in experimental pneumonia due to Pseudomonas aeruginosa in rats.

    Science.gov (United States)

    Lesprit, Philippe; Faurisson, Francois; Join-Lambert, Olivier; Roudot-Thoraval, Francoise; Foglino, Maryline; Vissuzaine, Christiane; Carbon, Claude

    2003-06-01

    The virulence of Pseudomonas aeruginosa is partly controlled by the las quorum-sensing system. A rat model of acute pneumonia was used to investigate the pathophysiological impact of this system by comparing the virulence of the wild-type virulent laboratory strain PAO1 with that of its lasR-deleted mutant PAOR. In comparison with PAO1, PAOR was avirulent after an instillation of 106 cfu (mortality rates, 72 versus 0%, respectively; p < 0.0001). A ten-fold higher inoculum slightly increased the mortality rate induced by PAOR (25%), which remained lower than that induced by PAO1 (75%, p = 0.0001). In addition, with both inocula lung and bronchoalveolar lavage bacterial counts were significantly lower in rats infected with PAOR than with PAO1 (p

  8. Synergic effect of combination of glycyrol and fluconazole against experimental cutaneous candidiasis due to Candida albicans.

    Science.gov (United States)

    Rhew, Zheong-Imm; Han, Yongmoon

    2016-10-01

    In this study, we investigated the anti-fungal activity of glycyrol, a coumarine isolated from licorice (Glycyrrhizae Radix), in a murine model of cutaneous candidiasis caused by Candida albicans. Compared to the infected sites, located on the mice's back, of the untreated control mice, the infected sites treated with glycyrol had reduced CFU (colony forming unit) values up to 60 and 85.5 % at 20 and 40 μg/mouse of glycyrol, respectively (P fluconazole (10 μg/mouse), demonstrating that the combination therapy is approximately 4 times more effective than fluconazole alone at 20 μg/mouse (P fluconazole alone at 40 μg/mouse (P fluconazole invade C. albicans more readily and attack fluconazole's target in the fungus membrane. In summary, our data indicate that glycyrol may contribute to the development of a novel agent that possesses antifungal activity against cutaneous candidiasis.

  9. An Integrated Experimental and Computational Study of Heating due to Surface Catalysis under Hypersonic Conditions

    Science.gov (United States)

    2012-08-01

    platform COOLFluiD (Computational Object Oriented Libraries for Fluid Dynamics) [1, 2, 3, 4] is VKI collaborative software environment for high...Poedts. The COOLFluiD framework: Design solutions for high-performance object oriented scientific computing software . In P. M. A. Sloot V. S. Sunderan, G...Andrea Lani. An Object Oriented and high performance platform for aerothermodynamics simulation. PhD thesis, Université Libre de Bruxelles, Chaussée

  10. Early pathogenesis and inflammatory response in experimental bovine mastitis due to Streptococcus uberis

    DEFF Research Database (Denmark)

    Pedersen, L.H.; Aalbæk, B.; Røntved, C.M.

    2003-01-01

    and neutrophils) and within the lumen of ducts and alveoli. Lesions developed progressively in an ascending manner and became widespread throughout the mammary gland in less than 8 h. The parallel development of inflammation and increased concentrations of SAA and haptoglobin in milk points to these acute phase...

  11. Experimental Structural Dynamic Response of Plate Specimens Due to Sonic Loads in a Progressive Wave Tube

    Science.gov (United States)

    Betts, Juan F.

    2001-01-01

    The objective of the current study was to assess the repeatability of experiments at NASA Langley's Thermal Acoustic Fatigue Apparatus (TAFA) facility and to use these experiments to validate numerical models. Experiments show that power spectral density (PSD) curves were repeatable except at the resonant frequencies, which tended to vary between 5 Hz to 15 Hz. Results show that the thinner specimen had more variability in the resonant frequency location than the thicker sample, especially for modes higher than the first mode in the frequency range. Root Mean Square (RMS) tended to be more repeatable. The RMS behaved linearly through the SPL range of 135 to 153 dB. Standard Deviations (STDs) of the results tended to be relatively low constant up to about 147 dB. The RMS results were more repeatable than the PDS results. The STD results were less than 10% of the RMS results for both the 0.125 in (0.318 cm) and 0.062 in (0.1588 cm) thick plate. The STD of the PSD results were around 20% to 100% of the mean PSD results for non-resonant and resonant frequencies, respectively, for the 0.125 in (0.318 cm) thicker plate and between 25% to 125% of the mean PSD results, for nonresonant and resonant frequencies, respectively, for the thinner plate.

  12. Improvement of LOD in Fluorescence Detection with Spectrally Nonuniform Background by Optimization of Emission Filtering.

    Science.gov (United States)

    Galievsky, Victor A; Stasheuski, Alexander S; Krylov, Sergey N

    2017-10-17

    The limit-of-detection (LOD) in analytical instruments with fluorescence detection can be improved by reducing noise of optical background. Efficiently reducing optical background noise in systems with spectrally nonuniform background requires complex optimization of an emission filter-the main element of spectral filtration. Here, we introduce a filter-optimization method, which utilizes an expression for the signal-to-noise ratio (SNR) as a function of (i) all noise components (dark, shot, and flicker), (ii) emission spectrum of the analyte, (iii) emission spectrum of the optical background, and (iv) transmittance spectrum of the emission filter. In essence, the noise components and the emission spectra are determined experimentally and substituted into the expression. This leaves a single variable-the transmittance spectrum of the filter-which is optimized numerically by maximizing SNR. Maximizing SNR provides an accurate way of filter optimization, while a previously used approach based on maximizing a signal-to-background ratio (SBR) is the approximation that can lead to much poorer LOD specifically in detection of fluorescently labeled biomolecules. The proposed filter-optimization method will be an indispensable tool for developing new and improving existing fluorescence-detection systems aiming at ultimately low LOD.

  13. Predictors of Recurrent Sickness Absence Due to Depressive Disorders - A Delphi Approach Involving Scientists and Physicians

    NARCIS (Netherlands)

    Norder, G.; Roelen, C.A.M.; van Rhenen, W.; Buitenhuis, J.; Bultmann, U.; Anema, J.R.

    2012-01-01

    Background: Depression is a common and highly recurrent mental disorder that is accompanied by poor functioning at home and at work. Not all depressed employees report sick and little is known about variables associated with sickness absence (SA) due to depression. Recurrent SA due to depression

  14. Background identification and suppression for the measurement of (n,{gamma}) reactions with the DANCE array at LANSCE

    Energy Technology Data Exchange (ETDEWEB)

    Reifarth, R. E-mail: reifarth@lanl.gov; Bredeweg, T.A.; Alpizar-Vicente, A.; Browne, J.C.; Esch, E.-I.; Greife, U.; Haight, R.C.; Hatarik, R.; Kronenberg, A.; O' Donnell, J.M.; Rundberg, R.S.; Ullmann, J.L.; Vieira, D.J.; Wilhelmy, J.B.; Wouters, J.M

    2004-10-01

    In the commissioning phase of the DANCE project (Detector for Advanced Neutron Capture Experiments) measurements have been performed with special emphasis on the identification and suppression of possible backgrounds for the planned (n,{gamma}) experiments. This report describes several background sources, observed in the experiment or anticipated from simulations, which will need to be suppressed in this and in similar detectors that are planned at other facilities. First successes are documented in the suppression of background from scattered neutrons captured in the detector as well as from the internal radiation. Experimental results and simulations using the GEANT code are compared.

  15. Production lost due to cervical cancer in Poland in 2012

    Directory of Open Access Journals (Sweden)

    Katarzyna Dubas-Jakóbczyk

    2016-06-01

    Full Text Available Background: Poland has one of the highest cervical cancer mortality rates in Europe. It is related to the problem of late diagnosis and low attendance rate in screening programs. The objective of the study has been to assess the annual production loss due to the cervical cancer morbidity and mortality in Poland in 2012. The outcomes have been to provide comprehensive information on cervical cancer’s influence on population’s ability to work and its overall economic burden for the society. The study has also provided the methodological framework for disease-related production losses in Polish settings. Material and Methods: The human capital method was used. The production losses were calculated in both monetary and quantitative terms (working days lost due to 4 following reasons: 1 temporary disability to work, 2 permanent disability, 3 informal care, and 4 mortality. Results: Cervical cancer resulted in approx. 702 964 working days lost in 2012 due to absence at work for both patients and care givers and a total number of 957 678 working days lost due to patients’ mortality. The total value of production lost was assessed at 111.4 million euros. More than 66% of this value was attributed to women’s mortality. Conclusions: The calculation of production lost due to cervical cancer burden provides strong evidence to support adequate health promotion and disease prevention actions. Actions promoting cervical cancer screening should be intensified including workplace health promotion activities. Med Pr 2016;67(3:289–299

  16. HIRENASD Experimental Data

    Data.gov (United States)

    National Aeronautics and Space Administration — Experimental Data for HIRENASD configuration Zip files below contain the experimental data for the pressure coefficients, both the static and the forced oscillation...

  17. Background Music in Educational Games: Motivational Appeal and Cognitive Impact

    Science.gov (United States)

    Linek, Stephanie B.; Marte, Birgit; Albert, Dietrich

    2011-01-01

    Most game-designers likely stick to the assumption that background music is a design feature for fostering fun and game play. From a psychological point of view, these (intuitive) aspects act upon the intrinsic motivation and the flow experience of players. However, from a pure cognitive perspective on instructional design, background music could…

  18. White Letters on Colored Backgrounds: Legibility and Preference.

    Science.gov (United States)

    Pett, Dennis

    This paper reviews two studies of color preference and the relationships between color and legibility. The Gustin study in 1991 dealt with the legibility of and preference for projected slides with colored backgrounds and white text. The order of background color preference was cyan, blue, green, yellow, magenta, and red. The follow-up study by…

  19. Linear model for fast background subtraction in oligonucleotide microarrays

    NARCIS (Netherlands)

    Kroll, K.M.; Barkema, G.T.; Carlon, E.

    2009-01-01

    Background One important preprocessing step in the analysis of microarray data is background subtraction. In high-density oligonucleotide arrays this is recognized as a crucial step for the global performance of the data analysis from raw intensities to expression values. Results We propose here an

  20. Using Music as a Background for Reading: An Exploratory Study.

    Science.gov (United States)

    Mulliken, Colleen N.; Henk, William A.

    1985-01-01

    Reports on a study during which intermediate level students were exposed to three auditory backgrounds while reading (no music, classical music, and rock music), and their subsequent comprehension performance was measured. Concludes that the auditory background during reading may affect comprehension and that, for most students, rock music should…