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Sample records for exit wave reconstruction

  1. Exit wave reconstruction of radiation-sensitive materials from low-dose data

    Science.gov (United States)

    Huang, C.; Borisenko, K. B.; Kirkland, A. I.

    2014-06-01

    We report exit wave reconstruction using a focal series of low-dose images for ZSM-5, a zeolite which has a wide range of industrial applications. The exit wave phase was successfully reconstructed showing the structure of ZSM-5 at a near-atomic resolution even though the dose in the individual images in the focal series was as low as 26 electrons/Å2. This implementation shows the method's potential for application to other radiation-sensitive materials.

  2. Exitation of Whistler Waves by a Helical Wave Structure

    DEFF Research Database (Denmark)

    Balmashnov, A. A.; Lynov, Jens-Peter; Michelsen, Poul

    1981-01-01

    The excitation of whistler waves in a radial inhomogeneous plasma is investigated experimentally, using a slow-wave structure consisting of a helix of variable length surrounding the plasma column. The excited waves were observed to have a wave-vector parallel to the external magnetic field....... The possibility of exciting the waves in different radial regions is demonstrated....

  3. Unstable Electrostatic Ion Cyclotron Waves Exited by an Ion Beam

    DEFF Research Database (Denmark)

    Michelsen, Poul; Pécseli, Hans; Juul Rasmussen, Jens

    1976-01-01

    Electrostatic ion cyclotron waves were observed in a quiescent cesium plasma into which a low‐energy beam of sodium ions was injected. The instability appeared when the beam velocity was above 12 times the ion thermal velocity. The waves propagated along the magnetic field with a velocity somewhat...

  4. Thermographic image reconstruction using ultrasound reconstruction from virtual waves

    CERN Document Server

    Burgholzer, Peter; Gruber, Jürgen; Mayr, Günther

    2016-01-01

    Reconstruction of subsurface features from ultrasound signals measured on the surface is widely used in medicine and non-destructive testing. In this work, we introduce a concept how to use image reconstruction methods known from ultrasonic imaging for thermographic signals, i.e. on the measured temperature evolution on a sample surface. Before using these imaging methods a virtual signal is calculated by applying a transformation to the measured temperature evolution. The virtual signal is calculated locally for every detection point and has the same initial temperature distribution as the measured signal, but is a solution of the wave equation. The introduced transformation can be used for every shape of the detection surface and in every dimension. It describes all the irreversibility of the heat diffusion, which is responsible that the spatial resolution gets worse with increasing depth. Up to now, for thermographic imaging mostly one-dimensional methods, e.g., for depth-profiling were used, which are sui...

  5. Molecular state reconstruction by nonlinear wave packet interferometry.

    Science.gov (United States)

    Humble, Travis S; Cina, Jeffrey A

    2004-08-06

    We show that time- and phase-resolved two-color nonlinear wave packet interferometry can be used to reconstruct the probability amplitude of an optically prepared molecular wave packet without prior knowledge of the underlying potential surface. We analyze state reconstruction in pure- and mixed-state model systems excited by shaped laser pulses and propose nonlinear wave packet interferometry as a tool for identifying optimized wave packets in coherent control experiments.

  6. Probing the longitudinal momentum spread of the electron wave packet at the tunnel exit

    DEFF Research Database (Denmark)

    N. Pfeiffer, Adrian; Cirelli, Claudio; S. Landsman, Alexandra

    2012-01-01

    We present an ellipticity resolved study of momentum distributions arising from strong-field ionization of Helium at constant intensity. The influence of the ion potential on the departing electron is considered within a semi-classical model consisting of an initial tunneling step and subsequent ...... classical propagation. We find that the momentum distribution can be explained by the presence of a longitudinal momentum spread of the electron at the exit from the tunnel. Our combined experimental and theoretical study provides an estimate of this momentum spread....

  7. Towards nonlinear wave reconstruction and prediction from synthetic radar images

    NARCIS (Netherlands)

    Wijaya, Andreas Parama

    2016-01-01

    The use of remotely wave sensing by a marine radar is increasingly needed to provide wave information for the sake of safety and operational effectiveness in many offshore activities. Reconstruction of radar images needs to be carried out since radar images are a poor representation of the sea

  8. Wave-function reconstruction in a graded semiconductor superlattice

    DEFF Research Database (Denmark)

    Lyssenko, V. G.; Hvam, Jørn Märcher; Meinhold, D.

    2004-01-01

    We reconstruct a test wave function in a strongly coupled, graded well-width superlattice by resolving the spatial extension of the interband polarisation and deducing the wave function employing non-linear optical spectroscopy. The graded gap superlattice allows us to precisely control the dista...

  9. [Dynamic reconstruction of the fish locomotory wave].

    Science.gov (United States)

    Smolianinov, V V

    2009-01-01

    The inverse hydrodynamic task of the synthesis of a wave driver for aquatic organisms, in particular of fishes, has been solved. A multilink model of bending oscillations and the optimum phasings of transverse-rotary vibrations of parts was considered, which provides a maximum driving force of each link for two cases of the hydrodynamic interaction of the parts with water: the force of viscous resistance for a longitudinal and a transverse component of the vector of movement of a segment is proportional to (1) the speed of movement (linear friction) and (2) the square of speed (square-law friction). It was shown that the optimum phasings of link vibrations for transverse and rotary modes are strictly orthogonal for the variant of linear friction or are close to orthogonal in the case of square-law friction. The theoretical forms of the bending waves satisfying the dynamic optimization are compared to experimental data obtained earlier on the basis of filmregistration.

  10. Exit from inflation with a first-order phase transition and a gravitational wave blast

    Directory of Open Access Journals (Sweden)

    Amjad Ashoorioon

    2015-07-01

    Full Text Available In double-field inflation, which exploits two scalar fields, one of the fields rolls slowly during inflation whereas the other field is trapped in a meta-stable vacuum. The nucleation rate from the false vacuum to the true one becomes substantial enough that triggers a first order phase transition and ends inflation. We revisit the question of first order phase transition in an “extended” model of hybrid inflation, realizing the double-field inflationary scenario, and correctly identify the parameter space that leads to a first order phase transition at the end of inflation. We compute the gravitational wave profile which is generated during this first order phase transition. Assuming instant reheating, the peak frequency falls in the 1 GHz to 10 GHz frequency band and the amplitude varies in the range 10−11≲ΩGWh2≲10−8, depending on the value of the cosmological constant in the false vacuum. For a narrow band of vacuum energies, the first order phase transition can happen after the end of inflation via the violation of slow-roll, with a peak frequency that varies from 1 THz to 100 THz. For smaller values of cosmological constant, even though inflation can end via slow-roll violation, the universe gets trapped in a false vacuum whose energy drives a second phase of eternal inflation. This range of vacuum energies do not lead to viable inflationary models, unless the value of the cosmological constant is compatible with the observed value, M∼10−3 eV.

  11. Dense water cascading, bottom currents and sediment wave formation at the exit of the Bari canyon (Southern Adriatic Sea, Italy)

    Science.gov (United States)

    Langone, Leonardo; Miserocchi, Stefano; Boldrin, Alfredo; Turchetto, Margherita; Foglini, Federica; Trincardi, Fabio

    2010-05-01

    The dense water forming in the North Adriatic (NAdDW) spreading southward along the Italian continental shelf, sinks in the Southern Adriatic basin through particular cascading events. Such events are seasonal, occurring specially in April, with variable intensity. These phenomena control the water mass mixing, the deep ocean ventilation, the behaviour of deep ecosystems, the formation of complex erosive and depositional bedforms and the abyssal export and burial of nutrients and carbon. Because of the NadDW formation is linked to climate factors (frequency, duration and size of Bura winds), the temporal variations of the NadDW dispersion into the Southern Adriatic allow to make inferences of the impact of recent climate changes on the ecosystems of the deep Mediterranean Sea. Previous research projects (EuroStrataform, HERMES) acquired a large data set of bathymetric, side-scan sonar (TOBI) and Chirp sonar profiles, which were used to build detailed morpho-bathymetric maps of the Southern Adriatic margin. There, the seabed is extremely complex, characterized by a large variety of bedforms (sediment waves, erosive scours, longitudinal furrows and giant comet marks). A branch of the cascading NAdDW is confined and accelerated through the Bari canyon where it produces a strong current capable of reaching down-slope velocities greater than 60 cm s-1 near the bottom at ~600 m of water depth, eroding the canyon thalweg and entraining large amounts of fine-grained sediment. At the exit of the canyon, in water depth greater than 800 m, the current becomes less confined, spreads laterally and generates an 80-km2-wide field of mud waves; these bedforms migrate up current and show amplitudes up to 50 m and wavelengths of about 1 km. Cruise IMPACT-09 of RV Urania was carried out in the Southern Adriatic Sea from 17-30 March 2009 with main scope of studying the impact of NadDW cascading events on the deep ecosystems of the Southern Adriatic. Experiments planned in the cruise

  12. Iterative wave-front reconstruction in the Fourier domain.

    Science.gov (United States)

    Bond, Charlotte Z; Correia, Carlos M; Sauvage, Jean-François; Neichel, Benoit; Fusco, Thierry

    2017-05-15

    The use of Fourier methods in wave-front reconstruction can significantly reduce the computation time for large telescopes with a high number of degrees of freedom. However, Fourier algorithms for discrete data require a rectangular data set which conform to specific boundary requirements, whereas wave-front sensor data is typically defined over a circular domain (the telescope pupil). Here we present an iterative Gerchberg routine modified for the purposes of discrete wave-front reconstruction which adapts the measurement data (wave-front sensor slopes) for Fourier analysis, fulfilling the requirements of the fast Fourier transform (FFT) and providing accurate reconstruction. The routine is used in the adaptation step only and can be coupled to any other Wiener-like or least-squares method. We compare simulations using this method with previous Fourier methods and show an increase in performance in terms of Strehl ratio and a reduction in noise propagation for a 40×40 SPHERE-like adaptive optics system. For closed loop operation with minimal iterations the Gerchberg method provides an improvement in Strehl, from 95.4% to 96.9% in K-band. This corresponds to ~ 40 nm improvement in rms, and avoids the high spatial frequency errors present in other methods, providing an increase in contrast towards the edge of the correctable band.

  13. Exit Prostitution

    DEFF Research Database (Denmark)

    Henriksen, Theresa Dyrvig; Aslaug Kjær, Agnete; Christensen, Gunvor

    2015-01-01

    Dette midtvejsnotat omhandler projektet ”Exit prostitution”. Exit-projektet blev påbegyndt i april 2012 og løber til udgangen af 2015 og befinder sig i øjeblikket midtvejs i projektets afprøvningsfase. I projektet anvendes metoden Critical Time Intervention (CTI), der er en evidensbaseret...... til det. Exit-projektet er dermed en central socialpolitisk indsats overfor borgere i prostitution i det danske samfund. I dette notat belyser vi midtvejsresultater for, hvordan udviklingen er for de borgere, der er nået halvt igennem et CTI-forløb. I den afsluttende evaluering af projektet i 2015 vil...

  14. Exit prostitution

    DEFF Research Database (Denmark)

    Mehlsen, Line; Aslaug Kjær, Agnete; Amilon, Anna

    2016-01-01

    Dette statusnotat for projektet ”Exit Prostitution” belyser de foreløbige resultater og tendenser for projektet. Exit Prostitution løb oprindeligt fra april 2012 til udgangen af 2015, men med en nylig forlængelse løber projektet til udgangen af 2016. Projektet befinder sig således i slutningen af...... afprøvet med succes i forhold til hjemløshed både nationalt og internationalt. Målet med anvendelsen af metoden i forhold til målgruppen for Exit Prostitution er, at borgere med prostitutionserfaring, som ønsker at ophøre med salg af seksuelle ydelser eller ønsker at opleve en forbedring af deres...

  15. Extension of the modal wave-front reconstruction algorithm to non-uniform illumination.

    Science.gov (United States)

    Ma, Xiaoyu; Mu, Jie; Rao, ChangHui; Yang, Jinsheng; Rao, XueJun; Tian, Yu

    2014-06-30

    Attempts are made to eliminate the effects of non-uniform illumination on the precision of wave-front measurement. To achieve this, the relationship between the wave-front slope at a single sub-aperture and the distributions of the phase and light intensity of the wave-front were first analyzed to obtain the relevant theoretical formulae. Then, based on the principle of modal wave-front reconstruction, the influence of the light intensity distribution on the wave-front slope is introduced into the calculation of the reconstruction matrix. Experiments were conducted to prove that the corrected modal wave-front reconstruction algorithm improved the accuracy of wave-front reconstruction. Moreover, the correction is conducive to high-precision wave-front measurement using a Hartmann wave-front sensor in the presence of non-uniform illumination.

  16. Statistical reconstruction algorithms for continuous wave electron spin resonance imaging

    Science.gov (United States)

    Kissos, Imry; Levit, Michael; Feuer, Arie; Blank, Aharon

    2013-06-01

    Electron spin resonance imaging (ESRI) is an important branch of ESR that deals with heterogeneous samples ranging from semiconductor materials to small live animals and even humans. ESRI can produce either spatial images (providing information about the spatially dependent radical concentration) or spectral-spatial images, where an extra dimension is added to describe the absorption spectrum of the sample (which can also be spatially dependent). The mapping of oxygen in biological samples, often referred to as oximetry, is a prime example of an ESRI application. ESRI suffers frequently from a low signal-to-noise ratio (SNR), which results in long acquisition times and poor image quality. A broader use of ESRI is hampered by this slow acquisition, which can also be an obstacle for many biological applications where conditions may change relatively quickly over time. The objective of this work is to develop an image reconstruction scheme for continuous wave (CW) ESRI that would make it possible to reduce the data acquisition time without degrading the reconstruction quality. This is achieved by adapting the so-called "statistical reconstruction" method, recently developed for other medical imaging modalities, to the specific case of CW ESRI. Our new algorithm accounts for unique ESRI aspects such as field modulation, spectral-spatial imaging, and possible limitation on the gradient magnitude (the so-called "limited angle" problem). The reconstruction method shows improved SNR and contrast recovery vs. commonly used back-projection-based methods, for a variety of simulated synthetic samples as well as in actual CW ESRI experiments.

  17. Inertia-gravity waves in the troposphere and lower stratosphere associated with a jet stream exit region

    Directory of Open Access Journals (Sweden)

    L. Thomas

    Full Text Available Radar measurements at Aberystwyth (52.4° N, 4.1° W of winds at tropospheric and lower stratospheric heights are shown for 12-13 March 1994 in a region of highly curved flow, downstream of the jet maximum. The perturbations of horizontal velocity have comparable amplitudes in the troposphere and lower stratosphere with downward and upward phase propagation, respectively, in these two height regions. The sense of rotation with increasing height in hodographs of horizontal perturbation velocity derived for hourly intervals show downwards propagation of energy in the troposphere and upward propagation in the lower stratosphere with vertical wavelengths of 1.7 to 2.3 km. The results indicate inertia-gravity waves propagating in a direction similar to that of the jet stream but at smaller velocities. Some of the features observed contrast with those of previous observations of inertia-gravity waves propagating transverse to the jet stream. The interpretation of the hodographs to derive wave parameters has taken account of the vertical shear of the background wind transverse to the direction of wave propagation.

    Key words. Meteorology and atmospheric dynamics (mesoscale meteorology; middle atmosphere dynamics; waves and tides

  18. Virgo calibration and reconstruction of the gravitationnal wave strain during VSR1

    NARCIS (Netherlands)

    Accadia, T.; Bauer, Th. S.; Beker, M.G.; Bulten, H.J.; Rabeling, D.S.; van den Brand, J.F.J.; van der Putten, S.

    2010-01-01

    Virgo is a kilometer-length interferometer for gravitationnal waves detection located near Pisa. Its first science run, VSR1, occured from May to October 2007. The aims of the calibration are to measure the detector sensitivity and to reconstruct the time series of the gravitationnal wave strain

  19. Sound field reconstruction within an entire cavity by plane wave expansions using a spherical microphone array.

    Science.gov (United States)

    Wang, Yan; Chen, Kean

    2017-10-01

    A spherical microphone array has proved effective in reconstructing an enclosed sound field by a superposition of spherical wave functions in Fourier domain. It allows successful reconstructions surrounding the array, but the accuracy will be degraded at a distance. In order to extend the effective reconstruction to the entire cavity, a plane-wave basis in space domain is used owing to its non-decaying propagating characteristic and compared with the conventional spherical wave function method in a low frequency sound field within a cylindrical cavity. The sensitivity to measurement noise, the effects of the numbers of plane waves, and measurement positions are discussed. Simulations show that under the same measurement conditions, the plane wave function method is superior in terms of reconstruction accuracy and data processing efficiency, that is, the entire sound field imaging can be achieved by only one time calculation instead of translations of local sets of coefficients with respect to every measurement position into a global one. An experiment was conducted inside an aircraft cabin mock-up for validation. Additionally, this method provides an alternative possibility to recover the coefficients of high order spherical wave functions in a global coordinate system without coordinate translations with respect to local origins.

  20. Object wave reconstruction by speckle illumination and phase retrieval

    DEFF Research Database (Denmark)

    Almoro, Percival; Hanson, Steen Grüner

    2009-01-01

    An innovative setup for the speckle-based phase retrieval method is proposed. In the conventional setup, a plane wave illuminates the test object and the transmitted wavefront is incident on a diffuser aperture generating a speckle field. The sampled speckle intensities at axially displaced planes...... are input into a phase retrieval algorithm based on a wave propagation equation. In the new setup, the arrangement of the diffuser and the object is reversed. A plane wave incident on the diffuser generates a speckle field which, in turn, is used to illuminate the object. The transmitted wavefront...

  1. Reconstruction of surface waves using super virtual interferometry: an example from the Forsmark site, Sweden

    Science.gov (United States)

    Xu, Zhuo; Juhlin, Christopher; Han, Liguo; Zhang, Fengjiao

    2017-10-01

    Seismic interferometry is a technique that enables the extraction of the seismic impulse response (Green's function) between two receivers. The retrieved response is generally dominated by surface waves when sources are located at or near the surface of the Earth. In onshore seismic exploration, dealing with complex near-surface conditions is one of the main challenges for seismic data processing. In some cases, seismic interferometry can be used for suppressing surface waves without the use of a priori near-surface velocity model. Aside from being an effective tool for surface wave attenuation, the reconstructed surface waves generated by seismic interferometry contain useful information about near-surface heterogeneities and can be used to characterize the near-surface velocity field. In this study, we apply super virtual interferometry (SVI) to a real onshore data set from the Forsmark site, central Sweden, with the primary aim of characterizing shallow-subsurface structure. This is accomplished by improving the dispersion characteristics of the surface waves. We also show that SVI performs better than conventional correlation-type and convolution-type interferometry when reconstructing surface waves, both in synthetic and real data. We use the dispersive behaviour of the reconstructed surface waves to infer the geological structure of the shallow subsurface.

  2. Image reconstruction for optical tomography using photon density waves

    Energy Technology Data Exchange (ETDEWEB)

    Khalaf, R

    1999-08-01

    Diagnostic imaging makes use of different kinds of radiation. A recent type of imaging using near-infrared light is thought to be a safer and less-expensive method of in-vivo imaging. Near infra-red light can penetrate biological tissue to certain depths. The problem of using near infrared light for imaging, is that the scattering of the photons dominates absorption, causing difficulties in the reconstruction model on which biomedical optical imaging depends crucially. The aim of this thesis is to develop and investigate the performance of a reconstruction algorithm in the frequency domain which allows fast and efficient reconstruction of the image of a limb, or an optical phantom. The forward problem of the propagation of photons inside biological tissue is modelled using the Diffusion Approximation theory solved by the finite element method. Values of DC intensity, phase shift and modulation depth at the boundary as functions of the diffusion and absorption coefficients are given. The inverse model is formulated as a nonlinear least-squares optimisation problem. The Truncated Newton method with Trust region is used to determine the optical properties. Reverse differentiation is used to calculate the error function because of its speed advantage over forward differentiation. A sensitivity analysis is performed to investigate the simultaneous reconstruction of the diffusion and absorption coefficients. The use of a combined error function of DC intensity, phase and modulation prove to be the most successful at recovering the optical parameters. The ability to distinguish between object size and size of optical parameter is also investigated. Contrast, mean and standard deviation are used as measures of the performance of the reconstruction algorithm. A Tikhonov regularisation method was used to improve ill-conditioning and behaviour in the presence of noise. An investigation of the optimal regularisation parameter is undertaken with the addition of noise to the

  3. Reconstructing three-dimensional reentrant cardiac electrical wave dynamics using data assimilation

    Science.gov (United States)

    Hoffman, M. J.; LaVigne, N. S.; Scorse, S. T.; Fenton, F. H.; Cherry, E. M.

    2016-01-01

    For many years, reentrant scroll waves have been predicted and studied as an underlying mechanism for cardiac arrhythmias using numerical techniques, and high-resolution mapping studies using fluorescence recordings from the surfaces of cardiac tissue preparations have confirmed the presence of visible spiral waves. However, assessing the three-dimensional dynamics of these reentrant waves using experimental techniques has been limited to verifying stable scroll-wave dynamics in relatively thin preparations. We propose a different approach to recovering the three-dimensional dynamics of reentrant waves in the heart. By applying techniques commonly used in weather forecasting, we combine dual-surface observations from a particular experiment with predictions from a numerical model to reconstruct the full three-dimensional time series of the experiment. Here, we use model-generated surrogate observations from a numerical experiment to evaluate the performance of the ensemble Kalman filter in reconstructing such time series for a discordant alternans state in one spatial dimension and for scroll waves in three dimensions. We show that our approach is able to recover time series of both observed and unobserved variables matching the truth. Where nearby observations are available, the error is reduced below the synthetic observation error, with a smaller reduction with increased distance from observations. Our findings demonstrate that state reconstruction for spatiotemporally complex cardiac electrical dynamics is possible and will lead naturally to applications using real experimental data.

  4. Reconstruction of Interfering Waves from Three Dimensional Analysis of Their Interference Pattern

    Directory of Open Access Journals (Sweden)

    M. T. Tavassoli

    1997-04-01

    Full Text Available   Optical interferometry is being used as an efficient tool to analyse smooth surfaces for more than a century. Although, due to introduction of novel computer assisted analyzing techniques and array detectors, like CCD, the speed and the precision of processing have been increased tremendously, but the main equation involved is not changed. The main equation is the intensity distribution in the interference pattern of a plane reference wave and the required wave.   In the paper it is shown that by analysis of the interference pattern of two unknown waves in three dimension (which is possible for coherent waves it is possible to reconstruct each wave separately. This approach has several useful applications, namely, on can do without reference plane wave in the interferometric surface analysis and, it is possible to reconstruct an unknown wave by making it to interfere with itself. This is very useful in determining the profile of laser beams and erasing the effect of atmospheric disturbances on observing astronomical objects.

  5. On the comparsion of the Spherical Wave Expansion-to-Plane Wave Expansion and the Sources Reconstruction Method for Antenna Diagnostics

    DEFF Research Database (Denmark)

    Alvarez, Yuri; Cappellin, Cecilia; Las-Heras, Fernando

    2008-01-01

    A comparison between two recently developed methods for antenna diagnostics is presented. On one hand, the Spherical Wave Expansion-to-Plane Wave Expansion (SWE-PWE), based on the relationship between spherical and planar wave modes. On the other hand, the Sources Reconstruction Method (SRM), based...

  6. WASS: An open-source pipeline for 3D stereo reconstruction of ocean waves

    Science.gov (United States)

    Bergamasco, Filippo; Torsello, Andrea; Sclavo, Mauro; Barbariol, Francesco; Benetazzo, Alvise

    2017-10-01

    Stereo 3D reconstruction of ocean waves is gaining more and more popularity in the oceanographic community and industry. Indeed, recent advances of both computer vision algorithms and computer processing power now allow the study of the spatio-temporal wave field with unprecedented accuracy, especially at small scales. Even if simple in theory, multiple details are difficult to be mastered for a practitioner, so that the implementation of a sea-waves 3D reconstruction pipeline is in general considered a complex task. For instance, camera calibration, reliable stereo feature matching and mean sea-plane estimation are all factors for which a well designed implementation can make the difference to obtain valuable results. For this reason, we believe that the open availability of a well tested software package that automates the reconstruction process from stereo images to a 3D point cloud would be a valuable addition for future researches in this area. We present WASS (http://www.dais.unive.it/wass), an Open-Source stereo processing pipeline for sea waves 3D reconstruction. Our tool completely automates all the steps required to estimate dense point clouds from stereo images. Namely, it computes the extrinsic parameters of the stereo rig so that no delicate calibration has to be performed on the field. It implements a fast 3D dense stereo reconstruction procedure based on the consolidated OpenCV library and, lastly, it includes set of filtering techniques both on the disparity map and the produced point cloud to remove the vast majority of erroneous points that can naturally arise while analyzing the optically complex nature of the water surface. In this paper, we describe the architecture of WASS and the internal algorithms involved. The pipeline workflow is shown step-by-step and demonstrated on real datasets acquired at sea.

  7. Multichannel filtering and reconstruction of ultrasonic guided wave fields using time intercept-slowness transform.

    Science.gov (United States)

    Tran, Tho N H T; Le, Lawrence H; Sacchi, Mauricio D; Nguyen, Vu-Hieu; Lou, Edmond H M

    2014-07-01

    Multichannel ultrasonic axial-transmission data are multimodal by nature. As guided waves are commonly used in nondestructive material testing, wave field filtering becomes important because the analysis is usually limited to a few lower-order modes and requires their extraction. An application of the Radon transform to enhance signal-to-noise ratio and separate wave fields in ultrasonic records is presented. The method considers guided wave fields as superpositions of plane waves defined by ray parameters (p) and time intercepts (τ) and stacks the amplitudes along linear trajectories, mapping time-offset (t - x) data to a τ - p or Radon panel. The transform is implemented using a least-squares strategy with Cauchy-norm regularization that serves to enhance the focusing power. The method was verified using simulated data and applied to an uneven spatially sampled bovine-bone-plate data set. The results demonstrate the Radon panels show isolated amplitude clusters and the Cauchy-norm constraint provides a more focused Radon image than the damped least-squares regularization. Wave field separation can be achieved by selectively windowing the τ - p signals and inverse transformation, which is illustrated by the successful extraction of the A0 mode in bone plate. In addition, the method effectively attenuates noise, enhances the coherency of the guided wave modes, and reconstructs the missing records. The proposed transform presents a powerful signal-enhancement tool to process guided waves for further analysis and inversion.

  8. Reconstruction of Casimir—Polder interactions from matter-wave interference experiments

    Science.gov (United States)

    Fiedler, Johannes; Broer, Wijnand; Scheel, Stefan

    2017-08-01

    Interference of matter waves at nanostructures has been studied in a variety of experiments to explore the quantum nature of atoms, molecules and clusters. The detection process typically focuses on an amplitude measurement of the matter wave. However, more information can be gained about the physical mechanism behind the scattering process at the nanostructure by also investigating the phase properties of the matter wave. Measurement devices for the wavefront, known as Hartmann-Shack sensors, rely on a lens array to refocus the wavefront onto a screen and to detect lateral deviations of the focal position. Here we show that the construction of a similar device is possible for matter waves. In particular, we propose an experiment where the Casimir-Polder potential between a small polarisable particle and the nanostructure is reconstructed by measuring both the amplitude in a conventional set-up and the wavefront in a Hartmann-Shack configuration.

  9. Virgo calibration and reconstruction of the gravitationnal wave strain during VSR1

    Energy Technology Data Exchange (ETDEWEB)

    Accadia, T; Belletoile, A [Laboratoire d' Annecy-le-Vieux de Physique des Particules (LAPP), IN2P3/CNRS, Universite de Savoie, F-74941 Annecy-le-Vieux (France); Arun, K G; Bizouard, M A [LAL, Universite Paris-Sud, IN2P3/CNRS, F-91898 Orsay (France); Ballardin, G [European Gravitational Observatory (EGO), 1-56021 Cascina (Italy); Barsuglia, M [AstroParticule et Cosmologie (APC), CNRS: UMR7164-IN2P3-Observatoire de Paris-Universite Denis Diderot-Paris 7 - CEA : DSM/IRFU (France); Boccara, C [ESPCI, CNRS, F-75005 Paris (France); Acernese, F; Antonucci, F; Aoudia, S; Astone, P; Barone, F; Bauer, Th S; Beker, M G; Bigotta, S; Birindelli, S; Bitossi, M; Blom, M; Bondu, F; Bonelli, L, E-mail: rollandl@in2p3.f

    2010-05-01

    Virgo is a kilometer-length interferometer for gravitationnal waves detection located near Pisa. Its first science run, VSR1, occured from May to October 2007. The aims of the calibration are to measure the detector sensitivity and to reconstruct the time series of the gravitationnal wave strain h(t). The absolute length calibration is based on an original non-linear reconstruction of the differential arm length variations in free swinging Michelson configurations. It uses the laser wavelength as length standard. This method is used to calibrate the frequency dependent response of the Virgo mirror actuators and derive the detector in-loop response and sensitivity within {approx} 5%. The principle of the strain reconstruction is highlighted and the h(t) systematic errors are estimated. A photon calibrator is used to check the sign of h(t). The reconstructed h(t) during VSR1 is valid from 10 Hz up to 10 kHz with systematic errors estimated to 6% in amplitude. The phase error is estimated to be 70 mrad below 1.9 kHz and 6 {mu}s above.

  10. One step linear reconstruction method for continuous wave diffuse optical tomography

    Science.gov (United States)

    Ukhrowiyah, N.; Yasin, M.

    2017-09-01

    The method one step linear reconstruction method for continuous wave diffuse optical tomography is proposed and demonstrated for polyvinyl chloride based material and breast phantom. Approximation which used in this method is selecting regulation coefficient and evaluating the difference between two states that corresponding to the data acquired without and with a change in optical properties. This method is used to recovery of optical parameters from measured boundary data of light propagation in the object. The research is demonstrated by simulation and experimental data. Numerical object is used to produce simulation data. Chloride based material and breast phantom sample is used to produce experimental data. Comparisons of results between experiment and simulation data are conducted to validate the proposed method. The results of the reconstruction image which is produced by the one step linear reconstruction method show that the image reconstruction almost same as the original object. This approach provides a means of imaging that is sensitive to changes in optical properties, which may be particularly useful for functional imaging used continuous wave diffuse optical tomography of early diagnosis of breast cancer.

  11. TSUNAMI LEAD WAVE RECONSTRUCTION BASED ON NOISY SEA SURFACE HEIGHT MEASUREMENTS

    Directory of Open Access Journals (Sweden)

    K. Yu

    2016-06-01

    Full Text Available This paper presents a Tsunami lead wave reconstruction method using noisy sea surface height (SSH measurements such as observed by a satellite-carried GNSS reflectometry (GNSS-R sensor. It is proposed to utilize wavelet theory to mitigate the strong noise in the GNSS-R based SSH measurements. Through extracting the noise components by high-pass filters at decomposition stage and shrinking the noise by thresholding prior to reconstruction, the noise is greatly reduced. Real Tsunami data based simulation results demonstrate that in presence of SSH measurement error of standard deviation 50 cm the accuracy in terms of root mean square error (RMSE of the lead wave height (true value 145.5 cm and wavelength (true value 592.0 km estimation is 21.5 cm and 56.2 km, respectively. The results also show that the proposed wavelet based method considerably outperforms the Kalman filter based method on average. The results demonstrate that the proposed wave reconstruction approach has the potential for Tsunami detection and parameter estimation to assist in achieving reliable Tsunami warning.

  12. Reconstruction of Initial Wave Field of a Nonsteady-State Wave Propagation from Limited Measurements at a Specific Spatial Point Based on Stochastic Inversion

    Directory of Open Access Journals (Sweden)

    S. L. Han

    2013-01-01

    Full Text Available This paper studies an inverse problem that can be used for reconstructing initial wave field of a nonsteady-state wave propagation. The inverse problem is ill posed in the sense that small changes in the input data can greatly affect the solution of the problem. To address the difficulty, the problem is formulated in the form of an inference problem in an appropriately constructed stochastic model. It is shown that the stochastic inverse model enables the initial surface disturbance to be reconstructed, including its confidence intervals given the noisy measurements. The reconstruction procedure is illustrated through applications to some simulated data for two- and three-dimensional problem.

  13. Exit by Afghanisation

    DEFF Research Database (Denmark)

    Holmberg, Hasse

    USA’s exit-strategi fra Afghanistan har båret præg af et italesat hovedmål om overdragelse af ansvar til de nationale myndigheder i landet. Exit-strategien udmærker sig ved sin lighed med USA’s afvikling af sit engagement i Vietnam for snart et halvt århundrede siden, hvor begrebet Vietnamisation...... at nærme sig svaret på dette spørgsmål via en komparativ analyse af de to amerikanske exit-startegier i henholdsvis Vietnam og Afghanistan....

  14. Reconstruction of nonstationary sound fields based on the time domain plane wave superposition method.

    Science.gov (United States)

    Zhang, Xiao-Zheng; Thomas, Jean-Hugh; Bi, Chuan-Xing; Pascal, Jean-Claude

    2012-10-01

    A time-domain plane wave superposition method is proposed to reconstruct nonstationary sound fields. In this method, the sound field is expressed as a superposition of time convolutions between the estimated time-wavenumber spectrum of the sound pressure on a virtual source plane and the time-domain propagation kernel at each wavenumber. By discretizing the time convolutions directly, the reconstruction can be carried out iteratively in the time domain, thus providing the advantage of continuously reconstructing time-dependent pressure signals. In the reconstruction process, the Tikhonov regularization is introduced at each time step to obtain a relevant estimate of the time-wavenumber spectrum on the virtual source plane. Because the double infinite integral of the two-dimensional spatial Fourier transform is discretized directly in the wavenumber domain in the proposed method, it does not need to perform the two-dimensional spatial fast Fourier transform that is generally used in time domain holography and real-time near-field acoustic holography, and therefore it avoids some errors associated with the two-dimensional spatial fast Fourier transform in theory and makes possible to use an irregular microphone array. The feasibility of the proposed method is demonstrated by numerical simulations and an experiment with two speakers.

  15. WASS: an open-source stereo processing pipeline for sea waves 3D reconstruction

    Science.gov (United States)

    Bergamasco, Filippo; Benetazzo, Alvise; Torsello, Andrea; Barbariol, Francesco; Carniel, Sandro; Sclavo, Mauro

    2017-04-01

    Stereo 3D reconstruction of ocean waves is gaining more and more popularity in the oceanographic community. In fact, recent advances of both computer vision algorithms and CPU processing power can now allow the study of the spatio-temporal wave fields with unprecedented accuracy, especially at small scales. Even if simple in theory, multiple details are difficult to be mastered for a practitioner so that the implementation of a 3D reconstruction pipeline is in general considered a complex task. For instance, camera calibration, reliable stereo feature matching and mean sea-plane estimation are all factors for which a well designed implementation can make the difference to obtain valuable results. For this reason, we believe that the open availability of a well-tested software package that automates the steps from stereo images to a 3D point cloud would be a valuable addition for future researches in this area. We present WASS, a completely Open-Source stereo processing pipeline for sea waves 3D reconstruction, available at http://www.dais.unive.it/wass/. Our tool completely automates the recovery of dense point clouds from stereo images by providing three main functionalities. First, WASS can automatically recover the extrinsic parameters of the stereo rig (up to scale) so that no delicate calibration has to be performed on the field. Second, WASS implements a fast 3D dense stereo reconstruction procedure so that an accurate 3D point cloud can be computed from each stereo pair. We rely on the well-consolidated OpenCV library both for the image stereo rectification and disparity map recovery. Lastly, a set of 2D and 3D filtering techniques both on the disparity map and the produced point cloud are implemented to remove the vast majority of erroneous points that can naturally arise while analyzing the optically complex nature of the water surface (examples are sun-glares, large white-capped areas, fog and water areosol, etc). Developed to be as fast as possible, WASS

  16. Globally accelerated reconstruction algorithm for diffusion tomography with continuous-wave source in an arbitrary convex shape domain.

    Science.gov (United States)

    Pantong, Natee; Su, Jianzhong; Shan, Hua; Klibanov, Michael V; Liu, Hanli

    2009-03-01

    A new numerical imaging algorithm is presented for reconstruction of optical absorption coefficients from near-infrared light data with a continuous-wave source. As a continuation of our earlier efforts in developing a series of methods called "globally convergent reconstruction methods" [J. Opt. Soc. Am. A23, 2388 (2006)], this numerical algorithm solves the inverse problem through solution of a boundary-value problem for a Volterra-type integral partial differential equation. We deal here with the particular issues in solving the inverse problems in an arbitrary convex shape domain. It is demonstrated in numerical studies that this reconstruction technique is highly efficient and stable with respect to the complex distribution of actual unknown absorption coefficients. The method is particularly useful for reconstruction from a large data set obtained from a tissue or organ of particular shape, such as the prostate. Numerical reconstructions of a simulated prostate-shaped phantom with three different settings of absorption-inclusions are presented.

  17. Urban shear-wave reflection seismics: Reconstruction support by combined shallow seismic and engineering geology investigations

    Science.gov (United States)

    Polom, U.; Guenther, A.; Arsyad, I.; Wiyono, P.; Krawczyk, C. M.

    2009-12-01

    After the big 2004 Sumatra-Andaman earthquake, the massive reconstruction activities in the Aceh province (Northern Sumatra) were promoted by the Republic of Indonesia and the Federal Ministry of Economic Cooperation and Development. The aims of the project MANGEONAD (Management of Georisk Nanggroe Aceh Darussalam). are to establish geoscientific on the ground support for a sustainable development and management of save building constructions, lifelines, infrastructure and also natural resources. Therefore, shallow shear-wave reflection seismics was applied in close combination to engineering geology investigations in the period between 2005-2009 since depth and internal structure of the Krueng Aceh River delta (mainly young alluvial sediments) were widely unknown. Due to the requirements in the densely populated Banda Aceh region, lacking also traffic infrastructure, a small and lightweight engineering seismic setup of high mobility and high subsurface resolution capability was chosen. The S-wave land streamer system with 48 channels was applied successfully together with the ELVIS vibratory source using S- and P-waves on paved roads within the city of Banda Aceh. The performance of the S-wave system enabled the detailed seismic investigation of the shallow subsurface down to 50-150 m depth generating shaking frequencies between 20 Hz to 200 Hz. This also provides depth information extending the maximum depths of boreholes and Standard Penetrometer Testings (SPT), which could only be applied to max. 20 m depth. To integrate the results gained from all three methods, and further to provide a fast statistical analysis tool for engineering use, the Information System Engineering Geology (ISEG, BGR) was developed. This geospatial information tool includes the seismic data, all borehole information, geotechnical SPT and laboratory results from samples available in the investigation area. Thereby, the geotechnical 3D analysis of the subsurface units is enabled. The

  18. Effects of model error on cardiac electrical wave state reconstruction using data assimilation.

    Science.gov (United States)

    LaVigne, Nicholas S; Holt, Nathan; Hoffman, Matthew J; Cherry, Elizabeth M

    2017-09-01

    Reentrant electrical scroll waves have been shown to underlie many cardiac arrhythmias, but the inability to observe locations away from the heart surfaces and the restriction of observations to only one or two state variables have made understanding arrhythmia mechanisms challenging. Recently, we showed that data assimilation from spatiotemporally sparse surrogate observations could be used to reconstruct a reliable time series of state estimates of reentrant cardiac electrical waves including unobserved variables in one and three spatial dimensions. However, real cardiac tissue is unlikely to be described accurately by mathematical models because of errors in model formulation and parameterization as well as intrinsic but poorly described spatial heterogeneity of electrophysiological properties in the heart. Here, we extend our previous work to assess how model error affects the accuracy of cardiac state estimates achieved using data assimilation with the Local Ensemble Transform Kalman Filter. We focus on one-dimensional states of discordant alternans characterized by significant wavelength oscillations. We demonstrate that data assimilation can provide high-quality estimates under a wide range of model error conditions, ranging from varying one or more parameter values to using an entirely different model to generate the truth state. We illustrate how multiplicative and additive inflation can be used to reduce error in the state estimates. Even when the truth state contains underlying spatial heterogeneity, we show that using a homogeneous model in the data assimilation algorithm can achieve good results. Overall, we find data assimilation to be a robust approach for reconstructing complex cardiac electrical states corresponding to arrhythmias even in the presence of model error.

  19. Effects of model error on cardiac electrical wave state reconstruction using data assimilation

    Science.gov (United States)

    LaVigne, Nicholas S.; Holt, Nathan; Hoffman, Matthew J.; Cherry, Elizabeth M.

    2017-09-01

    Reentrant electrical scroll waves have been shown to underlie many cardiac arrhythmias, but the inability to observe locations away from the heart surfaces and the restriction of observations to only one or two state variables have made understanding arrhythmia mechanisms challenging. Recently, we showed that data assimilation from spatiotemporally sparse surrogate observations could be used to reconstruct a reliable time series of state estimates of reentrant cardiac electrical waves including unobserved variables in one and three spatial dimensions. However, real cardiac tissue is unlikely to be described accurately by mathematical models because of errors in model formulation and parameterization as well as intrinsic but poorly described spatial heterogeneity of electrophysiological properties in the heart. Here, we extend our previous work to assess how model error affects the accuracy of cardiac state estimates achieved using data assimilation with the Local Ensemble Transform Kalman Filter. We focus on one-dimensional states of discordant alternans characterized by significant wavelength oscillations. We demonstrate that data assimilation can provide high-quality estimates under a wide range of model error conditions, ranging from varying one or more parameter values to using an entirely different model to generate the truth state. We illustrate how multiplicative and additive inflation can be used to reduce error in the state estimates. Even when the truth state contains underlying spatial heterogeneity, we show that using a homogeneous model in the data assimilation algorithm can achieve good results. Overall, we find data assimilation to be a robust approach for reconstructing complex cardiac electrical states corresponding to arrhythmias even in the presence of model error.

  20. Reconstruction of the gravity wave field from convective plumes via ray tracing

    Directory of Open Access Journals (Sweden)

    S. L. Vadas

    2009-01-01

    Full Text Available We implement gravity wave (GW phases into our convective plume and anelastic ray trace models. This allows us to successfully reconstruct the GW velocity, temperature, and density perturbation amplitudes and phases in the Mesosphere-Lower-Thermosphere (MLT via ray tracing (in real space those GWs that are excited from a deep convective plume. We find that the ray trace solutions agree very well with the exact, isothermal, zero-wind, Fourier-Laplace solutions in the Boussinesq limit. This comparison also allows us to determine the normalization factor which converts the GW spectral amplitudes to real-space amplitudes in the ray trace model. This normalization factor can then be used for ray tracing GWs through varying temperature and wind profiles. We show that by adding GW reflection off the Earth's surface, the resulting GW spectrum has more power at larger vertical and horizontal wavelengths. We determine the form of the momentum flux and velocity spectra which allows for easy calculation of GW amplitudes in the MLT and thermosphere. Finally, we find that the reconstructed (ray traced solution for a deep, convective plume with a duration much shorter than the buoyancy period does not equal the Fourier-Laplace Boussinesq solution; this is likely due to errors in the Boussinesq dispersion relation for very high frequency GWs.

  1. See-through Detection and 3D Reconstruction Using Terahertz Leaky-Wave Radar Based on Sparse Signal Processing

    Science.gov (United States)

    Murata, Koji; Murano, Kosuke; Watanabe, Issei; Kasamatsu, Akifumi; Tanaka, Toshiyuki; Monnai, Yasuaki

    2018-02-01

    We experimentally demonstrate see-through detection and 3D reconstruction using terahertz leaky-wave radar based on sparse signal processing. The application of terahertz waves to radar has received increasing attention in recent years for its potential to high-resolution and see-through detection. Among others, the implementation using a leaky-wave antenna is promising for compact system integration with beam steering capability based on frequency sweep. However, the use of a leaky-wave antenna poses a challenge on signal processing. Since a leaky-wave antenna combines the entire signal captured by each part of the aperture into a single output, the conventional array signal processing assuming access to a respective antenna element is not applicable. In this paper, we apply an iterative recovery algorithm "CoSaMP" to signals acquired with terahertz leaky-wave radar for clutter mitigation and aperture synthesis. We firstly demonstrate see-through detection of target location even when the radar is covered with an opaque screen, and therefore, the radar signal is disturbed by clutter. Furthermore, leveraging the robustness of the algorithm against noise, we also demonstrate 3D reconstruction of distributed targets by synthesizing signals collected from different orientations. The proposed approach will contribute to the smart implementation of terahertz leaky-wave radar.

  2. Exit-strategies

    DEFF Research Database (Denmark)

    Mørck, Line Lerche; Palm, Anne-Mette; Sys Møller-Andersen, Camilla

    to the diversity of the involved communities. This includes movements beyond thinking in dichotomies of either being criminal, ex-criminal or not criminal. 2) As pointed in the quote above, expanding conditions for exit is also about ending the gang-war, which includes police intervention and negotiations between...... the involved parties.  3) Development of effective social work with youngsters at risk of getting involved in the gang conflict. In Denmark we have a strong tradition for doing social work with ethnic minority youth, and good practice which is about to be developed further into more geographic areas. But we...

  3. Reanalysis of the 1893 heat wave in France through offline data assimilation in a downscaled ensemble meteorological reconstruction

    Science.gov (United States)

    Devers, Alexandre; Vidal, Jean-Philippe; Lauvernet, Claire; Graff, Benjamin

    2017-04-01

    The knowledge of historical French weather has recently been improved through the development of the SCOPE (Spatially COherent Probabilistic Extended) Climate reconstruction, a probabilistic high-resolution daily reconstruction of precipitation and temperature covering the period 1871-2012 and based on the statistical downscaling of the Twentieth Century Reanalysis (Caillouet et al., 2016). However, historical surface observations - even though rather scarce and sparse - do exist from at least the beginning of the period considered, and this information does not currently feed SCOPE Climate reconstructions. The goal of this study is therefore to assimilate these historical observations into SCOPE Climate reconstructions in order to build a 150-year meteorological reanalysis over France. This study considers "offline" data assimilation methods - Kalman filtering methods like the Ensemble Square Root Filter - that have successfully been used in recent paleoclimate studies, i.e. at much larger temporal and spatial scales (see e.g. Bhend et al., 2012). These methods are here applied for reconstructing the 8-24 August 1893 heat wave in France, using all available daily temperature observations from that period. Temperatures reached that summer were indeed compared at the time to those of Senegal (Garnier, 2012). Results show a spatially coherent view of the heat wave at the national scale as well as a reduced uncertainty compared to initial meteorological reconstructions, thus demonstrating the added value of data assimilation. In order to assess the performance of assimilation methods in a more recent context, these methods are also used to reconstruct the well-known 3-14 August 2003 heat wave by using (1) all available stations, and (2) the same station density as in August 1893, the rest of the observations being saved for validation. This analysis allows comparing two heat waves having occurred 100 years apart in France with different associated uncertainties, in

  4. Promoting Exit from Violent Extremism

    DEFF Research Database (Denmark)

    Dalgaard-Nielsen, Anja

    2013-01-01

    a perspective on how these natural sources of doubt might best be brought to bear in connection with an exit program by drawing on social psychology and research into persuasion and attitude change. It is argued that an external intervention should stay close to the potential exiter’s own doubt, make......A number of Western countries are currently adding exit programs targeting militant Islamists to their counterterrorism efforts. Drawing on research into voluntary exit from violent extremism, this article identifies themes and issues that seem to cause doubt, leading to exit. It then provides...

  5. Signal reconstruction of surface waves on SASW measurement using Gaussian Derivative wavelet transform

    Science.gov (United States)

    Rosyidi, Sri; Taha, Mohd; Chik, Zamri; Ismail, Amiruddin

    2009-09-01

    Surface wave method consists of measurement and processing of the dispersive Rayleigh waves recorded from two or more vertical transducers. The dispersive phase data are inverted and the shear wave velocity versus depth is obtained. However, in case of residual soil, the reliable phase spectrum curve is difficult to be produced. Noises from nature and other human-made sources disturb the generated surface wave data. In this paper, a continuous wavelet transform based on mother wavelet of Gaussian Derivative was used to analyze seismic waves in different frequency and time. Time-frequency wavelet spectrum was employed to localize the interested seismic response spectrum of generated surface waves. It can also distinguish the fundamental mode of the surface wave from the higher modes of reflected body waves. The results presented in this paper showed that the wavelet analysis is able to determine reliable surface wave spectrum of sandy clayey residual soil.

  6. Innovation and venture capital exits

    NARCIS (Netherlands)

    Schwienbacher, A.

    2008-01-01

    This article analyses how start-ups financed by venture capital choose their innovation strategy based on the investor's exit preferences and thereby form different outcomes in the product market. It considers innovation choices and venture capital exits (IPO vs trade sale) in a setting in which

  7. Exits from Temporary Jobs in Europe: A Competing Risks Analysis

    DEFF Research Database (Denmark)

    D'Addio, Anna Christina; Rosholm, Michael

    2005-01-01

    We study transitions out of temporary jobs using the waves 1994-1999 of the European Community Household Panel applying a discrete time duration model. Specifically, we use a multinomial logitmodel distinguishing between exits into permanent employment and non-employment. Two different specificat......We study transitions out of temporary jobs using the waves 1994-1999 of the European Community Household Panel applying a discrete time duration model. Specifically, we use a multinomial logitmodel distinguishing between exits into permanent employment and non-employment. Two different...

  8. Technological Progress, Exit and Trade

    DEFF Research Database (Denmark)

    Schröder, Philipp; Sørensen, Allan

    The dynamics of export market exit and firm closure have found limited attention in heterogeneous-firms trade models. Accordingly, several of the predictions on exit stemming from new-new trade theory are at odds with the stylized facts. Empirically, higher productivity firms survive longer, higher...... productivity exporters are more likely to continue to export, and market exit is typically preceded by periods of contracting market shares. We show that the simple inclusion of exogenous economy wide technological progress into the standard Melitz (2003) model generates a tractable dynamic framework...

  9. Simulations for design and reconstruction of breaking waves in a wavetank

    NARCIS (Netherlands)

    Kurnia, Ruddy; van den Munckhof, T.; Poot, C.P.; Naaijen, P.; Huijsmans, R.H.M.; van Groesen, Embrecht W.C.

    To determine forces on fixed and flexible structures such as wind mills and oil platforms, experiments in wave tanks are useful to investigate the impacts in various types of environmental waves. In this paper we show that the use of an efficient simulation code can optimize the experiments by

  10. PCR, exit stage left ...

    CERN Multimedia

    2004-01-01

    The Prevessin Control Room during LEP's start up in 1989. The Prévessin Control Room (PCR) was recently engulfed in a wave of nostalgia. The PCR, scene of some of the greatest moments in CERN's history, is being dismantled to prepare for a complete overhaul. In February 2006, a new combined control centre for all the accelerators will open its doors on the same site, together with a new building currently under construction (see Bulletin issue 27/2004 of 28 June 2004). This marks the end of an important chapter in CERN's history. The Prévessin Control Room saw its first momentous event 28 years ago when the 400 GeV beam for the SPS was commissioned in the presence of Project Leader John Adams. It was also here that the first proton-antiproton collisions were observed, in 1981. Eight years later, in 1989, operators and directors alike jumped for joy at the announcement of the first electron-positron collisions at the start up of LEP, the biggest accelerator in the world. Today the 80 terminals and PCs have b...

  11. Super-resolution image reconstruction applied to an active millimeter wave imaging system based on compressive sensing

    Science.gov (United States)

    Alkuş, Ümit; Şengün Ermeydan, Esra; Şahin, Asaf Behzat; ćankaya, Ä.°lyas; Altan, Hakan

    2017-10-01

    The development of passive and active millimeter wave imaging systems is progressing rapidly fueled by the need for many applications in the area of security and defense. Imaging schemes that may either utilize array detectors or single detectors in scan architectures offer suffer from poor resolution due to the longer wavelengths used and the limits of the optical system in terms of lens and mirror dimensions. In order to overcome this limit, super-resolution techniques can be employed to enhance the resolution of the imaging system. Here, a form of this technique based on oversampling is applied to reconstruct the image of a target which is acquired using compressive sensing based on scanning the image plane using randomly patterned masks with fixed pixel sizes. The mm-wave stand-off imaging system uses a 93 GHz center frequency source and heterodyne sub-harmonic receiver place in a bi-static configuration to image a target in reflection mode. The image of the target is projected onto a mechanically scanned spatial light modulator (SLM), which is a patterned two-dimensional mask that is translated along one axis. In order to improve the resolution of the image, the masks are shifted by half the pixel size (2.5mm). To enhance the resolution of the image, the patterns are shifted by smaller steps, thereby each pixel is oversampled and the resulting new pattern and detected intensity is fed into the CS algorithm to reconstruct the image of the target. After the image reconstruction process, sharper edges are observed for a circular object of 12mm diameter compared to the image acquired by whole pixel step scanning.

  12. Structural Health Monitoring Using Lamb Wave Reflections and Total Focusing Method for Image Reconstruction

    OpenAIRE

    Muller, Aurelia; Robertson Welsh, Bradley; Gaydecki, Patrick; Gresil, Matthieu; Soutis, Constantinos

    2017-01-01

    This investigation aimed to adapt the total focusing method (TFM) algorithm (originated form the synthetic aperture technique in digital signal processing) to accommodate a circular array of piezoelectric sensors (PZT) and characterise defects using guided wave signals for the development of a structural health monitoring system. This research presents the initial results of a broader research focusing on the development of a structural health monitoring guided wave system for advance carbon ...

  13. Mutual Fund Exit and Mutual Fund Fees

    OpenAIRE

    Philip C. English II; Ilhan Demiralp; William P. Dukes

    2011-01-01

    We examine the effect of mutual fund fee structure on mutual fund exit mode and timing. The evidence presented herein is consistent with fee maximization by mutual fund sponsors or managers, increased conflicts of interest for funds charging 12b-1 fees and higher management fees, and a pecking order for mutual fund exit method. Specifically, mutual fund exits that result in decreased fee income are delayed relative to exits that do not and exit strategies that retain fee income are more likel...

  14. Structural Health Monitoring Using Lamb Wave Reflections and Total Focusing Method for Image Reconstruction

    Science.gov (United States)

    Muller, Aurelia; Robertson-Welsh, Bradley; Gaydecki, Patrick; Gresil, Matthieu; Soutis, Constantinos

    2017-04-01

    This investigation aimed to adapt the total focusing method (TFM) algorithm (originated from the synthetic aperture focusing technique in digital signal processing) to accommodate a circular array of piezoelectric sensors (PZT) and characterise defects using guided wave signals for the development of a structural health monitoring system. This research presents the initial results of a broader study focusing on the development of a structural health monitoring (SHM) guided wave system for advance carbon fibre reinforced plastic (CFRP) composite materials. The current material investigated was an isotropic (aluminium) square plate with 16 transducers operating successively as emitter or sensor in pitch and catch configuration enabling the collection of 240 signals per assessment. The Lamb wave signals collected were tuned on the symmetric fundamental mode with a wavelength of 17 mm, by setting the excitation frequency to 300 kHz. The initial condition for the imaging system, such as wave speed and transducer position, were determined with post processing of the baseline signals through a method involving the identification of the waves reflected from the free edge of the plate. The imaging algorithm was adapted to accommodate multiple transmitting transducers in random positions. A circular defect of 10 mm in diameter was drilled in the plate, which is similar to the delamination size introduced by a low velocity impact event in a composite plate. Images were obtained by applying the TFM to the baseline signals, Test 1 data (corresponding to the signals obtained after introduction of the defect) and to the data derived from the subtraction of the baseline to the Test 1 signals. The result shows that despite the damage diameter being 40 % smaller than the wavelength, the image (of the subtracted baseline data) demonstrated that the system can locate where the waves were reflected from the defect boundary. In other words, the contour of the damaged area was

  15. Multigrid preconditioned conjugate-gradient method for large-scale wave-front reconstruction.

    Science.gov (United States)

    Gilles, Luc; Vogel, Curtis R; Ellerbroek, Brent L

    2002-09-01

    We introduce a multigrid preconditioned conjugate-gradient (MGCG) iterative scheme for computing open-loop wave-front reconstructors for extreme adaptive optics systems. We present numerical simulations for a 17-m class telescope with n = 48756 sensor measurement grid points within the aperture, which indicate that our MGCG method has a rapid convergence rate for a wide range of subaperture average slope measurement signal-to-noise ratios. The total computational cost is of order n log n. Hence our scheme provides for fast wave-front simulation and control in large-scale adaptive optics systems.

  16. Reconstruction and deterministic prediction of ocean waves from synthetic radar images

    NARCIS (Netherlands)

    Wijaya, Andreas Parama

    2017-01-01

    A marine X-band radar is a device that scans the surrounding ocean waves up to distances of some 2 km. A rotating antenna emits electromagnetic beams that are reflected at the water surface and partly received by the antenna and stored as intensity plots every radar rotation time. The coverage of a

  17. First Degree Pacemaker Exit Block

    Directory of Open Access Journals (Sweden)

    Johnson Francis

    2016-10-01

    Full Text Available Usually atrial and ventricular depolarizations follow soon after the pacemaker stimulus (spike on the ECG. But there can be an exit block due to fibrosis at the electrode - tissue interface at the lead tip. This can increase the delay between the spike and atrial or ventricular depolarization.

  18. LACE Project Exit Action Plan

    NARCIS (Netherlands)

    Drachsler, Hendrik; Scheffel, Maren

    2016-01-01

    This document describes a series of practical actions to secure long-term impact for LACE project outputs and to conserve community momentum beyond the project end. In this deliverable, we provide a first version of an exit and sustainability plan that covers key issues central to the exploitation

  19. Dispersive Magnetosonic Waves and Turbulence in the Heliosheath: Multi-Fluid MHD Reconstruction of Voyager 2 Observations

    Science.gov (United States)

    Zieger, B.; Opher, M.; Toth, G.

    2016-12-01

    Recently we demonstrated that our three-fluid MHD model of the solar wind plasma (where cold thermal solar wind ions, hot pickup ions, and electrons are treated as separate fluids) is able to reconstruct the microstructure of the termination shock observed by Voyager 2 [Zieger et al., 2015]. We constrained the unknown pickup ion abundance and temperature and confirmed the presence of a hot electron population at the termination shock, which has been predicted by a number of previous theoretical studies [e.g. Chasei and Fahr, 2014; Fahr et al., 2014]. We showed that a significant part of the upstream hydrodynamic energy is transferred to the heating of pickup ions and "massless" electrons. As shown in Zieger et al., [2015], three-fluid MHD theory predicts two fast magnetosonic modes, a low-frequency fast mode or solar wind ion (SW) mode and a high-frequency fast mode or pickup ion (PUI) mode. The coupling of the two ion populations results in a quasi-stationary nonlinear mode or oscilliton, which appears as a trailing wave train downstream of the termination shock. In single-fluid plasma, dispersive effects appear on the scale of the Debye length. However, in a non-equilibrium plasma like the solar wind, where solar wind ions and PUIs have different temperatures, dispersive effects become important on fluid scales [see Zieger et al., 2015]. Here we show that the dispersive effects of fast magnetosonic waves are expected on the scale of astronomical units (AU), and dispersion plays an important role producing compressional turbulence in the heliosheath. The trailing wave train of the termination shock (the SW-mode oscilliton) does not extend to infinity. Downstream propagating PUI-mode waves grow until they steepen into PUI shocklets and overturn starting to propagate backward. The upstream propagating PUI-mode waves result in fast magnetosonic turbulence and limit the downstream extension of the oscilliton. The overturning distance of the PUI-mode, where these waves

  20. Reconstruction of the first-derivative EPR spectrum from multiple harmonics of the field-modulated continuous wave signal.

    Science.gov (United States)

    Tseitlin, Mark; Eaton, Sandra S; Eaton, Gareth R

    2011-04-01

    Selection of the amplitude of magnetic field modulation for continuous wave electron paramagnetic resonance (EPR) often is a trade-off between sensitivity and resolution. Increasing the modulation amplitude improves the signal-to-noise ratio, S/N, at the expense of broadening the signal. Combining information from multiple harmonics of the field-modulated signal is proposed as a method to obtain the first derivative spectrum with minimal broadening and improved signal-to-noise. The harmonics are obtained by digital phase-sensitive detection of the signal at the modulation frequency and its integer multiples. Reconstruction of the first-derivative EPR line is done in the Fourier conjugate domain where each harmonic can be represented as the product of the Fourier transform of the 1st derivative signal with an analytical function. The analytical function for each harmonic can be viewed as a filter. The Fourier transform of the 1st derivative spectrum can be calculated from all available harmonics by solving an optimization problem with the goal of maximizing the S/N. Inverse Fourier transformation of the result produces the 1st derivative EPR line in the magnetic field domain. The use of modulation amplitude greater than linewidth improves the S/N, but does not broaden the reconstructed spectrum. The method works for an arbitrary EPR line shape, but is limited to the case when magnetization instantaneously follows the modulation field, which is known as the adiabatic approximation. Copyright © 2011 Elsevier Inc. All rights reserved.

  1. Reconstructing the Sky Location of Gravitational-Wave Detected Compact Binary Systems: Methodology for Testing and Comparison

    Science.gov (United States)

    Sidney, T.; Aylott, B.; Christensen, N.; Farr, B.; Farr, W.; Feroz, F.; Gair, J.; Grover, K.; Graff, P.; Hanna, C.; hide

    2014-01-01

    The problem of reconstructing the sky position of compact binary coalescences detected via gravitational waves is a central one for future observations with the ground-based network of gravitational-wave laser interferometers, such as Advanced LIGO and Advanced Virgo. Different techniques for sky localization have been independently developed. They can be divided in two broad categories: fully coherent Bayesian techniques, which are high latency and aimed at in-depth studies of all the parameters of a source, including sky position, and "triangulation-based" techniques, which exploit the data products from the search stage of the analysis to provide an almost real-time approximation of the posterior probability density function of the sky location of a detection candidate. These techniques have previously been applied to data collected during the last science runs of gravitational-wave detectors operating in the so-called initial configuration. Here, we develop and analyze methods for assessing the self consistency of parameter estimation methods and carrying out fair comparisons between different algorithms, addressing issues of efficiency and optimality. These methods are general, and can be applied to parameter estimation problems other than sky localization. We apply these methods to two existing sky localization techniques representing the two above-mentioned categories, using a set of simulated inspiralonly signals from compact binary systems with a total mass of equal to or less than 20M solar mass and nonspinning components. We compare the relative advantages and costs of the two techniques and show that sky location uncertainties are on average a factor approx. equals 20 smaller for fully coherent techniques than for the specific variant of the triangulation-based technique used during the last science runs, at the expense of a factor approx. equals 1000 longer processing time.

  2. Efficient Reconstruction of CAS-CI-Type Wave Functions for a DMRG State Using Quantum Information Theory and a Genetic Algorithm.

    Science.gov (United States)

    Luo, Zhen; Ma, Yingjin; Liu, Chungen; Ma, Haibo

    2017-10-10

    We improve the methodology to construct a complete active space-configuration interaction (CAS-CI) expansion for density-matrix renormalization group (DMRG) wave functions using a matrix-product state representation, inspired by the sampling-reconstructed CAS [SR-CAS; Boguslawski , K. ; J. Chem. Phys. 2011 , 134 , 224101 ] algorithm. In our scheme, the genetic algorithm, in which the "crossover" and "mutation" processes can be optimized based on quantum information theory, is employed when reconstructing a CAS-CI-type wave function in the Hilbert space. Analysis of results for ground and excited state wave functions of conjugated molecules, transition metal compounds, and a lanthanide complex illustrate that our scheme is very efficient for searching the most important CI expansions in large active spaces.

  3. Multinationals and plant exit: evidence from Chile

    OpenAIRE

    Álvarez Espinoza, Roberto; Görg, Holger

    2005-01-01

    This paper examines the link between multinational enterprises and plant exit in Chile. We investigate three main questions: are affiliates of foreign multinationals more likely to exit than domestic firms? Does the exit probability of multinationals depend on its export orientation?, and Does the presence of multinationals affect the survival of other firms in the economy? Our results show that foreign plants are more likely to exit the economy, controlling for other firm and industry charac...

  4. Exit Exam as Academic Performance Indicator

    Science.gov (United States)

    Al Ahmad, Mahmoud; Al Marzouqi, Ali H.; Hussien, Mousa

    2014-01-01

    This paper focuses on the impact of exit exams on different elements of the educational process, namely: curriculum development, students and instructors. A 50-question multiple-choice Exit Exam was prepared by Electrical Engineering (EE) faculty members covering a poll of questions from EE core courses. A copy of the Exit Exam applied during each…

  5. 14 CFR 23.807 - Emergency exits.

    Science.gov (United States)

    2010-01-01

    ... opening measuring not less than 19 inches by 26 inches high with corner radii not greater than one-third the width of the exit, located over the wing, with a step up inside the airplane of not more than 29... width of the exit, and with a step up inside the airplane of not more than 20 inches. If the exit is...

  6. Exit Planning At Joost El

    DEFF Research Database (Denmark)

    Nellemann, Camilla

    2017-01-01

    This is a Danish version. This case focuses on an owner-manager's considerations regarding his exit. Carsten Joost established Joost El in 2005. It currently employs 10 people. He has two sons but no intention to hand over the business to them. Rather, he hopes that his key employee eventually...... will take over Joost El. However, if he receives an offer from a buyer who can pay a higher price than the employee, Carsten Joost will have to sell the company at the highest price while knowing that doing so will disappoint his employee. The reason is that Carsten Joost has no pension. The question is how...

  7. Block-sparse reconstruction and imaging for Lamb wave structural health monitoring.

    Science.gov (United States)

    Levine, Ross M; Michaels, Jennifer E

    2014-06-01

    A frequently investigated paradigm for monitoring the integrity of plate-like structures is a spatially-distributed array of piezoelectric transducers, with each array element capable of both transmitting and receiving ultrasonic guided waves. This configuration is relatively inexpensive and allows interrogation of defects from multiple directions over a relatively large area. Typically, full sets of pairwise transducer signals are acquired by exciting one transducer at a time in a round-robin fashion. Many algorithms that operate on such data use differential signals that are created by subtracting prerecorded baseline signals, leaving only signal differences introduced by scatterers. Analysis methods such as delay-and-sum imaging operate on these signals to detect and locate point-like defects, but such algorithms have limited performance and suffer when potential scatterers have high directionality or unknown phase-shifting behavior. Signal envelopes are commonly used to mitigate the effects of unknown phase shifts, but this further reduces performance. The blocksparse technique presented here uses a different principle to locate damage: each pixel is assumed to have a corresponding multidimensional linear scattering model, allowing any possible amplitude and phase shift for each transducer pair should a scatterer be present. By assuming that the differential signals are linear combinations of a sparse subset of these models, it is possible to split such signals into location-based components. Results are presented here for three experiments using aluminum and composite plates, each with a different type of scatterer. The scatterers in these images have smaller spot sizes than delay-and-sum imaging, and the images themselves have fewer artifacts. Although a propagation model is required, block-sparse imaging performs well even with a small number of transducers or without access to dispersion curves.

  8. Calcium Signaling and Meiotic Exit at Fertilization in Xenopus Egg

    Science.gov (United States)

    Tokmakov, Alexander A.; Stefanov, Vasily E.; Iwasaki, Tetsushi; Sato, Ken-Ichi; Fukami, Yasuo

    2014-01-01

    Calcium is a universal messenger that mediates egg activation at fertilization in all sexually reproducing species studied. However, signaling pathways leading to calcium generation and the mechanisms of calcium-induced exit from meiotic arrest vary substantially among species. Here, we review the pathways of calcium signaling and the mechanisms of meiotic exit at fertilization in the eggs of the established developmental model, African clawed frog, Xenopus laevis. We also discuss calcium involvement in the early fertilization-induced events in Xenopus egg, such as membrane depolarization, the increase in intracellular pH, cortical granule exocytosis, cortical contraction, contraction wave, cortical rotation, reformation of the nuclear envelope, sperm chromatin decondensation and sister chromatid segregation. PMID:25322156

  9. Entrepreneurial Exit in Real and Imagined Markets

    NARCIS (Netherlands)

    E. Stam (Erik); A.R. Thurik (Roy); P.W. van der Zwan (Peter)

    2008-01-01

    textabstractEntrepreneurs exit their business due to selection mechanisms experienced in the market place. Next to this well known ex-post decision to exit, entrepreneurs select ex-ante whether they are willing to pursue an entrepreneurial career at all, or to give up these entrepreneurial

  10. 14 CFR 25.807 - Emergency exits.

    Science.gov (United States)

    2010-01-01

    ..., with landing gear extended. (6) Tailcone. This type is an aft exit from the passenger compartment... adverse exit opening condition that would result from the collapse of one or more legs of the landing gear... the top of the opening not less than 56 inches from the passenger compartment floor, 15 additional...

  11. Exit strategies for social venture entrepreneurs

    NARCIS (Netherlands)

    Nuer, A.T.K.

    2015-01-01

    Key Words:  Social Venture Entrepreneurs, Exit, Ownership Social Venture Entrepreneurs invest in local and mostly bottom of pyramid (BoPs), and more so in developing economies. Different understanding  and meanings given to the term  exit and ownership, by social venture entrepreneurs

  12. Wave

    DEFF Research Database (Denmark)

    Ibsen, Lars Bo

    2008-01-01

    Estimates for the amount of potential wave energy in the world range from 1-10 TW. The World Energy Council estimates that a potential 2TW of energy is available from the world’s oceans, which is the equivalent of twice the world’s electricity production. Whilst the recoverable resource is many...... times smaller it remains very high. For example, whilst there is enough potential wave power off the UK to supply the electricity demands several times over, the economically recoverable resource for the UK is estimated at 25% of current demand; a lot less, but a very substantial amount nonetheless....

  13. Reconstruction of the projected electrostatic potential in high-resolution transmission electron microscopy including phenomenological absorption

    Energy Technology Data Exchange (ETDEWEB)

    Lentzen, M., E-mail: m.lentzen@fz-juelich.de [Institute of Solid State Research and Ernst Ruska Centre for Microscopy, Research Centre Juelich, 52425 Juelich (Germany)

    2010-04-15

    The projected electrostatic potential is reconstructed from a high-resolution exit wave function through a maximum-likelihood refinement algorithm. The theory of an already existing algorithm is extended to include the effects of phenomenological absorption. Various tests with a simulated exit wave function of YBa{sub 2}Cu{sub 3}O{sub 7} in [1 0 0] orientation used as a source show that the reconstruction is successful, regardless of the strongly differing scattering power of atomic columns, even for the case of strong dynamical diffraction. Object thickness, the amount of absorption, and a residual defocus aberration of the wave function-parameters often unknown or difficult to measure in experiments-can be determined accurately with the aid of the refinement algorithm in a self-consistent way. For the next generation of instruments, with information limits of 0.05 nm and better, reconstruction accuracies of better than 2% can be expected, which is sufficient to measure and display the structural and chemical information with the aid of an accurate projected potential map.

  14. Reconstruction method with data from a multiple-site continuous-wave source for three-dimensional optical tomography.

    Science.gov (United States)

    Su, Jianzhong; Shan, Hua; Liu, Hanli; Klibanov, Michael V

    2006-10-01

    A method is presented for reconstruction of the optical absorption coefficient from transmission near-infrared data with a cw source. As it is distinct from other available schemes such as optimization or Newton's iterative method, this method resolves the inverse problem by solving a boundary value problem for a Volterra-type integral-differential equation. It is demonstrated in numerical studies that this technique has a better than average stability with respect to the discrepancy between the initial guess and the actual unknown absorption coefficient. The method is particularly useful for reconstruction from a large data set obtained from a CCD camera. Several numerical reconstruction examples are presented.

  15. Exit and Paradise Creek Fluvial Features, 1950

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset presents a delineation of the maximum extent of fluvial occupation detectable from vegetation patterns at Exit and Paradise Creeks in Kenai Fjords...

  16. Firm Exit, Technological Progress and Trade

    DEFF Research Database (Denmark)

    Schröder, Philipp; Sørensen, Allan

    The dynamics of export market exit and firm closure have found limited attention in the new heterogeneous-firms trade literature. In fact, several of the predictions on firm survival and exit stemming from this new class of models are at odds with the stylized facts. Empirically, higher...... productivity firms survive longer, most firm closures are young firms, higher productivity exporters are more likely to continue to export compared to less productive exporters and market exits as well as firm closures are typically preceded by periods of contracting market shares. The present paper shows...... that the simple inclusion of exogenous economy wide technological progress into the standard Melitz (2003) model generates a tractable dynamic framework that generates endogenous exit decisions of firms in line with the stylized facts. Furthermore, we derive the effects of faster technological progress and trade...

  17. Low-Pressure Burst-Mode Focused Ultrasound Wave Reconstruction and Mapping for Blood-Brain Barrier Opening: A Preclinical Examination

    Science.gov (United States)

    Xia, Jingjing; Tsui, Po-Hsiang; Liu, Hao-Li

    2016-06-01

    Burst-mode focused ultrasound (FUS) exposure has been shown to induce transient blood-brain barrier (BBB) opening for potential CNS drug delivery. FUS-BBB opening requires imaging guidance during the intervention, yet current imaging technology only enables postoperative outcome confirmation. In this study, we propose an approach to visualize short-burst low-pressure focal beam distribution that allows to be applied in FUS-BBB opening intervention on small animals. A backscattered acoustic-wave reconstruction method based on synchronization among focused ultrasound emission, diagnostic ultrasound receiving and passively beamformed processing were developed. We observed that focal beam could be successfully visualized for in vitro FUS exposure with 0.5-2 MHz without involvement of microbubbles. The detectable level of FUS exposure was 0.467 MPa in pressure and 0.05 ms in burst length. The signal intensity (SI) of the reconstructions was linearly correlated with the FUS exposure level both in-vitro (r2 = 0.9878) and in-vivo (r2 = 0.9943), and SI level of the reconstructed focal beam also correlated with the success and level of BBB-opening. The proposed approach provides a feasible way to perform real-time and closed-loop control of FUS-based brain drug delivery.

  18. Exploring the Reasons and Ways to Exit: The Entrepreneur Perspective

    NARCIS (Netherlands)

    Parastuty, Zulaicha; Breitenecker, Robert J.; Schwarz, Erich J.; Harms, Rainer; Bögenhold, Dieter; Bonnet, Jean; Dejardin, Marcus; Garcia Perez de Lema, Domingo

    2016-01-01

    Research on entrepreneurial exit has received growing attention recently, attributing to the importance of exit in the entrepreneurial process. Yet, the complex phenomena of exit render the research scattered in the field. This research is aimed at understanding entrepreneurial exit at the

  19. 10 CFR 431.202 - Definitions concerning illuminated exit signs.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 3 2010-01-01 2010-01-01 false Definitions concerning illuminated exit signs. 431.202... COMMERCIAL AND INDUSTRIAL EQUIPMENT Illuminated Exit Signs § 431.202 Definitions concerning illuminated exit signs. Basic model means, with respect to illuminated exit signs, all units of a given type of...

  20. Tritium in Exit Signs | RadTown USA | US EPA

    Science.gov (United States)

    2017-08-07

    Many exit signs contain tritium to light the sign without batteries or electricity. Using tritium in exit signs allows the sign to remain lit if the power goes out. Tritium is most dangerous when it is inhaled or swallowed. Never tamper with a tritium exit sign. If a tritium exit sign is broken, leave the area immediately and notify the building maintenance staff.

  1. The Political Economy of Early Exit

    DEFF Research Database (Denmark)

    Schmitt, Carina; Starke, Peter

    2016-01-01

    Large-scale exit from the labour market began in the 1970s in many OECD countries. The literature indicates that individual early retirement decisions are facilitated by generous and accessible ‘pathways’ into retirement in the public pension system, unemployment insurance or disability benefits....... It is unclear, however, why early exit became so much more prevalent in some countries than in others and why such differences remain, despite a recent shift back towards higher employment rates and ‘active ageing’. We test a logic of sectoral cost-shifting politics involving cross-class alliances...

  2. Scholars Probe Diverse Effects of Exit Exams

    Science.gov (United States)

    Viadero, Debra

    2009-01-01

    The author reports on a study released in April 2009 that suggests that California's high school exit exams are affecting some student demographic groups more than others. The California study, which was released by the Institute for Research on Education Policy and Practice at Stanford University, is the latest in a small spate of studies…

  3. 14 CFR 27.807 - Emergency exits.

    Science.gov (United States)

    2010-01-01

    ... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT AIRWORTHINESS... that may result from a crash; (2) Doors intended for normal use may also serve as emergency exits... shown by test, demonstration, or analysis to; (i) Be above the waterline; and (ii) Open without...

  4. Learner Washback Variability in Standardized Exit Tests

    Science.gov (United States)

    Pan, Yi-Ching

    2014-01-01

    In much of the world, the issue of accountability and measurement of educational outcomes is highly controversial. Exit testing is part of the movement to ascertain what students have learned and hold institutions and teachers to account. However, compared to the large number of teacher washback studies, learner washback research is lacking…

  5. Chaperone binding at the ribosomal exit tunnel

    DEFF Research Database (Denmark)

    Kristensen, Ole; Gajhede, Michael

    2003-01-01

    The exit tunnel region of the ribosome is well established as a focal point for interaction between the components that guide the fate of nascent polypeptides. One of these, the chaperone trigger factor (TF), associates with the 50S ribosomal subunit through its N-terminal domain. Targeting of TF...

  6. Epigenetics as a First Exit Problem

    Science.gov (United States)

    Aurell, E.; Sneppen, K.

    2002-01-01

    We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the λ prophage. The formalism defines a quantitative measure of robustness of inherited states.

  7. Taking the right to exit seriously

    NARCIS (Netherlands)

    Spiecker, B.; de Ruyter, D.J.; Steutel, J.W.

    2006-01-01

    Both diversity and autonomy liberals agree that adults have the right to exit from voluntary associations. As children do not have this right, the paradoxical character of the upbringing of children in fundamentalist and ultra-orthodox communities is evident. Diversity liberals like Galston and

  8. Effect of exit locations on ants escaping a two-exit room stressed with repellent

    Science.gov (United States)

    Wang, Shujie; Cao, Shuchao; Wang, Qiao; Lian, Liping; Song, Weiguo

    2016-09-01

    In order to investigate the effect of the distance between two exits on ant evacuation efficiency and the behavior of ants escaping from a two-exit room, we conducted ant egress experiments using Camponotus japonicus in multiple situations. We found that the ants demonstrated the phenomenon of ;symmetry breaking; in this stress situation. It was also shown that different locations for the exits obviously affected the ants' egress efficiency by measuring the time intervals between individual egress and flow rate in eight repeated experiments, each of which contained five different distance between the two exits. In addition, it is demonstrated that there are differences between the predictions of Social Force Model of pedestrians and the behaviors of ants in stress conditions through comparing some important behavioral features, including position, trajectory, velocity, and density map.

  9. A novel neural network based image reconstruction model with scale and rotation invariance for target identification and classification for Active millimetre wave imaging

    Science.gov (United States)

    Agarwal, Smriti; Bisht, Amit Singh; Singh, Dharmendra; Pathak, Nagendra Prasad

    2014-12-01

    Millimetre wave imaging (MMW) is gaining tremendous interest among researchers, which has potential applications for security check, standoff personal screening, automotive collision-avoidance, and lot more. Current state-of-art imaging techniques viz. microwave and X-ray imaging suffers from lower resolution and harmful ionizing radiation, respectively. In contrast, MMW imaging operates at lower power and is non-ionizing, hence, medically safe. Despite these favourable attributes, MMW imaging encounters various challenges as; still it is very less explored area and lacks suitable imaging methodology for extracting complete target information. Keeping in view of these challenges, a MMW active imaging radar system at 60 GHz was designed for standoff imaging application. A C-scan (horizontal and vertical scanning) methodology was developed that provides cross-range resolution of 8.59 mm. The paper further details a suitable target identification and classification methodology. For identification of regular shape targets: mean-standard deviation based segmentation technique was formulated and further validated using a different target shape. For classification: probability density function based target material discrimination methodology was proposed and further validated on different dataset. Lastly, a novel artificial neural network based scale and rotation invariant, image reconstruction methodology has been proposed to counter the distortions in the image caused due to noise, rotation or scale variations. The designed neural network once trained with sample images, automatically takes care of these deformations and successfully reconstructs the corrected image for the test targets. Techniques developed in this paper are tested and validated using four different regular shapes viz. rectangle, square, triangle and circle.

  10. 46 CFR 78.47-40 - Exit signs.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 3 2010-10-01 2010-10-01 false Exit signs. 78.47-40 Section 78.47-40 Shipping COAST... Emergency Equipment, Etc. § 78.47-40 Exit signs. (a) Illuminated exit signs are required and must be... sign in red letters “EMERGENCY EXIT” directing attention to such escape. Cross Reference: See...

  11. EOS Terra Terra Constellation Exit/Future Maneuver Plans Update

    Science.gov (United States)

    Mantziaras, Dimitrios

    2016-01-01

    This EOS Terra Constellation Exit/Future Maneuver Plans Update presentation will discuss brief history of Terra EOM work; lifetime fuel estimates; baseline vs. proposed plan origin; resultant exit orbit; baseline vs. proposed exit plan; long term orbit altitude; revised lifetime proposal and fallback options.

  12. Profile of State High School Exit Exam Policies. New Mexico

    Science.gov (United States)

    Center on Education Policy, 2011

    2011-01-01

    This individual profile provides information on New Mexico's high school exit exam standards and policies. Some of the categories presented include: (1) State exit exam policy; (2) Type of Test; (3) Purpose; (4) Major changes in exit exam policy since the 2009-10 school year for financial reasons; (5) Subjects tested on exam; (6) Grade exam first…

  13. Information content in frequency-dependent, multi-offset GPR data for layered media reconstruction using full-wave inversion

    Science.gov (United States)

    De Coster, Albéric; Phuong Tran, Anh; Lambot, Sébastien

    2014-05-01

    Water lost through leaks can represent high percentages of the total production in water supply systems and constitutes an important issue. Leak detection can be tackled with various techniques such as the ground-penetrating radar (GPR). Based on this technology, various procedures have been elaborated to characterize a leak and its evolution. In this study, we focus on a new full-wave radar modelling approach for near-field conditions, which takes into account the antenna effects as well as the interactions between the antenna(s) and the medium through frequency-dependent global transmission and reflection coefficients. This approach is applied to layered media for which 3-D Green's functions can be calculated. The model allows for a quantitative estimation of the properties of multilayered media by using full-wave inversion. This method, however, proves to be limited to provide users with an on-demand assessment as it is generally computationally demanding and time consuming, depending on the medium configuration as well as the number of unknown parameters to retrieve. In that respect, we propose two leads in order to enhance the parameter retrieval step. The first one consists in analyzing the impact of the reduction of the number of frequencies on the information content. For both numerical and laboratory experiments, this operation has been achieved by investigating the response surface topography of objective functions arising from the comparison between measured and modelled data. The second one involves the numerical implementation of multistatic antenna configurations with constant and variable offsets in the model. These two kinds of analyses are then combined in numerical experiments to observe the conjugated effect of the number of frequencies and the offset configuration. To perform the numerical analyses, synthetic Green's functions were simulated for different multilayered medium configurations. The results show that an antenna offset increase leads

  14. Near-field investigation of the explosive dispersal of radioactive material based on a reconstructed spherical blast-wave flow.

    Science.gov (United States)

    Hummel, David; Ivan, Lucian

    2017-06-01

    A "dirty bomb" is a type of radiological dispersal device (RDD) that has been the subject of significant safety and security concerns given the disruption that would result from a postulated terrorist attack. Assessing the risks of radioactive dose in a hypothetical scenario requires models that can accurately predict dispersion in a realistic environment. Modelling a RDD is complicated by the fact that the most important phenomena occur over vastly disparate spatial and temporal length scales. Particulate dispersion in the air is generally considered on scales of hundreds to thousands of meters, and over periods of minutes and hours. Dispersion models are extremely sensitive, however, to the particle size and source characterization, which are determined in distances measured in micrometers to meters, over milliseconds or less. This study examines the extent to which the explosive blast determines the transport of contaminant particles relative to the atmospheric wind over distances relevant to "near-field" dispersion problems (i.e., hundreds of meters), which are relevant to urban environments. Our results indicate that whether or not the effect of the blast should be included in a near-field dispersion model is largely dependent on the size of the contaminant particle. Relatively large particles (i.e., >40 μm in diameter), which are most likely to be produced by a RDD, penetrate the leading shock front, thereby avoiding the reverse blast wind. Consequently, they travel much farther than suspended aerosols (dispersion problems in urban environments, the transport of contaminants from the blast wave may be integral to accurately predicting their dispersion. Crown Copyright © 2017. Published by Elsevier Ltd. All rights reserved.

  15. Entrepreneurial spawning: Experience, education, and exit

    OpenAIRE

    Cumming, Douglas; Walz, Uwe; Werth, Jochen Christian

    2016-01-01

    We investigate the career dynamics of high-tech entrepreneurs by analyzing the exit choice of entrepreneurs: to act as a business angel, to found another firm, or to become dependently employed. Our detailed data from CrunchBase indicate that founders are more likely to stick with entrepreneurship as a serial entrepreneur or as an angel investor in cases where the founder had prior experience either in founding other startups or working for a startup, or had a 'jack-of-all-trades' education.

  16. BST2/Tetherin Inhibition of Alphavirus Exit

    Directory of Open Access Journals (Sweden)

    Yaw Shin Ooi

    2015-04-01

    Full Text Available Alphaviruses such as chikungunya virus (CHIKV and Semliki Forest virus (SFV are small enveloped RNA viruses that bud from the plasma membrane. Tetherin/BST2 is an interferon-induced host membrane protein that inhibits the release of many enveloped viruses via direct tethering of budded particles to the cell surface. Alphaviruses have highly organized structures and exclude host membrane proteins from the site of budding, suggesting that their release might be insensitive to tetherin inhibition. Here, we demonstrated that exogenously-expressed tetherin efficiently inhibited the release of SFV and CHIKV particles from host cells without affecting virus entry and infection. Alphavirus release was also inhibited by the endogenous levels of tetherin in HeLa cells. While rubella virus (RuV and dengue virus (DENV have structural similarities to alphaviruses, tetherin inhibited the release of RuV but not DENV. We found that two recently identified tetherin isoforms differing in length at the N-terminus exhibited distinct capabilities in restricting alphavirus release. SFV exit was efficiently inhibited by the long isoform but not the short isoform of tetherin, while both isoforms inhibited vesicular stomatitis virus exit. Thus, in spite of the organized structure of the virus particle, tetherin specifically blocks alphavirus release and shows an interesting isoform requirement.

  17. Spatial signals link exit from mitosis to spindle position.

    Science.gov (United States)

    Falk, Jill Elaine; Tsuchiya, Dai; Verdaasdonk, Jolien; Lacefield, Soni; Bloom, Kerry; Amon, Angelika

    2016-05-11

    In budding yeast, if the spindle becomes mispositioned, cells prevent exit from mitosis by inhibiting the mitotic exit network (MEN). The MEN is a signaling cascade that localizes to spindle pole bodies (SPBs) and activates the phosphatase Cdc14. There are two competing models that explain MEN regulation by spindle position. In the 'zone model', exit from mitosis occurs when a MEN-bearing SPB enters the bud. The 'cMT-bud neck model' posits that cytoplasmic microtubule (cMT)-bud neck interactions prevent MEN activity. Here we find that 1) eliminating cMT- bud neck interactions does not trigger exit from mitosis and 2) loss of these interactions does not precede Cdc14 activation. Furthermore, using binucleate cells, we show that exit from mitosis occurs when one SPB enters the bud despite the presence of a mispositioned spindle. We conclude that exit from mitosis is triggered by a correctly positioned spindle rather than inhibited by improper spindle position.

  18. Fatal exit the automotive black box debate

    CERN Document Server

    Kowalick, Tom

    2005-01-01

    "Fatal Exit: The Automotive Black Box Debate cuts through thirty years of political wrangling and institutional biases to provide an argument for the Motor Vehicle Event Data Recorder (MVEDR). This automotive equivalent of an airplane's flight recorder or black box is intended to solve the mysteries of car crashes and improve the safety of our roads. The reader is taken inside the automotive industry and the government highway safety establishment to foster an understanding of the politics and the positions on all sides of this safety debate. The author takes an unbiased approach, chronologically presenting each argument and uncovering the agendas and mandates of each of the stakeholders." "This publication is essential reading for all consumers who need to have their voices heard on this critical issue, as well as for attorneys, public safety advocates, public policy administrators, engineers, automotive professionals, journalists, and insurance executives."--Jacket.

  19. Going, Going, Gone. Innovation and Exit in Manufacturing Firms

    OpenAIRE

    Cefis, Elena; Marsili, Orietta

    2007-01-01

    textabstractThis paper examines the effect of innovation on the risk of exit of a firm, distinguishing between different modes of exits. Innovation represents a resource and a capability that helps a firm to build competitive advantage and remain in the market. At the same time, the resources and capabilities of innovative firms make them an attractive target for the acquisition process of other firms, thereby increasing the likelihood of the exiting the market. We explore these effects empir...

  20. Bank exit legislation in US, EU and Japanese financial centres

    OpenAIRE

    Peik Granlund

    2002-01-01

    This paper analyses bank exit (ie reorganisation and liquidation) legislation in selected financial centres: New York, London, Frankfurt, Helsinki and Tokyo. The focus is on bank exit legislation applicable to commercial banks. The legislation is analysed from the perspective of bank stakeholders, ie bank creditors, depositors and bank shareholders. The analysis is restricted to those legislative provisions that provide security and rights for stakeholders in case of bank exit. In addition to...

  1. On Formal vs. Realistic Right of Exit and Voice

    OpenAIRE

    Hyyrynen (Isopoussu), Milla-Maria

    2011-01-01

    In my Master's thesis I discuss a relatively new topic in the discussion on multiculturalism in political philosophy, the right of exit from a religious or a cultural group. Liberal theorists agree on the fact that everyone should be free to leave their group, to have a right to exit. However, they disagree on the content of the right. I present two schools on the topic: the formal right of exit strategy by Chandran Kukathas and the realistic right of exit strategy by Susan Moller Okin. ...

  2. Modified Static Floor Field and Exit Choice for Pedestrian Evacuation

    Science.gov (United States)

    Xu, Yan; Huang, Hai-Jun; Yong, Gui

    2012-08-01

    An improved floor field model is proposed to simulate the pedestrian evacuation behavior in a room with multiple exits by modifying the static floor field. The modified static floor field is determined additionally by two cognitive coefficients of exit width and congestion degree around the exits. The logit-based discrete choice principle is used to govern the initial exit selection strategy based on the modified static floor field in such a scenario that pedestrians are distributed in the room's specified zone. Simulation results show that the proposed model can better perform the evacuation process. Sensitivity analyses of the model parameters are also presented.

  3. The Relevance of Business Exit for Future Entrepreneurial Activity

    OpenAIRE

    Judit Albiol-Sánchez

    2016-01-01

    The Relevance of Business Exit for Future Entrepreneurial Activity Territories can capitalize on knowledge resulting from business exit by designing policies that distinguish first-time entrepreneurs who need specific support and information from individuals with an entrepreneurial background whose experience might help enhance the quality of future entrepreneurial activity.

  4. 14 CFR 29.809 - Emergency exit arrangement.

    Science.gov (United States)

    2010-01-01

    ... 29.809 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION AIRCRAFT... emergency exit in a minor crash landing as a result of fuselage deformation under the ultimate inertial... be qualified by five consecutive deployment and inflation tests conducted (per exit) without failure...

  5. Going, Going, Gone. Innovation and Exit in Manufacturing Firms

    NARCIS (Netherlands)

    E. Cefis (Elena); O. Marsili (Orietta)

    2007-01-01

    textabstractThis paper examines the effect of innovation on the risk of exit of a firm, distinguishing between different modes of exits. Innovation represents a resource and a capability that helps a firm to build competitive advantage and remain in the market. At the same time, the resources and

  6. 14 CFR 29.811 - Emergency exit marking.

    Science.gov (United States)

    2010-01-01

    ... each floor emergency exit, except that one sign may serve two exits if both exists can be seen readily... each locating sign must have white letters 1 inch high on a red background 2 inches high, be self or... colors may be reversed if this will increase the emergency illumination of the passenger compartment. (e...

  7. 14 CFR 23.813 - Emergency exit access.

    Science.gov (United States)

    2010-01-01

    ... AIRWORTHINESS STANDARDS: NORMAL, UTILITY, ACROBATIC, AND COMMUTER CATEGORY AIRPLANES Design and Construction Personnel and Cargo Accommodations § 23.813 Emergency exit access. (a) For commuter category airplanes, access to window-type emergency exits may not be obstructed by seats or seat backs. (b) In addition, when...

  8. An unusual exit wound as a result of a shotgun suicide to the head.

    Science.gov (United States)

    Kunz, S N

    2017-06-01

    The location of a gunshot entrance wound as well as the wound path trajectory are the main findings that help to determine the position from which a weapon was fired and thus distinguish firearm suicides from homicides and accidents. We present a case of a 28-year old man, who was found dead in his car. Because of an unusual position of the firearm, which was clamped into the steering wheel, and an unclear entrance/exit wound, an autopsy was performed. The deceased showed typical signs of a contact shotgun wound to the head with an entrance wound in the right temporal region and an exit wound in the midface. With the help of gunpowder attachments and a muzzle imprint at the entrance site, a wound channel from the right lower posterior part of the temporal region to the left anterior part of the mid-facial region could be reconstructed. The stellate wound in the midface was assessed as an atypical exit wound. The cause of death was a contact shotgun shot to the right temple with a consequent central regulatory failure due to extensive brain injury. The manner of death was concluded to be a suicide. Copyright © 2017 Elsevier B.V. All rights reserved.

  9. Is the publication of exit poll results morally permissible?

    DEFF Research Database (Denmark)

    Sønderholm, Jørn

    2016-01-01

    This article is about exit polls. It addresses the question of whether or not it is morally permissible to publish exit poll results. The conclusion of the article is that an affirmative answer should be given to this question. In section 2, the master argument in favor of the moral permissibility...... of the publication of exit poll results is introduced. This is a strong argument. It is, however, argued that it might be the case that the conclusion of this argument should be rejected if there are other, and weightier, arguments against the idea that the publication of exit poll results is morally permissible....... In section 3, the strongest arguments against the moral permissibility of the publication of exit poll results are outlined and discussed. The conclusion of this section is that all these arguments fail in their intended purpose. The conclusion of the article is therefore justified....

  10. Differences in Student Achievement between Early-Exit and Late-Exit Bilingual Programs: A Multiyear, Statewide Investigation

    Science.gov (United States)

    Martinez, Rosa Maria

    2014-01-01

    Purpose The purpose of this study was to examine the difference between two bilingual program types: traditional early-exit and late-exit bilingual programs and academic achievement using archival data from the Texas Education Agency Public Education Information Management System. An examination of academic achievement rates across a 3-year period…

  11. A Case Report of Rash at Peritoneal Dialysis Exit Site

    Directory of Open Access Journals (Sweden)

    Elvira O. Gosmanova MD, FASN

    2015-11-01

    Full Text Available The International Society for Peritoneal Dialysis recommends the regular application of topical antibiotic-containing preparations in addition to a routine exit site care to reduce the risk of exit site infection (ESI. Among these prophylactic antimicrobial preparations, topical gentamicin is one of the widely used and effective antibiotics for prevention of ESI and peritonitis in peritoneal dialysis (PD patients. Overall, topical gentamicin is well tolerated; however, its use can be associated with the development of allergic contact dermatitis (ACD. We describe a first reported case of PD catheter exit site contact ACD due to topical gentamicin mimicking ESI. The patient in this report developed worsening violaceous in color and pruritic rash surrounding the PD catheter exit site that appeared 3 weeks after the initiation of gentamicin cream. The association between development of rash and initiation of topical gentamicin led to a suspicion of local reaction to gentamicin rather than ESI. Skin biopsy confirmed ACD. Discontinuation of the provoking agent and subsequent treatment with topical hydrocortisone application led to a resolution of the exit site rash. Any rash at a PD catheter exit site should be considered infectious until proven otherwise. However, it is important to be aware of noninfectious etiologies of exit site rashes as the treatment of these 2 conditions differs.

  12. Mean exit times for free inertial stochastic processes

    Energy Technology Data Exchange (ETDEWEB)

    Porra, J.M. (Department of Chemistry, University of California, San Diego, La Jolla, California 92093-0340 (United States)); Masoliver, J. (Departament de Fisica Fonamental, Universitat de Barcelona, Diagonal 647, 08028 Barcelona (Spain)); Lindenberg, K. (Department of Chemistry and Institute for Nonlinear Science, University of California, San Diego, La Jolla, California 92093-0340 (United States))

    1994-09-01

    We study the mean exit time of a free inertial random process from a region in space. The acceleration alternatively takes the values +[ital a] and [minus][ital a] for random periods of time governed by a common distribution [psi]([ital t]). The mean exit time satisfies an integral equation that reduces to a partial differential equation if the random acceleration is Markovian. Some qualitative features of the behavior of the system are discussed and checked by simulations. Among these features, the most striking is the discontinuity of the mean exit time as a function of the initial conditions.

  13. Safety and operational performance evaluation of four types of exit ramps on Florida's freeways (final report).

    Science.gov (United States)

    2010-12-01

    This project mainly focuses on exit ramp performance analysis of safety and operations. In addition, issues of advance guide sign for exit ramp are also mentioned. : Safety analysis evaluates safety performances of different exit ramps used in Florid...

  14. Critical Doping for the Onset of Fermi-Surface Reconstruction by Charge-Density-Wave Order in the Cuprate Superconductor La_{2-x}Sr_{x}CuO_{4}

    Directory of Open Access Journals (Sweden)

    S. Badoux

    2016-04-01

    Full Text Available The Seebeck coefficient S of the cuprate superconductor La_{2-x}Sr_{x}CuO_{4} (LSCO was measured in magnetic fields large enough to access the normal state at low temperatures, for a range of Sr concentrations from x=0.07 to x=0.15. For x=0.11, 0.12, 0.125, and 0.13, S/T decreases upon cooling to become negative at low temperatures. The same behavior is observed in the Hall coefficient R_{H}(T. In analogy with other hole-doped cuprates at similar hole concentrations p, the negative S and R_{H} show that the Fermi surface of LSCO undergoes a reconstruction caused by the onset of charge-density-wave modulations. Such modulations have indeed been detected in LSCO by x-ray diffraction in precisely the same doping range. Our data show that in LSCO this Fermi-surface reconstruction is confined to 0.085wave order ends at a critical doping p_{CDW}=0.15±0.005, well below the pseudogap critical doping p^{⋆}≃0.19.

  15. Exit and Paradise Creek Drainage Area Boundaries, Alaska, 2012

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This dataset contains drainage area boundaries for Exit Creek and Paradise Creek in Kenai Fjords National Park, Alaska. A drainage area boundary identifies the land...

  16. Behavior of Ants Escaping from a Single-Exit Room.

    Science.gov (United States)

    Wang, Shujie; Lv, Wei; Song, Weiguo

    2015-01-01

    To study the rules of ant behavior and group-formation phenomena, we examined the behaviors of Camponotus japonicus, a species of large ant, in a range of situations. For these experiments, ants were placed inside a rectangular chamber with a single exit that also contained a filter paper soaked in citronella oil, a powerful repellent. The ants formed several groups as they moved toward the exit to escape. We measured the time intervals between individual escapes in six versions of the experiment, each containing an exit of a different width, to quantify the movement of the groups. As the ants exited the chamber, the time intervals between individual escapes changed and the frequency distribution of the time intervals exhibited exponential decay. We also investigated the relationship between the number of ants in a group and the group flow rate.

  17. Customer Protest: Exit, Voice or Negative Word of Mouth

    National Research Council Canada - National Science Library

    Solvang, B. K

    2008-01-01

    ... negative word of mouth activity they will experience and they will reduce the exit propensity and lead the customers to the complain organisation. They should also ensure that their customers feel they get equal treatment by the staff.

  18. Entry and Exit Dynamics of Nascent Business Owners

    DEFF Research Database (Denmark)

    Rocha, Vera; Carneiro, Anabela; Varum, Celeste

    2015-01-01

    This paper reports a comprehensive study on the dynamics of nascent business owners using a unique longitudinal matched employer–employee dataset. We follow over 157,000 individuals who leave paid employment and become business owners during the period 1992–2007. The contributions of this paper...... are twofold. First, we analyze both entry and exit, identifying and characterizing different profiles of individuals leaving paid employment to become business owners, and distinguishing exits by dissolution from exits by ownership transfer. Second, we provide new evidence on how particular experiences...... in the labor market and entry modes shape the post-entry dynamics of nascent business owners. By differentiating between different entry and exit routes, this paper provides new evidence on different human capital patterns among nascent business owners and on key determinants of entrepreneurial survival. Our...

  19. A Simple Model for Extrapolating Dose from Penetration Exits

    Energy Technology Data Exchange (ETDEWEB)

    Stevens, A. J. [Brookhaven National Lab. (BNL), Upton, NY (United States)

    1997-06-10

    Penetrations of various types exist in shielding used for radiation protection. In some cases the actual exit of the penetration may be inaccessible, but a person may have access to some region off to the side of the penetration. Since the exit is generally "hot", a general concern is how much dose from the exit can "shine" on a region where access is permitted. This note describes a very simple model for estimating such shine. Two important underlying assumptions, which are not discussed further, are that (1) some means of estimating the dose at the exit of the penetration exists, and (2) that the source of the radiation at the entrance to the penetration is a reasonably diffuse radiation field dominated by low energy neutrons. An example to which the model described below would not apply would be a straight penetration pointed directly at a target of high energy proton interaction.

  20. Behavior of Ants Escaping from a Single-Exit Room.

    Directory of Open Access Journals (Sweden)

    Shujie Wang

    Full Text Available To study the rules of ant behavior and group-formation phenomena, we examined the behaviors of Camponotus japonicus, a species of large ant, in a range of situations. For these experiments, ants were placed inside a rectangular chamber with a single exit that also contained a filter paper soaked in citronella oil, a powerful repellent. The ants formed several groups as they moved toward the exit to escape. We measured the time intervals between individual escapes in six versions of the experiment, each containing an exit of a different width, to quantify the movement of the groups. As the ants exited the chamber, the time intervals between individual escapes changed and the frequency distribution of the time intervals exhibited exponential decay. We also investigated the relationship between the number of ants in a group and the group flow rate.

  1. [Exit Strategy - Issues Summary : Rocky Mountain Arsenal : January 2005

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is the Exit Strategy spreadsheet developed in a joint meeting between the Rocky Mountain Arsenal Council and the Rocky Mountain Arsenal Committee...

  2. Exit, punishment and rewards in commons dilemmas: an experimental study.

    Directory of Open Access Journals (Sweden)

    Giangiacomo Bravo

    Full Text Available Commons dilemmas are interaction situations where a common good is provided or exploited by a group of individuals so that optimal collective outcomes clash with private interests. Although in these situations, social norms and institutions exist that might help individuals to cooperate, little is known about the interaction effects between positive and negative incentives and exit options by individuals. We performed a modified public good game experiment to examine the effect of exit, rewards and punishment, as well as the interplay between exit and rewards and punishment. We found that punishment had a stronger effect than rewards on cooperation if considered by itself, whereas rewards had a stronger effect when combined with voluntary participation. This can be explained in terms of the 'framing effect', i.e., as the combination of exit and rewards might induce people to attach higher expected payoffs to cooperative strategies and expect better behaviour from others.

  3. Tunneling time, exit time and exit momentum in strong field tunnel ionization

    Energy Technology Data Exchange (ETDEWEB)

    Teeny, Nicolas

    2016-10-18

    Tunnel ionization belongs to the fundamental processes of atomic physics. It is still an open question when does the electron tunnel ionize and how long is the duration of tunneling. In this work we solve the time-dependent Schroedinger equation in one and two dimensions and use ab initio quantum calculations in order to answer these questions. Additionally, we determine the exit momentum of the tunnel ionized electron from first principles. We find out results that are different from the assumptions of the commonly employed two-step model, which assumes that the electron ionizes at the instant of electric field maximum with a zero momentum. After determining the quantum final momentum distribution of tunnel ionized electrons we show that the two-step model fails to predict the correct final momentum. Accordingly we suggest how to correct the two-step model. Furthermore, we determine the instant at which tunnel ionization starts, which turns out to be different from the instant usually assumed. From determining the instant at which it is most probable for the electron to enter the tunneling barrier and the instant at which it exits we determine the most probable time spent under the barrier. Moreover, we apply a quantum clock approach in order to determine the duration of tunnel ionization. From the quantum clock we determine an average tunneling time which is different in magnitude and origin with respect to the most probable tunneling time. By defining a probability distribution of tunneling times using virtual detectors we relate both methods and explain the apparent discrepancy. The results found have in general an effect on the interpretation of experiments that measure the spectra of tunnel ionized electrons, and specifically on the calibration of the so called attoclock experiments, because models with imprecise assumptions are usually employed in order to interpret experimental results.

  4. Transmission of high frequency sound waves through a slug flow jet

    Science.gov (United States)

    Parthasarathy, S. P.; Vijayaraghavan, A.

    1980-01-01

    An analysis has been performed of sound waves which propagate in a pipe with gas flow. At the pipe exit these waves are partially reflected and the remainder are diffracted. The analysis is carried out by resolving the sound at the exit into its Fourier components and then continuing the solution, which is a combination of elementary plane waves, beyond the exit. These waves are of two types: homogeneous waves which propagate to infinity, and inhomogeneous waves with complex wave numbers which decay. The reflected waves are evaluated from the inhomogeneous waves. At the boundary of the jet, refraction of the elementary plane waves is accounted for and the far field sound is evaluated by the method of stationary phase. Comparisons of the theoretical calculations are made with experimental results and with calculations of other theories.

  5. Effect of ACL reconstruction tunnels on stress in the distal femur.

    Science.gov (United States)

    Smolinski, P; O'Farrell, M; Bell, K; Gilbertson, L; Fu, F H

    2013-04-01

    This study examined the change in femoral stress caused by graft tunnels drilled for anterior cruciate ligament (ACL) reconstruction. Using a computational model, the number, geometry and position of the graft tunnels exits were varied to determine the effect on bone stress. A finite element model of the distal femur was developed from a CT scan of a cadaveric knee. To assess the model, the strain calculated computationally was compared to experimentally measured strains in eleven unpaired human cadaver femurs. Using the computational model, the number, geometry and position of the graft tunnel exits were varied to determine the effect on bone stress based on the stress concentration factor: the ratio of bone stress with tunnels to intact bone stress. The results indicated that the second tunnel in double-bundle ACL reconstruction results in approximately a 20 % increase in the maximum femoral stress as compared to single-bundle reconstruction. The highest stresses occur at the tunnel exits. The position of the tunnel exits effects femoral stress with the stress increasing slightly (AM SCR from 0.7 to 1 and PL SCR from 1.2 to 1.3) when the AM tunnel exit is moved anteriorly and having greater increases as the posterior lateral (PL) tunnel exit is moved laterally (PL SCR from 1.2 to 1.7) or posteriorly (PL SCR from 1.2 to 2). In anatomical ACL reconstruction, the tunnel entrances are dictated by anatomy; however, there can be variations in tunnel exit positions. Consideration should be given when positioning tunnel exits on the effect on stress in the femur. Moving the PL tunnel exit laterally or posteriorly increases in the stress at the PL tunnel exit.

  6. 29 CFR 1910.36 - Design and construction requirements for exit routes.

    Science.gov (United States)

    2010-07-01

    ... construction requirements for exit routes. (a) Basic requirements. Exit routes must meet the following design... permanent part of the workplace. (2) An exit must be separated by fire resistant materials. Construction materials used to separate an exit from other parts of the workplace must have a one-hour fire resistance...

  7. Gas turbine combustor exit piece with hinged connections

    Science.gov (United States)

    Charron, Richard C.; Pankey, William W.

    2016-04-26

    An exit piece (66) with an inlet throat (67) that conducts a combustion gas flow (36A) in a path (82) from a combustor (63) to an annular chamber (68) that feeds the first blade section (37) of a gas turbine (26). The exit piece further includes an outlet portion (69) that forms a circumferential segment of the annular chamber. The outlet portion interconnects with adjacent outlet portions by hinges (78A, 78B, 80A, 80B). Each hinge may have a hinge axis (82A, 82B) parallel to a centerline (21) of the turbine. Respective gas flows (36A) are configured by an assembly (60) of the exit pieces to converge on the feed chamber (68) into a uniform helical flow that drives the first blade section with minimal circumferential variations in force.

  8. Evaluating nurse turnover: comparing attitude surveys and exit interviews.

    Science.gov (United States)

    Fottler, M D; Crawford, M A; Quintana, J B; White, J B

    1995-01-01

    High turnover rates among hospital nurses demand rigorous and valid processes of research to determine the reasons motivating such attrition. In most hospitals, the exit interview often provides the only relevant data. The case study reported here examines the relative effectiveness of exit interviews and an employee attitude survey in generating data that are useful in managing nurse retention. The conclusion reached is that the attitude survey generates more data and higher-quality data. Further, the study shows that the use of open-ended questions can provide useful information and probably should be the starting point in developing or supplementing an attitude survey for nurses. Recommendations for improving the usefulness and validity of nurse attitude surveys and exit interviews in managing nurse retention are provided.

  9. Comparison of exit time moment spectra for extrinsic metric balls

    DEFF Research Database (Denmark)

    Hurtado, Ana; Markvorsen, Steen; Palmer, Vicente

    2012-01-01

    We prove explicit upper and lower bounds for the $L^1$-moment spectra for the Brownian motion exit time from extrinsic metric balls of submanifolds $P^m$ in ambient Riemannian spaces $N^n$. We assume that $P$ and $N$ both have controlled radial curvatures (mean curvature and sectional curvature......, respectively) as viewed from a pole in $N$. The bounds for the exit moment spectra are given in terms of the corresponding spectra for geodesic metric balls in suitably warped product model spaces. The bounds are sharp in the sense that equalities are obtained in characteristic cases. As a corollary we also...... obtain new intrinsic comparison results for the exit time spectra for metric balls in the ambient manifolds $N^n$ themselves....

  10. STIMULATION METHODS IMPROVEMENT OF EXIT ROUTE ON RAILWAY TRANSPORT

    Directory of Open Access Journals (Sweden)

    A. I. Verlan

    2014-01-01

    Full Text Available Purpose. The purpose of the article is to assess the costs, which are redistributed in the system «shipper−railroad−consignee» during routing of rail transportation and the development of tariff simulation methods of shippers to the exit routes formation. Methodology. Using economic and mathematical analysis the distribution of costs among the various participants of transportation process during the exit routes formation is investigated in the article. Findings. For implementation of the tariff simulation methods of exit routes and retention of the existing tariff structure it is proposed to provide in the «Tariff catalogue for freight transportation by railway transport of Ukraine» the discount, differentiated from haulage distance. A new method for determining the fees amount for cars supply and removal on approach tracks by train locomotives was also offered. Originality. As a result of the research a new method for determination of the exit rout efficiency that, unlike the existing one, takes into account the various interests of the individual participants in the transportation process was proposed. The dependence of the correction factors to the tariff for freight transportation in their own cars by direct exit routes from distance haulage was obtained. Implementation of these coefficients provides an approximation of railway tariffs to the traffic handling costs. A method for determination the rate of fees for cars supply and removal on approach tracks by train locomotives was offered. Practical value. InUkraine creation of the tariff discounts system for freight transportation by exit routes consistent with international practice and allows bringing the tariff to the real traffic handling cost. This change on the one hand will provide stimulation for private capital investments in infrastructure development and shunting means of approach tracks, on the other – it will fix the shippers to the railroads and stop their outflow

  11. Chlorhexidine for routine PD catheter exit-site care.

    Science.gov (United States)

    Olga, Balafa; Fotis, Zarzoulas; Margarita, Ikonomou; Sofia, Xiromeriti; Konstantinos, Siamopoulos

    2016-09-01

    Although guidelines suggest the routine use of mupirocin or gentamicin at the exit site of PD catheter, our PD unit has been using chlorhexidine gluconate 0.5 % as exit-site care protocol. The aim of this study was to ascertain whether mupirocin application is superior to the traditionally applied chlorhexidine-regarding prevention of exit-site infections and peritonitis in our unit. Stable incident and prevalent patients of our unit were randomized to apply mupirocin or chlorhexidine at exit site. The study started on July 1, 2010, and continued till December 2014. End point was the first episode of exit-site infection or peritonitis. Sixty-two patients (mean age 58.5 ± 14.6 years) were randomized. At the end of follow-up, there were 33 patients on mupirocin treatment and 29 on chlorhexidine. The two groups had no differences in age, sex, PD vintage or PD mode. The only difference between the two groups was the percentage of patients with diabetes, 28 % in chlorhexidine group versus 10 % in mupirocin group. Mean time of follow-up was 28.46 ± 16.37 months. Twenty-four episodes of infections (peritonitis and exit site) were recorded. Time to first infection episode was 32 months in mupirocin group (95 % CI 21.4-42.5) versus 29 months (95 % CI 8.6-49.4) in chlorhexidine group. The Kaplan-Meier survival analysis revealed no difference in the infections between the two protocols (log-rank test, p = 0.477). Mupirocin is not superior in preventing infections comparing with chlorhexidine in this cohort of patients.

  12. {bold Experiments on Critical Phenomena in a Noisy Exit Problem }

    Energy Technology Data Exchange (ETDEWEB)

    Luchinsky, D.G.; McClintock, P.V. [Department of Physics, Lancaster University, Lancaster LA1 4YB (United Kingdom); Maier, R.S.; Stein, D.L. [Department of Mathematics, University of Arizona, Tucson, Arizona 85721 (United States); Mannella, R. [Dipartimento di Fisica, Universita di Pisa, Piazza Torricelli 2, 56100 Pisa (Italy); Maier, R.S.; Stein, D.L. [Department of Physics, University of Arizona, Tucson, Arizona 85721 (United States)

    1997-10-01

    We consider a noise-driven exit from a domain of attraction in a two-dimensional bistable system lacking detailed balance. Through analog and digital stochastic simulations, we find a theoretically predicted bifurcation of the most probable exit path as the parameters of the system are changed, and a corresponding nonanalyticity of the generalized activation energy. We also investigate the extent to which the bifurcation is related to the local breaking of time-reversal invariance. {copyright} {ital 1997} {ital The American Physical Society}

  13. Entrance, exit, and reentrance of one shot with a shotgun

    DEFF Research Database (Denmark)

    Gulmann, C; Hougen, H P

    1999-01-01

    The case being reported is one of a homicidal shotgun fatality with an unusual wound pattern. A 34-year-old man was shot at close range with a 12-gauge shotgun armed with No. 5 birdshot ammunition. The shot entered the left axillary region, exited through the left infraclavicular region, and ther......The case being reported is one of a homicidal shotgun fatality with an unusual wound pattern. A 34-year-old man was shot at close range with a 12-gauge shotgun armed with No. 5 birdshot ammunition. The shot entered the left axillary region, exited through the left infraclavicular region...

  14. Anomalous scattering, transport, and spatial distribution of X-ray fluorescence at the exit of polycapillary structures

    Energy Technology Data Exchange (ETDEWEB)

    Mazuritskiy, M. I., E-mail: mazurmik@gmail.com; Lerer, A. M.; Makhno, P. V. [Southern Federal University (Russian Federation)

    2016-12-15

    The angular distribution of the X-ray intensity at the exit of microchannel plates at grazing incidence of monochromatic radiation on the walls of microcapillaries has been investigated. The angles and energies of the primary radiation quanta at which the synchrotron beam excites X-ray fluorescence propagating inside polycapillary structures have been determined. The angular dependences of the intensity distribution of X-rays transmitted through the microcapillaries have been studied theoretically and experimentally for energies corresponding to the region of anomalous dispersion near the L{sub 2,3} absorption edges of silicon. The propagation of waves in hollow polycapillary waveguides, the excitation of X-ray fluorescence, and the X-ray diffraction at the exit of microchannel plates have been modeled mathematically. The mathematical model takes into account the presence of a transition layer on the microchannel surface.

  15. After exit: Academic achievement patterns of former English language learners.

    Directory of Open Access Journals (Sweden)

    Ester J. de Jong

    2004-09-01

    Full Text Available With few exceptions, accountability systems for programs for English language learners (ELLs have focused on the achievement patterns of ELLs who are still considered “limited English proficient” and program evaluations have been unable to answer the question whether ELLs actually catch up with English proficient peers after attending a bilingual or English as a Second Language (ESL program. Disaggregating data for former ELLs can therefore provide important information for long-term district and program accountability. The study was concerned with the achievement patterns in English language arts, Math, and Science of former ELLs who attended a bilingual and a English as a Second Language (ESL program. It also explored whether length of program participation and grade level exited played a significant role in predicting academic achievement patterns for these exited students. Results indicate that 4th grade students more closely paralleled non- ELL students’ achievement patterns than 8th grade students, particularly for the BE students. While length of program participation is not a significant predictor of former ELLs’ academic success, exit grade does emerge as an important variable to take into consideration in setting exit guidelines.

  16. On satellite umbra/penumbra entry and exit positions

    OpenAIRE

    Neta, Beny; Vellado, David

    1997-01-01

    The problem of computing Earth satellite entry and exit positions through the Earth's umbra and penumbra, for satellites in elliptical orbits, is solved without the use of a quartic equation. A condition for existence of a solution is given. This problem is related to perturbation force resulting from solar radiation pressure.

  17. Exit association-mediated suicide: toxicologic and forensic aspects.

    Science.gov (United States)

    Giroud, C; Augsburger, M; Horisberger, B; Lucchini, P; Rivier, L; Mangin, P

    1999-03-01

    The Swiss German chapter of the Exit Association provides conditional assistance to individuals wishing to end their own lives. The Exit Association advocates death with dignity and fights for the right to freely choose the timing of one's own death. According to the Swiss criminal code (articles 114 and 115), altruistic assistance to suicide is not punishable. Active euthanasia is punished by imprisonment. An individual commits active euthanasia if he or she is driven by honorable motives (e.g., pity) and causes the death of another person wishing to die who seriously and insistently requests such action. Based on our information, the preparation for suicide and its completion relies on a well-defined protocol. First, the candidate's eligibility for Exit Association assistance is verified. The candidate then writes a farewell declaration that explicitly confirms the will to terminate his or her own life. A written report describes the events during the suicide procedure. Depending on the circumstances, the investigative judge requests a forensic autopsy and toxicologic analyses. The results of the forensic investigations conducted in the cases presented here are in agreement with the scenario described in the reports of the Exit Association, namely, suicide by massive ingestion of pentobarbital.

  18. EXIT Chart Analysis of Binary Message-Passing Decoders

    DEFF Research Database (Denmark)

    Lechner, Gottfried; Pedersen, Troels; Kramer, Gerhard

    2007-01-01

    Binary message-passing decoders for LDPC codes are analyzed using EXIT charts. For the analysis, the variable node decoder performs all computations in the L-value domain. For the special case of a hard decision channel, this leads to the well know Gallager B algorithm, while the analysis can...

  19. Stor forskel på kommuners bande-exit

    DEFF Research Database (Denmark)

    Mørck, Line Lerche

    2015-01-01

    DEBAT: Kommunerne har meget forskellige exit-tilbud til bande- og rockermedlemmer. Der er brug for mere indgående forskning, så vi ved, hvad der virker bedst, skriver Line Lerche Mørck, lektor i pædagogisk psykologi....

  20. 14 CFR 25.809 - Emergency exit arrangement.

    Science.gov (United States)

    2010-01-01

    ... AIRWORTHINESS STANDARDS: TRANSPORT CATEGORY AIRPLANES Design and Construction Emergency Provisions § 25.809... sliding window emergency exits in the flight crew area need not be openable from the outside if other... capable of being opened, when there is no fuselage deformation— (1) With the airplane in the normal ground...

  1. Control of the mitotic exit network during meiosis

    Science.gov (United States)

    Attner, Michelle A.; Amon, Angelika

    2012-01-01

    The mitotic exit network (MEN) is an essential GTPase signaling pathway that triggers exit from mitosis in budding yeast. We show here that during meiosis, the MEN is dispensable for exit from meiosis I but contributes to the timely exit from meiosis II. Consistent with a role for the MEN during meiosis II, we find that the signaling pathway is active only during meiosis II. Our analysis further shows that MEN signaling is modulated during meiosis in several key ways. Whereas binding of MEN components to spindle pole bodies (SPBs) is necessary for MEN signaling during mitosis, during meiosis MEN signaling occurs off SPBs and does not require the SPB recruitment factor Nud1. Furthermore, unlike during mitosis, MEN signaling is controlled through the regulated interaction between the MEN kinase Dbf20 and its activating subunit Mob1. Our data lead to the conclusion that a pathway essential for vegetative growth is largely dispensable for the specialized meiotic divisions and provide insights into how cell cycle regulatory pathways are modulated to accommodate different modes of cell division. PMID:22718910

  2. How extremist experiences become valuable knowledge in EXIT programmers

    DEFF Research Database (Denmark)

    Christensen, Tina Wilchen

    2015-01-01

    On the basis of a neo-Vygotskian approach the article analyses how former neo-Nazis, together with other staff at Fryshuset, a youth centre in Stockholm, Sweden, have developed the organisation EXIT, which helps people leave the extremist right. The article describes the processes former neo-Nazis...

  3. Some Features of Aerodynamics of Cyclonic Chamber with Free Exit

    Directory of Open Access Journals (Sweden)

    A. N. Orekhov

    2007-01-01

    Full Text Available The paper cites results of an experimental research in aerodynamics of a cyclonic chamber with a free exit that has a large relative length. Distributions of aerodynamic stream characteristics depending on geometry of working volume of the cyclonic chamber are given in the paper. Calculative dependences are proposed in the paper.

  4. First Experience with OSCE as an Exit Clinical Examination for ...

    African Journals Online (AJOL)

    First Experience with OSCE as an Exit Clinical Examination for General Surgery Residency Program at the Addis Ababa University, School of Medicine. ... with some level of success provided the students and staffs are adequately oriented and convinced of the justifications for an objective assessment in clinical training.

  5. Performance Characteristics of Florida's Early Exit Equivalency Candidates.

    Science.gov (United States)

    Stoker, Howard

    1984-01-01

    The impact of the Early Exit Program (EEP) on Florida schools was studied. Questions asked about those who pass the General Education Development (GED) tests to earn a high school diploma included: (1) whether such students are high achievers who might contribute to a brain drain from the high schools; (2) whether they are low achievers who cannot…

  6. 40 CFR 63.1346 - Standards for new or reconstructed raw material dryers.

    Science.gov (United States)

    2010-07-01

    ... Industry Emission Standards and Operating Limits § 63.1346 Standards for new or reconstructed raw material dryers. (a) New or reconstructed raw material dryers located at facilities that are major sources can not... demonstrate a 98 percent reduction in THC emissions from the exit of the raw materials dryer to discharge to...

  7. "I'm Not Waving, I'm Drowning": An Autoethnographical Exploration of Biographical Disruption and Reconstruction During Recovery From Prescribed Benzodiazepine Use.

    Science.gov (United States)

    Fixsen, Alison M

    2016-03-01

    Benzodiazepines are group of drugs used mainly as sedatives, hypnotics, muscle relaxants, and anti-epileptics. Tapering off benzodiazepines is, for some users, a painful, traumatic, and protracted process. In this article, I use an autoethnographic approach, adopting the metaphor of water, to examine heuristically my experience of iatrogenic illness and recovery. I draw on personal journals and blog entries and former users' narratives to consider the particular form of biographical disruption associated with benzodiazepines and the processes involved in identity reconstruction. I emphasize the role of the online community in providing benzodiazepine users such as myself with a co-cultural community through which to share a voice and make sense of our experiences. I explain how the success stories of former users provided me with the hope that I, the "medical victim," could become the "victor" and in the process construct a new life and fresh identity. © The Author(s) 2015.

  8. Comparability of Semester and Exit Exam Grades: Long-Term Effect of the Implementation of State-Wide Exit Exams

    Science.gov (United States)

    Maag Merki, Katharina; Holmeier, Monika

    2015-01-01

    A goal in many countries is to institute state-wide exams to base student assessment more firmly on norms for all classes. This raises the question as to the extent to which greater standardization of grading practice can be reached by implementing state-wide exit exams. Since there is a lack of longitudinal studies, we analyzed the effect of the…

  9. Spontaneous Localized Persistent Atrial Fibrillation with an Exit Block Mimicking Atrial Tachycardia at the Left Posterior Wall

    Directory of Open Access Journals (Sweden)

    Shoichi Kubota, MD

    2007-01-01

    Full Text Available We describe a 37-year-old man with spontaneous localized atrial fibrillation (AF with an exit block at the posterior wall of the left atrium (LA. The 12-lead ECG exhibited an atrial tachycardia-like pattern, with distinctive P waves and an isoelectric baseline between the P waves. The cycle length of the P waves ranged from 320 to 500 msec. While the fractionated and rapid deflections were recorded from the posterior wall of the LA, the rest of the atria and the coronary sinus exhibited discrete atrial potentials with irregular intervals. Radiofrequency energy applications to the surrounding tissue created complete isolation of the localized AF area, and the AF was terminated. Fibrillatory activation in the posterior wall of the LA can act as a driver as well as an initiator of atrial fibrillation.

  10. Customer Protest: Exit, Voice or Negative Word of Mouth

    Directory of Open Access Journals (Sweden)

    Solvang, B. K.

    2008-01-01

    Full Text Available Of the three forms of protest the propensity of word of mouth (WOM seems to be the most common, and the most exclusive form of protest seems to be exit. The propensity for voice lies in between. The costs linked to voice influence the propensity for WOM. The customers seem to do an evaluation between the three forms of protest, yet the rational picture of the customers should be moderated.Leaders should improve their treatment of the customers making complaints. The more they can treat customer complaints in an orderly and nice way the less informal negative word of mouth activity they will experience and they will reduce the exit propensity and lead the customers to the complain organisation. They should also ensure that their customers feel they get equal treatment by the staff.

  11. Exit Options in Corporate Finance: Liquidity versus Incentives

    OpenAIRE

    Aghion, Philippe; Bolton, Patrick; Tirole, Jean

    2004-01-01

    This paper provides a first study of the optimal design of active monitors' exit options in a problem involving a demand for liquidity and costly monitoring of the issuer. Optimal incentives to monitor the issuer may involve restricting the monitor's right to sell her claims on the firm's cash-flow early. But the monitor will then require a liquidity premium for holding such an illiquid claim. In general, therefore, there will be a trade off between incentives and liquidity. The paper highlig...

  12. TEST IMPACT: ENGLISH CERTIFICATION EXIT REQUIREMENTS IN TAIWAN

    OpenAIRE

    Yi-Ching Pan

    2009-01-01

    Abstract: In light of the importance of understanding the social impacts of test use, this paper synthesizes the opinions and surveys of a variety of stakeholders, including businesses, the government, administrators, educators and students, regarding the English exit requirements, as reported in major local newspapers during the last decade.  It then constructs implications in terms of considerations for those involved in the establishment of the requirements and provides insights and sugge...

  13. Volumetric velocity measurements of vortex rings from inclined exits

    Science.gov (United States)

    Troolin, Daniel R.; Longmire, Ellen K.

    2010-03-01

    Vortex rings were generated by driving pistons within circular cylinders of inner diameter D = 72.8 mm at a constant velocity U 0 over a distance L = D. The Reynolds number, U 0 L/(2ν), was 2500. The flow downstream of circular and inclined exits was examined using volumetric 3-component velocimetry (V3V). The circular exit yields a standard primary vortex ring that propagates downstream at a constant velocity and a lingering trailing ring of opposite sign associated with the stopping of the piston. By contrast, the inclined nozzle yields a much more complicated structure. The data suggest that a tilted primary vortex ring interacts with two trailing rings; one associated with the stopping of the piston, and the other associated with the asymmetry of the cylinder exit. The two trailing ring structures, which initially have circulation of opposite sign, intertwine and are distorted and drawn through the center of the primary ring. This behavior was observed for two inclination angles. Increased inclination was associated with stronger interactions between the primary and trailing vortices as well as earlier breakdown.

  14. Volumetric velocity measurements of vortex rings from inclined exits

    Energy Technology Data Exchange (ETDEWEB)

    Troolin, Daniel R. [TSI Incorporated, Fluid Mechanics Division, St. Paul, MN (United States); Longmire, Ellen K. [University of Minnesota, Department of Aerospace Engineering and Mechanics, Minneapolis, MN (United States)

    2010-03-15

    Vortex rings were generated by driving pistons within circular cylinders of inner diameter D=72.8 mm at a constant velocity U{sub 0} over a distance L=D. The Reynolds number, U{sub 0}L/(2{nu}), was 2500. The flow downstream of circular and inclined exits was examined using volumetric 3-component velocimetry (V3V). The circular exit yields a standard primary vortex ring that propagates downstream at a constant velocity and a lingering trailing ring of opposite sign associated with the stopping of the piston. By contrast, the inclined nozzle yields a much more complicated structure. The data suggest that a tilted primary vortex ring interacts with two trailing rings; one associated with the stopping of the piston, and the other associated with the asymmetry of the cylinder exit. The two trailing ring structures, which initially have circulation of opposite sign, intertwine and are distorted and drawn through the center of the primary ring. This behavior was observed for two inclination angles. Increased inclination was associated with stronger interactions between the primary and trailing vortices as well as earlier breakdown. (orig.)

  15. Discrete element crowd model for pedestrian evacuation through an exit

    Science.gov (United States)

    Peng, Lin; Jian, Ma; Siuming, Lo

    2016-03-01

    A series of accidents caused by crowds within the last decades evoked a lot of scientific interest in modeling the movement of pedestrian crowds. Based on the discrete element method, a granular dynamic model, in which the human body is simplified as a self-driven sphere, is proposed to simulate the characteristics of crowd flow through an exit. In this model, the repulsive force among people is considered to have an anisotropic feature, and the physical contact force due to body deformation is quantified by the Hertz contact model. The movement of the human body is simulated by applying the second Newton’s law. The crowd flow through an exit at different desired velocities is studied and simulation results indicated that crowd flow exhibits three distinct states, i.e., smooth state, transition state and phase separation state. In the simulation, the clogging phenomenon occurs more easily when the desired velocity is high and the exit may as a result be totally blocked at a desired velocity of 1.6 m/s or above, leading to faster-to-frozen effect. Project supported by the National Natural Science Foundation of China (Grant Nos. 71473207, 51178445, and 71103148), the Research Grant Council, Government of Hong Kong, China (Grant No. CityU119011), and the Fundamental Research Funds for the Central Universities, China (Grant Nos. 2682014CX103 and 2682014RC05).

  16. First exit times of harmonically trapped particles: a didactic review

    Science.gov (United States)

    Grebenkov, Denis S.

    2015-01-01

    We revise the classical problem of characterizing first exit times of a harmonically trapped particle whose motion is described by a one- or multidimensional Ornstein-Uhlenbeck process. We start by recalling the main derivation steps of a propagator using Langevin and Fokker-Planck equations. The mean exit time, the moment-generating function and the survival probability are then expressed through confluent hypergeometric functions and thoroughly analyzed. We also present a rapidly converging series representation of confluent hypergeometric functions that is particularly well suited for numerical computation of eigenvalues and eigenfunctions of the governing Fokker-Planck operator. We discuss several applications of first exit times, such as the detection of time intervals during which motor proteins exert a constant force onto a tracer in optical tweezers single-particle tracking experiments; adhesion bond dissociation under mechanical stress; characterization of active periods of trend-following and mean-reverting strategies in algorithmic trading on stock markets; relation to the distribution of first crossing times of a moving boundary by Brownian motion. Some extensions are described, including diffusion under quadratic double-well potential and anomalous diffusion.

  17. Climate Reconstructions

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The NOAA Paleoclimatology Program archives reconstructions of past climatic conditions derived from paleoclimate proxies, in addition to the Program's large holdings...

  18. 29 CFR 1910.37 - Maintenance, safeguards, and operational features for exit routes.

    Science.gov (United States)

    2010-07-01

    ...., sprinkler systems, alarm systems, fire doors, exit lighting) must be in proper working order at all times. (b) Lighting and marking must be adequate and appropriate. (1) Each exit route must be adequately..., or alterations. (1) During new construction, employees must not occupy a workplace until the exit...

  19. 24 CFR 3280.106 - Exit facilities; egress windows and devices.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 5 2010-04-01 2010-04-01 false Exit facilities; egress windows and... § 3280.106 Exit facilities; egress windows and devices. (a) Every room designed expressly for sleeping purposes, unless it has an exit door (see § 3280.105), shall have at least one outside window or approved...

  20. Exit times for a class of random walks: exact distribution results

    DEFF Research Database (Denmark)

    Jacobsen, Martin

    2011-01-01

    the exit possible has a Laplace transform which is a rational function. The expected exit time is also determined and the paper concludes with exact distribution results concerning exits from bounded intervals. The proofs use simple martingale techniques together with some classical expansions...

  1. 36 CFR 13.1312 - Climbing and walking on Exit Glacier.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Climbing and walking on Exit... General Provisions § 13.1312 Climbing and walking on Exit Glacier. Except for areas designated by the Superintendent, climbing or walking on, in, or under Exit Glacier is prohibited within 1/2 mile of the glacial...

  2. Injuries and Unattended Home Exits in Persons with Dementia: A 12-Month Prospective Study

    Science.gov (United States)

    Rowe, Meredeth A.; Ahn, HyoChol; Benito, Andrea Pe; Stone, Heather; Wilson, Amanda

    2009-01-01

    Persons with dementia (PWD) are at particular risk for injuries and unattended home exits. The purposes of this study were to prospectively describe the characteristics and determine the hazard rates of unattended home exits and injuries. Nine times over 12 months, data were collected from 53 PWD’s caregivers about PWD unattended home exits or injuries. Twenty-four percent of PWD had at least one unattended exit; four participants exited multiple times. Males and younger PWD were significantly more likely to exit than females or older individuals. Thirty percent of PWD sustained injuries in 29 separate incidents; all but three injuries were caused by falls, and 38% of injuries resulted in nursing home placement. The hazard rate of untoward events was high, at approximately 1 unattended exit and 1 fall per person-year. For all PWD living in the community, healthcare plans should include specific interventions to prevent these untoward events. PMID:19001350

  3. Compressive passive millimeter wave imager

    Science.gov (United States)

    Gopalsami, Nachappa; Liao, Shaolin; Elmer, Thomas W; Koehl, Eugene R; Heifetz, Alexander; Raptis, Apostolos C

    2015-01-27

    A compressive scanning approach for millimeter wave imaging and sensing. A Hadamard mask is positioned to receive millimeter waves from an object to be imaged. A subset of the full set of Hadamard acquisitions is sampled. The subset is used to reconstruct an image representing the object.

  4. Exit strategy: video-interview to Walter Siti

    Directory of Open Access Journals (Sweden)

    Massimo Fusillo

    2014-12-01

    Full Text Available Sabato 7 Giugno 2014, sulla terrazza dell'Institut français di Palermo, nell'ambito del Sicilia Queer Film Fest 2014 e in collaborazione con la Summer School in "Differenze e identità plurali" dell'Università di Palermo, Massimo Fusillo ha intervistato Walter Siti a proposito dell'ultimo suo romanzo, Exit Strategy (Rizzoli, 2014, e di alcuni momenti chiave della sua poetica. Si ringrazia l'organizzazione, e in particolare Silvia Antosa, per aver curato e concesso la videoregistrazione qui riprodotta.

  5. Destruction and Reallocation of Skills Following Large Company Exit

    DEFF Research Database (Denmark)

    Holm, Jacob Rubæk; Østergaard, Christian Richter; Olesen, Thomas Roslyng

    What happens to redundant skills and workers when a large company closes down in a region? The knowledge embodied in firms is lost when firms exit. However, the skills, competences and knowledge embodied in the displaced employees are suddenly released and can become channels of knowledge transfer...... for other firms that hire them. This process can be very disruptive. For instance, when a large, old and well-renowned company closes down displacing thousands of workers over a short period of time, then it may be a shock to the regional economy and lead to unemployment and skill destruction. The question...

  6. TEST IMPACT: ENGLISH CERTIFICATION EXIT REQUIREMENTS IN TAIWAN

    Directory of Open Access Journals (Sweden)

    Yi-Ching Pan

    2009-01-01

    Full Text Available Abstract: In light of the importance of understanding the social impacts of test use, this paper synthesizes the opinions and surveys of a variety of stakeholders, including businesses, the government, administrators, educators and students, regarding the English exit requirements, as reported in major local newspapers during the last decade.  It then constructs implications in terms of considerations for those involved in the establishment of the requirements and provides insights and suggestions for other stakeholders.  By doing so, it is hoped that this study will be beneficial to those who are active in the fields of English teaching, policy-making and test development.

  7. [Eyebrow reconstruction].

    Science.gov (United States)

    Baraër, F; Darsonval, V; Lejeune, F; Bochot-Hermouet, B; Rousseau, P

    2013-10-01

    The eyebrow is an essential anatomical area, from a social point of view, so its reconstruction, in case of skin defect, must be as meticulous as possible, with the less residual sequela. Capillary density extremely varies from one person to another and the different methods of restoration of this area should absolutely take this into consideration. We are going to review the various techniques of reconstruction, according to the sex and the surface to cover. Copyright © 2013 Elsevier Masson SAS. All rights reserved.

  8. Steam exit flow design for aft cavities of an airfoil

    Science.gov (United States)

    Storey, James Michael; Tesh, Stephen William

    2002-01-01

    Turbine stator vane segments have inner and outer walls with vanes extending therebetween. The inner and outer walls have impingement plates. Steam flowing into the outer wall passes through the impingement plate for impingement cooling of the outer wall surface. The spent impingement steam flows into cavities of the vane having inserts for impingement cooling the walls of the vane. The steam passes into the inner wall and through the impingement plate for impingement cooling of the inner wall surface and for return through return cavities having inserts for impingement cooling of the vane surfaces. A skirt or flange structure is provided for shielding the steam cooling impingement holes adjacent the inner wall aerofoil fillet region of the nozzle from the steam flow exiting the aft nozzle cavities. Moreover, the gap between the flash rib boss and the cavity insert is controlled to minimize the flow of post impingement cooling media therebetween. This substantially confines outflow to that exiting via the return channels, thus furthermore minimizing flow in the vicinity of the aerofoil fillet region that may adversely affect impingement cooling thereof.

  9. A comparison study of water impact and water exit models

    Directory of Open Access Journals (Sweden)

    Korobkin Alexander

    2014-12-01

    Full Text Available In problems of global hydroelastic ship response in severe seas including the whipping problem, we need to know the hydrodynamic forces acting on the ship hull during almost arbitrary ship motions. In terms of ship sections, some of them can enter water but others exit from water. Computations of nonlinear free surface flows, pressure distributions and hydrodynamic forces in parallel with the computations of the ship motions including elastic vibrations of the ship hull are time consuming and are suitable only for research purposes but not for practical calculations. In this paper, it is shown that the slamming forces can be decomposed in two components within three semi-analytical models of water entry. Only heave motion is considered. The first component is proportional to the entry speed squared and the second one to the body acceleration. The coefficients in these two components are functions of the penetration depth only and can be precomputed for given shape of the body. During the exit stage the hydrodynamic force is proportional to the acceleration of the body and independent of the body shape for bodies with small deadrise angles.

  10. Vaginal reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Lesavoy, M.A.

    1985-05-01

    Vaginal reconstruction can be an uncomplicated and straightforward procedure when attention to detail is maintained. The Abbe-McIndoe procedure of lining the neovaginal canal with split-thickness skin grafts has become standard. The use of the inflatable Heyer-Schulte vaginal stent provides comfort to the patient and ease to the surgeon in maintaining approximation of the skin graft. For large vaginal and perineal defects, myocutaneous flaps such as the gracilis island have been extremely useful for correction of radiation-damaged tissue of the perineum or for the reconstruction of large ablative defects. Minimal morbidity and scarring ensue because the donor site can be closed primarily. With all vaginal reconstruction, a compliant patient is a necessity. The patient must wear a vaginal obturator for a minimum of 3 to 6 months postoperatively and is encouraged to use intercourse as an excellent obturator. In general, vaginal reconstruction can be an extremely gratifying procedure for both the functional and emotional well-being of patients.

  11. Conical Refraction of Elastic Waves by Anisotropic Metamaterials and Application for Parallel Translation of Elastic Waves.

    Science.gov (United States)

    Ahn, Young Kwan; Lee, Hyung Jin; Kim, Yoon Young

    2017-08-30

    Conical refraction, which is quite well-known in electromagnetic waves, has not been explored well in elastic waves due to the lack of proper natural elastic media. Here, we propose and design a unique anisotropic elastic metamaterial slab that realizes conical refraction for horizontally incident longitudinal or transverse waves; the single-mode wave is split into two oblique coupled longitudinal-shear waves. As an interesting application, we carried out an experiment of parallel translation of an incident elastic wave system through the anisotropic metamaterial slab. The parallel translation can be useful for ultrasonic non-destructive testing of a system hidden by obstacles. While the parallel translation resembles light refraction through a parallel plate without angle deviation between entry and exit beams, this wave behavior cannot be achieved without the engineered metamaterial because an elastic wave incident upon a dissimilar medium is always split at different refraction angles into two different modes, longitudinal and shear.

  12. Higher effort-reward imbalance and lower job control predict exit from the labour market at the age of 61 years or younger: evidence from the English Longitudinal Study of Ageing.

    Science.gov (United States)

    Hintsa, T; Kouvonen, A; McCann, M; Jokela, M; Elovainio, M; Demakakos, P

    2015-06-01

    We examined whether higher effort-reward imbalance (ERI) and lower job control are associated with exit from the labour market. There were 1263 participants aged 50-74 years from the English Longitudinal Study on Ageing with data on working status and work-related psychosocial factors at baseline (wave 2; 2004-2005), and working status at follow-up (wave 5; 2010-2011). Psychosocial factors at work were assessed using a short validated version of ERI and job control. An allostatic load index was formed using 13 biological parameters. Depressive symptoms were measured using the Center for Epidemiologic Studies Depression Scale. Exit from the labour market was defined as not working in the labour market when 61 years old or younger in 2010-2011. Higher ERI OR=1.62 (95% CI 1.01 to 2.61, p=0.048) predicted exit from the labour market independent of age, sex, education, occupational class, allostatic load and depression. Job control OR=0.60 (95% CI 0.42 to 0.85, p=0.004) was associated with exit from the labour market independent of age, sex, education, occupation and depression. The association of higher effort OR=1.32 (95% CI 1.01 to 1.73, p=0.045) with exit from the labour market was independent of age, sex and depression but attenuated to non-significance when additionally controlling for socioeconomic measures. Reward was not related to exit from the labour market. Stressful work conditions can be a risk for exiting the labour market before the age of 61 years. Neither socioeconomic position nor allostatic load and depressive symptoms seem to explain this association. Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions.

  13. Competitive electricity markets, prices and generator entry and exit

    Science.gov (United States)

    Ethier, Robert George

    The electric power industry in the United States is quickly being deregulated and restructured. In the past, new electric generation capacity was added by regulated utilities to meet forecasted demand levels and maintain reserve margins. With competitive wholesale generation, investment will be the responsibility of independent private investors. Electricity prices will assume the coordinating function which has until recently been the responsibility of regulatory agencies. Competitive prices will provide the entry and exit signals for generators in the future. Competitive electricity markets have a distinctive price formation process, and thus require a specialized price model. A mean-reverting price process with stochastic jumps is proposed as an appropriate long-run price process for annual electricity prices. This price process is used to develop an analytic real options model for private investment decisions. The required recursive infinite series solutions have not been widely used for real option models. Entry thresholds and asset values for competitive wholesale electricity markets, and exit decisions for plants with significant retirement costs (i.e. nuclear power plants), are examined. The proposed model results in significantly lower trigger prices for both entry and exit decisions, and higher asset values, when compared with other standard models. The model is used to show that the incentives for retiring a nuclear plant are very sensitive to the treatment of decommissioning costs (e.g. if plant owners do not face full decommissioning costs, retirement decisions may be economically premature.) An econometric model of short-run price behavior is estimated by the method of maximum likelihood using daily electricity prices from markets in the USA and Australia. The model specifies two mean reverting price processes with stochastic Markov switching between the regimes, which allows discontinuous jumps in electricity prices. Econometric tests show that a two

  14. Breast Reconstruction After Mastectomy

    Science.gov (United States)

    ... Cancers Breast Cancer Screening Research Breast Reconstruction After Mastectomy On This Page What is breast reconstruction? How ... are some new developments in breast reconstruction after mastectomy? What is breast reconstruction? Many women who have ...

  15. Breast reconstruction - implants

    Science.gov (United States)

    Breast implants surgery; Mastectomy - breast reconstruction with implants; Breast cancer - breast reconstruction with implants ... to make reconstruction easier. If you will have breast reconstruction later, your surgeon will remove enough skin ...

  16. Nonlinear reconstruction

    Science.gov (United States)

    Zhu, Hong-Ming; Yu, Yu; Pen, Ue-Li; Chen, Xuelei; Yu, Hao-Ran

    2017-12-01

    We present a direct approach to nonparametrically reconstruct the linear density field from an observed nonlinear map. We solve for the unique displacement potential consistent with the nonlinear density and positive definite coordinate transformation using a multigrid algorithm. We show that we recover the linear initial conditions up to the nonlinear scale (rδrδL>0.5 for k ≲1 h /Mpc ) with minimal computational cost. This reconstruction approach generalizes the linear displacement theory to fully nonlinear fields, potentially substantially expanding the baryon acoustic oscillations and redshift space distortions information content of dense large scale structure surveys, including for example SDSS main sample and 21 cm intensity mapping initiatives.

  17. Causal Reconstruction

    Science.gov (United States)

    1993-02-01

    suitable source of core events supporting causal reconstruction in a range of domains might be a combination of bodily - kinesthetic and simple...suggested in the previ- ous section, a good place to start might be with causal situations involving bodily - kinesthetic events or simple mechanical events...ANIZATION NAME(S) AND ADDRESS(LS) tý PJIfORMIN’, CRGANIZATION !.LPDRT NUMBEK Artificial Intelligence Laboratory 545 Technology Square AIM 1403 Cambridge

  18. Inflation with a graceful exit in a random landscape

    Energy Technology Data Exchange (ETDEWEB)

    Pedro, F.G. [Univ. Autonoma de Madrid (Spain). Dept. de Fisica Teorica y Inst. de Fisica Teorica UAM/CSIC; Westphal, A. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany). Theory Group

    2016-11-15

    We develop a stochastic description of small-field inflationary histories with a graceful exit in a random potential whose Hessian is a Gaussian random matrix as a model of the unstructured part of the string landscape. The dynamical evolution in such a random potential from a small-field inflation region towards a viable late-time de Sitter (dS) minimum maps to the dynamics of Dyson Brownian motion describing the relaxation of non-equilibrium eigenvalue spectra in random matrix theory. We analytically compute the relaxation probability in a saddle point approximation of the partition function of the eigenvalue distribution of the Wigner ensemble describing the mass matrices of the critical points. When applied to small-field inflation in the landscape, this leads to an exponentially strong bias against small-field ranges and an upper bound N<<10 on the number of light fields N participating during inflation from the non-observation of negative spatial curvature.

  19. Spanish exit polls. Sampling error or nonresponse bias?

    Directory of Open Access Journals (Sweden)

    Pavía, Jose M.

    2016-09-01

    Full Text Available Countless examples of misleading forecasts on behalf of both pre-election and exit polls can be found all over the world. Non-representative samples due to differential nonresponse have been claimed as being the main reason for inaccurate exit-poll projections. In real inference problems, it is seldom possible to compare estimates and true values. Electoral forecasts are an exception. Comparisons between estimates and final outcomes can be carried out once votes have been tallied. In this paper, we examine the raw data collected in seven exit polls conducted in Spain and test the likelihood that the data collected in each sampled voting location can be considered as a random sample of actual results. Knowing the answer to this is relevant for both electoral analysts and forecasters as, if the hypothesis is rejected, the shortcomings of the collected data would need amending. Analysts could improve the quality of their computations by implementing local correction strategies. We find strong evidence of nonsampling error in Spanish exit polls and evidence that the political context matters. Nonresponse bias is larger in polarized elections and in a climate of fearExiste un gran número de ejemplos de predicciones inexactas obtenidas a partir tanto de encuestas pre-electorales como de encuestas a pie de urna a lo largo del mundo. La presencia de tasas de no-respuesta diferencial entre distintos tipos de electores ha sido la principal razón esgrimida para justificar las proyecciones erróneas en las encuestas a pie de urna. En problemas de inferencia rara vez es posible comparar estimaciones y valores reales. Las predicciones electorales son una excepción. La comparación entre estimaciones y resultados finales puede realizarse una vez los votos han sido contabilizados. En este trabajo, examinamos los datos brutos recogidos en siete encuestas a pie de urna realizadas en España y testamos la hipótesis de que los datos recolectados en cada punto

  20. High-Flow Jet Exit Rig Designed and Fabricated

    Science.gov (United States)

    Buehrle, Robert J.; Trimarchi, Paul A.

    2003-01-01

    The High-Flow Jet Exit Rig at the NASA Glenn Research Center is designed to test single flow jet nozzles and to measure the appropriate thrust and noise levels. The rig has been designed for the maximum hot condition of 16 lbm/sec of combustion air at 1960 R (maximum) and to produce a maximum thrust of 2000 lb. It was designed for cold flow of 29.1 lbm/sec of air at 530 R. In addition, it can test dual-flow nozzles (nozzles with bypass flow in addition to core flow) with independent control of each flow. The High- Flow Jet Exit Rig was successfully fabricated in late 2001 and is being readied for checkout tests. The rig will be installed in Glenn's Aeroacoustic Propulsion Laboratory. The High-Flow Jet Exit Rig consists of the following major components: a single component force balance, the natural-gas-fueled J-79 combustor assembly, the plenum and manifold assembly, an acoustic/instrumentation/seeding (A/I/S) section, a table, and the research nozzles. The rig will be unique in that it is designed to operate uncooled. The structure survives the 1960 R test condition because it uses carefully selected high temperature alloy materials such as Hastelloy-X. The lower plenum assembly was designed to operate at pressures to 450 psig at 1960 R, in accordance with the ASME B31.3 piping code. The natural gas-fueled combustor fires directly into the lower manifold. The hot air is directed through eight 1-1/2-in. supply pipes that supply the upper plenum. The flow is conditioned in the upper plenum prior to flowing to the research nozzle. The 1-1/2-in. supply lines are arranged in a U-shaped design to provide for a flexible piping system. The combustor assembly checkout was successfully conducted in Glenn's Engine Component Research Laboratory in the spring of 2001. The combustor is a low-smoke version of the J79 combustor used to power the F4 Phantom military aircraft. The natural gas-fueled combustor demonstrated high-efficiency combustion over a wide range of operating

  1. Disfunção do homoenxerto pulmonar utilizado na reconstrução do trato de saída do ventrículo direito Disfunción del homoinjerto pulmonar utilizado en la reconstrucción del tracto de salida del ventrículo derecho Dysfunction of the pulmonary homograft used in the reconstruction of the right ventricle exit tract

    Directory of Open Access Journals (Sweden)

    Andréa Weirich Lenzi

    2011-01-01

    . RESULTADOS: La muestra final de 75 pacientes con edad mediana en la cirugía de 22 meses, variando de 1-157 meses, presentó 13 pacientes (17,0% que desarrollaron disfunción del homoinjerto, caracterizado por estenosis o insuficiencia pulmonar grave. El tiempo de ocurrencia entre el implante del homoinjerto y la detección de la disfunción fue de 45 ± 20 meses. Cuando el tamaño del homoinjerto fue menor de 21 mm y el escore Z de la válvula pulmonar fue menor que cero, o mayor que tres, fueron considerados factores de riesgo para la ocurrencia de disfunción. CONCLUSIÓN: El homoinjerto pulmonar de tamaño menor que 21 mm y la válvula pulmonar inadecuada para edad y peso del paciente son factores determinantes para disfunción de la prótesis.BACKGROUND: The pulmonary homograft has been used as an option in the correction of congenital cardiopathy with obstruction of the right ventricle exit tract. The long term results, however, are little satisfactory. OBJECTIVE: Identify the risk factors associated to the dysfunction and the pulmonary homograft failure. METHODS: Study with children submitted to the enlargement of the exit tract of the right ventricle with pulmonary homograft. The clinical, surgical, evolutional and morphological aspects of the prosthesis variables were analyzed as risk factors. RESULTS: The final sample of 75 patients with median age at the surgery of 22 months, varying from 1-157 months, presented 13 patients (17.0% who developed dysfunction of the homograft, characterized by stenosis or severe pulmonary insufficiency. The occurrence time between the homograft implant and the detection of the dysfunction was of 45 ± 20 months. When the size of the homograft was smaller than 21 mm and the Z score of the pulmonary valva is lower than zero, or higher than three, the risk factors were considered for the dysfunction occurrence. CONCLUSION: The pulmonary homograft smaller than 21 mm and the inadequate pulmonary valva for the age and weight of the patient

  2. Modelling guidelines for core exit temperature simulations with system codes

    Energy Technology Data Exchange (ETDEWEB)

    Freixa, J., E-mail: jordi.freixa-terradas@upc.edu [Department of Physics and Nuclear Engineering, Technical University of Catalonia (UPC) (Spain); Paul Scherrer Institut (PSI), 5232 Villigen (Switzerland); Martínez-Quiroga, V., E-mail: victor.martinez@nortuen.com [Department of Physics and Nuclear Engineering, Technical University of Catalonia (UPC) (Spain); Zerkak, O., E-mail: omar.zerkak@psi.ch [Paul Scherrer Institut (PSI), 5232 Villigen (Switzerland); Reventós, F., E-mail: francesc.reventos@upc.edu [Department of Physics and Nuclear Engineering, Technical University of Catalonia (UPC) (Spain)

    2015-05-15

    Highlights: • Core exit temperature is used in PWRs as an indication of core heat up. • Modelling guidelines of CET response with system codes. • Modelling of heat transfer processes in the core and UP regions. - Abstract: Core exit temperature (CET) measurements play an important role in the sequence of actions under accidental conditions in pressurized water reactors (PWR). Given the difficulties in placing measurements in the core region, CET readings are used as criterion for the initiation of accident management (AM) procedures because they can indicate a core heat up scenario. However, the CET responses have some limitation in detecting inadequate core cooling and core uncovery simply because the measurement is not placed inside the core. Therefore, it is of main importance in the field of nuclear safety for PWR power plants to assess the capabilities of system codes for simulating the relation between the CET and the peak cladding temperature (PCT). The work presented in this paper intends to address this open question by making use of experimental work at integral test facilities (ITF) where experiments related to the evolution of the CET and the PCT during transient conditions have been carried out. In particular, simulations of two experiments performed at the ROSA/LSTF and PKL facilities are presented. The two experiments are part of a counterpart exercise between the OECD/NEA ROSA-2 and OECD/NEA PKL-2 projects. The simulations are used to derive guidelines in how to correctly reproduce the CET response during a core heat up scenario. Three aspects have been identified to be of main importance: (1) the need for a 3-dimensional representation of the core and Upper Plenum (UP) regions in order to model the heterogeneity of the power zones and axial areas, (2) the detailed representation of the active and passive heat structures, and (3) the use of simulated thermocouples instead of steam temperatures to represent the CET readings.

  3. Using Exit Charts to Develop an Early Stopping Criterion for Turbo Decoding

    OpenAIRE

    Potman, J.; Hoeksema, F.W.; Slump, Cornelis H.

    2004-01-01

    Early stopping criteria are used to determine when additional decoder iterations result in little or no improvement in the bit- error-rate (BER) at the output of a Turbo decoder. This paper proposes a stopping criterion based on Extrinsic Information Transfer (EXIT) charts. The generation and properties of EXIT charts are discussed. Convergence and BER predictions obtained using EXIT charts are compared to results obtained using Turbo decoder simulation. Finally this paper describes the use o...

  4. The Effect of Focusing and Caustics on Exit Phenomena in Systems Lacking Detailed Balance

    CERN Document Server

    Maier, R S; Maier, Robert S.; Stein, Daniel L.

    1993-01-01

    We study the trajectories followed by a particle subjected to weak noise when escaping from the domain of attraction of a stable fixed point. If detailed balance is absent, a _focus_ may occur along the most probable exit path, leading to a breakdown of symmetry (if present). The exit trajectory bifurcates, and the exit location distribution may become `skewed' (non-Gaussian). The weak-noise asymptotics of the mean escape time are strongly affected. Our methods extend to the study of skewed exit location distributions in stochastic models without symmetry.

  5. Exit site care in the Netherlands: the use of guidelines in practice.

    Science.gov (United States)

    Hoekstra, Bettie P; de Vries-Hoogsteen, Anneke; Winkels, Bieneke; Zevenbergen-Osinga, Helma; Thijssen-Broers, Ingrid; Bellemakers, Trian

    2017-09-01

    The aim of this paper is to describe the quality of exit site care by evaluating the use of the Dutch exit site guideline over a period of 15 years. The special interest group (SIG) for peritoneal dialysis (PD) analysed results of three surveys concerning general exit site care among members of the Dutch Association for nurses and carers (V&VN), the dialysis and nephrology section. In 2002 (when no guidelines were available) the survey showed huge diversity in practice, with no definition of the post-operative period after catheter placement and no uniform monitoring of the exit site. There was a difference in use of dressings and exit site care. In 2009, the survey showed that most dialysis centres worked with the first guideline of the V&VN (2006) and exit site classification (2006). However, at this time, there was still diversity in the way exit site care was undertaken. In 2016, there was widespread use of guidelines and classification alongside a more individual approach to practice. Differences occured in use of disinfectant, antimicrobial ointment, swimming and going to the sauna. The exit site guideline has been widely used in the Netherlands, improving quality in care and utilising a more individual patient approach in care. However, there are still differences identified in practice for which the evidence-base and evaluation will be undertaken to supplement the guideline and attribute to exit site care practice. © 2017 European Dialysis and Transplant Nurses Association/European Renal Care Association.

  6. Influence of drill helical direction on exit damage development in drilling carbon fiber reinforced plastic

    Science.gov (United States)

    Bai, Y.; Jia, Z. Y.; Wang, F. J.; Fu, R.; Guo, H. B.; Cheng, D.; Zhang, B. Y.

    2017-06-01

    Drilling is inevitable for CFRP components’ assembling process in the aviation industry. The exit damage frequently occurs and affects the load carrying capacity of components. Consequently, it is of great urgency to enhance drilling exit quality on CFRP components. The article aims to guide the reasonable choice of drill helical direction and effectively reduce exit damage. Exit observation experiments are carried out with left-hand helical, right-hand helical and straight one-shot drill drilling T800S CFRP laminates separately. The development rules of exit damage and delamination factor curves are obtained. Combined with loading conditions and fracture modes of push-out burrs, and thrust force curves, the influence of drill helical direction on exit damage development is derived. It is found that the main fracture modes for left-hand helical, right-hand helical, and straight one-shot drill are mode I, extrusive fracture, mode III respectively. Among them, mode III has the least effect on exit damage development. Meanwhile, the changing rate of thrust force is relative slow for right-hand helical and straight one-shot drill in the thrust force increasing phase of stage II, which is disadvantaged for exit damage development. Therefore, straight one-shot drill’s exit quality is the best.

  7. Design and evaluation of single and dual flow thrust vector nozzles with post exit vanes

    Science.gov (United States)

    Carpenter, Thomas W.; Vaccarezza, Stephen E.; Dobbins, Sean

    1992-01-01

    This Thrust Vectored Research project required that a 1/24 scale model of the F/A-18 High Alpha Research Vehicle, (HARV), propulsion system be constructed on the university campus. This propulsion system was designed for cold flow testing on a multicomponent test rig. Forces and moments were measured to study nozzle performance parameters. The flow visualization technique of color Schlieren photography was performed to investigate the flow phenomena at the nozzle exit. The flow interactions that were identified consisted of vane nozzleing between the outer and lower vanes and vane tip interference. The thrust vectoring system consisted of three asymmetrically spaced vanes installed circumferentially on a maximum afterburner nozzle. The performance of the nozzle was investigated with the outer and lower vanes equally deflected, (-10 deg is less than delta(sub v) is less than 25 deg), and with the upper vane fully retracted, (delta(sub v) equals -10 deg). The nozzle pressure ratio ranged from 4 to 6. The results indicated that a vane nozzleing effect developed at nozzle pressure ratios of 4 and 6 when the outer and lower vanes were deflected far enough into the flow field such that the increase in vane area accelerated the flow past the vanes causing distorted shock waves. This accelerated flow was a result of a pressure differential existing between the inside surface of the vane and the ambient pressure. The stagnation pressure that developed along the inside surface of the vane accelerated the flow past the vanes causing it to equalize with ambient pressure, thus providing distorted shock waves. A tip interference was present at the trailing edge of the upper vane as a result of low nozzle pressure, NPR 4, with high vane deflection, delta(sub v) equals 25 degrees, and also with a high nozzle pressure, NPR 6, and low vane deflections, delta(sub v) equals 15 degrees.

  8. Motor axons are guided to exit points in the spinal cord by Slit and Netrin signals.

    Science.gov (United States)

    Kim, Minkyung; Fontelonga, Tatiana M; Lee, Clare H; Barnum, Sarah J; Mastick, Grant S

    2017-12-01

    In the spinal cord, motor axons project out the neural tube at specific exit points, then bundle together to project toward target muscles. The molecular signals that guide motor axons to and out of their exit points remain undefined. Since motor axons and their exit points are located near the floor plate, guidance signals produced by the floor plate and adjacent ventral tissues could influence motor axons as they project toward and out of exit points. The secreted Slit proteins are major floor plate repellents, and motor neurons express two Slit receptors, Robo1 and Robo2. Using mutant mouse embryos at early stages of motor axon exit, we found that motor exit points shifted ventrally in Robo1/2 or Slit1/2 double mutants. Along with the ventral shift, mutant axons had abnormal trajectories both within the neural tube toward the exit point, and after exit into the periphery. In contrast, the absence of the major ventral attractant, Netrin-1, or its receptor, DCC caused motor exit points to shift dorsally. Netrin-1 attraction on spinal motor axons was demonstrated by in vitro explant assays, showing that Netrin-1 increased outgrowth and attracted cultured spinal motor axons. The opposing effects of Slit/Robo and Netrin-1/DCC signals were tested genetically by combining Netrin-1 and Robo1/2 mutations. The location of exit points in the combined mutants was significantly recovered to their normal position compared to Netrin-1 or Robo1/2 mutants. Together, these results suggest that the proper position of motor exit points is determined by a "push-pull" mechanism, pulled ventrally by Netrin-1/DCC attraction and pushed dorsally by Slit/Robo repulsion. Copyright © 2017 Elsevier Inc. All rights reserved.

  9. 3D color reconstructions in single DMD holographic display with LED source and complex coding scheme

    Science.gov (United States)

    Chlipała, Maksymilian; Kozacki, Tomasz

    2017-06-01

    In the paper we investigate the possibility of color reconstructions of holograms with a single DMD and incoherent LED source illumination. Holographic display is built with 4F imaging system centering reconstruction volume around the DMD surface. The display design employs complex coding scheme, which allows reconstructing complex wave from a binary hologram. In order to improve the quality of reconstructed holograms time multiplexing method is used. During the optical reconstructions we analyze quality of reconstructed holograms with incoherent RGB light sources as a function of reconstruction distance, present the possibility of 3D hologram reconstruction, and investigate temporal coherence effects in holographic display with the DMD.

  10. Non-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cells.

    Directory of Open Access Journals (Sweden)

    Kathleen A Estes

    2011-09-01

    Full Text Available The intestine is a common site for invasion by intracellular pathogens, but little is known about how pathogens restructure and exit intestinal cells in vivo. The natural microsporidian parasite N. parisii invades intestinal cells of the nematode C. elegans, progresses through its life cycle, and then exits cells in a transmissible spore form. Here we show that N. parisii causes rearrangements of host actin inside intestinal cells as part of a novel parasite exit strategy. First, we show that N. parisii infection causes ectopic localization of the normally apical-restricted actin to the basolateral side of intestinal cells, where it often forms network-like structures. Soon after this actin relocalization, we find that gaps appear in the terminal web, a conserved cytoskeletal structure that could present a barrier to exit. Reducing actin expression creates terminal web gaps in the absence of infection, suggesting that infection-induced actin relocalization triggers gap formation. We show that terminal web gaps form at a distinct stage of infection, precisely timed to precede spore exit, and that all contagious animals exhibit gaps. Interestingly, we find that while perturbations in actin can create these gaps, actin is not required for infection progression or spore formation, but actin is required for spore exit. Finally, we show that despite large numbers of spores exiting intestinal cells, this exit does not cause cell lysis. These results provide insight into parasite manipulation of the host cytoskeleton and non-lytic escape from intestinal cells in vivo.

  11. Visual Barriers to Prevent Ambulatory ALzheimer's Patients from Exiting through an Emergency Door.

    Science.gov (United States)

    Namazi, Kevan H.; And Others

    1989-01-01

    Conducted study on Alzheimer's unit to test seven different visual barrier conditions for reducing patient exits. Findings indicated that exiting was eliminated under two conditions. Results suggest visual agnosia, the inability to interpret what the eye sees, may be used as tool in managing wandering behavior of Alzheimer's patients. (Author/NB)

  12. Exit pupil expander: image quality performance enhancements and environmental testing results

    Science.gov (United States)

    Powell, Karlton D.; Lopez, Peggy A.; Malik, Amjad

    2003-09-01

    The numerical aperture of the light emanating from display pixels in a given display system determines the exit pupil size. In retinal scanning displays, the exit pupil is defined by the scanner optics, creating a rastered, projected image at an intermediate plane, typically resulting in an exit pupil approximately the size of an eye's pupil. Positional freedom of the eye and relative display placement define the required expansion of the limited input NA for producing the desired exit pupil size for the display system. Currently Microvision utilizes an optical element comprised of two Microlens Arrays (MLAs) in tandem to expand the NA. The dual-MLA system has demonstrated exit pupil size that is independent of color; and uniformity of the beamlet structure is quite Top-Hat like. To further improve the perceived image quality, Microvision has now refined the optical system to minimize interference effects in the Exit Pupil plane that were caused by the coherent nature of the light source. We describe here a single refractive double-sided aspheric element that diminishes this interference effect by converting an input Gaussian beam profile to a Top-Hat profile. We also discuss the theory behind the use of a Gaussian-to-Top-Hat Converter, the tradeoffs associated with its use, as well as experimental results showing the uniformity improvements when using a Top-Hat converter element in conjunction with the MLA-based Exit Pupil Expander. In addition, we report the progress of environmental testing of the Exit Pupil Expander (EPE).

  13. Effect of cattle temperament as determined by exit velocity on lung respiratory lesions and liver disease

    Science.gov (United States)

    The objective of this trial was to use exit velocity as a means of determining temperament of cattle to evaluate the impact of temperament on animal health. At the time of processing, exit velocity and body weight were recorded on 20 pens of cattle (2,877 head) at a commercial feedlot. Infrared sens...

  14. 14 CFR 91.607 - Emergency exits for airplanes carrying passengers for hire.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 2 2010-01-01 2010-01-01 false Emergency exits for airplanes carrying... Emergency exits for airplanes carrying passengers for hire. (a) Notwithstanding any other provision of this chapter, no person may operate a large airplane (type certificated under the Civil Air Regulations...

  15. Scholars Probe Diverse Effects of Exit Exams: State Graduation Tests Found to Hit Certain Groups Harder

    Science.gov (United States)

    Viadero, Debra

    2009-01-01

    A study released last week suggesting that California's high school exit exams are affecting some student demographic groups more than others is the latest in a small spate of studies pointing to trade-offs from policies that require high school students to pass state tests to graduate. Twenty-six states have exit exams in place or will by 2012,…

  16. The Exit Interview as Monitor for Change: A Review of Literature.

    Science.gov (United States)

    Schmidt, Wallace V.

    The exit interview, while widely practiced, has been largely ignored as an instrument for organizational change. A review of the literature reveals that eight out of ten firms in the United States use exit interviews to control attrition and identify areas where changes need to be instituted. Persuading an employee to tell the truth about why he…

  17. Private wealth and job exit at older age: a random effects model

    NARCIS (Netherlands)

    Bloemen, H.G.

    2016-01-01

    Private wealth holdings are likely to become an increasingly important determinant in the job exit decision of elderly workers. Net wealth may correlate with worker’s characteristics that also determine the exit out of a job. It is therefore important to include a rich set of observed

  18. Wives' Relative Wages, Husbands' Paid Work Hours, and Wives' Labor-Force Exit

    Science.gov (United States)

    Shafer, Emily Fitzgibbons

    2011-01-01

    Economic theories predict that women are more likely to exit the labor force if their partners' earnings are higher and if their own wage rate is lower. In this article, I use the National Longitudinal Survey of Youth (N = 2,254) and discrete-time event-history analysis to show that wives' relative wages are more predictive of their exit than are…

  19. Thermal regime, predation danger and the early marine exit of sockeye salmon Oncorhynchus nerka

    NARCIS (Netherlands)

    Katinic, P.J.; Patterson, D.A.; Ydenberg, R.C.

    2015-01-01

    Marine exit timing of sockeye salmon Oncorhynchus nerka populations on the Haida Gwaii Archipelago, British Columbia, Canada, is described, with specific focus on Copper Creek. Marine exit in Copper Creek occurs¿>¿130¿days prior to spawning, one of the longest adult freshwater residence periods

  20. Effects of Generational Competition and Substitution on Late Labour Participation and Labour Market Exit from a Multilevel Perspective

    Directory of Open Access Journals (Sweden)

    Henriette Engelhardt

    2013-12-01

    Full Text Available In this paper, we investigate the effects of demographic, economic and labour market structures on labour market participation and on the transition to inactivity (exit for older males in eleven European countries. Theoretically, our analysis is guided by considerations of intragenerational competition and intergenerational substitution. Following Easterlin’s hypothesis that intragenerational competition rises with cohort size, we assume a negative effect of cohort size on labour market participation and a positive effect on early exit from the labour market. Taking into account that different cohorts are substitutes at least to a certain extent, we assume that the probability of an early exit will be reduced by a high intergenerational exchange ratio in favour of older workers. Thus, labour market participation is influenced by the populations’ age structure both when entering the labour force and during the career. Moreover, low shares of graduates in older cohorts are expected to reduce older workers’ chances of labour market participation. In addition to demographic structures, general economic conditions, such as per capita GDP and its development over time, act both to further and to hamper the employment of older workers. Additionally, labour market structures, such as unemployment rates, the extent of part-time work or the amount of service jobs influence individual participation and the transition to inactivity. To test these hypotheses, we use merged data from the first two waves of SHARE and macro-level indicators from Eurostat. We estimate a two-level random-intercept logit model which allows us to determine the share of variance in international late careers that can be attributed to country-specific factors and can quantify the relative impact of specific socio-demographic and socio-economic backgrounds. Our results imply that cross-national variance in labour market participation is mainly driven by the instance of long

  1. Inflation with a graceful exit in a random landscape

    Energy Technology Data Exchange (ETDEWEB)

    Pedro, F.G. [Departamento de Física Teórica and Instituto de Física Teórica UAM/CSIC,Universidad Autónoma de Madrid,Cantoblanco, 28049 Madrid (Spain); Westphal, A. [Deutsches Elektronen-Synchrotron DESY, Theory Group,D-22603 Hamburg (Germany)

    2017-03-30

    We develop a stochastic description of small-field inflationary histories with a graceful exit in a random potential whose Hessian is a Gaussian random matrix as a model of the unstructured part of the string landscape. The dynamical evolution in such a random potential from a small-field inflation region towards a viable late-time de Sitter (dS) minimum maps to the dynamics of Dyson Brownian motion describing the relaxation of non-equilibrium eigenvalue spectra in random matrix theory. We analytically compute the relaxation probability in a saddle point approximation of the partition function of the eigenvalue distribution of the Wigner ensemble describing the mass matrices of the critical points. When applied to small-field inflation in the landscape, this leads to an exponentially strong bias against small-field ranges and an upper bound N≪10 on the number of light fields N participating during inflation from the non-observation of negative spatial curvature.

  2. Exit Noise Summer Fest: Explaining the audience in ethnographic discourse

    Directory of Open Access Journals (Sweden)

    Lukić-Krstanović Miroslava M.

    2005-01-01

    Full Text Available In Ethnology, studying festivals is a relevant activity since it could enlighten a number of complex cultural and social processes. The festivals represent public events, public ceremonies, cluster of rituals and produce many symbols, and as such, they are in fact a creative reflection of a society. In this paper, we analyze the Exit Noise Summer Fest, the biggest music festival in SE Europe. The aim of the analysis is to gain understanding of the cultural event of this kind and its protagonists, namely, the audience. Shedding a light to a music spectacle, from a standpoint of social and symbolic communication, directs to a different perspective in reading of rituals, communities zones, and semantic constructions of noise and body in the center of ritual behaviors. The research shows that the music experience and atmosphere of the celebration, though having somewhat unclear ritual borderline and zone, are compatible with the daily culture and social processes, in which the event is created and further reflects itself through various mediums.

  3. Entrance and Exit CSR Impedance for Non-Ultrarelativistic Beam

    Energy Technology Data Exchange (ETDEWEB)

    Li, Rui; Tsai, Cheng Ying [SLAC National Accelerator Lab., Menlo Park, CA (United States); Virginia Polytechnic Inst. and State Univ. (Virginia Tech), Blacksburg, VA (United States)

    2017-05-01

    For a high-brightness electron beam being transported through beamlines involving bending systems, the coherent synchrotron radiation (CSR) and longitudinal space charge (LSC) interaction could often cause microbunching instability. The semi-analytical Vlasov solver for microbunching gain* depends on the impedances for the relevant collective effects. The existing results for CSR impedances are usually obtained for the ultrarelativistic limit. To extend the microbunching analysis to cases of low energies, such as the case of an ERL merger, or to density modulations at extremely small wavelength, it is necessary to extend the impedance analysis to the non-ultrarelativistic regime. In this study, we present the impedance analysis for the transient CSR interaction in the non-ultrarelativistic regime, for transients including both entrance to and exit from a magnetic dipole. These impedance results will be compared to their ultra-relativistic counterparts**, and the corresponding wakefield obtained from the impedance for low-energy beams will be compared with the existing results of transient CSR wakefield for general beam energies***.

  4. Inflation with a graceful exit in a random landscape

    Science.gov (United States)

    Pedro, F. G.; Westphal, A.

    2017-03-01

    We develop a stochastic description of small-field inflationary histories with a graceful exit in a random potential whose Hessian is a Gaussian random matrix as a model of the unstructured part of the string landscape. The dynamical evolution in such a random potential from a small-field inflation region towards a viable late-time de Sitter (dS) minimum maps to the dynamics of Dyson Brownian motion describing the relaxation of non-equilibrium eigenvalue spectra in random matrix theory. We analytically compute the relaxation probability in a saddle point approximation of the partition function of the eigenvalue distribution of the Wigner ensemble describing the mass matrices of the critical points. When applied to small-field inflation in the landscape, this leads to an exponentially strong bias against small-field ranges and an upper bound N ≪ 10 on the number of light fields N participating during inflation from the non-observation of negative spatial curvature.

  5. Studi Kasus Yayasan X: Analisa Hasil Exit Questionnaire Survey

    Directory of Open Access Journals (Sweden)

    Bernadetta Junita Santosa

    2011-04-01

    Full Text Available This case study on the X Foundation aims to provide an overview and analysis of questionnaire results of exit interviews of employees who came out in 2009 and 2010. This case study was conducted on the basis of the importance of seeing the dimensions or factors that exist, particularly with regard to the factors of satisfaction or dissatisfaction in the employee working within the Organization. The study was conducted using quantitative methods with retrieval of primary data on the X Foundation, the descriptive method. Subjects were 63 employees who came out in 2009 and 125 employees that came out in 2010 at differing position, level and status. The results generally showed that there are two factors that should motivate employees to be the opposite that is causing dissatisfaction in the employee, and there are two factors also confirm the reasons why an employee becomes dissatisfied and decided to leave the organization. The suggestions put forward to conduct further research to further deepen the analysis of descriptive statistics, so the depiction becomes more profound; and can provide accurate advice to the organization. 

  6. Dropped out or pushed out? Insurance market exit and provider market power in Medicare Advantage.

    Science.gov (United States)

    Pelech, Daria

    2017-01-01

    This paper explores how provider and insurer market power affect which markets an insurer chooses to operate in. A 2011 policy change required that certain private insurance plans in Medicare form provider networks de novo; in response, insurers cancelled two-thirds of the affected plans. Using detailed data on pre-policy provider and insurer market structure, I compare markets where insurers built networks to those they exited. Overall, insurers in the most concentrated hospital and physician markets were 9 and 13 percentage points more likely to exit, respectively, than those in the least concentrated markets. Conversely, insurers with more market power were less likely to exit than those with less, and an insurer's market power had the largest effect on exit in concentrated hospital markets. These findings suggest that concentrated provider markets contribute to insurer exit and that insurers with less market power have more difficulty surviving in concentrated provider markets. Published by Elsevier B.V.

  7. Aggregating job exit statuses of a plurality of compute nodes executing a parallel application

    Science.gov (United States)

    Aho, Michael E.; Attinella, John E.; Gooding, Thomas M.; Mundy, Michael B.

    2015-07-21

    Aggregating job exit statuses of a plurality of compute nodes executing a parallel application, including: identifying a subset of compute nodes in the parallel computer to execute the parallel application; selecting one compute node in the subset of compute nodes in the parallel computer as a job leader compute node; initiating execution of the parallel application on the subset of compute nodes; receiving an exit status from each compute node in the subset of compute nodes, where the exit status for each compute node includes information describing execution of some portion of the parallel application by the compute node; aggregating each exit status from each compute node in the subset of compute nodes; and sending an aggregated exit status for the subset of compute nodes in the parallel computer.

  8. Axial Super-resolution Evanescent Wave Tomography

    CERN Document Server

    Pendharker, Sarang; Newman, Ward; Ogg, Stephen; Nazemifard, Neda; Jacob, Zubin

    2016-01-01

    Optical tomographic reconstruction of a 3D nanoscale specimen is hindered by the axial diffraction limit, which is 2-3 times worse than the focal plane resolution. We propose and experimentally demonstrate an axial super-resolution evanescent wave tomography (AxSET) method that enables the use of regular evanescent wave microscopes like Total Internal Reflection Fluorescence Microscope (TIRF) beyond surface imaging, and achieve tomographic reconstruction with axial super-resolution. Our proposed method based on Fourier reconstruction achieves axial super-resolution by extracting information from multiple sets of three-dimensional fluorescence images when the sample is illuminated by an evanescent wave. We propose a procedure to extract super-resolution features from the incremental penetration of an evanescent wave and support our theory by 1D (along the optical axis) and 3D simulations. We validate our claims by experimentally demonstrating tomographic reconstruction of microtubules in HeLa cells with an axi...

  9. Reconstructing Normality

    DEFF Research Database (Denmark)

    Gildberg, Frederik Alkier; Bradley, Stephen K.; Fristed, Peter Billeskov

    2012-01-01

    Forensic psychiatry is an area of priority for the Danish Government. As the field expands, this calls for increased knowledge about mental health nursing practice, as this is part of the forensic psychiatry treatment offered. However, only sparse research exists in this area. The aim of this study...... was to investigate the characteristics of forensic mental health nursing staff interaction with forensic mental health inpatients and to explore how staff give meaning to these interactions. The project included 32 forensic mental health staff members, with over 307 hours of participant observations, 48 informal...... interviews, and seven semistructured interviews. The findings show that staff interaction is typified by the use of trust and relationship-enabling care, which is characterized by the establishment and maintenance of an informal, trusting relationship through a repeated reconstruction of normality...

  10. Frozen waves: experimental generation

    OpenAIRE

    Vieira, TA; Gesualdi, MRR; Zamboni-Rached, M

    2012-01-01

    Frozen waves (FWs) are very interesting particular cases of nondiffracting beams whose envelopes are static and whose longitudinal intensity patterns can be chosen a priori. We present here for the first time (that we know of) the experimental generation of FWs. The experimental realization of these FWs was obtained using a holographic setup for the optical reconstruction of computer generated holograms (CGH), based on a 4-f Fourier filtering system and a nematic liquid crystal spatial light ...

  11. Migration ecology and stopover population size of Red Knots Calidris canutus rufa at Mingan Archipelago after exiting the breeding grounds

    Science.gov (United States)

    Lyons, James E.; Baker, Allan J.; González, Patricia M.; Aubry, Yves; Buidin, Christophe; Rochepault, Yann

    2018-01-01

    Populations of migratory birds present unique conservation challenges given the often vast distances separating critical resources throughout the annual cycle. Migration areas close to the breeding grounds represent a link between two key stages of the annual cycle, and understanding migration ecology as birds exit the breeding grounds may be particularly informative for successful conservation. We studied migration phenology and stopover ecology of an endangered subspecies of the Red Knot Calidris canutus rufa at a migration area relatively close to its breeding range. Using mark-recapture/resight data and a Jolly-Seber model for open populations, we described the arrival and departure schedules, stopover duration, and passage population size at the Mingan Archipelago, Quebec, Canada. Red Knots arrived at the study area in two distinct waves of birds separated by approximately 22 days. Nearly 30% of the passage population arrived in the first wave of arrivals during 15–18 July, and approximately 22% arrived in a second wave during 8–11 August. The sex-ratio in the stopover population at the time of the first wave was slightly skewed toward females, whereas the second wave was heavily skewed toward males. Because males remain on the breeding grounds to care for young, this may reflect successfulbreeding in the year of our study. The estimated stopover duration (population mean) was 11 days (95% credible interval: 10.3–11.7 days), but stopover persistence was variable throughout the season. We estimated a passage population size of 9,450 birds (8,355–10,710), a minimum estimate for reasons related to the duration of our sampling. Mingan Archipelago is thus an important migration area for this endangered subspecies and could be a priority in conservation planning. Our results also emphasize the advantages of mark-recapture/resight approaches for estimating migration phenology and stopover persistence.

  12. Skeletonized wave equation of surface wave dispersion inversion

    KAUST Repository

    Li, Jing

    2016-09-06

    We present the theory for wave equation inversion of dispersion curves, where the misfit function is the sum of the squared differences between the wavenumbers along the predicted and observed dispersion curves. Similar to wave-equation travel-time inversion, the complicated surface-wave arrivals in traces are skeletonized as simpler data, namely the picked dispersion curves in the (kx,ω) domain. Solutions to the elastic wave equation and an iterative optimization method are then used to invert these curves for 2D or 3D velocity models. This procedure, denoted as wave equation dispersion inversion (WD), does not require the assumption of a layered model and is less prone to the cycle skipping problems of full waveform inversion (FWI). The synthetic and field data examples demonstrate that WD can accurately reconstruct the S-wave velocity distribution in laterally heterogeneous media.

  13. Electromagnetic Waves

    DEFF Research Database (Denmark)

    This book is dedicated to various aspects of electromagnetic wave theory and its applications in science and technology. The covered topics include the fundamental physics of electromagnetic waves, theory of electromagnetic wave propagation and scattering, methods of computational analysis...

  14. Dual Waves

    OpenAIRE

    Kallosh, Renata

    1994-01-01

    We study the gravitational waves in the 10-dimensional target space of the superstring theory. Some of these waves have unbroken supersymmetries. They consist of Brinkmann metric and of a 2-form field. Sigma-model duality is applied to such waves. The corresponding solutions we call dual partners of gravitational waves, or dual waves. Some of these dual waves upon Kaluza-Klein dimensional reduction to 4 dimensions become equivalent to the conformo-stationary solutions of axion-dilaton gravity...

  15. How to make a graceful exit from the merchant function

    Energy Technology Data Exchange (ETDEWEB)

    Holder, J. [Consumers Gas Co. Ltd., North York, ON (Canada)

    1998-09-01

    The impact that deregulation and convergence has had on local distribution companies (LDCs) was discussed. LDCs are getting out of a whole range of business activities, or are turning some of them into new entities while transferring others to affiliates. At the other end of the spectrum, Consumers Gas, Canada`s largest LDC, has moved from a gas distribution and an oil pipeline company to becoming a total energy provider. The changes at Consumers Gas began with the Halloween agreement which was based on the following four basic principles: (1) better access for Canadian buyers to gas supply, (2) better access for Canadian producers to gas markets, (3) protection for Canadian consumers for reasonable, foreseeable gas requirements, and (4) a commitment to create a competitive natural gas market in Canada. At the same time, several small niche market players have entered the retail market to compete with large producers such as Sunoco and Shell. Ontario also saw the arrival of large marketers such as Enron, and the development of an active direct purchase market. Today, 65 per cent of the volume of natural gas transport is on behalf of direct purchase customers. The next phase of deregulation was also looked at, focusing primarily on the growing problems with the current regulated local distribution companies` gas supply options and the resulting price volatility and uncertainty due to an increase of direct purchase activity. Various possible ways to resolve this problem are explored, including exiting the merchant function, i.e. to change from an obligation to supply gas to an obligation to deliver gas, all the while ensuring that the consumer is protected. Other problems, such as convergence, unbundling and rebundling will also have to be dealt with in the next phase of deregulation.

  16. The SSG Wave Energy Converter

    DEFF Research Database (Denmark)

    Vicinanza, Diego; Margheritini, Lucia; Kofoed, Jens Peter

    2012-01-01

    The Sea-wave Slot-cone Generator concept (SSG) is a Wave Energy Converter based on the wave overtopping principle utilizing several reservoirs placed on top of each other, in which the energy of the incoming wave will be stored as potential energy. The water captured in the reservoirs will then run...... through turbines for electricity production. The system utilizes a wide spectrum of different wave conditions by means of multiple reservoirs, located at different levels above the still water level. Thereby, it obtains a high overall efficiency and it can be suitable for shoreline and breakwater...... at the Svaaheia site (Norway), Port of Hanstholm (Denmark) and Port of Garibaldi (Oregon, USA). In the last-mentioned two projects, the Sea-wave Slot-cone Generator technology is integrated into outer harbor breakwater and jetty reconstruction projects. Comprehensive studies have been performed in the last years...

  17. Reconstructive Urology

    Directory of Open Access Journals (Sweden)

    Fikret Fatih Önol

    2014-11-01

    Full Text Available In the treatment of urethral stricture, Buccal Mucosa Graft (BMG and reconstruction is applied with different patch techniques. Recently often prefered, this approach is, in bulber urethra strictures of BMG’s; by “ventral onley”, in pendulous urethra because of thinner spingiosis body, which provides support and nutrition of graft; by means of “dorsal inley” being anastomosis. In the research that Cordon et al. did, they compared conventional BMJ “onley” urethroplast and “pseudo-spongioplasty” which base on periurethral vascular tissues to be nourished by closing onto graft. In repairment of front urethras that spongiosis supportive tissue is insufficient, this method is defined as peripheral dartos [çevre dartos?] and buck’s fascia being mobilized and being combined on BMG patch. Between the years 2007 and 2012, assessment of 56 patients with conventional “ventral onley” BMG urethroplast and 46 patients with “pseudo-spongioplasty” were reported to have similar success rates (80% to 84% in 3.5 year follow-up on average. While 74% of the patients that were applied pseudo-spongioplasty had disease present at distal urethra (pendulous, bulbopendulous, 82% of the patients which were applied conventional onley urethroplast had stricture at proximal (bulber urethra yet. Also lenght of the stricture at the pseudo-spongioplasty group was longer in a statistically significant way (5.8 cm to 4.7 cm on average, p=0.028. This study which Cordon et al. did, shows that conditions in which conventional sponjiyoplasti is not possible, periurethral vascular tissues are adequate to nourish BMG. Even it is an important technique in terms of bringing a new point of view to today’s practice, data especially about complications that may show up after pseudo-spongioplasty usage on long distal strictures (e.g. appearance of urethral diverticulum is not reported. Along with this we think that, providing an oppurtinity to patch directly

  18. Effect of slotted exit orifice on performance of plasma synthetic jet actuator

    Science.gov (United States)

    Zong, Haohua; Kotsonis, Marios

    2017-03-01

    This study experimentally investigates the influence of exit orifice shape on the performance characteristics of a three-electrode plasma synthetic jet actuator. High-speed Schlieren imaging system and phase-locked two-component PIV measurements are used for flowfield characterisation in quiescent conditions. Two actuator configurations with the same exit area but different exit orifice shape (round orifice and slot orifice) are studied. Results indicate a close correspondence between the shapes of the starting vortex ring with the shapes of the respective exit orifices. For the slot orifice, the elongated starting vortex ring gradually expands during propagation, while its ends become warped. A distinct K-H instability structure is observed, inducing continuous oscillation of the high-speed jet. Compared with the jet from the round orifice, the slot jet has a higher entrainment rate of surrounding air, thus resulting in a lower propagation velocity of the jet front. The exit velocity of PSJA within one period initially shows a rapid increase, then persists at a relatively high level (100-130 m/s), and finally drops with some small-scale oscillations. The oscillation amplitude is less than 10 m/s, and the oscillation period is approximately 600 µs. Under conditions of same exit area, orifice shape has little influence on the variation of the exit velocity.

  19. Influences of exit and stair conditions on human evacuation in a dormitory

    Science.gov (United States)

    Lei, Wenjun; Li, Angui; Gao, Ran; Wang, Xiaowei

    2012-12-01

    Evacuation processes of students are investigated by experiment and simulation. The experiment is performed for students evacuating from a dormitory with an exit and stairs. FDS+Evac is proposed to simulate the exit and stair dynamics of occupant evacuation. Concerning the exit and stair widths, we put forward some useful standpoints. Good agreement is achieved between the predicted results and experimental results. With the increase of exit width, a significant stratification phenomenon will be found in flow rate. Stratification phenomenon is that two different stable flow rates will emerge during the evacuation. And the flow rate curve looks like a ladder. The larger the exit width, the earlier the stratification phenomenon appears. When exit width is more than 2.0 m, the flow rate of each exit width is divided into two stable stages, and the evacuation times show almost no change. The judgment that the existence of stairs causes flow stratification is reasonable. By changing the width of the stairs, we proved that judgment. The smaller the width of BC, the earlier the stratification appears. We found that scenario 5 is the most adverse circumstance. Those results are helpful in performance-based design of buildings.

  20. 'The ones that got away': implementing an exit policy for nurses in a public hospital.

    Science.gov (United States)

    Hawkins, Cheryl-Ann; O'Connor, Louise; Potter, Sharee

    2003-08-01

    The shortage of registered nurses in Victoria led a Melbourne metropolitan hospital to analyse their recent staff attrition rate. This analysis highlighted the importance of having an exiting policy in place for all departing staff. An exit policy can provide unique opportunities for hospitals to collect information that may help reduce future employee turnover through the identification of the causes of employee dissatisfaction. This paper will discuss the literature and outline the project that aided in the analysis of the hospital's attrition rate and development of a practical exit policy.

  1. Market entry and exit by biotech and device companies funded by venture capital.

    Science.gov (United States)

    Burns, Lawton R; Housman, Michael G; Robinson, Charles A

    2009-01-01

    Start-up companies in the biotechnology and medical device sectors are important sources of health care innovation. This paper describes the role of venture capital in supporting these companies and charts the growth in venture capital financial support. The paper then uses longitudinal data to describe market entry and exit by these companies. Similar factors are associated with entry and exit in the two sectors. Entries and exits in one sector also appear to influence entry in the other. These findings have important implications for developing innovative technologies and ensuring competitive markets in the life sciences.

  2. VENTURE COMPANY INITIAL PUBLIC OFFERING IN RUSSIA AS A WAY OF EXIT FROM VENTURE FUND

    Directory of Open Access Journals (Sweden)

    L. S. Tchugayeva

    2012-01-01

    Full Text Available Venture companies patronized by venture funds unavoidably face up with the problem of exit out of the fund in order to start independent development. The exit should be made with maximum benefit both for the company and the fund. One of this behavior strategic ways is initial public offering of the venture company (IPO market. An alternative of such exit is a transaction of merging and absorption (M&A market. Main tendencies of the venture IPO market in Russia are discussed along with comparison of this market with that in the USA.

  3. Can exit prizes induce lame ducks to shirk less? Experimental evidence

    Directory of Open Access Journals (Sweden)

    Leif Helland

    2012-12-01

    Full Text Available Elected representatives serving their final period face only weak incentives to provide costly effort. However, overlapping generations (OLG models suggest that exit prizes sustained by trigger strategies can induce representatives in their final period to provide such effort. We evaluate this hypothesis using a simple OLG public good experiment, the central treatment being whether exit prizes are permitted. We find that a significantly higher number of subjects in their final period contribute when exit prizes are permitted. However, this result does not originate from use of trigger strategies. More likely explanations include gift-exchange and focal-point effects.

  4. Reconstruction of the electron diffusion region

    Science.gov (United States)

    Sonnerup, B. U. Ö.; Hasegawa, H.; Denton, R. E.; Nakamura, T. K. M.

    2016-05-01

    We discuss mathematical tools for the reconstruction of two-dimensional, time-independent magnetic field and flow in the electron diffusion region, at a site of antiparallel magnetic reconnection. The basic assumptions are that the ions are stationary and have constant density. The width of the reconnection layer is of the order of the electron gyroradius or the electron inertial length. Our model includes the axial electron pressure term in Ohm's law developed by M. Hesse and coworkers. We demonstrate the feasibility of doing reconstruction of electron magnetohydrodynamic (EMHD) structures for a simplified system with zero electron inertia. The code is benchmarked using an exact solution that has antiparallel unidirectional magnetic fields, plus out-of-plane quadrupolar Hall fields, as well as the expected slow electron inflow and rapid exit jets. The inertialess reconstruction is then applied to synthetic data from a 2-D, particle-in-cell, simulation of antiparallel reconnection. We find that the inertialess reconstruction of its electron diffusion region works reasonably well only when the spacecraft path passes close to the center of the reconnection site where the magnetic field is zero and the electron flow has a stagnation point. When the path is located farther away, the effects of electron inertia, and probably also deviations from the Hesse formula, cause the quality of the reconstruction to deteriorate. Electron inertia is included in the theoretical development presented here but requires a more complicated numerical reconstruction code. The development and testing of such a code is underway and will be presented separately.

  5. Born to flip. Exit decisions of entrepreneurial firms in high-tech and low-tech industries

    NARCIS (Netherlands)

    E. Cefis (Elena); O. Marsili (Orietta)

    2011-01-01

    textabstractThis paper examines the way that the exit behavior of entrepreneurial firms is shaped by their innovative capabilities, and the technology environment in which they operate. We distinguish between exit by closing down activity and exit by merger or acquisition (M&A). Using a large sample

  6. The Role of Drosophila Merlin in the Control of Mitosis Exit and Development

    National Research Council Canada - National Science Library

    Chang, Long-Sheng

    2008-01-01

    To better understand the mechanism by which Merlin functions as a tumor suppressor, we have confirmed that Drosophila Merlin plays important roles in the control of mitosis exit and in the determination...

  7. NAD+ Is a Food Component That Promotes Exit from Dauer Diapause in Caenorhabditis elegans.

    Science.gov (United States)

    Mylenko, Mykola; Boland, Sebastian; Penkov, Sider; Sampaio, Julio L; Lombardot, Benoit; Vorkel, Daniela; Verbavatz, Jean-Marc; Kurzchalia, Teymuras V

    2016-01-01

    The free-living soil nematode Caenorhabditis elegans adapts its development to the availability of food. When food is scarce and population density is high, worms enter a developmentally arrested non-feeding diapause stage specialized for long-term survival called the dauer larva. When food becomes available, they exit from the dauer stage, resume growth and reproduction. It has been postulated that compound(s) present in food, referred to as the "food signal", promote exit from the dauer stage. In this study, we have identified NAD+ as a component of bacterial extract that promotes dauer exit. NAD+, when dissolved in alkaline medium, causes opening of the mouth and ingestion of food. We also show that to initiate exit from the dauer stage in response to NAD+ worms require production of serotonin. Thus, C. elegans can use redox cofactors produced by dietary organisms to sense food.

  8. Exit, Voice, and Loyalty in the Italian Public Health Service: Macroeconomic and Corporate Implications

    Directory of Open Access Journals (Sweden)

    Adelaide Ippolito

    2013-01-01

    Full Text Available The paper analyses how customers of public health organizations can express their dissatisfaction for the services offered to them. The main aim is to evaluate the effects that possible dissatisfaction of Italian public health service customers can have on public health organizations. We adopted the methodological scheme developed by Hirschman with exit, voice, and loyalty, considering the macroeconomic and corporate implications that it causes for Italian public health organizations. The study investigated the effects developed by exit of the patients on the system of financing of local health authorities considering both the corporate level of analysis and the macroeconomic level. As a result, local health authority management is encouraged to pay greater attention to the exit phenomena through the adoption of tools that promote loyalty, such as the promotion of voice, even if exit is not promoting, at a macroeconomic level, considerable attention to this phenomenon.

  9. Taking Exit Rights Seriously: Why Governance and Fee Litigation Don't Work in Mutual Funds

    National Research Council Canada - National Science Library

    JOHN MORLEY; QUINN CURTIS

    2010-01-01

    ...—they redeem them from the issuing funds for cash. We argue that this unique form of exit almost completely eliminates mutual fund investors' incentives to use voting, boards, and fee liability...

  10. Exit, voice, and loyalty in the Italian public health service: macroeconomic and corporate implications.

    Science.gov (United States)

    Ippolito, Adelaide; Impagliazzo, Cira; Zoccoli, Paola

    2013-01-01

    The paper analyses how customers of public health organizations can express their dissatisfaction for the services offered to them. The main aim is to evaluate the effects that possible dissatisfaction of Italian public health service customers can have on public health organizations. We adopted the methodological scheme developed by Hirschman with exit, voice, and loyalty, considering the macroeconomic and corporate implications that it causes for Italian public health organizations. The study investigated the effects developed by exit of the patients on the system of financing of local health authorities considering both the corporate level of analysis and the macroeconomic level. As a result, local health authority management is encouraged to pay greater attention to the exit phenomena through the adoption of tools that promote loyalty, such as the promotion of voice, even if exit is not promoting, at a macroeconomic level, considerable attention to this phenomenon.

  11. Immigration policy, foreign agricultural labor, and exit intentions in the United States dairy industry.

    Science.gov (United States)

    Susanto, D; Rosson, C P; Anderson, D P; Adcock, F J

    2010-04-01

    United States agriculture is dependent on foreign labor. Current US immigration policies have been alleged to disrupt agricultural labor availability, particularly that of hired foreign labor. A national survey of dairy farmers across herd sizes and regions of the United States was conducted and the results were used to estimate the extent to which hired foreign labor dependency will affect exit intentions in dairy farming. This study found that the expected probability of exit from dairy farming increased as the use of hired foreign labor intensified. But the expected probability of exit also decreased rapidly as herd sizes got larger. Given the immigration policy currently in place, farmers expecting labor shortages in the future are expected to experience greater tendency to exit the industry. Copyright (c) 2010 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.

  12. The effect of the introduction of an exit tube on the separation efficiency in a cyclone

    Directory of Open Access Journals (Sweden)

    J. Cernecky

    2013-09-01

    Full Text Available The paper shows the analysis of the effect of introduction of an exit tube into the cylindrical part of a cyclone on the flow velocity, pressure losses and, above all, the separation efficiency. We made measurements and carried out CFD simulations for three levels of the exit tube introduction. The ratios of the depth of the exit tube introduction to the cyclone diameter (Hp/D were 0.4, 0.475 and 0.89 at three velocity settings of 8 m.s-1, 13 m.s-1 and 15 m.s-1. The Reynolds Stress Model (RSM, which was compatible with the experimental results, was used for numerical solutions. The efficiency of cyclone separation was explored on a sample of oak sawdust. The efficiency of cyclone separation increased with the geometric size of the particles, the inlet velocity and a deeper introduction of the exit tube.

  13. Factors Associated with Female Online Sex Workers’ Intentions to Exit from Sex Work

    OpenAIRE

    Drucker, Jesse

    2016-01-01

    The sex work industry has evolved with the emergence of internet marketing, but little research examines sex workers who advertise online (i.e., online sex workers). This study is based on semi-structured interviews conducted in Southern California in 2014, with twenty-seven female online sex workers who provide mainstream sexual services to a male clientele. It focuses on sex workers’ perceptions of exit from sex work, and examines factors related to exit intentions, including relationships ...

  14. Assessing the impact of education and marriage on labor market exit decisions of women

    OpenAIRE

    Julie L. Hotchkiss; Pitts, M. Melinda; Walker, Mary Beth

    2010-01-01

    During the late 1990s, the convergence of women's labor force participation rates to men's rates came to a halt. This paper explores the degree to which the role of education and marriage in women's labor supply decisions also changed over this time period. Specifically, this paper investigates women's decisions to exit the labor market upon the birth of a child. The results indicate that changing exit behavior among married, educated women at this period in their lives was not likely the dri...

  15. Modeling acoustic wave propagation in isotropic medium

    Science.gov (United States)

    Krasnoveikin, V. A.; Druzhinin, N. V.; Derusova, D. A.; Tarasov, S. Yu.

    2017-12-01

    The paper carries out the graphical analysis of acoustic wave propagation in plates of different thickness to reveal the surface wave patterns formed on the plate surfaces. The results of the analysis allowed explaining the non-uniform distribution of the surface wave pattern nodes formed on the PMMA plate by a point oscillator. The wave pattern reconstruction made it possible to reveal fundamental and reflected waves as well as their interference patterns with node distributions on the surfaces of the plate. These results may be useful for defect detection in composite materials such as delamination, impact damage, gaps, etc.

  16. EXIT25 - Executive interview applied to a cognitively healthy elderly population with heterogeneous educational background

    Directory of Open Access Journals (Sweden)

    Maria Niures P.S. Matioli

    Full Text Available Abstract Education interferes with the performance in most cognitive tests, including executive function assessment. Objective: To investigate the effects of education on the performance of healthy elderly on the Brazilian version of the Executive Interview (EXIT25. Methods: The EXIT25 was administered to a sample of 83 healthy elderly. The subjects were also submitted to the Mini-Mental State Examination (MMSE, a delayed recall test, clock drawing and category fluency (animals/min tests in order to rule out cognitive impairment. The Geriatric Depression Scale (GDS was employed to exclude clinically-relevant depressive symptoms. The total sample was divided into three groups according to educational level: G1 (1-4 years, G2 (5-8 years and G3 (>8 years. Results: The mean values for age, educational level, MMSE and EXIT25 scores of all subjects were 72.2, 7.5, 27.6 and 6.9, respectively. The scores on the EXIT25 for each group were: G1=8.3, G2=5.9 and G3=5.8. There was a statistical difference between the performance of G1 and the other two groups on the EXIT25. Conclusions: The Brazilian version of the EXIT25 proved straightforward to administer. The performance of this sample of healthy elderly on the test was significantly influenced by educational level.

  17. Plasma waves

    CERN Document Server

    Swanson, DG

    1989-01-01

    Plasma Waves discusses the basic development and equations for the many aspects of plasma waves. The book is organized into two major parts, examining both linear and nonlinear plasma waves in the eight chapters it encompasses. After briefly discussing the properties and applications of plasma wave, the book goes on examining the wave types in a cold, magnetized plasma and the general forms of the dispersion relation that characterize the waves and label the various types of solutions. Chapters 3 and 4 analyze the acoustic phenomena through the fluid model of plasma and the kinetic effects. Th

  18. Neuromagnetic source reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, P.S.; Mosher, J.C. [Los Alamos National Lab., NM (United States); Leahy, R.M. [University of Southern California, Los Angeles, CA (United States)

    1994-12-31

    In neuromagnetic source reconstruction, a functional map of neural activity is constructed from noninvasive magnetoencephalographic (MEG) measurements. The overall reconstruction problem is under-determined, so some form of source modeling must be applied. We review the two main classes of reconstruction techniques-parametric current dipole models and nonparametric distributed source reconstructions. Current dipole reconstructions use a physically plausible source model, but are limited to cases in which the neural currents are expected to be highly sparse and localized. Distributed source reconstructions can be applied to a wider variety of cases, but must incorporate an implicit source, model in order to arrive at a single reconstruction. We examine distributed source reconstruction in a Bayesian framework to highlight the implicit nonphysical Gaussian assumptions of minimum norm based reconstruction algorithms. We conclude with a brief discussion of alternative non-Gaussian approachs.

  19. Wave-equation dispersion inversion

    KAUST Repository

    Li, Jing

    2016-12-08

    We present the theory for wave-equation inversion of dispersion curves, where the misfit function is the sum of the squared differences between the wavenumbers along the predicted and observed dispersion curves. The dispersion curves are obtained from Rayleigh waves recorded by vertical-component geophones. Similar to wave-equation traveltime tomography, the complicated surface wave arrivals in traces are skeletonized as simpler data, namely the picked dispersion curves in the phase-velocity and frequency domains. Solutions to the elastic wave equation and an iterative optimization method are then used to invert these curves for 2-D or 3-D S-wave velocity models. This procedure, denoted as wave-equation dispersion inversion (WD), does not require the assumption of a layered model and is significantly less prone to the cycle-skipping problems of full waveform inversion. The synthetic and field data examples demonstrate that WD can approximately reconstruct the S-wave velocity distributions in laterally heterogeneous media if the dispersion curves can be identified and picked. The WD method is easily extended to anisotropic data and the inversion of dispersion curves associated with Love waves.

  20. Assimilation of Wave Imaging Radar Observations for Real-time Wave-by-Wave Forecasting

    Energy Technology Data Exchange (ETDEWEB)

    Simpson, Alexandra [Oregon State Univ., Corvallis, OR (United States); Haller, Merrick [Oregon State Univ., Corvallis, OR (United States). School of Civil & Construction Engineering; Walker, David [SRI International, Menlo Park, CA (United States); Lynett, Pat [Univ. of Southern California, Los Angeles, CA (United States)

    2017-08-29

    This project addressed Topic 3: “Wave Measurement Instrumentation for Feed Forward Controls” under the FOA number DE-FOA-0000971. The overall goal of the program was to develop a phase-resolving wave forecasting technique for application to the active control of Wave Energy Conversion (WEC) devices. We have developed an approach that couples a wave imaging marine radar with a phase-resolving linear wave model for real-time wave field reconstruction and forward propagation of the wave field in space and time. The scope of the project was to develop and assess the performance of this novel forecasting system. Specific project goals were as follows: Develop and verify a fast, GPU-based (Graphical Processing Unit) wave propagation model suitable for phase-resolved computation of nearshore wave transformation over variable bathymetry; Compare the accuracy and speed of performance of the wave model against a deep water model in their ability to predict wave field transformation in the intermediate water depths (50 to 70 m) typical of planned WEC sites; Develop and implement a variational assimilation algorithm that can ingest wave imaging radar observations and estimate the time-varying wave conditions offshore of the domain of interest such that the observed wave field is best reconstructed throughout the domain and then use this to produce model forecasts for a given WEC location; Collect wave-resolving marine radar data, along with relevant in situ wave data, at a suitable wave energy test site, apply the algorithm to the field data, assess performance, and identify any necessary improvements; and Develop a production cost estimate that addresses the affordability of the wave forecasting technology and include in the Final Report. The developed forecasting algorithm (“Wavecast”) was evaluated for both speed and accuracy against a substantial synthetic dataset. Early in the project, performance tests definitively demonstrated that the system was capable of

  1. Ex utero intrapartum treatment (EXIT) in the management of cervical lymphatic malformation.

    Science.gov (United States)

    Laje, Pablo; Peranteau, William H; Hedrick, Holly L; Flake, Alan W; Johnson, Mark P; Moldenhauer, Julie S; Adzick, N Scott

    2015-02-01

    The purpose of this study was to review the outcomes and technical details of EXIT procedures performed in fetuses with large cervical lymphatic malformations. A retrospective chart review of fetuses with a prenatal diagnosis of cervical lymphatic malformation evaluated at our center between 1995 and 2013 was performed. We evaluated a total of 112 fetuses with a prenatal diagnosis of cervical lymphatic malformation. Thirteen of the 112 fetuses (11%) were delivered by an EXIT procedure. Criteria to deliver by EXIT were: 1) deviation/compression/obstruction of the airway, and 2) involvement of the floor of the mouth. Two fetuses developed hydrops. Five fetuses developed polyhydramnios. Eleven EXITs were performed electively at term (n=7; 37-38 weeks) or late pre-term (n=4; 34-36/6 weeks), whereas two patients underwent emergency EXIT at 33 and 38 weeks, respectively. The airway was accessed successfully in 12 of 13 cases. Laryngoscopy only was sufficient in 7, rigid bronchoscopy was required in 4, and 1 required a tracheostomy. In one case with a massive lymphatic malformation of the face, neck, and airway, a tracheostomy was not attempted, and the fetus expired. Four patients had invasion of the larynx by the lymphatic malformation. Five patients required a tracheostomy later. Median time from fetal exposure to intubation was 8 (2-29) min. Median total EXIT time was 105.5 (67-142) min. Median maternal blood loss was 800 (300-1000) ml. Median maternal hospital stay was 4 (3-6) days. The EXIT procedure allows controlled airway access in fetuses with cervical lymphatic malformations and evidence of airway impairment on prenatal images. Copyright © 2015 Elsevier Inc. All rights reserved.

  2. Wave Star

    DEFF Research Database (Denmark)

    Kramer, Morten; Brorsen, Michael; Frigaard, Peter

    Denne rapport beskriver numeriske beregninger af forskellige flydergeometrier for bølgeenergianlæget Wave Star.......Denne rapport beskriver numeriske beregninger af forskellige flydergeometrier for bølgeenergianlæget Wave Star....

  3. Heat Waves

    Science.gov (United States)

    Heat Waves Dangers we face during periods of very high temperatures include: Heat cramps: These are muscular pains and ... having trouble with the heat. If a heat wave is predicted or happening… - Slow down. Avoid strenuous ...

  4. Wave Dragon

    DEFF Research Database (Denmark)

    Kofoed, Jens Peter; Frigaard, Peter; Sørensen, H. C.

    1998-01-01

    This paper concerns with the development of the wave energy converter (WEC) Wave Dragon. This WEC is based on the overtopping principle. An overview of the performed research done concerning the Wave Dragon over the past years is given, and the results of one of the more comprehensive studies......, concerning a hydraulic evaluation and optimisation of the geometry of the Wave Dragon, is presented. Furthermore, the plans for the future development projects are sketched....

  5. Gravitational Waves

    Energy Technology Data Exchange (ETDEWEB)

    Miller, Jonah Maxwell [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-10-18

    This report has slides on Gravitational Waves; Pound and Rebka: A Shocking Fact; Light is a Ruler; Gravity is the Curvature of Spacetime; Gravitational Waves Made Simple; How a Gravitational Wave Affects Stuff Here; LIGO; This Detection: Neutron Stars; What the Gravitational Wave Looks Like; The Sound of Merging Neutron Stars; Neutron Star Mergers: More than GWs; The Radioactive Cloud; The Kilonova; and finally Summary, Multimessenger Astronomy.

  6. Electromagnetic Waves

    OpenAIRE

    Blok, H.; van den Berg, P.M.

    2011-01-01

    This book is dedicated to various aspects of electromagnetic wave theory and its applications in science and technology. The covered topics include the fundamental physics of electromagnetic waves, theory of electromagnetic wave propagation and scattering, methods of computational analysis, material characterization, electromagnetic properties of plasma, analysis and applications of periodic structures and waveguide components, etc.

  7. Wave Dragon

    DEFF Research Database (Denmark)

    Tedd, James; Kofoed, Jens Peter; Knapp, W.

    2006-01-01

    Wave Dragon is a floating wave energy converter working by extracting energy principally by means of overtopping of waves into a reservoir. A 1:4.5 scale prototype has been sea tested for 20 months. This paper presents results from testing, experiences gained and developments made during...

  8. Wave phenomena

    CERN Document Server

    Towne, Dudley H

    1988-01-01

    This excellent undergraduate-level text emphasizes optics and acoustics, covering inductive derivation of the equation for transverse waves on a string, acoustic plane waves, boundary-value problems, polarization, three-dimensional waves and more. With numerous problems (solutions for about half). ""The material is superbly chosen and brilliantly written"" - Physics Today. Problems. Appendices.

  9. Symmetry associated with symmetry break: Revisiting ants and humans escaping from multiple-exit rooms

    Science.gov (United States)

    Ji, Q.; Xin, C.; Tang, S. X.; Huang, J. P.

    2018-02-01

    Crowd panic has incurred massive injuries or deaths throughout the world, and thus understanding it is particularly important. It is now a common knowledge that crowd panic induces "symmetry break" in which some exits are jammed while others are underutilized. Amazingly, here we show, by experiment, simulation and theory, that a class of symmetry patterns come to appear for ants and humans escaping from multiple-exit rooms while the symmetry break exists. Our symmetry pattern is described by the fact that the ratio between the ensemble-averaging numbers of ants or humans escaping from different exits is equal to the ratio between the widths of the exits. The mechanism lies in the effect of heterogeneous preferences of agents with limited information for achieving the Nash equilibrium. This work offers new insights into how to improve public safety because large public areas are always equipped with multiple exits, and it also brings an ensemble-averaging method for seeking symmetry associated with symmetry breaking.

  10. Effects of the geometric orientations of the nozzle exit on the breakup of free liquid jet

    Energy Technology Data Exchange (ETDEWEB)

    Lad, V. N.; Murthy, Z. V. P. [Sardar Vallabhbhai National Institute of Technology, Gujarat (India)

    2016-04-15

    Free liquid jets are produced through various geometric orientations of the nozzle exit. The breakup lengths of liquid jets under various geometric orientations of the nozzle exit were studied. Images of jets were captured using a high-speed camera with a maximum frame rate of 1000 frames per second and were analyzed to determine the dynamics between jets and breakup lengths. The breakup length of jets changes with the cut angle of the nozzle exit. In addition, adding polymer reduces the effect of the cut angle of the nozzle exit on the breakup length for an entire range of velocities. The effect of the cut angle on breakup length is predominant for aqueous solutions with surfactants. This work provides motivation for further computational research to study jet dynamics in a partially covered nozzle exit, such as the case in which the boundary conditions near the nozzle opening is more complex with the cut angle and its vertex position, which directly reflects liquid jet dynamics.

  11. Predicting The Exit Time Of Employees In An Organization Using Statistical Model

    Directory of Open Access Journals (Sweden)

    Ahmed Al Kuwaiti

    2015-08-01

    Full Text Available Employees are considered as an asset to any organization and each organization provide a better and flexible working environment to retain its best and resourceful workforce. As such continuous efforts are being taken to avoid or extend the exitwithdrawal of employees from the organization. Human resource managers are facing a challenge to predict the exit time of employees and there is no precise model existing at present in the literature. This study has been conducted to predict the probability of exit of an employee in an organization using appropriate statistical model. Accordingly authors designed a model using Additive Weibull distribution to predict the expected exit time of employee in an organization. In addition a Shock model approach is also executed to check how well the Additive Weibull distribution suits in an organization. The analytical results showed that when the inter-arrival time increases the expected time for the employees to exit also increases. This study concluded that Additive Weibull distribution can be considered as an alternative in the place of Shock model approach to predict the exit time of employee in an organization.

  12. Breast reconstruction - natural tissue

    Science.gov (United States)

    ... muscle flap; TRAM; Latissimus muscle flap with a breast implant; DIEP flap; DIEAP flap; Gluteal free flap; Transverse upper gracilis flap; TUG; Mastectomy - breast reconstruction with natural tissue; Breast cancer - breast reconstruction ...

  13. Head and face reconstruction

    Science.gov (United States)

    ... medlineplus.gov/ency/article/002980.htm Head and face reconstruction To use the sharing features on this page, please enable JavaScript. Head and face reconstruction is surgery to repair or reshape deformities ...

  14. Scramjet test flow reconstruction for a large-scale expansion tube, Part 1: quasi-one-dimensional modelling

    Science.gov (United States)

    Gildfind, D. E.; Jacobs, P. A.; Morgan, R. G.; Chan, W. Y. K.; Gollan, R. J.

    2017-11-01

    Large-scale free-piston driven expansion tubes have uniquely high total pressure capabilities which make them an important resource for development of access-to-space scramjet engine technology. However, many aspects of their operation are complex, and their test flows are fundamentally unsteady and difficult to measure. While computational fluid dynamics methods provide an important tool for quantifying these flows, these calculations become very expensive with increasing facility size and therefore have to be carefully constructed to ensure sufficient accuracy is achieved within feasible computational times. This study examines modelling strategies for a Mach 10 scramjet test condition developed for The University of Queensland's X3 facility. The present paper outlines the challenges associated with test flow reconstruction, describes the experimental set-up for the X3 experiments, and then details the development of an experimentally tuned quasi-one-dimensional CFD model of the full facility. The 1-D model, which accurately captures longitudinal wave processes, is used to calculate the transient flow history in the shock tube. This becomes the inflow to a higher-fidelity 2-D axisymmetric simulation of the downstream facility, detailed in the Part 2 companion paper, leading to a validated, fully defined nozzle exit test flow.

  15. Wave theory of information

    CERN Document Server

    Franceschetti, Massimo

    2017-01-01

    Understand the relationship between information theory and the physics of wave propagation with this expert guide. Balancing fundamental theory with engineering applications, it describes the mechanism and limits for the representation and communication of information using electromagnetic waves. Information-theoretic laws relating functional approximation and quantum uncertainty principles to entropy, capacity, mutual information, rate distortion, and degrees of freedom of band-limited radiation are derived and explained. Both stochastic and deterministic approaches are explored, and applications for sensing and signal reconstruction, wireless communication, and networks of multiple transmitters and receivers are reviewed. With end-of-chapter exercises and suggestions for further reading enabling in-depth understanding of key concepts, it is the ideal resource for researchers and graduate students in electrical engineering, physics and applied mathematics looking for a fresh perspective on classical informat...

  16. Hedgehog signaling acts with the temporal cascade to promote neuroblast cell cycle exit.

    Directory of Open Access Journals (Sweden)

    Phing Chian Chai

    Full Text Available In Drosophila postembryonic neuroblasts, transition in gene expression programs of a cascade of transcription factors (also known as the temporal series acts together with the asymmetric division machinery to generate diverse neurons with distinct identities and regulate the end of neuroblast proliferation. However, the underlying mechanism of how this "temporal series" acts during development remains unclear. Here, we show that Hh signaling in the postembryonic brain is temporally regulated; excess (earlier onset of Hh signaling causes premature neuroblast cell cycle exit and under-proliferation, whereas loss of Hh signaling causes delayed cell cycle exit and excess proliferation. Moreover, the Hh pathway functions downstream of Castor but upstream of Grainyhead, two components of the temporal series, to schedule neuroblast cell cycle exit. Interestingly, hh is likely a target of Castor. Hence, Hh signaling provides a link between the temporal series and the asymmetric division machinery in scheduling the end of neurogenesis.

  17. Research on water-exit and take-off process for Morphing Unmanned Submersible Aerial Vehicle

    Science.gov (United States)

    Hu, Jun-hua; Xu, Bao-wei; Feng, Jin-fu; Qi, Duo; Yang, Jian; Wang, Cong

    2017-04-01

    This paper presents a theoretic implementation method of Morphing Unmanned Submersible Aerial Vehicle (MUSAV), which can both submerge in the water and fly in the air. Two different shapes are put forward so that the vehicle can suit both submergence and flight, considering the tremendous differences between hydrodynamic configuration and aerodynamic configuration of a vehicle. The transition of the two shapes can be achieved by using morphing technology. The water-to-air process, including water-exit, morphing, take-off and steady flight, is analyzed. The hydrodynamic and aerodynamic model of the vehicle exiting the water surface obliquely and then taking off into the air has been founded. The control strategy after morphing is analyzed and the control method is given. Numerical method is used to validate the motion model of the water-exit process. Results of simulations show the validity of the proposed model and the feasibility of MUSAV in theory.

  18. CC chemokine receptor 7 required for T lymphocyte exit from peripheral tissues

    Science.gov (United States)

    Debes, Gudrun F.; Arnold, Carrie N.; Young, Alan J.; Krautwald, Stefan; Lipp, Martin; Hay, John B.; Butcher, Eugene C.

    2006-01-01

    Lymphocytes travel throughout the body to carry out immune surveillance and participate in inflammatory reactions. Their path takes them from blood through tissues into lymph and back to blood. Molecules that control lymphocyte recruitment into extralymphoid tissues are well characterized, but exit is assumed to be random. Here, we showed that lymphocyte emigration from the skin was regulated and pertussis toxin-sensitive. CD4+ lymphocytes emigrated more efficiently than CD8+ or B lymphocytes. T lymphocytes in the afferent lymph expressed functional CCR7, and CCR7 was required for T lymphocyte exit from the skin. The regulated expression of CCR7 by tissue T lymphocytes may control their exit, acting with recruitment mechanisms to regulate lymphocyte transit and accumulation during immune surveillance and inflammation. PMID:16116468

  19. Demographic analysis of foreign visitors to the EXIT festival, Novi Sad

    Directory of Open Access Journals (Sweden)

    Bjeljac Željko

    2011-01-01

    Full Text Available In this paper we studied the habits and behaviour of visitors of EXIT tourist event in Novi Sad. The research was conducted on a sample of 189 randomly selected respondents from abroad. The aim was to determine whether there is a difference in the motives of foreign tourists coming to EXIT, a selection of vehicles, as well as the use of various means of tourist propaganda and the structure of expenditure of funds at foreign visitors. EXIT festival, Novi Sad has been selected for the survey because of growing brand of the festival in the total tourist offer of Serbia, specific groups of visitors, the number of foreign tourists, the links with the locality of maintaining.

  20. Ecologies of ideologies: Explaining party entry and exit in West-European parliaments, 1945-2013.

    Science.gov (United States)

    van de Wardt, Marc; Berkhout, Joost; Vermeulen, Floris

    2017-06-01

    This study introduces a population-ecological approach to the entry and exit of political parties. A primary proposition of population ecology is that organizational entry and exit depends on the number of organizations already present: that is, density. We propose that political parties mainly experience competition from parties in the same ideological niche (left, centre, right). Pooled time-series analyses of 410 parties, 263 elections and 18 West-European countries largely support our expectations. We find that political parties are more likely to exit when density within their niche increases. Also there is competition between adjacent ideological niches, i.e. between centrist and right-wing niches. In contrast to our expectations, neither density nor institutional rules impact party entry. This raises important questions about the rationale of prospective entrants.

  1. Exit Polling in an Emergent Democracy: The Complex Case of Ukraine

    Directory of Open Access Journals (Sweden)

    Natalya Nikolaevna Kharchenko

    2010-05-01

    Full Text Available This report considers the methodological specifics of conducting exit polls to verify election returns, mainly using an example of election campaigns in Ukraine from 2002-2007. The deepest public resonance was aroused by exit polls conducted after the second round of Ukrainian presidential elections in 2004. These polls were one of the factors, which led to massive demonstrations (the so-called "Orange Revolution" and the revocation of election results. The authors show that in the environment of administrative pressure on voters, governmental control of mass media, and severe political struggle, inaccuracy increases. Thus, to acquire reliable and valid information, the polling methods used must be modified. The recommendations given for the methodology of conducting exit polls may be useful for emergent democratic countries.

  2. Prediction of midline dose from entrance ad exit dose using OSLD measurements for total irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Chang Heon; Park, Jong Min; Park, So Yeon; Chun, Min Soo; Han, Ji Hye; Cho, Jin Dong; Kim, Jung In [Dept. of Radiation Oncology, Seoul National University Hospital, Seoul (Korea, Republic of)

    2017-06-15

    This study aims to predict the midline dose based on the entrance and exit doses from optically stimulated luminescence detector (OSLD) measurements for total body irradiation (TBI). For TBI treatment, beam data sets were measured for 6 MV and 15 MV beams. To evaluate the tissue lateral effect of various thicknesses, the midline dose and peak dose were measured using a solid water phantom (SWP) and ion chamber. The entrance and exit doses were measured using OSLDs. OSLDs were attached onto the central beam axis at the entrance and exit surfaces of the phantom. The predicted midline dose was evaluated as the sum of the entrance and exit doses by OSLD measurement. The ratio of the entrance dose to the exit dose was evaluated at various thicknesses. The ratio of the peak dose to the midline dose was 1.12 for a 30 cm thick SWP at both energies. When the patient thickness is greater than 30 cm, the 15 MV should be used to ensure dose homogeneity. The ratio of the entrance dose to the exit dose was less than 1.0 for thicknesses of less than 30 cm and 40 cm at 6 MV and 15 MV, respectively. Therefore, the predicted midline dose can be underestimated for thinner body. At 15 MV, the ratios were approximately 1.06 for a thickness of 50 cm. In cases where adult patients are treated with the 15 MV photon beam, it is possible for the predicted midline dose to be overestimated for parts of the body with a thickness of 50 cm or greater. The predicted midline dose and OSLD-measured midline dose depend on the phantom thickness. For in-vivo dosimetry of TBI, the measurement dose should be corrected in order to accurately predict the midline dose.

  3. The use of an electronic portal imaging device for exit dosimetry and quality control measurements.

    Science.gov (United States)

    Kirby, M C; Williams, P C

    1995-02-01

    To determine ways in which electronic portal imaging devices (EPIDs) could be used to (a) measure exit doses for external beam radiotherapy and (b) perform quality control checks on linear accelerators. When imaging, our fluoroscopic EPID adjusts the gain, offset, and frame acquisition time of the charge coupled device (CCD) camera automatically, to allow for the range of photon transmissions through the patient, and to optimize the signal-to-noise ratio. However, our EPID can be programmed to act as an integrating dosemeter. EPID dosemeter measurements were made for 20 MV photons, for different field sizes and thicknesses of unit density phantom material placed at varying exit surface to detector distances. These were compared with simultaneous Silicon diode exit dose measurements. Our exit dosimetry technique was verified using an anthropomorphic type phantom, and some initial measurements have been made for patients treated with irregularly shaped 20 MV x-ray fields. In this dosimetry mode, our EPID was also used to measure certain quality control parameters, x-ray field flatness, and the verification of segmented intensity modulated field prescriptions. Configured for dosimetry, our EPID exhibited a highly linear response, capable of resolving individual monitor units. Exit doses could be measured to within about 3% of that measured using Silicon diodes. Field flatness was determined to within 1.5% of Farmer dosemeter measurements. Segmented intensity modulated fields can be easily verified. Our EPID has the versatility to assess a range of parameters pertinent to the delivery of high quality, high precision radiotherapy. When configured appropriately, it can measure exit doses in vivo, with reasonable accuracy, perform certain quick quality control checks, and analyze segmented intensity modulated treatment fields.

  4. The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.

    Science.gov (United States)

    Bandura, Jennifer L; Jiang, Huaqi; Nickerson, Derek W; Edgar, Bruce A

    2013-01-01

    The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription factor and Cyclin/Cdk kinases. However, the full complement of mechanisms necessary to restrain E2F/DP and Cyclin/Cdk activities in differentiating cells are not known. Here, we have performed a genetic screen in Drosophila melanogaster, designed to identify genes required for cell cycle exit. This screen utilized a PCNA-miniwhite(+) reporter that is highly E2F-responsive and results in a darker red eye color when crossed into genetic backgrounds that delay cell cycle exit. Mutation of Hsp83, the Drosophila homolog of mammalian Hsp90, results in increased E2F-dependent transcription and ectopic cell proliferation in pupal tissues at a time when neighboring wild-type cells are postmitotic. Further, these Hsp83 mutant cells have increased Cyclin/Cdk activity and accumulate proteins normally targeted for proteolysis by the anaphase-promoting complex/cyclosome (APC/C), suggesting that APC/C function is inhibited. Indeed, reducing the gene dosage of an inhibitor of Cdh1/Fzr, an activating subunit of the APC/C that is required for timely cell cycle exit, can genetically suppress the Hsp83 cell cycle exit phenotype. Based on these data, we propose that Cdh1/Fzr is a client protein of Hsp83. Our results reveal that Hsp83 plays a heretofore unappreciated role in promoting APC/C function during cell cycle exit and suggest a mechanism by which Hsp90 inhibition could promote genomic instability and carcinogenesis.

  5. The molecular chaperone Hsp90 is required for cell cycle exit in Drosophila melanogaster.

    Directory of Open Access Journals (Sweden)

    Jennifer L Bandura

    Full Text Available The coordination of cell proliferation and differentiation is crucial for proper development. In particular, robust mechanisms exist to ensure that cells permanently exit the cell cycle upon terminal differentiation, and these include restraining the activities of both the E2F/DP transcription factor and Cyclin/Cdk kinases. However, the full complement of mechanisms necessary to restrain E2F/DP and Cyclin/Cdk activities in differentiating cells are not known. Here, we have performed a genetic screen in Drosophila melanogaster, designed to identify genes required for cell cycle exit. This screen utilized a PCNA-miniwhite(+ reporter that is highly E2F-responsive and results in a darker red eye color when crossed into genetic backgrounds that delay cell cycle exit. Mutation of Hsp83, the Drosophila homolog of mammalian Hsp90, results in increased E2F-dependent transcription and ectopic cell proliferation in pupal tissues at a time when neighboring wild-type cells are postmitotic. Further, these Hsp83 mutant cells have increased Cyclin/Cdk activity and accumulate proteins normally targeted for proteolysis by the anaphase-promoting complex/cyclosome (APC/C, suggesting that APC/C function is inhibited. Indeed, reducing the gene dosage of an inhibitor of Cdh1/Fzr, an activating subunit of the APC/C that is required for timely cell cycle exit, can genetically suppress the Hsp83 cell cycle exit phenotype. Based on these data, we propose that Cdh1/Fzr is a client protein of Hsp83. Our results reveal that Hsp83 plays a heretofore unappreciated role in promoting APC/C function during cell cycle exit and suggest a mechanism by which Hsp90 inhibition could promote genomic instability and carcinogenesis.

  6. Molecular signature of cell cycle exit induced in human T lymphoblasts by IL-2 withdrawal

    Directory of Open Access Journals (Sweden)

    Pfeifer Aleksandra

    2009-06-01

    Full Text Available Abstract Background The molecular mechanisms of cell cycle exit are poorly understood. Studies on lymphocytes at cell cycle exit after growth factor deprivation have predominantly focused on the initiation of apoptosis. We aimed to study gene expression profile of primary and immortalised IL-2-dependent human T cells forced to exit the cell cycle by growth factor withdrawal, before apoptosis could be evidenced. Results By the Affymetrix microarrays HG-U133 2.0 Plus, 53 genes were distinguished as differentially expressed before and soon after IL-2 deprivation. Among those, PIM1, BCL2, IL-8, HBEGF, DUSP6, OSM, CISH, SOCS2, SOCS3, LIF and IL13 were down-regulated and RPS24, SQSTM1, TMEM1, LRRC8D, ECOP, YY1AP1, C1orf63, ASAH1, SLC25A46 and MIA3 were up-regulated. Genes linked to transcription, cell cycle, cell growth, proliferation and differentiation, cell adhesion, and immune functions were found to be overrepresented within the set of the differentially expressed genes. Conclusion Cell cycle exit of the growth factor-deprived T lymphocytes is characterised by a signature of differentially expressed genes. A coordinate repression of a set of genes known to be induced during T cell activation is observed. However, growth arrest following exit from the cell cycle is actively controlled by several up-regulated genes that enforce the non-dividing state. The identification of genes involved in cell cycle exit and quiescence provides new hints for further studies on the molecular mechanisms regulating the non-dividing state of a cell, the mechanisms closely related to cancer development and to many biological processes.

  7. Massive facial teratoma managed with the ex utero intrapartum treatment (EXIT procedure and use of a 3-dimensional printed model for planning of staged debulking

    Directory of Open Access Journals (Sweden)

    Maggie M. Hodges

    2017-02-01

    Full Text Available Teratomas are the most frequent solid tumor found in neonates. However, only 1.5% of neonatal teratomas originate from facial structures. Neonatal facial teratomas are associated with polyhydramnios, preterm birth, pulmonary hypoplasia, cleft palate, cleft lip, and life-threatening airway compromise. The overall survival reported with these lesions has been between 17 and 87.5%; however survival in the setting of antenatally diagnosed facial teratomas has only been described anecdotally. We present a case of an antenatally diagnosed massive facial teratoma originating from the pterygomaxillary fossa, which was associated with polyhydramnios and pre-term birth. We managed this complex tumor with an ex utero intrapartum treatment (EXIT procedure, multidisciplinary medical and surgical team, and staged excision and reconstruction aided by use of a 3-dimensional printed model. Here we review the surgical management of this rare and complex tumor.

  8. Where no wave has gone before: unconventional elastic wave fields in exotic regimes

    Science.gov (United States)

    Bohlen, T.

    2012-04-01

    Nowadays, elastic wave fields are acquired on land, at the sea or or within tunnels and boreholes. The increasing availability of computational resources allow to use their full information content, e.g., P- and S-waves, converted waves, guided and interface waves, to image geological discontinuities and/or to reconstruct multi-parameter models. For the full consideration of elastic wave propagation effects the efficient forward simulation in 3-D complex media gains in importance. Full wave field modelling is essential for seismic imaging and inversion but also to invent and verify new seismic reconstruction techniques. Innovative seismic methods sometimes use unconventional elastic wave fields having very specific properties and being the only solution for some exotic applications. Such unconventional elastic wave fields, for example, are exploited for the seismic prediction ahead of tunnels. Tunnel surface-waves that arrive at the front face of the tunnel are converted into body-waves. Reflected body-waves are later back-converted into tunnel surface-waves. Imaging methods based on these wave fields can successfully detect geological discontinuities ahead. The conversion of interface waves and body waves can also be observed in fluid-filled boreholes and can be used for seismic prediction while drilling. Other unconventional waves in an exotic regime are marine Scholte waves that can be excited by airguns. Scholte waves are interface waves propagating along the sea floor and can be used to reconstruct the shear-wave velocity of shallow water marine sediments - an important parameter to characterize the stability of the marine sediments for offshore constructions. The ultimative goal, however, is the consistent consideration of both unconven¬tional waves as well as all other possible elastic wave propagation effects by full waveform inversion (FWI). Over the last several years, computer resources have brought 3D elastic FWI computations within reach. Some early

  9. Plasma arc welding torch having means for vortexing plasma gas exiting the welding torch

    Science.gov (United States)

    Rybicki, Daniel J. (Inventor); Mcgee, William F. (Inventor)

    1994-01-01

    A plasma arc welding torch is described wherein a plasma gas is directed through the body of the welding torch and out of the body across the tip of the welding electrode disposed at the forward end of the body. The plasma gas is provided with a vortexing motion prior to exiting the body by a vortex motion imparting member which is mounted in an orifice housing member and carried in the forward portion of the torch body. The orifice housing member is provided with an orifice of an predetermined diameter through which the electric arc and the plasma gas exits.

  10. Fast Water Transport in CNTs: length dependence and entrane/exit effects

    DEFF Research Database (Denmark)

    Walther, Jens Honore; Koumoutsakos, Petros

    , for the first time, that under imposed pressures of the order of 1 bar, water entry into the CNT cavity and exit from the CNT end, can occur only on pre-wetted membranes. We conduct large scale simulations for up to 500nm long CNTs and observe a previously unseen dependence of the flow enhancement rates......Superfast water transport in carbon nanotube (CNT) membranes has been reported in experimental studies. We use Molecular Dynamics simulations to elucidate the mechanisms of water entry, exit and transport in 2nm-diameter hydrophobic CNTs embedded in a hydrophilic membrane matrix. We demonstrate...

  11. Efficiency, Leverage and Exit: The Role of Information Asymmetry in Concentrated Industries

    DEFF Research Database (Denmark)

    Siyahhan, Baran

    2011-01-01

    This paper develops a real options model of imperfect competition with asymmetric information that analyzes firms’ exit decisions. Optimal exit decision is linked to firm characteristics such as financial leverage and efficiency. The model shows that informational asymmetries can lead more...... efficient and less leveraged firms to leave the product market prematurely. It also demonstrates how firm efficiency can increase debt capacity relative to rival firms. The model also has implications for firm risk and asset returns. Specifically, the paper shows that, when there is information asymmetry...

  12. Efficiency, Leverage and Exit: The Role of Information Asymmetry in Concentrated Industries

    DEFF Research Database (Denmark)

    Siyahhan, Baran

    This paper develops a real options model of imperfect competition with asymmetric information that analyzes firms’ exit decisions. Optimal exit decision is linked to firm characteristics such as financial leverage and efficiency. The model shows that informational asymmetries can lead more...... efficient and less leveraged firms to leave the product market prematurely. It also demonstrates how firm efficiency can increase debt capacity relative to rival firms. The model also has implications for firm risk and asset returns. Specifically, the paper shows that, when there is information asymmetry...

  13. One-way wave propagation with amplitude based on pseudo-differential operators

    NARCIS (Netherlands)

    op 't Root, T.J.P.M.; Stolk, C.C.

    2010-01-01

    The one-way wave equation is widely used in seismic migration. Equipped with wave amplitudes, the migration can be provided with the reconstruction of the strength of reflectivity. We derive the one-way wave equation with geometrical amplitude by using a symmetric square root operator and a wave

  14. One-way wave propagation with amplitude based on pseudo-differential operators

    NARCIS (Netherlands)

    op 't Root, T.J.P.M.; Stolk, C.C.

    The one-way wave equation is widely used in seismic migration. Equipped with wave amplitudes, the migration can be provided with the reconstruction of the strength of reflectivity. We derive the one-way wave equation with geometrical amplitude by using a symmetric square root operator and a wave

  15. Selective reconstruction of space-time spectra

    Science.gov (United States)

    Voronin, E. N.

    1985-12-01

    The relationship between the active component of mutual resistance and radiation patterns of arbitrary receive-transmit antennas is simplified on the basis of the reciprocity theorem. The simplification does not violate the identity of the relationship, and has a useful application to the correction of the near-field holograms of arbitrary sources with the aim of the selective reconstruction of the space-time spectra of homogeneous or inhomogeneous waves. The version of the relationship obtained can also be extended to acoustic antennas. Numerical simulation results are presented concerning the reconstruction of the radiation pattern of a half-wave dipole on the basis of near-field sounding in a cylindrical shielded chamber.

  16. The relationship of lateral anatomic structures to exiting guide pins during femoral tunnel preparation utilizing an accessory medial portal.

    Science.gov (United States)

    Farrow, Lutul D; Parker, Richard D

    2010-06-01

    Anatomic reconstruction of the anterior cruciate ligament through an accessory medial portal has become increasingly popular. The purpose of this study is to describe the relationship of guide pin exit points to the lateral anatomic structures when preparing the anterior cruciate ligament femoral tunnel through an accessory medial portal. We utilized seven fresh frozen cadaveric knees. Utilizing an anteromedial approach, a guide wire was placed into the center of each bundle's footprint. Each guide wire was advanced through the lateral femoral cortex. The guide pins were passed at 90, 110, and 130 degrees of knee flexion. The distances from each guide pin to the closest relevant structures on the lateral side of the knee were measured. At 90 degrees the posterolateral bundle guide pin was closest to the lateral condyle articular cartilage (mean 5.4 +/- 2.2 mm) and gastrocnemius tendon (mean 5.7 +/- 2.1 mm). At 110 degrees the posterolateral bundle pin was closest to the gastrocnemius tendon (mean 4.5 +/- 3.4 mm). At 130 degrees the posterolateral bundle pin was closest to the gastrocnemius tendon (mean 7.2 +/- 5.5 mm) and lateral collateral ligament (mean 6.8 +/- 2.1 mm). At 90 degrees the anteromedial bundle guide pin was closest to the articular cartilage (mean 2.0 +/- 2.0 mm). At 110 degrees the anteromedial bundle pin was closest to the articular cartilage (mean 7.4 +/- 3.5 mm) and gastrocnemius tendon (mean 12.3 +/- 3.1 mm). At 130 degrees the AM bundle pin was closest to the gastrocnemius tendon (mean 8.2 +/- 3.2 mm) and LCL (mean 15.1 +/- 2.9 mm). Neither guide pin (anteromedial or posterolateral bundle) put the peroneal nerve at risk at any knee flexion angle. At low knee flexion angles the anteromedial and posterolateral bundle guide pins closely approximated multiple lateral structures when using an accessory medial arthroscopic portal. Utilizing higher flexion angles increases the margin of error when preparing both femoral tunnels. During preparation of

  17. Gravitation Waves

    CERN Multimedia

    CERN. Geneva

    2005-01-01

    We will present a brief introduction to the physics of gravitational waves and their properties. We will review potential astrophysical sources of gravitational waves, and the physics and astrophysics that can be learned from their study. We will survey the techniques and technologies for detecting gravitational waves for the first time, including bar detectors and broadband interferometers, and give a brief status report on the international search effort, with special emphasis on the LIGO detectors and search results.

  18. Quantitative thermoacoustic image reconstruction of conductivity profiles

    Science.gov (United States)

    Ogunlade, Olumide; Cox, Ben; Beard, Paul

    2012-02-01

    A numerical inversion scheme for recovering a map of the absolute conductivity from the absorbed power density map that is conventionally reconstructed in thermacoustic imaging is described. This offers the prospect of obtaining an image that is more closely related to the underlying tissue structure and physiology. The inversion scheme employs a full 3D full wave model of electromagnetic propagation in tissue which is iteratively fitted to the measured absorbed power density map using a simple recursive method. The reconstruction is demonstrated numerically using three examples of absorbers of varying geometries, tissue realistic complex permittivity values and noise. In these examples, the reconstruction is shown to rapidly converge to within good estimates of the true conductivity in less than 20 iterations.

  19. Janus Waves

    OpenAIRE

    Papazoglou, Dimitris G.; Fedorov, Vladimir Yu.; Tzortzakis, Stelios

    2016-01-01

    We show the existence of a family of waves that share a common interesting property affecting the way they propagate and focus. These waves are a superposition of twin waves, which are conjugate to each other under inversion of the propagation direction. In analogy to holography, these twin "real" and "virtual" waves are related respectively to the converging and the diverging part of the beam and can be clearly visualized in real space at two distinct foci under the action of a focusing lens...

  20. Reconstructing the dark sector interaction with LISA

    Science.gov (United States)

    Cai, Rong-Gen; Tamanini, Nicola; Yang, Tao

    2017-05-01

    We perform a forecast analysis of the ability of the LISA space-based interferometer to reconstruct the dark sector interaction using gravitational wave standard sirens at high redshift. We employ Gaussian process methods to reconstruct the distance-redshift relation in a model independent way. We adopt simulated catalogues of standard sirens given by merging massive black hole binaries visible by LISA, with an electromagnetic counterpart detectable by future telescopes. The catalogues are based on three different astrophysical scenarios for the evolution of massive black hole mergers based on the semi-analytic model of E. Barausse, Mon. Not. Roy. Astron. Soc. 423 (2012) 2533. We first use these standard siren datasets to assess the potential of LISA in reconstructing a possible interaction between vacuum dark energy and dark matter. Then we combine the LISA cosmological data with supernovae data simulated for the Dark Energy Survey. We consider two scenarios distinguished by the time duration of the LISA mission: 5 and 10 years. Using only LISA standard siren data, the dark sector interaction can be well reconstructed from redshift z~1 to z~3 (for a 5 years mission) and z~1 up to z~5 (for a 10 years mission), though the reconstruction is inefficient at lower redshift. When combined with the DES datasets, the interaction is well reconstructed in the whole redshift region from 0z~ to z~3 (5 yr) and z~0 to z~5 (10 yr), respectively. Massive black hole binary standard sirens can thus be used to constrain the dark sector interaction at redshift ranges not reachable by usual supernovae datasets which probe only the zlesssim 1.5 range. Gravitational wave standard sirens will not only constitute a complementary and alternative way, with respect to familiar electromagnetic observations, to probe the cosmic expansion, but will also provide new tests to constrain possible deviations from the standard ΛCDM dynamics, especially at high redshift.

  1. Practical algorithms for simulation and reconstruction of digital in-line holograms.

    Science.gov (United States)

    Latychevskaia, Tatiana; Fink, Hans-Werner

    2015-03-20

    Here we present practical methods for simulation and reconstruction of in-line digital holograms recorded with plane and spherical waves. The algorithms described here are applicable to holographic imaging of an object exhibiting absorption as well as phase-shifting properties. Optimal parameters, related to distances, sampling rate, and other factors for successful simulation and reconstruction of holograms are evaluated and criteria for the achievable resolution are worked out. Moreover, we show that the numerical procedures for the reconstruction of holograms recorded with plane and spherical waves are identical under certain conditions. Experimental examples of holograms and their reconstructions are also discussed.

  2. Ethnic variations in immigrant poverty exit and female employment: the missing link.

    Science.gov (United States)

    Kaida, Lisa

    2015-04-01

    Despite widespread interest in poverty among recent immigrants and female immigrant employment, research on the link between the two is limited. This study evaluates the effect of recently arrived immigrant women's employment on the exit from family poverty and considers the implications for ethnic differences in poverty exit. It uses the bivariate probit model and the Fairlie decomposition technique to analyze data from the Longitudinal Survey of Immigrants to Canada (LSIC), a nationally representative survey of immigrants arriving in Canada, 2000-2001. Results show that the employment of recently arrived immigrant women makes a notable contribution to lifting families out of poverty. Moreover, the wide ethnic variations in the probability of exit from poverty between European and non-European groups are partially explained by the lower employment rates among non-European women. The results suggest that the equal earner/female breadwinner model applies to low-income recent immigrant families in general, but the male breadwinner model explains the low probability of poverty exit among select non-European groups whose female employment rates are notably low.

  3. Rational Entrepreneurship in Local China: Exit Plus Voice for Preferential Tax Treatments

    NARCIS (Netherlands)

    Z. Zhu (Ze); G.W.J. Hendrikse (George); B. Krug (Barbara)

    2006-01-01

    textabstractBearing the legacy from central-planned system, the tax system in local China still lacks transparency and, in many cases, the liabilities of firms, especially those with extensive influences, are subject to negotiation despite the new tax-reform 1994. Applying Hirschman’s Exit-Voice

  4. A Study of Vortex Rings from Cylinders with Inclined Exits Using V3V

    Science.gov (United States)

    Troolin, Daniel; Longmire, Ellen

    2008-11-01

    Volumetric 3-component velocimetry (V3V) was used to examine the vortical structures generated by impulsively driven pistons within surrounding cylinders. The piston stroke length L was equal to the cylinder inner diameter of 72.8 mm. The Reynolds number based on piston velocity and L was 2500. The measurement volume was 140mm x 140mm x 100mm, and the spatial resolution was 4mm. While an axisymmetric cylindrical exit yields a primary ring that is largely decoupled from a trailing ring of opposite circulation, inclined exits yield a much more complicated topology. The primary ring exits the cylinder with an initial inclination of approximately half the cylinder exit angle. Then, the primary ring interacts directly with two trailing rings associated with the piston stopping. The downstream portions of the trailing vortices are drawn in through the center of the primary vortex and subsequently stretched as they wind around the core of the primary ring. The upstream portions of the trailing rings intertwine. These interactions lead to earlier breakdown of the primary ring as well as decreases in propagation speed. Movies showing the detailed evolution of these structures will be shown.

  5. Voice, exit and efficacy : Dealing with perceived neighbourhood decline without moving out

    NARCIS (Netherlands)

    Van der Land, M.; Doff, W.

    Residents of deprived urban neighbourhoods with a changing population often experience an increase in insecurity. If they judge the change as decline, they are likely to become less satisfied with their residential situation and exhibit coping tactics. This paper combines Hirschman’s Exit, Voice and

  6. "Now My Old Self Is Thin": Stigma Exits after Weight Loss

    Science.gov (United States)

    Granberg, Ellen M.

    2011-01-01

    In this article, I employ a structural symbolic interaction framework to examine the processes by which persons can exit a stigmatized identity. Using the empirical example of weight loss, I analyze how individuals evolve from an identity as "fat" and stigmatized to one that is "normal" with respect to weight and free from identification with…

  7. 76 FR 23830 - Removing Designated Countries From the National Security Entry-Exit Registration System (NSEERS)

    Science.gov (United States)

    2011-04-28

    ... means to verify the entry and exit of aliens into and out of the United States. Improved intelligence... intelligence, DHS has refined its approach to identifying aliens posing a threat to the nation and applied... focusing on more general designations of groups of individuals, such as country of origin. DHS has...

  8. Why Do Some Employees Fall into and Fail to Exit a Job-Lock Situation?

    Directory of Open Access Journals (Sweden)

    Anna Huysse-Gaytandjieva

    2013-01-01

    Full Text Available Previous studies have paid little attention to the employees’ ability to exit a job-lock situation and factors that determine this ability. It remains unclear why some employees who experience job lock are able to exit this state while others remain in job lock. We use longitudinal data to identify employees who have fallen in the state of job lock and their subsequent behavior—exiting or remaining in job lock. By use of a first-order Markov transition models, we analyze the relevance of sociodemographic features, employment, occupational, sectoral, and contextual factors, as well as personality characteristics in explaining the transition or its absence. Overall the results show that both demographic factors and work-related aspects increase the likelihood that an employee enters the long-term job lock state (especially for older, married, full-time employed, those in a craft occupation and governmental sector, and in a region with high unemployment. Mental health problems and personality characteristics (low peak-end self-esteem and decisional procrastination have a significant effect on the probability to stay in long-term job lock. On the contrary, having a managerial, service, or associate occupation, working in the private sector, and having promotion opportunities increase the chance of an exit from the state of job lock.

  9. Using Exit Charts to Develop an Early Stopping Criterion for Turbo Decoding

    NARCIS (Netherlands)

    Potman, J.; Hoeksema, F.W.; Slump, Cornelis H.

    2004-01-01

    Early stopping criteria are used to determine when additional decoder iterations result in little or no improvement in the bit- error-rate (BER) at the output of a Turbo decoder. This paper proposes a stopping criterion based on Extrinsic Information Transfer (EXIT) charts. The generation and

  10. 49 CFR 571.217 - Standard No. 217; Bus emergency exits and window retention and release.

    Science.gov (United States)

    2010-10-01

    ... interior, to occupants having corrected visual acuity of 20/40 (Snellen ratio) seated in the adjacent seat... “Emergency Exit,” as appropriate, in letters at least 5 centimeters high, of a color that contrasts with its... instructions shall be in letters at least 1 centimeter high and of a color that contrasts with its background...

  11. Exploring Work and Development Options to Reduce Early Labour Force Exit of Mature Aged Australians

    Science.gov (United States)

    Pillay, Hitendra; Kelly, Kathy; Tones, Megan

    2008-01-01

    Early labour force exit is a significant challenge associated with the ageing workforce in Australia and many other developed countries. A reduction and increased flexibility of work hours has been suggested to improve labour force participation of the mature aged cohort. However, little is known about mature aged workers' aspirations for…

  12. Work Ability Index as Tool to Identify Workers at Risk of Premature Work Exit

    NARCIS (Netherlands)

    Roelen, Corne A. M.; Heymans, Martijn W.; Twisk, Jos W. R.; van der Klink, Jac J. L.; Groothoff, Johan W.; van Rhenen, Willem

    2014-01-01

    Purpose To investigate the Work Ability Index (WAI) as tool for identifying workers at risk of premature work exit in terms of disability pension, unemployment, or early retirement. Methods Prospective cohort study of 11,537 male construction workers (mean age 45.5 years), who completed the WAI at

  13. Voice, exit and efficacy : Dealing with perceived neighbourhood decline without moving out

    NARCIS (Netherlands)

    Van der Land, M.; Doff, W.

    2010-01-01

    Residents of deprived urban neighbourhoods with a changing population often experience an increase in insecurity. If they judge the change as decline, they are likely to become less satisfied with their residential situation and exhibit coping tactics. This paper combines Hirschman’s Exit, Voice and

  14. Groningen orthopaedic exit strategy : Validation of a support program after total hip or knee arthroplasty

    NARCIS (Netherlands)

    van den Akker-Scheek, Inge; Zijlstra, Wiebren; Groothoff, Johan W.; van Horn, Jim R.; Bulstra, Sjoerd K.; Stevens, Martin

    Objective: Validation of the program theory of the Groningen orthopaedic exit strategy (GOES), a theory-driven program aiming to improve the rehabilitation of total hip and knee arthroplasty patients after shortened hospital stay. First part of the program theory is the action theory, hypothesising

  15. Inhibition of the mitotic exit network in response to damaged telomeres.

    Directory of Open Access Journals (Sweden)

    Mauricio Valerio-Santiago

    Full Text Available When chromosomal DNA is damaged, progression through the cell cycle is halted to provide the cells with time to repair the genetic material before it is distributed between the mother and daughter cells. In Saccharomyces cerevisiae, this cell cycle arrest occurs at the G2/M transition. However, it is also necessary to restrain exit from mitosis by maintaining Bfa1-Bub2, the inhibitor of the Mitotic Exit Network (MEN, in an active state. While the role of Bfa1 and Bub2 in the inhibition of mitotic exit when the spindle is not properly aligned and the spindle position checkpoint is activated has been extensively studied, the mechanism by which these proteins prevent MEN function after DNA damage is still unclear. Here, we propose that the inhibition of the MEN is specifically required when telomeres are damaged but it is not necessary to face all types of chromosomal DNA damage, which is in agreement with previous data in mammals suggesting the existence of a putative telomere-specific DNA damage response that inhibits mitotic exit. Furthermore, we demonstrate that the mechanism of MEN inhibition when telomeres are damaged relies on the Rad53-dependent inhibition of Bfa1 phosphorylation by the Polo-like kinase Cdc5, establishing a new key role of this kinase in regulating cell cycle progression.

  16. Teaching with a Technological Twist: Exit Tickets via Twitter in Literacy Classrooms

    Science.gov (United States)

    Amaro-Jiménez, Carla; Hungerford-Kresser, Holly; Pole, Kathryn

    2016-01-01

    In this article, the authors describe, reflect, and analyze the implementation of a commonly used teaching strategy with a technological twist: exit tickets via Twitter. Longitudinal data collected over the course of three years demonstrated that using Twitter to reinvent a nondigital teaching practice ultimately demonstrated a better…

  17. The Effects of the Specialization of Private Equity Firms on their Exit Strategy

    DEFF Research Database (Denmark)

    Rigamonti, Damiana; Cefis, Elena; Meoli, Michele

    2016-01-01

    We investigate how industry and stage specialization of Private Equity (PE) firms affect the likelihood to exit investments by means of trade sales, Initial Public Offerings (IPOs), or Secondary Buyouts (SBOs). Our empirical analysis relies on competing risks models. Using a sample of 818 Leveraged...

  18. The relationship between substance use and exit security on psychiatric wards

    NARCIS (Netherlands)

    Simpson, A.; Bowers, L.; Allan, T.; Haglund, K.; Muir-Cochrane, E.; Nijman, H.L.I.; Merwe, M. van der

    2011-01-01

    Aim. In this paper we report on the rates of drug/alcohol use on acute psychiatric wards in relation to levels and intensity of exit security measures. Background. Many inpatient wards have become permanently locked, with staff concerned about the risk of patients leaving the ward and harming

  19. Quantifying groundwater dependency of riparian surface hydrologic features using the exit gradient

    Science.gov (United States)

    This study examines groundwater exit gradients as a way to quantify groundwater interactions with surface water. We calibrated high resolution groundwater models for the basin fill sediments in the lower Calapooia watershed, Oregon, using data collected between 1928--2000. The e...

  20. Exit and Failure of Credit Unions in Brazil: A Risk Analysis

    Directory of Open Access Journals (Sweden)

    Flávio Leonel de Carvalho

    2015-04-01

    Full Text Available This study aims to investigate the factors that affect the market exit of Brazilian singular credit unions from 1995 to 2009; it also identifies and lists the determinants of various types of market exits and analyzes whether profitability is a significant factor for credit union survival. This study was conducted with accounting data provided by the Central Bank of Brazil, which derives only from individual cooperatives, i.e. singular credit unions. Quarterly financial statements from these credit unions that were active from 1995 to the second quarter of 2009 were employed, totaling 71,325 observations for 1,929 credit unions. Based on survival and the model of competing risks (such as the Cox, Exponential, Weibull, Gompertz, and Competing Risk models, the results show that there is no statistical evidence to ensure a correlation between profitability and credit union survival. The results also suggest that the size of credit unions plays a key role in their survival and longevity and that their funding and investment management are related to their survival and risk of market exit. In conclusion, the results confirm the initial idea that the duality inherent to credit unions - cooperative principles versus economic efficiency - might influence the stability, survival, and longevity of these institutions. Such results may also imply that a credit union embracing the rationale of a private bank will become more estranged from its members, something which will hinder its future operations and increase the likelihood of its exit from the market.

  1. On a mean field game optimal control approach modeling fast exit scenarios in human crowds

    KAUST Repository

    Burger, Martin

    2013-12-01

    The understanding of fast exit and evacuation situations in crowd motion research has received a lot of scientific interest in the last decades. Security issues in larger facilities, like shopping malls, sports centers, or festivals necessitate a better understanding of the major driving forces in crowd dynamics. In this paper we present an optimal control approach modeling fast exit scenarios in pedestrian crowds. The model is formulated in the framework of mean field games and based on a parabolic optimal control problem. We consider the case of a large human crowd trying to exit a room as fast as possible. The motion of every pedestrian is determined by minimizing a cost functional, which depends on his/her position and velocity, the overall density of people, and the time to exit. This microscopic setup leads in a mean-field formulation to a nonlinear macroscopic optimal control problem, which raises challenging questions for the analysis and numerical simulations.We discuss different aspects of the mathematical modeling and illustrate them with various computational results. ©2013 IEEE.

  2. Changes in Student Attributions Due to the Implementation of Central Exit Exams

    Science.gov (United States)

    Oerke, Britta; Maag Merki, Katharina; Holmeier, Monika; Jager, Daniela J.

    2011-01-01

    The central aim of standardized exit exams is to motivate students and teachers to work harder on critical subject matters and thus increase student achievement. However, the effects of the implementation of central exams on student motivation have not been analyzed in a longitudinal section until now. In the present study, the consequences of…

  3. Calculation of midplane dose for total body irradiation from entrance and exit dose MOSFET measurements.

    Science.gov (United States)

    Satory, P R

    2012-03-01

    This work is the development of a MOSFET based surface in vivo dosimetry system for total body irradiation patients treated with bilateral extended SSD beams using PMMA missing tissue compensators adjacent to the patient. An empirical formula to calculate midplane dose from MOSFET measured entrance and exit doses has been derived. The dependency of surface dose on the air-gap between the spoiler and the surface was investigated by suspending a spoiler above a water phantom, and taking percentage depth dose measurements (PDD). Exit and entrances doses were measured with MOSFETs in conjunction with midplane doses measured with an ion chamber. The entrance and exit doses were combined using an exponential attenuation formula to give an estimate of midplane dose and were compared to the midplane ion chamber measurement for a range of phantom thicknesses. Having a maximum PDD at the surface simplifies the prediction of midplane dose, which is achieved by ensuring that the air gap between the compensator and the surface is less than 10 cm. The comparison of estimated midplane dose and measured midplane dose showed no dependence on phantom thickness and an average correction factor of 0.88 was found. If the missing tissue compensators are kept within 10 cm of the patient then MOSFET measurements of entrance and exit dose can predict the midplane dose for the patient.

  4. Dynamics of evanescent matter waves in negative-index media

    Science.gov (United States)

    Hamamda, M.; Bocvarski, V.; Perales, F.; Baudon, J.; Dutier, G.; Mainos, C.; Boustimi, M.; Ducloy, M.

    2010-11-01

    Semi-evanescent and evanescent matter waves produced by an atom wave packet impinging on a repulsive barrier can be back-refracted and reconstructed by the application of negative-index 'comoving' potential pulses. One shows that those collapses and revivals generate a matter wave confined on both sides of the barrier border ('surface matter wave') and should be observable via the retardation of atom reflection from the barrier interface. This property, joined to the possibility recently demonstrated of inducing negative refraction of atom waves, makes such potentials a matter-wave counterpart of negative-index materials or 'meta materials' well known in light optics.

  5. EXIT STRATEGY IN A TREAT-AND-EXTEND REGIMEN FOR EXUDATIVE AGE-RELATED MACULAR DEGENERATION.

    Science.gov (United States)

    Arendt, Petra; Yu, Siqing; Munk, Marion R; Ebneter, Andreas; Wolf, Sebastian; Zinkernagel, Martin S

    2017-11-17

    To evaluate the outcome of an exit strategy in a treat-and-extend regimen for neovascular age-related macular degeneration. Five hundred and ninety-eight eyes of 488 patients with neovascular age-related macular degeneration receiving intravitreal anti-vascular endothelial growth factor injections according to a treat-and-extend regimen were included in this retrospective study. A treat-and-extend regimen with either interval extension by 2 weeks or shortening by 1 week was used. "Exit criteria" were defined as 3 consecutive injections 16 weeks apart with stable findings after which the patient was exited from treatment and followed up at 3 to 4 monthly intervals without therapy. Best-corrected visual acuity, central retinal thickness at treatment initiation and termination, incidence of recurrence after treatment termination, presence of characteristics in the optical coherence tomography, duration of therapy, number and intervals of injections were analyzed. Seventeen percent of all included eyes met the exit criteria. The mean number of anti-vascular endothelial growth factor injections was 23.7 ± 14.7 with a mean treatment duration of 4.5 ± 2.5 years. Twelve percent reached exit with the minimal number of injections. Thirteen percent had recurrent disease after a mean of 37 ± 16 weeks. In the subgroup with recurrent disease, rate of pigment epithelial detachment at treatment termination was significantly higher than without recurrence (77% vs. 30%, P = 0.0018) with a significant higher proportion of serous pigment epithelial detachment (31% vs. 7%, P = 0.0247). The high percentage of patients meeting the exit criteria and the relatively low incidence of recurrences underline the usefulness of a predefined exit strategy. However, in a subgroup of patients, continuation of therapy may be advisable.This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is

  6. Hydraulic Model Tests on Modified Wave Dragon

    DEFF Research Database (Denmark)

    Hald, Tue; Lynggaard, Jakob

    are found in Hald and Lynggaard (2001). Model tests and reconstruction are carried out during the phase 3 project: ”Wave Dragon. Reconstruction of an existing model in scale 1:50 and sequentiel tests of changes to the model geometry and mass distribution parameters” sponsored by the Danish Energy Agency...... (DEA) wave energy programme. The tests will establish a well documented basis for the development of a 1:4.5 scale prototype planned for testing Nissum Bredning, a sea inlet on the Danish West Coast....

  7. Rossby Waves

    OpenAIRE

    2005-01-01

    tut quiz Tutorial Quiz Interactive Media Element This interactive tutorial reviews the mechanisms of Rossby waves. Rossby waves in both the northern and southern hemispheres are considered. The interactions involve answering simple fill-in-the-blank questions. Diagrams are used to illustrate some of the concepts reviewed. MR4322 Dynamic Meteorology

  8. Wave Dragon

    DEFF Research Database (Denmark)

    Tedd, James; Kofoed, Jens Peter; Friis-Madsen, Erik

    2008-01-01

    Since March 2003 a prototype of Wave Dragon has been tested in an inland sea in Denmark. This has been a great success with all subsystems tested and improved through working in an offshore environment. The project has proved the Wave Dragon device and has enabled the next stage, a production sized...

  9. Wave Star

    DEFF Research Database (Denmark)

    Kramer, Morten; Brorsen, Michael; Frigaard, Peter

    Nærværende rapport beskriver numeriske beregninger af den hydrodynamiske interaktion mellem 5 flydere i bølgeenergianlægget Wave Star.......Nærværende rapport beskriver numeriske beregninger af den hydrodynamiske interaktion mellem 5 flydere i bølgeenergianlægget Wave Star....

  10. Long-Term Exit-Site Gentamicin Prophylaxis and Gentamicin Resistance in a Peritoneal Dialysis Program.

    Science.gov (United States)

    Chen, Shan Shan; Sheth, Heena; Piraino, Beth; Bender, Filitsa

    2016-01-01

    ♦ Daily gentamicin cream exit-site prophylaxis reduces peritoneal dialysis (PD)-related gram-negative infections. However, there is a concern about the potential for increasing gentamicin resistance with the long-term use of prophylactic gentamicin. This study evaluated the incidence of gentamicin-resistant PD-related infections over more than 2 decades. ♦ Study data on prevalent PD patients were retrieved from a prospectively maintained institutional review board (IRB)-approved PD registry at a single center from January 1, 1991, to December 31, 2000, and January 1, 2004, to December 31, 2013. The rates of gram-negative infections, fungal infections and those infections with organisms resistant to gentamicin were examined for the 2 periods. Period 1 from 1991 to 2000 when S. aureus prophylaxis consisted initially of oral rifampin to treat nasal carriage with S. aureus, and was then daily exit-site mupirocin ointment for all PD patients, was compared to the period from 2004 to 2013 when daily exit-site gentamicin cream was prescribed as prophylaxis (Period 2). ♦ The study included a total of 444 PD patients (265 and 179 in Period 1 and Period 2, respectively). No significant difference was noted in demographics between the 2 periods except race. The gram-negative exit-site infection rates for Period 1 and Period 2 were 0.109 versus 0.027 (p gentamicin-resistant infections in each period. Fungal infections remained consistently low. ♦ Despite a decade of exit-site gentamicin prophylaxis, gentamicin-resistant PD-related infections and fungal infections remained very low and similar to the prior period. Copyright © 2016 International Society for Peritoneal Dialysis.

  11. Outlet plenum mixing for transient overpower conditions of a one-exit nozzle LMFBR

    Energy Technology Data Exchange (ETDEWEB)

    Howard, P.A.

    1978-04-01

    Two types of transient tests were employed to model a one-exit nozzle LMFBR outlet plenum. Water was used as a test fluid in the simulation of constant flowrates, Transient Overpower (TOP) conditions. In the first test, simulated fuel flow was 85% and blanket flow was 15%, whereas in the second test, the fuel flow was 100%. This allowed the assessment of the mitigating effects of blanket flow upon the exit nozzle temperature transient. The flow field was clearly three-dimensional, and a less active, though not stagnant, region was observed diametrically opposite the exit nozzle. During steady state, oscillations above the fuel-blanket interface were found to be small. This is attributed to the existence above the reactor core of a recirculating flow field, which served as an effective mixing agent. A simple lumped-parameter model, EXIT1, was developed to simulate TOP transient conditions for the test with both fuel and blanket flows. The predicted temperature profiles for various regions in the plenum were in good agreement with the experimental profiles, except for the region immediately above the reactor blanket. In devising the computer model, the temperature in this region was assumed to remain constant throughout the transient. However, this constant temperature did not prevail owing to the mixing that occurred in this region as a result of the recirculating flow field above the reactor core. The computer model can be readily modified to take into account the mixing due to this recirculation. In the test without blanket flow, good agreement between predictions and data was again obtained. In comparing results of the two tests, it was found that the blanket flow had only a small mitigating influence on the transient at the exit nozzle. The computer model can easily be extrapolated to reactor conditions.

  12. Two inhibitory systems and CKIs regulate cell cycle exit of mammalian cardiomyocytes after birth

    Energy Technology Data Exchange (ETDEWEB)

    Tane, Shoji; Okayama, Hitomi; Ikenishi, Aiko; Amemiya, Yuki [School of Life Sciences, Faculty of Medicine, Tottori University, Yonago 683-8503 (Japan); Nakayama, Keiichi I. [Medical Institute of Bioregulation, Kyushu University, Fukuoka 812-8582 (Japan); Takeuchi, Takashi, E-mail: takeuchi@med.tottori-u.ac.jp [School of Life Sciences, Faculty of Medicine, Tottori University, Yonago 683-8503 (Japan)

    2015-10-16

    Mammalian cardiomyocytes actively proliferate during embryonic stages, following which they exit their cell cycle after birth, and the exit is maintained. Previously, we showed that two inhibitory systems (the G1-phase inhibitory system: repression of cyclin D1 expression; the M-phase inhibitory system: inhibition of CDK1 activation) maintain the cell cycle exit of mouse adult cardiomyocytes. We also showed that two CDK inhibitors (CKIs), p21{sup Cip1} and p27{sup Kip1}, regulate the cell cycle exit in a portion of postnatal cardiomyocytes. It remains unknown whether the two inhibitory systems are involved in the cell cycle exit of postnatal cardiomyocytes and whether p21{sup Cip1} and p27{sup Kip1} also inhibit entry to M-phase. Here, we showed that more than 40% of cardiomyocytes entered an additional cell cycle by induction of cyclin D1 expression at postnatal stages, but M-phase entry was inhibited in the majority of cardiomyocytes. Marked cell cycle progression and endoreplication were observed in cardiomyocytes of p21{sup Cip1} knockout mice at 4 weeks of age. In addition, tri- and tetranucleated cardiomyocytes increased significantly in p21{sup Cip1} knockout mice. These data showed that the G1-phase inhibitory system and two CKIs (p21{sup Cip1} and p27{sup Kip1}) inhibit entry to an additional cell cycle in postnatal cardiomyocytes, and that the M-phase inhibitory system and p21{sup Cip1} inhibit M-phase entry of cardiomyocytes which have entered the additional cell cycle. - Highlights: • Many postnatal cardiomyocytes entered an additional cell cycle by cyclin D1 induction. • The majority of cardiomyocytes could not enter M-phase after cyclin D1 induction. • Cell cycle progressed markedly in p21{sup Cip1} knockout mice after postnatal day 14. • Tri- and tetranucleated cardiomyocytes increased in p21{sup Cip1} knockout mice.

  13. The relationship between substance use and exit security on psychiatric wards.

    Science.gov (United States)

    Simpson, Alan; Bowers, Len; Haglund, Kristina; Muir-Cochrane, Eimear; Nijman, Henk; Van der Merwe, Marie

    2011-03-01

    In this paper we report on the rates of drug/alcohol use on acute psychiatric wards in relation to levels and intensity of exit security measures. Many inpatient wards have become permanently locked, with staff concerned about the risk of patients leaving the ward and harming themselves or others, and of people bringing illicit substances into the therapeutic environment. In 2004/2005, a cross sectional survey on 136 acute psychiatric wards across three areas of England was undertaken. A comprehensive range of data including door locking and drug/alcohol use were collected over 6 months on each ward. In 2006, supplementary data on door locking and exit security were collected. Door locking, additional exit security measures and substance misuse rates of the 136 wards were analysed and the associations between these were investigated. No consistent relationships were found with exit security features, intensity of drug/alcohol monitoring procedures, or the locking of the ward door. There were indications that use of breath testing for alcohol might reduce usage and that the use of 'sniffer' dogs was associated with greater alcohol use. Greater exit security or locking of the ward door had no influence on rates of use of alcohol or illicit drugs by inpatients and thus cannot form part of any strategy to control substance use by inpatients. There are some grounds to believe that a greater use of screening might help reduce the frequency of alcohol/substance use on wards and may lead to a reduction in verbal abuse. © 2010 The Authors. Journal of Advanced Nursing © 2010 Blackwell Publishing Ltd.

  14. Numerical identification of blade exit angle effect on the performance for a multistage centrifugal pump impeller

    Directory of Open Access Journals (Sweden)

    Babayigit Osman

    2015-01-01

    Full Text Available Nowadays, single and multistage centrifugal pumps are widely used in industrial and mining enterprises. One of the most important components of a centrifugal pump is the impeller. The performance characteristics are related to the pump comprising the head and the overall efficiency rely a great deal on the impeller geometry. In this work, effects of blade exit angle change on hydraulic efficiency of a multi stage pump impeller are investigated via Ansys-Fluent computational fluid dynamics software for constant width impeller entrance and exit gates, blade numbers and blade thickness. Firstly, the flow volume of a centrifugal pump impeller is generated and then mesh structure is formed for the full impeller flow volume. Secondly, rotational periodic flow model are adopted in order to examine the effect of periodic flow assumption on the performance predictions. Corresponding to the available experimental data, inlet mass flow rate, outlet static pressure and rotation of impeller are taken as 0.02m3s-1, 450 kPa and 2950 rpm, respectively for the water fluid. No slip boundary condition is exposed to all solid of surface in the flow volume. The continuity and Navier-Stokes equations with the k-ε turbulence model and the standard wall functions are used. During the study, numerical analyses are conducted for the blade exit angle values of 18°, 20°, 25°, 30° and 35°. In consequence of the performed analyses, it is determined that hydraulic efficiency of the pump impeller value is changed between 81.0-84.6%. The most convenient blade exit angle that yields 84.6% hydraulic efficiency at is 18°. The obtained results show that the blade exit angle range has an impact on the centrifugal pump performance describing the pump head and the hydraulic efficiency.

  15. Wave Solutions

    CERN Document Server

    Christov, Ivan C

    2012-01-01

    In classical continuum physics, a wave is a mechanical disturbance. Whether the disturbance is stationary or traveling and whether it is caused by the motion of atoms and molecules or the vibration of a lattice structure, a wave can be understood as a specific type of solution of an appropriate mathematical equation modeling the underlying physics. Typical models consist of partial differential equations that exhibit certain general properties, e.g., hyperbolicity. This, in turn, leads to the possibility of wave solutions. Various analytical techniques (integral transforms, complex variables, reduction to ordinary differential equations, etc.) are available to find wave solutions of linear partial differential equations. Furthermore, linear hyperbolic equations with higher-order derivatives provide the mathematical underpinning of the phenomenon of dispersion, i.e., the dependence of a wave's phase speed on its wavenumber. For systems of nonlinear first-order hyperbolic equations, there also exists a general ...

  16. An Eclectic Approach to Loyalty-Promoting Instruments in Corporate Law: Revisiting Hirschman's Model of Exit, Voice, and Loyalty

    NARCIS (Netherlands)

    A.A. Bootsma (Bart)

    2013-01-01

    markdownabstract__Abstract__ This essay analyses the shareholder role in corporate governance in terms of Albert Hirschman's Exit, Voice, and Loyalty. The term 'exit' is embedded in a law & economics framework, while 'voice' relates to a corporate constitutional framework. The essay takes an

  17. Reoperative midface reconstruction.

    Science.gov (United States)

    Acero, Julio; García, Eloy

    2011-02-01

    Reoperative reconstruction of the midface is a challenging issue because of the complexity of this region and the severity of the aesthetic and functional sequela related to the absence or failure of a primary reconstruction. The different situations that can lead to the indication of a reoperative reconstructive procedure after previous oncologic ablative procedures in the midface are reviewed. Surgical techniques, anatomic problems, and limitations affecting the reoperative reconstruction in this region of the head and neck are discussed. Copyright © 2011 Elsevier Inc. All rights reserved.

  18. Muscle Activity Map Reconstruction from High Density Surface EMG Signals With Missing Channels Using Image Inpainting and Surface Reconstruction Methods.

    Science.gov (United States)

    Ghaderi, Parviz; Marateb, Hamid R

    2017-07-01

    The aim of this study was to reconstruct low-quality High-density surface EMG (HDsEMG) signals, recorded with 2-D electrode arrays, using image inpainting and surface reconstruction methods. It is common that some fraction of the electrodes may provide low-quality signals. We used variety of image inpainting methods, based on partial differential equations (PDEs), and surface reconstruction methods to reconstruct the time-averaged or instantaneous muscle activity maps of those outlier channels. Two novel reconstruction algorithms were also proposed. HDsEMG signals were recorded from the biceps femoris and brachial biceps muscles during low-to-moderate-level isometric contractions, and some of the channels (5-25%) were randomly marked as outliers. The root-mean-square error (RMSE) between the original and reconstructed maps was then calculated. Overall, the proposed Poisson and wave PDE outperformed the other methods (average RMSE 8.7 μVrms ± 6.1 μVrms and 7.5 μVrms ± 5.9 μVrms) for the time-averaged single-differential and monopolar map reconstruction, respectively. Biharmonic Spline, the discrete cosine transform, and the Poisson PDE outperformed the other methods for the instantaneous map reconstruction. The running time of the proposed Poisson and wave PDE methods, implemented using a Vectorization package, was 4.6 ± 5.7 ms and 0.6 ± 0.5 ms, respectively, for each signal epoch or time sample in each channel. The proposed reconstruction algorithms could be promising new tools for reconstructing muscle activity maps in real-time applications. Proper reconstruction methods could recover the information of low-quality recorded channels in HDsEMG signals.

  19. [Breast reconstruction after mastectomy].

    Science.gov (United States)

    Ho Quoc, C; Delay, E

    2013-02-01

    The mutilating surgery for breast cancer causes deep somatic and psychological sequelae. Breast reconstruction can mitigate these effects and permit the patient to help rebuild their lives. The purpose of this paper is to focus on breast reconstruction techniques and on factors involved in breast reconstruction. The methods of breast reconstruction are presented: objectives, indications, different techniques, operative risks, and long-term monitoring. Many different techniques can now allow breast reconstruction in most patients. Clinical cases are also presented in order to understand the results we expect from a breast reconstruction. Breast reconstruction provides many benefits for patients in terms of rehabilitation, wellness, and quality of life. In our mind, breast reconstruction should be considered more as an opportunity and a positive choice (the patient can decide to do it), than as an obligation (that the patient would suffer). The consultation with the surgeon who will perform the reconstruction is an important step to give all necessary informations. It is really important that the patient could speak again with him before undergoing reconstruction, if she has any doubt. The quality of information given by medical doctors is essential to the success of psychological intervention. This article was written in a simple, and understandable way to help gynecologists giving the best information to their patients. It is maybe also possible to let them a copy of this article, which would enable them to have a written support and would facilitate future consultation with the surgeon who will perform the reconstruction. Copyright © 2012. Published by Elsevier Masson SAS.

  20. Delayed breast implant reconstruction

    DEFF Research Database (Denmark)

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne

    2012-01-01

    We evaluated the association between radiation therapy and severe capsular contracture or reoperation after 717 delayed breast implant reconstruction procedures (288 1- and 429 2-stage procedures) identified in the prospective database of the Danish Registry for Plastic Surgery of the Breast during...... reconstruction approaches other than implants should be seriously considered among women who have received radiation therapy....

  1. Anatomical Individualized ACL Reconstruction

    Directory of Open Access Journals (Sweden)

    Amir Ata Rahnemai-Azar

    2016-10-01

    Full Text Available The anterior cruciate ligament (ACL is composed of two bundles, which work together to provide both antero-posterior and rotatory stability of the knee. Understanding the anatomy and function of the ACL plays a key role in management of patients with ACL injury. Anatomic ACL reconstruction aims to restore the function of the native ACL. Femoral and tibial tunnels should be placed in their anatomical location accounting for both the native ACL insertion site and bony landmarks. One main component of anatomical individualized ACL reconstruction is customizing the treatment according to each patient’s individual characteristics, considering preoperative and intraoperative evaluation of the native ACL and knee bony anatomy. Anatomical individualized reconstruction surgery should also aim to restore the size of the native ACL insertion as well. Using this concept, while single bundle ACL reconstruction can restore the function of the ACL in some patients, double bundle reconstruction is indicated in others to achieve optimal outcome.

  2. Rhineland exit?

    NARCIS (Netherlands)

    Bovenberg, A.L.; Teulings, C.

    2009-01-01

    We argue in favor of the shareholder model of the firm because assigning the full surplus of the firm to shareholders provides the best possible social insurance by diversifying firm-specific risks on capital markets. Coordination in wage bargaining and collective norms on what is proper

  3. Exit Prostitution

    DEFF Research Database (Denmark)

    Henriksen, Theresa Dyrvig; Mehlsen, Line; Kjær, Agnete Aslaug

    Fra 2012 til 2016 har man i Aalborg, Aarhus, København og Odense afprøvet metoden Critical Time Intervention (CTI) inden for prostitutionsområdet. Denne rapport evaluerer resultaterne. CTI har tidligere vist positive resultater i socialt arbejde med udsatte grupper, som fx hjemløse. På baggrund a...

  4. Consolidation Waves

    OpenAIRE

    Berg, Ward; Smit, Han

    2007-01-01

    textabstractThis paper explains why consolidation acquisitions occur in waves and it predicts the differing role each firm is likely to play in the consolidation game. We propose that whether a firm assumes the role of rival consolidator, target, or passive observer depends on the position of the firm relative to the entity that merges first. Our model predicts that an initial acquisition triggers a wave of follow-on acquisitions, where the process of asset accumulation by the consolidator is...

  5. Wave Star

    DEFF Research Database (Denmark)

    Kramer, Morten; Andersen, Thomas Lykke

    Nærværende rapport beskriver modelforsøg udført på Aalborg Universitet, Institut for Vand, Jord og Miljøteknik med bølgeenergianlægget Wave Star.......Nærværende rapport beskriver modelforsøg udført på Aalborg Universitet, Institut for Vand, Jord og Miljøteknik med bølgeenergianlægget Wave Star....

  6. Wave Star

    DEFF Research Database (Denmark)

    Kramer, Morten; Frigaard, Peter

    Nærværende rapport beskriver modelforsøg udført på Aalborg Universitet, Institut for Byggeri og Anlæg med bølgeenergianlæget Wave Star.......Nærværende rapport beskriver modelforsøg udført på Aalborg Universitet, Institut for Byggeri og Anlæg med bølgeenergianlæget Wave Star....

  7. Blast Waves

    CERN Document Server

    Needham, Charles E

    2010-01-01

    The primary purpose of this text is to document many of the lessons that have been learned during the author’s more than forty years in the field of blast and shock. The writing therefore takes on an historical perspective, in some sense, because it follows the author’s experience. The book deals with blast waves propagating in fluids or materials that can be treated as fluids. It begins by distinguishing between blast waves and the more general category of shock waves. It then examines several ways of generating blast waves, considering the propagation of blast waves in one, two and three dimensions as well as through the real atmosphere. One section treats the propagation of shocks in layered gases in a more detailed manner. The book also details the interaction of shock waves with structures in particular reflections, progressing from simple to complex geometries, including planar structures, two-dimensional structures such as ramps or wedges, reflections from heights of burst, and three-dimensional st...

  8. Variable actin dynamics requirement for the exit of different cargo from the trans-Golgi network.

    Science.gov (United States)

    Lázaro-Diéguez, Francisco; Colonna, Cecilia; Cortegano, Miguel; Calvo, María; Martínez, Susana E; Egea, Gustavo

    2007-08-07

    Efficient post-Golgi trafficking depends on microtubules, but actin filaments and actin-associated proteins are also postulated. Here we examined, by inverse fluorescence recovery after photobleaching, the role of actin dynamics in the exit from the TGN of fluorescent-tagged apical or basolateral and raft or non-raft-associated cargoes. Either the actin-stabilizing jasplakinolide or the actin-depolymerising latrunculin B variably but significantly inhibited post-Golgi traffic of non-raft associated apical p75NTR and basolateral VSV-G cargoes. The TGN-exit of the apical-destined VSV-G mutant was impaired only by latrunculin B. Strikingly, the raft-associated GPI-anchor protein was not affected by either actin toxin. Results indicate that actin dynamics participates in the TGN egress of both apical- and basolateral-targeted proteins but is not needed for apical raft-associated cargo.

  9. Showing Where To Go by Maps or Pictures: An Empirical Case Study at Subway Exits

    Science.gov (United States)

    Ishikawa, Toru; Yamazaki, Tetsuo

    This study empirically examined the effectiveness of different methods of presenting route information on a mobile navigation sysyem, for accurate and effortless orientation at subway exits. Specifically, it compared participants’ spatial orientation performance with pictures and maps, in relation to the levels of their spatial ability. Participants identified the directions toward the goals after coming onto the ground faster when viewing pictures than when viewing maps. Spatial orientation with maps was more difficult than that with pictures at exits where body rotation was necessary, especially for people with low mental-rotation ability. In contrast, pictures were equally effective for people with low and high mental-rotation ability. Reasons for the effectiveness of pictures and possibilities of using other presentation formats are discussed.

  10. Radiation degradation of aromatic pollutants exit in wastewater and ph dependence

    CERN Document Server

    Takriti, S

    2002-01-01

    The effect of gamma radiation on the degradation of phenol (hydroxybenzene), resorcinol (1,3 dihydroxybenzen) and hydroquinone (1,4 dihydroxybenzen) exit in waste water was investigated. The concentrations of these pollutants as well as the irradiated solution ph were studied. The results showed that the phenol is very resistance against the radiation doses comparing the other phenol compounds. Phenol was also a product of radiolysis of resorcinol and hydroquinone. On the other hand, the acid phase of the irradiation sample increased the degradation rate of pollutants. Spectrophotometer (UV-VIS) and chromatography (HPLC) were used to monitor the analysis of the radiation product solution. The results illustrated the existing of many substances such as organic alcohol, aldehyde, ketone and acidic functional groups as a final radiation products. The degradation of benzene, monochlorobenzene (CB) and 1,2 dichlorobenzene (1,2 DCB) exit in waste water by gamma irradiation was investigated. The effect of the irradi...

  11. First-passage and first-exit times of a Bessel-like stochastic process.

    Science.gov (United States)

    Martin, Edgar; Behn, Ulrich; Germano, Guido

    2011-05-01

    We study a stochastic process X(t) which is a particular case of the Rayleigh process and whose square is the Bessel process, with various applications in physics, chemistry, biology, economics, finance, and other fields. The stochastic differential equation is dX(t)=(nD/X(t))dt+√(2D)dW(t), where W(t) is the Wiener process. The drift term can arise from a logarithmic potential or from taking X(t) as the norm of a multidimensional random walk. Due to the singularity of the drift term for X(t)=0, different natures of boundary at the origin arise depending on the real parameter n: entrance, exit, and regular. For each of them we calculate analytically and numerically the probability density functions of first-passage times or first-exit times. Nontrivial behavior is observed in the case of a regular boundary.

  12. Probation foster care as an outcome for children exiting child welfare foster care.

    Science.gov (United States)

    Jonson-Reid, Melissa; Barth, Richard P

    2003-07-01

    Little research has been done to help us understand what happens to children who exit child welfare foster care for reasons other than emancipation. Almost no research exists to help us understand out-of-home placement supervised by other providers of children's social services such as juvenile probation or mental health. This study examined school-age children who entered out-of-home placement supervised by probation departments after they left child welfare foster or group care. Instability in child welfare placements significantly increased the risk of a transition to probation foster care. Among the children exiting child welfare placements, those who had entered their first spell in care at ages 12 through 14 or were first removed because of sexual abuse or neglect were at greater risk of probation out-of-home placement. Implications for social work policy and services are discussed.

  13. Wave Generation Theory

    DEFF Research Database (Denmark)

    Frigaard, Peter; Høgedal, Michael; Christensen, Morten

    The intention of this manual is to provide some formulas and techniques which can be used for generating waves in hydraulic laboratories. Both long crested waves (2-D waves) and short crested waves (3-D waves) are considered....

  14. A conserved chloramphenicol binding site at the entrance to the ribosomal peptide exit tunnel

    DEFF Research Database (Denmark)

    Long, Katherine S; Porse, Bo T

    2003-01-01

    , of E.coli 23S rRNA and G2084 (2058 in E.coli numbering) in domain V of H.halobium 23S rRNA. The modification sites overlap with a portion of the macrolide binding site and cluster at the entrance to the peptide exit tunnel. The data correlate with the recently reported chloramphenicol binding site...... on an archaeal ribosome and suggest that a similar binding site is present on the E.coli ribosome....

  15. Runway Exit Designs for Capacity Improvement Demonstrations. Phase 2. Computer Model Development

    Science.gov (United States)

    1992-01-15

    simplify the number of internal computations of the model thus reducing CPU time. 2.3.2 Turnoff Algorithm Validation Procedure The validation of a...most inten- sive computational algorithm in REDIM 2.0, however, is the optimization of exit loca- tions consuming approximately 80% of the CPU time...with a 80286 or 80386 microprocessors *A math coprocessor *EGA or VGA color monitor -HP laser printer or Epson FX-80 dot-matrix printer -I MB minimum of

  16. Visual barriers to prevent ambulatory Alzheimer's patients from exiting through an emergency door.

    Science.gov (United States)

    Namazi, K H; Rosner, T T; Calkins, M P

    1989-10-01

    Mobility combined with impaired mental functioning presents safety risks for Alzheimer's patients and poses an ethical dilemma for staff. This study, conducted on an Alzheimer's unit, tested seven different visual barrier conditions for reducing patient exists. Findings indicate that exiting was eliminated under two conditions. The results suggest visual agnosia, the inability to interpret what the eye sees, may be utilized as a tool in managing wandering behavior of Alzheimer's patients.

  17. Comparing the Impact of a High School Exit Examination on Biology Teachers’ Instructional Practices

    OpenAIRE

    Kenneth E. Vogler; G. Nathan Carnes

    2014-01-01

    The purpose of this study was to compare the impact of a high school exit examination with different consequences attached to the results on biology teachers’ instructional practices in Mississippi and Tennessee. Self-reported survey data were obtained from a representative sample of teachers who taught the same content tested on their respective state’s high-stakes graduation examination. An analysis showed that both groups used a balance of student-centered (e.g., critical-thinking activiti...

  18. Transmedia as experimental ethnography: The Exit Zero Project, deindustrialization, and the politics of nostalgia

    OpenAIRE

    Walley, Christine

    2015-01-01

    How might “transmedia” approaches—or working across media—fit into histories of textual and visual innovation within anthropology, and what might they contribute to the discipline in the current moment? I explore this question through the Exit Zero Project, which includes a book, documentary film, and planned interactive website that examine the impact of deindustrialization on Southeast Chicago and the relationship between industrial job loss and expanding class inequalities in the United St...

  19. Exit, Voice, And Loyalty In The Industrial District: The Case Of Prato

    OpenAIRE

    Gabi Dei Ottati

    2000-01-01

    In this paper the "exit, voice and loyalty" approach by Albert O. Hirschman is applied to the case of the rise and evolution of the Prato industrial district, from post-war days until now. This is done, not so much to gain a better understanding of the specific events in Prato, but rather to shed light on the recuperation mechanisms that characterise the fundamental economic relations within the industrial district: i.e. labour relations, subcontracting relations, and relations between firms....

  20. Numerical identification of blade exit angle effect on the performance for a multistage centrifugal pump impeller

    OpenAIRE

    Babayigit Osman; Kocaaslan Osman; Aksoy Muharrem Hilmi; Guleren Kursad Melih; Ozgoren Muammer

    2015-01-01

    Nowadays, single and multistage centrifugal pumps are widely used in industrial and mining enterprises. One of the most important components of a centrifugal pump is the impeller. The performance characteristics are related to the pump comprising the head and the overall efficiency rely a great deal on the impeller geometry. In this work, effects of blade exit angle change on hydraulic efficiency of a multi stage pump impeller are investigated via Ansys-Fluent computational fluid dynamics sof...

  1. R2 & NE: NAVTEQ 2011 Q3 Exit Points for the United States, including Puerto Rico and the US Virgin Islands in SDC Format

    Data.gov (United States)

    U.S. Environmental Protection Agency — The EXITS layer contains point representations of the locations of exits, typically on controlled access roads such as motorways and freeways. Controlled access...

  2. Exit of Plasmodium sporozoites from oocysts is an active process that involves the circumsporozoite protein.

    Directory of Open Access Journals (Sweden)

    2005-09-01

    Full Text Available Plasmodium sporozoites develop within oocysts residing in the mosquito midgut. Mature sporozoites exit the oocysts, enter the hemolymph, and invade the salivary glands. The circumsporozoite (CS protein is the major surface protein of salivary gland and oocyst sporozoites. It is also found on the oocyst plasma membrane and on the inner surface of the oocyst capsule. CS protein contains a conserved motif of positively charged amino acids: region II-plus, which has been implicated in the initial stages of sporozoite invasion of hepatocytes. We investigated the function of region II-plus by generating mutant parasites in which the region had been substituted with alanines. Mutant parasites produced normal numbers of sporozoites in the oocysts, but the sporozoites were unable to exit the oocysts. In in vitro as well, there was a profound delay, upon trypsin treatment, in the release of mutant sporozoites from oocysts. We conclude that the exit of sporozoites from oocysts is an active process that involves the region II-plus of CS protein. In addition, the mutant sporozoites were not infective to young rats. These findings provide a new target for developing reagents that interfere with the transmission of malaria.

  3. The Ribosomal Protein uL22 Modulates the Shape of the Protein Exit Tunnel.

    Science.gov (United States)

    Wekselman, Itai; Zimmerman, Ella; Davidovich, Chen; Belousoff, Matthew; Matzov, Donna; Krupkin, Miri; Rozenberg, Haim; Bashan, Anat; Friedlander, Gilgi; Kjeldgaard, Jette; Ingmer, Hanne; Lindahl, Lasse; Zengel, Janice M; Yonath, Ada

    2017-08-01

    Erythromycin is a clinically useful antibiotic that binds to an rRNA pocket in the ribosomal exit tunnel. Commonly, resistance to erythromycin is acquired by alterations of rRNA nucleotides that interact with the drug. Mutations in the β hairpin of ribosomal protein uL22, which is rather distal to the erythromycin binding site, also generate resistance to the antibiotic. We have determined the crystal structure of the large ribosomal subunit from Deinococcus radiodurans with a three amino acid insertion within the β hairpin of uL22 that renders resistance to erythromycin. The structure reveals a shift of the β hairpin of the mutated uL22 toward the interior of the exit tunnel, triggering a cascade of structural alterations of rRNA nucleotides that propagate to the erythromycin binding pocket. Our findings support recent studies showing that the interactions between uL22 and specific sequences within nascent chains trigger conformational rearrangements in the exit tunnel. Copyright © 2017 Elsevier Ltd. All rights reserved.

  4. Pitx2 expression promotes p21 expression and cell cycle exit in neural stem cells.

    Science.gov (United States)

    Heldring, Nina; Joseph, Bertrand; Hermanson, Ola; Kioussi, Chrissa

    2012-11-01

    Cortical development is a complex process that involves many events including proliferation, cell cycle exit and differentiation that need to be appropriately synchronized. Neural stem cells (NSCs) isolated from embryonic cortex are characterized by their ability of self-renewal under continued maintenance of multipotency. Cell cycle progression and arrest during development is regulated by numerous factors, including cyclins, cyclin dependent kinases and their inhibitors. In this study, we exogenously expressed the homeodomain transcription factor Pitx2, usually expressed in postmitotic progenitors and neurons of the embryonic cortex, in NSCs with low expression of endogenous Pitx2. We found that Pitx2 expression induced a rapid decrease in proliferation associated with an accumulation of NSCs in G1 phase. A search for potential cell cycle inhibitors responsible for such cell cycle exit of NSCs revealed that Pitx2 expression caused a rapid and dramatic (≉20-fold) increase in expression of the cell cycle inhibitor p21 (WAF1/Cip1). In addition, Pitx2 bound directly to the p21 promoter as assessed by chromatin immunoprecipitation (ChIP) in NSCs. Surprisingly, Pitx2 expression was not associated with an increase in differentiation markers, but instead the expression of nestin, associated with undifferentiated NSCs, was maintained. Our results suggest that Pitx2 promotes p21 expression and induces cell cycle exit in neural progenitors.

  5. Labour market entries and exits of women from different origin countries in the UK.

    Science.gov (United States)

    Khoudja, Yassine; Platt, Lucinda

    2018-01-01

    Labour force participation rates of women differ strongly by ethnic origin. Even though existing research using cross-sectional studies has demonstrated that part of these differences can be attributed to compositional differences in human capital, household conditions and gender attitudes, residual 'ethnic effects' typically remain. To further our understanding of women's labour market behaviour across ethnic groups, we use a large-scale longitudinal study and apply a dynamic perspective to examine how far relevant life-course events in addition to individual characteristics, gender attitudes and religiosity contribute to the explanation of ethnic differences in women's labour force entries and exits in the UK. Our findings show that, adjusting for all these factors, Indian and Caribbean women do not differ from White majority women in their labour force entry and exit probabilities but that Pakistani and Bangladeshi women are less likely to enter and more likely to exit the labour market, whereas Black African women have higher entry rates. We also find that relations between life-course events and labour market transitions differ by ethnic group. Most notably, Pakistani and Bangladeshi women's labour market transitions are less sensitive to child-bearing and Caribbean women's transitions less sensitive to partnership changes than other women's. Copyright © 2017 Elsevier Inc. All rights reserved.

  6. Effects of inlet distortion on gas turbine combustion chamber exit temperature profiles

    Science.gov (United States)

    Maqsood, Omar Shahzada

    Damage to a nozzle guide vane or blade, caused by non-uniform temperature distributions at the combustion chamber exit, is deleterious to turbine performance and can lead to expensive and time consuming overhaul and repair. A test rig was designed and constructed for the Allison 250-C20B combustion chamber to investigate the effects of inlet air distortion on the combustion chamber's exit temperature fields. The rig made use of the engine's diffuser tubes, combustion case, combustion liner, and first stage nozzle guide vane shield. Rig operating conditions simulated engine cruise conditions, matching the quasi-non-dimensional Mach number, equivalence ratio and Sauter mean diameter. The combustion chamber was tested with an even distribution of inlet air and a 4% difference in airflow at either side. An even distribution of inlet air to the combustion chamber did not create a uniform temperature profile and varying the inlet distribution of air exacerbated the profile's non-uniformity. The design of the combustion liner promoted the formation of an oval-shaped toroidal vortex inside the chamber, creating localized hot and cool sections separated by 90° that appeared in the exhaust. Uneven inlet air distributions skewed the oval vortex, increasing the temperature of the hot section nearest the side with the most mass flow rate and decreasing the temperature of the hot section on the opposite side. Keywords: Allison 250, Combustion, Dual-Entry, Exit Temperature Profile, Gas Turbine, Pattern Factor, Reverse Flow.

  7. [Suicide with exit bags: circumstances and special problem situations in assisted suicide].

    Science.gov (United States)

    Grellner, Wolfgang; Anders, Sven; Tsokos, Michael; Wilske, Jochen

    2002-01-01

    So-called exit bags are voluminous, transparent plastic bags, each with a collar to go round the neck, and a Velcro fastening. In conjunction with the consumption of sleeping pills, the bags are recommended as an aid to commit suicide by organizations in favour of "humane death". It is reported on four such suicides by elderly people between 79 and 87 years of age. In two of these cases, there was assistance in committing suicide, one corresponding to a suicide protocol from the Swiss organization for euthanasia, EXIT. In two cases, detailed instructions for committing suicide were found. The morphological findings were not very specific in any of the cases. If the plastic bags are removed by a third party, this type of suicide may remain undetected even after performance of an autopsy. Exit bags tend to be used by older people with either real or feared life-threatening illnesses, in suicides which have usually been planned for some time. From the criminological point of view, the possible active participation of other persons in pulling the covering over the head can often not be proved. Assisting a suicide, in the sense of giving instructions on how to accomplish it, is not punishable in German law.

  8. Quiescence Exit of Tert+ Stem Cells by Wnt/β-Catenin Is Indispensable for Intestinal Regeneration

    Directory of Open Access Journals (Sweden)

    Han Na Suh

    2017-11-01

    Full Text Available Fine control of stem cell maintenance and activation is crucial for tissue homeostasis and regeneration. However, the mechanism of quiescence exit of Tert+ intestinal stem cells (ISCs remains unknown. Employing a Tert knockin (TertTCE/+ mouse model, we found that Tert+ cells are long-term label-retaining self-renewing cells, which are partially distinguished from the previously identified +4 ISCs. Tert+ cells become mitotic upon irradiation (IR injury. Conditional ablation of Tert+ cells impairs IR-induced intestinal regeneration but not intestinal homeostasis. Upon IR injury, Wnt signaling is specifically activated in Tert+ cells via the ROS-HIFs-transactivated Wnt2b signaling axis. Importantly, conditional knockout of β-catenin/Ctnnb1 in Tert+ cells undermines IR-induced quiescence exit of Tert+ cells, which subsequently impedes intestinal regeneration. Our results that Wnt-signaling-induced activation of Tert+ ISCs is indispensable for intestinal regeneration unveil the underlying mechanism for how Tert+ stem cells undergo quiescence exit upon tissue injury.

  9. A method for calculating strut and splitter plate noise in exit ducts: Theory and verification

    Science.gov (United States)

    Fink, M. R.

    1978-01-01

    Portions of a four-year analytical and experimental investigation relative to noise radiation from engine internal components in turbulent flow are summarized. Spectra measured for such airfoils over a range of chord, thickness ratio, flow velocity, and turbulence level were compared with predictions made by an available rigorous thin-airfoil analytical method. This analysis included the effects of flow compressibility and source noncompactness. Generally good agreement was obtained. This noise calculation method for isolated airfoils in turbulent flow was combined with a method for calculating transmission of sound through a subsonic exit duct and with an empirical far-field directivity shape. These three elements were checked separately and were individually shown to give close agreement with data. This combination provides a method for predicting engine internally generated aft-radiated noise from radial struts and stators, and annular splitter rings. Calculated sound power spectra, directivity, and acoustic pressure spectra were compared with the best available data. These data were for noise caused by a fan exit duct annular splitter ring, larger-chord stator blades, and turbine exit struts.

  10. Helping Survivors of Human Trafficking: A Systematic Review of Exit and Postexit Interventions.

    Science.gov (United States)

    Dell, Nathaniel A; Maynard, Brandy R; Born, Kara R; Wagner, Elizabeth; Atkins, Bonnie; House, Whitney

    2017-01-01

    Human trafficking is a global problem and results in deleterious psychological, social, and physical effects on the lives of those who are trafficked; however, it is not clear how to best intervene with survivors. The purpose of this review was to synthesize the evidence of exit and postexit intervention programs for survivors of human trafficking to inform practice and research. Systematic review methods were used to search, select, and extract data from published and unpublished experimental, quasi-experimental, and preexperimental studies that assessed the effects of any exit or postexit interventions for victims of human trafficking. The authors searched eight databases, reviewed bibliographies, and conducted forward citation searches from relevant reports and prior reviews to find studies authored between 2005 and 2015. The search yielded six eligible studies that included 155 female and 6 male survivors from four countries. Interventions were diverse, with three using a trauma-informed approach. Authors measured a myriad of outcomes, including mental health, social network, community reintegration, and employment; however, the quality of most studies was poor. Evidence of effects of exit and postexit interventions is sparse, and much of the research is poorly designed and executed; however, the needs of trafficking survivors are complex and effective interventions are desperately needed. Implications for practice and research are discussed.

  11. Exit competencies in pathology and laboratory medicine for graduating medical students: the Canadian approach.

    Science.gov (United States)

    Ford, Jason; Pambrun, Chantale

    2015-05-01

    Physicians in every medical and surgical field must be able to use pathology concepts and skills in their practice: for example, they must order and interpret the correct laboratory tests, they must use their understanding of pathogenesis to diagnose and treat, and they must work with the laboratory to care for their patients. These important concepts and skills may be ignored by medical schools and even national/international organizations setting graduation expectations for medical students. There is an evolving international consensus about the importance of exit competencies for medical school graduates, which define the measurable or observable behaviors each graduate must be able to demonstrate. The Canadian Association of Pathologists (CAP) Education Group set out to establish the basic competencies in pathology and laboratory medicine which should be expected of every medical graduate: not competencies for pathologists, but for medical graduates who intend to enter any residency program. We defined 4 targets for pathology and laboratory medicine exit competencies: that they represent only measurable behaviors, that they be clinically focused, that they be generalizable to every medical graduate, and that the final competency document be user-friendly. A set of competencies was developed iteratively and underwent final revision at the 2012 CAP annual meeting. These competencies were subsequently endorsed by the CAP executive and the Canadian Leadership Council on Laboratory Medicine. This clinically focused consensus document provides the first comprehensive list of exit competencies in pathology and laboratory medicine for undergraduate medical education. Copyright © 2015 Elsevier Inc. All rights reserved.

  12. Wave and particle in molecular interference lithography.

    Science.gov (United States)

    Juffmann, Thomas; Truppe, Stefan; Geyer, Philipp; Major, András G; Deachapunya, Sarayut; Ulbricht, Hendrik; Arndt, Markus

    2009-12-31

    The wave-particle duality of massive objects is a cornerstone of quantum physics and a key property of many modern tools such as electron microscopy, neutron diffraction or atom interferometry. Here we report on the first experimental demonstration of quantum interference lithography with complex molecules. Molecular matter-wave interference patterns are deposited onto a reconstructed Si(111) 7x7 surface and imaged using scanning tunneling microscopy. Thereby both the particle and the quantum wave character of the molecules can be visualized in one and the same image. This new approach to nanolithography therefore also represents a sensitive new detection scheme for quantum interference experiments.

  13. Hybrid spectral CT reconstruction

    Science.gov (United States)

    Clark, Darin P.

    2017-01-01

    Current photon counting x-ray detector (PCD) technology faces limitations associated with spectral fidelity and photon starvation. One strategy for addressing these limitations is to supplement PCD data with high-resolution, low-noise data acquired with an energy-integrating detector (EID). In this work, we propose an iterative, hybrid reconstruction technique which combines the spectral properties of PCD data with the resolution and signal-to-noise characteristics of EID data. Our hybrid reconstruction technique is based on an algebraic model of data fidelity which substitutes the EID data into the data fidelity term associated with the PCD reconstruction, resulting in a joint reconstruction problem. Within the split Bregman framework, these data fidelity constraints are minimized subject to additional constraints on spectral rank and on joint intensity-gradient sparsity measured between the reconstructions of the EID and PCD data. Following a derivation of the proposed technique, we apply it to the reconstruction of a digital phantom which contains realistic concentrations of iodine, barium, and calcium encountered in small-animal micro-CT. The results of this experiment suggest reliable separation and detection of iodine at concentrations ≥ 5 mg/ml and barium at concentrations ≥ 10 mg/ml in 2-mm features for EID and PCD data reconstructed with inherent spatial resolutions of 176 μm and 254 μm, respectively (point spread function, FWHM). Furthermore, hybrid reconstruction is demonstrated to enhance spatial resolution within material decomposition results and to improve low-contrast detectability by as much as 2.6 times relative to reconstruction with PCD data only. The parameters of the simulation experiment are based on an in vivo micro-CT experiment conducted in a mouse model of soft-tissue sarcoma. Material decomposition results produced from this in vivo data demonstrate the feasibility of distinguishing two K-edge contrast agents with a spectral

  14. Hybrid spectral CT reconstruction.

    Directory of Open Access Journals (Sweden)

    Darin P Clark

    Full Text Available Current photon counting x-ray detector (PCD technology faces limitations associated with spectral fidelity and photon starvation. One strategy for addressing these limitations is to supplement PCD data with high-resolution, low-noise data acquired with an energy-integrating detector (EID. In this work, we propose an iterative, hybrid reconstruction technique which combines the spectral properties of PCD data with the resolution and signal-to-noise characteristics of EID data. Our hybrid reconstruction technique is based on an algebraic model of data fidelity which substitutes the EID data into the data fidelity term associated with the PCD reconstruction, resulting in a joint reconstruction problem. Within the split Bregman framework, these data fidelity constraints are minimized subject to additional constraints on spectral rank and on joint intensity-gradient sparsity measured between the reconstructions of the EID and PCD data. Following a derivation of the proposed technique, we apply it to the reconstruction of a digital phantom which contains realistic concentrations of iodine, barium, and calcium encountered in small-animal micro-CT. The results of this experiment suggest reliable separation and detection of iodine at concentrations ≥ 5 mg/ml and barium at concentrations ≥ 10 mg/ml in 2-mm features for EID and PCD data reconstructed with inherent spatial resolutions of 176 μm and 254 μm, respectively (point spread function, FWHM. Furthermore, hybrid reconstruction is demonstrated to enhance spatial resolution within material decomposition results and to improve low-contrast detectability by as much as 2.6 times relative to reconstruction with PCD data only. The parameters of the simulation experiment are based on an in vivo micro-CT experiment conducted in a mouse model of soft-tissue sarcoma. Material decomposition results produced from this in vivo data demonstrate the feasibility of distinguishing two K-edge contrast agents with

  15. Hybrid spectral CT reconstruction.

    Science.gov (United States)

    Clark, Darin P; Badea, Cristian T

    2017-01-01

    Current photon counting x-ray detector (PCD) technology faces limitations associated with spectral fidelity and photon starvation. One strategy for addressing these limitations is to supplement PCD data with high-resolution, low-noise data acquired with an energy-integrating detector (EID). In this work, we propose an iterative, hybrid reconstruction technique which combines the spectral properties of PCD data with the resolution and signal-to-noise characteristics of EID data. Our hybrid reconstruction technique is based on an algebraic model of data fidelity which substitutes the EID data into the data fidelity term associated with the PCD reconstruction, resulting in a joint reconstruction problem. Within the split Bregman framework, these data fidelity constraints are minimized subject to additional constraints on spectral rank and on joint intensity-gradient sparsity measured between the reconstructions of the EID and PCD data. Following a derivation of the proposed technique, we apply it to the reconstruction of a digital phantom which contains realistic concentrations of iodine, barium, and calcium encountered in small-animal micro-CT. The results of this experiment suggest reliable separation and detection of iodine at concentrations ≥ 5 mg/ml and barium at concentrations ≥ 10 mg/ml in 2-mm features for EID and PCD data reconstructed with inherent spatial resolutions of 176 μm and 254 μm, respectively (point spread function, FWHM). Furthermore, hybrid reconstruction is demonstrated to enhance spatial resolution within material decomposition results and to improve low-contrast detectability by as much as 2.6 times relative to reconstruction with PCD data only. The parameters of the simulation experiment are based on an in vivo micro-CT experiment conducted in a mouse model of soft-tissue sarcoma. Material decomposition results produced from this in vivo data demonstrate the feasibility of distinguishing two K-edge contrast agents with a spectral

  16. Head and Neck Reconstruction.

    Science.gov (United States)

    Wong, Shannon; Melin, Alyson; Reilly, Debra

    2017-10-01

    Management of head and neck burns involves acute and intermediate phases. Acutely, the goals are establish a secure airway and treat life-threatening injuries. Then, optimize nutrition, assess extent of the burn, perform local wound care, and provide eye protection. Management depends on the degree of the head and neck burn. Postinjury splinting and rehabilitation are vital to healing. After the acute inflammation has resolved and the scars have matured, reconstruction begins with the goals of restoring both function and aesthetics. Reconstruction ranges from simple scar release, to skin grafting, and possibly free flap reconstruction. Copyright © 2017 Elsevier Inc. All rights reserved.

  17. Efficient Wave Energy Amplification with Wave Reflectors

    OpenAIRE

    Kramer, Morten Mejlhede; Frigaard, Peter Bak

    2002-01-01

    Wave Energy Converters (WEC's) extract wave energy from a limited area, often a single point or line even though the wave energy is generally spread out along the wave crest. By the use of wave reflectors (reflecting walls) the wave energy is effectively focused and increased to approximately 130-140%. In the paper a procedure for calculating the efficiency and optimizing the geometry of wave reflectors are described, this by use of a 3D boundary element method. The calculations are verified ...

  18. Forging Provincial Reconstruction Teams

    National Research Council Canada - National Science Library

    Honore, Russel L; Boslego, David V

    2007-01-01

    The Provincial Reconstruction Team (PRT) training mission completed by First U.S. Army in April 2006 was a joint Service effort to meet a requirement from the combatant commander to support goals in Afghanistan...

  19. Reconstructions of eyelid defects

    Directory of Open Access Journals (Sweden)

    Nirmala Subramanian

    2011-01-01

    Full Text Available Eyelids are the protective mechanism of the eyes. The upper and lower eyelids have been formed for their specific functions by Nature. The eyelid defects are encountered in congenital anomalies, trauma, and postexcision for neoplasm. The reconstructions should be based on both functional and cosmetic aspects. The knowledge of the basic anatomy of the lids is a must. There are different techniques for reconstructing the upper eyelid, lower eyelid, and medial and lateral canthal areas. Many a times, the defects involve more than one area. For the reconstruction of the lid, the lining should be similar to the conjunctiva, a cover by skin and the middle layer to give firmness and support. It is important to understand the availability of various tissues for reconstruction. One layer should have the vascularity to support the other layer which can be a graft. A proper plan and execution of it is very important.

  20. Tessellation reconstruction techniques

    NARCIS (Netherlands)

    de Weygaert, RV; Schaap, W; Banday, AJ; Zaroubi, S; Bartelmann, M

    2001-01-01

    The application of Voronoi and Delaunay tessellation based methods for reconstructing continuous fields from discretely sampled data sets is discussed. The succesfull operation as "multidimensional interpolation" method is corroborated through their ability to reproduce even intricate statistical

  1. Prairie Reconstruction Initiative Project

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The purpose of the Prairie Reconstruction Initiative Advisory Team (PRIAT) is to identify and take steps to resolve uncertainties in the process of prairie...

  2. Lamb Wave Tomography for Corrosion Mapping

    Science.gov (United States)

    Hinders, Mark K.; McKeon, James C. P.

    1999-01-01

    As the world-wide civil aviation fleet continues to age, methods for accurately predicting the presence of structural flaws-such as hidden corrosion-that compromise airworthiness become increasingly necessary. Ultrasonic guided waves, Lamb waves, allow large sections of aircraft structures to be rapidly inspected. However, extracting quantitative information from Lamb wave data has always involved highly trained personnel with a detailed knowledge of mechanical-waveguide physics. Our work focuses on using a variety of different tomographic reconstruction techniques to graphically represent the Lamb wave data in images that can be easily interpreted by technicians. Because the velocity of Lamb waves depends on thickness, we can convert the travel times of the fundamental Lamb modes into a thickness map of the inspection region. In this paper we show results for the identification of single or multiple back-surface corrosion areas in typical aluminum aircraft skin structures.

  3. Wave-plate structures, power selective optical filter devices, and optical systems using same

    Science.gov (United States)

    Koplow, Jeffrey P [San Ramon, CA

    2012-07-03

    In an embodiment, an optical filter device includes an input polarizer for selectively transmitting an input signal. The device includes a wave-plate structure positioned to receive the input signal, which includes first and second substantially zero-order, zero-wave plates arranged in series with and oriented at an angle relative to each other. The first and second zero-wave plates are configured to alter a polarization state of the input signal passing in a manner that depends on the power of the input signal. Each zero-wave plate includes an entry and exit wave plate each having a fast axis, with the fast axes oriented substantially perpendicular to each other. Each entry wave plate is oriented relative to a transmission axis of the input polarizer at a respective angle. An output polarizer is positioned to receive a signal output from the wave-plate structure and selectively transmits the signal based on the polarization state.

  4. 3D heart reconstruction

    OpenAIRE

    Roxo, Diogo

    2011-01-01

    The purpose of this thesis was to achieve a 3D reconstruction of the four heart chambers using 2D echocardiographic images. A level set algorithm based on the phase symmetry approach and on a new logarithmic based stopping function was used to extract simultaneously the four heart cavities from these images in a fully automatic way. However to proceed to the 3D reconstruction using the segmented images, it was first necessary to satisfy clinical practise requirements. This means that the algo...

  5. Source Signals Separation and Reconstruction Following Principal Component Analysis

    Directory of Open Access Journals (Sweden)

    WANG Cheng

    2014-02-01

    Full Text Available For separation and reconstruction of source signals from observed signals problem, the physical significance of blind source separation modal and independent component analysis is not very clear, and its solution is not unique. Aiming at these disadvantages, a new linear and instantaneous mixing model and a novel source signals separation reconstruction solving method from observed signals based on principal component analysis (PCA are put forward. Assumption of this new model is statistically unrelated rather than independent of source signals, which is different from the traditional blind source separation model. A one-to-one relationship between linear and instantaneous mixing matrix of new model and linear compound matrix of PCA, and a one-to-one relationship between unrelated source signals and principal components are demonstrated using the concept of linear separation matrix and unrelated of source signals. Based on this theoretical link, source signals separation and reconstruction problem is changed into PCA of observed signals then. The theoretical derivation and numerical simulation results show that, in despite of Gauss measurement noise, wave form and amplitude information of unrelated source signal can be separated and reconstructed by PCA when linear mixing matrix is column orthogonal and normalized; only wave form information of unrelated source signal can be separated and reconstructed by PCA when linear mixing matrix is column orthogonal but not normalized, unrelated source signal cannot be separated and reconstructed by PCA when mixing matrix is not column orthogonal or linear.

  6. Finite Amplitude Ocean Waves

    Indian Academy of Sciences (India)

    IAS Admin

    (2). Hence, small amplitude waves are also called linear waves. Most of the aspects of the ocean waves can be explained by the small amplitude wave theory. Let us now see the water particle motion due to waves. While wave energy is carried by the wave as it progresses forward, the water particles oscillate up and down.

  7. An alternative way of understanding exit, voice and loyalty: the case of informal payments for health care in Israel.

    Science.gov (United States)

    Cohen, Nissim; Filc, Dani

    2017-01-01

    This study examines Hirschman's model of exit, voice and loyalty with regard to informal payments in the Israeli healthcare system. Based on a national survey, we investigate the extent of "black" payments, its characteristics and its correlated factors. We find that informal payments do exist in Israel-although it seems that there has been a decline in the phenomenon. Contrary to the literature, we find no relationship between the option of voice or dissatisfaction with healthcare services and informal payments. However, we do find a negative correlation between trust and the use of such payments. This finding is consistent with Hirschman's insight that a lack of loyalty may lead people to strategies of exit. We suggest that given the fact that health care in Israel is a public service, the exit option may actually be a quasi-exit behavior. Copyright © 2015 John Wiley & Sons, Ltd. Copyright © 2015 John Wiley & Sons, Ltd.

  8. Shallow Water Waves and Solitary Waves

    OpenAIRE

    Hereman, Willy

    2013-01-01

    Encyclopedic article covering shallow water wave models used in oceanography and atmospheric science. Sections: Definition of the Subject; Introduction and Historical Perspective; Completely Integrable Shallow Water Wave Equations; Shallow Water Wave Equations of Geophysical Fluid Dynamics; Computation of Solitary Wave Solutions; Numerical Methods; Water Wave Experiments and Observations; Future Directions, and Bibliography.

  9. Wave groups in unidirectional surface wave models

    NARCIS (Netherlands)

    van Groesen, Embrecht W.C.

    1998-01-01

    Uni-directional wave models are used to study wave groups that appear in wave tanks of hydrodynamic laboratories; characteristic for waves in such tanks is that the wave length is rather small, comparable to the depth of the layer. In second-order theory, the resulting Nonlinear Schrödinger (NLS)

  10. Stress wave velocity patterns in the longitudinal-radial plane of trees for defect diagnosis

    Science.gov (United States)

    Guanghui Li; Xiang Weng; Xiaocheng Du; Xiping Wang; Hailin Feng

    2016-01-01

    Acoustic tomography for urban tree inspection typically uses stress wave data to reconstruct tomographic images for the trunk cross section using interpolation algorithm. This traditional technique does not take into account the stress wave velocity patterns along tree height. In this study, we proposed an analytical model for the wave velocity in the longitudinal–...

  11. Minimal T-wave representation and its use in the assessment of drug arrhythmogenicity

    DEFF Research Database (Denmark)

    Shakibfar, Saeed; Graff, Claus; Kanters, Jørgen K.

    2017-01-01

    characteristics of the T wave, such as duration, area, amplitude, and slopes. METHODS: In the present work the T wave was down-sampled to a minimal rate, such that a good reconstruction was still possible. The entire T wave was then used as a feature vector to assess drug-induced repolarization effects...

  12. Time-resolved Imaging of H2 + (D2 +) Nuclear Wave Packets

    Science.gov (United States)

    Ergler, Th.; Rudenko, A.; Feuerstein, B.; Zrost, K.; Schröter, C. D.; Moshammer, R.; Ullrich, J.

    The spatio-temporal evolution of H2 + (D2 +) nuclear wave packets is mapped using time-resolved Coulomb explosion imaging. We visualize the motion of both dissociating and bound parts of the wave packet, observe its dephasing and subsequent revivals. The reconstructed probability density of the wave packet is in good agreement with earlier theoretical predictions.

  13. Sar1-GTPase-dependent ER exit of KATP channels revealed by a mutation causing congenital hyperinsulinism

    DEFF Research Database (Denmark)

    Taneja, Tarvinder K; Mankouri, Jamel; Karnik, Rucha

    2009-01-01

    caused by one such mutation in Kir6.2, E282K. The study led to the discovery that Kir6.2 contains a di-acidic ER exit signal, (280)DLE(282), which promotes concentration of the channel into COPII-enriched ER exit sites prior to ER export via a process that requires Sar1-GTPase. The E282K mutation...

  14. Wave Dragon

    DEFF Research Database (Denmark)

    Kramer, Morten; Frigaard, Peter

    På foranledning af Löwenmark F.R.I, er der udført numeriske beregninger af Wave Dragons (herefter WD) armes effektivitet for forskellige geometriske udformninger. 5 geometriske modeller, hvor WD's arme er forkortet/forlænget er undersøgt for 3 forskellige drejninger af armene. I alt er 15...

  15. Voting with their feet: patient exit and intergroup differences in propensity for switching usual source of care.

    Science.gov (United States)

    Tai-Seale, Ming

    2004-06-01

    Many analysts advocate patient exit as a strategy for consumers who experience poor-quality care. Exit is believed to have the potential to improve patient welfare by having patients leave (or "exit") poor-performing health care providers, thus signaling their dissatisfaction with the quality of care they have received and thereby admonishing those providers to improve. However, the validity of exit as a signal of consumer dissatisfaction hinges on how closely it reflects dissatisfaction. Intergroup differences in the propensity to exit could also result in unintended consequences. This article examines the association between consumer experience and the decision to change one's usual care providers. It also investigates if there are any intergroup differences in the propensity for changing providers according to insurance status, gender, and race or ethnicity. Data come from household surveys conducted by the Center for Studying Health System Change. Results show significant intergroup differences in propensity for switching usual source of care for voluntary or involuntary reasons related to insurance, rural residency, age, income, race, and ethnicity. Policy implications of the empirical results on exit, voice, and consumerism are discussed.

  16. Exit blade geometry and part-load performance of small axial flow propeller turbines: An experimental investigation

    Energy Technology Data Exchange (ETDEWEB)

    Singh, Punit; Nestmann, Franz [Institute for Water and River Basin Management (IWG), University of Karlsruhe, Kaiser Str. 12, D 76128 Karlsruhe (Germany)

    2010-09-15

    A detailed experimental investigation of the effects of exit blade geometry on the part-load performance of low-head, axial flow propeller turbines is presented. Even as these turbines find important applications in small-scale energy generation using micro-hydro, the relationship between the layout of blade profile, geometry and turbine performance continues to be poorly characterized. The experimental results presented here help understand the relationship between exit tip angle, discharge through the turbine, shaft power, and efficiency. The modification was implemented on two different propeller runners and it was found that the power and efficiency gains from decreasing the exit tip angle could be explained by a theoretical model presented here based on classical theory of turbomachines. In particular, the focus is on the behaviour of internal parameters like the runner loss coefficient, relative flow angle at exit, mean axial flow velocity and net tangential flow velocity. The study concluded that the effects of exit tip modification were significant. The introspective discussion on the theoretical model's limitation and test facility suggests wider and continued experimentation pertaining to the internal parameters like inlet vortex profile and exit swirl profile. It also recommends thorough validation of the model and its improvement so that it can be made capable for accurate characterization of blade geometric effects. (author)

  17. Coracoclavicular Ligament Reconstruction

    Science.gov (United States)

    Li, Qi; Hsueh, Pei-ling; Chen, Yun-feng

    2014-01-01

    Abstract Operative intervention is recommended for complete acromioclavicular (AC) joint dislocation to restore AC stability, but the best operative technique is still controversial. Twelve fresh-frozen male cadaveric shoulders (average age, 62.8 ± 7.8 years) were equally divided into endobutton versus the modified Weaver-Dunn groups. Each potted scapula and clavicle was fixed in a custom made jig to allow translation and load to failure testing using a Zwick BZ2.5/TS1S material testing machine (Zwick/Roell Co, Germany). A systematic review of 21 studies evaluating reconstructive methods for coracoclavicular or AC joints using a cadaveric model was also performed. From our biomechanical study, after ligament reconstruction, the triple endobutton technique demonstrated superior, anterior, and posterior displacements similar to that of the intact state (P > 0.05). In the modified Weaver-Dunn reconstruction group, however, there was significantly greater anterior (P ligament reconstruction. In addition, there was no significant difference after reconstruction between failure load of the triple endobutton group and that of the intact state (686.88 vs 684.9 N, P > 0.05), whereas the failure load after the modified Weaver-Dunn reconstruction was decreased compared with the intact state (171.64 vs 640.86 N, P ligament is superior to the modified Weaver-Dunn reconstruction in controlling both superior and anteroposterior displacements with a failure load that approximates the intact ligament. PMID:25526435

  18. Utilized friction when entering and exiting a dry and wet bathtub.

    Science.gov (United States)

    Siegmund, Gunter P; Flynn, Jim; Mang, Daniel W; Chimich, Dennis D; Gardiner, John C

    2010-04-01

    Bathtubs and showers are a common source of unintentional slips and falls. The goal of this study was to quantify the friction used by barefoot subjects entering and exiting a typical bathtub/shower enclosure under dry and wet conditions. Sixty subjects (30F, 30M) from three age groups (20-30 years, 40-50 years, 60-70 years) entered and exited a slip-resistant bathtub using six movement patterns (three entering and three exiting the tub) simulating actual use. Force plates installed in the tub floor and the slip-resistant deck outside the tub measured ground reaction forces, from which utilized friction and double support times were calculated. Overall, utilized friction varied from 0.102 to 0.442 (0.235+/-0.057) and was 0.058+/-0.040 lower in wet than dry conditions across all movement patterns (p0.14). Double support times were longer in older subjects than in both young and middle-aged subjects for all movement patterns (p<0.0009) and longer under wet than dry conditions for all entry movements (p<0.0001). These data suggest that subjects regard the wet condition as more hazardous than the dry condition and adapt their utilized friction accordingly. These data also show that older subjects are more cautious than young subjects when confronted with the dual tasks of stepping over the tub's apron and transitioning to a surface perceived to be more slippery. Copyright 2010 Elsevier B.V. All rights reserved.

  19. Exploring Student-to-Workforce Transitions with the National Geoscience Exit Survey

    Science.gov (United States)

    Gonzales, L. M.; Keane, C. M.; Houlton, H. R.

    2011-12-01

    In 2011, the American Geological Institute (AGI) launched the first pilot of a National Geoscience Exit Survey in collaboration with 32 geoscience university departments. The survey collects data about demographics, high school and community college coursework, university degrees, financial aid, field and research experiences, internships, and when and why the student chose to pursue a geosciences degree. Additionally, the survey collects information about students' future academic and career plans, and gives participants the option to take part in a longitudinal survey to track long-term career trajectories of geosciences graduates. The survey also provides geoscience departments with the ability to add customized questions to collect data about important departmental-level topics. The National Geoscience Exit Survey will be available to all U.S. geoscience programs at two- and four-year colleges and universities by the end of the 2011-2012 academic year. We use the results of the National Geoscience Exit Survey to examine student preparation and transition into geosciences and non-geoscience careers. Preliminary results from the pilot survey indicated future academic and career trajectories for geoscience Bachelor's degree recipients included graduate school (53%) and pursuit of a geoscience career (45%), with some undergraduates keeping their options open for either trajectory. Twelve percent of Bachelor's degree recipients already accepted job offers with geoscience employers. For geoscience Master's degree recipients, 17% planned to continue in graduate school, 35% were seeking a geoscience job, and 42% had already accepted job offers with geoscience employers. Furthermore, the majority of those geoscience graduates who already accepted geoscience job offers had also interned previously with the employer.

  20. Plume-exit modeling to determine cloud condensation nuclei activity of aerosols from residential biofuel combustion

    Science.gov (United States)

    Mena, Francisco; Bond, Tami C.; Riemer, Nicole

    2017-08-01

    Residential biofuel combustion is an important source of aerosols and gases in the atmosphere. The change in cloud characteristics due to biofuel burning aerosols is uncertain, in part, due to the uncertainty in the added number of cloud condensation nuclei (CCN) from biofuel burning. We provide estimates of the CCN activity of biofuel burning aerosols by explicitly modeling plume dynamics (coagulation, condensation, chemical reactions, and dilution) in a young biofuel burning plume from emission until plume exit, defined here as the condition when the plume reaches ambient temperature and specific humidity through entrainment. We found that aerosol-scale dynamics affect CCN activity only during the first few seconds of evolution, after which the CCN efficiency reaches a constant value. Homogenizing factors in a plume are co-emission of semi-volatile organic compounds (SVOCs) or emission at small particle sizes; SVOC co-emission can be the main factor determining plume-exit CCN for hydrophobic or small particles. Coagulation limits emission of CCN to about 1016 per kilogram of fuel. Depending on emission factor, particle size, and composition, some of these particles may not activate at low supersaturation (ssat). Hygroscopic Aitken-mode particles can contribute to CCN through self-coagulation but have a small effect on the CCN activity of accumulation-mode particles, regardless of composition differences. Simple models (monodisperse coagulation and average hygroscopicity) can be used to estimate plume-exit CCN within about 20 % if particles are unimodal and have homogeneous composition, or when particles are emitted in the Aitken mode even if they are not homogeneous. On the other hand, if externally mixed particles are emitted in the accumulation mode without SVOCs, an average hygroscopicity overestimates emitted CCN by up to a factor of 2. This work has identified conditions under which particle populations become more homogeneous during plume processes. This

  1. Plume-exit modeling to determine cloud condensation nuclei activity of aerosols from residential biofuel combustion

    Directory of Open Access Journals (Sweden)

    F. Mena

    2017-08-01

    Full Text Available Residential biofuel combustion is an important source of aerosols and gases in the atmosphere. The change in cloud characteristics due to biofuel burning aerosols is uncertain, in part, due to the uncertainty in the added number of cloud condensation nuclei (CCN from biofuel burning. We provide estimates of the CCN activity of biofuel burning aerosols by explicitly modeling plume dynamics (coagulation, condensation, chemical reactions, and dilution in a young biofuel burning plume from emission until plume exit, defined here as the condition when the plume reaches ambient temperature and specific humidity through entrainment. We found that aerosol-scale dynamics affect CCN activity only during the first few seconds of evolution, after which the CCN efficiency reaches a constant value. Homogenizing factors in a plume are co-emission of semi-volatile organic compounds (SVOCs or emission at small particle sizes; SVOC co-emission can be the main factor determining plume-exit CCN for hydrophobic or small particles. Coagulation limits emission of CCN to about 1016 per kilogram of fuel. Depending on emission factor, particle size, and composition, some of these particles may not activate at low supersaturation (ssat. Hygroscopic Aitken-mode particles can contribute to CCN through self-coagulation but have a small effect on the CCN activity of accumulation-mode particles, regardless of composition differences. Simple models (monodisperse coagulation and average hygroscopicity can be used to estimate plume-exit CCN within about 20 % if particles are unimodal and have homogeneous composition, or when particles are emitted in the Aitken mode even if they are not homogeneous. On the other hand, if externally mixed particles are emitted in the accumulation mode without SVOCs, an average hygroscopicity overestimates emitted CCN by up to a factor of 2. This work has identified conditions under which particle populations become more homogeneous during plume

  2. Reconstruction methods for phase-contrast tomography

    Energy Technology Data Exchange (ETDEWEB)

    Raven, C.

    1997-02-01

    Phase contrast imaging with coherent x-rays can be distinguished in outline imaging and holography, depending on the wavelength {lambda}, the object size d and the object-to-detector distance r. When r << d{sup 2}{lambda}, phase contrast occurs only in regions where the refractive index fastly changes, i.e. at interfaces and edges in the sample. With increasing object-to-detector distance we come in the area of holographic imaging. The image contrast outside the shadow region of the object is due to interference of the direct, undiffracted beam and a beam diffracted by the object, or, in terms of holography, the interference of a reference wave with the object wave. Both, outline imaging and holography, offer the possibility to obtain three dimensional information of the sample in conjunction with a tomographic technique. But the data treatment and the kind of information one can obtain from the reconstruction is different.

  3. Exiting RCRA Subtitle C regulation data for supporting a new regulatory path for immobilized mixed debris

    Energy Technology Data Exchange (ETDEWEB)

    Porter, C.L. [Jetseal, Inc., Idaho Falls, ID (United States); Carson, S.D.; Cheng, Wu-Ching [Sandia National Labs., Albuquerque, NM (United States)

    1995-12-31

    This paper presents analytical and empirical data that provide technical support for the position that mixed debris (debris contaminated with both radioactive and hazardous constituents) treated by immobilization in accordance with 40 CFR 268.45 can exit RCRA Subtitle C requirements at the time the treatment is complete. Pathways analyses and risk assessments of low-level waste and RCRA mixed waste disposal facilities show that these two types of facilities provide equivalent long-term (> 100 years) performance and protection of human health and the environment. A proposed two-tier approach for waste form performance criteria is discussed.

  4. Nozzle exit exhaust products from space shuttle boost vehicle (November 1973 design)

    Science.gov (United States)

    1975-01-01

    Principal exhaust species emitted at various altitudes for two trajectories of the space shuttle vehicle are presented. The exhaust composition is given for the nozzle exit plane on the basis of equilibrium chemistry. Afterburning of excess H, H2, and CO in the plume is accounted for. Species considered include HCl and Al2O3, which have been recognized as environmentally significant, as well as others such as H2O (produced by both the solid rocket motor and the orbiter main engine) which, although innocuous, may participate in subsequent chemical reactions in the atmosphere.

  5. Pig characteristics associated with mortality and light exit weight for the nursery phase

    OpenAIRE

    Larriestra, A.J.; Wattanaphansak, S.; Neumann, E.J.; Bradford, J.; Morrison, R B; Van Deen, J.

    2006-01-01

    One thousand and ten weaned pigs that were reared in 1 nursery in Iowa from weaning (17 ± 2 days ) until 10 weeks of age were evaluated. A weaning weight threshold of 3.6 kg maximized the sensitivity and specificity to correctly predict the likelihood of dying or being light in weight at exit from the nursery (≤ 14.5 kg). Weaning weight ≤ 3.6 kg (OR = 2.92), barrow (OR = 1.75), and sow unit (A versus B, OR = 2.14) were significant predictors of mortality in the nursery. Birth weight ≤ 1.0 kg ...

  6. HoReCa-asiakkaiden tuotteen x asiakassuhteen exit-haastattelut

    OpenAIRE

    Rokkonen, Saara

    2011-01-01

    Uusien asiakkaiden hankkiminen tulee yrityksille kalliimmaksi kuin vanhojen asiakkaiden pi-täminen. Jo tästä syystä yritysten kannattaa pitää vanhat asiakkaat tyytyväisinä ja panostaa heille tarjoamiinsa tuotteisiin ja palveluihin kokonaisvaltaisesti. Useissa yrityksissä tutkitaan vuosittain asiakastyytyväisyyttä erilaisilla menetelmillä ja mittareilla. Harvoin kukaan kuitenkaan kiinnittää huomiota jo menetettyihin asiakkaisiin ja lähdön syihin. Exit-haastatteluista saatavan tiedon avulla voi...

  7. An annular gas seal analysis using empirical entrance and exit region friction factors

    Science.gov (United States)

    Elrod, D. A.; Childs, D. W.; Nelson, C. C.

    1990-01-01

    Wall shear stress results from stationary-rotor flow tests of five annular gas seals are used to develop entrance and exit region friction factor models. The friction factor models are used in a bulk-flow seal analysis which predicts leakage and rotor-dynamic coefficients. The predictions of the analysis are compared to experimental results and to the predictions of Nelson's analysis (1985). The comparisons are for smooth-rotor seals with smooth and honeycomb-stators. The present analysis predicts the destabilizing cross-coupled stiffness of a seal better than Nelson's analysis. Both analyses predict direct damping well and direct stiffness poorly.

  8. Delayed breast implant reconstruction

    DEFF Research Database (Denmark)

    Hvilsom, Gitte B.; Hölmich, Lisbet R.; Steding-Jessen, Marianne

    2011-01-01

    Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed breast reconstruction separately for one- and two-stage pro......Studies of complications following reconstructive surgery with implants among women with breast cancer are needed. As the, to our knowledge, first prospective long-term study we evaluated the occurrence of complications following delayed breast reconstruction separately for one- and two......-stage procedures. From the Danish Registry for Plastic Surgery of the Breast, which has prospectively registered data for women undergoing breast implantations since 1999, we identified 559 women without a history of radiation therapy undergoing 592 delayed breast reconstructions following breast cancer during...... the period 1999 to 2006; 239 one-stage procedures and 353 two-stage procedures. The postoperative course through November 2009 was evaluated by cumulative incidence adjusting for competing risks for the selected outcomes; hematoma, infection, seroma, implant rupture, severe capsular contracture (modified...

  9. Permutationally invariant state reconstruction

    DEFF Research Database (Denmark)

    Moroder, Tobias; Hyllus, Philipp; Tóth, Géza

    2012-01-01

    Feasible tomography schemes for large particle numbers must possess, besides an appropriate data acquisition protocol, an efficient way to reconstruct the density operator from the observed finite data set. Since state reconstruction typically requires the solution of a nonlinear large-scale opti...... optimization, which has clear advantages regarding speed, control and accuracy in comparison to commonly employed numerical routines. First prototype implementations easily allow reconstruction of a state of 20 qubits in a few minutes on a standard computer.......-scale optimization problem, this is a major challenge in the design of scalable tomography schemes. Here we present an efficient state reconstruction scheme for permutationally invariant quantum state tomography. It works for all common state-of-the-art reconstruction principles, including, in particular, maximum...... likelihood and least squares methods, which are the preferred choices in today's experiments. This high efficiency is achieved by greatly reducing the dimensionality of the problem employing a particular representation of permutationally invariant states known from spin coupling combined with convex...

  10. Gravitational waves

    CERN Document Server

    Ciufolini, I; Moschella, U; Fre, P

    2001-01-01

    Gravitational waves (GWs) are a hot topic and promise to play a central role in astrophysics, cosmology, and theoretical physics. Technological developments have led us to the brink of their direct observation, which could become a reality in the coming years. The direct observation of GWs will open an entirely new field: GW astronomy. This is expected to bring a revolution in our knowledge of the universe by allowing the observation of previously unseen phenomena, such as the coalescence of compact objects (neutron stars and black holes), the fall of stars into supermassive black holes, stellar core collapses, big-bang relics, and the new and unexpected.With a wide range of contributions by leading scientists in the field, Gravitational Waves covers topics such as the basics of GWs, various advanced topics, GW detectors, astrophysics of GW sources, numerical applications, and several recent theoretical developments. The material is written at a level suitable for postgraduate students entering the field.

  11. Wave Star

    DEFF Research Database (Denmark)

    Kramer, Morten; Frigaard, Peter; Brorsen, Michael

    Nærværende rapport beskriver foreløbige hovedkonklusioner på modelforsøg udført på Aalborg Universitet, Institut for Vand, Jord og Miljøteknik med bølgeenergianlægget Wave Star i perioden 13/9 2004 til 12/11 2004.......Nærværende rapport beskriver foreløbige hovedkonklusioner på modelforsøg udført på Aalborg Universitet, Institut for Vand, Jord og Miljøteknik med bølgeenergianlægget Wave Star i perioden 13/9 2004 til 12/11 2004....

  12. Wave Propagation

    CERN Document Server

    Ferrarese, Giorgio

    2011-01-01

    Lectures: A. Jeffrey: Lectures on nonlinear wave propagation.- Y. Choquet-Bruhat: Ondes asymptotiques.- G. Boillat: Urti.- Seminars: D. Graffi: Sulla teoria dell'ottica non-lineare.- G. Grioli: Sulla propagazione del calore nei mezzi continui.- T. Manacorda: Onde nei solidi con vincoli interni.- T. Ruggeri: "Entropy principle" and main field for a non linear covariant system.- B. Straughan: Singular surfaces in dipolar materials and possible consequences for continuum mechanics

  13. Shock Waves

    CERN Document Server

    Jiang, Z

    2005-01-01

    The International Symposium on Shock Waves (ISSW) is a well established series of conferences held every two years in a different location. A unique feature of the ISSW is the emphasis on bridging the gap between physicists and engineers working in fields as different as gas dynamics, fluid mechanics and materials sciences. The main results presented at these meetings constitute valuable proceedings that offer anyone working in this field an authoritative and comprehensive source of reference.

  14. Arctic Sea Level Reconstruction

    DEFF Research Database (Denmark)

    Svendsen, Peter Limkilde

    gauge record and makes the reconstruction much less prone to drifting away over time.Unfortunately, many of the Russian-sector tide gauge records end around 1990,leaving a fairly sparse record after this. This project examines the effect of introducing a subset of the altimetric dataset as “virtual tide......Reconstruction of historical Arctic sea level is very difficult due to the limited coverage and quality of tide gauge and altimetry data in the area. This thesis addresses many of these issues, and discusses strategies to help achieve a stable and plausible reconstruction of Arctic sea level from...... 1950 to today.The primary record of historical sea level, on the order of several decades to a few centuries, is tide gauges. Tide gauge records from around the world are collected in the Permanent Service for Mean Sea Level (PSMSL) database, and includes data along the Arctic coasts. A reasonable...

  15. Detonation wave parameters in a variable cross section channel in gas mixture of methane with oxygen and nitrogen

    OpenAIRE

    G. Y. Bivol; V. S. Golovastov; A. Yu. Mikushkin

    2014-01-01

    Propagation of the detonation wave in gas mixtures of methane with oxygen in a channel of variable cross section was studied experimentally. To conduct these investigations a special detonation combustion chamber comprising sections of various diameters has been designed. In the section of detonation wave formation a combustible mixture was ignited. After that, a flame front accelerated till the formation of detonation. At the exit from the combustion chamber there was an outlet conical secti...

  16. Iterative initial condition reconstruction

    Science.gov (United States)

    Schmittfull, Marcel; Baldauf, Tobias; Zaldarriaga, Matias

    2017-07-01

    Motivated by recent developments in perturbative calculations of the nonlinear evolution of large-scale structure, we present an iterative algorithm to reconstruct the initial conditions in a given volume starting from the dark matter distribution in real space. In our algorithm, objects are first moved back iteratively along estimated potential gradients, with a progressively reduced smoothing scale, until a nearly uniform catalog is obtained. The linear initial density is then estimated as the divergence of the cumulative displacement, with an optional second-order correction. This algorithm should undo nonlinear effects up to one-loop order, including the higher-order infrared resummation piece. We test the method using dark matter simulations in real space. At redshift z =0 , we find that after eight iterations the reconstructed density is more than 95% correlated with the initial density at k ≤0.35 h Mpc-1 . The reconstruction also reduces the power in the difference between reconstructed and initial fields by more than 2 orders of magnitude at k ≤0.2 h Mpc-1 , and it extends the range of scales where the full broadband shape of the power spectrum matches linear theory by a factor of 2-3. As a specific application, we consider measurements of the baryonic acoustic oscillation (BAO) scale that can be improved by reducing the degradation effects of large-scale flows. In our idealized dark matter simulations, the method improves the BAO signal-to-noise ratio by a factor of 2.7 at z =0 and by a factor of 2.5 at z =0.6 , improving standard BAO reconstruction by 70% at z =0 and 30% at z =0.6 , and matching the optimal BAO signal and signal-to-noise ratio of the linear density in the same volume. For BAO, the iterative nature of the reconstruction is the most important aspect.

  17. Vertex Reconstruction in CMS

    CERN Document Server

    Chabanat, E; D'Hondt, J; Vanlaer, P; Prokofiev, K; Speer, T; Frühwirth, R; Waltenberger, W

    2005-01-01

    Because of the high track multiplicity in the final states expected in proton collisions at the LHC experiments, novel vertex reconstruction algorithms are required. The vertex reconstruction problem can be decomposed into a pattern recognition problem ("vertex finding") and an estimation problem ("vertex fitting"). Starting from least-square methods, ways to render the classical algorithms more robust are discussed and the statistical properties of the novel methods are shown. A whole set of different approaches for the vertex finding problem is presented and compared in relevant physics channels.

  18. Role for non-proteolytic control of M-phase-promoting factor activity at M-phase exit.

    Directory of Open Access Journals (Sweden)

    Vincenzo D'Angiolella

    Full Text Available M-phase Promoting Factor (MPF; the cyclin B-cdk 1 complex is activated at M-phase onset by removal of inhibitory phosphorylation of cdk1 at thr-14 and tyr-15. At M-phase exit, MPF is destroyed by ubiquitin-dependent cyclin proteolysis. Thus, control of MPF activity via inhibitory phosphorylation is believed to be particularly crucial in regulating transition into, rather than out of, M-phase. Using the in vitro cell cycle system derived form Xenopus eggs, here we show, however, that inhibitory phosphorylation of cdk1 contributes to control MPF activity during M-phase exit. By sampling extracts at very short intervals during both meiotic and mitotic exit, we found that cyclin B1-associated cdk1 underwent transient inhibitory phosphorylation at tyr-15 and that cyclin B1-cdk1 activity fell more rapidly than the cyclin B1 content. Inhibitory phosphorylation of MPF correlated with phosphorylation changes of cdc25C, the MPF phosphatase, and physical interaction of cdk1 with wee1, the MPF kinase, during M-phase exit. MPF down-regulation required Ca(++/calmodulin-dependent kinase II (CaMKII and cAMP-dependent protein kinase (PKA activities at meiosis and mitosis exit, respectively. Treatment of M-phase extracts with a mutant cyclin B1-cdk1AF complex, refractory to inhibition by phosphorylation, impaired binding of the Anaphase Promoting Complex/Cyclosome (APC/C to its co-activator Cdc20 and altered M-phase exit. Thus, timely M-phase exit requires a tight coupling of proteolysis-dependent and proteolysis-independent mechanisms of MPF inactivation.

  19. Indirect costs associated with early exit from work attributable to rheumatic diseases.

    Science.gov (United States)

    Laires, Pedro A; Canhão, Helena; Gouveia, Miguel

    2015-08-01

    Rheumatic diseases (RD) cause physical disability that may lead to early exit from work, generating indirect costs to society. We aimed to measure these costs in a population approaching the statutory retirement age. The analysis was based on the prevalence of self-reported RD using a bottom-up approach. Health and sociodemographic data were retrieved from the fourth National Health Survey (INS), for all people between 50 and 64 years of age (3762 men and 4241 women), whereas an official national database was used to estimate productivity values by gender, age group and region, using the human capital approach. The effects of RD on the likelihood of early exit from paid employment and the attributable fractions estimates were obtained at the individual level by logistic regression. At the time of the survey, 37.2% of the population aged 50-64 years self-reported at least one RD. Among these, 52.6% were not employed, compared with 40.7% of those without RD (P GDP. The public health concern and the economic impact highlight the need to prioritize investments in health and social protection policies targeting patients with rheumatic conditions. © The Author 2015. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  20. Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit.

    Science.gov (United States)

    Puvvula, Pavan Kumar; Desetty, Rohini Devi; Pineau, Pascal; Marchio, Agnés; Moon, Anne; Dejean, Anne; Bischof, Oliver

    2014-11-19

    Cellular senescence is a stable cell cycle arrest that limits the proliferation of pre-cancerous cells. Here we demonstrate that scaffold-attachment-factor A (SAFA) and the long noncoding RNA PANDA differentially interact with polycomb repressive complexes (PRC1 and PRC2) and the transcription factor NF-YA to either promote or suppress senescence. In proliferating cells, SAFA and PANDA recruit PRC complexes to repress the transcription of senescence-promoting genes. Conversely, the loss of SAFA-PANDA-PRC interactions allows expression of the senescence programme. Accordingly, we find that depleting either SAFA or PANDA in proliferating cells induces senescence. However, in senescent cells where PANDA sequesters transcription factor NF-YA and limits the expression of NF-YA-E2F-coregulated proliferation-promoting genes, PANDA depletion leads to an exit from senescence. Together, our results demonstrate that PANDA confines cells to their existing proliferative state and that modulating its level of expression can cause entry or exit from senescence.

  1. EXITE/IPC observations of SN1987A and southern targets

    Science.gov (United States)

    Grindlay, Jonathan E.

    1991-01-01

    The Energetic X-ray Imaging Telescope Experiment (EXITE) was developed to a flight-ready status and conducted two flights (May 18, 1988, and May 8-10, 1989) from Alice Springs, Australia, as part of the campaigns to observe the supernova SN1987A. The basic operation of the detector and gondola systems in the laboratory was tested on the first flight and found to meet expected performance values. A bizarre 'balloon tape' insulation problem, however, prevented normal telescope pointing on the first flight so no data on SN1987A or other targets were obtained. Following a successful second EXITE flight from Ft. Sumner, NM, in October 1988, the experiment was flown again on a successful 30 hour flight as part of the final 1989 supernova campaign. A second x-ray imaging experiment from MSFC was also flown (piggy-back) for this third flight. Good data were obtained on the supernova and a variety of high priority galactic targets, and final analysis is still in progress. Preliminary results from this flight are presented.

  2. Eternal extended inflation and graceful exit from old inflation without Jordan-Brans-Dicke

    Science.gov (United States)

    Linde, Andrei

    1990-10-01

    Recently a possible solution to the graceful exit problem of the old inflation was proposed in the context of the Jordan-Brans-Dicke theory (extended inflation). In this paper we will argue that inflation in this theory occurs in a most natural way if it starts near the Planck density, as in the standard version of chaotic inflation. With most natural initial conditions, the inflationary universe in the JBD theory enters the stage of permanent reproduction of new inflationary domains (eternal extended inflation). In order to realize the extended inflation scenario at least two classical scalar fields driving inflation are necessary, as distinct from the simplest versions of new and chaotic inflation. It is shown that in the theory of two scalar fields one can solve the graceful exit problem even without modifying the Einstein gravity theory, due to the possibility that the decay rate of the false rate vacuum in old inflation depends on the value of the second scalar field and hence on time. Address after 1 September 1990: Physics Department, Stanford University, Varian Building, Stanford, CA 94305, USA.

  3. Diabetes associated with early labor-force exit: a comparison of sixteen high-income countries.

    Science.gov (United States)

    Rumball-Smith, Juliet; Barthold, Douglas; Nandi, Arijit; Heymann, Jody

    2014-01-01

    The economic burden of diabetes and the effects of the disease on the labor force are of substantial importance to policy makers. We examined the impact of diabetes on leaving the labor force across sixteen countries, using data about 66,542 participants in the Survey of Health, Ageing and Retirement in Europe; the US Health and Retirement Survey; or the English Longitudinal Study of Ageing. After matching people with diabetes to those without the disease in terms of age, sex, and years of education, we used Cox proportional hazards analyses to estimate the effect of diabetes on time of leaving the labor force. Across the sixteen countries, people diagnosed with diabetes had a 30 percent increase in the rate of labor-force exit, compared to people without the disease. The costs associated with earlier labor-force exit are likely to be substantial. These findings further support the value of greater public- and private-sector investment in preventing and managing diabetes.

  4. Pulsed laser Rayleigh scattering diagnostic for hydrogen/oxygen rocket exit plane flowfield velocimetry

    Science.gov (United States)

    Zupanc, Frank J.

    1993-01-01

    A Doppler-resolved, pulsed laser Rayleigh scattering diagnostic has been developed to obtain local flowfield velocity measurements at the exit plane of a low thrust hydrogen/oxygen rocket engine operating in a high-altitude test facility. Fiberoptic signal collection was employed to obtain the forescatter and backscatter Doppler shifts necessary to resolve the axial and radial velocity components. A radial profile was obtained by traversing the collection probes along the beam path at the nozzle exit. The results are compared with theoretical predictions from a full Navier-Stokes model (RK/RPLUS). Significant discrepancies between the measured and predicted axial velocity profiles are observed, in terms of both magnitude and character. Radial velocity measurements exhibit excellent agreement with predictions near the centerline but show some departure off-axis. The discrepancies between theory and experiment are potentially the result of enhanced mixing between the core and fuel-film region beyond that predicted, and/or flow stratification between the hydrogen and oxygen injected into the central core region.

  5. PP1-mediated moesin dephosphorylation couples polar relaxation to mitotic exit.

    Science.gov (United States)

    Kunda, Patricia; Rodrigues, Nelio T L; Moeendarbary, Emadaldin; Liu, Tao; Ivetic, Aleksandar; Charras, Guillaume; Baum, Buzz

    2012-02-07

    Animal cells undergo dramatic actin-dependent changes in shape as they progress through mitosis; they round up upon mitotic entry and elongate during chromosome segregation before dividing into two [1-3]. Moesin, the sole Drosophila ERM-family protein [4], plays a critical role in this process, through the construction of a stiff, rounded metaphase cortex [5-7]. At mitotic exit, this rigid cortex must be dismantled to allow for anaphase elongation and cytokinesis through the loss of the active pool of phospho-Thr559moesin from cell poles. Here, in an RNA interference (RNAi) screen for phosphatases involved in the temporal and spatial control of moesin, we identify PP1-87B RNAi as having elevated p-moesin levels and reduced cortical compliance. In mitosis, RNAi-induced depletion of PP1-87B or depletion of a conserved noncatalytic PP1 phosphatase subunit Sds22 leads to defects in p-moesin clearance from cell poles at anaphase, a delay in anaphase elongation, together with defects in bipolar anaphase relaxation and cytokinesis. Importantly, similar cortical defects are seen at anaphase following the expression of a constitutively active, phosphomimetic version of moesin. These data reveal a new role for the PP1-87B/Sds22 phosphatase, an important regulator of the metaphase-anaphase transition, in coupling moesin-dependent cell shape changes to mitotic exit. Copyright © 2012 Elsevier Ltd. All rights reserved.

  6. Men Who Stop Caring: The Exit of Men from Caring Occupations

    Directory of Open Access Journals (Sweden)

    Kenn Warming

    2013-12-01

    Full Text Available In recent years, initiatives have been taken to attract more men into caring occupations. However, there has been much less focus on retaining these new male workers. This article builds on qualitative interviews with 11 Danish men who after working in the caring sector decided to leave for other occupations. A factor often presented as influential for the men’s exit concerns the social working environment. In the interviews, the men discuss the pressure to assimilate to the existing and established female-dominated culture. They feel excluded and socially isolated. Several of them have been directly criticized or disqualified as not being “real” men by their female colleagues. As a result of a growing bureaucratic demand for control and registration of work procedures, several men feel that they do not have adequate resources and time to provide the level of care that is needed. They become disillusioned and frustrated and choose to seek employment elsewhere. Some men cannot come to terms with close physical contact and “smells,” for example, changing diapers on infants or bathing old people. They cannot handle the thought of having their intentions misinterpreted, for example, when playing and being physical with children, and being potentially seen as sexually abhorrent. Finally, some men never intended to remain permanently in caring occupations. Their exit is driven by an ambition to pursue a career in another field or at what they view as a more challenging career level.

  7. Molecular Signaling Involved in Entry and Exit of Malaria Parasites from Host Erythrocytes.

    Science.gov (United States)

    Singh, Shailja; Chitnis, Chetan E

    2017-10-03

    During the blood stage, Plasmodium spp. merozoites invade host red blood cells (RBCs), multiply, exit, and reinvade uninfected RBCs in a continuing cycle that is responsible for all the clinical symptoms associated with malaria. Entry into (invasion) and exit from (egress) RBCs are highly regulated processes that are mediated by an array of parasite proteins with specific functional roles. Many of these parasite proteins are stored in specialized apical secretory vesicles, and their timely release is critical for successful invasion and egress. For example, the discharge of parasite protein ligands to the apical surface of merozoites is required for interaction with host receptors to mediate invasion, and the timely discharge of proteases and pore-forming proteins helps in permeabilization and dismantling of limiting membranes during egress. This review focuses on our understanding of the signaling mechanisms that regulate apical organelle secretion during host cell invasion and egress by malaria parasites. The review also explores how understanding key signaling mechanisms in the parasite can open opportunities to develop novel strategies to target Plasmodium parasites and eliminate malaria. Copyright © 2017 Cold Spring Harbor Laboratory Press; all rights reserved.

  8. “Thanks for Using Me”: An Exploration of Exit Strategy in Qualitative Research

    Directory of Open Access Journals (Sweden)

    Zachary James Morrison MSc

    2012-09-01

    Full Text Available This article examines, through a synthesis of the literature and excerpts from a qualitative case study, the concept of exit strategy, specifically its relation to vulnerable populations (e.g., overweight adolescent boys and potential impact on the researcher-participant relationship. The quality and duration of the researcher-participant relationship, along with rapport and trust building, are potential indicators for negotiated closure (i.e., exit strategy. Reframing this relationship as “participant-researcher” resituates vulnerable participants as foremost in such relationships. Given what is potentially at stake for participants in qualitative research, there is a moral and ethical imperative to enter into the dialogue of closure. Otherwise, participants may unwittingly serve as a means to an end, that is, as objects in the enterprise of qualitative research. Researchers, research supervisors, and human subject ethics committees are urged to establish protocols to guide how research relationships are ended within the context of qualitative methods, particularly with respect to vulnerable populations.

  9. Structure of the Cyanuric Acid Hydrolase TrzD Reveals Product Exit Channel

    Energy Technology Data Exchange (ETDEWEB)

    Bera, Asim K; Aukema, Kelly G.; Elias, Mikael; Wackett, Lawrence P. (UMM)

    2017-03-27

    Cyanuric acid hydrolases are of industrial importance because of their use in aquatic recreational facilities to remove cyanuric acid, a stabilizer for the chlorine. Degradation of excess cyanuric acid is necessary to maintain chlorine disinfection in the waters. Cyanuric acid hydrolase opens the cyanuric acid ring hydrolytically and subsequent decarboxylation produces carbon dioxide and biuret. In the present study, we report the X-ray structure of TrzD, a cyanuric acid hydrolase from Acidovorax citrulli. The crystal structure at 2.19 Å resolution shows a large displacement of the catalytic lysine (Lys163) in domain 2 away from the active site core, whereas the two other active site lysines from the two other domains are not able to move. The lysine displacement is proposed here to open up a channel for product release. Consistent with that, the structure also showed two molecules of the co-product, carbon dioxide, one in the active site and another trapped in the proposed exit channel. Previous data indicated that the domain 2 lysine residue plays a role in activating an adjacent serine residue carrying out nucleophilic attack, opening the cyanuric acid ring, and the mobile lysine guides products through the exit channel.

  10. Nozzle Exit Over-Pressure and Vortex Ring Interaction in a Fully-Pulsed Jet

    Science.gov (United States)

    Krueger, Paul S.; Gharib, Morteza

    2002-11-01

    Vortex rings formed by a starting jets will stop entraining circulation and pinch off from their generating or "trailing" jet for sufficiently large piston stroke length to jet diameter ratios (L/D) [Gharib et. al., JFM, 1998]. Recent work by the authors has demonstrated that the leading vortex ring contributes more impulse per unit L/D than does the trailing jet, highlighting the significance of vortex ring pinch off for propulsive applications. The impulse advantage of the leading vortex ring is provided by nozzle exit over-pressure resulting from the acceleration of ambient fluid during ring formation. The present work extends these single-pulse results to a periodic series of starting jets, i.e., a fully-pulsed jet. Measurements were made of the time-averaged thrust of fully-pulsed jets generated using a piston-cylinder mechanism for 2 < L/D < 6 and a range of pulsing frequencies. The results indicate that vortex ring formation provides substantial nozzle exit over-pressure (and hence, thrust benefit) in the pulsed case as well, but the benefit tends to diminish with increasing frequency. Various vortex ring interactions contribute to this trend.

  11. Letting go: How newly graduated registered nurses in Western Canada decide to exit the nursing profession.

    Science.gov (United States)

    Chachula, Kathryn M; Myrick, Florence; Yonge, Olive

    2015-07-01

    The Canadian Nurses Association (CNA) estimates a nursing shortage in Canada will rise to 60,000 registered nurses by 2022. Further compounding this crisis is the approximate 14-61% of new nursing graduates who will change nursing roles or exit the profession. To explore the factors and basic psychosocial process involved in the decisions of newly graduated registered nurses in Western Canada who permanently exit the nursing profession within five years. Data was collected through unstructured and semi-structured interviews using the Glaserian grounded theory method. Participants were found to be in a process of letting go of nursing that commenced as students and continued as they entered practice as registered nurses. Four major themes were identified. 1) Navigating constraints of the healthcare system and workplace: participants encountered difficulties adjusting to shiftwork and workload. 2) Negotiating social relationships, hierarchies, and troublesome behaviors; specifically hierarchal and horizontal violence. 3) Facing fears, traumas and challenges. 4) Weighing competing rewards and tensions which resulted in leaving the nursing profession. Students and subsequently new nursing graduates require a variety of supports to establish a nursing identity and remain in the profession. These supports include a manageable workload; meaningful orientation; interprofessional teamwork; and engagement within transformational and authentic leadership constructs. New nurses require a sense of being welcomed, valued, respected and accepted into the workplace environment, as well as constructive feedback, emotional support and debriefing to face workplace challenges. Copyright © 2015 Elsevier Ltd. All rights reserved.

  12. Exploring life expectancy limits: First exit time modeling, parameter analysis and forecasts

    Science.gov (United States)

    Skiadas, Christos H.; Skiadas, Charilaos

    In this paper we explore the life expectancy limits by based on the stochastic modeling of mortality and applying the first exit or hitting time theory of a stochastic process. The main assumption is that the health state or the "vitality", according to Strehler and Mildvan, of an individual is a stochastic variable and thus it was introduced and applied a first exit time density function to mortality data. The model is used to estimate the development of mortality rates in the late stages of the human life span, to make better fitting to population mortality data including the infant mortality, to compare it with the classical Gompertz curve, and to make comparisons between the Carey medfly data and the population mortality data estimating the health state or "vitality" functions. Furthermore, we apply the model to the life table data of Italy, France, USA, Canada, Sweden, Norway and Japan, and we analyze the characteristic parameters of the model and make forecasts. The case of female mortality in Sweden is extensively studied and forecasts to 2025 and 2050 are presented.

  13. A preliminary study of mental and physical practice on the kayak wet exit skill.

    Science.gov (United States)

    Millard, M; Mahoney, C; Wardrop, J

    2001-06-01

    Outdoor activities and high-risk water sports often create anxiety in participants who feel concern about danger. Relaxation and imagery, often used to enhance training, can improve performance of skills in a variety of sports. The aim of this study was to establish whether Mental Practice, Physical Practice, Combined Mental and Physical Practice, or No Practice would affect the acquisition of skill for a kayak wet exit. 60 postprimary girls aged 11-16 yr., competent swimmers but without previous experience in kayaking, gave their informed consent to be in the study. Each participant was randomly assigned to one of the four experimental groups. Following their practice periods, each group performed three kayak wet exit attempts (unseen by others); these were videotaped for later analysis by an observer. The participant and an independent observer, who was blind to the allocation of practice group, then used a 6-point rating scale to assess each performance. Participants' and the observer's ratings were analysed by separate Kruskal-Wallis one-way analysis of variance which indicated a significant practice effect. Subsequent chi-squared tests indicated significantly different distributions of groups, showing Physical Practice superior to No Practice and Mental Practice. While physical practice remained effective in improving technique, combinations of mental and physical practice were better than no practice.

  14. Reconstruction of Peripelvic Oncologic Defects.

    Science.gov (United States)

    Weichman, Katie E; Matros, Evan; Disa, Joseph J

    2017-10-01

    After studying this article, the participant should be able to: 1. Understand the anatomy of the peripelvic area. 2. Understand the advantages and disadvantages of performing peripelvic reconstruction in patients undergoing oncologic resection. 3. Select the appropriate local, pedicled, or free-flap reconstruction based on the location of the defect and donor-site characteristics. Peripelvic reconstruction most commonly occurs in the setting of oncologic ablative surgery. The peripelvic area contains several distinct reconstructive regions, including vagina, vulva, penis, and scrotum. Each area provides unique reconstructive considerations. In addition, prior or future radiation therapy or chemotherapy along with cancer cachexia can increase the complexity of reconstruction.

  15. REFLECTION OF ELECTROMAGNETIC WAVES FROM SOUND WAVES

    Science.gov (United States)

    The reflection of electromagnetic waves normally incident on the wavefronts of a semi-infinite standing sound wave is discussed. By analogy with the...with the sound frequency. An experiment is described in which the Bragg reflection of 3 cm electromagnetic waves from a standing sound wave beneath a water surface is observed.

  16. Impact of Wave Dragon on Wave Climate

    DEFF Research Database (Denmark)

    Andersen, Thomas Lykke; Tedd, James; Kramer, Morten

    This report is an advisory paper for use in determining the wave dragon effects on hydrography, by considering the effect on the wave climate in the region of a wave dragon. This is to be used in the impact assessment for the Wave Dragon pre-commercial demonstrator....

  17. Can favourable psychosocial working conditions in midlife moderate the risk of work exit for chronically ill workers? A 20-year follow-up of the Whitehall II study.

    Science.gov (United States)

    Fleischmann, Maria; Carr, Ewan; Stansfeld, Stephen A; Xue, Baowen; Head, Jenny

    2017-10-17

    To investigate if favourable psychosocial working conditions can reduce the risk of work exit and specifically for workers with chronic disease. Men and women (32%) aged 35-55, working and having no chronic disease at baseline of the Whitehall II study of London-based civil servants were selected (n=9040). We observed participants' exit from work through retirement, health-related exit and unemployment, new diagnosis of chronic disease (ie, coronary heart disease, diabetes, stroke and cancer) and their psychosocial working conditions in midlife. Using cause-specific Cox models, we examined the association of chronic disease and favourable psychosocial working conditions and their interaction, with the three types of work exit. We adjusted for gender, occupational grade, educational level, remaining in civil service, spouse's employment status and mental health. Chronic disease significantly increased the risk of any type of work exit (HR 1.27) and specifically the risk of health-related exit (HR 2.42). High skill discretion in midlife reduced the risk of any type of work exit (HR 0.90), retirement (HR 0.91) and health-related exit (HR 0.68). High work social support in midlife decreased the risk of health-related exit (HR 0.79) and unemployment (HR 0.71). Favourable psychosocial working conditions in midlife did not attenuate the association between chronic disease and work exit significantly. The chronically ill have increased risks of work exit, especially through health-related exit routes. Chronic disease is an obstacle to extended working lives. Favourable working conditions directly relate to reduced risks of work exit. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

  18. Evolution of blast wave profiles in simulated air blasts: experiment and computational modeling

    Science.gov (United States)

    Chandra, N.; Ganpule, S.; Kleinschmit, N. N.; Feng, R.; Holmberg, A. D.; Sundaramurthy, A.; Selvan, V.; Alai, A.

    2012-09-01

    Shock tubes have been extensively used in the study of blast traumatic brain injury due to increased incidence of blast-induced neurotrauma in Iraq and Afghanistan conflicts. One of the important aspects in these studies is how to best replicate the field conditions in the laboratory which relies on reproducing blast wave profiles. Evolution of the blast wave profiles along the length of the compression-driven air shock tube is studied using experiments and numerical simulations with emphasis on the shape and magnitude of pressure time profiles. In order to measure dynamic pressures of the blast, a series of sensors are mounted on a cylindrical specimen normal to the flow direction. Our results indicate that the blast wave loading is significantly different for locations inside and outside of the shock tube. Pressure profiles inside the shock tube follow the Friedlander waveform fairly well. Upon approaching exit of the shock tube, an expansion wave released from the shock tube edges significantly degrades the pressure profiles. For tests outside the shock tube, peak pressure and total impulse reduce drastically as we move away from the exit and majority of loading is in the form of subsonic jet wind. In addition, the planarity of the blast wave degrades as blast wave evolves three dimensionally. Numerical results visually and quantitatively confirm the presence of vortices, jet wind and three-dimensional expansion of the planar blast wave near the exit. Pressure profiles at 90° orientation show flow separation. When cylinder is placed inside, this flow separation is not sustained, but when placed outside the shock tube this flow separation is sustained which causes tensile loading on the sides of the cylinder. Friedlander waves formed due to field explosives in the intermediate-to far-field ranges are replicated in a narrow test region located deep inside the shock tube.

  19. On the analytical solution of the S{sub N} equation in a rectangle assuming an exponential exiting angular flux boundary

    Energy Technology Data Exchange (ETDEWEB)

    Goncalez, Tifani T. [Universidade Federal do Rio Grande do Sul (PROMEC/UFRGS), Porto Alegre, RS (Brazil). Programa de Pos-Graduacao em Engenharia Mecanica; Segatto, Cynthia F.; Vilhena, Marco Tullio, E-mail: csegatto@pq.cnpq.b, E-mail: vilhena@pq.cnpq.b [Universidade Federal do Rio Grande do Sul (DMPA/UFRGS), Porto Alegre, RS (Brazil). Programa de Pos-Graduacao em Matematica Aplicada

    2011-07-01

    In this work, we report an analytical solution for the set of S{sub N} equations for the angular flux, in a rectangle, using the double Laplace transform technique. Its main idea comprehends the steps: application of the Laplace transform in one space variable, solution of the resulting equation by the LTS{sub N} method and reconstruction of the double Laplace transformed angular flux using the inversion theorem of the Laplace transform. We must emphasize that we perform the Laplace inversion by the LTS{sub N} method in the x direction, meanwhile we evaluate the inversion in the y direction performing the calculation of the corresponding line integral solution by the Stefest method. We have also to figure out that the application of Laplace transform to this type of boundary value problem introduces additional unknown functions associated to the partial derivatives of the angular flux at boundary. Based on the good results attained by the nodal LTS{sub N} method, we assume that the angular flux at boundary is also approximated by an exponential function. By analytical we mean that no approximation is done along the solution derivation except for the exponential hypothesis for the exiting angular flux at boundary. For sake of completeness, we report numerical comparisons of the obtained results against the ones of the literature. (author)

  20. Craniofacial reconstruction - slideshow

    Science.gov (United States)

    ... GO GO About MedlinePlus Site Map FAQs Customer Support Health Topics Drugs & Supplements Videos & Tools Español You Are Here: Home → Medical Encyclopedia → Craniofacial reconstruction - series—Normal anatomy URL of this page: //medlineplus.gov/ency/presentations/ ...

  1. Reconstructing Community History

    Science.gov (United States)

    Shields, Amy

    2004-01-01

    History is alive and well in Lebanon, Missouri. Students in this small town in the southwest region of the state went above and beyond the community's expectations on this special project. This article describes this historical journey which began when students in a summer mural class reconstructed a mural that was originally created by a…

  2. 'grass roots' reconstructive action

    African Journals Online (AJOL)

    The paper discusses a two year action research investigation of conceptual, evaluation and adoption tensions that led to a revised approach to environmental ... a sustained dialogue around the prevailing science curriculum, local environmental issues and everyday classroom activities fostered reconstructive change at a ...

  3. Urogenital Reconstructive Surgery

    DEFF Research Database (Denmark)

    Jakobsen, Lotte Kaasgaard

    Urogenital reconstructive surgery Lotte Kaasgaard Jakobsen1 Professor Henning Olsen1 Overlæge Gitte Hvistendahl1 Professor Karl-Erik Andersson2 1 – Dept. of Urology, Aarhus University Hospital 2 – Dept. of Gynecology and Obstetrics, Aarhus University hospital Background: Congenital obstruction...

  4. Reconstructing Progressive Education

    Science.gov (United States)

    Kaplan, Andy

    2013-01-01

    The work of Colonel Francis W. Parker, the man whom Dewey called "the father of progressive education," provides a starting point for reconstructing the loose ambiguities of progressive education into a coherent social and educational philosophy. Although progressives have claimed their approach is more humane and sensitive to children, we need…

  5. Perturbative High Harmonic Wave Front Control.

    Science.gov (United States)

    Li, Zhengyan; Brown, Graham; Ko, Dong Hyuk; Kong, Fanqi; Arissian, Ladan; Corkum, P B

    2017-01-20

    We pattern the wave front of a high harmonic beam by intersecting the intense driving laser pulse that generates the high harmonic with a weak control pulse. To illustrate the potential of wave-front control, we imprint a Fresnel zone plate pattern on a harmonic beam, causing the harmonics to focus and defocus. The quality of the focus that we achieve is measured using the spectral wave-front optical reconstruction by diffraction method. We will show that it is possible to enhance the peak intensity by orders of magnitude without a physical optical element in the path of the extreme ultraviolet (XUV) beam. Through perturbative wave-front control, XUV beams can be created with a flexibility approaching what technology allows for visible and infrared light.

  6. Implementation of Cognitive-Behavioral Substance Abuse Treatment in Sub-Saharan Africa: Treatment Engagement and Abstinence at Treatment Exit.

    Science.gov (United States)

    Gouse, Hetta; Magidson, Jessica F; Burnhams, Warren; Remmert, Jocelyn E; Myers, Bronwyn; Joska, John A; Carrico, Adam W

    2016-01-01

    This study documented the treatment cascade for engagement in care and abstinence at treatment exit as well as examined correlates of these outcomes for the first certified Matrix Model® substance abuse treatment site in Sub-Saharan Africa. This retrospective chart review conducted at a resource-limited community clinic in Cape Town, South Africa, assessed treatment readiness and substance use severity at treatment entry as correlates of the number of sessions attended and biologically confirmed abstinence at treatment exit among 986 clients who initiated treatment from 2009-2014. Sociodemographic and clinical correlates of treatment outcomes were examined using logistic regression, modeling treatment completion and abstinence at treatment exit separately. Of the 2,233 clients who completed screening, approximately 44% (n = 986) initiated treatment. Among those who initiated treatment, 45% completed at least four group sessions, 30% completed early recovery skills training (i.e., at least eight group sessions), and 13% completed the full 16-week program. Approximately half (54%) of clients who provided a urine sample had negative urine toxicology results for any substance at treatment exit. Higher motivation at treatment entry was independently associated with greater odds of treatment completion and negative urine toxicology results at treatment exit. Findings provide initial support for the successful implementation the Matrix Model in a resource-limited setting. Motivational enhancement interventions could support treatment initiation, promote sustained engagement in treatment, and achieve better treatment outcomes.

  7. Fibroblast Growth Factor 21 Promotes C2C12 Cells Myogenic Differentiation by Enhancing Cell Cycle Exit

    Directory of Open Access Journals (Sweden)

    Xinyi Liu

    2017-01-01

    Full Text Available Fibroblast growth factor 21 (FGF21, a secretion protein, functions as a pivotal regulator of energy metabolism and is being considered as a therapeutic candidate in metabolic syndromes. However, the roles of FGF21 in myogenic differentiation and cell cycle remain obscure. In this study, we investigated the function of FGF21 in myogenesis and cell cycle exit using C2C12 cell line. Our data showed that the expression of myogenic genes as well as cell cycle exit genes was increased after FGF21 overexpression, and FGF21 overexpression induces cell cycle arrest. Moreover, cell cycle genes were decreased in FGF21 overexpression cells while they were increased in FGF21 knockdown cells. Further, FGF21/P53/p21/Cyclin-CDK has been suggested as the key pathway for cell cycle exit mediated by FGF21 in C2C12 cells. Also, we deduce that FGF21 promotes the initiation of myogenic differentiation mainly through enhancing cell cycle exit of C2C12 cells. Taken together, our results demonstrated that FGF21 promotes cell cycle exit and enhances myogenic differentiation of C2C12 cells. This study provided new evidence that FGF21 promotes myogenic differentiation, which could be useful for better understanding the roles of FGF21 in myogenesis.

  8. Breast reconstruction: Correlation between different procedures, reconstruction timing and complications

    Directory of Open Access Journals (Sweden)

    Anđelkov Katarina

    2011-01-01

    Full Text Available Introduction. Improved psychophysical condition after breast reconstruction in women has been well documented Objective. To determine the most optimal technique with minimal morbidity, the authors examined their results and complications based on reconstruction timing (immediate and delayed reconstruction and three reconstruction methods: TRAM flap, latissimus dorsi flap and reconstruction with tissue expanders and implants. Methods. Reconstruction was performed in 60 women of mean age 51.1 years. We analyzed risk factors: age, body mass index (BMI, smoking history and radiation therapy in correlation with timing and method of reconstruction. Complications of all three methods of reconstruction were under 1.5-2-year follow-up after the reconstruction. All data were statistically analyzed. Results. Only radiation had significant influence on the occurrence of complications both before and after the reconstruction, while age, smoking and BMI had no considerable influence of the development of complications. There were no statistically significant correlation between the incidence of complications, time and method of reconstruction. Conclusion. Any of the aforementioned breast reconstruction techniques can yield good results and a low rate of re-operations. To choose the best method, the patient needs to be as well informed as possible about the options including the risks and benefits of each method.

  9. A High Precision Terahertz Wave Image Reconstruction Algorithm

    National Research Council Canada - National Science Library

    Guo, Qijia; Chang, Tianying; Geng, Guoshuai; Jia, Chengyan; Cui, Hong-Liang

    2016-01-01

    With the development of terahertz (THz) technology, the applications of this spectrum have become increasingly wide-ranging, in areas such as non-destructive testing, security applications and medical scanning, in which one of the most...

  10. Speech coding, reconstruction and recognition using acoustics and electromagnetic waves

    Science.gov (United States)

    Holzrichter, John F.; Ng, Lawrence C.

    1998-01-01

    The use of EM radiation in conjunction with simultaneously recorded acoustic speech information enables a complete mathematical coding of acoustic speech. The methods include the forming of a feature vector for each pitch period of voiced speech and the forming of feature vectors for each time frame of unvoiced, as well as for combined voiced and unvoiced speech. The methods include how to deconvolve the speech excitation function from the acoustic speech output to describe the transfer function each time frame. The formation of feature vectors defining all acoustic speech units over well defined time frames can be used for purposes of speech coding, speech compression, speaker identification, language-of-speech identification, speech recognition, speech synthesis, speech translation, speech telephony, and speech teaching.

  11. MO-E-BRB-04: Real-Time Exit-Fluence Delivery Validation

    Energy Technology Data Exchange (ETDEWEB)

    Siebers, J. [University of Virginia Health System (United States)

    2015-06-15

    Recent high profile reports of technical failures and human errors causing severe radiation- induced injuries and deaths come in support of the sustained efforts to ensure patient safety in the delivery of radiation treatments. In addition, highly conformal radiation therapies and escalated fraction doses mandate increased and sustained accuracy of the entire radiotherapy process. Consequently, and as a Result of AAPM and ASTRO led efforts patient specific quality assurance for specialized radiation treatments such as IMRT, SRS/SBRT and Arc Therapy had become a three-tier process: Pre-treatment, during treatment, and post treatment patient specific QA. Traditional patient QA consists of pre-treatment data transfer integrity dosimetric verifications and during-treatment geometric verifications. However, as treatment adaptation becomes closer to deployment in the clinics, during treatment validation via exit detectors had become a realistic QA option, permitting plan assessment in near real time. Post-treatment, machine logs allow comparisons of a range of mechanical parameters. A combination of these techniques could be used in evaluating inter-fraction, and intra-fraction delivery over a long time period such as an year, to evaluate the significant errors per site, per treatment technique. This type of data mining over longer periods of time provides the potential to recognize suboptimal radiation treatments, while allowing to identify systematic, possibly significant errors. This would allow creation of a data base of realized errors, small and large in dosimetry that could be for process or equipment improvement. This educational symposium will describe and review patient QA techniques, results, and strategies for patient specific quality assurance. Learning Objectives: review the goals of pre-treatment QA for various specialized procedures review methods and means for pre-treatment QA, limitations and tolerances review the scenarios where Varian/Tomo Log files

  12. Evolution of wave and tide over vegetation region in nearshore waters

    Science.gov (United States)

    Zhang, Mingliang; Zhang, Hongxing; Zhao, Kaibin; Tang, Jun; Qin, Huifa

    2017-08-01

    Coastal wetlands are an important ecosystem in nearshore regions, where complex flow characteristics occur because of the interactions among tides, waves, and plants, especially in the discontinuous flow of the intertidal zone. In order to simulate the wave and wave-induced current in coastal waters, in this study, an explicit depth-averaged hydrodynamic (HD) model has been dynamically coupled with a wave spectral model (CMS-Wave) by sharing the tide and wave data. The hydrodynamic model is based on the finite volume method; the intercell flux is computed using the Harten-Lax-van Leer (HLL) approximate Riemann solver for computing the dry-to-wet interface; the drag force of vegetation is modeled as the sink terms in the momentum equations. An empirical wave energy dissipation term with plant effect has been derived from the wave action balance equation to account for the resistance induced by aquatic vegetation in the CMS-Wave model. The results of the coupling model have been verified using the measured data for the case with wave-tide-vegetation interactions. The results show that the wave height decreases significantly along the wave propagation direction in the presence of vegetation. In the rip channel system, the oblique waves drive a meandering longshore current; it moves from left to right past the cusps with oscillations. In the vegetated region, the wave height is greatly attenuated due to the presence of vegetation, and the radiation stresses are noticeably changed as compared to the region without vegetation. Further, vegetation can affect the spatial distribution of mean velocity in a rip channel system. In the co-exiting environment of tides, waves, and vegetation, the locations of wave breaking and wave-induced radiation stress also vary with the water level of flooding or ebb tide in wetland water, which can also affect the development and evolution of wave-induced current.

  13. Retrospectively assessed physical work environment during working life and risk of sickness absence and labour market exit among older workers

    DEFF Research Database (Denmark)

    Sundstrup, Emil; Hansen, Åse Marie; Mortensen, Erik Lykke

    2017-01-01

    OBJECTIVE: To determine the prospective association between retrospectively assessed physical work environment during working life and prospectively assessed sickness absence and labour market exit among older workers. METHODS: Using Cox regression analyses we estimated the 4-year to 6-year...... and exposure to several factors in the physical work environment, especially heavy lifting, were important for labour market exit and sickness absence. This study underscores the importance of reducing physical work exposures throughout the working life course for preventing sickness absence and premature exit...... prospective risk of register-based long-term sickness absence (LTSA), disability pension, early retirement and unemployment from exposure to different physical work environmental factors during working life among 5076 older workers (age 49-63 at baseline) from the Copenhagen Aging and Midlife Biobank cohort...

  14. Effect of Nascent Peptide Steric Bulk on Elongation Kinetics in the Ribosome Exit Tunnel.

    Science.gov (United States)

    Po, Pengse; Delaney, Erin; Gamper, Howard; Szantai-Kis, D Miklos; Speight, Lee; Tu, LiWei; Kosolapov, Andrey; Petersson, E James; Hou, Ya-Ming; Deutsch, Carol

    2017-06-16

    All proteins are synthesized by the ribosome, a macromolecular complex that accomplishes the life-sustaining tasks of faithfully decoding mRNA and catalyzing peptide bond formation at the peptidyl transferase center (PTC). The ribosome has evolved an exit tunnel to host the elongating new peptide, protect it from proteolytic digestion, and guide its emergence. It is here that the nascent chain begins to fold. This folding process depends on the rate of translation at the PTC. We report here that besides PTC events, translation kinetics depend on steric constraints on nascent peptide side chains and that confined movements of cramped side chains within and through the tunnel fine-tune elongation rates. Copyright © 2017 Elsevier Ltd. All rights reserved.

  15. Do host country education and language training help recent immigrants exit poverty?

    Science.gov (United States)

    Kaida, Lisa

    2013-05-01

    Despite growing interest in host country-specific skills, quantitative assessments of the economic benefit of host country education and training for immigrants are limited. This study addresses this gap by evaluating the impacts of host country formal education and language training on the exit from family poverty among recently arrived immigrant adults. The bivariate probit model and propensity weighting approach are used to analyze data from the Longitudinal Survey of Immigrants to Canada. Results suggest that while English/French language training is beneficial for low income recent immigrants in general, host country education benefits only highly educated recent arrivals. This study underscores the importance of considering immigrants' selectivity into host country education and training, as simple regression analysis can improperly estimate their true benefits. Copyright © 2013 Elsevier Inc. All rights reserved.

  16. Build to order and entry/exit strategies under exchange rate uncertainty

    Directory of Open Access Journals (Sweden)

    Lin Chin-Tsai

    2004-01-01

    Full Text Available Under uncertainty of exchange rate, we extend the build to order production model of Lin et al. (2002 by considering the export-oriented manufacturer to make decisions to switch production location freely between domestic and foreign ones. The export-oriented manufacturer is risk neutral and has rational expectations. When we transfer the production location from domestic (foreign to foreign (domestic, and the production location transferring cost and the drift of real exchange rate are both equal to zero, then the optimal entry and exit threshold value of Cobb-Douglas production function are equal, no matter whether we use real options or net present value method. Thus export-oriented manufacturer can make decisions at the optimal transfer threshold value for transferable locations wherever the production locations are. It provides the export-oriented manufacturer with another way of thinking.

  17. INVESTIGATION OF VISITOR MOTIVATION OF THE EXIT MUSIC FESTIVAL (THE REPUBLIC OF SERBIA

    Directory of Open Access Journals (Sweden)

    Ivana BLEŠIĆ

    2014-12-01

    Full Text Available The decision to visit a festival or an event is a directed activity initiated by a wish to fulfil certain cultural need. Although motives only represent one of the variables describing visitor behaviour (besides learning, cultural conditioning and social influences, they form a crucial point that initiates decision making. The purpose of this study was to develop a measurement instrument that can be used to measure the most significant festival motivators for visitors’ travels to music festivals. The paper delivers the results of a questionnaire research conducted during the 11th EXIT festival (Petrovaradin Fortress, Novi Sad, The Republic of Serbia in July 2011. The results were based on 566 questionnaires. The factor analysis generated three items: socialization; exploration of the festival programme and atmosphere; and perception of the festival and learning.

  18. CFD Analysis of Nozzle Exit Position Effect in Ejector Gas Removal System in Geothermal Power Plant

    Directory of Open Access Journals (Sweden)

    Setyo Nugroho

    2015-06-01

    Full Text Available The single stage ejector is used to extract the Non CondensableGas (NCG in the condenser using the working principle of the Venturi tube. Three dimensional computational simulation of the ejector according to the operating conditions was conducted to determine the flow in the ejector. Motive steam entering through the convergent – divergent nozzle with increasing flow velocity so that the low pressure exist around the nozzle. Comparison is done also in a two dimensional simulation to know the differences occurring phenomena and flow inside ejector. Different simulation results obtained between two dimensional and three dimensional simulation. Reverse flow which occurs in the mixing chamber made the static pressure in the area has increased dramatically. Then the variation performed on Exit Nozzle Position (NXP to determine the changes of the flow of the NCG and the vacuum level of the ejector. Keywords: Ejector, NCG, CFD, Compressible flow.

  19. SRB/SLEEC (Solid Rocket Booster/Shingle Lap Extendible Exit Cone) feasibility study, volume 1

    Science.gov (United States)

    Baker, William H., Jr.

    1986-01-01

    A preliminary design and analysis was completed for a SLEEC (Shingle Lap Extendible Exit Cone) which could be incorporated on the Space Transportation System (STS) Solid Rocket Booster (SRB). Studies were completed which predicted weights and performance increases and development plans were prepared for the full-scale bench and static test of SLEEC. In conjunction with the design studies, a series of supporting analyses were performed to assure the validity and feasibility of performance, fabrication, cost, and reliability for the selected design. The feasibility and required amounts of bench, static firing, and flight tests considered necessary for the successful incorporation of SLEEC on the Shuttle SRBs were determined. Preliminary plans were completed which define both a follow on study effort and a development program.

  20. Characterization of Carbon Particulates in the Exit Flow of a Plasma Pyrolysis Assembly (PPA) Reactor

    Science.gov (United States)

    Green, Robert D.; Meyer, Marit E.; Agui, Juan H.; Berger, Gordon M.; Vijayakumar, R.; Abney, Morgan B.; Greenwood, Zachary

    2015-01-01

    The ISS presently recovers oxygen from crew respiration via a Carbon Dioxide Reduction Assembly (CRA) that utilizes the Sabatier chemical process to reduce captured carbon dioxide to methane (CH4) and water. In order to recover more of the hydrogen from the methane and increase oxygen recovery, NASA Marshall Space Flight Center (MSFC) is investigating a technology, plasma pyrolysis, to convert the methane to acetylene. The Plasma Pyrolysis Assembly (or PPA), achieves 90% or greater conversion efficiency, but a small amount of solid carbon particulates are generated as a side product and must be filtered before the acetylene is removed and the hydrogen-rich gas stream is recycled back to the CRA. In this work, we present the experimental results of an initial characterization of the carbon particulates in the PPA exit gas stream. We also present several potential options to remove these carbon particulates via carbon traps and filters to minimize resupply mass and required downtime for regeneration.

  1. Ascaris exit through the feeding jejunostomy tract: a rare case report.

    Science.gov (United States)

    Wani, Mohd Lateef; Rather, Ajaz Ahmad; Irshad, Ifat; Hakeem, Zubair Ashraf; Bijli, Akram Hussain; Khan, Tahir Saleem; Lone, Reyaz Ahmad

    2011-01-01

    A 65-year-old male was operated for esophageal carcinoma. Transhiatal esophagogastrectomy with jejunostomy feeding tube was done. Orals were started on the 12th postoperative day. The jejunostomy feeding tube was removed on the 20th postoperative day. Immediately after removal of the feeding tube, a 10-12 cm ascaris was seen emerging through the jejunostomy tract. Ascaris lumbricoides can cause a variety of complications like intestinal obstruction, perforation, biliary obstruction, pancreatitis, liver abscess, cholangiohepatitis, volvulus, and gangrene, etc. Although the above-mentioned complications have been frequently reported, ascaris exit through the feeding jejunostomy tract is very rare. This case is reported here to emphasize the importance of this complication of wandering ascariasis.

  2. Increased Jet Noise Due to a "Nominally Laminar" State of Nozzle Exit Boundary Layer

    Science.gov (United States)

    Zaman, K. B. M. Q.

    2017-01-01

    A set of 2-inch diameter nozzles is used to investigate the effect of varying exit boundary layer state on the radiated noise from high-subsonic jets. It is confirmed that nozzles involving turbulent boundary layers are the quietest while nozzles involving a nominally-laminar boundary layer are loud especially on the high-frequency side of the sound pressure level spectrum. The latter boundary layer state involves a Blasius-like mean velocity profile but higher turbulence intensities compared to those in the turbulent state. The higher turbulence in the initial region of the jet shear layer leads to increased high-frequency noise. The results strongly suggest that an anomaly noted with subsonic jet noise databases in the literature is due to a similar effect of differences in the initial boundary layer state.

  3. A redox switch shapes the Lon protease exit pore to facultatively regulate proteolysis.

    Science.gov (United States)

    Nishii, Wataru; Kukimoto-Niino, Mutsuko; Terada, Takaho; Shirouzu, Mikako; Muramatsu, Tomonari; Kojima, Masaki; Kihara, Hiroshi; Yokoyama, Shigeyuki

    2015-01-01

    The Lon AAA+ protease degrades damaged or misfolded proteins in its intramolecular chamber. Its activity must be precisely controlled, but the mechanism by which Lon is regulated in response to different environments is not known. Facultative anaerobes in the Enterobacteriaceae family, mostly symbionts and pathogens, encounter both anaerobic and aerobic environments inside and outside the host's body, respectively. The bacteria characteristically have two cysteine residues on the Lon protease (P) domain surface that unusually form a disulfide bond. Here we show that the cysteine residues act as a redox switch of Lon. Upon disulfide bond reduction, the exit pore of the P-domain ring narrows by ∼30%, thus interrupting product passage and decreasing activity by 80%; disulfide bonding by oxidation restores the pore size and activity. The redox switch (E°' = -227 mV) is appropriately tuned to respond to variation between anaerobic and aerobic conditions, thus optimizing the cellular proteolysis level for each environment.

  4. How to Enter, Fly In, and Exit the A-Train Constellation

    Science.gov (United States)

    Vincent, Mark A.

    2015-01-01

    The collaborative science obtained from the satellites in the A-Train is an unparalleled success. The constellation framework that has evolved is well-formulated and documented by its international members. Communication between teams is enhanced by a web-based Constellation Coordination System. Safety and correlated observations are ensured by defining independent control boxes with buffers in between. Each mission stays within its control box by regular drag makeup maneuvers. Annual inclination adjustments are coordinated by all missions to maintain their absolute and relative Mean Local Time of Ascending Node (MLTAN). Since the satellites are in different orbit planes their separation involves a three-dimensional triad made up of the along track separations, reference groundtracks and MLTAN's. For further safety, a Constellation Envelope has been defined to determine safe entry and exit orbits.

  5. [Nurses' working conditions, health and well being in Europe (Nurses' Early Exit Study)].

    Science.gov (United States)

    Camerino, Donatella; Mansano Sarquis, Leila Maria

    2010-01-01

    Nurses' shortage and a high turnover cause concern in Europe. The Nurses' Early Exit Study (NEXT) is a cross-cultural and longitudinal project funded by the European Union to ascertain the reasons of these trends. Ten European countries and 56.406 nurses were involved. The goal was to analyze the relationship between working conditions and nursing workers' health. Data from 19.099 nurses were analyzed by means of descriptive and linear regression analyses. The nurses' perception of working conditions, classified by cluster analysis, resulted a good predictor of workers' health and well being and adequately reflected their real working and life conditions. The differences among countries are likely justified by cultural, socioeconomic and organizational variety. Interventions to reduce nurses' turnover must consider obstacles and facilitations in the professional development. Nurses' engagement in processes that impact on political, organizational and ergonomic choices is worthwhile.

  6. 'Contexts of Exit in the Migration of Russian Speakers from the Baltic Countries to Ireland'

    Science.gov (United States)

    Aptekar, Sofya

    2009-12-01

    Recently, Ireland has become a major destination for migrants from Estonia, Latvia, and Lithuania. Many of these migrants are members of Russian-speaking minorities leaving a context of restrictive citizenship and language laws and varying degrees of ethnic tension. This paper draws on interviews collected in Ireland to examine the role played by the contexts of exit in decisions to migrate among Russian-speaking minorities from the Baltics. The results suggest that Russian speakers from Estonia migrate because of their experiences as minorities, while those from Latvia and Lithuania migrate to escape low wages and irregular employment. This is so despite equally restrictive language and citizenship laws in Estonia and Latvia. I argue that the effect of state policy as a push factor for minority emigration is mediated by other contextual aspects, such as levels of contact, timbre of ethnic relations, and the degree of intersection between economic stratification and ethnicity.

  7. The Effect of Sanctions and Active Labour Market Programmes on the Exit Rate From Unemployment

    DEFF Research Database (Denmark)

    Ahmad, Nisar; Svarer, Michael

    2009-01-01

    ). Hence, modeling only one of them as treatment might over or underestimate the true effect. Therefore, by using a multivariate mixed proportional hazard model (MMPH), we model the hazard rate out of unemployment along with the sanction rate and hazard rate into active labour market programmes. We......This paper simultaneously investigates the effectiveness of benefit sanctions and active labour market programmes on the exit rate from unemployment using Danish data. In the data about one third of the individuals who are sanctioned also participate in some active labour market programmes (ALMPs...... optimally select the number of supports point for the distribution of unobserved heterogeneity. Results show that pre-specifying two support points underestimates the effect of sanctions and active labour market programmes. Failing to control for selectivity for sanctions not only underestimates...

  8. Educational Inequalities in Exit from Paid Employment among Dutch Workers: The Influence of Health, Lifestyle and Work.

    Directory of Open Access Journals (Sweden)

    Suzan J W Robroek

    Full Text Available Individuals with lower socioeconomic status are at increased risk of involuntary exit from paid employment. To give sound advice for primary prevention in the workforce, insight is needed into the role of mediating factors between socioeconomic status and labour force participation. Therefore, it is aimed to investigate the influence of health status, lifestyle-related factors and work characteristics on educational differences in exit from paid employment.14,708 Dutch employees participated in a ten-year follow-up study during 1999-2008. At baseline, education, self-perceived health, lifestyle (smoking, alcohol, sports, BMI and psychosocial (demands, control, rewards and physical work characteristics were measured by questionnaire. Employment status was ascertained monthly based on tax records. The relation between education, health, lifestyle, work-characteristics and exit from paid employment through disability benefits, unemployment, early retirement and economic inactivity was investigated by competing risks regression analyses. The mediating effects of these factors on educational differences in exit from paid employment were tested using a stepwise approach.Lower educated workers were more likely to exit paid employment through disability benefits (SHR:1.84, unemployment (SHR:1.74, and economic inactivity (SHR:1.53 but not due to early retirement (SHR:0.92. Poor or moderate health, an unhealthy lifestyle, and unfavourable work characteristics were associated with disability benefits and unemployment, and an unhealthy lifestyle with economic inactivity. Educational differences in disability benefits were explained for 40% by health, 31% by lifestyle, and 12% by work characteristics. For economic inactivity and unemployment, up to 14% and 21% of the educational differences could be explained, particularly by lifestyle-related factors.There are educational differences in exit from paid employment, which are partly mediated by health

  9. Educational Inequalities in Exit from Paid Employment among Dutch Workers: The Influence of Health, Lifestyle and Work.

    Science.gov (United States)

    Robroek, Suzan J W; Rongen, Anne; Arts, Coos H; Otten, Ferdy W H; Burdorf, Alex; Schuring, Merel

    2015-01-01

    Individuals with lower socioeconomic status are at increased risk of involuntary exit from paid employment. To give sound advice for primary prevention in the workforce, insight is needed into the role of mediating factors between socioeconomic status and labour force participation. Therefore, it is aimed to investigate the influence of health status, lifestyle-related factors and work characteristics on educational differences in exit from paid employment. 14,708 Dutch employees participated in a ten-year follow-up study during 1999-2008. At baseline, education, self-perceived health, lifestyle (smoking, alcohol, sports, BMI) and psychosocial (demands, control, rewards) and physical work characteristics were measured by questionnaire. Employment status was ascertained monthly based on tax records. The relation between education, health, lifestyle, work-characteristics and exit from paid employment through disability benefits, unemployment, early retirement and economic inactivity was investigated by competing risks regression analyses. The mediating effects of these factors on educational differences in exit from paid employment were tested using a stepwise approach. Lower educated workers were more likely to exit paid employment through disability benefits (SHR:1.84), unemployment (SHR:1.74), and economic inactivity (SHR:1.53) but not due to early retirement (SHR:0.92). Poor or moderate health, an unhealthy lifestyle, and unfavourable work characteristics were associated with disability benefits and unemployment, and an unhealthy lifestyle with economic inactivity. Educational differences in disability benefits were explained for 40% by health, 31% by lifestyle, and 12% by work characteristics. For economic inactivity and unemployment, up to 14% and 21% of the educational differences could be explained, particularly by lifestyle-related factors. There are educational differences in exit from paid employment, which are partly mediated by health, lifestyle and work

  10. Construction of an easy-to-use CRISPR-Cas9 system by patching a newly designed EXIT circuit.

    Science.gov (United States)

    Tang, Qiang; Lou, Chunbo; Liu, Shuang-Jiang

    2017-01-01

    Plasmid-borne genetic editing tools, including the widely used CRISPR-Cas9 system, have greatly facilitated bacterial programming to obtain novel functionalities. However, the lack of effective post-editing plasmid elimination methods impedes follow-up genetic manipulation or application. Conventional strategies including exposure to physical and chemical treatments, or exploiting temperature-sensitive replication origins have several drawbacks (e.g., they are limited for efficiency and are time-consuming). Therefore, the demand is apparent for easy and rapid elimination of the tool plasmids from their bacterial hosts after genetic manipulation. To bridge this gap, we designed a novel EXIT circuit with the homing endonuclease, which can be exploited for rapid and efficient elimination of various plasmids with diverse replication origins. As a proof of concept, we validated the EXIT circuit in Escherichia coli by harnessing homing endonuclease I-SceI and its cleavage site. When integrated into multiple plasmids with different origins, the EXIT circuit allowed them to be eliminated from the host cells, simultaneously. By combining the widely used plasmid-borne CRISPR-Cas9 system and the EXIT circuit, we constructed an easy-to-use CRISPR-Cas9 system that eliminated the Cas9- and the single-guide RNA (sgRNA)-encoding plasmids in one-step. Within 3 days, we successfully constructed an atrazine-degrading E. coli strain, thus further demonstrating the advantage of this new CRISPR-Cas9 system for bacterial genome editing. Our novel EXIT circuit, which exploits the homing endonuclease I-SceI, enables plasmid(s) with different replication origins to be eliminated from their host cells rapidly and efficiently. We also developed an easy-to-use CRISPR-Cas9 system with the EXIT circuit, and this new system can be widely applied to bacterial genome editing.

  11. Procedimento intraparto extra-uterino (EXIT num caso de linfangiona cervical

    Directory of Open Access Journals (Sweden)

    Fátima Ribeiro

    2016-02-01

    Full Text Available Introdução: Fetos com diagnóstico pré-natal de malformações anatómicas envolvendo a face e/ou o pescoço estão em risco de obstrução das vias aéreas desde o pós-natal imediato. A programação de medidas periparto que previnam a compressão das vias aéreas, mantendo uma adequada circulação fetal, é fundamental no prognóstico. Caso Clínico: Feto com diagnóstico ecográfico, às 31 semanas de gestação, de volumosa massa cervical e facial, compatível com linfangioma quístico. O caso foi discutido em equipa multidisciplinar, tendo sido decidida a realização de cesariana associada ao procedimento EXIT às 39 semanas de gestação. Após exteriorização do polo cefálico, foi confirmada massa cervical e facial direita, sendo o feto sujeito a intubação oro-traqueal no primeiro minuto. Ao sexto dia de vida foi submetido a cirurgia, com excisão parcial da massa. Conclusão: O procedimento EXIT permite a manutenção de uma adequada oxigenação fetal enquanto se estabelece uma via aérea patente. Uma adequada coordenação da equipa multi-disciplinar é fundamental para o êxito da técnica.

  12. Facial affect recognition and exit examination performance in medical students: a prospective exploratory study.

    Science.gov (United States)

    Roos, Tessa C; Niehaus, Dana J H; Leppänen, Jukka M; Ras, Johan; Cloete, Karen J; Jordaan, Esmè; Koen, Liezl

    2014-11-28

    Facial affect recognition (FAR) abilities underpin emotional intelligence (EI). The latter is suggested to predict academic success and to be important for clinician-patient interaction. It is therefore of interest to investigate the possible association between FAR and academic performance in undergraduate medical students. We assessed the association between the ability to recognize emotions through facial expression and exit examination performance, a measure of clinical proficiency, in undergraduate medical students stratified by gender at a South African tertiary institution using a prospective descriptive design. Data on the perception of facial expressions and exit examination marks were obtained from 144 (61%) females and 93 (39%) males with a mean age of 24.1 ± 1.6 years. Facial affect recognition measures on the Hexagon and Animation tasks were individually correlated with academic performance indicators using Pearson correlation. The perceptual discrimination of anger was associated with improved performance in anaesthetics (r = .24; p = .004) and urology (r = .24; p = .001), while the recognition of happiness was associated with decreased performance in obstetrics (r = -.21, p = .002). Gender was an effect modifier in the relationship between perceptual discrimination of anger and urology performance (p = .03), with a strong positive relationship for males, but a non-significant relationship for females. There was no overall correlation between FAR and overall academic performance or with gender. However, subject (specialty) specific findings with recognition of specific emotions and with gender as effect modifier poses interesting questions about EI and FAR and prompts further research into FAR as a useful tool. Being an objective test and offering a more focused assessment makes FAR worthy of further application.

  13. Zeb2 Regulates Cell Fate at the Exit from Epiblast State in Mouse Embryonic Stem Cells.

    Science.gov (United States)

    Stryjewska, Agata; Dries, Ruben; Pieters, Tim; Verstappen, Griet; Conidi, Andrea; Coddens, Kathleen; Francis, Annick; Umans, Lieve; van IJcken, Wilfred F J; Berx, Geert; van Grunsven, Leo A; Grosveld, Frank G; Goossens, Steven; Haigh, Jody J; Huylebroeck, Danny

    2017-03-01

    In human embryonic stem cells (ESCs) the transcription factor Zeb2 regulates neuroectoderm versus mesendoderm formation, but it is unclear how Zeb2 affects the global transcriptional regulatory network in these cell-fate decisions. We generated Zeb2 knockout (KO) mouse ESCs, subjected them as embryoid bodies (EBs) to neural and general differentiation and carried out temporal RNA-sequencing (RNA-seq) and reduced representation bisulfite sequencing (RRBS) analysis in neural differentiation. This shows that Zeb2 acts preferentially as a transcriptional repressor associated with developmental progression and that Zeb2 KO ESCs can exit from their naïve state. However, most cells in these EBs stall in an early epiblast-like state and are impaired in both neural and mesendodermal differentiation. Genes involved in pluripotency, epithelial-to-mesenchymal transition (EMT), and DNA-(de)methylation, including Tet1, are deregulated in the absence of Zeb2. The observed elevated Tet1 levels in the mutant cells and the knowledge of previously mapped Tet1-binding sites correlate with loss-of-methylation in neural-stimulating conditions, however, after the cells initially acquired the correct DNA-methyl marks. Interestingly, cells from such Zeb2 KO EBs maintain the ability to re-adapt to 2i + LIF conditions even after prolonged differentiation, while knockdown of Tet1 partially rescues their impaired differentiation. Hence, in addition to its role in EMT, Zeb2 is critical in ESCs for exit from the epiblast state, and links the pluripotency network and DNA-methylation with irreversible commitment to differentiation. Stem Cells 2017;35:611-625. © 2016 The Authors Stem Cells published by Wiley Periodicals, Inc. on behalf of AlphaMed Press.

  14. Thermoregulation in juvenile red kangaroos (Macropus rufus) after pouch exit: higher metabolism and evaporative water requirements.

    Science.gov (United States)

    Munn, A J; Dawson, T J

    2001-01-01

    The population dynamics of red kangaroos (Macropus rufus) in the Australian arid zone is tightly linked with environmental factors, which partly operate via the survival of juvenile animals. A crucial stage is the young-at-foot (YAF) stage when kangaroos permanently exit the pouch. We have examined the thermal biology of YAF red kangaroos during ages from permanent pouch exit until weaning. Over a wide range of environmental temperatures (ambient temperature [T(a)] -5 degrees to 45 degrees C), YAF red kangaroos had a mass-specific metabolism that was generally twice that of adults, considerably higher than would be expected for an adult marsupial of their body size. The total energy requirements of YAF red kangaroos were 60%-70% of those of adult females, which were three times their size. Over the same range in T(a), YAF red kangaroos also had total evaporative water losses equal to those of adult females. At the highest T(a) (45 degrees C), differences were noted in patterns of dry heat loss (dry conductance) between YAF red kangaroos and adult females, which may partially explain the relatively high levels of evaporative cooling by YAF. By weaning age, young kangaroos showed little change in their basal energy and water requirements (at T(a) 25 degrees C) but did show reduced mass-specific costs in terms of energy and water use at extremes of T(a) (-5 degrees and 45 degrees C, respectively). In their arid environment, typified by unpredictable rainfall and extremes of T(a), young red kangaroos may need to remain close to water points, which, in turn, may restrict their ability to find the high-quality forage needed to meet their high energy demands.

  15. Experimental study of novel passive control methods to improve combustor exit temperature uniformity

    Science.gov (United States)

    Gupta, Alka; Ibrahim, Mohamed Saeed; Amano, R. S.

    2015-01-01

    The effect of non-uniform temperature flow which comes in contact with the turbine blades is of paramount importance since the thermal damage that occur to the blade during its operation, is governed by the non-uniformities present in the oncoming flow. This thermal damage leads to increased maintenance cost and reduced life-span of the turbine blades. This paper investigates the effectiveness of some novel passive control techniques to improve the temperature uniformity of the combustor exit flow to address the need to reduce the thermal damage and hence decrease the overall maintenance cost of the gas turbine system. The novel passive control techniques tested in this study include the use of streamlined body or guide vanes in the dilution zone of the combustor. For the guide vanes four different orientations were tested—0°, 30°, 60°, 90°. Extensive experimentation was conducted under different flow conditions. The deviation of the exit temperature from the equilibrium mixing temperature was used to compare the effectiveness of different passive control techniques. It was found that the 30o guide vanes gave the most uniform temperature flow under majority of cases considered. On an average, the flow with 30o guide vanes was about 15 % more uniform in temperature as compared to the staggered holes geometry with only 1 % higher pressure loss. The possible reason for this improvement is the combination of swirl and depth to which the dilution flow can enter the dilution zone and mix with the primary hot flow. The streamlined body came second with an improvement in pressure losses. Based on these experimental findings, the use of these guide vanes and streamlined body has potential in the gas turbine industry to deal with the high maintenance cost involved in these systems.

  16. Efficient Wave Energy Amplification with Wave Reflectors

    DEFF Research Database (Denmark)

    Kramer, Morten Mejlhede; Frigaard, Peter Bak

    2002-01-01

    Wave Energy Converters (WEC's) extract wave energy from a limited area, often a single point or line even though the wave energy is generally spread out along the wave crest. By the use of wave reflectors (reflecting walls) the wave energy is effectively focused and increased to approximately 130......-140%. In the paper a procedure for calculating the efficiency and optimizing the geometry of wave reflectors are described, this by use of a 3D boundary element method. The calculations are verified by laboratory experiments and a very good agreement is found. The paper gives estimates of possible power benifit...... for different geometries of the wave reflectors and optimal geometrical design parameters are specified. On this basis inventors of WEC's can evaluate whether a specific WEC possible could benefit from wave reflectors....

  17. Bacterial colonization patterns in daily chlorhexidine care at the exit site in peritoneal dialysis patients—A prospective, randomized controlled trial

    OpenAIRE

    Wang, Hsi-Hao; Hung, Shih-Yuan; Chang, Min-Yu; Lee, Yi-Che; Lin, Hsiu-Fang; Lin, Tsun-Mei; Yang, Su-Pen; Lin, Hsi-Hsun; Yang, Su-Ching; Wang, Jiun-Ling

    2017-01-01

    Bacterial colonization patterns in daily chlorhexidine care at the exit site in peritoneal dialysis (PD) patients were not known. We performed a prospective, randomized controlled trial enrolling 89 PD patients. After stratification by initial Staphylococcus aureus (SA) carrier status, patients were randomly assigned to receive daily 4% chlorhexidine care (intervention group) or normal saline (control group) at the exit site. Monthly, we cultured bacteria from the exit site and nasal swabs fo...

  18. Analysis of the trip costs of a traffic corridor with two entrances and one exit under car-following model

    Science.gov (United States)

    Tang, Tie-Qiao; Wang, Tao; Chen, Liang; Shang, Hua-Yan

    2017-11-01

    In this paper, we first define each commuter's first, second and third trip costs, and then apply the full velocity difference model and the VT-Micro model to explore each commuter's three trip costs and the system's corresponding total trip costs in a traffic corridor with two entrances and one exit. The numerical results show that one entrance has prominent effects on the commuter's three trip costs and the system's corresponding total trip cost and that the impacts are directly related to the commuter's departure interval at this entrance. The results can provide some suggestions for reducing the commuters' trip costs in a traffic corridor with two entrances and one exit.

  19. Robust sparse image reconstruction of radio interferometric observations with PURIFY

    Science.gov (United States)

    Pratley, Luke; McEwen, Jason D.; d'Avezac, Mayeul; Carrillo, Rafael E.; Onose, Alexandru; Wiaux, Yves

    2018-01-01

    Next-generation radio interferometers, such as the Square Kilometre Array, will revolutionize our understanding of the Universe through their unprecedented sensitivity and resolution. However, to realize these goals significant challenges in image and data processing need to be overcome. The standard methods in radio interferometry for reconstructing images, such as CLEAN, have served the community well over the last few decades and have survived largely because they are pragmatic. However, they produce reconstructed interferometric images that are limited in quality and scalability for big data. In this work, we apply and evaluate alternative interferometric reconstruction methods that make use of state-of-the-art sparse image reconstruction algorithms motivated by compressive sensing, which have been implemented in the PURIFY software package. In particular, we implement and apply the proximal alternating direction method of multipliers algorithm presented in a recent article. First, we assess the impact of the interpolation kernel used to perform gridding and degridding on sparse image reconstruction. We find that the Kaiser-Bessel interpolation kernel performs as well as prolate spheroidal wave functions while providing a computational saving and an analytic form. Secondly, we apply PURIFY to real interferometric observations from the Very Large Array and the Australia Telescope Compact Array and find that images recovered by PURIFY are of higher quality than those recovered by CLEAN. Thirdly, we discuss how PURIFY reconstructions exhibit additional advantages over those recovered by CLEAN. The latest version of PURIFY, with developments presented in this work, is made publicly available.

  20. The evolving breast reconstruction

    DEFF Research Database (Denmark)

    Thomsen, Jørn Bo; Gunnarsson, Gudjon Leifur

    2014-01-01

    The aim of this editorial is to give an update on the use of the propeller thoracodorsal artery perforator flap (TAP/TDAP-flap) within the field of breast reconstruction. The TAP-flap can be dissected by a combined use of a monopolar cautery and a scalpel. Microsurgical instruments are generally...... not needed. The propeller TAP-flap can be designed in different ways, three of these have been published: (I) an oblique upwards design; (II) a horizontal design; (III) an oblique downward design. The latissimus dorsi-flap is a good and reliable option for breast reconstruction, but has been criticized...... for morbidity and complications. The TAP-flap does not seem to impair the function of the shoulder or arm and the morbidity appears to be scarce. However, an implant is often needed in combination with the TAP-flap, which results in implant related morbidity over time. The TAP-flap seems to be a promising tool...

  1. RISK ASSESSMENT OF ENCOUNTERING KILLER WAVES IN THE BLACK SEA

    Directory of Open Access Journals (Sweden)

    Vitaliy Ivanov

    2012-01-01

    Full Text Available The problem of assessing the risk for a vessel to encounter a killer wave in the Black Sea is considered. Analysis of in situ wave data obtained from the platform of Marine Hydrophysical Institute in the autumn of 2009 shows that occurrence frequency of abnormally high waves (freak, rogue, or killer waves varies considerably on the time scale of several hours. It is shown that the formation of such waves is associated with nonlinear processes in the wave field, presumably, with the development of modulational instability. Ninety percent of the total number of killer waves was observed in the swell wave system, and 70% of them propagated approximately in wind direction. We propose a scenario of the killer waves formation in the Black Sea. The scenario was confirmed by numerical reconstruction of the wind and wave fields in the Black Sea for the history of storms on Oct. 14, 2009 in Katsiveli and on Feb. 01, 2003 in Gelendzhik, using the MM5 mesoscale atmospheric model and the WAM-C4 wave model. A practical approach to assessing the risk for a vessel to encounter a killer wave in the Black Sea is presented.

  2. Iraq: Reconstruction Assistance

    Science.gov (United States)

    2008-05-22

    Effectiveness..., October 18, 2007, p. x. 51 Shawn Dorman, “Iraq PRTs: Pins on a Map,” Foreign Service Journal, March 2007; Testimony of Ginger Cruz, Deputy... Blood Money, Little, Brown, and Company, 2006; SIGIR, Iraq Reconstruction: Lessons in Program and Project Management, March 2007; and Glenn Zorpette...local participation that would have made projects more effective. Among widely circulated reasons were a failure to anticipate post-invasion security

  3. Reconstructing relational information.

    Science.gov (United States)

    Horecka, Kevin M; Dulas, Michael R; Schwarb, Hillary; Lucas, Heather D; Duff, Melissa; Cohen, Neal J

    2018-02-01

    Hippocampal involvement in learning and remembering relational information has an extensive history, often focusing specifically on spatial information. In humans, spatial reconstruction (SR) paradigms are a powerful tool for evaluating an individuals' spatial-relational memory. In SR tasks, participants study locations of items in space and subsequently reconstruct the studied display after a short delay. Previous work has revealed that patients with hippocampal damage are impaired both in overall placement accuracy as well as on a specific measure of relational memory efficacy, "swaps" (i.e., when the relative location of two items is reversed). However, the necessity of the hippocampus for other types of spatial-relational information involved in reconstruction behaviors (e.g., where in the environment and relative to which other items an item was located) have not yet been investigated systematically. In this work, three patients with hippocampal damage and nine healthy matched comparison participants performed an SR task. An analysis framework was developed to independently assess three first-order types of relations: (1) memory for the binding of specific item identities to locations, (2) memory for arrangement of items in relation to each other or the environment bounds, regardless of memory for the item identity, and (3) higher-order, compound relational errors (i.e., errors involving multiple pieces of relational information). Reconstruction errors were evaluated to determine the degree to which patients and comparisons differed (or not) on each type of spatial-relational information. Data revealed that the primary group difference in performance was for identity-location information. However, when the locations of items were evaluated without regarding the identities, no group difference was found in the number of item placements to studied locations. The present work provides a principled approach to analysis of SR data and clarifies our understanding of

  4. ATLAS Muon Reconstruction Efficiency

    CERN Document Server

    Spearman, W; The ATLAS collaboration

    2012-01-01

    In 2012 the LHC will be operated in a mode leading to up to 40 inelastic pp collisions per bunch crossing, so-called "pile-up". The reconstruction and identification of muons produced in a hard collisions is difficult in this challenging environment. Di-muon decays of J/ψ mesons and Z bosons have been used to study the muon reconstruction and identification efficiency of the ATLAS detector as a function of the muon transverse momentum from pT=4 GeV to pT=100 GeV and the number of inelastic collisions per event. The results show a steep efficiency turn-on curve reaching its plateau value of 100% at pT ~ 6 GeV and no dependence of the muon reconstruction efficiency on the amount pile-up. The studies also reveal that the use of inner detector tracks allows us to distinguish between isolated muons and non-isolated muons produced in jets with high separation power even at the highest pile-up levels.

  5. Reconstruction of the perineum.

    Science.gov (United States)

    Wong, David Sau-Yan

    2014-09-01

    The pelvic and perineal regions are affected by a heterogeneous spectrum of pathologies, many with a tendency to recur. Extensive mutilation carries physical, sexual, and psychological sequelae. Primary reconstruction reduces morbidity and shortens recovery. Modern management calls for a multidisciplinary approach. Not uncommonly, patients come with previous surgery and/or chemoirradiation. They may also be elderly and debilitated. The literature on reconstruction of the perineum can be confusing because knowledge has evolved by an accumulation of isolated short reports of individual methods. This led to the lack of a unifying basis for nomenclature and a failure to relate specific techniques to their roles in repairing particular types of defects. This article gives an overall summary of the approaches in a structured and rational manner. Defects of the external pelvis and perineal lining are usually amenable to coverage with local or regional fasciocutaneous flaps, if primary closure or skin graft is not appropriate. These flaps depend on the integrity of the vascular territories of the internal pudendal, the upper medial thigh plexus, or the descending branches of the inferior gluteal. The location and extent of the resection usually determine the requirements of the reconstruction and may dictate the choice of options. When defects are pelviperineal, particularly when the vagina needs to be reconstructed, myocutaneous flaps are of proven advantage in dealing with both the resurfacing as well as providing the bulk needed to fill the pelvic cavity after extensive resections. The rectus, gluteus, and gracilis are the best known options. Owing to the intrinsic limitations with the gracilis flap, the rectus and gluteus flaps have largely superseded its role in most situations. The rectus flap, in particular, provides good bulk as well as reliable skin. The use of muscle sparing flaps based on the perforator principle in suitable instances has increasingly been

  6. Measurement of sound speed vs. depth in South Pole ice: pressure waves and shear waves

    Energy Technology Data Exchange (ETDEWEB)

    IceCube Collaboration; Klein, Spencer

    2009-06-04

    We have measured the speed of both pressure waves and shear waves as a function of depth between 80 and 500 m depth in South Pole ice with better than 1% precision. The measurements were made using the South Pole Acoustic Test Setup (SPATS), an array of transmitters and sensors deployed in the ice at the South Pole in order to measure the acoustic properties relevant to acoustic detection of astrophysical neutrinos. The transmitters and sensors use piezoceramics operating at {approx}5-25 kHz. Between 200 m and 500 m depth, the measured profile is consistent with zero variation of the sound speed with depth, resulting in zero refraction, for both pressure and shear waves. We also performed a complementary study featuring an explosive signal propagating vertically from 50 to 2250 m depth, from which we determined a value for the pressure wave speed consistent with that determined for shallower depths, higher frequencies, and horizontal propagation with the SPATS sensors. The sound speed profile presented here can be used to achieve good acoustic source position and emission time reconstruction in general, and neutrino direction and energy reconstruction in particular. The reconstructed quantities could also help separate neutrino signals from background.

  7. The physics of waves

    CERN Document Server

    Georgi, Howard

    1993-01-01

    The first complete introduction to waves and wave phenomena by a renowned theorist. Covers damping, forced oscillations and resonance; normal modes; symmetries; traveling waves; signals and Fourier analysis; polarization; diffraction.

  8. Two-dimensional dissipative rogue waves due to time-delayed feedback in cavity nonlinear optics.

    Science.gov (United States)

    Tlidi, Mustapha; Panajotov, Krassimir

    2017-01-01

    We demonstrate a way to generate two-dimensional rogue waves in two types of broad area nonlinear optical systems subject to time-delayed feedback: in the generic Lugiato-Lefever model and in the model of a broad-area surface-emitting laser with saturable absorber. The delayed feedback is found to induce a spontaneous formation of rogue waves. In the absence of delayed feedback, spatial pulses are stationary. The rogue waves are exited and controlled by the delay feedback. We characterize their formation by computing the probability distribution of the pulse height. The long-tailed statistical contribution, which is often considered as a signature of the presence of rogue waves, appears for sufficiently strong feedback. The generality of our analysis suggests that the feedback induced instability leading to the spontaneous formation of two-dimensional rogue waves is a universal phenomenon.

  9. Removing Wave Artifacts from Eddy Correlation Data

    Science.gov (United States)

    Neumann, Andreas; Brand, Andreas

    2017-04-01

    The German Wadden Sea is an extensive system of back-barrier tidal basins along the margin of the southern North Sea. Due to their high productivity and the strong retention potential of labile organic carbon high mineralization rates are expected in this system. Since the sediment bed is sandy, the oxygen fluxes across the sediment-water interface (SWI) may be enhanced by strong tidal currents as well as by wind-induced surface waves. In order to measure oxygen fluxes in-situ without disturbance of the sediment, the Eddy Correlation method (ECM) was introduced to aquatic geoscience by Berg et al. (2003). The method is based on correlating turbulent fluctuations of oxygen concentration and vertical velocity measured at high frequency above the SWI. The method integrates over spatial heterogeneities and allows the observation of total benthic oxygen fluxes in complex systems where other methods like flux chamber deployments and oxygen profile measurements in the sediment fail. Therefore, the method should also reflect effects like the enhancement of oxygen fluxes by porewater advection driven by waves and currents over sandy sediments. Unfortunately the ECM suffers from wave contamination due to stirring sensitivity of the electrodes, spatial separation between the oxygen electrode and the location of velocity measurement as well as by a tilt of the measurement setup at the deployment side. In order to correct for this wave contamination we tested the method of spectral reconstruction initially introduced by Bricker and Monismith (2007) for the determination of Reynolds-stresses in wave-affected environments. In short, this method attempts to remove the wave signal from the Power spectral densities of oxygen concentration and vertical velocity fluctuations by cutting off the wave peak in these spectra. The wave contribution to the co-spectrum between both quantities is then reconstructed by assuming that the phasing in the wave band is dominated by the waves. Based

  10. Dynamics of evanescent matter waves in negative-index media

    Energy Technology Data Exchange (ETDEWEB)

    Hamamda, M; Bocvarski, V; Perales, F; Baudon, J; Dutier, G; Mainos, C; Boustimi, M; Ducloy, M, E-mail: jacques.baudon@univ-paris13.f [Laboratoire de Physique des Lasers, CNRS-UMR 7538, Universite Paris 13, 99 Av. J B Clement, 93430-Villetaneuse (France)

    2010-11-14

    Semi-evanescent and evanescent matter waves produced by an atom wave packet impinging on a repulsive barrier can be back-refracted and reconstructed by the application of negative-index 'comoving' potential pulses. One shows that those collapses and revivals generate a matter wave confined on both sides of the barrier border ('surface matter wave') and should be observable via the retardation of atom reflection from the barrier interface. This property, joined to the possibility recently demonstrated of inducing negative refraction of atom waves, makes such potentials a matter-wave counterpart of negative-index materials or 'meta materials' well known in light optics.

  11. The wave surveyor technique for fast plasma wave detection in multi-spacecraft data

    Directory of Open Access Journals (Sweden)

    J. Vogt

    2008-06-01

    Full Text Available Multi-satellite missions like Cluster allow to study the full spatio-temporal variability of plasma processes in near-Earth space, and both the frequency and the wave vector dependence of dispersion relations can be reconstructed. Existing wave analysis methods include high-resolution beamformers like the wave telescope or k-filtering technique, and the phase differencing approach that combines the correlations measured at pairs of sensors of the spacecraft array. In this paper, we make use of the eigendecomposition of the cross spectral density matrix to construct a direct wave identification method that we choose to call the wave surveyor technique. The analysis scheme extracts only the dominant wave mode but is much faster to apply than existing techniques, hence it is expected to ease survey-type detection of waves in large data sets. The wave surveyor technique is demonstrated by means of synthetic data, and is also applied to Cluster magnetometer measurements.

  12. Exit Outcomes for Probation-Supervised Youth in Foster Care: An Examination of Past Child Protection Involvement.

    Science.gov (United States)

    Eastman, Andrea Lane; Putnam-Hornstein, Emily

    2017-01-01

    Research on youth in foster care has focused on those placed for reasons of maltreatment rather than delinquency, yet most states provide foster care services to youth under probation supervision. This analysis generated knowledge about youth in probation-supervised foster care (PSFC) in California by examining the relationship between past child protective services (CPS) involvement and exit type. CPS records were extracted to identify 17-year-old youths in PSFC between 2008 and 2012 ( N = 11,188). The relationship between allegations of maltreatment and exit type was assessed using regression models. Of the PSFC youth, 64.6% had previous allegations of maltreatment and a quarter had been reported at least 6 times. Youth with a history of placement in CPS foster care were more likely to age out relative to achieving permanency in comparison to PSFC youth with no maltreatment history (relative risk ratio = 2.20; 95% confidence interval [1.90, 2.55]). As the number of reports increased, the likelihood of exiting care by aging out increased relative to achieving permanency ( p < .001). The findings suggest a majority of PSFC youth had maltreatment histories, the overlap between CPS and probation was constant, and maltreatment records may characterize youth in PSFC at risk of negative exits from care.

  13. Educational inequalities in exit from paid employment among Dutch workers: The influence of health, lifestyle and work

    NARCIS (Netherlands)

    S.J.W. Robroek (Suzan); A. Rongen (Anne); C.H. Arts (Coos); Otten, F.W.H. (Ferdy W.H.); A. Burdorf (Alex); M. Schuring (Merel)

    2015-01-01

    textabstractBackground Individuals with lower socioeconomic status are at increased risk of involuntary exit from paid employment. To give sound advice for primary prevention in the workforce, insight is needed into the role of mediating factors between socioeconomic status and labour force

  14. Development of Curriculum Content for a Unique Career Ladder Multi-Entry/Multi-Exit Nursing Program. Final Report.

    Science.gov (United States)

    Rosbach, Ellen M.

    A project was undertaken to develop the curriculum content for a unique career ladder multi-entry/multi-exit nursing program that would provide training for nurse aides, practical nurses, and registered nurses. The major objectives of the project were to conduct a review of the literature on curriculum materials presently in use, to develop 11…

  15. Assessing the Impact of Education and Marriage on Labor Market Exit Decisions of Women. Working Paper 2010-2

    Science.gov (United States)

    Hotchkiss, Julie L.; Pitts, M. Melinda; Walker, Mary Beth

    2010-01-01

    During the late 1990s, the convergence of women's labor force participation rates to men's rates came to a halt. This paper explores the degree to which the role of education and marriage in women's labor supply decisions also changed over this time period. Specifically, this paper investigates women's decisions to exit the labor market upon the…

  16. Identification of the timing-of-events model with multiple competing exit risks from single-spell data

    NARCIS (Netherlands)

    Drepper, Bettina; Effraimidis, Georgios

    2016-01-01

    The identification result of the timing-of-events model (Abbring and Van den Berg, 2003b) is extended to a model with several competing exit risk equations. This extension allows e.g. to simultaneously identify the different effects a benefit sanction has on the rate of finding work and leaving the

  17. "Stakes Is High": Culturally Relevant Practitioner Inquiry with African American Students Struggling to Pass Secondary Reading Exit Exams

    Science.gov (United States)

    Houchen, Diedre

    2013-01-01

    This article explores practitioner inquiry and culturally relevant pedagogy to create academic success with students facing high school exit examinations in Reading. In Florida, about one-third of African American students passed the test in 2010. Student perspectives on achievement, school processes, and engagement were incorporated with…

  18. Explaining the catch efficiency of different cod pots using underwater video to observe cod entry and exit behaviour

    DEFF Research Database (Denmark)

    Hedgärde, Maria; Berg, Casper Willestofte; Kindt-Larsen, Lotte

    2016-01-01

    and results showed an increase in entry rates during the night time, suggesting that lights attract fish to the pot when the dark surroundings make the effect of the light more noticeable. Exit rates in trial 1 increased with an increasing number of fish in the pot while they decreased with soak time...

  19. An Examination of the Job Training and Job Experiences of High School Students as They Exit School

    Science.gov (United States)

    Andrews, Wilbur Drew

    2010-01-01

    The purpose of this investigation was (a) to determine the level of satisfaction that exiting high school students felt regarding the job preparation and training they received in high school, (b) gather data on work experiences during high school, (c) gather data on job training experiences during high school, and (d) gather data on students…

  20. The Impact of Statewide Exit Exams: A Descriptive Case Study of Three German States with Differing Low Stakes Exam Regimes

    Science.gov (United States)

    van Ackeren, Isabell; Block, Rainer; Klein, E. Dominique; Kuhn, Svenja M.

    2012-01-01

    In this article we present results from a study investigating the impact of three state exit exam systems on teaching and learning in college-preparatory schools. The study compares one state with a traditionally more centralized exam regime, one state that is more de-centralized and one state that has recently switched to more centralized…

  1. Association between keeping home records of catheter exit-site and incidence of peritoneal dialysis-related infections.

    Science.gov (United States)

    Iida, Hidekazu; Kurita, Noriaki; Fujimoto, Shino; Kamijo, Yuka; Ishibashi, Yoshitaka; Fukuma, Shingo; Fukuhara, Shunichi

    2018-01-18

    To prevent peritoneal dialysis (PD)-related infection, components of self-catheter care have been emphasized. However, studies on the effectiveness of home recording for the prevention of PD-related infections are limited. This study aimed to examine the association between keeping home records of catheter exit site and incidence of PD-related infections. Home record books were submitted by patients undergoing PD. The proportion of days on which exit-site home recording was carried out for 120 days (0-100%) was obtained. The patients were divided into the frequent home recording group (≥ 40.5%; median value) and the infrequent home recording group (home recording groups for PD-related infection were 1.58 (95% confidence interval [CI], 0.72-3.46) in the univariate analysis and 1.49 (95% CI, 0.65-3.42) in the multivariate analysis. The IRRs of the frequent versus infrequent home recording groups for composite of surgery to create a new exit site and removal of PD catheter were 0.55 (95% CI, 0.78-3.88) and 0.35 (95% CI, 0.06-1.99), respectively. This study could not prove that keeping home records of patients' catheter exit site is associated with a lower incidence of PD-related infections.

  2. Development of a portable system of grazing exit X-Ray fluorescence applied to environmental and biological studies

    Energy Technology Data Exchange (ETDEWEB)

    Santos, Ramon S.; Oliveira, Davi F.; Anjos, Marcelino J. [Universidade do Estado do Rio de Janeiro (UERJ), RJ (Brazil). Instituto de Fisica; Assis, Joaquim T., E-mail: ramonziosp@yahoo.com.br, E-mail: davi.oliveira@uerj.br, E-mail: marcelin@uerj.br, E-mail: joaquim.iprj@gmail.com [Universidade do Estado do Rio de Janeiro (UERJ), Nova Friburgo, RJ (Brazil). Instituto Politécnico

    2017-07-01

    In this study was developed a portable system of grazing exit X-ray fluorescence (geometric 90° - 0°) that will be applied in environmental studies (aerosol samples) and biological studies. GE-XRF portable system is formed by a mini X-ray tube of low power (anode of Au, maximum voltage and current of 50 kV and 200 μA, respectively) and a SiPIN detector (model XR-100CR of the Amptek). The reflectors used as sample support (sampler carrier) were quartz discs with 25.4 mm diameter and 3.0 mm thickness. The grazing exit angle was experimentally determined by measuring a cooper solution (10 μg.g{sup -1}). The system of GE-XRF proved to be quite stable and reproducible. It was calculated the sensibility curve of the system using multielement solutions. The accuracy of the system was checked using multielement reference solution as standard reference material. The relative errors between measured and certified values are in the range of 4 to 19%. The first results showed a background was drastically reduced at grazing exit angles, enabling trace elemental analysis. This paper shows that it is possible to produce a portable system of grazing exit X-ray fluorescence compact, efficient, low-cost and easy-to-handle instrumentation using a low-power X-ray tube and a SiPIN compact detector. (author)

  3. Transnational English Language Learners Fighting on an Unlevel Playing Field: High School Exit Exams, Accommodations, and ESL Status

    Science.gov (United States)

    Alexander, Mariko Mizuno

    2017-01-01

    Though previous research addresses the negative impact of state-mandated high school exit exams on English language learners' (ELLs) educational experiences, less attention has been given to how college-oriented ELLs, especially those who attended school in their home countries before coming to the US, handle rigorous exams or gain access to…

  4. Identification of the timing-of-events model with multiple competing exit risks from single-spell data

    DEFF Research Database (Denmark)

    Drepper, Bettina; Effraimidis, G.

    2016-01-01

    The identification result of the timing-of-events model (Abbring and Van den Berg, 2003b) is extended to a model with several competing exit risk equations. This extension allows e.g. to simultaneously identify the different effects a benefit sanction has on the rate of finding work and leaving t...

  5. North Sea Storm Driving of Extreme Wave Heights

    Science.gov (United States)

    Bell, Ray; Gray, Suzanne; Jones, Oliver

    2017-04-01

    The relationship between storms and extreme ocean waves in the North sea is assessed using a long-period wave dataset and storms identified in the Interim ECMWF Re-Analysis (ERA-Interim). An ensemble sensitivity analysis is used to provide information on the spatial and temporal forcing from mean sea-level pressure and surface wind associated with extreme ocean wave height responses. Extreme ocean waves in the central North Sea arise due to either the winds in the cold conveyor belt (northerly-wind events) or winds in the warm conveyor belt (southerly-wind events) of extratropical cyclones. The largest wave heights are associated with northerly-wind events which tend to have stronger wind speeds and occur as the cold conveyor belt wraps rearwards round the cyclone to the cold side of the warm front. The northerly-wind events also provide a larger fetch to the central North Sea. Southerly-wind events are associated with the warm conveyor belts of intense extratropical storms developing in the right upper-tropospheric jet exit region. There is predictability in the extreme ocean wave events up to two days before the event associated with a strengthening of a high pressure system to the west (northerly-wind events) and south-west (southerly-wind events) of the British Isles. This acts to increase the pressure gradient over the British Isles and therefore drive stronger wind speeds in the central North sea.

  6. Reconstruction for proton computed tomography by tracing proton trajectories: a Monte Carlo study.

    Science.gov (United States)

    Li, Tianfang; Liang, Zhengrong; Singanallur, Jayalakshmi V; Satogata, Todd J; Williams, David C; Schulte, Reinhard W

    2006-03-01

    Proton computed tomography (pCT) has been explored in the past decades because of its unique imaging characteristics, low radiation dose, and its possible use for treatment planning and on-line target localization in proton therapy. However, reconstruction of pCT images is challenging because the proton path within the object to be imaged is statistically affected by multiple Coulomb scattering. In this paper, we employ GEANT4-based Monte Carlo simulations of the two-dimensional pCT reconstruction of an elliptical phantom to investigate the possible use of the algebraic reconstruction technique (ART) with three different path-estimation methods for pCT reconstruction. The first method assumes a straight-line path (SLP) connecting the proton entry and exit positions, the second method adapts the most-likely path (MLP) theoretically determined for a uniform medium, and the third method employs a cubic spline path (CSP). The ART reconstructions showed progressive improvement of spatial resolution when going from the SLP [2 line pairs (lp) cm(-1)] to the curved CSP and MLP path estimates (5 lp cm(-1)). The MLP-based ART algorithm had the fastest convergence and smallest residual error of all three estimates. This work demonstrates the advantage of tracking curved proton paths in conjunction with the ART algorithm and curved path estimates.

  7. Assessing respiratory mechanics using pressure reconstruction method in mechanically ventilated spontaneous breathing patient.

    Science.gov (United States)

    Damanhuri, Nor Salwa; Chiew, Yeong Shiong; Othman, Nor Azlan; Docherty, Paul D; Pretty, Christopher G; Shaw, Geoffrey M; Desaive, Thomas; Chase, J Geoffrey

    2016-07-01

    Respiratory system modelling can aid clinical decision making during mechanical ventilation (MV) in intensive care. However, spontaneous breathing (SB) efforts can produce entrained "M-wave" airway pressure waveforms that inhibit identification of accurate values for respiratory system elastance and airway resistance. A pressure wave reconstruction method is proposed to accurately identify respiratory mechanics, assess the level of SB effort, and quantify the incidence of SB effort without uncommon measuring devices or interruption to care. Data from 275 breaths aggregated from all mechanically ventilated patients at Christchurch Hospital were used in this study. The breath specific respiratory elastance is calculated using a time-varying elastance model. A pressure reconstruction method is proposed to reconstruct pressure waves identified as being affected by SB effort. The area under the curve of the time-varying respiratory elastance (AUC Edrs) are calculated and compared, where unreconstructed waves yield lower AUC Edrs. The difference between the reconstructed and unreconstructed pressure is denoted as a surrogate measure of SB effort. The pressure reconstruction method yielded a median AUC Edrs of 19.21 [IQR: 16.30-22.47]cmH2Os/l. In contrast, the median AUC Edrs for unreconstructed M-wave data was 20.41 [IQR: 16.68-22.81]cmH2Os/l. The pressure reconstruction method had the least variability in AUC Edrs assessed by the robust coefficient of variation (RCV)=0.04 versus 0.05 for unreconstructed data. Each patient exhibited different levels of SB effort, independent from MV setting, indicating the need for non-invasive, real time assessment of SB effort. A simple reconstruction method enables more consistent real-time estimation of the true, underlying respiratory system mechanics of a SB patient and provides the surrogate of SB effort, which may be clinically useful for clinicians in determining optimal ventilator settings to improve patient care. Copyright

  8. Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

    Directory of Open Access Journals (Sweden)

    Angelique Riepsamen

    Full Text Available Following exit from meiosis I, mammalian oocytes immediately enter meiosis II without an intervening interphase, accompanied by rapid reassembly of a bipolar spindle that maintains condensed chromosomes in a metaphase configuration (metaphase II arrest. Here we study the effect of nicotinamide (NAM, a non-competitive pan-sirtuin inhibitor, during meiotic maturation in mouse oocytes. Sirtuins are a family of seven NAD+-dependent deacetylases (Sirt1-7, which are involved in multiple cellular processes and are emerging as important regulators in oocytes and embryos. We found that NAM significantly delayed entry into meiosis I associated with delayed accumulation of the Cdk1 co-activator, cyclin B1. GVBD was also inhibited by the Sirt2-specific inhibitor, AGK2, and in a very similar pattern to NAM, supporting the notion that as in somatic cells, NAM inhibits sirtuins in oocytes. NAM did not affect subsequent spindle assembly, chromosome alignment or the timing of first polar body extrusion (PBE. Unexpectedly, however, in the majority of oocytes with a polar body, chromatin was decondensed and a nuclear structure was present. An identical phenotype was observed when flavopiridol was used to induce Cdk1 inactivation during late meiosis I prior to PBE, but not if Cdk1 was inactivated after PBE when metaphase II arrest was already established, altogether indicating that NAM impaired establishment rather than maintenance of metaphase II arrest. During meiosis I exit in NAM-treated medium, we found that cyclin B1 levels were lower and inhibitory Cdk1 phosphorylation was increased compared with controls. Although activation of the anaphase-promoting complex-Cdc20 (APC-Cdc20 occurred on-time in NAM-treated oocytes, Cdc20 levels were higher in very late meiosis I, pointing to exaggerated APC-Cdc20-mediated proteolysis as a reason for lower cyclin B1 levels. Collectively, therefore, our data indicate that by disrupting Cdk1 regulation, NAM impairs entry into

  9. Peritoneal catheters and exit-site practices toward optimum peritoneal access: a review of current developments.

    Science.gov (United States)

    Flanigan, Michael; Gokal, Ram

    2005-01-01

    This review updates the 1998 International Society for Peritoneal Dialysis (ISPD) recommendations for peritoneal dialysis catheters and exit-site practices (Gokal R, et al. Peritoneal catheters and exit-site practices toward optimum peritonealaccess: 1998 update. Perit Dial Int 1998; 18:11-33.) The Ovid and PubMed search engines were used to review the Medline databases of January 1980 through June 2003. Searches were restricted to human data; primary key word searches included dialysis, peritoneal dialysis, and continuous ambulatory peritoneal dialysis cross referenced with access, catheter, dialysis catheter, peritoneal dialysis catheter, and Tenckhoff catheter. Related searches were provided via the PubMed related articles link. Reports were selected if they provided identifiable information on catheter design, catheter placement technique, and survival or placement complications. Reports without such data were excluded from review. Each study was then categorized by its characteristics: single-center or multicenter; retrospective or prospective; controlled trial, with or without random patient assignment; or review article. There are few randomized controlled evaluations testing how catheter design and/or placement influence long-term survival and function, and these are typically conducted at a single center. The majority of reports represent retrospective single-center experiences, and these are supplemented by occasional multicenter data registries. There is substantial variability in catheter outcomes between centers, and this variability is more closely correlated with operator and center characteristics than with catheter design. Some catheter designs appear to impact long-term catheter success, and, in some cases, specific patient characteristics and dialysis formats combine with specific catheter designs to influence catheter survival. Most reporters prefer two-cuff designs and placement of the deep cuff at an intramuscular location. Intramuscular cuff

  10. Nicotinamide impairs entry into and exit from meiosis I in mouse oocytes.

    Science.gov (United States)

    Riepsamen, Angelique; Wu, Lindsay; Lau, Laurin; Listijono, Dave; Ledger, William; Sinclair, David; Homer, Hayden

    2015-01-01

    Following exit from meiosis I, mammalian oocytes immediately enter meiosis II without an intervening interphase, accompanied by rapid reassembly of a bipolar spindle that maintains condensed chromosomes in a metaphase configuration (metaphase II arrest). Here we study the effect of nicotinamide (NAM), a non-competitive pan-sirtuin inhibitor, during meiotic maturation in mouse oocytes. Sirtuins are a family of seven NAD+-dependent deacetylases (Sirt1-7), which are involved in multiple cellular processes and are emerging as important regulators in oocytes and embryos. We found that NAM significantly delayed entry into meiosis I associated with delayed accumulation of the Cdk1 co-activator, cyclin B1. GVBD was also inhibited by the Sirt2-specific inhibitor, AGK2, and in a very similar pattern to NAM, supporting the notion that as in somatic cells, NAM inhibits sirtuins in oocytes. NAM did not affect subsequent spindle assembly, chromosome alignment or the timing of first polar body extrusion (PBE). Unexpectedly, however, in the majority of oocytes with a polar body, chromatin was decondensed and a nuclear structure was present. An identical phenotype was observed when flavopiridol was used to induce Cdk1 inactivation during late meiosis I prior to PBE, but not if Cdk1 was inactivated after PBE when metaphase II arrest was already established, altogether indicating that NAM impaired establishment rather than maintenance of metaphase II arrest. During meiosis I exit in NAM-treated medium, we found that cyclin B1 levels were lower and inhibitory Cdk1 phosphorylation was increased compared with controls. Although activation of the anaphase-promoting complex-Cdc20 (APC-Cdc20) occurred on-time in NAM-treated oocytes, Cdc20 levels were higher in very late meiosis I, pointing to exaggerated APC-Cdc20-mediated proteolysis as a reason for lower cyclin B1 levels. Collectively, therefore, our data indicate that by disrupting Cdk1 regulation, NAM impairs entry into meiosis I and

  11. On Stack Reconstruction Problem

    Directory of Open Access Journals (Sweden)

    V. D. Аkeliev

    2009-01-01

    Full Text Available The paper describes analytical investigations that study relation of fuel combustion regimes with concentration values of sulphur anhydride in flue gases and acid dew point. Coefficients of convective heat transfer at internal and external surfaces of stacks have been determined in the paper. The paper reveals the possibility to reconstruct stacks while using gas discharging channel made of composite material on the basis of glass-reinforced plastic which permits to reduce thermo-stressed actions on reinforced concrete and increase volume of released gases due to practically two-fold reduction of gas-dynamic pressure losses along the pipe length.

  12. Theoretical and Experimental Studies of Wave Impact underneath Decks of Offshore Platforms

    Energy Technology Data Exchange (ETDEWEB)

    Baarholm, Rolf Jarle

    2001-07-01

    structure experiences a positive slamming dominated force (upward directed) during the initial water entry phase, followed by a negative force during the water exit phase. The force in the latter phase is dominated by a negative added mass force due to negative vertical fluid particle accelerations in the wave crest. The positive force peak is highly dependent on the impact condition and is especially sensitive to the initial deck clearance. The magnitude of the negative force peak is less dependent on the impact condition. This peak occurs when the wetting of the deck is at its maximum and its magnitude may be larger than the positive force peak. Thus, the water exit phase is important for global effects. The initial impact yields the highest average pressures and is critical for local structural response in the deck. Comparisons between experiments and theory have been performed for a number of impact conditions. Second order Stokes' theory is used to describe the incident waves. The Wagner based method describes the water entry phase well. Both the magnitude and the duration of the positive force peak are well predicted. The computations for the water exit phase are less satisfactory. The WBM overestimates the magnitude of the negative force peak and it underestimates the duration of the water exit phase. In the nonlinear boundary element method, the impact induced vertical force on the deck is calculated by imposing conservation of fluid momentum and by using direct pressure integration. These two approaches yield similar force histories except during the final stage of water exit, where they tend to diverge. This is caused by inaccuracies in the numerical solution and in the formulation of the boundary value problem. The force at this stage is small. The BEM yields results that compare well with experiments for both the water entry and the water exit phase. Especially for the water exit phase the BEM is superior to the Wagner based method. (author)

  13. Non-microsurgical breast reconstruction

    Directory of Open Access Journals (Sweden)

    Sharma Sheel

    2007-12-01

    Full Text Available Breast reconstruction after mastectomy should aim at resulting in an aesthetic outcome that matches the patient′s expectations and without interfering in the oncologic treatment. Whether the reconstruction is performed immediately or in a delayed fashion depends on various factors, which needs detailed attention. Autologous tissue, implants or both are used in the reconstruction. This article reviews the current concepts in these, with emphasis on non-microsurgical methods of using the autologous tissue for reconstruction. Breast conservation has become an accepted practice of treatment. Reconstruction in these situations as well as in an occasion when the surgery is done for failed breast conservation is discussed in detail. The article also reviews the various methods for nipple reconstruction available.

  14. Simultaneous reconstruction of temperature field and radiative properties by inverse radiation analysis using stochastic particle swarm optimization

    Directory of Open Access Journals (Sweden)

    Liu Dong

    2016-01-01

    Full Text Available Simultaneous reconstruction of temperature field and radiative properties including scattering albedo and extinction coefficient is presented in a two-dimensional (2-D rectangular, absorbing, emitting and isotropically scattering gray medium from the knowledge of the exit radiative intensities received by charge-coupled device (CCD cameras at boundary surfaces. The inverse problem is formulated as a non-linear optimization problem and solved by stochastic particle swarm optimization. The effects of particle swarm size, generation number, measurement errors, and optical thickness on the accuracy of the estimation, and computing time were investigated and the results show that the temperature field and radiative properties can be reconstructed well for the exact and noisy data, but radiative properties are harder to obtain than temperature field. Moreover, the extinction coefficient is more difficult to reconstruct than scattering albedo.

  15. Long-Term Effects of the Implementation of State-Wide Exit Exams: A Multilevel Regression Analysis of Mediation Effects of Teaching Practices on Students' Motivational Orientations

    Science.gov (United States)

    Maag Merki, Katharina; Oerke, Britta

    2017-01-01

    This study extends previous research investigating the effects of state-wide exit exams by studying the change from a class-based to a state-wide exit exam system over 5 years, using multilevel analyses and examining mediating effects of teachers' practices on students' motivational orientations. In this multi-cohort study, we analyzed in…

  16. LHCb; LHCb Jet Reconstruction

    CERN Multimedia

    Augusto, O

    2012-01-01

    The Large Hadron Collider (LHC) is the most powerful particle accelerator in the world. It has been designed to collide proton beams at an energy up to 14 TeV in the center of mass. In 2011, the data taking was done with a center of mass energy of 7 TeV, the instant luminosity has reached values greater than $4 \\times 10^{32} cm^{-2} s^{-1}$ and the integrated luminosity reached the value of 1.02 $fb^{-1}$ on the LHCb. The jet reconstruction is fundamental to observe events that can be used to test pertubative QCD (pQCD). It also provides a way to observe standard model channels and searches for new physics like SUSY. The anti-kt algorithm is a jet reconstruction algorithm that is based on the distance of the particles on the space $\\eta \\times \\phi$ and on the transverse momentum of particles. To maximize the energy resolution all information about the trackers and the calo...

  17. Reconstruction of Fine Scale Auroral Dynamics

    CERN Document Server

    Hirsch, Michael; Zettergren, Matthew; Dahlgren, Hanna; Goenka, Chhavi; Akbari, Hassanali

    2015-01-01

    We present a feasibility study for a high frame rate, short baseline auroral tomographic imaging system useful for estimating parametric variations in the precipitating electron number flux spectrum of dynamic auroral events. Of particular interest are auroral substorms, characterized by spatial variations of order 100 m and temporal variations of order 10 ms. These scales are thought to be produced by dispersive Alfv\\'en waves in the near-Earth magnetosphere. The auroral tomography system characterized in this paper reconstructs the auroral volume emission rate to estimate the characteristic energy and location in the direction perpendicular to the geomagnetic field of peak electron precipitation flux using a distributed network of precisely synchronized ground-based cameras. As the observing baseline decreases, the tomographic inverse problem becomes highly ill-conditioned; as the sampling rate increases, the signal-to-noise ratio degrades and synchronization requirements become increasingly critical. Our a...

  18. Bionic approach for the prevention of exit-site infections of percutaneous devices.

    Science.gov (United States)

    Großhauser, Johannes; Reiter, Katja; Große-Siestrup, Christian; Kikhney, Judith; Kertzscher, Ulrich; Affeld, Klaus

    2015-06-01

    Exit-site infections remain one of the main complications for percutaneous devices, such as catheters for peritoneal dialysis or drivelines for ventricular assist devices. Many efforts have been made to create a biological seal, yet without long-term success. This study investigates a new kind of percutaneous device which is coated with an extricable polymeric membrane. The bionic approach applies the naturally outwards directed growth of skin structures to technology: by pulling the protective membrane it slowly grows out of the body and a developing sulcus is exposed to dry air and an infection is avoided. In a feasibility study this kind of device was shown to reduce the rate of infection. To further investigate these devices, they were implanted in the skin of goats and observed for a period of more than 500 days. The membranes were pulled with a force of up to 2 N and the resulting movement was recorded. When being pulled, the membranes moved 0.4-0.9 mm per week, showing that the application of a continuously acting, defined force on the protective membrane causes the desired slow movement.

  19. Regional Innovation System Strengthening Program (SIDa as an Exit Strategy National Community Development Program (PNPM

    Directory of Open Access Journals (Sweden)

    Teguh Narutomo

    2014-06-01

    Full Text Available The aim of this study was to evaluate the PNPM program and follow the program with SIDA Strengthening Program. The research method used is a qualitative method approach of this research through the evaluation research design that builds on the CIPP evaluation model (Context-Input-Process-Product. Since the failure of theories and models of development are too glorifies growth, makes many people turn to focus on people development, which includes requiring optimization of local resources, participation, and empowerment. Since then, "empowerment" which was introduced in Indonesia has been anesthetized and made many hopes among many parties. In 2007 started the National Program for Community Empowerment (PNPM which continue Kecamatan Development Program (KDP. PNPM 2014 which is part of the United Indonesia Cabinet Volume 2 is going to end. For that we need to look for an exit strategy program that can maintain sustainability of PNPM. Regional Innovation Systems Strengthening Program (SIDA is a program of the whole process in one system to foster innovation made between government institutions, local governments, research institutions, educational institutions, innovation support institutions, businesses, and communities in areas that have been implemented since the 2012 SIDA program is an empowerment program as well, both to the public and even empowering to all elements such as academia, private industry, government and society.

  20. The back and forth of cargo exit from the endoplasmic reticulum.

    Science.gov (United States)

    Geva, Yosef; Schuldiner, Maya

    2014-02-03

    Endoplasmic reticulum (ER) to Golgi trafficking is an essential step in sorting mature, correctly folded, processed and assembled proteins (cargo) from immature proteins and ER-resident proteins. However, the mechanisms governing trafficking selectivity, specificity and regulation are not yet fully understood. To date, three complementary mechanisms have been described that enable regulation of this trafficking step: ER retention of immature proteins in the ER; selective uptake of fully mature proteins into Golgi-bound vesicles; and retrieval from the Golgi of immature cargo that has erroneously exited the ER. Together, these three mechanisms allow incredible specificity and enable the cell to carry out protein quality control and regulate protein processing, oligomerization and expression. This review will focus on the current knowledge of selectivity mechanisms acting during the ER-to-Golgi sorting step and their significance in health and disease. The review will also highlight several key questions that have remained unanswered and discuss the future frontiers. Copyright © 2014 Elsevier Ltd. All rights reserved.