WorldWideScience

Sample records for experiences initiating software

  1. EXPERIENCES INITIATING SOFTWARE PRODUCT LINE ENGINEERING IN SMALL TEAMS WITH PULSE

    DEFF Research Database (Denmark)

    Mærsk-Møller, Hans Martin; Jørgensen, Bo Nørregaard

    2010-01-01

    papers and collective results on Software Product Line Engineering (SPLE) in the context of small teams. This paper remedies this situation by providing experiences from a successful approach of applying software product line engineering in a small team. We conduct a transition from single......Small teams of software engineers are represented both in small companies and semi-independent fractions in medium and large companies. Even though some results and experience papers have been published in the context of Small- and Medium-Sized Enterprises (SMEs), there is a lack of experience......-system production to Software Product Line (SPL) in the domain of greenhouse climate control systems. The domain contains inherent variabilities and extensive commonalities between the products in scope, which makes it a prime candidate for SPLE - besides having good business prospects. The transitioning to SPLE...

  2. Accuracy and initial clinical experience with measurement software (advanced vessel analysis) in three-dimensional imaging

    Energy Technology Data Exchange (ETDEWEB)

    Abe, Toshi; Hirohata, Masaru [Kurume Univ., Fukuoka (Japan). School of Medicine; Tanigawa, Hitoshi [Kurume Univ., Fukuoka (Japan). Hospital] [and others

    2002-12-01

    Recently, the clinical benefits of three dimensional (3D) imaging, such as 3D-CTA and 3D-DSA, in cerebro-vascular disease have been widely recognized. Software for quantitative analysis of vascular structure in 3D imaging (advanced vessel analysis: AVA) has been developed. We evaluated AVA with both phantom studies and a few clinical cases. In spiral and curvy aluminum tube phantom studies, the accuracy of diameter measurements was good in 3D images produced from data set generated by multi-detector row CT or rotational angiography. The measurement error was less than 0.03 mm on aluminum tube phantoms that were 3 mm and 5 mm in diameter. In the clinical studies, the differences of carotid artery diameter measurements between 2D-DSA and 3D-DSA was less than 0.3 mm in. The measurement of length, diameter and angle by AVA should provide useful information for planning surgical and endovascular treatments of cerebro-vascular disease. (author)

  3. Innovation Initiatives in Large Software Companies

    DEFF Research Database (Denmark)

    Edison, Henry; Wang, Xiaofeng; Jabangwe, Ronald

    2018-01-01

    can potentially lower their agility to innovate. Objective:The aims of this study are to provide an overview of the current research on innovation initiatives and to identify the challenges of implementing those initiatives in the context of large software companies. Method: The investigation...... was primarily performed using a systematic mapping approach of published literature on corporate innovation and entrepreneurship, which was then complemented with interviews with four experts with rich industry experience. Results: Our mapping study results suggest that, there is a lack of high quality...... empirical studies on innovation initiative in the context of large software companies. A total of 7 studies are conducted in the context of large software companies, which reported 5 types of initiatives: intrapreneurship, bootlegging, internal venture, spin-off and crowdsourcing. Our study offers three...

  4. Detailed review and analysis of complex radiotherapy clinical trial planning data: evaluation and initial experience with the SWAN software system.

    Science.gov (United States)

    Ebert, Martin A; Haworth, Annette; Kearvell, Rachel; Hooton, Ben; Coleman, Rhonda; Spry, Nigel; Bydder, Sean; Joseph, David

    2008-02-01

    Contemporary radiotherapy clinical trials typically require complex three-dimensional (3D) treatment planning. This produces large amounts of data relating technique and dose delivery for correlation with patient outcomes. Assessment of the quality of this information is required to ensure protocol compliance, to quantify the variation in treatments given to patients and to enhance the power of studies to determine correlates of patient outcomes. A software system ('SWAN') was developed to facilitate the objective analysis, quality-assurance and review of digital treatment planning data from multi-centre radiotherapy trials. The utility of this system was assessed on the basis of its functionality and our experience of its use in the context of multi-centre clinical trials and trials-support activities. The SWAN system has been shown to have the functionality required for use in several multi-centre trials, including automated review and archive processes. Approximately 800 treatment plans from over 30 participating institutions have so far been assessed with the system for several treatment planning scenarios. To illustrate this we include a description of the use of the system for a large-recruitment prostate radiotherapy trial being undertaken in Australasia, including examples of how the review process has changed clinical practice. The successful implementation of SWAN has been demonstrated in a number of clinical trials. The software provides an opportunity for comprehensive review of treatment parameters that could impact on clinical outcomes and trial results. Such quality-assurance (QA) has previously been difficult or impossible to achieve, particularly for a clinical trial involving large numbers of patients. Such reviews have highlighted inconsistencies in clinical practice that have since been addressed through feedback from the review process. The process of data collection and review should be undertaken by dedicated, experienced and skilled staff in

  5. Initial Cooling Experiment (ICE)

    CERN Multimedia

    Photographic Service; CERN PhotoLab

    1978-01-01

    In 1977, in a record-time of 9 months, the magnets of the g-2 experiment were modified and used to build a proton/antiproton storage ring: the "Initial Cooling Experiment" (ICE). It served for the verification of the cooling methods to be used for the "Antiproton Project". Stochastic cooling was proven the same year, electron cooling followed later. Also, with ICE the experimental lower limit for the antiproton lifetime was raised by 9 orders of magnitude: from 2 microseconds to 32 hours. For its previous life as g-2 storage ring, see 7405430. More on ICE: 7711282, 7809081, 7908242.

  6. The Software Engineering Laboratory: An operational software experience factory

    Science.gov (United States)

    Basili, Victor R.; Caldiera, Gianluigi; Mcgarry, Frank; Pajerski, Rose; Page, Gerald; Waligora, Sharon

    1992-01-01

    For 15 years, the Software Engineering Laboratory (SEL) has been carrying out studies and experiments for the purpose of understanding, assessing, and improving software and software processes within a production software development environment at NASA/GSFC. The SEL comprises three major organizations: (1) NASA/GSFC, Flight Dynamics Division; (2) University of Maryland, Department of Computer Science; and (3) Computer Sciences Corporation, Flight Dynamics Technology Group. These organizations have jointly carried out several hundred software studies, producing hundreds of reports, papers, and documents, all of which describe some aspect of the software engineering technology that was analyzed in the flight dynamics environment at NASA. The studies range from small, controlled experiments (such as analyzing the effectiveness of code reading versus that of functional testing) to large, multiple project studies (such as assessing the impacts of Ada on a production environment). The organization's driving goal is to improve the software process continually, so that sustained improvement may be observed in the resulting products. This paper discusses the SEL as a functioning example of an operational software experience factory and summarizes the characteristics of and major lessons learned from 15 years of SEL operations.

  7. Software Acquisition Management Practical Experience

    Science.gov (United States)

    2009-04-23

    Washington, D.C., 2002 FAA 1995 FAA Type Certification Process, March 2, 1995 http://www.airweb.faa.gov/Regulatory_and_Guidance_Library/ rgO rders.nsf/0...matter expert for several FAA NAS Plan Modernization Programs and provided a deposition for contract termination. Mr. Jones served as the Software

  8. Initial Egyptian ECMO experience

    Directory of Open Access Journals (Sweden)

    Akram Abdelbary

    2016-04-01

    Results: A total of twelve patients received ECMO between January 2014 and June 2015. The mean age was 35.9 years. (range 13–65 years, 8 males, with VV ECMO in 10 patients, and VA ECMO in 2 patients. Out of ten patients of VV ECMO, one had H1N1 pneumonia, one had advanced vasculitic lung, four had bacterial pneumonia, two traumatic lung contusions and one with organophosphorus poisoning, and one undiagnosed etiology leading to severe ARDS. Lung injury score range was 3–3.8, PaO2/FiO2 (20–76 mechanical ventilation duration before ECMO 1–14 days, Femoro-jugular cannulation in 7 patients and femoro-femoral in 2 patients and femoro-subclavian in 1 patient; all patients were initially sedated and paralyzed for (2–4 days and ventilated on pressure controlled ventilation with Pmax of 25 cm H2O and PEEP of 10 cm H2O. In VA ECMO patients were cannulated percutaneously using femoro-femoral approach. One patient showed no neurologic recovery and died after 24 h, the other had CABG on ECMO however the heart didn’t recover and died after 9 days. Heparin intravenous infusion was used initially in all patients and changed to Bivalirudin in 2 patients due to possible HIT. Pump flow ranged from 2.6 to 6.5 L/min. Average support time was 12 days (range 2–24 days. Seven patients (63.3% were successfully separated from ECMO and survived to hospital discharge. Hospital length of stay ranged from 3 to 42 days, tracheostomy was done percutaneously in 5 patients and surgically in 3. Gastrointestinal bleeding occurred in 6 patients, VAP in 7 patients, neurologic complications in 1 patient with complete recovery, cardiac arrhythmias in 3 patients, pneumothorax in 9 patients, and deep venous thrombosis in 2 patients.

  9. Signal processing with free software practical experiments

    CERN Document Server

    Auger, François

    2014-01-01

    An ideal resource for students, industrial engineers, and researchers, Signal Processing with Free Software Practical Experiments presents practical experiments in signal processing using free software. The text introduces elementary signals through elementary waveform, signal storage files and elementary operations on signals and then presents the first tools to signal analysis such as temporal and frequency characteristics leading to Time-frequency analysis. Non-parametric spectral analysis is also discussed as well as signal processing through sampling, resampling, quantification, an

  10. INITIAL COOLING EXPERIMENT (ICE)

    CERN Multimedia

    CERN PhotoLab

    1979-01-01

    ICE was built in 1977, using the modified bending magnets of the g-2 muon storage ring (see 7405430). Its purpose was to verify the validity of stochastic and electron cooling for the antiproton project. Stochastic cooling proved a resounding success early in 1978 and the antiproton project could go ahead, now entirely based on stochastic cooling. Electron cooling was experimented with in 1979. The 26 kV equipment is housed in the cage to the left of the picture, adjacent to the "e-cooler" located in a straight section of the ring. With some modifications, the cooler was later transplanted into LEAR (Low Energy Antiproton Ring) and then, with further modifications, into the AD (Antiproton Decelerator), where it cools antiprotons to this day (2006). See also: 7711282, 7802099, 7809081.

  11. EXPERIENCES WITH IDEA PROMOTING INITIATIVES

    DEFF Research Database (Denmark)

    Gish, Liv

    2011-01-01

    with a growing interest. In this paper I examine three different idea promoting initiatives carried out in Grundfos, a leading pump manufacturer. In the analysis I address what understandings of idea work are inscribed in the initiatives and what role these initiatives play in the organization with respect......In new product development a central activity is to provide new ideas. Over the last decades experiences with stimulating employee creativity and establishing idea promoting initiatives have been made in industrial practice. Such initiatives are often labeled Idea Management – a research field...... to idea work. Furthermore I look into what makes these initiatives ‘work’ or ‘not work’. The analysis builds on an in-depth case study made in Grundfos based on 40 interviews with R&D professionals and managers. The managerial implications of the study are that managers should be aware of what...

  12. Offline software for the DAMPE experiment

    Science.gov (United States)

    Wang, Chi; Liu, Dong; Wei, Yifeng; Zhang, Zhiyong; Zhang, Yunlong; Wang, Xiaolian; Xu, Zizong; Huang, Guangshun; Tykhonov, Andrii; Wu, Xin; Zang, Jingjing; Liu, Yang; Jiang, Wei; Wen, Sicheng; Wu, Jian; Chang, Jin

    2017-10-01

    A software system has been developed for the DArk Matter Particle Explorer (DAMPE) mission, a satellite-based experiment. The DAMPE software is mainly written in C++ and steered using a Python script. This article presents an overview of the DAMPE offline software, including the major architecture design and specific implementation for simulation, calibration and reconstruction. The whole system has been successfully applied to DAMPE data analysis. Some results obtained using the system, from simulation and beam test experiments, are presented. Supported by Chinese 973 Program (2010CB833002), the Strategic Priority Research Program on Space Science of the Chinese Academy of Science (CAS) (XDA04040202-4), the Joint Research Fund in Astronomy under cooperative agreement between the National Natural Science Foundation of China (NSFC) and CAS (U1531126) and 100 Talents Program of the Chinese Academy of Science

  13. The Muon Ionization Cooling Experiment User Software

    Science.gov (United States)

    Dobbs, A.; Rajaram, D.; MICE Collaboration

    2017-10-01

    The Muon Ionization Cooling Experiment (MICE) is a proof-of-principle experiment designed to demonstrate muon ionization cooling for the first time. MICE is currently on Step IV of its data taking programme, where transverse emittance reduction will be demonstrated. The MICE Analysis User Software (MAUS) is the reconstruction, simulation and analysis framework for the MICE experiment. MAUS is used for both offline data analysis and fast online data reconstruction and visualization to serve MICE data taking. This paper provides an introduction to MAUS, describing the central Python and C++ based framework, the data structure and and the code management and testing procedures.

  14. Software-Based Student Response Systems: An Interdisciplinary Initiative

    Science.gov (United States)

    Fischer, Carol M.; Hoffman, Michael S.; Casey, Nancy C.; Cox, Maureen P.

    2015-01-01

    Colleagues from information technology and three academic departments collaborated on an instructional technology initiative to employ student response systems in classes in mathematics, accounting and education. The instructors assessed the viability of using software-based systems to enable students to use their own devices (cell phones,…

  15. Experiences with Software Quality Metrics in the EMI middlewate

    OpenAIRE

    Alandes, M; Kenny, E M; Meneses, D; Pucciani, G

    2012-01-01

    The EMI Quality Model has been created to define, and later review, the EMI (European Middleware Initiative) software product and process quality. A quality model is based on a set of software quality metrics and helps to set clear and measurable quality goals for software products and processes. The EMI Quality Model follows the ISO/IEC 9126 Software Engineering – Product Quality to identify a set of characteristics that need to be present in the EMI software. For each software characteristi...

  16. The CALICE Software Framework and Operational Experience

    CERN Document Server

    Terwort, Mark

    2010-01-01

    The CALICE collaboration is developing calorimeters for a future linear collider, and has collected a large amount of physics data during test beam efforts. For the analysis of these data, standard software available for linear collider detector studies is applied. This software provides reconstruction of raw data, simulation, digitization and data management, which is based on grid tools. The data format for analysis is compatible with the general linear collider software. Moreover, existing frameworks such as Marlin are employed for the CALICE software needs. The structure and features of the software framework are reported here as well as results from the application of this software to test beam data.

  17. Software Development Initiatives to Identify and Mitigate Security Threats - Two Systematic Mapping Studies

    Directory of Open Access Journals (Sweden)

    Paulina Silva

    2016-12-01

    Full Text Available Software Security and development experts have addressed the problem of building secure software systems. There are several processes and initiatives to achieve secure software systems. However, most of these lack empirical evidence of its application and impact in building secure software systems. Two systematic mapping studies (SM have been conducted to cover the existent initiatives for identification and mitigation of security threats. The SMs created were executed in two steps, first in 2015 July, and complemented through a backward snowballing in 2016 July. Integrated results of these two SM studies show a total of 30 relevant sources were identified; 17 different initiatives covering threats identification and 14 covering the mitigation of threats were found. All the initiatives were associated to at least one activity of the Software Development Lifecycle (SDLC; while 6 showed signs of being applied in industrial settings, only 3 initiatives presented experimental evidence of its results through controlled experiments, some of the other selected studies presented case studies or proposals.

  18. Software Acquisition Best Practices: Experiences From the Space Systems Domain

    National Research Council Canada - National Science Library

    Adams, R

    2004-01-01

    This report describes a comprehensive set of software acquisition best practices that the Software Acquisition MOlE research team has identified based on their experience with numerous space programs over many years...

  19. Initial experience with the CDF SVT trigger

    CERN Document Server

    Ashmanskas, B; Bardi, A; Bari, M; Baumgart, M; Belforte, S; Berryhill, J W; Bogdan, M; Carosi, R; Cerri, A; Chlachidze, G; Culberston, R; Dell'Orso, Mauro; Donati, S; Fiori, I; Frisch, H; Galeotti, S; Giannetti, P; Glagolev, V; Léger, A; Liu, Y; Meschi, E; Moneta, L; Morsani, F; Nakaya, T; Punzi, G; Rescigno, M; Ristori, L; Sanders, H; Sarkar, S; Semenov, A; Shochet, M; Speer, T; Spinella, F; Vataga, H; Wu, X; Yang, U; Zanello, L; Zanetti, A M

    2003-01-01

    The Collider Detector at Fermilab (CDF) Silicon Vertex Tracker (SVT) is a device that works inside the CDF Level 2 trigger to find and fit tracks in real time using the central silicon vertex detector information. SVT starts from tracks found by the Level 1 central chamber fast trigger and adds the silicon information to compute transverse track parameters with offline quality in about 15 mu s. The CDF SVT is fully installed and functional and has been exercised with real data during the spring and summer 2001. It is a complex digital device of more than 100 VME boards that performs a dramatic data reduction (only about one event in a thousand is accepted by the trigger). Diagnosing rare failures poses a special challenge and SVT internal data flow is monitored by dedicated hardware and software. This paper briefly covers the SVT architecture and design and reports on the SVT building/commissioning experience (hardware and software) and on the first results from the initial running.

  20. Initial experience with the CDF SVT trigger

    Science.gov (United States)

    Ashmanskas, B.; Barchiesi, A.; Bardi, A.; Bari, M.; Baumgart, M.; Belforte, Stefano; Berryhill, J.; Bogdan, M.; Carosi, R.; Cerri, A.; Chlachidze, G.; Culberston, R.; Dell'Orso, M.; Donati, S.; Fiori, I.; Frisch, H.; Galeotti, S.; Giannetti, P.; Glagolev, V.; Leger, A.; Liu, Y.; Meschi, E.; Moneta, L.; Morsani, F.; Nakaya, T.; Punzi, G.; Rescigno, M.; Ristori, L.; Sanders, H.; Sarkar, S.; Semenov, A.; Shochet, M.; Speer, T.; Spinella, F.; Vataga, H.; Wu, X.; Yang, U.; Zanello, L.; Zanetti, A. M.

    2003-03-01

    The Collider Detector at Fermilab (CDF) Silicon Vertex Tracker (SVT) is a device that works inside the CDF Level 2 trigger to find and fit tracks in real time using the central silicon vertex detector information. SVT starts from tracks found by the Level 1 central chamber fast trigger and adds the silicon information to compute transverse track parameters with offline quality in about 15 μs. The CDF SVT is fully installed and functional and has been exercised with real data during the spring and summer 2001. It is a complex digital device of more than 100 VME boards that performs a dramatic data reduction (only about one event in a thousand is accepted by the trigger). Diagnosing rare failures poses a special challenge and SVT internal data flow is monitored by dedicated hardware and software. This paper briefly covers the SVT architecture and design and reports on the SVT building/commissioning experience (hardware and software) and on the first results from the initial running.

  1. Experiences with Software Quality Metrics in the EMI Middleware

    OpenAIRE

    Alandes, Maria

    2012-01-01

    PUBLISHED he EMI Quality Model has been created to define, and later review, the EMI (European Middleware Initiative) software product and process quality. A quality model is based on a set of software quality metrics and helps to set clear and measurable quality goals for software products and processes. The EMI Quality Model follows the ISO/IEC 9126 Software Engineering – Product Quality to identify a set of characteris...

  2. Application of QC_DR software for acceptance testing and routine quality control of direct digital radiography systems: initial experiences using the Italian Association of Physicist in Medicine quality control protocol.

    Science.gov (United States)

    Nitrosi, Andrea; Bertolini, Marco; Borasi, Giovanni; Botti, Andrea; Barani, Adriana; Rivetti, Stefano; Pierotti, Luisa

    2009-12-01

    Ideally, medical x-ray imaging systems should be designed to deliver maximum image quality at an acceptable radiation risk to the patient. Quality assurance procedures are employed to ensure that these standards are maintained. A quality control protocol for direct digital radiography (DDR) systems is described and discussed. Software to automatically process and analyze the required images was developed. In this paper, the initial results obtained on equipment of different DDR manufacturers were reported. The protocol was developed to highlight even small discrepancies in standard operating performance.

  3. GIMS-Software for asset market experiments.

    Science.gov (United States)

    Palan, Stefan

    2015-03-01

    In this article we lay out requirements for an experimental market software for financial and economic research. We then discuss existing solutions. Finally, we introduce GIMS, an open source market software which is characterized by extensibility and ease of use, while offering nearly all of the required functionality.

  4. GIMS—Software for asset market experiments

    Science.gov (United States)

    Palan, Stefan

    2015-01-01

    In this article we lay out requirements for an experimental market software for financial and economic research. We then discuss existing solutions. Finally, we introduce GIMS, an open source market software which is characterized by extensibility and ease of use, while offering nearly all of the required functionality. PMID:26525085

  5. Continuous software quality analysis for the ATLAS experiment

    CERN Document Server

    Washbrook, Andrew; The ATLAS collaboration

    2017-01-01

    The software for the ATLAS experiment on the Large Hadron Collider at CERN has evolved over many years to meet the demands of Monte Carlo simulation, particle detector reconstruction and data analysis. At present over 3.8 million lines of C++ code (and close to 6 million total lines of code) are maintained by an active worldwide developer community. In order to run the experiment software efficiently at hundreds of computing centres it is essential to maintain a high level of software quality standards. The methods proposed to improve software quality practices by incorporating checks into the new ATLAS software build infrastructure.

  6. An Experiment in Microtask Crowdsourcing Software Design

    OpenAIRE

    Lopez, Consuelo

    2015-01-01

    Microtask crowdsourcing is a form of crowdsourcing in which work is decomposed into a set of small, self-contained tasks, which each can typically be completed in a matter of minutes. The approach has been used to address a number of different problems, ranging from labeling images to planning travel. To date, however, little is known about the potential of microtask crowdsourcing in software engineering. This thesis explores microtask crowdsourcing as applied to software design work. We par...

  7. Robonaut Mobile Autonomy: Initial Experiments

    Science.gov (United States)

    Diftler, M. A.; Ambrose, R. O.; Goza, S. M.; Tyree, K. S.; Huber, E. L.

    2006-01-01

    A mobile version of the NASA/DARPA Robonaut humanoid recently completed initial autonomy trials working directly with humans in cluttered environments. This compact robot combines the upper body of the Robonaut system with a Segway Robotic Mobility Platform yielding a dexterous, maneuverable humanoid ideal for interacting with human co-workers in a range of environments. This system uses stereovision to locate human teammates and tools and a navigation system that uses laser range and vision data to follow humans while avoiding obstacles. Tactile sensors provide information to grasping algorithms for efficient tool exchanges. The autonomous architecture utilizes these pre-programmed skills to form complex behaviors. The initial behavior demonstrates a robust capability to assist a human by acquiring a tool from a remotely located individual and then following the human in a cluttered environment with the tool for future use.

  8. Experiences with Architectural Software Configuration Management in Ragnarok

    DEFF Research Database (Denmark)

    Christensen, Henrik Bærbak

    1998-01-01

    This paper describes a model, denoted architectural software configuration management, that minimises the gap between software design and configuration management by allowing developers to do configuration- and version control of the abstractions and hierarchy in a software architecture. The model...... emphasises traceability and reproducibility by unifying the concepts version and bound configuration. Experiences with such a model, implemented in a prototype “Ragnarok”, from three real-life, small- to medium-sized, software development projects are reported. The conclusion is that the presented model...... is viable and “feels natural ” for software developers....

  9. Development of a Data Acquisition Software for the CULTASK Experiment

    Science.gov (United States)

    Lee, Soohyung

    2017-10-01

    Axion is a candidate of dark matter, and is a consequence of a solution to the strong CP problem. CULTASK (CAPP Ultra-Low Temperature Axion Search in Korea) is an axion search experiment which is being developed in Korea. As a part of the project, homegrown software, which governs the data acquisition and control systems, has been developed. The software governs the data acquisition as well as equipment control. In this proceeding, the development of the software is discussed.

  10. Automated support for experience-based software management

    Science.gov (United States)

    Valett, Jon D.

    1992-01-01

    To effectively manage a software development project, the software manager must have access to key information concerning a project's status. This information includes not only data relating to the project of interest, but also, the experience of past development efforts within the environment. This paper describes the concepts and functionality of a software management tool designed to provide this information. This tool, called the Software Management Environment (SME), enables the software manager to compare an ongoing development effort with previous efforts and with models of the 'typical' project within the environment, to predict future project status, to analyze a project's strengths and weaknesses, and to assess the project's quality. In order to provide these functions the tool utilizes a vast corporate memory that includes a data base of software metrics, a set of models and relationships that describe the software development environment, and a set of rules that capture other knowledge and experience of software managers within the environment. Integrating these major concepts into one software management tool, the SME is a model of the type of management tool needed for all software development organizations.

  11. Initial validation of ATLAS software on the ARM architecture

    Energy Technology Data Exchange (ETDEWEB)

    Kawamura, Gen; Quadt, Arnulf; Smith, Joshua Wyatt [II. Physikalisches Institut, Georg-August Universitaet Goettingen (Germany); Seuster, Rolf [TRIUMF (Canada); Stewart, Graeme [University of Glasgow (United Kingdom)

    2016-07-01

    In the early 2000's the introduction of the multi-core era of computing helped industry and experiments such as ATLAS realize even more computing power. This was necessary as the limits of what a single-core processor could do where quickly being reached. Our current model of computing is to increase the number of multi-core nodes in a server farm in order to handle the increased influx of data. As power costs and our need for more computing power increase, this model will eventually become non-realistic. Once again a paradigm shift has to take place. One such option is to look at alternative architectures for large scale server farms. ARM processors are such an example. Making up approximately 95 % of the smartphone and tablet market these processors are widely available, very power conservative and constantly becoming faster. The ATLAS software code base (Athena) is extremely complex comprising of more than 6.5 million lines of code. It has very recently been ported to the ARM 64-bit architecture. The process of our port as well as the first validation plots are presented and compared to the traditional x86 architecture.

  12. An Initial Quality Analysis of the Ohloh Software Evolution Data

    NARCIS (Netherlands)

    Bruntink, M.

    2014-01-01

    Large public data sets on software evolution promise great value to both researchers and practitioners, in particular for software (development) analytics. To realise this value, the data quality of such data sets needs to be studied and improved. Despite these data sets being of a secondary nature,

  13. Framework for Small-Scale Experiments in Software Engineering: Guidance and Control Software Project: Software Engineering Case Study

    Science.gov (United States)

    Hayhurst, Kelly J.

    1998-01-01

    Software is becoming increasingly significant in today's critical avionics systems. To achieve safe, reliable software, government regulatory agencies such as the Federal Aviation Administration (FAA) and the Department of Defense mandate the use of certain software development methods. However, little scientific evidence exists to show a correlation between software development methods and product quality. Given this lack of evidence, a series of experiments has been conducted to understand why and how software fails. The Guidance and Control Software (GCS) project is the latest in this series. The GCS project is a case study of the Requirements and Technical Concepts for Aviation RTCA/DO-178B guidelines, Software Considerations in Airborne Systems and Equipment Certification. All civil transport airframe and equipment vendors are expected to comply with these guidelines in building systems to be certified by the FAA for use in commercial aircraft. For the case study, two implementations of a guidance and control application were developed to comply with the DO-178B guidelines for Level A (critical) software. The development included the requirements, design, coding, verification, configuration management, and quality assurance processes. This paper discusses the details of the GCS project and presents the results of the case study.

  14. Software Reliability Analysis of NASA Space Flight Software: A Practical Experience.

    Science.gov (United States)

    Sukhwani, Harish; Alonso, Javier; Trivedi, Kishor S; Mcginnis, Issac

    2016-01-01

    In this paper, we present the software reliability analysis of the flight software of a recently launched space mission. For our analysis, we use the defect reports collected during the flight software development. We find that this software was developed in multiple releases, each release spanning across all software life-cycle phases. We also find that the software releases were developed and tested for four different hardware platforms, spanning from off-the-shelf or emulation hardware to actual flight hardware. For releases that exhibit reliability growth or decay, we fit Software Reliability Growth Models (SRGM); otherwise we fit a distribution function. We find that most releases exhibit reliability growth, with Log-Logistic (NHPP) and S-Shaped (NHPP) as the best-fit SRGMs. For the releases that experience reliability decay, we investigate the causes for the same. We find that such releases were the first software releases to be tested on a new hardware platform, and hence they encountered major hardware integration issues. Also such releases seem to have been developed under time pressure in order to start testing on the new hardware platform sooner. Such releases exhibit poor reliability growth, and hence exhibit high predicted failure rate. Other problems include hardware specification changes and delivery delays from vendors. Thus, our analysis provides critical insights and inputs to the management to improve the software development process. As NASA has moved towards a product line engineering for its flight software development, software for future space missions will be developed in a similar manner and hence the analysis results for this mission can be considered as a baseline for future flight software missions.

  15. Experiences with Software Quality Metrics in the EMI middleware

    Science.gov (United States)

    Alandes, M.; Kenny, E. M.; Meneses, D.; Pucciani, G.

    2012-12-01

    The EMI Quality Model has been created to define, and later review, the EMI (European Middleware Initiative) software product and process quality. A quality model is based on a set of software quality metrics and helps to set clear and measurable quality goals for software products and processes. The EMI Quality Model follows the ISO/IEC 9126 Software Engineering - Product Quality to identify a set of characteristics that need to be present in the EMI software. For each software characteristic, such as portability, maintainability, compliance, etc, a set of associated metrics and KPIs (Key Performance Indicators) are identified. This article presents how the EMI Quality Model and the EMI Metrics have been defined in the context of the software quality assurance activities carried out in EMI. It also describes the measurement plan and presents some of the metrics reports that have been produced for the EMI releases and updates. It also covers which tools and techniques can be used by any software project to extract “code metrics” on the status of the software products and “process metrics” related to the quality of the development and support process such as reaction time to critical bugs, requirements tracking and delays in product releases.

  16. Software for physics of tau lepton decay in LHC experiments

    CERN Document Server

    Przedzinski, Tomasz

    2010-01-01

    Software development in high energy physics experiments offers unique experience with rapidly changing environment and variety of different standards and frameworks that software must be adapted to. As such, regular methods of software development are hard to use as they do not take into account how greatly some of these changes influence the whole structure. The following thesis summarizes development of TAUOLA C++ Interface introducing tau decays to new event record standard. Documentation of the program is already published. That is why it is not recalled here again. We focus on the development cycle and methodology used in the project, starting from the definition of the expectations through planning and designing the abstract model and concluding with the implementation. In the last part of the paper we present installation of the software within different experiments surrounding Large Hadron Collider and the problems that emerged during this process.

  17. Initial conditions of radiative shock experiments

    Energy Technology Data Exchange (ETDEWEB)

    Kuranz, C. C.; Drake, R. P.; Krauland, C. M.; Marion, D. C.; Grosskopf, M. J.; Rutter, E.; Torralva, B.; Holloway, J. P. [Department of Atmospheric, Oceanic and Space Science, University of Michigan, Center for Radiative Shock Hydrodynamics, 2455 Hayward Dr., Ann Arbor, Michigan 48109 (United States); Bingham, D.; Goh, J. [Department of Statistics and Actuarial Science, Simon Fraser University, Burnaby, BC, Canada V5A 1S6 (Canada); Boehly, T. R.; Sorce, A. T. [Laboratory for Laser Energetics, University of Rochester, New York 14623 (United States)

    2013-05-15

    We performed experiments at the Omega Laser Facility to characterize the initial, laser-driven state of a radiative shock experiment. These experiments aimed to measure the shock breakout time from a thin, laser-irradiated Be disk. The data are then used to inform a range of valid model parameters, such as electron flux limiter and polytropic γ, used when simulating radiative shock experiments using radiation hydrodynamics codes. The characterization experiment and the radiative shock experiment use a laser irradiance of ∼7 × 10{sup 14} W cm{sup −2} to launch a shock in the Be disk. A velocity interferometer and a streaked optical pyrometer were used to infer the amount of time for the shock to move through the Be disk. The experimental results were compared with simulation results from the Hyades code, which can be used to model the initial conditions of a radiative shock system using the CRASH code.

  18. Experiences with Software Quality Metrics in the EMI Middleware

    CERN Multimedia

    CERN. Geneva

    2012-01-01

    The EMI Quality Model has been created to define, and later review, the EMI (European Middleware Initiative) software product and process quality. A quality model is based on a set of software quality metrics and helps to set clear and measurable quality goals for software products and processes. The EMI Quality Model follows the ISO/IEC 9126 Software Engineering – Product Quality to identify a set of characteristics that need to be present in the EMI software. For each software characteristic, such as portability, maintainability, compliance, etc, a set of associated metrics and KPIs (Key Performance Indicators) are identified. This article presents how the EMI Quality Model and the EMI Metrics have been defined in the context of the software quality assurance activities carried out in EMI. It also describes the measurement plan and presents some of the metrics reports that have been produced for the EMI releases and updates. It also covers which tools and techniques can be used by any software project t...

  19. Experiences with Software Quality Metrics in the EMI middlewate

    CERN Document Server

    Alandes, M; Meneses, D; Pucciani, G

    2012-01-01

    The EMI Quality Model has been created to define, and later review, the EMI (European Middleware Initiative) software product and process quality. A quality model is based on a set of software quality metrics and helps to set clear and measurable quality goals for software products and processes. The EMI Quality Model follows the ISO/IEC 9126 Software Engineering – Product Quality to identify a set of characteristics that need to be present in the EMI software. For each software characteristic, such as portability, maintainability, compliance, etc, a set of associated metrics and KPIs (Key Performance Indicators) are identified. This article presents how the EMI Quality Model and the EMI Metrics have been defined in the context of the software quality assurance activities carried out in EMI. It also describes the measurement plan and presents some of the metrics reports that have been produced for the EMI releases and updates. It also covers which tools and techniques can be used by any software project to ...

  20. Architectural design of experience based factory model for software ...

    African Journals Online (AJOL)

    A model which is based on experience factory approach has been proposed earlier, called. EBF-SD, to overcome the limitations of experience management in software development domain. An application prototype, which is then called SDeX, is developed based on the proposed model. The study on correlation analysis ...

  1. Software Cost and Schedule Estimating: A Process Improvement Initiative

    Science.gov (United States)

    1994-05-01

    their text on SADT’I" [ Marca 87], Marca and McGowan describe the different interfaces as "* Input: Things used and transformed. "* Control: Things that...Software Engineering Institute, Carnegie Mellon University, November 1991. [ Marca 87] Marca , D. A. and McGowan, C. L. Structured Analysis and Design

  2. Return to experience and initial wage level

    DEFF Research Database (Denmark)

    Sørensen, K.L.; Vejlin, R.

    2014-01-01

    This paper estimates the relationship between initial wage and return to experience. We use a Mincer-like wage model to non-parametrically estimate this relationship allowing for an unobservable individual permanent effect in wages and unobservable individual return to experience. The relationship...... between return to experience and unobservable individual ability is negative when conditioning on educational attainment, while the relationship between return to experience and educational attainment is positive. We link our findings to three main theories of wage growth, namely search, unobserved...

  3. Return to Experience and Initial Wage Level

    DEFF Research Database (Denmark)

    Sørensen, Kenneth Lykke; Vejlin, Rune Majlund

    This paper estimates the relationship between initial wage and return to experience. We use a Mincer-like wage model to nonparametrically estimate this relationship allowing for an unobservable individual permanent effect in wages and unobservable individual return to experience. The relationship...... between return to experience and unobservable individual ability is negative when conditioning on educational attainment while the relationship between return to experience and educational attainment is positive. We link our finding to two main theories of wage growth, namely search and human capital. We...

  4. Domain analysis for the reuse of software development experiences

    Science.gov (United States)

    Basili, V. R.; Briand, L. C.; Thomas, W. M.

    1994-01-01

    We need to be able to learn from past experiences so we can improve our software processes and products. The Experience Factory is an organizational structure designed to support and encourage the effective reuse of software experiences. This structure consists of two organizations which separates project development concerns from organizational concerns of experience packaging and learning. The experience factory provides the processes and support for analyzing, packaging, and improving the organization's stored experience. The project organization is structured to reuse this stored experience in its development efforts. However, a number of questions arise: What past experiences are relevant? Can they all be used (reused) on our current project? How do we take advantage of what has been learned in other parts of the organization? How do we take advantage of experience in the world-at-large? Can someone else's best practices be used in our organization with confidence? This paper describes approaches to help answer these questions. We propose both quantitative and qualitative approaches for effectively reusing software development experiences.

  5. Older people and smartwatches, initial experiences

    OpenAIRE

    Rosales Climent, Andrea; Fernández Ardèvol, Mireia; Comunello, Francesca; Mulargia, Simone; Ferran Ferrer, Núria

    2017-01-01

    While wearable technologies, such as smartwatches, are seen as an opportunity to solve some problems often related to older people (65+), e.g. emergencies, physical activity, or isolation, little is known about how older people would domesticate such new technologies. In this study we provided eleven older individuals with smartwatches and tracked their expectations and initial experiences using two interviews. According to our preliminary findings, previous experience with ICTs along with op...

  6. Muon Event Filter Software for the ATLAS Experiment at LHC

    CERN Document Server

    Biglietti, M; Assamagan, Ketevi A; Baines, J T M; Bee, C P; Bellomo, M; Bogaerts, J A C; Boisvert, V; Bosman, M; Caron, B; Casado, M P; Cataldi, G; Cavalli, D; Cervetto, M; Comune, G; Conde, P; Conde-Muíño, P; De Santo, A; De Seixas, J M; Di Mattia, A; Dos Anjos, A; Dosil, M; Díaz-Gómez, M; Ellis, Nick; Emeliyanov, D; Epp, B; Falciano, S; Farilla, A; George, S; Ghete, V M; González, S; Grothe, M; Kabana, S; Khomich, A; Kilvington, G; Konstantinidis, N P; Kootz, A; Lowe, A; Luminari, L; Maeno, T; Masik, J; Meessen, C; Mello, A G; Merino, G; Moore, R; Morettini, P; Negri, A; Nikitin, N V; Nisati, A; Padilla, C; Panikashvili, N; Parodi, F; Pinfold, J L; Pinto, P; Primavera, M; Pérez-Réale, V; Qian, Z; Resconi, S; Rosati, S; Santamarina-Rios, C; Scannicchio, D A; Schiavi, C; Segura, E; Sivoklokov, S Yu; Soluk, R A; Stefanidis, E; Sushkov, S; Sutton, M; Sánchez, C; Tapprogge, Stefan; Thomas, E; Touchard, F; Venda-Pinto, B; Ventura, A; Vercesi, V; Werner, P; Wheeler, S; Wickens, F J; Wiedenmann, W; Wielers, M; Zobernig, G; Computing In High Energy Physics

    2005-01-01

    At LHC the 40 MHz bunch crossing rate dictates a high selectivity of the ATLAS Trigger system, which has to keep the full physics potential of the experiment in spite of a limited storage capability. The level-1 trigger, implemented in a custom hardware, will reduce the initial rate to 75 kHz and is followed by the software based level-2 and Event Filter, usually referred as High Level Triggers (HLT), which further reduce the rate to about 100 Hz. In this paper an overview of the implementation of the offline muon recostruction algortihms MOORE (Muon Object Oriented REconstruction) and MuId (Muon Identification) as Event Filter in the ATLAS online framework is given. The MOORE algorithm performs the reconstruction inside the Muon Spectrometer providing a precise measurement of the muon track parameters outside the calorimeters; MuId combines the measurements of all ATLAS sub-detectors in order to identify muons and provides the best estimate of their momentum at the production vertex. In the HLT implementatio...

  7. Microscale Experiments in Chemistry: Initiatives in Implementation

    Indian Academy of Sciences (India)

    Home; Journals; Resonance – Journal of Science Education; Volume 6; Issue 11. Microscale Experiments in Chemistry: Initiatives in Implementation. Information and Announcements Volume 6 Issue 11 November 2001 pp 92-93. Fulltext. Click here to view fulltext PDF. Permanent link:

  8. TEACHING SOFTWARE FOR DESIGNING OF EXPERIMENTS (DOE IN WOODWORKING PROCESSES

    Directory of Open Access Journals (Sweden)

    Wilhelm LAURENZI

    2015-12-01

    Full Text Available This paper presents a teaching software that allows students and researchers to understand how passive and active experiments can be made, without making real experiments. The software generates experimental data for a wooden milling process based on an experimental design for two factors, y=f(x1, x2. The data pass through different modules which simulate a data acquisition system that convert the analog simulated data into digital data which are recorded into text files. The software has five modules: a process module, a current transformer module, a power transducer module, a data acquisition module and a file saving module. The interface of the software follows these modules and allows the user to set very easily the input and output values of every module. After simulation of all experiments and processing the recorded data, the experimental design can be completed with the measured values. With this information and with adequate software, a mathematical model of the process can be obtained very easily.

  9. Initial state radiation experiment at MAMI

    Directory of Open Access Journals (Sweden)

    Mihovilovič M.

    2014-05-01

    Full Text Available In an attempt to contribute further insight into the discrepancy between the Lamb shift and elastic scattering determinations of the proton charge radius, a new experiment at MAMI is underway, aimed at measuring proton form-factors at very low momentum transfers by using a new technique based on initial state radiation. This paper reports on the conclusions of the pilot measurement performed in 2010, whose main goal was to check the feasibility of the proposed experiment and to recognize and overcome any obstacles before running the full experiment. The modifications to the experimental apparatus are then explained which significantly improved the quality of data collected in the full scale experiment, which was successfully executed in August 2013. At the end first findings of the new experiment are discussed.

  10. Enhancing the Student Learning Experience in Software Engineering Project Courses

    Science.gov (United States)

    Marques, Maira; Ochoa, Sergio F.; Bastarrica, Maria Cecilia; Gutierrez, Francisco J.

    2018-01-01

    Carrying out real-world software projects in their academic studies helps students to understand what they will face in industry, and to experience first-hand the challenges involved when working collaboratively. Most of the instructional strategies used to help students take advantage of these activities focus on supporting agile programming,…

  11. Evaluating an Embedded Software Reference Architecture -- Industrial Experience Report

    NARCIS (Netherlands)

    Graaf, Bas; van Dijk, H.W.; van Deursen, Arie

    We discuss experiences gained during evaluation of the maintainability of a reference architecture in use at Oce, one of the worlds leading copier manufacturers. The evaluation is conducted using an approach based on SEIs Software Architecture Analysis Method (SAAM). The paper proposes a variant of

  12. An Initial Load-Based Green Software Defined Network

    Directory of Open Access Journals (Sweden)

    Ying Hu

    2017-05-01

    Full Text Available Software defined network (SDN is a new network architecture in which the control function is decoupled from the data forwarding plane, that is attracting wide attentions from both research and industry sectors. However, SDN still faces the energy waste problem as do traditional networks. At present, research on energy saving in SDN is mainly focused on the static optimization of the network with zero load when new traffic arrives, changing the transmission path of the uncompleted traffic which arrived before the optimization, possibly resulting in route oscillation and other deleterious effects. To avoid this, a dynamical energy saving optimization scheme in which the paths of the uncompleted flows will not be changed when new traffic arrives is designed. To find the optimal solution for energy saving, the problem is modeled as a mixed integer linear programming (MILP problem. As the high complexity of the problem prohibits the optimal solution, an improved heuristic routing algorithm called improved constant weight greedy algorithm (ICWGA is proposed to find a sub-optimal solution. Simulation results show that the energy saving capacity of ICWGA is close to that of the optimal solution, offering desirable improvement in the energy efficiency of the network.

  13. Software for the Integration of Multiomics Experiments in Bioconductor.

    Science.gov (United States)

    Ramos, Marcel; Schiffer, Lucas; Re, Angela; Azhar, Rimsha; Basunia, Azfar; Rodriguez, Carmen; Chan, Tiffany; Chapman, Phil; Davis, Sean R; Gomez-Cabrero, David; Culhane, Aedin C; Haibe-Kains, Benjamin; Hansen, Kasper D; Kodali, Hanish; Louis, Marie S; Mer, Arvind S; Riester, Markus; Morgan, Martin; Carey, Vince; Waldron, Levi

    2017-11-01

    Multiomics experiments are increasingly commonplace in biomedical research and add layers of complexity to experimental design, data integration, and analysis. R and Bioconductor provide a generic framework for statistical analysis and visualization, as well as specialized data classes for a variety of high-throughput data types, but methods are lacking for integrative analysis of multiomics experiments. The MultiAssayExperiment software package, implemented in R and leveraging Bioconductor software and design principles, provides for the coordinated representation of, storage of, and operation on multiple diverse genomics data. We provide the unrestricted multiple 'omics data for each cancer tissue in The Cancer Genome Atlas as ready-to-analyze MultiAssayExperiment objects and demonstrate in these and other datasets how the software simplifies data representation, statistical analysis, and visualization. The MultiAssayExperiment Bioconductor package reduces major obstacles to efficient, scalable, and reproducible statistical analysis of multiomics data and enhances data science applications of multiple omics datasets. Cancer Res; 77(21); e39-42. ©2017 AACR . ©2017 American Association for Cancer Research.

  14. C++ Software Quality in the ATLAS Experiment: Tools and Experience

    CERN Document Server

    Kluth, Stefan; The ATLAS collaboration; Obreshkov, Emil; Roe, Shaun; Seuster, Rolf; Snyder, Scott; Stewart, Graeme

    2016-01-01

    The ATLAS experiment at CERN uses about six million lines of code and currently has about 420 developers whose background is largely from physics. In this paper we explain how the C++ code quality is managed using a range of tools from compile-time through to run time testing and reflect on the great progress made in the last year largely through the use of static analysis tools such as Coverity®, an industry-standard tool which enables quality comparison with general open source C++ code. Other tools including cppcheck, Include-What-You-Use and run-time 'sanitizers' are also discussed.

  15. Online Monitoring software framework in the ATLAS experiment

    CERN Document Server

    Barczyk, M.; Caprini, M.; Da Silva Conceicao, J.; Dobson, M.; Flammer, J.; Jones, R.; Kazarov, A.; Kolos, S.; Liko, D.; Lucio, L.; Mapelli, L.; Soloviev, I.; Hart, R.; Amorim, A.; Klose, D.; Lima, J.; Pedro, L.; Wolters, H.; Badescu, E.; Alexandrov, I.; Kotov, V.; Mineev, M.; Ryabov, Yu.; CHEP 2003 Computing in High Energy Physics; Ryabov, Yu.

    2003-01-01

    A fast, efficient and comprehensive monitoring system is a vital part of any HEP experiment. This paper describes the software framework that will be used during ATLAS data taking to monitor the state of the data acquisition and the quality of physics data in the experiment. The framework has been implemented by the Online Software group of the ATLAS Trigger&Data Acquisition (TDAQ) project and has already been used for several years in the ATLAS test beams at CERN. The inter-process communication in the framework is implemented via CORBA, which provides portability between different operating systems and programming languages. This paper will describe the design and the most important aspects of the online monitoring framework implementation. It will also show some test results, which indicate the performance and scalability of the current implementation.

  16. Experiences on dynamic simulation software in chemical engineering education

    OpenAIRE

    Komulainen, Tiina M.; Enemark-Rasmussen, Rasmus; Sin, Gürkan; Fletcher, John P.; Cameron, David

    2012-01-01

    Commercial process simulators are increasing interest in the chemical engineer education. In this paper, the use of commercial dynamic simulation software, D-SPICE® and K-Spice®, for three different chemical engineering courses is described and discussed. The courses cover the following topics: basic chemical engineering, operability and safety analysis and process control. User experiences from both teachers and students are presented. The benefits of dynamic simulation as an additional teac...

  17. The Reconstruction Software for the Muon Ionization Cooling Experiment Trackers

    Science.gov (United States)

    Dobbs, A.; Long, K.; Santos, E.; Adey, D.; Hanlet, P.; Heidt, C.

    2014-06-01

    The international Muon Ionisation Cooling Experiment (MICE) is designed to demonstrate the principle of muon ionization cooling, for application to a future Neutrino Factory or Muon Collider. In order to measure the change in emittance, MICE is equipped with a pair of high precision scintillating fibre trackers. The trackers are required to measure a 10% change in emittance to 1% accuracy (giving an overall precision of 0.1%). This paper describes the tracker reconstruction software, as a part of the overall MICE software framework, MAUS. Channel clustering is described, proceeding to the formation of space-points, which are then associated with particle tracks using pattern recognition algorithms. Finally a full custom Kalman track fit is performed, to account for energy loss and multiple scattering. Exemplar results are shown for Monte Carlo data.

  18. The Reconstruction Software for the Muon Ionization Cooling Experiment Trackers

    Energy Technology Data Exchange (ETDEWEB)

    Dobbs, A. [Imperial Coll., London; Long, K. [Imperial Coll., London; Santos, E. [Imperial Coll., London; Adey, D. [Fermilab; Hanlet, P. [Fermilab; Heidt, C. [UC, Riverside

    2014-01-01

    The international Muon Ionisation Cooling Experiment (MICE) is designed to demonstrate the principle of muon ionization cooling, for application to a future Neutrino Factory or Muon Collider. In order to measure the change in emittance, MICE is equipped with a pair of high precision scintillating fibre trackers. The trackers are required to measure a 10% change in emittance to 1% accuracy (giving an overall precision of 0.1%). This paper describes the tracker reconstruction software, as a part of the overall MICE software framework, MAUS. Channel clustering is described, proceeding to the formation of space-points, which are then associated with particle tracks using pattern recognition algorithms. Finally a full custom Kalman track fit is performed, to account for energy loss and multiple scattering. Exemplar results are shown for Monte Carlo data.

  19. Barrier experiment: Shock initiation under complex loading

    Energy Technology Data Exchange (ETDEWEB)

    Menikoff, Ralph [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-01-12

    The barrier experiments are a variant of the gap test; a detonation wave in a donor HE impacts a barrier and drives a shock wave into an acceptor HE. The question we ask is: What is the trade-off between the barrier material and threshold barrier thickness to prevent the acceptor from detonating. This can be viewed from the perspective of shock initiation of the acceptor subject to a complex pressure drive condition. Here we consider key factors which affect whether or not the acceptor undergoes a shock-to-detonation transition. These include the following: shock impedance matches for the donor detonation wave into the barrier and then the barrier shock into the acceptor, the pressure gradient behind the donor detonation wave, and the curvature of detonation front in the donor. Numerical simulations are used to illustrate how these factors affect the reaction in the acceptor.

  20. Initial Cooling Experiments (ICE) at CERN

    CERN Document Server

    Krienen, F

    1980-01-01

    The Initial Cooling Experiment (ICE) has been a four-year study on the feasibility of high-energy proton-antiproton colliding beam experiments. It was realized that a cooling scheme aimed at increasing the phase-space density of the antiproton beam was essential for providing luminosities of the order of 10/sup 30/ cm/sup -2/ s/sup -1/ in the collider. Stochastic cooling of protons at about 2 GeV/c and electron cooling of protons at about 50 MeV kinetic energy were successfully tried in the ICE storage ring. During these tests it turned out that stochastic cooling alone would be sufficient to implement the 0.5 TeV c.m. collider of the CERN Super Proton Synchrotron (SPS). Besides physics at high energy, ICE opened up the road to antiproton physics at low (eventually very low) energies. This resulted in Project LEAR, now in the course of construction. It has been possible to cool, store, and stack antiprotons in ICE with a view to the determination of a lower limit on the antiproton lifetime. ICE has therefore ...

  1. Offline Software for the Mu2e Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Kutschke, Robert K. [Fermilab

    2012-01-01

    The Mu2e experiment at Fermilab is in the midst of its R&D and approval processes. To aid and inform this process, a small team has developed an end-to-end Geant4-based simulation package and has developed reconstruction code that is already at the stage of an advanced prototype. Having these tools available at an early stage allows design options and tradeoffs to be studied using high level physics quantities. A key to the success of this effort has been, as much as possible, to acquire software and customize it, rather than to build it in-house.

  2. Initial experience with lung transplantation in Estonia.

    Science.gov (United States)

    Laisaar, T; Savisaar, M; Parm, P; Sõrmus, A; Kuum, U; Ruusalepp, A; Jakobson, E; Küüsvek, A; Klepetko, W

    2013-04-01

    A lung transplant program in Estonia was initiated in cooperation with the Medical University of Vienna. The first lung transplantation for an Estonian patient was performed in Vienna on April 28, 2009. The waiting list in Estonia was opened on May 28, 2010; the first transplantation was performed on October 7, 2010. The aim of this study was to present our initial results. All lung transplantations performed in Estonia through the end of January 2012 included 2 female and 3 male patients of age from 52 to 64 years. Data regarding the donor, the transplant operation, postoperative period, and follow-up were extracted from case records. The cases included 1 bilateral lobar, 3 double, and 1 single lung transplantations. Two patients had chronic obstructive pulmonary disease, one alpha-1 trypsin deficiency, and two idiopathic pulmonary fibrosis. The operative duration varied from 172 to 337 minutes; the ischemia times for the first and second lung ranged from 191 to 351 and 303 to 455 minutes, respectively. Duration of postoperative mechanical ventilation ranged from 2 to 14 days (median 3) and the hospital stay from 28 to 72 days. The following complications were observed: prolonged air leak in 2 patients, one of whom required rethoracotomy; phrenic nerve palsy in 2, atrial fibrillation in 2, and mild renal failure in 1 subject. One patient needed readmission to the intensive care unit owing to acute respiratory failure; one, a tracheostomy for weaning from the ventilator, and one, noninvasive ventilation owing to hypercapnia. All patients remain well at 4-19 months after transplantation. No episodes of acute rejection or bronchiolitis obliterans have been diagnosed. The first 1.5-year experience with lung transplantation in Estonia has been satisfactory. Although there have been several complications, no posttransplant or waiting list mortality has occurred. Copyright © 2013 Elsevier Inc. All rights reserved.

  3. Subcutaneous implantable cardioverter-defibrillator: Initial experience.

    Science.gov (United States)

    Galvão, Pedro; Cavaco, Diogo; Adragão, Pedro; Costa, Francisco; Carmo, Pedro; Morgado, Francisco; Bernardo, Ricardo; Nunes, Manuela; Abecasis, Miguel; Neves, José; Mendes, Miguel

    2014-09-01

    Implantable cardioverter-defibrillators (ICDs) are important tools in the prevention of sudden death, but implantation requires transvenous access, which is associated with complications. Subcutaneous implantable cardioverter-defibrillators (S-ICDs) may prevent some of these complications. To evaluate the therapeutics and complications associated with S-ICD systems. S-ICD implantation was planned in 23 patients, for whom the indications were vascular access problems, increased risk of infection or young patients with long predicted follow-up. The population consisted of four patients with ischemic heart disease, three of them on hemodialysis (two with subclavian vein thrombosis), five with left ventricular noncompaction, four with Brugada syndrome, three with arrhythmogenic right ventricular cardiomyopathy, one with transposition of the great vessels, two with dilated cardiomyopathy and four with hypertrophic cardiomyopathy. S-ICDs were implanted in 21 patients, two having failed to fulfil the initial screening criteria. Mean implantation time was 77 minutes, with no complications. Defibrillation tests were performed, and in one patient the generator had to be repositioned to obtain an acceptable threshold. In a mean follow-up of 14 months, 10 patients had S-ICD shocks, which were appropriate in half of them; one developed infection, one needed early replacement due to loss of telemetry and one patient died of noncardiac cause. S-ICD implantation can be performed by cardiologists with a high success rate. Initial experience appears favorable, but further studies are needed with longer follow-up times to assess the safety and efficacy of this strategy compared to conventional devices. Copyright © 2013 Sociedade Portuguesa de Cardiologia. Published by Elsevier España. All rights reserved.

  4. Prostate brachytherapy in Ghana: our initial experience.

    Science.gov (United States)

    Mensah, James Edward; Yarney, Joel; Vanderpuye, Verna; Akpakli, Evans; Tagoe, Samuel; Sasu, Evans

    2016-10-01

    This study presents the experience of a brachytherapy team in Ghana with a focus on technology transfer and outcome. The team was initially proctored by experienced physicians from Europe and South Africa. A total of 90 consecutive patients underwent either brachytherapy alone or brachytherapy in combination with external beam radiotherapy for prostate carcinoma between July 2008 and February 2014 at Korle Bu Teaching Hospital, Accra, Ghana. Patients were classified as low-risk, intermediate, and high-risk according to the National Comprehensive Cancer Network (NCCN) criteria. All low-risk and some intermediate risk group patients were treated with seed implantation alone. Some intermediate and all high-risk group patients received brachytherapy combined with external beam radiotherapy. The median patient age was 64.0 years (range 46-78 years). The median follow-up was 58 months (range 18-74 months). Twelve patients experienced biochemical failure including one patient who had evidence of metastatic disease and died of prostate cancer. Freedom from biochemical failure rates for low, intermediate, and high-risk cases were 95.4%, 90.9%, and 70.8%, respectively. Clinical parameters predictive of biochemical outcome included: clinical stage, Gleason score, and risk group. Pre-treatment prostate specific antigen (PSA) was not a statistically significant predictor of biochemical failure. Sixty-nine patients (76.6%) experienced grade 1 urinary symptoms in the form of frequency, urgency, and poor stream. These symptoms were mostly self-limiting. Four patients needed catheterization for urinary retention (grade 2). One patient developed a recto urethral fistula (grade 3) following banding for hemorrhoids. Our results compare favorably with those reported by other institutions with more extensive experience. We believe therefore that, interstitial permanent brachytherapy can be safely and effectively performed in a resource challenged environment if adequate training

  5. Prostate brachytherapy in Ghana: our initial experience

    Directory of Open Access Journals (Sweden)

    James Edward Mensah

    2016-10-01

    Full Text Available Purpose: This study presents the experience of a brachytherapy team in Ghana with a focus on technology transfer and outcome. The team was initially proctored by experienced physicians from Europe and South Africa. Material and methods : A total of 90 consecutive patients underwent either brachytherapy alone or brachytherapy in combination with external beam radiotherapy for prostate carcinoma between July 2008 and February 2014 at Korle Bu Teaching Hospital, Accra, Ghana. Patients were classified as low-risk, intermediate, and high-risk according to the National Comprehensive Cancer Network (NCCN criteria. All low-risk and some intermediate risk group patients were treated with seed implantation alone. Some intermediate and all high-risk group patients received brachytherapy combined with external beam radiotherapy. Results: The median patient age was 64.0 years (range 46-78 years. The median follow-up was 58 months (range 18-74 months. Twelve patients experienced biochemical failure including one patient who had evidence of metastatic disease and died of prostate cancer. Freedom from biochemical failure rates for low, intermediate, and high-risk cases were 95.4%, 90.9%, and 70.8%, respectively. Clinical parameters predictive of biochemical outcome included: clinical stage, Gleason score, and risk group. Pre-treatment prostate specific antigen (PSA was not a statistically significant predictor of biochemical failure. Sixty-nine patients (76.6% experienced grade 1 urinary symptoms in the form of frequency, urgency, and poor stream. These symptoms were mostly self-limiting. Four patients needed catheterization for urinary retention (grade 2. One patient developed a recto urethral fistula (grade 3 following banding for hemorrhoids. Conclusions : Our results compare favorably with those reported by other institutions with more extensive experience. We believe therefore that, interstitial permanent brachytherapy can be safely and effectively

  6. 77 FR 1083 - Certain Portable Electronic Devices and Related Software; Determination Not To Review Initial...

    Science.gov (United States)

    2012-01-09

    ... COMMISSION Certain Portable Electronic Devices and Related Software; Determination Not To Review Initial... importation, and sale within the United States after importation of certain portable electronic devices and...'s electronic docket (EDIS) at http://edis.usitc.gov . Hearing-impaired persons are advised that...

  7. Laparoscopic herniorrhaphy: initial experience in 126 patients.

    Science.gov (United States)

    Darzi, A; Paraskeva, P A; Quereshi, A; Menzies-Gow, N; Guillou, P J; Monson, J R

    1994-06-01

    The initial experience in laparoscopic transabdominal preperitoneal mesh (TAPP) repairs is reviewed. In this study, consecutive TAPP repairs were performed in 126 patients. There were no intraoperative complications, and only 1 procedure had to be converted to open surgery. Forty-six patients had direct inguinal hernias, 56 had indirect inguinal hernias, and 24 had both, of which 21 were recurrent. Fifty-one hernias were right sided, 46 were left sided, and 29 were bilaterals. The male/female ratio was 116:10, and the mean age of the patients was 49.8 (range 17-76). Minor complications included parasthesia over the distribution of the lateral cutaneous nerve of the thigh in 2 patients, hydrocoeles in 2 patients, hematomata in 6 patients, and testicular pain in 4 patients, all of which resolved on conservative management. Incomplete bowel obstruction has been the only major postoperative complication to date, where an area of bowel herniated between two staples in the peritoneum. This was further complicated by an aspiration pneumonia and death of the patient. The mean hospital stay was 1.2 days (range 1-3), and the mean return to unrestricted activity was 8 days (range 3-12). There have been 2 true recurrences to date. One patient had a tender swelling after the repair, which was thought to be a recurrent strangulated hernia. On investigation, it was found to be a hematoma. The mean follow-up has been 7 months (range 1-18). Although early results of the TAPP repair are encouraging, we have had 1 significant complication that may have been avoided if an endoscopic extraperitoneal approach was employed.

  8. Object-oriented approach to software development for LHC experiments

    CERN Document Server

    O'Neale, S W; Dodgson, M; CERN. Geneva. Detector Research and Development Committee

    1994-01-01

    A proposal to study the viability of the Object Oriented (OO) approach for developing the code for LHC experiments. The authors will learn the key issues of this approach: OO analysis and design. Several methodologies will be studied to select the most appropiate for the High Energy Physics case. Some Computer Aided Software Engineering tools and implementation languages will be evaluated. These studies will be carried out with various well-defined prototypes, some of which have been defined in a preceding study and some of which will be defined in the course of this R&D project. It is also proposed to study how the OO approach enhances a different, and hopefully better, project management. Management tools will be tried and professional training will be organized.

  9. Object Oriented Approach to Software Development for LHC Experiments

    CERN Multimedia

    Tummers, B J; Day, C; Innocente, V; Mount, R; Visser, E; Burnett, T H; Balke, C

    2002-01-01

    % RD41 \\\\ \\\\ We propose to study the viability of the Object Oriented~(OO) approach for developing the code for LHC experiments. The authors of this proposal will learn the key issues of this approach:~~OO analysis and design. Several methodologies will be studied to select the most appropriate for the High Energy Physics case. Some Computer Aided Software Engineering tools and implementation languages will be evaluated. These studies will be carried out with various well-defined prototypes, some of which have been defined in a preceding study and some of which will be defined in the course of this R\\&D project. We propose to also study in this project how the OO approach enhances a different, and hopefully better, project management. Management tools will be tried and professional training will be organized.

  10. High energy physics experiment triggers and the trustworthiness of software

    Energy Technology Data Exchange (ETDEWEB)

    Nash, T.

    1991-10-01

    For all the time and frustration that high energy physicists expend interacting with computers, it is surprising that more attention is not paid to the critical role computers play in the science. With large, expensive colliding beam experiments now dependent on complex programs working at startup, questions of reliability -- the trustworthiness of software -- need to be addressed. This issue is most acute in triggers, used to select data to record -- and data to discard -- in the real time environment of an experiment. High level triggers are built on codes that now exceed 2 million source lines -- and for the first time experiments are truly dependent on them. This dependency will increase at the accelerators planned for the new millennium (SSC and LHC), where cost and other pressures will reduce tolerance for first run problems, and the high luminosities will make this on-line data selection essential. A sense of this incipient crisis motivated the unusual juxtaposition to topics in these lectures. 37 refs., 1 fig.

  11. Evaluating Open Source Software for Use in Library Initiatives: A Case Study Involving Electronic Publishing

    Science.gov (United States)

    Samuels, Ruth Gallegos; Griffy, Henry

    2012-01-01

    This article discusses best practices for evaluating open source software for use in library projects, based on the authors' experience evaluating electronic publishing solutions. First, it presents a brief review of the literature, emphasizing the need to evaluate open source solutions carefully in order to minimize Total Cost of Ownership. Next,…

  12. Software

    Energy Technology Data Exchange (ETDEWEB)

    Macedo, R.; Budd, G.; Ross, E.; Wells, P.

    2010-07-15

    The software section of this journal presented new software programs that have been developed to help in the exploration and development of hydrocarbon resources. Software provider IHS Inc. has made additions to its geological and engineering analysis software tool, IHS PETRA, a product used by geoscientists and engineers to visualize, analyze and manage well production, well log, drilling, reservoir, seismic and other related information. IHS PETRA also includes a directional well module and a decline curve analysis module to improve analysis capabilities in unconventional reservoirs. Petris Technology Inc. has developed a software to help manage the large volumes of data. PetrisWinds Enterprise (PWE) helps users find and manage wellbore data, including conventional wireline and MWD core data; analysis core photos and images; waveforms and NMR; and external files documentation. Ottawa-based Ambercore Software Inc. has been collaborating with Nexen on the Petroleum iQ software for steam assisted gravity drainage (SAGD) producers. Petroleum iQ integrates geology and geophysics data with engineering data in 3D and 4D. Calgary-based Envirosoft Corporation has developed a software that reduces the costly and time-consuming effort required to comply with Directive 39 of the Alberta Energy Resources Conservation Board. The product includes an emissions modelling software. Houston-based Seismic Micro-Technology (SMT) has developed the Kingdom software that features the latest in seismic interpretation. Holland-based Joa Oil and Gas and Calgary-based Computer Modelling Group have both supplied the petroleum industry with advanced reservoir simulation software that enables reservoir interpretation. The 2010 software survey included a guide to new software applications designed to facilitate petroleum exploration, drilling and production activities. Oil and gas producers can use the products for a range of functions, including reservoir characterization and accounting. In

  13. Experiment Software and Projects on the Web with VISPA

    Science.gov (United States)

    Erdmann, M.; Fischer, B.; Fischer, R.; Geiser, E.; Glaser, C.; Müller, G.; Rieger, M.; Urban, M.; von Cube, R. F.; Welling, C.

    2017-10-01

    The Visual Physics Analysis (VISPA) project defines a toolbox for accessing software via the web. It is based on latest web technologies and provides a powerful extension mechanism that enables to interface a wide range of applications. Beyond basic applications such as a code editor, a file browser, or a terminal, it meets the demands of sophisticated experiment-specific use cases that focus on physics data analyses and typically require a high degree of interactivity. As an example, we developed a data inspector that is capable of browsing interactively through event content of several data formats, e.g., MiniAOD which is utilized by the CMS collaboration. The VISPA extension mechanism can also be used to embed external web-based applications that benefit from dynamic allocation of user-defined computing resources via SSH. For example, by wrapping the JSROOT project, ROOT files located on any remote machine can be inspected directly through a VISPA server instance. We introduced domains that combine groups of users and role-based permissions. Thereby, tailored projects are enabled, e.g. for teaching where access to student’s homework is restricted to a team of tutors, or for experiment-specific data that may only be accessible for members of the collaboration. We present the extension mechanism including corresponding applications and give an outlook onto the new permission system.

  14. Experiences of engineering Grid-based medical software.

    Science.gov (United States)

    Estrella, F; Hauer, T; McClatchey, R; Odeh, M; Rogulin, D; Solomonides, T

    2007-08-01

    Grid-based technologies are emerging as potential solutions for managing and collaborating distributed resources in the biomedical domain. Few examples exist, however, of successful implementations of Grid-enabled medical systems and even fewer have been deployed for evaluation in practice. The objective of this paper is to evaluate the use in clinical practice of a Grid-based imaging prototype and to establish directions for engineering future medical Grid developments and their subsequent deployment. The MammoGrid project has deployed a prototype system for clinicians using the Grid as its information infrastructure. To assist in the specification of the system requirements (and for the first time in healthgrid applications), use-case modelling has been carried out in close collaboration with clinicians and radiologists who had no prior experience of this modelling technique. A critical qualitative and, where possible, quantitative analysis of the MammoGrid prototype is presented leading to a set of recommendations from the delivery of the first deployed Grid-based medical imaging application. We report critically on the application of software engineering techniques in the specification and implementation of the MammoGrid project and show that use-case modelling is a suitable vehicle for representing medical requirements and for communicating effectively with the clinical community. This paper also discusses the practical advantages and limitations of applying the Grid to real-life clinical applications and presents the consequent lessons learned. The work presented in this paper demonstrates that given suitable commitment from collaborating radiologists it is practical to deploy in practice medical imaging analysis applications using the Grid but that standardization in and stability of the Grid software is a necessary pre-requisite for successful healthgrids. The MammoGrid prototype has therefore paved the way for further advanced Grid-based deployments in the

  15. Robotic repair of vesicovaginal fistula - initial experience

    Directory of Open Access Journals (Sweden)

    Ankush Jairath

    2016-02-01

    Full Text Available ABSTRACT Objective The most common acquired fistula of the urinary tract is Vesicovaginal fistulae (VVF (1 posing social stigmata for the patient as well as a surgical challenge for the urologist. Here we present our initial experience with Robotic assisted laparoscopic repair of VVF, its safety and efficacy. Materials and Methods Seven out of eight fistulas were post hysterectomy; five had undergone abdominal while two had laparoscopic hysterectomy while one was due to prolonged labour. Two had associated ureteric injury. All underwent robotic assisted laparoscopic trans abdominal extravesical approach. Three 8 mm ports for robotic arms, one 12 mm port for camera and another 12 mm for assistant were used in a fan shaped manner. All had preoperative ureteric catheter placed. Bladder was closed in two layers and vagina in one layer. Omental flap placed in all cases except two where it was not possible. Drain and per urethral catheter placed in all cases. Double J stents were placed in two cases requiring ureteric implantation additionally. Results The mean age of presentation was 39.25 years (26-47 range with mean BMI being 26.25 kg/m2 (21-32 range. Mean duration between insult and repair was 9.37 months (3-24 months. Only in single case there was history of previous repair attempt. On cystoscopy four had supratrigonal VVF and four were trigonal with mean size of 13.37 mm (7-20 mm. Mean operative time was 117.5 minutes (90-150. There were no intraoperative/postoperative complications or need for open conversion. Mean haemoglobin drop was 1.4 gm/dL (0.3-2 gm. Drain was removed once 24-48 hours output is negligible. One patient had post-operative urinary leak at 2 weeks which ceased with continuation of catheterisation for another 2 weeks. Catheter was removed after voiding cystourethrogram showed no leak at 2-3 weeks postoperatively. Mean duration of drain was 3.75 days (3-5 and per urethral catheterisation (which was removed after voiding

  16. Closing the loop on improvement: Packaging experience in the Software Engineering Laboratory

    Science.gov (United States)

    Waligora, Sharon R.; Landis, Linda C.; Doland, Jerry T.

    1994-01-01

    As part of its award-winning software process improvement program, the Software Engineering Laboratory (SEL) has developed an effective method for packaging organizational best practices based on real project experience into useful handbooks and training courses. This paper shares the SEL's experience over the past 12 years creating and updating software process handbooks and training courses. It provides cost models and guidelines for successful experience packaging derived from SEL experience.

  17. Initial experiments with Multiple Musical Gestures

    DEFF Research Database (Denmark)

    Jensen, Kristoffer; Graugaard, Lars

    2005-01-01

    other manipulation gestures. The initial position controls which parameter is being affected, the notes intensity is controlled by the downward gesture speed, and a sequence is finalized instantly with one upward gesture. The synthesis employs a novel interface structure, the multiple musical gesture...

  18. Initial Encounters : The Lived Experiences of Buyers

    NARCIS (Netherlands)

    G. Wright; J.J. Dekker

    2012-01-01

    The initial encounter between a buyer and a seller has received much attention among practitioners. The first time a buyer interacts with a seller is thought to be highly influential. The premise is that buyers form an opinion during this first encounter, or even the first minutes of this encounter.

  19. Continuous Software Quality analysis for the ATLAS experiment

    CERN Document Server

    Washbrook, Andrew; The ATLAS collaboration

    2017-01-01

    The regular application of software quality tools in large collaborative projects is required to reduce code defects to an acceptable level. If left unchecked the accumulation of defects invariably results in performance degradation at scale and problems with the long-term maintainability of the code. Although software quality tools are effective for identification there remains a non-trivial sociological challenge to resolve defects in a timely manner. This is a ongoing concern for the ATLAS software which has evolved over many years to meet the demands of Monte Carlo simulation, detector reconstruction and data analysis. At present over 3.8 million lines of C++ code (and close to 6 million total lines of code) are maintained by a community of hundreds of developers worldwide. It is therefore preferable to address code defects before they are introduced into a widely used software release. Recent wholesale changes to the ATLAS software infrastructure have provided an ideal opportunity to apply software quali...

  20. Experience with case tools in the design of process-oriented software

    CERN Document Server

    Novakov, O

    1993-01-01

    In Accelerator systems such as the CERN PS complex, process equipment has a life time which may exceed the typical life cycle of its related software. Taking in account the variety of such equipment, it is important to keep the analysis and design of the software in a system- independent form. This paper discusses the experience gathered in using commercial CASE tools for analysis, design and reverse engineering of different process- oriented software modules, with a principal emphasis on maintaining the initial analysis in a standardized form. Such tools are in existence for several years, but this paper shows that they are not entirely adapted to our needs.In particular, the paper stresses the problems of integrating such a tool in an existing data-base-dependent development chain, the lack of real-time simulation tools and of object-oriented concepts in existing commercial packages. Finally, the paper attempts to show a broader view of software engineering needs in our particular context.

  1. Systems and software variability management concepts, tools and experiences

    CERN Document Server

    Capilla, Rafael; Kang, Kyo-Chul

    2013-01-01

    The success of product line engineering techniques in the last 15 years has popularized the use of software variability as a key modeling approach for describing the commonality and variability of systems at all stages of the software lifecycle. Software product lines enable a family of products to share a common core platform, while allowing for product specific functionality being built on top of the platform. Many companies have exploited the concept of software product lines to increase the resources that focus on highly differentiating functionality and thus improve their competitiveness

  2. Experience Supporting the Integration of LHC Experiments Software Framework with the LCG Middleware

    CERN Document Server

    Santinelli, Roberto

    2006-01-01

    The LHC experiments are currently preparing for data acquisition in 2007 and because of the large amount of required computing and storage resources, they decided to embrace the grid paradigm. The LHC Computing Project (LCG) provides and operates a computing infrastructure suitable for data handling, Monte Carlo production and analysis. While LCG offers a set of high level services, intended to be generic enough to accommodate the needs of different Virtual Organizations, the LHC experiments software framework and applications are very specific and focused on the computing and data models. The LCG Experiment Integration Support team works in close contact with the experiments, the middleware developers and the LCG certification and operations teams to integrate the underlying grid middleware with the experiment specific components. The strategical position between the experiments and the middleware suppliers allows EIS team to play a key role at communications level between the customers and the service provi...

  3. Multi-threaded software framework development for the ATLAS experiment

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00226135; Baines, John; Bold, Tomasz; Calafiura, Paolo; Dotti, Andrea; Farrell, Steven; Leggett, Charles; Malon, David; Ritsch, Elmar; Snyder, Scott; Tsulaia, Vakhtang; van Gemmeren, Peter; Wynne, Benjamin

    2016-01-01

    ATLAS's current software framework, Gaudi/Athena, has been very successful for the experiment in LHC Runs 1 and 2. However, its single threaded design has been recognised for some time to be increasingly problematic as CPUs have increased core counts and decreased available memory per core. Even the multi-process version of Athena, AthenaMP, will not scale to the range of architectures we expect to use beyond Run2. ATLAS examined the requirements on an updated multi-threaded framework and laid out plans for a new framework, including better support for high level trigger (HLT) use cases, in 2014. In this paper we report on our progress in developing the new multi-threaded task parallel extension of Athena, AthenaMT. Implementing AthenaMT has required many significant code changes. Progress has been made in updating key concepts of the framework, to allow the incorporation of different levels of thread safety in algorithmic code (from un-migrated thread-unsafe code, to thread safe copyable code to reentrant co...

  4. Multi-threaded Software Framework Development for the ATLAS Experiment

    CERN Document Server

    Stewart, Graeme; The ATLAS collaboration; Baines, John; Calafiura, Paolo; Dotti, Andrea; Farrell, Steven; Leggett, Charles; Malon, David; Ritsch, Elmar; Snyder, Scott; Tsulaia, Vakhtang; van Gemmeren, Peter; Wynne, Benjamin

    2016-01-01

    ATLAS's current software framework, Gaudi/Athena, has been very successful for the experiment in LHC Runs 1 and 2. However, its single threaded design has been recognised for some time to be increasingly problematic as CPUs have increased core counts and decreased available memory per core. Even the multi-process version of Athena, AthenaMP, will not scale to the range of architectures we expect to use beyond Run2. ATLAS examined the requirements on an updated multi-threaded framework and layed out plans for a new framework, including better support for high level trigger (HLT) use cases, in 2014. In this paper we report on our progress in developing the new multi-threaded task parallel extension of Athena, AthenaMT. Implementing AthenaMT has required many significant code changes. Progress has been made in updating key concepts of the framework, to allow the incorporation of different levels of thread safety in algorithmic code (from un-migrated thread-unsafe code, to thread safe copyable code to reentrant c...

  5. Enabling software defined networking experiments in networked critical infrastructures

    Directory of Open Access Journals (Sweden)

    Béla Genge

    2014-05-01

    Full Text Available Nowadays, the fact that Networked Critical Infrastructures (NCI, e.g., power plants, water plants, oil and gas distribution infrastructures, and electricity grids, are targeted by significant cyber threats is well known. Nevertheless, recent research has shown that specific characteristics of NCI can be exploited in the enabling of more efficient mitigation techniques, while novel techniques from the field of IP networks can bring significant advantages. In this paper we explore the interconnection of NCI communication infrastructures with Software Defined Networking (SDN-enabled network topologies. SDN provides the means to create virtual networking services and to implement global networking decisions. It relies on OpenFlow to enable communication with remote devices and has been recently categorized as the “Next Big Technology”, which will revolutionize the way decisions are implemented in switches and routers. Therefore, the paper documents the first steps towards enabling an SDN-NCI and presents the impact of a Denial of Service experiment over traffic resulting from an XBee sensor network which is routed across an emulated SDN network.

  6. Initial experience with laparoscopic splenectomy for immune ...

    African Journals Online (AJOL)

    since become the preferred method of splenectomy for refractory. ITP.[3] Laparoscopic splenectomy compares favourably with open splenectomy with regard to postoperative pain, length of hospital stay and return to normal daily activity.[4-6]. We present our experience with the introduction of laparoscopic splenectomy at a ...

  7. Experiences with Integrating Simulation into a Software Engineering Curriculum

    Science.gov (United States)

    Bollin, Andreas; Hochmuller, Elke; Mittermeir, Roland; Samuelis, Ladislav

    2012-01-01

    Software Engineering education must account for a broad spectrum of knowledge and skills software engineers will be required to apply throughout their professional life. Covering all the topics in depth within a university setting is infeasible due to curricular constraints as well as due to the inherent differences between educational…

  8. Understanding software developers’ awareness and knowledge about user experience and usability

    Directory of Open Access Journals (Sweden)

    Yavuz İnal

    2016-10-01

    Full Text Available This study aimed to understand software developers’ awareness and level of knowledge about user experience and usability. The study also examined software developers’ opinions regarding integrating usability activities into software development processes. Fifty-nine software developers participated to the study. In the first part of the study, data were collected through questionnaire. In the second part of the study, in-depth interviews were conducted with a group of volunteer participants and detailed information was obtained about the topic. Results of the study revealed that majority of the software developers did not have any training related to user experience, usability or human-computer interaction. The majority of the participants consider themselves as the least experienced and uninformed members of a software development project about user experience and usability. The results also revealed that software developers in the study have incomplete and misinformation about user experience and usability.

  9. An experience of qualified preventive screening: shiraz smart screening software.

    Science.gov (United States)

    Islami Parkoohi, Parisa; Zare, Hashem; Abdollahifard, Gholamreza

    2015-01-01

    Computerized preventive screening software is a cost effective intervention tool to address non-communicable chronic diseases. Shiraz Smart Screening Software (SSSS) was developed as an innovative tool for qualified screening. It allows simultaneous smart screening of several high-burden chronic diseases and supports reminder notification functionality. The extent in which SSSS affects screening quality is also described. Following software development, preventive screening and annual health examinations of 261 school staff (Medical School of Shiraz, Iran) was carried out in a software-assisted manner. To evaluate the quality of the software-assisted screening, we used quasi-experimental study design and determined coverage, irregular attendance and inappropriateness proportions in relation with the manual and software-assisted screening as well as the corresponding number of requested tests. In manual screening method, 27% of employees were covered (with 94% irregular attendance) while by software-assisted screening, the coverage proportion was 79% (attendance status will clear after the specified time). The frequency of inappropriate screening test requests, before the software implementation, was 41.37% for fasting plasma glucose, 41.37% for lipid profile, 0.84% for occult blood, 0.19% for flexible sigmoidoscopy/colonoscopy, 35.29% for Pap smear, 19.20% for mammography and 11.2% for prostate specific antigen. All of the above were corrected by the software application. In total, 366 manual screening and 334 software-assisted screening tests were requested. SSSS is an innovative tool to improve the quality of preventive screening plans in terms of increased screening coverage, reduction in inappropriateness and the total number of requested tests.

  10. An Experience of Qualified Preventive Screening: Shiraz Smart Screening Software

    Directory of Open Access Journals (Sweden)

    Parisa Islami Parkoohi

    2015-01-01

    Full Text Available Background: Computerized preventive screening software is a cost effective intervention tool to address non-communicable chronic diseases. Shiraz Smart Screening Software (SSSS was developed as an innovative tool for qualified screening. It allows simultaneous smart screening of several high-burden chronic diseases and supports reminder notification functionality. The extent in which SSSS affects screening quality is also described. Methods: Following software development, preventive screening and annual health examinations of 261 school staff (Medical School of Shiraz, Iran was carried out in a software-assisted manner. To evaluate the quality of the software-assisted screening, we used quasi-experimental study design and determined coverage, irregular attendance and inappropriateness proportions in relation with the manual and software-assisted screening as well as the corresponding number of requested tests. Results: In manual screening method, 27% of employees were covered (with 94% irregular attendance while by software-assisted screening, the coverage proportion was 79% (attendance status will clear after the specified time. The frequency of inappropriate screening test requests, before the software implementation, was 41.37% for fasting plasma glucose, 41.37% for lipid profile, 0.84% for occult blood, 0.19% for flexible sigmoidoscopy/colonoscopy, 35.29% for Pap smear, 19.20% for mammography and 11.2% for prostate specific antigen. All of the above were corrected by the software application. In total, 366 manual screening and 334 software-assisted screening tests were requested. Conclusion: SSSS is an innovative tool to improve the quality of preventive screening plans in terms of increased screening coverage, reduction in inappropriateness and the total number of requested tests.

  11. Experience with a new approach for instrument software at Gemini

    Science.gov (United States)

    Núñez, Arturo; Walker, Shane; Goodsell, Stephen; Dunn, Jennifer; Gillies, Kim

    2010-07-01

    Gemini Observatory is using a new approach with instrument software that takes advantage of the strengths of our instrument builders and at the same time better supports our own operational needs. A lightweight software library in conjunction with modern agile software development methodologies is being used to ameliorate the problems encountered with the development of the first and second-generation Gemini instruments. Over the last two years, Gemini and the team constructing the software for the Gemini Planet Imager (GPI) have been using an agile development process to implement the Gemini Instrument Application Interface (GIAPI) and the highlevel control software for the GPI instrument. The GPI is being tested and exercised with the GIAPI, and this has allowed us to perform early end-to-end testing of the instrument software. Early in 2009 for the first time in our development history, we were able to move instrument mechanisms with Gemini software during early instrument construction. As a result of this approach, we discovered and fixed software interface issues between Gemini and GPI. Resolving these problems at this stage is simpler and less expensive than when the full instrument is completed. GPI is currently approaching its integration and testing phase, which will occur in 2010. We expect that utilizing this new approach will yield a more robust software implementation resulting in smoother instrument integration, testing, and commissioning phases. In this paper we describe the key points of our approach and results of applying the new instrument API approach together with agile development methodologies. The paper concludes with lessons learned and suggestions for adapting agile approaches in other astronomy development projects.

  12. Initial results from the PIENU experiment

    Science.gov (United States)

    Sullivan, T.; Aguilar-Arevalo, A.; Aoki, M.; Blecher, M.; Britton, D. I.; Bryman, D. A.; Bruch, D. vom; Chen, S.; Comfort, J.; Cuen-Rochin, S.; Doria, L.; Gumplinger, P.; Hussein, A.; Igarashi, Y.; Ito, S.; Kettell, S. H.; Kurchaninov, L.; Littenberg, L. S.; Malbrunot, C.; Mischke, R. E.; Numao, T.; Protopopescu, D.; Sher, A.; Vavilov, D.

    2017-11-01

    The pion branching ratio, R_{π } = { {Γ }(π + → e+ ν e + π +→ e+ ν e γ )}/{Γ (π + → μ + ν _{μ } + π + → μ + ν _{μ } γ )}, provides a sensitive test of lepton universality and constraints on many new physics scenarios. The theoretical uncertainty on the Standard Model prediction of R π is 0.02 %, a factor of twenty smaller than the experimental uncertainty. The analysis of a subset of data taken by the PIENU experiment will be presented. The result, R π = (1.2344 ± 0.0023( s t a t) ± 0.0019( s y s t)) ṡ 10-4 [1], is consistent with the Standard Model prediction and represents a 0.1 % constraint on lepton non-universality.

  13. Laparoscopic nephrectomy: initial experience with 120 cases.

    LENUS (Irish Health Repository)

    Cheema, I A

    2012-02-01

    Laparoscopic nephrectomy for both benign and malignant diseases of kidney is increasingly being performed. We report our experience with the first 120 consecutive laparoscopic nephrectomy performed in our hospital. It is the retrospective analysis of a prospectively maintained database of 4 years period. The parameters examined included age, gender, indications, operative time, blood loss, intraoperative and post operative complications. Mean age of surgery was 59 years (rang 19-84years). The indications for surgery included solid renal masses (71 patients), non-functioning kidneys (43), and collecting system tumours (6). The mean operating time was 132 minutes (range 75-270), average blood loss was 209 ml (range 0-1090) and average hospital stay was 4.7days (range 2-20). Bleeding, bowel injury and poor progression of laparoscopic procedure were the reasons in 7 (5.8%) cases converted to open surgery. There was 1 (0.8%) perioperative mortality. Eight (6.6%) patients developed post operative complications. Laparoscopic nephrectomy has inherent benefits and may be considered an alternate therapeutic option for kidney diseases with acceptable morbidity

  14. Laparoscopic nephrectomy: initial experience with 120 cases.

    LENUS (Irish Health Repository)

    Cheema, I A

    2010-02-01

    Laparoscopic nephrectomy for both benign and malignant diseases of kidney is increasingly being performed. We report our experience with the first 120 consecutive laparoscopic nephrectomy performed in our hospital. It is the retrospective analysis of a prospectively maintained database of 4 years period. The parameters examined included age, gender, indications, operative time, blood loss, intraoperative and post operative complications. Mean age of surgery was 59 years (rang 19-84years). The indications for surgery included solid renal masses (71 patients), non-functioning kidneys (43), and collecting system tumours (6). The mean operating time was 132 minutes (range 75-270), average blood loss was 209 ml (range 0-1090) and average hospital stay was 4.7days (range 2-20). Bleeding, bowel injury and poor progression of laparoscopic procedure were the reasons in 7 (5.8%) cases converted to open surgery. There was 1 (0.8%) perioperative mortality. Eight (6.6%) patients developed post operative complications. Laparoscopic nephrectomy has inherent benefits and may be considered an alternate therapeutic option for kidney diseases with acceptable morbidity

  15. Our Initial Experiences with Laparoscopic Urologic Surgery

    Directory of Open Access Journals (Sweden)

    Selçuk Altın

    2016-03-01

    Full Text Available Objective: Retrospectively, to evaluate outcomes and complications of urological laparoscopic surgery cases performed in our clinic. Methods: A total of 115 patients who received laparo­scopic surgery between January 2012 and January 2015 were retrospectively evaluated. Included patients were assessed in terms of demographic characteristics, pre­operative diagnosis, type of laparoscopic approach, dura­tion of surgery and hospitalization, complications before and after surgery, and postoperative requirement for open surgery. Results: 61 of included patients were women, 54 were male, and the mean age was 52.4±11.7 years. Sixty-eight patients underwent transperitoneal and 47 patients re­ceived retroperitoneal procedures. While 29 patients re­ceived renal cyst excision, 25 had simple nephrectomy, 22 had ureterolithotomy, 19 had radical nephrectomy, 15 had pyelolithotomy and 5 had pyeloplasty. Four (3,4% of the 115 patients required converting to open surgery. Except these patients, no major complication or mortal­ity was encountered. The mean duration of surgery for the most commonly applied procedures were as follows: renal cyst excision 62 (50-110 min, simple nephrectomy 125 (95-140 min, ureterolithotomy 108 (90-130 min, rad­ical nephrectomy 141 (105-175 min, pyelolithotomy 116 (95-140 min, and pyeloplasty 166 (150-190 min. The mean hospital stay was 3.7±2.8 (2-11 days. Conclusion: The success and complication rates of the laparoscopic surgeries performed in our clinic were con­sistent with those reported in the literature. In the light of technological advances and increasing experience, as well as based on the higher tolerance exhibited by pa­tients, we believe that laparoscopic surgery is a minimally invasive method that is a safe alternative to open surgery.

  16. Open Source Software Development with Your Mother Language : Intercultural Collaboration Experiment 2002

    DEFF Research Database (Denmark)

    Nomura, Saeko; Ishida, Saeko; Jensen, Mika Yasuoka

    2002-01-01

    ”Open Source Software Development with Your Mother Language: Intercultural Collaboration Experiment 2002,” 10th International Conference on Human – Computer Interaction (HCII2003), June 2003, Crete, Greece.......”Open Source Software Development with Your Mother Language: Intercultural Collaboration Experiment 2002,” 10th International Conference on Human – Computer Interaction (HCII2003), June 2003, Crete, Greece....

  17. The Qualification Experiences for Safety-critical Software of POSAFE-Q

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Jang Yeol; Son, Kwang Seop; Cheon, Se Woo; Lee, Jang Soo; Kwon, Kee Choon [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2009-05-15

    Programmable Logic Controllers (PLC) have been applied to the Reactor Protection System (RPS) and the Engineered Safety Feature (ESF)-Component Control System (CCS) as the major safety system components of nuclear power plants. This paper describes experiences on the qualification of the safety-critical software including the pCOS kernel and system tasks related to a safety-grade PLC, i.e. the works done for the Software Verification and Validation, Software Safety Analysis, Software Quality Assurance, and Software Configuration Management etc.

  18. Experiences from Designing and Validating a Software Modernization Transformation

    DEFF Research Database (Denmark)

    Iosif-Lazăr, Alexandru Florin; Al-Sibahi, Ahmad Salim; Dimovski, Aleksandar

    2015-01-01

    Software modernization often involves complex code transformations that convert legacy code to new architectures or platforms, while preserving the semantics of the original programs. We present the lessons learnt from an industrial software modernization project of considerable size. This includes...... collecting requirements for a code-to-model transformation, designing and implementing the transformation algorithm, and then validating correctness of this transformation for the code-base at hand. Our transformation is implemented in the TXL rewriting language and assumes specifically structured C++ code...... as input, which it translates to a declarative configuration model. The correctness criterion for the transformation is that the produced model admits the same configurations as the input code. The transformation converts C++ functions specifying around a thousand configuration parameters. We verify...

  19. A REVIEW OF SOFTWARE-INDUCED FAILURE EXPERIENCE.

    Energy Technology Data Exchange (ETDEWEB)

    CHU, T.L.; MARTINEZ-GURIDI, G.; YUE, M.; LEHNER, J.

    2006-09-01

    We present a review of software-induced failures in commercial nuclear power plants (NPPs) and in several non-nuclear industries. We discuss the approach used for connecting operational events related to these failures and the insights gained from this review. In particular, we elaborate on insights that can be used to model this kind of failure in a probabilistic risk assessment (PRA) model. We present the conclusions reached in these areas.

  20. Experience Report: Introducing Kanban Into Automotive Software Project

    Directory of Open Access Journals (Sweden)

    Marek Majchrzak

    2017-03-01

    Full Text Available The boundaries between traditional and agile approach methods are disappearing. A significant number of software projects require a continuous implementation of tasks without dividing them into sprints or strict project phases. Customers expect more flexibility and responsiveness from software vendors in response to the ever-changing business environment. To achieve better results in this field, Capgemini has begun using the Lean philosophy and Kanban techniques. \\\\The following article illustrates examples of different uses of Kanban and the main stakeholder of the process. The article presents the main advantages of transparency and ways to improve the customer co-operation as well as stakeholder relationships. The Authors try to visualise all of the elements in the context of the project. \\\\There is also a discussion of different approaches in two software projects. The article fokuses on the main challenges and the evolutionary approach used. An attempt is made to answer the question how to convince both the team as well as the customer, and how to optimise ways to achieve great results.

  1. Experiences on dynamic simulation software in chemical engineering education

    DEFF Research Database (Denmark)

    Komulainen, Tiina M.; Enemark-rasmussen, Rasmus; Sin, Gürkan

    2012-01-01

    : basic chemical engineering, operability and safety analysis and process control. User experiences from both teachers and students are presented. The benefits of dynamic simulation as an additional teaching tool are discussed and summarized. The experiences confirm that commercial dynamic simulators...... provide realistic training and can be successfully integrated into undergraduate and graduate teaching, laboratory courses and research....

  2. Report on the Second Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE2

    Directory of Open Access Journals (Sweden)

    Daniel S. Katz

    2016-02-01

    Full Text Available This technical report records and discusses the Second Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE2. The report includes a description of the alternative, experimental submission and review process, two workshop keynote presentations, a series of lightning talks, a discussion on sustainability, and five discussions from the topic areas of exploring sustainability; software development experiences; credit & incentives; reproducibility & reuse & sharing; and code testing & code review. For each topic, the report includes a list of tangible actions that were proposed and that would lead to potential change. The workshop recognized that reliance on scientific software is pervasive in all areas of world-leading research today. The workshop participants then proceeded to explore different perspectives on the concept of sustainability. Key enablers and barriers of sustainable scientific software were identified from their experiences. In addition, recommendations with new requirements such as software credit files and software prize frameworks were outlined for improving practices in sustainable software engineering. There was also broad consensus that formal training in software development or engineering was rare among the practitioners. Significant strides need to be made in building a sense of community via training in software and technical practices, on increasing their size and scope, and on better integrating them directly into graduate education programs. Finally, journals can define and publish policies to improve reproducibility, whereas reviewers can insist that authors provide sufficient information and access to data and software to allow them reproduce the results in the paper. Hence a list of criteria is compiled for journals to provide to reviewers so as to make it easier to review software submitted for publication as a “Software Paper.” 

  3. Teaching First Degree Functions - Experiment, Free Software and Media

    Science.gov (United States)

    Camargo, Denilso; Rocha, Josy

    2011-07-01

    This work provides students the opportunity to develop the ability to establish relationships between different fields of knowledge through activities involving mathematics and physics. We engage students in a series of activities that lead them to understand the concept of function, particularly the first-degree function and its applications. We begin the study of the functions with an experimental approach that links the study of uniform motion in physics to the study of the first degree function in the mathematics. Winplot software is subsequently used to consolidate the concept of the function, as well as analyse the effect on the graph of varying the parameters in the equation that describes it. Finally, students are invited to select and analyse graphs from published sources (e.g. newspapers and magazines) applying the skills developed.

  4. [Establishment and evaluation of a computer-based software system for detection of initial approximal caries].

    Science.gov (United States)

    Li, Yun; Ye, Wei-ping; Li, Yu-jing; Yu, Yang

    2006-03-01

    To establish and evaluate a computer-based software system (caries diagnosing system, CDS): CDS for better detection of initial approximal caries based on the performance of radiography. A total of 190 approximal surfaces from 95 extracted posterior teeth were examined by bite-wing radiography. After analysing and extracting the approximal lesion's characteristics of X-ray performance, using Matlab and VC language, the CDS was established. Then the proximal surfaces of these teeth were detected automatically by CDS, and scored by naked eyes of 8 experienced dentists for the extent of lesions. The histological appearance of sectioned teeth was used as the gold standard to assess sensitivity, specificity, accuracy, and reproducibility. The sensitivity of CDS was 0.728, Pearson's correlation was 0.722, better than that of optic estimation. The reproducibility of CDS was good too. The CDS can report the lesion site and extension, its diagnostic level is better than that of optic estimation, it is an reasonably sensitive and accurate method for the detection of initial approximal caries in present clinic practice, and a tool of providing objective data.

  5. Front-End-Electronics Communication software for multiple detectors in the ALICE experiment

    CERN Document Server

    Bablok, Sebastian; Hartung, G; Keidel, R; Kofler, C; Krawutschke, T; Lindenstruth, V; Röhrich, D

    2006-01-01

    In the ALICE experiment at CERN, the Detector Control System (DCS) employs several interacting software components to accomplish its task of ensuring the correct operation and monitoring of the experiment. This paper describes the Front-End-Electronics Communication (FeeCommunication) software and its role within the DCS. The FeeCommunication software's central task is passing configuration and monitoring data between the top level DCS process control and the field devices of several detectors within ALICE. The lowest level of the FeeCommunication software runs on the DCS boards, specialized embedded systems which are in direct contact with the field devices and are physically located within the detector. The middle and upper layers run on standard PC hardware located in the counting room or other external locations. This paper focuses on the design and implementation of the FeeCommunication software and the steps that were taken to fulfill the imposed reliability and performance requirements, specifically th...

  6. Control and acquisition software complex for TBTS experiments

    CERN Document Server

    Dubrovskiy, Alexey

    2010-01-01

    The Two-beam Test-stand (TBTS) is a test area in the CLIC Test Facility (CTF3) to demonstrate the high power RF extraction and acceleration at a high accelerating gradient, which are feasibility issues for the Compact Linear Collider (CLIC) project. In order to achieve an efficient data collection, an acquisition and logging software system was developed. All year round these systems store the main parameters such as beam position, beam current, vacuum level, pulse length etc. For predefined events they also gather and store all information about the last several pulses and the machine status. A GUI interface allows from anywhere to plot many logged characteristics at a maximum of 10 minutes delay, to go though all events and to extract any logged data. A control interface configures actions and long-term control procedures for conditioning accelerating structures. The flexible configuration of the logging, the acquisition and the control systems are integrated into the same GUI. After two years operation the...

  7. Federated software defined network operations for LHC experiments

    Science.gov (United States)

    Kim, Dongkyun; Byeon, Okhwan; Cho, Kihyeon

    2013-09-01

    The most well-known high-energy physics collaboration, the Large Hadron Collider (LHC), which is based on e-Science, has been facing several challenges presented by its extraordinary instruments in terms of the generation, distribution, and analysis of large amounts of scientific data. Currently, data distribution issues are being resolved by adopting an advanced Internet technology called software defined networking (SDN). Stability of the SDN operations and management is demanded to keep the federated LHC data distribution networks reliable. Therefore, in this paper, an SDN operation architecture based on the distributed virtual network operations center (DvNOC) is proposed to enable LHC researchers to assume full control of their own global end-to-end data dissemination. This may achieve an enhanced data delivery performance based on data traffic offloading with delay variation. The evaluation results indicate that the overall end-to-end data delivery performance can be improved over multi-domain SDN environments based on the proposed federated SDN/DvNOC operation framework.

  8. Yellow sticky, PHP software for an electronic brainstorming experiment.

    Energy Technology Data Exchange (ETDEWEB)

    Dornburg, Courtney C.; Stevens, Susan Marie; Davidson, George S.; Forsythe, James Chris

    2007-09-01

    A web-based brainstorm was conducted in the summer of 2007 within the Sandia Restricted Network. This brainstorming experiment was modeled around the 'yellow sticky' brainstorms that are used in many face-to-face meetings at Sandia National Laboratories. This document discusses the implementation and makes suggestions for future implementations.

  9. Social Software: Participants' Experience Using Social Networking for Learning

    Science.gov (United States)

    Batchelder, Cecil W.

    2010-01-01

    Social networking tools used in learning provides instructional design with tools for transformative change in education. This study focused on defining the meanings and essences of social networking through the lived common experiences of 7 college students. The problem of the study was a lack of learner voice in understanding the value of social…

  10. Servicing HEP experiments with a complete set of ready integreated and configured common software components

    CERN Document Server

    Roiser, S; Perrin, Y; Kruzelecki, K

    2010-01-01

    The LCG Applications Area at CERN provides basic software components for the LHC experiments such as ROOT, POOL, COOL which are developed in house and also a set of "external" software packages (70) which are needed in addition such as Python, Boost, Qt, CLHEP, etc. These packages target many different areas of HEP computing such as data persistency, math, simulation, grid computing, databases, graphics, etc. Other packages provide tools for documentation, debugging, scripting languages and compilers. All these packages are provided in a consistent manner on different compilers, architectures and operating systems. The Software Process and Infrastructure project (SPI) [1] is responsible for the continous testing, coordination, release and deployment of these software packages. The main driving force for the actions carried out by SPI are the needs of the LHC experiments, but also other HEP experiments could profit from the set of consistent libraries provided and receive a stable and well tested foundation to...

  11. Metronome LKM: An open source virtual keyboard driver to measure experiment software latencies.

    Science.gov (United States)

    Garaizar, Pablo; Vadillo, Miguel A

    2017-10-01

    Experiment software is often used to measure reaction times gathered with keyboards or other input devices. In previous studies, the accuracy and precision of time stamps has been assessed through several means: (a) generating accurate square wave signals from an external device connected to the parallel port of the computer running the experiment software, (b) triggering the typematic repeat feature of some keyboards to get an evenly separated series of keypress events, or (c) using a solenoid handled by a microcontroller to press the input device (keyboard, mouse button, touch screen) that will be used in the experimental setup. Despite the advantages of these approaches in some contexts, none of them can isolate the measurement error caused by the experiment software itself. Metronome LKM provides a virtual keyboard to assess an experiment's software. Using this open source driver, researchers can generate keypress events using high-resolution timers and compare the time stamps collected by the experiment software with those gathered by Metronome LKM (with nanosecond resolution). Our software is highly configurable (in terms of keys pressed, intervals, SysRq activation) and runs on 2.6-4.8 Linux kernels.

  12. THE IMPACT OF MARKETING EXPERIMENTS ON THE RELATIONSHIP BETWEEN SOFTWARE PRODUCERS AND THEIR RETAILERS

    Directory of Open Access Journals (Sweden)

    HERȚANU ANDREEA

    2013-07-01

    Full Text Available This paper presents the results of a marketing experiment done on the Romanian software market. The main purpose of this research is to determine how the marketing campaigns of software manufacturers can influence the decisions of software retailers. Through this marketing experimental research an evaluation and an analysis of the impact that marketing policies of software companies have on the retailers from all over the country is made. Three different marketing campaigns were proposed to three groups of software vendors from the most important cities of the country. The total number of software retailers included in this experiment is of 45, and the marketing campaigns proposed by the authors in this experiment refer to the Microsoft brand. Promotion strategies such as: sales promotion by encouraging sales force and promotional pricing or even the policy of partner relationship management have a great impact on three aspects regarding software retailers: loyalty, purchase and resale intention and attitude towards a brand. The results of the experiment show a high interest for the strategy of promotional pricing. The representatives of the software vendors have a positive orientation towards sales promotion by encouraging sales force. Regarding the influences of the manipulations used in the experiment, the greatest impact on the loyalty of the software vendors it has the strategy of promotional pricing. Also the policy of sales promotion by encouraging sales force has the biggest impact on the purchase and sale intention of the software retailers. All three manipulations have also an impact on the attitude towards a brand of the vendors, but the differences are too small to determine which of the proposed stimuli has a greater impact on this aspect. The results of the experiment may help and could have a great influence on the future marketing decisions of manufacturers regarding the strategies and marketing policies used on the Romanian

  13. Initial Experience With Neuroendoscopic Surgery In West Africa ...

    African Journals Online (AJOL)

    Initial Experience With Neuroendoscopic Surgery In West Africa. ... African Journal of Neurological Sciences ... Introduction Neuroendoscopic surgery is commonly utilized for the management of intracranial cystic lesions, hydrocephalus, tumor resections and biopsies and for all types of microsurgical procedures that can ...

  14. INTERNATIONAL EXPERIENCE OF THE ECONOMIC SIMULATION SOFTWARE USAGE IN EDUCATION

    Directory of Open Access Journals (Sweden)

    Dmytro Antoniuk

    2016-03-01

    Full Text Available The article describes the research of foreign business simulation usage experience within courses of MBA programs, higher education institutions, as a part of scientific researches and also as a platform for competitions and championships. Development of the information and communication technologies that causes decrease of business simulation purchasing, development and support expenses, gives a chance to expect business simulations usage spreading and expanding to the other potential usage domains. Business simulation development and usage area dynamics enables to conduct tendencies analysis of the market and work out the hypothesis regarding potential new business simulations usage areas. Additionally, business simulation market leaders’ products and services development and adjustments observation is proved to be possible and necessary. Exact business simulations usage examples at the foreign higher education institutions and business schools are described. Systematization of the studied and described business simulations has been performed. Besides, business simulations are proved to be effective for complementing traditional teaching methods and supporting the different domain specialists’ economic competencies development. Foreign experience of the business simulation usage may help to build the basement for the implementation of this learning and scientific research tool at the educational and scientific institution in Ukraine

  15. The ATLAS online High Level Trigger framework experience reusing offline software components in the ATLAS trigger

    CERN Document Server

    Wiedenmann, W

    2009-01-01

    Event selection in the Atlas High Level Trigger is accomplished to a large extent by reusing software components and event selection algorithms developed and tested in an offline environment. Many of these offline software modules are not specifically designed to run in a heavily multi-threaded online data flow environment. The Atlas High Level Trigger (HLT) framework based on the Gaudi and Atlas Athena frameworks, forms the interface layer, which allows the execution of the HLT selection and monitoring code within the online run control and data flow software. While such an approach provides a unified environment for trigger event selection across all of Atlas, it also poses strict requirements on the reused software components in terms of performance, memory usage and stability. Experience of running the HLT selection software in the different environments and especially on large multi-node trigger farms has been gained in several commissioning periods using preloaded Monte Carlo events, in data taking peri...

  16. Building and Sustaining Citywide Afterschool Initiatives: Experiences of the Cross-Cities Network Citywide Afterschool Initiatives.

    Science.gov (United States)

    Hall, Georgia; Harvey, Brooke

    This paper highlights the experiences of several citywide after school initiatives from the Cross-Cities Network, describing activities and strategies that contributed to building operational and sustainable citywide delivery of out-of-school time programs. The paper presents evidence of success and notes lessons learned, identifying key elements…

  17. Experiment and numerical modeling of asymmetrically initiated hexagonal prism warhead

    Directory of Open Access Journals (Sweden)

    Yuan Li

    2017-01-01

    Full Text Available Traditional fragmentation warheads are usually initiated on the axis, producing a uniform fragment distribution around the warhead, but only little portion of them can be imposed on the targets. The aimable warhead, on the other hand, using the off-axis initiations or the structure deforming, can improve the warhead energy utilization highly. Seeking methods to both enhance the fragment velocity and density has significant value for improving the target damage probability. In this article, a warhead shaped as hexagonal prism was studied using arena experiment and numerical modeling and compared with the traditional cylindrical structure. The fragment velocities and target hit patterns of the two types of warheads under axial initiation and asymmetrical initiation are obtained. It is revealed that for the hexagonal prism warhead, the asymmetrical initiation can enhance the fragment velocities by 27.71% and enhance fragment density by 34.09% compared to the axial initiation. The fragment velocity enhancement is close to that of the cylindrical warhead, but the fragment density enhancement is far above the cylindrical warhead. This indicates that the asymmetrically initiated hexagonal prism warhead is a very effective aimable warhead.

  18. Summary of the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1

    Directory of Open Access Journals (Sweden)

    Daniel S Katz

    2014-07-01

    Full Text Available Challenges related to development, deployment, and maintenance of reusable software for science are becoming a growing concern. Many scientists’ research increasingly depends on the quality and availability of software upon which their works are built. To highlight some of these issues and share experiences, the First Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE1 was held in November 2013 in conjunction with the SC13 Conference. The workshop featured keynote presentations and a large number (54 of solicited extended abstracts that were grouped into three themes and presented via panels. A set of collaborative notes of the presentations and discussion was taken during the workshop. Unique perspectives were captured about issues such as comprehensive documentation, development and deployment practices, software licenses and career paths for developers. Attribution systems that account for evidence of software contribution and impact were also discussed. These include mechanisms such as Digital Object Identifiers, publication of “software papers”, and the use of online systems, for example source code repositories like GitHub. This paper summarizes the issues and shared experiences that were discussed, including cross-cutting issues and use cases. It joins a nascent literature seeking to understand what drives software work in science, and how it is impacted by the reward systems of science. These incentives can determine the extent to which developers are motivated to build software for the long-term, for the use of others, and whether to work collaboratively or separately. It also explores community building, leadership, and dynamics in relation to successful scientific software.

  19. Software Engineering Researchers' Attitudes on Case Studies and Experiments : an Exploratory Survey

    NARCIS (Netherlands)

    Tofan, Dan; Galster, Matthias; Avgeriou, Paris; Weyns, Danny

    2011-01-01

    Background: Case studies and experiments are research methods frequently applied in empirical software engineering. Experiments are well-­understood and their value as an empirical method is recognized. On the other hand, there seem to be different opinions on what constitutes a case study, and

  20. Quality assurance for CORAL and COOL within the LCG software stack for the LHC experiments

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    CORAL and COOL are software packages used by the LHC experiments for managing different categories of physics data using a variety of relational database technologies. The core components are written in C++, but Python bindings are also provided. CORAL is a generic relational access layer, while COOL includes the implementation of a specific relational data model and optimization of SQL queries for "conditions data". The software is the result of more than 10 years of development in colaboration between the IT department and the LHC experiments. The packages are built and released within the LCG software stack, for which automatic nightly builds and release installations are provided by PH-SFT (cmake, jenkins, cdash) for many different platforms, compilers and software version configurations. Test-driven development and functional tests of both C++ and Python components (CppUnit, unittest) have been key elements in the success of the projects. Dedicated test suites have also been prepared to commission and ma...

  1. Experience report on using object-oriented design for software maintenance

    OpenAIRE

    Schneidewind, Norman F.

    2007-01-01

    The article of record as published may be found at http://dx.doi.org/10.1002/smr We experimented with modifying the existing object-oriented (OO) design and C++ code of a software reliability model. Our purpose was to assess the efficacy of OO methods for performing maintenance on mathematical software, using a real-world system (NASA Space Shuttle flight software) to illustrate the approach. In this process, we used variants of UML diagrams to modify our design.We found that alth...

  2. Report on the Third Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE3

    Directory of Open Access Journals (Sweden)

    Daniel S. Katz

    2016-10-01

    Full Text Available This report records and discusses the Third Workshop on Sustainable Software for Science: Practice and Experiences (WSSSPE3. The report includes a description of the keynote presentation of the workshop, which served as an overview of sustainable scientific software. It also summarizes a set of lightning talks in which speakers highlighted to-the-point lessons and challenges pertaining to sustaining scientific software. The final and main contribution of the report is a summary of the discussions, future steps, and future organization for a set of self-organized working groups on topics including developing pathways to funding scientific software; constructing useful common metrics for crediting software stakeholders; identifying principles for sustainable software engineering design; reaching out to research software organizations around the world; and building communities for software sustainability. For each group, we include a point of contact and a landing page that can be used by those who want to join that group’s future activities. The main challenge left by the workshop is to see if the groups will execute these activities that they have scheduled, and how the WSSSPE community can encourage this to happen.

  3. Efficiency of Software Testing Techniques: A Controlled Experiment Replication and Network Meta-analysis

    Directory of Open Access Journals (Sweden)

    Omar S. Gómez

    2017-07-01

    Full Text Available Background: Common approaches to software verification include static testing techniques, such as code reading, and dynamic testing techniques, such as black-box and white-box testing. Objective: With the aim of gaining a~better understanding of software testing techniques, a~controlled experiment replication and the synthesis of previous experiments which examine the efficiency of code reading, black-box and white-box testing techniques were conducted. Method: The replication reported here is composed of four experiments in which instrumented programs were used. Participants randomly applied one of the techniques to one of the instrumented programs. The outcomes were synthesized with seven experiments using the method of network meta-analysis (NMA. Results: No significant differences in the efficiency of the techniques were observed. However, it was discovered the instrumented programs had a~significant effect on the efficiency. The NMA results suggest that the black-box and white-box techniques behave alike; and the efficiency of code reading seems to be sensitive to other factors. Conclusion: Taking into account these findings, the Authors suggest that prior to carrying out software verification activities, software engineers should have a~clear understanding of the software product to be verified; they can apply either black-box or white-box testing techniques as they yield similar defect detection rates.

  4. From project-oriented to service-oriented software development: an industrial experience guided by a service reference model

    National Research Council Canada - National Science Library

    Kalinowski, Marcos; Biffl, Stefan; Spínola, Rodrigo Oliveira; Reinehr, Sheila

    2014-01-01

    ...-neutral project-oriented software deliveries.This article reports on the industrial experience of restructuring the supplier-side software development process into a value-based service-oriented format, guided by a service reference model...

  5. Effective UI The Art of Building Great User Experience in Software

    CERN Document Server

    Anderson, Jonathan; Wilson, Robb

    2010-01-01

    People expect effortless, engaging interaction with desktop and web applications, but producing software that generates enjoyable user experiences is much harder than many companies anticipate. With Effective UI, you'll learn proven user-experience strategies that will satisfy your clients and customers, drive business value, and increase brand strength. This book shows you how to capture the collaborative and cooperative spirit among designers, engineers, and management required for building engaging software. You'll also learn valuable methods for maintaining focus throughout the process -

  6. Agile methods in biomedical software development: a multi-site experience report

    Science.gov (United States)

    Kane, David W; Hohman, Moses M; Cerami, Ethan G; McCormick, Michael W; Kuhlmman, Karl F; Byrd, Jeff A

    2006-01-01

    Background Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully used agile development approaches to create and maintain biomedical software, including software for bioinformatics. This paper reports on a qualitative study of our experiences using these methods. Results We have found that agile methods are well suited to the exploratory and iterative nature of scientific inquiry. They provide a robust framework for reproducing scientific results and for developing clinical support systems. The agile development approach also provides a model for collaboration between software engineers and researchers. We present our experience using agile methodologies in projects at six different biomedical software development organizations. The organizations include academic, commercial and government development teams, and included both bioinformatics and clinical support applications. We found that agile practices were a match for the needs of our biomedical projects and contributed to the success of our organizations. Conclusion We found that the agile development approach was a good fit for our organizations, and that these practices should be applicable and valuable to other biomedical software development efforts. Although we found differences in how agile methods were used, we were also able to identify a set of core practices that were common to all of the groups, and that could be a focus for others seeking to adopt these methods. PMID:16734914

  7. Agile methods in biomedical software development: a multi-site experience report

    Directory of Open Access Journals (Sweden)

    Kuhlmman Karl F

    2006-05-01

    Full Text Available Abstract Background Agile is an iterative approach to software development that relies on strong collaboration and automation to keep pace with dynamic environments. We have successfully used agile development approaches to create and maintain biomedical software, including software for bioinformatics. This paper reports on a qualitative study of our experiences using these methods. Results We have found that agile methods are well suited to the exploratory and iterative nature of scientific inquiry. They provide a robust framework for reproducing scientific results and for developing clinical support systems. The agile development approach also provides a model for collaboration between software engineers and researchers. We present our experience using agile methodologies in projects at six different biomedical software development organizations. The organizations include academic, commercial and government development teams, and included both bioinformatics and clinical support applications. We found that agile practices were a match for the needs of our biomedical projects and contributed to the success of our organizations. Conclusion We found that the agile development approach was a good fit for our organizations, and that these practices should be applicable and valuable to other biomedical software development efforts. Although we found differences in how agile methods were used, we were also able to identify a set of core practices that were common to all of the groups, and that could be a focus for others seeking to adopt these methods.

  8. PsyToolkit: a software package for programming psychological experiments using Linux.

    Science.gov (United States)

    Stoet, Gijsbert

    2010-11-01

    PsyToolkit is a set of software tools for programming psychological experiments on Linux computers. Given that PsyToolkit is freely available under the Gnu Public License, open source, and designed such that it can easily be modified and extended for individual needs, it is suitable not only for technically oriented Linux users, but also for students, researchers on small budgets, and universities in developing countries. The software includes a high-level scripting language, a library for the programming language C, and a questionnaire presenter. The software easily integrates with other open source tools, such as the statistical software package R. PsyToolkit is designed to work with external hardware (including IoLab and Cedrus response keyboards and two common digital input/output boards) and to support millisecond timing precision. Four in-depth examples explain the basic functionality of PsyToolkit. Example 1 demonstrates a stimulus-response compatibility experiment. Example 2 demonstrates a novel mouse-controlled visual search experiment. Example 3 shows how to control light emitting diodes using PsyToolkit, and Example 4 shows how to build a light-detection sensor. The last two examples explain the electronic hardware setup such that they can even be used with other software packages.

  9. Initial results of the CD-1 reliable multicast experiment

    Energy Technology Data Exchange (ETDEWEB)

    Agarwal, D. [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Stead, R. [Science Applications International Corporation. (SAIC), Tysons Corner, VA (United States); Coan, B. [Telecordia Technologies. Piscataway Township, NJ (United States); Burns, J. E. [Telecordia Technologies. Piscataway Township, NJ (United States); Shah, N. [Telecordia Technologies. Piscataway Township, NJ (United States); Kyriakopoulos, N. [George Washington Univ., Washington, DC (United States)

    2000-09-29

    During the past year, an experiment has been underway to test use of reliable multicast capabilities for transmission of continuous data in the Global Communication Infrastructure. For the experiment a version of the CD-1 protocol was multicast enabled. The experiment has demonstrated the feasibility of transmitting data in a multicast mode over the GCI. In the case of the Comprehensive Nuclear Test-Ban Treaty the sender could be the station and the receivers the International Data Center (IDC) and one or more National Data Centers (NDC). The potential advantages of multicasting include (a) the timely receipt of the data by the IDC and the host NDC and (b) the simultaneous availability of the raw station data at, at least, two locations. The latter, by introducing redundant data paths, decreases the probability of loss of station data due to a potential failure of a single data receiver. This experiment is only one element of a needed more thorough assessment of the reliability and cost-effectiveness of introducing redundancies in the data transmission paths and the data sinks of the IMS. The next stage of the multicast experiment planned is installation of the multicast-enabled CD-1 software at the GERES IMS station, at the German NDC and at the IDC for further experiments with actual IMS station data. This stage of the experiment is waiting on installation of a GCI link to the German NDC. Negotiations regarding price for this installation have been on going between the Global Communication Infrastructure (GCI) contractor and the German NDC with no resolution. Current development of the CD-x protocol is proceeding in two complementary directions. Along with the work on a multicast enabled version of CD-1 there is also work to develop CD-1.1, which will add end-to-end reliability to the CD-1 protocol among other things. A possible future activity would be to combine the reliable multicast and the end-to-end reliability mechanisms into one CD-x protocol version.

  10. Dynamic crack initiation toughness : experiments and peridynamic modeling.

    Energy Technology Data Exchange (ETDEWEB)

    Foster, John T.

    2009-10-01

    This is a dissertation on research conducted studying the dynamic crack initiation toughness of a 4340 steel. Researchers have been conducting experimental testing of dynamic crack initiation toughness, K{sub Ic}, for many years, using many experimental techniques with vastly different trends in the results when reporting K{sub Ic} as a function of loading rate. The dissertation describes a novel experimental technique for measuring K{sub Ic} in metals using the Kolsky bar. The method borrows from improvements made in recent years in traditional Kolsky bar testing by using pulse shaping techniques to ensure a constant loading rate applied to the sample before crack initiation. Dynamic crack initiation measurements were reported on a 4340 steel at two different loading rates. The steel was shown to exhibit a rate dependence, with the recorded values of K{sub Ic} being much higher at the higher loading rate. Using the knowledge of this rate dependence as a motivation in attempting to model the fracture events, a viscoplastic constitutive model was implemented into a peridynamic computational mechanics code. Peridynamics is a newly developed theory in solid mechanics that replaces the classical partial differential equations of motion with integral-differential equations which do not require the existence of spatial derivatives in the displacement field. This allows for the straightforward modeling of unguided crack initiation and growth. To date, peridynamic implementations have used severely restricted constitutive models. This research represents the first implementation of a complex material model and its validation. After showing results comparing deformations to experimental Taylor anvil impact for the viscoplastic material model, a novel failure criterion is introduced to model the dynamic crack initiation toughness experiments. The failure model is based on an energy criterion and uses the K{sub Ic} values recorded experimentally as an input. The failure model

  11. Introduction to the KWALON Experiment: Discussions on Qualitative Data Analysis Software by Developers and Users

    Directory of Open Access Journals (Sweden)

    Jeanine C. Evers

    2010-11-01

    Full Text Available In this introduction to the KWALON Experiment and related conference, we describe the motivations of the collaborating European networks in organising this joint endeavour. The KWALON Experiment consisted of five developers of Qualitative Data Analysis (QDA software analysing a dataset regarding the financial crisis in the time period 2008-2009, provided by the conference organisers. Besides this experiment, researchers were invited to present their reflective papers on the use of QDA software. This introduction gives a description of the experiment, the "rules", research questions and reflective points, as well as a full description of the dataset and search rules used, and our reflection on the lessons learned. The related conference is described, as are the papers which are included in this FQS issue. URN: http://nbn-resolving.de/urn:nbn:de:0114-fqs1101405

  12. Potential errors when fitting experience curves by means of spreadsheet software

    NARCIS (Netherlands)

    van Sark, W.G.J.H.M.|info:eu-repo/dai/nl/074628526; Alsema, E.A.|info:eu-repo/dai/nl/073416258

    2010-01-01

    Progress ratios (PRs) are widely used in forecasting development of many technologies; they are derived from historical data represented in experience curves. Fitting the double logarithmic graphs is easily done with spreadsheet software like Microsoft Excel, by adding a trend line to the graph.

  13. Experiences from Measuring Learning and Performance in Large-Scale Distributed Software Development

    OpenAIRE

    Britto, Ricardo; Šmite, Darja; Lars-Ola, Damm

    2016-01-01

    Background: Developers and development teams in large-scale software development are often required to learn continuously. Organizations also face the need to train and support new developers and teams on-boarded in ongoing projects. Although learning is associated with performance improvements, experience shows that training and learning does not always result in a better performance or significant improvements might take too long. Aims: In this paper, we report our experiences from establis...

  14. Experimental test accelerator: description and results of initial experiments

    Energy Technology Data Exchange (ETDEWEB)

    Fessenden, T.; Birx, D.; Briggs, R.

    1980-06-02

    The ETA is a high current (10,000 Amp) linear induction accelerator that produces short (30 ns) pulses of electrons at 5 MeV twice per second or in bursts of 5 pulses separated by as little as one millisecond. At this time the machine has operated at 65% of its design current and 90% of the design voltage. This report contains a description of the accelerator and its diagnostics; the results of the initial year of operation; a comparison of design codes with experiments on beam transport; and a discussion of some of the special problems and their status.

  15. An application of the IMC software to controller design for the JPL LSCL Experiment Facility

    Science.gov (United States)

    Zhu, Guoming; Skelton, Robert E.

    1993-01-01

    A software package which Integrates Model reduction and Controller design (The IMC software) is applied to design controllers for the JPL Large Spacecraft Control Laboratory Experiment Facility. Modal Cost Analysis is used for the model reduction, and various Output Covariance Constraints are guaranteed by the controller design. The main motivation is to find the controller with the 'best' performance with respect to output variances. Indeed it is shown that by iterating on the reduced order design model, the controller designed does have better performance than that obtained with the first model reduction.

  16. Initial operation of the Lockheed Martin T4B experiment

    Science.gov (United States)

    Garrett, M. L.; Blinzer, A.; Ebersohn, F.; Gucker, S.; Heinrich, J.; Lohff, C.; McGuire, T.; Montecalvo, N.; Raymond, A.; Rhoads, J.; Ross, P.; Sommers, B.; Strandberg, E.; Sullivan, R.; Walker, J.

    2017-10-01

    The T4B experiment is a linear, encapsulated ring cusp confinement device, designed to develop a physics and technology basis for a follow-on high beta (β 1) machine. The experiment consists of 13 magnetic field coils (11 external, 2 internal), to produce a series of on-axis field nulls surrounded by modest magnetic fields of up to 0.3 T. The primary plasma source used on T4B is a lanthanum hexaboride (LaB6) cathode, capable of coupling over 100 kW into the plasma. Initial testing focused on commissioning of components and integration of diagnostics. Diagnostics include both long and short wavelength interferometry, bolometry, visible and X-ray spectroscopy, Langmuir and B-dot probes, Thomson scattering, flux loops, and fast camera imagery. Low energy discharges were used to begin validation of physics models and simulation efforts. Following the initial machine check-out, neutral beam injection (NBI) was integrated onto the device. Detailed results will be presented. 2017 Lockheed Martin Corporation. All Rights Reserved.

  17. Scaffolding Students’ Initial Self-Access Language Centre Experiences

    Directory of Open Access Journals (Sweden)

    Robert Croker

    2012-09-01

    Full Text Available As the number of self-access language centres (SALCs in Japanese universities continues to grow, so too does the challenge of successfully introducing them to first-year university students, whose initial experiences of self-access language learning may otherwise be confusing and even unsettling. One approach is to carefully scaffold students’ first SALC encounters by connecting them with their classroom learning experiences. This paper discusses one such approach developed at a private university in central Japan, which was based upon a two-stage ‘push-pull’ ‘materials-light, people-focused’ strategy. Teachers initially ‘pushed’ their students to visit the SALC by giving them speaking ‘homework’ to be done there. The SALC then also offered interesting interactive events designed to ‘pull’ learners to continue to come. These push-pull activities could be done with few or no materials, and emphasized interaction with people rather than materials. This two-stage, push-pull strategy served as a bridge between the language classroom and a SALC, helping learners make the first steps in their transition from being a ‘classroom English learner’ to becoming a ‘SALC English user’.

  18. Novalis frameless image-guided noninvasive radiosurgery: initial experience.

    Science.gov (United States)

    Wurm, Reinhard E; Erbel, Stephan; Schwenkert, Isabel; Gum, Franz; Agaoglu, Daniel; Schild, Reinhard; Schlenger, Lorenz; Scheffler, Dirk; Brock, Mario; Budach, Volker

    2008-05-01

    To evaluate our initial experience with Novalis (BrainLAB, Heimstetten, Germany) frameless image-guided noninvasive radiosurgery. The system combines the dedicated Novalis linear accelerator with ExacTrac X-Ray 6D, an infrared camera and a kilovolt stereoscopic x-ray imaging system, a noninvasive mask system, and ExacTrac robotics for patient positioning in six degrees of freedom. Reference cranial skeletal structures are radiographically imaged and automatically fused to digital reconstructed radiographs calculated from the treatment planning computed tomographic scan to find the target position and accomplish automatic real-time tracking before and during radiosurgery. We present the acceptance testing and initial experience in 15 patients with 19 intracranial lesions treated between December 2005 and June 2006 at the Charité by frameless image-guided radiosurgery with doses between 12 and 20 Gy prescribed to the target-encompassing isodose. Phantom tests showed an overall system accuracy of 1.04 +/- 0.47 mm, with an average in-plane deviation of 0.02 +/- 0.96 mm for the x-axis and 0.02 +/- 0.70 mm for the y-axis. After infrared-guided patient setup of all patients, the overall average translational deviation determined by stereoscopic x-ray verification was 1.5 +/- 1.3 mm, and the overall average rotational deviation was 1.0 +/- 0.8 degree. The data used for radiosurgery, after stereoscopic x-ray verification and correction, demonstrated an overall average setup error of 0.31 +/- 0.26 mm for translation and 0.26 +/- 0.23 degree for rotation. This initial evaluation demonstrates the system accuracy and feasibility of Novalis image-guided noninvasive radiosurgery for intracranial benign and malignant lesions.

  19. Developing Control and Monitoring Software for the Data Acquisition System of the COMPASS Experiment at CERN

    Directory of Open Access Journals (Sweden)

    Martin Bodlák

    2013-01-01

    Full Text Available This paper focuses on the analysis, design and development of software for the new data acquisition system of the COMPASS experiment at CERN. In this system, the data flow is controlled by custom hardware; the software will therefore be used only for run control and for monitoring. The requirements on the software have been analyzed, and the functionality of the system has been defined. The system consists of several distributed nodes; communication between the nodes is based on a custom protocol and a DIM library. A minimal version of the system has already been implemented. Preliminary results of performance and stability tests have shown that the system fulfills the defined requirements, and is stable. In the next phase of development, the system will be tested on the real hardware. It is expected that the system will be ready for deployment in 2014.

  20. Developer Initiation and Social Interactions in OSS: A Case Study of the Apache Software Foundation

    Science.gov (United States)

    2014-08-01

    in the context of gamification [43]. Cheng and Vassileva [44] observed “gaming” behav- ior in an educational online community, i.e., incentivizing...newcomers to software development within Microsoft [48]. Their focus was on understanding how science pedagogy prepares students for the workforce. One...transitioning from outsider to insider is called Organizational Socialization, or Onboarding, in the psychology literature [49, 50]. Baur et al. study the

  1. Clinical and practical requirements of online software for anesthesia documentation an experience report.

    Science.gov (United States)

    Benson, M; Junger, A; Quinzio, L; Fuchs, C; Sciuk, G; Michel, A; Marquardt, K; Hempelmann, G

    2000-07-01

    The aim of this paper is the presentation of a new version of the anesthesia documentation software, NarkoData, that has been used in routine clinical work in our department as part of an anesthesia information management system (AIMS) since 1995. The performance of this software is presented along with requirements for future development of such a system. The originally used version, NarkoData 3.0, is an online anesthesia documentation software established by the software company ProLogic GmbH. It was primarily developed as a disk-based system for the MacOS operating system (Apple Computer Inc.). Based on our routine experience with the system, a catalogue of requirements was developed that concentrated on improvement in the sequence of work, administration and data management. In 1996, the concepts developed in our department, in close co-operation with medical personnel and the software company, led to a considerable enlargement of the program functions and the subsequent release of a new version of NarkoData. Since 1997, more than 20 000 anesthesia procedures have been recorded annually with this new version at 115 decentralized work stations at our university hospital.

  2. Organization of the STAR Experiment Software Framework at JINR. Results and Experience from the First Two Years of Work

    CERN Document Server

    Arkhipkin, D A

    2004-01-01

    The organization of STAR experiment software framework at JINR is described. The approach being based on the distributed file system ASF was implemented at the NEOSTAR minicluster at LPP, JINR. An operation principle of the cluster as well as its work description and samples of the performed analysis are also given. The results of the NEOSTAR minicluster performance have demonstrated broad facilities of the distributed computing concept to be employed in experimental data analysis and high-energy physics modeling.

  3. Robust optimal design of experiments for model discrimination using an interactive software tool.

    Directory of Open Access Journals (Sweden)

    Johannes Stegmaier

    Full Text Available Mathematical modeling of biochemical processes significantly contributes to a better understanding of biological functionality and underlying dynamic mechanisms. To support time consuming and costly lab experiments, kinetic reaction equations can be formulated as a set of ordinary differential equations, which in turn allows to simulate and compare hypothetical models in silico. To identify new experimental designs that are able to discriminate between investigated models, the approach used in this work solves a semi-infinite constrained nonlinear optimization problem using derivative based numerical algorithms. The method takes into account parameter variabilities such that new experimental designs are robust against parameter changes while maintaining the optimal potential to discriminate between hypothetical models. In this contribution we present a newly developed software tool that offers a convenient graphical user interface for model discrimination. We demonstrate the beneficial operation of the discrimination approach and the usefulness of the software tool by analyzing a realistic benchmark experiment from literature. New robust optimal designs that allow to discriminate between the investigated model hypotheses of the benchmark experiment are successfully calculated and yield promising results. The involved robustification approach provides maximally discriminating experiments for the worst parameter configurations, which can be used to estimate the meaningfulness of upcoming experiments. A major benefit of the graphical user interface is the ability to interactively investigate the model behavior and the clear arrangement of numerous variables. In addition to a brief theoretical overview of the discrimination method and the functionality of the software tool, the importance of robustness of experimental designs against parameter variability is demonstrated on a biochemical benchmark problem. The software is licensed under the GNU

  4. Implementation of Software Configuration Management Process by Models: Practical Experiments and Learned Lessons

    Directory of Open Access Journals (Sweden)

    Bartusevics Arturs

    2014-12-01

    Full Text Available Nowadays software configuration management process is not only dilemma which system should be used for version control or how to merge changes from one source code branch to other. There are multiple tasks such as version control, build management, deploy management, status accounting, bug tracking and many others that should be solved to support full configuration management process according to most popular quality standards. The main scope of the mentioned process is to include only valid and tested software items to final version of product and prepare a new version as soon as possible. To implement different tasks of software configuration management process, a set of different tools, scripts and utilities should be used. The current paper provides a new model-based approach to implementation of configuration management. Using different models, a new approach helps to organize existing solutions and develop new ones by a parameterized way, thus increasing reuse of solutions. The study provides a general description of new model-based conception and definitions of all models needed to implement a new approach. The second part of the paper contains an overview of criteria, practical experiments and lessons learned from using new models in software configuration management. Finally, further works are defined based on results of practical experiments and lessons learned.

  5. PET/MR imaging of atherosclerosis: initial experience and outlook.

    Science.gov (United States)

    Rischpler, Christoph; Nekolla, Stephan G; Beer, Ambros J

    2013-01-01

    Hybrid scanners such as PET/CT have in the past emerged as a valuable modality in clinical routine as well as an important research tool. Recently, the newly developed fully integrated PET/MR scanners were introduced to the market, raising high expectations especially due to the excellent soft tissue contrast and functional imaging capabilities of MRI. In this issue of the American Journal of Nuclear Medicine and Molecular Imaging, initial experiences using a hybrid PET/MR scanner for carotid artery imaging in a group of patients with increased risk for atherosclerosis are described. This represents a proof-of-principle study, which could stimulate future applications of this powerful modality in atherosclerotic plaque imaging.

  6. Laparoendoscopic single-site urological surgery: initial experience in Japan.

    Science.gov (United States)

    Kawauchi, Akihiro; Kamoi, Kazumi; Soh, Jintetsu; Naitoh, Yasuyuki; Okihara, Koji; Miki, Tsuneharu

    2010-03-01

    The objective of this paper is to report our initial experience in laparoendoscopic single-site surgery (LESS). One patient underwent LESS varicocelectomy and another patient underwent LESS pyeloplasty. The Triport was inserted into the abdomen through the umbilical incision. In the varicocelectomy, testicular vessels were coagulated by a vessel-sealing system, and transected. In the pyeloplasty, a 2-mm needlescopic port was added to facilitate the procedure, and a dismembered procedure was performed. Total operative duration was 60 min for the varicocelectomy and 240 min for the pyeloplasty. Blood loss was minimal and no perioperative complications occurred. At the 3-month follow up, no postoperative complications were observed and there was no complaint of pain. LESS varicocelectomy and pyeloplasty were successfully performed with excellent cosmetic results and no complications.

  7. Monitoring the Laryngeal Nerves During Thyroidectomy. Initial 115 Cases Experience.

    Science.gov (United States)

    Popescu, R; Ponoran, D; Ignat, O; Constantinoiu, S

    2015-01-01

    The lesions of the laryngeal nerves, despite low incidence, are the most severe long term complications after thyroidectomy. Visualization after careful dissection of the recurrent laryngeal nerve (RLN) is now the golden standard among thyroid surgeons. We assessed traditional landmarks for the identification of RLN and anatomic high risk situation. The study also presented our initial experience using neuro monitoring of RLN (IONM) during surgery. The results show a recognizable Zuckerkandl tubercle in 162 of the 222 cases (72,97%). After dissection RLN was found posterior from TZ in 154 cases (95,06%) and lateral from TZ in 8 cases (4,93%). The identification of the Zuckerkandl tubercle is a useful landmark for RLN localization. As concerning high risk situations we found 2 non recurrent laryngeal nerves (both on the right side). Extra laryngeal ramification of RLN is an anatomical reality with significant incidence (23,8% in our study) and major surgical involvement. Extra laryngeal ramification of RLN occurs more often between the cross point with inferior thyroid artery and larynx entry point. Monitoring the branches of RLN we obtain major EMG signal on the anterior one. The surgical meaning is that the anterior branch carries the most important motor fibers and we have to pay extra care in the correct identification and preservation of it. From a total of 222 visually identified RLN we have 215 nerves (96,84%) with positive EMG signal on monitoring. For 7 nerves (3,15%) we had no EMG signal. In 3 cases (2 total thyroidectomies and 1 lobectomy) involving 5 RLN there was a false negative result caused by electrode malposition or desoldering from endotracheal tube. Our initial experience shows that IONM is harmless, easy to handle and a useful tool for identifying the nerve and confirm its integrity. More extended studies are needed to show if intraoperative monitoring decreases the rate of RLN iatrogenic injury. Celsius.

  8. Symetis Acurate Neo transfemoral aortic bioprosthesis - initial Polish experience.

    Science.gov (United States)

    Zembala, Michał; Hawranek, Michał; Wacławski, Jacek; Niklewski, Tomasz; Nadziakiewicz, Paweł; Koba, Rafał; Przybylski, Roman; Walas, Ryszard; Głowacki, Jan; Jazwiec, Tomasz; Garbacz, Marcin; Gąsior, Mariusz; Zembala, Marian

    2016-01-01

    Transcatheter aortic valve implantation (TAVI) has proven to be a valuable alternative to conventional surgical aortic valve replacement in high-risk and surgically inoperable patients who suffer from severe symptomatic aortic stenosis. With the second generation of TAVI devices improvements in both handling and performance are highly demanded. This brief clinical communication reports the first Polish experience with the second generation of transfemoral TAVI device--Symetis Acurate Neo. From November 19th 2014 until February 18th 2015 nine (n = 9) patients with severe symptomatic aortic stenosis have been operated on using the Symetis Acurate Neo. Patients were subject to seven-day evaluation and 30-day phone follow-up. The procedure was safely and successfully performed in all patients. A SMALL (S) valve (21-23 mm equivalent) was used in two patients, MEDIUM valve (M; 23-25 mm equivalent) in five patients, and a LARGE valve (L; 25-26 mm equivalent) in two patients. In three cases post-release balloon dilatation was required. There were no intraoperative complications and no major adverse events (as per VARC classification) during initial hospitalisation, including conduction or rhythm disturbances. In all cases, the mean gradient on the prosthetic valves was 7.8 mm Hg (10.2 mm Hg on the "S" valves). Rapid improvement in patients' functional class was noted. Perivalvular leak was evaluated as "mild" in three cases, "trace" in one, and "not existing" in five. This initial experience with the Symetis Acurate Neo demonstrates its good safety profile and excellent haemodynamics. Low radial stress of the valve results in minimal incidence of atrioventricular rhythm disturbances, and a sealing crown for nearly non-existent paravalvular leak.

  9. Initially curved microplates under electrostatic actuation: theory and experiment

    KAUST Repository

    Saghir, Shahid

    2016-07-01

    Microplates are the building blocks of many micro-electro-mechanical systems. It is common for them to experience initial curvature imperfection due to residual stresses caused by the micro fabrication process. Such plates are essentially different from perfectly flat ones and cannot be modeled using flat plate models. In this paper, we adopt a dynamic analog of the von Karman governing equations of imperfect plates. These equations are then used to develop a reduced order model based on the Galerkin procedure, to simulate the static and dynamic behavior of the microplate under electrostatic actuation. To validate the simulation results, an initially curved imperfect microplate made of silicon nitride is fabricated and tested. The static behaviour of the microplate is investigated when applying a DC voltage Vdc. Then, the dynamic behaviour of the microplate is examined under the application of a harmonic AC voltage, Vac, superimposed to Vdc. The simulation results show good agreement with the experimentally measured responses. © 2016 IOP Publishing Ltd.

  10. THE RELATIONSHIP BETWEEN GENDER AND STUDENTS’ ATTITUDE AND EXPERIENCE of USING A MATHEMATICAL SOFTWARE PROGRAM (MATLAB)

    OpenAIRE

    Mehmet A. OCAK

    2006-01-01

    This correlation study examined the relationship between gender and the students’ attitude and prior knowledge of using one of the mathematical software programs (MATLAB). Participants were selected from one community college, one state university and one private college. Students were volunteers from three Calculus I classrooms (one class from each school) in which MATLAB was used extensively. A survey regarding students’ attitude and experience on using the MATLAB program was administered t...

  11. Affect 4.0: a free software package for implementing psychological and psychophysiological experiments.

    Science.gov (United States)

    Spruyt, Adriaan; Clarysse, Jeroen; Vansteenwegen, Debora; Baeyens, Frank; Hermans, Dirk

    2010-01-01

    We describe Affect 4.0, a user-friendly software package for implementing psychological and psychophysiological experiments. Affect 4.0 can be used to present visual, acoustic, and/or tactile stimuli in highly complex (i.e., semirandomized and response-contingent) sequences. Affect 4.0 is capable of registering response latencies and analog behavioral input with millisecond accuracy. Affect 4.0 is available free of charge.

  12. 5th Workshop on Software and Usability Engineering Cross-Pollination: Patterns, Usability and User Experience

    OpenAIRE

    Forbrig, Peter; Bernhaupt, Regina; Winckler, Marco; Wesson, Janet

    2011-01-01

    Part 1: Long and Short Papers; International audience; The workshop focuses on how process models, methods and knowledge from the area of Human-Computer Interaction can be integrated and adopted to support and enhance traditional software engineering processes. In its 5th edition this workshop will investigate the application of usability engineering methods that are adapted to fit the evaluation of advanced interfaces and how usability and user experience evaluation methods can be incorporat...

  13. Supporting Interdisciplinary Collaboration Through Reusable Free Software. A Research Student Experience

    Science.gov (United States)

    Dimech, C.

    2013-12-01

    In this contribution, I present a critical evaluation of my experience as a research student conducting an interdisciplinary project that bridges the world of geoscience with that of astronomy. The major challenge consists in studying and modifying existing geophysical software to work with synthetic solar data not obtained by direct measurement but useful for testing and evaluation, and data released from the satellite HINODE and the Solar Dynamics Observatory. I have been fortunate to collaborate closely with multiple geoscientists keen to share their software codes and help me understand their implementations so I can extend the methodology to solve problems in solar physics. Moreover, two additional experiences have helped me develop my research and collaborative skills. First was an opportunity to involve an undergraduate student, and secondly, my participation at the GNU Hackers Meeting in Paris. Three aspects that need particular attention to enhance the collective productivity of any group of individuals keen to extend existing codes to achieve further interdisciplinary goals have been identified. (1) The production of easily reusable code that users can study and modify even when large sets of computations are involved. (2) The transformation of solutions into tools that are 100% free software. (3) The harmonisation of collaborative interactions that effectively tackle the two aforementioned tasks. Each one will be discussed in detail during this session based on my experience as a research student.

  14. CoReHA 2.0: A Software Package for In Vivo MREIT Experiments

    Science.gov (United States)

    Jeon, Kiwan

    2013-01-01

    Magnetic resonance electrical impedance tomography (MREIT) is a new medical imaging modality visualizing static conductivity images of electrically conducting subjects. Recently, MREIT has rapidly progressed in its theory, algorithm, and experiment technique and now reached to the stage of in vivo animal experiments. In this paper, we present a software, named CoReHA 2.0 standing for the second version of conductivity reconstructor using harmonic algorithms, to facilitate in vivo MREIT reconstruction of conductivity image. This software offers various computational tools including preprocessing of MREIT data, identification of 2D geometry of the imaging domain and electrode positions, and reconstruction of cross-sectional scaled conductivity images from MREIT data. In particular, in the new version, we added several tools including ramp-preserving denoising, harmonic inpainting, and local harmonic B z algorithm to deal with data from in vivo experiments. The presented software will be useful to researchers in the field of MREIT for simulation, validation, and further technical development. PMID:23509604

  15. Big Science, Small-Budget Space Experiment Package Aka MISSE-5: A Hardware And Software Perspective

    Science.gov (United States)

    Krasowski, Michael; Greer, Lawrence; Flatico, Joseph; Jenkins, Phillip; Spina, Dan

    2007-01-01

    Conducting space experiments with small budgets is a fact of life for many design groups with low-visibility science programs. One major consequence is that specialized space grade electronic components are often too costly to incorporate into the design. Radiation mitigation now becomes more complex as a result of being restricted to the use of commercial off-the-shelf (COTS) parts. Unique hardware and software design techniques are required to succeed in producing a viable instrument suited for use in space. This paper highlights some of the design challenges and associated solutions encountered in the production of a highly capable, low cost space experiment package.

  16. Initial Work on the Characterization of Additive Manufacturing (3D Printing Using Software Image Analysis

    Directory of Open Access Journals (Sweden)

    Jeremy Straub

    2015-04-01

    Full Text Available A current challenge in additive manufacturing (commonly known as 3D printing is the detection of defects. Detection of defects (or the lack thereof in bespoke industrial manufacturing may be safety critical and reduce or eliminate the need for testing of printed objects. In consumer and prototype printing, early defect detection may facilitate the printer taking corrective measures (or pausing printing and alerting a user, preventing the need to re-print objects after the compounding of a small error occurs. This paper considers one approach to defect detection. It characterizes the efficacy of using a multi-camera system and image processing software to assess printing progress (thus detecting completion failure defects and quality. The potential applications and extrapolations of this type of a system are also discussed.

  17. Integrating User eXperience practices into software development processes: implications of the UX characteristics

    Directory of Open Access Journals (Sweden)

    Pariya Kashfi

    2017-10-01

    Full Text Available User eXperience (UX is a key factor in the success of software systems. Many software companies face challenges in their work with UX. Existing research does not analyze UX practices and challenges in relation to other software quality characteristics or, in particular, in relation to usability. A better understanding of these challenges can help researchers and practitioners better address them in the future. In this empirical study, we have interviewed 17 practitioners with different backgrounds and occupations from eight software development companies. Their responses are coded, and analyzed with thematic analysis. We report eight themes of challenges that practitioners face in their work with UX. While some of these challenges partly overlap with those reported in existing literature about usability or other software quality characteristics, the participants of our study either view many of the challenges as unique to UX, or more severe in the case of UX. Although at a superficial level challenges of UX and other quality characteristics overlap, we differentiate these challenges at a deeper level through the five main characteristics of UX: subjective, holistic, dynamic, context-dependent and worthwhile. In particular, we identified that these characteristics have at least 20 implications (i.e. additional difficulties for day-to-day work of practitioners. We found that 11 of these implications have been previously reported in literature. However, to the best of our knowledge, the remaining nine implications are unique to our study. These implications can explain why practitioners perceive the challenges to be more severe than for other quality characteristics. Most importantly, they can explain the industry’s lopsided focus on the pragmatic aspect of UX. Our findings can be useful for researchers in identifying new and industry-relevant research areas and for practitioners to learn from empirically investigated challenges in UX work, and

  18. Sustaining an Online, Shared Community Resource for Models, Robust Open source Software Tools and Data for Volcanology - the Vhub Experience

    Science.gov (United States)

    Patra, A. K.; Valentine, G. A.; Bursik, M. I.; Connor, C.; Connor, L.; Jones, M.; Simakov, N.; Aghakhani, H.; Jones-Ivey, R.; Kosar, T.; Zhang, B.

    2015-12-01

    Over the last 5 years we have created a community collaboratory Vhub.org [Palma et al, J. App. Volc. 3:2 doi:10.1186/2191-5040-3-2] as a place to find volcanology-related resources, and a venue for users to disseminate tools, teaching resources, data, and an online platform to support collaborative efforts. As the community (current active users > 6000 from an estimated community of comparable size) embeds the tools in the collaboratory into educational and research workflows it became imperative to: a) redesign tools into robust, open source reusable software for online and offline usage/enhancement; b) share large datasets with remote collaborators and other users seamlessly with security; c) support complex workflows for uncertainty analysis, validation and verification and data assimilation with large data. The focus on tool development/redevelopment has been twofold - firstly to use best practices in software engineering and new hardware like multi-core and graphic processing units. Secondly we wish to enhance capabilities to support inverse modeling, uncertainty quantification using large ensembles and design of experiments, calibration, validation. Among software engineering practices we practice are open source facilitating community contributions, modularity and reusability. Our initial targets are four popular tools on Vhub - TITAN2D, TEPHRA2, PUFF and LAVA. Use of tools like these requires many observation driven data sets e.g. digital elevation models of topography, satellite imagery, field observations on deposits etc. These data are often maintained in private repositories that are privately shared by "sneaker-net". As a partial solution to this we tested mechanisms using irods software for online sharing of private data with public metadata and access limits. Finally, we adapted use of workflow engines (e.g. Pegasus) to support the complex data and computing workflows needed for usage like uncertainty quantification for hazard analysis using physical

  19. Reducing software security risk through an integrated approach research initiative model based verification of the Secure Socket Layer (SSL) Protocol

    Science.gov (United States)

    Powell, John D.

    2003-01-01

    This document discusses the verification of the Secure Socket Layer (SSL) communication protocol as a demonstration of the Model Based Verification (MBV) portion of the verification instrument set being developed under the Reducing Software Security Risk (RSSR) Trough an Integrated Approach research initiative. Code Q of the National Aeronautics and Space Administration (NASA) funds this project. The NASA Goddard Independent Verification and Validation (IV&V) facility manages this research program at the NASA agency level and the Assurance Technology Program Office (ATPO) manages the research locally at the Jet Propulsion Laboratory (California institute of Technology) where the research is being carried out.

  20. JRTF: A Flexible Software Framework for Real-Time Control in Magnetic Confinement Nuclear Fusion Experiments

    Science.gov (United States)

    Zhang, M.; Zheng, G. Z.; Zheng, W.; Chen, Z.; Yuan, T.; Yang, C.

    2016-04-01

    The magnetic confinement nuclear fusion experiments require various real-time control applications like plasma control. ITER has designed the Fast Plant System Controller (FPSC) for this job. ITER provided hardware and software standards and guidelines for building a FPSC. In order to develop various real-time FPSC applications efficiently, a flexible real-time software framework called J-TEXT real-time framework (JRTF) is developed by J-TEXT tokamak team. JRTF allowed developers to implement different functions as independent and reusable modules called Application Blocks (AB). The AB developers only need to focus on implementing the control tasks or the algorithms. The timing, scheduling, data sharing and eventing are handled by the JRTF pipelines. JRTF provides great flexibility on developing ABs. Unit test against ABs can be developed easily and ABs can even be used in non-JRTF applications. JRTF also provides interfaces allowing JRTF applications to be configured and monitored at runtime. JRTF is compatible with ITER standard FPSC hardware and ITER (Control, Data Access and Communication) CODAC Core software. It can be configured and monitored using (Experimental Physics and Industrial Control System) EPICS. Moreover the JRTF can be ported to different platforms and be integrated with supervisory control software other than EPICS. The paper presents the design and implementation of JRTF as well as brief test results.

  1. [Initial experience in robot-assisted colorectal surgery in Mexico].

    Science.gov (United States)

    Villanueva-Sáenz, Eduardo; Ramírez-Ramírez, Moisés Marino; Zubieta-O'Farrill, Gregorio; García-Hernández, Luis

    Colorectal surgery has advanced notably since the introduction of the mechanical suture and the minimally invasive approach. Robotic surgery began in order to satisfy the needs of the patient-doctor relationship, and migrated to the area of colorectal surgery. An initial report is presented on the experience of managing colorectal disease using robot-assisted surgery, as well as an analysis of the current role of this platform. A retrospective study was conducted in order to review five patients with colorectal disease operated using a robot-assisted technique over one year in the initial phase of the learning curve. Gender, age, diagnosis and surgical indication, surgery performed, surgical time, conversion, bleeding, post-operative complications, and hospital stay, were analysed and described. A literature review was performed on the role of robotic assisted surgery in colorectal disease and cancer. The study included 5 patients, 3 men and 2 women, with a mean age of 62.2 years. Two of them were low anterior resections with colorectal primary anastomoses, one of them extended with a loop protection ileostomy, a Frykman-Goldberg procedure, and two left hemicolectomies with primary anastomoses. The mean operating time was 6hours and robot-assisted 4hours 20minutes. There were no conversions and the mean hospital stay was 5 days. This technology is currently being used worldwide in different surgical centres because of its advantages that have been clinically demonstrated by various studies. We report the first colorectal surgical cases in Mexico, with promising results. There is enough evidence to support and recommend the use of this technology as a viable and safe option. Copyright © 2016 Academia Mexicana de Cirugía A.C. Publicado por Masson Doyma México S.A. All rights reserved.

  2. The German gas hydrate initiative sugar : innovative exploitation techniques, numerical modelling, and laboratory experiments

    Energy Technology Data Exchange (ETDEWEB)

    Haeckel, M. [IFM-GEOMAR, Kiel (Germany)

    2010-07-01

    The German gas hydrate initiative and innovative exploitation techniques, numerical modelling, and laboratory experiments were discussed in this presentation. The main objectives of the sugar project are to model spatial and temporal distribution of sub-seafloor gas hydrates; to constrain major control parameters of hydrate formation; and to develop a new tool for three-dimensional prediction of gas hydrate deposits. The overall purpose is to predict exploitable gas hydrate deposits. Several illustrations were offered, including basin/geological modelling; properties of gas hydrate layers; and nested model/local grid refinement. The future of basin modeling was also discussed with particular reference to testing and calibration of software packages. Options for carbon dioxide storage and methane hydrate exploitation as well as critical issues that needed to be addressed were also outlined. Several reservoir modelling projects were presented. Scenarios and technical concepts were discussed. The presentation concluded with a summary of international co-operation efforts in this area. tabs., figs.

  3. Initial software and data-load procedures for the Navy Occupational Health Information Management Systems (NOHIMS). Final report

    Energy Technology Data Exchange (ETDEWEB)

    Pearsall, D.M.; Hall, T.M.

    1988-05-02

    This document provides step-by-step instructions for installing the Naval Occupational Health Information Management System (NOHIMS) software. It also describes how to create site baseline systems, daily operations and control, communications, and other system software. The following are key objectives of the Navy Occupational Health Information Management System (NOHIMS): 1) Creation of a safer and healthier work environment for Navy employees by providing timely notification of exposure results, rapid retrieval of hazardous-material data, and ensuring proper medical monitoring; 2) Elimination of time-consuming manual recordkeeping methods; 3) Standardization of recordkeeping procedures; 4) Integration of Environmental surveillance and Medical monitoring components of the Navy's Occupational Health Program; and 5) Establishment of a Navy-wide data base for epidemiological studies. The purpose of the Initial Software and Data Load Procedures (ISDLP) is to provide a detailed guide for the NOHIMS implementation team and the system manager. This document will attempt to provide information not covered elsewhere, and will provide additional material in areas that are especially complex.

  4. Radiation Hardening by Software Techniques on FPGAs: Flight Experiment Evaluation and Results

    Science.gov (United States)

    Schmidt, Andrew G.; Flatley, Thomas

    2017-01-01

    We present our work on implementing Radiation Hardening by Software (RHBSW) techniques on the Xilinx Virtex5 FPGAs PowerPC 440 processors on the SpaceCube 2.0 platform. The techniques have been matured and tested through simulation modeling, fault emulation, laser fault injection and now in a flight experiment, as part of the Space Test Program- Houston 4-ISS SpaceCube Experiment 2.0 (STP-H4-ISE 2.0). This work leverages concepts such as heartbeat monitoring, control flow assertions, and checkpointing, commonly used in the High Performance Computing industry, and adapts them for use in remote sensing embedded systems. These techniques are extremely low overhead (typically radiation hardened processor. The recently concluded STP-H4 flight experiment was an opportunity to upgrade the RHBSW techniques for the Virtex5 FPGA and demonstrate them on-board the ISS to achieve TRL 7. This work details the implementation of the RHBSW techniques, that were previously developed for the Virtex4-based SpaceCube 1.0 platform, on the Virtex5-based SpaceCube 2.0 flight platform. The evaluation spans the development and integration with flight software, remotely uploading the new experiment to the ISS SpaceCube 2.0 platform, and conducting the experiment continuously for 16 days before the platform was decommissioned. The experiment was conducted on two PowerPCs embedded within the Virtex5 FPGA devices and the experiment collected 19,400 checkpoints, processed 253,482 status messages, and incurred 0 faults. These results are highly encouraging and future work is looking into longer duration testing as part of the STP-H5 flight experiment.

  5. Overview of Keda Torus eXperiment initial results

    Science.gov (United States)

    Liu, Wandong; Lan, Tao; Mao, Wenzhe; Li, Hong; Xie, Jinlin; Liu, Ahdi; Wan, Shude; Wang, Hai; Zheng, Jian; Wen, Xiaohui; Zhou, Haiyang; You, Wei; Li, Chenguang; Bai, Wei; Tu, Cui; Tan, Mingsheng; Luo, Bing; Fu, Chenshuo; Huang, Fangcheng; Xu, Hangqi; Deng, Tijian; Zhu, Junfeng; Zhang, Sen; Adil, Yolbarsop; Hu, Jintong; Xiao, Bingjia; Luo, Zhengping; Wang, Huazhong; Shen, Biao; Fu, Peng; Yang, Lei; Song, Yuntao; Yang, Qingxi; Zheng, Jinxing; Xu, Hao; Zhang, Ping; Xiao, Chijin; Ding, Weixing

    2017-11-01

    The Keda Torus eXperiment (KTX) is a new reversed field pinch (RFP) device at the University of Science and Technology of China. The construction and assembly of KTX, including the vacuum chamber, conducting shell, magnetic field windings, power supply system, active control coils, vacuum pump and data acquisition system, have been completed on August 1, 2015. Immediately following that, the first plasma was obtained on August 15, 2015. Intensive conditioning of the machine is underway to ramp up the plasma current toward its full operation. An active feedback mode control system has been built and has been implemented to control the error field around the vertical gaps of the conducting shell. The pulsed power supply systems of ohmic heating field and toroidal field (TF), using thyristor and energy storage capacitors, have been tested and commissioned. The TF power supply has flexibility in being able to operate with a reversed TF configuration and stable TF configuration. The fundamental diagnostic tools are developed for early KTX operation. Currently, the plasma current is up to 205 kA and the maximum discharge length is 21 ms, approaching to the conducting shell penetration time. Furthermore, typical RFP discharges are being produced with RFP state lasting 2 ms. These initial operation results for KTX are described in detail.

  6. Initial experience in total laparoscopic central pancreatectomy with pancreatogastrostomy.

    Science.gov (United States)

    Jiang, Chong Yi; Wang, Wei

    2015-03-01

    Central pancreatectomy is an ideal treatment option to preserve pancreatic parenchyma and function for the benign and low-grade malignant tumors limited to the pancreatic neck or proximal body of the pancreas. This study presents our initial experience in total laparoscopic central pancreatectomy with pancreatogastrostomy. In 2013, two consecutive patients underwent total laparoscopic central pancreatectomy at our hospital. Data on surgical procedure, post-operative course, and follow-up were evaluated. Both the patients successfully underwent total laparoscopic central pancreatectomy with pancreatogastrostomy. The operating times were 250 and 300 min with blood loss of 100 and 200 ml and post-operative hospital stay of 9 and 10 days, respectively. The first patient did not suffer any post-operative complications. The second patient developed intra-abdominal fluid collection due to pancreatic fistula which was managed by percutaneous drainage. These two patients had no post-operative diabetes mellitus or exocrine insufficiency within the follow-up periods of 14 and 10 months, respectively. Thus, laparoscopic CP is a safe and feasible technique for treating benign and low-grade malignant tumors in the neck or proximal body of the pancreas when performed by highly skilled pancreatic and laparoscopic surgeons.

  7. Initial Experience with the Machine Protection System for LHC

    CERN Document Server

    Schmidt, Ruediger; Dehning, Bernd; Ferro-Luzzi, Massimiliano; Goddard, Brennan; Lamont, Mike; Siemko, Andrzej; Uythoven, Jan; Wenninger, Jorg; Zerlauth, Markus

    2010-01-01

    For nominal beam parameters at 7 TeV/c each proton beam with a stored energy of 362 MJ threatens to damage accelerator equipment in case of uncontrolled beam loss. These parameters will only be reached after some years of operation, however, a small fraction of this energy is already sufficient to damage accelerator equipment or experiments. The correct functioning of the machine protection systems is vital during the different operational phases already for initial operation. When operating the complex magnet system, with and without beam, safe operation relies on the protection and interlock systems for the superconducting circuits. For safe injection and transfer of the beams from SPS to LHC, transfer line parameters are monitored, beam absorbers must be in the correct position and the LHC must be ready to accept beam. At the end of a fill and in case of failures beams must be properly extracted onto the dump blocks, for some types of failure within less than few hundred microseconds. Safe operation requir...

  8. Software R&D for Next Generation of HEP Experiments, Inspired by Theano

    CERN Multimedia

    CERN. Geneva

    2015-01-01

    In the next decade, the frontiers of High Energy Physics (HEP) will be explored by three machines: the High Luminosity Large Hadron Collider (HL-LHC) in Europe, the Long Base Neutrino Facility (LBNF) in the US, and the International Linear Collider (ILC) in Japan. These next generation experiments must address two fundamental problems in the current generation of HEP experimental software: the inability to take advantage and adapt to the rapidly evolving processor landscape, and the difficulty in developing and maintaining increasingly complex software systems by physicists. I will propose a strategy, inspired by the automatic optimization and code generation in Theano, to simultaneously address both problems. I will describe three R&D projects with short-term physics deliverables aimed at developing this strategy. The first project is to develop maximally sensitive General Search for New Physics at the LHC by applying the Matrix Element Method running GPUs of HPCs. The second is to classify and reconstru...

  9. The Data Quality Monitoring Software for the CMS experiment at the LHC

    CERN Document Server

    AUTHOR|(CDS)2071602

    2014-01-01

    The Data Quality Monitoring (DQM) Software is a central tool in the CMS experiment. Its flexibility allows for integration in several key environments Online, for real-time detector monitoring; Offline, for the final, fine-grained Data Certification; Release-Validation, to constantly validate the functionalities and the performance of the reconstruction software; in Monte Carlo productions.Since the end of data taking at a center of mass energy of 8 TeV, the environment in which the DQM lives has undergone fundamental changes. In turn, the DQM system has made significant upgrades in many areas to respond to not only the changes in infrastructure, but also the growing specialized needs of the collaboration with an emphasis on more sophisticated methods for evaluating dataquality, as well as advancing the DQM system to provide quality assessments of various Monte Carlo simulations versus data distributions, monitoring changes in physical effects due to modifications of algorithms or framework, and enabling reg...

  10. USER'S GUIDE: Strategic Waste Minimization Initiative (SWAMI) Version 2.0 - A Software Tool to Aid in Process Analysis for Pollution Prevention

    Science.gov (United States)

    The Strategic WAste Minimization Initiative (SWAMI) Software, Version 2.0 is a tool for using process analysis for identifying waste minimization opportunities within an industrial setting. The software requires user-supplied information for process definition, as well as materia...

  11. THE RELATIONSHIP BETWEEN GENDER AND STUDENTS’ ATTITUDE AND EXPERIENCE of USING A MATHEMATICAL SOFTWARE PROGRAM (MATLAB

    Directory of Open Access Journals (Sweden)

    Mehmet A. OCAK

    2006-04-01

    Full Text Available This correlation study examined the relationship between gender and the students’ attitude and prior knowledge of using one of the mathematical software programs (MATLAB. Participants were selected from one community college, one state university and one private college. Students were volunteers from three Calculus I classrooms (one class from each school in which MATLAB was used extensively. A survey regarding students’ attitude and experience on using the MATLAB program was administered to classes. The findings of the study indicated that gender differences are not related to students’ attitude and experience on the program. The results revealed slightly positive correlation between and students’ attitude and experience on the program. The implications of this study shows that teachers who use MATLAB in their instruction and classroom practices must pay attention on how much students use it, the obstacles students had to overcome to succeed in its use, and their general issues and concerns regarding MATLAB use.

  12. DAQ Software Contributions, Absolute Scale Energy Calibration and Background Evaluation for the NOvA Experiment at Fermilab

    Energy Technology Data Exchange (ETDEWEB)

    Flumerfelt, Eric Lewis [Univ. of Tennessee, Knoxville, TN (United States)

    2015-08-01

    The NOvA (NuMI Off-axis ve [nu_e] Appearance) Experiment is a long-baseline accelerator neutrino experiment currently in its second year of operations. NOvA uses the Neutrinos from the Main Injector (NuMI) beam at Fermilab, and there are two main off-axis detectors: a Near Detector at Fermilab and a Far Detector 810 km away at Ash River, MN. The work reported herein is in support of the NOvA Experiment, through contributions to the development of data acquisition software, providing an accurate, absolute-scale energy calibration for electromagnetic showers in NOvA detector elements, crucial to the primary electron neutrino search, and through an initial evaluation of the cosmic background rate in the NOvA Far Detector, which is situated on the surface without significant overburden. Additional support work for the NOvA Experiment is also detailed, including DAQ Server Administration duties and a study of NOvA’s sensitivity to neutrino oscillations into a “sterile” state.

  13. Percutaneous MR-guided cryoablation of prostate cancer: initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Gangi, Afshin; Tsoumakidou, Georgia; Abdelli, Omar; Buy, Xavier [University Hospital of Strasbourg, Department of Interventional Radiology, Strasbourg (France); Mathelin, Michel de [University of Strasbourg, Lsiit, Strasbourg (France); Jacqmin, Didier; Lang, Herve [University Hospital of Strasbourg, Department of Urology, Strasbourg (France)

    2012-08-15

    We report our initial experience and the technical feasibility of transperineal prostate cryoablation under MR guidance. Percutaneous MR-guided cryoablation was performed in 11 patients with prostatic adenocarcinoma contraindicated for surgery (mean age: 72 years, mean Gleason score: 6.45, mean prostate-specific antigen (PSA): 6.21 ng/ml, T1-2c/N0/M0, mean: prostate volume 36.44 ml). Free-hand probe positioning was performed under real-time MR imaging. Four to seven cryoprobes were inserted into the prostate, depending on gland volume. The ice ball was monitored using real-time and high-resolution BLADE multi-planar imaging. Patients were followed at 1, 3, 6, 9 and 12 months after the procedure with serum PSA level and post-ablation MRI. Prostate cryoablation was technically feasible in 10/11 patients. The ice ball was clearly and sharply visualised in all cases as a signal-void area. Mean ice-ball volume was 53.3 ml. Mean follow-up was 15 months (range: 1-25). Mean PSA nadir was 0.33 ng/ml (range: 0.02-0.94 ng/ml). Mean hospitalisation was 5 days (range: 3-13). Complications included a urethro-rectal fistula, urinary infection, transient dysuria and scrotal pain. MR-guided prostate cryoablation is feasible and promising, with excellent monitoring of the ice ball. Future perspectives could include the use of MR guidance for focal prostate cancer cryotherapy. (orig.)

  14. XDesign: an open-source software package for designing X-ray imaging phantoms and experiments.

    Science.gov (United States)

    Ching, Daniel J; Gürsoy, Dogˇa

    2017-03-01

    The development of new methods or utilization of current X-ray computed tomography methods is impeded by the substantial amount of expertise required to design an X-ray computed tomography experiment from beginning to end. In an attempt to make material models, data acquisition schemes and reconstruction algorithms more accessible to researchers lacking expertise in some of these areas, a software package is described here which can generate complex simulated phantoms and quantitatively evaluate new or existing data acquisition schemes and image reconstruction algorithms for targeted applications.

  15. ATLAS Experience with HEP Software at the Argonne Leadership Computing Facility

    CERN Document Server

    LeCompte, T; The ATLAS collaboration; Benjamin, D

    2014-01-01

    A number of HEP software packages used by the ATLAS experiment, including GEANT4, ROOT and ALPGEN, have been adapted to run on the IBM Blue Gene supercomputers at the Argonne Leadership Computing Facility. These computers use a non-x86 architecture and have a considerably less rich operating environment than in common use in HEP, but also represent a computing capacity an order of magnitude beyond what ATLAS is presently using via the LCG. The status and potential for making use of leadership-class computing, including the status of integration with the ATLAS production system, is discussed.

  16. The Data Quality Monitoring Software for the CMS experiment at the LHC

    Science.gov (United States)

    Rovere, M.

    2015-12-01

    The Data Quality Monitoring (DQM) Software is a central tool in the CMS experiment. Its flexibility allows for integration in several key environments: Online, for real-time detector monitoring; Offline, for the final, fine-grained data analysis and certification; Release-Validation, to constantly validate the functionality and the performance of the reconstruction software; in Monte Carlo productions. Since the end of data taking at a center of mass energy of 8 TeV, the environment in which the DQM lives has undergone fundamental changes. In turn, the DQM system has made significant upgrades in many areas to respond to not only the changes in infrastructure, but also the growing specialized needs of the collaboration with an emphasis on more sophisticated methods for evaluating data quality, as well as advancing the DQM system to provide quality assessments of various Monte Carlo simulations versus data distributions, monitoring changes in physical effects due to modifications of algorithms or framework, and enabling regression modeling for long-term effects for the CMS detector. The central tool to deliver Data Quality information is an interactive web site for browsing data quality histograms (DQMGUI). In this contribution the usage of the DQM Software in the different environments and its integration in the CMS Reconstruction Software Framework (CMSSW) and in all production workflows are presented, with emphasis on recent developments and improvement in advance of the LHC restart at 13 TeV. The main technical challenges and the adopted solutions to them will be also discussed with emphasis on functionality and long-term robustness.

  17. Software and experience with managing workflows for the computing operation of the CMS experiment

    Science.gov (United States)

    Vlimant, Jean-Roch; CMS Collaboration

    2017-10-01

    We present a system deployed in the summer of 2015 for the automatic assignment of production and reprocessing workflows for simulation and detector data in the frame of the Computing Operation of the CMS experiment at the CERN LHC. Processing requests involves a number of steps in the daily operation, including transferring input datasets where relevant and monitoring them, assigning work to computing resources available on the CMS grid, and delivering the output to the Physics groups. Automation is critical above a certain number of requests to be handled, especially in the view of using more efficiently computing resources and reducing latency. An effort to automatize the necessary steps for production and reprocessing recently started and a new system to handle workflows has been developed. The state-machine system described consists in a set of modules whose key feature is the automatic placement of input datasets, balancing the load across multiple sites. By reducing the operation overhead, these agents enable the utilization of more than double the amount of resources with robust storage system. Additional functionality were added after months of successful operation to further balance the load on the computing system using remote read and additional resources. This system contributed to reducing the delivery time of datasets, a crucial aspect to the analysis of CMS data. We report on lessons learned from operation towards increased efficiency in using a largely heterogeneous distributed system of computing, storage and network elements.

  18. Experience with highly-parallel software for the storage system of the ATLAS Experiment at CERN

    CERN Document Server

    Colombo, T; The ATLAS collaboration

    2012-01-01

    The ATLAS experiment is observing proton-proton collisions delivered by the LHC accelerator at a centre of mass energy of 7 TeV. The ATLAS Trigger and Data Acquisition (TDAQ) system selects interesting events on-line in a three-level trigger system in order to store them at a budgeted rate of several hundred Hz, for an average event size of ~1.2 MB. This paper focuses on the TDAQ data-logging system and in particular on the implementation and performance of a novel SW design, reporting on the effort of exploiting the full power of recently installed multi-core hardware. In this respect, the main challenge presented by the data-logging workload is the conflict between the largely parallel nature of the event processing, especially the recently introduced on-line event-compression, and the constraint of sequential file writing and checksum evaluation. This is furtherly complicated by the necessity of operating in a fully data-driven mode, to cope with continuously evolving trigger and detector configurations. T...

  19. The MGDO software library for data analysis in Ge neutrinoless double-beta decay experiments

    CERN Document Server

    Agostini, M; Finnerty, P; Kröninger, K; Lenz, D; Liu, J; Marino, M G; Martin, R; Nguyen, K D; Pandola, L; Schubert, A G; Volynets, O; Zavarise, P

    2011-01-01

    The GERDA and Majorana experiments will search for neutrinoless double-beta decay of germanium-76 using isotopically enriched high-purity germanium detectors. Although the experiments differ in conceptual design, they share many aspects in common, and in particular will employ similar data analysis techniques. The collaborations are jointly developing a C++ software library, MGDO, which contains a set of data objects and interfaces to encapsulate, store and manage physical quantities of interest, such as waveforms and high-purity germanium detector geometries. These data objects define a common format for persistent data, whether it is generated by Monte Carlo simulations or an experimental apparatus, to reduce code duplication and to ease the exchange of information between detector systems. MGDO also includes general-purpose analysis tools that can be used for the processing of measured or simulated digital signals. The MGDO design is based on the Object-Oriented programming paradigm and is very flexible, a...

  20. Experience of using an open source clinical trials data management software system in Kenya.

    Science.gov (United States)

    Ngari, Moses M; Waithira, Naomi; Chilengi, Roma; Njuguna, Patricia; Lang, Trudie; Fegan, Greg

    2014-11-26

    Clinical trials data management (CTDM) remains one of the many challenges in running state of the art trials in resource-poor settings since most trials do not allocate, or have available, sufficient resources for CTDM and because of poor internet connectivity. Open-source software like OpenClinica could be a solution in such scenarios. In 2007, the KEMRI-Wellcome Trust Research Programme (KWTRP) adopted OpenClinica (OC) community edition, an open-source software system and we share our experience and lessons learnt since its adoption. We have used OC in three different modes; direct remote data entry from sites through Global System for Mobile Communications (GSM) modems, a centralized data centre approach where all data from paper records were entered at a central location and an off-line approach where data entry was done from a copy of database hosted on a field-site server laptop, then data uploaded to a centralized server later. We have used OC in eleven trials/studies with a cumulative number of participants in excess of 6000. These include large and complex trials, with multiple sites recruiting in different regions of East Africa. In the process, we have developed substantial local capacity through hands-on training and mentorship, which we have now begun to share with other institutions in the region. Our experience demonstrates that an open source data management system to manage trials' data can be utilized to international industry standards in resource-poor countries.

  1. Data Acquisition Software for Experiments at the MAMI-C Tagged Photon Facility

    Science.gov (United States)

    Oussena, Baya; Annand, John

    2013-10-01

    Tagged-photon experiments at Mainz use the electron beam of the MAMI (Mainzer MIcrotron) accelerator, in combination with the Glasgow Tagged Photon Spectrometer. The AcquDAQ DAQ system is implemented in the C + + language and makes use of CERN ROOT software libraries and tools. Electronic hardware is characterized in C + + classes, based on a general purpose class TDAQmodule and implementation in an object-oriented framework makes the system very flexible. The DAQ system provides slow control and event-by-event readout of the Photon Tagger, the Crystal Ball 4-pi electromagnetic calorimeter, central MWPC tracker and plastic-scintillator, particle-ID systems and the TAPS forward-angle calorimeter. A variety of front-end controllers running Linux are supported, reading data from VMEbus, FASTBUS and CAMAC systems. More specialist hardware, based on optical communication systems and developed for the COMPASS experiment at CERN, is also supported. AcquDAQ also provides an interface to configure and control the Mainz programmable trigger system, which uses FPGA-based hardware developed at GSI. Currently the DAQ system runs at data rates of up to 3MB/s and, with upgrades to both hardware and software later this year, we anticipate a doubling of that rate. This work was supported in part by the U.S. DOE Grant No. DE-FG02-99ER41110.

  2. High Level Trigger software performance profiling and $\\chi_{b}$ production study at the LHCb experiment

    CERN Document Server

    Mazurov, Alexander; Dijkstra, Hans

    Trigger is a crucial item in experiments at hadron colliders. In this thesis, a software profiling tool has been developed, which helps to analyze and improve the performance of the High Level Trigger software of the LHCb experiment. This tool is able to identify spots where the execution time of the trigger application is slow, thereby allowing the optimization of the trigger decision speed and minimizing dead times during data taking. The highly efficient LHCb trigger allows precision studies of decays of heavy flavoured particles in final states with muons. In this thesis, a study of $\\chi_b$ production at LHCb is performed on a proton-proton collisions data set, corresponding to 3 fb$^{-1}$ integrated luminosity, collected at center-of-mass energies of $\\sqrt{s}$=7 and 8 TeV. Radiative $\\chi_b$ transitions to $\\Upsilon(1S)$, $\\Upsilon(2S)$ and $\\Upsilon(3S)$ are reconstructed, where the $\\Upsilon(nS)$, indicated generally as $\\Upsilon$ in the following, decays in two muon. The fraction of $\\Upsilon$ origi...

  3. Software-Based Wireless Power Transfer Platform for Various Power Control Experiments

    Directory of Open Access Journals (Sweden)

    Sun-Han Hwang

    2015-07-01

    Full Text Available In this paper, we present the design and evaluation of a software-based wireless power transfer platform that enables the development of a prototype involving various open- and closed-loop power control functions. Our platform is based on a loosely coupled planar wireless power transfer circuit that uses a class-E power amplifier. In conjunction with this circuit, we implement flexible control functions using a National Instruments Data Acquisition (NI DAQ board and algorithms in the MATLAB/Simulink. To verify the effectiveness of our platform, we conduct two types of power-control experiments: a no-load or metal detection using open-loop power control, and an output voltage regulation for different receiver positions using closed-loop power control. The use of the MATLAB/Simulink software as a part of the planar wireless power transfer platform for power control experiments is shown to serve as a useful and inexpensive alternative to conventional hardware-based platforms.

  4. Tracer: a general-purpose software library for logging events in computerized experiments.

    Science.gov (United States)

    Lahl, Olaf; Pietrowsky, Reinhard

    2008-11-01

    In certain areas of the behavioral sciences, such as cognitive and perceptual psychology, researchers may choose to have their experiments partially or completely driven by software programs, which instruct and guide subjects through the sequence of tasks. Despite distinct advantages of unattended trial execution, on frequent occasions, experimenters may desire to keep track of the progress or to be notified of certain events, such as when the subject has completed a task. The Tracer software library presented here is a lightweight Windows programming interface that provides experimenters the ability to trace events and status notifications on one or more remote computers and log files. With only a few lines of additional code or script code, researchers can monitor the real-time progress of one or more unattended experiments running on remote computers of the local area network or the Internet. This article describes the functionality and usage of the Tracer library. The Tracer binaries, include files, sample code, and documentation files may be downloaded from the Psychonomic Society Archive of Norms, Stimuli, and Data at www.psychonomic.org/archive.

  5. Professional Experience as a Wicked Problem in Initial Teacher Education

    Science.gov (United States)

    Southgate, Erica; Reynolds, Ruth; Howley, Peter

    2013-01-01

    Professional experience in teacher education is explored through the conceptual lens of the wicked problem. Wicked problems are socially constructed and complex. This paper outlines what is at stake in the framing of the problem of professional experience and how constructions of the problem make it difficult to find enduring solutions. The…

  6. Informal Science: Family Education, Experiences, and Initial Interest in Science

    Science.gov (United States)

    Dabney, Katherine P.; Tai, Robert H.; Scott, Michael R.

    2016-01-01

    Recent research and public policy have indicated the need for increasing the physical science workforce through development of interest and engagement with informal and formal science, technology, engineering, and mathematics experiences. This study examines the association of family education and physical scientists' informal experiences in…

  7. Results of 1 year of clinical experience with independent dose calculation software for VMAT fields

    Directory of Open Access Journals (Sweden)

    Juan Fernando Mata Colodro

    2014-01-01

    Full Text Available It is widely accepted that a redundant independent dose calculation (RIDC must be included in any treatment planning verification procedure. Specifically, volumetric modulated arc therapy (VMAT technique implies a comprehensive quality assurance (QA program in which RIDC should be included. In this paper, the results obtained in 1 year of clinical experience are presented. Eclipse from Varian is the treatment planning system (TPS, here in use. RIDC were performed with the commercial software; Diamond ® (PTW which is capable of calculating VMAT fields. Once the plan is clinically accepted, it is exported via Digital Imaging and Communications in Medicine (DICOM to RIDC, together with the body contour, and then a point dose calculation is performed, usually at the isocenter. A total of 459 plans were evaluated. The total average deviation was -0.3 ± 1.8% (one standard deviation (1SD. For higher clearance the plans were grouped by location in: Prostate, pelvis, abdomen, chest, head and neck, brain, stereotactic radiosurgery, lung stereotactic body radiation therapy, and miscellaneous. The highest absolute deviation was -0.8 ± 1.5% corresponding to the prostate. A linear fit between doses calculated by RIDC and by TPS produced a correlation coefficient of 0.9991 and a slope of 1.0023. These results are very close to those obtained in the validation process. This agreement led us to consider this RIDC software as a valuable tool for QA in VMAT plans.

  8. [Initial clinical experiences with the fast digital picture of roentgen transmission profiles in the human (the chronogram)].

    Science.gov (United States)

    Hübener, K H; Metzger, H O; Kalender, W

    1982-06-01

    By means of suitable hardware and software changes it becomes possible to obtain transmission profiles of high time resolution (up to 50 profiles/sec) with the help of a CT device which is suitable for the recording of digital radiographs, in one transversal body layer. In this manner, it becomes possible to measure changes in the density profile from 6 up to 50 sec and to analyse them. This method called "Chronogram", enables high-resolution recording of density changes, similar to kymography. The possibilities of using contrast media are demonstrated by means of phantom measurements, and initial clinical experiences are outlined on the basis of practical examples.

  9. Propriedade Intelectual em Software: o que podemos apreender da experiência internacional?

    Directory of Open Access Journals (Sweden)

    Arlan Souza

    2007-01-01

    Full Text Available Este artigo, elaborado no âmbito de um grupo de estudos sobre propriedade intelectual (PI em tecnologias da informação e sensíveis,1 analisa a questão do regime de proteção do programa de computador no Brasil à luz das experiências européia e norte-americana. A revisão da evolução da legislação internacional e brasileira bem como seus efeitos práticos sobre a proteção dos programas de computador revelam que as mudanças tecnológicas nas tecnologias da informação vêm levantando dilemas complexos no âmbito legal em todo o mundo. Nos Estados Unidos, a legislação é mais flexível, privilegiando os interesses das empresas de software. Já na União Européia a maior diversidade de atores é um entrave para o desenvolvimento de uma diretiva regional. O Brasil segue as regras do Acordo TRIPS e também enfrenta muitas dificuldades para harmonizar o estímulo ao desenvolvimento tecnológico com condutas que promovam o benefício econômico e social.This paper reviews the legal framework for intellectual property protection for software as a product in the USA, European Union and Brazil. Rapid technological change in the world software industry poses new challenges for existing intellectual property regimes. The USA has responded with a flexible interpretation of property rights which in fact favors the software industry. In the European Union, the larger heterogeneity of actors and interests resulted in a fail in the attempt to approve a unified directive. Brazil follows the rules agreed in the TRIPS but also faces difficulties for harmonizing incentives for innovation with conducts which head to social and economic development.

  10. EnviroNET: Space environment for Strategic Defense Initiative experiments

    Science.gov (United States)

    Lauriente, Michael

    1989-01-01

    EnviroNET is an operational system available to the Strategic Defense Initiative (SDI) experimenters who have access to a terminal or dial-up port. It is a tail node on Space Physics Analysis Network (SPAN) accessible directly or through the national networks via NPSS. Some of the benefits to using EnviroNET include: validated NASA environmental information and interactive space models; facilitating the payload integration process; easy access to expert assistance; and potential for time and cost savings.

  11. CT guided percutaneous needle biopsy of the chest: initial experience

    African Journals Online (AJOL)

    The objective of this article is to report our first experience of CT guided percutaneous thoracic biopsy and to demonstrate the accuracy and safety of this procedure. This was a retrospective study of 28 CT-Guided Percutaneous Needle Biopsies of the Chest performed on 24 patients between November 2014 and April 2015.

  12. Initial Experience with Bevacizumab (Avastin ) in the Treatment of ...

    African Journals Online (AJOL)

    PROF SABE NWOSU

    of Neovascular Age-related Macular Degeneration in Nigerian. Patients. SNN Nwosu. Guinness Eye Center Onitsha. SUMMARY. Objective: To report on the early experience with the treatment of neovascular AMD with intravitreal injection of bevacizumab. (Avastin) in Nigeria. Materials and Methods: Eight eyes (7 patients) ...

  13. KITSAT-1 Cosmic Ray Experiment-Initial Results

    Directory of Open Access Journals (Sweden)

    K. W. Min

    1993-12-01

    Full Text Available The KITSAT-1 was successfully launched on August 11, 1992, into a near circular, 1300-km-high orbit with an 66 deg inclination. The satellite carries a solid state detector module to measure the high energy particle flux originating mostly from the inner radiation belt. We describe here the objectives of the experiment, the detector structure, and the preliminary result.

  14. Initial experience of buccal mucosa urethroplasty in Tanzania ...

    African Journals Online (AJOL)

    Objective: To present the experience with the use of buccal mucosa graft urethroplasty. Patients and methods: This was a retrospective review of 53 consecutive patients who presented with urethral strictures seen by the author from January 2002 to December 2003 and were managed with different forms of urethral ...

  15. Control for Uterine Fibroid Embolisation- An Initial Experience in ...

    African Journals Online (AJOL)

    Uterine fibroid embolisation (UFE) generates moderate to severe post-procedural pain. We present a case series of 24 patients who underwent UFE during our first experience in managing the sometimes excruciating pain that accompanies embolisation of the uterine arteries. We also show the evolution of our protocol for ...

  16. FDG PET/MR in initial staging of sarcoma: Initial experience and comparison with conventional imaging.

    Science.gov (United States)

    Platzek, Ivan; Beuthien-Baumann, Bettina; Schramm, Georg; Maus, Jens; Laniado, Michael; Kotzerke, Jörg; van den Hoff, Jörg; Schuler, Markus

    To assess the feasibility of positron emission tomography/magnetic resonance imaging (PET/MR) with 18F-fluordeoxyglucose (FDG) for initial staging of sarcoma. Twenty-nine patients with sarcoma were included in this study. Weighted kappa (κ) was used to assess the agreement between PET/MR and conventional imaging (CT and MR). The accuracy of PET/MR and conventional imaging for distant metastases was compared using receiver operating characteristic (ROC) analysis. T and M stage were identical for PET/MR and conventional modalities in all patients (κ=1). N stage was identical for 28/29 patients (κ=0.65). FDG PET/MR shows excellent agreement with the currently preferred imaging methods (CT and MR) in initial staging of sarcoma. Copyright © 2016 Elsevier Inc. All rights reserved.

  17. Contrast-enhanced ultrasound in ovarian tumors – diagnostic parameters: method presentation and initial experience

    Science.gov (United States)

    MAXIM, ANITA-ROXANA; BADEA, RADU; TAMAS, ATILLA; TRAILA, ALEXANDRU

    2013-01-01

    The aim of this paper is to discuss and illustrate the use of contrast-enhanced ultrasound in evaluating ovarian tumors compared to conventional ultrasound, Doppler ultrasound and the histopathological analysis and suggest how this technique may best be used to distinguish benign from malignant ovarian masses. We present the method and initial experience of our center by analyzing the parameters used in contrast-enhanced ultrasound in 6 patients with ovarian tumors of uncertain etiology. For examination we used a Siemens ultrasound machine with dedicated contrast software and the contrast agent SonoVue, Bracco. The patients underwent conventional ultrasound, Doppler ultrasound and i.v. administration of the contrast agent. The parameters studied were: inflow of contrast (rise time), time to peak enhancement, mean transit time. The series of patients is part of an extensive prospective PhD study aimed at elaborating a differential diagnosis protocol for benign versus malignant ovarian tumors, by validating specific parameters for contrast-enhanced ultrasound. Although the method is currently used with great success in gastroenterology, urology and senology, its validation in gynecology is still in the early phases. Taking into consideration that the method is minimally invasive and much less costly that CT/MRI imaging, demonstrating its utility in oncologic gynecology would be a big step in preoperative evaluation of these cases. PMID:26527912

  18. Initial Experience of Utilizing Real-Time Intra-Procedural PET/CT Biopsy.

    Science.gov (United States)

    Aparici, Carina Mari; Aslam, Rizwan; Win, Aung Zaw

    2014-01-01

    Nonreal-time Positron Emission Tomography/Computed Tomography (PET/CT) biopsies that use the image co-registration of a prior PET with an intra-procedural CT have been reported. The aim of this study was to report the initial experience of performing real-time intra-procedural PET/CT-guided biopsies. All patients (n = 4) had a prior PET/CT examination of the concerning lesion and no significant CT correlate. On the day of the biopsy, 5 mCi of 18F-fluorodeoxyglucose (FDG) or NaF18 was intravenously injected. After 60 min of biodistribution of the molecular probe, PET/CT images were obtained in a limited one bed position over the region of the concerning lesion to be biopsied. One patient had a mesenteric mass and the other three had bone lesions, one located in the rib and two in the iliac bone. The pathology report revealed that two lesions (50%) were malignant and two lesions (50%) were benign. The results of the biopsy changed management in all cases. There was 0% complication rate. No additional software or hardware is required to perform real-time intra-procedural PET/CT-guided biopsies. It can optimize the yield, especially in cases where there are no anatomical abnormalities. Real-time intra-procedural PET/CT biopsy may have benefits over conventional biopsy techniques in terms of accuracy.

  19. Initial Experience of Utilizing Real-Time Intra-Procedural PET/CT Biopsy

    Directory of Open Access Journals (Sweden)

    Carina Mari Aparici

    2014-01-01

    Full Text Available Objectives: Nonreal-time Positron Emission Tomography/Computed Tomography (PET/CT biopsies that use the image co-registration of a prior PET with an intra-procedural CT have been reported. The aim of this study was to report the initial experience of performing real-time intra-procedural PET/CT-guided biopsies. Materials and Methods: All patients (n = 4 had a prior PET/CT examination of the concerning lesion and no significant CT correlate. On the day of the biopsy, 5 mCi of 18F-fluorodeoxyglucose (FDG or NaF18 was intravenously injected. After 60 min of biodistribution of the molecular probe, PET/CT images were obtained in a limited one bed position over the region of the concerning lesion to be biopsied. Results: One patient had a mesenteric mass and the other three had bone lesions, one located in the rib and two in the iliac bone. The pathology report revealed that two lesions (50% were malignant and two lesions (50% were benign. The results of the biopsy changed management in all cases. There was 0% complication rate. Conclusions: No additional software or hardware is required to perform real-time intra-procedural PET/CT-guided biopsies. It can optimize the yield, especially in cases where there are no anatomical abnormalities. Real-time intra-procedural PET/CT biopsy may have benefits over conventional biopsy techniques in terms of accuracy.

  20. Unique High Energy Experiment Initiative by ICSP with Weather Balloons

    Science.gov (United States)

    Chakrabarti, S. K.; Bhowmick, D.; Sarkar, R.; Bhattacharyya, A.; Midya, S.

    2015-09-01

    With the advent of miniaturization of instruments, Indian Centre for Space Physics began exploring high energy Universe using weather balloons about six years ago. Several Payloads of mass within 4 kg have been flown to near space. Along with the main measurement unit which is usually a scintillator detector, attitude measurement unit, GPS tracking unit, video camera and parachute(s) are also flown. Using large duration flights unique to ICSP without using any valve or ballast and any extra cost, this inexpensive initiative brings back very rich scientific data on soft X-ray spectra of Cosmic Rays, Solar flares, Gamma Ray Bursts and Crab Pulsar. Some results are presented. The payloads are reusable, reducing the recurring cost per flight to be less that $500.00.

  1. Cardiac biplane strain imaging: initial in vivo experience

    Science.gov (United States)

    Lopata, R. G. P.; Nillesen, M. M.; Verrijp, C. N.; Singh, S. K.; Lammens, M. M. Y.; van der Laak, J. A. W. M.; van Wetten, H. B.; Thijssen, J. M.; Kapusta, L.; de Korte, C. L.

    2010-02-01

    In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (heart were recorded during the cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve (Δp: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy (Δp = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values.

  2. Cardiac biplane strain imaging: initial in vivo experience

    Energy Technology Data Exchange (ETDEWEB)

    Lopata, R G P; Nillesen, M M; Thijssen, J M; De Korte, C L [Clinical Physics Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Verrijp, C N; Lammens, M M Y; Van der Laak, J A W M [Department of Pathology, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Singh, S K; Van Wetten, H B [Department of Cardiothoracic Surgery, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands); Kapusta, L [Pediatric Cardiology, Department of Pediatrics, Radboud University Nijmegen Medical Centre, Nijmegen (Netherlands)], E-mail: R.Lopata@cukz.umcn.nl

    2010-02-21

    In this study, first we propose a biplane strain imaging method using a commercial ultrasound system, yielding estimation of the strain in three orthogonal directions. Secondly, an animal model of a child's heart was introduced that is suitable to simulate congenital heart disease and was used to test the method in vivo. The proposed approach can serve as a framework to monitor the development of cardiac hypertrophy and fibrosis. A 2D strain estimation technique using radio frequency (RF) ultrasound data was applied. Biplane image acquisition was performed at a relatively low frame rate (<100 Hz) using a commercial platform with an RF interface. For testing the method in vivo, biplane image sequences of the heart were recorded during the cardiac cycle in four dogs with an aortic stenosis. Initial results reveal the feasibility of measuring large radial, circumferential and longitudinal cumulative strain (up to 70%) at a frame rate of 100 Hz. Mean radial strain curves of a manually segmented region-of-interest in the infero-lateral wall show excellent correlation between the measured strain curves acquired in two perpendicular planes. Furthermore, the results show the feasibility and reproducibility of assessing radial, circumferential and longitudinal strains simultaneously. In this preliminary study, three beagles developed an elevated pressure gradient over the aortic valve ({delta}p: 100-200 mmHg) and myocardial hypertrophy. One dog did not develop any sign of hypertrophy ({delta}p = 20 mmHg). Initial strain (rate) results showed that the maximum strain (rate) decreased with increasing valvular stenosis (-50%), which is in accordance with previous studies. Histological findings corroborated these results and showed an increase in fibrotic tissue for the hearts with larger pressure gradients (100, 200 mmHg), as well as lower strain and strain rate values.

  3. The Planeterrella experiment: from individual initiative to networking

    Science.gov (United States)

    Lilensten, J.; Provan, G.; Barthelemy, M.; Simon Wedlund, C.; Gronoff, G.; Vanlommel, P.; Brekke, A.; Garnier, P.; Grimald Rochel, S.

    2013-12-01

    Space weather is a relatively new discipline, which is still largely unknown amongst the wider public despite its increasing importance in all of our daily lives. Outreach activities can promote awareness of space weather. In particular the visual beauty and excitement of the aurora make these lights a wonderful inspirational hook to enhance understanding of space weather in a general audience. A century ago, the Norwegian experimental physicist Kristian Birkeland, one of the founding fathers of modern space science, demonstrated with his Terrella experiment the formation of the aurora. Recently, a modernized version of the Terrella has been designed in France. This ';';Planeterrella'' experiment allows the visualization of many phenomena that occur in our space environment. Although the Planeterrella was originally a local project, it has developed to become a very successful international public outreach experiment. We believe that its success is due to mainly two factors (i) the Planeterrella is not patented and the plans are free to any public institute and (ii) the project is widely advertised using national and scientific networks, as well as press releases, books and web sites. Today, nine Planeterrellas are in operation, six more are under construction in five different countries including in the US and several more are being planned. During the last five years, about 55 000 people in Europe have attended live Planeterrella demonstration on the formation of auroral light, the space environment and space weather. Many more have seen the Planeterrella being demonstrated on TV. It is now used for education, outreach, scientific, and artistic purposes. We will describes this process and discuss how the Planeterrella project developed to become an international public outreach phenomenon. We also examine some of the lessons learnt along the way such as patented or not, big or small, automatized or hand-operated, and the cost of the overall project. A star (close

  4. The Planeterrella experiment: from individual initiative to networking

    Directory of Open Access Journals (Sweden)

    Garnier Pierre

    2013-02-01

    Full Text Available Space weather is a relatively new discipline, which is still largely unknown amongst the wider public despite its increasing importance in all of our daily lives. Outreach activities can promote awareness of space weather. In particular the visual beauty and excitement of the aurora make these lights a wonderful inspirational hook to enhance understanding of space weather in a general audience. A century ago, the Norwegian experimental physicist Kristian Birkeland, one of the founding fathers of modern space science, demonstrated with his Terrella experiment the formation of the aurora. Recently, a modernized version of the Terrella has been designed. This “Planeterrella” experiment allows the visualization of many phenomena that occur in our space environment. Although the Planeterrella was originally a local project, it has developed to become a very successful international public outreach experiment. We believe that its success is due to mainly two factors (i the Planeterrella is not patented and the plans are free to any public institute and (ii the project is widely advertised using national and European scientific networks such as COST ES 0803, as well as press releases, books and web sites. Today, seven Planeterrellas are in operation, four more are under construction in four different countries and several more are being planned. During the last five years, about 50 000 people in Europe have attended live Planeterrella demonstration on the formation of auroral light, the space environment and space weather. Many more have seen the Planeterrella being demonstrated on TV. The Planeterrella received the first international prize for outreach activities from the Europlanet Framework 7 program in 2010 and the French Ministry of Science outreach prize “Le goût des sciences” in November 2012. This paper describes the process that led to the construction of the first Planeterrella and discusses how the Planeterrella project developed

  5. Paediatric magnetic resonance enteroclysis under general anaesthesia - initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Sadigh, Sophie; Chopra, Mark; Olsen, Oeystein E.; Watson, Tom A. [Great Ormond Street Hospital NHS Foundation Trust, Department of Paediatric Radiology, London (United Kingdom); Sury, Michael R. [Great Ormond Street Hospital NHS Foundation Trust, Department of Paediatric Anaesthetics, London (United Kingdom); Shah, Neil [Great Ormond Street Hospital NHS Foundation Trust, Department of Paediatric Gastroenterology, London (United Kingdom)

    2017-06-15

    MR enterography is the accepted imaging reference standard for small bowel assessment in inflammatory bowel disease. There is an increasing cohort of children with inflammatory bowel disease presenting at an early age (<5 years) with severe disease. Younger children present a technical challenge for enterography because of the need for sedation/general anaesthesia to allow image optimisation and the need for oral contrast to allow adequate luminal assessment. Through our experiences, MR enteroclysis under general anaesthesia has proven to be a successful imaging technique for the work-up of these patients. In this paper, we present our institutional practice for performing MR enteroclysis under general anaesthesia. (orig.)

  6. Laparoscopic pancreaticoduodenectomy in Brisbane, Australia: an initial experience.

    Science.gov (United States)

    Patel, Bhavik; Leung, Universe; Lee, Jerry; Bryant, Richard; O'Rourke, Nicholas; Cavallucci, David

    2017-10-11

    The role of minimally invasive approach for pancreaticoduodenectomy has not yet been well defined in Australia. We present our early experience with laparoscopic pancreaticoduodenectomy (LPD) from Brisbane, Australia. Retrospective review in a prospectively collected database of patients undergoing LPD between 2006 and 2016 was performed. Patients who underwent a hybrid LPD (HLPD) mobilization approach and resection followed by open reconstruction and totally LPD (TLPD) approach were included in this study. Operative characteristics, perioperative outcomes, pathological and survival data were collected. Twenty-seven patients underwent LPD including 17 HLPD (63%) and 10 TLPD (37%) patients. HLPD patients were mostly converted to open for planned reconstruction or vascular resection. With increasing experience, more TLPDs were performed, including laparoscopic anastomoses. Median operating time was 462 min (504 min for TLPD). Median length of hospital stay was 10 days. Histology showed 21 invasive malignancies, two neuroendocrine tumours, two intraductal papillary mucinous neoplasms and two benign lesions. Median nodal harvest was 22. Margin negative resection was achieved in 84% of patients. Twenty-two percent of patients developed a Grade 3/4 complication, including 19% clinically significant pancreatic fistula. There was one perioperative mortality (4%) due to pancreatic fistula, post-operative haemorrhage and sepsis. LPD is a technically challenging operation with a steep learning curve. The early oncological outcomes appear satisfactory. It remains to be determined whether the minimally invasive approach to pancreaticoduodenectomy offers benefits to patients. © 2017 Royal Australasian College of Surgeons.

  7. Light water reactor fuel response during reactivity initiated accident experiments

    Energy Technology Data Exchange (ETDEWEB)

    MacDonald, P. E.; McCardell, R. K.; Martinson, Z. R.; Seiffert, S. L.

    1979-01-01

    Experimental results from six recent Power Burst Facility (PBF) reactivity initiated accident (RIA) tests are compared with data from previous Special Power Excursion Reactor Test (SPERT), and Japanese Nuclear Safety Research Reactor (NSRR) tests. The RIA fuel behavior experimental program recently started in the PBF is being conducted with coolant conditions typical of hot-startup conditions in a commercial boiling water reactor. The SPERT and NSRR test programs investigated the behavior of single or small clusters of light water reactor (LWR) type fuel rods under approximate room temperature and atmospheric pressure conditions in capsules containing stagnant water. As observed in the SPERT and NSRR tests, energy deposition, and consequent enthalpy increase in the PBF test fuel, appears to be the single most important variable. However, the consequences of failure at boiling water hot-startup system conditions appear to be more severe than previously observed in either the stagnant capsule SPERT or NSRR tests. Metallographic examination of both previously unirradiated and irradiated PBF fuel rod cross sections revealed extensive variation in cladding wall thicknesses (involving considerable plastic flow) and fuel shattering along grain boundaries in both restructured and unrestructured fuel regions. Oxidation of the cladding resulted in fracture at the location of cladding thinning and disintegration of the rods during quench. In addition,swelling of the gaseous and potentially volatile fission products in previously irradiated fuel resulted in volume increases of up to 180% and blockage of the coolant channels within the flow shrouds surrounding the fuel rods.

  8. Robotic-assisted partial Nephrectomy: initial experience in South America

    Directory of Open Access Journals (Sweden)

    Gustavo C. Lemos

    2011-08-01

    Full Text Available OBJECTIVE:To report the initial outcomes of robotic-assisted partial nephrectomy in a tertiary center in South America. MATERIAL AND METHODS: From 11/2008 to 12/2009, a total of 16 transperitoneal robotic-assisted partial nephrectomies were performed in 15 patients to treat 18 kidney tumors. One patient with bilateral tumor had two procedures, while two patients with two synchronous unilateral tumors had a single operation to remove them. Eleven (73% patients were male and the right kidney was affected in 7 (46% patients. The median patient age and tumor size were 57 years old and 30 mm, respectively. Five (28% tumors were hilar and/or centrally located. RESULTS: The median operative time, warm ischemia time and estimated blood loss was 140 min, 27 min and 120 mL, respectively. Blood transfusion was required in one patient with bilateral tumor, and one additional pyelolithotomy was performed due to a 15mm stone located in the renal pelvis. The histopathology analysis showed 15 (83% malignant tumors, which 10 (67% were clear cell carcinoma. The median hospital stay was 72 hrs and no major complication was observed. CONCLUSION: Robotic-assisted partial nephrectomy is safe and represents a valuable option to perform minimally invasive nephron-sparing surgery.

  9. Construction and Initial Validation of the Multiracial Experiences Measure (MEM)

    Science.gov (United States)

    Yoo, Hyung Chol; Jackson, Kelly; Guevarra, Rudy P.; Miller, Matthew J.; Harrington, Blair

    2015-01-01

    This article describes the development and validation of the Multiracial Experiences Measure (MEM): a new measure that assesses uniquely racialized risks and resiliencies experienced by individuals of mixed racial heritage. Across two studies, there was evidence for the validation of the 25-item MEM with 5 subscales including Shifting Expressions, Perceived Racial Ambiguity, Creating Third Space, Multicultural Engagement, and Multiracial Discrimination. The 5-subscale structure of the MEM was supported by a combination of exploratory and confirmatory factor analyses. Evidence of criterion-related validity was partially supported with MEM subscales correlating with measures of racial diversity in one’s social network, color-blind racial attitude, psychological distress, and identity conflict. Evidence of discriminant validity was supported with MEM subscales not correlating with impression management. Implications for future research and suggestions for utilization of the MEM in clinical practice with multiracial adults are discussed. PMID:26460977

  10. Construction and initial validation of the Multiracial Experiences Measure (MEM).

    Science.gov (United States)

    Yoo, Hyung Chol; Jackson, Kelly F; Guevarra, Rudy P; Miller, Matthew J; Harrington, Blair

    2016-03-01

    This article describes the development and validation of the Multiracial Experiences Measure (MEM): a new measure that assesses uniquely racialized risks and resiliencies experienced by individuals of mixed racial heritage. Across 2 studies, there was evidence for the validation of the 25-item MEM with 5 subscales including Shifting Expressions, Perceived Racial Ambiguity, Creating Third Space, Multicultural Engagement, and Multiracial Discrimination. The 5-subscale structure of the MEM was supported by a combination of exploratory and confirmatory factor analyses. Evidence of criterion-related validity was partially supported with MEM subscales correlating with measures of racial diversity in one's social network, color-blind racial attitude, psychological distress, and identity conflict. Evidence of discriminant validity was supported with MEM subscales not correlating with impression management. Implications for future research and suggestions for utilization of the MEM in clinical practice with multiracial adults are discussed. (c) 2016 APA, all rights reserved).

  11. [Initial experience of thoracic surgery in Klaipeda regional Hospital].

    Science.gov (United States)

    Bagajevas, Aleksandras

    2002-01-01

    Study and profound analysis of primary clinical results of the recently established department of Thoracic surgery. Klaipeda Regional Hospital currently functions as a multiprofile facility and covers Western area of Lithuania. More than 274 patients were cured here within the past 8 months. Majority of patients, i.e. 205 (74.82%) were operated; 26 (12.68%) of them underwent surgery urgently and 179 (87.32%) - on planned basis. A large scale of different interventions was performed: 156 (76.1%) - complex operations of lungs, pleura, esophagus, mediastinum and others. All the rest - 49 (23.9%) - operations with minimally invasive procedures, i.e. thoracoscopy, mediastinoscopy, tracheostomy, esophagus stenting etc. Primary experience of thoracic surgery in Klaipeda regional hospital has good basis for the future development of this activity.

  12. Breast cancer screening with tomosynthesis--initial experiences.

    Science.gov (United States)

    Tingberg, A; Förnvik, D; Mattsson, S; Svahn, T; Timberg, P; Zackrisson, S

    2011-09-01

    Experiences gained so far using tomosynthesis for breast cancer screening will be reported. A short summary of results from preparatory studies will also be presented. The sensitivity and specificity of breast tomosynthesis (BT) will be compared with conventional two-dimensional digital mammography (DM) for breast cancer screening in a population-based study. Over 2000 women have been examined so far with BT and DM. The BT reading is significantly more time-consuming than the DM reading. Preparatory studies have shown that BT has a higher diagnostic precision and higher accuracy of size measurements and stage determination than DM. There is potential to use lower compression force with BT compared with DM, without decreasing the diagnostic accuracy. BT might play an important role in clinical as well as screening mammography. A large-scale population-based study to investigate BT as a screening modality is underway.

  13. Weekly variability in outcome expectations: Examining associations with related physical activity experiences during physical activity initiation

    NARCIS (Netherlands)

    Loehr, V.G.; Baldwin, A.S.; Rosenfield, D.; Smits, J.A.J.

    2014-01-01

    Little is known about how outcome expectations change after physical activity initiation and whether changes are associated with physical activity experiences. In a diary study, physically inactive adults (N = 102) initiated an exercise regimen and reported their experiences daily (e.g. progress

  14. Challenge in Numerical Software for Microcomputers

    Energy Technology Data Exchange (ETDEWEB)

    Cody, W J

    1977-09-02

    Microcomputers are now capable of serious numerical computation using programmed floating-point arithmetic and Basic compilers. Unless numerical software designers for these machines exploit experience gained in providing software for larger machines, history will repeat with the initial spread of treacherous software. This paper discusses good software, especially for the elementary functions, in terms of reliability and robustness. The emphasis. is on insight rather than detailed algorithms, to show why certain things are important and how they may be achieved.

  15. Training in radiological protection for interventional cardiologists. Initial European experience

    Energy Technology Data Exchange (ETDEWEB)

    Vano, E.; Back, C.; Beissel, J.; Bernardi, G.; Padovani, G.

    2004-07-01

    One of the first European experiences to train interventional cardiologists (IC) in radiological protection (RP) to fulfil the requirements of the Medical Exposures Directive is described. A pilot course was taught by an international panel of lecturers at the National Institute of Cardiac Surgery and Interventional Cardiology in Luxembourg following the educational objectives recommended by the European Guidelines RP-116. Senior cardiologists attended the course of two full days (16 hours of training). Practical sessions with the X ray systems installed in the Institute hosting the course were also included. Twenty people attended the course (IC, medical physicists and radiographers). The nine IC who follow regularly the course and had attended the exam, had passed it. A survey was carried out at the end of the training in order to improve the programme. The main results were the following: The course length (short/suitable/long) was considered suitable by 60% of delegates. A 40% believed the course long. The mean course score (maximum of 10 points) was 8.3. The mean lecturer score (maximum of 10 points) was 8.0. The subjects related with biological effects and optimization should have further emphasis in future versions of the course. (Author)

  16. Application of robotics in general surgery: initial experience.

    Science.gov (United States)

    Nguyen, Ninh T; Hinojosa, Marcelo W; Finley, David; Stevens, Melinda; Paya, Mahbod

    2004-10-01

    Robotic surgery was recently approved for clinical use in general abdominal surgery. The aim of this study was to review our experience with the da Vinci surgical system during laparoscopic general surgical procedures. Eighteen patients underwent robotically assisted laparoscopic abdominal surgery between June 2002 and March 2003. Main outcome measures were operative time, room setup time, robotic arm-positioning and surgical time, blood loss, conversion to laparoscopy, length of stay, and morbidity. The types of robotically assisted laparoscopic procedures were excision of gastric leiomyoma (n = 1), Heller myotomy (n = 1), cholecystectomy (n = 2), gastric banding (n = 2), Nissen fundoplication (n = 4), and gastric bypass (n = 8). The mean room setup time was 63 +/- 14 minutes, and the mean robotic arm-positioning time was 16 +/- 7 minutes. Conversion to laparoscopy occurred in two (11%) of 18 cases because of equipment difficulty (n = 1) and technical difficulty (n = 1). Estimated blood loss was 91 +/- 71 mL. The mean operative time was 156 +/- 42 minutes, and the robotic operative time was 27% of the total operative time. The mean length of hospital stay was 2.2 +/- 1.5 days. There was one postoperative wound infection and one anastomotic stricture. Robotically assisted laparoscopic abdominal surgery is feasible and safe; however, the theoretical advantages of the da Vinci surgical system were not clinically apparent.

  17. Initial clinical experience using a novel laparoscopy assistant.

    Science.gov (United States)

    Mishra, Raineesh; Martínez, Arturo Minor; Lorias Espinoza, Daniel

    2011-05-01

    This article presents the first clinical and experimental experiences of the PMASS (Postural Mechatronic Assistance Solo Surgery) from a prospective study carried on on thirteen laparoscopic procedures. Also, their advantages and disadvantages are identified. The PMASS is a system with three articulations; two articulations are passive and one is active; this handles the optic in real time, reducing the latency time by spatial relocation. The surgeons assisted themselves visually in 13 surgical procedures, having direct and intuitive control in real time of the laparoscopic vision field using the PMASS. The surgical and delay time was documented for each surgery. The surgical procedures were: Laparoscopic appendicectomy, ovarian cystectomy and laparoscopic sterilization. In all procedures, surgeons were able to auto-navigate in real time and there was no visual tremor while using the system. The global average times taken to perform the self-assisted surgery with the PMASS for the laparoscopic appendicectomies were 45 ± 4.5 minutes, ovarian cystectomies 49 ± 3.5 minutes and for the laparoscopic sterilization 22 ± 2 minutes. The approximate set-up time of PMASS was one minute, and removal almost a minute (the time required by the surgeon to remove the harness after completing the surgery). The laparoscope itself disengages from the PMASS in a couple of seconds approximately. There were no transoperative or postoperative complications during the procedures. Thirteen laparoscopic procedures were performed, the design of the mechatronic assistance allowed the surgeon to self-assist visually in real time and in an autonomous way in the solo-surgery mode, without compromising the surgical performance and the morbidity. Additionally, the latency times are also reduced by space relocation and coupling of the telescope.

  18. Initial Experience of Percutaneous Nephrolithotomy at Lumbini Medical College

    Directory of Open Access Journals (Sweden)

    Prakash Sapkota

    2013-06-01

    Full Text Available   Introduction: Renal stone disease is a challenging problem in urologic practice especially in our locality because of large stone burden and recurrence. Since ,the early 1980s when percutaneous nephrolithotomy (PCNL was established for management of renal stones, open surgical procedures have virtually been replaced. PCNL is a safe, effective and minimally invasive approach compared to open surgery for patients with large single, multiple or staghorn stones. The aim of this prospective study was to evaluate and to review our experience with PCNL in management of renal and upper ureteric stones.   Methods: Prospective study carried out at Lumbini Medical College and Teaching Hospital during 1stJanuary 2011 to 31st October 2011. Sixty patients were evaluated and subjected to PCNL. After clinical investigations like ultrasonography (USG and intravenous urography (IVU, once patients were found to have renal or upper ureteric stones they were informed and explained about PCNL, its likely complications, probable hospital stay, the cost of treatment and data were recorded along with the operative time, estimated blood loss, stone burden, stone-free rate, length of hospitalization and complications .Patients were followed up after three months to rule out recurrence of stones by plain abdominal x-ray of kidney, ureter and bladder and USG.   Results: Out of 60 patients 35 were male and 25 were female (M: F=1.4:1 with mean age of 37 years and were subjected to PCNL monotherapy. With the average stone size of 3.26cm, the mean operative time was 78 minutes. Complete stone removal achieved by PCNL alone in 60 cases, with insignificant residual small stones we achieved 97% stone clearance rate. The mean hospital stay was 3.7 days. No Serious complications were encountered, 9 (15% patients required blood transfusion and 3 (5% patients developed transient post-operative pyrexia.   Conclusion: PCNL is the first line treatment option for management of large

  19. Digital breast tomosynthesis (DBT): initial experience in a clinical setting

    Energy Technology Data Exchange (ETDEWEB)

    Skaane, Per; Gullien, Randi; Eben, Ellen B.; Haakenaasen, Unni; Naess Jebsen, Ingvild; Krager, Mona [Dept of Radiology, Oslo Univ. Hospital Ullevaal, Univ. of Oslo, Oslo (Norway)], e-mail: PERSKA@ous-hf.no; Bjoerndal, Hilde [Dept of Radiology, Oslo Univ. Hospital The Norwegian Radium Hospital, Oslo (Norway); Ekseth, Ulrika [Curato Roentgen Institute, Oslo (Norway); Jahr, Gunnar [Dept. of Radiology, Oslo Univ. Hospital Rikshospitalet, Oslo (Norway)

    2012-06-15

    false-positive findings. The side-by-side feature analysis showed higher conspicuity scores for tomosynthesis compared to conventional 2D for cancers presenting as spiculated masses and distortions. Conclusion: Tomosynthesis is a promising new technique. Our preliminary clinical experience shows that there is a potential for increasing the sensitivity using this new technique, especially for cancers manifesting as spiculated masses and distortions.

  20. nanoHUB.org: Experiences and Challenges in Software Sustainability for a Large Scientific Community

    Directory of Open Access Journals (Sweden)

    Lynn Zentner

    2014-07-01

    Full Text Available The science gateway nanoHUB.org, funded by the National Science Foundation (NSF, serves a large scientific community dedicated to research and education in nanotechnology with community-contributed simulation codes as well as a vast repository of other materials such as recorded presentations, teaching materials, and workshops and courses. Nearly 330,000 users annually access over 4400 items of content on nanoHUB, including 343 simulation tools. Arguably the largest nanotechnology facility in the world, nanoHUB has led the way not only in providing open access to scientific code in the nanotechnology community, but also in lowering barriers to the use of that code, by providing a platform where developers are able to easily and quickly deploy code written in a variety of languages with user-friendly graphical user interfaces and where users can run the latest versions of codes transparently on the grid or other powerful resources without ever having to download or update code. Being a leader in open access code deployment provides nanoHUB with opportunities and challenges as it meets the current and future needs of its community. This paper discusses the experiences of nanoHUB in addressing and adapting to the changing landscape of scientific software in ways that best serve its community and meet the needs of the largest portion of its user base.

  1. Design of the Jet Performance Software for the ATLAS Experiment at LHC

    CERN Document Server

    Doglioni, C; The ATLAS collaboration; Loch, P; Perez, K; Vitillo, RA

    2011-01-01

    This paper describes the design and implementation of the JetFramework, a software tool developed for the data analysis of the ATLAS experi- ment at CERN. JetFramework is based on Athena, an object oriented framework for data processing. The JetFramework Athena package im- plements a configurable data-flow graph (DFG) to represent an analysis. Each node of the graph can perform some computation on one or more particle collections in input. A standard set of nodes to retrieve, filter, sort and plot collections are provided. Users can also implement their own computation units inheriting from a generic interface. The analysis graph can be declared and configured in an Athena options file. To provide the requested flexibility to configure nodes from a configuration file, a sim- ple expression language permits to specify selection and plotting criterias. Viewing an analysis as an explicit DFG permits end-users to avoid writing code for repetitive tasks and to reuse user-defined computation units in other analysis...

  2. Negative Interest Rates: Central Banks Initiated an Experiment

    Directory of Open Access Journals (Sweden)

    Aleksey N. Burenin

    2016-01-01

    Full Text Available Negative interest rates appeared as a consequence of economic problems that countries with market economy came across after the crises of2007-2008. The attempts of monetary authorities to stimulate economies with the help of quantitative easing didn't bring the desired result. That's why the central banks once again resorted to a traditional tool of their monetary policy of changing interest rates. But this time they launched an experiment, they used negative interest rates. The European Central Bank, the Swedish Riksbank, the Bank of Japan, and the National Bank of Hungary introduced negative rates in order to stimulate economic growth and fight the threat of deflation, the Danish National Bank and the Swiss National Bank tried to deter appreciation of their currencies. Negative rates of the central banks brought about negative yields of government and nongovernment securities in several countries. The problem acquires an aggravated form due to the fact that negative rates appeared in several European countries simultaneously at the moment when global financial markets were not in crises. Some questions arise concerning the negative rates, for example, how low can central banks bring down the rates in the future, what is their influence on the stock markets, what is the reaction of depositors to the introduction of negative deposit rates by commercial banks, must one consider a negative rate as a rate of interest or payment to store money of the depositor, in which circumstances negative rates can be justified to fight deflation. The last question plays an important role, because recent studies find that positive economic growth is possible during deflation. If central banks don't take this nuance into consideration, they can create economic imbalances by increasing liquidity. Negative rates are not as inoffensive as it may seem at first glance. Not far ago an investor, who tried to averse risk, was buying government securities. Their yields

  3. Experiences in Teaching a Graduate Course on Model-Driven Software Development

    Science.gov (United States)

    Tekinerdogan, Bedir

    2011-01-01

    Model-driven software development (MDSD) aims to support the development and evolution of software intensive systems using the basic concepts of model, metamodel, and model transformation. In parallel with the ongoing academic research, MDSD is more and more applied in industrial practices. After being accepted both by a broad community of…

  4. Generation of Source Data for Experiments with Network Attack Detection Software

    Science.gov (United States)

    Kotenko, Igor; Chechulin, Andrey; Branitskiy, Alexander

    2017-03-01

    The paper suggests a new approach for traffic generation and the architecture of the software tool for evaluation of attack detection and response mechanisms. To assess the proposed approach the automatic network attack detection and response mechanism Threshold Random Walk (TRW) was chosen and implemented. The results of evaluation of this mechanism by the proposed software tool are presented.

  5. DYNAMIC MATHEMATICAL SOFTWARE IN THE CONTEXT OF THE MODERN TEACHER’S WORK: THE RESULTS OF THE PEDAGOGICAL EXPERIMENT

    Directory of Open Access Journals (Sweden)

    O. Semenikhina

    2015-02-01

    Full Text Available The article presents the results of pedagogical research about the willingness and the psychological readiness to use dynamic mathematical software (DMS by working and future math teachers. The experiment was conducted during 2010-2014 at the Sumy Makarenko State Pedagogical University. The results of the research demonstrate the dynamics of the increase in the number of teachers and students who wish to use DMS in their future careers. It was used nonparametric method for dependent samples - the McNemar’s test - to handle the results of the research. The hypothesis, that the study of the Special course of the use of dynamic mathematical software by future math teachers has a positive impact on the willingness and the readiness to use such software in their own professional activities, was confirmed at the significance level of 0.05. Additionally, the results of the experiment on the willingness and the readiness to support the teaching of some subjects (algebra, planimetry, solid geometry and analysis by dynamic mathematical software, and the willingness to use some dynamic mathematical software (Gran (Gran1, Gran2d, Gran3d, GeoGebra, Сabri, MathKit, DG, GS by Ukrainian math teachers were given. Analysis of results revealed that working and future math teachers prefer to work with Gran and GeoGebra, respectively. That is why the further work on the creation of educational materials on the use of GeoGebra is useful.

  6. Augmented Reality Guidance for the Resection of Missing Colorectal Liver Metastases: An Initial Experience.

    Science.gov (United States)

    Ntourakis, Dimitrios; Memeo, Ricardo; Soler, Luc; Marescaux, Jacques; Mutter, Didier; Pessaux, Patrick

    2016-02-01

    Modern chemotherapy achieves the shrinking of colorectal cancer liver metastases (CRLM) to such extent that they may disappear from radiological imaging. Disappearing CRLM rarely represents a complete pathological remission and have an important risk of recurrence. Augmented reality (AR) consists in the fusion of real-time patient images with a computer-generated 3D virtual patient model created from pre-operative medical imaging. The aim of this prospective pilot study is to investigate the potential of AR navigation as a tool to help locate and surgically resect missing CRLM. A 3D virtual anatomical model was created from thoracoabdominal CT-scans using customary software (VR RENDER(®), IRCAD). The virtual model was superimposed to the operative field using an Exoscope (VITOM(®), Karl Storz, Tüttlingen, Germany). Virtual and real images were manually registered in real-time using a video mixer, based on external anatomical landmarks with an estimated accuracy of 5 mm. This modality was tested in three patients, with four missing CRLM that had sizes from 12 to 24 mm, undergoing laparotomy after receiving pre-operative oxaliplatin-based chemotherapy. AR display and fine registration was performed within 6 min. AR helped detect all four missing CRLM, and guided their resection. In all cases the planned security margin of 1 cm was clear and resections were confirmed to be R0 by pathology. There was no postoperative major morbidity or mortality. No local recurrence occurred in the follow-up period of 6-22 months. This initial experience suggests that AR may be a helpful navigation tool for the resection of missing CRLM.

  7. Tracer: A general-purpose software library for logging events in computerized experiments

    National Research Council Canada - National Science Library

    Lahl, Olaf; Pietrowsky, Reinhard

    2008-01-01

    .... The Tracer software library presented here is a lightweight Windows programming interface that provides experimenters the ability to trace events and status notifications on one or more remote computers and log files...

  8. On the Role of Formal Methods in Software Certification: An Experience Report

    Science.gov (United States)

    2009-01-01

    software, formal verification , formal specification, certification 1 Introduction Prior to its deployment, a security-critical software system may undergo a...the assumptions for ED make explicit those routines that the certification authority agreed were outside the scope of the formal verification . C.L...IEEE Computer 25 (1992), pp. 40–51. [14] Owre, S., J. Rushby, N. Shankar and F. von Henke, Formal verification for fault-tolerant architectures

  9. Software Productivity of Field Experiments Using the Mobile Agents Open Architecture with Workflow Interoperability

    Science.gov (United States)

    Clancey, William J.; Lowry, Michael R.; Nado, Robert Allen; Sierhuis, Maarten

    2011-01-01

    We analyzed a series of ten systematically developed surface exploration systems that integrated a variety of hardware and software components. Design, development, and testing data suggest that incremental buildup of an exploration system for long-duration capabilities is facilitated by an open architecture with appropriate-level APIs, specifically designed to facilitate integration of new components. This improves software productivity by reducing changes required for reconfiguring an existing system.

  10. Build Less Code, Deliver More Science: An Experience Report on Composing Scientific Environments using Component-based and Commodity Software Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Gorton, Ian [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Computational Sciences and Math Division; Liu, Yan [Concordia University Montreal, Quebec, (Canada).; Lansing, Carina S. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Computational Sciences and Math Division; Elsethagen, Todd O. [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Computational Sciences and Math Division; Kleese van Dam, Kerstin [Pacific Northwest National Lab. (PNNL), Richland, WA (United States). Computational Sciences and Math Division

    2013-07-17

    Modern scientific software is daunting in its diversity and complexity. From massively parallel simulations running on the world’s largest supercomputers, to visualizations and user support environments that manage ever growing complex data collections, the challenges for software engineers are plentiful. While high performance simulators are necessarily specialized codes to maximize performance on specific supercomputer architectures, we argue the vast majority of supporting infrastructure, data management and analysis tools can leverage commodity open source and component-based technologies. This approach can significantly drive down the effort and costs of building complex, collaborative scientific user environments, as well as increase their reliability and extensibility. In this paper we describe our experiences in creating an initial user environment for scientists involved in modeling the detailed effects of climate change on the environment of selected geographical regions. Our approach composes the user environment using the Velo scientific knowledge management platform and the MeDICi Integration Framework for scientific workflows. These established platforms leverage component-based technologies and extend commodity open source platforms with abstractions and capabilities that make them amenable for broad use in science. Using this approach we were able to deliver an operational user environment capable of running thousands of simulations in a 7 month period, and achieve significant software reuse.

  11. [Mandibular reconstruction with fibula free flap. Experience of virtual reconstruction using Osirix®, a free and open source software for medical imagery].

    Science.gov (United States)

    Albert, S; Cristofari, J-P; Cox, A; Bensimon, J-L; Guedon, C; Barry, B

    2011-12-01

    The techniques of free tissue transfers are mainly used for mandibular reconstruction by specialized surgical teams. This type of reconstruction is mostly realized in matters of head and neck cancers affecting mandibular bone and requiring a wide surgical resection and interruption of the mandible. To decrease the duration of the operation, surgical procedure involves generally two teams, one devoted to cancer resection and the other one to raise the fibular flap and making the reconstruction. For a better preparation of this surgical procedure, we propose here the use of a medical imaging software enabling mandibular reconstructions in three dimensions using the CT-scan done during the initial disease-staging checkup. The software used is Osirix®, developed since 2004 by a team of radiologists from Geneva and UCLA, working on Apple® computers and downloadable free of charge in its basic version. We report here our experience of this software in 17 patients, with a preoperative modelling in three dimensions of the mandible, of the segment of mandible to be removed. It also forecasts the numbers of fragments of fibula needed and the location of osteotomies. Copyright © 2009 Elsevier Masson SAS. All rights reserved.

  12. Analysis and proposal of the new architecture of the selected parts of the software support of the COMPASS experiment

    CERN Document Server

    Jary, Vladimir

    This work focuses on the data acquisition system of the Compass experiment at CERN. At first the database current subsystem that suffered from increased load during year 2009 is analysed. The reasons of problems are identified and new architecture that includes replication, backups, and monitoring for achieving the high availability and reliability is proposed and implemented. Several advanced database features including partitioned tables or storage engines are described and tested. Then, the process of implementation of the remote control and monitoring of the experiment is explained. As the existing data acquisition system is partly based on a deprecated technologies, development of a new architecture has started. We focus on requirements analysis and proposal of a control and monitoring software for the new hardware platform based on the FPGA technology. The software is to be deployed in a heterogenous network environment. According to the proposal, the system is built on the DIM communication library. Ro...

  13. Comparing overflow and wave-overtopping induced breach initiation mechanisms in an embankment breach experiment

    OpenAIRE

    van Damme Myron; Ponsioen Luc; Herrero Monica; Peeters Patrik

    2016-01-01

    As part of the SAFElevee project Delft University of Technology collabored with Flanders Hydraulics Research, and Infram B.V. in the preperation and execution of a full scale embankment breach experiment in November 2015. This breach experiment was performed on an 3.5m high embankment with a sand core and clay outer layer situated along the tidal river Scheldt in Belgium near Schellebelle. During the experiment a wave overtopping simulator and overflow simulator were used to initiate a breach...

  14. A qualitative case study of LifeGuide: users' experiences of software for developing Internet-based behaviour change interventions.

    Science.gov (United States)

    Williams, Sarah; Yardley, Lucy; Wills, Gary B

    2013-03-01

    Previously, behavioural scientists seeking to create Internet-based behaviour change interventions have had to rely on computer scientists to actually develop and modify web interventions. The LifeGuide software was designed to enable behavioural researchers to develop and adapt Internet-based behavioural interventions themselves. This article reports a qualitative case study of users' experiences and perceptions of the LifeGuide software. The aim was to explore users' experiences and their perceptions of the benefits and limitations of this approach to intervention development. Twenty LifeGuide users took part in semi-structured interviews and one provided feedback via email. Thematic analysis identified three overarching themes: 'Recognising LifeGuide's potential', 'I'm not a programmer' and 'Knowledge sharing - the future of LifeGuide'. Users valued LifeGuide's potential to allow them to flexibly develop and modify interventions at little cost. However, users noted that their lack of programming experience meant that they needed to learn new skills for using the software, and they varied in the extent to which they felt able to develop interventions without any input from programmers. Respondents saw the potential of using the LifeGuide Community Website to share technical support and examples of intervention components to support their use of LifeGuide.

  15. On the Understandability of Semantic Constraints for Behavioral Software Architecture Compliance: A Controlled Experiment

    OpenAIRE

    Christoph Czepa; Huy Tran; Uwe Zdun; Thanh Tran; Erhard Weiss; Christoph Ruhsam

    2017-01-01

    Software architecture compliance is concerned with the alignment of implementation with its desired architecture and detecting potential inconsistencies. The work presented in this paper is specifically concerned with behavioral architecture compliance. That is, the focus is on semantic alignment of implementation and architecture. In particular, this paper evaluates three representative approaches for describing semantic constraints in terms of their understandability, namely natural languag...

  16. Engagement and Learning through Social Software in Finance: A Retrospective on the "Trading Room" Experience

    Science.gov (United States)

    Jain, Ameeta; Thomson, Dianne; Farley, Alan; Mulready, Pamela

    2012-01-01

    The introduction of a social software blog space called the Trading Room in an undergraduate finance unit generated a great deal of activity to support student learning. A subsequent evaluation of this innovation, viewed through the lens of Activity Theory, demonstrated that students perceived high value in the opportunity it provided for them to…

  17. Use of Student Experiments for Teaching Embedded Software Development Including HW/SW Co-Design

    Science.gov (United States)

    Mitsui, H.; Kambe, H.; Koizumi, H.

    2009-01-01

    Embedded systems have been applied widely, not only to consumer products and industrial machines, but also to new applications such as ubiquitous or sensor networking. The increasing role of software (SW) in embedded system development has caused a great demand for embedded SW engineers, and university education for embedded SW engineering has…

  18. The Relationship between Gender and Students' Attitude and Experience of Using a Mathematical Software Program (MATLAB)

    Science.gov (United States)

    Ocak, Mehmet A.

    2006-01-01

    This correlation study examined the relationship between gender and the students' attitude and prior knowledge of using one of the mathematical software programs (MATLAB). Participants were selected from one community college, one state university and one private college. Students were volunteers from three Calculus I classrooms (one class from…

  19. Teaching and Learning about Functions at Upper Secondary Level: Designing and Experimenting the Software Environment Casyopee

    Science.gov (United States)

    Lagrange, Jean-Baptiste

    2010-01-01

    Casyopee is an evolving project focusing on the development of both software and classroom situations to teach algebra and analysis at upper secondary level. In this article, we sketch the rationales for the Casyopee project in relationship with the focus on functions in upper secondary curricula. To evaluate Casyopee's contribution, we present…

  20. The Data Aggregation Project: Free Software that Transforms the Student Laboratory Experience.

    Science.gov (United States)

    Brewer, Steven D.; Hoogendky, Tom; Hoagland, Donald B.

    2003-01-01

    Found that in an introductory biology course at the University of Massachusetts Amherst, adoption of the Data Aggregation Project (free software that allows students in a course to aggregate a large body of data for some particular problem) resulted in an increase in the number of data points students analyzed per semester by a factor of almost…

  1. User-Driven Quality Certification of Workplace Software, the UsersAward Experience

    National Research Council Canada - National Science Library

    Walldius, Ake; Sundblad, Yngve; Bengtsson, Lars; Lind, Torbjorn; Sandblad, Bengt

    2004-01-01

    ... with trade unions in 1999-2002. The ITQ project is part of a network, UsersAward, which continues to work for the goal to develop and maintain a strategy for good software products on the work floor through strong user influence...

  2. Dizziness and the genetic influences on subjective experiences to initial cigarette use.

    Science.gov (United States)

    Haberstick, Brett C; Ehringer, Marissa A; Lessem, Jeffrey M; Hopfer, Christian J; Hewitt, John K

    2011-02-01

    To examine individual differences in positive and negative subjective experiences to initial cigarette use. Retrospective self-reports of initial subjective experiences were examined to estimate the genetic and environmental influences and the extent of their covariation across different effects. Data was drawn from 2482 young adult same-and opposite sex twins- and siblings participating in the National Longitudinal Study of Adolescent Health. Subjective experiences were retrospectively collected using the Early Smoking Experience (ESE) questionnaire. Positive experiences evidenced moderate heritable contributions (40%, 95% CI: 0.22 to 0.56), as did an overall hedonic measure (34%, 95% CI: 0.22 to 0.46) and dizziness (34%, 95% CI: 0.15 to 0.52). Negative experiences evidenced small heritable contributions (13%, 95% CI: 0.00 to 0.36). Individual specific environmental influences were strong and accounted for the remaining proportion of observed variation in these experiences. Multivariate genetic modeling identified a moderately heritable underlying factor (37%, 95% CI: 0.22 to 0.52) that influenced the covariation of diverse subjective experiences and loaded most heavily on dizziness. Positive experiences also evidence residual genetic influences that were uncorrelated with other subjective experiences. How a person experiences their initial few cigarettes is due to both heritable contributions and environmental experiences unique to the person. The covariation of diverse subjective experiences appears to be due to a heritable latent sensitivity to the chemicals contained in an average cigarette and is best indexed by dizziness. © 2010 The Authors, Addiction © 2010 Society for the Study of Addiction.

  3. A Hardware and Software Perspective of the Fifth Materials on the International Space Station Experiment (MISSE-5)

    Science.gov (United States)

    Krasowski, Michael; Greer, Lawrence; Flatico, Joseph; Jenkins, Phillip; Spina, Dan

    2005-01-01

    Conducting space experiments with small budgets is a fact of life for many design groups with low-visibility science programs. One major consequence is that specialized space grade electronic components are often too costly to incorporate into the design. Radiation mitigation now becomes more complex as a result of being restricted to the use of commercial off-the-shelf (COTS) parts. Unique hardware and software design techniques are required to succeed in producing a viable instrument suited for use in space. This paper highlights some of the design challenges and associated solutions encountered in the production of a highly capable, low cost space experiment package.

  4. Quality assessment with the AGIR software results and experience; Qualitaetsmanagement mittels AGIR: Ergebnisse und Erfahrungen

    Energy Technology Data Exchange (ETDEWEB)

    Rauch, D.; Kotter, E.; Kurtz, C.; Schaefer, O.; Ehritt-Braun, C.; Burger, D.; Schaper, J.; Uhrmeister, P. [Freiburg Univ. (Germany). Radiologische Universitaetsklinik, Abt. fuer Roentgendiagnostik

    2001-02-01

    Purpose: To evaluate whether a new software from the working group for interventional radiology (AGIR) is an appropriate tool for quality assurance in interventional radiology, and presentation of results acquired within the quality improvement process in 1999. Patients and methods: AGIR-defined parameters such as patient data, risk profile, given interventions as well as complications were registered by a recently developed software. Based on monthly data analyses, possible complications were identified and discussed in morbidity and mortality conferences. Results: 1014 interventions were performed in our institution in 1999. According to criteria established by AGIR, the complication rate was 2.7%. In addition and according to SCVIR criteria, complications were distinguished quantitatively in five classes and semiquantitatively in minor and major groups. The result was a minor complication rate of 1.8%, and a major rate of 0.9%. There were no cases of death associated with the intervention. Further strategies were developed in order to reduce the complication rate. Conclusion: Extensive quality assurance methods can be integrated in daily routine work. These methods lead to an intensive transparency of treatment results, and allow the implementation of continuous quality improvements. The development of the software is a first step in establishing a nation-wide quality assurance system. Nevertheless, modification and additional definition of the AGIR predefined parameters are required, for example, to avoid unnecessary procedures. (orig.) [German] Ziel: Evaluierung einer neuen Software der arbeitsgemeinschaft interventionelle radiologie (AGIR) hinsichtlich der Eignung als Instrument zur Qualitaetssicherung in der interventionellen Radiologie sowie Praesentation der Ergebnisse innerhalb des Qualitaetsprozesses aus dem Jahre 1999. Patienten und Methoden: Mit Hilfe einer neuen Software wurden AGIR definierte Parameter wie Patientendaten, Risikoprofil, die jeweilige

  5. Eating at worksites in Nordic countries: national experiences and policy initiatives

    DEFF Research Database (Denmark)

    Jørgensen, Michael Søgaard; Arsky, Gunn Helene; Brandhøj, Mia

    2010-01-01

    of dietary habits of the employees and some experiments with healthier worksite eating schemes. Blue-collar employees, employees with working hours outside normal working hours and employees with shifting worksites are likely to be offered less organised and less healthy food schemes. Worksites experiments...... with healthier worksite eating schemes based on employee participation can change the worksite eating substantially, also at blue-collar worksites. However, the dissemination to other worksites not participating in experiments seems limited. There is need for more research in the embedding of experiments......Purpose - The article aims at reviewing national experiences and policy initiatives within worksite eating in four Nordic countries in order to compare the experiences and identify important lessons and needs for future research, experiments and governmental regulation. Design...

  6. Systematic profiling to monitor and specify the software refactoring process of the LHCb experiment

    CERN Document Server

    Couturier, Ben; Lohn, Stefan B

    2014-01-01

    The LHCb upgrade program implies a significant increase in data processing that will not be matched by additional computing resources. Furthermore, new architectures such as many-core platforms can currently not be fully exploited due to memory and I/O bandwidth limitations. A considerable refactoring effort will therefore be needed to vectorize and parallelize the LHCb software, to minimize hotspots and to reduce the impact of bottlenecks. It is crucial to guide refactoring with a profiling system that gives hints to regions in source-code for possible and necessary re-engineering and which kind of optimization could lead to final success. Software optimization is a sophisticated process where all parts, compiler, operating system, external libraries and chosen hardware play a role. Intended improvements can have different effects on different platforms. To obtain precise information of the general performance, to make profiles comparable, reproducible and to verify the progress of performance in the framewo...

  7. Madagascar: open-source software project for multidimensional data analysis and reproducible computational experiments

    Directory of Open Access Journals (Sweden)

    Sergey Fomel

    2013-11-01

    Full Text Available The Madagascar software package is designed for analysis of large-scale multidimensional data, such as those occurring in exploration geophysics. Madagascar provides a framework for reproducible research. By “reproducible research” we refer to the discipline of attaching software codes and data to computational results reported in publications. The package contains a collection of (a computational modules, (b data-processing scripts, and (c research papers. Madagascar is distributed on SourceForge under a GPL v2 license https://sourceforge.net/projects/rsf/. By October 2013, more than 70 people from different organizations around the world have contributed to the project, with increasing year-to-year activity. The Madagascar website is http://www.ahay.org/.

  8. Managing Change in Software Process Improvement

    DEFF Research Database (Denmark)

    Mathiassen, Lars; Ngwenyama, Ojelanki K.; Aaen, Ivan

    2005-01-01

    When software managers initiate SPI, most are ill prepared for the scale and complexity of the organizational change involved. Although they typically know how to deal with large software projects, few managers have sufficient experience with projects that transform organizations. To succeed...... with SPI, software managers must understand the context, know the organizational elements that are involved, and master the tactics that facilitate successful change....

  9. Software engineering

    CERN Document Server

    Sommerville, Ian

    2016-01-01

    For courses in computer science and software engineering The Fundamental Practice of Software Engineering Software Engineering introduces readers to the overwhelmingly important subject of software programming and development. In the past few years, computer systems have come to dominate not just our technological growth, but the foundations of our world's major industries. This text seeks to lay out the fundamental concepts of this huge and continually growing subject area in a clear and comprehensive manner. The Tenth Edition contains new information that highlights various technological updates of recent years, providing readers with highly relevant and current information. Sommerville's experience in system dependability and systems engineering guides the text through a traditional plan-based approach that incorporates some novel agile methods. The text strives to teach the innovators of tomorrow how to create software that will make our world a better, safer, and more advanced place to live.

  10. Negotiation and Decision Making with Collaborative Software: How MarineMap `Changed the Game' in California's Marine Life Protected Act Initiative

    Science.gov (United States)

    Cravens, Amanda E.

    2016-02-01

    Environmental managers and planners have become increasingly enthusiastic about the potential of decision support tools (DSTs) to improve environmental decision-making processes as information technology transforms many aspects of daily life. Discussions about DSTs, however, rarely recognize the range of ways software can influence users' negotiation, problem-solving, or decision-making strategies and incentives, in part because there are few empirical studies of completed processes that used technology. This mixed-methods study—which draws on data from approximately 60 semi-structured interviews and an online survey—examines how one geospatial DST influenced participants' experiences during a multi-year marine planning process in California. Results suggest that DSTs can facilitate communication by creating a common language, help users understand the geography and scientific criteria in play during the process, aid stakeholders in identifying shared or diverging interests, and facilitate joint problem solving. The same design features that enabled the tool to aid in decision making, however, also presented surprising challenges in certain circumstances by, for example, making it difficult for participants to discuss information that was not spatially represented on the map-based interface. The study also highlights the importance of the social context in which software is developed and implemented, suggesting that the relationship between the software development team and other participants may be as important as technical software design in shaping how DSTs add value. The paper concludes with considerations to inform the future use of DSTs in environmental decision-making processes.

  11. Negotiation and Decision Making with Collaborative Software: How MarineMap 'Changed the Game' in California's Marine Life Protected Act Initiative.

    Science.gov (United States)

    Cravens, Amanda E

    2016-02-01

    Environmental managers and planners have become increasingly enthusiastic about the potential of decision support tools (DSTs) to improve environmental decision-making processes as information technology transforms many aspects of daily life. Discussions about DSTs, however, rarely recognize the range of ways software can influence users' negotiation, problem-solving, or decision-making strategies and incentives, in part because there are few empirical studies of completed processes that used technology. This mixed-methods study-which draws on data from approximately 60 semi-structured interviews and an online survey--examines how one geospatial DST influenced participants' experiences during a multi-year marine planning process in California. Results suggest that DSTs can facilitate communication by creating a common language, help users understand the geography and scientific criteria in play during the process, aid stakeholders in identifying shared or diverging interests, and facilitate joint problem solving. The same design features that enabled the tool to aid in decision making, however, also presented surprising challenges in certain circumstances by, for example, making it difficult for participants to discuss information that was not spatially represented on the map-based interface. The study also highlights the importance of the social context in which software is developed and implemented, suggesting that the relationship between the software development team and other participants may be as important as technical software design in shaping how DSTs add value. The paper concludes with considerations to inform the future use of DSTs in environmental decision-making processes.

  12. Implementation of dose monitoring software in the clinical routine. First experiences

    Energy Technology Data Exchange (ETDEWEB)

    Heilmaier, C.; Zuber, N.; Bruijns, B.; Weishaupt, D. [Stadtspital Triemli, Zurich (Switzerland). Dept. of Radiology and Nuclear Medicine; Ceyrolle, C. [DoseWatch, GE Healthcare, Buc (France)

    2016-01-15

    Radiation exposure of the public as a result of medical imaging has significantly increased during the last decades. To have a tool to register and control patient dose exposure, we implemented dose monitoring software at our institution and first connected our computed tomography (CT) scanners. CT dose data from July 2014 to February 2015 was retrospectively analyzed using dose monitoring software. We evaluated a number of scans above predefined dose thresholds (''alerts''), assessed reasons for alerts and compared data of two CT scanners, one located close to the emergency room (''emergency CT scanner'') and one mainly used on an outpatient basis (''clinical routine CT scanner''). To check for statistically significant differences between scanners, chi-square-tests were performed. A total of 8883 scans were acquired (clinical routine CT scanner, n = 3415; emergency CT scanner, n = 5468) during which 316 alerts were encountered (alert quota, 4 %). The overall alert quota ranged from 2 - 5 % with significantly higher values for the clinical routine CT scanner. Reasons for alerts were high BMI (51 %), patient off-centering (24 %), scan repetition (11 %), orthopedic hardware (9 %), or other (5 %). Scan repetition was necessary significantly more often with the emergency CT scanner (p = 0.019), while high BMI, off-centering and orthopedic hardware were more frequently seen with the clinical routine CT scanner (for all, p < 0.05). There was a good correlation between high body weight and dose above threshold (r = 0.585). Implementation of dose monitoring software in the clinical routine was successfully accomplished and provides important information regarding patient radiation protection.

  13. Initial Experience with the Utility of Infrared Diode Laser in Kaduna ...

    African Journals Online (AJOL)

    Our initial clinical experience with the use of a diode laser in the treatment of some retinovascular conditions and refractory glaucoma in some black patients in Kaduna, Nigeria. Methods: All the 32 eyes of 26 patients treated with diode laser photocoagulation between September 1997 and September 1999, were studied ...

  14. Digital Storytelling for Inclusive Education: An Experience in Initial Teacher Training

    Science.gov (United States)

    Lazzari, Marco

    2016-01-01

    We present an experience of digital storytelling conducted as part of a course for initial teacher training. The students of a special education course produced a digital story as partial fulfillment of their distance learning assignment. We describe the structure of the work completed by the students and discuss the results of a questionnaire…

  15. Adverse events in pediatric cardiac catheterization: Initial experience of Sohag university hospital

    Directory of Open Access Journals (Sweden)

    Safaa Husein Ali

    2016-03-01

    Conclusions: Pediatric cardiac catheterization by well trained team of pediatric cardiologists in a new center is effective. The rate of occurrence of AEs approximated to those which are reported by various interventional pediatric cardiology centers around the world. The lower body weight and the second year of initial experience are risk factors for occurrence of AE.

  16. Initiating Transdisciplinarity in Academic Case Study Teaching: Experiences from a Regional Development Project in Salzburg, Austria

    Science.gov (United States)

    Muhar, Andreas; Vilsmaier, Ulli; Glanzer, Michaela; Freyer, Bernhard

    2006-01-01

    Purpose: The purpose of this paper is to describe experiences with the initiation of transdisciplinarity in academic case study teaching with special reference to regional planning, based on the case study "Leben 2014 (Life 2014)--perspectives for regional development in the national park region Ober-pinz-gau, Salzburg".…

  17. "Elite" Career-Changers and Their Experience of Initial Teacher Education

    Science.gov (United States)

    Wilkins, Chris

    2017-01-01

    This study explores the motivation of "high-status" professionals to change career and enter teaching, and their experience of undertaking initial teacher education (ITE) programmes in England. The study builds on previous research which found that career-changers are disproportionately more likely to fail to complete their ITE studies,…

  18. The Year-Two Decline: Exploring the Incremental Experiences of a 1:1 Technology Initiative

    Science.gov (United States)

    Swallow, Meredith

    2015-01-01

    Reports on one-to-one (1:1) technology initiatives emphasize overall favorable results; however, comprehensive multiyear studies looked at understate the progressive experiences of teachers and students. A small body of research suggested the second year of 1:1 technology programs manifested difficulties and struggles which significantly…

  19. Initial Experience with the Extracorporeal HIFU Knife with 49 Patients: Japanese Experience

    Science.gov (United States)

    Ganaha, F.; Okuno, T.; Lee, C. O.; Shimizu, T.; Osako, K.; Oka, S.; Lee, K. H.; Chen, W. Z.; Zhu, H.; Park, S. H.; Qi, Z.; Shi, D.; Song, H. S.

    2005-03-01

    Forty nine patients with 63 tumours were treated with the Chongqing Haifu knife, as an adjunct to intra-arterial chemoinfusion. Treatment targets included breast (20 lesions), liver (16), bone (8), lymph-node (6), soft tissue (4), lung and pleura (4), pancreas (2), kidney (2) and adrenal gland (1). Follow-up contrast MRI was performed at 3 weeks to assess the effects of HIFU ablation. All cases completed the planned treatment. Of 25 lesions treated with the intention of complete tumour ablation, complete necrosis was obtained in 19 lesions (76%) including 4 secondary success cases. Among 32 lesions having partial and palliative treatment, tumour size was decreased in 6 lesions (21%), and good pain control was obtained in 6 out of 7 patients (86%). Skin injury was the most common complication after HIFU (16%), and was mostly a superficial dermal burn that did not necessitate any treatment. However, there was one patient with deep skin injury at an operation scar which resulted in skin perforation. Other adverse events included soft tissue swelling, prolonged fever, anorexia, persistent pain, shortness of the breath, sacroiliac joint fracture and prolonged diarrhoea. In our limited experience, superficial lesions (e.g. breast cancer, bone, soft tissue, lymph-node and pleural metastasis) appear to be good candidates for HIFU treatment. There appears to be a role for the HIFU knife in pain control for patients with bone metastasis and pancreatic cancer.

  20. A top-down strategy to reverse architecting execution views for a large and complex software-intensive system : An experience report

    NARCIS (Netherlands)

    Callo Arias, Trosky B.; Avgeriou, Paris; America, Pierre; Blom, Krelis; Bachynskyy, Sergiy

    2011-01-01

    This article is an experience report about the application of a top-down strategy to use and embed an architecture reconstruction approach in the incremental software development process of the Philips MRI scanner, a representative large and complex software-intensive system. The approach is an

  1. The experience of software development for bronchologist assistance during transbronchial biopsy

    Science.gov (United States)

    Shibaev, V. A.; Eremina, E. K.; Limanovskaia, O. V.; Khlebnikov, N. A.; Obabkov, I. N.; Filatowa, E. A.

    2017-09-01

    The nodules form in the lungs in case of disseminated diseases. The lesion biopsy is needed for the establishment of the correct diagnosis and for the creation of the treatment plan. The one of the methods of biopsy sampling is the transbronchial biopsy. The bronchologists who conduct such procedures are faced with the number of problems. For example, the inability to visual determination of the nodule position during the procedure leads to a high probability of sampling the healthy tissue. The software was developed to solve this and some other problems. It would allow a specialist to plan a future procedure. The program visualizes the lung parenchyma, the airway tree and the nodules. The bronchologist can choose the optimal place for biopsy sampling as well as the optimal target for the bronchoscope needle introduction.

  2. Multi-Country Experience in Delivering a Joint Course on Software Engineering – Numerical Results

    Directory of Open Access Journals (Sweden)

    Zoran Budimac1, 1, 1, 2, 3, and 3

    2014-02-01

    Full Text Available A joint course, created as a result of a project under the auspices of the ‘Stability Pact of South-Eastern Europe’ and DAAD, has been conducted in several Balkan countries: in Novi Sad, Serbia, for the last six years in several different forms, in Skopje, FYR of Macedonia, for two years, for several types of students, and in Tirana, Albania, in the form of a crash, seven-day course, for the last two years. In this paper, we will put an emphasis on the assessment methods used within these courses, and compare them with the ‘original’ course that has been conducted at the Humboldt University in Berlin for almost a decade. Having a good environment for comparisons we draw some conclusions about teaching software engineering in different environments.

  3. Promoting linguistic complexity, greater message length and ease of engagement in email writing in people with aphasia: initial evidence from a study utilizing assistive writing software.

    Science.gov (United States)

    Thiel, Lindsey; Sage, Karen; Conroy, Paul

    2017-01-01

    Improving email writing in people with aphasia could enhance their ability to communicate, promote interaction and reduce isolation. Spelling therapies have been effective in improving single-word writing. However, there has been limited evidence on how to achieve changes to everyday writing tasks such as email writing in people with aphasia. One potential area that has been largely unexplored in the literature is the potential use of assistive writing technologies, despite some initial evidence that assistive writing software use can lead to qualitative and quantitative improvements to spontaneous writing. This within-participants case series design study aimed to investigate the effects of using assistive writing software to improve email writing in participants with dysgraphia related to aphasia. Eight participants worked through a hierarchy of writing tasks of increasing complexity within broad topic areas that incorporate the spheres of writing need of the participants: writing for domestic needs, writing for social needs and writing for business/administrative needs. Through completing these tasks, participants had the opportunity to use the various functions of the software, such as predictive writing, word banks and text to speech. Therapy also included training and practice in basic computer and email skills to encourage increased independence. Outcome measures included email skills, keyboard skills, email writing and written picture description tasks, and a perception of disability assessment. Four of the eight participants showed statistically significant improvements to spelling accuracy within emails when using the software. At a group level there was a significant increase in word length with the software; while four participants showed noteworthy changes to the range of word classes used. Enhanced independence in email use and improvements in participants' perceptions of their writing skills were also noted. This study provided some initial evidence

  4. Create, share and learn. Experiences with free software, free culture and collaboration in formal and non formal education in Colombia

    OpenAIRE

    Medina Cardona, Luis Fernando

    2012-01-01

    New media technologies, specially software have been of great impact in modern society.The combination of computer/software/networks as creative machines is present in everyday life. This article is focused in this interactions specially from the perspective of free open source software (FOSS). In doing so, the influence of its values is traced from the original hacker culture ethics to the free software four freedoms, showing a software explained culture as in the software studies discipline...

  5. BFPTool: a software tool for analysis of Biomembrane Force Probe experiments.

    Science.gov (United States)

    Šmít, Daniel; Fouquet, Coralie; Doulazmi, Mohamed; Pincet, Frédéric; Trembleau, Alain; Zapotocky, Martin

    2017-01-01

    The Biomembrane Force Probe is an approachable experimental technique commonly used for single-molecule force spectroscopy and experiments on biological interfaces. The technique operates in the range of forces from 0.1 pN to 1000 pN. Experiments are typically repeated many times, conditions are often not optimal, the captured video can be unstable and lose focus; this makes efficient analysis challenging, while out-of-the-box non-proprietary solutions are not freely available. This dedicated tool was developed to integrate and simplify the image processing and analysis of videomicroscopy recordings from BFP experiments. A novel processing feature, allowing the tracking of the pipette, was incorporated to address a limitation of preceding methods. Emphasis was placed on versatility and comprehensible user interface implemented in a graphical form. An integrated analytical tool was implemented to provide a faster, simpler and more convenient way to process and analyse BFP experiments.

  6. Agile User Experience Development in a Large Software Organization: Good Expertise but Limited Impact

    OpenAIRE

    Kuusinen, Kati; Mikkonen, Tommi; Pakarinen, Santtu

    2012-01-01

    Part 2: Full Papers; International audience; While Agile methods were originally introduced for small, tightly coupled teams, leaner ways of working are becoming a practical method to run entire enterprises. As the emphasis of user experience work has inherently been on the early phases before starting the development, it also needs to be adapted to the Agile way of working. To improve the current practices in Agile user experience work, we determined the present state of a multi-continental ...

  7. Use of iodine-based contrast media in digital full-field mammography--initial experience.

    Science.gov (United States)

    Diekmann, F; Diekmann, S; Taupitz, M; Bick, U; Winzer, K-J; Hüttner, C; Muller, S; Jeunehomme, F; Hamm, B

    2003-03-01

    To investigate the use of iodine-based contrast media in digital full-field mammography. After performing initial phantom studies, seven patients underwent digital mammography (Senographe 2000D, GE Medical Systems, Milwaukee, USA) using a specially filtered beam before as well as 60, 120, and 180 seconds after injection of 80 ml of iodine contrast medium (Ultravist 370, Schering AG, Germany). The precontrast mammograms were then subtracted from the postcontrast mammograms and the resulting images compared with a contrast-enhanced dynamic MRI study, performed on all women. Contrast medium accumulation within the tumors was visualized with a good quality in all cases. The conditions under which successful contrast-enhanced digital mammography can be performed were determined in phantom studies. Contrast-enhanced digital mammography has a potential for improving the visualization of breast tumors in mammography using special beam filtering, adjusted x-ray parameters, proper timing, and suitable subtraction software.

  8. EXPERIENCE OF USING «OPEN JOURNAL SYSTEMS» SOFTWARE PLATFORM FOR INFORMATION SUPPORT OF SCIENTIFIC AND EDUCATIONAL ACTIVITY

    Directory of Open Access Journals (Sweden)

    Oleg M. Spirin

    2017-10-01

    Full Text Available The article deals with the foreign and domestic experience of using the Open Journal Systems (OJS software platform for informational support of scientific and educational activities, in particular: a as a means of publicizing and disseminating the results of scientific research; b for creating and maintaining repositories of libraries of higher educational establishments; c for developing the scientific and educational space of an educational establishments; d as a cloud-based service for the preservation and access to scientific resources; e for information support in organization of student training; and f for deployment of student journals. As a result of the analysis of scientific periodicals of Ukraine in the field of psychological and pedagogical sciences, the scientific journals on the basis of Open Journal Systems are identified. The experience of support the electronic scientific journal «Information Technologies and Learning Tools» (http://journal.iitta.gov.ua is presented separately.

  9. Development of energy scanning software to facilitate MAD experiment at PX-BL21, Indus-2 synchrotron

    Science.gov (United States)

    Dwivedi, Abhilash; Kumar, Ashwani; Ghosh, Biplab; Poswal, H. K.; Makde, Ravindra; Sharma, Surinder M.

    2017-05-01

    The protein crystallography beamline (PX-BL 21) at Indus-2 synchrotron (RRCAT, Indore) is dedicated for structure determination of macromolecules. For solving the phase problem in structure determination of macromolecules, MAD (Multi-Wavelength Anomalous Diffraction) scan is one of the well established methods. This scan requires a precise measurement of absorption data at or near the absorption edge of doped heavy atom for different wavelengths of X-rays. Software for absorption edge scanning using fluorescence detector and double crystal monochromator has been developed and deployed at PX-BL21. MAD experiment of a protein sample has been recorded and analyzed. With this important development, PX-BL21 is now fully equipped to perform anomalous diffraction experiments with single crystal protein samples.

  10. IsoDesign: a software for optimizing the design of 13C-metabolic flux analysis experiments.

    Science.gov (United States)

    Millard, Pierre; Sokol, Serguei; Letisse, Fabien; Portais, Jean-Charles

    2014-01-01

    The growing demand for (13) C-metabolic flux analysis ((13) C-MFA) in the field of metabolic engineering and systems biology is driving the need to rationalize expensive and time-consuming (13) C-labeling experiments. Experimental design is a key step in improving both the number of fluxes that can be calculated from a set of isotopic data and the precision of flux values. We present IsoDesign, a software that enables these parameters to be maximized by optimizing the isotopic composition of the label input. It can be applied to (13) C-MFA investigations using a broad panel of analytical tools (MS, MS/MS, (1) H NMR, (13) C NMR, etc.) individually or in combination. It includes a visualization module to intuitively select the optimal label input depending on the biological question to be addressed. Applications of IsoDesign are described, with an example of the entire (13) C-MFA workflow from the experimental design to the flux map including important practical considerations. IsoDesign makes the experimental design of (13) C-MFA experiments more accessible to a wider biological community. IsoDesign is distributed under an open source license at http://metasys.insa-toulouse.fr/software/isodes/ © 2013 Wiley Periodicals, Inc.

  11. initMIP-Antarctica: An ice sheet model initialization experiment of ISMIP6

    Science.gov (United States)

    Seroussi, H. L.; Nowicki, S.; Payne, A. J.; Larour, E. Y.; Abe-Ouchi, A.; Goelzer, H.; Gregory, J. M.; Lipscomb, W. H.; Shepherd, A.

    2016-12-01

    ISMIP6 (Ice Sheet Model Intercomparision Project for CMIP6) is the primary activity within the Coupled Model Intercomparison Project - phase 6 (CMIP6) focusing on the Greenland and Antarctic Ice Sheets. Ice sheet model simulations are strongly influenced by their initial conditions, but the impact of these conditions on simulations of ice sheet evolution over the next couple centuries remains poorly understood. To better understand this impact and the associated error, an initial intercompation exercice (initMIP) has been designed to compare, evaluate and improve initialization procedures and estimate their impact on century scale simulations. Following the initMIP-Greenland, a new initMIP-Antarctica has been designed to explore uncertainty associated with model initialization and spin-up and to evaluate initialization procedures. It consists of a set of three forward experiments of the Antarctic Ice Sheet that are each run for one hundred years: i) a control run (ctrl), ii) a surface mass balance anomaly run (asmb) and iii) a basal melt anomaly applied under the floating ice 30 (abmb) of the Antarctic Ice Sheet. All other model parameters are the same as those used for the initialization procedure. In this study, we present preliminary results of initMIP-Antarctica performed by different modeling groups and highlight the similarities and differences observed in the different simulations.

  12. The ATLAS High Level Trigger Configuration and Steering Software: Experience with 7 TeV Collisions

    CERN Document Server

    George, S; The ATLAS collaboration

    2010-01-01

    In 2010 ATLAS has seen the first proton-proton collisions at 7 TeV. Later this year a collision rate of nearly 10 MHz is expected. Events of potential interest for physics analysis are selected by a three-level trigger system, with a final recording rate of about 200 Hz. The first level (L1) is implemented in customised hardware, the two levels of the high level trigger (HLT) are software triggers. The selection is described by the Trigger Configuration in the form of menus, each of which contains more than 500 signatures. Each signature corresponds to a chain of algorithms which reconstruct and refine specific event features. The HLT Steering receives information from the Configuration system, dynamically creates chains and controls the execution of algorithms and flow of information during event processing. The Steering tests each signature on L1-accepted events, and those satisfying one or more test are recorded for later analysis. To save execution time, the Steering has a facility to cache results, avoid...

  13. Academic summary: a mediation experience with the genre in initial teacher training

    Directory of Open Access Journals (Sweden)

    Rubia Mara Bragagnollo

    2014-02-01

    Full Text Available Current research deals with the constitution of writing in initial teacher training when employing the Academic Summary genre. The mediation process and the tools involved are focused. Analysis is based on the concepts of interaction and writing discussed by Vygotsky (1991, Bakhtin and Volochinov (2006 and Bakhtin (2003 within the socio-interaction and enunciation perspectives of language and the notion of discursive genres. A mediation experience in the writing of academic summaries with teachers in initial training at the university and the highlighting of mediation in this process are provided. The experience occurred with first year students of the Language and Literature undergraduate course at a government-run university in Paraná in 2009. Employing the  qualitative-interpretative approach in the analysis of one summary, the advantages of mediation activities in writing process of the genre are demonstrated.

  14. Applying Peer Reviews in Software Engineering Education: An Experiment and Lessons Learned

    Science.gov (United States)

    Garousi, V.

    2010-01-01

    Based on the demonstrated value of peer reviews in the engineering industry, numerous industry experts have listed it at the top of the list of desirable development practices. Experience has shown that problems (defects) are eliminated earlier if a development process incorporates peer reviews and that these reviews are as effective as or even…

  15. Migration Experience and Premarital Sexual Initiation in Urban Kenya: An Event History Analysis

    Science.gov (United States)

    Luke, Nancy; Xu, Hongwei; Mberu, Blessing U.; Goldberg, Rachel E.

    2013-01-01

    Migration during the formative adolescent years can affect important life-course transitions, including the initiation of sexual activity. In this study, we use life history calendar data to investigate the relationship between changes in residence and timing of premarital sexual debut among young people in urban Kenya. By age 18, 64 percent of respondents had initiated premarital sex, and 45 percent had moved at least once between the ages of 12 and 18. Results of the event history analysis show that girls and boys who move during early adolescence experience the earliest onset of sexual activity. For adolescent girls, however, other dimensions of migration provide protective effects, with greater numbers of residential changes and residential changes in the last one to three months associated with later sexual initiation. To support young people’s ability to navigate the social, economic, and sexual environments that accompany residential change, researchers and policymakers should consider how various dimensions of migration affect sexual activity. PMID:23175950

  16. Migration experience and premarital sexual initiation in urban Kenya: an event history analysis.

    Science.gov (United States)

    Luke, Nancy; Xu, Hongwei; Mberu, Blessing U; Goldberg, Rachel E

    2012-06-01

    Migration during the formative adolescent years can affect important life-course transitions, including the initiation of sexual activity. In this study, we use life history calendar data to investigate the relationship between changes in residence and timing of premarital sexual debut among young people in urban Kenya. By age 18, 64 percent of respondents had initiated premarital sex, and 45 percent had moved at least once between the ages of 12 and 18. Results of the event history analysis show that girls and boys who move during early adolescence experience the earliest onset of sexual activity. For adolescent girls, however, other dimensions of migration provide protective effects, with greater numbers of residential changes and residential changes in the last one to three months associated with later sexual initiation. To support young people's ability to navigate the social, economic, and sexual environments that accompany residential change, researchers and policymakers should consider how various dimensions of migration affect sexual activity.

  17. Initial experience with a first-to-market member accountability-based insurance product.

    Science.gov (United States)

    Woll, Douglas R; Nelson, David R

    2010-10-01

    We describe the initial experience with a first-to-market health insurance product design based on principles of both member and purchaser accountability. Two benefit levels were offered, enhanced and standard. Qualification for the enhanced benefit level was obtained through members' commitment to follow their physicians' recommended treatment plan. Employers were offered a discount of 10% in exchange for offering this new product and promoting a healthy work environment. Membership in the product grew beyond expectations, and several health improvements were noted.

  18. SPINAL CORD STIMULATION IN TREATMENT OF THE NEUROPATHIC PAIN SYNDROMES: INITIAL EXPERIENCE

    Directory of Open Access Journals (Sweden)

    D. A. Rzaev

    2010-01-01

    Full Text Available In the article initial experience of spinal cord stimulation for chronic pain syndromes is described. The trial was done for 62 patients, in 52 cases trial was successful and subcutaneous pulse generator were implanated. Maximal follow-up is 26 months. The level of pain evaluates at VAS. Permanent pain-relieve results were achieved in 46 patients (74,2%. These results correspond to literature data.

  19. Japan's Initial Experience with Technical Development Cooperation in Basic Education : A Case in Ghana

    OpenAIRE

    Kuroda, Norihiro

    2005-01-01

    This article describes several features of an in-service teacher training (INSET) project for science and mathematics teachers in basic education (grades 4 - 9) in Ghana. This project is an example of Japan's initial experience with technical development cooperation in basic education. Some of the major features of the project are as follows. 1) As a new comer in technical cooperation in basic education Japan was very careful about where to intervene and finally chose science and mathemat...

  20. E-LEARNING EXPERIENCE WITH ARTIFICIAL INTELLIGENCE SUPPORTED SOFTWARE: An International Application on English Language Courses

    OpenAIRE

    Kose, Utku; Arslan, Ahmet

    2015-01-01

    Nowadays, artificial intelligence supported e-learning scenarios are widely employed by educational institutions in order to ensure better teaching and learning experiences along educational activities. In the context of performed scientific studies, positive results often encourage such institutions to apply their intelligent e-learning systems on different types of courses and report advantages of artificial intelligent in especially education field. It seems that the future of education w...

  1. Thermophysical Property Estimation by Transient Experiments: The Effect of a Biased Initial Temperature Distribution

    Directory of Open Access Journals (Sweden)

    Federico Scarpa

    2015-01-01

    Full Text Available The identification of thermophysical properties of materials in dynamic experiments can be conveniently performed by the inverse solution of the associated heat conduction problem (IHCP. The inverse technique demands the knowledge of the initial temperature distribution within the material. As only a limited number of temperature sensors (or no sensor at all are arranged inside the test specimen, the knowledge of the initial temperature distribution is affected by some uncertainty. This uncertainty, together with other possible sources of bias in the experimental procedure, will propagate in the estimation process and the accuracy of the reconstructed thermophysical property values could deteriorate. In this work the effect on the estimated thermophysical properties due to errors in the initial temperature distribution is investigated along with a practical method to quantify this effect. Furthermore, a technique for compensating this kind of bias is proposed. The method consists in including the initial temperature distribution among the unknown functions to be estimated. In this way the effect of the initial bias is removed and the accuracy of the identified thermophysical property values is highly improved.

  2. Kinetic Simulations - Oshun (Vlasov-Fokker-Planck) and PIC (Osiris) - Physics and Open Source Software In The UCLA PICKSE Initiative

    Science.gov (United States)

    Tableman, Adam; Tzoufras, Michail; Fonseca, Ricardo; Mori, W. B.

    2017-10-01

    We present physics results and general updates for two plasma kinetic simulation codes developed under the UCLA PICKSE initiative. We also discuss the issues around making these codes open source such that they can be used (and contributed too) by a large audience. The first code discussed is Oshun - a Vlasov-Fokker-Planck (VFP) code. Recent simulations with the VFP code OSHUN will be presented for all of the aforementioned problems. The algorithmic improvements that have facilitated these studies will be also be discussed. The second code discussed is the PIC code Osiris. Osiris is a widely respected code used in hundreds of papers. Osiris was first developed for laser-plasma interactions but has grown into a robust framework covering most areas of plasma research. One defining feature of Osiris is that it is highly optimized for a variety of hardware configurations and scales linearly over 1 million + CPU nodes. We will discuss the recently released version 4.0 written in modern, fully-object oriented FORTRAN.

  3. Patients' Experiences of Performing Self-care of Stomas in the Initial Postoperative Period.

    Science.gov (United States)

    Lim, Siew Hoon; Chan, Sally Wai Chi; He, Hong-Gu

    2015-01-01

    With the loss of an important bodily function and the distortion in body image, a stoma patient experiences physical, psychological, and social changes. With limited current studies exploring experiences of patients in the management of their stoma, there is a need to explore their experiences, their needs, and factors that influence their self-management. The aim of this study was to investigate patients' experiences of performing self-care of stomas in the initial postoperative period. This study adopted a descriptive qualitative approach from the interpretive paradigm. Semistructured interviews were conducted with 12 patients 1 month postoperatively in a colorectal ward in a hospital in Singapore. Thematic analysis was applied to the interview data. Five themes were identified: process of acceptance and self-management of stoma, physical limitations, psychological reactions, social support, and need for timely and sufficient stoma preparation and education. This study highlights the importance of health professionals' role in helping patients adjust preoperatively and postoperatively and accept the presence of a stoma. Health professionals need to be aware of the physical, psychological, and social impact of stoma on patients in the initial 30-day postoperative period. Research findings informed the type and level of assistance and support to be offered to patients by nurses and the importance of encouraging patients to be involved in stoma care at an early stage, which will ultimately contribute to effective and independent self-management. Patients can be prepared preoperatively to reduce the psychological and social impact of stoma after creation of their stoma.

  4. Software engineering the current practice

    CERN Document Server

    Rajlich, Vaclav

    2011-01-01

    INTRODUCTION History of Software EngineeringSoftware PropertiesOrigins of SoftwareBirth of Software EngineeringThird Paradigm: Iterative ApproachSoftware Life Span ModelsStaged ModelVariants of Staged ModelSoftware Technologies Programming Languages and CompilersObject-Oriented TechnologyVersion Control SystemSoftware ModelsClass DiagramsUML Activity DiagramsClass Dependency Graphs and ContractsSOFTWARE CHANGEIntroduction to Software ChangeCharacteristics of Software ChangePhases of Software ChangeRequirements and Their ElicitationRequirements Analysis and Change InitiationConcepts and Concept

  5. Development of training-related health care software by a team of clinical educators: their experience, from conception to piloting

    Directory of Open Access Journals (Sweden)

    ap Dafydd D

    2016-11-01

    Full Text Available Derfel ap Dafydd,1 Ruth Williamson,2 Philip Blunt,3 Dominic M Blunt4 1Department of Radiology, Royal Marsden NHS Foundation Trust, London, 2Imaging Department, Royal Bornemouth Hospital, Bornemouth, 3Savernake IT Ltd, Marlborough, 4Imaging Department, Imperial College Healthcare NHS Trust, London, UK Abstract: The difficulties of producing useful, bespoke, and affordable information technology systems for large health care organizations are well publicized, following several high-profile endeavors in the UK. This article describes the experience of a small group of clinical radiologists and their collaborators in producing an information technology system – from conception to piloting. This system, called Trainee Tracker, enables automated target date recalculation of trainee milestones, depending on their work patterns and other individual circumstances. It utilizes an automated email alert system to notify the educational supervisors and trainees of approaching and elapsed target dates, in order to identify trainees in difficulty early and address their training needs accordingly. The challenges and advantages, both common to and contrasting with larger-scale projects, are also considered. The benefits of the development team’s “agile” approach to software development and the lessons learned will be of interest to medical educators, particularly those with expertise in e-portfolios and other training-related software. Keywords: training, appraisal, ARCP, Annual Review of Clinical Progression, portfolio, trainer

  6. Experiment Design Regularization-Based Hardware/Software Codesign for Real-Time Enhanced Imaging in Uncertain Remote Sensing Environment

    Directory of Open Access Journals (Sweden)

    Castillo Atoche A

    2010-01-01

    Full Text Available A new aggregated Hardware/Software (HW/SW codesign approach to optimization of the digital signal processing techniques for enhanced imaging with real-world uncertain remote sensing (RS data based on the concept of descriptive experiment design regularization (DEDR is addressed. We consider the applications of the developed approach to typical single-look synthetic aperture radar (SAR imaging systems operating in the real-world uncertain RS scenarios. The software design is aimed at the algorithmic-level decrease of the computational load of the large-scale SAR image enhancement tasks. The innovative algorithmic idea is to incorporate into the DEDR-optimized fixed-point iterative reconstruction/enhancement procedure the convex convergence enforcement regularization via constructing the proper multilevel projections onto convex sets (POCS in the solution domain. The hardware design is performed via systolic array computing based on a Xilinx Field Programmable Gate Array (FPGA XC4VSX35-10ff668 and is aimed at implementing the unified DEDR-POCS image enhancement/reconstruction procedures in a computationally efficient multi-level parallel fashion that meets the (near real-time image processing requirements. Finally, we comment on the simulation results indicative of the significantly increased performance efficiency both in resolution enhancement and in computational complexity reduction metrics gained with the proposed aggregated HW/SW co-design approach.

  7. AUX: a scripting language for auditory signal processing and software packages for psychoacoustic experiments and education.

    Science.gov (United States)

    Kwon, Bomjun J

    2012-06-01

    This article introduces AUX (AUditory syntaX), a scripting syntax specifically designed to describe auditory signals and processing, to the members of the behavioral research community. The syntax is based on descriptive function names and intuitive operators suitable for researchers and students without substantial training in programming, who wish to generate and examine sound signals using a written script. In this article, the essence of AUX is discussed and practical examples of AUX scripts specifying various signals are illustrated. Additionally, two accompanying Windows-based programs and development libraries are described. AUX Viewer is a program that generates, visualizes, and plays sounds specified in AUX. AUX Viewer can also be used for class demonstrations or presentations. Another program, Psycon, allows a wide range of sound signals to be used as stimuli in common psychophysical testing paradigms, such as the adaptive procedure, the method of constant stimuli, and the method of adjustment. AUX Library is also provided, so that researchers can develop their own programs utilizing AUX. The philosophical basis of AUX is to separate signal generation from the user interface needed for experiments. AUX scripts are portable and reusable; they can be shared by other researchers, regardless of differences in actual AUX-based programs, and reused for future experiments. In short, the use of AUX can be potentially beneficial to all members of the research community-both those with programming backgrounds and those without.

  8. Influences of family structure experiences on the risk of premarital sexual initiation during adolescence in Cameroon.

    Science.gov (United States)

    Sidze, Estelle Monique; Defo, Barthélemy Kuate

    2013-12-01

    The link between family structure experiences and premarital sexual initiation in sub-Saharan African settings has been investigated using primarily the socialization perspective. This article tests additional hypotheses using the perspectives of change and duration of exposure. The analyses are based on time-dependent retrospective data on family living arrangements from a sample of 1182 individuals aged 12-24 years old, drawn from the Cameroon Family and Health Survey. From the socialization perspective for both females and males: living without both biological parents does not necessarily increase the probability of premarital sexual initiation during adolescence; the timing of family structure experiences is an important factor to consider in life course transitions; and other relatives play a protective role during adolescence, especially among females living in mother-only families. Findings also provide some support for the instability and change hypothesis as well as for the duration of exposure conjecture: a change from other family structure types to a both biological parents structure between age 6 and age 12 (change perspective) and living with the biological mother only at all the time (duration of exposure perspective) are associated with lower risks of premarital sexual initiation during adolescence among females. Our results have implications for preventing risky sexual behaviours during adolescence. Copyright © 2013 Elsevier Ltd. All rights reserved.

  9. Initial Scaling Studies and Conceptual Thermal Fluids Experiments for the Prismatic NGNP Point Design

    Energy Technology Data Exchange (ETDEWEB)

    D. M. McEligot; G. E. McCreery

    2004-09-01

    The objective of this report is to document the initial high temperature gas reactor scaling studies and conceptual experiment design for gas flow and heat transfer. The general approach of the project is to develop new benchmark experiments for assessment in parallel with CFD and coupled CFD/ATHENA/RELAP5-3D calculations for the same geometry. Two aspects of the complex flow in an NGNP are being addressed: (1) flow and thermal mixing in the lower plenum ("hot streaking" issue) and (2) turbulence and resulting temperature distributions in reactor cooling channels ("hot channel" issue). Current prismatic NGNP concepts are being examined to identify their proposed flow conditions and geometries over the range from normal operation to decay heat removal in a pressurized cooldown. Approximate analyses are being applied to determine key non-dimensional parameters and their magnitudes over this operating range. For normal operation, the flow in the coolant channels can be considered to be dominant forced convection with slight transverse property variation. The flow in the lower plenum can locally be considered to be a situation of multiple buoyant jets into a confined density-stratified crossflow -- with obstructions. Experiments are needed for the combined features of the lower plenum flows. Missing from the typical jet experiments are interactions with nearby circular posts and with vertical posts in the vicinity of vertical walls - with near stagnant surroundings at one extreme and significant crossflow at the other. Two heat transfer experiments are being considered. One addresses the "hot channel" problem, if necessary. The second experiment will treat heated jets entering a model plenum. Unheated MIR (Matched-Index-of-Refraction) experiments are first steps when the geometry is complicated. One does not want to use a computational technique which will not even handle constant properties properly. The MIR experiment will simulate flow features of the paths of jets

  10. Hardware and software development of a multichannel readout board named CARLOSrx for the ALICE experiment

    CERN Document Server

    Costa, Filippo

    2009-01-01

    ALICE, that is an experiment held at CERN using the LHC, is specialized in analyzing lead-ion collisions. ALICE will study the properties of quarkgluon plasma, a state of matter where quarks and gluons, under conditions of very high temperatures and densities, are no longer confined inside hadrons. Such a state of matter probably existed just after the Big Bang, before particles such as protons and neutrons were formed. The SDD detector, one of the ALICE subdetectors, is part of the ITS that is composed by 6 cylindrical layers with the innermost one attached to the beam pipe. The ITS tracks and identifies particles near the interaction point, it also aligns the tracks of the articles detected by more external detectors. The two ITS middle layers contain the whole 260 SDD detectors. A multichannel readout board, called CARLOSrx, receives at the same time the data coming from 12 SDD detectors. In total there are 24 CARLOSrx boards needed to read data coming from all the SDD modules (detector plus front end elec...

  11. Enabling Data Discovery and Reuse by Improving Software Usability:Data Science Experiences, Lessons, and Gaps

    Science.gov (United States)

    Rosati, A.; Yarmey, L.

    2014-12-01

    It is well understood that a good data scientist needs domain science, analysis, programming, and communication skills to create finished data products, visualizations, and reports. Articles and blogs tout the need for "expert" skill levels in domain knowledge, statistics, storytelling, graphic design, technology…and the list goes on. Since it seems impossible that one person would encompass all these skills, it is often suggested that data science be done by a team instead of an individual. This research into, and experience with, data product design offers an augmented definition - one that elevates relationships and engagement with the final user of a product. Essentially, no matter how fantastic or technically advanced a product appears, the intended audience of that product must be able to understand, use, and find value in the product in order for it to be considered a success. Usability is often misunderstood and seen as common sense or common knowledge, but it is actually an important and challenging piece of product development. This paper describes the National Snow and Ice Data Center's process to usability test the Arctic Data Explorer (ADE). The ADE is a federated data search tool for interdisciplinary Arctic science data that has been improved in features, appearance, functionality, and quality through a series of strategic and targeted usability testing and assessments. Based on the results, it is recommended that usability testing be incorporated into the skill set of each data science team.

  12. Internet-based virtual classroom and educational management software enhance students' didactic and clinical experiences in perfusion education programs.

    Science.gov (United States)

    Riley, Jeffrey B; Austin, Jon W; Holt, David W; Searles, Bruce E; Darling, Edward M

    2004-09-01

    A challenge faced by many university-based perfusion education (PE) programs is the need for student clinical rotations at hospital locations that are geographically disparate from the main educational campus. The problem has been addressed through the employment of distance-learning environments. The purpose of this educational study is to evaluate the effectiveness of this teaching model as it is applied to PE. Web-based virtual classroom (VC) environments and educational management system (EMS) software were implemented independently and as adjuncts to live, interactive Internet-based audio/video transmission from classroom to classroom in multiple university-based PE programs. These Internet environments have been used in a variety of ways including: 1) forum for communication between the university faculty, students, and preceptors at clinical sites, 2) didactic lectures from expert clinicians to students assigned to distant clinical sites, 3) small group problem-based-learning modules designed to enhance students analytical skills, and 4) conversion of traditional face-to-face lectures to asynchronous learning modules. Hypotheses and measures of student and faculty satisfaction, clinical experience, and learning outcomes are proposed, and some early student feedback was collected. For curricula that emphasize both didactic and clinical education, the use of Internet-based VC and EMS software provides significant advancements over traditional models. Recognized advantages include: 1) improved communications between the college faculty and the students and clinical preceptors, 2) enhanced access to a national network of clinical experts in specialized techniques, 3) expanded opportunity for student distant clinical rotations with continued didactic course work, and 4) improved continuity and consistency of clinical experiences between students through implementation of asynchronous learning modules. Students recognize the learning efficiency of on

  13. Neonatal extracorporeal membrane oxygenation: Initial experience of Hospital de São João

    OpenAIRE

    G. Rocha; P. Soares; T. Henriques-Coelho; J. Correia-Pinto; J. Monteiro; H. Guimarães; R. Roncon-Albuquerque, Jr.

    2014-01-01

    The purpose of this series is to report the initial ECMO experience of the Neonatal Intensive Care Unit of Hospital de São João. The first three clinical cases are reported. Case report 1: a 39 weeks gestational age girl with severe lung hypoplasia secondary to a bilateral congenital diaphragmatic hernia. Case report 2: a 39 weeks gestational age girl with a right congenital diaphragmatic hernia and a tracheal stenosis. Case report 3: a 34 weeks gestational age boy, with 61 days of life, with...

  14. Initial Experience with Sutureless Sorin Perceval S Aortic Prosthesis for the Treatment of Prosthetic Valve Endocarditis.

    Science.gov (United States)

    Lio, Antonio; Miceli, Antonio; Solinas, Marco; Glauber, Mattia

    2015-09-01

    The objective of this study is to evaluate results of the initial experience with sutureless Perceval S for active prosthetic valve endocarditis (PVE). From October 2012 to April 2014, f: ve patients underwent surgery for aortic PVE with Perceval S bioprosthesis. There was one in-hospital death (20%). Echocardiography performed at discharge showed excellent hemodynamic performance of Perceval S bioprosthesis. Aortic valve replacement with Perceval S sutureless valve in patients with PVE is a feasible and safe procedure, associated with low in-hospital mortality and good hemodynamic performance of the prosthesis. Georg Thieme Verlag KG Stuttgart · New York.

  15. Initial experience with implantation of novel dual layer flow-diverter device FRED

    OpenAIRE

    Poncyljusz, Wojciech; Sagan, Leszek; Safranow, Krzysztof; Ra?, Monika

    2013-01-01

    Flow-diverting stents can help treat complex and wide-necked cerebral aneurysms. The aim of the study was to evaluate initial experiences related to the safety and effectiveness of eight aneurysms treated with a new dual layer coverage designed flow-diverter device. In 2012 Fred flow-diverter devices were used to treat 8 unruptured wide neck (dome-neck ratio ? 1.5) and sidewall aneurysms in 6 patients. All aneurysms were located in the anterior circulation on the internal carotid artery (ICA)...

  16. Initial Experiences of Simultaneous Laparoscopic Resection of Colorectal Cancer and Liver Metastases

    Directory of Open Access Journals (Sweden)

    L. T. Hoekstra

    2012-01-01

    Full Text Available Introduction. Simultaneous resection of primary colorectal carcinoma (CRC and synchronous liver metastases (SLMs is subject of debate with respect to morbidity in comparison to staged resection. The aim of this study was to evaluate our initial experience with this approach. Methods. Five patients with primary CRC and a clinical diagnosis of SLM underwent combined laparoscopic colorectal and liver surgery. Patient and tumor characteristics, operative variables, and postoperative outcomes were evaluated retrospectively. Results. The primary tumor was located in the colon in two patients and in the rectum in three patients. The SLM was solitary in four patients and multiple in the remaining patient. Surgical approach was total laparoscopic (2 patients or hand-assisted laparoscopic (3 patients. The midline umbilical or transverse suprapubic incision created for the hand port and/or extraction of the specimen varied between 5 and 10 cm. Median operation time was 303 (range 151–384 minutes with a total blood loss of 700 (range 200–850 mL. Postoperative hospital stay was 5, 5, 9, 14, and 30 days. An R0 resection was achieved in all patients. Conclusions. From this initial single-center experience, simultaneous laparoscopic colorectal and liver resection appears to be feasible in selected patients with CRC and SLM, with satisfying short-term results.

  17. Intraoperative 3-tesla MRI in the management of paediatric cranial tumours - initial experience

    Energy Technology Data Exchange (ETDEWEB)

    Avula, Shivaram; Garlick, Deborah; Abernethy, Laurence J. [Alder Hey Children' s NHS Foundation Trust, Department of Radiology, Liverpool (United Kingdom); Mallucci, Connor L. [Alder Hey Children' s Hospital, Department of Neurosurgery, Liverpool (United Kingdom); Pizer, Barry [Alder Hey Children' s Hospital, Department of Oncology, Liverpool (United Kingdom); Crooks, Daniel [Walton Centre for Neurology and Neurosurgery, Department of Pathology, Liverpool (United Kingdom)

    2012-02-15

    Intraoperative MRI (ioMRI) has been gaining recognition because of its value in the neurosurgical management of cranial tumours. There is limited documentation of its value in children. To review the initial experience of a paediatric 3-Tesla ioMRI unit in the management of cranial tumours. Thirty-eight children underwent ioMRI during 40 cranial tumour resections using a 3-Tesla MR scanner co-located with the neurosurgical operating theatre. IoMRI was performed to assess the extent of tumour resection and/or to update neuronavigation. The intraoperative and follow-up scans, and the clinical records were reviewed. In 27/40 operations, complete resection was intended. IoMRI confirmed complete resection in 15/27 (56%). As a consequence, surgical resection was extended in 5/27 (19%). In 6/27 (22%), ioMRI was equivocal for residual tumour. In 13/40 (33%) operations, the surgical aim was to partially resect the tumour. In 7 of the 13 (54%), surgical resection was extended following ioMRI. In our initial experience, ioMRI has increased the rate of complete resection, with intraoperative surgical strategy being modified in 30% of procedures. Collaborative analysis of ioMRI by the radiologist and neurosurgeon is vital to avoid errors in interpretation. (orig.)

  18. Shock Initiation Experiments with Ignition and Growth Modeling on the HMX-Based Explosive LX-14

    Science.gov (United States)

    Vandersall, Kevin S.; Dehaven, Martin R.; Strickland, Shawn L.; Tarver, Craig M.; Springer, H. Keo; Cowan, Matt R.

    2017-06-01

    Shock initiation experiments on the HMX-based explosive LX-14 were performed to obtain in-situ pressure gauge data, characterize the run-distance-to-detonation behavior, and provide a basis for Ignition and Growth reactive flow modeling. A 101 mm diameter gas gun was utilized to initiate the explosive charges with manganin piezoresistive pressure gauge packages placed between sample disks pressed to different densities ( 1.57 or 1.83 g/cm3 that corresponds to 85 or 99% of theoretical maximum density (TMD), respectively). The shock sensitivity was found to increase with decreasing density as expected. Ignition and Growth model parameters were derived that yielded reasonable agreement with the experimental data at both initial densities. The shock sensitivity at the tested densities will be compared to prior work published on other HMX-based formulations. This work performed under the auspices of the U.S. Department of Energy by Lawrence Livermore National Laboratory under Contract DE-AC52-07NA27344. This work was funded in part by the Joint DoD-DOE Munitions Program.

  19. The Lusi seismic experiment: An initial study to understand the effect of seismic activity to Lusi

    Energy Technology Data Exchange (ETDEWEB)

    Karyono, E-mail: karyonosu@gmail.com [Agency for Meteorology, Climatology and Geophysics (BMKG), Jakarta (Indonesia); OSLO University (Norway); Padjadjaran University (UNPAD), Bandung (Indonesia); Mazzini, Adriano; Sugiharto, Anton [OSLO University (Norway); Lupi, Matteo [ETH Zurich (Switzerland); Syafri, Ildrem [Padjadjaran University (UNPAD), Bandung (Indonesia); Masturyono,; Rudiyanto, Ariska; Pranata, Bayu; Muzli,; Widodo, Handi Sulistyo; Sudrajat, Ajat [Agency for Meteorology, Climatology and Geophysics (BMKG), Jakarta (Indonesia)

    2015-04-24

    The spectacular Lumpur Sidoarjo (Lusi) eruption started in northeast Java on the 29 of May 2006 following a M6.3 earthquake striking the island [1,2]. Initially, several gas and mud eruption sites appeared along the reactivated strike-slip Watukosek fault system [3] and within weeks several villages were submerged by boiling mud. The most prominent eruption site was named Lusi. The Lusi seismic experiment is a project aims to begin a detailed study of seismicity around the Lusi area. In this initial phase we deploy 30 seismometers strategically distributed in the area around Lusi and along the Watukosek fault zone that stretches between Lusi and the Arjuno Welirang (AW) complex. The purpose of the initial monitoring is to conduct a preliminary seismic campaign aiming to identify the occurrence and the location of local seismic events in east Java particularly beneath Lusi.This network will locate small event that may not be captured by the existing BMKG network. It will be crucial to design the second phase of the seismic experiment that will consist of a local earthquake tomography of the Lusi-AW region and spatial and temporal variations of vp/vs ratios. The goal of this study is to understand how the seismicity occurring along the Sunda subduction zone affects to the behavior of the Lusi eruption. Our study will also provide a large dataset for a qualitative analysis of earthquake triggering studies, earthquake-volcano and earthquake-earthquake interactions. In this study, we will extract Green’s functions from ambient seismic noise data in order to image the shallow subsurface structure beneath LUSI area. The waveform cross-correlation technique will be apply to all of recordings of ambient seismic noise at 30 seismographic stations around the LUSI area. We use the dispersive behaviour of the retrieved Rayleigh waves to infer velocity structures in the shallow subsurface.

  20. Development of workflow planning software and a tracking study of the decay B± → J / Ψ at the D0 Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Evans, David Edward [Lancaster Univ. (United Kingdom)

    2003-09-01

    A description of the development of the mc_runjob software package used to manage large scale computing tasks for the D0 Experiment at Fermilab is presented, along with a review of the Digital Front End Trigger electronics and the software used to control them. A tracking study is performed on detector data to determine that the D0 Experiment can detect charged B mesons, and that these results are in accordance with current results. B mesons are found by searching for the decay channel B± → J / Ψ K± .

  1. Magnetic resonance image segmentation using semi-automated software for quantification of knee articular cartilage - initial evaluation of a technique for paired scans

    Energy Technology Data Exchange (ETDEWEB)

    Brem, M.H. [Brigham and Women' s Hospital, Department of Radiology, Boston, MA (United States); Friedrich-Alexander-University Erlangen Nurenberg, Division of Orthopaedic and Trauma Surgery, Department of Surgery, Erlangen (Germany); Lang, P.K.; Neumann, G.; Schlechtweg, P.M.; Yoshioka, H.; Pappas, G.; Duryea, J. [Brigham and Women' s Hospital, Department of Radiology, Boston, MA (United States); Schneider, E. [LLC, SciTrials, Rocky River, OH (United States); Cleveland Clinic, Imaging Institute, Cleveland, OH (United States); Jackson, R.; Yu, J. [Ohio State University, Diabetes and Metabolism and Radiology, Department of Endocrinology, Columbus, OH (United States); Eaton, C.B. [Center for Primary Care and Prevention and the Warren Alpert Medical School of Brown University, Memorial Hospital of Rhode Island, Providence, RI (United States); Hennig, F.F. [Friedrich-Alexander-University Erlangen Nurenberg, Division of Orthopaedic and Trauma Surgery, Department of Surgery, Erlangen (Germany)

    2009-05-15

    Software-based image analysis is important for studies of cartilage changes in knee osteoarthritis (OA). This study describes an evaluation of a semi-automated cartilage segmentation software tool capable of quantifying paired images for potential use in longitudinal studies of knee OA. We describe the methodology behind the analysis and demonstrate its use by determination of test-retest analysis precision of duplicate knee magnetic resonance imaging (MRI) data sets. Test-retest knee MR images of 12 subjects with a range of knee health were evaluated from the Osteoarthritis Initiative (OAI) pilot MR study. Each subject was removed from the magnet between the two scans. The 3D DESS (sagittal, 0.456 mm x 0.365 mm, 0.7 mm slice thickness, TR 16.5 ms, TE 4.7 ms) images were obtained on a 3-T Siemens Trio MR system with a USA Instruments quadrature transmit-receive extremity coil. Segmentation of one 3D-image series was first performed and then the corresponding retest series was segmented by viewing both image series concurrently in two adjacent windows. After manual registration of the series, the first segmentation cartilage outline served as an initial estimate for the second segmentation. We evaluated morphometric measures of the bone and cartilage surface area (tAB and AC), cartilage volume (VC), and mean thickness (ThC.me) for medial/lateral tibia (MT/LT), total femur (F) and patella (P). Test-retest reproducibility was assessed using the root-mean square coefficient of variation (RMS CV%). For the paired analyses, RMS CV % ranged from 0.9% to 1.2% for VC, from 0.3% to 0.7% for AC, from 0.6% to 2.7% for tAB and 0.8% to 1.5% for ThC.me. Paired image analysis improved the measurement precision of cartilage segmentation. Our results are in agreement with other publications supporting the use of paired analysis for longitudinal studies of knee OA. (orig.)

  2. The Carbon Dioxide Removal Model Intercomparison Project (CDR-MIP) Initial Results and Future Experiment Designs

    Science.gov (United States)

    Keller, D. P.; Scott, V.; Lenton, A.; Vaughan, N.

    2016-12-01

    Continued anthropogenic greenhouse gas emissions are changing the climate threatening "severe, pervasive and irreversible" impacts. Inadequate emissions reduction is resulting in increased attention on Climate Intervention (CI) - deliberate interventions to counter climate change that seek to either modify the Earth's radiation budget, or remove the primary greenhouse gas from the atmosphere - Carbon Dioxide Removal (CDR). The majority of future scenarios that do not exceed 2°C warming by 2100 include CDR methods. At present, there is little consensus on the efficacy and impacts of CDR and proposed CDR methods. In response, the Carbon Dioxide Removal Model Intercomparison Project (or CDR-MIP) has been initiated. This project brings together a suite of Earth System Models (ESMs) and Earth System Models of Intermediate Complexity (EMICS) in a common framework to explore the potential, risks, and challenges of CDR and different proposed CDR methods. The first set of CDR-MIP experiments investigate climate "reversibility" and the response of the Earth system to idealized engineered permanent CO2 removal. Here we present early results of these experiments and also discuss the design and implementation of the next experiments that explore CDR via land use change and ocean alkalinization. In particular we will highlight which components of the simulated climate system exhibit "reversibility", when CO2 increases and then decreases, and the time scales over which this occurs. Many of the trends are similar in different models; however, there is some disagreement in the response of the simulated carbon cycle.

  3. Initial Results from the CHOOZ Long Baseline Reactor Neutrino Oscillation Experiment

    CERN Document Server

    Apollonio, M

    1998-01-01

    Initial results are presented from CHOOZ, a long-baseline reactor-neutrino vacuum-oscillation experiment. Electron antineutrinos were detected by a liquid scintillation calorimeter located at a distance of about 1 km. The detector was constructed in a tunnel protected from cosmic rays by a 300 MWE rock overburden. This massive shielding strongly reduced potentially troublesome backgrounds due to cosmic-ray muons, leading to a background rate of about one event per day, more than an order of magnitude smaller than the observed neutrino signal. From the statistical agreement between detected and expected neutrino event rates, we find (at 90% confidence level) no evidence for neutrino oscillations in the electron antineutrino disappearance mode for the parameter region given approximately by deltam**2 > 0.9 10**(-3) eV**2 for maximum mixing and (sin(2 theta)**2) > 0.18 for large deltam**2.

  4. Focal laser ablation for localized prostate cancer: principles, clinical trials, and our initial experience.

    Science.gov (United States)

    Lee, Ted; Mendhiratta, Neil; Sperling, Dan; Lepor, Herbert

    2014-01-01

    Focal therapy of prostate cancer is an evolving treatment strategy that destroys a predefined region of the prostate gland that harbors clinically significant disease. Although long-term oncologic control has yet to be demonstrated, focal therapy is associated with a marked decrease in treatment-related morbidity. Focal laser ablation is an emerging modality that has several advantages, most notably real-time magnetic resonance imaging (MRI) compatibility. This review presents the principles of laser ablation, the role of multiparametric MRI for delineating the site of significant prostate cancer, a summary of published clinical studies, and our initial experience with 23 patients, criteria for selecting candidates for focal prostate ablation, and speculation regarding future directions.

  5. Initial experiments on the end-point control of a flexible one-link robot

    Science.gov (United States)

    Cannon, R. H., Jr.; Schmitz, E.

    1984-01-01

    The present investigation is concerned with initial experiments regarding a specific unsolved control problem which appeared to be central to advances in the art of robotics. This problem involves the control of a flexible member (one link of a robot system). The position of the end-effector, called the end point or tip, is controlled by measuring that position and using the measurement as a basis for applying control torque to the other end of the flexible member, as for instance, the robot's elbow joint. A description is presented of the features of the first experimental arm which has been made, and an outline is provided of the general strategy for controlling it using its tip sensor and shoulder torquer.

  6. Neonatal extracorporeal membrane oxygenation: Initial experience of Hospital de São João.

    Science.gov (United States)

    Rocha, G; Soares, P; Henriques-Coelho, T; Correia-Pinto, J; Monteiro, J; Guimarães, H; Roncon-Albuquerque, R

    2014-01-01

    The purpose of this series is to report the initial ECMO experience of the Neonatal Intensive Care Unit of Hospital de São João. The first three clinical cases are reported. Case report 1: a 39 weeks gestational age girl with severe lung hypoplasia secondary to a bilateral congenital diaphragmatic hernia. Case report 2: a 39 weeks gestational age girl with a right congenital diaphragmatic hernia and a tracheal stenosis. Case report 3: a 34 weeks gestational age boy, with 61 days of life, with a Bordetella pertussis pneumonia, severe pulmonary hypertension, shock, hyperleukocytosis and seizures. Copyright © 2013 Sociedade Portuguesa de Pneumologia. Published by Elsevier España. All rights reserved.

  7. Imaging Manifestations of Pseudoprogression in Metastatic Melanoma Nodes Injected with Talimogene Laherparepvec: Initial Experience.

    Science.gov (United States)

    Zamora, C; Lopez, M; Cunningham, F; Collichio, F; Castillo, M

    2017-06-01

    Talimogene laherparepvec is an oncolytic virus recently approved for targeted treatment of advanced melanoma. Because of an inflammatory reaction, treated lesions may increase in size and develop infiltrative margins that can be construed as disease progression or extracapsular spread. In this report, we describe our initial experience imaging the response of metastatic nodes injected with talimogene laherparepvec. Six of 12 nodes (50%) showed growth from baseline followed by decreased size, 5 of 12 nodes (42%) showed a downward size trend, and 1 node showed continued increase in size. Seven of 9 nodes (78%) developed infiltrative margins at a median of 79 days, and 6 of 9 (67%) nodes became necrotic at a median of 76 days after injection, all showing decreased size at final follow-up. An increase in the size of nodes injected with talimogene laherparepvec does not necessarily indicate progression. Infiltrative margins are also frequently seen and may be confused with extracapsular disease. © 2017 by American Journal of Neuroradiology.

  8. Establishing and strengthening a medicine and therapeutics committee in a medical college in Nepal: initial experiences.

    Science.gov (United States)

    Shankar, P Ravi; Humagain, Baburam; Piryani, R M; Jha, Nisha; Osti, Bidur

    2009-04-01

    Drug and Therapeutics Committees (DTCs) serve as a forum to bring together various stakeholders to improve drug use. DTCs are a key intervention to promote rational use of medicines. DTCs are however, functioning in only a limited number of hospitals in Nepal. A Medicine and Therapeutics Committee (MTC) was started at KIST Medical College, a new medical school in Lalitpur district, Nepal to promote the rational use of medicines in February 2008. The MTC has members from various departments and the full support of the administration. The MTC has been involved in preparing the hospital medicine list and limiting the number of brands available in the pharmacy. Measures to regulate pharmaceutical promotion have been undertaken. Pharmacovigilance and medication counseling activities have been started. Educational programs for various levels of staff are regularly carried out and drug use in the hospital is periodically monitored. Initial experiences regarding MTC functioning is positive.

  9. Assigning Robust Default Values in Building Performance Simulation Software for Improved Decision-Making in the Initial Stages of Building Design

    Directory of Open Access Journals (Sweden)

    Kyosuke Hiyama

    2015-01-01

    Full Text Available Applying data mining techniques on a database of BIM models could provide valuable insights in key design patterns implicitly present in these BIM models. The architectural designer would then be able to use previous data from existing building projects as default values in building performance simulation software for the early phases of building design. The author has proposed the method to minimize the magnitude of the variation in these default values in subsequent design stages. This approach maintains the accuracy of the simulation results in the initial stages of building design. In this study, a more convincing argument is presented to demonstrate the significance of the new method. The variation in the ideal default values for different building design conditions is assessed first. Next, the influence of each condition on these variations is investigated. The space depth is found to have a large impact on the ideal default value of the window to wall ratio. In addition, the presence or absence of lighting control and natural ventilation has a significant influence on the ideal default value. These effects can be used to identify the types of building conditions that should be considered to determine the ideal default values.

  10. Modified Hybrid Procedure in Hypoplastic Left Heart Syndrome: Initial Experience of a Center in Northeastern Brazil

    Science.gov (United States)

    Faria, Renato Max; Pacheco, Juliana Torres; de Oliveira, Itamar Ribeiro; Vidal, José Madson; Rodrigues Junior, Anilton Bezerra; Costa, Ana Luiza Lafeta; Nina, Vinicius José da Silva; Cascudo, Marcelo Matos

    2017-01-01

    Introduction Although it only corresponds to 2.5% of congenital heart defects, hypoplastic left heart syndrome (HLHS) is responsible for more than 25% of cardiac deaths in the first week of life. Palliative surgery performed after the second week of life is considered an important risk factor in the treatment of HLHS. Objective The aim of this study is to describe the initial experience of a medical center in Northeastern Brazil with a modified off-pump hybrid approach for palliation of HLHS. Methods From November 2012 through November 2015, the medical records of 8 patients with HLHS undergoing hybrid procedure were retrospectively evaluated in a tertiary private hospital in Northeastern Brazil. The modified off-pump hybrid palliation consisted of stenting of the ductus arteriosus guided by fluoroscopy without contrast and banding of the main pulmonary artery branches. Demographic and clinical variables were recorded for descriptive analysis. Results Eight patients were included in this study, of whom 37.5% were female. The median age and weight at the time of the procedure was 2 days (p25% and p75% = 2 and 4.5 days, respectively) and 3150 g (p25% and p75% = 3077.5 g and 3400 g, respectively), respectively. The median length in intensive care unit stay was 6 days (p25% and p75% = 3.5% and 8 days, respectively). There were no in-hospital deaths. Four patients have undergone to the second stage of the surgical treatment of HLHS. Conclusion In this series, the initial experience with the modified off-pump hybrid procedure showed to be safe, allowing a low early mortality rate among children presenting HLHS. PMID:28832800

  11. Modified Hybrid Procedure in Hypoplastic Left Heart Syndrome: Initial Experience of a Center in Northeastern Brazil

    Directory of Open Access Journals (Sweden)

    Renato Max Faria

    Full Text Available Abstract Introduction: Although it only corresponds to 2.5% of congenital heart defects, hypoplastic left heart syndrome (HLHS is responsible for more than 25% of cardiac deaths in the first week of life. Palliative surgery performed after the second week of life is considered an important risk factor in the treatment of HLHS. Objective: The aim of this study is to describe the initial experience of a medical center in Northeastern Brazil with a modified off-pump hybrid approach for palliation of HLHS. Methods: From November 2012 through November 2015, the medical records of 8 patients with HLHS undergoing hybrid procedure were retrospectively evaluated in a tertiary private hospital in Northeastern Brazil. The modified off-pump hybrid palliation consisted of stenting of the ductus arteriosus guided by fluoroscopy without contrast and banding of the main pulmonary artery branches. Demographic and clinical variables were recorded for descriptive analysis. Results: Eight patients were included in this study, of whom 37.5% were female. The median age and weight at the time of the procedure was 2 days (p25% and p75% = 2 and 4.5 days, respectively and 3150 g (p25% and p75% = 3077.5 g and 3400 g, respectively, respectively. The median length in intensive care unit stay was 6 days (p25% and p75% = 3.5% and 8 days, respectively. There were no in-hospital deaths. Four patients have undergone to the second stage of the surgical treatment of HLHS. Conclusion: In this series, the initial experience with the modified off-pump hybrid procedure showed to be safe, allowing a low early mortality rate among children presenting HLHS.

  12. Flight initiation by Ferruginous Hawks depends on disturbance type, experience, and the anthropogenic landscape.

    Science.gov (United States)

    Nordell, Cameron J; Wellicome, Troy I; Bayne, Erin M

    2017-01-01

    The expansion of humans and their related infrastructure is increasing the likelihood that wildlife will interact with humans. When disturbed by humans, animals often change their behaviour, which can result in time and energetic costs to that animal. An animal's decision to change behaviour is likely related to the type of disturbance, the individual's past experience with disturbance, and the landscape in which the disturbance occurs. In southern Alberta and Saskatchewan, we quantified probability of flight initiation from the nest by Ferruginous Hawks (Buteo regalis) during approaches to nests by investigators. We tested if probability of flight was related to different disturbance types, previous experience, and the anthropogenic landscape in which individual Ferruginous Hawks nested. Probability of flight was related to the type of approach by the investigator, the number of previous visits by investigators, and the vehicular traffic around the nest. Approaches by humans on foot resulted in a greater probability of flight than those in a vehicle. Approaches in a vehicle via low traffic volume access roads were related to increased probability of flight relative to other road types. The number of previous investigator approaches to the nest increased the probability of flight. Overall, we found support that Ferruginous Hawks show habituation to vehicles and the positive reinforcement hypotheses as probability of flight was negatively related to an index of traffic activity near the nest. Our work emphasizes that complex, dynamic processes drive the decision to initiate flight from the nest, and contributes to the growing body of work explaining how responses to humans vary within species.

  13. Academics and Learners’ Perceptions on Blended Learning as a Strategic Initiative to Improve Student Learning Experience

    Directory of Open Access Journals (Sweden)

    Ying Adeline Ng Ling

    2017-01-01

    Full Text Available The increasingly tighter shift of socio-economic constraints on higher education sectors in the recent years has called for greater flexibilities in student learning experience both locally and abroad. To this end, we have recently implemented a Blended Learning Initiative in an attempt to provide better learning support and greater flexibility to our students. This initiative is also in line with the University’s aim of having 50% of our learning and teaching delivered on-line by 2020. In this report, we present our findings on academics and learners’ perceptions on the approach which were obtained through surveys. Results showed that blended learning approach was new to the academics and the factors for successful blended learning implementation were identified. Results also showed that learners appreciated the approach as it made learning more accessible and flexible. Furthermore, they also enjoyed the interesting online activities incorporated into their units. In addition, learners were also able to review and pace their own learning. They also perceived that they have the access to the resources and technical ability to cope with online learning materials and activities. Nonetheless, the survey also revealed that learners still prefer to have academics delivering information to them directly rather than a flipped classroom model. In conclusion, findings from this study provide insights that blended learning could be effective to supplement courses offered by the faculty.

  14. Patients' experiences of an initial consultation in oncology: knowing and not knowing.

    Science.gov (United States)

    Furber, Lynn; Bonas, Sheila; Murtagh, Ged; Thomas, Anne

    2015-05-01

    The aim of this paper was to explore how patients experience an initial oncology consultation. This study was part of a larger mixed methods research project designed to address the issue of improving communication and enhancing patient satisfaction with oncology consultations. Interpretive phenomenological analysis was used to interpret the participants' meanings of their experiences in their initial consultation. It is an idiographic approach that focuses in depth on a small set of cases in order to explore how individuals make sense of a similar experience. This retains the complexity and diversity of experiences. In the larger study, semi-structured interviews were carried out with 36 patients as soon as possible after a consultation in oncology to explore their experiences. Five cases were selected for this study on the basis of homogeneity; they had all undergone some prior investigations of their illness, and this was their first consultation in oncology; they all provided rich accounts relating to how they had experienced the consultation. Patients' experiences of being given their diagnosis differed both between participants and within the same participant. Various defences seemed to be used in order to protect them from fully engaging with the knowledge they were given. Their accounts of what they wished to know in the consultation could be affected by a desire to protect themselves and/or family members from distress and by the practical need to know that may vary over time. The complexity of patients' needs and preferences regarding information means that the doctor's role in communicating that information in a patient-centred way is difficult. The findings are discussed in relation to open awareness theory as to how the emotional context of the consultation process affects information needs. Doctors need strategies to elicit information from patients about their needs from the consultation. This needs to be done at the start of consultations and

  15. Experiences with Formal Engineering: Model-Based Specification, Implementation and Testing of a Software Bus at Neopost

    NARCIS (Netherlands)

    Sijtema, Marten; Stoelinga, Mariëlle Ida Antoinette; Belinfante, Axel; Marinelli, Lawrence; Salaün, Gwen; Schätz, Bernhard

    We report on the actual industrial use of formal methods during the development of a software bus. At Neopost Inc., we developed the server component of a software bus, called the XBus, using formal methods during the design, validation and testing phase: We modeled our design of the XBus in the

  16. Experiences with formal engineering: model-based specification, implementation and testing of a software bus at Neopost

    NARCIS (Netherlands)

    Sijtema, M.; Salaün, G.; Schätz, B.; Belinfante, Axel; Stoelinga, Mariëlle Ida Antoinette; Marinelli, L.

    2014-01-01

    We report on the actual industrial use of formal methods during the development of a software bus. During an internship at Neopost Inc., of 14 weeks, we developed the server component of a software bus, called the XBus, using formal methods during the design, validation and testing phase: we modeled

  17. Initial experience with the Ventana fenestrated system for endovascular repair of juxtarenal and pararenal aortic aneurysms.

    Science.gov (United States)

    Holden, Andrew; Mertens, Renato; Hill, Andrew; Mariné, Leopoldo; Clair, Daniel G

    2013-05-01

    time to hospital discharge was 3.3 days (range, 2-9 days). In follow-up to 6 months and 1 year, no rupture, conversion to open repair, migration, type I/III endoleak, or renal loss/infarcts were observed. Two late nonaneurysm-related deaths have occurred. One secondary procedure for iliac limb kinking/occlusion and one secondary procedure for renal artery stenosis have been performed. Early experience supports procedural and initial postprocedural safety and demonstrates proof of concept for the off-the-shelf Ventana fenestrated system for the endovascular repair of JAAs and PAAs in selected patients. Continued follow-up and expanded multicenter clinical experience is warranted. Copyright © 2013 Society for Vascular Surgery. All rights reserved.

  18. Initial experience with the new da Vinci single-port robot-assisted platform.

    Science.gov (United States)

    Ballestero Diego, R; Zubillaga Guerrero, S; Truan Cacho, D; Carrion Ballardo, C; Velilla Diez, G; Calleja Hermosa, P; Gutiérrez Baños, J L

    2017-06-01

    To describe our experience in the first cases of urological surgeries performed with the da Vinci single-port robot-assisted platform. We performed 5 single-port robot-assisted surgeries (R-LESS) between May and October 2014. We performed 3 ureteral reimplant surgeries, one ureteropyeloplasty in an inverted kidney and 1 partial nephrectomy. The perioperative and postoperative results were collected, as well as a report of the complications according to the Clavien classification system. Of the 5 procedures, 4 were performed completely by LESS, while 1 procedure was reconverted to multiport robot-assisted surgery. There were no intraoperative complications. We observed perioperative complications in 4 patients, all of which were grade 1 or 2. The mean surgical time was 262minutes (range, 230-300). In our initial experience with the da Vinci device, R-LESS surgery was feasible and safe. There are still a number of limitations in its use, which require new and improved R-LESS platforms. Copyright © 2016 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  19. "Minimally invasive video-assisted thyroidectomy. Initial experience in a general surgery department".

    Science.gov (United States)

    Dobrinja, Chiara; Trevisan, Giuliano; Liguori, Gennaro

    2009-03-01

    The aim of this study is to analyze our preliminary results from minimally invasive video-assisted thyroidectomy (MIVAT) and demonstrate the feasibility of MIVAT also in non-referral centers. We report our initial experience based on a series of 47 patients selected for MIVAT at General Surgery Department of University of Trieste during a period from May 2005 to February 2007. The eligibility criteria were rigorously observed. Age, goiter volume, major diameter of the dominant nodule, operative times, pathologic findings, postoperative pain, length of hospital stay, cosmetic results, and complications were retrospectively analyzed. Thyroid lobectomy was successfully accomplished in 33 cases, total thyroidectomy in 14. Conversion to standard cervicotomy was required in three patients (6%). Mean operative time of lobectomy was 82.6 min and 118.7 for total thyroidectomy. Postoperative complications included 11 (23.4%) transient hypocalcemias, 2 (4.2%) hematomas, and 2 (4.2%) temporary laryngeal nerve palsies. None-recurrent nerve palsies was observed. The cosmetic result was excellent in most cases. Our experience demonstrates that MIVAT, after adequate training, is feasible and safe, with results comparable to conventional thyroidectomy, also in a General Surgery Department, from a dedicated team, with a sufficient and specific activity volume.

  20. Student Experiences: the 2013 Cascadia Initiative Expedition Team's Apply to Sail Program

    Science.gov (United States)

    Mejia, H.; Hooft, E. E.; Fattaruso, L.

    2013-12-01

    During the summer of 2013, the Cascadia Initiative Expedition Team led six oceanographic expeditions to recover and redeploy ocean bottom seismometers (OBSs) across the Cascadia subduction zone and Juan de Fuca plate. The Cascadia Initiative (CI) is an onshore/offshore seismic and geodetic experiment to study questions ranging from megathrust earthquakes to volcanic arc structure to the formation, deformation and hydration of the Juan de Fuca and Gorda plates with the overarching goal of understanding the entire subduction zone system. The Cascadia Initiative Expedition Team is a team of scientists charged with leading the oceanographic expeditions to deploy and recover CI OBSs and developing the associated Education and Outreach effort. Students and early career scientists were encouraged to apply to join the cruises via the Cascadia Initiative Expedition Team's Apply to Sail Program. The goal of this call for open participation was to help expand the user base of OBS data by providing opportunities for students and scientists to directly experience at-sea acquisition of OBS data. Participants were required to have a strong interest in learning field techniques, be willing to work long hours at sea assisting in OBS deployment, recovery and preliminary data processing and have an interest in working with the data collected. In total, there were 51 applicants to the Apply to Sail Program from the US and 4 other countries; 21 graduate students as well as a few undergraduate students, postdocs and young scientists from the US and Canada were chosen to join the crew. The cruises lasted from 6 to 14 days in length. OBS retrievals comprised the three first legs, of which the first two were aboard the Research Vessel Oceanus. During each of the retrievals, multiple acoustic signals were sent while the vessel completed a semi-circle around the OBS to accurately determine its position, a final signal was sent to drop the seismometer's anchor, and finally the ship and crew

  1. [Evaluation of the influence of humidity and temperature on the drug stability by initial average rate experiment].

    Science.gov (United States)

    He, Ning; Sun, Hechun; Dai, Miaomiao

    2014-05-01

    To evaluate the influence of temperature and humidity on the drug stability by initial average rate experiment, and to obtained the kinetic parameters. The effect of concentration error, drug degradation extent, humidity and temperature numbers, humidity and temperature range, and average humidity and temperature on the accuracy and precision of kinetic parameters in the initial average rate experiment was explored. The stability of vitamin C, as a solid state model, was investigated by an initial average rate experiment. Under the same experimental conditions, the kinetic parameters obtained from this proposed method were comparable to those from classical isothermal experiment at constant humidity. The estimates were more accurate and precise by controlling the extent of drug degradation, changing humidity and temperature range, or by setting the average temperature closer to room temperature. Compared with isothermal experiments at constant humidity, our proposed method saves time, labor, and materials.

  2. User Experience of Interactive Assistive Courseware for Low Vision Learners (AC4LV: Initial Round

    Directory of Open Access Journals (Sweden)

    Nurulnadwan Aziz

    2017-08-01

    Full Text Available This study reports an ongoing projects related to the development of interactive digital learning content which specifically designed catering to needs of low vision learners. Reviews from previous literature indicate that interactive digital learning content particularly for low vision learners is highly scarce. It was found that most of the existing interactive digital learning content focuses on the needs of general students, in which most of this courseware means too little to the low vision learners particularly in terms of information accessibility, navigationability, and pleasurability aspects. This study starts the project by designing a conceptual designed model which then validated it through expert review and prototyping method. The prototype is called Assistive Courseware for Low Vision (AC4LV learners. User Centered Design (UCD approach has been utilized throughout the development of AC4LV. The main aim of this study is to achieve the usefulness of the prototype to the intended user. Therefore, to investigate the usefulness of AC4LV, it has to be tested on the targeted subjects. Thus, this study presents the initial round of user experience testing related to the subjects’ behaviors and reactions on AC4LV in effort to make it as one of the effective learning tools specifically for low vision children. It is called as user experience I. In the test,eight subjects with the average age nine to 12 were involved. Subjective feedbacks were obtained through observation and interview. Overall, it was found that each of the elements in AC4LV is useful to the low vision learners. Future works of the study will report on second round of user experience testing as this study has to achieve the saturated data.

  3. Initial Experience Using a High-Definition 3-Dimensional Exoscope System for Microneurosurgery.

    Science.gov (United States)

    Sack, Jayson; Steinberg, Jeffrey A; Rennert, Robert C; Hatefi, Dustin; Pannell, Jeffrey S; Levy, Michael; Khalessi, Alexander A

    2017-06-29

    The operative microscope and endoscope have significantly advanced modern neurosurgery. These devices are nonetheless limited by high costs and suboptimal optics, ergonomics, and maneuverability. A recently developed extracorporeal telescope ("exoscope") operative system combines characteristics from both the operative microscope and endoscope and provides an affordable, portable, high-definition operative experience. Widespread use of exoscopes in neurosurgery has previously been limited by a lack of stereopsis with 2-dimensional(2-D) monitors. To assess the surgical potential of a novel, 3-D, high-definition (4K-HD) exoscope system. Assess dissection time and visualization of critical structures in a series of human cadaveric cranial neurosurgical approaches with the 3-D 4K-HD exoscope as compared to a standard operating microscope. Dissection times and visualization of critical structures was comparable with the 3-D 4K-HD exoscope and a standard operating microscope. The low-profile exoscope nonetheless allowed for larger operative corridors, enhanced instrument maneuverability, and less obstruction in passing instrumentation. The large monitor also resulted in an immersive surgical experience, and gave multiple team members the same high-quality view as the primary operator. Finally, the exoscope possessed a more ergonomically favorable setup as compared to the traditional microscope, allowing the surgeon to be in a neutral position despite the operative angle. The novel 3-D 4K-HD exoscope system possesses favorable optics, ergonomics, and maneuverability as compared to the traditional operating microscope, with the exoscope's shared surgical view possessing obvious educational and workflow advantages. Further clinical trials are justified to validate this initial cadaveric experience.

  4. Agent Building Software

    Science.gov (United States)

    2000-01-01

    AgentBuilder is a software component developed under an SBIR contract between Reticular Systems, Inc., and Goddard Space Flight Center. AgentBuilder allows software developers without experience in intelligent agent technologies to easily build software applications using intelligent agents. Agents are components of software that will perform tasks automatically, with no intervention or command from a user. AgentBuilder reduces the time and cost of developing agent systems and provides a simple mechanism for implementing high-performance agent systems.

  5. The Workplace Experiences of Beginning Teachers in Three Countries: A Message for Initial Teacher Education from the Field

    Science.gov (United States)

    du Plessis, Anna Elizabeth; Sunde, Eva

    2017-01-01

    Previous research indicates that beginning teachers are not fully prepared for what awaits them in the workforce. This study highlights the value of partnerships among higher education providers, schools and employers and links the experiences of beginning teachers to initial teacher education (ITE). Real-life experiences from the field provide…

  6. Single Institution Early Experience with the Bundled Payments for Care Improvement Initiative.

    Science.gov (United States)

    Iorio, Richard; Bosco, Joseph; Slover, James; Sayeed, Yousuf; Zuckerman, Joseph D

    2017-01-04

    infrastructural changes, although changes may be implemented more thoroughly once initiated. Herein, we discuss our early total joint arthroplasty BPCI experience at our tertiary-care academic medical center.

  7. Heidelberg Ion Therapy Center (HIT): Initial clinical experience in the first 80 patients

    Energy Technology Data Exchange (ETDEWEB)

    Combs, Stephanie E. (Univ. Hospital of Heidelberg, Dept. of Radiation Oncology, Heidelberg (Germany)), E-mail: Stephanie.Combs@med.uni-heidelberg.de; Ellerbrock, Malte; Haberer, Thomas (Heidelberger Ionenstrahl Therapiezentrum (HIT), Im Neuenheimer Feld 450, 69120 Heidelberg (Germany)) (and others)

    2010-10-15

    The Heidelberg Ion Therapy Center (HIT) started clinical operation in November 2009. In this report we present the first 80 patients treated with proton and carbon ion radiotherapy and describe patient selection, treatment planning and daily treatment for different indications. Patients and methods. Between November 15, 2009 and April 15, 2010, 80 patients were treated at the Heidelberg Ion Therapy Center (HIT) with carbon ion and proton radiotherapy. Main treated indications consisted of skull base chordoma (n = 9) and chondrosarcoma (n = 18), malignant salivary gland tumors (n=29), chordomas of the sacrum (n = 5), low grade glioma (n=3), primary and recurrent malignant astrocytoma and glioblastoma (n=7) and well as osteosarcoma (n = 3). Of these patients, four pediatric patients aged under 18 years were treated. Results. All patients were treated using the intensity-modulated rasterscanning technique. Seventy-six patients were treated with carbon ions (95%), and four patients were treated with protons. In all patients x-ray imaging was performed prior to each fraction. Treatment concepts were based on the initial experiences with carbon ion therapy at the Gesellschaft fuer Schwerionenforschung (GSI) including carbon-only treatments and carbon-boost treatments with photon-IMRT. The average time per fraction in the treatment room per patient was 29 minutes; for irradiation only, the mean time including all patients was 16 minutes. Position verification was performed prior to every treatment fraction with orthogonal x-ray imaging. Conclusion. Particle therapy could be included successfully into the clinical routine at the Dept. of Radiation Oncology in Heidelberg. Numerous clinical trials will subsequently be initiated to precisely define the role of proton and carbon ion radiotherapy in radiation oncology.

  8. [LMA CTrach: initial experiences in patients with difficult-to-manage airways].

    Science.gov (United States)

    Timmermann, A; Russo, S; Natge, U; Heuer, J; Graf, B M

    2006-05-01

    The Intubating LMA was designed to facilitate blind intubation and to provide ventilation between two intubation attempts. However, blind intubation can be associated with a risk of oesophageal penetration, therefore, a flexible bronchoscope is frequently used to assist tracheal intubation. This leads to increased burdens on materials and personal resources and prolongs intubation times. Hence the LMA CTrach laryngeal mask airway (CTrach) was developed with an integrated fibreoptic system which can be connected to a monitor for visualisation of the larynx during intubation. We detail the initial experience gained with the practical handling of the CTrach and the application in 10 patients with difficult-to-manage airways. Laryngeal views were graduated in a CTrach-specific classification from grade I (clear view of the arytenoids, glottis and epiglottis) to grade IV (no part of the larynx can be identified). Adjusting manoeuvres were defined to improve the view of laryngeal structures. All patients could be successfully ventilated with the CTrach. Ventilation quality was rated adequate in nine and possible in one patient. The initial distribution of the laryngeal view between grades I-IV was 1/2/1/6 and after adjusting manoeuvres to improve the laryngeal view the grade distribution was 3/5/0/2. Intubation through the CTrach was successful in all patients, nine at first and one at the second attempt. In this small sample of patients with difficult-to-manage airways, the CTrach yielded high success rates for both ventilation and tracheal intubation. Adjusting manoeuvres can improve the laryngeal view further.

  9. Software Engineering Program: Software Process Improvement Guidebook

    Science.gov (United States)

    1996-01-01

    The purpose of this document is to provide experience-based guidance in implementing a software process improvement program in any NASA software development or maintenance community. This guidebook details how to define, operate, and implement a working software process improvement program. It describes the concept of the software process improvement program and its basic organizational components. It then describes the structure, organization, and operation of the software process improvement program, illustrating all these concepts with specific NASA examples. The information presented in the document is derived from the experiences of several NASA software organizations, including the SEL, the SEAL, and the SORCE. Their experiences reflect many of the elements of software process improvement within NASA. This guidebook presents lessons learned in a form usable by anyone considering establishing a software process improvement program within his or her own environment. This guidebook attempts to balance general and detailed information. It provides material general enough to be usable by NASA organizations whose characteristics do not directly match those of the sources of the information and models presented herein. It also keeps the ideas sufficiently close to the sources of the practical experiences that have generated the models and information.

  10. Funding Research Software Development

    Science.gov (United States)

    Momcheva, Ivelina G.

    2017-01-01

    Astronomical software is used by each and every member of our scientific community. Purpose-build software is becoming ever more critical as we enter the regime of large datasets and simulations of increasing complexity. However, financial investments in building, maintaining and renovating the software infrastructure have been uneven. In this talk I will summarize past and current funding sources for astronomical software development, discuss other models of funding and introduce a new initiative for supporting community software at STScI. The purpose of this talk is to prompt discussion about how we allocate resources to this vital infrastructure.

  11. The Year-Two Experiment: Exploring Teachers' Experiences of a 1:1 Technology Initiative

    Science.gov (United States)

    Uy, Jan Michael

    2017-01-01

    This study examined the impact of 1:1 device initiatives in U.S. education K-12 school districts. Specifically, the problem addressed in this research was that studies of the second year of 1:1 technology programs in K-12 school districts had documented challenges among teachers with this change initiative leading to discontent and even…

  12. Robotic NOTES (Natural Orifice Translumenal Endoscopic Surgery) in reconstructive urology: initial laboratory experience.

    Science.gov (United States)

    Haber, Georges-Pascal; Crouzet, Sebastien; Kamoi, Kazumi; Berger, Andre; Aron, Monish; Goel, Raj; Canes, David; Desai, Mihir; Gill, Inderbir S; Kaouk, Jihad H

    2008-06-01

    To present an initial experience with robotic natural orifice translumenal surgery (R-NOTES) in reconstructive urology using the da Vinci surgical system. In 10 female farm pigs (mean weight, 34.5 kg), 10 pyeloplasties (right 5, left 5), 10 partial nephrectomies (right 5, left 5), and 10 radical nephrectomies (right 5, left 5) were performed. The robot telescope and the first robotic arm were placed through a single 2-cm umbilical incision, and the second robotic arm was placed through the vagina. All 30 R-NOTES procedures were performed successfully without any addition of laparoscopic port or open conversion. Mean length of the umbilical incision was 2.6 cm. Mean operative time was 154 minutes, and mean estimated total blood loss was 72 mL. Mean warm ischemia time in the partial nephrectomy group was 25.4 minutes. There were no intraoperative complications. There were no robotic system failures during the entire experiment. We did not find any significant difference when comparing right-side and left-side procedures. When analyzing the learning curve, only robot preparation time reached a statistically significant inverse correlation with increasing number of cases (r = -0.72, P = .018). Robotic NOTES pyeloplasty, partial nephrectomy, and radical nephrectomy are feasible and safe in the porcine model. This approach has the potential for a less morbid and scarless outcome. Intracorporeal suturing is significantly enhanced using the robot, especially through the challenging translumenal natural orifice approach. Further development of robots adaptive to NOTES would boost efforts toward clinical NOTES applications.

  13. Robot-assisted intracorporeal ileal conduit: Marionette technique and initial experience at Roswell Park Cancer Institute.

    Science.gov (United States)

    Guru, Khurshid; Seixas-Mikelus, Stéfanie A; Hussain, Abid; Blumenfeld, Aaron J; Nyquist, John; Chandrasekhar, Rameela; Wilding, Gregory E

    2010-10-01

    To present our technique and initial experience with patients who underwent robot-assisted intracorporeal creation of ileal conduit and to compare them with patients who underwent extracorporeal ileal diversion after robot-assisted radical cystectomy. Twenty-six patients diagnosed with invasive transitional cell carcinoma of the bladder underwent a robot-assisted radical cystectomy with bilateral extended pelvic lymphadenectomy with ileal conduit diversion. Total intracorporeal ileal conduit creation was performed in the last 13 patients. Operative data and short-term outcomes between the 2 groups were assessed. The novel surgical technique for intracorporeal ileal conduit will be presented. The intracorporeal group (IC) included 2 female and 11 male patients (mean age 71 years). The extracorporeal group (EC) included 4 female and 9 male patients (mean age 66 years). No significant differences were noted between the groups in terms of patient age, BMI, sex, prior surgery, or pathologic stage. Overall operative time and intraoperative complications were similar. No significant differences were noted between the 2 groups in terms of diversion time or estimated blood loss. There were 4 complications recorded in IC patients, including nonspecific colitis, small bowel obstruction requiring exploratory laparotomy with lysis of adhesions, a urine leak that eventually resolved but required a temporary nephrostomy tube, and a fever of unknown origin that resolved without intervention. Robot-assisted intracorporeal ileal conduit can be accomplished safely with acceptable operative times even during early experience. Larger series with favorable results will be required to add this new paradigm to minimally invasive surgery for bladder cancer. Copyright © 2010 Elsevier Inc. All rights reserved.

  14. The influence of previous robotic experience in the initial learning curve of laparoscopic radical prostatectomy

    Directory of Open Access Journals (Sweden)

    José Anastácio Dias Neto

    Full Text Available ABSTRACT Introduction: This study analyzed the impact of the experience with Robotic-Assisted Laparoscopic Prostatectomy (RALP on the initial experience with Laparoscopic Radical Prostatectomy (LRP by examining perioperative results and early outcomes of 110 patients. LRPs were performed by two ro-botic fellowship trained surgeons with daily practice in RALP. Patients and Methods: 110 LRP were performed to treat aleatory selected patients. The patients were divided into 4 groups for prospective analyses. A transperitoneal approach that simulates the RALP technique was used. Results: The median operative time was 163 minutes (110-240, and this time significantly decreased through case 40, when the time plateaued (p=0.0007. The median blood loss was 250mL. No patients required blood transfusion. There were no life-threatening complications or deaths. Minor complications were uniformly distributed along the series (P=0.6401. The overall positive surgical margins (PSM rate was 28.2% (20% in pT2 and 43.6% in pT3. PSM was in the prostate apex in 61.3% of cases. At the 12-month follow-up, 88% of men were continent (0-1 pad. Conclusions: The present study shows that there are multiple learning curves for LRP. The shallowest learning curve was seen for the operative time. Surgeons transitioning between the RALP and LRP techniques were considered competent based on the low perioperative complication rate, absence of major complications, and lack of blood transfusions. This study shows that a learning curve still exists and that there are factors that must be considered by surgeons transitioning between the two techniques.

  15. Neonatal extracorporeal membrane oxygenation: Initial experience of Hospital de São João

    Directory of Open Access Journals (Sweden)

    G. Rocha

    2014-11-01

    Full Text Available The purpose of this series is to report the initial ECMO experience of the Neonatal Intensive Care Unit of Hospital de São João. The first three clinical cases are reported. Case report 1: a 39 weeks gestational age girl with severe lung hypoplasia secondary to a bilateral congenital diaphragmatic hernia. Case report 2: a 39 weeks gestational age girl with a right congenital diaphragmatic hernia and a tracheal stenosis. Case report 3: a 34 weeks gestational age boy, with 61 days of life, with a Bordetella pertussis pneumonia, severe pulmonary hypertension, shock, hyperleukocytosis and seizures. Resumo: O objetivo desta série é apresentar a experiência inicial da Unidade de Cuidados Intensivos Neonatais do Hospital de São João com ECMO no recém-nascido. São apresentados os 3 primeiros casos. Caso 1: recém-nascido de 39 semanas de idade gestacional, com hipoplasia pulmonar severa secundária a hérnia diafragmática congénita bilateral. Caso 2: recém-nascido de 39 semanas de idade gestacional, com hérnia diafragmática congénita direita e estenose traqueal. Caso 3: pré-termo de 34 semanas de idade gestacional, sexo masculino, com 61 dias de vida, com pneumonia por Bordetella pertussis, hipertensão pulmonar severa, choque, hiperleucocitose e convulsões. Keywords: Extracorporeal membrane oxygenation, Newborn, Congenital diaphragmatic hernia, Tracheal stenosis, Bordetella pertussis infection, Palavras-chave: Oxigenação por membrana extracorporal, Recém-nascido, Hérnia diafragmática congénita, Estenose traqueal, Infeção por Bordetella pertussis

  16. Initial Results from the STEM Student Experiences Aboard Ships (STEMSEAS) Program

    Science.gov (United States)

    Lewis, J. C.; Cooper, S. K.; Thomson, K.; Rabin, B.; Alberts, J.

    2016-12-01

    The Science Technology Engineering and Math Student Experiences Aboard Ships (STEMSEAS) program was created as a response to NSF's call (through GEOPATHS) for improving undergraduate STEM education and enhancing diversity in the geosciences. It takes advantage of unused berths on UNOLS ships during transits between expeditions. During its 2016 pilot year - which consisted of three transits on three different research vessels in different parts of the country, each with a slightly different focus - the program has gained significant insights into how best to create and structure these opportunities and create impact on individual students. A call for applications resulted in nearly 900 applicants for 30 available spots. Of these applicants, 32% are from minority groups underrepresented in the geosciences (Black, Hispanic, or American Indian) and 20% attend community colleges. The program was able to sail socioeconomically diverse cohorts and include women, veterans, and students with disabilities and from two- and four-year colleges. Twenty-three are underrepresented minorities, 6 attend community colleges, 5 attend an HBCU or tribal college, and many are at HSIs or other MSIs. While longer term impact assessment will have to wait, initial results and 6-month tracking for the first cohort indicate that these kinds of relatively short but intense experiences can indeed achieve significant impacts on students' perception of the geosciences, in their understanding of STEM career opportunities, their desire to work in a geoscience lab setting, and to incorporate geosciences into non-STEM careers. Insights were also gained into the successful makeup of mentor/leader groups, factors to consider in student selection, necessary pre- and post-cruise logistics management, follow-up activities, structure of activities during daily life at sea, increasing student networks and access to mentorships, and leveraging of pre-existing resources and ship-based opportunities

  17. Design and Implementation of a Software for Teaching Health Related Topics to Deaf Students: the First Experience in Iran

    Science.gov (United States)

    Ahmadi, Maryam; Abbasi, Masoomeh; Bahaadinbeigy, Kambiz

    2015-01-01

    Introduction: Deaf are not able to communicate with other community members due to hearing impaired. Providing health care for deaf is more complex because of their communication problems. Multimedia tools can provide multiple tangible concepts (movie, subtitles, and sign language) for the deaf and hard of hearing. In this study, identify the priority health needs of deaf students in primary schools and health education software has been created. Method: Priority health needs and software requirements were identified through interviews with teachers in primary schools in Tehran. After training videos recorded, videos edited and the required software has been created in stages. Results: As a result, health care needs, including: health, dental, ear, nails, and hair care aids, washing hands and face, the corners of the bathroom. Expected Features of the software was including the use of sign language, lip reading, pictures, animations and simple and short subtitles. Discussion: Based on the results of interviews and interest of educators and students to using of educational software for deaf health problems, we can use this software to help Teachers and student’s families to education and promotion the health of deaf students for learn effectively. PMID:26005271

  18. An initial experience with 85 consecutive robotic-assisted rectal dissections: improved operating times and lower costs with experience.

    Science.gov (United States)

    Byrn, John C; Hrabe, Jennifer E; Charlton, Mary E

    2014-11-01

    Data are limited about the robotic platform in rectal dissections, and its use may be perceived as prohibitively expensive or difficult to learn. We report our experience with the initial robotic-assisted rectal dissections performed by a single surgeon, assessing learning curve and cost. Following IRB approval, a retrospective chart review was conducted of the first 85 robotic-assisted rectal dissections performed by a single surgeon between 9/1/2010 and 12/31/2012. Patient demographic, clinicopathologic, procedure, and outcome data were gathered. Cost data were obtained from the University HealthSystem Consortium (UHC) database. The first 43 cases (Time 1) were compared to the next 42 cases (Time 2) using multivariate linear and logistic regression models. Indications for surgery were cancer for 51 patients (60 %), inflammatory bowel disease for 18 (21 %), and rectal prolapse for 16 (19 %). The most common procedures were low anterior resection (n = 25, 29 %) and abdominoperineal resection (n = 21, 25 %). The patient body mass index (BMI) was statistically different between the two patient groups (Time 1, 26.1 kg/m(2) vs. Time 2, 29.4 kg/m(2), p = 0.02). Complication and conversion rates did not differ between the groups. Mean operating time was significantly shorter for Time 2 (267 min vs. 224 min, p = 0.049) and remained significant in multivariate analysis. Though not reaching statistical significance, the mean observed direct hospital cost decreased ($17,349 for Time 1 vs. $13,680 for Time 2, p = 0.2). The observed/expected cost ratio significantly decreased (1.47 for Time 1 vs. 1.05 for Time 2, p = 0.007) but did not remain statistically significant in multivariate analyses. Over the series, we demonstrated a significant improvement in operating times. Though not statistically significant, direct hospital costs trended down over time. Studies of larger patient groups are needed to confirm these findings and to correlate them with procedure volume to better

  19. Initial experience in hybrid PET-MRI for evaluation of refractory focal onset epilepsy.

    Science.gov (United States)

    Shin, Hae W; Jewells, Valerie; Sheikh, Arif; Zhang, Jingwen; Zhu, Hongtu; An, Hongyu; Gao, Wei; Shen, Dinggang; Hadar, Eldad; Lin, Weili

    2015-09-01

    We aim to evaluate the utility/improved accuracy of hybrid PET/MR compared to current practice separate 3T MRI and PET-CT imaging for localization of seizure foci. In a pilot study, twenty-nine patients undergoing epilepsy surgery evaluation were imaged using PET/MR. This subject group had 29 previous clinical 3T MRI as well as 12 PET-CT studies. Prior clinical PET and MR images were read sequentially while the hybrid PET/MR was concurrently read. The median interval between hybrid PET/MR and prior imaging studies was 5 months (range 1-77 months). In 24 patients, there was no change in the read between the clinical exams and hybrid PET/MR while new anatomical or functional lesions were identified by hybrid PET/MR in 5 patients without significant clinical change. Four new anatomical MR lesions were seen with concordant PET findings. The remaining patient revealed a new abnormal PET lesion without an MR abnormality. All new PET/MR lesions were clinically significant with concordant EEG and/or SPECT results as potential epileptic foci. Our initial hybrid PET-MRI experience increased diagnostic yields for detection of potential epileptic lesions. This may be due to the unique advantage of improved co-registration and simultaneous review of both structural and functional data. Copyright © 2015 British Epilepsy Association. Published by Elsevier Ltd. All rights reserved.

  20. Preparing beginning reading teachers: An experimental comparison of initial early literacy field experiences.

    Science.gov (United States)

    Al Otaiba, Stephanie; Lake, Vickie E; Greulich, Luana; Folsom, Jessica S; Guidry, Lisa

    2012-01-01

    This randomized-control trial examined the learning of preservice teachers taking an initial Early Literacy course in an early childhood education program and of the kindergarten or first grade students they tutored in their field experience. Preservice teachers were randomly assigned to one of two tutoring programs: Book Buddies and Tutor Assisted Intensive Learning Strategies (TAILS), which provided identical meaning-focused instruction (shared book reading), but differed in the presentation of code-focused skills. TAILS used explicit, scripted lessons, and the Book Buddies required that code-focused instruction take place during shared book reading. Our research goal was to understand which tutoring program would be most effective in improving knowledge about reading, lead to broad and deep language and preparedness of the novice preservice teachers, and yield the most successful student reading outcomes. Findings indicate that all pre-service teachers demonstrated similar gains in knowledge, but preservice teachers in the TAILS program demonstrated broader and deeper application of knowledge and higher self-ratings of preparedness to teach reading. Students in both conditions made similar comprehension gains, but students tutored with TAILS showed significantly stronger decoding gains.

  1. Initial experience with use of hydrogel microcoils in embolization of pulmonary arteriovenous malformations.

    Science.gov (United States)

    Osuga, Keigo; Kishimoto, Kentaro; Tanaka, Kaishu; Nakamura, Masahisa; Ono, Yusuke; Maeda, Noboru; Higashihara, Hiroki; Nakazawa, Tetsuro; Tomiyama, Noriyuki

    2014-01-01

    The purpose of this study is to describe our initial experience with embolization of pulmonary arteriovenous malformations (PAVMs) using hydrogel microcoils. The technical and radiological outcomes were retrospectively reviewed in seven patients with nine simple-type PAVMs (median feeder size 4 mm, range 3-6 mm) who underwent embolization. Hydrogel microcoils were mainly used, and detachable bare microcoils were combined as needed to occlude the terminal feeding artery just before the sac. Of a total of 43 microcoils, 30 (69.8%) hydrogel microcoils were deployed in eight PAVMs with the median number 3.5 (range 2 to 6) per lesion. All hydrogel microcoils were successfully deployed without microcatheter stuck or malposition. In the remaining one small PAVM, only soft bare microcoils were used, however, resulting in recanalization requiring additional coils in the second session. The venous sac was substantially shrunk in all lesions treated with hydrogel microcoils with the median size reduction rate 95.0% (range 81.8% to 99.0%) during the median follow-up period 10 months (range 6 to 18 months). In conclusion, hydrogel microcoils were safely and effectively applied for occluding PAVMs with relatively small feeders.

  2. Implementing a robotics curriculum at an academic general surgery training program: our initial experience.

    Science.gov (United States)

    Winder, Joshua S; Juza, Ryan M; Sasaki, Jennifer; Rogers, Ann M; Pauli, Eric M; Haluck, Randy S; Estes, Stephanie J; Lyn-Sue, Jerome R

    2016-09-01

    The robotic surgical platform is being utilized by a growing number of hospitals across the country, including academic medical centers. Training programs are tasked with teaching their residents how to utilize this technology. To this end, we have developed and implemented a robotic surgical curriculum, and share our initial experience here. Our curriculum was implemented for all General Surgical residents for the academic year 2014-2015. The curriculum consisted of online training, readings, bedside training, console simulation, participating in ten cases as bedside first assistant, and operating at the console. 20 surgical residents were included. Residents were provided the curriculum and notified the department upon completion. Bedside assistance and operative console training were completed in the operating room through a mix of biliary, foregut, and colorectal cases. During the fiscal years of 2014 and 2015, there were 164 and 263 robot-assisted surgeries performed within the General Surgery Department, respectively. All 20 residents completed the online and bedside instruction portions of the curriculum. Of the 20 residents trained, 13/20 (65 %) sat at the Surgeon console during at least one case. Utilizing this curriculum, we have trained and incorporated residents into robot-assisted cases in an efficient manner. A successful curriculum must be based on didactic learning, reading, bedside training, simulation, and training in the operating room. Each program must examine their caseload and resident class to ensure proper exposure to this platform.

  3. An initial experience with a digital drainage system during the postoperative period of pediatric thoracic surgery

    Directory of Open Access Journals (Sweden)

    Altair da Silva Costa Jr

    Full Text Available ABSTRACT Objective: To report an initial experience with a digital drainage system during the postoperative period of pediatric thoracic surgery. Methods: This was a prospective observational study involving consecutive patients, ≤ 14 years of age, treated at a pediatric thoracic surgery outpatient clinic, for whom pulmonary resection (lobectomy or segmentectomy via muscle-sparing thoracotomy was indicated. The parameters evaluated were air leak (as quantified with the digital system, biosafety, duration of drainage, length of hospital stay, and complications. The digital system was used in 11 children (mean age, 5.9 ± 3.3 years. The mean length of hospital stay was 4.9 ± 2.6 days, the mean duration of drainage was 2.5 ± 0.7 days, and the mean drainage volume was 270.4 ± 166.7 mL. The mean maximum air leak flow was 92.78 ± 95.83 mL/min (range, 18-338 mL/min. Two patients developed postoperative complications (atelectasis and pneumonia, respectively. The use of this digital system facilitated the decision-making process during the postoperative period, reducing the risk of errors in the interpretation and management of air leaks.

  4. Catheter closure of patent foramen ovale in patients with cryptogenic cerebrovascular accidents: initial experiences in Japan.

    Science.gov (United States)

    Kijima, Yasufumi; Akagi, Teiji; Nakagawa, Koji; Taniguchi, Manabu; Ueoka, Akira; Deguchi, Kentaro; Toh, Norihisa; Oe, Hiroki; Kusano, Kengo; Sano, Shunji; Ito, Hiroshi

    2014-01-01

    Although numerous studies have shown an association between a patent foramen ovale (PFO) and cryptogenic cerebrovascular accidents (CVA), there has been no definitive control study that demonstrated the benefit of percutaneous device closure of a PFO compared to medical therapy in patients with CVA. Additionally, few clinical data exist for Japanese patients in this field. We demonstrate the initial experiences in catheter closure of a PFO as secondary prevention of CVA in Japan. Catheter closure of a PFO was attempted in 7 patients who were diagnosed with cryptogenic CVA. Mean age at the procedure was 54 ± 19 years. The presence of spontaneous interatrial right-to-left shunts was demonstrated by transesophageal contrast echocardiography without Valsalva maneuver in all of the patients. Amplatzer Cribriform device (n = 4) or Amplatzer PFO Occluder (n = 3) was used for the procedure and was successfully deployed. Device-related complications were not observed at the time of the procedure or during the follow-up period (mean period of 16 ± 9 months). Catheter closure of a PFO could be safely performed with Amplatzer Cribriform or Amplatzer PFO Occluder. This procedure may contribute to prevention of recurrent cryptogenic CVA in Japanese patients.

  5. Single-port laparoscopic approach of the left liver: initial experience.

    Science.gov (United States)

    Camps Lasa, Judith; Cugat Andorrà, Esteban; Herrero Fonollosa, Eric; García Domingo, María Isabel; Sánchez Martínez, Raquel; Vargas Pierola, Harold; Rodríguez Campos, Aurora

    2014-11-01

    New technological advances have enabled the development of single-port laparoscopic surgery. This approach began with cholecystectomy and subsequently with other abdominal surgeries. However, few publications on laparoscopic liver surgery have described the use of complete single-port access. We present our initial experience of a single-port laparoscopic hepatectomy. Between May 2012 and December 2013, 5 single-port laparoscopic hepatectomies were performed: one for benign disease and four for colorectal liver metastases. The lesions were approached through a 3-5 cm right supraumbilical incision using a single-port access device. All the lesions were located in hepatic segments II or III. Four left lateral sectorectomies and one left hepatectomy were performed. Median operative time was 135 min. No cases were converted to conventional laparoscopic or open surgery. The oral intake began at 18 h. There were no postoperative complications and no patients required blood transfusion. The median hospital stay was 3 days. The degree of satisfaction was very good in 4 cases and good in one. Patients resumed their normal daily activities at 8 days. Single-port laparoscopic hepatectomy is safe and feasible in selected cases and may reduce surgical aggression and offer better cosmetic results. Comparative studies are needed to determine the real advantages of this approach. Copyright © 2014 AEC. Published by Elsevier Espana. All rights reserved.

  6. MR imaging-guided cryoablation of metastatic brain tumours: initial experience in six patients

    Energy Technology Data Exchange (ETDEWEB)

    Li, Chengli; Wu, Lebin; Song, Jiqing; Liu, Ming; Lv, Yubo [Shandong University, Shandong Provincial Medical Imaging Research Institute, Jinan, Shandong (China); Sequeiros, Roberto Blanco [Shandong University, Shandong Provincial Medical Imaging Research Institute, Jinan, Shandong (China); Oulu University Hospital, Department of Radiology, Oulu (Finland)

    2010-02-15

    The objective was to evaluate the initial experience and safety of magnetic resonance imaging (MRI)-guided transcranial cryoablation in cystic metastatic brain tumours. Seven cystic metastatic brain tumours in six patients were treated with cryoablation. The approval from the local ethics committee and individual patient consent were acquired before the study. Before the procedure the tumours were detected with conventional CT or MRI. The procedure was performed under local anaesthesia and conscious sedation. A 0.23-T open MRI system with optical tracking was used for procedural planning, instrument guidance and procedural monitoring of the ice ball formation. An MR-compatible, argon-based cryoablation system was used. The schedule of follow-up imaging ranged from 12 days to 12 months. Seven treatment sessions were performed. All the cryoprobes were successfully inserted into the target with one pass. All the patients tolerated the procedure well without experiencing any neurological deficits during the treatment phase or during the immediate post-treatment period. One patient died 12 days after cryoablation. MR-guided and monitored metastasis brain tumour cryoablation is technically feasible and may represent an alternative treatment in selected patients. (orig.)

  7. Robotic liver resection: initial experience with three-arm robotic and single-port robotic technique.

    Science.gov (United States)

    Kandil, Emad; Noureldine, Salem I; Saggi, Bob; Buell, Joseph F

    2013-01-01

    Robotic-assisted surgery offers a solution to fundamental limitations of conventional laparoscopic surgery, and its use is gaining wide popularity. However, the application of this technology has yet to be established in hepatic surgery. A retrospective analysis of our prospectively collected liver surgery database was performed. Over a 6-month period, all consecutive patients who underwent robotic-assisted hepatic resection for a liver neoplasm were included. Demographics, operative time, and morbidity encountered were evaluated. A total of 7 robotic-assisted liver resections were performed, including 2 robotic-assisted single-port access liver resections with the da Vinci-Si Surgical System (Intuitive Surgical Sunnyvalle, Calif.) USA. The mean age was 44.6 years (range, 21-68 years); there were 5 male and 2 female patients. The mean operative time (± SD) was 61.4 ± 26.7 minutes; the mean operative console time (± SD) was 38.2 ± 23 minutes. No conversions were required. The mean blood loss was 100.7 mL (range, 10-200 mL). The mean hospital stay (± SD) was 2 ± 0.4 days. No postoperative morbidity related to the procedure or death was encountered. Our initial experience with robotic liver resection confirms that this technique is both feasible and safe. Robotic-assisted technology appears to improve the precision and ergonomics of single-access surgery while preserving the known benefits of laparoscopic surgery, including cosmesis, minimal morbidity, and faster recovery.

  8. Myocardial delayed-enhancement CT: initial experience in children and young adults

    Energy Technology Data Exchange (ETDEWEB)

    Goo, Hyun Woo [University of Ulsan College of Medicine, Department of Radiology and Research Institute of Radiology, Asan Medical Center, Seoul (Korea, Republic of)

    2017-10-15

    Clinical utility of myocardial delayed enhancement CT has not been reported in children and young adults. To describe initial experience of myocardial delayed enhancement CT regarding image quality, radiation dose and identification of myocardial lesions in children and young adults. Between August 2013 and November 2016, 29 consecutive children and young adults (median age 16 months) with suspected coronary artery or myocardial abnormality underwent arterial- and delayed-phase cardiac CT at our institution. We measured CT densities in normal myocardium, left ventricular cavity, and arterial and delayed hypo-enhancing and delayed hyperenhancing myocardial lesions. We then compared the extent of delayed hyperenhancing lesions with delayed-enhancement MRI or thallium single-photon emission CT. Normal myocardium and left ventricular cavity showed significantly higher CT numbers on arterial-phase CT than on delayed-phase CT (t-test, P<0.0001). Contrast-to-noise ratios of the arterial and delayed hypo-enhancing and delayed hyperenhancing lesions on CT were 26.7, 17.6 and 18.7, respectively. Delayed-phase CT findings were equivalent to those of delayed-enhancement MRI in all cases (7/7) and to those of thallium single-photon emission CT in 70% (7/10). Myocardial delayed-enhancement CT can be added to evaluate myocardial lesions in select children and young adults with suspected coronary artery or myocardial abnormality. (orig.)

  9. Intraoperative imaging during Mohs surgery with reflectance confocal microscopy: initial clinical experience

    Science.gov (United States)

    Flores, Eileen S.; Cordova, Miguel; Kose, Kivanc; Phillips, William; Rossi, Anthony; Nehal, Kishwer; Rajadhyaksha, Milind

    2015-06-01

    Mohs surgery for the removal of nonmelanoma skin cancers (NMSCs) is performed in stages, while being guided by the examination for residual tumor with frozen pathology. However, preparation of frozen pathology at each stage is time consuming and labor intensive. Real-time intraoperative reflectance confocal microscopy (RCM), combined with video mosaicking, may enable rapid detection of residual tumor directly in the surgical wounds on patients. We report our initial experience on 25 patients, using aluminum chloride for nuclear contrast. Imaging was performed in quadrants in the wound to simulate the Mohs surgeon's examination of pathology. Images and videos of the epidermal and dermal margins were found to be of clinically acceptable quality. Bright nuclear morphology was identified at the epidermal margin and detectable in residual NMSC tumors. The presence of residual tumor and normal skin features could be detected in the peripheral and deep dermal margins. Intraoperative RCM imaging may enable detection of residual tumor directly on patients during Mohs surgery, and may serve as an adjunct for frozen pathology. Ultimately, for routine clinical utility, a stronger tumor-to-dermis contrast may be necessary, and also a smaller microscope with an automated approach for imaging in the entire wound in a rapid and controlled manner.

  10. Some challenges facing software engineers developing software for scientists

    OpenAIRE

    Segal, Judith

    2009-01-01

    In this paper, the author discusses two types of challenges facing software engineers as they develop software for scientists. The first type is those challenges that arise from the experience that scientists might have of developing their own software. From this experience, they internalise a model of software development but may not realise the contextual factors which make such a model successful. They thus have expectations and assumptions which prove challenging to software engineers. Th...

  11. Software preservation

    Directory of Open Access Journals (Sweden)

    Tadej Vodopivec

    2011-01-01

    Full Text Available Comtrade Ltd. covers a wide range of activities related to information and communication technologies; its deliverables include web applications, locally installed programs,system software, drivers, embedded software (used e.g. in medical devices, auto parts,communication switchboards. Also the extensive knowledge and practical experience about digital long-term preservation technologies have been acquired. This wide spectrum of activities puts us in the position to discuss the often overlooked aspect of the digital preservation - preservation of software programs. There are many resources dedicated to digital preservation of digital data, documents and multimedia records,but not so many about how to preserve the functionalities and features of computer programs. Exactly these functionalities - dynamic response to inputs - render the computer programs rich compared to documents or linear multimedia. The article opens the questions on the beginning of the way to the permanent digital preservation. The purpose is to find a way in the right direction, where all relevant aspects will be covered in proper balance. The following questions are asked: why at all to preserve computer programs permanently, who should do this and for whom, when we should think about permanent program preservation, what should be persevered (such as source code, screenshots, documentation, and social context of the program - e.g. media response to it ..., where and how? To illustrate the theoretic concepts given the idea of virtual national museum of electronic banking is also presented.

  12. Rising from failure and learning from success: the role of past experience in radical initiative taking

    NARCIS (Netherlands)

    Deichmann, D.; van den Ende, J..

    2014-01-01

    We investigate how the successes and failures of people who initiate radical ideas influence (a) the inclination to take new personal initiatives and (b) the outcome of those initiatives. Using the data of 1,792 radical ideas suggested by 908 employees in a multinational firm's idea and innovation

  13. Validation and experience of a year with an independent calculation software for VMAT fields; Validacion y experencia de un ano con un software de calculo independiente para campos VMAT

    Energy Technology Data Exchange (ETDEWEB)

    Mata Colodro, F.; Serna Berna, A.; Puchades Puchades, V.; Ramos Amores, D.

    2013-07-01

    It is widely accepted that in the process of quality control prior to any treatment must be a redundant and independent (CRI) calculation of the dose or monitor units obtained by treatment Planner. In the case of 3D (3D CRT) conformed radiotherapy treatments these calculations could even be done manually using basic dosimetric data. However, intensity-modulated fields requires a more complex software. Diamond (PTW) is an application that allows to calculate fields with modulation of intensity and, in particular, in addition to conventional fields, fields VMAT (volumetric modulated arc therapy). In this work the validation and findings presented after one year of clinical experience with VMAT fields. (Author)

  14. Prevalence of Sexual Experience and Initiation of Sexual Intercourse Among Adolescents, Rakai District, Uganda, 1994-2011

    DEFF Research Database (Denmark)

    Santelli, John S; Song, Xiaoyu; Larsen Holden, Inge Kristine

    2015-01-01

    PURPOSE: The purpose of the study was to identify risk factors and time trends for sexual experience and sexual debut in rural Uganda. METHODS: Using population-based, longitudinal data from 15- to 19-year olds in Rakai, Uganda, we examined temporal trends in the prevalence of sexual experience......: Sexual experience was more common among adolescent women than men. The prevalence of sexual experience rose for most age-gender groups after 1994 and then declined after 2002. Factors associated with higher prevalence of sexual experience (without adjustment for other factors) included age, not enrolled...... in school, orphanhood, lower socioeconomic status, and drinking alcohol in the past 30 days; similar factors were associated with initiation of sex. Factors independently associated with initiation of sex included older age, nonenrollment in school (IRR = 1.7 for women and 1.8 for men), alcohol use (IRR = 1...

  15. The experience of initiating injection drug use and its social context: a qualitative systematic review and thematic synthesis.

    Science.gov (United States)

    Guise, Andy; Horyniak, Danielle; Melo, Jason; McNeil, Ryan; Werb, Dan

    2017-12-01

    Understanding the experience of initiating injection drug use and its social contexts is crucial to inform efforts to prevent transitions into this mode of drug consumption and support harm reduction. We reviewed and synthesized existing qualitative scientific literature systematically to identify the socio-structural contexts for, and experiences of, the initiation of injection drug use. We searched six databases (Medline, Embase, PsychINFO, CINAHL, IBSS and SSCI) systematically, along with a manual search, including key journals and subject experts. Peer-reviewed studies were included if they qualitatively explored experiences of or socio-structural contexts for injection drug use initiation. A thematic synthesis approach was used to identify descriptive and analytical themes throughout studies. From 1731 initial results, 41 studies reporting data from 1996 participants were included. We developed eight descriptive themes and two analytical (higher-order) themes. The first analytical theme focused on injecting initiation resulting from a social process enabled and constrained by socio-structural factors: social networks and individual interactions, socialization into drug-using identities and choices enabled and constrained by social context all combine to produce processes of injection initiation. The second analytical theme addressed pathways that explore varying meanings attached to injection initiation and how they link to social context: seeking pleasure, responses to increasing tolerance to drugs, securing belonging and identity and coping with pain and trauma. Qualitative research shows that injection drug use initiation has varying and distinct meanings for individuals involved and is a dynamic process shaped by social and structural factors. Interventions should therefore respond to the socio-structural influences on injecting drug use initiation by seeking to modify the contexts for initiation, rather than solely prioritizing the reduction of individual

  16. The views and experiences of nurses and midwives in the provision and management of provider-initiated HIV testing and counseling: a systematic review of qualitative evidence.

    Science.gov (United States)

    Evans, Catrin; Nalubega, Sylivia; McLuskey, John; Darlington, Nicola; Croston, Michelle; Bath-Hextall, Fiona

    2016-01-15

    Global progress towards HIV prevention and care is contingent upon increasing the number of those aware of their status through HIV testing. Provider-initiated HIV testing and counseling is recommended globally as a strategy to enhance uptake of HIV testing and is primarily conducted by nurses and midwives. Research shows that provider-initiated HIV testing and counseling implementation is sub-optimal. The reasons for this are unclear. The review aimed to explore nurses' and midwives' views and experiences of the provision and management of provider-initiated HIV testing and counseling. All cadres of nurses and midwives were considered, including those who undertake routine HIV testing as part of a diverse role and those who are specifically trained as HIV counselors. Types of phenomenon of interest: The review sought to understand the views and experiences of the provision and management of provider-initiated HIV testing and counseling (including perceptions, opinions, beliefs, practices and strategies related to HIV testing and its implementation in practice). The review included only provider-initiated HIV testing and counseling. It excluded all other models of HIV testing. The review included all countries and all healthcare settings. Types of studies: This review considered all forms of qualitative study design and methodology. Qualitative elements of a mixed method study were included if they were presented separately within the publication. A three-step search strategy was utilized. Eight databases were searched for papers published from 1996 to October 2014, followed by hand searching of reference lists. Only studies published in the English language were considered. Methodological quality was assessed using the Qualitative Assessment and Review Instrument developed by the Joanna Briggs Institute. Qualitative findings were extracted using the Joanna Briggs Institute Qualitative Assessment and Review Instrument. Qualitative research findings were pooled

  17. Infusing Software Engineering Technology into Practice at NASA

    Science.gov (United States)

    Pressburger, Thomas; Feather, Martin S.; Hinchey, Michael; Markosia, Lawrence

    2006-01-01

    We present an ongoing effort of the NASA Software Engineering Initiative to encourage the use of advanced software engineering technology on NASA projects. Technology infusion is in general a difficult process yet this effort seems to have found a modest approach that is successful for some types of technologies. We outline the process and describe the experience of the technology infusions that occurred over a two year period. We also present some lessons from the experiences.

  18. Dynamic sentinel node biopsy for penile cancer: an initial experience in an Irish Hospital.

    Science.gov (United States)

    Lonergan, P E; Nic An Riogh, A; O'Kelly, F; Lundon, D J; O'Sullivan, D; O'Connell, M; Hegarty, P K

    2017-11-01

    The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive radiological investigations are unreliable in excluding micrometastatic disease. Dynamic sentinel node biopsy (DSNB) is a minimally invasive procedure for assessing lymph node involvement. We report our initial experience with DSNB in assessing the status of regional lymph nodes in cN0 penile cancer patients. DSNB was performed in penile cancer patients with at least one cN0 groin. All patients undergoing DSNB at our institution were included. Lymphoscintigraphic images were obtained from all patients, after intradermal, peritumoral injection of a Technetium-99m nanocolloid. The sentinel nodes were defined as the nodes identified on lymphoscintigraphy, which were also radioactive intraoperatively using a gamma probe. In total, 18 groins from 11 patients underwent DSNB. Of these, 11 patients underwent bilateral DSNB and 4 had unilateral DSNB. The mean (range) age of patients at the time of presentation of their primary tumour was 63 (39-78) years. A mean of 1.2 nodes per groin was retrieved. One lymph node was positive in one patient, who subsequently underwent a bilateral inguinal lymph node dissection. Overall, the median (range) follow-up was 12.8 (2.7-31.3) months with no local or regional recurrences. Further cases and longer follow-up will define the accuracy of this technique in the Irish population.

  19. Transperineal prostate biopsy with ECHO-MRI fusion. Biopsee system. Initial experience.

    Science.gov (United States)

    Romero-Selas, E; Cuadros, V; Montáns, J; Sánchez, E; López-Alcorocho, J M; Gómez-Sancha, F

    2016-06-01

    The aim of this study is to present our initial experience with the stereotactic echo-MRI fusion system for diagnosing prostate cancer. Between September 2014 and January 2015, we performed 50 prostate biopsies using the stereotactic echo-MRI fusion system. The 3-Tesla multiparameter MR images were superimposed using this image fusion system on 3D echo images obtained with the Biopsee system for the exact locating of areas suspected of prostate cancer. The lesions were classified using the Prostate Imaging Report and Date System. We assessed a total of 50 patients, with a mean age of 63 years (range, 45-79), a mean prostate-specific antigen level of 8 ng/mL (range, 1.9-20) and a mean prostate volume of 52mL (range, 12-118). Prostate cancer was diagnosed in 69% of the patients and intraepithelial neoplasia in 6%. The results of the biopsy were negative for 24% of the patients. The results of the biopsy and MRI were in agreement for 62% of the patients; however, 46% also had a tumour outside of the suspicious lesion. We diagnosed 46% anterior tumours and 33% apical tumours. One patient had a haematuria, another had a haematoma and a third had acute urine retention. Multiparametric prostatic MRI helps identify prostate lesions suggestive of cancer. The Biopsee echo-MRI fusion system provides for guided biopsy and increases the diagnostic performance, reducing the false negatives of classical biopsies and increasing the diagnosis of anterior tumours. Transperineal access minimises the risk of prostatic infection and sepsis. Copyright © 2015 AEU. Publicado por Elsevier España, S.L.U. All rights reserved.

  20. Transumbilical laparo-endoscopic single site surgery for adrenal cortical adenoma inducing primary aldosteronism: initial experience

    Directory of Open Access Journals (Sweden)

    Kikuchi Eiji

    2011-09-01

    Full Text Available Abstract Background We have started using laparo-endoscopic single-site surgery (LESS in urologic surgery, although its use has not gained momentum due to its level of difficulty. We here report our initial experience with transumbilical LESS for adrenal cortical adenoma by using a single port with a multichannel cannula (SILS port and bent laparoscopic instrumentation. Findings A multichannel port (SILS port, bent laparoscopic instrument (Roticulator Endo Mini-Shears and Opti4 laparoscopic electrodes were used in all cases. The intraperitoneal space was approached through the umbilicus. The SILS port was placed through a 2 cm incision at the inner edge of the umbilicus. A 5 mm flexible laparoscope was introduced to keep the laparoscope outside, and surgical specimens were extracted using an Endocatch bag. In addition, as a case control study, we compared perioperative data of LESS adrenalectomy (LESS-A with that of conventional laparoscopic adrenalectomy (LA. We performed transumbilical LESS-A for adrenal cortical adenoma in 12 cases, beginning in December, 2009. All procedures were successfully completed, with only one incision through the umbilicus, and without conversion to a standard laparoscopic approach. Mean operative time for LESS-A was 121.2 ± 7.8 min, which was slightly longer than LA (110.2 ± 7.3 min. For right adrenal tumors, we used a miniport (2 mm port in addition to a SILS port, and were able to successfully perform adrenalectomy "with no visible scaring". Tumor laterality and patient BMI did not affect surgical morbidity in these procedures. Moreover, there was no significant difference between LESS-A and LA in blood loss, analgesic requirement, hospital stay, and scar satisfaction. Conclusions The transumbilical approach in LESS for adrenalectomy is safe and feasible and also improves cosmetic outcome compared with standard laparoscopic procedures. Improvements in surgical devices may aid the further development of this

  1. Thermal-Hydraulic Performance of the TREAT Multi-SERTTA for Reactivity Initiated Accident Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Colby B.; Folsom, Charles P.; Davis, Cliff B.; Woolstenhulme, Nicolas E.; Bess, John D.; O' Brien, Robert C.; Ban, Heng; Wachs, Daniel M.

    2016-08-01

    Experimental testing in the Multi-Static Environment Rodlet Transient Test Apparatus (SERTTA) will lead the rebirth of transient fuel testing in the United States as part of the Accident Tolerant Fuels (ATF) progam. The Multi-SERTTA is comprised of four isolated pressurized environments capable of a wide variety of working fluids and thermal conditions. Ultimately, the TREAT reactor as well as the Multi-SERTTA test vehicle serve the purpose of providing desired thermal-hydraulic boundary conditions to the test specimen. The initial ATF testing in TREAT will focus on reactivity insertion accident (RIA) events using both gas and water environments including typical PWR operating pressures and temperatures. For the water test environment, a test configuration is envisioned using the expansion tank as part of the gas-filled expansion volume seen by the test to provide additional pressure relief. The heat transfer conditions during the high energy power pulses of RIA events remains a subject of large uncertainty and great importance for fuel performance predictions. To support transient experiments, the Multi-SERTTA vehicle has been modeled using RELAP5 with a baseline test specimen composed of UO2 fuel in zircaloy cladding. The modeling results show the influence of the designs of the specimen, vehicle, and transient power pulses. The primary purpose of this work is to provide input and boundary conditions to fuel performance code BISON. Therefore, studies of parameters having influence on specimen performance during RIA transients are presented including cladding oxidation, power pulse magnitude and width, cladding-to-coolant heat fluxes, fuel-to-cladding gap, transient boiling effects (modified CHF values), etc. The results show the great flexibility and capacity of the TREAT Multi-SERTTA test vehicle to provide testing under a wide range of prototypic thermal-hydraulic conditions as never done before.

  2. Single-incision laparoscopic colectomy without using special articulating instruments: an initial experience

    Directory of Open Access Journals (Sweden)

    Trakarnsanga Atthaphorn

    2011-12-01

    Full Text Available Abstract Background Single-incision laparoscopic colectomy (SILC was introduced as a novel minimally invasive technique. The benefits of this technique include reducing number of the incision and cosmetic improvement. Unlike the conventional laparoscopic colectomy, majority of previously reported SILC need to be performed using special curved or articulated instruments. The purpose of this study is to demonstrate our initial experience of SILC, which could be performed using the standard laparoscopic instruments. Material and methods Retrospective review of 14 patients who underwent SILC at Siriraj Hospital from May to December 2010, patient's demographic data, perioperative outcomes, early postoperative complications and pathological data were collected and analyzed. Results The mean age of all patients was 60 years. The most common operation with SILC was sigmoidectomy (n = 9, followed by right hemicolectomy (n = 2, left hemicolectomy (n = 1, anterior resection (n = 1, and total colectomy (n = 1. The trocar insertion techniques were multi-fascial incision using regular port (n = 11 and GelPOINT® (n = 3. The mean operative time was 155 minutes (range 90-280 and the mean estimate blood loss was 32.1 mL (range 10-100. All patients were successfully operated without conversion. The mean length of hospital stay was 9 days (range 5-20. There was no mortality. The pathological results revealed colorectal cancer (n = 12, neoplastic polyp (n = 1 and Familial adenomatous polyposis (FAP (n = 1. The mean number of lymph nodes retrieval was 16.6 (range 3-34. Conclusion SILC can successfully and safely be performed with standard laparoscopic instruments. This technique might be an alternative procedure to conventional laparoscopic colectomy with better cosmetic result.

  3. Pneumatic reduction of intussusception in children at Korle Bu Teaching Hospital: An initial experience

    Directory of Open Access Journals (Sweden)

    Yaw Boateng Mensah

    2011-01-01

    Full Text Available Background: Intussusception is a common abdominal emergency in children which necessitates prompt diagnosis and management. Nonsurgical methods of managing this condition are rapidly gaining popularity with fluoroscopic-guided pneumatic reduction being one of such methods that has been used with great success in many countries. We present our initial experience with fluoroscopic-guided pneumatic reduction of intussusception at Korle Bu Teaching Hospital which is also the first time the technique has been used in Ghana. Materials and Methods: A total of 18 children were enrolled in the study between August 2007 and February 2008 at Korle Bu Teaching Hospital, Accra, Ghana. Patients were given air enema under fluoroscopic-guidance using locally assembled equipment. The intraluminal pressure was monitored with a pressure gauge and was not permitted to go above 120 mmHg. A total of three attempts of 3 min each were allowed. Results: There were 12 males and 6 females. The average age of the patients was 8.3 months (SD= 3 months. Twelve (67% of the cases were reduced successfully while 6 (33% failed to reduce. A majority of those that did not reduced had symptoms for at least 2 days. Bowel perforation occurred in three (16.7% cases. Conclusion: Pneumatic reduction of intussusception is a cost-effective and rapid method of management of intussusception. It however has limitations like high reported rate of bowel perforation and limited ability to identify lead points. The benefits however seem to outweigh these challenges, such as fluoroscopic-guided pneumatic reduction has a very high success rate. Fluoroscopic guided pneumatic reduction should be considered as one of the primary modes of reduction in Ghana and other neighbouring countries that are yet to practice it.

  4. MR imaging-guided percutaneous cryotherapy for lung tumors: initial experience.

    Science.gov (United States)

    Liu, Shangang; Ren, Ruimei; Liu, Ming; Lv, Yubo; Li, Bin; Li, Chengli

    2014-09-01

    To evaluate prospectively the initial clinical experience of magnetic resonance (MR) imaging-guided percutaneous cryotherapy of lung tumors. MR imaging-guided percutaneous cryotherapy was performed in 21 patients with biopsy-proven lung tumors (12 men, 9 women; age range, 39-79 y). Follow-up consisted of contrast-enhanced chest computed tomography (CT) scan performed at 3-month intervals to assess tumor control; CT scanning was carried out for 12 months or until death. Cryotherapy procedures were successfully completed in all 21 patients. Pneumothorax occurred in 7 (33.3%) of 21 patients. Chest tube placement was required in one (4.8%) case. Hemoptysis was exhibited by 11 (52.4%) patients, and pleural effusion occurred in 6 (28.6%) patients. Other complications were observed in 14 (66.7%) patients. The mean follow-up period was 10.5 months (range, 9-12 mo) in patients who died. At month 12 of follow-up, 7 (33.3%) patients had a complete response to therapy, and 10 (47.6%) patients showed a partial response. In addition, two patients had stable disease, and two patients developed progressive disease; one patient developed a tumor in the liver, and the other developed a tumor in the brain. The 1-year local control rate was 81%, and 1-year survival rate was 90.5%. MR imaging-guided percutaneous cryotherapy appears feasible, effective, and minimally invasive for lung tumors. Copyright © 2014 SIR. Published by Elsevier Inc. All rights reserved.

  5. Social and Psychological Predictors of Initial Cigarette Smoking Experience: A Survey in Male College Students.

    Science.gov (United States)

    Menati, Walieh; Nazarzadeh, Milad; Bidel, Zeinab; Würtz, Morten; Menati, Rostam; Hemati, Rohollah; Yaghoubi, Maryam; Zareimanesh, Elham; Mohammadi, Mohammad Sabour; Akhlaghi Ardekani, Farzad; Tazval, Jafar; Delpisheh, Ali

    2016-01-01

    Knowledge about social and psychological risk factors for initial cigarette smoking experience (ICSE) is sparse. The present study aimed to estimate the prevalence of ICSE and to examine the psychological and social factors related to ICSE. In a cross-sectional survey, 1,511 male college students were recruited using multistage sampling techniques from four universities located within the city of Ilam, Iran. Self-administered multiple-choice questionnaires were distributed to students from March to June 2013. Risk factors for ICSE were evaluated using logistic regression models. Participants were 22.3 ± 2.4 years of age. ICSE prevalence was 30.6%. In multivariable adjusted analysis, risk taking behavior (odds ratio [OR] = 1.61; 95% confidence interval [CI] = 1.11-2.33), perceived peer smoking prevalence (OR = 2.48; 95% CI = 1.03-5.97), positive thoughts about smoking (OR = 1.06; 95% CI = 1.02-1.10), high self-efficacy (OR = 0.95, 95% CI [0.93, 0.98]), presence in smokers' gathering (OR = 4.45; 95% CI = 2.88-6.81), comity of smokers (OR = 2.56; 95% CI = 1.66, 3.92), very hard access to cigarettes (OR = 2.20; 95% CI = 1.16-4.16), close friends' medium reaction toward smoking (OR = 1.38; 95% CI = 1.02-1.88), and sporting activity (OR = 0.74; 95% CI = 0.56-0.98) were significantly associated with ICSE. This study identified that a combination of psychological and social variables account for up to 78% of the probability of ICSE. The most important protective factor against ICSE was physical activity, whereas the most important risk factor for ICSE was frequent gathering in the presence of smokers. © The Author(s) 2014.

  6. Initial clinical experience with multilumen brachytherapy catheters for accelerated partial breast irradiation.

    Science.gov (United States)

    Shah, Chirag; Ghilezan, Mihai; Arthur, Douglas; Wilkinson, John B; Keisch, Martin; Chen, Peter; Vicini, Frank A

    2012-01-01

    To review the initial experience of three institutions using multilumen catheters to deliver accelerated partial breast irradiation (APBI) and evaluate dosimetric improvements. Patients were eligible for this analysis if they met criteria for accelerated partial breast irradiation at their respective institution and were not enrolled on the national Phase III trial. Minimum guidelines for treatment planning from the National Surgical Adjuvant Breast and Bowel Project B-39/Radiation Therapy Oncology Group 0413 protocol were followed. Toxicities were coded using common toxicity criteria version 3.0 criteria. Sixty-two patients were analyzed as part of this study. Median skin spacing was 11mm with a median skin dose of 86.9% (% of prescription dose [PD]). Median rib dose was 76.1% of the PD (range, 4.3-155.7%). The V(90), V(95), and V(100) of the PD for the planning target volume evaluation was 95.4%, 95.2%, and 80.3%, respectively. Seven patients had both skin and rib spacing skin dose and rib dose being 113.4% and 130.9% of the PD. For these cases, the median V(90), V(95), and V(100) of the PD was 99.2%, 94.3%, and 81.1%, respectively, whereas the median V(150) and V(200) were 22.5cc and 7.4cc. Overall, Grade I and II radiation dermatitis were noted in 41.9% and 6.5% of patients. The multilumen device led to improvements in target coverage and normal structure doses compared with traditionally accepted guidelines. Similar toxicities were seen compared with single-lumen devices, even in patients with skin and rib spacing Brachytherapy Society. Published by Elsevier Inc. All rights reserved.

  7. Initial Experience with Elective Perventricular Melody Valve Placement in Small Patients.

    Science.gov (United States)

    Gupta, Aamisha; Kenny, Damien; Caputo, Massimo; Amin, Zahid

    2017-03-01

    Perventricular Melody valve placement has been described as a bailout approach or alternative RVOT approach in patients >30 kg. We present three patients hybrid pulmonary valve replacement were reviewed. The subcostal approach was performed without sternotomy with the sheath introduced through the diaphragmatic surface of the right ventricle. Diagnoses included tetralogy of Fallot (n = 3) and truncus arteriosus (n = 2). Mean weight was 16.2 kg (range 4.7-28.1 kg). Four patients had RV-PA conduits (size: 14-21 mm), and the fifth patient had a transannular patch. All patients met criteria for surgical valve replacement. Technical success was 100%. In two patients with absent pulmonary valve, the stent migrated during advancement of the delivery sheath. These stents were anchored in the distal main pulmonary artery (n = 1) or branch pulmonary artery (n = 1) without sequela. Tricuspid valve chordal injury occurred in one patient, where transesophageal echocardiogram (TEE) was not utilized. No patient required conversion to cardiopulmonary bypass. One patient with absent pulmonary valve died on follow-up as a consequence of severe airway compromise. Our initial experience demonstrates that the perventricular valve can be placed safely in small-sized patients. Advancement of the melody ensemble may be difficult and may cause stent migration. We conclude that the technique is feasible in small-sized patients and that prevention of complications includes placement of the stent at the time of the valve and TEE assistance in reducing tricuspid valve injury.

  8. Initial experience with implantation of novel dual layer flow-diverter device FRED.

    Science.gov (United States)

    Poncyljusz, Wojciech; Sagan, Leszek; Safranow, Krzysztof; Rać, Monika

    2013-09-01

    Flow-diverting stents can help treat complex and wide-necked cerebral aneurysms. The aim of the study was to evaluate initial experiences related to the safety and effectiveness of eight aneurysms treated with a new dual layer coverage designed flow-diverter device. In 2012 Fred flow-diverter devices were used to treat 8 unruptured wide neck (dome-neck ratio ≤ 1.5) and sidewall aneurysms in 6 patients. All aneurysms were located in the anterior circulation on the internal carotid artery (ICA). In 4 larger aneurysms (> 10 mm) one 3D coil in association with Fred was used to reduce potential incidence of postoperative subarachnoid haemorrhage (SAH). Dual antiplatelet therapy was administered before the procedure and continued for 3 months after it. Clinical parameters, aneurysm features and 3-month follow-up angiograms are presented. All 6 patients with 8 aneurysms were successfully stented with the Fred flow-diverter device and were discharged in generally good condition on dual-antiplatelet therapy. No complications were related to the procedure. In 5 cases digital subtraction angiography (DSA) control examination was performed after 3 months, showing complete occlusion of the aneurysms with patency of the parent artery. In 1 case thrombosis of the Fred occurred but without any clinical consequences because of cross-flow from the other side. Use of the Fred flow-diverter device was efficacious in all 8 treated cerebral aneurysms. The system seems to be promising as a flow diverter with certain characteristics, which allow for easy delivery and implantation. Further clinical evaluation with a larger group of patients is needed.

  9. Software Open Source, Software Gratis?

    OpenAIRE

    Rakhmawati, Nur Aini

    2006-01-01

    Berlakunya Undang – undang Hak Atas Kekayaan Intelektual (HAKI), memunculkan suatu alternatif baru untuk menggunakan software open source. Penggunaan software open source menyebar seiring dengan isu global pada Information Communication Technology (ICT) saat ini. Beberapa organisasi dan Perusahaan mulai menjadikan software open source sebagai pertimbangan. Banyak konsep mengenai software open source ini. Mulai dari software yang gratis sampai software tidak berlisensi. Tidak sepenuhnya isu so...

  10. Applying Open Source Software in a Development Context: Expectations and Experiences. A Case Study of a University in Uganda

    Science.gov (United States)

    van Reijswoud, Victor; Mulo, Emmanuel

    2006-01-01

    Over recent years the issue of free and open source software (FOSS) for development in less developed countries (LDCs) has received increasing attention. In the beginning the benefits of FOSS for lower developed countries was only stressed by small groups of idealists like Richard Stallman. Now, however, it is moving into the hands of large…

  11. Greening of a Campus through Waste Management Initiatives: Experience from a Higher Education Institution in Thailand

    Science.gov (United States)

    Tangwanichagapong, Siwaporn; Nitivattananon, Vilas; Mohanty, Brahmanand; Visvanathan, Chettiyappan

    2017-01-01

    Purpose: This paper aims to describe the effects of 3R (reduce, reuse and recycle) waste management initiatives on a campus community. It ascertains the environmental attitudes and opinions of the residents and investigates their behavioral responses to waste management initiatives. Practical implications for enhancing sustainable waste management…

  12. Initial imperfections for fea of tubular beams based on validated experiment results

    NARCIS (Netherlands)

    Pavlovic, M.; Veljkovic, M.; Dubina, D.; Ungureanu, V.

    2016-01-01

    The experiment data available on 4-point bending experiments performed in Aus-tralia and Europe on tubular section beams are validated by FEA. Large scattering of available experiment results is investigated by detailed analysis of different geometrical imperfections. Loading set-up is analysed

  13. Single-access laparoscopic adjustable gastric band removal: technique and initial experience.

    Science.gov (United States)

    Dapri, Giovanni; El Mourad, Haicam; Mathonet, Perrine; Delaporte, Amélie; Himpens, Jacques; Cadière, Guy Bernard; Greve, Jan Willem

    2013-02-01

    Single-access laparoscopy (SAL) has gained significant interest in recent years. Potential benefits, beyond cosmetic outcomes, could be reduction of abdominal trauma, decreased risk of incisional hernia and diminished postoperative pain. Technique and initial experience in patients submitted to laparoscopic adjustable gastric band removal (LAGBR) through SAL is reported here. Between December 2009 and March 2012, 14 patients (9 females, 5 males) underwent LAGBR through SAL. Indications for operation were band intolerance (11), pouch dilatation (2) and insufficient weight loss (1). The mean age was 40.3 ± 9.1 years (range 26-57), and the mean interval time between LAGB placement and removal was 94.7 ± 41.9 months (range 37-157). The mean weight and the mean body mass index at the time of LAGBR were 89.3 ± 17.6 kg (range 65-119) and 30.6 ± 4.5 kg/m(2) (range 25.3-36.7), respectively. Technically, the previous port site scar was used as the single-access site to the abdominal cavity. An 11-mm reusable trocar was adopted for a 10-mm regular scope, besides curved reusable instruments. No patients required conversion to open surgery and none necessitated additional trocars. The mean laparoscopic time was 24.6 ± 7.9 min (range 13-37), and the mean final scar length was 3.6 ± 0.3 cm (range 3-4). Two patients experienced early postoperative complications. The mean hospital stay was 1.3 ± 1.1 days (range 1-5). The mean follow-up time was of 18 ± 9.8 months (range 3-30), and there were no late complications. LAGBR can be safely performed through SAL. Thanks to this technique, the laparoscopic working triangulation is established as well as the ergonomic positions of the surgeon. Due the use of only reusable material, the cost of this SAL remains similar to multiport laparoscopy.

  14. Supporting ITM Missions by Observing System Simulation Experiments: Initial Design, Challenges and Perspectives

    Science.gov (United States)

    Yudin, V. A.; England, S.; Matsuo, T.; Wang, H.; Immel, T. J.; Eastes, R.; Akmaev, R. A.; Goncharenko, L. P.; Fuller-Rowell, T. J.; Liu, H.; Solomon, S. C.; Wu, Q.

    2014-12-01

    We review and discuss the capability of novel configurations of global community (WACCM-X and TIME-GCM) and planned-operational (WAM) models to support current and forthcoming space-borne missions to monitor the dynamics and composition of the Ionosphere-Thermosphere-Mesosphere (ITM) system. In the specified meteorology model configuration of WACCM-X, the lower atmosphere is constrained by operational analyses and/or short-term forecasts provided by the Goddard Earth Observing System (GEOS-5) of GMAO/NASA/GSFC. With the terrestrial weather of GEOS-5 and updated model physics, WACCM-X simulations are capable to reproduce the observed signatures of the perturbed wave dynamics and ion-neutral coupling during recent (2006-2013) stratospheric warming events, short-term, annual and year-to-year variability of prevailing flows, planetary waves, tides, and composition. With assimilation of the NWP data in the troposphere and stratosphere the planned-operational configuration of WAM can also recreate the observed features of the ITM day-to-day variability. These "terrestrial-weather" driven whole atmosphere simulations, with day-to-day variable solar and geomagnetic inputs, can provide specification of the background state (first guess) and errors for the inverse algorithms of forthcoming NASA ITM missions, such as ICON and GOLD. With two different viewing geometries (sun-synchronous, for ICON and geostationary for GOLD) these missions promise to perform complimentary global observations of temperature, winds and constituents to constrain the first-principle space weather forecast models. The paper will discuss initial designs of Observing System Simulation Experiments (OSSE) in the coupled simulations of TIME-GCM/WACCM-X/GEOS5 and WAM/GIP. As recognized, OSSE represent an excellent learning tool for designing and evaluating observing capabilities of novel sensors. The choice of assimilation schemes, forecast and observational errors will be discussed along with challenges

  15. Initial romanian experience with green light hps 120 w laser in bph

    Science.gov (United States)

    P., Geavlete; Gh., Niţă; B., Geavlete

    2008-01-01

    Introduction and objectives:Potassium-titanyl-phosphate (KTP) laser photoselective vaporization prostatectomy (PVP) is a relatively new technology for the management of benign prostatic hyperplasia (BPH). We reviewed our initial experience regarding the efficacy and safety of this technique for symptomatic and obstructive BPH. Material and methods: During the last year, 35 patients with a mean age of 65.3 years (between 53 and 80) and symptomatic BPH were treated by laser prostatectomy using KTP/532 laser energy at 120W. The procedure was performed through a 21F continuous-flow cystoscope with normal saline as irrigant. All patients underwent standard urologic evaluation using the International Prostate Symptom Score (IPSS), the urinary peak flow rate (Qmax), ultrasound measurement of prostate volume and residual urine volume, assay of prostate specific antigen (PSA) and digital rectal examination (DRE). The mean prostatic volume was 45cm3 (range 30–70cm3). The patients were reassessed postoperatively at 3 and 6 months. Results: In all cases, KTP laser vaporization was successfully performed, with a mean operating time of 57 minutes (range 20-120 minutes). In most cases, we used just one fibre, the mean energy released being 170.000 Joules (range 80.000-270.000). The mean hospital stay was 24 hours. No major complications occurred intraoperatively or postoperatively, and no transfusions were necessary. All patients were catheter-free after 1 month. At 3 and 6 months, the mean urinary peak flow increased from the preoperative value of 8.5mL/sec to 23.7mL/sec and 21.2mL/sec, respectively. The mean IPSS decreased from 19.0 to 9.5 and 7.5 at 3 and 6 months, and the mean post-voiding residual volume (PVR) decreased from 90.5 to 30.5mL and 15.0 mL. Two patients were admitted for secondary hematuria and urinary infection, and 7 patients presented irritative low urinary tract symptoms during their first postoperative check-up. Conclusions: BPH photoselective vaporization

  16. Myocardial stress perfusion magnetic resonance: initial experience in a pediatric and young adult population using regadenoson.

    Science.gov (United States)

    Noel, Cory V; Krishnamurthy, Ramkumar; Moffett, Brady; Krishnamurthy, Rajesh

    2017-03-01

    Dipyridamole and adenosine are traditional pharmacological stressors for myocardial perfusion. Regadenoson, a selective adenosine A2A agonist, has a lower side effect profile with lower incidence of bronchospasm and bradycardia. There is a growing need for myocardial perfusion assessment within pediatrics. There is no report on the utility of regadenoson as a stress agent in children. To observe the safety and feasibility of regadenoson as a pharmacologic stressor for perfusion cardiac MR in a pilot cohort of pediatric patients weighing more than 40 kg who have congenital heart disease and pediatric acquired heart disease. We reviewed our initial experience with regadenoson stress cardiac MR in 31 pediatric patients 15.8 ± 1.7 years (range 12-22 years) with congenital heart disease and acquired heart disease. Mean patient weight was 60 ± 15 kg (range of 40-93 kg). All patients underwent cardiac MR because of concern for ischemia. The cohort included a heterogeneous group of patients at a pediatric institution with potential risk for ischemia. Subjects' heart rate and blood pressure were monitored and pharmacologic stress was induced by injection of 400 mcg of regadenoson. We evaluated their hemodynamic response and adverse effects using changes in vital signs and onset of symptoms. A pediatric cardiologist and radiologist qualitatively assessed myocardial perfusion and viability images. One child was unable to complete the stress perfusion portion of the examination, but did complete the remaining portion of the CMR. Resting heart rate was 72 ± 14 beats per minute (bpm) and rose to peak of 124 ± 17 bpm (95 ± 50% increase, P regadenoson. Image quality was considered good or diagnostic in all cases. Three patients had irreversible perfusion defects. Four patients had reversible perfusion defects. Nine of the patients underwent cardiac catheterization with angiography and the findings showed excellent agreement. Regadenoson might be a

  17. Initial experiences of implementation of functional integration (FI) in LEPRA India projects in Orissa.

    Science.gov (United States)

    Rao, V Prabhakara; Bhuskade, R A; Raju, M Sathi; Rao, P V Ranganadha; Desikan, K V

    2002-06-01

    In 2000, the Government of the State of Orissa (population 37 million) in India decided to introduce functional integration for the control of leprosy, in place of the long-established vertical programme, using the general health services and the primary health care system. This paper describes the initial (9 months) experience of implementing this strategy in two projects run by LEPRA India. One of these, in the district of Koraput, was established in 1991 and covers a population of 1.5 million people. The other, in Kalahandi district, started in 1997 and covers a population of 600,000. Both projects operate under difficult conditions with regard to terrain, the use of numerous tribal languages, illiteracy, water shortage, poor roads and communications. The preparatory phase included intensive health education of the public on leprosy, using a wide range of educational media and techniques. At the same time, LEPRA India supported the Government in the training and orientation of trainers, medical officers, primary health care staff and female health workers at village level. In all, over 2000 were trained. This paper describes all aspects of the implementation of functional integration in these two areas. In the 9-month period, 4207 suspect cases were referred to medical officers by health workers, but only 256 (6%) were confirmed as having leprosy. There were 169 confirmed self-reporting cases. Despite the clearly understood intention to involve primary health staff in case detection, 67% of all cases were in fact detected by LEPRA India, possibly due to overlapping attendance at clinics by vertical and general staff. There is obviously a need for further training of the general staff since only 6% of cases referred by them were confirmed as having leprosy. Steps must also be taken to ensure that the emphasis on case detection, confirmation and treatment shifts from the vertical to the general health staff. The supply of anti-leprosy drugs and steroids to primary

  18. Myocardial stress perfusion magnetic resonance: initial experience in a pediatric and young adult population using regadenoson

    Energy Technology Data Exchange (ETDEWEB)

    Noel, Cory V. [Baylor College of Medicine, Department of Pediatric Cardiology, Houston, TX (United States); Texas Children' s Hospital, Department of Pediatric Cardiology, Houston, TX (United States); Krishnamurthy, Ramkumar; Krishnamurthy, Rajesh [Texas Children' s Hospital, Department of Radiology, Houston, TX (United States); Moffett, Brady [Texas Children' s Hospital, Department of Pharmacology, Houston, TX (United States)

    2017-03-15

    Dipyridamole and adenosine are traditional pharmacological stressors for myocardial perfusion. Regadenoson, a selective adenosine A2A agonist, has a lower side effect profile with lower incidence of bronchospasm and bradycardia. There is a growing need for myocardial perfusion assessment within pediatrics. There is no report on the utility of regadenoson as a stress agent in children. To observe the safety and feasibility of regadenoson as a pharmacologic stressor for perfusion cardiac MR in a pilot cohort of pediatric patients weighing more than 40 kg who have congenital heart disease and pediatric acquired heart disease. We reviewed our initial experience with regadenoson stress cardiac MR in 31 pediatric patients 15.8 ± 1.7 years (range 12-22 years) with congenital heart disease and acquired heart disease. Mean patient weight was 60 ± 15 kg (range of 40-93 kg). All patients underwent cardiac MR because of concern for ischemia. The cohort included a heterogeneous group of patients at a pediatric institution with potential risk for ischemia. Subjects' heart rate and blood pressure were monitored and pharmacologic stress was induced by injection of 400 mcg of regadenoson. We evaluated their hemodynamic response and adverse effects using changes in vital signs and onset of symptoms. A pediatric cardiologist and radiologist qualitatively assessed myocardial perfusion and viability images. One child was unable to complete the stress perfusion portion of the examination, but did complete the remaining portion of the CMR. Resting heart rate was 72 ± 14 beats per minute (bpm) and rose to peak of 124 ± 17 bpm (95 ± 50% increase, P < 0.005) with regadenoson. Image quality was considered good or diagnostic in all cases. Three patients had irreversible perfusion defects. Four patients had reversible perfusion defects. Nine of the patients underwent cardiac catheterization with angiography and the findings showed excellent agreement. Regadenoson might be a safe and

  19. Software engineering

    CERN Document Server

    Sommerville, Ian

    2010-01-01

    The ninth edition of Software Engineering presents a broad perspective of software engineering, focusing on the processes and techniques fundamental to the creation of reliable, software systems. Increased coverage of agile methods and software reuse, along with coverage of 'traditional' plan-driven software engineering, gives readers the most up-to-date view of the field currently available. Practical case studies, a full set of easy-to-access supplements, and extensive web resources make teaching the course easier than ever.

  20. E-learning course: Basis of Harvest and Preservation of Tissues – design and initial experience

    Directory of Open Access Journals (Sweden)

    Pavel Měřička

    2014-05-01

    Full Text Available Background: The design and initial experience with the e-learning course “Basis of Harvest and Preservation of Tissues” used as a support of an elective subject is presented. The aim of the e-learning course was to enable the students to learn the theoretical principles of the subject individually and to present the gained knowledge at the final seminar. Methods: All functions of the course were operated in Moodle, local application of the Charles University in Prague, Faculty of Medicine in Hradec Králové. The course was divided into 3 main topics corresponding with topics of lectures: 1. Principles of tissue and organ donation, 2. Low temperature preservation of cells, tissues and organs, 3. Quality and safety assurance in practice of tissue and procurement establishments. A test consisting of 5 questions selected randomly from the bank of questions followed each topic. If the student answers correctly at least 3 questions he is allowed to pass to the next topic. The fourth topic “Basic processes in the tissue establishment and principles of their validation” was added into the electronic version as a tool for repeating and improving of knowledge. The fifth topic was represented by a database for uploading theses presented by students at the final seminar. The final test consisted of 15 questions (5 ones from each basic topic. It was necessary to answer correctly at least 10 questions to receive a certificate of completing the course. Results: The course was put into operation during the summer term of the academic year 2012/2013. To the date 15 of September the total of 23 students enrolled (17, i.e. all students of the elective subject in the Czech version, 2 students of this subject in the English version, 2 postgraduate students and 2 medical doctors. All enrolled students used the course for on-line learning, downloading, or printing course study materials. All undergraduate students were obliged to use it for preparation

  1. An initial experience with a digital drainage system during the postoperative period of pediatric thoracic surgery.

    Science.gov (United States)

    Costa, Altair da Silva; Bachichi, Thiago; Holanda, Caio; Rizzo, Luiz Augusto Lucas Martins De

    2016-01-01

    To report an initial experience with a digital drainage system during the postoperative period of pediatric thoracic surgery. This was a prospective observational study involving consecutive patients, ≤ 14 years of age, treated at a pediatric thoracic surgery outpatient clinic, for whom pulmonary resection (lobectomy or segmentectomy via muscle-sparing thoracotomy) was indicated. The parameters evaluated were air leak (as quantified with the digital system), biosafety, duration of drainage, length of hospital stay, and complications. The digital system was used in 11 children (mean age, 5.9 ± 3.3 years). The mean length of hospital stay was 4.9 ± 2.6 days, the mean duration of drainage was 2.5 ± 0.7 days, and the mean drainage volume was 270.4 ± 166.7 mL. The mean maximum air leak flow was 92.78 ± 95.83 mL/min (range, 18-338 mL/min). Two patients developed postoperative complications (atelectasis and pneumonia, respectively). The use of this digital system facilitated the decision-making process during the postoperative period, reducing the risk of errors in the interpretation and management of air leaks. Relatar a experiência inicial com um sistema de drenagem digital no pós-operatório de cirurgia torácica pediátrica. Estudo observacional e prospectivo envolvendo pacientes consecutivos do ambulatório de cirurgia torácica pediátrica da instituição, com idade até 14 anos, e com indicação de ressecção pulmonar (lobectomia e/ou segmentectomia através de toracotomia poupadora muscular). Os parâmetros avaliados foram perda aérea (quantificada com o sistema digital), biossegurança, tempo de drenagem, tempo de internação e complicações. O sistema digital foi utilizado em 11 crianças, com média de idade de 5,9 ± 3,3 anos. A média do tempo de internação foi de 4,9 ± 2,6 dias, a de tempo de drenagem foi de 2,5 ± 0,7 dias, e a de volume de drenagem foi de 270,4 ± 166,7 ml. A média da perda aérea máxima foi de 92,78 ± 95,83 ml

  2. Use of Simulation in Nursing Education: Initial Experiences on a European Union Lifelong Learning Programme--Leonardo Da Vinci Project

    Science.gov (United States)

    Terzioglu, Fusun; Tuna, Zahide; Duygulu, Sergul; Boztepe, Handan; Kapucu, Sevgisun; Ozdemir, Leyla; Akdemir, Nuran; Kocoglu, Deniz; Alinier, Guillaume; Festini, Filippo

    2013-01-01

    Aim: The aim of this paper is to share the initial experiences on a European Union (EU) Lifelong Learning Programme Leonardo Da Vinci Transfer of Innovation Project related to the use of simulation-based learning with nursing students from Turkey. The project started at the end of the 2010 involving 7 partners from 3 different countries including…

  3. Initial Experiment in Using a Powered Parafoil for Employment of Intelligence, Surveillance, and Reconnaissance (ISR) Unattended Ground Sensors (UGS)

    National Research Council Canada - National Science Library

    Kolodny, Michael

    2004-01-01

    Experiments were run by the U.S. Army Research Laboratory at Yuma Proving Ground, AZ, on 10 and 12 June 2004 to obtain an initial assessment of the viability of using a powered parafoil as an unmanned air vehicle for employment...

  4. Characterizing Design Cognition of High School Students: Initial Analyses Comparing Those with and without Pre-Engineering Experiences

    Science.gov (United States)

    Wells, John; Lammi, Matthew; Gero, John; Grubbs, Michael E.; Paretti, Marie; Williams, Christopher

    2016-01-01

    Reported in this article are initial results from of a longitudinal study to characterize the design cognition and cognitive design styles of high school students with and without pre-engineering course experience over a 2-year period, and to compare them with undergraduate engineering students. The research followed a verbal protocol analysis…

  5. The Relationship of a Pilot's Educational Background, Aeronautical Experience and Recency of Experience to Performance In Initial Training at a Regional Airline

    Science.gov (United States)

    Shane, Nancy R.

    The purpose of this study was to determine how a pilot's educational background, aeronautical experience and recency of experience relate to their performance during initial training at a regional airline. Results show that variables in pilots' educational background, aeronautical experience and recency of experience do predict performance in training. The most significant predictors include years since graduation from college, multi-engine time, total time and whether or not a pilot had military flying experience. Due to the pilot shortage, the pilots entering regional airline training classes since August 2013 have varied backgrounds, aeronautical experience and recency of experience. As explained by Edward Thorndike's law of exercise and the law of recency, pilots who are actively using their aeronautical knowledge and exercising their flying skills should exhibit strong performance in those areas and pilots who have not been actively using their aeronautical knowledge and exercising their flying skills should exhibit degraded performance in those areas. Through correlation, chi-square and multiple regression analysis, this study tests this theory as it relates to performance in initial training at a regional airline.

  6. HORACE: Software for the analysis of data from single crystal spectroscopy experiments at time-of-flight neutron instruments

    Energy Technology Data Exchange (ETDEWEB)

    Ewings, R.A.; Buts, A.; Le, M.D. [ISIS Facility, STFC Rutherford Appleton Laboratory, Harwell Campus, Didcot OX11 0QX (United Kingdom); Duijn, J. van [Departamento de Mecánica, Universidad de Córdoba, 14071 Córdoba (Spain); Bustinduy, I. [ESS Bilbao, Poligono Ugaldeguren III, Pol. A, 7B - 48170 Zamudio, Bizkaia – País Vasco (Spain); Perring, T.G., E-mail: toby.perring@stfc.ac.uk [ISIS Facility, STFC Rutherford Appleton Laboratory, Harwell Campus, Didcot OX11 0QX (United Kingdom); London Centre for Nanotechnology and Department of Physics and Astronomy, University College London, Gower Street, London WC1E 6BT (United Kingdom)

    2016-10-21

    The HORACE suite of programs has been developed to work with large multiple-measurement data sets collected from time-of-flight neutron spectrometers equipped with arrays of position-sensitive detectors. The software allows exploratory studies of the four dimensions of reciprocal space and excitation energy to be undertaken, enabling multi-dimensional subsets to be visualized, algebraically manipulated, and models for the scattering to simulated or fitted to the data. The software is designed to be an extensible framework, thus allowing user-customized operations to be performed on the data. Examples of the use of its features are given for measurements exploring the spin waves of the simple antiferromagnet RbMnF{sub 3} and ferromagnetic iron, and the phonons in URu{sub 2}Si{sub 2}.

  7. HORACE: Software for the analysis of data from single crystal spectroscopy experiments at time-of-flight neutron instruments

    Science.gov (United States)

    Ewings, R. A.; Buts, A.; Le, M. D.; van Duijn, J.; Bustinduy, I.; Perring, T. G.

    2016-10-01

    The HORACE suite of programs has been developed to work with large multiple-measurement data sets collected from time-of-flight neutron spectrometers equipped with arrays of position-sensitive detectors. The software allows exploratory studies of the four dimensions of reciprocal space and excitation energy to be undertaken, enabling multi-dimensional subsets to be visualized, algebraically manipulated, and models for the scattering to simulated or fitted to the data. The software is designed to be an extensible framework, thus allowing user-customized operations to be performed on the data. Examples of the use of its features are given for measurements exploring the spin waves of the simple antiferromagnet RbMnF3 and ferromagnetic iron, and the phonons in URu2Si2.

  8. Analysis of lipid experiments (ALEX: a software framework for analysis of high-resolution shotgun lipidomics data.

    Directory of Open Access Journals (Sweden)

    Peter Husen

    Full Text Available Global lipidomics analysis across large sample sizes produces high-content datasets that require dedicated software tools supporting lipid identification and quantification, efficient data management and lipidome visualization. Here we present a novel software-based platform for streamlined data processing, management and visualization of shotgun lipidomics data acquired using high-resolution Orbitrap mass spectrometry. The platform features the ALEX framework designed for automated identification and export of lipid species intensity directly from proprietary mass spectral data files, and an auxiliary workflow using database exploration tools for integration of sample information, computation of lipid abundance and lipidome visualization. A key feature of the platform is the organization of lipidomics data in "database table format" which provides the user with an unsurpassed flexibility for rapid lipidome navigation using selected features within the dataset. To demonstrate the efficacy of the platform, we present a comparative neurolipidomics study of cerebellum, hippocampus and somatosensory barrel cortex (S1BF from wild-type and knockout mice devoid of the putative lipid phosphate phosphatase PRG-1 (plasticity related gene-1. The presented framework is generic, extendable to processing and integration of other lipidomic data structures, can be interfaced with post-processing protocols supporting statistical testing and multivariate analysis, and can serve as an avenue for disseminating lipidomics data within the scientific community. The ALEX software is available at www.msLipidomics.info.

  9. Flip, feedback and fly: Using LOOP to enhance the professional experience of initial teacher education

    National Research Council Canada - National Science Library

    Phillipson, Shane N; Phillipson, Sivanes; Cooper, David G

    2015-01-01

    .... Problems can arise, however, when the evaluation of their professional experience against the Standards shifts from the providers of teacher education programmes to school-based supervising teachers...

  10. Effect of flaming on Hydrocotyle ranunculoides L.f. survival. An initial experiment

    NARCIS (Netherlands)

    Burg, van der W.J.; Michielsen, J.G.P.

    2010-01-01

    The background of this pilot experiment was to find out if treatment in nature with hydrogen peroxide would be feasible as control measure. The experiment was designed to 1. try to raise plants in containers, and 2. to observe the effect of hydrogen spraying on the plants. This would allow to

  11. Initial Results on Neutralized Drift Compression Experiments (NDCX-IA) for High Intensity Ion Beam

    CERN Document Server

    Roy, Prabir K; Baca, David; Bieniosek, Frank; Coleman, Joshua E; Davidson, Ronald C; Efthimion, Philip; Eylon, Shmuel; Gilson, Erik P; Grant Logan, B; Greenway, Wayne; Henestroza, Enrique; Kaganovich, Igor D; Leitner, Matthaeus; Rose, David; Sefkow, Adam; Sharp, William M; Shuman, Derek; Thoma, Carsten H; Vanecek, David; Waldron, William; Welch, Dale; Yu, Simon

    2005-01-01

    Ion beam neutralization and compression experiments are designed to determine the feasibility of using compressed high intensity ion beams for high energy density physics (HEDP) experiments and for inertial fusion power. To quantitatively ascertain the various mechanisms and methods for beam compression, the Neutralized Drift Compression Experiment (NDCX) facility is being constructed at Lawrence Berkeley National Laboratory (LBNL). In the first compression experiment, a 260 KeV, 25 mA, K+ ion beam of centimeters size is radially compressed to a mm size spot by neutralization in a meter-long plasma column and beam peak current is longitudinally compressed by an induction velocity tilt core. Instrumentation, preliminary results of the experiments, and practical limits of compression are presented. These include parameters such as emittance, degree of neutralization, velocity tilt time profile, and accuracy of measurements (fast and spatially high resolution diagnostic) are discussed.

  12. Formal Validation of Aerospace Software

    Science.gov (United States)

    Lesens, David; Moy, Yannick; Kanig, Johannes

    2013-08-01

    Any single error in critical software can have catastrophic consequences. Even though failures are usually not advertised, some software bugs have become famous, such as the error in the MIM-104 Patriot. For space systems, experience shows that software errors are a serious concern: more than half of all satellite failures from 2000 to 2003 involved software. To address this concern, this paper addresses the use of formal verification of software developed in Ada.

  13. Software design practice using two SCADA software packages

    DEFF Research Database (Denmark)

    Basse, K.P.; Christensen, Georg Kronborg; Frederiksen, P. K.

    1996-01-01

    Typical software development for manufacturing control is done either by specialists with consideral real-time programming experience or done by the adaptation of standard software packages for manufacturing control. After investigation and test of two commercial software packages: "In......Touch" and "Fix", it is argued, that a more efficient software solution can be achieved by utilising an integrated specification for SCADA and PLC-programming. Experiences gained from process control is planned investigated for descrete parts manufacturing....

  14. Development of fast patient position verification software using 2D-3D image registration and its clinical experience.

    Science.gov (United States)

    Mori, Shinichiro; Kumagai, Motoki; Miki, Kentaro; Fukuhara, Riki; Haneishi, Hideaki

    2015-09-01

    To improve treatment workflow, we developed a graphic processing unit (GPU)-based patient positional verification software application and integrated it into carbon-ion scanning beam treatment. Here, we evaluated the basic performance of the software. The algorithm provides 2D/3D registration matching using CT and orthogonal X-ray flat panel detector (FPD) images. The participants were 53 patients with tumors of the head and neck, prostate or lung receiving carbon-ion beam treatment. 2D/3D-ITchi-Gime (ITG) calculation accuracy was evaluated in terms of computation time and registration accuracy. Registration calculation was determined using the similarity measurement metrics gradient difference (GD), normalized mutual information (NMI), zero-mean normalized cross-correlation (ZNCC), and their combination. Registration accuracy was dependent on the particular metric used. Representative examples were determined to have target registration error (TRE) = 0.45 ± 0.23 mm and angular error (AE) = 0.35 ± 0.18° with ZNCC + GD for a head and neck tumor; TRE = 0.12 ± 0.07 mm and AE = 0.16 ± 0.07° with ZNCC for a pelvic tumor; and TRE = 1.19 ± 0.78 mm and AE = 0.83 ± 0.61° with ZNCC for lung tumor. Calculation time was less than 7.26 s.The new registration software has been successfully installed and implemented in our treatment process. We expect that it will improve both treatment workflow and treatment accuracy. © The Author 2015. Published by Oxford University Press on behalf of The Japan Radiation Research Society and Japanese Society for Radiation Oncology.

  15. EvOligo: A Novel Software to Design and Group Libraries of Oligonucleotides Applicable for Nucleic Acid-Based Experiments.

    Science.gov (United States)

    Milewski, Marek C; Kamel, Karol; Kurzynska-Kokorniak, Anna; Chmielewski, Marcin K; Figlerowicz, Marek

    2017-10-01

    Experimental methods based on DNA and RNA hybridization, such as multiplex polymerase chain reaction, multiplex ligation-dependent probe amplification, or microarray analysis, require the use of mixtures of multiple oligonucleotides (primers or probes) in a single test tube. To provide an optimal reaction environment, minimal self- and cross-hybridization must be achieved among these oligonucleotides. To address this problem, we developed EvOligo, which is a software package that provides the means to design and group DNA and RNA molecules with defined lengths. EvOligo combines two modules. The first module performs oligonucleotide design, and the second module performs oligonucleotide grouping. The software applies a nearest-neighbor model of nucleic acid interactions coupled with a parallel evolutionary algorithm to construct individual oligonucleotides, and to group the molecules that are characterized by the weakest possible cross-interactions. To provide optimal solutions, the evolutionary algorithm sorts oligonucleotides into sets, preserves preselected parts of the oligonucleotides, and shapes their remaining parts. In addition, the oligonucleotide sets can be designed and grouped based on their melting temperatures. For the user's convenience, EvOligo is provided with a user-friendly graphical interface. EvOligo was used to design individual oligonucleotides, oligonucleotide pairs, and groups of oligonucleotide pairs that are characterized by the following parameters: (1) weaker cross-interactions between the non-complementary oligonucleotides and (2) more uniform ranges of the oligonucleotide pair melting temperatures than other available software products. In addition, in contrast to other grouping algorithms, EvOligo offers time-efficient sorting of paired and unpaired oligonucleotides based on various parameters defined by the user.

  16. Initial experience with a new quantitative assessment tool for fluorescent imaging in peripheral artery disease.

    Science.gov (United States)

    Rieß, Henrik Christian; Duprée, Anna; Behrendt, Christian-Alexander; Kölbel, Tilo; Debus, Eike Sebastian; Larena-Avellaneda, Axel; Russ, Detlef; Wipper, Sabine

    2017-08-01

    Perioperative evaluation in peripheral artery disease (PAD) by common vascular diagnostic tools is limited by open wounds, medial calcinosis or an altered collateral supply of the foot. Indocyanine green fluorescent imaging (ICG-FI) has recently been introduced as an alternative tool, but so far a standardized quantitative assessment of tissue perfusion in vascular surgery has not been performed for this purpose. The aim of this feasibility study was to investigate a new software for quantitative assessment of tissue perfusion in patients with PAD using indocyanine green fluorescent imaging (ICG-FI) before and after peripheral bypass grafting. Indocyanine green fluorescent imaging was performed in seven patients using the SPY Elite system before and after peripheral bypass grafting for PAD (Rutherford III-VI). Visual and quantitative evaluation of tissue perfusion was assessed in an area of low perfusion (ALP) and high perfusion (AHP), each by three independent investigators. Data assessment was performed offline using a specially customized software package (Institute for Laser Technology, University Ulm, GmbH). Slope of fluorescent intensity (SFI) was measured as time-intensity curves. Values were compared to ankle-brachial index (ABI), slope of oscillation (SOO), and time to peak (TTP) obtained from photoplethysmography (PPG). All measurements before and after surgery were successfully performed, showing that ABI, TTP, and SOO increased significantly compared to preoperative values, all being statistically significant (P < 0.05), except for TTP (p = 0.061). Further, SFI increased significantly in both ALP and AHP (P < 0.05) and correlated considerably with ABI, TTP, and SOO (P < 0.05). In addition to ABI and slope of oscillation (SOO), the ICG-FI technique allows visual assessment in combination with quantitative assessment of tissue perfusion in patients with PAD. Ratios related to different perfusion patterns and SFI seem to be useful tools to reduce factors

  17. SOFTWARE OPEN SOURCE, SOFTWARE GRATIS?

    Directory of Open Access Journals (Sweden)

    Nur Aini Rakhmawati

    2006-01-01

    Full Text Available Normal 0 false false false IN X-NONE X-NONE MicrosoftInternetExplorer4 Berlakunya Undang – undang Hak Atas Kekayaan Intelektual (HAKI, memunculkan suatu alternatif baru untuk menggunakan software open source. Penggunaan software open source menyebar seiring dengan isu global pada Information Communication Technology (ICT saat ini. Beberapa organisasi dan perusahaan mulai menjadikan software open source sebagai pertimbangan. Banyak konsep mengenai software open source ini. Mulai dari software yang gratis sampai software tidak berlisensi. Tidak sepenuhnya isu software open source benar, untuk itu perlu dikenalkan konsep software open source mulai dari sejarah, lisensi dan bagaimana cara memilih lisensi, serta pertimbangan dalam memilih software open source yang ada. Kata kunci :Lisensi, Open Source, HAKI

  18. Essence: Facilitating Software Innovation

    DEFF Research Database (Denmark)

    Aaen, Ivan

    2008-01-01

      This paper suggests ways to facilitate creativity and innovation in software development. The paper applies four perspectives – Product, Project, Process, and People –to identify an outlook for software innovation. The paper then describes a new facility–Software Innovation Research Lab (SIRL......) – and a new method concept for software innovation – Essence – based on views, modes, and team roles. Finally, the paper reports from an early experiment using SIRL and Essence and identifies further research....

  19. Global Software Engineering

    DEFF Research Database (Denmark)

    Ebert, Christof; Kuhrmann, Marco; Prikladnicki, Rafael

    2016-01-01

    Professional software products and IT systems and services today are developed mostly by globally distributed teams, projects, and companies. Successfully orchestrating Global Software Engineering (GSE) has become the major success factor both for organizations and practitioners. Yet, more than...... and experience reported at the IEEE International Conference on Software Engineering (ICGSE) series. The outcomes of our analysis show GSE as a field highly attached to industry and, thus, a considerable share of ICGSE papers address the transfer of Software Engineering concepts and solutions to the global stage...

  20. Improving Software Engineering on NASA Projects

    Science.gov (United States)

    Crumbley, Tim; Kelly, John C.

    2010-01-01

    Software Engineering Initiative: Reduces risk of software failure -Increases mission safety. More predictable software cost estimates and delivery schedules. Smarter buyer of contracted out software. More defects found and removed earlier. Reduces duplication of efforts between projects. Increases ability to meet the challenges of evolving software technology.

  1. Elementary School-Located Influenza Vaccine Programs: Key Stakeholder Experiences from Initiation to Continuation

    Science.gov (United States)

    Williams, Valerie; Rousculp, Matthew D.; Price, Mark; Coles, Theresa; Therrien, Michelle; Griffin, Jane; Hollis, Kelly; Toback, Seth

    2012-01-01

    This study examined the initiation and logistics, funding, perceived barriers and benefits, and disruption of school activities by school-located influenza vaccination (SLIV) programs conducted during the 2008-2009 influenza season. Seventy-two interviews using a structured protocol were conducted with 26 teachers, 16 school administrators, and 30…

  2. Assessment of pain experience in adults and children after bracket bonding and initial archwire insertion

    Directory of Open Access Journals (Sweden)

    Marcio José da Silva Campos

    2013-10-01

    Full Text Available INTRODUCTION: Ninety five percent of orthodontic patients routinely report pain, due to alterations in the periodontal ligament and surrounding soft tissues, with intensity and prevalence varying according to age. OBJECTIVE: This study aimed to assess toothache and buccal mucosal pain in adults and children during two initial phases of the orthodontic treatment. METHODS: The intensity of toothache and buccal mucosal pain reported by 20 patients, 10 children (11-13 years and 10 adults (18-37 years was recorded with the aid of a Visual Analog Scale (VAS, during 14 days - 7 days with bonded brackets only and 7 days with the initial archwire inserted. RESULTS: There was no significant difference in pain intensity among adults and children. After bracket bonding, 50% of the children and 70% of the adults reported pain. 70% of both groups reported pain after initial archwire insertion. While adults reported constant, low intensity, buccal mucosal pain, the children showed great variation of pain intensity, but with a trend towards decreasing pain during the assessment period. After initial archwire insertion the peaks of toothache intensity and prevalence occurred 24 hours in children and 48 hours in adults. CONCLUSIONS: In general, children reported pain less frequently than adults did, though with greater intensity.

  3. State Initiatives for the Empowerment of Women of Rural Communities: Experiences from Eastern India.

    Science.gov (United States)

    Lahiri-Dutt, Kuntala; Samanta, Gopa

    2002-01-01

    Discussions with women in rural areas of India analyzed government-initiated development programs regarding availability of information, suitability to women's needs, and perception of problems. Most programs were top down with little input form women; self-help approaches problematized the "self" and did not consider the realities of…

  4. Robotics in hepatobiliary surgery-initial experience, first reported case series from India

    Directory of Open Access Journals (Sweden)

    S. Goja

    2017-01-01

    Conclusion: This initial series adds to existing data on the feasibility of robotic hepatobiliary cases with inherent advantages of minimal invasive surgery, however with limitation of availability and use of devices like cavitron ultrasonic surgical aspirator (CUSA and higher operative cost.

  5. Black Male Retention Initiatives: Exploring Students' Experiences and Program Effectiveness at Predominantly White Institutions

    Science.gov (United States)

    St. Leger, Gabrielle

    2012-01-01

    Recent initiatives in higher education have been designed to increase Black undergraduate male collegiate retention and persistence through graduation for this historically underrepresented population. Although institutional leaders in higher education have focused on creating more inclusive campuses, designing and implementing programs to retain…

  6. Software Metrics and Software Metrology

    CERN Document Server

    Abran, Alain

    2010-01-01

    Most of the software measures currently proposed to the industry bring few real benefits to either software managers or developers. This book looks at the classical metrology concepts from science and engineering, using them as criteria to propose an approach to analyze the design of current software measures and then design new software measures (illustrated with the design of a software measure that has been adopted as an ISO measurement standard). The book includes several case studies analyzing strengths and weaknesses of some of the software measures most often quoted. It is meant for sof

  7. Signature Visualization of Software Binaries

    Energy Technology Data Exchange (ETDEWEB)

    Panas, T

    2008-07-01

    In this paper we present work on the visualization of software binaries. In particular, we utilize ROSE, an open source compiler infrastructure, to pre-process software binaries, and we apply a landscape metaphor to visualize the signature of each binary (malware). We define the signature of a binary as a metric-based layout of the functions contained in the binary. In our initial experiment, we visualize the signatures of a series of computer worms that all originate from the same line. These visualizations are useful for a number of reasons. First, the images reveal how the archetype has evolved over a series of versions of one worm. Second, one can see the distinct changes between version. This allows the viewer to form conclusions about the development cycle of a particular worm.

  8. ONR Tropical Cyclone Motion Research Initiative: Data Assimilation Considerations for Field Experiment Analyses

    Science.gov (United States)

    1989-09-01

    Australian Bureau of Meteorology 33 Research Centre Regional Data Assimilation System Appendix E: Brief Description of the Global Analysis and Forecast 39...participants. Comparable descriptions were prepared by the Australian Bureau of Meteorology (Appendix 1)), Japan Meteorological Agency (Appendix E...the operational regional models at Bureau of Meteorology and FNOC, a vertical normal mode initialization is used. Only a few (say, three or four

  9. Role of radiology in a national initiative to interdict drug smuggling: the Dutch experience.

    Science.gov (United States)

    Algra, Paul R; Brogdon, Byron G; Marugg, Roque C

    2007-08-01

    The purpose of this pictorial essay is to describe the role of radiology in a national initiative to intercept illegal narcotics concealed within the bodies of human transporters. Radiologic examination is increasingly important in identifying intracorporeal drug smuggling as improved wrapping techniques undermine the usefulness of blood and urine testing and clinical observation. Detection rates of high accuracy, sensitivity, and specificity are achieved by experienced radiologists.

  10. Software reliability

    CERN Document Server

    Bendell, A

    1986-01-01

    Software Reliability reviews some fundamental issues of software reliability as well as the techniques, models, and metrics used to predict the reliability of software. Topics covered include fault avoidance, fault removal, and fault tolerance, along with statistical methods for the objective assessment of predictive accuracy. Development cost models and life-cycle cost models are also discussed. This book is divided into eight sections and begins with a chapter on adaptive modeling used to predict software reliability, followed by a discussion on failure rate in software reliability growth mo

  11. Scrapie infections initiated at varying doses: an analysis of 117 titration experiments.

    Science.gov (United States)

    McLean, A R; Bostock, C J

    2000-08-29

    An analysis of 117 titration experiments in the murine scrapie model is presented. The experiments encompass 30 years' work and a wide range of experimental conditions. To check that the experimental designs were reasonably consistent over time, comparisons were made of size, duration, source of inoculum, etc., in each experiment. These comparisons revealed no systematic trends that would render invalid comparisons across experiments. For 114 of the experiments it was possible to calculate the dose at which half of the challenged animals were infected (the ID50). These 114 experiments were then combined on the basis of relative dose (i.e. tenfold dilution relative to the ID50). This created a data set in which over 4000 animals were challenged with doses of scrapie ranging from four orders of magnitude below to five orders of magnitude above the ID50. Analysis of this data reveals that mean incubation periods rise linearly with logarithmic decreases in dose. A one unit increase in relative dose (i.e. a tenfold increase in actual dose) will, on average, decrease the incubation period by 25 days. At ID50 the average incubation period in this data set is 300 days. Within a single dose, in a single experimental model, incubation periods have a distribution close to normal. Variability in incubation period also rises linearly as dose decreases. There is no age or sex effect upon the probability of infection, but female mice have incubation periods that are, on average, nine days shorter than their male counterparts and young mice have incubation periods that are longer by seven days. Although many of these patterns are apparent in the results of single titration curves, they can be more rigorously investigated by considering the outcome for thousands of mice.

  12. To Explore the Experiences of Women on Reasons in Initiating and Maintaining Breastfeeding in Urban Area of Karachi, Pakistan: An Exploratory Study

    OpenAIRE

    Zahra Shaheen Premani; Zohra Kurji; Yasmin Mithani

    2011-01-01

    This is an exploratory study that explores the experiences of lactating women in initiating, continuing, or discontinuing breastfeeding in an urban area of Karachi, Pakistan. Objectives. To explore the experiences of lactating women and to understand their support and hindering mechanisms in initiating and maintaining breastfeeding. Methods. This is an exploratory design assisting in exploring the participant's experiences of initiating and maintaining breastfeeding to better understand their...

  13. Clinical experience with Mobius FX software for 3D dose verification for prostate VMAT plans and comparison with physical measurements

    Science.gov (United States)

    Vazquez-Quino, L. A.; Huerta-Hernandez, C. I.; Rangaraj, D.

    2017-05-01

    MobiusFX, an add-on software module from Mobius Medical Systems for IMRT and VMAT QA, uses measurements in linac treatment logs to calculate and verify the 3D dose delivered to patients. In this study, 10 volumetric-modulated arc therapy (VMAT) prostate plans were planned and delivered in a Varian TrueBeam linac. The plans consisted of beams with 6 and 10 MV energy and 2 to 3 arcs per plan. The average gamma value with criterion of 3% and 3mm MobiusFX and TPS: 99.96%, 2% and 2mm MobiusFX and TPS: 98.70 %. Further comparison with ArcCheck measurements was conducted.

  14. Initial Clinical Experience With Surgical Technique of Robot-assisted Transperitoneal Laparoscopic Partial Nephrectomy

    Directory of Open Access Journals (Sweden)

    Cheng-Kuang Yang

    2009-12-01

    Conclusion: Robot-assisted LPN is feasible and may be a viable alternative to open or LPN in selected patients with small exophytic renal tumors. Compared with standard LPN, the robotic assisted LPN approach with precise renal reconstruction under a safe warm ischemia time is feasible and can be easily adopted by those with experience in robot-assisted surgery.

  15. Initial experience with transperitoneal laparoscopic nephrectomy in an Irish hospital setting.

    LENUS (Irish Health Repository)

    Forde, J C

    2009-08-01

    Laparoscopic nephrectomy has gained widespread acceptance as a treatment for both benign and malignant conditions and is becoming increasingly popular in Irish hospitals. We report a single surgeon, single centre experience with 20 consecutive laparoscopic nephrectomies comparing them to 20 open cases performed prior to the establishment of a laparoscopic service.

  16. CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells

    Directory of Open Access Journals (Sweden)

    Karen G. Wong

    2017-07-01

    Full Text Available Human pluripotent stem cells (PSCs provide an unlimited cell source for cell therapies and disease modeling. Despite their enormous power, technical aspects have hampered reproducibility. Here, we describe a modification of PSC workflows that eliminates a major variable for nearly all PSC experiments: the quality and quantity of the PSC starting material. Most labs continually passage PSCs and use small quantities after expansion, but the “just-in-time” nature of these experiments means that quality control rarely happens before use. Lack of quality control could compromise PSC quality, sterility, and genetic integrity, which creates a variable that might affect results. This method, called CryoPause, banks PSCs as single-use, cryopreserved vials that can be thawed and immediately used in experiments. Each CryoPause bank provides a consistent source of PSCs that can be pre-validated before use to reduce the possibility that high levels of spontaneous differentiation, contamination, or genetic integrity will compromise an experiment.

  17. Investigating the Impact of Mediated Learning Experiences on Cooperative Peer Communication during Group Initiatives

    Science.gov (United States)

    White, Robert; Dinos, Sokratis

    2010-01-01

    This study investigates how structured Mediated Learning Experiences may improve peer-cooperative communication within problem-solving task exercises. Two groups (n = 22) of Year 8 students (mean age 13 +/- 5 months) were randomly selected to participate in this study. The study began with two one-hour sessions of activity-based problem-solving…

  18. Teachers' Experiences of a Single-Sex Initiative in a Co-Education School

    Science.gov (United States)

    Gray, Colette; Wilson, Joanne

    2006-01-01

    Argued to "raise boys' grades" and "boost boys' academic achievement", single-sex classes in coeducation schools is one strategy among a plethora aimed at raising standards. This paper explores the experiences of teachers in one coeducation post-primary school that sought to raise academic performance, particularly among boys,…

  19. Experiences of Student Speech-Language Pathology Clinicians in the Initial Clinical Practicum: A Phenomenological Study

    Science.gov (United States)

    Nelson, Lori A.

    2011-01-01

    Speech-language pathology literature is limited in describing the clinical practicum process from the student perspective. Much of the supervision literature in this field focuses on quantitative research and/or the point of view of the supervisor. Understanding the student experience serves to enhance the quality of clinical supervision. Of…

  20. The Architecture of a Software System for Supporting Community-based Primary Health Care with Mobile Technology: The Mobile Technology for Community Health (MoTeCH) Initiative in Ghana.

    Science.gov (United States)

    Macleod, Bruce; Phillips, James; Stone, Allison E; Walji, Aliya; Awoonor-Williams, John Koku

    2012-01-01

    THIS PAPER DESCRIBES THE SOFTWARE ARCHITECTURE OF A SYSTEM DESIGNED IN RESPONSE TO THE HEALTH DEVELOPMENT POTENTIAL OF TWO CONCOMITANT TRENDS IN POOR COUNTRIES: i) The rapid expansion of community health worker deployment, now estimated to involve over a million workers in Africa and Asia, and ii) the global proliferation of mobile technology coverage and use. Known as the Mobile Technology for Community Health (MoTeCH) Initiative, our system adapts and integrates existing software applications for mobile data collection, electronic medical records, and interactive voice response to bridge health information gaps in rural Africa. MoTeCH calculates the upcoming schedule of care for each client and, when care is due, notifies the client and community health workers responsible for that client. MoTeCH also automates the aggregation of health status and health service delivery information for routine reports. The paper concludes with a summary of lessons learned and future system development needs.

  1. Assessment of crown fire initiation and spread models in Mediterranean conifer forests by using data from field and laboratory experiments

    Energy Technology Data Exchange (ETDEWEB)

    Rodríguez y Silva, F.; Guijarro, M.; Madrigal, J.; Jiménez, E.; Molina, J.R.; Hernando, C.; Vélez, R.; Vega, J.A.

    2017-11-01

    Aims of study: To conduct the first full-scale crown fire experiment carried out in a Mediterranean conifer stand in Spain; to use different data sources to assess crown fire initiation and spread models, and to evaluate the role of convection in crown fire initiation. Area of study: The Sierra Morena mountains (Coordinates ETRS89 30N: X: 284793-285038; Y: 4218650-4218766), southern Spain, and the outdoor facilities of the Lourizán Forest Research Centre, northwestern Spain. Material and methods: The full-scale crown fire experiment was conducted in a young Pinus pinea stand. Field data were compared with data predicted using the most used crown fire spread models. A small-scale experiment was developed with Pinus pinaster trees to evaluate the role of convection in crown fire initiation. Mass loss calorimeter tests were conducted with P. pinea needles to estimate residence time of the flame, which was used to validate the crown fire spread model. Main results: The commonly used crown fire models underestimated the crown fire spread rate observed in the full-scale experiment, but the proposed new integrated approach yielded better fits. Without wind-forced convection, tree crowns did not ignite until flames from an intense surface fire contacted tree foliage. Bench-scale tests based on radiation heat flux therefore offer a limited insight to full-scale phenomena. Research highlights: Existing crown fire behaviour models may underestimate the rate of spread of crown fires in many Mediterranean ecosystems. New bench-scale methods based on flame buoyancy and more crown field experiments allowing detailed measurements of fire behaviour are needed.

  2. Initiating informatics and GIS support for a field investigation of Bioterrorism: The New Jersey anthrax experience

    Directory of Open Access Journals (Sweden)

    Skinner Ric

    2003-11-01

    Full Text Available Abstract Background The investigation of potential exposure to anthrax spores in a Trenton, New Jersey, mail-processing facility required rapid assessment of informatics needs and adaptation of existing informatics tools to new physical and information-processing environments. Because the affected building and its computers were closed down, data to list potentially exposed persons and map building floor plans were unavailable from the primary source. Results Controlling the effects of anthrax contamination required identification and follow-up of potentially exposed persons. Risk of exposure had to be estimated from the geographic relationship between work history and environmental sample sites within the contaminated facility. To assist in establishing geographic relationships, floor plan maps of the postal facility were constructed in ArcView Geographic Information System (GIS software and linked to a database of personnel and visitors using Epi Info and Epi Map 2000. A repository for maintaining the latest versions of various documents was set up using Web page hyperlinks. Conclusions During public health emergencies, such as bioterrorist attacks and disease epidemics, computerized information systems for data management, analysis, and communication may be needed within hours of beginning the investigation. Available sources of data and output requirements of the system may be changed frequently during the course of the investigation. Integrating data from a variety of sources may require entering or importing data from a variety of digital and paper formats. Spatial representation of data is particularly valuable for assessing environmental exposure. Written documents, guidelines, and memos important to the epidemic were frequently revised. In this investigation, a database was operational on the second day and the GIS component during the second week of the investigation.

  3. Systematic Software Development

    DEFF Research Database (Denmark)

    Kuhrmann, Marco; Méndez Fernández, Daniel

    2015-01-01

    makes these countries an attractive host for software companies. Often, high-quality engineering and excellent quality of products, e.g., machinery and equipment, are mentioned. Yet, the question is: Can such arguments be also found for the software industry? We aim at investigating the degree...... project- and quality management and their implementation in practice. So far, our results suggest that the necessity for a systematic software development is well recognized, while software development still follows an ad-hoc rather than a systematized style. Our results provide initial findings, which we......The speed of innovation and the global allocation of resources to accelerate development or to reduce cost put pressure on the software industry. In the global competition, especially so-called high-price countries have to present arguments why the higher development cost is justified and what...

  4. Initial Smoking Experiences and Current Smoking Behaviors and Perceptions among Current Smokers.

    Science.gov (United States)

    Klein, Hugh; Sterk, Claire E; Elifson, Kirk W

    2013-01-01

    Purpose. We examine early-onset cigarette smoking and how, if at all, it is related to subsequent smoking practices. Methods. From 2004 to 2007, face-to-face interviews were conducted with 485 adult cigarette smokers residing in the Atlanta metropolitan area. Data analysis involved a multivariate analysis to determine whether age of smoking onset was related to current smoking practices when the effects of gender, age, race, marital/relationship status, income, and educational attainment were taken into account. Results. The mean age for smoking onset was 14.8, and more than one-half of all smokers had their first cigarette between the ages of 12 and 16. Most people reported an interval of less than one month between their first and second time using tobacco. Earlier onset cigarette smoking was related to more cigarette use and worse tobacco-related health outcomes in adulthood. Conclusions. Early prevention and intervention are needed to avoid early-onset smoking behaviors. Intervening after initial experimentation but before patterned smoking practices are established will be challenging, as the interval between initial and subsequent use tends to be short.

  5. Initial Smoking Experiences and Current Smoking Behaviors and Perceptions among Current Smokers

    Directory of Open Access Journals (Sweden)

    Hugh Klein

    2013-01-01

    Full Text Available Purpose. We examine early-onset cigarette smoking and how, if at all, it is related to subsequent smoking practices. Methods. From 2004 to 2007, face-to-face interviews were conducted with 485 adult cigarette smokers residing in the Atlanta metropolitan area. Data analysis involved a multivariate analysis to determine whether age of smoking onset was related to current smoking practices when the effects of gender, age, race, marital/relationship status, income, and educational attainment were taken into account. Results. The mean age for smoking onset was 14.8, and more than one-half of all smokers had their first cigarette between the ages of 12 and 16. Most people reported an interval of less than one month between their first and second time using tobacco. Earlier onset cigarette smoking was related to more cigarette use and worse tobacco-related health outcomes in adulthood. Conclusions. Early prevention and intervention are needed to avoid early-onset smoking behaviors. Intervening after initial experimentation but before patterned smoking practices are established will be challenging, as the interval between initial and subsequent use tends to be short.

  6. The Accelerating Access Initiative: experience with a multinational workplace programme in Africa.

    Science.gov (United States)

    Van der Borght, S; Janssens, V; Schim van der Loeff, M F; Kajemba, A; Rijckborst, H; Lange, J M A; Rinke de Wit, T F

    2009-10-01

    A multinational company with operations in several African countries was committed to offer antiretroviral treatment to its employees and their dependants. The Accelerating Access Initiative (AAI), an initiative of six pharmaceutical companies and five United Nations' agencies, offered the possibility of obtaining brand antiretroviral drugs (ARVs) at 10% of the commercial price. PharmAccess, a foundation aimed at removing barriers to AIDS treatment in Africa, helped to establish an HIV policy and treatment guidelines, and a workplace programme was rolled out from September 2001. Private sector employers in Africa are keen to take more responsibility in HIV prevention and AIDS care. An important hurdle for African employers remains the price and availability of ARVs. The programme encountered various hurdles, among them the need for multiple contracts with multiple companies, complex importation procedures, taxes levied on ARVs, lack of support from pharmaceutical companies in importation and transportation, slow delivery of the drugs, lack of institutional memory in pharmaceutical companies and government policies excluding the company from access to ARVs under the AAI. The launch of the AAI enabled this multinational company to offer access to ARVs to its employees and dependants. The private sector should have access to these discounted drugs under the AAI. A network of local AAI offices should be created to assist in logistics of drugs ordering, purchase and clearance. No taxes should be levied on ARVs.

  7. Initial 10-year Experience of Sperm Cryopreservation Services for Cancer Patients

    Directory of Open Access Journals (Sweden)

    Hong-Chiang Chang

    2006-01-01

    Full Text Available Offering sperm cryopreservation to preserve the fertility of male cancer patients is a relatively recent service in Asia. This study analyzed the types of cancer, timing of collection, sperm quality, and utilization for reproductive services by patients during a 10-year period at a medical center in Taiwan. A total of 75 oncology patients elected to freeze sperm for fertility preservation at our medical center during the initial 10 years of the availability of this service. The mean age of the patients was 25.7 years. Storage was discontinued in 13 (17% patients and their survival duration was 13.1 ±11.1 months. The utilization rate of sperm cryo-preservation was 2.8% (75/2642. The types of cancer varied, with leukemia (35%, lymphoma (25%, and testicular cancer (13% comprising the largest groups. A significantly lower sperm count was found in patients with chronic myelogenous leukemia, suggesting the need for earlier sperm collection after initiation of cancer treatment. Only three (4% patients utilized their specimens for reproductive purposes. There was no clinical pregnancy during the study period, although one biochemical pregnancy was achieved. The low rates of sperm cryostorage for fertility preservation in cancer patients in this study suggest that there is a need for greater emphasis of this option for male oncology patients whose fertility is likely to be affected by chemotherapeutic treatment.

  8. Role of laser myringotomy in a pediatric otolaryngology practice: initial experience

    Science.gov (United States)

    Shah, Udayan K.

    2001-05-01

    A new technology (OtoLAM) to fenestrate the tympanic membrane with the carbon dioxide laser (CO2), in the office or the operating room, has been introduced over the last three years. While not new conceptually, this product offers the ability to easily create a precise window into the middle ear using a portable system. Controversy regarding the indications and benefits of this technique, amplified by the costs of the system and the marketing of the technology prior to extensive clinical testing, has plagued the clinical application of this technology. We report our experience over the past year with this system in a busy pediatric otolaryngology practice. Laser fenestration of the tympanic membrane has been useful for the insertion of tympanostomy tubes, and for the minimally invasive evaluation of the middle ear. Our small experience to date reveals that there is a limited role for laser tympanic membrane fenestration in a busy pediatric otolaryngology practice.

  9. Initial performance of the radio occultation experiment in the Venus orbiter mission Akatsuki

    Science.gov (United States)

    Imamura, Takeshi; Ando, Hiroki; Tellmann, Silvia; Pätzold, Martin; Häusler, Bernd; Yamazaki, Atsushi; Sato, Takao M.; Noguchi, Katsuyuki; Futaana, Yoshifumi; Oschlisniok, Janusz; Limaye, Sanjay; Choudhary, R. K.; Murata, Yasuhiro; Takeuchi, Hiroshi; Hirose, Chikako; Ichikawa, Tsutomu; Toda, Tomoaki; Tomiki, Atsushi; Abe, Takumi; Yamamoto, Zen-ichi; Noda, Hirotomo; Iwata, Takahiro; Murakami, Shin-ya; Satoh, Takehiko; Fukuhara, Tetsuya; Ogohara, Kazunori; Sugiyama, Ko-ichiro; Kashimura, Hiroki; Ohtsuki, Shoko; Takagi, Seiko; Yamamoto, Yukio; Hirata, Naru; Hashimoto, George L.; Yamada, Manabu; Suzuki, Makoto; Ishii, Nobuaki; Hayashiyama, Tomoko; Lee, Yeon Joo; Nakamura, Masato

    2017-10-01

    After the arrival of Akatsuki spacecraft of Japan Aerospace Exploration Agency at Venus in December 2015, the radio occultation experiment, termed RS (Radio Science), obtained 19 vertical profiles of the Venusian atmosphere by April 2017. An onboard ultra-stable oscillator is used to generate stable X-band downlink signals needed for the experiment. The quantities to be retrieved are the atmospheric pressure, the temperature, the sulfuric acid vapor mixing ratio, and the electron density. Temperature profiles were successfully obtained down to 38 km altitude and show distinct atmospheric structures depending on the altitude. The overall structure is close to the previous observations, suggesting a remarkable stability of the thermal structure. Local time-dependent features are seen within and above the clouds, which is located around 48-70 km altitude. The H2SO4 vapor density roughly follows the saturation curve at cloud heights, suggesting equilibrium with cloud particles. The ionospheric electron density profiles are also successfully retrieved, showing distinct local time dependence. Akatsuki RS mainly probes the low and middle latitude regions thanks to the near-equatorial orbit in contrast to the previous radio occultation experiments using polar orbiters. Studies based on combined analyses of RS and optical imaging data are ongoing.[Figure not available: see fulltext.

  10. Shock Initiation Behavior of PBXN-9 Determined by Gas Gun Experiments

    Science.gov (United States)

    Sanchez, N. J.; Gustavsen, R. L.; Hooks, D. E.

    2009-12-01

    The shock to detonation transition was evaluated in the HMX based explosive PBXN-9 by a series of light-gas gun experiments. PBXN-9 consists of 92 wt% HMX, 2wt% Hycar 4054 & 6 wt&percent; dioctyl adipate with a density of 1.75 g/cm3 and 0.8&% voids. The experiments were designed to understand the specifics of wave evolution and the run distance to detonation as a function of input shock pressure. These experiments were conducted on gas guns in order to vary the input shock pressure accurately. The primary diagnostics were embedded magnetic gauges, which are based on Faraday's law of induction, and Photon Doppler Velocimetry (PDV). The run distance to detonation vs. shock pressure, or "Pop plot," was redefined as log(X) = 2.14-1.82 log (P), which is substantially different than previous data. The Hugoniot was refined as Us = 2.32+2.211 Up. This data will be useful for the development of predictive models for the safety and performance of PBXN-9 along with providing increased understanding of HMX based explosives in varying formulations.

  11. Guide to software export

    CERN Document Server

    Philips, Roger A

    2014-01-01

    An ideal reference source for CEOs, marketing and sales managers, sales consultants, and students of international marketing, Guide to Software Export provides a step-by-step approach to initiating or expanding international software sales. It teaches you how to examine critically your candidate product for exportability; how to find distributors, agents, and resellers abroad; how to identify the best distribution structure for export; and much, much more!Not content with providing just the guidelines for setting up, expanding, and managing your international sales channels, Guide to Software

  12. Initial operation and performance projections for the Lithium Tokamak eXperiment (LTX)

    Science.gov (United States)

    Majeski, R.; Berzak, L.; Gray, T.; Kaita, R.; Kozub, T.; Lundberg, D. P.; Manickam, J.; Snieckus, K.; Stotler, D.; Strickler, T.; Timberlake, J.; Yoo, J.; Zakharov, L.; Ellison, C. L.; Pereverzev, G. V.; Soukhanovskii, V.

    2008-11-01

    LTX is a modest-sized spherical tokamak with R=0.4 m, a=0.26 m, κ=1.5, Btoroidal 50 msec. First plasma is expected in September 2008. The research objective is to investigate modifications to equilibria and transport when global recycling is reduced to very low values (film. Initial operation will utilize a reduced Ohmic power supply, and lithium will not be introduced into the device until trials of all systems are successfully completed. The device itself, early discharges, and performance projections using the ASTRA simulation code will be discussed. MHD stability with a very close, conducting, conformal wall is also briefly discussed (see poster by J. Manickam). Diagnostics are discussed in companion posters by L. Berzak, D. Lundberg, and T. Strickler.

  13. Hydrothermal ceramic for porcelain-fused-to-metal crowns: an initial experience report from clinical practice.

    Science.gov (United States)

    Mattmüller, A; Wassmann, J; Biffar, R

    1996-08-01

    The development of hydrothermal ceramics was an important requirement for fusing hydrolysis-resistant ceramics to precious metal alloys with low melting interval. Clinical findings since 1992 confirm the wide range of application of these metal-ceramic restorations in dentistry. Initial problems concerning temperature regulation of the ceramic ovens were rectified by checking and adjusting them for lower sintering temperatures. The golden yellow color is only one advantage of the ceramic-veneered alloy. Other advantages include its nonporous, smooth surface, translucence, and suitability for use in all types of dental restorations and reconstructions. Hydrothermal ceramic veneers thus can help to substantially reduce the number of different alloys used in a patient's mouth.

  14. Antimicrobial Resistance Control Strategies: A Coordinated Research Initiative Experience in the Asia Pacific Region.

    Science.gov (United States)

    Lapierre, Lisette; Asenjo, Gabriela; Vergara, Constanza; Cornejo, Javiera

    2017-05-01

    The objective was to gather information on the status of antimicrobial surveillance in the Asia Pacific region and suggest control strategies. Twenty-one economies of the Asia Pacific region participated in this initiative. A survey was conducted on antimicrobial use and surveillance throughout the region. A workshop was carried out to create awareness about the issue and discuss the implementation of control strategies. Based on the survey results and workshop conclusions, it can be established that there is better understanding of the implications of antimicrobial resistance in the human medicine area. Only few economies take actions to control antimicrobial resistance on a veterinary/agricultural level. To confront antimicrobial resistance, it is critical to raise awareness; cooperation between all countries is needed to apply international standards, to be able to have harmonized public policies. Countries must align and improve their systems for surveillance and monitoring of antimicrobial resistance in human, animals, and the environment.

  15. Upgrading the Interface and Developer Tools of the Trigger Supervisor Software Framework of the CMS experiment at CERN

    CERN Document Server

    AUTHOR|(CDS)2097518; Karsmakers, Peter

    The Compact Muon Solenoid (CMS) Trigger Supervisor (TS) is a software framework that has been designed to handle the CMS Level-1 trigger setup, configuration and monitoring during data taking as well as all communications with the main run control of CMS. The interface consists of a web-based GUI rendered by a back-end C++ framework (AjaXell) and a front-end JavaScript framework (Dojo). These provide developers with the tools they need to to write their own custom control panels. However, currently there is much frustration with this framework given the age of the Dojo library and the various hacks needed to implement modern use cases. The task at hand is to renew this library and its developer tools, updating it to use the newest standards and technologies, while maintaining full compatibility with legacy code. This document describes the requirements, development process, and changes to this framework that were included in the upgrade from v2.x to v3.x. Keywords: CERN, CMS, L1 Trigger, C++, Polymer, Web Com...

  16. FREND experiment on ESA's TGO mission: science tasks, initial space data and expected results

    Science.gov (United States)

    Mitrofanov, Igor; Malakhov, Aleksey; Golovin, Dmitry; Litvak, Maxim; Sanin, Anton; Semkova, Jordanka

    2017-04-01

    The main science tasks are presented in details of the Fine Resolution Epithermal Neutron Detector (FREND) onboard the ESA's Trace Gas Orbiter (TGO). They are (I) mapping of water distribution in the shallow subsurface of Mars with the special resolution about 40 km, (II) measuring of the seasonal depositions of atmospheric carbon dioxide on the southern and northern hemispheres of Mars, and (III) monitoring of galactic cosmic rays (GCRs) and solar particle events (SPEs) on the low Mars orbit. The initial science data of FREND are described measured during the interplanetary cruise and at the initial stage of the orbital flight. These data allow to estimate the local radiation environment of TGO, which is produced by GCRs, and also the neutron albedo of the Mars surface, which is also produced by the bombardment by GCRs. Using the first FREND space data for in-space calibration, the background components are estimated for the future low-orbit mapping of neutrons from Mars. Using the first experimental data, expected science results of FREND are discussed. It is shown that joint analysis of the orbital neutron data from FREND onboard the TGO, the orbital neutron data from HEND onboard the Mars Odyssey and the surface neutron data from DAN onboard the Curiosity rover should allow to characterize the ground water/ice distribution on the surface of Mars and also to build the seasonal maps of atmospheric CO2 depositions for different intervals of Ls. Special and temporal variations of the Martian radiation environment should be measured as well. Finally, the most ambitious goal of the TGO multi-instrument studies could be testing the cross-correspondence between the water-rich spots on the surface with the local enhancements of methane in the atmosphere

  17. Initial Thomson Scattering Survey of Local Helicity Injection and Ohmic Plasmas at the Pegasus Toroidal Experiment

    Science.gov (United States)

    Schlossberg, D. J.; Bodner, G. M.; Bongard, M. W.; Fonck, R. J.; Winz, G. R.

    2014-10-01

    A multipoint Thomson scattering diagnostic has recently been installed on the Pegasus ST. The system utilizes a frequency-doubled Nd:YAG laser (λ0 ~ 532 nm), spectrometers with volume phase holographic gratings, and a gated, intensified CCD camera. It provides measurements of Te and ne at 8 spatial locations for each spectrometer once per discharge. A new multiple aperture and beam dump system has been implemented to mitigate interference from stray light. This system has provided initial measurements in the core region of plasmas initiated by local helicity injection (LHI), as well as conventional Ohmic L- and H-mode discharges. Multi-shot averages of low-density (ne ~ 3 ×1018 m-3) , Ip ~ 0 . 1 MA LHI discharges show central Te ~ 75 eV at the end of the helicity injection phase. Ip ~ 0 . 13 MA Ohmic plasmas at moderate densities (ne ~ 2 ×1019 m-3) have core Te ~ 150 eV in L-mode. Generally, these plasmas do not reach transport equilibrium in the short 25 ms pulse length available. After an L-H transition, strong spectral broadening indicates increasing Te, to values above the range of the present spectrometer system with a high-dispersion VPH grating. Near-term system upgrades will focus on deploying a second spectrometer, with a lower-dispersion grating capable of measuring the 0.1-1.0 keV range. The second spectrometer system will also increase the available number of spatial channels, enabling study of H-mode pedestal structure. Work supported by US DOE Grant DE-FG02-96ER54375.

  18. SU-E-E-05: Initial Experience On Physics Rotation of Radiological Residents

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, J; Williams, D; DiSantis, D; Hardy, P; Oates, M [University of Kentucky, Lexington, KY (United States)

    2014-06-01

    Purpose: The new ABR core exam integrates physics into clinical teaching, with an emphasis on understanding image quality, image artifacts, radiation dose and patient safety for each modality and/or sub-specialty. Accordingly, physics training of radiological residents faces a challenge. A traditional teaching of physics through didactic lectures may not fully fulfill this goal. It is also difficult to incorporate physics teaching in clinical practice due to time constraints. A dedicated physics rotation may be a solution. This study is to evaluate a full week physics workshop developed for the first year radiological residents. Methods: The physics rotation took a full week. It included three major parts, introduction lectures, hand-on experiences and observation of technologist operation. An introduction of basic concepts was given to each modality at the beginning. Hand-on experiments were emphasized and took most of time. During hand-on experiments, residents performed radiation measurements, studied the relationship between patient dose and practice (i.e., fluoroscopy), investigated influence of acquisition parameters (i.g., kV, mAs) on image quality, and evaluated image quality using phantoms A physics test before and after the workshop was also given but not for comparison purpose. Results: The evaluation shows that the physics rotation during the first week of residency in radiology is preferred by all residents. The length of a full week of physics workshop is appropriate. All residents think that the intensive workshop can significantly benefit their coming clinical rotations. Residents become more comfortable regarding the use of radiation and counseling relevant questions such as a pregnant patient risk from a CE PE examination. Conclusion: A dedicated physics rotation, assisting with didactic lectures, may fulfill the requirements of physics of the new ABR core exam. It helps radiologists deeply understand the physics concepts and more efficiently use

  19. Conceptual design of initial opacity experiments on the national ignition facility

    Science.gov (United States)

    Heeter, R. F.; Bailey, J. E.; Craxton, R. S.; Devolder, B. G.; Dodd, E. S.; Garcia, E. M.; Huffman, E. J.; Iglesias, C. A.; King, J. A.; Kline, J. L.; Liedahl, D. A.; McKenty, P. W.; Opachich, Y. P.; Rochau, G. A.; Ross, P. W.; Schneider, M. B.; Sherrill, M. E.; Wilson, B. G.; Zhang, R.; Perry, T. S.

    2017-02-01

    Accurate models of X-ray absorption and re-emission in partly stripped ions are necessary to calculate the structure of stars, the performance of hohlraums for inertial confinement fusion and many other systems in high-energy-density plasma physics. Despite theoretical progress, a persistent discrepancy exists with recent experiments at the Sandia Z facility studying iron in conditions characteristic of the solar radiative-convective transition region. The increased iron opacity measured at Z could help resolve a longstanding issue with the standard solar model, but requires a radical departure for opacity theory. To replicate the Z measurements, an opacity experiment has been designed for the National Facility (NIF). The design uses established techniques scaled to NIF. A laser-heated hohlraum will produce X-ray-heated uniform iron plasmas in local thermodynamic equilibrium (LTE) at temperatures eV and electron densities 21~\\text{cm}-3$ . The iron will be probed using continuum X-rays emitted in a ps, diameter source from a 2 mm diameter polystyrene (CH) capsule implosion. In this design, of the NIF beams deliver 500 kJ to the mm diameter hohlraum, and the remaining directly drive the CH capsule with 200 kJ. Calculations indicate this capsule backlighter should outshine the iron sample, delivering a point-projection transmission opacity measurement to a time-integrated X-ray spectrometer viewing down the hohlraum axis. Preliminary experiments to develop the backlighter and hohlraum are underway, informing simulated measurements to guide the final design.

  20. Initial psychoacoustic experiments on the human response to transmission line audible noise

    Energy Technology Data Exchange (ETDEWEB)

    Molino, J.A.; Zerdy, G.A.; Lerner, N.D.; Harwood, D.L.; Tremaine, S.G.

    1978-01-01

    A project is underway to investigate human response to transmission line audible noise. This project is developing a psychoacoustic data-base to determine the extent to which present measurement scales and human response criteria are appropriate for evaluating the environmental impact of transmission line audible noise, and to suggest different scales and criteria if necessary. A realistic listening room was used for psychoacoustic experiments in which a listener was given choices between various acoustic environments, including corona sounds, while reading a book. In another experiment groups of participants rated various sounds for their annoyance level while watching television programs. Results indicate that despite its relatively low sound level, corona noise is equally aversive to certain other environmental sounds that are 8 dB higher in sound pressure level. All of the common frequency weighting scales underestimate the aversiveness of corona noise relative to other environmental sounds. From a limited sample of comparison sounds, corona noise was found to be roughly equal in aversiveness to the noise from a room air conditioner. Knowledge of the source of the noise did not affect the relative aversiveness of corona noise as presented in the laboratory. The high-frequency hissing and crackling components of corona noise are more aversive than the low-frequency humming and buzzing components. There are distinctly different kinds of corona noise which differ both in frequency spectrum and relative aversiveness. Thus, in order to assess environmental impact, long-term sampling of corona noise from different lines may be needed. Similar results were obtained from experiments involving reading and television viewing as participant activities, indicating consistent and generalizable findings. (JGB)

  1. Using Educational Games and Simulation Software in a Computer Science Course: Learning Achievements and Student Flow Experiences

    Science.gov (United States)

    Liu, Tsung-Yu

    2016-01-01

    This study investigates how educational games impact on students' academic performance and multimedia flow experiences in a computer science course. A curriculum consists of five basic learning units, that is, the stack, queue, sort, tree traversal, and binary search tree, was conducted for 110 university students during one semester. Two groups…

  2. Toward Improving Transurethral Prostate Surgery: Development and Initial Experiments with a Prototype Concentric Tube Robotic Platform.

    Science.gov (United States)

    Mitchell, Christopher R; Hendrick, Richard J; Webster, Robert J; Herrell, S Duke

    2016-06-01

    Despite the potential clinical advantages of holmium laser enucleation of the prostate (HoLEP), there has been reluctance of the urologic community to adopt the procedure, as a result of a perceived steep learning curve. Thus, we sought to design and develop a transurethral endoscopic robotic platform for HoLEP. We developed a novel transurethral, concentric tube robotic platform for HoLEP. We conducted magnetic tracking experiments to compare movements of the end effectors of the robot with those of a rigid endoscope. Additionally, we tested the robot on an HoLEP simulator and with a human cadaveric prostate to assess its ability to maneuver within a small working space. In the prostate scanning experiment, the area reached by the robot represents a 65% improvement vs the area accessible by a rigid endoscope without tissue deformation. Additionally, the robot performed well within the confines of the prostatic urethra and was able to successfully complete prostate lobe enucleation, on both the HoLEP simulator and with a human cadaveric prostate. We have developed a concentric tube robotic platform that is passed through a standard endoscope that is capable of producing complex movements of the end effectors. We have shown that these movements of the concentric tube manipulators are capable of performing tasks that may eventually translate into improved ease of performing HoLEP.

  3. Toward Improving Transurethral Prostate Surgery: Development and Initial Experiments with a Prototype Concentric Tube Robotic Platform

    Science.gov (United States)

    Hendrick, Richard J.; Webster, Robert J.; Herrell, S. Duke

    2016-01-01

    Abstract Introduction: Despite the potential clinical advantages of holmium laser enucleation of the prostate (HoLEP), there has been reluctance of the urologic community to adopt the procedure, as a result of a perceived steep learning curve. Thus, we sought to design and develop a transurethral endoscopic robotic platform for HoLEP. Materials and Methods: We developed a novel transurethral, concentric tube robotic platform for HoLEP. We conducted magnetic tracking experiments to compare movements of the end effectors of the robot with those of a rigid endoscope. Additionally, we tested the robot on an HoLEP simulator and with a human cadaveric prostate to assess its ability to maneuver within a small working space. Results: In the prostate scanning experiment, the area reached by the robot represents a 65% improvement vs the area accessible by a rigid endoscope without tissue deformation. Additionally, the robot performed well within the confines of the prostatic urethra and was able to successfully complete prostate lobe enucleation, on both the HoLEP simulator and with a human cadaveric prostate. Conclusions: We have developed a concentric tube robotic platform that is passed through a standard endoscope that is capable of producing complex movements of the end effectors. We have shown that these movements of the concentric tube manipulators are capable of performing tasks that may eventually translate into improved ease of performing HoLEP. PMID:26983892

  4. Perceived Importance of Marijuana to the College Experience Scale (PIMCES): Initial Development and Validation.

    Science.gov (United States)

    Pearson, Matthew R; Kholodkov, Tatyana; Gray, Matt J

    2017-03-01

    Internalization of college substance use culture refers to the degree to which an individual perceives the use of that substance to be an integral part of the college experience. Although there is a growing literature characterizing this construct for alcohol, the present study describes the development and validation of a new measure to assess the internalization of the college marijuana use culture, the Perceived Importance of Marijuana to the College Experience Scale (PIMCES). We recruited a large, diverse sample (N = 8,141) of college students from 11 participating universities. We examined the psychometric properties of the PIMCES and evaluated its concurrent validity by examining its associations with marijuana-related outcomes. A single-factor, eight-item PIMCES demonstrated good model fit and high internal consistency (Cronbach's α = .89) and was correlated with marijuana user status, frequency of marijuana use, marijuana consequences, and injunctive norms. Overall, the PIMCES exhibits sound psychometric properties. The PIMCES can serve as a possible mediator of the effects of personality and other factors on marijuana-related outcomes and may be a promising target for marijuana interventions.

  5. Initial posting-a critical stage in the employment cycle: lessons from the experience of government doctors in Gujarat, India.

    Science.gov (United States)

    Purohit, Bhaskar; Martineau, Tim

    2016-07-11

    With the critical shortage of government doctors serving in rural health centers in India, understanding the initial posting policies, processes, and practices become important from a retention point of view. The initial posting is a very critical stage of an employment cycle and could play an important role in influencing the key human resource for health outcomes such as turnover and performance. The current study aimed at exploring a rather unknown phenomenon of the initial posting-related processes, practices, and perceptions of Medical Officers working with the Public Health Department in Gujarat, India. This was an exploratory study carried out in the state of Gujarat, India, that used qualitative methods first to document the extant initial posting policy with the help of document review and five Key Informant interviews; next, 19 in-depth interviews were carried out with Medical Officers to assess implementation of policies as well as processes and systems related to the initial posting of Medical Officers. A thematic framework approach was used to analyze qualitative data using NVIVO. The results indicate that there is no formal published or written initial posting policy in the state, and in the absence of a written and formal policy, the overall posting systems were perceived to be arbitrary by the study respondents. In the absence of any policy, the state has some unwritten informal practices such as posting the Medical Officers at their native places. Although this practice reflects a concern towards the Medical Officer's needs, such practices are not consistently applied indicating some inequity and possible implications over Medical Officers' retention and motivation. Initial posting is a critical aspect of an employment cycle, and the perceptions and experiences of MOs regarding the processes and practices involved in their initial posting can be crucial in influencing their performance and turnover rates. If long-term solutions are to be sought in

  6. Initial experience with Crotalidae polyvalent immune Fab (ovine) antivenom in the treatment of copperhead snakebite.

    Science.gov (United States)

    Lavonas, Eric J; Gerardo, Charles J; O'Malley, Gerald; Arnold, Thomas C; Bush, Sean P; Banner, William; Steffens, Mark; Kerns, William P

    2004-02-01

    Crotalidae polyvalent immune Fab (ovine) (CroFab; FabAV) effectively treats patients bitten by rattlesnakes. The copperhead snake (Agkistrodon contortrix) caused 37% of venomous snakebites reported to US poison centers in 2001 and is the major envenomating reptile in the southeastern United States. FabAV has not been tested in human beings envenomated by copperhead snakes. In this preliminary study, we performed a retrospective chart review of all copperhead snake envenomations reported to the Carolinas Poison Center that were treated with FabAV. Progression of limb swelling, coagulopathy, and hemodynamic status before and after FabAV administration, adverse effects of FabAV therapy, and recurrence phenomena were recorded. Of approximately 400 copperhead envenomation cases reported to the poison center during the study period, 32 received FabAV and were included. Most patients had moderate envenomation. The median time to FabAV administration was 4.0 hours. The median time to achieve initial control was 1.0 hour, with a median dose of 4 vials of FabAV. A rapid initial response, defined as cessation of the progression of local tissue injury within 4 hours of FabAV administration, occurred in 28 cases (88%; 95% confidence interval [CI] 76% to 99%). Four cases (13%; 95% CI 1% to 24%) were considered treatment failures. Recurrent swelling occurred in 6 cases (19%; 95% CI 5% to 32%). The incidence of recurrent swelling was not reduced by administration of repeated doses of antivenom on a planned schedule. One patient developed late-onset coagulopathy. One minor allergic reaction was observed. In this select group of patients bitten by copperhead snakes, local tissue effects of envenomation halted promptly after FabAV treatment in most cases. Treatment failures occurred, and recurrence of swelling and defibrination syndrome was sometimes problematic. Time to return to work and long-term limb function were not assessed. A controlled trial with long-term follow-up is

  7. Initial experience using a bipolar radiofrequency ablation device for hemostasis during thyroidectomy.

    Science.gov (United States)

    Baldwin, Keith; Haniff, Michelle; Somasundar, Ponnandai

    2013-01-01

    The purpose of this study was to evaluate a novel bipolar radiofrequency ablation (BRFA) device using nanotechnology for division of all named vessels during thyroidectomy. All thyroidectomies from January 2008 to July 2010 at a single institution used the BRFA device (EnSeal, Ethicon Endo-Surgery, Cincinnati, OH) for hemostasis. Clinicopathologic data and complications were recorded and compared with existing literature using other energy devices. Fifty-eight thyroidectomies were performed. Mean age was 54.7 years, and mean operating room time was 81 minutes. The average estimated blood loss was 46 mL. Ninety percent of patients were discharged in <23 hours. There were no hemorrhages. There was 1 recurrent laryngeal nerve (RLN) injury, and 1 case of transient hypocalcemia. This first small series using the BRFA device reveals initial safety and effectiveness for thyroid hemostasis, and warrants further study. The minimal thermal spread inherent in this device may make it an attractive option when structures such as the RLN may be near the zone of hemostasis. Copyright © 2011 Wiley Periodicals, Inc.

  8. Can we reduce the burden of depression? The Australian experience with beyondblue: the national depression initiative.

    Science.gov (United States)

    Hickie, Ian

    2004-01-01

    Throughout the Asia Pacific region, there is an urgent need to reduce the burden of depression by increasing depression awareness, reducing stigma and dismantling those social barriers that prevent full participation by people with depression. This paper describes the development and early achievements of the Australian depression initiative, beyondblue. A review of the key priorities of beyondblue and their impacts during the first three years of operation (2001-03). Key achievements include: the degree of national recognition of beyondblue; size and scope of media impact; growth in website utilisation; increased reporting of the community's recognition of people with depression; genuine reforms in life insurance and income protection; development of a new national consumer and carer organisation; establishment of major population-based preventative and early intervention programs; system-wide reform of primary care-based mental health services; national educational program uptake by general practitioners; and, development of key awareness and intervention programs for use in schools and the workplace. In its first three years of operation, beyondblue has had a major impact on depression awareness in Australia and demonstrable gains have been made in reducing stigma and major social barriers. A pre-existing national mental health policy and implementation plan, a substantial funding base and participation by key political, media and community leaders have been essential elements of its short-term success. Its longer-term impact will now depend on more sustainable community and business partnerships as well as the growth of a more influential consumer and carer voice.

  9. Initial experiences of interprofessional problem-based learning: a comparison of male and female students' views.

    Science.gov (United States)

    Reynolds, Frances

    2003-02-01

    Few studies have considered the contribution of problem-based learning (PBL) to interprofessional education, and even fewer have examined whether women and men evaluate PBL differently. This paper examines first year occupational therapy and physiotherapy students' evaluations of their initial participation in PBL, during an interprofessional module focusing on communication skills and patient-focused approaches to care. Questionnaire data included attitude ratings and qualitative evaluations of PBL. A total of 133 females and 24 males responded (comprising 83% of the total cohort). Most students were positive that PBL contributed to both personal learning and team-working skills. Both female and male students felt able to express their opinions within the seminar groups and were positive that their understanding of therapists' roles within the multidisciplinary team had increased. However, women expressed rather more trust in the information provided by other students, confirmed greater enjoyment in taking responsibility for their own learning and had more positive views about working with students from another course. In their qualitative comments, more women made reference to enjoying the social aspects of PBL (such as group work, support and collaboration). The gender differences were not substantial but those that were observed support previous researchers' arguments that women are more inclined to be 'connected learners' who value the social aspects of learning contexts. The findings overall suggested that PBL made a positive, well-received contribution to learning during an interprofessional module.

  10. Significance of assessment experiences during initial teacher training in physical education

    Directory of Open Access Journals (Sweden)

    Wagner dos Santos

    2016-03-01

    Full Text Available Abstract This study investigates how students in the final semester of their teacher training program (licensure at the Center of Physical Education and Sports (CEFD, Espírito Santo Federal University, Brazil, (reinterpret their assessment experiences, an integral component of their teacher training. It employs the narrative as a theoretical and methodological perspective, and it utilizes student portfolios, as well as focus groups and semi-structured individual interviews as inputs for data generation. Ten students in their eighth, or final, semester participated in this study. These were the total respondents to a "call for volunteers" among the 2014 graduating class. The results suggest that the students believe the assessment processes of their teaching practices in physical education are disjointed. They feel that the disciplines that allow them to review their own performance during teacher training are more efficient and play a stronger role in their education.

  11. Laparoscopic pectopexy: initial experience of single center with a new technique for apical prolapse surgery

    Directory of Open Access Journals (Sweden)

    Ahmet Kale

    Full Text Available ABSTRACT Objective: To share our first experience with laparoscopic pectopexy, a new technique for apical prolapse surgery, and to evaluate the feasibility of this technique. Materials and Methods: Seven patients with apical prolapse underwent surgery with laparoscopic pectopexy. The lateral parts of the iliopectineal ligament were used for a bilateral mesh fixation of the descended structures. The medical records of the patients were reviewed, and the short-term clinical outcomes were analyzed. Results: The laparoscopic pectopexy procedures were successfully performed, without intraoperative and postoperative complications. De novo apical prolapse, de novo urgency, de novo constipation, stress urinary incontinence, anterior and lateral defect cystoceles, and rectoceles did not occur in any of the patients during a 6-month follow-up period. Conclusion: Although laparoscopic sacrocolpopexy has shown excellent anatomical and functional long-term results, laparoscopic pectopexy offers a feasible, safe, and comfortable alternative for apical prolapse surgery. Pectopexy may increase a surgeon's technical perspective for apical prolapse surgery.

  12. Pleurectomy/decortication and hyperthermic intrapleural chemotherapy for malignant pleural mesothelioma: initial experience.

    Science.gov (United States)

    Migliore, Marcello; Calvo, Damiano; Criscione, Alessandra; Palmucci, Stefano; Fuccio Sanzà, Giovanni; Caltabiano, Rosario; Spatola, Corrado; Privitera, Giuseppe; Aiello, Marco Maria; Parra, Hector Soto; Ciancio, Nicola; Di Maria, Giuseppe

    2015-01-01

    Cytoreductive surgery and hyperthermic intraoperative intrapleural chemotherapy (HITHOC) are a known option for malignant pleural mesothelioma (MPM). This prospective study was started to prove that pleurectomy/decortication and HITHOC could be successfully performed in a low volume center. Criteria of inclusion were a proven diagnosis of MPM, early-stage disease and good performance status. Six consecutive patients were enrolled. After pleurectomy/decortication, intrapleural cisplatin was administered for 60 min at 42.5 °C. Wedge resections and diaphragmatic reconstruction were added in two and one patient, respectively. Morbidity was 16.6%. Mortality was nil. Hospital stay was 7.8 days. Mean survival was 21.5 months (range: 6-30). This small experience confirms that pleurectomy/decortication and HITHOC are a good therapeutic option in the multimodality treatment of MPM. A randomized controlled trial is necessary.

  13. Experimental warming delays autumn senescence in a boreal spruce bog: Initial results from the SPRUCE experiment

    Science.gov (United States)

    Richardson, Andrew; Furze, Morgan; Aubrecht, Donald; Milliman, Thomas; Nettles, Robert; Krassovski, Misha; Hanson, Paul

    2016-04-01

    Phenology is considered one of the most robust indicators of the biological impacts of global change. In temperate and boreal regions, long-term data show that rising temperatures are advancing spring onset (e.g. budburst and flowering) and delaying autumn senescence (e.g. leaf coloration and leaf fall) in a wide range of ecosystems. While warm and cold temperatures, day length and insolation, precipitation and water availability, and other factors, have all been shown to influence plant phenology, the future response of phenology to rising temperatures and elevated CO2 still remains highly uncertain because of the challenges associated with conducting realistic manipulative experiments to simulate future environmental conditions. At the SPRUCE (Spruce and Peatland Responses Under Climatic and Environmental Change) experiment in the north-central United States, experimental temperature (0 to +9° C above ambient) and CO2 (ambient and elevated) treatments are being applied to mature, and intact, Picea mariana-Sphagnum spp. bog communities in their native habitat through the use of ten large (approximately 12 m wide, 10 m high) open-topped enclosures. We are tracking vegetation green-up and senescence in these chambers, at both the individual and whole-community level, using repeat digital photography. Within each chamber, digital camera images are recorded every 30 minutes and uploaded to the PhenoCam (http://phenocam.sr.unh.edu) project web page, where they are displayed in near-real-time. Image processing is conducted nightly to extract quantitative measures of canopy color, which we characterize using Gcc, the green chromatic coordinate. Data from a camera mounted outside the chambers (since November 2014) indicate strong seasonal variation in Gcc for both evergreen shrubs and trees. Shrub Gcc rises steeply in May and June, and declines steeply in September and October. By comparison, tree Gcc rises gradually from March through June, and declines gradually from

  14. [Curriculum for additional advanced specialist training in psychotherapy--concept and initial experience in practice].

    Science.gov (United States)

    Fritzsche, Kurt

    2008-01-01

    The regulations for advanced specialist training passed by the German Medical Council in May 2003 make it possible for any clinical physician to complete advanced training for "specialty-related psychotherapy". Critics see this as a "watering down" of medical psychotherapy. The majority applaud the greater proximity to practice and the possibility of achieving psychosomatic expertise. The new advanced specialist training regulations permit therapeutic interventions by the primary care physician beyond psychosomatic primary care. A curriculum has been developed in the Department of Psychosomatic Medicine and Psychotherapy of the University Hospital Freiburg, which has completed the pilot phase and is now offered in block courses over a period of 2 years. We present here experience with the new concept and the results of the evaluation.

  15. Crossing the gender boundaries: The gender experiences of male nursing students in initial nursing clinical practice in Taiwan.

    Science.gov (United States)

    Liu, Hsing-Yuan; Li, Yun Ling

    2017-11-01

    The initial nursing clinical practice is the necessary practicum required for nursing students. Because of the changing learning style, many of them are under great pressure for environmental change and therefore their daily routine is severe affected. Interacting directly with patients in a female-dominated occupation, along with the general gender stereotypes, the impact is especially significant to male nursing students than to female nursing students. The purpose of this preliminary qualitative study is to explore the gendered experiences of male nursing students during their first initial nursing clinical practice. Both focus group interviews and individual interviews are conducted with twenty-two sophomore nursing students from a university of technology in northern Taiwan, with ten male students and twelve female students. Two main themes emerge from the gendered experiences shared by the nursing students: Gender consciousness awakening and thus maintaining masculinity, and male advantage in the learning environments. The results identify the specific gendered experiences of nursing students, providing implications for future nursing education and counseling service. Further, this study may serve to promote an active yet gender-sensitive nursing education for training nursing professionals. Published by Elsevier Ltd.

  16. The role of model and initial condition error in numerical weather forecasting investigated with an observing system simulation experiment

    Directory of Open Access Journals (Sweden)

    Nikki C. Privé

    2013-11-01

    Full Text Available A series of experiments that explore the roles of model and initial condition error in numerical weather prediction are performed using an observing system simulation experiment (OSSE framework developed at the National Aeronautics and Space Administration Global Modeling and Assimilation Office (NASA/GMAO. The use of an OSSE allows the analysis and forecast errors to be explicitly calculated, and different hypothetical observing networks can be tested with ease. In these experiments, both a full global OSSE framework and an ‘identical twin’ OSSE setup are used to compare the behaviour of the data assimilation system (DAS and evolution of forecast skill with and without model error. The initial condition error is manipulated by varying the distribution and quality of the observing network and the magnitude of observation errors. The results show that model error has a strong impact on both the quality of the analysis field and the evolution of forecast skill, including both systematic and unsystematic model error components. With a realistic observing network, the analysis state retains a significant quantity of error due to systematic model error. If errors of the analysis state are minimised, model error acts to rapidly degrade forecast skill during the first 24–48 hours of forward integration. In the presence of model error, the impact of observation errors on forecast skill is small, but in the absence of model error, observation errors cause a substantial degradation of the skill of medium-range forecasts.

  17. Initiation of a medical genetics service in sub-Saharan Africa: experience of prenatal diagnosis in Cameroon.

    Science.gov (United States)

    Wonkam, Ambroise; Tekendo, Cedrik Ngongang; Sama, Dohbit Julius; Zambo, Huguette; Dahoun, Sophie; Béna, Frédérique; Morris, Michael A

    2011-01-01

    Initiation of Prenatal Genetic Diagnosis (PND) has laid the foundation of the first medical genetic service in Cameroon. Cross-sectional descriptive study, illustrating some aspects of the genetic service using a small 24-months PND experience. The service began with a medical geneticist who had to follow-up the building and equipments supplies of the diagnosis laboratory; and to personally perform genetic consultations, molecular experiments and post-results counseling. PND was indicated for sickle cell disease (SCD) in 33 cases (55%) and chromosomal anomalies in 27 cases (45%). With international collaboration, DNA analysis revealed 6 SCD-affected foetuses (20.7%); QF-PCR (N=25) and full karyotype (N=8) analysis revealed cases of trisomy 21 and trisomy 18. Following PND success, national effort granted more human and material resources to improve the service. The preliminary experience was made possible by three factors: 1) the availability of a trained Cameroonian medical geneticist 2) the availability of obstetricians trained in fetal medicine and 3) advocacy initiatives at national and international levels, which have proven invaluable for advice, training, sourcing of materials, and back-up reference diagnostic laboratory. The practice of medical genetics, involving prenatal genetic diagnosis of sickle cell disease and chromosomal anomalies, is possible in Cameroon (sub-Saharan Africa). Copyright © 2011 Elsevier Masson SAS. All rights reserved.

  18. Initial experience at a university teaching hospital from using telemedicine to promote education through video conferencing

    Directory of Open Access Journals (Sweden)

    Bruno Monteiro Tavares Pereira

    Full Text Available CONTEXT AND OBJECTIVE: Telehealth and telemedicine services are advancing rapidly, with an increasing spectrum of information and communication technologies that can be applied broadly to the population's health, and to medical education. The aim here was to report our institution's experience from 100 videoconferencing meetings between five different countries in the Americas over a one-year period. DESIGN AND SETTING: Retrospective study at Universidade Estadual de Campinas. METHODS: Through a Microsoft Excel database, all conferences in all specialties held at our institution from September 2009 to August 2010 were analyzed retrospectively. RESULTS: A total of 647 students, physicians and professors participated in telemedicine meetings. A monthly mean of 8.3 (± 4.3 teleconferences were held over the analysis period. Excluding holidays and the month of inaugurating the telemedicine theatre, our teleconference rate reached a mean of 10.3 (± 2.7, or two teleconferences a week, on average. Trauma surgery and meetings on patient safety were by far the most common subjects discussed in our teleconference meetings, accounting for 22% and 21% of the total calls. CONCLUSION: Our experience with telemedicine meetings has increased students' interest; helped our institution to follow and discuss protocols that are already accepted worldwide; and stimulated professors to promote telemedicine-related research in their own specialties and keep up-to-date. These high-technology meetings have shortened distances in our vast country, and to other reference centers abroad. This virtual proximity has enabled discussion of international training with students and residents, to increase their overall knowledge and improve their education within this institution.

  19. Private initiatives and policy options: recent health system experience in India.

    Science.gov (United States)

    Purohit, B C

    2001-03-01

    In the recent past the impact of structural adjustment in the Indian health care sector has been felt in the reduction in central grants to States for public health and disease control programmes. This falling share of central grants has had a more pronounced impact on the poorer states, which have found it more difficult to raise local resources to compensate for this loss of revenue. With the continued pace of reforms, the likelihood of increasing State expenditure on the health care sector is limited in the future. As a result, a number of notable trends are appearing in the Indian health care sector. These include an increasing investment by non-resident Indians (NRIs) in the hospital industry, leading to a spurt in corporatization in the States of their original domicile and an increasing participation by multinational companies in diagnostics aiming to capture the potential of the Indian health insurance market. The policy responses to these private initiatives are reflected in measures comprising strategies to attract private sector participation and management inputs into primary health care centres (PHCs), privatization or semi-privatization of public health facilities such as non-clinical services in public hospitals, innovating ways to finance public health facilities through non-budgetary measures, and tax incentives by the State governments to encourage private sector investment in the health sector. Bearing in mind the vital importance of such market forces and policy responses in shaping the future health care scenario in India, this paper examines in detail both of these aspects and their implications for the Indian health care sector. The analysis indicates that despite the promising newly emerging atmosphere, there are limits to market forces; appropriate refinement in the role of government should be attempted to avoid undesirable consequences of rising costs, increasing inequity and consumer exploitation. This may require opening the health

  20. Initial Surgical Experience with Aortic Valve Repair: Clinical and Echocardiographic Results

    Science.gov (United States)

    da Costa, Francisco Diniz Affonso; Colatusso, Daniele de Fátima Fornazari; da Costa, Ana Claudia Brenner Affonso; Balbi Filho, Eduardo Mendel; Cavicchioli, Vinicius Nesi; Lopes, Sergio Augusto Veiga; Ferreira, Andrea Dumsch de Aragon; Collatusso, Claudinei

    2016-01-01

    Introduction Due to late complications associated with the use of conventional prosthetic heart valves, several centers have advocated aortic valve repair and/or valve sparing aortic root replacement for patients with aortic valve insufficiency, in order to enhance late survival and minimize adverse postoperative events. Methods From March/2012 thru March 2015, 37 patients consecutively underwent conservative operations of the aortic valve and/or aortic root. Mean age was 48±16 years and 81% were males. The aortic valve was bicuspid in 54% and tricuspid in the remaining. All were operated with the aid of intraoperative transesophageal echocardiography. Surgical techniques consisted of replacing the aortic root with a Dacron graft whenever it was dilated or aneurysmatic, using either the remodeling or the reimplantation technique, besides correcting leaflet prolapse when present. Patients were sequentially evaluated with clinical and echocardiographic studies and mean follow-up time was 16±5 months. Results Thirty-day mortality was 2.7%. In addition there were two late deaths, with late survival being 85% (CI 95% - 68%-95%) at two years. Two patients were reoperated due to primary structural valve failure. Freedom from reoperation or from primary structural valve failure was 90% (CI 95% - 66%-97%) and 91% (CI 95% - 69%-97%) at 2 years, respectively. During clinical follow-up up to 3 years, there were no cases of thromboembolism, hemorrhage or endocarditis. Conclusions Although this represents an initial series, these data demonstrates that aortic valve repair and/or valve sparing aortic root surgery can be performed with satisfactory immediate and short-term results. PMID:27556321

  1. Reflectance confocal microscopy-guided laser ablation of basal cell carcinomas: initial clinical experience

    Science.gov (United States)

    Sierra, Heidy; Yélamos, Oriol; Cordova, Miguel; Chen, Chih-Shan Jason; Rajadhyaksha, Milind

    2017-08-01

    Laser ablation offers a procedure for precise, fast, and minimally invasive removal of superficial and early nodular basal cell carcinomas (BCCs). However, the lack of histopathological confirmation has been a limitation toward widespread use in the clinic. A reflectance confocal microscopy (RCM) imaging-guided approach offers cellular-level histopathology-like feedback directly on the patient, which may then guide and help improve the efficacy of the ablation procedure. Following an ex vivo benchtop study (reported in our earlier papers), we performed an initial study on 44 BCCs on 21 patients in vivo, using a pulsed erbium:ytterbium aluminum garnet laser and a contrast agent (aluminum chloride). In 10 lesions on six patients, the RCM imaging-guided detection of either presence of residual tumor or complete clearance was immediately confirmed with histopathology. Additionally, 34 BCCs on 15 patients were treated with RCM imaging-guided laser ablation, with immediate confirmation for clearance of tumor (no histopathology), followed by longer-term monitoring, currently in progress, with follow-up imaging (again, no histopathology) at 3, 6, and 18 months. Thus far, the imaging resolution appears to be sufficient and consistent for monitoring efficacy of ablation in the wound, both immediately postablation and subsequently during recovery. The efficacy results appear to be promising, with observed clearance in 19 cases of 22 cases with follow-ups ranging from 6 to 21 months. An additional 12 cases with 1 to 3 months of follow-ups has shown clearance of tumor but a longer follow-up time is required to establish conclusive results. Further instrumentation development will be necessary to cover larger areas with a more automatically controlled instrument for more uniform, faster, and deeper imaging of margins.

  2. [Unreamed tibial nail in tibial shaft fractures with severe soft tissue damage. Initial clinical experiences].

    Science.gov (United States)

    Krettek, C; Haas, N; Schandelmaier, P; Frigg, R; Tscherne, H

    1991-11-01

    In a prospective study, since March 1989, 55 tibial shaft fractures have been treated with a new, unreamed solid tibial nail (UTN). This nail was initially designed as a temporary implant. The first 33 cases with second or third degree soft tissue damage were reviewed 6 months or more after the operation. Fractures were classified according to Müller: 6 type A (18.2%), 15 type B (45.5%), and 12 type C (36.7%). In 9 cases (27.3%), there was GII (n = 4) or GIII (n = 5) closed soft tissue damage according to Tscherne's classification. The 24 open fractures (72.7%) comprised 11 OII, 3 OIIIA and 10 OIIIB fractures (Gustilo classification). 24 patients (72.7%) were polytraumatized, the mean PTS (Hannover Polytrauma Score) was 18 points (range: 8-65 points). All fractures were stabilized without reaming. The implant diameter was 8mm (n = 14) or 9 mm (n = 19). Static locking was performed in 31 cases. Dermatofasciotomy was necessary because of compartment syndrome in 14 cases. In 1 grade IIIB open fracture soft tissue coverage was performed with a latissimus dorsi myocutaneous free flap 4 days after nailing. In 32 of the 33 cases the use of an additional cast or brace was not necessary during the follow-up treatment; 1 patient had a cast for 8 weeks for the treatment of accompanying injuries. Full weight-bearing was achieved in 5 cases within 3 weeks, in 16 cases within 12 weeks, and in 30 cases within 26 weeks. In 16 cases (48.5%) the interlocking screws were removed after 5-26 weeks (mean: 10 weeks).(ABSTRACT TRUNCATED AT 250 WORDS)

  3. Establishing a health demographic surveillance site in Bhaktapur district, Nepal: initial experiences and findings

    Science.gov (United States)

    2012-01-01

    Background A health demographic surveillance system (HDSS) provides longitudinal data regarding health and demography in countries with coverage error and poor quality data on vital registration systems due to lack of public awareness, inadequate legal basis and limited use of data in health planning. The health system in Nepal, a low-income country, does not focus primarily on health registration, and does not conduct regular health data collection. This study aimed to initiate and establish the first HDSS in Nepal. Results We conducted a baseline survey in Jhaukhel and Duwakot, two villages in Bhaktapur district. The study surveyed 2,712 households comprising a total population of 13,669. The sex ratio in the study area was 101 males per 100 females and the average household size was 5. The crude birth and death rates were 9.7 and 3.9/1,000 population/year, respectively. About 11% of births occurred at home, and we found no mortality in infants and children less than 5 years of age. Various health problems were found commonly and some of them include respiratory problems (41.9%); headache, vertigo and dizziness (16.7%); bone and joint pain (14.4%); gastrointestinal problems (13.9%); heart disease, including hypertension (8.8%); accidents and injuries (2.9%); and diabetes mellitus (2.6%). The prevalence of non-communicable disease (NCD) was 4.3% (95% CI: 3.83; 4.86) among individuals older than 30 years. Age-adjusted odds ratios showed that risk factors, such as sex, ethnic group, occupation and education, associated with NCD. Conclusion Our baseline survey demonstrated that it is possible to collect accurate and reliable data in a village setting in Nepal, and this study successfully established an HDSS site. We determined that both maternal and child health are better in the surveillance site compared to the entire country. Risk factors associated with NCDs dominated morbidity and mortality patterns. PMID:22950751

  4. Evolution of male rectal prolapse surgery and initial experience of robotic rectopexy in men.

    Science.gov (United States)

    Siddika, Arifa; Saha, Sunita; Siddiqi, Shahab

    2017-09-01

    Laparoscopic ventral mesh rectopexy (LVMR) has proven benefit in the treatment of external rectal prolapse and symptomatic internal rectal prolapse in women. However, there is a recurrence rate of 4-50% depending on indication. Some of this recurrence is attributable to persistent lateral and posterior prolapses. Modifications of LVMR (modified Orr-Loygue rectopexies) describe an additional narrow posterior rectal mesh fixed to the mesorectal fat, which is inherently insecure. Additional complications in men include sexual dysfunction caused by nerve damage from the ventral rectal dissection. There is one case series in men, published by a surgeon with an unusually large practice, showing LVMR to have a good success rate with low rates of sexual dysfunction. Other series have contained small numbers of men, but subgroup analysis to determine success and complication rates is not possible. Robotic surgery is more precise than laparoscopic surgery, allows stereotactic vision, and has a stable platform. We have developed a robotic modified Orr-Loygue rectopexy in an attempt to deal with the persistent components of posterior rectal prolapse by placing a mesh posteriorly through a narrow dissection and securing the mesh to the distal rectal muscle tube. Mesh-to-muscle fixation is more secure than mesh-to-mesorectal fat fixation. The robotic platform also improves the accuracy of ventral dissection and reduces the risk of sexual dysfunction in men. Our initial results indicate that robotic modified Orr-Loygue rectopexy is a safe and feasible option for rectal prolapse in men, with no more complications or recurrences than the best published outcomes for LVMR.

  5. Conceptual design of initial opacity experiments on the national ignition facility

    Energy Technology Data Exchange (ETDEWEB)

    Heeter, R.  F.; Bailey, J.  E.; Craxton, R.  S.; DeVolder, B.  G.; Dodd, E.  S.; Garcia, E.  M.; Huffman, E.  J.; Iglesias, C.  A.; King, J.  A.; Kline, J.  L.; Liedahl, D.  A.; McKenty, P.  W.; Opachich, Y.  P.; Rochau, G.  A.; Ross, P.  W.; Schneider, M.  B.; Sherrill, M.  E.; Wilson, B.  G.; Zhang, R.; Perry, T.  S.

    2017-01-09

    Accurate models of X-ray absorption and re-emission in partly stripped ions are necessary to calculate the structure of stars, the performance of hohlraums for inertial confinement fusion and many other systems in high-energy-density plasma physics. Despite theoretical progress, a persistent discrepancy exists with recent experiments at the Sandia Z facility studying iron in conditions characteristic of the solar radiative–convective transition region. The increased iron opacity measured at Z could help resolve a longstanding issue with the standard solar model, but requires a radical departure for opacity theory. To replicate the Z measurements, an opacity experiment has been designed for the National Facility (NIF). The design uses established techniques scaled to NIF. A laser-heated hohlraum will produce X-ray-heated uniform iron plasmas in local thermodynamic equilibrium (LTE) at temperatures${\\geqslant}150$ eV and electron densities${\\geqslant}7\\times 10^{21}~\\text{cm}^{-3}$. The iron will be probed using continuum X-rays emitted in a${\\sim}200$ ps,${\\sim}200~\\unicode[STIX]{x03BC}\\text{m}$diameter source from a 2 mm diameter polystyrene (CH) capsule implosion. In this design

  6. Emerging Pathogens Initiative (EPI)

    Data.gov (United States)

    Department of Veterans Affairs — The Emerging Pathogens Initiative (EPI) database contains emerging pathogens information from the local Veterans Affairs Medical Centers (VAMCs). The EPI software...

  7. [Regadenoson as a new stress agent in myocardial perfusion imaging. Initial experience in The Netherlands].

    Science.gov (United States)

    Jager, P L; Buiting, M; Mouden, M; Oostdijk, A H J; Timmer, J; Knollema, S

    2014-01-01

    Regadenoson is a recently approved selective adenosine-2A receptor agonist to induce pharmacological stress in myocardial perfusion imaging (MPI) procedures using a single bolus injection. We included 123 patients referred for MPI because of suspected coronary arterial disease (CAD). Of these, 66 patients underwent a regadenoson stress test and 57 patients underwent an adenosine stress test preceding standard myocardial SPECT imaging. Technicians, physicians and patients were asked to report their experience using questionnaires. As compared to adenosine, regadenoson did not produce any atrio-ventricular block (0 vs. 10% with adenosine), but did produce minor tachycardia and minimal blood pressure changes while all other side effects were milder and shorter. There were fewer patients with severe complaints after taking regadenoson than adenosine (17% vs. 32%, respectively, p<0.01). The most frequent complaint reported was dyspnea, followed by flushing and chest pain. However, when they did occur, they usually disappeared rapidly. The overall symptom score, including severity and duration of side effects, was significantly lower after regadenoson than after adenosine (6.7±6.3 vs. 10.0±7.9, respectively; p<0.01.) SPECT imaging results were similar. The regadenoson procedure was faster and more practical. Regadenoson, the new selective adenosine-2A receptor agonist, is a stress agent for MPI with a patient- and department friendly profile. Copyright © 2014 Elsevier España, S.L.U. and SEMNIM. All rights reserved.

  8. Initial SAM Calibration Gas Experiments on Mars: Quadrupole Mass Spectrometer Results and Implications

    Science.gov (United States)

    Franz, Heather B.; Trainer, Melissa G.; Malespin, Charles A.; Mahaffy, Paul R.; Atreya, Sushil K.; Becker, Richard H,; Benna, Mehdi; Conrad, Pamela G.; Eigenbrode, Jennifer L.; Freissinet, Caroline; hide

    2017-01-01

    The Sample Analysis at Mars (SAM) instrument suite of the Mars Science Laboratory (MSL) Curiosity rover is equipped to analyze both martian atmospheric gases and volatiles released by pyrolysis of solid surface materials, with target measurements including chemical and isotopic composition (Mahaffy et al., 2012). To facilitate assessment of instrument performance and validation of results obtained on Mars, SAM houses a calibration cell containing CO2, Ar, N2, Xe, and several fluorinated hydrocarbon compounds (Franz et al., 2014; Mahaffy et al., 2012). This report describes the first two experiments utilizing this calibration cell on Mars and gives results from analysis of data acquired with the SAM Quadrupole Mass Spectrometer (QMS). These data support the accuracy of isotope ratios obtained with the QMS (Conrad et al., 2016; Mahaffy et al., 2013) and provide ground-truth for reassessment of analytical constants required for atmospheric measurements, which were reported in previous contributions (Franz et al., 2015, 2014). The most significant implication of the QMS data involves reinterpretation of pre-launch contamination previously believed to affect only CO abundance measurements (Franz et al., 2015) to affect N2 abundances, as well. The corresponding adjustment to the N2 calibration constant presented here brings the atmospheric volume mixing ratios for Ar and N2 retrieved by SAM into closer agreement with those reported by the Viking mission (Owen et al., 1977; Oyama and Berdahl, 1977).

  9. Initial experience with a group presentation of study results to research participants

    Directory of Open Access Journals (Sweden)

    Bent Stephen

    2008-03-01

    Full Text Available Abstract Background Despite ethical imperatives, informing research participants about the results of the studies in which they take part is not often performed. This is due, in part, to the costs and burdens of communicating with each participant after publication of the results. Methods Following the closeout and publication of a randomized clinical trial of saw palmetto for treatment of symptoms of benign prostatic hyperplasia, patients were invited back to the research center to participate in a group presentation of the study results. Results Approximately 10% of participants attended one of two presentation sessions. Reaction to the experience of the group presentation was very positive among the attendees. Conclusion A group presentation to research participants is an efficient method of communicating study results to those who desire to be informed and was highly valued by those who attended. Prospectively planning for such presentations and greater scheduling flexibility may result in higher attendance rates. Trial Registration Number Clinicaltrials.gov #NCT00037154

  10. Visualization of the meridian of traditional Chinese medicine with electrical impedance tomography: An initial experience

    Science.gov (United States)

    Cao, Yanli; Lu, Xiaozuo; Wang, Xuemin

    2010-04-01

    The meridian is a concept central to traditional Chinese medical techniques such as acupuncture. There is no physically verifiable anatomical or histological basis for the existence of meridians. In Chinese medicine, the meridians are channels along which the energy of the psychological system is considered to flow. It has been proven that the resistance along the meridian channels is lower compared to other paths. Based on this knowledge, we proposed using electrical impedance tomography (EIT) to visualize the meridians of human being. A simplified three dimensional (3D) mathematical model of the forearm developed. Current was injected in the direction perpendicular to the cross-section where eight electrodes were equally placed around the surface of the forearm for the voltage measurements. The model was solved using Finite Element Method (FEM) and dynamic image was reconstructed using truncated singular value decomposition (TSVD) regularization method. The conductivity distributions were compared with different current injections, along the meridian channel and channels around respectively. We also conducted experiments on models and the meridians were shown in final reconstructed images.

  11. Initial SAM calibration gas experiments on Mars: Quadrupole mass spectrometer results and implications

    Science.gov (United States)

    Franz, Heather B.; Trainer, Melissa G.; Malespin, Charles A.; Mahaffy, Paul R.; Atreya, Sushil K.; Becker, Richard H.; Benna, Mehdi; Conrad, Pamela G.; Eigenbrode, Jennifer L.; Freissinet, Caroline; Manning, Heidi L. K.; Prats, Benito D.; Raaen, Eric; Wong, Michael H.

    2017-04-01

    The Sample Analysis at Mars (SAM) instrument suite of the Mars Science Laboratory (MSL) Curiosity rover is equipped to analyze both martian atmospheric gases and volatiles released by pyrolysis of solid surface materials, with target measurements including chemical and isotopic composition (Mahaffy et al., 2012). To facilitate assessment of instrument performance and validation of results obtained on Mars, SAM houses a calibration cell containing CO2, Ar, N2, Xe, and several fluorinated hydrocarbon compounds (Franz et al., 2014; Mahaffy et al., 2012). This report describes the first two experiments utilizing this calibration cell on Mars and gives results from analysis of data acquired with the SAM Quadrupole Mass Spectrometer (QMS). These data support the accuracy of isotope ratios obtained with the QMS (Conrad et al., 2016; Mahaffy et al., 2013) and provide ground-truth for reassessment of analytical constants required for atmospheric measurements, which were reported in previous contributions (Franz et al., 2015, 2014). The most significant implication of the QMS data involves reinterpretation of pre-launch contamination previously believed to affect only CO abundance measurements (Franz et al., 2015) to affect N2 abundances, as well. The corresponding adjustment to the N2 calibration constant presented here brings the atmospheric volume mixing ratios for Ar and N2 retrieved by SAM into closer agreement with those reported by the Viking mission (Owen et al., 1977; Oyama and Berdahl, 1977).

  12. Use of natural user interfaces for image navigation during laparoscopic surgery: initial experience.

    Science.gov (United States)

    Sánchez-Margallo, Francisco M; Sánchez-Margallo, Juan A; Moyano-Cuevas, José L; Pérez, Eva María; Maestre, Juan

    2017-10-01

    Surgical environments require special aseptic conditions for direct interaction with the preoperative images. We aim to test the feasibility of using a set of gesture control sensors combined with voice control to interact in a sterile manner with preoperative information and an integrated operating room (OR) during laparoscopic surgery. Two hepatectomies and two partial nephrectomies were performed by three experienced surgeons in a porcine model. The Kinect, Leap Motion, and MYO armband in combination with voice control were used as natural user interfaces (NUIs). After surgery, surgeons completed a questionnaire about their experience. Surgeons required <10 min training with each NUI. They stated that NUIs improved the access to preoperative patient information and kept them more focused on the surgical site. The Kinect system was reported as the most physically demanding NUI and the MYO armband in combination with voice commands as the most intuitive and accurate. The need to release one of the laparoscopic instruments in order to use the NUIs was identified as the main limitation. The presented NUIs are feasible to directly interact in a more intuitive and sterile manner with the preoperative images and the integrated OR functionalities during laparoscopic surgery.

  13. Relational representation for improved decisions with an information-theoretic CADe system: initial experience

    Science.gov (United States)

    Mazurowski, Maciej A.; Tourassi, Georgia D.

    2009-02-01

    Our previously presented information-theoretic computer-aided detection (IT-CADe) system for distinguishing masses and normal parenchyma in mammograms is an example of a case-based system. IT-CAD makes decisions by evaluating the querys average similarity with known mass and normal examples stored in the systems case base. Pairwise case similarity is measured in terms of their normalized mutual information. The purpose of this study was to evaluate whether incorporating a new machine learning concept of relational representation to IT-CAD is a more effective strategy than the decision algorithm that is currently in place. A trainable relational representation classifier builds a decision rule using the relational representation of cases. Instead of describing a case by a vector of intrinsic features, the case is described by its NMI-based similarity to a set of known examples. For this study, we first applied random mutation hill climbing algorithm to select the concise set of knowledge cases and then we applied a support vector machine to derive a decision rule using the relational representation of cases. We performed the study with a database of 600 mammographic regions of interest (300 with masses and 300 with normal parenchyma). Our experiments indicate that incorporating the concept of relational representation with a trainable classifier to IT-CAD provides an improvement in performance as compared with the original decision rule. Therefore, relational representation is a promising strategy for IT-CADe.

  14. Torsades de pointes liability inter-model comparisons: the experience of the QT PRODACT initiative.

    Science.gov (United States)

    Hashimoto, Keitaro

    2008-08-01

    Safety pharmacologists from the Japanese pharmaceutical industries and contract laboratories made a database to evaluate drug effects on the QT interval in 2005. This QT PRODACT project was a prospective study of 12 QT-prolonging (positive) drugs and 10 non-prolonging (negative) drugs to evaluate the specificity and sensitivity of several in vivo and in vitro animal models: in vitro guinea pig papillary muscle action potential recordings and in vivo ECG recordings in unanesthetized or anesthetized beagle dogs, cynomolgus monkeys and miniature pigs. In guinea pig papillary muscle action potential recordings, positive drugs showed lengthening of the action potential duration (APD). By using a new measure to detect triangulation of the action potential configuration, an IKr blocking activity of drugs with Ca channel blocking action was detected. All in vivo studies showed a QT-prolonging effect of greater than 10% for the positive drugs. These in vivo models were useful to distinguish positive from negative drugs. The QT PRODACT project showed reliability and sensitivity of the experiments to detect positive drugs. The proarrhythmic effects of these positive drugs could not be detected even though, in some animal models (e.g., unanesthetized monkey), torsades de pointes (TdP)-type arrhythmias were shown by terfenadine. We compared in vivo arrhythmia models for proarrhythmia. The halothane-anesthetized open chest coronary occlusion-reperfusion canine model, the halothane-adrenaline arrhythmia model and the chronic AV block dog models seemed to be useful to detect the arrhythmogenic potential of QT-prolonging drugs.

  15. Initial development of a patient-reported outcome measure of experience with cognitive impairment associated with schizophrenia

    Directory of Open Access Journals (Sweden)

    Welch LC

    2017-06-01

    Full Text Available Lisa C Welch,1 Jeremiah J Trudeau,2 Steven M Silverstein,3 Michael Sand,4 David C Henderson,5 Raymond C Rosen6 1Tufts Clinical and Translational Science Institute, Tufts Medical Center, Boston, MA, 2Health Economics and Outcomes Research, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, 3University Behavioral Health Care, Department of Psychiatry, Rutgers University, Piscataway, NJ, 4Clinical Development and Medical Affairs, Boehringer Ingelheim Pharmaceuticals, Ridgefield, CT, 5Boston Medical Center, School of Medicine, Boston Univeristy, Boston, 6Epidemiology, New England Research Institutes, Watertown, MA, USA Abstract: Cognitive impairment is a serious, often distressing aspect of schizophrenia that affects patients’ day-to-day lives. Although several interview-based instruments exist to assess cognitive functioning, a reliable measure developed based on the experiences of patients facing cognitive difficulties is needed to complement the objective performance-based assessments. The present article describes the initial development of a patient-reported outcome (PRO measure to assess the subjective experience of cognitive impairment among patients with schizophrenia, the Patient-Reported Experience of Cognitive Impairment in Schizophrenia (PRECIS. The phases of development included the construction of a conceptual model based on the existing knowledge and two sets of qualitative interviews with patients: 1 concept elicitation interviews to ensure face and content validity from the perspective of people with schizophrenia and 2 cognitive debriefing of the initial item pool. Input from experts was elicited throughout the process. The initial conceptual model included seven domains. The results from concept elicitation interviews (n=80 supported these domains but yielded substantive changes to concepts within domains and to terminology. Based on these results, an initial pool of 53 items was developed to reflect the most common

  16. PET/MR in children. Initial clinical experience in paediatric oncology using an integrated PET/MR scanner

    OpenAIRE

    Hirsch, Franz Wolfgang; Sattler, Bernhard; Sorge, Ina; Kurch, Lars; Viehweger, Adrian; Ritter, Lutz; WERNER, Peter; Jochimsen, Thies; Barthel, Henryk; Bierbach, Uta; Till, Holger; Sabri, Osama; Kluge, Regine

    2013-01-01

    Use of PET/MR in children has not previously been reported, to the best of our knowledge. Children with systemic malignancies may benefit from the reduced radiation exposure offered by PET/MR. We report our initial experience with PET/MR hybrid imaging and our current established sequence protocol after 21 PET/MR studies in 15 children with multifocal malignant diseases. The effective dose of a PET/MR scan was only about 20% that of the equivalent PET/CT examination. Simultaneous acquisition ...

  17. VORTEX: Versatile and open subsea robot for technical experiment: Prototyping software architecture for the next AUV and ROV generation

    Energy Technology Data Exchange (ETDEWEB)

    Rigaud, V. [IFREMER, Toulon (France); Le Rest, E.; Marce, L. [UBO Limi Lab., Brest (France); Coste Maniere, E.; Simon, D. [INRIA Icare Project, Nice (France); Peuch, A.; Perrier, M. [IFREMER, Toulon (France)

    1994-12-31

    This paper describes a new experimental vehicle named V.O.R.T.E.X. (Versatile and Open subsea Robot for Technical EXperiment) built by the Subsea Robotics Laboratory at the French institute for Sea exploitation (Ifremer). The aim of this project is to work out the metamorphosis of a classical ROV architecture into an AUV architecture in particular for the control and programming architecture design. This vehicle is also designed to emulate the new IFREMER ROV6000 and the future Abyssal Survey Vehicle AUV, from a functional point of view.

  18. Establishing a health demographic surveillance site in Bhaktapur district, Nepal: initial experiences and findings

    Directory of Open Access Journals (Sweden)

    Aryal Umesh

    2012-09-01

    Full Text Available Abstract Background A health demographic surveillance system (HDSS provides longitudinal data regarding health and demography in countries with coverage error and poor quality data on vital registration systems due to lack of public awareness, inadequate legal basis and limited use of data in health planning. The health system in Nepal, a low-income country, does not focus primarily on health registration, and does not conduct regular health data collection. This study aimed to initiate and establish the first HDSS in Nepal. Results We conducted a baseline survey in Jhaukhel and Duwakot, two villages in Bhaktapur district. The study surveyed 2,712 households comprising a total population of 13,669. The sex ratio in the study area was 101 males per 100 females and the average household size was 5. The crude birth and death rates were 9.7 and 3.9/1,000 population/year, respectively. About 11% of births occurred at home, and we found no mortality in infants and children less than 5 years of age. Various health problems were found commonly and some of them include respiratory problems (41.9%; headache, vertigo and dizziness (16.7%; bone and joint pain (14.4%; gastrointestinal problems (13.9%; heart disease, including hypertension (8.8%; accidents and injuries (2.9%; and diabetes mellitus (2.6%. The prevalence of non-communicable disease (NCD was 4.3% (95% CI: 3.83; 4.86 among individuals older than 30 years. Age-adjusted odds ratios showed that risk factors, such as sex, ethnic group, occupation and education, associated with NCD. Conclusion Our baseline survey demonstrated that it is possible to collect accurate and reliable data in a village setting in Nepal, and this study successfully established an HDSS site. We determined that both maternal and child health are better in the surveillance site compared to the entire country. Risk factors associated with NCDs dominated morbidity and mortality patterns.

  19. Safety of autologous bone marrow aspiration concentrate transplantation: initial experiences in 101 patients

    Directory of Open Access Journals (Sweden)

    Christian Hendrich

    2009-12-01

    Full Text Available The clinical application of cellular based therapies with ex vivo cultivation for the treatment of diseases of the musculoskeletal system has until now been limited. In particular, the advanced laboratory and technical effort necessary, regulatory issues as well as high costs are major obstacles. On the other hand, newly developed cell therapy systems permit intra-operative enrichment and application of mesenchymal and progenitor stem cells from bone marrow aspirate concentrate (BMAC in one single operative session. The objective of the present clinical surveillance study was to evaluate new bone formation after the application of BMAC as well as to record any possible therapy-specific complications For this purpose, the clinical-radiological progress of a total of 101 patients with various bone healing disturbances was documented (surveillance study. The study included 37 necrosis of the head of the femur, 32 avascular necroses/bone marrow edema of other localization, 12 non-unions, 20 other defects. The application of BMAC was performed in the presence of osteonecrosis via a local injection as part of a core decompression (n=72 or by the local adsorption of intra-operative cellular bone substitution material (scaffold incubated with BMAC during osteosynthesis (n=17 or in further surgery (n=12. After an average of 14 months (2-24 months, the patients were re-examined clinically and radiologically and interviewed. Further surgery was necessary in 2 patients within the follow-up period. These were due to a progression of a collapsed head of the femur with initial necrosis in ARCO Stage III, as well as inadequate new bone formation with secondary loss of correction after periprosthetic femoral fracture. The latter healed after repeated osteosynthesis plus BMAC application without any consequences. Other than these 2 patients, no further complications were observed. In particular, no infections, no excessive new bone formation, no induction of

  20. Digital mammography using iodine-based contrast media: initial clinical experience with dynamic contrast medium enhancement.

    Science.gov (United States)

    Diekmann, Felix; Diekmann, Susanne; Jeunehomme, Fanny; Muller, Serge; Hamm, Bernd; Bick, Ulrich

    2005-07-01

    magnetic resonance imaging, as suggested by our initial results. The results are somewhat better when tumor enhancement relative to surrounding glandular tissue is used instead of absolute enhancement. The results of this preliminary study suggest that contrast-enhanced digital mammography is a potentially useful tool for the detection and the differentiation of benign and malignant breast lesions.

  1. "The refer less resolve more" initiative: A five-year experience from CMC Vellore, India

    Directory of Open Access Journals (Sweden)

    Jachin Velavan

    2012-01-01

    Full Text Available India′s one billion plus strong population presents huge health care needs. Presently, approximately 250,000 general practitioners and 30,000 Government doctors are a part of the Indian healthcare workforce, but 80% of them are based in urban India. Problems which plague healthcare delivery and attributed to physician practice may be enumerated as - physicians (1 lack competencies, (2 lack updating, (3 prescribe irrationally (pressures from pharmaceutical companies and patients, (4 practice unethically, (5 refer excessively to specialists and other clinical professionals, and (6 investigate for diseases without justification. A multi-competent Family Physician who could provide a single-window, ethical, and holistic healthcare to patients and families is the need of the hour. Therefore, training, equipping, and empowering these 250,000 doctors to become such physicians will reduce health costs considerably. Distance medical education using all the andragogic methods can be used to train large number of individuals without displacing them from their work-places. Distance learning provides a useful interface for rapidly developing a specialized pool of doctors practicing and advocating family medicine as most-needed discipline. This motivated CMC Vellore, a premier institution for medical education in India, to start a the "refer less resolve more initiative" by offering "two year family medicine diploma course" by distance mode. This is an innovatively-written program consisting of problem-based self-learning modules, video-lectures, video-conferencing, and face-to-face contact programs. Ten secondary level hospitals, across the country, under the supervision of national and international family medicine faculty form the pillars of this program. This distance learning program offered by CMC Vellore has become the platform for change as there is special focus is on ethics, rational prescribing, consultation skills, application of family medicine

  2. Experiment data report for Semiscale Mod-1 Test S-29-3; integral test from reduced initial pressure. [PWR

    Energy Technology Data Exchange (ETDEWEB)

    Crapo, H.S.; Collins, B.L.; Sackett, K.E.

    1976-09-01

    Recorded test data are presented for Test S-29-3 of the Semiscale Mod-1 special heat transfer test series. This test is among several Semiscale Mod-1 experiments conducted to investigate the thermal and hydraulic phenomena accompanying a hypothesized loss-of-coolant accident in a pressurized water reactor system. Test S-29-3 was conducted from an initial cold leg fluid temperature of 544/sup 0/F and an initial pressure of 1,760 psia. A simulated double-ended offset shear cold leg break was used to investigate the system response to a depressurization transient starting from a lower initial pressure than that usually associated with pressurized water reactor operation. System flow was set to achieve a full core fluid temperature differential of 66/sup 0/F at full core power of 1.6 MW. The flow resistance of the intact loop was based on core area scaling. An electrically heated core with a peaked radial power profile was used in the pressure vessel to simulate the effects of a nuclear core. During system depressurization, core power was reduced from the initial level of 1.6 MW to simulate the surface heat flux response of nuclear fuel rods until such time that departure from nucleate boiling might occur. Blowdown to the pressure suppression system was accompanied by simulated emergency core cooling injection into both the intact and broken loops. Coolant injection was continued until testtermination at 200 seconds after initiation of blowdown. The purpose of the report is to make available the uninterpreted data from Test S-29-3 for future data analysis and test results reporting activites. The data, presented in the form of graphs in engineering units, have been analyzed only to the extent necessary to assure that they are reasonable and consistent.

  3. Robotic pulmonary lobectomy for lung cancer treatment: program implementation and initial experience.

    Science.gov (United States)

    Terra, Ricardo Mingarini; Araujo, Pedro Henrique Xavier Nabuco de; Lauricella, Leticia Leone; Campos, José Ribas Milanez de; Costa, Herbert Felix; Pego-Fernandes, Paulo Manuel

    2016-01-01

    To describe the implementation of a robotic thoracic surgery program at a public tertiary teaching hospital and to analyze its initial results. This was a planned interim analysis of a randomized clinical trial aimed at comparing video-assisted thoracoscopic surgery and robotic surgery in terms of the results obtained after pulmonary lobectomy. The robotic surgery program developed at the Instituto do Câncer do Estado de São Paulo, in the city of São Paulo, Brazil, is a multidisciplinary initiative involving various surgical specialties, as well as anesthesiology, nursing, and clinical engineering teams. In this analysis, we evaluated the patients included in the robotic lobectomy arm of the trial during its first three months (from April to June of 2015). Ten patients were included in this analysis. There were eight women and two men. The mean age was 65.1 years. All of the patients presented with peripheral tumors. We performed right upper lobectomy in four patients, right lower lobectomy in four, and left upper lobectomy in two. Surgical time varied considerably (range, 135-435 min). Conversion to open surgery or video-assisted thoracoscopic surgery was not necessary in any of the cases. Intraoperative complications were not found. Only the first patient required postoperative transfer to the ICU. There were no deaths or readmissions within the first 30 days after discharge. The only postoperative complication was chest pain (grade 3), in two patients. Pathological examination revealed complete tumor resection in all cases. When there is integration and proper training of all of the teams involved, the implementation of a robotic thoracic surgery program is feasible and can reduce morbidity and mortality. Descrever a implantação de um programa de cirurgia torácica robótica em um hospital terciário público universitário e analisar seus resultados iniciais. Este estudo é uma análise interina planejada de um ensaio clínico aleatorizado cujo objetivo

  4. Cryoplasty for femoropopliteal arterial disease: late angiographic results of initial human experience.

    Science.gov (United States)

    Fava, Mario; Loyola, Soledad; Polydorou, Antonios; Papapavlou, Prodromos; Polydorou, Adamandia; Mendiz, Oscar; Joye, James D

    2004-11-01

    A new form of angioplasty, called cryoplasty, was developed to improve the late results typically associated with percutaneous transluminal angioplasty. Cryoplasty combines the dilation force of percutaneous transluminal angioplasty with the delivery of cold thermal energy to the vessel wall. This study reports the authors' early clinical experience with cryoplasty in patients with femoropopliteal disease. Fifteen patients with femoropopliteal arterial lesions were treated with cryoplasty (CryoVascular Systems, Los Gatos, CA). Cryoplasty was performed at 6 atm of pressure and delivered at -10 degrees C for 60 seconds. The ankle-brachial index (ABI) was measured at baseline, 24 hours after cryoplasty, and at 1 and 3 months during follow-up. Repeated angiography was performed at 6 and 18 months to determine short-term and late primary patency. Cryoplasty was technically successful in 93% of patients (< 30% residual stenosis and less then grade C dissection). ABIs at baseline were 0.64 +/- 0.08 and improved the day after cryoplasty to 0.95 +/- 0.09 (P < .05). ABIs were well maintained at 1 and 3 months with measurements of 0.94 +/- 0.09 and 0.92 +/- 0.10, respectively (P < .05 vs baseline). Baseline angiographic diameter stenosis improved significantly immediately following cryoplasty (86% +/- 12% to 16% +/- 3%; P < .05). Angiography at 6 months revealed 0% binary restenosis and insignificant change in residual stenosis from the acute cryoplasty results (16 +/- 3% vs 21 +/- 5%; P = NS). Late angiographic follow-up at 14 months +/- 4 demonstrated primary patency of 83.3%. Cryoplasty was able to achieve substantial dilation of femoropopliteal lesions with well-preserved late angiographic patency. Cryoplasty represents a potential advance in the field of endovascular medicine.

  5. Laparoscopic trans-mesocolic pyeloplasty in children: Initial experience from a center in India

    Directory of Open Access Journals (Sweden)

    Muneer Khan

    2011-01-01

    Full Text Available The aim of the present study is to report our experience with laparoscopic pyeloplasty via trans-mesocolic approach in children with left pelvi-ureteric junction (PUJ obstruction. Between May 2007 and May 2008, 12 children aged between five and 16 years, with documented PUJ obstruction on the left side, underwent laparoscopic pyeloplasty via trans-mesocolic approach. The outcome was assessed by post-operative isotope renal scan. The mean age of the study patients was eight years, ranging between five and 16 years. There were five males and seven females in the study. All children underwent Anderson Hynes Pyeloplasty by a single surgeon. All cases were stented with a JJ stent for a period of six weeks post-operatively. The procedures were completed successfully in all patients without need for conversion to open pyeloplasty in any patient. The mean operative time was 95 min, with a range of 80-140 min. The average blood loss was 57 mL. The mean hospital stay was 3.5 days with a range of 2.5 to six days. All children returned back to school within nine days following surgery. The mean follow-up period was 12 months (range, nine to 14 months. Eleven of the patients were completely asymptomatic, while one reported mild flank pain. All children underwent renal scans and renal ultrasound three months after stent removal. Ten had improved function on the scan while in one patient, the function remained the same and, in another, it showed obstructed response to diuretic, although the symptoms had improved. In all the cases, renal ultrasound showed a decrease in the severity of hydronephrosis by at least one degree. These results confirm that laparoscopic pyeloplasty by trans-mesocolic approach in children for left-sided PUJ obstruction is safe and feasible.

  6. Initial Validation of the Daily Spiritual Experiences Scale in Chinese Immigrants With Cancer Pain.

    Science.gov (United States)

    Lo, Graciete; Chen, Jack; Wasser, Thomas; Portenoy, Russell; Dhingra, Lara

    2016-02-01

    Evaluating religious/spiritual influences in the growing Chinese-American population may inform the development of culturally relevant palliative care interventions. We assessed the psychometric properties and acceptability of the Daily Spiritual Experiences Scale-Chinese (DSES-C) in Chinese Americans with cancer-related pain. The translated 16-item DSES-C was administered as part of a symptom intervention for Chinese-American cancer patients. Patients were recruited from four New York community oncology practices. Of 321 patients, 78.7% were born in Mainland China, 79.1% spoke Cantonese, and 70.2% endorsed a religious affiliation (Ancestor worship, 31.7%; Chinese God worship, 29.8%; Buddhism, 17.1%; Christianity, 14.0%). In total, 82.6% completed the DSES-C (mean age = 57.7 years; 60.8% women) and 17.4% declined (mean age = 59.3 years; 52.0% women). Reasons for declining included low religiosity or perceived relevance of the scale items and difficulties separating spirituality from religiosity terms. Individuals having a religious affiliation were more likely to complete the DSES-C, whereas those not engaging in individual spiritual/religious practices or frequent group spiritual/religious practices tended to decline (all P 0.40) across items except Item 14 ("Accept others"). Construct validity was suggested by a positive association between DSES-C scores and having a religious affiliation (P < 0.05). In Chinese Americans with cancer pain, the DSES-C demonstrated acceptable psychometrics. Some participants experienced linguistic or cultural barriers preventing completion. Future investigations should provide additional validation in different Asian subgroups and those with varied medical conditions. Copyright © 2016 American Academy of Hospice and Palliative Medicine. All rights reserved.

  7. MammaPrint Feasibility in a Large Tertiary Urban Medical Center: An Initial Experience

    Directory of Open Access Journals (Sweden)

    C. Francisco Espinel

    2012-01-01

    Full Text Available Background. The MammaPrint (MP diagnostic assay stratifies breast cancer patients into high- and low-risk groups using mRNA analysis of a 70-gene profile. The assay is validated for assessment of patients with estrogen receptor positive or negative tumors less than 5 cm with 3 or fewer malignant lymph nodes. TargetPrint (TP is an assay for assessing estrogen, progesterone, and HER2-neu receptor status based on mRNA expression. A potential limitation of these assays is that they require an evaluation of fresh tissue samples. There is limited published experience describing MP or TP implementation. Methods. Over 10 months, 4 breast surgeons obtained samples from 54 patients for MP/TP analysis. The samples were analyzed by Agendia Labs. The tumors were independently evaluated for receptor status using immunohistochemistry (IHC. Retrospectively, we identified patients who were assessed by MP/TP during this period. Patients who underwent OncotypeDx evaluation were also identified. Results. Of the 54 patients receiving MP, 4 were found ineligible for MP risk assessment because >3 lymph nodes were found to be malignant. Out of all eligible patients, 14/50 (28% had samples whose quantity of tumor was not sufficient for analysis (QNS. Out of eligible patients with tumors <1 cm, 7/8 (88% had QNS samples. 7/42 with tumors ≥1 cm (17% had QNS samples. Nine patients had discordant receptor results when evaluated by IHC versus. TP. Of patients who also underwent OncotypeDx testing, 6/14 (43% had discordant results with MP. Conclusions. This study indicates that using MP/TP assay is feasible in a tertiary care center but there may be utility in limiting MP testing to patients with tumors between 1 and 5 cm due to high likelihood of uninformative results in subcentimeter tumors. Further study is needed to explore the discordance between oncotype and MP results.

  8. Pan Eurasian Experiment (PEEX): a new research initiative focused on the Northern Pan-Eurasian Region

    Science.gov (United States)

    Petäjä, Tuukka; Lappalainen, Hanna; Zaytseva, Nina; Shvidenko, Anatoli; Kujansuu, Joni; Kerminen, Veli-Matti; Viisanen, Yrjö; Kotlyakov, Vladimir; Kasimov, Nikolai; Bondur, Valery; Matvienko, Gennadi; Zilitinkevich, Sergej; Kulmala, Markku

    2014-05-01

    The increasing human activities are changing the environment and the humanity is we are pushing the safe boundaries of the globe. It is of utmost importance to gauge with a comprehensive research program on the current status of the environment, particularly in the most vulnerable locations. Pan-Eurasian Experiment (PEEX) is a new multidisciplinary research approach aiming at resolving the major uncertainties in the Earth system science and global sustainability questions in the Arctic and boreal Pan-Eurasian regions. The PEEX program aims (i) to understand the Earth system and the influence of environmental and societal changes in pristine and industrialized Pan-Eurasian environments, (ii) to establish and sustain long-term, continuous and comprehensive ground-based airborne and seaborne research infrastructures, and to utilize satellite data and multi-scale model frameworks, (iii) to contribute to regional climate scenarios in the northern Pan-Eurasia and determine the relevant factors and interactions influencing human and societal wellbeing (iv) to promote the dissemination of PEEX scientific results and strategies in scientific and stake-holder communities and policy making, (v) to educate the next generation of multidisciplinary global change experts and scientists, and (vi) to increase the public awareness of climate change impacts in the Pan-Eurasian region. The development of PEEX research infrastructure will be one of the first activities of PEEX. PEEX will find synergies with the major European land-atmosphere observation infrastructures such as ICOS a research infrastructure to decipher the greenhouse gas balance of Europe and adjacent regions, ACTRIS (Aerosols, Clouds, and Trace gases Research InfraStructure Network-project), and ANAEE (The experimentation in terrestrial ecosystem research) networks and with the flag ship stations like the SMEARs (Station for Measuring Ecosystem-Atmosphere Relations) when design, re-organizing and networking existing

  9. Robotic-assisted modified retroauricular cervical approach: initial experience in Latin America.

    Science.gov (United States)

    Chulam, Thiago Celestino; Lira, Renan Bezerra; Kowalski, Luiz Paulo

    2016-01-01

    to evaluate the thickness of the gastric wall at the time of intra gastric balloon (IGB) placement, at the time of its withdrawal and one month after withdrawal. fifteen morbidly obese patients underwent the introduction of IGB under general anesthesia. In all patients, there was infusion of 500ml of distilled water in the balloon for the test. Measurements of the thickness of the gastric wall were made in the antrum, body and proximal body, using a radial echoendoscope with a frequency of 12MHz and maximum zoom, and its own balloon inflated with 5ml of distilled water. the presence of IGB led to increased wall thickness of the gastric body by expanding the muscle layer. These changes were apparently transient, since 30 days after the balloon withdrawal there was a tendency to return of the wall thickness values ​​observed before the balloon insertion. the use of intragastric balloon for the treatment of obesity determines transient increase in the wall thickness of the gastric body caused by expanded muscle layer. A preocupação com a melhoria dos resultados estéticos e funcionais sem comprometimento dos resultados oncológicos na cirurgia de cabeça e pescoço tem aumentado significativamente. Os procedimentos minimamente invasivos e principalmente aqueles que utilizam a tecnologia robótica permitiram o desenvolvimento de novas abordagens, incluindo o acesso retroauricular, que agora é usado rotineiramente, especialmente na Coréia do Sul. A presente nota irá ilustrar a técnica e a experiência inicial na América Latina, demonstrando que esta abordagem é viável, segura e eficaz oncologicamente, podendo ser utilizada em casos selecionados com um benefício estético evidente.

  10. Initial clinical experience with a high-definition exoscope system for microneurosurgery.

    Science.gov (United States)

    Mamelak, Adam N; Nobuto, Toshiko; Berci, George

    2010-08-01

    Advances in rigid-lens telescope systems provide an alternative method for magnification and illumination that may replace or supplement the operating microscope. To evaluate the clinical utility of an exoscope system as an alternative to the operating microscope. A custom-designed 10-mm-diameter rigid-lens telescope with a focal distance of 20 cm was attached to a 3-chip high-definition digital camera and displayed on a high-definition video monitor during surgery. A pneumatic scope holder positioned the scope over the operative field. This system was used in 16 procedures. The optical quality of the device was compared with that of an operating microscope during each procedure via a data entry form that evaluated optical quality, ease of manipulation, and overall ability to perform surgery. The high-definition exoscope was used in 9 craniotomies, 6 spinal procedures, and 1 neurostimulator placement. Image quality was almost equal to that of the operating microscope in all cases. Surgeons felt that the lack of stereopsis with a monitor-based system was compensated for with repeated procedures, but the absence of true 3-dimensional viewing limited use in some cases. Scope repositioning was not as easy as the operating microscope counterbalance mechanism, and focusing was more cumbersome. These relative limitations minimized as experience was accumulated. An exoscope has been developed for microneurosurgery with outstanding image quality and ease of manipulation that compares favorably with the microscope for many procedures. Refinement in the scope holder and the addition of 3-dimensional image display will improve user satisfaction. The current configuration is best suited for spinal neurosurgery and with refinement should have widespread application in neurosurgery.

  11. Initial experiments with the Nevis Cyclotron, the Brookhaven Cosmotron, the Brookhaven AGS and their effects on high energy physics

    Energy Technology Data Exchange (ETDEWEB)

    Lindenbaum, S.J.

    1988-01-01

    The first experiment at the Nevis Cyclotron by Bernardini, Booth and Lindenbaum demonstrated that nuclear stars are produced by a nucleon-nucleon cascade within the nucleon. This solved a long standing problem in Cosmic rays and made it clear that where they overlap cosmic ray investigation would not be competitive with accelerator investigations. The initial experiments at the Brookhaven Cosmotron by Lindenbaum and Yuan demonstrated that low energy pion nucleon scattering and pion production were unexpectedly mostly due to excitation of the isotopic spin = angular momentum = 3/2 isobaric state of the nucleon. This contradicted the Fermi statistical theory and led to the Isobar model proposed by the author and a collaborator. The initial experiments at the AGS by the author and collaborators demonstrated that the Pomeronchuck Theorem would not come true till at least several hundred GeV. These scattering experiments led to the development of the ''On-line Computer Technique'' by the author and collaborators which is now the almost universal technique in high energy physics. The first accomplishment which flowed from this technique led to contradiction of the Regge pole theory as a dynamical asymptotic theory, by the author and collaborators. The first critical experimental proof of the forward dispersion relation in strong interactions was accomplished by the author and collaborators. They were then used as a crystal ball to predict that ''Asymptopia''---the theoretically promised land where all asymptotic theorems come true---would not be reached till at least 25,000 BeV and probably not before 1,000,000 BeV. 26 refs., 11 figs., 2 tabs.

  12. Beginning software engineering

    CERN Document Server

    Stephens, Rod

    2015-01-01

    Beginning Software Engineering demystifies the software engineering methodologies and techniques that professional developers use to design and build robust, efficient, and consistently reliable software. Free of jargon and assuming no previous programming, development, or management experience, this accessible guide explains important concepts and techniques that can be applied to any programming language. Each chapter ends with exercises that let you test your understanding and help you elaborate on the chapter's main concepts. Everything you need to understand waterfall, Sashimi, agile, RAD, Scrum, Kanban, Extreme Programming, and many other development models is inside!

  13. Global Software Engineering

    DEFF Research Database (Denmark)

    Ebert, Christof; Kuhrmann, Marco; Prikladnicki, Rafael

    2016-01-01

    SOFTWARE, LIKE ALL industry products, is the result of complex multinational supply chains with many partners from concept to development to production and maintenance. Global software engineering (GSE), IT outsourcing, and business process outsourcing during the past decade have showed growth...... rates of 10 to 20 percent per year. This instalment of Practitioner’s Digest summarizes experiences and guidance from industry to facilitate knowledge and technology transfer for GSE. It’s based on industry feedback from the annual IEEE International Conference on Global Software Engineering, which had...

  14. Impact of Advanced Practice Registered Nurses on Quality Measures: The Missouri Quality Initiative Experience.

    Science.gov (United States)

    Rantz, Marilyn J; Popejoy, Lori; Vogelsmeier, Amy; Galambos, Colleen; Alexander, Greg; Flesner, Marcia; Murray, Cathy; Crecelius, Charles; Ge, Bin; Petroski, Gregory

    2017-12-02

    The purpose of this article is to review the impact of advanced practice registered nurses (APRNs) on the quality measure (QM) scores of the 16 participating nursing homes of the Missouri Quality Initiative (MOQI) intervention. The MOQI was one of 7 program sites in the US, with specific interventions unique to each site tested for the Centers for Medicaid and Medicare Services Innovations Center. While the goals of the MOQI for long-stay nursing home residents did not specifically include improvement of the QM scores, it was anticipated that improvement most likely would occur. Primary goals of the MOQI were to reduce the frequency of avoidable hospital admissions and readmissions; improve resident health outcomes; improve the process of transitioning between inpatient hospitals and nursing facilities; and reduce overall healthcare spending without restricting access to care or choice of providers. A 2-group comparison analysis was conducted using statewide QMs; a matched comparison group was selected from facilities in the same counties as the intervention homes, similar baseline QM scores, similar size and ownership. MOQI nursing homes each had an APRN embedded full-time to improve care and help the facility achieve MOQI goals. Part of their clinical work with residents and staff was to focus on quality improvement strategies with potential to influence healthcare outcomes. Trajectories of QM scores for the MOQI intervention nursing homes and matched comparison group homes were tested with nonparametric tests to examine for change in the desired direction between the 2 groups from baseline to 36 months. A composite QM score for each facility was constructed, and baseline to 36-month average change scores were examined using nonparametric tests. Then, adjusting for baseline, a repeated measures analysis using analysis of covariance as conducted. Composite QM scores of the APRN intervention group were significantly better (P = .025) than the comparison group

  15. Motion-Corrected Real-Time Cine Magnetic Resonance Imaging of the Heart: Initial Clinical Experience.

    Science.gov (United States)

    Rahsepar, Amir Ali; Saybasili, Haris; Ghasemiesfe, Ahmadreza; Dolan, Ryan S; Shehata, Monda L; Botelho, Marcos P; Markl, Michael; Spottiswoode, Bruce; Collins, Jeremy D; Carr, James C

    2018-01-01

    Free-breathing real-time (RT) imaging can be used in patients with difficulty in breath-holding; however, RT cine imaging typically experiences poor image quality compared with segmented cine imaging because of low resolution. Here, we validate a novel unsupervised motion-corrected (MOCO) reconstruction technique for free-breathing RT cardiac images, called MOCO-RT. Motion-corrected RT uses elastic image registration to generate a single heartbeat of high-quality data from a free-breathing RT acquisition. Segmented balanced steady-state free precession (bSSFP) cine images and free-breathing RT images (Cartesian, TGRAPPA factor 4) were acquired with the same spatial/temporal resolution in 40 patients using clinical 1.5 T magnetic resonance scanners. The respiratory cycle was estimated using the reconstructed RT images, and nonrigid unsupervised motion correction was applied to eliminate breathing motion. Conventional segmented RT and MOCO-RT single-heartbeat cine images were analyzed to evaluate left ventricular (LV) function and volume measurements. Two radiologists scored images for overall image quality, artifact, noise, and wall motion abnormalities. Intraclass correlation coefficient was used to assess the reliability of MOCO-RT measurement. Intraclass correlation coefficient showed excellent reliability (intraclass correlation coefficient ≥ 0.95) of MOCO-RT with segmented cine in measuring LV function, mass, and volume. Comparison of the qualitative ratings indicated comparable image quality for MOCO-RT (4.80 ± 0.35) with segmented cine (4.45 ± 0.88, P = 0.215) and significantly higher than conventional RT techniques (3.51 ± 0.41, P cine (1.51 ± 0.90, P = 0.088 and 1.23 ± 0.45, P = 0.182) were not different. Wall motion abnormality ratings were comparable among different techniques (P = 0.96). The MOCO-RT technique can be used to process conventional free-breathing RT cine images and provides comparable quantitative assessment of LV function and volume

  16. Initial Experiences of Transcatheter Aortic Valve Implantation (TAVI in Iran with Midterm Follow up

    Directory of Open Access Journals (Sweden)

    Ali Mohammad Haji Zeinali

    2017-09-01

    Functional Class (FC and Left Ventricle Ejection Fraction (LVEF from mean 43 ± 13.5 % preprocedural to 50.7 ± 7.8% within 6 months. Conclusions: Inoperable symptomatic senile valvular AS could be treated safely with TAVI. In- hospital results of the first sequential experience of TAVI in Tehran University of Medical Sciences were successful. TAVI in bicuspid AS and concomitant MR patients needs more caution in the procedure and follow up.

  17. Quantitative shear wave ultrasound elastography: initial experience in solid breast masses

    Science.gov (United States)

    2010-01-01

    Introduction Shear wave elastography is a new method of obtaining quantitative tissue elasticity data during breast ultrasound examinations. The aims of this study were (1) to determine the reproducibility of shear wave elastography (2) to correlate the elasticity values of a series of solid breast masses with histological findings and (3) to compare shear wave elastography with greyscale ultrasound for benign/malignant classification. Methods Using the Aixplorer® ultrasound system (SuperSonic Imagine, Aix en Provence, France), 53 solid breast lesions were identified in 52 consecutive patients. Two orthogonal elastography images were obtained of each lesion. Observers noted the mean elasticity values in regions of interest (ROI) placed over the stiffest areas on the two elastography images and a mean value was calculated for each lesion. A sub-set of 15 patients had two elastography images obtained by an additional operator. Reproducibility of observations was assessed between (1) two observers analysing the same pair of images and (2) findings from two pairs of images of the same lesion taken by two different operators. All lesions were subjected to percutaneous biopsy. Elastography measurements were correlated with histology results. After preliminary experience with 10 patients a mean elasticity cut off value of 50 kilopascals (kPa) was selected for benign/malignant differentiation. Greyscale images were classified according to the American College of Radiology (ACR) Breast Imaging Reporting and Data System (BI-RADS). BI-RADS categories 1-3 were taken as benign while BI-RADS categories 4 and 5 were classified as malignant. Results Twenty-three benign lesions and 30 cancers were diagnosed on histology. Measurement of mean elasticity yielded an intraclass correlation coefficient of 0.99 for two observers assessing the same pairs of elastography images. Analysis of images taken by two independent operators gave an intraclass correlation coefficient of 0.80. Shear

  18. Convergència digital i software lliure en l'EEES. Algunes experiències amb Gretl

    Directory of Open Access Journals (Sweden)

    Ana Jesús López Menéndez

    2012-12-01

    Full Text Available La utilització de programari lliure i obert (*FOSS aporta nombrosos avantatges en l'àmbit universitari, que resulten encara més patents en el marc de l'Espai Europeu d'Educació Superior (EEES. Les principals característiques del *FOSS (llibertat d'ús de programes, accés al codi font, estudi i adaptació, distribució de còpies i implementació de millores que beneficien a tota la comunitat apareixen relacionades amb competències com a creativitat, treball en equip o adaptació a noves situacions. Aquest treball examina el paper del programari lliure en l'àmbit universitari i el seu potencial per a reduir la bretxa digital, presentant també algunes experiències recents.

  19. The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization.

    Science.gov (United States)

    Morrell, William C; Birkel, Garrett W; Forrer, Mark; Lopez, Teresa; Backman, Tyler W H; Dussault, Michael; Petzold, Christopher J; Baidoo, Edward E K; Costello, Zak; Ando, David; Alonso-Gutierrez, Jorge; George, Kevin W; Mukhopadhyay, Aindrila; Vaino, Ian; Keasling, Jay D; Adams, Paul D; Hillson, Nathan J; Garcia Martin, Hector

    2017-12-15

    Although recent advances in synthetic biology allow us to produce biological designs more efficiently than ever, our ability to predict the end result of these designs is still nascent. Predictive models require large amounts of high-quality data to be parametrized and tested, which are not generally available. Here, we present the Experiment Data Depot (EDD), an online tool designed as a repository of experimental data and metadata. EDD provides a convenient way to upload a variety of data types, visualize these data, and export them in a standardized fashion for use with predictive algorithms. In this paper, we describe EDD and showcase its utility for three different use cases: storage of characterized synthetic biology parts, leveraging proteomics data to improve biofuel yield, and the use of extracellular metabolite concentrations to predict intracellular metabolic fluxes.

  20. Robust Software Architecture for Robots

    Science.gov (United States)

    Aghazanian, Hrand; Baumgartner, Eric; Garrett, Michael

    2009-01-01

    Robust Real-Time Reconfigurable Robotics Software Architecture (R4SA) is the name of both a software architecture and software that embodies the architecture. The architecture was conceived in the spirit of current practice in designing modular, hard, realtime aerospace systems. The architecture facilitates the integration of new sensory, motor, and control software modules into the software of a given robotic system. R4SA was developed for initial application aboard exploratory mobile robots on Mars, but is adaptable to terrestrial robotic systems, real-time embedded computing systems in general, and robotic toys.